Document:

EXHIBIT
      10.2

    ASSIGNMENT
      AND ASSUMPTION AGREEMENT 

    

    

    This
      ASSIGNMENT AND ASSUMPTION AGREEMENT (the “Assignment”),
      dated
      as of October 25, 2006, by and among Keryx Biopharmaceuticals, Inc., a Delaware
      corporation (the “Assignor”)
      and
      AOI Pharmaceuticals, Inc., a Delaware corporation and wholly-owned subsidiary
      of
      Assignor (the “Assignee”).

    

    WITNESSETH

    

    WHEREAS,
      the
      Assignor entered into a License Agreement (the “Agreement”)
      on
      September 29, 2006 with Kyowa Hakko Kogyo Co., Ltd. (“Kyowa”), a corporation
      formed under the laws of Japan, regarding the compound UCN-01 (capitalized
      terms
      used but not defined herein shall have the meanings ascribed to them in the
      Agreement); 

    

    WHEREAS,
      Section
      25 of the Agreement specifies that the Agreement may not be assigned to a “Third
      Party” by either “Party” without the other “Party’s” prior written consent
      thereto; 

    

    WHEREAS,
      Section
      1.46 of the Agreement provides that a “Third Party” shall not include any
      Affiliate of Assignor or Kyowa; 

    

    WHEREAS,
      Section
      1.1 of the Agreement provides that an “Affiliate” of the Assignor shall mean any
      business entity which controls, is controlled by, or is under common control
      with Assignor, where a corporation or non-corporate business entity shall be
      regarded as in control of another corporation if it owns or directly or
      indirectly controls more than fifty percent (50%) of the voting stock of the
      other corporation; 

    

    WHEREAS,
      Assignee is an Affiliate of Assignor; 

    

    WHEREAS,
      Assignor intends to assign and transfer all rights, benefits, privileges, and
      claims, as well as obligations, duties, and responsibilities pursuant to the
      Agreement (the Assigned
      Rights and Obligations”)
      to the
      Assignee;

    

    WHEREAS,
      the
      Assignee desires, on the terms set forth herein, to assume all of the Assigned
      Rights and Obligations.

    

    NOW,
      THEREFORE BE IT RESOLVED,
      that the
      Assignor and the Assignee agree as follows:

    

    
      	1.  	
              Assignment
                and Assumption.
                

            

    

    

    
      	(a)  	
              Assignor
                hereby assigns to Assignee all of the Assigned Rights and Obligations,
                and
                Assignee hereby assumes all of the Assigned Rights and
                Obligations.

            

    

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

     

    
      	(b)  	
              Assignee
                assumes, and agrees to pay and perform, all unperformed obligations
                of
                Assignor with respect to the Assigned Rights and Obligations, and
                agrees
                to be bound by the provisions of the Agreement, as if it were an
                original
                signatory thereto, and Assignor shall have no further obligations
                under
                the Agreement.

            

    

    

    
      	2.  	
              Binding
                Effect; Successors and Assigns.
                The provisions of this Assignment shall be binding upon and inure
                to the
                benefit of the parties hereto and their respective successors and
                permitted assigns as set forth in the next sentence. This Assignment
                may
                not be assigned by any party hereto without the prior written consent
                of
                each of the other parties hereto.

            

    

    

    
      	3.  	
              Amendment;
                Waiver.
                This Assignment may be amended only by a written instrument signed
                by all
                the parties hereto. No waiver by any party hereto of any provision
                hereof
                shall be effective unless set forth in a writing executed by the
                party so
                waiving.

            

    

    

    
      	4.  	
              Governing
                Law.
                This Assignment shall be governed by and construed in accordance
                with the
                laws of the State of New York (without regard to conflict of law
                principles).

            

    

    

    
      	5.  	
              Counterparts.
                This Assignment may be executed in any number of counterparts, and
                each
                such counterpart shall be deemed to be an original instrument, but
                all
                such counterparts together shall constitute but one
                agreement.

            

    

    

    
      	6.  	
              Entire
                Agreement.
                This Assignment supersedes any other agreement, whether written or
                oral,
                that may have been made or entered into by the parties hereto relating
                to
                the matters contemplated hereby and constitutes the entire agreement
                of
                the parties.

            

    

    
 

    
      
        
        

      

      
        -2-

        
          

        

      

      
        
        

      

    

    

    IN
      WITNESS WHEREOF, the Assignor and the Assignee have caused this Assignment
      and
      Assumption Agreement to be executed by its duly authorized officer as of the
      day
      and year first above written.

    

    

    
      	 	
              ASSIGNOR:

               

              KERYX
                BIOPHARMACEUTICALS, INC.

