Document:

EX-10.24

 Exhibit 10.24 

November 12, 2012 

Convertible Bridge Loan Agreement 

Dated November 12, 2012 

between 
  

	1.	Pieris AG, whose principal place of business is at Lise-Meitner-Str. 30, 85354 Freising, Germany (the “Company”), represented by its management board, consisting of Stephen Yoder, Claus Schalper
and Dr. Laurent Audoly, and its supervisory board, being represented by its chairman, Dr. Hans A. Küpper, and  

  

	2.	the persons listed in Exhibit A, who are the shareholders of the Company (the “Shareholders”). 

  

	3.	The Company and the Shareholders shall be jointly referred to as the “Parties”. 

Preamble 
  

	1.	The Shareholders are the current holders of all shares in the Company, which is registered in the commercial register of the local court of Munich (hereinafter referred to as the “Commercial Register”)
under no. HRB 133223. The object of the Company is biotechnological research as well as the development and distribution of the research results. 

  

	2.	With regard to the Company a series of rounds of financing providing for equity capital were closed and corresponding agreements were entered into, in particular the Investment Agreement and the Shareholders Agreement
both dated October 23, 2002, the Investment Agreement dated October 14, 2004 (file no. V2519/2004 of the notary Dr. Oliver Vossius, Munich) and the Investment Agreement and the Shareholders Agreement both dated November 13, 2006.
All aforementioned agreements were consolidated and replaced by the Consolidated Shareholders’ Agreement 2008 and Investment Agreement both dated March 26, 2008. 

	3.	The current shareholding in the Company is as follows: 

  

																	
	 Name of Shareholder
	  	Number of
Common
Shares	 	  	Number of
Preferred
Shares Series
A	 	  	Number of
Preferred
Shares
Series A-1	 	  	Number of
Preferred
Shares
Series B	 
	 Prof. Skerra Bet. GmbH
	  	 	43,663	  	  				  				  			
	 Dr. Steffen Schlehuber
	  	 	1,162	  	  				  				  			
	 Claus Schalper
	  	 	870	  	  				  				  			
	 Dr. Karsten Schürrle
	  	 	584	  	  				  				  			
	 MAPO Bet. GmbH
	  	 	5,664	  	  				  				  			
	 BioM AG
	  	 	2,950	  	  				  				  	 	1,852	  
	 BioM Venture Capital GmbH & Co. KG
	  	 	1,870	  	  	 	40,537	  	  	 	8,277	  	  	 	5,926	  
	 Transconnect Corporate Finance Beratungs GmbH
	  	 	3,230	  	  	 	6,755	  	  	 	2,570	  	  	 	6,189	  
	 The Global Life Science Ventures Fonds II GmbH & Co. KG
	  				  	 	45,606	  	  	 	17,358	  	  	 	31,035	  
	 The Global Life Science Ventures Fund II LP
	  				  	 	35,474	  	  	 	13,501	  	  	 	24,139	  
	 Gilde Europe Food & Agribusiness Fund B.V.
	  				  	 	81,080	  	  	 	30,858	  	  	 	55,174	  
	 Baytech Venture Capital GmbH & Co. KG
	  				  	 	60,812	  	  	 	9,312	  	  	 	9,312	  
	 Coöperatieve AAC LS U.A.
	  				  	 	54,049	  	  	 	14,070	  	  	 	33,575	  
	 KfW
	  				  				  	 	22,973	  	  	 	11,324	  
	 Technologie Beteiligungsfonds II Bayern GmbH & Co. KG
	  				  				  	 	13,513	  	  	 	6,659	  
	 Orbimed Private Investments III, LP
	  				  				  				  	 	183,438	  
	 Orbimed Associates III, LLC
	  				  				  				  	 	1,747	  
	 Novo Nordisk A/S
	  				  				  				  	 	92,593	  
		  	  
	  
	 	  	  
	  
	 	  	  
	  
	 	  	  
	  
	 
	 Total
	  	 	59,993	  	  	 	324,313	  	  	 	132,432	  	  	 	462,963	  
		  	  
	  
	 	  	  
	  
	 	  	  
	  
	 	  	  
	  
	 

  

	4.	The Company now seeks a bridge financing amounting to a total of EUR 2,000,000 in this financing round (the “2012 Financing Round”) to be provided by a convertible bridge loan granted to the Company by
those shareholders of the Company listed in the table in Sec. 1 para. (2) of this Convertible Bridge Loan Agreement (the “Investors”). 

 

	5.	 To this end, the Investors intend to make available to the Company a bridge loan in the total amount of EUR 2,000,000 which shall be convertible into
shares of the Company, subject to the terms and conditions of this Convertible Bridge Loan Agreement. The Investors were initially offered an investment in the Convertible Bridge Loan pro rata their shareholding in the shares of the Company. As one
or several Investors did not participate in the granting of the Convertible Bridge Loan with their pro rata share of the loan, the 

  

–    2 / 25 – 

	 	
remaining principal amount of the Convertible Bridge Loan was offered to the other Investors pro rata their shareholding among such other Investors, resulting in the principal amount of the
Convertible Bridge Loan being divided as displayed in Sec. 1 para. (2) of this Convertible Bridge Loan Agreement. 

  

	6.	The Parties intend to regulate their current and future relationship as shareholders of the Company by entering into a separate consolidated shareholders’ agreement (the “CSA 2012”), attached
hereto as Exhibit B. The CSA 2012 shall form an integral part of this Convertible Bridge Loan Agreement. Terms used but not defined herein shall have the same meaning as given to them in the CSA 2012. Upon this Convertible Bridge Loan
Agreement and the CSA 2012 coming into force, all prior agreements between the undersigning parties regulating their relationship as shareholders of the Company, including but not limited to the agreements mentioned in para. (2) of this
Preamble, are terminated and finally superseded. 

  

	7.	It is the common intention of the Parties that the shares of the Company are listed at a stock exchange or that the Company or all or part of its assets are sold or licensed to a third party on or before the Maturity
Date (as such term is defined below) in order to repay the Convertible Bridge Loan on or before the Maturity Date. 

 NOW,
THEREFORE, the Parties hereto enter into the following Convertible Bridge Loan Agreement (hereinafter referred to as this “Agreement”): 

Sec. 1. 
 Convertible
Bridge Loan 
  

	1.	Subject to subject to the terms and conditions of this Agreement, the Investors grant to the Company a loan in the amount of Euro 2,000,000 which shall be convertible into shares of the Company, subject to the terms and
conditions of this Agreement (the “Convertible Bridge Loan”). 

