Document:

Form of Debt Securities Warrant Agreement and Warrant Certificate

 EXHIBIT 4.10 
  
 TERCICA, INC. 
  
 and 
  
             , AS WARRANT AGENT 
  
 FORM OF DEBT SECURITIES 
 WARRANT
AGREEMENT 
  
 DATED AS OF
                     

 TERCICA, INC. 
  
 FORM OF DEBT SECURITIES WARRANT AGREEMENT 
  
 DEBT SECURITIES WARRANT AGREEMENT (this
“Agreement”), dated as of                      between TERCICA, INC., a Delaware
corporation (the “Company”) and                     , a [corporation] [national banking association] organized and existing
under the laws of                      and having a corporate trust office in
                    , as warrant agent (the “Warrant Agent”). 
  
 WHEREAS, the Company has entered into an indenture dated as of
[                     (the “Senior Indenture”), with
                    , as trustee (such trustee, and any successors to such trustee, herein called the “Senior Trustee”),
providing for the issuance from time to time of its unsubordinated debt securities, to be issued in one or more series as provided in the Senior Indenture (the “Debt Securities”);]
[                     (the “Subordinated Indenture”), with
                    , as trustee (such trustee, and any successors to such trustee, herein called the “Subordinated
Trustee”), providing for the issuance from time to time of its subordinated debt securities, to be issued in one or more series as provided in the Subordinated Indenture (the “Debt Securities”);] 
  
 WHEREAS, the Company proposes to sell [If Warrants are
sold with other securities—title of such other Securities being offered (the “Other Securities”) with] warrant certificates evidencing one or more warrants (the “Warrants” or, individually, a “Warrant”)
representing the right to purchase [title of Debt Securities purchasable through exercise of Warrants] (the “Warrant Debt Securities”), such warrant certificates and other warrant certificates issued pursuant to this Agreement being herein
called the “Warrant Certificates”; and 
  
 WHEREAS, the Company desires the Warrant Agent to act on behalf of the Company, and the Warrant Agent is willing so to act, in connection with the issuance, registration, transfer, exchange, exercise and replacement of
the Warrant Certificates, and in this Agreement wishes to set forth, among other things, the form and provisions of the Warrant Certificates and the terms and conditions on which they may be issued, registered, transferred, exchanged, exercised and
replaced. 
  
 NOW, THEREFORE,
in consideration of the premises and of the mutual agreements herein contained, the parties hereto agree as follows: 
  
 ARTICLE 1 
  
 ISSUANCE OF WARRANTS AND EXECUTION AND DELIVERY OF WARRANT 
 CERTIFICATES

  
 1.1 Issuance of Warrants. [If Warrants
alone—Upon issuance, each Warrant Certificate shall evidence one or more Warrants.] [If Other Securities and Warrants—Warrant Certificates shall be [initially] issued in connection with the issuance of the Other Securities [but shall be
separately transferable on and after                      (the “Detachable Date”)] [and shall not 

 be separately transferable] and each Warrant Certificate shall evidence one or more Warrants.] Each Warrant evidenced
thereby shall represent the right, subject to the provisions contained herein and therein, to purchase one Warrant Debt Security. [If Other Securities and Warrants—Warrant Certificates shall be initially issued in units with the Other
Securities and each Warrant Certificate included in such a unit shall evidence                      Warrants for each
[$                     principal amount] [             shares] of Other
Securities included in such unit.]. 
  
 1.2 Execution
and Delivery of Warrant Certificates. Each Warrant Certificate, whenever issued, shall be in registered form substantially in the form set forth in Exhibit A hereto, shall be dated the date of its countersignature by the Warrant Agent and may
have such letters, numbers, or other marks of identification or designation and such legends or endorsements printed, lithographed or engraved thereon as the officers of the Company executing the same may approve (execution thereof to be conclusive
evidence of such approval) and as are not inconsistent with the provisions of this Agreement, or as may be required to comply with any law or with any rule or regulation made pursuant thereto or with any rule or regulation of any securities exchange
on which the Warrants may be listed, or to conform to usage. The Warrant Certificates shall be signed on behalf of the Company by any of its present or future chief executive officers, presidents, senior vice presidents, vice presidents, chief
financial officers, chief legal officers, treasurers, assistant treasurers, controllers, assistant controllers, secretaries or assistant secretaries under its corporate seal reproduced thereon. Such signatures may be manual or facsimile signatures
of such authorized officers and may be imprinted or otherwise reproduced on the Warrant Certificates. The seal of the Company may be in the form of a facsimile thereof and may be impressed, affixed, imprinted or otherwise reproduced on the Warrant
Certificates. 
  
 No Warrant Certificate shall be valid for any
purpose, and no Warrant evidenced thereby shall be exercisable, until such Warrant Certificate has been countersigned by the manual signature of the Warrant Agent. Such signature by the Warrant Agent upon any Warrant Certificate executed by the
Company shall be conclusive evidence that the Warrant Certificate so countersigned has been duly issued hereunder. 
  
 In case any officer of the Company who shall have signed any of the Warrant Certificates either manually or by facsimile signature shall cease to be such
officer before the Warrant Certificates so signed shall have been countersigned and delivered by the Warrant Agent, such Warrant Certificates may be countersigned and delivered notwithstanding that the person who signed Warrant Certificates ceased
to be such officer of the Company; and any Warrant Certificate may be signed on behalf of the Company by such persons as, at the actual date of the execution of such Warrant Certificate, shall be the proper officers of the Company, although at the
date of the execution of this Agreement any such person was not such officer. 
  
 The term “holder” or “holder of a Warrant Certificate” as used herein shall mean any person in whose name at the time any Warrant Certificate shall be registered upon the books to be maintained by
the Warrant Agent for that purpose [If Other Securities and Warrants are not immediately detachable—or upon the registration of the Other Securities prior to the Detachable Date. Prior to the Detachable Date, the Company will, or will cause the
registrar of the Other Securities to, make available at all times to the Warrant Agent such information as to holders of the Other Securities as may be necessary to keep the Warrant Agent’s records up to date]. 
  

 2. 

 1.3 Issuance of Warrant Certificates. Warrant Certificates evidencing the right to purchase
Warrant Debt Securities may be executed by the Company and delivered to the Warrant Agent upon the execution of this Warrant Agreement or from time to time thereafter. The Warrant Agent shall, upon receipt of Warrant Certificates duly executed on
behalf of the Company, countersign such Warrant Certificates and shall deliver such Warrant Certificates to or upon the order of the Company. 
  
 ARTICLE 2 
  
 WARRANT PRICE, DURATION AND EXERCISE OF WARRANTS 
  
 2.1 Warrant Price. During the period specified in Section 2.2, each Warrant shall, subject to the terms of this Warrant Agreement and the
applicable Warrant Certificate, entitle the holder thereof, to purchase the principal amount of Warrant Debt Securities specified in the applicable Warrant Certificate at an exercise price of
            % of the principal amount thereof [plus accrued amortization, if any, of the original issue discount of the Warrant Debt Securities] [plus accrued interest, if
any, from the most recent date from which interest shall have been paid on the Warrant Debt Securities or, if no interest shall have been paid on the Warrant Debt Securities, from the date of their initial issuance.] [The original issue discount
($             for each $1,000 principal amount of Warrant Debt Securities) will be amortized at a
            % annual rate, computed on a[n] [semi-] annual basis [using a 360-day year consisting of twelve 30-day months].] Such purchase price for the Warrant Debt
Securities is referred to in this Agreement as the “Warrant Price.” 
  
 2.2 Duration of Warrants. Each Warrant may be exercised in whole or in part at any time, as specified herein, on or after [the date thereof]
[            ] and at or before [            ] p.m., [City] time, on
                     or such later date as the Company may designate by notice to the Warrant Agent and the holders of Warrant
Certificates mailed to their addresses as set forth in the record books of the Warrant Agent (the “Expiration Date”). Each Warrant not exercised at or before [            ]
p.m., [City] time, on the Expiration Date shall become void, and all rights of the holder of the Warrant Certificate evidencing such Warrant under this Agreement shall cease. 
  
