Document:

Exhibit 4.4

 

SERIES B WARRANT

 

RUTHIGEN,
inc.

 

	Warrant Shares: [*]	Issue Date: _____________

 

THIS SERIES B WARRANT
(the “Warrant”) certifies that, for value received, _____________ (the “Holder”) is entitled,
upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the
Issue Date and on or prior to the close of business on the five (5) year anniversary of the Issue Date (the “Termination
Date”) but not thereafter, to subscribe for and purchase from Ruthigen, Inc., a Delaware corporation (the “Company”),
up to [*] shares (the “Warrant Shares”) of the Company’s common stock, par value $0.0001 per share
(“Common Stock”). The initial number of Warrant Shares shall be an amount to equal to the number of shares of
Common Stock the Holder has purchased from the Company on the Issue Date (rounded (up or down) to the nearest whole Warrant Share).
The purchase price of one share of Common Stock under this Warrant shall be equal to the Exercise Price, as defined in Section
2(b).

 

Section 1.          Definitions.
Capitalized terms used and not otherwise defined herein shall have the meanings set forth in that certain Warrant Agent Agreement
between the Company and VStock Transfer, LLC (the “Warrant Agent”), dated as of March ____, 2014 (the “Warrant
Agent Agreement”).

 

Section 2.          Exercise.

 

a)        Exercise
of Warrant. Exercise of the purchase rights represented by this Warrant may be made, in whole or in part, at any time or times
on or after the Issue Date and on or before the Termination Date by delivery (whether via facsimile or otherwise) to the Warrant
Agent or such other office or agency of the Company as it may designate by notice in writing to the registered Holder at the address
of the Holder appearing on the books of the Company or the Warrant Agent of a duly executed copy of the Notice of Exercise form
annexed hereto. No ink-original Notice of Exercise shall be required, nor shall any medallion guarantee (or other type of guarantee
or notarization) of any Notice of Exercise form be required. Within two (2) Trading Days following an exercise of this Warrant
as aforesaid (the “Price Delivery Date”), the Holder shall deliver payment to the Warrant Agent of an amount
equal to the aggregate Exercise Price of the Warrant Shares thereby purchased, payable to the order of the Company, by wire transfer
or cashier’s check drawn on a United States bank or, if available, pursuant to the Cashless Exercise procedure specified
in Section 2(c) below. Notwithstanding anything herein to the contrary, the Holder shall not be required to physically surrender
this Warrant to the Company or the Warrant Agent until the Holder has purchased all of the Warrant Shares available hereunder and
the Warrant has been exercised in full, in which case, the Holder shall surrender this Warrant to the Warrant Agent for cancellation
within three (3) Trading Days after the date the final Notice of Exercise is delivered to the Warrant Agent. Partial exercises
of this Warrant resulting in purchases of a portion of the total number of Warrant Shares available hereunder shall have the effect
of lowering the outstanding number of Warrant Shares purchasable hereunder in an amount equal to the applicable number of Warrant
Shares purchased. The Holder and the Company or the Warrant Agent shall maintain records showing the number of Warrant Shares purchased
and the date of such purchases. The Company or the Warrant Agent shall deliver any objection to any Notice of Exercise form within
2 Business Days of receipt of the applicable Notice of Exercise. The Holder and any assignee, by acceptance of this Warrant,
acknowledge and agree that, by reason of the provisions of this paragraph, following the purchase of a portion of the Warrant Shares
hereunder, the number of Warrant Shares available for purchase hereunder at any given time may be less than the amount stated on
the face hereof.

 

    	 

    	 

    

 

b)          Exercise
Price. The exercise price per share of the Common Stock under this Warrant shall be $_______[125% of the IPO Price],
subject to adjustment as provided hereunder (the “Exercise Price”).

 

c)          Cashless
Exercise. If at the time of exercise hereof there is no effective registration statement registering, or the prospectus contained
therein is not available for, the issuance of the Warrant Shares to the Holder, then this Warrant may only be exercised, in whole
or in part, at such time by means of a “cashless exercise” (a “Cashless Exercise”). In no event
will the Company be required to net cash settle the Warrant exercise. In a Cashless Exercise, the Holder shall be entitled to receive
a number of Warrant Shares equal to the quotient obtained by dividing [(A-B) (X)] by (A), where:

 

(A) = the
VWAP on the Trading Day immediately prior to the date on which Holder elects to exercise this Warrant by means of a Cashless Exercise,
as set forth in the applicable Notice of Exercise;

 

(B) = the Exercise
Price of this Warrant, as adjusted hereunder; and

 

(X) = the number
of Warrant Shares that would be issuable upon exercise of this Warrant in accordance with the terms of this Warrant if such exercise
were by means of a cash exercise at the Exercise Price rather than a Cashless Exercise.

 

““VWAP”
means, for any date, the price determined by the first of the following clauses that applies: (a) if the Common Stock is then listed
or quoted on a Trading Market, the daily volume weighted average price of the Common Stock for such date (or the nearest preceding
date) on the Trading Market on which the Common Stock is then listed or quoted as reported by Bloomberg L.P. (based on a Trading
Day from 9:30 a.m. (New York City time) to 4:02 p.m. (New York City time), (b)  if the OTC Bulletin Board is not a Trading
Market, the volume weighted average price of the Common Stock for such date (or the nearest preceding date) on the OTC Bulletin
Board, (c) if the Common Stock is not then listed or quoted for trading on the OTC Bulletin Board and if prices for the Common
Stock are then reported in the “Pink Sheets” published by OTC Markets Group, Inc. (or a similar organization or agency
succeeding to its functions of reporting prices), the most recent bid price per share of the Common Stock so reported, or (d) in
all other cases, the fair market value of a share of Common Stock as determined by an independent appraiser selected in good faith
by the Holders of a majority in interest of the Warrants then outstanding and reasonably acceptable to the Company, the fees and
expenses of which shall be paid by the Company.

 

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“Trading
Day” means a day on which the principal Trading Market is open for trading.

 

“Trading
Market” means any of the following markets or exchanges on which the Common Stock is listed or quoted for trading on
the date in question: the NYSE MKT, the NASDAQ Capital Market, the NASDAQ Global Market, the NASDAQ Global Select Market, the New
York Stock Exchange, the OTC Bulletin Board or the OTC Markets Group, Inc. (or any successors to any of the foregoing).

 

d)          Mechanics
of Exercise.

 

i.            Delivery
of Warrant Shares Upon Exercise. The Company shall cause the Warrant Shares purchased hereunder to be transmitted by the Warrant
Agent to the Holder by crediting the account of the Holder’s prime broker with The Depository Trust Company (“DTC”)
through its Deposit/Withdrawal at Custodian (“DWAC”) system if the Company is then a participant in such system
and either (A) there is an effective Registration Statement permitting the issuance of the Warrant Shares to Holder or (B) this
Warrant is being exercised via Cashless Exercise, and otherwise by physical delivery to the address specified by the Holder in
the Notice of Exercise by the date that is three (3) Trading Days after (A) receipt by the Warrant Agent of the Notice of Exercise
and (B) receipt by the Warrant Agent of payment of the aggregate Exercise Price (such date, the “Warrant Share Delivery
Date”). This Warrant shall be deemed to have been exercised upon delivery of the Notice of Exercise and payment of the
Exercise Price to the Warrant Agent. The Warrant Shares shall be deemed to have been issued, and Holder or any other person so
designated to be named therein shall be deemed to have become a holder of record of such shares for all purposes, as of the date
the Warrant has been exercised. Notwithstanding anything else to the contrary in this Warrant, if the Holder fails to duly deliver
payment to the Warrant Agent of an amount equal to the aggregate Exercise Price of the Warrant Shares to be purchased upon exercise
of this Warrant by the applicable Price Delivery Date as set forth in Section 2(a) hereof, the Company will not obligated to deliver
or cause the Warrant Agent to deliver any such Warrant Shares (via DWAC or otherwise) until following receipt of such payment,
and the applicable Warrant Share Delivery Date shall be deemed extended by one day for each day (or part thereof) that after the
Price Delivery Date until such payment is delivered to the Warrant Agent.

