Document:

ex10-52.htm

     

    EXHIBIT
10.52

     

    

    AMENDMENT
TO RETIREMENT AGREEMENT

     

    This
agreement (the “Amendment”) is entered into as of September 14, 2009 (the
“Effective Date”) by Kuslima Shogen (“Shogen”) and Alfacell Corporation, a
Delaware corporation (“Alfacell”).

     

    WHEREAS,
Shogen and Alfacell are parties to a Retirement Agreement dated as of April 25,
2008 (the “Retirement Agreement”);

     

    WHEREAS,
Alfacell is seeking financing required to enable it to continue its operations
and continue to pursue the development of its pharmaceutical
products;

     

    WHEREAS,
Alfacell believes that it must reduce its outstanding obligations, including its
obligations to Shogen under the Retirement Agreement, in order to obtain such
financing;

     

    WHEREAS,
as the founder, former Chief Executive Officer and currently a director and
stockholder of Alfacell, Shogen wishes to see Alfacell obtain such financing,
continue its operations and successfully complete development of its
pharmaceutical products; and

     

    WHEREAS,
Shogen and Alfacell wish to amend the Retirement Agreement as provided
herein.

     

    NOW
THEREFORE, in consideration of the mutual promises and undertakings of the
parties, it is hereby agreed as follows:

     

    1.           Commencing
as of September 14, 2009, the periodic payments payable to Shogen under Section
2(a) of the Retirement Agreement (the “Periodic Payments”) will be paid at the
rate of $150,000 per year rather than at the rate of $300,000 per year as
currently provided in Section 2(a) of the Retirement Agreement, provided that
Shogen shall be entitled to retain all payments received from Alfacell pursuant
to Section 2(a) of the Retirement Agreement from the Termination Date through
September 14, 2009.  Pursuant to the foregoing amendment to the rate
of Periodic Payments, the Periodic Payments during the period from September 14,
2009 through March 31, 2010 shall total $81,250 and the Periodic Payments during
the period from April 1, 2010 through March , 31, 2011 shall total
$150,000.

     

    2.           The
amount of the Continuing Payments payable to Shogen pursuant to Section 3(b)(v)
of the Retirement Agreement shall be changed such that Shogen shall receive
payments equal to (i) 5% of any royalties payable with respect to net sales
which are received by Alfacell pursuant to any and all license agreements
entered into by Alfacell for the marketing and distribution of Licensed Products
rather than the 15% of any such royalties currently set forth in Section 3(b)(v)
of the Retirement Agreement and (ii) 2% of net sales which Alfacell books on its
financial statements rather than the 5% of such net sales currently set forth in
Section 3(b)(v) of the Retirement Agreement, provided that Shogen shall receive
such revised Continuing Payments only to the extent and under the conditions set
forth in Section 3(b)(v) of the Retirement Agreement. All references to 15% in
Section 3(b)(v) of the Retirement Agreement shall be changed to 5% and all
references to 5% in Section 3(b)(v) of the Retirement Agreement shall be changed
to 2%.

     

    3.           In
the event Alfacell shall obtain a positive result in a clinical trial for
ONCONASE®,
Shogen shall be entitled, within 20 business days after Alfacell becomes aware
of such positive result, to receive cash payments or shares of common stock or a
combination of cash and common stock, equal to the amount by which the aggregate
amount of the Periodic Payments actually paid to Shogen during the two year
period following the Termination Date is less than $600,000. Alfacell shall have
the option to make such payment in cash, common stock or a combination thereof.
Any shares of common stock of Alfacell issued to Shogen pursuant to this Section
3 shall not be registered under the Securities Act of 1933 and shall be valued
at the closing price of the common stock on the last trading day before such
common stock is issued. If for any reason, the common stock of Alfacell is not
publicly traded at the time of its issuance it will be valued in good faith by
the board of directors of Alfacell. For purposes of this Section 3, a positive
result in a clinical trial for ONCONASE® shall
be marketing approval of ONCONASE® by
the FDA or EMEA for any indication.

