Document:

Exhibit 10.1

 

CERTAIN CONFIDENTIAL INFORMATION MARKED BY [*]
HAS BEEN EXCLUDED FROM THE EXHIBIT BECAUSE IT BOTH IS NOT MATERIAL AND IS THE TYPE THAT THE REGISTRANT CUSTOMARILY AND ACTUALLY TREATS
AS PRIVATE OR CONFIDENTIAL.

 

EXCLUSIVE LICENSE AND SUPPLY AGREEMENT

 

THIS EXCLUSIVE LICENSE AND
SUPPLY AGREEMENT (“Agreement”) is made effective as of the 7th day of April, 2022 (the “Effective Date”),
by and between Immedica Pharma AB, a corporation organized and existing under the laws of Sweden with registration number, 556835-6322
and offices at Norrtullsgatan 15, SE 113 29 Stockholm, Sweden (“IMMEDICA”) and Actinium Pharmaceuticals, Inc., a corporation
organized and existing under the laws of Delaware and with offices at 275 Madison Avenue, 7th Floor, New York, NY 10016, U.S.A. (“LICENSOR”).
IMMEDICA and LICENSOR may, from time-to-time, be individually referred to as a “Party” and collectively referred
to as the “Parties”.

 

RECITALS

 

WHEREAS, LICENSOR Controls the Licensed Technology
(hereinafter defined); and

 

WHEREAS, IMMEDICA wishes to obtain, and LICENSOR
wishes to grant, certain licenses under the Licensed Technology on the terms and conditions set forth herein.

 

NOW, THEREFORE,
in consideration of the mutual agreements and covenants set forth herein and other good and valuable consideration, the receipt and sufficiency
of which the Parties hereby acknowledge, the Parties, intending to be legally bound hereby, agree to the foregoing and as follows:

 

	1.	DEFINITIONS

 

	1.1.	“Additional Clinical Studies” has the meaning given in Section 4.2.1.

 

	1.2.	“Additional Indication Study” has the meaning given in Section 4.2.2.

 

	1.3.	“Additional Product” has the meaning given in Section 2.4.

 

	1.4.	“Affiliate” means, with respect to a Party, any Person that controls, is controlled
by, or is under common control with that Party. For the purpose of this definition, “control” shall refer to: (a) the
possession, directly or indirectly, of the power to direct the management or policies of an entity, whether through the ownership of voting
securities, by contract or otherwise, or (b) the ownership, directly or indirectly, of fifty percent (50%) or more of the voting securities
of such entity.

 

	1.5.	“Applicable Laws” means all applicable laws, statutes, rules, regulations and guidelines,
including, without limitation, all applicable standards or guidelines promulgated by any Regulatory Authority, including to the extent
applicable, GLP, GCP and GMP.

 

	1.6.	“AML” means Acute Myeloid Lukemia.

 

     

     

    

 

	1.7.	“Business Day” means any day other than a Saturday, a Sunday or a day on which commercial
banks located in New York, NY, U.S.A. or Sweden are authorized or required by law to remain closed.

 

	1.8.	“Calendar Quarter” means each period of three (3) consecutive months ending on March
31, June 30, September 30, or December 31.

 

	1.9.	“Calendar Year” means the period of twelve (12) consecutive months corresponding to
the calendar year commencing on the first day of January and ending on the last day of December, and each successive twelve (12) month
period thereafter.

 

	1.10.	“Claims” means collectively, any and all Third Party demands, claims, actions and proceedings
(whether criminal or civil, in contract, tort or otherwise) for losses, damages, liabilities, costs and expenses (including reasonable
attorneys’ fees).

 

	1.11.	“Clinical Studies” means any study in which human subjects are dosed or treated with
a drug or biological product, whether approved or investigational and including paediatric studies and investigator sponsored studies.

 

	1.12.	“Commercialize” or “Commercialization” means any and all activities related
to pre-marketing, launching, marketing, promotion (including advertising and detailing), serialization, bidding and listing, pricing and
reimbursement, distribution, storage, handling, offering for sale, selling, having sold, importing, having imported, exporting, having
exported, distributing, having distributed, supplying for named patient use, providing customer service and support, conducting medical
affairs, conducting post-marketing safety surveillance and reporting of or otherwise commercializing or exploiting the Product. “Commercializing”
has the correlative meaning.

 

	1.13.	“Commercially Reasonable Efforts” means that level of efforts that a similarly situated
biopharmaceutical company would normally use, in the exercise of its prudent scientific and business judgment, for the development and/or
commercialization of a comparable pharmaceutical product for a similar patient population at a similar stage of its development or commercialization,
taking into account all relevant scientific, commercial, business and other factors, including issues of safety and efficacy, expected
and approved product labeling, expected and actual cost and time to develop, expected and actual profitability, the nature and extent
of expected and actual market exclusivity (including patent coverage and regulatory exclusivity), the expected likelihood of marketing
approval, and the expected and actual amounts of marketing and promotional expenditures required. Commercially Reasonable Efforts shall
be determined on a country-by-country basis and it is anticipated that the level of effort and resources that constitute “Commercially
Reasonable Efforts” with respect to a particular country will change over time.

 

	1.14.	“Control” or “Controlled” means, with respect to any Intellectual Property
Rights, the legal authority or right (whether by ownership, license or otherwise) of a Party to grant the applicable access to, or a license
or a sublicense of or under, such Intellectual Property Rights to the other Party without breaching the terms of any agreement with a
Third Party existing as of the Effective Date, or at such later time as such Party first acquires rights to such subject matter.

 

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	1.15.	“Cover” means, with respect to a compound, product, technology, process or method,
that in the absence of ownership of or a license granted under a Valid Claim, the Manufacture, use, offer for sale, sale or importation
of such product or the practice of such technology, process or method would infringe such Valid Claim (or, in the case of a Valid Claim
that has not yet issued, would infringe such Valid Claim if it were to issue as then being prosecuted). “Covered by” has
the correlative meaning.

 

	1.16.	“Develop” or “Development” means to conduct any and all non-clinical and
clinical research and development activities, including non-clinical development, toxicology, pharmacology, statistical analysis, Clinical
Studies (including pre- and post-approval studies), regulatory affairs, and regulatory activities pertaining to designing and carrying
out clinical studies and all activities necessary to obtain Regulatory Approval.

 

	1.17.	“EMA” means the European Medicines Agency or any successor agency thereto.

 

	1.18.	“Executive Officers” means with respect to each Party, the chief executive officer of such Party or another senior
officer designated by such chief executive officer.

 

	1.19.	“Existing Agreements” means the [*].

 

	1.20.	“Facility” or “Facilities” shall mean the following GMP manufacturing facilities
utilized by LICENSOR or its Third Party contract manufacturers in the manufacture of the Product: [*].

 

	1.21.	“FDA” shall mean the United States Food and Drug Administration, or any successor agency
thereto.

 

	1.22.	“FDCA” shall mean the U.S. Federal Food, Drug and Cosmetic Act.

 

	1.23.	“Fees” means collectively, the upfront payment, all Milestone Payments, and Royalties.

 

	1.24.	“Field” means all uses in humans including the treatment of AML, bone marrow transplant
conditioning, non-myeloablative conditioning, and lymphodepletion.

 

	1.25.	“First Commercial Sale” means, on a country-by-country basis, the first sale for use,
or consumption, by the general public of the Product following receipt of all Regulatory Approvals for such Product in such country in
the Territory.

 

	1.26.	“Force Majeure Event” has the meaning set out in Section 19.5.

 

	1.27.	“Good Clinical Practice” or “GCP” means the current standards for clinical
studies for pharmaceuticals, as set forth in the ICH guidelines and applicable regulations promulgated thereunder, as amended from time
to time, and such standards of good clinical practice as are required by the European Union, to the extent such standards are not less
stringent than United States Good Clinical Practice.

 

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	1.28.	“Good Laboratory Practice” or “GLP” means the current standards for laboratory
activities for pharmaceuticals, as set forth in the FDA’s Good Laboratory Practice regulations or the Good Laboratory Practice principles
of the Organization for Economic Co-Operation and Development, as amended from time to time, and such standards of good laboratory practice
as are required by the European Union, to the extent such standards are not less stringent than United States Good Laboratory Practice.

 

	1.29.	“Good Manufacturing Practice” or “GMP” shall mean current good manufacturing
practice and standards as provided for (and as amended from time to time) in the Current Good Manufacturing Practice Regulations of the
U.S. Code of Federal Regulations Title 21 (21 CPR §§ 210, 211, 601 and 610) and the most recent approved edition of European
Commission Directives applicable to the production of pharmaceutical products, as interpreted by the ICH Harmonized Tripartite Guideline,
and related regulations or guidance documents subsequently established by any applicable governmental or regulatory authority in the United
States or European Union.

 

	1.30.	“Housemarks” shall mean the trade name Actinium Pharmaceuticals, Inc.

 

	1.31.	“lomab-B” means the pharmaceutical product known by that name comprising a CD45 directed
monoclonal antibody known as apamistamab linked to Iodine-131.

 

	1.32.	“Intellectual Property Rights” means all trade secrets, Know-How, copyrights, patents
and other patent rights, trademarks, moral rights, service marks, industrial designs, mask works, integrated circuit topographies, confidential
information, trade names, goodwill and any and all other intellectual property or proprietary rights now known or hereafter recognized
in any jurisdiction, whether registered or unregistered, and including rights in any application for any of the foregoing.

 

	1.33.	“Know-How” means all technical, scientific and other know-how and information, trade
secrets, knowledge, technology, means, methods, processes, practices, formulas, instructions, skills, techniques, procedures, ideas, technical
assistance, designs, drawings, assembly procedures, computer programs, apparatuses, specifications, data, results and other material,
including manufacturing procedures, test procedures, and purification and isolation techniques in written, electronic or any other form,
and all other discoveries, developments, inventions (whether or not patented or patentable), and tangible embodiments of any of the foregoing,
in each case that is not generally known to the public.

 

	1.34.	“Licensed Know-How” means all Know-How Controlled by LICENSOR or any of its Affiliates
as of the Effective Date or during the term of this Agreement that is necessary or useful for seeking and obtaining Regulatory Approval
for the Product in the Field in the Territory or for the Development or Commercialization of the Product in the Field in the Territory.

 

	1.35.	“Licensed Patents” means: (a) the patents and patent applications listed in Schedule
A, (b) all Patent Rights that claim priority to the patents or patent applications described in subsection (a), and (c) any other
Patent Rights Controlled by the LICENSOR or any of its Affiliates as of the Effective Date or during the term of this Agreement that Cover
the Development or Commercialization of a Product or that claim Licensed Know-How (including in each case all related Patent Rights as
described in clauses (a)-(e) of Section 1.43 below).

 

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	1.36.	“Licensed Technology” means collectively, the Licensed Patents and Licensed Know-How.

 

	1.37.	“Manufacture” and “Manufacturing” means all activities related to the synthesis,
making, production, processing, purifying, formulating, filling, finishing, packaging, labeling and shipping of any Product, or any intermediate
thereof, including process development, process qualification and validation, scale-up, pre-clinical, clinical and commercial production
and analytic development, product characterization, stability testing, quality assurance, and quality control. “Manufactured”
has the correlative meaning.

 

	1.38.	“Manufacturing Agreements” means those agreements entered into by or on behalf of the
LICENSOR or its Affiliates which relate to the manufacture of the Product or any part thereof, which is to be, or which has been, supplied
to IMMEDICA under this Agreement, including the associated drug substance and drug product manufacturing agreements. At the Effective
Date, the Manufacturing Agreements include (a) the Manufacturing Services Agreement, dated [*], between LICENSOR and [*], (b) the Agreement
for Services, dated [*], between LICENSOR and [*] and (c) the Radiochemical Supply Agreement, dated [*], between LICENSOR and [*].

 

	1.39.	“Materials” shall mean, excipients and solvents and other chemicals and other raw materials
(including the CD45 directed monoclonal antibody known as apamistamab) and components, packaging and shipping materials (including vials)
and other materials and supplies reasonably necessary to perform the Services.

 

	1.40.	“Milestone” means each milestone as set forth in Schedule B.

 

	1.41.	“Milestone Payment” has the meaning set out in Section 6.1.2.

 

	1.42.	“Net Sales” means the sales revenues received by or on behalf ofIMMEDICA and its Affiliates
and Sublicensees for sales of the Product to Third Parties, less the following deductions if and to the extent they are included in the
gross invoiced sales price of the Product or otherwise incurred by IMMEDICA and its Affiliates or Sublicensees with respect to the sale
of the Product: (a) rebates, quantity and cash discounts, and other usual and customary discounts to customers, (b) Taxes (but excluding,
for the avoidance of doubt, income taxes paid or payable by IMMEDICA, its Affiliates and Sublicensees with respect to such sales) and
any other duties paid, absorbed or allowed which are directly related to the sale of the Product, (c) credits, allowances, discounts and
rebates, and chargebacks for spoiled, damaged, out-dated, recalled, rejected or returned Product, (d) actual freight and insurance costs
incurred in transporting the Product to customers, (e) discounts or rebates or other payments required by Applicable Law, including any
governmental special medical assistance programs, and (f) customs duties, surcharges and other governmental charges and rebates incurred
in connection with the exportation or importation of the Product . Subsections (a) through (f) shall be collectively referred to as “Deductions”.

 

The following principles shall apply in the calculation
of Net Sales:

 

		1.42.1.	The provision of the Product at no charge for the purpose of conducting pre-clinical or clinical research,
or as donations or the like or as “treatment IND sales”, “named patient sales”, “compassionate use sales”,
or pursuant to any expanded access programs, or any equivalent sales, in each case shall not be deemed to be included in Net Sales.

 

		1.42.2.	Transfers of Product between IMMEDICA and its Affiliates and/or Sublicensees shall not be treated as Net
Sales for the purposes of this Agreement.

 

		1.42.3.	Unless otherwise specified herein, Net Sales shall be calculated in accordance with IMMEDICA’s,
or its Affiliate’s or Sublicensees’s applicable accounting practices generally and consistently applied.

 

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	1.43	“Other Product” has the meaning given in Section 2.4.

 

	1.44	“Patent Rights” means with respect to any patents or patent applications, any and all
(a) patents issuing from such patent applications, (b) substitutions, divisionals, renewals, continuations or continuations-in-part (only
to the extent of claims that are entitled to the priority date of the parent application); (c) patents of addition, restorations, extensions,
supplementary protection certificates, registration or confinnation patents, patents resulting from post-grant proceedings, re-issues
and re-examinations; (d) other patents or patent applications claiming and entitled to claim priority to (i) such patents and patent applications
and any patent or patent application specified in (a), (b) or (c), or (ii) any patent or patent application from which such patents and
patent applications or a patent or patent application specified in (a), (b) or (c) claims and is entitled to claim priority; (d) all rights
of priority attendant to such patents and patent applications and any of the patents and patent applications listed in (a) through (d);
and (e) in each case of such patents and patent applications and of the patents and patent applications described in (a) through (d),
including all counterparts and foreign equivalents thereof filed in any country, territory or jurisdiction in the world.

 

	1.45	“Person” means an individual, corporation, partnership, limited liability company,
trust, business trust, association, joint stock company, joint venture, pool, syndicate, sole proprietorship, unincorporated organization,
governmental authority or any other form of entity not specifically listed herein.

 

	1.46	“Phase III Clinical Trial” means the phase III clinical study of the Product titled
“Iomab-B (131-I apamistamab)” having ClinicalTrials.gov identifier NCT02665065 having the official title of A Multicenter,
Pivotal Phase 3 Study of Iomab-B Prior to Allogeneic Hematopoietic Cell Transplant Versus Conventional Care in Older Subjects With
Active, Relapsed or Refractory Acute Myeloid Leukemia (AML).

 

	1.47	“Product” means any pharmaceutical product containing, incorporating or comprising
1311- apamistamab (including the product currently known as Iomab-B both dosimetric and therapeutics doses and the product currently
known as Iomab-Act), irrespective of salt form or excipients, in any formulation, mode of administration, presentation or dosage form.

 

	1.48	“Product Trademark” any trademark used exclusively in relation to the Products in the
Territory.

 

	1.49	“Protocol” means sponsor protocol number 8, as such protocol may be amended from time
to time by LICENSOR after discussion at the JSC.

 

	1.50	“Quality Agreement” has the meaning set forth in Section 7.3.

 

	1.51	“Regulatory Approval” means, with respect to the Product in any country or jurisdiction,
any approval (including where required, pricing and reimbursement approvals), registration, license or authorization that is required
by the applicable Regulatory Authority to market and sell the Product in such country or jurisdiction and including any orphan drug designations
or similar rights.

 

	1.52	“Regulatory Authority” means the EMA or any governmental agency or authority responsible
for granting Regulatory Approvals for the Product in any country or jurisdiction in the Territory.

 

	1.53	“Regulatory Filings” means, with respect to the Product, any submission to a Regulatory
Authority of any appropriate regulatory application, including, without limitation, any submission to a regulatory advisory board, any
marketing authorization application, any application for orphan drug designation, and any supplement or amendment thereto. As used herein,
“Regulatory Filings” also includes all correspondence with any Regulatory Authority (and their agents) regarding Product,
including all submissions, meeting minutes, reports and other items submitted to a Regulatory Authority by or under authority of a Party,
its Affiliates or its Sublicensees with respect to a Product, or the Development, Manufacture or Commercialization thereof.

 

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	1.54	“Royalties” has the meaning set out in Section 6.1.3.

 

	1.55	“Services” shall mean the commercial Manufacture of Product to be performed by the
LICENSOR under this Agreement.

 

	1.56	“Specifications” shall mean the specifications for Manufacturing the Product ready
for use, including without limitation all regulatory, manufacturing, quality control and quality assurance procedures, processes, practices,
standards instructions and other attributes for the Product as set forth on Schedule C, as such specifications may be amended by
the Parties due to new data with approval from Regulatory Authority or due to other regulatory requirements, from time to time.

 

	1.57	“Sublicense” means a written agreement appointing a Sublicensee.

 

	1.58	“Sublicensee” means any Third Party to which IMMEDICA has delegated substantially all
of its rights and obligations under this Agreement with respect to any jurisdiction(s) in the Territory, including all of the following:
(i) the exclusive (even as to IMMEDICA) right to purchase Product from LICENSOR (directly or indirectly via IMMEDICA) for sale or use
in such jurisdiction(s), (ii) the exclusive (even as to IMMEDICA) right to seek or hold Regulatory Approval (other than where such Regulatory
Approval is to be held on behalf of IMMEDICA) for the Product in such jurisdiction(s); (iii) the exclusive right (even as to IMMEDICA)
to set the price of the Product in such jurisdiction(s); and (iv) the obligation to Commercialize the Product in such jurisdiction(s).

 

	1.59	“Supply Failure” means a failure by LICENSOR to supply at least [*]% of the Product
ordered by IMMEDICA under this Agreement in two Calendar Quarters in any Calendar Year.

 

	1.60	“Target” means [*].

 

	1.61	“Taxes” has the meaning set forth in Section 6.3.1.

 

	1.62	“Territory” means the current members states of the European Economic Area (together
with any country that becomes a member of the European Economic Area), Algeria, Andorra, Bahrain, Cyprus, Egypt, Iran, Iraq, Israel, Jordan,
Kuwait, Lebanon, Libya. Monaco, Morocco, Oman, Palestine, Qatar, San Marino, Saudi Arabia, Switzerland, Syria, Tunisia, Turkey, the United
Arab Emirates, the United Kingdom, the Vatican City and Yemen. For the avoidance of doubt, if a country ceases to be a member state of
the European Economic Area then, notwithstanding such cessation, such country shall remain part of the Territory

 

	1.63	“Third Party” means any Person other than a Party or an Affiliate of a Party

 

	1.64	“Valid Claim” means either: (a) a claim of an issued and unexpired Patent Right, which
has not been permanently revoked or declared unenforceable or invalid by an unreversed and unappealable or unreversed and unappealed decision
of a court or other appropriate body of competent jurisdiction, or (b) a claim of a pending application for a Patent Right, which claim:
(i) is within [*] from its earliest priority date and was filed and is being prosecuted in good faith and has not been abandoned
or finally disallowed without the possibility of appeal or refiling of such application and (ii) has not been admitted to be invalid or
unenforceable through reissue, reexamination, or disclaimer and which is not subject to an interference claim.

 

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	2.	LICENSE GRANT

 

	2.1.	License Grant.

 

	 	2.1.1.	Licensed Technology. Subject to the terms and conditions of this Agreement, LICENSOR hereby grants
to IMMEDICA an exclusive, royalty-bearing right and license with the right to grant Sublicenses, as provided in Section 2.2, under the
Licensed Technology to Develop and Commercialize the Product in the Field within the Territory. Such license shall not include a license
to Manufacture the Product unless IMMEDICA takes over responsibility for Manufacture in accordance with Section 7.8.5 provided that IMMEDICA
shall be entitled to carry out QP release of and to import the Product. IMMEDICA shall not itself or through or with any Third Party,
conduct or facilitate any research or Development directly related to the Product outside of the Territory without LICENSOR’s prior
written consent.

 

	 	2.1.2.	Trademarks. LICENSOR grants to IMMEDICA an exclusive right and license to use all (i) Product Trademarks
owned or Controlled by LICENSOR or its Affiliates and the Housemarks to the extent that the Housemarks are applied by LICENSOR to the
Product or its packaging, in each case in connection with the Commercialization of the Product in the Field within the Territory. All
marks, whether registered or unregistered, used in connection with the Products must be approved, in writing, by the LICENSOR prior to
use in the Territory which approval will not be unreasonably withheld, conditioned or delayed.

 

	2.2.	Sublicense Rights. IMMEDICA may grant a Sublicense of the rights granted to it by LICENSOR under
this Agreement only with LICENSOR’s prior written consent, and subject to the following requirements:

 

		2.2.1.	Any such Sublicenses shall be subject to and consistent with the terms and conditions of this Agreement,
including, without limitation, with respect to confidentiality, record keeping obligations and audit rights;

 

		2.2.2.	Unless otherwise agreed by the LICENSOR and IMMEDICA, IMMEDICA shall act as the representative of its
Sublicensees for purposes of exercising rights under Section 7 of this Agreement;

 

		2.2.3.	IMMEDICA shall remain responsible for the payment to LICENSOR of all Milestone Payments and Royalties
payable with respect to Net Sales of Products made by such Sublicensees;

 

		2.2.4.	IMMEDICA shall remain liable for the actions and omissions of each Sublicensee; and

 

		2.2.5.	IMMEDICA shall furnish to LICENSOR an accurate and complete copy of each Sublicense agreement with a Third
Party and each amendment thereto prior to execution, provided that any such copy may be redacted to remove any commercially sensitive
or financial terms, or terms which do not relate to the Product.

 

In addition IMMEDICA
may also appoint distributors, wholesalers or appoint any Third Party to provide services including sales, logistics and/or regulatory
services, all of which shall not be considered Sublicensees.

 

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	2.3.	Retained Rights. IMMEDICA acknowledges and agrees that LICENSOR retains (i) the right to make,
have made, and export the Product under the terms of this Agreement, (ii) subject to Section 4.2.2, the right to make, have made
and use the Product for internal research purposes within the Field in the Territory, provided such reservation of rights expressly excludes
(a) the right to conduct Clinical Studies using the Product in the Territory other than those expressly permitted under this Agreement
or as otherwise agreed by the Parties in writing, (b) the right to apply for or to seek Regulatory Approval for the Product in the Territory,
and (c) the right to Commercialize the Product in the Territory, and (iii) the right to make, have made, use and export the Product for
any and all purposes outside of the Territory.

