Document:

EX-10.1

  Exhibit 10.1

   

   

   

   

  First Amendment to License Agreement

   

  This First Amendment to License Agreement (“First Amendment”) is dated May 3, 2022 (“Effective Date”) and entered into by and between Cue Biopharma, Inc. (“Licensee”) and MIL 40G, LLC (“Licensor”).

   

  WHEREAS, Licensor and Licensee are parties to a certain License Agreement dated March 28, 2022 (“License Agreement”);

   

  WHEREAS, Licensee warrants and represents that, to the best of its knowledge, Licensor has fulfilled its obligations under the License Agreement and is not in default of any covenants or obligations contained in the License Agreement;

   

  WHEREAS, Licensor and Licensee desire to amend the License Agreement in certain respects as set forth herein; and,

   

  WHEREAS, all capitalized terms contained herein shall, unless otherwise defined in this First Amendment, have the same meaning as set forth in the License Agreement.

   

  NOW THEREFORE, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties agree that the License Agreement is hereby amended as follows:

   

  1.Licensed Premises. Effective July 15, 2022 (“Expanded Premises Commencement Date”) the License Agreement is hereby amended by (i) adding the attached Exhibit 1-A to the existing Exhibit 1, and (ii) adding the following sentences to the end of Section 1(a):

   

  The License shall be expanded to include Room 4101, as shown on the shaded portion of the floor plan attached hereto as Exhibit 1-A of this First Amendment (“Expanded Premises”), as part of the Licensed Premises. For the avoidance of doubt, Exhibit 1 of the License Agreement shall remain applicable, and the attached Exhibit 1-A shall be inserted immediately thereafter.

   

  2.Term. Section 2(a) of the Licensed Agreement is hereby modified be adding the following new sentences to the end of the Section:

   

  Unless terminated earlier in accordance with this Section 2, the term of this First Amendment (“Expanded Premises Term”) shall commence on the Expanded Premises Commencement Date and shall expire on the Expiration Date. Under no circumstance shall Licensor be liable to Licensee for failure to provide access to the Expanded Premises on or before the Expanded Premises Commencement Date, including but not limited to Force Majeure; provided, however, that if Licensor is unable to provide Licensee access to the Expanded Premises on or before the Expanded Premised Commencement Date, the Expanded Premised Commencement Date and Expanded Premises Expiration Date shall be extended by the number of days Licensor is unable to provide access to the Expanded Premises.

   

  3.License Fee. Section 3(a) of the License Agreement is hereby modified by adding the following new paragraph to the end of the Section:

   

  Effective the Expanded Premises Commencement Date, in addition to the existing License Fee, Licensee shall pay a monthly license fee of $9,000.00 for the Expanded Premises

   

  

  (“Expanded Premises Fee”), as shown on Schedule A attached hereto. Except as expressly stated otherwise herein, the Expanded Premises Fee shall be subject to all the same terms and conditions as the License Fee.

   

  4.Security Deposit. Section 3(d) of the License Agreement is hereby modified by adding the following new sentence to the end of the Section:

   

  In consideration of the Expanded Premises, the Security Deposit shall be increased from

  $225,760.20 to $235,883.98.

   

  5.Initial Payment. Section 3(e) of the License Agreement is hereby modified by adding the following new paragraph to the end of the Section:

   

  Immediately upon the execution of this First Amendment, Licensee shall pay an amount equal to the Expanded Premises Fee for the first month of the Expanded Premises Term ($9,000.00), the Expanded Premises Fee for the last month of the Expanded Premises Term ($10,123.78), as well as the increase in the Security Deposit commensurate with the addition of the Expanded Premises ($10,123.78). As such, Licensee shall pay a total of $29,247.56, on or before the execution of this First Amendment.

   

  6.Broker. Licensee warrants and represents that Licensee has dealt with no broker in connection with the consummation of this First Amendment, and, in the event of any brokerage claims asserted against Licensor predicated upon prior dealings with Licensee, Licensee agrees to defend the same and indemnify Licensor against any such claim.

   

  7.Ratification. Except as amended herein, all terms and conditions of the License Agreement shall remain unchanged and in full force and effect.

   

  8.Counterparts. This First Amendment to License Agreement may be executed in any number of counterparts, each of which shall be an original and all of which together shall constitute one and the same document.

   

   

  IN WITNESS WHEREOF, Licensor and Licensee have duly executed this First Amendment as of the date first written above.

   

   

  

   

  LICENSOR:

  By: /s/ Brian Taylor Name: Brian Taylor

  

  

  LICENSEE:

  By: /s/ Daniel Passeri Name: Daniel Passeri

   

  

   

  DocuSign Envelope ID: A39281AE-C0BB-4C29-A148-716C47C375D2

   

   

   

   

  Schedule A

   

  			
	 
Start
	 
End
	 
License Fee

	04/15/22
	07/14/22
	$200,700.00

	07/15/22
	04/14/23
	$209,700.00

	04/15/23
	04/14/24
	$218,088.00

	04/15/24
	04/14/25
	$226,811.52

	04/15/25
	04/14/26
	$235,883.98

   

  

   

  DocuSign Envelope ID: A39281AE-C0BB-4C29-A148-716C47C375D2

   

   

   

   

  Exhibit 1-AEX-10.2

   

  Exhibit 10_2

  	                                                                                   

  Rider to License Agreement Vivarium

   

  This Rider to License Agreement (“Rider”), is made as of July 7, 2022, by and between MIL 40G, LLC (“SmartLabs”), and Cue Biopharma, Inc. (“Licensee”).

