Document:

Option issued to Triax Capital Management, Inc.

 EXHIBIT 10.17 
  
 STOCK OPTION AGREEMENT 
  
 THIS STOCK OPTION is granted and effective as of August 23, 2004 (the “DATE OF GRANT”), by SHIPROCK, INC., a Nevada Corporation (the
“OPTIONOR” or “SHIPROCK”), and this STOCK OPTION AGREEMENT (the “AGREEMENT”) is executed, effective as of the DATE OF GRANT, by and between the OPTIONOR and TRIAX CAPITAL MANAGEMENT, INC. (the “OPTIONEE”)

  
 RECITALS 
  
 A. OPTIONOR is desirous to grant this OPTION as a consideration and
inducement to OPTIONEE for providing certain services to SHIPROCK. The OPTIONOR has designated the OPTIONEE to receive a Stock Option pursuant to certain terms and conditions outline below. 
  
 NOW, THEREFORE, THE PARTIES HERETO COVENANT AND AGREE AS FOLLOWS: 

 
 1. 
  
 Number of Shares Subject to Option and Option Price 
  
 The OPTIONOR hereby grants to the OPTIONEE a Stock Option (The “OPTION”) to acquire from the OPTIONOR a total of
Fifty Thousand (50,000) Shares of the $.001 par value Common Stock of SHIPROCK, Inc., a Nevada corporation, at the exercise price of $1.00 per share for the first Twenty Five Thousand (25,000) Shares and $2.00 per share for the second Twenty Five
Thousand (25,000) Shares. The OPTION shall be subject to all of the terms and conditions contained herein. The OPTIONEE, concurrent with the executions of this Option Agreement will pay a non-refundable deposit in the amount of One Thousand ($1,000)
Dollars to the OPTIONOR. Said deposit will apply to the purchase of the shares at such time as the OPTIONOR exercises this OPTION. In the event the OPTION is not exercised, OPTIONOR will retain said deposit as liquidated damages. 
  
 2. 
  
 Terms of the Option 
  
 The OPTION shall be subject to the following terms and conditions: 
  
 2.1 The OPTION to purchase Fifty Thousand (50,000) shares of common stock of SHIPROCK shall be able to be exercised in all
or in part. 
  
 a. This Option Agreement cannot be executed until
such time as the proposed reverse merger between a subsidiary of Shiprock, Inc and Duska Scientific, Inc. has been finalized. 
  

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 b. This OPTION is granted to OPTIONEE as a consideration for services rendered in connection with the
proposed transaction between the OPTIONOR and Duska Scientific, Inc. All or a portion of this stock purchase option may be exercised by the OPTIONEE, by the delivery of a cashiers check or certified funds wired to the OPTIONOR. The net funds
received by OPTIONOR will be divided by $1.00, up to $25,000 or $2.00 up to $50,000 depending on the date of exercise and this will represent the number of options being exercised by the OPTIONEE and this number of shares will be delivered to
OPTIONEE, pursuant to the receipt of an Investment Letter, a Stock Subscription Agreement and the submission of a written Notice of Intent to Exercise an Option, attached hereto as Exhibit ”A”. All funds in the form of the initial deposit
paid to the OPTIONOR by the OPTIONEE will be credited toward the exercise of the Option on the same basis of $1.00 or $2.00 per share depending on the exercise price. 
  
 2.2 The OPTION shall vest and thereby become exercisable subject to the events specified in Section 2.1 (a and b) above.

  
 2.3 The OPTION may, subject to any limitations set forth in
this Agreement, be exercised at any time and from time to time, subject to the terms, conditions and events specified in Section 2.1 (a and b) above. 
  
 2.4 The OPTION must be exercised, if at all, as to a whole number of shares. 
  
 2.5 The term of the OPTION will be for a period of Three Years (3) from the date of execution. 
  
 2.6 Prior to or after this OPTION has been exercised by the OPTIONOR and the
shares of common stock underlying this OPTION or issued pursuant to exercise of the OPTION, shall at the sole discretion of the OPTIONOR be included in any subsequent registration statement filed by the OPTIONOR with the Securities Exchange
Commission. 
  
