Document:

LETTER AGREEMENT

 EXHIBIT 10.2 
  
 LETTER AGREEMENT 
  
 April 1, 2004 
  
 Baxter Healthcare Corporation 
 One Baxter Parkway 
 Deerfield, Illinois 60015 
 (“Baxter”) 
  

	 	Re:	Assumption of Liability for Refurbishment Obligations and Repayment Obligation 

  
 Ladies and Gentlemen: 
  
 The undersigned, Insmed Incorporated (“Insmed”), hereby acknowledges and agrees to the following: 
  
 1. In order to induce (a) 2545 Central, LLC, a Colorado limited liability
company (the “Landlord”) to terminate a lease with Baxter for the premises located at 2590 Central Avenue, Boulder, Colorado 80301 (the “Premises”) and enter into a lease with Insmed for the Premises (the “Insmed
Lease”) and (b) Insmed to enter into the Insmed Lease, Baxter agreed to maintain primary liability for the performance of certain refurbishment obligations with respect to the Premises (the “Refurbishment Obligation”) in the event
Insmed does not either exercise an option to renew the Insmed Lease, or, in lieu thereof, perform certain refurbishment obligations pursuant to the Insmed Lease. 
  
 2. In consideration of Baxter’s agreements referenced above, Insmed hereby agrees as follows: 
  
 3. In the event Baxter is required to satisfy any portion or all of the
Refurbishment Obligation, Insmed agrees to pay to Baxter upon written demand delivered by Baxter to Insmed at the notice address for Insmed set forth in the Insmed Lease, any and all reasonable costs, fees and expenses incurred by Baxter in
connection with satisfying the Refurbishment Obligation as set forth in the notice. 
  
 4. Simultaneously with delivering any notice to the Landlord under the Insmed Lease, including, without limitation, any notice indicating Insmed’s intent to exercise its option to renew the Insmed Lease, Insmed
shall deliver a copy of such notice to Baxter at: 
  
 Baxter Healthcare Corporation 
 One Baxter Parkway 
 Deerfield, Illinois 60015 
 Attn: Director or Real Estate, Mail Stop: DF4-3E 
  
 5. If Insmed does not exercise its option to renew the Insmed Lease prior to July 1, 2007, then Insmed shall commence performance of the Refurbishment Obligation on or prior to August 1, 2007, and diligently pursue
completion of the Refurbishment Obligation in accordance with the Insmed Lease on or before February 28, 2008. 

 6. If Insmed elects to exercise its option to renew the Insmed Lease prior to July 1, 2007, Insmed shall
perform the obligations of the Insmed Lease for the duration of such renewal term. 
  
 7. In addition to the specific obligations set forth above, Insmed shall not engage in any act or omission which would cause Landlord to seek payment of the Refurbishment Obligation from Baxter. 
  
 8. Simultaneously herewith, Insmed has caused the issuance of an Irrevocable
Letter of Credit in the amount of $2,000,000.00 USD to Baxter to secure the full performance of Insmed’s obligations as set forth herein (a copy of which is attached hereto as Exhibit A, the “Letter of Credit”). Thirty days prior to
each anniversary of the date hereof, Insmed shall deliver a replacement Letter of Credit at an amount which is escalated by 5%, which replacement Letter of Credit shall be effective upon such anniversary date (at which time the prior Letter or
Credit shall expire). Baxter shall have the right to present the Letter of Credit for full or partial payment to cover Baxter’s liability for any remaining Refurbishment Obligation as set forth in the Insmed Lease upon (i) Insmed’s failure
to exercise its option to renew the Insmed Lease by July 1, 2007 or Insmed’s failure to place a separate letter of credit to cover the expected refurbishment costs at the end of the Insmed Lease renewal period in accordance with the Insmed
Lease and the occurrence of any of the following events, which shall constitute a default hereunder, unless remedied by Insmed within 30 days of written notification by Baxter: (ii) Insmed shall fail to commence the Refurbishment Obligation on or
prior to August 1, 2007; or (iii) Insmed shall fail to satisfactorily complete the Refurbishment Obligation in accordance with the Insmed Lease; or (iv) Insmed shall otherwise engage in any act or omission that causes the Landlord to seek payment
from Baxter for the Refurbishment Obligation; or (v) Insmed shall fail to comply with its payment obligation as set forth in paragraph 5 of this Letter Agreement; or (vi) Insmed shall fail to perform any other material obligation hereunder.

