page_title: Cbl TKB domain
hierarchical_section_title: Cbl TKB domain
caption_attribution_description: English: Cartoon representation of the molecular structure of protein registered with 1b47 code. Deutsch: Grafik des Molekularstruktur von jenem Protein, das mit 1b47 code registriert ist. Plattdüütsch: Grafik, de de Molekularstruktur von dat Protein wiest, dat mit’n Kood 1b47 registreert is.
context_page_description: In molecular biology, the Cbl TKB domain, also known as the phosphotyrosine binding domain is a conserved region found at the N-terminus of Cbl adaptor proteins. This N-terminal region is composed of three evolutionarily conserved domains: an N-terminal four-helix bundle domain, an EF hand-like domain and a SH2-like domain, which together are known to bind to phosphorylated tyrosine residues.
context_section_description: In molecular biology, the Cbl TKB domain (tyrosine kinase binding domain), also known as the phosphotyrosine binding (PTB) domain is a conserved region found at the N-terminus of Cbl adaptor proteins.  This N-terminal region is composed of three evolutionarily conserved domains: an N-terminal four-helix bundle domain, an EF hand-like domain and a SH2-like domain, which together are known to bind to phosphorylated tyrosine residues.
caption: structure of the n-terminal domain of cbl in complex with its binding site in zap-70
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