Document:

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                                                                   EXHIBIT 10.15

                        SEPARATION AGREEMENT AND RELEASE

                  This Separation Agreement and Release (the "Agreement") is
entered into as of July 25, 2003, by Stefanie Sovak (the "Employee") and IPC
Acquisition Corp., a Delaware corporation (the "Company") (collectively, the
"Parties"), in consideration of the respective agreements and promises of the
Parties contained in this Agreement. The Parties acknowledge that the terms and
conditions of this Agreement have been voluntarily agreed to and are intended to
be final and binding.

                  1. Resignation; Transition Services.

                           (a) The Employee agrees and confirms that, effective
as of July 21, 2003, she voluntarily resigned from her position as Senior Vice
President, Business Development and Product Management, of the Company and from
all other positions she then held as an officer and director of the Company and
its subsidiaries and affiliates. The Employee acknowledges and agrees that, from
and after July 21, 2003, she will no longer be authorized to incur any expenses,
obligations or liabilities on behalf of the Company.

                           (b) The Employee agrees that, during the Transition
Period (as hereinafter defined), the Employee shall be employed by the Company
in a non-officer capacity, to assist the Company, at such times and in such a
manner as shall be reasonably requested by the Chief Executive Officer of the
Company (the "CEO") or his designee, in (i) transitioning her duties and
responsibilities to one or more individuals identified by the CEO and (ii) such
other special projects as determined by the CEO or his designee. The Employee's
services pursuant to this Section 1 shall be required to be performed only
during normal business hours. The Employee and the Company hereby agree that the
Employee's employment with the Company and its subsidiaries and affiliates shall
cease on the Termination Date (as defined below). For purposes of this
Agreement, the "Transition Period" shall mean that period commencing upon July
22, 2003 and ending upon the earlier of (i) April 26, 2004 and (ii) such other
date determined in accordance with Section 7 hereof (the earlier of April 26,
2004 and such earlier date, the "Termination Date").

                  2. Base Compensation.

                           (a) During the Transition Period the Employee shall
be paid a base salary as follows: (i) in respect of the period beginning on the
date hereof and ending on September 30, 2003 the Employee shall continue to be
paid her base salary at an annual rate of $190,000 and (ii) in respect of the
period beginning on October 1, 2003 and ending on April 26, 2004 the Employee
will be paid a base salary at an annual rate of $100,000.

                           (b) During the Transition Period, the Employee shall
continue to participate in all employee benefit plans in which she currently
participates at the same levels as in effect on July 21, 2003 and shall be
eligible for the Company match, if any, under its 401(k) plan for the year
ending September 30, 2003; provided, however, that, from and after July 21,
2003, the Employee shall not (i) accrue any vacation days, (ii) be paid in
respect of any currently accrued and unused vacation days or (iii) receive any
incentive compensation (cash or equity) from the Company or any of its
affiliates. During the Transition Period, the Company shall

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reimburse the Employee for any actual out-of pocket business expenses incurred
in the performances of her duties hereunder, provided that (a) such expenses
were approved by the Company prior to being incurred and (b) the Employee
submits to the Company reasonably detailed receipts in accordance with the
Company's general policy on expense reimbursement.

                  3. Administrative Support. During the Transition Period, the
Company shall make available to the Employee the use of her current
administrative assistant, Linda Leone, or Ms. Leone's successor, to answer
telephone calls on behalf of the Employee and to provide other administrative
support reasonably requested by the Employee, in each case as currently provided
to the Employee; provided, however, that the use of such assistant for such
other administrative support shall not exceed 4 hours per week. During the
Transition Period, the Company will maintain the Employee's current office
telephone number, voicemail account and voice-mail access. The Employee shall be
responsible for providing herself with any necessary office space during the
Transition Period at her own expense.

                  4. Other Payments. In connection with the Employee's
resignation and in consideration of the Employee's covenants herein, the
Employee shall be entitled to the following payments and benefits so long as (i)
she has executed and not revoked this Agreement and the Initial Release (as
hereinafter defined) contained in Section 5 hereof and (ii) she is at the time
of such payment not in violation of any non-competition agreement she has
entered into with the Company:

                           (a) within twenty days following the execution by the
Executive of the Initial Release, the Employee shall be paid by the Company a
lump-sum cash payment in the amount of $100,000; and

                           (b) the Company shall provide the Employee with up to
3 months of outplacement services with an outplacement/recruiting firm mutually
agreed by the Company and the Employee, at the Company's cost.

                           (c) In the event the Employee's employment with the
Company terminates in accordance with Section 7 hereof, and so long as the
Employee has executed and not revoked the Final Release (as hereinafter defined)
in accordance with Section 6 hereof:

                                    (A) within twenty days following the
execution by the Employee of the Final Release, the Company shall pay the
Employee a lump sum cash payment in the amount equal to the base salary that she
would have been paid in respect of the period commencing on the Termination Date
and ending on April 26, 2004 had she continued her employment through April 26,
2004; and

                                    (B) if the Employee elects "continuation
coverage" for medical or dental benefits pursuant to Section 4980B of the
Internal Revenue Code of 1986, as amended, and Part 6 of Title I of the Employee
Retirement Income Security Act of 1974, as amended ("ERISA"), the Employee's
premium payment for such coverage shall, for the period commencing on the
Termination Date and ending on April 26, 2004, be equal to the rates for such
coverages paid by the Employee immediately prior to the Termination Date.

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                  5. Initial Release of Claims by the Employee.

                           (a) In consideration of the Company's covenants and
the payments and benefits provided for hereunder, the sufficiency of which the
Employee acknowledges, the Employee, with the intention of binding herself and
her heirs, executors, administrators and assigns, does hereby release, remise,
acquit and forever discharge the Company and each of its subsidiaries and
affiliates (the "Company Affiliated Group"), their present and former officers,
directors, executives, agents, attorneys and employees, and the successors,
predecessors and assigns of each of the foregoing (collectively, the "Company
Released Parties"), of and from any and all claims, actions, causes of action,
complaints, charges, demands, rights, damages, debts, sums of money, accounts,
financial obligations, suits, expenses, attorneys' fees and liabilities of
whatever kind or nature in law, equity or otherwise, whether accrued, absolute,
contingent, unliquidated or otherwise and whether now known or unknown,
suspected or unsuspected, which the Employee, individually or as a member of a
class, now has, owns or holds, or has at any time heretofore had, owned or held,
against any Company Released Party in any capacity, including, without
limitation, any and all claims (i) arising out of or in any way connected with
the Employee's service to any member of the Company Affiliated Group (or the
predecessors thereof) in any capacity, or the termination of such service in any
such capacity, (ii) for severance or vacation benefits, unpaid wages, salary
(other than in respect of the current pay-cycle) or incentive payments, (iii)
for breach of contract, wrongful discharge, impairment of economic opportunity,
defamation, intentional infliction of emotional harm or other tort, (iv) for any
violation of applicable state and local labor and employment laws (including,
without limitation, all laws concerning unlawful and unfair labor and employment
practices) and (v) for employment discrimination under any applicable federal,
state or local statute, provision, order or regulation, and including, without
limitation, any claim under Title VII of the Civil Rights Act of 1964 ("Title
VII"), the Fair Labor Standards Act, the Americans with Disabilities Act
("ADA"), ERISA, the Age Discrimination in Employment Act and any similar or
analogous state statute, excepting only the rights of the Employee: (A) under
this Agreement; (B) under the Non-Qualified Stock Option Agreement entered into
between the Parties, dated as of April 5, 2002 and the Non-Qualified Stock
Option Agreement entered into between the Parties, dated as of April 25, 2003
(collectively, the "Stock Options"); (C) under the Key Employee Stock Purchase
Agreement between the Parties, dated as of July 25, 2002 and related Secured
Promissory Note and Security Agreement (the "Key Employee Stock Purchase
Agreement"); (D) to indemnification, if any, under the applicable corporate law,
the by-laws or certificate of incorporation of the Company, or as an insured
under any director's and officer's liability insurance policy now or previously
in force; (E) under any "pension plan" (within the meaning of Section 3(2) of
ERISA), and (F) for reimbursement of unreimbursed business expenses incurred
prior to the July 21, 2003. For purposes of this Agreement, the foregoing
release shall be referred to as (the "Initial Release").

                           (b) The Employee acknowledges and agrees that the
release of claims set forth in this Initial Release is not to be construed in
any way as an admission of any liability whatsoever by any Company Released
Party, any such liability being expressly denied.

