Document:

power3exhibit4

                             ARTICLES OF DESIGNATION

                                       of

                      SERIES B CONVERTIBLE PREFERRED STOCK

                                       of

                          POWER3 MEDICAL PRODUCTS, INC.

        POWER3 MEDICAL PRODUCTS, INC., a corporation organized and existing under
the laws of the State of New York (the "Corporation"), does hereby certify that,
pursuant to the authority conferred on its board of directors (the "Board of
Directors") by its articles of incorporation (the "Articles of Incorporation"),
as amended, and in accordance with Section 708 of the New York Business
Corporation Law, the Board of Directors (or, as to certain matters allowed by
law, a duly authorized committee thereof) adopted the following resolution
establishing a series of 3,000,000 shares of Preferred Stock of the Corporation
designated as "Series B Convertible Preferred Stock."

                RESOLVED, that pursuant to the authority conferred on the Board
        of Directors of this Corporation (the "Corporation") by the Articles
        of Incorporation, a series of Preferred Stock, $.001 par value, of the
        Corporation be and hereby is established and created, and that the
        designation and number of shares thereof and the voting and other
        powers, preferences and relative, participating, optional or other
        rights of the shares of such series and the qualifications,
        limitations and restrictions thereof are as follows:

                          Convertible Preferred Stock

        1. Designation and Amount. There shall be a series of Preferred Stock
designated as "Series B Convertible Preferred Stock," and the number of shares
constituting such series shall be 3,000,000. Such series is referred to herein
as the "Convertible Preferred Stock."

        2. Stated Capital. The amount to be represented in stated capital at all
times for each share of Convertible Preferred Stock shall be $.001.

        3. Rank. All shares of Convertible Preferred Stock shall rank pari passu
with all of the Corporation's Common Stock, par value $.001 per share (the
"Common Stock"), now or hereafter issued, as to distributions of assets upon
liquidation, dissolution or winding up of the Corporation, whether voluntary or
involuntary, but not as to payment of dividends.

        4. Dividends. No dividend shall be declared or paid on the Convertible
Preferred Stock.

        5. No Liquidation Preference. In the event of any voluntary or involuntary
liquidation, dissolution, or winding-up of the Corporation, after distribution
in full of the preferential amounts, if any, to be distributed to the holders of
shares of any series of preferred stock, having a priority on liquidation
superior to that of the Convertible Preferred Stock, the holders of shares of
Convertible Preferred Stock shall be entitled to participate with the Common
Stock in all of the remaining assets of the Corporation available for
distribution to its stockholders, ratably with the holders of Common Stock in
proportion to the number of shares of Common Stock held by them, assuming for
each holder of Convertible Preferred Stock on the record date for such
distribution that each holder was the holder of record of the number (including
any fraction) of shares of Common Stock into which the shares of Convertible
Preferred Stock then held by such holder are then convertible. A liquidation,
dissolution, or winding-up of the Corporation, as such terms are used in this
Section 5, shall not be deemed to be occasioned by or to include any merger of
the Corporation with or into one or more corporations or other entities, any
acquisition or exchange of the outstanding shares of one or more classes or
series of the Corporation, or any sale, lease, exchange, or other disposition of
all or a part of the assets of the Corporation.

                                       1

        6. Voting Rights. Except as otherwise required by law, the shares of
outstanding Convertible Preferred Stock shall have the number of votes equal to
the number of votes of all outstanding shares of Common Stock plus one
additional vote such that the holders of outstanding shares of Convertible
Preferred Stock shall always constitute a majority of the voting rights of the
Corporation. Except as otherwise required by law or by these Articles, the
holders of shares of Common Stock and Convertible Preferred Stock shall vote
together and not as separate classes.

        7. No Redemption. The shares of Convertible Preferred Stock are not
redeemable.

        8. Conversion Provisions.

                (a) For the purposes of this Section 8, the following definitions
        shall apply:

                        (i) "Common Stock" shall initially mean the class designated as
                Common Stock, par value $.001 per share, of the Corporation as of June
                15, 2004 subject to adjustment as hereinafter provided.

                        (ii) "Conversion Ratio" means the number of fully paid and
                nonassessable shares of Common Stock and such other securities and
                property as hereinafter provided, initially at the rate one share of
                Common Stock for each full share of Convertible Preferred Stock.

                        (iii) "Employee" means a person employed by the Corporation or by
                a legal entity (as defined in Subsection (ii) of this Section 8(a))
                that is controlled, directly or indirectly, by the Corporation;

                        (iv) "Legal Entity" means a corporation, partnership, joint
                venture, trust, employee benefit plan or other enterprise;

                        (v) "Transfer" means any sale, transfer, gift, assignment, devise
                or other disposition, whether directly or indirectly, voluntarily or
                involuntarily or by operation of law or otherwise; and

                        (vi) "Uncertificated Shares" means shares without certificates
                within the meaning of Section 78.235(4) of the New York Revised
                Statutes, as it may be amended from time to time, or any subsequent
                statute replacing this statute.

                (b) Without any action by the Corporation: (1) outstanding shares of
        Convertible Preferred Stock which are the subject of a Transfer shall be
        automatically converted into a number of shares of Common Stock determined by
        multiplying the Conversion Ratio then in effect by the number of shares
        Convertible Preferred Stock subject to the Transfer; and (2) in the event that
        an Employee ceases to be an Employee for any reason whatsoever, the outstanding
        shares of Convertible Preferred Stock held by such Employee shall be
        automatically converted into a number of shares of Common Stock determined by
        multiplying the Conversion Ratio then in effect by the number of shares
        Convertible Preferred Stock held by such Employee. For purposes of this Section
        8, the conversion of shares of Convertible Preferred Stock as a result of a
        Transfer and the conversion of shares of Convertible Preferred Stock as a result
        of cessation of an Employee's status as an Employee shall both be referred to as
        a "Conversion Event."

                        (i) A Conversion Event resulting from a Transfer shall be
                effective at such time as the holder of the Convertible Preferred
                Stock who is transferring such shares, regardless of the identity of
                the purchaser, transferee or other recipient, transfers such shares
                for disposition, at which time (the "Effective Time") the rights of
                the holder of the converted Convertible Preferred Stock as such holder
                shall cease and the holder of the converted Convertible Preferred
                Stock shall be deemed to have become the holder of record of the
                shares of Common Stock into which such shares of Convertible Preferred
                Stock have been converted as a result of the Transfer.

