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                             INCENTIVE STOCK OPTION

THESE OPTIONS AND THE COMMON STOCK ISSUABLE UPON THE EXERCISE HEREOF HAVE NOT
BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR ANY STATE
SECURITIES LAW. THESE OPTIONS AND THE COMMON STOCK ISSUABLE UPON THE EXERCISE
HEREOF MAY NOT BE SOLD, OFFERED FOR SALE, PLEDGED OR HYPOTHECATED IN THE ABSENCE
OF A REGISTRATION STATEMENT IN EFFECT UNDER SUCH ACT AND SUCH LAWS WITH RESPECT
TO THESE OPTIONS AND THE COMMON STOCK ISSUABLE UPON THE EXERCISE HEREOF, OR AN
OPINION OF COUNSEL SATISFACTORY TO THE COMPANY THAT SUCH REGISTRATION IS NOT
REQUIRED.

THESE OPTIONS HAVE BEEN ISSUED PURSUANT TO THE COMPANY'S 2000 STOCK OPTION PLAN,
ALL OF THE TERMS OF WHICH ARE INCORPORATED BY REFERENCE HEREIN IN FULL. THIS
OPTION IS INTENDED BY THE COMPANY TO BE AN INCENTIVE STOCK OPTION AS DEFINED IN
THE PLAN AND IS INTENDED TO COMPLY WITH THE REQUIREMENTS OF SECTION 422 OF THE
INTERNAL REVENUE CODE OF 1986, AS AMENDED. THESE OPTIONS ARE EXPRESSLY SUBJECT
TO ALL OF THE TERMS AND CONDITIONS OF THE PLAN, INCLUDING THE RESTRICTIONS ON
TRANSFERABILITY AND EXERCISE.

OPTION CERTIFICATE                                   15,000 COMMON STOCK OPTIONS
NO. 3

                                MORO CORPORATION

                              COMMON STOCK OPTIONS

                  (These Options will be void if not exercised
                    by the Termination Date specified below.)

         1. Options. Subject to the terms and conditions hereof, this certifies
that DOUGLAS AHLE (the "Holder") is the owner of Fifteen Thousand (15,000)
Options (the "Options") of Moro Corporation, a Delaware corporation (the
"Company"). Each Option entitles the Holder to purchase from the Company at any
time prior to 5:00 p.m. on July 31, 2005, the fifth annual anniversary of the
date hereof (the "Termination Date"), one fully paid and non-assessable share of
the Company's Common Stock, par value $.001 per share(the "Common Stock"),
subject to adjustment as provided in Section 8 hereof.

         2. Option Price. The Options shall be exercised by delivery to the
Company (prior to the Termination Date) of the option price for each share of
Common Stock being purchased hereunder (the "Option Price"), this Certificate,
and the completed Election To Purchase Form which is attached hereto. The Option
Price shall be $.75 per share of Common Stock. The Option Price shall be subject
to adjustment as provided in Section 8 hereof. The Option Price is payable
either in cash or by certified check or bank draft payable to the order of the
Company.

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         3. Exercise. Upon the surrender of this Certificate and payment of the
Option Price as aforesaid, the Company shall issue and cause to be delivered
with all reasonable dispatch to or upon the written order of the Holder and in
such name or names as the Holder may designate, a certificate or certificates
for the number of full shares of Common Stock so purchased upon the exercise of
any Option. Such certificate or certificates shall be deemed to have been issued
and any person so designated to be named therein shall be deemed to have become
a holder of record of such Common Stock on and as of the date of the delivery to
the Company of this Certificate and payment of the Option Price as aforesaid.
If, however, at the date of surrender of this Certificate and payment of such
Option Price, the transfer books for the Common Stock purchasable upon the
exercise of any Option shall be closed, the certificates for the Common Stock in
respect to which any such Option are then exercised shall be issued and the
owner of such Common Stock shall become a record owner of such Common Stock on
and as of the next date on which such books shall be opened, and until such date
the Company shall be under no duty to deliver any certificate for such Common
Stock.

