Document:

EX-10.1

 Exhibit 10.1 

STOCKHOLDER SUPPORT AGREEMENT 

STOCKHOLDER SUPPORT AGREEMENT, dated as of January 31, 2022 (this “Agreement”), by and among OTR Acquisition Corp., a
Delaware corporation (“SPAC”), Comera Life Sciences Holdings, Inc., a Delaware corporation (“Holdco”) and certain of the stockholders of Comera Life Sciences, Inc., a Delaware corporation (the
“Company”), whose names appear on the signature pages of this Agreement (each, a “Stockholder” and, collectively, the “Stockholders”). 

WHEREAS, SPAC, Holdco, CLS Sub Merger 1 Corp., a Delaware corporation (“Company Merger Sub”), CLS Sub Merger 2 Corp., a
Delaware corporation (“SPAC Merger Sub” and, together with Company Merger Sub, the “Merger Subs”), and the Company propose to enter into, on the date hereof, a business combination agreement (the
“BCA”; capitalized terms used but not defined in this Agreement shall have the meanings ascribed to them in the BCA), which provides, among other things, that, upon the terms and subject to the conditions thereof, (a) Company
Merger Sub will merge with and into the Company (the “Company Merger”), with the Company surviving the Company Merger as a direct wholly owned subsidiary of Holdco, and (b) immediately following the Company Merger, SPAC Merger
Sub will merge with and into SPAC (the “SPAC Merger” and, together with the Company Merger, the “Mergers”), with SPAC surviving the SPAC Merger as a direct wholly owned subsidiary of Holdco; and 

WHEREAS, as of the date hereof, each Stockholder owns of record the number of shares of Company Common Stock and Company Preferred Stock as
set forth opposite such Stockholder’s name on Exhibit A hereto (all such shares of Company Common Stock and Company Preferred Stock and any shares of Company Common Stock and Company Preferred Stock of which ownership of record or the
power to vote is hereafter acquired by the Stockholders prior to the termination of this Agreement being referred to herein as the “Shares”). 

NOW, THEREFORE, in order to induce SPAC to enter into the BCA and in consideration of the mutual covenants and agreements contained herein,
and intending to be legally bound hereby, the parties hereto hereby agree as follows: 
 1. Agreement to Vote. Subject to the earlier
termination of this Agreement in accordance with Section 5, each Stockholder, severally and not jointly, hereby agrees to vote at any meeting of the stockholders of the Company, and in any action by written consent of the
stockholders of the Company (which written consent shall be delivered promptly, and in any event within two (2) hours after the Company requests such delivery), all of the Shares held by such Stockholder at such time (i) in favor of the
approval and adoption of the BCA and approval of the Merger and all other transactions contemplated by the BCA and (ii) against any action, agreement, transaction or proposal that would result in a breach of any covenant, representation or
warranty or any other obligation or agreement of the Company under the BCA or that would reasonably be expected to result in the failure of the Merger from being consummated. Each Stockholder acknowledges receipt and review of a copy of the BCA.

 2. Transfer of Shares. Each Stockholder, severally and not jointly, agrees that it shall not, directly or indirectly,
(a) sell, assign, transfer (including by operation of law), lien, pledge, dispose of or otherwise encumber any of the Shares or otherwise agree to do any of the foregoing, except for a sale, assignment or transfer pursuant to the BCA or to
another stockholder of the Company that is a party to this Agreement and bound by the terms and obligations hereof, (b) deposit any Shares into a voting trust, enter into a voting agreement or arrangement or grant any proxy or power of attorney
with respect thereto that is inconsistent with this Agreement or (c) enter into any contract, option or other arrangement or undertaking with respect to the direct or indirect acquisition or sale, assignment, transfer (including by operation of
law) or other disposition of any Shares; provided that the foregoing shall not prohibit the transfer of the Shares by a Stockholder to an affiliate of such Stockholder, but only if such affiliate shall execute this Agreement or a joinder
agreeing to become a party to this Agreement. 

