Document:

Letter Agreement

 Exhibit 10.1 
  
 [Essential Group, Inc. Letterhead] 
  

December 7, 2004 
  
 Pradip K. Banerjee, Ph.D. 
 141 Christopher Drive 
 Princeton, NJ 08540 
  
 Dear Pradip: 

 
 We are pleased to confirm our offer to you of the position of Chairman of the Board of
Essential Group, Inc. (the “Company”). Your appointment to such position will be effective October 28, 2004 and your services as Chairman will be in addition to your services as a member of the Board of Directors of the Company.

  
 The Company greatly values the leadership, knowledge and experience that you
will bring to this role. The entire Board of Directors and the management team look forward to our working relationship and appreciate your involvement in the Company’s mission. 
  
 As consideration for your services as Chairman, the Company will pay you an annual retainer of $20,000 per year, payable in arrears and in
equal quarterly installments of $5,000. Separate to such cash compensation, you will receive a one-time grant of options to purchase up to 25,000 shares of the Company’s Class A Common Stock, $0.001 par value per share (“Common
Stock”), at the fair market value of those shares on the date of issue. In addition, as a member of the Board of Directors, you will also be granted annually stock options as follows: options to purchase up to 1,000 shares of Common Stock for
each quarterly Board meeting that you attend, options to purchase up to 1,000 shares of Common Stock for each Board subcommittee of which you are a member, options to purchase up to 1,000 shares of Common Stock for each Board subcommittee on which
you serve as Chairperson, and options to purchase up to 1,000 shares of Common Stock for serving as Chairman. The grants of options described in this paragraph are subject to Board approval and the terms and conditions of any options granted to you
as consideration for your services as Chairman and as a member of the Board of Directors will be governed by the Company’s Amended and Restated 1996 Director Stock Option Plan. 
  
 In addition to and separate from your roles as Chairman and as a member of the Board of Directors of the Company, you have agreed to devote
up to 15% of your business time monthly serving as an independent consultant to management on the Company’s business for the period September 1, 2004 through December 31, 2005. 
  
 As consideration for your consulting services, in the event of a Corporate Transaction (as defined below) and unless the Consultant Options
(as defined below) have become exercisable, you will have the right to receive, subject to vesting, adjustment and termination as described below, a transaction bonus equal to one and one half percent (1.5%) (the “Transaction Bonus
Percentage”) of the amount that the holders of the Series A-1 through Series A-7 Preferred Stock of the Company would have received on account of such holders’ right to receive a liquidation preference related to the shares of Series
A-1 through Series A-7 Preferred Stock of the Company held by such holders in connection with such Corporate Transaction but for any amounts payable pursuant to this agreement and any amounts payable in connection with such Corporate Transaction
pursuant to the Company’s Management Alignment Pool (the “Transaction Bonus”). The Transaction Bonus will be calculated and payable to you immediately prior to the consummation of a Corporate Transaction. 

 Pradip K. Banerjee, Ph.D. 
 December 7, 2004 
 Page 2 
  
 A “Corporate Transaction” shall mean the consummation of (A) a reorganization, merger or consolidation or (B) a sale, transfer or other disposition
(including the liquidation) of all or substantially all of the Company’s assets (each, a “Business Combination”), unless, in each case, immediately following such Business Combination, all or substantially all of the
individuals and entities who were the beneficial owners of securities entitled to vote generally in the election of directors of the Company immediately prior to such Business Combination beneficially own, directly or indirectly, more than 50% of
the then outstanding shares of common stock and the combined voting power of the then outstanding voting securities entitled to vote generally in the election of directors of the entity resulting from such Business Combination (whether such entity
is the Company or another entity) in substantially the same proportions relative to each other as their ownership, immediately prior to such Business Combination, of the securities entitled to vote generally in the election of directors of the
Company. A Corporate Transaction shall not include an IPO (as defined below). 
  
 The Transaction Bonus Percentage will vest at a rate of 0.3% per quarter beginning with the quarter ending December 31, 2004 and ending on the quarter ending December 31, 2005, at which time the 1.5% will be fully vested. In the event you
cease serving as a consultant to the Company for any reason prior to December 31, 2005, the vesting of your Transaction Bonus Percentage will continue through the calendar quarter end for the quarterly period in which your services were terminated.