  

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	2.	The principal amount of the Convertible Bridge Loan shall be divided between the Investors as follows (individually a “Loan Amount” and collectively, the “Loan Amounts”):

  

					
	 Investor
	  	Loan Amount in EUR	 
	 Orbimed Private Investments III, LP
	  	 	492.113	  
	 Orbimed Associates III, LLC
	  	 	4.687	  
	 Novo Nordisk A/S
	  	 	199.606	  
	 Transconnect Corporate Finance Beratungs GmbH
	  	 	50.285	  
	 BioM AG
	  	 	164.751	  
	 BioM Venture Capital GmbH & Co. KG
	  	 	0	  
	 The Global Life Science Ventures Fonds II GmbH & Co. KG
	  	 	252.173	  
	 The Global Life Science Ventures Fund II LP
	  	 	196.145	  
	 Gilde Europe Food & Agribusiness Fund B.V.
	  	 	421.015	  
	 Baytech Venture Capital GmbH & Co. KG
	  	 	0	  
	 Coöperatieve AAC LS U.A.
	  	 	219.225	  
	 KfW
	  	 	0	  
	 Technologie Beteiligungsfonds II Bayern GmbH & Co. KG (BayernKapital)
	  	 	0	  
		  	  
	  
	 
	 Total
	  	 	2,000,000.00	  
		  	  
	  
	 

  

	3.	All Shareholders hereby expressly consent to the distribution of the principal amount of the Convertible Bridge Loan among the Investors pursuant to para. (2) of this Sec. 1 and waive any subscription rights or
similar rights in relation to the Convertible Bridge Loan. 

  

	4.	The Loan Amounts shall be paid out by the Investors to the Company within ten (10) bank working days in Frankfurt/Main, Germany, after the closing of this Agreement to an account submitted by the Company to the
Investors in writing. 

 Sec. 2. 

Use of proceeds 
 The
Company shall use the Convertible Bridge Loan solely for general corporate purposes. 
 Sec. 3. 

Term 
 The Convertible
Bridge Loan is granted until December 31, 2013 (the “Maturity Date”). 

  

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 Sec. 4. 

Interest 
 The Loan Amounts
shall bear interest on the amount outstanding until the Loan Amounts are repaid at a rate of 12% per annum on or before the Maturity Date. If and to the extent the Loan Amounts have not been repaid by the Maturity Date, the Loan Amounts shall
from then on bear interest on the amount outstanding at a rate of 18% per annum. The interest is to be calculated on the basis of a year with 360 days with 12 months of 30 days each. The interest on the Loan Amounts is due and payable upon
repayment of the Loan Amounts to the Investors. If the Convertible Bridge Loan is converted into shares of the Company as provided in this Agreement, the respective formula set out in Sec. 11 of this Agreement shall apply. 

Sec. 5. 
 Termination and
Repayment 
  

	1.	The Investors are entitled to terminate the Convertible Bridge Loan and request the repayment of the Loan Amounts plus any interest accrued thereon 

 

	 	a.	on or at any time after the Maturity Date or 

  

	 	b.	in case of the closing of an Exit Event (as such term is defined in Sec. 11 para (1) of the CSA 2012) or 

  

	 	c.	in case of the closing of a financing of the Company lead by a financial or strategic investor currently not affiliated with the Company resulting in aggregate proceeds available to the Company of not less than EUR
10,000,000 (“Qualified Financing”), or 

  

	 	d.	in case of the closing of a partnering, collaboration, license or any similar business agreement resulting in aggregate proceeds available to the Company of not less than EUR 5,000,000, the termination of the
Convertible Bridge Loan in accordance with this lit. (d) requiring, to be effective, the consent of the supervisory board of the Company, which shall pass a resolution based on the needs of the Company. 

  

–    5 / 25 – 

	2.	The Company and the Investors are entitled to terminate the Convertible Bridge Loan for good cause (aus wichtigem Grund) at any time. Furthermore and notwithstanding the foregoing, each Investor individually is
entitled to terminate the respective Loan Amount. Good cause for the Investors includes, without limitation, the following events: 

  

	 	a.	voluntary bankruptcy / insolvency events (in particular if the Company is insolvent within the meaning of § 17 German Insolvency Code (Insolvenzordnung) or if the Company applies for such proceedings to be
commenced or offers an out-of-court settlement in order to avoid such proceedings); or 

  

	 	b.	the opening of involuntary bankruptcy / insolvency proceedings (ErÖffnung eines Insolvenzverfahrens) over the Company’s assets. 

 

	3.	The termination right pursuant to para. (1) and (2) of this Sec. 5 must be exercised in writing. 

  

	4.	In case the Convertible Bridge Loan or a Loan Amount is validly terminated, the Company is obliged to repay the Loan Amounts or Loan Amount, respectively (plus interest accrued until that date), within five
(5) bank working days in Frankfurt/Main, Germany. 

 Sec. 6. 

Payments 
  

	1.	Unless an Investor gives other instructions in writing to the Company, all payments to be made to the respective Investor under this Agreement shall exclusively be made by money transfer in Euros to an account of the
respective Investor submitted to the Company in writing. 

  

	2.	In the case the Company makes payments to the Investors, it is obliged to treat the Investors equally. Therefore, all payments to the Investors have to be made at the same time and pro rata their Loan Amounts.

  

	3.	As far as the Company makes payments to the Investors disregarding the regulation under para. (2) of this Sec. 6, the Investors undertake vis-à-vis each other to compensate each other for such deviating
payment to the ex-tent the aggrieved Investor would have received payments if the Company had considered the regulations under para. (2) of this Sec. 6. 

Sec. 7. 
 Taxes and
Duties 
 All payments by the Company to be made to the Investors under this Agreement shall be made without a discount or deduction of
any existent or future taxes or duties of whatever kind raised in the Federal Republic of Germany, unless the Company is obliged to withhold or deduct such taxes or duties by law. 

  

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 Sec. 8. 

Qualified Subordination 
  

	1.	The Parties herewith agree that claims for repayment of the Loan Amounts (including interest, costs and any other accessory claim, if any) (the “Claims”) shall be irrevocably subordinated
to any and all other liabilities, with the exception of those ranking pari passu, of the Company vis-à-vis its current or future creditors and therefore do not have to be settled, as long as and to the extent that the Company is insolvent or
over-indebted or was to be qualified as insolvent or over-indebted pursuant to §§ 17, 19 German Insolvency Code (Insolvenzordnung), would the Claims not be subordinated, or would an insolvency or over-indebtedness of the Company
exist for any other reason. This subordination also applies to the final distribution of liquidation proceeds pursuant to § 199 German Insolvency Code in the event of an insolvency proceeding (Insolvenzverfahren). Repayments of the Loan
Amounts shall only be made from future annual net income, net income from winding up or from other free assets (sonstiges freies Vermögen) of the Company. To the extent the Claims are subordinated, the Claims are ranked behind claims
pursuant to § 39 para. 1 no. 5 German Insolvency Code (Insolvenzordnung). 

