Document:

EX-4.1

 Exhibit 4.1 

Execution Version 
  

 
  

ING GROEP N.V., 
 Issuer 

and 
 THE BANK OF NEW YORK MELLON,
LONDON BRANCH, 
 Trustee 
  

 
 FOURTH
SUPPLEMENTAL INDENTURE 
 Dated as of September 14, 2021 
  

 
 To the Capital
Securities Indenture, dated as of April 16, 2015, 
 Between ING Groep N.V. 

and 
 The Bank of New York Mellon,
London Branch, Trustee 
 $1,000,000,000 3.875% Perpetual Additional Tier 1 Contingent Convertible Capital Securities 

$1,000,000,000 4.250% Perpetual Additional Tier 1 Contingent Convertible Capital Securities 

Amendments to the Capital Securities Indenture 
  

 
  

 ING GROEP N.V. 

Reconciliation and tie between Trust Indenture Act of 1939, as amended by the Trust Indenture Reform Act of 1990, and that certain Indenture (the
“Base Indenture”), dated as of April 16, 2015, as supplemented by this Fourth Supplemental Indenture (this “Fourth Supplemental Indenture”), dated as of September 14, 2021. 

 

					
	 Trust Indenture Act Section
	  	Indenture Section
	 §310
	 	 (a)(1)
	  	6.09
		 	 (a)(2)
	  	6.09
		 	 (a)(3)
	  	Not Applicable
		 	 (a)(4)
	  	Not Applicable
		 	 (b)
	  	6.08
 6.10

	 §311
	 	 (a)
	  	6.13
		 	 (b)
	  	6.13
	 §312
	 	 (a)
	  	7.01
 7.02(a)

		 	 (b)
	  	7.02(b)
		 	 (c)
	  	7.02(c)
	 §313
	 	 (a)
	  	7.03(a)
		 	 (b)
	  	7.03(a)
		 	 (c)
	  	1.06,7.03(a)
		 	 (d)
	  	7.03(b)
	 §314
	 	 (a)
	  	7.04, 10.06
		 	 (b)
	  	Not Applicable
		 	 (c)(1)
	  	1.02
		 	 (c)(2)
	  	1.02
		 	 (c)(3)
	  	Not Applicable
		 	 (d)
	  	Not Applicable
		 	 (e)
	  	1.02
		 	 (f)
	  	Not Applicable
	 §315
	 	 (a)
	  	6.01, 6.03
		 	 (b)
	  	6.02
		 	 (c)
	  	5.04, 6.01
		 	 (d)(1)
	  	6.01, 6.03
		 	 (d)(2)
	  	6.01, 6.03
		 	 (e)
	  	5.14
	 §316
	 	 (a)(1)(A)
	  	5.02, 5.12
		 	 (a)(1)(B)
	  	5.13
		 	 (a)(2)
	  	Not Applicable
		 	 (a)(last sentence)
	  	1.01
		 	 (b)
	  	5.08
	 §317
	 	 (a)(1)
	  	6.02 of Fourth Supplemental
Indenture
		 	 (a)(2)
	  	5.04
		 	 (b)
	  	10.03
	 §318
	 	 (a)
	  	1.07

 NOTE: This reconciliation and tie shall not, for any purpose, be deemed to be a part of this Fourth Supplemental Indenture or
the Base Indenture. Section references are to Base Indenture except as indicated. 

 TABLE OF CONTENTS 

 

							
	 	  	 	  	Page	 
	 	  	ARTICLE I	  	 	 
			
	 	  	DEFINITIONS AND OTHER PROVISIONS OF GENERAL APPLICATION	  	 	 
			
	 Section 1.01
	  	Definitions	  	 	1	 
	 Section 1.02
	  	Effect of Headings	  	 	9	 
	 Section 1.03
	  	Separability Clause	  	 	9	 
	 Section 1.04
	  	Benefits of Instrument	  	 	9	 
	 Section 1.05
	  	Relation to Base Indenture	  	 	10	 
	 Section 1.06
	  	Construction and Interpretation	  	 	10	 
			
	 	  	ARTICLE II	  	 	 
	
	 FORM AND TERMS OF THE SECURITIES; INTEREST AND
PAYMENTS
	  

			
	 Section 2.01
	  	Establishment of Securities; Form and Certain Terms of Securities	  	 	11	 
	 Section 2.02
	  	Interest	  	 	12	 
	 Section 2.03
	  	Interest Payments Discretionary	  	 	12	 
	 Section 2.04
	  	Restriction on Interest Payments	  	 	12	 
	 Section 2.05
	  	Effect of Interest Cancellation	  	 	14	 
	 Section 2.06
	  	Notice of Interest Cancellation	  	 	14	 
	 Section 2.07
	  	Determination of Interest Calculation Agent	  	 	14	 
			
	 	  	ARTICLE III	  	 	 
			
	 	  	REDEMPTION AND PURCHASE	  	 	 
			
	 Section 3.01
	  	Redemption	  	 	14	 
	 Section 3.02
	  	Notice of Redemption; Automatic Revocation	  	 	15	 
	 Section 3.03
	  	Conditions to Redemption and Purchase	  	 	15	 
	 Section 3.04
	  	Optional Purchases	  	 	16	 
			
	 	  	ARTICLE IV	  	 	 
			
	 	  	CONVERSION OF THE SECURITIES	  	 	 
			
	 Section 4.01
	  	Conversion upon Trigger Event	  	 	16	 
	 Section 4.02
	  	Conversion Shares	  	 	18	 
	 Section 4.03
	  	Settlement Procedure	  	 	19	 
	 Section 4.04
	  	Failure to Deliver a Conversion Shares Settlement Notice	  	 	19	 
	 Section 4.05
	  	Adjustment of Floor Price	  	 	20	 
	 Section 4.06
	  	Covenants Relating to Conversion Shares	  	 	20	 

  
 - ii - 

							
		  	ARTICLE V	  			
			
		  	DUTCH BAIL-IN POWER	  			
			
	 Section 5.01
	  	Agreement and Acknowledgment with Respect to Exercise of Dutch Bail-in Power	  	 	21	 
			
		  	ARTICLE VI	  			
			
		  	DEFAULTS AND REMEDIES	  			
			
	 Section 6.01
	  	Liquidation Event	  	 	24	 
	 Section 6.02
	  	Failure to Pay Principal Amount	  	 	24	 
	 Section 6.03
	  	Performance Obligations	  	 	24	 
	 Section 6.04
	  	No Other Remedies and Other Terms	  	 	24	 
	 Section 6.05
	  	Waiver of Past Defaults	  	 	25	 
			
		  	ARTICLE VII	  			
			
		  	SUBORDINATION AND SET-OFF	  			
			
	 Section 7.01
	  	Subordination	  	 	25	 
	 Section 7.02
	  	No Set-Off	  	 	26	 
			
		  	ARTICLE VIII	  			
			
		  	ADDITIONAL TRUSTEE PROTECTIONS	  			
			
	 Section 8.01
	  	Conversion	  	 	26	 
	 Section 8.02
	  	Indemnification by the Company	  	 	27	 
			
		  	ARTICLE IX	  			
	
	 ADDITIONAL ACKNOWLEDGEMENTS AND AGREEMENTS OF HOLDERS
AND BENEFICIAL OWNERS
	  

			
	 Section 9.01
	  	Dutch Bail-in Power	  	 	27	 
	 Section 9.02
	  	Conversion Upon a Trigger Event	  	 	28	 
	 Section 9.03
	  	Interest Cancellation	  	 	28	 
	 Section 9.04
	  	Waiver of Claims	  	 	28	 
	 Section 9.05
	  	Successors and Assigns	  	 	28	 
			
		  	ARTICLE X	  			
			
		  	 ADDITIONAL AMOUNTS
	  			
			
	 Section 10.01
	  	Additional Amounts	  	 	28	 

  
 - iii - 

									
		 		  	ARTICLE XI	  			
				
		 		  	AMENDMENTS TO THE INDENTURE	  			
				
	Section 11.01	 		  	Supplemental Indentures Without Consent of Holders	  	 	30	 
				
		 		  	ARTICLE XII	  			
				
		 		  	 MISCELLANEOUS PROVISIONS
	  			
				
	Section 12.01	 		  	Effectiveness	  	 	31	 
	Section 12.02	 		  	Modification	  	 	31	 
	Section 12.03	 		  	Original Issue	  	 	31	 
	Section 12.04	 		  	Ratification and Integral Part	  	 	31	 
	Section 12.05	 		  	Priority	  	 	32	 
	Section 12.06	 		  	Successors and Assigns	  	 	32	 
	Section 12.07	 		  	Counterparts	  	 	32	 
	Section 12.08	 		  	Governing Law	  	 	33	 
				
	ANNEX I	 	 –  
	  	Anti-Dilution Provisions	  	 	I-1	 
	EXHIBIT A-1	 	 –  
	  	Form of Security 	  	 	A-1-1	 
	EXHIBIT A-2	 	 –  
	  	Form of Security 	  	 	A-2-1	 
	EXHIBIT B	 	 –  
	  	Form of Conversion Notice	  	 	B-1	 
	EXHIBIT C	 	 –  
	  	Form of Conversion Shares Settlement Notice	  	 	C-1	 

  
 - iv - 

 FOURTH SUPPLEMENTAL INDENTURE, dated as of
September 14, 2021 (this “Fourth Supplemental Indenture”) between ING GROEP N.V., a holding company duly organized and existing under the laws of The Netherlands (herein called the “Company”), having
its corporate seat in Amsterdam, The Netherlands, and its principal office at Bijlmerdreef 106, 1102 CT Amsterdam, The Netherlands, and THE BANK OF NEW YORK
MELLON, LONDON BRANCH, a New York banking corporation, as Trustee (herein called the “Trustee”), having its Corporate Trust Office at One Canada Square, London E14 5AL, United Kingdom, to
the CAPITAL SECURITIES INDENTURE, dated as of April 16, 2015, between the Company and the Trustee, as amended from time to time (the “Base Indenture” and, together with this Fourth
Supplemental Indenture, the “Indenture”). 
 RECITALS OF THE
COMPANY 
 The Company and the Trustee are parties to the Base Indenture, which provides for the issuance by the Company from
time to time of Capital Securities in one or more series. 
 Section 9.01(f) of the Base Indenture permits supplements thereto without
the consent of Holders of Capital Securities to establish the form or terms of Capital Securities of any series as permitted by Sections 2.01 and 3.01 of the Base Indenture. 

As contemplated by Section 3.01 of the Base Indenture, the Company intends to issue two new series of Capital Securities to be known as
the Company’s “$1,000,000,000 3.875% Perpetual Additional Tier 1 Contingent Convertible Capital Securities” (the “2027 Securities”) and “$1,000,000,000 4.250% Perpetual Additional Tier 1 Contingent Convertible
Capital Securities” (the “2031 Securities” and, together with the 2027 Securities, the “Securities”) under the Indenture. 

The Company intends to amend certain other provisions in the Base Indenture, as set forth in Article IV of this Fourth Supplemental Indenture,
to apply to all series of Capital Securities created under the Indenture, the Securities and all future Capital Securities created under the Indenture; 

The Company has taken all necessary corporate action to authorize the execution and delivery of this Fourth Supplemental Indenture. 

NOW, THEREFORE, THIS FOURTH SUPPLEMENTAL INDENTURE
WITNESSETH: 
 For and in consideration of the premises and the purchase of the Securities by the Holders thereof, it is
mutually covenanted and agreed, for the equal and proportionate benefit of all Holders of the Securities as follows: 
 ARTICLE I 

DEFINITIONS AND OTHER PROVISIONS OF GENERAL
APPLICATION 
 Section 1.01 Definitions. Except as otherwise expressly provided or unless the context otherwise
requires, all terms used in this Fourth Supplemental Indenture that are defined in the Base Indenture shall have the meanings ascribed to them in the Base Indenture. Certain terms used principally in Annex I (Anti-Dilution Provisions)
are defined therein. The following terms used in this Fourth Supplemental Indenture have the following respective meanings with respect to the Securities only: 

“2027 Securities First Reset Date” means November 16, 2027. 

 “2031 Securities First Reset Date” means November 16,
2031. 
 “2027 Securities Reset Dates” means the 2027 Securities First Reset Date and each five-year
anniversary thereafter. 
 “2031 Securities Reset Dates” means the 2031 Securities First Reset Date and each
five-year anniversary thereafter. 
 “Additional Tier 1 Capital” at any time, has the meaning given thereto
(or to any equivalent term) at such time, by the Capital Regulations. 
 “ADS” means an American Depositary
Share representing one Ordinary Share. 
 “ADS Depositary” means JPMorgan Chase Bank, as the depositary
under the Company’s ADS Depositary Facility, or any successor thereto. 
 “ADS Depositary Facility”
means the facility under which the American Depositary Receipts (“ADRs”) representing ADSs may be issued pursuant to the Amended and Restated Deposit Agreement, dated as of October 4, 2018, among the Company, the ADS Depositary
and the holders from time to time of the ADRs, or any successor or replacement facility. 
 “Alternative Delivery
Arrangements” has the meaning set forth in Section 4.01(a). 
 “Amending Act” means the Act
implementing Article 48(7) of Directive (EU) 2019/879 of the European Parliament and of the Council of May 20, 2019. 

“Bank” means ING Bank N.V. 

“Base Indenture” has the meaning set forth in the first paragraph of this Fourth Supplemental Indenture. 

“Beneficial Owner” means (i) with respect to any Global Security, a beneficial owner of an interest
therein prior to the occurrence of the Final Cancellation Date and (ii) with respect to any definitive Security, the Holder in whose name the Security is registered in the Security Register. 

“BRRD” means Directive 2014/59/EU of the European Parliament and of the Council dated May 15, 2014, as
amended or replaced from time to time (including by the Directive (EU) 2019/879 of the European Parliament and of the Council of May 20, 2019). 

“Business Day” means any day other than a Saturday or Sunday or a day on which banking institutions are
authorized or obligated by law or executive order to close in London, Amsterdam or The City of New York. 

“Cancellation Date” means (i) with respect to any Security for which a Conversion Shares Settlement
Notice is received by the Conversion Shares Depository on or before the Notice Cut-Off Date, the applicable Settlement Date and (ii) with respect to any Security for which a Conversion Shares Settlement Notice is not received by the Conversion
Shares Depository on or before the Notice Cut-Off Date, the Final Cancellation Date. 

  
 -2- 

 “Capital Regulations” means, at any time, any requirements
of Dutch law or contained in the regulations, requirements, guidelines and policies of the Competent Authority or the resolution authority, or of the European Parliament and the European Council and of the European Banking Authority, then in effect
or applied in The Netherlands relating to capital adequacy and applicable to the Company, the Bank or the Group, including but not limited to the CRD IV Directive and the CRR (including Articles 77 and 78 thereof, as amended), Commission Delegated
Regulation (EU) No 241/2014 and the SRMR and taking into account any transitional arrangements thereunder. 

“Company” has the meaning set forth in the first paragraph of this Fourth Supplemental Indenture, and includes
any successor entity. 
 “Comparable Treasury Issue” means, with respect to any Reset Period, the U.S.
Treasury security or securities selected by the Company with a maturity date on or about the last day of such Reset Period and that would be utilized, at the time of selection and in accordance with customary financial practice, in pricing new
issues of corporate debt securities denominated in U.S. dollars and having a maturity of five years. 
 “Comparable
Treasury Price” means, with respect to any Reset Date, (i) the arithmetic average of the Reference Treasury Dealer Quotations for such Reset Date (calculated on the Reset Determination Date for such Reset Date), after excluding the
highest and lowest such Reference Treasury Dealer Quotations, or (ii) if fewer than five such Reference Treasury Dealer Quotations are received, the arithmetic average of all such quotations, or (iii) if fewer than two such Reference
Treasury Dealer Quotations are received, then such Reference Treasury Dealer Quotation as quoted in writing to the Interest Calculation Agent by a Reference Treasury Dealer. 

“Competent Authority” means the European Central Bank or any other body or authority having primary
supervisory authority with respect to the Company, the Bank or the Group. 
 “Conversion” means the
irrevocable and automatic release of all of the Company’s obligations to the Holders and Beneficial Owners of the Securities under the Securities in consideration of the Company’s issuance of the Conversion Shares at the Conversion Price
to the Conversion Shares Depository (on behalf of the Holders and Beneficial Owners of the Securities) or to the relevant recipient of such Conversion Shares pursuant to any Alternative Delivery Arrangements. 

“Conversion Calculation Agent” has the meaning set forth in Section 4.05(b). 

“Conversion Date” means the date specified in the Conversion Notice on which the Conversion takes place. 

“Conversion Notice” means a written notice substantially in the form attached hereto as Exhibit B. 

“Conversion Price” means (i) if the Ordinary Shares are then admitted to trading on a Relevant Stock
Exchange, the highest of (a) the Current Market Price per Ordinary Share translated into U.S. dollars at the Prevailing Rate, (b) the Floor Price and (c) the nominal value of an Ordinary Share translated into U.S. dollars at the
Prevailing Rate, and (ii) if the Ordinary Shares are not then admitted to trading on a Relevant Stock Exchange, the higher of (x) the Floor Price and (y) the nominal value of an Ordinary Share translated into U.S. dollars at the
Prevailing Rate. The Current Market Price, Floor Price and Prevailing Rate shall each be determined on the date on which the Conversion Notice is given. 

  
 -3- 

 “Conversion Shares” means Ordinary Shares to be issued to
the Conversion Shares Depository (or to the relevant recipient in accordance with the terms of the Securities) following a Conversion; 

“Conversion Shares Depository” has the meaning set forth in Section 4.01(a). 

“Conversion Shares Settlement Notice” means a written notice substantially in the form attached hereto as
Exhibit C. 
 “CRD IV” means the legislative package consisting of the CRD IV Directive and the CRR.

 “CRD IV Directive” means the Directive (2013/36 EU) of the European Parliament and of the Council on the
access to the activity of credit institutions and the prudential supervision of credit institutions and investment firms dated June 26, 2013, as amended or replaced from time to time (including by Directive (EU) 2019/878 of the European
Parliament and of the Council of May 20, 2019). 
 “CRR” means Regulation (EU) No. 575/2013 of the
European Parliament and of the Council on prudential requirements for credit institutions and investment firms dated June 26, 2013, as amended or replaced from time to time (including by Regulation (EU) 2019/876 of the European Parliament and
of the Council dated May 20, 2019). 
 “Current Market Price” has the meaning set forth in Annex
I (Anti-Dilution Provisions). 
 “Default” means (i) an Event of Default, (ii) a
Payment Default or (iii) the breach by the Company of a Performance Obligation. 
 “Distributable
Items” shall have the meaning assigned to such term in the CRR, as interpreted and applied in accordance with the Capital Regulations then applicable to the Company. 

“Dutch Bail-in Power” means any statutory write-down and/or conversion
power existing from time to time under any laws, regulations, rules or requirements relating to the resolution of banks, banking group companies, credit institutions and/or investment firms incorporated in The Netherlands in effect and applicable in
The Netherlands to the Company or other members of the Group, including but not limited to any such laws, regulations, rules or requirements (including, but not limited to, the Dutch Financial Supervision Act (Wet op het financieel toezicht))
that are implemented, adopted or enacted within the context of a European Union directive or regulation of the European Parliament and of the Council establishing a framework for the recovery and resolution of credit institutions and investment
firms (including but not limited to the BRRD and the SRMR, in each case as amended or superseded) and/or within the context of a Dutch resolution regime under the Dutch Intervention Act (as implemented in relevant statutes) and any amendments
thereto or otherwise, pursuant to which obligations of a bank, banking group company, credit institution or investment firm or any of its affiliates can be reduced, cancelled and/or converted into shares or other securities or obligations of the
obligor or any other person (whether at the point of non-viability or as taken together with a resolution action) or may be expropriated. 

  
 -4- 

 “Effective Date” means the date on which the Amending Act
becomes effective in The Netherlands. 
 “Euronext Amsterdam” means Euronext in Amsterdam, a regulated
market of Euronext Amsterdam N.V. 
 “Existing Capital Instruments” means the ING Perpetual Securities II
issued on June 19, 2003, ING Perpetual Securities III issued on June 16, 2004, 6.125% ING Perpetual Debt Securities issued on September 26, 2005, 6.000% Perpetual Additional Tier 1 Contingent Convertible Capital Securities issued on
April 16, 2015, 6.500% Perpetual Additional Tier 1 Contingent Convertible Capital Securities issued on April 16, 2015, 6.875% Perpetual Additional Tier 1 Contingent Convertible Capital Securities issued on November 21, 2016, 6.750%
Perpetual Additional Tier 1 Contingent Convertible Capital Securities issued on February 26, 2019 and 4.875% Perpetual Additional Tier 1 Contingent Convertible Capital Securities issued on February 26, 2020. 

“Final Cancellation Date” means the date, as specified in the Conversion Notice, on which the Securities in
relation to which no Conversion Shares Settlement Notice has been received by the Conversion Shares Depository on or before the Notice Cut-Off Date shall be cancelled, which date may be up to fifteen
(15) Business Days following the Notice Cut-Off Date. 
 “First Reset
Date” means, with respect to the 2027 Securities, the 2027 Securities First Reset Date and, with respect to the 2031 Securities, the 2031 Securities First Reset Date. 

“Floor Price” means $9.00 per Conversion Share (subject to certain anti-dilution adjustments pursuant to
Section 4.05). 
 “Further Capital Securities” means any securities issued after the Issue Date which
are contingently convertible into Ordinary Shares pursuant to their terms in the event that the Group CET1 Ratio is less than a specified percentage. 

“Group” means the Company and its consolidated subsidiaries. 

“Group CET1 Capital” means, at any time and expressed in euro, the Common Equity Tier 1 capital (or an
equivalent or successor term) at such time, of the Company calculated in accordance with Article 11(2) of the CRR on the basis of the consolidated situation of the Company as the parent financial holding company of the Bank and taking into account
any transitional arrangements under the Capital Regulations. 
 “Group CET1 Ratio” means, as of any date,
the ratio of the aggregate amount of Group CET1 Capital to the Group Total Risk Exposure Amount as of the same date, expressed as a percentage. 

“Group Total Risk Exposure Amount” means, at any time and expressed in euro, the total risk exposure amount
(or an equivalent or successor term) at such time, of the Company calculated in accordance with Article 11(2) of the CRR on the basis of the consolidated situation of the Company as the parent financial holding company for the Bank, in accordance
with the Capital Regulations and taking into account any transitional arrangements under the Capital Regulations. 

  
 -5- 

 “Indenture” has the meaning set forth in the first
paragraph of this Fourth Supplemental Indenture. 
 “Independent Conversion Adviser” means an independent
financial institution of international repute or independent financial adviser with appropriate expertise (which may include the initial Conversion Calculation Agent) appointed by the Company at its own expense. 

“Interest Calculation Agent” means The Bank of New York Mellon, London Branch, or its successor appointed by
the Company pursuant to the Interest Calculation Agent Agreement between the Company and The Bank of New York Mellon, London Branch, dated as of the date hereof. 

“Interest Payment Date” has the meaning set forth in Section 2.02(a). 

“Interest Period” means the period from and including an Interest Payment Date (or the Issue Date, in the case
of the initial Interest Period) to but excluding the next succeeding Interest Payment Date. 
 “Issue Date”
has the meaning set forth in Section 2.01(b). 
 “Liquidation Event” means a liquidation (upon
dissolution (ontbinding) or otherwise), moratorium of payments (surseance van betaling) or bankruptcy (faillissement) of the Company; provided that the exercise of the Dutch Bail-in
Power by the Relevant Resolution Authority with respect to the Securities shall not constitute a Liquidation Event. 

“Maximum Distributable Amount” means any applicable maximum distributable amount relating to the Company
required to be calculated in accordance with Article 141 of the CRD IV Directive as amended or replaced from time to time or, as the case may be, any provision of applicable law, including the Dutch Financial Supervision Act (Wet op het
financieel toezicht), transposing or implementing the CRD IV Directive, as amended, supplemented or replaced and as in force and applicable in The Netherlands from time to time or, as applicable, any analogous restrictions arising from the
requirement to meet capital buffers under Capital Regulations or the BRRD (including without limitation Article 16a thereof). 

“MiFID II” means Directive (EU) 2014/65 (as amended). 

“Notice Cut-Off Date” means the date specified as such in the
Conversion Notice, which date shall be at least twenty (20) Business Days following the Suspension Date. 

“Ordinary Shares” means fully paid Ordinary Shares in the capital of the Company. 

“Parity Instruments” means securities, instruments or obligations of the Company which upon a Liquidation
Event occurring prior to the Trigger Event rank, or are expressed to rank, pari passu with the Securities, including the Existing Capital Instruments. 

“Payment Default” means the failure to pay the principal amount of the Securities within 14 days of the date
fixed for redemption of the Securities, provided that the notice of such redemption shall not have been revoked pursuant to Section 3.02 and the conditions to redemption set forth in Section 3.03 shall have been satisfied on the date fixed
for redemption. 

  
 -6- 

 “Performance Obligation” means any term, obligation or
condition binding upon the Company under the Securities or under the Indenture with respect to the Securities other than any obligation to pay principal of, or interest on, any Securities or any obligation to pay Additional Amounts in respect
thereof (whether upon redemption, the occurrence of a Liquidation Event or otherwise). 
 “Prevailing Rate”
means, in respect of any pair of currencies on any calendar day, the spot rate of exchange between the relevant currencies prevailing at or about 12:00 pm, London time, on that date as appearing on or derived from the Relevant Page or, if such a
rate cannot be determined at such time, the rate prevailing at or about 12:00 pm, London time, on the immediately preceding day on which such rate can be so determined or, if such rate cannot be so determined by reference to the Relevant Page, the
rate determined in such other manner as an Independent Conversion Adviser shall in good faith prescribe. 

“Reference Treasury Dealer” means each of up to five banks selected by the Company (following, where
practicable, consultation with the Interest Calculation Agent), or the affiliates of such banks, which are (i) primary U.S. Treasury securities dealers, and their respective successors, or (ii) market makers in pricing corporate bond
issues denominated in U.S. dollars. 
 “Reference Treasury Dealer Quotations” means with respect to each
Reference Treasury Dealer and any Reset Date, the arithmetic average, as determined by the Interest Calculation Agent, of the bid and offered prices for the applicable Comparable Treasury Issue, expressed in each case as a percentage of its
principal amount, at 11:00 a.m. (New York City time), on the Reset Determination Date for such Reset Date. 

“Regular Record Date” means the Business Day immediately preceding each Interest Payment Date (or, if the
Securities are issued in the form of definitive Securities, the fifteenth (15th) Business Day preceding each Interest Payment Date). 

“Regulatory Event” means that, as a result of a change in the regulatory classification of the Securities on
or after the Issue Date, the Securities have been or will be excluded from the own funds of the Company, calculated in accordance with Article 11 of the CRR on the basis of the consolidated situation of the Company as the parent financial holding
company for the Bank, or reclassified as a lower quality form of own funds (that is, no longer Additional Tier 1 Capital), in each case whether in whole or in part. 

“Relevant Page” means the relevant page on Bloomberg or such other information service provider that displays
the relevant information, as determined by the Conversion Calculation Agent. 
 “Relevant Resolution
Authority” means any authority with the ability to exercise a Dutch Bail-in Power. 

“Relevant Stock Exchange” means Euronext Amsterdam or, if at the relevant time the Ordinary Shares are not at
that time listed and admitted to trading on the Euronext Amsterdam, the principal stock exchange or securities market (if any) on which the Ordinary Shares are then listed, admitted to trading or quoted or accepted for dealing. 

