Document:

Exhibit 4.2

Exhibit 4.2

DUKE ENERGY CORPORATION

TO

THE BANK OF NEW YORK TRUST COMPANY, N.A.

Trustee

 

First Supplemental Indenture

Dated as of June 16, 2008

 

$250,000,000 5.65% SENIOR NOTES DUE 2013

$250,000,000 6.25% SENIOR NOTES DUE 2018

 

 

TABLE OF CONTENTS1

	 	 	 	 	 
	 	 	Page
	 
	 	 	 	 
	ARTICLE 1
	 	 	 	 
	5.65% SENIOR NOTES DUE 2013
	 	 	1	 
	 
	 	 	 	 
	Section 1.01. Establishment
	 	 	1	 
	Section 1.02. Definitions
	 	 	2	 
	Section 1.03. Payment of Principal and Interest
	 	 	2	 
	Section 1.04. Denominations
	 	 	3	 
	Section 1.05. Global Securities
	 	 	3	 
	Section 1.06. Redemption
	 	 	4	 
	Section 1.07. Paying Agent
	 	 	5	 
	 
	 	 	 	 
	ARTICLE 2
	 	 	 	 
	 
	 	 	 	 
	6.25% SENIOR NOTES DUE 2018
	 	 	5	 
	 
	 	 	 	 
	Section 2.01. Establishment
	 	 	5	 
	Section 2.02. Definitions
	 	 	6	 
	Section 2.03. Payment of Principal and Interest
	 	 	6	 
	Section 2.04. Denominations
	 	 	7	 
	Section 2.05. Global Securities
	 	 	7	 
	Section 2.06. Redemption
	 	 	7	 
	Section 2.07. Paying Agent
	 	 	9	 
	 
	 	 	 	 
	ARTICLE 3
	 	 	 	 
	 
	 	 	 	 
	MISCELLANEOUS PROVISIONS
	 	 	9	 
	 
	 	 	 	 
	Section 3.01. Recitals by the Corporation
	 	 	9	 
	Section 3.02. Ratification and Incorporation of Original Indenture
	 	 	9	 
	Section 3.03. Executed in Counterparts
	 	 	9	 
	 
	 	 	 	 
	Exhibit A —  Form of 5.65% Senior Note Due 2013
	 	 	 	 
	Exhibit B —  Certificate of Authentication
	 	 	 	 
	Exhibit C —  Form of 6.25% Senior Note Due 2018
	 	 	 	 
	Exhibit D —  Certificate of Authentication
	 	 	 	 

 

			
	1	 	This Table of Contents does not constitute part of the
Indenture or have any bearing upon the interpretation of any of its terms and
provisions.

-i-

 

     THIS FIRST SUPPLEMENTAL INDENTURE is made as of the 16th day of June 2008, by and
between DUKE ENERGY CORPORATION, a Delaware corporation, having its principal office at 526 South
Church Street, Charlotte, North Carolina 28202 (the “Corporation”), and The Bank of New York Trust
Company, N.A., a national banking association, as Trustee (herein called the “Trustee”).

WITNESSETH:

     WHEREAS, the Corporation has heretofore entered into an Indenture, dated as of June 3, 2008
(the “Original Indenture”), with The Bank of New York Trust Company, N.A., as Trustee;

     WHEREAS, the Original Indenture is incorporated herein by this reference and the Original
Indenture, as may be amended and supplemented to the date hereof, including by this First
Supplemental Indenture, is herein called the “Indenture”;

     WHEREAS, under the Indenture, a new series of Securities may at any time be established in
accordance with the provisions of the Indenture and the terms of such series may be described by a
supplemental indenture executed by the Corporation and the Trustee;

     WHEREAS, the Corporation hereby proposes to create under the Indenture two additional series
of Securities;

     WHEREAS, additional Securities of other series hereafter established, except as may be limited
in the Indenture as at the time supplemented and modified, may be issued from time to time pursuant
to the Indenture as at the time supplemented and modified; and

     WHEREAS, all conditions necessary to authorize the execution and delivery of this First
Supplemental Indenture and to make it a valid and binding obligation of the Corporation have been
done or performed.

     NOW, THEREFORE, in consideration of the agreements and obligations set forth herein and for
other good and valuable consideration, the sufficiency of which is hereby acknowledged, the parties
hereto hereby agree as follows:

ARTICLE 1

5.65% SENIOR NOTES DUE 2013

     Section 1.01. Establishment. There is hereby established a new series of Securities
to be issued under the Indenture, to be designated as the Corporation’s 5.65% Senior Notes due 2013
(the “2013 Notes”).

     There are to be authenticated and delivered $250,000,000 principal amount of the 2013 Notes,
and no further 2013 Notes shall be authenticated and delivered except as provided by Section 304,
305, 306, 906 or 1106 of the Original Indenture and the last paragraph of Section 301 thereof. The
2013 Notes shall be issued in fully registered form without coupons.

 

 

     The 2013 Notes shall be in substantially the form set out in Exhibit A hereto, and the form of
the Trustee’s Certificate of Authentication for the 2013 Notes shall be in substantially the form
set forth in Exhibit B hereto.

     Each 2013 Note shall be dated the date of authentication thereof and shall bear interest from
the date of original issuance thereof or from the most recent Interest Payment Date to which
interest has been paid or duly provided for.

     Section 1.02. Definitions. The following defined terms used in this Article 1 shall,
unless the context otherwise requires, have the meanings specified below for purposes of the 2013
Notes. Capitalized terms used herein for which no definition is provided herein shall have the
meanings set forth in the Original Indenture.

     “Business Day” means a day other than (i) a Saturday or a Sunday, (ii) a day on which banking
institutions in New York, New York are authorized or obligated by law or executive order to remain
closed or (iii) a day on which the Corporate Trust Office is closed for business.

     “Interest Payment Date” means each June 15 and December 15 of each year, commencing December
15, 2008.

     “Original Issue Date” means June 16, 2008.

     “Regular Record Date” means, with respect to each Interest Payment Date, the close of business
on the 15th calendar day prior to such Interest Payment Date (whether or not a Business Day).

     “Stated Maturity” means June 15, 2013.

     Section 1.03. Payment of Principal and Interest. The principal of the 2013 Notes
shall be due at Stated Maturity (unless earlier redeemed). The unpaid principal amount of the 2013
Notes shall bear interest at the rate of 5.65% per annum until paid or duly provided for, such
interest to accrue from June 16, 2008 or from the most recent Interest Payment Date to which
interest has been paid or duly provided for. Interest shall be paid semi-annually in arrears on
each Interest Payment Date to the Person or Persons in whose name the 2013 Notes are registered on
the Regular Record Date for such Interest Payment Date; provided that interest payable at the
Stated Maturity or on a Redemption Date as provided herein shall be paid to the Person to whom
principal is payable. Any such interest that is not so punctually paid or duly provided for shall
forthwith cease to be payable to the Holders on such Regular Record Date and may either be paid to
the Person or Persons in whose name the 2013 Notes are registered at the close of business on a
Special Record Date for the payment of such defaulted interest to be fixed by the Trustee (“Special
Record Date”), notice whereof shall be given to Holders of the 2013 Notes not less than ten (10)
days prior to such Special Record Date, or be paid at any time in any other lawful manner not
inconsistent with the requirements of any securities exchange, if any, on which the 2013 Notes may
be listed, and upon such notice as may be required by any such exchange, all as more fully provided
in the Original Indenture.

     Payments of interest on the 2013 Notes shall include interest accrued to but excluding the
respective Interest Payment Dates. Interest payments for the 2013 Notes shall be computed and

-2-

 

paid on the basis of a 360-day year of twelve 30-day months. In the event that any date on
which interest is payable on the 2013 Notes is not a Business Day, then payment of the interest
payable on such date shall be made on the next succeeding day that is a Business Day (and without
any interest or payment in respect of any such delay) with the same force and effect as if made on
the date the payment was originally payable.

     Payment of principal of, premium, if any, and interest on the 2013 Notes shall be made in such
coin or currency of the United States of America as at the time of payment is legal tender for
payment of public and private debts. Payments of principal of, premium, if any, and interest on
2013 Notes represented by a Global Security shall be made by wire transfer of immediately available
funds to the Holder of such Global Security, provided that, in the case of payments of principal
and premium, if any, such Global Security is first surrendered to the Paying Agent. If any of the
2013 Notes are no longer represented by a Global Security, (i) payments of principal, premium, if
any, and interest due at the Stated Maturity or earlier redemption of such 2013 Notes shall be made
at the office of the Paying Agent upon surrender of such 2013 Notes to the Paying Agent and (ii)
payments of interest shall be made, at the option of the Corporation, subject to such surrender
where applicable, (A) by check mailed to the address of the Person entitled thereto as such address
shall appear in the Security Register or (B) by wire transfer at such place and to such account at
a banking institution in the United States as may be designated in writing to the Trustee at least
sixteen (16) days prior to the date for payment by the Person entitled thereto.

     Section 1.04. Denominations. The 2013 Notes shall be issued in denominations of
$2,000 or any integral multiple of $1,000 in excess thereof.

     Section 1.05. Global Securities. The 2013 Notes shall initially be issued in the form
of one or more Global Securities registered in the name of the Depositary (which initially shall be
The Depository Trust Company) or its nominee. Except under the limited circumstances described
below, 2013 Notes represented by such Global Security or Global Securities shall not be
exchangeable for, and shall not otherwise be issuable as, 2013 Notes in definitive form. The Global
Securities described in this Article 1 may not be transferred except by the Depositary to a nominee
of the Depositary or by a nominee of the Depositary to the Depositary or another nominee of the
Depositary or to a successor Depositary or its nominee.

     A Global Security shall be exchangeable for 2013 Notes registered in the names of persons
other than the Depositary or its nominee only if (i) the Depositary notifies the Corporation that
it is unwilling or unable to continue as a Depositary for such Global Security and no successor
Depositary shall have been appointed by the Corporation within 90 days of receipt by the
Corporation of such notification, or if at any time the Depositary ceases to be a clearing agency
registered under the Exchange Act at a time when the Depositary is required to be so registered to
act as such Depositary and no successor Depositary shall have been appointed by the Corporation
within 90 days after it becomes aware of such cessation, (ii) an Event of Default has occurred and
is continuing with respect to the 2013 Notes, or (iii) the Corporation in its sole discretion, and
subject to the procedures of the Depository, determines that such Global Security shall be so
exchangeable. Any Global Security that is exchangeable pursuant to the preceding sentence shall be
exchangeable for 2013 Notes registered in such names as the Depositary shall direct.

-3-

 

     Section 1.06. Redemption. The 2013 Notes shall be redeemable, in whole or from time
to time in part ($2,000 or any integral multiple of $1,000 in excess thereof), at the option of the
Corporation on any date (a “Redemption Date”), at a Redemption Price equal to the greater of (i)
100% of the principal amount of the 2013 Notes to be redeemed and (ii) the sum of the present
values of the remaining scheduled payments of principal and interest thereon (exclusive of interest
accrued to such Redemption Date) discounted to such Redemption Date on a semi-annual basis
(assuming a 360-day year consisting of twelve 30-day months) at the Treasury Rate plus 40 basis
points, plus, in either case, accrued and unpaid interest on the principal amount being redeemed to
such Redemption Date.

     “Treasury Rate” means, with respect to any Redemption Date for the 2013 Notes, (i) the yield,
under the heading which represents the average for the immediately preceding week, appearing in the
most recently published statistical release designated “H.15(519)” or any successor publication
which is published weekly by the Board of Governors of the Federal Reserve System and which
establishes yields on actively traded United States Treasury securities adjusted to constant
maturity under the caption “Treasury Constant Maturities,” for the maturity corresponding to the
Comparable Treasury Issue (if no maturity is within three months before or after the Stated
Maturity, yields for the two published maturities most closely corresponding to the Comparable
Treasury Issue shall be determined, and the Treasury Rate shall be interpolated or extrapolated
from such yields on a straight-line basis, rounding to the nearest month) or (ii) if such release
(or any successor release) is not published during the week preceding the calculation date or does
not contain such yields, the rate per annum equal to the semi-annual equivalent yield to maturity
of the Comparable Treasury Issue, calculated using a price for the Comparable Treasury Issue
(expressed as a percentage of its principal amount) equal to the Comparable Treasury Price for such
Redemption Date. The Treasury Rate shall be calculated on the third Business Day preceding the
Redemption Date.

     “Comparable Treasury Issue” when used in this Section 1.06 means the United States Treasury
security selected by the Quotation Agent as having a maturity comparable to the remaining term of
the 2013 Notes to be redeemed that would be utilized, at the time of selection and in accordance
with customary financial practice, in pricing new issues of corporate debt securities of comparable
maturity to the remaining term of such 2013 Notes.

     “Quotation Agent” means a Reference Treasury Dealer appointed by the Corporation.

     “Comparable Treasury Price” means, with respect to any Redemption Date for the 2013 Notes, (1)
the average of three Reference Treasury Dealer Quotations for such Redemption Date, after excluding
the highest and lowest such Reference Treasury Dealer Quotations, or (2) if fewer than three such
Reference Treasury Dealer Quotations are obtained, the average of all such Reference Treasury
Dealer Quotations.

     “Reference Treasury Dealer” means each of Credit Suisse Securities (USA) LLC, Goldman, Sachs &
Co., and Lehman Brothers Inc., and their respective successors; provided, however, that if any of
the foregoing ceases to be a primary U.S. Government securities dealer in the United States (a
“Primary Treasury Dealer”), the Corporation will substitute therefor another Primary Treasury
Dealer.

-4-

 

     “Reference Treasury Dealer Quotations” means, with respect to each Reference Treasury Dealer
and any Redemption Date, the average, as determined by the Quotation Agent, of the bid and asked
prices for the Comparable Treasury Issue (expressed in each case as a percentage of its principal
amount) quoted in writing to the Quotation Agent by such Reference Treasury Dealer at 5:00 p.m.,
New York City time, on the third Business Day preceding such Redemption Date.

     The Corporation shall notify the Trustee of the Redemption Price with respect to the foregoing
redemption promptly after the calculation thereof. The Trustee shall not be responsible for
calculating said Redemption Price.

     If less than all of the 2013 Notes are to be redeemed, the Trustee shall select the 2013 Notes
or portions of 2013 Notes to be redeemed by such method as the Trustee shall deem fair and
appropriate. The Trustee may select for redemption 2013 Notes and portions of 2013 Notes in amounts
of $2,000 or any integral multiple of $1,000 in excess thereof.

     The 2013 Notes shall not have a sinking fund.

     Section 1.07. Paying Agent. The Trustee shall initially serve as Paying Agent with
respect to the 2013 Notes, with the Place of Payment initially being the Corporate Trust Office.

ARTICLE 2

6.25% SENIOR NOTES DUE 2018

     Section 2.01. Establishment. There is hereby established a new series of Securities
to be issued under the Indenture, to be designated as the Corporation’s 6.25% Senior Notes due 2018
(the “2018 Notes”).

     There are to be authenticated and delivered $250,000,000 principal amount of the 2018 Notes,
and no further 2018 Notes shall be authenticated and delivered except as provided by Section 304,
305, 306, 906 or 1106 of the Original Indenture and the last paragraph of Section 301 thereof. The
2018 Notes shall be issued in fully registered form without coupons.

     The 2018 Notes shall be in substantially the form set out in Exhibit C hereto, and the form of
the Trustee’s Certificate of Authentication for the 2018 Notes shall be in substantially the form
set forth in Exhibit D hereto.

     Each 2018 Note shall be dated the date of authentication thereof and shall bear interest from
the date of original issuance thereof or from the most recent Interest Payment Date to which
interest has been paid or duly provided for.

-5-

 

     Section 2.02. Definitions. The following defined terms used in this Article 2 shall,
unless the context otherwise requires, have the meanings specified below for purposes of the 2018
Notes. Capitalized terms used herein for which no definition is provided herein shall have the
meanings set forth in the Original Indenture.

     “Business Day” means a day other than (i) a Saturday or a Sunday, (ii) a day on which banking
institutions in New York, New York are authorized or obligated by law or executive order to remain
closed or (iii) a day on which the Corporate Trust Office is closed for business.

     “Interest Payment Date” means each June 15 and December 15 of each year, commencing December
15, 2008.

     “Original Issue Date” means June 16, 2008.

     “Regular Record Date” means, with respect to each Interest Payment Date, the close of business
on the 15th calendar day prior to such Interest Payment Date (whether or not a Business Day).

     “Stated Maturity” means June 15, 2018.

     Section 2.03. Payment of Principal and Interest. The principal of the 2018 Notes
shall be due at Stated Maturity (unless earlier redeemed). The unpaid principal amount of the 2018
Notes shall bear interest at the rate of 6.25% per annum until paid or duly provided for, such
interest to accrue from June 16, 2008 or from the most recent Interest Payment Date to which
interest has been paid or duly provided for. Interest shall be paid semi-annually in arrears on
each Interest Payment Date to the Person or Persons in whose name the 2018 Notes are registered on
the Regular Record Date for such Interest Payment Date; provided that interest payable at the
Stated Maturity or on a Redemption Date as provided herein shall be paid to the Person to whom
principal is payable. Any such interest that is not so punctually paid or duly provided for shall
forthwith cease to be payable to the Holders on such Regular Record Date and may either be paid to
the Person or Persons in whose name the 2018 Notes are registered at the close of business on a
Special Record Date for the payment of such defaulted interest to be fixed by the Trustee (“Special
Record Date”), notice whereof shall be given to Holders of the 2018 Notes not less than ten (10)
days prior to such Special Record Date, or be paid at any time in any other lawful manner not
inconsistent with the requirements of any securities exchange, if any, on which the 2018 Notes may
be listed, and upon such notice as may be required by any such exchange, all as more fully provided
in the Original Indenture.

     Payments of interest on the 2018 Notes shall include interest accrued to but excluding the
respective Interest Payment Dates. Interest payments for the 2018 Notes shall be computed and paid
on the basis of a 360-day year of twelve 30-day months. In the event that any date on which
interest is payable on the 2018 Notes is not a Business Day, then payment of the interest payable
on such date shall be made on the next succeeding day that is a Business Day (and without any
interest or payment in respect of any such delay) with the same force and effect as if made on the
date the payment was originally payable.