  

	2.	If German jurisprudence should require further requirements for a qualified subordination agreement to be apt to avoid insolvency or over-indebtedness under German Insolvency Law, the Claims of the Holder shall be
regarded as having such rank as required in particular pursuant to German jurisprudence in order to avoid the passivation as liability in an over-indebtedness balance sheet (Überschuldungsbilanz) of the Company. 

Sec. 9. 
 Conversion
request 
  

	1.	The Investors are entitled but not obliged to request the conversion, in whole or in part, of the Loan Amounts into series B shares of the Company at the Series B Conversion Price (as defined in Sec. 11 of this
Agreement) at any time after the Maturity Date if and to the extent the Loan Amounts have not been repaid on or before the Maturity Date. 

  

	2.	Upon the occurrence of an Exit Event prior to the Maturity Date, the Investors are entitled but not obliged to request the conversion, in whole or in part, of the Loan Amounts into series B shares at the Series B
Conversion Price if and to the extent the Loan Amounts have not been repaid. 

  

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	3.	Upon the closing of a Qualified Financing, the Investors are entitled but not obliged to request the conversion, in whole or in part, of the Loan Amounts into the preferred stock of the Company, whether this is series B
or any other series of preferred stock, which is issued to new investors in a Qualified Financing (the “Qualified Financing Shares”) at the Qualified Financing Conversion Price (as defined in Sec. 11 of this Agreement) if and to the
extent the Loan Amounts have not been repaid. 

  

	4.	The Investors may request the conversion of the Loan Amounts according to para. (2) and (3) of this Sec. 9 at any time during a period of four (4) weeks after the occurrence of the Exit Event or closing
of the Qualified Financing, respectively. 

 Sec. 10. 

Conversion 
  

	1.	In order to request conversion of the Loan Amounts pursuant to Sec. 9 of this Agreement, the Investors shall submit to the Company a notice of conversion, in whole or in part, of the Loan Amounts (using the form
enclosed in Exhibit C) (the “Conversion Notice”). 

  

	2.	In the event that the Company receives a Conversion Notice, the Company shall invite all Shareholders, with the exception of the persons listed as indirect shareholders in Exhibit A, to a
shareholders’ meeting to be held within three months after receipt of the Conversion Notice by the Company, and all Shareholders undertake to vote their shares in such a shareholders’ meeting, to pass all resolutions required (including
but not limited to resolutions on a capital increase required to issue the New Shares as defined below (the “Capital Increase”) and necessary amendments to the Company’s Articles of Association) to issue the
respective number of new series B shares or Qualified Financing Shares, respectively (the “New Shares”), to be calculated according to Sec. 11 of this Agreement, to the Investors. The New Shares shall each be in
registered form, and shall be issued as non-par value shares with a portion of the Company’s share capital (anteiliger Betrag des Grundkapitals) of EUR 1.00 each, and shall be issued at an issue price (Ausgabebetrag) of EUR
1.00 per share without any premium. The New Shares shall have the right to participate in profits as from January 1, 2012. 

  

	3.	 Each Shareholder undertakes individually for himself vis-à-vis each other party, to do or cause to be done everything necessary to implement
the conversion request. Thus, the Shareholders undertake in particular to co-operate in the Capital Increase of the Company and in necessary amendments to the 

  

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Company’s Articles of Association by exercising their voting rights in the shareholders’ meeting of the Company, by subscribing to the New Shares as provided in this Agreement and by
waiving subscriptions rights to new shares in the Company if required to implement the conversion request. 

  

	4.	To the extent legally permitted, the Company and Shareholders shall secure that (i) the Company’s Management Board and the Supervisory Board will execute the Capital Increase, and (ii) the Company will
(a) accept the subscription of New Shares as described above, as well as (b) without undue delay apply for registration and of the consummation of the capital increase with the commercial register. 

 

	5.	The Investors shall pay in full their respective part of the cash contribution (EUR 1.00 per share) within ten (10) bank working days in Frankfurt/Main, Germany, after such Investor has subscribed for New
Shares to the Company’s special account to be named by the Company. Payments shall be made exclusively to this special account, which will be opened solely for this purpose and must not be used for other transactions or payments prior to the
aforementioned payments. This special account must not have a debit balance immediately prior to the aforementioned payments being effected, so that the Company’s Management Board can freely dispose of the amounts paid (cf. Sec. 188, 36, 36a,
37 German Act on Stock Corporations; “AktG”). 

  

	6.	In the event that the Investors request the conversion, in whole or in part, of the Loan Amounts in accordance with Sec. 9 para. (1), (2) or (3) of this Agreement and subscribe for the New Shares, each
Investor shall contribute (einlegen) without consideration his claim for repayment of the respective Loan Amount into the Company’s capital reserves pursuant to § 272 para. (2) No. 4 German Commercial Code
(Handelsgesetzbuch). The aforementioned contribution will be made subject to the implementation (Durchfúhrung) of the Capital Increase, i.e. the effective issue of the respective New Shares to such Investor. For clarification
purposes: the Company itself shall not be entitled to demand the contribution pursuant to this para. (6). Alternatively to the aforementioned contribution of the claim for repayment, the Investors may elect to waive their claims for repayment
vis-à-vis the Company. In this case, sentences 2 and 3 of this para. (6) shall apply accordingly. 

  

–    9 / 25 – 

 Sec. 11. 

Number of new Shares 
  

	1.	The number of New Shares to be issued in the course of the conversion in accordance with Sec. 9 para. (1) and (2) of this Agreement to each Investor shall be determined by the Loan Amount, to the extent that
has been paid out, divided by the “Series B Conversion Price”, which is to be calculated as follows: 

Series B Conversion Price = 

EUR 53 divided by [1 + (0.01 * M + 0.015 * N)], 

whereby M is the number of full months (rounded off) from the payment of the Loan Amounts to the Company until the earlier of the
(i) Maturity Date, or, (ii) the closing of a Qualified Financing or an Exit Event and 
 whereby N is the number of full months
(rounded off) from the payment of the Loan Amounts to the Company until Conversion less M. 
  

	2.	The number of Qualified Financing Shares with a nominal value of EUR 1.00 each to be issued in the course of the conversion in accordance with Sec. 9 para. (3) of this Agreement to each Investor shall be determined
by the Loan Amount, to the extent that has been paid out, divided by the “Qualified Financing Conversion Price”, which is to be calculated as follows: 

Qualified Financing Conversion Price = 

the price per share of preferred stock of the Company issued to investors in a Qualified Financing less a discount of twenty percent
(20%) divided by [1 + (0.01 * M + 0.015 * N)] 
 whereby M and N have the meaning as defined in para. (1) of this Sec. 11. 

 

	3.	If the Loan Amount of an Investor exceeds the portion of the loan attributable to such an Investor pro rata its shareholding in the shares of the Company, the number of New Shares into which the exceeding amount is
converted in accordance with this Sec. 11 shall be multiplied by the factor 1.2, the result being rounded down to the nearest whole number. 

