Document:

Acquisition Agreement regarding ECLIA technology dated as of January 18, 2005

 English translation: for reference only 
  
 Exhibit 10.4 
  
 Assets Acquisition Agreement 
  
 This “Assets Acquisition Agreement” (hereinafter referred to as “this Agreement”) is entered into on January 18, 2005 by and between the
following parties: 
  

			
	Party A:	  	Beijing Weixiao Biological Technology Development Company Limited (hereinafter referred to as “Weixiao”)
		
	Address:	  	No. 24, Yong Chang North Road, Beijing Economic-Technological Development Area, Beijing
		
	Party B:	  	Beijing Yuande Bio-Medical Engineering Company Limited (hereinafter referred as “Yuande”)
		
	Address:	  	No. 4, Zhong He Street, Beijing Economic and Technological Development Zone, Beijing

  
 WHEREAS: 
  

	1.	Weixiao is a limited liability company organized and exiting under the laws of the People’s Republic of China, with the qualification of an independent legal person, its main
business is technological development of biological products and sales of its self-made products. 

  

	2.	Yuande is a foreign investment limited liability company organized and existing under the laws of the PRC, with the qualification of independent legal person, its main business
includes technological development, service, manufacture and training of medical devices and biological medical engineering. 

  

	3.	Weixiao agrees, in accordance with the terms stipulated herein, to sell the relevant technologies and assets with respect to “chemiluminscence immunoassay diagnostics”
(hereinafter referred to as the “Subject Assets”, as defined below); Yuande agrees, in accordance with the terms stipulated herein, to purchase from Weixiao the Subject Assets and pay the corresponding consideration.

  
 NOW THEREFORE, in consideration of the foregoing premises, and
based on the mutual agreement and commitment as stipulated hereinafter, both parties agree as follows: 
  

					
	 	 	 	  	Article 1 Definitions
			
	1.1	 	Subject Assets	  	means the core technology of “chemiluminscence immunoassay diagnostics system” (hereinafter referred to as the “System”) and the assets related to the research and
development, testing, prototype equipment and relevant reagents in relation to the System legally owned by Weixiao. Up to the signing date of this Agreement, the medical device registration certificate and the reagent permit have already been
obtained.

					
	1.2	 	Core Technology	  	means the 27 reagent kits for clinical diagnostics that have already applied for registration or are going to apply for registration including the related technology, techniques,
technological information, technological data, intellectual property right of the reagent kits as listed in Appendix 1, patent as listed in Appendix 3 and technology and techniques of MPC-1 single-photon counting instrument. Core Technology is the
core components of the Subject Assets.
			
	1.3	 	Core Staff	  	means all key staff engaged in the research and development, testing and quality control of Core Technology, whose names are listed in Appendix 2.
			
	1.4	 	Assets Acquisition	  	means the purchase by Yuande of the Subject Assets owned by Weixiao in accordance with the terms and conditions as agreed in this Agreement.
			
	1.5	 	Appraisal Report	  	means the appraisal report on June 30, 2004 by an international qualified appraisal company, America Appraisal International Valuation Consultancy, retained by Yuande.
			
	 1.6    
	 	 Acquisition
 Consideration
	  	means the acquisition consideration as provided in Article 3 hereof to be paid by Yuande to Weixiao for purchasing the Subject Assets owned by Weixiao in accordance with the terms stipulated
in this Agreement.
			
	1.7	 	Acquisition	  	means the completion by Weixiao and Yuande of the transaction formalities for the transfer of the ownership of the Subject Assets.
			
	1.8	 	Acquisition Date	  	means July 9, 2004.
			
	1.9	 	Delivery Period	  	means the period beginning from July 9, 2004 to March 8, 2005.
			
	1.10	 	Encumbrance	  	means any security interest, pledge, mortgage, lien, lease, permit, indebtedness, priority arrangement, and limitation.
			
	1.11	 	Working Day	  	means any day other than Saturday, Sunday, and other date that commercial banks or the laws in China require to close for business.

  
 Article 2 Assets
Acquisition 
  

	2.1	In accordance with the terms hereof and subject to the satisfaction of the conditions precedent stipulated in Article 4 of this Agreement, Yuande agrees, in accordance with the
warranties and undertakings of Weixiao provided herein, to purchase the Subject Assets, and Weixiao agrees, as the legal owner of the Subject Assets, to sell the Subject Assets to Yuande. 

  

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	2.2	The original employment relationship of Weixiao’s Core Staff relating to the Subject Assets shall be terminated upon the delivery of the Subject Assets to Yuande. After Weixiao
terminates the employment relationship with the above-mentioned staff, Weixiao shall assist Yuande in discussing employment contract with the Core Staff. 

  

	2.3	The Subject Assets, at the time this Agreement is effective in accordance with Article 13, are legally wholly owned by Weixiao, and there is no Encumbrance to cause any limitation
or failure in realization of the validity and enforcement of this Agreement. 

  
 Article 3 Acquisition Consideration 
  

	3.1	Both parties, with referenced to the Appraisal Report issued by an international appraisal firm who has international appraisal qualification retained by Yuande and after
negotiations, mutually agree to this asset acquisition at a consideration of RMB250,000,000. 

  

	3.2	Payment time and method: 

  
 Prior to September 30, 2005, Yuande shall pay RMB250,000,000 to Weixiao. 
  
 Yuande shall make payment to Weixiao by check or bank draft. 
  