 

	2.4.	Additional Products. If during the term of this Agreement (i) LICENSOR or its Affiliate Develops
or Commercializes either alone or with a Third Party and or (ii) LICENSOR or its Affiliate acquires the right to Develop and Commercialize
in the Territory, any other product comprising an antibody, or another biological therapeutic molecule, conjugated or linked with or otherwise
administered with a radioisotope directed to the Target in the Field and such product obtains Regulatory Approval in any country in an
indication for which the Product has also obtained Regulatory Approval in a country in the Territory or for which an application for Regulatory
Approval has been submitted in a country in the Territory (“Additional Product”) it shall promptly notify IMMEDICA
in writing. IMMEDICA shall have the right within [*] of receiving any such notice to request that LICENSOR shall provide such information
as IMMEDICA shall reasonably request to enable IMMEDICA to assess the Additional Product. IMMEDICA shall have a period of [*], commencing
on its receipt from LICENSOR of the information requested by IMMEDICA, to notify LICENSOR if IMMEDICA wishes to include the Additional
Product under the terms of this Agreement. If IMMEDICA notifies LICENSOR that it does wish to include the Additional Product under the
terms of this Agreement, then from the date of IMMEDICA’s notice, the terms of this Agreement shall apply to such Additional Product
including the provisions of Section 6.1 (other than Section 6.1.1) and the Parties shall agree in good faith any necessary amendments
to the terms of this Agreement. If during the term of this Agreement (i) LICENSOR or its Affiliate Develops or Commercializes either alone
or with a Third Party and or (ii) LICENSOR or its Affiliate acquires the right to Develop and Commercialize in the Territory, any
other product comprising an antibody, or another biological therapeutic molecule, conjugated or linked with or otherwise administered
with a radioisotope directed to the Target in the Field in an indication for which the Product has not obtained Regulatory Approval in
a country in the Territory or for which an application for Regulatory Approval has not been submitted in a country in the Territory (“Other
Product”) LICENSOR shall promptly notify IMMEDICA in writing. If LICENSOR or its Affiliate is proposing to outlicense, sell
or otherwise transfer the right to Develop and or Commercialize such Other Product in the Territory to a Third Party LICENSOR shall notify
IMMEDICA in writing and shall grant IMMEDICA for a period of [*], commencing on the date of IMMEDICA’s receipt of such notice, the
first right to negotiate in good faith the terms of an agreement pursuant to which IMMEDICA would be granted the right to Develop and
Commercialize such Other Product in the Territory. During such [*] period LICENSOR and its Affiliates will not discuss with or grant any
Third Party any right to Develop and or Commercialize the Other Product in the Territory.

 

	2.5.	Territory Exclusivity. LICENSOR shall not and shall ensure that its Affiliates shall not during
the term of this Agreement directly or indirectly (i) grant to a Third Party any rights to Commercialize the Product in the Territory
for use in the Field or (ii) supply Product to a Third Party (other than Sublicensees if requested by IMMEDICA) for any such purpose.

 

	2.6.	No Additional Rights. Nothing in this Agreement shall be construed to confer any rights upon IMMEDICA
by implication, estoppel, or otherwise as to any technology or Intellectual Property Rights of LICENSOR or its Affiliates other than the
Licensed Technology.

 

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	3.	GOVERNANCE

 

	3.1.	Alliance Managers. Within [*] after the Effective Date, each Party shall appoint and notify the
other Party of the identity of a representative having the appropriate qualifications, including a general understanding of pharmaceutical
development and commercialization issues, to act as its alliance manager under this Agreement (the “Alliance Manager”).
The Alliance Managers shall serve as the primary contact points between the Parties for the purpose of providing each Party with information
on the progress and results of the Development and Commercialization of the Product in the Field in the Territory. The Alliance Managers
shall also be primarily responsible for facilitating the flow of information and otherwise promoting communication, coordination and collaboration
between the Parties with respect to the Product and its Manufacture. Each Party may replace its Alliance Manager with a new representative
having the appropriate qualifications at any time upon written notice to the other Party.

 

	3.2.	Joint Steering Committee.

 

		3.2.1.	JSC Formation and Role. Within [*] after the Effective Date, the Parties shall establish a joint
steering committee (the “Joint Steering Committee” or “JSC”) for the overall coordination and oversight
of the Parties’ activities under this Agreement. The role of the JSC shall be to:

 

		(a)	review and discuss the overall strategy for the Development and Commercialization of the Product in the
Territory;

 

		(b)	monitor and discuss the performance and results of the Phase III Clinical Trial and all other Clinical
Studies performed by or on behalf of the LICENSOR pursuant to Section 4.2.1;

 

		(c)	discuss any Clinical Study using the Product in the Territory proposed by either Party including proposed
investigator sponsored studies and any post Regulatory Approval studies aimed at generating real life data with regard to the Product;

 

		(d)	review and discuss the Marketing Plan, including the use of any and all Product Trademarks in connection
with the Products in the Territory, and any proposed amendments or revisions thereto;

 

		(e)	monitor performance of this Agreement as well as progress of the Commercialization activities compared
to the goals defined in the Marketing Plan;

 

		(f)	act as the point of escalation for issues that cannot be resolved otherwise;

 

		(g)	discuss label expansion for additional patient population or indications;

 

		(h)	coordinate the audit of any LICENSOR suppliers and subcontractors relevant to the Product in the Territory,
as further detailed in Section 7.2.2;

 

		(i)	discuss, as applicable, the monitoring of performance under the Manufacturing Agreements, and discuss
any proposal by LICENSOR to enter into new agreements with Third Parties relating to the Manufacture of the Product during the term of
this Agreement;

 

		(j)	discuss any proposal by LICENSOR to enter into a new agreement with a Third Party relating to the Manufacture
of the Products or any proposal to amend the Manufacturing Agreements as further described in Section 12.7;

 

		(k)	establish sub-committees that may have separate member composition from the JSC with mutually acceptable
charters and defined responsibilities to manage key workstreams related to the Parties’ activities under this Agreement, including
but not limited to Development and Commercial sub-committees;

 

		(1)	act as a forum for the Parties to exchange information about the LICENSOR’s Development and Commercialization
activities in respect of the Product outside the Territory and about IMMEDICA’s Commercialization activities in respect of the Product
in the Territory;

 

		(m)	establish a mechanism for dealing with the on-line presence for the Product inside and outside the Territory
in compliance with Applicable Law; and

 

		(n)	perform such other functions as appropriate to further the purposes of this Agreement, as expressly set
forth in this Agreement or as determined by the Parties in writing.

 

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		3.2.2.	Members. The JSC shall be comprised of an equal number of representatives from each Party. Each
Party’ s representatives shall be officers or employees of such Party or its Affiliate having sufficient seniority within the applicable
Party to make decisions arising within the scope of the JSC’s responsibilities. Each Party shall initially appoint three (3) representatives
to the JSC. Each Party may replace its representatives at any time upon written notice to the other Party. Each Party shall appoint one
(1) of its representatives on the JSC to act as the co-chairperson of JSC. The role of the co-chairpersons shall be to preside at the
JSC meetings, but the co-chairpersons shall have no additional powers or rights beyond those held by other JSC representatives. Unless
otherwise agreed by the Parties, the Alliance Managers from both Parties shall be non- voting members of the JSC.

 

		3.2.3.	Meetings. The JSC shall hold meetings on a [*] basis during the term of this Agreement for so long
as the JSC exists, unless the Parties mutually agree to a different frequency for such meetings. Either Party may also call a special
meeting of the JSC in the event such Party reasonably believes that a significant matter must be addressed prior to the next regularly
scheduled meeting and, reasonably in advance of such special meeting, such Party shall provide the JSC with materials adequate to enable
an informed discussion. Reasonably in advance of each JSC meeting, the Alliance Managers (or their designees), on an alternating basis,
shall prepare and circulate an agenda for such meeting; provided that either Party may propose additional topics to be included on such
agenda, either prior to or in the course of such meeting. The JSC may meet in person, by videoconference or by teleconference. No action
taken at a JSC meeting shall be effective unless at least one (1) representative of each Party is present or participating in such meeting.
The Alliance Managers (or their designees), on an alternating basis, shall be responsible for preparing reasonably detailed written minutes
of each JSC meeting and shall send draft meeting minutes to each representative of the JSC for review. The Parties shall agree on meeting
minutes promptly, but in any event no later than [*] following receipt thereof; provided that, if the Parties cannot agree as to the content
of the meeting minutes by such timeframe, such minutes shall be finalized to reflect any areas of disagreement. Each Party may invite,
in addition to its JSC representatives, any number of employees (including employees of Affiliates) and, with the prior written consent
of the other Party, not to be unreasonably withheld, any number of Third Parties, to attend JSC meetings as non-voting participants, provided
that, prior to attending such meetings, such Third Party participants shall be bound by written obligations of confidentiality and non-use
consistent with those contained in this Agreement.

 

		3.2.4.	Decision Making and Escalation. The JSC shall strive to seek consensus in its actions and decision-making
process, and all decisions by the JSC shall be made by unanimous agreement, with each Party’s representatives having collectively
one (1) vote in all decisions. If the Parties’ representatives on the JSC, after reasonable discussion and good faith consideration
of each Party’s opinions, cannot reach agreement on a matter within the JSC’s responsibilities within [*] after the JSC has
met and attempted to agree on such matter (or such other period as the Parties may agree upon in writing), then such disagreement shall
be referred to the Parties’ respective Executive Officers for resolution. Any final decision that the Executive Officers mutually
agree to in writing shall be conclusive and binding on the Parties. If the Executive Officers cannot reach agreement on a matter within
[*] after such matter has been referred to them by the JSC (or such other period as the Executive Officers may agree upon in writing),
then IMMEDICA shall have the tie-breaking vote, and the decision of IMMEDICA’s Executive Officer shall be final and binding on the
Parties, with respect to any matter concerning Regulatory Approval in the Territory, or safety of the Product in the Territory or Commercialization
in the Territory, including regarding the adaptation and localisation of the global marketing and brand strategy for the Product in the
Territory, or, subject to Section 4.3.7, pricing strategy, launch sequencing, reference pricing and importation and distribution matters
in each case with respect to the Product in the Territory, except that LICENSOR shall have the tie-breaking vote, and the decision of
LICENSOR’s Executive Officer shall be final and binding on the Parties, with respect to any matter that will have a material adverse
impact on (a) the global safety profile of the Product, (b) the procurement or maintenance of any Regulatory Approval in any country
or jurisdiction outside of the Territory, (c) changes to the Protocol, and (d) subject to the provisions of Section 4.2, matters
concerning the Development Activities of LICENSOR, including the Clinical Studies carried out by LICENSOR in the Territory in accordance
with the terms of this Agreement and all decisions regarding whether or not LICENSOR will conduct Additional Clinical Studies and Additional
Indication Studies involving the Product.

 

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		3.2.5.	Limitations of JSC Authority. Notwithstanding the foregoing, neither the JSC nor the Party with
final decision-making authority as set forth in Section 3.2.4 shall have the authority to: (a) modify or amend the terms and conditions
of this Agreement; (b) waive or determine either Party’s compliance with this Agreement; (c) decide any issue in a manner that would
conflict with the express terms and conditions of this Agreement; or (d) obligate either Party to violate Applicable Laws or incur any
material liabilities or payment obligations.

 

		3.2.6.	Discontinuation of the JSC. The activities to be performed by the JSC shall solely relate to governance
under this Agreement, and are not intended to be or involve the delivery of services. The JSC shall continue to exist until the Parties
mutually agree to disband the JSC, but in any event the JSC shall be automatically disbanded effective upon the expiration or termination
of this Agreement. Once the JSC is disbanded, it shall have no further obligations under this Agreement and, thereafter, the Alliance
Managers shall be responsible for the exchange of information under this Agreement and the decisions of the Alliance Managers shall be
decisions as between the Parties (but, with final decision-making authority to continue to be in accordance with Section 3.2.4), subject
to the other terms and conditions of this Agreement.

 

	4.	TRANSFER OF LICENSED KNOW-HOW, DEVELOPMENT AND COMMERCIALIZATION

 

	4.1.	Transfer of Licensed Know-How

 

		4.1.1.	Intentionally Omitted.

 

		4.1.2.	Ongoing Transfer. LICENSOR shall, and shall use diligent efforts to cause any contractors to, promptly
transfer to IMMEDICA (or, in the case of contractors, to promptly grant to IMMEDICA a right of reference with respect thereto, if applicable),
from time to time during the term of this Agreement, Licensed Know-How that is necessary or useful for the Development or Commercialization
of the Product in the Field in the Territory as contemplated in this Agreement, including for the purposes of preparing, filing, and maintaining
any Regulatory Approvals in accordance with Section 5.2, to the extent that it has not previously been provided to IMMEDICA hereunder.

 

		4.1.3.	Cooperation. The Parties will cooperate and reasonably agree upon formats and procedures to facilitate
the orderly and efficient exchange of the Licensed Know-How in accordance with this Section 4.1. Without limiting the foregoing,
the LICENSOR shall provide all such items in electronic form to the extent the same exists in electronic form and shall provide copies
and an opportunity to inspect (and copy) original versions for all other materials comprising such Licensed Know-How (including for example,
original patient report forms and other original source data). It is understood that all Licensed Know-How shall be made available to
IMMEDICA in English. Upon request by IMMEDICA, the LICENSOR shall, and shall use diligent efforts to cause any contractors (including
any contract manufacturers) to, reasonably cooperate with and assist IMMEDICA, at LICENSOR’s cost, as may be necessary or desirable
in order to allow IMMEDICA to understand the Licensed Know-How and to utilize the Licensed Know-How for the purposes contemplated in this
Agreement. Notwithstanding the foregoing, if during the term of this Agreement the Parties agree to transfer responsibility for Manufacturing
the Product to IMMEDICA at IMMEDICA’s request, any reasonable costs of LICENSOR associated with the transfer of the Manufacturing
process for the Product to IMMEDICA shall be reimbursed by IMMEDICA, without prejudice to the provisions of Section 7.8.

 

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	4.2.	Development.

 

		4.2.1.	Unless otherwise agreed by the Parties, and except as otherwise provided in this Section 4.2.1 and Section
4.2.3, the LICENSOR shall be solely responsible for the performance of, and all costs relating to, the Development of the Product in the
Territory, including the Phase III Clinical Trial. LICENSOR will use Commercially Reasonable Efforts to continue the on-going Phase III
Clinical Trial in the manner outlined within the Protocol. If any further Clinical Studies are required by a Regulatory Authority in order
to obtain or maintain a Regulatory Approval for the Product (including complying with any paediatric investigation plan or carrying out
any post approval safety or efficacy studies) for active, relapsed or refractory AML in patients aged 55 and older (or any variation to
the foregoing agreed with a Regulatory Authority) in the Territory (“Additional Clinical Studies”), the Parties shall
discuss such required Clinical Studies at the JSC. If the reasonably estimated costs of carrying out such Clinical Studies is less than
[*] the LICENSOR shall carry out such Clinical Studies at its cost as soon as reasonably practicable. If the reasonably estimated costs
of carrying out Additional Clinical Studies is more than [*] the Parties shall discuss in good faith and agree how such Clinical Study
should be carried out and how the costs of such Clinical Study in excess of [*] should be shared between the Parties, provided that LICENSOR
shall not be obligated to perform any such Clinical Study in the absence of agreement between the Parties. Unless otherwise agreed by
the Parties, any such Clinical Study shall be designed to include no more than the minimum number of subjects required by the applicable
Regulatory Authority. Subject to the foregoing, the LICENSOR shall not, and shall not assist, enable or authorize any Affiliate or Third
Party to, undertake any Clinical Study of the Product within the Territory in active, relapsed or refractory AML in patients aged 55 and
older (or any variation to the foregoing agreed with a Regulatory Authority) or any other indication that has obtained Regulatory Approval
in the Territory without the prior written consent of IMMEDICA, which consent shall not be unreasonably withheld, conditioned or delayed.
Any protocol for such proposed Clinical Study within the Territory shall be subject to the prior written approval of IMMEDICA, which approval
shall not be unreasonably withheld, conditioned or delayed.

 

LICENSOR shall
provide the JSC with quarterly reports on the status and progress of all such Development activities. Upon completion of each
Clinical Study (including all Additional Indication Studies) relating to the Product, LICENSOR shall provide the JSC with a final
clinical study report, including all raw data LICENSOR receives or has a right to receive in respect of such Clinical Study.
LICENSOR shall use diligent and reasonable efforts to provide to IMMEDICA all other Product-related data and information requested
by any Regulatory Authority. In addition, the LICENSOR shall, promptly upon filing, provide a complete and accurate copy of all
material Regulatory Filings for the Product submitted to the US Food and Drug Administration for review by IMMEDICA. Subject to the
provision of the data and information by the LICENSOR set out in this Section 4.2.1, and notwithstanding anything to the contrary in
this Section 4.2.1, IMMEDICA shall bear all responsibility and expense for filing all Regulatory Filings in the Territory in
IMMEDICA’s name and obtaining Regulatory Approval for the Product in the Territory. IMMEDICA will undertake such activities at
its sole expense and shall provide to LICENSOR reports regarding IMMEDICA’s progress within [*] following the expiration of
each Calendar Year. In addition, IMMEDICA shall, promptly upon filing, provide a complete and accurate copy of all material
Regulatory Filings (excluding any Regulatory Filings relating to pricing and reimbursement in the Territory) for the Product
submitted to Regulatory Authorities in the Territory for review by LICENSOR. IMMEDICA shall provide to LICENSOR copies of all
pricing and reimbursement approvals obtained by IMMEDICA for the Product in the Territory. If the JSC approves any investigator
sponsored Clinical Studies to be conducted in the Territory IMMEDICA shall be responsible for entering into any agreements with the
applicable investigators for such approved studies. Such agreements will be substantially based on a template agreement that will be
reviewed and approved by the JSC. Upon completion of each such Clinical Study relating to the Product, IMMEDICA shall provide the
JSC with a final clinical study report, including all raw data (in relation to raw data for interventional studies but not raw data
for non- interventional studies) IMMEDICA receives or has a right to receive in respect of such Clinical Study. IMMEDICA shall use
diligent and reasonable efforts to provide to LICENSOR all other Product-related data and information in the possession or control
of IMMEDICA requested by any regulatory authority outside the Territory in relation to the Product.

 

		4.2.2.	Development in new indications by LICENSOR inside the Territory. If the LICENSOR or any Affiliate
or Third Party authorized by the LICENSOR intends to conduct a Clinical Study for the Product in the Territory for an indication in addition
to active, relapsed or refractory AML in patients aged 55 and older (including complying with any paediatric investigation plan) or any
other indication that has, at the relevant date, not been granted Regulatory Approval in the Territory (“Additional Indication
Study”), the LICENSOR shall provide prior written notice thereof, together with a copy of the proposed protocol for such Additional
Indication Study, to IMMEDICA. The LICENSOR shall provide IMMEDICA a reasonable opportunity to comment on any such proposed protocol and
consider in good faith (but without any obligation to incorporate or adopt) any comments provided by IMMEDICA within [*] after delivery
of the proposed protocol to IMMEDICA. Subject to the foregoing provisions LICENSOR shall be entitled to carry out Additional Indication
Studies in the Territory.

 

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		4.2.3.	Development by IMMEDICA. IMMEDICA shall be responsible for carrying out, at IMMEDICA’s sole
cost, all observational studies, registers and health economic studies in relation to the Product in Territory (except any post marketing
studies required to obtain or maintain a Regulatory Approval for the Product which studies shall be the responsibility of the LICENSOR)
and shall keep LICENSOR regularly informed through the JSC with regard to any such studies that it conducts. Upon completion of each such
study, IMMEDICA shall provide the JSC with a final study report, including all raw data (in relation to raw data for interventional studies
but not raw data for non-interventional studies) IMMEDICA receives or obtains, has a right to receive or obtain, in respect of such study.

 

		4.2.4.	Co-Operation. Each Party will keep the other Party reasonably informed through the JSC as to its
regulatory strategy for obtaining regulatory approval of the Product, in the case of the LICENSOR outside the Territory and in the case
of IMMEDICA inside the Territory. The LICENSOR may inform its licensees outside the Territory of IMMEDICA’s Development activities
in respect of the Product in the Territory solely for the purpose of the Development and Commercialization of the Product in such licensees’
respective territory outside the Territory. Each Party shall cooperate as reasonably requested by the other Party in an effort to ensure
that the Parties’ Development activities, as they relate to obtaining regulatory approval of the Product are coordinated worldwide,
provided however that this shall not be interpreted or construed as limiting IMMEDICA’s and the LICENSOR’s rights and obligations
under this Agreement.

 

		4.2.5.	The Parties shall each ensure that they comply with all Applicable Laws with respect to the performance
of their obligations hereunder and in the performance of all Clinical Studies relating to the Product.

 

		4.2.6.	Prohibition on Development of Competing Products. IMMEDICA shall not, during the term of this Agreement,
Develop or Commercialize any pharmaceutical product for conditioning treatment, inside or outside the Territory, itself or through or
with a Third-Party, that competes with an indication approved under a Regulatory Approval for the Product, except upon the prior written
consent of the LICENSOR.

 

	4.3.	Commercialization. IMMEDICA shall be solely responsible for the Commercialization of the Product
in the Territory. IMMEDICA will undertake such activities at its sole expense.

 

		4.3.1.	Marketing Plan. No later than [*] before the expected launch of the Product in the Territory IMMEDICA
will prepare an initial marketing plan for the Product (“Marketing Plan”) according to IMMEDICA’s marketing planning
process, but will include at a minimum, medical education and communication, brand strategy, brand positioning, key messages, public relations,
access, and reimbursement, sales and distribution strategies. The LICENSOR will notify IMMEDICA of LICENSOR’s global marketing strategy
for the Product on an annual basis. Such strategy shall include medical education and communication, brand strategy, brand positioning,
key messages, public relations, access, and reimbursement, sales and distribution strategies.

 

		4.3.2.	Review and Comment on Marketing Plan. IMMEDICA will submit the final draft of the initial and any
materially updated Marketing Plan to LICENSOR, via the JSC, for review and comment. LICENSOR will provide comments on such draft to the
JSC within [*] after receipt. The JSC shall meet to review the Marketing Plan and any comments provided by LICENSOR, and IMMEDICA will
reasonably consider such comments, prior to finalization and implementation of the Marketing Plan. Notwithstanding anything herein to
the contrary, if LICENSOR notifies IMMEDICA that the Marketing Plan conflicts with LICENSOR’s global commercialization strategy,
IMMEDICA shall not finalize and implement the Marketing Plan until such conflict is resolved to the satisfaction of both Parties.

 

		4.3.3.	Diligence Obligations. IMMEDICA shall itself, or through its Affiliates or Sublicensees, use Commercially
Reasonable Efforts to Commercialize the Product in the Territory, including using Commercially Reasonable Efforts to perform the activities
set forth under each Marketing Plan. All efforts of IMMEDICA’s Affiliates and Sublicensees will be considered efforts of IMMEDICA
for the purpose of determining IMMEDICA’s compliance with its obligations under this Section 4.3.3.

 

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		4.3.4.	Shipment and Policing of Product Outside the Territory. IMMEDICA may not deliver or tender (or
cause to be delivered or tendered) any Product outside of the Territory. If IMMEDICA becomes aware that any customer of the Product in
the Territory (including a distributor, wholesaler or health group) is reselling or distributing any quantities of the Product acquired
from IMMEDICA outside the Territory, then IMMEDICA shall notify LICENSOR in writing and take reasonable steps to cause such customer to
cease reselling or distributing the Product outside the Territory. If IMMEDICA receives any order from a prospective purchaser located
outside the Territory, IMMEDICA shall not accept any such orders and shall promptly inform LICENSOR of such order(s).

