Document:

Synageva BioPharma Corp. 2005 Stock Plan-form of Option Agreement

 Exhibit 10.12 

 
 SYNAGEVA BIOPHARMA CORP. 

 
 2005 STOCK PLAN 

 
 STOCK OPTION AGREEMENT 

 
 1. Grant of Option. Synageva BioPharma Corp., a
Delaware corporation (the “Company”), hereby grants to [Name] (“Optionee”), an option (the “Option”) to purchase the total number of shares of Common Stock (the “Shares”) set forth
in the Notice of Stock Option Grant (the “Notice”), at the exercise price per Share set forth in the Notice (the “Exercise Price”) subject to the terms, definitions and provisions of the Synageva BioPharma Corp.
2005 Stock Plan (the “Plan”) adopted by the Company, which is incorporated in this Agreement by reference. Unless otherwise defined in this Agreement, the terms used in this Agreement shall have the meanings defined in the Plan.

  
 2. Designation of Option. This
Option is intended to be an Incentive Stock Option as defined in Section 422 of the Code only to the extent so designated in the Notice, and to the extent it is not so designated or to the extent the Option does not qualify as an Incentive
Stock Option, it is intended to be a Nonstatutory Stock Option. 
  
 Notwithstanding the above, if designated as an Incentive Stock Option, in the event that the Shares subject to this Option (and all other Incentive Stock Options granted to Optionee by the Company or any
Parent or Subsidiary, including under other plans of the Company) that first become exercisable in any calendar year have an aggregate fair market value (determined for each Share as of the date of grant of the option covering such Share) in excess
of $100,000, the Shares in excess of $100,000 shall be treated as subject to a Nonstatutory Stock Option, in accordance with Section 5(c) of the Plan. 
  

3. Exercise of Option. This Option shall be exercisable during its term in accordance with the Vesting/Exercise Schedule set
out in the Notice and with the provisions of Section 9 of the Plan as follows: 
  
 (a) Right to Exercise. 
  
 (i) This Option may not be exercised for a fraction of a share. 
  

(ii) In the event of Optionee’s death, disability or other termination of employment, the exercisability of the Option is governed
by Section 6 below, subject to the limitations contained in this Section 3. 
  
 (iii) In no event may this Option be exercised after the Expiration Date of the Option as set forth in the Notice. 

  
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 (b) Method of Exercise. 

 
 (i) This Option shall be exercisable by execution and
delivery of the Exercise Notice and Stock Purchase Agreement attached hereto as Exhibit A, or any other form of written notice approved for such purpose by the Company which shall state Optionee’s election to exercise the Option,
the number of Shares in respect of which the Option is being exercised, and such other representations and agreements as to the holder’s investment intent with respect to such Shares as may be required by the Company pursuant to the provisions
of the Plan. Such written notice shall be signed by Optionee and shall be delivered to the Company by such means as are determined by the Plan Administrator in its discretion to constitute adequate delivery. The written notice shall be accompanied
by payment of the Exercise Price. This Option shall be deemed to be exercised upon receipt by the Company of such written notice accompanied by the Exercise Price. 

 
 (ii) As a condition to the exercise of this Option and as
further set forth in Section 11 of the Plan, Optionee agrees to make adequate provision for federal, state or other tax withholding obligations, if any, which arise upon the vesting or exercise of the Option, or disposition of Shares, whether
by withholding, direct payment to the Company, or otherwise. 
  
 (iii) The Company is not obligated, and will have no liability for failure, to issue or deliver any Shares upon exercise of the Option unless such issuance or delivery would comply with the Applicable
Laws, with such compliance determined by the Company in consultation with its legal counsel. This Option may not be exercised if the issuance of such Shares upon such exercise or the method of payment of consideration for such shares would
constitute a violation of any applicable federal or state securities or other law or regulation, including any rule under Part 221 of Title 12 of the Code of Federal Regulations as promulgated by the Federal Reserve Board. As a condition
to the exercise of this Option, the Company may require Optionee to make any representation and warranty to the Company as may be required by the Applicable Laws. 

 
 4. Method of Payment. Payment of the Exercise
Price shall be by any of the following, or a combination of the following, at the election of Optionee: 
  

(a) cash; or 
  

(b) check. 
  

