Document:

<PAGE>
                                                                   EXHIBIT 10.04

[***] indicates the omission of confidential portions for which confidential
treatment has been requested. Such confidential information has been filed
separately with the Securities and Exchange Commission.

                               SECOND AMENDMENT TO
                           WHOLESALE SUPPLY AGREEMENT

This second amendment ("SECOND AMENDMENT") dated June 2, 2004 amends the
Wholesale Supply Agreement dated January 1, 2004 ("AGREEMENT") and subsequently
amended on May 26, 2004 between CVS and Cardinal Health. CVS and Cardinal Health
("PARTIES") desire to enter into this Second Amendment to amend Section 1 and
Section 12 Disclosure Schedule to include two (2) mail-order facilities being
acquired by CVS' affiliate PharmaCare Management Services Inc. ("PharmaCare")
located in Pittsburgh, Pennsylvania and Largo, Florida (MAIL-ORDER FACILITIES").

The Parties agree as follows:

     1.   Effective Date of Amendment. This Second Amendment shall be effective
          as of the date of the closing of the transaction pursuant to which CVS
          will purchase from J.C. Penney Company, Inc. ("JC PENNEY")
          approximately 1,260 retail pharmacies, approximately three (3)
          distribution centers, and approximately two (2) mail-order facilities
          located in Pittsburgh, Pennsylvania and Largo, Florida (to be acquired
          by CVS' affiliate PharmaCare from Eckerd Health Services) as publicly
          announced by CVS on April 5, 2004 ("TRANSACTION"). In the event that
          the Transaction does not close on or before September 1, 2004, then
          this Second Amendment shall become null and void and shall be of no
          force or effect. Furthermore, CVS reserves the right to provide
          Cardinal with notification ("NOTICE") before the close of the
          Transaction that CVS has determined in its sole discretion that it
          will not undertake the wholesale supply arrangement as described in
          the Second Amendment in which case this Second Amendment shall become
          null and void and shall be of no force or effect.

     2.   Scope. Notwithstanding anything else in the Agreement, as amended, in
          no event will CVS, at any time, be obligated to designate Cardinal as
          a primary means of pharmaceutical products replenishment for the
          Mail-order Facilities, if such Mail-order Facilities are subject to an
          existing wholesaler agreement which cannot be terminated by CVS or its
          affiliates for any reason, or which, if terminated by CVS or its
          affiliates in its business judgment, may result in breach of
          contractual obligations, termination penalties/fees of any type, or
          result in CVS or its affiliates compromising its business operations.

     3.   Disclosure Schedules. The Agreement is amended by deleting therefrom
          the following disclosure schedules in their entirety:

               "Section 1", and

                                        1

<PAGE>

               "Section 12 Disclosure Schedule"

          and replacing them with the following new Disclosure Schedules:

               "Section 1", and

               "Section 12 Disclosure Schedule"

          attached to this Second Amendment and incorporated into this Second
          Amendment and into the Agreement by this reference, which shall be
          attached by the Parties to their respective copies of the Agreement.

     4.   Generally. It is the Parties' intent for the Agreement and this
          Amendment (if the Transaction closes on or before September 1, 2004
          and CVS has not provided Cardinal with Notice before the close of the
          Transaction) to be applied and construed as a single instrument. The
          Agreement, as modified by this Second Amendment, remains in full force
          and effect and constitutes the entire agreement among the Parties
          regarding this subject matter and supersedes all prior or
          contemporaneous writings and understandings among the Parties with
          respect thereto. This Second Amendment will be binding on the Parties
          and their successor and assigns. If any term or provision of this
          Second Amendment is determined to be illegal or unenforceable by a
          court of competent jurisdiction, the remaining terms and provisions of
          this Second Amendment and the Agreement will remain in full force and
          effect. Only a subsequent writing signed by both Parties may amend
          this Second Amendment or further amend the Agreement.

CVS Pharmacy, Inc                       Cardinal Health*

By: /s/ Matthew J. Leonard              By: /s/ Michael J. Bender
    ---------------------------------       ------------------------------------
Print Name: Matthew J. Leonard          Print Name: Michael J. Bender
Title: VP Pharmacy Merchandising        Title: EVP, Retail Sales & Marketing

*The term "CARDINAL HEALTH" means the following pharmaceutical distribution
companies: Cardinal Health 106, Inc. (formerly known as James W. Daly, Inc.), a
Massachusetts corporation (Peabody, Massachusetts); Cardinal Health 103, Inc.
(formerly known as Cardinal Southeast, Inc.), a Mississippi corporation
(Madison, Mississippi); Cardinal Health 110, Inc. (formerly known as Whitmire
Distribution Corporation), a Delaware corporation (Folsom, California) and any
other subsidiary of Cardinal Health, Inc., an Ohio corporation ("CHI"), as may
be designated by CHI.