         4. Partial Exercise. The rights of purchase represented by the Options
shall be exercisable, at the election of the Holder, either as an entirety, or
from time to time for any part of the Common Stock specified herein and, in the
event that the Options are exercised with respect to less than all of the Common
Stock specified herein at any time prior to the Termination Date, a new
Certificate will be issued to the Holder for the remaining number of Options not
so exercised.

         5. Termination Date. All of the Options must be exercised in accordance
with the terms hereof prior to the Termination Date. At and after the
Termination Date any and all unexercised rights hereunder shall become null and
void and all such unexercised Options shall without any action on behalf of the
Company become null and void.

         6. Plan Provisions. This Option has been issued pursuant to the
Company's 2000 Stock Option Plan ("Plan"), the terms and conditions of which are
hereby incorporated by reference in full. This Option is intended to be an
incentive stock option as defined in the Plan and is intended to comply with the
requirements of Section 422 of the Internal Revenue Code of 1986, as amended.
Among other things, and notwithstanding anything else set forth herein, the
Options are subject to the following:

            a. The Options may not be pledged, assigned or transferred for any
reason during the Holder's lifetime, and any attempt to do so shall be void and
the Options shall be forfeited.

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            b. No Option shall be transferable otherwise than by will or the
laws of descent and distribution and, during the lifetime of the Holder, shall
be exercisable only by the Holder. Upon the death of the Holder, the person to
whom the rights have passed by will or by the laws of descent and distribution
may exercise the Options only in accordance with this Section 6.

            c. If the Holder ceases to be employed by the Company by reason of
death, any Option held by the Holder may thereafter be exercised, to the extent
exercisable at the time of death, by the legal representative of the Holder
until the earlier to occur of (a) the expiration of a period of six months from
the date of death or (b) the Termination Date.

                           d. If the Holder ceases to be employed by the
Company  for any reason  whatsoever  other than  death,  including  by reason of
disability or retirement,  or  termination of employment  with or without cause,
including voluntary  resignation,  the Options held by the Holder may thereafter
by  exercised  by  the  Holder  (or,  where  appropriate,   the  Holder's  legal
representative), to the extent exercisable at the time of termination, until the
earlier to occur of (a) the  expiration  of the period of three  months from the
date of termination or (b) the Termination Date; provided,  however, that if the
Holder dies during the three-month  period after such termination of employment,
the Option may be exercised only until the end of such three-month period.

            e. Notwithstanding any other provision of the Plan or this Option
Certificate, (a) if the Holder ceases to be an employee of the Company by action
of the Company pursuant to the cause termination provisions of any applicable
employment or other agreement, or (b) if the Holder ceases to be an employee of
the Company for any reason whatsoever and the Company makes a determination that
the Holder (1) has engaged in any type of disloyalty to the Company, including
without limitation, fraud, embezzlement, theft, or dishonesty in the course of
the Holder's relationship or affiliation with the Company, or (2) has been
convicted of a felony or other crime involving a breach of trust or fiduciary
duty owed to the Company, or (3) has made an unauthorized disclosure of trade
secrets of confidential information of the Company, or (4) has breached any
confidentiality agreement or non- competition agreement with the Company in any
material respect, then, at the election of the Company, all unexercised Options
held by the Holder (whether or not then exercisable) shall be terminated. In the
event of such an election by the Company, in addition to immediate termination
of all unexercised Options, the Holder shall forfeit all Common Stock for which

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the Company has not yet delivered stock certificates to the Holder and the
Company shall refund to the Holder the exercise price paid to it upon exercise
of the Options with respect to such Common Stock. Notwithstanding anything to
the contrary herein, the Company may withhold delivery of stock certificates
pending the resolution of any inquiry that could lead to a finding resulting in
forfeiture.

            f. For the purposes of subsections c.,d. and e. above, the term
Company shall include but not be limited to the Company's subsidiary, J.M. Ahle
Co., Inc.