                        (ii) The Effective Time of a Conversion Event resulting from
                cessation of an Employee's status as an Employee shall be the day and
                time that the Employee's status as an Employee terminates. At the
                Effective Time the rights of the holder of the converted Convertible
                Preferred Stock as such holder shall cease and the holder of the

                                       2

                converted Convertible Preferred Stock shall be deemed to have become
                the holder of record of the shares of Common Stock into which such
                shares of Convertible Preferred Stock have been converted as a result
                of the Conversion Event.

                        (iii) Each conversion of shares of Convertible Preferred Stock
                into shares of Common Stock pursuant to this Section 8(b) shall be
                deemed to be effective upon the Effective Time and at the Effective
                Time the rights of the holder of the converted Convertible Preferred
                Stock as such holder shall cease and the holder of the converted
                Convertible Preferred Stock shall be deemed to have become the holder
                of record of the shares of Common Stock into which such shares of
                Convertible Preferred Stock have been converted as a result of the
                applicable Conversion Event.

                        (iv) The Board of Directors of the Corporation shall have the
                power to determine whether a Conversion Event has taken place with
                respect to any situation based upon the facts known to it. Each
                shareholder shall provide such information that the Corporation may
                reasonably request in order to ascertain facts or circumstances
                relating to a Transfer or proposed Transfer or a Conversion Event or
                proposed Conversion Event.

                (c) The holder of shares of Convertible Preferred Stock converted pursuant
        to this Section 8 shall promptly surrender the certificate or certificates
        representing the shares so converted at the principal office of the Corporation
        (or such other office or agency of the Corporation as the Corporation may
        designate by notice in writing to the holders of Convertible Preferred Stock) at
        any time during its usual business hours, and if such shares of Convertible
        Preferred Stock are Uncertificated Shares, shall promptly notify the Corporation
        in writing of such transfer at the principal office of the Corporation (or such
        other office or agency of the Corporation as the Corporation may designate by
        notice in writing to the holders of the Convertible Preferred Stock).

                (d) In no event shall the Corporation be liable to any such holder or any
        third party arising from any such conversion.

                (e) The shares of Common Stock resulting from a conversion of duly
        authorized, validly issued, fully paid and nonassessable shares of Convertible
        Preferred Stock into shares of Common Stock pursuant to this Section 8 shall be
        duly authorized, validly issued, fully paid and nonassessable. Any share of
        Convertible Preferred Stock which is converted into a share of Common Stock
        pursuant to this Section 8 shall become an authorized but unissued share of
        Convertible Preferred Stock.

                (f) The Corporation will at all times reserve and keep available out of its
        authorized but unissued shares of Common Stock solely for the purpose of issue
        upon conversion of Convertible Preferred Stock, such number of shares of Common
        Stock as shall then be issuable upon the conversion of all outstanding shares of
        Convertible Preferred Stock.

                (g) The issuance of certificates evidencing (or in the case of
        Uncertificated Shares, the provision of applicable written statements or other
        documents with respect to) shares of Common Stock upon conversion of shares of
        Convertible Preferred Stock shall be made without charge to the holders of such
        shares for any issue tax in respect thereof or other cost incurred by the
        Corporation in connection with such conversion; provided, however, the
        Corporation shall not be required to pay any tax that may be payable in respect
        of any Transfer involved in the issuance and delivery of any certificate in (or
        in the case of Uncertificated Shares, the provision of applicable written
        statements or other documents with respect to) a name other than that of the
        holder of the Convertible Preferred Stock converted.

                (h) The Conversion Ratio shall be subject to adjustment as follows:

                        (i) In case the Company shall (A) pay a dividend or make a
                distribution in Common Stock, or (B) subdivide or reclassify its
                outstanding shares of Common Stock into a greater or smaller number of
                shares, the Conversion Ratio in effect immediately prior thereto shall
                be adjusted retroactively as provided below so that the Conversion
                Ratio thereafter shall be determined by multiplying the Conversion
                Ratio at which such shares of Convertible Preferred Stock were
                theretofore convertible by a fraction of which the numerator shall be

                                       3

                the number of shares of Common Stock outstanding immediately following
                such action and of which the denominator shall be the number of shares
                of Common Stock outstanding immediately prior thereto. Such adjustment
                shall be made whenever any event described above shall occur and shall
                become effective retroactively immediately after the record date in
                the case of a dividend and shall become effective immediately after
                the effective date in the case of a subdivision or reclassification.

                        (ii) In case the Company shall issue rights or warrants to all
                holders of its Common Stock entitling them (for a period expiring
                within 45 days after the record date therefor) to subscribe for or
                purchase shares of Common Stock at a price per share less than the
                current market price per share of Common Stock (as determined in
                accordance with the provisions of Subsection (iv) of this Section 8)
                at the record date therefor (the "Current Market Price"), or in case
                the Company shall issue other securities convertible into or
                exchangeable for Common Stock for a consideration per share of Common
                Stock deliverable upon conversion or exchange thereof less than the
                Current Market Price; then the Conversion Ratio in effect immediately
                prior thereto shall be adjusted retroactively as provided below so
                that the Conversion Ratio therefor shall be equal to the price
                determined by multiplying the Conversion Ratio at which shares of
                Convertible Preferred Stock were theretofore convertible by a fraction
                of which the denominator shall be the number of shares of Common Stock
                outstanding on the date of issuance of such convertible or
                exchangeable securities, rights or warrants plus the number of
                additional shares of Common Stock offered for subscription or purchase
                and of which the numerator shall be the number of shares of Common
                Stock outstanding on the date of issuance of such shares, convertible
                or exchangeable securities, rights or warrants plus the number of
                additional shares of Common Stock which the aggregate offering price
                of the number of shares of Common Stock so offered would purchase at
                the Current Market Price per share of Common Stock (as determined in
                accordance with the provisions of Subsection (iv) of this Section 8.
                Such adjustment shall be made whenever such convertible or
                exchangeable securities rights or warrants are issued, and shall
                become effective retroactively immediately after the record date for
                the determination of stockholders entitled to receive such securities.
                However upon the expiration of any right or warrant to purchase Common
                Stock the issuance of which resulted in an adjustment in the
                Conversion Ratio pursuant to this Subsection (ii), if any such right
                or warrant shall expire and shall not have been exercised, the
                Conversion Ratio shall be recomputed immediately upon such expiration
                and effective immediately upon such expiration shall be increased to
                the price it would have been (but reflecting any other adjustments to
                the Conversion Ratio made pursuant to the provisions of this Section 8
                after the issuance of such rights or warrants) had the adjustment of
                the Conversion Ratio made upon the issuance of such rights or warrants
                been made on the basis of offering for subscription or purchase only
                that number of shares of Common Stock actually purchased upon the
                exercise of such rights or warrants actually exercised.