Cc: Tina Egan, Assistant General Counsel CVS
    Paul Williams, General Counsel Cardinal Health

                                        2

<PAGE>

                                                                       SECTION 1
                                                            AMENDED JUNE 2, 2004

SECTION 1. DESIGNATION AS PRIMARY WHOLESALER.

(a) Retail Pharmacies. During the term of this Agreement, CVS will designate
Cardinal as the primary wholesale pharmaceutical supplier to designated
pharmacies operated by CVS (collectively, the "PHARMACIES" and individually, a
"PHARMACY") subject to Section 1(a) Disclosure Schedule. A list of the
Pharmacies (the "DESIGNATED PHARMACY LIST") will be provided by CVS to Cardinal
from time to time during the term of this Agreement.

(b) Distribution Centers. During the term of this Agreement, CVS will designate
Cardinal as the primary wholesale pharmaceutical supplier to all distribution
centers operated by CVS ("CVS PHARMACY DCS") subject to Section 1(b) Disclosure
Schedule. A comprehensive list of all of the CVS Pharmacy DCs as of January 1,
2004 (the date of this agreement) (the "TOTAL DC LIST") is set forth in the
Section 1(b) Disclosure Schedule.

(c) CVS PharmaCare. This Agreement specifically excludes purchases which are
made by CVS on behalf of the CVS division known as PharmaCare with the following
one exception: In return for an [***]% ([***] % [***]%) [***] the [***] as
described in the Section 12 Disclosure Schedule, CVS will service the [***] and
[***] facilities that were acquired from JC Penney and operated by PharmaCare
("[***] FACILITIES") from a CVS Pharmacy DC being serviced by Cardinal for a
period of [***] ("FIRST TERM"). If at anytime after the First Term, CVS
discontinues servicing said [***] Facilities from a CVS Pharmacy DC being
serviced by Cardinal, then the [***] as described in the Section 12 Disclosure
Schedule will [***]% [***]%. If CVS continues servicing said [***] Facilities
from a CVS Pharmacy DC being serviced by Cardinal after the First Term, then the
[***] as described in the Section 12 Disclosure Schedule will [***] at [***]%
for as long as CVS continues servicing said [***] from a CVS Pharmacy DC being
serviced by Cardinal.

This Agreement specifically excludes any secondary, drop ships, direct, or
direct-store-delivery purchases made by PharmaCare on behalf of the Mail-order
Facilities.

As it concerns the Mail-order Facilities only, in the event either party desires
not to continue to service the Mail-order Facilities from a CVS Pharmacy DC
being serviced by Cardinal at the expiration of the First Term or any renewal
term, that party shall provide the other party with at least [***] ([***]) days
written notice prior to the expiration of the then current term. In the event
such notification is not provided with at least the [***] ([***]) day notice or
if no notice is given, the then current term shall be extended for a period of
[***] ([***]) days after the expiration of such term to provide for an adequate
transition period.

(d) CVS Commitment. This Agreement pertains only to CVS' Pharmacies and CVS
Pharmacy DCs as of January 1, 2004 plus or minus the organic growth related to
Pharmacies.

                                        3

<PAGE>

                                                  SECTION 12 DISCLOSURE SCHEDULE
                                                            AMENDED JUNE 2, 2004

                           WAREHOUSE LOGISTICS PROGRAM

The goal of the "WAREHOUSE LOGISTICS PROGRAM" (WLP") is to develop the most
efficient purchasing and distribution processes for CVS with pharmaceutical
manufacturers under which Cardinal will [***] ([***]%) of CVS' purchase
requirements for [***] Rx Products (excluding repack items) ("[***]") [***] of
all CVS [***] which are or become part of this Agreement. The parties agree and
acknowledge that this WLP is part of this Agreement, and is not a separate or
distinct agreement.

