Document:

Netscout Systems, Inc. 2007 Equity Incentive Plan

 Exhibit 10.1 
 NETSCOUT SYSTEMS, INC. 
 2007 EQUITY INCENTIVE PLAN

 1    Purpose and Eligibility 
 The purpose of this 2007 Equity Incentive Plan (the “Plan”) of NetScout Systems, Inc. (the “Company”) is to provide restricted stock units, stock, stock options, and other equity interests in the Company (each an
“Award”) to employees, officers, directors, consultants and advisors of the Company and its Subsidiaries, all of whom are eligible to receive Awards under the Plan. Any person to whom an Award has been granted under the Plan is called a
“Participant”. Additional definitions are contained in Section 9. 
 2     Administration 
 2.1 Administration by Board of Directors. The Plan will be administered by the Board of Directors of the Company (the “Board”). The
Board, in its sole discretion, shall have the authority to grant and amend Awards, to adopt, amend and repeal rules relating to the Plan and to interpret and correct the provisions of the Plan and any Award. All decisions by the Board shall be final
and binding on all interested persons. Neither the Company nor any member of the Board shall be liable for any action or determination relating to the Plan. 
 2.2 Appointment of Committees. To the extent permitted by applicable law, the Board may delegate any or all of its powers under the Plan to one or more committees or subcommittees of the Board
(a “Committee”). All references in the Plan to the “Board” shall mean such Committee or the Board. 
 2.3
Delegation to Executive Officers. To the extent permitted by applicable law, the Board may delegate to one or more executive officers of the Company the power to grant Awards and exercise such other powers under the Plan as the Board may
determine, provided that the Board shall fix the maximum number of Awards to be granted and the maximum number of shares issuable to any one Participant pursuant to Awards granted by such executive officers. 
 3     Stock Available for Awards 
 3.1
Type of Security; Number of Shares. Subject to adjustment under Section 3.3, the aggregate number of shares of common stock of the Company (the “Common Stock”) that may be issued pursuant to the Plan is 5,000,000 shares. If any
Award expires, or is terminated, surrendered or forfeited, in whole or in part, the unissued Common Stock covered by such Award shall again be available for the grant of Awards under the Plan. If shares of Common Stock issued pursuant to the Plan
are repurchased by, or are surrendered or forfeited to, the Company at no more than cost, such shares of Common Stock shall again be available for the grant of Awards under the Plan; provided, however, that the cumulative number of such
shares that may be so reissued under the Plan will not exceed 5,000,000 shares. Shares issued under the Plan may consist in whole or in part of authorized but unissued shares or treasury shares. 
 3.2 Per-Participant Limit. Subject to adjustment under Section 3.3, no Participant may be granted Awards during any one fiscal year with
respect to more than 500,000 shares of Common Stock. 
 3.3 Adjustment to Common Stock. In the event of any stock split, stock
dividend, recapitalization, reorganization, merger, consolidation, combination, exchange of shares, liquidation, spin-off, split-up, or other similar change in capitalization or event (an “Extraordinary Capitalization Event”), (i) the
number and class of securities available for Awards under the Plan and the per-Participant share limit, (ii) the number and class of securities, vesting schedule and exercise price per share subject to each outstanding Option, (iii) the
repurchase price per security subject to repurchase, and (iv) the terms of each other outstanding stock-based Award shall be adjusted (or substituted Awards may be made) by the Board in a proportionate and equitable manner to the extent that
such Extraordinary Capitalization Event increases or decreases the actual outstanding shares of Common Stock of the Company as of immediately prior to such Extraordinary Capitalization Event. 

