Document:

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                                                                    EXHIBIT 10.2

                              AMENDED AND RESTATED
                     MOLECULAR INSIGHT PHARMACEUTICALS, INC.
                           2006 EQUITY INCENTIVE PLAN

                         NONQUALIFIED STOCK OPTION AWARD

[Name]
[Address]

Dear _____________________:

You have been granted an option (the "OPTION") to purchase shares of common
stock of Molecular Insight Pharmaceuticals, Inc. (the "COMPANY") under the
Amended and Restated Molecular Insight Pharmaceuticals, Inc. 2006 Equity
Incentive Plan (the "PLAN") with the following terms and conditions:

Grant Date:                __________, 20___

Type of Option:            Nonqualified Stock Option

Number of Option Shares:   __________________

Exercise Price per Share:  U.S. $_____________

Expiration:                Close of business at the Company headquarters on the
                           tenth (10th) anniversary of the Grant Date, subject
                           to earlier termination as described under
                           "Termination of Employment or Service Arrangement."

Vesting:                   One Hundred percent (100%) of your Option will vest
                           in accordance with the following schedule, provided
                           you are continuously employed by, or continuously
                           provide services to, the Company or an Affiliate
                           until the applicable vesting date: 1

                              Percent of
                             Option Vested      Vesting Date
                             -------------      ------------
                           25%                 1st anniversary of the Grant Date
                           An additional 25%   2nd anniversary of the Grant Date
                           An additional 25%   3rd anniversary of the Grant Date
                           An additional 25%   4th anniversary of the Grant Date

                           [_____ PERCENT (__%) OF YOUR OPTION WILL VEST ON
                           ACHIEVEMENT OF PERFORMANCE GOALS AS SPECIFIED IN
                           SCHEDULE A TO THIS STOCK

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1 Nonqualified stock options granted to Non-Employee Directors under automatic
granting provisions under the Plan become exercisable in full on and after the
first anniversary of the date of grant.

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                                       OPTION AWARD, PROVIDED YOU ARE
                                       CONTINUOUSLY EMPLOYED BY, OR CONTINUOUSLY
                                       PROVIDE SERVICES TO, THE COMPANY OR AN
                                       AFFILIATE UNTIL THE PERFORMANCE
                                       GOALS ARE ACHIEVED.] 2

                                       Upon termination of your employment or
                                       service arrangement with the Company
                                       and its Affiliates for any other reason
                                       (other than for Cause), the unvested
                                       portion of your Option will terminate on
                                       the date of such termination.

                                       In the event of a Change of Control of
                                       the Company, your Option will be
                                       treated as provided in Section 14(c) of
                                       the Plan.

Manner of Exercise:                    You may exercise your Option only to the
                                       extent vested and only if the Option
                                       has not terminated. To exercise your
                                       Option, you must complete the "Notice
                                       of Stock Option Exercise" form provided
                                       by the Company and return it to the
                                       address indicated on the form. Your form
                                       must specify how many shares you
                                       wish to purchase and will explain how you
                                       must satisfy the exercise price and
                                       withholding taxes due, if any, upon
                                       exercise. The form will be effective
                                       when it is received by the Company.

                                       If someone else wants to exercise your
                                       Option after your death, that person
                                       must contact the Company and prove to the
                                       Company's satisfaction that he or
                                       she is entitled to do so. Your ability to
                                       exercise the Option may be restricted by
                                       the Company if required by applicable
                                       law, any Company policy or any agreement
                                       between the Company and its underwriters.

Termination of Employment or Service   If your employment or service arrangement
Arrangement:                           terminates your Option will terminate on
                                       the close of business at the Company
                                       headquarters as follows: 3

                                       -        If your employment or service
                                                arrangement terminates as a
                                                result of death or Disability
                                                (at a time when your employment
                                                or service arrangement could not
                                                have been terminated for Cause),
                                                the vested portion of your
                                                Option will terminate ninety
                                                (90) calendar days after the
                                                date of the termination.

