Document:

Execution

 

STOCK PURCHASE AGREEMENT

 

by and between

 

Interleukin Genetics, Inc.

 

and

 

Delta Dental Plan of Michigan, Inc.

 

June 29, 2012

 

    	 

    	 

    

 

Table
of Contents

 

	 	 	Page
	 	 	 
	1.	PURCHASE AND SALE	1
	 	 	 
	 	(a)	Purchase of Shares	1
	 	 	 
	2.	THE CLOSING	1
	 	 	 
	 	(a)	Closing Date	1
	 	 	 	 
	 	(b)	Form of Payment	1
	 	 	 	 
	 	(c)	Conditions to the Purchaser’s Obligation to Purchase the Shares	2
	 	 	 	 
	 	(d)	Conditions to the Company’s Obligation to Issue and Sell the Shares	4
	 	 	 
	3.	REPRESENTATIONS AND WARRANTIES OF THE COMPANY	5
	 	 	 
	 	(a)	Organization and Qualification	5
	 	 	 	 
	 	(b)	Subsidiaries	5
	 	 	 	 
	 	(c)	Authorization; Enforcement; Validity	5
	 	 	 	 
	 	(d)	Capitalization	6
	 	 	 	 
	 	(e)	Issuance of Shares	6
	 	 	 	 
	 	(f)	No Conflicts	7
	 	 	 	 
	 	(g)	No Violation or Default	7
	 	 	 	 
	 	(h)	SEC Documents	7
	 	 	 	 
	 	(i)	Financial Statements	8
	 	 	 	 
	 	(j)	No Material Adverse Change	8
	 	 	 	 
	 	(k)	Independent Accountants	8
	 	 	 	 
	 	(l)	Title to Intellectual Property	8
	 	 	 	 
	 	(m)	Licenses and Permits	9
	 	 	 	 
	 	(n)	Environmental Matters	9
	 	 	 	 
	 	(o)	Tax Matters	9
	 	 	 	 
	 	(p)	Internal Control over Financial Reporting	10
	 	 	 	 
	 	(q)	Disclosure Controls and Procedures	10
	 	 	 	 
	 	(r)	Sarbanes-Oxley Compliance	10

 

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Table
of Contents

(continued)

 

	 	Page
	 	 
	 	(s)	Absence of Litigation	10
	 	 	 	 
	 	(t)	Investment Company Act	10
	 	 	 	 
	 	(u)	Regulation.	10
	 	 	 
	4.	PURCHASER’S REPRESENTATIONS AND WARRANTIES	11
	 	 	 
	 	(a)	Transfer or Resale	11
	 	 	 	 
	 	(b)	Investment Purpose	11
	 	 	 	 
	 	(c)	General Solicitation	11
	 	 	 	 
	 	(d)	Information	11
	 	 	 	 
	 	(e)	Reliance on Exemptions	11
	 	 	 	 
	 	(f)	No Governmental Review	11
	 	 	 	 
	 	(g)	Authorization; Enforcement; Validity	12
	 	 	 	 
	 	(h)	No Conflicts	12
	 	 	 
	5.	RESTRICTIONS ON TRANSFER; OWNERSHIP OF SHARES	12
	 	 	 
	 	(a)	Resales	12
	 	 	 	 
	 	(b)	Rule 144	12
	 	 	 	 
	 	(c)	Legends	12
	 	 	 	 
	 	(d)	Agreement to be Bound	13
	 	 	 
	6.	BOARD REPRESENTATIVE	13
	 	 	 
	 	(a)	Series B Director	13
	 	 	 	 
	 	(b)	Restrictions on Series B Designee	13
	 	 	 	 
	 	(c)	Board of Directors	14
	 	 	 
	7.	CORPORATE OPPORTUNITY POLICY	14
	 	 	 
	 	(a)	Section 6.8 of Pyxis SPA	14
	 	 	 	 
	 	(b)	Series B Director	14
	 	 	 
	8.	PUBLIC STATEMENTS	16
	 	 	 
	9.	MISCELLANEOUS	16
	 	 	 
	 	(a)	Governing Law	16

 

    	-ii-

    	 

    

 

Table
of Contents

(continued)

 

	 	 	 	Page
	 	 	 	 
	 	(b)	Entire Agreement	17
	 	 	 	 
	 	(c)	Amendments and Waivers	17
	 	 	 	 
	 	(d)	Notices	17
	 	 	 	 
	 	(e)	No Strict Construction	18
	 	 	 	 
	 	(f)	Further Assurances	18
	 	 	 	 
	 	(g)	Severability	18
	 	 	 	 
	 	(h)	Successors and Assigns	18
	 	 	 	 
	 	(i)	Survival	18
	 	 	 	 
	 	(j)	Headings	18
	 	 	 	 
	 	(k)	Counterparts	18
	 
	EXHIBITS
	Exhibit A – Series A-1 and Series B Convertible Preferred Stock Certificate of Designation
	 