 4     Stock Options 
 4.1 General. The Board may grant options to purchase Common Stock (each, an “Option”) and determine the number of shares of Common Stock to be covered by each Option, the exercise price of each Option
and the conditions and limitations applicable to the exercise of each Option and the Common Stock issued upon the exercise of each Option, including vesting provisions, repurchase provisions and restrictions relating to applicable federal or state
securities laws, as it considers advisable. 
 4.2 Incentive Stock Options. An Option that the Board intends to be an “incentive
stock option” as defined in Section 422 of the Code (an “Incentive Stock Option”) shall be granted only to employees of the Company or a Subsidiary and shall be subject to and shall be construed consistently with the requirements
of Section 422 of the Code. The Board and the Company shall have no liability if an Option or any part thereof that is intended to be an Incentive Stock Option does not qualify as such. An Option or any part thereof that does not qualify as an
Incentive Stock Option is referred to herein as a “Nonqualified Stock Option”. 
 4.3 Exercise Price. The Board shall
establish the exercise price (or determine the method by which the exercise price shall be determined) at the time each Option is granted and specify it in the applicable option agreement; provided that the exercise price shall not be less than the
fair market value of the Company’s Common Stock on the date of grant. The exercise price with respect to an Incentive Stock Option granted to an employee who at the time of grant owns (directly or under the attribution rules of
Section 424(d) of the Code) stock representing more than 10% of the voting power of all classes of stock of the Company or of any Subsidiary shall be at least 110% of the fair market value of the Company’s Common Stock on the date of
grant. 
 4.4 Duration of Options. Each Option shall be exercisable at such times and subject to such terms and conditions as the
Board may specify in the applicable option agreement; provided that no Incentive Stock Option shall expire later than 10 years from its date of grant, and no Incentive Stock Option granted to an employee who owns (directly or under the attribution
rules of Section 424(d) of the Code) stock possessing more than 10% of the total combined voting power of all classes of stock of the Company or any Subsidiary shall expire later than 5 years from its date of grant. 
 4.5 Exercise of Option. Options may be exercised only by delivery to the Company of a written notice of exercise signed by the proper person
together with payment in full as specified in Section 4.6 for the number of shares for which the Option is exercised. 
 4.6 Payment
Upon Exercise. Common Stock purchased upon the exercise of an Option shall be paid for by one or any combination of the following forms of payment: 
 4.6.1 by check payable to the order of the Company; 
 4.6.2 except as otherwise explicitly
provided in the applicable option agreement, and only if the Common Stock is then publicly traded, delivery of an irrevocable and unconditional undertaking by a creditworthy broker to deliver promptly to the Company sufficient funds to pay the
exercise price, or delivery by the Participant to the Company of a copy of irrevocable and unconditional instructions to a creditworthy broker to deliver promptly to the Company cash or a check sufficient to pay the exercise price; or 
 4.6.3 to the extent explicitly provided in the applicable option agreement and not otherwise prohibited by applicable law, by
(x) delivery of shares of Common Stock owned by the Participant valued at fair market value (as determined by the Board or as determined pursuant to the applicable option agreement), (y) delivery of a promissory note of the Participant to
the Company (and delivery to the Company by the Participant of a check in an amount equal to the par value of the shares purchased), or (z) payment of such other lawful consideration as the Board may determine. 

 4.7 No Repricing. Other than in connection with a change in the Company’s capitalization (as
described in Section 3.3), without stockholder approval (i) the exercise price of an Option may not be reduced, and (ii) no Option may be amended or cancelled for the purpose of repricing, replacing or regranting such Option with an
exercise price that is less than the original exercise price of such Option. 
 5     Restricted Stock 
 5.1 Grants. The Board may grant Awards entitling recipients to acquire shares of Common Stock, subject to (i) delivery to the Company by the
Participant of a check in an amount at least equal to the par value of the shares purchased, and (ii) the right of the Company to repurchase all or part of such shares at their issue price or other stated or formula price from the Participant
in the event that conditions specified by the Board in the applicable Award are not satisfied prior to the end of the applicable restriction period or periods established by the Board for such Award (each, a “Restricted Stock Award”).

 5.2 Terms and Conditions. The Board shall determine the terms and conditions (or provide for no conditions) of any such Restricted
Stock Award. Any stock certificates issued in respect of a Restricted Stock Award shall be registered in the name of the Participant and, unless otherwise determined by the Board, deposited by the Participant, together with a stock power endorsed in
blank, with the Company (or its designee). After the expiration of the applicable restriction periods, the Company (or such designee) shall deliver the certificates no longer subject to such restrictions to the Participant or, if the Participant has
died, to the beneficiary designated by a Participant, in a manner determined by the Board, to receive amounts due or exercise rights of the Participant in the event of the Participant’s death (the “Designated Beneficiary”). In the
absence of an effective designation by a Participant, Designated Beneficiary shall mean the Participant’s estate. 
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    Restricted Stock Units 
 The Board may grant Awards entitling recipients to receive shares of Common Stock (each, a
“Restricted Stock Unit Award”), subject to any terms and conditions established for such Awards. The Board shall determine the terms and conditions (or provide for no conditions) of any such Restricted Stock Unit Award and such terms and
conditions will be reflected in the applicable Restricted Stock Unit Award agreement. 
 7     Other Stock-Based Awards 
 The Board shall have the right to grant other Awards based upon the Common Stock having such terms and conditions as the Board may determine, including,
without limitation, the grant of shares based upon certain conditions, the grant of securities convertible into Common Stock and the grant of stock appreciation rights, phantom stock awards, or other stock units. 
 8     General Provisions Applicable to Awards 
 8.1 Transferability of Awards. 
 8.1.1 Except as the Board may otherwise determine or provide in an Award, Awards
shall not be sold, assigned, transferred, pledged or otherwise encumbered by the person to whom they are granted, either voluntarily or by operation of law, except by will or the laws of descent and distribution, and, except as set forth in
Section 8.1.2 below, during the life of the Participant, shall be exercisable only by the Participant. References to a Participant, to the extent relevant in the context, shall include references to authorized transferees. 
 8.1.2 During the life of the Participant, an Option shall be exercisable only by him, by a conservator or guardian duly appointed for him
by reason of his incapacity or by the person appointed by the Participant in a durable power of attorney acceptable to the Company’s counsel. Notwithstanding anything to the contrary in this Section 8.1, the Board may in its discretion
permit a Participant who has received a Nonqualified 