 2.3 Exercise Of Warrants. 
  

(a) During the period specified in Section 2.2, the Warrants may be exercised to purchase a whole number of Warrant Debt Securities in
registered form by providing certain information as set forth on the reverse side of the Warrant Certificate and by paying in full, in lawful money of the United States of America, [in cash or by certified check or official bank check in New York
Clearing House funds] [by bank wire transfer in immediately available funds] the Warrant Price for each Warrant Debt Security with respect to which a Warrant is being exercised to the Warrant Agent at its corporate trust office, provided that such
exercise is subject to receipt within five business days of such payment by the Warrant Agent of the Warrant Certificate with the form of election to purchase Warrant Debt Securities set forth on the reverse side of the Warrant Certificate properly
completed and duly executed. The date on which payment in full of the Warrant Price is received by the Warrant Agent shall, subject to receipt of the Warrant Certificate as aforesaid, be deemed to be the date on which the Warrant is exercised;

  

 3. 

 provided, however, that if, at the date of receipt of such Warrant Certificates and payment in full of the Warrant Price,
the transfer books for the Warrant Debt Securities purchasable upon the exercise of such Warrants shall be closed, no such receipt of such Warrant Certificates and no such payment of such Warrant Price shall be effective to constitute the person so
designated to be named as the holder of record of such Warrant Debt Securities on such date, but shall be effective to constitute such person as the holder of record of such Warrant Debt Securities for all purposes at the opening of business on the
next succeeding day on which the transfer books for the Warrant Debt Securities purchasable upon the exercise of such Warrants shall be opened, and the certificates for the Warrant Debt Securities in respect of which such Warrants are then exercised
shall be issuable as of the date on such next succeeding day on which the transfer books shall next be opened, and until such date the Company shall be under no duty to deliver any certificate for such Warrant Debt Securities. The Warrant Agent
shall deposit all funds received by it in payment of the Warrant Price in an account of the Company maintained with it and shall advise the Company by telephone at the end of each day on which a payment for the exercise of Warrants is received of
the amount so deposited to its account. The Warrant Agent shall promptly confirm such telephone advice to the Company in writing. 
  
 (b) The Warrant Agent shall, from time to time, as promptly as practicable, advise the Company of (i) the number of Warrant Debt Securities with
respect to which Warrants were exercised, (ii) the instructions of each holder of the Warrant Certificates evidencing such Warrants with respect to delivery of the Warrant Debt Securities to which such holder is entitled upon such exercise, (iii)
delivery of Warrant Certificates evidencing the balance, if any, of the Warrants for the remaining Warrant Debt Securities after such exercise, and (iv) such other information as the Company or the [Senior] [Subordinated] Trustee shall reasonably
require. 
  
 (c) As soon as practicable after the exercise
of any Warrant, the Company shall issue, pursuant to the Indenture, in authorized denominations, to or upon the order of the holder of the Warrant Certificate evidencing such Warrant, the Warrant Debt Securities to which such holder is entitled, in
fully registered form, registered in such name or names as may be directed by such holder. If fewer than all of the Warrants evidenced by such Warrant Certificate are exercised, the Company shall execute, and an authorized officer of the Warrant
Agent shall manually countersign and deliver, a new Warrant Certificate evidencing Warrants for the number of Warrant Debt Securities remaining unexercised. 
  
 (d) The Company shall not be required to pay any stamp or other tax or other governmental charge required to be paid in connection with any
transfer involved in the issue of the Warrant Debt Securities, and in the event that any such transfer is involved, the Company shall not be required to issue or deliver any Warrant Debt Securities until such tax or other charge shall have been paid
or it has been established to the Company’s satisfaction that no such tax or other charge is due. 
  
 (e) Prior to the issuance of any Warrants there shall have been reserved, and the Company shall at all times through the Expiration Date keep
reserved, out of its authorized but unissued Warrant Debt Securities, a number of shares sufficient to provide for the exercise of the Warrants. 
  

 4. 

 ARTICLE 3 
  

OTHER PROVISIONS RELATING TO RIGHTS OF HOLDERS OF WARRANT 
 CERTIFICATES 
  
 3.1
No Rights As Holders of Warrant Debt Securities Conferred By Warrants or Warrant Certificates. No Warrant Certificate or Warrant evidenced thereby shall entitle the holder thereof to any of the rights of a holder of Warrant Debt
Securities, including, without limitation, the right to receive the payment of principal of (or premium, if any) or interest, if any, on the Warrant Debt Securities or to enforce any of the covenants in the Indenture. 
  
 3.2 Lost, Stolen, Mutilated or Destroyed Warrant Certificates.
Upon receipt by the Warrant Agent of evidence reasonably satisfactory to it and the Company of the ownership of and the loss, theft, destruction or mutilation of any Warrant Certificate and/or indemnity reasonably satisfactory to the Warrant Agent
and the Company and, in the case of mutilation, upon surrender of the mutilated Warrant Certificate to the Warrant Agent for cancellation, then, in the absence of notice to the Company or the Warrant Agent that such Warrant Certificate has been
acquired by a bona fide purchaser, the Company shall execute, and an authorized officer of the Warrant Agent shall manually countersign and deliver, in exchange for or in lieu of the lost, stolen, destroyed or mutilated Warrant Certificate, a new
Warrant Certificate of the same tenor and evidencing Warrants for a like principal amount of Warrant Debt Securities. Upon the issuance of any new Warrant Certificate under this Section 3.2, the Company may require the payment of a sum sufficient to
cover any tax or other governmental charge that may be imposed in relation thereto and any other expenses (including the fees and expenses of the Warrant Agent) in connection therewith. Every substitute Warrant Certificate executed and delivered
pursuant to this Section 3.2 in lieu of any lost, stolen or destroyed Warrant Certificate shall represent an additional contractual obligation of the Company, whether or not the lost, stolen or destroyed Warrant Certificate shall be at any time
enforceable by anyone, and shall be entitled to the benefits of this Agreement equally and proportionately with any and all other Warrant Certificates duly executed and delivered hereunder. The provisions of this Section 3.2 are exclusive and shall
preclude (to the extent lawful) all other rights and remedies with respect to the replacement of mutilated, lost, stolen or destroyed Warrant Certificates. 
  
 3.3 Holder Of Warrant Certificate May Enforce Rights. Notwithstanding any of the provisions of this Agreement, any holder of any Warrant
Certificate, without the consent of the Warrant Agent, the [Senior] [Subordinated] Trustee, the holder of any Warrant Debt Securities or the holder of any other Warrant Certificate, may, in such holder’s own behalf and for such holder’s
own benefit, enforce, and may institute and maintain any suit, action or proceeding against the Company suitable to enforce, or otherwise in respect of, such holder’s right to exercise the Warrants evidenced by such holder’s Warrant
Certificate in the manner provided in such holder’s Warrant Certificates and in this Agreement. 
  
 3.4 Merger, Sale, Conveyance or Lease. In case of (a) any share exchange, merger or similar transaction of the Company with or into another
person or entity (other than a share exchange, merger or similar transaction in which the Company is the acquiring or surviving corporation) or (b) the sale, exchange, lease, transfer or other disposition of all or substantially all of the
properties and assets of the Company as an entirety (in any such case, a “REORGANIZATION EVENT”), then, as a condition of such Reorganization Event, lawful 
  

 5. 

 provisions shall be made, and duly executed documents evidencing the same from the Company’s successor shall be
delivered to the holders of the Warrants, so that such successor shall succeed to and be substituted for the Company, and assume all the Company’s obligations under, this Agreement and the Warrants. The Company shall thereupon be relieved of
any further obligation hereunder or under the Warrants, and the Company as the predecessor corporation may thereupon or at any time thereafter be dissolved, wound up or liquidated. Such successor or assuming entity thereupon may cause to be signed,
and may issue either in its own name or in the name of the Company, any or all of the Warrants issuable hereunder which heretofore shall not have been signed by the Company, and may execute and deliver securities in its own name, in fulfillment of
its obligations to deliver Warrant Debt Securities upon exercise of the Warrants. All the Warrants so issued shall in all respects have the same legal rank and benefit under this Agreement as the Warrants theretofore or thereafter issued in
accordance with the terms of this Agreement as though all of such Warrants had been issued at the date of the execution hereof. In any case of any such Reorganization Event, such changes in phraseology and form (but not in substance) may be made in
the Warrants thereafter to be issued as may be appropriate. 
  