         7. Lost, Mutilated Certificate. In case this Common Stock Option
Certificate shall become mutilated, lost, stolen or destroyed, the Company shall
issue in exchange and substitution for and upon cancellation of the mutilated
certificate, or in lieu of and in substitution for the Certificate lost, stolen,
or destroyed, a new Certificate of like tenor and representing an equivalent
right or interest, but only upon receipt of evidence satisfactory to the Company
of such loss, theft or destruction of such certificate and indemnity, if
requested, also satisfactory to the Company.

         8. Adjustments. Subject and pursuant to the provisions of this Section
8, the Option Price and number of shares of Common Stock subject to the Options
shall be subject to adjustment from time to time only as set forth hereinafter:

            a. In case the Company shall declare a Common Stock dividend on the
Common Stock, then the Option Price shall be proportionately decreased as of the
close of business on the date of record of said Common Stock dividend in
proportion to such increase of outstanding shares of Common Stock.

            b. If the Company shall at any time subdivide its outstanding Common
Stock by recapitalization, reclassification or split-up thereof, the Option
Price immediately prior to such subdivision shall be proportionately decreased,
and, if the Company shall at any time combine the outstanding shares of Common
Stock by recapitalization, reclassification, or combination thereof, the Option
Price immediately prior to such combination shall be proportionately increased.
Any such adjustment to the Option Price shall become effective at the close of
business on the record date for such subdivision or combination. The Option
Price shall be proportionately increased or decreased, as the case may be, in
proportion to such increase or decrease, as the case may be, of outstanding
shares of Common Stock.

            c. Upon any adjustment of the Option Price as hereinabove provided,
the number of shares of Common Stock issuable upon exercise of the Options
remaining unexercised immediately prior to any such adjustment, shall be changed

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to the number of shares determined by dividing (i) the appropriate Option Price
payable for the purchase of all shares of Common Stock issuable upon exercise of
all of the Options remaining unexercised immediately prior to such adjustment by
(ii) the Option Price per share of Common Stock in effect immediately after such
adjustment. Pursuant to this formula, the total sum payable to the Company upon
the exercise of the Options remaining unexercised immediately prior to such
adjustment shall remain constant.

            d. (i) If any capital reorganization or reclassification of the
capital stock of the Company, or consolidation or merger of the Company with
another corporation, person, or entity, or the sale of all or substantially all
of its assets to another corporation, person, or entity, shall be effected in
such a way that holders of Common Stock shall be entitled to receive stock,
securities, cash, property, or assets with respect to or in exchange for Common
Stock, and provided no election is made by the Company pursuant to subsection
(ii) hereof, then, as a condition of such reorganization, reclassification,
consolidation, merger or sale, the Company or such successor or purchasing
corporation, person, or entity, as the case may be, shall agree that the Holder
shall have the right thereafter and until the Termination Date (subject to all
of the other terms and conditions hereof) to exercise such Options for the kind
and amount of stock, securities, cash, property, or assets receivable upon such
reorganization, reclassification, consolidation, merger, or sale by a holder of
the number of shares of Common Stock for the purchase of which such Options
might have been exercised immediately prior to such reorganization,
reclassification, consolidation, merger or sale, subject to such subsequent
adjustments which shall be equivalent or nearly equivalent as may be practicable
to the adjustments provided for in this Section 8.

               (ii) Notwithstanding subsection (i) hereof and in lieu thereof,
the Company may elect by written notice to the Holder hereof, to require the
Holder to exercise all of the Options remaining unexercised prior to any such
reorganization, reclassification, consolidation, merger or sale. If the Holder
shall not exercise all or any part of the Options remaining unexercised prior to
such event, such unexercised Options shall automatically become null and void
upon the occurrence of any such event, and of no further force and effect. The
Common Stock issued pursuant to any such exercise shall be deemed to be issued
and outstanding immediately prior to any such event, and shall be entitled to be
treated as any other issued and outstanding share of Common Stock in connection
with such event. If an election is not made by the Company pursuant to this
subsection (ii) in connection with any such event, then the provisions of
subsection (i) hereof shall apply to such event.

