Document:

Exhibit 10.7

 

EMPLOYMENT AGREEMENT 

 

This Employment Agreement (“Agreement”)
is made as of March 26, 2012 (the “Effective Date”) between Response Genetics, Inc., a Delaware Corporation (the “Company”)
and Stephanie H. Astrow (“Executive”). In consideration of the promises and mutual covenants set forth below, the parties
agree as follows:

 

1.Duties.

 

1.1Executive shall serve as Vice President
of Research and Development (“VP of R&D”) of the Company and shall have all such authority, duties and responsibilities
as are consistent with such position and shall perform such other duties and responsibilities on behalf of the Company as reasonably
may be assigned to Executive by the Chief Executive Officer and/or the Company’s Board of Directors (“Board”).

 

1.2Executive shall report to the Chief
Executive Officer. It is understood that Executive shall devote substantially all of her time to her duties and responsibilities
as VP of R&D. Executive agrees to use her best efforts and devote her time, attention, skill and efforts to rendering her services
to further the best interests and welfare of the Company.

 

1.3The parties acknowledge that the Company’s
main offices are located in Los Angeles, California, which is Executive’s principal place of employment. Executive acknowledges
that she may be required to travel in connection with her employment.

 

1.4Extracurricular Activities.
It is recognized that participation by Executive in various professional, governmental, civic, charitable, educational and cultural
activities, other than those conducted by the Company, benefits the Company’s public image and Executive shall be free to
engage in such reasonable activities, provided that such activities do not conflict or otherwise compete with activities conducted
by the Company. Any such activities of significance shall be reported by Executive to the Company’s Chief Executive Officer
and Board of Directors.

 

2.Term.

 

2.1 The term of Executive’s employment
hereunder shall commence on the Effective Date and shall end on March 26, 2013 (the “Initial Term”), unless earlier
terminated as provided in Section 4 hereof; provided, however, that, unless earlier terminated as provided in Section 4 hereof,
the Initial Term shall automatically be extended for one additional year (the “Renewal Term”), and on each subsequent
anniversary, the Renewal Term shall be extended for one additional year (the period consisting of the Initial Term and the Renewal
Term (including extensions thereof) being referred to as the “Employment Period”), unless at least sixty (60) days
prior to the applicable anniversary date, the Company or Executive shall have given written notice to the other not to extend the
Employment Period. Nothing in this Section 2 shall limit the right of the Company or Executive to terminate Executive’s employment
hereunder on the terms and conditions set forth in Section 4 hereof.

 

3.Compensation and Benefits.

 

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3.1Base Salary. During the Employment
Period, Executive shall be paid an annual base salary of $250,000 (“Base Salary”). The Base Salary shall be payable
in accordance with the Company’s normal payroll practices.

 

3.2Bonus. With respect to each
fiscal year or portion of a fiscal year of the Company ending during the Term, Executive shall be eligible to receive an annual
incentive bonus (“Annual Bonus”) as determined by the Chief Executive Officer and approved the Compensation Committee
of up to 35% of Base Salary (the “Target Annual Bonus”), with the actual Annual Bonus payable being based upon the
Company’s achievement of performance goals, as determined by the Chief Executive Officer and approved by the Board, and Executive’s
achievement of individual performance objectives for such fiscal year, as reasonably determined by the Company and communicated
to Executive. Any earned Annual Bonus shall be paid to Executive pursuant to the terms of the applicable incentive plan. Any Bonus
earned for year 2012 shall be pro-rated based on the number of days Executive has been employed with the Company.

 

3.3Benefits. During the Employment
Period, Executive shall be eligible to participate in all employee benefit plans and arrangements that are made available generally
to other similarly situated employees of the Company.

 

3.4Equity Awards. Upon joining
the Company, Executive shall receive 110,000 shares of Stock options vesting monthly over 48 months and subject to the terms and
conditions of such plans and any award agreement between the Company and Executive evidencing such awards.

 

Executive shall be eligible to participate
in the equity-based incentive plans of the Company and may receive awards thereunder, as determined by the Chief Executive Office
and approved by Compensation Committee from time to time and subject to the terms and conditions of such plans and any award agreement
between the Company and Executive evidencing such awards.

 

3.5Business Expenses. The
Company shall pay or reimburse Executive for ordinary and necessary reasonable expenses which Executive incurs during the Employment
Period in performing her duties under this Agreement in accordance with the Company’s expense reimbursement policy.

