Document:

First Amendment to Office Lease

 Exhibit 10.19 
 601 GATEWAY BOULEVARD 
 FIRST AMENDMENT TO OFFICE LEASE

 This FIRST AMENDMENT TO OFFICE LEASE (this “First Amendment”) is made and entered into as of
October 31, 2011 by and between GATEWAY CENTER, LLC, a Delaware limited liability company (“Landlord”), and HYPERION THERAPEUTICS, INC., a Delaware corporation (“Tenant”). 

RECITALS 
 A. Landlord and Tenant entered into that certain Office Lease dated September 6, 2007 (the “Original Lease”), whereby Landlord leased to Tenant and Tenant leased from Landlord a
total of 12,215 rentable square feet of space located on the second (2nd) floor of that certain office building at 601 Gateway Boulevard in South San Francisco, California (the “Building”) and commonly known as Suite 200 and Suite 250 (the
“Premises”). 
 B. Tenant desires, and Landlord has agreed, to (i) extend the term of the Lease with
respect to Suite 200 only (the “Renewal Premises”), which Renewal Premises are shown on the exhibit attached hereto as Exhibit A and which Renewal Premises shall consist of approximately 8,167 rentable square feet, for a
period of eighteen (18) months and (ii) make certain other modifications to the Original Lease, and in connection therewith Landlord and Tenant desire to amend the Original Lease on the terms and conditions contained herein. 

AGREEMENT 

NOW THEREFORE, in consideration of the foregoing recitals and the mutual covenants contained herein, and for other good and valuable
consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto hereby agree as follows: 
 1.
Defined Terms. All capitalized terms not otherwise defined herein shall have the same meaning as is given such terms in the Original Lease. From and after the date hereof, all references in the Original Lease and herein to the
“Lease” shall mean and refer to the Original Lease as amended hereby. 
 2. Renewal Premises Extended Term.
Landlord and Tenant acknowledge and agree that the Lease Term for the Premises is scheduled to expire on January 31, 2012 (the “Scheduled Expiration Date”) pursuant to the terms of the Original Lease. Notwithstanding
anything to the contrary in the Lease, the term of Tenant’s lease of the Renewal Premises only shall expire on August 31, 2013 (the “Extended Term Expiration Date”), unless sooner terminated in accordance with the Lease.
The period of time commencing on February 1, 2012 (the “Extended Term Commencement Date”) and terminating on the Extended Term Expiration Date shall be referred to as the “Extended Term.” The Lease Term shall
expire as to all that portion of the Premises less the Renewal Premises (the “Termination Premises”) on the Scheduled Expiration Date in accordance with the terms of the Original Lease and all rights and

  
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obligations of Landlord and Tenant as to the Termination Premises shall be subject to and in accordance with the terms of the Original Lease; provided, however, that if the current subtenant of
the Termination Premises remains in the Termination Premises after the Scheduled Expiration Date pursuant to a direct lease with Landlord or otherwise with Landlord’s written consent, then the provisions of Article 15 of the Original Lease
shall not apply as between Landlord and Tenant as to the Termination Premises and Tenant shall be released from all obligations thereunder. Effective upon the Extended Term Commencement Date, all references in the Lease to the “Lease Term”
shall mean and refer to the Extended Term, all references in the Lease and herein to the “Lease Expiration Date” or “expiration of the Lease Term” shall mean and refer to the Extended Term Expiration Date, and all references in
the Lease and herein to the “Premises” shall mean and refer to the Renewal Premises. 
 3. Base Rent.
Commencing on the Extended Term Commencement Date, and continuing throughout the Extended Term, Tenant shall pay Base Rent for the Renewal Premises in accordance with the following schedule: 

 

													
	 Period During Extended Term
	  	Annual Base
Rent	 	  	Monthly
Installment
of Base Rent	 	  	Monthly Base Rental
Rate Per Rentable
Square Foot of the
Existing
Premises	 
	 February 1, 2012 — August 31, 2013
	  	$	235,209.60	  	  	$	19,600.80	  	  	$	2.40	  

 4. Tenant’s Share of Direct Expenses. Notwithstanding anything to the contrary in the
Lease, prior to the Extended Term Commencement Date, Tenant shall continue to pay Tenant’s Share of Building Direct Expenses for the Premises in accordance with the terms of the Original Lease. Commencing on the Extended Term Commencement Date,
and continuing throughout the Extended Term, Tenant shall continue to pay Tenant’s Share of Building Direct Expenses in accordance with the terms of the Lease; provided however, (i) Tenant’s Share shall equal 3.7849%, and
(ii) the Base Year shall be calendar year 2012; provided further, however, the Base Year shall be the period from July 1, 2011 through June 30, 2012 for purposes of calculating Tenant’s Share of Tax Expenses only. 