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            e. Whenever the Option Price and number of shares of Common Stock
subject to this Option is adjusted as herein provided, the Company shall
promptly mail to the Holder of this Option a statement signed by an officer of
the Company setting forth the adjusted Option Price and the number of shares of
Common Stock subject to this Option, determined as so provided.

            f. This form of Certificate need not be changed because of any
adjustment which is required pursuant to this Section 8. However, the Company
may at any time in its sole discretion (which shall be conclusive) make any
change in the form of this Certificate that the Company may deem appropriate and
that does not affect the substance hereof; and any Certificate thereafter
issued, whether in exchange or substitution for this Certificate or otherwise,
may be in the form as so changed.

         9. Reservation. There has been reserved, and the Company shall at all
times keep reserved out of the authorized and unissued shares of Common Stock, a
number of shares of Common Stock sufficient to provide for the exercise of the
right of purchase
represented  by the Options.  The Company agrees that all shares of Common Stock
issued upon  exercise  of the  Options  shall be, at the time of delivery of the
Certificates for such Common Stock,  validly issued and outstanding,  fully paid
and non-assessable.

         10. Fractional Shares. The Company shall not issue any fractional
shares of Common Stock pursuant to any exercise of any Option and shall pay cash
to the Holder in lieu of any such fractional shares.

         11. No Right. The Holder shall not be entitled to any of the rights of
a shareholder of the Company prior to the date of issuance of the Common Stock
by the Company pursuant to an exercise of any Option.

         12. Securities Laws. As a condition to the issuance of any Common Stock
pursuant to the Options, the holder of such Common Stock shall execute and
deliver such representations, warranties, and covenants, that may be required by
applicable federal and state securities law, or that the Company determines is
reasonably necessary in connection with the issuance of such Common Stock. In
addition, the certificates representing the Common Stock shall contain such
legends, or restrictive legends, or stop transfer instructions, as shall be
required by applicable Federal or state securities laws, or as shall be
reasonably required by the Company or its transfer agent.

         13. Early Disposition of Common Stock. The Holder hereby acknowledges
and agrees that if the Holder disposes of any Common Stock received under this
Option within two years from date of grant or one year after such Common Stock
was transferred to the Holder upon exercise of this Option, the Holder will
notify the Company in writing within thirty days after the date of such
disposition. The Holder acknowledges that disposition by the

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Holder within such two year period from the date of grant and one year from the
date of exercise of this Option would disqualify the Holder from capital gain
treatment for any gain realized upon such disposition.

         14. Applicable Law. The Options and this Certificate shall be deemed to
be a contract made under the laws of the State of Delaware and for all purposes
shall be construed in accordance with the laws thereof regardless of its choice
of law rules.

         IN WITNESS WHEREOF, MORO CORPORATION, has executed and delivered this
Option Certificate and caused its corporate seal to be affixed hereto as of the
date written below.

                                                MORO CORPORATION

Corporate Seal                              By: /s/ David W. Menard
                                                --------------------------------
                                                David W. Menard,
                                                Chairman

Dated: August 1, 2000

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MORO CORPORATION
Suite 240, Bala Pointe Office Centre
111 Presidential Boulevard
Bala Cynwyd, PA 19004
Attn: David W. Menard,
      Chairman

                              ELECTION TO PURCHASE

         The undersigned hereby irrevocably elects to exercise the right of
purchase represented by the attached Option Certificate No. ______ of the
Company. The undersigned desires to purchase shares of Common Stock provided for
therein and tenders herewith full payment of the Option Price for the shares of
Common Stock being purchased, all in accordance with the Certificate. The
undersigned requests that a Certificate representing such shares of Common Stock
shall be issued to and registered in the name of, and delivered to, the
undersigned at the following address: _________________________________________
_______________________________________________________________________________.
If said number of shares of Common Stock shall not be all the shares purchasable
under the Certificate, then a new Common Stock Option Certificate for the
balance remaining of the shares of Common Stock purchasable shall be issued to
and registered in the name of, and delivered to, the undersigned at the address
set forth above.