   

  WHEREAS, SmartLabs and Licensee are parties to that certain License Agreement, as amended, dated March 28, 2022 (“License Agreement”). All capitalized terms used herein without definition shall have the meanings ascribed to them in the License Agreement. This Rider shall be governed by the terms of the License Agreement and if there is any conflict between the covenants and representations contained in the License Agreement and the Rider, the terms of the License Agreement shall prevail and be binding upon Licensor and Licensee;

   

  WHEREAS, all terms and conditions applied to, and all obligations imposed against, Licensee with respect to the “License”, “Licensed Premises” and/or “Occupants” (as defined in the License Agreement), shall be equally applied to the Vivarium License, Vivarium Premises and Vivarium Occupants (as herein defined); and

   

  NOW THEREFORE, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties agree as follows:

   

  1.Vivarium License. In addition to the License grated pursuant to the License Agreement, SmartLabs grants to Licensee the following, which shall constitute the Licensee’s vivarium license (the “Vivarium License”), solely to, (i) use as vivarium space consistent with current zoning for the Building and all applicable laws; (ii) conduct Licensee’s business; and (iii) collaborate with SmartLabs’ staff and other licensees in accordance with this Rider: (i) a non-transferable, non-assignable license to use one (1) standard private procedure room and two (2) standard private holding rooms, as shown on Exhibit 1 attached hereto (“Vivarium Premises”), subject to SmartLabs’ Rules and Regulations and pursuant to the terms of the Vivarium Service Agreement attached to this Rider as Exhibit 2 (“Vivarium Service Agreement”); provided, however that such use is approved by SmartLabs’ Institutional Animal Care and Use Committee (“IACUC”) in SmartLabs’ sole discretion, and further provided that all IACUC promulgated policies, guidelines and rules are followed without exception. For the avoidance of doubt the Service Agreement shall remain applicable, and the Vivarium Service Agreement shall supplement the same. In the event of conflict between the Service Agreement and Vivarium Service Agreement, the Vivarium Service Agreement shall control in relation to this Rider.

   

  2.Vivarium Occupants. In addition to the Occupants permitted pursuant to the License Agreement, during the Vivarium Term, the Vivarium License shall grant Licensee no more than twelve (12) additional Occupants (“Vivarium Occupants”) access to the Vivarium Premises and Shared Premises.

   

  3.Term. The term of this Rider (“Vivarium Term”) shall commence December 1, 2022 (“Vivarium Commencement Date”) and expire on November 30, 2024 (“Vivarium 

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  Expiration Date”). For the avoidance of doubt, in the event that the License Agreement is

   

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  terminated prior to its natural expiration due to a Licensee default during the Vivarium Term, then this Rider shall terminate as well.

   

  4.Vivarium Fee. Licensee shall pay a monthly license fee equal to $59,152.50, which Licensee shall pay in advance on or before the first day of each and every month during the Term (“Vivarium License Fee”). The Vivarium License Fee is subject to an automatic four percent (4%) increase on each anniversary of Vivarium Term Commencement Date, as shown on Schedule A attached hereto. Licensee shall pay the Vivarium License Fee payment by electronic payment to SmartLabs.

   

  5.Vivarium Security Deposit. Licensee shall pay a vivarium security deposit equal to

  $61,518.60 (“Vivarium Deposit”). The Vivarium Deposit shall be governed by the same terms as any Security Deposit as set forth in the Licenses Agreement.

   

  6.Initial Payment. Licensee shall pay, immediately upon executing this Rider, an amount equal to the Vivarium License Fee for the first month of the Vivarium Term ($59,152.50), the Vivarium License Fee for the last month of the Vivarium Term ($61,518.60), and the Vivarium Security Deposit. As such, Licensee shall pay a total of $182,189.70 on or before execution of this Rider.

   

  7.Brokerage. Licensee warrants and represents that Licensee has dealt with no broker in connection with the consummation of this Rider other than N/A (“Broker”), and, in the event of any brokerage claims asserted against SmartLabs predicated upon prior dealings with Licensee, Licensee agrees to defend the same and indemnify SmartLabs against any such claim.

   

  8.Ratification. Except as amended or modified herein, all terms and conditions of the License Agreement shall remain unchanged and in full force and effect.

   

  9.Counterparts. This Rider may be executed in any number of counterparts, each of which shall be an original and all of which together shall constitute one and the same document.

   

   

  IN WITNESS WHEREOF, SmartLabs and Licensee have duly executed this Rider as of the date first written above.