 

		4.3.5.	Shipment and Policing of Product Inside the Territory. Except with respect to the delivery of Product
for use in connection with Clinical Studies in the Territory and sales of the Product by LICENSOR to IMMEDICA under this Agreement, the
LICENSOR may not deliver or tender (or cause to be delivered or tendered) any Product inside the Territory. If the LICENSOR becomes aware
that any customer of the Product outside of the Territory (including a distributor, wholesaler or health group) is reselling or distributing
any quantities of the Product inside the Territory, then the LICENSOR shall notify IMMEDICA in writing and take reasonable steps to cause
such customer to cease reselling or distributing the Product in the Territory. If the LICENSOR receives any order from a prospective purchaser
located inside the Territory, the LICENSOR shall not accept any such orders and shall provide prompt written notice of such order(s) to
IMMEDICA.

 

		4.3.6.	Labeling and Artwork. Cutter guides (technical drawings of the Artwork mock-ups) will be provided
by LICENSOR to IMMEDICA. IMMEDICA shall be responsible for updating the cutter guides and the creation of printer ready labeling mock-ups
in the Territory according to local regulations and guidelines. In the event that IMMEDICA proposes changes to the labeling or packaging
of the Product, it shall provide LICENSOR with justification for the proposed change, revised mock-ups for printing and clear timelines
for the implementation of such updates The actual cost of implementing such change will be at IMMEDICA’s sole cost and expense,
including any materials made obsolete by IMMEDICA’s changes to the artwork, unless such change was requested by the LICENSOR, in
which case such cost and expense shall be at the LICENSOR’s sole cost and expense. All labeling, artwork, packaging and proposed
changes thereto shall at all times comply with Applicable Laws.

 

		4.3.7.	Pricing and Reimbursement. IMMEDICA shall be solely responsible for all pricing and reimbursement
matters relating to the Product in the Territory including all related discussions with Regulatory Authorities including relevant pricing
and reimbursement bodies; provided that if IMMEDICA supplies the Product in the Territory at a price that would cause the LICENSOR to
incur a loss on its fully burdened cost of Manufacture of the Product as notified to IMMEDICA prior to the date of any such supply, IMMEDICA
shall reimburse LICENSOR for any such shortfall. Notwithstanding the foregoing sentence, if approved by the JSC, IMMEDICA shall be entitled
to provide Product at no charge for the purpose of any investigator sponsored Clinical Studies conducted in the Territory with the JSC’s
prior approval, or as donations or the like or as “treatment IND sales”, “named patient sales”, “compassionate
use sales”, or pursuant to any expanded access programs, or any equivalent; provided that the quantities of Product provided at
no charge do not exceed the quantities approved by the JSC for such purpose. IMMEDICA will reimburse LICENSOR for any Product supplied
that exceeds quantities approved by the JSC for such purpose. Each Party shall promptly provide to the other Party a copy of any cost
effectiveness model and/or value dossier developed by such Party relating to a Product for the other Party’s review.

 

		4.3.8.	Co-Operation. Each Party will keep the other Party reasonably informed through the JSC as to its
Development and Commercialization activities in respect of the Product, in the case of the LICENSOR outside the Territory and in the case
of IMMEDICA inside the Territory. The LICENSOR may inform its licensees outside the Territory of IMMEDICA’s Commercialization activities
in respect of the Product in the Territory solely for the purpose of the Development and Commercialization of the Product in such licensees’
respective territory outside the Territory. The will keep IMMEDICA informed of its own and such licensee’s Development and Commercialization
activities in respect of the Product solely for the purpose of IMMEDICA’s Commercialization of the Product in the Territory. Each
Party shall cooperate as reasonably requested by the other Party in an effort to ensure that the Development and Commercialization of
the Product is coordinated worldwide, provided however that this shall not be interpreted or construed as limiting IMMEDICA’s and
the LICENSOR’s rights and obligations under this Agreement. The Parties will cooperate in good faith with regard to agreeing on
matters that relate to the Product inside and outside the Territory such as attendance at international conferences. LICENSOR shall ensure
that LICENSOR’s, its Sublicensees’ and/or Affiliates’ engagement with healthcare professionals in relation to the Product
is in accordance with the Applicable Law in the country in the Territory where such healthcare professional is normally located and IMMEDICA
shall ensure that IMMEDICA’s, its Sublicensees’ and/or Affiliates’ engagement with healthcare professionals in relation
to the Product is in accordance with the Applicable Law in the country outside the Territory where such healthcare professional is normally
located. Each Party shall keep the other reasonably informed with regard to such matters provided that this obligation shall not require
the Parties to keep each other informed in relation to incidental or immaterial interactions with healthcare professionals at international
conferences.

 

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	5.	REGULATORY MATTERS

 

	5.1.	Marketing Authorization Holder. Subject to IMMEDICA’s obligations upon termination pursuant
to Section 15.6, IMMEDICA shall be the holder and owner of all Regulatory Approvals in the Territory. Promptly and in any event within
[*] of the Effective Date, LICENSOR shall assign the Orphan Drug Designation for the Product in the Territory to IMMEDICA.

 

	5.2.	Maintenance of Marketing Authorizations. With respect to the Product, IMMEDICA shall have the right,
at its sole discretion and cost and expense, to prepare, file and maintain such Regulatory Approvals in the Territory throughout the term
of this Agreement including obtaining any variations or renewals thereof. Without limiting the foregoing, IMMEDICA shall be responsible
for filing and shall use its Commercially Reasonable Efforts to file the marketing authorization application for the Product with the
EMA. LICENSOR shall provide IMMEDICA with all information in the possession or control of LICENSOR or its Affiliates or licensees or assignees
of the Product outside the Territory reasonably required by IMMEDICA to prepare, file and maintain any such application and any Regulatory
Approval including any filings for Regulatory Approval for the Product made by or on behalf of LICENSOR, its Affiliates or its licensees
or assignees outside the Territory. LICENSOR shall also, at no cost to IMMEDICA (as long as such costs are reasonable), make reasonably
available its personnel and subject matter experts with the knowledge of the Development of the Product to consult with IMMEDICA and to
provide reasonable assistance in a timely manner to IMMEDICA in connection with any of the foregoing, including but not limited to supporting
IMMEDICA’s preparation of the EU marketing authorization application for the Product (through the provision of documentation for
and attendance at pre-submission meetings with EMA as relevant) and supporting Il’v1MEDICA with respect to the EMA assessment of
the application and any questions raised by the EMA including attending meetings with the EMA to answer any such questions.

 

	5.3.	Interaction with Regulatory Authorities. After the Effective Date, each Party shall provide to
the other Party a copy of any material correspondence or materials that it receives from or submits to a Regulatory Authority or any material
decision made by a Regulatory Authority regarding, in each case, the Product, in respect of IMMEDICA, in the Territory and, in respect
of LICENSOR, outside of the Territory. LICENSOR shall use reasonable efforts to cause that its licensees or assignees in relation to the
Product outside the Territory to provide such information as is required by Section 5.2 above and this Section 5.3 to LICENSOR to enable
LICENSOR to comply with its obligations. If such correspondence received by a Party is not in English, then such copy will include a summary
in English of all material matters addressed thereby. IMMEDICA shall provide reasonable advance written notice to LICENSOR of all material
meetings, conferences, or calls with Regulatory Authorities concerning the Product (excluding meetings, conferences, or calls with Regulatory
Authorities relating to pricing and reimbursement of the Product), and LICENSOR shall be permitted to have appropriate representatives
attend all such meetings, conferences, or calls to the extent permitted by Applicable Law. IMMEDICA shall provide LICENSOR with copies
of any materials relating to any material regulatory matter relating to the Product (excluding materials relating to pricing and reimbursement)
and, when reasonably practicable, shall provide copies of any documents to be presented to any Regulatory Authority in respect of such
matters prior to their presentation thereto. In addition, during the term of the Agreement and with respect to all Product supplied and
purchased under this Agreement, after the termination of this Agreement, each Party shall promptly (and in any case within [*]) notify
the other Party of any information it receives regarding any threatened or pending action, inspection or communication by or from a concerned
Regulatory Authority which may affect the safety or efficacy claims of the Product or the continued marketing of the Product. Upon receipt
of such information, the Parties shall consult with each other in an effort to arrive at a mutually acceptable procedure for taking appropriate
action. The materials to be provided under this Section 5.3 with respect to material interactions with any Regulatory Authority will be
forwarded to the other Party promptly after receipt.

 

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	5.4.	Right of Reference. Subject to the terms and conditions set forth in this Agreement, (i) LICENSOR
hereby grants to IMMEDICA a fully paid, exclusive right and license to reference any Regulatory Approvals Controlled by LICENSOR or its
Affiliates for the Product outside the Territory for the purpose of obtaining Regulatory Approval of the Product in one or more countries
in the Territory, and (ii) IMMEDICA hereby grants to LICENSOR, its Affiliates and its licensees a fully paid, exclusive right and
license to reference any Regulatory Approvals Controlled by IMMEDICA or its Affiliates or Sublicensees for Product inside the Territory
for the purpose of obtaining Regulatory Approval of the Product in one or more countries outside the Territory; provided that if the exercise
of the right of reference under this Section 5.4(i) triggers any inspection or audit of LICENSOR (or its Affiliates or licensees
outside the Territory) then IMMEDICA will reimburse LICENSOR (or its Affiliates or licensees outside the Territory) for the costs incurred
by LICENSOR (or its Affiliates or licensees outside the Territory) in respect of such inspection or audit; and provided further that if
the exercise of the right of reference under this Section 5.4(ii) triggers any inspection or audit of IMMEDICA then LICENSOR will
reimburse IMMEDICA for the costs incurred by IMMEDICA in respect of such inspection or audit.

 

	5.5.	Pharmacovigilance. The LICENSOR will be responsible for managing the global safety database for
the Product. Within [*] after the Effective Date, the Parties shall enter into a pharmacovigilance agreement pursuant to which the Parties
will mutually exchange adverse events or other safety data within and outside of the Territory as required for each Party to fulfill the
relevant requirements in accordance with Applicable Law. IMMEDICA may maintain its own safety database for the Product for safety data
collection, evaluation and reporting as well as for purposes of safety surveillance, risk management as required in the Territory. The
LICENSOR shall provide information on individual case safety reports from the global safety database for the Product to IMMEDICA to be
further specified in the pharmacovigilance agreement. The Parties shall mutually maintain a procedure for reconciliation of safety data
between the safety databases of the Parties. As between the Parties: (a) IMMEDICA shall be responsible for the pharmacovigilance
surveillance, risk management and timely reporting of adverse drug reactions/experiences, and safety data relating to the Product to the
appropriate Regulatory Authorities in the Territory in accordance Applicable Law in the Territory; and (b) LICENSOR or its licensee(s)
shall be responsible for the pharmacovigilance surveillance, risk management and timely reporting of adverse drug reactions/experiences,
and safety data relating to the Product to the appropriate Regulatory Authorities outside the Territory, in each case in accordance with
Applicable Laws. The Parties shall cooperate with each other with respect to their respective pharmacovigilance responsibilities and any
safety related changes to the Product label or other additional pharmacovigilance or risk minimization activities.

 

	5.6.	Promotional Materials. IMMEDICA shall be responsible for developing the promotional materials for
use in Commercializing the Product in the Territory in accordance with Applicable Law and shall ensure that such materials are consistent
with LICENSOR’s global marketing strategy for the Product as notified to IMMEDICA in accordance with Section 4.3.1. If IMMEDICA
proposes to use promotional materials that deviate significantly from any such global marketing strategy such materials will be submitted
to LICENSOR for review and approval prior to use. IMMEDICA shall own all rights in any promotional materials it creates. IMMEDICA shall
deliver copies of all promotional materials it creates for the Product to the LICENSOR prior to distribution or use.

 

	5.7.	Medical Inquiries. Following grant of the first Regulatory Approval for the Product in the Territory
IMMEDICA will be responsible for handling all medical questions or inquiries in respect of the Product in the Territory. The LICENSOR
shall promptly forward any and all medical questions or inquiries which it receives in respect of the Product in the Territory to IMMEDICA
in accordance with Applicable Laws. The LICENSOR shall be responsible for handling all medical questions or inquries in respect of the
Product outside of the Territory. IMMEDICA shall promptly forward any and all medical questions or inquiries which it receives in respect
of the Product outside the Territory to the LICENSOR in accordance with Applicable Laws. The Parties shall cooperate and establish the
procedures reasonably necessary (such as periodic meetings via teleconference or videoconference) to ensure the consistency and correctness
of the medical information provided by the Parties.

 

	6.	PAYMENT TERMS

 

	6.1.	Payment Terms .

 

		6.1.1.	Upfront Payment. IMMEDICA shall pay to LICENSOR an upfront payment as set forth in Schedule
B within [*] of the Effective Date, subject to the receipt of the applicable invoice from the LICENSOR.

 

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		6.1.2.	Milestone Payments. IMMEDICA shall notify LICENSOR [*] upon achievement of each Milestone. IMMEDICA
shall pay to LICENSOR each applicable milestone payment set forth in Schedule B (each, a “Milestone Payment”) within
[*] after the achievement of such Milestone is notified to LICENSOR, subject to the receipt of the applicable invoice from the LICENSOR.

 

		6.1.3.	Royalty Payments. On a country-by-country basis, from the date of First Commercial Sale in such
country in the Territory, and for the remainder of the term of this Agreement, IMMEDICA shall pay to LICENSOR the royalties set forth
in Schedule B (collectively, “Royalties”) within [*] following the expiration of each Calendar Quarter.
All payments shall be accompanied by a report that includes for the applicable Calendar Quarter the following information on a country-by-country
basis: (a) gross sales of Product in United States Dollars (including any foreign exchange rates employed); (b) Net Sales of Product (including
any foreign exchange rates employed); (c) Deductions taken from gross sales (by category as set forth in the definition of Net Sales)
to arrive at the Net Sales calculation (including any foreign exchange rates employed); and (d) the Royalties payable to LICENSOR
in United States Dollars and in Euros (€) (including any foreign exchange rates employed).

 

		6.1.4.	Other Payments. IMMEDICA shall pay to LICENSOR any other amounts due under this Agreement within
[*] following receipt of invoice, subject to the receipt of the applicable invoice from the LICENSOR.

 

		6.1.5.	Late Payments. Any late payments shall bear interest, to the extent permitted by law, at [*] above
the Euribor three months rate of interest on the date payment is due.

 

		6.1.6.	Payments under Existing Agreements. LICENSOR shall be responsible for making all payments of any
sums due under the Existing Agreements to the applicable counterparty to the agreement in respect of the activities conducted under this
Agreement including any milestone or royalty payments.

 

	6.2.	Payment Method.

 

		6.2.1.	For the purpose of calculating any sales milestone payment threshold expressed in Euros, any Net Sales
that are received by IMMEDICA in currencies other than Euros shall be converted into Euros at the average (mean) monthly closing prevailing
foreign exchange rate published by the European Central Bank (or any other qualified source that is acceptable to both Parties) during
the applicable Calendar Quarter in which such amounts were booked, or for periods less than a Calendar Quarter, the average (mean) prevailing
foreign exchange rate published by the European Central Bank during such period.

 

		6.2.2.	All payments from IMMEDICA to LICENSOR shall be made in US Dollars. For the purpose of calculating Royalties
and Milestone Payments not expressed in US Dollars, Net Sales and Milestone Payments shall be converted into US Dollars at the average
(mean) daily closing prevailing foreign exchange rate published by the European Central Bank (or any other qualified source that is acceptable
to both Parties) (a) in the case of Royalties, during the applicable Calendar Quarter in which such Royalty is payable; and (b) in the
case of Milestone Payments, on the date the Milestone triggering such Milestone Payment is achieved. Each such payment shall be made by
wire transfer to the credit of such bank account as may be designated by LICENSOR in writing to IMMEDICA. Any payment which falls due
on a date which is not a Business Day may be made on the next succeeding Business Day.

 

	6.3.	Taxes.

 

		6.3.1.	It is understood and agreed between the Parties that any amounts payable by IMMEDICA to LICENSOR hereunder
are exclusive of any and all applicable sales, use, VAT, GST, excise, property, and other taxes, levies, duties or fees (collectively,
“Taxes”). IMMEDICA shall be responsible for billing and collection from its customers and remitting to the appropriate
taxing authority any and all Taxes which it is required to collect or remit. Each Party will be responsible for their own income and property
taxes.

 

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		6.3.2.	If IMMEDICA is required to make a payment to LICENSOR subject to a deduction of tax or withholding tax
(a “Withholding Tax Requirement”), then to the extent such amounts are deducted, withheld and paid by or on behalf
of IMMEDICA to the appropriate taxing authority, such amounts shall be treated for all purposes of this Agreement as having been paid
to the LICENSOR. IMMEDICA shall provide LICENSOR with official receipts issued by the appropriate governmental agency to IMMEDICA.

 

		6.3.3.	The Parties agree to cooperate and produce on a timely basis any tax forms or reports and any other documentation
required to prove treaty eligibility (which may vary depending on the applicable country), reasonably requested by the other Party in
connection with any payment made by IMMEDICA to LICENSOR under this Agreement.

 

	7.	MANUFACTURE AND SUPPLY

 

	7.1.	Purchase and Sale of Product. During the term of this Agreement and in accordance with the terms
and conditions set forth herein, (a) the LICENSOR shall have Product Manufactured and sell and deliver to IMMEDICA Product packaged and
labeled and ready for use; and (b) IMMEDICA shall order, purchase, and take delivery of [*] exclusively from the LICENSOR. For the avoidance
of doubt, other than the serialization of the Product (which as at the Effective Date the Parties agree is not required), the foregoing
does not operate to grant any license to IMMEDICA to Manufacture or have Manufactured the Product.

 

	7.2.	Manufacturing Standards and Practices.

 

		7.2.1.	The LICENSOR shall have Product Manufactured for IMMEDICA at the Facility in accordance with the Specifications,
GMP, all Applicable Laws, the Quality Agreement and the terms and conditions of this Agreement. LICENSOR shall consult with IMMEDICA prior
to any change to the Facility that would impact the Regulatory Approval for the Product in the Territory (including any change that would
require a variation of the Regulatory Approval). LICENSOR shall provide notice and rationale of any such change to IMMEDICA as promptly
as practicable to allow IMMEDICA to file and seek approval of any variation or amendment to a Regulatory Approval before such change is
implemented. Justification for the proposed changes as well as any updated sections to the Regulatory Dossier Module 3 (CMC) documentation
required to support such variation will be provided to IMMEDICA by LICENSOR at LICENSOR’s expense. The Specifications will not be
amended or modified unless agreed by both Parties in writing. If any Regulatory Authority requires a change to the Specifications or if
any such change is required by a change in Applicable Law the Parties will discuss and agree how to implement such change. LICENSOR shall,
and shall use reasonable efforts to cause its Third Party suppliers to, support IMMEDICA in gathering any information and data (including
through carrying out stability studies) required for IMMEDICA to fullfil its obligation to submit such regulatory variations, or fullfil
obligations associated with such variations (including ‘Post approval commitments’). IMMEDICA shall pay the filing fee associated
with any application by IMMEDICA for a variation to a Regulatory Approval for the Product in the Territory. Any other costs, fees or expenses
incurred as a result of having to file an application for a variation as a result of such a change in the Facility or change to the Specifications
or a requirement of a Regulatory Authority shall be borne by (i) IMMEDICA if such variation is required as a result of a request from
IMMEDICA, a change or requirement of a Regulatory Authority in the Territory or a change in Applicable Laws in the Territory and (ii)
in all other cases shall be borne by LICENSOR. For clarity, except as otherwise required to comply with Applicable Laws, until such time
as a variation is approved by the applicable Regulatory Authority LICENSOR shall continue to supply the Product to IMMEDICA in accordance
with the unamended Specification and Regulatory Approval.

 

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		7.2.2.	IMMEDICA shall have the right, at its sole expense, to audit the LICENSOR for compliance with Applicable
Laws, GMP and the terms of the Quality Agreement on reasonable prior written notice during normal business hours and not more than [*]
in each Calendar Year. In addition, and subject to reasonable confidentiality obligations, IMMEDICA shall have the right, at its sole
expense, to join with LICENSOR during its annual audit of LICENSOR’s suppliers and subcontractors for compliance with Applicable
Laws, GMP and the terms of the Quality Agreement and any for-cause audits and audits required by Applicable Law. The LICENSOR shall co-operate
in good faith in scheduling, attending at and assisting in all IMMEDICA audits. To assist in such scheduling arrangements, the LICENSOR
shall notify IMMEDICA at least [*] in advance (or, in the case of for-cause audits, as soon as reasonably practicable) in the event that
the LICENSOR intends to conduct any audit at any suppliers or subcontractors and, if so desired by IMMEDICA, the LICENSOR shall use its
reasonable efforts to allow IMMEDICA to attend and fully participate in such audit. In the event that IMMEDICA audits a LICENSOR supplier
or subcontractor, the LICENSOR has the right to be on site during the audit and act as an observer between IMMEDICA and such supplier
or subcontractor. The LICENSOR may charge its reasonable costs and expenses for such attendance if such audit takes place more than [*]
per year, unless IMMEDICA identifies a material defect in the LICENSOR’s or any subcontractor’s or supplier’s performance
of its obligations under this Agreement, justifying an audit. If IMMEDICA or its representatives notify the LICENSOR of any defects in
the LICENSOR’s or any subcontractor’s or supplier’s performance of its obligations under this Agreement, including non-compliance
with any Applicable Laws, the LICENSOR shall correct, or cause its suppliers or subcontractors to correct, the defects as soon as practicable
at the LICENSOR’s expense and shall provide such evidence as IMMEDICA may reasonably request that such defects have been remedied.

 

		7.2.3.	The LICENSOR shall provide IMMEDICA with certificates of analysis for all Product supplied hereunder based
upon a reference standard established by the LICENSOR and reasonably acceptable to IMMEDICA.

 

		7.2.4.	Upon the reasonable request of IMMEDICA following the release and shipment of any Product supplied under
this Agreement, the LICENSOR shall provide IMMEDICA with such information, including analytical and manufacturing documentation, batch
records for Product and stability data, in each case requested by IMMEDICA regarding quality control of such Product. Without limiting
the foregoing obligations, IMMEDICA acknowledges and agrees that IMMEDICA is responsible for the final disposition and release of Product
in the Territory.

 

		7.2.5.	All information disclosed or obtained pursuant to this Section 7.2 shall constitute Confidential Information
of the LICENSOR.

 

	7.3.	Quality Assurance. Within [*] of the Effective Date, the Parties shall enter into a quality assurance
agreement for the Product (the “Quality Agreement”). The Quality Agreement shall address the standard quality terms
of supply and relevant other terms, including, terms relating to specifications, product warranties, quality testing, storage, shipment,
labelling, quality controls and regulatory matters.

 

	7.4.	Materials. Unless otherwise agreed to in writing by the Parties, the LICENSOR shall be responsible
at its expense for obtaining all Materials in reasonable quantities consistent with the LICENSOR’s supply obligations under the
then-current purchase order, on timelines that enable the LICENSOR to meet its delivery and supply obligations under all applicable purchase
orders and this Agreement, taking into account the forecast demand for Product as reflected in the most recent Forecast.

 

	7.5.	Handling and Storage. The LICENSOR shall and shall cause its suppliers and subcontractors to handle
and store the Product and the Materials for the Product pursuant to GMP and otherwise in a commercially reasonable manner and in accordance
with, as applicable (a) the Specifications, (b) Applicable Laws, including GMP, and (c) the terms of the Quality Agreement. LICENSOR shall
and shall cause its suppliers and subcontractors to comply with such other practices and procedures mutually agreed upon in writing between
the LICENSOR by IMMEDICA.