 
Stock Option to transfer the Nonqualified Stock Option to a member of the Immediate Family (as hereinafter defined) of the Participant, to a trust solely for
the benefit of the Participant and the Participant’s Immediate Family or to a partnership or limited liability company whose only partners or members are the Participant and members of the Participant’s Immediate Family. “Immediate
Family” shall mean, with respect to any Participant, the Participant’s child, stepchild, grandchild, parent, stepparent, grandparent, spouse, sibling, mother-in-law, father-in-law, son-in-law, daughter-in-law, brother-in-law or
sister-in-law, and shall include adoptive relationships. 
 8.2 Documentation. Each Award under the Plan (other than a grant of stock
with no restrictions) shall be evidenced by a written instrument in such form as the Board shall determine or as executed by an officer of the Company pursuant to authority delegated by the Board. Each Award may contain terms and conditions in
addition to those set forth in the Plan provided that such terms and conditions do not contravene the provisions of the Plan. 
 8.3
Board Discretion. The terms of each type of Award need not be identical, and the Board need not treat Participants uniformly. 
 8.4
Termination of Status. The Board shall determine the effect on an Award of the disability, death, retirement, authorized leave of absence or other change in the employment or other status of a Participant and the extent to which, and the
period during which, the Participant, or the Participant’s legal representative, conservator, guardian or Designated Beneficiary, may exercise rights under the Award. 
 8.5    Acquisition of the Company. 
 8.5.1 Consequences of an Acquisition. 
 8.5.1.A Unless otherwise expressly provided in the applicable Option or Award, upon the occurrence of an Acquisition, the Board or the
board of directors of the surviving or acquiring entity (as used in this Section 8.5.1.A, also the “Board”) shall, as to outstanding Awards (on the same basis or on different bases, as the Board shall specify), make appropriate
provision for the continuation of such Awards by the Company or the assumption of such Awards by the surviving or acquiring entity and by substituting on an equitable basis for the shares then subject to such Awards either (a) the consideration
payable with respect to the outstanding shares of Common Stock in connection with the Acquisition, (b) shares of stock of the surviving or acquiring corporation or (c) such other securities as the Board deems appropriate, the fair market
value of which (as determined by the Board in its sole discretion) shall not materially differ from the fair market value of the shares of Common Stock subject to such Awards immediately preceding the Acquisition. In addition to or in lieu of the
foregoing, with respect to outstanding Options, the Board may, upon written notice to the affected optionees, provide that one or more Options must be exercised, to the extent then exercisable or to become exercisable as a result of the Acquisition,
within a specified number of days of the date of such notice, at the end of which period such Options shall terminate; or terminate one or more Options in exchange for a cash payment equal to the excess of the fair market value (as determined by the
Board in its sole discretion) of the shares subject to such Options (to the extent then exercisable or to become exercisable as a result of the Acquisition) over the exercise price thereof. 
 8.5.1.B An “Acquisition” shall mean: (x) any merger or consolidation after which the voting securities of the Company
outstanding immediately prior thereto represent (either by remaining outstanding or by being converted into voting securities of the surviving or acquiring entity) less than 50% of the combined voting power of the voting securities of the Company or
such surviving or acquiring entity outstanding immediately after such event; or (y) any sale of all or substantially all of the assets or capital stock of the Company (other than in a spin-off or similar transaction) or (z) any other
acquisition of the business of the Company, as determined by the Board. 

 8.5.2 Assumption of Options Upon Certain Events. In connection with a merger or
consolidation of an entity with the Company or the acquisition by the Company of property or stock of an entity, the Board may grant Awards under the Plan in substitution for stock and stock-based awards issued by such entity or an affiliate
thereof. The substitute Awards shall be granted on such terms and conditions as the Board considers appropriate in the circumstances. 
 8.6
Withholding. Each Participant shall pay to the Company or an employing Subsidiary, or make provisions satisfactory to the Company or an employing Subsidiary for payment of, any taxes required by law to be withheld in connection with Awards to
such Participant no later than the date of the event creating the tax liability. The Board may allow Participants to satisfy such tax obligations in whole or in part by transferring shares of Common Stock, including shares retained from the Award
creating the tax obligation, valued at their fair market value (as determined by the Board or as determined pursuant to the applicable option agreement) to the extent permitted by law; provided, however, that payment of withholding obligation in the
form of shares shall not be made with respect to an amount in excess of the minimum required withholding. The Company or an employing Subsidiary may, to the extent permitted by law, deduct any such tax obligations from any payment of any kind
otherwise due to a Participant. 
 8.7 Amendment of Awards. The Board may amend, modify or terminate any outstanding Award including,
but not limited to, substituting therefor another Award of the same or a different type, changing the date of exercise or realization, and converting an Incentive Stock Option to a Nonqualified Stock Option; provided that the Participant’s
consent to such action shall be required unless the Board determines that the action, taking into account any related action, would not materially and adversely affect the Participant. 
 8.8 Conditions on Delivery of Stock. The Company will not be obligated to deliver any shares of Common Stock pursuant to the Plan or to remove
restrictions from shares previously delivered under the Plan until (i) all conditions of the Award have been met or removed to the satisfaction of the Company, (ii) in the opinion of the Company’s counsel, all other legal matters in
connection with the issuance and delivery of such shares have been satisfied, including any applicable securities laws and any applicable stock exchange or stock market rules and regulations, and (iii) the Participant has executed and delivered
to the Company such representations or agreements as the Company may consider appropriate to satisfy the requirements of any applicable laws, rules or regulations. 
 8.9 Acceleration. The Board may at any time provide that any Options shall become immediately exercisable in full or in part, that any Restricted Stock Awards shall be free of some or all restrictions, or that
any other stock-based Awards may become exercisable in full or in part or free of some or all restrictions or conditions, or otherwise realizable in full or in part, as the case may be, despite the fact that the foregoing actions may (i) cause
the application of Sections 280G and 4999 of the Code if a change in control of the Company occurs, or (ii) disqualify all or part of the Option as an Incentive Stock Option. 
 8.10 Awards to Non-United States Persons. Awards may be made to Participants who are foreign nationals or employed outside the United States on
such terms and conditions different from those specified in the Plan as the Board considers necessary or advisable to achieve the purposes of the Plan or to comply with applicable laws. The Board shall have the right to amend the Plan, consistent
with its authority to amend the Plan as set forth in Section 9.5, to obtain favorable tax treatment for such Participants, and any such amendments shall be evidenced by an Appendix to the Plan. The Board may delegate this authority to a
Committee thereof. 
 9     Miscellaneous 
 9.1 Definitions. 
 9.1.1 “Company,” for purposes of eligibility under the Plan,
shall include any present or future subsidiary corporations of NetScout Systems, Inc., as defined in Section 424(f) of the Code (a “Subsidiary”), and any present or future parent corporation of NetScout Systems, Inc., as defined in