     Payment of principal of, premium, if any, and interest on the 2018 Notes shall be made in such
coin or currency of the United States of America as at the time of payment is legal tender

-6-

 

for payment of public and private debts. Payments of principal of, premium, if any, and
interest on 2018 Notes represented by a Global Security shall be made by wire transfer of
immediately available funds to the Holder of such Global Security, provided that, in the case of
payments of principal and premium, if any, such Global Security is first surrendered to the Paying
Agent. If any of the 2018 Notes are no longer represented by a Global Security, (i) payments of
principal, premium, if any, and interest due at the Stated Maturity or earlier redemption of such
2018 Notes shall be made at the office of the Paying Agent upon surrender of such 2018 Notes to the
Paying Agent and (ii) payments of interest shall be made, at the option of the Corporation, subject
to such surrender where applicable, (A) by check mailed to the address of the Person entitled
thereto as such address shall appear in the Security Register or (B) by wire transfer at such place
and to such account at a banking institution in the United States as may be designated in writing
to the Trustee at least sixteen (16) days prior to the date for payment by the Person entitled
thereto.

     Section 2.04. Denominations. The 2018 Notes shall be issued in denominations of
$2,000 or any integral multiple of $1,000 in excess thereof.

     Section 2.05. Global Securities. The 2018 Notes shall initially be issued in the form
of one or more Global Securities registered in the name of the Depositary (which initially shall be
The Depository Trust Company) or its nominee. Except under the limited circumstances described
below, 2018 Notes represented by such Global Security or Global Securities shall not be
exchangeable for, and shall not otherwise be issuable as, 2018 Notes in definitive form. The Global
Securities described in this Article 2 may not be transferred except by the Depositary to a nominee
of the Depositary or by a nominee of the Depositary to the Depositary or another nominee of the
Depositary or to a successor Depositary or its nominee.

     A Global Security shall be exchangeable for 2018 Notes registered in the names of persons
other than the Depositary or its nominee only if (i) the Depositary notifies the Corporation that
it is unwilling or unable to continue as a Depositary for such Global Security and no successor
Depositary shall have been appointed by the Corporation within 90 days of receipt by the
Corporation of such notification, or if at any time the Depositary ceases to be a clearing agency
registered under the Exchange Act at a time when the Depositary is required to be so registered to
act as such Depositary and no successor Depositary shall have been appointed by the Corporation
within 90 days after it becomes aware of such cessation, (ii) an Event of Default has occurred and
is continuing with respect to the 2018 Notes, or (iii) the Corporation in its sole discretion, and
subject to the procedures of the Depository, determines that such Global Security shall be so
exchangeable. Any Global Security that is exchangeable pursuant to the preceding sentence shall be
exchangeable for 2018 Notes registered in such names as the Depositary shall direct.

     Section 2.06. Redemption. The 2018 Notes shall be redeemable, in whole or from time
to time in part ($2,000 or any integral multiple of $1,000 in excess thereof), at the option of the
Corporation on any date (a “Redemption Date”), at a Redemption Price equal to the greater of (i)
100% of the principal amount of the 2018 Notes to be redeemed and (ii) the sum of the present
values of the remaining scheduled payments of principal and interest thereon (exclusive of interest
accrued to such Redemption Date) discounted to such Redemption Date on a semi-annual basis
(assuming a 360-day year consisting of twelve 30-day months) at the Treasury Rate

-7-

 

plus 40 basis points, plus, in either case, accrued and unpaid interest on the principal
amount being redeemed to such Redemption Date.

     “Treasury Rate” means, with respect to any Redemption Date for the 2018 Notes, (i) the yield,
under the heading which represents the average for the immediately preceding week, appearing in the
most recently published statistical release designated “H.15(519)” or any successor publication
which is published weekly by the Board of Governors of the Federal Reserve System and which
establishes yields on actively traded United States Treasury securities adjusted to constant
maturity under the caption “Treasury Constant Maturities,” for the maturity corresponding to the
Comparable Treasury Issue (if no maturity is within three months before or after the Stated
Maturity, yields for the two published maturities most closely corresponding to the Comparable
Treasury Issue shall be determined, and the Treasury Rate shall be interpolated or extrapolated
from such yields on a straight-line basis, rounding to the nearest month) or (ii) if such release
(or any successor release) is not published during the week preceding the calculation date or does
not contain such yields, the rate per annum equal to the semi-annual equivalent yield to maturity
of the Comparable Treasury Issue, calculated using a price for the Comparable Treasury Issue
(expressed as a percentage of its principal amount) equal to the Comparable Treasury Price for such
Redemption Date. The Treasury Rate shall be calculated on the third Business Day preceding the
Redemption Date.

     “Comparable Treasury Issue” when used in this Section 2.06 means the United States Treasury
security selected by the Quotation Agent as having a maturity comparable to the remaining term of
the 2018 Notes to be redeemed that would be utilized, at the time of selection and in accordance
with customary financial practice, in pricing new issues of corporate debt securities of comparable
maturity to the remaining term of such 2018 Notes.

     “Quotation Agent” means a Reference Treasury Dealer appointed by the Corporation.

     “Comparable Treasury Price” means, with respect to any Redemption Date for the 2018 Notes, (1)
the average of three Reference Treasury Dealer Quotations for such Redemption Date, after excluding
the highest and lowest such Reference Treasury Dealer Quotations, or (2) if fewer than three such
Reference Treasury Dealer Quotations are obtained, the average of all such Reference Treasury
Dealer Quotations.

     “Reference Treasury Dealer” means each of Credit Suisse Securities (USA) LLC, Goldman, Sachs &
Co., and Lehman Brothers Inc., and their respective successors; provided, however, that if any of
the foregoing ceases to be a primary U.S. Government securities dealer in the United States (a
“Primary Treasury Dealer”), the Corporation will substitute therefor another Primary Treasury
Dealer.

     “Reference Treasury Dealer Quotations” means, with respect to each Reference Treasury Dealer
and any Redemption Date, the average, as determined by the Quotation Agent, of the bid and asked
prices for the Comparable Treasury Issue (expressed in each case as a percentage of its principal
amount) quoted in writing to the Quotation Agent by such Reference Treasury Dealer at 5:00 p.m.,
New York City time, on the third Business Day preceding such Redemption Date.

-8-

 

     The Corporation shall notify the Trustee of the Redemption Price with respect to the foregoing
redemption promptly after the calculation thereof. The Trustee shall not be responsible for
calculating said Redemption Price.

     If less than all of the 2018 Notes are to be redeemed, the Trustee shall select the 2018 Notes
or portions of 2018 Notes to be redeemed by such method as the Trustee shall deem fair and
appropriate. The Trustee may select for redemption 2018 Notes and portions of 2018 Notes in amounts
of $2,000 or any integral multiple of $1,000 in excess thereof.

     The 2018 Notes shall not have a sinking fund.

     Section 2.07. Paying Agent. The Trustee shall initially serve as Paying Agent with
respect to the 2018 Notes, with the Place of Payment initially being the Corporate Trust Office.

ARTICLE 3

MISCELLANEOUS PROVISIONS

     Section 3.01. Recitals by the Corporation. The recitals in this First Supplemental
Indenture are made by the Corporation only and not by the Trustee, and all of the provisions
contained in the Original Indenture in respect of the rights, privileges, immunities, powers and
duties of the Trustee shall be applicable in respect of the 2013 Notes and the 2018 Notes and of
this First Supplemental Indenture as fully and with like effect as if set forth herein in full.

     Section 3.02. Ratification and Incorporation of Original Indenture. As supplemented
hereby, the Original Indenture is in all respects ratified and confirmed, and the Original
Indenture and this First Supplemental Indenture shall be read, taken and construed as one and the
same instrument.

     Section 3.03. Executed in Counterparts. This First Supplemental Indenture may be
executed in several counterparts, each of which shall be deemed to be an original, and such
counterparts shall together constitute but one and the same instrument.

-9-

 

     IN WITNESS WHEREOF, each party hereto has caused this instrument to be signed in its name and
behalf by its duly authorized officer, all as of the day and year first above written.

	 	 	 	 	 
	 

	 	Duke Energy Corporation	 	 
	 
	 	 	 	 
	 

	 	By: /s/ M. Allen Carrick
 
	 	 
	 

	 	Name: M. Allen Carrick	 	 
	 

	 	Title: Assistant Treasurer	 	 
	 
	 	 	 	 
	 

	 	The Bank of New York Trust Company, N.A.,
as Trustee	 	 
	 
	 	 	 	 
	 

	 	By: /s/ Van K. Brown	 	 
	 
	 	
 
	 	 
	 

	 	Name: Van K. Brown	 	 
	 

	 	Title: Vice President	 	 

-10-

 

EXHIBIT A

FORM OF

5.65% SENIOR NOTE DUE 2013

			
	 	 	 
	No.
	 	CUSIP No. 26441C AA3

DUKE ENERGY CORPORATION

5.65% SENIOR NOTE DUE 2013

Principal Amount: $

Regular Record Date: Close of business on the 15th calendar day prior to the relevant
Interest Payment Date (whether or not a Business Day)

Original Issue Date: June 16, 2008

Stated Maturity: June 15, 2013

Interest Payment Dates: Semi-annually on June 15 and December 15 of each year, commencing December
15, 2008.

Interest Rate: 5.65% per annum

Authorized Denomination: $2,000 or any integral multiple of $1,000 in excess thereof

     Duke Energy Corporation, a Delaware corporation (the “Corporation”, which term includes any
successor corporation under the Indenture referred to on the reverse hereof), for value received,
hereby promises to pay to      , or registered assigns, the principal sum of

     DOLLARS ($      ) on the Stated Maturity shown above and to pay interest thereon from the Original
Issue Date shown above, or from the most recent Interest Payment Date to which interest has been
paid or duly provided for, semi-annually in arrears on each Interest Payment Date as specified
above, commencing on December 15, 2008 and on the Stated Maturity at the rate per annum shown above
(the “Interest Rate”) until the principal hereof is paid or made available for payment and on any
overdue principal and on any overdue installment of interest. The interest so payable, and
punctually paid or duly provided for, on any Interest Payment Date (other than an Interest Payment
Date that is the Stated Maturity or a Redemption Date) will, as provided in the Indenture, be paid
to the Person in whose name this 5.65% Senior Note due 2013 (this “Security”) is registered on the
Regular Record Date as specified above next preceding such Interest Payment Date; provided that any
interest payable at Stated Maturity or on a Redemption Date will be paid to the Person to whom
principal is payable. Except as otherwise provided in the Indenture, any such interest not so
punctually paid or duly provided for will forthwith cease to be payable to the Holder on such
Regular Record Date and may either be paid to the Person in whose name this Security is registered
at the close of business on a Special Record Date for the payment of such Defaulted Interest to be
fixed by the Trustee, notice whereof shall be given to Holders of Securities of this series not
less than 10 days prior to such Special Record Date, or be paid at any time in any other lawful
manner not inconsistent with the requirements of any securities exchange, if any, on which the
Securities shall be listed, and upon

A-1

 

such notice as may be required by any such exchange, all as more fully provided in the
Indenture.

     Payments of interest on this Security will include interest accrued to but excluding the
respective Interest Payment Dates. Interest payments for this Security shall be computed and paid
on the basis of a 360-day year of twelve 30-day months and will accrue from June 16, 2008 or from
the most recent Interest Payment Date to which interest has been paid or duly provided for. In the
event that any date on which interest is payable on this Security is not a Business Day, then
payment of the interest payable on such date will be made on the next succeeding day that is a
Business Day (and without any interest or payment in respect of any such delay) with the same force
and effect as if made on the date the payment was originally payable. “Business Day” means a day
other than (i) a Saturday or a Sunday, (ii) a day on which banking institutions in New York, New
York are authorized or obligated by law or executive order to remain closed or (iii) a day on which
the Corporate Trust Office is closed for business.

     Payment of principal of, premium, if any, and interest on the Securities of this series shall
be made in such coin or currency of the United States of America as at the time of payment is legal
tender for payment of public and private debts. Payments of principal of, premium, if any, and
interest on the Securities of this series represented by a Global Security shall be made by wire
transfer of immediately available funds to the Holder of such Global Security, provided that, in
the case of payments of principal and premium, if any, such Global Security is first surrendered to
the Paying Agent. If any of the Securities of this series are no longer represented by a Global
Security, (i) payments of principal, premium, if any, and interest due at the Stated Maturity or
earlier redemption of such Securities shall be made at the office of the Paying Agent upon
surrender of such Securities to the Paying Agent, and (ii) payments of interest shall be made, at
the option of the Corporation, subject to such surrender where applicable, (A) by check mailed to
the address of the Person entitled thereto as such address shall appear in the Security Register or
(B) by wire transfer at such place and to such account at a banking institution in the United
States as may be designated in writing to the Trustee at least sixteen (16) days prior to the date
for payment by the Person entitled thereto.

     The Securities of this series shall be redeemable, in whole or from time to time in part, at
the option of the Corporation on any date (a “Redemption Date”), at a Redemption Price equal to the
greater of (i) 100% of the principal amount of the Securities of this series to be redeemed and
(ii) the sum of the present values of the remaining scheduled payments of principal and interest
thereon (exclusive of interest accrued to such Redemption Date) discounted to such Redemption Date
on a semi-annual basis (assuming a 360-day year consisting of twelve 30-day months) at the Treasury
Rate plus 40 basis points, plus, in either case, accrued and unpaid interest on the principal
amount being redeemed to such Redemption Date.

     “Treasury Rate” means, with respect to any Redemption Date for the Securities of this series,
(i) the yield, under the heading which represents the average for the immediately preceding week,
appearing in the most recently published statistical release designated “H.15(519)” or any
successor publication which is published weekly by the Board of Governors of the Federal Reserve
System and which establishes yields on actively traded United States Treasury securities adjusted
to constant maturity under the caption “Treasury Constant Maturities,” for the maturity
corresponding to the Comparable Treasury Issue (if no maturity is

A-2

 

within three months before or after the Stated Maturity, yields for the two published
maturities most closely corresponding to the Comparable Treasury Issue shall be determined, and the
Treasury Rate shall be interpolated or extrapolated from such yields on a straight-line basis,
rounding to the nearest month) or (ii) if such release (or any successor release) is not published
during the week preceding the calculation date or does not contain such yields, the rate per annum
equal to the semi-annual equivalent yield to maturity of the Comparable Treasury Issue, calculated
using a price for the Comparable Treasury Issue (expressed as a percentage of its principal amount)
equal to the Comparable Treasury Price for such Redemption Date. The Treasury Rate shall be
calculated on the third Business Day preceding the Redemption Date.

     “Comparable Treasury Issue” means the United States Treasury security selected by the
Quotation Agent as having a maturity comparable to the remaining term of the Securities of this
series to be redeemed that would be utilized, at the time of selection and in accordance with
customary financial practice, in pricing new issues of corporate debt securities of comparable
maturity to the remaining term of such Securities of this series.

     “Quotation Agent” means a Reference Treasury Dealer appointed by the Corporation.

     “Comparable Treasury Price” means, with respect to any Redemption Date for the Securities of
this series, (1) the average of three Reference Treasury Dealer Quotations for such Redemption
Date, after excluding the highest and lowest such Reference Treasury Dealer Quotations, or (2) if
fewer than three such Reference Treasury Dealer Quotations are obtained, the average of all such
Reference Treasury Dealer Quotations.

     “Reference Treasury Dealer” means each of Credit Suisse Securities (USA) LLC, Goldman, Sachs &
Co., and Lehman Brothers Inc., and their respective successors; provided, however, that if any of
the foregoing ceases to be a primary U.S. Government securities dealer in the United States (a
“Primary Treasury Dealer”), the Corporation will substitute therefor another Primary Treasury
Dealer.

     “Reference Treasury Dealer Quotations” means, with respect to each Reference Treasury Dealer
and any Redemption Date, the average, as determined by the Quotation Agent, of the bid and asked
prices for the Comparable Treasury Issue (expressed in each case as a percentage of its principal
amount) quoted in writing to the Quotation Agent by such Reference Treasury Dealer at 5:00 p.m.,
New York City time, on the third Business Day preceding such Redemption Date.

     The Corporation shall notify the Trustee of the Redemption Price with respect to the foregoing
redemption promptly after the calculation thereof. The Trustee shall not be responsible for
calculating said Redemption Price.

     Notice of any redemption by the Corporation will be mailed at least 30 days but not more than
60 days before any Redemption Date to each Holder of Securities of this series to be redeemed. If
Notice of a redemption is provided and funds are deposited as required, interest will cease to
accrue on and after the Redemption Date on the Securities of this series or portions of Securities
of this series called for redemption. In the event that any Redemption Date is not a Business Day,
the Corporation will pay the Redemption Price on the next Business Day without any interest or
other payment in respect of any such delay. If less than all the Securities of this

A-3

 

series are to be redeemed at the option of the Corporation, the Trustee shall select, in such
manner as it shall deem fair and appropriate, the Securities of this series to be redeemed in whole
or in part. The Trustee may select for redemption Securities of this series and portions of the
Securities of this series in amounts of $2,000 or any integral multiple of $1,000 in excess
thereof.

     In the event of redemption of this Security in part only, a new Security or Securities of this
series and of like tenor for the unredeemed portion hereof will be issued in the name of the Holder
hereof upon the surrender hereof.

     The Securities of this series shall not have a sinking fund.

     The Securities of this series shall constitute the direct unsecured and unsubordinated debt
obligations of the Corporation and shall rank equally in priority with the Corporation’s existing
and future unsecured and unsubordinated indebtedness.

     REFERENCE IS HEREBY MADE TO THE FURTHER PROVISIONS OF THIS SECURITY SET FORTH ON THE REVERSE
HEREOF, WHICH FURTHER PROVISIONS SHALL FOR ALL PURPOSES HAVE THE SAME EFFECT AS IF SET FORTH AT
THIS PLACE.

     Unless the certificate of authentication hereon has been executed by the Trustee by manual
signature, this Security shall not be entitled to any benefit under the Indenture or be valid or
obligatory for any purpose.

A-4

 

     IN WITNESS WHEREOF, the Corporation has caused this instrument to be duly executed.

