Document:

Form Amendment to Employment Agreement

 Exhibit 10.1 
 FIRST AMENDMENT TO EMPLOYMENT AGREEMENT 
 THIS FIRST AMENDMENT TO EMPLOYMENT AGREEMENT
(the “Amendment”) is made and entered into to be effective this 1st day of September, 2007, by and between PETROHAWK ENERGY CORPORATION, a Delaware corporation (the “Company”), and [EXECUTIVE NAME] (the
“Executive”). 
 WHEREAS, the Company and Executive entered into an Employment Agreement dated July 11, 2006 (the
“Agreement”); 
 WHEREAS, the terms and conditions of the Agreement include retirement benefits and severance pay for the
Executive; 
 WHEREAS, certain portions of such retirement benefits and severance pay may be deferred compensation subject to
Section 409A of the Internal Revenue Code (the “Code”); 
 WHEREAS, the parties desire to amend and restate this
Agreement in order to comply with the provisions of Code § 409A and the Treasury and IRS guidance issued thereunder and to clarify some of the terms and conditions of Executive’s employment with the Company; and 
 WHEREAS, this Amendment is being made within the transition period provided by IRS Notice 2005-1, as extended by IRS Notice 2006-79. 

NOW, THEREFORE, in consideration of the foregoing, the Company and Executive hereby agree as follows: 
 1. Amendment to Paragraph 1. Paragraph 1 of the Agreement is hereby deleted in its entirety and replaced with the following language:

 “1. Term of Employment. The Company shall employ the Executive in the capacity set forth herein for a term of two
(2) years, commencing on the Effective Date and ending on the second anniversary of the Effective Date (such two year period as may be terminated earlier or extended as provided for herein to be referred to herein as the “Term”).
Beginning on the first anniversary date of the Effective Date and on each anniversary date of the Effective Date thereafter, the Term shall be automatically extended one additional year unless this Agreement is terminated pursuant to paragraph 10 of
this Agreement.” 
 2. Amendment to Paragraph 10. The introductory language in paragraph 10 of the Agreement is hereby
deleted in its entirety: 
 “10. Termination of Employment. The Executive’s employment by the Company may be
terminated, without breach of this Agreement, in accordance with the provisions set forth below:” 
 Such deleted language is hereby replaced with the
following language: 
 “10. Termination of Employment. The Executive’s employment by the Company and this Agreement
may be terminated, without breach of this Agreement, in accordance with the provisions set forth below:” 

 3. Amendment to Paragraph 10(a). Paragraph 10(a) of the Agreement is hereby deleted in its
entirety and replaced with the following language: 
 “(a) Death. If the Executive dies during the Term and while in the employ of
the Company, this Agreement shall automatically terminate, and the Company shall have no further obligations to the Executive or his estate except that the Company shall pay to the Executive’s estate any unpaid portion of the Executive’s
Base Compensation and benefits accrued through the date of death, and at the discretion of the Compensation Committee, a bonus, if any. All such payments to the Executive’s estate shall be made in the same manner and at the same time as the
Executive’s Base Compensation would have been paid to him had he not died. In addition, all stock options and other incentive awards held by the Executive will become fully vested and immediately exercisable and all restrictions on any
restricted stock held by the Executive will be removed.” 
 4. Amendment to Paragraph 10(b). Paragraph 10(b) of the
Agreement is hereby deleted in its entirety and replaced with the following language: 
 “(b) Disability. The Company may
terminate the Executive’s employment under this Agreement in the event of the Executive’s disability, which shall be defined in accordance with any disability policy maintained by the Company. In the event the Company does not maintain a
disability policy, it shall be defined as the inability of the Executive, despite any reasonable accommodation required by law, due to bodily injury or disease or any other physical or mental incapacity, to perform the services required hereunder
for a period of 120 consecutive days. In the event of a termination pursuant to this paragraph 10(b), the Company shall be relieved of all of its obligations under this Agreement, except that the Company shall pay to the Executive or his estate in
the event of his subsequent death, any unpaid portion of the Executive’s Base Compensation and benefits accrued through the date of such termination and, at the discretion of the Compensation Committee, a bonus, if any. All such payments to the
Executive or his estate shall be made in the same manner and at the same time as the Executive’s Base Compensation would have been paid to him had he not become disabled. In addition, all stock options and other incentive awards held by the
Executive will become fully vested and immediately exercisable and all restrictions on any restricted stock held by the Executive will be removed.” 
 5. Amendment to Paragraph 10(d). Paragraph 10(d) of the Agreement is hereby deleted in its entirety and replaced with the following language: 
  

	 	“(d)	Termination by the Company Without Cause. The Company may also terminate the Executive’s employment under this Agreement without Cause by providing at least thirty
(30) days’ written notice of such termination to the Executive. A termination of the Executive’s employment under this Agreement by the Company without Cause shall entitle the Executive to payments and other benefits as specified in
paragraph 10(g) or 10(h), as applicable.” 

