Document:

Document

Exhibit 4.18

DESCRIPTION OF THE REGISTRANT’S SECURITIES
REGISTERED PURSUANT TO SECTION 12 OF THE
SECURITIES EXCHANGE ACT OF 1934
Intel Corporation (“Intel”) has one class of securities registered under Section 12 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”): our common stock, par value $0.001 per share (the “common stock”).
DESCRIPTION OF COMMON STOCK
The following summary description sets forth some of the general terms and provisions of the common stock. Because this is a summary description, it does not contain all of the information that may be important to you. For a more detailed description of the common stock, you should refer to the provisions of our third restated certificate of incorporation (the “certificate of incorporation”) and our bylaws, as amended and restated, each of which is an exhibit to the Annual Report on Form 10-K to which this description is an exhibit.
General
Under the certificate of incorporation, Intel is authorized to issue up to 10 billion shares of common stock with a par value of $0.001 per share and up to 50 million shares of preferred stock with a par value of $0.001 per shares (the “preferred stock”). The shares of common stock currently outstanding are fully paid and nonassessable.  No shares of preferred stock are currently outstanding. The Board of Directors has the authority to repeal, alter or amend the bylaws or adopt new bylaws, subject to certain limitations set forth in the bylaws.
No Preemptive, Redemption or Conversion Rights
The common stock is not redeemable, is not subject to sinking fund provisions, does not have any conversion rights and is not subject to call. Holders of shares of common stock have no preemptive rights to maintain their percentage of ownership in future offerings or sales of stock of Intel.
Voting Rights
Holders of shares of common stock have one vote per share in all elections of directors and on all other matters submitted to a vote of stockholders of Intel. Holders of shares of common stock do not have cumulative voting rights.
Board of Directors
Our board of directors is not classified. Our bylaws establish that the size of the whole Board of Directors shall be fixed from time to time by a duly adopted resolution of the Board of Directors. 
No Action by Stockholder Consent
The certificate of incorporation prohibits action that is required or permitted to be taken at any annual or special meeting of stockholders of Intel from being taken by the written consent of stockholders without a meeting.

Power to Call Special Stockholder Meeting
Under Delaware law, a special meeting of stockholders may be called by our board of directors or by any other person authorized to do so in the certificate of incorporation or bylaws. Pursuant to our bylaws, special meetings of the stockholders may be called, for any purpose or purposes, by the Chairman of the Board of Directors or the Chief Executive Officer or the Board of Directors at any time. In addition, a special meeting of the stockholders of Intel shall be called by the Board of Directors upon written request to the Corporate Secretary of one or more stockholders owning in the aggregate not less than fifteen percent (15%) of the outstanding shares entitled to vote on the matter or matters to be brought before the proposed special meeting.
Proxy Access Nominations
Under our bylaws, a stockholder (or a group of up to 20 stockholders) who has held at least 3% of our common stock for three years or more may nominate a director and have that nominee included in our proxy materials, provided that the stockholder and nominee satisfy the requirements specified in our bylaws. Any stockholder who intends to use these procedures to nominate a candidate for election to the Board of Directors for inclusion in our proxy statement must satisfy the requirements specified in our bylaws.
Dividend Rights
Subject to the preferences applicable to any outstanding shares of preferred stock, the holders of common stock are entitled to receive dividends, if any, as and when declared, from time to time, by our board of directors out of funds legally available therefor.
Liquidation, Dissolution or Similar Rights
Subject to the preferences applicable to any outstanding shares of preferred stock, upon liquidation, dissolution or winding up of the affairs of Intel, the holders of common stock will be entitled to participate equally and ratably, in proportion to the number of shares held, in the net assets of Intel available for distribution to holders of stock of Intel.
Forum Selection Clause
Under our bylaws, unless Intel consents in writing to the selection of an alternative forum, the sole and exclusive forum for making certain types of claims shall be the Delaware Court of Chancery (except that, in the event the Delaware Court of Chancery lacks subject matter jurisdiction over any such action or proceeding, then the sole and exclusive forum for such action or proceeding shall be the federal district court for the District of Delaware). This provision applies to (a) any derivative action or proceeding brought on behalf of Intel, (b) any action asserting a claim of breach of a fiduciary duty owed by any director, officer, employee or agent of Intel to Intel or our stockholders, including a claim alleging the aiding and abetting of such a breach of fiduciary duty, (c) any action asserting a claim arising pursuant to any provision of the Delaware General Corporation Law or Intel’s certificate of incorporation or bylaws, (d) any action asserting a claim governed by the internal affairs doctrine of the State of Delaware, or (e) any action asserting an “internal corporate claim” as that term is defined in Section 115 of the Delaware General Corporation Law.Exhibit 10.1

 

SUBSCRIPTION AGREEMENT

 

This Subscription Agreement
(this “Agreement”), dated as of January 27, 2022, has been entered into by and between the purchasers set forth
on the Omnibus Signature Pages hereto (each a “Purchaser” and together, the “Purchasers”)
and SmartKem, Inc., a Delaware corporation (the “Company”).

 

R E C I T A L S

 

A.        The
Company and the Purchasers have entered into that certain Letter Agreement, dated as of February 23, 2021(the “Letter Agreement”).

 

B.  Pursuant to the
Letter Agreement, the Purchasers have agreed, subject to the conditions set forth therein, to purchase an aggregate of 1,000,000 shares
(the “Shares”) of the Company’s common stock, par value $0.0001 per share (“Common Stock”),
at a purchase price of $2.00 per share (the “Per Share Purchase Price”), for an aggregate purchase price of
$2,000,000 (the “Offering”). (References herein to “dollar” or “$” are to United States
Dollars.)

 

C.   Each
Purchaser wishes to purchase, and the Company wishes to sell, upon the terms and conditions stated in this Agreement, that aggregate number
Shares set forth on each Purchaser’s Omnibus Signature Page hereto.

 

D.        The
Shares subscribed for pursuant to this Agreement have not been registered under the Securities Act of 1933, as amended, and the rules
and regulations promulgated thereunder (the “Securities Act”), or any state or foreign securities Law. The Offering
is being made to “accredited investors,” as defined in Regulation D under the Securities Act, in reliance upon the exemption
from securities registration afforded by Section 4(a)(2) of the Securities Act and Rule 506(b) of Regulation D. For purposes of this
Agreement, “Law” or “Laws” means any federal, state, local or foreign or provincial
statute, law (including, for the avoidance of doubt, any statutory, common, or civil law), ordinance, rule, regulation, order, injunction,
decree or agency requirement having the force of law or any undertaking to or agreement with any Governmental Authority (as defined below).

 

AGREEMENT

 

The Company and the Purchaser
hereby agree as follows:

 

1.      
Subscription.

 

(a)               
Purchase and Sale of the Shares.

 

(i)           
Each Purchaser, severally and not jointly, agrees to purchase, and the Company agrees to sell and issue to such Purchaser, that number
of Shares set forth on the Purchaser’s Omnibus Signature Page attached hereto at the Per Share Purchase Price for a total aggregate
purchase price (the “Purchase Price”) for the Shares as set forth on such Omnibus Signature Page.

 

     

     

    

 

(b)               
Closing.

 

(i)            Closing. The closing of the sale and purchase of the
Shares (the “Closing”) shall take place at 10:00 a.m., New York City time, on the date hereof (or such other
date and time as is mutually agreed to by the Company and each Purchaser) (the “Closing Date”) upon the satisfaction
(or waiver as provided herein) of the conditions set forth in this Section 1(b) (other than those conditions that by their nature will
be satisfied at the Closing, but subject to the satisfaction (or waiver as provided herein) of such conditions). The Closing shall take
place remotely via the exchange by electronic transmission of documents and signatures.

 

(ii)            Company Closing Deliveries. On or prior to the Closing Date,
the Company shall deliver or cause to be delivered to each Purchaser the following:

 

		a.	This Agreement, duly executed by the Company;

 

		b.	The registration rights agreement, substantially in the form of Exhibit A attached hereto
(the “Registration Rights Agreement”), duly executed by the Company.

 

		c.	A legal opinion from the Company’s counsel, in form and substance reasonably satisfactory to the
Purchasers;

 

		d.	Evidence of the book-entry issuance of the Shares purchased by such Purchaser hereunder; and

 

		e.	The Company’s wire transfer instructions.

 

(iii) Purchaser
Closing Deliveries. On or prior to the Closing Date, each Purchaser shall deliver or cause to be delivered to the Company the following:

 

		a.	This Agreement, duly executed by such Purchaser;

 

		b.	The Registration Rights Agreement, duly executed by such Purchaser; and

 

		c.	Such Purchaser’s Purchase Price.

 

2.      
Representations and Warranties of the Company. Except as set forth in the SEC Reports (as defined below), the Company
hereby represents and warrants to each Purchaser the following:

 

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(a)               
Organization and Qualification. The Company and each of its Subsidiaries is a corporation duly organized, validly existing
and in good standing under the Laws of the jurisdiction of its incorporation, and has the requisite corporate power to own, lease and
operate its properties and to carry on its business as currently conducted. The Company and each of its Subsidiaries is duly qualified
as a foreign corporation to do business and is in good standing in every jurisdiction in which the nature of the business as currently
conducted makes such qualification necessary, except to the extent that the failure to be so qualified or be in good standing would not
have a Material Adverse Effect. For purposes of this Agreement, “Material Adverse Effect” means any event, circumstance,
development, condition, occurrence, state of facts, change or effect that, individually or in the aggregate with any other event, circumstance,
development, condition, occurrence, state of facts, change or effect, has or would reasonably be expected to (x) prevent or materially
delay or materially impair the ability of the Company or its Subsidiaries to carry out its obligations under this Agreement or (y) have
any material adverse effect on the business, properties, assets, liabilities, operations or condition (financial or otherwise), results
of operations or future prospects of the Company and its Subsidiaries, taken as a whole; provided, however, that for purposes
of clause (y), none of the following shall be deemed in themselves, either alone or in combination, to constitute, and none of the following
shall be taken into account in determining whether there has been or would reasonably be expected to have a “Material Adverse Effect”:
(i) general financial, credit, capital market or regulatory conditions or any changes therein (provided, however, that such
effects do not affect the Company and its Subsidiaries taken as a whole disproportionately as compared to the Company’s competitors),
(ii) any effects alone or in combination that arise out of, or result from, directly or indirectly from the announcement, pendency, execution
or performance of this Agreement, the transactions contemplated hereby or any action contemplated by this Agreement, (iii) acts of God,
war (whether or not declared), disease, including the COVID 19 pandemic, the commencement, continuation or escalation of a war, acts of
armed hostility, sabotage or terrorism or other international or national calamity or any material worsening of such conditions (provided,
however, that such changes do not affect the Company or its Subsidiaries disproportionately as compared to the Company’s
competitors), (iv) any failure by the Company or its Subsidiaries to meet any projections, budgets or estimates of revenue or earnings
(it being understood that the facts giving rise to such failure may be taken into account in determining whether there has been a Material
Adverse Effect (except to the extent such facts are otherwise excluded from being taken into account by this proviso)), (v) changes affecting
the industry generally in which the Company or its Subsidiaries operates (provided, however, that such changes do not affect
the Company or its Subsidiaries disproportionately as compared to the Company’s competitors), or (vii) changes in Law or U.S. generally
accepted accounting principles (“GAAP”) (provided, however, that such changes do not affect the
Company or its Subsidiaries disproportionately as compared to the Company’s competitors). For purposes of this Agreement, “Subsidiary”
means, with respect to the Company, any corporation, partnership, limited liability company, joint venture or other legal entity of any
kind of which (i) 50% or more of the capital stock or other equity interests or voting power are, directly or indirectly, controlled,
owned or held by, or (ii) that is, at the time any determination is made, controlled (whether by voting power, Contract (as defined below)
or otherwise) by, in each case, the Company (either alone or through or together with one or more of its other Subsidiaries).

 

(b)               
Authorization, Enforcement, Compliance with Other Instruments. (i) The Company and each of its Subsidiaries party thereto
has the requisite corporate power and authority to enter into and perform its obligations under this Agreement and the Registration Rights
Agreement, (collectively with all other documents, certificates or instruments executed and delivered in connection with the transactions
contemplated hereby or thereby, the “Transaction Documents”) and to consummate the transactions
contemplated thereby, including to issue the Shares, in accordance with the terms hereof and thereof; (ii) the execution and delivery
by the Company and each of its Subsidiaries party thereto of each of the Transaction Documents and the consummation by it of the transactions
contemplated hereby and thereby, including, without limitation, the issuance of the Shares, have been duly authorized by the board of
directors of the Company the (“Board of Directors”) or other applicable governing body of the Company or such
Subsidiary, and no further action, proceeding, consent, waiver or authorization is required by or from the Company or any such Subsidiary,
its respective board of directors or other governing body or its respective stockholders or equity holders; (iii) this Agreement
and each of the other Transaction Documents have been duly executed and delivered by the Company; and (iv) this Agreement and the
other Transaction Documents constitute the valid and binding obligations of the Company enforceable against the Company and its Subsidiaries
party thereto in accordance with their terms, except as such enforceability may be limited by general principles of equity or applicable
bankruptcy, insolvency, reorganization, moratorium, liquidation or similar laws relating to, or affecting generally, the enforcement of
creditors’ rights and remedies and, with respect to any rights to indemnity or contribution contained in the Transaction Documents,
as such rights may be limited by state or federal laws or public policy underlying such laws.

