Document:

EX-10.1

 Exhibit 10.1 

EMPLOYMENT AGREEMENT 

This Employment Agreement (the “Agreement”) is made between Radius Health, Inc. (the “Company”) and G. Kelly
Martin (the “Executive”). 
 WHEREAS, the Company desires to employ the Executive and the Executive desires to be employed
by the Company beginning on April 28, 2020 (the “Effective Date”) on the terms contained herein. 
 NOW, THEREFORE,
in consideration of the mutual covenants and agreements herein contained and other good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged, the parties agree as follows: 

1.    Employment. 

(a)    Term. The Company shall employ the Executive and the Executive shall be employed by the Company pursuant to
this Agreement commencing as of the Effective Date and continuing until such employment is terminated in accordance with the provisions hereof (the “Term”). The Executive’s employment with the Company shall be “at
will,” meaning that the Executive’s employment may be terminated by the Company or the Executive at any time and for any reason subject to the terms of this Agreement. 

(b)    Position and Duties. 

(i) The Executive shall serve as the Chief Executive Officer and President of the Company (the “CEO”) and shall have such
powers and duties as may from time to time be prescribed by the Board of Directors of the Company (the “Board”). In addition, the Company shall cause the Executive to be nominated for election to the Board and to be recommended to
the stockholders for election to the Board as long as the Executive remains the CEO; provided that the Executive shall not receive additional compensation in connection with his Board service; provided further that the Executive shall
be deemed to have resigned from the Board and from any related positions upon ceasing to serve as CEO for any reason. 
 (ii) Except as
provided in (iii) below, the Executive shall devote the Executive’s full working time and efforts to the business and affairs of the Company. Notwithstanding the foregoing, the Executive will be permitted to (a) with the prior written
consent of the Board, act or serve as a director, trustee, committee member or principal of any type of business that does not compete with the Company, civic or charitable organization, and (b) purchase or own less than five percent (5%) of
the publicly traded securities of any corporation; provided that such ownership represents a passive investment and that the Executive is not a controlling person of, or a member of a group that controls, such corporation; provided
further that, the activities described in clauses (a) and (b) do not interfere with the performance of the Executive’s duties and responsibilities to the Company. 

 (iii) The Company acknowledges that it has been fully advised of the
Executive’s current and contemplated outside business activities and share ownerships in the companies listed on Exhibit A hereto (the “Outside Activities”) and agrees that the restrictions of Subparagraph (ii) do
not apply to those outside activities, provided that such outside activities do not unduly interfere with the performance of the Executive’s duties and responsibilities to the Company. 

(c)    Place of Performance. The principal place of the Executive’s employment shall be the Company’s
principal executive office, which is currently located in Waltham, Massachusetts, provided that the Executive may be required to travel on Company business, consistent with Company business needs. 

2.    Compensation and Related Matters. 

(a)    Base Salary. The Executive’s initial base salary shall be paid at the rate of $600,000 per year. The
Executive’s base salary shall be subject to periodic review and possible increase (but not, without the advance written consent of the Executive, decrease) by the Board or the Compensation Committee of the Board (the
“Compensation Committee”). The base salary in effect at any given time is referred to herein as “Base Salary.” The Base Salary shall be payable in a manner that is consistent with the Company’s usual payroll
practices for its executive officers. 
 (b)    Expenses. The Executive shall be entitled to receive prompt
reimbursement for all reasonable expenses incurred by the Executive during the Term in performing services hereunder, in accordance with the policies and procedures then in effect and established by the Company for its executive officers. 

(c)    Other Benefits. The Executive shall be eligible to participate in or receive benefits under the
Company’s employee benefit plans in effect from time to time, subject to the terms of such plans. The Company reserves the right to amend or cancel any employee benefit plans at any time in its sole discretion, subject to the terms of such
employee benefit plan and applicable law. 
 (d)    Paid Time Off. The Executive shall be entitled to take paid
time off in accordance with the Company’s applicable paid time off policy for executive officers, as may be in effect from time to time. 

(e)    Equity. In consideration of the Executive entering into this Agreement and as an inducement to join the
Company, the Company shall grant to the Executive on the Effective Date (i) 575,000 stock options for the purchase of common stock of the Company that shall be subject to time-based vesting (the “Time-Based Options”), and (ii)
575,000 stock options for the purchase of common stock of the Company, that shall be subject to performance-based vesting (the “Performance-Based Options”). The Time-Based Options and the Performance-Based Options shall have an
exercise price equal to the market price of the Company’s common stock on the Effective Date (which shall also be the date of the grant) and shall have a ten (10) year term prior to expiration. The Time-Based Options will vest over four
(4) years, with 25% of the underlying shares vesting on the first anniversary of the Effective 

  
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Date, and the remaining 75% vesting in equal monthly installments over the following thirty-six (36) months, provided in all cases that the
Executive remains employed in good standing on each such vesting date, except as otherwise provided in this Agreement. The Performance-Based Options shall have a five (5) year performance vesting period (the “Performance Vesting
Period”), with the percentage of the options vesting during such five year period tied to the Company’s achievement of minimum Total Shareholder Return (“TSR”), as defined below, pursuant to the following terms (with
no partial vesting for meeting less than any specified TSR performance-level): 
  

	 	•	 	 If TSR is 50% above the Exercise Price during the Performance Vesting Period for twenty (20) consecutive
trading days, then 25% of the Performance-Based Options shall vest. 

  

	 	•	 	 If TSR is 100% above the Exercise Price during the Performance Vesting Period for twenty (20) consecutive
trading days, then an additional 25% of the Performance-Based Options shall vest (such that a total of 50% of the Performance-Based Options shall be vested). 

  

	 	•	 	 If TSR is 150% above the Exercise Price during the Performance Vesting Period for twenty (20) consecutive
trading days, then an additional 25% of the Performance-Based Options shall vest (such that a total of 75% of the Performance-Based Options shall be vested). 

  

	 	•	 	 If TSR is 200% above the Exercise Price during the Performance Vesting Period for twenty (20) consecutive
trading days, then an additional 25% of the Performance-Based Options shall vest (such that a total of 100% of the Performance-Based Options shall be vested). 

For purposes of the Performance-Based Options, “TSR” means the Company’s total shareholder return, calculated based on the
stock price appreciation during a specified measurement period plus the value of dividends or cash or property paid on such stock during the measurement period which shall be deemed to have been reinvested in the underlying Company’s stock and
subject to appropriate adjustment in the event of any stock dividend, stock split, combination or other similar recapitalization with respect to the shares of common stock of the Company. 

Notwithstanding the foregoing, no Performance-Based Options shall vest prior to the one year anniversary of the grant date, such that if the
Executive achieves any of the above performance criteria prior to the one year anniversary of the grant date, the corresponding vesting shall occur on the one year anniversary of the grant date. 

In addition, notwithstanding the foregoing or anything to the contrary in the applicable option agreement, the Performance-Based Options shall
vest and become fully exercisable in accordance with the TSR performance-level achieved at the time of a Change of Control, as defined below, without regard to either such one year minimum vesting period or the
20-day measurement period described immediately above, and any portion of a Performance-Based Option that does not achieve the required TSR performance-level in connection with such

  
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Change of Control shall immediately be terminated upon the consummation of such transaction, unless the Company or the successor to or acquiror of the Company’s business (whether by sale of
outstanding stock, merger, sale of substantially all the assets or otherwise) elects to assume such unvested outstanding stock options or the common stock of the Company otherwise remains outstanding following the consummation of the Change in
Control. 
 The Time-Based Options and the Performance-Based Options are intended to constitute an “employment inducement grant”
under NASDAQ Listing Rule 5635(c)(4), and consequently are intended to be exempt from the NASDAQ rules regarding shareholder approval of stock option and stock purchase plans. The Time-Based Options and the Performance-Based Options shall be subject
to all terms, vesting schedules, limitations, restrictions and termination provisions set forth in the Company’s 2018 Stock Option and Incentive Plan and form of non-qualified stock option agreement
thereunder, provided that the stock option agreement to be executed by the Executive and the Company to evidence the grant of the Time-Based Options and the Performance-Based Options will reflect that they are being issued as employment
inducement grants outside of the Company’s 2018 Stock Option and Incentive Plan. 
 Upon exercise of the stock options contemplated by
this Agreement, the Executive shall have the right to instruct the Company to deliver to him fewer shares and use the value of the shares not delivered to satisfy the exercise price and meet any payment or employee withholding tax obligations
resulting from the exercise, all as set forth more fully in the stock option agreement to be executed by the Executive and the Company to evidence the grant of the Time-Based Options and the Performance-Based Options. 

(f)    Additional Discretionary Compensation. While the Compensation Committee has discretion to award the
Executive additional incentive compensation from time to time, no annual cash bonus is currently anticipated to be made during the Term, nor are any annual equity refresh grants or other supplemental equity grants anticipated to be made to the
Executive while the Time-Based Options remain subject to vesting. 
 3.    Termination. The Executive’s
employment hereunder may be terminated without any breach of this Agreement under the following circumstances: 

(a)    Death. The Executive’s employment hereunder shall terminate upon death. 