 Article 4 Conditions Precedent 
  

	4.1	In accordance with the provisions herein, Yuande’s final acceptance of the Subject Assets and its payment of the Acquisition Consideration is contingent on and is subject to
the following conditions precedent being satisfied prior to the deadline stipulated in Article 4.3 hereof: 

  

	 	(1)	Weixiao has obtained relevant permits including the medical device permit, reagent permit, medical device registration certificate, relating to the Subject Assets, especially
relating to the relevant permit of the Core Technology and such permits and approvals remain valid; 

  

	 	(2)	Weixiao undertakes to Yuande in respect of non-competition, and the form and contents of the undertaking are satisfactory and acceptable to Yuande; 

  

	 	(3)	Yuande has completed its due diligence of the Subject Assets (including but not limited to legal, financial and commercial aspects), and the results of the due diligence are
satisfactory and acceptable to Yuande; 

  

	 	(4)	Weixiao has obtained all necessary authorizations and approvals for carrying out the transactions hereunder; and 

  

	 	(5)	Prior to the completion of the Acquisition, Weixiao has not materially reached on any of the guaranties and undertakings stated herein. 

  

	4.2	In order to complete the due diligence investigation as mentioned in (3) above, Weixiao shall provide and/or procure others to provide to Yuande and/or its authorized persons all
relevant account books in relation to the assets and all the relevant information in relation to all the ownership certificates, etc. 

  

 3 

	4.3	Yuande may from time to time waive the conditions precedent of Article 4.1 in the form of writing. If any of the conditions precedent stated in Article 4.1 fails to be fully
achieved or be waived or exempted by Yuande before December 3l, 2004, or before a later date as agreed in writing by the parties, this Agreement shall immediately terminate and be deemed void. Except as otherwise provided in this Agreement, the
parties to this Agreement shall not undertake any liability and obligation in respect of this Agreement. However, the provision of this Article shall not affect any rights enjoyed by any party to this Agreement based on this Agreement in respect of
the other party’s reach of any terms hereof before the termination of this Agreement. 

  
 Article 5 Acquisition 
  

	5.1	Weixiao’s Delivery 

  
 Weixiao shall deliver or procure others to deliver to Yuande: 
  

	 	(1)	All information, ownership certificates, registration certificates, contracts, agreements, records and other relevant documents involving the Subject Assets;

  

	 	(2)	All permits and approvals involving the Core Technology; 

  

	 	(3)	All information related to the research and development, testing and market information of the Subject Assets, and documents evidencing Weixiao’s termination of its employment
relationship with the Core Staff; 

  

	 	(4)	The non-competition undertaking duly signed by Weixiao; 

  

	 	(5)	Resolutions passed by Weixiao’s shareholders meeting (or board of directors, as determined by their respective authority) approving the acquisition of the Subject Assets; and

  

	 	(6)	Other documents or books which are reasonably required by Yuande. 

  

	5.2	Yuande’s Delivery: 

  
 On or before the Acquisition, Yuande shall deliver to Weixiao: 
  

	 	(1)	Resolution passed by Yuande’s board of directors agreeing to purchase the assets in accordance with the terms of this Agreement. 

  

	5.3	Yuande and Weixiao hereby acknowledge that Weixiao has already delivered to Yuande all the documents stated in Articles 5.1(1), (2) and (3) on the Acquisition Date.

  

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	5.4	Failure to Complete 

  
 If any party to this Agreement (the “Breaching Party”) fails to comply with any stipulations as set forth in Article 5.1, Article 5.2 and
Article 5.3 due to any reasons, the other party may have the option to: 
  

	 	(1)	agree to continue to carry out the Acquisition; or 

  

	 	(2)	terminate this Agreement, and shall not be obliged to complete the transaction under this Agreement, and the Reaching Party shall indemnify the other party to this Agreement for all
economic losses reasonably incurred directly from such cause. 

  
 Provisions 5.4(1) and 5.4(2) shall not affect any other rights of the other party to this Agreement to claims for indemnification as provided by laws and this Agreement. 
  

	5.5	After the completion of Acquisition, the terms which have not been performed shall continue to be valid. 

  

	5.6	Beginning from the Acquisition Date, Weixiao shall stop all scientific research or activities relating to the Subject Assets and the Core Technology, including but not limited to
research and development, testing, prototype, market analysis, and publicity. The aforesaid activities and matters, from the Acquisition Date and during the Delivery Period or within a later time as agreed upon by the parties, shall be determined
and implemented solely at Yuande’s discretion. At the time when Yuande is engaged in the abovementioned activities, at Yuande’s request, Weixiao shall fully support, assist and cooperate. Beginning from the Acquisition Date, Yuande shall
undertake all rights and obligations related to the Subject Assets. Yuande shall complete all formalities for changes made under this Agreement, with Weixiao’s assistance. The Core Staff shall terminate their employment relationship with
Weixiao, and Weixiao shall assist Yuande in discussing employment contract with the Core Staff. 

  
 Article 6 Weixiao’s Representations, Warranties and Undertakings 
  

	6.1	Weixiao hereby warrants and undertakes to Yuande that the various warranties listed in Article 6.8 are complete and true (even after completion, the undertakings under this Article
shall continue to be in full force and effect), and confirms that the execution of this Agreement by Yuande is based on such warranties and deems such warranties as the conditions precedent to this Agreement. 

  

	6.2	Weixiao hereby warrants and undertakes to Yuande that it shall indemnify Yuande for all actual reasonable costs, expenditures, losses or other liabilities arising out of
Weixiao’s material breach of the warranties and undertakings stated in this Agreement. 

  

	6.3	Unless otherwise specified, every warranty listed in Article 6.8 is several and independent, and shall not be limited by any terms in this Agreement. 

  

	6.4	Before the Acquisition, Weixiao shall not act or permit to (expect as may be required for the implementation of this Agreement) act or omit to act which may cause the warranties to
be untrue or misleading in any material respect. 