 

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(c)               
Capitalization. As of the date hereof, the authorized capital stock of the Company consists of 300,000,000 shares of Common
Stock and 10,000,000 shares of preferred stock, par value $0.0001 per share (the “Preferred Stock”), and there
are 25,541,809 shares of Common Stock outstanding and no shares of Preferred Stock outstanding. All of the outstanding shares of Common
Stock and of the capital stock of each of the Company’s Subsidiaries have been duly authorized, validly issued and are fully paid
and non-assessable and free of preemptive or similar rights and other Liens. All of the issued and outstanding capital stock of each Subsidiary
of the Company are owned, directly or indirectly, by the Company, free and clear of any Liens. No shares of capital stock of the Company
or any of its Subsidiaries are subject to preemptive rights or any other similar rights or any Liens suffered or permitted by the Company.
Except as set forth in the SEC Reports there are no outstanding options, warrants, scrip, rights to subscribe to, calls or commitments
of any character whatsoever relating to, or securities or rights convertible, exercisable or exchangeable into, any shares of capital
stock of the Company or any of its Subsidiaries, or any Contracts by which the Company or any of its Subsidiaries is or may become bound
or pursuant to which the Company or any of its Subsidiaries is otherwise obligated to issue additional shares of capital stock of the
Company or any of its Subsidiaries. Except as set forth in the SEC Reports, there are no outstanding debt securities of the Company or
any of its Subsidiaries. Except as set forth in the SEC Reports, other than pursuant to the Registration Rights Agreement, there are no
agreements or arrangements under which the Company or any of its Subsidiaries is obligated to register the sale of any of their securities
under the Securities Act. Except as set forth in the SEC Reports, there are no securities or instruments of the Company or any of its
Subsidiaries containing anti-dilution or similar provisions, including the right to adjust the exercise, exchange or reset price under
such securities, that will be triggered by the issuance of the Shares as described in this Agreement. No co-sale right, right
of first refusal or other similar right will exist with respect to the Shares or the issuance and sale thereof. True and correct copies
of the Company’s Certificate of Incorporation, as in effect as of the Closing Date, and the Company’s Bylaws, as in effect
as of the Closing Date have heretofore been filed as part of the SEC Reports. Except for the interests in the Company’s Subsidiaries,
neither the Company nor any of its Subsidiaries owns any equity interest or other interest of any nature in, or any interest convertible,
exchangeable, or exercisable for, equity interests or other interests of any nature in any other person.

 

(d)               
Issuance of Shares. The Shares, when issued, sold and delivered in accordance with the terms and upon payment the consideration
set forth in this Agreement, will be duly and validly issued, fully paid and non-assessable, and free of preemptive or similar rights,
Taxes and other Liens with respect to the issuance thereof, and restrictions on transfer other than restrictions on transfer under the
Transaction Documents, applicable state and federal securities Laws and Liens created by or imposed by the Purchaser. Assuming the accuracy
of each of the representations and warranties of the Purchaser herein, the offer, issuance and sale by the Company of the Shares to the
Purchaser is exempt from registration under the Securities Act.

 

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(e)               
No Conflicts. The execution, delivery and performance of each of the Transaction Documents by the Company, and the consummation
by the Company of the transactions contemplated hereby and thereby, including issuance and sale of the Shares in accordance with
this Agreement, have not and will not (i) result in a violation of the Certificate of Incorporation or the Bylaws (or equivalent
constitutive document) of the Company or any of its Subsidiaries; (ii) violate or conflict with, or result in a breach of any provision
of, or constitute a default (or an event which with notice or lapse of time or both would become a default) under, or give to others any
rights of termination, amendment, acceleration or cancellation of, any Contract to which the Company or any Subsidiary is a party, except
for those which would not reasonably be expected to be material to the business of the Company and its Subsidiaries, taken as a whole,
or (iii) result in a violation of any Law applicable to the Company or any Subsidiary or by which any property or asset of the Company
or any Subsidiary is bound or affected, except for those which would not reasonably be expected to be material to the business of the
Company and its Subsidiaries, taken as a whole. Neither the Company nor any Subsidiary is in violation of or in default under, any provision
of its Certificate of Incorporation or Bylaws or any other constitutive documents. Neither the Company nor any Subsidiary is in violation
of any term of or in default under any Contract, judgment, decree or order or any Law applicable to the Company or any Subsidiary, which
violation or breach has been or would reasonably be expected to be material to the business of the Company and its Subsidiaries, taken
as a whole. Except as specifically contemplated by this Agreement and as required under the Securities Act and any applicable state securities
Laws, neither the Company nor any of its Subsidiaries is required to obtain any Authorization of, or provide any notice to or make any
filing or registration with, any Governmental Authority in order for it to execute, deliver or perform any of its obligations under or
contemplated by this Agreement or the other Transaction Documents in accordance with the terms hereof or thereof, other than (i) the filings
required pursuant to Section 5(i), (ii) the filing of the registration statement contemplated by the Registration Rights Agreement and
(iii) the filing of a Notice of Exempt Offering of Securities on Form D with the Securities and Exchange Commission (the “SEC”)
under Regulation D. Neither the execution and delivery by the Company of the Transaction Documents, nor the consummation by the Company
of the transactions contemplated hereby or thereby, will require any notice, consent or waiver under any Contract to which the Company
or any Subsidiary is a party or by which the Company or any Subsidiary is bound or to which any of their assets or businesses is subject,
except for any notice, consent or waiver the absence of which would not reasonably be expected, individually or in the aggregate, to be
material to the business of the Company and its Subsidiaries, taken as a whole.

 

(f)                
Absence of Litigation. There has not been any, action, suit, claim, inquiry, notice of violation, arbitration, petition,
charge, citation, summons, subpoena, proceeding (including any partial proceeding such as a deposition) or investigation of any nature,
civil, criminal, administrative, regulatory or otherwise, whether at law or in equity, before or by any Governmental Authority (an “Action”)
pending or threatened in writing or, to the knowledge of the Company, threatened orally, against or affecting the Company or any of its
Subsidiaries or any of their respective officers or directors or any of their respective assets or businesses, which has or would be reasonably
likely to (i) adversely affect the validity or enforceability of, or the authority or ability of the Company to perform its obligations
under, this Agreement or any of the other Transaction Documents or (ii) be material to the business of the Company and its Subsidiaries,
taken as a whole. For the purpose of this Agreement, the knowledge of the Company means the knowledge of the officers of the Company,
both actual or knowledge that they would have had upon reasonable inquiry of the personnel of the Company responsible for the applicable
subject matter.

 

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(g)               
Acknowledgment Regarding Purchaser’s Purchase of the Shares. The Company acknowledges and agrees that the Purchaser
is acting solely in the capacity of an arm’s length purchaser with respect to the Transaction Documents and the transactions contemplated
hereby and thereby. The Company further acknowledges that the Purchaser is not acting as a financial advisor or fiduciary of the Company
(or in any similar capacity) with respect to the Transaction Documents and the transactions contemplated thereby and any advice given
by the Purchaser or any of its representatives or agents in connection with the Transaction Documents and the transactions contemplated
thereby is merely incidental to the Purchasers’ purchase of the Shares.

 

(h)               
No General Solicitation. Neither the Company, nor any of its Affiliates, nor, to the knowledge of the Company, any person
acting on its or their behalf, has engaged in any form of general solicitation or general advertising (within the meaning of Regulation
D) in connection with the offer or sale of the Shares. “Affiliate” means, with respect to any person, any other
person that, directly or indirectly though one more intermediaries, controls, is controlled by or is under common control with such person
as such terms are used in and construed under Rule 144 under the Securities Act (“Rule 144”).

 

(i)                
No Integrated Offering. Neither the Company, nor any of its Affiliates, nor to the knowledge of the Company, any person
acting on its or their behalf has, directly or indirectly, made any offers or sales of any security or solicited any offers to buy any
security, under circumstances that would eliminate the availability of the exemption from registration under Rule 506(b) of Regulation
D or afforded by Section 4(a)(2) of the Securities Act in connection with the Offering of the Shares contemplated hereby or cause this
Offering of the Shares to be integrated with prior offerings by the Company for purposes of the Securities Act.

 

(j)                
Employee Relations. No labor dispute, work stoppage, request for representation, union organizing activity, or unfair labor
practice charges involving the employees of the Company or any of its Subsidiaries exists or is threatened in writing or, to the knowledge
of the Company, threatened orally. Neither Company nor any Subsidiary is party to any collective bargaining agreement. The Company’s
and/or its Subsidiaries’ employees are not members of any union, and the Company believes that its and its Subsidiaries’ relationship
with their respective employees is good.

 

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(k)               
Intellectual Property Rights. Except as set forth in the SEC Reports, the Company and each of its Subsidiaries exclusively
owns, possesses, or has valid and enforceable rights to use, license, and exploit all Intellectual Property used in, necessary or advisable
for the conduct of the Company’s and its Subsidiaries’ business as currently conducted, except for a failure to own, possess
or have such rights that would not reasonably be expected to result in a Material Adverse Effect. There are no unreleased liens or security
interests which have been filed, or which the Company has received notice of, against any of the Intellectual Property owned by the Company.
All Intellectual Property owned by the Company or its Subsidiaries, and all Contracts pursuant to which the Company or its Subsidiaries
license Intellectual Property, are valid and enforceable, and the Company and its Subsidiaries are in full compliance with all such Contracts
except as would not reasonably be expected to result in a Material Adverse Effect. Furthermore, except as has not been and would not reasonably
be expected to result in a Material Adverse Effect: (A) to the Company’s knowledge, there has been no infringement, misappropriation
or violation by third parties of any such Intellectual Property of the Company or its Subsidiaries; (B) there has been no Action pending
or threatened in writing (or to the Company’s knowledge, threatened orally) by others challenging the Company’s or any of
its Subsidiaries’ ownership of or any rights in or to any such Intellectual Property; (C) the Intellectual Property owned by
the Company and its Subsidiaries and, to the Company’s knowledge, the Intellectual Property licensed to the Company and its Subsidiaries,
has not been adjudged invalid or unenforceable, in whole or in part, and there has been no Action pending or threatened in writing (or
to the Company’s knowledge, threatened orally) by others challenging the validity, enforceability or scope of any such Intellectual
Property; (D) there has been no Action pending or threatened in writing (or to the Company’s knowledge, threatened orally)
by others that the Company or any of its Subsidiaries infringes, misappropriates or otherwise violates any Intellectual Property or other
proprietary rights of others, and neither the Company nor any of its Subsidiaries has received any written notice of such Action; and
(E) to the Company’s knowledge, no employee of the Company or any of its Subsidiaries has violated any term of any employment
Contract, patent disclosure agreement, invention assignment agreement, non-competition agreement, non-solicitation agreement,
nondisclosure agreement or any restrictive covenant to or with a former employer where the basis of such violation relates to such employee’s
employment with the Company or any of its Subsidiaries or actions undertaken by the employee while employed with the Company or any of
its Subsidiaries. The Company and its Subsidiaries have complied in all material respects with 37 C.F.R. §1.56. The consummation
of the transactions contemplated hereby or by the other Transaction Documents will not result in the loss or impairment of or payment
of any additional amounts with respect to, nor require the consent of any other person in respect of, the Company or any of its Subsidiaries’
right to own, use or hold for use any Intellectual Property as owned, used or held for use in the conduct of the Company’s and its
Subsidiaries’ business as currently conducted, except as would not reasonably be expected to be material to the business of the
Company and its Subsidiaries, taken as a whole. The rights of the Company and each of its Subsidiaries in their Intellectual Property
are valid, subsisting and enforceable, except as would not reasonably be expected to be material to the business of the Company and its
Subsidiaries, taken as a whole. The Company and each of its Subsidiaries has taken reasonable steps to maintain their Intellectual Property
and to protect and preserve the confidentiality of all of their Trade Secrets. To the Company’s knowledge, there has not been any
disclosure or access to any Trade Secrets of the Company and each of its Subsidiaries by any unauthorized person. The Company and each
of its Subsidiaries have taken and continue to take commercially reasonable measures, at least consistent with prevailing industry practice,
to ensure that all personal information in their possession, custody or control is protected against loss and against unauthorized, access,
use, modification, disclosure or other misuse. “Intellectual Property” shall mean any and all rights title and
interest in, arising out of, or associated with any intellectual or intangible property, whether protected, created or arising in any
jurisdiction throughout the world, including the following: (a) issued patents and patent applications (whether provisional or non-provisional),
including divisionals, continuations, continuations-in-part, substitutions, reissues, reexaminations, extensions, or restorations of any
of the foregoing, and other Governmental Authority issued indicia of invention ownership (including certificates of invention, petty patents,
and patent utility models) (“Patents”); (b) trademarks, service marks, brands, certification marks, logos, trade
dress, slogans, trade names, and other similar indicia of source or origin, together with the goodwill connected with the use of and symbolized
by, and all registrations, applications for registration, and renewals of, any of the foregoing (“Trademarks”);
(c) copyrights and works of authorship, whether or not copyrightable, and all registrations, applications for registration, and renewals
of any of the foregoing (“Copyrights”); (d) internet domain names and social media account or user names (including
 “handles”), whether or not Trademarks, all associated web addresses, URLs, websites and web pages, social media
sites and pages, and all content and data thereon or relating thereto, whether or not Copyrights; (e) mask works, and all registrations,
applications for registration, and renewals thereof; (f) industrial designs, and all Patents, registrations, applications for registration,
and renewals thereof; (g) trade secrets, know-how, inventions (whether or not patentable), discoveries, improvements, technology, business
and technical information, databases, data compilations and collections, tools, methods, processes, techniques, and other confidential
and proprietary information and all rights therein (“Trade Secrets”); (h) computer programs, operating systems,
applications, firmware and other code, including all source code, object code, application programming interfaces, data files, databases,
protocols, specifications, and other documentation thereof; (i) rights of publicity; and (j) all other intellectual or industrial property
and proprietary rights.

