Document:

Unassociated Document

    Equity
      Transfer
      Contract

     

    This
      contract is made and entered into by and betweenæ 

     

    
      
        	
                Shanghai
                  Wanxing Bio-pharmaceuticals Co., Ltd. 

              
	 
	
                Endorser:

              	
                (hereinafter
                  referred to as “party
                  A”)

              
	 	 
	
                The
                  natural persons:

              	
                (hereinafter
                  referred to as” Party
                  B”)

              

      

    

     

    Liang
      Hong
      with
      Identification No: 320502195002050528

    Sun
      Zhigang
      with
      Identification No: 320503194810210536

    Gu
      Mintong with
      Identification No: 320502196111180510

    Dai
      Jianping
      with
      Identification No: 320503196710102545

    Zhao
      Suqin with
      Identification No: 32050219600207154

     

    Whereas
      Suzhou
      Boai Medical Development Company is a pharmaceutical distribution company
      located in Suzhou with authorized capital of 10 million RMB. The Company had
      been GSP certificated by Chinese Food and Drug Administration and has two 100%
      owned subsidiaries, one sells vaccines, and the other medical devices. The
      natural persons above (Party A) hold 100% of the equity of Suzhou Boai Medical
      Development Company and intend to transfer their equity to Shanghai Wanxing
      Bio-pharmaceuticals Co., Ltd. (Party A);

     

    Now
      therefore,
      for
      good and valuable consideration, and abide by applicable rules of the laws
      of
      the Peoples Republic of China, the parties agree as follows:

     

    1.
      Object of transfer

    
      
        	
                The
                  equity proportion of Party A on Suzhou Boai Medical Development
Company
                  is: Liang
                  Hong :83.5%, 
                  Sun
                  Zhigang :7%, 
                  Gu
                  Mintong :5%, 
                  Dai
                  Jianping:3%,  Zhao
                  Suqin: 1.5%. All
                  of these persons agree to transfer 90% of their total equity of
                  Suzhou
                  Boai Medical Development Company to Party A. After the closing
                  of this
                  transfer, Party A will hold 90% of equity of Suzhou Baoi, Liang
                  Hong of
                  Party B will hold 10%, the other persons of Party B (Sun Zhigang,
                  Gu
                  Mintong, Dai Jianping and Zhao Suqin) will not hold
                  any.

              

      

    

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

     

    2.
      Price of transfer

    Based
      on
      the 10 million authorized capital of Suzhou Boai, the price of transfer is
      finally decided to be two times of the authorized capital depending on the
      Due
      Diligence report. That means Party A should pay 18 million RMB to Party B for
      this transfer. 

     

    3.
      Payment terms:

    During
      3
      days after signing of this contract, Party A shall pay 30% of the transfer
      fee
      to Party B.

    During
      one week after registration of equity alteration, Party A shall pay 55% of
      the
      transfer fee to Party B.

    At
      half
      year after registration of equity alteration, Party A shall pay 15% of the
      transfer fee to Party B, but party A keeps the right to take out receivables
      happened before June 30 of 2007 and/or the other bad debt losses from other
      receivables.

     

    4.Duty
      of Transferee

    Party
      B
      guarantees that the equity to be transferred to Party A is its legally 100%
      owned property without any mortgage or hypothec. Party B also promises that
      in
      the business process of Suzhou Boai before signing this contract, the company
      observed discipline and laws and paid tax according to the regulations of the
      government, otherwise Parties B will take full economic and legal
      responsibilities.

    (2)After
      receiving 30% of the transfer fee (include earnest) from Party A, Party B shall
      be responsible for the government administrative approval affairs and go through
      the alteration registration procedure as soon as possible.

    (3)After
      the closing of this contract only Liang Hong of Party A keeps as a shareholder
      of the company and benefits the profit and bears the risk of the company
      according to her fresh equity proportion.

     

    5.
      Duty of the Endorser

    (1)Party
      A shall pay transfer fee to Party B within the time limit specified in this
      contract. 

    (2)Party
      A shall provide all the documents required by administrative office for the
      approval application of this transfer. 

    (3)After
      the closing of this contract, party B shall benefit the profit and bear the
      risk
      of the company according to the fresh equity.

    (4)
      After
      the closing of this contract, a new Board of Directors with three directors,
      two
      from Party A, one from Party B (Liang Hong), will be organized. The President
      will be elected.

     

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

     

    6.
      Alteration and cancellation 

    The
      alteration of this contract shall be negotiated by two parties and entered
      into
      effective by signing a new alteration agreement. This contract may be cancelled
      in the following conditions:

    (1)
      With
      force majeure or reason inescapable, the alteration of the equity can’t be
      approved or registered, this contract will be automatically terminated.
      Simultaneously Party B should return the transfer fee received from Party A
      (include earnest ) to Party A. 