 2.7 Any shares of Common Stock of SHIPROCK
purchased pursuant to exercise of a portion of the OPTION from the OPTIONOR, shall not be subject to repurchase by the OPTIONOR or SHIPROCK. 
  
 2.8 The OPTION to purchase up to a total of Fifty Thousand (50,000) shares of common stock of SHIPROCK from the OPTIONOR, or any portion of the OPTION not
previously exercised, may not be canceled if the terms and conditions of this Agreement are not met. 
  
 3. 
  
 Limitations on Exercisability of the Option 
  
 The exercise of the OPTION hereby granted, shall be subject to all of the terms and conditions of this Agreement, including, without limitation, the provisions relating to termination of the OPTION in the event of the demise, the disability
or the provisions relating to adjustments to and/or cancellation of the OPTION as specified in this Agreement. 
  

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 4. 
  
 Exercise of the Option 
  
 The OPTION shall be exercised by: (a) delivering to the OPTIONOR a written notice in the form of the document attached hereto as Exhibit ”A”,
specifying the number of shares of Common Stock for which exercise is made and the option price or prices applicable thereto, (b) tendering full payment of the Option Price for the shares for which exercise is made (and any payment with respect to
withholding requested by the OPTIONOR pursuant to Section 13 below, (c) if required by ESCROW AGENT, at the OPTIONEE’S expense, a legal opinion letter, satisfactory in form and substance to the required by a legal representative of the
OPTIONOR, to the effect that the exercise of the OPTION by the OPTIONEE and the acquisition of the shares of the SHIPROCK’S Common Stock from the OPTIONOR, pursuant thereto may be effected without registration of such stock under the Securities
Act of 1933, as amended (the “1933 Act”), or any applicable state securities laws 
  
 Within Five (5) business days after the OPTION is exercised and funds are received in the bank account of the OPTIONOR or the amount of the deposit(s) equals the exercise price as a credit, a certificate for the
shares of Common Stock for which exercise of the OPTION was made, shall be delivered to the OPTIONEE. Unless the OPTION has expired or a portion of the OPTION has not been exercised in full, the OPTIONOR agrees to deliver to the OPTIONEE, a new
Stock Option document covering the balance of the shares of Common Stock covered by the OPTION for which exercise has not been made. The OPTIONOR and the OPTIONEE agree to execute a new Stock Option Agreement, each of such documents to be upon terms
and conditions identical to those of this OPTION and Agreement (except as to the number of shares of Common Stock subject thereto). In lieu of surrendering this OPTION and Agreement after a portion of the Fifty Thousand (50,000) shares have been
exercised, the OPTIONOR, in the case of a partial exercise of the OPTION, an appropriate notation, initialed by the OPTIONOR and the OPTIONEE, may be affixed hereto. 
  
 5. 
  
 Transferability of the Option 
  
 The OPTION shall be transferable or exercisable by any person other than the OPTIONEE, without prior written approval of the OPTIONOR. 
  
 6. 
  
 Warranties and Representations of the Optionee 
  
 By executing this Agreement, the OPTIONEE accepts the OPTION and represents and warrants to the OPTIONOR and covenants and
agrees with the OPTIONOR as follows: 
  
 6.1 The OPTIONEE agrees
to abide by all of the terms and conditions of the OPTION and this Agreement. 
  

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 6.2 The OPTIONEE recognizes, agrees and acknowledges that no registration statement under the 1933 Act,
or under any state securities laws, has been or will be filed with respect to the OPTION or any shares of Common Stock acquired upon exercise of this OPTION. These shares of SHIPROCK being issued and transferred to OPTIONEE pursuant to the exercise
of the Stock OPTION, by SHIPROCK, are being done pursuant to available exemptions. These shares are deemed to be restricted, non-transferable and non-saleable. 
  

6.3 The OPTIONEE agrees not to sell, transfer or otherwise dispose of the any shares of Common Stock of SHIPROCK acquired upon exercise of the OPTION,
except as specifically permitted by exemptions available, the filing of a registration statement and any applicable state and federal securities laws. 
  
 7. 
  
