page_title: FAM149A
section_title: Expression
hierarchical_section_title: FAM149A / Expression / Expression
caption_attribution_description: English: Example of Actin Beta protein expression in mouse brain.
context_page_description: Family with sequence similarity 149, member A is a protein that in humans is encoded by the FAM149A gene. It is well conserved in primates, dog, cow, mouse, rat, and chicken. It has one paralog, FAM149B.
context_section_description: Based on the graphs on the right, the highest levels of expression occur in the trigeminal ganglion, superior cervical ganglion, atrioventricular node (heart), and kidney.  However, at least a small amount seems to be expressed in almost all tissues in the human body. Using the same micro arrays provided by Bio GPS, expression of FAM149A was found to vary through the shedding of the endometrium during menstruation. This opens a new avenue for possible exploration of the function of the gene.
  A search was performed on the Allen Brain Atlas using FAM149A. According to the levels of expression provided by the Atlas, FAM149A is not expressed in notable levels within the mouse brain.  However, with visual observation of the figure, FAM149A could be found in the ventral posterior complex of the thalamus.  This can be seen as the dark vertical line in the center of the sagittal brain slice in the image below.  As a comparison, the expression of the protein, actin, is used to demonstrate what a mouse brain appears like with high levels of expression.
caption: Example of Actin Beta protein expression in mouse brain.
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