  

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	6.5	Weixiao warrants to Yuande that all permits with respect to the Subject Assets (including the medical device permit, the medical device registration certificate, the reagent permit
and the patent certificate) remain valid before the completion of the Acquisition, and that Weixiao and other persons have not taken any actions, which may cause the cancellation or revocation of such permits (whether before or after the completion
of the Acquisition). 

  

	6.6	The rights and indemnifications enjoyed by Yuande in respect of the inaccuracy, untruthfulness or non-performance of Weixiao’s warranties shall not be affected by the
following: 

  

	 	(1)	Weixiao completes the acquisition of the assets to Yuande; or 

  

	 	(2)	Yuande completes its due diligence of the assets; or 

  

	 	(3)	Yuande has not exercised or delayed in exercising any rights or claims or delayed to make any indemnification claim. 

  

	6.7	Weixiao confirms and warrants that, the Subject Assets to be transferred to Yuande are not encumbered with any debt, any unsettled or foreseeable disputes, litigations,
arbitrations, administrative penalties, and any potential issues, external securities, all incurred or potential or contingent indebtedness such as any indebtedness infringing upon rights caused due to reasons of environmental protection,
intellectual property, product quality, labor safety, or personal right, etc. If Weixiao breachs in the above-mentioned warranties, it shall undertake the joint liabilities for the above-mentioned matters and be responsible for handling all issues
caused by the above-mentioned matters with respect to claims of third party rights, pay for all costs incurred, and be responsible for indemnifying Yuande against all economic losses thus caused. 

  

	6.8	In order to procure Yuande to sign this Agreement, Weixiao hereby represents and guarantees to Yuande as follows: 

  

	 	(1)	Weixiao’s Qualification 

  
 Weixiao is a company established and validly existing under PRC laws and it is a company with good standing. Weixiao has all necessary authorizations,
with the capacity to sign this Agreement, to perform its obligations hereunder, and to complete the assets acquisition as contemplated by this Agreement. This Agreement constitutes Weixiao’s legal, valid and binding obligations, which may be
implemented based on its terms, and may be enforced against Weixiao in accordance with the stipulations herein. 
  

	 	(2)	No Conflicts 

  
 Weixiao’s execution, delivery and performance of this Agreement does not and will not (a) violate or conflict with any provisions of Weixiao’s
Articles of Association (or similar constitutional documents), or lead to any breach under its Articles of Association (or similar constitutional documents), (b) violate or conflict with any laws and regulations applicable to the Subject Assets (or
cause any events of material adverse effect due to any laws and regulations), or (c) conflict with or lead to the violation of any mortgages, contracts, agreements, licenses, permits, franchise or other documents or arrangements, under which Weixiao
is a party or cause the Subject Assets to be subjected to or affected, or constitute any breach under such documents. 
  

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	 	(3)	Permits 

  
 The Subject Assets already includes all approvals, registrations, and authorization certificates related to the Core Technology. Weixiao has not violated in any important aspect such approvals, registrations or
provisions of other similar authorizations. All of such approvals, registrations and authorizations are still valid, have not expired, and have not been cancelled or terminated. Such approvals, registrations and authorizations will not be cancelled,
terminated or become invalid due to any transaction as agreed herein. Weixiao will endeavor its best efforts to assist Yuande to complete the formalities for modifying (or re-registering) all of such approvals, registrations and authorizations. The
execution and performance of this Agreement by Weixiao shall not require the permit or approval of any third party. 
  

	 	(4)	Patent 

  

	 	(a)	Patent related to the Subject Assets is the property right owned by Weixiao itself. The relevant registration for the change of ownership of the Subject Assets has already been
completed. 

  

	 	(b)	Except for the agreement as provided in item (a), Weixiao has not signed any patent, trade mark registration, registered design, copyright, technology, protected process or other
protected property or relevant agreements related to the Subject Assets. 

  

	 	(5)	Contracts 

  

	 	(a)	Except for what is disclosed in this Agreement, in respect of the Subject Assets, Weixiao has not provided any mortgage, security nor has issued any bonds (whether secured or not)
or any other security, nor has indemnified against the Subject Assets, nor has provided security to any individual or company with the Subject Assets. 

  

	 	(b)	There is no contractual arrangement or liability binding against the Subject Assets, which shall or may cause to terminate or breach caused by the validation of this Agreement or by
the completion of the transaction as agreed in this Agreement. 

  

	 	(c)	There is no gross negligence or material breach in any contract, undertaking, commitment or arrangement which is binding against Weixiao, which may cause the Subject Assets to be
mandatorily performed. To Weixiao’s knowledge, no such negligence or breach will incur or may incur as time passes by or due to receiving any notice or other reasons. 

  

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	 	(6)	Compliance with Law 

  
 Weixiao has always been engaged in and shall continue to be engaged in business in accordance with all laws and regulations applicable to Weixiao or the
Subject Assets before the Acquisition Date, and Weixiao has not violated any of such laws and regulations. 
  

	 	(7)	Complete Disclosure 

  

	 	(a)	To Weixiao’s knowledge, there are no facts related to the Subject Assets, which may result in a material adverse effect, and which has not been disclosed in this Agreement and
relevant appendixes, or Weixiao has not disclosed to Yuande in other forms of writing. 

  

	 	(b)	Weixiao’s representations or warranties in this Agreement, any documents, representations or certificates provided or to be provided by Weixiao as agreed in this Agreement or
related to the transaction as agreed herein do not currently include and will not in the future include any untruthful representation of material facts, and there is no omission currently and in the future that there will not be any omission of
material facts which may cause any such representations to be misleading. 

