Document:

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CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED BY BRACKETS,
HAS BEEN OMITTED PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT PURSUANT TO
RULE 24B-2 UNDER THE SECURITIES EXCHANGE ACT OF 1934, AS AMENDED. THE OMITTED
MATERIAL HAS BEEN FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION.

[ILLUMINA LOGO]

                                                                   Exhibit 10.31

February 15, 2005

Alan Kersey

Re:  Illumina, Inc.

Dear Alan:

It gives me great pleasure to set forth the principal terms for you to join
Illumina, Inc. (the "Company").

Position:                 VP & Site General Manager

Responsibilities:         VP/Site General Manager is a position of scientific
                          and technical leadership for the CyVera subsidiary
                          upon the merger with Illumina, Inc. Principal
                          responsibilities will include:

                          o     Direct leadership of the CyVera subsidiary.

                          o     Development of strategies for the CyVera
                                business.

                          o     Participation with the senior management team to
                                define future products.

                          o     Achievement of the CyVera business and
                                financial goals.

                          o     Other such matters that may be determined by the
                                management team.

                          As a Company employee you will be expected to abide by
                          all the Company policies and procedures and sign and
                          comply with the Company's standard form of Proprietary
                          Information and Inventions Agreement, which prohibits
                          unauthorized use or disclosure of the Company's
                          proprietary information. In compliance with

                                          Page 1
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CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED BY BRACKETS,
HAS BEEN OMITTED PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT PURSUANT TO
RULE 24B-2 UNDER THE SECURITIES EXCHANGE ACT OF 1934, AS AMENDED. THE OMITTED
MATERIAL HAS BEEN FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION.

                          federal immigration law, you will be required to
                          provide documentary evidence of your identity and
                          eligibility of employment in the United States.

Reporting: (Direct Mgr)   Reporting to Jay Flatley, President and CEO with a
                          dotted line to John Stuelpnagel, COO.

Compensation:             For full-time regular employment, your base salary
                          will be $8,461.54, payable every other week, one week
                          in arrears and subject to standard payroll deductions
                          and withholdings. Your first paycheck will be prorated
                          based on your employment start date.

Equity:                   Subject to approval by the Stock Option Committee, you
                          will be granted an option to purchase 100,000 shares
                          of Common Stock at a purchase price equal to the
                          closing price of such shares on your first day of
                          employment. The shares are subject to vesting over a
                          five-year period, with 60 monthly vesting increments.
                          The options will be granted pursuant to the Company's
                          2000 Stock Plan.

Incentive Options:        Additionally, with Stock Option Committee approval,
                          you will be granted an Incentive Option for an
                          additional 100,000 shares. These shares will have
                          default vesting of 1/12 per month beginning in year 9
                          from the grant date. Vesting will accelerate as to 25%
                          of the incentive share options based on achievement of
                          each of the following 4 milestones: [*]

Management Bonus:         You will be entitled to participate in our Executive
                          Bonus Plan at a 20% target level. This will be
                          prorated based on the number of full months that you
                          are on the Illumina payroll. We will be developing the
                          bonus plan shortly; however, it will be based 2/3 on
                          achievement of 2005 financial goals and 1/3 on
                          achievement of personal goals.

Benefits:                 You will be entitled to receive the Company's standard
                          benefits. These include medical, dental and vision
                          insurance, which begin the first day of the following
                          month after joining Illumina. Life insurance,
                          long/short-term disability insurance, and employee
                          assistance plan begin on your date of joining. A 40l
                          (k) plan is also available.

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CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED BY BRACKETS,
HAS BEEN OMITTED PURSUANT TO A REQUEST FOR CONFIDENTIAL TREATMENT PURSUANT TO
RULE 24B-2 UNDER THE SECURITIES EXCHANGE ACT OF 1934, AS AMENDED. THE OMITTED
MATERIAL HAS BEEN FILED SEPARATELY WITH THE SECURITIES AND EXCHANGE COMMISSION.

Employment at Will:       Your employment will be at-will, which means it may be
                          terminated at any time by you or the Company for any
                          reason or for no reason. This at-will employment
                          relationship cannot be changed except by written
                          agreement signed by the CEO of the Company.

Start Date:               Your first day of full-time regular employment is
                          considered to be the date of the close of the
                          merger.

Expiration of Offer:      This offer will be valid for 30 days from receipt of
                          this letter.

This letter contains the complete, final and exclusive embodiment of the terms
of your employment with the Company. This letter shall be governed by California
law without regard to conflict of laws principles.

We hope that you will join us in building a preeminent life sciences company. If
the foregoing accurately reflects our agreement, please so indicate by signing
where indicated below and returning the enclosed duplicate copy of this letter
to me.

Sincerely,

Jay Flatley
President and CEO
Illumina, Inc.

The foregoing is agreed and accepted.

-------------------------------------------        -----------------------------
                Alan Kersey                                    Date

                                     Page 3<PAGE>

                                                                   Exhibit 10.32

April 8, 2005

Paul Grint, MD

Re: Illumina, Inc. Board Position

Dear Paul,

I am pleased to offer you an appointment to the Board of Directors of Illumina,
Inc. You will be appointed to serve in the class of Directors whose term expires
in 2007. At that time you will be subject to re-election on a three year term.
The effective date of your appointment will be Tuesday, April 12, 2005.

Your compensation as a Board Member will be as specified in Illumina's standard
policies for Director Compensation. Specifically, this consists of:

      -     $2,500 as a quarterly retainer.