  

	4.	Residual amounts of the respective Loan Amounts that are indivisible after application of para (1) and (2) of this Sec. 11 are awarded to such Investor who has the highest Loan Amount and will increase his
Loan Amount which is subject to conversion in accordance with para (1) and (2) of this Sec. 11, the result being rounded down to the nearest whole number. 

  

–    10 / 25 – 

 Sec. 12. 

Lapse of the Conversion Right 
  

	1.	The right of the Investors to request conversion pursuant to Sec. 9 of this Agreement lapses provided that 

  

	 	a.	the Company is converted to a different or into another legal entity within the meaning of the German Act on Transformations (Umwandlungsgesetz), and 

 

	 	b.	the Investors are compensated with (i) conversion rights to shares of the new legal entity, or (ii) shares of the new legal entity, each of equal value. 

 

	2.	Shares or respectively conversion rights in the new legal entity are considered as having equal value, if their value is equivalent to the value of the conversion rights of the Company on the point in time of the
effectiveness of the conversion. 

  

	3.	The valuation of these conversion rights / shares will be undertaken by the auditor of the conversion or, if an audit within the conversion is not mandatory by law, by a business valuator to be instructed by the Company
and the Investors. 

 Sec. 13. 

Exercise of Investor Rights 
  

	1.	Investor rights, including but not limited to the conversion of the Convertible Bridge Loan, may only be exercised jointly by the Investors and upon demand of Investors whose aggregated Loan Amounts exceed 50% of the
total Loan Amounts (“Investor Majority”), unless specified differently in this Agreement. 

  

	2.	Each Investor shall exercise his rights in accordance with the decision of the Investor Majority and shall procure to take all measures required to not block or prevent such decision of the Investor Majority and its
implementation. 

 Sec. 14. 

Expenses 
 The Company shall
pay the Investors’ reasonable due diligence and legal expenses (including VAT, if applicable), limited to an aggregate amount of EUR 6,500.00 for all Investors, subject to the Convertible Bridge Loan being paid out. 

  

–    11 / 25 – 

 Sec. 15. 

Final Provisions 
  

	1.	Each of the Shareholders shall be entitled to transfer its rights and obligations under this Agreement together with the shares to which such rights and obligations relate in whole or in part, provided that such
Shareholder may transfer his shares under the CSA 2012. 

  

	2.	Each of the Shareholders undertakes individually for himself vis-à-vis each other Shareholder, to impose on his individual legal successors, if any, the rights and obligations arising under this Agreement in such
a way, that his individual legal successors are bound by the rights and obligations under this Agreement as if they had themselves undertaken these rights and obligations. This shall also apply to the obligation undertaken in this para. 2 to impose
the rights and obligations under this Agreement on any individual legal successors. 

  

	3.	The Shareholders are entitled to the rights under this Agreement to the exclusion of any joint entitlement, i.e. in such a way that each of the Share-holders may individually exercise the rights to which they are
entitled, unless otherwise expressly provided in this Agreement. Joint and several liability (gesamtschuldnerische Hartung) of the Shareholders — including but not limited to the payment of the Loan Amounts to the Company — shall be
excluded. 

  

	4.	Amendments and additions to this Agreement must be made in writing to be effective unless notarization is required. This shall also apply to a waiver of the written form requirement. Signatures transmitted by way of
facsimile communication shall satisfy the written form requirement. 

  

	5.	Should individual terms of this Agreement be or become invalid or unenforceable or if this Agreement contains gaps, this shall not affect the validity of the remaining terms of this Agreement or the CSA 2012. In place
of the invalid, unenforceable or missing term, such valid term which the parties would reasonably have agreed, had they been aware at the conclusion of this Agreement that the relevant term was invalid, unenforceable or missing, shall be deemed to
have been agreed. Should a term of this Agreement be or become invalid because of the scope or time of performance for which it provides, then the agreed scope or time of performance shall be amended to correspond with the extent legally permitted.

  

	6.	The Parties shall keep strictly confidential the fact that they have entered into negotiations regarding the transactions contemplated in this Agreement and the contents of such negotiations and the contents of this
Agreement, except if and to the extent that disclosure is required by law or stock exchange regulations and the other parties have been notified of such requirement. This Agreement, however, may be shared with the existing shareholders and potential
outside investors. Furthermore, the Parties are permitted to share such information with the persons/entities/bodies mentioned in Sec. 22 para. (2) sentence 2 of the CSA 2012. In particular, Technologie Beteiligungsfonds II Bayern
GmbH & Co. KG and KfW shall be allowed to disclose their participations in the Company vis-à-vis the Bavarian Supreme Auditing Agency (Bayerischer Oberster Rechnungshot), the Federal Supervisory Agency
(Bundesrechungshof) and the Federal Department of Economics (Bundeswirtschaftsministerium) as required by applicable law. 

  

–    12 / 25 – 

	7.	Prior to any announcement, the Company and the Investors shall agree upon the form and contents of any press release with respect to this Convertible Bridge Loan. 

 

	8.	With regard to the signing of the Agreement, signatures transmitted by way of facsimile communication shall suffice and be binding. Reception of an original copy of this Agreement signed by all Parties is not a
condition for the validity of this Agreement. 

  

	9.	This Agreement is governed by and shall be construed in accordance with the laws of Germany, without regard to its provisions of private international law and excluding the UN Sales Convention. 

 

	10.	To the extent legally permissible, place of venue and performance shall be Munich. All disputes arising in connection with this Agreement shall be finally settled in accordance with the Arbitration Rules of the German
Institution of Arbitration e.V. (DIS) without recourse to the ordinary courts of law and according to the Arbitration Agreement enclosed as Exhibit 15.10. This shall include disputes regarding the validity, the performance or the termination
of this Investment Agreement in whole or in part including possible amendments of the same. The place of arbitration is Munich. The arbitration tribunal consists of three arbitrators. The language of the arbitration proceeding is English.

  

	11.	The Exhibits to this Agreement are an essential part of it. The headings in this Agreement only serve for a better orientation and are of no significance for the content and interpretation of this Agreement.
Explanations in a provision or Exhibit to this Agreement are also deemed to be listed for purposes of all other provisions or Exhibits. 