 The Warrant Agent may receive a written opinion of legal counsel as conclusive evidence that any such Reorganization Event complies with the provisions of this Section 3.4. 
  
 3.5 Notice To Warrantholders. In case the Company shall (a) effect any Reorganization Event or (b) make any
distribution on or in respect of the [title of Warrant Debt Securities] in connection with the dissolution, liquidation or winding up of the Company, then the Company shall mail to each holder of Warrants at such holder’s address as it shall
appear on the books of the Warrant Agent, at least ten days prior to the applicable date hereinafter specified, a notice stating the date on which such Reorganization Event, dissolution, liquidation or winding up is expected to become effective, and
the date as of which it is expected that holders of [title of Warrant Debt Securities] of record shall be entitled to exchange their shares of [title of Warrant Debt Securities] for securities or other property deliverable upon such Reorganization
Event, dissolution, liquidation or winding up. No failure to mail such notice nor any defect therein or in the mail in thereof shall affect any such transaction. 
  
 ARTICLE 4 
  
 EXCHANGE AND TRANSFER OF WARRANT CERTIFICATES 
  
 4.1 Exchange and Transfer of Warrant Certificates. [If Other Securities with Warrants which are immediately detachable—Upon] [If Other
Securities with Warrants which are not immediately detachable—Prior to the Detachable Date, a Warrant Certificate may be exchanged or transferred only together with the Other Security to which the Warrant Certificate was initially attached, and
only for the purpose of effecting or in conjunction with an exchange or transfer of such Other Security. Prior to any Detachable Date, each transfer of the Other Security shall operate also to transfer the related Warrant Certificates. After the
Detachable Date, upon] surrender at the corporate trust office of the Warrant Agent, Warrant Certificates evidencing Warrants may be exchanged for Warrant Certificates in other denominations evidencing such Warrants or the transfer thereof may be
registered in whole or in part; provided that such other Warrant Certificates evidence Warrants for the same aggregate principal amount of Warrant Debt Securities as the Warrant Certificates so surrendered. The Warrant Agent shall 
  

 6. 

 keep, at its corporate trust office, books in which, subject to such reasonable regulations as it may prescribe, it shall
register Warrant Certificates and exchanges and transfers of outstanding Warrant Certificates, upon surrender of the Warrant Certificates to the Warrant Agent at its corporate trust office for exchange or registration of transfer, properly endorsed
or accompanied by appropriate instruments of registration of transfer and written instructions for transfer, all in form satisfactory to the Company and the Warrant Agent. No service charge shall be made for any exchange or registration of transfer
of Warrant Certificates, but the Company may require payment of a sum sufficient to cover any stamp or other tax or other governmental charge that may be imposed in connection with any such exchange or registration of transfer. Whenever any Warrant
Certificates are so surrendered for exchange or registration of transfer, an authorized officer of the Warrant Agent shall manually countersign and deliver to the person or persons entitled thereto a Warrant Certificate or Warrant Certificates duly
authorized and executed by the Company, as so requested. The Warrant Agent shall not be required to effect any exchange or registration of transfer which will result in the issuance of a Warrant Certificate evidencing a Warrant for a fraction of a
Warrant Debt Security or a number of Warrants for a whole number of Warrant Debt Securities and a fraction of a Warrant Debt Security. All Warrant Certificates issued upon any exchange or registration of transfer of Warrant Certificates shall be the
valid obligations of the Company, evidencing the same obligations and entitled to the same benefits under this Agreement as the Warrant Certificate surrendered for such exchange or registration of transfer. 
  
 4.2 Treatment of Holders of Warrant Certificates. [If Other
Securities and Warrants are not immediately detachable—Prior to the Detachable Date, the Company, the Warrant Agent and all other persons may treat the owner of the Other Security as the owner of the Warrant Certificates initially attached
thereto for any purpose and as the person entitled to exercise the rights represented by the Warrants evidenced by such Warrant Certificates, any notice to the contrary notwithstanding. After the Detachable Date and prior to due presentment of a
Warrant Certificate for registration of transfer, the] [The] Company, the Warrant Agent and all other persons may treat the registered holder of a Warrant Certificate as the absolute owner thereof for any purpose and as the person entitled to
exercise the rights represented by the Warrants evidenced thereby, any notice to the contrary notwithstanding. 
  
 4.3 Cancellation of Warrant Certificates. Any Warrant Certificate surrendered for exchange, registration of transfer or exercise of the
Warrants evidenced thereby shall, if surrendered to the Company, be delivered to the Warrant Agent and all Warrant Certificates surrendered or so delivered to the Warrant Agent shall be promptly canceled by the Warrant Agent and shall not be
reissued and, except as expressly permitted by this Agreement, no Warrant Certificate shall be issued hereunder in exchange therefor or in lieu thereof. The Warrant Agent shall deliver to the Company from time to time or otherwise dispose of
canceled Warrant Certificates in a manner satisfactory to the Company. 
  
 ARTICLE 5 
  
 CONCERNING THE WARRANT AGENT

  
 5.1 Warrant Agent. The Company hereby
appoints                      as Warrant Agent of the Company in respect of the Warrants and the Warrant Certificates upon the terms and

  

 7. 

 subject to the conditions herein set forth, and
                     hereby accepts such appointment. The Warrant Agent shall have the powers and authority granted to and conferred upon it
in the Warrant Certificates and hereby and such further powers and authority to act on behalf of the Company as the Company may hereafter grant to or confer upon it. All of the terms and provisions with respect to such powers and authority contained
in the Warrant Certificates are subject to and governed by the terms and provisions hereof. 
  
 5.2 Conditions of Warrant Agent’s Obligations. The Warrant Agent accepts its obligations herein set forth upon the terms and conditions hereof, including the following to all of which the Company
agrees and to all of which the rights hereunder of the holders from time to time of the Warrant Certificates shall be subject: 
  
 (a) Compensation and Indemnification. The Company agrees promptly to pay the Warrant Agent the compensation to be agreed upon with the
Company for all services rendered by the Warrant Agent and to reimburse the Warrant Agent for reasonable out-of-pocket expenses (including reasonable counsel fees) incurred without negligence, bad faith or willful misconduct by the Warrant Agent in
connection with the services rendered hereunder by the Warrant Agent. The Company also agrees to indemnify the Warrant Agent for, and to hold it harmless against, any loss, liability or expense incurred without negligence, bad faith or willful
misconduct on the part of the Warrant Agent, arising out of or in connection with its acting as Warrant Agent hereunder, including the reasonable costs and expenses of defending against any claim of such liability. 
  
 (b) Agent for the Company. In acting under this Warrant
Agreement and in connection with the Warrant Certificates, the Warrant Agent is acting solely as agent of the Company and does not assume any obligations or relationship of agency or trust for or with any of the holders of Warrant Certificates or
beneficial owners of Warrants. 
  
 (c) Counsel. The
Warrant Agent may consult with counsel satisfactory to it, which may include counsel for the Company, and the written advice of such counsel shall be full and complete authorization and protection in respect of any action taken, suffered or omitted
by it hereunder in good faith and in accordance with the advice of such counsel. 
  
 (d) Documents. The Warrant Agent shall be protected and shall incur no liability for or in respect of any action taken or omitted by it in reliance upon any Warrant Certificate, notice, direction,
consent, certificate, affidavit, statement or other paper or document reasonably believed by it to be genuine and to have been presented or signed by the proper parties. 
  