(b)    Disability. The Company may terminate the Executive’s employment if the Executive is disabled and
unable to perform or expected to be unable to perform the essential functions of the Executive’s then existing position or positions under this Agreement with reasonable accommodation for a period of 180 days (which need not be consecutive) in
any twelve (12)-month period. If any question shall arise as to whether during any period the Executive is disabled so as to be unable to perform the essential functions of the Executive’s then existing position or positions with reasonable
accommodation, the Executive may, and at the request of the Company shall, submit to the Company a certification in reasonable detail by a physician selected by the Company to whom the Executive or the Executive’s guardian has no reasonable
objection as to whether the Executive is so disabled or how long such disability is expected to continue, and such certification shall for the purposes of this Agreement be 

  
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conclusive of the issue. The Executive shall cooperate with any reasonable request of the physician in connection with such certification. If such question shall arise and the Executive shall
fail to submit such certification, the Company’s determination of such issue shall be binding on the Executive. Nothing in this Section 3(b) shall be construed to waive the Executive’s rights, if any, under existing law including,
without limitation, the Family and Medical Leave Act of 1993, 29 U.S.C. §2601 et seq. and the Americans with Disabilities Act, 42 U.S.C. §12101 et seq. 

(c)    Termination by Company for Cause. The Company may terminate the Executive’s employment hereunder for
Cause. For purposes of this Agreement, “Cause” shall mean any of the following: 

(i)    the Executive’s commission of an act of fraud, embezzlement or theft against the Company or its
subsidiaries; 
 (ii)    the Executive’s conviction of, or plea of no contest to, a felony or crime
involving moral turpitude; 
 (iii)    the Executive’s willful
non-performance of material duties as an employee of the Company, which to the extent such failure can be fully cured remains uncured for thirty (30) days following the Executive’s receipt of written
notice thereof; 
 (iv)    the Executive’s material breach of any material agreement with the
Company or any of its subsidiaries, including the Restrictive Covenants Agreement (as defined below); 

(v)    the Executive’s gross negligence, willful misconduct or any other act of willful disregard for
the Company’s or any of its subsidiaries’ best interests; or 
 (vi)    the Executive’s
unlawful use (including being under the influence) or possession of illegal drugs on the Company’s (or any of its affiliate’s) premises. 

(d)    Termination by the Company without Cause. The Company may terminate the Executive’s employment
hereunder at any time without Cause. Any termination by the Company of the Executive’s employment under this Agreement which does not constitute a termination for Cause under Section 3(c) and does not result from the death or disability of
the Executive under Section 3(a) or (b) shall be deemed a termination without Cause. 
 (e)    Termination
by the Executive. The Executive may terminate employment hereunder at any time for any reason, including but not limited to, Good Reason. For purposes of this Agreement, “Good Reason” shall mean that the Executive has completed
all steps of the Good Reason Process (hereinafter defined) following the occurrence of any of the following events without the Executive’s consent (each, a “Good Reason Condition”): 

(i)    a material diminution in the Executive’s Base Salary; 

(ii)    a material diminution in the Executive’s authority, duties or responsibilities, other than as
a result of a Change of Control immediately after which the 

  
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Executive holds a position with the Company or its successor (or any other entity that owns substantially all of the Company’s business after such sale) that is substantially equivalent with
respect to the Company’s business as the Executive held immediately prior to such Change of Control; 

(iii)    a change in the geographic location of the Executive’s principal place of employment to any
location that is more than seventy-five (75) miles from the location immediately prior to such change; 

(iv)    a material breach of this Agreement by the Company; or 

(v)    the failure of the Company to obtain an agreement from any successor to all or substantially all of
the business or assets of the Company to assume this Agreement as contemplated in Section 13 of this Agreement. 
 The “Good Reason
Process” consists of the following steps: 
 (i)    the Executive reasonably determines in good
faith that a Good Reason Condition has occurred; 
 (ii)    the Executive notifies the Company in writing
of the first occurrence of the Good Reason Condition within sixty (60) days of the first occurrence of such condition; 

(iii)    the Executive cooperates in good faith with the Company’s efforts, for a period of not less
than thirty (30) days following such notice (the “Cure Period”), to remedy the Good Reason Condition; 

(iv)    notwithstanding such efforts, the Good Reason Condition continues to exist; and 

(v)    the Executive tenders his resignation within thirty (30) days after the end of the Cure Period.

 If the Company cures the Good Reason Condition during the Cure Period, Good Reason shall be deemed not to have occurred. 

4.    Matters Related to Termination. 

(a)    Notice of Termination. Except for termination as specified in Section 3(a), any termination of the
Executive’s employment by the Company or any such termination by the Executive shall be communicated by written Notice of Termination to the other party hereto. For purposes of this Agreement, a “Notice of Termination” shall
mean a notice which shall indicate the specific termination provision in this Agreement relied upon. 
 (b)    Date
of Termination. “Date of Termination” shall mean: (i) if the Executive’s employment is terminated by death, the date of death; (ii) if the Executive’s employment is terminated on account of disability under
Section 3(b) or by the Company for 

  
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Cause under Section 3(c), the date on which Notice of Termination is given; (iii) if the Executive’s employment is terminated by the Company without Cause under Section 3(d),
the date on which a Notice of Termination is given or the date otherwise specified by the Company in the Notice of Termination; (iv) if the Executive’s employment is terminated by the Executive under Section 3(e) other than for Good
Reason, thirty (30) days after the date on which a Notice of Termination is given or such other date as is mutually agreed by the parties, and (v) if the Executive’s employment is terminated by the Executive under Section 3(e)
for Good Reason, the date on which a Notice of Termination is given after the end of the Cure Period. Notwithstanding the foregoing, in the event that the Executive gives a Notice of Termination to the Company, the Company may unilaterally
accelerate the Date of Termination and such acceleration shall not result in a termination by the Company for purposes of this Agreement. 

(c)    Accrued Obligations. If the Executive’s employment with the Company is terminated for any reason, the
Company shall pay or provide to the Executive (or to the Executive’s authorized representative or estate) (i) any Base Salary earned through the Date of Termination; (ii) any accrued but unpaid vacation (to the extent
applicable), (iii) any unpaid expense reimbursements (subject to, and in accordance with, Section 2(b) of this Agreement); and (iv) any other amounts or benefits, if any, under the Company’s employee benefit plans, programs or
arrangements to which the Executive may be entitled pursuant to the terms of such plans, programs or arrangements or applicable law, payable in accordance with the terms of such plans, programs through the Date of Termination, which vested benefits
shall be paid and/or provided in accordance with the terms of such employee benefit plans (collectively, the “Accrued Obligations”). 

(d)    Resignation of All Other Positions. Upon termination of the Executive’s employment for any reason, the
Executive shall be deemed to have resigned from all positions that he holds as an officer or member of the Board (or committee thereof) of the Company or any of its affiliates. 

5.    Severance Pay and Benefits Upon Termination by the Company without Cause or by the Executive for Good Reason
Outside the Change of Control Period. If the Executive’s employment is terminated by the Company without Cause as provided in Section 3(d), or the Executive terminates employment for Good Reason as provided in Section 3(e), each
outside of the Change of Control Period (as defined below), then, in addition to the Accrued Obligations, and subject to (i) the Executive signing a separation agreement and release in a form and manner reasonably satisfactory to the
Company, which shall include, without limitation, a general release of claims against the Company and all related persons and entities (other than claims for indemnification that survive the Executive’s termination of employment), a
reaffirmation of all of the Executive’s Continuing Obligations (as defined below) and a six (6) month post-employment noncompetition agreement that shall have the same scope of proscribed activities as is described in Section 10(a) of
the Restrictive Covenants Agreement, and shall provide that if the Executive breaches the noncompetition agreement or any of the Continuing Obligations, all payments of the Severance Amount shall immediately cease (the “Separation Agreement
and Release”), and (ii) the Separation Agreement and Release becoming irrevocable, all within sixty (60) days after the Date of Termination (or such shorter period as set forth in the Separation Agreement and Release), which shall
include a seven (7) business day revocation period: 

  
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 (a)    the Company shall pay the Executive an amount equal to
twelve (12) months of the Executive’s Base Salary (the “Severance Amount”); and 

