Document:

AMENDMENT
      TO EMPLOYMENT
      AGREEMENT

     

    THIS
      AGREEMENT, dated as of March 1, 2006, is by and between AGU Entertainment Corp.,
      a Delaware corporation (the “Company”) and Less Garland
      (“Employee”).

     

    WHEREAS,
      on or about August 14, 2003, Employee entered into an Employment Agreement
      (the
“Employment Agreement”) with Pyramid Music Corp. Which the parties hereto now
      wish to amend;

     

    NOW
      THEREFORE, for and in consideration of the mutual promises and covenants made
      by
      each of the parties, the parties agree to amend the said Employment Agreement
      as
      follows:

     

    1.  Incorporation
      of Recitals. The above Recitals are incorporated by reference into this
      Agreement.

     

    2.  Employment
      Term. Paragraph 1 of the said Employment Agreement shall be amended to extend
      the term of employment for an additional two (2) years from the date of
      execution of this Agreement. The parties may extend the term thereafter upon
      mutual consent.

     

    3.  Position,
      Duties. Employee shall be employed by Company as the Chief Executive officer
      (CEO) of The Tube Music Network. Inc. (“The Tube”). Throughout his employment
      with Company, Employee shall serve as Senior Executive Vice President of the
      Company. In addition, Employee shall report directly to the Board of Directors
      of the Company and not
      to
      any officer of the Company. Any provisions in Paragraph 2 of the said Employment
      Agreement to the contrary are hereby revoked and null.

     

    4.  Compensation.
      Employee’s base salary as described in Paragraph 3 of the said Employment
      Agreement was increased, effective July 1, 2005, to $450,000 per annum. In
      connection with the execution hereof, Employee shall be paid a $50,000 bonus
      as
      Employee has reached certain milestones as to the number of households reached
      by The Tube, Company to pay $25,000 on or before June 1, 2006, and the balance
      of $25,000 on or before December 1, 2006. Effective January 1, 2007, Employee’s
      base salary shall be increased to $550,000 per annum. Effective January 1,
      2008,
      Employee’s base salary shall be increased to $650,000 per annum.

     

    5.  Additional
      Benefits. In addition to all benefits and compensation due Employee, Company
      shall pay to Employee the following bonus compensation, the below-described
      subparagraph (i) bonus payable by or within ninety (90) days, but no less often
      than quarterly, from the date of Company’s receipt of the income and revenues
      from which this additional compensation is based as hereinafter described and
      the below-described subparagraph (ii) bonus payable by or within ninety (90)
      days from the end of the Company’s fiscal year:

     

    (i)  Beginning
      as of May 1, 2006 and continuing throughout the term of Employee’s employment
      and for two (2) years after Employee’s termination from Company or The Tube,
      Employee shall receive a bonus equal to four percent (4%) of all advertising
      and
      merchandising revenues, net of any advertising agency commissions, collected
      by
      Company or The Tube from any source; and

     

     

    
      
         

      

      
         

        
          

        

      

      
         

      

    

     

    (ii)  Beginning
      as of May 1, 2006, and continuing throughout the term of Employee’s employment
      and for two (2) years after Employee’s termination from Company, Employee shall
      receive a bonus equal to four percent (4%) of EBITDA figured on the Company’s
      annual aggregate revenues (defined as revenues recognized by the Company and
      all
      of its controlled or wholly owned subsidiaries, including but not limited to
      The
      Tube).

     

    (iii)  Employee
      shall have, at all times, a right of audit to verify any and all amounts paid
      to
      him under paragraph 5 as described above. Company shall pay Employee an auto
      allowance of $1500 per month beginning in the month the Company executes any
      distribution or other agreements with Tribune and/or Sinclair concerning The
      tube, as previously agreed in writing.