 6. Amendment to Paragraph 10(e). Paragraph 10(e) of the Agreement is hereby deleted in its
entirety and replaced with the following language: 
  

	 	“(e)	Termination by the Executive for Good Reason. The Executive shall be entitled to terminate his employment with the Company under this Agreement at any time upon thirty
(30) days written notice to the Company for “Good Reason” (defined hereafter). For purposes of this Agreement, “Good Reason” shall mean: 

  

	 	(i)	The material breach by the Company of any of its obligations hereunder that goes uncured thirty (30) days after written notice by Executive to the Company to such effect; or

  

	 	(ii)	A reduction in the Base Compensation and/or target bonus payable to the Executive; or 

  

	 	(iii)	Any material diminution of Executive’s position with the Company including Executive’s status, office, title, responsibilities and reporting requirements; or

  

	 	(iv)	The failure by the Company to continue in effect any compensation or benefit plan in which the Executive participates and which is material to the Executive’s total
compensation unless an equitable arrangement has been made with respect to such plan; or 

  

	 	(v)	Any occurrence which causes the Executive to have, as his principal place of employment, a location other than the metropolitan area of Houston, Texas. 

 A termination of employment under this Agreement by the Executive with Good Reason shall entitle the Executive to payments and other benefits as specified
in paragraphs 10(g) or 10(h), as applicable.” 
 7. Amendment to Paragraph 10(g). Paragraph 10(g) of the Agreement is
hereby deleted in its entirety and replaced with the following language: 
  

	 	“(g)	Termination by the Executive or the Company Upon a Change of Control; Termination Benefits Upon Termination by the Executive or the Company Upon a Change of Control. The
Executive may also terminate his employment under this Agreement within a two-year period after a Change of Control (as defined hereafter) without Good Reason or for Good Reason by providing written notice of such termination to the Company. Unless
this Agreement is earlier terminated due to the death or disability of the Executive in accordance with paragraph 10(a) or paragraph 10(b) of this Agreement, in the event that (i) the Executive terminates his employment under this Agreement
within a two-year period after the occurrence of a Change of Control without Good Reason or for Good Reason, or (ii) the Company terminates the Executive’s employment under this Agreement without Cause within a two-year period after the
occurrence of a Change of Control, then the following shall occur: 

  

	 	(a)	The Company shall pay the Executive any unpaid portion of the Executive’s Base Compensation and benefits accrued through the date of termination; 

	 	(b)	The Company shall pay the Executive an amount equal to the greater of (i) a pro rata amount of the Executive’s targeted bonus for the year in which the date of termination
occurs, or (ii) a bonus for such year as may be determined by the Compensation Committee or the Board in their sole discretion. Such amount shall be paid in the form of a lump sum. The time of payment of such amount shall be as soon as
practicable after the termination of employment, but no later than March 15 of the year immediately following the year of termination; 

  

	 	(c)	The Company shall pay the Executive a lump sum severance payment (which amount shall be paid within five (5) days after the date of termination) equal to the sum of the
following: (i) an amount equal to two (2) times the greater of (A) the Executive’s annual base salary in effect as of date of termination, or (B) the Executive’s annual base salary in effect immediately preceding the
Change of Control; plus (ii) an amount equal to two (2) times the greater of (1) the amount of any cash bonus payable to the Executive for the year in which the date of termination falls (provided that if the Executive’s bonus
for such year has not been determined as of the date of termination, then the amount of the bonus shall be determined as if the Executive earned 100% of the targeted performance bonus for such year, to the extent such target bonus exists) or
(2) the amount of the cash bonus paid to the Executive for services rendered during the year immediately prior to the calendar year in which the Change of Control occurred; 

  