 
Section 424(e) of the Code. For purposes of Awards other than Incentive Stock Options, the term “Subsidiary” shall include any other business
venture in which the Company has a direct or indirect significant interest, as determined by the Board in its sole discretion. 
 9.1.2 “Code” means the Internal Revenue Code of 1986, as amended, and any regulations promulgated thereunder. 
 9.1.3 “employee” for purposes of eligibility under the Plan shall include a person to whom an offer of employment has been extended by the Company. 
 9.1.4 “Exchange Act” means the Exchange Act of 1934, as amended. 
 9.2 No Right To Employment or Other Status. No person shall have any claim or right to be granted an Award, and the grant of an Award shall not be
construed as giving a Participant the right to continued employment or any other relationship with the Company. The Company expressly reserves the right at any time to dismiss or otherwise terminate its relationship with a Participant free from any
liability or claim under the Plan. 
 9.3 No Rights As Stockholder. Subject to the provisions of the applicable Award, no Participant
or Designated Beneficiary shall have any rights as a stockholder with respect to any shares of Common Stock to be distributed with respect to an Award until becoming the record holder thereof. 
 9.4 Effective Date and Term of Plan. The Plan shall become effective on the date on which it is adopted by the stockholders of the Company. No
Awards shall be granted under the Plan after the completion of ten years from the date on which the Plan was adopted by the stockholders of the Company, but Awards previously granted may extend beyond that date. 
 9.5 Amendment of Plan. The Board may amend, suspend or terminate the Plan or any portion thereof at any time; provided, however, that without
approval of the Company’s stockholders there shall be no: (i) increase in the total number of shares covered by the Plan, except by operation of the provisions of Section 3.3, or the aggregate number of shares of Common Stock that may
be issued to any single person in a period; (ii) change in the class of persons eligible to receive Awards under the Plan; or (iii) other change in the Plan that requires stockholder approval under applicable law or stock exchange rules.

 9.6 Section 409A of the Internal Revenue Code. The Awards granted pursuant to the Plan are intended to avoid the potential
adverse tax consequences to Participants of Section 409A of the Code, and the Board may in its sole discretion make such modifications to any Award agreement pursuant to the Plan as it deems necessary or advisable to avoid such adverse tax
consequences. 
 9.7 Governing Law. The provisions of the Plan and all Awards made hereunder shall be governed by and interpreted in
accordance with the laws of Delaware, without regard to any applicable conflicts of law. 
 9.8 Use of Proceeds. The proceeds from the
sale of Common Stock pursuant to Awards shall constitute general funds of the Company. 
 9.9 Section 16 Matters. With respect to
persons subject to Section 16 of the Exchange Act (“Insiders”), transactions under the Plan are intended to comply with all applicable conditions of Rule 16b-3 or its successor under the Exchange Act. To the extent any provision of
the Plan or action by the Board, or any Committee thereof, fails to so comply, it shall be deemed to be modified so as to be in compliance with such Rule or, if such modification is not possible, it shall be deemed to be null and void, to the extent
permitted by law and deemed advisable by the Board.Consulting Agreement,