     

    (iv)  Employee
      shall have the right to enter into a private stock purchase of shares of stock
      in the Company between Employee and any other officer of the Company at a price
      below market so long as Employee agrees to be bound by a restriction prohibiting
      future sale of any such stock for a term of two (2) years after the date of
      any
      such purchase. Company agrees to pay for all costs related to the registration
      of that stock or any other shares of stock owned by Employee in the Company.
      Company agrees to register, at Company’s own cost, any stock owned by Employee
      as described in paragraph 6 below by or within hundred twenty (120) days from
      the date of execution hereof.

     

    6.  Stock.
      Company acknowledges that it issued on or about March 2004 to Employee 1,500,000
      shares of stock. Company hereby grants to Employee piggyback registration rights
      for all unregistered shares of stock owned by Employee on the next stock
      registration statement filed by Company or within 120 days, whichever occurs
      first.

     

    7.  Benefits.
      The Company agrees to use its best efforts to obtain and maintain directors
      and
      officers liability insurance coverage during and throughout the term of
      Employee’s employment.

     

    8.  Termination.
      The “Severance Period” as set forth in Paragraph 6 of said “Employment
      Agreement” shall be extended and redefined to mean 24 months from the date of
      termination of Employee’s employment.

     

    9.  Additional
      Covenants.

     

    a.  Company
      hereby authorizes Employee to locate and select reasonable and necessary offices
      for The Tube at the earliest possible date.

     

    b.  In
      addition to the provisions in paragraph 9(a) above, Company agrees to bring
      all
      accounts payable for The Tube current immediately, and to remain current on
      all
      expense reimbursements and other monies owed as of the execution hereof to
      Employee, including the monthly $4,000 reimbursements due for Employee’s
      administrative assistant. After the funding of The Tube required by Paragraph
      9(a) above, Employee shall have the authority to disburse funds for all such
      expense reimbursements and costs of administration.

     

     

    
      
         

      

      
        2

        
          

        

      

      
         

      

    

    
 

    c.  Company
      may offer Employee additional and other stock options in accordance with the
      Company’s employee benefits plans.

     

    d.  Employee
      shall earn performance bonuses as follows: (i) When The Tube’s revenues first
      equal or exceed its expenses for six (6) consecutive months, Company shall
      pay
      to Employee the sum of $500,000; and (ii) when The Tube’s annual profits first
      equal or exceed the sum of $2,500,000 (Two Million Five Hundred thousand
      dollars), Company shall pay to Employee the sum of $500,000; and (iii) when
      The
      Tube’s annual profits first equal or exceed $5,000,000 (five million dollars),
      Company shall pay to Employee the sum of $500,000.

     

    10.  MISCELLANEOUS
      PROVISIONS.

     

    a.  All
      provisions of the said Employment Agreement not amended, changed or altered
      by
      this Agreement, shall remain in full force and effect.

     

    b.  Any
      prior
      oral agreements between the parties hereto not included herein are superseded
      by
      this Agreement.

     

    c.  This
      Agreement shall not be amended or modified save by a writing signed by all
      parties.

     

    d.  This
      Agreement shall be interpreted and construed under the laws of the State of
      Florida, and venue for all suits arising out of or related to this Agreement
      shell be brought in a court of competent jurisdiction in Florida.

     

    e.  This
      Agreement is binding upon and shall inure to the benefit of each of the parties,
      including their respective executors, administrators, heirs, successors and
      assigns.

     

    f.  The
      prevailing party in any action brought to enforce any provisions of this
      Agreement shall be entitled to recover reasonable attorneys fees.

     

    g.  Should
      any provision thereof be deemed to be invalid or illegal, such provision shall
      be stricken from this Agreement and shall not affect any other provision of
      this
      Agreement.

     

    h.  Each
      party to bear their own costs in preparation of this writing.

     

    i.  Any
      corporate party hereto warrants that it is a corporation in good standing and
      exists validly and that the person signing below on behalf of the said corporate
      party has been properly and duly authorized to sign and bind the said corporate
      party hereto.