 Indemnification by the Optionee 
  
 The OPTIONEE agrees to indemnify the OPTIONOR, hold OPTIONOR harmless from and against any loss, claim or liability, including attorney’s fees or other legal expenses incurred in the defense thereof, incurred by
the OPTIONOR, as a result of any breach by the OPTIONEE of, or any inaccuracy in, any representation, warranty, covenant or other provision contained in this OPTION. 
  
 8. 
  
 Access to Information 
  
 The OPTIONOR agrees to make available to the OPTIONEE upon written request, such information regarding SHIPROCK that has in the past or is from time to
time hereafter made generally available to its shareholders, prospective shareholders or at some future date on file with the Securities Exchange Commission. 
  
 9. 
  
 No Right to Employment 
  
 Nothing herein shall confer upon the OPTIONEE the right to employment by the OPTIONOR or SHIPROCK, nor affect any right, which SHIPROCK or the OPTIONOR may now or hereafter have to terminate the OPTIONOR as a
consultant and advisor to SHIPROCK. 
  
 10. 
  
 Rights as Shareholder 
  
 The OPTIONEE shall have no rights as a shareholder of SHIPROCK on account of
the OPTION nor on account of shares of Common Stock of the SHIPROCK, which will be acquired upon exercise of the OPTION (but with respect to which no certificates have been delivered to the OPTIONEE). 
  

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 11. 
  
 Tax Withholding 
  
 If, in connection with the exercise of the OPTION or any sale, transfer or other disposition of any of the shares of Common Stock of SHIPROCK acquired
from the OPTIONOR upon exercise of the OPTION, the OPTIONOR may be required by applicable federal, state or local law to withhold any amount on account of income or similar taxes, the OPTIONEE agrees to pay to the OPTIONOR upon request the amount
required to be withheld. 
  
 12. 
  
 Further Assurances 
  
 The OPTIONEE agrees from time to time to execute such additional documents as
the OPTIONOR may reasonably require in order to effectuate the purposes of the this Agreement. 
  
 13. 
  
 Binding Effect

  
 This Agreement shall be binding upon the OPTIONEE and his
or her heirs, successors and assigns, including any Qualified Successor in interest of the OPTIONEE. 
  
 14. 
  
 Entire Agreement; Modifications 
  
 This OPTION
and Agreement constitutes the entire agreement and understanding between the OPTIONOR and the OPTIONEE regarding the subject matter hereof. No waivers, alterations or modifications of the OPTION or this Agreement shall be valid unless in writing and
duly executed by the party against whom enforcement of such waiver, alteration or modification is sought. The failure of any party to enforce any of its rights against the other party for breach of any of the terms of the OPTION or this Agreement
shall not be construed a waiver of such rights as to any continued or subsequent breach. 
  
 15. 
  
 Governing Law

  
 The laws of the State of Nevada shall govern the OPTION
and this Agreement. 
  

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 IN WITNESS WHEREOF, the parties have executed this Agreement as of the day and year first above written.

  

									
	 “OPTIONEE”
	 	 	 	 “OPTIONOR”

					
	By:	 	 /s/ Joseph R. Edington
	 	 	 	 By:
	 	 /s/ Tommy Gropp

	 Triax Capital Management, Inc.
 Joseph R. Edington, President
	 	 	 	 Shiprock, Inc.
 Tommy Gropp, President

  

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 EXHIBIT A 

 
 NOTICE OF INTENT TO EXERCISE STOCK OPTION 
  
 TRIAX CAPITAL MANAGEMENT, INC. 
  
 STOCK OPTION AGREEMENT 
  

	To:	SHIPROCK, Inc 

  
 Please be advised that the undersigned hereby exercises the OPTION to purchase shares of the $.001 par value Common Stock of SHIPROCK, Inc., granted to
the undersigned pursuant to the terms of a Stock Option Agreement (the “Agreement”) dated                     , 2004. 
  
 I/We hereby elect to purchase
                     shares of restricted Common Stock of SHIPROCK, INC. (the “Shares”), at
$.             per share, pursuant to the terms and conditions of the OPTION Agreement. Prior deposits to be credited, certified check or wire transfer in the amount of
                                    
($                    ) dollars, the aggregate OPTION price for
                                 shares for which exercise is hereby made,
accompanies this notice. 
  