  
 In the event an order of relief under title 11 of the United States Code shall
be entered against Insmed or any other insolvency, administrative or receivership proceeding or assignment for the benefit of creditors, whether under U.S. or non-U.S. law, or state or federal law, shall be commenced against or by Insmed and Insmed
is unable to provide Baxter with satisfactory evidence (to be determined in Baxter’s sole discretion) that it will be able to fulfill the material obligations of this letter Agreement within 30 days of the order of relief, Baxter shall have the
right to present the Letter of Credit for full or partial payment to cover Baxter’s liability for any remaining Refurbishment Obligation as set forth in the Insmed Lease. 
  
 9. The foregoing acknowledgements and agreements constitute agreements separate and apart from the Insmed Lease and shall
survive any termination of the Insmed Lease and shall continue for a period terminating on the earlier to occur of: (i) Insmed’s renewal of the Insmed Lease and placement of a separate letter of credit to cover the expected refurbishment costs
at the end of the Insmed Lease renewal period in accordance with the Insmed Lease; or (ii) completion of the Refurbishment Obligation in 

 accordance with the Insmed Lease; or (iii) payment of the full amount of the outstanding Refurbishment Obligations, not
to exceed $2,000,000.00 USD, from Insmed to Baxter for Insmed’s Refurbishment Obligations set forth herein and in the Insmed Lease. 
  
 10. This Letter Agreement shall be binding upon Insmed and for the benefit of Baxter, its successors and assigns. Insmed may not assign this Letter
Agreement without prior written consent of Baxter, which consent shall not be unreasonably withheld. Any assignment by Insmed of its obligations hereunder shall not relieve Insmed from primary liability to Baxter (or its successor and assigns)
therefor. Failure of Baxter to enforce any provision of this Letter Agreement shall not constitute a waiver of any term hereof by Baxter. 
  
 11. This Letter Agreement shall be governed by and construed and enforced in accordance with the internal laws of the State of Illinois, and shall be
binding upon the obligor and beneficiary of this Letter Agreement in the United States and worldwide. The federal and state courts within the State of Illinois shall have exclusive jurisdiction to adjudicate any dispute arising out of this
Agreement. 
  
 [Signatures Follow] 

 IN WITNESS WHEREOF, this Letter Agreement is executed and delivered as of the date first above written.

  

			
	 Obligor:
	 	 
	
	 Insmed Incorporated, a Virginia Corporation

	
	 By: ____________________________

	
	 Printed Name: ____________________

	
	 Title: ____________________________

  

	
	 Acknowledged:

	
	 Baxter Healthcare Corporation

	
	 By: ________________________

	
	 Printed Name : ________________

	
	 Title: ________________________Master Executive Employment Agreement - Steve Zhang Dated April 1, 2004

 Exhibit 10.10 
  
 MASTER EXECUTIVE EMPLOYMENT AGREEMENT 
  
 Dear Steve: 
  
 This Master Executive Employment Agreement, dated as of March 31, 2004 (this “Agreement”), is made and entered into by and between you and AsiaInfo Holdings, Inc., a Delaware corporation (the
“Company”). For purposes of this Master Agreement, “Group” means the Company and any direct or indirect subsidiaries of the Company. 
  

	1.	 	Purpose of this Agreement and the Supplementary Agreements 

  

	1.1.	 	The purpose of this Agreement is to set forth certain principal terms and conditions that apply to all of the employment services you render to the Company and other members of the
Group, either directly or pursuant to secondments or similar arrangements. Your employment shall also be governed from time to time by certain additional written agreements entered into between you and the Company or other members of the Group
(hereinafter “Supplementary Agreements”), as well as the written policies of the Company and the Group. The term of your employment, along with your salary and benefits and the provisions relevant to the termination of your
employment by you or the Group are set forth in the Supplementary Agreements. Any of the Supplementary Agreements may be terminated, modified or amended from time to time in accordance with their respective terms. In the event of any conflict
between the terms of any such Supplementary Agreement and the terms hereof, the terms hereof shall govern. 