5. Forfeiture. This Option (whether or not vested or exercisable) is subject to forfeiture, termination and rescission, and
Optionee will be obligated to return to the Company the value received with respect to the Option (including Shares delivered under this Option, and any gain realized on a subsequent sale or disposition of Shares), (a) upon or in connection
with (i) a breach by Optionee of a non-competition, non-solicitation, confidentiality or similar covenant or agreement with the Company or its subsidiaries or (ii) an overpayment to Optionee of incentive compensation due to inaccurate
financial data, (b) in accordance with Company policy relating to the recovery of erroneously-paid incentive compensation, as such policy may be amended and in effect from time to time, or (c) as otherwise required by law or applicable
stock exchange listing standards, including, without limitation, the Dodd-Frank Wall Street 

  
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Reform and Consumer Protection Act. By accepting this Option, Optionee agrees to return the full amount required under this Section 5 at such time and in such manner as the Plan
Administrator shall determine in its sole discretion and consistent with applicable law. Neither the Plan Administrator nor the Company will be responsible for any adverse tax or other consequences to Optionee that may arise in connection with this
Section 5. 
  
 6. Termination of
Relationship. Following the date of termination of Optionee’s Continuous Service Status for any reason (the “Termination Date”), Optionee may exercise the Option only as set forth in the Notice and this Section 6.
To the extent that Optionee is not entitled to exercise this Option as of the Termination Date, or if Optionee does not exercise this Option within the Termination Period set forth in the Notice or the termination periods set forth below, the Option
shall terminate in its entirety. In no event, may any Option be exercised after the Expiration Date of the Option as set forth in the Notice. 
  

(a) Termination. In the event of termination of Optionee’s Continuous Service Status other than as a result of
Optionee’s disability or death or for Cause (as defined in the Plan), Optionee may, to the extent Optionee is vested in the Option Shares at the Termination Date, exercise this Option during the Termination Period set forth in the Notice.

  
 (b) Other Terminations. In
connection with any termination other than a termination covered by Section 6(a), Optionee may exercise the Option only as described below: 
  

(i) Termination upon Disability of Optionee. In the event of termination of Optionee’s Continuous Service Status as a
result of Optionee’s disability, Optionee may, but only within six months from the Termination Date, exercise this Option to the extent Optionee was vested in the Option Shares as of such Termination Date. 

 
 (ii) Death of Optionee. In the event of the
death of Optionee (a) during the term of this Option and while an Employee of the Company and having been in Continuous Service Status since the date of grant of the Option, or (b) within thirty (30) days after Optionee’s
Termination Date, the Option may be exercised at any time within twelve months following the date of death by Optionee’s estate or by a person who acquired the right to exercise the Option by bequest or inheritance, but only to the extent
Optionee was vested in the Option as of the Termination Date. 
  
 (iii) Termination for Cause. In the event Optionee’s Continuous Service Status is terminated for Cause, the Option shall terminate immediately upon such termination for Cause as set
forth in Section 9(b)(iv) of the Plan. In the event Optionee’s employment with the Company is suspended pending investigation of whether such relationship shall be terminated for Cause, all Optionee’s rights under the Option,
including the right to exercise the Option, shall be suspended during the investigation period, also as set forth in Section 9(b)(iv) of the Plan. 
  

7. Non-Transferability of Option. This Option may not be transferred in any manner otherwise than by will or by the laws of
descent or distribution and may be exercised during the lifetime of Optionee only by him or her. The terms of this Option shall be binding upon the executors, administrators, heirs, successors and assigns of Optionee. 

  
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 8. Notice of Disqualifying Disposition. With respect to any Shares issued upon
exercise of an Incentive Stock Option, if Optionee sells or otherwise disposes of such Shares on or before the later of (i) the date two years after the Option grant date, or (ii) the date one year after the date of exercise, Optionee
shall immediately notify the Company in writing of such disposition. 
  
 9. Change of Control Acceleration. In the event of a Change of Control the outstanding awards are not being assumed or substituted by the Successor Corporation in connection with the
transaction, the vesting and exercisability of this Option shall accelerate such that this Option shall become fully vested and exercisable, effective as of immediately prior to consummation of the transaction. The Company shall notify the Optionee
or holder of such Change of Control at least ten (10) days prior to the date of Change of Control. To the extent that this Option is not exercised prior to consummation of a Change of Control in which this Option is not being assumed or
substituted, this Option shall terminate upon the consummation of the Change of Control transaction. 
  