 

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(l)                
Environmental Laws.

 

(i)            Except as would not reasonably be expected to be material
to the business of the Company and its Subsidiaries, taken as a whole: (x) the Company and each Subsidiary is in compliance and has complied
with all applicable Environmental Laws (as defined below); (y) the Company or its applicable Subsidiary is in possession of all Authorizations
required pursuant to Environmental Laws to conduct their respective businesses as currently conducted and (z) the Company or its applicable
Subsidiary is in material compliance with all terms and conditions of such Authorizations. There is no Action pending or threatened in
writing (or to the Company’s knowledge, threatened orally) relating to any violation or noncompliance with any Environmental Law
involving the Company or any Subsidiary. For purposes of this Agreement, “Environmental Law” means any national,
state, provincial or local Law, statute, rule or regulation or the common law relating to the environment or occupational health and safety,
including without limitation any statute, regulation, administrative decision or order pertaining to (A) treatment, storage, disposal,
generation and transportation of Hazardous Substances; (B) air, water and noise pollution; (C) groundwater and soil contamination;
(D) the release or threatened release into the environment of industrial, toxic or hazardous materials or substances, or solid or
hazardous waste, including without limitation emissions, discharges, injections, spills, escapes or dumping of pollutants, contaminants
or chemicals; (E) the protection of wild life, marine life and wetlands, including without limitation all endangered and threatened
species; (F) storage tanks, vessels, containers, abandoned or discarded barrels, and other closed receptacles; (G) health and
safety of employees and other persons; and (H) manufacturing, processing, using, distributing, treating, storing, disposing, transporting
or handling of Hazardous Substances. As used above, the terms “release” and “environment” shall have the meaning
set forth in the Comprehensive Environmental Response, Compensation and Liability Act of 1980, as amended.

 

(ii)            None of the Company or any of its Subsidiaries has any liability
or obligation under any Environmental Law with respect to any release, spill, emission, leaking, pumping, pouring, emptying, leaching,
escaping, dumping, injection, deposit, discharge or disposing of any Hazardous Substance in, onto or through the environment, except as
would not reasonably be expected to have a Material Adverse Effect. “Hazardous Substances” means all materials,
wastes, or substances defined by, or regulated under, any Environmental Laws, including as a hazardous waste, hazardous material, hazardous
substance, extremely hazardous waste, restricted hazardous waste, contaminant, pollutant, toxic waste, or toxic substance, and specifically
including petroleum and petroleum products, asbestos, radon, lead, toxic mold, radioactive materials, and polychlorinated biphenyls.

 

    	 	8	 

     

    

 

(m)             
Authorizations; Regulatory Compliance. The Company and each of its Subsidiaries holds, and is operating in compliance with,
all authorizations, licenses, permits, approvals, clearances, registrations, exemptions, consents, certificates, waivers, filings, qualifications
and orders of each applicable entity or body exercising executive, legislative, judicial, regulatory or administrative functions of or
pertaining to United States federal, state or local government or foreign, or other governmental, including any department, commission,
board, agency, bureau, official or other regulatory, administrative or judicial or arbitral authority thereto (each a “Governmental
Authority”) and supplements and amendments thereto (collectively, “Authorizations”) required for
the conduct of its business as currently conducted or that are otherwise material to the business of the Company and its Subsidiaries,
in all applicable jurisdictions, except as would not reasonably be expected to be material to the business of the Company and its Subsidiaries,
taken as a whole. All Authorizations held by the Company or its Subsidiaries are valid and in full force and effect. Neither the Company
nor any of its Subsidiaries is in material violation of any terms of any such Authorizations; and neither the Company nor any of its Subsidiaries
has received written notice from any Governmental Authority of any revocation or modification of any such Authorization, or written notice
(or to the Company’s knowledge, oral notice) that such revocation or modification is being considered, except to the extent that
any such revocation or modification would not be reasonably expected to be material to the business of the Company and its Subsidiaries,
taken as a whole. The Company and each of its Subsidiaries is in compliance, and has since the Lookback Date been in compliance, with
all applicable federal, state, local and foreign Laws, including such Laws applicable to the manufacture, distribution, import and export
of regulated products and component parts, except as would not reasonably be expected to be material to the business of the Company and
its Subsidiaries, taken as a whole. Neither the Company nor any of its Subsidiaries has received written notice (or to the Company’s
knowledge, oral notice) of any ongoing claim, action, suit, proceeding, hearing, enforcement, investigation, arbitration or other action
from any Governmental Authority or third party alleging that any product operation or activity is in material violation of any Laws or
any Authorizations. The Company and each of its Subsidiaries has filed, obtained, maintained or submitted all material reports, documents,
forms, notices, applications, records, claims, submissions and supplements or amendments thereto as required by any Laws or any Authorizations
and all such reports, documents, forms, notices, applications, records, claims, submissions and supplements or amendments, to the Company’s
knowledge, were complete, correct and not misleading on the date filed in all material respects (or were corrected or supplemented by
a subsequent submission). Neither the Company nor any of its Subsidiaries has, either voluntarily or involuntarily, initiated, conducted,
or issued or caused to be initiated, conducted or issued, any other notice or action relating to any alleged product defect or violation
and, to the Company’s knowledge, no third party has initiated or conducted any such notice or action relating to any of the Company’s
products in development. Neither the Company nor any of its Subsidiaries is a party to any corporate integrity agreement, deferred prosecution
agreement, monitoring agreement, consent decree, settlement order, or similar agreements, or has any reporting obligations pursuant to
any such agreement, plan or correction or other remedial measure entered into with any Governmental Authority.

 

    	 	9	 

     

    

 

(n)               
Title. Neither the Company nor any of its Subsidiaries owns any real property. Except as set forth in the SEC Reports, each
of the Company and its Subsidiaries has good and marketable title to all of its personal property and other tangible assets (i) purportedly
owned or used by them as reflected in the SEC Reports, or (ii) necessary for the conduct of their business as currently conducted, free
and clear of any legal or equitable, specific or floating, lien (statutory or otherwise), restriction, mortgage, deed of trust, pledge,
lien, security interest, restrictive covenant, or other adverse right, charge, claim or encumbrance of any kind or nature whatsoever (collectively,
 “Liens”), except for Liens which would not reasonably be expected to have a Material Adverse Effect. Each of
the Company and its Subsidiaries is in compliance with such leases and holds a valid leasehold interest free of any Liens, except for
such Liens which would not reasonably be expected to have a Material Adverse Effect.

 

(o)               
Tax Status. The Company and each Subsidiary has filed (taking into account any valid extensions) all federal, state, local
and foreign income and all other material returns, declarations, reports, elections, designations, or information returns or statements
made to a Governmental Authority relating to Taxes, including any schedules or attachments thereto and any amendments thereof (collectively,
 “Tax Returns”) required to be made or filed by it or with respect to it by any jurisdiction to which it is subject.
Such Tax Returns accurately reflect, in all material respects, the Tax liabilities of the Company and its Subsidiaries (other than Taxes
not yet due and payable). The Company and each Subsidiary has timely paid all income Taxes and all other material Taxes and other material
governmental assessments and material charges, shown or determined to be due on such returns, reports and declarations, except those being
contested in good faith and for which the Company and its Subsidiaries have adequately reserved and accrued for in accordance with GAAP.
The Company has reserved and accrued on its books provisions in accordance with GAAP amounts that are reasonably adequate for the payment
of all material taxes for periods subsequent to the periods to which such returns, reports or declarations apply. There are no unpaid
Taxes in any material amount claimed to be due from the Company or any Subsidiary by the taxing authority of any jurisdiction. There are
no pending or threatened in writing (or to the Company’s knowledge, threatened orally) Actions by the taxing authority of any jurisdiction
against the Company or any of its Subsidiaries. Neither the Company nor any of its Subsidiaries is a party to, or otherwise bound by,
any Tax indemnity, Tax sharing or Tax allocation agreement (but not including any agreement whose primary subject matter is not Taxes)
(a “Tax Agreement”). The Company is not a “United States real property holding corporation” within the
meaning of Section 897(c) of the Internal Revenue Code of 1986, as amended (the “Code”). For purposes of this
Agreement, “Tax” or “Taxes” means (i) any and all U.S. federal, state, local, or non-U.S.
taxes, assessment, levy or other charges, including net or gross income, gross receipts, net proceeds, estimated, sales, use, ad valorem,
value added, franchise, license, withholding, payroll, employment, excise, property (including both real and personal), unclaimed property
remittance/escheat, deed, stamp, alternative or add-on minimum, occupation, severance, unemployment, social security, workers’ compensation,
capital, premium, windfall profit, environmental, custom duties, fees, transfer and registration taxes, and any governmental charges in
the nature of a tax imposed by a Governmental Authority, (ii) any liability for the payment of any amounts of any of the foregoing types
as a result of being a member of an affiliated, consolidated, combined or unitary group, or being a party to any agreement or arrangement
whereby liability for payment of such amounts was determined or taken into account with reference to the liability of any other person
and (iii) any liability for the payment of any amounts as a result of being a party to any Tax Agreement.

 

    	 	10	 

     

    

 

(p)               
Certain Transactions. Except as set forth in the SEC Reports, none of the direct or indirect equity holders, shareholders,
controlling persons, partners, managers, members, officers, directors, employees, general or limited partners or assignees (each, a “Related
Party”) of the Company or any Subsidiary is presently, or has since January 1, 2020 been, a party to any Contract or transaction
with the Company or any Subsidiary (other than for services as employees, officers and directors), including any Contract providing for
the furnishing of services to or by, providing for rental of real or personal property to or from, or otherwise requiring payments to
or from any officer, director or such employee or, to the knowledge of the Company, any corporation, partnership, trust or other entity
in which any officer, director, or any such employee has a substantial interest or is an officer, director, trustee or partner. All transactions
that would be required to be disclosed by the Company pursuant to Item 404 of Regulation S-K promulgated under the Securities Act
are disclosed in the SEC Reports in accordance with Item 404 of Regulation S-K.

 

(q)               
Rights of First Refusal. The Company is not obligated to offer the securities offered hereunder on a right of first refusal
basis or otherwise to any third parties including, but not limited to, current or former stockholders of the Company, underwriters, brokers,
agents or other third parties.

 

(r)                
Insurance. The Company and its Subsidiaries have insurance policies of the type and in amounts customarily carried by organizations
conducting businesses or owning assets similar to those of the Company and its Subsidiaries, and in any event maintain insurance policies
in amounts as required by applicable Law or any Contract to which the Company or its Subsidiaries is a party or to which any of its assets
or businesses is subject. All such insurance policies are in full force and effect and binding and enforceable in accordance with their
terms, and all premiums due and payable thereon have been timely paid in full. Neither the Company nor any of its Subsidiaries is in default
with respect to its obligations under any such insurance policy, nor has there been any failure to give any notice or present any claim
under any such insurance policy in due and timely fashion except as would not, individually or in the aggregate, reasonably be expected
to be material to the business of the Company and its Subsidiaries, taken as a whole. There is no material claim pending under any such
policy as to which coverage has been questioned, denied or disputed by the underwriter of such policy and there has been no notice of
cancellation of nonrenewal of any such insurance policy received by the Company or any of its Subsidiaries. No limits on any insurance
policy of the Company or any of its Subsidiaries have been exhausted, materially eroded or materially reduced.

 

(s)                
SEC Reports. The Company has timely filed or furnished, as applicable, all registration statements, reports, proxy statements,
schedules, forms, statements, certifications and other documents (including exhibits and all other information incorporated by reference
therein) required to be filed or furnished by the Company under the Securities Act or the Securities and Exchange Act of 1934, as amended
(the “Exchange Act”) (together, the “SEC Reports”). There are no outstanding or unresolved
comments in comment letters received from the SEC staff with respect to the SEC Reports. None of the SEC Reports is the subject of an
ongoing SEC review. There are no SEC inquiries or investigations, other governmental inquiries or investigations or internal investigations
pending or threatened in writing (or, to the Company’s knowledge, threatened orally), in each case regarding any accounting practice
of the Company.

 

    	 	11	 

     

    

 

(t)                
Financial Statements.

 

(i)    
The audited consolidated financial statements of the Company as of and for the fiscal years ended December 31, 2020 and December
31, 2019 and the unaudited consolidated condensed financial statements for the nine months ended September 30, 2021 and September 30,
2020, all included in the SEC Reports comply in all material respects with GAAP and the rules and regulations of the SEC with respect
thereto as in effect at the time of filing and (the financial statements referenced in the foregoing clause (i), the “Financial
Statements”). The Financial Statements have been prepared in accordance with GAAP applied on a consistent basis during the
periods involved and include all adjustments (consisting only of normal recurring accruals) that are necessary for a fair presentation
of the consolidated financial condition of the entities or business to which they relate as of the date thereof, and fairly present in
all material respects the financial position of the Company and its Subsidiaries taken as a whole as of and for the dates thereof and
the results of operations and cash flows for the periods then ended.

