page_title: Histone H1
section_title: Structure
hierarchical_section_title: Histone H1 / Structure
caption_attribution_description: A 3-D Illustration of the basic structure of a nucleosome Created in Blender3D and annotated with TheGIMP
context_page_description: Histone H1 is one of the five main histone protein families which are components of chromatin in eukaryotic cells. Though highly conserved, it is nevertheless the most variable histone in sequence across species.
context_section_description: Metazoan H1 proteins feature a central globular "winged helix" domain and long C- and short N-terminal tails. H1 is involved with the packing of the "beads on a string" sub-structures into a high order structure, whose details have not yet been solved. H1 found in protists and bacteria, otherwise known as nucleoprotein HC1/HC2 (Pfam PF07382), lack the central domain and the N-terminal tail.
  H1 is less conserved than core histones. The globular domain is the most conserved part of H1.
caption: A diagram showing where H1 can be found in the nucleosome
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