 Exhibit 10.39 
 CONSULTING AGREEMENT 
 THIS CONSULTING
AGREEMENT (the “Agreement”) is made and entered into by and between KOSAN BIOSCIENCES INCORPORATED, a Delaware corporation having an address at 3832 Bay
Center Place, Hayward, CA 94545 (the “Company”), and MARGARET A. HORN, an individual, having an address at _________________, (“Consultant”), effective as set forth in
Section 8.3 herein. 
 RECITALS 
 WHEREAS, Consultant previously served as the Company’s Senior Vice President, Legal and Corporate Development and General Counsel and has resigned her employment effective
August 24, 2007; 
 WHEREAS, given her prior service to the Company, Consultant has skills and
knowledge in the Company’s field of endeavor and thus is well suited to advise the Company; and 
 WHEREAS, the Company desires that Consultant advise and consult with the Company in Consultant’s area of expertise and on the terms and conditions set forth herein. 
 NOW THEREFORE, in consideration of the mutual obligations specified in this Agreement, the parties
agree to the following: 
 1. CONSULTING SERVICES. Consultant shall provide consulting
services to the Company, the specific nature and amount of which shall be as described generally in Exhibit A and in accordance with the Company’s more specific instructions. Exhibit A lists Consultant’s main contact person for the
Services, and this person will be the primary source of Company’s more specific instructions regarding the Services. The Company may change Consultant’s main contact upon written notice. Consultant will perform the Services in strict
accordance with Exhibit A and the Company’s other directions, using Consultant’s highest degree of professional skill and expertise. 
 Consultant shall render the Services at such times and in such quantities as are set forth in Exhibit A. Consultant shall perform the Services at the Company’s principal place of business, another Company location, or at other places
set forth in Exhibit A. 
 2. COMPENSATION. Company shall compensate Consultant in accordance with
Exhibit A for Services actually provided by Consultant in accordance with this Agreement. 
 3. AMENDMENTS
TO EXHIBIT A. Exhibit A sets forth the specifics of the Services, the location of the Services and compensation for the Services as of the Effective Date. Exhibit A may only be amended by a writing signed by an
authorized representative of each party (in the case of the Company, a person having a seniority level of Senior Vice President or higher). 
  

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 4. INDEPENDENT CONTRACTOR STATUS. It
is understood and agreed that Consultant is an independent contractor, is not an agent or employee of the Company, and is not authorized to act on behalf of the Company. Consultant agrees not to hold Consultant out as, or give any person any reason
to believe that Consultant is an employee, agent, joint venturer or partner of the Company. Consultant will not be eligible for any employee benefits, nor will the Company make deductions from any amounts payable to Consultant for taxes or insurance
(except to the extent the Company is required by law to do so). All payroll and employment taxes, insurance, and benefits shall be the sole responsibility of Consultant. Consultant retains the right to provide services for others during the term of
this Agreement and is not required to devote Consultant’s services exclusively for the Company, provided that, during the term of this Agreement, Consultant may not provide services (as a consultant, employee, or in any other status) to a
competing entity of the Company, or engage in activities that compete with the Company or that otherwise conflict with his duties to the Company hereunder. 
 5. NO SOLICITATION. During the term of this Agreement and for one (1) year after its termination, Consultant will not personally or through others recruit,
solicit or induce, or attempt to recruit, solicit or induce, any employee or independent contractor of the Company to terminate his or her employment or contractor relationship, as applicable, with the Company. 
 6. CONFIDENTIAL INFORMATION. 
 6.1 Company Information. During the term of this Agreement and in the course of Consultant’s performance hereunder, Consultant may receive or
otherwise be exposed to confidential or proprietary information relating to the Company’s technology know-how, data, inventions, developments, plans, business practices or strategies. Such confidential or proprietary information of the Company
(collectively referred to as “Information”) may include but not be limited to: (i) confidential or proprietary information supplied to Consultant with the legend “Confidential” or equivalent; (ii) the Company’s
marketing and customer support strategies, financial information (including sales, costs, profits and pricing methods), internal organization, employee information, and customer lists; (iii) the Company’s technology, including, but not
limited to, discoveries, inventions, research and development efforts, data, software, trade secrets, processes, samples, media and/or cell lines (and procedures and formulations for producing any such samples, media and/or cell lines), vectors,
viruses, assays, plasmids, formulas, methods, product and know-how and show-how; (iv) all derivatives, improvements, additions, modifications, and enhancements to any of the above, including any such information or material created or developed
by Consultant under this Agreement; or (v) information of third parties as to which the Company has an obligation of confidentiality. Consultant agrees that any Information provided to Consultant prior to the Effective Date shall be considered
“Information” and protected hereunder. 
 Consultant acknowledges the confidential and secret character of the Information and
agrees that the Information (with the exception of information in category (v)) is the sole, exclusive and extremely valuable property of the Company. Accordingly, Consultant shall not reproduce any of the Information without the applicable prior
written consent of the Company, use the Information except in the performance of this Agreement, nor disclose all or any part of the Information in any form to any third party, either during or after the term of this Agreement. Upon termination of
this Agreement for any reason, including expiration of term, Consultant agrees to cease using and to return to the Company all whole and partial copies of the Information. 
  