Dated:             , 20                Signature:
      -------------    --                        ----------------------------

                                        8<PAGE>
                                                                     EXHIBIT 4.1
                                                                     -----------

                                 AMENDMENT NO. 1
                             DATED NOVEMBER 14, 2000
                                     TO THE
                      AMENDED AND RESTATED RIGHTS AGREEMENT
                                     BETWEEN
                            NEOSE TECHNOLOGIES, INC.
                                       AND
                    AMERICAN STOCK TRANSFER AND TRUST COMPANY

         THIS AMENDMENT NO. 1, dated November 14, 2000, to the AMENDED AND
RESTATED RIGHTS AGREEMENT between NEOSE TECHNOLOGIES, INC. and AMERICAN STOCK
TRANSFER AND TRUST COMPANY dated as of DECEMBER 3, 1998.

         WHEREAS, Neose Technologies, Inc. ("Neose") and American Stock Transfer
and Trust Company ("ASTT") entered into a Rights Agreement, dated as of December
3, 1998 (the "Agreement") dealing with, among other things, certain rights of
the holders of Neose Common Stock; and

         WHEREAS, Neose has entered into an agreement with LeRoy C. Kopp, Kopp
Investment Advisors, Inc. and Kopp Holding Company (collectively, "Kopp") dated
November 14, 2000 (the "Letter Agreement") under which the Company, in exchange
for other consideration, has agreed to permit Kopp not to become an "Acquiring
Person", as defined under the Agreement, subject to the terms and conditions of
the Agreement and the Letter Agreement; and

         WHEREAS, to implement the requirements of the Letter Agreement, Neose
and ASTT, pursuant to Section 26 of the Agreement, have agreed to amend the
Agreement as set forth herein.

         NOW THEREFORE, the parties intending to be legally bound, agree as
follows:

         1. Representations and Warranties. The Company represents and warrants
to the Rights Agent that:

             (a)  to the best knowledge of the Company, a Distribution Date has
                  not occurred prior to the effective date hereof, and

             (b)  this Amendment is authorized pursuant to the requirements of
                  Section 26 of the Agreement, having been approved by the
                  Company's Directors.

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         2. Amendment of Section 1(a). The definition of "Acquiring Person" set
forth in Section 1, paragraph (a) of the Rights Agreement, is amended by adding
a new clause at the end of the definition reading as follows:

                  ; and provided, however, that Kopp Investment Advisors, Inc.,
                  a Minnesota corporation, on its own behalf and on behalf of
                  LeRoy C. Kopp, Kopp Emerging Growth Fund, and Kopp Holding
                  Company, joint filers of a Schedule 13G (and collectively
                  referred to herein as "Kopp") shall not be an Acquiring Person
                  unless and until Kopp (i) is the Beneficial Owner of 20% or
                  more of the shares of Common Stock then outstanding, or (ii)
                  is the Beneficial Owner of 15% or more of the shares of Common
                  Stock then outstanding and is not permitted to file a Schedule
                  13G, in lieu of Schedule 13D, pursuant to the Securities
                  Exchange Act of 1934 and the rules and regulations promulgated
                  thereunder.

         3. No Other Changes. Except as specifically amended by this Amendment,
all other provisions of the Agreement remain in full force and effect. This
Amendment shall not constitute or operate as a waiver of, or estoppel with
respect to, any provisions of the Agreement by any party hereto. Capitalized
terms used and not otherwise defined herein will have the meanings ascribed
thereto in the Agreement.

         4. Counterparts. This Amendment may be executed in one or more
counterparts, each of which shall be deemed an original, but all of which
together shall constitute one and the same agreement.

         IN WITNESS WHEREOF, the parties have caused this Amendment No. 1 to be
duly executed, all as of the date first written above.

                                 NEOSE TECHNOLOGIES INC.

                                 By: /s/ P. Sherrill Neff
                                     -------------------------
                                       P. Sherrill Neff
                                       President and Chief Operating Officer

                                 AMERICAN STOCK TRANSFER AND
                                 TRUST COMPANY

                                 By: /s/ Herbert J. Lemmer
                                     ------------------------
                                       Herbert J. Lemmer
                                       Vice President

                                      -2-

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