                        (iii) In case the Company shall distribute to all holders of its
                Common Stock (including any such distribution made in connection with
                a consolidation or merger in which the Company is the continuing
                corporation) shares of capital stock (other than Common Stock),
                evidences of its indebtedness or assets (excluding cash dividends) or
                rights to subscribe (excluding those referred to in Subsection (ii) of
                this Section 8), then in each such case the number of shares of Common
                Stock into which each share of Convertible Preferred Stock shall
                thereafter be convertible shall be determined by multiplying the
                number of shares of Common Stock into which such share of Convertible
                Preferred Stock was theretofore convertible by a fraction of which the
                numerator shall be the number of outstanding shares of Common Stock
                multiplied by the Current Market Price per share of Common Stock (as
                determined in accordance with the provisions of Subsection (iv) of
                this Section 8) on the date of such distribution and of which the
                denominator shall be the product of the number of outstanding shares
                of Common Stock and the Current Market Price per share of Common
                Stock, less the aggregate fair market value (as determined by the
                Board of Directors of the Company, whose determination shall be
                conclusive, and described in a statement filed with the transfer agent
                for the shares of Convertible Preferred Stock) of the capital stock,
                assets or evidences of indebtedness so distributed or of such
                subscription rights. Such adjustment shall be made whenever any such

                                       4

                distribution is made, and shall become effective retroactively
                immediately after the record date for the determination of
                stockholders entitled to receive such distribution.

                        (iv) For the purpose of any computation under Subsection (ii) and
                (iii) of this Section 8, the Current Market Price per share of Common
                Stock at any date shall be deemed to be the average Sale Price for the
                thirty consecutive trading days commencing forty-five trading days
                before the day in question. As used herein, "Sale Price" means the
                closing sales price of the Common Stock (or if no sale price is
                reported, the average of the high and low bid prices) as reported by
                the principal national or regional stock exchange on which the Common
                Stock is listed or, if the Common Stock is not listed on a national or
                regional stock exchange, as reported by national Association of
                Securities Dealers Automated Quotation System and if not so reported
                then as reported by the Electronic Bulletin Board or the National
                Quotation Bureau Incorporated.

                        (v) No adjustment in the Conversion Ratio shall be required
                unless such adjustment would require an increase or decrease of at
                least 1% in the price then in effect; provided, however, that any
                adjustments which by reason of this Subsection (v) are not required to
                be made shall be carried forward and taken into account in any
                subsequent adjustment. All calculations under this paragraph 8 shall
                be made to the nearest cent.

                        (vi) In the event that, at any time as a result of an adjustment
                made pursuant to Subsection (i) or Subsection (iii) of this Section 8,
                the holder of any share of Convertible Preferred Stock thereafter
                surrendered for conversion shall become entitled to receive any shares
                of the Company other than shares of the Common Stock, thereafter the
                number of such other shares so receivable upon conversion of any share
                of Convertible Preferred Stock shall be subject to adjustment from
                time to time in a manner and on the terms as nearly equivalent as
                practicable to the provisions with respect to the Common Stock
                contained in Subsections (i) through (v) of this Section 8, and the
                other provisions of this Subsection (vi) with respect to the Common
                Stock shall apply on like terms to any such other shares.

                        (vii) Whenever the conversion rate is adjusted, as herein
                provided, the Company shall promptly file with the transfer agent for
                Convertible Preferred Stock, a certificate of an officer of the
                Company setting forth the conversion rate after such adjustment and
                setting forth a brief statement of the facts requiring such adjustment
                and a computation thereof. Such certificate shall be conclusive
                evidence of the correctness of such adjustment. The Company shall
                promptly cause a notice of the adjusted conversion rate to be mailed
                to each registered holder of shares of Convertible Preferred Stock.

                (i) If any of the following events occur, namely (i) any reclassification
        or change (other than a combination of reclassification into a smaller number of
        shares) of outstanding shares of Common Stock issuable upon conversion of shares
        of Convertible Preferred Stock (other than a change in par value, or from par
        value to no par value, or from no par value to par value, or as a result of a
        subdivision) or (ii) any consolidation or merger to which the Company is a party
        (other than a consolidation or merger to which the Company is the continuing
        corporation and which does not result in any classification of, or change (other
        than a change in par value, or from par value to no par value, or from no par
        value to par value, or as a result of a subdivision) in, outstanding shares of
        Common Stock); then the Company or such successor, as the case may be, shall
        provide in its Certificate of Incorporation that each share of Convertible
        Preferred Stock shall be convertible into the kind and amount of shares of stock
        and other securities or property receivable upon such reclassification, change,
        consolidation or merger by a holder of the number of shares of Common Stock
        issuable upon conversion of each such share of Convertible Preferred Stock
        immediately prior to such reclassification, change, consolidation or merger.
        Such Certificate of Incorporation shall provide for adjustments which shall be
        as nearly equivalent as may be practicable to the adjustments provided for in
        Section 8. The Company shall cause notice of the execution of any such event
        contemplated by this paragraph to be mailed to each holder of shares of
        Convertible Preferred Stock as soon as practicable.

                                       5

                The above provisions of this Section 8(i) shall similarly apply to
        successive reclassifications, consolidations and mergers.

        9. Outstanding Shares. For purposes of these Articles of Designation, all
shares of Convertible Preferred Stock shall be deemed outstanding except (i)
from the date of surrender of certificates representing shares of Convertible
Preferred Stock, all shares of Convertible Preferred Stock converted into Common
Stock; and (ii) from the date of registration of transfer, all shares of
Convertible Preferred Stock held of record by the Corporation or any subsidiary
of the Corporation.