“Reset Date” means, with respect to the 2027 Securities, each of the 2027 Securities Reset Dates and, with
respect to the 2031 Securities, each of the 2031 Securities Reset Dates. 

  
 -7- 

 “Reset Determination Date” means, with respect to each
applicable Reset Date, the second (2nd) Business Day immediately preceding such Reset Date. 

“Reset Period” means any period from and including each applicable Reset Date to but excluding the next
succeeding applicable Reset Date. 
 “Securities” has the meaning set forth in the Recitals. 

“Senior Instruments” means securities, instruments or obligations of the Company: (i) the holders of
which are unsubordinated creditors of the Company (“Unsubordinated Instruments”), or (ii) which are, or are expressed to be, subordinated (whether only in the event of the liquidation of the Company or otherwise) to
Unsubordinated Instruments but not further or otherwise, or (iii) which in a liquidation, moratorium or bankruptcy of the Company occurring prior to the Trigger Event are, or are expressed to be, further or otherwise subordinated, other than
those which in such event rank, or are expressed to rank, pari passu with or junior to the Securities. For the avoidance of doubt, “Senior Instruments” includes securities, instruments or obligations of the Company which are
Tier 2 instruments within the meaning of Article 52(1)(d) of the CRR. 
 “Settlement Date” means
(i) with respect to any Security in relation to which a Conversion Shares Settlement Notice is received by the Conversion Shares Depository (or the relevant recipient, as applicable) on or before the Notice
Cut-Off Date, the date which is two (2) Business Days after (a) the date on which such Conversion Shares Settlement Notice has been received by the Conversion Shares Depository or (b) (if later) the
date on which the Conversion Shares are delivered to the Conversion Shares Depository, and (ii) with respect to any Security in relation to which a Conversion Shares Settlement Notice is not received by the Conversion Shares Depository on or
before the Notice Cut-Off Date, the date on which the Conversion Shares Depository delivers the relevant Conversion Shares. 

“Shareholders” means the holders of Ordinary Shares. 

“SRMR” means the provisions of Regulation (EU) No 806/2014 of the European Parliament and of the Council. 

“Suspension Date” means the date specified in the Conversion Notice as the date on which DTC is expected to
suspend all clearance and settlement of transactions in the Securities in accordance with its rules and procedures. 

“Tax Event” shall mean the Company determining that, as a result of a Tax Law Change, the Company
(a) will or would be required on the next Interest Payment Date (or if the next Interest Payment Date is scheduled to occur within thirty (30) days, then on the Interest Payment Date immediately following the next Interest Payment Date) to
pay Holders Additional Amounts; or (b) would not be entitled to claim a deduction in respect of any interest payments made on the next Interest Payment Date (or if the next Interest Payment Date is scheduled to occur within thirty
(30) days, then on the Interest Payment Date immediately following the next Interest Payment Date) in computing the Company’s taxation liabilities in The Netherlands, or the amount of the deduction would be materially reduced, save to the
extent that such Tax Law Change merely codifies, rules or otherwise confirms that the interest payment would not be or was not deductible based on applicable law as at the Issue Date; provided in each of the case of (a) and (b)
that the consequences of such event cannot be avoided by the Company taking reasonable measures available to it. 

  
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 “Tax Law Change” means a change in or amendment to, the
laws or regulations of The Netherlands or any political subdivision or authority therein or thereof having the power to tax, including any treaty to which The Netherlands is a party, or any change in the application of official or generally
published interpretation of such laws or regulations, including a decision of any court or tribunal, or any interpretation or pronouncement by any relevant tax authority, which change or amendment (including, for the avoidance of doubt, a decision
of any court or tribunal) becomes, or would become, effective on or after the Issue Date. 
 “Tradable
Amount” has the meaning set forth in Section 2.01(j). 
 “Trigger Event” shall occur at any
time the Company, the Competent Authority or any agent appointed for such purpose by the Competent Authority has determined that the Group CET1 Ratio is less than 7.00%. 

“Trigger Event Officers’ Certificate” has the meaning set forth in Section 4.01(a)(ii). 

“Trustee” has the meaning set forth in the first paragraph of this Fourth Supplemental Indenture. 

“U.S. Treasury Rate” means, with respect to any Reset Date from which such rate applies, the rate per annum
equal to: (1) the yield, under the heading which represents the average for the week immediately prior to the Reset Determination Date for such Reset Date, appearing in the most recently published statistical release designated
“H.15”, or any successor publication that is published by the Board of Governors of the Federal Reserve System that establishes yields on actively traded U.S. Treasury securities adjusted to constant maturity, under the caption
“Treasury Constant Maturities”, for the maturity of five years; or (2) if such release (or any successor release) is not published during the week immediately prior to the Reset Determination Date or does not contain such yields, the
rate per annum equal to the semiannual equivalent yield to maturity of the Comparable Treasury Issue, calculated using a price for the Comparable Treasury Issue (expressed as a percentage of its principal amount) equal to the Comparable Treasury
Price for such Reset Date. The U.S. Treasury Rate shall be calculated by the Interest Calculation Agent. If the U.S. Treasury Rate cannot be determined, for whatever reason, as described under (1) or (2) above, the “U.S. Treasury
Rate” means the rate in percentage per annum as notified by the Interest Calculation Agent to the Company equal to the yield on U.S. Treasury securities having a maturity of five years as set forth in the most recently published statistical
release designated “H.15” under the caption “Treasury Constant Maturities” (or any successor publication that is published weekly by the Board of Governors of the Federal Reserve System and that establishes yields on actively
traded U.S. Treasury securities adjusted to constant maturity under the caption “Treasury Constant Maturities” for the maturity of five years) at 5:00 p.m. (New York City time) on the last available date preceding the Reset Determination
Date on which such rate was set forth in such release (or any successor release). 
 Section 1.02 Effect of Headings. The
Article and Section headings herein are for convenience only and shall not affect the construction hereof. 
 Section 1.03
Separability Clause. In case any provision in this Fourth Supplemental Indenture shall be invalid, illegal or unenforceable, the validity, legality and enforceability of the remaining provisions shall not in any way be affected or
impaired thereby. 
 Section 1.04 Benefits of Instrument. Nothing in this Fourth Supplemental Indenture, express or implied, shall
give to any person, other than the parties hereto and their successors hereunder and the Holders of the Securities, any benefit or any legal or equitable right, remedy or claim under the Indenture. 

  
 -9- 

 Section 1.05 Relation to Base Indenture. 

(a) This Fourth Supplemental Indenture constitutes an integral part of the Base Indenture. Notwithstanding any other provision of this
Fourth Supplemental Indenture, all provisions of this Fourth Supplemental Indenture are expressly and solely for the benefit of the Holders and Beneficial Owners of the Securities and, subject to Section 1.05(c), any such provisions shall not
be deemed to apply to any other Capital Securities issued under the Base Indenture and shall not be deemed to amend, modify or supplement the Base Indenture for any purpose other than with respect to the Securities. 

(b) Section 10.04(a) of the Base Indenture shall not apply with respect to the Securities and is to be replaced and superseded by Article X
hereof. Any references herein to Section 10.04 of the Base Indenture shall be deemed to include Article X hereof in lieu of Section 10.04(a) of the Base Indenture as if stated therein. 

(c) The first and fifth paragraphs of Section 3.03 in the Base Indenture are to be replaced and superseded by Sections 11.01(a) and
11.01(b) of Article XI hereof, respectively, with respect to all series of Capital Securities created under the Base Indenture, the Securities and all future Capital Securities created under the Base Indenture. 

(d) With respect to the Securities, this Fourth Supplemental Indenture shall control in the event of any conflict or inconsistency between
this Fourth Supplemental Indenture and the Base Indenture. 
 Section 1.06 Construction and Interpretation. Unless the
express otherwise requires: 
 (a) the words “hereof”, “herein” and “hereunder” and words of similar import,
when used in this Fourth Supplemental Indenture, refer to this Fourth Supplemental Indenture as a whole and not to any particular provision of this Fourth Supplemental Indenture; 

(b) the terms defined in the singular have a comparable meaning when used in the plural, and vice versa; 

(c) references herein to a specific Section, Article or Exhibit refer to Sections or Articles of, or an Exhibit to, this Fourth Supplemental
Indenture; 
 (d) wherever the words “include”, “includes” or “including” are used in this Fourth Supplemental
Indenture, they shall be deemed to be followed by the words “without limitation;” 
 (e) references to a Person are also to its
successors and permitted assigns; 
 (f) the use of “or” is not intended to be exclusive unless expressly indicated otherwise;

 (g) references to any act or statute or any provision of any act or statute shall be deemed also to refer to any statutory modification
or re-enactment thereof or any statutory instrument, order or regulation made thereunder or under such modification or re-enactment; and 

  
 -10- 

 (h) references to any issue or offer or grant to Shareholders “as a class” or
“by way of rights” shall be taken to be references to an issue or offer or grant to all or substantially all Shareholders, as the case may be, other than Shareholders, as the case may be, to whom, by reason of the laws of any territory or
requirements of any recognized regulatory body or any other stock exchange or securities market in any territory or in connection with fractional entitlements, it is determined not to make such issue or offer or grant. 

ARTICLE II 
 FORM
AND TERMS OF THE SECURITIES; INTEREST AND PAYMENTS 

Section 2.01 Establishment of Securities; Form and Certain Terms of Securities. 

(a) There is hereby established two new series of Capital Securities under the Base Indenture entitled the “$1,000,000,000 3.875%
Perpetual Additional Tier 1 Contingent Convertible Capital Securities” and the “$1,000,000,000 4.250% Perpetual Additional Tier 1 Contingent Convertible Capital Securities.” The 2027 Securities and the 2031 Securities shall be
executed and delivered in substantially the form attached hereto as Exhibit A-1 and Exhibit A-2, respectively. The Securities shall be
initially issued in the form of one or more Global Securities. The Company hereby designates DTC as the Depositary for the Securities. 

(b) The Company shall issue the 2027 Securities in an aggregate principal amount of $1,000,000,000 and the 2031 Securities in an aggregate
principal amount of $1,000,000,000, in each case on September 14, 2021 (the “Issue Date”). The Company may issue additional Securities of each series from time to time after the Issue Date in the manner and to the extent permitted
by Section 3.01 of the Base Indenture. 
 (c) The Securities shall be perpetual and redeemable by the Company as provided in Article
III. The Securities shall not have a sinking fund and are not redeemable at the option of the Holders of the Securities. 
 (d) Interest
shall be payable on the Securities as provided in Sections 2.02 through 2.06 and Additional Amounts shall be payable in respect of the Securities in accordance with Section 10.04 of the Base Indenture. 

(e) The Company hereby appoints the Trustee, acting through its office at One Canada Square, London E14 5AL, to act as Paying Agent for the
Securities. 
 (f) The Securities shall be automatically convertible as provided in Article IV. The Securities are not convertible at the
option of the Holders of the Securities. 
 (g) The Securities shall be subject to the Dutch Bail-in
Power as provided in Article V. 
 (h) The Securities constitute the direct unsecured obligations of the Company ranking pari passu
without any preference among themselves and shall rank subordinate to Senior Instruments as provided in Article VII. 
 (i) The events of
default and remedies with respect to the Securities shall be limited as provided in Article VI. 

  
 -11- 

 (j) The Securities shall be issued in denominations of $200,000 in principal amount and
integral multiples of $1,000 in excess thereof. The denomination of each Security (or any interest therein) shall be its “Tradable Amount.” Prior to a Conversion, the Tradable Amount of any Security (or any interest therein) shall
equal its principal amount. Following a Conversion, the principal amount of each Security shall equal zero, but its Tradable Amount shall remain unchanged as a result of the Conversion. 

Section 2.02 Interest. 

(a) The interest rate on the 2027 Securities shall be (i) from and including the Issue Date to but excluding the 2027 Securities
First Reset Date 3.875% per annum and (ii) from and including each 2027 Securities Reset Date to but excluding the following 2027 Securities Reset Date, the sum of the applicable U.S. Treasury Rate on the relevant Reset Determination
Date and 2.862%. The interest rate on the 2031 Securities shall be (i) from and including the Issue Date to but excluding the 2031 Securities First Reset Date 4.250% per annum and (ii) from and including each 2031 Securities Reset
Date to but excluding the following 2031 Securities Reset Date, the sum of the applicable U.S. Treasury Rate on the relevant Reset Determination Date and 2.862%. Subject to Sections 2.03 and 2.04, interest on the principal amount of each Security
shall be payable semiannually in arrears on May 16 and November 16 of each year (each, an “Interest Payment Date”), commencing on November 16, 2021, and shall be computed on the basis of a year of 360 days consisting
of twelve (12) months of thirty (30) days each and, in the case of an incomplete month, the actual number of days elapsed. The first date on which interest may be paid will be November 16, 2021 for the period commencing on (and
including) September 14, 2021, and ending on (but excluding) November 16, 2021. 
 Section 2.03 Interest Payments
Discretionary. Subject to Section 2.04, interest on the Securities shall be due and payable at the sole and absolute discretion of the Company. The Company shall have sole and absolute discretion at all times and for any reason to
cancel (in whole or in part) any interest payment that would otherwise be payable in respect of the Securities on any Interest Payment Date or Redemption Date. If the Company does not make an interest payment on any Interest Payment Date or
Redemption Date in whole or in part, such interest payment (or the portion thereof not paid) shall be deemed cancelled and shall not be due and payable whether or not the Company has provided notice of cancellation of such interest payment as set
forth in Section 2.06. An interest payment otherwise payable on an Interest Payment Date or Redemption Date that is not a Business Day will not be deemed cancelled if it is paid on the following Business Day. 

Section 2.04 Restriction on Interest Payments.  

(a) Without limiting the Company’s right to cancel any interest payment pursuant to Section 2.03 and subject to the extent permitted
in Section 2.04(b) in respect of partial interest payments in respect of the Securities, the Company shall not make an interest payment (including any Additional Amounts) in respect of the Securities on any Interest Payment Date or Redemption
Date (or the following Business Day, if such Interest Payment Date or Redemption Date, as the case may be, is not a Business Day) in whole or in part, if and to the extent that: 

 

	 	(i)	 the amount of such interest payment otherwise due, together with any interest payments or distributions which
have been paid or made or which are required to be paid or made during the then current financial year on other own funds items (which, for the avoidance of doubt, excludes any such interest payments or distributions which (i) are not required
to be made out of Distributable Items or (ii) have already been provided for, by way of deduction, in the calculation of Distributable Items), shall in the aggregate exceed the amount of Distributable Items of the Company as at such Interest
Payment Date or Redemption Date; 

  
 -12- 

	 	(ii)	 the payment of such interest, when aggregated together with certain other distributions of the kind referred to
in Article 141(2) of the CRD IV Directive (or any provision of applicable law, including the Dutch Financial Markets Supervision Act (Wet op het financieel toezicht), transposing or implementing Article 141(2) of the CRD IV Directive, as
amended or replaced, and as in force and applicable in The Netherlands from time to time), or, as applicable, any analogous restrictions arising from the requirement to meet capital buffers under Capital Regulations or the BRRD (including without
limitation Article 16a thereof), would cause the Maximum Distributable Amount, if any, then applicable to the Company to be exceeded; or 

  

	 	(iii)	 the payment of such interest is scheduled to be made on an Interest Payment Date falling on or after the date
of a Trigger Event or Liquidation Event. 

 (b) The Company may, however, in its sole discretion, elect to make a partial
interest payment in respect of the Securities to the extent that such partial interest payment may be made without breaching the restriction set forth in Section 2.04(a). 

  
 -13- 

 Section 2.05 Effect of Interest Cancellation. Interest on the Securities
shall only be due and payable on an Interest Payment Date to the extent it is not cancelled or deemed cancelled pursuant to Section 2.03 or 2.04. Any interest cancelled or deemed cancelled (in each case, in whole or in part) pursuant to
Sections 2.03 and 2.04 shall not be due and shall not accumulate or be payable at any time thereafter (including upon redemption of the Securities), and Holders and Beneficial Owners of the Securities shall have no rights thereto (whether upon
a Liquidation Event or otherwise) or to receive any additional interest or compensation as a result of such cancellation or deemed cancellation of interest in respect of the Securities. 

Section 2.06 Notice of Interest Cancellation. Notwithstanding anything to the contrary in the Indenture (including
Section 1.06 of the Base Indenture), if practicable, the Company shall provide notice of any cancellation of interest (in each case, in whole or in part) to the Trustee and the Holders of the Securities at least five (5) Business Days
prior to the relevant Interest Payment Date or Redemption Date and shall provide notice of any deemed cancellation of interest to the Trustee and the Holders of the Securities as promptly as practicable following the relevant Interest Payment Date
or Redemption Date. Failure to provide such notice shall have no impact on the effectiveness of, or otherwise invalidate, any such cancellation or deemed cancellation of interest, or give the Holders and Beneficial Owners of the Securities any
rights as a result of such failure. 
 Section 2.07 Determination of Interest Calculation Agent. All determinations and
calculations made by the Interest Calculation Agent shall be conclusive and binding on the Holders of the Securities, the Company and the Trustee, absent manifest error. 

ARTICLE III 

REDEMPTION AND PURCHASE 

Section 3.01 Redemption. 

(a) Subject to the limitations specified in Section 3.02, the Company may, at its option, redeem the Securities, in whole but not in
part: 
 (i) with respect to the 2027 Securities, on any calendar day during the
six-month period commencing on (and including) May 16, 2027 to (and including) the 2027 Securities First Reset Date (as defined herein) and on any Interest Payment Date (as defined herein) thereafter and,
with respect to the 2031 Securities, on any calendar day during the six-month period commencing on (and including) May 16, 2031 to (and including) the 2031 Securities First Reset Date and on any
subsequent Interest Payment Date; 
 (ii) at any time if a Regulatory Event has occurred and is then continuing; or 

(iii) at any time if a Tax Event has occurred and is then continuing; 

in each of cases (i) to (iii) above, at their principal amount, plus accrued and unpaid interest to the Redemption Date (including Additional Amounts, if
any), excluding any interest that has been cancelled or is deemed cancelled in accordance with Section 2.03 or Section 2.04. 

(b) Prior to giving notice of redemption pursuant to Section 3.01(a)(ii) or Section 3.01(a)(iii), the Company shall deliver to the
trustee a certificate signed by any two (2) members of the Executive Board stating that the conditions to such redemption have been satisfied. 

  
 -14- 

 (c) Prior to the delivery of any notice of redemption in respect of a redemption under
Section 3.01(a)(iii)the Company shall deliver to the Trustee an opinion from a recognized law or tax firm of international standing, chosen by the Company, in a form satisfactory to the Trustee, confirming that the Company is entitled to
exercise its right of redemption under Section 3.01(a)(iii). 
 Section 3.02 Notice of Redemption; Automatic
Revocation. 
 (a) Notice of redemption of the Securities shall be given as provided in Section 11.04 of the Base Indenture.
Such notice shall state the place or places where the Securities are to be surrendered for payment of the Redemption Price and that on the date specified for redemption, each Security shall be redeemed and the principal amount of each Security will
become due and payable and that, subject to certain exceptions, interest shall cease to accrue after the redemption date. A notice of redemption shall be irrevocable, except that the occurrence of a Trigger Event or Liquidation Event or the exercise
of the Dutch Bail-in Power by the Relevant Resolution Authority prior to the date fixed for redemption shall automatically revoke such notice and no Securities shall be redeemed and no payment in respect of
the Securities shall be due and payable. 
 (b) The Company shall not give a notice of redemption of the Securities following the occurrence
of a Trigger Event. 
 (c) The Company shall promptly deliver notice to the Trustee and the Holders of the Securities of any event that
shall have automatically revoked any redemption notice pursuant to Section 3.02(a). 
 Section 3.03 Conditions to Redemption
and Purchase. 
 (a) The Company may not give notice of any redemption of or redeem, nor may the Company or any member of the
Group purchase, any Securities unless the Company shall have obtained the prior permission of the Competent Authority. 
 (b) Any redemption
or purchase of the Securities is subject to the additional conditions as set out below, in each case if and to the extent required under the Capital Regulations: 
  

	 	(i)	 either (A) on or before such redemption or purchase of the Securities, the Company shall have replaced the
Securities with own funds instruments of equal or higher quality on terms that are sustainable for the Company’s income capacity or (B) the Company has demonstrated to the satisfaction of the Competent Authority that the available own
funds and eligible liabilities would, following such redemption or purchase, exceed the minimum capital requirements (including any capital buffer requirements) required under CRD IV by a margin that the Competent Authority considers necessary at
such time; and 

  

	 	(ii)	 in respect of a redemption prior to the fifth anniversary of the Issue Date, (A) in the case of redemption
due to the occurrence of a Regulatory Event, the Company shall have demonstrated to the satisfaction of the Competent Authority that the change in the regulatory classification of the Securities was not reasonably foreseeable as at the Issue Date;
or (B) in the case of redemption due to the occurrence of a Tax Event, the Company shall have demonstrated to the satisfaction of the Competent Authority that the change in the applicable tax treatment of the Securities is material and was not
reasonably foreseeable as at the Issue Date; and 

  
 -15- 

	 	(iii)	 if, at the time of such redemption or purchase, the Capital Regulations permit the redemption or purchase only
after compliance with one or more alternative or additional pre-conditions to those set out in (i) and (ii) above, the Company shall have complied with such other
pre-condition(s). 

 Section 3.04 Optional Purchases. The Company or
any member of the Group may purchase or procure others to purchase beneficially for its account any of the outstanding Securities in any manner and at any price, subject to the conditions set out in Section 3.03 and to applicable law and
regulation (which at the Issue Date shall include, without limitation, the Capital Regulations including Article 52(1)(i) of the CRR). 

ARTICLE IV 

CONVERSION OF THE SECURITIES 

Section 4.01 Conversion upon Trigger Event. 

(a) Upon the occurrence of a Trigger Event, the Company shall: 
  

	 	(i)	 immediately inform the Competent Authority of its occurrence; 

 

	 	(ii)	 deliver to the Trustee an Officers’ Certificate signed by two (2) members of the Executive Board
stating that a Trigger Event has occurred (a “Trigger Event Officers’ Certificate”); 

  

	 	(iii)	 appoint a reputable financial institution, trust company, depository entity, nominee entity or similar entity
that is wholly independent of the Company (the entity so appointed, the “Conversion Shares Depository”) as promptly as practicable thereafter; and 

 

	 	(iv)	 as promptly as practicable following the Company’s appointment of a Conversion Shares Depository (or of
its ascertaining that it is not reasonably able to do so) and the delivery of a Trigger Event Officers’ Certificate to the Trustee, and, in any event, within such period as the Competent Authority may require, the Company shall deliver a
Conversion Notice to the Trustee and to Holders of the Securities (via DTC). 

 As a condition of its appointment, the Conversion Shares
Depository shall be required to undertake, for the benefit of the Holders and Beneficial Owners of the Securities, to hold the Conversion Shares on their behalf in one or more segregated accounts and perform each function ascribed to it in this
Fourth Supplemental Indenture. If the Company is unable to appoint a Conversion Shares Depository prior to delivery of the Conversion Notice, it shall make such other arrangements as it deems reasonable to effect the delivery of the Conversion
Shares to or for the benefit of the Holders of the Securities (the “Alternative Delivery Arrangements”). Each Holder and Beneficial Owner of any Securities shall be deemed to have irrevocably directed the Company to issue the
Conversion Shares in accordance with such arrangements. 
 (b) A Conversion Notice shall be given substantially in the form of
Exhibit B, with such modifications as shall be reasonably necessary to reflect any Alternative Delivery Arrangements. Such Conversion Notice shall be completed consistent with the requirements of this Article IV and shall specify, among other
things: 
  

	 	(i)	 that a Trigger Event has occurred with respect to the Securities; 

  
 -16- 

	 	(ii)	 the Conversion Price; 

 

	 	(iii)	 a Conversion Date occurring without delay upon the occurrence of the Trigger Event and in any event within one
(1) month following the date of such Trigger Event and in accordance with the requirements set out in Article 54 of the CRR as at the Issue Date; 

  

	 	(iv)	 the Notice Cut-Off Date; and 

 

	 	(v)	 a Final Cancellation Date, which shall be to the extent practicable no more than fifteen (15) Business
Days following the Notice Cut-Off Date 

 A form of Conversion Shares Settlement Notice
substantially in the form of Exhibit C, with such modifications as shall be reasonably necessary to reflect any Alternative Delivery Arrangements or any changes in the procedures of the Depositary applicable to the Conversion, shall be
attached to the Conversion Notice as an annex thereto. 
 (c) If the outstanding Securities are issued in definitive form, the Trustee
shall mail the Conversion Notice to the Holders of the Securities at their addresses shown on the Security Register within two (2) Business Days of its receipt from the Company and, if the Securities are then held by DTC in the form of Global
Securities, the Trustee shall request that DTC post the Conversion Notice on its Reorganization Inquiry for Participants System pursuant to DTC’s procedures then in effect (or such other system as DTC uses for providing notices to holders of
securities). The date on which the Conversion Notice shall be deemed to have been given shall be the date on which it is delivered by the Company to DTC. 

(d) The Conversion shall occur on the Conversion Date specified in the Conversion Notice. On the Conversion Date, the Company shall issue
and deliver the Conversion Shares to the Conversion Shares Depository (or, if it shall not have been able to appoint a Conversion Shares Depository, pursuant to any Alternative Delivery Arrangements). All of the Company’s obligations to the
Holders and Beneficial Owners of the Securities under the Securities and the Indenture shall be irrevocably and automatically released in consideration of the Company’s issuance and delivery of such Conversion Shares on the Conversion Date
pursuant to this Section 4.01(d) and under no circumstances shall such released obligations be reinstated. Upon such issuance and delivery, (i) the principal amount of each Security shall automatically be reduced to zero and each Holder or
Beneficial Owner of a Security shall have recourse only to the Conversion Shares Depository for delivery of the Conversion Shares and (ii) the Securities shall remain in existence until the applicable Cancellation Date for the sole purpose of
evidencing the Holders and Beneficial Owners of the Securities’ right to receive Conversion Shares from the Conversion Shares Depository or pursuant to any Alternative Delivery Arrangements. Any interest in respect of an Interest Period ending
on any Interest Payment Date or Redemption Date falling between the date of a Trigger Event and the Conversion Date shall be deemed to have been cancelled upon the occurrence of such Trigger Event and shall not be due and payable. The Holders of the
Securities’ sole recourse for the Company’s failure to issue and deliver the Conversion Shares to the Conversion Shares Depository or pursuant to any Alternative Delivery Arrangements on the Conversion Date shall be the right to demand
that the Company make such issuance and delivery. 
 (e) If a Conversion Shares Depository shall have been appointed, the Conversion
Shares shall initially be registered in the name of the Conversion Shares Depository (which shall hold the Conversion Shares on behalf of the Holders and Beneficial Owners of the Securities), and each Holder

  
 -17- 

 
and Beneficial Owner of the Securities shall be deemed to have irrevocably directed the Company to issue the Conversion Shares corresponding to the conversion of its holding of Securities to the
Conversion Shares Depository (which shall hold the Conversion Shares on behalf of the Holders and Beneficial Owners of the Securities). 

(f) Each Holder and Beneficial Owner of Securities shall be entitled to direct the Conversion Shares Depository to exercise on its behalf
all rights of a holder of the Conversion Shares (including voting rights and rights to receive dividends) other than any right to sell or otherwise transfer the Conversion Shares, which no such Holder or Beneficial Owner shall be entitled to
exercise prior to the delivery of the Conversion Shares to it in accordance with the procedures set forth under Section 4.03. 