 

3.6Paid Time Off. During the Employment
Period, Executive shall accrue paid time off days per year, which shall accrue in accordance with the policies made available to
other similarly situated employees of the Company. Such paid time off shall be taken at such times and intervals as shall be determined
by Executive, subject to the business needs of the Company.

 

4. Termination of Employment.

 

4.1General. Executive’s employment
hereunder shall terminate during the Employment Period upon any of the following: (a) Executive’s death; (b) a termination
by the Company for Disability, defined for purposes of this Agreement as Executive’s inability to perform the essential functions
of her position, with or without reasonable accommodation, for six (6) consecutive months; (c) termination by the Company with
or without Cause; (d) a termination by Executive with or without Good Reason; and (e) a non-renewal of the Employment Period in
accordance with Section 2.

 

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4.2Notice of Termination. Any purported
termination of Executive’s employment (other than termination due to Executive’s death) shall be communicated by written
Notice of Termination delivered to the other party hereto in accordance with Section 11 hereof.

 

4.3Date of Termination. For purposes
of this Agreement, “Date of Termination” shall mean the following: (a) if Executive’s employment is terminated
by Executive’s death, the date of Executive’s death; (b) if Executive’s employment is terminated by the Company
for Disability, thirty (30) days after the Notice of Termination is given; (c) if Executive’s employment is terminated with
Cause, the date specified in the Notice of Termination (but no earlier than the date such Notice of Termination is given), subject
to Executive’s right to cure, if any, as set forth herein; (d) if Executive’s employment is terminated with Good Reason,
thirty (30) days after the Notice of Termination is given, subject to the Company’s right to cure, if any, as set forth herein,
or (e) if Executive’s employment is terminated for any other reason, the date specified in the Notice of Termination (which
shall not be less than fifteen (15) days from the date such Notice of Termination is given).

 

4.4Compensation Upon Termination During
the Employment Period. For purposes of this Agreement, “Accrued Obligations” shall mean: (a) Executive’s
Base Salary earned but not paid prior to the Date of Termination, which shall be paid on the Date of Termination; (b) all benefits
to which Executive is entitled under the terms of the Company’s benefit plans, programs, or arrangements in which she participates,
other than severance plans, programs, or arrangements, as in effect immediately prior to the Date of Termination, payable in accordance
with the terms of such plans, programs, or arrangements; (c) any paid time off earned but not used through the Date of Termination,
which shall be paid on the Date of Termination; and (d) any business expenses and travel expenses that are reimbursable under this
Agreement or otherwise that have been incurred by Executive but unreimbursed by the Date of Termination, subject to the submission
of any required substantiation and documentation as specified pursuant to the Agreement.

 

4.5Termination by the Company with
Cause or by Executive without Good Reason, by Disability, by Reason of Death, or due to Non-Renewal of the Employment Period.
If Executive’s employment hereunder is terminated during the Employment Period (a) by the Company with Cause, (b) by Executive
without Good Reason, (c) by reason of Disability, (d) by reason of Executive’s death, or (e) as a result of
the non-renewal of the Employment Period, then Executive shall be entitled to receive only the Accrued Obligations. For purposes
of this Agreement only, “Cause” shall mean (a) engaging in dishonesty or misconduct that is injurious to the Company;
(b) Executive’s conviction of, or pleas of no lo contendere to, any felony or crime involving moral turpitude, material fraud
or embezzlement of the Company’s property or a charge or indictment of any other felony; or (c) Executive’s breach
of any material terms of this Agreement. “Good Reason” shall mean Executive’s resignation following (a) a material
breach by the Company of its obligations hereunder, provided Executive has first given the Company notice of such alleged breach
and the Company has failed to cure same within thirty (30) days; or (b) a material diminution of Executive’s duties or material
reduction of Executive’s compensation and benefits.

