Document:

EX-10.1

 Exhibit 10.1 

FIRST AMENDMENT 
 TO

 AMENDED AND RESTATED LOAN AND SECURITY AGREEMENT 

THIS FIRST AMENDMENT TO AMENDED AND
RESTATED LOAN AND SECURITY AGREEMENT (this “Amendment”) is entered into as of January 23, 2015, by and between HERCULES TECHNOLOGY
III, L.P. (“Lender”) and BIND THERAPEUTICS, INC. (“Borrower”). 
 RECITALS 

Borrower and Lender are parties to that certain Amended and Restated Loan and Security Agreement dated as of June 12, 2013 (as amended
from time to time prior to the date hereof, the “Agreement”). As of the First Amendment Date, Borrower owes Lender a principal amount of $3,132,554.05 (the “Existing Loan 2”). Borrower has requested a term loan to
refinance Existing Loan 2 and for general corporate purposes, and Lender has agreed to make that loan to Borrower, on the terms set forth in this Amendment. Unless otherwise defined herein, capitalized terms in this Amendment shall have the meanings
assigned in the Agreement. 
 NOW, THEREFORE, the parties agree as follows: 

1. The following terms and definitions in the Agreement are amended or added to Section 1.1, as follows: 

“Advance” means the Term Loan. 

“Existing Loan 2” has the meaning given to it in the First Amendment. 

“First Amendment” means the First Amendment to Amended and Restated Loan and Security Agreement, by and between Lender and Borrower.

 “First Amendment Date” means January 23, 2015. 

“Interest Only Period” means the period from the First Amendment Date through December 31, 2015. 

“Interest Rate” means a floating per annum rate equal to (a) 8.35% plus (b) the Prime Rate minus 3.25%, not in any case
less than 8.35% per annum. 
 “Maturity Date” means July 2, 2018. 

“Term Loan” means the Advance made under Section 2.1(a). 

“Warrant” means the Warrant Agreement, dated as of the First Amendment Date, by Borrower in favor of Lender. 

2. Section 2.1 is amended and restated to read in its entirety as follows: 

2.1 Term Loan. 

(a) Advance. Subject to the terms and conditions of this Agreement, on the First Amendment Date, Lender shall make the
Term Loan to Borrower in an aggregate principal amount of $15,000,000. Borrower shall use the first proceeds of the Term Loan to repay the Existing Loan 2 in full and any remaining proceeds of the Term Loan for general corporate purposes.
Lender’s commitment to make the Term Loan is Lender’s sole commitment to extend credit to Borrower, and from and after the First Amendment Date, Lender shall have no commitment to make any other Advances under the Agreement. 

 (b) Advance Request. To obtain the Term Loan, Borrower shall complete,
sign and deliver an Advance Request to Lender. Lender shall fund the Term Loan in the manner requested by the Advance Request. 

(c) Interest. The principal balance of the Term Loan shall bear interest thereon from such Advance Date at the Interest
Rate based on a year consisting of 360 days, with interest computed daily based on the actual number of days elapsed. The Interest Rate will float and change on the day the Prime Rate changes from time to time. 

(d) Payment. During the Interest Only Period, Borrower will pay interest on the Term Loan on the first business day of
each month, beginning the month after the Advance Date. Borrower shall repay the aggregate Term Loan principal balance that is outstanding on the date the Interest Only Period expires in equal monthly installments of principal and interest (mortgage
style) beginning the first business day of the month after the expiration of the Interest Only Period and continuing on the first business day of each month thereafter. The entire Term Loan principal balance and all accrued but unpaid interest
hereunder, shall be due and payable on Maturity Date. Borrower shall make all payments under this Agreement without setoff, recoupment or deduction and regardless of any counterclaim or defense. Lender will initiate debit entries to Borrower’s
account as authorized on the ACH Authorization on each payment date of all periodic obligations payable to Lender under the Term Loan. 

3. Section 2.4 is amended and restated to read in its entirety as follows: 

Prepayment. At its option upon at least 5 business days prior notice to Lender, Borrower may prepay any part of the outstanding Term
Loan by paying the principal balance, all accrued and unpaid interest, together with a prepayment charge (the “Prepayment Charge”) equal to 3.0% of the amount being prepaid if prepaid before the first anniversary of the First Amendment
Date, 2.0% of such amount if prepaid after the first but before the second anniversary of the First Amendment Date, and 1.0% of such amount if prepaid on or after the second anniversary of the First Amendment Date. Borrower shall pay the Prepayment
Charge upon any prepayment of the Secured Obligations arising out of the occurrence of an Event of Default. Borrower agrees that the Prepayment Charge is a reasonable calculation of Lender’s lost profits in view of the difficulties and
impracticality of determining actual damages resulting from an early repayment of the Term Loan. 
 4. Section 2.5 is amended
and restated to read in its entirety as follows: 
 End of Term Charge. Borrower shall pay Lender the charge of $165,750 in connection
with the Existing Loan 2 (the “End of Term Charge”) specified in Section 2.5(b) of the Agreement on the earliest to occur of (i) September 1, 2016, (ii) the date that Borrower prepays the outstanding Secured Obligations
(other than any inchoate indemnity obligations) in full, and (iii) the due and proper acceleration of the Secured Obligations by Lender. In addition, on the earliest to occur of (i) the Maturity Date, (ii) the date that Borrower
prepays the outstanding Secured Obligations (other than any inchoate indemnity obligations) in full, or (iii) the due and proper acceleration of the Secured Obligations by Lender, Borrower shall pay Lender a charge equal to $750,000 (the
“Second End of Term Charge”). Notwithstanding the required payment date of such charge, the End of Term Charge is deemed earned by Lender as of the Closing Date, and the Second End of Term Charge incurred in connection with this Amendment
is deemed earned by Lender as of the First Amendment Date. 
 5. As security for the prompt and complete payment when due (whether on
the payment dates or otherwise) of all the Secured Obligations, Borrower hereby reaffirms its grant and grants to Lender a security interest in Collateral. 