  
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 3. Trading Standstill. Each Stockholder, severally and not jointly, agrees that it
shall not, without SPAC’s prior written consent, directly or indirectly, sell, assign, transfer or otherwise dispose of any shares of SPAC Common Stock at any time between the date of this Agreement and the earlier of (a) the expiration of
the Redemption Rights pursuant to the SPAC Certificate of Incorporation, or (b) the termination of this Agreement in accordance with its terms. 

4. Representations and Warranties. Each Stockholder, severally and not jointly, represents and warrants to SPAC as follows: 

(a) The execution, delivery and performance by such Stockholder of this Agreement and the consummation by such Stockholder of the transactions
contemplated hereby do not and will not (i) conflict with or violate any United States or non-United States statute, law, ordinance, regulation, rule, code, executive order, injunction, judgment, decree
or other order applicable to such Stockholder, (ii) require any consent, approval or authorization of, declaration, filing or registration with, or notice to, any person or entity, (iii) result in the creation of any encumbrance on any
Shares (other than under this Agreement, the BCA and the agreements contemplated by the BCA) or (iv) conflict with or result in a breach of or constitute a default under any provision of such Stockholder’s governing documents. 

(b) As of the date of this Agreement, such Stockholder owns exclusively of record and has good and valid title to the Shares set forth
opposite such Stockholder’s name on Exhibit A free and clear of any security interest, lien, claim, pledge, proxy, option, right of first refusal, agreement, voting restriction, limitation on disposition, charge, adverse claim of
ownership or use or other encumbrance of any kind, other than pursuant to (i) this Agreement, (ii) applicable securities laws and (iii) the Company Certificate of Incorporation and the bylaws of the Company, and as of the date of this
Agreement, such Stockholder has the sole power (as currently in effect) to vote and right, power and authority to sell, transfer and deliver such Shares, and such Stockholder does not own, directly or indirectly, any other Shares. 

(c) Such Stockholder has the power, authority and capacity to execute, deliver and perform this Agreement and this Agreement has been duly
authorized, executed and delivered by such Stockholder. 
 5. Termination. This Agreement and the obligations of the Stockholders
under this Agreement shall automatically terminate upon the earliest of (a) the Effective Time; (b) the termination of the BCA in accordance with its terms and (c) the effective date of a written agreement of the parties hereto
terminating this Agreement. Upon termination of this Agreement, neither party shall have any further obligations or liabilities under this Agreement; provided that nothing in this Section 5 shall relieve any party of
liability for any willful material breach of this Agreement occurring prior to termination. The representations and warranties contained in this Agreement and in any certificate or other writing delivered pursuant hereto shall not survive the
Closing or the termination of this Agreement. 
 6. Miscellaneous. 

(a) Except as otherwise provided herein, all costs and expenses incurred in connection with this Agreement and the transactions contemplated
hereby shall be paid by the party incurring such costs and expenses, whether or not the transactions contemplated hereby are consummated. 

(b) All notices, requests, claims, demands and other communications hereunder shall be in writing and shall be given (and shall be deemed to
have been duly given upon receipt) by delivery in person, by e-mail or by registered or certified mail (postage prepaid, return receipt requested) to the respective parties at the following

  
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addresses or e-mail addresses (or at such other address or email address for a party as shall be specified in a notice given in accordance with this
Section 6(b)): 
 If to SPAC, to it at: 

OTR Acquisition Corp. 
 1395
Brickell Avenue, Suite 800 
 Miami, FL 33131 

Attention: Nicholas Singer 

Email: [●] 
 with a copy
to: 
 Greenberg Traurig, P.A. 

333 SE 2nd Avenue, Suite 4400 

Miami, Florida 33131 
 Attention:
Alan I. Annex, Esq. 
  Kenneth A. Gerasimovich, Esq. 

 Daniella G. Silberstein, Esq. 

Email:       [●] 

If to Holdco, to it at: 
 Comera
Life Sciences, Inc. 
 12 Gill Street, Suite 4650 

Woburn, MA 01801 
 Attn: Jeffrey
Hackman 
 Email: [●] 

with a copy to: 

Loeb & Loeb LLP 
 345
Park Avenue 
 New York, NY 10154 

Attention: Mitchell S. Nussbaum, Esq. 