  

	1.2.	 	Currently, the Supplementary Agreements in effect between you and the Company are as follows: 

  

	 	(a)	 	the letter agreement between you and the Company, dated October 18, 1999 (the “Letter Agreement”); 

  

	 	(b)	 	the Labor Contract between AsiaInfo Technologies (China), Inc., a company organized under the laws of the People’s Republic of China (“AsiaInfo Technologies”)
and you, dated March 14, 2001 (the “Labor Contract”); and 

  

	 	(c)	 	the Change of Control Agreement between you and the Company dated as of the date hereof. 

  

	2.	 	Confidential Information and Inventions 

  
 You agree to comply strictly with the confidentiality and invention assignment provisions attached to this Agreement as Appendix I. 
  

	3.	 	Non-Competition 

  

	3.1.	 	You acknowledge that: 

  

	 	(a)	 	you possess skills that are special, unique or extraordinary; 

  

	 	(b)	 	the level of compensation and the provisions in the Supplementary Agreements for compensation are partly in consideration of and conditioned upon your not competing with the Group;

  

	 	(c)	 	the provisions of this Clause 3 are essential to protect the business and goodwill of the Group. 

  

	3.2.	 	You agree that during your employment with the Group, and for a period of six (6) months thereafter (the “Covenant Period”) you will not render services for any
organization, or engage directly or indirectly in any other employment, business, or business related activity unless you receive the prior written approval of the Company’s Board of Directors (the “Board”) to hold such outside
employment or engage in such business or activity. Such written approval will not be unreasonably withheld if such outside employment, business or activity would not in any way be competitive with the business or proposed business of the Group or
otherwise conflict with or adversely affect in any way your performance of your employment obligations to the Group. 

  

	3.3.	 	You agree that, during your employment, you shall devote substantially all your business efforts and time to the Group. You further agree that, during your employment, you will not
actively engage in any other employment, occupation or consulting activity for any direct or indirect remuneration without the prior approval of the Board; provided, however, that you may: 

  

	 	(a)	 	serve in any capacity with any professional, community, industry, civic, educational or charitable organization; 

  

	 	(b)	 	serve as a member of corporate boards or directors on which you currently serve and, with the consent of the Board (which consent shall not be unreasonably withheld or delayed),
other corporate boards of directors; and 

  

	 	(c)	 	manage your personal investments and legal affairs so long as such activities do not materially interfere with the discharge of your duties to the Group. 

 

	3.4.	 	You agree that during your employment and the Covenant Period, except as provided below, you will not: 

  

	 	(a)	 	accept employment with or render services or advice to any organization, or engage, directly or indirectly in any business that competes with the business of the Group in any
province in the People’s Republic of China (the “PRC”) where the Group is physically located or in which it generates more than 5% of its China revenues, as well as all areas of Hong Kong, Macau and Taiwan;

  

	 	(b)	 	become an owner of any company which provides products or services that are competitive with those offered or planned by the Group, including, but not limited to, companies offering
system integration services or telecommunications infrastructure software products in the PRC, Hong Kong, Macau or Taiwan (the business activities referred to in this paragraph will hereinafter be referred to as the “Business”); or

  

	 	(c)	 	directly or indirectly disrupt, damage or interfere with the operation or business of the Group by soliciting, recruiting, diverting, taking away or otherwise interfering with any
customers or clients of the Group; or 

  

	 	(d)	 	directly or indirectly solicit or encourage any employee or consultant of the Group to terminate his or her employment or engagement, or to accept employment or an engagement with
any other company. 

  

	3.5.	 	Notwithstanding the foregoing, you may own, directly or indirectly, solely as an investment, up to, but not more than, one percent (1%) of any class of “publicly traded
securities” of any company engaged in the Business. The term “publicly traded securities” shall mean securities that are traded on an internationally-recognized securities exchange. 

  

	3.6.	 	If any restriction set forth in this Clause is found by a court or arbitrator to be unenforceable by reason of its extent, duration, geographical scope or for any other reason, then
you agree, and hereby submit, to the reduction and limitation of such prohibition to such extent, duration, geographical scope or other provision as shall be deemed enforceable. 