    (2)
      Either party may terminate this contract if the other party fails to perform
      his
      contractual obligation. The Party who exercises the right of cancellation should
      notify the other party in writing. The notice may be delivered by facsimile,
      e-mail or registered letter. The date of receiving this notice will be the
      time
      of cancellation of this contract. 

     

    7.
      Liabilities for breach of contract

    (1)
      Either party fails to perform his contractual obligation shall take full
      economic and legal responsibility.

    (2)Neither
      party shall take responsibility for the termination of this contract because
      of
      not approval of the administrative office.

     

    8.Governing
      Law

    This
      contract will be governed exclusively by and construed and enforced in
      accordance with the laws of the People’s Republic of China. Any dispute of the
      two parties shall be settled by friendly consultation. Otherwise the case shall
      be referred to the court with jurisdiction. 

     

    9.Others

    This
      contract is executed in ten counterparts, which will be separately kept by
      Party
      A and the five persons of Party B, and the left shall be delivered to
      administrative office for record.

     

    Transferee(Party
      A): Shanghai Wanxing Bio-pharmaceuticals Co., Ltd.

     

    
      	 	/s/ Zhuang Zhong (corporate seal of
              Party
              A)

    

     

    
      
        
          
          

        

        
          
          

          
            

          

        

        
          
          

        

      

    

     

    
      
        	
                Endorser(Party
                  B): 

              	 
	
                Liang
                  Hong 

              	Sun
                Zhigang 
	
                /s/
                  Liang Hong

              	
                /s/
                  Sun Zhigang

              
	 	 
	
                Gu
                  Mintong 

              	Dai
                Jianping 
	
                /s/
                  Gu Mintong

              	
                /s/
                  Dai Jianping

              
	 	 
	
                Zhao
                  Suqin

              	 
	
                /s/
                  Zhao SuqinUnassociated Document

    

    EXHIBIT
      4.3

     

    FIRST
      AMENDMENT TO LEASE 

     

    This
      FIRST AMENDMENT TO LEASE (this "Amendment") is entered into as of the
      1st
      day of
      June, 2007 by and between SFERS
      REAL ESTATE K LIMITED PARTNERSHIP,
      an Ohio
      limited partnership, by RREEF MANAGEMENT COMPANY, a Delaware corporation
      ("Landlord"), and BIO-BRIDGE
      SCIENCE INC., a
      Delaware corporation ("Tenant"), for certain premises located in the building
      commonly known as 1211 West 22nd
      Street,
      Oak Brook, Illinois (the "Building").

    

    RECITALS

    

    WHEREAS,
      Landlord and Tenant are parties to that certain Lease with a Lease Reference
      Date of July 20, 2004 (the "Lease") for approximately 1,253 rentable square
      feet
      on the sixth floor of the Building commonly known as Suite #615 (the
      "Premises"); and 

    

    WHEREAS,
      the term of the Lease is scheduled to expire on August 31, 2007.

    

    WHEREAS,
      Landlord and Tenant desire to extend the term of the Lease as set forth herein.
      

    

    NOW,
      THEREFORE, in consideration of the foregoing recitals and for other good and
      valuable consideration, the receipt and sufficiency of which are hereby
      acknowledged, Landlord and Tenant hereby agree to amend the Lease as
      follows:

    

    AGREEMENT

     

    Capitalized
      Terms.
      All
      capitalized terms used herein shall have the same meanings ascribed to them
      in
      the Lease, unless otherwise defined in this Amendment.

     

    Term.
      The Term of the Lease is hereby extended by three (3) years commencing September
      1, 2007 and continuing until August 31, 2010 (the "Renewal Term") on the terms
      and conditions herein contained and otherwise contained in the
      Lease.

     

    Rent
      Schedule.
      During the Renewal Term, Tenant shall pay the Annual Rent and the Monthly
      Installments thereof as follows: 

     

    
      	
              Period

            	
              Annual
                Rent 

              per
                square foot

            	
              Annual
                Rent

            	
              Monthly
                Installment 

              of
                Rent

            
	
              9/1/07-9/30/07

            	
              $0.00

            	
              $0.00

            	
              $0.00

            
	
              10/1/07-8/31/08

            	
              $21.75

            	
              $27,252.75

            	
              $2,271.07

            
	
              9/1/08-8/31/09

            	
              $22.25

            	
              $27,879.25

            	
              $2,323.27

            
	
              9/1/09-8/31/10

            	
              $22.75

            	
              $28,505.75

            	
              $2,375.45

            

    

     

    4. Base
      Year.
      The
      Base Year (Expenses) shall be 2007 and the Base Year (Taxes) shall be 2007
      (payable in 2008). 

