Document:

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                              AMENDED AND RESTATED

                         REGISTRATION RIGHTS AGREEMENT

                                     among

                      CARE MANAGEMENT SCIENCE CORPORATION

                            J. H. WHITNEY III, L.P.,

                     WHITNEY STRATEGIC PARTNERS III, L.P.,

                        FOUNDATION HEALTH SYSTEMS, INC.,

                               DAVID J. BRAILER,

                               RONALD A. PAULUS,

                                 BRENT MILNER,

                           ZEKE INVESTMENT PARTNERS,

                                      and

                              WILLIAM WINKENWERDER

                          -----------------------------
                           Dated as of October 2, 2000
                          -----------------------------

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                                TABLE OF CONTENTS

<TABLE>
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                                                                                                               Page
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1.       Definitions.............................................................................................1

2.       Securities Subject to this Agreement....................................................................4

         (a)      Registrable Securities.........................................................................4
         (b)      Holders of Registrable Securities..............................................................4

3.       Demand Registration.....................................................................................5

         (a)      Request for Demand Registration................................................................5
         (b)      Effective Demand Registration..................................................................5
         (c)      Expenses.......................................................................................5
         (d)      Underwriting Procedures........................................................................6
         (e)      Selection of Underwriters......................................................................6
         (f)      Limitations on Demand Registrations............................................................6

4.       Piggy-Back Registration.................................................................................7

         (a)      Piggy-Back Rights..............................................................................7
         (b)      Priority of Registrations......................................................................8
         (c)      Expenses.......................................................................................8
         (d)      Conditions and Limitations on Piggyback Registrations..........................................8

5.       Holdback Agreements.....................................................................................9

         (a)      Restrictions on Public Sale by Holders.........................................................9
         (b)      Restrictions on Public Sale by the Company.....................................................9

6.       Registration Procedures.................................................................................9

         (a)      Obligations of the Company.....................................................................9
         (b)      Seller Information............................................................................12
         (c)      Notice to Discontinue.........................................................................12
         (d)      Sale to Underwriter...........................................................................12

7.       Registration Expenses..................................................................................13

8.       Indemnification; Contribution..........................................................................13

         (a)      Indemnification by the Company................................................................13
         (b)      Indemnification by Holders....................................................................14
         (c)      Conduct of Indemnification Proceedings........................................................14

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                                TABLE OF CONTENTS
                                   (continued)

                                                                                                               Page

         (d)      Contribution..................................................................................15

9.       Rule 144; Other Exemptions.............................................................................16

10.      Certain Limitations on Registration Rights.............................................................16

11.      Miscellaneous..........................................................................................16

         (a)      Recapitalizations, Exchanges, etc.............................................................16
         (b)      No Inconsistent Agreements; Other Registration Rights.........................................16
         (c)      Remedies......................................................................................17
         (d)      Amendments and Waivers........................................................................17
         (e)      Notices.......................................................................................17
         (f)      Successors and Assigns........................................................................18
         (g)      Counterparts..................................................................................18
         (h)      Headings......................................................................................18
         (i)      Governing Law.................................................................................18
         (j)      Jurisdiction..................................................................................18
         (k)      Severability..................................................................................19
         (l)      Rules of Construction.........................................................................19
         (m)      Entire Agreement..............................................................................19
         (n)      Further Assurances............................................................................19

</TABLE>

                                    ii

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                          REGISTRATION RIGHTS AGREEMENT

                  THIS AMENDED AND RESTATED REGISTRATION RIGHTS AGREEMENT (the
"AGREEMENT"), dated as of October 2, 2000, among CARESCIENCE, INC., a
Pennsylvania corporation (the "COMPANY"), J. H. WHITNEY III, L.P., a Delaware
limited partnership ("JHW"), WHITNEY STRATEGIC PARTNERS III, L.P., a Delaware
limited partnership ("WSP", together with JHW, collectively referred to herein
as "WHITNEY") FOUNDATION HEALTH SYSTEMS, INC., a Delaware corporation ("FHS"),
DAVID J. BRAILER, RONALD A. PAULUS (David J. Brailer and Ronald A. Paulus
collectively referred to as the ("MANAGEMENT STOCKHOLDERS"), BRENT MILNER,
WILLIAM WINKENWERDER and ZEKE INVESTMENT PARTNERS, a Pennsylvania partnership
(Brent Milner, William Winkenwerder and Zeke Investment Partners collectively
referred to as the "INDIVIDUAL INVESTORS").

                  The parties hereto are parties to that certain Registration
Rights Agreement, dated as of December 28, 1998 (the "1998 AGREEMENT"), made in
connection with (i) the Stock Purchase Agreement (the "PURCHASE AGREEMENT"),
dated as of December 28, 1998, among the Company, Whitney and the Individual
Investors relating to the acquisition by Whitney and the Individual Investors of
an aggregate of 2,366,947 shares of Series C Convertible Preferred Stock, no par
value, of the Company (the "SERIES C CONVERTIBLE PREFERRED") for an aggregate
purchase price of $6,175,000.00 and (ii) the Exchange Agreement, dated as of the
date hereof, between FHS and the Company, pursuant to which FHS has agreed to
restructure its existing investment in the Company in return for 994,000 shares
of Series D Convertible Preferred Stock, no par value, of the Company (the
"SERIES D CONVERTIBLE PREFERRED"), 1,658,004 shares of Series E Convertible
Preferred Stock, no par value, of the Company (the "SERIES E CONVERTIBLE
PREFERRED") and 1,560,000 shares of Series G Redeemable Preferred Stock, no par
value, of the Company (the "SERIES G REDEEMABLE PREFERRED").

                  The parties hereto desire to amend and restate the 1998
Agreement to reflect certain changes to the capital structure of the Company and
certain other rights therein.

                  The parties hereby agree as follows:

                  1.       DEFINITIONS. As used in this Agreement, and unless
the context requires a different meaning, the following terms have the meanings
indicated:

                           "1998 AGREEMENT" has the meaning assigned such term
in the third paragraph of this Agreement.

                           "ACT" means the Securities Act of 1933, as amended,
and the rules and regulations of the SEC promulgated thereunder.

                           "APPROVED UNDERWRITER" has the meaning assigned such
term in Section 3(e).

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                           "APPROVED UNDERWRITER AMOUNT" has the meaning
assigned such term in Section 3(d).

                           "BUSINESS DAY" means any day other than a Saturday,
Sunday or other day on which commercial banks in the City of New York are
authorized or required by law or executive order to close.

                           "COMMON STOCK" means the Common Stock, no par value,
of the Company, or any other capital stock of the Company into which such stock
is reclassified or reconstituted.

                           "COMPANY UNDERWRITER" has the meaning assigned such
term in Section 4(a).

                           "DEMAND REGISTRATION" has the meaning assigned such
term in Section 3(a).

                           "DESIGNATED HOLDER" means Whitney, FHS, the
Management Stockholders, the Individual Investors and any of their respective
transferees to whom Registrable Securities have been transferred other than the
transferee to whom such securities have been transferred pursuant to a
registration statement under the Act or Rule 144 under the Act; provided, that,
for purposes of Section 3(a) hereof, the transferees of any Designated Holder
shall only be entitled to exercise that Designated Holder's Demand Registration
(if not already exercised by such Designated Holder) as a group.

                           "EXCHANGE ACT" means the Securities and Exchange Act
of 1934, as amended, and the rules and regulations of the SEC thereunder.

                           "HOLDER" has the meaning assigned such term in
Section 2(b).

                           "HOLDERS' COUNSEL" means (a) with respect to any
Demand Registration that has been requested pursuant to Section 3, the one
counsel selected by the Initiating Holder in such registration and (b) with
respect to a request for registration of Registrable Securities pursuant to
Section 4, the one counsel selected by the Holders holding a majority of the
Registrable Securities held by all Holders being registered in such
registration.

                           "INDEMNIFIED PARTY" has the meaning assigned such
term in Section 8(c).

                           "INDEMNIFYING PARTY" has the meaning assigned such
term in Section 8(c).

                           "INITIAL PUBLIC OFFERING" shall mean the sale in an
underwritten offering by the Company of its capital stock pursuant to a
registration statement on Form S-1 or otherwise under the Act.

                           "INITIATING HOLDER" has the meaning assigned to such
term in Section 3(a).

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                           "INSPECTOR" has the meaning assigned such term in
Section 6(a)(viii).

                           "NASD" has the meaning assigned such term in Section
6(a)(xv).

                           "PERSON" means any individual, firm, corporation,
partnership, trust, incorporated or unincorporated association, joint venture,
joint stock company, government (or an agency or political subdivision thereof)
or other entity of any kind, and shall include any successor (by merger or
otherwise) of any such entity.

                           "PURCHASE AGREEMENT" has the meaning assigned such
term in the second paragraph of this Agreement.

                           "REGISTRABLE SECURITIES" means, subject to
Section 2(a), each of the following: (a) any shares of Common Stock issued or
issuable upon conversion or in exchange for shares of the Series C Convertible
Preferred, Series D Convertible Preferred, Series E Convertible Preferred or
Series F Redeemable Preferred; (b) any shares of Common Stock held by the
Management Stockholders or any of their respective permitted transferees; and
(c) any shares of Common Stock issued or issuable in respect of shares of Common
Stock issued, issuable or held pursuant to clause (a) or (b) above by way of a
stock dividend or stock split or in connection with a combination of shares,
recapitalization, merger, consolidation or other reorganization or otherwise.

                           "REGISTRATION EXPENSES" has the meaning assigned such
term in Section 7.

                           "RULE 144" means Rule 144 under the Act (or any
similar rule adopted after the date hereof).

                           "SEC" means the Securities and Exchange Commission.

                           "SERIES C CONVERTIBLE PREFERRED" has the meaning
assigned such term in the second paragraph of this Agreement and is further
defined to include any other capital stock of the Company into which such stock
is reclassified or reconstituted.

                           "SERIES D CONVERTIBLE PREFERRED" means the Series D
Convertible Preferred Stock, no par value, of the Company (or any warrants to
purchase such stock), or any other capital stock of the Company into which such
stock is reclassified or reconstituted.

                           "SERIES E CONVERTIBLE PREFERRED" means the Series E
Convertible Preferred Stock, no par value, of the Company (or any warrants to
purchase such stock), or any other capital stock of the Company into which such
stock is reclassified or reconstituted.

                           "SERIES F REDEEMABLE PREFERRED" means the Series F
Redeemable Preferred Stock, no par value, of the Company (or any warrants to
purchase such stock), or any other capital stock of the Company into which such
stock is reclassified or reconstituted.

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                           "SERIES G REDEEMABLE PREFERRED" means the Series G
Redeemable Preferred, no par value, of the Company.

                           "SERIES PREFERRED" means, collectively, the Series C
Convertible Preferred, Series D Convertible Preferred, Series E Convertible
Preferred, Series F Redeemable Preferred and Series G Redeemable Preferred.

                           "SHARES" means the Common Stock, the Series
Preferred, any class of common stock of the Company authorized after the date of
this Agreement and any other class of stock resulting from successive changes or
reclassifications of the Shares.

                           "SHAREHOLDERS' AGREEMENT" means the Shareholders'
Agreement, dated the date hereof, among the Company, Whitney, FHS, the
Management Stockholders and the Individual Investors.

                           "TOTAL SECURITIES" has the meaning assigned such term
in Section 4(a).

                           "UNDERWRITERS" has the meaning assigned such term in
Section 6(d).

                           "VALID BUSINESS REASON" has the meaning assigned such
term in Section 3(f).

                           "WHITNEY DIRECTOR" means a person appointed by
Whitney to the Board of Directors of the Company pursuant to the Shareholders'
Agreement.

                  2.       SECURITIES SUBJECT TO THIS AGREEMENT.

                           (a)      REGISTRABLE SECURITIES.  For the purposes
of this Agreement, Registrable Securities will cease to be Registrable
Securities when (i) a registration statement covering such Registrable
Securities has been declared effective under the Act by the SEC and such
Registrable Securities have been disposed of pursuant to such effective
registration statement or (ii) the entire amount of Registrable Securities
proposed to be sold in a single sale are or, in the opinion of counsel
satisfactory to the Company and the Holder, each in their reasonable judgment,
may, be distributed to the public pursuant to Rule 144 in compliance with the
requirements of paragraphs (c), (e), (f) and (g) of Rule 144 (notwithstanding
the provisions of paragraph (k) of such Rule) (or any successor provision then
in effect) under the Act.

                           (b)      HOLDERS OF REGISTRABLE SECURITIES.  A
Person is deemed to be a holder of Registrable Securities (a "HOLDER") whenever
such Person (i) is a party to this Agreement (or a permitted transferee of such
party that has become a party hereto) and (ii) owns of record Registrable
Securities, or holds a security convertible into or exercisable or exchangeable
for, Registrable Securities, whether or not such purchase or conversion has
actually been effected and disregarding any legal restrictions upon the exercise
of such rights. If the Company receives conflicting instructions, notices or
elections from two or more persons with respect to the same Registrable
Securities, the Company may act upon the basis of the instructions, notice or
election received from the registered owner of such Registrable Securities.

                                       4
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Registrable Securities issuable upon conversion of another security shall be
deemed outstanding for the purposes of this Agreement.

                  3.       DEMAND REGISTRATION.

                           (a)      REQUEST FOR DEMAND REGISTRATION.  Subject
to Section 3(f) below, at any time after 6 months from the date of the
consummation of an Initial Public Offering, each of the Designated Holders
(other than the Individual Investors who, for purposes of this Section 3, shall
be deemed to be part of any Demand Registration in which Whitney is the
Initiating Holder) (each an "INITIATING HOLDER") shall have the right to make
one request in writing that the Company register Registrable Securities under
the Act, and under the securities or blue sky laws of any jurisdiction
designated by such holder or holders (each such registration under this Section
3(a) that satisfies the requirements set forth in Section 3(b) is referred to
herein as a "DEMAND REGISTRATION"); PROVIDED, HOWEVER, that the Management
Stockholders shall only be entitled to one demand right as a group.
Notwithstanding the foregoing, in no event shall the Company be required to
effect more than three Demand Registrations. Each request for a Demand
Registration by an Initiating Holder in respect thereof shall specify the amount
of the Registrable Securities proposed to be sold, the intended method of
disposition thereof and the jurisdictions in which registration is desired. Upon
a request for a Demand Registration, the Company shall promptly take such steps
as are necessary or appropriate to prepare for the registration of the
Registrable Securities to be registered. Within fifteen (15) days after the
receipt of such request, the Company shall give written notice thereof to all
other Designated Holders and include in such registration all Registrable
Securities held by a Designated Holder from whom the Company has received a
written request for inclusion therein at least ten (10) days prior to the filing
of the registration statement. Each such request will also specify the number of
Registrable Securities to be registered, the intended method of disposition
thereof and the jurisdictions in which registration is desired. Subject to
Section 3(d), the Company shall be entitled to include in any registration
statement and offering made pursuant to a Demand Registration, authorized but
unissued shares of Common Stock, shares of Common Stock held by the Company as
treasury shares or shares of Common Stock held by stockholders other than the
Designated Holders; PROVIDED, that such inclusion shall be permitted only to the
extent that it is pursuant to and subject to the terms of the underwriting
agreement or arrangements, if any, entered into by the Initiating Holder
exercising the Demand Registration rights.

                           (b)      EFFECTIVE DEMAND REGISTRATION.  The Company
shall use its best efforts to cause any Demand Registration to become effective
not later than ninety (90) days after it receives a request under Section 3(a).
A registration requested pursuant to Section 3(a) hereof shall not count as the
demand to which the Designated Holders are entitled thereunder unless such
registration statement is declared effective and remains effective for at least
the lesser of (i) such time as all Registrable Securities covered by such
registration statement have been disposed of in accordance with such
registration statement or (ii) ninety (90) days.

                           (c)      EXPENSES.  In any registration initiated as
a Demand Registration, the Company shall pay all Registration Expenses in
connection therewith, whether or not such requested Demand Registration becomes
effective.

