Document:

exv10w1

January 23, 2009

Stephen DiPalma

RXi Pharmaceuticals Corporation

60 Prescott St.

Worcester, MA 01609

Subject: RXi Pharmaceuticals/Newgate Properties Lease Amendment

Dear Steve,

Per your discussion with D’ Anne Hurd, Vice President for Business Development at Gateway
Park (Newgate Properties, LLC), this letter is to serve as an amendment to the Lease between
RXi Pharmaceuticals Corporation and Newgate Properties, LLC dated September 25,2007.

Landlord and Tenant agree to amend Section 1.1 , Term, to extend the Term for an additional
two (2) years beginning August I, 2009. Therefore, the Lease will now expire on July 31, 2011.

Tenant and Landlord agree to amend Section 1.1, Term to allow Tenant the right to terminate
the Lease as may be specified by at least
sixty (60) days’ notice to Landlord.

All other Lease terms including those contained in the amendments dated August 28, 2008 and
November 4, 2008 will remain in full force and effect.

By signing this letter, we agree to the above terms.

Very truly yours,

LANDLORD:

Newgate Properties, LLC

	 	 	 	 	 
	By:  	/s/ D’Anne Hurd
 	 
	D’ Anne Hurd, Vice President and General Counsel 	 
	Worcester Polytechnic Institute 	 

TENANT:

RXi Pharmaceuticals Corporation

Acknowledged and Agreed to as of this 23rd day of January, 2009

	 	 	 	 	 
	By:  	/s/ Stephen DiPalma
 	 
	Stephen DiPalma, EVP and CFO 	 
	RXi Pharmaceutical Corporationexv10w1

   Exhibit
10.1

 

    AMENDMENT
    NO. 1 TO AMENDED AND RESTATED 2005 SYNERGETICS USA, INC.
    NON-EMPLOYEE
    DIRECTORS’ STOCK OPTION PLAN

 

    2005
    NON-EMPLOYEE DIRECTORS’ STOCK OPTION PLAN

 

    RECITALS

 

    WHEREAS, the Board of Directors and stockholders of Synergetics
    USA, Inc. (the “Company”) previously approved the
    Amended and Restated Synergetics USA, Inc. 2005 Non-Employee
    Directors’ Stock Option Plan (the “Plan”);

 

    WHEREAS, the Board of Directors is authorized to administer and
    amend the Plan, subject to stockholder approval as may be
    required pursuant to rules of the national securities exchange
    on which the Company’s Common Stock is listed;

 

    WHEREAS, the Board of Directors desires to amend the Plan,
    effective as of October 7, 2008.

 

    NOW, THEREFORE, effective as of October 7, 2008, the Plan
    is amended as follows:

 

    AMENDMENT

 

    1. Section 3 of the Plan shall be amended to read in
    its entirety as follows:

 

    3. Shares and Options.  The maximum number
    of Shares to be issued pursuant to Options under this Plan shall
    be FOUR HUNDRED THOUSAND (400,000) Shares. Shares issued
    pursuant to Options granted under this Plan may be issued from
    Shares held in the Company’s treasury or from authorized
    and unissued Shares. If any Option granted under this Plan shall
    terminate, expire or be canceled or surrendered as to any
    Shares, new Options may thereafter be granted covering such
    Shares. Any Option granted hereunder shall be a Nonstautory
    Stock Option.

 

    IN WITNESS WHEREOF, this Amendment No. 1 was duly adopted
    by the Board of Directors of the Company as of October 7,
    2008.

 

    Executed this
    7th day

    of October, 2008.

 

			
	 	    By: 
	
    

     Pamela G. Boone, Secretary

    

    A-1exv10w1

Exhibit 10.1

Amendment No. RI0475B

AMENDMENT

TO THE

MASTER LOAN AGREEMENT

     THIS AMENDMENT is entered into as of December 24, 2008, between FARM CREDIT SERVICES OF
AMERICA, FLCA (“Farm Credit”) and ABE FAIRMONT, LLC, Fairmont, Nebraska (the “Company”).

BACKGROUND

     Farm Credit and the Company are parties to a Master Loan Agreement dated November 20, 2006
(such agreement, as previously amended, is hereinafter referred to as the “MLA”). Farm Credit and
the Company now desire to amend the MLA. For that reason, and for valuable consideration (the
receipt and sufficiency of which are hereby acknowledged), Farm Credit and the Company agree as
follows:

1. Section 9(H)(viii) of the MLA is hereby amended and restated to read as follows:

     SECTION 9. Affirmative Covenants. Unless otherwise agreed to in writing by Agent while this
agreement is in effect, the Company agrees to, and with respect to Subsections 9(B) through 9(G)
hereof, agrees to cause each Subsidiary to:

          (H) Reports and Notices. Furnish to Agent:

               (viii) Compliance Certificate. Together with each set of financial statements furnished to
Agent pursuant to Subsection (H)(ii) hereof, a certificate of an officer of employee of the Company
acceptable to Agent, in the form attached as Exhibit “A” hereto: (a) certifying that no Event of
Default or Potential Default occurred during the period covered by such statement(s) or, if an
Event of Default or Potential Default occurred, a description thereof and of all actions taken or
to be taken to remedy same, and (b) setting forth calculations showing compliance with the
financial covenants set forth in Section 11 hereof.