 

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ii.         Delivery
of New Warrants Upon Exercise. If this Warrant shall have been exercised in part, the Company shall (or shall direct the Warrant
Agent to), at the request of a Holder and upon surrender of this Warrant, at the time of delivery of the Warrant Shares, deliver
to Holder a new Warrant evidencing the rights of Holder to purchase the unpurchased Warrant Shares called for by this Warrant,
which new Warrant shall in all other respects be identical with this Warrant.

 

iii.         Rescission
Rights. If the Company fails to cause the Warrant Agent to transmit to the Holder the Warrant Shares pursuant to Section 2(d)(i)
by the Warrant Share Delivery Date, then, the Holder will have the right to rescind such exercise.

 

iv.         Compensation
for Buy-In on Failure to Timely Deliver Warrant Shares Upon Exercise. In addition to any other rights available to the Holder,
if the Company fails to cause the Warrant Agent to transmit to the Holder the Warrant Shares pursuant to an exercise on or before
the Warrant Share Delivery Date, and if after such date the Holder is required by its broker to purchase (in an open market transaction
or otherwise) or the Holder’s brokerage firm otherwise purchases, shares of Common Stock to deliver in satisfaction of a
sale by the Holder of the Warrant Shares which the Holder anticipated receiving upon such exercise (a “Buy-In”),
then the Company shall (or shall direct the Warrant Agent to), within five (5) Trading Days after the Holder’s request, either
(A) pay in cash to the Holder the amount, if any, by which (x) the Holder’s total purchase price (including brokerage commissions,
if any) for the shares of Common Stock so purchased exceeds (y) the amount obtained by multiplying (1) the number of Warrant Shares
that the Company was required to deliver to the Holder in connection with the exercise at issue times (2) the price at which the
sell order giving rise to such purchase obligation was executed, and (B) at the option of Holder, either reinstate the portion
of the Warrant and equivalent number of Warrant Shares for which such exercise was not honored (in which case such exercise shall
be deemed rescinded) or deliver to Holder the number of shares of Common Stock that would have been issued had the Company timely
complied with its exercise and delivery obligations hereunder. For example, if the Holder purchases Common Stock having a total
purchase price of $11,000 to cover a Buy-In with respect to an attempted exercise of shares of Common Stock with an aggregate sale
price giving rise to such purchase obligation of $10,000, under clause (A) of the immediately preceding sentence the Company shall
be required to pay the Holder $1,000. The Holder shall provide the Company written notice indicating the amounts payable to the
Holder in respect of the Buy-In and, upon request of the Company, evidence of the amount of such loss.

 

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Notwithstanding
the forgoing, the Company shall not be required to make the payments set forth herein if the Holder fails to timely file request
with DTC to receive such Warrant Shares via the Deposit Withdrawal at Custodian system.

 

v.           No
Fractional Shares or Scrip. No fractional shares or scrip representing fractional shares shall be issued upon the exercise
of this Warrant. As to any fraction of a share which the Holder would otherwise be entitled to purchase upon such exercise, the
Company shall (or shall direct the Warrant Agent to), at its election, either pay a cash adjustment in respect of such final fraction
in an amount equal to such fraction multiplied by the Exercise Price or round (up or down) to the nearest whole share.

 

vi.         Charges,
Taxes and Expenses. Issuance of Warrant Shares shall be made without charge to the Holder for any issue or transfer tax or
other incidental expense in respect of the issuance of such Warrant Shares, all of which taxes and expenses shall be paid by the
Company, and such Warrant Shares shall be issued in the name of the Holder or in such name or names as may be directed by the Holder;
provided, however, that in the event Warrant Shares are to be issued in a name other than the name of the Holder,
this Warrant when surrendered for exercise shall be accompanied by the Assignment Form attached hereto duly executed by the Holder
and the Company or the Warrant Agent may require, as a condition thereto, the payment of a sum sufficient to reimburse it for any
transfer tax incidental thereto.

 

vii.         Closing
of Books. The Company will not close its stockholder books or records in any manner which prevents the timely exercise of this
Warrant, pursuant to the terms hereof.

 

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e)          Holder’s
Exercise Limitations. Notwithstanding anything to the contrary contained in this Warrant, this Warrant shall not be exercisable
by the Holder hereof to the extent (but only to the extent) that the Holder or any of its affiliates would beneficially own in
excess of 4.99% of the number of shares of the Common Stock outstanding immediately after giving effect to the issuance of shares
of Common Stock issuable upon exercise of this Warrant (the “Maximum Percentage”). For purposes of the foregoing
sentence, the number of shares of Common Stock beneficially owned by the Holder and its affiliates shall include the number of
Warrant Shares which are subject to the Notice of Exercise with respect to which such determination is being made, but shall exclude
the number of shares of Common Stock which are issuable upon (i) exercise of the remaining, unexercised portion of this Warrant
and beneficially owned by the Holder or any of its affiliates, and (ii) exercise or conversion of the unexercised or unconverted
portion of any other securities of the Company beneficially owned by the Holder or any of its affiliates that are subject to a
limitation on conversion or exercise similar to the limitation contained herein. To the extent the above limitation applies, the
determination of whether this Warrant shall be exercisable (vis-à-vis other convertible, exercisable or exchangeable securities
owned by the Holder or any of its affiliates) and of which such securities shall be exercisable (as among all such securities owned
by the Holder) shall, subject to such Maximum Percentage limitation, be determined by the Holder, and the Company shall have no
responsibility for determining the accuracy of the Holder’s determination. No prior inability to exercise this Warrant pursuant
to this paragraph shall have any effect on the applicability of the provisions of this paragraph with respect to any subsequent
determination of exercisability. For the purposes of this paragraph, beneficial ownership and all determinations and calculations
(including, without limitation, with respect to calculations of percentage ownership) shall be determined in accordance with Section
13(d) of the Exchange Act and the rules and regulations promulgated thereunder. The provisions of this paragraph shall be implemented
in a manner otherwise than in strict conformity with the terms of this paragraph to correct this paragraph (or any portion hereof)
which may be defective or inconsistent with the intended Maximum Percentage beneficial ownership limitation herein contained or
to make changes or supplements necessary or desirable to properly give effect to such Maximum Percentage limitation. The limitations
contained in this paragraph shall apply to a successor Holder of this Warrant. For any reason at any time, upon the written or
oral request of the Holder, the Company shall within two (2) Business Days confirm orally and in writing to the Holder the number
of shares of Common Stock then outstanding, including by virtue of any prior conversion or exercise of convertible or exercisable
securities into Common Stock, including, without limitation, pursuant to this Warrant.

 

Section 3.          Certain
Adjustments.