        10. The Securities Act of 1933

                (a) Securities Not Registered. Neither the shares of Convertible
        Preferred Stock nor the Common Stock issuable upon conversion thereof has
        been registered under the Securities Act of 1933 or the laws of any state
        of the United States and may not be transferred without such registration
        or an exemption from registration.

                (b) Restrictive Legends. Each share of Convertible Preferred Stock and
        certificate for Common Stock issued upon the conversion of any shares of
        Convertible Preferred Stock, and each preferred stock certificate issued
        upon the transfer of any such shares of Convertible Preferred Stock or
        Common Stock (except as otherwise permitted by this Section 11), shall be
        stamped or otherwise imprinted with a legend in substantially the following
        form:

                "The securities represented hereby have not been registered under
                the Securities Act of 1933. Such securities may not be sold or
                transferred in the absence of such registration or an exemption
                therefrom under said Act."

        11. Preemptive Rights. The Convertible Preferred is not entitled to any
preemptive or subscription rights in respect of any securities of the
Corporation.

        12. Severability of Provisions. Whenever possible, each provision hereof
shall be interpreted in a manner as to be effective and valid under applicable
law, but if any provision hereof is held to be prohibited by or invalid under
applicable law, such provision shall be ineffective only the extent of such
prohibition or invalidity, without invalidating or otherwise adversely affecting
the remaining provisions hereof. If a court of competent jurisdiction should
determine that a provision hereof would be valid or enforceable if a period of
time were extended or shortened or a particular percentage were increased or
decreased, then such court may make such change as shall be necessary to render
the provision in question effective and valid under applicable law.

        IN WITNESS WHEREOF, Power 3 Medical Products, Inc. has caused this
certificate to be signed by its President, and its corporate seal to be hereunto
affixed and attested by its Secretary, as of the 28th day of May, 2004.

                                    POWER 3 MEDICAL PRODUCTS, INC.

                                    By:/s/ Steven B. Rash
                                       Steven B. Rash, Chief Executive Officerpower3exhibit42

                              AMENDED AND RESTATED

                                   DESIGNATION

                                       of

                            SERIES A PREFERRED STOCK

                                       of

                         POWER 3 MEDICAL PRODUCTS, INC.

        I. The present name of the Corporation is Power 3 Medical Products, Inc.
(the "Corporation"). The original certificate of incorporation of the
Corporation was originally filed with the Secretary of State of the State of
Florida on December 23, 2003 under the name Surgical Products, Inc. On November
28, 1994, Surgical Products, Inc. merged into Sheffeld Acres, Inc., a New York
corporation and changed its name to Surgical Safety Products, Inc. Articles of
Merger were filed with the State of Florida on October 12, 1994 and a
Certificate of Merger was filed with the State of New York on February 8, 1995.
Surgical Safety Products, Inc. filed to do business as a foreign corporation on
April 11, 1995 in the State of Florida. On September 12, 2003, Surgical Safety
Products, Inc. changed its name to Power 3 Medical Products, Inc.

        II. This Amended and Restated Designation of Series A Preferred Stock
restates and amends the Designation filed with the Secretary of State of the
State of New York on May 1, 2003, was duly adopted in accordance with the
provisions of Section 708 of the New York Business Corporation Law.

        III. The text of the Designation of the Corporation is hereby amended and
restated to read in its entirety as follows:

                            SERIES A PREFERRED STOCK

        1. Designation and Amount. There shall be a series of Preferred Stock
designated as "Series A Convertible Preferred Stock," and the number of shares
constituting such series shall be 3,870,000. Such series is referred to herein
as the "Convertible Preferred Stock."

        2. Stated Capital. The amount to be represented in stated capital at all
times for each share of Convertible Preferred Stock shall be $.001.

        3. Rank. All shares of Convertible Preferred Stock shall rank prior to all
of the Corporation's Common Stock, par value $.001 per share (the "Common
Stock"), now or hereafter issued, both as to payment of dividends and as to
distributions of assets upon liquidation, dissolution or winding up of the
Corporation, whether voluntary or involuntary.

        4. Dividends. If any dividend or other distribution payable in cash,
securities or other property, including a dividend payable in shares of Common
Stock, is declared on the Common Stock, each holder of shares of Convertible
Preferred Stock on the record date for such dividend or distribution shall be
entitled to receive on the date of payment or distribution of such dividend or
other distribution the same cash, securities or other property which such holder
would have received on such record date if such holder was the holder of record
of the number (including any fraction) of shares of Common Stock into which the
shares of Convertible Preferred Stock then held by such holder are then
convertible. No dividend or other distribution shall be declared or paid on the
Common Stock unless an equivalent dividend or other distribution that satisfies
this Section 4 is declared or paid on the Convertible Preferred Stock.

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5. Liquidation Preference.

        (a) The liquidation value of shares of this Series, in case of the
voluntary or involuntary liquidation, dissolution or winding-up of the Company,
shall be $.10 per share, plus an amount equal to the dividends accrued and
unpaid thereon to the payment date.

        (b) In the event of any voluntary or involuntary liquidation, dissolution
or winding-up of the Company, the holders of shares of this Series (1) shall not
be entitled to receive the liquidation value of such shares held by them until
the liquidation value of all Preference Shares shall have been paid in full and
(2) shall be entitled to receive the liquidation value of such shares held by
them in preference to and in priority over any distributions upon the Common
Shares and all Junior Shares. Upon payment in full of the liquidation value to
which the holders of shares of this Series are entitled, the holders of shares
of this Series will not be entitled to any further participation in any
distribution of assets by the Company. If the assets of the Company are not
sufficient to pay in full the liquidation value payable to the holders of shares
of this Series and the liquidation value payable to the holders of all Parity
Shares, the holders of all such shares shall share ratably in such distribution
of assets in accordance with the amounts which would be payable on such
distribution if the amounts to which the holders of shares of this Series and
the holders of Parity Shares are entitled were paid in full.

        (c) Neither a consolidation or merger of the Company with or into any other
corporation, nor a merger of any other corporation with or into the Company, nor
a sale or transfer of all or any part of the Company's assets for cash or
securities or other property shall be considered a liquidation, dissolution or
winding-up of the Company within the meaning of this Paragraph 5.