  
 Article 7 Yuande’s Representations, Warranties and Undertakings 
  

	7.1	In order to procure Weixiao to sign this Agreement, Yuande hereby warrants and undertakes to Weixiao as follows: 

  

	 	(1)	Yuande has the right to sign, deliver and perform this Agreement. 

  

	 	(2)	The execution of this Agreement shall constitute Yuande’s legal, valid and binding obligations, which may be implemented based on its terms, and may be enforced in accordance
with its terms against Yuande. Yuande’s execution and delivery of this Agreement, performance of its obligations under this Agreement and completion of the agreed transaction under this Agreement, has been duly authorized through the adoption
of all necessary actions. 

  

	 	(3)	Yuande’s execution and performance of this Agreement or exercise of its rights under this Agreement shall not (a) conflict with any laws, conditions and any other orders which
must be complied with; (b) conflict with any agreements and documents, to which Weixiao is a party; (c) conflict with the Articles of Association of Yuande; and (d) conflict with any agreements and documents binding against Yuande or its properties.

  
 Article 8 Obtaining of Information

  

	8.1	Beginning from the Acquisition Date, Weixiao will, in accordance with or procure others to follow, the reasonable request of Yuande to provide and arrange to Yuande and/or its
authorized persons to obtain all relevant books, all ownership certificates, records and accounts of the assets. 

  

	8.2	Yuande undertakes, except otherwise provided by law, prior to the Acquisition, Yuande will not disclose to any persons other than its senior officers or professional consultants any
information related to the assets obtained in accordance with this Agreement. 

  

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	8.3	Yuande undertakes, if this Agreement becomes void, all information and documents related to the assets given to Yuande in accordance with this Agreement must be returned to Weixiao.

  
 Article 9 Confidentiality 
  

	9.1	Both parties to this Agreement must keep strictly confidential the consultation of this Agreement, the process of execution and the content of this Agreement. Unless the laws,
regulations, or relevant governmental authorities have mandatory stipulations, it must not be disclosed to any third person. 

  

	9.2	Any party to this Agreement and its affiliates also have the obligation of to keep strictly confidential any commercial secrets of the other party to this Agreement known in the
process of consultations, execution and performance of this Agreement. Unless the laws, regulations, or relevant governmental authorities have mandatory stipulations, it must not be disclosed to any third person. 

  

	9.3	The above confidentiality obligations undertaken by both parties to this Agreement shall be continuous, and shall not be terminated when this Agreement terminates.

  
 Article 10 Breach Liability 
  

	10.1	Unless otherwise expressly provided for in this Agreement, the breach behavior of the parties to this Agreement include but not limited to the following situation:

  

	 	(1)	failure to comply with any undertakings and warranties made by the parties in this Agreement; 

  

	 	(2)	failure to comply with other obligations undertaken by the parties under this Agreement. 

  

	10.2	The Breaching Party shall be liable to the other party for its breach. The other party may give the Breaching Party a reasonable period and require the Breaching Party to remedy. If
the Breaching Party fails to take remedial measures within the reasonable period, the non-breaching party shall be entitled to terminate the contract. The Breaching Party shall indemnify the non-breaching party against all actual losses incurred
therefrom, including but not limited to all reasonable costs incurred by the non-breaching party for executing and performing this Agreement (including the costs and expenditures for engaging various intermediary agencies), but not exceeding the
losses that may be caused to the other party due to breach of this Agreement, which the breaching party foresees or should foresee when executing this Agreement. 

  
 Article 11 Termination 
  

	11.1	Provided that the other rights for termination are not affected, if the following occurs before the completion of the Acquisition: 

  

	 	(1)	Except as otherwise disclosed in this Agreement, if Yuande becomes aware of or receives a notice stating any warranties under this Agreement is inaccurate or is materially
misleading while Weixiao is unable to take reasonable actions to remedy before the completion of the Acquisition, and results in the material adverse effect on the value, business and financial aspects of the assets; or 

  

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	 	(2)	Weixiao is in serious breach or fails to comply with any warranties given under this Agreement, and Yuande reasonably believes that such breach and negligence will have a material
adverse effect on the value, business and financial aspect of the assets; 

  
 then it constitutes Weixiao’s breach in the provisions of this Agreement, and Yuande is entitled to issue a written notice to Weixiao, requiring Weixiao to take actions to remedy within a reasonable period. If
Weixiao fails to comply with the remedial requirements as stipulated in the notice, Yuande is entitled to terminate this Agreement and require Weixiao to indemnify. 
  

	11.2	Provided that any other rights of Weixiao under this Agreement is not affected, if before the Acquisition Yuande is in serious breach or fails to comply with any warranties stated
under this Agreement, then it constitutes Yuande’s breach in the provisions of this Agreement, and Weixiao is entitled to issue a written notice to Yuande, requiring Yuande to take action to remedy within a reasonable period. If Yuande fails to
comply with the the remedial requirements as stipulated in the notice, Weixiao is entitled to terminate this Agreement and require Yuande to indemnify. 

  
 Article 12 Costs 
  

	12.1	The parties to this Agreement shall respectively bear the costs, charges and expenditures incurred in respect of its consultations, drafts and completion of this Agreement and all
matters as contemplated by this Agreement, or other costs, charges and expenditures related to laws. 

  

	12.2	Weixiao and Yuande shall respectively pay for the taxes payable for completing the transaction contemplated by this Agreement in accordance with the provisions of applicable laws.

  
 Article 13 Validity 
  

	13.1	This Agreement shall become effective on the day when both parties sign this Agreement. 

  
 Article 14 Applicable Laws 
  

	14.1	Matters such as the validity, interpretation, performance and resolution of disputes of this Agreement shall be governed by the laws of the People’s Republic of China.

