Document:

Amendatory and Supplemental Letter Agreement

 Exhibit 10.117 
  

			
		  	Page 1

 [Argent Development Group, LLC Letterhead] 
 Kenneth R. Greathouse 
 President                        
 October 12, 2006 
 Accentia Biopharmaceuticals, Inc. 
 324 South Hyde Park Avenue, Suite 350 
 Tampa, FL 33606 
  

			
	Attn:	  	Alan Pearce
		  	Chief Financial Officer

 Amendatory and Supplemental Letter Agreement 
 Dear Alan, 
 This Amendatory and Supplement Letter Agreement (this
“Amendatory and Supplemental Letter Agreement”) is with regard to the Letter Agreement dated October 4, 2006, among Ryan Pharmaceuticals, Inc. (“Ryan”) and Argent Development Group, LLC (“Argent”), on the one hand,
and Accentia Biopharmaceuticals, Inc. and TEAMM Pharmaceuticals, Inc. (hereafter collectively “Accentia/TEAMM”), on the other hand (the “Letter Agreement”), which Letter was signed on behalf of all of the parties on
October 5, 2006. 
 For and in consideration of One Hundred Thousand Dollars ($100,00) to be paid by Accentia/TEAMM to Ryan and Argent as set forth in
Section 3 below, and other good and valuable consideration as set forth herein below, the parties do hereby agree as follows: 
  

	 	1.	Capitalized terms used herein that are not otherwise define shall have the meanings given to them in the Letter Agreement or the Distribution Agreements (as amended) as referred to
in the Letter Agreement. 

  

	 	2.	“October 16, 2006” as set forth in Section 2, 3, 4, 5 [two (2) instances] and Section 7 [three (3) instances] of the Letter Agreement are hereby
deleted and replaced in each instance with “October 23, 2006” and the single use of “October 17, 2006” in Section 7 of the Letter Agreement is hereby deleted and replaced with “October 24, 2006”.

  

	 	3.	One Hundred Thousand Dollars ($100,000) is to be paid by Accentia/TEAMM to Ryan and Argent as follows: 

  

	 	(a)	Fifty Thousand Dollars ($50,000) is to be paid by Accentia/TEAMM to Ryan by wire transfer no later than 5:00pm PDT, Friday, October 13, 2006. 

  

	 	(b)	Fifty Thousand Dollars ($50,000) is to be paid by Accentia/TEAMM to Ryan by wire transfer no later than 5:00pm PDT, Friday, October 13, 2006. 

			
	[Argent Development Group, LLC]	  	Page 2

  

	 	(c)	All of the One Hundred Thousand Dollars ($100,000) is to be retained by Ryan and Argent whether or not Accentia/TEAMM obtain the fully paid-up license to the X/300 Products as set
forth in the Letter Agreement. 

  

	 	(d)	If, however, Accentia/TEAMM satisfy in full and on time their obligations as set forth in Sections 2-4 of the Letter Agreement as amended herby (it being acknowledged by Ryan and
Argent that Accentia/TEAMM have already satisfied their obligation as set forth in Section 1 of the Letter Agreement) and thus have obtained the fully paid-up licenses to the X/300 Products as set forth in the Letter Agreement, then Twenty-five
Thousand Dollars ($25,000) of each payment by Accentia/TEAMM pursuant to Sections 3(a) and 3(b) hereof, totaling Fifty Thousand Dollars ($50,000), shall be credited against the amounts to be paid by Accentia/TEAMM under Section 2 of the Letter
Agreement to Ryan and Section 3 of the Letter Agreement to Argent. 

  

	 	4.	If, however, Accentia/TEAMM do not satisfy in full and on time all of their obligations as set forth in Sections 2-4 of the Letter Agreement and thus have not obtained the fully
paid-up license to the X/300 Products set forth in the Letter Agreement, and Ryan and Argent have exercised their rights under Section 7 of the Letter Agreement and, accordingly, have acquired the sole right to find one or more alternative
marketing partners, in place of Accentia/TEAMM, to market the X/300 Products, then as further consideration to Ryan and Argent, Accentia/TEAMM agree to assign, and do hereby assign, to Argent TEAMM’s United States trademark Registration
No. 2943009 (dated April 19, 2005) to XODOL on a fully paid-up, royalty-free basis. In furtherance of this provision, the third sentence of Section 11.3 of the Argent Distribution Agreement reading “Should Argent elect to
continue distribution of any of the Products utilizing the trademark(s) and/or tradename(s) for any of the Products, Argent shall be TEAMM perpetual royalties equal to eight percent (8%) of Net Sales received by Argent for such Products,”
shall be deleted therefrom if and when this Section 4 becomes operative. 