In the event (i) of a Change of Control, and (ii) Optionee is a Participant holding an option assumed or substituted by the
Successor Corporation in the Change of Control, and Optionee is involuntarily terminated by the Successor Corporation without Cause (not including death or disability) at the time of, or within one (1) year following consummation of, the Change
of Control transaction, then any assumed or substituted option held by the terminated Optionee at the time of termination shall fully accelerate and become exercisable. The acceleration of vesting provided for in the previous sentence shall occur
immediately prior to the effective date of termination of Optionee’s Continuous Service Status. 
  

If any payment or benefit an Optionee would receive pursuant to a Change of Control from the Company or otherwise (“Payment”)
would (i) constitute a “parachute payment” within the meaning of Section 280G of the Code, and (ii) but for this sentence, be subject to the excise tax imposed by Section 4999 of the Code (the “Excise Tax”),
then such Payment shall be equal to the Reduced Amount. The “Reduced Amount” shall be either (x) the largest portion of the Payment that would result in no portion of the Payment being subject to the Excise Tax or (y) the largest
portion, up to and including the total, of the Payment, whichever amount, after taking into account all applicable federal, state and local employment taxes, income taxes, and the Excise Tax (all computed at the highest applicable marginal rate),
results in Optionee’s receipt, on an after-tax basis, of the greater amount of the Payment notwithstanding that all or some portion of the Payment may be subject to the Excise Tax. If a reduction in payments or benefits constituting
“parachute payments” is necessary so that the Payment equals the Reduced Amount, reduction shall occur in the following order: reduction of cash payments; cancellation of accelerated vesting of Stock Awards; reduction of employee benefits.
In the event that acceleration of vesting of Stock Award compensation is to be reduced, such acceleration of vesting shall be cancelled in the reverse order of the date of grant of Optionee’s Stock Awards (i.e., earliest granted Stock Award
cancelled last) unless Optionee elect in writing a different order for cancellation. 
  
 The accounting firm engaged by the Company for general audit purposes as of the day prior to the effective date of the Change of Control shall perform the foregoing calculations. If the accounting firm so
engaged by the Company is serving as accountant or auditor for the 

  
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individual, entity or group effecting the Change of Control, the Company shall appoint a nationally recognized accounting firm to make the determinations required hereunder. The Company shall
bear all expenses with respect to the determinations by such accounting firm required to be made hereunder. 
  

The accounting firm engaged to make the determinations hereunder shall provide its calculations, together with detailed supporting
documentation, to Optionee and the Company within fifteen (15) calendar days after the date on which Optionee’s right to a Payment is triggered (if requested at that time by Optionee or the Company) or such other time as requested by
Optionee or the Company. If the accounting firm determines that no Excise Tax is payable with respect to a Payment, either before or after the application of the Reduced Amount, it shall furnish Optionee and the Company with an opinion reasonably
acceptable to Optionee and Company that no Excise Tax will be imposed with respect to such Payment. Any good faith determinations of the accounting firm made hereunder shall be final, binding and conclusive upon Optionee and the Company. 

 
 10. Effect of Agreement. Optionee acknowledges
receipt of a copy of the Plan and represents that he or she is familiar with the terms and provisions thereof (and has had an opportunity to consult counsel regarding the Option terms), and hereby accepts this Option and agrees to be bound by its
contractual terms as set forth herein and in the Plan. Optionee hereby agrees to accept as binding, conclusive and final all decisions and interpretations of the Plan Administrator regarding any questions relating to the Option. In the event of a
conflict between the terms and provisions of the Plan and the terms and provisions of the Notice and this Agreement, the Plan terms and provisions shall prevail. The Notice and the Option, including the Plan, constitutes the entire agreement between
Optionee and the Company on the subject matter hereof and supersedes all proposals, written or oral, and all other communications between the parties relating to such subject matter. 
  
 [Signature Page Follows] 

  
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 This Agreement may be executed in two or more counterparts, each of which shall be deemed an
original and all of which together shall constitute one document. 
  

			
	 THE COMPANY:
  

Synageva BioPharma Corp.