 

a)       Stock
Dividends and Splits. If the Company, at any time while this Warrant is outstanding: (i) pays a stock dividend or otherwise
makes a distribution or distributions on shares of its Common Stock or any other equity or equity equivalent securities payable
in shares of Common Stock (which, for avoidance of doubt, shall not include any shares of Common Stock issued by the Company upon
exercise of this Warrant), (ii) subdivides outstanding shares of Common Stock into a larger number of shares, (iii) combines (including
by way of reverse stock split) outstanding shares of Common Stock into a smaller number of shares, or (iv) issues by reclassification
of shares of the Common Stock any shares of capital stock of the Company (collectively with the actions described in (i), (ii),
(iii) and (iv), a “Share Reorganization”), then in each case the Exercise Price shall be multiplied by a fraction
of which the numerator shall be the number of shares of Common Stock (excluding treasury shares, if any) outstanding immediately
before such event and of which the denominator shall be the number of shares of Common Stock outstanding immediately after such
event, and the number of shares issuable upon exercise of this Warrant shall be proportionately adjusted such that the aggregate
Exercise Price of this Warrant shall remain unchanged. Any adjustment made pursuant to this Section 3(a) shall become effective
immediately after the record date for the determination of stockholders entitled to receive such dividend or distribution and shall
become effective immediately after the effective date in the case of a subdivision, combination or re-classification, but if the
Company shall legally abandon any such dividend, distribution, subdivision, combination or reclassification prior to effecting
such action, no adjustment shall be made pursuant to this Section 3(a) in respect of such action.

 

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b)        Subsequent
Equity Sales. If the Company at any time while this Warrant is outstanding, shall sell or grant any option to purchase, or
sell or grant any right to reprice, or otherwise dispose of or issue (or announce any offer, sale, grant or any option to purchase
or other disposition) any Common Stock or Common Stock Equivalents, at an effective price per share less than (i) the Fair Market
Price per share and (ii) the IPO Price per share (such issuances collectively, a “Dilutive Issuance”) (it being understood
and agreed that if the holder of the Common Stock or Common Stock Equivalents so issued shall at any time, whether by operation
of purchase price adjustments, reset provisions, floating conversion, exercise or exchange prices or otherwise, or due to warrants,
options or rights per share which are issued in connection with such issuance, be entitled to receive shares of Common Stock at
an effective price per share that is less than the Exercise Price, such issuance shall be deemed to have occurred for less than
the Exercise Price on such date of the Dilutive Issuance at such effective price), then in each case, the Exercise Price (abbreviated
as EP0 below) shall be reduced (and only reduced) based on the following formula:

 

EP’= EP0 * (OS + X) / (OS
+ Y) where:

 

EP’ = the reduced Exercise
Price in effect immediately on and after such Dilutive Issuance;

 

EP0 = the Exercise Price in effect
immediately prior to such issuance or sale;

 

OS = the number of shares of Common
Stock outstanding immediately before such Dilutive Issuance;

 

X = the number of shares of Common
Stock equal to the quotient of (A) the aggregate price payable in the Dilutive Issuance (i) in respect of such shares of Common
Stock issued or sold (in the case of an issuance or sale of Common Stock) or (ii) in respect of the shares of Common Stock issuable
upon exercise, conversion or exchange of the Common Stock Equivalents issued or sold (in the case of an issuance or sale of Common
Stock Equivalents) in the Dilutive Issuance divided by (B) the Fair Market Price immediately before such Dilutive Issuance; and

 

Y = (i) the total number of shares
of Common Stock issued (in the case of an issuance or sale of Common Stock) or (ii) the total number of shares of Common Stock
issuable upon exercise, conversion or exchange of Common Stock Equivalents issued or sold (in the case of an issuance or sale of
Common Stock Equivalents) in the Dilutive Issuance. 

 

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Such adjustment
shall be made whenever such Common Stock or Common Stock Equivalents are issued. Notwithstanding the foregoing, no adjustments
shall be made, paid or issued under this Section 3(b) in respect of an Exempt Issuance. The Company shall notify the Holder, in
writing, no later than the fifth Trading Day following the issuance or deemed issuance of any Common Stock or Common Stock Equivalents
subject to this Section 3(b), indicating therein the applicable issuance price, or applicable reset price, exchange price, conversion
price and other pricing terms (such notice, the “Dilutive Issuance Notice”); provided, however,
that no such notice will be required if the Company has publicly disclosed such Dilutive Issuance on a Current Report on Form 8-K
filed on EDGAR and clearly specified the reduced Exercise Price applicable to this Warrant as a result of such Dilutive Issuance.
For purposes of clarification, whether or not the Company provides a Dilutive Issuance Notice pursuant to this Section 3(b), upon
the occurrence of any Dilutive Issuance, the Holder is entitled to receive a number of Warrant Shares based upon the reduced Exercise
Price (as calculated only by using the above formula) regardless of whether the Holder accurately refers to the reduced Exercise
Price in the Notice of Exercise. “Exempt Issuance” means the issuance by the Company of (a) shares of Common
Stock, options or other equity based awards to employees, officers, consultants or directors of the Company pursuant to any stock
or option plan duly adopted for such purpose, by a majority of the non-employee members of the Board of Directors or a majority
of the members of a committee of non-employee directors established for such purpose, (b) securities upon the exercise or exchange
of or conversion of any securities issued hereunder and/or other securities exercisable or exchangeable for or convertible into
shares of Common Stock issued and outstanding on the Issue Date, provided that such securities have not been amended since the
Issue Date to increase the number of such securities or to decrease the exercise price, exchange price or conversion price of such
securities, (c) securities issued pursuant to acquisitions or strategic transactions (including, without limitation, sponsored
research, collaboration, licensing, development, distribution, marketing or similar arrangement or alliance) approved by a majority
of the disinterested directors of the Company, but shall not, for the purposes of this clause (c), include a transaction in which
the Company is issuing securities primarily for the purpose of raising capital or to an entity whose primary business is investing
in securities, or (d) securities issued or issuable to parties providing leases, credit lines or similar transactions pursuant
to debt financing or commercial arrangements approved by a majority of the disinterested directors of the Company. “IPO
Price” means the initial public offering price of the Company’s combination of one share of Common Stock and one
Series A Warrant. “Common Stock Equivalents” means any securities of the Company which would entitle the holder
thereof to acquire at any time Common Stock, including, without limitation, any debt, preferred stock, right, option, warrant or
other instrument that is at any time convertible into or exercisable or exchangeable for, or otherwise entitles the holder thereof
to receive, Common Stock. “Fair Market Price” means, for any date, the price determined by the first of the
following clauses that applies: (a) if the Common Stock is then listed or quoted on a Trading Market, the closing price of the
Common Stock for such date (or the nearest preceding date) on the Trading Market on which the Common Stock is then listed or quoted
as reported by Bloomberg L.P. (based on a Trading Day from 9:30 a.m. (New York City time) to 4:02 p.m. (New York City time), (b) 
if the OTC Bulletin Board is not a Trading Market, the closing price of the Common Stock for such date (or the nearest preceding
date) on the OTC Bulletin Board, (c) if the Common Stock is not then listed or quoted for trading on the OTC Bulletin Board and
if prices for the Common Stock are then reported in the “Pink Sheets” published by OTC Markets Group, Inc. (or a similar
organization or agency succeeding to its functions of reporting prices), the most recent bid price per share of the Common Stock
so reported, or (d) in all other cases, the fair market value of a share of Common Stock as determined by an independent appraiser
selected in good faith by the Holders of a majority in interest of the Warrants then outstanding and reasonably acceptable to the
Company, the fees and expenses of which shall be paid by the Company.

 

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c)        Intentionally
Omitted. 