                           (c) The release of claims set forth in this Initial
Release applies to any relief no matter how called, including, without
limitation, wages, back pay, front pay,

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compensatory damages, liquidated damages, punitive damages, damages for pain or
suffering, costs, and attorney's fees and expenses.

                           (d) The Employee specifically acknowledges that her
acceptance of the terms of the release of claims set forth in this Initial
Release is, among other things, a specific waiver of her rights, claims and
causes of action under the Age Discrimination in Employment Act, Title VII, ADA
and any state or local law or regulation in respect of discrimination of any
kind; provided, however, that nothing herein shall be deemed, nor does anything
contained herein purport, to be a waiver of any right or claim or cause of
action which by law the Employee is not permitted to waive.

                           (e) Other than as to rights, claims and causes of
action arising under the Age Discrimination in Employment Act, the release of
claims set forth in this Initial Release shall be immediately effective upon
execution by the Employee.

                           (f) As to rights, claims and causes of action arising
under the Age Discrimination in Employment Act the Employee shall have a period
of 21 days to consider whether to execute this Agreement. If the Employee
accepts the terms hereof and executes this Agreement, she may thereafter, for a
period of 7 days following (and not including) the date of execution, revoke
this Agreement as it relates to claims arising under the Age Discrimination in
Employment Act. If no such revocation occurs, this Agreement shall become
irrevocable in its entirety, and binding and enforceable against the Employee,
on the day next following the day on which the foregoing seven-day period has
elapsed.

                           (g) The Employee acknowledges and agrees that she has
not, with respect to any transaction or state of facts existing prior to the
date hereof, filed any complaints, charges or lawsuits against any Company
Released Party with any governmental agency, court or tribunal.

                  6. Final Release; Exercisability of Options. As a condition
precedent to the Employee receiving the payments and benefits set forth in
Section 4(b) above, the Employee shall, at the close of business on the
Termination Date, execute the general release attached hereto as Exhibit A (the
"Final Release"). Notwithstanding anything to the contrary contained in this or
any other Agreement, in the event the Employee fails to execute the Final
Release or executes but revokes the Final Release, the Stock Options shall
automatically terminate.

                  7. Early Termination. In the event the Employee becomes
employed by, or otherwise provides services in any capacity to, any entity or
business other than the Company [that unreasonably interferes with the
Employee's duties hereunder], the Transition Period and the Employee's
employment with the Company shall immediately terminate. The Employee shall
inform the Company of any employment or services provided to any entity or
business other than the Company prior to the Termination Date and shall provide
the Company with such information relating thereto as it shall reasonably
request.

                  8. Return of Company Property. The Employee agrees that she
has returned, or promptly after the date hereof shall return, to the Company all
documents, files, and other property of any kind belonging to the Company (and
all copies thereof); provided, however, that

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the Employee may keep the Company-provided laptop computer (the "Computer")
currently in her possession; provided, further, however, that the Employee shall
deliver the Computer to the Company within 5 days following the date hereof in
order for the Company to remove all Company-related information from it, after
which time the Computer shall be returned to the Employee.

                  9. Employee References. In the event that the Company is asked
to provide a reference on the Employee's behalf prior to the end of the
Transition Period, the Company shall confirm that the Employee is an employee of
the Company in good standing. In the event that the Company is asked to provide
a reference on the Employee's behalf following the Transition Period, the
Company shall confirm (a) the Employee's dates of employment, (b) the Employee's
date of resignation as an officer and her Termination Date and (c) that the
Employee was an employee in good standing during the entirety of her employment
with the Company.

                  10. Notices. Any notice required or desired to be delivered
hereunder shall be in writing and shall be delivered personally, by courier
service, by certified mail, return receipt requested, or by fax, and shall be
effective when actually delivered to the Party to whom such notice shall be
directed, and shall be addressed as follows (or to such other address as the
Party entitled to notice shall hereafter designate in accordance with the terms
hereof):

                                   If to the Company:
                                   IPC Acquisition Corp.
                                   88 Pine Street, Wall Street Plaza
                                   New York, NY 10005
                                   Attention:  John McSherry. Esq.
                                   Fax:  (212) 344-5106

                                   If to the Employee:
                                   Stefanie Sovak
                                   154 Hudson Street
                                   Cornwall-on-Hudson, NY 12520
                                   Fax: ___________________

                  11. Legal Fees. The Company shall reimburse the Employee in an
amount not to exceed $2,500 for her legal fees incurred in connection with the
negotiation and review of this Agreement.

                  12. Withholding. The Company shall have the right to deduct
from any amount payable under this Agreement any taxes or other amounts required
by applicable law to be withheld.

                  13. Complete Agreement. This Agreement constitutes the
complete agreement of the Parties and shall supersede all agreements between the
Parties to the extent they relate in any way to the employment, termination of
employment, compensation and employee

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benefits of the Employee, other than the Stock Options and the Key Employee
Stock Purchase Agreement.

                  14. Counterparts. This Agreement may be executed in several
counterparts, each of which shall be deemed to be an original, but all of which
together shall constitute one and the same instrument.

                  15. Successors. This Agreement shall be binding upon any and
all successors and assigns of the Employee and the Company.

                  16. Governing Law. Except for issues or matters as to which
federal law is applicable, this Agreement shall be governed by and construed and
enforced in accordance with the laws of the State of New York without giving
effect to the conflicts of law principles thereof.

                            [signature page follows]

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                  IN WITNESS WHEREOF, this Agreement has been signed by or on
behalf of each of the Parties, all as of the date first above written.

                                        IPC Acquisition Corp.

/s/  STEFANIE SOVAK                     /s/ JOHN MCSHERRY
-------------------------------         -------------------------------
Stefanie Sovak                          By: John McSherry
                                        Its: General Counsel, Secretary

Dated:  July 25, 2003                   Dated:  July 25, 2003
        -----------------------                 -----------------------

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                                 GENERAL RELEASE

1. General Release.

         In consideration of the payments to be made and benefits provided to
Stefanie Sovak (the "Employee") as set forth in the Separation Agreement and
Release entered into between the IPC Acquisition Corp. (the "Company"), dated as
of July 25, 2003 (the "Separation Agreement"), the Employee with the intention
of binding herself and her heirs, executors, administrators and assigns, does
hereby release, remise, acquit and forever discharge the Company and each of its
subsidiaries and affiliates (the "Company Affiliated Group"), their present and
former officers, directors, executives, agents, attorneys and employees, and the
successors, predecessors and assigns of each of the foregoing (collectively, the
"Company Released Parties"), of and from any and all claims, actions, causes of
action, complaints, charges, demands, rights, damages, debts, sums of money,
accounts, financial obligations, suits, expenses, attorneys' fees and
liabilities of whatever kind or nature in law, equity or otherwise, whether
accrued, absolute, contingent, unliquidated or otherwise and whether now known
or unknown, suspected or unsuspected, which the Employee, individually or as a
member of a class, now has, owns or holds, or has at any time heretofore had,
owned or held, against any Company Released Party in any capacity, including,
without limitation, any and all claims (i) arising out of or in any way
connected with the Employee's service to any member of the Company Affiliated
Group (or the predecessors thereof) in any capacity, or the termination of such
service in any such capacity, (ii) for severance or vacation benefits, unpaid
wages, salary or incentive payments, (iii) for breach of contract, wrongful
discharge, impairment of economic opportunity, defamation, intentional
infliction of emotional harm or other tort, (iv) for any violation of applicable
state and local labor and employment laws (including, without limitation, all
laws concerning unlawful and unfair labor and employment practices) and (v) for
employment discrimination under any applicable federal, state or local statute,
provision, order or regulation, and including, without limitation, any claim
under Title VII of the Civil Rights Act of 1964 ("Title VII"), the Fair Labor
Standards Act, the Americans with Disabilities Act ("ADA"), the Employee
Retirement Income Security Act of 1974, as amended ("ERISA"), the Age
Discrimination in Employment Act ("ADEA") and any similar or analogous state or
local statute, excepting only the rights of the Employee: (A) under the
Separation Agreement, (B) under the Non-Qualified Stock Option Agreement entered
into between the Parties, dated as of April 5, 2002 and the Non-Qualified Stock
Option Agreement entered into between the Parties, dated as of April 25, 2003;
(C) under the Key Employee Stock Purchase Agreement between the Parties, dated
as of July 25, 2002 and related Secured Promissory Note and Security Agreement;
(D) to indemnification, if any, under the applicable corporate law, the by-laws
or certificate of incorporation of the Company, or as an insured under any
director's and officer's liability insurance policy now or previously in force;
(E) under any "pension plan" (within the meaning of Section 3(2) of ERISA), and
(F) for claims for reimbursement of unreimbursed business expenses incurred
prior to the date hereof pursuant to Section 2(b) of the Separation Agreement.