        6. Voting Rights. Except as otherwise required by law, holders of
Convertible Preferred Stock are not entitled to vote.

        7. No Redemption. The shares of Convertible Preferred Stock are not
redeemable.

        8. Conversion Provisions.

                (a) Conversion at Option of Holders. Each share of Convertible Preferred
        Stock shall be convertible at the option of the holder thereof, at any time
        after October 31, 2004, into fully paid and nonassessable shares of Common Stock
        and such other securities and property as hereinafter provided, initially at the
        rate of .7752 shares of Common Stock for each full share of Convertible
        Preferred Stock ("Conversion Ratio").

                For the purpose of these Amended and Restated Designation, the term "Common
        Stock" shall initially mean the class designated as Common Stock, par value
        $.001 per share, of the Corporation as of May 5, 2004 subject to adjustment as
        hereinafter provided.

                (b) Mechanics of Conversion. Any holder of shares of Convertible Preferred
        Stock desiring to convert such shares into Common Stock shall surrender the
        certificate or certificates for such shares of Convertible Preferred Stock at
        the office of the transfer agent for the Convertible Preferred Stock, which
        certificate or certificates, if the Corporation shall so require, shall be duly
        endorsed to the Corporation or in blank, or accompanied by proper instruments of
        transfer to the Corporation or in blank, accompanied by irrevocable written
        notice to the Corporation that the holder elects so to convert such shares of
        Convertible Preferred Stock and specifying the name or names (with address) in
        which a certificate or certificates for Common Stock are to be issued.

                No adjustments in respect of any dividend on the Common Stock issued upon
        conversion shall be made upon the conversion of any shares of Convertible
        Preferred Stock.

                Any unpaid dividends on shares surrendered for conversion shall be paid
        upon the conversion of any shares of Convertible Preferred Stock by issuing
        additional shares of Common Stock with an aggregate value (as defined below)

                                       2

        equal to all accrued and unpaid dividends on the shares of Convertible Preferred
        Stock converted.

                The Corporation will, as soon as practicable after such deposit of
        certificates for Convertible Preferred Stock accompanied by the written notice
        and, compliance with any other conditions herein contained, deliver at the
        office of the transfer agent to the person for whose account such shares of
        Convertible Preferred Stock were so surrendered, or to his nominee or nominees,
        certificates for the number of full shares of Common Stock to which he shall be
        entitled as aforesaid, together with a cash adjustment of any fraction of a
        share as hereinafter provided. Subject to the following provisions of this
        paragraph, such conversion shall be deemed to have been made as of the date of
        such surrender of the shares of Convertible Preferred Stock to be converted, and
        the person or person entitled to receive the Common Stock deliverable upon
        conversion of such Convertible Preferred Stock shall be treated for all purposes
        as the record holder or holders of such Common Stock on such date; provided,
        however, that the Corporation shall not be required to convert any shares of
        Convertible Preferred Stock while the stock transfer books of the Corporation
        are closed for any purpose, but the surrender of Convertible Preferred Stock for
        conversion during any period while such books are so closed shall become
        effective for conversion immediately upon the reopening of such books as if the
        surrender had been made on the date of such reopening, and the conversion shall
        be at the conversion rate in effect on such date.

                (C) The Conversion Ratio shall be subject to adjustment as follows:

                        (i) In case the Company shall (A) pay a dividend or make a
                distribution in Common Stock, or (B) subdivide or reclassify its
                outstanding shares of Common Stock into a greater number (but not smaller
                number) of shares, the Conversion Ratio in effect immediately prior thereto
                shall be adjusted retroactively as provided below so that the Conversion
                Ratio thereafter shall be determined by multiplying the Conversion Ratio at
                which such shares of this Series were theretofore convertible by a fraction
                of which the numerator shall be the number of shares of Common Stock
                outstanding immediately following such action and of which the denominator
                shall be the number of shares of Common Stock outstanding immediately prior
                thereto. Such adjustment shall be made whenever any event listed above
                shall occur and shall become effective retroactively immediately after the
                record date in the case of a dividend and shall become effective
                immediately after the effective date in the case of a subdivision or
                reclassification.

                        (ii) In case the Company shall issue rights or warrants to all holders
                of its Common Stock entitling them (for a period expiring within 45 days
                after the record date therefor) to subscribe for or purchase shares of
                Common Stock at a price per share less than the current market price per
                share of Common Stock (as determined in accordance with the provisions of
                subclause (iv) of this clause (d)) at the record date therefor (the
                "Current Market Price"), or in case the Company shall issue other
                securities convertible into or exchangeable for Common Stock for a
                consideration per share of Common Stock deliverable upon conversion or
                exchange thereof less than the Current Market Price; then the Conversion
                Ratio in effect immediately prior thereto shall be adjusted retroactively
                as provided below so that the Conversion Ratio therefor shall be equal to
                the price determined by multiplying the Conversion Ratio at which shares of
                this Series were theretofore convertible by a fraction of which the
                denominator shall be the number of shares of Common Stock outstanding on
                the date of issuance of such convertible or exchangeable securities, rights
                or warrants plus the number of additional shares of Common Stock offered
                for subscription or purchase and of which the numerator shall be the number
                of shares of Common Stock outstanding on the date of issuance of such
                shares, convertible or exchangeable securities, rights or warrants plus the
                number of additional shares of Common Stock which the aggregate offering
                price of the number of shares of Common Stock so offered would purchase at
                the Current Market Price per share of Common Stock (as determined in
                accordance with the provisions of subclause (iv) of this clause (d). Such
                adjustment shall be made whenever such convertible or exchangeable
                securities rights or warrants are issued, and shall become effective
                retroactively immediately after the record date for the determination of
                stockholders entitled to receive such securities. However upon the
                expiration of any right or warrant to purchase Common Stock the issuance of
                which resulted in an adjustment in the Conversion Ratio pursuant to this
                subclause (ii), if any such right or warrant shall expire and shall not

                                       3

                have been exercised, the Conversion Ratio shall be recomputed immediately
                upon such expiration and effective immediately upon such expiration shall
                be increased to the price it would have been (but reflecting any other
                adjustments to the Conversion Ratio made pursuant to the provisions of this
                clause (d) after the issuance of such rights or warrants) had the
                adjustment of the Conversion Ratio made upon the issuance of such rights or
                warrants been made on the basis of offering for subscription or purchase
                only that number of shares of Common Stock actually purchased upon the
                exercise of such rights or warrants actually exercised.