               

               

              By:/s/
                Michael
                S.
                Weiss                            
                

              
                

              

               

              Name:
                Michael
                S.
                Weiss                      
                

               

              Title:
                Chairman
                and
                CEO                      
                

               

               

            
	 	
              ASSIGNEE:

               

              AOI
                PHARMACEUTICALS, INC.

               

               

              
                By:/s/
                  Michael
                  S.
                  Weiss                            
                  

              

              
                
 

              Name:
                Michael
                S.
                Weiss                       

               

              Title:President                                        

            

    

    

    
      
        
        

      

      
        -3-Exhibit
      10.3

    

    OFFICIAL
      FORM L-2 @ 1976

    
 

    
      GREATER
        DALLAS BOARD OF REALTORS

      

      STATE
        OF
        TEXAS

      COUNTY
        OF
        DALLAS

      

      SHORT
        FORM COMMERCIAL LEASE

      

      

      This
        lease agreement made and entered into by and between

      

      Kenneth
        R. Griffith

      (hereinafter
        referred to as “Landlord”), and

      

      K&B
        Sales, Inc.

      (hereinafter
        referred to as “Tenant”);

      

      WITNESSETH

      

      Landlord
        hereby leases to Tenant, and Tenant hereby takes from Landlord the following
        described premises situated within the County of Dallas, State of
        Texas:

      

      Warehouse
        and office facilities at 11827 Judd Ct. Dallas, TX

      

      together
        with all the rights, privileges, easements and appurtenances belonging to
        or in
        any pertaining to the demised premises for a term of Five
        (5) years
        beginning the 1st
        day of
November
        2003,
        and
        ending the 31st
        day of
October
        2008
        to be
        occupied as OFC/Warehouse
        and not
        otherwise, paying therefor the sum of Seven
        Thousand Five Hundred Dollars ($7,500.00)
        Dollars,
        payable upon the conditions and covenants following:

       

      1. Each
        year
        during the term of this lease, Tenant shall pay real estate taxes assessed
        against the demised premises in an amount equal to the total real estate
        taxes
        assessed against the demised premises in the base year. Each year during
        the
        term of the lease, Tenant shall pay an additional rental, upon receipt of
        statement from Landlord along with tax statements or verification from proper
        authority, his pro rata share of any increase in real estate taxes over the
        base
        year on the property of which the demised premises form a part. Any increase
        in
        real estate taxes for a fractional year shall be prorated. The base year
        shall
        be
        2003
        .
        Tenant
        shall also pay all charges for utility services to the demised
        premises.

      

        
          
            
               

            

            
            

          

          
            
            

            
              

            

          

          
            
            

            
              OFFICIAL
                FORM L-2 @ 1976

            

          

        

      

       

      2. Failure
        of Tenant to surrender the demised premises at the expiration of the lease
        constitutes a holding over which shall be construed as a tenancy from month
        to
        month at a rental of $10,000.00
        per
        month.

      

      3. Rent
        shall be paid in Dallas County, Texas, monthly in advance as the same shall
        become due.

      

      4. Tenant
        has examined and accepts the premises, building, and each appurtenance thereto
        in their present condition as suitable for the purposes for which the same
        are
        leased, and agrees to accept the premises regardless of reasonable deterioration
        between the date of this lease and the date Tenant begins occupying the
        premises.

      

      5. Landlord
        shall maintain in good repair the roof, foundation and exterior walls of
        the
        building. Tenant agrees to give Landlord written notice of defects and notice
        for repairs of the roof, foundation or exterior walls. Landlord shall not
        be
        liable to Tenant for damage caused by the premises being or becoming out
        of
        repair until it has been notified of the necessity of repair by the Tenant
        and
        has had reasonable opportunity to repair the same.

      

      6. Tenant
        shall maintain the premises and equipment, including plate glass, store front
        and entrances. Tenant shall, at its expense, keep the interior of the building,
        including the plumbing, closets, pipes, fixtures and air conditioning equipment,
        if any, in good repair and shall keep water pipes and connections free from
        ice
        and other obstructions. Tenant shall take good care of the premises and its
        fixtures and suffer no waste. If Tenant leases an entire building unit, Tenant
        shall be responsible for keeping the roof clean and downspouts
        open.

      

      All
        alterations, additions and improvements, except trade fixtures and air
        conditioning and heating equipment installed at expense of Tenant, shall
        become
        the property of Landlord and shall remain upon and be surrendered with the
        premises as a part thereof on the termination of the lease.