                                       -        If your employment terminates as
                                                a result of your Retirement, the
                                                vested portion of your Option
                                                will terminate ninety (90)
                                                calendar days after the date of
                                                your termination of employment.
</TABLE>

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2  If a milestone provision is included, the vesting percentage subject to four
equal annual installments needs to be proportionally reduced.

3. Nonqualified stock options granted to a Non-Employee Director under automatic
granting provisions under the Plan terminate ninety (90) calendar days after
such Non-Employee Director ceases to be a director of the Company for any
reason, including as a result of the Non-Employee Director's death, disability
or retirement.

                                       2

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                                       -        If your employment or service
                                                arrangement terminates for any
                                                other reason (other than for
                                                Cause, as described below), the
                                                vested portion of your Option
                                                will terminate ninety (90)
                                                calendar days after the date of
                                                the termination.

                                       If your employment or service arrangement
                                       is terminated for Cause, your
                                       entire Option (whether vested or
                                       nonvested) is terminated immediately. In
                                       addition, if you have submitted a notice
                                       of exercise that has not yet been
                                       processed and your employment or service
                                       arrangement is terminated for Cause,
                                       your notice of exercise will be rescinded
                                       and your exercise price will be
                                       returned to you.

Transferability:                       You may not transfer or assign your
                                       Option for any reason, other than under
                                       your will or as required by intestate
                                       laws. Any attempted transfer or
                                       assignment in violation of this provision
                                       will be null and void. During your
                                       lifetime, only you (or your guardian or
                                       legal representative if approved by
                                       the Company in the event of your
                                       incapacity) are entitled to exercise the
                                       Option.

Restrictions on Resale:                By accepting the Option, you agree not to
                                       sell any Shares acquired under the
                                       Option at a time when applicable laws,
                                       Company policies or an agreement
                                       between the Company and its underwriters
                                       prohibit a sale.

Miscellaneous:                         -        This Stock Option Award may be
                                                amended only by written consent
                                                signed by you and the Company,
                                                except to the extent the
                                                amendment is not to your
                                                detriment or the Committee deems
                                                it necessary to comply
                                                with any applicable law or
                                                listing requirement of any
                                                principal securities exchange or
                                                market on which the Company's
                                                common stock is then traded, or
                                                to preserve favorable accounting
                                                treatment of the Option for the
                                                Company.

                                       -        As a condition of the granting
                                                of the Option, you agree, for
                                                yourself and your legal
                                                representatives or guardians,
                                                that this Stock Option Award
                                                shall be interpreted by the
                                                Committee and that any
                                                interpretation by the Committee
                                                of the terms of this Stock
                                                Option Award and any
                                                determination made by the
                                                Committee pursuant to this Stock
                                                Option Award shall be final,
                                                binding and conclusive.

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                                       3
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                                       -        This Stock Option Award may be
                                                executed in counterparts.
</TABLE>

The Option is granted under and governed by the terms and conditions of the
Plan. Additional provisions regarding your Option and definitions of capitalized
terms used and not defined in this Stock Option Award can be found in the Plan.

                                         MOLECULAR INSIGHT PHARMACEUTICALS, INC.

                                         By:
                                            ------------------------------------
                                              Authorized Officer

                              OPTIONEE'S ACCEPTANCE

BY SIGNING BELOW AND ACCEPTING THIS STOCK OPTION AWARD, YOU AGREE TO ALL OF THE
TERMS AND CONDITIONS DESCRIBED HEREIN AND IN THE PLAN, AND YOU ALSO ACKNOWLEDGE
RECEIPT OF THE PLAN IN ITS ENTIRETY AND THE SUMMARY OF THE PLAN, WHICH
CONSTITUTES PART OF A PROSPECTUS COVERING SECURITIES THAT HAVE BEEN REGISTERED
UNDER THE SECURITIES ACT OF 1933, AS AMENDED, AND MEETS THE REQUIREMENTS OF
SECTION 10(a) OF SAID ACT.