	 	(d)	For a two (2) year period immediately following the termination, the Company shall continue to maintain and pay the premiums for the Executive’s medical and dental
benefits for him and his family with coverage that is at least as favorable as the coverage being provided immediately prior to the termination (if continued coverage is not permitted under the Company’s insurance plans, then the Company will
provide the Executive with substantially similar insurance through another carrier or reimburse the Executive for the full cost of obtaining such insurance which reimbursement amount shall be paid in full within five (5) days of the
Executive’s furnishing the Company with evidence of the cost of such insurance, which evidence must be furnished within thirty (30) days of such cost being paid by the Executive); and 

	 	(e)	All stock options and other incentive awards held by the Executive will become fully vested and immediately exercisable and all restrictions on any restricted stock held by the
Executive will be removed. 

 In addition to the items referenced in (a)-(e) immediately preceding, if prior to the Change
in Control a bonus for the Executive has been determined by the Compensation Committee or the Board for the year immediately preceding the year in which a Change in Control occurs but has not yet been paid, then the Executive shall receive a bonus
payment for such year in the amount so determined. If prior to the Change in Control a bonus for the Executive has not been paid or determined by the Compensation Committee or the Board for the year immediately preceding the year in which the Change
of Control occurs, then the Executive shall receive a bonus payment for such preceding year in an amount equal to the greater of (i) 100% of Executive’s targeted bonus payment for such year or (ii) the bonus for such preceding year
determined after the Change in Control by the Compensation Committee or the Board pursuant to the terms of the bonus plan in effect immediately prior to the Change in Control.” 
 8. Amendment to Paragraph 10(h). Paragraph 10(h) of the Agreement is hereby deleted in its entirety and replaced with the following
language: 
  

	 	“(h)	Termination Benefits Upon Termination by the Company without Cause or Termination by the Executive for Good Reason Not in Connection with a Change of Control. In the event
that (i) the Company terminates the Executive’s employment under this Agreement without Cause as described in paragraph 10(d) above or (ii) the Executive terminates his employment under this Agreement for Good Reason as described in
paragraph 10(e) above, and in each case, at the time of termination, no Change of Control of the Company had occurred within a two-year period prior to the termination or no payments are otherwise required to be made by the Company pursuant to
paragraph 10(g), then the following shall occur: 

  

	 	(a)	The Company shall pay the Executive any unpaid portion of the Executive’s Base Compensation and benefits accrued through the date of such termination, and at the discretion of
the Compensation Committee, a bonus, if any; 

  

	 	(b)	The Company shall pay the Executive an amount equal to the greater of (i) a pro rata amount of the Executive’s targeted bonus for the year in which the date of termination
occurs, or (ii) such bonus for such year as may be determined by the Compensation Committee or the Board in their sole discretion. Such amount shall be paid in the form of a lump sum. The time of payment of such amount shall be as soon as
practicable after the termination of employment, but no later than March 15 of the year immediately following the year of termination; 

	 	(c)	The Company shall pay the Executive a lump sum severance payment (which amount shall be paid within five (5) days after the date of termination) equal to the sum of (i) an
amount equal to one times the greater of (A) the Executive’s annual base salary in effect as of date of termination, or (B) the Executive’s annual base salary in effect immediately preceding the termination; plus (ii) an
amount equal to one (1) times the greater of (1) the amount of any cash bonus payable to the Executive for the year in which the date of termination falls (provided that if the Executive’s bonus for such year has not been determined
as of the date of termination, then the amount of the bonus shall be determined as if the Executive earned 100% of the targeted bonus for such year, to the extent such targeted bonus exists) or (2) the amount of the cash performance bonus paid
to the Executive for services rendered during the calendar year immediately prior to the year in which the termination occurs; 

  

	 	(d)	For a one (1) year period immediately following the termination, the Company shall continue to maintain and pay the premiums for the Executive’s medical and dental
benefits for him and his family with coverage that is at least as favorable as the coverage being provided immediately prior to the termination; provided, however, if continued coverage is not permitted under the Company’s insurance plans, then
the Company will (a) provide the Executive with substantially similar insurance through another insurance carrier or (b) reimburse the Executive for the full cost of obtaining such insurance which reimbursement amount shall be paid within
five (5) days of the Executive’s furnishing the Company with evidence of the cost of such insurance, which evidence must be furnished within thirty (30) days of such cost being paid by the Executive); and 

  

	 	(e)	All stock options and other incentive awards held by the Executive will become fully vested and immediately exercisable and all restrictions on any restricted stock held by the
Executive will be removed.” 