	 	 	 	 	 	 	 
	 	 	Duke Energy Corporation	 	 
	 
	 	 	 	 	 	 
	 

	 	By:	 	 	 	 
	 

	 	Name:	 	 

M. Allen Carrick
	 	 
	 

	 	Title:
	 	Assistant Treasurer	 	 

CERTIFICATE OF AUTHENTICATION

     This is one of the Securities of the series designated therein referred to in the
within-mentioned Indenture.

	 	 	 	 	 	 	 
	 	 	The Bank of New York Trust Company, N.A.,

     as Trustee	 	 
	 
	 	 	 	 	 	 
	 

	 	By:	 	 	 	 
	 

	 	 	 	 

          Authorized Signatory
	 	 

A-5

 

(Reverse Side of Security)

     This 5.65% Senior Note due 2013 is one of a duly authorized issue of Securities of the
Corporation (the “Securities”), issued and issuable in one or more series under an Indenture, dated
as of June 3, 2008, as supplemented (the “Indenture”), between the Corporation and The Bank of New
York Trust Company, N.A., as Trustee (the “Trustee,” which term includes any successor trustee
under the Indenture), to which Indenture and all indentures supplemental thereto reference is
hereby made for a statement of the respective rights, limitation of rights, duties and immunities
thereunder of the Corporation, the Trustee and the Holders of the Securities issued thereunder and
of the terms upon which said Securities are, and are to be, authenticated and delivered. This
Security is one of the series designated on the face hereof as 5.65% Senior Notes due 2013
initially in the aggregate principal amount of $250,000,000. Capitalized terms used herein for
which no definition is provided herein shall have the meanings set forth in the Indenture.

     If an Event of Default with respect to the Securities of this series shall occur and be
continuing, the principal of the Securities of this series may be declared due and payable in the
manner, with the effect and subject to the conditions provided in the Indenture.

     The Indenture permits, with certain exceptions as therein provided, the amendment thereof and
the modification of the rights and obligations of the Corporation and the rights of the Holders of
the Securities of all series affected under the Indenture at any time by the Corporation and the
Trustee with the consent of the Holders of not less than a majority in principal amount of the
Outstanding Securities of all series affected thereby (voting as one class). The Indenture contains
provisions permitting the Holders of not less than a majority in principal amount of the
Outstanding Securities of all series with respect to which a default under the Indenture shall have
occurred and be continuing (voting as one class), on behalf of the Holders of the Securities of all
such series, to waive, with certain exceptions, such default under the Indenture and its
consequences. The Indenture also permits the Holders of not less than a majority in principal
amount of the Securities of each series at the time Outstanding, on behalf of the Holders of all
Securities of such series, to waive compliance by the Corporation with certain provisions of the
Indenture affecting such series. Any such consent or waiver by the Holder of this Security shall be
conclusive and binding upon such Holder and upon all future Holders of this Security and of any
Security issued upon the registration of transfer hereof or in exchange hereof or in lieu hereof,
whether or not notation of such consent or waiver is made upon this Security.

     No reference herein to the Indenture and no provision of this Security or of the Indenture
shall alter or impair the obligation of the Corporation, which is absolute and unconditional, to
pay the principal of and interest on this Security at the times, place and rate, and in the coin or
currency, herein prescribed.

     As provided in the Indenture and subject to certain limitations therein set forth, the
transfer of this Security is registrable in the Security Register, upon surrender of this Security
for registration of transfer at the office or agency of the Corporation for such purpose, duly
endorsed by, or accompanied by a written instrument of transfer in form satisfactory to the
Corporation and the Security Registrar and duly executed by, the Holder hereof or his attorney duly
authorized in writing, and thereupon one or more new Securities of this series, of authorized

A-6

 

denominations and of like tenor and for the same aggregate principal amount, will be issued to
the designated transferee or transferees. No service charge shall be made for any such registration
of transfer or exchange, but the Corporation may require payment of a sum sufficient to cover any
tax or other governmental charge payable in connection therewith.

     The Indenture contains provisions for defeasance at any time of the entire indebtedness of the
Securities of this series and for covenant defeasance at any time of certain covenants in the
Indenture upon compliance with certain conditions set forth in the Indenture.

     Prior to due presentment of this Security for registration of transfer, the Corporation, the
Trustee and any agent of the Corporation or the Trustee may treat the Person in whose name this
Security is registered as the owner hereof for all purposes, whether or not this Security be
overdue, and neither the Corporation, the Trustee nor any such agent shall be affected by notice to
the contrary.

     The Securities of this series are issuable only in registered form without coupons in
denominations of $2,000 or any integral multiple of $1,000 in excess thereof. As provided in the
Indenture and subject to the limitations therein set forth, Securities of this series are
exchangeable for a like aggregate principal amount of Securities of this series of a different
authorized denomination, as requested by the Holder surrendering the same upon surrender of the
Security or Securities to be exchanged at the office or agency of the Corporation.

     This Security shall be governed by, and construed in accordance with, the laws of the State of
New York.

A-7

 

ABBREVIATIONS

     The following abbreviations, when used in the inscription on the face of this instrument,
shall be construed as though they were written out in full according to applicable laws or
regulations:

	 	 	 	 	 	 	 	 	 
	TEN COM—as tenants in common

	 	UNIF GIFT MIN ACT-
	 	 	 	Custodian	 	 
	 

	 	 	 	 
	 	 	 	 
	 

	 	 	 	(Cust)
	 	 	 	(Minor)
	 
	 	 	 	 	 	 	 	 
	TEN ENT—as tenants by the entireties
	 	 	 	 	 	 	 	 

	 	 	 	 	 
	JT TEN—as joint tenants with rights of
survivorship and not as tenants in common

	 	under Uniform Gifts to
Minors Act
                    	 	 
	 

	 	               (State)	 	 

Additional abbreviations may also be used though not on the above list.

FOR VALUE RECEIVED, the undersigned hereby sell(s) and transfer(s) unto (please insert Social
Security or other identifying number of assignee)

PLEASE PRINT OR TYPEWRITE NAME AND ADDRESS, INCLUDING POSTAL ZIP CODE OF ASSIGNEE

the within Security and all rights thereunder, hereby irrevocably constituting and appointing agent
to transfer said Security on the books of the Corporation, with full power of substitution in the
premises.

Dated:                     

	 	 	 	 	 
	 	 	NOTICE: The signature to this assignment must
correspond with the name as written upon the face of
the within instrument in every particular without
alteration or enlargement, or any change whatever.
	 
	 	 	 	 
	 

	 	Signature Guarantee:	 	 
	 

	 	 	 	 

A-8

 

SIGNATURE GUARANTEE

     Signatures must be guaranteed by an “eligible guarantor institution” meeting the requirements
of the Security Registrar, which requirements include membership or participation in the Security
Transfer Agent Medallion Program (“STAMP”) or such other “signature guarantee program” as may be
determined by the Security Registrar in addition to, or in substitution for, STAMP, all in
accordance with the Securities Exchange Act of 1934, as amended.

A-9

 

EXHIBIT B

CERTIFICATE OF AUTHENTICATION

     This is one of the Securities of the series designated therein referred to in the
within-mentioned Indenture.

	 	 	 	 	 	 	 
	 	 	The Bank of New York Trust Company, N.A.,

     as Trustee	 	 
	 
	 	 	 	 	 	 
	 

	 	By:	 	 	 	 
	 

	 	 	 	 

          Authorized Signatory
	 	 

B-1

 

EXHIBIT C

FORM OF

6.25% SENIOR NOTE DUE 2018

			
	No.
	 	CUSIP No. 26441C AB1

DUKE ENERGY CORPORATION

6.25% SENIOR NOTE DUE 2018

Principal Amount: $

Regular Record Date: Close of business on the 15th calendar day prior to the relevant
Interest Payment Date (whether or not a Business Day)

Original Issue Date: June 16, 2008

Stated Maturity: June 15, 2018

Interest Payment Dates: Semi-annually on June 15 and December 15 of each year, commencing December
15, 2008.

Interest Rate: 6.25% per annum

Authorized Denomination: $2,000 or any integral multiple of $1,000 in excess thereof

     Duke Energy Corporation, a Delaware corporation (the “Corporation”, which term includes any
successor corporation under the Indenture referred to on the reverse hereof), for value received,
hereby promises to pay to           ,  or registered assigns, the principal sum of
          DOLLARS ($           ) on the Stated Maturity shown above and to pay interest thereon from the Original
Issue Date shown above, or from the most recent Interest Payment Date to which interest has been
paid or duly provided for, semi-annually in arrears on each Interest Payment Date as specified
above, commencing on December 15, 2008 and on the Stated Maturity at the rate per annum shown above
(the “Interest Rate”) until the principal hereof is paid or made available for payment and on any
overdue principal and on any overdue installment of interest. The interest so payable, and
punctually paid or duly provided for, on any Interest Payment Date (other than an Interest Payment
Date that is the Stated Maturity or a Redemption Date) will, as provided in the Indenture, be paid
to the Person in whose name this 6.25% Senior Note due 2018 (this “Security”) is registered on the
Regular Record Date as specified above next preceding such Interest Payment Date; provided that any
interest payable at Stated Maturity or on a Redemption Date will be paid to the Person to whom
principal is payable. Except as otherwise provided in the Indenture, any such interest not so
punctually paid or duly provided for will forthwith cease to be payable to the Holder on such
Regular Record Date and may either be paid to the Person in whose name this Security is registered
at the close of business on a Special Record Date for the payment of such Defaulted Interest to be
fixed by the Trustee, notice whereof shall be given to Holders of Securities of this series not
less than 10 days prior to such Special Record Date, or be paid at any time in any other lawful
manner not inconsistent with the requirements of any securities exchange, if any, on which the
Securities shall be listed, and upon

C-1

 

such notice as may be required by any such exchange, all as more fully provided in the
Indenture.

     Payments of interest on this Security will include interest accrued to but excluding the
respective Interest Payment Dates. Interest payments for this Security shall be computed and paid
on the basis of a 360-day year of twelve 30-day months and will accrue from June 16, 2008 or from
the most recent Interest Payment Date to which interest has been paid or duly provided for. In the
event that any date on which interest is payable on this Security is not a Business Day, then
payment of the interest payable on such date will be made on the next succeeding day that is a
Business Day (and without any interest or payment in respect of any such delay) with the same force
and effect as if made on the date the payment was originally payable. “Business Day” means a day
other than (i) a Saturday or a Sunday, (ii) a day on which banking institutions in New York, New
York are authorized or obligated by law or executive order to remain closed or (iii) a day on which
the Corporate Trust Office is closed for business.

     Payment of principal of, premium, if any, and interest on the Securities of this series shall
be made in such coin or currency of the United States of America as at the time of payment is legal
tender for payment of public and private debts. Payments of principal of, premium, if any, and
interest on the Securities of this series represented by a Global Security shall be made by wire
transfer of immediately available funds to the Holder of such Global Security, provided that, in
the case of payments of principal and premium, if any, such Global Security is first surrendered to
the Paying Agent. If any of the Securities of this series are no longer represented by a Global
Security, (i) payments of principal, premium, if any, and interest due at the Stated Maturity or
earlier redemption of such Securities shall be made at the office of the Paying Agent upon
surrender of such Securities to the Paying Agent, and (ii) payments of interest shall be made, at
the option of the Corporation, subject to such surrender where applicable, (A) by check mailed to
the address of the Person entitled thereto as such address shall appear in the Security Register or
(B) by wire transfer at such place and to such account at a banking institution in the United
States as may be designated in writing to the Trustee at least sixteen (16) days prior to the date
for payment by the Person entitled thereto.

     The Securities of this series shall be redeemable, in whole or from time to time in part, at
the option of the Corporation on any date (a “Redemption Date”), at a Redemption Price equal to the
greater of (i) 100% of the principal amount of the Securities of this series to be redeemed and
(ii) the sum of the present values of the remaining scheduled payments of principal and interest
thereon (exclusive of interest accrued to such Redemption Date) discounted to such Redemption Date
on a semi-annual basis (assuming a 360-day year consisting of twelve 30-day months) at the Treasury
Rate plus 40 basis points, plus, in either case, accrued and unpaid interest on the principal
amount being redeemed to such Redemption Date.

     “Treasury Rate” means, with respect to any Redemption Date for the Securities of this series,
(i) the yield, under the heading which represents the average for the immediately preceding week,
appearing in the most recently published statistical release designated “H.15(519)” or any
successor publication which is published weekly by the Board of Governors of the Federal Reserve
System and which establishes yields on actively traded United States Treasury securities adjusted
to constant maturity under the caption “Treasury Constant Maturities,” for the maturity
corresponding to the Comparable Treasury Issue (if no maturity is

C-2

 

within three months before or after the Stated Maturity, yields for the two published
maturities most closely corresponding to the Comparable Treasury Issue shall be determined, and the
Treasury Rate shall be interpolated or extrapolated from such yields on a straight-line basis,
rounding to the nearest month) or (ii) if such release (or any successor release) is not published
during the week preceding the calculation date or does not contain such yields, the rate per annum
equal to the semi-annual equivalent yield to maturity of the Comparable Treasury Issue, calculated
using a price for the Comparable Treasury Issue (expressed as a percentage of its principal amount)
equal to the Comparable Treasury Price for such Redemption Date. The Treasury Rate shall be
calculated on the third Business Day preceding the Redemption Date.

     “Comparable Treasury Issue” means the United States Treasury security selected by the
Quotation Agent as having a maturity comparable to the remaining term of the Securities of this
series to be redeemed that would be utilized, at the time of selection and in accordance with
customary financial practice, in pricing new issues of corporate debt securities of comparable
maturity to the remaining term of such Securities of this series.

     “Quotation Agent” means a Reference Treasury Dealer appointed by the Corporation.

     “Comparable Treasury Price” means with respect to any Redemption Date for the Securities of
this series, (1) the average of three Reference Treasury Dealer Quotations for such Redemption
Date, after excluding the highest and lowest such Reference Treasury Dealer Quotations, or (2) if
fewer than three such Reference Treasury Dealer Quotations are obtained, the average of all such
Reference Treasury Dealer Quotations.

     “Reference Treasury Dealer” means each of Credit Suisse Securities (USA) LLC, Goldman, Sachs &
Co., and Lehman Brothers Inc., and their respective successors; provided, however, that if any of
the foregoing ceases to be a primary U.S. Government securities dealer in the United States (a
“Primary Treasury Dealer”), the Corporation will substitute therefor another Primary Treasury
Dealer.

     “Reference Treasury Dealer Quotations” means, with respect to each Reference Treasury Dealer
and any Redemption Date, the average, as determined by the Quotation Agent, of the bid and asked
prices for the Comparable Treasury Issue (expressed in each case as a percentage of its principal
amount) quoted in writing to the Quotation Agent by such Reference Treasury Dealer at 5:00 p.m.,
New York City time, on the third Business Day preceding such Redemption Date.

     The Corporation shall notify the Trustee of the Redemption Price with respect to the foregoing
redemption promptly after the calculation thereof. The Trustee shall not be responsible for
calculating said Redemption Price.

     Notice of any redemption by the Corporation will be mailed at least 30 days but not more than
60 days before any Redemption Date to each Holder of Securities of this series to be redeemed. If
Notice of a redemption is provided and funds are deposited as required, interest will cease to
accrue on and after the Redemption Date on the Securities of this series or portions of Securities
of this series called for redemption. In the event that any Redemption Date is not a Business Day,
the Corporation will pay the Redemption Price on the next Business Day without any interest or
other payment in respect of any such delay. If less than all the Securities of this

C-3

 

series are to be redeemed at the option of the Corporation, the Trustee shall select, in such
manner as it shall deem fair and appropriate, the Securities of this series to be redeemed in whole
or in part. The Trustee may select for redemption Securities of this series and portions of the
Securities of this series in amounts of $2,000 or any integral multiple of $1,000 in excess
thereof.

     In the event of redemption of this Security in part only, a new Security or Securities of this
series and of like tenor for the unredeemed portion hereof will be issued in the name of the Holder
hereof upon the surrender hereof.

     The Securities of this series shall not have a sinking fund.

     The Securities of this series shall constitute the direct unsecured and unsubordinated debt
obligations of the Corporation and shall rank equally in priority with the Corporation’s existing
and future unsecured and unsubordinated indebtedness.

     REFERENCE IS HEREBY MADE TO THE FURTHER PROVISIONS OF THIS SECURITY SET FORTH ON THE REVERSE
HEREOF, WHICH FURTHER PROVISIONS SHALL FOR ALL PURPOSES HAVE THE SAME EFFECT AS IF SET FORTH AT
THIS PLACE.

     Unless the certificate of authentication hereon has been executed by the Trustee by manual
signature, this Security shall not be entitled to any benefit under the Indenture or be valid or
obligatory for any purpose.

C-4

 

     IN WITNESS WHEREOF, the Corporation has caused this instrument to be duly executed.

	 	 	 	 	 
	 	Duke Energy Corporation

 	 
	 	By:  	 	 
	 	 	Name:  	M. Allen Carrick 	 
	 	 	Title:  	Assistant Treasurer 	 
	 

CERTIFICATE OF AUTHENTICATION

     This is one of the Securities of the series designated therein referred to in the
within-mentioned Indenture.

	 	 	 	 	 
	 	The Bank of New York Trust Company, N.A.,

as Trustee

 
	 
	 	By:  	 	 
	 	 	Authorized Signatory 	 
	 	 	 	 
	 

C-5

 

(Reverse Side of Security)

     This 6.25% Senior Note due 2018 is one of a duly authorized issue of Securities of the
Corporation (the “Securities”), issued and issuable in one or more series under an Indenture, dated
as of June 3, 2008, as supplemented (the “Indenture”), between the Corporation and The Bank of New
York Trust Company, N.A., as Trustee (the “Trustee,” which term includes any successor trustee
under the Indenture), to which Indenture and all indentures supplemental thereto reference is
hereby made for a statement of the respective rights, limitation of rights, duties and immunities
thereunder of the Corporation, the Trustee and the Holders of the Securities issued thereunder and
of the terms upon which said Securities are, and are to be, authenticated and delivered. This
Security is one of the series designated on the face hereof as 6.25% Senior Notes due 2018
initially in the aggregate principal amount of $250,000,000. Capitalized terms used herein for
which no definition is provided herein shall have the meanings set forth in the Indenture.