		
	By:	 	 
		 	(Signature)
	 Name:
 Title:
	 	 Sanj K. Patel

President & CEO

  

	
	OPTIONEE:
	
	 
	Name of Optionee:First Amendment to Lease Agreement dated November 29, 2011

 Exhibit 10.19 
 FIRST AMENDMENT TO LEASE 
 THIS FIRST AMENDMENT
TO LEASE is made this 29th day of November, 2011, by and
between ONE LEDGEMONT LLC (“Landlord”) and SYNAGEVA BIOPHARMA CORP. (“Tenant”). 

BACKGROUND: 
 A. Reference is made to a certain Lease dated April 8, 2010, by and between Landlord and Tenant (the “Lease”) demising certain space on the 500 Level of Building B and the 500
Level of Building C of the Ledgemont Development Center, 128 Spring Street, Lexington, Massachusetts (the “Existing Premises”). Capitalized terms used but not defined herein shall have the same meaning as in the Lease. 

B. Landlord and Tenant are the current holders, respectively, of the lessor’s and lessee’s interests in the Lease, 

C. Landlord and Tenant now desire to amend the Lease as set forth herein. 

AGREEMENTS: 
 NOW, THEREFORE, in consideration of the mutual covenants and agreements herein contained, and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged,
Landlord and Tenant hereby agree and amend the Lease as follows: 
 1. Expansion Space. Upon the substantial completion
of Landlord’s Work (the “Expansion Space Commencement Date”), which is anticipated to be on or about December 15, 2011 (however, in the event of a delay in the Expansion Space Commencement Date, Tenant shall not
have any claim against Landlord, and Landlord shall have no liability to Tenant, by reason thereof), approximately 3,730 rentable square feet of space on the first floor of The Richards House, 500 Level shown on the plan attached hereto as
Exhibit A-1 (such space, hereinafter referred to as the “Expansion Space”) shall be deemed added to and incorporated into the Premises demised under the Lease. Additionally, Tenant shall have the exclusive license to use the
area known as the upper floors of The Richards House for general office and storage use only (the “As Is Space”) at no additional cost and Tenant shall not sublet, assign, transfer or otherwise convey or encumber this license, and
shall not permit or suffer any other person or entity to use or occupy all or any part of the As Is Space. Upon the Expansion Space Commencement Date, all references to the Premises in the Lease shall include the Expansion Space, and all references
to Exhibit A in the Lease shall be deemed to include and refer to Exhibit A-1. The Expansion Space shall be delivered free of all occupants, personal property, trade fixtures and equipment and, except as expressly provided herein,
shall be accepted by Tenant in “as-is”, “where-is” condition without any warranty of fitness for use or occupancy, expressed or implied; and Tenant agrees that, except for Landlord’s Work, Landlord has no work to perform in
or on the Expansion Space to prepare same for Tenant’s use and occupancy, and that any work to be done in or on the Expansion Space in addition to Landlord’s Work will be performed by Tenant at Tenant’s sole cost and expense in
accordance with the terms and conditions of the Lease. 
 2. Use. The Expansion Space shall be used for general office
use and for no other purpose. 

 3. Landlord’s Work. Landlord shall substantially complete the work shown on
Exhibit B attached hereto (the “Landlord’s Work”). Landlord’s Work shall be completed using building standard materials and finishes, where applicable, in a good and workmanlike manner and in compliance with all
legal requirements. Landlord shall pay the costs and expenses relating to the completion of Landlord’s Work. Landlord shall use good faith efforts to mitigate interference caused by the completion of Landlord’s Work with Tenant’s use
and occupancy of the Premises, but entry into or about the Premises or performance of work necessary to complete Landlord’s Work shall not give rise to any claim for a rent abatement, constructive eviction, or any other damage or remedy.
Landlord’s Work shall be deemed “substantially” completed and finally approved and accepted by the parties when Landlord’s Work has been completed except for minor items, adjustments or defects that can be completed or remedied
after Tenant occupies the Expansion Space without causing substantial interference with Tenant’s use thereof. Landlord shall provide to Tenant a fully signed-off building permit and/or a permanent (or temporary) certificate of occupancy, to the
extent required by the Town of Lexington, with respect to Landlord’s Work. If either the substantial completion of Landlord’s Work or the Expansion Space Effective Date shall be delayed due to Tenant Delays (as defined below), the
Expansion Space Effective Date shall be deemed to have occurred on the date such substantial completion would have occurred but for such Tenant Delays. Landlord shall not be liable to Tenant if the substantial completion of Landlord’s Work is
delayed as a result of any Tenant Delays. For purposes of this Section, Tenant Delays shall mean delays from any of the following causes: (i) Tenant’s failure to respond to any requests or submissions relating to Landlord’s Work
and/or any of the construction documents relating thereto within five (5) business days of request; (ii) any material change in the construction documents caused by Tenant once finally approved and accepted by the parties, even though
Landlord may approve such change; (iii) any request by Tenant for a delay in the commencement or completion of Landlord’s Work for any reason; or (iv) any other material delay in substantial completion of Landlord’s Work directly
attributable to the acts or omissions of, or breach of this Lease by, Tenant, its employees, agents, or contractors. 
 4.
Base Rent. From and after the Expansion Space Commencement Date through August 31, 2012, Base Rent shall consist of the Base Rent payable under the Lease per month for the Existing Premises for the same period plus $5,595.00 per month
for the Expansion Space (for a total monthly amount of $23,928.33). Commencing on September 1, 2012 Base Rent shall consist of the Base Rent payable under the Lease per month for the Existing Premises for the same period plus $5,905.83 per
month for the Expansion Space (for a total monthly amount of $25,155.83). From and after the Expansion Space Commencement Date the table below shall be added to the Base Rent section of Article 1 of the Lease and the Base Rent for the Expansion
Space shall be as set forth in the table below: 
  