 

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4.6Termination by Company without Cause
or by Executive with Good Reason. If Executive’s employment hereunder is terminated during the Employment Period by the
Company without Cause or by Executive with Good Reason, then Executive will receive the Accrued Obligations and within ten (10)
days following Executive’s execution and delivery of the Release of Claims (defined below), Executive will be entitled to
receive a severance benefit of nine (9) months of Executive’s then-current Base Salary, plus a prorated Target Annual Bonus,
payable either in a lump sum or in installments, as determined by the Company in its sole discretion; provided, however, that if
Executive is terminated by the Company without Cause or if Executive resigns from employment as a result of a material diminution
of Executive’s duties or material reduction of Executive’s compensation and benefits within the twenty four (24) month
period following a Change of Control, the Executive will receive the Accrued Obligations and within ten (10) days following Executive’s
execution and delivery of the Release of Claims (defined below), Executive will be entitled to receive a severance benefit of eighteen
(18) months of Executive’s then-current Base Salary, plus one and one-half times the Executive's pro-rated Target Annual
Bonus, payable either in a lump sum or in installments, as determined by the Company in its sole discretion.

 

4.7No Further Benefits. Except
as otherwise provided in this Agreement, Executive acknowledges that the amounts payable and the benefits provided pursuant to
Section 4 hereof are the exclusive items in the nature of salary, bonus, benefits, and perquisites to which Executive is entitled
in connection with the termination of her employment for any reason.

 

4.8Release. Notwithstanding any
provision herein to the contrary, the payment of any amount or provision of any benefit pursuant to Section 4.6 other than the
Accrued Obligations (collectively, the “Severance Benefits”) shall be conditioned upon Executive’s execution,
delivery to the Company, and non-revocation of a general release of claims against the Company, as well as its current and former
employees, agents, successors and assigns, as well as any company controlled by, controlling, or under common control with the
Company (“Affiliated Company”), prepared by the Company’s outside counsel (“Release of Claims”) within
sixty (60) days following the date of Executive’s Date of Termination. If Executive fails to execute the Release of Claims
in such a timely manner so as to permit any revocation period to expire prior to the end of such sixty (60) day period, or timely
revokes her acceptance of such release following its execution, Executive shall not be entitled to any of the Severance Benefits.
Further, to the extent that any of the Severance Benefits constitutes a Nonqualified Deferred Compensation Plan, as defined below,
any payment of any amount or provision of any benefit otherwise scheduled to occur prior to the sixtieth (60th) day following the
date of Executive’s termination of employment hereunder, but for the condition on executing the Release of Claims as set
forth herein, shall not be made until the sixtieth (60th) day, after which any remaining Severance Benefits shall thereafter be
provided to Executive according to the applicable schedule set forth herein.

 

5.Change of Control.

 

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5.1Upon a Change of Control during the
Employment Period, Executive shall immediately become fully vested, and have a non-forfeitable right to, Executive’s initial
equity-based compensation award, as if all specified performance objectives and other conditions had been fully attained, and Executive
shall have two (2) years following the Change of Control, or the remaining term of the respective options, whichever period is
less, in which to exercise any and all vested options. If Executive is terminated by the Company without Cause or if Executive
resigns from employment as a result of a material diminution of Executive’s duties or material reduction of Executive’s
compensation and benefits within the twenty four (24) month period following a Change of Control, Executive shall immediately become
fully vested, and have a non-forfeitable right to, any previously granted equity-based compensation awards, as if all specified
performance objectives and other conditions had been fully attained, and Executive shall have two (2) years following the Date
of Termination, or the remaining term of the respective options, whichever period is less, in which to exercise any and all vested
options.

 

5.2For purposes of this Agreement, “Change
of Control” shall mean:

 

5.2.1Any individual, entity, or group
(within the meaning of Section 13(d)(3) or 14(d)(2) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”))
(a “Person”), becomes the beneficial owner (within the meaning of Rule 13d-3 promulgated under the Exchange Act) of
35% or more of either (A) the then-outstanding shares of common stock of the Company (the “Outstanding Company Common Stock”)
or (B) the combined voting power of the then-outstanding voting securities of the Company entitled to vote generally in the
election of directors (the “Outstanding Company Voting Securities”); provided, however, that the following acquisitions
shall not constitute a Change of Control: (i) any acquisition directly from the Company, (ii) any acquisition by the Company, (iii)
any acquisition by any employee benefit plan (or related trust) sponsored or maintained by the Company or any Affiliated Company,
or (iv) any acquisition pursuant to a transaction that complies with subclauses (A), (B), and (C) of paragraph 5.2.3 below;

 