      

      No
        cooling tower, equipment, or structure of any kind shall be placed on the
        roof
        of the leased premises by Tenant without prior written permission of Landlord.
        If such permission is granted, such work or installation shall be done at
        Tenant’s expense and in such a manner that the roof shall not be damaged
        thereby. If it becomes necessary to remove such cooling tower, equipment
        or
        structure, temporarily, so that repairs to the roof can be made, Tenant shall
        promptly remove and reinstall the cooling tower, equipment or structure at
        Tenant’s expense and repair at Tenant’s expense any damage resulting from such
        removal or reinstallation. Upon termination of this lease, Tenant shall remove
        or cause to be removed from the roof any such cooling tower, equipment or
        structure, if directed to do so by Landlord or Landlord’s agent. Tenant shall
        promptly repair at its expense any damage resulting from such
        removal.

      

      At
        the
        termination of this lease, Tenant shall deliver the premises in good order
        and
        condition, natural deterioration and damage by fire, or other casualty only
        excepted. Any damage caused by the installation or removal of Tenant’s
        equipment, trade fixtures, air conditioning and heating equipment, shall
        be
        repaired at Tenant’s expense prior to the expiration of the lease
        term.

      
        

          
            
              
                 

              

              
              

            

            
              
              

              
                

              

            

            
              
              

              
                

                OFFICIAL
                  FORM L-2 @ 1976

              

            

          

        

      All
        alterations, improvements, additions and repairs made by Tenant shall be
        made in
        a good and workmanlike manner.

      

      7. Tenant
        shall comply with all ordinances of the municipal corporation or other
        governmental authority applicable to such premises because of Tenant’s use of
        the premises. Tenant, at its expense, shall comply with all orders and
        requirements imposed by such governmental authorities during the term of
        this
        lease.

      

      8. Tenant
        shall not assign this agreement or sublet the premises or any part thereof
        or
        make any improvements or alterations in or to the demised premises without
        the
        prior written consent of Landlord, which consent shall not be unreasonably
        withheld. Tenant shall not occupy or allow the premises to be occupied for
        any
        business or purpose deemed extra hazardous because of the threat of fire
        or
        otherwise. If consent is granted to assign or sublet the premises, Tenant
        shall
        remain principal obligor for the fulfillment of each and every condition
        of this
        lease. If consent is granted for the making of improvements or alterations
        to
        the premises, such improvements and alterations shall not commence until
        Tenant
        has furnished to Landlord a certificate of an insurance company showing coverage
        in an amount satisfactory to Landlord and protecting Landlord from liability
        for
        injury to any person and damage to any personal property, on or off the
        premises, in connection with the making of such improvements or
        alterations.

      

      9. In
        the
        event the demised premises are partially damaged or destroyed or rendered
        partially unfit for occupancy by fire or tornado or other casualty, Tenant
        shall
        give immediate notice to Landlord who may repair the damage and restore the
        premises to substantially the condition in which they were immediately prior
        to
        the occurrence of the casualty. Such repairs shall be made at Landlord’s
        expense. Landlord shall allow Tenant a fair reduction of rent during the
        time
        the premises are partially unfit for occupancy. If the premises are totally
        destroyed or deemed by the Landlord to be rendered wholly unfit for occupancy
        by
        fire, tornado or other casualty, or if the Landlord shall decide not to repair
        or rebuild, this lease shall terminate and the rent shall be paid to the
        time of
        such destruction or casualty. 

      

      10. If
        Tenant
        defaults in the performance of any obligations or covenants herein, Landlord
        may
        enforce the performance of this lease in any mode provided by law. This lease
        may be terminated at Landlord’s discretion if such default continues for a
        period of 10 days after Landlord notifies Tenant of such default and of its
        intention to declare the lease terminated. Such notice shall be sent by Landlord
        to Tenant at the demised premises by mail or otherwise. If Tenant has not
        completely removed or cured default within the 10 day period, this lease
        shall
        terminate. Thereafter, Landlord or its agents shall have the right, without
        further notice or demand, to enter the premises and remove all persons and
        property therefrom without being deemed guilty of trespass and without waiving
        any other remedies for arrears of rent or breach of covenant. Landlord or
        Landlord’s agents may resume possession of the premises and relet the same for
        the remainder of the term at the best rent obtainable for the account of
        Tenant,
        who shall make good any deficiency.

      
        

          
            
              
                 

              

              
              

            

            
              
              

              
                

              

            

            
              
              

              
                

                OFFICIAL
                  FORM L-2 @ 1976

              

            

          

        

      In
        addition to the statutory lien, Tenant hereby grants to Landlord a security
        interest in and to all the goods, wares, chattels, implements, fixtures,
        furniture, tools and other personal property which are or may be put on the
        demised premises by Tenant. Tenant shall execute such financing statements
        as
        shall be requested by Landlord in order to perfect Landlord’s security interest
        hereunder. If, because of the breach or default by Tenant of any of Tenant’s
        obligations hereunder, it shall become necessary for the Landlord to employ
        an
        attorney to enforce or defend any of Landlord’s rights or remedies, Tenant shall
        pay to Landlord any reasonable amount incurred by Landlord as attorney
        fees.

