Document:

EXHIBIT 10.1a

 

Farley White Wiggins, LLC

c/o Farley White Interests

155 Federal Street, Suite 1200

Boston, MA 02110

 

February 1, 2007

 

Anika Therapeutics, Inc.

160 New Boston Street

Woburn, MA 01801

Attention: Charles H. Sherwood

 

		Re:	Lease dated January 3, 2007 between Farley White Wiggins, LLC as Landlord and Anika Therapeutics, Inc. as Tenant with respect
to the building known and numbered as 32 Wiggins Avenue, Bedford, MA (the “Lease”)

 

Dear Mr. Sherwood:

 

This letter will confirm our understanding and agreement that, in order to correct a
scrivener’s error, the phrase “From the sixth (6th) anniversary” in the fourth paragraph of the definition
of Annual Base Rent in Article 1.1 of the Lease is deleted and replaced with the phrase “From the fifth (5th)
anniversary”.

 

Please indicate your agreement with the foregoing by signing and returning a counterpart
copy of this letter, which shall constitute an amendment to the Lease. It is agreed that electronic signatures shall constitute
originals for all purposes.

 

Thank you for your attention to this matter.

 

Sincerely,

 

Farley White Wiggins, LLC

 

 

	By: 	/s/ Roger W. Altreuter	 	 
	 	Roger W. Altreuter	 	 
	 	Manager	 	 
	 	Hereunto duly authorized	 	 
	 	 	 
	Agreed to as aforesaid:	 	 
	 	 	 
	Anika Therapeutics, Inc.	 	 
	 	 	 
	 	 	 
	By: 	/s/ Charles H. Sherwood	 	 
	 	Charles Sherwood	 	 
	 	CEO	 	 
	 	Hereunto duly authorizedEXHIBIT 10.3a

 

AMENDMENT 

TO THE LEASE CONTRACT OF A FUTURE BUILDING 

 

between

 

CONSORZIO ZONA INDUSTRIALE E PORTO FLUVIALE DI PADOVA, (hereinafter
the “Landlord”), represented by the president and legal representative pro tempore, Luca Deiana, Esq.,
with corporate office in Padua, Galleria Spagna no. 35, Tax Code: 80007410287, pursuant to the powers evidenced under Annex “I”,

 

- on one side –

 

and

 

ANIKA THERAPEUTICS S.r.l., (hereinafter even only the “Tenant”)
represented by the president and the legal representative pro tempore, Charles H. Sherwood, Ph.D., with corporate office
in Via Ponte della Fabbrica 3/B, 35031 Abano Terme, Italy, Tax Code: 01510440744, pursuant to the powers hereto attached as Annex
“II”,

 

- on the other side –

 

Whereas:

 

		A.	On October 9, 2015, the Landlord and the Tenant entered into (i) a lease contract of a future building
with non-residential purposes (the “Contract”) and (ii) a sale contract of future goods (the “Sale
Agreement”).

	B.	During the course of the Construction Works of the Building, the Tenant required the Landlord to
make the changes to the Executive Project as listed and described in Annex “III” attached hereto (the “Changes”).
	C.	The Landlord accepted
the Changes.

		D.	As a consequence of the Changes the Parties agree that the Contract as well as the Sale Agreement
have to be amended pursuant to the terms and conditions provided herein.

 

In light of the above,

 

it is agreed as follows.

 

 

Article 1 - Recitals, Annexes and
Definitions

 

The recitals and the annexes to this amendment agreement (the “Amendment
Agreement”) are an integral and substantial part of this Amendment Agreement.

 

Annexes to the Amendment Agreement are the followings:

 

- Annex “I”:Powers of the Landlord

 

- Annex “II”:Powers of the Tenant

 

     

     

    

 

- Annex “III”:List of Changes

 

All the terms defined in the Contract are used herein with the same
meaning, except as specifically modified by this Amendment Agreement.

 

 

Article 2 - Undertaking to execute the Changes

 

		2.1	The Landlord undertakes to execute, on a workmanlike basis, the Construction Works of the Building
on the basis of the Executive Project as amended by, and/or pursuant to, the Changes. Tenant has duly approved the Changes and
signifies its approval by executing this Amendment Agreement.