 (e) Certain Transactions. The Warrant Agent, and its officers, directors and employees, may become the owner
of, or acquire any interest in, Warrants, with the same rights that it or they would have if it were not the Warrant Agent hereunder, and, to the extent permitted by applicable law, it or they may engage or be interested in any financial or other
transaction with the Company and may act on, or as depositary, trustee or agent for, any committee or body of holders of Warrant Debt Securities or other obligations of the Company as freely as if it were not the Warrant Agent hereunder. Nothing in
this Warrant Agreement shall be deemed to prevent the Warrant Agent from acting as [Senior] [Subordinated] Trustee under the [Senior] [Subordinated] Indenture. 
  

 8. 

 (f) No Liability for Interest. Unless otherwise agreed with the Company, the Warrant Agent
shall have no liability for interest on any monies at any time received by it pursuant to any of the provisions of this Agreement or of the Warrant Certificates. 
  
 (g) No Liability for Invalidity. The Warrant Agent shall have no liability with respect to any invalidity of
this Agreement or any of the Warrant Certificates (except as to the Warrant Agent’s countersignature thereon). 
  
 (h) No Responsibility for Representations. The Warrant Agent shall not be responsible for any of the recitals or representations herein or
in the Warrant Certificates (except as to the Warrant Agent’s countersignature thereon), all of which are made solely by the Company. 
  
 (i) No Implied Obligations. The Warrant Agent shall be obligated to perform only such duties as are herein and in the Warrant Certificates
specifically set forth and no implied duties or obligations shall be read into this Agreement or the Warrant Certificates against the Warrant Agent. The Warrant Agent shall not be under any obligation to take any action hereunder which may tend to
involve it in any expense or liability, the payment of which within a reasonable time is not, in its reasonable opinion, assured to it. The Warrant Agent shall not be accountable or under any duty or responsibility for the use by the Company of any
of the Warrant Certificates authenticated by the Warrant Agent and delivered by it to the Company pursuant to this Agreement or for the application by the Company of the proceeds of the Warrant Certificates. The Warrant Agent shall have no duty or
responsibility in case of any default by the Company in the performance of its covenants or agreements contained herein or in the Warrant Certificates or in the case of the receipt of any written demand from a holder of a Warrant Certificate with
respect to such default, including, without limiting the generality of the foregoing, any duty or responsibility to initiate or attempt to initiate any proceedings at law or otherwise or, except as provided in Section 6.2 hereof, to make any demand
upon the Company. 
  
 5.3 Resignation, Removal and Appointment
of Successors. 
  
 (a) The Company agrees, for the
benefit of the holders from time to time of the Warrant Certificates, that there shall at all times be a Warrant Agent hereunder until all the Warrants have been exercised or are no longer exercisable. 
  
 (b) The Warrant Agent may at any time resign as agent by giving
written notice to the Company of such intention on its part, specifying the date on which its desired resignation shall become effective; provided that such date shall not be less than three months after the date on which such notice is given unless
the Company otherwise agrees. The Warrant Agent hereunder may be removed at any time by the filing with it of an instrument in writing signed by or on behalf of the Company and specifying such removal and the intended date when it shall become
effective. Such resignation or removal shall take effect upon the appointment by the Company, as hereinafter provided, of a successor Warrant Agent (which shall be a bank or trust company authorized under the laws of the jurisdiction of its
organization to exercise corporate trust powers) and the acceptance of such appointment by such successor Warrant Agent. The obligation of the Company under Section 5.2(a) shall continue to the extent set forth therein notwithstanding the
resignation or removal of the Warrant Agent. 
  

 9. 

 (c) In case at any time the Warrant Agent shall resign, or shall be removed, or shall become
incapable of acting, or shall be adjudged a bankrupt or insolvent, or shall commence a voluntary case under the Federal bankruptcy laws, as now or hereafter constituted, or under any other applicable Federal or state bankruptcy, insolvency or
similar law or shall consent to the appointment of or taking possession by a receiver, custodian, liquidator, assignee, trustee, sequestrator (or other similar official) of the Warrant Agent or its property or affairs, or shall make an assignment
for the benefit of creditors, or shall admit in writing its inability to pay its debts generally as they become due, or shall take corporate action in furtherance of any such action, or a decree or order for relief by a court having jurisdiction in
the premises shall have been entered in respect of the Warrant Agent in an involuntary case under the Federal bankruptcy laws, as now or hereafter constituted, or any other applicable Federal or state bankruptcy, insolvency or similar law, or a
decree or order by a court having jurisdiction in the premises shall have been entered for the appointment of a receiver, custodian, liquidator, assignee, trustee, sequestrator (or similar official) of the Warrant Agent or of its property or
affairs, or any public officer shall take charge or control of the Warrant Agent or of its property or affairs for the purpose of rehabilitation, conservation, winding up or liquidation, a successor Warrant Agent, qualified as aforesaid, shall be
appointed by the Company by an instrument in writing, filed with the successor Warrant Agent. Upon the appointment as aforesaid of a successor Warrant Agent and acceptance by the successor Warrant Agent of such appointment, the Warrant Agent shall
cease to be Warrant Agent hereunder. 
  
 (d) Any successor
Warrant Agent appointed hereunder shall execute, acknowledge and deliver to its predecessor and to the Company an instrument accepting such appointment hereunder, and thereupon such successor Warrant Agent, without any further act, deed or
conveyance, shall become vested with all the authority, rights, powers, trusts, immunities, duties and obligations of such predecessor with like effect as if originally named as Warrant Agent hereunder, and such predecessor, upon payment of its
charges and disbursements then unpaid, shall thereupon become obligated to transfer, deliver and pay over, and such successor Warrant Agent shall be entitled to receive, all monies, securities and other property on deposit with or held by such
predecessor, as Warrant Agent hereunder. 
  
 (e) Any
corporation into which the Warrant Agent hereunder may be merged or converted or any corporation with which the Warrant Agent may be consolidated, or any corporation resulting from any merger, conversion or consolidation to which the Warrant Agent
shall be a party, or any corporation to which the Warrant Agent shall sell or otherwise transfer all or substantially all the assets and business of the Warrant Agent, provided that it shall be qualified as aforesaid, shall be the successor Warrant
Agent under this Agreement without the execution or filing of any paper or any further act on the part of any of the parties hereto. 
  

 10. 

 ARTICLE 6 
  

MISCELLANEOUS 
  
 6.1 Amendment. This Agreement may be amended by the parties hereto, without the consent of the holder of any Warrant Certificate, for the
purpose of curing any ambiguity, or of curing, correcting or supplementing any defective provision contained herein, or making any other provisions with respect to matters or questions arising under this Agreement as the Company and the Warrant
Agent may deem necessary or desirable; provided that such action shall not materially adversely affect the interests of the holders of the Warrant Certificates. 
  

6.2 Notices and Demands to the Company and Warrant Agent. If the Warrant Agent shall receive any notice or demand addressed to the
Company by the holder of a Warrant Certificate pursuant to the provisions of the Warrant Certificates, the Warrant Agent shall promptly forward such notice or demand to the Company. 
  
 6.3 Addresses. Any communication from the Company to the Warrant Agent with respect to this Agreement shall be
addressed to                 , Attention:                 
and any communication from the Warrant Agent to the Company with respect to this Agreement shall be addressed to Tercica, Inc., 2000 Sierra Point Parkway, Suite 400, Brisbane, California 94005, Attention: General Counsel (or such other address as
shall be specified in writing by the Warrant Agent or by the Company). 
  
 6.4 Governing Law. This Agreement and each Warrant Certificate issued hereunder shall be governed by and construed in accordance with the laws of the State of
[                ]. 
  