  

	 	5.	Except as set forth herein, the Ryan Distribution Agreement (as amended), the Argent Distribution Agreement (as amended), and the Letter Agreement remain in full force and effect.

  

	 	6.	If by 5:00pm PDT on Friday, October 13, 2006 (a) the payments set forth in Section 3(a) and 3(b) are not received by Ryan and Argent and (b) this Amendatory and
Supplemental Letter Agreement is not fully executed and accepted by Accentia/TEAMM and returned to Ryan and Argent (without any change or modification), this Amendatory and Supplemental Letter Agreement shall be considered rescinded by Ryan and
Argent and Ryan and Argent shall have no future obligation to enter into this (or any other amendatory or supplemental letter agreement or to do so on any terms and conditions as are contained herein. 

  

	 	7.	 This Amendatory and Supplemental Letter Agreement shall be governed by and interpreted, and all rights and obligations of the parties shall be determined, in
accordance with the laws of the State of California, without regard to its conflict of laws rules. All disputes with respect to this Amendatory and Supplemental Letter Agreement, which cannot be resolved by good faith negotiation among the parties,
shall be brought and heard either in the California State Courts located in Santa Clara County or the United States District Court for the Northern District of California located in San Jose, California. The parties to this Amendatory and
Supplemental Letter Agreement each 

			
	[Argent Development Group, LLC]	  	Page 3

  

 
consent to the in personam jurisdiction and venue of such courts. The parties agree that service of process upon them in any such action may be made if
delivered in person, by courier service, by facsimile or by certified mail, postage prepaid, return receipt requested, and shall be deemed effectively given upon confirmed receipt thereof. 
  

	 	8.	This Amendatory and Supplemental Letter Agreement is binding upon the parties hereto and supersedes any previous agreements, commitments, communications, negotiations, offers
(whether oral or in writing), representations, statements, understandings and writings related to the circumstances outlined in this Amendatory and Supplemental Letter Agreement. 

 IN WITNESS WHEREOF, this Amendatory and Supplemental Letter Agreement has been executed and delivered by their duly authorized officers to be effective as of
October 13, 2006. 
  

			
	Ryan Pharmaceuticals, Inc.
		
	By:	 	 /s/ Patricia Ryan

		 	Patricia Ryan
		 	President
		 	Date: October 13, 2006
	
	Argent Development Group, LLC
		
	By:	 	 /s/ Kenneth Greathouse

		 	Kenneth Greathouse
		 	President
		 	Date: October 13, 2006
	
	Accentia Biopharmaceuticals, Inc.
		
	By:	 	 /s/ Alan Pearce

		 	Alan Pearce
		 	Chief Financial Officer
		 	Date: October 13, 2006
	
	TEAMM Pharmaceuticals, Inc.
		
	By:	 	 /s/ Francis E. O’Donnell, Jr.

		 	Francis E. O’Donnell, Jr.
		 	Chief Executive Officer
		 	Date: October 13, 2006

  

					
		 		 	 xc: Hutchison & Mason PLLC
 3110 Edwards Mill
Road, Ste 100
 Raleigh, North Carolina 27612
 Attn: J. Robert
Taylor, IIIMutual Termination Agreement