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                           (d)      UNDERWRITING PROCEDURES.  If the Initiating
Holder to which the requested Demand Registration relates so elects, the
offering of such Registrable Securities pursuant to such requested Demand
Registration shall be in the form of a firm commitment underwritten offering and
the managing underwriter or underwriters selected for such offering shall be the
Approved Underwriter selected in accordance with Section 3(e). In such event, if
the Approved Underwriter advises the Company in writing that, in its opinion,
the aggregate amount of such Registrable Securities requested to be included in
such offering (including those securities requested by the Company to be
included in such registration) is sufficiently large to have an adverse effect
on the success of such offering, then the Company shall include in such
registration only the aggregate amount of Registrable Securities that in the
opinion of the Approved Underwriter may be sold without any such effect on the
success of such offering (the "APPROVED UNDERWRITER AMOUNT"), and (i) all
Registrable Securities that the Initiating Holder proposes to register
(including, in the case of Whitney, Registrable Securities held by the
Individual Investors) shall be included in the registration up to the Approved
Underwriter Amount, (ii) to the extent that the number of Registrable Securities
to be included by the Initiating Holder is less than the Approved Underwriter
Amount, securities proposed to be registered by the Designated Holders (other
than the Initiating Holder) shall be included ratably in the registration based
on the amounts of Registrable Securities sought to be registered by such
Designated Holders in their request for participation in the Demand Registration
and (iii) to the extent that the number of Registrable Securities to be included
under clauses (i) and (ii) above is less than the Approved Underwriter Amount,
securities that the Company proposes to register shall also be included in the
registration.

                           If, as a result of the proration provision of this
Section 3(d), any Designated Holder shall not be entitled to include all
Registrable Securities in a registration that such Designated Holder has
requested to be included in, such Designated Holder may elect to withdraw his
request to include Registrable Securities in such registration or may reduce the
number requested to be included; PROVIDED, HOWEVER, that (x) such request must
be made in writing prior to the earlier of the execution of the underwriting
agreement or the execution of the custody agreement with respect to such
registration and (y) such withdrawal or reduction shall be irrevocable.

                           (e)      SELECTION OF UNDERWRITERS.  If any requested
Demand Registration is in the form of an underwritten offering, the Initiating
Holder shall select and obtain an investment banking firm of national reputation
to act as the managing underwriter of the offering (the "APPROVED UNDERWRITER");
PROVIDED that such underwriter shall be reasonably satisfactory to a majority of
the Designated Holders (other than the Initiating Holders) and the Company.

                           (f)      LIMITATIONS ON DEMAND REGISTRATIONS.  The
Demand Registration rights granted to the Designated Holders in Section 3(a) are
subject to the following limitations: (i) each registration in respect of a
Demand Registration must include Registrable Securities having an aggregate
market value of at least [$5,000,000], which market value shall be determined by
multiplying the number of Registrable Securities to be included in the Demand
Registration by the proposed per share offering price; PROVIDED that the
limitation set forth in this clause (i) shall not be in effect at any time the
Designated Holders' Registrable Securities are not able to be sold under Rule
144 under the Act because of the Company's failure to comply with the
information requirements thereunder, unless at such time, the Company's outside
counsel

                                       6
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(which shall be reasonably acceptable to the Designated Holders requesting such
registration) delivers a written opinion of counsel to such Designated Holders
to the effect that such Designated Holders' Registrable Securities may be
publicly offered and sold without registration under the Act; (ii) the Company
shall not be required to cause a registration pursuant to Section 3(a) to be
declared effective within a period of 150 days after the effective date of any
registration statement of the Company effected in connection with a Demand
Registration; and (iii) if the Board of Directors of the Company, in its good
faith judgment, determines that any registration of Registrable Securities
should not be made or continued because it would materially interfere with any
material financing, acquisition, corporate reorganization or merger or other
transaction involving the Company or any of its subsidiaries (a "VALID BUSINESS
REASON"), the Company may (x) postpone filing a registration statement relating
to a Demand Registration until such Valid Business Reason no longer exists, but
in no event for more than ninety (90) days, and (y) in case a registration
statement has been filed relating to a Demand Registration, if the Valid
Business Reason has not resulted from actions taken by the Company, the Company,
upon the approval of a majority of the Company's Board of Directors, may cause
such registration statement to be withdrawn and its effectiveness terminated or
may postpone amending or supplementing such registration statement. The Company
shall give written notice of its determination to postpone or withdraw a
registration statement under Section 3(f)(iii) and of the fact that the Valid
Business Reason for such postponement or withdrawal no longer exists, in each
case, promptly after the occurrence thereof. Notwithstanding anything to the
contrary contained herein, the Company may not postpone or withdraw a filing
under Section 3(f)(iii) hereof more than once in any twelve-month period.

                           Each Holder of Registrable Securities agrees that,
upon receipt of any notice from the Company that the Company has determined to
withdraw any registration statement pursuant to clause (iii) above, such Holder
will discontinue its disposition of Registrable Securities pursuant to such
registration statement and, if so directed by the Company, will deliver to the
Company (at the Company's expenses) all copies, other than permanent file
copies, then in such Holder's possession, of the prospectus covering such
Registrable Securities that was in effect at the time of receipt of such notice.
If the Company shall give any notice of postponement or withdrawal of a
registration statement, the Company shall, at such time as the Valid Business
Reason that caused such postponement or withdrawal no longer exists (but in no
event later than ninety (90) days after the date of the postponement), use its
best efforts to promptly effect the registration under the Act of the
Registrable Securities covered by the postponed or withdrawn registration
statement in accordance with this Section 3 (unless the Designated Holder(s)
delivering the Demand Registration request shall have withdrawn such request, in
which case the Company shall not be considered to have effected an effective
registration for the purposes of this Agreement), and such registration shall
not be postponed or withdrawn pursuant to clause (iii) above.

                  4.       PIGGY-BACK REGISTRATION.

                           (a)      PIGGY-BACK RIGHTS.  If the Company proposes
to file a registration statement under the Act with respect to an offering by
the Company for its own account of any class of security (other than a
registration statement on Form S-4 or S-8 (or any successor form thereto)) under
the Act, then the Company shall give written notice of such proposed filing to
each of the Holders at least twenty (20) days before the anticipated filing
date, and such notice

                                       7
<PAGE>

shall describe in detail the proposed registration and distribution (including
those jurisdictions where registration under the securities or blue sky laws is
intended) and offer such Holders the opportunity to register the number of
Registrable Securities as each such Holder may request. The Company shall use
its best efforts (within ten (10) days of the notice provided for in the
preceding sentence) to permit the Holders who have requested to participate in
the registration for such offering to include such Registrable Securities in
such offering on the same terms and conditions as the securities of the Company
included therein. Notwithstanding the foregoing, if such registration involves
an underwritten offering and the managing underwriters or underwriters (the
"COMPANY UNDERWRITER") shall advise the Holders of Registrable Securities in
writing that, in its opinion, the total amount of securities requested to be
included in such offering (the "TOTAL SECURITIES") is sufficiently large so as
to have an adverse effect on the success of the distribution of the Total
Securities, then the Company shall include in such registration, to the extent
of the number of securities which the Company is so advised can be sold in (or
during the time of) such offering, FIRST, all securities that the Company
proposes to register, and, SECOND the securities proposed to be included in such
registration by all Holders pro rata among them, and, THIRD, all other
securities proposed to be registered. Notwithstanding anything in this Section 4
to the contrary, the Company shall not be required to include any Registrable
Securities in its Initial Public Offering.

                           (b)      PRIORITY OF REGISTRATIONS. Subject to the
provisions of Section 3(f)(iii), if the Company proposes to register securities
pursuant to Section 4(a) hereof on the same day that the Designated Holders
request a registration pursuant to Section 3(a) hereof, then the Demand
Registration requested pursuant to Section 3(a) hereof shall be given priority.

                           (c)      EXPENSES.  The Company shall bear all
Registration Expenses in connection with any registration pursuant to this
Section 4.

                           (d)      CONDITIONS AND LIMITATIONS ON PIGGYBACK
REGISTRATIONS. If, at any time after giving written notice of its intention to
register any securities and prior to the effective date of the registration
statement filed in connection with such registration, the Company shall
determine for any reason not to register or to delay registration of such
securities, the Company may, at its election, give written notice of such
determination to all Holders of record of Registrable Securities and (i) in the
case of a determination not to register, shall be relieved of its obligation to
register the Registrable Securities in connection with such abandoned
registration, without prejudice, however, to the rights of Holders under Section
3, and (ii) in the case of a determination to delay the registration of its
securities, shall be permitted to delay the registration of such Registrable
Securities for the same period as the delay in registering such other equity
securities.

                           Any Holder shall have the right to withdraw its
request for inclusion of its Registrable Securities in any registration
statement pursuant to this Section 4 by giving the written notice to the Company
of its request to withdraw; PROVIDED, HOWEVER, that (i) such request must be
made in writing prior to the earlier of the execution of the underwriting
agreement or the execution of the custody agreement with respect to such
registration and (ii) such withdrawal shall be irrevocable and, after making
such withdrawal, a Holder shall no longer have any right to include Registrable
Securities in the registration as to which such withdrawal was made.

                                       8
<PAGE>

                  5.       HOLDBACK AGREEMENTS.

                           (a)      RESTRICTIONS ON PUBLIC SALE BY HOLDERS. To
the extent not inconsistent with applicable law, each Holder agrees not to
effect any public sale or distribution of any Registrable Securities being
registered or of any securities convertible into or exchangeable or exercisable
for such Registrable Securities, including a sale pursuant to Rule 144 under the
Act, during the seven (7) days prior to or the ninety (90) day period beginning
on the effective date of such Demand Registration or Piggy-Back Registration or
other underwritten offering (except as part of such registration), if and to the
extent requested by any other Holder, in the case of a non-underwritten public
offering, or if and to the extent requested by the Company Underwriter, in the
case of an underwritten public offering. To the extent not inconsistent with
applicable law, each Holder also agrees that, during the period of duration (not
to exceed 180 days) specified by the Company and an underwriter of Common Stock
in connection with an Initial Public Offering, following the effective date of a
registration statement of the Company filed under the Act relating to such
Initial Public Offering, it shall not, to the extent requested by the Company
and such underwriter, directly or indirectly sell, offer to sell, contract to
sell (including, without limitation, any short sale), grant any option to
purchase or otherwise transfer or dispose of (other than to donees who agree to
be similarly bound) any securities of the Company held by it at any time during
such period (except Registrable Securities included in such registration).

                           (b)      RESTRICTIONS ON PUBLIC SALE BY THE COMPANY.
The Company agrees not to effect any public sale or distribution of any of its
securities for its own account (except pursuant to registrations on Form S-4 or
S-8 (or any successor form thereto) under the Act) during the ninety (90) day
period beginning on the effective date of any registration statement in which
the Holders are participating (except to the extent that such sale or
distribution is made pursuant to such registration).

                  6.       REGISTRATION PROCEDURES.

                           (a)      OBLIGATIONS OF THE COMPANY. Whenever
registration of Registrable Securities has been requested pursuant to Section 3
or 4 of this Agreement, the Company shall use its best efforts to effect the
registration and sale of such Registrable Securities in accordance with the
intended method of distribution thereof as quickly as practicable, and in
connection with any such request, the Company shall, as expeditiously as
possible:

                                    (i)     prepare and file with the SEC (in
any event not later than sixty (60) Business Days after receipt of a request to
file a registration statement with respect to Registrable Securities) a
registration statement on any form on which registration is requested for which
the Company then qualifies, which counsel for the Company and Holders' Counsel
shall deem appropriate and which shall be available for the sale of such
Registrable Securities in accordance with the intended method of distribution
thereof, and use its best efforts to cause such registration statement to become
effective; PROVIDED, HOWEVER, that before filing a registration statement or
prospectus or any amendments or supplements thereto, the Company shall (A)
provide Holders' Counsel with an adequate and appropriate opportunity to
participate in the preparation of such registration statement and each
prospectus included therein (and each

                                       9
<PAGE>

amendment or supplement thereto) to be filed with the SEC, which documents shall
be subject to the review of Holders' Counsel, and (B) notify Holders' Counsel
and each seller of Registrable Securities pursuant to such registration
statement of any stop order issued or threatened by the SEC and take all
reasonable action required to prevent the entry of such stop order or to remove
it if entered;

                                    (ii)    prepare and file with the SEC such
amendments and supplements to such registration statement and the prospectus
used in connection therewith as may be necessary to keep such registration
statement effective and to comply with the provisions of the Act with respect to
the disposition of all Registrable Securities covered by such registration
statement until the earlier of (a) such time as all of such Registrable
Securities and other securities have been disposed of in accordance with the
intended methods of disposition by the sellers thereof set forth in such
registration statement and (b) 180 days after the effective date of such
registration statement, except with respect to any such registration statement
filed pursuant to Rule 415 (or any successor Rule) under the Act if the Company
is eligible to file a registration statement on Form S-3, in which case such
period shall be two (2) years;

                                    (iii)   as soon as reasonably possible,
furnish to each seller of Registrable Securities, prior to filing a registration
statement, copies of such registration statement as it is proposed to be filed,
and thereafter such number of copies of such registration statement, each
amendment and supplement thereto (in each case including all exhibits thereto),
the prospectus included in such registration statement (including each
preliminary prospectus) and such other documents as each such seller may
reasonably request in order to facilitate the disposition of the Registrable
Securities owned by such seller;

                                    (iv)    use its best efforts to register
or qualify such Registrable Securities under such other securities or blue sky
laws of such jurisdictions as any seller of Registrable Securities may request,
and to continue such qualification in effect in each such jurisdiction for as
long as is permissible pursuant to the laws of such jurisdiction, or for as long
as any such seller requests or until all of such Registrable Securities are
sold, whichever is shortest, and do any and all other acts and things which may
be reasonably necessary or advisable to enable any such seller to consummate the
disposition in such jurisdictions of the Registrable Securities owned by such
seller; PROVIDED, HOWEVER, that the Company shall not be required to (A) qualify
generally to do business in any jurisdiction where it would not otherwise be
required to qualify but for this Section 6(a)(iv), (B) subject itself to
taxation in any such jurisdiction or (C) consent to general service of process
in any such jurisdiction;

                                    (v)     use its best efforts to obtain all
other approvals, covenants, exemptions or authorizations from such governmental
agencies or authorities as may be necessary to enable the sellers of such
Registrable Securities to consummate the disposition of such Registrable
Securities;

                                    (vi)    notify each seller of Registrable
Securities at any time when a prospectus relating thereto is required to be
delivered under the Act, upon discovery that, or upon the happening of any event
as a result of which, the prospectus included in such registration statement
contains an untrue statement of a material fact or omits to state any

                                       10
<PAGE>

material fact required to be stated therein or necessary to make the statements
therein not misleading in light of the circumstances under which they were made,
and the Company shall promptly prepare a supplement or amendment to such
prospectus and furnish to each such seller a reasonable number of copies of a
supplement to or amendment of such prospectus as may be necessary so that, after
delivery to the purchasers of such Registrable Securities, such prospectus shall
not contain an untrue statement of a material fact or omit to state any material
fact required to be stated therein or necessary to make the statements therein
not misleading in light of the circumstances under which they were made;

                                    (vii)   enter into and perform customary
agreements (including an underwriting agreement in customary form with the
Approved Underwriter or Company Underwriter, if any, selected as provided in
Section 3 or 4; PROVIDED, that the underwriting agreement, if any, shall be
reasonably satisfactory in form and substance to the Company) and take such
other actions as are reasonably required in order to expedite or facilitate the
disposition of such Registrable Securities;

                                    (viii)  make available for inspection by
any seller of Registrable Securities, any managing underwriter participating in
any disposition pursuant to such registration statement, Holders' Counsel and
any attorney, accountant or other agent retained by any such seller or any
managing underwriter (each, an "INSPECTOR" and, collectively, the "INSPECTORS"),
all financial and other records, pertinent corporate documents and properties of
the Company and any subsidiaries thereof as may be in existence at such time
(collectively, the "RECORDS") as shall be reasonably necessary to enable them to
exercise their due diligence responsibility, and cause the Company's and any
subsidiaries' officers, directors and employees, and the independent public
accountants of the Company, to supply all information reasonably requested by
any such Inspector in connection with such registration statement; PROVIDED,
that such Inspector agrees to keep all such information confidential.