(g) The Company’s calculation of its Group CET1 Capital, Group Total Risk Exposure Amount and Group CET1 Ratio, as well as any
Trigger Event Officers’ Certificate delivered to the Trustee, shall be binding on the Trustee and the Holders and Beneficial Owners of the Securities. 

Section 4.02 Conversion Shares. 

(a) The number of Conversion Shares to be issued to the Conversion Shares Depository (or other relevant recipient) upon Conversion will
be the aggregate principal amount of the Securities outstanding immediately prior to Conversion on the Conversion Date divided by the Conversion Price (rounded down, if necessary, to the nearest whole number of Conversion Shares). Each Holder of the
Securities shall be entitled (subject to compliance with the relevant settlement procedures) to receive a number of Conversion Shares from the Conversion Shares Depository (or other relevant initial recipient) equal to the aggregate Tradable Amount
of the Securities held by such Holder divided by the Conversion Price (rounded down, if necessary, to the nearest whole number of Conversion Shares). The Conversion Shares Depository (or other relevant recipient) shall hold the Conversion Shares on
behalf of the Holders of the Securities to the extent of each such Holder’s entitlement to receive Conversion Shares as set forth above. Fractions of Conversion Shares shall not be issued or delivered following a Conversion and no cash payment
shall be made in lieu thereof. 
 (b) The Conversion Shares issued following a Conversion shall be fully paid and non-assessable and shall in all respects rank pari passu with the fully paid Ordinary Shares in issue on the Conversion Date, except in any such case for any right excluded by mandatory provisions of
applicable law, and except that the Conversion Shares so issued shall not rank for (or, as the case may be, the relevant Holder or Beneficial Owner shall not be entitled to receive) any rights, the entitlement to which falls prior to the Conversion
Date. 
 (c) If the Company has an ADS Depositary Facility in effect on the Conversion Date, the Conversion Shares Depository shall
deposit with the ADS Depositary any Conversion Shares in respect of which any Holder or Beneficial Owner of the Securities elects to receive ADSs pursuant to a validly completed Conversion Shares Settlement Notice on the applicable Settlement Date
and shall cause the ADS Depositary to issue the corresponding number of ADSs to such Holder or Beneficial Owner in accordance with its applicable procedures, including with respect to the payment of any applicable fees and expenses of the ADS
Depositary. The obligation to deliver ADSs if a Holder or Beneficial Owner of the Securities elects to have its Conversion Shares delivered in such form will apply only if at the time of Conversion the Company continues to maintain an ADS Depositary
Facility. The delivery of the Conversion Shares to the ADS Depositary shall be deemed for all purposes to constitute the delivery of the Conversion Shares to any such Holder or Beneficial Owner. 

(d) The procedures set forth in Sections 4.01 and 4.02 are subject to change to reflect changes in DTC practices, and the Company may
make changes to the procedures set forth in Sections 4.01 and 4.02 to the extent reasonably necessary, in the opinion of the Company, to reflect such changes in DTC practices. 

  
 -18- 

 Section 4.03 Settlement Procedure. 

(a) Delivery of the Conversion Shares to the Holders and Beneficial Owners of the Securities shall be made in accordance with the
procedures set forth in this Section 4.03. 
 (b) No Holder or Beneficial Owner of the Securities (or the custodian, nominee,
broker or other representative thereof) shall receive delivery of the relevant Conversion Shares unless the Conversion Shares Depository shall have received its Conversion Shares Settlement Notice (and, if required, the Securities to which it
relates) on or before the Notice Cut-Off Date. Any notice or Securities received after the end of normal business hours at the specified office of the Conversion Shares Depository shall be deemed received on
the following Business Day. 
 (c) If the outstanding Securities are then issued in the form of Global Securities, no Conversion Shares
Settlement Notice shall be valid unless given in accordance with the applicable procedures of the Depositary and in a form acceptable to it. If the outstanding Securities are then issued in definitive form, no Conversion Shares Settlement Notice
shall be valid for any purpose unless the Conversion Shares Depository shall have received the Securities to which it relates, duly endorsed to the Conversion Shares Depository. Each Conversion Shares Settlement Notice must be given in a form
acceptable to the Conversion Shares Depository. 
 (d) Subject to any election pursuant to Section 4.02(c) and satisfaction of the
requirements and limitations set forth in this Section 4.03 and provided that the Conversion Shares Settlement Notice and the relevant Securities, if applicable, are delivered on or before the Notice
Cut-Off Date, the Conversion Shares Depository shall deliver the relevant Conversion Shares (rounded down to the nearest whole number of Conversion Shares) to the Holder or Beneficial Owner (or custodian,
nominee, broker or other representative thereof) of the relevant Securities completing the relevant Conversion Shares Settlement Notice in accordance with the instructions given in such Conversion Shares Settlement Notice on the applicable
Settlement Date. 
 (e) Each Conversion Shares Settlement Notice shall be irrevocable. The Conversion Shares Depository shall
determine, in its sole and absolute discretion, whether any Conversion Shares Settlement Notice has been properly completed and delivered, and such determination shall be conclusive and binding on the relevant Holder or Beneficial Owner. If any
Holder or Beneficial Owner of the Securities fails to properly complete and deliver a Conversion Shares Settlement Notice and the relevant Securities, if applicable, prior to the Notice Cut-Off Date, the
Conversion Shares Depository shall be entitled to treat such Conversion Shares Settlement Notice as null and void. 
 (f) Each Security
shall be cancelled on the applicable Cancellation Date. 
 (g) Neither the Company, nor any member of the Group, shall be liable for
any taxes or capital, stamp, issue and registration or transfer taxes or duties arising on Conversion or that may arise or be paid as a consequence of the issue and delivery of Conversion Shares (other than any taxes due by the Company or any member
of the Group according to the Dutch Corporate Income Tax Act 1969 (Wet op de vennootschapsbelasting 1969), which tax shall be borne solely by the Holder or Beneficial Owner of the Securities, or, if different, the person to whom the
Conversion Shares are delivered). 
 Section 4.04 Failure to Deliver a Conversion Shares Settlement Notice. The Conversion
Shares Depository shall continue to hold all Conversion Shares for which it has not received a 

  
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valid Conversion Settlement Notice (and the related Securities, if applicable) on or prior to the Notice Cut-Off Date until the Final Cancellation Date.
Any Holder or Beneficial Owner (or custodian, nominee, broker or other representative thereof) of Securities delivering a Conversion Shares Settlement Notice after the Notice Cut-Off Date shall be required to
provide evidence of its entitlement to the relevant Conversion Shares, satisfactory to the Conversion Shares Depository in its sole and absolute discretion, in order to receive delivery of such Conversion Shares. The Company shall have no liability
to any Holder or Beneficial Owner of the Securities for any loss resulting from such Holder’s or Beneficial Owner’s failure to receive any Conversion Shares, or from any delay in the receipt thereof, in each case as a result of such Holder
or Beneficial Owner (or custodian, nominee, broker or other representative thereof) failing to duly submit a valid Conversion Shares Settlement Notice and the relevant Securities, if applicable, on a timely basis or at all. 

Section 4.05 Adjustment of Floor Price.  

(a) The Floor Price shall be subject to adjustment as set forth in Annex I (Anti-Dilution Provisions). 

(b) There shall at all times any Securities are Outstanding be a conversion calculation agent (the “Conversion Calculation
Agent”), which may be the Company or another Person appointed by the Company to serve in such capacity, who shall be responsible in consultation with the Company for the calculation of all adjustments to the Floor Price to be made pursuant
to Annex I (Anti-Dilution Provisions) and all determinations required to be made pursuant thereto. Determinations, calculations and adjustments performed by the Conversion Calculation Agent pursuant to this Section 4.05(b) shall
be final and binding (in the absence of bad faith or manifest error) on Holders and Beneficial Owners of the Securities. To the extent Annex I (Anti-Dilution Provisions) at any time calls for any calculation or determination to be made
by an Independent Conversion Adviser, if the Person then serving as Conversion Calculation Agent is not wholly independent of the Company, the Company shall use commercially reasonable efforts to appoint an Independent Conversion Adviser to make
such calculation or determination. A written opinion of such Independent Conversion Adviser in respect of such calculation or determination shall be conclusive and binding on the Company and the Holders and Beneficial Owners of the Securities, save
in the case of manifest error. 
 (c) The Company shall give notice of any adjustments to the Floor Price to the Holders of the
Securities, with a copy to the Trustee, and if the Securities are then held in the form of Global Securities shall cause the Depositary to deliver such notice to its participants in accordance with its applicable procedures. 

Section 4.06 Covenants Relating to Conversion Shares. 

(a) For so long as any Security remains Outstanding, the Company shall: 

 

	 	(i)	 not make any issue, grant or distribution or take or omit to take any other action if the effect thereof would
be that, on Conversion, Ordinary Shares could not, under any applicable law then in effect, be legally issued as fully paid; 

  

	 	(ii)	 if any offer is made to all (or as nearly as may be practicable all) shareholders (or all (or as nearly as may
be practicable all) such shareholders other than the offeror and/or any associates of the offeror) to acquire all or a majority of the issued Ordinary Shares, or if a scheme is proposed with regard to such acquisition, give notice of such offer or
scheme to each Holder of any Securities at the same time as any notice thereof is sent to the shareholders (or as soon as practicable thereafter) that details concerning such offer or scheme may be obtained from the specified offices of the Trustee;

  
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	 	(iii)	 use commercially reasonable efforts to ensure that the Ordinary Shares issued upon Conversion shall be admitted
to listing and trading on the Relevant Stock Exchange; 

  

	 	(iv)	 maintain all corporate authorizations necessary to issue and allot at all times sufficient Ordinary Shares,
free from pre-emptive or other preferential rights, to enable Conversion of the Securities to be satisfied in full; 

  

	 	(v)	 use commercially reasonable efforts promptly to appoint a Conversion Shares Depository as soon as practicable
following the occurrence of a Trigger Event; and 

  

	 	(vi)	 If, at the time of a Conversion the Company has an ADS Depositary Facility in effect, the Company shall ensure
that it has sufficient capacity under its then effective registration statement on Form F-6 (or successor form) to cause the ADS Depositary to issue the number of ADSs corresponding to the number of ADSs that
Holders and Beneficial Owners of the Securities have elected to receive pursuant to Section 4.02(c). 

 (b) The
Company shall not be required to comply with any obligation set forth in Section 4.06(a)(i) if its compliance with such obligation would violate the Capital Regulations or (ii) to the extent that such compliance would cause a
Regulatory Event to occur. 
 ARTICLE V 

DUTCH BAIL-IN POWER 

Section 5.01    Agreement and Acknowledgment with Respect to Exercise of Dutch
Bail-in Power. 
 (a) Notwithstanding any other agreements, arrangements or understandings
between the Company and any holder or beneficial owner of the Securities, by acquiring the Securities, each Holder and Beneficial Owner of the Securities or any interest therein acknowledges, accepts, recognizes, agrees to be bound by, and consents
to the exercise of, any Dutch Bail-in Power by the Relevant Resolution Authority that may result in the reduction (including to zero), cancellation or write-down (whether on a permanent basis or subject to write-up by the resolution authority) of all, or a portion, of the principal amount of, or interest on, the Securities and/or the conversion of all, or a portion of, the principal amount of, or interest on, the
Securities into shares or claims which may give right to shares or other instruments of ownership or other securities or other obligations of the Company or obligations of another person (whether or not at the point of
non-viability and independently of or in combination with a resolution action), including by means of a variation to the terms of the Securities (which may include amending the interest amount or the maturity
or interest payment dates, including by suspending payment for a temporary period), or that the Securities must otherwise be applied to absorb losses, or any expropriation of the Securities, in each case, to give effect to the exercise by the
Relevant Resolution Authority of such Dutch Bail-in Power (whether at the point of non-viability or as taken together with a resolution action). Each Holder and
Beneficial Owner of the Securities or any interest therein further acknowledges and agrees that the rights of Holders and Beneficial Owners of the Securities or any interest therein are subject to, and will be varied, if necessary, so as to give
effect to, the exercise of any Dutch 

  
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Bail-in Power by the Relevant Resolution Authority. For the avoidance of doubt, the potential conversion of the Securities into shares, other securities or
other obligations in connection with the exercise of any Dutch Bail-in Power by the Relevant Resolution Authority is separate and distinct from a Conversion following a Trigger Event. In addition, by acquiring
any Securities, each Holder and Beneficial Owner of the Securities or any interest therein further acknowledges, agrees to be bound by, and consents to the exercise by the Relevant Resolution Authority of, any power to vary the terms of the
Securities, which may include amending the Interest Payment Dates or amount, or to suspend any payment in respect of the Securities for a temporary period. 

(b) By its acquisition of the Securities, each Holder and Beneficial Owner: 

 

	 	(i)	 acknowledges and agrees that no exercise of the Dutch Bail-in Power by
the Relevant Resolution Authority with respect to the Securities or cancellation or deemed cancellation of interest on the Securities shall give rise to a default for purposes of the applicable provisions of the U.S. Trust Indenture Act of 1939, as
amended (the “Trust Indenture Act“); 

  

	 	(ii)	 to the extent permitted by the Trust Indenture Act, waives any and all claims against the Trustee for, agrees
not to initiate a suit against the Trustee in respect of, and agrees that the Trustee shall not be liable for, any action that the Trustee takes, or abstains from taking, in either case in accordance with the exercise of the Dutch Bail-in Power by the Relevant Resolution Authority with respect to the Securities; 

  

	 	(iii)	 acknowledges and agrees that, upon the exercise of any Dutch Bail-in
Power by the Relevant Resolution Authority, (i) the Trustee shall not be required to take any further directions from Holders or Beneficial Owners of the Securities under this Fourth Supplemental Indenture and (ii) this Fourth Supplemental
Indenture shall impose no duties upon the Trustee whatsoever with respect to the exercise of any Dutch Bail-in Power by the Relevant Resolution Authority. Notwithstanding the foregoing, if, following the
completion of the exercise of the Dutch Bail-in Power by the Relevant Resolution Authority, the Securities remain outstanding, then the Trustee’s duties under this Fourth Supplemental Indenture shall
remain applicable with respect to the Securities following such completion to the extent that the Company and the Trustee shall agree; and 

  

	 	(iv)	 (i) consents to the exercise of any Dutch Bail-in Power as it may be
imposed without any prior notice by the Relevant Resolution Authority of its decision to exercise such power with respect to the Securities and (ii) authorizes, directs and requests DTC and any direct participant in DTC or other intermediary
through which it holds such Securities to take any and all necessary action, if required, to implement (x) the Conversion and (y) the exercise of any Dutch Bail-in Power with respect to the
Securities as it may be imposed, without any further action or direction on the part of such Holder or such Beneficial Owner. 

(c) By its acquisitions of the Securities, each Holder and Beneficial Owner:  

 

	 	(i)	 consents to the Conversion of its Securities following a Trigger Event and consents to the appointment of the
Conversion Shares Depository and the issuance of the Conversion Shares to the Conversion Shares Depository, all of which may occur without any further action on the part of such Holder or

  
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Beneficial Owner or the Trustee. To the extent the Securities are held in the form of global securities, such Holder or Beneficial Owner authorizes, directs and requests DTC, any direct
participant therein and any other intermediary through which it holds such Securities to take any and all necessary action, if required, to implement the Conversion without any further action or direction on the part of such Holder or Beneficial
Owner or the Trustee. 

  

	 	(ii)	 acknowledges and agrees that (a) interest is payable solely at the discretion of the Company, and no
amount of interest shall become due and payable in respect of the relevant Interest Payment Date or related Interest Period or redemption date to the extent that it has been cancelled or deemed cancelled (in whole or in part) by the Company in its
sole discretion and/or as a result of (i) the Company having insufficient Distributable Items, (ii) the relevant interest payment’s causing the Maximum Distributable Amount to be exceeded, or (iii) a Trigger Event or a
Liquidation Event having occurred; and (b) a cancellation or deemed cancellation of interest (in each case, in whole or in part) in accordance with the terms of this Fourth Supplemental Indenture shall not constitute a default in payment or
otherwise under the terms of the Securities. 

  

	 	(iii)	 unconditionally and irrevocably agrees to each and every provision of this Fourth Supplemental Indenture and
the Securities and waives, to the fullest extent permitted by the Trust Indenture Act and any other applicable law, any and all claims against the Trustee arising out of its acceptance of its trusteeship for the Securities, including, without
limitation, claims related to or arising out of or in connection with a Trigger Event and/or any Conversion. 

  

	 	(iv)	 acknowledges and agrees that all authority conferred or agreed to be conferred by any Holder or Beneficial
Owner pursuant to the provisions described above shall be binding upon the successors, assigns, heirs, executors, administrators, trustees in bankruptcy and legal representatives of each Holder or Beneficial Owner of a Security or any interest
therein. 

 (d) No repayment of the principal amount of the Securities or payment of interest on the Securities shall be
come due and payable after the exercise of any Dutch Bail-in Power by the Relevant Resolution Authority unless such repayment or payment would be permitted to be made by the Company under the laws and
regulations of The Netherlands and the European Union applicable to the Company. 
 (e) Upon the exercise of the Dutch Bail-in Power by the Relevant Resolution Authority with respect to the Securities, the Company shall provide a written notice of such event to DTC (if the Securities are then held by DTC in the form of Global
Securities) for the purposes of notifying Holders of Securities of such occurrence, including the amount of any cancellation of all, or a portion, of the principal amount of, or interest on, the Securities, with a copy to the Trustee for information
purposes, as soon as practicable regarding such exercise of the Dutch Bail-in Power. Failure to provide such notices will not have any impact on the effectiveness of, or otherwise invalidate, any such exercise
of the Dutch Bail-in Power. 
 (f) Holders or Beneficial Owners of Securities that acquire them in
the secondary market shall be deemed to acknowledge, agree to be bound by and consent to the same provisions specified herein to the same extent as the Holders or Beneficial Owners of the Securities that acquire the Securities upon their initial
issuance, including, without limitation, with respect to the acknowledgement and agreement to be bound by and consent to the terms of the Securities, including in relation to interest cancellation, the Conversion, the Dutch Bail-in Power and the limitations on remedies specified in Article VI hereof. 

  
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 ARTICLE VI 

DEFAULTS AND REMEDIES 

The following provisions shall apply to the Securities in lieu of Sections 5.01 and 5.02 of the Base Indenture and in addition to the other
provisions set forth in Article 5 of the Base Indenture: 
 Section 6.01 Liquidation Event. A Liquidation Event occurring
prior to the occurrence of a Trigger Event shall be the sole Event of Default with respect to the Securities. The principal amount of the Securities shall become immediately due and payable upon an Event of Default with respect to the Securities,
without the need of any further action on the part of the Trustee, the Holders of the Securities or any other Person. 

Section 6.02 Failure to Pay Principal Amount. Any Holder of a Security (or the Trustee acting on behalf of all
Holders of the Securities) may demand payment of the principal amount of the Securities upon a Payment Default. The Trustee may, at its discretion, in such event institute bankruptcy proceedings in The Netherlands (or such other jurisdiction in
which the Company may be organized) (but not elsewhere) against the Company and/or prove in a bankruptcy or liquidation of the Company and/or claim in a liquidation or administration of the Company. 

Section 6.03 Performance Obligations. The Trustee may without further notice institute such proceedings against the Company as it
may deem fit to enforce or seek damages for the breach of any Performance Obligation. 
 Section 6.04 No Other Remedies and Other
Terms. 
 (a) Other than the limited remedies specified in this Article VI, and subject to Section 6.04(c), no remedy against
the Company shall be available to the Trustee (acting on behalf of the Holders of the Securities) or to any Holder or Beneficial Owner of the Securities, whether for the recovery of amounts owing in respect of such Securities or under the Indenture,
or in respect of any breach by the Company of any of the Company’s obligations under or in respect of the terms of such Securities or under the Indenture in relation thereto; provided that the Company’s obligations to the
Trustee under Section 6.07 of the Base Indenture and the Trustee’s rights to have money collected applied first to pay amounts due to it under such Section pursuant to Section 5.06 of the Base Indenture expressly survive any Default
and are not subject to the subordination provisions of Article VII of this Fourth Supplemental Indenture. 
 (b) In the case of a Default
under the Securities, the Trustee shall exercise such of the rights and powers vested in it by the Indenture, and use the same degree of care and skill in their exercise, as a prudent person would exercise or use under the circumstances in the
conduct of his or her own affairs. For purposes of the Base Indenture, “Event of Default” in respect of the Securities shall mean “Default” as defined in this Fourth Supplemental Indenture, except that the term “Event of
Default” as used in Section 3.05(b)(ii) of the Base Indenture and Article 8 of the Base Indenture shall mean “Liquidation Event.” 

(c) Notwithstanding the limitations on remedies specified under Article VI, (i) the Trustee shall have such powers as are required to be
authorized to it under the Trust Indenture Act in 

  
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respect of the rights of the Holders and Beneficial Owners of the Securities under the provisions of the Indenture, and (ii) nothing shall impair the right of a Holder or Beneficial Owner of
the Securities under the Trust Indenture Act, absent such Holder’s or Beneficial Owner’s consent, to sue for any payment due but unpaid with respect to the Securities; provided that, in the case of (i) and (ii) above, any
payments in respect of, or arising from, the Securities, including any payments or amounts resulting or arising from the enforcement of any rights under the Trust Indenture Act in respect of the Securities, shall be subject to the subordination
provisions set forth in Section 7.01 of this Fourth Supplemental Indenture. 
 Section 6.05 Waiver of Past Defaults.

 (a) Holders of not less than a majority in aggregate principal amount of the Outstanding Securities may on behalf of the Holders of
all of the Securities waive any past Default that results from a breach by the Company of a Performance Obligation. Holders of a majority of the aggregate principal amount of the Outstanding Securities shall not be entitled to waive any past default
that results from a Liquidation Event or a Payment Default. 
 (b) Upon the occurrence of any waiver permitted by Section 6.05(a), such
Default shall cease to exist, and any Default with respect to any series arising therefrom shall be deemed to have been cured and not to have occurred for every purpose of the Base Indenture, but no such waiver shall extend to any subsequent or
other Default or impair any right consequent thereon. 
 ARTICLE VII 

SUBORDINATION AND SET-OFF 

Section 7.01 Subordination. 

(a) The Securities shall constitute the Company’s direct, unsecured and subordinated obligations, ranking equally without any
preference among themselves and at least pari passu with all other present and future unsecured and subordinated obligations of the Issuer, save for those that have been accorded by law preferential rights (including as a result of the
Amending Act). The rights and claims of the Holders and Beneficial Owners of the Securities in respect of or arising from the Securities shall be subordinated to the claims of holders of Senior Instruments. 

(b) If a Liquidation Event occurs prior to a Trigger Event, the Securities shall be subordinated to Senior Instruments, and rank pari
passu with all Parity Instruments. By virtue of such subordination, any payments to the Holders of the Securities upon any Liquidation Event shall only be made after all payment obligations of the Company in respect of Senior Instruments have
been satisfied. The amount of any claim in respect of each Security shall be its principal amount. 
 (c) If a Liquidation Event occurs
after a Trigger Event but before the Conversion Shares deliverable upon Conversion are issued and delivered pursuant to Section 4.01, each Holder or Beneficial Owner of a Security shall have a claim, in lieu of any other payment by the Company,
for the amount, if any, it would have been entitled to receive if the Conversion relating to such Trigger Event and the relevant number of Conversion Shares to which such holder would have been entitled had been delivered to such holder had occurred
immediately prior to the Liquidation Event. 
 (d) From (and including) the Effective Date, the Securities are intended to qualify as, and
comprise part of, own funds having a lower priority ranking than any claim that does not result from an own funds item within the meaning of the Amending Act. 

  
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 Section 7.02 No Set-Off. Subject
to applicable law, neither any no Holder or Beneficial Owner of Securities, nor the Trustee acting on their behalf, may exercise, claim or plead any right of set-off, compensation or retention in respect of
any amount owed to it by the Company in respect of or arising under, or in connection with, the Securities or the Indenture and each Holder and Beneficial Owner of Securities, by virtue of its holding of any Securities, and the Trustee acting on
their behalf, shall be deemed to have waived all such rights of set-off, compensation or retention. If notwithstanding the foregoing any amounts due and payable to any Holder or Beneficial Owner of Securities
by the Company in respect of, or arising under, the Securities are discharged by set-off, such Holder or Beneficial Owner shall, subject to applicable law, immediately pay an amount equal to the amount of such
discharge to the Company (or, if a Liquidation Event shall have occurred, the liquidator or administrator of the Company, as the case may be) and, until such time as payment is made, shall hold an amount equal to such amount in trust or otherwise
for the Company (or the liquidator or administrator of the Company, as the case may be) and, accordingly, any such discharge shall be deemed not to have taken place. The foregoing shall not prevent any set-off
in order to give effect to a Conversion. 
 ARTICLE VIII 

ADDITIONAL TRUSTEE PROTECTIONS 

Section 8.01 Conversion. Notwithstanding anything to the contrary contained in the Indenture or the Securities, 

(a) once the Company has delivered a Conversion Notice, (i) no Holder or Beneficial Owner of a Security shall have any rights whatsoever
under the Indenture or the Securities to instruct or direct the Trustee to take any action whatsoever and (ii) as of the date of the Conversion Notice, except for any indemnity and/or security provided by any Holder or by any Beneficial Owner
of the Securities in such direction or related to such direction, any direction previously given to the Trustee by any Holders or by any Beneficial Owners of the Securities shall cease automatically and shall be null and void and of no further
effect; except in each case of (i) and (ii) of this Section, with respect to any rights of Holders or Beneficial Owners of the Securities with respect to any payments under the Securities that were unconditionally due and payable prior to the
date of the Conversion Notice or unless the Trustee is instructed in writing by the Company to act otherwise; 
 (b) the Trustee shall be
entitled to conclusively rely on and accept a Trigger Event Officers’ Certificate without any duty whatsoever of further inquiry as sufficient and conclusive evidence of the occurrence of a Trigger Event, and such Trigger Event Officers’
Certificate shall be conclusive and binding on the Trustee and each Holder and Beneficial Owner of any Security or interest therein; and 

(c) the Trustee shall not be liable with respect to (i) the calculation or accuracy of the Group CET1 Capital, Group Total Risk Exposure
Amount and Group CET1 Ratio in connection with the occurrence of a Trigger Event and the timing of such Trigger Event, (ii) the failure of the Company to provide any information whatsoever in respect of a Trigger Event to any Holder or
Beneficial Owner of a Security, (iii) any aspect of the Company’s decision to deliver a Conversion Notice or the related Conversion or (iv) the adequacy of the disclosure of these provisions to any Holder or Beneficial Owner of any
Security or any interest therein or for the direct or indirect consequences thereof. 