Email: [●] 
 If to a
Stockholder, to the address or email address set forth for Stockholder on the signature page hereof. 
 (c) If any term or other provision
of this Agreement is invalid, illegal or incapable of being enforced by any rule of law, or public policy, all other conditions and provisions of this Agreement shall nevertheless remain in full force and effect so long as the economic or legal
substance of the transactions contemplated hereby is not affected in any manner materially adverse to any party. Upon such determination that any term or other provision is invalid, illegal or incapable of being enforced, the parties hereto shall
negotiate in good faith to modify this Agreement so as to effect the original intent of the parties as closely as possible in a mutually acceptable manner in order that the transactions contemplated hereby be consummated as originally contemplated
to the fullest extent possible. 
 (d) This Agreement constitutes the entire agreement among the parties with respect to the subject matter
hereof and supersedes all prior agreements and undertakings, both written and oral, among the parties, or any of them, with respect to the subject matter hereof. This Agreement shall not be assigned (whether pursuant to a merger, by operation of law
or otherwise), by any party without the prior express written consent of the other parties hereto. 

  
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 (e) This Agreement shall be binding upon and inure solely to the benefit of each party
hereto and their respective permitted assigns, and nothing in this Agreement, express or implied, is intended to or shall confer upon any other person any right, benefit or remedy of any nature whatsoever under or by reason of this Agreement. No
Stockholder shall be liable for the breach by any other Stockholder of this Agreement. 
 (f) This Agreement may not be amended, modified or
supplemented in any manner, whether by course of conduct or otherwise, except by an instrument in writing signed by each of the parties hereto. 

(g) The parties hereto agree that irreparable damage would occur in the event any provision of this Agreement was not performed in accordance
with the terms hereof and that the parties shall be entitled to specific performance of the terms hereof, in addition to any other remedy at law or in equity. 

(h) This Agreement shall be governed by, and construed in accordance with, the laws of the State of Delaware applicable to contracts executed
in and to be performed in that State. All Actions arising out of or relating to this Agreement shall be heard and determined exclusively in any Delaware Chancery Court. The parties hereto hereby (i) submit to the exclusive jurisdiction of the
Delaware Chancery Court for the purpose of any Action arising out of or relating to this Agreement brought by any party hereto, and (ii) irrevocably waive, and agree not to assert by way of motion, defense, or otherwise, in any such Action, any
claim that it is not subject personally to the jurisdiction of the above-named courts, that its property is exempt or immune from attachment or execution, that the Action is brought in an inconvenient forum, that the venue of the Action is improper,
or that this Agreement or the transactions contemplated hereunder may not be enforced in or by any of the above-named courts. 
 (i) This
Agreement may be executed and delivered (including by facsimile or portable document format (pdf) transmission) in counterparts, and by the different parties hereto in separate counterparts, each of which when executed shall be deemed to be an
original but all of which taken together shall constitute one and the same agreement. 
 (j) Each Stockholder hereby authorizes the Company,
Holdco and SPAC to publish and disclose in any announcement or disclosure required by the SEC such Stockholder’s identity and ownership of Shares and the nature of such Stockholder’s obligations under this Agreement; provided that
prior to any such publication or disclosure the Company, Holdco and SPAC have provided such Stockholder with an opportunity to review and comment upon such announcement or disclosure, which comments the Company, Holdco and SPAC will consider in good
faith. 
 (k) At the request of SPAC, in the case of any Stockholder, or at the request of the Stockholders, in the case of SPAC, and
without further consideration, each party shall execute and deliver or cause to be executed and delivered such additional documents and instruments and take such further action as may be reasonably necessary to consummate the transactions
contemplated by this Agreement. 
 (l) This Agreement shall not be effective or binding upon any Stockholder until after such time as the
BCA is executed and delivered by the Company, Holdco, SPAC and the Merger Subs. 
 (m) Notwithstanding anything herein to the contrary, each
Stockholder signs this Agreement solely in such Stockholder’s capacity as a stockholder of the Company, and not in any other capacity and, if applicable, this Agreement shall not limit or otherwise affect the actions of any affiliate, employee
or designee of such Stockholder or any of its affiliates in his or her capacity as an officer or director of the Company. 
 (n) Each of
the parties hereto hereby waives to the fullest extent permitted by applicable law any right it may have to a trial by jury with respect to any litigation directly or indirectly arising out of, under or in connection with this Agreement. Each of the
parties hereto (i) certifies that no Representative, agent or attorney of any other party has represented, expressly or otherwise, that such other party would not, in the 