 

 

Article 3 - Postponement of the
Construction Works Term

 

		3.1	The Landlord undertakes to complete the physical construction of the Building by the effective
date of this Amendment Agreement (the “Physical Construction Completion Date”). From the Physical Construction
Completion Date, the Landlord agrees and guarantees that the Tenant shall have free and unencumbered access to the Building to
execute the Fit-Out Works.

		3.2	The Landlord confirms that by and no later than the Physical Construction Completion Date, as described
under Section 3.1 above, the ownership of the Goods (as defined in the Sale Agreement) shall be transferred by the Landlord to
the Tenant, which will receive them.

		3.3	The Construction Works Term shall be postponed to February 25, 2017 provided that the provisions
of article 7 of the Contract shall remain in full force and effect among the Parties. As a result, the language in art. 5.1 of
the Contract shall be deleted in its entirety and replaced with the following: “The Landlord undertakes to complete all necessary
activities required by the Lease Agreement or the Amendment Agreement (including the Construction Works of the Building on the
basis of the Executive Project as amended by, and/or pursuant to, the Changes) to be completed during the Construction Works Term
(as defined below) by February 25, 2017 (the “Construction Works Term”), except (i) as provided for under art.
7.3 of the Contract or art. 8 of the Contract, as amended in this Amendment Agreement; (ii) any additional postponement agreed
in writing by the Parties; or (iii) delays due to force majeure.” The Parties agree that the explicit purpose of this Amendment
Agreement is to agree and ascertain that the Delivery Date, as defined in the Contract, occurs no later than February 28, 2017.

		3.4	Should the Landlord be in breach of the obligation under clause 3.3 above, the penalty under Article
8 of the Contract, without giving effect to the grace period described therein (it being understood that any grace period is deleted
by this Amendment Agreement), shall apply, meaning that any delay by Landlord of any of the activities required to be completed
by the Construction Works Term (i.e. February 25, 2017) shall result in the immediate imposition of the penalties to Landlord described
therein. Notwithstanding the foregoing, Tenant agrees that the penalty described herein and in the Contract shall not be applied
to Landlord’s failure to complete the “collaudo tecnico amministrativo” portion of the Testing Procedure described
in the Contract within the Construction Works Term (as required) provided that any prospective failure by Landlord in this regard
does not alter the exterior aspect of the Building and does not prevent the entire, easy and complete use of the Building in the
manner provided by the Contract and this Amendment Agreement.

 

     

     

    

Article 4 – Additional costs

 

	4.1	The Changes are to be deemed as Discretional Variations pursuant to the Contract and, therefore,
the directly consequential costs (the “Additional Costs”) shall be borne by the Tenant.
	4.2	The Parties agree that
the overall Additional Costs are equal to Euro 318.446,16 plus VAT.
	4.3	The Additional Cost shall be paid in a lump sum by the Tenant to the Landlord on the basis of a
special invoice to be issued by Landlord to Tenant within five (5) days of the Delivery Date.
	 	 

 

Article 5 - Parties Domicile

 

		5.1	For any notice related to the Contract, the Sale Agreement and this Amendment Agreement, the Tenant changes its domicile as
follow:

 

		·	ANIKA THERAPEUTICS s.r.l.,

For times prior to March 1, 2017:

Via Ponte della Fabbrica 3/B

35031 Abano Terme, Italy

After March 1, 2017:

Corso Stati Uniti 4

35127 Padova, Italy

Sylvia Cheung

scheung@anikatherapeutics.com;

Dana Alexander

DAlexander@AnikaTherapeutics.com

With copy to Arturo Meglio

 arturo.meglio@klgates.com

 

 

     

     

    

Article 6 – Venue

 

For any dispute that may arise between the Parties in connection
with the existence, content and interpretation of this Amendment Agreement, the Court of Padua shall be exclusively competent.