  
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 Section 8.02 Indemnification by the Company. The Company’s
obligations to indemnify the Trustee in accordance with Section 6.07 of the Base Indenture shall survive any exercise of the Dutch Bail-in Power by the Relevant Resolution Authority with respect to the
Securities and any Conversion hereunder. 
 ARTICLE IX 

ADDITIONAL ACKNOWLEDGEMENTS AND AGREEMENTS 

OF HOLDERS AND BENEFICIAL OWNERS 

By acquiring the Securities, each Holder and Beneficial Owner of a Security or any interest therein, including any Person acquiring any such
Security or interest therein after the date hereof, acknowledges and agrees with and for the benefit of the Company and the Trustee as follows: 

Section 9.01 Dutch Bail-in Power. Such Holder and Beneficial Owner of a Security or
any interest therein: 
 (a) acknowledges and agrees that no exercise of the Dutch Bail-in Power by
the Relevant Resolution Authority with respect to the Securities or cancellation or deemed cancellation of interest on the Securities pursuant to Sections 2.03 and 2.04 shall give rise to a default for purposes of Section 315(b) (Notice of
Default) and Section 315(c) (Duties of the Trustee in Case of Default) of the Trust Indenture Act; 
 (b) to the extent permitted by
the Trust Indenture Act, waives any and all claims against the Trustee for, agrees not to initiate a suit against the Trustee in respect of, and agrees that the Trustee shall not be liable for, any action that the Trustee takes, or abstains from
taking, in either case in accordance with the exercise of the Dutch Bail-in Power by the Relevant Resolution Authority with respect to the Securities; 

(c) acknowledges and agrees that, upon the exercise of any Dutch Bail-in Power by the Relevant
Resolution Authority, (i) the Trustee shall not be required to take any further directions from Holders or Beneficial Owners of the Securities under Section 5.12 of the Base Indenture and (ii) the Indenture shall impose no duties upon
the Trustee whatsoever with respect to the exercise of any Dutch Bail-in Power by the Relevant Resolution Authority. If Holders or Beneficial Owners of the Securities have given a direction to the Trustee
pursuant to Section 5.12 of the Base Indenture prior to the exercise of any Dutch Bail-in Power by the Relevant Resolution Authority, such direction shall cease to be of further effect upon such exercise
of any Dutch Bail-in Power and shall become null and void at such time. Notwithstanding the foregoing, if, following the completion of the exercise of the Dutch Bail-in
Power by the Relevant Resolution Authority, the Securities remain outstanding, then the Trustee’s duties under the Indenture shall remain applicable with respect to the Securities following such completion to the extent that the Company and the
Trustee shall agree pursuant to a supplemental indenture or an amendment to this Fourth Supplemental Indenture; and 
 (d) (i) consents to
the exercise of any Dutch Bail-in Power as it may be imposed without any prior notice by the Relevant Resolution Authority of its decision to exercise such power with respect to the Securities and
(ii) authorizes, directs and requests DTC and any direct participant in DTC or other intermediary through which it holds such Securities to take any and all necessary action, if required, to implement (x) the Conversion and (y) the
exercise of any Dutch Bail-in Power with respect to the Securities as it may be imposed, without any further action or direction on the part of such Holder and such Beneficial Owner. 

  
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 Section 9.02 Conversion Upon a Trigger Event. Such Holder or Beneficial
Owner consents to the Conversion of its Securities following a Trigger Event, the appointment of the Conversion Shares Depository, and the issuance of the Conversion Shares to the Conversion Shares Depository, all of which may occur without any
further action on the part of such Holder or Beneficial Owner or the Trustee, and following which no Holder or Beneficial Owner of any Securities will have any rights against the Company with respect to the payment of principal of, or interest on,
such Securities. To the extent the Securities are held in the form of Global Securities, such Holder or Beneficial Owner authorizes, directs and requests the Depositary, any direct participant therein and any other intermediary through which it
holds such Securities to take any and all necessary action, if required, to implement the Conversion without any further action or direction on the part of such Holder or Beneficial Owner or the Trustee. Upon a Trigger Event and Conversion, the
principal amount of the Securities may be applied in such manner as the Company deems necessary in connection with the issue and paying up of the relevant Conversion Shares and the delivery thereof to the Conversion Shares Depository or pursuant to
any Alternative Delivery Arrangements. 
 Section 9.03 Interest Cancellation. Interest shall be payable on the
Securities solely at the discretion of the Company, and no amount of interest shall become due and payable in respect of the relevant Interest Payment Date or related Interest Period or Redemption Date to the extent that it has been cancelled or
deemed cancelled (in whole or in part) by the Company in its sole discretion and/or as a result of (i) the Company having insufficient Distributable Items, (ii) the relevant interest payment’s causing the Maximum Distributable Amount
to be exceeded, or (iii) a Trigger Event or a Liquidation Event having occurred. A cancellation or deemed cancellation of interest (in each case, in whole or in part) in accordance with the terms of the Indenture shall not constitute a default
in payment or otherwise under the terms of the Securities. 
 Section 9.04 Waiver of Claims. Such Holder or Beneficial
Owner unconditionally and irrevocably agrees to each and every provision of the Indenture and the Securities and waives, to the fullest extent permitted by the Trust Indenture Act and any other applicable law, any and all claims against the Trustee
arising out of its acceptance of its trusteeship for the Securities, including, without limitation, claims related to or arising out of or in connection with a Trigger Event and/or any Conversion. 

Section 9.05 Successors and Assigns. All authority conferred or agreed to be conferred by any Holder or Beneficial
Owner of the Securities pursuant to this Article IX shall be binding upon the successors, assigns, heirs, executors, administrators, trustees in bankruptcy and legal representatives of such Holder or Beneficial Owner. 

ARTICLE X 

ADDITIONAL AMOUNTS 

Section 10.01 Additional Amounts. 

(a) All amounts of principal of, and any premium and interest on, the Securities will be paid by the Company or any successor thereof
without deduction or withholding for any taxes, assessments or other charges imposed by the government of The Netherlands, or the government of a jurisdiction in which a successor to the Company is organized or resident for tax purposes, unless such
deduction or withholding is required by applicable law. If deduction or withholding of any of these charges is required by The Netherlands, or by a jurisdiction in which a successor to the Company is organized or resident for tax purposes, the
Company or such successor, as the case may be, will pay as additional interest any additional amounts necessary to make the net amount paid to the affected Holders 

  
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equal the amount the Holders would have received in the absence of the deduction or withholding. However, additional amounts will not be paid for: 

 

	 	•	 	 the amount of any tax, assessment or other governmental charge imposed by any taxing authority of or in the
United States; 

  

	 	•	 	 the amount of any withholding or deduction that will be required to be made pursuant to the Dutch Withholding Tax
Act 2021 (Wet bronbelasting 2021); 

  

	 	•	 	 the amount of any tax, assessment or other governmental charge which is only payable because:

  

	 	•	 	 a connection, other than the holding or ownership of the capital security or the receipt of interest and
principal thereon, exists between the Holder and The Netherlands (or such jurisdiction in which a successor to the Company is organized or resident for tax purposes); 

 

	 	•	 	 the Holder presented the capital security for payment (where presentation is required) more than 15 days after
the date on which the relevant payment became due or was provided for, whichever is later; 

  

	 	•	 	 the Holder failed to comply, on a timely basis, with a written request of the Company or any successor thereof
for any applicable information or certification that would have, if provided on a timely basis, permitted the payment to be made without withholding or deduction (or with a reduced rate of withholding or deduction); 

 

	 	•	 	 the amount of any estate, inheritance, gift, sales, excise, transfer or personal property tax or any similar tax,
duty, assessment or governmental charge; 

  

	 	•	 	 the amount of any tax, assessment or other governmental charge which is payable other than by deduction or
withholding from a payment on or in respect of the capital securities; 

  

	 	•	 	 the amount of any tax, assessment or other governmental charge that a Holder or Beneficial Owner would have been
able to avoid (but has not so avoided) by presenting and surrendering the relevant capital security to another paying agent (where presentation and surrendering is required); 

 

	 	•	 	 the amount of any tax, assessment or other governmental charge which is payable by any person acting as custodian
bank or collecting agent on behalf of a Holder, or otherwise in any manner which does not constitute a withholding or deduction by the Company, the Paying Agent or any successor thereof from payments made by it; 

 

	 	•	 	 the amount of any tax, assessment or other governmental charge which is withheld or deducted by a paying agent
from a payment if the payment could have been made by another paying agent without such withholding or deduction; 

  

	 	•	 	 the amount of any tax, assessment or other governmental charge which is payable by reason of a change in law that
becomes effective more than 30 days after the relevant payment becomes due and is made available for payment to the Holders, unless such tax, assessment or other governmental charge would have been applicable had payment been made within such 30 day
period; or 

  
 -29- 

	 	•	 	 any combination of the taxes, assessments or other governmental charges described above. 

In addition, the Company will not pay “additional amounts” to a Holder that is a fiduciary or partnership or an entity that is not the sole
Beneficial Owner of the payment where the law requires the payment to be included in the income of a beneficiary or settlor for tax purposes with respect to such fiduciary or a member of such partnership or a Beneficial Owner who would not have been
entitled to such “additional amounts” had it been the Holder. Whenever in this Indenture there is mentioned, in any context, the payment of the principal of (and premium, if any) or any interest, if any, on or in respect of any Capital
Security of any series, such mention shall be deemed to include mention of the payment of Additional Amounts provided for in this Section to the extent that, in such context, Additional Amounts are, were or would be payable in respect thereof
pursuant to the provisions of this Section and as if express mention of the payment of Additional Amounts (if applicable) were made in any provisions hereof where such express mention is not made. 

(b) Additional Amounts shall only be paid in the event that deduction or withholding relates to interest payments (and not payments of
principal), and subject to the restrictions contained in Section 2.04 above. 
 ARTICLE XI 

AMENDMENTS TO THE INDENTURE 

Section 11.01 Supplemental Indentures Without Consent of Holders. 

(a) The first paragraph of Section 3.03 of the Base Indenture is hereby amended and restated in its entirety to read as follows: 

“The Capital Securities shall be executed on behalf of the Company by a Chairman of the Executive Board, a Vice Chairman
of the Executive Board, any member of the Executive Board, or the Chief Financial Officer of the Company (or any other officer of the Company designated in writing by or pursuant to authority of the Executive Board and delivered to the Trustee from
time to time). The signature of any of these officers on the Capital Securities may be manual, facsimile or electronic. Capital Securities bearing the manual, facsimile or electronic signatures of individuals who were at any time the proper officers
of the Company shall bind the Company, notwithstanding that such individuals or any of them have ceased to hold such offices prior to the authentication and delivery of such Capital Securities.” 

(b) The fifth paragraph of Section 3.03 of the Base Indenture is hereby amended and restated in its entirety to read as follows: 

“No Capital Security shall be entitled to any benefit under this Indenture or be valid or obligatory for any purpose
unless there appears on such Capital Security a certificate of authentication substantially in the form provided for herein executed by or on behalf of the Trustee by manual or electronic signature, and such certificate upon any Capital Security
shall be conclusive evidence, and 

  
 -30- 

 
the only evidence, that such Capital Security has been duly authenticated and delivered hereunder and that such Capital Security is entitled to the benefits of this Indenture. Notwithstanding the
foregoing, if any Capital Security shall have been authenticated and delivered hereunder but never issued and sold by the Company, and the Company shall deliver such Capital Security to the Trustee for cancellation as provided in Section 3.09,
for all purposes of this Indenture such Capital Security shall be deemed never to have been authenticated and delivered hereunder and shall never be entitled to the benefits of this Indenture.” 

ARTICLE XII 

MISCELLANEOUS PROVISIONS 

Section 12.01 Effectiveness. This Fourth Supplemental Indenture shall become effective upon its execution and delivery.

 Section 12.02 Modification. 

(a) Without the consent of any Holders of the Securities, the Company and the Trustee may make such modifications to the provisions of
Sections 4.01 and 4.03 and Exhibits B and C as are reasonably necessary, in the opinion of the Company, to reflect the procedures of the Depositary in effect at the time of any Conversion or issuance of the Securities in definitive form and the
requirements of the Conversion Shares Depository. 
 (b) Any modification to or waiver of Section 4.06 shall require the consent of the
Holders of at least 75% in principal amount of the outstanding Securities. 
 (c) Any amendment or modification of the Securities (or of the
Indenture with respect to the Securities) shall be subject to the Company obtaining the prior written consent of the Competent Authority. 

(d) The Company may not amend Section 7.01 to alter the subordination of any outstanding Securities without the consent of each holder of
any Senior Instrument then outstanding who would be adversely affected. 
 (e) The Company may not amend Section 7.01 in a manner that
would adversely affect the other Capital Securities of any one or more series then outstanding in any material respect, without the consent of the Holders of a majority in aggregate principal amount of all affected series then outstanding, voting
together as one class (and also of any affected series that by its terms is entitled to vote separately as a series). 
 Section 12.03
Original Issue. The Securities may, upon execution of this Fourth Supplemental Indenture, be executed by the Company and delivered by the Company to the Trustee for authentication, and the Trustee shall, upon delivery of a Company
Order, authenticate and deliver such Securities as in such Company Order provided. 
 Section 12.04 Ratification and Integral
Part. The Base Indenture as supplemented by this Fourth Supplemental Indenture, is in all respects ratified and confirmed, including without limitation all the rights, immunities and indemnities of the Trustee, and this Fourth
Supplemental Indenture shall be deemed an integral part of the Base Indenture in the manner and to the extent herein and therein provided. 

  
 -31- 

 Section 12.05 Priority. This Fourth Supplemental Indenture shall be
deemed part of the Base Indenture in the manner and to the extent herein and therein provided. The provisions of this Fourth Supplemental Indenture shall, with respect to the Securities and subject to the terms hereof, supersede the provisions of
the Base Indenture to the extent the Base Indenture is inconsistent herewith. 
 Section 12.06 Successors and
Assigns. All covenants and agreements in the Base Indenture, as supplemented and amended by this Fourth Supplemental Indenture, by the Company shall bind its successors and assigns, whether so expressed or not. 

Section 12.07 Counterparts. This Fourth Supplemental Indenture may be executed in any number of counterparts, each of which
so executed shall be deemed to be an original, but all such counterparts shall together constitute but one and the same instrument. The words “executed”, “signed”, “signature” and words of like
import in this Fourth Supplemental Indenture relating to the execution and delivery of this Fourth Supplemental Indenture and any documents to be delivered in connection herewith shall be deemed to include signatures by Electronic Means, which shall
be of the same legal effect, validity or enforceability as a manually executed signature to the extent and as provided in any applicable law, including the Federal Electronic Signatures in Global and National Commerce Act, the New York State
Electronic Signatures and Records Act, or any other similar state laws based on the Uniform Electronic Transactions Act. 

“Electronic Means” shall mean the following communications methods: e-mail, facsimile
transmission, secure electronic transmission containing applicable authorization codes, passwords and/or authentication keys issued by the Trustee, or another method or system specified by the Trustee as available for use in connection with its
services hereunder. 
 The Trustee shall have the right to accept and act upon instructions, including funds transfer instructions
(“Instructions”) given pursuant to this Indenture and related financing documents and delivered using Electronic Means; provided, however, that the Company and/or the Obligor, as applicable, shall provide to the Trustee an
incumbency certificate listing officers with the authority to provide such Instructions (“Authorized Officers”) and containing specimen signatures of such Authorized Officers, which incumbency certificate shall be amended by the
Company and/or the Obligor, as applicable, whenever a person is to be added or deleted from the listing. If the Company and/or the Obligor, as applicable, elects to give the Trustee Instructions using Electronic Means and the Trustee in its
discretion elects to act upon such Instructions, the Trustee’s understanding of such Instructions shall be deemed controlling. The Company and the Obligor understand and agree that the Trustee cannot determine the identity of the actual
sender of such Instructions and that the Trustee shall conclusively presume that directions that purport to have been sent by an Authorized Officer listed on the incumbency certificate provided to the Trustee have been sent by such Authorized
Officer. The Company and the Obligor shall be responsible for ensuring that only Authorized Officers transmit such Instructions to the Trustee and that the Company, the Obligor and all Authorized Officers are solely responsible to safeguard the
use and confidentiality of applicable user and authorization codes, passwords and/or authentication keys upon receipt by the Company and/or the Obligor, as applicable. The Trustee shall not be liable for any losses, costs or expenses arising
directly or indirectly from the Trustee’s reliance upon and compliance with such Instructions notwithstanding such directions conflict or are inconsistent with a subsequent written instruction. The Company and the Obligor agree:
(i) to assume all risks arising out of the use of Electronic Means to submit Instructions to the Trustee, including without limitation the risk of the Trustee acting on unauthorized Instructions, and the risk of interception and misuse by third
parties; (ii) that it is fully informed of the protections and risks associated with the various methods of transmitting Instructions to the Trustee and that there may be more secure methods of transmitting Instructions than the method(s)
selected by the Company and/or the Obligor, as applicable; (iii) that the security procedures (if any) to be followed in connection with its transmission of Instructions provide to it a commercially reasonable degree of protection in light of
its particular needs and circumstances; and (iv) to notify the Trustee immediately upon learning of any compromise or unauthorized use of the security procedures. 

  
 -32- 

 Section 12.08 Governing Law. This Fourth Supplemental Indenture and the
Securities shall be governed by and construed in accordance with the laws of the State of New York, except for the subordination provisions and the waiver of set-off provisions in Article VII, which are
governed by, and construed in accordance with, Dutch law. 

  
 -33- 

 IN WITNESS WHEREOF, the parties hereto have caused this Fourth Supplemental Indenture to be
duly executed, all as of the day and year first above written. 
  

			
	ING GROEP N.V.
		
	By:	 	 /s/ P.G. van der Linde

		 	Name: P.G. van der Linde
		 	Title: Senior Legal Counsel
		
	By:	 	 /s/ K.I.D. Tuinstra

		 	Name: K.I.D. Tuinstra
		 	Title: Senior Associate Capital Markets
	
	THE BANK OF NEW YORK MELLON, LONDON BRANCH, AS TRUSTEE
		
	By:	 	 /s/ Michael Lee

		 	Name: Michael Lee
		 	Title: Authorized Signatory

  
 Signature Page to the
Fourth Supplemental Indenture 

 Annex I 

Anti-Dilution Provisions 

Adjustment of Floor Price 

Upon the happening of any of the events described below, the Floor Price shall be adjusted as follows: 

 

	 	(i)	 If and whenever there shall be a consolidation, reclassification/redesignation or subdivision affecting the
number of Ordinary Shares, the Floor Price shall be adjusted by multiplying the Floor Price in force immediately prior to such consolidation, reclassification/redesignation or subdivision by the following fraction: 

 

					
		 	  A 
	 	
		 	 B 	 	

 where: 
  

	 	A	 is the aggregate number of Ordinary Shares in issue immediately before such consolidation,
reclassification/redesignation or subdivision, as the case may be; and 

  

	 	B	 is the aggregate number of Ordinary Shares in issue immediately after, and as a result of, such consolidation,
reclassification/redesignation or subdivision, as the case may be. 

 Such adjustment shall become effective on the date
the consolidation, reclassification/redesignation or subdivision, as the case may be, takes effect. 
  

	 	(ii)	 If and whenever the Company shall issue any of its Ordinary Shares credited as fully paid to the Company’s
shareholders by way of capitalization of profits or reserves (including any share premium account or capital redemption reserve) other than (1) where any such Ordinary Shares are or are to be issued instead of the whole or part of a Cash
Dividend which the Shareholders would or could otherwise have elected to receive, (2) where the Company’s shareholders may elect to receive a Cash Dividend in lieu of such Ordinary Shares or (3) where any such Ordinary Shares are or
are expressed to be issued in lieu of a Dividend (whether or not a Cash Dividend equivalent or amount is announced or would otherwise be payable to Shareholders, whether at their election or otherwise), the Floor Price shall be adjusted by
multiplying the Floor Price in force immediately prior to such issue by the following fraction: 

  

					
		 	  A 
	 	
		 	 B 	 	

 where: 
  

	 	A	 is the aggregate number of Ordinary Shares in issue immediately before such issue; and 

 

	 	B	 is the aggregate number of Ordinary Shares in issue immediately after such issue. 

  
 I-1 

 Annex I 
  

 Such adjustment shall become effective on the first date of issue of such Ordinary Shares.

  

	 	(iii)	 

  

	 	(A)	 If and whenever the Company shall pay any Extraordinary Dividend to its shareholders, the Floor Price shall be
adjusted by multiplying the Floor Price in force immediately prior to the Effective Date by the following fraction: 

  

					
		 	  A – B 
	 	
		 	 A – C 	 	

 where: 
  

	 	A	 is the Current Market Price of one ordinary share on the Effective Date; 

 

	 	B	 is the portion of the Fair Market Value of the aggregate Extraordinary Dividend attributable to one ordinary
share, with such portion being determined by dividing the Fair Market Value of the aggregate Extraordinary Dividend by the number of Ordinary Shares entitled to receive the relevant Dividend; and 

 

	 	C	 is an amount equal to: 

 

	 	(a)	 in the case of an Extraordinary Dividend falling under part (i) of the definition of Extraordinary
Dividend, zero; or, 

  

	 	(b)	 in the case of an Extraordinary Dividend falling under part (ii) of the definition of Extraordinary
Dividend, the amount (if any) by which the Reference Amount in respect of the Relevant Year exceeds an amount equal to the aggregate of the Fair Market Values of any previous Cash Dividends (other than any Cash Dividends falling under part
(i) of the definition of Extraordinary Dividend) per ordinary share of the Company paid or made in respect of such Relevant Year (where C shall equal zero if such previous Cash Dividends per ordinary share of the Company are equal to, or
exceed, the Reference Amount in respect of the Relevant Year). For the avoidance of doubt, “C” shall equal the Reference Amount determined in respect of the Relevant Year where no previous Cash Dividends (other than any Cash Dividends
falling under part (i) of the definition of Extraordinary Dividend) per ordinary share of the Company have been paid or made in respect of such Relevant Year. 

Such adjustment shall become effective on the Effective Date or, if later, the first date upon which the Fair Market Value of the relevant
Extraordinary Dividend can be determined. 
 “Effective Date” means, for purposes of this paragraph (iii)(A), the first
date on which the Ordinary Shares are traded ex-the relevant Cash Dividend on the Relevant Stock Exchange. 
  

	 	(B)	 If and whenever the Company shall pay or make any Non-Cash Dividend to
its shareholders, the Floor Price shall be adjusted by multiplying the Floor Price in force immediately prior to the Effective Date by the following fraction: 

 

					
		 	  A – B 
	 	
		 	 A 	 	

  
 I-2 

 Annex I 
  

 where: 
  

	 	A	 is the Current Market Price of one ordinary share on the Effective Date; and 

 

	 	B	 is the portion of the Fair Market Value of the aggregate Non-Cash
Dividend attributable to one ordinary share, with such portion being determined by dividing the Fair Market Value of the aggregate Non-Cash Dividend by the number of Ordinary Shares entitled to receive the
relevant Non-Cash Dividend (or, in the case of a purchase, redemption or buy back of Ordinary Shares or any depositary or other receipts or certificates representing Ordinary Shares by or on behalf of the
Company or any member of the Group, by the number of Ordinary Shares in issue immediately following such purchase, redemption or buy back, and treating as not being in issue any Ordinary Shares, or any Ordinary Shares represented by depositary or
other receipts or certificates, purchased, redeemed or bought back). 

 Such adjustment shall become effective on the
Effective Date or, if later, the first date upon which the Fair Market Value of the relevant Non-Cash Dividend can be determined as provided herein. 

“Effective Date” means, for purposes of this paragraph (iii)(B), the first date on which the Ordinary Shares are traded ex-the relevant Dividend on the Relevant Stock Exchange or, in the case of a purchase, redemption or buy back of Ordinary Shares or any depositary or other receipts or certificates representing Ordinary Shares by or
on behalf of the Company or any member of the Group, the date on which such purchase, redemption or buy back is made (or, in any such case if later, the first date upon which the Fair Market Value of the relevant Dividend is capable of being
determined as provided herein) or in the case of a Spin-Off, the first date on which the Ordinary Shares are traded ex-the relevant
Spin-Off on the Relevant Stock Exchange. 
  

	 	(C)	 For the purposes of this paragraph (iii) and the definition of “Extraordinary Dividend”, the
Fair Market Value of any Cash Dividend or Non-Cash Dividend shall (subject as provided in paragraph (i) of the definition of “Dividend” and in the definition of “Fair Market Value”) be
determined as at the Effective Date of such Cash Dividend, or, as the case may be, Non-Cash Dividend. 

  

	 	(D)	 In making any calculations for the purposes of this paragraph (iii), such adjustments (if any) shall be made as
an Independent Conversion Adviser may determine in good faith to be appropriate to reflect (i) any consolidation or sub-division of any Ordinary Shares or (ii) the issue of Ordinary Shares by way of capitalization of profits or reserves
(or any like or similar event) or (iii) any increase in the number of Ordinary Shares in issue in the Relevant Year in question. 

  

	 	(iv)	 If and whenever the Company shall issue Ordinary Shares to shareholders as a class by way of rights, or the
Company or any member of the Group or (at the direction or request 

  
 I-3 

 Annex I 
  

	 	
or pursuant to any arrangements with the Company or any member of the Group) any other company, person or entity shall issue or grant to shareholders as a class by way of rights, any options,
warrants or other rights to subscribe for or purchase or otherwise acquire any Ordinary Shares, or any securities which by their terms of issue carry (directly or indirectly) rights of conversion into, or exchange or subscription for, or the right
to acquire, any Ordinary Shares (or shall grant any such rights in respect of existing securities so issued), in each case at a price per ordinary share which is less than 95% of the Current Market Price per ordinary share on the Effective Date, the
Floor Price shall be adjusted by multiplying the Floor Price in force immediately prior to the Effective Date by the following fraction: 

  

					
		 	  A + B 
	 	
		 	 A + C 	 	

 where: 
  

	 	A	 is the number of Ordinary Shares in issue on the Effective Date; 

 

	 	B	 is the number of Ordinary Shares which the aggregate consideration (if any) receivable for the Ordinary Shares
issued by way of rights, or for the securities issued by way of rights, or for the options or warrants or other rights issued or granted by way of rights and for the total number of Ordinary Shares deliverable on the exercise thereof, would purchase
at such Current Market Price per ordinary share; and 

  

	 	C	 is the number of Ordinary Shares to be issued or, as the case may be, the maximum number of Ordinary Shares
which may be issued upon exercise of such options, warrants or rights calculated as at the date of issue of such options, warrants or rights or upon conversion or exchange or exercise of rights of subscription or purchase or other rights of
acquisition in respect thereof at the initial conversion, exchange, subscription, purchase or acquisition price or rate, 

provided that if on the Effective Date such number of Ordinary Shares is to be determined by reference to the application of a formula
or other variable feature or the occurrence of any event at some subsequent time, then for the purposes of this paragraph (iv), “C” shall be determined by the application of such formula or variable feature or as if the relevant event
occurs or had occurred as at the Effective Date and as if such conversion, exchange, subscription, purchase or acquisition had taken place on the Effective Date. 

Such adjustment shall become effective on the Effective Date. 

“Effective Date” means, for purposes of this paragraph (iv), the first date on which the Ordinary Shares are traded ex-rights, ex-options or ex-warrants on the Relevant Stock Exchange. 

 

	 	(v)	 If and whenever the Company or any member of the Group or (at the direction or request or pursuant to any
arrangements with the Company or any member of the Group) any other company, person or entity shall issue any securities (other than Ordinary Shares or options, warrants or other rights to subscribe for or purchase or otherwise acquire any Ordinary
Shares or securities which by their terms carry (directly or indirectly) rights of 

  
 I-4 

 Annex I 
  

	 	
conversion into, or exchange or subscription for, or rights to otherwise acquire, Ordinary Shares) to shareholders as a class by way of rights or grant to shareholders as a class by way of rights
any options, warrants or other rights to subscribe for or purchase or otherwise acquire any securities (other than Ordinary Shares or options, warrants or other rights to subscribe for or purchase or otherwise acquire Ordinary Shares or securities
which by their term carry (directly or indirectly) rights of conversion into, or exchange or subscription for, rights to otherwise acquire, Ordinary Shares), the Floor Price shall be adjusted by multiplying the Floor Price in force immediately prior
to the Effective Date by the following fraction: 

  

					
		 	  A – B 
	 	
		 	 A 	 	

 where: 
  

	 	A	 is the Current Market Price of one ordinary share on the Effective Date; and 

 

	 	B	 is the Fair Market Value on the Effective Date of the portion of the rights attributable to one ordinary share.