 6.5 Delivery Of Prospectus. The Company shall furnish to the Warrant Agent sufficient copies of a prospectus meeting the requirements of the
Securities Act of 1933, as amended, relating to the Warrant Debt Securities deliverable upon exercise of the Warrants (the “Prospectus”), and the Warrant Agent agrees that upon the exercise of any Warrant, the Warrant Agent will deliver to
the holder of the Warrant Certificate evidencing such Warrant, prior to or concurrently with the delivery of the Warrant Debt Securities issued upon such exercise, a Prospectus. The Warrant Agent shall not, by reason of any such delivery, assume any
responsibility for the accuracy or adequacy of such Prospectus. 
  
 6.6 Obtaining of Governmental Approvals. The Company will from time to time take all action which may be necessary to obtain and keep effective any and all permits, consents and approvals of governmental agencies and
authorities and securities act filings under United States Federal and state laws (including without limitation a registration statement in respect of the Warrants and Warrant Debt Securities under the Securities Act of 1933, as amended), which may
be or become requisite in connection with the issuance, sale, transfer, and delivery of the Warrant Debt Securities issued upon exercise of the Warrants, the issuance, sale, transfer and delivery of the Warrants or upon the expiration of the period
during which the Warrants are exercisable. 
  
 6.7
Persons Having Rights Under Warrant Agreement. Nothing in this Agreement shall give to any person other than the Company, the Warrant Agent and the holders of the Warrant Certificates any right, remedy or claim under or by reason of this
Agreement. 
  
 6.8 Headings. The descriptive
headings of the several Articles and Sections of this Agreement are inserted for convenience only and shall not control or affect the meaning or construction of any of the provisions hereof. 
  

 11. 

 6.9 Counterparts. This Agreement may be executed in any number of counterparts, each of
which as so executed shall be deemed to be an original, but such counterparts shall together constitute but one and the same instrument. 
  
 6.10 Inspection of Agreement. A copy of this Agreement shall be available at all reasonable times at the principal corporate trust office of
the Warrant Agent for inspection by the holder of any Warrant Certificate. The Warrant Agent may require such holder to submit his Warrant Certificate for inspection by it. 
  
 IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be
duly executed, all as of the day and year first above written. 
  

					
	 	  	TERCICA, INC.
			
	 	  	 By
	  	  

			
	 	  	 Its
	  	  

			
	 Attest:
	  	 	  	 
			
	  

	  	 	  	 
			
	  

	  	 	  	 
		
	 	  	  
 Warrant
Agent

			
	 	  	 By
	  	  

			
	 	  	 Its
	  	  

			
	 Attest:
	  	 	  	 
			
	  

	  	 	  	 
			
	  

	  	 	  	 

  
 [SIGNATURE PAGE TO DEBT
SECURITIES WARRANT AGREEMENT] 
  

 12. 

 EXHIBIT A 
  

FORM OF WARRANT CERTIFICATE 
 [FACE
OF WARRANT CERTIFICATE] 
  

			
	[[Form if Warrants are attached to Other Securities and are not immediately detachable.]	  	[Prior to                     , this Warrant Certificate cannot be transferred or
exchanged unless attached to a [Title of Other Securities].]
		
	[Form of Legend if Warrants are not immediately exercisable.]	  	[Prior to                     , Warrants evidenced by this Warrant Certificate cannot
be exercised.]

  
 EXERCISABLE ONLY IF
COUNTERSIGNED BY THE WARRANT AGENT AS 
 PROVIDED HEREIN 
  
 VOID AFTER [            ] P.M., [CITY] TIME, ON
                    , 
  

 13. 

 TERCICA, INC. 
 WARRANT CERTIFICATE REPRESENTING 
 WARRANTS TO PURCHASE 
 [TITLE OF WARRANT DEBT SECURITIES] 
  

	 No.                               
	 Warrants 

  
 This certifies that                     
or registered assigns is the registered owner of the above indicated number of Warrants, each Warrant entitling such owner [If Warrants are attached to Other Securities and are not immediately detachable —, subject to the registered owner
qualifying as a “Holder” of this Warrant Certificate, as hereinafter defined)] to purchase, at any time [after [            ] p.m., [City] time, on
                     and] on or before [            ] p.m., [City] time, on
                    , $             principal amount of [Title of
Warrant Debt Securities] (the “Warrant Debt Securities”), of Tercica, Inc. (the “Company”), issued or to be issued under the Indenture (as hereinafter defined), on the following basis: during the period from
                    , through and including
                    , each Warrant shall entitle the Holder thereof, subject to the provisions of this Agreement, to purchase the
principal amount of Warrant Debt Securities stated in the Warrant Certificate at the warrant price (the “Warrant Price”) of             % of the principal amount
thereof [plus accrued amortization, if any, of the original issue discount of the Warrant Debt Securities] [plus accrued interest, if any, from the most recent date from which interest shall have been paid on the Warrant Debt Securities or, if no
interest shall have been paid on the Warrant Debt Securities, from the date of their original issuance]. [The original issue discount ($             for each $1,000 principal amount
of Warrant Debt Securities) will be amortized at a             % annual rate, computed on a[n] [semi-]annual basis [using a 360-day year consisting of twelve 30-day months].
The Holder may exercise the Warrants evidenced hereby by providing certain information set forth on the back hereof and by paying in full, in lawful money of the United States of America, [in cash or by certified check or official bank check in New
York Clearing House funds] [by bank wire transfer in immediately available funds], the Warrant Price for each Warrant Debt Security with respect to which this Warrant is exercised to the Warrant Agent (as hereinafter defined) and by surrendering
this Warrant Certificate, with the purchase form on the back hereof duly executed, at the corporate trust office of [name of Warrant Agent], or its successor as warrant agent (the “Warrant Agent”), which is, on the date hereof, at the
address specified on the reverse hereof, and upon compliance with and subject to the conditions set forth herein and in the Warrant Agreement (as hereinafter defined). 
  
 The term “Holder” as used herein shall mean [If Warrants are attached to Other Securities and are not immediately
detachable—, prior to                     ,             
(the “Detachable Date”), the registered owner of the Company’s [title of Other Securities] to which this Warrant Certificate was initially attached, and after such Detachable Date,] the person in whose name at the time this
Warrant Certificate shall be registered upon the books to be maintained by the Warrant Agent for that purpose pursuant to Section 4 of the Warrant Agreement. 
  
 The Warrants evidenced by this Warrant Certificate may be exercised to purchase Warrant Debt Securities in the principal amount of $1,000 or any integral
multiple thereof in registered form. Upon any exercise of fewer than all of the Warrants evidenced by this Warrant Certificate, there shall be issued to the Holder hereof a new Warrant Certificate evidencing Warrants for the aggregate principal
amount of Warrant Debt Securities remaining unexercised. 
  

 14. 

 This Warrant Certificate is issued under and in accordance with the Warrant Agreement dated as of
                    ,              (the “Warrant
Agreement”), between the Company and the Warrant Agent and is subject to the terms and provisions contained in the Warrant Agreement, to all of which terms and provisions the Holder of this Warrant Certificate consents by acceptance hereof.
Copies of the Warrant Agreement are on file at the above-mentioned office of the Warrant Agent. 
  
 The Warrant Debt Securities to be issued and delivered upon the exercise of Warrants evidenced by this Warrant Certificate will be issued under and in
accordance with an Indenture, [dated as of                     ,
             (the “Senior Indenture”), between the Company and
                    , as trustee (such trustee, and any successors to such trustee, the “Senior Trustee”)] [dated as of
                    ,
                    , (the “Subordinated Indenture”), between the Company and
                                       
 , as trustee (such trustee, and any successors to such trustee, the “Subordinated Trustee”)] and will be subject to the terms and provisions contained in the Warrant Debt Securities and in the Indenture. Copies of the [Senior]
[Subordinated] Indenture, including the form of the Warrant Debt Securities, are on file at the corporate trust office of the Trustee. 
  