                                         ---------------------------------------
                                         Optionee Signature
                                         Print Name:
                                                    ----------------------------

                                       4Exhibit 4.1
	 

	 
		EXECUTION VERSION
	 

	 
		

	 

	 
		MIDAMERICAN ENERGY COMPANY
	 

	 
		and
	 

	 
		THE BANK OF NEW YORK TRUST COMPANY, N.A.,
 as Trustee
	 

	 
		________________
	 

	 
		5.65% Senior Notes due 2012
	 

	 
		5.95% Senior Notes due 2017
	 

	 
		________________
	 

	 
		Second Supplemental Indenture
	 

	 
		________________
	 

	 
		Dated as of June 29, 2007
	 

	 
		

	 

	 
		
 

	 

	 
		

	 

	 
		

	 

	 
 
	 
		

	 

	 
		

	 

	 
		SECOND SUPPLEMENTAL INDENTURE, dated as of June 29, 2007 (herein called
		the “Second Supplemental Indenture”), between MIDAMERICAN
		ENERGY COMPANY, a corporation duly organized and existing under the laws of the
		State of Iowa (herein called the “Company”), and THE BANK OF
		NEW YORK TRUST COMPANY, N.A., a New York banking association duly organized and
		existing under the laws of the United States of America, as Trustee (herein
		called the “Trustee”), under the Original Indenture referred
		to below.
	 

	 
		W I T N E S S E T H :
	 

	 
		WHEREAS, the Company has heretofore executed and delivered to the Trustee
		an indenture dated as of October 1, 2006 (herein called the “Original
		Indenture”), to provide for the issuance from time to time of its
		unsubordinated debentures, notes or other evidences of indebtedness, the form
		and terms of which are to be established as set forth in Sections 2.01 and 3.01
		of the Original Indenture;
	 

	 
		WHEREAS, the Company has heretofore executed and delivered to the Trustee
		a first supplemental indenture dated as of October 6, 2006, as amended (herein
		called the “First Supplemental Indenture”), to provide for the
		issuance of up to an aggregate principal amount of three hundred fifty million
		dollars ($350,000,000) of its 5.800% Notes due 2036 under the Original
		Indenture;
	 

	 
		WHEREAS, Section 9.01 of the Original Indenture provides, among other
		things, that the Company and the Trustee may enter into indentures supplemental
		to the Original Indenture for, among other things, (i) the purpose of
		establishing the form and terms of the Securities (as defined in the Original
		Indenture) of any series as permitted by Sections 2.01 and 3.01 of the Original
		Indenture, and (ii) to add to the covenants of the Company for the benefit of
		the Holders of all or any series of Securities (as defined in the Original
		Indenture);
	 

	 
		WHEREAS, the Company desires to create two series of its unsecured
		securities, one series of its securities in an aggregate principal amount of
		Two Hundred Fifty Million Dollars ($250,000,000) to be designated the
		“5.95% Senior Notes due 2017” and one series of its securities in an
		aggregate principal amount of Four Hundred Million Dollars ($400,000,000) to be
		designated the “5.65% Senior Notes due 2012” (together, the
		“Securities”), and all action on the part of the Company
		necessary to authorize the issuance of the Securities under the Original
		Indenture and this Second Supplemental Indenture has been duly taken;
	 

	 
		WHEREAS, the Company and the Trustee desire to make certain amendments to
		the Original Indenture in conformance with the requirements described above;
		and
	 

	 
		
 

	 

	 
		1
	 

	 
		

	 

	 
		

	 

	 
 
	 
		

	 

	 
		

	 

	 
		WHEREAS, all acts and things necessary to make the Securities, when
		executed by the Company and authenticated and delivered by the Trustee as
		provided in the Original Indenture, the valid and binding obligations of the
		Company and to constitute these presents a valid and binding supplemental
		indenture and agreement according to its terms, have been done and performed.
	 