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

    4.         This
Amendment shall be binding on the parties as of the Effective Date, provided
however that the changes to the Retirement Agreement provided in Sections 1, 2
and 3 hereof shall not go into effect unless and until Alfacell shall obtain
additional debt or equity financing subsequent to the Effective
Date.  Since such additional financing will not be obtained until
after September 14, 2009, Periodic Payments made after the date such financing
is obtained will be adjusted so that Periodic Payments made during the period
from September 14, 2009 through March 31, 2011 shall total $231,250 as provided
in Section 1 hereof.

    

    5.         Alfacell
and Shogen acknowledge that they have each had sufficient opportunity to review
the terms of this Amendment and to consult with advisors and attorneys of their
choice concerning its terms and conditions. Shogen acknowledges that she fully
and completely understands the terms of this Amendment and their significance,
and that she accepts those terms and enters into this Amendment freely and
voluntarily thereby binding herself, her heirs, successors, personal
representatives and assigns. Shogen warrants that she is fully competent to
enter into this Amendment.

    

    6.         All
capitalized terms used herein and not defined herein shall have the meaning
assigned to such terms in the Retirement Agreement.

    

    7.         Except
as specifically amended herein, all of the terms and conditions of the
Retirement Agreement and the Release Agreement shall remain in full force and
effect.

    

    8.           This
Amendment, together with the Retirement Agreement, contain the entire
understanding of the parties, and there are no additional promises,
representations, assurances, terms or provisions between the
parties.

     

    9.         This
Amendment may be executed in separate counterparts, each of which shall be
considered an original but all of which shall constitute one
agreement.

    

    
      	
              AGREED
      AND ACCEPTED:

            	 
      
	
              ALFACELL
      CORPORATION

            	 
      
	 	 
	

              By:  /s/ Charles
      Muniz

              Name:  Charles
      Muniz

              Title:  President

            	

              /s/
      Kuslima Shogen 

                Kuslima
      ShogenUnassociated Document

    
      
        

        

      

      EXHIBIT
10.1

      

      

      

       

      

      FLORIDA
DEPARTMENT OF STATE

      DOING
BUSINESS QUALIFICATION OF

      PHYSICIANS
HEALTHCARE MANAGEMENT GROUP, INC.

       

       

       

       

      
 

      
        
           

        

        
          1

          
            

          

        

        
           

        

      

      [State
Seal]

      FLORIDA
DEPARTMENT OF STATE

      Division
of Corporation

      

      December
8, 2006

      

      

      FIDEL
RODRIGUEZ

      700 S.
ROYAL POINCIANA BLVD STE 506

      MIAMI, FL
33166

      

      

      Qualification
documents for PHYSICIANS HEALTHCARE MANAGEMENT GROUP, INC. were filed on
December 8, 2006 and assigned document number F06000007576.

      Please
refer to this number whenever corresponding with this office.

      

      Your
corporation is now qualified and authorized to transact business in Florida as
of the file date.

      

      The
certification you requested is enclosed.

      

      A
corporation annual report/uniform business report will be due this office
between January 1 and May 1 of the year following the calendar year of the file
date.  A Federal Employer Identification (FEI) number will be required
before this report can be filed.  If you do not already have an FEI
number, please apply NOW with the Internal Revenue by calling 1-800-829-3676 and
requesting form SS-4.

      

      Please be
aware if the corporate address changes, it is the responsibility of the
corporation to notify this office.

      

      Should
you have any questions regarding this matter, please contact this office at the
address given below.

      

      Tim
Burch

      Document
Specialist

      New
filing Section

      Division
of
Corporations                                                                                                                                                                                                                                                    Letter
Number: 406A00070329

      

      

      P.O. BOX
6327 – Tallahassee, Florida 32314

      

      

        
          
             

          

          
            2

            
              

            

          

          
             

          

        

      [State
Seal]

      

      

      I certify
the attached is a true and correct copy of the application by PHYSICIANS
HEALTHCARE MANAGEMENT GROUP, INC., a Nevada corporation, authorized to transact
business within the State of Florida on December 8, 2006 as shown by the records
of this office.