                                    (ix)    obtain a "cold comfort" letter
from the Company's independent public accountants in customary form and covering
such matters of the type customarily covered by "cold comfort" letters, as
Holders' Counsel or the managing underwriter reasonably request;

                                    (x)     furnish, at the request of any
seller of Registrable Securities on the date such securities are delivered to
the underwriters for sale pursuant to such registration or, if such securities
are not being sold through underwriters, on the date the registration statement
with respect to such securities becomes effective, an opinion, dated such date,
of counsel representing the Company for the purposes of such registration,
addressed to the underwriters, if any, and to the seller making such request,
covering such legal matters with respect to the registration in respect of which
such opinion is being given as such seller may reasonably request and as are
customarily included in such opinions;

                                    (xi)    otherwise use its best efforts to
comply with all applicable rules and regulations of the SEC, and make available
to its security holders, as soon as reasonably practicable but no later than
fifteen (15) months after the effective date of the registration statement, an
earnings statement covering a period of twelve (12) months beginning

                                       11
<PAGE>

after the effective date of the registration statement, in a manner which
satisfies the provisions of Section 11(a) of the Act;

                                    (xii)    cause all such Registrable
Securities to be listed on each securities exchange on which similar securities
issued by the Company are then listed (if any) if the listing of such
Registrable Securities is then permitted under the rules of such exchange or, if
no similar securities are then so listed, cause all such Registrable Securities
to be listed on an exchange on which the Initiating Holders request that such
Registrable Securities be listed, subject to the satisfaction of the applicable
listing requirements of each such exchange;

                                    (xiii)  keep each seller of Registrable
Securities advised in writing as to the initiation and progress of any
registration under Section 3 or 4 hereunder;

                                    (xiv)   provide officers' certificates and
other customary closing documents;

                                    (xv)    cooperate with each seller of
Registrable Securities and each underwriter participating in the disposition of
such Registrable Securities and their respective counsel in connection with any
filings required to be made with the National Association of Securities Dealers,
Inc. (the "NASD"); and

                                    (xvi)    use its best efforts to take all
other steps necessary to effect the registration of the Registrable Securities
contemplated hereby.

                           (b)      SELLER INFORMATION. The Company may
require as a condition precedent of the Company's obligations under this Section
6 that each seller of Registrable Securities as to which any registration is
being effected furnish to the Company such information regarding such seller and
the distribution of such securities as the Company may from time to time
reasonably request in writing.

                           (c)      NOTICE TO DISCONTINUE. Each Holder agrees
that, upon receipt of any notice from the Company of the happening of any event
of the kind described in Section 6(a)(vi), such Holder shall forthwith
discontinue disposition of Registrable Securities pursuant to the registration
statement covering such Registrable Securities until such Holder's receipt of
the copies of the supplemented or amended prospectus contemplated by Section
6(a)(vi) and, if so directed by the Company, such Holder shall deliver to the
Company (at the Company's expense) all copies, other than permanent file copies
then in such Holder's possession, of the prospectus covering such Registrable
Securities which is current at the time of receipt of such notice. If the
Company shall give any such notice, the Company shall extend the period during
which such registration statement shall be maintained effective pursuant to this
Agreement (including, without limitation, the period referred to in Section
6(a)(ii)) by the number of days during the period from and including the date of
the giving of such notice pursuant to Section 6(a)(vi) to and including the date
when the Holder shall have received the copies of the supplemented or amended
prospectus contemplated by and meeting the requirements of Section 6(a)(vi).

                           (d)      SALE TO UNDERWRITER. Subject to the
limitations on inclusion of Registrable Securities in a registration under
Sections 3(d) and 4(a), in lieu of converting any

                                       12
<PAGE>

shares of Series C Convertible Preferred, Series D Convertible Preferred or
Series E Convertible Preferred into Registrable Securities to be included in a
registration under Section 3 or 4 prior to or simultaneously with the filing or
the effectiveness of any registration statement filed pursuant thereto, the
holder of such preferred stock may sell such stock to the Approved Underwriter
or the Company Underwriter, as the case may be, and any other underwriters of
the offering being registered (collectively, the Approved Underwriter or Company
Underwriter, as the case may be, and such other underwriters, the
"UNDERWRITERS") if the Underwriters consent thereto and if the Underwriters
undertake to convert such shares of Series C Convertible Preferred, Series D
Convertible Preferred or Series E Convertible Preferred into Registrable
Securities before making any distribution pursuant to such registration
statement and to include such Registrable Securities among the Registrable
Securities being offered pursuant to such registration statement. Assuming
timely delivery by the Holder of the Series C Convertible Preferred
certificates, Series D Convertible Preferred certificates or Series E
Convertible Preferred certificates to or for the account of the Underwriters,
the Company agrees to cause the relevant Registrable Securities to be issued so
as to permit the Underwriters to make and complete the distribution (including
the distribution of such Registrable Securities) contemplated by the
underwriting.

                  7. REGISTRATION EXPENSES. The Company shall pay all expenses
(other than underwriting discounts and commissions) arising from or incident to
the performance of, or compliance with, this Agreement, including, without
limitation, (a) SEC, stock exchange and NASD registration and filing fees, (b)
all fees and expenses incurred in complying with securities or blue sky laws
(including, without limitation, reasonable fees, charges and disbursements of
counsel in connection with blue sky qualifications of the Registrable
Securities), (c) all printing, messenger and delivery expenses, (d) the fees,
charges and disbursements of counsel to the Company and of its independent
public accountants and any other accounting and legal fees, charges and expenses
incurred by the Company (including, without limitation, any expenses arising
from any special audits incident to or required by any registration or
qualification) and (e) the reasonable fees, charges and expenses of any special
experts retained by the Company in connection with any requested Demand
Registration or Piggy-Back Registration pursuant to the terms of this Agreement,
regardless of whether the registration statement filed in connection with such
registration is declared effective. In connection with each registration
hereunder, the Company shall reimburse the Holders of Registrable Securities
being registered in such registration for the reasonable fees, charges and
disbursements of not more than one Holders' Counsel. All of the expenses
described in this Section 7 are referred to in this Agreement as "REGISTRATION
EXPENSES." Notwithstanding the foregoing provisions of this Section 7, in
connection with any registration hereunder, each Holder of Registrable
Securities being registered shall pay all underwriting discounts and commissions
and any capital gains, income or transfer taxes, if any, attributable to the
sale of such Registrable Securities, PRO RATA with respect to payments of
discounts and commissions in accordance with the number of shares sold in the
offering.

                  8.       INDEMNIFICATION; CONTRIBUTION.

                           (a)      INDEMNIFICATION BY THE COMPANY. In the
event of any proposed registration of securities of the Company pursuant to
Section 3 or Section 4, the Company agrees to indemnify and hold harmless each
Holder, its directors, officers, partners, employees, advisors and agents, and
each Person who controls (within the meaning of the Act or the Exchange Act)

                                       13
<PAGE>

such Holder, to the extent permitted by law, from and against any and all
losses, claims, damages, expenses (including, without limitation, reasonable
costs of investigation and fees, disbursements and other charges of counsel) or
other liabilities resulting from or arising out of or based upon any untrue, or
alleged untrue, statement of a material fact contained in any registration
statement, prospectus or preliminary prospectus or notification or offering
circular (as amended or supplemented if the Company shall have furnished any
amendments or supplements thereto) or arising out of or based upon any omission
or alleged omission to state therein a material fact required to be stated
therein or necessary to make the statements therein, in light of the
circumstances under which they were made, not misleading, except insofar as the
same are caused by or contained in any information furnished in writing to the
Company by or on behalf of such Holder expressly for use therein. The Company
shall also indemnify any Underwriters of the Registrable Securities, their
officers, directors and employees, and each Person who controls any such
Underwriter (within the meaning of the Act and the Exchange Act) to the same
extent as provided above with respect to the indemnification of the Holders of
Registrable Securities.

                           (b)      INDEMNIFICATION BY HOLDERS. In connection
with any proposed registration in which a Holder is participating pursuant to
Section 3 or 4 hereof, each such Holder shall furnish to the Company in writing
such information with respect to such Holder as the Company may reasonably
request or as may be required by law for use in connection with any registration
statement or prospectus to be used in connection with such registration and each
Holder agrees to indemnify and hold harmless the Company, any Underwriter
retained by the Company and their respective directors, officers, employees and
each Person who controls (within the meaning of the Act and the Exchange Act)
the Company or such Underwriter to the same extent as the foregoing indemnity
from the Company to the Holders (subject to the proviso to this sentence and
applicable law), but only with respect to any such information furnished in
writing by or on behalf of such Holder expressly for use therein; PROVIDED,
HOWEVER, that the liability of any Holder under this Section 8(b) shall be
limited to the amount of the net proceeds received by such Holder in the
offering giving rise to such liability.

                           (c)      CONDUCT OF INDEMNIFICATION PROCEEDINGS.
Any Person entitled to indemnification hereunder (the "INDEMNIFIED PARTY")
agrees to give prompt written notice to the indemnifying party (the
"INDEMNIFYING PARTY") after the receipt by the Indemnified Party of any written
notice of the commencement of any action, suit, proceeding or investigation or
threat thereof made in writing for which the Indemnified Party intends to claim
indemnification or contribution pursuant to this Agreement; PROVIDED, that the
failure so to notify the Indemnifying Party shall not relieve the Indemnifying
Party of any liability that it may have to the Indemnified Party hereunder. If
notice of commencement of any such action is given to the Indemnifying Party as
above provided, the Indemnifying Party shall be entitled to participate in and,
to the extent it may wish, jointly with any other Indemnifying Party similarly
notified, to assume the defense of such action at its own expense, with counsel
chosen by it and satisfactory to such Indemnified Party. The Indemnified Party
shall have the right to employ separate counsel in any such action and
participate in the defense thereof, but the fees and expenses of such counsel
(other than reasonable costs of investigation) shall be paid by the Indemnified
Party unless (i) the Indemnifying Party agrees to pay the same, (ii) the
Indemnifying Party fails to assume the defense of such action with counsel
satisfactory to the Indemnified Party in its reasonable judgment, (iii) the
named parties to any such action (including any impleaded parties) have been

                                       14
<PAGE>

advised by the Indemnifying Party's counsel that either (A) representation of
such Indemnified Party and the Indemnifying Party by the same counsel would be
inappropriate under applicable standards of professional conduct or (B) there
may be one or more legal defenses available to it which are different from or
additional to those available to the Indemnifying Party; PROVIDED, HOWEVER, that
the Indemnifying Party shall only have to pay the fees and expenses of one firm
of counsel for all Indemnified Parties in each jurisdiction, except to the
extent representation of all Indemnified Parties by the same counsel is
inappropriate under applicable standards of professional conduct. In either of
such cases the Indemnifying Party shall not have the right to assume the defense
of such action on behalf of such Indemnified Party. No Indemnifying Party shall
be liable for any settlement entered into without its written consent, which
consent shall not be unreasonably withheld. No Indemnifying Party shall, without
the written consent of the Indemnified Party, effect the settlement or
compromise of, or consent to the entry of any judgment with respect to, any
pending or threatened action or claim in respect of which indemnification or
contribution may be sought hereunder (whether or not the Indemnified Party is an
actual or potential party to such action or claim) unless such settlement,
compromise or judgment (A) includes an unconditional release of the Indemnified
Party from all liability arising out of such action or claim and (B) does not
include a statement as to or an admission of fault, culpability or a failure to
act, by or on behalf of any Indemnified Party. The rights accorded to any
Indemnified Party hereunder shall be in addition to any rights that such
Indemnified Party may have at common law, by separate agreement or otherwise.

                           (d)      CONTRIBUTION. If the indemnification
provided for in Section 8(a) from the Indemnifying Party is unavailable to an
Indemnified Party in respect of any losses, claims, damages, expenses or other
liabilities referred to therein, then the Indemnifying Party, in lieu of
indemnifying such Indemnified Party, shall contribute to the amount paid or
payable by such Indemnified Party as a result of such losses, claims, damages,
expenses or other liabilities in such proportion as is appropriate to reflect
the relative fault of the Indemnifying Party and Indemnified Party in connection
with the actions which resulted in such losses, claims, damages, expenses or
other liabilities, as well as any other relevant equitable considerations. The
relative faults of such Indemnifying Party and Indemnified Party shall be
determined by reference to, among other things, whether any action in question,
including any untrue or alleged untrue statement of a material fact or omission
or alleged omission to state a material fact, was made by, or relates to
information supplied by, such Indemnifying Party or Indemnified Party, and the
Indemnifying Party's and Indemnified Party's relative intent, knowledge, access
to information and opportunity to correct or prevent such action. The amount
paid or payable by a party as a result of the losses, claims, damages, expenses
or other liabilities referred to above shall be deemed to include, subject to
the limitations set forth in Sections 8(a), 8(b) and 8(c), any legal or other
fees, charges or expenses reasonably incurred by such party in connection with
any investigation or proceeding.

         The parties hereto agree that it would not be just and equitable if
contribution pursuant to this Section 8(d) were determined by pro rata
allocation or by any other method of allocation which does not take account of
the equitable considerations referred to in the immediately preceding paragraph.
No person guilty of fraudulent misrepresentation (within the meaning of Section
11(f) of the Act) shall be entitled to contribution pursuant to this Section
8(d).

                                       15
<PAGE>

                  9. RULE 144; OTHER EXEMPTIONS. If the Company shall have filed
a registration statement pursuant to the requirements of Section 12 of the
Exchange Act or a registration statement pursuant to the requirements of the Act
in respect of Common Stock or securities of the company convertible into or
exchangeable or exercisable for Common Stock, the Company covenants that it
shall file any reports required to be filed by it under the Exchange Act and the
rules and regulations adopted by the SEC thereunder, and that it shall take such
further action as each Holder may reasonably request (including, but not limited
to, providing any information necessary to comply with Rules 144 and 144A under
the Act), all to the extent required from time to time to enable such Holder to
sell Registrable Securities without registration under the Act within the
limitation of the exemptions provided by (a) Rule 144 or Rule 144A under the
Act, as such rules may be amended from time to time, or (b) any other rules or
regulations now existing or hereafter adopted by the SEC. The Company shall,
upon the request of any Holder, deliver to such Holder a written statement as to
whether the Company has complied with such requirements.

                 10. CERTAIN LIMITATIONS ON REGISTRATION RIGHTS. In the case of
a registration under Section 4 if the Company has determined to enter into an
underwriting agreement in connection therewith, no person may participate in
such registration unless such person (a) agrees to sell such person's securities
on the basis provided therein and (b) completes and executes all questionnaires,
powers of attorney, indemnities, lock-up agreements, underwriting agreements and
other documents reasonably required under the terms of such underwriting
agreements.

                 11.       MISCELLANEOUS.

                           (a)      RECAPITALIZATIONS, EXCHANGES, ETC.  The
provisions of this Agreement shall apply, to the full extent set forth herein
with respect to the Shares, to any and all shares of capital stock of the
Company or any successor or assign of the Company (whether by merger,
consolidation, sale of assets or otherwise) which may be issued in respect of,
in exchange for or in substitution of, the Shares and shall be appropriately
adjusted for any stock dividends, splits, reverse splits, combinations,
recapitalizations and the like occurring after the date hereof.

                           (b)      NO INCONSISTENT AGREEMENTS; OTHER
REGISTRATION RIGHTS. The Company shall not enter into any agreement with respect
to its securities that is inconsistent with or adversely affects the rights
granted to the Holders in this Agreement other than any lock-up agreement with
the underwriters in connection with an underwritten offering pursuant to which
the Company agrees, for a period not in excess of 180 days if such underwritten
offering is an Initial Public Offering or, for a period not in excess of 90 days
if such underwritten offering is not an Initial Public Offering, not to register
for sale, and not to sell or otherwise dispose of, Common Stock or any
securities convertible into or exercisable or exchangeable for Common Stock. The
Company shall not grant any other Person registration rights with terms and
conditions more favorable to such holder than the terms and conditions
applicable to the Designated Holders herein without the written consent of the
Designated Holders holding at least a majority of the Registrable Securities
held by all of the Designated Holders. If the Company shall at any time
hereafter provide to any holder of any securities of the Company rights with
respect to the registration of such securities and such rights are provided on
terms or conditions

                                       16
<PAGE>

more favorable to such holder than the terms and conditions applicable to the
Designated Holders herein, the Company shall provide (by way of amendment to
this Agreement or otherwise) such more favorable terms or conditions to the
Designated Holders under this Agreement.

                           (c)      REMEDIES. The Holders, in addition to
being entitled to exercise all rights granted by law, including recovery of
damages, shall be entitled to specific performance of their rights under this
Agreement. The Company agrees that monetary damages would not be adequate
compensation for any loss incurred by reason of a breach by it of the provisions
of this Agreement and hereby agrees to waive in any action for specific
performance the defense that a remedy at law would be adequate.

                           (d)      AMENDMENTS AND WAIVERS. Except as
otherwise provided herein, the provisions of this Agreement may not be amended,
modified or supplemented, and waivers or consents to departures from the
provisions of such section may not be given unless the Company has obtained the
prior written consent of (i) the Designated Holders holding at least a majority
of the Registrable Securities held by all of the Designated Holders and (ii) the
Holders holding at least a majority of the Registrable Securities.