Notwithstanding anything in this Agreement to the contrary, the WLP is intended
and structured to provide [***]% incremental financial and operational value to
CVS and at no time shall Cardinal take any action in connection with the WLP
which may negatively impact CVS' ability to service its Pharmacies, CVS Pharmacy
DCs, or CVS' abilities to secure regular [***] merchandise, including [***]
stock, [***] a manufacturer.

The WLP is designed to provide incremental financial value to CVS; CVS is to be
[***] on [***], etc. CVS will [***] all other [***] that CVS would otherwise be
entitled to if CVS [***] the [***] on a [***] (i.e., [***], etc.).

As part of the WLP, Cardinal will pass to CVS funding ("INCENTIVE") in the form
of a credit within [***] ([***]) days of the end of each CVS [***] equal to
[***]% times CVS Pharmacy [***] (in addition to passing the [***]) for the
respective CVS fiscal quarter during the term of this Agreement. The credit will
be faxed and subsequently mailed in hard copy form to CVS' Manager of Wholesaler
Programs. Additionally, Cardinal will provide CVS with the Warehoused Service
Level detailed in Section 2(b) Disclosure Schedule through leveraging Cardinal's
procurement and logistical expertise. In return for both the Incentive and the
Warehouse Service Level, Cardinal will [***] the [***] created through certain
"[***] CREATION ACTIVITIES" as defined below.

Current [***] will remain in place as of the execution of this Agreement with
the exception of [***], which will [***] from a CVS [***] to an [***] (as
detailed in and subject to Section 12 Disclosure Schedule) . Cardinal will [***]
as it does for any other indirect vendor. In return for [***] on an [***] from
February 1, 2004 until December 31, 2004, by May 1, 2004, Cardinal will
authorize CVS to [***] in the amount of $[***] ("[***] PAYMENT"). The timing of
said payment will be made so that CVS receives these funds by [***].

CVS will not be required to [***] or [***] any other pharmaceutical [***] as a
[***]. Any further [***] of pharmaceutical [***] from [***], will be at CVS'
sole determination. The [***] Warehouse [***] Exhibit below details which [***]
CVS will purchase from Cardinal on an indirect basis (subject to Section 12
Disclosure Schedule) and the corresponding [***] terms to be amended in writing
pursuant to Section 13 upon mutual agreement of CVS and Cardinal. While CVS and
Cardinal may both agree that it is in the best interest of both parties to [***]
a [***] from [***] to [***] or visa versa, said decisions will always be made to
reflect incremental value to CVS and will occur at CVS' sole discretion.

                                        4

<PAGE>

CVS is under no obligation to purchase any specific [***] and may eliminate
(POX) or discontinue any item at its sole discretion. With that said, CVS and
Cardinal may investigate the best methods of [***] any [***] inventory [***] at
CVS' sole discretion. So that Cardinal and CVS can effectively and efficiently
manage Cardinal's [***] that is [***] to CVS through the [***], Cardinal will
provide to CVS in an electronic format a detailed weekly report detailing said
[***] ("[***] REPORT"). The [***] Report will include but not be limited to the
following elements as it pertains to Cardinal [***] to CVS: [***], description,
NDC, [***] on hand, extended [***], and [***] date. As it pertains to populating
the [***] date [***] of the [***] Report only, Cardinal will fully populate and
update [***] on a monthly basis and will supply to CVS a fully updated [***]
Report by the first Friday following Cardinal's commencement of recording said
[***]. All other data elements will be updated weekly and immediately sent to
CVS each Friday accurately representing Cardinal's [***] available to CVS as of
the creation of the [***] Report.

[***] CALCULATION.

For all of CVS Pharmacy DCs [***] ([***], or Brokerage Purchases, etc), CVS will
receive an [***] within [***] ([***]) days of the end of each CVS fiscal quarter
in the form of a [***] equal to [***]% times CVS Pharmacy DCs [***] (in addition
to [***] the [***]) for the respective CVS fiscal quarter during the term of
this Agreement. The [***] will be calculated based on CVS' receipt date of such
[***] for each fiscal month. CVS and Cardinal will agree with the method used to
calculate each month's [***] totals.

For example; CVS' total [***] volume for a specific CVS fiscal quarter equals
$[***], then Cardinal will [***] to CVS within [***] ([***]) days of the end of
the respective fiscal quarter $[***] ($[***] x [***]).

Further terms and conditions of the [***] calculation are as follows:

     1)   CVS and Cardinal will publish the agreed to monthly [***] volume
          eligible for the [***] on a monthly basis; within [***] ([***]) days
          of the respective CVS fiscal month's end or as soon as practical.

