page_title: Pho4
hierarchical_section_title: Pho4
caption_attribution_description: English: Crystallographic structure of the yeast Pho4/DNA complex based on PDB: 1a0a&#8203; coordinates.
context_page_description: Pho4 is a basic helix-loop-helix transcription factor found in S. cerevisiae and other yeasts.
  The Pho4 homodimer binds to DNA sequences containing the bHLH binding site 5'-CACGTG-3'. This sequence is found in the promoters of genes upregulated in response to phosphate availability such as the PHO5 gene.
context_section_description: Pho4 is a basic helix-loop-helix (bHLH) transcription factor found in S. cerevisiae and other yeasts.
  The Pho4 homodimer binds to DNA sequences containing the bHLH binding site 5'-CACGTG-3'.  This sequence is found in the promoters of genes upregulated in response to phosphate availability such as the PHO5 gene.
caption: Crystallographic structure of yeast Pho4 homodimer (cyan and green) complexed with DNA (brown).[1]
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