	 
		NOW, THEREFORE, THIS SECOND SUPPLEMENTAL INDENTURE WITNESSETH:
	 

	 
		That in consideration of the premises and of the acceptance and purchase
		of the Securities by the holders thereof and of the acceptance of this trust by
		the Trustee, the Company covenants and agrees with the Trustee, for the equal
		benefit of holders of the Securities, as follows:
	 

	 
		ARTICLE I
 DEFINITIONS
	 

	 
		Unless otherwise defined herein, the use of the terms and expressions
		herein is in accordance with the definitions, uses and constructions contained
		in the Original Indenture and the forms of Securities attached hereto as
		Exhibits A and B.
	 

	 
		ARTICLE II
 TERMS AND ISSUANCE OF THE SECURITIES
	 

	 
		Section 2.01.  Issue of Securities.  Two series of debt
		securities, which shall be designated the “5.65% Senior Notes due
		2012” and the “5.95% Senior Notes due 2017”, respectively, shall
		be executed, authenticated and delivered in accordance with the provisions of,
		and shall in all respects be subject to, the terms, conditions and covenants of
		the Original Indenture and this Second Supplemental Indenture (including the
		forms of Securities set forth in Exhibits A and B).  
	 

	 
		Section 2.02.  Optional Redemption.  The Securities may
		be redeemed, in whole or in part, at the option of the Company pursuant to the
		terms set forth in Annex 1 to the Securities to be redeemed.  The
		provisions of Article XI of the Original Indenture shall also apply to any
		optional redemption of Securities by the Company.
	 

	 
		Section 2.03.  Defeasance and Discharge.  The provisions
		of Section 14.02 of the Original Indenture shall be applicable to the
		Securities.
	 

	 
		Section 2.04.  Covenant Defeasance.  The provisions of
		Section 14.03 of the Original Indenture shall be applicable to the Securities.
	 

	 
		
 

	 

	 
		2
	 

	 
		

	 

	 
 
	 
		

	 

	 
		

	 

	 
		Section 2.05.  Place of Payment.  The Place of Payment
		in respect of the Securities will be initially at the Corporate Trust Office of
		The Bank of New York Trust Company, N.A. (which as of the date hereof is
		located at 2 N. LaSalle Street, Suite 1020, Chicago, Illinois 60602, Attention:
		 Corporate Trust Administration).
	 

	 
		Section 2.06.  Form of Securities; Incorporation of Terms.
		 The forms of the Securities shall be substantially in the forms of
		Exhibit A and B, as applicable, the respective terms of which are herein
		incorporated by reference and which are part of this Second Supplemental
		Indenture.  Each series of the Securities shall be issued as one or more
		Global Securities in fully registered form, as determined in accordance with
		Section 2.01 of the Original Indenture.  The Global Securities shall be
		delivered by the Trustee to the Depositary, as the Holder thereof, or a nominee
		or custodian therefore, to be held by the Depositary in accordance with the
		Original Indenture.
	 

	 
		Section 2.07.  Exchange of the Global Securities.  Each
		of the Global Securities shall be exchangeable for definitive Securities only
		as provided in Section 3.05 of the Original Indenture.
	 

	 
		Section 2.08.  Regular Record Date for the Securities.
		 The Regular Record Date for the Securities shall be the first of January
		or the first of July immediately prior to each Interest Payment Date.
	 

	 
		Section 2.09.  Authorized Denominations.  Beneficial
		interests in Global Securities, as well as definitive Securities, may be held
		only in denominations of $2,000 and integral multiples of $1,000 in excess
		thereof.
	 

	 
		Section 2.10.  Additional Securities.  The Company may
		from time to time, without the consent of the Holders of the Securities, create
		and issue further securities having the same terms and conditions as the
		Securities in all respects, except for the original issue date and offering
		price. Additional Securities of each series issued in this manner will be
		consolidated with, and form a single series with, the Securities of such series
		and shall thereafter be deemed Securities for all purposes.
	 