(b)    notwithstanding anything to the contrary in the applicable option agreement, (i) the Performance-Based Options
that would have vested in the twelve (12)-month period following the Date of Termination shall vest subject to the Company’s achievement of the applicable terms set forth in Section 2(e) of this Agreement during the twelve (12)-month
period following the Date of Termination, (ii) if the Date of Termination is within twenty-four (24)-month period following the Effective Date, the Time-Based Options that would have vested in the twelve (12)-month period following the Date of
Termination had the Executive remained employed for such period shall immediately accelerate and become fully exercisable as of the later of (A) the Date of Termination or (B) the effective date of the Separation Agreement and Release (the
“Accelerated Vesting Date”), and (iii) if the Date of Termination is after the twenty-four (24)-month period following the Effective Date, any unvested portion of the Time-Based Options as of the Date of Termination shall
immediately accelerate and become fully exercisable as of the Accelerated Vesting Date; provided that any termination of the unvested portion of the Performance-Based Options or the Time-Based Options to be accelerated pursuant to this
subsection that would otherwise occur on the Date of Termination in the absence of this Agreement will be delayed to effect the terms of this subsection and such termination will subsequently occur if the vesting pursuant to this subsection does not
occur due to the absence of the Separation Agreement and Release becoming fully effective within the time period set forth therein and, in the case of the Performance-Based Options, the failure of the Company to achieve the applicable performance
objectives during the twelve (12)-month period following the Date of Termination. Notwithstanding the foregoing, no additional vesting of the Time-Based Options shall occur during the period between the Executive’s Date of Termination and the
Accelerated Vesting Date; and 
 (c)    if the Executive timely elects continued coverage under COBRA for the Executive
and his covered dependents under the Company’s group health plans following the Date of Termination, then the Company shall pay the COBRA premiums necessary to continue the Executive’s and his covered dependents’ health insurance
coverage in effect on the Date of Termination until the earliest of (x) twelve (12) months following the Date of Termination, (y) the date when the Executive becomes eligible for substantially equivalent health insurance coverage in
connection with new employment or self-employment (and the Executive agrees to promptly notify the Company of such eligibility) and (z) the date the Executive ceases to be eligible for COBRA continuation coverage for any reason, including plan
termination (such period from the Date of Termination through the earlier of (x)-(z), the “COBRA Payment Period”). Notwithstanding the foregoing, if at any time the Company determines that its payment of COBRA premiums on the
Executive’s behalf would result in a violation of applicable law (including but not limited to the 2010 Patient Protection and Affordable Care Act, as amended by the 2010 Health Care and Education Reconciliation Act), then in lieu of paying
COBRA premiums pursuant to this Section 5(c), the Company shall pay the Executive on the last day of each remaining month of the COBRA Payment Period, a fully taxable cash payment equal to the COBRA premium for such month, subject to applicable
tax withholding (such amount, the “Special Severance Payment”), such Special Severance Payment to be made without regard to the Executive’s payment of COBRA premiums. 

  
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 The amounts payable under Section 5, to the extent taxable, shall be paid out in substantially equal
installments in accordance with the Company’s payroll practice over twelve (12) months commencing within sixty (60) days after the Date of Termination; provided, however, that if the sixty
(60)-day period begins in one calendar year and ends in a second calendar year, the Severance Amount, to the extent it qualifies as “non-qualified deferred
compensation” within the meaning of Section 409A of the Internal Revenue Code of 1986, as amended (the “Code”), shall begin to be paid in the second calendar year by the last day of such
60-day period; provided, further, that the initial payment shall include a catch-up payment to cover amounts retroactive to the day immediately following the Date
of Termination. Each payment pursuant to this Agreement is intended to constitute a separate payment for purposes of Treasury Regulation Section 1.409A-2(b)(2). 

6.    Severance Pay and Benefits Upon Termination by the Company without Cause or by the Executive for Good Reason
within the Change of Control Period. The provisions of this Section 6 shall apply in lieu of, and expressly supersede, the provisions of Section 5 if (i) the Executive’s employment is terminated either (a) by the Company
without Cause as provided in Section 3(d), or (b) by the Executive for Good Reason as provided in Section 3(e), and (ii) the Date of Termination is within twelve (12) months after the occurrence of the first event
constituting a Change of Control (such period, the “Change of Control Period”). The provisions of this Section 6 shall have no force or effect outside of a Change of Control Period. 

(a)    If the Executive’s employment is terminated by the Company without Cause as provided in Section 3(d) or
the Executive terminates employment for Good Reason as provided in Section 3(e) and in each case the Date of Termination occurs during the Change of Control Period, then, in addition to the Accrued Obligations, and subject to the signing of the
Separation Agreement and Release by the Executive and the Separation Agreement and Release becoming fully effective, all within the time frame set forth in the Separation Agreement and Release but in no event more than sixty (60) days after the
Date of Termination: 
 (i)    the Company shall pay the Executive a lump sum in cash in an amount equal
to three (3) times the Executive’s then current annual Base Salary (or the Executive’s Base Salary in effect immediately prior to the Change of Control, if higher) (the “Change of Control Payment”); and 

(ii)    notwithstanding anything to the contrary in any applicable option agreement or other stock-based
award agreement, all time-based stock options and other stock-based awards subject to time-based vesting held by the Executive, including, without limitation, the Time-Based Options (collectively, the “Time-Based Equity Awards”)
shall immediately accelerate and become fully exercisable or nonforfeitable as of the Accelerated Vesting Date; provided that any termination or forfeiture of the unvested portion of such Time-Based Equity Awards that would otherwise occur on
the Date of Termination in the absence of this Agreement will be delayed until the effective date of the Separation Agreement and Release and will only occur if the vesting pursuant to this subsection does not occur due to the absence of the
Separation Agreement and Release becoming fully effective within the time period set forth therein. Notwithstanding the foregoing, no additional vesting of the Time-Based Equity Awards shall occur during the period between the Executive’s Date
of Termination and the Accelerated Vesting Date; and 

  
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 (iii)    notwithstanding anything to the contrary in the
option agreement for the Performance-Based Options, if the Company or the successor to or acquiror of the Company’s business (whether by sale of outstanding stock, merger, sale of substantially all the assets or otherwise) elects to assume any
unvested outstanding Performance-Based Options or the common stock of the Company otherwise remains outstanding following the consummation of the Change in Control, the Performance-Based Options that would have vested in the twelve (12)-month period
following the Date of Termination after such Change of Control shall vest subject to the Company’s achievement of the applicable terms set forth in Section 2(e) of this Agreement during such twelve (12)-month period following such Date of
Termination and any termination of the unvested portion of the Performance-Based Options that would otherwise occur on the Date of Termination in the absence of this Agreement will be delayed to effect the terms of this subsection and such
termination will subsequently occur upon the absence of the Separation Agreement and Release becoming fully effective within the time period set forth therein and the failure of the Company to achieve the applicable performance objectives during the
twelve (12)-month period following the Date of Termination. 
 (iv)    if the Executive timely elects
continued coverage under COBRA for the Executive and his covered dependents under the Company’s group health plans following the Date of Termination, then the Company shall pay the COBRA premiums necessary to continue the Executive’s and
his covered dependents’ health insurance coverage in effect on the Date of Termination until the earliest of (x) twelve (12) months following the Date of Termination, (y) the date when the Executive becomes eligible for substantially
equivalent health insurance coverage in connection with new employment or self-employment (and the Executive agrees to promptly notify the Company of such eligibility) and (z) the date the Executive ceases to be eligible for COBRA continuation
coverage for any reason, including plan termination (such period from the Date of Termination through the earlier of (x)-(z), the “COBRA Change of Control Payment Period”). Notwithstanding the foregoing, if at any time the Company
determines that its payment of COBRA premiums on the Executive’s behalf would result in a violation of applicable law (including but not limited to the 2010 Patient Protection and Affordable Care Act, as amended by the 2010 Health Care and
Education Reconciliation Act), then in lieu of paying COBRA premiums pursuant to this Section 6(a)(iv), the Company shall pay the Executive on the last day of each remaining month of the COBRA Change of Control Payment Period, a fully taxable
cash payment equal to the COBRA premium for such month, subject to applicable tax withholding (such amount, the “Special Change of Control Severance Payment”), such Special Change of Control Severance Payment to be made without
regard to the Executive’s payment of COBRA premiums. 
 The amounts payable under this Section 6(a), to the extent taxable, shall be paid or
commence to be paid within sixty (60) days after the Date of Termination; provided, however, that if the 60-day period begins in one calendar year and ends in a second calendar year, such payments to the
extent they qualify as “non-qualified deferred compensation” within the meaning of Section 409A of the Code, shall be paid or commence to be paid in the second calendar year by the last day of such 60-day period. 

  
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 (b)    Additional Limitation. 

(i)    Anything in this Agreement to the contrary notwithstanding, in the event that the amount of any
compensation, payment or distribution by the Company to or for the benefit of the Executive, whether paid or payable or distributed or distributable pursuant to the terms of this Agreement or otherwise, calculated in a manner consistent with
Section 280G of the Code, and the applicable regulations thereunder (the “Aggregate Payments”), would be subject to the excise tax imposed by Section 4999 of the Code, then the Aggregate Payments shall be reduced (but not
below zero) so that the sum of all of the Aggregate Payments shall be $1.00 less than the amount at which the Executive becomes subject to the excise tax imposed by Section 4999 of the Code; provided that such reduction shall only occur if it
would result in the Executive receiving a higher After Tax Amount (as defined below) than the Executive would receive if the Aggregate Payments were not subject to such reduction. In such event, the Aggregate Payments shall be reduced in the
following order, in each case, in reverse chronological order beginning with the Aggregate Payments that are to be paid the furthest in time from consummation of the transaction that is subject to Section 280G of the Code: (1) cash
payments not subject to Section 409A of the Code; (2) cash payments subject to Section 409A of the Code; (3) equity-based payments and acceleration; and (4) non-cash forms of benefits;
provided that in the case of all the foregoing Aggregate Payments all amounts or payments that are not subject to calculation under Treas. Reg. §1.280G-1,
Q&A-24(b) or (c) shall be reduced before any amounts that are subject to calculation under Treas. Reg. §1.280G-1,
Q&A-24(b) or (c). 
 (ii)    For purposes of this
Section 6(b), the “After Tax Amount” means the amount of the Aggregate Payments less all federal, state, and local income, excise and employment taxes imposed on the Executive as a result of the Executive’s receipt of the
Aggregate Payments. For purposes of determining the After Tax Amount, the Executive shall be deemed to pay federal income taxes at the highest marginal rate of federal income taxation applicable to individuals for the calendar year in which the
determination is to be made, and state and local income taxes at the highest marginal rates of individual taxation in each applicable state and locality, net of the maximum reduction in federal income taxes which could be obtained from deduction of
such state and local taxes. 
 (iii)    The determination as to whether a reduction in the Aggregate
Payments shall be made pursuant to Section 6(b)(i) shall be made by a nationally recognized accounting firm selected by the Company (the “Accounting Firm”), which shall provide detailed supporting calculations both to the
Company and the Executive within fifteen (15) business days of the Date of Termination, if applicable, or at such earlier time as is reasonably requested by the Company or the Executive. Any determination by the Accounting Firm shall be binding
upon the Company and the Executive. 