  

	12.	German definitions in this document shall take precedence over the respective English terms. 

  

–    13 / 25 – 

 Freising, this 12th of November, 2012 

 

					
	 /s/ Claus Schalper
	 		 	 /s/ Hans Küpper

	 PIERIS AG

signed for and on behalf of the Management Board
	 		 	 PIERIS AG

signed for and on behalf of the supervisory Board

			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	Orbimed Private Investments III, LP	 		 	Orbimed Associates III, LLC
			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	Novo Nordisk A/S	 		 	Transconnect Corporate Finance Beratungs GmbH
			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	BioM AG	 		 	BioM Venture Capital GmbH & Co. KG
			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	The Global Life Science Ventures Fonds II GmbH & Co. KG	 		 	The Global Life Science Ventures Fund II LP
			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	Gilde Europe & Agribusiness Fund B.V.	 		 	Baytech Venture Capital GmbH & Co. KG
			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	Coöperative AAC LS U.A.	 		 	KfW
			
	 /s/ Authorized Signatory
	 		 	 /s/ Arne Skerra

	Technologie Beteiligungsfonds II Byern GmbH & Co. KG (Byern Kapital)	 		 	Prof. Skerra Bet. GmbH

  

–    14 / 25 – 

					
	 /s/ Steffen Schlehuber
	 		 	 /s/ Claus Schalper

	Dr. Steffen Schlehuber	 		 	Claus Schalper
			
	 /s/ Karsten Schürrie
	 		 	 /s/ Martin Pöhlchen

	Dr. Karsten Schürrie	 		 	MAPO Bet. GmbH
			
	 /s/ Arne Skerra
	 		 	 /s/ Martin Pöhlchen

	Prof. Dr. Arne Skerra	 		 	Dr. Martin Pöhlchen

  

–    15 / 25 – 

 Table of Annexes to the Convertible Bridge Loan Agreement 

 

			
	Exhibit A:	  	List of Holders of Common Shares, of Preferred Shares Series A, of Preferred Shares Series A-1, of Preferred Shares Series B and of Indirect Shareholders
		
	Exhibit B:	  	Consolidated Shareholders’ Agreement 2012 dated November 12, 2012
		
	Exhibit C:	  	Conversion Notice
		
	Exhibit 15.10	  	Arbitration Agreement

  

–    16 / 25 – 

 Exhibit A: 

List of Holders of Common Shares, of Preferred Shares Series A, of Preferred Shares Series A-1, of Preferred Shares Series B and of Indirect Shareholders

  

			
	 Name
	  	 Participation as

	Prof. Skerra Beteiligungsgesellschaft mbH, Max Lehner-Straße 19, 85354 Freising, Germany	  	Holder of Common Shares
		
	Dr. Steffen Schlehuber, In den Kappesgärten 22, 67152 Ruppertsberg, Germany	  	Holder of Common Shares
		
	Claus Schalper, Ismaningerstraße 62,81675 Munich, Germany	  	Holder of Common Shares
		
	Dr. Karsten Schürrle, Palmstraße 7,60316 Frankfurt a.M., Germany	  	Holder of Common Shares
		
	MAPO Beteiligungsgesellschaft mbH, Hubertusweg 34, 85540 Haar, Germany	  	Holder of Common Shares
		
	BioM Aktiengesellschaft Munich, BioTech Development, Am Klopferspitz 19,82152 Planegg, Germany	  	 Holder of Common Shares
  

Holder of Preferred Shares Series B

		
	BioM Venture Capital GmbH & Fonds KG, Am Klopferspitz 19, 82152 Planegg, Germany	  	 Holder of Common Shares
  

Holder of Preferred Shares Series A
  

Holder of Preferred Shares Series A-1
  

Holder of Preferred Shares Series B

		
	Transconnect Corporate Finance Beratungs GmbH, Prinzregentenstraße 56, 80538 Munich, Germany	  	 Holder of Common Shares
  

Holder of Preferred Shares Series A
  

Holder of Preferred Shares Series A-1
  

Holder of Preferred Shares Series B

  

–    17 / 25 – 

			
	The Global Life Science Ventures Fonds II GmbH & Co. KG, Von-der-Tann-Straße 3, 80539 Munich, Germany	  	 Holder of Preferred Shares Series A
  

Holder of Preferred Shares Series A-1
  

Holder of Preferred Shares Series B

		
	The Global Life Science Ventures Fund II Limited Partnership, PO Box 431, Alexander House,13-15 Victoria Road, St. Peter Port, Guernsey, G41 3ZD	  	 Holder of Preferred Shares Series A
  

Holder of Preferred Shares Series A-1
  

Holder of Preferred Shares Series B

		
	Gilde Europe Food & Agribusiness Fund B.V., Newtonlaan 91, 3584 BP Utrecht, The Netherlands	  	 Holder of Preferred Shares Series A
  

Holder of Preferred Shares Series A-1
  

Holder of Preferred Shares Series B

		
	BayTech Venture Capital GmbH & Co. KG, Theatinerstraße 7, 80353 Munich, Germany	  	 Holder of Preferred Shares Series A
  

Holder of Preferred Shares Series A-1
  

Holder of Preferred Shares Series B

		
	Coöoperatieve AAC LS U.A., Gooimeer 2-35, P.O. Box 5187, 1410 AD Naarden, The Netherlands	  	 Holder of Preferred Shares Series A
  

Holder of Preferred Shares Series A-1
  

Holder of Preferred Shares Series B

  

–    18 / 25 – 

			
	KfW, Ludwig-Erhard-Platz 1-3, 53179 Bonn	  	 Holder of Preferred Shares Series A-1
  

Holder of Preferred Shares Series B

		
	Technologie Beteiligungsfonds Bayern II GmbH & Co. KG, Altstadt 72, 84028 Landshut, (BayernKapital)	  	 Holder of Preferred Shares Series A-1
  

Holder of Preferred Shares Series B

		
	Orbimed Private Investments III, LP, 601 Lexington Ave, Floor 54, New York, NY 10022, USA	  	Holder of Preferred Shares Series B
		
	Orbimed Associates III, LLC, 601 Lexington Ave, Floor 54, New York, NY 10022, USA	  	Holder of Preferred Shares Series B
		
	Novo Nordisk A/S, Novo Allé, 2880 Bagsvrd, Denmark	  	Holder of Preferred Shares Series B
		
	Prof. Dr. Arne Skerra, Max-Lehner-Straße 19, 85354 Freising, Germany	  	Indirect Shareholder
		
	Dr. Martin Pohlchen, Hubertusweg 34, 85540 Haar, Germany	  	Indirect Shareholder

  

–    19 / 25 – 

 Exhibit B 

  

–    20 / 25 – 

 Exhibit C: 

Conversion Notice 
 To: 

PIERIS AG 
 Management Board 

Lise-Meitner-Str. 30 
 85354 Freising 

Germany 
 We, the Investors as listed in Sec. 1 para. (2) of
the Convertible Bridge Loan Agreement dated November 12, 2012 (the “Convertible Bridge Loan Agreement”), have granted PIERIS AG, a company registered in the commercial register of the local court of Munich under No. HRB 133223
(the “Company”), a convertible bridge loan in the total amount of EUR 2,000,000 (the “Convertible Bridge Loan”), in accordance with the Convertible Bridge Loan Agreement. 

In relation to the Convertible Bridge Loan, the amount of 

EUR             

has not been repaid by the Company to the Investors (the “Remaining Loan Amount”) as of the date of this Conversion Notice. 