 

	7.6.	Packaging and Labeling. As between the Parties, LICENSOR shall be solely responsible for packaging
and labeling the Product for sale and distribution in the Territory. IMMEDICA shall be responsible for providing to LICENSOR artwork for
the packaging to be applied to the Product by LICENSOR.

 

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	7.7.	Forecasts and Orders.

 

		7.7.1.	Not less than [*] prior to the first day of each Calendar Quarter (commencing with the first Calendar
Quarter in which IMMEDICA orders Product from the LICENSOR hereunder), IMMEDICA shall prepare and provide the LICENSOR with a written
forecast of its good faith estimated requirements for Product for each of [*] (each a “Forecast”). IMMEDICA shall not
increase or decrease the quantity estimated for [*] of each Forecast from the quantity estimated for such periods in the previous Forecast.
The quantities estimated for all subsequent Calendar Quarters of each Forecast shall be non-binding, and for planning purposes only. By
way of example, if IMMEDICA issues a forecast on [*], [*] shall be binding on the Parties and the forecasts for [*] shall not be binding
on the Parties. In addition, IMMEDICA will provide on a country-by-country basis its good faith estimated number of patients to be treated
in the Forecast for the purposes of LICENSOR providing dosimetric doses of the Product. LICENSOR will supply dosimetric doses based on
such Forecast of the Product in a manner it reasonably believes most efficient, provided however, it will ensure that dosimetric doses
are supplied to all identified patients in accordance with the terms of this Agreement. Therapeutic doses of the Product will be supplied
on a per patient basis pursuant to the terms of this Agreement.

 

		7.7.2.	The LICENSOR shall be required to supply the quantity of Product ordered by IMMEDICA under this Section
7.7 in any Calendar Quarter up to the quantity forecasted for the [*] of the most recent Forecast in a manner that is reasonably practical
given the nature of the Product. If IMMEDICA’s orders in any Calendar Quarter exceed the quantity forecasted for the [*] of the
most recent Forecast, the LICENSOR shall use commercially reasonable efforts to supply such excess. The LICENSOR shall use commercially
reasonable efforts to meet IMMEDICA’s delivery requirements specified in accordance with Section 7.7.3. In the event of a shortfall,
the LICENSOR shall promptly inform IMMEDICA and use Commercially Reasonable Efforts to apportion Product among IMMEDICA, the LICENSOR,
and its other customers on a [*] according to their respective forecasts for the relevant period provided always that such forecasts were
proposed in good faith. The LICENSOR shall not give priority of supply to its requirements or its licensees requirements for the Product
outside the Territory.

 

		7.7.3.	IMMEDICA shall make all purchases under this Section 7.7 by submitting firm purchase orders to the LICENSOR.
On a [*] basis, IMMEDICA shall submit such purchase order in writing in a form reasonably acceptable to the LICENSOR, and shall specify
the quantity of Product ordered, the place of delivery and the required delivery date therefor, which shall not be less than [*] from
after the date of such purchase order. On a continual basis, IMMEDICA shall inform LICENSOR as soon as practical of identified potential
patient and when a dosimetric dose of Product has been administered. Except as otherwise expressly provided in this Agreement, the LICENSOR
shall be paid for its supply of the Product via the royalty paid by IMMEDICA under Section 6.1.3.

 

		7.7.4.	During the Term of this Agreement, to the extent that IMMEDICA orders a quantity of Product that is
                                                                                                       less than the quantity specified in the binding [*] of the Forecasts provided under Section 7.7.1, IMMEDICA shall refund
                                                                                                       LICENSOR’s wasted out-of pocket costs of buying iodine 131 and/or reserving non- cancellable manufacturing slots to
                                                                                                       manufacture Product that was not subsequently ordered, subject to the provision by LICENSOR of appropoirate evidence of such costs
                                                                                                       and to the extent that such iodine 131 or such manufacturing slots cannot be reused or cancelled by LICENSOR.

 

	7.8.	Delivery and Acceptance.

 

		7.8.1.	All Product supplied under this Agreement shall be shipped [*] (Incoterms 2020) to the destination port
designated by IMMEDICA in its purchase order, which shall be in the European Union. Any change in the location of delivery shall require
the consent of both Parties, such consent not to be unreasonably withheld or delayed. Title to the Product purchased by IMMEDICA hereunder
shall pass to IMMEDICA upon delivery at the destination port. IMMEDICA shall be responsible for import duties, import clearance and acting
as the importer for such Product.

 

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		7.8.2.	The LICENSOR shall insure the Products during transit. The LICENSOR and IMMEDICA shall cooperate to ensure
all import clearances and other taxes, duties and formalities are paid and in place prior to delivery.

 

		7.8.3.	During the term of this Agreement, the LICENSOR agrees and undertakes to maintain a minimum stock of the
Materials required to Manufacture the Product with the exception of 131-1 radioisotope equal to the amount required to Manufacture or
have Manufactured [*] supply of Product for the Territory in accordance with the most recent Forecast.

 

		7.8.4.	If
the LICENSOR, at any time during the Manufacturing process, becomes aware that for any reason the LICENSOR will not be able to deliver
to IMMEDICA the agreed quantity of conforming Product on the agreed delivery date in accordance with the terms of any purchase order
or this Agreement (a “Delay”), or any Delay is likely to occur (an “Anticipated Delay”), then the
LICENSOR shall use its reasonable efforts to minimize, cure or overcome such Delay and/or Anticipated Delay as soon as reasonably possible.
Promptly upon the LICENSOR first becoming aware of any Delay or Anticipated Delay, it shall notify the JSC and the IMMEDICA Alliance
Manager of such fact in writing. The JSC shall convene a meeting as soon as reasonably possible following such notice, to consider what
steps should be taken to avoid or mitigate such Delay and/or Anticipated Delay and to develop a plan to avoid any Delay occurring, in
the event of an Anticipated Delay, to mitigate the effects of any Delay and how to prevent any Delay and/or Anticipated Delay from occurring
in the future, including the appointment of a Third Party Manufacturer or the allocation of more capacity to the Manufacture of Products
for IMMEDICA. In the event that a Third Party Manufacturer is appointed, the costs of the associated technology transfer shall be borne
solely by the LIC: NSOR and shall be subject to the agreement of a high-level plan for the full and complete transfer of the relevant
manufacturing Know- How and technology to such Third Party Manufacturer. In the event of an issue at the Facility, or a supply shortage
of the Product affecting IMMEDICA and/or the LICENSOR, its Affiliates and other licensees and Sublicensees, then the LICENSOR shall ensure
that IMMEDICA receives a fair and reasonable pro rata share of any Product based on the quantities of Product included in purchase
orders placed in the last Calendar Year before such Facility issue or supply shortage occurred.

 

		7.8.5.	In the event of a Supply Failure or a Bankruptcy Event in relation to the LICENSOR all licenses granted
under this Agreement shall automatically include a right for IMMEDICA to Manufacture, or have Manufactured, the Product, including both
the drug product and drug substance, and IMMEDICA is hereby authorized to contract with any party to the Manufacturing Agreements or any
other Third Parties for the purposes of such Manufacture, provided always that this shall be without prejudice to the LICENSOR’s
right to receive royalties under Section 6.1.3. In the event that IMMEDICA undertakes Manufacture of the Product under this Section
7.8.5 (either itself or through an Affiliate or a Third Party) the LICENSOR will on request from IMMEDICA and at the LICENSOR’S
own cost promptly conduct a technology transfer to IMMEDICA, its AFFILIATE or appointed Third Party supplier (as directed by IMMEDICA)
to enable IMMEDICA to Manufacture or have Manufactured the Product. In addition if any Supply Failure results from a breach of any agreement
between LICENSOR and a Third Party contract manufacturer of the Product IMMEDICA shall have the right to cure such breach on behalf of
LICENSOR and LICENSOR shall reimburse IMMEDICA for all costs and, expenses incurred and compensation paid by IMMEDICA in connection with
curing such breach.

 

	7.9.	Defective Product.

 

		7.9.1.	If a shipment of Product or any portion thereof is not in conformance with the Specifications, Applicable
Law, GMP, the terms of the Quality Agreement or does not have specific activity required in accordance with the calculated therapeutic
dose level when received by IMMEDICA or its agents at premises controlled by IMMEDICA, (“Defective Product”) then IMMEDICA
shall have the right to reject such shipment of Product if the entire shipment is nonconforming, or the portion thereof that fails to
so conform, as the case may be. IMMEDICA shall give notice to the LICENSOR of its rejection hereunder, as soon as practical after IMMEDICA’s
physical receipt of such shipment in premises controlled by IMMEDICA, specifying the grounds for such rejection. LICENSOR will not be
responsible for any Defective Product as a result of transport delays or Product mishandling in each case caused by IMMEDICA or its agents.
If LICENSOR has to replace Defective Product as a result of transport delays or Product mishandling caused by IMMEDICA or its agents,
IMMEDICA shall reimburse LICENSOR for its fully burdened cost of Manufacture and supply of the replacement Product. Notwithstanding the
foregoing, and solely until the expiration of the shelf-life for the applicable Product, in the event of any Defective Product which was
not obvious on receipt of such shipment, IMMEDICA shall have [*] after becoming aware of such Defective Product to notify the LICENSOR.

 

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		7.9.2.	IMMEDICA’s grounds for rejection shall be conclusive unless the LICENSOR notifies IMMEDICA, within
[*] of receipt by the LICENSOR of the notice of rejection, that it disagrees with such grounds. In the event of such a notice by the LICENSOR,
representative samples of the Defective Product in question shall be submitted to a mutually acceptable independent laboratory or consultant
(if not a laboratory analysis issue) for analysis or review, the costs of which shall be paid by the Party that is determined by the independent
laboratory or consultant to have been incorrect in its determination of whether the applicable Product should be rejected.

 

		7.9.3.	In the event of any Defective Product, at IMMEDICA’s sole discretion, the LICENSOR shall either,
at the election of IMMEDICA: (i) replace such Defective Product, as soon as possible, and in any event within [*] after receipt of notice
of rejection thereof, or (ii) reimburse IMMEDICA for any out-of-pocket costs incurred by IMMEDICA associated with the Defective Product
(including all labeling and packaging costs, handling costs and transportation costs).

 

	7.10.	Product Recall.

 

		7.10.1.	If either Party becomes aware of information about distributed Product indicating that it may be non-conforming
with respect to the Specifications, Applicable Law, GMP, or the terms of the Quality Agreement, or that there is potential adulteration,
misbranding and/or any potential issues regarding safety or effectiveness with respect to the Product, it shall promptly serve written
notice to that effect on the other Party. If such issue relates to a Defective Product, the LICENSOR shall initiate an investigation and
assessment of such circumstances and shall provide IMMEDICA a written report of its findings and any proposed course of action to remedy
such issue.

 

		7.10.2.	In the event: (i) any Regulatory Authority or other national government authority issues a request, directive
or order that Product be recalled; (ii) a court of competent jurisdiction orders such a recall; or (iii) IMMEDICA reasonably determines
that Product should be recalled, the Parties shall take all appropriate corrective actions, and shall cooperate in any governmental investigations
surrounding the recall. In the event the LICENSOR reasonably determines that Product should be recalled, the LICENSOR shall provide notice
to IMMEDICA including all relevant information that supports such determination. Upon receipt of any such notice, IMMEDICA shall promptly
initiate a Product recall. IMMEDICA will have the responsibility for all communications with Regulatory Authorities in the Territory and
customers regarding any recall of Product in the Field. The LICENSOR will give IMMEDICA any assistance that IMMEDICA may reasonably request
to handle any recall.

 

		7.10.3.	In the event that such recall results from a Defective Product that was a Defective Product at the time
of delivery of the Product, including the breach of the LICENSOR’ s express warranties under Section 7.11, or the LICENSOR’s
negligence, recklessness or willful misconduct (a “LICENSOR Caused Recall”), the LICENSOR shall at IMMEDICA’s option,
promptly replace the quantity of Products that were recalled at no cost to IMMEDICA, or reimburse IMMEDICA for any out-of-pocket costs
incurred by IMMEDICA associated with the Products that were recalled (including all labeling and packaging costs, handling costs and transportation
costs). In the event that IMMEDICA elects to have the recalled Product replaced, the LICENSOR shall replace such Product as soon as possible.
In the event that IMMEDICA elects to be reimbursed for out-of-pocket costs associated with the recalled Products, the LICENSOR shall reimburse
IMMEDICA within [*] of receipt of request from IMMEDICA for reimbursement. In addition, the LICENSOR agrees that it shall be responsible
for the expenses of any such LICENSOR Caused recall. For purposes of this Agreement, the expenses of the recall shall include the expenses
of notification, and destruction or return of the recalled Product, and any costs associated with the distribution of the replacement
Product. In the event that the recall was not a LICENSOR Caused Recall, then to the extent such recall affects Products in the Territory
in the Field, the LICENSOR shall not be responsible for the expenses of the recall or for replacing or reimbursing the relevant Products.

 

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	7.11.	Supply Specific Representations and Warranties

 

		7.11.1.	Services. The LICENSOR represents, warrants and covenants that: (a) it shall perform all Services
in a professional manner, with due care and in accordance with industry standards; and (b) it shall perform all Services in accordance
with: (i) Applicable Laws; (ii) GMP; and (iii) the terms and conditions of this Agreement.

 

		7.11.2.	Product Warranties. The LICENSOR warrants and covenants that all Product delivered to IMMEDICA
pursuant to this Agreement shall conform with the Specificiations and the certificate of analysis, and shall be Manufactured in accordance
with GMP and in compliance with Applicable Laws.

 

	8.	RECORDS; AUDIT RIGHTS; INSPECTIONS

 

	8.1.	Records.

 

		8.1.1.	IMMEDICA’s Records. IMMEDICA shall maintain, and cause its Affiliates and Sublicensees to
maintain, accurate financial books and records pertaining to the sale of the Product by IMMEDICA, its Affiliates and its Sublicensees,
as applicable, including any and all calculations of the applicable Fees (collectively, “Relevant Records”). IMMEDICA
shall maintain the Relevant Records for the longer of: (a) the period of time required by Applicable Law, or (b) [*] following the
end of the Calendar Year to which such books and records pertain.

 

		8.1.2.	The LICENSOR’s Records. The LICENSOR shall maintain, and cause its Affiliates and subcontractors
to maintain, at the LICENSOR’s cost, complete and accurate records related to the performance of LICENSOR’s obligations under
this Agreement, including in relation to all Services and Clinical Studies and any costs that LICENSOR incurs that are to be reimbursed
by IMMEDICA (the “LICENSOR Records”). LICENSOR shall provide IMMEDICA reasonable access to the LICENSOR Records upon
the written request of IMMEDICA. Such access shall be requested in writing at least [*] in advance, and shall be conducted during the
LICENSOR’s normal business hours and otherwise in manner that minimizes any interference to the LICENSOR’s business operations.
The LICENSOR shall retain the LICENSOR Records, together with samples representing each batch of the Product delivered to IMMEDICA under
this Agreement for at least [*] for LICENSOR Records and [*] after expiration of shelf-life for samples in each case from the shipment
of the relevant batch of Product to IMMEDICA or such longer period as required by Applicable Laws.

 

	8.2.	Audit Rights.

 

		8.2.1.	Audit Request. LICENSOR shall have the right during the term of this Agreement and for [*] thereafter
to engage, at its own expense, an independent auditor reasonably acceptable to IMMEDICA to examine the Relevant Records from time-to-time,
but no more frequently than [*], as may be necessary to verify the amounts reported by IMMEDICA and IMMEDICA’s compliance with the
terms of this Agreement. Such audit shall be requested in writing at least [*] in advance, and shall be conducted during IMMEDICA’s
normal business hours and otherwise in manner that minimizes any interference to IMMEDICA’s business operations. Such audits may
not (i) be conducted for any Calendar Year ending more than [*] prior to the date of such request, (ii) be conducted more than
[*] in any Calendar Year or (iii) be [*] for any Calendar Quarter.

 

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		8.2.2.	Audit Fees and Expenses. Upon completion of any audit pursuant to Section 8.2.1, the independent
auditor shall provide to the Parties a copy of its audit report disclosing any issues or discrepancies identified. LICENSOR shall bear
any and all fees and expenses it may incur in connection with any such audit of the Relevant Records; provided, however, in the event
an audit reveals an underpayment by IMMEDICA of more than [*] as to the period subject to the audit, IMMEDICA shall reimburse LICENSOR
for the reasonable and documented fees and expenses charged by such independent auditor in connection with such audit.

 

		8.2.3.	Payment of Deficiency. If any audit establishes that IMMEDICA underpaid any amounts due to LICENSOR
under this Agreement, then IMMEDICA shall pay LICENSOR any such deficiency, plus interest calculated in accordance with Section 6.1.5
from the date on which the payment was originally due, within [*] after receipt of written notice thereof. In the event such audit establishes
that amounts were overpaid by IMMEDICA during such period, the amount of such overpayment plus interest calculated in accordance with
Section 6.1.5 shall be credited against future amounts owed by IMMEDICA provided always that in the event an audit is conducted within
the last [*] of the Term, such amount will be repaid to IMMEDICA.

 

		8.2.4.	Confidential Financial Information. The LICENSOR shall treat all financial information subject
to review under this Section 8 as confidential and shall cause its independent auditor to retain all such financial information in confidence
on terms no less restrictive than those applicable to the LICENSOR under Section 11 below.

 

	8.3.	Inspections.

 

		8.3.1.	Each Party shall promptly notify the other Party of any regulatory inspections that may impact the other
Party’s rights or obligations under this Agreement. The LICENSOR shall provide all reasonable co-operation to any inspection by
any Regulatory Authority responsible for the approval of the Product in the Territory and shall facilitate reasonable access to the Facility
and all LICENSOR Records. Unless not permitted by such Regulatory Authority, in the event of an inspection at the LICENSOR’s premises
or the Facility, IMMEDICA shall have the right (subject to Section 8.3.4 with respect to any Facility owned or controlled by a Third Party)
to have a representative present during the portion of the inspection that involves the Product.

 

		8.3.2.	The LICENSOR shall, unless not permitted to do so by the Regulatory Authority, forward to IMMEDICA copies
of any and all correspondence from and with any Regulatory Authority responsible for the approval of the Product in the Territory. To
the extent the Product is implicated in regulatory inspection findings, the LICENSOR will provide a draft of the pertinent responses to
IMMEDICA for review and comment prior to submission to the relevant Regulatory Authority responsible for the approval of the Product in
the Territory; provided that the inspected entity is responsible for all responses to observations made by a Regulatory Authority and
is not obligated to modify responses based upon IMMEDICA’s comments.

 

		8.3.3.	. The LICENSOR shall promptly, and in any event within [*], after the LICENSOR becomes aware notify IMMEDICA
in writing of any written observation, violation or deficiency noted, by a Regulatory Authority responsible for the approval of the Product
in the Territory, following an inspection which related to or which may affect the Product or activities undertaken pursuant to this Agreement.
The LICENSOR shall promptly rectify, and shall use reasonable efforts to cause its manufacturers to rectify, any such violation or deficiency
at the LICENSOR’s sole cost and expense.

 

		8.3.4.	Where any part of the Manufacturing process is undertaken by a Third Party on behalf of the LICENSOR,
LICENSOR shall procure that such Third Party shall comply with the obligations set out in this Section 8.3. In respect of IMMEDICA’
s right to have a representative present during an inspection pursuant to Section 8.3.1, LICENSOR’s obligation will be to use
its reasonable efforts to allow IMMEDICA to attend such inspection.

 

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	9.	INTELLECTUAL PROPERTY RIGHTS

 

	9.1.	Pre-existing IP. Each Party shall retain all rights, title and interests in and to any Intellectual
Property Rights that are owned, licensed or sublicensed by such Party prior to or independent of this Agreement.

 

	9.2.	Ownership of Inventions. Inventorship of inventions shall be determined in accordance with the
rules of inventorship under U.S. patent laws. As between the Parties, IMMEDICA (or its Affiliate) shall solely own all inventions made
solely by IMMEDICA personnel, and the LICENSOR (or its Affiliate) shall solely own all inventions made solely by personnel of the LICENSOR.
The Parties (or their respective Affiliates) shall jointly own all inventions made jointly by personnel of both IMMEDICA and the LICENSOR;
provided that, subject to the rights and licenses granted under and the restrictions set forth in this Agreement, each Party may practice
and exploit any such joint invention and/or any jointly owned Patent Rights to the extent such practice and exploitation does not infringe
the Intellectual Property Rights of the other Party, including, without limitation, in connection with its development, manufacture and/or
commercialization of products, without the consent of, or a duty of accounting to, the other Party, and each Party hereby waives any right
it may have under applicable law to require such consent or accounting.

 

	9.3.	License of Developed IP. Any Patent Rights that are conceived, developed or reduced to practice
by or on behalf of IMMEDICA as a direct result of the performance of its activities under this Agreement are, to the extent they are Controlled
by IMMEDICA (“Developed IP”), hereby licensed to the LICENSOR on a non-exclusive, fully paid-up basis, for the sole
and limited purpose of the Development, Manufacture, and Commercialization of the Product in all territories and countries of the world
other than the Territory (provided that after any termination of this Agreement, the foregoing license shall be worldwide).

 

	9.4.	Recording of License. If either Party considers it advisable to record IMMEDICA as a licensee or
“registered user” of any of the Licensed Technology under local law, the other Party shall do all such acts and sign or have
signed all such documents as are reasonably proper and necessary to secure such recordation and for any changes thereof in the future.
In such event, the relevant Party is responsible for recording this Agreement or a document reflecting this Agreement’s contents
with any applicable governmental authority and for all associated recordation fees and related costs and expenses. Upon termination of
IMMEDICA’s rights under this Agreement, either Party may at any time thereafter apply for cancellation of the record of IMMEDICA
as a licensee (in the case of LICENSOR, upon written notice to IMMEDICA).

 

	9.5.	Patent and Trademark Prosecution.

 

		9.5.1.	Patent and Trademark Prosecution and Maintenance. Subject to IMMEDICA’s rights set forth
in Section 9.5.3 and Section 9.5.4, the LICENSOR will be responsible for filing, prosecuting (including in connection with any
reexaminations, oppositions and the like), defending and maintaining the Licensed Patents and all Product Trademarks in all countries
in the Territory in LICENSOR’s name at LICENSOR’s own cost and expense.

 

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		9.5.2.	Assistance.

 

		(a)	The LICENSOR shall inform IMMEDICA as to the prosecution and maintenance and defence of the Licensed Patents
and Product Trademarks in the Territory prior to any deadline, submission to or action with any patent or trademark office, and shall
furnish to IMMEDICA copies of all relevant drafts and documents of such Licensed Patents or relating to the Product trademarks reasonably
in advance of such consultation. The LICENSOR shall provide to IMMEDICA copies of all patent office and trademark submissions and correspondence
relevant to such Licensed Patents and Product Trademarks within a reasonable amount of time following submission or receipt thereof by
the LICENSOR. The LICENSOR shall consider in good faith any reasonable and timely comments provided by IMMEDICA in connection with the
prosecution and maintenance and defence of such Licensed Patents and Product Trademarks. LICENSOR will discuss and agree with IMMEDICA
any proposal to opt-in or opt-out of the proposed Unified Patent Court system should that come into effect or to designate a Licensed
Patent as a Unitary Patent.

 

		(b)	IMMEDICA will provide reasonable assistance to LICENSOR, at LICENSOR’s expense, in connection with
the filing, prosecution and maintenance and defence of such Licensed Patents and Product Trademarks, where such assistance shall include
providing access to relevant persons and executing all documentation reasonably requested by LICENSOR.