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 Consultant shall not remove from the premises of Company or otherwise transfer to any third party any
materials to which Company provides Consultant access, unless Consultant has express advance written consent from Company. 
 6.2
Other Employer Information. Consultant agrees that Consultant will not, during Consultant’s engagement with the Company, improperly use or disclose any proprietary information or trade secrets of Consultant’s former or concurrent
employers or companies with which Consultant has or has had a consulting or other relationship, if any, and that Consultant will not bring onto the premises of the Company any unpublished documents or any property belonging to Consultant’s
former or concurrent employers or companies unless consented to in writing by said employers or companies. 
 6.3 Third Party
Information. Consultant recognizes that the Company has received and in the future will receive from third parties their confidential or proprietary information subject to a duty on the Company’s part to maintain the confidentiality of such
information and, in some cases, to use it only for certain limited purposes. Consultant agrees that Consultant owes the Company and such third parties, both during the term of Consultant’s engagement and thereafter, a duty to hold all such
confidential or proprietary information in the strictest confidence and not to disclose it to any person, firm or corporation (except in a manner that is consistent with the Company’s agreement with the third party) or use it for the benefit of
anyone other than the Company or such third party (consistent with the Company’s agreement with the third party). 
 7.
INVENTIONS. 
 7.1 Disclosure of Inventions. Consultant shall promptly and fully disclose
to the Company any and all ideas, improvements, inventions, know-how, techniques and works of authorship learned, conceived or developed by Consultant pursuant to Consultant’s performance of the Services for the Company or pursuant to any
services provided to the Company prior to the Effective Date (together with all intellectual property rights therein (including without limitation patent applications and patents), the “Consulting Inventions”). Consultant shall keep and
maintain adequate and current records (in the form of notes, sketches, drawings or in any other form that may be required by the Company) of all work performed relating to the Services, including all proprietary information developed relating
thereto. Such records shall be available to and remain the sole property of the Company at all times. 
 7.2 Inventions Assigned to
the Company. Consultant agrees that any and all Consulting Inventions shall be the sole and exclusive property of the Company. Accordingly, Consultant hereby assigns to the Company all Consultant’s right, title and interest in and to the
Consulting Inventions, and agrees to execute and deliver all documents and take all reasonable, lawful actions to assist the Company to evidence or record such assignment or perfect or enforce the Consulting Inventions. Further, if Company is
unable, after making reasonable inquiry, to obtain Consultant’s signature on any such documents, Consultant hereby appoints Company as Consultant’s attorney-in-fact to execute and deliver such documents. 
  

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 7.3 Proprietary Information and Inventions of Concurrent Employers. The Company acknowledges
that Consultant may be concurrently employed by others during the course of this Agreement. The Company shall have no rights to the proprietary information or inventions developed by Consultant during the course of
his employment with such concurrent employers. 
 8. RELEASE OF
CLAIMS. In exchange for the compensation and benefits to be provided to Consultant by the Company pursuant to this Agreement (including the continued vesting of Consultant’s Stock Options as set forth in
Exhibit A), Consultant hereby provides the following Release: 
 8.1 General Release. Consultant hereby generally and
completely releases the Company and its directors, officers, employees, shareholders, partners, agents, attorneys, predecessors, successors, parent and subsidiary entities, insurers, affiliates, and assigns (collectively, the “Released
Parties”) from any and all claims, liabilities and obligations, both known and unknown, arising out of or in any way related to events, acts, conduct, or omissions occurring at any time prior to or on the date that Consultant signs this
Agreement (collectively, the “Released Claims”). The Released Claims include, but are not limited to: (1) all claims arising out of or in any way related to Consultant’s employment with the Company or the termination of that
employment; (2) all claims related to Consultant’s compensation or benefits, including salary, bonuses, relocation benefits, housing assistance, commissions, vacation pay, expense reimbursements, severance pay, fringe benefits, stock,
stock options, or any other ownership or equity interests; (3) all claims for breach of contract, wrongful termination, and breach of the implied covenant of good faith and fair dealing; (4) all tort claims, including claims for fraud,
defamation, emotional distress, and discharge in violation of public policy; and (5) all federal, state, and local statutory claims, including claims for discrimination, harassment, retaliation, attorneys’ fees, or other claims arising
under the federal Civil Rights Act of 1964 (as amended), the federal Americans with Disabilities Act of 1990, the federal Age Discrimination in Employment Act (as amended) (“ADEA”), the federal Family and Medical Leave Act, the California
Labor Code (as amended), the California Family Rights Act, and the California Fair Employment and Housing Act (as amended). 
 8.2
Excluded Claims. Notwithstanding the foregoing, the following are not included in the Released Claims (the “Excluded Claims”): (i) any rights or claims for indemnification Consultant may have pursuant to any written
indemnification agreement to which she is a party, the charter, bylaws, or operating agreements of any of the Released Parties, or under applicable law; or (ii) any rights which are not waivable as a matter of law. In addition, Consultant
understands that nothing in this Release prevents her from filing, cooperating with, or participating in any proceeding before the Equal Employment Opportunity Commission, the Department of Labor, or the California Department of Fair Employment and
Housing, except that Consultant acknowledges and agrees that she shall not recover any monetary benefits in connection with any such claim, charge or proceeding with regard to any claim released herein. Consultant hereby represents and warrants
that, other than the Excluded Claims, she is not aware of any claims she has or might have against any of the Released Parties that are not included in the Released Claims. 
  