     If an Event of Default with respect to the Securities of this series shall occur and be
continuing, the principal of the Securities of this series may be declared due and payable in the
manner, with the effect and subject to the conditions provided in the Indenture.

     The Indenture permits, with certain exceptions as therein provided, the amendment thereof and
the modification of the rights and obligations of the Corporation and the rights of the Holders of
the Securities of all series affected under the Indenture at any time by the Corporation and the
Trustee with the consent of the Holders of not less than a majority in principal amount of the
Outstanding Securities of all series affected thereby (voting as one class). The Indenture contains
provisions permitting the Holders of not less than a majority in principal amount of the
Outstanding Securities of all series with respect to which a default under the Indenture shall have
occurred and be continuing (voting as one class), on behalf of the Holders of the Securities of all
such series, to waive, with certain exceptions, such default under the Indenture and its
consequences. The Indenture also permits the Holders of not less than a majority in principal
amount of the Securities of each series at the time Outstanding, on behalf of the Holders of all
Securities of such series, to waive compliance by the Corporation with certain provisions of the
Indenture affecting such series. Any such consent or waiver by the Holder of this Security shall be
conclusive and binding upon such Holder and upon all future Holders of this Security and of any
Security issued upon the registration of transfer hereof or in exchange hereof or in lieu hereof,
whether or not notation of such consent or waiver is made upon this Security.

     No reference herein to the Indenture and no provision of this Security or of the Indenture
shall alter or impair the obligation of the Corporation, which is absolute and unconditional, to
pay the principal of and interest on this Security at the times, place and rate, and in the coin or
currency, herein prescribed.

     As provided in the Indenture and subject to certain limitations therein set forth, the
transfer of this Security is registrable in the Security Register, upon surrender of this Security
for registration of transfer at the office or agency of the Corporation for such purpose, duly
endorsed by, or accompanied by a written instrument of transfer in form satisfactory to the
Corporation and the Security Registrar and duly executed by, the Holder hereof or his attorney duly
authorized in writing, and thereupon one or more new Securities of this series, of authorized

C-6

 

denominations and of like tenor and for the same aggregate principal amount, will be issued to
the designated transferee or transferees. No service charge shall be made for any such registration
of transfer or exchange, but the Corporation may require payment of a sum sufficient to cover any
tax or other governmental charge payable in connection therewith.

     The Indenture contains provisions for defeasance at any time of the entire indebtedness of the
Securities of this series and for covenant defeasance at any time of certain covenants in the
Indenture upon compliance with certain conditions set forth in the Indenture.

     Prior to due presentment of this Security for registration of transfer, the Corporation, the
Trustee and any agent of the Corporation or the Trustee may treat the Person in whose name this
Security is registered as the owner hereof for all purposes, whether or not this Security be
overdue, and neither the Corporation, the Trustee nor any such agent shall be affected by notice to
the contrary.

     The Securities of this series are issuable only in registered form without coupons in
denominations of $2,000 or any integral multiple of $1,000 in excess thereof. As provided in the
Indenture and subject to the limitations therein set forth, Securities of this series are
exchangeable for a like aggregate principal amount of Securities of this series of a different
authorized denomination, as requested by the Holder surrendering the same upon surrender of the
Security or Securities to be exchanged at the office or agency of the Corporation.

     This Security shall be governed by, and construed in accordance with, the laws of the State of
New York.

C-7

 

ABBREVIATIONS

     The following abbreviations, when used in the inscription on the face of this instrument,
shall be construed as though they were written out in full according to applicable laws or
regulations:

	 	 	 	 	 	 	 	 	 
	TEN COM—as tenants in common

	 	UNIF GIFT MIN ACT-
	 	 	 	Custodian	 	 
	 

	 	 	 	 

(Cust)
	 	 	 	 

(Minor)

TEN ENT—as tenants by the entireties

	 	 	 	 	 	 	 
	JT TEN—as joint tenants with rights of	 	under Uniform Gifts to	 	 
	survivorship and not as tenants in common
	 	Minors Act 	 	 	 	 
	 
	 	 	
 

(State)	 	 

Additional abbreviations may also be used though not on the above list.

FOR VALUE RECEIVED, the undersigned hereby sell(s) and transfer(s) unto (please insert Social
Security or other identifying number of assignee)

PLEASE PRINT OR TYPEWRITE NAME AND ADDRESS, INCLUDING POSTAL ZIP CODE OF ASSIGNEE

the within Security and all rights thereunder, hereby irrevocably constituting and appointing agent
to transfer said Security on the books of the Corporation, with full power of substitution in the
premises.

Dated:                                         

	 	 	 
	 

	 	NOTICE: The signature to this assignment must
correspond with the name as written upon the face of
the within instrument in every particular without
alteration or enlargement, or any change whatever.
	 
	 	 
	 

	 	Signature Guarantee:                                                             

C-8

 

SIGNATURE GUARANTEE

     Signatures must be guaranteed by an “eligible guarantor institution” meeting the requirements
of the Security Registrar, which requirements include membership or participation in the Security
Transfer Agent Medallion Program (“STAMP”) or such other “signature guarantee program” as may be
determined by the Security Registrar in addition to, or in substitution for, STAMP, all in
accordance with the Securities Exchange Act of 1934, as amended.

C-9

 

EXHIBIT D

CERTIFICATE OF AUTHENTICATION

     This is one of the Securities of the series designated therein referred to in the
within-mentioned Indenture.

	 	 	 	 	 
	 	The Bank of New York Trust Company, N.A.,

as Trustee

 
	 
	 	By:  	 	 
	 	 	Authorized Signatory 	 
	 	 	 	 
	 

D-1Confidential
CERTAIN PORTIONS OF THIS EXHIBIT HAVE BEEN OMITTED PURSUANT TO RULE 24B-2 AND
ARE SUBJECT TO A CONFIDENTIAL TREATMENT REQUEST. COPIES OF THIS EXHIBIT
CONTAINING THE OMITTED INFORMATION HAVE BEEN FILED SEPARATELY WITH THE
SECURITIES AND EXCHANGE COMMISSION. THE OMITTED PORTIONS OF THIS DOCUMENT ARE
MARKED WITH A [***].

                                                                   Exhibit 10.1

                          RESEARCH AND OPTION AGREEMENT

         This Research and Option Agreement ("Agreement") is effective as of May
16, 2008 (the "Effective Date") by and between Accelr8 Technology Corporation,
having a place of business at 7000 North Broadway, Building 3-307, Denver,
Colorado 80221 ("Accelr8"), and Becton, Dickinson and Company, a corporation
organized under the laws of the State of New Jersey, having a place of business
at 1 Becton Drive, Franklin Lakes, New Jersey 07417, for itself ("BD"). BD and
Accelr8 are together hereinafter collectively referred to as the "Parties" and
individually referred to as a "Party".

         WHEREAS, Accelr8 has a technology platform directed to, among other
things, infectious disease identification and antimicrobial susceptibility or
resistance testing;

         WHEREAS, BD makes and sells products for diagnostic purposes,
including, among other things, infectious disease identification and
antimicrobial susceptibility or resistance testing; and

         WHEREAS, BD is interested in funding research work by Accelr8 in order
to assess the capabilities of Accelr8's technology platform, and assess BD's
interest in licensing Accelr8's technology (such assessments collectively the
"Stated Purpose").

         NOW, THEREFORE, in consideration of the mutual promises and other good
and valuable consideration, the receipt and sufficiency of which is hereby
acknowledged, the Parties agree as follows:

1        DEFINITIONS

     A. "Accelr8 Background IP" shall mean, collectively, the Accelr8 Background
     Know-How and the Accelr8 Background Patent Rights

     B. "Accelr8 Background Know-How" shall mean any and all technical and other
     information, in existence as of October 31, 2009 which is not in the public
     domain and which is not embodied in a patent, (i) relating to the BACcel
     Platform or (ii) which is reasonably necessary to enable BD and its
     Affiliates to commercially exploit the rights granted to BD and its
     Affiliates by Accelr8. Accelr8 Background Know-How does not include Program
     IP.

     C. "Accelr8 Background Patent Rights" shall mean and collectively include
     (a) the patents and patent applications in Appendix D; (b) any other
     patents or patent applications now or in the future owned or Controlled by

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     Accelr8 directed to the BACcel Platform and applicable in the Field, other
     than Program IP; (c) all U.S., foreign, and international patent
     applications that claim priority to, are entitled to claim priority to,
     rely for priority on, or to which priority is claimed by, the foregoing
     patents or patent applications; (d) any reissues, reexaminations,
     extensions, substitutions, divisions, continuations and
     continuations-in-part of the foregoing; and (e) all patents that issue from
     any of the foregoing, and any reissues, reexaminations and extensions
     thereof.

     D. "Affiliates" shall mean any corporation or other business entity which
     controls, is controlled by, or is under common control with, a Party. For
     purposes of this Article 1D, "control" means direct or indirect ownership
     of (i) at least fifty percent (50%) of the outstanding stock or of the
     other voting rights entitled to elect directors, or (ii) in any country
     where the local law shall not permit foreign equity participation of at
     least fifty percent 50%, then the maximum percentage of such outstanding
     stock or voting rights permitted by local law.

     E. "BACcel Platform" shall mean the technology embodied in Accelr8's
     BACcel(TM) system as of the Effective Date, or technology for processes or
     systems (or components thereof) directed to one or more of the following:

          i) concentration of live bacteria onto a surface,
          ii) immobilization of such bacteria on such surface,
          iii) mapping individual bacterium locations on the surface,
          iv) identifying such immobilized bacteria,
          v) testing antimicrobial susceptibility or antimicrobial resistance
          testing of such immobilized bacteria,
          vi) testing other characteristics or properties of such immobilized
          bacteria, and
          vii) use of microscopy and/or image analysis to perform the mapping,
          identifying and/or testing steps.

     F. "BD Background IP" shall mean any intellectual property, including
     patents, patent applications, inventions, innovations, techniques, trade
     secrets, discoveries, technologies, software or know-how made, developed,
     owned, licensed or acquired by BD and its Affiliates before the Effective
     Date of this Agreement or during the term of the Agreement.

     G. "Confidential Information" shall mean and include all proprietary
     information, including, without limitation, Accelr8 Background IP, BD
     Background IP and the results of the Research Program, that is disclosed by
     one Party or its Affiliate to the other Party or its Affiliate in
     connection with this Agreement and the Research Program, the Exclusive
     License Agreement or the Non-Exclusive License Agreement, which is
     designated in writing whether by letter or by the use of an appropriate
     stamp or legend such as "confidential," "proprietary," or "sensitive" by
     the disclosing Party prior to or at the time of disclosure, which is orally
     or visually disclosed and indicated to be proprietary at the time of
     disclosure, or which is of a nature such that the receiving party would
     reasonably treat such information as proprietary. The terms of this
     Agreement and any related agreements between the Parties shall also be
     considered Confidential Information.

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     H. "Control" or "Controlled" shall mean with respect to a particular item
     of intellectual property, the ability to grant access to or a license or
     sublicense under such item as set forth for herein, without violating the
     terms of any agreement or other arrangement with, or the right of, any
     third party.

     I. "Exclusive License Agreement" shall mean the license agreement attached
     hereto as Appendix B.

     J. "Field" shall mean products or processes for Infectious Disease
     Diagnostics.

     K. "Infectious Disease Diagnostics" shall mean activities directed to the
     presence or absence of diseases in humans that are caused by one or more
     infectious agents, non-infectious carriers or bioproducts of agents or
     carriers, such activities including but not limited to, screening,
     monitoring, detecting, identifying, diagnosing and/or prognosing such
     diseases, as well as performing epidemiological analyses of such diseases.
     By way of example, Infectious Disease Diagnostics shall include but not be
     limited to: (a) measuring or monitoring one or more markers associated with
     an infectious agent, (b) measuring or monitoring one or more surrogate
     markers (including host response markers) indicative of the presence of an
     infectious agent or of a disease caused by an infectious agent, (c)
     identification of an infectious agent, (d) identification of antimicrobial
     resistance mechanisms or antimicrobial resistance markers of an infectious
     agent, and (e) identification of antimicrobial susceptibility of an
     infectious agent.

     L. "Non-Exclusive License Agreement" shall mean the license agreement
     attached hereto as Appendix C. M. "Option Date" shall mean the later of
     October 31, 2009 or thirty (30) days after completion of the Research
     Program.. N. "Program IP" shall mean any intellectual property, including
     patents, patent applications, inventions, innovations, techniques, trade
     secrets, discoveries, technologies, software or know-how conceived or
     reduced to practice solely by employees of Accelr8 or jointly by employees
     of BD or a BD Affiliate and Accelr8 in the course of performing the
     Research Program, including improvements or modifications to Accelr8
     Background IP. O. "Research Program" shall mean the research and
     development program set forth in Appendix A attached hereto and hereby
     incorporated by reference.

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2 RESEARCH PROGRAM

     A. The Parties shall perform their respective obligations under the
     Research Program. In case of any dispute over whether the Research Program
     has been completed, the Party's disagreement shall be submitted to binding
     arbitration in New York City. The arbitration shall be conducted in
     accordance with the Commercial Arbitration Rules of the American
     Arbitration Association ("AAA"), except as set forth in this Section. Each
     Party shall bear its own costs. The arbitration shall be governed by the
     substantive laws of the State of New Jersey, without regard to
     conflicts-of-law rules, and by the arbitration law of the Federal
     Arbitration Act (Title 9, U.S. Code). Judgment upon the award rendered may
     be entered in any court having jurisdiction. Should arbitration result in a
     judgment that the Research Program had been completed, the Option Date
     shall be thirty (30) days after the date of such judgment.

     B. The Research Program shall be under the joint supervision of an
     individual to be named by BD and an individual to be named by Accelr8
     ("Principal Collaborators").

     C. The Research Program described in Appendix A can only be changed or
     extended by written agreement between the Parties.

     D. BD shall make payments to Accelr8 under this Agreement, upon receipt of
     an invoice from Accelr8, as follows:

          o    $[***] upon execution of this Agreement
          o    $[***] on July 1, 2008
          o    $[***] on October 1, 2008
          o    $[***] on January 1, 2009
          o    $[***] on April 2, 2009
          o    $[***] on July 1, 2009

     E. The Parties shall keep each other fully informed of the progress of the
     Research Program through regular meetings, telephone conferences and/or
     electronic mail, or as otherwise set forth in the Research Program or as
     otherwise requested by either Party.

     F. Subject to the exclusivity provisions of Article 3 and subject to
     Article 4B, each Party acknowledges that the other Party may at its sole
     discretion conduct research outside of the Research Program, and that such
     research is not subject to this Agreement.

     G. Provided Accelr8 has made good faith efforts to complete the Research
     Program, BD's and BD Affiliate's sole remedy and Accelr8's exclusive
     liability for any breach of Accelr8's failure to complete the Research
     Program shall be re-performance of the relevant tasks. THE RESEARCH PROGRAM
     IS PERFORMED ON AN AS-IS BASIS, AND ACCELR8 DISCLAIMS ALL WARRANTIES,

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     INCLUDING THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A
     PARTICULAR PURPOSE. IN NO EVENT WILL ACCELR8 BE LIABLE FOR ANY INCIDENTAL,
     SPECIAL OR CONSEQUENTIAL DAMAGES RESULTING FROM PERFORMANCE UNDER THIS
     AGREEMENT.

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3  EXCLUSIVITY

     A. From the Effective Date of the Agreement until the earlier of the Option
     Date or the date of early termination if any, Accelr8 shall not, directly
     or indirectly, solicit, initiate, facilitate, encourage or participate in
     any discussions or negotiations with parties other than BD or BD
     Affiliates, directed to (i) joint development or other collaborative
     activity with such third party relating to the BACcel Platform in the
     Field, with the exception of contracted research with non-commercial
     laboratories or submission for grants from non-commercial institutions or
     agencies, provided such work does not in any way interfere with the rights
     granted in the Agreement, the ELA or the NELA, as applicable; or (ii)
     licensing of Accelr8 Background IP, or other intellectual property relating
     to the BACcel Platform, in the Field, or (iii) any other activity that
     might affect BD's rights as set forth in this Agreement, and Accelr8
     further represents that it is not currently involved in any of the
     activities set forth in (i) through (iii) as of the Effective Date of the
     Agreement.

4 CONFIDENTIALITY

     A. In the performance of the Research Program, it may be necessary for the
     Parties to disclose Confidential Information to each other.

     B. Confidential Information shall be maintained by the receiving Party as
     confidential, using the same care and discretion that the receiving Party
     uses with its own Confidential Information, but, in any event, no less than
     a reasonable degree of care. Subject to Article 6, Confidential
     Information: (a) shall remain the exclusive property of the disclosing
     Party, (b) will be used by the receiving Party solely for the Stated
     Purpose; and (c) will not be disclosed by the receiving Party to any other
     persons or entities, except its employees on a need-to-know basis, unless
     written permission is obtained in advance from the disclosing Party.

     C. Notwithstanding the foregoing, or any other provision contained herein
     to the contrary, the receiving Party's obligations under Article 4B shall
     not apply to the extent that the receiving Party can prove by written
     evidence that the respective Confidential Information:

          (i) was known by a Party at or prior to the Effective Date of this
          Agreement, except to the extent unlawfully appropriated by a Party; or

          (ii) is or becomes generally known in the trade or business pertaining
          to such information or otherwise becomes publicly known at or after
          the time of disclosure by the disclosing Party, through no wrongful
          act of the receiving Party; or

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          (iii) is rightfully received by a Party from a third party without
          restriction and without breach of this Agreement; or (iv) is developed
          by a Party independent of any Confidential Information of the other
          Party, such independent development being performed solely by persons
          not having access whatsoever to the other Party's Confidential
          Information; or

          (v) is required to be disclosed by a court or judicial or governmental
          authority of competent jurisdiction, and in such event, only after the
          Party required to disclose the other Party's Confidential Information
          provides prompt written notice to that Party so as to enable that
          Party to resist any such required disclosure and/or to obtain suitable
          protection regarding such required disclosure.

     D. The foregoing provisions and obligations of this Article 4 shall remain
     in effect and survive for five (5) years after termination or expiration of
     this Agreement, except that trade secrets designating in writing as such by
     the disclosing party shall remain secret subject to Article 4C and
     applicable laws.