 

(ii)  
The Company (A) maintains a standard system of accounting established and administered in accordance with GAAP and (B) has established
and maintains a system of internal controls over financial reporting designed to provide reasonable assurance regarding the reliability
of the financial reporting and the preparation of the Financial Statements for external purposes in accordance with GAAP. There (x) are
no significant deficiencies or weaknesses in any system of internal accounting controls used by each of the Company’s Subsidiaries,
(y) has not since the Lookback Date been any fraud or other unlawful act on the part of any of management or other employees of the Company
and each of its Subsidiaries who have a role in the preparation of Financial Statements or the internal accounting controls used by the
Company and each of its Subsidiaries related to such preparation or controls and (z) has not since the Lookback Date been any claim or
allegation regarding any of the foregoing.

 

(iii)
Neither the Company nor any of its Subsidiaries has any liabilities (whether accrued, absolute, contingent or otherwise) other than (A)
liabilities disclosed on the audited balance sheet (including the notes thereto) or the interim balance sheet (including the notes thereto)
and (B) liabilities that have been incurred since the date of the latest balance sheet of the Company included in the Financial Statements
in the ordinary course of business, which liabilities, individually or in the aggregate, are not material to the business of the Company
and its Subsidiaries (taken as a whole).

 

(iv) 
To the knowledge of the Company, BDO LLP (the “Auditor”) is an independent registered public accounting
firm with respect to the Company as required by the Exchange Act and the rules and regulations promulgated thereunder and the rules and
regulations of the Public Company Accounting Oversight Board. The Auditor has not, during the periods covered by the Financial Statements
provided to the Company any non-audit services, as such term is used in Section 10A(g) of the Exchange Act.

 

(u)               
Material Changes.  Except for the transactions contemplated hereby, since the date of the latest balance sheet
of the Company and the latest balance sheet of the Company included in SEC Reports, (i) there have been no events, occurrences or
developments that have had or would reasonably be expected to have a Material Adverse Effect with respect to the Company or SmartKem,
(ii) there have not been any changes in the assets, financial condition, business or operations of the Company from that reflected
in the financial statements contained in SEC Reports except changes in the ordinary course of business which have not been, either individually
or in the aggregate, materially adverse to the business, properties, financial condition, results of operations or future prospects of
the Company, (iii) none of the Company or any of their respective Subsidiaries has altered its method of accounting or the manner in which
it keeps its accounting books and records, and (iv) none of the Company or any of their respective Subsidiaries has declared or made
any dividend or distribution of cash or other property to its stockholders or equity holders or purchased, redeemed or made any agreements
to purchase or redeem any shares of its capital stock (other than in connection with repurchases of unvested stock issued to employees
of the Company). The Company and its Subsidiaries, individually and on a consolidated basis, are not as of the date hereof, and after
giving effect to the transactions contemplated hereby to occur at the Closing, will not be Insolvent (as defined below). “Insolvent”
means, with respect to the Company, on a consolidated basis with its Subsidiaries, (i) the present fair saleable value of the Company’s
and its Subsidiaries’ assets is less than the amount required to pay the Company’s and its Subsidiaries’ total indebtedness,
(ii) the Company and its Subsidiaries are unable to pay their debts and liabilities, subordinated, contingent or otherwise, as such debts
and liabilities become absolute and matured or (iii) the Company and its Subsidiaries intend to incur or believe that they will incur
debts that would be beyond their ability to pay as such debts mature.

 

    	 	12	 

     

    

 

(v)               
Disclosure Controls. The Company has established and maintains disclosure controls and procedures (as defined in Rules 13a-14 and 15d-15 under
the Exchange Act) and such controls and procedures are effective in ensuring that material information relating to the Company, including
its Subsidiaries, is made known to the principal executive officer and the principal financial officer.

 

(w)             
Sarbanes-Oxley. The Company is, and has been, to the extent applicable, in compliance in all material respects with all
of the provisions of the Sarbanes-Oxley Act of 2002 which are applicable to it.

 

(x)               
Off-Balance Sheet Arrangements. There is no transaction, arrangement, or other relationship between the Company or
any Subsidiary and an unconsolidated or other off-balance sheet entity that is required to be disclosed by the Company in the
SEC Reports and is not so disclosed.

 

(y)               
Foreign Corrupt Practices. Neither the Company and its Subsidiaries, nor any of their respective directors, managers, officers,
agents or employees or other person acting on behalf of the Company or its Subsidiaries, has: (i) directly or indirectly, used any
funds for unlawful contributions, gifts, entertainment or other unlawful expenses related to foreign or domestic political activity, (ii) made
any unlawful payment or offered anything of value to foreign or domestic government officials or employees or to any foreign or domestic
political parties or campaigns from corporate funds, (iii) failed to disclose fully any contribution made by the Company or any of
its Subsidiaries (or, to the Company’s knowledge, made by any person acting on their behalf) which is in violation of Law or (iv)
violated any applicable anti-terrorism Law or regulation, nor have any of them otherwise taken any action which would reasonably cause
the Company or any of its Subsidiaries to be in violation of the Foreign Corrupt Practices Act of 1977, as amended, the UK Bribery Act
of 2010, as amended, or any applicable Law of similar effect.

 

(z)               
Office of Foreign Assets Control. Neither the Company nor any Subsidiary nor, to the Company’s knowledge, any director,
manager, officer, agent, employee or Affiliate of the Company or any Subsidiary is, or is acting under the direction of, on behalf of
or for the benefit of a person that is, or is owned or controlled by a person that is, currently subject to any U.S. sanctions administered
by the Office of Foreign Assets Control of the U.S. Treasury Department.

 

    	 	13	 

     

    

 

(aa)            
Money Laundering. The operations of the Company and its Subsidiaries are and have been conducted at all times in compliance
with applicable financial record-keeping and reporting requirements of the Currency and Foreign Transactions Reporting Act of 1970, as
amended, and other applicable money laundering Laws and applicable rules and regulations thereunder (collectively, the “Money
Laundering Laws”), and no Action by or before any Governmental Authority involving the Company or any Subsidiary with respect
to the Money Laundering Laws is pending or threatened in writing (or to the Company’s knowledge, threatened orally).

 

(bb)           
Regulation M Compliance. The Company has not, and to its knowledge no one acting on its behalf has, (i) taken, directly
or indirectly, any action designed to cause or to result in the stabilization or manipulation of the price of any security of the Company
to facilitate the sale or resale of any of the Shares, (ii) sold, bid for, purchased, or paid any compensation for soliciting purchases
of, any of the Shares, or (iii) paid or agreed to pay to any person any compensation for soliciting another to purchase any other securities
of the Company.

 

(cc)            
Privacy and Data Security.

 

(i)            “Business Privacy and Data Security Policies”
means all of the Company’s or one of its Subsidiaries’ present, internal or public-facing policies, notices, and statements
concerning the privacy, security, or Processing of Personal Information in the conduct of the Business. “Personal Information”
means any information that identifies or, alone or in combination with any other information, could reasonably be used to identify, locate,
or contact a natural person, including name, street address, telephone number, email address, identification number issued by a Governmental
Authority, credit card number, bank information, customer or account number, online identifier, device identifier, IP address, browsing
history, search history, or other website, application, or online activity or usage data, location data, biometric data, medical or health
information, or any other information that is considered “personally identifiable information,” “personal information,”
or “personal data” under applicable Law, and all data associated with any of the foregoing that are or could reasonably be
used to develop a profile or record of the activities of a natural person across multiple websites or online services, to predict or infer
the preferences, interests, or other characteristics of a natural person, or to target advertisements or other content to a natural person.
 “Privacy Laws” means all applicable Laws, orders, writs, judgments, injunctions, decrees, stipulations, determinations
or awards entered by or with any Governmental Authority, and binding guidance issued by any Governmental Authority concerning the privacy,
security, or Processing of Personal Information (including Laws of jurisdictions where Personal Information was collected), including,
as applicable, data breach notification Laws, consumer protection Laws, Laws concerning requirements for website and mobile application
privacy policies and practices, Social Security number protection Laws, data security Laws, and Laws concerning email, text message, or
telephone communications. Without limiting the foregoing, Privacy Laws include the Health Insurance Portability and Accountability Act
of 1996, as amended and supplemented by the Health Information Technology for Economic and Clinical Health Act of the American Recovery
and Reinvestment Act of 2009, the General Data Protection Regulation (Regulation (EU) 2016/679), and all other similar international,
federal, state, provincial, and local Laws. “Processing” means any operation performed on Personal Information,
including the collection, creation, receipt, access, use, handling, compilation, analysis, monitoring, maintenance, storage, transmission,
transfer, protection, disclosure, destruction, or disposal of Personal Information.

 

    	 	14	 

     

    

 

(ii)           
The Company and each of its Subsidiaries, and, to the Company’s knowledge, all vendors, processors, or other third parties acting
for or on behalf of the Company or any of its Subsidiaries in connection with the Processing of Personal Information or that otherwise
have been authorized to have access to Personal Information in the possession or control of the Company or any of its Subsidiaries, comply
and at all times since the Lookback Date have complied, with all of the following in the conduct of its business as currently conducted:
(A) Privacy Laws; (B) rules of self-regulatory organizations; (C) industry standards, guidelines, and best practices; (D) the Business
Privacy and Data Security Policies; and (E) all obligations or restrictions concerning the privacy, security, or Processing of Personal
Information under any Contract to which the Company or any of its Subsidiaries is a party or otherwise bound as of the date hereof, in
each case, except for violations that, individually or in the aggregate, have not been and would not reasonably be expected to be material
to the business of the Company and its Subsidiaries, taken as a whole.

 

(iii)           
The execution, delivery and performance of this Agreement and the consummation of the transactions contemplated hereby, does not or will
not: (A) conflict with or result in a violation or breach of any Privacy Laws or Business Privacy and Data Security Policies (as currently
existing or as existing at any time during which any Personal Information was collected or Processed by or for the Company or any of
its Subsidiaries in the conduct of its business as now being conducted); or (B) require the consent of or notice to any person concerning
such person’s Personal Information, in each case, except as has not been and would not reasonably be expected to have a Material
Adverse Effect.

 

(iv)            (A) no Personal Information in the possession or control
of the Company or any of its Subsidiaries, or to the Company’s knowledge, held or Processed by any vendor, processor, or other third
party for or on behalf of the Company or any of its Subsidiaries, in the conduct of its business has been subject to any data or security
breach or unauthorized access, disclosure, use, loss, denial or loss of use, alteration, destruction, compromise, or Processing (a “Security
Incident”), and (B) neither the Company nor any of its Subsidiaries has notified and, to the Company’s knowledge,
there have been no facts or circumstances that would require the Company or any of its Subsidiaries to notify, any Governmental Authority
or other person of any Security Incident in the conduct of its business, in each case, except as has not been and would not reasonably
be expected to have a Material Adverse Effect.

 

(v)            neither the Company nor any of its Subsidiaries has received
any notice, request, claim, complaint, correspondence, or other communication in writing (or to the Company’s knowledge, orally)
from any Governmental Authority or other person, and to the Company’s knowledge there has not been any audit, investigation, enforcement
action (including any fines or other sanctions), or other Action relating to, any actual, alleged, or suspected Security Incident or violation
of any Privacy Law involving Personal Information in the possession or control of the Company or any of its Subsidiaries, or held or Processed
by any vendor, processor, or other third party for or on behalf of the Company or any of its Subsidiaries, in the conduct of its business,
in each case, except as has not been and would not reasonably be expected to be material to the business of the Company and its Subsidiaries,
taken as a whole.

 

    	 	15	 

     

    

 

(vi)           
In the conduct of its business, the Company and each of its Subsidiaries has at all times implemented and maintained, and required all
vendors, processors, and other third parties that Process any Personal Information for or on behalf of the Company or any of its Subsidiaries
to implement and maintain, all security measures, plans, procedures, controls, and programs, including written information security programs,
to (A) identify and address internal and external risks to the privacy and security of Personal Information in their possession or control;
(B) implement, monitor, and improve adequate and effective administrative, technical, and physical safeguards to protect such Personal
Information and the operation, integrity, and security of its software, systems, applications, and websites involved in the Processing
of Personal Information; and (C) provide notification in compliance with applicable Privacy Laws in the case of any Security Incident,
in each case, except as has not been and would not reasonably be expected to be material to the business of the Company and its Subsidiaries,
taken as a whole.

 

(dd)           
Disclosure Materials. The SEC Reports, at the time filed or furnished, were true and correct in all material respects and
did not or will not contain an untrue statement of a material fact or omit to state a material fact required to be stated therein or necessary
to make the statements therein, in the light of the circumstances under which they were made, not misleading.

 

(ee)            
Investment Company. The Company is not required to be registered as, and is not an Affiliate of, and immediately following
the Closing will not be required to register as, an “investment company” within the meaning of the Investment Company Act
of 1940, as amended.

 

(ff)              
Reliance. The Company acknowledges that the Purchaser is relying on the representations and warranties (as modified by the
SEC Reports (excluding any disclosures (whether contained under the heading “Risk Factors,” in any “forward-looking
statements” disclaimer or in any other section) to the extent they are cautionary, predictive or forward-looking in nature) made
by the Company hereunder and that such representations and warranties (as modified by the SEC Reports (excluding any disclosures
(whether contained under the heading “Risk Factors,” in any “forward-looking statements” disclaimer or in any
other section) to the extent they are cautionary, predictive or forward-looking in nature) are a material inducement to the Purchaser
purchasing the Shares. The Company further acknowledges that without such representations and warranties of the Company made hereunder,
the Purchaser would not enter into this Agreement with the Company.