5.2.2Individuals who, as of the date
hereof, constitute the Board (the “Incumbent Board”) cease for any reason to constitute at least a majority of the
Board; provided, however, that any individual becoming a director subsequent to the date hereof whose election, or nomination for
election, by the Company’s stockholders was approved by a vote of at least a majority of the directors then comprising the
Incumbent Board shall be considered as though such individual was a member of the Incumbent Board, but excluding, for this purpose,
any such individual whose initial assumption of office occurs as a result of an actual or threatened election contest with respect
to the election or removal of directors or other actual or threatened solicitation of proxies or consents by or on behalf of a
Person other than the Board;

 

5.2.3Consummation of a reorganization,
merger, statutory share exchange, or consolidation or similar transaction involving the Company or any of its subsidiaries, a sale
or other disposition of all or substantially all of the assets of the Company, or the acquisition of assets or securities of another
entity by the Company or any of its subsidiaries (each, a “Business Combination”), in each case unless, following such
Business Combination, (A) all or substantially all of the individuals and entities that were the beneficial owners of the
Outstanding Company Common Stock and the Outstanding Company Voting Securities immediately prior to such Business Combination beneficially
own, directly or indirectly, more than 50% of the then-outstanding shares of common stock (or, for a non-corporate entity, equivalent
securities) and the combined voting power of the then-outstanding voting securities entitled to vote generally in the election
of directors (or, for a non-corporate entity, equivalent governing body), as the case may be, of the entity resulting from such
Business Combination (including, without limitation, an entity that, as a result of such transaction, owns the Company or all or
substantially all of the Company’s assets either directly or through one or more subsidiaries), in substantially the same
proportions as their ownership immediately prior to such Business Combination of the Outstanding Company Common Stock and the Outstanding
Company Voting Securities, as the case may be, (B) no Person (excluding any entity resulting from such Business Combination or
any employee benefit plan (or related trust) of the Company or such entity resulting from such Business Combination) beneficially
owns, directly or indirectly, 35% or more of, respectively, the then-outstanding shares of common stock (or, for a non-corporate
entity, equivalent securities) of the entity resulting from such Business Combination or the combined voting power of the then-outstanding
voting securities of such entity, except to the extent that such ownership existed prior to the Business Combination, and (C) at
least a majority of the members of the board of directors (or, for a non-corporate entity, equivalent governing body) of the entity
resulting from such Business Combination were members of the Incumbent Board at the time of the execution of the initial agreement
or of the action of the Board providing for such Business Combination; or

 

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5.2.4Approval by the stockholders of
the Company of a complete liquidation or dissolution of the Company.

 

6.Section 280G. Notwithstanding
any provision of this Agreement to the contrary, if any payment or benefit Executive would receive pursuant to this Agreement or
otherwise (collectively, the “Payments”) would constitute a “parachute payment” within the meaning of Section
280G of the Internal Revenue Code (the “Code”), and, but for this sentence, would be subject to the excise tax imposed
by Section 4999 of the Code or any similar or successor provision (the “Excise Tax”), then the aggregate amount of
the Payments shall be reduced, but only to the extent necessary so that no portion of the Payments (after reduction) are subject
to the Excise Tax. The professional firm engaged by the Company for general tax purposes as of the day prior to the date of the
event that might reasonably be anticipated to result in Payments that would otherwise be subject to the Excise Tax will perform
the foregoing calculations. If the tax firm so engaged by the Company is serving as accountant or auditor for the acquiring company,
the Company will appoint a nationally recognized tax firm to make the determinations required by this Section. The Company will
bear all expenses with respect to the determinations by such firm required to be made by this Section. The Company and Executive
shall furnish such tax firm such information and documents as the tax firm may reasonably request in order to make its required
determination. The tax firm will provide its calculations, together with detailed supporting documentation, to the Company and
Executive as soon as practicable following its engagement. Any good faith determinations of the tax firm made hereunder will be
final.

 

7.Covenants.