Based on the foregoing, we hereby request conversion 
  

	 	 ̈	of the whole Remaining Loan Amount 

  

	 	 ̈	of EUR          of the Remaining Loan Amount 

 pursuant to 

 

	 	 ̈	Sec. 9 para. (1) of the Convertible Bridge Loan Agreement (after the Maturity Date) into series B shares of the Company. 

 

	 	 ̈	Sec. 9 para. (2) of the Convertible Bridge Loan Agreement (occurrence of an Exit Event prior to the Maturity Date) into series B shares of the Company. 

 

	 	 ̈	Sec. 9 para. (3) of the Convertible Bridge Loan Agreement (closing of a Qualified Financing) into Qualified Financing Shares. 

Conversion shall be effected in accordance with the provisions of the Convertible Bridge Loan Agreement at the price and on the terms set out in the
Convertible Bridge Loan Agreement. 
 All terms used herein shall have the meaning as given to them in the Convertible Bridge Loan Agreement. 

  

–    21 / 25 – 

 With regard to the signing of this Conversion Notice, signatures transmitted by way of facsimile communication
shall suffice and be binding. 
 Freising,
            ,         
  

					
	  
	 		 	  

	Orbimed Private Investments III, LP	 		 	Orbimed Associates III, LLC
			
	  
	 		 	  

	Novo Nordisk A/S	 		 	Transconnect Corporate Finance Beratungs GmbH
			
	  
	 		 	  

	BioM AG	 		 	BioM Venture Capital GmbH & Co. KG
			
	  
	 		 	  

	The Global Life Science Ventures Fonds II GmbH & Co. KG	 		 	The Global Life Science Ventures Fund II LP
			
	  
	 		 	  

	Gilde Europe & Agribusiness Fund B.V.	 		 	Baytech Venture Capital GmbH & Co. KG
			
	  
	 		 	  

	Coöperative AAC LS U.A.	 		 	KfW

  

–    22 / 25 – 

					
	  
	 		 	
	Technologie Beteiligungsfonds II Byern GmbH & Co. KG (Byern Kapital)	 		 	

  

–    23 / 25 – 

 Exhibit 15.10 

Arbitration Agreement 
  

	1	With regard to all disputes arising out of the Convertible Bridge Loan Agreement and Consolidated Shareholders’ Agreement of Pieris AG, Lise-Meitner-Strasse 30, 85354 Freising, the Parties agree on the following
arbitration clause: 

  

	2.	Place of venue and performance shall, to the extent legally permissible, be Munich. All disputes arising in connection with the Convertible Bridge Loan and the Consolidated Shareholders’ Agreement shall be finally
settled in accordance with the Arbitration Rules of the German Institution of Arbitration e.V. (DIS) without recourse to the ordinary courts of law. This shall include disputes regarding the validity, the performance or the termination of the
Convertible Bridge Loan and the Consolidated Shareholders’ Agreement in whole or in part including possible amendments of the same. The place of arbitration is Munich. The arbitral tribunal consists of three arbitrators. The language of the
arbitral proceedings is English. 

 Freising, November 12, 2012 

 

					
	 /s/ Claus Schalper
	 		 	 /s/ Hans Küpper

	 PIERIS AG

signed for and on behalf of the Management Board
	 		 	 PIERIS AG

signed for and on behalf of the supervisory Board

			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	Orbimed Private Investments III, LP	 		 	Orbimed Associates III, LLC
			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	Novo Nordisk A/S	 		 	Transconnect Corporate Finance Beratungs GmbH
			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	BioM AG	 		 	BioM Venture Capital GmbH & Co. KG
			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	The Global Life Science Ventures Fonds II GmbH & Co. KG	 		 	The Global Life Science Ventures Fund II LP
			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	Gilde Europe & Agribusiness Fund B.V.	 		 	Baytech Venture Capital GmbH & Co. KG
			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	Coöperative AAC LS U.A.	 		 	KfW
			
	 /s/ Authorized Signatory
	 		 	 /s/ Arne Skerra

	Technologie Beteiligungsfonds II Byern GmbH & Co. KG (Byern Kapital)	 		 	Prof. Skerra Bet. GmbH

  

–    24 / 25 – 

					
	 /s/ Steffen Schlehuber
	 		 	 /s/ Claus Schalper

	Dr. Steffen Schlehuber	 		 	Claus Schalper
			
	 /s/ Karsten Schürrie
	 		 	 /s/ Martin Pöhlchen

	Dr. Karsten Schürrie	 		 	MAPO Bet. GmbH
			
	 /s/ Arne Skerra
	 		 	 /s/ Martin Pöhlchen

	Prof. Dr. Arne Skerra	 		 	Dr. Martin Pöhlchen

  

–    25 / 25 –EX-10.25

 Exhibit 10.25 

Amendment to the 

Convertible Bridge Loan Agreement 

dated November 12, 2012 

between 
  

	1.	Pieris AG, Lise-Meitner-Str. 30, 85354 Freising, Germany (the “Company”), represented by its management board, consisting of Stephen S. Yoder, and its supervisory board, being represented by its
chairman, Dr. Hans A. Küpper, 

  

	2.	Orbimed Private Investments Ill, LP, 

  

	3.	Orbimed Associates Ill, LLC, 

  

	4.	Novo Nordisk A/S, 

  

	5.	Transconnect Corporate Finance Beratungs GmbH, 

  

	6.	BioM AG, 

  

	7.	BioM Venture Capital GmbH & Co. KG, 

  

	8.	The Global Life Science Ventures Fonds II GmbH & Co. KG, 

  

	9.	The Global Life Science Ventures Fund II LP, 

  

	10.	Gilde Europe Food & Agribusiness Fund B.V, 

  

	11.	Baytech Venture Capital GmbH & Co. KG, 

  

	12.	Coöperatieve AAC LS U.A., 

  

	13.	KfW, 

  

	14.	Technologie Beteiligungsfonds II Bayern GmbH & Co. KG (BayernKapital), 

  

	15.	Prof. Skerra Bet. GmbH, 

  

	16.	Dr. Steffen Schlehuber, 

  

	17.	Claus Schalper, 

  

	18.	Dr. Karsten Schürrle, 

  

	19.	MAPO Bet. GmbH, 

  

	20.	Prof. Dr. Arne Skerra and 

  

	21.	Dr. Martin Pöhlchen 

 The persons or entities set out in (2) – (21) shall be
jointly referred to as the “Shareholders” and the Shareholders together with the Company shall be jointly referred to as the “Parties”. 

 Preamble 
  

	1.	On November 12, 2012 the Parties entered into a convertible bridge loan agreement (the “Convertible Bridge Loan Agreement”) pursuant to which certain Shareholders, which are listed as Investors in
the table in Sec. 1 (Convertible Bridge Loan) para. 2 of the Convertible Bridge Loan Agreement with a loan amount in EUR other than 0 (zero) (the “Holders”), made available to the Company a bridge loan in the amount of EUR
2,000,000, which loan is convertible into shares of the Company (the “Convertible Bridge Loan”). 