 

(gg)           
Bad Actor Disqualification. No “bad actor” disqualifying event described in Rule 506(d)(1)(i)-(viii) of the
Securities Act (a “Disqualification Event”) is applicable to the Company or, to the Company’s knowledge,
any Company Covered Person, except for a Disqualification Event as to which Rule 506(d)(2)(ii–iv) or (d)(3), is applicable. “Company
Covered Person” means, with respect to the Company as an “issuer” for purposes of Rule 506 promulgated under
the Securities Act, any person listed in the first paragraph of Rule 506(d)(1). The Company represents that it has exercised reasonable
care to determine the accuracy of the representation made by the Company in this paragraph.

 

    	 	16	 

     

    

 

(hh)           
Anti-Dilution. There are no securities or instruments issued by or to which the Company is a party as of the date hereof
or as of the Closing containing anti-dilution or similar provisions that will be triggered by the issuance of the Shares in connection
with the Offering or pursuant to any other Subscription Agreement entered into in connection with the Offering.

 

(ii)              
Leased Real Property. There are no pending or, to the knowledge of the Company, any threatened condemnation proceedings,
lawsuits or other Actions relating to any real property leased by the Company or any of its Subsidiaries or any of the buildings, structures
and facilities located thereon (the “Leased Real Property”) or other matters affecting adversely the current
use, occupancy or value thereof. The Company and its applicable Subsidiaries enjoy quiet possession under all leases for each parcel of
Leased Real Property (each, a “Lease”) and no Leased Real Property under any such Lease is subject to any Lien,
easement, right-of-way, building or use restriction, exception, variance, reservation or limitation, as might, in any material respect,
interfere with or impair the present and continued use thereof by the Company or its Subsidiaries in the usual and normal conduct of the
business of the Company and its Subsidiaries.

 

(jj)              
Material Contracts.

 

(i)                
“Material Contracts” means any written or oral agreement, contract, commitment, arrangement, subcontract,
license, sublicense, lease, sublease, sales order, purchase order, indenture, mortgage, note, bond, letter of credit, warrant, instrument,
obligation, or understanding (collectively, including all amendments, supplements and modifications thereto, “Contracts”)
to which the Company or any of its Subsidiaries is a party or by which any of their respective assets or businesses are bound:

 

(A) 
that is a “material contract” (as such term is defined in Item 601(b)(10) of Regulation S-K promulgated under the Securities
Act);

 

(B) 
that is a joint venture, alliance, partnership or similar agreement that is material to the operation of the Company and its Subsidiaries,
taken as a whole;

 

(C) 
that provides for payments to the Company or any of its Subsidiaries or includes future payment obligations of the Company or its
Subsidiaries outside of the ordinary course of business, in each case, in excess of $100,000 annually;

 

(D) 
that creates a Lien on any material asset of the Company or any of its Subsidiaries;

 

(E)  
that evidences indebtedness of the Company or any of its Subsidiaries;

 

(F)  
that contains an exclusivity clause that restricts the Company or any of its Subsidiaries or a covenant not to compete in any line
of business with any person in any geographical area that restricts the Company or any of its Subsidiaries or that otherwise restricts
the Company or any of its Subsidiaries from freely providing products or services to any customer or potential customer, or that restricts
the right of the Company or any of its Subsidiaries to sell to or purchase from any other person;

 

    	 	17	 

     

    

 

(G) 
that relates to the acquisition or disposition of any business (whether by merger, sale of stock or assets or otherwise) at any
time since the Lookback Date other than those related to the Company’s efforts to seek the acquisition of an operating company prior
to the acquisition of SmartKem;

 

(H) 
that is with any Related Party of the Company or any of its Subsidiaries;

 

(I)    
that grants to the counterparty a right of first refusal, first offer or first negotiation outside of the ordinary course of business
of the Company;

 

(J)    
that grants the other party or any third party “most favored nation” status or any similar rights;

 

(K) 
that is a Lease;

 

(L)  
other than in the ordinary course of business, (i) that grants any person a right to use Intellectual Property of the Company or
any of its Subsidiaries or (ii) that grants the Company or any of its Subsidiaries to use the Intellectual Property of another person;

 

(M)
that provides for indemnification to or from any person with respect to liabilities relating to the business of the Company or its Subsidiaries
or any former businesses of the Company or its Subsidiaries or any predecessor thereof; or

 

(N) 
that is otherwise material to the business of the Company and its Subsidiaries, taken as a whole.

 

(ii)  
Each Material Contract is the legal, valid and binding obligation of the Company or one of its Subsidiaries that is a party thereto,
and is enforceable against the Company or one of its Subsidiaries, as applicable, and, to the knowledge of the Company, the counterparties,
in accordance with its terms, other than, in all cases, Material Contracts that have expired, been terminated or superseded in accordance
with their terms following the date hereof. Neither the Company or any of its Subsidiaries, nor to the knowledge of the Company, any counterparty,
is in violation, breach or default under any such Contract or has improperly terminated, revoked or accelerated any Material Contract
and no event or condition exists or has occurred which, with the giving of notice or the lapse of time or both, would, under any Material
Contract, (A) constitute a breach or default by the Company or any of its Subsidiaries, or to the knowledge of the Company, a counterparty,
(B) give to the counterparty any rights of termination, acceleration or cancellation of, (C) result in any obligation imposed on the Company
or any of its Subsidiaries thereunder or a loss of a benefit in favor of the Company or any of its Subsidiaries thereunder, (D) allow
the imposition of any fees or penalties on the Company or any of its Subsidiaries thereunder, require the offering or making of any payment
or redemption by the Company or any of its Subsidiaries thereunder or (E) give rise to any increased, guaranteed, accelerated or additional
rights or entitlements to the counterparty thereunder, in each case, except for such breaches, defaults and events which would not reasonably
be expected to have a Material Adverse Effect. None of the Company or any of its Subsidiaries has received any written notice of the intention
of any person to terminate, fail to renew or materially and adversely modify any Material Contract.

 

    	 	18	 

     

    

 

(kk)           
Employee Benefits.

 

(i)    
 “Benefit Plan” means any plan, program, arrangement or agreement that is a pension, profit-sharing,
savings, retirement, employment, consulting, severance pay, termination, executive compensation, incentive compensation, deferred compensation,
bonus, stock purchase, stock option, phantom stock or other equity-based compensation, change-in-control, retention, salary continuation,
vacation, sick leave, disability, death benefit, group insurance, hospitalization, medical, dental, life (including all individual life
insurance policies as to which the Company is the owner, the beneficiary, or both), Code Section 125 “cafeteria” or “flexible”
benefit, employee loan, educational assistance or fringe benefit plan, program, arrangement or agreement, whether written or oral, including,
without limitation, any (A) “employee benefit plan” within the meaning of Section 3(3) of the Employee Retirement Income Security
Act of 1974, as amended, and the rules and regulations promulgated thereunder (“ERISA”) or (B) other employee
benefit plans, agreements, programs, policies, arrangements or payroll practices, whether or not subject to ERISA (including any funding
mechanism therefor now in effect or required in the future as a result of the transaction contemplated by this Agreement or otherwise),
which the Company or any of its Subsidiaries sponsors or maintains for the benefit of its current or former officer, director, employee,
leased employee, consultant or agent (or their respective beneficiaries), or with respect to which the Company or any of its Subsidiaries
has, or could reasonably be expected to have, any direct or indirect present or future liability.

 

(ii)  
Each Benefit Plan has been established, maintained and operated in all respects in accordance with its terms and in compliance
with all applicable provisions of applicable Laws, including Section 409A of the Code and the regulations and other guidance issued thereunder,
in each case, except as has not been and would not reasonably be expected to have, a Material Adverse Effect. There are no investigations
by any Governmental Authority, termination proceedings or other claims (except routine claims for benefits payable under the Benefit Plans)
or Actions pending in writing (or to the Company’s knowledge, orally) against any Benefit Plan or asserting any rights to or claims
for benefits under any Benefit Plan that would reasonably be expected to give rise to any material liability. No non-exempt “prohibited
transaction” (within the meaning of Section 406 of ERISA and Section 4975 of the Code) has occurred or is reasonably expected to
occur with respect to any Benefit Plan. No Benefit Plan is (A) subject to Section 412 of the Code, Title IV of ERISA or Section 302 of
ERISA (including a “multiemployer” plan within the meaning of Section 3(37) of ERISA), (B) a “multiple employer plan”
as defined in Section 413(c) of the Code, or (C) a “multiple employer welfare arrangement” within the meaning of Section 3(40)
of ERISA. No Benefit Plan is subject to the Laws of any jurisdiction other than the United States.

 

(iii)
Neither the execution and delivery of this Agreement nor the consummation of the transactions contemplated hereby shall, in connection
with any other event(s), (i) result in any payment or benefit becoming due to any current or former employee, contractor or director of
the Company or its Subsidiaries or under any Benefit Plan, (ii) increase any amount of compensation or benefits otherwise payable to any
current or former employee, contractor or director of the Company or its Subsidiaries or under any Benefit Plan, (iii) result in the acceleration
of the time of payment, funding or vesting of any benefits to any current or former employee, contractor or director of the Company or
its Subsidiaries or under any Benefit Plan, (iv) limit the right to merge, amend or terminate any Benefit Plan (except any limitations
imposed by applicable Law, if any), or (v) give rise to any “excess parachute payment” as defined in Section 280G(b)(l) of
the Code, any excise tax owing under Section 4999 of the Code or any other amount that would not be deductible under Section 280G of the
Code.

 

    	 	19	 

     

    

 

3.      
Representations, Warranties and Agreements of the Purchaser. Each Purchaser, severally and not jointly, represents
and warrants to, and agrees with, the Company the following:

 

(a)               
The Purchaser has the knowledge and experience in financial and business matters necessary to evaluate the merits and risks of
its prospective investment in the Company, and has carefully reviewed and understands the risks of, and other considerations relating
to, the purchase of Shares and the tax consequences of the investment. The Purchaser has adequate means of providing for its current and
anticipated financial needs and contingencies and is able to bear the economic risks of the investment for an indefinite period of time
and has no need for liquidity of the investment in the Shares. The Purchaser can afford the loss of his, her or its entire investment.

 

(b)               
The Purchaser is acquiring the Shares, for investment for his, her or its own account and not with the view to, or for resale in
connection with, any distribution thereof. The Purchaser understands and acknowledges that the Offering and sale of the Shares have not
been registered under the Securities Act or any state securities Laws, by reason of a specific exemption from the registration provisions
of the Securities Act and applicable state securities Laws, which depends upon, among other things, the bona fide nature of the investment
intent as expressed herein. The Purchaser further represents that he, she or it does not have any contract, undertaking, agreement or
arrangement with any person to sell, transfer or grant participation to any third person with respect to the Shares, other than with respect
to an Affiliate of the Purchaser. The Purchaser understands and acknowledges that the Offering of the Shares will not be registered under
the Securities Act nor under the state securities laws on the ground that the sale of such sales to the Purchaser as provided for in this
Agreement and the issuance of Shares hereunder is exempt from the registration requirements of the Securities Act and any applicable state
securities laws. The Purchaser is an “accredited investor” as defined in Rule 501 of Regulation D as promulgated by the SEC
under the Securities Act for the reason(s) specified on the Accredited Investor Certification attached hereto as completed by the Purchaser.
The Purchaser resides in the jurisdiction set forth on the Purchaser’s Omnibus Signature Page affixed hereto. If the Purchaser is,
with respect to the Company, (i) a predecessor of the Company; (ii) an affiliated issuer; (iii) a director, executive officer, other officer
participating in the offering, general partner or managing member of the Company; (iii) any beneficial owner of 20% or more of the Company's
outstanding voting equity securities, calculated on the basis of voting power; (iv) any promoter connected with the Company in any capacity
at the time of such sale; (v) any investment manager of the Company if the Company is a pooled investment fund; (vi) any person that has
been or will be paid (directly or indirectly) remuneration for solicitation of purchasers in connection with the Offering; (vii) any general
partner or managing member of any such investment manager or solicitor; or (viii) any director, executive officer or other officer participating
in the offering of any such investment manager or solicitor or general partner or managing member of such investment manager or solicitor
(each such category, a “Covered Person”), the Purchaser has not taken any of the actions set forth in, and is
not subject to, the disqualification provisions of Rule 506(d)(1) of the Securities Act.

 

    	 	20	 

     

    

 

(c)               
The Purchaser (i) if a natural person, represents that he or she is the greater of (A) 21 years of age or (B) the age
of legal majority in his or her jurisdiction of residence, and has full power and authority to execute and deliver this Agreement and
all other related agreements or certificates and to carry out the provisions hereof and thereof; (ii) if a corporation, partnership,
limited liability company, association, joint stock company, trust, unincorporated organization or other entity, represents that such
entity is duly organized, validly existing and in good standing under the Laws of the state or jurisdiction of its organization, the consummation
of the transactions contemplated hereby is authorized by, and will not result in a violation of applicable Law or its charter or other
organizational documents, such entity has full power and authority to execute and deliver this Agreement and all other related agreements
or certificates and to carry out the provisions hereof and thereof and to purchase and hold the Shares, the execution and delivery of
this Agreement has been duly authorized by all necessary action, this Agreement has been duly executed and delivered on behalf of such
entity and is a legal, valid and binding obligation of such entity; or (iii) if executing this Agreement in a representative or fiduciary
capacity, represents that he, she or it has full power and authority to execute and deliver this Agreement in such capacity and on behalf
of the subscribing individual, ward, partnership, trust, estate, corporation, or limited liability company or partnership, or other entity
for whom the Purchaser is executing this Agreement, and such individual, partnership, ward, trust, estate, corporation, or limited liability
company or partnership, or other entity has full right and power to perform pursuant to this Agreement and make an investment in the Company,
and represents that this Agreement constitutes a legal, valid and binding obligation of such entity. The execution and delivery of this
Agreement will not violate or be in conflict with any order, judgment, injunction, agreement or controlling document to which the Purchaser
is a party or by which it is bound, except for any violation or conflict that, individually or in the aggregate, has not had and would
not reasonably be expected to have a material adverse effect on the ability of the Purchaser to perform its obligations under this Agreement
and the other Transaction Documents or to consummate any transactions contemplated hereby or thereby.