 

d)        Fundamental
Transaction. If, at any time while this Warrant is outstanding, (i) the Company, directly or indirectly, in one or more related
transactions effects any merger or consolidation with or into another Person, (ii) the Company, directly or indirectly, effects
any sale, lease, license, assignment, transfer, conveyance or other disposition of all or substantially all of its assets in one
or a series of related transactions, (iii) any, direct or indirect, purchase offer, tender offer or exchange offer (whether by
the Company or another Person) is completed pursuant to which holders of Common Stock are permitted to sell, tender or exchange
their shares for other securities, cash or property and has been accepted by the holders of 50% or more of the outstanding Common
Stock, (iv) the Company, directly or indirectly, in one or more related transactions effects any reclassification, reorganization
or recapitalization of the Common Stock or any compulsory share exchange pursuant to which the Common Stock is effectively converted
into or exchanged for other securities, cash or property, (v) the Company, directly or indirectly, in one or more related transactions
consummates a stock or share purchase agreement or other business combination (including, without limitation, a reorganization,
recapitalization, spin-off or scheme of arrangement) with another Person whereby such other Person acquires more than 50% of the
outstanding shares of Common Stock (not including any shares of Common Stock held by the other Person or other Persons making or
party to, or associated or affiliated with the other Persons making or party to, such stock or share purchase agreement or other
business combination) (each a “Fundamental Transaction”), then, upon any subsequent exercise of this Warrant,
the Holder shall have the right to receive, for each Warrant Share that would have been issuable upon such exercise immediately
prior to the occurrence of such Fundamental Transaction (without regard to any limitation in Section 2(e) on the exercise of this
Warrant), the number of shares of Common Stock of the successor or acquiring corporation or of the Company, if it is the surviving
corporation, and any additional consideration (the “Alternate Consideration”) receivable as a result of such
Fundamental Transaction by a holder of the number of shares of Common Stock for which this Warrant is exercisable immediately prior
to such Fundamental Transaction (without regard to any limitation in Section 2(e) on the exercise of this Warrant). For purposes
of any such exercise, the determination of the Exercise Price shall be appropriately adjusted to apply to such Alternate Consideration
based on the amount of Alternate Consideration issuable in respect of one share of Common Stock in such Fundamental Transaction,
and the Company shall apportion the Exercise Price among the Alternate Consideration in a reasonable manner reflecting the relative
value of any different components of the Alternate Consideration. If holders of Common Stock are given any choice as to the securities,
cash or property to be received in a Fundamental Transaction, then the Holder shall be given the same choice as to the Alternate
Consideration it receives upon any exercise of this Warrant following such Fundamental Transaction. Any such payment of such amount
of such Alternative Consideration shall be made in the same form of consideration (whether securities, cash or property) as is
given to the holders of Common Stock in such Fundamental Transaction, and if multiple forms of consideration are given, the consideration
shall be paid to the Holder in the same proportion as such consideration is paid to the holders of Common Stock. The terms of any
agreement pursuant to which a Fundamental Transaction is effected shall include terms requiring any such successor or surviving
entity to comply with the provisions of this Section 3(c).

 

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e)        Calculations.
All calculations under this Section 3 shall be made to the nearest cent or the nearest whole share, as the case may be.
For purposes of this Section 3, any calculation of the number of shares of Common Stock deemed to be issued and outstanding as
of a given date shall not include treasury shares, if any. Notwithstanding anything to the contrary in this Section 3, no adjustment
in the Exercise Price shall be required unless such adjustment would require an increase or decrease of at least 1% in such price;
provided however, that any adjustments which by reason of the immediately preceding sentence are not required to
be made shall be carried forward and taken into account in any subsequent adjustment. In any case in which this Section 3 shall
require that an adjustment in the Exercise Price be made effective as of a record date for a specified event, if Holder exercises
this Warrant after such record date, the Company may elect to defer, until the occurrence of such event, the issuance of the shares
of Common Stock and other capital stock of the Company in excess of the shares of Common Stock and other capital stock of the Company,
if any, issuable upon such exercise on the basis of the Exercise Price in effect prior to such adjustment; provided, however,
that in such case the Company or the Warrant Agent shall deliver to Holder a due bill or other appropriate instrument evidencing
Holder’s right to receive such additional shares and/or other capital securities upon the occurrence of the event requiring
such adjustment.

 

f)         Notice
to Holder.

 

i.            Adjustment
to Exercise Price. Whenever the Exercise Price or number of Warrant Shares is adjusted pursuant to any provision of this Section
3, the Company shall (or cause the Warrant Agent to) promptly mail to the Holder a notice setting forth the Exercise Price and
number of Warrant Shares after such adjustment and setting forth a brief statement of the facts requiring such adjustment.

 

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ii.         Notice
to Allow Exercise by Holder. After the Issue Date and on or prior to the Termination Date, if (A) the Company shall declare
a dividend (or any other distribution in whatever form) on the Common Stock, (B) the Company shall declare a special nonrecurring
cash dividend on or a redemption of the Common Stock, (C) the Company shall authorize the granting to all holders of the Common
Stock rights or warrants to subscribe for or purchase any shares of capital stock of any class or of any rights, (D) the approval
of any stockholders of the Company shall be required in connection with any reclassification of the Common Stock, any consolidation
or merger to which the Company is a party, any sale or transfer of all or substantially all of the assets of the Company, or any
compulsory share exchange whereby the Common Stock is converted into other securities, cash or property, or (E) the Company shall
authorize the voluntary or involuntary dissolution, liquidation or winding up of the affairs of the Company, then, in each case,
the Company shall cause to be mailed to the Holder at its last address as it shall appear upon the Warrant Register, at least 20
calendar days prior to the applicable record or effective date hereinafter specified, a notice stating (x) the date on which a
record is to be taken for the purpose of such dividend, distribution, redemption, rights or warrants, or if a record is not to
be taken, the date as of which the holders of the Common Stock of record to be entitled to such dividend, distributions, redemption,
rights or warrants are to be determined or (y) the date on which such reclassification, consolidation, merger, sale, transfer or
share exchange is expected to become effective or close, and the date as of which it is expected that holders of the Common Stock
of record shall be entitled to exchange their shares of the Common Stock for securities, cash or other property deliverable upon
such reclassification, consolidation, merger, sale, transfer or share exchange; provided that the failure to mail such notice or
any defect therein or in the mailing thereof shall not affect the validity of the corporate action required to be specified in
such notice. To the extent that any notice provided hereunder constitutes, or contains, material, non-public information regarding
the Company, the Company shall simultaneously file such notice with the Commission pursuant to a Current Report on Form 8-K. The
Holder shall remain entitled to exercise this Warrant during the period commencing on the date of such notice to the effective
date of the event triggering such notice except as may otherwise be expressly set forth herein.

 

Section 4.            Transfer
of Warrant.

 

a)         Transferability.
Subject to compliance with any applicable securities laws, this Warrant and all rights hereunder are transferable, in whole or
in part, upon delivery of this Warrant (or delivery of the book-entry warrant certificate representing this Warrant) at the principal office of the Company or the Warrant Agent (or other designated agent),
together with a written assignment of this Warrant substantially in the form attached hereto duly executed by the Holder or its
agent or attorney and funds sufficient to pay any transfer taxes payable upon the making of such transfer. Upon such surrender
and, if required, such payment, the Company shall execute and deliver a new Warrant or Warrants in the name of the assignee or
assignees, as applicable, and in the denomination or denominations specified in such instrument of assignment, and shall issue
to the assignor a new Warrant evidencing the portion of this Warrant not so assigned, and this Warrant shall promptly be cancelled.
The Warrant, if properly assigned in accordance herewith, may be exercised by a new holder for the purchase of Warrant Shares without
having a new Warrant issued.

