Document:

Exhibit 10.53  

PART-TIME EMPLOYMENT AGREEMENT  

        This Part-Time Employment Agreement (this "Agreement"), dated as of January 1, 2004 is entered into by and between Melvin D. Booth (the
"Employee") and MedImmune, Inc., a Delaware corporation (the "Company"). 

Recitals  

        A.    The Employee has been employed by the Company as its President and Chief Operating Officer under the terms of an
Employment Agreement, dated as of August 15, 2002 (the "Prior Employment Agreement") which is being terminated pursuant to this Agreement effective as of the close of business on
December 31, 2003; and 

        B.    The Company desires to enter into a part-time employment relationship with Employee, and Employee wishes to
accept such part-time employment relationship, upon the terms and conditions set forth in this Agreement, effective as of January 1, 2004. 

        In
consideration of and in reliance upon the foregoing and the covenants, obligations and agreements contained herein, the Company and Employee hereby agree as follows: 

Agreement  

        1.    Employment.    The Prior Employment
Agreement is terminated effective as of the close of business on December 31, 2003. The Company hereby employs the Employee, and the Employee hereby accepts part-time employment by
the Company effective as of January 1, 2004, on the terms and conditions set forth in this Agreement. 

        2.    Term.    Subject to the provisions for early termination, the
employment of the Employee hereunder will be for the period commencing on January 1, 2004 and ending on December 31, 2004. Such period may be extended by mutual written consent of the
Company and the Employee. The period of the Employee's employment under this Agreement, as it may be terminated or extended from time to time as provided herein, is referred to hereafter as the
"Employment Period." 

        3.    Duties and Responsibilities.    During the Employment Period,
the Employee's duties and responsibilities to the Company will be as set forth on Annex A, a copy of which is attached. The Employee also agrees that during the Employment Period he will
provide the Company with assistance with respect to any issues involving the Company as to which he may have knowledge based on any specific activities undertaken while he was President and Chief
Operating Officer or as is reasonably requested by the Chief Executive Officer of the Company. During the Employment Period, the Employee will report to the Chief Executive Officer of the Company and
the Employee agrees he will faithfully perform his duties and responsibilities to the Company under the supervision of, and in the manner prescribed by, the Chief Executive Officer of the Company. The
Company will provide the Employee with such equipment and supplies (including, but not limited to, a computer and cell phone) as it determines appropriate for the Employee to perform his duties and
responsibilities hereunder. The Company will also provide such administrative assistance as the Employee may need to perform his assigned tasks for the Company. The Employee will submit regular
reports (monthly) on a written and/or oral basis to the Chief Executive Officer concerning the Employee's activities that month. The Employee agrees to take such actions reasonably requested by the
Chief Executive Officer from time to time to remove the Employee from positions of authority within the Company held by the Employee when the Employee was President and Chief Operating Officer. The
Employee agrees to comply with all Company policies applicable to employees of the Company including, but not limited to, the Company's Confidential Information and Securities Trading Policy. 

        4.    Time to be Devoted to Employment.    During the Employment
Period, the Employee will devote such time as is necessary to perform his duties and responsibilities as a part-time employee but in no 

 

event
will Employee be required to work more than 20 hours per week or 32 hours per month. It is initially anticipated that the Employee will be available one day per month, either
on-site or available by phone and e-mail, and it is the Company's responsibility to direct the Employee to undertake certain activities during the time the Employee will make
himself available. For clarity, the Employee's obligations as a member of the Company's Board of Directors (or any committee of the Board of Directors) will not count towards these maximum hour
requirements. 