2. Section 10(I) of the MLA is hereby amended and restated to read as follows:

     SECTION 10. Negative Covenants. Unless otherwise agreed to in writing by Agent, while this
agreement is in effect the Company will not:

          (I) Leases. Create, incur, assume, or permit to exist any obligation as lessee under
operating leases or leases which should be capitalized in accordance with GAAP for the rental or
hire of any real or personal property, except for: (i) leases which do not in the aggregate
require the Company to make scheduled payments to the lessors in any fiscal year of the Company in
excess of $100,000.00; and (ii) leases of railroad cars, provided, however, the Company will lease
no more than 454 cars, and further provided that all railroad car leases expire on or before
December 1, 2013, and with any subsequent extension or renewal of any railroad car lease not to
exceed a term of three years, all under terms and conditions acceptable to Agent.

 

 

			
	Amendment RI0475B to Master Loan Agreement RI0475
	 	-2-
	ABE FAIRMONT, LLC	 	 
	Fairmont, Nebraska	 	 

3. Section 11(B) of the MLA is hereby amended and restated to read as follows:

     SECTION 11. Financial Covenants. Unless otherwise agreed to in writing, while this agreement
is in effect:

          (B) Net Worth. The Company will have at the end of each period for which financial statements
are required to be furnished under Section 9(H) hereof an excess of total assets over total
liabilities (both as determined in accordance with GAAP consistently applied) of not less than:
(i) $51,000,000.00 as of December 31, 2008; (ii) increasing to $52,000,000.00 as of March 31, 2009;
and (iii) increasing to $54,000,000.00 as of September 30, 2009 and thereafter, except that in
determining total liabilities, the amount of Tax Increment Financing shall be excluded.

4. Except as set forth in this amendment, the MLA, including all amendments thereto, shall continue
in full force and effect as written.

     IN WITNESS WHEREOF, the parties have caused this amendment to be executed by their duly
authorized officers as of the date shown above.

	 	 	 	 	 	 	 	 	 
	FARM CREDIT SERVICES	 	 	 	ABE FAIRMONT, LLC
	OF AMERICA, FLCA	 	 	 	     By ADVANCED BIOENERGY, LLC,
	 	 	 	 	 	 	     its sole member
	By:

	 	/s/ Shane Frahm	 	 	 	By:	 	/s/ Richard Peterson
	 

	 	 
	 	 	 	 	 	 
	 
	 	 	 	 	 	 	 	 
	Title:

	 	Vice President	 	 	 	Title:	 	CEO/CFO
	 

	 	 
	 	 	 	 	 	 

 

 

EXHIBIT A

FARM CREDIT SERVICES OF AMERICA, FLCA

COMPLIANCE CERTIFICATE

     This certificate is being furnished to CoBANK, ACB (“CoBank”), as agent for Farm Credit
Services of America, FLCA (“Farm Credit”) to induce CoBank to make and/or continue to make advances
to the Company and to comply with and demonstrate compliance with the terms, covenants, and
conditions of the Company’s Master Loan Agreement and all Supplements thereto. The undersigned
hereby certifies that: (i) this certificate was prepared from the books and records of the Company,
is in agreement with them, and is correct to the best of the undersigned’s knowledge and belief;
(ii) no “Event of Default” (as defined in the Master Loan Agreement) or event which, with the
giving of notice and/or the passage of time and/or the occurrence of any other condition, would
ripen into an Event of Default (a “Potential Default”) shall have occurred and be continuing,
except as disclosed below; and (iii) based upon the undersigned’s review of the attached financial
statement(s) dated as of                                         , to the best of the undersigned’s knowledge, the
attached financial statement(s) are accurate and complete for the period reflected. Each of the
following Financial Covenants shall have the meanings ascribed thereto in Section 11 of the
Company’s Master Loan Agreement.

     This certificate is attached to and made a part of the Company’s financial statements for the
reporting period ending                                         .

	 	 	 	 	 	 	 	 	 	 	 
	FINANCIAL	 	TARGET RESULT	 	 	 	 
	COVENANT	 	REQUIRED	 	CALCULATION(S)	 	ACTUAL
	Working Capital
	 	$	10,000,000.00	 	 	 	 	$	                    	 
	 
	 	 	 	 	 	 	 	 	 	 
	Net Worth
	 	$	51,000,000.00	 	 	Monthly Effective 12/31/08	 	$	                    	 
	 
	 	$	52,000,000.00	 	 	Monthly Effective  3/31/09	 	 	 	 
	 
	 	$	54,000,000.00	 	 	Monthly Effective 9/30/09	 	 	 	 
	 
	 	 	 	 	 	 	 	 	 	 
	Debt Service
	 	 	1.25:1.00	 	 	Fiscal Year End Effective	 	 	                    	 
	Coverage Ratio
	 	 	 	 	 	FYE 2008	 	 	 	 

OTHER COMMENTS, INCLUDING A DESCRIPTION OF ANY DEFAULTS AND CORRECTIVE ACTIONS BEING UNDERTAKEN:

 

 

	 	 	 
	 

	 	ABE FAIRMONT, LLC
	 

	 	By: ADVANCED BIOENERGY, LLC,
	 

	 	        its sole member
	 
	 	 
	 

	 	 
	 

	 	Authorized Signature
	 
	 	 
	 

	 	 
	Date

	 	Title

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