 5. Remaining Provisions. All other provisions of the Agreement shall remain
in full force and effect. In the event there is any conflict between the terms of this Amendment and the Agreement the provisions contained herein shall control. Any defined terms used herein, but not otherwise defined, shall have the meaning
ascribed to them in the Agreement. 

 6. Binding Effect. This Amendment shall be binding upon and inure to the benefit of the
parties hereto and their respective heirs, legal representatives, successors and assigns. 
 7. Counterparts. This Amendment
may be executed in any number of counterparts (including execution by facsimile), each of which shall be deemed to be an original and all of which taken together shall constitute but one and the same instrument, but only one of which need be
produced. 
 8. Governing Law. This Amendment shall be construed in accordance with and governed by the laws of Texas.

 IN WITNESS WHEREOF, the Company and Executive have executed this Amendment effective as of the date first written above.

  

							
	“COMPANY”	 		 	“EXECUTIVE”
			
	 PETROHAWK ENERGY CORPORATION
	 		 	
				
	By:	 	  
	 		 	  

	 Name:
	 	  
	 		 	[Executive]
	 Title:Convertible Promissory Note

 Exhibit 10.1 
 NEITHER THIS NOTE NOR ANY OF THE SECURITIES ISSUABLE HEREUNDER HAS BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), AND MAY NOT BE OFFERED, SOLD OR OTHERWISE TRANSFERRED, PLEDGED OR HYPOTHECATED IN THE
ABSENCE OF A REGISTRATION STATEMENT IN EFFECT WITH RESPECT TO THE SECURITIES, OR DELIVERY TO THE COMPANY OF AN OPINION OF COUNSEL IN FORM AND SUBSTANCE SATISFACTORY TO THE COMPANY THAT SUCH OFFER, SALE OR TRANSFER, PLEDGE OR HYPOTHECATION IS IN
COMPLIANCE WITH THE ACT OR UNLESS SOLD IN FULL COMPLIANCE WITH RULE 144 UNDER THE ACT. 
 CONVERTIBLE PROMISSORY NOTE

  

			
	 $100,000
	 	August 24, 2007

 Duska Therapeutics, Inc. a Nevada Corporation whose address is Two Bala Plaza, Suite 300, Bala
Cynwyd, Pennsylvania 19004 (the “Company”), for value received, hereby promises to pay to ICON Capital Partners, L.P. or their permitted assignees (each, a “Holder” and together, the “Holders”), the
principal amount of One Hundred Thousand Dollars ($100,000) in accordance with the terms hereof. 
 1. Maturity. Except to the extent
converted into Conversion Units (as defined below) pursuant to Section 3 hereof, the principal amount of this Promissory Note (this “Note”) shall be due and payable on November 24, 2007 (the “Maturity
Date”). 
 2. Payments. Except in the event the Holders elect to convert the principal amount hereof pursuant to
Section 3 hereof into Conversion Units pursuant to Section 3 hereof, those amounts shall be paid on the Maturity Date. All payments of principal and other amounts payable on or in respect of this Note or the indebtedness evidenced hereby
shall be made to the Holders in U.S. dollars, by wire transfer, certified check or Company check. This Note may be prepaid by the Company, at any time, in whole or in part, from time to time, without penalty, at the principal amount hereunder.
Payment of this Note shall not be secured by any of the Company’s assets. 
 3. Conversion. At the option of the Holders, upon
the consummation of any equity or equity linked financing of the Company of at least $5,000,000 (the “Offering”), this Note shall be automatically converted into the units of common stock and warrants (the “Conversion
Units”) being offered by the Company pursuant to the Offering (the “Exchange”). The number of Conversion Units to be issued upon conversion shall equal the principal being converted divided by the price per Conversion Unit
in the Offering. The common stock and warrants comprising the Conversion Units shall have the same terms as those offered in the Offering. By electing to convert all or a portion of the principal balance of this Note into Conversion Units, each
Holder shall be deemed to have irrevocably subscribed for Conversion Units. At any time prior to the Exchange, the principal amount of this Note can be fully converted into shares of the Company’s common stock, $.001 par value per share, by
dividing the principal amount under the Note by $0.40, subject to adjustments as provided herein. 
 4. Warrant Coverage. Each Holder
will receive, in the form attached hereto as Exhibit A, a warrant to purchase (the “Warrant”), in accordance with such Holder’s pro rata share, fully paid and nonassessable shares of common stock of the Company at a
price equal to $0.40 (the “Exercise Price”) if exercised before August 24, 2012. 
 5. Registration Rights. In the event that the Company has not repaid this Note by the Maturity Date, the Company shall prepare promptly and file with the Securities and Exchange Commission (the
“SEC”) as soon as practicable, but in no event later than the thirtieth (30th) day 