 Such adjustment shall become effective on the Effective Date. 

“Effective Date” means, for purposes of this paragraph (v), the first date on which the Ordinary Shares are traded ex-the relevant securities or ex-rights, ex-option or ex-warrants on the Relevant Stock
Exchange. 
  

	 	(vi)	 If and whenever the Company shall issue (otherwise than as mentioned in paragraph (iv) above) wholly for
cash or for no consideration any Ordinary Shares (other than Ordinary Shares issued on conversion of the Securities or comparable contingent convertible capital securities or on the exercise of any rights of conversion into, or exchange or
subscription for or purchase of, or right to otherwise acquire Ordinary Shares) or if and whenever the Company or any member of the Group or (at the direction or request or pursuance to any arrangements with the Company or any member of the Group)
any other company, person or entity shall issue or grant (otherwise than as mentioned in paragraph (iv) above) wholly for cash or for no consideration any options, warrants or other rights to subscribe for or purchase or otherwise acquire any
Ordinary Shares (other than, for the avoidance of doubt, the Securities or any Further Capital Securities or comparable contingent convertible capital securities), in each case at a price per ordinary share which is less than 95% of the Current
Market Price per ordinary share on the date of the first public announcement of the terms of such issue or grant, the Floor Price shall be adjusted by multiplying the Floor Price in force immediately prior to the Effective Date by the following
fraction: 

  

					
		 	  A + B 
	 	
		 	 A + C 	 	

 where: 
  

	 	A	 is the number of Ordinary Shares in issue immediately before the issue of such Ordinary Shares or the grant of
such options, warrants or rights; 

  
 I-5 

 Annex I 
  

	 	B	 is the number of Ordinary Shares which the aggregate consideration (if any) receivable for the issue of such
Ordinary Shares or, as the case may be, for the Ordinary Shares to be issued or otherwise made available upon the exercise of any such options, warrants or rights, would purchase at such Current Market Price per ordinary share; and

  

	 	C	 is the number of Ordinary Shares to be issued pursuant to such issue of such Ordinary Shares or, as the case
may be, the maximum number of Ordinary Shares which may be issued upon exercise of such options, warrants or rights calculated as at the date of issue of such options, warrants or rights, 

provided that if on the Effective Date such number of Ordinary Shares is to be determined by reference to the application of a formula
or other variable feature or the occurrence of any event at some subsequent time, then for the purposes of this paragraph (vi), “C” shall be determined by the application of such formula or variable feature or as if the relevant event
occurs or had occurred as at the Effective Date and as if such conversion, exchange, subscription, purchase or acquisition had taken place on the Effective Date. 

Such adjustment shall become effective on the Effective Date. 

“Effective Date” means, for purposes of this paragraph (vi), the date of issue of such Ordinary Shares or, as the case may be,
the grant of such options, warrants or rights. 
  

	 	(vii)	 If and whenever the Company or any member of the Group or (at the direction or request of or pursuant to any
arrangements with the Company or any member of the Group) any other company, person or entity (otherwise than as mentioned in paragraphs (iv) through (vi) above) shall issue wholly for cash or for no consideration any securities (other than,
for the avoidance of doubt, the Securities or any Further Capital Securities or comparable contingent convertible capital securities) which by their terms of issue carry (directly or indirectly) rights of conversion into, or exchange or subscription
for, purchase of, or rights to otherwise acquire, Ordinary Shares Ordinary Shares (or shall grant any such rights in respect of existing securities so issued) or securities which by their terms might be reclassified/redesignated as Ordinary Shares,
and the price per ordinary share upon conversion, exchange, subscription, purchase, acquisition or redesignation is less than 95% of the Current Market Price per ordinary share on the date of the first public announcement of the terms of issue of
such securities (or the terms of such grant), the Floor Price shall be adjusted by multiplying the Floor Price in force immediately prior to the Effective Date by the following fraction: 

 

					
		 	  A + B 
	 	
		 	 A + C 	 	

 where: 
  

	 	A	 is the number of Ordinary Shares in issue immediately before such issue or grant (but where the relevant
securities carry rights of conversion into or rights of exchange or subscription for, purchase of, or rights to otherwise acquire Ordinary Shares which have been issued, purchased or acquired by the Company or any member of the Group (or at the
direction or request or pursuant to any arrangements with the Company or any member of the Group) for the purposes of or in connection with such issue, less the number of such Ordinary Shares so issued, purchased or acquired); 

  
 I-6 

 Annex I 
  

	 	B	 is the number of Ordinary Shares which the aggregate consideration (if any) receivable for the Ordinary Shares
to be issued or otherwise made available upon conversion or exchange or upon exercise of the right of subscription, purchase or acquisition attached to such securities or, as the case may be, for the Ordinary Shares to be issued or to arise from any
such reclassification/redesignation would purchase at such Current Market Price per ordinary share; and 

  

	 	C	 is the maximum number of Ordinary Shares to be issued or otherwise made available upon conversion or exchange
of such securities or upon the exercise of such right of subscription attached thereto at the initial conversion, exchange, subscription, purchase or acquisition price or rate or, as the case may be, the maximum number of Ordinary Shares which may
be issued or arise from any such reclassification/redesignation; 

 provided that if on the Effective Date such
number of Ordinary Shares is to be determined by reference to the application of a formula or other variable feature or the occurrence of any event at some subsequent time (which may be when such securities are converted or exchanged or rights of
subscription, purchase or acquisition are exercised or, as the case may be, such securities are reclassified/redesignated or at such other time as may be provided), then for the purposes of this paragraph (vii), “C” shall be determined by
the application of such formula or variable feature or as if the relevant event occurs or had occurred as at the Effective Date and as if such conversion, exchange, subscription, purchase or acquisition or, as the case may be,
reclassification/redesignation had taken place on the Effective Date. 
 Such adjustment shall become effective on the Effective Date. 

“Effective Date” means, for purposes of this paragraph (vii), the date of issue of such Securities or, as the case may be, the
grant of such rights. 
  

	 	(viii)	 If and whenever there shall be any modification of the rights of conversion, exchange, subscription, purchase
or acquisition attaching to any securities (other than, for the avoidance of doubt, the Securities or any Further Capital Securities or comparable contingent convertible capital securities) as are mentioned in paragraph (vii) above (other than
in accordance with the terms (including terms as to adjustment) applicable to such securities upon issue) so that following such modification the consideration per ordinary share has been reduced and is less than 95% of the Current Market Price per
ordinary share on the date of the first public announcement of the proposals for such modification, the Floor Price shall be adjusted by multiplying the Floor Price in force immediately prior to the Effective Date by the following fraction:

  

					
		 	  A + B 
	 	
		 	 A + C 	 	

 where: 
  

	 	A	 is the number of Ordinary Shares in issue immediately before such modification (but where the relevant
securities carry rights of conversion into or rights of 

  
 I-7 

 Annex I 
  

	 	
exchange or subscription for, or purchase or acquisition of, Ordinary Shares which have been issued, purchased or acquired by the Company or any member of the Group (or at the direction or
request or pursuant to any arrangements with the Company or any member of the Group) for the purposes of or in connection with such securities, less the number of such Ordinary Shares so issued, purchased or acquired); 

 

	 	B	 is the number of Ordinary Shares which the aggregate consideration (if any) receivable for the Ordinary Shares
to be issued or otherwise made available upon conversion or exchange or upon exercise of the right of subscription, purchase or acquisition attached to the securities so modified would purchase at such Current Market Price per ordinary share or, if
lower, the existing conversion, exchange, subscription, purchase or acquisition price or rate of such securities; and 

  

	 	C	 is the maximum number of Ordinary Shares which may be issued or otherwise made available upon conversion or
exchange of such securities or upon the exercise of such rights of subscription, purchase or acquisition attached thereto at the modified conversion, exchange, subscription, purchase or acquisition price or rate but giving credit in such manner as
an Independent Conversion Adviser in good faith shall consider appropriate for any previous adjustment under this paragraph (viii) or paragraph (vii) above; 

provided that if on the Effective Date such number of Ordinary Shares is to be determined by reference to the application of a formula
or other variable feature or the occurrence of any event at some subsequent time (which may be when such securities are converted or exchanged or rights of subscription, purchase or acquisition are exercised or at such other time as may be provided)
then for the purposes of this paragraph (viii), “C” shall be determined by the application of such formula or variable feature or as if the relevant event occurs or had occurred as at the Effective Date and as if such conversion, exchange,
subscription, purchase or acquisition had taken place on the Effective Date. 
 Such adjustment shall become effective on the Effective Date.

 “Effective Date” means, for purposes of this paragraph (viii), the date of modification of the rights of conversion,
exchange, subscription, purchase or acquisition attaching to such securities. 
  

	 	(ix)	 If and whenever the Company or any member of the Group or (at the direction or request of or pursuant to any
arrangements with the Company or any member of the Group) any other company, person or entity shall offer any securities in connection with which shareholders as a class are entitled to participate in arrangements whereby such securities may be
acquired by them (except where the Floor Price is required to be adjusted under paragraphs (ii) through (vi) above (or would be required to be so adjusted if the relevant issue or grant was at less than 95% of the Current Market Price per
ordinary share on the relevant dealing day under paragraph (v) above)) the Floor Price shall be adjusted by multiplying the Floor Price in force immediately before the Effective Date by the following fraction: 

 

					
		 	  A – B 
	 	
		 	 A	 	

  
 I-8 

 Annex I 
  

 where: 
  

	 	A	 is the Current Market Price of one ordinary share on the Effective Date; and 

 

	 	B	 is the Fair Market Value on the Effective Date of the portion of the relevant offer attributable to one
ordinary share. 

 Such adjustment shall become effective on the Effective Date. 

“Effective Date” means, for purposes of this paragraph (ix), the first date on which the Ordinary Shares are traded ex-rights on the Relevant Stock Exchange. 
  

	 	(x)	 If the Company determines that a reduction to the Floor Price should be made for whatever reason, the Floor
Price will be reduced (either generally or for a specified period as notified to Holders of the Securities) in such manner and with effect from such date as the Company shall determine and notify to the Holders of the Securities.

 For the purpose of any calculation of the consideration receivable or price pursuant to paragraphs (iv) and (vi)
– (viii), the following provisions shall apply: 
  

	 	(i)	 the aggregate consideration receivable or price for Ordinary Shares issued for cash shall be the amount of such
cash; 

  

	 	(ii)	 (x) the aggregate consideration receivable or price for Ordinary Shares to be issued or otherwise made
available upon the conversion or exchange of any securities shall be deemed to be the consideration or price received or receivable for any such securities and (y) the aggregate consideration receivable or price for Ordinary Shares to be issued
or otherwise made available upon the exercise of rights of subscription attached to any securities or upon the exercise of any options, warrants or rights shall be deemed to be that part (which may be the whole) of the consideration or price
received or receivable for such securities or, as the case may be, for such options, warrants or rights which are attributed by the Company to such rights of subscription or, as the case may be, such options, warrants or rights or, if no part of
such consideration or price is so attributed, the Fair Market Value of such rights of subscription or, as the case may be, such options, warrants or rights as at the applicable Effective Date as described in paragraphs (iv) and (vi) –
(viii) above, as the case may be plus in the case of each of (x) and (y) above, the additional minimum consideration receivable or price (if any) upon the conversion or exchange of such securities, or upon the exercise of such
rights or subscription attached thereto or, as the case may be, upon exercise of such options, warrants or rights and (z) the consideration receivable or price per ordinary share upon the conversion or exchange of, or upon the exercise of such
rights of subscription attached to, such securities or, as the case may be, upon the exercise of such options, warrants or rights shall be the aggregate consideration or price referred to in (x) or (y) above (as the case may be) divided by
the number of Ordinary Shares to be issued upon such conversion or exchange or exercise at the initial conversion, exchange or subscription price or rate; 

  

	 	(iii)	 if the consideration or price determined pursuant to clause (i) or (ii) above (or any component thereof)
shall be expressed in a currency other than the Relevant Currency, it shall be converted into the Relevant Currency at the Prevailing Rate on the relevant Effective Date (in the case of clause (i) above) or the relevant date of first public
announcement (in the case of clause (ii) above); 

  
 I-9 

 Annex I 
  

	 	(iv)	 in determining the consideration or price pursuant to the above, no deduction shall be made for any commissions
or fees (howsoever described) or any expenses paid or incurred for any underwriting, placing or management of the issue of the relevant Ordinary Shares or securities or options, warrants or rights, or otherwise in connection therewith; and

  

	 	(v)	 the consideration or price shall be determined as provided above on the basis of the consideration or price
received, receivable, paid or payable, regardless of whether all or part thereof is received, receivable, paid or payable by or to the Company or another entity 

Notwithstanding the foregoing provisions: 
  

	 	(A)	 where the events or circumstances giving rise to any adjustment pursuant to paragraphs (i) – (x) above
have already resulted or will result in an adjustment to the Floor Price or where the events or circumstances giving rise to any adjustment arise by virtue of any other events or circumstances which have already given or will give rise to an
adjustment to the Floor Price or where more than one event which gives rise to an adjustment to the Floor Price occurs within such a short period of time that, in the opinion of the Company, a modification to the operation of the adjustment
provisions is required to give the intended result, such modification shall be made to the operation of the adjustment provisions as may be determined in good faith by an Independent Conversion Adviser to be in its opinion appropriate to give the
intended result; 

  

	 	(B)	 such modification shall be made to the operation of the Indenture as may be determined in good faith by an
Independent Conversion Adviser to be in its opinion appropriate (i) to ensure that an adjustment to the Floor Price or the economic effect thereof shall not be taken into account more than once, (ii) to ensure that the economic effect of a
Dividend is not taken into account more than once and (iii) to reflect a redenomination of the issued Ordinary Shares for the time being into a new currency; 

 

	 	(C)	 for the avoidance of doubt, the issue of Ordinary Shares following a Conversion shall not result in an
adjustment to the Floor Price; 

  

	 	(D)	 no adjustment shall be made to the Floor Price where Ordinary Shares or any other securities (including rights,
warrants and options) are issued, offered, exercised, allotted, purchased, appropriated, modified or granted to, or for the benefit of, employees or former employees (including directors holding or formerly holding executive office or the personal
service company of any such person) or their spouses or relatives, in each case, of the Company or any of its Subsidiaries or any associated company or to a trustee or trustees to be held for the benefit of any such person, in any such case pursuant
to any share or option scheme; 

 Record Date 

If the record date in respect of any consolidation, reclassification/redesignation or sub-division as
is mentioned in paragraph (i) under “— Adjustment of Floor Price” above, or the record date or other due date for the establishment of entitlement for any such issue, distribution, grant or offer (as the case may

  
 I-10 

 Annex I 
  

 
be) as is mentioned in paragraph (ii) – (v) or (ix) under “— Adjustment of Floor Price” above, or the date of the first public announcement of the terms of any such issue
or grant as is mentioned in paragraphs (vi) and (vii) under “— Adjustment of Floor Price” above or of the terms of any such modification as is mentioned in paragraph (viii) under “— Adjustment of Floor
Price” above, falls after the date on which the Conversion Notice is given in relation to the Conversion but before such Ordinary Shares are issued, then the Company shall procure the execution of the corresponding adjustment mechanism under
“— Adjustment of Floor Price” above so that the calculation of the number of Conversion Shares to be issued and delivered to the Conversion Shares Depository takes into account the Floor Price as so adjusted. 

The Company shall not issue any additional Conversion Shares if the Conversion occurs after the record date in respect of any consolidation,
reclassification or sub-division as is mentioned in paragraph (i) of “— Adjustment of Floor Price” above, or the record date or other due date for the establishment of entitlement for
any such issue, distribution, grant or offer (as the case may be) as is mentioned in paragraph (ii) – (v) or (ix) under “— Adjustment of Floor Price” above, or the date of the first public announcement of the terms of
any such issue or grant as is mentioned in paragraphs (vi) and (vii) under “— Adjustment of Floor Price” above or of the terms of any such modification as is mentioned in paragraph (viii) under
“— Adjustment of Floor Price” above, but before the relevant adjustment to the relevant price becomes effective under such section. 

Conversion Calculation Agent and Independent Conversion Adviser 

So long as any Securities are outstanding, there shall at all times be a Conversion Calculation Agent, which may be the Company or another
person appointed by the Company to serve in such capacity, who shall be responsible in consultation with the Company for the calculation of all adjustments to the Floor Price and all related determinations required to be made in connection
therewith. All such calculations and determinations performed by the Conversion Calculation Agent shall be conclusive and binding on the Holders and Beneficial Owners of the Securities or any interest therein, save in the case of bad faith or
manifest error. If any provision described herein under “Anti-Dilution Provisions” at any time calls for any calculation or determination to be made by an Independent Conversion Adviser, which may include the Conversion Calculation Agent
appointed by the Company to act in such Independent Conversion Adviser capacity, if the person then serving as Conversion Calculation Agent is not wholly independent of the Company, the Company shall use commercially reasonable efforts to appoint an
Independent Conversion Adviser which is wholly independent of the Company to make such calculation or determination. A written opinion of such Independent Conversion Adviser in respect of such calculation or determination shall be conclusive and
binding on the Company and the Holders and Beneficial Owners of the Securities or any interest therein, save in the case of manifest error. The Company has appointed Conv-Ex Advisors Limited as the initial
Conversion Calculation Agent. The Company may change the Conversion Calculation Agent at any time without prior notice to any Holder or Beneficial Owner of the Securities. 

The Conversion Calculation Agent (if not the Company) shall act solely upon request from, and solely as agent of, the Company and will not
thereby assume any obligations towards or relationship of agency or trust with, and it shall not be liable and shall incur no liability as against, the Holders of Securities. 

Rounding Down and Notice of Adjustment to the Floor Price 

On any adjustment, if the resultant Floor Price has more decimal places than the initial Floor Price, it shall be rounded down to the same
number of decimal places as the initial Floor Price. No adjustment shall be made to the Floor Price where such adjustment (rounded down if applicable) would be less than 1% of the Floor Price then in effect. Any adjustment not required to be made,
and/or any 

  
 I-11 

 Annex I 
  

 
amount by which the Floor Price has been rounded down, shall be carried forward and taken into account in any subsequent adjustment, and such subsequent adjustment shall be made on the basis that
the adjustment not required to be made had been made at the relevant time and/or, as the case may be, that the relevant rounding down had not been made. 

Notice of any adjustments to the Floor Price shall be given by the Company to Holders of the Securities via DTC (or, if the Securities are
held in definitive form, via the Trustee) promptly after the determination thereof and in accordance with Sections 1.05 and 1.06 of the Base Indenture. 

Definitions 

Unless otherwise provided, for the purposes of this Annex I: 

“Applicable Dividend” has the meaning set forth in the definition of “Extraordinary Dividend” below. 

“Cash Dividend” means (i) any Dividend which is to be paid or made in cash (in whatever currency), but other than any
Dividend falling within paragraph (b) of the definition of “Spin-Off,” and (ii) any Dividend determined to be a Cash Dividend pursuant to paragraph (i) of the definition of
“Dividend,” provided that a Dividend falling within paragraph (iii) or (iv) of the definition of “Dividend” shall be treated as being a Non-Cash Dividend. 

“Current Market Price” means, in respect of an ordinary share at a particular date, the average of the daily Volume Weighted
Average Price of an ordinary share on each of the five consecutive dealing days ending on the dealing day immediately preceding such date; provided that, if at any time during the said five-dealing-day
period the Volume Weighted Average Price shall have been based on a price ex-Dividend (or ex- any other entitlement) and during some other part of that period the Volume
Weighted Average Price shall have been based on a price cum-Dividend (or cum- any other entitlement), then: 

 

	 	(i)	 if the Ordinary Shares to be issued and delivered do not rank for the Dividend (or entitlement) in question,
the Volume Weighted Average Price on the dates on which the Ordinary Shares shall have been based on a price cum-Dividend (or cum- any other entitlement) shall, for the
purposes of this definition, be deemed to be the amount thereof reduced by an amount equal to the Fair Market Value of any such Dividend or entitlement per ordinary share as at the date of the first public announcement relating to such Dividend or
entitlement; or 

  

	 	(ii)	 if the Ordinary Shares to be issued and delivered do rank for the Dividend (or entitlement) in question, the
Volume Weighted Average Price on the dates on which the Ordinary Shares shall have been based on a price ex-Dividend (or ex- any other entitlement) shall, for the
purposes of this definition, be deemed to be the amount thereof increased by an amount equal to the Fair Market Value of such Dividend or entitlement per ordinary share as at the date of the first public announcement relating to such Dividend or
entitlement, 

 and provided further that, if on each of the said five dealing days the Volume Weighted Average
Price shall have been based on a price cum-Dividend (or cum- any other entitlement) in respect of a Dividend (or other entitlement) which has been declared or announced
but the Ordinary Shares to be issued and delivered do not rank for that Dividend (or other entitlement), the Volume Weighted Average Price on each of such dates shall, for the purposes of this definition, be deemed to be the amount thereof reduced
by an amount equal to the Fair Market Value of any 

  
 I-12 

 Annex I 
  

 
such Dividend or entitlement per ordinary share as at the date of first public announcement relating to such Dividend or entitlement, and provided further that, if the Volume Weighted
Average Price of an ordinary share is not available on one or more of the said five dealing days (disregarding for this purpose the proviso to the definition of Volume Weighted Average Price), then the average of such Volume Weighted Average Prices
which are available in that five-dealing-day period shall be used (subject to a minimum of two such prices) and if only one, or no, such Volume Weighted Average Price is available in the relevant period, the
Current Market Price shall be determined in good faith by an Independent Conversion Adviser. 
 A “dealing day” means a day
on which the Relevant Stock Exchange or relevant stock exchange or securities market is open for business and on which Ordinary Shares, securities, Spin-Off Securities, options, warrants or other rights (as
the case may be) may be dealt in (other than a day on which the Relevant Stock Exchange or relevant stock exchange or securities market is scheduled to or does close prior to its regular weekday closing time). 

“Dividend” means any dividend or distribution to holders of Ordinary Shares (including a
Spin-Off) whether of cash, assets or other property (and for these purposes a distribution of assets includes without limitation an issue of Ordinary Shares or other securities credited as fully or partly paid
up by way of capitalization of profits or reserves), and however described and whether payable out of share premium account, profits, retained earnings or any other capital or revenue reserve or account, and including a distribution or payment to
holders of Ordinary Shares upon or in connection with a reduction of capital provided that: 
  

	 	(i)	 where: 

  

	 	(A)	 a Dividend in cash is announced which may at the election of a shareholder or shareholders of the Company be
satisfied by the issue or delivery of Ordinary Shares or other property or assets, or where a capitalization of profits or reserves is announced which may at the election of a shareholder or shareholders be satisfied by the payment of cash, then the
Dividend in question shall be treated as a Cash Dividend of an amount equal to the greater of (A) the Fair Market Value of such cash amount and (B) the Current Market Price of such Ordinary Shares as at the first date on which the Ordinary
Shares are traded ex-the relevant Dividend on the Relevant Stock Exchange or, as the case may be, the record date or other due date for establishment of entitlement in respect of the relevant capitalization
or, as the case may be, the Fair Market Value of such other property or assets as at the date of the first public announcement of such Dividend or capitalization or, in any such case, if later, the date on which the number of Ordinary Shares (or
amount of such other property or assets, as the case may be) which may be issued and delivered is determined; or 

  

	 	(B)	 there shall be any issue of Ordinary Shares by way of capitalization of profits or reserves (including any
share premium account or capital redemption reserve) where such issue is or is expressed to be in lieu of a Dividend (whether or not a Cash Dividend equivalent or amount is announced), or a Dividend in cash that is to be satisfied by the issue or
delivery of Ordinary Shares or other property or assets, the capitalization or Dividend in question shall be treated as a Cash Dividend of an amount equal to the Current Market Price of such Ordinary Shares or, as the case may be, the Fair Market
Value of such other property or assets, as at the first date on which the Ordinary Shares are traded ex-the relevant capitalization or, as the case may be, ex-the
relevant Dividend on the Relevant Stock Exchange or, if later, the date on which the number of Ordinary Shares to be issued and delivered is determined; 

  
 I-13 

 Annex I 
  

	 	(ii)	 any issue of Ordinary Shares as described in paragraph (i) or (ii) under “— Adjustment of Floor
Price” above shall be disregarded; 

  

	 	(iii)	 (A) a purchase or redemption or buy back of share capital of the Company by or on behalf of the Company in
accordance with any general authority for such purchases, redemptions or buy backs approved by a general meeting of shareholders and otherwise in accordance with the limitations prescribed under Dutch law for dealings generally by a company in its
own shares and provided that the price paid for such share capital by or on behalf of the Company shall be within price limits that apply to any safe harbor for share buy-backs by the Company under applicable
insider trading and market manipulation rules (on the Issue Date being Commission Delegated Regulation (EU) 2016/1052) shall not constitute a Dividend and (B) and any other purchase or redemption or buy back of share capital of the Company by
or on behalf of the Company shall not constitute a Dividend unless, in the case of (B) above, the weighted average price per ordinary share (before expenses) on any one day (a “Specified Share Day”) in respect of such purchases
or redemptions or buy backs (translated, if not in the Relevant Currency, into the Relevant Currency at the Prevailing Rate on such day) exceeds by more than 5% the average of the daily Volume Weighted Average Price of an Ordinary Shares on the 5
dealing days immediately preceding the Specified Share Day or, where an announcement (excluding, for the avoidance of doubt for these purposes, any general authority for such purchases, redemptions or buy backs approved by a general meeting of
shareholders or any notice convening such a meeting of shareholders) has been made of the intention to purchase, redeem or buy back Ordinary Shares at some future date at a specified price or where a tender offer is made, on the 5 dealing days
immediately preceding the date of such announcement or the date of first public announcement of such tender offer (and regardless of whether or not a price per ordinary share, a minimum price per ordinary share or a price range or a formula for the
determination thereof is or is not announced at such time), as the case may be, in which case such purchase, redemption or buy back shall be deemed to constitute a Dividend in the Relevant Currency in an amount equal to the amount by which the
aggregate price paid (before expenses) in respect of such Ordinary Shares purchased, redeemed or bought back by the Company or, as the case may be, any member of the Group (translated where appropriate into the Relevant Currency as provided above)
exceeds the product of (i) 105% of the daily Volume Weighted Average Price of an ordinary share determined as aforesaid and (ii) the number of Ordinary Shares so purchased, redeemed or bought back; 

 

	 	(iv)	 if the Company or any member of the Group shall purchase, redeem or buy back any depositary or other receipts
or certificates representing Ordinary Shares, the provisions of paragraph (iii) above shall be applied in respect thereof in such manner and with such modifications (if any) as shall be determined in good faith by an Independent Conversion
Adviser; and 

  

	 	(v)	 where a dividend or distribution is paid or made to shareholders pursuant to any plan implemented by the
Company for the purpose of enabling shareholders to elect, or which may require shareholders, to receive dividends or distributions in respect of the Ordinary Shares held by them from a person other than (or in addition to) the Company, such
dividend or distribution shall for the purposes hereof be treated as a dividend or distribution made or paid to shareholders by the Company, and the foregoing provisions of this definition, and the provisions hereof, including references to the
Company paying or making a dividend, shall be construed accordingly. 