 

(d)               
The Purchaser understands that the Shares are being offered and sold to him, her or it in reliance on specific exemptions from
the registration requirements of United States federal and state securities Laws and that the Company is relying in part upon the truth
and accuracy of, and the Purchaser’s compliance with, the representations, warranties, agreements, acknowledgments and understandings
of the Purchaser set forth herein in order to determine the availability of such exemptions and the eligibility of the Purchaser to acquire
such securities. The Purchaser further acknowledges and understands that the Company is relying on the representations and warranties
made by the Purchaser hereunder and that such representations and warranties are a material inducement to the Company to sell the Shares
to the Purchaser. The Purchaser further acknowledges that without such representations and warranties of the Purchaser made hereunder,
the Company would not enter into this Agreement with the Purchaser.

 

(e)               
The Purchaser understands that, other than as expressly provided in the Registration Rights Agreement, the Company does not currently
intend to register the Shares under the Securities Act at any time in the future; and the undersigned will not immediately be entitled
to the benefits of Rule 144 with respect to the Shares. The Purchaser understands that no public market exists for the Company’s
Common Stock and that there can be no assurance that any public market for the Common Stock will exist or continue to exist. The Company’s
Common Stock is not approved for quotation on OTC Markets or any other quotation system or listed on any exchange.

 

(f)                
The Purchaser has received, reviewed and understood the information about the Company set forth in the SEC Reports and has had
an opportunity to discuss the Company’s business, management and financial affairs with the Company’s management. The Purchaser
understands that such discussions were intended to describe the aspects of the Company’s business and prospects and the Offering
which the Company believes to be material, but were not necessarily a thorough or exhaustive description and except as expressly set forth
in this Agreement (as modified by the SEC Reports (excluding any disclosures contained under the heading “Risk Factors,” any
disclosures of risks included in any “forward looking statements” or disclosures that are cautionary, predictive or forward-looking
in nature)), the Company makes no representation or warranty with respect to the completeness of such information and makes no representation
or warranty of any kind with respect to any information provided by any entity other than the Company. Some of such information may include
projections as to the future performance of the Company, which projections may not be realized, may be based on assumptions which may
not be correct and may be subject to numerous factors beyond the Company’s control. The Purchaser acknowledges that he, she or it
is not relying upon any person or entity, other than the Company and its officers and directors, in making its investment or decision
to invest in the Company.

 

    	 	21	 

     

    

 

(g)               
The Purchaser acknowledges that the Company is not acting as a financial advisor or fiduciary of the Purchaser (or in any similar
capacity) with respect to the Transaction Documents and the transactions contemplated hereby and thereby, and no investment advice has
been given by the Company or any of its respective representatives or agents in connection with the Transaction Documents and the transactions
contemplated hereby and thereby.

 

(h)               
All actions on the part of the Purchaser, and its officers, directors and partners, if applicable, necessary for the authorization,
execution and delivery of this Agreement and the Registration Rights Agreement and the performance of all obligations of the Purchaser
hereunder and thereunder have been taken, and this Agreement and the Registration Rights Agreement constitute valid and legally binding
obligations of the Purchaser, enforceable against the Purchaser in accordance with their respective terms, except as such enforceability
may be limited by general principles of equity or applicable bankruptcy, insolvency, reorganization, moratorium, liquidation or similar
Laws relating to, or affecting generally, the enforcement of creditors’ rights and remedies.

 

(i)                
The Purchaser represents that neither it nor, to its knowledge, any person or entity controlling, controlled by or under common
control with it, nor any person having a beneficial interest in the Purchaser, nor any person on whose behalf the Purchaser is acting:
(i) is a person listed in the Annex to Executive Order No. 13224 (2001) issued by the President of the United States (Executive
Order Blocking Property and Prohibiting Transactions with Persons Who Commit, Threaten to Commit, or Support Terrorism); (ii) is named
on the List of Specially Designated Nationals and Blocked Persons maintained by the U.S. Office of Foreign Assets Control; (iii) is
a non-U.S. shell bank or is providing banking services indirectly to a non-U.S. shell bank; (iv) is a senior non-U.S. political
figure or an immediate family member or close associate of such figure; or (v) is otherwise prohibited from investing in the Company
pursuant to applicable U.S. anti-money laundering, anti-terrorist and asset control Laws, regulations, rules or orders (categories (i) through
(v), each a “Prohibited Purchaser”). The Purchaser (A) agrees to provide the Company, promptly upon request,
all information that the Company reasonably deems necessary or appropriate to comply with applicable U.S. anti-money laundering, anti-terrorist
and asset control Laws, regulations, rules and orders and (B) consents to the disclosure to U.S. regulators and law enforcement authorities
by the Company and its Affiliates and agents of such information about the Purchaser as the Company reasonably deems necessary or appropriate
to comply with applicable U.S. anti-money laundering, anti-terrorist and asset control Laws, regulations, rules and orders. If the Purchaser
is a financial institution that is subject to the USA Patriot Act, the Purchaser represents that it has met all of its obligations under
the USA Patriot Act. The Purchaser acknowledges that if, following its investment in the Company, the Company reasonably believes that
the Purchaser is a Prohibited Purchaser or is otherwise engaged in suspicious activity or refuses to promptly provide information that
the Company requests, the Company has the right or may be obligated to prohibit additional investments, segregate the assets constituting
the investment in accordance with applicable regulations or immediately require the Purchaser to transfer the Shares. The Purchaser further
acknowledges that neither the Purchaser nor any of the Purchaser’s Affiliates or agents will have any claim against the Company
for any form of damages as a result of any of the foregoing actions.

 

    	 	22	 

     

    

 

(j)                
If the Purchaser is an Affiliate of a non-U.S. banking institution (a “Foreign Bank”), or if
the Purchaser receives deposits from, makes payments on behalf of, or handles other financial transactions related to a Foreign Bank,
the Purchaser represents and warrants to the Company that: (1) the Foreign Bank has a fixed address, other than solely an electronic
address, in a country in which the Foreign Bank is authorized to conduct banking activities; (2) the Foreign Bank maintains operating
records related to its banking activities; (3) the Foreign Bank is subject to inspection by the banking authority that licensed the
Foreign Bank to conduct banking activities; and (4) the Foreign Bank does not provide banking services to any other Foreign Bank
that does not have a physical presence in any country and that is not a regulated Affiliate.

 

(k)               
The Purchaser or its duly authorized representative realizes that because of the inherently speculative nature of businesses of
the kind conducted and contemplated by the Company, the Company’s financial results may be expected to fluctuate from month to month
and from period to period and will, generally, involve a high degree of financial and market risk that could result in substantial or,
at times, even total losses for investors in securities of the Company. The Purchaser has considered the risk factors in the SEC Reports
before deciding to invest in the Shares.

 

(l)                
The Purchaser is not subscribing for Shares as a result of or subsequent to any advertisement, article, notice or other communication,
published in any newspaper, magazine or similar media or broadcast over television, radio, or the internet, or presented at any seminar
or meeting, or any solicitation of a subscription by a person not previously known to the Purchaser in connection with investments in
securities generally.

 

(m)             
The Purchaser acknowledges that no U.S. federal or state agency or any other government or governmental agency has passed upon
the Shares or made any finding or determination as to the fairness, suitability or wisdom of any investments therein.

 

(n)               
Other than consummating the transactions contemplated hereunder, the Purchaser has not directly or indirectly, nor has any individual
or entity acting on behalf of or pursuant to any understanding with the Purchaser, executed any purchases or sales, including Short Sales
(as defined below), of the securities of the Company during the period commencing at the time the Purchaser was first contacted by the
Company or any other individual or entity representing the Company regarding the transactions contemplated hereunder. Notwithstanding
the foregoing, in the case of a Purchaser being a multi-managed investment vehicle whereby separate portfolio managers manage separate
portions of the Purchaser’s assets and the portfolio managers do not communicate or share information with, and have no direct knowledge
of the investment decisions made by, the portfolio managers managing other portions of the Purchaser’s assets, the representation
set forth above shall only apply with respect to the portion of assets managed by the portfolio manager that made the investment decision
to purchase the Shares covered by this Agreement. Notwithstanding the foregoing, for avoidance of doubt, nothing contained herein shall
constitute a representation or warranty, or preclude any actions, with respect to the identification of the availability of, or securing
of, available shares to borrow in order to effect Short Sales or similar transactions in the future. For purposes of this Agreement, “Short
Sales” means all “short sales” as defined in Rule 200 of Regulation SHO under the Exchange Act (but shall not
be deemed to include the location and/or reservation of borrowable shares of Common Stock).

 

    	 	23	 

     

    

 

(o)               
The Purchaser is aware that the anti-manipulation rules of Regulation M under the Exchange Act may apply to sales of the Shares,
if any, and other activities with respect to the Shares by the Purchaser, and will comply with such anti-manipulation rules of Regulation
M.

 

(p)               
All of the information concerning the Purchaser set forth herein, and any other information furnished by the Purchaser in writing
to the Company for use in connection with the transactions contemplated by this Agreement, is true, correct and complete in all material
respects as of the date of this Agreement, and, if there should be any material change in such information prior to the Purchaser’s
purchase of the Shares, the Purchaser will promptly furnish revised or corrected information to the Company.

 

(q)               
The Purchaser has reviewed with its own tax advisors the U.S. federal, state, local and foreign tax consequences of this investment
and the transactions contemplated by the Transaction Documents. With respect to such matters, the Purchaser relies solely on such advisors
and not on any statements or representations of the Company or any of its agents, written or oral. The Purchaser understands that it (and
not the Company) shall be responsible for its own tax liability that may arise as a result of this investment or the transactions contemplated
by the Transaction Documents.

 

(r)                
If the Purchaser is not a United States person (as defined by Section 7701(a)(30) of the Code), the Purchaser hereby represents
that it has satisfied itself as to the observance in all material respects of the Laws of its jurisdiction in connection with any invitation
to subscribe for the Shares or any use of this Agreement, including (a) the legal requirements within its jurisdiction for the purchase
of the Shares; (b) any foreign exchange restrictions applicable to such purchase; (c) any governmental or other consents that
may need to be obtained; and (d) the income tax and other tax consequences, if any, that may be relevant to the purchase, holding,
redemption, sale or transfer of the Shares. The Purchaser’s subscription and payment for and continued beneficial ownership of the
Shares will not violate any applicable securities or other Laws of the Purchaser’s jurisdiction.

 

(s)                
The Purchaser represents that it is not a “foreign person” for purposes of Section 721 of the Defense Production Act
of 1950 (as amended) or the rules or regulations promulgated thereunder (including 31 C.F.R. Part 800 and 31 C.F.R. part 801); provided,
however, that if the Purchaser is a “foreign person” for such purposes, it agrees that it will not (i) obtain any control
rights over the Company, including the ability to determine, direct, or decide important matters affecting the Company; (ii) have access
to any material nonpublic technical information in the possession of the company; (iii) obtain membership or observer rights on the Board
of Directors or the right to nominate an individual to a position on the Board of Directors; or (iv) have any involvement, other than
through voting of shares, in substantive decision making of the Company regarding the use, development, acquisition or release of the
Company’s technology.

 

    	 	24	 

     

    

 

(t)                
If the Purchaser is a Covered Person, neither the Purchaser nor, to the Purchaser’s knowledge, any of its directors, executive
officers, other officers that may serve as a director or officer of any company in which it invests, general partners or managing members
is subject to any Disqualification Events, except for Disqualification Events covered by Rule 506(d)(2)(ii) or (iii) under the Securities
Act, and disclosed reasonably in advance of the applicable Closing in writing in reasonable detail to the Company.

 

(u)               
The Purchaser understands that there are substantial restrictions on the transferability of the Shares, if any, and that the certificates
or book-entry positions representing the Shares, shall bear a restrictive legend in substantially the following form (and a stop-transfer
order may be placed against transfer of such certificates or other instruments):

 

THE SECURITIES REPRESENTED BY THIS 
BOOK-ENTRY POSITION HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, AND THE RULES AND REGULATIONS PROMULGATED THEREUNDER
(THE “SECURITIES ACT”), OR ANY STATE SECURITIES LAWS, AND NEITHER SUCH SECURITIES NOR ANY INTEREST THEREIN MAY
BE OFFERED, SOLD, PLEDGED, ASSIGNED OR OTHERWISE TRANSFERRED UNLESS (1) A REGISTRATION STATEMENT WITH RESPECT THERETO IS EFFECTIVE
UNDER THE SECURITIES ACT AND ANY APPLICABLE STATE SECURITIES LAWS, OR (2) AN EXEMPTION FROM SUCH REGISTRATION EXISTS AND THE COMPANY
RECEIVES AN OPINION OF COUNSEL, WHICH COUNSEL AND OPINION ARE REASONABLY SATISFACTORY TO THE COMPANY, THAT SUCH SECURITIES MAY BE OFFERED,
SOLD, PLEDGED, ASSIGNED OR TRANSFERRED IN THE MANNER CONTEMPLATED WITHOUT AN EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES ACT
OR APPLICABLE STATE SECURITIES LAWS OR (3) SOLD PURSUANT TO RULE 144 UNDER THE SECURITIES ACT.