  
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event of litigation, seek to enforce the foregoing waiver and (ii) acknowledges that it and the other parties hereto have been induced to enter into this Agreement and the transactions
contemplated hereby, as applicable, by, among other things, the mutual waivers and certifications in this Section 6(n). 

[Signature pages follow] 

  
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 IN WITNESS WHEREOF, the parties have executed this Agreement as of the date first written
above. 
  

			
	OTR ACQUISITION CORP.
		
	By:	 	/s/ Nicholas J. Singer
	Name:	 	Nicholas J. Singer
	Title:	 	Chief Executive Officer

  

			
	COMERA LIFE SCIENCES HOLDINGS, INC.
		
	By:	 	/s/ Jeffrey Hackman
	Name:	 	Jeffrey Hackman
	Title:	 	Chief Executive Officer

 [Signature Page to Stockholder Support Agreement] 

  
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 IN WITNESS WHEREOF, the parties have executed this Agreement as of the date first written
above. 
  

	
	/s/ James Sherblom
	James Sherblom
	Address: [●]
	Email: [●]

  

	
	/s/ Charles Cherington
	Charles Cherington
	Address: [●]
	Email: [●]

  

			
	PHOENIX VENTURE PARTNERS, LP
		
	By:	 	/s/ Zachariah Jonasson
	Name:	 	Zachariah Jonasson
	Title:	 	Managing Partner
	Address:	 	[●]
	Email:	 	[●]

  

			
	THE SOANE FAMILY TRUST
		
	By:	 	/s/ David Soane
	Name:	 	David Soane
	Title:	 	Trustee
	Address:	 	[●]
	Email:	 	 [●]

 [Signature Page to Stockholder Support Agreement] 

  
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 IN WITNESS WHEREOF, the parties have executed this Agreement as of the date first written
above. 
  

			
	CHERINGTON HOLDINGS LLC
		
	By:	 	 /s/ Charles Cherington

	Name:	 	Charles Cherington
	Title:	 	Partner
	Address:	 	[●]
	Email:	 	 [●]

  

			
	ASHLEY S. PETTUS 2012 IRREVOCABLE TRUST FBO BENJAMIN P. CHERINGTON
		
	By:	 	 /s/ Charles Cherington

	Name:	 	Charles Cherington
	Title:	 	Trustee
	Address:	 	[●]
	Email:	 	 [●]

  

			
	ASHLEY S. PETTUS 2012 IRREVOCABLE TRUST FBO CYRUS P. CHERINGTON
		
	By:	 	 /s/ Charles Cherington

	Name:	 	Charles Cherington
	Title:	 	Trustee
	Address:	 	[●]
	Email:	 	[●]

  

			
	ASHLEY S. PETTUS 2012 IRREVOCABLE TRUST FBO HENRY P. CHERINGTON
		
	By:	 	 /s/ Charles Cherington

	Name:	 	Charles Cherington
	Title:	 	Trustee
	Address:	 	[●]
	Email:	 	[●]

 [Signature Page to Stockholder Support Agreement] 