        5.    Compensation; Reimbursement.    

        (a)    Base Salary.    During the Employment Period, the Company will
pay the Employee at the rate of $50,000 per annum, payable in semimonthly pay periods. For any such services rendered as a part-time employee during any calendar month in excess of
8 hours, Employee shall be compensated at the lesser of $500 per hour or $3,500 per day. The Employee will remain on the Company's payroll and will have all applicable taxes withheld and will
provide the Company with time sheets and accounts for all hours worked. For clarity, hours spent by the Employee in his capacity as a member of the Board of Directors (or any committee of the Board of
Directors) will not be subject to compensation under this Section 5(a). If the Employee is asked to serve as a member of the board of directors,
an officer or in another similar role of any entity (other than the Company or its subsidiaries) as a representative or designee of the Company or any of its subsidiaries (e.g., as a board member of a
MedImmune Ventures, Inc. portfolio company), the Employee will be compensated at the annual rate of $30,000 for that service (pro-rated for any partial year period during which the
Employee is serving in such role and payable in equal installments during semimonthly pay periods during the Employment Period), and such service will not count towards the employee's maximum hour
requirements set forth in Section 4 or otherwise included in the calculation of the number of hours for which the Employee is otherwise compensated under this  Section 5(a). The Employee
acknowledges that, in accordance with Company policy, any compensation offered or received by the Employee for service
with an entity as a representative or designee of the Company or any of its subsidiaries must be transferred to the Company or, if the compensation is in the nature of a personal right that cannot
easily be transferred, must be held for the benefit of the Company and exercised at the direction of the Company's Chief Executive Officer. 

        (b)    Benefits.    During the Employment Period, the Employee will be
entitled to participate in such employee benefit plans or programs of the Company, and will be entitled to such other fringe benefits, as are from time to time made available by the Company generally
to part-time employees with the Employee's number of work hours, position, tenure, salary, age, health and other qualifications. The Employee acknowledges and agrees that the Company does
not guarantee the adoption or continuance of any particular employee benefit plan or program or other fringe benefit during the Employment Period, and participation by the Employee in any such plan or
program will be subject to the rules and regulations applicable thereto. As an employee member of the Board of Directors, the Employee will not be entitled to compensation benefits available to
non-employee board members. 

        (c)    Stock Options.    The Employee is currently a party to stock
option agreements entered into with the Company for stock options granted on October 5, 1998, February 24, 1999, February 17, 2000, February 15, 2001, February 21,
2002 and February 20, 2003 (each an "Option Agreement" and collectively, the "Option Agreements"). The parties agree and the Employee understands and acknowledges that the Option Agreements are
hereby amended so that, notwithstanding anything in the Option Agreements to the contrary, (1) stock options that are not vested as of December 31, 2003 will be deemed to be immediately
forfeited, (2) stock options that are vested under these agreements as of December 31, 2003 may be exercised by the Employee until 90 days after the expiration of this Agreement
and (3) if the Employee is terminated by the Company for any reason that would have constituted "Cause" as defined in the Prior Employment Agreement or upon occurrence of an event 

2

 

described
in Section 7(b) (for the purpose of this Agreement any such reason shall be deemed  "Cause"), all stock options will immediately be forfeited upon
termination 

        (d)    Expenses.    During the Employment Period, the Company will
(1) reimburse the Employee, in accordance with the practices in effect from time to time for other staff personnel of the Company at the same level at which Employee was generally entitled to
be reimbursed before he became a part-time employee, for all reasonable and necessary traveling expenses and other disbursements incurred by the Employee for or on behalf of the Company in
the performance of the Employee's duties hereunder, upon presentation by the Employee to the Company of appropriate vouchers, (2) provide funding for the Employee's travel to and attendance at
professional meetings, as approved by the Chief Executive Officer of the Company and (3) provide the required tools and materials to Employee to perform his duties. For clarity, time spent for
any travel to or from the Company's premises will not be included in determining the number of hours worked by the Employee or for which the Employee is entitled to compensation under  Section 4 or
Section 5(a). 

        6.    Termination of Employment.    The Employee's employment with the
Company during the Employment Period may be terminated (a) on account of the death of the Employee, (b) on account of a voluntary termination by the Employee for any reason or
(c) by the Company for cause, which shall be defined as in Employee's Prior Employment Agreement, as amended herein. 