5. Condition of Premises. Tenant hereby acknowledges that Tenant is currently in possession of the Premises and that,
except as set forth in the Original Lease and the Tenant Work Letter, neither Landlord nor any agent of Landlord has made any representation or warranty regarding the condition of the Premises, the Renewal Premises, the Building or the Project, or
with respect to the suitability of any of the foregoing for the conduct of Tenant’s business. Except as expressly set forth in this First Amendment, Landlord shall not be obligated to provide or pay for any improvement work or services related
to the improvement of the Renewal Premises, and Tenant shall continue to accept the Premises in its presently existing, “as-is” condition. Tenant hereby acknowledges and agrees that any improvements, alterations, additions or changes to
the Premises shall be completed pursuant to the terms and conditions of Article 8 of the Lease. 

  
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 6. Landlord Work. Landlord shall construct or cause to be constructed a
demising wall as shown in Exhibit A, attached hereto and incorporated herein by this reference; provided that, Tenant hereby agrees that, notwithstanding Tenant’s occupancy of the Renewal Premises during the construction of such demising
wall by Landlord, Landlord shall be permitted to construct such demising wall during normal business hours, without any obligation to pay overtime or other premiums, and the construction of such demising wall by Landlord shall in no way constitute a
constructive eviction of Tenant nor entitle Tenant to any abatement of Rent, and Landlord shall have no responsibility or for any reason be liable to Tenant for any direct or indirect injury to or interference with Tenant’s business arising
from the construction of such demising wall, nor shall Tenant be entitled to any compensation or damages from Landlord for loss of the use of the whole or any part of its retained portion of the Premises or of Tenant’s personal property or
improvements resulting from the construction of such demising wall, or for any inconvenience or annoyance occasioned by the construction of such demising wall. 
 7. Security Deposit/Return of Letter of Credit. 
 (a)
Security Deposit. Prior to the Extended Term Commencement Date, Tenant shall deposit with Landlord a security deposit (the “Security Deposit”) in the amount of Thirty-Nine Thousand Two Hundred Ninety-Two and 80/100
Dollars ($39,292.80), as security for the faithful performance by Tenant of all of its obligations under the Lease. If Tenant is in uncured default under Article 19.1 with respect to any provisions of the Lease, including, but not limited to,
the provisions relating to the payment of Rent, the removal of property and the repair of resultant damage, Landlord may, without notice to Tenant, but shall not be required to apply all or any part of the Security Deposit for the payment of any
Rent or any other sum in default and Tenant shall, upon demand therefor, restore the Security Deposit to its original amount. Any unapplied portion of the Security Deposit shall be returned to Tenant, or, at Landlord’s option, to the last
assignee of Tenant’s interest hereunder, within sixty (60) days following the expiration of the Extended Term. Tenant shall not be entitled to any interest on the Security Deposit and Landlord shall have the right to commingle the Security
Deposit with Landlord’s other funds. Tenant hereby waives the provisions of Section 1950.7 of the California Civil Code and all other provisions of law, now or hereafter in effect, which (i) establish the time frame by which a
landlord must refund a security deposit under a lease, and/or (ii) provide that a landlord may claim from a security deposit only those sums reasonably necessary to remedy defaults in the payment of rent, to repair damage caused by a tenant or
to clean the premises, it being agreed that Landlord may, in addition, claim those sums specified in this Section 7(a) above and/or those sums reasonably necessary to compensate Landlord for any loss or damage caused by Tenant’s
default of the Lease, including, but not limited to, all damages or rent due upon termination of the Lease pursuant to Section 1951.2 of the California Civil Code. 
 (b) Return of Letter of Credit. Upon receipt of the cash Security Deposit or upon receipt of confirmation from Landlord’s bank that any check conveying the Security Deposit has cleared,
Landlord shall promptly (and in any event within fifteen (15) days) release and return the L/C (as such term is defined in Section 21.3 of the Original Lease) to Tenant’s bank and effective as of the date of such return of the
L/C to Tenant’s bank, Article 21 of the Original Lease shall be deleted in its entirety. 

  
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 8. Signage. Landlord and Tenant acknowledge that Tenant has existing Building
standard signage in the ground floor lobby of the Building and adjacent to the Premises, pursuant to Article 23 of the Original Lease. Should Tenant require any additional signage in connection with the Renewal Premises or for the Extended
Term, Tenant acknowledges that any such additional signage shall be at Tenant’s sole cost and expense and shall be otherwise subject to all the terms and conditions set forth in Article 23 of the Original Lease. 