 
following the Maturity Date (the “Filing Date”), a Registration Statement (the “Registration Statement”) on Form SB-2 (or,
if Form SB-2 is not then available, on such form of Registration Statement as is then available) to effect a registration of all of the securities underlying the Warrants. The Company shall use its best efforts to cause the Registration Statement
required to be filed pursuant to this Section to become effective as soon as practicable, but in no event later than the ninetieth (90th) day (or 120
days if such Registration Statement is reviewed by the SEC) following the Filing Date (the “Registration Deadline”). If the Registration Statement has not been declared effective by the Registration Deadline, the Company shall pay
to the Holders an amount equal to 1.5% of the amount outstanding hereunder for each 30 day period beyond the Registration Deadline, provided that no more than $20,000 in such fees shall be payable . 
 6. Right of First Refusal. At any time while this Note remains outstanding, but in no event later than the date that is six months after the date
hereof, subject to the terms and conditions specified in this Section 7, the Holders shall have a right to participate with respect to the issuance or possible issuance of any equity or equity-linked securities or debt which is convertible into
equity or in which there is an equity component (as the case may be, “Additional Securities”) on the same terms and conditions as offered by the Company to the other purchasers of such Additional Securities. Each time the Company
proposes to offer any Additional Securities, the Company shall make an offering of such Additional Securities to each Holder in accordance with the following provisions: 
 (1) At least 10 days prior to the issuance of any Additional Securities, the Company shall deliver a notice (the “Issuance Notice”) to each Holder stating (a) its bona fide intention to offer
such Additional Securities, (b) the number of such Additional Securities to be offered, (c) the price and terms, if any, upon which it proposes to offer such Additional Securities, and (d) the anticipated closing date of the sale of
such Additional Securities. 
 (2) By written notification received by the Company, within 10 business days after giving of the Issuance
Notice, each Holder may elect to purchase or obtain, at the price and on the terms specified in the Issuance Notice, up to that number of such Additional Securities which equals such Holder’s Pro Rata Amount (as defined below). The “Pro
Rata Amount” for such Holder shall equal that portion of the Additional Securities that the Company proposes to offer which equals the proportion that the number of shares of common stock that such Holder owns or has the right to acquire
bears to the total number of shares of common stock then outstanding (assuming in each case the full conversion, exercise or exchange of all Convertible Securities and Purchase Rights then outstanding). 
 7. Covenants of the Company. 
 (a) The
Company shall not, without the prior written consent of a majority in interest of the Holders (such consent not to be unreasonably withheld), incur or suffer to exist any new indebtedness for borrowed money that ranks senior to this Note.

 (b) The Company shall not, without the prior approval of the Holders, create any sub-committee of the Board of Directors that is permitted
to take action on behalf of the Company without the prior authorization and approval of the Board of Directors. 
  

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 (c) Within 4 days following the execution of and delivery of this Note, the Company shall file with the
Securities and Exchange Commission a statement on form 8-K (including the transaction documents of this financing as exhibits thereto) disclosing the details of this transaction. 
 8. Board Representation. Upon the execution and delivery of this Note, ICON Capital Partners, L.P. shall have the right to appoint and maintain
one member of the Board of Directors of the Company, which appointee shall be subject to the approval of the Board of Directors. 
 9.
Events of Default. The occurrence of any of the following event shall be an Event of Default under this Note: 
 (a) the nonpayment of
any principal, or other amount due under this Note within ten business days of the date such payment is due; 
 (b) the filing by or against
the Company of any proceeding in bankruptcy, receivership, insolvency, reorganization, liquidation, conservatorship, or similar proceeding (and, in the case of any such proceeding instituted against the Company, such proceeding is not dismissed or
stayed within 90 days of the commencement thereof); or 
 (c) the appointment of (or taking possession by) a receiver, liquidator, assignee,
trustee, custodian, or other similar official for the Company or any assignment by the Company for the benefit of creditors, or any levy, garnishment, attachment, or similar proceeding is instituted against any material property of the Company.