  
 Article 15 Dispute Resolution 

 

	15.1	 Any disputes caused by or in connection with this Agreement, including but not limited to the establishment, binding effect, performance, interpretation, breaching
liability, amendment and termination of this Agreement, shall be resolved by the 

  

 10 

	 	 
parties of this Agreement through friendly consultations. If no agreement is reached within 30 days after the occurrence of a dispute, a litigation in
respect of such dispute can be brought to a court having jurisdiction over such matter. The winning party is entitled to require the losing party to undertake the costs for professional persons (including but not limited to attorney fees) paid by
the winning party for the litigation and all other costs. 

  
 Article 16 General Provisions 
  

	16.1	If, according to any laws and regulations, any terms or other provisions of this Agreement becomes invalid, illegal or unenforceable, then as long as the economic and legal
substance of the transaction contemplated in this Agreement is not affected by material adverse effect on any party in any form, all other terms and provisions of this Agreement shall remain in full force and effect. When any terms or other
provisions shall be deemed void, illegal or unenforceable, the parties to this Agreement shall negotiate in good faith, make amendments to this Agreement, and realize the original intent of the parties as similar as possible in accordance with an
acceptable manner, so as to complete the transaction contemplated by this Agreement in accordance with the original plan to the possible maximum extent. 

  

	16.2	This Agreement is a complete document in respect of the contents involved in this Agreement for the parties. This Agreement together with any appendixes to this Agreement
constitutes a complete agreement between the parties of this Agreement. From the effective date of this Agreement, all intentions, expressions, understanding and agreement (whether it is oral or in writing) proposed to be performed for the
transactions under this Agreement prior to the effective date of this Agreements shall be void and superseded by this Agreement. 

  

	16.3	Except as otherwise provided by law, one party to this Agreement fails to exercise or delays to exercise its rights, powers or privileges under this Agreement shall not constitute a
waiver of such rights and powers or privileges; separate or partial exercise of such rights and powers or privileges shall not impede the exercise of any other rights and power or privileges. 

  

	16.4	The warranties stated in this Agreement shall remain in full force and effect after completion, and other than those matters which have already been performed, all the terms of this
Agreement shall continue to be valid after completion. 

  

	16.5	No revisions or amendments shall be made to this Agreement except by a written instrument executed by the parties of this Agreement. 

  

	16.6	All headings of the paragraphs are solely for the purpose of reading convenience and shall not affect the meanings or interpretations of the contents of this Agreement.

  

	16.7	The parties to this Agreement must take and sign or ensure to take and sign all further actions, acts, matters and documents necessary for the implementation of the terms of this
Agreement, so as to enable the transaction contemplated by this Agreement to be performed completely, and in order to enable Yuande to obtain the interests of the assets effectively, Weixiao shall complete, execute and perform all further actions,
deeds, documents and matters as reasonably required by Yuande when necessary, so as to enable Yuande to gain all of the interests under this Agreement without the prejudice of lien, mortgage, option, and encumbrance of property right or any adverse
circumstances. 

  

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	16.8	All appendixes to this Agreement shall be an inseparable part of this Agreement and shall have the same force and effect as this Agreement. 

  

	16.9	This Agreement has four originals. Each party holds two originals. Both parties may separately execute copies of this Agreement as necessary. 

  

 12 

 (There is no formal text on this page.) 
  

			
	 Beijing Weixiao Biological
 Technology
Development
 Company Limited
	  	/company chop/
		
	 Signature of legal representative or
 authorized representative:
	  	/s/
		
	 Beijing Yuande Bio-Medical
 Engineering Company
Limited
	  	/company chop/
		
	 Signature of legal representative or
 authorized representative:
	  	/s/

 Appendix 1    Reagent Kits for Clinical Diagnostics 
  

			
	1	  	SARS
	2	  	TSH
	3	  	T3
	4	  	FT3
	5	  	T4
	6	  	FT4
	7	  	LH
	8	  	FSH
	9	  	PRL
	10	  	T
	11	  	P
	12	  	E2
	13	  	INS
	14	  	C-P
	15	  	Ins-Ab
	16	  	HCG
	17	  	AFP
	18	  	CEA
	19	  	PSA
	20	  	Ferr
	21	  	CA125
	22	  	CA-50
	23	  	CA153
	24	  	CA199
	25	  	NSE
	26	  	FpSA
	27	  	GH

  

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 Appendix 2    Core Technology Staff 
  
 Xiudong Sun 
 Xiaoling Yang 
  

 15 

 Appendix 3    List of Patents 
  

			
	Invented Name of Patent:	    	Immunoassay Gene Analysis System
	Application No. :	    	01141479.0
	Application Date:	    	September 27, 2001

  

 16General Electric Ultrasound Equipment Supply Agreement

 English translation; for reference only 
  
 Exhibit 10.5 
  
 General Electric Ultrasound Equipment Supply Agreement 
  
 This General Electric Ultrasound Equipment Supply Agreement (hereinafter referred to as this “Agreement”) is entered into on March 19, 2003 by
and between Beijing Yuande Bio-Medical Engineering Co., Ltd., a limited liability joint stock company established and legally existing under the laws of the People’s Republic of China (hereinafter referred to as the “Company”), and GE
(China) Co., Ltd., a foreign-invested investment company established and legally existing under the laws of the People’s Republic of China (hereinafter referred to as “GE”). 
  