 

		(c)	As reasonably requested by LICENSOR in writing and at LICENSOR’s expense, IMMEDICA shall cooperate
in obtaining patent term restoration (under, but not limited to, the Drug Price Competition and Patent Term Restoration Act), supplementary
protection certificates or their equivalents, and patent term extensions with respect to the Licensed Patents in Europe.

 

		9.5.3.	Failure to Prosecute or Maintain. In the event LICENSOR elects to forgo filing, prosecution or
maintenance or defence of any of the Licensed Patents or Product Trademarks in any country in the Territory, LICENSOR shall promptly notify
IMMEDICA of such election, but in any event at least [*] prior to any filing or payment due date, or any other due date that requires
action (“Election Notice”). Upon receipt of an Election Notice, IMMEDICA shall be entitled, upon written notice to
LICENSOR, at its sole discretion and expense, to file or to continue the prosecution or maintenance of such Licensed Patent or Product
Trademarks in such country in LICENSOR’s name using counsel of its own choice and at its own expense, provided that IMMEDICA shall
keep the LICENSOR reasonably informed as to the material actions taken with regard to the prosecution and maintenance and defence of such
Licensed Patents and Product Trademarks in the Territory. The LICENSOR shall cooperate with IMMEDICA to transfer the prosecution and maintenance
of such Licensed Patent and Product Trademarks, together with all relevant documentation and the file wrapper, to IMMEDICA. If requested
by IMMEDICA, the LICENSOR shall ensure that the LICENSOR’s patent or trademark attorney liaises with IMMEDICA’s patent attorney
to ensure a smooth and complete transfer of prosecution and maintenance obligations.

 

		9.5.4.	Trademarks.

 

			The Parties recognize the importance of having a coordinated global approach to the use of
                                                                                trademarks in relation to the Product and to that end and to the extent reasonably possible in accordance with Appl: able Law agree
                                                                                to use the same trademarks on Product inside the Territory and outside the Territory. LICENSOR in consultation with IMMEDICA, shall
                                                                                be responsible for the creation, filing, registration, and prosecution and maintenance of the Product Trademarks in the Territory.
                                                                                LICENSOR, in consultation with IMMEDICA, shall undertake the searching and clearance of all potential Product Trademarks within the
                                                                                Territory as soon as reasonably possible following the Effective Date. If LICENSOR fails to apply for trademarks for the Product
                                                                                within the Territory reasonably in advance of IMMEDICA’S intended launch of the Product in the Territory IMMEDICA shall be
                                                                                free to do so and shall own all resulting trademarks. IMMEDICA shall use the Product Trademarks registered by LICENSOR in connection
                                                                                with the Product in the Field within the Territory.

 

	10.	INFRINGEMENT; MISAPPROPRIATION

 

	10.1.	Notification. Each Party will promptly notify the other Party in writing of any actual or threatened
infringement, misappropriation or other violation by a Third Party of any Licensed Technology or any Product Trademark in the Territory
of which it becomes aware (“Third Party Infringement”).

 

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	10.2.	Infringement Action.

 

		10.2.1.	Right of First Enforcement.

 

		(a)	LICENSOR shall have the first right (but not the obligation), at its own expense, to control enforcement
of the Licensed Technology and Product Trademarks against any Third Party Infringement (each an “Enforcement Action”),
after having conferred with IMMEDICA. LICENSOR shall keep IMMEDICA reasonably updated with regard to the progress of any such Enforcement
Action that it takes. LICENSOR shall give IMMEDICA timely notice of any proposed settlement of any such action instituted by LICENSOR
and shall not enter into any settlement that would: (i) admit the liability of IMMEDICA or its Affiliates, or (ii) materially affect the
scope of validity of any Licensed Patent or Trademark, or (iii) materially adversely effect the Commercialization of the Product in the
Territory, in each case with respect to the foregoing clauses (i)-(iii), without the prior written consent of IMMEDICA, which consent
shall not be unreasonably withheld, conditioned or delayed.

 

		(b)	If LICENSOR does not initiate proceedings within [*] from the date of IMMEDICA’s request that LICENSOR
initiate such proceedings, then IMMEDICA shall have the right but shall not be obliged, upon prior written notice to LICENSOR, to initiate
infringement proceedings or take other action it believes appropriate against such Third Party Infringement at its own expense.

 

		10.2.2.	Assistance. At the request and sole cost and expense of the Party controlling an Enforcement
                                                                          Action, the other Party shall provide reasonable assistance in connection therewith. If one Party brings any suit, action or
                                                                          proceeding under this Section 10.2, the other Party agrees to be joined as party plaintiff if reasonably necessary to prosecute the
                                                                          suit, action or proceeding and to give the first Party authority to file, prosecute and control the suit, action or proceeding;
                                                                          provided however that such non- controlling Party shall have the right, at its own expense, to be represented in any such action in
                                                                          which it is a party by independent counsel of its own choice.

 

		10.2.3.	Recoveries. Any recoveries resulting from an action relating to a claim of Third Party Infringement
shall first be applied against payment of each Party’s costs and expenses incurred in connection therewith. Any remaining recoveries
shall be retained by IMMEDICA; provided that LICENSOR shall be entitled to a Royalty on such remaining recoveries at the applicable rate
set forth in Section 6.1 as if the amount of such remaining recoveries were Net Sales of IMMEDICA in the Calendar Year in which the
recoveries were received by IMMEDICA. Notwithstanding the foregoing, any recoveries resulting from an action relating to a claim of Third
Party Infringement shall not be included in the calculation of any commercial milestones under Section 1.2 of Schedule B.

 

		10.2.4.	Third Party Infringement Claims. If the Development, Manufacture or Commercialization of any Product
in any country of the Territory pursuant to this Agreement results in a claim, suit or proceeding alleging patent or other intellectual
property infringement against the LICENSOR or IMMEDICA (or their respective Affiliates, or Sublicensees) (collectively, “Infringement
Actions”), such Party shall promptly notify the other Party hereto in writing. IMMEDICA shall be indemnified in respect of any
such Infringement Action in accordance with Section 13.1 and LICENSOR shall have the right to direct and control the defense thereof,
at its own expense with counsel of its choice in accordance with Section 13.3. LICENSOR shall keep IMMEDICA reasonably informed of all
material developments in connection with any such Infringement Action.

 

	11.	CONFIDENTIALITY

 

	11.1.	Definition. “Confidential Information” means the terms and provisions of this Agreement
and other proprietary information and data of a financial, commercial or technical nature that the disclosing Party or any of its Affiliates
has supplied or otherwise made available to the other Party or its Affiliates, whether disclosed in writing, orally or otherwise. The
terms of this Agreement shall be considered the Confidential Information of both Parties.

 

	11.2.	Obligations. During the term of this Agreement, and for [*] thereafter (or, in the case of Confidential
Information constituting a trade secret, for such longer period of time that the Confidential Information remains a trade secret under
Applicable Law), the receiving Party will protect all Confidential Information against unauthorized access, use or disclosure to Third
Parties with the same degree of care as the receiving Party uses for its own similar information, but in no event less than a reasonable
degree of care. The receiving Party may disclose the Confidential Information to its Affiliates, and their respective directors, officers,
employees, subcontractors, consultants, attorneys, and accountants, banks (to the extent required by applicable borrowing documentation)
and investors who hold a majority of the voting equity of a Party (collectively, “Recipients”) who (a) have a
need-to-know such information for purposes related to this Agreement, (b) are informed of the confidential nature of the Confidential
Information and the receiving Party’ s obligations hereunder, and (c) are bound by written obligations of confidentiality with terms
and conditions at least as restrictive as those set forth in this Agreement.

 

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	11.3.	Exceptions.

 

		11.3.1.	The obligations under this Section 11 shall not apply to any information to the extent the receiving Party
can demonstrate by competent evidence that such information:

 

		(a)	is (at the time of disclosure) or becomes (after the time of disclosure) known to the public or part of
the public domain through no breach of this Agreement by the receiving Party or any Recipients to whom it disclosed such information;

 

		(b)	was known to, or was otherwise in the possession of, the receiving Party prior to the time of disclosure
by the disclosing Party;

 

		(c)	is disclosed to the receiving Party on a nonconfidential basis by a Third Party who is entitled to disclose
it without breaching any confidentiality obligation to the disclosing Party; or

 

		(d)	is independently developed by or on behalf of the receiving Party or any of its Affiliates, as evidenced
by its written records, without use or access to the Confidential Information.

 

		11.3.2.	Notwithstanding anything herein to the contrary, the receiving Party may disclose Confidential Information
to the extent such disclosure is required under Applicable Laws or a court order or other governmental order, provided that the receiving
Party: (a) provides the disclosing Party with prompt notice of such disclosure requirement if legally permitted, (b) affords the
disclosing Party an opportunity to oppose or limit, or secure confidential treatment for such required disclosure and (c) if the
disclosing Party is unsuccessful in its efforts pursuant to subsection (b), discloses only that portion of the Confidential Information
that the receiving Party is legally required to disclose as advised by the receiving Party’s legal counsel. Confidential Information
disclosed pursuant to this Section 11 shall remain subject to the restrictions set forth herein for all other purposes.

 

		11.3.3.	In the event that LICENSOR wishes to assign, pledge or otherwise transfer its rights to receive some or
all of the Milestone Payments and Royalties payable hereunder, LICENSOR may disclose to a Third Party such Confidential Information of
IMMEDICA as LICENSOR deems reasonably necessary in connection with any such proposed assignment, provided that LICENSOR shall hold such
Third Parties to written obligations of confidentiality with terms and conditions at least as restrictive as those set forth in this Agreement.

 

		11.3.4.	IMMEDICA may disclose Confidential Information of the LICENSOR to the extent such disclosure is reasonably
necessary in the following instances:

 

		(a)	with LICENSOR’ s written consent (such consent not to be unreasonably withheld, conditioned or delayed),
filing for, prosecuting or enforcing Licensed Patents in accordance with this Agreement;

 

		(b)	in Regulatory Filings or otherwise in seeking, obtaining and maintaining Regulatory Approvals (including
complying with the requirements of Regulatory Authorities with respect to filing for, obtaining and maintaining such Regulatory Approvals);

 

		(c)	the Development and/or Commercialization of the Product in the Territory, provided, that any Third Party
to whom IMMEDICA discloses Confidential Information pursuant to this clause (c) (i) are informed of the confidential nature
of the Confidential Information and IMMEDICA’s obligations hereunder and (ii) are bound by written obligations of confidentiality
with terms and conditions at least as restrictive as those set forth in this Agreement; and

 

		(d)	disclosing to actual or bona fide potential Sublicensees or subcontractors in connection with the
exercise of its rights under this Agreement or related activities, provided, that such Sublicensees and subcontractors (i) are informed
of the confidential nature of the Confidential Information and IMMEDICA’s obligations hereunder and (ii) are bound by written
obligations of confidentiality with terms and conditions at least as restrictive as those set forth in this Agreement.

 

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		11.3.5.	Each Party shall be responsible for any breaches of confidentiality by any of its Affiliates, subcontractors,
Sublicensees, Recipients, advisors and Third Parties to whom it discloses Confidential Information pursuant to Section 11.

 

		11.3.6.	Confidential Disclosure of Terms. Each Party agrees not to disclose to any Third Party the existence
and/or terms of this Agreement without the prior written consent of the other Party hereto, except as permitted under this Section 11,
and notwithstanding the foregoing, each Party may disclose the existence and/or terms of this Agreement to its advisors (including financial
advisors, attorneys and accountants), potential and existing investors, collaboration partners or acquirers, and others on a reasonable
need to know basis, in each case under circumstances that reasonably protect the confidentiality thereof.

 

	11.4.	Right to Injunctive Relief. The Parties agree that breaches of this Section 11 may cause irreparable
harm to the non-breaching Party and shall entitle the non-breaching Party, in addition to any other remedies available to it (subject
to the terms of this Agreement), the right to seek injunctive relief enjoining such action, and each Party hereby waives any requirement
to post a bond or other security or prove actual damages or that monetary damages will not afford an adequate remedy.

 

	11.5.	Ongoing Obligation for Confidentiality. Upon expiration or termination of this Agreement, the receiving
Party shall, and shall cause its Recipients to, destroy or return (as requested by the disclosing Party) any Confidential Information
of the disclosing Party, except for one copy which may be retained in its confidential files for archive purposes.

 

	11.6.	Data Protection Regulations. Each Party will collect, use, and disclose information governed by
this Agreement in compliance with all applicable privacy and data protection laws, rules, and regulations and in accordance with the terms
of a data sharing agreement that will be agreed by the Parties acting reasonably and in good faith within [*] of the Effective Date. The
Parties shall enter into any additional agreements regarding the collection, use, processing or disclosure of such information as mandated
by such data protection laws, rules and regulations. The Parties shall notify each other promptly of any unauthorized uses or disclosures
of such information of which they become aware.

 

	12.	REPRESENTATIONS, WARRANTIES AND COVENANTS

 

	12.1.	Representations and Warranties by Each Party. Each Party represents and warrants to the other Party
as of the Effective Date that:

 

		12.1.1.	it is a corporation duly organized, validly existing, and in good standing under the laws of its jurisdiction
of formation;

 

		12.1.2.	it has full corporate power and authority to execute, deliver, and perform this Agreement, and has taken
all corporate action required by Applicable Law and its organizational documents to authorize the execution and delivery of this Agreement
and the consummation of the transactions contemplated by this Agreement;

 

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		12.1.3.	this Agreement constitutes a valid and binding agreement enforceable against it in accordance with its
terms;

 

		12.1.4.	all consents, approvals and authorizations from all governmental authorities or other Third Parties required
to be obtained by such Party in connection with this Agreement have been obtained; and

 

		12.1.5.	the execution and delivery of this Agreement and all other instruments and documents required to be executed
pursuant to this Agreement, and the consummation of the transactions contemplated hereby do not and shall not: (i) conflict with or result
in a breach of any provision of its organizational documents, (ii) result in a breach of any agreement to which it is a party that would
impair the performance of its obligations hereunder; or (iii) violate any Applicable Law.

 

	12.2.	Representations and Warranties by LICENSOR. LICENSOR represents and warrants to IMMEDICA as of the Effective Date that:

 

		12.2.1.	there is no actual alleged or threatened claim that has been notified in writing to the Licensor or its
Affiliates or, to its Knowledge, any pending or possible claim that the Development, Manufacture or Commercialization of the Product within
the Territory infringes, misappropriates or otherwise violates the Intellectual Property Rights of a Third Party. As used in this Section
12.2, “Knowledge” means knowledge of the officers of LICENSOR, and is not meant to require or imply that any particular
inquiry or investigation has been undertaken including, without limitation, obtaining any type of search (independent of that performed
by the actual governmental authority during the normal course of patent prosecution, as applicable, in a jurisdiction) or opinion of counsel,
provided that it shall include the knowledge that would be obtained from reasonable inquiries that a person in that position would normally
be expected to have made;

 

		12.2.2.	there is no actual, pending, alleged or threatened claim by LICENSOR or its Affiliate alleging that a
Third Party is or was infringing, misappropriating or otherwise violating the Licensed Technology within the Territory;

 

		12.2.3.	to its Knowledge, the practice of the Licensed Patents or the Licensed Know-How and the Development, Manufacture
and/or Commercialization of any Product does not infringe, violate or misappropriate the Intellectual Property Rights of any Third Party;

 

		12.2.4.	Schedule A sets forth a true and complete list of all Licensed Patents Controlled by the LICENSOR
or its Affiliates as of the Effective Date that Cover the Product, and the LICENSOR has the full right and authority to grant to IMMEDICA
the right to use, sell, offer to sell, import and sublicense the Patent Rights in the Territory described in Schedule A, and to
enforce such Patent Rights in accordance with Section 10 above;

 

		12.2.5.	the LICENSOR has not previously granted and will not grant any right, license or interest in or to a Product,
Licensed Know-How and/or Licensed Patents, or any portion thereof, that is in conflict with, limits or derogates from the rights or licenses
granted to IMMEDICA under this Agreement;

 

		12.2.6.	the Licensed Patents and the Licensed Know-How are free and clear of all liens, claims, security interests
or other encumbrances of any kind and during the term of this Agreement, the LICENSOR shall not permit the Licensed Patents or the Licensed
Know-How to become encumbered by any liens, claims, security interests or other encumbrances, in each case of the foregoing that could
diminish IMMEDICA’s rights or licenses with respect to Licensed Patent Rights;

 

		12.2.7.	the LICENSOR has not knowingly withheld any Licensed Know-How that is reasonably relevant for IMMEDICA’s
conduct of activities under this Agreement and, to the LICENSOR’S Knowledge, all Licensed Know-How provided to IMMEDICA is free
from any material inaccuracies;

 

		12.2.8.	the LICENSOR has disclosed to IMMEDICA all material information relating to the safety and efficacy of
the Product known to it or its Affiliates;

 

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		12.2.9.	the LICENSOR has complied with all Applicable Laws, including any disclosure requirements, in connection
with the filing, prosecution and maintenance of the Licensed Patents and, to the LICENSOR’s Knowledge, none of the issued Licensed
Patents are invalid or unenforceable;

 

		12.2.10.	the LICENSOR has conducted, and its contractors and consultants have conducted, all its Development activities
relating to the Product, including the Phase III Clinical Trial, in accordance with Applicable Laws including, as applicable, GLP and
GCP;

 

		12.2.11.	neither the LICENSOR nor any of its Affiliates are, or have been, debarred or disqualified by any Regulatory
Authority; and none of the LICENSOR or any of its Affiliates’ employees or contractors who were involved in the Development, Manufacture
or Commercialization of the Product are, or have been, debarred or disqualified by any Regulatory Authority;

 

		12.2.12.	the materials and documents provided to IMMEDICA in the course of IMMEDICA’s due diligence preceding
execution of this Agreement were free from any material inaccuracies;

 

		12.2.13.	the LICENSOR has made available to IMMEDICA all material information in the LICENSOR’s or its Affiliate’s
control relating to the Development and Manufacture of the Products as conducted by or on behalf of the LICENSOR and its Affiliates prior
to the Effective Date, including complete and correct copies of the following: adverse event reports; clinical study reports and material
study data; and Regulatory Authority inspection reports, notices of adverse findings, warning letters, Regulatory Filings and other material
correspondence with Regulatory Authorities;

 

		12.2.14.	neither the LICENSOR nor any of its employees have been “debarred” by the FDA or the EMA,
or subject to a similar sanction from another Regulatory Authority, nor have debarment proceedings against the LICENSOR or any of its
employees been commenced. The LICENSOR will promptly notify IMMEDICA in writing if any such proceedings have commenced or if the LICENSOR
or any of its employees are debarred by the FDA or the EMA or any other Regulatory Agency;

 

		12.2.15.	it shall not hire or retain as an officer or employee any person who has been convicted of a felony under
the laws of the United States for conduct relating to the regulation of any drug product under the FDCA. If at any time this representation
and warranty is no longer accurate, the LICENSOR shall immediately notify IMMEDICA of such fact;

 

		12.2.16.	all personal data and biological specimens collected from or disclosed by human subjects in Clinical Studies
of the Products have been collected, used, processed and disclosed in compliance with Applicable Laws;

 

		12.2.17.	to the Knowledge of the LICENSOR, the Phase III Clinical Trial will, if it meets its primary endpoints,
produce sufficient clinical data to support an application for Regulatory Approval of the Product in AML with the EMA without the need
for additional Clinical Studies, provided that this representation and warranty shall not be taken as a representation and or warranty
that the Phase III Clinical Trial will meet its primary endpoints or that any application for Regulatory Approval for the Product will
be successful;

 

		12.2.18.	the Existing Agreements are in full force and effect and the Licensor has complied in all material respects
with each of its obligations the Existing Agreements in a timely manner, and has paid all payments owed by the LICENSOR under the Existing
Agreements in full and on time;

 

		12.2.19.	the LICENSOR is not in breach of any material term of the Manufacturing Agreements and, to its Knowledge,
no counterparty to the Manufacturing Agreements is in breach of any material term of the Manufacturing Agreements; and

 

		12.2.20.	to its Knowledge, the Facility meets all requirements under Applicable Law, including under GMP, for the
Manufacture of the Product for Commercialization in the European Union.

 

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	12.3.	Representations and Warranties by IMMEDICA. IMMEDICA represents and warrants to LICENSOR as of
the Effective Date that:

 

		12.3.1.	to its Knowledge, the practice of the Licensed Patents or the Licensed Know-How and the Development, Manufacture
and/or Commercialization of any Product within the Territory does not infringe, violate or misappropriate the Intellectual Property Rights
of any Third Party. As used in this Section 12.3, “Knowledge” means knowledge of the officers of IMMEDICA, and
is not meant to require or imply that any particular inquiry or investigation has been undertaken including, without limitation, obtaining
any type of search (independent of that performed by the actual governmental authority during the normal course of patent prosecution,
as applicable, in a jurisdiction) or opinion of counsel, provided that it shall include the knowledge that would be obtained from reasonable
inquiries that a person in that position would normally be expected to have made; and

 

		12.3.2.	to its Knowledge, the granted patents within the Licensed Patents are valid and enforceable.

 

	12.4.	No Other Warranties. EXCEPT AS EXPRESSLY STATED IN THIS SECTION 12, NEITHER PARTY MAKES ANY
REPRESENTATIONS OR EXTENDS ANY WARRANTIES OF ANY KIND, EITHER EXPRESS OR IMPLIED, STATUTORY OR OTHERWISE, INCLUDING BUT NOT LIMITED TO
WARRANTIES OF TITLE, NON- INFRINGEMENT, VALIDITY, ENFORCEABILITY, MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE.

 

	12.5.	Maintenance of the Existing Agreements.

 

		12.5.1.	On an Existing Agreement-by-Existing Agreement basis, the LICENSOR shall ensure that such Existing Agreement
is not terminated, revoked or allowed to expire during the term of this Agreement for any reason attributable to the LICENSOR. The LICENSOR
shall:

 

		(a)	not terminate such Existing Agreement without first obtaining IMMEDICA’s express written consent
to such termination;

 

		(b)	ensure that it complies, at all times, with each of its obligations under such Existing Agreement in a
timely manner, and shall ensure that all payments owed by the LICENSOR under such Existing Agreement are paid in full and on time; and

 

		(c)	not agree or consent to any amendment, supplement, or other modification (including termination) to such
Existing Agreement which could adversely affect IMMEDICA’s rights under this Agreement without IMMEDICA’s prior written consent.

 

	12.6.	Maintenance of the Manufacturing Agreements.

 

		12.6.1.	On a Manufacturing Agreement-by-Manufacturing Agreement basis, from and after the Effective Date, the
LICENSOR shall ensure that such Manufacturing Agreement is not terminated, revoked or allowed to expire during the term of this Agreement
for any reason attributable to the LICENSOR. The LICENSOR shall:

 

		(a)	not terminate such Manufacturing Agreement without first obtaining IMMEDICA’s express written consent
to such termination (such consent not to be unreasonably withheld, conditioned or delayed);

 

		(b)	ensure that it complies, at all times, with each of its obligations under such Manufacturing Agreement
in a timely manner, and shall ensure that all payments owed by the LICENSOR under such Manufacturing Agreement are paid in full and on
time; and

 

		(c)	not agree or consent to any amendment, supplement, or other modification (including termination) to such
Manufacturing Agreement which could adversely affect IMMEDICA or the supply of Product under this Agreement without IMMEDICA’s prior
written consent (such consent not to be unreasonably withheld, conditioned or delayed).