   

  SMARTLABS:	LICENSEE:

  							 

  	
	   /s/ Brian Taylor                                                                   /s/ Daniel R. Passeri

	  Name: Brian Taylor                                                             Name: Daniel R. Passeri

	  Title: Head of Field Operations                                           Title: Chief Executive Officer 

	 

	  

   

   

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  Schedule A

   

   

   

  			
	Start
	End
	Vivarium License Fee

	12/01/22
	11/30/23
	$	59,152.50

	12/01/23
	11/30/24
	$	61,518.60

   

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  Exhibit 1

   

   

  40 Guest Street, Vivarium

   

   

  *Furniture and equipment layout are shown for illustrative purposes only.

   

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  Exhibit 2

  Vivarium Service Agreement

   

   

  1.Vivarium License Services. The following is an exhaustive list of all supplies, equipment and services included in the cost of each Vivarium License Fee (“Vivarium License Services”):

   

  a.Included Supplies

  i.Vivarium supplies: water bottles, bedding, food and environmental enhancements (e.g. nestlets, Shepard Shacks or functionally equivalent etc.)

  ii.Standard laboratory technician supplies (e.g. gloves, lab coats, safety glasses and dust masks)

  b.Included Holding Room Equipment

  i.IVC Holding racks equipped with disposable IVC rodent cages

  ii.Transfer station

  c.Included Procedure Room Equipment

  i.Biosafety Cabinet

  ii.Bench-top space with lab chair

  iii.Handwash sink

  iv.CO2 gas supply

  v.Anesthetic vaporizer

  d.Included Services

  i.Animal Care Technicians

  ii.Veterinary and IACUC oversight and frequent program reviews

  iii.Twenty-four hour access to animal holding room and procedure space

  iv.Cage changes every 2 weeks for mice and every week for rats, or as	needed. More frequent changes are at additional cost

  v.Daily food, water and health checks

  vi.Quarterly Sentinel Health Surveillance testing

  vii.High-speed broadband WiFi internet

   

  2.Extra Services. The following is a non-exhaustive list of supplementary supplies, equipment and services available to Licensee upon request and at additional cost to Licensee beyond the Vivarium License Fee:

   

  a.General

  i.Animal models

  ii.Any additional services that will require a research technician

  iii.Transportation, health reports, quarantine and Quarterly Sentinel Health Surveillance screening required for incoming animals from suppliers other than Charles River Laboratories, the Jackson Laboratory, Envigo and Taconic

  b.Specialized Training

  c.Technical Services:

  i.Dosing

  1)Core Hour Dosing

  2)Outside Core Hour Dosing

  ii.Bleed

  1)Routine Bleed Route (IV, RO, submandibular, terminal, submental)

  2)After Core Technician Hours Bleed

   

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  iii.Euthanasia/necropsy

  1)Technician completes euthanasia

  2)Technician completes necropsy

  iv.Other

  1)Sample labeling

  2)Tissue sample / Organ harvesting

  v.Surgery (Pricing depends on the species/quantity and type of surgery)

  In electing to have SmartLabs provide any Technical Services or Specialized Training on behalf of Licensee, Licensee agrees to release and waive any and all claims against SmartLabs for injury or damage to person, property or business of every kind, nature and description, sustained in in relation to any such Technical Services or Specialized Training, other than by reason of gross negligence or willful misconduct of SmartLabs.

  d.Supplies/Materials:

  i.Non-standard gases (cost estimate driven by quantity needed)

  ii.Non-standard medications/drugs (cost estimate driven by quantity needed)

  iii.Additional lab supplies and non-controlled drugs (Controlled Substances would need to be procured by licensee)

  e.Husbandry Services: including but not limited to,

  i.Application/removal of non-standard diet

  ii.Application/removal of moist feed

  iii.Application/removal of treated water

  iv.Weaning

  v.Tumor measurements

  vi.Body weights

  vii.Animal identification (does not include tag or microchip) viii.Animal preparations (e.g., shaving)

  f.Equipment

  i.Licensee may request to add an additional 88-cage IVC Holding Rack upon thirty (30) days advance written notice to SmartLabs, subject to availability, and for a monthly fee of $3,900.00.

   

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  The following services are not provided and/or are not included in License. When available, these services can be provided under a separate agreement with different terms.

   

  	
	Any research/work required to be conducted under Biosafety Levels (BSL) 3 or 4 policies and
guidelines.

	Use of any radioactive material.
Radiation producing equipment (including lasers) will need special approval

	IT Support that involves system changes or any operation that involves elevated or administrative privileges OR that requires configuration of software, hardware, or applications that are not owned or
provided by SmartLabs.

	Exclusive access to Licensor-owned shared equipment

	Specific Training such as RCRA, DOT, cyanide, etc.

	Exclusive use of shared and common spaces

	Private Conference Rooms

	Special PPE

	Facsimile Services

	Shipping of Packages

	Costs of moving in and moving out

	Certification and Preventative Maintenance of company owned equipment

	Use of Licensor’s accounts for purchases

	 

   

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