5 PUBLICATION

     A. Accelr8, BD, and BD Affiliates shall not have the right to publish or
     publicly present any of the research and development activities in
     connection with and/or results of the Research Program without the written
     approval of the other Party ("the second Party") with the exception of
     collaborations with non-commercial laboratories that have agreements in
     place as of the Effective Date, where such agreements contain provisions
     allowing publications, provided such publication does not in any way
     interfere with the rights and obligations set forth in the Agreement, the
     Exclusive License Agreement or the Non-Exclusive License Agreement, as
     applicable.

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6  OPTION AND INTELLECTUAL PROPERTY

     A. From the Effective Date through the date that is the earlier of: the
     Option Date or the date at which BD exercises the Option pursuant to
     Article 6D, intellectual property rights and ownership shall be as follows:

          i) Program IP shall be jointly owned by the Parties, but neither party
          may use such Program IP other than for purposes of this Agreement in
          the Field. Program IP conceived or reduced to practice solely by
          employees of Accelr8 shall be assigned to Accelr8, which shall then
          assign an undivided half-interest in such Program IP to BD, subject to
          the terms of this Agreement. Program IP conceived or reduced to
          practice by employees of Accelr8 and employees of BD or BD Affiliates
          shall be jointly assigned.

          ii) Accelr8 Background IP shall remain the property of Accelr8, and BD
          or BD Affiliates shall have no rights thereunder.

          iii) BD Background IP shall remain the property of BD and/or BD
          Affiliates, and Accelr8 shall have no rights thereunder.

          iv) The Parties agree to cooperate in identifying Program IP. The
          Parties shall share the costs and expenses 50/50 in preparing, filing,
          prosecuting, maintaining and extending patents and patent applications
          directed to Program IP using counsel reasonably agreeable to both
          parties.

          v) The Parties agree to cooperate fully in providing information and
          executing all documents needed to prepare, file and prosecute any
          patent application hereunder.

     B. Accelr8 hereby grants BD an option ("Option") to take an exclusive
     license to Accelr8 Background IP in the Field. i) The Option shall exist
     from the Effective Date up to and including the Option Date. BD shall have
     the right to exercise the Option upon written notice to Accelr8.

          ii) If BD exercises the Option:

               (a) BD shall make a single, lump sum payment of [***] dollars
               ($[***]) to Accelr8 within thirty (30) days of the written
               notice, which shall not be creditable against running royalties
               due under the Exclusive License Agreement; and

               (b) The Exclusive License Agreement attached hereto as Appendix B
               shall immediately come into effect upon (i) Accelr8's receipt of
               the payment under Article 6B(ii)(a), and (ii) Accelr8's receipt
               of cumulative payments of [***] Dollars ($[***]) under Article
               2D.

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          iii) If BD does not exercise the Option:

               (a) No additional payment to Accelr8 is required, beyond those
               set forth in Article 2 of this Agreement; and

               (b) The Non-Exclusive License Agreement attached hereto as
               Appendix C shall immediately come into effect the day after the
               Option Date, and the Exclusive License Agreement attached hereto
               as Appendix B shall become null and void.

          iv) If Accelr8 has not completed the Research Program, by October 31,
          2009, then at any time after October 31, 2009, BD shall have the right
          to decline the Option upon written notice to Accelr8. Should BD
          decline the Option:

               (a) No additional payment to Accelr8 is required, beyond those
               set forth in Article 2 of this Agreement; and

               (b) The Non-Exclusive License Agreement attached hereto as
               Appendix C shall immediately come into effect upon receipt of the
               written notice by Accelr8, and the Exclusive License Agreement
               attached hereto at Appendix B shall become null and void.

7 TERM and TERMINATION

     A. This Agreement shall become effective as of the Effective Date and shall
     terminate upon the Exclusive License Agreement or the Non-Exclusive License
     Agreement coming into effect pursuant to Article 6, unless terminated
     earlier under this Article 7.

     B. This Agreement shall be terminable upon the material breach or default
     of either Party. In the event of a material breach or default by a Party
     ("Defaulting Party"), the other Party ("non-Defaulting Party") shall give
     the Defaulting Party written notice of the default and its election to
     terminate this Agreement effective at the expiration of a period of sixty
     (60) days from the date of the notice. If the Defaulting Party fails to
     resolve the default in the probation period by (i) curing the default, (ii)
     providing a written explanation satisfactory to the Non-Defaulting Party
     that a default has not occurred, or (iii) entering into a written agreement
     with the Non-Defaulting Party for the cure or other resolution of the
     default, then this Agreement shall terminate upon the expiration of such
     sixty (60) day period. All termination rights shall be in addition to and
     not in substitution for any other remedies that may be available to the
     Non-Defaulting Party. Termination pursuant to this Article shall not
     relieve the Defaulting Party from liability and damages to the
     Non-Defaulting Party for default.

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          i) Upon termination by BD for Accelr8's material breach, the Option
          shall remain in effect for thirty (30) days after termination of the
          Agreement, and either the Exclusive License Agreement or Non-Exclusive
          License Agreement shall then come into force and effect, as
          applicable.

          ii) Upon termination by Accelr8 for BD's material breach, the Option
          shall terminate upon termination of the Agreement, and the
          Non-Exclusive License Agreement shall then come into force and effect.

     C. Any termination of this Agreement for any reason does not relieve either
     Party of any obligation or liability accrued prior to the termination or
     rescind anything done by either Party and the termination does not affect
     in any manner any rights of either Party arising under this Agreement prior
     to the termination.

     D. The terms and conditions of the following provisions shall survive
     termination or expiration of this Agreement for as long as necessary to
     permit their full discharge: Articles 4 (CONFIDENTIALITY), 5 (PUBLICATION),
     6 (OPTION AND INTELLECTUAL PROPERTY), 8 (USE OF NAMES), 9 (NOTICES), 11
     (RIGHTS NOT GRANTED), 13 (GOVERNING LAW) and 15 (MISCELLANEOUS).

8 USE OF NAMES

     A. Neither Party shall use the name of the other Party or any adaptation
     thereof in any publication, advertising, promotion, sales literature or
     packaging without the prior written consent of the other Party. Any press
     release, public announcement or similar publicity by the Parties with
     respect to this Agreement shall be subject to the prior consent of the
     other Party, which consent shall not be unreasonably withheld, unless such
     communication is required to be made by law or pursuant to the rules and
     regulations of the Securities and Exchange Commission or the New York Stock
     Exchange listing requirements or an equivalent agency and after
     consultation and coordination between the Parties. Such press release,
     public announcement or similar publicity shall be limited to the existence
     of the Agreement and shall not disclose the terms thereof. In the case of
     required communication to agencies such as listed above, the terms of the
     Agreement shall be redacted unless prohibited by applicable laws or rules.

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9 NOTICES

     A. Any notices required to be given or which shall be given under this
     Agreement shall be in writing delivered by certified return-receipt
     requested first-class mail or overnight courier with tracking or facsimile
     addressed to the Parties as follows:

              For BD:
              Becton, Dickinson and Company
              7 Loveton Circle
              Sparks, Maryland 21152
              Fax: 410-316-4081
              Attention: Director / Strategic Planning and Business Development

              with a copy to :
              Becton, Dickinson and Company
              1 Becton Drive  MC089
              Franklin Lakes, NJ  07417
              Fax:  (201) 848-9228
              Attention:  Vice President, Chief Intellectual Property Counsel

              For Accelr8:
              Accelr8 Technology Corporation
              7000 North Broadway
              Bldg. 3-307 Denver, Colorado 80221 Fax: 303-863-1218
              Attention: Thomas V. Geimer, Chairman and CEO

10 INDEPENDENT PARTIES

     A. For purposes of this Agreement the Parties hereto shall be independent
     contractors and neither shall at any time be considered an agent or an
     employee of the other. No joint venture, partnership or like relationship
     is created between the Parties by this Agreement.

11 RIGHTS NOT GRANTED

     A. Except as explicitly set forth herein, no other rights or licenses in or
     to the BD Background IP, Accelr8 Background IP or Program IP are granted by
     this Agreement.

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12  ASSIGNMENT

     A. Any assignment by either Party without prior written consent of the
     other Party shall be void.

     B. The provisions of the Agreement shall be binding upon and inure to the
     benefit of the Parties and the respective successors and assigns of each of
     the Parties. To the extent permitted by law, if any Party hereto ("Bankrupt
     Party") shall become insolvent, or shall suspend business or shall file a
     voluntary petition or answer admitting the jurisdiction of the Court or the
     material allegations of a petition, or shall consent to an involuntary
     petition pursuant to or purporting to be pursuant to any reorganization or
     insolvency law of any jurisdiction, or shall make an assignment for the
     benefit of creditors, or shall apply for or consent to the appointment of a
     receiver or trustee of a substantial part of its property ("Bankruptcy
     Event"), then it is the Parties' intent that this Agreement and the rights
     granted to BD hereunder by the Bankrupt Party must be adopted by any
     bankruptcy trustee or relevant third Party charged with the disposition of
     same, and cannot be rejected. The Parties acknowledge that this Agreement
     contemplates the manner in which the Parties may retain the rights granted
     to them hereunder by the Bankrupt Party, if they choose to do so in
     accordance with Section 365(n) of the Bankruptcy Code. It is the Parties'
     intent that, upon the occurrence of any Bankruptcy Event, BD shall be
     entitled to retain the rights granted to them hereunder by the Bankrupt
     Party in all items delivered or required to be delivered under this
     Agreement.

13 GOVERNING LAW

     A. This Agreement shall be interpreted and construed in accordance with the
     laws of the State of New Jersey, without reference to choice of law
     doctrine.

14 FORCE MAJEURE

     A. Except as provided below, no failure or omission by a Party (the
     "Affected Party") in the performance of any obligation of this Agreement
     shall be deemed a breach of this Agreement nor create any liability to the
     other Party (the "Unaffected Party") if such failure or omission shall
     arise from any cause or causes beyond the reasonable control of the
     Affected Party; including, without limitation, the following: acts of God;
     fire; storm; flood; earthquake; war; sabotage; quarantine restrictions;
     government action; labor strike or freight embargo (hereinafter "Force
     Majeure"). In the event of any delay or inability to perform arising

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     pursuant to Force Majeure, the Affected Party's performance shall be
     postponed by such length of time (the "Suspension Period") as may be
     reasonably necessary to compensate for said delay or inability to perform,
     and the Unaffected Party's performance shall likewise be postponed by a
     length of time equal to the Suspension Period. In the event a Force Majeure
     shall suspend the Affected Party's obligations hereunder for more than
     ninety (90) days, the Unaffected Party shall have the right to terminate
     this Agreement, with no further payments due under Articles 2D. Upon such
     termination, the Non-Exclusive License Agreement shall come into force and
     effect.

15 MISCELLANEOUS

     A. The Parties agree that the terms of this Agreement are binding upon them
     as well as any of their respective employees who may assist in the Research
     Program.

     B. The Parties represent and warrant that they are not under obligation to
     any third party that would interfere with the rendering of services to the
     other Party or which would be inconsistent with any responsibilities or
     obligations (including rights granted) under this Agreement.

     C. The provisions of this Agreement shall not be extended, varied, changed,
     modified or supplemented other than by agreement in writing signed by the
     Parties hereto.

     D. The headings used herein are for ease of reference only and are not to
     be used in the interpretation or construction of this Agreement.

     E. If and to the extent any court of competent jurisdiction shall hold any
     provision (or any part thereof) of this Agreement to be invalid or
     unenforceable, such holding shall in no way affect the validity of the
     remainder of this Agreement.

     F. Except as otherwise provided herein, the failure of a Party hereto to
     enforce any of the provisions of this Agreement or any rights with respect
     thereto or to exercise any election provided for herein, shall in no way be
     considered a waiver of such provisions, rights or elections or in any way
     affect the validity of this Agreement. No term or provision hereof shall be
     deemed waived and no breach excused, unless such waiver or consent shall be
     in writing and signed by the Party claimed to have so waived or consented.

     G. In case of a conflict between the terms of this Agreement and either the
     Exclusive License Agreement or the Non-Exclusive License Agreement, the
     applicable License Agreement shall govern.

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         IN WITNESS WHEREOF, the persons executing this Agreement in duplicate
originals, on behalf of the Parties hereto, represent and warrant, that they are
duly authorized officers and representatives and have authority to execute such
Agreement on behalf on their respective Party.

ACCELR8 TECHNOLOGY CORPORATION             BECTON, DICKINSON AND COMPANY

By:  _________________________             By: _________________________________
           Thomas V. Geimer                           Philippe Jacon
           Chairman and CEO                  President - Microbiology Systems
                                                     BD Diagnostics

                                           Date:
Date:

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                          Appendix A - Research Program

                               [***][1 page total]

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CERTAIN PORTIONS OF THIS EXHIBIT HAVE BEEN OMITTED PURSUANT TO RULE 24B-2 AND
ARE SUBJECT TO A CONFIDENTIAL TREATMENT REQUEST. COPIES OF THIS EXHIBIT
CONTAINING THE OMITTED INFORMATION HAVE BEEN FILED SEPARATELY WITH THE
SECURITIES AND EXCHANGE COMMISSION. THE OMITTED PORTIONS OF THIS DOCUMENT ARE
MARKED WITH A [***].

                                   Appendix B
                                   ----------

                           EXCLUSIVE LICENSE AGREEMENT

         This Exclusive License Agreement ("ELA") is made and entered into
effective pursuant to Article 6 of the Agreement ("ELA Effective Date"), by and
between Accelr8 Technology Corporation, having a place of business at 7000 North
Broadway, Building 3-307, Denver, Colorado 80221, ("Accelr8") and Becton,
Dickinson and Company, a corporation duly organized under the laws of the State
of New Jersey and having its principal office in 1 Becton Drive Franklin Lakes,
NJ 07417 for itself and its Affiliates ("BD"), (each a "Party" and collectively
the "Parties").

                                   WITNESSETH
                                   ----------

         WHEREAS, the Parties entered into a Research and Option Agreement
("Agreement") effective May 16, 2008 to which this ELA is attached;

         WHEREAS, Article 6 of the Agreement provided BD with the Option for an
exclusive license to certain Accelr8 intellectual property; and

         WHEREAS, the Parties agreed that upon exercise of the Option, this ELA
would immediately come into force and effect;

         NOW, THEREFORE, in consideration of the premises and the mutual
covenants contained herein, the Parties hereto agree as follows:

                            ARTICLE 1 - DEFINITIONS
                            -----------------------

         Capitalized terms not defined herein shall have the meaning set forth
in the Agreement. For the purposes of this ELA, the following words and phrases
shall have the following meanings:

         1.1 "Commercial Sales" shall mean any sale of a Licensed Product in any
country in the world, excluding sales for purposes of testing, validation
studies, marketing evaluations or clinical trials, or provided as marketing
samples.

         1.2 "Development Costs" shall mean direct research and product
development expenditure incurred by BD in the research and product development
of a BACcel Platform product. Development Costs shall not include any overhead
expenses, and shall be pro-rated with respect to expenditures applicable both to
the BACcel Platform and to other BD activities. In addition, Development Costs
does not include any amounts paid under the Agreement or any royalties due under
this ELA.

         1.3 "Kit" shall mean a combination product offered or sold by BD that
includes a Licensed Product in combination with identifiable products having a
separate use or purpose not licensed hereunder.

         1.4 "Licensed Product" shall mean collectively any process or product,
the making, using, offering for sale, selling, importing or practice of which
would, but for this ELA, infringe or contribute to infringement of a Valid Claim
of an issued patent within Accelr8 Background Patent Rights, in the country
where such activity takes place.

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         1.5 "Net Sales" shall mean the sum of all amounts invoiced by BD for
the sale, lease, rental or other mode of transfer, whether permanent or
temporary, of a Licensed Product to third parties, less, to the extent not
already reflected in the invoiced amount:

               1.5.1 reasonable cash discounts to purchasers allowed and taken;

               1.5.2 amounts for transportation or shipping charges from the
place of manufacture to the customer's location actually paid by BD;

               1.5.3 taxes and duties imposed on the sale of Licensed Product,
levied and actually paid;

               1.5.4 refunds, rebates, or allowances;

               1.5.5 transfers for non-commercial testing, validation studies,
marketing evaluations and clinical trials; and/or

               1.5.6 free distribution (not in exchange for services or
payments) of Licensed Product used solely as marketing samples to develop or
promote the Licensed Product.

         In the case of sale or other transfer of the Licensed Product as part
         of a Kit, the Net Sales shall be determined as follows: If the Licensed
         Product is also sold separately from the Kit, the Net Sales on which
         the royalty rate is applied shall be an amount equal to the Net Sales
         of the Licensed Product if sold separately in a similar transaction
         involving similar volumes of Licensed Product at about the same time as
         the transaction involving such Kit.

         If the Licensed Product or the identifiable products are not sold
         separately from the Kit, the applicable Net Sales for royalty purposes
         shall be determined by multiplying the Net Sales of the Kit by the
         fraction A/(A+B) where A equals the standard fully absorbed cost to BD
         of the Licensed Product and B equals the fully absorbed cost to BD of
         the remaining products in the Kit, such costs determined by using BD
         standard accounting principles in accordance with generally accepted
         accounting practice.

         In the case where an instrument is placed pursuant to a reagent rental
         agreement or an analogous agreement in which a purchaser is provided an
         instrument for use in conjunction with Licensed Products, including but
         not limited to a service contract in conjunction with the instrument,
         and the costs associated with the placement and use of the instrument
         are not separately billed but instead represent some portion of the
         purchase price of the Licensed Products, then BD shall be entitled to
         reduce the Net Sales of such Licensed Products to allow for deduction
         of instrument-related charges such as interest for the financing of the
         instrument supplied, training, warranty and post-warranty cost of
         instrument service, using BD standard accounting principles in
         accordance with generally accepted accounting practice.

         The term Net Sales in the case of non-cash sales, shall mean the fair
         market value of all equivalent or other consideration received by BD.
         If such fair market value of the non-cash consideration is not readily
         and undisputably ascertainable, the Parties shall discuss in good faith
         the cash value of such non-cash consideration, and payment to Accelr8
         shall be based on such cash value.