 [If Warrants are attached to Other Securities and are not immediately detachable—Prior to the Detachable Date, this Warrant Certificate may be
exchanged or transferred only together with the [Title of Other Securities] (the “OTHER SECURITIES”) to which this Warrant Certificate was initially attached, and only for the purpose of effecting or in conjunction with, an exchange or
transfer of such Other Security. Additionally, on or prior to the Detachable Date, each transfer of such Other Security on the register of the Other Securities shall operate also to transfer this Warrant Certificate. After such date, transfer of
this] [If Warrants are attached to Other Securities and are immediately detachable—Transfer of this] Warrant Certificate may be registered when this Warrant Certificate is surrendered at the corporate trust office of the Warrant Agent by the
registered owner or such owner’s assigns, in the manner and subject to the limitations provided in the Warrant Agreement. 
  
 [If Other Securities with Warrants which are not immediately detachable-Except as provided in the immediately preceding paragraph, after] [If Other
Securities with Warrants which are immediately detachable or Warrants alone—After] countersignature by the Warrant Agent and prior to the expiration of this Warrant Certificate, this Warrant Certificate may be exchanged at the corporate trust
office of the Warrant Agent for Warrant Certificates representing Warrants for the same aggregate principal amount of Warrant Debt Securities. 
  
 This Warrant Certificate shall not entitle the Holder hereof to any of the rights of a holder of the Warrant Debt Securities, including, without
limitation, the right to receive payments of principal of (and premium, if any) or interest, if any, on the Warrant Debt Securities or to enforce any of the covenants of the Indenture. 
  

 15. 

 Reference is hereby made to the further provisions of this Warrant Certificate set forth on the reverse
hereof, which further provisions shall for all purposes have the same effect as if set forth at this place. 
  
 This Warrant Certificate shall not be valid or obligatory for any purpose until countersigned by the Warrant Agent. 
  
 IN WITNESS WHEREOF, the
Company has caused this Warrant to be executed in its name and on its behalf by the facsimile signatures of its duly authorized officers. 
  
 Dated:                                     
             
  

							
				
	 	 	 	 	 	 	TERCICA, INC.
				
	 	 	 	 	By	 	  

				
	 	 	 	 	Its	 	  

	Attest:	 	 	 	 	 	 
		
	  

	 	 
		
	 	 	Countersigned:
				
	 	 	 	 	 	 	  

 As Warrant
Agent

				
	 	 	 	 	By	 	  

	 	 	 	 	 	 	Authorized Signature

  

 16. 

 [REVERSE OF WARRANT CERTIFICATE] 
  
 (Instructions for Exercise of Warrant) 
  
 To exercise any Warrants evidenced hereby for Warrant Debt Securities (as hereinafter defined), the Holder must pay, in
lawful money of the United States of America, [in cash or by certified check or official bank check in New York Clearing House funds] [by bank wire transfer in immediately available funds], the Warrant Price in full for Warrants exercised, to
[Warrant Agent] [address of Warrant Agent], Attn:                     , which payment must specify the name of the Holder and the
number of Warrants exercised by such Holder. In addition, the Holder must complete the information required below and present this Warrant Certificate in person or by mail (certified or registered mail is recommended) to the Warrant Agent at the
appropriate address set forth above. This Warrant Certificate, completed and duly executed, must be received by the Warrant Agent within five business days of the payment. 
  
 (To be executed upon exercise of Warrants) 
  
 The undersigned hereby irrevocably elects to exercise
                     Warrants, represented by this Warrant Certificate, to purchase
$             principal amount of the [Title of Warrant Debt Securities] (the “Warrant Debt Securities”) of Tercica, Inc. and represents that he has tendered payment for
such Warrant Debt Securities, in lawful money of the United States of America, [in cash or by certified check or official bank check in New York Clearing House funds] [by bank wire transfer in immediately available funds], to the order of Tercica,
Inc., c/o [insert name and address of Warrant Agent], in the amount of $             in accordance with the terms hereof. The undersigned requests that said principal amount of
Warrant Debt Securities be in fully registered form in the authorized denominations, registered in such names and delivered all as specified in accordance with the instructions set forth below. 
  
 If the number of Warrants exercised is less than all the Warrants evidenced
hereby, the undersigned requests that a new Warrant Certificate evidencing the Warrants for the aggregate principal amount of Warrant Debt Securities remaining unexercised be issued and delivered to the undersigned unless otherwise specified in the
instructions below. 
  

							
	Dated	 	  

	    	Name	 	  

	 	 	 	    	 	 	Please Print
				
	Address:	 	  

	    	 	 	 
			
	  

	    	 	 	 
			
	  

	    	 	 	 

 (Insert Social Security or Other Identifying Number of Holder) 
  

			
	 Signature Guaranteed
	 	  

	 	 	Signature

  

 17. 

 (Signature must conform in all respects to name of holder as specified on the face of this Warrant Certificate and must
bear a signature guarantee by a bank, trust company or member broker of the New York, Midwest or Pacific Stock Exchange). 
  
 This Warrant may be exercised at the following addresses: 
  

					
	By hand at	 	  

	 	 
		
	  

	 	 
		
	  

	 	 
			
	By mail at	 	  

	 	 
		
	  

	 	 
		
	  

	 	 

  
 [Instructions as to form and delivery
of Warrant Debt Securities and, if applicable, Warrant Certificates evidencing Warrants for the number of Warrant Debt Securities remaining unexercised—complete as appropriate.] 
  

 18. 

 ASSIGNMENT 
  

[Form of assignment to be executed if Warrant Holder desires to transfer Warrant) 
  
 FOR VALUE RECEIVED,
                             hereby sells, assigns and transfers unto: 
  

			
		
	  

	 	 
		
	  

	 	 
		
	  

 (Please
print name and address including zip code)
	 	  

   Please
print Social Security or other identifying number

  
 the right represented by the within
Warrant to purchase $             aggregate principal amount of [Title of Warrant Debt Securities] of Tercica, Inc. to which the within Warrant relates and appoints
                     attorney to transfer such right on the books of the Warrant Agent with full power of substitution in the premises.

  

					
	 Dated
	  	  

	  	  

	 	  	 	  	Signature

  
 (Signature must conform in all
respects to name of holder as specified on the face of the Warrant) 
  
 Signature
Guaranteed 
  

  

 19.Employment Agreement

 Exhibit 10.1 
  
 EMPLOYMENT AGREEMENT 
  
 This Agreement is entered into as of this 9th day of September, 2005 (the “Effective Date”), between Newmont USA Limited (“Newmont”)
and David H. Francisco (the “Executive”). 
  
 RECITALS

  
 WHEREAS, Newmont desires that the Executive perform
services as set forth in this Agreement; 
  
 WHEREAS, the
Executive desires to perform these services for Newmont under the terms and conditions set forth in this Agreement; 
  
 WHEREAS, the Executive and Newmont wish to terminate the Employment Agreement by and between the Executive and Newmont Mining Corporation dated
February 1, 1999 and any other agreements entered into by the Executive and Newmont or any of its affiliates as of the date hereof, except as set forth below. 
  
 In consideration of the mutual promises set forth herein, it is agreed by and between Newmont and the Executive: 

 
 1. Revocation of Prior Agreements. The Employment Agreement
dated February 1, 1999 by and between the Executive and Newmont Mining Corporation, any amendments thereto and any other written or oral agreements between the Executive and Newmont, Newmont Mining Corporation or their affiliates are hereby
terminated and revoked and shall have no effect as of the Effective Date. 
  
 2. Description of Work. The Executive hereby resigns as an officer of Newmont Mining Corporation and as an officer or director of any of its affiliates other than Newmont Technologies Limited. The
Executive will continue as an executive employee of Newmont and shall serve as Chairman of Newmont Technologies Limited. The Executive shall be available upon the reasonable request of Newmont to consult with and advise Newmont with respect to its
business operations and practices. Newmont shall not be bound by any advice or consultation provided by the Executive. 
  
 3. Salary. Newmont shall pay the Executive an annual salary of $500,000.00 (less applicable taxes and deductions, including benefits
deductions) during the term of this Agreement in accordance with Newmont’s normal payroll practices. 
  