  
 In addition, within twenty (20) business days of your acceptance of this
agreement, the Company will grant to you, subject to Board approval, options (the “Consultant Options”) to purchase up to 150,000 shares of Common Stock under a consultant stock option plan (the “Plan”), which
Consultant Options will vest and become exercisable only as described below. Unless you have previously received a Transaction Bonus and provided that you are continuing to serve or have completed your service as an independent consultant to
management of the Company pursuant to the terms of this agreement, upon the consummation of a firm commitment underwritten public offering pursuant to an effective registration statement under the Securities Act of 1933, as amended, covering the
offer and sale of any of the Company’s capital stock for the account of the Company (such transaction, an “IPO”), (A) your right to receive the Transaction Bonus will terminate and (B) the Consultant Options will vest and
become exercisable at a price per share of $1.25, payable in accordance with the terms of the Plan. Notwithstanding the above, upon the payment of a Transaction Bonus attributable to the consummation of a Corporate Transaction prior to the
consummation of an IPO, the Consultant Options will terminate and be of no effect. 
  
 The calculation of the amount of any payment to be made pursuant to the Transaction Bonus is based on the Company’s assumption that you will devote up to 15% of your business time as a consultant to management. Notwithstanding anything
to the contrary herein, in the event that you devote less than such percentage of your business time as a consultant to management, any payment to be made pursuant to the Transaction Bonus will be ratably reduced. 

 Pradip K. Banerjee, Ph.D. 
 December 7, 2004 
 Page 3 
  
 Nothing herein is intended to imply an obligation on the part of the Company to continue to utilize your consulting services after December 31, 2005. It is understood,
agreed and acknowledged that you will provide services as an independent consultant and that no employment relationship will exist between you and the Company as a result of your provision of such services. 
  
 Again, we are extremely excited about the strength you’ll bring as Chairman and look
forward to working with you. 
  

	Sincerely,	

  

	
	 /s/ C. Lee Jones

	 C. Lee Jones

	 President & CEO

  
 ACCEPTED AND AGREED: 
  

	
	 /s/ Pradip K. Banerjee

	 Pradip K. Banerjee

	 Date: December 10, 2004Description of Executive Officer Cash Bonus Program

 Exhibit 10.1 
  
 MAXYGEN INC. 
  
 DESCRIPTION OF EXECUTIVE OFFICER CASH
BONUS PROGRAM 
  
 Maxygen maintains
an Executive Officer Cash Bonus Program for executive officers that is designed to reward participants based on their individual performance and the company’s financial and other performance. The program provides for an annual bonus based upon
the company’s attainment of annual financial and other performance targets as well as subjective factors related to the individual participant’s employment performance. The annual financial and other targets for the program are set by the
Compensation Committee of Maxygen’s Board of Directors and are currently based on the company’s financial performance (revenue and cash burn), product development goals and other objectives. 
  
 Executive officers (including the CEO) are eligible to receive annual cash
performance bonuses of between 0 and 50% of base salary. The target bonus amount for the company’s executive officers is 25% of base salary. Bonus payments are paid in one annual payment shortly after the end of each calendar year.Certificate for Common Stock

 Exhibit 4.1 
  
 NUMBER 
 DRT 
 COMMON STOCK 
 PAR VALUE $0.01 
 THIS CERTIFICATE IS TRANSFERABLE IN NEW YORK, NY 
 [LOGO] 
 CUSIP 253868 10    3 
 SEE REVERSE FOR CERTAIN
RESTRICTIONS 
 DIGITAL REALTY TRUST, INC. 
 INCORPORATED UNDER
THE LAWS OF THE STATE OF MARYLAND 
 THIS CERTIFIES THAT 
 IS THE
OWNER OF 
  
 FULLY-PAID AND NON-ASSESSABLE COMMON STOCK, PAR VALUE $0.01 PER SHARE
OF DIGITAL REALTY TRUST, INC. (the “Corporation”) transferable on the books of the Corporation by the holder hereof in person or by its duly authorized attorney, upon surrender of this Certificate properly endorsed. This Certificate and
the shares represented hereby are issued and shall be held subject to all of the provisions of the Articles of Amendment and Restatement of the Corporation (the “Charter”) and the Bylaws of the Corporation and any amendments thereto. This
Certificate is not valid unless countersigned and registered by the Transfer Agent and Registrar. 
  