     

    
      	
              SIGNED
                as of the effective date above;

            	 
	 	 
	 	 
	
              /s/
                John Poling             
 /s/
                David
                Levy

            	 
	
              COMPANY:
                by John Polling, CFO and David Levy, President

            	 
	 	 
	
              
                /s/
                  Les Garland

              

            	 

    

    
      	
              EMPLOYEE:
                by Les Garland

            	 

    

     

     

     

    
      
         

      

        3EXHIBIT 10.22

                                 FIRST AMENDMENT
                                       TO
                          REGISTRATION RIGHTS AGREEMENT

      This FIRST AMENDMENT TO REGISTRATION RIGHTS AGREEMENT (this "Amendment")
is made and entered into effective as of December 31, 2005, by and among
BIONOVO, INC., a Delaware corporation (formerly Lighten Up Enterprises
International, Inc., a Nevada corporation) ("Pubco"), and the other parties
signatory hereto.

                                    RECITALS

      A. The parties hereto previously have entered into that certain
Registration Rights Agreement dated effective April 6, 2005 ("Original
Agreement"), which agreement provided for, among other things, the mandatory
registration (as more fully described in the Original Agreement, the "Mandatory
Registration") for resale of shares of common stock of Pubco and shares of Pubco
common stock underlying warrants (as more fully described in the Original
Agreement, the "Pubco Warrants") acquired by the Purchasers (as defined in the
Original Agreement) as of April 6, 2005 and liquidated damages in the event such
registration was not timely accomplished and maintained (as more fully described
in the Original Agreement, the "Liquidated Damages");

      B. Pubco has registered such shares of Pubco common stock on a
registration statement on Form SB-2 (File No. 333-126399, the "Effective
Registration Statement"), declared effective by the Securities and Exchange
Commission ("SEC") on November 2, 2005;

      C. As a consequence of the Mandatory Registration obligations and
Liquidated Damages provisions, Pubco has been required under Generally Accepted
Accounting Principles to record a liability on its balance sheet relating to the
Pubco Warrants and an expense on its statement of operations reflecting the
change in fair value of such warrant liability;

      D. It is the belief of Pubco's management that such warrant liability and
expense relating to the Mandatory Registration obligation and Liquidated Damages
provisions limits Pubco's opportunity to be listed on either the American Stock
Exchange or the NASDAQ SmallCap Market; and

      E. In order to permit Pubco to reclassify the accounting treatment of the
Pubco Warrants to additional paid in capital and thereby remove the
above-referenced warrant liability and expense from its balance sheet and
statement of operations, the parties hereto agree to amend the Original
Agreement to delete the Mandatory Registration obligation and the Liquidated
Damages provisions and in partial consideration therefor grant "piggy-back"
registration rights to the Holders, all upon the terms and conditions of this
Amendment;

      NOW, THEREFORE, in consideration of the foregoing and of the mutual
promises and covenants hereinafter set forth and of other good and valuable
consideration, the receipt and sufficiency of which are hereby acknowledged, the
parties agree as follows:

      SECTION 1. Defined Terms. Capitalized terms used in this Amendment but not
otherwise defined herein shall have the meanings ascribed to them in the
Original Agreement.
<PAGE>

      SECTION 2. Amendments.

            (a) The obligation of Pubco to register the Registrable Securities
pursuant to Section 2(a) of the Original Agreement is hereby amended to delete
such obligation of Pubco;

            (b) The Original Agreement is hereby amended to delete Section 2(b)
(Filing Default Liquidation Damages) and Section 2(c) (Effectiveness Default
Liquidation Damages) of the Original Agreement.

            (c) Notwithstanding the foregoing amendments, Pubco agrees to use
its commercially reasonable best efforts to maintain the effectiveness of the
Effective Registration Statement for the period specified in the Original
Agreement and the Holders shall remain obligated to satisfy their respective
obligations under the Original Agreement relating to the Effective Registration
Statement.