 

7.1Confidential Information. During
the Employment Period and the five (5) year period immediately following the Date of Termination, Executive shall hold all Confidential
Information in strictest confidence and shall not use or disclose such Confidential Information, or cause it to be used or disclosed,
other than as required in performance of Executive’s duties on behalf of the Company or unless first specifically authorized
in writing by Company to Executive. In the event that Executive is required by law to disclose any Confidential Information, Executive
agrees to give the Company prompt advance written notice thereof and to provide the Company with reasonable assistance, at the
Company’s cost and expense, in obtaining an order to protect the Confidential Information from public disclosure. For purposes
of this Agreement, “Confidential Information” shall mean any information about the Company and all of its Affiliated
Companies, including methods of operation, customer lists, products, prices, fees, costs, research and development, inventions,
trade secrets, know-how, software, marketing methods, plans, personnel, suppliers, competitors, markets, and other specialized
information or proprietary matters. “Confidential Information” does not include, and there shall be no obligation hereunder
with respect to, information that (i) is generally available to the public or (ii) becomes generally available to the public other
than as a result of a disclosure not otherwise permissible hereunder.

 

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7.2Noncompetition/Nonsolicitation.
Executive recognizes the benefits derived by her from her employment or engagement by the Company and that the continuation of
such benefits is dependent upon the continued success of the Company which, in turn, is dependent in part upon the preservation
of the Company’s relationships with its clients. Executive believes it to be in her own best interests and in the best interests
of the Company, its stockholders, and its other employees to preserve the Company’s relationships with its clients. In consideration
of the foregoing and of the mutual promises and covenants contained herein, Executive hereby agrees as follows:

 

7.2.1During the Employment Period, Executive
shall use her best efforts to promote the interests of the Company and shall not engage, directly or indirectly, in any business
competitive with the business of the Company, or its subsidiaries, if any.

 

7.2.2During the Employment Period, Executive
shall not, directly or indirectly, on her own behalf or on behalf of any other person or entity, (a) solicit, accept any business
from, or perform any services for any account which is or was a client of the Company; (b) cause or induce or attempt to cause
or induce any client to withdraw any business from the Company; or (c) solicit or accept from any prospective client of the Company
any business or service which was solicited on behalf of the Company by Executive or otherwise misappropriate any business opportunity
of the Company for her own benefit. Executive agrees further not to engage during the one (1) year period following any termination
of employment in any such activities prohibited by this paragraph to the extent that any activity would involve the use of Confidential
Information or trade secrets of the Company.

 

7.2.3During the Employment Period and
for the one (1) year period following any termination thereof, Executive shall not, directly or indirectly, on her own behalf or
on behalf of any other person or entity, cause or induce or attempt to cause or induce any employee of the Company to terminate
her employment with the Company, or advise or recommend to any other person that he employ or solicit for employment any person
who is, or was within the six (6) month period prior to the Date of Termination, an employee or other service provider of the Company,
or its subsidiaries, if any.

 

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7.2.4Notwithstanding any provision contained
herein to the contrary, it is understood that Executive shall have the right and privilege at any time to invest in any competitive
enterprise or business whose capital stock is listed on a national securities exchange in the United States or is traded on the
Nasdaq stock market, provided the total direct and indirect investment of Executive, Executive’s spouse and dependents, represents
not more than two percent (2%) of the total capital stock of such enterprise. Nothing contained herein shall prohibit or restrict
Executive from investing in any non-competitive enterprise or business.

 

7.3Except to the extent materially conflicting
with this Agreement, Executive agrees that she shall abide by, and shall conduct business in accordance with and subject to, all
applicable policies and procedures of the Company, including all employee and ethical policies of the Company, and all client conflict-of-interest
policies applicable to the Company or its subsidiaries generally, as such policies may exist from time to time. Executive also
understands and agrees that the business and affairs of the Company shall be conducted in accordance with the Company’s Corporate
Policies and strict legal and ethical standards, including, without limitation, compliance with all commercial, tax, labor, and
other laws (including the U.S. Foreign Corrupt Practices Act).

 

8.Indemnification. The Company
shall indemnify Executive and hold Executive harmless from any and all claims arising from or related to Executive’s performance
of her duties hereunder to the fullest extent permitted by applicable law and/or the Company’s Directors and Officers Liability
Insurance.

 

9.Tax Withholding; Section 409A.
Any payments or benefits provided for hereunder shall be paid net of any applicable withholding required under federal, state,
or local law and any additional withholding to which Executive has agreed. Notwithstanding any other provision of this Agreement
to the contrary, the following shall apply:

 

9.1In the event that Executive is a “specified
employee” within the meaning of Section 409A of the Code (as determined in accordance with the methodology established by
the Company as in effect on the Date of Termination), any amount or that constitutes a Nonqualified Deferred Compensation Plan
(within the meaning of Section 409A of the Code and Treasury Regulation Section 1.409A-1(a)) that would otherwise be payable or
provided during the six-month period immediately following the Date of Termination shall instead be paid or provided on the first
business day after the date that is six months following Executive’s “separation from service” within the meaning
of Section 409A of the Code.