  
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 EXHIBIT A 

LIST OF STOCKHOLDERS 
  

									
	 Name of Stockholder
	  	Number of Shares of
Company Common
Stock Owned	 	  	Number of Shares of
Company Preferred
Stock Owned	 
	 James Sherblom
	  	 	400,000	 	  	 	—  	 
	 Charles Cherington LLC
	  	 	—  	 	  	 	1,348,062	 
	 Charles Cherington
	  	 	—  	 	  	 	210,971	 
	 Ashley S. Pettus 2012 Irrevocable Trust FBO Benjamin P. Cherington
	  	 	—  	 	  	 	101,286	 
	 Ashley S. Pettus 2012 Irrevocable Trust FBO Cyrus P. Cherington
	  	 	—  	 	  	 	101,286	 
	 Ashley S. Pettus 2012 Irrevocable Trust FBO Henry P. Cherington
	  	 	—  	 	  	 	101,286	 
	 Phoenix Venture Partners LP
	  	 	—  	 	  	 	4,070,274	 
	 The Soane Family Trust
	  	 	—  	 	  	 	3,470,129	 

  
 9EX-10.2

 Exhibit 10.2 

EXECUTION VERSION 
 SPONSOR
SUPPORT AGREEMENT 
 SPONSOR SUPPORT AGREEMENT, dated as of January 31, 2022 (this “Agreement”), by and among OTR
Acquisition Sponsor LLC, a Delaware limited liability company (“Sponsor”), Comera Life Sciences, Inc., a Delaware corporation (the “Company”) and OTR Acquisition Corp., a Delaware corporation
(“SPAC”). Capitalized terms used but not defined in this Agreement shall have the meanings ascribed to such terms in the BCA (as defined below). 

WHEREAS, concurrently with the execution and delivery of this Agreement, SPAC, the Company, Comera Life Sciences Holdings, Inc., a Delaware
corporation (“Holdco”), CLS Sub Merger 1 Corp., a Delaware corporation (“Company Merger Sub”), CLS Sub Merger 2 Corp., a Delaware corporation (“SPAC Merger Sub” and, together with Company Merger
Sub, the “Merger Subs”), are entering into a Business Combination Agreement (the “BCA”), dated as of the date hereof, pursuant to which, among other things, (a) Company Merger Sub will merge with and into the
Company (the “Company Merger”), with the Company surviving the Company Merger as a direct wholly owned subsidiary of Holdco, (b) immediately following the Company Merger, SPAC Merger Sub will merge with and into SPAC (the
“SPAC Merger” and, together with the Company Merger, the “Mergers”), with SPAC surviving the SPAC Merger as a direct wholly owned subsidiary of Holdco; 

WHEREAS, as of the date hereof, Sponsor owns beneficially and of record 2,611,838 shares of SPAC Class B Common Stock, par value $0.0001
per share (“Sponsor SPAC Shares”); and 
 WHEREAS, in order to induce SPAC and the Company to enter into the BCA, each of
Sponsor, SPAC and the Company desires to enter into this Agreement. 
 NOW, THEREFORE, in consideration of the foregoing and of the mutual
covenants and agreements contained herein, the receipt and sufficiency of which is hereby acknowledged, and intending to be legally bound, the parties hereto hereby agree as follows: 

1. Voting Obligations. Until the earlier of (a) the Closing or (b) termination of the BCA in accordance with Article IX
thereof, Sponsor agrees that, at the SPAC Stockholders’ Meeting and in connection with any written consent of the stockholders of SPAC, Sponsor shall vote (or duly and promptly execute and deliver an action by written consent), or cause to be
voted at such meeting (or cause such consent to be duly and promptly executed and delivered with respect to), all of the Sponsor SPAC Shares (i) in favor of the approval and adoption of the BCA, the Transactions and any other proposal submitted
for approval by the stockholders of SPAC in connection with the Transactions, including the Extension Proposal (if applicable), and (ii) against any action, agreement, transaction or proposal that would result in a breach of any covenant,
representation or warranty or any other obligation or agreement of SPAC under the BCA or that would reasonably be expected to delay the consummation of the Transactions, increase the likelihood of the failure of the consummation of the Transactions
or result in the failure of the Transactions from being consummated. This Section 1 shall be void and of no force and effect if the BCA shall be terminated in accordance with its terms or the Closing shall not occur for any
reason. 
 2. Waiver of Redemption Rights. Sponsor agrees not to (a) demand that SPAC redeem the Sponsor SPAC Shares in
connection with the Transactions or (b) otherwise participate in any such redemption by tendering or submitting any of the Sponsor SPAC Shares for redemption. This Section 2 shall be void and of no force and effect if
the BCA shall be terminated in accordance with its terms or the Closing shall not occur for any reason. 