                        (iii) In case the Company shall distribute to all holders of its
                Common Stock (including any such distribution made in connection with a
                consolidation or merger in which the Company is the continuing corporation)
                shares of capital stock (other than Common Stock), evidences of its
                indebtedness or assets (excluding cash dividends) or rights to subscribe
                (excluding those referred to in subclause (ii) of this clause (d)), then in
                each such case the number of shares of Common Stock into which each share
                of this Series shall thereafter be convertible shall be determined by
                multiplying the number of shares of Common Stock into which such share of
                this Series was theretofore convertible by a fraction of which the
                numerator shall be the number of outstanding shares of Common Stock
                multiplied by the Current Market Price per share of Common Stock (as
                determined in accordance with the provisions of subclause (iv) of this
                clause (d)) on the date of such distribution and of which the denominator
                shall be the product of the number of outstanding shares of Common Stock
                and the Current Market Price per share of Common Stock, less the aggregate
                fair market value (as determined by the Board of Directors of the Company,
                whose determination shall be conclusive, and described in a statement filed
                with the transfer agent for the shares of this Series) of the capital
                stock, assets or evidences of indebtedness so distributed or of such
                subscription rights. Such adjustment shall be made whenever any such
                distribution is made, and shall become effective retroactively immediately
                after the record date for the determination of stockholders entitled to
                receive such distribution.

                        (iv) For the purpose of any computation under subclause (ii) and (iii)
                of this clause (d), the Current Market Price per share of Common Stock at
                any date shall be deemed to be the average Sale Price for the thirty
                consecutive trading days commencing forty-five trading days before the day
                in question. As used herein, "Sale Price" means the closing sales price of
                the Common Stock (or if no sale price is reported, the average of the high
                and low bid prices) as reported by the principal national or regional stock
                exchange on which the Common Stock is listed or, if the Common Stock is not
                listed on a national or regional stock exchange, as reported by national
                Association of Securities Dealers Automated Quotation System and if not so
                reported then as reported by the Electronic Bulletin Board or the National
                Quotation Bureau Incorporated.

                        (v) No adjustment in the Conversion Ratio shall be required unless
                such adjustment would require an increase or decrease of at least 1% in the
                price then in effect; provided, however, that any adjustments which by
                reason of this subclause (v) are not required to be made shall be carried
                forward and taken into account in any subsequent adjustment. All
                calculations under this paragraph 8 shall be made to the nearest cent.

                        (vi) In the event that, at any time as a result of an adjustment made
                pursuant to subclause (i) or subclause (iii) of this clause (d), the holder
                of any share of this Series thereafter surrendered for conversion shall
                become entitled to receive any shares of the Company other than shares of
                the Common Stock, thereafter the number of such other shares so receivable
                upon conversion of any share of this Series shall be subject to adjustment
                from time to time in a manner and on the terms as nearly equivalent as
                practicable to the provisions with respect to the Common Stock contained in
                subclauses (i) through (v) of this clause (d), and the other provisions of
                this clause (d) with respect to the Common Stock shall apply on like terms
                to any such other shares.

                        (vii) Whenever the conversion rate is adjusted, as herein provided,
                the Company shall promptly file with the transfer agent for this Series, a
                certificate of an officer of the Company setting forth the conversion rate
                after such adjustment and setting forth a brief statement of the facts
                requiring such adjustment and a computation thereof. Such certificate shall

                                       4

                be conclusive evidence of the correctness of such adjustment. The Company
                shall promptly cause a notice of the adjusted conversion rate to be mailed
                to each registered holder of shares of this Series.

                (d) If any of the following events occur, namely (i) any reclassification
        or change (other than a combination of reclassification into a smaller number of
        shares) of outstanding shares of Common Stock issuable upon conversion of shares
        of this Series (other than a change in par value, or from par value to no par
        value, or from no par value to par value, or as a result of a subdivision) or
        (ii) any consolidation or merger to which the Company is a party (other than a
        consolidation or merger to which the Company is the continuing corporation and
        which does not result in any classification of, or change (other than a change
        in par value, or from par value to no par value, or from no par value to par
        value, or as a result of a subdivision) in, outstanding shares of Common Stock);
        then the Company or such successor, as the case may be, shall provide in its
        Certificate of Incorporation that each share of this Series shall be convertible
        into the kind and amount of shares of stock and other securities or property
        receivable upon such reclassification, change, consolidation or merger by a
        holder of the number of shares of Common Stock issuable upon conversion of each
        such share of this Series immediately prior to such reclassification, change,
        consolidation or merger. Such Certificate of Incorporation shall provide for
        adjustments which shall be as nearly equivalent as may be practicable to the
        adjustments provided for in clause (d). The Company shall cause notice of the
        execution of any such event contemplated by this paragraph to be mailed to each
        holder of shares of this Series as soon as practicable.

                The above provisions of this clause (e) shall similarly apply to successive
        reclassifications, consolidations and mergers.

        9. Protective Provisions.

                (a) Reservation of Shares; Transfer Taxes; Etc. The Corporation shall at
        all times serve and keep available, out of its authorized and unissued stock,
        solely for the purpose of effecting the conversion of the Convertible Preferred
        Stock, such number of shares of its Common Stock free of preemptive rights as
        shall from time to time be sufficient to effect the conversion of all shares of
        Convertible Preferred Stock from time to time outstanding. The Corporation shall
        from time to time, in accordance with the laws of the State of New York,
        increase the authorized number of shares of Common Stock if at any time the
        number of shares of Common Stock not outstanding shall not be sufficient to
        permit the conversion of all the then outstanding shares of Convertible
        Preferred Stock.

                If any shares of Common Stock required to be reserved for purposes of
        conversion of the Convertible Preferred Stock hereunder require registration
        with or approval of any governmental authority under any Federal or State law
        before such shares may be issued upon conversion, the Corporation will in good
        faith and as expeditiously as possible endeavor to cause such shares to be duly
        registered or approved, as the case may be. If the Common Stock is listed on the
        New York Stock Exchange or any other national securities exchange, the
        Corporation will, if permitted by the rules of such exchange, list and keep
        listed on such exchange, upon official notice of issuance, all shares of Common
        Stock issuable upon conversion of the Convertible Preferred Stock.