                           (e)      NOTICES. All notices, demands and other
communications provided for or permitted hereunder shall be made in writing and
shall be by registered or certified first-class mail, return receipt requested,
telecopier, courier service or personal delivery:

                    (i)     if to Whitney or the Individual Investors:

                                     c/o J. H. Whitney & Co.
                                     177 Broad Street
                                     Stamford, Connecticut 06901
                                     Telecopier No.:  (203) 973-1422
                                     Attention:  Jeffrey R. Jay, M.D.

                                     with a copy to:

                                     Paul, Weiss, Rifkind, Wharton & Garrison
                                     1285 Avenue of the Americas
                                     New York, New York 10019-6064
                                     Telecopier No.: (212) 757-3990
                                     Attention:  Bruce A. Gutenplan, Esq.

                   (ii)     if to FHS:

                                     Foundation Health Systems, Inc.
                                     21600 Oxnard Street, Suite 2000
                                     Woodland Hills, CA 91367
                                     Telecopier No.:  (818) 676-7503
                                     Attention:  Michael E. Jansen

                                       17
<PAGE>

                  (iii)     if to the Company:

                                     CareScience, Inc.
                                     3600 Market Street, 6th Floor
                                     Philadelphia, PA 19104
                                     Telecopier No.:  (215) 387-9406
                                     Attention:  Chief Executive Officer

                            with a copy to:

                                     Morgan, Lewis & Bockius
                                     1701 Market Street
                                     Philadelphia, PA 19103
                                     Telecopier No.:  (215) 963-5299
                                     Attention:  Stephen M. Goodman

                   (iv)    if to an Existing Shareholder, to its, his or her
address as it appears on the record books of the Company.

                  All such notices and communications shall be deemed to have
been duly given: when delivered by hand, if personally delivered; when delivered
by courier, if delivered by commercial overnight courier service; five Business
Days after being deposited in the mail, postage prepaid, if mailed; and when
receipt is acknowledged, if telecopied.

                           (f)      SUCCESSORS AND ASSIGNS. This Agreement
shall inure to the benefit of and be binding upon the successors and assigns of
the parties hereto; PROVIDED, HOWEVER, that the registration rights and the
other obligations of the Company contained in this Agreement shall, with respect
to any Registrable Security, be automatically transferred from a Holder to any
subsequent holder of such Registrable Security (including any pledgee).
Notwithstanding any transfer of such rights, all of the obligations of the
Company hereunder shall survive any such transfer and shall continue to inure to
the benefit of all transferees.

                           (g)      COUNTERPARTS. This Agreement may be
executed in any number of counterparts and by the parties hereto in separate
counterparts, each of which when so executed shall be deemed to be an original
and all of which taken together shall constitute one and the same agreement.

                           (h)      HEADINGS. The headings in this Agreement
are for convenience of reference only and shall not limit or otherwise affect
the meaning hereof.

                           (i)      GOVERNING LAW. This Agreement shall be
governed by and construed in accordance with the laws of the Commonwealth of
Pennsylvania, without regard to the principles of conflicts of law of such
State.

                           (j)      JURISDICTION. Each party to this Agreement
hereby irrevocably agrees that any legal action or proceeding arising out of or
relating to this Agreement or any

                                       18
<PAGE>

agreements or transactions contemplated hereby may be brought in the courts of
the State of New York or of the United States of America for the Southern
District of New York and hereby expressly submits to the personal jurisdiction
and venue of such courts for the purposes thereof and expressly waives any claim
of improper venue and any claim that such courts are an inconvenient forum. Each
party hereby irrevocably consents to the service of process of any of the
aforementioned courts in any such suit, action or proceeding by the mailing of
copies thereof by registered or certified mail, postage prepaid, to the address
set forth in Section 10(e), such service to become effective 10 days after such
mailing.

                           (k)      SEVERABILITY. If any one or more of the
provisions contained herein, or the application thereof in any circumstance, is
held invalid, illegal or unenforceable in any respect for any reason, the
validity, legality and enforceability of any such provision in every other
respect and of the remaining provisions hereof shall not be in any way impaired,
it being intended that all of the rights and privileges of the Holders shall be
enforceable to the fullest extent permitted by law.

                           (l)      RULES OF CONSTRUCTION. Unless the context
otherwise requires, "or" is not exclusive, and references to sections or
subsections refer to sections or subsections of this Agreement.

                           (m)      ENTIRE AGREEMENT. This Agreement is
intended by the parties as a final expression of their agreement and intended to
be a complete and exclusive statement of the agreement and understanding of the
parties hereto in respect of the subject matter contained herein. There are no
restrictions, promises, warranties or undertakings in respect of the subject
matter contained herein, other than those set forth or referred to herein. This
Agreement supersedes all prior agreements and understandings between the parties
with respect to such subject matter.

                           (n)      FURTHER ASSURANCES.  Each of the parties
shall execute such documents and perform such further acts as may be reasonably
required or desirable to carry out or to perform the provisions of this
Agreement.

                                       19
<PAGE>

         IN WITNESS WHEREOF, the undersigned have caused this Agreement to be
executed and delivered by their respective officers hereunto duly authorized on
the date first above written.

                              CARESCIENCE, INC.

                           By    /s/ David J. Brailer
                                -------------------------------------
                                Name:  David J. Brailer
                                Title: Chief Executive Officer

                           J.H. WHITNEY III, L.P.

                           By          J.H. Whitney Equity Partners III, L.L.C.
                                       Its General Partner

                           By    /s/ Daniel J. O'Brien
                                -------------------------------------
                                Name:  Daniel J. O'Brien
                                       Managing Member

                           WHITNEY STRATEGIC PARTNERS III, L.P.

                           By          J.H. Whitney Equity Partners III, L.L.C.
                                       Its General Partner

                           By    /s/ Daniel J. O'Brien
                                -------------------------------------
                                Name: Daniel J. O'Brien
                                      Managing Member

                           FOUNDATION HEALTH SYSTEMS, INC.

                           By
                                -------------------------------------
                                Name:
                                Title:

                                 20
<PAGE>

                           ZEKE INVESTMENT PARTNERS

                           By    /s/ Edward N. Antoian
                                -------------------------------------
                                Name:  Edward N. Antoian
                                Title: General Partner

                            /s/ David J. Brailer
                           ------------------------------------------
                           David J. Brailer

                            /s/ Ronald A. Paulus
                           ------------------------------------------
                           Ronald A. Paulus

                            /s/ Brent Milner
                           ------------------------------------------
                           Brent Milner

                            /s/ William Winkenwerder
                           ------------------------------------------
                           William Winkenwerder

                                       21<PAGE>

                                LICENSE AGREEMENT

                                 by and between

                        CALIFORNIA HEALTHCARE FOUNDATION

                                       and

                                CARESCIENCE, INC.
                 (Formerly Care Management Science Corporation)

                           Dated as of October 2, 2000

<PAGE>

         This LICENSE AGREEMENT (the "Agreement") is made as of the 2nd day of
October, 2000 between the California Healthcare Foundation, a nonprofit public
benefit corporation ("CHCF") and CareScience, Inc., a corporation organized and
existing under the laws of the Commonwealth of Pennsylvania ("Licensee").

                  The Effective Date is October 1, 1999.

WHEREAS CHCF and Licensee are parties to that certain Consulting Agreement,
dated as of October 1, 1999 (the "Consulting Agreement"), pursuant to which CHCF
engaged Licensee to perform certain services as set forth therein; and

WHEREAS Section 9 of the Consulting Agreement provides for the ownership rights
and use of certain intellectual property developed in connection with the
Project (as defined in the Consulting Agreement); and

WHEREAS Section 9 of the Consulting Agreement provides that CHCF grants to
Licensee a fully-paid, non exclusive, perpetual, worldwide license to certain
intellectual property; and

WHEREAS Licensee desires to obtain from CHCF an exclusive license to use the
Licensed Work (as defined herein), subject to the terms, conditions and
provisions hereinafter set forth; and

WHEREAS CHCF and Licensee desire that the subject matter of this Agreement
supersede Section 9 of the Consulting Agreement;

NOW, THEREFORE in consideration of the premises and of the promises and mutual
covenants contained herein, and intending to be legally bound hereby, the
parties hereto agree as follows:

                                    ARTICLE I
                                   DEFINITIONS

                  The following terms, as used herein, shall have the following
                  meanings:

                  "Affiliate" means any Person directly or indirectly
controlling, controlled by or under common control with Licensee. For purposes
of this Agreement, "control" means the direct or indirect ownership of over 50%
of the outstanding voting securities of a Person, or the right to receive over
50% of the profits or earnings of a Person, or the right to control the policy
decisions of a Person.

                  "Bankruptcy Event" means the Person in question becomes
insolvent, or voluntary or involuntary proceedings by or against such Person are
instituted in bankruptcy or under any insolvency law, or a receiver or custodian
is appointed for such Person, or proceedings are instituted by or against such
Person for corporate

<PAGE>

reorganization or the dissolution of any such Person, which
proceedings, if involuntary, shall not have been dismissed within ninety (90)
days after the date of filing, or such Person makes an assignment for the
benefit of creditors, or substantially all of the assets of such Person are
seized or attached and not released within sixty (60) days thereafter.

                  "Calendar Quarter" means each three-month period, or any
portion thereof, beginning on January 1, April 1, July 1 and October 1.

                  "Care Data Exchange Project IP" means any and all IP used in,
developed during, or related to the data exchange project funded by CHCF (the
"Data Exchange Project"), which is a project to develop (i) concepts related to,
(ii) a methodology for, and (iii) means of effecting the electronic distribution
and sharing or exchange of data through a site or sites located on the world
wide web, which data may consist of text, graphics, still or moving images,
audio files, e-mail or other content.

                  "CHCF Intellectual Property" means any and all IP which is
either Care Data Exchange Project IP or Vendor Certification Project IP and not
(i) data which solely identifies a specific individual or entity, (ii) a
standard software product (i.e., a product generally available for license to
consumers (e.g., "Windows" or "Quicken" products)) licensed or purchased in the
ordinary course of business or (iii) a software product set forth in a schedule
to either a Final Anchor Agreement (as defined in the Consulting Agreement) or a
Care Data Alliance Agreement (as defined in a Final Anchor Agreement) which is
solely an internal system or process of a Care Alliance Anchor (as defined in
the Consulting Agreement) or a member of a Care Alliance (as defined in the
Consulting Agreement) (i.e. not necessary to the functioning of any work
included in the Care Data Exchange Project IP or the Vendor Certification
Project IP).

                  "Confidential Information" means and includes (i) the Licensed
Work, (ii) any other information or material in tangible form that is marked as
confidential or proprietary by the furnishing party at the time it is delivered
to the receiving party, and (iii) information that is furnished orally if the
furnishing party identifies such information as confidential or proprietary when
it is disclosed and promptly confirms such designation in writing after such
disclosure.

                  "Copyright" means the copyrights related to the Licensed Work,
including the copyright applications and registration(s), if any, authorized
under Title 17 of the United States Code or under the laws of any other
jurisdiction.

                  "Customer" means any Person who has executed a valid End User
Agreement, Distributor Sublicense Agreement or any other form of sublicense
agreement approved by CHCF relating to the license set forth herein.

                  "Distributor Sublicense Agreement" means an agreement between
Licensee and a Person granting the right to use or benefit from any of the
rights granted hereinunder in the form of a Distributor Sublicense in
substantially the form agreed to pursuant to Section 2.1(c).

                                       2
<PAGE>

                  "Distributor Sublicense" means a sublicense granted by
Licensee to a third party which allows that third party to modify software, and
sublicense that software in the form of End-User Sublicenses only.

                  "End User Agreement" means an agreement between Licensee and a
Person granting the right to use or benefit from any of the rights granted
hereinunder in the form of an End User Sublicense in substantially the form
agreed to pursuant to Section 2.1(c).

                  "End User Sublicense" means a sublicense granted by Licensee
 which allows the sublicensee to use, but not to modify or to distribute
 software.

                  "Fees" shall mean, cumulatively, Service Fees and Sublicense
Fees. Licensee shall establish: 1) stand-alone Sublicense Fees and 2) Service
Fees for use, maintenance or modification of the Licensed Work. If Licensee
charges a Customer Service Fees for a package of services, only some of which
involves use of the Licensed Program, and no volume or other Customer discount
is provided, then the portion of Licensee's revenues representing Fees shall not
be less than the separate prices or Fees charged by Licensee on a stand-alone
basis for services using the Licensed Work. If Licensee charges a Customer
service Fees on such a package of services and a volume or other discount is
provided, then the discount related to use of the Licensed Work shall be no
greater than the discount related to other services provided by Licensee. CHCF
acknowledges that Licensee also may have to negotiate Sublicense Fee discounts
from its published fees in the usual course of doing business.

                  Licensee shall be permitted to deduct from Fees qualifying
costs directly attributable to the sublicensing of the Licensed Work, which are
actually identified on the invoice and borne by Licensee, or the provision of
services using the Licensed Work, which are actually identified on the invoice
and borne by Licensee or its sublicensee.

                  Such qualifying costs shall be limited to the following:

         (i)      Discounts, in amounts customary in the trade, for quantity
         purchases, prompt payments and for wholesalers and distributors;

         (ii)     Credits or refunds, not exceeding the original invoice amount,
         for claims or returns;

         (iii)    Prepaid transportation insurance amounts;

         (iv)     Prepaid outbound transportation expenses;

         (v)      Sales and use taxes imposed by a government agency upon
         Licensee; and

                                       3
<PAGE>

         (vi)     Permitted Proprietary Rights Fees (as defined in Section
         8.1(a)).

                  "IP" means any and all business models, copyrights, data,
software, technical and other documentation, trade secret rights (including any
that may be included in any patent applications), and all other intellectual
property rights as may now exist or hereafter come into existence and be
protectable by law anywhere throughout the world, and all applications and
registrations therefor, patent rights, and name, brand, mark trademark, service
mark, trade dress, business name or other indicia of origin including without
limitation any registrations, applications and renewals therefor.

                  "Licensed Work" means the CHCF Intellectual Property, and any
portion or Modification thereof.

                  "Modification" of a work means any and all changes including
improvements, enhancements, corrections, revisions to the work or any portion
thereof, and any derivative of or work substantially similar to any of the
foregoing, made by CHCF or Licensee (or any licensee or distributor of
Licensee).

                  "Person" or "Persons" means any corporation, partnership,
joint venture or natural person.

                  "Safety Net Provider" means any governmental entity
(including, without limitation, local or state governments and similar
governmental entities) that provides health care services, or other provider
(including non-profit and for-profit hospitals) of health care services whose
primary purpose is to provide health care to persons who cannot otherwise afford
to pay for such services

                  "Sale" as applied to the Licensed Work means a genuine, BONA
FIDE transaction for which consideration is received or expected for the use,
maintenance, modification, lease, transfer or any other disposition of the
Licensed Work. A Sale of the Licensed Work shall be deemed completed at the time
Licensee or its sublicensee invoices, ships, or receives payment for such
Licensed Work, whichever occurs first.

                  "Service Fees" means gross consideration actually received by
Licensee as a fee for use of the Licensed Work (including, without limitation,
any maintenance, modification or similar services related to the Licensed Work).
CHCF hereby acknowledges that Licensee has in the past and will continue to
provide consulting, other products and other product-related services to third
parties which do not employ the use of, or involve maintenance, modification or
similar services related to the Licensed Work, and CHCF further acknowledges
that such revenues are expressly not a part of Service Fees as defined herein.

                  "Sublicense Fees" means gross consideration actually received
by Licensee (i) as a fee for sublicensing the Licensed Work to any third party
or (ii) as royalties under the terms of any such sublicense agreement.

                                       4
<PAGE>

                  "Vendor Certification Project IP" means any and all IP used
in, developed during, or related to the vendor certification project funded by
CHCF, which is a project to develop (i) concepts related to, (ii) a methodology
for, and (iii) means of effecting the electronically-enabled application for
certification of vendors or suppliers of goods or services to be used in
connection with the Data Exchange Project or any similar data exchange project
("Project Vendors"), certification of Project Vendors, promulgation of Project
Vendor standards, distribution of tools and/or information about tool sets
required for Project Vendor certification, and to display Project Vendors'
certification status and results.