9. Brokers. Landlord and Tenant hereby warrant to each other that they have had no dealings with any real estate broker or
agent other than Studley (“Tenant’s Broker”) and Jones Lang LaSalle (“Landlord’s Broker”) in connection with the negotiation of this First Amendment and that they know of no real estate broker or agent other than
Tenant’s Broker and Landlord’s Broker who is entitled to a commission in connection with this First Amendment. Landlord shall pay any commission due to Tenant’s Broker and Landlord’s Broker in connection with this First Amendment
pursuant to a separate agreement between Landlord and Landlord’s Broker. Each party agrees to indemnify and defend the other party against and hold the other party harmless from any and all claims, demands, losses, liabilities, lawsuits,
judgments, and costs and expenses (including, without limitation, reasonable attorneys’ fees) with respect to any leasing commission or equivalent compensation alleged to be owing on account of any dealings with any real estate broker or agent
other than Landlord’s Broker and Tenant’s Broker. The terms of this Section 9 shall survive the expiration or earlier termination of this First Amendment or the Lease. 

10. No Further Modification. Except as specifically set forth in this First Amendment, all of the terms and provisions of
the Lease shall remain unmodified and in full force and effect. In the event of any conflict between the terms and conditions of the Lease, and the terms and conditions of this First Amendment, the terms and conditions of this First Amendment shall
prevail. 
 REMAINDER OF PAGE INTENTIONALLY LEFT BLANK 

  
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 IN WITNESS WHEREOF, this First Amendment has been executed as of the day and year first
above written. 
  

			
	“Landlord”:
	
	 GATEWAY CENTER LLC,

a Delaware limited liability company

		
	BY:	 	BOSTON PROPERTIES LIMITED PARTNERSHIP, a Delaware limited partnership, its sole member
		
		 	 BY:  BOSTON PROPERTIES, INC,
a Delaware corporation,
its general partner

		
		 	
          BY:  /s/  Rod  Diehl

		 	 Rod  Diehl

Senior  Vice  President,  
Leasing

  

			
	“Tenant”:
	
	 HYPERION THERAPEUTICS, INC, a
 Delaware corporation

		
	By:	 	/s/ Donald J. Santel
		 	 Name: Donald J. Santel

Title: CEO

		
	By:	 	/s/ Jeff Farrow
		 	 Name: Jeff Farrow
 Title:
CFO

  
 Page 5Fifth Amendment to Rights Agreement, effective as of April 12, 2012

 Exhibit 4.1 
 FIFTH AMENDMENT TO RIGHTS AGREEMENT 
 This Fifth Amendment, dated as of
April 12, 2012 (“Amendment”), and effective as of the date set forth below, amends that certain Rights Agreement, dated as of December 20, 1994 (as amended, “Rights Agreement”), as amended on
August 14, 1996 (“First Amendment”), December 11, 2000 (“Second Amendment” ), December 17, 2004 (“Third Amendment”), and November 10, 2009 (“Fourth Amendment,”
and together with the First Amendment, the Second Amendment and the Third Amendment, the “Former Amendments”), between RF Monolithics, Inc., a Delaware corporation (the “Company”), and Computershare Trust Company,
N.A. (formerly known as EquiServe Trust Company, N.A. and successor rights agent to Fleet National Bank) (“Rights Agent”). 
 WHEREAS, the Company and the predecessor of the Rights Agent entered into the Rights Agreement specifying the terms of the Rights (as defined therein); 

WHEREAS, the Company, Murata Electronics North America, Inc., a Texas corporation (“Parent”), and Ryder Acquisition
Company, Limited, a Delaware corporation and wholly owned subsidiary of Parent (“Merger Sub”), intend to enter into an Agreement and Plan of Merger (as may be amended from time to time, the “Merger Agreement”)
pursuant to which, among other things, and subject to the terms and conditions set forth in the Merger Agreement, Merger Sub will merge with and into the Company (the “Merger”) and each share of common stock of the Company that is
issued and outstanding immediately prior to the Merger will be converted into the right to receive cash consideration, upon the terms and subject to the conditions of the Merger Agreement, and the Company will survive the Merger and become a wholly
owned subsidiary of Parent; 
 WHEREAS, pursuant to Section 27 of the Rights Agreement, the Company desires to amend the
Rights Agreement as set forth below; and 
 WHEREAS, the Board of Directors of the Company has approved this Amendment.