 The undersigned acknowledges that the
Shares have not been registered under the Securities Act of 1933 or the securities laws of any state, and therefore, the ability of the undersigned to sell or otherwise dispose of the Shares will be subject to the terms and conditions specified
under available exemptions pursuant to either Rule 144 or Rule 144(k) of the Securities Act of 1933 or the filing of a registration statement by SHIPROCK, Inc. or its successor in interest. 
  
 Date:
                                 ,
200        . 
  

	
	 Triax Capital Management, Inc., OPTIONEE

	
	 

  

 7Form of Registration Rights Agreement

  
 EXHIBIT 10.18

  
 FORM OF REGISTRATION RIGHTS AGREEMENT

  
 THIS REGISTRATION RIGHTS AGREEMENT (this
“Agreement”) is made and entered into as of August 30, 2004, by and among DUSKA THERAPEUTICS, INC., a Nevada corporation (the “Company”), and those shareholders of the Company, appearing as signatories hereto (each, a
“Shareholder” and collectively, the “Shareholders”). 
  
 R E C I T A L S 
  
 WHEREAS, under the terms of
the private placements completed by Duska Scientific Co. (“Duska”) in April 2004 and August 2004, Duska agreed to register the shares of the Company’s common stock issuable upon exercise of the warrants sold in those financings;

  
 WHEREAS, pursuant to the terms of the Amendment to Agreement
and Plan of Reorganization dated June 30, 2004 by and among the Company, Duska, Shiprock Subsidiary, Inc. (“Sub”) Tommy J. Gropp (“Gropp”) and Michael Artis (“Artis”), the Company agreed to register the shares of the
Company’s common stock owned by Gropp and Artis; and 
  
 WHEREAS, the Company also wishes to register certain of the shares of the Company’s common stock issued to Duska’s shareholders in connection with the merger of Duska with Sub (the “Merger”) and certain of the shares of
the Company’s common stock issuable upon the exercise of the warrants issued to Duska’s warrantholders in connection with the Merger. 
  
 NOW, THEREFORE, in consideration of the foregoing premises and for other good and valuable consideration, the parties hereby agree as follows: 

 
 1. Definitions. 
  
 As used in this Agreement, the following terms have the respective meanings
set forth below: 
  
 Commission: shall mean the Securities
and Exchange Commission or any other federal agency at the time administering the Securities Act. 
  
 Exchange Act: shall mean the Securities Exchange Act of 1934, as amended. 
  
 “Holder” and “Holders” means (i) the Shareholders, (ii) any person holding Registrable
Securities to whom the registration rights under this Agreement have been validly transferred. 
  
 Person: shall mean an individual, partnership, limited liability company, joint stock company, corporation, trust or unincorporated organization, and a government or agency or political subdivision thereof.

  
 Register, Registered and Registration:
shall mean a registration effected by preparing and filing a registration statement in compliance with the Securities Act (and any post-effective 

  

 
amendments filed or required to be filed) and the declaration or ordering of effectiveness of such registration statement. 
  
 Registrable Securities: shall mean (i) those shares of the
Company’s common stock issued to the persons and in the amounts set forth on the signature page hereto, (ii) those shares of the Company’s common stock issuable upon the exercise of the warrants previously issued to the persons and in the
amounts set forth on the signature page hereto, and (iii) any securities of the Company issued as a dividend or other distribution with respect to, or in exchange for or in replacement of, the shares of the Company’s common stock referred to in
(i) or (ii) above; provided, that Registrable Securities shall not include (a) such securities as are eligible for sale pursuant to Rule 144(k) (or any successor provision thereto) under the Securities Act (“Rule 144(k)”), or (b) such
securities as have been registered under the Securities Act and subsequently sold by the Holder. 
  
 Registration Expenses: shall mean all expenses incurred by the Company in compliance with Sections 2(a) and (b) hereof, including, without
limitation, all registration, qualification and filing fees, printing expenses, fees and disbursements of counsel for the Company, blue sky fees and expenses and the expense of any special audits incident to or required by any such registration (but
excluding the compensation of regular employees of the Company, which shall be paid in any event by the Company). 
  