      

      11. Landlord
        and its agents shall not be liable to Tenant or to Tenant’s employees, patrons,
        visitors, invitees, or any other persons for any injury to any such persons
        or
        for any damage to personal property caused by any act, omission, or neglect
        of
        Tenant or Tenant’s agents or of any other tenant of the premises of which
        demised premises are a part. Tenant agrees to indemnify and hold Landlord
        and
        its agents harmless from any and all claims for such injury and damage, whether
        the injury occurs on or off the demised premises.

      

      12. Tenant
        shall not post or paint any signs at, on or about the premises or paint the
        exterior walls of the building except with the prior written approval of
        the
        Landlord. Landlord shall have the right to remove any sign or signs in order
        to
        paint the building or premises or to make any repairs or
        alterations.

      

      13. If
        Landlord herein is not the owner of the demised premises, but holds the property
        by virtue of another lease, then this sublease is and shall remain subject
        to
        all terms and conditions of such existing lease of the Landlord so far as
        they
        shall be applicable to the demised premises.

      

      14. If
        Tenant
        becomes bankrupt or makes a voluntary assignment for the benefit of creditors
        or
        if a receiver is appointed for Tenant, Landlord may terminate this lease
        by
        giving five (5) days written notice to the Tenant of its intention to do
        so.

      

      15. If
        the
        whole or any substantial part of the demised premises is taken for any public
        or
        quasi-public use under any governmental law, ordinance or regulation or by
        right
        of eminent domain or should the premises be sold to a condemning authority
        under
        threat of condemnation, this lease shall terminate and the rent shall be
        abated
        during the unexpired portion of the lease effective from the date of the
        physical taking of the premises.

      

      If
        this
        lease is assigned or the premises are sold prior to the termination of the
        lease, Landlord, its assigns, successors, and heirs shall be jointly and
        severally liable for all REALTORS commissions due or to become due hereunder.
        Landlord will not transfer, convey or sell the premises without specific
        written
        agreement with the purchaser that all commissions due or to become due will
        be
        paid to Principal REALTOR when due by purchaser in connection with existing
        leases on the premises at the time the sale occurs.

      
        

          
            
              
                 

              

              
              

            

            
              
              

              
                

              

            

            
              
              

              
                

                OFFICIAL
                  FORM L-2 @ 1976

              

            

          

        

      If,
        on
        account of any breach or default by any party hereto in his or its obligations
        to Principal REALTOR, it shall become necessary for Principal REALTOR to
        employ
        an attorney to enforce or defend any of Principal REALTOR’S rights or remedies
        hereunder and should Principal REALTOR prevail, such parties agree to pay
        Principal REALTOR reasonable attorney fees in connection therewith.

      

      16. No
        waiver
        by Landlord of any default or breach of any term, covenant, condition,
        agreement, provision, or stipulation herein contained shall constitute a
        waiver
        of any subsequent default or breach of the same or any other term, covenant,
        condition, agreement, provision or stipulation hereof.

      

      17. This
        lease constitutes the full and final expression of the agreement between
        the
        parties and it may not be amended except by written instrument signed by
        all the
        parties.

      

      18. SPECIAL
        CONDITIONS:

      

      Tenant
        to pay cost of insurance and provide proof of insurance on building and
        improvement. Tenant deposits from prior lease to carryover to new lease.
        For
        last month rent: $7,000.00. For security deposit:
        $4,250.00.

      

      EXECUTED
        THE 1STday
        of
November,
        2003

       

      
        	 	 	 	 	 
	 	 	 	 	LANDLORD:
	Attest:	 	 	 	 
	 	 	 	 	 
	
                Kenneth
                  Griffith

              	 	
                By:

              	 	Kenneth
                R. Griffith
	
                

              	 	 
                
                Title:

              	 	
                

                Owner/Landlord

              
	 	 	 	 	 

         

        
          	 	 	 	 	 
	 	 	 	 	
                  TENANT:

                
	Attest:	 	 	 	 
	 	 	 	 	 
	
                  
                    Nicholas
                      Holt

                  

                	 	
                  By:

                	 	
                  Nicholas
                    Holt

                
	
                  

                	 	 
                  
                  Title:

                	 	
                  

                  
                    President

                  

                
	 	 	 	 	
                  
 

        

         

         

      

      
        	
                NOTE:

              	
                If
                  this lease agreement is negotiated by Principal REALTOR in cooperation
                  with another REALTOR, Landlord shall be liable for payment of all
                  commissions to Principal REALTOR only, whereupon it shall be protected
                  from any claims from said Cooperating
                  REALTOR.

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