        7.    Effect of Termination of Employment.    

        (a)   Upon the termination of the Employee's employment during the Employment Period, neither the Employee nor the Employee's
beneficiaries or estate will have any further rights or claims against the Company under this Agreement except the right to receive (1) the unpaid portion of the base salary provided for in  Section 5(a)
 hereof, (2) payment of his accrued but unpaid rights in accordance with the terms of any incentive compensation, stock
option, retirement, employee welfare or other employee benefit plans or programs of the Company in which the Employee is then participating in accordance with  Section 5(b) or Section 5(c) hereof and (3) reimbursement for any expenses for
which the Employee shall not have been previously reimbursed as provided in Section 5(d) hereof. 

        (b)   In the event that, subsequent to termination of employment hereunder, the Employee (1) breaches any of the
provisions of Section 8 or Section 9 hereof or (2) directly or indirectly makes or
facilitates the making of any adverse public statements or disclosures with respect to the business or securities of the Company, all payments and benefits to which the Employee may otherwise have
been entitled pursuant to this Agreement shall immediately terminate and be forfeited, and any portion of such amounts as may have been paid to the Employee shall forthwith be returned to the Company. 

        8.    Disclosure of Information.    The Employee will not, at any time
during or after the Employment Period, disclose to any person, firm, corporation or other business entity, except as required by law, any non-public information concerning the technology,
know-how, trade secrets, business, products, clients or affairs of the Company or any subsidiary of the Company for any reason or purpose whatsoever, nor will the Employee make use of any
of such non-public information for personal purposes or for the benefit of any person, firm, corporation or other business entity except the Company or any subsidiary of the Company;
provided, however, the Employee may disclose the terms of this Agreement to a prospective employer, attorney, accountant, financial advisor or immediate family member of the Employee. 

        9.    Restrictive Covenant.    

        (a)   The Employee hereby acknowledges and recognizes that, during the Employment Period, the Employee will be privy to trade
secrets and confidential proprietary information critical to the Company's business and, accordingly, the Employee agrees that, in consideration of the benefits to be received by the Employee
hereunder, the Employee will not, during the Employment Period, (1) engage in any activity that would be directly competitive with a specific product or product 

3

 

candidate
being researched, developed or marketed by the Company or any subsidiary of the Company (a "Competing Business"), it being understood that this restriction is not intended to be a general
prohibition on the ability of the Employee to work in the fields of oncology, infectious disease or autoimmunity or (2) induce other employees of the Company or any subsidiary of the Company to
terminate their employment with the Company or any subsidiary of the Company or to engage in any Competing Business. This obligation will be in addition to any similar obligation to which the Employee
is otherwise subject. Notwithstanding the foregoing, the term "Competing Business" shall not include any business or activity that was not conducted by the Company or any subsidiary of the Company
during the Employment Period. 

        (b)   The Employee understands that the foregoing restrictions may limit the ability of the Employee to earn a livelihood in a
business similar to the business of the Company, but nevertheless believes that the Employee has received and will receive sufficient consideration and other benefits, as an employee of the Company
and as otherwise provided hereunder, to justify such restrictions which, in any event (given the education, skills and ability of the Employee), the Employee believes would not prevent the Employee
from earning a living. 

        10.    Intellectual Property.    Employee will promptly disclose,
grant and assign to Company, for its sole use and benefit, all inventions, improvements, technical information and suggestions relating in any way to the business of Company which Employee may develop
or acquire during the term of this Agreement, together with all patent applications, letters patent, copyrights and reissues thereof that may at any time be granted for or upon any such invention,
improvement or technical information. 

        11.    Enforcement.    It is the desire and intent of the parties
hereto that the provisions of this Agreement be enforceable to the fullest extent permissible under the laws and public policies applied in each jurisdiction in which enforcement is sought.
Accordingly, to the extent that a restriction contained in this Agreement is more restrictive than permitted by the laws of any jurisdiction where this Agreement may be subject to review and
interpretation, the terms of such restriction, for the purpose only of the operation of such restriction in such jurisdiction, will be the maximum restriction allowed by the laws of such jurisdiction
and such restriction will be deemed to have been revised accordingly herein. 