 NOW, THEREFORE, in consideration of the premises and the mutual agreements herein set forth, the parties hereby agree as
follows: 
 Section 1. Certain Definitions. For purposes of this Amendment, capitalized terms not otherwise defined
herein shall have the meanings given them in the Rights Agreement. 
 Section 2. Amendments. The Rights Agreement is
hereby amended as follows: 
 (a) Section 1.1 of the Rights Agreement is hereby amended by adding the
following new paragraphs at the end of Section 1.1: 
 “Notwithstanding anything in this Agreement that might
otherwise be deemed to the contrary, neither Murata Manufacturing Co., Ltd., a Japanese corporation, Murata Electronics North America, Inc., a Texas corporation (“Parent”) nor any of its Affiliates or Associates (including, without
limitation, Ryder Acquisition Company, Limited (“Merger Sub”)) (collectively, the “Exempted Parties”) shall be deemed an Acquiring Person and none of the Distribution Date or Shares Acquisition Date shall be deemed to occur, in
each such case, by the announcement, approval, execution, delivery or performance of the Agreement and Plan of Merger dated on or about April 12, 2012, including any amendment or supplement thereto (the “Merger Agreement”) among
Parent, Merger Sub and the Company, including the consummation of the merger of Merger Sub with and 

 
into the Company and the other transactions contemplated by the Merger Agreement (collectively, the “Exempted Transactions”). Furthermore, none of the Exempted Parties shall be deemed
to be a Beneficial Owner of, or to own, any Common Shares or other securities of the Company or any Subsidiary of the Company by virtue of or as a result of any Exempted Transaction. 

For the avoidance of doubt, in no event shall the Exempted Transactions entitle or permit the holders of the Rights to exercise the
Rights under this Agreement and the Rights will not separate from the Common Shares as a result of the Exempted Transactions, it being the purpose of the Company in adopting this Amendment that none of the Exempted Transactions shall in any respect
give rise to any provisions of this Agreement.” 
 (b) Clause (i) of Section 7(a) of the Rights
Agreement shall be amended and restated in its entirety to read as follows: 
 “(i) the earlier of (A) the close of
business on December 20, 2014 or (B) immediately prior to the Effective Time (as defined in the Merger Agreement and of which the Company will give the Rights Agent twenty four (24) hours advance notice), but only if such Effective
Time shall occur (the earlier of (A) and (B) being herein referred to as the “Final Expiration Date”)”. 
 (c) A new Section 35 is hereby added to the end of the Rights Agreement, which new Section 35 shall read in its entirety as follows: 

“Section 35. Termination. On the Final Expiration Date, (a) this Agreement shall be terminated and be without any further force
or effect, (b) none of the parties to this Agreement will have any rights, obligations or liabilities hereunder and (c) the holders of the Rights shall not be entitled to any benefits, rights or other interests under this Agreement,
including, without limitation, the right to purchase or otherwise acquire Preferred Stock or any other securities of the Company.” 
 Section 3. Date of Effectiveness. This Amendment shall be deemed effective as of April 12, 2012, as if executed by both parties hereto on such date, and prior to the execution of the
Merger Agreement. 
 Section 4. Effect of Amendment. Except as expressly amended hereby and by the Former
Amendments, the Rights Agreement shall remain in full force and effect. 
 Section 5. Severability. If any term,
provision, covenant or restriction of this Amendment is held by a court of competent jurisdiction or other authority to be invalid, void or unenforceable, the remainder of the terms, provisions, covenants and restrictions of this Amendment shall
remain in full force and effect and shall in no way be affected, impaired or invalidated. 
 Section 6. Governing
Law. This Amendment and each Right Certificate issued hereunder shall be deemed to be a contract made under the laws of the State of Delaware and for all purposes shall be governed by and construed in accordance with the laws of such State
applicable to contracts to be made and performed entirely within such State. 

 Section 7. Counterparts. This Amendment may be executed in any number of
counterparts and each of such counterparts shall for all purposes be deemed to be an original, and all such counterparts shall together constitute but one and the same instrument. A signature to this Amendment transmitted electronically shall have
the same authority, effect, and enforceability as an original signature. 
 Section 8. Descriptive Headings.
Descriptive headings of the several Sections of this Amendment are inserted for convenience only and shall not control or affect the meaning or construction of any of the provisions hereof. 

[Signature page follows] 

 IN WITNESS WHEREOF, parties hereto have caused this Amendment to be duly executed and
effective as of the date set forth above. 
  

			
	RF MONOLITHICS, INC.
		
	By:	 	 /s/ Farlin A. Halsey

	Name:	 	Farlin A. Halsey
	Title:	 	President and Chief Executive Officer

  

			
	COMPUTERSHARE TRUST COMPANY, N.A.
		
	By:	 	 /s/ Dennis V. Moccia

	Name:	 	Dennis V. Moccia
	Title:	 	Manager, Contract Administration

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