  
 I-14 

 Annex I 
  

 “EEA Regulated Market” means a market as defined by Article 4.1(21) of MiFID
II, as the same may be amended from time to time. 
 “Extraordinary Dividend” means (i) any Cash Dividend that is
expressly declared by the Company to be a capital distribution, extraordinary dividend, extraordinary distribution, special dividend, special distribution or return of value to shareholders (including any distribution made as a result of any capital
reduction), in which case the Extraordinary Dividend shall be such Cash Dividend, or (ii) any Cash Dividend (other than a Cash Dividend falling under clause (i) of this definition) (the “Applicable Dividend”) paid or made
in respect of the Relevant Year if (A) the Fair Market Value of the Applicable Dividend per ordinary share or (B) the sum of (I) the Fair Market Value of the Applicable Dividend per ordinary share and (II) an amount equal to the
aggregate of the Fair Market Value or Fair Market Values of any other Cash Dividend or Cash Dividends (other than a Cash Dividend or Cash Dividends falling under clause (i) of this definition) per ordinary share paid or made in respect of the
Relevant Year, exceeds the Reference Amount, and in that case the Extraordinary Dividend shall be such Applicable Dividend, provided that any Cash Dividend (other than a Cash Dividend falling under part (i) of this definition) which is not
expressed to be in respect of a given financial year of the Company, shall be deemed to be a Cash Dividend in respect of the financial year in which it is made or paid. 

“Fair Market Value” means, with respect to any property on any date, (a) in the case of a Cash Dividend, the amount of
such Cash Dividend; (b) in the case of any other cash amount, the amount of such cash; (c) in the case of securities (including Ordinary Shares), Spin-Off Securities, options, warrants or other
rights or assets publicly traded on a stock exchange or securities market of adequate liquidity (as determined by the Conversion Calculation Agent in good faith), (i) in the case of Ordinary Shares or
Spin-Off Securities, the arithmetic mean of the daily Volume Weighted Average Prices of such Ordinary Shares or Spin-Off Securities and (ii) in the case of
securities (other than Ordinary Shares or Spin-Off Securities), options, warrants or other rights or assets of the kind referred to above, the arithmetic mean of the daily closing prices of such securities,
options, warrants or other rights or assets, in the case of both (i) and (ii) above, during the period of five (5) dealing days on the principal stock exchange or securities market on which such securities, Spin-Off Securities, options, warrants or other rights or assets are then listed, admitted to trading or quoted or dealt in, commencing on such date (or, if later, the first such dealing day such securities, Spin-Off Securities, options, warrants or other rights or assets are publicly traded, quoted or dealt in on such stock exchange or securities market) or such shorter period as such securities, Spin-Off Securities, options, warrants or other rights or assets are publicly traded, quoted or dealt in on such stock exchange or securities market; and (d) in the case of securities (including Ordinary
Shares), Spin-Off Securities, options, warrants or other rights or assets not publicly traded on a stock exchange or securities market of adequate liquidity (as aforesaid), the fair market value of such
securities, Spin-Off Securities, options, warrants or other rights or assets as determined by an Independent Conversion Adviser in good faith, on the basis of a commonly accepted market valuation method and
taking account of such factors as it considers appropriate, including the market price per ordinary share, the dividend yield of an ordinary share, the volatility of such market price, prevailing interest rates and the terms of such securities, Spin-Off Securities, options, warrants or other rights or assets, including as to the expiry date and exercise price (if any) thereof. Such amounts shall, in the case of (a) above, be translated into the
Relevant Currency (if such Cash Dividend is declared or paid or payable in a currency other than the Relevant Currency) at the rate of exchange used to determine the amount payable to shareholders who were paid or are to be paid or are entitled to
be paid the Cash Dividend in the Relevant Currency and, in any other case, shall be translated into the Relevant Currency (if expressed in a currency other than the Relevant Currency) at the Prevailing Rate on that date. In addition, in the case of
(a) and (b) above, the Fair Market Value shall be determined on a gross basis, disregarding any withholding or deduction required to be made for or on account of tax, and disregarding any associated tax credit. 

  
 I-15 

 Annex I 
  

 “Further Capital Securities” means any securities issued after the Issue
Date which are contingently convertible into Ordinary Shares pursuant to their terms in the event that the Group CET1 Ratio is less than a specified percentage. 

“Independent Conversion Adviser” means an independent financial institution of international repute or independent financial
adviser with appropriate expertise (which may include the initial Conversion Calculation Agent) appointed by the Company at its own expense. 

“Non-Cash Dividend” means any Dividend which is not a Cash Dividend, and shall
include a Spin-Off. 
 A “person” includes any individual, company, corporation,
firm, partnership, joint venture, undertaking, association, organization, trust, state or agency of a state (in each case whether or not being a separate legal entity) or other legal entity. 

“Prevailing Rate” means, in respect of any pair of currencies on any calendar day, the spot rate of exchange between the
relevant currencies prevailing at or about 12:00 pm, London time, on that date as appearing on or derived from the Relevant Page or, if such a rate cannot be determined at such time, the rate prevailing at or about 12:00 pm, London time, on the
immediately preceding day on which such rate can be so determined or, if such rate cannot be so determined by reference to the Relevant Page, the rate determined in such other manner as an Independent Conversion Adviser shall in good faith
prescribe. 
 “Reference Amount” means, either: 
  

	 	(a)	 where (i) the Applicable Dividend in respect of such Relevant Year is declared after the date on which the
Group’s audited consolidated financial statements in respect of the Relevant Year are available (the “Results Availability Date”) and (ii) no other Cash Dividends have been declared in respect of such Relevant Year prior
to the Results Availability Date: 100% of the Group’s net result from continuing and discontinued operations (before minority interests) per ordinary share in respect of such Relevant Year; or, 

 

	 	(b)	 in any other case: the greater of (i) 100% of the Group’s net results from continuing and discontinued
operations (before minority interests) per ordinary share in respect of the Relevant Year and (ii) 100% of the Group’s net results from continuing and discontinued operations (before minority interests) per ordinary share in respect of the most
recently completed financial year for which the Group’s audited consolidated financial statements are available on the date on which the first Cash Dividend in respect of the Relevant Year is declared (and such determination shall be made
promptly after the Results Availability Date), except where a Conversion Notice is delivered before such Results Availability Date, in which case the Reference Amount shall be equal to the amount determined pursuant to part (ii) of this
paragraph, and in any such case, the Floor Price for the purpose of such Conversion Notice shall be determined on the basis of an Extraordinary Dividend (if any) determined on the basis of a Reference Amount determined accordingly.

 “Regulated Market” means an EEA Regulated Market or another regulated, regularly operating, recognized
stock exchange or securities market in an OECD member state. 

  
 I-16 

 Annex I 
  

 “Relevant Currency” means euro or such other currency in which the Ordinary
Shares are quoted or dealt in on the Relevant Stock Exchange at the relevant time or for the purposes of the relevant calculation or determination. 

“Relevant Page” means the relevant page on Bloomberg or such other information service provider that displays the relevant
information, as determined by the Conversion Calculation Agent. 
 “Relevant Year” means, in respect of any Cash Dividend,
the financial year of the Company in respect of which such Cash Dividend is being paid or made, or deemed to be paid or made, as the case may be. 

“Shareholders” means the holders of Ordinary Shares. 

“Spin-Off” means (a) a distribution of
Spin-Off Securities by the Company to shareholders as a class; or (b) any issue, transfer or delivery of any property or assets (including cash or shares or other securities of or in or issued or allotted
by any entity) by any entity (other than the Company) to shareholders as a class, pursuant to any arrangements with the Company or any member of the Group. 

“Spin-Off Securities” means equity share capital of an entity other than the Company
or options, warrants or other rights to subscribe for or purchase equity share capital of an entity other than the Company. 

“Subsidiary” means each subsidiary as defined in Section 2:24a of the Dutch Civil Code for the time being of the
Company. 
 “Volume Weighted Average Price” means, in respect of an ordinary share or security or Spin-Off Security on any dealing day, the order book volume-weighted average price of an ordinary share (or security or Spin-Off Security, as applicable), published by or
derived (in the case of an ordinary share) from the relevant Bloomberg page INGA NA <Equity> HP (setting “Weighted Average Line” or any successor setting) or (in the case of a security (other than Ordinary Shares) or Spin-Off Security) from the equivalent Bloomberg page for such security or Spin-Off Security in respect of the principal stock exchange or securities market on which such
securities or Spin-Off Securities are then listed or quoted or dealt in, if any, or such other source as shall be determined in good faith to be appropriate by an Independent Conversion Adviser on such dealing
day; provided that if on any such dealing day such price is not available or cannot otherwise be determined as provided above, the Volume Weighted Average Price of an ordinary share, security or
Spin-Off Security, as the case may be, in respect of such dealing day shall be the Volume Weighted Average Price, determined as provided above, on the immediately preceding dealing day on which the same can be
so determined or determined as an Independent Conversion Adviser might otherwise determine in good faith to be appropriate. 
 References to
any act or statute or any provision of any act or statute shall be deemed also to refer to any statutory modification or re-enactment thereof or any statutory instrument, order or regulation made thereunder or
under such modification or re-enactment. 
 In making any calculation or determination of Current
Market Price or Volume Weighted Average Price, such adjustments (if any) shall be made as an Independent Conversion Adviser determines in good faith to be appropriate to reflect any consolidation or
sub-division of the Ordinary Shares or any issue of Ordinary Shares by way of capitalization of profits or reserves, or any like or similar event. 

References to any issue or offer or grant to shareholders “as a class” or “by way of rights” shall be taken to be
references to an issue or offer or grant to all or substantially all shareholders, as the case 

  
 I-17 

 Annex I 
  

 
may be, other than shareholders, as the case may be, to whom, by reason of the laws of any territory or requirements of any recognized regulatory body or any other stock exchange or securities
market in any territory or in connection with fractional entitlements, it is determined not to make such issue or offer or grant. 

  
 I-18 

 Exhibit A-1 

Form of Security 
 [THIS SECURITY
IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE HEREINAFTER REFERRED TO AND IS REGISTERED IN THE NAME OF A DEPOSITARY OR A NOMINEE THEREOF. THIS SECURITY MAY NOT BE EXCHANGED IN WHOLE OR IN PART FOR A SECURITY REGISTERED, AND NO TRANSFER OF
THIS SECURITY IN WHOLE OR IN PART MAY BE REGISTERED, IN THE NAME OF ANY PERSON OTHER THAN SUCH DEPOSITARY OR A NOMINEE THEREOF, EXCEPT IN THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE. 

BY PURCHASING THIS SECURITY, IN THE ABSENCE OF A CHANGE IN LAW OR AN ADMINISTRATIVE OR JUDICIAL RULING TO THE CONTRARY, THE HOLDER AGREES TO CHARACTERIZE THIS
SECURITY FOR ALL U.S. FEDERAL INCOME TAX PURPOSES AS PROVIDED ON THE FACE OF THIS SECURITY.] 
 ING GROEP N.V. 

3.875% Perpetual Additional Tier 1 Contingent Convertible Capital Securities 

No.
[    ]                                     
                                         
                                         
                                         
                    $[●] 
 CUSIP NO.
456837AY9 
 ISIN US456837AY94 

ING GROEP N.V., a holding company duly organized and existing under the laws of The Netherlands (herein called the “Company”,
which term includes any successor Person under the Indenture hereinafter referred to), for value received, hereby promises to pay to                 , or registered
assigns, the principal sum of $                 (                 Dollars), if and to the
extent due, and to pay interest thereon, if any, in accordance with the terms hereof and the Indenture. This Security shall have no fixed maturity or fixed redemption date. From and including the Issue Date to but excluding November 16, 2027, the
interest rate on this Security shall be 3.875% per annum. From and including November 16, 2027 and each fifth anniversary date thereafter, commencing November 16, 2027 (each such date, a “2027 Securities Reset Date”) to
(but excluding) the next following Reset Date, the applicable per annum rate shall be equal to the sum of the applicable U.S. Treasury Rate on the Reset Determination Date and 2.862%. Subject to the provisions on the reverse of this Security
relating to cancellation and deemed cancellation of interest and to Sections 2.03 and 2.04 of the Fourth Supplemental Indenture, interest, if any, shall be payable semiannually in arrears on May 16 and November 16 of each year (each, an
“Interest Payment Date”), commencing on November 16, 2021, and shall be calculated on the basis of a year of 360 days consisting of twelve (12) months of thirty (30) days each and, in the case of an incomplete month,
the actual number of days elapsed. 
 The interest, if any, so payable, and paid or duly provided for, on any Interest Payment Date will, as
provided in the Indenture, be paid to the Person in whose name this Security (or one or more Predecessor Securities) is registered at the close of business on the Regular Record Date for such interest which shall be the Business Day immediately
preceding each Interest Payment Date (whether or not a Business Day). 
 Payment of the principal of and interest on this Security will be
made at the office or agency of the Company maintained for that purpose in The City of New York in such coin or currency of the United States of America as at the time of payment is legal tender for payment of public and private debts; provided,
however, that at the option of the Company payment of interest may be made by check mailed to the address of the Person entitled thereto as such address shall appear in the Security Register. If any payment of principal of or interest on this
Security is scheduled to be made on a day that is not a Business Day, payment may be made on the following day without adjustment. 

  
 A-1-1 

 Exhibit A-1 
  

 This Security shall be governed by and construed in accordance with the laws of the State of
New York, except for the subordination and waiver of set-off provisions referred to herein and in Sections 7.01 and 7.02 of the Fourth Supplemental Indenture, which are governed by, and construed in accordance
with, Dutch law. 
 Reference is hereby made to the further provisions of this Security set forth on the reverse hereof, which further
provisions shall for all purposes have the same effect as if set forth at this place. 
 THIS SECURITY IS NOT A DEPOSIT AND IS NOT INSURED
BY THE UNITED STATES FEDERAL DEPOSIT INSURANCE CORPORATION OR ANY OTHER GOVERNMENT AGENCY OF THE UNITED STATES OR THE NETHERLANDS. 
 Unless
the certificate of authentication hereon has been executed by the Trustee referred to on the reverse hereof, directly or through an Authenticating Agent, by manual signature of an authorized signatory, this Security shall not be entitled to any
benefit under the Indenture or be valid or obligatory for any purpose. 

  
 A-1-2 

 IN WITNESS WHEREOF, the Company has caused this instrument to be duly executed. 

 

							
	Date:	 		 	ING GROEP N.V.
				
		 		 	By:	 	 
		 		 		 	Name:
		 		 		 	Title:
				
		 		 	By:	 	 
		 		 		 	Name:
		 		 		 	Title:

 Trustee’s Certificate of Authentication 

This is one of the Securities of the series designated herein referred to in the Indenture. 

 

							
	Date:	 		 	 THE BANK OF NEW YORK MELLON, LONDON BRANCH

As Trustee

				
		 		 	By:	 	 
		 		 		 	Authorized Signatory

 Exhibit A-1 

(Reverse of Security) 
 This
Security is one of a duly authorized issue of securities of the Company (herein called the “Securities” and each, a “Security”) issued and to be issued in one or more series under and governed by the Capital
Securities Indenture, dated as of April 16, 2015 (herein called the “Base Indenture”), between the Company and The Bank of New York Mellon, London Branch, as Trustee (herein called the “Trustee,” which term
includes any successor trustee under the Base Indenture), as supplemented and amended by the Fourth Supplemental Indenture, dated as of September 14, 2021 (the “Fourth Supplemental Indenture” and, together with the Base Indenture,
the “Indenture”), and reference is hereby made to the Indenture, the terms of which are incorporated herein by reference, for a statement of the respective rights, limitations of rights, duties and immunities thereunder of the
Company, the Trustee, the holders of Senior Instruments and the Holders of the Securities and of the terms upon which the Securities are, and are to be, authenticated and delivered. Insofar as the provisions of the Indenture may conflict with the
provisions set forth in this Security, the former shall control for purposes of this Security. 
 This Security is one of the series
designated on the face hereof, limited to a principal amount of $1,000,000,000, which amount may be increased at the option of the Company without the consent of the Holders of the Securities of this Series. References herein to “this
series” mean the series designated on the face hereof. 
 This Security may be redeemed in certain circumstances at the option of
the Company as set forth in the Indenture. 
 This Security may be automatically converted into Ordinary Shares or other securities of the
Company as set forth in the Indenture. 
 Subject to applicable law, no Holder of this Security may exercise, claim or plead any right of set-off, compensation or retention in respect of any amount owed to it by the Company arising under, or in connection with, the Securities and each Holder of Securities shall, by virtue of its holding of any
Securities, be deemed to have waived all such rights of set-off, compensation or retention. 
 The
Indenture permits, with certain exceptions as therein provided, the amendment thereof and the modification of the rights and obligations of the Company and the rights of the Holders of the Securities of each series to be affected under the Indenture
at any time by the Company and the Trustee with the consent of the Holders of a majority in principal amount of the Securities then Outstanding of each series to be affected. The Indenture also contains provisions permitting the Holders of a
majority in aggregate principal amount of the Securities of each series then Outstanding, on behalf of the Holders of all Securities of such series, to waive compliance by the Company with certain provisions of the Indenture and certain past
Defaults under the Indenture and their consequences. Any such consent or waiver by the Holder of this Security shall be conclusive and binding upon such Holder and upon all future Holders of this Security and of any Security issued upon the
registration of transfer hereof or in exchange herefor or in lieu hereof, whether or not notation of such consent or waiver is made upon this Security. 

As provided in and subject to the provisions of the Indenture, the Holder of this Security shall not have any right to institute any
proceeding, judicial or otherwise, with respect to the Indenture or for the appointment of a receiver or trustee or for any other remedy thereunder, unless such Holder shall have previously given the Trustee written notice of a continuing Event of
Default with respect to the Securities of this series, the Holders of not less than 25% in aggregate principal amount of the Securities of this series then Outstanding shall have made written request to the Trustee to institute proceedings in
respect of such Event of Default as Trustee and offered to the Trustee security or indemnity satisfactory to the 

  
 A-1-4 

 Exhibit A-1 
  

 
Trustee in its sole discretion against the costs, expenses and liabilities to be incurred in compliance with such request, the Trustee shall not have received from the Holders of a majority in
principal amount of Securities of this series then Outstanding a direction inconsistent with such request, and shall have failed to institute any such proceeding, for sixty (60) days after receipt of such notice, request and offer of indemnity.

 Notwithstanding any contrary provisions in this Security, nothing shall impair the right of a Holder of this Security under the Trust
Indenture Act, absent such Holder’s consent, to sue for any payments due but unpaid with respect to this Security. 
 As provided in
the Indenture and subject to certain limitations therein set forth, the transfer of this Security is registrable in the Security Register, upon surrender of this Security for registration of transfer at the office or agency of the Company in any
place where the principal of this Security is payable, duly endorsed by, or accompanied by a written instrument of transfer in form satisfactory to the Company and the Security Registrar duly executed by, the Holder hereof or his attorney duly
authorized in writing. Thereupon one or more new Securities of this series and of like tenor, of authorized denominations and for the same aggregate principal amount, will be issued to the designated transferee or transferees. 

The Securities of this series are issuable only in registered form without coupons in denominations of $200,000 and integral multiples of
$1,000 in excess thereof. As provided in the Indenture and subject to certain limitations therein set forth, Securities are exchangeable for a like aggregate principal amount of Securities of a different authorized denomination, as requested by the
Holder surrendering the same. 
 No service charge shall be made for any such registration of transfer or exchange, but the Company may
require payment of a sum sufficient to cover any tax or other governmental charge payable in connection therewith. 
 Prior to due
presentment of this Security for registration of transfer, the Company, the Trustee and any agent of the Company or the Trustee may treat the Person in whose name this Security is registered as the owner hereof for all purposes, whether or not this
Security be overdue, and neither the Company, the Trustee nor any such agent shall be affected by notice to the contrary. 
 All terms used
in this Security which are defined in the Indenture shall have the meanings assigned to them in the Indenture. 
 Dutch Bail-in Power. 
  

	 	(i)	 Notwithstanding any other agreements, arrangements or understandings between the Company and any holder or
beneficial owner of the Securities, by acquiring the Securities, the Holder and each Beneficial Owner of this Security, or any interest therein, acknowledges, accepts, recognizes, agrees to be bound by, and consents to the exercise of, any Dutch Bail-in Power by the Relevant Resolution Authority that may result in the reduction (including to zero), cancellation or write-down (whether on a permanent basis or subject to
write-up by the resolution authority) of all, or a portion, of the principal amount of, or interest on, the Securities and/or the conversion of all, or a portion of, the principal amount of, or interest on,
the Securities into shares or claims which may give right to shares or other instruments of ownership or other securities or other obligations of the Company or obligations of another person (whether or not at the point of non-viability and independently of or in combination with a resolution action), including by means of a variation to the terms of the Securities (which may include amending the interest amount or the maturity or
interest payment dates, including by suspending payment for a 

  
 A-1-5 

 Exhibit A-1 
  

	 	
temporary period), or that the Securities must otherwise be applied to absorb losses, or any expropriation of the Securities, in each case, to give effect to the exercise by the Relevant
Resolution Authority of such Dutch Bail-in Power (whether at the point of non-viability or as taken together with a resolution action). The Holder and each Beneficial
Owner of this Security or any interest therein further acknowledges and agrees that the rights of Holders and Beneficial Owners of the Securities or any interest therein are subject to, and will be varied, if necessary, so as to give effect to, the
exercise of any Dutch Bail-in Power by the Relevant Resolution Authority. For the avoidance of doubt, the potential conversion of the Securities into shares, other securities or other obligations in connection
with the exercise of any Dutch Bail-in Power by the Relevant Resolution Authority is separate and distinct from a Conversion following a Trigger Event. In addition, by acquiring any Securities, the Holder and
each Beneficial Owner of this Security or any interest therein further acknowledges, agrees to be bound by, and consents to the exercise by the Relevant Resolution Authority of, any power to vary the terms of the Securities, which may include
amending the Interest Payment Dates or amount, or to suspend any payment in respect of the Securities for a temporary period. 

  

	 	(ii)	 By its acquisition of the Securities, such Holder and Beneficial Owner: 

 

	 	(a)	 acknowledges and agrees that no exercise of the Dutch Bail-in Power by
the Relevant Resolution Authority with respect to the Securities or cancellation or deemed cancellation of interest on the Securities pursuant to Sections 2.03 and 2.04 of the Fourth Supplemental Indenture shall give rise to a default for purposes
of Section 315(b) (Notice of Default) and Section 315(c) (Duties of the Trustee in Case of Default) of the Trust Indenture Act; 

  

	 	(b)	 to the extent permitted by the Trust Indenture Act, waives any and all claims against the Trustee for, agrees
not to initiate a suit against the Trustee in respect of, and agrees that the Trustee shall not be liable for, any action that the Trustee takes, or abstains from taking, in either case in accordance with the exercise of the Dutch Bail-in Power by the Relevant Resolution Authority with respect to the Securities; 

  

	 	(c)	 acknowledges and agrees that, upon the exercise of any Dutch Bail-in
Power by the Relevant Resolution Authority, (i) the Trustee shall not be required to take any further directions from Holders or Beneficial Owners of the Securities under Section 5.12 of the Base Indenture and (ii) the Indenture shall
impose no duties upon the Trustee whatsoever with respect to the exercise of any Dutch Bail-in Power by the Relevant Resolution Authority. If Holders or Beneficial Owners of the Securities have given a
direction to the Trustee pursuant to Section 5.12 of the Base Indenture prior to the exercise of any Dutch Bail-in Power by the Relevant Resolution Authority, such direction shall cease to be of further
effect upon such exercise of any Dutch Bail-in Power and shall become null and void at such time. Notwithstanding the foregoing, if, following the completion of the exercise of the Dutch Bail-in Power by the Relevant Resolution Authority, the Securities remain outstanding, then the Trustee’s duties under the Indenture shall remain applicable with respect to the Securities following such
completion to the extent that the Company and the Trustee shall agree pursuant to a supplemental indenture or an amendment to this Fourth Supplemental Indenture; and 

 

	 	(d)	 (i) consents to the exercise of any Dutch Bail-in Power as it may be
imposed without any prior notice by the Relevant Resolution Authority of its decision to exercise such power with respect to the Securities and (ii) authorizes, directs and requests DTC and

  
 A-1-6 

 Exhibit A-1 
  

	 	
any direct participant in DTC or other intermediary through which it holds such Securities to take any and all necessary action, if required, to implement (x) the Conversion and (y) the
exercise of any Dutch Bail-in Power with respect to the Securities as it may be imposed, without any further action or direction on the part of such Holder and such Beneficial Owner. 

 

	 	(iii)	 By its acquisition of the Securities, such Holder and Beneficial Owner: 

 

	 	a)	 consents to the Conversion of its Securities following a Trigger Event and consents to the appointment of the
Conversion Shares Depository and the issuance of the Conversion Shares to the Conversion Shares Depository, all of which may occur without any further action on the part of such Holder or Beneficial Owner or the Trustee. To the extent the Securities
are held in the form of global securities, such Holder or Beneficial Owner authorizes, directs and requests DTC, any direct participant therein and any other intermediary through which it holds such Securities to take any and all necessary action,
if required, to implement the Conversion without any further action or direction on the part of such Holder or Beneficial Owner or the Trustee. 

  

	 	b)	 acknowledges and agrees that (a) interest is payable solely at the discretion of the Company, and no
amount of interest shall become due and payable in respect of the relevant Interest Payment Date or related Interest Period or redemption date to the extent that it has been cancelled or deemed cancelled (in whole or in part) by the Company in its
sole discretion and/or as a result of (i) the Company having insufficient Distributable Items, (ii) the relevant interest payment’s causing the Maximum Distributable Amount to be exceeded, or (iii) a Trigger Event or a
Liquidation Event having occurred; and (b) a cancellation or deemed cancellation of interest (in each case, in whole or in part) in accordance with the terms of this Fourth Supplemental Indenture shall not constitute a default in payment or
otherwise under the terms of the Securities. 

  

	 	c)	 unconditionally and irrevocably agrees to each and every provision of this Fourth Supplemental Indenture and
the Securities and waives, to the fullest extent permitted by the Trust Indenture Act and any other applicable law, any and all claims against the Trustee arising out of its acceptance of its trusteeship for the Securities, including, without
limitation, claims related to or arising out of or in connection with a Trigger Event and/or any Conversion. 

  

	 	d)	 acknowledges and agrees that all authority conferred or agreed to be conferred by any Holder or Beneficial
Owner pursuant to the provisions described above shall be binding upon the successors, assigns, heirs, executors, administrators, trustees in bankruptcy and legal representatives of each Holder or Beneficial Owner of a Security or any interest
therein. 

  

	 	(iv)	 No repayment of the principal amount of the Securities or payment of interest on the Securities shall be come
due and payable after the exercise of any Dutch Bail-in Power by the Relevant Resolution Authority unless such repayment or payment would be permitted to be made by the Company under the laws and regulations
of The Netherlands and the European Union applicable to the Company. 

  
 A-1-7 

 Exhibit A-1 
  

	 	(v)	 Upon the exercise of the Dutch Bail-in Power by the Relevant Resolution Authority with respect to this
Security, the Company shall provide a written notice of such event to DTC for the purposes of notifying the Holder of this Security or any interest therein of such occurrence, including the amount of any cancellation of all, or a portion, of the
principal amount of, or interest on, this Security, with a copy to the Trustee for information purposes, as soon as practicable regarding such exercise of the Dutch Bail-in Power. Failure to provide such notices will not have any impact on the
effectiveness of, or otherwise invalidate, any such exercise of the Dutch Bail-in Power. 