                                   ARTICLE II
                                GRANT OF LICENSE

         2.1 GRANT OF LICENSE. Subject to the terms and conditions contained in
this Agreement, CHCF hereby grants to Licensee for the term of this Agreement a
royalty-bearing, worldwide, exclusive license, with a right to sublicense to:

         (a) make copies of, to make derivative works of, and to use the
         Licensed Work;

         (b) distribute the Licensed Work;

         (c) sublicense the Licensed Work (as either an End User Sublicense or a
         Distributor Sublicense) to Customers of Licensee who have first
         executed an End User Agreement or a Distributor Sublicense Agreement,
         as the case may be. The terms and conditions of a form of End User
         Agreement and Distributor Sublicense Agreement shall be reasonably
         agreed upon by both CHCF and Licensee.

         2.2 NO RIGHTS BY IMPLICATION. No rights or licenses with respect to the
Licensed Work are granted or deemed granted hereunder or in connection herewith,
other than those rights or licenses expressly granted in this Agreement.

                                   ARTICLE III
                                  COMPENSATION

         3.1 ROYALTIES.

         (a) In consideration for the license granted by this Agreement,
         Licensee shall pay CHCF royalties as follows on all Sales of the
         Licensed Work:

                                       5
<PAGE>

                  (i)       [*];

                  (ii)      [*];

         (b) In the event CHCF releases a Modification to the Licensed program
         developed exclusively by CHCF, CHCF shall be entitled to a royalty of
         [*] of the Sublicense Fee paid by existing Customers for such
         modification. In the event that such a Modification is jointly
         developed by CHCF and Licensee, Licensee shall pay a royalty to CHCF
         equal to a prorated percentage of [*] based upon the relative
         contributions of the two parties, such contributions to be mutually
         agreed upon.

         (c) Notwithstanding the foregoing, Licensee shall not be required to
         make a payment hereunder until the earlier of (i) June 30, 2001 and
         (ii) the date on which CHCF has earned Fees equal to or in excess of
         $10,000 (the "Transition Period").

         3.2 MINIMUM ROYALTIES. Licensee shall Pay to Licensor minimum annual
royalties ("Minimum Royalties") for the following periods in the corresponding
amounts:

                                         CALENDAR YEAR BEGINNING

                 Transition Period         January 1, 2000
                 $25,000.                  January 1, 2001
                 $41,250.                  January 1, 2002
                 $57,500.                  January 1, 2003
                 $73,750.                  January 1, 2004
                 $90,000.                  January 1, 2005 and for
                                             each calendar year thereafter

Licensee shall pay these Minimum Royalties in four (4) evenly distributed
installments on the last day of each calendar quarter (March 31, June 30,
September 30 and December 31) of each year.

           3.3 EXCLUSIVE; NON-EXCLUSIVE LICENSE. If Licensee fails to pay the
Minimum Royalties as set forth in section 3.2 above for any calendar year, CHCF
will have the right in its sole discretion on written notice to Licensee
delivered at any time after the end of such calendar year, to convert the
license granted hereunder from an exclusive to a non-exclusive license.

---------------------
*WE ARE SEEKING CONFIDENTIAL TREATMENT OF THESE TERMS, WHICH HAVE BEEN
OMITTED. THE CONFIDENTIAL PORTIONS HAVE BEEN FILED SEPARATELY WITH THE
SECURITIES AND EXCHANGE COMMISSION.

                                       6
<PAGE>

          3.4 PAYMENTS. Royalties payable under Section 3.1 hereof shall be paid
within forty-five (45) days following the last day of the Calendar quarter in
which the royalties accrue. The final payment shall be made within thirty (30)
days after termination of this Agreement. Royalties shall be deemed paid as of
the day on which they are received at the account designated pursuant to Section
3.6. Royalties that are not paid when due shall be subject to interest in
accordance with Section 3.6 hereof.

          3.5 REPORTS. Licensee shall deliver to CHCF within forty-five (45)
days after the end of each Calendar Quarter a report, certified by the chief
financial officer of Licensee, setting forth in reasonable detail the
calculation of the earned royalties and Minimum Royalties available for credit
payable to CHCF for such Calendar Quarter.

          3.6      CURRENCY. PLACE OF PAYMENT INTEREST.

         (a) CURRENCY; PLACE OF PAYMENT. All dollar amounts referred to in this
         Agreement are expressed in United States dollars. All payments of
         Royalties and other amounts to CHCF under this Agreement shall be made
         in United States dollars (or other legal currency of the United States)
         by check payable to "California Healthcare Foundation".

         (b) INTEREST. Amounts that are not paid when due shall accrue interest
         from the due date until paid, at a rate equal to the prime rate plus
         two percent (2%) with a maximum cap of eighteen percent (18%). CHCF may
         treat unpaid payments as a breach of this Agreement notwithstanding the
         payment of interest.

         3.7 RECORDS. Licensee will maintain complete and accurate books and
records which enable the royalties payable hereunder to be verified. The records
for each calendar quarter shall be maintained for five years after the
submission of each report under Section 3.5 hereof. Upon reasonable prior notice
to Licensee, CHCF and its accountant shall have access to the relevant books and
records of Licensee necessary to conduct a review or audit thereof. Such limited
access shall be available not more than twice each calendar year, during normal
business hours, and for three years after the expiration or termination of this
Agreement. If CHCF determines that Licensee has underpaid royalties by ten
percent (10%) or more, Licensee will immediately pay to CHCF such amount plus
interest as set forth in Section 3.6 above in addition to the documented costs
and expenses of CHCF's accountant in connection with its review or audit. If an
overpayment is determined to exist, CHCF shall refund any movies overpaid by
Licensee back to licensee.

                                   ARTICLE IV
                             USE OF LICENSED PROGRAM

         4.1 MAINTENANCE. Licensee acknowledges and agrees that CHCF shall be
under no obligation to Licensee to install, maintain, support, modify or enhance
the Licensed Work or any of it, all such obligations being the responsibility of
Licensee.

                                       7
<PAGE>

         4.2 COPY LIMITATIONS. Licensee shall be entitled to receive from CHCF
one copy of the each software program included in the Licensed Work (each a
"Licensed Program") and related documentation, and licensed technical
information. Licensee shall keep a record of the location of each and every copy
of each Licensed Program that it makes and shall maintain such copies in
locations consistent with Licensee's confidentiality obligations as set forth in
Article V hereof. Licensee shall reproduce without alteration any disclaimers,
legends and proprietary rights notices on all copies of each Licensed Program
and related documentation and licensed technical information.

         4.3 MODIFICATION OF LICENSED WORK.

         (a) Licensee shall have the right to make Modifications of the Licensed
         Work, including derivatives as contemplated by the copyright laws,
         provided that such Modifications, and all copyrights and trademarks
         relating thereto, shall remain the property of CHCF from the moment of
         their creation, subject to the Licensee's license rights hereunder.
         Licensee shall provide one copy of any Modification of the Licensed
         Work to CHCF promptly upon request. License shall obtain from each and
         every individual or entity who makes a Modification of the Licensed
         Work an assignment of all rights to CHCF, including but not limited to
         copyright, whether or not such contribution may be a "work made for
         hire." Prior to the commencement of work by such individuals or
         entities, Licensee shall have each individual or entity sign a document
         in reasonable form acknowledging that all rights in their respective
         contributions will be assigned to CHCF whether or not such
         contributions are works made for hire.

         (b) CHCF may from time to time release Modifications developed by CHCF,
         subject to the Licensee's license rights hereunder. CHCF will provide
         one copy of such Modifications to Licensee. The incorporation into the
         Licensed Work of any Modification developed by CHCF shall be reflected
         in the royalty schedule for the Licensed Work after good faith
         negotiations by the parties. Notwithstanding, licensee acknowledges and
         agrees that CHCF shall have no obligation to make Modifications of the
         Licensed Work.

         4.5 COMPLIANCE WITH LAWS. Licensee shall comply with all prevailing
laws, rules and regulations pertaining to the use of the Licensed Work, and
Licensee will be responsible for obtaining, at its cost and expense, any
governmental approvals required to use the Licensed Work. All rights granted to
Licensee by this Agreement are contingent upon compliance with United States
laws and regulations controlling the export of technical data, computer
software, laboratory prototypes, and all other export controlled commodities.
These laws include, but are not limited to, the Arms Export Control Act and the
Export Administration Act as they may be amended. Licensee shall not, directly
or indirectly, export any export controlled commodities, which are subject to
this Agreement, unless the required authorization and/or license is obtained
from the proper government agency(ies) prior to export. By granting rights in
this Agreement, CHCF does not represent that export authorization or an export
license will not be necessary or, if necessary, that such authorization or
export license will be granted.

                                       8
<PAGE>

                                    ARTICLE V
                                 CONFIDENTIALITY

         5.1 CONFIDENTIALITY.

         (a) NONDISCLOSURE. Licensee shall maintain in confidence and shall not
         disclose to any third party (except an authorized sublicensee) the
         Confidential Information received pursuant to this Agreement, without
         the prior written consent of CHCF. The foregoing obligation shall not
         apply to:

                  (i) information that is known to Licensee or independently
         developed by Licensee in the performance of services or work wholly
         unrelated to the Project prior to the time of disclosure, in each case,
         to the extent evidenced by written records promptly disclosed to CHCF
         upon receipt of the Confidential Information. This exception shall not
         apply to information learned by Licensee from any employee who was
         previously engaged by CHCF with responsibility for the development or
         use of the Licensed Work;

                  (ii) information disclosed to Licensee by a third party that
         has a right to make such disclosure;

                  (iii) information that becomes patented, published or
         otherwise part of the public domain as a result of acts by CHCF or by a
         third person who has the right to make such disclosure; or

                  (iv) information that is required to be disclosed by order of
         any governmental authority or a court of competent jurisdiction;
         provided that Licensee shall notify CHCF if it believes such disclosure
         is required and shall use its best efforts to obtain confidential
         treatment of such information by the agency or court.

         (b) USE OF CONFIDENTIAL INFORMATION. Licensee shall ensure that all of
         its employees having access to the Confidential Information of CHCF are
         obligated in writing to abide by Licensee's obligations hereunder.
         Licensee shall use the Confidential Information only for the purposes
         contemplated under this Agreement. Nothing in this Section 5.1 is
         intended to, or shall affect CHCF's rights to the CHCF Intellectual
         Property, or Licensee's payment obligations to CHCF hereunder.

         (c) NO OBLIGATION BY CHCF. CHCF shall not be obligated to accept any
         Confidential Information of the Licensee. If Licensee desires to
         furnish any of Licensee's Confidential Information to any CHCF
         personnel, Licensee may request such individual to sign a
         confidentiality agreement with Licensee in form and substance
         satisfactory to CHCF. CHCF bears no institutional responsibility for
         maintaining the confidentiality of any Confidential Information of
         Licensee.

                                       9
<PAGE>

         (d) COPYRIGHT NOTICE. The placement of a copyright notice by CHCF on
         the Licensed Work, or any portion thereof, shall not be construed to
         mean that the program or information has been published. Such placement
         will not release Licensee from its obligations of confidentiality
         hereunder.

         5.2 PUBLICATION. RIGHT TO PUBLISH. Neither CHCF nor Licensee shall
         disclose publicly, in writing or by oral presentation, Confidential
         Information related to the Licensed Work for which an appropriate form
         of intellectual property protection has not been filed without the
         prior written consent of the other party hereto.

         5.3                USE OF NAME.

         (a) Licensee shall not directly or indirectly use CHCF's name, or the
         name of any director, officer or employee thereof, without CHCF's
         written consent. CHCF hereby approves the use of the following wording
         as applied to CHCF, as appropriate:

                        (i)         [funded by]
                        (ii)        [licensed from]
                        (iii)       [developed in conjunction with]

         (b) CHCF and Licensee are independent entities and contractors and
         neither is an agent of the other. Neither Licensee nor CHCF shall take
         any action which would suggest to a reasonable person that an agency
         relationship exists between them.

         5.4 INJUNCTIVE RELIEF. Because damages at law will be an inadequate
remedy for breach of any of the covenants, promises and agreements contained in
this Article V hereof, CHCF shall be entitled to injunctive relief in any state
or federal court with jurisdiction, including specific performance or an order
enjoining the breaching party from any threatened or actual breach of such
covenants, promises or agreements. Licensee hereby waives any objection it may
have to the personal jurisdiction or venue of any such court with respect to any
such action. The rights set forth in this Section 5.4 shall be in addition to
any other rights which CHCF may have at law or in equity.

                                   ARTICLE VI
                         WARRANTIES AND REPRESENTATIONS

         6.1 REPRESENTATIONS AND WARRANTIES OF CHCF. CHCF represents and
warrants to Licensee that this Agreement, when executed and delivered by CHCF,
will be the legal, valid and binding obligation of CHCF, enforceable against
CHCF in accordance with its terms. CHCF also represents to Licensee that CHCF
has not received any written notice that the Licensed Work infringes the
proprietary rights of

                                       10
<PAGE>

any third party. These representations are to the knowledge of CHCF, based upon
conversations with certain CHCF officers. CHCF has made no independent
investigation of the matters which are subject to these representations.

         6.2 REPRESENTATION AND WARRANTIES OF LICENSEE. Licensee represents and
warrants to CHCF as follows:

         (a) Licensee is a good corporation duly organized, validity existing
         and in good standing under the laws of Pennsylvania, and has all
         requisite corporate power and authority to execute, deliver and perform
         this Agreement;

         (b) This Agreement, when executed and delivered by Licensee, will be
         the legal, valid and binding obligation of Licensee, enforceable
         against Licensee in accordance with its terms; and

         (c) The execution, delivery and performance of this Agreement by
         Licensee does not conflict with, or constitute a breach or default
         under, (i) the charter documents of Licensee, (ii) any law, order,
         judgment or governmental rule or regulation applicable to Licensee, or
         (iii) any provision of any agreement, contract, commitment or
         instrument to which Licensee is a party; and the execution, delivery
         and performance of this Agreement by Licensee does not require the
         consent, approval or authorization of, or notice or declaration to or
         filing or registration with, any governmental or regulatory authority.

                                   ARTICLE VII

                   LIMITATION ON LIABILITY AND INDEMNIFICATION

         7.1 NO WARRANTIES: LIMITATION ON LIABILITY. THE LICENSED WORK IS
PROVIDED ON AN "AS IS" BASIS AND CHCF MAKES NO REPRESENTATIONS OR WARRANTIES,
EXPRESS OR IMPLIED, WITH RESPECT TO THE LICENSED WORK. BY WAY OF EXAMPLE BUT NOT
OF LIMITATION, CHCF MAKES NO REPRESENTATIONS OR WARRANTIES (i) OF COMMERCIAL
UTILITY, (ii) OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE, OR (iii)
THAT THE USE OF THE LICENSED WORK WILL NOT INFRINGE ANY PATENT, COPYRIGHT OR
TRADEMARK OR OTHER PROPRIETARY OR PROPERTY RIGHTS OF OTHERS. EXCEPT AS EXPRESSLY
PROVIDED HEREIN, CHCF DISCLAIMS ANY WARRANTY THAT THE LICENSED WORK IS FREE FROM
THE RIGHTFUL CLAIMS OF ANY THIRD PARTY. CHCF SHALL NOT BE LIABLE TO LICENSEE,
LICENSEE'S SUCCESSORS OR ASSIGNS, OR ANY OTHER THIRD PARTY WITH RESPECT TO ANY
CLAIM ON ACCOUNT OF, OR ARISING FROM THE USE OF INFORMATION IN CONNECTION WITH
THE LICENSED WORK SUPPLIED HEREUNDER OR ANY OTHER MATERIAL OR ITEM DERIVED
THEREFROM. CHCF SHALL NOT BE LIABLE TO LICENSEE, OR ANY OTHER PERSON FOR ANY
LOSS OF PROFITS, LOSS OF BUSINESS OR INTERRUPTION OF BUSINESS, OR FOR ANY
INDIRECT, SPECIAL OR CONSEQUENTIAL DAMAGES OF ANY KIND INCURRED BY

                                       11
<PAGE>

LICENSEE OR ANY OTHER PERSON WHETHER UNDER THIS AGREEMENT OR OTHERWISE, EVEN IF
CHCF HAS BEEN ADVISED OF THE POSSIBILITY OF SUCH LOSS.