         Where the Licensed Product is part of a Research Use Only system that
         incorporates a BD instrument capable of use in other systems, such as a

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         multi-purpose imaging instrument, the applicable Net Sales for such
         system shall be only the Net Sales of any consumables sold with or for
         such system.

         1.6 "Research Purposes" shall mean any and all activities directed to
technology or product research but excluding actual commercial manufacture or
commercial sale of a product.

         1.7 "Valid Claim" shall mean an issued claim of an unexpired patent
which shall not have been withdrawn, canceled or disclaimed or held invalid or
unenforceable in an unappealed or unappealable decision.

                               ARTICLE 2 - GRANT
                                -----------------

         2.1 Accelr8 hereby grants to BD and BD Affiliates a world-wide,
paid-up, exclusive license, including the right to grant sublicenses, under
Accelr8's rights and interest in Program IP, to make, have made, use, practice,
offer for sale, sell, import and otherwise dispose of Licensed Products, and to
otherwise practice Program IP in the Field.

         2.2 Accelr8 hereby grants to BD and BD Affiliates a world-wide,
exclusive license, including the right to grant sublicenses, under Accelr8
Background IP, to make, have made, use, practice, offer for sale, sell, import
and otherwise dispose of Licensed Products, and to otherwise practice Accelr8
Background IP, in the Field. The license shall be royalty-bearing with respect
to Accelr8 Background Patent Rights pursuant to Article 3.1, and shall be
royalty-free with respect to Accelr8 Background Know-How.

         2.3 Accelr8 further grants to BD and BD Affiliates a world-wide,
paid-up, non-exclusive license under Accelr8 Background IP, for Research
Purposes. For purposes of this Article 2.3 only, "commercially exploit" as used
in the definition of Accelr8 Background Know-How shall include research and
development activities directed toward commercial exploitation. For avoidance of
doubt, this Article 2.3 does not provide BD with any rights to commercialize
Licensed Products outside the Field.

         2.4 If BD has not spent at least [***] dollars ($[***]) in Development
Costs ("Minimum Development Cost Commitment") by the date that is three (3)
years from the ELA Effective Date, Accelr8 shall be entitled, upon ninety (90)
days written notice, to convert BD's license grant under Article 2.2 to a
non-exclusive license, unless BD meets the Minimum Development Cost Commitment
during such ninety (90) day period. Upon such conversion: (i) the royalty rate
set forth in Article 3.1 shall be reduced to [***] percent ([***]%), (ii) the
stacking provisions of Article 3.5 shall continue to apply, with the minimum
royalty thereunder reduced to [***] percent ([***]%), and (iii) BD's rights
under Articles 5.6 and 5.7 with respect to Accelr8 Background IP shall cease
(BD's rights under Articles 5.6 and 5.7 with respect to Program IP shall
continue). For avoidance of doubt, monies paid under Article 2D of the Agreement
shall not be credited toward the Minimum Development Cost Commitment. As of the
date of a commercial launch by BD of a BACcel Platform product, Accelr8 shall no
longer have a right to convert the license grant to a non-exclusive license
under this Article 2.4.

         2.5 If BD (i) has not spent at least the Minimum Development Cost
Commitment by the date that is five (5) years from the ELA Effective Date, or
(ii) does not spend at least [***] dollars ($[***]) in annual Development Costs
thereafter until such time as BD enters clinical trials and regulatory review
for a BACcel Platform product (to be pro-rated in the year in which BD enters
such clinical trials and regulatory review), Accelr8 shall be entitled, in its
sole discretion, to terminate this ELA upon ninety (90) days written notice,
unless BD meets the Minimum Development Cost Commitment during such ninety (90)
day period. For avoidance of doubt, monies paid under Article 2D of the

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Agreement shall not be credited toward the Minimum Development Cost Commitment.
As of the date of a commercial launch by BD of a BACcel Platform product,
Accelr8 shall no longer have a right to terminate this license under this
Article 2.5.

         2.6 BD shall inform Accelr8 upon creation of an active material item
number for a BACcel Platform product, which enables commercial sales to
customers other than internal BD businesses or Affiliates. Should BD not create
an active material item number for a BACcel Platform product or no longer
maintain an active material item number for a BACcel Platform product, then
Accelr8 shall be entitled to terminate the ELA upon ninety (90) days written
notice unless BD cures within that ninety (90) day period.

         2.7 Within thirty (30) days of the ELA Effective Date, Accelr8 shall
initiate a transfer to BD of copies of all Accelr8 Background Know-How requested
by BD. BD may thereafter request additional items within Accelr8 Background
Know-How from time-to-time, and Accelr8 shall provide the requested items in a
reasonable manner. In addition, Accelr8 shall provide reasonable technical
assistance to BD in product development activities utilizing the Accelr8
Background Know-How. BD shall reimburse Accelr8 for reasonable documented
out-of-pocket expenses for providing such Accelr8 Background Know-How and
reasonable technical assistance. Use of the Accelr8 Background Know-How shall be
subject to the provisions of this ELA.

         2.8 No rights to Accelr8 under any BD Background IP or BD's interest in
Program IP are granted hereunder.

                               ARTICLE 3 - PAYMENTS
                               --------------------

         3.1 In consideration for the rights and licenses granted herein, BD or
its Affiliate shall make payments to Accelr8 as follows: On Commercial Sales, BD
or its Affiliate shall pay Accelr8 a running royalty in an amount equal to [***]
percent ([***]%) of Net Sales of Licensed Products.

         3.2 With respect to sublicenses, BD or its Affiliate shall pay an
amount equal to thirty percent (30%) of all payments, royalties and the fair
market value of all goods, services and other remuneration received by BD from
sublicensees in consideration for a sublicense under Accelr8 Background Patent
Rights. BD shall not, however, be required to pass on any monies received by BD
from a sublicensee as payment for research or trials. Where BD receives from a
sublicensee anything of value in lieu of cash payments in consideration for the
sublicense, the cash value of such consideration shall be determined by
negotiation in good faith between the Parties.

         3.3 BD or its Affiliate shall make the payments to Accelr8 after
deducting withholding taxes, levies and other governmental charges only if
required by applicable law. BD agrees that it shall use reasonable efforts to
minimize any such required withholding taxes, levies or other governmental
charges. Accelr8 shall cooperate with BD and take all reasonable steps necessary
to allow BD to lawfully reduce or avoid such withholding taxes, levies or other
governmental charges, such cooperation to include the timely completion and
filing of any relevant forms and/or other documents. BD agrees that it shall
take all reasonable steps necessary to assist Accelr8 in obtaining a refund for
any amounts withheld.

         3.4 No multiple royalties shall be payable because any Licensed
Product, its manufacture, use, lease or sale are or shall be covered by more
than one patent or more than one claim of a patent in the Accelr8 Background
Patent Rights.

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         3.5 In the event that BD or its Affiliate is obligated to pay a royalty
to one or more third parties for a Licensed Product and the aggregate total
royalty rate on such Licensed Product exceeds [***] percent ([***]%)in the
absence of any applicable royalty stacking adjustments, then the running royalty
under this ELA shall be reduced by an amount equal to: fifty percent (50%) of
the difference between the aggregate royalty rate and [***] percent ([***]%).
However, in no event shall the running royalty drop below [***] percent
([***]%). (For example, [***].)

         3.6 The payments by BD to Accelr8 hereunder, the provisions of Articles
2.4, 2.5 and 2.6 are considered to be complete satisfaction of any duty imposed
upon BD to commercially exploit the Accelr8 Background IP.

                        ARTICLE 4 - REPORTS AND RECORDS
                        -------------------------------

         4.1 After the first Commercial Sale of a Licensed Product, within sixty
(60) days after the last business day of each calendar quarter of each license
year of this ELA, BD shall submit to Accelr8 a written report with respect to
the preceding calendar quarter (the "Payment Report") stating: (a) the
quantities of Licensed Products sold by BD, and the monetary amount of all sales
and all deductions therefrom used to calculate Net Sales with respect to sales
of Licensed Products during the reporting period and the royalties due
therefrom, and (b) royalty-bearing sublicensing revenue and the sources thereof.

         4.6 Simultaneously with the submission of each Payment Report, BD shall
make payments to Accelr8 of the amounts due for the calendar quarter covered by
the Payment Report. Payment shall be by check payable to Accler8 and sent to the
address for Accelr8 set forth in Article 10, or to such other address as Accelr8
may specify by notice hereunder, or, if requested by Accelr8, by wire transfer
of immediately available funds to a bank and account identified by notice to BD
by Accelr8.

         4.7 Within sixty (60) days after the date of termination or expiration
of this ELA, BD shall pay Accelr8 any and all amounts that are due pursuant to
this ELA as of the date of such termination or expiration, together with a
Payment Report for such payment, except that such Payment Report shall cover the
period from the end of the last calendar quarter prior to termination or
expiration to the date of termination or expiration.

         4.8 With respect to revenues obtained by BD in foreign countries, BD
shall make royalty payments to Accelr8 in United States Dollars. Royalty
payments for transactions outside the United States shall first be determined in
the currency of the country in which they are earned, and then converted to
United States dollars using the buying rates of exchange quoted by Citibank,
N.A. (or its successor) in New York, New York for the last business day of the
calendar quarter in which the royalties were earned.

         4.9 BD shall maintain usual books of account and records showing Net
Sales of Licensed Products in sufficient detail to allow the royalties payable
by BD to be accurately determined. Upon reasonable notice, no more than once per
year, such books and records shall be open to inspection, during usual business
hours, by an independent certified public accountant (bound by an obligation of
confidentiality to BD) to whom BD has no reasonable objection, for two (2) years
after the calendar quarter to which they pertain, solely for purposes of
verifying the accuracy of the amounts paid by BD under this ELA. The cost of any
such inspection shall be borne by Accelr8. In the event that such review
reasonably shows that BD has underpaid royalties by more than five percent (5%),
with respect to any calendar quarter, BD shall pay, within thirty (30) days
after demand by Accelr8, the costs and expenses of such review, as well as all
unpaid royalties. If the inspection shows an overpayment, Accelr8 shall provide
BD with a credit against future royalties in an amount equal to such
overpayment. All information learned by Accelr8 in connection with any such
audit shall be treated by Accelr8 as BD's Confidential Information hereunder.

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                   ARTICLE 5 - PATENT MATTERS AND LITIGATION
                   -----------------------------------------

         5.1 Accelr8 shall diligently prepare, apply for, prosecute, obtain and
maintain ("Prosecute" or "Prosecution") Accelr8 Background Patent Rights using
counsel to which BD has no reasonable objection. BD shall be provided with
copies of all documents relating to the Prosecution of Accelr8 Background Patent
Rights that are within or relevant to the Field, in sufficient time to review
such documents and comment thereon, if desired by BD, prior to filing, provided
that, if BD has not commented on such documents prior to the deadline for filing
a response to the relevant government patent office, Accelr8 will be free to
respond without consideration of BD's comments. Accelr8 agrees to pay due
consideration to BD's comments and use reasonable efforts to implement BD's
reasonable requests consistent with its commercial goals and interests.
Prosecution costs shall be borne equally between the Parties, unless BD's
license grant is converted to a non-exclusive license under Article 2.4, in
which case Prosecution costs shall then be borne fully by Accelr8.

         5.2 If Accelr8 elects not to Prosecute any patents or patent
applications within Accelr8 Background Patent Rights relevant in the Field in
any country(ies) or region(s) in the world, Accelr8 shall promptly notify BD in
writing in sufficient time, but not less than sixty (60) days, for BD to take
action, and BD shall thereafter have the right, but not any obligation, to
Prosecute such patent rights in such country(ies) or region(s) at its own cost,
and in its own name ("Surrendered Patent"). If BD elects to take over the
Prosecution of any such Surrendered Patent, Accelr8 agrees to assign, and does
hereby assign, to BD all right, title and interest in and to such Surrendered
Patent.

         5.3 BD shall have responsibility for Prosecuting patents or
applications within Program IP, at its sole expense, using BD internal counsel
or using external counsel to which Accelr8 has no reasonable objection. Accelr8
shall be provided with copies of all documents relating to the Prosecution of
Program IP that are relevant outside the Field, in sufficient time to review
such documents and comment thereon. .BD agrees to pay due consideration to
Accelr8's comments and use reasonable efforts to implement Accelr8's reasonable
requests consistent with BD's commercial goals and interests. If Accelr8 has not
commented on such documents prior to the deadline for filing a response to the
relevant government patent office, BD will be free to respond without
consideration of Accelr8's comments.

         5.4 If a dispute arises with respect to Prosecution, Accelr8 and BD
shall first attempt to resolve the dispute through good faith discussions. If no
resolution is reached, to accommodate a relevant patent office deadline, either
Party may, at its sole expense, refer the dispute to an independent patent
attorney, to which the other Party has no reasonable objection, whose decision
shall be final and binding.

         5.5 In the event that either BD or Accelr8 become aware of any
potential infringement or misuse of Accelr8 Background IP or Program IP in the
Field by a third party ("Infringing Party"), such Party shall notify the other
Party in writing and provide a summary of the relevant facts and circumstances.

         5.6 Accelr8 shall not notify a third party of the potential
infringement of Accelr8 Background IP, (i) in the Field, without first obtaining
the consent of BD, or (ii) outside the Field, without providing advance written
notice to BD including a summary of the relevant non-confidential facts
supporting such potential infringement. Accelr8 hereby grants to BD all rights
to sue and recover damages or obtain injunctive relief for past and future
infringement, misappropriation, violation or breach of Accelr8 Background IP or
Program IP, in the Field. During the term of this Agreement, BD shall have the
first right, but no obligation, to assert, enforce and defend Accelr8 Background
IP or Program IP in the Field ("Litigate" or "Litigation") and its rights
pursuant to this Agreement, at its own expense, and to recover any damages,
awards or settlements resulting therefrom. Accelr8 hereby agrees that BD may
join it as a necessary party plaintiff in any such suit, without expense to
Accelr8. BD shall hold harmless and indemnify Accelr8 from and against any order

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for costs arising without fault or negligence of Accelr8 that may be made
against them by reason of being named a party plaintiff in such proceedings. BD
shall have sole control of any Litigation and all negotiations for its
settlement or compromise, and shall have the sole right, in accordance with the
terms and conditions herein, to sublicense solely in the Field any alleged
infringer under Accelr8 Background IP or Program IP. The total cost of any
Litigation commenced or defended solely by BD shall be borne by BD. All
recoveries from any such action shall be first applied to reimburse BD its cost
and expenses including, without limitation, attorney's fees and court costs. Any
excess amounts shall be deemed to be Net Sales. Notwithstanding the foregoing,
BD shall have no right to litigate or compromise issues with respect to the
rights retained by Accelr8 under this Agreement or which may adversely affect
Accelr8 Background IP without the prior written consent of Accelr8, not to be
unreasonably withheld, conditioned or delayed.

         5.7 If BD decides that it shall not bring suit against, or enter into
negotiations with, an Infringing Party as provided in Article 5.6, then BD shall
so notify Accelr8 and, in that event only, Accelr8 shall have the right, but
shall not be obligated, to Litigate the relevant action and to recover, for its
own account, any damages, awards or settlements resulting therefrom. BD hereby
agrees that Accelr8 may join BD as a necessary party plaintiff in any such suit,
without expense to BD. Accelr8 shall hold harmless and indemnify BD from and
against any order for costs arising without fault or negligence of BD that may
be made against BD by reason of being named a party plaintiff in such
proceedings. Accelr8 shall have sole control of any such suit and all
negotiations for its settlement or compromise, provided that Accelr8 shall not
settle or compromise any such suit or enter into any consent order for the
settlement or compromise thereof that adversely affects the licenses or rights
of BD hereunder without the prior written consent of BD, and provided further
that BD shall have the sole right in accordance with the terms and conditions
hereof to sublicense any alleged infringer under Accelr8 Background IP or
Program IP in the Field. The total cost of any such Litigation commenced or
defended solely by Accelr8 shall be borne by Accelr8.

         5.8 In the event that any action, suit or proceeding is brought
against, or written notice or threat thereof is provided to, BD alleging
infringement of any third party patent or unauthorized use or misappropriation
of any third party technology or know-how arising out of or in connection with
BD's manufacture, use, offer for sale, sale or importation of the Licensed
Products, BD shall have the right to defend at its own expense such action, suit
or proceeding and, in furtherance of such rights, Accelr8 hereby agrees that BD
may join it as a party in such suit, without expense to Accelr8. BD shall hold
harmless and indemnify Accelr8 from and against any order for costs and all
damages and settlements arising without fault of Accelr8 that may be made
against Accelr8 in such proceedings, unless such order arises out of or relates
to facts and circumstances involving a breach of any representation, warranty or
covenant by Accelr8.

         5.9 If a party undertakes Litigation and/or Prosecution of the Accelr8
Background IP or Program IP by legal or patent office proceedings pursuant to
this Agreement, the other party shall, at the request and expense of the party
undertaking such Litigation and/or Prosecution, cooperate in all reasonable
respects, and to the extent possible, have its employees testify when requested
and make available relevant records, papers, information, samples and the like.

                          ARTICLE 6 - REPRESENTATIONS
                          ---------------------------

         6.1 Accelr8 represents and warrants to BD that, to the best of
Accelr8's knowledge as of the Effective Date, (a) Accelr8 owns all right, title
and interest in and to Accelr8 Background IP; (b) Accelr8 Background Patent
Rights have been duly prepared, filed, prosecuted, obtained and maintained in
accordance with all applicable laws, rules and regulations; (c) Accelr8 is not
aware of any third party whose intellectual property rights would be infringed
or misappropriated by the practice of Accelr8 Background IP nor of any third
party who is infringing or misappropriating Accelr8 Background IP; (d) Accelr8
does not own or control any patents or patent applications other than Accelr8
Background Patent Rights that currently, or when issued, would be infringed by

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the making, using, offering for sale, selling or importing of any Licensed
Product; (e) no open source or public library software, including any version of
any software licensed pursuant to any GNU public license, is, in whole or in
part, embodied or incorporated into any software within Accelr8 Background IP,
and (f) Accelr8 has the lawful right to enter into the ELA and to grant the
licenses hereunder without the consent or approval of another person or entity.

         6.2 BD represents and warrants to Accelr8 that it has the lawful right
and authority to enter into this ELA without the consent or approval of another
person or entity. Accelr8 represents and warrants to BD that it has the lawful
right and authority to enter into this ELA without the consent or approval of
another person or entity.