  
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 (c)    Definitions. For purposes of this Section 6,
“Change of Control” shall mean a “Change of Control” as defined in the Company’s 2018 Stock Option and Incentive Plan, except that clause (d) of such definition shall not constitute a Change of Control under this
Agreement. 
 7.    Section 409A. 

(a)    Anything in this Agreement to the contrary notwithstanding, if at the time of the Executive’s separation from
service within the meaning of Section 409A of the Code, the Company determines that the Executive is a “specified employee” within the meaning of Section 409A(a)(2)(B)(i) of the Code, then to the extent any payment or benefit
that the Executive becomes entitled to under this Agreement or otherwise on account of the Executive’s separation from service would be considered deferred compensation otherwise subject to the 20 percent additional tax imposed pursuant to
Section 409A(a) of the Code as a result of the application of Section 409A(a)(2)(B)(i) of the Code, such payment shall not be payable and such benefit shall not be provided until the date that is the earlier of (A) six (6) months and
one day after the Executive’s separation from service, or (B) the Executive’s death. If any such delayed cash payment is otherwise payable on an installment basis, the first payment shall include a
catch-up payment covering amounts that would otherwise have been paid during the six (6)-month period but for the application of this provision, and the balance of the installments shall be payable in
accordance with their original schedule. 
 (b)    All in-kind benefits provided
and expenses eligible for reimbursement under this Agreement shall be provided by the Company or incurred by the Executive during the time periods set forth in this Agreement. All reimbursements shall be paid as soon as administratively practicable,
but in no event shall any reimbursement be paid after the last day of the taxable year following the taxable year in which the expense was incurred. The amount of in-kind benefits provided or reimbursable
expenses incurred in one taxable year shall not affect the in-kind benefits to be provided or the expenses eligible for reimbursement in any other taxable year (except for any lifetime or other aggregate
limitation applicable to medical expenses). Such right to reimbursement or in-kind benefits is not subject to liquidation or exchange for another benefit. 

(c)    To the extent that any payment or benefit described in this Agreement constitutes
“non-qualified deferred compensation” under Section 409A of the Code, and to the extent that such payment or benefit is payable upon the Executive’s termination of employment, then such
payments or benefits shall be payable only upon the Executive’s “separation from service.” The determination of whether and when a separation from service has occurred shall be made in accordance with the presumptions set forth in
Treasury Regulation Section 1.409A-1(h). 
 (d)    The parties intend that
this Agreement will be administered in accordance with Section 409A of the Code. To the extent that any provision of this Agreement is ambiguous as to its compliance with Section 409A of the Code, the provision shall be read in such a
manner so that all payments hereunder comply with Section 409A of the Code. Each payment pursuant to this Agreement or the Restrictive Covenants Agreement is intended to constitute a separate payment for purposes of Treasury Regulation Section 1.409A-2(b)(2). The parties agree that this 

  
 12 

 
Agreement may be amended, as reasonably requested by either party, and as may be necessary to fully comply with Section 409A of the Code and all related rules and regulations in order to
preserve the payments and benefits provided hereunder without additional cost to either party. 
 (e)    The Company
makes no representation or warranty and shall have no liability to the Executive or any other person if any provisions of this Agreement are determined to constitute deferred compensation subject to Section 409A of the Code but do not satisfy
an exemption from, or the conditions of, such Section. 
 8.    Continuing Obligations. 

(a)    Restrictive Covenants Agreement. As a condition of employment, the Executive is required to enter into the
Confidentiality and Noncompetition Agreement attached hereto as Exhibit B (the “Restrictive Covenants Agreement”). For purposes of this Agreement, the obligations in this Section 8 and those that arise in the Restrictive
Covenants Agreement and any other agreement relating to confidentiality, assignment of inventions, or other restrictive covenants shall collectively be referred to as the “Continuing Obligations.” 

(b)    Third-Party Agreements and Rights. The Executive hereby confirms that the Executive is not bound by the
terms of any agreement with any previous employer or other party which restricts in any way the Executive’s use or disclosure of information, other than confidentiality restrictions (if any), or the Executive’s engagement in any business.
The Executive represents to the Company that the Executive’s execution of this Agreement, the Executive’s employment with the Company and the performance of the Executive’s proposed duties for the Company will not violate any
obligations the Executive may have to any such previous employer or other party. In the Executive’s work for the Company, the Executive will not disclose or make use of any information in violation of any agreements with or rights of any such
previous employer or other party, and the Executive will not share with the Company any copies or other tangible embodiments of non-public information belonging to or obtained from any such previous employment
or other party. 
 (c)    Litigation and Regulatory Cooperation. During and after the Executive’s
employment, the Executive shall cooperate fully with the Company in (i) the defense or prosecution of any claims or actions now in existence or which may be brought in the future against or on behalf of the Company which relate to events or
occurrences that transpired while the Executive was employed by the Company, and (ii) the investigation, whether internal or external, of any matters about which the Company believes the Executive may have knowledge or information. The
Executive’s full cooperation in connection with such claims, actions or investigations shall include, but not be limited to, being available to meet with counsel to answer questions or to prepare for discovery or trial and to act as a witness
on behalf of the Company at mutually convenient times. During and after the Executive’s employment, the Executive also shall cooperate fully with the Company in connection with any investigation or review of any federal, state or local
regulatory authority as any such investigation or review relates to events or occurrences that transpired while the Executive was employed by the Company. The Company shall reimburse the Executive for any reasonable out-of-pocket expenses, including, without limitation and unless the Company reasonably determines that it is in the best interest of the Company and the Executive for the Executive not to be represented by
counsel in connection with such cooperation services, reasonable attorney fees, incurred in connection with the Executive’s performance of obligations pursuant to this Section 8(c). 

  
 13 

 (d)    Relief. The Executive agrees that it would be difficult to
measure any damages caused to the Company which might result from any breach by the Executive of the Continuing Obligations, and that in any event money damages would be an inadequate remedy for any such breach. Accordingly, the Executive
agrees that if the Executive breaches, or proposes to breach, any portion of the Continuing Obligations, the Company shall be entitled, in addition to all other remedies that it may have, to an injunction or other appropriate equitable relief to
restrain any such breach without showing or proving any actual damage to the Company. 
 9.    Indemnification.
In the event that the Executive is made a party or threatened to be made a party to any action, suit, or proceeding, whether civil, criminal, administrative or investigative (a “Proceeding”), other than any Proceeding initiated by
the Executive or the Company related to any contest or dispute between the Executive and the Company or any of its affiliates with respect to this Agreement or the Executive’s employment hereunder, by reason of the fact that the Executive is or
was a director or officer of the Company, or any affiliate of the Company, or is or was serving at the request of the Company as a director, officer, member, employee or agent of another corporation or a partnership, joint venture, trust or other
enterprise, the Executive shall be indemnified and held harmless by the Company to the fullest extent applicable to any other officer or director of the Company and/or to the maximum extent permitted under applicable law from and against any
liabilities, costs, claims and expenses, including all costs and expenses incurred in defense of any Proceeding (including attorneys’ fees). This obligation shall survive the termination of this Agreement. 

10.    Consent to Jurisdiction. The parties hereby consent to the jurisdiction of the state and federal courts of
the Commonwealth of Massachusetts. Accordingly, with respect to any such court action, the Executive (a) submits to the exclusive personal jurisdiction of such courts; (b) consents to service of process; and (c) waives
any other requirement (whether imposed by statute, rule of court, or otherwise) with respect to personal jurisdiction or service of process. 

11.    Integration. This Agreement, including Exhibits A and B, constitutes the entire agreement between the
parties with respect to the subject matter hereof and supersedes all prior agreements between the parties concerning such subject matter. 