     2)   The [***] will not be applied on [***] or [***] volume that is [***].
          The [***] will be automatically applied on this inventory when [***]
          as a [***].

     3)   CVS contract pricing on select [***] items established by CVS after
          January 1, 2004 will not be eligible for the [***] since Cardinal does
          not have the ability to [***] from this applicable [***].

     4)   The [***] is based on the assumption that Cardinal will not [***] CVS
          any [***] related to [***] on code [***] and code [***] purchase
          orders.

     5)   Cardinal will not apply the [***] on CVS [***] or [***] that was
          specifically [***] through CVS that Cardinal [***] CVS with the
          explicit purpose of this product being

                                        5

<PAGE>

     [***] the manufacturer. However, Cardinal will [***] on any [***] CVS [***]
     said product to the respective manufacturer.

          a.   This inventory will be [***] to CVS on the earliest date that the
               applicable manufacturer would accept said product [***] at [***]
               percent ([***]%).

          b.   If CVS believes the [***] to be [***] and that it will be [***]
               in any way by [***] said product [***] a manufacturer, then CVS
               can at its sole discretion opt not to [***] in such a [***].

          c.   CVS and Cardinal agree that [***] are costly to both parties and
               lead to operational inefficiencies and will therefore work
               together to develop a process which limits the amount of [***] .

     6)   At the start of this Agreement, Cardinal will [***] related to the
          previous agreement. To that end, CVS and Cardinal have agreed that
          Cardinal will adjust CVS' 4Q 2003 [***] by $[***] in order for this
          [***] to qualify for the [***]. With this adjustment made, [***] of
          CVS' [***] will be eligible for the [***] under this Agreement.

     7)   The calculation of the [***] will be based off the [***] ([***] at the
          [***] of [***] or the [***]) [***] to the application of the cash
          discount. For example, if the [***] is $[***], then the [***] would be
          calculated based on the $[***], not the $[***] ([***]% cash discount
          is applied).

     8)   For all CVS warehouse purchases made through Cardinal, cash discount
          [***] to CVS is defined as the [***].

     9)   If CVS [***] a [***] from [***] to [***] after the establishment of
          the [***] and [***], then Cardinal will [***] the [***] calculation on
          that affected volume.

     10)  If CVS enters into an [***] (as defined below) with a [***] that
          prohibits Cardinal from any [***] with this [***], then Cardinal will
          not apply the [***] calculation on that affected volume.

[***] CREATION ACTIVITIES.

As a function of the WLP, Cardinal will [***] the margin created through certain
[***] Creation Activities as defined below. Through the WLP, Cardinal will
[***]% of the margin associated with all [***] related to [***] detailed below,
and [***] related to [***] (this [***] was [***] to CVS via [***]) as further
defined below. Notwithstanding anything else in this Agreement to the contrary,
Cardinal will not place [***] purchases or conduct [***] activities related to
CVS [***] for which Cardinal has entered into an [***] such activities.

The "[***] CREATION OPPORTUNITIES" for the WLP are limited to:

     a)   [***] - all purchases of [***] Rx Products (excluding repack) designed
          to generate an [***] which result from the [***] (by way of
          illustration only and not as a limitation, one example of an [***] is
          [***] of a [***]).

                                        6

<PAGE>

     b)   [***] or [***] - [***] or [***] that are made available to Cardinal
          from [***] under which Cardinal [***] related to CVS' [***].

     c)   [***] - all purchases of [***] Rx Products (excluding repack) for a
          specified [***] of [***] offered by manufacturers [***], or [***], a
          [***], thereby [***]. (by way of illustration only and not as a
          limitation, one example of an [***] is where a vendor [***] at a [***]
          for a certain [***] Rx Product (excluding repack) [***]). This [***]
          was [***] to CVS via [***].

Further terms and conditions of the [***] Creation Activities are as follows:

1)   CVS will [***] other historically [***] ([***] and [***]manufacturers); CVS
     will not be required to [***] to Cardinal.