 

    	-11-

    	 

    

 

b)       New
Warrants. This Warrant may be divided or combined with other Warrants upon presentation hereof at the aforesaid office of the
Company or the Warrant Agent (or other designated agent), together with a written notice specifying the names and denominations
in which new Warrants are to be issued, signed by the Holder or its agent or attorney. Subject to compliance with Section 4(a),
as to any transfer which may be involved in such division or combination, the Company shall execute and deliver (or cause the Warrant
Agent to deliver) a new Warrant or Warrants in exchange for the Warrant or Warrants to be divided or combined in accordance with
such notice. All Warrants issued on transfers or exchanges shall be dated the initial issuance date set forth on the first page
of this Warrant and shall be identical with this Warrant except as to the number of Warrant Shares issuable pursuant thereto.

 

c)       Warrant
Register. This Warrant shall be issuable in book entry form (the “Book-Entry Warrant Certificate”) and shall
initially be represented by one or more Book-Entry Warrant Certificates deposited with the Warrant Agent and registered in the name of the Holder,
or as otherwise directed by the DTC. Ownership of beneficial interests in this Warrant shall be
shown on, and the transfer of such ownership shall be effected through, records maintained by the Warrant Agent (the “Warrant Register”).
The Company may deem and treat the registered Holder of this Warrant as the absolute owner hereof
for the purpose of any exercise hereof or any distribution to the Holder, and for all other purposes, absent actual written notice
to the contrary.

 

Section 5.         Miscellaneous.

 

a)       No
Rights as Stockholder Until Exercise. This Warrant does not entitle the Holder to any voting rights, dividends or other rights
as a stockholder of the Company prior to the exercise hereof as set forth in Section 2.

 

b)       Loss,
Theft, Destruction or Mutilation of Warrant. The Company covenants that upon receipt by the Company or the Warrant Agent of
evidence reasonably satisfactory to them of the loss, theft, destruction or mutilation of this Warrant or any stock certificate
relating to the Warrant Shares, and in case of loss, theft or destruction, of indemnity or security reasonably satisfactory to
it (including, posting a bond), and upon surrender and cancellation of such Warrant or stock certificate, if mutilated, the Company will make and deliver (or
cause the Warrant Agent to deliver) a new Warrant or stock certificate of like tenor and dated as of such cancellation, in lieu
of such Warrant or stock certificate.

 

    	-12-

    	 

    

 

c)        Saturdays,
Sundays, Holidays, etc. If the last or appointed day for the taking of any action or the expiration of any right required or
granted herein shall not be a Business Day, then, such action may be taken or such right may be exercised on the next succeeding
Business Day.

 

d)        Authorized
Shares.

 

The Company
covenants that, during the period the Warrant is outstanding, it will reserve from its authorized and unissued Common Stock a sufficient
number of shares to provide for the issuance of the Warrant Shares upon the exercise of any purchase rights under this Warrant
(without regard to any limitations on exercise contained herein). The Company further covenants that its issuance of this Warrant
shall constitute full authority to its officers who are charged with the duty of executing stock certificates to execute and issue
the necessary Warrant Shares upon the exercise of the purchase rights under this Warrant. The Company will take all such reasonable
action as may be necessary to assure that such Warrant Shares may be issued as provided herein without violation of any applicable
law or regulation, or of any requirements of the Trading Market upon which the Common Stock may be listed. The Company covenants
that all Warrant Shares which may be issued upon the exercise of the purchase rights represented by this Warrant will, upon exercise
of the purchase rights represented by this Warrant and payment for such Warrant Shares in accordance herewith, be duly authorized,
validly issued, fully paid and nonassessable and free from all taxes, liens and charges created by the Company in respect of the
issue thereof (other than taxes in respect of any transfer occurring contemporaneously with such issue).

 

Except and
to the extent as waived or consented to by the Holder, the Company shall not by any action, including, without limitation, amending
its certificate of incorporation or through any reorganization, transfer of assets, consolidation, merger, dissolution, issue or
sale of securities or any other voluntary action, avoid or seek to avoid the observance or performance of any of the terms of this
Warrant, but will at all times in good faith assist in the carrying out of all such terms and in the taking of all such actions
as may be necessary or appropriate to protect the rights of Holder as set forth in this Warrant against impairment. Without limiting
the generality of the foregoing, the Company will (i) not increase the par value of any Warrant Shares above the amount payable
therefor upon such exercise immediately prior to such increase in par value, (ii) take all such action as may be necessary or appropriate
in order that the Company may validly and legally issue fully paid and nonassessable Warrant Shares upon the exercise of this Warrant
and (iii) use commercially reasonable efforts to obtain all such authorizations, exemptions or consents from any public regulatory
body having jurisdiction thereof, as may be, necessary to enable the Company to perform its obligations under this Warrant.

 

Before taking
any action which would result in an adjustment in the number of Warrant Shares for which this Warrant is exercisable or in the
Exercise Price, the Company shall obtain all such authorizations or exemptions thereof, or consents thereto, as may be necessary
from any public regulatory body or bodies having jurisdiction thereof.

 

    	-13-

    	 

    

 

e)        Governing
Law. This Warrant shall be governed by, and construed in accordance with, the laws of the State of New York without giving
effect to the conflicts of law principles thereof.

 

f)         Nonwaiver
and Expenses. No course of dealing or any delay or failure to exercise any right hereunder on the part of Holder shall operate
as a waiver of such right or otherwise prejudice Holder’s rights, powers or remedies. Without limiting any other provision
of this Warrant, if the Company willfully and knowingly fails to comply with any provision of this Warrant, which results in any
material damages to the Holder, the Company shall pay to Holder such amounts as shall be sufficient to cover any costs and expenses
including, but not limited to, reasonable attorneys’ fees, including those of appellate proceedings, incurred by Holder in
collecting any amounts due pursuant hereto or in otherwise enforcing any of its rights, powers or remedies hereunder.

 

g)       Notices.
Any notice, request or other document required or permitted to be given or delivered to the Holder by the Company shall be delivered
in accordance with the notice provisions of the Warrant Agent Agreement.

 

h)       Limitation
of Liability. No provision hereof, in the absence of any affirmative action by Holder to exercise this Warrant to purchase
Warrant Shares, and no enumeration herein of the rights or privileges of Holder, shall give rise to any liability of Holder for
the purchase price of any Common Stock or as a stockholder of the Company, whether such liability is asserted by the Company or
by creditors of the Company.

 

i)         Remedies.
The Holder, in addition to being entitled to exercise all rights granted by law, including recovery of damages, will be entitled
to seek specific performance of its rights under this Warrant. The Company agrees that monetary damages may not be adequate compensation
for any loss incurred by reason of a breach by it of the provisions of this Warrant and hereby agrees to waive and not to assert
the defense in any action for specific performance that a remedy at law would be adequate.

 

j)         Successors
and Assigns. Subject to applicable securities laws, this Warrant and the rights and obligations evidenced hereby shall inure
to the benefit of and be binding upon the successors and permitted assigns of the Company and the successors and permitted assigns
of Holder. The provisions of this Warrant are intended to be for the benefit of any Holder from time to time of this Warrant and
shall be enforceable by the Holder or holder of Warrant Shares.

 

k)        Amendment.
This Warrant may be modified or amended or the provisions hereof waived with the written consent of the Company and the Holder.