        12.    Remedies; Survival.    

        (a)   The Employee acknowledges and understands that the provisions of the covenants contained in  Sections 8 and 9 hereof, the violation of which cannot be accurately compensated for in damages
by an action at law, are of crucial importance to the Company, and that the breach or threatened breach of the provisions of this Agreement would cause the Company irreparable harm. In the event of a
breach or threatened breach by the Employee of the provisions of Section 8 or 9 hereof, the Company will be entitled to an injunction restraining the Employee from such breach. Nothing herein
contained will be construed as prohibiting the Company from pursuing any other remedies available for any breach or threatened breach of this Agreement. 

        (b)   Notwithstanding anything contained in this Agreement to the contrary, the provisions of  Sections 8 or 9
hereof will survive the expiration or other termination of this Agreement until,
by their terms, such provisions are no longer operative. 

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        13.    Notices.    Notices and other communications hereunder will be
in writing and will be delivered personally or sent by air courier or first class certified or registered mail, return receipt requested and postage prepaid, addressed as follows: 

	if to the Employee:	 	 
	 	 	Melvin D. Booth

8318 Woodlea Mill Rd

McLean VA 22102
	

and if to the Company:	
 	

Before March 2004:
	

 	
 	

MedImmune, Inc.

35 West Watkins Mill Road

Gaithersburg, Maryland 20878

Attention: Chief Executive Officer
	

 	
 	

After March 2004:
	

 	
 	

MedImmune, Inc.

One MedImmune Way

Gaithersburg, Maryland 20878

Attention: Chief Executive Officer

        All
notices and other communications given to any party hereto in accordance with the provisions of this Agreement will be deemed to have been given on the date of delivery, if
personally delivered; on the business day after the date when sent, if sent by air courier; and on the third business day after the date when sent, if sent by mail, in each case addressed to such
party as provided in this Section 13 or in accordance with the latest unrevoked direction from such party. 

        14.    Binding Agreement; Benefit.    The provisions of this Agreement
will be binding upon, and will inure to the benefit of, the respective heirs, personal representatives, successors and assigns of the parties hereto. 

        15.    Governing Law.    This Agreement will be governed by and
enforceable in accordance with the laws of the State of Maryland applicable to contracts executed and performed within such state, without giving effect to the principles of conflict of laws thereof.
The Company and the Employee agree that any claims concerning the rights and obligations of the parties or any other issue arising under this Agreement shall be brought in the Circuit Court for
Montgomery County or the United States District Court for the District of Maryland, and that such courts shall have exclusive jurisdiction over litigation involving any such claims. The Company and
the Employee agree to submit to the jurisdiction of such courts and that they will not raise lack of personal jurisdiction or inconvenient forum as defenses in any such litigation. 

        16.    Waiver of Breach.    The waiver by either party of a breach of
any provision of this Agreement by the other party must be in writing and will not operate or be construed as a waiver of any subsequent breach by such other party. 

        17.    Entire Agreement; Amendments.    This Agreement (including
Annex A) and the Option Agreements (as amended by this Agreement) contain the entire agreement between the parties with respect to the subject matter hereof and supersede all prior agreements
or understandings among the parties with respect thereof, including, without limitation, the Employment Agreement and any other employment or similar agreement between the Company and the Employee.
This Agreement may be amended only by an agreement in writing signed by the parties hereto. 

        18.    Headings.    The section headings contained in this Agreement
are for reference purposes only and will not affect in any way the meaning or interpretation of this Agreement. 

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        19.    Severability.    Any provision of this Agreement that is
prohibited or unenforceable in any jurisdiction will, as to such jurisdiction, be ineffective to the extent of such prohibition or unenforceability without invalidating the remaining provisions
hereof, and any such prohibition or unenforceability in any jurisdiction will not invalidate or render unenforceable such provision in any other jurisdiction. 

