Document:

EX-4.12

 Exhibit 4.12 

THIS GLOBAL NOTE IS HELD BY THE DEPOSITARY (AS DEFINED IN THE INDENTURE GOVERNING THIS NOTE) OR ITS NOMINEE IN CUSTODY FOR THE BENEFIT OF THE
BENEFICIAL OWNERS HEREOF, AND IS NOT TRANSFERABLE TO ANY PERSON UNDER ANY CIRCUMSTANCES EXCEPT THAT (1) THE TRUSTEE MAY MAKE SUCH NOTATIONS HEREON AS MAY BE REQUIRED PURSUANT TO SECTION 2.06 OF THE INDENTURE,
(2) THIS GLOBAL NOTE MAY BE EXCHANGED IN WHOLE BUT NOT IN PART PURSUANT TO SECTION 2.06(a) OF THE INDENTURE, (3) THIS GLOBAL NOTE MAY BE DELIVERED TO THE TRUSTEE FOR CANCELLATION PURSUANT TO SECTION 2.09 OF THE INDENTURE AND
(4) THIS GLOBAL NOTE MAY BE TRANSFERRED TO A SUCCESSOR DEPOSITARY WITH THE PRIOR WRITTEN CONSENT OF THE ISSUER. 
 UNLESS AND UNTIL IT
IS EXCHANGED IN WHOLE OR IN PART FOR NOTES IN DEFINITIVE FORM, THIS NOTE MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY OR BY A NOMINEE OF THE DEPOSITARY TO THE DEPOSITARY OR ANOTHER NOMINEE OF THE
DEPOSITARY OR BY THE DEPOSITARY OR ANY SUCH NOMINEE TO A SUCCESSOR DEPOSITARY OR A NOMINEE OF SUCH SUCCESSOR DEPOSITARY. UNLESS THIS CERTIFICATE IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY (55 WATER STREET, NEW YORK,
NEW YORK) (“DTC”), TO THE ISSUER OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR SUCH OTHER NAME AS MAY BE REQUESTED BY AN AUTHORIZED
REPRESENTATIVE OF DTC (AND ANY PAYMENT IS MADE TO CEDE & CO. OR SUCH OTHER ENTITY AS MAY BE REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL
INASMUCH AS THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN. 

 HEALTHCARE REALTY HOLDINGS, L.P. 

2.050% Senior Notes Due 2031 
  

			
	 No. 2031-1
	  	
		
	 CUSIP No.:
	  	 42225UAM6

		
	 ISIN:
	  	 US42225UAM62

 $298,858,000 

Healthcare Realty Holdings, L.P., a Delaware limited partnership (f/k/a Healthcare Trust of America Holdings, LP, a Delaware
limited partnership) (herein called the “Issuer,” which term includes any successor entity under the Indenture referred to on the reverse hereof), for value received hereby promises to pay to Cede & Co., or its registered
assigns, the principal sum of two hundred ninety eight million, eight hundred fifty eight thousand dollars ($298,858,000), or such lesser amount as is set forth in the Schedule of Exchanges of Interests in the Global Note on the other side of this
Note, on March 15, 2031 at the office or agency of the Issuer maintained for that purpose in accordance with the terms of the Indenture, in such coin or currency of the United States of America as at the time of payment shall be legal tender
for the payment of public and private debts, and to pay interest, semi-annually on March 15 and September 15 of each year, commencing September 15, 2022, on said principal sum at said office or agency, in like coin or currency, at the
rate per annum of 2.050%, from the March 15 or September 15, as the case may be, next preceding the date to which interest has been paid or duly provided for, and in the case of the first interest payment on the Notes, from March 15,
2022, until payment of said principal sum has been made or duly provided for. The Issuer shall pay interest on any Notes in certificated form by check mailed to the address of the Person entitled thereto as it appears in the Note Register;
provided, however, that a Holder of any Notes in certificated form in the aggregate principal amount of more than $2.0 million may specify by written notice to the Issuer that it pay interest by wire transfer of immediately
available funds to the account specified by the Noteholder in such notice, or on any Global Note by wire transfer of immediately available funds to the account of the Depositary or its nominee. 