 

9.2To the extent required by Code Section
409A, any payment or benefits otherwise due to Executive upon her termination of employment with the Company that constitutes a
Nonqualified Deferred Compensation Plan that shall not be made until and unless such termination from employment constitutes a
“separation from service” as such term is defined under Code Section 409A. This provision shall have no effect on payments
or benefits otherwise due or payable to Executive or on her behalf, which are not on account of her termination from employment
with the Company or as a result of her death.

 

10.Notices. For the purpose of
this Agreement, notices and all other communications provided for in this Agreement shall be in writing and shall be deemed to
have been duly given when delivered by hand or sent by reputable international overnight courier, addressed, if to Executive, to
the address inserted below Executive’s signature on the final page hereof and, if to the Company, to the address set forth
below (with required copy), or to such other address as either party may have furnished to the other in writing in accordance herewith,
except that notice of change of address shall be effective only upon actual receipt:

 

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To the Company:

 

Response Genetics, Inc.

1640 Marengo St., 6th Floor

Los Angeles, California 90033

Attention: General Counsel

 

11.Entire Agreement; Modification.
Except as specifically provided herein, this Agreement supersedes any other agreements or representations, oral or otherwise, express
or implied, with respect to the subject matter hereof which have been made by any party; provided, however, that
any equity award agreements or proprietary information agreements previously signed by Executive remain in full force and effect.
This Agreement may only be modified in a writing signed by Executive and a duly authorized officer of the Company.

 

12.Assignment; Successors. This
Agreement will bind and inure to the benefit of and be enforceable by the Company and its respective successors and assigns and
the Executive and the Executive’s heirs, executors, administrators, and successors; provided, however, that the services
provided by the Executive under this Agreement are of a personal nature, and rights and obligations of the Executive under this
Agreement will not be assignable or delegable (except by will or the laws of descent and distribution); provided further, however,
the Company may assign this Agreement to, and all rights hereunder will inure to the benefit of, any subsidiary or affiliate of
the Company or any person, firm or corporation resulting from the reorganization of the Company or succeeding to the business or
assets of the Company by purchase, merger, consolidation or otherwise. This Agreement shall be binding upon and inure to the benefit
of the parties and their respective successors, assigns, heirs and legal representatives

 

13.Applicable
Law. The validity, interpretation and performance of this Agreement shall be governed
by the laws of the State of California, without reference to its conflict-of-law rules. 

 

14.Waiver. No waiver by Executive
or the Company at any time of any breach by the other party hereto of, or of any lack of compliance with, any condition or provision
of this Agreement to be performed by such other party shall be deemed a waiver of similar or dissimilar provisions or conditions
at the same or at any prior or subsequent time.

 

15.Headings. Captions and Section
headings in this Agreement are provided merely for convenience and shall not affect the interpretation of any of the provisions
herein.

 

16.Survival. The obligations
of the Company and Executive under this Agreement which by their nature may require either partial or total performance after the
termination of the Employment Period shall survive such termination.

 

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17.Severability.
In the event any provision of this agreement shall be found unenforceable by a court of competent jurisdiction, the provision shall
be deemed modified to the extent necessary to allow enforceability of the provision as so limited. If a deemed modification is
not satisfactory in the judgment of such court, the unenforceable provision shall be deemed deleted, and the validity and enforceability
of the remaining provisions shall not be affected thereby.

 

18.Counterparts. This Agreement
may be executed in several counterparts, each of which shall be deemed to be an original but all of which together will constitute
one and the same instrument.

 

THE PARTIES TO THIS AGREEMENT HAVE READ THE FOREGOING AGREEMENT
AND FULLY UNDERSTAND EACH AND EVERY PROVISION CONTAINED HEREIN. WHEREFORE, THE PARTIES HAVE EXECUTED THIS AGREEMENT AS OF THE DATE
FIRST ABOVE WRITTEN.

 

	 	RESPONSE GENETICS, INC.