 

In addition, if the Purchaser is an Affiliate
of the Company, certificates or book-entry positions evidencing the Shares issued to the Purchaser may bear a customary “Affiliates”
legend.

 

Any fees (with respect to the Company's transfer
agent (the “Transfer Agent”), counsel or otherwise) associated with the removal of such legend(s) shall be borne
by the Company.

 

    	 	25	 

     

    

 

The
Company shall be obligated to promptly reissue unlegended certificates upon the request of any holder thereof  at such time as the
securities evidenced by such certificates or book entry positions are sold pursuant to (x)Rule 144 or another applicable exemption from
the registration requirements of the Securities Act has been satisfied or (y)  an effective  registration statement and
in accordance with the plan of distribution set forth in such registration statement ,provided that the Company’s counsel and its
transfer agent have received an opinion (in the case of (x)) and a certificate(in the case of (y)) in such form as the Company’s
counsel reasonably requests that such securities have been disposed of pursuant to clause (x) or (y) above, as applicable. Under the foregoing
circumstances, the Company shall cause its transfer agent to issue unlegended shares, within one (1) Trading Day after the transfer
agent’s receipt of such opinion or certification, via DWAC or as otherwise requested by the holder.

 

(v)            
If the Purchaser is an individual, then the Purchaser resides in the state or province identified in the address of the Purchaser
set forth on such Purchaser’s Omnibus Signature Page to this Agreement; if the Purchaser is a partnership, corporation, limited
liability company or other entity, then the office or offices of the Purchaser in which its principal place of business is identified
in the address or addresses of the Purchaser set forth on such Purchaser’s Omnibus Signature Page to this Agreement.

 

(w)             
The Purchaser understands that the Company has been a “shell company” as defined in Rule 12b-2 under the
Exchange Act. Pursuant to Rule 144(i), securities issued by a current or former shell company (that is, the Shares) that otherwise meet
the holding period and other requirements of Rule 144 nevertheless cannot be sold in reliance on Rule 144 until one year after
the Company filed current “Form 10 information“ (as defined in Rule 144(i)) with the SEC reflecting that it is no longer a
shell company, and provided that at the time of a proposed sale pursuant to Rule 144, the Company is subject to the reporting requirements
of Section 13 or 15(d) of the Exchange Act and has filed all reports and other materials required to be filed by Section 13
or 15(d) of the Exchange Act, as applicable, during the preceding 12 months (or for such shorter period that the issuer was required to
file such reports and materials), other than Form 8-K reports. As a result, the restrictive legends on certificates
or book-entry positions for the Shares, if any, cannot be removed except in connection with an actual sale (i) meeting the foregoing requirements
or (ii) pursuant to an effective registration statement.

 

		4.	Indemnification.

 

(a)               
In addition to the indemnity provided to the Purchaser in the applicable Registration Rights Agreement, the Company agrees to indemnify
and hold harmless the Purchaser and its Affiliates, and its and their respective directors, officers, stockholders, equityholders, members,
managers, partners, employees, attorneys, consultants, representatives and agents (and any other persons with a functionally equivalent
role of a person holding such titles notwithstanding a lack of such title or any other title), each person who controls the Purchaser
(within the meaning of Section 15 of the Securities Act and Section 20 of the Exchange Act), and the directors, officers, stockholders,
equityholders, members, managers, partners, employees, attorneys, consultants, representatives and agents (and any other persons with
a functionally equivalent role of a person holding such titles notwithstanding a lack of such title or any other title) of such controlling
person (collectively, the “Purchaser Indemnitees”), from and against all losses, liabilities, claims, damages,
costs, fees, charges, Taxes, judgements, fines, penalties and expenses whatsoever (including, but not limited to, amounts paid in settlement
and any and all out-of-pocket expenses, including attorneys’ fees and expenses, incurred in investigating, preparing or defending
against any litigation commenced or threatened) (collectively, “Indemnified Liabilities”) arising out of or
relating to: (i) the inaccuracy, violation or breach of any of the Company’s representations or warranties made in Section 2 of
this Agreement; (ii) any breach or failure to perform by the Company of any of its covenants and obligations contained herein or (iii)
any Action brought or made against such Purchaser Indemnitee by a third party (including for these purposes a derivative action brought
on behalf of the Company) and arising out of, relating to or resulting from (A) the execution, delivery, performance or enforcement of
the Transaction Documents or the transactions contemplated hereby or thereby, including the issuance of the Shares or (B) the status of
the Purchaser as an investor in the Company pursuant to the transactions contemplated hereby or by the other Transaction Documents. To
the extent that the foregoing undertaking by the Company may be unenforceable for any reason, the Company shall make the maximum contribution
to the payment and satisfaction of each of the Indemnified Liabilities that is permissible under applicable Law. The liability of the
Company under this paragraph shall not exceed the total Purchase Price paid by the Purchaser hereunder, except in the case of fraud.

 

    	 	26	 

     

    

 

(b)               
The Company shall have the right to control the investigation and defense of any Action for which a Purchaser Indemnitee may be
entitled to indemnification hereunder with counsel reasonably satisfactory to such Purchaser Indemnitee, at the sole cost and expense
of the Company, upon written notice to the applicable Purchaser Indemnitee; provided, that (i) such notice contains confirmation
that the Company has agreed to indemnify the Purchaser Indemnitee (subject to the limitations on indemnification set forth herein) for
the Indemnified Liabilities arising out of, relating to or resulting from such Action and (ii) the Company shall not be entitled to assume
or control the investigation and defense, if (A) such claim seeks non-monetary, equitable or injunctive relief or alleges any violation
of criminal Law or (B) the Indemnitor is also a party and the Indemnitee determines in good faith after consultation with counsel that
there may be one or more legal defenses available to such Indemnitee that are different or additional to those available to the Indemnitor.
If the Company assumes the investigation and defense of such Action in accordance herewith, the Purchaser Indemnitee may retain separate
co-counsel at its sole cost and expense and participate in the investigation and defense of such Action.

 

(c)               
Notwithstanding anything to the contrary herein, without the prior written consent of the Purchaser Indemnitee, the Company shall
not, and shall not cause or permit any of its Subsidiaries or its or their respective Related Parties to, negotiate, consent to or enter
into any settlement, or consent to the entry of any judgment, with respect to any Action for which such Purchaser Indemnitee may be entitled
to indemnification hereunder, unless such settlement (i) includes an unconditional release of such Purchaser Indemnitee from all liability
arising out of such proceeding, (ii) does not require any admission of wrongdoing by any Purchaser Indemnitee, and (iii) does not obligate
or require any Purchaser Indemnitee to take, or refrain from taking, any action.

 

(d)               
The Purchaser acknowledges on behalf of itself and each Purchaser Indemnitee that, other than (i) for Actions seeking specific
performance of the obligations under this Agreement; or (ii) in the case of a breach or violation of this Agreement by the Company which
has resulted from either (A) intentional fraud or (B) a deliberate act or failure to act with actual knowledge that the act
or failure to act constituted or would result in a breach or violation, in each case, the sole and exclusive remedy of the Purchaser and
the Purchaser Indemnitees with respect to any and all claims relating to this Agreement shall be pursuant to the indemnification provisions
(including the limitations thereof) set forth in this Section 4.

 

		5.	Miscellaneous.

 

(a)               
Modification. This Agreement shall not be amended, modified or waived except by an instrument in writing signed
by the Company and the holders of at least a majority of the Shares; provided that this Agreement may not be amended and the observance
of any term hereof may not be waived with respect to any Purchaser without the written consent of such Purchaser if such amendment or
waiver on its face materially and adversely affects the rights of such Purchaser under this Agreement in a manner that is different than
the other Purchasers. Any amendment, modification or waiver effected in accordance with this Section 5(a) shall be binding upon the Purchaser
and each transferee of the Shares each future holder of all such Shares and the Company, its successors and assigns.

 

    	 	27	 

     

    

 

(b)              
Notices. Any notice, consents, waivers or other communication required or permitted to be given hereunder shall
be in writing and will be deemed to have been delivered: (i) upon receipt, when personally delivered; (ii) upon receipt when
sent by certified mail, return receipt requested, postage prepaid; (iii) upon receipt, when sent by facsimile (provided confirmation
of transmission is mechanically or electronically generated and kept on file by the sending party); (iv) when sent, if by e-mail
(provided that such sent e-mail is kept on file (whether electronically or otherwise) by the sending party and the sending party
does not receive an automatically generated message from the recipient’s e- mail server that such e-mail could
not be delivered to such recipient); or (v) one (1) Business Day after deposit with a nationally recognized overnight courier service
with next day delivery specified, in each case, properly addressed to the party to receive the same. The addresses, facsimile numbers
and email addresses for such communications shall be:

 

		(i)	if to the Company, at

 

SmartKem, Inc. 

Manchester Technology Center, Hexagon
Tower 

Delaunays Road, Blackley 

Manchester 

M9 8GQ U.K. 

Attention: Robert Bahns 

Email: r.bahns@smartkem.com

 

with
copies (which shall not constitute notice) to:

 

Lowenstein Sandler LLP 

1251 Avenue of the Americas 

New York, NY 10020 

Attention: Jack Hogoboom 

Email: jhogoboom@lowenstein.com

 

or

 

		(ii)	if to a Purchaser, at the address of such Purchaser set forth on its Omnibus Signature Page hereto

 

(or, in either case, to such other address as
the party shall have furnished in writing in accordance with the provisions of this Section).

 

(d)               
Assignability. This Agreement and the rights, interests and obligations hereunder are not transferable or assignable
by the Purchaser, other than an assignment of the rights, interests and obligations hereunder in connection with any transfer of the Shares
by a Purchaser to a Permitted Assignee (as such term is defined in the Registration Rights Agreement). For the avoidance of doubt, nothing
in this Section 5(d) is intended to, or shall have the effect of, restricting or otherwise impairing any transfer of the Shares by the
Purchaser.

 

    	 	28	 

     

    

 

 

 

(e)               
Applicable Law. This Agreement and the other Transaction Documents and the transactions contemplated hereby
and thereby shall be governed by and construed in accordance with the Laws of the State of New York, without reference to the principles
thereof relating to the conflict of Laws. Any litigation based hereon, or arising out of, under or in connection with, this Agreement
or any other Transaction Document or the transactions contemplated hereby or thereby shall be brought and maintained exclusively in the
United States District Court for the Southern District of New York or the Supreme Court of the State of New York for New York County,
New York. Each party irrevocably consents to the service of process of any of the aforementioned courts in any such suit, action or proceeding
by the mailing of copies thereof by registered or certified mail, postage prepaid, return receipt requested, to such party's address set
forth in Section 5(i)(b), such service to become effective ten (10) days after such mailing.

 

(f)                
WAIVER OF JURY TRIAL.   EACH PARTY HERETO HEREBY IRREVOCABLY WAIVES ALL RIGHT TO TRIAL BY JURY IN ANY ACTION
OR COUNTERCLAIM (WHETHER BASED ON CONTRACT, TORT OR OTHERWISE) ARISING OUT OF OR RELATING TO THIS AGREEMENT, ANY OTHER TRANSACTION DOCUMENT,
THE TRANSACTIONS CONTEMPLATED HEREBY OR THEREBY OR THE ACTIONS OF SUCH PARTY IN THE NEGOTIATION, ADMINISTRATION, PERFORMANCE AND ENFORCEMENT
HEREOF.

 

(g)               
Form D; Blue Sky Qualification. The Company agrees to timely file a Form D with respect to the Shares and to provide a copy
thereof, promptly upon request of the Purchaser. The Company shall take such action as the Company shall reasonably determine is necessary
in order to obtain an exemption for, or to qualify the Shares for, sale to the Purchaser at such Closing under applicable securities or
 “Blue Sky” laws of the states of the United States, and shall provide evidence of such actions promptly upon request of the
Purchaser.

 

(h)               
Use of Pronouns. All pronouns and any variations thereof used herein shall be deemed to refer to the masculine,
feminine, neuter, singular or plural as the identity of the person or persons referred to may require.

 

(i)                
Securities Law Disclosure; Publicity.  The Company shall not publicly disclose the name of the Purchaser or
an Affiliate of the Purchaser, or include the name of the Purchaser or an Affiliate of the Purchaser in any press release or filing with
the SEC (other than the Registration Statement) or any regulatory agency or principal trading market, without the prior written consent
of the Purchaser, except (i) as required by federal securities Law in connection with (A) any registration statement contemplated
by the Registration Rights Agreement and (B) the filing of final Transaction Documents with the SEC or (ii) to the extent such
disclosure is required by applicable Law, request of the staff of the SEC or of any regulatory agency or principal trading market regulations,
in which case the Company shall provide the Purchaser with prior written notice of such disclosure permitted under this sub-clause (ii).
Each Purchaser, severally and not jointly, covenants that until such time as the transactions contemplated by this Agreement are publicly
disclosed by the Company as described in this Section 5(i), such Purchaser will maintain the confidentiality of all disclosures made to
it in connection with such transactions (including the existence and terms of such transactions), except to the extent such disclosure
(x) is made to the other Purchasers in connection with the transactions contemplated hereby or (y) is required by applicable Law. In addition,
each Purchaser acknowledges that it is aware that United States securities laws may restrict persons who have material,
non-public information about a company from purchasing or selling any securities of such company while in possession of such information.
The provisions of this Section 5(i) are in addition to and not in replacement of any other confidentiality agreement, if any, between
the Company and the Purchaser.