 4. Office Equipment. Newmont shall provide reasonable office equipment to the Executive, including a computer, computer access, a fax
machine and fax line, in order for the Executive to provide the services to Newmont from his primary residence. 
  
 5. Benefit Plans, Programs and Bonuses. The Executive shall not be eligible for the Severance Plan of Newmont and the Executive Change of
Control Plan of Newmont, and the 

 
Executive hereby waives all rights to any benefits which may be otherwise payable under such Plans. The Executive shall be eligible to participate in or
receive any benefits offered by Newmont to its eligible employees subject to the exclusions and limitations set forth in this Agreement. The Executive shall be eligible to receive a bonus payment under the Annual Incentive Compensation Payroll
Practice of Newmont (“AICP”) and the Employee Performance Incentive Compensation Payroll Practice of Newmont (“EPIP”) for calendar year 2005 (to be paid in 2006). After 2005, the Executive shall not be entitled to payments under
the AICP or the EPIP. As of the Effective Date, the Executive shall not be eligible to receive any other bonus or incentive compensation nor shall the Executive be eligible to receive any stock options or restricted stock grants. Upon termination of
this Agreement, Executive shall be eligible for retiree medical or other retirement benefits, if applicable, in accordance with the terms of the Corporation’s benefits plans. 
  
 6. Term. This Agreement shall commence on the Effective Date and shall continue in force through a period of
36 months unless earlier terminated by the Executive for any reason (including death) or by Newmont for “Cause” or upon a breach of this Agreement by the Executive. 
  
 For purposes of this Agreement, “Cause” means: 
  
 (a) the willful and continued failure of the Executive to perform substantially the Executive’s duties
with Newmont (other than any such failure resulting from incapacity due to physical or mental illness) or his failure to follow policies, directions or Newmont’s code of conduct, after a written demand for substantial performance is delivered
to the Executive by the Board of Directors of Newmont (the “Board”) or its delegate. Such written demand shall identify the manner in which the Board or its delegate believes that the Executive has not substantially performed the
Executive’s duties; or 
  
 (b) the engaging
by the Executive in illegal conduct or gross negligence or willful misconduct which is potentially injurious to Newmont or its affiliates; provided that if the Executive acts in accordance with an authorized written opinion of Newmont’s or an
affiliated entity’s legal counsel, such action will not constitute “Cause” under this definition; or 
  
 (c) any dishonest or fraudulent activity by the Executive or the reasonable belief by Newmont of the Executive’s breach of any
contract or agreement with Newmont or its affiliates. 
  
 In the
event “Cause” is determined to exist by the Board or its delegate or if the Executive breaches this Agreement as determined by the Board or its delegate, the Executive shall not be entitled to any further payments or benefits under this
Agreement. In the event the Executive terminates this Agreement for any reason (including death), the Executive shall not be entitled to any future payments or benefits under this Agreement. 
  
 Upon termination of this Agreement for any reason, the Executive shall no
longer be an employee of Newmont or any of its affiliates. 
  
 7.
Property of Newmont. All materials, ideas or other intellectual property created or 

 
developed by the Executive pursuant to the Executive’s services, or which the Executive may disclose to Newmont during the term hereof, shall be the
sole and absolute property of Newmont for any and all purposes whatsoever, and the Executive agrees that the Executive does not have, and shall not claim to have, any right, title or interest of any kind or nature whatsoever in or to such materials,
ideas or other property. Newmont may use and authorize others to use the Executive’s name and biographical material for publicity and promotional purposes. 
  

8. Executive Cooperation. The Executive agrees that he: (i) will assist in an orderly transition of his duties as a former officer
and employee of Newmont; (ii) will, to the extent that he is physically able to do so with the permission of his medical advisors and without receiving additional compensation, fully and completely cooperate with Newmont, both during and after
the period of employment, in all investigations and any pending or future litigation in which Newmont, its affiliates, employees, officers or directors is involved or may become involved; (iii) both during and after the period of employment
with Newmont, will not voluntarily cooperate with, or act as a witness, consultant or expert for, any person or party who is contemplating or bringing an action or proceeding of any kind adverse to Newmont, its affiliates, employees, officers or
directors; provided, however, that nothing herein shall preclude the Executive from cooperating with any investigation or inquiry by any agency of the United States or any state or subdivision thereof, or otherwise meeting any legal obligation to
provide testimony or other evidence in any action or proceeding; and (iv) will proactively assist in key employee retention efforts as directed by Newmont and support Newmont and its affiliates and his colleagues in a positive manner. The Board
or its delegate shall reasonably determine whether Executive has complied with the provisions of this section. 
  
 9. Non-Disparagement. The Executive further agrees that he will not, either verbally or in writing, make any public or private negative,
defamatory, disparaging, demeaning, or otherwise injurious statements concerning Newmont or its affiliates, employees, officers or directors in any manner whatsoever. Likewise, Newmont agrees that it will take reasonable efforts to ensure its
employees, officers and directors do not, either verbally or in writing, make defamatory, disparaging, demeaning, or otherwise injurious statements concerning the Executive in any manner whatsoever. 
  
 10. Confidentiality Agreement. The Executive
acknowledges that prior to and during the term of this Agreement, the Executive may acquire access to valuable and confidential information, trade secrets, and relationships with respect to Newmont’s successful business practices and operations
(“Confidential Information”). The Executive recognizes that Newmont has developed the Confidential Information through substantial expense and effort, that if disclosed Newmont considers the Confidential Information to be a significant
business advantage to Newmont’s competitors and potential competitors, and that the Confidential Information is a valuable, special and unique asset to Newmont’s business. The Executive understands that access to the Confidential
Information is restricted, that the Confidential Information is confidential, and that he may have access to the Confidential Information solely because of his relationship with Newmont. 
  
 The Executive acknowledges that it is reasonable and necessary for the protection of the goodwill and business of Newmont
that the Executive make the covenants and agreements contained in this section regarding conduct of the Executive during and subsequent to his employment with Newmont, and that Newmont shall suffer irreparable injury if the Executive engages in the

 
prohibited conduct. The covenants contained in this section shall survive the termination of this Agreement for any reason. In the event of a breach or
threatened breach by the Executive of the provisions of this section, Newmont shall be entitled to injunctive or other equitable relief enjoining and restraining the Executive from disclosing, in whole or in part, any such Confidential Information
and other remedies such as the recovery of damages from the Executive. 
  
 During the term of this Agreement, the Executive shall not, directly or indirectly, acquire, misappropriate, disclose to third persons or entities or use the Confidential Information except for purposes of performing the terms of this
Agreement. Upon termination of this Agreement, the Executive shall not, directly or indirectly, acquire, misappropriate, disclose to third persons or entities, or use the Confidential Information in any manner whatsoever. The Executive shall not
remove any documents, records or files belonging to Newmont from Newmont’s offices nor shall the Executive retain any copies of any documents, records, lists, files, or other information, maintained electronically or otherwise, containing or
reflecting the Confidential Information after the termination of this Agreement. 
  
 11. Non-Competition. Nothing in this Agreement shall preclude the Executive from engaging in business, charitable and community affairs, to the extent that such activities do not inhibit or prohibit the
performance of the Executive’s duties under this Agreement or conflict in any way with the business of Newmont or its affiliates. The Executive may also engage in personal investment opportunities, provided that (a) the Executive will not
devote any time to any business affairs or personal investment that would interfere or derogate from his employment with Newmont and (b) the Executive will not pursue or participate in a business affair or personal investment which creates, or
would create, a conflict of interest between the Executive and Newmont or which may adversely affect the good will of Newmont. The Executive shall avoid any situation in which his personal interest could conflict, or reasonably appear to conflict,
with the interests of Newmont, including opportunities for personal gain. Notwithstanding the foregoing, the Executive may engage in an enterprise for profit with consent of Wayne W. Murdy, Sharon Thomas or the Board, which consent shall not be
unreasonably delayed or denied. 
  