 10. Change of Control. Upon a Change of Control of the Company, the Holders shall have the right to cause the Company to repurchase
this Note, at the election of the Company, in cash or shares of common stock of the Company, at an amount equal to 150% of the outstanding principal. For purposes hereof, a “Change of Control” shall be deemed to occur if any person
or any corporation, partnership or trust, limited liability company or other entity controlled by or established for the benefit of such persons) acquires or enters into a binding agreement to acquire, directly or indirectly, more than 50% of the
total voting power of all equity interests of the Company, other than the Offering. 
 11. Adjustment of Exercise Price and Number of
Conversion Units. The number and kind of securities purchasable upon exercise of the Warrants and the Exercise Price shall be subject to adjustment from time to time upon the occurrence of certain events, as follows: 
 (a) Subsequent Equity Sales. If the Company at any time while this Note is outstanding, shall issue or enter into any agreement or understanding to
issue shares of its common stock entitling any Person to acquire shares of common stock, at a price per share less than the Exercise Price (if the holder of the common stock so issued shall at any time, whether by operation of purchase price
adjustments, reset provisions, floating conversion, exercise or exchange prices or otherwise, or due to warrants, options or rights issued in connection with such issuance, be entitled to receive shares of common stock at a price less than the
Exercise Price, such issuance shall be deemed to have occurred for less than the Exercise Price), then, the Exercise Price shall automatically be reduced to such lower price. Such adjustment shall be made whenever such common stock is issued (or
deemed to be issued). The Company shall notify the Holders in writing, no later than the trading day following the issuance of any common stock subject to this section, indicating therein the applicable issuance price, or of applicable reset price,
exchange price and other pricing terms, but failure to provide such notice will not delay or 

  

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affect the reduction of the Exercise Price. If, while this Note is outstanding, the Company enters into any understanding or agreement to issue or sell
securities, then notwithstanding the fact that such actual issuance of common stock occurs after the term of the Note, such issuance will be treated as if it had occurred prior to the expiration of the Note term. 
 (b) Adjustment of Number of Conversion Units. Upon each adjustment of the Exercise Price as provided in this Section 11, the Holder shall
thereafter be entitled to purchase, at the Exercise Price resulting from such adjustment, the number of Conversion Units obtained by multiplying the Exercise Price in effect immediately prior to such adjustment by the number of Conversion Units
purchasable pursuant hereto immediately prior to such adjustment and dividing the product thereof by the Exercise Price resulting from such adjustment. 
 (c) Payment of Exercise Price. The Exercise Price shall be payable (i) in cash or its equivalent, payable by wire transfer of immediately available funds to a bank account specified by the Company or by
certified or bank cashiers’ check in lawful money of the United States of America; (ii) by surrendering to the Company the right to purchase a number of Conversion Units equal to the product obtained by multiplying the number of Conversion
Units to be purchased (including the Conversion Units to be so surrendered) by a fraction, the numerator of which is the Exercise Price and the denominator of which is the Market Price of the common stock on the date of exercise of the Warrant, or
(iii) in any combination of (i) or (ii). “Market Price,” as of any date, (i) means the volume weighted average sale price for the shares of common stock as reported on the New York Stock Exchange for the 5 trading
days immediately preceding such date, or (ii) if the New York Stock Exchange is not the principal trading market for the shares of common stock, the volume weighted average sale prices on the principal trading market for the common stock for
the 5 trading days immediately preceding such date, or (iii) if market value cannot be calculated as of such date on any of the foregoing bases, the Market Price shall be the average fair market value as reasonably determined by an investment
banking firm selected by the Company and reasonably acceptable to the Holders. 
 (d) Notwithstanding the foregoing, no adjustment will be
made under this Section 11 in respect of issuances by the Company of any equity and equity linked securities in connection with: (1) employee/consultant stock or option plans approved by the Board of Directors of the Company, (2) the
exercise, exchange, adjustment or redemption of this Note or (3) the Offering. 
 12. Expenses. The Company agrees to pay all
reasonable expenses, including reasonable attorneys’ fees and legal expenses, incurred by the Holders in relation to due diligence and the preparation of this Note and other investment documentation. 
 13. Miscellaneous. 
 (a)
Notices. Any notice required or permitted to be sent hereunder shall be delivered personally or mailed, registered or certified mail, return receipt requested, or delivered by overnight courier service, or by facsimile, to the intended
recipient’s address set forth below or to such other address as the intended recipient designates by written notice to the other party, and shall be deemed to have been given upon delivery or transmission, if delivered personally or by
facsimile, five days after mailing, if mailed, or one day after delivery to the courier, if delivered by overnight courier service. 
  