 

Notwithstanding
the foregoing, LICENSOR shall have the right without needing the consent of IMMEDICA to utilize other manufacturers provided that LICENSOR
shall be responsible for any studies necessary to demonstrate the equivalence of the Product manufactured at such other manufacturers
and the terms of any agreements with such manufacturers, to the extent such terms impact IMMEDICA’s rights or the LICENSOR’s
ability to supply Product under the terms of this Agreement, are no less favourable in any material respect than the terms of the Manufacturing
Agreements. LICENSOR shall continue to supply the Product to IMMEDICA without amendment until such time as any change or variation to
a Regulatory Approval that is required as a result of such use of alternative manufacturers is approved by the applicable Regulatory Authority.
If the LICENSOR proposes to enter into any new agreements with Third Parties relating to the Manufacture of the Product it shall notify
IMMEDICA in writing and such proposal shall be discussed at the JSC. LICENSOR shall keep IMMEDICA reasonably informed with regard to the
progress of any discussions with any such Third Party and will provide to IMMEDICA a copy of any agreement entered into with such a Third
Party.

 

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		12.6.2.	The LICENSOR covenants that promptly and in any event within [*] of the Effective Date, subject to Section 12.6.l(c),
LICENSOR shall put in place an amendment to each of the Manufacturing Agreements to cover clinical and commercial supply of the Product
to IMMEDICA in the Territory as contemplated by this Agreement.

 

	13.	INDEMNIFICATION

 

	13.1.	Indemnification by LICENSOR. The LICENSOR agrees to indemnify, hold harmless and defend IMMEDICA,
its Affiliates and Sublicensees and their respective officers, directors, employees, contractors, agents and assigns (collectively the
“IMMEDICA Indemnitees”), from and against any Claims arising or resulting from (a) the Development of a Product,
including the performance of any Clinical Studies by the LICENSOR, its Affiliates, or respective subcontractors, (b) any breach by the
LICENSOR of any representation, warranty or covenant as set forth in this Agreement, (c) any Claim or allegation that the Development,
Manufacture and Commercialization of the Product in the Territory infringes the Intellectual Property Rights of a Third Party (including
any Infringement Action) or (d) the negligence, recklessness or wrongful intentional acts or omissions of any Licensor Indemnitees; except
to the extent in each case (a) to (c) such Claims result from the breach of this Agreement by IMMEDICA, or the negligence, recklessness
or wrongful intentional acts or omissions of any IMMEDICA Indemnitees.

 

	13.2.	Indemnification by IMMEDICA. IMMEDICA agrees to indemnify, hold harmless and defend LICENSOR and
its Affiliates, and their respective officers, directors, employees, contractors, agents and assigns (collectively, “Licensor
Indemnitees”), from and against any Claims arising or resulting from: (a) the Development of a Product by IMMEDICA, its Affiliates,
its Sublicensees or their respective subcontractors, (b) the Commercialization of a Product by IMMEDICA, its Affiliates, its Sublicensees,
or their respective subcontractors, (c) the negligence, recklessness or wrongful intentional acts or omissions of IMMEDICA, its Affiliates,
its Sublicensees or their respective subcontractors, or (d) breach by IMMEDICA of any representation, warranty or covenant as set forth
in this Agreement; except to the extent in each case (a) to (d), such Claims result from the breach of this Agreement by the LICENSOR,
or the negligence, recklessness or wrongful intentional acts or omissions of any Licensor Indemnitees.

 

	13.3.	Indemnification Procedure. In connection with any Claim for which a Party (the “Indemnitee”)
seeks indemnification from the other Party (the “Indemnitor”) pursuant to this Agreement, the Indemnitee shall:
(a) give the Indemnitor prompt written notice of the Claim; provided, however, that failure to provide such notice shall not relieve the
Indemnitor from its liability or obligation hereunder, except to the extent of any material prejudice as a direct result of such failure;
(b) cooperate with the Indemnitor, at the Indemnitor’s expense, in connection with the defense and settlement of the Claim; and
(c) permit the Indemnitor to control the defense and settlement of the Claim; provided, however, that the Indemnitor may not settle the
Claim without the Indemnitee’s prior written consent, which shall not be unreasonably withheld, conditioned or delayed, in the event
such settlement materially adversely impacts the Indemnitee’s rights or obligations. Further, the Indemnitee shall have the right
to participate (but not control) and be represented in any suit or action by advisory counsel of its selection and at its own expense.

 

	13.4.	Third Party Intellectual Property. If a Third Party notifies IMMEDICA, its Affiliates, distributors
or Sublicensees that Intellectual Property Rights owned or controlled by such Third Party cover the use or sale of the Product in the
Territory (“Third Party IP Rights”), then IMMEDICA shall, upon becoming aware of such notice, promptly notify LICENSOR
(“Third Party Notice”) and give LICENSOR the exclusive right to negotiate with such Third Party. If LICENSOR obtains
a license or other right from such Third Party for such Third Party IP Rights, LICENSOR shall ensure that LICENSOR has the right to sublicense
to IMMEDICA under this Agreement, and LICENSOR shall bear all costs and expenses of such license (including milestones and royalties).
In any event, from the date of LICENSOR’s receipt of the Third Party Notice, LICENSOR shall indemnify, hold harmless and defend
the IMMEDICA Indemnitees from and against any Claims from such Third Party with respect to the infringement of the Third Party IP Rights
from the use or sale of the Product in the Territory.

 

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	14.	LIMITATION OF LIABILITY

 

	14.1.	Consequential Damages Waiver. EXCEPT FOR A BREACH
OF SECTION 11, NEITHER PARTY SHALL BE LIABLE FOR ANY LOSS OF GOODWILL, REPUTATION, BUSINESS, REVENUES, INDIRECT PROFITS, ANTICIPATED
PROFITS, CONTRACTS, OR OPPORTUNITIES (REGARDLESS OF HOW THESE ARE CLASSIFIED AS DAMAGES) OR ANY INDIRECT, CONSEQUENTIAL, SPECIAL, EXEMPLARY
OR PUNITIVE DAMAGES, REGARDLESS OF WHETHER IT HAS BEEN INFORMED OF THE POSSIBILITY OR LIKELIHOOD OF SUCH DAMAGES OR THE TYPE OF CLAIM,
CONTRACT OR TORT (INCLUDING NEGLIGENCE).

 

NOTHING
IN THIS AGREEMENT EXCLUDES OR LIMITS ANY LIABILITY FOR DEATH OR PERSONAL INJURY CAUSED BY NEGLIGENCE, FOR FRAUD OR FOR ANY OTHER LIABILITY
WHICH CANNOT LEGALLY BE EXCLUDED OR LIMITED.

 

NOTWITHSTANDING
THE FOREGOING, THE LIMITATIONS SET FORTH IN THIS SECTION 14.1 SHALL NOT LIMIT AN INDEMNITOR’ S LIABILITY FOR DAMAGES AWARDED
TO ANY THIRD PARTY IN CONNECTION WITH ANY CLAIM FOR WHICH A PARTY IS ENTITLED TO INDEMNIFICATION UNDER SECTION 13.

 

NOTWITHSTANDING
ANY OTHER PROVISION IN THIS SECTION 14.1, THE LICENSOR SHALL NOT BE LIABLE FOR ANY LOSS OF PROFIT CLAIMED BY IMMEDICA TO THE EXTENT SUCH
LOSS OF PROFIT ARISES FROM AN ACT OR OMISSION OF A THIRD PARTY SUPPLIER TO LICENSOR AND THE TERMS OF THE CONTRACT BETWEEN LICENSOR AND
SUCH THIRD PARTY SUPPLIER EXCLUDES OR LIMITS THE RECOVERY OF SUCH LOSS OF PROFIT.

 

A
PARTY’S AGGREGATE LIABILITY FOR ANY AND ALL CLAIMS BY THE OTHER PARTY FOR ANY DIRECT LOSS OF PROFIT ARISING OUT OF OR IN CONNECTION
WITH THIS AGREEMENT SHALL NOT EXCEED

 

[*]
OF THE TOTAL OF ANY SUMS WHICH HAVE BEEN PAID BY IMMEDICA TO LICENSOR UNDER THIS AGREEMENT EXCLUDING, EXCEPT IN THE CASE OF AN INTENTIONAL
BREACH BY LICENSOR WITHIN [*] OF THE EFFECTIVE DATE, THE UPFRONT PAYMENT REFERRED TO IN SECTION 6.1.1,

 

TOGETHER
WTTH

 

A
SUM EQUIVALENT TO [*] OF THE TOTAL VALUE OF NET PROFIT ON SALES OF THE PRODUCT ACHIEVED BY IMMEDICA IN THE [*] PRIOR TO THE DATE ON WHICH
THE MATTER GIVING RISE TO THE CLAIM FIRST AROSE.

 

	15.	TERM; TERMINATION

 

	15.1.	Term. The term of this Agreement shall commence as of the Effective Date and shall continue until
terminated in accordance with this Section 15.

 

	15.2.	Termination for Cause. Each Party shall have the right, without prejudice to any other remedies
available to it at law or in equity, to terminate this Agreement in the event the other Party is in material breach of this Agreement
and fails to cure such breach within [*] of receiving notice thereof; provided, however, if such breach is capable of being cured,
but cannot be cured within such [*] period, and the breaching Party initiates actions to cure such breach within such period and thereafter
diligently pursues such actions, the breaching Party shall have such additional period as is reasonable to cure such breach, but in no
event will such additional period exceed [*]. Any termination by a Party under this Section 15.2 shall be without prejudice to any damages
or other legal or equitable remedies to which it may be entitled from the other Party.

 

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	15.3.	Termination for a Bankruptcy Event. Each Party shall have the right to terminate this Agreement
in the event of a Bankruptcy Event with respect to the other Party. “Bankruptcy Event” means the occurrence of any
of the following: (a) the institution of any bankruptcy, receivership, insolvency, reorganization or other similar proceedings by or against
a Party under any bankruptcy, insolvency, or other similar law now or hereinafter in effect, including any section or chapter of the United
States Bankruptcy Code, as amended or under any similar laws or statutes of the United States or any state thereof (the “Bankruptcy
Code”), where in the case of involuntary proceedings such proceedings have not been dismissed or discharged within [*] after
they are instituted, (b) the insolvency of a Party or making of an assignment for the benefit of creditors, (c) the institution of any
reorganization, arrangement or other readjustment of debt plan of a Party not involving the Bankruptcy Code, or (d) appointment of a receiver
for all or substantially all of a Party’s assets (each an “Insolvency Event”). All rights and licenses now or
hereafter granted by the LICENSOR to IMMEDICA under or pursuant to this Agreement, including, for the avoidance of doubt, the license
granted to IMMEDICA pursuant to Section 2.1, are, for all purposes of Section 365(n) of the Bankruptcy Code, licenses of rights to
“intellectual property” as defined in the Bankruptcy Code. Upon the occurrence of any Insolvency Event with respect to LICENSOR,
the LICENSOR agrees that IMMEDICA, as licensee of such rights under this Agreement, shall retain and may fully exercise all of its rights
and elections under the Bankruptcy Code. Without limiting the generality of the foregoing, the LICENSOR and IMMEDICA intend and agree
that any sale of the LICENSOR’s assets under Section 363 of the Bankruptcy Code shall be subject to IMMEDICA’s rights under
Section 365(n), that IMMEDICA cannot be compelled to accept a money satisfaction of its interests in the intellectual property licensed
pursuant to this Agreement, and that any such sale therefore may not be made to a purchaser “free and clear” of IMMEDICA’s
rights under this Agreement and Section 365(n) without the express, contemporaneous consent of IMMEDICA.

 

	15.4.	Termination for Challenge to Licensed Technology. LICENSOR shall have the right to terminate this
Agreement at any time after the Effective Date on [*] written notice in its entirety or on a country-by-country basis in the event IMMEDICA
or any of its Affiliates or Sublicensees contests or challenges, or supports or assists any Third Party to contest or challenge, in any
patent office, court, regulatory agency or other forum, the validity, enforceability or scope of, any of the Licensed Patents (a “Patent
Challenge”); provided that if a Licensed Patent is asserted against IMMEDICA, or any of its Affiliates or Sublicensees in an
infringement action or other legal proceeding with respect to activities outside the licenses granted herein, or any sublicense granted
hereunder, then any claim or action taken in defense of such assertion shall not be deemed a Patent Challenge. Any termination for Patent
Challenge shall be subject to the notification and cure procedure set out in Section 15.2, including a right for IMMEDICA to withdraw
or rectify the Patent Challenge during the cure period in which case LICENSOR shall have no right to terminate this Agreement at the end
of the cure period if the Patent Challenge has been so withdrawn or rectified. Any attempt to cure a breach of this Section 15.4
requires IMMEDICA to reimburse LICENSOR for any and all expenses and costs, including all legal fees, incurred as a result of the Patent
Challenge.

 

	15.5.	Termination by IMMEDICA. IMMEDICA shall have the right to terminate this Agreement in its entirety,
or on a country-by-country basis, without cause, and for any or no reason on not less than [*] prior written notice to the LICENSOR.

 

	15.6.	Effect of Termination or Expiration.

 

		15.6.1.	Upon termination or expiration of this Agreement, IMMEDICA shall pay to LICENSOR all amounts due to LICENSOR
as of the effective date of termination or expiration within [*] following the effective date of termination or expiration.

 

		15.6.2.	Upon termination of this Agreement, IMMEDICA shall have the right to sell its remaining inventory of Product
following the termination of this Agreement so long as IMMEDICA has fully paid, and continues to fully pay when due, any and all Royalties
owed to LICENSOR, and IMMEDICA otherwise is not in material breach of this Agreement.

 

		15.6.3.	Upon termination of this Agreement but not expiration, all licenses granted by one Party to the other
Party shall terminate. For clarity, termination of the licenses granted by LICENSOR to IMMEDICA shall terminate all sublicenses granted
by IMMEDICA hereunder.

 

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		15.6.4.	With the exception of termination of this Agreement by IMMEDICA pursuant to Section 15.2 or 15.3, upon
termination of this Agreement:

 

		(a)	To the extent permitted by applicable Regulatory Authorities, IMMEDICA shall, at IMMEDICA’s cost:
(i) transfer, or cause to be transferred, to LICENSOR all Regulatory Filings and Regulatory Approvals held by IMMEDICA, its Affiliates
and its Sublicensees with respect to the Product, and (ii) to the extent subsection (i) is not permitted by the applicable Regulatory
Authority, permit LICENSOR, or cause its Affiliates and its Sublicensees to permit LICENSOR to cross-reference and rely upon any Regulatory
Approvals and Regulatory Filings owned by IMMEDICA, its Affiliates and its Sublicensees with respect to the Product.

 

	15.7.	Survival. Expiration or termination of this Agreement shall not relieve the Parties of any obligation
accruing hereunder prior to such expiration or termination. Without limiting the foregoing, the provisions of Sections 1, 5.4, 7.10, 8.1,
8.2, 8.3, 9.1, 9.2, 9.3, 9.4, 11, 13, 15.6, 18 and 19 shall survive expiration or termination of this Agreement.

 

	16.	PUBLICITY

 

	16.1.	Publicity.

 

		16.1.1.	Subject to IMMEDICA’s rights pursuant to Section 2.1.2, neither Party (nor any of its Affiliates
or agents) shall use the trademarks of the other Party or its Affiliates in any press release, publication or other form of promotional
disclosure without the prior written consent of the other Party in each instance.

 

		16.1.2.	The Parties have mutually approved a press release attached hereto as Schedule D with respect
to this Agreement. Each Party agrees not to issue any other press release or other public statement, whether written, electronic, oral
or otherwise, disclosing the existence of this Agreement, the terms hereof or any information relating to this Agreement without the prior
written consent of the other Party, provided however, that (i) neither Party will be prevented from complying with any duty
of disclosure it may have pursuant to Applicable Law or the rules of any recognized stock exchange so long as the disclosing Party provides
the other Party prior written notice to the extent practicable and only discloses information to the extent required, in the reasonable
opinion of such Party’s legal counsel, by Applicable Law or the rules of any recognized stock exchange, (ii) once the press
release set out in Schedule D has been released, each Party may disclose the information contained in such press release without
further consent, and (iii) IMMEDICA shall have the right to publicly disclose without the LICENSOR’s prior written consent:
(A) the achievement of any milestone under this Agreement ; or (B) any information (other than Confidential Information of Licensor)
relating to the Development or Commercialization of any Products in the Territory.

 

	17.	INSURANCE

 

	17.1.	Insurance Requirements. The Parties will each maintain during the term of this Agreement and for
[*] after termination or expiration of this Agreement, commercial general liability insurance from a minimum [*] rated insurance company,
including contractual liability and product liability or clinical trials, if applicable, with coverage limits of [*] per occurrence and
[*] in the aggregate. Each Party has the right to provide the total limits required by any combination of primary and umbrella/excess
coverage. The minimum level of insurance set forth herein shall not be construed to create a limit on a Party’s liability hereunder.

 

	17.2.	Policy Notification. On request, each Party shall provide the other Party with certified copies
of such policies or original certificates of insurance evidencing such insurance: (a) prior to execution by both Parties of this Agreement,
and (b) prior to expiration of any such coverage.

 

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	18.	DISPUTE RESOLUTION

 

	18.1.	General. Except for disputes for which injunctive or other equitable relief is sought to prevent
the unauthorized use or disclosure of proprietary materials or information or prevent the infringement or misappropriation of a Party’s
Intellectual Property Rights, the following procedures shall be used to resolve any dispute arising out of or in connection with this
Agreement.

 

	18.2.	Meeting. Promptly after the written request of either Party, each of the Parties shall appoint
a designated representative to meet in person or by telephone to attempt in good faith to resolve any dispute arising out of or in connection
with this Agreement. If the designated representatives do not resolve the dispute within [*] of such request, then an executive officer
of each Party shall meet in person or by telephone to review and attempt to resolve the dispute in good faith. The executive officers
shall have [*] to attempt to resolve the dispute.

 

	18.3.	Arbitration.

 

		18.3.1.	 Any disputes arising out of or in connection with this
Agreement, including any question regarding its existence, validity or termination that are not otherwise resolved by the Parties in
accordance with Section 18.2 shall be finally settled under the Rules of Arbitration of the International Chamber of Commerce by one
or more arbitrators appointed in accordance with the said Rules. The Parties agree, pursuant to Article 30(2)(b) of said Rules that the
Expedited Procedure Rules shall apply irrespective of the amount in dispute. The language of the arbitration shall be English. The number
of arbitrators shall be one; provided that if the Parties fail to nominate a mutually acceptable sole arbitrator within [*] from the
date when the Request for Arbitration has been received by the other Party, the number of arbitrators shall be three. The seat, or legal
place, of arbitration shall be London, England.

 

		18.3.2.	The arbitrator(s) shall not be an officer or employee of either Party. The cost of the arbitration, including
the fees and expenses of the arbitrator(s), will be shared equally by the Parties. The prevailing Party shall be entitled to recover from
the losing Party the prevailing Party’s arbitration costs, including reasonable attorneys’ fees and costs and the fees and
expenses of the arbitrator(s). The arbitration award will be presented to the Parties in writing, and upon the request of either Party,
will include findings fact and conclusions of law. The award may be confirmed and enforced in any court of competent jurisdiction.

 

		18.3.3.	If a Party asserted to be in breach under Section 15.2 above disputes the asserted breach, this Agreement
shall not be terminated and the licenses herein shall not be affected as a result of the disputed breach unless and until it has been
determined in accordance with this Section 18.3 that this Agreement was materially breached, and such breach is not cured within [*] after
such determination or such longer period as the arbitrator may establish.

 

	19.	GENERAL PROVISIONS

 

	19.1.	Compliance. The Parties shall conduct their business in accordance with all Applicable Laws. Without
limiting the generality of the foregoing, each Party further acknowledges and ensures that it and its Affiliates, Sublicensees and subcontractors
are familiar with the provisions of the United States Foreign Corrupt Practices Act, the UK Bribery Act and applicable local bribery and
corruption laws, and shall not take or permit any action that will either constitute a violation under, or cause the other Party to be
in violation of, the provisions of the United States Foreign Corrupt Practices Act, the UK Bribery Act or applicable local bribery and
corruption law or other Applicable Laws (collectively, “Improper Conduct”). In addition to any other rights either
Party may have under this Agreement, if a Party (the “Improper Party”) notifies the other Party of, or if such other
Party otherwise has a reasonable suspicion of, the occurrence of Improper Conduct, such other Party shall have the right to have an independent
auditor inspect the premises, books and records of the Improper Party relevant to such Improper Conduct for the purpose of ensuring compliance
under this Section 19.1.

 

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	19.2.	Assignment and Subcontracting. Neither Party may assign its rights and obligations under this Agreement
without the other Party’s prior written consent, except that: (a) LICENSOR may assign to a Third Party its rights to receive some
or all of the Fees payable hereunder, (b) each Party may assign its rights and obligations under this Agreement or any part hereof to
one or more of its Affiliates without the consent of the other Party; (c) LICENSOR may assign this Agreement in its entirety without the
consent of IMMEDICA to a successor to all or substantially all of its business to which this Agreement relates; and (d) IMMEDICA may assign
this Agreement in its entirety without the consent of LICENSOR to a successor to all or substantially all of its business to which this
Agreement relates provided that such successor is not a Competitor. For purposes of this Section 19.2, “Competitor” means
a Third Party that is Developing or commercializing an antibody, or another biological therapeutic molecule, directed to the Target in
the Field. The assigning Party shall provide the other Party with prompt written notice of any such assignment. Any permitted assignee
pursuant to clauses (b), (c) and (d) above shall assume all obligations of its assignor under this Agreement, and no permitted assignment
shall relieve the assignor of liability for its obligations hereunder. The LICENSOR shall not assign or otherwise transfer to any Affiliate
or any Third Party any ownership interest in or to any Licensed Know-How or Licensed Patent, unless (i) the LICENSOR’s entire
business associated with the Product, including all Manufacturing rights relating to the Product, are assigned to such Affiliate or Third
Party and (ii) this Agreement is concurrently assigned therewith. Any attempted assignment in contravention of the foregoing shall be
void. Each Party shall be entitled to appoint subcontractors to carry out its obligations under this Agreement provided that such subcontractors
are engaged under contracts that are consistent with the terms of this Agreement and such subcontracting shall not relieve a Party of
its obligations under this Agreement.

 

	19.3.	Severability. Should one or more of the provisions of this Agreement become void or unenforceable
as a matter of law, then such provision will be ineffective only to the extent of such prohibition or invalidity, without invalidating
the remainder of this Agreement, and the Parties agree to substitute a valid and forceable provision therefor which, as nearly possible,
achieves the desired economic effect and mutual understanding of the Parties under this Agreement.

 

	19.4.	Governing Law. This Agreement and any issues, disputes or claims arising out of or in connection
with it (whether contractual or non-contractual in nature such as claims in tort, from breach of statute or regulation or otherwise) shall
be governed by, and construed in accordance with, the laws of England and Wales, without giving effect to any conflicts of laws provision
thereof or of any other jurisdiction that would produce a contrary result, except that issues subject to the arbitration clause and any
arbitration hereunder shall be governed by the applicable commercial arbitration rules and regulations.

 

	19.5.	Force Majeure. Except with respect to delays or nonperformance caused by the negligent or intentional
act or omission of a Party, any delay or nonperformance by such Party (other than payment obligations under this Agreement) will not be
considered a breach of this Agreement to the extent such delay or nonperformance is caused by acts of God, natural disasters, acts of
the government or civil or military authority, fire, floods, epidemics, pandemics, quarantine, energy crises, war or riots or other similar
cause outside of the reasonable control of such Party (each, a “Force Majeure Event”), provided that the Party affected
by such Force Majeure Event will promptly begin or resume performance as soon as reasonably practicable after the event has abated. In
the event that the Force Majeure Event is a recognized widespread epidemic or pandemic (including the current COVID-19 pandemic) that
delays or renders impracticable or unsafe the performance by either or both of the Parties under this Agreement, the Parties will negotiate
in good faith appropriate modifications to this Agreement to allow performance hereunder that is consistent with the health and safety
of the Parties, their representatives, the general public and/or any participants in any Clinical Studies.