  

	 	(vi)	 Subsequent Investors’ Agreement. Holders or Beneficial Owners of Securities that acquire them in
the secondary market shall be deemed to acknowledge, agree to be bound by and consent to the same provisions specified herein to the same extent as the Holders or Beneficial Owners of the Securities that acquire the Securities upon their initial
issuance, including, without limitation, with respect to the acknowledgement and agreement to be bound by and consent to the terms of the Securities, including in relation to interest cancellation, the Conversion, the Dutch Bail-in Power and the limitations on remedies specified in the Indenture. 

  

	 	(vii)	 Conversion Upon a Trigger Event. Such Holder or Beneficial Owner consents to the Conversion of this
Security following a Trigger Event, the appointment of the Conversion Shares Depository, and the issuance of the Conversion Shares to the Conversion Shares Depository, all of which may occur without any further action on the part of such Holder or
Beneficial Owner or the Trustee, and following which no Holder or Beneficial Owner of this Security will have any rights against the Company with respect to the payment of principal of, or interest on, such Securities. To the extent this Security is
held in the form of a Global Security, such Holder or Beneficial Owner, directs and requests the Depositary, any direct participant therein and any other intermediary through which it holds such Securities to take any and all necessary action, if
required, to implement the Conversion without any further action or direction on the part of such Holder or Beneficial Owner or the Trustee. Upon a Trigger Event and Conversion, the principal amount of the Securities may be applied in such manner as
the Company deems necessary in connection with the issue and paying up of the relevant Conversion Shares and the delivery thereof to the Conversion Shares Depository or pursuant to any Alternative Delivery Arrangements. 

 

	 	(viii)	 Interest Cancellation. Interest shall be payable on this Security solely at the discretion of the
Company, and no amount of interest shall become due and payable in respect of the relevant Interest Payment Date or related Interest Period or Redemption Date to the extent that it has been cancelled or deemed cancelled (in whole or in part) by the
Company in its sole discretion and/or as a result of (i) the Company having insufficient Distributable Items, (ii) the relevant interest payment’s causing the Maximum Distributable Amount to be exceeded, or (iii) a Trigger Event
or Liquidation Event having occurred. A cancellation or deemed cancellation of interest (in each case, in whole or in part) in accordance with the terms of the Indenture shall not constitute a default in payment or otherwise under the terms of this
Security. 

  

	 	(ix)	 Waiver of Claims. Such Holder or Beneficial Owner unconditionally and irrevocably agrees to each and
every provision of the Indenture and this Security waives, to the fullest extent permitted by the Trust Indenture Act and any other applicable law, any and all claims against the Trustee arising out of its acceptance of its trusteeship for the
Securities, including, without limitation, claims related to or arising out of or in connection with a Trigger Event and/or any Conversion. 

  

	 	(x)	 Successors and Assigns. All authority conferred or agreed to be conferred by the Holder or Beneficial
Owner of this Security shall be binding upon the successors, assigns, heirs, executors, administrators, trustees in bankruptcy and legal representatives of such Holder or Beneficial Owner. 

  
 A-1-8 

 Exhibit A-2 
  

 Form of Security 

[THIS SECURITY IS A GLOBAL SECURITY WITHIN THE MEANING OF THE INDENTURE HEREINAFTER REFERRED TO AND IS REGISTERED IN THE NAME OF A DEPOSITARY OR A NOMINEE
THEREOF. THIS SECURITY MAY NOT BE EXCHANGED IN WHOLE OR IN PART FOR A SECURITY REGISTERED, AND NO TRANSFER OF THIS SECURITY IN WHOLE OR IN PART MAY BE REGISTERED, IN THE NAME OF ANY PERSON OTHER THAN SUCH DEPOSITARY OR A NOMINEE THEREOF, EXCEPT IN
THE LIMITED CIRCUMSTANCES DESCRIBED IN THE INDENTURE. 
 BY PURCHASING THIS SECURITY, IN THE ABSENCE OF A CHANGE IN LAW OR AN ADMINISTRATIVE OR JUDICIAL
RULING TO THE CONTRARY, THE HOLDER AGREES TO CHARACTERIZE THIS SECURITY FOR ALL U.S. FEDERAL INCOME TAX PURPOSES AS PROVIDED ON THE FACE OF THIS SECURITY.] 

ING GROEP N.V. 
 4.250% Perpetual
Additional Tier 1 Contingent Convertible Capital Securities 
 No.
[    ]                                     
                                         
                                         
                                         
                    $[●] 
 CUSIP NO.
456837AY9 
 ISIN US456837AY94 

ING GROEP N.V., a holding company duly organized and existing under the laws of The Netherlands (herein called the “Company”,
which term includes any successor Person under the Indenture hereinafter referred to), for value received, hereby promises to pay to                 , or registered
assigns, the principal sum of $                 (                 Dollars), if and to the
extent due, and to pay interest thereon, if any, in accordance with the terms hereof and the Indenture. This Security shall have no fixed maturity or fixed redemption date. From and including the Issue Date to but excluding November 16, 2031, the
interest rate on this Security shall be 4.250% per annum. From and including November 16, 2031 and each fifth anniversary date thereafter, commencing November 16, 2031 (each such date, a “2031 Securities Reset Date”) to
(but excluding) the next following Reset Date, the applicable per annum rate shall be equal to the sum of the applicable U.S. Treasury Rate on the Reset Determination Date and 2.862%. Subject to the provisions on the reverse of this Security
relating to cancellation and deemed cancellation of interest and to Sections 2.03 and 2.04 of the Fourth Supplemental Indenture, interest, if any, shall be payable semiannually in arrears on May 16 and November 16 of each year (each, an
“Interest Payment Date”), commencing on November 16, 2021, and shall be calculated on the basis of a year of 360 days consisting of twelve (12) months of thirty (30) days each and, in the case of an incomplete month,
the actual number of days elapsed. 
 The interest, if any, so payable, and paid or duly provided for, on any Interest Payment Date will, as
provided in the Indenture, be paid to the Person in whose name this Security (or one or more Predecessor Securities) is registered at the close of business on the Regular Record Date for such interest which shall be the Business Day immediately
preceding each Interest Payment Date (whether or not a Business Day). 
 Payment of the principal of and interest on this Security will be
made at the office or agency of the Company maintained for that purpose in The City of New York in such coin or currency of the United States of America as at the time of payment is legal tender for payment of public and private debts; provided,
however, that at the option of the Company payment of interest may be made by check mailed to the address of the Person entitled thereto as such address shall appear in the Security Register. If any payment of principal of or interest on this
Security is scheduled to be made on a day that is not a Business Day, payment may be made on the following day without adjustment. 

  
 A-2-1 

 Exhibit A-2 
  

 This Security shall be governed by and construed in accordance with the laws of the State of
New York, except for the subordination and waiver of set-off provisions referred to herein and in Sections 7.01 and 7.02 of the Fourth Supplemental Indenture, which are governed by, and construed in accordance
with, Dutch law. 
 Reference is hereby made to the further provisions of this Security set forth on the reverse hereof, which further
provisions shall for all purposes have the same effect as if set forth at this place. 
 THIS SECURITY IS NOT A DEPOSIT AND IS NOT INSURED
BY THE UNITED STATES FEDERAL DEPOSIT INSURANCE CORPORATION OR ANY OTHER GOVERNMENT AGENCY OF THE UNITED STATES OR THE NETHERLANDS. 
 Unless
the certificate of authentication hereon has been executed by the Trustee referred to on the reverse hereof, directly or through an Authenticating Agent, by manual signature of an authorized signatory, this Security shall not be entitled to any
benefit under the Indenture or be valid or obligatory for any purpose. 

  
 A-2-2 

 IN WITNESS WHEREOF, the Company has caused this instrument to be duly executed. 

 

							
	Date:	 		 	ING GROEP N.V.
				
		 		 	By:	 	 
		 		 		 	Name:
		 		 		 	Title:
				
		 		 	By:	 	 
		 		 		 	Name:
		 		 		 	Title:

 Trustee’s Certificate of Authentication 

This is one of the Securities of the series designated herein referred to in the Indenture. 

 

							
	Date:	 		 	 THE BANK OF NEW YORK MELLON, LONDON BRANCH

As Trustee

				
		 		 	By:	 	 
		 		 		 	Authorized Signatory

 Exhibit A-2 

(Reverse of Security) 
 This
Security is one of a duly authorized issue of securities of the Company (herein called the “Securities” and each, a “Security”) issued and to be issued in one or more series under and governed by the Capital
Securities Indenture, dated as of April 16, 2015 (herein called the “Base Indenture”), between the Company and The Bank of New York Mellon, London Branch, as Trustee (herein called the “Trustee,” which term
includes any successor trustee under the Base Indenture), as supplemented and amended by the Fourth Supplemental Indenture, dated as of September 14, 2021 (the “Fourth Supplemental Indenture” and, together with the Base Indenture,
the “Indenture”), and reference is hereby made to the Indenture, the terms of which are incorporated herein by reference, for a statement of the respective rights, limitations of rights, duties and immunities thereunder of the
Company, the Trustee, the holders of Senior Instruments and the Holders of the Securities and of the terms upon which the Securities are, and are to be, authenticated and delivered. Insofar as the provisions of the Indenture may conflict with the
provisions set forth in this Security, the former shall control for purposes of this Security. 
 This Security is one of the series
designated on the face hereof, limited to a principal amount of $1,000,000,000, which amount may be increased at the option of the Company without the consent of the Holders of the Securities of this Series. References herein to “this
series” mean the series designated on the face hereof. 
 This Security may be redeemed in certain circumstances at the option of
the Company as set forth in the Indenture. 
 This Security may be automatically converted into Ordinary Shares or other securities of the
Company as set forth in the Indenture. 
 Subject to applicable law, no Holder of this Security may exercise, claim or plead any right of set-off, compensation or retention in respect of any amount owed to it by the Company arising under, or in connection with, the Securities and each Holder of Securities shall, by virtue of its holding of any
Securities, be deemed to have waived all such rights of set-off, compensation or retention. 
 The
Indenture permits, with certain exceptions as therein provided, the amendment thereof and the modification of the rights and obligations of the Company and the rights of the Holders of the Securities of each series to be affected under the Indenture
at any time by the Company and the Trustee with the consent of the Holders of a majority in principal amount of the Securities then Outstanding of each series to be affected. The Indenture also contains provisions permitting the Holders of a
majority in aggregate principal amount of the Securities of each series then Outstanding, on behalf of the Holders of all Securities of such series, to waive compliance by the Company with certain provisions of the Indenture and certain past
Defaults under the Indenture and their consequences. Any such consent or waiver by the Holder of this Security shall be conclusive and binding upon such Holder and upon all future Holders of this Security and of any Security issued upon the
registration of transfer hereof or in exchange herefor or in lieu hereof, whether or not notation of such consent or waiver is made upon this Security. 

As provided in and subject to the provisions of the Indenture, the Holder of this Security shall not have any right to institute any
proceeding, judicial or otherwise, with respect to the Indenture or for the appointment of a receiver or trustee or for any other remedy thereunder, unless such Holder shall have previously given the Trustee written notice of a continuing Event of
Default with respect to the Securities of this series, the Holders of not less than 25% in aggregate principal amount of the Securities of this series then Outstanding shall have made written request to the Trustee to institute proceedings in
respect of such Event of Default as Trustee and offered to the Trustee security or indemnity satisfactory to the 

  
 A-2-4 

 Exhibit A-2 
  

 
Trustee in its sole discretion against the costs, expenses and liabilities to be incurred in compliance with such request, the Trustee shall not have received from the Holders of a majority in
principal amount of Securities of this series then Outstanding a direction inconsistent with such request, and shall have failed to institute any such proceeding, for sixty (60) days after receipt of such notice, request and offer of indemnity.

 Notwithstanding any contrary provisions in this Security, nothing shall impair the right of a Holder of this Security under the Trust
Indenture Act, absent such Holder’s consent, to sue for any payments due but unpaid with respect to this Security. 
 As provided in
the Indenture and subject to certain limitations therein set forth, the transfer of this Security is registrable in the Security Register, upon surrender of this Security for registration of transfer at the office or agency of the Company in any
place where the principal of this Security is payable, duly endorsed by, or accompanied by a written instrument of transfer in form satisfactory to the Company and the Security Registrar duly executed by, the Holder hereof or his attorney duly
authorized in writing. Thereupon one or more new Securities of this series and of like tenor, of authorized denominations and for the same aggregate principal amount, will be issued to the designated transferee or transferees. 

The Securities of this series are issuable only in registered form without coupons in denominations of $200,000 and integral multiples of
$1,000 in excess thereof. As provided in the Indenture and subject to certain limitations therein set forth, Securities are exchangeable for a like aggregate principal amount of Securities of a different authorized denomination, as requested by the
Holder surrendering the same. 
 No service charge shall be made for any such registration of transfer or exchange, but the Company may
require payment of a sum sufficient to cover any tax or other governmental charge payable in connection therewith. 
 Prior to due
presentment of this Security for registration of transfer, the Company, the Trustee and any agent of the Company or the Trustee may treat the Person in whose name this Security is registered as the owner hereof for all purposes, whether or not this
Security be overdue, and neither the Company, the Trustee nor any such agent shall be affected by notice to the contrary. 
 All terms used
in this Security which are defined in the Indenture shall have the meanings assigned to them in the Indenture. 
 Dutch Bail-in Power. 
  

	 	(i)	 Notwithstanding any other agreements, arrangements or understandings between the Company and any holder or
beneficial owner of the Securities, by acquiring the Securities, the Holder and each Beneficial Owner of this Security, or any interest therein, acknowledges, accepts, recognizes, agrees to be bound by, and consents to the exercise of, any Dutch Bail-in Power by the Relevant Resolution Authority that may result in the reduction (including to zero), cancellation or write-down (whether on a permanent basis or subject to
write-up by the resolution authority) of all, or a portion, of the principal amount of, or interest on, the Securities and/or the conversion of all, or a portion of, the principal amount of, or interest on,
the Securities into shares or claims which may give right to shares or other instruments of ownership or other securities or other obligations of the Company or obligations of another person (whether or not at the point of non-viability and independently of or in combination with a resolution action), including by means of a variation to the terms of the Securities (which may include amending the interest amount or the maturity or
interest payment dates, including by suspending payment for a 

  
 A-2-5 

 Exhibit A-2 
  

	 	
temporary period), or that the Securities must otherwise be applied to absorb losses, or any expropriation of the Securities, in each case, to give effect to the exercise by the Relevant
Resolution Authority of such Dutch Bail-in Power (whether at the point of non-viability or as taken together with a resolution action). The Holder and each Beneficial
Owner of this Security or any interest therein further acknowledges and agrees that the rights of Holders and Beneficial Owners of the Securities or any interest therein are subject to, and will be varied, if necessary, so as to give effect to, the
exercise of any Dutch Bail-in Power by the Relevant Resolution Authority. For the avoidance of doubt, the potential conversion of the Securities into shares, other securities or other obligations in connection
with the exercise of any Dutch Bail-in Power by the Relevant Resolution Authority is separate and distinct from a Conversion following a Trigger Event. In addition, by acquiring any Securities, the Holder and
each Beneficial Owner of this Security or any interest therein further acknowledges, agrees to be bound by, and consents to the exercise by the Relevant Resolution Authority of, any power to vary the terms of the Securities, which may include
amending the Interest Payment Dates or amount, or to suspend any payment in respect of the Securities for a temporary period. 

  

	 	(ii)	 By its acquisition of the Securities, such Holder and Beneficial Owner: 

 

	 	(a)	 acknowledges and agrees that no exercise of the Dutch Bail-in Power by
the Relevant Resolution Authority with respect to the Securities or cancellation or deemed cancellation of interest on the Securities pursuant to Sections 2.03 and 2.04 of the Fourth Supplemental Indenture shall give rise to a default for purposes
of Section 315(b) (Notice of Default) and Section 315(c) (Duties of the Trustee in Case of Default) of the Trust Indenture Act; 

  

	 	(b)	 to the extent permitted by the Trust Indenture Act, waives any and all claims against the Trustee for, agrees
not to initiate a suit against the Trustee in respect of, and agrees that the Trustee shall not be liable for, any action that the Trustee takes, or abstains from taking, in either case in accordance with the exercise of the Dutch Bail-in Power by the Relevant Resolution Authority with respect to the Securities; 

  

	 	(c)	 acknowledges and agrees that, upon the exercise of any Dutch Bail-in
Power by the Relevant Resolution Authority, (i) the Trustee shall not be required to take any further directions from Holders or Beneficial Owners of the Securities under Section 5.12 of the Base Indenture and (ii) the Indenture shall
impose no duties upon the Trustee whatsoever with respect to the exercise of any Dutch Bail-in Power by the Relevant Resolution Authority. If Holders or Beneficial Owners of the Securities have given a
direction to the Trustee pursuant to Section 5.12 of the Base Indenture prior to the exercise of any Dutch Bail-in Power by the Relevant Resolution Authority, such direction shall cease to be of further
effect upon such exercise of any Dutch Bail-in Power and shall become null and void at such time. Notwithstanding the foregoing, if, following the completion of the exercise of the Dutch Bail-in Power by the Relevant Resolution Authority, the Securities remain outstanding, then the Trustee’s duties under the Indenture shall remain applicable with respect to the Securities following such
completion to the extent that the Company and the Trustee shall agree pursuant to a supplemental indenture or an amendment to this Fourth Supplemental Indenture; and 

 

	 	(d)	 (i) consents to the exercise of any Dutch Bail-in Power as it may be
imposed without any prior notice by the Relevant Resolution Authority of its decision to exercise such power with respect to the Securities and (ii) authorizes, directs and requests DTC and

  
 A-2-6 

 Exhibit A-2 
  

	 	
any direct participant in DTC or other intermediary through which it holds such Securities to take any and all necessary action, if required, to implement (x) the Conversion and (y) the
exercise of any Dutch Bail-in Power with respect to the Securities as it may be imposed, without any further action or direction on the part of such Holder and such Beneficial Owner. 

 

	 	(iii)	 By its acquisition of the Securities, such Holder and Beneficial Owner: 

 

	 	a)	 consents to the Conversion of its Securities following a Trigger Event and consents to the appointment of the
Conversion Shares Depository and the issuance of the Conversion Shares to the Conversion Shares Depository, all of which may occur without any further action on the part of such Holder or Beneficial Owner or the Trustee. To the extent the Securities
are held in the form of global securities, such Holder or Beneficial Owner authorizes, directs and requests DTC, any direct participant therein and any other intermediary through which it holds such Securities to take any and all necessary action,
if required, to implement the Conversion without any further action or direction on the part of such Holder or Beneficial Owner or the Trustee. 

  

	 	b)	 acknowledges and agrees that (a) interest is payable solely at the discretion of the Company, and no
amount of interest shall become due and payable in respect of the relevant Interest Payment Date or related Interest Period or redemption date to the extent that it has been cancelled or deemed cancelled (in whole or in part) by the Company in its
sole discretion and/or as a result of (i) the Company having insufficient Distributable Items, (ii) the relevant interest payment’s causing the Maximum Distributable Amount to be exceeded, or (iii) a Trigger Event or a
Liquidation Event having occurred; and (b) a cancellation or deemed cancellation of interest (in each case, in whole or in part) in accordance with the terms of this Fourth Supplemental Indenture shall not constitute a default in payment or
otherwise under the terms of the Securities. 

  

	 	c)	 unconditionally and irrevocably agrees to each and every provision of this Fourth Supplemental Indenture and
the Securities and waives, to the fullest extent permitted by the Trust Indenture Act and any other applicable law, any and all claims against the Trustee arising out of its acceptance of its trusteeship for the Securities, including, without
limitation, claims related to or arising out of or in connection with a Trigger Event and/or any Conversion. 

  

	 	d)	 acknowledges and agrees that all authority conferred or agreed to be conferred by any Holder or Beneficial
Owner pursuant to the provisions described above shall be binding upon the successors, assigns, heirs, executors, administrators, trustees in bankruptcy and legal representatives of each Holder or Beneficial Owner of a Security or any interest
therein. 

  

	 	(iv)	 No repayment of the principal amount of the Securities or payment of interest on the Securities shall be come
due and payable after the exercise of any Dutch Bail-in Power by the Relevant Resolution Authority unless such repayment or payment would be permitted to be made by the Company under the laws and regulations
of The Netherlands and the European Union applicable to the Company. 

  
 A-2-7 

 Exhibit A-2 
  

	 	(v)	 Upon the exercise of the Dutch Bail-in Power by the Relevant Resolution Authority with respect to this
Security, the Company shall provide a written notice of such event to DTC for the purposes of notifying the Holder of this Security or any interest therein of such occurrence, including the amount of any cancellation of all, or a portion, of the
principal amount of, or interest on, this Security, with a copy to the Trustee for information purposes, as soon as practicable regarding such exercise of the Dutch Bail-in Power. Failure to provide such notices will not have any impact on the
effectiveness of, or otherwise invalidate, any such exercise of the Dutch Bail-in Power. 

  

	 	(vi)	 Subsequent Investors’ Agreement. Holders or Beneficial Owners of Securities that acquire them in
the secondary market shall be deemed to acknowledge, agree to be bound by and consent to the same provisions specified herein to the same extent as the Holders or Beneficial Owners of the Securities that acquire the Securities upon their initial
issuance, including, without limitation, with respect to the acknowledgement and agreement to be bound by and consent to the terms of the Securities, including in relation to interest cancellation, the Conversion, the Dutch Bail-in Power and the limitations on remedies specified in the Indenture. 

  

	 	(vii)	 Conversion Upon a Trigger Event. Such Holder or Beneficial Owner consents to the Conversion of this
Security following a Trigger Event, the appointment of the Conversion Shares Depository, and the issuance of the Conversion Shares to the Conversion Shares Depository, all of which may occur without any further action on the part of such Holder or
Beneficial Owner or the Trustee, and following which no Holder or Beneficial Owner of this Security will have any rights against the Company with respect to the payment of principal of, or interest on, such Securities. To the extent this Security is
held in the form of a Global Security, such Holder or Beneficial Owner, directs and requests the Depositary, any direct participant therein and any other intermediary through which it holds such Securities to take any and all necessary action, if
required, to implement the Conversion without any further action or direction on the part of such Holder or Beneficial Owner or the Trustee. Upon a Trigger Event and Conversion, the principal amount of the Securities may be applied in such manner as
the Company deems necessary in connection with the issue and paying up of the relevant Conversion Shares and the delivery thereof to the Conversion Shares Depository or pursuant to any Alternative Delivery Arrangements. 

 

	 	(viii)	 Interest Cancellation. Interest shall be payable on this Security solely at the discretion of the
Company, and no amount of interest shall become due and payable in respect of the relevant Interest Payment Date or related Interest Period or Redemption Date to the extent that it has been cancelled or deemed cancelled (in whole or in part) by the
Company in its sole discretion and/or as a result of (i) the Company having insufficient Distributable Items, (ii) the relevant interest payment’s causing the Maximum Distributable Amount to be exceeded, or (iii) a Trigger Event
or Liquidation Event having occurred. A cancellation or deemed cancellation of interest (in each case, in whole or in part) in accordance with the terms of the Indenture shall not constitute a default in payment or otherwise under the terms of this
Security. 

  

	 	(ix)	 Waiver of Claims. Such Holder or Beneficial Owner unconditionally and irrevocably agrees to each and
every provision of the Indenture and this Security waives, to the fullest extent permitted by the Trust Indenture Act and any other applicable law, any and all claims against the Trustee arising out of its acceptance of its trusteeship for the
Securities, including, without limitation, claims related to or arising out of or in connection with a Trigger Event and/or any Conversion. 

  

	 	(x)	 Successors and Assigns. All authority conferred or agreed to be conferred by the Holder or Beneficial
Owner of this Security shall be binding upon the successors, assigns, heirs, executors, administrators, trustees in bankruptcy and legal representatives of such Holder or Beneficial Owner. 

  
 A-2-8 

 Exhibit B 

Form of Conversion Notice1 

CONVERSION NOTICE 
 [ING
Letterhead] 
 [Date] 
  

	To:	 Each Holder and Beneficial Owner of ING Groep N.V. [$1,000,000,000 3.875% Perpetual Additional Tier 1
Contingent Convertible Capital Securities (CUSIP: 456837AY9, ISIN: US456837AY94) / $1,000,000,000 4.250% Perpetual Additional Tier 1 Contingent Convertible Capital Securities (CUSIP: 456837AZ6, ISIN: US456837AZ69)] 

This notice is given by ING Groep N.V. (the “Company”) in connection with its [$1,000,000,000 3.875% Perpetual Additional Tier 1 Contingent
Convertible Capital Securities (CUSIP: 456837AY9, ISIN: US456837AY94) / $1,000,000,000 4.250% Perpetual Additional Tier 1 Contingent Convertible Capital Securities (CUSIP: 456837AZ6, ISIN: US456837AZ69)] issued on September 14, 2021 (the
“Securities”) pursuant to the Capital Securities Indenture, dated April 16, 2015, between the Company and The Bank of New York Mellon, London Branch, as Trustee (the “Trustee”), as supplemented by the Fourth
Supplemental Indenture, dated September 14, 2021, between the Company and the Trustee (together, the “Indenture”). Capitalized terms used herein and not defined herein shall have the respective meanings ascribed to such terms in the
Indenture. 
  

	 	1.	 A Trigger Event has occurred with respect to the Securities. 

 

	 	2.	 The Conversion Date is [•]. 

 

	 	3.	 The Company has appointed [•] as the Conversion Shares Depository. 

 

	 	4.	 The Conversion Price is $[•]. 

 

	 	5.	 The Conversion Shares shall be issued in the form of ordinary shares, par value €[•] per share, of
the Company (“Ordinary Shares”). 

  

	 	6.	 The Company expects The Depository Trust Company to suspend all clearance and settlement of the Securities on
[•]. 

  

	 	7.	 Each Holder or Beneficial Owner of a Security or an interest therein is required to complete a Conversion
Shares Settlement Notice in the form attached as Annex A hereto and deliver it to the Conversion Shares Depository not later than [•] (the “Notice Cut-Off Date”).

  

	 	8.	 Securities for which no Conversion Shares Settlement Notice has been received by the Conversion Shares
Depository shall be cancelled on [•] (the “Final Cancellation Date”). 

  

	 	9.	 The Securities shall remain in existence for the sole purpose of evidencing the holder’s right to receive
Conversion Shares from the Conversion Shares Depository. 

  

	1 	 Form to be used for either tranche. 

  
 B-1 

 Exhibit B 
  

 If a Holder or Beneficial Owner of Securities properly completes and delivers a Conversion Shares Settlement
Notice on or before the Notice Cut-Off Date, the Conversion Shares Depository shall, in accordance with the terms of the Indenture, deliver to such Holder or Beneficial Owner the relevant Conversion Shares
(rounded down to the nearest whole number of Conversion Shares) two (2) Business Days after the date on which the Conversion Shares Settlement Notice is received by the Conversion Shares Depository. 