      

      The
document number of this corporation is F06000007576.

      

      

      

      

      

      [State
Seal]

      

        
          
             

          

          
            3

            
              

            

          

          
             

          

        

      [FILED
2006 DEC-8 PM 2:59

      SECRETARY
OF STATE

      TALLAHASSE
FLORIDA]

      

      APPLICATION
BY FOREIGN CORPORATION FOR AUTHORIZATION TO TRANSACT

      BUSINESS
IN FLORIDA

      

      IN
COMPLIANCE WITH SECTION 067.1503, FLORIDA STATUTES, THE FOLLOWING IS SUBMITTED
TO REGISTER A FOREIGN CORPORATION TO TRANSACT BUSINESS IN THE STATE OF
FLORIDA

       

      
      

       

      
        	1.	
                PHYSICIANS HEALTHCARE MANAGEMENT GROUP,
      INC.

              
	 	
                (Enter
      name of corporation; must include “INCORPORATED,” “COMPANY,”
      “CORPORATION,” “Inc.” “Co., “Corp.,” “Inc,” “Co,” or
    “Corp”)

              
	 	 
	 	
                (If
      name unavailable in Florida, enter alternative corporate name adopted for
      the purpose of transacting business in
Florida)

              

      

       

      
        	2.	    NEVADA	3.	    42-1639683
	 	(State
      or country under the law of which it is incorporated)	 	(FEI
      number, if applicable)
	 	 	 	 
	4.	    12/20/1996	5.	    PERPETUAL
	 	
                    (Date
      of incorporation)

              	 	(Duration: Year
      corp. will cease to exist or “perpectual”)
	 	 	 	 
	6.	 
	 	(Date
      first transacted business in Florida, if prior to registration)
      

                
                  (SEE
      SECTIONS 607.1501 & 607.1502, F.S., to determine penalty
      liability)

                

              
	 	 	 	 
	7.	700
      S. ROYAL POINCIANA BLVD., SUITE 506    MIAMI, FL.
      33166 
	 	
                
                  (Principal
      office address)

                

              
	 	 	 	 
	 	
                700 S. ROYAL POINCIANA BLVD., SUITE
      506    MIAMI, FL. 33166 

                  (Current
      mailing address)

                

              
	 	 	 	 
	8.	
                TO ENGAGE IN ANY AND ALL BUSINESS ACTIVITIES
      PERMITTED IN THE STATE OF
FLORIDA

              

      

       

      
        	
                9.

              	
                Name
      and street
      address of Florida registered agent:  (P.O. Box NOT
      acceptable)

              

      

       

      
        	 	
                Name:

              	    ROBERT
      TRINKA	 	 
	 	 	 	 	 
	 	Office
      Address: 	700 S. ROYAL
      POINCIANA BLV, SUITE 506	 	 
	 	 	 	 
	 	MIAMI	,Florida	33166	 
	 	(City)	
              	(Zip code)	 

      

       

      
      

      
      

      
        	
                10.

              	
                Registered
      agent’s acceptance:

              

      

      Having
been named as registered agent and to accept service of process for the above
stated corporation at the place designated in this application, I hereby accept
the appointment as registered agent and agree to act in this
capacity.  I further agree to comply with the provisions of all
statues relative to the proper and complete performance of my duties, and I am
familiar with and accept the obligations of my position as registered
agent.

       

       

      
        	 	/s/ Robert
      Trinka	 
	 	(Registered agent’s
      signature)	 

      

       

      11.  Attached
is a certificate of existence duly authenticated, not more than 90 days prior to
delivery of this application to the Department of State, by the Secretary of
State or other official having custody of corporate records in the jurisdiction
under the law of which it is incorporated.