12.    Withholding; Tax Effect. All payments made by the Company to the Executive under this Agreement shall be net
of any tax or other amounts required to be withheld by the Company under applicable law. Nothing in this Agreement shall be construed to require the Company to make any payments to compensate the Executive for any adverse tax effect associated with
any payments or benefits or for any deduction or withholding from any payment or benefit. 
 13.    Assignment.
Neither the Executive nor the Company may make any assignment of this Agreement or any interest in it, by operation of law or otherwise, without the prior written consent of the other; provided, however, that the Company may assign its rights
and obligations under this Agreement (including the Restrictive Covenants Agreement) without the Executive’s 

  
 14 

 
consent to any affiliate or to any person or entity with whom the Company shall hereafter effect a reorganization, consolidate with, or merge into or to whom it transfers all or substantially all
of its properties or assets; provided further, that the Company will require any successor (whether direct or indirect, by purchase, merger or otherwise) to all or substantially all of the business or assets of the Company to assume this
Agreement. Notwithstanding the foregoing, if the Executive remains employed or becomes employed by the Company, the purchaser or any of their affiliates in connection with any such transaction, then the Executive shall not be entitled to any
payments, benefits or vesting pursuant to Section 5 or pursuant to Section 6 of this Agreement solely as a result of such transaction. This Agreement shall inure to the benefit of and be binding upon the Executive and the Company, and each
of the Executive’s and the Company’s respective successors, executors, administrators, heirs and permitted assigns. 

14.    Enforceability. If any portion or provision of this Agreement (including, without limitation, any portion or
provision of any section of this Agreement) shall to any extent be declared illegal or unenforceable by a court of competent jurisdiction such provision will be deemed to be restated to reflect as nearly as possible the parties’ original
intentions in accordance with applicable law, and the remainder of the Agreement will remain in full force and effect. 

15.    Survival. The provisions of this Agreement shall survive the termination of this Agreement and/or the
termination of the Executive’s employment to the extent necessary to effectuate the terms contained herein. 

16.    Waiver. No waiver of any provision hereof shall be effective unless made in writing and signed by the
waiving party. The failure of any party to require the performance of any term or obligation of this Agreement, or the waiver by any party of any breach of this Agreement, shall not prevent any subsequent enforcement of such term or obligation or be
deemed a waiver of any subsequent breach. 
 17.    Notices. Any notices, requests, demands and other
communications provided for by this Agreement shall be sufficient if in writing and delivered in person or sent by a nationally recognized overnight courier service or by registered or certified mail, postage prepaid, return receipt requested, to
the Executive at the last address the Executive has filed in writing with the Company or, in the case of the Company, at its main offices, attention of the Board. Notices may also be sent by email to the last email address of the Executive or the
Chairperson of the Board (the “Chairperson”), as the case may be; provided that such email notice is promptly thereafter confirmed by one of the foregoing methods. For purposes of email notice, the applicable email address of
the Executive shall be the most recent email address that the Executive has provided to the Company, whereas the Chairperson’s email address shall be the Chairperson’s regular business email address as of the date of notice. 

18.    Amendment. This Agreement may be amended or modified only by a written instrument signed by the Executive
and by a duly authorized representative of the Company. 
 19.    Effect on Other Plans and Agreements. An
election by the Executive to resign for Good Reason under the provisions of this Agreement shall not be deemed a voluntary termination of employment by the Executive for the purpose of interpreting the provisions of any

  
 15 

 
of the Company’s benefit plans, programs or policies. Nothing in this Agreement shall be construed to limit the rights of the Executive under the Company’s benefit plans, programs or
policies except as otherwise provided in Section 8 hereof, and except that the Executive shall have no rights to any severance benefits under any Company severance pay plan, offer letter or otherwise. Except for the Restrictive Covenants
Agreement, in the event that the Executive is party to an agreement with the Company providing for payments or benefits under such plan or agreement and under this Agreement, the terms of this Agreement shall govern and the Executive may receive
payment under this Agreement only and not both. Further, Section 5 and Section 6 of this Agreement are mutually exclusive and in no event shall the Executive be entitled to payments or benefits pursuant to both Section 5 and
Section 6 of this Agreement. 
 20. Governing Law. This is a Massachusetts contract and shall be construed under and be governed
in all respects by the laws of the Commonwealth of Massachusetts without giving effect to the conflict of laws principles thereof. With respect to any disputes concerning federal law, such disputes shall be determined in accordance with the law as
it would be interpreted and applied by the United States Court of Appeals for the First Circuit. 
 21. Conditions. Notwithstanding
anything to the contrary herein, the effectiveness of this Agreement shall be conditioned on (i) the Executive’s satisfactory completion of reference and background checks, if so requested by the Company, and (ii) the Executive’s
submission of satisfactory proof of the Executive’s legal authorization to work in the United States. 
 22. Counterparts. This
Agreement may be executed in any number of counterparts, each of which when so executed and delivered shall be taken to be an original; but such counterparts shall together constitute one and the same document. 

IN WITNESS WHEREOF, the parties have executed this Agreement effective on the Effective Date. 

 

	
	RADIUS HEALTH, INC.
	
	/s/ Owen Hughes
	By: Owen Hughes
	Its: Chairman of the Board of Directors
	
	Date: April 24, 2020
	
	EXECUTIVE
	
	/s/ G. Kelly Martin
	G. Kelly Martin
	
	Date: April 24, 2020 

  
 16 

 Exhibit A 

Outside Activities 
  

	•	 	 Transition Bio (non-employee
co-founder and director) 

  

	•	 	 Wren Therapeutics (Executive Chairman) 

 

	•	 	 Novan – Affiliate until May 3, 2020 

 

	•	 	 Cycle Pharma (passive investor) 

 

	•	 	 Malin Corp (passive investor) 

 Exhibit B 

Restrictive Covenants Agreement 

Confidentiality and Non-Competition Agreement 

In consideration for and as a condition of the commencement of my employment by Radius Health, Inc., (together with its
subsidiaries, affiliates, successors or assigns, the “Company”) and in exchange for, among other things, the opportunity to receive the inducement grants specified in Section 2(e) of the Employment Agreement between me and the Company to
which this Confidentiality and Non-Competition Agreement (this “Agreement”) is attached and the potential accelerated vesting of such inducement grants, as described in the Employment Agreement, and
the receipt of the compensation now and hereafter paid to me by the Company, which I acknowledge and agree is fair and reasonable consideration, I agree as follows: 

1. Definition of Confidential Information. I acknowledge that I may be furnished or have access to confidential, proprietary or trade
secret information relating to the Company’s past, present or future (a) products, processes, formulas, patterns, compositions, compounds, projects, specifications, know how, research data, clinical data, personnel data, compilations,
programs, devices, methods, techniques, inventions, software code, developments, documentation, original works of authorship, designs and technical data, and improvements thereto (collectively, “Technology”); (b) research and development
activities, (c) marketing, business or business development activities, including without limitation prospective or actual bids or proposals, pricing information and financial information; (d) customers or suppliers; or (e) other
administrative, management, planning, financial, marketing, purchasing or manufacturing activities. All of this type of information, whether it belongs to the Company or was provided to the Company by a third party with the understanding that it be
kept confidential, and any documents, diskettes or other storage media, or other materials or items containing this type of information, are proprietary and confidential to the Company (“Confidential Information”). 

2. Obligations. I agree to preserve and protect the confidentiality of Confidential Information both during and after my employment
with the Company. In addition, I agree not to, at any time during the term of this Agreement or thereafter, (a) disclose or disseminate Confidential Information to any third party, including without limitation, employees or consultants of the
Company without a legitimate business need to know; (b) remove Confidential Information from the Company’s premises or make copies of Confidential Information, except as required to perform my job; or (c) use Confidential Information
for my own benefit or for the benefit of any third party. I also agree to take all actions necessary to avoid unauthorized disclosure and otherwise to maintain the confidential or proprietary nature of such Confidential Information. If I am not
certain whether or not information is confidential, I will treat that information as Confidential Information until I have verification from the Company’s Personnel Officer that the information is not Confidential Information. 

3. Exceptions. The Company agrees that the obligations in Section 2 do not apply to any information that I can establish
(a) has become publicly known without a breach of this Agreement by me or a third party’s breach of an agreement to maintain the confidentiality of the 

 
information; or (b) was developed by me outside of the scope of my employment by the Company. For the purposes of clause (a) of the preceding sentence, Confidential Information will be
deemed to have become publicly known only if I can establish that all material features comprising such information have become publicly known. 

4. Former Employer Information. I agree that I will not, during my employment with the Company, improperly use or disclose any
proprietary information or trade secrets of any former or current employer or any other person or entity and that I will not share with the Company any unpublished document or proprietary information belonging to any such employer, person or entity
unless consented to in writing by such employer, person or entity. 
 5. Inventions and Works Retained and Licensed. I have attached
hereto, as Exhibit A, a list describing all Technology which was created, made, conceived, developed or reduced to practice (collectively, “Developed”) by me, solely or jointly, prior to my employment with the Company (collectively
referred to as “Prior Works or Inventions”), which belong to me, which relate to the Company’s business, products, or research and development, and which are not assigned to the Company hereunder, or, if no such list is attached, I
represent that there are no such Prior Works or Inventions. If, in the course of my employment with the Company, I incorporate into a Company product, process or machine, or otherwise use for the benefit of the Company, a Prior Work or Invention,
whether or not listed, owned by me or in which I have an interest, the Company is hereby granted and shall have a nonexclusive, royalty-free, assignable, irrevocable, perpetual, worldwide license to make, have made, modify, reproduce, distribute,
prepare derivative works of, use, import, offer to sell, sell and otherwise exploit such Prior Work or Invention, including without limitation as part of or in connection with such product, process or machine or other use of the same. 