                          ARTICLE 7 - INDEMNIFICATION
                          ---------------------------

         7.1 During the term of this ELA, BD shall indemnify, hold harmless and
defend Accelr8, and its officers, employees and agents (the "Indemnitees")
against any and all claims (including but not limited to claims of products
liability), suits, losses, damage, costs, fees, and expenses (including but not
limited to reasonable attorneys' fees and other legal costs) resulting from or
arising out of BD's exercise of the license granted to it hereunder. However, BD
need not indemnify Indemnitees to the extent that a claim, suit, loss, damage,
cost, fee or expense arises out of the gross negligence or intentional
misconduct of an Indemnitee.

               7.1.1 BD shall have the exclusive right to control the defense of
any such action, including the right to select counsel to defend any Indemnitee,
and to settle any claim.

               7.1.2 The obligations of BD stated in Article 7 shall apply only
if the relevant Indemnitee notifies BD in writing within fifteen (15) days
following receipt of written notice of any claim or suit brought against
Indemnitee in respect of which Indemnitee intends to invoke the provisions of
this Article 7. BD shall keep the Indemnitee informed on a current basis of its
defense of any claims pursuant to this Article 7.

         7.2 IN NO EVENT WILL EITHER PARTY BE LIABLE FOR ANY INCIDENTAL, SPECIAL
OR CONSEQUENTIAL DAMAGES (INCLUDING BUT NOT LIMITED TO LOST PROFITS OR BUSINESS
OPPORTUNITIES) IN CONNECTION WITH THE ELA OR RESULTING FROM EXERCISE OF THIS
LICENSE OR THE USE OF LICENSED PRODUCTS, EVEN IF A PARTY HAS BEEN ADVISED OF THE
POSSIBILITY OF SUCH DAMAGE AND NOTWITHSTANDING ANY FAILURE OF ESSENTIAL PURPOSE
OF ANY REMEDY SET FORTH IN THIS AGREEMENT.

         7.3 ACCELR8'S TOTAL LIABILITY ARISING UNDER OR IN CONNECTION WITH THIS
AGREEMENT, REGARDLESS OF THE FORM OF ACTION, SHALL BE LIMITED TO THE TOTAL
PAYMENTS RECEIVED FROM BD UNDER THIS ELA AND UNDER THE AGREEMENT.

                             ARTICLE 8 - ASSIGNMENT
                            -----------------------

         8.1 This ELA is not assignable and any attempt to do so shall be void,
without the express written approval of the other Party, which shall not be
unreasonably withheld. The provisions of the ELA shall be binding upon and inure
to the benefit of the Parties and the respective successors and assigns of each
of the Parties.

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                            ARTICLE 9 - TERMINATION
                            -----------------------

         9.1 Unless otherwise terminated by operation of law or by acts of the
Parties in accordance with the terms of this ELA, this ELA shall terminate upon
expiration of the last to expire patent within Accelr8 Background Patent Rights.

         9.2 This ELA, in whole or in part, shall be terminable by BD at any
time, and for any or no reason, upon sixty (60) days written notice to Accelr8.
Upon such termination by BD, the Non-Exclusive License Agreement shall come into
force and effect.

         9.3 This ELA shall be terminable upon the material breach or default of
either Party. In the event of a material breach or default by a Party
("Defaulting Party"), the other Party ("non-Defaulting Party") shall give the
Defaulting Party written notice of the default and its election to terminate
this ELA effective at the expiration of a period of sixty (60) days from the
date of the notice. If the Defaulting Party fails to resolve the default in the
probation period by (i) curing the default, (ii) providing a written explanation
satisfactory to the Non-Defaulting Party that a default has not occurred, or
(iii) entering into a written agreement with the Non-Defaulting Party for the
cure or other resolution of the default, then this ELA shall terminate upon the
expiration of such sixty (60) day period. All termination rights shall be in
addition to and not in substitution for any other remedies that may be available
to the Non-Defaulting Party. Termination pursuant to this Article shall not
relieve the Defaulting Party from liability and damages to the Non-Defaulting
Party for default. Failure to meet the expenditure milestones under Article 2.4
shall not be considered a material breach hereunder.

         9.4 If this ELA is terminated by Accelr8 due to BD's material breach,
or pursuant to Article 2.5 or 2.6, the Non-Exclusive License Agreement shall
come into force and effect.

         9.5 Any termination of this ELA for any reason does not relieve either
Party of any obligation or liability accrued prior to the termination or rescind
anything done by either Party and the termination does not affect in any manner
any rights of either Party arising under this ELA prior to the termination,
including, but not limited to, the right of Accelr8 to receive royalties under
Article 4.2.

         9.6 To the extent permitted by law, if any Party hereto ("Bankrupt
Party") shall become insolvent, or shall suspend business or shall file a
voluntary petition or answer admitting the jurisdiction of the Court or the
material allegations of a petition, or shall consent to an involuntary petition
pursuant to or purporting to be pursuant to any reorganization or insolvency law
of any jurisdiction, or shall make an assignment for the benefit of creditors,
or shall apply for or consent to the appointment of a receiver or trustee of a
substantial part of its property ("Bankruptcy Event"), then it is the Parties'
intent that this ELA and the rights and licenses granted to BD hereunder by the
Bankrupt Party must be adopted by any bankruptcy trustee or relevant third Party
charged with the disposition of same, and cannot be rejected. The Parties
acknowledge that this ELA contemplates the manner in which the Parties may
retain the rights granted to them hereunder by the Bankrupt Party, if they
choose to do so in accordance with Section 365(n) of the Bankruptcy Code. It is
the Parties' intent that, upon the occurrence of any Bankruptcy Event, BD shall
be entitled to retain the rights granted to them hereunder by the Bankrupt Party
in all items delivered or required to be delivered under this ELA.

         9.7 The terms and conditions of the following provisions shall survive
termination or expiration of this ELA for as long as necessary to permit their
full discharge: Articles 4.5 (REPORTS AND RECORDS), 5.5 and 5.6 (PATENT MATTERS
AND LITIGATION), 6 (REPRESENTATIONS), 7 (INDEMNIFICATION), 11 (CONFIDENTIALITY)
and 12 (MISCELLANEOUS). Upon a lawful termination by Accelr8 under Article 9.3
or by BD under Article 9.2 hereof, BD shall have no further rights to the
Licensed Products, except that BD may sell or otherwise dispose of all Licensed

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Products that have been manufactured prior to the effective date of such
termination, or are in the process of being manufactured on such date, and shall
make payments to Accelr8 required under Article 3.2, and Accelr8 shall have no
further right to payment of any other license fees.

         9.8 Notwithstanding Article 9.3 herein, if BD terminates this ELA for
material breach or default of Accelr8, BD's rights and licenses hereunder shall
continue, but any and all obligations of BD shall terminate.

            ARTICLE 10 - PAYMENTS, NOTICES AND OTHER COMMUNICATIONS
             -------------------------------------------------------

         Any payment, notice or other communication pursuant to this ELA shall
be sufficiently made or given on the date of mailing if sent to such Party by
certified first class mail, postage prepaid or in the case of a notice or
communication faxed with return receipt confirmation of complete delivery and
followed up by a written copy delivered by first class mail, addressed to it at
its address below or as it shall designate by written notice given to the other
Party:

         In the case of Accelr8:
              7000 North Broadway
              Bldg. 3-307
              Denver, Colorado 80221
              Fax:  303-863-1218
              Attention: Thomas V. Geimer, Chairman and CEO

         In the case of BD:

              For BD:
              Becton, Dickinson and Company
              7 Loveton Circle
              Sparks, Maryland 21152
              Fax: 410-316-4081
              Attention: Director / Strategic Planning and Business Development

              with a copy to :
              Becton, Dickinson and Company
              1 Becton Drive  MC089
              Franklin Lakes, NJ  07417
              Fax:  (201) 848-9228
              Attention:  Vice President, Chief Intellectual Property Counsel

                          ARTICLE 11 - CONFIDENTIALITY
                          -----------------------------

         11.1 With regard to Confidential Information, the receiving Party
agrees:

               11.1.1 not to use the Confidential Information except for the
purposes of this ELA ;

               11.1.2 to safeguard Confidential Information against disclosure
to others with the same degree of care as it exercises with its own Confidential
Information of a similar nature, but in no event less than a reasonable degree
of care;

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               11.1.3 not to disclose Confidential Information to others (except
to its employees, agents or consultants who are bound by a like obligation of
confidentiality) without the express prior written permission of the disclosing
Party,

               11.1.4 except that the receiving Party shall not be prevented
from using or disclosing any of the Confidential Information:

                    (a) which the receiving Party can demonstrate by
pre-existing, competent written records was previously known to it; or

                    (b) which is now, or becomes in the future, public knowledge
other than through acts or omissions of the receiving Party; or

                    (c) which is lawfully obtained by the receiving Party from
sources independent of the disclosing Party; and

                    (d) which are required by law to be disclosed, only to the
extent so required.

         11.2 The secrecy obligations of the Parties with respect to
Confidential Information shall continue for a period ending five (5) years from
the termination date of this ELA.

         11.3 Notwithstanding Article 11.1, the Parties shall have the right to
disclose Confidential Information (i) as necessary in the course of seeking or
enforcing patent rights, or obtaining regulatory approval to manufacture or
market Licensed Products, and (ii) as reasonably required in the course of any
actual or potential financing, business or sublicensing arrangement; provided,
however, that any disclosure under (ii) shall be pursuant to a confidentiality
agreement between the respective Party and such third party which preserves the
rights of the Parties hereunder.

                      ARTICLE 12 - MISCELLANEOUS PROVISIONS
                     --------------------------------------

         12.1 Upon request, BD will consider in good faith its ability to
manufacture BACcel Platform products for Accelr8's sale or distribution, for
applications outside the Field.

         12.2 This ELA shall be construed, governed, interpreted and applied in
accordance with the laws of the State of New Jersey, without reference to choice
or law doctrine, except that questions affecting the construction and effect of
any patent shall be determined by the law of the country in which the patent was
granted. Any controversy arising hereunder, except as otherwise explicitly
stated, shall be subject to the exclusive jurisdiction of the courts located in
New Jersey and each Party hereby submits itself for the sole purpose of this ELA
and any controversy arising hereunder to the jurisdiction of the courts located
in the District of New Jersey and any courts of appeal therefrom, and waives any
objection on the grounds of lack of jurisdiction (forum non conveniens or
otherwise) to the exercise of such jurisdiction over it by any such courts.

         12.3 The Parties acknowledge that this ELA sets forth the entire
agreement and understanding of the Parties as to the subject matter hereof, and
shall not be subject to any change or modification except by the execution of a
written instrument subscribed to by the Parties hereto.

         12.4 The provisions of this ELA are severable, and in the event that
any provisions of this ELA shall be determined to be invalid or unenforceable
under any controlling body of the law, such invalidity or unenforceability shall
not in any way affect the validity or enforceability of the remaining provisions
hereof.

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         12.5 The failure of either Party to assert a right hereunder or to
insist upon compliance with any term or condition of this ELA shall not
constitute a waiver of that right or excuse a similar subsequent failure to
perform any such term or condition by the other Party. No waiver of any term or
condition of this ELA shall be effective unless in writing and signed by the
Party granting such waiver.

         12.6 Neither BD nor Accelr8 shall be responsible for and the terms of
this ELA shall be inapplicable to any default or delays which are due to cause
beyond such Party's control, including but without limitation acts of God or of
the public enemy, acts or any order of a government, fires, floods, or other
natural disasters, embargoes, accidents, explosions, strikes, or other labor
disturbances (regardless of the reasonableness of the demands of labor),
shortages of fuel, power or raw materials, inability to obtain or delays of
transportation facilities, incidents of war, or other events causing the
inability of a Party acting in good faith with due diligence, to perform its
obligations under this ELA.

         12.7 Neither Party shall use the name of the other Party or any
adaptation thereof in any publication, advertising, promotion, sales literature
or packaging without the prior written consent of the other Party. Any press
release, public announcement or Any press release, public announcement or
similar publicity by the Parties with respect to this ELA shall be subject to
the prior consent of the other Party, which consent shall not be unreasonably
withheld, unless such communication is required to be made by law or pursuant to
the rules and regulations of the Securities and Exchange Commission or the New
York Stock Exchange listing requirements or an equivalent agency and after
consultation and coordination between the Parties. Such press release, public
announcement or similar publicity shall be limited to the existence of the ELA
and shall not disclose the terms thereof. In the case of required communication
to agencies such as listed above, the terms of the ELA shall be redacted unless
prohibited by applicable laws or rules.

         12.8 Nothing herein contained shall be construed to place the Parties
in the relationship of partners or joint venturers or principal and agent or
create any entity or association, and neither Party shall have the power to
obligate or bind the other in any manner whatsoever.

         IN WITNESS WHEREOF, the persons executing this Agreement in duplicate
originals, on behalf of the Parties hereto, represent and warrant, that they are
duly authorized officers and representatives and have authority to execute such
Agreement on behalf on their respective Party.

ACCELR8 TECHNOLOGY CORPORATION            BECTON, DICKINSON AND COMPANY

By:  ________________________             By: __________________________________
         Thomas V. Geimer                           Philippe Jacon
         Chairman and CEO                  President - Microbiology Systems
                                                      BD Diagnostics

Date:                                     Date:

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CERTAIN PORTIONS OF THIS EXHIBIT HAVE BEEN OMITTED PURSUANT TO RULE 24B-2 AND
ARE SUBJECT TO A CONFIDENTIAL TREATMENT REQUEST. COPIES OF THIS EXHIBIT
CONTAINING THE OMITTED INFORMATION HAVE BEEN FILED SEPARATELY WITH THE
SECURITIES AND EXCHANGE COMMISSION. THE OMITTED PORTIONS OF THIS DOCUMENT ARE
MARKED WITH A [***].

                                   Appendix C
                                   ----------

                         NON-EXCLUSIVE LICENSE AGREEMENT
                         -------------------------------

         This Non-Exclusive License Agreement ("NELA") is made and entered into
effective pursuant to Article 6 of the Agreement or Article 9 of the Exclusive
License Agreement ("NELA Effective Date"), by and between Accelr8 Technology
Corporation, having a place of business at 7000 North Broadway, Building 3-307,
Denver, Colorado 80221, ("Accelr8") and Becton, Dickinson and Company, a
corporation duly organized under the laws of the State of New Jersey and having
its principal office in 1 Becton Drive Franklin Lakes, NJ 07417 for itself and
its Affiliates ("BD"), (each a "Party" and collectively the "Parties").

                                   WITNESSETH

         WHEREAS, the Parties entered into a Research and Option Agreement
("Agreement") effective May 16, 2008 to which this NELA is attached;

         WHEREAS, Article 6 of the Agreement provided BD with the Option for an
exclusive license to certain Accelr8 intellectual property; and

         WHEREAS, the Parties agreed that if BD chose not to exercise the
Option, or if BD exercised the Option but such exclusive license was
subsequently terminated, this NELA would come into force and effect;

         NOW, THEREFORE, in consideration of the premises and the mutual
covenants contained herein, the Parties hereto agree as follows:

                            ARTICLE 1 - DEFINITIONS
                            -----------------------

         Capitalized terms not defined herein shall have the meaning set forth
in the Agreement. For the purposes of this NELA, the following words and phrases
shall have the following meanings:

         1.1 "BD Background Licensed Product" shall mean collectively any
process or product used in or directed to use in Field, (i) that uses BD
Background IP or (ii) that is covered by a Valid Claim of an issued patent
within BD Background IP.

         1.2 "Commercial Sales" shall mean any sale of a Licensed Product in any
country in the world, excluding sales for purposes of testing, validation
studies, marketing evaluations or clinical trials, or provided as marketing
samples.

         1.3 "Kit" shall mean a combination product offered or sold by Accelr8
that includes a Licensed Product in combination with identifiable products
having a separate use or purpose not licensed hereunder.

         1.4 "Licensed Product" shall mean BD Background Licensed Product and/or
Program IP Licensed Product, as the context indicates.

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         1.5 "Net Sales" shall mean the sum of all amounts invoiced by Accelr8
for the sale, lease, rental or other mode of transfer, whether permanent or
temporary, of Licensed Product to third parties, less, to the extent not already
reflected in the invoiced amount:

               1.5.1 reasonable cash discounts to purchasers allowed and taken;

               15.2 amounts for transportation or shipping charges from the
place of manufacture to the customer's location actually paid by Accelr8;

               1.5.3 taxes and duties imposed on the sale of Licensed Product,
levied and actually paid;

               1.5.4 refunds, rebates, or allowances;

               1.5.5 transfers for non-commercial testing, validation studies,
marketing evaluations and clinical trials; and/or

               1.5.6 free distribution (not in exchange for services or
payments) of Licensed Product used solely as marketing samples to develop or
promote the Licensed Product.

         In the case of sale or other transfer of the Licensed Product as part
         of a Kit, the Net Sales shall be determined as follows: If the Licensed
         Product is also sold separately from the Kit, the Net Sales on which
         the royalty rate is applied shall be an amount equal to the Net Sales
         of the Licensed Product if sold separately in a similar transaction
         involving similar volumes of Licensed Product at about the same time as
         the transaction involving such Kit.

         If the Licensed Product or the identifiable products are not sold
         separately from the Kit, the applicable Net Sales for royalty purposes
         shall be determined by multiplying the Net Sales of the Kit by the
         fraction A/(A+B) where A equals the standard fully absorbed cost to BD
         of the Licensed Product and B equals the fully absorbed cost to BD of
         the remaining products in the Kit, such costs determined by using BD
         standard accounting principles in accordance with generally accepted
         accounting practice.

         In the case where an instrument is placed pursuant to a reagent rental
         agreement or an analogous agreement in which a purchaser is provided an
         instrument for use in conjunction with Licensed Products, including but
         not limited to or a service contract in conjunction with the
         instrument, and the costs associated with the placement and use of the
         instrument are not separately billed but instead represent some portion
         of the purchase price of the Licensed Products, then BD shall be
         entitled to reduce the Net Sales of such Licensed Products to allow for
         deduction of instrument-related charges such as interest for the
         financing of the instrument supplied, training, warranty and
         post-warranty cost of instrument service, using BD standard accounting
         principles in accordance with generally accepted accounting practice.