         7.2 LICENSEE INDEMNIFICATION. Licensee will indemnify and hold harmless
CHCF, its directors, officers, agents, representatives and employees
(collectively, the "Indemnified Parties"), from and against any and all
liability, loss, damage, action, claim or expense suffered or incurred by the
Indemnified Parties (including reasonable attorney's fees) (individually, a
"Liability" and collectively, the "Liabilities") which results from or arises
out of (a) the use of the Licensed Work by Licensee, its Affiliates, assignees,
vendors or other third parties; (b) breach by Licensee of any covenant or
agreement contained in this Agreement; and (c) the successful enforcement by an
Indemnified Party of its right under this Section 7.2. Without limiting the
foregoing, Licensee will indemnify and hold harmless the Indemnified Parties
from and against any Liabilities resulting from:

         (a) Any claim of any kind related to the use by a third party of the
         Licensed Work by Licensee, its Affiliates, assignees, or other third
         parties; and

         (b) A claim by a third party that the Licensed Work infringes or
         violates any patent, copyright, trademark or other intellectual
         property rights of such third party.

         7.3 PROCEDURES. The Indemnified Party shall promptly notify Licensee of
any claim or action giving rise to a Liability that is subject to the provisions
of Section 7.2. Licensee shall have the right to defend any such claim or
action, at its cost and expense. Licensee shall not settle or compromise any
such claim or action in a manner that imposes any restrictions or obligations on
CHCF or grants any rights to the Licensed Work, without CHCF's written consent,
which consent shall not be unreasonably withheld. If Licensee fails or declines
to assume the defense of any such claim or action within thirty (30) days after
notice thereof, CHCF may assume the defense of such claim or action for the
account and at the risk of Licensee, and any Liability related thereto shall be
conclusively deemed a liability of Licensee. Licensee shall pay promptly to the
Indemnified Party any Liabilities to which the foregoing indemnity relates, as
incurred. The indemnification rights of CHCF or other Indemnified Party
contained herein are in addition to all other rights which such Indemnified
Party may have at law or in equity or otherwise.

         7.4 LIABILITY INSURANCE. During the Term of this Agreement, Licensee
shall maintain general liability and product liability, insurance in amounts not
less than $1,000,000 per incident and $1,000,000 in the aggregate, issued by an
insurance company rated AA or better and naming CHCF as an additional insured.
The minimum insurance amounts specified herein shall not be deemed a limitation
on Licensee's indemnification liability under this Agreement. Licensee shall
provide CHCF with copies of the endorsements to such policies, upon request of
CHCF. Licensee shall notify CHCF at least thirty (30) days prior to cancellation
of any such coverage.

                                       12
<PAGE>

                                  ARTICLE VIII
                       PROPRIETARY RIGHTS AND INFRINGEMENT

         8.1         PROPRIETARY RIGHTS PROTECTION.

         (a) LICENSEE CONTROL. Licensee shall be responsible for and shall
         control the preparation, prosecution and maintenance of all copyrights
         and patent rights pertaining to the Licensed Work. Licensee shall be
         entitled to deduct from Fees all documented out-of-pocket expenses
         (including legal fees, filing and maintenance fees or other
         governmental charges) incurred in connection with the filing,
         prosecution and maintenance of any such rights ("Permitted Proprietary
         Rights Fees").

         (b) LICENSEE OBLIGATIONS. Licensee and CHCF shall mutually determine
         the countries where copyrights and patents pertaining to the Licensed
         Work will be prosecuted and maintained. If Licensee declines to pay for
         such prosecution and maintenance costs in any jurisdiction, CHCF may do
         so at its cost and expense but such rights shall be excluded from the
         definition of Licensed Work.

         (c) CHCF PROSECUTION. If Licensee elects not file, prosecute or
         maintain any copyright pertaining to the Licensed Work, it shall notify
         CHCF at least sixty (60) days prior to taking, or not taking, any
         action which would result in abandonment, withdrawal, or lapse of such
         right. CHCF shall then have the right to file, prosecute or maintain
         the right at its own expense and shall be reimbursed by Licensee (but
         only from Fees), with such reimbursed amounts (after such
         reimbursement) being deductible as Permitted Proprietary Rights Fees
         hereunder.

         (d) COOPERATION. Each party shall cooperate with the other party to
         execute all lawful papers and instruments and to make all rightful
         oaths and declarations as may be necessary in the preparation and
         prosecution of all rights referred to in this Section 8.1.

          8.2 OWNERSHIP. Licensee acknowledges that all right, title and
interest in and to the Licensed Work and any copyrights, patents, trademarks and
other protection related thereto is and shall remain in CHCF, regardless of
which party prepares prosecutes or maintains the foregoing, subject to the
express license granted to Licensee under Article II hereof. Licensee further
agrees to assign (or cause to be assigned) and does hereby assign fully to CHCF
all of Licensee's rights, if any, worldwide in the Licensed Work and all
intellectual property rights thereto including any copyrights, patents, patent
applications, trademarks, and tradenames, subject to the express license granted
to Licensee under Article II hereof.

         8.3       POWER TO SIGN.

                                       13
<PAGE>

         (a) CHCF agrees that if Licensee is unable because of CHCF's
         unavailability, incapacity, or for any other reason, to secure a
         signature by or on behalf of CHCF for or to pursue any application for
         any United States or foreign patents or copyright registrations
         covering the Licensed Work, then CHCF hereby irrevocably designates and
         appoints Licensee and its duly authorized officers and agents as CHCF's
         agent and attorney in fact, to act for and on CHCF's behalf and stead
         to execute, acknowledge, deliver and file any such applications and to
         do all other lawfully permitted acts to further the prosecution and
         issuance of patents and copyright registrations thereon with the same
         legal force and effect as if executed by CHCF.

         (b) Licensee agrees that if CHCF is unable because of Licensee's
         unavailability, incapacity, or for any other reason, to secure a
         signature by or on behalf of Licensee for or to pursue any application
         for any United States or foreign patents or copyright registrations
         covering the Licensed Work assigned to CHCF herein, then Licensee
         hereby irrevocably designates and appoints CHCF and its duly authorized
         officers and agents as Licensee's agent and attorney in fact, to act
         for and on Licensee's behalf and stead to execute, acknowledge, deliver
         and file any such applications and to do all other lawfully permitted
         acts to further the prosecution and issuance of patents and copyright
         registrations thereon with the same legal force and effect as if
         executed by Licensee.

         8.4       INFRINGEMENT BY THIRD PARTY.

         (a) LICENSEE'S OBLIGATIONS. Each party will promptly notify the other
         party of any infringement or possible infringement of rights relating
         to the Licensed Work. Licensee shall have the right, but not the
         obligation, to prosecute such infringement at its own expense. In such
         event, CHCF shall cooperate with Licensee, at Licensee's expense.
         Licensee shall not settle or compromise any such suit in a manner that
         imposes any obligations or restrictions on CHCF or grants any rights to
         the Licensed Work, without CHCF's written consent.

         (b) CHCF'S RIGHTS. If Licensee fails to prosecute such infringement
         within ninety (90) days after receiving notice thereof, CHCF shall have
         the right, but not the obligation, to prosecute such infringement at
         its own expense. In such event, Licensee shall cooperate with CHCF, at
         CHCF's expense.

         (c) RECOVERY DISTRIBUTION. Any recovery obtained by the prosecuting
         party as a result of such proceeding, by settlement or otherwise, shall
         be applied first to the prosecuting party, in an amount equal to its
         costs and expenses of the litigation, with the remainder to be paid to
         Licensee, subject to the earned royalties due to CHCF under Article 3
         hereof.

                                   ARTICLE IX
                              TERM AND TERMINATION

                                       14
<PAGE>

         9.1 TERM. This Agreement and the licenses granted herein shall commence
on the Effective Date and shall continue, subject to earlier termination under
Sections 9.2 or 9.3 hereof, for a period of thirty (30) years thereafter.

         9.2      TERMINATION BY CHCF.

         (a) EVENTS OF DEFAULT. Upon the occurrence of any of the events set
         forth below ("Events of Default"), CHCF shall have the right to
         terminate this Agreement by giving written notice of termination, such
         termination being effective with the giving of such notice:

                  (i) nonpayment of any amount payable to CHCF that is
         continuing ten (10) calendar days after CHCF gives Licensee written
         notice of such nonpayment;

                  (ii) breach by Licensee of any covenant (other than a payment
         breach referred to in clause (i) above) or any representation or
         warranty contained in this Agreement that is continuing sixty (60)
         calendar days after CHCF gives Licensee written notice of such breach;
         provided that if Licensee, using its best efforts, cannot cure such
         breach within the first sixty (60) days, the cure period shall be
         extended by an additional sixty (60) calendar days, the total cure
         period not to exceed one hundred twenty (120) days;

                  (iii) Licensee fails to comply with the terms of the license
         granted under Article II hereof and such noncompliance is continuing
         thirty (30) calendar days after CHCF gives Licensee notice of such
         noncompliance;

                  (iv) Licensee becomes subject to a Bankruptcy Event;

                  (v) the dissolution or cessation of operations by Licensee; or

                  (vi) Licensee has failed to receive any fees for use or
         sublicensing of the Licensed Program by December 31, 2001.

         (b) NO WAIVER. No exercise by CHCF of any right of termination shall
         constitute a waiver of any right of CHCF for recovery of any monies
         then due to it hereunder or any other right or remedy CHCF may have at
         law or under this Agreement.

         (c) SUBLICENSES. Any sublicense(s) in effect at the time of such
         termination by CHCF will be assigned to CHCF and will remain in full
         force and effect so long as (1) Licensee is in full compliance with the
         terms and conditions of any such sublicense(s), and (2) such
         sublicense(s) are consistent with the terms of this Agreement, and (3)
         CHCF has no obligation to provide any support, maintenance or other
         service to sublicensee. The assignment will occur

                                       15
<PAGE>

         automatically upon the request of Licensee, notwithstanding the
         provision of 9.5 "Sublicenses".

         9.3 TERMINATION BY LICENSEE. Licensee shall have the right to terminate
this Agreement, after the last day of the stated term of the Consulting
Agreement with or without cause, upon (90) days written notice to CHCF at which
point, subject to Section 9.5, all rights to the Licensed Work shall revert to
CHCF. No such termination shall constitute a waiver of any right of CHCF for
recovery of any monies then due to it hereunder or any other right or remedy
CHCF may have at law or under this Agreement.

          9.4 RIGHTS AND DUTIES UPON TERMINATION. Within thirty (30) days after
termination of this Agreement, each party shall return to the other party any
Confidential Information of the other party. Licensee also shall return all
copies of Licensed Programs or other portions of the Licensed Work in its
possession that are embodied in physical form to CHCF promptly upon the
termination of this Agreement.

          9.5 SUBLICENSES. Any sublicenses granted by Licensee under this
Agreement may survive termination of this Agreement in accordance with the terms
of such sublicense if so requested by CHCF, in which event the sublicense shall
be assigned to CHCF.

          9.6 PROVISIONS SURVIVING TERMINATION. Licensee's obligation to pay
Royalties accrued but unpaid prior to termination of this Agreement shall
survive such termination. In addition, Sections 3.8, 3.9, 4.1, 8.2, 8.3 and this
9.6 and Articles V, VI and VII and any other provisions required to interpret
the rights and obligations of the parties arising prior to the termination date
shall survive expiration or termination of this Agreement.

                                    ARTICLE X
                              ADDITIONAL PROVISIONS

          10.1 SAFETY NET PROVIDERS. During the term of this Agreement, Licensee
shall provide the products and services relating to or derived from the Project
to Safety Net Providers at a price that is at least 25% less than the most
favorable then-current price offered for the same or similar products or
services, as the case may be, to similarly situated providers.

          10.2 ANCHOR AGREEMENTS. Licensee shall enter into an agreement with
each Care Alliance Anchor in substantially the form set forth in Exhibit A
attached hereto. CHCF shall, in its sole discretion, have the right to approve
or disapprove of any schedule to such agreement or schedule to any exhibit of
such agreement prior to its effectiveness.

          10.3 ASSIGNMENT. This Agreement and the rights and duties appertaining
thereto may not be assigned by the Licensee, directly or indirectly except to an
Affiliate of Licensee wherein Licensee guarantees performance of assignee or in
the case of

                                       16
<PAGE>

merger, acquisition or operation of law, without first obtaining the
written consent of CHCF. Any such purported assignment, without the written
consent of CHCF, shall be null and of no effect. No assignment shall relieve
Licensee of responsibility for the performance of any obligations which have
accrued prior to such assignment.

          10.4 NO WAIVER. A waiver by either party of a breach or violation of
any provision of this Agreement must be in writing in order to be effective. No
waiver will constitute or be construed as a waiver of any subsequent breach or
violation of that provision or as a waives of any breach or violation of any
other provision of this Agreement.

          10.5 INDEPENDENT CONTRACTOR. Nothing herein shall be deemed to
establish a relationship of principal and agent between CHCF and Licensee, nor
any of their agents or employees for any purpose whatsoever. This Agreement
shall not be construed as constituting CHCF and Licensee as partners, or as
creating any other form of legal association or arrangement which could impose
liability upon one party for the act or failure to act of the other party.

          10.6 NOTICES. Any notice under this Agreement shall be sufficiently
given if sent in writing by prepaid, first class, certified or registered mail,
return receipt requested, addressed as follows:

         (a)       if to CHCF, to:

                           California Healthcare Foundation
                           476 Ninth Street
                           Oakland, CA  94607
                           Attn:  Sam Karp, Chief Information Officer
                           Phone:  (510) 238-1040
                           Facsimile:  (510) 238-1388

         (b)      if to Licensee, to:

                           CareScience, Inc.
                           3600 Market Street, 6th Floor
                           Philadelphia, PA 19104
                           Attn:  Ronald A. Paulus, President
                           Phone:  (215) 387-9401
                           Facsimile:  (215) 387-9406

or to such other addresses as may be designated from time to time by notice
given in accordance with the terms of this Section.

          10.7 ENTIRE AGREEMENT; EFFECT ON EXISTING AGREEMENT. This Agreement
embodies the entire understanding between the parties relating to the subject
matter hereof and supersedes all prior understandings and agreements, whether
written or oral,

                                       17
<PAGE>

including without limitation Section 9 of the Consulting Agreement. The parties
acknowledge and agree that Section 9 of the Consulting Agreement is hereby
replaced in its entirety by this Agreement, which shall be deemed to apply to
all matters covered hereby since the effective date of the Consulting Agreement,
October 1, 1999, it being the intent of the parties that all such matters shall
be governed by this Agreement, rather than some by the provisions of Section 9
of the Consulting Agreement and others by this Agreement. This Agreement may not
be varied except by a written document signed by duly authorized representatives
of both parties.

          10.8 SEVERABILITY. Any of the provisions of this Agreement which are
determined to be invalid or unenforceable in any jurisdiction shall be
ineffective to the extent of such invalidity or unenforceability in such
jurisdiction, without rendering invalid or unenforceable the remaining
provisions hereof or affecting the validity or unenforceability of any of the
terms of this Agreement in any other jurisdiction.

          10.9 HEADINGS. Any headings and captions used in this Agreement are
for convenience of reference only and shall not affect its construction or
interpretation.

          10.10 NO THIRD PARTY BENEFITS. Nothing in this Agreement, express or
implied, is intended to confer on any person other than the parties hereto or
their permitted assigns, any benefits, rights or remedies.

          10.11 GOVERNING LAW. This Agreement shall be construed, governed,
interpreted and applied in accordance with the laws of the State of California,
without giving effect to conflict of law provisions.

          10.12 COUNTERPARTS. This Agreement shall become binding when any one
or more counterparts hereof, individually or taken together, shall bear the
signatures of each of the parties hereto. This Agreement may be executed in any
number of counterparts, each of which shall be deemed an original as against the
party whose signature appears thereon, but all of which taken together shall
constitute but one and the same instrument.

                                       18
<PAGE>

INTENDING TO BE BOUND, the parties hereto execute this Agreement through their
authorized representatives as of the date first written above.

                       CALIFORNIA HEALTHCARE FOUNDATION

                      By:/s/ CRAIG C. ZIEGLER
                      -----------------------
                      Name:  Craig C. Ziegler
                      Title:  Chief Financial Officer

                      CARESCIENCE, INC.

                      By:/s/ RONALD A. PAULUS
                      -----------------------
                      Name:  Ronald A. Paulus
                      Title: President

                                       19
<PAGE>

                                    EXHIBIT A

                  FORM OF AMENDED AND RESTATED ANCHOR AGREEMENT

                                       A-1
<PAGE>

                                CARESCIENCE, INC.
                      AMENDED AND RESTATED ANCHOR AGREEMENT

         THIS AMENDED AND RESTATED ANCHOR AGREEMENT ("Agreement") is entered
this _____ day of INSERT MONTH AND YEAR into by and between INSERT ANCHOR NAME
("Anchor"), a INSERT STATE AND TYPE OF ORGANIZATION located at INSERT ADDRESS,
and CareScience, Inc. ("CS"), a Pennsylvania corporation with offices at 3600
Market Street, 6th Floor, Philadelphia, PA 19104.