      

      
        
           

        

        
          4

          
            

          

        

        
           

        

      

      [FILED
2006 DEC-8 PM 2:59

      SECRETARY
OF STATE

      TALLAHASSE
FLORIDA]

      

      
        	
                 
      

              	
                12. Name and business
      address of officers and/or
directors:

              

      

      

      
        	
                A.

              	
                DIRECTORS

              

      

      

      
        	
                Chairman:

              	
                ROBERT TRINKA

              	 

      

      

      
        	
                Address:

              	
                700 S. ROYAL POINCIANA BLVD, SUITE
      506

              	 

      

      

      
        	                                
    	
                MIAMI, FL 33166

              	 

      

      

      
        	
                Vice
      Chairman:

              	
                FIDEL RODRIGUEZ

              	 

      

      

      
        	
                Address:

              	
                700 S. ROYAL POINCIANA BLVD, SUITE
      506

              	 

      

      

      
        	                               
    	
                MIAMI, FL 33166

              	 

      

      

      
        	
                Director:

              	
                RICHARD GOULDING

              	 

      

      

      
        	
                Address:

              	
                817 HOGAN WAY

              	 

      

      

      
        	 	
                MELBOURNE, FL 32940

              	 

      

       

      
        	
                B.

              	
                OFFICERS

              

      

       

      
        	President:	ROBERT
    TRINKA	 

      

       

      
        	
                Address:

              	
                700 S. ROYAL POINCIANA BLVD, SUITE
      506

              	 

      

      

      
        	 	
                MIAMI, FL 33166

              	 

      

      
      

       

      
        	Vice
      President:  	FIDEL
      RODRIGUEZ	 

      

       

      
        	
                Address:

              	
                700 S. ROYAL POINCIANA BLVD, SUITE
      506

              	 

      

      

      
        	
              	
                MIAMI, FL 33166

              	 

      

       

      
        	Secretary: 	RICHARD
      GOULDING 	 

      

       

      
        	
                Address:

              	
                817 HOGAN WAY, MELBOURNE, FL
      32940

              	 

      

       

      
        	Treasury: 	FIDEL RODRIGUEZ 	 

      

       

      
        	
                Address:

              	
                700 S. ROYAL POINCIANA BLVD, SUITE 506, MIAMI, FL
      33166

              	 

      

      

      NOTE:  If
necessary you may attach an addendum to the application listing additional
officers and/or directors.

       

      
        	13. 	/s/ Robert
      Trinka 	 
	 	(Signature of
      Director or Officer listed in number 12 of the application)	 
	 	 	 
	14.	ROBERT
    TRINKA	 
	 	(Typed or printed
      name and capacity of person signing application)	 

      

       

      
        
           

        

        
          5

          
            

          

        

        
           

        

      

      [FILED
2006 DEC-8 PM 2:59

      SECRETARY
OF STATE

      TALLAHASSE
FLORIDA]

      

      [State
Seal]

      

      CERTIFICATE
OF EXISTENCE

      WITH
STATUS IN GOOD STANDING

      

      I, DEAN
HLLER, the duly elected and qualified Nevada Secretary of State, do hereby
certify that I am, by the laws of said State, the custodian of he records
relating to filings by corporations, non-profit corporations, corporation soles,
limited-liability companies, limited partnerships, limited-liability
partnerships and business trust pursuant to Title 7 of the Nevada Revised
Statues which are either presently in a status of good standing or were in good
standing for a time period subsequent of 1976 and am the proper officer to
execute this certificate.

      

      I further
certify that the records of the Nevada Secretary of State, at the date of this
certificate, evidence, PHYSICIANS HEALTHCARE MANAGEMENT GROUP, INC., as a
corporation duly organized under the laws of Nevada and existing under and by
virtue of the laws of the State of Nevada since December 20, 1996, and is in
good standing in this state.

      

      

      

      [State
Seal]

      

        
          
             

          

          
            6

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