2. No Admissions. The Employee acknowledges and agrees that this General Release
is not to be construed in any way as an admission of any liability whatsoever by
any Company Released Party, any such liability being expressly denied.

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3. Application to All Forms of Relief. This General Release applies to any
relief no matter how called, including, without limitation, wages, back pay,
front pay, compensatory damages, liquidated damages, punitive damages, damages
for pain or suffering, costs, and attorney's fees and expenses.

4. Specific Waiver. The Employee specifically acknowledges that her acceptance
of the terms of this General Release is, among other things, a specific waiver
of her rights, claims and causes of action under Title VII, Age Discrimination
in Employment Act, ADA and any state or local law or regulation in respect of
discrimination of any kind; provided, however, that nothing herein shall be
deemed, nor does anything contained herein purport, to be a waiver of any right
or claim or cause of action which by law the Employee is not permitted to waive.

5. Revocation. The Employee shall have a period of 21 days following the
Termination Date to consider whether to execute this General Release. If the
Employee accepts the terms hereof and executes this General Release prior to the
expiration of such 21-day period, she may thereafter, for a period of 7 days
following (and not including) the date of execution, revoke this General
Release. If no such revocation occurs, this General Release shall become
irrevocable in its entirety, and binding and enforceable against the Employee,
on the day next following the day on which the foregoing seven-day period has
elapsed. This General Release shall be void if executed earlier than the close
of business on the Termination Date.

6. No Complaints or Other Claims. The Employee acknowledges and agrees that she
has not, with respect to any transaction or state of facts existing prior to the
date hereof, filed any complaints, charges or lawsuits against any Company
Released Party with any governmental agency, court or tribunal.

7. Governing Law. Except for issues or matters as to which federal law is
applicable, this General Release shall be governed by and construed and enforced
in accordance with the laws of the State of New York without giving effect to
the conflicts of law principles thereof.

IN WITNESS WHEREOF, this General Release has been signed by or on behalf of each
of the parties, all as of the date first above written.

                                        IPC Acquisition Corp.

/s/  STEFANIE SOVAK                     /s/ JOHN MCSHERRY
-------------------------------         -------------------------------
Stefanie Sovak                          By: John McSherry
                                        Its: General Counsel, Secretary

Dated:  July 25, 2003                   Dated:  July 25, 2003
        -----------------------                 -----------------------

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                                                                    EXHIBIT 10.1

                    AMENDED AND RESTATED EMPLOYMENT AGREEMENT

         AGREEMENT dated as of the 24th day of October, 2002 between Barr
Laboratories, Inc., a New York corporation having its principal executive
offices at 300 Corporate Drive, Building #10, Bradley Corporate Park, Blauvelt,
New York 10913 (the "Company"), and Bruce L. Downey (the "Employee").

                                   WITNESSETH:

         WHEREAS, the Company and the Employee entered into an employment
agreement dated as of January 4, 1993, which was amended and restated as of
August 8, 2002 (as so amended and restated, the "Employment Agreement"); and

         WHEREAS, the Company and the Employee wish to further amend and restate
the Employment Agreement;

         NOW, THEREFORE, the Company and the Employee hereby agree that,
effective as of October 24, 2002, the Employment Agreement is amended and
restated in its entirety to read as follows:

         1.       Employment. The Company agrees to employ the Employee, and the
Employee agrees to remain in the employ of the Company, during the term of this
Agreement and on the other terms and conditions hereafter set forth.

         2.       Term. The term of this Agreement shall commence on August 8,
2002 (the "Commencement Date") and shall terminate at the close of business on
the third anniversary of the Commencement Date unless sooner terminated in
accordance with the terms of this Agreement or extended as hereinafter provided.
The term of this Agreement shall be extended, without further action by the
Company or the Employee, on the second anniversary of the Commencement Date (the
"Extension Effective Date") and on each subsequent anniversary of the
Commencement Date (each also an "Extension Effective Date"), for successive
periods of twelve months each, unless either party shall have given written
notice to the other party, in the manner set forth in paragraph 13(e) or (f)
below, prior to the Extension Effective Date in question, that the term of this
Agreement that is in effect at the time such written notice is given is not to
be extended or further extended, as the case may be. Examples that illustrate
the intended operation of the preceding sentence appear in the Appendix to this
Agreement.

         3.       Positions and Responsibilities; Place of Performance.

                  (a)      Throughout the term of this Agreement, the Employee
agrees to remain in the employ of the Company, and the Company agrees to employ
the Employee, as the Chief Executive Officer of the Company, reporting only to
the Board of Directors of the Company (the "Board"). As the Chief Executive
Officer of the Company, the Employee shall be the most senior officer of the
Company and its subsidiaries, shall have effective supervision, control and
policy-making authority over, and responsibility for,

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the strategic direction and general leadership and management of the business
and affairs of the Company and its subsidiaries, subject only to the authority
of the Board, and shall have all of the powers, authority, duties and
responsibilities he has had prior to the Commencement Date and all of the
powers, authority, duties and responsibilities usually incident to the position
and role of Chief Executive Officer in public companies that are comparable in
size, character and performance to the Company. All employees of the Company and
its subsidiaries shall report, directly or indirectly, to the Employee. The
Company agrees to use its best efforts to secure the Employee's election as a
member and Chairman of the Board during the term of this Agreement, and the
Employee agrees to serve as such without additional compensation beyond that
provided in this Agreement.

                  (b)      In connection with his employment by the Company, the
Employee shall be based at a location of his choosing in the greater Washington,
D.C. metropolitan area or at any other Company location, as he may determine to
be appropriate for the performance of his duties, and he agrees to travel, to
the extent reasonably necessary to perform his duties and obligations under this
Agreement, to Company facilities and other destinations elsewhere at the
Company's expense.

                  (c)      During the term of this Agreement, the Employee shall
serve the Company on an exclusive basis and shall devote all his business time,
attention, skill and efforts to the faithful performance of his duties
hereunder; provided that the Employee may engage in community service and
charitable activities and, with the approval of the Board, may serve as a member
of the board of directors of other companies (and retain remuneration for such
service) if such activities and service do not materially interfere with the
performance of his duties and responsibilities hereunder.

         4.       Compensation. For all services rendered by the Employee in any
capacity during the term of this Agreement, and for his undertakings with
respect to confidential information, non-solicitation and disparaging remarks
set forth in sections 6 and 7 below, the Employee shall be entitled to the
following:

                  (a)      a salary, payable in installments not less frequent
than monthly, at the annual rate of eight hundred and fifty thousand dollars
($850,000), with such increases in such rate, if any, as the Compensation
Committee of the Board may approve from time to time during the term of this
Agreement (the annual salary rate as increased from time to time during the term
of this Agreement being hereafter referred to as the "Base Salary");

                  (b)      participation in the Company's annual executive
incentive or bonus plan as in effect from time to time, with the opportunity to
receive an award in accordance with the terms and conditions of such plan, for
each fiscal year of the Company that commences or terminates during the term of
this Agreement, of up to 50% of the Base Salary earned during such year (or such
higher percentage as the Board or a committee of the Board may allow from time
to time during the term of this Agreement), it being understood that any award
for the fiscal year of the Company in which the term of this Agreement
terminates pursuant to the terms hereof shall be prorated based on the

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portion of such fiscal year that coincides with the term of this Agreement and
shall be made at the same time as awards (if any) are made to other participants
with respect to such fiscal year. The Employee recognizes and agrees that the
Board may defer the payment of any portion of his annual bonus to the extent
that, and for such period of time as, may be reasonably necessary to avoid a
loss of the Company's tax deduction with respect to such portion of his annual
bonus under section 162(m) of the Internal Revenue Code. Any such deferred
amount shall be non-forfeitable, shall constitute an unfunded, unsecured
obligation of the Company, and until paid shall be deemed invested in such
hypothetical investments as the Employee may select from among the hypothetical
investment options that are available from time to time during the deferral
period under the Company's excess 401(k) plan or, if no such investment options
are available at the time in question under that plan, then from among the same
hypothetical investment options that are available under such plan on the date
of this Agreement or a reasonable facsimile thereof;

                  (c)      participation in the Company's stock incentive plan
as from time to time in effect, subject to the terms and conditions of such
plan;

                  (d)      the business and personal use of an automobile at
Company expense including, without limitation, payment or reimbursement of
automobile insurance and maintenance expenses in accordance with the Company's
automobile policy applicable to senior officers on the Commencement Date; and

                  (e)      participation in all Company health, welfare, savings
and other employee benefit and fringe benefit plans (including vacation pay
plans or policies and life and disability insurance plans) in which other senior
officers of the Company participate during the term of this Agreement, subject
in all events to the terms and conditions of such plans as in effect from time
to time. Nothing in this paragraph (e) shall preclude the Company from amending
or terminating any such plan at any time. The plans covered by this paragraph
(e) shall not include the annual incentive or stock incentive plans, which are
covered by paragraphs (b) and (c) above.