 Securities Act: shall mean the Securities Act of 1933, as amended. 
  
 Selling Expenses: shall mean all underwriting discounts and selling commissions applicable to the Securities
registered by the Holders. 
  
 Warrant Holders: shall mean
the Holders of a majority of the warrants then outstanding (including shares of common stock issued upon exercise of such warrants) that were issued to the investors in the Company’s private placement that was completed in August 2004.

  
 2. Registration Rights 
  
 2.1 Registration. On or prior to October 30, 2004,
the Company shall file a registration statement (the “Registration Statement”) covering all of the Registrable Securities and thereafter shall use its commercially reasonable best efforts to as soon as practicable effect such registration
(including, without limitation, appropriate qualification under applicable state securities laws and appropriate compliance with applicable regulations issued under the Securities Act and any other governmental requirements or regulations).

  
 (a) Underwriting. If requested, the
Company shall, together with all Holders proposing to sell their Registrable Securities in such registration in an underwritten distribution (the “Initiating Holders”), enter into an underwriting agreement in customary form with an
investment banking firm or firms selected for such underwriting by a majority in interest of the Initiating Holders, but subject to the Company’s reasonable approval. The Company may, at its option, include shares held by other securityholders
of the Company in any such registration statement filed under this Section 2.1. Notwithstanding the foregoing, if in the good faith judgment of the managing underwriter of such public offering, the inclusion of all of the Registrable Securities
requested to be registered would materially and adversely affect the 

  

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successful marketing of the offering, then the amount of the securities to be included in the offering shall be reduced and the Registrable Securities and
the other shares to be offered shall participate in such offering as follows: (i) first, the Registrable Securities requested to be included in such registration by the Initiating Holders, and if two or more Initiating Holders are included in the
registration, pro rata among the Initiating Holders on the basis of the number of Registrable Securities owned by each such Initiating Holder, and (ii) second, the shares requested to be included in such registration by any stockholder other than
the Initiating Holders, in any manner determined by the Company (including in any manner specified in any agreement between the Company and such other stockholders). If any Holder of Registrable Securities disapproves of the terms of the
underwriting, such person may elect to withdraw therefrom by written notice to the Company. 
  
 2.2 Expenses of Registration. All Registration Expenses incurred in connection with the registration pursuant to Section 2.1 shall
be borne by the Company, including, but not limited to, printing, legal and accounting expenses, SEC filing fees and “blue sky” fees and expenses; provided, however, that the Company shall have no obligation to pay or otherwise bear (i)
any portion of the fees or disbursements of counsel for the Holders in connection with the registration of their Registrable Securities, (ii) any portion of the underwriter’s commissions or discounts, expense allowance or fees or stock transfer
taxes attributable to the Registrable Securities being offered and sold by the Holders of Registrable Securities, or (iii) any of such expenses if the payment of such expenses by the Company is prohibited by the laws of a state in which such
offering is qualified and only to the extent so prohibited. Unless otherwise stated, all Selling Expenses relating to securities registered on behalf of the Holders shall be borne by the Holders of such securities pro rata on the basis of the number
of shares so registered or proposed to be so registered. 
  
 2.3 Registration Procedures. In the case of the registration effected by the Company pursuant to this Agreement, the Company will keep each Holder advised in writing as to the initiation of such registration
and as to the completion thereof. The Company will: 
  
 (a) Prepare and file with the Commission the Registration Statement and such amendments and supplements as may be necessary and use its commercially reasonable best efforts to cause the Registration Statement to become and remain effective
until (i) the first anniversary following the date the Registration Statement is declared effective, or (ii) all of the Registrable Securities included in the Registration Statement have been sold, whichever comes first, except that the Company
shall be permitted to suspend the use of the Registration Statement during certain periods as set forth below in this Section 2.3; 
  
 (b) Furnish to the Holders participating in such registration and to the underwriters of the securities being registered such reasonable
number of copies of the Registration Statement, preliminary prospectus, final prospectus and such other documents as such underwriters may reasonably request in order to facilitate the public offering of such securities; 
  