6. Lender waives any prepayment fee due to Lender pursuant to Section 2.4 of the Agreement (as in effect prior to this Amendment)
due to the prepayment of Existing Loan 2. 

 7. The Agreement, as amended hereby, shall remain in full force and effect in accordance
with its terms. Except as expressly set forth herein, the execution, delivery, and performance of this Amendment shall not operate as a waiver of, or as an amendment of, any right, power, or remedy of Lender under the Loan Documents, as in effect
prior to the date hereof. This Amendment shall constitute a Loan Document for purposes of the Agreement and from and after the First Amendment Date, all references to the Agreement in any Loan Document and all references in the Agreement to
“this Agreement”, “hereunder”, “hereof” or words of like import referring to the Agreement, shall, unless expressly provided otherwise, refer to the Agreement as amended by this Amendment. 

8. This Amendment may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together
shall constitute one instrument. 
 9. As a condition to the effectiveness of this Amendment, Lender shall have received, in form and
substance satisfactory to Lender, the following: 
 (a) this Amendment, duly executed by Borrower; 

(b) payment of (i) a non-renewable facility charge of $150,000 and (ii) an amount equal to the Lender Expenses incurred in
connection with this Amendment; 
 (c) a certificate of an officer of Borrower; 

(d) an Advance Request, duly executed by Borrower; and 

(e) the Warrant. 
 10.
This Agreement shall be governed by, and construed and enforced in accordance with, the laws of the State of California, excluding conflict of laws principles that would cause the application of laws of any other jurisdiction. 

11. Existing Loan 2 Refinanced. For the avoidance of doubt, the Existing Loan 2 set forth in the second sentence of Section 2.1(a)
of the Loan Agreement in effect prior to this Amendment has been terminated in full and is now replaced by the $15,000,000 Term Loan commitment set forth in this Amendment. 

 IN WITNESS WHEREOF, the
undersigned have executed this Amendment as of the first date above written. 
  

			
	BIND THERAPEUTICS, INC.
		
	By:	 	 /s/ Andrew Hirsch

		
	Title:	 	 Chief Operating Officer, Chief Financial Officer and Secretary

	
	HERCULES TECHNOLOGY III, L.P.
		
	By:	 	Hercules Technology SBIC Management, LLC, its general partner
		
	By:	 	Hercules Technology Growth Capital, Inc., its Manager
		
	By:	 	 /s/ Ben Bang

		
	Title:	 	 Associate General CounselEX-10.1

 Exhibit 10.1 

ACCEPTANCE AND RELEASE 

I have been informed that my employment with Layne Christensen Company (“Company”) has been terminated. I understand that I have
been offered a severance and benefit continuation program by the Company. 
 In consideration of the Company’s actions, I release and
forever discharge the Company, its subsidiaries and their agents, present and former directors, present and former officers, employees and representatives from any action, suit, contract, agreement, promise, liability, claim, demand, damage, loss,
cost or expense, of any nature whatsoever, known or unknown, fixed or contingent (hereinafter called “Claims”), which I now have or may hereafter have against them, by reason of any matter prior to and through the Effective Date (as
defined below), including, without limiting the generality of the foregoing, any Claims arising out of the hire, employment, remuneration (including any remuneration or payment under any bonus or incentive compensation plan) or termination of my
employment by the Company (including any Claims under Title VII of the Civil Rights Act of 1964, as amended; the Civil Rights Act of 1991; the Civil Rights Act of 1866, as amended; the Age Discrimination in Employment Act, as amended; the Americans
with Disabilities Act, as amended; the Equal Pay Act, as amended; the Fair Labor Standards Act, as amended; applicable state employment discrimination statutes; applicable state wage and hour statutes; and/or any other local, state or federal law
governing discrimination in employment and/or the payment of wages or benefits). 
 I understand that the severance program outlined in
Michael Caliel’s letter to me of January 23, 2015 (the “Letter”), will be effective immediately following my signing this Acceptance and Release, provided that I sign by 9 a.m. on January 23, 2015 (the “Effective
Date”). After this time, if this Release is not executed and returned, the severance program outlined in the Letter will cease to be of any force or effect. 

By my signature below, I acknowledge that (i) I have read and understand both the Letter outlining my severance program and this
Acceptance and Release and (ii) I agree to the terms and conditions set forth in both the Letter and this Release and will abide with their terms. 

Dated: January 23, 2015. 
  

	
	 /s/     Gernot E.
Penzhorn        

	Gernot E. Penzhorn

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