         5.       Termination of Employment.

                  (a)      Termination by the Company without Good Cause or by
the Employee for Good Reason.

                           (i)      If the Employee's employment with the
Company is terminated by the Company without Good Cause or is terminated by the
Employee for Good Reason during the term of this Agreement and other than at or
after the expiration of the term of this Agreement as the same may have been
extended in accordance with the provisions of section 2 above (any such
employment termination being hereafter referred to as a "Compensable
Termination"), the Company shall pay the Employee the portion of his Base Salary
accrued through the date of the Compensable Termination and any other amounts to
which he is entitled by law or pursuant to the terms of any compensation or
benefit plan or arrangement in which he participated prior to the

                                  page 3 of 20

<PAGE>

Compensable Termination and, in addition, subject to compliance by the Employee
with the provisions of sections 6 and 7 below, relating to confidential
information, non-solicitation and disparaging remarks, the Company shall, as
liquidated damages or severance pay or both (whichever characterization(s) will
serve to validate the payments), and as additional consideration for the
Employee's undertakings under sections 6 and 7 below, pay the Employee the
following:

                                    (A)      his annual bonus for the fiscal
year of the Company preceding the fiscal year of the Company in which the
Compensable Termination occurs, if unpaid at the time of the Compensable
Termination, the amount of such bonus to be determined by the Compensation
Committee of the Board on a basis consistent with its prior bonus determinations
with respect to the Employee or, in the event a Change in Control or Potential
Change in Control (as defined in section 11 below) occurred before the
Compensable Termination, consistent with its bonus determinations with respect
to the Employee prior to the Change in Control or Potential Change in Control;

                                    (B)      a prorated annual bonus for the
fiscal year of the Company in which the Compensable Termination occurs, such
prorated annual bonus to be determined by multiplying the "Applicable Average
Bonus" as defined below in this subparagraph 5(a)(i)(B) by a fraction the
numerator of which shall be the number of days elapsed in such fiscal year
through (and including) the date on which the Compensable Termination occurs and
the denominator of which shall be the number 365. For purposes of this
Agreement, the "Applicable Average Bonus" means the higher of (I) the average
annual bonus (including any deferred bonus) awarded to the Employee during the
three year period immediately preceding the Compensable Termination, or (II) the
average annual bonus (including any deferred bonus) awarded to the Employee
during the three fiscal years of the Company preceding the fiscal year in which
the Compensable Termination occurs; provided that, if the Compensable
Termination occurs after a Change in Control or Potential Change in Control, the
Applicable Average Bonus shall not be less than the average annual bonus
(including any deferred bonus) awarded to the Employee during the three years
preceding the date on which the Change in Control or Potential Change in Control
occurred; and

                                    (C)      an amount of money (the "Severance
Payment") equal to three (3) times the Employee's "Annual Cash Compensation" as
hereafter defined, unless the Employee attained age 65 but not age 70 (or such
later age or ages as the Board may in its discretion determine) prior to the
Compensable Termination, in which case the Severance Payment shall be equal to
two (2) times such Annual Cash Compensation, or unless the Employee attained age
70 (or such later age as the Board may in its discretion determine) prior to the
Compensable Termination, in which case the Severance Payment shall be equal to
one (1) times such Annual Cash Compensation. Except as otherwise provided
hereafter in this subparagraph 5(a)(i)(C), the Severance Payment shall be paid
as follows: fifty percent (50%) of the Severance Payment (or, if the Employee
attained age 65 but not age 70 (or such later age or ages as the Board may in
its discretion determine) prior to the Compensable Termination, seventy-five
percent (75%) of the Severance Payment, or if the Employee attained age 70 prior
to the

                                  page 4 of 20

<PAGE>

Compensable Termination, one hundred percent (100%) of the Severance Payment)
shall be paid in a lump sum within ten days after the date of the Compensable
Termination. Any balance of the Severance Payment shall be paid in eighteen (18)
equal monthly installments one of which shall be paid at the end of each of the
first eighteen (18) months after the date of the Compensable Termination,
provided, in the case of each of the final 12 of such 18 installments, that the
Employee has not accepted full-time or regular part-time employment with or
regularly served as a consultant to a for-profit pharmaceutical company prior to
the date for payment of such installment, it being understood and agreed that
the foregoing condition shall not be violated by the Employee's serving as a
member of a board of directors of a for-profit pharmaceutical company or by his
performing consulting services on an ad hoc basis for such a company. However,
if the Employee attained age 65 (or such later age as the Board may in its
discretion determine) prior to the date of the Compensable Termination, then any
balance of the Severance Payment shall be paid in six equal monthly installments
one of which shall be paid at the end of each of the first six months after the
date of the Compensable Termination, and the preceding sentence shall not apply.
If a Change in Control or Potential Change in Control as defined in section 11
below occurs (either before or after the Compensable Termination), the Severance
Payment (or, in the case of a Change in Control or Potential Change in Control
that occurs after the Compensable Termination, any portion thereof that remains
unpaid at the time such Change in Control or Potential Change in Control occurs)
shall be paid in a lump sum within ten days after the Compensable Termination
(or, in the case of a Change in Control or Potential Change in Control that
occurs after the Compensable Termination, within ten days after the Change in
Control or Potential Change in Control occurs), and the two preceding sentences
of this subparagraph shall not apply. During the 18 month period following a
Compensable Termination, the Company shall also provide the Employee with COBRA
coverage at its expense. For purposes of this section 5, the Employee's "Annual
Cash Compensation" shall mean the sum of (I) the Employee's highest Base Salary
(i.e., one year's salary at its highest rate), plus (II) the "Applicable Average
Bonus" as defined in subparagraph 5(a)(i)(B) above.

                           (ii)     If the term of this Agreement as the same
may have been extended in accordance with the provisions of section 2 above is
not extended or further extended because the Company gives written notice of
non-extension to the Employee as provided in section 2 above, and the Company
does not have Good Cause for termination of the Employee's employment at the
time of giving such notice, and the Employee does not thereafter resign for Good
Reason during the term of this Agreement as permitted by paragraph 5(d)(v)
below, then the Company, subject to fulfillment by the Employee of his
obligations under this Agreement during the balance of the term and his
compliance with the provisions of sections 6 and 7 below, relating to
confidential information, non-solicitation and disparaging remarks, shall, as
non-renewal compensation, and as additional consideration for the Employee's
undertakings under this Agreement including sections 6 and 7 below, pay the
Employee an amount of money (the "Non-Renewal Payment") equal to two (2) times
the Employee's Annual Cash Compensation as defined in subparagraph 5(a)(i)(C)
above (unless the Employee has attained age 70 (or such later age as the Board
may in its discretion determine) prior to the termination date, in which

                                  page 5 of 20

<PAGE>

case the Non-Renewal Payment shall be equal to one (1) times the Employee's
Annual Cash Compensation), in addition to any other amounts to which the
Employee may be entitled hereunder (including without limitation his annual
bonus pursuant to paragraph 4(b) above for the fiscal year of the Company in
which his employment terminates and any amounts to which he may be entitled
under section 8, 9 or 10 below) or by law or pursuant to the terms of any
compensation or benefit plan or arrangement in which he participated before his
employment terminated. Except as otherwise provided hereafter in this
subparagraph 5(a)(ii), the Non-Renewal Payment shall be paid as follows:
seventy-five percent (75%) of the Non-Renewal Payment, or if the Employee
attained age 70 prior to the termination of his employment, one hundred percent
(100%) of the Non-Renewal Payment, shall be paid in a lump sum within ten days
after the date on which the Employee's employment terminates. Any balance of the
Non-Renewal Payment shall be paid in six (6) equal monthly installments one of
which shall be paid at the end of each of the first six months after the date on
which the Employee's employment terminates. If a Change in Control or Potential
Change in Control as defined in section 11 below occurs (either before or after
the termination of his employment), the Non-Renewal Payment (or, in the case of
a Change in Control or Potential Change in Control that occurs after the
employment termination, any portion thereof that remains unpaid at the time such
Change in Control or Potential Change in Control occurs) shall be paid in a lump
sum within ten days after the employment termination (or, in the case of a
Change in Control or Potential Change in Control that occurs after the
employment termination, within ten days after the Change in Control or Potential
Change in Control occurs). During the 18 month period following the termination
of his employment, the Company shall also provide the Employee with COBRA
coverage at its expense.

