page_title: Vesicle-associated membrane protein
hierarchical_section_title: Vesicle-associated membrane protein
caption_attribution_description: Deutsch: 3 verschiedene Ansichten der Struktur eines abgekürzten neuronalen SNARE Komplexes. Legende: Synaptobrevin-2 (rot), Syntaxin-1 (rosa), SNAP-25 (violett). Weitere Darstellungen aus der Proteindatenbank: http://www.rcsb.org/pdb/explore.do?structureId=1N7S
context_page_description: Vesicle associated membrane proteins are a family of SNARE proteins with similar structure, and are mostly involved in vesicle fusion.
  VAMP1 and VAMP2 proteins known as synaptobrevins are expressed in brain and are constituents of the synaptic vesicles, where they participate in neurotransmitter release.
  VAMP3 is ubiquitously expressed and participates in regulated and constitutive exocytosis as a constituent of secretory granules and secretory vesicles.
  VAMP5 and VAMP7 participate in constitutive exocytosis.
  VAMP5 is a constituent of secretory vesicles, myotubes and tubulovesicular structures.
  VAMP7 is found both in secretory granules and endosomes.
  VAMP8 participates in endocytosis and is found in early endosomes. VAMP8 also participates the regulated exocytosis in pancreatic acinar cells.
  VAMP4 is involved in transport from the Golgi.
context_section_description: Vesicle associated membrane proteins (VAMP) are a family of SNARE proteins with similar structure, and are mostly involved in vesicle fusion.
  VAMP1 and VAMP2 proteins known as synaptobrevins are expressed in brain and are constituents of the synaptic vesicles, where they participate in neurotransmitter release.
  VAMP3 (known as cellubrevin) is ubiquitously expressed and participates in regulated and constitutive exocytosis as a constituent of secretory granules and secretory vesicles.
  VAMP5 and VAMP7 (SYBL1) participate in constitutive exocytosis.
  VAMP5 is a constituent of secretory vesicles, myotubes and tubulovesicular structures.
  VAMP7 is found both in secretory granules and endosomes.
  VAMP8 (known as endobrevin) participates in endocytosis and is found in early endosomes. VAMP8 also participates the regulated exocytosis in pancreatic acinar cells.
  VAMP4 is involved in transport from the Golgi.
caption: Three different views of the high resolution structure of a truncated neuronal SNARE complex. Legend: synaptobrevin-2 (red), Syntaxin-1 (pink), SNAP-25 (purple).
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