                The Corporation will pay any and all issue or other taxes that may be
        payable in respect of any issue or delivery of shares of Common Stock on
        conversion of the Convertible Preferred Stock. The Corporation shall not,
        however, be required to pay any tax which may be payable in respect of any
        transfer involved in the issue or delivery of Common Stock (or other securities
        or assets) in a name other than that which the shares of Convertible Preferred
        Stock so converted were registered, and no such issue or delivery shall be made
        unless and until the person requesting such issue has paid to the Corporation
        the amount of such tax or has established, to the satisfaction of the
        Corporation, that such tax has been paid.

                Prior Notice of Certain Events. In case:

                        (i) The Corporation shall (1) declare any dividend (or any other
                distribution) on its Common Stock, other than (A) a dividend payable in

                                       5

                shares of Common Stock or (B) a dividend payable in cash out of its
                retained earnings other than any special or nonrecurring or other
                extraordinary dividend or (2) declare or authorize a redemption or
                repurchase of in excess of 10% of the than-outstanding shares of Common
                Stock; or

                        (ii) the Corporation shall authorize the granting to the holders of
                Common Stock of rights or warrants to subscribe for or purchase any shares
                of stock of any class or of any other rights or warrants (other than any
                rights specified in subclause (ii) of clause (d) of this paragraph 9); or

                        (iii) of any reclassification of Common Stock (other than a
                subdivision of the outstanding Common Stock, or a change in par value, or
                from par value to no par value, or from no par value to par value), or of
                any consolidation or merger to which the Corporation is a party and for
                which approval of any stockholders of the Corporation shall be required, or
                of the sale or transfer of all or substantially all of the assets of the
                Corporation or of any compulsory share exchange whereby the Common Stock is
                converted into other securities, cash or other property; or

                        (iv) of the voluntary or involuntary dissolution, liquidation or
                winding up of the Corporation;

        then the Corporation shall cause to be filed with the transfer agent for the
        Convertible Preferred Stock, and shall cause to be mailed to the holders of
        record of the Convertible Preferred Stock, at their last address as they shall
        appear upon the stock transfer books of the Corporation, at least 15 days prior
        to the applicable record date hereinafter specified, a notice stating (x) the
        date on which a record is to be taken for the purpose of such dividend,
        distribution, redemption or granting of rights or warrants or, if a record is
        not to be taken, the date as of which the holders of Common Stock of record to
        be entitled to such dividend, distribution, redemption, rights or warrants are
        to be determined, or (y) the date on which such reclassification, consolidation,
        merger, sale, transfer, share exchange, dissolution, liquidation or winding up
        is expected to become effective, and the date as of which it is expected that
        holders of Common Stock of record shall be entitled to exchange their shares of
        Common Stock for securities or other property deliverable upon such
        reclassification, consolidation, merger, sale, transfer, share exchange,
        dissolution, liquidation or winding up (but no failure to mail such notice or
        any defect therein or in the mailing thereof shall affect the validity of the
        corporate action required to be specified in such notice).

                (c) Class Voting Rights. So long as the Convertible Preferred Stock is
        outstanding, the Corporation shall not, without the affirmative vote or consent
        of the holders of at least a majority of all outstanding Convertible Preferred
        Stock voting separately as a class, (i) Amend, alter or repeal (by merger or
        otherwise) any provision of the Articles of Incorporation or the By-Laws of the
        Corporation, as amended, so as adversely to affect the relative rights,
        preferences, qualifications, limitations or restrictions of the Convertible
        Preferred Stock, (ii) authorize or issue, or increase the authorized amount of,
        any additional class or series of stock, or any security convertible into stock
        of such class or series, ranking prior to the Convertible Preferred Stock in
        respect of the payment of dividends or upon liquidation, dissolution or winding
        up of the Corporation or (iii) effect any reclassification of the Convertible
        Preferred Stock. A class vote on the part of the Convertible Preferred Stock
        shall, without limitation, specifically not be deemed to be required (except as
        otherwise required by law or resolution of the Corporation's Board of Directors)
        in connection with: (a) the authorization, issuance or increase in the
        authorized amount of any shares of any other class or series of stock which
        ranks junior to, or on a parity with, the Convertible Preferred Stock in respect
        of the payment of dividends and distributions upon liquidation, dissolution or
        winding up of the Corporation; or (b) the authorization, issuance or increase in
        the amount of any bonds, mortgages, debentures or other obligations of the
        Corporation.

                The affirmative vote or consent of the holders of a majority of the
        outstanding Convertible Preferred Stock, voting or consenting separately as a
        class, shall be required to (a) authorize any sale, lease or conveyance of all
        or substantially all of the assets of the Corporation, or (b) approve any
        merger, consolidation or compulsory share exchange of the Corporation with or
        into any other person unless (i) the terms of such merger, consolidation or
        compulsory share exchange do not provide for a change in the terms of the
        Convertible Preferred Stock and (ii) the Convertible Preferred Stock is, after
        such merger, consolidation or compulsory share exchange on a parity with or
        prior to any other class or series of capital stock authorized by the surviving

                                       6

        corporation as to dividends and upon liquidation, dissolution or winding up
        other than any class or series of stock of the Corporation prior to the
        Convertible Preferred Stock as may have been created with the affirmative vote
        or consent of the holders of at least 66-2/3% of the Convertible Preferred Stock
        (or other than a class or series into which such prior stock is converted as a
        result of such merger, consolidation or share exchange).

        10. Outstanding Shares. For purposes of this Certificate of Designation,
all shares of Convertible Preferred Stock shall be deemed outstanding except (i)
from the date of surrender of certificates representing shares of Convertible
Preferred Stock, all shares of Convertible Preferred Stock converted into Common
Stock; (ii) from the date of registration of transfer, all shares of Convertible
Preferred Stock held of record by the Corporation or any subsidiary of the
Corporation.

        11. Certain Definitions. As used in this Certificate, the following terms
shall have the following respective meanings:

        "Affiliate" of any specified person means any other person directly or
indirectly controlling or controlled by or under common control with such
specified person. For purposes of this definition, "control" when used with
respect to any person means the power to direct the management and policies of
such person, directly or indirectly, whether through the ownership of voting
securities or otherwise; and the term "controlling" and "controlled" having
meanings correlative to the foregoing.