                           (iii)    The foregoing provisions of (including any
payments under) this paragraph 5(a) shall be in lieu of any severance pay that
may be payable under any plan or practice of the Company, but shall be in
addition to (and not in lieu of) any payments to which the Employee may be
entitled under sections 8, 9 and 10 below. Subparagraphs 5(a)(i)(C) and 5(a)(ii)
above are intended to be mutually exclusive, and in no event shall such
subparagraphs, either individually or collectively, be construed to require the
Company to pay an amount of money in excess of three (3) times the Employee's
Annual Cash Compensation under such subparagraphs, either individually or
collectively, in addition to the 18 months of COBRA coverage provided for
therein. The Employee shall not be required to mitigate the amount of any
payment or benefit provided for in this Agreement (including but not limited to
any payment provided for above in this paragraph 5(a)) by seeking other
employment or otherwise, nor shall any compensation earned by the Employee in
other employment or otherwise reduce the amount of any payment or benefit
provided for in this Agreement.

                  (b)      Termination by the Company for Good Cause or by the
Employee without Good Reason. If, during the term of this Agreement, the
Employee's employment by the Company is terminated by the Company for Good Cause
or by the Employee without Good Reason, the Employee shall not be entitled to
receive any compensation under section 4 above accruing after the date of such
termination or any

                                  page 6 of 20

<PAGE>

payment under paragraph 5(a) above. However, the Company's obligations under
sections 8, 9 and 10 shall not be affected by such termination of employment.
The provisions of this paragraph 5(b) shall be in addition to, and not in lieu
of, any other rights and remedies the Company may have at law or in equity or
under any other provision of this Agreement in respect of such termination of
employment. However, if during the term of this Agreement the Employee's
employment is terminated by the Employee without Good Reason and the Employee
gives the Company at least 120 days' advance notice of such termination, then
the Employee shall not have any obligation or liability to the Company under
this Agreement in respect of such termination of employment, but his obligations
under Section 6 and 7 hereof shall not be affected by such termination of
employment.

                  (c)      Good Cause Defined. For purposes of this Agreement,
the Company shall have "Good Cause" to terminate the Employee's employment
during the term of this Agreement only if:

                           (i)      the Employee fails to substantially perform
his duties hereunder for any reason or fails to devote substantially all his
business time exclusively to the affairs of the Company or fails to obtain the
consent of the Board to his service on the board of directors of another
company, and such failure is not discontinued within a reasonable period of
time, in no event to exceed 30 days, after the Employee receives written notice
from the Company of such failure; or

                           (ii)     the Employee commits an act of dishonesty
resulting or intended to result directly or indirectly in gain or personal
enrichment at the expense of the Company; or

                           (iii)    the Employee is grossly negligent or engages
in willful misconduct or insubordination in the performance of his duties
hereunder; or

                           (iv)     the Employee materially breaches his
obligations under section 6 or paragraph 7(a) below, relating to confidential
information and non-solicitation.

Any foregoing provision of this paragraph 5(c) to the contrary notwithstanding,
the Company shall not have "Good Cause" to terminate the Employee's employment
within three years after a Change in Control or Potential Change in Control (as
such terms are defined in section 11 below) unless (A) the Employee's act or
omission is willful and has a material adverse effect upon the Company, (B) the
Board of Directors gives the Employee (I) written notice warning of its
intention to terminate the Employee for Good Cause if the specified act or
omission alleged to constitute Good Cause is not discontinued and, if curable,
cured, and (II) a reasonable opportunity after receipt of such written notice,
but in no event less than two weeks, to discontinue and, if curable, cure the
conduct alleged to constitute Good Cause, and (C) the Employee fails to
discontinue and, if curable, cure the act or omission in question; provided that
clauses (B) and (C) of this sentence shall not apply with respect to misconduct
on the part of the Employee that

                                  page 7 of 20

<PAGE>

constitutes a felony in the jurisdiction in which the Employee engages in such
misconduct, and, provided further, that this sentence shall not apply to conduct
involving moral turpitude. For all purposes of this Agreement, no act, or
failure to act, on the Employee's part shall be deemed "willful" unless done, or
omitted to be done, by him intentionally and in bad faith (i.e., without
reasonable belief that his action or omission was in furtherance of the
interests of the Company or a subsidiary of the Company).

                  (d)      Good Reason Defined. For purposes of this Agreement,
the Employee shall have "Good Reason" to terminate his employment during the
term of this Agreement only if:

                           (i)      the Company fails to pay or provide any
amount or benefit that the Company is obligated to pay or provide under section
4 above or section 8, 9 or 10 below and the failure is not remedied within 30
days after the Company receives written notice from the Employee of such
failure; or

                           (ii)     the Company assigns the Employee duties,
responsibilities or reporting relationships not contemplated by section 3 above
without his consent, or limits his duties or responsibilities or power or
authority contemplated by section 3 above in any respect materially detrimental
to him, and in either case the situation is not remedied within 30 days after
the Company receives written notice from the Employee of the situation; or

                           (iii)    he is removed from, or not elected or
reelected to, the Board of Directors of the Company or the office, title and
position of Chairman of the Board and Chief Executive Officer of the Company,
and the Company does not have Good Cause for doing so; or

                           (iv)     the Company relocates his office outside of
either (A) the greater Washington, D.C. metropolitan area, or (B) such other
Company location as he may determine to be appropriate for the performance of
his duties, in either case (A) or (B) without his written consent (given in a
personal rather than representative capacity), and the situation is not remedied
within 30 days after the Company receives written notice from the Employee of
the situation; or

                           (v)      the Company gives the Employee written
notice, in the manner set forth in paragraph 13(e) or (f) below, prior to any
Extension Effective Date, that the term of this Agreement that is in effect at
the time such written notice is given is not to be extended or further extended,
as the case may be; provided that the giving of such written notice to the
Employee shall constitute Good Reason only if and when the Employee shall have
performed such of his duties and responsibilities for such period of time, in no
event to exceed six months after the giving of such notice, as the Board may
reasonably request in writing to transition his duties and responsibilities; or

                           (vi)     a Change in Control occurs and as a result
thereof either (A) equity securities of the Company cease to be publicly-traded,
or (B) the Employee is

                                  page 8 of 20

<PAGE>

not elected or designated to serve as the sole Chief Executive Officer of the
surviving company; or

                           (vii)    a Change in Control or Potential Change in
Control occurs and (A) the dollar value of the stock optioned to the Employee
annually thereafter is less than the average annual dollar value of the stock
that was optioned to the Employee during the four years prior to the Change in
Control or Potential Change in Control, or (B) the material terms of such
options (including without limitation vesting schedules) are less favorable to
the Employee than the material terms of the options that were granted to the
Employee during the four years prior to the Change in Control or Potential
Change in Control, and in either case (A) or (B) the situation is not remedied
within 30 days after the Company receives written notice from the Employee of
the situation.

In no event shall the Employee's continued employment after any of the foregoing
constitute his consent to the act or omission in question, or a waiver of his
right to terminate his employment for Good Reason hereunder on account of such
act or omission.