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	 If to the Company, to it at:
 Two Bala Plaza

Suite 300
 Bala Cynwyd, Pennsylvania 19004
 Attention: Amir Pelleg, Ph.D.
	  	 With a copy to:
 Drinker Biddle & Reath
LLP
 One Logan Square, 18th and Cherry
Streets
 Philadelphia, PA 19103
 Fax: (215)
988-2757
 Attention: Stephen T. Burdumy, Esq.

		
	If to the Holder, to it at:	  	With a copy to:

 (b) Severability. The provisions of this Note are severable. The invalidity, in whole or in
part, of any provision of this Note shall not affect the validity or enforceability of any other of its provisions. If one or more provisions hereof shall be declared invalid or unenforceable, the remaining provisions shall remain in full force and
effect and shall be construed in the broadest possible manner to effectuate the purposes hereof. The Company and the Holder further agree to replace such void or unenforceable provisions of this Note with valid and enforceable provisions which will
achieve, to the extent possible, the economic, business and other purposes of the void or unenforceable provisions. 
 (c) Modification;
No Waivers. This Note may not be modified or amended unless such modification or amendment is in writing and is signed by the Company and a majority in interest of the Holders. No extension or waiver of any nature shall be deemed to be effective
unless in writing and signed by a majority in interest of the Holders. No extension or waiver, in any one or more instances, shall be deemed to be or construed as a further or continued extension or waiver of any condition or breach of any term,
condition or covenant contained in this Note. 
 (d) Governing Law; Jurisdiction. This Note shall be governed by and construed in
accordance with the laws of the Commonwealth of Pennsylvania without regard to the conflict of laws principles of any jurisdiction. Jurisdiction for the adjudication of any claim or dispute arising out of this Note shall be proper only in the state
or federal courts of the Commonwealth of Pennsylvania, and the Company hereby consents to such jurisdiction and agrees that it shall not be inconvenient and not subject to review by any court other than such courts in the Commonwealth of
Pennsylvania. 
 (e) Waiver of Jury Trial. THE COMPANY, AND BY ACCEPTANCE OF THIS NOTE, EACH HOLDER, HEREBY IRREVOCABLY AND
UNCONDITIONALLY WAIVES, TO THE FULLEST EXTENT SUCH PARTY MAY LEGALLY AND EFFECTIVELY DO SO, TRIAL BY JURY IN ANY SUIT, ACTION OR PROCEEDING ARISING UNDER, RELATING TO OR IN CONNECTION WITH THIS NOTE. 
 (f) Successor and Assigns. This Note shall be binding upon the Company and the Company’s successors and assigns and shall inure to the
benefit of and be enforceable by each person who shall be the holder of this Note from time to time and each such person’s successors and assigns. The Company shall have no right to sell, transfer, assign or otherwise dispose of this Note,
without the prior written consent of the Holders. 
  

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 (g) Replacement of Note. Upon receipt of evidence reasonably satisfactory to the Company of the
loss, theft, destruction or mutilation of this Note and (in the case of loss, theft or destruction) upon delivery of an indemnity agreement (with surety if reasonably required) in an amount reasonably satisfactory to the Company, or (in the case of
mutilation) upon surrender and cancellation of this Note, the Company will issue, in lieu thereof, a new Note of like tenor 
 [Signature Page
to Follow] 
  

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 IN WITNESS WHEREOF, the Company has executed this Note as of the date first written above. 
  

									
	HOLDER:	 		 	COMPANY:
			
	 ICON Capital Partners, L.P.
 1050 Crown
Pointe Parkway
 Suite 200
 Atlanta, GA 30338
	 		 	Duska Therapeutics, Inc.
					
	By:	 	 /s/ Adam Cabibi
	 		 	By:	 	 /s/ Amir Pelleg, Ph.D.

	Name:	 	Adam Cabibi	 		 	Name:	 	Amir Pelleg
	Title:	 	General Partner	 		 	Title:	 	President

  

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 Exhibit A 
  

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Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00129-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00129-of-00352.parquet"}]]