 

 

Article 7 - Miscellaneous

 

		7.1	Any provision of the Contract and any provision of the Sale Agreement not expressly amended by
this Amendment Agreement shall remain in full force and effect among the Parties, provided that the Contract and the Sale Agreement
shall be construed in accordance with this Amendment Agreement.

		7.2	This Amendment Agreement is executed in a bilingual version, in Italian and in English, it being
understood between the Parties that for the interpretation purposes of this Amendment Agreement or of any other deed deriving from
the same, the Italian version shall prevail.

 

 

	2 Febbraio 2017	 	 
	 	 	 
	CONSORZIO ZONA INDUSTRIALE E	 	ANIKA THERAPEUTICS s.r.l.
	PORTO FLUVIALE DI PADOVA	 	 
	 	 	 
	/s/ Luca Deiana	 	/s/ Charles H.
Sherwood

 

 

 

 

 

     

     

    

 

Annex “I”:       Powers of the Landlord

 

 

 

 

 

 

 

 

 

     

     

    

 

Annex “II”:       Powers
of the Tenant

 

 

 

 

 

 

 

 

 

     

     

    

 

Annex “III”:       List of ChangesEXHIBIT 10.6a

 

EXHIBIT A

 

TOLLING AGREEMENT AMENDMENT

 

Between

 

FIDIA FARMACEUTICI S.P.A. with registered office
in Abano Terme (PD), via Ponte della Fabbrica 3/A, Italy, V.A.T. No. 00204260285 (hereinafter “Fidia”)

 

And

 

Anika Therapeutics S.r.l. with
registered office in Abano Terme (PD), via Ponte della Fabbrica 3/B, Italy, V.A.T. No. 03641500289 (hereinafter “Anika
Srl”)

 

(hereinafter jointly referred to as the “Parties”
and each one as a “Party”)

 

WHEREAS

 

	A.	On December 30, 2009 Fidia and Anika Srl (formerly Fidia Advanced Biopolymers S.r.l.) entered into a Tolling Agreement
(the “Tolling Agreement”);
	 	 
	B.	The Parties have discussed and negotiated certain amendments to the Tolling Agreement and reached
an agreement as to such amendments.

 

	C.	The Parties intend to formalize the amendments they agreed upon to the Tolling Agreement in this
Tolling Agreement Amendment (the “Amendment Agreement”).

 

NOW, THEREFORE, for good and valuable consideration, the
receipt and sufficiency of which is hereby acknowledged, the Parties hereby agree as follows:

 

		1.	Definition included in the Tolling Agreement shall have the same meaning in this Amendment Agreement.

 

		2.	As of the date of this Amendment Agreement, Annex A, Annex C, Annex E and
Annex H to the Agreement are replaced by the revised Annex A, Annex C, Annex E and Annex H attached to this Agreement.

 

		3.	The provision ““FOB” has the meaning ascribed to it in
INCOTERMS (2010 version);” is hereby deleted from Section 1.1.

 

		4.	The following provision is hereby inserted, in alphabetical order, in Section 1.1:

 

““EX
WORKS” has the meaning ascribed to it in INCOTERMS (2010 version)”

 

““Product
Family” means a grouping of Products that share the same Intermediate (ACP or each HYAFF grade) as well as the Intermediate
itself where sold as bulk.”

 

     

     

    

 

		5.	Section 4.1 of the Agreement is hereby amended as follows:

“For
the period up to 30 June 2010, the non-binding forecast attached as Annex I shall apply. For the calendar year 2012 (January to
December), and for each consecutive twelve (12) month period thereafter, Customer shall provide Manufacturer with a written twelve
(12) month forecast of its estimated orders for Product and/or Intermediates, if any (each a “Forecast”). Each Forecast
shall be delivered to Manufacturer at least one hundred and twenty (120) days prior to the beginning of the applicable twelve (12)
month period. Said Forecast is a non-binding estimate and shall not obligate Customer to purchase the volume of Product and/or
Intermediates set forth in it; provided, however, that eighty percent (80%) of aggregate volume forecasted within each Product
Family forecasted in such Forecast shall be purchased by Customer and Customer shall deliver Orders to Manufacturer pursuant to
clauses 4.4 and 4.5 (each, an “Order”) during such twelve (12) month period for quantities of Product and/or Intermediates
which, in the aggregate for each Product Family, amount to at least the binding portion of such Forecast. A Product Family consists
of products sharing a common Intermediate (ACP or same grade of HYAFF (Hyaff 11p75 - Hyaff 11 p75HE TBA - Hyaff 11 pl00 BA - Hyaff
11pl00 TBA).