  

	3.7.	 	You acknowledge that irreparable harm will be suffered by the Company in the event of the breach by you of any of your obligations under this Agreement, and that the Company will be
entitled, by reason of such breach or any threatened breach, to enforce by an injunction or decree of specific performance the obligations set forth in this Agreement, in addition to the Company’s other rights. Any claims asserted by you
against the Company shall not constitute a defense in any injunction action brought by the Company to obtain specific enforcement. 

  

	4.	 	Arbitration 

  

	4.1.	 	 You agree that any dispute or controversy arising out of or in any way concerning this Agreement or your employment with the Company or any other member of the
Group, shall be submitted to a single arbitrator appointed by the Hong Kong International Arbitration Center. The 

	 	 
arbitration shall be conducted in Hong Kong in accordance with the then applicable arbitration rules of the United Nations Commission on International Trade
Law and the language used in the arbitral proceedings shall be English. The arbitration award shall be final, conclusive and binding on the parties to the arbitration. Judgement may be entered on the arbitration award in any court having
jurisdiction. The Company and you shall each pay one-half of the costs and expenses of such arbitration, and each party shall separately pay its counsel’s fees and expenses. Notwithstanding this arbitration clause, the parties may apply for
injunctive relief to any court with jurisdiction. 

  

	4.2.	 	You understand that each party’s promise to resolve claims by arbitration in accordance with the provisions of this Agreement, rather than through the courts, is consideration
for the other party’s like promise. 

  

	5.	 	Miscellaneous Provisions 

  
 This Agreement and the Supplemental Agreements represent the entire agreement among you, the Company and the other members of the Group relating to your
employment and the additional matters provided for herein and therein. This Agreement may be amended or altered only in a writing signed by you and the Company. 
  

This agreement shall be construed and interpreted in accordance with the laws of the State of Delaware. Each provision of this Agreement is severable
from the others, and if any provision hereof shall be to any extent unenforceable it and the other provisions shall continue to be enforceable to the full extent allowable, as if such offending provision had not been a part of this Agreement.

  
 Sincerely, 
  

			
	ASIAINFO HOLDINGS, INC.
		
	 By:
	 	 /s/    XINGSHENG ZHANG

	 	 	 Name: Xingsheng Zhang

	 	 	 Title: President and Chief Executive Officer

  
 I agree to and accept the terms and
conditions of this Agreement. 
  

	
	
	 /s/    STEVE ZHANG

	

	 Steve Zhang

 APPENDIX I 
 CONFIDENTIAL INFORMATION AND INVENTIONS 
  
 For purposes of this Appendix, the “Company” means AsiaInfo Holdings, Inc., a Delaware corporation, and the “Group” means the Company and any direct or indirect subsidiary of the
Company. 
  

	1.	 	Confidential Information. 

  
 (a) Company Information. I agree at all times during the term of my employment and thereafter, to hold in strictest confidence, and not to use,
except for the benefit of the Company or the benefit of the Group, or to disclose to any person, firm or corporation without written authorization of the Board of Directors of the Company, any Confidential Information (as hereafter defined). I
understand that “Confidential Information” means any proprietary information, technical data, trade secrets or know-how, including, but not limited to, research, product plans, products, services, customer lists and customers
(including, but not limited to, customers of the Company and/or any other member of the Group on whom I called or with whom I became acquainted during the term of my employment), partners, markets, software, developments, inventions, processes,
formulas, technology, designs, drawings, engineering, hardware configuration information, yield data, equipment modifications, pricing, marketing, finances or other business information of the Group disclosed to me by or obtained by me from the
Company and/or any other member of the Group either directly or indirectly in writing, orally or by drawings or observation of parts or equipment. I further understand that Confidential Information does not include any of the foregoing items which
has become publicly known and made generally available through no wrongful act of mine or of others who were under confidentiality obligations as to the item or items involved. 
  
 (b) Former Employer Information. I agree that I will not, during my employment with the Company, improperly use or
disclose any proprietary information or trade secrets of any former or concurrent employer or other person or entity and that I will not bring onto the premises of the Company and/or any other member of the Group any unpublished document or
proprietary information belonging to any such employer, person or entity unless consented to in writing by such employer, person or entity. I agree to indemnify the Company and/or any other member of the Group and hold it or them harmless from all
claims, liabilities, damages and expenses, including reasonable attorneys fees and costs of litigation, arising out of or in connection with any violation or claimed violation of a third party’s rights resulting from any use by the Company
and/or any other member of the Group of such proprietary information or trade secrets improperly used or disclosed by me. 
  