 

l)         Severability.
Wherever possible, each provision of this Warrant shall be interpreted in such manner as to be effective and valid under applicable
law, but if any provision of this Warrant shall be prohibited by or invalid under applicable law, such provision shall be ineffective
to the extent of such prohibition or invalidity, without invalidating the remainder of such provisions or the remaining provisions
of this Warrant.

 

    	-14-

    	 

    

 

m)       Headings.
The headings used in this Warrant are for the convenience of reference only and shall not, for any purpose, be deemed a part of
this Warrant.

 

********************

(Signature Page Follows)

 

    	-15-

    	 

    

 

IN WITNESS WHEREOF, the
Company has caused this Warrant to be executed by its officer thereunto duly authorized as of the date first above indicated.

 

	 	RUTHIGEN, inc.
	 	 
	 	 
	 	By:	    
	 	 	 Name:
	 	 	Title: Chief Financial Officer

 

    	-16-

    	 

    

 

NOTICE OF EXERCISE

 

		To:	RUTHIGEN, inc.

 

(1)  The
undersigned hereby elects to purchase ________ Warrant Shares of the Company pursuant to the terms of the attached Warrant (only
if exercised in full), and tenders herewith payment of the exercise price in full, together with all applicable transfer taxes,
if any.

 

(2)  Payment
shall take the form of (check applicable box):

 

 ̈  in
lawful money of the United States; or

 

 ̈  (if
permitted) the cancellation of such number of Warrant Shares as is necessary, in accordance with the formula set forth in subsection
2(c), to exercise this Warrant with respect to the maximum number of Warrant Shares purchasable pursuant to the Cashless Exercise
procedure set forth in subsection 2(c).

 

(3)  Please
issue said Warrant Shares in the name of the undersigned or in such other name as is specified below:

 

	 	 	 	 
	 	 	 	 

 

The Warrant Shares shall be delivered to
the following DWAC Account Number or by physical delivery of a certificate to:

 

	 	 	 	 
	 	 	 	 
	 	 	 	 
	 	 	 	 
	 	 	 	 

 

[SIGNATURE
OF HOLDER]

 

Name of Investing Entity: __________________________________________________________________________

Signature of Authorized Signatory of
Investing Entity: ____________________________________________________

Name of Authorized Signatory: ______________________________________________________________________

Title of Authorized Signatory: _______________________________________________________________________

Date: __________________________________________________________________________________________

 

    	 

    	 

    

 

ASSIGNMENT FORM

 

(To assign the foregoing warrant, execute

this form and supply required information.

Do not use this form to exercise the warrant.)

 

FOR VALUE RECEIVED, [____]
all of or [_______] shares of the foregoing Warrant and all rights evidenced thereby are hereby assigned to

 

	_______________________________________________ whose address is

 

	_______________________________________________________________.
	 
	_______________________________________________________________
	 

 

	 	 	Dated:  ______________, _______	 
	 	 	 	 

 

	 	Holder’s Signature:		 
	 	 	 	 
	 	Holder’s Address:		 
	 	 	 	 
	 	 		 

 

NOTE: The signature to this Assignment
Form must correspond with the name as it appears on the face of the Warrant, without alteration or enlargement or any change whatsoever.Exhibit 4.5

 

                                                                                                                      

FORM OF WARRANT AGENT AGREEMENT

 

This Warrant Agent
Agreement made as of [___________], 2014, is between Ruthigen, a Delaware corporation, with offices at 2455 Bennett Valley Rd.,
Suite C116, Santa Rosa, California 95404 (the “Company”), and VStock Transfer, LLC, with offices at 77 Spruce
Street, Suite 201, Cedarhurst, New York (the “Warrant Agent”).

 

WHEREAS, the Company
has determined to issue and deliver to investors, among other securities, Series A Warrants (the “Series A Warrants”)
to purchase (1) up to [_________] shares of the Company’s common stock, par value $0.0001 per share (the “Common
Stock”) and (2) Series B Warrants to purchase up to [_________] shares of Common Stock (the “Series B Warrants,”
and collectively with the Series A Warrants, the “Warrants”), pursuant to an Underwriting Agreement entered
into between the Company and Dawson James Securities, Inc., as representative of the several Underwriters named on Schedule 1 attached
thereto, dated [___________], 2014 (the “Underwriting Agreement”). Each Series A Warrant evidencing the right
of the holder thereof to purchase, for an exercise price of $[___][100% of the IPO PRICE TO THE PUBLIC], one share of Common
Stock and Series B Warrant to purchase one share of Common Stock, for an exercise price of $[___][125% of the IPO PRICE TO THE
PUBLIC], subject to adjustment as described in the Warrants (each exercise price, as applicable, the “Warrant Price”);

 

WHEREAS, the Company
desires the Warrant Agent to act on behalf of the Company, and the Warrant Agent is willing to so act, in connection with the issuance,
registration, transfer, exchange, redemption and exercise of the Warrants;

 

WHEREAS, the Company
desires to provide for the form and provisions of the Warrants, the terms upon which they shall be issued and exercised, and the
respective rights, limitation of rights and immunities of the Company, the Warrant Agent and the holders of the Warrants; and

 

WHEREAS, all acts and
things have been done and performed which are necessary to make the Warrants, when executed on behalf of the Company and countersigned
by or on behalf of the Warrant Agent, as provided herein, the legally valid and binding obligations of the Company, and to authorize
the execution and delivery of this Warrant Agent Agreement.

 

NOW, THEREFORE, in
consideration of the mutual agreements herein contained, the parties hereto agree as follows:

 

 

    	1

    	 

    

 

1.                  
Appointment of Warrant Agent. The Company hereby appoints the Warrant Agent to act
as agent for the Company for the Warrants, and the Warrant Agent hereby accepts such appointment and agrees to perform the same
in accordance with the terms and conditions set forth in this Warrant Agent Agreement and each series of Warrant.

 

2.                  
Warrants.

 

2.1               
Form of Series A Warrant. Each Series A Warrant shall be (a) issued in book-entry
only, (b) in substantially the form of Exhibit A attached hereto, the provisions of which are incorporated herein, and (c)
signed by, or bear the facsimile signature of, the Chairman of the Board, the Chief Executive Officer of the Company or the Chief
Financial Officer of the Company. In the event the person whose facsimile signature has been placed upon any Series A Warrant shall
have ceased to serve in the capacity in which such person signed the Series A Warrant before such Warrant is issued, it may be
issued with the same effect as if he or she had not ceased to be such at the date of issuance.

 

2.2               
Form of Series B Warrant. Each Series B Warrant shall be (a) issued in book-entry
only, (b) in substantially the form of Exhibit B attached hereto, the provisions of which are incorporated herein, and (c)
signed by, or bear the facsimile signature of, the Chairman of the Board, the Chief Executive Officer of the Company or the Chief
Financial Officer of the Company. In the event the person whose facsimile signature has been placed upon any Series B Warrant shall
have ceased to serve in the capacity in which such person signed the Series B Warrant before such Warrant is issued, it may be
issued with the same effect as if he or she had not ceased to be such at the date of issuance.

 

2.3               
Registration. 

 

2.3.1          
Warrant Register. The Warrant Agent shall maintain books (“Warrant Register”),
for the registration of the original issuance and registration of transfers of the Warrants. Upon the initial issuance of the Warrants,
the Warrant Agent shall issue and register the Warrants in the names of the respective holders thereof in such denominations and
otherwise in accordance with instructions delivered to the Warrant Agent by the Company.