 Recital 
  
 WHEREAS: GE, the Company and the existing shareholders of the Company had signed a Stock Subscription and Purchase Agreement
(hereinafter referred to as “Subscription and Purchase Agreement”) on September 23, 2002; 
  
 WHEREAS: in accordance with the agreement of the Subscription and Purchase Agreement, the Company agrees, in accordance with the terms and conditions of
this Agreement, to purchase exclusively from GE or its Affiliates (as defined in Subscription and Purchase Agreement) any and all ultrasound equipment or other medical imaging equipment (“Equipment”) that, from the perspective of design,
is a component of, or for use with, the products of the Company and its Affiliates (“Product”) including but not limited to all equipments used in the Product for positioning, guiding, and image monitoring; 
  
 WHEREAS: GE’s performance of its obligations under the Subscription and
Purchase Agreement is conditioned upon the Company’s execution of this Agreement; 
  
 NOW, THEREFORE, in consideration of the aforesaid premises and the mutual agreements and covenants stipulated herein and in the Subscription and Purchase Agreement, both parties hereby reach the following legally
binding agreements: 
  
 1. Supply of Ultrasound Equipment 
  

	 	1.1	The Company hereby agrees, in accordance with the terms and conditions of this Agreement, to designate GE and its Affiliates as the exclusive supplier of all Equipments required for
the production of the Products. The Company undertakes that, without the prior written consent of GE, (1) the Company is not allowed to purchase any Equipment from any unit or individual other than from GE and its Affiliates, (2) every Product sold
by the Company must be installed with the Equipment supplied by GE. 

  

 1 

 English translation; for reference only 
  
 2. Order, Delivery, Price and Payment 
  

	 	2.1	No later than sixty (60) days prior to the date of delivery of each batch of Equipment, the Company shall sign a sales contract with GE regarding such Equipment. In the event the
terms of such sales contract conflict with this Agreement, the content of this Agreement shall prevail. 

  

	 	2.2	GE agrees that the price of the Equipment to be sold to the Company shall generally not be higher than the price of the same type of Equipment (depends on the specific sale) to be
sold to its distributor at the time a sales contract is entered into between GE or its Affiliates and the Company. The price of the Equipment that is custom made for the Company shall be determined separately by both parties through consultation.

  

	 	2.3	On the day each sales contract for the relevant Equipment is entered into with GE, the Company shall pay GE, in immediately available fund, fifty percent (50%) of the total
contractual price. Three (3) days before the Equipment is dispatched as stipulated by such contract, the Company shall pay GE, in immediately available fund, thirty percent (30%) of the total contractual price. On the day the “Equipment
Installation Acknowledgement Receipt Certificate” regarding the Equipment mentioned in such contract (but no later than thirty (30) days after the dispatch of the Equipment) is executed by the Company and GE, the Company shall pay GE, in
immediately available fund, twenty percent (20%) of the total contractual price. Once sold, all the Equipment is not returnable, except for exchange of the defective Equipment in accordance with Article 3.2. 

  

	 	2.4	All amount payable under this Agreement shall be calculated and made in Renminbi. In the circumstances where it is permitted by law, upon written agreement between the Company and
GE, such amount can also be calculated and paid in other currency. 

  

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	 	2.5	Fifteen (15) days after the end of each quarter, the Company shall submit a written report to GE listing the quantity of the Product sold by the Company in the preceding quarter.

  
 3. Warranty and Liability on Quality of Product

  

	 	3.1	GE warrants that all Equipment it supplies complies with the requirements of the relevant national standard and meets the quality standards as stated in its product manual or other
relevant technical information provided to the Company. After both parties to this Agreement specify the model number, specifications and other special requirement in the relevant sales contract, GE shall not assume any applicability warranty
relating to the Equipment. In addition, GE does not provide any other warranty on the quality of the Equipment, including but not limited to implied warranty and merchantability warranty. 

  

	 	3.2	GE agrees to provide, free of charge, one year repair service to the Company for the Equipment sold effective from the earlier occurrence of either of the following date: (i) the
date when the Equipment is installed in the Product; (ii) on the 90th day after the Equipment is delivered. During
the free repair period, GE shall repair or exchange the defective Equipment in accordance with the relevant repair policy then in effect and bear the relevant fees arising out of such repair or exchange. However, the maximum liability that GE bears
shall not exceed the total consideration that GE received in respect of such Equipment (excluding value added tax and other taxes). After the end of the free repair period, the Company may enter into an after-sale service agreement with GE or its
Affiliates to specify matters relating to after-sale services of the Equipment. GE agrees to provide after-sale service to the Company at preferential price. Such price shall not exceed the lowest price of the after-sale services for products of the
same model number of the Equipment provided by GE then in China. GE warrants that professional after-sale services shall be provided by qualified technicians. 

  

	 	3.3	Except otherwise expressly specified in this Agreement, neither party shall be liable to the any of the other party’s direct, special, ancillary, punitive losses, costs, and
fees regardless of its nature, including but not limited to loss of income or profit, increase in production cost arising out of the other party’s default, loss incurred due to the inability to enter into a contract with a third party, and
other similar causes arising out of this Agreement; neither party shall be liable to the 

  

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 other party for all losses, costs and fees arising out of any governmental or non-governmental litigation, arbitration,
administrative proceedings or petition in connection with this Agreement. The exemption of liability in this Article shall not be affected by the nature of cause of action or cause of petition (including but not limited to breach of contract,
tortuous and other legal causes) and it remains valid after the occurrence of default under this Agreement, the failure of the purpose of this Agreement, or the realization of the stipulated remedy of this Agreement. 
  
 4. Term and Termination 
  

	 	4.1	This Agreement shall continue to be valid before it is terminated in accordance with the provisions herein. This Agreement may be terminated upon mutual agreement of both parties
after consultation. 