 

 

 

By: /s/ Thomas A. Bologna                     

Name: Thomas A. Bologna

Title: Chairman of the Board of Directors

 

 

 

By: /s/ Stephanie Astrow                          

Stephanie H. Astrow

[Redacted]

 

 

    	10SECOND SUPPLEMENTAL INDENTURE

 

SECOND SUPPLEMENTAL
INDENTURE (this “Supplemental Indenture”), dated as of February 5, 2013, by and among Reach Media, Inc., a Texas
corporation (the “Guaranteeing Subsidiary”), a Subsidiary of Radio One, Inc., a Delaware corporation (the “Issuer”),
the other Guarantors (as defined in the Indenture referred to herein) and Wilmington Trust Company, as trustee under the Indenture
referred to below (the “Trustee”).

 

W I T N E S S E T H

 

WHEREAS, the Issuer
and the Guarantors have heretofore executed and delivered to the Trustee an indenture (as heretofore supplemented and amended,
the “Indenture”), dated as of November 24, 2010 providing for the issuance of 12.5%/15.0% Senior Subordinated
Notes due 2016 (the “Notes”);

 

WHEREAS, the Indenture
provides that under certain circumstances the Guaranteeing Subsidiary shall execute and deliver to the Trustee a supplemental indenture
pursuant to which the Guaranteeing Subsidiary shall unconditionally guarantee all of the Issuer’s Obligations under the Notes
and the Indenture on the terms and conditions set forth herein and under the Indenture (the “Guarantee”); and

 

WHEREAS, pursuant to
Section 9.01 of the Indenture, the Trustee is authorized to execute and deliver this Supplemental Indenture.

 

WHEREAS, all things
necessary to make this Supplemental Indenture a valid indenture and agreement according to its terms have been done.

 

NOW THEREFORE, in consideration
of the foregoing and for other good and valuable consideration, the receipt of which is hereby acknowledged, the parties mutually
covenant and agree for the equal and ratable benefit of the Holders of the Notes as follows:

 

(1)              
Capitalized Terms. Capitalized terms used herein without definition shall have the meanings assigned to them in the
Indenture.

 

(2)              
Agreement to be Bound. The Guaranteeing Subsidiary hereby becomes a party to the Indenture as a Guarantor and as
such will have all of the rights and be subject to all of the obligations and agreements of a Guarantor under the Indenture.

 

(3)              
Guarantee. The Guaranteeing Subsidiary agrees, on a joint and several basis with all the existing Guarantors, to
Guarantee to each Holder of the Notes and the Trustee the Obligations pursuant to Article 11 of the Indenture.

 

(4)              
Governing Law. THIS SUPPLEMENTAL INDENTURE SHALL BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE
STATE OF NEW YORK.

 

(5)              
No Recourse Against Others. No past, present or future director, officer, employee, incorporator, stockholder or
agent of the Guaranteeing Subsidiary, as such, shall have any liability for any obligations of the Issuer or any Guaranteeing Subsidiary
under the Notes, any Guarantees, the Indenture or this Supplemental Indenture or for any claim based on, in respect of, or by reason
of, such obligations or their creation. Each Holder of the Notes by accepting a Note waives and releases all such liability. The
waiver and release are part of the consideration for issuance of the Notes. Such waiver may not be effective to waive liabilities
under the federal securities laws and it is the view of the SEC that such a waiver is against public policy.

 

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(6)              
Counterparts. The parties may sign any number of copies of this Supplemental Indenture. Each signed copy shall be
an original, but all of them together represent the same agreement.

 

(7)              
Effect of the Headings. The Section headings herein are for convenience only and shall not affect the construction
hereof.

 

(8)              
The Trustee. The Trustee shall not be responsible in any manner whatsoever for or in respect of the validity or sufficiency
of this Supplemental Indenture or for or in respect of the recitals contained herein, all of which recitals are made solely by
the Guaranteeing Subsidiary and the Issuer.

 

(9)              
Benefits Acknowledged. The Guaranteeing Subsidiary’s Guarantee is subject to the terms and conditions set forth
in the Indenture. The Guaranteeing Subsidiary acknowledges that it will receive direct and indirect benefits from the financing
arrangements contemplated by the Indenture and this Supplemental Indenture and that the guarantee and waivers made by it pursuant
to this Guarantee are knowingly made in contemplation of such benefits.

 

(10)          
Successors. All agreements of the Guaranteeing Subsidiary in this Supplemental Indenture shall bind its successors,
except as otherwise provided in the Indenture. All agreements of the Trustee in this Supplemental Indenture shall bind its successors.