	Exhibit B – Series B Designee Director Indemnity Agreement
	 
	Exhibit C – Third Amendment to Pyxis Stock Purchase Agreement
	 
	Exhibit D – Registration Rights Agreement

  

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STOCK
PURCHASE AGREEMENT

 

This Stock Purchase Agreement (this “Agreement”)
dated as of June 29, 2012 is made by and between Interleukin Genetics, Inc., a Delaware corporation, (the “Company”),
and Delta Dental Plan of Michigan, Inc., a Michigan nonprofit corporation (the “Purchaser”).

 

RECITALS

 

In accordance with the terms and conditions
of this Agreement and pursuant to exemptions from registration under the Securities Act of 1933, as amended (the “Securities
Act”), the Company has agreed to issue and sell, and the Purchaser has agreed to purchase a number of shares of the Company’s
Series B Convertible Preferred Stock, par value $0.001 per share (the “Preferred Stock”), having the rights,
privileges, preferences and restrictions set forth in the form of Certificate of Designations, Rights and Preferences attached
hereto as Exhibit  A (the “Certificate of Designation”), and convertible in accordance with the
terms thereof into shares of the Company’s common stock, par value $0.001 per share (the “Common Stock”),
of the Company.

 

NOW THEREFORE, in consideration of the promises
and the mutual covenants contained herein and other good and valuable consideration, the receipt and sufficiency of which are hereby
acknowledged, the Company and the Purchaser hereby agree as follows:

 

1.         PURCHASE AND SALE

 

(a)       Authorization of Shares.
The Company has authorized (i) the sale and issuance to Purchaser of the Shares (defined below) and (ii) the issuance
of such shares of Common Shares (defined below) to be issued upon conversion of the Shares. The Shares and the Common Shares have
the rights, preferences, privileges and restrictions set forth in the Certificate of Designation.

 

(b)       Purchase of Shares.
At the Closing (as defined below), the Company shall issue and sell to the Purchaser, and the Purchaser shall purchase from the
Company, upon the terms and subject to the conditions set forth herein 500,000 shares of Preferred Stock (the “Shares”)
for an aggregate purchase price of $3,000,000 (the “Purchase Price”), based on a purchase price per share of
$6.00 (the “Per Share Purchase Price”).

 

2.         THE CLOSING

 

(a)        Closing Date. The date
and time of the closing of the purchase and sale of the Shares (the “Closing”) shall occur on June 29, 2012
at 2:00 p.m. Boston time, at the offices of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C., One Financial Center, Boston,
Massachusetts, 02111 (subject to the satisfaction or waiver of the conditions set forth in Subsections (c) and (d) of this Section
2), or at such other location, date and time as may be agreed upon between the Company and the Purchaser (the “Closing
Date”).

 

(b)       Form of Payment. On
the Closing Date, the Purchaser shall pay the Company the Purchase Price for the Shares to be issued and sold to the Purchaser,
by wire transfer of immediately available funds in accordance with the Company’s written wire instructions previously provided
to the Purchaser, and the Company shall deliver to the Purchaser the original certificate or certificates representing the Shares,
registered in the name of the Purchaser.

 

    	 

    	 

    

 

(c)        Conditions to the Purchaser’s
Obligation to Purchase the Shares. The Purchaser’s obligation to purchase the Shares shall be subject to the satisfaction,
on or before the Closing Date, of each of the following conditions, provided that these conditions are for the Purchaser’s
sole benefit and may be waived by the Purchaser at any time in its sole discretion:

 

		(i)	receipt of a copy of this Agreement executed by the Company;

 

		(ii)	an Exchange Agreement by and between the Company and Pyxis Innovations Inc. (the “Series A Stockholder”),
pursuant to which the shares of Series A convertible preferred stock of the Company held by the Series A Stockholder shall be exchanged
for shares of Series A-1 convertible preferred stock (the “Series A Preferred Stock”), shall have been executed
by each party thereto (the “Exchange Agreement”);

 

		(iii)	a Certificate of Elimination of the Series A Preferred Stock shall have been filed with the Secretary of State of the State
of Delaware;

 

		(iv)	the Certificate of Designation shall have been filed with the Secretary of State of the State of Delaware;

 

		(v)	receipt of one or more certificates representing the Shares;

 

		(vi)	Catherine Ehrenberger, a designee of the Series A Stockholder to the Board of Directors of the Company (the “Board”),
shall have resigned from the Board and a copy of the written resignation shall have been delivered to the Purchaser;