 In Witness Whereof, the Corporation has caused this Certificate to be executed on its behalf by its duly authorized officers. 
  
 Dated: 
  

			
	
	 COUNTERSIGNED AND REGISTERED:
  

	 AMERICAN STOCK TRANSFER & TRUST COMPANY

	 (NEW YORK, NY) TRANSFER AGENT

	 AND REGISTRAR

		
	 BY
	 	  

	 	 	 AUTHORIZED SIGNATURE

		
	 	 	 [SEAL]

		
	 	 	 /s/

	 	 	 MICHAEL F. FOUST

	 	 	 CHIEF EXECUTIVE OFFICER AND SECRETARY

		
	 	 	 /s/

	 	 	 A. WILLIAM STEIN

	 	 	 CHIEF FINANCIAL OFFICER

  
 DIGITAL REALTY TRUST, INC. 
  
 THE SHARES OF COMMON STOCK REPRESENTED BY
THIS CERTIFICATE ARE SUBJECT TO RESTRICTIONS ON BENEFICIAL AND CONSTRUCTIVE OWNERSHIP AND TRANSFER FOR THE PURPOSE OF THE CORPORATION’S MAINTENANCE OF ITS STATUS AS A REAL ESTATE INVESTMENT TRUST (“REIT”) UNDER THE INTERNAL REVENUE
CODE OF 1986, AS AMENDED (THE “CODE”). SUBJECT TO CERTAIN FURTHER RESTRICTIONS AND EXCEPT AS EXPRESSLY PROVIDED IN THE CORPORATION’S ARTICLES OF AMENDMENT AND RESTATEMENT, (I) NO PERSON MAY BENEFICIALLY OR CONSTRUCTIVELY OWN SHARES OF
CAPITAL STOCK OF THE CORPORATION IN EXCESS OF 9.8% OF THE VALUE OF THE TOTAL OUTSTANDING SHARES OF CAPITAL STOCK OF THE CORPORATION AND NO PERSON MAY BENEFICIALLY OR CONSTRUCTIVELY OWN SHARES OF THE CORPORATION’S COMMON STOCK IN EXCESS OF 9.8%
(BY VALUE OR BY NUMBER OF SHARES, WHICHEVER IS MORE RESTRICTIVE) OF THE OUTSTANDING COMMON STOCK OF THE CORPORATION; (II) NO PERSON MAY BENEFICIALLY OR CONSTRUCTIVELY OWN SHARES OF CAPITAL STOCK THAT WOULD RESULT IN THE CORPORATION BEING
“CLOSELY HELD” UNDER SECTION 856(h) OF THE CODE OR OTHERWISE CAUSE THE CORPORATION TO FAIL TO QUALIFY AS A REIT; AND (III) NO PERSON MAY TRANSFER SHARES OF CAPITAL STOCK IF SUCH TRANSFER WOULD RESULT IN THE CAPITAL STOCK OF THE CORPORATION
BEING OWNED BY FEWER THAN 100 PERSONS. ANY PERSON WHO 