2)   CVS to [***] all [***] it has historically [***] to include but not limited
     to:

     a)   [***]

     b)   [***]

     c)   [***]

     d)   [***]

3)   The [***] CVS receives based on CVS' [***] purchases, is [***]% by CVS. In
     the event that a [***] would begin to [***] "[***]" [***] to Cardinal,
     Cardinal would [***]% of this [***] to CVS, based on CVS purchases
     (Pharmacies and CVS Pharmacy DCs, if applicable). Notwithstanding the
     foregoing, Cardinal will not accept any other [***] on CVS' behalf relating
     to CVS' purchase [***] (warehouse or DSD) without CVS' expressed written
     consent. It will be Cardinal's sole responsibility to notify any
     pharmaceutical supplier in writing (with copy to CVS subject to Section 13)
     [***] a [***] to Cardinal related to CVS' [***] of CVS' Return Goods
     Policy.

4)   CVS will only accept product shipped from Cardinal Brokerage Inventory to
     CVS Pharmacy DCs that has at least [***] ([***]) [***] remaining. All
     products shipped with less than [***] ([***]) [***] remaining will be
     considered "[***] PRODUCT". On an exception basis, CVS will allow Cardinal
     to ship [***] Product Brokerage Inventory with at least [***] ([***])
     months [***] remaining. However, both parties agree that no more than
     $[***] worth of [***] Product will be shipped to CVS Pharmacy DCs during
     any Program Year. In addition, upon CVS request (as often as monthly),
     Cardinal will provide CVS a detailed report that summarizes all [***]
     Product shipped from Cardinal's Brokerage Inventory to CVS Pharmacy DCs
     ("[***] REPORT"). The [***] Report will contain all [***] Product shipped
     to CVS Pharmacy DCs within the current Program Year and will include but
     not be limited to the following data elements: date shipped, vendor,
     description, NDC, quantity shipped, extended cost, and [***] totaled by
     month and year-to-date(both CVS and Cardinal agree that the [***] Report
     will be made available to CVS no later than September 1, 2004).
     Notwithstanding anything in this Agreement to the contrary, at no time will
     Cardinal ship Brokerage Inventory with less than [***] ([***]) months [***]
     remaining to CVS Pharmacy DCs. With that said, CVS will work with Cardinal
     to assist in the management of the [***].

                                        7

<PAGE>

Additional terms and conditions of the WLP are as follows:

1.   Term - The WLP will commence as of January 1, 2004, and terminate upon the
     termination of the Agreement.

2.   [***] Generation - Cardinal will [***] ([***]%) of CVS' [***] for [***] Rx
     Products (excluding repack) [***] all CVS Pharmacy DCs for routine [***]
     and [***] (the "PURCHASING ACTIVITIES").

3.   [***] - If Cardinal's [***] on CVS' [***] are [***] or [***] by a [***],
     and if CVS is eligible to [***] from such [***], then CVS will, upon
     request by Cardinal, effect a direct [***] of the applicable Rx Product
     [***] by Cardinal. With respect to the foregoing purchases, [***] will
     [***] the applicable [***] according to the [***], including [***] for any
     available [***]. CVS will [***] the [***] to the [***] from [***] Cardinal,
     which will also be [***] the [***]. This [***] process is designed to be
     "[***]" for both parties.

     (a) [***]. On the same day as CVS [***] a shipment of Rx Product ordered as
     part of a [***] related to this WLP, CVS will [***] Cardinal. Cardinal will
     [***] such Rx Product [***] the applicable CVS [***], and [***] the
     applicable Cardinal [***]. CVS will [***] from the applicable [***], and
     CVS will pay the [***], [***] for all [***], based on the applicable
     payment terms. CVS will [***] to the [***] from [***], and Cardinal will
     [***] the CVS [***] to the applicable [***]. The process outlined in the
     Section 2(b) Disclosure Schedule will apply to any discrepancies.

     (b) [***] and [***]. As it pertains to [***]purchases only, on the same day
     as CVS [***] the shipment of Rx Product, CVS will [***] Cardinal. Cardinal
     will [***] to [***] such Rx Product [***] the applicable CVS [***], and
     [***] the applicable Cardinal [***]. [***] purchases will be [***] by
     Cardinal at the servicing Cardinal DC [***] the need for CVS to [***] such
     product.

     As it pertains to the payment of [***] and [***] purchases, Cardinal will
     receive an [***] from the applicable [***] for the ordered Rx Product, and
     Cardinal will [***] the [***] directly, [***] for all [***], based on the
     applicable payment terms. As the Rx Product is ordered from Cardinal by CVS
     for [***], Cardinal will [***] CVS, and CVS will [***] Cardinal for such Rx
     Product in accordance with the terms of this Agreement. The process
     outlined in the Section 2(b) Disclosure Schedule will apply to any
     discrepancies.