 

(11)          
Benefits of Supplemental Indenture. Nothing in this Supplemental Indenture or the Notes, express or implied, shall
give to any Person, other than the parties hereto and thereto and their successors hereunder and thereunder and the Holders of
the Notes any benefit of any legal or equitable right, remedy or claim under the Indenture, this Supplemental Indenture or the
Notes.

 

(12)          
Effect of Supplemental Indenture. Upon the execution and delivery of this Supplemental Indenture by the parties hereto,
the Indenture and the Notes shall be amended in accordance herewith, and this Supplemental Indenture shall form a part of the Indenture
for all purposes, and every Holder of Notes heretofore or hereafter authenticated and delivered under the Indenture shall be bound
hereby.

 

(13)          
References to Supplemental Indenture. Any and all notices, requests, certificates and other instruments executed
and delivered after the execution and delivery of this Supplemental Indenture may refer to the Indenture without making specific
reference to this Supplemental Indenture, but nevertheless all such references shall include this Supplemental Indenture unless
the context requires otherwise.

 

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(14)          
Indenture Remains in Full Force and Effect. Except as amended hereby, all provisions in the Indenture shall remain
in full force and effect.

 

(15)          
Indenture and Supplemental Indenture Construed Together. This Supplemental Indenture is an indenture supplemental
to and in implementation of the Indenture, and the Indenture and this Supplemental Indenture shall henceforth be read and construed
together.

 

(16)          
Confirmation and Preservation of Indenture. The Indenture as amended by this Supplemental Indenture is in all respects
confirmed and preserved.

 

(17)          
Trust Indenture Act Controls. If any provision of this Supplemental Indenture limits, qualifies, or conflicts with
another provision which is required to be included in this Supplemental Indenture or the Indenture by the TIA, the required provision
shall control.

 

(18)          
Severability. In case any provision in this Supplemental Indenture shall be invalid, illegal or unenforceable, the
validity, legality and enforceability of the remaining provisions shall not in any way be affected or impaired thereby.

 

 

 

* * * * * *

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IN WITNESS WHEREOF,
the parties hereto have caused this Supplemental Indenture to be duly executed, all as of the date first above written.

 

Dated: February 5, 2013

 

	RADIO ONE, INC.

	 
	 	 
	By:	 
	 	Name:	 
	 	Title:	 
	 	 
	GUARANTORS:	 
	 	 
	BELL BROADCASTING COMPANY	 
	BLUE CHIP BROADCASTING LICENSES, LTD.	 
	BLUE CHIP BROADCASTING, LTD.	 
	CHARLOTTE BROADCASTING, LLC	 
	DISTRIBUTION ONE, LLC	 
	HAWES-SAUNDERS BROADCAST PROPERTIES, INC.	 
	INTERACTIVE ONE, INC.	 
	INTERACTIVE ONE, LLC	 
	NEW MABLETON BROADCASTING CORPORATION	 
	RADIO ONE CABLE HOLDINGS, INC.	 
	RADIO ONE DISTRIBUTION HOLDINGS, LLC	 
	RADIO ONE LICENSES, LLC	 
	RADIO ONE MEDIA HOLDINGS, LLC	 
	RADIO ONE OF ATLANTA, LLC	 
	RADIO ONE OF BOSTON LICENSES, LLC	 
	RADIO ONE OF BOSTON, INC.	 
	RADIO ONE OF CHARLOTTE, LLC	 
	RADIO ONE OF DETROIT, LLC	 
	RADIO ONE OF INDIANA, LLC	 
	RADIO ONE OF INDIANA, L.P.	 
	RADIO ONE OF NORTH CAROLINA, LLC	 
	RADIO ONE OF TEXAS II, LLC	 
	ROA LICENSES, LLC	 
	SATELLITE ONE, L.L.C.	 
	 	 
	 	 
	By:	 
	 	Name:  	 
	 	Title:	 
	 	 
	 	 
	REACH MEDIA, INC.	 
	 	 
	By:	 
	 	Name:	 
	 	Title:	 
	 	 	 	 

 

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	 	WILMINGTON TRUST COMPANY,
 as Trustee
	 	 
	 	 
	 	By: 	 
	 	 	Name:
	 
	 	 	Title:	 

 

 

  

 

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