         6.       Confidential Information. The Employee agrees not to disclose,
either while in the Company's employ or at any time thereafter, to any person
not employed by the Company, or not engaged to render services to the Company,
except with the prior written consent of an authorized officer of the Company or
as necessary or appropriate for the performance of his duties hereunder, any
confidential information obtained by him while in the employ of the Company,
including, without limitation, information relating to any of the inventions,
processes, formulae, plans, devices, compilations of information, research,
methods of distribution, suppliers, customers, client relationships, marketing
strategies or trade secrets of the Company or any subsidiary thereof; provided,
however, that this provision shall not preclude the Employee from use or
disclosure of information known generally to the public or of information not
considered confidential by persons engaged in the businesses conducted by the
Company or any subsidiary thereof, or from disclosure required by law or court
order. The Employee also agrees that upon leaving the Company's employ he will
not take with him, without the prior written consent of an authorized officer of
the Company, and he will surrender to the Company, any record, list, drawing,
blueprint, specification or other document or property of the Company or any
subsidiary thereof, together with any copy or reproduction thereof, mechanical
or otherwise, which is of a confidential nature relating to the Company or any
subsidiary thereof, or without limitation, relating to its or their methods of
distribution, suppliers, customers, client relationships, marketing strategies
or any description of any formulae or secret processes, or which was obtained by
him or entrusted to him during the course of his employment with the Company.

                                  page 9 of 20

<PAGE>

         7.       Restrictive Covenants

                  (a)      Non-Solicitation. Employee covenants and agrees that,
during his employment by the Company and during the one year period immediately
following the termination of his employment with the Company for any reason
(including, without limitation, a termination of employment by the Company
without cause and a voluntary termination of employment by the Employee, in
either case whether during the term of this Agreement, at the expiration of the
term of this Agreement or at any time thereafter), he will not solicit or
attempt to persuade any employee of the Company, its subsidiaries or affiliates
(except the Employee's personal secretary or administrative assistant), or any
other person who performs services for the Company, its subsidiaries or
affiliates at the time the Employee's employment terminates or at any time
within one year thereafter, to terminate or reduce or refrain from engaging in
his or her employment or other service relationship with the Company, its
subsidiaries or affiliates; provided, however, that responding to inquiries from
any such employees or other persons that are not initiated by the Employee, and
subsequently hiring such employees or other persons following the termination of
their employment with the Company, its subsidiaries and affiliates shall be
permitted.

                  (b)      Specific Enforcement. Employee recognizes and agrees
that, by reason of his knowledge, experience, skill and abilities, his services
are extraordinary and unique, that the breach or attempted breach of any of the
restrictions set forth above in this section 7 will result in immediate and
irreparable injury for which the Company will not have an adequate remedy at
law, and that the Company shall be entitled to a decree of specific performance
of those restrictions and to a temporary and permanent injunction enjoining the
breach thereof, and to seek any and all other remedies to which the Company may
be entitled, including, without limitation, monetary damages, without posting
bond or furnishing security of any kind.

                  (c)      Restrictions Reasonable. Employee specifically and
expressly represents and warrants that (i) he has reviewed and agreed to the
restrictive covenants contained in this section 7 and their contemplated
operation after receiving the advice of counsel of his choosing; (ii) he
believes, after receiving such advice, that the restrictive covenants and their
contemplated operation are fair and reasonable; (iii) he will not seek or
attempt to seek to have the restrictive covenants declared invalid, and, after
receiving the advice of counsel, expressly waives any right to do so; and (iv)
if the full breadth of any restrictive covenant and/or its contemplated
operation shall be held in any fashion to be too broad, such covenant or its
contemplated operation, as the case may be, shall be interpreted in a manner as
broadly in favor of the beneficiary of such covenant as is legally permissible.
Employee recognizes and agrees that the restrictions on his activities contained
in this section 7 are required for the reasonable protection of the Company and
its investments; and that the restriction on his activities set forth in
paragraph 7(a) will not deprive the Employee of the ability to earn a
livelihood.

                  (d)      Non-Disparagement. Employee covenants and agrees
that, during the one year period immediately following the termination of his
employment with the Company for any reason (including, without limitation, a
termination of employment by

                                 page 10 of 20

<PAGE>

the Company without cause and a voluntary termination of employment by the
Employee, in either case whether during the term of this Agreement, at the
expiration of the term of this Agreement or at any time thereafter), he will not
make disparaging remarks about the Company, its subsidiaries or affiliates or
any of their officers, directors or employees, unless required by law or
reasonably necessary to assert or defend his position in a bona fide dispute
arising out of or relating to this Agreement or the breach thereof.

                  (e)      Effect on Termination Payments. The Employee
recognizes and agrees that the Company shall not be obligated to make any
payments provided for in paragraph 5(a) above if the Employee violates the
provisions of section 6 or paragraph 7(a) or 7(d) above during the one year
period immediately following the termination for any reason of his employment
with the Company. In addition, the Employee recognizes and agrees that, if the
Employee violates such provisions, the Company may recoup any payments the
Company may have theretofore made pursuant to paragraph 5(a) above and any
payments the Company may thereafter make under paragraph 5(a). The foregoing
provisions of this paragraph 7(e) shall be in addition to and not by way of
limitation of any other rights and remedies the Company may have in respect of
the violation in question.

         8.       Indemnification

         To the fullest extent permitted by applicable law, the Company shall
indemnify, defend and hold harmless the Employee from and against any and all
claims, demands, actions, causes of action, liabilities, losses, judgments,
fines, costs and expenses (including reasonable attorneys' fees and settlement
expenses) arising from or relating to his service or status as an officer,
director, employee, agent or representative of the Company or any subsidiary of
the Company or in any other capacity in which the Employee serves or has served
at the request of, or for the benefit of, the Company or its subsidiaries. The
Company's obligations under this section 8 shall be in addition to, and not in
derogation of, any other rights the Employee may have against the Company to
indemnification or advancement of expenses, whether by statute, contract or
otherwise.

         9.       Certain Additional Payments by the Company

                  (a)      Anything in this Agreement (other than the second
sentence of this paragraph 9(a)) to the contrary notwithstanding, in the event
it shall be determined that any payment or distribution by the Company to or for
the benefit of the Employee (whether paid or payable or distributed or
distributable pursuant to the terms of this Agreement or otherwise, but
determined without regard to any additional payments required under this section
9) (a "Payment"), would be subject to the excise tax imposed by Section 4999 of
the United States Internal Revenue Code (the "Code") or any interest or
penalties are incurred by the Employee with respect to such excise tax (such
excise tax, together with any such interest and penalties, are hereinafter
collectively referred to as the "Excise Tax"), then the Employee shall be
entitled to receive an additional payment (an "Gross-Up Payment") in an amount
such that after payment by the

                                 page 11 of 20

<PAGE>

Employee of all taxes and any benefits that result from the deductibility by the
Employee of such taxes (including, in each case, any interest or penalties
imposed with respect to such taxes), including, without limitation, any income
taxes (and any interest and penalties imposed with respect thereto) and Excise
Tax imposed upon the Gross-Up Payment, the Employee retains an amount of the
Gross-Up Payment equal to the Excise Tax imposed upon the Payments. However, if
it shall be determined that none of the Payments would be subject to the Excise
Tax if the total Payments were reduced in the aggregate by $50,000 or less, then
in that event the total Payments shall be reduced by the smallest amount (in no
event to exceed $50,000 in the aggregate) necessary to ensure that none of the
Payments will be subject to the Excise Tax. The decision as to which Payments
shall be so reduced shall be made by the Employee.

                  (b)      Subject to the provisions of paragraph 9(a) above and
9(c) below, all determinations required to be made under this section 9,
including whether and when a Gross-Up Payment is required and the amount of such
Gross-Up Payment and the assumptions to be utilized in arriving at such
determination, and whether Payments are to be reduced pursuant to the second
sentence of paragraph 9(a) above, shall be made by Deloitte & Touche or such
other certified public accounting firm as may be designated by the Employee (the
"Accounting Firm") which shall provide detailed supporting calculations both to
the Company and the Employee within 15 business days of the receipt of notice
from the Employee that there has been a Payment, or such earlier time as is
requested by the Company. In the event that the Accounting Firm is serving as
accountant or auditor for the individual, entity or group effecting the "change
in ownership or effective control" or "change in the ownership of a substantial
portion of assets" (within the meaning of Code section 280G(b)(2)(A)) that gives
rise to the Excise Tax, the Employee shall appoint another nationally recognized
accounting firm to make the determinations required hereunder (which accounting
firm shall then be referred to as the Accounting Firm hereunder). All fees and
expenses of the Accounting Firm shall be borne solely by the Company. Any
Gross-Up Payment, as determined pursuant to this section 9, shall be paid by the
Company to the Employee within five days of the receipt of the Accounting Firm's
determination. Any determination by the Accounting Firm shall be binding upon
the Company and the Employee. As a result of the uncertainty in the application
of Section 4999 of the Code at the time of the initial determination by the
Accounting Firm hereunder, it is possible that Gross-Up Payments which will not
have been made by the Company should have been made (an "Underpayment"),
consistent with the calculations required to be made hereunder. In the event
that the Company exhausts its remedies pursuant to paragraph 9(c) and the
Employee thereafter is required to make a payment of any Excise Tax, the
Accounting Firm shall determine the amount of the Underpayment that has occurred
and any such Underpayment, along with any penalty and interest imposed with
respect to such Underpayment, shall be promptly paid by the Company to or for
the benefit of the Employee.