  

	2.	The Parties have decided (i) that the Company shall repay a EUR amount equal to USD 400,000 of the Convertible Bridge Loan to the Holders (the “Repayment Amount”) and (ii) to postpone the
maturity date of the remaining loan amount of the Convertible Bridge Loan, which date was December 31, 2013 to December 31, 2015 (the “New Maturity Date”). 

 

	3.	It is intended by the Parties that all of the Company’s shares, irrespective of their liquidation preference, will be contributed (eingebracht) by the Shareholders into a U.S. shell company (the
“Shell Company”), which is to be listed on a stock exchange (e.g. first on OTC Bulletin and, subsequently, on NASDAQ), or into a subsidiary of such Shell Company, against issuance of shares of common stock in the Shell Company to
the Shareholders (the “Reverse Merger”). The Company has identified Zosano, Inc., a Delaware corporation, as the Shell Company. The Holders desire to instruct the Company to pay the Repayment Amount to the Shell Company and/or its
shareholders in order to ensure that all necessary corporate actions are taken by the Shell Company and/or its shareholders in connection with the intended Reverse Merger. In addition, the Parties intend to make other arrangements relating to the
Convertible Bridge Loan Agreement in connection with the Reverse Merger. 

 NOW, THEREFORE the Parties hereby enter into the following
Amendment to the Convertible Bridge Loan Agreement (this “Amendment Agreement”) and agree as follows: 

  
 – 2 / 9 – 

 Sec. 1 

Repayment Amount 
  

	1.	In deviation from the provisions of the Convertible Bridge Loan Agreement governing repayment of the Convertible Bridge Loan, the Company shall repay the Repayment Amount to the Holders at the time as necessary to
observe the instructions of the Holders set out in Sec. 2 (Instructions of the Holders; Compensation Payments) para. 1 and in accordance with the following table: 

 

					
	 Investor
	  	Repayment Amount in USD	 
	 Orbimed Private Investments III, LP
	  	 	98,423.00	  
	 Orbimed Associates III, LLC
	  	 	937.00	  
	 Novo Nordisk A/S
	  	 	39,921.00	  
	 Transconnect Corporate Finance Beratungs GmbH
	  	 	10,057.00	  
	 BioM AG
	  	 	32,950.00	  
	 The Global Life Science Ventures Fonds II GmbH & Co. KG
	  	 	50,435.00	  
	 The Global Life Science Ventures Fund II LP
	  	 	39,229.00	  
	 Gilde Europe Food & Agribusiness Fund B.V.
	  	 	84,203.00	  
	 Coöperatieve AAC LS U.A.
	  	 	43,845.00	  
		  	  
	  
	 
	 Total
	  	 	400,000.00	  
		  	  
	  
	 

  

	2.	The part of the Repayment Amount in USD displayed in the table above for each Holder (the “Repayment Portion”) shall be paid to the respective Holder in the corresponding EUR amount. 

 

	3.	The outstanding principal amount of the Convertible Bridge Loan will be reduced accordingly (i.e. by the Repayment Amount). 

  

	4.	If less than the entire Repayment Amount is required to fulfil the instructions of the Holders under Sec. 2 (Instructions of the Holders; Compensation Payments) para. 1, the Repayment Amount shall be reduced
accordingly and the Repayment Portions shall be adjusted proportionately. The Repayment Amount may be paid in partial payments if it is required to observe the instructions of the Holders under Sec. 2 (Instructions of the Holders; Compensation
Payments) para. 1. 

  

	5.	The interest on the Repayment Amount shall be due and payable upon repayment of the principal amount of the Convertible Bridge Loan remaining after payment of the Repayment Amount. 

Sec. 2 
 Instructions of
the Holders; Compensation Payments 
  

	1.	 The Holders hereby irrevocably instruct the Company to pay the Repayment Amount on their behalf to the identified Shell Company and/or its
shareholders, in order to ensure all necessary corporate actions and other measures in connection with the intended Reverse Merger are taken 

  
 – 3 / 9 – 

	 	
by the Shell Company and/or its shareholders under the terms of a term sheet agreed between the Company and the Shell Company and in accordance with the agreements related to the Reverse Merger
when such agreements are concluded. The Holders and the Company are in agreement that (i) the deposit in the amount of USD 50,000 made by the Company under the Term Sheet of March 2013 agreed between the Company and Zosano, Inc. shall be deemed
to have been paid for the purpose set out above; and (ii) once the remaining Repayment Amount is paid to the Shell Company and/or its shareholders, the Repayment Amount shall be deemed to have been paid in whole by the Holders.

  

	2.	Those of the Shareholders who did not participate in the Convertible Bridge Loan or participated with a loan amount which was less than their pro rata share, based on their current shareholding in the Company, of the
Convertible Bridge Loan (the “Compensating Shareholders”) shall make compensation payments (the “Compensation Payments”) to those of the Holders whose Repayment Portion exceeds their respective pro rata share, based
on their current shareholding in the Company, of the Repayment Amount. The Compensation Payments shall put all Shareholders in a position as if the Repayment Amount (paid to the Shell Company on behalf of the Holders for the purpose set out in
para.1 of this Sec. 2) had been divided among all Shareholders pro rata to each Shareholder’s current shareholding in the Company. 

  

	3.	The Company will calculate the Compensation Payments once the entire Repayment Amount has been paid or when it has determined that any remaining part of the Repayment Amount is not required and will inform the
Compensating Shareholders and Holders accordingly. Compensation Payments shall then be made by Compensating Shareholders within one (1) week to the Company and the Company will forward the Compensation Payments on behalf of the Compensating
Shareholders to the respective Holders. 

 Sec. 3 

Postponement of Maturity Date 

Sec. 3 (Term) of the Convertible Bridge Loan Agreement is amended to read as follows: 

“The Convertible Bridge Loan is granted until December 31, 2015.” 

Sec. 4 
 Lapse of
Conversion Rights; Repayment Right 
 In the event that the contribution (Einbringung) of the Company’s shares into the Shell Company or
into a subsidiary of such Shell Company, as the case may be, against issuance of shares in the Shell Company to the Shareholders in the course of the intended Reverse Merger becomes effective, 

 

	(i)	the conversion rights of the Investors (as defined in the Convertible Bridge Loan Agreement) under Sec. 9 et seqq. of the Convertible Bridge Loan Agreement shall lapse; and 

 

	(ii)	the Company shall, in deviation from the provisions of the Convertible Bridge Loan Agreement governing repayment of the Convertible Bridge Loan, be entitled to repay the remaining outstanding amount of the Convertible
Bridge Loan (after the payment of the Repayment Amount) and the interest thereon, as well as the interest on the Repayment Amount, before the New Maturity Date, in accordance with a payment schedule to be notified by the Company to the Holders.