 

	19.6.	Waivers and Amendments. The failure of any Party to assert a right hereunder or to insist upon
compliance with any term or condition of this Agreement shall not constitute a waiver of that right or excuse a similar subsequent failure
to perform any such term or condition by the other Party. No waiver shall be effective unless it has been given in writing and signed
by the Party giving such waiver. No provision of this Agreement may be amended or modified other than by a written document signed by
authorized representatives of each Party.

 

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	19.7.	Relationship of the Parties. Nothing contained in this Agreement shall be deemed to constitute
a partnership, joint venture, or legal entity of any type between LICENSOR and IMMEDICA, or to constitute one Party as the agent of the
other. Moreover, each Party agrees not to construe this Agreement, or any of the transactions contemplated hereby, as a partnership for
any tax purposes. Each Party shall act solely as an independent contractor, and nothing in this Agreement shall be construed to give any
Party the power or authority to act for, bind, or commit the other Party.

 

	19.8.	Successors and Assigns. This Agreement shall be binding upon and inure to the benefit of the Parties
hereto and their respective successors and permitted assigns.

 

	19.9.	Notices. All notices, consents, waivers, and other communications under this Agreement must be
in writing and will be deemed to have been duly given when: (a) delivered by hand (with written confirmation of receipt), (b) sent by
email (with confirmation of receipt), provided that a copy is also sent by an internationally recognized overnight delivery service (receipt
requested), or (c) when received by the addressee, if sent by an internationally recognized overnight delivery service (receipt requested),
in each case to the appropriate addresses and email addresses set forth below (or to such other addresses and email addresses as a Party
may designate by written notice):

 

If to LICENSOR:

 

Actinium Pharmaceuticals, Inc.

275 Madison Avenue, Suite 702

New York, New York, 10016

Email: [*]

Attention: General Counsel

With a copy addressed to the CFO at

Email: [*]

 

If to IMMEDICA:

 

Immedica Pharma AB

Norrtullsgatan 15

SE 113 29 Stockholm

Sweden

Email: [*]

Attention: General Counsel

With a copy addressed to the CEO at

Email: [*]

 

	19.10.	Further Assurances. IMMEDICA and LICENSOR hereby covenant and agree without the necessity of any
further consideration, to execute, acknowledge and deliver any and all such other documents and take any such other action as may be reasonably
necessary or appropriate to carry out the intent and purposes of this Agreement.

 

	19.11.	No Third Party Beneficiary Rights. This Agreement is not intended to and shall not be construed
to give any Third Party any interest or rights (including, without limitation, any third party beneficiary rights) with respect to or
in connection with any agreement or provision contained herein or contemplated hereby.

 

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	19.12.	Entire Agreement.

 

		(a)	This Agreement, together with its Schedules, sets forth the entire agreement and understanding of the
Parties as to the subject matter hereof and supersedes all proposals, oral or written, and all other prior communications between the
Parties with respect to such subject matter.

 

		(b)	In the event of any conflict between a material provision of this Agreement and any Schedule hereto, the
Agreement shall control.

 

	19.13.	Interpretation. The headings of Sections of this Agreement are not a part of this Agreement, but
are included for convenience of reference and shall not affect its meaning or interpretation. In this Agreement: (a) the word “
including” shall be deemed to be followed by the phrase “without limitation” or like expression; (b) the singular shall
include the plural and vice versa; and (c) masculine, feminine and neuter pronouns and expressions shall be interchangeable. Each accounting
term used herein that is not specifically defined herein shall have the meaning given to it under generally accepted cost accounting principles,
but only to the extent consistent with its usage and the other definitions in this Agreement.

 

	19.14.	Counterparts. This Agreement may be executed in two or more counterparts, each of which shall be
deemed an original, but all of which together shall constitute one and the same instrument. Delivery of an executed counterpart of a signature
page to this Agreement bye- mail of a .pdf attachment shall be effective as delivery of a manually executed counterpart of this Agreement.

 

	19.15.	Cumulative Remedies. No remedy referred to in this Agreement is intended to be exclusive, but each
shall be cumulative and in addition to any other remedy referred to in this Agreement or otherwise available under law.

 

	19.16.	Waiver of Rule of Construction. Each Party has had the opportunity to consult with counsel in connection
with the review, drafting and negotiation of this Agreement. Accordingly, any rule of construction that any ambiguity in this Agreement
shall be construed against the drafting Party shall not apply.

 

[Signature page(s) follow]

 

    41

     

    

 

IN WITNESS WHEREOF, the Parties
intending to be bound have caused this Agreement to be executed by their duly authorized representatives as of the Effective Date.

 

	Actinium Pharmaceuticals, Inc.	 	Immedica Pharma AB
	 	                            	 	 
	By:	/s/ Sandesh Seth	 	By:	/s/ Anders Edvell
	Name:	Sandesh Seth	 	Name: 	Anders Edvell
	Title:	CEO	 	Title:	CEO

 

    

    	

    

 

 

 

SCHEDULE A: PATENT RIGHTS

 

[*]

 

    

    	

    

 

SCHEDULE B: PAYMENTS

 

		1.	PAYMENTS

 

		1.1.	Upfront Payment. In consideration of the licenses and rights granted to IMMEDICA hereunder, IMMEDICA shall
pay to LICENSOR a one-time upfront, non-refundable and non-creditable payment of US$35,000,000 (in words: thirty five million US dollars).

 

		1.2.	Milestone Payments.

 

		1.2.1.	In further consideration of the licenses and rights granted to IMMEDICA hereunder, upon first achievement
of each Milestone set forth below, the corresponding non-creditable and non-refundable Milestone Payments shall be payable by IMMEDICA
to LICENSOR:

 

	REGULATORY MILESTONES	MILESTONE PAYMENT
	[*]	[*]

For the purposes of the milestones
in the table above “Indication” shall mean a separate and distinct indication requiring a separate Regulatory Approval. Assuming
that the first Indication is conditioning treatment for bone marrow transplantation in AML, the second and third Indications shall not
be conditioning treatment for bone marrow transplant in AML.

 

	COMMERCIAL MILESTONES	MILESTONE PAYMENT
	[*]	[*]

 

		1.2.2.	For the avoidance of doubt: (i) each Milestone Payment shall be payable only once upon the first achievement
of the applicable Milestone; (ii) satisfaction of a Milestone by an Affiliate of IMMEDICA or Sublicensee of IMMEDICA shall be deemed to
have been satisfied by IMMEDICA for purposes of this Section 1.2 of Schedule B; (iii) the total Regulatory Milestones
shall not, in any circumstances, exceed [*]; and (iii) the total Commercial Milestones shall not, in any circumstances, exceed [*].

 

		1.3.	Royalties.

 

		1.3.1.	Royalty Rate. In consideration of the licenses and rights granted to IMMEDICA hereunder, IMMEDICA
will pay to LICENSOR Royalties on Net Sales of Product in the Territory, where such Royalties shall be calculated each Calendar Quarter
by multiplying the Net Sales for such Calendar Quarter by the applicable rate set forth in the table below, subject to the provisions
of this Section 1.3 of Schedule B. For clarity, the Royalties are inclusive of the cost of supply of Product under this Agreement.

 

	TIME PERIOD OF NET SALES	ROYALTY RATE
	[*]	[*]

 

		1.3.2.	One Royalty: No more than one royalty payment shall be due under this Agreement with respect to
each sale of a Product in the Field in the Territory.

 

    

    	

    

 

SCHEDULE C: THE SPECIFICATIONS

 

[*]

 

    

    	

    

 

SCHEDULE
D: PRESS RELEASE

 

 [*]Exhibit 10.2

 

EXECUTION COPY

 

 

 

 

 

 

 

 

 

 

 

AGREEMENT OF SUBLEASE

 

between

 

ABN AMRO HOLDING USA LLC

 

as Sublandlord

 

and

 

ACTINIUM PHARMACEUTICALS, INC.

 

as Subtenant

 

 

 

Premises: Entire 23rd Floor

100 Park Avenue 

New York, New York 10017

 

 

 

 

 

 

 

 

 

 

 

 

 

 

     

     

    

 

AGREEMENT OF SUBLEASE

 

THIS AGREEMENT OF SUBLEASE (this “Sublease”),
made and entered into as of the __ day of April, 2022, by and between ABN AMRO HOLDING USA LLC, a Delaware limited liability company,
having offices at 100 Park Avenue, New York, New York 10017 (“Sublandlord”), and ACTINIUM PHARMACEUTICALS, INC., a Delaware
corporation, having offices at 275 Madison Avenue, New York, New York 10016 (“Subtenant”).

 

W I T N E S S E T H:

 

WHEREAS, SLG 100 Park LLC, (“Landlord”)
leased to Sublandlord’s predecessor-in interest certain premises (the “Original Premises”) at 100 Park Avenue, New York,
New York 10017 (the “Building”), pursuant to a certain Lease Agreement (the “Original Lease”) dated as of July
10, 2009, as amended by a certain First Lease Modification and Additional Space Agreement (the “First Amendment”) dated as
of March 1, 2011, a certain Second Lease Modification and Additional Space Agreement (the “Second Amendment”) dated as of
January 31, 2014 and a certain Third Lease Modification and Additional Space Agreement (the “Third Amendment”) dated as of
March 31, 2017, (the Original Lease, as amended by the First Amendment, the Second Amendment and the Third Amendment, is hereinafter referred
to as the “Lease” and the premises currently leased by Sublandlord pursuant to the Lease are hereinafter referred to as the
“Premises”); and

 

WHEREAS, Subtenant desires to sublease the entire
23rd floor portion of the Premises (the “Subleased Premises”) consisting of approximately 10,889 rentable square
feet, as more particularly described in “Exhibit A” which is attached to this Sublease as an integral part hereof, from Sublandlord,
and Sublandlord is willing to sublease the Subleased Premises to Subtenant, upon the terms and conditions hereinafter set forth;

 

NOW, THEREFORE, in consideration of the foregoing
premises and the mutual covenants and obligations herein contained, the parties hereby agree as follows:

 

1. Subleased Premises. Sublandlord
hereby subleases the Subleased Premises to Subtenant, and Subtenant hereby hires the Subleased Premises from Sublandlord, upon and subject
to the terms and conditions set forth herein.

 

2. Term of Sublease. The term of this
Sublease (the “Term”) shall commence on the later of (a) the date upon which a written consent to this Sublease is issued
by Landlord following the signing of this Sublease by Sublandlord and Subtenant and (b) June 1, 2022 (the “Commencement Date”),
and shall terminate on July 30, 2027 (the “Expiration Date”), unless sooner terminated as provided herein. Sublandlord shall
deliver vacant possession of the Subleased Premises to Subtenant in their “as is” condition and broom clean on the Commencement
Date, and Subtenant shall accept such possession.

 

3. Fixed
Rent.

 

(a) Subject
to the increases stipulated in Paragraph 4(b) below, during the term of this Sublease, Subtenant shall pay Sublandlord fixed rent (“Fixed
Rent”) for the Subleased Premises in the amount of Five Hundred Ninety Eight Thousand Eight Hundred Ninety Five and 00/100 Dollars
($598,895.00) per annum, payable in advance in equal monthly installments of Forty Nine Thousand Nine Hundred Seven and 92/100 Dollars
($49,907.92) on or before the first day of each month.

 

    1

     

    

 

(b) Notwithstanding
anything to the contrary in the foregoing, Subtenant shall pay the first monthly installment of Fixed Rent upon the signing of this Sublease
by Subtenant.

 

(c) The
Fixed Rent for any portion of a calendar month falling within the Term shall be prorated.

 

(d) Fixed
Rent and all other amounts payable by Subtenant to Sublandlord under this Sublease (such other amounts are herein called “Additional
Rent”) shall be paid promptly when due, without notice or demand therefor, without deduction, abatement, counterclaim, or setoff
of any kind for any reason whatsoever.

 

(e) Fixed
Rent and Additional Rent shall be paid in U.S. Dollars and by wire transfer or ACH to such account of Sublandlord as Sublandlord may from
time to time designate by notice to Subtenant.

 

(f) Notwithstanding
the foregoing, provided that Subtenant is not then in default under this Sublease, the Fixed Rent payable for the first five (5) months
after the Commencement Date shall be abated at no cost or expense to Subtenant. If Subtenant during such five (5) month abatement period
defaults (after a failure to cure following any applicable notice and cure period) under this Sublease, the rent abatement for the balance
of such period shall be forfeited, and Subtenant shall pay to Sublandlord, within five (5) days after demand, the Fixed Rent which would
have been payable for the prior portion of the abatement period but for the abatement.

 

4. Additional Rent.

 

(a) Except
as otherwise provided herein, during the term of this Sublease, Subtenant shall pay Sublandlord as Additional Rent all amounts payable
by Sublandlord to Landlord as Additional Rent for the Subleased Premises pursuant to the Lease as and when such amounts are due under
the Lease.

 

(b) In
lieu of payments on account of “Expenses” and “Real Estate Taxes” (as those terms are defined in the Lease), the
parties agree that the Fixed Rent payable by Subtenant pursuant to Paragraph 3(a) above shall be increased annually at a compound rate
of two percent (2%) per annum, with the increases to take place on the first anniversary of the Commencement Date and on each subsequent
anniversary thereof.

 

(c) During
the term of this Sublease, Subtenant shall pay Sublandlord for electricity supplied to the Subleased Premises at the rate of 105% of Landlord’s
Cost (as defined in the Lease) of the Subtenant’s usage as shown on the submeter located in Subleased Premises as and when payments
on account of electricity are due under the Lease.

 

(d) In
the case of any of Additional Rent payments which are not due on a regular basis on the first day of the month, Sublandlord shall give
Subtenant fifteen (15) days’ prior written notice thereof.

 

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5. Subordination to and Incorporation of Lease,
Etc.

 

(a) Obligations.
Subtenant confirms that it has read the Lease and is familiar with all of the terms and provisions set forth therein. Subject to the modifications
and exclusions set forth in this Sublease, the terms, provisions , covenants, stipulations, conditions, rights, obligations, remedies,
agreements and definitions contained in the Lease are incorporated herein by reference and are made a part hereof and shall, as between
Sublandlord and Subtenant (as if they were the “Landlord” and the “Tenant,” respectively, under the Lease and
as if the Subleased Premises were the Premises referred to in the Lease), constitute the terms of this Sublease as if herein set forth
at length, mutatis mutandis, except to the extent that they do not relate to the Subleased Premises or are inapplicable, inconsistent
with, or modified by the terms of this Sublease, and except as otherwise set forth herein. Subtenant agrees to observe, carry out, perform
and discharge the terms and provisions of the Lease as they relate to the Subleased Premises to the extent required to be observed, carried
out, performed or discharged by Sublandlord thereunder, except where inapplicable or inconsistent with the terms of this Sublease.

 

(b) Subordination,
Etc. Subtenant hereby agrees that (i) this Sublease is and shall remain in all respects subject and subordinate to the Lease and to
any matters to which the Lease is or shall be subordinate, (ii) except to the extent otherwise expressly permitted by this Sublease, Subtenant
will occupy the Subleased Premises in accordance with the terms of the Lease, will maintain the Subleased Premises in accordance with
the provisions of the Lease as though it were the “Tenant” thereunder and will not do or cause to be done, or suffer any act
or omit to do, any act which might result in a violation of or a default under any of the terms, conditions, covenants or agreements of
the Lease.

 

(c) Conflicting
Terms. Except as otherwise specifically provided herein, in the event that any term and/or condition of this Sublease shall conflict
with, or be inconsistent with, any term and/or condition of the Lease, this Sublease will govern, unless such term and/or condition would
constitute a default under or breach of the Lease, in which case the Lease will govern. Subtenant shall not take or suffer any action
which would constitute a default under, or be a violation of, the Lease.

 

(d) Excluded
Articles. The following provisions of the Lease shall be deemed to be excluded from this Sublease: (i) Original Lease – Section
1.01; Article 2; Article 3; Article 5; Article 12; Sections 13.01 through 13.03 and Section 3.05 (as they provide for Nondisturbance Agreements);
Section 13.11; Section 13.12; Article 17; Article 18; Article 22; Section 25.01 (second sentence); Article 27; Article 29; Article 31;
Article 40; Article 48; Article 50; Article 51; Article 52; Exhibit A; Exhibit B; Exhibits F-1 and F-2; Exhibit I; Exhibit J and Exhibit
K; (ii) First Amendment – Sections 3.2 through 3.6; Articles 4 through 6; Section 7.1 (last sentence); Articles 8 through 12; and
Exhibits B through D; (iii) Second Amendment – Articles 3 through 13; and Exhibits A through D; and (iv) Third Amendment –Articles
3 through 13; Exhibits A through Exhibit C.

 

(e) Termination
of Lease. In the event that the term of the Lease is terminated prior to the Expiration Date, this Sublease shall automatically cease
and terminate on the date of such termination. In the event of such termination, Sublandlord shall return to Subtenant that portion of
Fixed Rent and Additional Rent paid in advance by Subtenant, if any, pro-rated as of the date of such termination. Sublandlord agrees
that, without the prior written consent of Subtenant, it will not voluntarily agree with Landlord to terminate the Lease with respect
to the Subleased Premises prior to the Expiration Date.

 

(f) Entry
and Inspection. Sublandlord shall have the right to enter and inspect the Subleased Premises pursuant to the applicable provisions
of the Lease during business hours (except in an emergency) and upon notice (which may be given orally). Sublandlord agrees that Subtenant
and its agents may have access to the Subleased Premises prior to the Commencement Date, provided that it gives Sublandlord notice of
each proposed access at least twenty-four (24) hours in advance. Such access shall be only for taking measurements and other planning
purposes.

 

    3

     

    

 

(g) Services.
Subtenant shall be entitled to the services, utilities and repairs which Landlord is obligated to furnish or make to Sublandlord with
respect to the Subleased Premises pursuant to the terms of the Lease, but Sublandlord shall have no obligation to make any repairs or
provide such utilities or services. Sublandlord shall in no event be liable to Subtenant nor shall the obligations of Subtenant thereunder
be impaired, or the performance thereof be excused, because of any failure or delay on the part of Landlord in furnishing such services
or in making such repairs unless such failure or delay results from a default by Sublandlord under the Lease. If Landlord shall default
in any of its obligations to perform services with respect to the Subleased Premises, Sublandlord, at the reasonable cost of Subtenant,
will reasonably assist Subtenant’s efforts to obtain such services from Landlord.

 

(h) Consents
and Notices. In all provisions of this Sublease (including provisions of the Lease incorporated hereby) requiring the approval or
consent of Sublandlord, Subtenant shall be required to obtain the approval or consent of Sublandlord as well as the approval or consent
of Landlord. At the request of Subtenant, Sublandlord shall promptly apply to Landlord for any such approval or consent. In all provisions
of this Sublease (including provisions of the Lease incorporated hereby) requiring that notice be given, Subtenant shall be required to
give notice to both Sublandlord and Landlord. Notwithstanding anything to the contrary set forth in this Sublease, any covenants, representations
or other undertakings of Landlord under the Lease shall not be deemed to be made by, or otherwise constitute obligations of, Sublandlord
under this Sublease.

 

(i) Landlord’s
Consent to Sublease.

 

(A) Sublandlord
shall, promptly after execution of this Sublease by both parties, submit a copy of same to Landlord and shall use all reasonable efforts
to obtain Landlord’s consent to this Sublease; provided, however, that Sublandlord shall not be required to make any payment or commence
any action or proceeding in order to obtain Landlord’s consent to this Sublease and shall not in any event be liable to Subtenant for
any failure to obtain same (as long as Sublandlord shall have used all reasonable efforts as aforesaid to obtain Landlord’s consent to
this Sublease). Subtenant shall fully cooperate with Sublandlord in order to obtain Landlord’s consent to this Sublease, including, but
not limited to, promptly supplying such financial, business or other information or documentation as Landlord may reasonably request of
Sublandlord in connection with this Sublease. In the event that Landlord’s consent to this Sublease is not obtained within thirty five
(35) days after the date of this Sublease, either party may terminate this Sublease at any time prior to the issuance of such consent
by giving written notice of termination to the other party. If this Sublease is terminated pursuant to the immediately preceding sentence
of this Paragraph 5(i)(A), Sublandlord shall promptly return to Subtenant the first monthly installment of Fixed Rent which was paid by
Subtenant pursuant to Paragraph 3(b) above and the Security Deposit which was submitted by Subtenant pursuant to Paragraph 19(a) below
and, except as aforesaid, neither party shall have any further obligation to the other party under this Sublease.

 

(B) Landlord’s consent
to this Sublease shall not be deemed or construed to modify, amend or affect the terms and provisions of the Lease, or Sublandlord’s obligations
thereunder, which shall continue to apply to the Premises, including the Subleased Premises, and the occupants thereof, as if the Sublease
had not been made.

 

6. Use
of Subleased Premises: Quiet Enjoyment.

 

(a) Subtenant
covenants that it will use and occupy the Subleased Premises solely for the purposes expressly permitted by the Lease.

 

(b) As
long as Subtenant pays, when due, all Fixed Rent and Additional Rent due hereunder and performs and observes all of the terms, covenants
and conditions of this Sublease and the Lease, Subtenant shall have, hold and enjoy the Subleased Premises peaceably and quietly during
the Term hereof without hindrance or molestation by Sublandlord, or any party claiming through or under Sublandlord, subject to the terms
and conditions of this Sublease and the Lease.

 

    4

     

    

 

7. Improvements.
Subtenant shall be entitled to make alterations, improvements and other changes (collectively hereinafter referred to as “Sublease
Improvements”) to the Subleased Premises in accordance with the applicable provisions of the Lease and this Sublease, including
the installation of supplemental air conditioning units and/or handling equipment (it being understood that Sublandlord makes no representation
as to the availability of condenser water for any such supplemental units for purchase from Landlord). All such Sublease Improvements
shall be subject to the prior written consent of Sublandlord and Landlord. All Sublease Improvements shall be performed by Subtenant at
its sole cost and expense. Subtenant’s rights and obligations with respect to Sublease Improvements shall be governed and limited by the
relevant provisions of the Lease and this Sublease. Subtenant shall reimburse Sublandlord, within ten (10) days after written demand,
for all reasonable actual out-of-pocket costs incurred by Sublandlord for reviewing Subtenant’s plans for any proposed Sublease
Improvement and for assisting Subtenant to obtain Landlord’s consent thereto.