													
	 Period
	  	RSF	 	  	Base Rent	 	  	Monthly
Installment
of Base
Rent	 
	 Expansion Space Commencement Date – August 31, 2012
	  	 	3,730	  	  	$	67,140.00	  	  	$	5,595.00	  
	 September 1, 2012 – August 31, 2013
	  	 	3,730	  	  	$	70,869.96	  	  	$	5,905.83	  

  
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 6. Operating Costs and Tax Escalation. From and after the Expansion Space
Commencement Date, for purposes of calculating the Tenant’s Pro Rata Share of the increase in taxes and operating expenses with respect to the Expansion Space only, the Operating Costs Base Year shall be Calendar Year 2012 (the
“Operating Cost Base Year”) and the Tax Base Year shall be Calendar Year 2012 (the “Tax Base Year”). Additionally, the Tax Base shall reflect the Taxes for the Expansion Space during the Tax Base Year (the
“Tax Base”) and shall apply to a Tax Period of twelve (12) months (the “Tax Period”). Tax Base shall be reduced pro rata if and to the extent that the Tax Period contains fewer than twelve (12) months.

 7. Tax Excess. With respect to the Expansion Space only, Tenant shall pay to Landlord, with respect to any Tax Period,
Tenant’s Pro Rata Share of the amount (if any) by which the Taxes for the Expansion Space for such Tax Period exceeds the Tax Base, such sum being hereinafter referred to as “Tax Excess”. Tax Excess shall be due when billed by
Landlord. In implementation and not in limitation of the foregoing, Tenant shall remit to Landlord pro rata monthly installments on account of projected Tax Excess, calculated by Landlord on the basis of the most recent Tax data or budget available.
If the total of such monthly remittances on account of any Tax Period is greater than the actual Tax Excess for such Tax Period, Tenant may credit the difference against the next installment of rent or other charges due to Landlord hereunder. If the
total of such remittances is less than the actual Tax Excess for such Tax Period, Tenant shall pay the difference to Landlord when billed therefor. Appropriate credit against Tax Excess shall be given for any refund obtained by reason of a reduction
in any Taxes by the Assessors or the administrative, judicial or other governmental agency responsible therefor. The original computations, as well as reimbursement or payments of additional charges, if any, or allowances, if any, under this First
Amendment shall be based on the original assessed valuations with adjustments to be made at a later date when the tax refund, if any, shall be paid to Landlord by the taxing authorities. Expenditures for legal fees and for other similar or
dissimilar expenses incurred in obtaining the tax refund may be charged against the tax refund before the adjustments are made for the Tax Period. 
 8. Operating Expense Excess. With respect to the Expansion Space only, Tenant shall pay to Landlord, with respect to any Operating Year, Tenant’s Proportionate Share of the amount (if any) by
which Operating Costs for the Expansion Space only for such Operating Year exceeds Operating Costs in the Operating Costs Base Year, such sum being hereinafter referred to as “Operating Expense Excess”. In determining Operating Costs in
the Operating Costs Base Year, there shall be excluded from the Operating Costs for said Operating Costs Base Year any nonrecurring Operating Costs. In implementation and not in limitation of the foregoing, Tenant shall remit to Landlord pro rata
monthly installments on account of projected Operating Expense Excess, calculated by Landlord on the basis of the most recent Operating Costs date or budget available. If the total of such monthly remittances on account of any Operating Year is
greater than the actual Operating Expense Excess for such Operating Year, Tenant may credit the different against the next installment of rent or other charges due to Landlord hereunder. If the total of such remittances is less than actual Operating
Expense Excess for such Operating Year, Tenant shall pay the difference to Landlord when billed therefor. 
 9. Part
Years. If the Expansion Space Commencement Date or the Termination Date occurs in the middle of an Operating Year or Tax Period, Tenant shall be liable for only that portion of the Operating Expense Excess or Tax Share Excess, as the case may
be, in respect of such Operating Year or Tax Period represented by a fraction, the numerator of which is the number of days of the herein term which falls within the Operating Year or Tax Period and the denominator of which is three hundred
sixty-five (365), or the number of days in said Tax Period, as the case may be. 