            (d) The Original Agreement is hereby amended to add the following
two subsections to Section 2 of the Original Agreement:

                  "(g) "Piggy-Back" Registration. If (but without any obligation
      to do so) Pubco proposes to register (including for this purpose a
      registration effected by Pubco for stockholders other than the Holders)
      any of its stock or other securities under the Securities Act in
      connection with the public offering of such securities solely for cash
      (other than a registration relating solely to the sale of securities to
      participants in Pubco stock plan, a registration with respect solely to a
      corporate reorganization or other transaction under Rule 145 of the
      Securities Act, a registration on any form which does not include
      substantially the same information as would be required to be included in
      a registration statement covering the sale of the Registrable Securities,
      or a registration in which the only Pubco Stock being registered is Pubco
      Stock issuable upon exercise of debt securities which are also being
      registered), Pubco shall, at such time, promptly give each Holder written
      notice of such registration. Upon the written request of each Holder given
      within twenty (20) days after mailing of such notice by Pubco, Pubco
      shall, subject to the provisions of Section 2(h), cause to be registered
      under the Securities Act all of the Registrable Securities that each such
      Holder has requested to be registered. The registration rights granted to
      a Holder pursuant to this paragraph shall terminate with respect to such
      Holder on the date when all of the Registrable Securities of such Holder
      covered by the Effective Registration Statement or an effective
      registration statement under this paragraph (a) have been sold pursuant to
      the Effective Registration Statement or such other registration statement
      or an exemption from the registration requirements of the Securities Act
      or (b) may be sold without any volume or other restrictions pursuant to
      Rule 144(k).

                  (h) Underwriting Requirements. In connection with any
      registered offering under Section 2 hereof involving an underwriting of
      shares of Pubco's capital stock, Pubco shall not be required to include
      any of the Holders' Registrable Securities in such underwriting unless
      they accept the terms of the underwriting as agreed upon between Pubco and
      the underwriters selected by it (or by other persons entitled to select
      the underwriters), and then only in such quantity as the underwriters
      determine in their sole discretion will not jeopardize the success of the
      offering by Pubco. If the total amount of securities, including

                                       2
<PAGE>

      Registrable Securities, requested by stockholders to be included in such
      offering exceeds the amount of securities that may be sold other than by
      Pubco that the underwriters determine in their sole discretion is
      compatible with the success of the offering, then Pubco shall be required
      to include in the offering only that number of such securities, including
      Registrable Securities, which the underwriters determine in their sole
      discretion will not jeopardize the success of the offering (the securities
      so included to be apportioned pro rata among the selling stockholders
      according to the total amount of securities entitled to be included
      therein owned by each selling stockholder or in such other proportions as
      shall mutually be agreed to by such selling stockholders, provided,
      however, that with respect to Pubco's IPO (defined below), all Registrable
      Securities may be excluded). For purposes of the preceding parenthetical
      concerning apportionment, for any selling stockholder which is a Holder of
      Registrable Securities and which is a partnership or corporation, the
      partners, retired partners and stockholders of such Holder, or the estates
      and family members of any such partners and retired partners and any
      trusts for the benefit of any of the foregoing persons shall be deemed to
      be a single "selling stockholder", and any pro-rata reduction with respect
      to such "selling stockholder" shall be based upon the aggregate amount of
      shares carrying registration rights owned by all entities and individuals
      included in such "selling stockholder", as defined in this sentence. The
      term "IPO" means the first underwritten public offering of Pubco's Stock
      registered under the Securities Act, other than a registration relating
      solely to a transaction under Rule 145 under the Securities Act or to an
      employee benefit plan of Pubco."

      SECTION 3. Effectiveness of Amendments. In accordance with Section 6(d) of
the Original Agreement, this Amendment shall not be effective unless and until
executed by Pubco and the Holders of at least sixty-six percent (66%) of the
outstanding Registrable Securities (assuming the exercise of all Pubco Warrants,
whether exercised or not).