4.   Purchase Information - CVS will provide Cardinal with [***] electronic
     feeds updating information regarding CVS' [***] of [***] Rx Products [***]
     from [***] and from [***] on behalf of the CVS Pharmacy DCs pursuant to the
     WLP. Such information will include details regarding all purchase orders,
     [***] or [***] for items [***] and [***] and other information reasonably
     required by Cardinal to administer the WLP. To assist Cardinal with [***],
     CVS will provide Cardinal with information reasonably requested by Cardinal
     including but not limited to new product [***], [***] fluctuations, [***]
     promotions, and new store openings , and a change in CVS Pharmacy DC that
     services a particular Pharmacy.

                                        8

<PAGE>

5.   Limitations - All [***] for [***] Products must be executed exactly as
     [***]. [***] will be generated and submitted to any vendor, other than
     those [***], without [***]. All [***] will be on behalf of the CVS Pharmacy
     DCs. CVS will not make any [***] (outside of this [***]) on behalf of the
     Pharmacies [***]. It is understood and agreed that Cardinal will not be
     required to reduce or otherwise [***] its own [***] associated with a
     manufacturer imposed [***]. Furthermore, the parties acknowledge and agree
     that all information associated with the WLP is confidential information
     subject to the provisions of Section 17 of this Agreement.

6.   Records, Audit and Confidentiality - The WLP is subject to the record
     keeping and audit provisions set forth in Section 16 of this Agreement.
     Cardinal may disclose CVS' [***] information (such as inventory [***],
     on-order or [***]) to [***] as reasonably required by Cardinal to [***]
     related to the WLP. Cardinal will notify CVS in writing (subject to Section
     13) prior to the disclosure of any such information and will provide the
     nature of the information that Cardinal intends to disclose. Further,
     Cardinal will use reasonable efforts to obtain applicable [***] consent to
     disclose such information to CVS if needed.

7.   ACH - All payments for invoicing under the WLP will be made via ACH.

8.   Waiver - Neither party's failure to enforce any provision of this WLP will
     be considered a waiver of any future right to enforce such provision.

9.   Dispute Resolution Relating to the WLP - CVS and Cardinal acknowledge that
     either party may from time to time may, in good faith, dispute any portion
     of the WLP. In the event that either party disputes any portion on the WLP,
     each party agrees to use all reasonable efforts to resolve all such
     disputes as expeditiously as possible on a fair and equitable basis. To
     that end, Cardinal and CVS will assemble a panel consisting of at least one
     (1) executive from CVS and one (1) executive from Cardinal (but in any
     event, an even number in the aggregate) (the "EXECUTIVE COMMITTEE") to
     resolve disputes relating to the WLP and address other issues as they may
     determine. With respect to reporting disputes, a copy of the terms of this
     Agreement, as amended from time to time, agreed upon facts and areas of
     disagreement, and a concise summary of the basis for each side's
     contentions will be provided to the executives who will review the same,
     confer, and attempt to reach a mutual resolution of the issue within thirty
     (30) days following either party's receipt of notice of dispute.

[***] VENDOR EXHIBIT.

<TABLE>
<CAPTION>
[***] VENDOR   [***] PURCHASE PAYMENT TERMS
------------   ----------------------------
<S>            <C>
[***]                      [***]
</TABLE>

                                        9<PAGE>
                                                                   EXHIBIT 10.06

[***] indicates the omission of confidential portions for which confidential
treatment has been requested. Such confidential information has been filed
separately with the Securities and Exchange Commission.

                               SECOND AMENDMENT TO
                             PRIME VENDOR AGREEMENT

          THIS SECOND AMENDMENT TO PRIME VENDOR AGREEMENT ("SECOND AMENDMENT")
is among Cardinal Health*, formerly known as Cardinal Distribution,
("CARDINAL"), and Express Scripts, Inc. ("BUYER").

          WHEREAS, Cardinal and Buyer executed a Prime Vendor Agreement, dated
July 1, 2001 (the "AGREEMENT"), and executed a First Amendment to Prime Vendor
Agreement, dated January ___, 2003 ("FIRST AMENDMENT").

          WHEREAS, the parties desire to further amend the Agreement, as
amended, to reflect the terms of a new returned goods policy for unmerchantable
product.