  
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 3. Waiver of Anti-Dilution Rights. Sponsor hereby waives the provisions of
Section 4.3(b)(ii) of the SPAC Certificate of Incorporation relating to the adjustment of the Initial Conversion Ratio (as defined in the SPAC Certificate of Incorporation) in connection with the Transactions. This
Section 3 shall be void and of no force and effect if the BCA shall be terminated in accordance with its terms or the Closing shall not occur for any reason. 

4. Working Capital Loans. As contemplated by the SPAC Warrant Agreement and the prospectus filed in connection with SPAC’s
initial public offering, Sponsor may (but shall not be required to) make working capital loans to SPAC in the aggregate amount of up to $2,500,000, which shall be convertible, at the option of Sponsor, into SPAC Warrants at a price of $1.00 per SPAC
Warrant. 
 5. Representations and Warranties. Sponsor represents and warrants to the Company and SPAC as follows: 

(a) The execution, delivery and performance by Sponsor of this Agreement and the consummation by Sponsor of the transactions contemplated
hereby do not and will not (i) conflict with or violate any Law applicable to Sponsor, (ii) require any consent, approval or authorization of, declaration, filing or registration with, or notice to, any person, (iii) result in the
creation of any encumbrance on any SPAC Common Stock (other than under this Agreement, the BCA and the agreements contemplated by the BCA) or (iv) if applicable, conflict with or result in a breach of or constitute a default under any provision
of Sponsor’s certificate of formation and limited liability company agreement, as amended, modified or supplemented from time to time. For purposes of this Agreement, “person” shall have the meaning ascribed to such term in the BCA.

 (b) As of the date of this Agreement, Sponsor (i) owns exclusively of record and has good and valid title 2,611,838 shares of SPAC
Class B Common Stock free and clear of any security interest, lien, claim, pledge, proxy, option, right of first refusal, agreement, voting restriction, limitation on disposition, charge, adverse claim of ownership or use or other encumbrance
of any kind, other than pursuant to (A) this Agreement, (B) applicable securities Laws, and (C) the SPAC Organizational Documents, and (ii) has the sole power (as currently in effect) to vote and right, power and authority to
sell, transfer and deliver such shares of SPAC Class B Common Stock, and Sponsor does not own, directly or indirectly, any other SPAC Common Stock. 

(c) Sponsor has the power, authority and capacity to execute, deliver and perform this Agreement and this Agreement has been duly authorized,
executed and delivered by Sponsor. 
 6. Termination. This Agreement and the obligations of Sponsor under this Agreement shall
automatically terminate upon the earliest of: (a) the last date on which a party hereto has any obligations hereunder in accordance with the terms hereof; (b) the termination of the BCA in accordance with its terms; and (c) the mutual
written agreement of the parties hereto. Upon termination or expiration of this Agreement, no party shall have any further obligations or liabilities under this Agreement; provided, however, such termination or expiration shall not
relieve any party from liability for fraud or willful material breach of this Agreement occurring prior to its termination. 

7. Miscellaneous. 

(a) All notices, requests, claims, demands and other communications hereunder shall be in writing and shall be given (and shall be deemed to
have been duly given upon receipt) by delivery in person, by email or by registered or certified mail (postage prepaid, return receipt requested) to the respective parties at the following addresses or email addresses (or at such other address or
email address for a party as shall be specified in a notice given in accordance with this Section 7(a)): 

  
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 If to Sponsor or, prior to the Closing, SPAC, to: 

OTR Acquisition Corp. 
 1395
Brickell Avenue, Suite 800 
 Miami, FL 33131 

Attention: Nicholas Singer 

Email: [●] 
 with a copy
to: 
 Greenberg Traurig, P.A. 

333 SE 2nd Avenue, Suite 4400 

Miami, Florida 33131 

Attention:    Alan I. Annex, Esq. 