 BENEFICIALLY OR CONSTRUCTIVELY OWNS OR ATTEMPTS TO BENEFICIALLY OR CONSTRUCTIVELY OWN SHARES OF CAPITAL STOCK IN
VIOLATION OF THE ABOVE LIMITATIONS MUST IMMEDIATELY NOTIFY THE CORPORATION. IF ANY OF THE RESTRICTIONS ON TRANSFER OR OWNERSHIP SET FORTH IN (I) OR (II) IS VIOLATED, THE SHARES OF COMMON STOCK REPRESENTED HEREBY WILL BE AUTOMATICALLY TRANSFERRED TO
THE TRUSTEE OF A TRUST FOR THE BENEFIT OF ONE OR MORE CHARITABLE BENEFICIARIES, AND ANY TRANSFER THAT WOULD RESULT IN THE CAPITAL STOCK OF THE CORPORATION BEING OWNED BY FEWER THAN 100 PERSONS SHALL BE VOID AB INITIO. IN ADDITION, THE CORPORATION
MAY REDEEM SHARES UPON THE TERMS AND CONDITIONS SPECIFIED BY THE BOARD OF DIRECTORS IN ITS SOLE DISCRETION IF THE BOARD OF DIRECTORS DETERMINES THAT OWNERSHIP OR A TRANSFER OR OTHER EVENT MAY VIOLATE THE RESTRICTIONS DESCRIBED ABOVE. FURTHERMORE,
UPON THE OCCURRENCE OF CERTAIN EVENTS, ATTEMPTED TRANSFERS IN VIOLATION OF THE RESTRICTIONS DESCRIBED ABOVE MAY BE VOID AB INITIO. ALL TERMS IN THIS LEGEND THAT ARE DEFINED IN THE CHARTER OF THE CORPORATION SHALL HAVE THE MEANINGS ASCRIBED TO THEM
IN THE CHARTER OF THE CORPORATION, AS THE SAME MAY BE AMENDED FROM TIME TO TIME, A COPY OF WHICH, INCLUDING THE RESTRICTIONS ON TRANSFER AND OWNERSHIP, WILL BE FURNISHED TO EACH HOLDER OF SHARES OF COMMON STOCK ON REQUEST AND WITHOUT CHARGE.
REQUESTS FOR SUCH A COPY MAY BE DIRECTED TO THE SECRETARY OF THE CORPORATION AT ITS PRINCIPAL OFFICE. 
  
 The Corporation will furnish to any stockholder, on request and without charge, a full statement of the information required by Section 2-211(b) of the Corporations and Associations Article of the Annotated Code of
Maryland with respect to the designations and any preferences, conversion and other rights, voting powers, restrictions, limitations as to dividends and other distributions, qualifications, and terms and conditions of redemption of the stock of each
class which the Corporation has authority to issue and, if the Corporation is authorized to issue any preferred or special class in series, (i) the differences in the relative rights and preferences between the shares of each series to the extent
set, and (ii) the authority of the Board of Directors to set such rights and preferences of subsequent series. The foregoing summary does not purport to be complete and is subject to and qualified in its entirety by reference to the charter of the
Corporation, a copy of which will be sent without charge to each stockholder who so requests. Such requests must be made to the Secretary of the Corporation at its principal office or to the Transfer Agent. 
  
 TEN COM – as tenants in common 
 TEN ENT – as tenants by the entireties 
 JT TEN – as joint tenants
with right of survivorship and not as tenants in common 
 UNIF GIFT/TRANS MIN ACT – (Cust) Custodian (Minor) under Uniform Gifts/Transfers to Minors Act
(State) 
 Additional abbreviations may also be used though not in the above list. 
 FOR VALUE RECEIVED, HEREBY SELL, ASSIGN AND TRANSFER UNTO 
 PLEASE INSERT SOCIAL SECURITY OR OTHER IDENTIFYING NUMBER OF
ASSIGNEE 
 (Please Print or Typewrite Name and Address, Including Zip Code, of Assignee) 
 shares of the shares represented by the within Certificate, and do hereby irrevocably constitute and appoint 
 Attorney to
transfer the said shares on the books of the within named Corporation with full power of substitution in the premises. 
  
 Dated 
  
 NOTICE: The Signature To This Assignment Must Correspond With The Name As Written Upon The Face Of The Certificate In Every Particular, Without Alteration Or Enlargement Or Any Change Whatever. 
  
 SIGNATURE(S) GUARANTEED: 
  
 THE SIGNATURE(S) MUST BE GUARANTEED BY AN ELIGIBLE GUARANTOR INSTITUTION (BANKS, STOCKBROKERS, SAVINGS AND LOAN ASSOCIATIONS AND CREDIT
UNIONS WITH MEMBERSHIP IN AN APPROVED SIGNATURE GUARANTEE MEDALLION PROGRAM), PURSUANT TO S.E.C. RULE 17Ad-15. 

 KEEP THIS CERTIFICATE IN A SAFE PLACE. IF IT IS LOST, STOLEN, MUTILATED OR DESTROYED, THE CORPORATION WILL REQUIRE A BOND
OF INDEMNITY AS A CONDITION TO THE ISSUANCE OF A REPLACEMENT CERTIFICATE.

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