          NOW THEREFORE, in consideration of the foregoing recitals, the parties
hereby agree as follows:

     1. RETURNED GOODS POLICY FOR UNMERCHANTABLE PRODUCT. Attached as EXHIBIT A
and incorporated herein by reference is a returned goods policy for
unmerchantable product, which describes a return process whereby Cardinal will
assist Buyer in receiving value for certain unmerchantable product.

     2. MISCELLANEOUS. Capitalized terms not defined herein will have the same
meaning ascribed to them in the Agreement, as amended by the First Amendment, it
being the intent of the parties that the Agreement, as amended by the First
Amendment, and this Second Amendment will be applied and construed as a single
instrument. The Agreement, as amended by the First Amendment and as modified by
this Second Amendment, constitutes the entire agreement between Cardinal and
Buyer regarding the subject matter of the Agreement, as amended by the First
Amendment, and this Second Amendment and supersedes all prior or contemporaneous
writings and understandings between the parties regarding the same. This Second
Amendment will be binding upon the parties, their heirs, legal representatives,
successors and assigns. The terms and provisions of this Second Amendment are
severable. If any term or provision of this Second Amendment is determined to be
illegal or unenforceable by a court of competent jurisdiction, the remaining
terms and provisions of this Second Amendment and the Agreement, as amended by
the First Amendment will remain in full force and effect. This Second Amendment
may only be amended in a writing signed by Cardinal and Buyer.

     3. EFFECTIVE DATE. This Second Amendment shall be effective as of the date
of full execution ("EFFECTIVE DATE"). Except as otherwise amended herein, the
terms and conditions of the Restated Agreement shall remain in full force and
effect.

CARDINAL HEALTH*                        EXPRESS SCRIPTS, INC.

By: /s/ John E. Grimm                   By: /s/ George Paz
    ---------------------------------       ------------------------------------
Name: John E. Grimm                     Name: George Paz
Title: SVP, Alternate Care              Title: President
Date: 11-19-03                          Date: 11/12/03

*    The term "CARDINAL HEALTH" means the following pharmaceutical distribution
     companies including: Cardinal Health 106, Inc. (formerly known as James W.
     Daly, Inc.), a Massachusetts corporation (Peabody, Massachusetts); Cardinal
     Health 103, Inc. (formerly known as Cardinal Southeast, Inc.), a
     Mississippi corporation (Madison, Mississippi); Cardinal Health 110, Inc.
     (formerly known as Whitmire Distribution Corporation), a Delaware
     corporation (Folsom, California) and any other subsidiary of Cardinal
     Health, Inc., an Ohio corporation ("CHI"), as may be designated by CHI.

<PAGE>

                                    EXHIBIT A

                RETURNED GOODS POLICY FOR UNMERCHANTABLE PRODUCT

Cardinal and Buyer have agreed to pursue a return process whereby Cardinal will
assist Buyer in receiving value for certain unmerchantable Product. Product
which may not be returned pursuant to Cardinal's Standard Returned Goods Policy
may be returned to an authorized manufacturer through a third party pursuant to
this policy. Products which are "UNMERCHANTABLE" include, but are not limited
to, those items which Cardinal determines are not in "merchantable condition"
(as defined in Cardinal's Returned Goods Policy), and the following:

A. Any item which has been used or opened, is a partial dispensing unit or unit
of sale, is without all original packaging, labeling, inserts or operating
manuals, or that is stickered, marked, damaged, defaced or otherwise cannot
readily be resold by Cardinal for any reason.

B. Short-dated (less than seven (7) months expiration dating), outdated, or
seasonal product and items purchased on a "special order" basis, including
non-stock and drop ship items.

C. Any sterile or refrigerated Merchandise, unless Cardinal is specially assured
that such Merchandise was properly stored and protected at all times and such
Merchandise is returned separately in a package marked as such and accompanied
by a separate credit request form.

D. Any low stability product, including Epogen(TM), Eminase(TM), or other
products which are usually sensitive to temperature and handling conditions.

E. Any product not intended for return to a wholesaler in accordance with the
return policies of the applicable manufacturer.

Product in "unmerchantable condition" may generally be returned to vendors (a)
with which Cardinal has a current relationship, (b) are not either insolvent or
subject to a petition in bankruptcy, or (c) which do not have an outstanding
balance due Cardinal at the date on which such Product is submitted for return
(each such vendor, an "ACTIVE MANUFACTURER"). Unmerchantable Product may only be
returned through a third party return processor ("THIRD PARTY") in accordance
with the terms and conditions described in this policy. Cardinal will provide
the Third Party selected by Buyer with a current list of all Active
Manufacturers. Any Third Party selected by Buyer must enter into a
Confidentiality Agreement, in a form acceptable to Cardinal, prior to accepting
any returns from Buyer.