 (c) Third Party Information. I recognize that the Company and other members of the Group have received and in the future will receive from third
parties their confidential or proprietary information subject to a duty on the Company’s part or the part of other members of the Group to maintain the confidentiality of such information and to use it only for certain limited purposes. I agree
to hold all such confidential or proprietary information in the strictest confidence and not to disclose it to any person, firm or corporation or to use it except as necessary in carrying out my work for the Company consistent with the
Company’s agreement with such third party. 
  

	2.	 	Inventions. 

  
 (a) Assignment of Inventions. I agree that I will promptly make full written disclosure to the Company, will hold in trust for the sole right and
benefit of the Company, and hereby assign to the Company, or its designee, all my right, title, and interest in and to any and all inventions, original works of authorship, developments, concepts, improvements, designs, discoveries, ideas,
trademarks or trade secrets, processes, copyright works, know-how, any other work’s information or matter which gives rise or may give rise to any intellectual property of whatsoever nature, whether or not patentable or registrable under any
law of any country, which I may solely or jointly conceive or develop or reduce to practice, or cause to be conceived or developed or reduced to practice, during the period of time I am in the employ of the Company (collectively referred to as
“Inventions”), except as provided in Section 2(e) below. I acknowledge that the Company, or its designee, has 

  

 
the absolute title, right or interest in and to any and all original inventions or works of authorship which are made by me, as an employee, (solely or
jointly with others) within the scope of and during the period of my employment with the Company. I understand and agree that the decision whether or not to commercialize or market any invention developed by me solely or jointly with others is
within the Company’ sole discretion and for the sole benefit of the Company and/or any other member of the Group, and that no royalty will be due to me as a result of the Company’s efforts (or the efforts of any member of the Group) to
commercialize or market any such Invention. 
  
 (b) Maintenance
of Records. I agree to keep and maintain adequate and current written records of all Inventions made by me (solely or jointly with others) during the term of my employment with the Company. The records will be in the form of notes, sketches,
drawings, and any other format that may be specified by the Company. The records will be available to and remain the sole property of the Company at all times. 
  

(c) Patent and Copyright Registrations. I agree to assist the Company, or its designee, at the Company’s expense, in every proper way to
secure the Company’s (or its designee’s) rights in the Inventions and any copyrights, patents, mask work rights or other intellectual property rights relating thereto in any and all countries, including the disclosure to the Company of all
pertinent information and data with respect thereto, the execution of all applications, specifications, oaths, assignments and all other instruments which the Company shall deem necessary in order to apply for and obtain such rights and in order to
assign and convey to the Company, its successors, assigns, and nominees the sole and exclusive rights, title and interest in and to such Inventions, and any copyrights, patents, mask work rights or other intellectual property rights relating
thereto. I further agree that my obligation to execute or cause to be executed, when it is in my power to do so, any such instrument or papers shall continue after the termination of my employment with the Group for any reason. If the Company or its
designee is unable because of my mental or physical incapacity or for any other reason to secure my signature to apply for or to pursue any application for any United States or foreign patents or copyright registrations covering Inventions or
original works of authorship assigned to the Company as above, then I hereby irrevocably designate and appoint the Company and its duly authorized officers and agents as my agent and attorney in fact, to act for and in my behalf and stead to execute
and file any such applications and to do all other lawfully permitted acts to further the prosecution and issuance of letters patent or copyright registrations thereon with the same legal force and effect as if executed by me. 
  

	3.	 	Returning Company Documents. 

  
 I agree that, at the time of leaving the employ of the Company, I will deliver to the Company (and will not keep in my possession, recreate or deliver to
anyone else) any and all devices, records, data, notes, reports, proposals, lists, correspondence, specifications, drawings blueprints, sketches, materials, equipment, other documents or property, or reproductions of any aforementioned items
developed by me pursuant to my employment with the Company or otherwise belonging to the Company and/or any other member of the Group.

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