         The term Net Sales in the case of non-cash sales, shall mean the fair
         market value of all equivalent or other consideration received by
         Accelr8. If such fair market value of the non-cash consideration is not
         readily and undisputably ascertainable, the Parties shall discuss in
         good faith the cash value of such non-cash consideration, and payment
         to BD shall be based on such cash value.

         1.6 "Program IP Licensed Product" shall mean collectively any process
or product used in or directed to use in Field, (i) that uses Program IP or (ii)
that is covered by a Valid Claim of an issued patent within Program IP.

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         1.7 "Valid Claim" shall mean an issued claim of an unexpired patent
which shall not have been withdrawn, canceled or disclaimed or held invalid or
unenforceable in an unappealed or unappealable decision.

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                    ARTICLE 2 - INTELLECTUAL PROPERTY RIGHTS
                   ----------------------------------------

         2.1 Program IP shall be jointly owned by BD and Accelr8, and either
Party may use the Program IP for any purpose, subject to any obligations set
forth in this NELA.

         2.2 BD shall grant Accelr8 a limited, non-exclusive, royalty-bearing
license, with no right to sublicense, to BD Background IP which (i) was
developed during the term of the Agreement, (ii) was developed as part of BD's
assessment of the BACcel Platform technology, and (iii) is necessary for Accelr8
to make, sell, use or have made a BACcel Platform product.

         2.3 Except as explicitly set forth herein, no rights under any other
intellectual property of the Parties are granted hereunder.

                              ARTICLE 3 - PAYMENTS
                              --------------------

         3.1 In consideration for the rights granted herein, and the rights and
payments provided in the Agreement, Accelr8 shall make payments to BD as
follows:

               3.1.1 On Commercial Sales, Accelr8 shall pay BD a running royalty
in an amount equal to [***] percent ([***]%)of Net Sales of Program IP Licensed
Products, up to the total amount paid by BD to Accelr8 under Article 2D of the
Research and Option Agreement, not to exceed a maximum of [***] dollars
($[***]).

               3.2.2 On Commercial Sales, Accelr8 shall pay BD a running royalty
in an amount equal to [***] percent ([***]%) of Net Sales of BD Background
Licensed Products, with no maximum.

         3.2 With respect to sublicenses of Program IP, Accelr8 shall pay an
amount equal to thirty percent (30%) of all payments, royalties and the fair
market value of all goods, services and other remuneration received by Accelr8
from sublicensees in consideration for a sublicense directed to Program IP
Licensed Products in whole or in part. Accelr8 shall not, however, be required
to pass on any monies received by Accelr8 from a sublicencee as payment for
research or trials. Where Accelr8 receives from a sublicensee anything of value
in lieu of cash payments in consideration for the sublicense, the cash value of
such consideration shall be determined by negotiation in good faith between the
Parties.

         3.3 Accelr8 shall make the payments to BD after deducting withholding
taxes, levies and other governmental charges only if required by applicable law.
Accelr8 agrees that it shall use reasonable efforts to minimize any such
required withholding taxes, levies or other governmental charges. BD shall
cooperate with Accelr8 and take all reasonable steps necessary to allow Accelr8
to lawfully reduce or avoid such withholding taxes, levies or other governmental
charges, such cooperation to include the timely completion and filing of any
relevant forms and/or other documents. Accelr8 agrees that it shall take all
reasonable steps necessary to assist BD in obtaining a refund for any amounts
withheld.

         3.4 No multiple royalties shall be payable because any Licensed
Product, its manufacture, use, lease or sale are or shall be covered by more
than one patent or more than one claim of a patent.

                        ARTICLE 4 - REPORTS AND RECORDS
                        -------------------------------

         4.1 After the first Commercial Sale of a Licensed Product, within sixty
(60) days after the last business day of each calendar quarter of each license
year of this NELA, Accelr8 shall submit to BD a written report with respect to
the preceding calendar quarter (the "Payment Report") stating: a) the quantities
of Licensed Products sold by Accelr8, and the monetary amount of all sales and
all deductions therefrom used to calculate Net Sales with respect to sales of
Licensed Products during the reporting period and the royalties due therefrom,
and (b) royalty-bearing sublicensing revenue and the sources thereof.

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         4.2 Simultaneously with the submission of each Payment Report, Accelr8
shall make payments to BD of the amounts due for the calendar quarter covered by
the Payment Report. Payment shall be by check payable to BD and sent to the
address for BD set forth in Article 10, or to such other address as BD may
specify by notice hereunder, or, if requested by BD, by wire transfer of
immediately available funds to a bank and account identified by notice to
Accelr8 by BD.

         4.3 Within sixty (60) days after the date of termination or expiration
of this NELA, Accelr8 shall pay BD any and all amounts that are due pursuant to
this NELA as of the date of such termination or expiration, together with a
Payment Report for such payment, except that such Payment Report shall cover the
period from the end of the last calendar quarter prior to termination or
expiration to the date of termination or expiration.

         4.4 With respect to revenues obtained by Accelr8 in foreign countries,
Accelr8 shall make royalty payments to BD in United States Dollars. Royalty
payments for transactions outside the United States shall first be determined in
the currency of the country in which they are earned, and then converted to
United States dollars using the buying rates of exchange quoted by Citibank,
N.A. (or its successor) in New York, New York for the last business day of the
calendar quarter in which the royalties were earned.

         4.5 Accelr8 shall maintain usual books of account and records showing
Net Sales of Licensed Products in sufficient detail to allow the royalties
payable by Accelr8 to be accurately determined. Upon reasonable notice, no more
than once per year, such books and records shall be open to inspection, during
usual business hours, by an independent certified public accountant (bound by an
obligation of confidentiality to Accelr8) to whom Accelr8 has no reasonable
objection, for two (2) years after the calendar quarter to which they pertain,
solely for purposes of verifying the accuracy of the amounts paid by Accelr8
under this NELA. The cost of any such inspection shall be borne by BD. In the
event that such review reasonably shows that Accelr8 has underpaid royalties by
more than five percent (5%), with respect to any calendar quarter, Accelr8 shall
pay, within thirty (30) days after demand by BD, the costs and expenses of such
review. If the inspection shows an overpayment, BD shall provide Accelr8 with a
credit against future royalties in an amount equal to such overpayment. All
information learned by BD in connection with any such audit shall be treated by
BD as Accelr8's Confidential Information hereunder.

                        ARTICLE 5 - PATENT MAINTENANCE
                        ------------------------------

         5.1 During the term of this Agreement, BD and Accelr8 shall jointly
prepare, apply for, prosecute, obtain and maintain ("Prosecute") patents and
applications for Program IP, using counsel to be chosen by mutual agreement.
Either party may, upon good cause, dismiss such counsel, whereupon the parties
shall mutually agree upon the selection of other counsel. Costs for Prosecution
of Program IP shall be shared equally by the Parties.

         5.2 If one Party ("First Party") no longer wishes to support
Prosecution of a particular patent or application, it shall notify the other
Party ("Second Party") in writing. The Second Party shall have the right to take
over Prosecution thereof, in which case the First Party agrees to assign, and
does hereby assign, all right, title and interest in and to such patent or
application to the Second Party.

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         5.3 If a dispute arises with respect to Prosecution, BD and Accelr8
shall first attempt to resolve the dispute through good faith discussions. If no
resolution is reached, to accommodate a relevant patent office deadline, either
party may, at its sole expense, refer the dispute to a patent attorney, to which
the other party has no reasonable objection, whose decision they shall agree to
and adopt.

         5.4 In the event that either Accelr8 or BD become aware of any
potential infringement or misuse of Program IP, such Party shall notify the
other Party of the potential infringement or misuse in writing and provide a
summary of the relevant facts and circumstances. The Parties shall discuss
appropriate action with respect to such potential infringement or misuse.

                          ARTICLE 6 - REPRESENTATIONS
                          ----------------------------

         6.1 Accelr8 represents and warrants to BD that it has the lawful right
and authority to enter into this NELA without the consent or approval of another
person or entity. BD represents and warrants to Accelr8 that it has the lawful
right and authority to enter into this NELA without the consent or approval of
another person or entity.

                           ARTICLE 7 - INDEMNIFICATION
                           ---------------------------

         7,1 During the term of this NELA, each Party (the "Indemnitor") shall
indemnify, hold harmless and defend the other Party, and its officers, employees
and agents (the "Indemnitees") against any and all claims, suits, losses,
damage, costs, fees, and expenses resulting from or arising out of the
Indemnitor's exercise of the license granted to it hereunder. However, the
Indemnitor need not indemnify Indemnitees to the extent that a claim, suit,
loss, damage, cost, fee or expense arises out of the gross negligence or
intentional misconduct of an Indemnitee

               7.1.1 The Indemnitor shall have the exclusive right to control
the defense of any such action, including the right to select counsel to defend
any Indemnitee, and to settle any claim.

               7.1.2 The obligations of the Indemnitor stated in Article 7 shall
apply only if the relevant Indemnitee notifies the Indemnitor in writing within
fifteen (15) days following receipt of written notice of any claim or suit
brought against Indemnitee in respect of which Indemnitee intends to invoke the
provisions of this Article 7. The Indemnitor shall keep the Indemnitee informed
on a current basis of its defense of any claims pursuant to this Article 7.

         7.2 IN NO EVENT WILL EITHER PARTY BE LIABLE FOR ANY INCIDENTAL, SPECIAL
OR CONSEQUENTIAL DAMAGES RESULTING FROM EXERCISE OF THIS LICENSE OR THE USE OF
LICENSED PRODUCTS.

                             ARTICLE 8 - ASSIGNMENT
                             ----------------------

         8.1 This NELA is not assignable and any attempt to do so shall be void,
without the express written approval of the other Party, which shall not be
unreasonably withheld, except in the case of the sale or transfer by a Party of
substantially the entire business to which the NELA pertains, in which case no
approval is needed. The rights and obligations of this NELA shall be binding
upon and inure to the benefit of the Parties and the respective successors and
assigns.

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                            ARTICLE 9 - TERMINATION
                            -----------------------

         9.1 Unless otherwise terminated by operation of law or by acts of the
Parties in accordance with the terms of this NELA, this NELA shall terminate
upon the later of: twenty (20) years from the NELA Effective Date or expiration
of the last to expire patent within Program IP.

         9.2 This NELA shall be terminable upon the material breach or default
of either Party. In the event of a material breach or default by a Party
("Defaulting Party"), the other Party ("non-Defaulting Party") shall give the
Defaulting Party written notice of the default and its election to terminate
this NELA effective at the expiration of a period of sixty (60) days from the
date of the notice. If the Defaulting Party fails to resolve the default in the
probation period by (i) curing the default, (ii) providing a written explanation
satisfactory to the Non-Defaulting Party that a default has not occurred, or
(iii) entering into a written agreement with the Non-Defaulting Party for the
cure or other resolution of the default, then this NELA shall terminate upon the
expiration of such sixty (60) day period. All termination rights shall be in
addition to and not in substitution for any other remedies that may be available
to the Non-Defaulting Party. Termination pursuant to this Article shall not
relieve the Defaulting Party from liability and damages to the Non-Defaulting
Party for default.

         9.3 Any termination of this NELA for any reason does not relieve either
Party of any obligation or liability accrued prior to the termination or rescind
anything done by either Party and the termination does not affect in any manner
any rights of either Party arising under this NELA prior to the termination,
including, but not limited to, the right of BD to receive royalties under
Article 4.2.

         9.4 The terms and conditions of the following provisions shall survive
termination or expiration of this NELA for as long as necessary to permit their
full discharge: Articles 4.5 (REPORTS AND RECORDS), 6 (REPRESENTATIONS), 7
(INDEMNIFICATION), 11 (CONFIDENTIALITY) and 12 (MISCELLANEOUS).

             ARTICLE 10 - PAYMENTS, NOTICES AND OTHER COMMUNICATIONS
             -------------------------------------------------------

         Any payment, notice or other communication pursuant to this NELA shall
be sufficiently made or given on the date of mailing if sent to such Party by
certified first class mail, postage prepaid or in the case of a notice or
communication faxed with return receipt confirmation of complete delivery and
followed up by a written copy delivered by first class mail, addressed to it at
its address below or as it shall designate by written notice given to the other
Party:

         In the case of Accelr8:
              7000 North Broadway
              Bldg. 3-307
              Denver, Colorado 80221
              Fax:  303-863-1218
              Attention: Thomas V. Geimer, Chairman and CEO

         In the case of BD:

              Becton, Dickinson and Company
              7 Loveton Circle
              Sparks, Maryland 21152
              Fax: 410-316-4081
              Attention: Director / Strategic Planning and Business Development

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                                  Confidential

              with a copy to :
              Becton, Dickinson and Company
              1 Becton Drive  MC089
              Franklin Lakes, NJ  07417
              Fax:  (201) 848-9228
              Attention:  Vice President, Chief Intellectual Property Counsel

                          ARTICLE 11 - CONFIDENTIALITY
                          ----------------------------

         11.1 With regard to Confidential Information, the receiving Party
agrees:

               11.1.1 not to use the Confidential Information except for
purposes of this NELA ;

               11.1.2 to safeguard Confidential Information against disclosure
to others with the same degree of care as it exercises with its own Confidential
Information of a similar nature, but in no event less than a reasonable degree
of care;

               11.1.3 not to disclose Confidential Information to others (except
to its employees, agents or consultants who are bound by a like obligation of
confidentiality) without the express prior written permission of the disclosing
Party,

               11..4 except that the receiving Party shall not be prevented from
using or disclosing any of the Confidential Information:

                    (a) which the receiving Party can demonstrate by
pre-existing, competent written records was previously known to it; or

                    (b) which is now, or becomes in the future, public knowledge
other than through acts or omissions of the receiving Party; or

                    (c) which is lawfully obtained by the receiving Party from
sources independent of the disclosing Party; and

                    (d) which are required by law to be disclosed, only to the
extent so required.

         11.2 The secrecy obligations of the Parties with respect to
Confidential Information shall continue for a period ending five (5) years from
the termination date of this NELA.

         11.3 Notwithstanding Article 11.1, the Parties shall have the right to
disclose Confidential Information (i) as necessary in the course of seeking or
enforcing patent rights, or obtaining regulatory approval to manufacture or
market Licensed Products, and (ii) as reasonably required in the course of any
actual or potential financing, business or sublicensing arrangement; provided,
however, that any disclosure under (ii) shall be pursuant to a confidentiality
agreement between the respective Party and such Third Party which preserves the
rights of the Parties hereunder.

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                                  Confidential

                     ARTICLE 12 - MISCELLANEOUS PROVISIONS
                     -------------------------------------

         12.1 This NELA shall be construed, governed, interpreted and applied in
accordance with the laws of the State of New Jersey, without reference to choice
or law doctrine, except that questions affecting the construction and effect of
any patent shall be determined by the law of the country in which the patent was
granted. Any controversy arising hereunder, except as otherwise explicitly
stated, shall be subject to the exclusive jurisdiction of the courts located in
New Jersey and each Party hereby submits itself for the sole purpose of this
NELA and any controversy arising hereunder to the jurisdiction of the courts
located in the District of New Jersey and any courts of appeal therefrom, and
waives any objection on the grounds of lack of jurisdiction (forum non
conveniens or otherwise) to the exercise of such jurisdiction over it by any
such courts.

         12.2 The Parties acknowledge that this NELA sets forth the entire
agreement and understanding of the Parties as to the subject matter hereof, and
shall not be subject to any change or modification except by the execution of a
written instrument subscribed to by the Parties hereto.

         12.3 The provisions of this NELA are severable, and in the event that
any provisions of this NELA shall be determined to be invalid or unenforceable
under any controlling body of the law, such invalidity or unenforceability shall
not in any way affect the validity or enforceability of the remaining provisions
hereof.

         12.4 The failure of either Party to assert a right hereunder or to
insist upon compliance with any term or condition of this NELA shall not
constitute a waiver of that right or excuse a similar subsequent failure to
perform any such term or condition by the other Party. No waiver of any term or
condition of this NELA shall be effective unless in writing and signed by the
Party granting such waiver.

         12.5 Neither Accelr8 nor BD shall be responsible for and the terms of
this NELA shall be inapplicable to any default or delays which are due to cause
beyond such Party's control, including but without limitation acts of God or of
the public enemy, acts or any order of a government, fires, floods, or other
natural disasters, embargoes, accidents, explosions, strikes, or other labor
disturbances (regardless of the reasonableness of the demands of labor),
shortages of fuel, power or raw materials, inability to obtain or delays of
transportation facilities, incidents of war, or other events causing the
inability of a Party acting in good faith with due diligence, to perform its
obligations under this NELA. 12.6 Neither Party shall use the name of the other
Party or any adaptation thereof in any publication, advertising, promotion,
sales literature or packaging without the prior written consent of the other
Party. Any press release, public announcement or Any press release, public
announcement or similar publicity by the Parties with respect to this NELA shall
be subject to the prior consent of the other Party, which consent shall not be
unreasonably withheld, unless such communication is required to be made by law
or pursuant to the rules and regulations of the Securities and Exchange
Commission or the New York Stock Exchange listing requirements or an equivalent
agency and after consultation and coordination between the Parties. Such press
release, public announcement or similar publicity shall be limited to the
existence of the NELA and shall not disclose the terms thereof. In the case of
required communication to agencies such as listed above, the terms of the NELA
shall be redacted unless prohibited by applicable laws or rules.

         12.7 Nothing herein contained shall be construed to place the Parties
in the relationship of partners or joint venturers or principal and agent or
create any entity or association, and neither Party shall have the power to
obligate or bind the other in any manner whatsoever.

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         IN WITNESS WHEREOF, the persons executing this Agreement in duplicate
originals, on behalf of the Parties hereto, represent and warrant, that they are
duly authorized officers and representatives and have authority to execute such
Agreement on behalf on their respective Party.

ACCELR8 TECHNOLOGY CORPORATION            BECTON, DICKINSON AND COMPANY

By:  ________________________             By: __________________________________
         Thomas V. Geimer                           Philippe Jacon
          Chairman and CEO                  President - Microbiology Systems
                                                     BD Diagnostics

Date:                                     Date:

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                                   Appendix D

                             [***][4 pages in total]

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