 

		(vii)	(A) all actions required by the Board to elect an individual designated by the Purchaser (the “Series B Designee”)
to the Board to serve from and after the Closing Date until a successor is duly elected and qualified, shall have been taken; (B) 
the Company shall have taken all necessary action for such Series B Designee to be fully covered by the Company’s directors’
and officers’ liability insurance in an amount no less than the directors designated by the holders of the Series A
Preferred Stock; and (C) the Company shall have entered into a director indemnity agreement with such Series B Designee
in substantially the form attached as Exhibit B;

 

		(viii)	all consents, approvals and waivers, including consents, approvals and waivers of the Series A Stockholder (the “Series
A Approvals”), required for the consummation of the transactions contemplated hereby shall have been obtained;

 

		(ix)	the Common Shares issuable upon conversion of the Shares shall have been duly authorized and reserved for issuance upon such
conversion;

 

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		(x)	the Company shall have delivered to Purchasers a Compliance Certificate, executed by the Chief Executive Officer of the Company,
dated as of the Closing Date, to the effect that the conditions specified in subsections (ii), (iii), (iv), (vi), (vii), (ix),
(xii), (xiii), (xiv), and (xvi) of this Section 2(c) have been satisfied;

 

		(xi)	the Company shall have delivered a certificate of its Secretary certifying as to (A) the resolutions of the Board of Directors
approving this Agreement and the transactions contemplated thereby, including the actions required by the Company pursuant to this
Section 2(c); (B) true and correct copies of the Certificate of Elimination and the Certificate of Designation referenced
in (iii) and (iv) above as filed with the Secretary of State of the State of Delaware; and (C) good standing certificates
(including tax good standing) with respect to the Company from the applicable authority(ies) in Delaware and any other jurisdiction
in which the Company is qualified to do business dated a recent date before Closing;

 

		(xii)	the representations and warranties of the Company in this Agreement shall be true, correct and complete as of the Closing Date
(except for representations and warranties that speak as of a specific date, which shall be true, correct and complete as of such
date) and the Company shall have performed, satisfied and complied in all material respects with the covenants, agreements and
conditions required by this Agreement to be performed, satisfied or complied with by the Company at or prior to the Closing;

 

		(xiii)	no temporary restraining order, preliminary or permanent injunction or other order or decree, and no other legal restraint
or prohibition, shall exist which questions the validity of this Agreement or the right of the Company or the Purchaser, as the
case may be, to enter into this Agreement or prevents or could reasonably be expected to prevent the consummation of the transactions
contemplated by this Agreement, nor shall any proceeding have been commenced or threatened with respect to the foregoing;

 

		(xiv)	Section 6.8 of the Pyxis SPA (as defined in Section 6(c) below) shall have been amended as set forth in Exhibit C;
and the Board shall have adopted Section 6.8, as amended as set forth in Exhibit C, and Section 7(b) of this
Agreement, as the Company's corporate opportunity policy in accordance with Section 122(17) of the Delaware General Corporation
Law;

 

		(xv)	the Purchaser shall have received from the Series A Stockholder a certificate of its Secretary certifying as to the resolutions
of its Board of Directors approving (A) the Exchange Agreement; (B) the filing of the Certificate of Elimination; (C) the
Series A Approvals (including a certified copy of resolutions of the Board of Directors of Pyxis Innovations Inc. authorizing
such Series A Approvals); and (D) the amendments to the Pyxis SPA;

 

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		(xvi)	the Company shall have executed and delivered the Registration Rights Agreement in substantially the form attached as Exhibit D;
and

 

		(xvii)	receipt of such other information, certificates and documents as the Purchaser may reasonably request.

 

(d)        Conditions to the Company’s
Obligation to Issue and Sell the Shares. The Company’s obligation to issue and sell the Shares shall be subject to the
satisfaction, on or before the Closing Date, of each of the following conditions, provided that these conditions are for the Company’s
sole benefit and may be waived by the Company at any time in its sole discretion:

 

		(i)	receipt of a copy of this Agreement executed by the Purchaser;

 

		(ii)	receipt of the Purchase Price;

 

		(iii)	the Exchange Agreement shall have been executed by the Series A Stockholder;

 

		(iv)	the representations and warranties of the Purchaser in this Agreement shall be true, correct and complete as of the date of
this Agreement and the Closing Date (except for representations and warranties that speak as of a specific date, which shall be
true, correct and complete as of such date) and the Purchaser shall have performed, satisfied and complied with in all material
respects the covenants, agreements and conditions of the Purchaser to be performed, satisfied or complied with by it under this
Agreement at or prior to the Closing;

 