         WHEREAS, the parties desire to participate in the evaluation of the
efficacy of community-wide data sharing within the County of Santa Barbara,
California (the "Project"), sponsored by the California Healthcare Foundation,
("CHCF") a California non-profit public benefit corporation located at 476 Ninth
Street, Oakland, CA 94607, which project will be managed by CS;

         WHEREAS, the parties intend that any data to be shared by them in
connection with the Project which is "protected health information" as defined
in proposed 45 C.F.R. Part 164 or any such succeeding final regulations (the
"HHS Regulations") shall be used only for treatment, payment or health care
operations, as defined in the HHS Regulations, unless prior written consent is
obtained from the individual subjects of such data or such data is de-identified
in compliance with the HHS Regulations;

         WHEREAS, the parties both recognize that the Project is contingent upon
receipt of funds from CHCF;

         WHEREAS, the parties are party to an Anchor Agreement, dated as of
________ (the "Original Anchor Agreement");

         WHEREAS, the parties desire to amend and restate the Original Anchor
Agreement in its entirety as set forth herein;

         NOW, THEREFORE, in consideration of the mutual promises and covenants
contained herein, and intending to be legally bound hereby, the parties hereto
agree as follows:

1.       CERTAIN DEFINITIONS:

         1.1      "ANCHOR" has the meaning set forth in the preamble.
         1.2      "CARE DATA EXCHANGE PROJECT IP" means any and all IP used in,
                  developed during, or related to the data exchange project
                  funded by CHCF (the "Data Exchange Project"), which is a
                  project to develop (i) concepts related to, (ii) a methodology
                  for, and (iii) means of effecting the electronic distribution
                  and sharing or exchange of data through a site or sites
                  located on the world wide web, which data may consist of text,
                  graphics, still or moving images, audio files, e-mail or other
                  content.
         1.3      "CHCF" has the meaning set forth in the preamble.
         1.4      "CHCF INTELLECTUAL PROPERTY" means any and all IP which is
                  either Care Data Exchange Project IP or Vendor Certification
                  Project IP and not (i) data which solely identifies a specific
                  individual or entity, (ii) a standard software product (i.e.,
                  a product generally available for license to consumers (e.g.,
                  "Windows" or "Quicken" products)) licensed or purchased in the
                  ordinary course of business or (iii) a software product set
                  forth on Schedule 1.4 and which is solely an internal system
                  or process of an Anchor or member of a Care Alliance team
                  (i.e. not necessary to the functioning of any work included in
                  the Care Data Exchange Project IP or the Vendor Certification
                  Project IP).
         1.5      "COMMITTEE" has the meaning set forth in Section 9.1.
         1.6      "CS" has the meaning set forth in the preamble.
         1.7      "DELIVERABLES" means those items that the Anchor is
                  responsible for delivering or ensuring the delivery of in
                  order to comply with the terms and conditions of this
                  Agreement as set forth in Exhibit 1.7 or as otherwise required
                  to receive payment from CHCF.

                                 A-2
<PAGE>

         1.8      "EFFECTIVE DATE" means INSERT DATE, the date upon which the
                  services under this Agreement began in support of the Project;
         1.9      "IP" means any and all business models, copyrights, data,
                  software, technical and other documentation, trade secret
                  rights (including any that may be included in any patent
                  applications), and all other intellectual property rights as
                  may now exist or hereafter come into existence and be
                  protectable by law anywhere throughout the world, and all
                  applications and registrations therefor, patent rights, and
                  name, brand, mark trademark, service mark, trade dress,
                  business name or other indicia of origin including without
                  limitation any registrations, applications and renewals
                  therefor.
         1.10     "ORIGINAL ANCHOR AGREEMENT" has the meaning set forth in the
                  preamble.
         1.11     "PARTICIPANTS" means those organizations listed on Exhibit 1.7
                  (as may be amended from time to time by written agreement of
                  the parties) with whom Anchor has entered into a Care Data
                  Alliance Agreement described in Section 6.1.
         1.12     "PLANNING DOCUMENT" is defined under the Deliverables in
                  Exhibit 1.7.
         1.13     "PROJECT" has the meaning set forth in the preamble.
         1.14     "PROJECT COMPENSATION" is defined under Compensation in
                  Section 7.1.
         1.15     "VENDOR CERTIFICATION PROJECT IP" means any and all IP used
                  in, developed during, or related to the vendor certification
                  project funded by CHCF, which is a project to develop (i)
                  concepts related to, (ii) a methodology for, and (iii) means
                  of effecting the electronically-enabled application for
                  certification of vendors or suppliers of goods or services to
                  be used in connection with the Data Exchange Project or any
                  similar data exchange project ("Project Vendors"),
                  certification of Project Vendors, promulgation of Project
                  Vendor standards, distribution of tools and/or information
                  about tool sets required for Project Vendor certification, and
                  to display Project Vendors' certification status and results.
         1.16     All other capitalized terms used, but not defined herein have
                  the meaning ascribed to such terms in the Santa Barbara County
                  Data Exchange Accord.

2.       TERM OF ENGAGEMENT.

         2.1      CS hereby engages Anchor on the terms and conditions as
                  defined herein to take on the responsibilities as specified
                  for Anchor in this Agreement and to develop or to ensure the
                  development of the Deliverables in accordance with the
                  description and timeline as set forth in Exhibit 1.7 attached
                  hereto.
         2.2      The term of this Agreement ("Term") shall be for a period from
                  the Effective Date through INSERT TERMINATION DATE and shall
                  automatically terminate on INSERT TERMINATION DATE or upon the
                  completion of the scope of work as stated in Exhibit 1.7,
                  whichever comes first, unless otherwise terminated earlier as
                  allowed herein.

3.       PROVISION OF SERVICES. Anchor may, at Anchor's discretion and at
         Anchor's own expense, use consultants or other third parties to perform
         the services required to generate the Deliverables required under this
         Agreement so long as Anchor guarantees the performance of any such
         consultants or third parties and provides written notice to CS of its
         intent to use such any such consultants or third parties.

4.       TERMINATION.

         4.1      MUTUAL TERMINATION RIGHTS.

                  4.1.1    BREACH. Either party may terminate this Agreement
                           upon the provision of at least four (4) weeks advance
                           written notice to the other party in the event that
                           the other party is in breach of a material provision
                           of this Agreement and fails to cure that breach to
                           the reasonable satisfaction of the other party within
                           four (4) weeks of receipt of notice (or such longer
                           time that may be specified in the notice).
                  4.1.2    CESSATION OF OPERATIONS OR BANKRUPTCY. In the event
                           either party ceases its business operations or files
                           for or declares bankruptcy or is otherwise deemed
                           insolvent, then the other party may, subject to the
                           restrictions imposed by federal bankruptcy law, at
                           its sole

                                       A-3
<PAGE>

                           discretion, terminate this Agreement upon
                           giving written notice of termination to the other
                           party.
                  4.1.3    Either party may terminate this Agreement upon the
                           provision of at least four (4) weeks advance written
                           notice to the other party.

         4.2      CS RIGHT OF TERMINATION.

                  4.2.1    ANCHOR'S INABILITY TO PRODUCE DELIVERABLES. If in
                           CS' reasonable judgment, it determines that Anchor
                           will be unable to produce the Deliverables required
                           under this Agreement according to the schedule set
                           forth in Exhibit 1.5, CS reserves the right to
                           terminate this Agreement upon four (4) weeks' written
                           notice to Anchor unless Anchor is able to demonstrate
                           to CS' reasonable satisfaction that it will be able
                           to produce the Deliverables and that demonstration
                           occurs within four (4) weeks of receipt of CS' notice
                           of termination.

                  4.2.2    FAILURE TO PRODUCE DELIVERABLES IN A PROFESSIONAL
                           MANNER. Anchor's failure to perform the services
                           required to produce the Deliverables in a
                           professional manner, as determined by CS in its sole
                           discretion, shall constitute a material breach of
                           this Agreement. CS reserves the right to terminate
                           this Agreement if Anchor repeatedly fails to produce
                           the Deliverables in a professional manner upon four
                           (4) weeks' written notice to Anchor, unless Anchor is
                           able to demonstrate to CS' satisfaction that it will
                           be able to produce the Deliverables in a professional
                           manner and that demonstration occurs within four (4)
                           weeks of receipt of CS' notice of termination. Anchor
                           shall be solely responsible for the professional
                           performance of the services required to produce the
                           Deliverables, and shall receive no assistance from,
                           and will not be under the control of, CS.

                  4.2.3    CHCF'S TERMINATION OF THIS PROJECT. CS may terminate
                           this Agreement upon the provision of two (2) days
                           advance written notice in the event that CHCF
                           terminates its project contract with CS.

         4.3      LIMITATION ON POST-TERMINATION PAYMENT OBLIGATIONS. In the
                  event that CS terminates this Agreement under the provisions
                  of Sections 4.1.1, 4.1.3, 4.2.1, or 4.2.2, (A) neither CS nor
                  CHCF shall have any further payment obligation to Anchor
                  except for any Project Compensation (as defined below)
                  contingent upon Deliverables already made and accepted by CS
                  but not yet paid to Anchor and (B) Anchor shall immediately
                  refund to CHCF any payments advanced to it for Deliverables
                  not yet made or accepted by CS. In the event that CS
                  terminates this Agreement under the provisions of Sections
                  4.1.2 or 4.2.3 or Anchor terminates this Agreement under
                  Section 4.1.1, Anchor shall be reimbursed for all reasonable
                  expenses that would otherwise be allowed under this Agreement
                  that have been incurred by but not yet reimbursed to Anchor.
                  If Anchor has any funds in excess of these expenses they shall
                  be immediately refunded to CHCF. In the event that Anchor
                  terminates this Agreement under the provisions of Section
                  4.1.3, Anchor shall immediately inform CS of its termination
                  in writing, shall refund funding for any incomplete
                  deliverables on a pro-rated basis directly and immediately to
                  CHCF and shall deliver all CHCF Intellectual Property in
                  Anchor's possession directly and immediately to CHCF.

5.       CARE DATA EXCHANGE.

         5.1      Anchor has signed the Santa Barbara County Care Data Exchange
                  Accord, a copy of which is attached hereto as Exhibit 5.1, and
                  will remain an active Member of the Care Data Exchange at all
                  times during the Term of this Agreement. Anchor will use its
                  best efforts to develop and support the growth and expansion
                  of the Care Data Exchange, participate on the Care Data
                  Exchange Council and attend all Care Data Exchange meetings.

         5.2      Anchor will allow external parties to engage in discussions
                  with and visit Anchor's premises and use reasonable efforts to
                  allow such parties to engage in discussions with and visit
                  Participants' premises from time to time upon request and
                  reasonable notice from CS in furtherance of understanding
                  and/or assessing the success of the Project, and will
                  cooperate with such parties' reasonable requests to meet with
                  Anchor's representatives and/or Participants' representatives.

                                      A-4

<PAGE>

         5.3      Anchor will participate in all Care Data Exchange Conferences
                  and Vendor Exhibitions held in or within __[INSERT A NUMBER]
                  miles of Santa Barbara County.

6.       CARE DATA ALLIANCE AGREEMENTS.

         6.1      As part of its Deliverables, Anchor will enter into a Care
                  Data Alliance Agreement, in the form attached as Exhibit 6.1,
                  with the Participants. Anchor may not enter into, amend,
                  terminate or waive any rights under a Care Data Alliance
                  Agreement without CS' advance written approval unless this
                  Agreement has been terminated.

         6.2      Anchor will lead and participate in the Care Data Alliance and
                  ensure that Participants participate in the Care Data
                  Alliance.

         6.3      Anchor will make payments to Participants according to the
                  Payment Schedule set forth in Exhibit 7 and in accordance with
                  the Care Data Alliance Agreement.

         6.4      Neither the Anchor nor the Participant may use funds provided
                  under this agreement to purchase, lease or otherwise contract
                  for technology that is not certified by CS. Anchor
                  acknowledges and agrees that although CS has the right to
                  certify any purchase or use of technology, CS is not
                  guaranteeing that such technology will work or be compatible
                  with the Project.

7.       COMPENSATION.

         7.1      COMPENSATION. Compensation will be paid to Anchor by CHCF in
                  accordance with the payment schedule set forth in Exhibit 7
                  and in accordance with the approvals and instructions provided
                  by CS as set forth in its agreement with CHCF dated October 1,
                  1999. Anchor hereby acknowledges and agrees that CHCF may not
                  modify the Deliverables or the Payment Schedule without the
                  advance written approval of CS. Anchor further acknowledges
                  and agrees that CHCF (and not CS) is providing the payments
                  set forth in Exhibit 7 (the "Project Compensation") and that
                  CS shall have no liability to Anchor or any other person if
                  CHCF fails to pay any Project Compensation due to Anchor.

         7.2      FUNDS ARE TO BE USED ONLY FOR DELIVERABLES. The Project
                  Compensation funds may not be used for any purposes other than
                  those specifically required to meet the Deliverables and that
                  are consistent with the purpose of the project. Anchor is
                  responsible for all expenses other than those specifically
                  provided for in this Agreement.

         7.3      AUDITS. Anchor shall maintain full and complete records (which
                  shall be made available to CS and/or CHCF and their respective
                  agents) to the extent reasonably required by CS and/or CHCF to
                  permit CS and/or CHCF (or their respective agents) to audit
                  invoices related to project expenditures. CS or CHCF (or their
                  respective agents), at its own expense, will periodically
                  audit a selected number of its contracts. If Anchor is
                  selected for an audit, Anchor shall provide all reasonable
                  assistance in connection with such audit. Anchor acknowledges
                  and agrees that CS may provide to CHCF copies of any and all
                  information provided to CS by Anchor related to the Project or
                  this Agreement. Records must be kept for at least three (3)
                  years after completion of this Agreement.

         7.4      NO OTHER OBLIGATIONS OF CHCF. CHCF shall have no obligation or
                  liability to Anchor for any performance or non-performance
                  under this Agreement by CS, or for any payments, liabilities
                  or obligations of Anchor or CS other than the Project
                  Compensation payable in accordance with the other terms and
                  conditions hereof.

8.       INDEPENDENT CONTRACTOR.

         8.1      Anchor enters into this Agreement as, and shall continue to
                  be, an independent contractor. Under no circumstances shall
                  Anchor look to CS or CHCF as its employer, or as a partner,
                  agent or principal. Anchor shall not be entitled to any
                  benefits which may be accorded to CS's or CHCF's employees,
                  including workers' compensation, employee benefit plans,
                  disability insurance, vacation or sick pay. Anchor shall be
                  responsible for providing, at Anchor 's expense, and in
                  Anchor's name, disability, workers' compensation or other
                  insurance as well as licenses and permits usual or necessary
                  for performing the Services.

                                      A-5

<PAGE>

         8.2      Anchor shall be responsible for all wages, withholding,
                  workers compensation and all other fringe benefits for its
                  employees. Anchor is not an agent of CS or CHCF, nor shall
                  Anchor possess any right or authority to bind CS or CHCF in
                  any manner without the consent of CS or CHCF as the case may
                  be. None of Anchor's employees shall hold themselves out to
                  third parties to be, or otherwise represent in any manner that
                  they are, an officer, director, agent or employee of CS or
                  CHCF or their affiliates, or that such employee of Anchor has
                  authority to bind CS or CHCF or any of their affiliates.

         8.3      Anchor shall pay, when and as due, any and all taxes incurred
                  as a result of the compensation paid to Anchor hereunder,
                  including any estimated taxes, and shall provide CS with proof
                  of payment on demand.

         8.4      Anchor hereby represents and warrants to CS that it has
                  verified the immigration status of each of its employees as
                  required by applicable law and regulations, and is in
                  compliance with all applicable federal immigration law and
                  regulations with respect to each of its employees.