The Issuer promises to pay interest on overdue principal, premium, if any, and (to the extent that payment of such interest is
enforceable under applicable law) interest at the rate of 1% per annum above the rate borne by the Notes. 
 Reference is
made to the further provisions of this Note set forth on the reverse hereof and the Indenture governing this Note. Such further provisions shall for all purposes have the same effect as though fully set forth at this place. 

This Note shall not be valid or become obligatory for any purpose until the certificate of authentication hereon shall have
been signed manually or by facsimile or other electronic imaging means by the Trustee or a duly authorized authenticating agent under the Indenture. 

 IN WITNESS WHEREOF, the Issuer has caused this Note to be duly executed.

 Dated: July 22, 2022 
  

			
	 HEALTHCARE REALTY HOLDINGS, L.P.

		
	 By:
	 	 Healthcare Realty Trust Incorporated,

		 	 its general partner

		
	 By:
	 	 /s/ J. Christopher Douglas

	 Name:
	 	 J. Christopher Douglas

	 Title:
	 	 Chief Financial Officer

 TRUSTEE’S CERTIFICATE OF AUTHENTICATION 

This is one of the Notes described in the within-named Indenture. 

Dated: July 22, 2022 
  

			
	 U.S. Bank Trust Company, National Association, as Trustee

		
	 By:
	 	 /s/ Mary Ambriz-Reyes

	 Authorized Signatory

 [REVERSE SIDE OF NOTE] 

Healthcare Realty Holdings, L.P. 

2.050% Senior Notes Due 2031 

This Note is one of a duly authorized issue of Notes of the Issuer, designated as its 2.050% Senior Notes Due 2031 (herein
called the “Notes”), issued under and pursuant to an Indenture dated as of July 22, 2022 (herein called the “Base Indenture”), as supplemented by Supplemental Indenture No. 4 dated as of July 22, 2022
(“Fourth Supplemental Indenture” and together, the “Indenture”), among the Issuer, the Guarantor and U.S. Bank Trust Company, National Association, as trustee (herein called the “Trustee”),
to which Indenture and any indentures supplemental thereto reference is hereby made for a description of the rights, limitations of rights, obligations, duties and immunities thereunder of the Trustee, the Issuer, the Guarantor and the Holders of
the Notes. Defined terms used but not otherwise defined in this Note shall have the respective meanings ascribed thereto in the Indenture. 

If an Event of Default (other than an Event of Default specified in Section 6.01(e), 6.01(f)
or 6.01(g) of the Indenture with respect to the Issuer) occurs and is continuing, the principal of, premium, if any, and accrued and unpaid interest on all Notes may be declared to be due and payable by either the Trustee or the Holders of at
least twenty five percent (25%) in aggregate principal amount of the Notes then outstanding, and, upon said declaration the same shall be immediately due and payable. If an Event of Default specified in Section 6.01(e),
6.01(f) or 6.01(g) of the Indenture occurs with respect to the Issuer, the principal of and premium, if any, and interest accrued and unpaid on all the Notes shall be immediately and automatically due and payable without necessity of
further action. 
 The Indenture contains provisions permitting the Issuer and the Trustee, with the consent of the Holders
of not less than a majority in aggregate principal amount of the Notes at the time outstanding, to execute supplemental indentures adding any provisions to or changing in any manner or eliminating any of the provisions of the Indenture or of any
supplemental indenture or modifying in any manner the rights of the Holders of the Notes, subject to exceptions set forth in Section 9.02 of the Base Indenture. Subject to the provisions of the Indenture, the Holders of not
less than a majority in aggregate principal amount of the Notes at the time outstanding may, on behalf of the Holders of all of the Notes, waive any past Default or Event of Default, subject to exceptions set forth in the Indenture. 