 

2.3.2          
Registered Holder. Prior to due presentment for registration of transfer of any Warrant,
the Company and the Warrant Agent may deem and treat the person in whose name such Warrant shall be registered in the Warrant Register
(“Registered Holder”), as the absolute owner of such Warrant and of each Warrant represented thereby (notwithstanding
any notation of ownership or other writing on the Book-Entry Warrant Certificate (as such term is defined below) made by anyone other than the Company or the Warrant Agent),
for the purpose of any exercise thereof, and for all other purposes, and neither the Company nor the Warrant Agent shall be affected
by any notice to the contrary.

 

2.3.3          
 The Warrants shall be issuable in book entry (the “Book-Entry Warrant Certificates”).
All of the Warrants shall initially be represented by one or more Book-Entry Warrant Certificates deposited with the Warrant Agent
and registered in the name of the Registered Holder. Ownership of beneficial interests in the Warrants shall be shown on, and the transfer
of such ownership shall be effected through, records maintained by the Warrant Agent.

 

    	2

    	 

    

 

3.                  
Exercise of Warrants. Subject to the provisions of the Warrants and this Warrant Agreement,
a Warrant, may be exercised by the Registered Holder thereof by delivering to the office of the Warrant Agent, or at the office
of its successor as Warrant Agent, the notice of exercise, as set forth in the Warrant, duly executed, and by paying in full, in
lawful money of the United States, in cash, by wire transfer, or cashier’s check drawn on a United States bank payable to
the order of the Company (or, if available, pursuant to the cashless exercise feature as set forth in such Warrant), the Warrant
Price for each full share of Common Stock as to which the Warrant is exercised and the issuance of the Common Stock by the Warrant
Agent as set forth in the applicable Warrant. In no event shall the Registered Holder of any Warrant be entitled to “net
cash settle” the Warrant. The Warrant Agent will transmit to the Company the funds received from the Registered Holders for
the exercise of the Warrants within two (2) business days following the acceptance of such funds. 

 

4.                  
Concerning the Warrant Agent and Other Matters. 

 

4.1               
Payment of Taxes. The Company will, from time to time, promptly pay all taxes and charges
that may be imposed upon the Company or the Warrant Agent in respect of the issuance or delivery of shares of Common Stock upon
the exercise of Warrants, but the Company shall not be obligated to pay any transfer taxes in respect of the Warrants or such shares.

 

4.2               
Resignation, Consolidation, or Merger of Warrant Agent.

 

4.2.1          
Appointment of Successor Warrant Agent. The Warrant Agent, or any successor to it hereafter
appointed, may resign its duties and be discharged from all further duties and liabilities hereunder after giving sixty (60) days’
notice in writing to the Company. If the office of the Warrant Agent becomes vacant by resignation or incapacity to act or otherwise,
the Company shall appoint, in writing, a successor Warrant Agent in place of the Warrant Agent. If the Company shall fail to make
such appointment within a period of 30 days after it has been notified in writing of such resignation or incapacity by the Warrant
Agent or by the holder of the Warrant (who shall, with such notice, submit his, her or its Warrant for inspection by the Company),
then the holder of any Warrant may apply to the Supreme Court of the State of New York for the County of New York for the appointment
of a successor Warrant Agent. Any successor Warrant Agent, whether appointed by the Company or by such court, shall be a corporation
organized and existing under the laws of the State of New York, in good standing and have its principal office in the Borough of
Manhattan, City and State of New York, and be authorized under such laws to exercise corporate trust powers and subject to supervision
or examination by federal or state authorities. After appointment, any successor Warrant Agent shall be vested with all the authority,
powers, rights, immunities, duties and obligations of its predecessor Warrant Agent with like effect as if originally named as
Warrant Agent hereunder, without any further act or deed; but, if for any reason it becomes necessary or appropriate, the predecessor
Warrant Agent shall execute and deliver, at the expense of the Company, an instrument transferring to such successor Warrant Agent
all the authority, powers, and rights of such predecessor Warrant Agent hereunder; and, upon request of any successor Warrant Agent,
the Company shall make, execute, acknowledge, and deliver any and all instruments in writing for more fully and effectually vesting
in and confirming to such successor Warrant Agent all such authority, powers, rights, immunities, duties and obligations.

 

 

    	3

    	 

    

 

4.2.2          
Notice of Successor Warrant Agent. In the event a successor Warrant Agent shall be
appointed, the Company shall give notice thereof to the predecessor Warrant Agent and the transfer agent for the Common Stock not
later than the effective date of any such appointment. 

 

4.2.3          
Merger or Consolidation of Warrant Agent. Any corporation into which the Warrant Agent
may be merged or with which it may be consolidated or any corporation resulting from any merger or consolidation to which the Warrant
Agent shall be a party shall be the successor Warrant Agent under this Warrant Agent Agreement without any further act on the part
of the Company.

 

4.3               
Fees and Expenses of Warrant Agent.

 

4.3.1          
Remuneration. The Company agrees to pay the Warrant Agent reasonable remuneration for
its services as Warrant Agent hereunder as set forth on Exhibit C hereto and will reimburse the Warrant Agent upon
demand for all actual and documented expenditures that the Warrant Agent may reasonably incur in the execution of its duties hereunder.

 

4.3.2          
Further Assurances. The Company agrees to perform, execute, acknowledge and deliver,
or cause to be performed, executed, acknowledged and delivered, all such further and other acts, instruments and assurances as
may reasonably be required by the Warrant Agent for the carrying out or performing of the provisions of this Warrant Agent Agreement.

 

4.4               
Liability of Warrant Agent.

 

4.4.1          
Reliance on Company Statement. Whenever, in the performance of its duties under this
Warrant Agent Agreement, the Warrant Agent shall deem it necessary or desirable that any fact or matter be proved or established
by the Company prior to taking or suffering any action hereunder, such fact or matter (unless other evidence in respect thereof
be herein specifically prescribed) may be deemed to be conclusively proved and established by a statement signed by the Chief Executive
Officer, Chief Financial Officer or Chairman of the Board of the Company and delivered to the Warrant Agent. The Warrant Agent
may rely upon such statement for any action taken or suffered in good faith by it pursuant to the provisions of this Warrant Agent
Agreement.

 

    	4

    	 

    

 

4.4.2          
Indemnity. The Warrant Agent shall be liable hereunder only for its own negligence,
willful misconduct or bad faith. The Company agrees to indemnify the Warrant Agent and save it harmless against any and all liabilities,
including judgments, costs and reasonable counsel fees, for anything done or omitted by the Warrant Agent in the execution of this
Warrant Agent Agreement, except as a result of the Warrant Agent’s negligence, willful misconduct or bad faith.

 

4.4.3          
Exclusions. The
Warrant Agent shall have no responsibility with respect to the validity of this Warrant Agent Agreement or with respect to the
validity or execution of any Warrant (except its countersignature thereof); nor shall it be responsible for any breach by the Company
of any covenant or condition contained in this Warrant Agent Agreement or in any Warrant; nor shall it be responsible to make any
adjustments required under the adjustment provisions contained in the Warrants or responsible for the manner, method or amount
of any such adjustment or the ascertaining of the existence of facts that would require any such adjustment; nor shall it, by any
act hereunder, be deemed to make any representation or warranty as to the authorization or reservation of any shares of Common
Stock to be issued pursuant to this Warrant Agent Agreement or any Warrant or as to whether any shares of Common Stock will, when
issued, be valid, fully paid and nonassessable.

 

4.5               
Acceptance of Agency. The Warrant Agent hereby accepts the agency established by this
Warrant Agent Agreement and agrees to perform the same upon the terms and conditions herein set forth and, among other things,
shall account promptly to the Company with respect to Warrants exercised and concurrently account for, and pay to the Company,
all moneys received by the Warrant Agent for the purchase of shares of the Company’s Common Stock through the exercise of
Warrants.