 

For 2011, the forecast submitted
by Customer to Manufacturer on April 29, 2011 was the official forecast for that year, and eighty percent (80%) of the aggregate
volume forecasted shall be binding upon Customer. Customer shall deliver Orders to Manufacturer pursuant to clauses 4.3 and 4.4
(each, an “Order”) during such twelve (12) month period for quantities of Product and/or Intermediates which, in the
aggregate, amount to at least the binding portion of such forecast.

 

On the last day
of each quarter (31 December, 31 March, 30 June, 30 September) during a calendar year, the Customer will submit an updated 12-
month rolling forecast of which the first three (3) months shall be binding and the other nine (9) months shall be for information
purpose only and not binding in nature”.

 

		6.	Section 4.9.1 of the Agreement is hereby amended as follows:

“Subject
to clause 4.2 and 4.3, Manufacturer shall deliver 100% of the Product and/or Intermediates set forth in an Order with a range of
tolerance equal to +/- 10% within five days following, or one day prior to, the date specified on the applicable Order. In cases
where the Manufacture is unable to deliver 100% of an order within thirty (30) days after the specified delivery date, the Customer
can request rework or repackaging of an equivalent product into the configuration ordered, at the Manufacturer's expense. For other
cases, should the Manufacturer more than once during rolling twelve (12) month period fail to provide any quantity of the Product
and/or Intermediates ordered with an Order placed for forecasted quantity and not cure such default within ninety (90) days after
the date of such failure, then the Customer reserves the right to take any or all of the following actions:

 

    	2

     

    

 

		a)	arrange for direct expedited routing of the Product and/or Intermediates
(with the entire cost of such expedited routing to be borne by Manufacturer); or

		b)	terminate the Order upon Notice to Manufacturer and purchase substitute Product
and/or Intermediate from another supplier. Such Product and/or Intermediate purchased from another supplier shall count towards
the total quantity with respect to the binding forecast requirements of clause 4.1.

 

		7.	Section 5.1 of the Agreement is hereby amended as follows:

“The customer
has two facilities; one in Abano Terme, Italy and the other in Bedford, Massachusetts, USA. Delivery to Customer's Abano Terme
warehouse in Abano Terme, Italy and delivery to the Customer's Bedford warehouse shall be EX WORKS Manufacturer facility in Abano
Terme, Italy, unless otherwise agreed by the Parties. All Product and /or Intermediate shall be properly packed, marked and delivered
by Manufacturer in accordance with the Specifications an instructions included in the Order in a format previously agreed upon
by the Parties”.

 

		8.	Section 9.1 of the Agreement is hereby amended as follows:

“The risk
of loss in connection with the Products and/or Intermediates shall pass to the Customer upon delivery in accordance with Section
5.1”.

 

		9.	Section 10.1 of the Agreement is hereby amended as follows:

“Title
to the Products and/or Intermediates will pass upon delivery to the Customer in accordance with Section 5.l”.

 

Except as set forth above, the Tolling
Agreement shall remain in full force and effect in accordance with its terms.

 

IN WITNESS WHEREOF, the parties have executed
or caused this Tolling Agreement Amendment to be executed.

 

 

Effective January 1, 2012

 

 

	FIDIA FARMACEUTICI S.P.A.	 	 
	 	 	 
	By: 	/s/ Antonio Germani	 	 
	 	 	 
	ANIKA THERAPEUTICS S.R.L.	 	 
	 	 	 
	By: 	/s/ Charles H. Sherwood	 	 

 

 

 

 

3

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