	 
		ARTICLE III
 DEPOSITARY
	 

	 
		Section 3.01.  Depositary.  The Depositary Trust
		Company, its nominees and their respective successors are hereby appointed
		Depositary with respect to the Global Securities of each series.
	 

	 
		ARTICLE IV
 MISCELLANEOUS
	 

	 
		
 

	 

	 
		3
	 

	 
		

	 

	 
 
	 
		

	 

	 
		

	 

	 
		Section 4.01.  Execution as Supplemental Indenture.
		 This Second Supplemental Indenture is executed and shall be construed as
		an indenture supplemental to the Original Indenture and, as provided in the
		Original Indenture, this Second Supplemental Indenture forms a part thereof.
	 

	 
		Section 4.02.  Effect of Headings.  The Article and
		Section headings herein are for convenience only and shall not affect the
		construction hereof.
	 

	 
		Section 4.03.  Successors and Assigns.  All covenants
		and agreements contained in this Second Supplemental Indenture made by the
		Company shall bind its successors and assigns, whether so expressed or not.
	 

	 
		Section 4.04.  Separability Clause.  In case any
		provision in this Second Supplemental Indenture or in the Securities shall be
		invalid, illegal or unenforceable, the validity, legality and enforceability of
		the remaining provisions shall not in any way be affected or impaired thereby.
	 

	 
		Section 4.05.  Benefits of Second Supplemental Indenture.
		 Nothing in this Second Supplemental Indenture or in the Securities,
		express or implied, shall give to any person, other than the parties hereto and
		their successors hereunder and the Holders of the Securities, any benefit or
		any legal or equitable right, remedy or claim under this Second Supplemental
		Indenture.
	 

	 
		Section 4.06.  Execution and Counterparts.  This Second
		Supplemental Indenture may be executed in any number of counterparts, each of
		which shall be deemed to be an original, but all such counterparts shall
		together constitute but one and the same instrument.
	 

	 
		Section 4.07.  Trustee Not Responsible for Recitals.
		 The recitals herein contained are made by the Company and not by the
		Trustee, and the Trustee assumes no responsibility for the correctness thereof.
		 The Trustee makes no representation as to the validity or sufficiency of
		this Second Supplemental Indenture or of the Securities.  The Trustee
		shall not be accountable for the use or application by the Company of the
		Securities or the proceeds thereof.
	 

	 
		[SIGNATURE PAGE FOLLOWS]
 
	 

	 
		
 

	 

	 
		4
	 

	 
		

	 

	 
 
	 
		

	 

	 
		

	 

	 
		IN WITNESS WHEREOF, the parties hereof have caused this Second
		Supplemental Indenture to be duly executed by their respective officers or
		directors duly authorized thereto, all as of the day and year first above
		written.
	 

	 			
	
			 
				 
			 

		  	
			 
				MIDAMERICAN ENERGY COMPANY
			 

		  
	
			 
				 
			 

		  	
			 
				 
			 

		  	
			 
				 
			 

		  
	
			 
				 
			 

		  	
			 
				By:
			 

		  	
			 
				    /s/   Brian K.
				Hankel            
			 

		  
	
			 
				 
			 

		  	
			 
				 
			 

		  	
			 
				Name: Brian K. Hankel
 Title: Vice President and Treasurer
			 

		  
	
			 
				 
			 

		  	
			 
				 
			 

		  	
			 
				 
			 

		  
	
			 
				 
			 

		  	
			 
				 
			 

		  	
			 
				 
			 

		  
	
			 
				 
			 

		  	
			 
				THE BANK OF NEW YORK TRUST COMPANY, N.A.,
 as Trustee
			 

		  
	
			 
				 
			 

		  	
			 
				By:
			 

		  	
			 
				  /s/  Roxane Ellwanger
			 

		  
	
			 
				 
			 

		  	
			 
				 
			 

		  	
			 
				Name: Roxane Ellwanger
 Title: Assistant Vice President
			 

		  

	 
		

	 

	 
		
 

	 

	 
		5

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