  
 – 4 / 9 – 

 Sec. 5 

Miscellaneous 
  

	1.	All provisions of the Convertible Bridge Loan Agreement not expressly amended by this Amendment Agreement shall remain unaffected. 

  

	2.	For the avoidance of doubt: All rights and obligations of the Parties under the Convertible Bridge Loan Agreement which are dependent on or refer to “the Maturity Date” shall, upon execution of this Amendment
Agreement, depend on or refer to the New Maturity Date. 

  

	3.	Amendments and additions to this Amendment Agreement must be made in writing to be effective unless notarization is required. This shall also apply to a waiver of the written form requirement. Signatures transmitted by
way of facsimile communication shall satisfy the written form requirement. 

  

	4.	Should individual terms of this Amendment Agreement be or become invalid or unenforceable or if this Agreement contains gaps, this shall not affect the validity of the remaining terms of this Amendment Agreement or the
Convertible Bridge Loan Agreement. In place of the invalid, unenforceable or missing term, such valid term which the parties would reasonably have agreed, had they been aware at the conclusion of this Amendment Agreement that the relevant term was
invalid, unenforceable or missing, shall be deemed to have been agreed. Should a term of this Amendment Agreement be or become invalid because of the scope or time of performance for which it provides, then the agreed scope or time of performance
shall be amended to correspond with the extent legally permitted. 

  

	5.	With regard to the signing of this Amendment Agreement, signatures transmitted by way of facsimile communication shall suffice and be binding. Reception of an original copy of this Amendment Agreement signed by all
Parties is not a condition for the validity of this Amendment Agreement. 

  

	6.	This Amendment Agreement is governed by and shall be construed in accordance with the laws of Germany, without regard to its provisions of private international law and excluding the UN Sales Convention.

  

	7.	To the extent legally permissible, place of venue and performance shall be Munich. All disputes arising in connection with this Amendment Agreement shall be finally settled in accordance with the Arbitration Rules of
the German Institution of Arbitration e.V. (DIS) without recourse to the ordinary courts of law and according to the Arbitration Agreement enclosed as Exhibit 1. This shall include disputes regarding the validity, the performance or the
termination of this Amendment Agreement in whole or in part including possible amendments of the same. The place of arbitration is Munich. The arbitration tribunal consists of three arbitrators. The language of the arbitration proceeding is English.

  
 – 5 / 9 – 

 Freising, March 2014 
  

					
	 /s/ Stephen Yoder
	 		 	 /s/ Hans Küpper

	 PIERIS AG

Signed for and on behalf of the Management Board
	 		 	 PIERIS AG

Signed for and on behalf of the Supervisory Board

			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	Orbimed Private Investments III, LP	 		 	Orbimed Associates III, LLC
			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	Novo Nordisk A/S	 		 	Transconnect Corporate Finance Beratungs GmbH
			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	BioM AG	 		 	BioM Venture Capital GmbH & Co. KG
			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	The Global Life Science Ventures Fonds II GmbH & Co. KG	 		 	The Global Life Science Ventures Fund II LP
			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	Gilde Europe Food & Agribusiness Fund B.V.	 		 	Baytech Venture Capital GmbH & Co. KG
			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	Coöperatieve AAC LS U.A.	 		 	KfW
			
	 /s/ Authorized Signatory
	 		 	 /s/ Arne Skerra

	Technologie Beteiligungsfonds II Bayern GmbH & Co. KG (BayernKapital)	 		 	Prof. Skerra Bet. GmbH
			
	 /s/ Steffen Schlehuber
	 		 	 /s/ Claus Schalper

	Dr. Steffen Schlehuber	 		 	Claus Schalper

  
 – 6 / 9 – 

					
			
	 /s/ Karsten Schürrle
	 		 	 /s/ Martin Pöhlchen

	Dr. Karsten Schürrle	 		 	MAPO Bet. GmbH
			
	 /s/ Arne Skerra
	 		 	 /s/ Martin Pöhlchen

	Prof. Dr. Arne Skerra	 		 	Dr. Martin Pöhlchen

  
 – 7 / 9 – 

 Exhibit 1 

Arbitration Agreement 
  

	1.	With regard to all disputes arising out of this Amendment to the Convertible Bridge Loan Agreement dated November 12, 2012 of Pieris AG, Lise-Meitner-Strasse 30, 85354 Freising (this “Amendment
Agreement”), the Parties agree on the following arbitration clause: 

  

	2.	Place of venue and performance shall, to the extent legally permissible, be Munich. All disputes arising in connection with the Convertible Bridge Loan and the Consolidated Shareholders’ Agreement shall be finally
settled in accordance with the Arbitration Rules of the German Institution of Arbitration e.V. (DIS) without recourse to the ordinary courts of law. This shall apply in particular to disputes regarding the validity, the execution or the termination
of this Amendment Agreement, its individual provisions or possible amendments to it. The place of arbitration is Munich. The arbitral tribunal consists of three arbitrators. The language of the arbitral proceedings is English. 

Freising, March 2014 
  

					
	 /s/ Stephen Yoder
	 		 	 /s/ Hans Küpper

	 PIERIS AG

Signed for and on behalf of the Management Board
	 		 	 PIERIS AG

Signed for and on behalf of the Supervisory Board

			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	Orbimed Private Investments III, LP	 		 	Orbimed Associates III, LLC
			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	Novo Nordisk A/S	 		 	Transconnect Corporate Finance Beratungs GmbH
			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	BioM AG	 		 	BioM Venture Capital GmbH & Co. KG
			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	The Global Life Science Ventures Fonds II GmbH & Co. KG	 		 	The Global Life Science Ventures Fund II LP

  
 – 8 / 9 – 

					
			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	Gilde Europe Food & Agribusiness Fund B.V.	 		 	Baytech Venture Capital GmbH & Co. KG
			
	 /s/ Authorized Signatory
	 		 	 /s/ Authorized Signatory

	Coöperatieve AAC LS U.A.	 		 	KfW
			
	 /s/ Authorized Signatory
	 		 	 /s/ Arne Skerra

	Technologie Beteiligungsfonds II Bayern GmbH & Co. KG (BayernKapital)	 		 	Prof. Skerra Bet. GmbH
			
	 /s/ Steffen Schlehuber
	 		 	 /s/ Claus Schalper

	Dr. Steffen Schlehuber	 		 	Claus Schalper
			
	 /s/ Karsten Schürrle
	 		 	 /s/ Martin Pöhlchen

	Dr. Karsten Schürrle	 		 	MAPO Bet. GmbH
			
	 /s/ Arne Skerra
	 		 	 /s/ Martin Pöhlchen

	Prof. Dr. Arne Skerra	 		 	Dr. Martin Pöhlchen

  
 – 9 / 9 –

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