        "Common Shares" shall mean any stock of the Company which has no preference
in respect of dividends or of amounts payable in the event of any voluntary or
involuntary liquidation, dissolution or winding-up of the Company and which is
not subject to redemption by the Company. However, Common Shares issuable upon
conversion of shares of this series shall include only shares of the class
designated as common Shares as of the original date of issuance of shares of
this Series, or shares f the Company of any class or classes resulting from any
reclassification or reclassifications thereof and which have no preference in
respect of dividends or of amounts payable in the event of any voluntary or
involuntary liquidation, dissolution or winding-up of the Company and which are
not subject to redemption by the Company; provided that if at any time there
shall be more than one such resulting class, the shares of each such class then
so issuable shall be substantially in the proportion which the total number of
shares of such class resulting from such reclassifications bears to the total
number of shares of all classes resulting from all such reclassifications.

        "Junior Shares" shall mean Preference Shares of any series or class of the
Company which are by their terms expressly made junior to shares of this Series
at the time outstanding either as to dividends or as to the distribution of
assets on any voluntary or involuntary liquidation of the Company.

        "Parity Shares" shall mean Preference Shares which are by their terms on a
parity with the shares of this Series at the time outstanding both as to
dividends and as to the distribution of assets on any voluntary or involuntary
liquidation of the Company. For purposes of this paragraph 11 Parity Shares
shall mean Preference Shares which are by their terms on a parity with the
shares of this Series at the time outstanding as to dividends regardless of such
Preference Shares preference with respect to liquidation.

        "Senior Shares" shall mean any class of shares of the Company ranking prior
to at least one other class of shares of the Company as to dividends for
purposes of paragraph 4 and the distribution of assets on any voluntary or
involuntary liquidation of the Company for purposes of paragraph 5.

        13. Securities Not Registered Under the Securities Act of 1933. Neither the
shares of Convertible Preferred Stock nor the Common Stock issuable upon
conversion thereof has been registered under the Securities Act of 1933 or the
laws of any state of the United States and may not be transferred without such
registration or an exemption from registration.

                (a) Restrictive Legends. Each share of Convertible Preferred Stock and
        certificate for Common Stock issued upon the conversion of any shares of
        Convertible Preferred Stock, and each preferred stock certificate issued

                                       7

        upon the transfer of any such shares of Convertible Preferred Stock or
        Common Stock (except as otherwise permitted by this Section 12), shall be
        stamped or otherwise imprinted with a legend in substantially the following
        form:

                "The securities represented hereby have not been registered under the
                Securities Act of 1933. Such securities may not be sold or transferred
                in the absence of such registration or an exemption therefrom under
                said Act."

                (b) Notice of Proposed Transfer; Opinions of Counsel. Except as
        provided in paragraph (c) of this Section 11, prior to any transfer of any
        such shares of Convertible Preferred Stock, or Common Stock, the holder
        thereof will give written notice to the Corporation of such holder's
        intention to effect such transfer and to comply in all other respects with
        this Section 11. Each such notice (A) shall describe the manner and
        circumstances of the proposed transfer in sufficient detail to enable
        counsel to render the opinions referred to below, and (B) shall designate
        counsel for the holder giving such notice (who may be house counsel for
        such holder). The holder giving such notice will submit a copy thereof to
        the counsel designated in such notice and the Corporation will promptly
        submit a copy thereof to its counsel, and the following provisions shall
        apply:

                        (i) If in the opinion of each such counsel the proposed transfer
                of such shares of Convertible Preferred Stock or Common Stock may be
                effected without registration under the Act, the Corporation will
                promptly notify the holder thereof and such holder shall thereupon be
                entitled to transfer such shares of Convertible Preferred Stock or
                Common Stock in accordance with the terms of the notice delivered by
                such holder to the Corporation. Each share of Convertible Preferred
                Stock or certificate, if any, issued upon or in connection with such
                transfer shall bear the appropriate restrictive legend set forth in
                paragraph (a) of this Section 11, unless in the opinion of each such
                counsel such legend is no longer required to insure compliance with
                the Act. If for any reason counsel for the Corporation (after having
                been furnished with the information required to be furnished by this
                paragraph (b)) shall fail to deliver an opinion of the Corporation, or
                the Corporation shall fail to notify such holder thereof as aforesaid,
                within 20 days after counsel for such holder shall have delivered its
                opinion to such holder (with a copy to the Corporation), then for all
                purposes of this Certificate of Designation the opinion of counsel for
                the Corporation shall be deemed to be the same as the opinion of
                counsel for such holder.

                        (ii) If in the opinion of either or both of such counsel the
                proposed transfer of such shares of Convertible Preferred Stock or
                Common Stock may not be effected without registration under the Act,
                the Corporation will promptly so notify the holder thereof and
                thereafter such holder shall not be entitled to transfer such share of
                Convertible Preferred Stock or Common Stock until receipt of a further
                notice from the Corporation under subclause (i) above or, in the case
                of Common Stock, until registration of such Common stock under the Act
                has become effective.

        14. Preemptive Rights. The Convertible Preferred is not entitled to any
preemptive or subscription rights in respect of any securities of the
Corporation.

        15. Severability of Provisions. Whenever possible, each provision hereof
shall be interpreted in a manner as to be effective and valid under applicable
law, but if any provision hereof is held to be prohibited by or invalid under
applicable law, such provision shall be ineffective only the extent of such
prohibition or invalidity, without invalidating or otherwise adversely affecting
the remaining provisions hereof. If a court of competent jurisdiction should
determine that a provision hereof would be valid or enforceable if a period of
time were extended or shortened or a particular percentage were increased or
decreased, then such court may make such change as shall be necessary to render
the provision in question effective and valid under applicable law.

                                       8

        IN WITNESS WHEREOF, Power 3 Medical Products, Inc. has caused this
certificate to be signed by its President, and its corporate seal to be hereunto
affixed and attested by its Secretary, as of the 18th day of May, 2004.

                                 POWER 3 MEDICAL PRODUCTS, INC.

                                 By: /s/ Tim Novak, Chief Executive Officer

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