9.       INTELLECTUAL PROPERTY.

         9.1      Anchor acknowledges and agrees, for good and valuable
                  consideration, including, without limitation, that specified
                  in Section 7 hereof, that all CHCF Intellectual Property and
                  all intellectual property rights therein and appurtenant
                  thereto, including, without limitation, all intellectual
                  property arising in or developed as a result of Anchor's
                  participation in the Committee, are and will remain the sole
                  and exclusive property of CHCF except as otherwise determined
                  in writing by CHCF. Anchor further agrees to assign (or cause
                  to be assigned) and does hereby assign fully to CHCF all of
                  Anchor's worldwide rights, title and interest, if any,
                  worldwide in such CHCF Intellectual Property and all
                  intellectual property rights therein and appurtenant thereto,
                  including, without limitation, any copyrights, patents, patent
                  applications, trademarks, and trade names. CHCF shall have the
                  right to obtain and hold in its own name patents, copyright
                  registrations, or other such protection as may be appropriate
                  to the subject matter, and any extensions and renewals
                  thereof. Anchor agrees to give CHCF and any person designated
                  by CHCF such reasonable assurance and assistance (at CHCF's
                  expense for all out-of-pocket costs incurred in connection
                  therewith) as is required to obtain patents, copyright
                  registrations or otherwise to perfect CHCF's rights in any
                  CHCF Intellectual Property. As used herein "Committee" shall
                  mean any committee or group constituted to consider the
                  Project, or any aspect thereof.

         9.2      Anchor acknowledges and agrees that CHCF will at all times
                  have the right, in its sole and exclusive discretion, to sell,
                  license, or otherwise exploit in any medium now or hereafter
                  known, any of the CHCF Intellectual Property.

         9.3      Anchor agrees that if CHCF is unable because of Anchor's
                  unavailability, incapacity, or for any other reason, to secure
                  a signature by or on behalf of Anchor or to pursue any
                  application for any United States or foreign patents or
                  copyright registrations covering the CHCF Intellectual
                  Property assigned to CHCF herein, then Anchor hereby
                  irrevocably designates and appoints CHCF and its duly
                  authorized officers and agents as Anchor's agent and attorney
                  in fact, to act for and on Anchor's behalf and stead to
                  execute, acknowledge, deliver and file any such applications
                  and to do all other lawfully permitted acts to further the
                  prosecution and issuance of patents and copyright
                  registrations thereon with the same legal force and effect as
                  if executed by Anchor.

         9.4      Anchor agrees that Anchor will not have or be deemed to have
                  any lien, charge or other encumbrance upon any of the rights
                  conveyed to CHCF herein, the CHCF Intellectual Property, or
                  any proceeds derived therefrom, and that no act or omission by
                  CHCF or CS, nor any other act, omission or event of any kind,
                  will terminate or otherwise adversely affect CHCF's ownership
                  of the rights conveyed herein.

         9.5      Anchor agrees to secure a right on behalf of CHCF identical to
                  this right in any agreements with any Participants.

10.      MUTUAL CONFIDENTIALITY.

                                      A-6
<PAGE>

         10.1     Both parties acknowledge that during the course of this
                  Agreement, either party may have access to information which
                  is confidential to, or a trade secret of, the other party or
                  CHCF. Both parties agree not to disclose any such information,
                  regardless of the form or format in which, or means by which,
                  the other party becomes aware of such information, to any
                  third party without the specific written authorization of the
                  other party or CHCF as the case may be. For the purposes of
                  this Agreement, trade secrets and confidential information
                  shall not include information that (i) is generally available
                  to the public (other than as a result of a disclosure by a
                  party hereto or its affiliates), or (ii) is available to such
                  party on a non-confidential basis from a source that is not
                  prohibited from disclosing such information to such party.

         10.2     All CHCF Intellectual Property shall be deemed trade secret
                  and/or confidential information of CHCF, and Anchor shall not,
                  and shall have no right to disclose or authorize the
                  disclosure of such information to any person or entity without
                  the prior written consent of CHCF. Notwithstanding the
                  foregoing, officers of Anchor shall be allowed to speak
                  publicly about the processes and materials developed in the
                  course of Anchor's performance of this Agreement so long no
                  CHCF Intellectual Property is disclosed without CHCF's
                  consent.

         10.3     Both parties agree to take whatever measures are reasonably
                  necessary, by notice, agreement or otherwise, to ensure that
                  any employee of either party, or anyone provided access
                  thereto by either party shall be personally bound to maintain
                  the confidentiality of any and all information acquired in the
                  course of providing services under this Agreement.

11.      INDEMNIFICATION.

         11.1     Anchor hereby agrees to indemnify, defend and hold harmless CS
                  and CHCF, and CS's and CHCF's officers and directors from and
                  against any and all claims, demands, losses, costs, expenses,
                  obligations, liabilities, damages, recoveries, and
                  deficiencies, including interest and penalties, and reasonable
                  attorneys' fees and costs, that CS or CHCF may incur or suffer
                  and that result from, or are related to, (i) any breach or
                  failure of Anchor to perform any representations, warranties,
                  covenants or other agreements contained in this Agreement,
                  including, but not limited to, Anchor's failure to produce the
                  Deliverables in accordance with the schedule set forth on
                  Exhibit 1.5, (ii) any assertion, claim or cause of action by
                  any employee or consultant of Anchor that such consultant or
                  employee is entitled to any benefits form CS or CHCF, or (iii)
                  Anchor's breach of the Care Data Alliance Agreement.

         11.2     Each party shall indemnify and hold the other party harmless
                  from and against any and all claims, liabilities, injuries,
                  suits, demands and expenses of all kinds (including reasonable
                  attorney's fees) that may result or arise out of the other
                  party's negligent, reckless, deliberate, illegal or fraudulent
                  acts or omissions. In the event that a claim is made against
                  both parties, it is the intent of both parties to reasonably
                  cooperate in the defense of said claim.

12.      REPRESENTATIONS OF ANCHOR. Anchor represents and warrants that Anchor
         has the qualifications and ability to perform the services required to
         produce the Deliverables in a professional manner, without the advice,
         control, or supervision of CS. Anchor further represents and warrants
         that Anchor possesses any and all licenses and governmental approvals
         required in order for Anchor to perform the services required to
         produce the Deliverables. Anchor's execution of this Agreement and its
         performance of the services contemplated herein do not and will not
         contravene any laws, regulations or rules of any state, federal, or
         non-governmental regulatory body. No consent of any third party is
         required for the execution by Anchor of this Agreement and the
         performance of the services contemplated herein. Anchor's
         representations and warranties in this Agreement shall survive
         termination of this Agreement.

13.      GENERAL PROVISIONS.

         13.1     BINDING ON SUCCESSORS. Subject to any restrictions stated in
                  any other provision of this Agreement, this Agreement shall be
                  binding on and shall inure to the benefit of the parties and
                  their respective successors and permitted assigns. Except for
                  CHCF, none of the provisions of this

                                      A-7

<PAGE>

                  Agreement is intended to provide any rights or remedies to any
                  person (including without limitation any employees or
                  creditors of either of the parties hereto), other than the
                  parties and their respective successors and permitted assigns.
                  Notwithstanding the rights and remedies expressly conferred on
                  CHCF herein, CHCF is not a party to this Agreement, and shall
                  have no obligations to Anchor or CS, or be responsible in any
                  way for the performance or non-performance of Anchor or CS
                  hereunder, provided that CHCF shall make the Project
                  Compensation payments to Anchor subject to the other terms and
                  conditions hereof.

         13.2     PARTIAL INVALIDITY/SEVERABILITY. Should any of the provisions
                  of this Agreement be held to be invalid or unenforceable, such
                  invalidity or unenforceability shall not affect the validity
                  or enforceability of any other provision of this Agreement.

         13.3     ENTIRE AGREEMENT. This Agreement contains the entire agreement
                  between the parties with respect to the subject matter of this
                  Agreement and supersedes all prior oral or written
                  understandings and agreements including, but not limited to,
                  any and all consulting or consultancy agreements, promissory
                  notes, summary of agreements, discharge agreements,
                  non-disclosure agreements, reduction of debts agreements, and
                  any other document executed between the parties or their
                  agents, employees, officers or shareholders.

         13.4     AMENDMENTS; WAIVERS. No provision of this Agreement may be
                  changed, extended, waived, modified, discharged or terminated,
                  except by a written instrument executed by the parties hereto,
                  provided that no such amendment, modification, discharge or
                  termination shall be effective unless and until CHCF agrees
                  thereto in writing.

         13.5     NOTICE. Any notice, payment, report or any other communication
                  required or permitted to be given by one party to the other
                  party by this Agreement shall be in writing, shall be deemed
                  effective upon receipt and shall be either (a) served
                  personally on the other party, (b) sent by express, registered
                  or certified first-class mail, postage prepaid, addressed to
                  the other party by like notice, or (c) delivered by commercial
                  courier to the other party, at the following address:

                           To CS:
                           CareScience, Inc.
                           3600 Market Street, 6th Floor
                           Philadelphia, PA  19104
                           Phone: (215) 387-9401
                           Facsimile: (215) 387-9406
                           Attention: President

                           To Anchor :
                           INSERT ADDRESS 1
                           INSERT ADDRESS 2
                           INSERT ADDRESS 3
                           Phone: INSERT PHONE
                           Facsimile: INSERT FAX
                           Attention: INSERT CONTACT

         13.6     GOVERNING LAW. This Agreement shall be governed by and
                  construed in accordance with the law of the State of
                  California, without giving effect to conflicts of law
                  principles.
         13.7     TITLES AND HEADINGS. Title and headings to sections,
                  subsections and sub-subsections of this Agreement are for the
                  purposes of reference only and shall not affect the
                  interpretation of this Agreement.
         13.8     COUNTERPARTS. This Agreement may be signed in one or more
                  counterparts, each of which shall be deemed to be an original,
                  but all of which together will constitute one and the same
                  instrument.
         13.9     TAX MATTERS. Nothing in this Agreement shall be construed to
                  require CS or CHCF to take any action that would violate any
                  federal or state law, rule or regulation, including, but not
                  limited to, the rules governing organizations classified as
                  private foundations as set forth in the Internal Revenue Code,
                  and any state laws concerning the operation of charitable
                  trusts or private foundations. CS has the authority to report
                  any payments made hereunder to the Internal Revenue

                                      A-8
<PAGE>

                  Service, and to make any withholdings as required by the
                  Internal Revenue Code or any applicable state law.

         13.10    SURVIVAL. In the event of any expiration or termination of
                  this Agreement, provisions hereof which are intended to
                  continue and survive shall so continue and survive, including,
                  but not limited to, the provisions of Sections 4.3, 7.3, 7.4,
                  8, 9, 10, 11, 12 and 13.

         13.11    ASSIGNMENT. This Agreement and all rights and obligations
                  hereunder may not be assigned or transferred by Anchor, except
                  with the prior written consent of CS.

         13.12    POLITICAL ACTIVITIES. Funds from this Agreement may not be
                  used for any purposes other than those that directly support
                  the project. Prohibited purposes include but are not limited
                  to: to carry out propaganda, or otherwise attempt to influence
                  legislation; to influence the outcome of any specific public
                  election or to carry on directly or indirectly any voter
                  registration drive.

         13.13    USE OF NAME, ACKNOWLEDGEMENT AND PUBLICITY. Anchor may not
                  publish or otherwise disclose in writing or in computer form,
                  and shall use reasonable efforts not to allow any Participant
                  to publish or otherwise disclose in writing or in computer
                  form, any information regarding the project including but not
                  limited to press releases or project results without prior
                  approval by CS and CHCF. CS or CHCF may issue press releases
                  without prior consent of Anchor or Participant so long as any
                  description of Anchor or Participant has been pre-approved,
                  and such description is hereby attached hereto as Exhibit
                  13.13. Anchor may not otherwise use CS's or CHCF's names
                  except as specified in this Agreement. Any publication
                  produced by Anchor that refers to or results from this Project
                  shall include an acknowledgment of CHCF and CS that reads:

                  SUPPORTED BY THE CALIFORNIA HEALTHCARE FOUNDATION, BASED IN
                  OAKLAND, CALIFORNIA. THE FOUNDATION IS A NON-PROFIT
                  PHILANTHROPIC ORGANIZATION WHOSE MISSION IS TO EXPAND ACCESS
                  TO AFFORDABLE, QUALITY HEALTH CARE FOR UNDERSERVED INDIVIDUALS
                  AND COMMUNITIES, AND TO PROMOTE FUNDAMENTAL IMPROVEMENTS IN
                  THE HEALTH STATUS OF THE PEOPLE OF CALIFORNIA. THIS PROJECT
                  WAS MANAGED BY CARESCIENCE, INC., WHICH PROVIDES
                  INTERNET-BASED TOOLS DESIGNED TO IMPROVE THE QUALITY AND
                  EFFICIENCY OF HEALTH CARE. CARESCIENCE'S OBJECTIVE IS TO
                  FACILITATE IMPROVEMENTS IN HEALTH CARE QUALITY AND EFFICIENCY
                  BY USING THE INTERNET TO BECOME THE LEADER IN COLLECTION,
                  ANALYSIS AND EXCHANGE OF COMPREHENSIVE, COMMUNITY-WIDE
                  CLINICAL DATA. CARESCIENCE'S PRODUCTS ALLOW HOSPITAL, HEALTH
                  SYSTEM, HEALTH PLAN, PHYSICIAN AND PHARMACEUTICAL MANUFACTURER
                  USERS TO COST-EFFECTIVELY EVALUATE AND MANAGE THE KEY QUALITY
                  FACTORS IN CARE DELIVERY.

                                      A-9

<PAGE>

IN WITNESS WHEREOF, this Agreement has been executed by each of the parties
effective as of the day and year first written above.

                                                          For CareScience, Inc.

                                                          By:
                                                             ------------------
                                                          Name:
                                                               ----------------
                                                          Its:
                                                              -----------------
                                                          For Anchor

                                                          ----------------------
                                                          By:
                                                             ------------------
                                                          Name:
                                                               ----------------
                                                          Its:
                                                              -----------------

                                                          Tax ID
                                                                ---------------

      Date:       _________________________

                                      A-10

<PAGE>

                                   EXHIBIT 1.7
                                   -----------

                                  DELIVERABLES

INSERT ANCHOR ORGANIZATION NAME

Anchor agrees to professionally and competently complete the following
deliverables to CS' reasonable satisfaction according to the schedule below and
to submit to CS each deliverable by the agreed upon due date.

         DELIVERABLES                              DUE DATE/
                                                   TIMEFRAME

Sign Care Data Exchange Accord                     Completed:INSERT DATE

Enter into Care Data Alliance Agreements          Within 30 days of
as provided by CS with self-selected              execution of this
Santa Barbara Care Data Exchange Members          Agreement

Develop Care Data Alliance Data Security
Policies and Procedures.

Milestone
Deliverable to be submitted

Milestone
Deliverable to be submitted

                                      A-11

<PAGE>

                                  EXHIBIT 1.11

                         CARE DATA ALLIANCE PARTICIPANTS

INSERT ANCHOR ORGANIZATION NAME

LIST PARTICIPANTS HERE

                                      A-12

<PAGE>

                                   EXHIBIT 6.1

                          CARE DATA ALLIANCE AGREEMENT

INSERT ANCHOR ORGANIZATION NAME

                                      A-13

<PAGE>

                                    EXHIBIT 7

                                PAYMENT SCHEDULE
                         INSERT ANCHOR ORGANIZATION NAME

CHCF will make payments to Anchor according to the following Payment Schedule
provided CS certifies to CHCF that (i) Anchor is not in breach of this
Agreement, and (ii) has met all conditions to such payment as set forth herein.
This Agreement comprises payment solely for process and labor-related
deliverables specifically provided for in this agreement and not including
vendor-specific technologies.

Total project costs: not to exceed INSERT MAXIMUM AMOUNT

Payments will be made in three phases:

$xxx,xxx          Initial payment to be made within 30 days of receipt of a
                  fully executed Care Data Alliance Agreement.

$xxx,xxx          Second payment to be made within 30 days of receipt and
                  CS' approval of the "Planning Document" noted in Exhibit 1.7
                  and evidence of compliance with all other Responsibilities as
                  outlined in Exhibit 1.7.

$xxx,xxx          Third payment to be made within 30 days of successful
                  completion of all Responsibilities and Deliverables as
                  outlined in Exhibit 1.7.

Anchor will make payment to contracted Care Data Alliance Participants for the
following amounts according to the Payment Schedule outlined in the Care Data
Alliance Agreement as defined in Exhibit 6.1.

Participant                $xx

Participant                $xx

                                      A-14

<PAGE>

                                  SCHEDULE 1.4

              SOFTWARE PRODUCTS ONLY FOR INTERNAL SYSTEM OR PROCESS

                                      A-15

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