 Notwithstanding the foregoing, the Company shall notify each Holder whose
securities are included in the registration of the happening of any event which makes any statement made in the Registration Statement or related prospectus or any document incorporated or deemed to 

  

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be incorporated therein by reference untrue in any material respect or which requires the making of any changes in the Registration Statement or prospectus
so that, in the case of the Registration Statement, it will not contain an untrue statement of a material fact or omit to state a material fact required to be stated therein or necessary to make the statements therein not misleading, and that in the
case of the prospectus, it will not contain an untrue statement of a material fact or omit to state a material fact necessary in order to make the statements therein, in the light of the circumstances under which they were made, not misleading. In
such event, the Company may suspend use of the prospectus on written notice to each participating Holder, in which case each participating Holder shall not dispose of Registrable Securities covered by the Registration Statement or prospectus until
copies of a supplemented or amended prospectus are distributed to the participating Holders or until the participating Holders are advised in writing by the Company that the use of the applicable prospectus may be resumed (the period of such
suspension shall be a “Blackout Period”). The Company shall ensure that the use of the prospectus may be resumed as soon as practicable. The Company shall, upon the occurrence of any event contemplated by this paragraph, prepare a
supplement or post-effective amendment to the Registration Statement or a supplement to the related prospectus or any document incorporated therein by reference or file any other required document so that, as thereafter delivered to the purchasers
of the Registrable Securities being sold thereunder, such prospectus will not contain an untrue statement of a material fact or omit to state a material fact necessary to make the statements therein, in the light of the circumstances under which
they were made, not misleading. In the event that the Company declares one or more Blackout Periods, the one-year anniversary period set forth in Section 2.3(a) shall be extended by the number of days that constitute any such Blackout Periods.

  
 2.4 Indemnification. 
  
 (a) The Company will indemnify each Holder, each of its
officers and directors and partners, and each person controlling such Holder within the meaning of Section 12 of the Securities Act, with respect to which registration has been effected pursuant to this Agreement, against all expenses, claims,
losses, damages and liabilities (or actions in respect thereof), including any of the foregoing incurred in settlement of any litigation, commenced or threatened, arising out of or based on any untrue statement (or alleged untrue statement) of a
material fact contained in the Registration Statement, prospectus, offering circular or other document, or any amendment or supplement thereto, incident to any such registration, or based on any omission (or alleged omission) to state therein a
material fact required to be stated therein or necessary to make the statements therein, in the light of the circumstances under which they were made, not misleading, or any violation by the Company of the Securities Act, the Exchange Act, state
securities laws or any rule or regulation promulgated under such laws applicable to the Company in connection with any such registration, and the Company will reimburse each such Holder, each of its officers and directors, and each person
controlling such Holder, for any legal and any other expenses reasonably incurred, as such expenses are incurred, in connection with investigating, preparing or defending any such claim, loss, damage, liability or action, provided that the Company
will not be liable in any such case to the extent that any such claim, loss, damage, liability or expense arises out of or is based on any untrue statement or omission or alleged untrue statement or omission, made in reliance upon and in conformity
with written information furnished to the Company by or on behalf of such Holder for use therein. 
  

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 (b) Each Holder will, if Registrable Securities held by such Holder are included in the
securities as to which such registration is being effected, indemnify the Company, each of its officers and directors, each person who controls the Company within the meaning of Section 15 of the Securities Act, each other holder of the
Company’s securities covered by the Registration Statement, and each such holder’s officers and directors and each person controlling such holder within the meaning of Section 15 of the Securities Act, against all claims, losses, damages
and liabilities (or actions in respect thereof) arising out of or based on any untrue statement (or alleged untrue statement) of a material fact contained in the Registration Statement, prospectus, offering circular or other document, or any
omission (or alleged omission) to state therein a material fact required to be stated therein or necessary to make the statements therein not misleading, or any violation by the Holder of the Securities Act, the Exchange Act, state securities laws
or any rule or regulation promulgated under such laws applicable to the Holder, and will reimburse the Company, such other holders, such officers, directors, or control persons for any legal or any other expenses reasonably incurred, as such
expenses are incurred, in connection with investigating or defending any such claim, loss, damage, liability or action, but in the case of the Company or the other holders or their officers, directors, or control persons, only to the extent that
such untrue statement (or alleged untrue statement) or omission (or alleged omission) is made in the Registration Statement, prospectus, offering circular or other document in reliance upon and in conformity with information furnished to the Company
in writing by such Holder. Notwithstanding the foregoing, the liability of each Holder under this Section 2.4(b) shall be limited to an amount equal to the net proceeds from the offering received by such Holder. A Holder will not be required to
enter into any agreement or undertaking in connection with any registration under this Section 2 providing for any indemnification or contribution on the part of such Holder greater than the Holder’s obligations under this Section 2.4(b).