  
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 10. Tenant’s Pro Rata Share. From and after the Expansion Space Commencement
Date through August 31, 2013, Tenant’s Pro Rata Share for purposes of determining Tenant’s share of Tax Excess and Operating Expense Excess with regard to the Expansion Space only shall be equal to 2.14%. Additionally, Article 1 of
the Lease is hereby amended so that Tenant’s Pro Rata Share is equal to 8.44% for all other purposes under the Lease, including Tenant’s liability for Additional Rent which liability shall remain unchanged. 

11. Parking. The number of parking spaces set forth in Sections 2.01 (d)(i) and 2.01(d)(ii) of the Lease is hereby amended as
follows: As of the Expansion Space Commencement Date, Tenant shall have the appurtenant right to use, free of additional charge, up to 10 additional unreserved parking spaces on the Property for standard size automobiles and small utility vehicles;
of which two (2) parking spaces shall be located in the parking area in front of Richards House. The locations of such parking spaces are subject to change from time to time pursuant to the Lease. 

12. Signage. From and after the Expansion Space Commencement Date, Tenant shall have the non-exclusive right, at its sole cost and
expense, to maintain one (1) exterior sign on the Richards House for the purpose of identifying Tenant, which sign (including size, logo, color(s) and degree of illumination, if any, and location on the Building) shall be subject to the prior
written approval of Landlord, not to be unreasonably withheld or delayed and installed and maintained in compliance with all applicable Laws and Restrictions. Tenant shall be responsible for obtaining and maintaining all necessary permits and
approvals for such signage, along with all costs and expenses incurred by Landlord in connection therewith (including any taxes or assessments thereon and the cost of providing and maintaining electrical service thereto) and Landlord shall
reasonably cooperate with Tenant in connection with obtaining such permits and approvals. Additionally, Tenant shall have the one-time right at its cost and expense, to relocate the existing monument sign entitled Richards House. Any relocation of
said monument sign and the manner in which said monument sign is moved shall be subject to the prior written approval of Landlord, not to be unreasonably withheld or delayed. Tenant shall have the non-exclusive right, at its expense, to maintain a
sign panel on said monument sign (which may rename said monument sign Synageva Biopharma) which sign panel (including size, design, color(s) and degree of illumination (if any) and location on the monument) shall be subject to the prior reasonable
approval of Landlord and in compliance with all applicable Laws and Restrictions. Tenant shall exercise its right hereunder in compliance with all Laws and Restrictions and shall obtain, at its cost and expense, all necessary permits and approvals
necessary to remove the existing, and thereafter erect and maintain a new, monument sign (and Tenant’s sign panel thereon). Upon the expiration or termination of this Lease, Tenant shall, at its sole cost and expense, remove Tenant’s
identification panel on the monument sign and repair and restore the monument (and any holes or other damage thereto) to its original condition. Tenant shall be responsible for any damage or repairs to the Building and the monument sign related to
the erection, maintenance or removal of its sign panel, unless caused by the negligence or willful misconduct of Landlord. 