 12.
Non-Solicitation. During the term of the Agreement and for a period of one (1) year after its termination, the Executive agrees not to solicit to hire any employee of Newmont or its affiliates unless approved by Newmont.

  
 13. Breach. In the event of a breach of any of
the terms or conditions of this Agreement, this Agreement may be terminated by the offended party immediately. Any waiver of any breach of any provision shall not be deemed to be a waiver of any subsequent breach or of the provision itself. Should
litigation or other legal proceeding result from a breach of this Agreement the breaching party will be responsible for all costs and attorney’s fees associated therewith. 
  
 14. Newmont’s Right to Inspect Books and Records. Newmont shall, at all times, have access to all of the
Executive’s work product, production materials, books, records, correspondence, instructions, receipts, vouchers and memoranda of every description pertaining to the work done under this Agreement. 
  
 15. General Release of Claims. In exchange for, and in
consideration of, the payments, 

 
benefits, and other commitments described above, the Executive, for himself and for each of his heirs, executors, administrators, and assigns, hereby fully
releases, acquits and forever discharges Newmont and each of its predecessors, assigns, parent corporations, subsidiary corporations, affiliated corporations, and the officers, directors, shareholders, partners, employees, attorneys and agents past
and present, of each of the aforesaid entities (“Related Persons”) of and from any and all claims, liabilities, causes of action, demands to any rights, damages, costs, attorney’s fees, expenses, and compensation whatsoever, of
whatever kind or nature, in law, equity or otherwise, whether known or unknown, vested or contingent, suspected or unsuspected, that the Executive may now have, has ever had, or hereafter may have relating directly or indirectly to his employment
with Newmont prior to the Effective Date. The Executive releases any and all claims he may have that arose prior to the Effective Date, and hereby specifically waives and releases all claims, including, but not limited to, those arising under Title
VII of the Civil Rights Act of 1964, as amended, the Civil Rights Act of 1991, the Equal Pay Act, the Americans With Disabilities Act, Sections 1981 through 1988 of Title 42 of the United States Code, as amended, the Immigration Reform and Control
Act, as amended, the Workers Adjustment and Retraining Notification Act, as amended, the Occupational Safety and Health Act, as amended, the Sarbanes-Oxley Act of 2002, the Consolidated Omnibus Budget Reconciliation Act (COBRA), the Family and
Medical Leave Act, the National Labor Relations Act, the Fair Labor Standards Act, and any and all state or local statutes, ordinances, or regulations, as well as all claims arising under federal, state, or local law involving any tort, employment
contract (express or implied), public policy, wrongful discharge or any other claim. 
  
 Newmont, its predecessors, assigns, parent corporations, subsidiary corporations, affiliated corporations, officers, directors, shareholders, partners, employees and all agents, past and present (collectively, for
purposes of this paragraph, the “Newmont Releasors”), hereby fully release, acquit and forever discharge the Executive of and from any and all claims, liabilities, causes of action, demands to any rights, damages, costs, attorneys’
fees, expenses, and compensation whatsoever, of whatever kind or nature, in law, equity or otherwise, whether known or unknown, vested or contingent, suspected or unsuspected that the Newmont Releasors may now have, have ever had, or hereafter may
have relating directly or indirectly to the Executive’s employment with Newmont prior to the Effective Date. 
  
 16. Release of ADEA (Age) Claim. In exchange for, and in consideration of, the payments, benefits and other commitments described above, the
Executive, for himself and for each of his heirs, executors, administrators, and assigns, hereby fully releases, acquits and forever discharges Newmont and the Related Persons of and from any claim arising under the Age Discrimination in Employment
Act, as amended (ADEA), whether known or unknown, including any claims for attorney’s fees, expenses, and/or any compensation whatsoever, of whatever kind or nature, relating directly or indirectly to his employment with Newmont prior to the
Effective Date. 
  
 The Executive, being 40 years of age or older,
is advised of and acknowledges the following: 
  
 (a) Twenty-One Day Consideration Period. The Executive shall have up to 21 days to consider and accept the terms of this Agreement by fully executing and notarizing it below, and returning it to Newmont. During this 21-day period and
before signing this Agreement, the Executive is encouraged to consult with an attorney regarding the terms and 

 
provisions of this Agreement, at his own expense. The terms and provisions of this Agreement are null and void if not accepted by the Executive within the
21-day period. The Executive may sign the Agreement prior to the conclusion of the 21-day period. 
  
 (b) Release of Age Discrimination in Employment Act Claims. By signing this Agreement the Executive waives any claims he has
or might have against Newmont or the Related Persons under the ADEA that accrued prior to the Effective Date. 
  
 (c) Revocation Period. The Executive shall have 7 calendar days from the date he signs this Agreement to revoke the Agreement by
notifying Newmont in writing prior to the expiration of the 7-calendar day period. Any revocation within this period must state “I hereby revoke my acceptance of our Agreement and General Release.” The written revocation must be
hand-delivered to the Vice President of Human Resources, Newmont Mining Corporation, within 7 calendar days of the Executive’s execution of this Agreement. This Agreement shall not become effective or enforceable until the revocation period has
expired. If the last day of the revocation period is a Saturday, Sunday, or legal holiday, then the revocation period shall not expire until the next following day that is not a Saturday, Sunday, or legal holiday. 
  
 THE EXECUTIVE IS HEREBY ADVISED THAT HE HAS UP TO 21 CALENDAR DAYS TO
REVIEW AND CONSIDER THIS AGREEMENT AND IS HEREBY ADVISED IN WRITING TO CONSULT WITH AN ATTORNEY PRIOR TO EXECUTION OF THIS AGREEMENT. 
  
 THE EXECUTIVE AGREES THAT ANY MODIFICATIONS, MATERIAL OR OTHERWISE, MADE TO THIS AGREEMENT DO NOT RESTART OR AFFECT IN ANY MANNER THE ORIGINAL
21-CALENDAR DAY CONSIDERATION PERIOD. 
  
 HAVING ELECTED TO
EXECUTE THIS AGREEMENT TO FULFILL THE PROMISES AND TO RECEIVE THE SUMS AND BENEFITS UNDER THIS AGREEMENT, THE EXECUTIVE FREELY AND KNOWINGLY, AND AFTER DUE CONSIDERATION, ENTERS INTO THIS AGREEMENT AND RELEASE INTENDING TO WAIVE, SETTLE AND RELEASE
ANY CLAIM UNDER THE ADEA HE HAS OR MIGHT HAVE AGAINST NEWMONT ACCRUING PRIOR TO THE EFFECTIVE DATE OF THIS AGREEMENT. 
  
 17. No Assignment; Binding Effect. Newmont and the Executive represent and warrant that no person other than the signatories hereto had or
has any interest in the matters referred to in this Agreement, that Newmont and the Executive have the sole right and exclusive authority to execute this Agreement, and that Newmont and the Executive have not sold, assigned, transferred, conveyed,
or otherwise disposed of any claim, demand or legal right which is the subject of this Agreement. Newmont will ensure that its obligations under this Agreement and any agreements relating to awards of restricted stock or stock options will be
binding upon any successor entity in the event of a change in control of Newmont (as defined in the Executive Change of Control Plan of Newmont) or otherwise. 

 18. Provisions Separable. The provisions of this Agreement are independent of
and separable from each other, and no provision shall be rendered invalid or unenforceable by virtue of the fact that for any reason any other or others of them may be invalid or unenforceable in whole or in part. 
  
 19. Governing Law. This Agreement shall be governed by the laws
of the State of Colorado. 
  
 IN WITNESS WHEREOF, the parties have
executed this Agreement as of the date first above written. 
  

			
	 EXECUTIVE

	
	 /s/ David H. Francisco

	 David H. Francisco

	
	 NEWMONT USA LIMITED

		
	 By
	 	 Sharon E. Thomas

	 Its
	 	 Vice President and Secretary

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