 

8. Default
by Subtenant.

 

(a) The
following shall constitute events of default (each an “Event of Default”):

 

 (i) if (A) Subtenant shall fail to pay any
Fixed Rent or Additional Rent on the due date thereof and such default shall continue for a period of seven (7) days after notice by Sublandlord
to Subtenant of such default (provided, however, that Sublandlord shall not be required to deliver such notice more than two (2) times
in any twelve (12) month period, it being understood that any further failure to pay any Fixed Rent or Additional Rent on the due date
thereof within such twelve (12) month period shall constitute an immediate Event of Default), or (B) Subtenant shall fail to comply with
any term, provision or covenant of this Sublease or any applicable term, provision or covenant of the Lease, or Subtenant shall violate
any rules and regulations now or hereafter established for the operation of the Building and Subtenant shall fail to remedy such failure
within fifteen (15) days after written notice from Sublandlord, or if such failure complained of shall be of a nature that the same cannot
be completely cured and remedied within said fifteen (15) day period, and Subtenant shall not (1) promptly upon the giving by Sublandlord
of such notice, advise Sublandlord of Subtenant’s intention to institute all steps necessary to remedy such situation, (2) promptly institute
and thereafter diligently pursue all steps necessary to remedy the same and (3) effect such remedy within a reasonable time (not to exceed
sixty (60) days) after the date of the giving of said notice by Sublandlord and in any event prior to such time as would either (y) subject
Landlord, Sublandlord, Sublandlord’s agents or any mortgagee or ground lessee to civil or criminal liability or prosecution for a crime,
or (z) cause a default under any applicable mortgage or ground lease; or

 

 (ii) if (A) any petition is filed by Subtenant
under any provision of Federal or state bankruptcy laws or other statute whether domestic or foreign involving creditors’ rights or the
insolvency of debtors or any such petition is filed against Subtenant and Subtenant fails to secure a dismissal or stay thereof within
thirty (30) days, or (B) Subtenant shall become insolvent or make an assignment for the benefit of creditors, or (C) a receiver is appointed
for all or substantially all of the assets of Subtenant and Subtenant fails to secure a dismissal or stay thereof within sixty (60) days,
or (D) all or a material portion of the Subleased Premises shall be abandoned, deserted or vacated.

 

    5

     

    

 

(b) Upon
the occurrence of an Event of Default, Sublandlord shall have the right, at its option, to do and perform any one or more of the following,
in addition to, and not in limitation of any other remedy or right permitted it by law, by this Sublease or by the Lease:

 

(i) terminate
this Sublease, in which event Subtenant shall immediately surrender the Subleased Premises to Sublandlord, but if Subtenant shall fail
to do so, Sublandlord may, without prejudice to any other right or remedy Sublandlord may have, either by law or under this Sublease or
otherwise, obtain possession or rent in arrears or damages for breach of contract, enter upon the Subleased Premises and expel or remove
Subtenant and Subtenant’s personal property, with or without force and without being liable to Subtenant, and Subtenant agrees to indemnify
and hold Sublandlord harmless for all losses or damage which Sublandlord may suffer by reason of such termination, whether through inability
to relet the Subleased Premises or through decrease in rent or by damage to the Subleased Premises, or otherwise, or

 

(ii) enter
the Subleased Premises and remove Subtenant and its personal property therefrom without terminating this Sublease or being liable to Subtenant
in any manner whatsoever for such acts, and, at Sublandlord’s option, relet the Subleased Premises as the agent of Subtenant and receive
rent therefor, and in such event Subtenant shall be liable on a monthly basis when rent is otherwise due and payable to Sublandlord for
any deficiency which may arise by reason of such reletting during the remainder of the Term of this Sublease, but shall not be entitled
to any surplus so arising. In the event of a conflict between the provisions of this Paragraph 8 and the provisions of the Lease, the
provisions of this Paragraph 8 shall prevail.

 

9. Subletting
and Assignment.

 

(a) Subtenant
shall not assign, mortgage, pledge, encumber or in any manner transfer this Sublease or any part thereof nor sublet or suffer the Subleased
Premises or any part thereof to be used by others, except as expressly permitted by this Sublease and the Lease. It is understood that
a change in control of Subtenant shall be deemed to constitute an assignment of this Sublease. The provisions of the Lease relating to
assignment and subletting shall be deemed to be incorporated into this Sublease.

 

(b) If
this Sublease is assigned in violation of the provisions of this Sublease, Sublandlord may and is hereby empowered to collect rent from
the assignee. In such event, Sublandlord may apply the net amount received by it to the Fixed Rent, Additional Rent or any other payments
herein reserved or provided for, and no such collection shall be deemed a waiver of the covenant herein against assignment, mortgage,
pledge or encumbrance, or an acceptance of the assignee as a tenant or subtenant under this Sublease or a release of Subtenant from the
further performance of its covenants herein. If the Subleased Premises or any part thereof is sublet or occupied by others in violation
of the provisions of this Sublease, Sublandlord is hereby empowered to collect rent from the subtenant or other occupant, and to apply
the same to the curing of any default hereunder in any order of priority Sublandlord may elect, any unexpended balance to be applied by
Sublandlord against any rental or other obligations subsequently becoming due. The making of any assignment, mortgage, pledge, encumbrance
or subletting in whole or in part, and whether or not in violation of the provisions of this Sublease, shall not operate to relieve Subtenant
from its obligations under this Sublease and, notwithstanding any such assignment, mortgage, pledge, encumbrance or subletting, Subtenant
shall remain liable for the payment of all Fixed Rent, Additional Rent and other charges and for the due performance of all the covenants,
agreements, terms and provisions of this Sublease until the end of the Term. Each and every assignee, whether as assignee or as successor
in interest of Subtenant or as assignee or successor in interest of any assignee, shall immediately be and become and remain liable jointly
and severally with Subtenant and with each other for the payment of the Fixed Rent, Additional Rent and other charges payable under this
Sublease and for the due performance of all the covenants, agreements terms and provisions of this Sublease on the part of Subtenant to
be paid and performed until the end of the Term.

 

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(c) Any
proposal by Subtenant to assign this Sublease or to further sublet the Subleased Premises or any portion thereof shall be subject to the
prior written consent of Landlord and Sublandlord. Sublandlord’s consent to a proposed assignment or subletting of the Subleased
Premises shall be deemed to have been granted provided that Landlord has given its consent therefor. Subtenant shall reimburse Sublandlord
for all reasonable out-of-pocket expenses incurred in connection with a proposed assignment or subletting.

 

10. Liability
Insurance.

 

(a) Neither
Sublandlord nor its successors, assigns, employees or agents shall be liable for any loss of or damage to property of Subtenant or Subtenant’s
subtenants, assigns, employees, agents or visitors, except for loss or damage resulting from Sublandlord’s gross negligence or willful
misconduct. With respect to the Subleased Premises, Sublandlord, its successors, assigns, employees and agents shall not be liable for
any injury or damage to persons or property except for loss or damage resulting from the gross negligence or willful misconduct of Sublandlord,
its successors, assigns, employees and agents.

 

(b) Subtenant
shall maintain with respect to the Subleased Premises comprehensive general public liability insurance, property insurance and other insurance
in the manner and with the minimum limits set forth in the Lease, with insurance companies qualified to do business in the State of New
York and otherwise meeting the standards set forth in the Lease, insuring Subtenant, Sublandlord, Landlord and any other parties required
in accordance with the Lease as named insureds, against, inter alia, claims and liabilities for bodily injury or death to persons, and
damage to property. Each party shall look exclusively to any insurance carried by it pursuant to this Sublease and the Lease for loss
or damage to property resulting from the negligence of the other party or its agents, servants, employees, contractors, invitees or licensees,
and, to the extent permitted by law, Sublandlord and Subtenant each hereby releases and waives all right of recovery against the other
or anyone claiming through or under each of them by way of subrogation or otherwise, provided that such waivers of liability are permitted
and are available under both Sublandlord’s and Subtenant’s policies of insurance or such waivers are approved by their insurance carriers.
Each party agrees to pay the added cost, if any, of obtaining such approval from its insurance carrier. Subtenant shall deliver certificates
of insurance to Sublandlord with respect to all insurance required under this Sublease and the Lease on or before the signing of this
Sublease by Subtenant. Each of Subtenant’s policies of insurance shall provide that such policy may not be materially changed, amended,
canceled or allowed to lapse except upon thirty (30) days’ prior notice to Sublandlord, Landlord and any other parties required in accordance
with the Lease. Such insurance shall be subject to Sublandlord’s approval as to form, content, coverage and expiration dates, which approval
shall be deemed granted if not refused within fifteen (15) days after delivery of the certificates of insurance to Sublandlord.

 

11. Indemnification.
Except as provided in Paragraph 10 hereof, Subtenant shall indemnify and hold harmless Sublandlord from and against all claims, losses,
costs, damages, expenses and liabilities (including, but not limited to, the costs of legal proceedings and reasonable attorneys’ fees
and disbursements) which Sublandlord may incur, pay or have asserted against it by reason of any injuries to persons occurring in, on
or about the Subleased Premises caused by the acts or omissions of Subtenant, its agents, employees, guests or invitees or by reason of
any breach, failure or default hereunder on Subtenant’s part, including any breach or default which results in a breach of or possible
termination or forfeiture of the Lease. In the event of a conflict between the provisions of this Paragraph 11 and any provision of the
Lease, the provisions of this Paragraph 11 shall prevail. The provisions of this Paragraph 11 shall survive the expiration or earlier
termination of this Sublease.

 

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12. Subtenant’s
Rights. Notwithstanding anything to the contrary herein set forth, Subtenant shall in no case have any rights in respect of the Subleased
Premises greater than the rights of Sublandlord under the Lease.

 

13. Possession,
Care and Condition of Subleased Premises.

 

(a) Possession
and Condition. Subtenant acknowledges that it has examined the Subleased Premises and that it is leasing the Subleased Premises in
their “as is” condition. Sublandlord shall have no obligation to perform any work or supply any materials to prepare the Subleased
Premises for Subtenant’s occupancy. Subject to Paragraph 7 above, Subtenant shall, at its sole cost and expense, make any alterations
and improvements that it requires to prepare the Subleased Premises for its occupancy thereof. Sublandlord has made no representation
or warranty concerning the condition of the Subleased Premises except as expressly set forth in this Sublease. Notwithstanding the forgoing,
Sublandlord shall grant to Subtenant a work allowance in the amount of One Hundred Thousand and 00/100 Dollars ($100,000.00) (the “Allowance”)
to be utilized by Subtenant for the hard and soft costs of the work to be done by Subtenant to prepare the Subleased Premises for its
occupancy (“Subtenant’s Work”). Subtenant’s Work shall be deemed to be Subtenant Improvements for purposes of
this Sublease, and the terms and provisions of Paragraph 7 above shall be applicable thereto. Upon completion of Subtenant’s Work,
Subtenant’s shall submit to Sublandlord: (a) copies of bills and receipts indicating that all contractors, sub-contractors and soft
cost providers performing or supporting the performance of Subtenant’s Work have been paid in full, (b) the documents identified
in Section 8.1 (a)(iii), items (iii), (iv) and (v) of the First Amendment and (c) the document identified in Section 8.1 (d), item (x)
of the First Amendment. Within twenty (20) days after submission of the foregoing items and a requisition showing the total amount expended
on Subtenant’s Work, and provided that Subtenant is not then in default under this Sublease, Sublandlord shall pay to Subtenant
the lesser of the amount indicated in Subtenant’s requisition and the amount of the Allowance.

 

(b) Included
Property. Sublandlord shall leave the furniture, fixtures and equipment which are presently situated in the Subleased Premises, and
which are identified in Exhibit “B” which is attached hereto as an integral part hereof (the “Included Property”)
in the Subleased Premises. Subtenant shall take possession of the Included Property in its “as is”, “where is”
condition. Sublandlord makes no representations or warranties with respect to the Included Property. The Included Property shall remain
the property of Sublandlord, and Subtenant shall exercise the care of a prudent custodian in its use and care of the Included Property
during the Term. Notwithstanding the foregoing, if this Sublease has not then been terminated in accordance with the terms hereof, then,
on July 1, 2027 title to the Included Property shall, without any action on the part of the Sublandlord or Subtenant, be transferred to
Subtenant and Subtenant shall thereupon be the owner of the Included Property for all purposes. Thereafter, upon the expiration of the
Term, Subtenant at its sole cost and expense, shall remove the Included Property from the Subleased Premises. If Subtenant shall fail
to remove any of the Included Property, Sublandlord may arrange for such removal and the costs of such removal plus an incremental amount
of fifteen percent (15%) shall be paid to Sublandlord by Subtenant within fifteen (15) days after demand therefor. In addition to the
Included Property, Sublandlord shall leave the existing supplemental air conditioning unit (the “A/C Unit”) which services
the IDF closet in the Subleased Premises for Subtenant’s use. Sublandlord makes no representation as to the condition of the Unit.
It shall be the responsibility of Subtenant to maintain the Unit, to carry a maintenance contract covering the Unit and to replace the
Unit, if necessary.

 

(c) Restoration
of Subleased Premises. On the date upon which the term hereof shall expire and come to an end, whether by expiration, by lapse of
time or otherwise, Subtenant, at its sole cost and expense, shall quit and surrender the Subleased Premises to Sublandlord in good order
and condition and broom clean. Prior to such date, Subtenant, at its sole cost, shall remove all of the Sublease Improvements it (or such
portion thereof as shall be required by Landlord) and otherwise restore the Subleased Premises to its condition on the Commencement Date.

 

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(d) Freight
Elevator. Sublandlord shall pay for or reimburse Subtenant for up to ten (10) hours of overtime freight elevator usage for Subtenant’s
move-in to the Subleased Premises.

 

(e) Holdover.
Notwithstanding anything to the contrary provided elsewhere in this Sublease, if Subtenant holds over in the Subleased Premises after
the Expiration Date, Subtenant shall pay to Sublandlord within five (5) days after demand in each case one hundred twenty five percent
(125%) of all amounts that Sublandlord is required to pay Landlord on account of such holdover. In addition, Subtenant shall be liable
to Sublandlord for all damages (including consequential damages), costs and expenses (including attorneys’ fees and expenses) incurred
by Sublandlord as a consequence of the holdover.

 

(f) Obligation
to Repair. Subtenant shall take good care of the Subleased Premises and the fixtures and appurtenances therein. All damage or injury
to the Subleased Premises and to its fixtures, appurtenances and equipment or to the Building caused by Subtenant’s moving of Subtenant’s
property in or out of the Building or by Subtenant’s installation or removal of furniture, fixtures or other property, or resulting from
Subtenant’s negligent acts, omissions or misconduct shall be promptly repaired by Subtenant, at its sole cost and expense, to the reasonable
satisfaction of Sublandlord and Landlord. If a request is made by Landlord for Sublandlord to make reasonable repairs the Subleased Premises
in accordance with the Lease, Subtenant shall undertake such repair at its cost in accordance with the Lease. All of said repairs required
to be made by Subtenant shall be in quality and class equal to the original work or installation and shall be done in a good and workmanlike
manner. If Subtenant fails to make such repairs, the same may be made by Sublandlord or Landlord at the expense of Subtenant and all sums
so spent and expenses incurred by Sublandlord plus an incremental amount of fifteen percent (15%) of such sums shall be collectible as
Additional Rent and shall be paid by Subtenant to Sublandlord within five (5) days after rendition of a bill or statement therefor.

 

14. Notices.
Notices, demands and any other communications hereunder shall be in writing and shall be given or made by personal delivery, by overnight
delivery by a recognized national courier service or by certified mail, return receipt requested, addressed to the parties at the addresses
hereinabove set forth (and, in the case of Sublandlord, addressed to the attention of its Chief Operating Officer with a copy addressed
to the attention of its General Counsel), or such other address which either party may hereafter designate for such purpose by a written
notice. Notices, demands and other communications shall be deemed given (a) if delivered by personal delivery or by overnight courier
service, on the date of delivery or rejection of delivery, or (b) if sent by certified mail, upon receipt or rejection of such delivery.
Sublandlord shall, within five (5) days after receipt thereof, give to Subtenant a copy of each notice or demand received from Landlord
relating to the Subleased Premises, and Subtenant shall, within five (5) days after receipt thereof, give to Sublandlord a copy of each
notice or demand received from Landlord relating to the Subleased Premises.

 

15. Miscellaneous.
This Sublease contains the entire agreement of the parties with respect to the transactions contemplated hereby, supersedes all prior
agreements or understandings between the parties (except as otherwise provided herein) and may not be changed or modified in any way unless
such change or modification is in writing and signed by the parties hereto. Neither Sublandlord nor Subtenant has made any representations
or warranties with respect to this Sublease except as set forth herein. If any provision of this Sublease shall be held to be invalid
or unenforceable in any respect, the validity or enforceability of the remaining portions of this Sublease shall be unaffected thereby.
This Sublease shall be binding upon, inure to the benefit of and be enforceable by the parties hereto and their respective successors
and assigns. The headings in this Sublease are for convenience only and shall not be used in construing the intentions of the parties.
This Sublease shall be governed by and construed in accordance with the laws of the State of New York. Sublandlord and Subtenant each
represents that it has full right and authority to enter into this Sublease and that the officer signing this Sublease on its behalf is
authorized to do so. This Sublease may be signed in counterparts, each of which shall constitute an original but all of which, when taken
together, shall constitute one instrument. Faxed signatures, emailed copies of signatures and signatures exchanged via PDF or other electronic
means shall be binding to the same extent as original signatures. Sublandlord and Subtenant each waives, to the extent permitted by law,
the right to a jury trial in any action or legal proceeding between the parties arising out of this Sublease or Subtenant’s occupancy
of the Subleased Premises.

 

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16. Attorneys’
Fees. If either party hereto is made or becomes a party to any litigation commenced by or against the other party involving the enforcement
of any of the rights and remedies of such party, or arising on account of the default of the other party in the performance of such party’s
obligations hereunder, then the prevailing party in such litigation, or the party becoming involved in such litigation because of a claim
against such other party, as the case may be, shall be reimbursed by the other party for all costs and reasonable attorneys’ fees incurred
by such party in such litigation.

 

17. Interest;
Late Charges. Subtenant shall, on demand, pay interest on any Fixed Rent, Additional Rent and other amounts payable by Subtenant to
Sublandlord pursuant hereto if any such amount is received after its due date. Interest for each calendar month or portion thereof shall
be at the rate of one and one-half percent (11⁄2%) of the overdue amount (but in no event in excess of the maximum rate permitted
by law). In addition, if any Fixed Rent, Additional Rent or other amount payable by Subtenant to Sublandlord pursuant hereto is not paid
within ten (10) days after its due date, Subtenant shall pay to Sublandlord a late charge of five cents ($.05) for each Dollar of the
overdue amount to defray Sublandlord’s administrative costs for handling the late payment. The right of Sublandlord to collect interest
and late charges shall be without derogation of any other right of Sublandlord hereunder, the amounts payable under this Paragraph 17
shall be deemed to be Additional Rent for purposes of this Sublease.

 

18. Brokerage.
Sublandlord and Subtenant each represents and warrants to the other that it has had no dealings or communications with any broker or agent
in connection with this Sublease other than Jones Lang LaSalle Brokerage, Inc. and Lee & Associates (the “Brokers”). In
the event any broker or agent other than the Brokers claims that it is entitled to a commission due to the acts of Sublandlord or Subtenant,
such party covenants and agrees to pay, hold harmless and indemnify the other party from and against any and all costs, expenses or liability
incurred by the other party in connection with or relating to any claims for compensation, commissions and fees asserted by such broker
or agent with respect to this Sublease or the negotiation hereof (including, without limitation, the cost of legal fees and related expenses
incurred in connection with defending against such claims). Sublandlord agrees to pay the commissions owing to the Brokers pursuant to
a separate agreement or agreements.

 

19. Security.

 

(a) As
security for the full and punctual performance by Subtenant of all of the terms and conditions of this Sublease, Subtenant shall submit
to Sublandlord on or before the date that it signs this Sublease and shall maintain throughout the term of this Sublease a security deposit
in the amount of Two Hundred Ninety Nine Thousand Four Hundred Forty Seven and 50/100 Dollars ($299,447.50) (the “Security Deposit”).
The Security Deposit shall take the form of an irrevocable standby letter of credit in form and substance satisfactory to Sublandlord
(the “Letter of Credit”) issued by a commercial bank which is a member of the New York Clearing House Association or another
commercial bank which is acceptable to Sublandlord and shall have an initial term which is not less than one (1) year from its date of
issuance. The Letter of Credit shall provide that Sublandlord may draw thereunder by the submission of only a sight draft and, unless
otherwise agreed by Sublandlord, shall permit Sublandlord to make presentment thereunder at an office of the bank located in the City
of New York. In each case, the Letter of Credit shall further provide that Sublandlord may draw the full amount thereof if it is not extended
for an additional one (1) year period at least forty five (45) days prior to its stated expiration date. The final Letter of Credit issued
hereunder shall have an expiration date which is no early than ninety (90) days after the Expiration Date. Each Letter of Credit shall
be in form and substance fully satisfactory to Sublandlord.

 

(b) Whenever
Subtenant is in default under this Sublease and such default has continued after any applicable written notice has been delivered to Subtenant
and beyond any applicable cure period or whenever Sublandlord has obtained a judgment against Subtenant based on a claim arising out of
this Sublease, Sublandlord may draw the amount of such default or judgment, as the case may be, from the Security Deposit, to the extent
required for the payment of any Fixed Rent or Additional Rent or for any sum which Sublandlord may expend or be required to expend by
reason of Subtenant’s default.

 

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(c) In
the case of every use, application or retention of the Security Deposit, Subtenant shall, within three (3) days after demand, replenish
the Security Deposit to the amount which Subtenant is required to maintain hereunder and the failure to do so shall constitute an Event
of Default hereunder without any notice or cure period.

 

(d) In
lieu of the Letter of Credit, Subtenant shall have the option of submitting the Security Deposit in cash on or before the date that it
signs this Sublease; provided, however, that, in such case, Subtenant shall substitute a Letter of Credit which meets the requirements
of Paragraph 19(a) above for the cash Security Deposit within sixty (60) days after the date of this Sublease and the failure of Subtenant
to do so shall constitute an Event of Default hereunder without any notice or cure period. Sublandlord shall return the cash Security
Deposit to Subtenant immediately after its receipt of the Letter of Credit.

 

20. Consent
to Jurisdiction. Each of the parties hereto hereby irrevocably consents and agrees that any legal action or proceeding with respect
to this Sublease may be brought in any of the Federal or state courts having subject matter jurisdiction located in the Borough of Manhattan,
The City of New York, and, by its execution and delivery of this Sublease, each such party hereby (a) accepts the non-exclusive jurisdiction
of the aforesaid courts, (b) irrevocably agrees to be bound by any final judgment (after any appeal) of any such court with respect to
this Sublease, and (c) irrevocably waives, to the fullest extent permitted by law, any objection which it may now or hereafter have to
the laying of venue of any suit, action or proceeding with respect to this Sublease brought in any such court, and further irrevocably
waives, to the fullest extent permitted by law, any claim that any such suit, action or proceeding brought in any such court has been
brought in an inconvenient forum.

 

21. Representations
and Warranties. Sublandlord hereby represents and warrants to Subtenant that, as of this date, Sublandlord has not received from Landlord
or given to Landlord any notice of a default under the Lease and, to the best of its knowledge, no default under the Lease currently exists.
Further, Sublandlord represents and warrants to Subtenant that, as of this date, the Lease is in full force and effect.

 

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IN WITNESS WHEREOF, this Sublease has been executed
by the duly authorized representatives of the parties as of the day and year first above written.

 

	 	SUBLANDLORD:
	 	 
	 	ABN AMRO HOLDING USA LLC
	 	 
	 	By:	                        
	 	 	Name:
	 	 	Title:
	 	 
	 	SUBTENANT:
	 	 
	 	ACTINIUM PHARMACEUTICALS, INC.
	 	 
	 	By:	        
	 	 	Name:
	 	 	Title:

 

     

     

    

 

SUBTENANT ACKNOWLEDGEMENT

 

	STATE OF NEW YORK	)	 
	 	)	ss.:
	COUNTY OF-NEW YORK 	)	 

 

On the __ day of _____________, 2022, before me,
the undersigned, a Notary Public in and for said state, personally appeared ___________________________ who proved to me on the basis
of satisfactory evidence to be the individual whose name is subscribed to the within instrument and acknowledged to me that he (she) executed
the same in his (her) capacity , and that by his (her) signature on the instrument, the individual, or the person upon behalf of which
the individual acted, executed the instrument.

 

	 	 
	 	Notary Public

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