No reference herein to the Indenture and no provision of this Note or of the Indenture shall impair, as among the Issuer and
the Holder of the Notes, the obligation of the Issuer, which is absolute and unconditional, to pay the principal of, premium, if any, on and interest on this Note at the place, at the respective times, at the rate and in the coin or currency herein
and in the Indenture prescribed. 
 Interest on the Notes shall be computed on the basis of a
360-day year of twelve 30-day months. 

 The Notes are issuable in fully registered form, without coupons, in
denominations of $2,000 principal amount and any multiple of $1,000. At the office or agency of the Issuer referred to on the face hereof, and in the manner and subject to the limitations provided in the Indenture, without payment of any service
charge but with payment of a sum sufficient to cover any tax, assessment or other governmental charge that may be imposed in connection with any registration or exchange of Notes, Notes may be exchanged for a like aggregate principal amount of Notes
of any other authorized denominations. 
 The Issuer shall have the right to redeem the Notes under certain circumstances as
set forth in Sections 3.01, 3.02 and 3.03 of the Indenture. 
 The Notes are not subject to redemption
through the operation of any sinking fund. 
 Except as expressly provided in Article 15 of the Indenture, no
recourse for the payment of the principal of or any premium or interest on this Note, or for any claim based hereon or otherwise in respect hereof, and no recourse under or upon any obligation, covenant or agreement of the Issuer in the Indenture or
any supplemental indenture or in any Note, or because of the creation of any indebtedness represented thereby, shall be had against any incorporator, stockholder, limited partner, member, manager, employee, agent, officer, director or subsidiary, as
such, past, present or future, of the Guarantor, the Issuer or any of the Issuer’s Subsidiaries or of any successor thereto, either directly or through the Guarantor, the Issuer or any of the Issuer’s subsidiaries or of any successor
thereto, whether by virtue of any constitution, statute or rule of law, or by the enforcement of any assessment or penalty or otherwise; it being expressly understood that all such liability is hereby expressly waived and released as a condition of,
and as consideration for, the execution of the Indenture and the issue of this Note. 

 ASSIGNMENT FORM 

To assign this Note, fill in the form below: 
  

			
	 (I) or (we) assign and transfer this Note to:
	 	  

	(Insert assignee’s legal name)

  
  

(Insert assignee’s soc. sec. or tax I.D. no.) 
  

 
  

 
  

 
  

 
 (Print or type assignee’s name,
address and zip code) 
  

			
	and irrevocably appoint	 	  

 to transfer this Note on the books of the Issuer. The agent may substitute another to act for him. 

Date:
                         
  

					
		 	Your Signature:	 	  

		 	 (Sign exactly as your name appears on the face of this Note)

 Signature Guarantee*:
                     
  

	*	 Participant in a recognized Signature Guarantee Medallion Program (or other signature guarantor acceptable
to the Trustee). 

 SCHEDULE OF EXCHANGES OF INTERESTS IN THE GLOBAL NOTE * 

The following exchanges of a part of this Global Note for an interest in another Global Note or for a Definitive Note, or
exchanges of a part of another Global Note or Definitive Note for an interest in this Global Note, have been made: 
  

									
	 Date of Exchange
	  	 Amount of

decrease in

Principal
 Amount at

maturity of this
 Global
Note
	  	 Amount of

increase in

Principal
 Amount at

maturity of
 this
Global
 Note
	  	 Principal Amount

at maturity of this
 Global
Note
 following such

decrease
 (or
increase)
	  	 Signature of

authorized
 officer of
Trustee
 or Custodian

  

 

	*	 This schedule should be included only if the Note is issued in global form.EX-4.13