    

    5. Condition
      of Premises.
      Landlord hereby agrees to shampoo the carpet in the Premises and replace all
      light bulbs that are not operational. Except as set forth herein, Tenant agrees
      that Landlord shall have no obligation to perform any construction or make
      any
      improvements or alterations in connection with this Amendment, and Tenant
      acknowledges and agrees that all construction obligations of Landlord, or
      agreements to provide allowances therefor, under the Lease have been performed
      in full and accepted.

     

    6. Brokers.
      Tenant
      represents and warrants to Landlord that no real estate broker, agent,
      commissioned salesperson or other person has represented Tenant in the
      negotiations of this Amendment. Tenant agrees to indemnify and hold Landlord
      harmless from and against any claim for any such commissions, fees or other
      form
      of compensation by any such third party claiming through the Tenant, including
      without limitation, any brokers specifically named in the Lease, including
      without limitation, any and all claims, causes of action, damages, costs and
      expenses, including attorneys' fees, associated therewith.

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

    

    7. Incorporation.
      Except as otherwise amended herein, all other terms and conditions of the Lease
      shall remain in full force and effect and Tenant hereby ratifies and confirms
      its obligations thereunder. Tenant acknowledges that as of the date of this
      Amendment, Tenant (i) is not in default under the terms of the Lease; (ii)
      has
      no defense, set off or counterclaim to the enforcement by Landlord of the terms
      of the Lease; and (iii) is not aware of any action or inaction by Landlord
      that
      would constitute an event of default under the Lease.

     

    8. Tenant's
      Authority.
      

     

    If
      Tenant signs as a corporation, partnership, trust or other legal entity each
      of
      the persons executing this Amendment on behalf of Tenant represents and warrants
      that Tenant has been and is qualified to do business in the state in which
      the
      Building is located, that the entity has full right and authority to enter
      into
      this Amendment, and that all persons signing on behalf of the entity were
      authorized to do so by appropriate actions. Tenant agrees to deliver to
      Landlord, simultaneously with the delivery of this Amendment, a corporate
      resolution, proof of due authorization by partners, opinion of counsel or other
      appropriate documentation reasonably acceptable to Landlord evidencing the
      due
      authorization of Tenant to enter into this Amendment.

     

    Tenant
      hereby represents and warrants that neither Tenant, nor any persons or entities
      holding any legal or beneficial interest whatsoever in Tenant, are (i) the
      target of any sanctions program that is established by Executive Order of the
      President or published by the Office of Foreign Assets Control, U.S. Department
      of the Treasury ("OFAC"); (ii) designated by the President or OFAC pursuant
      to
      the Trading with the Enemy Act, 50 U.S.C. App. § 5, the International Emergency
      Economic Powers Act, 50 U.S.C. §§ 1701-06, the Patriot Act, Public Law 107-56,
      Executive Order 13224 (September 23, 2001) or any Executive Order of the
      President issued pursuant to such statutes; or (iii) named on the following
      list
      that is published by OFAC: "List of Specially Designated Nationals and Blocked
      Persons." If the foregoing representation is untrue at any time during the
      Term,
      an Event of Default will be deemed to have occurred, without the necessity
      of
      notice to Tenant.

    

    9.
       Limitation
      of Landlord's Liability.
      Redress
      for any claim against Landlord under the Lease or Amendment shall be limited
      to
      and enforceable only against and to the extent of Landlord's interest in the
      Building. The obligations of Landlord under the Lease as amended hereby are
      not
      intended to be and shall not be personally binding on, nor shall any resort
      be
      had to the private properties of, any of its or its investment manager's
      trustees, directors, officers, partners, beneficiaries, members, stockholders,
      employees, or agents, and in no case shall Landlord be liable to Tenant
      hereunder for any lost profits, damage to business, or any form of special,
      indirect or consequential damages.

     

    IN
      WITNESS WHEREOF, Landlord and Tenant have executed this Amendment as of the
      day
      and year first written above.

     

    
      	LANDLORD: 	 	TENANT: 	 	 
	 	 	 	 	 	 
	
              SFERS
                REAL ESTATE K LIMITED 

              PARTNERSHIP,
                an Ohio limited partnership 

            	 	BIO-BRIDGE
              SCIENCE INC., a Delaware corporation 	 
	 	 	 	 	 	 
	By: RREEF
              Management Company, a Delaware corporation	 	By:	Dr.
              Liang Qiao /s/	
            
	 	 	 	Name: 	Dr.
              Liang
              Qiao 	 
	By: 	Mark
              Sabatino/s/	 	Title: 	Chief
              Executive
              Officer	 
	 	
              Mark
                Sabatino

              Vice
                President, District Manager

               

            	 	
               

              Dated:
                June 1,
                2007

            	 
	Dated:
              June 1,
              2007

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