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 8.3 ADEA Waiver. Consultant acknowledges that she is knowingly and voluntarily waiving and
releasing any rights she may have under the ADEA, and that the consideration given for the waiver and release in the preceding paragraphs is in addition to anything of value to which she is already entitled. Consultant further acknowledges that she
has been advised by this writing that: (1) her waiver and release do not apply to any rights or claims that may arise after the date she signs this Agreement; (2) she should consult with an attorney prior to signing this Agreement
(although she may choose voluntarily not to do so); (3) she has twenty-one (21) days to consider this release (although she may choose voluntarily to sign this Agreement earlier); (4) she has seven (7) days following the date she
signs this Agreement to revoke this ADEA waiver by providing written notice of revocation to the Company’s Chief Executive Officer; and (5) this Agreement will not be effective until the date upon which the revocation period has expired,
which will be the eighth calendar day after the date she signs it provided that she does not revoke the ADEA Waiver contained in this Section 8.3 (the “Effective Date”). 
 8.4 Section 1542 Waiver. CONSULTANT UNDERSTANDS THAT THIS RELEASE AGREEMENT INCLUDES A RELEASE OF ALL KNOWN AND UNKNOWN CLAIMS.
Consultant acknowledges that she has read and understands Section 1542 of the California Civil Code which reads as follows: “A general release does not extend to claims which the creditor does not know or suspect to exist in his or her
favor at the time of executing the release, which if known by him or her must have materially affected his or her settlement with the debtor.” Consultant hereby expressly waives and relinquishes all rights and benefits under that section
and any law or legal principle of similar effect in any jurisdiction with respect to her release of claims herein, including but not limited to my release of unknown and unsuspected claims. 
 8.5 Representations. Consultant hereby represents and warrants that: (1) she has been paid all compensation owed and for all hours
worked; (2) she has not earned and is not owed any bonus or incentive compensation; (3) she is not owed any relocation benefits; (4) she has received all the leave and leave benefits and protections for which she is eligible, pursuant
to the Family and Medical Leave Act, the California Family Rights Act, or otherwise; and (5) she has not suffered any on-the-job injury for which she has not already filed a workers’ compensation claim. 
 8.6 Covenants. Consultant further agrees: (1) not to disparage any of the Released Parties in any manner likely to be harmful to its
or their business, business reputations, or personal reputations (although she may respond accurately and fully to any question, inquiry or request for information as required by legal process); (2) not to voluntarily (except in response to
legal compulsion) assist any third party in bringing or pursuing any proposed or pending litigation, arbitration, administrative claim or other formal proceeding against any of the Released Parties; and (3) to reasonably cooperate with the
Company by voluntarily (without legal compulsion) providing accurate and complete information, in connection with either or both parties’ actual or contemplated defense, prosecution, or investigation of any claims or demands by or against third
parties, or other matters, arising from events, acts, or failures to act that occurred during the period of Consultant’s employment. 
  

 5 

 9. TERMINATION. Either party may terminate this Agreement at any time by
giving the other party thirty (30) days written notice. Either party may terminate this Agreement upon written notice in the case of material breach of the terms of this Agreement by the other party, if such breach remains uncured thirty
(30) days after written notice of such breach is sent by the terminating party. In the event of any termination, Consultant shall cease work immediately, unless otherwise advised by the Company, shall return to the Company all Information,
Consulting Inventions, and other materials belonging to the Company, and shall notify the Company of costs incurred up to the termination date. Sections 5, 6, 7, 8, 10, 11 and 12 of this Agreement shall survive any termination of this Agreement. In
the event that the Agreement is not terminated earlier as provided herein, it shall expire by its terms, and terminate, on January 3, 2008 unless the parties agree in writing to extend the term of the Agreement. 
 10. COMPLIANCE WITH APPLICABLE LAWS. Consultant warrants that
all material supplied and work performed under this Agreement complies with or will comply with all applicable United States and foreign laws and regulations. 
 11. Assignment; Benefit. This Agreement is for the personal services of Consultant and may not be assigned by Consultant. Consultant may not delegate any of Consultant’s duties under this Agreement
nor shall it be assignable by Consultant by operation of law, without the prior written consent of the Company. This Agreement may be assigned at any time by the Company in its discretion, provided that Consultant would not be required to
perform personal services for any entity other than an entity (a) affiliated with the Company or (b) that has merged with or acquired all or substantially all of the Company’s assets to which the Services relate. The parties’
rights and obligations under this Agreement will bind and inure to the benefit of their respective successors, heirs, executors, and administrators and permitted assigns. 
 12. LEGAL AND EQUITABLE REMEDIES. Consultant hereby acknowledges and agrees that if Consultant breaches this Agreement, including, without
limitation, by the actual or threatened disclosure of Information or Consulting Inventions without the prior express written consent of the Company, the Company will suffer an irreparable injury, such that no remedy at law will afford it adequate
protection against, or appropriate compensation for, such injury. Accordingly, Consultant hereby agrees that the Company shall be entitled to specific performance of Consultant’s obligations under this Agreement, as well as such further relief
as may be granted by a court of competent jurisdiction. 
 13. GOVERNING LAW;
SEVERABILITY. This Agreement shall be governed by and construed according to the laws of California, without giving effect to its conflict of laws rules. If any provision of this Agreement is found by a court of competent
jurisdiction to be unenforceable, that provision shall be severed and the remainder of this Agreement shall continue in full force and effect. Any disputes arising under this Agreement shall be resolved by trial to a judge as the finder of fact
seated in a court of competent subject matter jurisdiction in San Mateo or San Francisco counties, California. Each party hereby consents to, and waives any defenses that party may have to or conflicting with, the personal jurisdiction and venue of
all such courts or relating to trial to a judge (including without limitation the defense of forum non conveniens). 
  