 

5.                  
Notices of Changes in Warrant. Upon every adjustment of the exercise price of a Warrant
or the number of shares issuable upon exercise of a Warrant, the Company shall give written notice thereof to the Warrant Agent,
which notice shall state the Warrant exercise price resulting from such adjustment and the increase or decrease, if any, in the
number of shares purchasable at such price upon the exercise of a Warrant, setting forth in reasonable detail the method of calculation
and the facts upon which such calculation is based. 

 

6.                  
Reservation of Common Stock. The Company shall at all times reserve and keep available
a number of its authorized but unissued shares of Common Stock that will be sufficient to permit the exercise in full of all outstanding
Warrants issued pursuant to this Warrant Agreement.

 

 

    	5

    	 

    

 

7.                  
Miscellaneous Provisions.

 

7.1               
Loss, Theft, Destruction or Mutilation of Warrant. Upon receipt by the Company or the
Warrant Agent of evidence reasonably satisfactory to them of the loss, theft, destruction or mutilation of the Warrants or any
stock certificate relating to shares underlying the Warrants, and in case of loss, theft or destruction, of indemnity or security
reasonably satisfactory to them (including, posting a bond), and upon surrender and cancellation of such Warrant or stock certificate,
if mutilated, the Warrant Agent will deliver a new Warrant or stock certificate of like tenor and dated as of such cancellation,
in lieu of such Warrant or stock certificate.

 

7.2               
Successors. All the covenants and provisions of this Warrant Agent Agreement by or
for the benefit of the Company or the Warrant Agent shall bind and inure to the benefit of their respective successors and assigns.

 

7.3               
Notices. Any notice, statement or demand authorized by this Warrant Agent Agreement
to be given or made by the Warrant Agent or by the holder of any Warrant to or on the Company shall be delivered by hand or sent
by registered or certified mail or overnight courier service, addressed (until another address is filed in writing by the Company
with the Warrant Agent) as follows:

 

Ruthigen, Inc.

2455 Bennett Valley Road, Suite C116

Santa Rosa, California 95404

Attn: Chief Executive Officer

 

with a copy in each case to:

 

Mintz, Levin, Cohn, Ferris, Glovsky
and Popeo, P.C.

666 Third Avenue

New York, NY 10017

Attn: Linda K. Rockett, Esq.

 

Any notice, statement or demand authorized
by this Warrant Agent Agreement to be given or made by the holder of any Warrant or by the Company to or on the Warrant Agent shall
be delivered by hand or sent by registered or certified mail or overnight courier service, addressed (until another address is
filed in writing by the Warrant Agent with the Company), as follows:

 

VStock Transfer, LLC

150 West 46th Street, 6th Floor

New York, NY 10036

Attn: Compliance Department

 

Any notice, statement or demand authorized
to be given or made by the Warrant Agent or the Company to the holder of any Warrant shall be delivered by hand or sent by registered
or certified mail or overnight courier service, addressed, at the last address set forth for such holder in the Warrant Register.

 

    	6

    	 

    

 

 

Any notice, sent pursuant to this Warrant
Agent Agreement shall be effective, if delivered by hand, upon receipt thereof by the party to whom it is addressed, if sent by
overnight courier, on the next business day of the delivery to the courier, and if sent by registered or certified mail on the
third day after registration or certification thereof.

 

7.4               
Applicable Law. The validity, interpretation, and performance of this Warrant Agent
Agreement and of the Warrants shall be governed in all respects by the laws of the State of New York, without giving effect to
conflict of laws. The Company hereby agrees that any action, proceeding or claim against it arising out of or relating in any way
to this Warrant Agent Agreement shall be brought and enforced in the courts of the State of New York or the United States District
Court for the Southern District of New York, and irrevocably submits to such jurisdiction, which jurisdiction shall be exclusive.
The Company hereby waives any objection to such exclusive jurisdiction and that such courts represent an inconvenient forum. Any
such process or summons to be served upon the Company may be served by transmitting a copy thereof by registered or certified mail,
return receipt requested, postage prepaid, addressed to it at the address set forth in Section 6.2 hereof. Such mailing shall be
deemed personal service and shall be legal and binding upon the Company in any action, proceeding or claim.

 

7.5               
Examination of the Warrant
Agreement. A copy of this Warrant Agent Agreement shall be available at all reasonable times at the office of the Warrant Agent
for inspection by the Registered Holder of any Warrant. The Warrant Agent may require any such holder to submit his, her or its
Warrant for inspection.

 

7.6               
Counterparts; Facsimile Signatures. This Warrant Agent Agreement may be executed in
any number of counterparts, and each of such counterparts shall, for all purposes, be deemed to be an original, and all such counterparts
shall together constitute one and the same instrument. Facsimile signatures shall constitute original signatures for all purposes
of this Warrant Agent Agreement.

 

7.7               
Effect of Headings. The section headings herein are for convenience only and are not
part of this Warrant Agent Agreement and shall not affect the interpretation thereof 

 

7.8               
Amendments.

 

7.8.1          
This Warrant Agent Agreement and any Warrant may be amended by the parties hereto
by executing a supplemental warrant agreement (a “Supplemental Agreement”), without the consent of any of the
Warrant holders, for the purpose of (i) curing any ambiguity, or curing, correcting or supplementing any defective provision contained
herein, or making any other provisions with respect to matters or questions arising under this Warrant Agent Agreement that is
not inconsistent with the provisions of this Warrant Agent Agreement or the Warrant, (ii) evidencing the succession
of another corporation to the Company and the assumption by any such successor of the covenants of the Company contained in this
Warrant Agent Agreement and the Warrants, (iii) evidencing and providing for the acceptance of appointment by a successor Warrant
Agent with respect to the Warrants, (iv) adding to the covenants of the Company for the benefit of the Holders or surrendering
any right or power conferred upon the Company under this Warrant Agent Agreement, or (v) amending this Warrant Agent Agreement
and the Warrants in any manner that the Company may deem to be necessary or desirable and that will not adversely affect the interests
of the Warrant holders in any material respect.

 

 

    	7

    	 

    

 

7.8.2          
The Company and the Warrant Agent may amend this Warrant Agent Agreement by executing a Supplemental
Agreement with the consent of the Holders of not fewer than a majority of the unexercised Warrants affected by such amendment,
for the purpose of adding any provisions to or changing in any manner or eliminating any of the provisions of this Warrant Agent
Agreement; provided, however, that, without the consent of each of the Warrant holders affected thereby, no such amendment may
be made that changes the Warrants.

 

7.9               
Severability. This Warrant Agent Agreement shall be deemed severable, and the invalidity
or unenforceability of any term or provision hereof shall not affect the validity or enforceability of this Warrant Agent Agreement
or of any other term or provision hereof. Furthermore, in lieu of any such invalid or unenforceable term or provision, the parties
hereto intend that there shall be added as a part of this Warrant Agent Agreement a provision as similar in terms to such invalid
or unenforceable provision as may be possible and be valid and enforceable.

 

    	8

    	 

    

 

IN WITNESS WHEREOF,
this Warrant Agent Agreement has been duly executed by the parties hereto as of the day and year first above written.

 

 

	 	RUTHIGEN, INC.

	 	 
	 	 
	 	By:	    
	 	 	[Name, Title]

	 	 
	 	 
	 	VSTOCK TRANSFER, LLC

	 	 
	 	 
	 	By:	    
	 	 	[Name, Title]

 

 

 

 

    	9

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