                  (c)      The Employee shall notify the Company in writing of
any claim by the Internal Revenue Service that, if successful, would require
either the payment by the Company of the Gross-Up Payment or the reduction of
Payments pursuant to the second sentence of paragraph 9(a) above. Such
notification shall be given as soon as practicable

                                 page 12 of 20

<PAGE>

but no later than ten business days after the Employee is informed in writing of
such claim and shall apprise the Company of the nature of such claim and the
date on which such claim is requested to be paid. The Employee shall not pay
such claim prior to the expiration of the 30-day period following the date on
which it gives such notice to the Company (or such shorter period ending on the
date that any payment of taxes with respect to such claim is due). If the
Company notifies the Employee in writing prior to the expiration of such period
that it desires to contest such claim, the Employee shall:

                           (i)      give the Company any information reasonably
requested by the Company relating to such claim,

                           (ii)     take such action in connection with
contesting such claim as the Company shall reasonably request in writing from
time to time, including, without limitation, accepting legal representation with
respect to such claim by an attorney reasonably selected by the Company,

                           (iii)    cooperate with the Company in good faith in
order effectively to contest such claim, and

                           (iv)     permit the Company to participate in any
proceedings relating to such claim;

provided, however, that the Company shall bear and pay directly all costs and
expenses (including additional interest and penalties) incurred in connection
with such contest and shall indemnify and hold the Employee harmless, on an
after-tax basis, for any Excise Tax or income tax (including interest and
penalties with respect thereto) imposed as a result of such representation and
payment of costs and expenses. Without limitation on the foregoing provisions of
this paragraph 9(c), the Company shall control all proceedings taken in
connection with such contest and, at its sole option, may pursue or forgo any
and all administrative appeals, proceedings, hearings and conferences with the
taxing authority in respect of such claim and may, at its sole option, either
direct the Employee to pay the tax claimed and sue for a refund or contest the
claim in any permissible manner, and the Employee agrees to prosecute such
contest to a determination before any administrative tribunal, in a court of
initial jurisdiction and in one or more appellate courts, as the Company shall
determine, provided, however, that if the Company directs the Employee to pay
such claim and sue for a refund, the Company shall, if permissible under Section
402 of the Sarbanes-Oxley Act of 2002, advance the amount of such payment to the
Employee on an interest-free basis or, if such an advance is not permissible
thereunder, pay the amount of such payment to the Employee as additional
compensation, and shall indemnify and hold the Employee harmless, on an
after-tax basis, from any Excise Tax or income tax (including interest or
penalties with respect thereto) imposed with respect to such advance or
additional compensation; and further provided that any extension of the statute
of limitations relating to payment of taxes for the taxable year of the Employee
with respect to which such contested amount is claimed to be due is limited
solely to such contested amount. Furthermore, the Company's control of the
contest shall be limited to issues with respect to which a Gross-

                                 page 13 of 20

<PAGE>

Up Payment would be payable hereunder and the Employee shall be entitled to
settle or contest, as the case may be, any other issue raised by the Internal
Revenue Service or any other taxing authority.

                  (d)      If, after the receipt by the Employee of an amount
advanced or paid by the Company pursuant to paragraph 9(a) or 9(c), the Employee
becomes entitled to receive any refund with respect to such claim, the Employee
shall (subject to the Company's complying with the requirements of paragraph
9(c)) promptly pay to the Company the amount of such refund (together with any
interest paid or credited thereon after taxes applicable thereto). If, after the
receipt by the Employee of an amount advanced by the Company pursuant to
paragraph 9(c), a determination is made that the Employee shall not be entitled
to any refund with respect to such claim and the Company does not notify the
Employee in writing of its intent to contest such denial of refund prior to the
expiration of 30 days after such determination, then such advance shall be
forgiven and shall not be required to be repaid and the amount of such advance
shall offset, to the extent thereof, the amount of Gross-Up Payment required to
be paid.

         10.      Certain Enforcement Matters

                  (a)      If, after a Change in Control or Potential Change in
Control, a dispute arises (i) with respect to this Agreement or the breach
thereof, or (ii) with respect to the Employee's or the Company's rights or
obligations under this Agreement, including but not limited to any such dispute
between the Employee and the Company, the Company shall pay or reimburse the
Employee for all reasonable costs and expenses (including court costs,
arbitrators' fees and reasonable attorneys' fees and disbursements) the Employee
incurs in connection with such dispute, including without limitation costs and
expenses he incurs to obtain payment or otherwise enforce his rights under this
Agreement, or to obtain payment of costs and expenses due under this paragraph
10(a). In addition, the Company shall pay the Employee such additional amount (a
"Gross Up") as will be sufficient, after the Employee pays his tax liability
with respect to the Gross Up from the Gross Up, to pay all of his federal, state
and local tax liability with respect to any costs and expenses that are paid by
the Company pursuant to this paragraph 10(a). The Company shall promptly pay or
reimburse the Employee for all such costs and expenses as he incurs them, upon
presentation of reasonable documentation of such costs and expenses, and shall
promptly pay the related Gross Up as and when it pays or reimburses costs and
expenses. The Employee shall not be obligated to repay any such costs, expenses
or Gross Up unless it is finally determined by the trier of fact in a
non-appealable judicial or arbitral decision or ruling (as applicable) that the
Employee's principal positions with respect to the principal matter(s) in
dispute were unreasonable and pursued in bad faith.

                  (b)      Any payments to which the Employee may be entitled
under this Agreement, including, without limitation, under section 5, 8, 9 or 10
hereof, shall be made forthwith on the applicable date(s) for payment specified
in this Agreement. If for any reason the amount of any payment due to the
Employee cannot be finally determined on that date, such amount shall be
estimated on a good faith basis by the Company and

                                 page 14 of 20

<PAGE>

the estimated amount shall be paid no later than within 10 days after such date.
As soon as practicable thereafter, the final determination of the amount due
shall be made and any adjustment requiring a payment to or from the Employee
shall be made as promptly as practicable.

                  (c)      Any controversy or claim arising, after a Change in
Control or Potential Change in Control, out of or related to this Agreement or
the breach thereof, shall be settled by binding arbitration in the City of New
York, in accordance with the employment dispute arbitration rules of the
American Arbitration Association then in effect, and the arbitrator's decision
shall be binding and final and judgment upon the award rendered may be entered
in any court having jurisdiction thereof, except that the Employee may elect to
have any such controversy or claim settled by judicial determination in lieu of
arbitration by bringing a court action, if he is the plaintiff or, if he is not
the plaintiff, demanding such judicial determination within the time to answer
any complaint in any arbitration action that may be commenced.

         11.      Change in Control

                  (a)      The term "Change in Control" as used in this
Agreement means a change of control of a nature that would be required to be
reported in response to Item 6(e) of Schedule 14A of Regulation 14A promulgated
under the Securities Exchange Act of 1934, as amended (the "Exchange Act"),
whether or not the Company is then subject to such reporting requirement;
provided that, whether or not any of the following events would constitute a
change of control of such a nature, a Change in Control shall be deemed to occur
for purposes of this Agreement if and when any of the following events occur:

                           (i)      any "person" (as such term is used in
Sections 13(d) and 14(d)(2) of the Exchange Act), other than--

                                    (A) the Company,

                                    (B) a Subsidiary,

                                    (C) a trustee or other fiduciary holding
                           securities under an employee benefit plan of the
                           Company or a Subsidiary, or

                                    (D) an underwriter engaged in a distribution
                           of Company stock to the public with the Company's
                           written consent,

becomes the beneficial owner (as defined in Rule 13d-3 under the Exchange Act),
directly or indirectly, of Voting Securities that represent more than thirty
percent (30%) of the combined voting power of the then outstanding Voting
Securities. However, if the "person" in question is an institutional investor
whose investment in Voting Securities is purely passive when such person becomes
such a more than thirty percent beneficial owner of Voting Securities, then such
event (i.e., such person's becoming a more than thirty percent beneficial owner
of Voting Securities) shall not be deemed to constitute a Change in Control
under this subparagraph 11(a)(i) for so long as (and only for so long as) such
person's investment in Voting Securities remains purely passive; or