      -     $2,000 additional compensation for attendance at each board meeting.

      -     $1,000 additional compensation for attendance at each committee
            meeting.

In addition, you will be awarded Illumina stock options according to the
following schedule:

      -     20,000 shares of Illumina stock will be awarded to you upon your
            election to the Board.

      -     Thereafter you will receive an additional 10,000 shares at each
            annual board meeting, provided that you have served on the Board for
            at least six calendar months prior to the date of the next annual
            stockholder meeting.

      -     These shares will vest over a four (4) year period on an annual
            vesting basis.

We look forward to working with you as a member of the Board in building a
preeminent life sciences company.

Sincerely,

Jay Flatley
President & CEO
Illumina, Inc.

Agreed and accepted.

_____________________________       ________________________________
        Name                                     Date<PAGE>

[LOGO ILLUMINA]

                                                                   Exhibit 10.33

April 26, 2005

Christian Henry

Re: Illumina, Inc.

Dear Christian;

It gives me great pleasure to set forth the principal terms for you to join
Illumina, Inc. (the "Company").

Position:              VP and Chief Financial Officer

Responsibilities:      The VP and Chief Financial Officer is a position of both
                       strategic and functional leadership having primary
                       responsibility for the overall financial activities of
                       the Company as well as being involved in the architecture
                       of the Company's financial and business vision. Principal
                       responsibilities include:

                         -  Participating as a key member of the management team
                            in corporate strategic planning,

                         -  Developing the financial goals and strategy of the
                            company,

                         -  Providing management and financial reporting to the
                            operating groups of the company,

                         -  Ensuring the company is well funded through an
                            appropriate combination of equity and debt
                            financings,

                         -  Leading the annual financial planning process,

                         -  Over time, developing as a key contact for Wall
                            Street analysts and investors,

                         -  Implementing the financial aspects of the company's
                            ERP system,

                         -  Maximizing the return on investment of the company's
                            cash resources while maintaining a suitable risk
                            profile,

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                              -  Assuming a leadership role in corporate
                                 acquisition activities,

                              -  Coordinating the corporate risk management
                                 program,

                              -  Minimizing corporate tax obligations,

                              -  Negotiating lines of credit,

                              -  Recruiting key personnel into the finance team,

                              -  Managing the corporate facilities program,

                              -  Participating in contract negotiations,

                              -  Other such matters that may be determined by
                                 the management team.

                            As a Company employee you will be expected to abide
                            by all the Company policies and procedures and sign
                            and comply with the Company's standard form of
                            Proprietary Information and Inventions Agreement,
                            which prohibits unauthorized use or disclosure of
                            the Company's proprietary information. In compliance
                            with federal immigration law, you will be required
                            to provide documentary evidence of your identity and
                            eligibility of employment in the United States.

Reporting: (Direct Mgr)     Reporting to Jay Flatley, President and CEO.

Compensation:               For full-time regular employment, your base salary
                            will be $9,230.77, payable every other week, one
                            week in arrears and subject to standard payroll
                            deductions and withholdings. Your first paycheck
                            will be prorated based on your employment start
                            date.

Equity:                     Subject to approval by the Stock Option Committee,
                            you will be granted an option to purchase 100,000
                            shares of Common Stock at a purchase price equal to
                            the closing price of such shares on your first day
                            of employment. The shares are subject to standard
                            vesting over a five-year period, with 20% of the
                            shares vesting after one year from employment Start
                            Date of your full-time employment and thereafter
                            1/60th per month for the remaining 48 months. The
                            options will be granted pursuant to the Company's
                            2000 Stock Plan.

Executive Bonus:            You will participate in our Executive Bonus Plan at
                            a 25% level. Your first year's pay out will be
                            prorated, based on the number of full months that
                            you are on board. Plans are currently being
                            developed, and are based on both

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                            Corporate financial targets (2/3 of pay out) and
                            personal objectives (1/3 of pay out).

Relocation:                 Provided that you relocate to within 25 miles of
                            Illumina within 2 years of your start date, you will
                            receive $20,000 as relocation compensation. This
                            amount is subject to standard payroll deductions and
                            withholdings, and payable on your first payday after
                            you complete your move. If you voluntarily leave the
                            Company within one (1) year of your relocation date,
                            you will be required to pay back a prorated amount.

Benefits:                   You will be entitled to receive the Company's
                            standard benefits. These include medical, dental and
                            vision insurance, which begin the first day of the
                            following month after your hire. Life insurance,
                            long/short-term disability insurance, employee
                            assistance plan and 401(k) begin on your date of
                            hire.

Employment at Will:         Your employment will be at-will, which means it may
                            be terminated at any time by you or the Company for
                            any reason or for no reason. This at-will employment
                            relationship cannot be changed except by written
                            agreement signed by the CEO of the Company.

Start Date:                 Your first day of full-time regular employment will
                            be May 23, or an otherwise mutually agreeable date.

Expiration of Offer:        This offer will be valid for 7 days from the date
                            of this letter.

This letter contains the complete, final and exclusive embodiment of the terms
of your employment with the Company. This letter shall be governed by California
law without regard to conflict of laws principles.

Christian, we are very excited about the prospects of working together and hope
that you will join us in building a pre-eminent life sciences company. If the
foregoing accurately reflects our agreement, please so indicate by signing where
indicated below and returning the enclosed duplicate copy of this letter to me.

Sincerely,

Jay Flatley
President and CEO
Illumina, Inc.

The foregoing is agreed and accepted.

_____________________________________           _______________________________
         Christian Henry                                   Date

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