 6 

 14. COMPLETE UNDERSTANDING;
MODIFICATION. This Agreement constitutes the final, exclusive and complete understanding and agreement of the Company and Consultant with respect to the subject matter hereof. There are no other understandings,
agreements, representations or warranties between the parties with respect to that subject matter other than those set forth in this Agreement. Any waiver, modification or amendment of any provision of this Agreement shall be effective only if in
writing and signed by a Company officer. 
 15. NOTICES. Any notices required or permitted
hereunder shall be given to the appropriate party at the address specified below or at such other address as the party shall specify in writing. Such notice shall be deemed given upon personal delivery to the appropriate address or sent by certified
or registered mail, three days after the date of mailing. Either party may update its notice address by written notice to the other party. 
  

			
	 If to the Company:
	  	 If to the Consultant:

		
	 Kosan Biosciences Incorporated
 3832 Bay Center Place
 Hayward, CA 94545
 Attention: Chief Executive Officer
	  	 Margaret A. Horn
 [Address]

 IN WITNESS WHEREOF, the parties hereto have
executed this Agreement as of the date first set forth above. 
  

					
	KOSAN BIOSCIENCES INCORPORATED	 		 	MARGARET A. HORN
			
	/s/ Robert G. Johnson, Jr.	 		 	/s/ Margaret A. Horn
			
	PRINTED NAME: Robert G. Johnson, Jr.	 		 	PRINT NAME: Margaret A. Horn
			
	TITLE: President & CEO	 		 	SOCIAL SECURITY NUMBER:____________________

  

 7 

 EXHIBIT A 
 WORK PLAN; COMPENSATION 
 Work Plan: 
 Consultant will provide general consulting services as requested from time to time. Consultant’s primary contact at the Company shall be Robert G. Johnson, M.D.,
Ph.D., President and Chief Executive Officer. 
 Term of Service: 
 Until January 3, 2008, unless earlier terminated in accordance with this Agreement, or extended by mutual written agreement of Consultant and an officer of the Company. 
 Compensation: 
 Consultant shall be paid $250 per hour actually spent performing the Services (excluding de
minimis Services), not to exceed ten (10) hours per month without the Company’s prior written approval. Payments will be processed within thirty (30) days after receipt by Company of Consultant’s itemized invoice therefor
(which invoice shall contain a written description of the day(s) that Consultant provided services, the amount of time, and a description of the provided services with respect to all time invoiced). 
 Stock Option Awards: 
 Consultant and the Company agree to the
following regarding the stock option grants (the “Options”) provided to Consultant in connection with Consultant’s former employment with the Company: 
 To the maximum extent consistent with the Company’s 2006 Equity Incentive Plan (the “2006 Plan”) and Consultant’s option agreement(s) under the 2006 Plan, Consultant’s service to the Company
under the Consulting Agreement shall constitute “Continuous Service” (as defined in the 2006 Plan) and vesting of the Options under the 2006 Plan will continue so long as there is no termination or interruption of Consultant’s
Continuous Service. Once a termination or interruption of Consultant’s Continuous Service occurs (which will be no later than the termination of the Consulting Agreement), then Consultant will be entitled to exercise any vested shares subject
to the Options under the 2006 Plan within ninety (90) days thereafter (but in no event later than the expiration of the term of such Option as set forth in the option agreement(s)) pursuant to the terms and conditions of the 2006 Plan and
Consultant’s option agreement(s). 
 To the maximum extent consistent with the Company’s 1996 Stock Option Plan (the “1996 Plan”) and
Consultant’s option agreement(s) under the 1996 Plan, Consultant’s service to the Company under the Consulting Agreement shall result in Consultant being a “Service Provider” (as defined in the 1996 Plan) and vesting of the
Options under the 1996 Plan will continue so long as there is no termination or interruption of Consultant’s status as a Service Provider. Once a termination or interruption of Consultant’s status as a Service Provider occurs (which will
be 

 
no later than the termination of the Consulting Agreement), then Consultant will be entitled to exercise any vested shares subject to the Options under the
1996 Plan within such period of time as is specified in the Consultant’s option agreement(s) under the 1996 Plan (but in no event later than the expiration of the term of such Option as set forth in the option agreement(s)) pursuant to the
terms and conditions of the 2006 Plan and Consultant’s option agreement(s). In the absence of a specified time in the option agreement(s), any Options under the 1996 Plan shall remain exercisable for three (3) months following the
termination or interruption of Consultant’s status as a Service Provider.

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