        20.    Assignment.    This Agreement is personal in its nature and the
parties hereto will not, without the consent of the other, assign or transfer this Agreement or any rights or obligations hereunder; provided, that the
provisions hereof (including, without limitation, Sections 8 or 9) will inure to the benefit of, and be binding upon, each successor of the Company, whether by merger, consolidation, transfer
of all or substantially all of its assets or otherwise. 

[Remainder of this page intentionally left blank.]

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        The
parties have duly executed this Agreement effective as of the date first above written. 

	
EMPLOYEE:	
 	
COMPANY:
	

 	
 	
MEDIMMUNE, INC.
	

/s/: Melvin D. Booth

Melvin D. Booth	
 	

By:	
 	

/s/ David M. Mott

David M. Mott
 Chief Executive Officer

7Exhibit 10.58  

AGREEMENT AND GENERAL RELEASE  

        MedImmune, Inc. and Gregory S. Patrick, his heirs, executors, administrators, successors, and assigns (collectively referred to throughout this Agreement
as "Employee"), agree that: 

        1.    Last Day of Employment.    Employee's last day of employment with Employer is
January 16, 2004. 

        2.    Consideration.    In consideration for signing this Agreement and General Release and
compliance with the promises made herein, Employer agrees: 

        a.     to
pay Employee severance payments in the form of semi-monthly payment of the Employee's base salary (as in effect immediately prior to his last day of
employment with Employer) and of the Pro-Rata Bonus Amount for a period of 12 months following the Employee's last day of employment with Employer. Said payments shall commence on
the next regularly scheduled payday after January 16, 2004 and after Employer receives a signed original of the letter attached hereto as Exhibit A. For the purposes of this Agreement,
"Pro-Rata Bonus Amount" shall mean one-twenty-fourth (1/24th) of the average of the three most recent annual cash bonuses paid to the Employee prior to the date of his
termination, including the payment in paragraph "2", section "b" below. Each semi-monthly payment will total an amount of $19,513.92, less lawful deductions. 

        b.     to
pay Employee a one-time payment in the amount of $100,000.00, less lawful deductions, for his final annual cash bonus. 

        c.     to
provide senior executive outplacement services to Employee for a period not to extend beyond twelve (12) months from the last day of employment with Employer. 

        d.     to
pay Employee any remaining accrued vacation, as required by law and MedImmune policy. The amount paid to Employee following Employee's last day of employment shall be
reduced by any vacation taken between the date of this agreement and Employee's last day of employment. 

        e.     to
allow Employee to retain his 401(k) account in accordance with plan terms and IRS guidelines. 

        f.      if
Employee elects to continue medical and/or dental coverage under the MedImmune Plan in accordance with the continuation requirements of COBRA, the Employer shall pay
for the cost of said coverage beginning on the last day of employment and ending on January 31, 2005. Thereafter, Employee shall be entitled to elect to continue such COBRA coverage for the
remainder of the COBRA period, at his own expense. If the COBRA participant elects to participate in a plan other than the MedImmune Plan at any point during the coverage period, participant must
notify MedImmune immediately. 

        3.    No Consideration Absent Execution of this Agreement.    Employee understands and agrees
that he would not receive the monies and/or benefits specified in paragraph "2" above, except for his execution of this Agreement and General Release and the fulfillment of the promises contained
herein. 

        4.    General Release of Claims.    Employee knowingly and voluntarily releases and forever
discharges Employer, its parent corporation, affiliates, subsidiaries, divisions, successors and assigns and the current and former employees, officers, directors and agents thereof (collectively
referred to throughout the remainder of this Agreement as "Employer"), of and from any and all claims, known and unknown, 

1

 

Employee
has or may have against Employer as of the date of execution of this Agreement and General Release, including, but not limited to, any alleged violation of: 

	•
	Title
VII of the Civil Rights Act of 1964, as amended;

	•
	The
Civil Rights Act of 1991;

	•
	Sections
1981 through 1988 of Title 42 of the United States Code, as amended;

	•
	The
Employee Retirement Income Security Act of 1974, as amended ("ERISA");