      SECTION 4. Representations and Warranties.

            (a) Each of the undersigned parties (other than Pubco) hereby
affirms and remakes to Pubco all of the representations and warranties set forth
in the Subscription Agreement and in the Investor Questionnaire executed by such
party as of April 6, 2005.

            (b) Without limiting the generality of the foregoing, each of the
undersigned parties (other than Pubco) hereby represents and warrants to Pubco
that he, she or it is an "accredited investor" as that term is defined in Rule
501 of Regulation D promulgated under the Securities Act.

            (c) Each of the undersigned parties (other than Pubco) hereby
represents and warrants to Pubco that such party has read Pubco's Form SB-2 (SEC
File No. 333-126399), declared effective by the SEC on November 2, 2005, and the
prospectus contained therein as supplemented by Prospectus Supplement No. 1
dated November 14, 2005 and Prospectus Supplement No. 2 dated January 6, 2006,
and has been given the opportunity to ask any questions of and receive answers
from Pubco with respect thereto.

      SECTION 5. Ratification of Original Agreement. Except as modified by the
terms of this Amendment, the Original Agreement is hereby ratified and confirmed
in its entirety, and shall remain in full force and effect in accordance with
its terms.

                                       3
<PAGE>

      SECTION 6. Counterparts. This Amendment may be executed in one or more
counterparts, each of which shall be deemed an original, but all of which
together shall constitute one and the same instrument. Each party hereto
confirms that any facsimile copy of such party's executed counterpart of this
Amendment (or its signature page thereof) shall be deemed to be an executed copy
thereof.

      SECTION 7. Governing Law. This Amendment shall be governed by the laws of
the State of California (other than its rules of conflicts of law to the extent
that the application of the laws of another jurisdiction would be required
thereby).

      SECTION 8. Counsel. EACH OF THE UNDERSIGNED PARTIES ACKNOWLEDGES THAT HE,
SHE OR IT HAS BEEN ADVISED TO CONSULT SUCH PARTY'S LEGAL AND FINANCIAL ADVISORS
WITH RESPECT TO THE TERMS AND CONDITIONS OF THIS AMENDMENT AND HAS BEEN GIVEN
THE OPPORTUNITY TO DO SO.

      SECTION 9. Entire Agreement. The Original Agreement (including any and all
annexes, exhibits and schedules thereto), as amended by this Amendment,
constitute the entire agreement of the parties hereto with respect to the
subject matter thereof and hereof, and supersede all prior agreements and
understandings of the parties, oral and written, with respect to the subject
matter thereof and hereof.

      SECTION 10. Other General. The recitals hereto are a material part hereof
and are incorporated in this Amendment by reference as if fully set forth
herein. Captions and headings are for convenience only, are not deemed to be
part of this Amendment and shall not be used in the interpretation of this
Amendment.

                               [Signatures follow]

                                       4
<PAGE>

      IN WITNESS WHEREOF, the parties have executed this First Amendment to
Registration Rights Agreement effective as of the date first set forth above.

                                  PUBCO:

                                  BIONOVO, INC.
                                  (a Delaware corporation)

                                  By:_____________________________
                                  Name:___________________________
                                  Title:__________________________

                                       5
<PAGE>

      IN WITNESS WHEREOF, the parties have executed this First Amendment to
Registration Rights Agreement effective as of the date first set forth above.

                                  HOLDER:

                                  If Holder is an Entity:

                                  ______________________________________________
                                  Print Name of Entity

                                  By (signature):_______________________________
                                  Name (print):_________________________________
                                  Title:________________________________________

                                  If Holder(s) is an Individual(s):

                                  Signature:____________________________________
                                  Print Name:___________________________________

                                  Signature:____________________________________
                                  Print Name:___________________________________

                                       6

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00099-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00099-of-00352.parquet"}]]