6. Ownership of Work Product. 

(a)    I agree that the Company owns all right, title and interest in, including without limitation all trade secrets,
patent rights, copyrights, trademarks, and other intellectual property rights (collectively, “Intellectual Property Rights”) in the following works that I Develop, solely or jointly, during and for one (1) year after termination of my
employment with the Company: (i) Technology that is created using the Company’s facilities, supplies, information, trade secrets or time, (ii) Technology that relates directly or indirectly to or arises out of the actual or proposed
business of the Company, including, without limitation the research and development activities of the Company, (iii) Technology that relates directly or indirectly to or arises out of any task assigned to me or work I perform for the Company or
(iv) Technology that is based on the Company’s Confidential Information (collectively “Work Product”). I will promptly provide full written disclosure to an officer of the Company of any Work Product I Develop, solely or jointly,
during the term and for a period of one (1) year thereafter. I hereby irrevocably assign and agree to assign to the Company the ownership of, and all Intellectual Property Rights in, the Work Product. The Company will have the right to hold in
its own all rights in the Work Product, including without limitation all Intellectual Property Rights therein. I also waive all claims to moral rights in any Work Product. 

 (b)    I agree to cooperate fully with the Company, both during and
after my employment with the Company, with respect to the procurement, maintenance and enforcement of copyrights, patents and other Intellectual Property Rights (both in the United States and foreign countries) relating to Work Product, and the
Company shall reimburse me for my reasonable costs incurred in connection with such cooperation. I agree to execute and deliver all papers, including, without limitation, copyright applications, patent applications, declarations, oaths, formal
assignments, assignments of priority rights, and powers of attorney, which the Company may deem necessary or desirable to protect its rights and interests in any Work Product. I further agree that if the Company is unable, after reasonable effort,
to secure my signature on any such papers, any executive officer of the Company shall be entitled to execute any such papers as my agent and attorney-in-fact, and I
hereby irrevocably designate and appoint each executive officer of the Company as my agent and attorney-in-fact to execute any such papers on my behalf, and to take any
and all actions as the Company may deem necessary or desirable to protect its rights and interests in any Work Product, under the conditions described in this sentence. 

7. Maintenance of Records. I agree to keep and maintain adequate and current written records of all Work Product made by me (solely or
jointly with others) during the term of my employment with the Company. The records will be in the form of notes, sketches, drawings, and any other format that may be specified by the Company. The records will be available to and remain the sole
property of the Company at all times. 
 8. Return of Confidential Information. I agree to return to the Company all Confidential
Information in my possession, custody or control immediately upon my termination, or earlier, from the Company for any reason, if the Company requests. 

9. Notification of New Employer. In the event I leave the employ of the Company for any reason, I hereby grant consent to notification
by the Company to my new employer about my rights and obligations under this Agreement. 
 10. Noncompetition; Nonsolicitation of
Employees. In order to protect the value of any Confidential Information and the Company’s goodwill, I agree to the following provisions against unfair competition, which I acknowledge represent a fair balance of the Company’s rights
to protect its business and my right to pursue employment: 
 (a)    While I am employed (whether as an employee or
consultant) at the Company and for a period (the “Restricted Period”) immediately following termination of such employment (for any reason whatsoever, whether voluntary or involuntarily) of (i) one (1) year or (ii) two (2) years
following the last day of my employment if I breach my fiduciary duty to the Company or if I have unlawfully taken, physically or electronically, property belonging to the Company, I agree that I will not, whether alone or as a partner, officer,
director, consultant, agent, representative, employee or security holder of any company or their commercial enterprise, directly or indirectly engage in, have an equity interest in, interview for a potential employment or consulting relationship
with or manage, provide services to or operate any person, firm, corporation, partnership, association, other entity or business or other activity anywhere in the world that engages in business that is competitive with or renders services to any
firm or 

 
business organization which competes with the business of the Company, which business includes, without limitation, the research, discovery, development and/or commercialization of therapeutics
to treat osteoporosis or related endocrine diseases, or any other therapeutic areas that the Company is actively engaged in at the time of termination of my employment (the “Company’s Business”); provided, that the Company’s
Business shall not include any business that the Company has not taken more than de minimis steps to engage in at the time of the termination of my employment. The foregoing prohibition shall not prevent my employment or engagement after termination
if such employment or engagement, in any capacity, does not involve work or matters related to the Company’s Business, nor shall it prevent me from owning securities of a public company not in excess of five percent (5%) of any class of such
securities and to own stock partnership interests or other securities of any entity not in excess of five percent (5%) of any class of such securities. Notwithstanding the foregoing, I shall not be subject to the restrictions of this
Section 10(a) after my employment with the Company ends (nor entitled to the Noncompetition Consideration set forth below) if the Company terminates my employment without Cause or lays me off, or if I resign my employment for Good Reason. For
purposes of this Agreement, “Cause” and “Good Reason” shall have the meanings ascribed to such terms in the Employment Agreement. For the avoidance of doubt, if I resign my employment other than for Good Reason or if the Company
terminates my employment with Cause, this Section 10(a) shall be in full force and effect unless the Company waives it rights under this Section 10(a) pursuant to Section 13(a) below. For its part, the Company agrees to provide the
Noncompetition Consideration to me in exchange for my post-employment obligations under this Section 10(a); provided that the Company may waive its rights under this Section 10(a) pursuant to Section 13(a) below and in such
event, the Company shall not be obligated to provide the Noncompetition Consideration. The “Noncompetition Consideration” consists of payments to me for the post-employment portion of the Restricted Period (but for not more than twelve
(12) months following the end of my employment) at the rate of 50% of the highest annualized base salary paid to me by the Company within the two-year period preceding the last day of my employment. I
acknowledge that this covenant is necessary because the Company’s legitimate business interests cannot be adequately protected solely by the other covenants in this Agreement. I further acknowledge and agree that any payments I receive pursuant
to this Section 10(a) shall reduce (and shall not be in addition to) any severance or separation pay that I am otherwise entitled to receive from the Company pursuant to an agreement, plan or otherwise. 

(b)    While I am employed (whether as an employee or consultant) at the Company and for the Restricted Period, I agree
that I will not (i) directly or indirectly, solicit, recruit or induce any employee, customer, subscriber, supplier, vendor or business affiliate of the Company to terminate its employment or other arrangement with the Company or otherwise
alter its relationship with the Company or (ii) directly or indirectly, for myself or any other person or entity, solicit or recruit any employee of the Company to work for a third party other than the Company or hire any such employee during
the employee’s employment with the Company and for a period of twelve (12) months following the employee’s employment with the Company or engage in any activity that would cause or encourage any employee to violate any agreement with
the Company. 

 (c)    In the event the terms of this Section 10 shall be
determined by any court of competent jurisdiction to be unenforceable by reason of its extending for too great a period of time or over too great a geographical area or by reason of its being too extensive in any other respect, it will be
interpreted to extend only over the maximum period of time for which it may be enforceable, over the maximum geographical area as to which it may be enforceable, or to the maximum extent in all other respects as to which it may be enforceable, all
as determined by such court in such action. 
 11. Representations and Warranties. I represent and warrant that (a) I am able to
perform the duties of my position and that my ability to work for the Company is not limited or restricted by any agreements or understandings between me and other persons or companies; (b) I will not disclose to the Company, its employees,
consultants, clients, teaming partners or suppliers, or induce any of them to use or disclose, any confidential information or material belonging to others, except with the written permission of the owner of the information or material; and
(c) any information, material or product I create or develop for, or any advice I provide to, the Company, its employees, consultants, clients, teaming partners or suppliers, will not rely or be based on confidential information or trade
secrets I obtained or derived from a source other than the Company. I agree to indemnify and hold the Company harmless from damages, claims, costs and expenses based on or arising from the breach of any agreement or understanding between me and
another person or company or from my use or disclosure of any confidential information or trade secrets I obtained from sources other than the Company. 

12. Damages and Injunctive Relief. I acknowledge and agree that: 

(a)    My obligations under this Agreement have a unique and substantial value to the Company and I remain obligated even
if I voluntarily or involuntarily leave the Company’s employment. I understand that if I violate this Agreement during or after my employment, the Company may be able to recover monetary damages from me and/or the other relief described below.

 (b)    I agree that a violation or even a threatened violation of this Agreement is likely to result in irreparable
harm to the Company and its goodwill, the exact amount of which will be difficult or impossible to ascertain, and monetary damages alone will not completely compensate the Company for the harm. Accordingly, the Company may obtain an injunction
prohibiting me from violating this Agreement, an order requiring me to render specific performance of the Agreement, and/or any other remedy which may be available at law or in equity. 

(c)    If a court determines that I have breached or attempted or threatened to breach this Agreement, I consent to the
granting of an injunction restraining me from further breaches or attempted or threatened breaches of this Agreement, compelling me to comply with this Agreement, and/or prescribing other equitable remedies. 

 13. Miscellaneous Provisions. 

(a)     The Company and I acknowledge and agree that the Company’s election not to provide me with the Noncompetition
Consideration as set forth in Section 10(a) shall be deemed a waiver of my noncompetition obligations under Section 10(a). Otherwise, no failure or delay to act by the Company will waive any right, remedy or power contained in this
Agreement and any waiver by the Company must be in writing and signed by the Chairperson of the Board of Directors of the Company to be effective. 