	•
	The
Immigration Reform and Control Act, as amended;

	•
	The
Americans with Disabilities Act of 1990, as amended;

	•
	The
Age Discrimination in Employment Act of 1967, as amended;

	•
	The
Workers Adjustment and Retraining Notification Act, as amended;

	•
	The
Occupational Safety and Health Act, as amended;

	•
	Maryland
Human Relations Commission Act (MHRCA)—Md. Code Art. 49B §1 et seq.;

	•
	Maryland
Statutory Provision Regarding Retaliation/Discrimination for Filing a Workers' Compensation Claim—Md. Labor & Employment Code §
9-1105;

	•
	Maryland
Equal Pay Law—Md. Labor & Employment Code § 3-301 et seq.;

	•
	Maryland
Adoption Leave Law—Md. Labor & Employment Code §§ 3-801 and 3-802;

	•
	Maryland
Medical Information Bias Law—Md. Labor & Employment Code § 5-604;

	•
	Maryland
Military Leave Law—Md. Public Safety Code sec. 13-705;

	•
	Maryland
law protecting witnesses, jurors and victims who attend court proceedings, Md. Courts and Judicial Proceedings Code §§8-105,
9-205;

	•
	Maryland
Day of Rest Law—Md. Labor & Employment Code § 3-704;

	•
	Maryland
Wage Payment and Work Hour Laws—Md. Labor & Employment Code §§ 3-401 et seq. and 3-501 et seq.;

	•
	Maryland
Occupational Safety & Health Act, as amended—Md. Labor & Employment Code § 5-101 et seq.;

	•
	Any
other federal, state or local civil or human rights law or any other local, state or federal law, regulation or ordinance;

	•
	Any
public policy, contract, tort, or common law; or

	•
	Any
allegation for costs, fees, or other expenses including attorneys' fees incurred in these matters. 

        5.    Affirmations.    

        Employee
affirms that he has not filed, caused to be filed, or presently is a party to any claim, complaint, or action against Employer in any forum or form. 

        Employee
further affirms that he has been paid and/or has received all leave (paid or unpaid), compensation, wages, bonuses, commissions, and/or benefits to which he may be entitled and
that no other leave (paid or unpaid), compensation, wages, bonuses, commissions and/or benefits are due to him, except (1) any already vested benefit under ERISA, and (2) as provided in
this Agreement and General Release. 

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        Employee
furthermore affirms that he has no known workplace injuries or occupational diseases and has been provided and/or has not been denied any leave requested under the Family and
Medical Leave Act. 

        Employee
acknowledges that because of circumstances unique to him including, but not limited to, irreconcilable differences with Employer, he is not qualified to hold any position with
Employer now or in the future and, therefore, shall not apply in the future for employment with Employer. 

        Employee
affirms that he has returned any and all of Employer's property in his possession or control. 

        6.    Confidentiality.    Employee agrees not to disclose any information regarding the
existence or substance of thus Agreement and General Release, except to his spouse, tax advisor, and an attorney with whom Employee chooses to consult regarding his consideration of this Agreement and
General Release. Employee also affirms he has not divulged any proprietary or confidential information of Employer and will not divulge such information at anytime hereafter. 

        7.    Indemnification.        MedImmune, Inc. agrees to indemnify employee
against all liabilities and expenses, including reasonable attorneys' fees, actually or necessarily incurred by or imposed upon him in connection with any proceeding in which he may be made a party,
or in which he may become involved, by reason of his being or having been a director, officer or employee of the corporation, or any settlement thereof, whether or not he is a director, officer or
employee at the time such expenses and liabilities accrue, except in such cases wherein the director, officer or employee is adjudged guilty of will-ful misfeasance or malfeasance or
negligence in the performance of his duties." 