  

	 	4.2	If GE makes any changes to any Equipment or suspend the production or supply of any Equipment, GE shall notify the Company ninety days in advance regarding such situation of change,
and suspension in production or supply. 

  

	 	4.3	After one hundred and eighty (180) days from the day the shares of the Company held by GE is lower than five percent (5%) of the aggregate number of issued and outstanding ordinary
shares of the Company, the Company may notify GE in writing to unilaterally terminate its obligation under Article 1.1 hereunder to exclusively purchase Equipment from GE. 

  

	 	4.4	After this Agreement is terminated, (i) the provisions of Articles 3.3, 4, 5 and 6 of this Agreement shall remain in effect; (ii) payment obligation accrued prior to the date of
termination, and obligations to purchase and deliver confirmed by orders of both parties, shall not be affected; (iii) the liability for breach arising out of any party’s act of default that occurred prior to the date of termination shall not
be affected. 

  

	 	4.5	If one party is unable to perform all or part of the obligations under this Agreement due to force majeure events that are reasonably beyond its control, such party shall suspend
the performance of its obligations during the period of the occurrence of the force majeure events, save and except that such party is at fault in relation to the occurrence of the force majeure events. “Force Majeure Event” includes but
is not limited to act of God, earthquake, typhoon, flood, fire, war, plague, civil unrest, events which is imposed by law and regulations after its occurrence as beyond the reasonable control of the party. 

  

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 5. Confidential Obligations 
  

	 	5.1	In this Agreement, “Confidential Information” shall mean the various clauses of this Agreement and all non-public data and information relating to any party in connection
with this Agreement, its business or operation and price determination, price adjustment stipulation, payment terms, quality warranty conditions and all other contractual terms relating to the design, production, use and sale of the relevant
Equipment disclosed or provided to the receiving party by the disclosing party or any of its employees or agents. However, Confidential Information shall not include the following information: (i) information that is available to the public without
breaching of any confidential obligation of the receiving party; (ii) at the time of disclosure the receiving party may reasonably proof that such information is known or commonly known within the industry; (iii) information that is obtained from
sources other than the disclosing party or any of its employees and such information is not restricted by any confidential obligations; (iv) information that is independently developed by the receiving party without referencing the Confidential
Information or without breaching this Agreement; (v) information that is expressly authorized by the disclosing party in writing for the permission of such disclosure; or (vi) information that is ordered to be disclosed by any law, regulation,
order, requirement, decree of any government or judicial department or authority; however, the receiving party shall promptly notify the disclosing party of such mandatory requirement so that the disclosing party may seek protective judgment in
relation to the relevant Confidential Information and to limit the disclosure of the specific Confidential Information only to the extent required by such government or judicial department. 

  

	 	5.2	The parties agree to treat all Confidential Information strictly confidential and without the prior written consent of one party, the other party shall not directly or indirectly
use or disclosed any Confidential Information to any person (including its employees), enterprise or company save and except the use and disclosure is necessary for the performance and observance of the provisions hereunder. The parties further
agree to establish and maintain a procedure to protect and safeguard the Confidential Information of the disclosing party and agree to procure the same degree of prudent measure in managing the Confidential Information as its own Confidential
Information and such standard shall in no event be lower than a reasonable prudent standard. 

  

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	 	5.3	The fact that certain Confidential Information may be disclosed in accordance with this provision shall not release the confidential obligation of the receiving party in preserving
the confidentiality of such Confidential Information in other manner. 

  

	 	5.4	The obligations of both parties under this Article shall remain valid after the termination of this Agreement. 

  
 6. General Provisions 
  

	 	6.1	All notices, petitions, claims, requests and other communications under this Agreement shall be made in writing and shall be sent by personal delivery, facsimile or registered mail
or postal mail (by prepaid postal mail, receipt requested) (it shall be deemed formally delivered at the time it is received) to the address as stated in Article 10.02 of the Subscription and Purchase Agreement by both parties.

  

	 	6.2	Except as otherwise specified in this Agreement, amendments can only be made in writing after it is signed by both parties to this Agreement. The party waiving its right may do so
in the form of signing a waiver document unilaterally waiving such right under this Agreement. 

  

	 	6.3	Failure or delay of either party in exercising any right, power or privilege shall not constitute a wavier of such party’s right, power or privilege. Individual or partial
exercise of certain right, power or privilege shall not exclude the further exercise of such right, power or privilege in other manner and shall not exclude its exercise of any other right, power and privilege. The right and remedy stipulated under
this Agreement is cumulative, and it shall not exclude any other right or remedy stipulated by laws and regulations. 

  

	 	6.4	If, in accordance with any laws or public policy, any of this Agreement’s terms or other provisions are invalid, then as long as, in relation to any party, the economic or
legal substance of the transaction stipulated by this Agreement are not subject to material adverse effect in any forms, all other terms and provisions of this Agreement shall remain in full force and effect. When any term or other provision is
determined to be invalid, illegal or unenforceable, parties to this 

  

 6 

 English translation; for reference only 
  
 Agreement shall negotiate in good faith to amend this Agreement, so as to materialize the original intents of the parties as
closely as possible in an acceptable manner in order that the transactions contemplated by this Agreement are consummated as originally contemplated to the greatest extent possible. 
  

	 	6.5	This Agreement and the Subscription and Purchase Agreement constitute the entire agreement between the parties to this Agreement with respect to the content of this Agreement. All
written and oral agreement and undertakings made prior to this Agreement and Subscription and Purchase Agreement shall be superseded. This Agreement is not assignable. However, GE may assign this Agreement or any right and obligation under this
Agreement to one or more Affiliates of GE without the consent of the Company. If GE assigns the obligations under this Agreement to its Affiliates, GE shall continue to be liable for the obligations that such Affiliates fail to perform.