 Exhibit 10.118 
 MUTUAL TERMINATION AGREEMENT 
 This Mutual Termination Agreement (this
“Agreement”) is dated October 25, 2006 (the “Effective Date” hereof) by and among Acheron Development Group, LLC, a California limited liability company (“Acheron”), Accentia, Inc., a Florida corporation
(“Accentia”), and TEAMM Pharmaceuticals, Inc. ., a Florida corporation (“TEAMM”). 
 WHEREAS, Acheron, Accentia
and TEAMM entered into a Distribution Agreement dated May 28, 2003 (the “Distribution Agreement”) pertaining to the 10/200 Product as defined therein; 
 WHEREAS, Acheron, Accentia and TEAMM have mutually agreed to terminate the Distribution Agreement. 
 NOW, THEREFORE, pursuant to Section 12.4 of the Distribution Agreement, Acheron, Accentia and TEAMM, for good and valuable consideration, including, without limitation, the elimination of the obligation of Accentia and TEAMM to make
certain future payments as set forth in Section 8 of the Distribution Agreement, the receipt, adequacy and sufficiency of which are hereby acknowledged, do hereby agree as follows: 
 1. Capital terms used herein that are not otherwise defined shall have the meanings as given to them in the Distribution Agreement 
 2. The Distribution Agreement is hereby terminated as of the Effective Date. For the avoidance of doubt, the effect of this termination is that all
rights to “sell” (as that word is defined in Section 3.1 of the Distribution Agreement) the 10/200 Product previously granted by Acheron to Accentia and TEAMM are being returned to and vested in Acheron, without any residual rights of
any kind remaining with Accentia and TEAMM. 
 3. Accentia and TEAMM hereby release Acheron, its officers, employees, directors,
agents and representatives from and against any and all claims, losses, damages, liabilities, demands, costs and expenses attributable to, or arising out of, in any way the Distribution Agreement. 
 4. Acheron hereby release Accentia and TEAMM, their officers, employees, directors, agents and representatives from and against any and all claims,
losses, damages, liabilities, demands, costs and expenses attributable to, or arising out of, in any way the Distribution Agreement. 
 5. This Agreement shall be governed and interpreted, and all rights and obligations of the parties shall be determined, in accordance with the laws of the State of California, without regard to its conflict of laws rules. All disputes
with respect to this Agreement, which cannot be resolved by good faith negotiation among the parties, shall be brought and heard either in the California State Courts located in Santa Clara County or the United States District Court for the Northern
District of California located in San Jose, California. The parties to this Agreement each consent to the in personam jurisdiction and 

  

 1 

 
venue of such courts. The parties agree that service of process upon them in any such action may be made if delivered in person, by courier service, by
facsimile or by certified mail, postage prepaid, return receipt requested, and shall be deemed effectively given upon confirmed receipt thereof. 
 6. This Agreement may be executed in two or three counterparts and any party hereto may execute any such counterpart, all of which when executed and delivered shall be deemed to be an original and to which all
counterparts, when fully executed by all of the parties, taken together shall constitute but one (1) and the same instrument. It shall not be necessary in making proof of this Agreement or any counterpart hereof to account for any other
counterpart except to the extent to show that another party signed and delivered the counterpart under which it is asserted to have certain responsibilities or obligations. 
 7. The Agreement states the entire agreement among the parties hereto about the termination of the Distribution Agreement, and supersedes all and all
prior agreements, commitments, communications, negotiations, offers (whether in writing or oral), representations, statements, understandings and writings pertaining thereto, and may not be amended or modified except by written instrument duly
executed and delivered by all of the parties hereto. 
 IN WITNESS WHEREOF, this Mutual Termination Agreement has been duly executed
and delivered by their duly authorized representatives to be effective as of the Effective Date. 
  

			
	Acheron Development Group, LLC
		
	By:	 	 /s/  Brian Smith

		 	 Brian Smith
  

	Date:	 	October 25, 2006
	
	Accentia Biopharmaceuticals, Inc.
	
	 /s/  Alan Pearce
 Alan Pearce

	Chief Financial Officer
	Date: October 25, 2006
	
	TEAMM Pharmaceuticals, Inc.
		
	By:	 	 /s/  Nicholas J. Leb

		 	Nicholas J. Leb
		 	Vice President, Finance
		 	Date: October 25, 2006

  

	
	xc: Hutchison & Mason PLLC
	3110 Edwards Mill Road, Suite 100
	Raleigh, North Carolina 27612
	 Attn: J. Robert Taylor, III

  

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