                             PROCEDURES FOR RETURNS

Buyer and Cardinal will notify each Active Manufacturer of their relationship as
customer/wholesaler. Buyer will send all returns of unmerchantable Product to
its selected Third Party. The amount identified by the Third Party as the amount
to which Buyer is entitled in exchange for the return will be determined in
accordance with the return policy of the applicable Active Manufacturer as
described in the Third Party's database, which will reflect Buyer's cost of
goods purchased through Cardinal. Buyer will instruct the Third Party to provide
Cardinal with documentation (either in paper or electronic format) to
substantiate each debit memo submitted to Active Manufacturers on behalf of
Buyer.

Buyer will instruct each Active Manufacturer to issue any and all credits to
Cardinal for Merchandise that was purchased by Buyer from Cardinal and is
returned through a Third Party in unmerchantable condition, and to reference the
debit memo number corresponding to the debit memo prepared by the Third Party.
Buyer and Cardinal acknowledge that Buyer will handle, without Cardinal's
involvement, all matters relating to returns to manufacturers with which Buyer
has a direct contracting relationship (whether or not such manufacturer is an
Active Manufacturer).

Buyer will pay the Third Party directly for all of such Third Party's fees. In
addition, Buyer will reimburse Cardinal for all costs billed by the Third Party
to Cardinal that relate to Buyer's returns hereunder, including, but not limited
to, processing fees, postage, delivery and destruction fees.

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<PAGE>

Cardinal will be paid [***]% of the net returns received by Cardinal from all
Active Manufacturers as a processing fee (the "PROCESSING FEE") in accordance
with the following procedure:

          (1) Cardinal will adjust Buyer's account upon the earlier of receipt
of an actual credit from an Active Manufacturer, or within sixty (60) days
following the date of a debit memo submitted to an Active Manufacturer. Buyer
will not deduct from any UNAUTHORIZED amounts owed to Cardinal, any UNAUTHORIZED
amounts relating to the return of Merchandise through a Third Party.

          (2) Each calendar month, Cardinal will (a) track credits due Buyer'S
account in the amount received by Cardinal from each Active Manufacturer during
such month for Buyer returns (or, if not received within sixty (60) days, the
amount anticipated to be received as shown on the debit memo), and (b) adjust
previously made credits to Buyer's account to reflect actual credits authorized
to Cardinal for returned Product, so that a net credit may be determined.

          (3) Within five (5) business days after the end of the previous
calendar month, Cardinal will credit Buyer's account with the net amount due
Buyer for all Third Party Returns activities during the previous month, less the
Processing Fee.

With the monthly credit, Cardinal will provide Buyer with a report of all Active
Manufacturer credits and debit memos posted during such month. Cardinal will not
perform a detail line reconciliation of the amounts authorized by Active
Manufacturers as compared to the original debit memo.

Notwithstanding the foregoing, if the applicable Active Manufacturer (a) is in a
debit balance in Cardinal's accounts payable system, or (b) is subject to a
petition in bankruptcy or is deemed insolvent, then no credit will be issued to
Buyer, and the credit will accrue to Cardinal's benefit, until such time as the
Active Manufacturer is no longer in a debit balance, bankruptcy proceeding or
insolvent. In addition, the Third Party will be exclusively responsible for
resolving discrepancies relating to returned Product through such Third Party.

To the extent that Buyer desires to return Product to a supplier which is not an
approved Active Manufacturer, Cardinal will credit Buyer's account only after
Cardinal receives payment either through check, money order or wire transfer. If
check, wire transfer or any other payment method is employed which does not
guarantee Cardinal immediately available funds, Cardinal will credit Buyer's
account only upon receiving such funds in Cardinal's account. Buyer may not
offset payments due from Buyer to Cardinal for Product purchases against any
amounts Buyer deems are due and owing pursuant to this Third Party Returned
Goods Policy.

Cardinal may modify this Third Party Returned Goods Policy in its reasonable
discretion from time to time. The Buyer is to be notified within thirty (30)
days of a modification and such modification is subject to mutual agreement.

                                       3

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