 Exhibit 4.13 

GUARANTEE 
 The
Guarantor listed below (hereinafter referred to as the “Guarantor,” which term includes any successors or assigns under the Indenture, dated as of July 22, 2022 (herein called the “Base Indenture”), as
supplemented by Supplemental Indenture No. 1 dated as of July 22, 2022 (“First Supplemental Indenture” and together, the “Indenture”), among the Guarantor, the Issuer (as defined below) and U.S.
Bank Trust Company, National Association, as trustee), has irrevocably and unconditionally guaranteed on a senior basis the Guarantee Obligations (as defined in Section 15.01 of the First Supplemental Indenture), which
include (i) the due and punctual payment of the principal of, premium, if any, and interest on the 3.875% Senior Notes Due 2025 (the “Notes”) of Healthcare Realty Holdings, L.P., a Delaware limited partnership (f/k/a Healthcare
Trust of America Holdings, LP, a Delaware limited partnership) (the “Issuer”), whether at maturity, by acceleration, call for redemption or otherwise, the due and punctual payment of interest on the overdue principal and premium, if
any, and (to the extent permitted by law) interest on any interest on the Notes, and the due and punctual performance of all other obligations of the Issuer, to the Holders of the Notes or the Trustee all in accordance with the terms set forth in
Article 15 of the First Supplemental Indenture, and (ii) in case of any extension of time of payment or renewal of any Notes or any such other obligations, that the same shall be promptly paid in full when due or performed in accordance
with the terms of the extension or renewal, whether at maturity, by acceleration, call for redemption or otherwise. 
 The obligations of
the Guarantor to the Holders of the Notes and to the Trustee pursuant to this Guarantee and the First Supplemental Indenture are expressly set forth in Article 15 of the First Supplemental Indenture and reference is hereby made to such First
Supplemental Indenture for the precise terms of this Guarantee. 
 No past, present or future director, officer, employee, incorporator or
stockholder (direct or indirect) of the Guarantor (or any such successor entity), as such, shall have any liability for any obligations of the Guarantor under this Guarantee or the First Supplemental Indenture or for any claim based on, in respect
of, or by reason of, such obligations or their creation. 
 The Guarantor hereby waives diligence, presentment, demand of payment, filing of
claims with a court in the event of merger or bankruptcy of the Issuer, any right to require a proceeding first against the Issuer, the benefit of discussion, protest or notice with respect to the Notes and all demands whatsoever. 

This is a continuing Guarantee and shall remain in full force and effect and shall be binding upon the Guarantor and its successors and
assigns until full and final payment of all of the Issuer’s obligations under the Notes and Indenture or until legally discharged in accordance with the First Supplemental Indenture and shall inure to the benefit of the successors and assigns
of the Trustee and the Holders of the Notes, and, in the event of any transfer or assignment of rights by any Holder of the Notes or the Trustee, the rights and privileges herein conferred upon that party shall automatically extend to and be vested
in such transferee or assignee, all subject to the terms and conditions hereof. This is a Guarantee of payment and performance and not of collectability. 

This Guarantee shall not be valid or obligatory for any purpose until the certificate of authentication on the Note upon which this Guarantee
is noted shall have been signed, in the name and on behalf of the Trustee under the First Supplemental Indenture, manually by one of the authorized officers of the Trustee under the Indenture. 

 The obligations of the Guarantor under this Guarantee shall be limited to the extent
necessary to insure that it does not constitute a fraudulent conveyance under applicable law. 
 THE TERMS OF ARTICLE 15 OF THE
INDENTURE ARE INCORPORATED HEREIN BY REFERENCE. 
 Capitalized terms used herein have the same meanings given in the First Supplemental
Indenture unless otherwise indicated. 

 IN WITNESS WHEREOF, the Guarantor has caused this instrument to be duly
executed. 
 Dated: July 22, 2022 
  

			
	 HEALTHCARE REALTY TRUST INCORPORATED

		
	 By:
	 	 /s/ J. Christopher Douglas

	 Name:
	 	 J. Christopher Douglas

	 Title:
	 	 Chief Financial Officer

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