13. Brokers. Landlord and Tenant each warrant and represent to the other that they have dealt with no brokers in connection with
the negotiation or consummation of this First Amendment other than FHO Partners and CB Richard Ellis (collectively, the “Brokers”) and in the event of any brokerage claim against either party by any person claiming to have dealt with
either Landlord or Tenant in connection with this First Amendment, other than the Brokers, the party with whom such person claims to have dealt shall defend and indemnify the other party against such claim. Landlord shall pay any commission due the
Broker pursuant to a separate agreement. 

  
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 14. Reaffirmation. In all other respects the Lease shall remain unmodified and shall
continue in full force and effect, as amended hereby. The parties hereby ratify, confirm, and reaffirm all of the terms and conditions of the Lease, as amended hereby. 
 [Signatures Follow] 

  
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 IN WITNESS WHEREOF the parties hereto have executed this First Amendment to Lease on the
date first written above in multiple copies, each to be considered an original hereof, as a sealed instrument. 
  

									
	LANDLORD:	 		 	TENANT:
			
	ONE LEDGEMONT LLC,	 		 	SYNAGEVA BIOPHARM, CORP.
			
	a Delaware limited liability company	 		 	a Delaware corporation
					
	By:	 	 

	 		 	By:	 	 

		 	Robert L. Beal, its authorized signatory	 		 		 	Name: Sanj K. Patel
		 		 		 		 	Title: Chief Executive Officer and President

  
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 EXHIBIT A-1 
 EXPANSION SPACE 

  
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 FLOOR PLAN 

 
 

 

  
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 Exhibit B 
 Plans and Specifications for Landlord’s Work 
 Richards House

 Note: All applicable state and local codes will be adhered to. Subject to the other terms and conditions of this Lease,
including Section 10.01, unless specifically noted all items to be assumed in as-is condition, provided however that all MEP systems will be in good working order at commencement of the lease. 

Landlord shall deliver the Premises in accordance with Landlord’s Work, which shall include, without limitation, the following:

  

	 	1)	Partitions/drywall- Demo and reconstruction of drywall as shown on the plan dated 9/9/11. 

 

	 	2)	Ceilings- Existing sheetrock ceilings to be patched as necessary. 

  

	 	3)	HVAC systems to be in good working order throughout Richards House including new diffusers where necessary to provide industry standard office temperatures.

  

	 	4)	 Electrical/Lighting-Recessed can lighting where accessible with supplemental 2’x 2’ or 2’x 4’ surface mounted fixtures where
necessary on the 1st Floor to include restroom. Electrical
outlets will be provided throughout office space. 

  

	 	5)	Voice/Data/Card Access & Security systems - Responsibility of tenant. 

 

	 	6)	 Flooring- New VCT tile to be installed in 1st Floor bathroom, new carpet to be installed throughout the 1st Floor office area and extend down the corridor to include the reception area. Carpet to be consistent or closest match
with Synageva 500 C Bldg Executive office space and to not exceed $26/yd. 26 oz. Broadloom: Commercial Nylon, Pattern Loop, Solution 5/32 Pile Height on Standard Action 

 

	 	7)	 Plumbing- New faucet to be installed in existing 1st Floor restroom pedestal sink. New mirror. 

 

	 	8)	 Doors, Hardware- (4) New doors and hardware on 1st Floor to be consistent or equivalent match with 500 C Bldg Executive office space. Card access installation to be the
responsibility of the Tenant. 

  

	 	9)	 Windows & Blinds- Blinds to be replaced for all window areas on 1st floor and to be consistent with the blinds currently in place. 

 

	 	10)	Paint- Typical office paint to be used in office space, on all new drywall in premises and existing walls. Paint interior window frames in the area of Offices 1,
2, & 3. 

  
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	 	11)	Fire protection- Sprinkler heads to be relocated as needed based on the new layout. Main sprinkler piping to remain as-is. 

 

	 	12)	Furniture- Office furniture both onsite and offsite to be responsibility of Tenant to relocate/move within the premises. 

All modifications or changes to these specifications must be requested in writing by the Tenant to the Landlord, shall be subject to Landlord approval
and shall be at Tenant’s sole expense. 
 With the exception of the above and as shown on the space plan, the Premises will be turned over
in it’s as-is condition. Landlord’s Work will not include portable fixtures, equipment, furnishing, and other special purpose items and equipment. 

  
 10

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00201-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00201-of-00352.parquet"}]]