  
 (c) Each party entitled to indemnification
under this Section 2.4 (the “Indemnified Party”) shall give notice to the party required to provide indemnification (the “Indemnifying Party”) promptly after such Indemnified Party has actual knowledge of any claim as to which
indemnity may be sought, and shall permit the Indemnifying Party to assume the defense of any such claim or any litigation resulting therefrom, provided that counsel for the Indemnifying Party, who shall conduct the defense of such claim or
litigation, shall be approved by the Indemnified Party (whose approval shall not unreasonably be withheld), and the Indemnified Party may participate in such defense at such party’s expense, and provided further that the failure of any
Indemnified Party to give notice as provided herein shall not relieve the Indemnifying Party of its obligations under this Agreement unless the failure to give such notice is materially prejudicial to an Indemnifying Party’s ability to defend
such action and provided further, that the Indemnifying Party shall not assume the defense for matters as to which there is a conflict of interest or there are separate and different defenses. No Indemnifying Party, in the defense of any such claim
or litigation, shall, except with the consent of each Indemnified Party (whose consent shall not be unreasonably withheld), consent to entry of any judgment or enter into any settlement which does not include as an unconditional term thereof the
giving by the claimant or plaintiff to such Indemnified Party of a release from all liability in respect to such claim or litigation. 
  
 (d) Notwithstanding the foregoing, to the extent that the provisions on indemnification and contribution contained in the underwriting
agreement entered into in 

  

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connection with the underwritten public offering are in conflict with the foregoing provisions, the provisions in the underwriting agreement shall control.

  
 3. Termination of Registration Rights. The registration
rights granted pursuant to Section 2.1 of this Agreement shall terminate upon the first anniversary of the effective date of the Registration Statement; provided, however, that the Company agrees to use its commercially reasonable best efforts to
cause the Registration Statement to remain effective until the third anniversary of the date of this Agreement if it receives a written request to do so from the Warrant Holders prior to the first anniversary date of the Registration Statement.

  
 4. Transfer of Rights. The rights granted under Section
2 of this Agreement may be assigned to any transferee or assignee in connection with any transfer or assignment by the Holder of such Holder’s Warrants or Registrable Securities, provided that: (i) such transfer is otherwise effected in
accordance with applicable securities laws and the terms of this Agreement; (ii) written notice is promptly given to the Company; and (iii) such transferee or assignee agrees in writing to be bound by the provisions of this Agreement and by any
other agreement reasonably necessary to ensure compliance with the Federal and state securities laws. 
  
 5. Lock-Up. In the event the Company seeks to sell shares of its securities in an underwritten public offering, the Company may, at the request of
the underwriter for such offering, impose on each Holder a so-called “lock-up” period in connection with the public offering of not more than twelve months from the effective date of the registration statement for the public offering
covering all of the Holder’s shares of the Company’s common stock. 
  
 6. Miscellaneous. 
  
 6.1 Consent to Jurisdiction. The Company and the Holders (i) hereby irrevocably submit to the exclusive jurisdiction of the United States District Court and the courts of the State of Pennsylvania located in
Philadelphia, Pennsylvania, for the purposes of any suit, action or proceeding arising out of or relating to this Agreement, and (ii) hereby waive, and agree not to assert in any such suit, action or proceeding, any claim that it is not personally
subject to the jurisdiction of such court, that the suit, action or proceeding is brought in an inconvenient forum or that the venue of the suit, action or proceeding is improper. The Company and each Holder consents to process being served in any
such suit, action or proceeding by mailing a copy thereof to such party at the address in effect for notices to it under this Agreement and agrees that such service shall constitute good and sufficient service of process and notice thereof. Nothing
in this Section 6.1 shall affect or limit any right to serve process in any other manner permitted by law. 
  