    Kenneth A. Gerasimovich, Esq. 

    Daniella G. Silberstein, Esq. 

Email:         [●] 

If to the Company or, following the Closing, SPAC, to: 

Comera Life Sciences, Inc. 
 12
Gill Street, Suite 4650 
 Woburn, MA 01801 

Attention: Jeff Hackman 
 Email:
[●] 
 with a copy to: 

Loeb & Loeb LLP 
 345
Park Avenue 
 New York, NY 10154 

Attention: Mitchell S. Nussbaum, Esq. 

Email: [●] 
 (b) If any
term or other provision of this Agreement is invalid, illegal or incapable of being enforced by any rule of law, or public policy, all other conditions and provisions of this Agreement shall nevertheless remain in full force and effect so long as
the economic or legal substance of the transactions contemplated hereby is not affected in any manner materially adverse to any party. Upon such determination that any term or other provision is invalid, illegal or incapable of being enforced, the
parties hereto shall negotiate in good faith to modify this Agreement so as to effect the original intent of the parties as closely as possible in a mutually acceptable manner in order that the transactions contemplated hereby be consummated as
originally contemplated to the fullest extent possible. 
 (c) (i) The words “hereof”, “herein”, and
“hereunder” and words of similar import, when used in this Agreement, shall refer to this Agreement as a whole and not to any particular provision of this Agreement; (ii) the words “date hereof,” when used in this Agreement,
shall refer to the date set forth in the Preamble; (iii) the terms defined in the singular have a comparable meaning when used in the plural, and vice versa; (iv) the terms defined in the present tense have a comparable meaning when used
in the past tense, and vice versa; (v) any references herein to a specific Section or Article shall refer, respectively, to Sections or Articles of this Agreement; (vi) references herein to any gender (including the neuter gender) includes
each other gender; 

  
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(vii) the word “or” shall not be exclusive; (viii) the headings herein are for convenience of reference only, do not constitute part of this Agreement and shall not be deemed
to limit or otherwise affect any of the provisions hereof; and (ix) the parties hereto have participated jointly in the negotiation and drafting of this Agreement and, in the event that an ambiguity or question of intent or interpretation
arises, this Agreement shall be construed as jointly drafted by the parties hereto and no presumption or burden of proof shall arise favoring or disfavoring any party by virtue of the authorship of any provision of this Agreement. 

(d) This Agreement is intended to create, and creates, a contractual relationship and is not intended to create, and does not create, any
agency, partnership, joint venture or any like relationship between the parties hereto. 
 (e) This Agreement (together with the BCA, to the
extent referred to in this Agreement) constitutes the entire agreement among the parties with respect to the subject matter hereof and supersedes all prior agreements and undertakings, both written and oral, among the parties, or any of them, with
respect to the subject matter hereof. This Agreement shall not be assigned (whether pursuant to a merger, by operation of law or otherwise) by any party without the prior written consent of the other parties hereto. 

(f) This Agreement shall be binding upon and inure solely to the benefit of each party hereto (and each of SPAC’s and Sponsor’s
permitted assigns), and nothing in this Agreement, express or implied, is intended to or shall confer upon any other person any right, benefit or remedy of any nature whatsoever under or by reason of this Agreement. 