        8.    Governing Law and Interpretation.    This Agreement and General Release shall be
governed and conformed in accordance with the laws of the state in which Employee was employed at the time of his last day of employment without regard to its conflict of laws provision. In the event
the Employee breaches any provision of this Agreement and General Release, Employee and Employer affirm that either may institute an action to specifically enforce any term or terms of this Agreement
and General Release. Should any provision of this Agreement and General Release be declared illegal or unenforceable by any court of competent jurisdiction and cannot be modified to be enforceable,
excluding the general release language, such provision shall immediately become null and void, leaving the remainder of this Agreement and General Release in full force and effect. 

        9.    Nonadmission of Wrongdoing.    The parties agree that neither this Agreement and General
Release nor the furnishing of the consideration for this Release shall be deemed or construed at anytime for any purpose as an admission by either party of any liability or unlawful conduct of any
kind. 

        10.    Amendment.    This Agreement and General Release may not be modified, altered or
changed except upon express written consent of both parties wherein specific reference is made to this Agreement and General Release. 

        11.    Revocation.    Employee may revoke this Agreement and General Release for a period of
seven (7) calendar days following the day he executes this Agreement and General Release. Any revocation within this period must be submitted, in writing, to Pamela J. Lupien and state, "I
hereby revoke my acceptance of our Agreement and General Release." The revocation must be personally delivered to Pamela J. Lupien or her designee, or mailed to Pamela J. Lupien and postmarked within
seven (7) calendar days of execution of this Agreement and General Release. This Agreement and General Release shall not become effective or enforceable until the revocation period has expired.
If the last day of the revocation period is a Saturday, Sunday, or legal holiday in the state in which Employee was employed at the time of his last day of employment, then the revocation period shall
not expire until the next following day which is not a Saturday, Sunday, or legal holiday. 

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        12.    Entire Agreement.    This Agreement and General Release sets forth the entire agreement
between the parties hereto, and fully supersedes any prior agreements or understandings between the parties, except
the Employee Proprietary Information and Invention Agreement. Employee acknowledges that he has not relied on any representations, promises, or agreements of any kind made to him in connection with
his decision to accept this Agreement and General Release, except for those set forth in this Agreement and General Release. 

        EMPLOYEE HAS BEEN ADVISED THAT HE HAS UP TO TWENTY-ONE (21) CALENDAR DAYS TO REVIEW THIS AGREEMENT AND GENERAL RELEASE AND HAS BEEN ADVISED IN
WRITING TO CONSULT WITH AN ATTORNEY PRIOR TO EXECUTION OF THIS AGREEMENT AND GENERAL RELEASE.

        EMPLOYEE AGREES THAT ANY MODIFICATIONS, MATERIAL OR OTHERWISE, MADE TO THIS AGREEMENT AND GENERAL RELEASE DO NOT RESTART OR AFFECT IN ANY MANNER THE ORIGINAL
TWENTY-ONE (21) CALENDAR DAY CONSIDERATION PERIOD.

        HAVING ELECTED TO EXECUTE THIS AGREEMENT AND GENERAL RELEASE, TO FULFILL THE PROMISES AND TO RECEIVE THE SUMS AND BENEFITS IN PARAGRAPH "2" ABOVE, EMPLOYEE FREELY
AND KNOWINGLY, AND AFTER DUE CONSIDERATION, ENTERS INTO THIS AGREEMENT AND GENERAL RELEASE INTENDING TO WAIVE, SETTLE AND RELEASE ALL CLAIMS HE HAS OR MIGHT HAVE AGAINST
EMPLOYER.

        IN
WITNESS WHEREOF, the parties hereto knowingly and voluntarily executed this Agreement and General Release as of the date set forth below: 

	

/s/ GREGORY S. PATRICK
Gregory S. Patrick	
 	

 
	

Date:	
 	

December 31, 2003	
 	

 
	
MedImmune, Inc.	
 	

 
	

By:	
 	

/s/ PAMELA J. LUPIEN
 Pamela J. Lupien	
 	

 
	

Date:	
 	

December 31, 2003	
 	

 
	

By:	
 	

/s/ DAVID M. MOTT
 David M. Mott	
 	

 
	

Date:	
 	

January 5, 2004	
 	

 

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