page_title: DAHP synthase
hierarchical_section_title: DAHP synthase
caption_attribution_description: English: Cartoon representation of the molecular structure of protein registered with 1pck code. Deutsch: Grafik des Molekularstruktur von jenem Protein, das mit 1pck code registriert ist. Plattdüütsch: Grafik, de de Molekularstruktur von dat Protein wiest, dat mit’n Kood 1pck registreert is.
context_page_description: 3-Deoxy-D-arabinoheptulosonate 7-phosphate synthase is the first enzyme in a series of metabolic reactions known as the shikimate pathway, which is responsible for the biosynthesis of the amino acids phenylalanine, tyrosine, and tryptophan. Since it is the first enzyme in the shikimate pathway, it controls the amount of carbon entering the pathway. Enzyme inhibition is the primary method of regulating the amount of carbon entering the pathway. Forms of this enzyme differ between organisms, but can be considered DAHP synthase based upon the reaction that is catalyzed by this enzyme.
  In enzymology, a DAHP synthase is an enzyme that catalyzes the chemical reaction
  phosphoenolpyruvate + D-erythrose 4-phosphate + H₂O 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate
  The three substrates of this enzyme are phosphoenolpyruvate, D-erythrose 4-phosphate, and H₂O, whereas its two products are 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate and phosphate.
context_section_description: 3-Deoxy-D-arabinoheptulosonate 7-phosphate (DAHP) synthase (EC 2.5.1.54) is the first enzyme in a series of metabolic reactions known as the shikimate pathway, which is responsible for the biosynthesis of the amino acids phenylalanine, tyrosine, and tryptophan. Since it is the first enzyme in the shikimate pathway, it controls the amount of carbon entering the pathway. Enzyme inhibition is the primary method of regulating the amount of carbon entering the pathway. Forms of this enzyme differ between organisms, but can be considered DAHP synthase based upon the reaction that is catalyzed by this enzyme.
  In enzymology, a DAHP synthase (EC 2.5.1.54) is an enzyme that catalyzes the chemical reaction
  phosphoenolpyruvate + D-erythrose 4-phosphate + H₂O  3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate
  The three substrates of this enzyme are phosphoenolpyruvate, D-erythrose 4-phosphate, and H₂O, whereas its two products are 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate and phosphate.
caption: Structure of Aquifex aeolicus kdo8ps in complex with z-methyl-pep 2-dehydro-3-deoxyphosphooctonate aldolase.[1]
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