(g) The parties agree that irreparable damage would occur if any provision of this Agreement were not performed in accordance with the terms
hereof, and, accordingly, that the parties shall be entitled to an injunction or injunctions to prevent breaches of this Agreement or to enforce specifically the performance of the terms and provisions hereof in the Court of Chancery of the State of
Delaware or, if that court does not have jurisdiction, any court of the United States located in the State of Delaware, without proof of actual damages or otherwise, in addition to any other remedy to which they are entitled at law or in equity as
expressly permitted in this Agreement. Each of the parties hereby further waives (i) any defense in any action for specific performance that a remedy at law would be adequate, and (ii) any requirement under any Law to post security or a
bond as a prerequisite to obtaining equitable relief. 
 (h) This Agreement shall be governed by, and construed in accordance with, the Laws
of the State of Delaware applicable to contracts executed in and to be performed in that State. All Actions arising out of, under or in connection with this Agreement or the transactions contemplated hereby shall, to the fullest extent permitted by
applicable Law, be heard and determined exclusively in the Court of Chancery of the State of Delaware; provided that if jurisdiction is not then available in the Court of Chancery of the State of Delaware, then any such legal Action may be
brought in any federal court located in the State of Delaware or any other Delaware state court. To the fullest extent permitted by applicable Law, the parties hereto hereby (i) irrevocably submit to the exclusive jurisdiction of the aforesaid
courts for themselves and with respect to their respective properties for the purpose of any Action arising out of or relating to this Agreement or the transactions contemplated hereby brought by any party hereto, and (ii) agree not to commence
any Action relating thereto except in the courts described above in the State of Delaware, other than Actions in any court of competent jurisdiction to enforce any judgment, decree or award rendered by any such court in the State of Delaware as
described herein. To the fullest extent permitted by applicable Law, each of the parties further agrees that notice as provided herein shall constitute sufficient service of process and the parties further waive any argument that such service is
insufficient. To the fullest extent permitted by applicable Law, each of the parties hereby irrevocably and unconditionally waives, and agrees not to assert, by way of motion or as a defense, counterclaim or otherwise, in any Action arising out of
or relating to this Agreement or the transactions contemplated hereby, (A) any claim that it is not personally subject to the jurisdiction of the courts in Delaware as described herein for any reason, (B) that it or its property is exempt
or immune from jurisdiction of any such court or from any legal process commenced in such courts (whether through service of notice, attachment prior to judgment, attachment in aid of execution of judgment, execution of judgment or otherwise) and
(C) that (x) the Action in any such 

  
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court is brought in an inconvenient forum, (y) the venue of such Action is improper, or (z) this Agreement, or the subject matter hereof, may not be enforced in or by such courts. 

(i) This Agreement may be executed and delivered (including by facsimile or portable document format (pdf) transmission) in one or more
counterparts, and by the different parties hereto in separate counterparts, each of which when executed shall be deemed to be an original but all of which taken together shall constitute one and the same agreement. 

(j) Without further consideration, each party shall execute and deliver or cause to be executed and delivered such additional documents and
instruments and take all such further action as may be reasonably necessary or desirable to consummate the transactions contemplated by this Agreement. 

(k) This Agreement shall not be effective or binding upon any party hereto until after such time as the BCA is executed and delivered by SPAC,
Holdco, the Merger Subs and the Company. 
 (l) Each of the parties hereto hereby waives to the fullest extent permitted by applicable
Law, any right it may have to a trial by jury with respect to any litigation directly or indirectly arising out of or relating to this Agreement or the transactions contemplated hereby. Each of the parties hereto (i) certifies that no
representative, agent or attorney of any other party has represented, expressly or otherwise, that such other party would not, in the event of litigation, seek to enforce the foregoing waiver, and (ii) acknowledges that it and the other parties
hereto have been induced to enter into this Agreement and the transactions contemplated hereby, as applicable, by, among other things, the mutual waivers and certifications in this Section 7(l). 

[Signature pages follow] 

  
 5 

 IN WITNESS WHEREOF, the parties have executed this Agreement as of the date first written
above. 
  

			
	OTR ACQUISITION SPONSOR LLC
		
	By	 	/s/ Nicholas J. Singer
	Name:	 	Nicholas J. Singer
	Title:	 	Managing Member

  

			
	OTR ACQUISITION CORP.
		
	By	 	/s/ Nicholas J. Singer
	Name:	 	Nicholas J. Singer
	Title:	 	Chief Executive Officer

 Signature Page to Sponsor Support Agreement 

 IN WITNESS WHEREOF, the parties have executed this Agreement as of the date first written
above. 
  

			
	COMERA LIFE SCIENCES, INC.
		
	By	 	/s/ Jeffrey Hackman
	Name:	 	Jeffrey Hackman
	Title:	 	Chief Executive Officer

 Signature Page to Sponsor Support Agreement

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