  

	 	6.6	This Agreement shall be governed by and construed in accordance with the laws of China. 

  

	 	6.7	Any dispute arising out of the execution of, or relating to, this Agreement shall be resolved in accordance with Article 10.11 of the Subscription and Purchase Agreement.

  

	 	6.8	Unless it is otherwise stated, the terms being underlined in this Agreement shall have the meaning given to it by the relevant clauses within this Agreement.

  

	 	6.9	This Agreement is executed in Chinese and it can be separately executed and delivered (including through facsimile) in one or more counterparts. Each of the counterparts when
executed shall be deemed to be an original. All counterparts taken together shall constitute one and the same agreement. 

  
 [Next page is execution page] 
  

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 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first written above. 
  

			
	Beijing Yuande Bio-Medical Engineering Co., Ltd.
		
	Signed by:	 	 /s/ [and chopped]

	Name:	 	Wu Xiaodong
	Position:	 	General Manager
	
	GE (China) Co.,Ltd.
		
	Signed by:	 	 /s/ Chen Chih

	Name:	 	Chen Chih
	Position:	 	President
	 	 	GE (China) Co., Ltd. – Medical Group

  

 8 

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 Exhibit 10.5 
  
 General Electric Ultrasound Equipment Supply Agreement 
 Amendment Agreement 
  
 This amendment agreement
(hereinafter referred to as this “Agreement”) is executed on November 16, 2004 by and between Beijing Yuande Bio-Medical Engineering Co., Ltd., a limited liability company established and legally existing under the laws of the
People’s Republic of China (hereinafter referred to as the “Company”), and GE (China) Co., Ltd., a foreign-invested investment company established and legally existing under the laws of the People’s Republic of China (hereinafter
referred to as “GE”). 
  
 Recital 
  
 WHEREAS: GE and the Company had executed a “General Electric Ultrasound
Equipment Supply Agreement” (hereinafter referred to as the “Supply Agreement”) on March 19, 2003; 
  
 WHEREAS: because the Company intends to undergo re-organization and overseas listing, GE needs to transfer to an offshore affiliate company of GE the
equity interest in the Company held by GE; 
  
 WHEREAS: both
parties agree to make appropriate amendments to the Supply Agreement due to the Company’s re-organization and the equity transfer by GE. 
  
 NOW, THEREFORE, in consideration of the aforesaid premises and the mutual agreements and covenants stipulated in this Agreement and in the Supply
Agreement, both parties hereby reach the following legally binding agreements: 
  
 1. Article 4.3 
  
 Article 4.3 of the Supply
Agreement shall be replaced in its entirety by the following: “After one hundred and eighty (180) days from the day on which GE and its Affiliates directly or indirectly through one or more intermediate entities hold less than 5% of all of the
Company’s equity interest or outstanding issued shares, the Company may give written notification to GE and unilaterally terminate its obligation under Article 1.1 of this Agreement to exclusively purchase Equipment from GE or its Affiliates[;
except the cases whereby the direct or indirect holding, by GE and its Affiliates, of less than 5% of all of the Company’s equity interest or outstanding issued shares is caused by the fact that the Company or entities controlling the Company
increase capital or issue new shares.]” 
  

 1 

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 2. Entire Agreement 
  

	 	2.1	This Agreement constitutes the entire agreement reached by both parties regarding this Agreement’s main issues, and supersedes all written and oral agreements and undertakings
previously reached by both parties regarding this Agreement’s main issues. Unless amended by this Agreement, the Supply Agreement shall remain to be fully effective. 

  
 3. Severability 
  
 If, in accordance with any laws or public policy, any of this Agreement’s terms or other provisions are invalid, then as long as, in relation to any
party, the economic or legal substance of the transaction stipulated by this Agreement are not subject to material adverse effect in any forms, all other terms and provisions of this Agreement shall remain in full force and effect. When any term or
other provision is determined to be invalid, illegal or unenforceable, parties to this Agreement shall negotiate in good faith to amend this Agreement, so as to materialize the original intents of the parties as closely as possible in an acceptable
manner in order that the transactions contemplated by this Agreement are consummated as originally contemplated to the greatest extent possible. 
  
 4. Governing Law 
  
 This Agreement shall be governed by, and construed in accordance with, the laws of the People’s Republic of China (without consideration to the
provision regarding the conflict of laws). Any dispute relating to or arising from this Agreement shall be resolved in accordance with Article 6.7 of the Supply Agreement. 
  
 5. Counterparts 
  
 This Agreement may be executed and delivered (including by facsimile transmission) in one or more counterparts and separately executed by the various
parties thereto. Each of the counterparts when executed shall be deemed to be an original. All counterparts taken together shall constitute one and the same agreement. 
  

 2 

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 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first written above. 
  
  

									
	 	 	 	 	 	 	Beijing Yuande Bio-Medical Engineering Co., Ltd.
					
	 	 	 	 	 	 	Signed by:	 	 /s/ Wu Xiaodong

	 	 	 	 	 	 	Name:	 	Wu Xiaodong
	 	 	 	 	 	 	Position:	 	Chairperson
				
	 	 	 	 	 	 	GE (China) Co.,Ltd.
					
	 	 	 	 	 	 	Signed by:	 	 /s/ Chen Chih

	 	 	 	 	 	 	Name:	 	Chen Chih
	 	 	 	 	 	 	Position:	 	President
	 	 	 	 	 	 	 	 	GE (China) Co., Ltd. – Medical Group

  

 3

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