(b)    The provisions of this Agreement are applicable to Confidential Information and Work Product disclosed, developed
or proprietary before or after I sign this Agreement. 
 (c)    I understand that nothing contained in this Agreement
limits my ability to communicate with any federal, state or local governmental agency or commission. I further understand that pursuant to the federal Defend Trade Secrets Act of 2016, I shall not be held criminally or civilly liable under any
federal or state trade secret law for the disclosure of a trade secret that (a) is made (i) in confidence to a federal, state, or local government official, either directly or indirectly, or to an attorney; and (ii) solely for the
purpose of reporting or investigating a suspected violation of law; or (b) is made in a complaint or other document filed in a lawsuit or other proceeding, if such filing is made under seal. 

(d)    This Agreement is to be construed according to its fair meaning and not strictly for or against either party. 

(e)    This Agreement will be governed by the law of the Commonwealth of Massachusetts without regard to its conflicts of
laws provisions that would result in the application of the laws of any other jurisdiction. Suit to enforce any provision of this Agreement or to obtain any remedy with respect hereto may be brought in a courts of the Commonwealth of Massachusetts
and for this purpose I expressly consent to the jurisdiction of said courts; provided, however, the Company and I agree that all civil actions relating to Section 10(a) of this Agreement shall be brought in the county of Suffolk and that the
superior court or the business litigation session of the superior court shall have exclusive jurisdiction. 
 (f)    If
any provision of this Agreement conflicts with the law of the Commonwealth of Massachusetts or if any provision is held invalid by a court with jurisdiction over the parties to this Agreement, the provision will be deemed to be restated to reflect
as nearly as possible the parties’ original intentions in accordance with applicable law, and the remainder of the Agreement will remain in full force and effect. If it is not possible to restate the provision in a legal and valid manner, then
the provision will be deemed not to be a part of the Agreement and the remaining provisions will remain in full force and effect. 

(g)    This document constitutes the entire agreement between the Company and me concerning the matters addressed in this
Agreement and with respect to all periods after the date hereof it supersedes any prior agreement concerning those matters. This Agreement shall constitute the Confidentiality and Noncompetition Agreement for purposes of the Employment

 
Agreement between me and the Company. This Agreement may not be changed in any respect except by a written agreement signed by both parties. Any subsequent change or changes in my duties, salary
or compensation will not affect the validity or scope of this Agreement. 
 (h)    My obligations under this Agreement
are independent of any obligation, contractual or otherwise, the Company has to me. The Company’s breach of any such obligation shall not be a defense against the enforcement of this Agreement or otherwise limit my obligations under this
Agreement 
 (i)    All remedies provided in this Agreement are cumulative and in addition to all other remedies which
may be available at law or in equity. 
 [Remainder of page intentionally left blank.] 

 I UNDERSTAND THAT THIS AGREEMENT AFFECTS IMPORTANT RIGHTS. BY SIGNING BELOW, I CERTIFY THAT
(I) I WAS PROVIDED WITH THIS AGREEMENT AT LEAST TEN (10) BUSINESS DAYS BEFORE THE EFFECTIVE DATE OF THIS AGREEMENT AND (II) I HAVE BEEN ADVISED BY THE COMPANY THAT I HAVE THE RIGHT TO CONSULT WITH COUNSEL PRIOR TO SIGNING THIS
AGREEMENT.     
 IN WITNESS WHEREOF, the undersigned has executed this agreement as a sealed instrument and it shall
become effective upon the later of the (i) full execution by both parties; or (ii) ten (10) business days after the Company provided me with notice of this Agreement. 

 

					
	Signature:	  	  
	  	
			
	Print Name:	  	  
	  	
			
	Date:	  	  
	  	
			
	THE COMPANY:	  	RADIUS HEALTH, INC.	  	
			
	By:	  	  
	  	
			
	Title:	  	  
	  	

 EXHIBIT A 

 

					
	To:	 	RADIUS HEALTH, INC.	  	
			
	From:	 	  
	  	
			
	Date:	 	  
	  	

 SUBJECT:         Prior Works or
Inventions 
 The following is a complete list of all Technology (as defined in the Confidentiality and Noncompetition Agreement) that has been created,
made, conceived, developed or reduced to practice by me, solely or jointly, prior to my employment with the Company, which belong to me, which relate to the Company’s business, products, or research and development, and which are not assigned
to the Company: 
 ☐      No Prior Works or Inventions 

☐      See below: 
  

                    
                                         
                                         
                                         
                  

                    
                                         
                                         
                                         
                  
  

                    
                                         
                                         
                                         
                  

☐      Additional sheets attached 

The following is a list of all patents and patent applications in which I have been named as an inventor: 

☐      None 

☐      See below:EX-10.2

 Exhibit 10.2 

NON-QUALIFIED STOCK OPTION AGREEMENT 

INDUCEMENT STOCK OPTION GRANT (TIME-BASED) 
  

			
	Name of Optionee:	  	G. Kelly Martin
		
	No. of Option Shares:	  	575,000
		
	Option Exercise Price per Share:	  	$16.46
		
	Grant Date:	  	April 28, 2020
		
	Vesting Commencement Date:	  	April 28, 2020
		
	Expiration Date:	  	April 27, 2030

 Radius Health, Inc. (the “Company”) hereby grants to the Optionee named above an option (the “Stock
Option”) to purchase on or prior to the Expiration Date specified above all or part of the number of shares of Common Stock, par value 0.0001 per share (the “Stock”) of the Company specified above at the Option Exercise Price per
Share specified above subject to the terms and conditions set forth herein. This Stock Option is not issued under the Radius Health, Inc. 2018 Stock Option and Incentive Plan, as amended through the date hereof (the “Plan”) and does not
reduce the share reserve under the Plan. However, for purposes of interpreting the applicable provisions of this Stock Options, the terms and conditions of the Plan (other than those applicable to the share reserve) shall govern and apply to this
Stock Option as if this Stock Option had actually been issued under the Plan. This Stock Option is not intended to be an “incentive stock option” under Section 422 of the Internal Revenue Code of 1986, as amended. 

This Stock Option is intended to constitute an “employment inducement grant” under NASDAQ Listing Rule 5635(c)(4), and consequently is intended to
be exempt from the NASDAQ rules regarding stockholder approval of equity compensation plans. This Agreement and the terms and conditions of this Stock Option shall be interpreted in accordance with and consistent with such exemption. 

1. Exercisability Schedule. No portion of this Stock Option may be exercised until such portion shall have become exercisable. Except as set forth
below, and subject to the discretion of the Administrator (as defined in Section 2 of the Plan) to accelerate the exercisability schedule hereunder, this Stock Option shall vest and become exercisable as to 25% of the number of Option Shares on
the first anniversary of the Vesting Commencement Date and as to 1/48th of the number of Option Shares on the same day of each of the 36 consecutive months thereafter, provided that each Option Share which would be fractionally vested shall be
cumulated and shall vest on the first vesting date upon which the whole Option Share has cumulated, and provided further that the Optionee has a continuing Service Relationship with the Company or a Subsidiary or any successor entity on such dates.

 Once exercisable, this Stock Option shall continue to be exercisable at any time or times prior to the close of business on the Expiration Date, subject
to the provisions hereof and of the Plan. 
 2. Manner of Exercise. 

(a) The Optionee may, from time to time on or prior to the Expiration Date of this Stock Option, exercise this Stock Option only by completing the transaction
through the Company’s administrative agent’s website or by calling its toll free number, specifying the number of Option Shares being purchased as a result of such exercise, together with payment of the full purchase price for the Option
Shares being purchased. The transfer to the Optionee on the records of the Company or of the transfer agent of the Option Shares will be contingent upon (i) the Company’s receipt from the Optionee of the full purchase price for the Option
Shares, as set forth above, (ii) the fulfillment of any other requirements contained herein or in the Plan or in any other agreement or provision of laws, and (iii) the receipt by the Company of any agreement, statement or other evidence
that the Company may require to satisfy itself that the issuance of Stock to be purchased pursuant to the exercise of Stock Options under the Plan and any subsequent resale of the shares of Stock will be in compliance with applicable laws and
regulations. However, during any period that this Stock Option remains outstanding after the Optionee’s Service Relationship with the 

 
Company ends, the Optionee may exercise it only to the extent it was exercisable immediately prior to the end of the Optionee’s Service Relationship. In addition to the procedure for
exercising this Stock Option as described in Section 5 of the Plan, the Optionee may elect, upon prior written notice to the Company, to have any employee withholding tax obligations resulting from the exercise of this Stock Option satisfied by
a reduction in the number of shares of Stock issuable to the Optionee upon exercise. 
 (b) The shares of Stock purchased upon exercise of this Stock Option
shall be transferred to the Optionee on the records of the Company or of the transfer agent upon compliance to the satisfaction of the Administrator with all requirements under applicable laws or regulations in connection with such transfer and with
the requirements hereof and of the Plan. The determination of the Administrator as to such compliance shall be final and binding on the Optionee. The Optionee shall not be deemed to be the holder of, or to have any of the rights of a holder with
respect to, any shares of Stock subject to this Stock Option unless and until this Stock Option shall have been exercised pursuant to the terms hereof, the Company or the transfer agent shall have transferred the shares to the Optionee, and the
Optionee’s name shall have been entered as the stockholder of record on the books of the Company. Thereupon, the Optionee shall have full voting, dividend and other ownership rights with respect to such shares of Stock. 