 

    	 	29	 

     

    

 

(j)                
Non-Public Information.  The Company shall not and shall cause each of its officers, directors, employees,
agents and other representatives, not to, provide the Purchaser with any material, non-public information regarding the Company
without the express prior written consent of the Purchaser.

 

(k)               
Entire Agreement. This Agreement, together with the Registration Rights Agreement and each other Transaction Document, and
all exhibits, schedules and attachments hereto and thereto, including any confidentiality agreement between the Purchaser and the Company,
constitute the entire agreement between the Purchaser and the Company with respect to the Offering and supersede all prior oral or written
agreements and understandings, if any, relating to the subject matter hereof.

 

(l)                
Share Certificates. If the Shares are certificated and any certificate or instrument evidencing any such securities is mutilated,
lost, stolen or destroyed, the Company shall issue or cause to be issued in exchange and substitution for and upon cancellation thereof,
or in lieu of and substitution therefor, a new certificate or instrument, but only upon receipt of evidence reasonably satisfactory to
the Company and the Company’s transfer agent of such loss, theft or destruction and the execution by the holder thereof of a customary
lost certificate affidavit of that fact and an agreement to indemnify and hold harmless the Company and its transfer agent for any losses
in connection therewith or, if required by such transfer agent, a bond in such form and amount as is required by the transfer agent. The
applicants for a new certificate or instrument under such circumstances shall also pay any reasonable third-party costs associated with
the issuance of such replacement securities. If a replacement certificate or instrument evidencing any such securities is requested due
to a mutilation thereof, the Company may require delivery of such mutilated certificate or instrument as a condition precedent to any
issuance of a replacement.

 

(m)             
Expenses. Each of the parties hereto shall pay its own fees and expenses (including the fees of any attorneys, accountants,
appraisers or others engaged by such party) in connection with this Agreement and the transactions contemplated hereby, whether or not
the transactions contemplated hereby are consummated. Without limiting the foregoing, the Company shall pay all Transfer Agent fees, stamp
taxes and other Taxes and duties levied in connection with the sale and issuance of the Offering, and the Company shall file all necessary
Tax Returns and other documentation with respect to such fees, Taxes and duties, and the Company shall pay all fees and expenses of its
counsel in connection with any opinion to the Transfer Agent for the removal of any legend on the Shares.

 

(n)               
Counterparts. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original but
all of which together shall constitute one and the same instrument. The exchange of copies of this Agreement and of Omnibus Signature
Pages that contain copies of an executed Omnibus Signature Page such as in .pdf format shall constitute effective execution and delivery
of this Agreement as to the parties and may be used in lieu of the original Agreement for all purposes. Signatures of the parties transmitted
by facsimile or by e-mail of a document in .pdf format shall be deemed to be their original signatures for all purposes.

 

    	 	30	 

     

    

 

(o)               
Severability. Each provision of this Agreement shall be considered separable and, if for any reason any provision or provisions
hereof are determined to be invalid or contrary to applicable Law, such invalid or contrary provision shall be replaced with a valid provision
that as closely as possible reflects the parties’ intent with respect thereto, and invalidity or illegality shall not impair the
operation of or affect the remaining portions of this Agreement.

 

(p)               
Headings. Paragraph titles are for descriptive purposes only and shall not control or alter the meaning of this Agreement
as set forth in the text.

 

(q)               
Additional Information; Further Assurances. The Purchaser hereby agrees to furnish the Company such other information as
the Company may reasonably request prior to the applicable Closing with respect to its subscription hereunder. Each party hereto shall
do and perform, or cause to be done and performed, all such further acts and things, and shall execute and deliver all such other agreements,
certificates, instruments and documents, as the other party hereto may reasonably request in order to effect the transactions contemplated
hereby and to accomplish the purposes of this Agreement and the consummation of the transactions contemplated hereby.

 

(r)                
Survival. The representation and warranties of the party shall survive the execution and delivery of this Agreement for
a period of one (1) year from the Closing Date and in each case, shall in no way be affected by any investigation or knowledge of the
subject matter thereof made by or on behalf of the Purchaser or the Company. The covenants and agreements contained in this Agreement
(including the covenants and agreements set forth in Section 4 hereof) shall survive the Closing and delivery of the Shares in accordance
with their terms or, if no term is specified, such covenants and agreements shall survive indefinitely. Notwithstanding anything herein
to the contrary, in no event shall the Purchaser have any liability to the Company or to any other person in connection with the Offering
other than pursuant to this Agreement.

 

(s)                
Omnibus Signature Page. This Agreement is intended to be read and construed in conjunction with the Registration Rights
Agreement. Accordingly, pursuant to the terms and conditions of this Agreement and the Registration Rights Agreement, it is hereby agreed
that the execution by the Purchaser of this Agreement, in the place set forth on the Omnibus Signature Page below, shall constitute agreement
to be bound by the terms and conditions hereof and the terms and conditions of the Registration Rights Agreement, with the same effect
as if each of such separate but related agreement were separately signed.

 

(t)                
Public Disclosure. Neither the Purchaser nor any officer, manager, director, member, partner, stockholder, employee,
Affiliate, Affiliated person or entity of the Purchaser shall make or issue any press releases or otherwise make any public statements
or make any disclosures to any third person or entity with respect to the transactions contemplated herein and will not make or issue
any press releases or otherwise make any public statements of any nature whatsoever with respect to the Company without the Company’s
express prior approval (which may be withheld in the Company’s sole discretion), except to the extent such disclosure is required
by Law, request of the staff of the SEC or of any regulatory agency or principal trading market regulations.

 

    	 	31	 

     

    

 

(u)               
Adjustments. In the event of any stock split, subdivision, dividend or distribution payable in shares of Common Stock (or
other securities or rights convertible into, or entitling the holder thereof to receive directly or indirectly shares of Common Stock),
combination or other similar recapitalization or event occurring after the date hereof, each reference in any Transaction Document to
a number of Shares or the Per Share Purchase Price shall be deemed to be amended to appropriately account for such event.

 

(v)               
Remedies. The parties hereto agree that irreparable damage would occur in the event that any of the provisions of this Agreement
were not performed by them in accordance with the terms hereof and that each party hereto may be entitled to seek protective orders, injunctive
relief and other remedies available at Law or in equity (including, without limitation, seeking specific performance or rescission of
purchases, sales and other transfers). The parties hereto agree not to raise any objections to the availability of the equitable remedy
of specific performance to prevent or restrain breaches of this Agreement by the Purchaser or the Company, as applicable, and to specifically
enforce the terms and provisions of this Agreement to prevent breaches or threatened breaches of, or to enforce compliance with, the respective
covenants and obligations of the Purchaser and the Company, as applicable, under this Agreement all in accordance with the terms of this
Section 5(v). Neither the Purchaser nor the Company, as applicable, shall be required to provide any bond or other security in connection
with seeking an injunction or injunctions to prevent breaches of this Agreement and to enforce specifically the terms and provisions of
this Agreement, all in accordance with the terms of this Section 5(v).

 

(w)             
Use of Proceeds. The Company shall use the net proceeds from the Offering to fund demonstrator products, to scale up manufacturing
processes and customer support in developing applications, and for working capital and other general corporate purposes.

 

[Signature page follows.]

 

IN WITNESS WHEREOF, the Company has duly executed
this Agreement as of the 27th day of January, 2022.

 

    	 	32	 

     

    

 

	 	SMARTKEM, INC. 
	 	 
	 	 
	 	By: 	/s/
    Robert Bahns
	 	Name: Robert Bahns 
	 	Title: Chief Financial Officer

  

    	 	33	 

     

    

 

SmartKem, Inc.

 

OMNIBUS SIGNATURE PAGE TO

 

SUBSCRIPTION AGREEMENT AND REGISTRATION RIGHTS
AGREEMENT

 

The undersigned, desiring to: (i) enter into
the Subscription Agreement, dated as of January 27, 2022 (the “Subscription Agreement”), between the undersigned,
“SmartKem, Inc., a Delaware corporation (the “Company”), and the other parties thereto, in the
form furnished to the undersigned, (ii) enter into the Registration Rights Agreement (the “Registration Rights Agreement”),
among the undersigned, the Company and the other parties thereto, in the form furnished to the undersigned, and (iii) purchase the Company’s
Shares as set forth in the Subscription Agreement and below, hereby agrees to join the Subscription Agreement and the Registration Rights
Agreement as a party thereto, with all the rights and privileges appertaining thereto, and to be bound in all respects by the terms and
conditions thereof. The undersigned specifically acknowledges having read the representations section in the Subscription Agreement entitled
 “Representations and Warranties of the Purchaser” and hereby represents that the statements contained therein are complete
and accurate with respect to the undersigned as a Purchaser.

 

IN WITNESS WHEREOF, the Purchaser hereby executes the Subscription
Agreement and the Registration Rights Agreement.

 

	Dated:    January 27, 2022	 	 	 	 	 	 
	 	 	 	 	 	 	 
	13,625                               	×	 	$2.00         	 	=	$27,250.00                                             
	Number of Shares	 	 	Purchase Price per Share	 		Total Purchase Price to be Paid

  

	PURCHASER (individual)	 	 	 	PURCHASER (entity)
	 	 	 	 	 
	
	 	 	 	
    Octopus Investments Nominees Limited 

	Signature	 	 	 	Name of Entity
	 	 	 
	
	 	 	 	By: 	/s/
    Simon P. King
	Print Name	 	 	 		Signature
	 	 	 
	
	 	 	 	Print Name: Simon P. King
	Signature (if Joint Tenants or Tenants in Common)	 	 	 	Title:	Partner
	 	 	 
	Address of Principal Residence:	 	 	 	Address of Executive Offices:
	
	 	 	 	
33 Holborn, EC1N 2HT, UK

	
		 	 	

	
	 	 	 	

	 	 	 
	Social Security Number(s):	 	 	 	IRS Tax Identification Number:
	
	 	 	 	

	 	 	 
	Telephone Number:	 	 	 	Telephone Number:
	
	 	 	 	
[**]

	 	 	 
	Facsimile Number:	 	 	 	Facsimile Number:
	
	 	 	 	

	 	 	 
	E-mail Address:	 	 	 	E-mail Address:
	
	 	 	 	
[**]

 

     

     

    

 

SmartKem, Inc.

OMNIBUS SIGNATURE PAGE TO

SUBSCRIPTION AGREEMENT AND REGISTRATION RIGHTS
AGREEMENT

 

The undersigned, desiring to: (i) enter into
the Subscription Agreement, dated as of January 27, 2022 (the “Subscription Agreement”), between the undersigned,
“SmartKem, Inc., a Delaware corporation (the “Company”), and the other parties thereto, in the
form furnished to the undersigned, (ii) enter into the Registration Rights Agreement (the “Registration Rights Agreement”),
among the undersigned, the Company and the other parties thereto, in the form furnished to the undersigned, and (iii) purchase the Company’s
Shares as set forth in the Subscription Agreement and below, hereby agrees to join the Subscription Agreement and the Registration Rights
Agreement as a party thereto, with all the rights and privileges appertaining thereto, and to be bound in all respects by the terms and
conditions thereof. The undersigned specifically acknowledges having read the representations section in the Subscription Agreement entitled
 “Representations and Warranties of the Purchaser” and hereby represents that the statements contained therein are complete
and accurate with respect to the undersigned as a Purchaser.

 

IN WITNESS WHEREOF, the Purchaser hereby executes the Subscription
Agreement and the Registration Rights Agreement.

 

	Dated:    January 27, 2022	 	 	 	 	 	 
	 	 	 	 	 	 	 
	986,375                               	×	 	$2.00         	 	=	$1,972,750.00                                             
	Number of Shares	 	 	Purchase Price per Share	 		Total Purchase Price to be Paid

  

	PURCHASER (individual)	 	 	 	PURCHASER (entity)
	 	 	 	 	 
	
	 	 	 	
    Octopus Titan VCT plc 

	Signature	 	 	 	Name of Entity
	 	 	 
	
	 	 	 	By: 	/s/ Simon P.King
	Print Name	 	 	 		Signature
	 	 	 
	
	 	 	 	Print Name: Simon P.King
	Signature (if Joint Tenants or Tenants in Common)	 	 	 	Title:	Partner
	 	 	 
	Address of Principal Residence:	 	 	 	Address of Executive Offices:
	
	 	 	 	
33 Holborn, EC1N 2HT, UK

	
		 	 	

	
	 	 	 	

	 	 	 
	Social Security Number(s):	 	 	 	IRS Tax Identification Number:
	
	 	 	 	

	 	 	 
	Telephone Number:	 	 	 	Telephone Number:
	
	 	 	 	
[**]

	 	 	 
	Facsimile Number:	 	 	 	Facsimile Number:
	
	 	 	 	

	 	 	 
	E-mail Address:	 	 	 	E-mail Address:
	
	 	 	 	
[**]

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