                                 page 15 of 20

<PAGE>

                           (ii)     the stockholders of the Company approve a
merger, consolidation, recapitalization or reorganization of the Company or a
Subsidiary, reverse split of any class of Voting Securities, or an acquisition
of securities or assets by the Company or a Subsidiary, or consummation of any
such transaction if stockholder approval is not obtained, other than (A) any
such transaction in which the holders of outstanding Voting Securities
immediately prior to the transaction receive, with respect to such Voting
Securities (or, in the case of a transaction in which the Company is the
surviving corporation or a transaction involving a Subsidiary, retain), voting
securities of the surviving or transferee entity representing more than fifty
percent (50%) of the total voting power outstanding immediately after such
transaction, with the voting power of each such continuing holder relative to
other such continuing holders not substantially altered in the transaction, or
(B) any such transaction which would result in a Related Party beneficially
owning more than 50 percent of the voting securities of the surviving entity
outstanding immediately after such transaction; or

                           (iii)    the stockholders of the Company approve a
plan of complete liquidation of the Company or an agreement for the sale or
disposition by the Company of all or substantially all of the Company's assets
other than any such transaction which would result in a Related Party owning or
acquiring more than 50 percent of the assets owned by the Company immediately
prior to the transaction; or

                           (iv)     the persons who were members of the Board of
Directors of the Company immediately before a tender or exchange offer for
shares of Common Stock by any person other than the Company or a Related Party,
or before a merger or consolidation of the Company or a Subsidiary, or contested
election of the Board of Directors of the Company, or before any combination of
such transactions, cease to constitute a majority of the Board of Directors of
the Company as a result of such transaction or transactions.

                  (b)      For purposes of paragraph 11(a) above:

                           (i)      the term "Related Party" shall mean (A) a
Subsidiary, (B) an employee or group of employees of the Company or any
Subsidiary, (C) a trustee or other fiduciary holding securities under an
employee benefit plan of the Company or any Subsidiary, or (D) a corporation or
other form of business entity owned directly or indirectly by the stockholders
of the Company in substantially the same proportion as their ownership of Voting
Securities;

                           (ii)     the term "Subsidiary means a corporation or
other form of business association of which shares (or other ownership
interests) having more than 50% of the voting power are, or in the future
become, owned or controlled, directly or indirectly, by the Company; and

                           (iii)    the term "Voting Securities" shall mean any
securities of the Company which carry the right to vote generally in the
election of directors.

                                 page 16 of 20

<PAGE>

                  (c)      For purposes of this Agreement, a "Potential Change
in Control" means that (i) the Company enters into an agreement, the
consummation of which would result in the occurrence of a Change of Control; or
(ii) the Board adopts a resolution to the effect that, for purposes of this
Agreement, a potential change in control of the Company has occurred.

         12.      Severability; Survival

                  (a)      In the event that any provision of this Agreement
shall be determined to be invalid or unenforceable for any reason, the remaining
provisions of this Agreement not so invalid or unenforceable shall be unaffected
thereby and shall remain in full force and effect to the fullest extent
permitted by law; and

                  (b)      Any provision of this Agreement which may for any
reason be invalid or unenforceable in any jurisdiction shall remain in effect
and be enforceable in any jurisdiction in which such provision shall be valid
and enforceable.

                  (c)      The provisions of sections 6, 7, 8, 9 and 10 of this
Agreement, and any other provision of this Agreement which is intended to apply,
operate or have effect after the expiration or termination of the term of this
Agreement, or at a time when the term of this Agreement may have expired or
terminated, shall survive the expiration or termination of the term of this
Agreement for any reason.

         13.      General Provisions

                  (a)      No right or interest to or in any payments to be made
under this Agreement shall be subject to anticipation, alienation, sale,
assignment, encumbrance, pledge, charge or hypothecation or to execution,
attachment, levy or similar process, or assignment by operation of law. All
payments to be made by the Company hereunder shall be subject to the withholding
of such amounts as the Company may determine it is required to withhold under
the laws or regulations of any governmental authority, whether foreign, federal,
state or local.

                  (b)      To the extent that the Employee acquires a right to
receive payments from the Company under this Agreement, such right shall be no
greater than the right of an unsecured general creditor of the Company. All
payments to be made hereunder shall be paid from the general funds of the
Company and no special or separate fund shall be established and no segregation
of assets shall be made to assure payment of any amount hereunder.

                  (c)      This Agreement shall be governed by and construed and
enforced in accordance with the laws of the State of New York, without giving
effect to the principles of conflicts of laws of that State.

                                 page 17 of 20

<PAGE>

                  (d)      This Agreement shall be binding upon and inure to the
benefit of the Company, its successors and assigns, and the Employee, his heirs,
devisees, distributees and legal representatives.

                  (e)      Any notice or other communication to the Company
pursuant to any provision of this Agreement shall be given in writing and will
be deemed to have been delivered:

                           (i)      when delivered in person to the Corporate
Secretary or General Counsel of the Company; or

                           (ii)     one week after it is deposited in the United
States certified or registered mail, postage prepaid, addressed to the Corporate
Secretary of the Company at 300 Corporate Drive, Building #10, Bradley Corporate
Park, Blauvelt, New York 10913 or at such other address of which the Company may
from time to time give the Employee written notice in accordance with paragraph
13(f) below.

                  (f)      Any notice or other communication to the Employee
pursuant to any provision of the Agreement shall be given in writing and will be
deemed to have been delivered:

                           (i)      when delivered to the Employee in person, or

                           (ii)     one week after it is deposited in the United
States certified or registered mail, postage prepaid, addressed to the Employee
at his address as it appears on the records of the Company or at such other
address of which the Employee may from time to time give the Company written
notice in accordance with paragraph 13(e) above.

                  (g)      No provision of this Agreement may be amended,
modified or waived unless such amendment, modification or waiver shall be agreed
to in a writing signed by the Employee and an authorized officer of the Company.

                  (h)      This instrument contains the entire agreement of the
parties relating to the subject matter of this Agreement and supersedes and
replaces all prior agreements and understandings with respect to such subject
matter, and the parties have made no agreements, representations or warranties
relating to the subject matter of this Agreement which are not set forth herein.

                                 page 18 of 20

<PAGE>

         IN WITNESS WHEREOF, the parties hereto have executed this Agreement as
of the date first above written.

                                              BARR LABORATORIES, INC.

                                              By: /s/ Catherine F. Higgins
                                                  ----------------------------
[SEAL]
Attest:

/s/ Phillandas Thompson
------------------------
Secretary                                     /s/ Bruce L. Downey
                                              -----------------------------
                                              Employee

                                 page 19 of 20

<PAGE>

                                                                        APPENDIX

 EXAMPLES ILLUSTRATING INTENDED OPERATION OF EXTENSION PROVISIONS OF PARAGRAPH 2

Example 1:

                  Facts: Neither the Company nor the Employee gives the other
                  party written notice of non-extension before the second
                  anniversary of the Commencement Date.

                  Result: Effective as of the second anniversary of the
                  Commencement Date, the term of the Agreement is extended 12
                  months, so that it will expire on the fourth anniversary of
                  the Commencement Date unless further extended in accordance
                  with the provisions of Paragraph 2 of the Agreement.

Example 2:

                  Facts: Either the Company or the Employee gives the other
                  party written notice of non-extension before the second
                  anniversary of the Commencement Date.

                  Result: The term of the Agreement is not extended, and expires
                  on the third anniversary of the Commencement Date.

Example 3:

                  Facts: Neither the Company nor the Employee gives the other
                  party written notice of non-extension before the third
                  anniversary of the Commencement Date.

                  Result: Effective as of the third anniversary of the
                  Commencement Date, the term of the Agreement as extended in
                  accordance with Example 1 above is further extended 12 months,
                  so that it will expire on the fifth anniversary of the
                  Commencement Date unless further extended in accordance with
                  the provisions of Paragraph 2 of the Agreement.

Example 4:

                  Facts: Either the Company or the Employee gives the other
                  party written notice of non-extension on or after the third
                  anniversary of the Commencement Date and before the fourth
                  anniversary of the Commencement Date.

                  Result: The term of the Agreement as extended is not further
                  extended, and expires on the fifth anniversary of the
                  Commencement Date.

                                 page 20 of 20

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