(c) In no event may a fraction of a share be exercised or acquired. 

(d) Notwithstanding any other provision hereof or of the Plan, no portion of this Stock Option shall be exercisable after the Expiration Date hereof. 

3. Termination of Service Relationship. If the Optionee’s Service Relationship with the Company or a Subsidiary or any successor entity is
terminated, the period within which to exercise the Stock Option may be subject to earlier termination as set forth below. 
 (a) Termination Due to
Death. If the Optionee’s Service Relationship terminates by reason of the Optionee’s death, any portion of this Stock Option outstanding on such date, to the extent exercisable on the date of death, may thereafter be exercised by the
Optionee’s legal representative or legatee for a period of 12 months from the date of death or until the Expiration Date, if earlier. Any portion of this Stock Option that is not exercisable on the date of death shall terminate immediately and
be of no further force or effect. 
 (b) Termination Due to Disability. If the Optionee’s Service Relationship terminates by reason of the
Optionee’s disability (as determined by the Administrator), any portion of this Stock Option outstanding on such date, to the extent exercisable on the date of such termination of the Service Relationship, may thereafter be exercised by the
Optionee for a period of 12 months from the date of disability or until the Expiration Date, if earlier. Any portion of this Stock Option that is not exercisable on the date of disability shall terminate immediately and be of no further force or
effect. 
 (c) Termination for Cause. If the Optionee’s Service Relationship terminates for Cause, any portion of this Stock Option outstanding
on such date shall terminate immediately and be of no further force and effect. For purposes hereof, “Cause” shall have the meaning set forth in the Employment Agreement (as such term is defined below). 

(d) Other Termination. If the Optionee’s Service Relationship terminates for any reason other than the Optionee’s death, the Optionee’s
disability or Cause, and unless otherwise determined by the Administrator, any portion of this Stock Option outstanding on such date may be exercised, to the extent exercisable on the date of termination, for a period of three months from the date
of termination or until the Expiration Date, if earlier. Except as set forth in Section 4 below, any portion of this Stock Option that is not exercisable on the date of termination shall terminate immediately and be of no further force or
effect. 
 The Administrator’s determination of the reason for termination of the Optionee’s Service Relationship shall be conclusive and binding
on the Optionee and his or her representatives or legatees. 

 4. Vesting Upon Certain Qualifying Terminations. Notwithstanding the provisions of Sections 1 or 3
above, this Stock Option shall vest and become exercisable as follows: 
 (a) Termination by the Company without Cause or by the Optionee for Good Reason
Outside the Change of Control Period. If the Optionee’s Service Relationship is terminated by the Company without Cause or by the Optionee for Good Reason (as each term is defined in the Optionee’s employment agreement dated
April 24, 2020 by and between the Optionee and the Company, as the same may be amended from time to time (the “Employment Agreement”)) outside of the 12-month period following the occurrence of
the first event constituting a Change of Control (as defined in the Plan) (the “Change of Control Period”), subject to the Optionee’s execution and non-revocation of a separation agreement and
release in a form and manner reasonably satisfactory to the Company (the “Separation Agreement and Release”): 
 (i) If the date the
Optionee’s Service Relationship is terminated (the “Date of Termination”) is within the twenty-four (24)-month period following the effective date of the Employment Agreement, the portion of this Stock Option that would have vested in
the twelve (12)-month period following the Date of Termination had the Optionee remained a service provider to the Company for such period shall immediately accelerate and become fully exercisable as of the later of (A) the Date of Termination
or (B) the effective date of the Separation Agreement and Release (the “Accelerated Vesting Date”); and 
 (ii) If the Date of Termination is
after the twenty-four (24)-month period following the effective date of the Employment Agreement, any unvested portion of this Stock Option as of the Date of Termination shall immediately accelerate and become fully exercisable as of the Accelerated
Vesting Date. 
 (b) Termination by the Company without Cause or by the Optionee for Good Reason within the Change of Control Period. If the
Optionee’s employment is terminated by the Company without Cause or by the Optionee for Good Reason (as each term is defined in the Employment Agreement) within the Change of Control Period, subject to the Optionee’s execution and non-revocation of a Separation Agreement and Release: 
 (i) Any unvested portion of the Stock Option as of the Date of
Termination shall immediately accelerate and become fully exercisable as of the Accelerated Vesting Date. 
 (c) Tolling of Termination of Stock
Option. Notwithstanding anything to the contrary contained in this Section 4, any termination of the unvested portion of this Stock Option to be accelerated pursuant to this Section 4 that would otherwise occur on the Date of
Termination in the absence of this Agreement will be delayed to effect the terms of this Section 4 and such termination will subsequently occur if the vesting pursuant to this subsection does not occur due to the absence of the Separation
Agreement and Release becoming fully effective within the time period set forth therein. Notwithstanding the foregoing, no additional vesting of this Stock Option shall occur during the period between the Date of Termination and the Accelerated
Vesting Date. 
 5. Incorporation of Plan. As set forth above, this Stock Option is not granted pursuant to the Plan. However, for purposes of
interpreting the provisions of this Stock Option, the terms and conditions of the Plan (other than those applicable to the share reserve, but including the powers of the Administrator set forth in Section 2(b) of the Plan) shall govern and
apply to this Stock Option as if this Stock Option had actually been issued under the Plan. Capitalized terms in this Agreement shall have the meaning specified in the Plan, unless a different meaning is specified herein. 

6. Transferability. This Agreement is personal to the Optionee, is non-assignable and is not transferable in
any manner, by operation of law or otherwise, other than by will or the laws of descent and distribution. This Stock Option is exercisable, during the Optionee’s lifetime, only by the Optionee, and thereafter, only by the Optionee’s legal
representative or legatee. 
 7. Tax Withholding. The Optionee shall, not later than the date as of which the exercise of this Stock Option becomes a
taxable event for Federal income tax purposes, pay to the Company or make arrangements satisfactory to the Administrator for payment of any Federal, state, and local taxes required by law to be withheld on account of such taxable event. The Company
shall have the authority to cause the required tax withholding obligation to be satisfied, in whole or in part, by withholding from shares of Stock to be issued to the Optionee a number of shares of Stock with an aggregate Market Value that would
satisfy the minimum withholding amount due. 

 8. No Obligation to Continue Service Relationship. Neither the Company nor any Subsidiary is
obligated by or as a result of the Plan or this Agreement to continue the Optionee’s Service Relationship with the Company or a Subsidiary or any successor entity, and neither the Plan nor this Agreement shall interfere in any way with the
right of the Company or any Subsidiary to terminate the Optionee’s Service Relationship at any time. 
 9. Integration. This Agreement
constitutes the entire agreement between the parties with respect to this Stock Option and supersedes all prior agreements and discussions between the parties concerning such subject matter. 

10. Data Privacy Consent. In order to administer the Plan and this Agreement and to implement or structure future equity grants, the Company, its
subsidiaries and affiliates and certain agents thereof (together, the “Relevant Companies”) may process any and all personal or professional data, including but not limited to Social Security or other identification number, home address
and telephone number, date of birth and other information that is necessary or desirable for the administration of the Plan and/or this Agreement (the “Relevant Information”). By entering into this Agreement, the Optionee
(i) authorizes the Company to collect, process, register and transfer to the Relevant Companies all Relevant Information; (ii) waives any privacy rights the Optionee may have with respect to the Relevant Information; (iii) authorizes
the Relevant Companies to store and transmit such information in electronic form; and (iv) authorizes the transfer of the Relevant Information to any jurisdiction in which the Relevant Companies consider appropriate. The Optionee shall have
access to, and the right to change, the Relevant Information. Relevant Information will only be used in accordance with applicable law. 
 11.
Notices. Notices hereunder shall be mailed or delivered to the Company at its principal place of business and shall be mailed or delivered to the Optionee at the address on file with the Company or, in either case, at such other address as
one party may subsequently furnish to the other party in writing. 
 12. Acceptance of Option. The Optionee must execute this Agreement by logging on
to the Company’s administrative agent’s website for the Plan. IF THE OPTIONEE DOES NOT ELECTRONICALLY ACCEPT THIS STOCK OPTION THROUGH THE WEBSITE WITHIN THIRTY (30) DAYS FOLLOWING THE GRANT DATE AND THEREBY ACCEPT THE TERMS AND
CONDITIONS OF THIS AGREEMENT AND THE PLAN, THEN THE OPTIONEE WILL BE DEEMED TO HAVE DECLINED THE STOCK OPTION AND THE STOCK OPTION WILL BE NULL AND VOID (AND THE OPTIONEE WILL HAVE NO RIGHTS WITH RESPECT TO THE STOCK OPTION). 

 IN WITNESS WHEREOF, the
parties have executed this Agreement as a sealed instrument as of the date first above written. 
 RADIUS HEALTH, INC. 

 

					
	By: /s/ Owen Hughes	  		  	/s/ G. Kelly Martin
	Name: Owen Hughes 	  		  	Signature of Optionee
	Title: Chairman of the Board of Directors

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