If a Holder or Beneficial Owner of Securities fails to properly complete and deliver a Conversion Shares Settlement Notice before the Notice Cut-Off Date, the Conversion Shares Depository shall continue to hold the relevant Conversion Shares. However, the relevant Securities shall be cancelled on the Final Cancellation Date. Any Holder or Beneficial
Owner of Securities delivering a Conversion Shares Settlement Notice after the Notice Cut-Off Date must provide evidence of its entitlement to the relevant Conversion Shares satisfactory to the Conversion
Shares Depository in its sole and absolute discretion in order to receive such Conversion Shares. 
 For inquiries, please contact: 

[ING Contact Person] 

[Telephone] 
 [Fax]

 [Email] 

  
 B-2 

 Exhibit C 

Form of Conversion Shares Settlement Notice2 

CONVERSION SHARES SETTLEMENT NOTICE 
  

					
	To:	  	The Depository Trust Company 
55 Water Street, 25th Floor 
New York, NY 10041-0099 
Attn: Mandatory Reorganization Department 
Fax: +1 (212) 855-5488 
Email:
mandatoryreorgannouncements@dtcc.com	  	[Contact details of [Conversion Shares Depository] to be included.]
			
	Cc:	  	 The Bank of New York Mellon
 Merck House

Seldown
 Poole, Dorset BH15 1PX

United Kingdom 
Attn: International Corporate Trust Services

Email: corpsov2@bnymellon.com
 Fax: 01202 689600

Tel: 01202 689978
	  	The Bank of New York Mellon 
101 Barclay Street 
Floor 7-E 
New York, New York 10286 
United States of America 
Attn: International Corporate Trust 
Fax: +1 (212) 815-5366

  

	Re:	 ING Groep N.V. [$1,000,000,000 3.875% Perpetual Additional Tier 1 Contingent Convertible Capital Securities
(CUSIP: 456837AY9, ISIN: US456837AY94 / $1,000,000,000 4.250% Perpetual Additional Tier 1 Contingent Convertible Capital Securities (CUSIP: 456837AZ6, ISIN: US456837AZ69)] (the “Securities”) 

Reference is made to the Capital Securities Indenture, dated April 16, 2015, between ING Groep N.V. and The Bank of New York Mellon, London Branch, as
Trustee (“Trustee”), as supplemented by the Fourth Supplemental Indenture, dated September 14, 2021, between the Company and the Trustee (together, the “Indenture”). Capitalized terms used herein and not defined
herein shall have the respective meanings ascribed to such terms in the Indenture. 
 The person submitting this Notice hereby represents and warrants, for
the benefit of the Company and the Conversion Shares Depository, that the Holder or Beneficial Owner on whose behalf this Notice is submitted is entitled to take delivery of the Conversion Shares and has obtained any consents necessary in order to
do so. 
  

			
	 
	
INFORMATION OF THE HOLDER OR BENEFICIAL OWNER FOR DELIVERY OF

CONVERSION SHARES

	Surname/Company Name	  	First name
	Name to be entered in share register

  

	2 	 Form to be used for either tranche. 

  
 C-1 

			
	Tradable Amount of the Securities held on the date hereof
	Euroclear Netherlands or DTC participant ID	  	Euroclear Netherlands member account (if applicable)
	Indicate here if Conversion Shares are to be issued in
the form of American Depositary Shares:
	[Account details of clearing system account]3
	[Address to which any Conversion Shares should be
delivered]4

 YOU MUST DELIVER THE CONVERSION SHARES SETTLEMENT NOTICE TO THE CONVERSION SHARES DEPOSITORY AND THE TRUSTEE VIA DTC BEFORE
[INSERT FINAL CANCELLATION DATE]. 
 If you fail to properly complete and deliver the Conversion Shares Settlement Notice on or
before [INSERT NOTICE CUT-OFF DATE], the Conversion Shares Depository shall continue to hold your Conversion Shares. However, your Securities shall be cancelled on [INSERT FINAL CANCELLATION
DATE], and you will have to provide evidence of your entitlement to the relevant Conversion Shares satisfactory to the Conversion Shares Depository in its sole and absolute discretion in order to receive delivery of such Conversion Shares. 

 

	3 	 Note: To be included if the Conversion Shares will be delivered through a clearing system account
other than Euroclear Netherlands or DTC. 

	4 	 Note: To be included if the Conversion Shares are not a participating security in Euroclear
Netherlands, DTC or any another clearing system. 

  
 C-2Exhibit
4.6

 

[CERTAIN
INFORMATION IN THIS EXHIBIT IDENTIFIED BY [***] IS CONFIDENTIAL AND HAS BEEN EXCLUDED BECAUSE IT IS (I) NOT MATERIAL AND (II) THE REGISTRANT
CUSTOMARILY AND ACTUALLY TREATS THAT INFORMATION AS PRIVATE OR CONFIDENTIAL.]

 

THIS
WARRANT AND THE SHARES ISSUABLE HEREUNDER HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES
ACT”), OR THE SECURITIES LAWS OF ANY STATE AND, EXCEPT AS SET FORTH IN SECTIONS 5.3 AND 5.4 BELOW, MAY NOT BE OFFERED, SOLD,
PLEDGED OR OTHERWISE TRANSFERRED UNLESS AND UNTIL REGISTERED UNDER SAID ACT AND LAWS OR, IN THE OPINION OF LEGAL COUNSEL IN FORM AND
SUBSTANCE SATISFACTORY TO THE COMPANY, SUCH OFFER, SALE, PLEDGE OR OTHER TRANSFER IS EXEMPT FROM SUCH REGISTRATION.

 

WARRANT
TO PURCHASE ORDINARY SHARES

 

	Company:	 	4D
    PHARMA PLC, a public limited company incorporated in England and Wales with company number 08840579
	Number
    of Shares:	 	110,535
    ordinary shares of 0.25 pence each (“Ordinary Shares”) 
	 	 	 
	Type/Series
    of Shares:	 	Ordinary
    Shares
	Warrant
    Price:	 	US
    $1.18 per Ordinary Share
	Issue
    Date:	 	July
    29, 2021
	Expiration
    Date:	 	July
    29, 2026 See also Section 5.1(b).
	Credit
    Facility:	 	This
    Warrant to Purchase Shares (“Warrant”) is issued in connection with that certain
	 	 	Loan
    and Security Agreement of even date herewith among OXFORD FINANCE LUXEMBOURG S.À R.L., acting in respect of its Compartment
    4, a Luxembourg private limited liability company (société à responsabilité limitée) with registered
    office at 2 route d’Arlon, 8008 Strassen, Grand Duchy of Luxembourg and registered with the Luxembourg commercial register
    under number B243395, as Lender and Collateral Agent, the Lenders from time to time party thereto, and the Company and other borrowers
    party thereto (as modified, amended and/or restated from time to time, the “Loan Agreement”).

 

THIS
WARRANT CERTIFIES THAT, for good and valuable consideration, OXFORD FINANCE LUXEMBOURG S.À R.L., a Luxembourg private limited
liability company (société à responsabilité limitée) with registered office at 2 route d’Arlon,
8008 Strassen, Grand Duchy of Luxembourg and registered with the Luxembourg commercial register under number B243395, acting in respect
of its Compartment 4 (“Oxford” and, together with any successor or permitted assignee or transferee of this Warrant
or of any shares issued upon exercise hereof, “Holder”) is entitled to purchase the number of fully paid and non-assessable
Ordinary Shares of the above-stated Type/Series of shares (the “Class”) of the above-named company (the “Company”)
at the above-stated Warrant Price, all as set forth above and as adjusted pursuant to Section 2 of this Warrant, subject to the provisions
and upon the terms and conditions set forth in this Warrant.

 

SECTION
1. EXERCISE.

 

1.1 Method
of Exercise. Holder may at any time and from time to time exercise this Warrant, in whole or in part, by delivering to
the Company the original of this Warrant together with a duly executed Notice of Exercise in substantially the form attached hereto
as Appendix 1 and, unless Holder is exercising this Warrant pursuant to a cashless exercise set forth in Section 1.2, a check, wire
transfer of same-day funds (to an account designated by the Company), or other form of payment acceptable to the Company and/ or by
way of release of the Company for a liquidated sum for the aggregate Warrant Price for the Ordinary Shares being purchased.

 

    	1

    	 

    

 

1.2 Cashless
Exercise. On any exercise of this Warrant, in lieu of payment of the aggregate Warrant Price in the manner as specified in
Section 1.1 above, but otherwise in accordance with the requirements of Section 1.1, Holder may elect to receive Ordinary Shares
equal to the value of this Warrant, or portion hereof as to which this Warrant is being exercised. Thereupon, the Company shall
issue to the Holder such number of fully paid and non-assessable Ordinary Shares as are computed using the following
formula:

 

X
= Y(A-B)/A

 

where:

 

	 	X
    =	the
    number of Ordinary Shares to be issued to the Holder;
	 	 	 
	 	Y
    =	the
    number of Ordinary Shares with respect to which this Warrant is being exercised (inclusive of the Ordinary Shares surrendered to
    the Company in payment of the aggregate Warrant Price);
	 	 	 
	 	A
    =	the
    Fair Market Value (as determined pursuant to Section 1.3 below) of one Ordinary Share; and
	 	B
    =	the
    Warrant Price.

 

To
the extent that the Company is prohibited from issuing Ordinary Shares following an election for cashless exercise pursuant to this Section
1.2, whether by virtue of the United Kingdom Companies Act 2006 (the “Companies Act”) or otherwise, the relevant Holder
shall be entitled to subscribe at nominal value for the Ordinary Shares to which it would otherwise have been entitled to receive this
Section 1.2.

 

1.3
Fair Market Value. Subject to Section 1.6(c), if the Company’s Ordinary Shares are then traded or quoted on the AIM market
or (if not on AIM) on a nationally recognized securities exchange, inter-dealer quotation system or over-the-counter market (a “Trading
Market”), the fair market value of an Ordinary Share shall be the closing price or last sale price of an ordinary share reported
for the Business Day immediately before the date on which Holder delivers this Warrant together with its Notice of Exercise to the Company.
If the Company’s Ordinary Shares are then not traded or quoted on a Trading Market but American Depositary Shares (“ADSs”)
representing the Ordinary Shares of the Company are then traded on a Trading Market, the fair market value of an Ordinary Share shall
be the closing price or last sale price of an ADS reported for the Business Day immediately before the date on which Holder delivers
this Warrant together with its Notice of Exercise to the Company divided by the number of the Company’s Ordinary Shares represented
by one ADS. If neither the Company’s Ordinary Shares nor ADSs are then traded on a Trading Market, the Board of Directors of the
Company shall determine the fair market value of an Ordinary Share in its reasonable good faith judgment.

 

1.4
Delivery of Certificate and New Warrant. Within a reasonable time after Holder exercises this Warrant in the manner set forth
in Section 1.1 or 1.2 above, the Company shall deliver to Holder a certificate representing the Ordinary Shares issued to Holder upon
such exercise and, if this Warrant has not been fully exercised and has not expired, a new warrant of like tenor representing the Ordinary
Shares not so acquired.

 

1.5
Replacement of Warrant. On receipt of evidence reasonably satisfactory to the Company of the loss, theft, destruction or mutilation
of this Warrant and, in the case of loss, theft or destruction, on delivery of an indemnity agreement reasonably satisfactory in form,
substance and amount to the Company or, in the case of mutilation, on surrender of this Warrant to the Company for cancellation, the
Company shall, within a reasonable time, execute and deliver to Holder, in lieu of this Warrant, a new warrant of like tenor and amount.

 

1.6
Treatment of Warrant Upon Acquisition of Company.

 

(a)
Acquisition. For the purpose of this Warrant, “Acquisition” means any transaction or series of related transactions
involving: (i) an offer being made to all (or as nearly as may be practicable all) of the Company’s shareholders (or all (or as
nearly as may be practicable all) such shareholders other than the offeror(s) and/or any associate (as defined in Section 988(1) of the
Act) of the offeror(s)), to acquire all or a majority of the issued ordinary share capital of the Company (an “Offer”)
or (ii) a scheme of arrangement or analogous proceeding with regard to such acquisition which if it becomes effective will result in
right to cast more than 50 per cent. of the votes which may ordinarily be cast on a poll at a general meeting of the Company becoming
unconditionally vested in the offeror(s) or such person, as the case may be and/or any associate (as defined in Section 988(1) of the
Companies Act) of the offeror(s) or such person, as the case may be (a “Scheme”) .

 

    	2

    	 

    

 

(b)
 Treatment of Warrant at Acquisition. The Company shall not recommend (i) an Offer or (ii) a Scheme unless the offeror
makes an appropriate offer or proposal to each Holder to ensure that their interests are safeguarded and for these purposes the Company
shall procure that all forms of consideration offered to holders of Ordinary Shares in the Offer or the Scheme shall be extended to each
Holder.

 

(c) Any
Warrants which are not exercised or exchanged while the Offer remains open for acceptance or before the Scheme becomes effective (as
the case may) shall deemed to be automatically exercised pursuant to Section 1.2 if Warrant Price is less than the consideration per
Ordinary Share in the Offer or the Scheme prior to the Offer closing (assuming the Offer becomes unconditional in all respects and
the contemplated transactions consummated) or the Scheme becoming effective and for the purposes of Section 1.2, “Fair
Value” shall be the price per Ordinary Share offered by the offeror in the Offer or the Scheme (as the case may
be).

 

(d)
 Delivery of ADSs representing Ordinary Shares. If (i) the Ordinary Shares issued upon exercise of this Warrant in accordance
with its terms are not “restricted securities” (as defined in Rule 144 promulgated under the Securities Act) and are not
otherwise subject to any restriction on being deposited with the Depositary pursuant to the terms of the ADS Deposit Agreement and (ii)
the Holder of this Warrant requests that the Company deliver ADSs representing such Ordinary Shares, the Company will, at its sole cost,
promptly use its commercially reasonable efforts to deliver such Ordinary Shares to the Depositary for the ADSs and request that the
Depositary promptly issue and deliver ADSs representing such Ordinary Shares to the Holder; provided that the Holder shall comply with
all requirements under the ADSs Deposit Agreement.

 

SECTION
2. ADJUSTMENTS TO THE ORDINARY SHARES AND WARRANT PRICE.

 

2.1 Ordinary
Share Dividends, Splits, Etc. If the Company declares or pays a dividend or distribution on the outstanding shares of the
Class payable in ordinary shares or other securities or property (other than cash), then upon exercise of this Warrant, for each
Ordinary Share acquired, Holder shall receive, without additional cost to Holder, the total number and kind of securities and
property which Holder would have received had Holder owned the Ordinary Shares of record as of the date the dividend or distribution
occurred. If the Company subdivides the outstanding shares of the Class by reclassification or otherwise into a greater number of
shares, the number of Ordinary Shares purchasable hereunder shall be proportionately increased and the Warrant Price shall be
proportionately decreased. If the outstanding shares of the Class are combined or consolidated, by reclassification or otherwise,
into a lesser number of shares, the Warrant Price shall be proportionately increased and the number of Ordinary Shares shall be
proportionately decreased.

 

2.2 Reclassification,
Exchange, Combinations or Substitution. Upon any event whereby all of the outstanding shares of the Class are
reclassified, exchanged, combined, substituted, or replaced for, into, with or by Company securities of a different class and/or
series, then from and after the consummation of such event, this Warrant will be exercisable for the number, class and series of
Company securities that Holder would have received had the Ordinary Shares been outstanding on and as of the consummation of such
event, and subject to further adjustment thereafter from time to time in accordance with the provisions of this Warrant. The
provisions of this Section 2.2 shall similarly apply to successive reclassifications, exchanges, combinations substitutions,
replacements or other similar events.

 

2.3 No
Fractional Ordinary Share. No fractional Ordinary Share shall be issuable upon exercise of this Warrant and the number of
Ordinary Shares to be issued shall be rounded down to the nearest whole Ordinary Share. If a fractional Ordinary Share interest
arises upon any exercise of the Warrant, the Company shall eliminate such fractional Ordinary Share interest by paying Holder in
cash the amount computed by multiplying the fractional interest by (i) the fair market value (as determined in accordance with
Section 1.3 above) of a full Ordinary Share, less (ii) the then-effective Warrant Price

 

2.4 Notice/Certificate
as to Adjustments. Upon each adjustment of the Warrant Price, Class and/or number of Ordinary Shares, the Company, at the
Company’s expense, shall notify Holder in writing within a reasonable time setting forth the adjustments to the Warrant Price,
Class and/or number of Ordinary Shares and facts upon which such adjustment is based. The Company shall, upon written request from
Holder, furnish Holder with a certificate of its Chief Financial Officer, including computations of such adjustment and the Warrant
Price, Class and number of Ordinary Shares in effect upon the date of such adjustment.

 

    	3

    	 

    

 

SECTION
3. REPRESENTATIONS AND COVENANTS OF THE COMPANY. 

 

3.1
Representations and Warranties. The Company represents and warrants to, and agrees with, the Holder as follows:

 

(a)
All Ordinary Shares which may be issued upon the exercise of this Warrant, and all securities, if any, issuable upon conversion of the
Ordinary Shares, shall, upon issuance, be duly authorized, validly issued, fully paid and non-assessable, and free of any liens and encumbrances
except for restrictions on transfer provided for herein or under applicable federal and state securities laws.

 

(b)
(i) It has authority to grant this Warrant and (ii) it will at all times following the issue of the Warrant maintain authority to allot
such number of Ordinary Shares as is required to meet the exercise in full of the subscription rights attaching to all this Warrant.

 

3.2
Notice of Certain Events. If the Company proposes at any time to:

 

(a)
declare any dividend or distribution upon the outstanding shares of the Class or ordinary shares, whether in cash, property, shares,
or other securities and whether or not a regular cash dividend;

 

(b)
offer for subscription or sale pro rata to the holders of the outstanding shares of the Class any additional shares of any class or series
of the Company’s shares (other than pursuant to contractual pre-emptive rights);

 

(c)
effect any reclassification, exchange, combination, substitution, reorganization or recapitalization of the outstanding shares of the
Class; or

 

(d)
effect an Acquisition or to liquidate, dissolve or wind up; or then, in connection with each such event, the Company shall give
Holder:

 

(1)
at least a seven (7) Business Days prior written notice of the date on which a record will be taken for such dividend, distribution,
or subscription rights (and specifying the date on which the holders of outstanding shares of the Class will be entitled thereto) or
for determining rights to vote, if any, in respect of the matters referred to in (a) and (b) above; and

 

(2)
in the case of the matters referred to in (c) and (d) above at least seven (7) Business Days prior written notice of the date when the
same will become effective (and specifying the date on which the holders of outstanding shares of the Class will be entitled to exchange
their shares for the securities or other property deliverable upon the occurrence of such event).

 

Reference
is made to Section 1.6(c) whereby this Warrant will be deemed to be exercised pursuant to Section 1.2. The Company will also provide
information requested by Holder that is reasonably necessary to enable Holder to comply with Holder’s accounting or reporting requirements.

 

SECTION
4. REPRESENTATIONS, WARRANTIES OF THE HOLDER.

 

The
Holder represents and warrants to the Company as follows (and Holder shall be deemed to have restated each of the representations and
warranties set forth below as of the date of each exercise hereof):

 

4.1
Purchase for Own Account. This Warrant and the securities to be acquired upon exercise of this Warrant by Holder are being acquired
for investment for Holder’s account, not as a nominee or agent, and not with a view to the public resale or distribution within
the meaning of the Securities Act. Holder also represents that it has not been formed for the specific purpose of acquiring this Warrant
or the Ordinary Shares.

 

    	4

    	 

    

 

4.2 Disclosure
of Information. Holder is aware of the Company’s business affairs and financial condition and has received or has
had full access to all the information it considers necessary or appropriate to make an informed investment decision with respect to
the acquisition of this Warrant and its underlying securities. Holder further has had an opportunity to ask questions and receive
answers from the Company regarding the terms and conditions of the offering of this Warrant and its underlying securities and to
obtain additional information (to the extent the Company possessed such information or could acquire it without unreasonable effort
or expense) necessary to verify any information furnished to Holder or to which Holder has access.

 

4.3 Investment
Experience. Holder understands that the purchase of this Warrant and its underlying securities involves substantial risk.
Holder has experience as an investor in securities of companies in the development stage and acknowledges that Holder can bear the
economic risk of such Holder’s investment in this Warrant and its underlying securities and has such knowledge and experience
in financial or business matters that Holder is capable of evaluating the merits and risks of its investment in this Warrant and its
underlying securities and/or has a preexisting personal or business relationship with the Company and certain of its officers,
directors or controlling persons of a nature and duration that enables Holder to be aware of the character, business acumen and
financial circumstances of such persons.

 

4.4 Accredited
Investor Status. Holder is an “accredited investor” within the meaning of Regulation D promulgated under the
Securities Act.

 

4.5 The
Securities Act. Holder understands that this Warrant and the Ordinary Shares issuable upon exercise hereof have not been, and
will not be, registered under the Securities Act in reliance upon a specific exemption therefrom, which exemption depends upon,
among other things, the bona fide nature of the Holder’s investment intent as expressed herein. Holder understands that this
Warrant and the Ordinary Shares issued upon any exercise hereof must be held indefinitely unless subsequently registered under the
Securities Act and qualified under applicable state securities laws, or unless exemption from such registration and qualification
are otherwise available. Holder is aware of the provisions of Rule 144 promulgated under the Securities Act.

 

4.6 No
Voting Rights. Holder, as a Holder of this Warrant, will not have any voting rights until the exercise of this
Warrant.

 

SECTION
5. MISCELLANEOUS.

 

5.1
Term; Automatic Cashless Exercise Upon Expiration.

 

(a)
  Term. Subject to the provisions of Section 1.6 above, this Warrant is exercisable in whole or in part at any time and
from time to time on or before 6:00 PM Eastern United States time, on the Expiration Date and shall be void thereafter.

 

(b)  Automatic
Cashless Exercise upon Expiration. In the event that, upon the Expiration Date, the fair market value of one Ordinary Share (or
other security issuable upon the exercise hereof) as determined in accordance with Section 1.3 above is greater than the Warrant
Price in effect on such date, then this Warrant shall automatically be deemed on and as of such date to be exercised pursuant to
Section 1.2 above as to all Ordinary Shares (or such other securities) for which it shall not previously have been exercised, and
the Company shall, within a reasonable time, deliver a certificate representing the Ordinary Shares (or such other securities)
issued upon such exercise to Holder.

 

    	5

    	 

    

 

5.2 Legends.
Each certificate evidencing Ordinary Shares (and each certificate evidencing the securities issued upon conversion of any
Ordinary Shares, if any) shall be imprinted with a legend in substantially the following form:

 

THE
ORDINARY SHARES EVIDENCED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE
“ACT”), OR THE SECURITIES LAWS OF ANY STATE AND, EXCEPT AS SET FORTH IN THAT CERTAIN WARRANT TO PURCHASE
ORDINARY ORDINARY SHARES ISSUED BY THE ISSUER TO OXFORD FINANCE LUXEMBOURG S.À R.L., ACTING IN RESPECT OF ITS COMPARTMENT 4,
DATED JULY 29, 2021, MAY NOT BE OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED UNLESS AND UNTIL REGISTERED UNDER SAID ACT AND LAWS
OR, IN THE OPINION OF LEGAL COUNSEL IN FORM AND SUBSTANCE SATISFACTORY TO THE ISSUER, SUCH OFFER, SALE, PLEDGE OR OTHER TRANSFER IS
EXEMPT FROM SUCH REGISTRATION.

 

5.3 Compliance
with Securities Laws on Transfer. This Warrant and the Ordinary Shares issued upon exercise of this Warrant (and the securities
issuable, directly or indirectly, upon conversion of the Ordinary Shares, if any) may not be transferred or assigned in whole or in
part except in compliance with applicable federal and state securities laws by the transferor and the transferee (including, without
limitation, the delivery of investment representation letters and legal opinions reasonably satisfactory to the Company, as
reasonably requested by the Company). The Company shall not require Holder to provide an opinion of counsel if the transfer is to an
affiliate of Holder, provided that any such transferee is an “accredited investor” as defined in Regulation D
promulgated under the Securities Act. Additionally, the Company shall also not require an opinion of counsel if there is no question
as to the availability of Rule 144 promulgated under the Securities Act.

 

5.4 Transfer
Procedure. After receipt by Oxford of the executed Warrant, Oxford may transfer all or part of this Warrant to one or
more of Oxford’s affiliates (each, an “Oxford Affiliate”), by execution of an Assignment substantially in
the form of Appendix 2. Subject to the provisions of Article 5.3 and upon providing the Company with written notice, Oxford, any
such Oxford Affiliate and any subsequent Holder, may transfer all or part of this Warrant or the Shares issuable upon exercise of
this Warrant (or the Shares issuable directly or indirectly, upon conversion of the Shares, if any) to any other transferee,
provided, however, in connection with any such transfer, the Oxford Affiliate(s) or any subsequent Holder will give the Company
notice of the portion of the Warrant being transferred with the name, address and taxpayer identification number of the transferee
and Holder will surrender this Warrant to the Company for reissuance to the transferee(s) (and Holder if applicable).

 

5.5 Notices.
All notices and other communications hereunder from the Company to the Holder, or vice versa, shall be deemed delivered and
effective (i) when given personally, (ii) on the third (3rd) Business Day after being mailed by first-class registered or certified
mail, postage prepaid, (iii) upon actual receipt if given by electronic mail and such receipt is confirmed in writing by the
recipient, or (iv) on the first Business Day following delivery to a reliable overnight courier service, courier fee prepaid, in any
case at such address as may have been furnished to the Company or Holder, as the case may be, in writing by the Company or such
Holder from time to time in accordance with the provisions of this Section 5.5. All notices to Holder shall be addressed as follows
until the Company receives notice of a change of address in connection with a transfer or otherwise:

 

OXFORD
FINANCE LUXEMBOURG S.À R.L.

[***]

 

Notice
to the Company shall be addressed as follows until Holder receives notice of a change in address:

 

4D
PHARMA PLC

[***]

 

With
a copy (which shall not constitute notice) to:

 

Pinsent
Masons LLP

[***]

 

And

 

Wilson
Sonsini Goodrich & Rosati, P.C.

[***]

 

***
Certain information, as identified by [***], has been excluded from this agreement because it is both (i) not material and (ii)
would be competitively harmful if publicly disclosed.

 

    	6

    	 

    

 

5.6 Waiver.
This Warrant and any term hereof may be changed, waived, discharged or terminated (either generally or in a particular
instance and either retroactively or prospectively) only by an instrument in writing signed by the party against which enforcement
of such change, waiver, discharge or termination is sought.

 

5.7 Attorneys’
Fees. In the event of any dispute between the parties concerning the terms and provisions of this Warrant, the party
prevailing in such dispute shall be entitled to collect from the other party all costs incurred in such dispute, including
reasonable attorneys’ fees.

 

5.8 Counterparts;
Facsimile/Electronic Signatures. This Warrant may be executed in counterparts, all of which together shall constitute one and
the same agreement. Any signature page delivered electronically or by facsimile shall be binding to the same extent as an original
signature page with regards to any agreement subject to the terms hereof or any amendment thereto.

 

5.9 Governing
Law. This Warrant shall be governed by and construed in accordance with the laws of the State of California, without
giving effect to its principles regarding conflicts of law.

 

5.10 Headings.
The headings in this Warrant are for purposes of reference only and shall not limit or otherwise affect the meaning of any
provision of this Warrant.

 

5.11 Business
Days. “Business Day” is any day that is not a Saturday, Sunday or a day on which Oxford is closed.

 

[Remainder
of page left blank intentionally]

 

[Signature
page follows]

 

***
Certain information, as identified by [***], has been excluded from this agreement because it is both (i) not material and (ii)
would be competitively harmful if publicly disclosed.

 

    	7

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