 6.2 Amendments and Waivers. The provisions of this Agreement, including the provisions of this sentence, may not be amended,
modified or supplemented, and waivers or consents to departures from the provisions hereof may not be given, unless the same shall be in writing and signed by the Company and a majority in interest of the Holders. 
  
 (a) Notices. Any and all notices or other
communications or deliveries required or permitted to be provided hereunder shall be in writing and shall be deemed given and effective on the earlier of (i) the date of transmission, if such notice or communication 

  

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is delivered via facsimile at the facsimile telephone number specified for notice prior to 5:00 p.m., Eastern Standard Time, on a business day, (ii) the
first business day after the date of transmission, if such notice or communication is delivered via facsimile at the facsimile telephone number specified for notice later than 5:00 p.m., Eastern Standard Time, on any date and earlier than 11:59
p.m., Eastern Standard Time, on such date, (iii) the business day following the date of mailing, if sent by nationally recognized overnight courier service, or (iv) actual receipt by the party to whom such notice is required to be given. 

 

	 	(x)	if to the Company: 

  

	 	    	Duska Therapeutics, Inc. 

	 	    	Two Bala Plaza, Suite 300 

	 	    	Bala Cynwyd, PA 19004 

	 	    	Attention: President 

	 	    	Telecopier: (610) 660-0966 

	 	    	Telephone: (610) 660-6690 

  

	 	(y)	if to a Holder, at the Holder’s address set forth in the signature pages to this Agreement 

  
 or to such other address or addresses or facsimile number or numbers as any such party may most recently have designated in writing to the
other parties hereto by such notice. 
  
 6.3
Successors and Assigns. This Agreement shall be binding upon and inure to the benefit of the parties and their successors and permitted assigns. 
  
 6.4 Counterparts. This Agreement may be executed in any number of counterparts, each of which when so executed shall be deemed to
be an original, and all of which taken together shall constitute one and the same Agreement. In the event that any signature is delivered by facsimile transmission, such signature shall create a valid binding obligation of the party executing (or on
whose behalf such signature is executed) the same with the same force and effect as if such facsimile signature were the original thereof. 
  
 6.5 Governing Law. This Agreement shall be governed by and construed in accordance with the laws of the State of Pennsylvania,
without regard to principles of conflicts of law thereof. This Agreement shall not be interpreted or construed with any presumption against the party causing this Agreement to be drafted. 
  
 6.6 Severability. If any term, provision, covenant or
restriction of this Agreement is held to be invalid, illegal, void or unenforceable in any respect, the remainder of the terms, provisions, covenants and restrictions set forth herein shall remain in full force and effect and shall in no way be
affected, impaired or invalidated, and the parties hereto shall use their reasonable efforts to find and employ an alternative means to achieve the same or substantially the same result as that contemplated by such term, provision, covenant or
restriction. It is hereby stipulated and declared to be the intention of the parties that they would have executed the remaining terms, provisions, covenants and restrictions without including any of such that may be hereafter declared invalid,
illegal, void or unenforceable. 
  

 - 7 - 

 6.7 Headings. The headings herein are for convenience only, do not constitute a
part of this Agreement and shall not be deemed to limit or affect any of the provisions hereof. 
  
 IN WITNESS WHEREOF, the undersigned have executed this Agreement as of the date first set forth above. 
  

			
	DUSKA THERAPEUTICS, INC.
		
	 By:
	 	 
		
	 Name:
	 	 
		
	 Title:
	 	 

  

	
	SHAREHOLDERS:
	
	  
	(Signature)
	
	  
	(Signature)

  
 Common stock shares to be registered:

  
 Warrant shares to be registered:  
  

 - 8 -

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