		(v)	no temporary restraining order, preliminary or permanent injunction or other order or decree, and no other legal restraint
or prohibition shall exist which questions the validity of this Agreement or the right of the Company or the Purchaser, as the
case may be, to enter into this Agreement or prevents or could reasonably be expected to prevent the consummation of the transactions
contemplated by this Agreement, nor shall any proceeding have been commenced or threatened with respect to the foregoing;

 

		(vi)	the Purchaser shall have delivered to the Company a Compliance Certificate, executed by the Chief Executive Officer of the
Purchaser, dated as of the Closing Date, to the effect that the conditions specified in subsection (iv) of this Section 2(d)
have been satisfied; and

 

		(vii)	receipt of such other information, certificates and documents as the Company may reasonably request.

 

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3.        REPRESENTATIONS AND WARRANTIES
OF THE COMPANY

 

The Company represents and warrants to the
Purchaser, subject to such exceptions as are set forth in the SEC Documents (as defined below), as follows:

 

(a)       Organization and Qualification.
The Company is a corporation, duly organized, validly existing and in good standing under the laws of the State of Delaware, and
has the requisite corporate power and authority to own its properties and to carry on its business as now being conducted and as
described in the SEC Documents. Copies of the Company’s Certificate of Incorporation, as amended (including the Certificate
of Designation for the Series A Preferred Stock, the “Charter”) and Amended and Restated Bylaws of the Company,
as amended (the “Bylaws”), and in each case, all amendments thereto, have been filed as exhibits to the Company’s
SEC Documents and have not been further modified, and except as required by the transactions contemplated hereby, the Company has
no present intention to modify the Charter and Bylaws. The Company is duly qualified as a foreign corporation to do business, and
is in good standing, in every jurisdiction in which its ownership of property or the nature of the business conducted and proposed
to be conducted by it makes such qualification necessary, except where the failure to be so qualified or in good standing would
not, individually or in the aggregate, have or reasonably be expected to result in a material adverse effect on the condition (financial
or otherwise), prospects, earnings, assets, results of operations, business or properties of the Company, whether or not arising
from transactions in the ordinary course of business (“Material Adverse Effect”).

 

(b)       Subsidiaries. The Company
has no subsidiaries.

 

(c)       Authorization; Enforcement;
Validity. The Company has the requisite corporate power and authority to enter into and perform its obligations under this
Agreement and to issue the Shares in accordance with the terms hereof. The execution and delivery of this Agreement by the Company
and the consummation and performance by the Company of the transactions contemplated hereby, including, without limitation, the
issuance of the Shares and of the shares of Common Stock issuable upon conversion of the Shares (the “Common Shares”
and together with the Shares, the “Securities”), have been duly authorized by all requisite corporate action,
including all actions required by the Series A Stockholder. This Agreement has been duly executed and delivered by the Company.
This Agreement constitutes the valid and binding obligation of the Company enforceable against the Company in accordance with its
terms, except as such enforceability may be limited by general principles of equity or applicable bankruptcy, insolvency, reorganization,
moratorium, liquidation or similar laws relating to, or affecting generally, the enforcement of creditors’ rights and remedies.

 

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(d)       Capitalization. As
of June 29, 2012, the authorized capital stock of the Company consists of (i) 100,000,000 shares of Common Stock and (ii) 6,000,000
shares of preferred stock, $0.001 par value per share, 5,000,000 of which have been designated as Series A Preferred Stock. As
set forth in the definitive proxy statement filed with the U.S. Securities and Exchange Commission (the “SEC”)
on June 22, 2012, the Company is seeking to increase the number of authorized shares of Common Stock to 150,000,000, subject to
approval at the Company’s 2012 Annual Meeting of Stockholders. As of June 29, 2012, (i) 36,761,864 shares of Common Stock
are issued and outstanding; (ii) 5,000,000 shares of Series A Preferred Stock are issued or outstanding (which are convertible
into 28,160,200 shares of Common Stock); (iii) 2,228,067 shares of Common Stock are duly reserved for future issuance pursuant
to outstanding stock options; (iv) 2,150,000 shares of Common Stock are duly reserved for future issuance pursuant to outstanding
warrants; (v) 2,521,222 shares of Common Stock are duly reserved for future issuance pursuant to outstanding convertible debt;
(vi) 2,212,313 shares of Common Stock are duly reserved for future issuance pursuant to the Company’s stock plans; and
(vii)  no shares of Common Stock are duly reserved for future issuance pursuant to the Company’s employee stock purchase
plan (not including 750,000 shares reserved for issuance pursuant to the employee stock purchase plan that is subject to approval
at the Company’s 2012 Annual Meeting of Stockholders). All of the issued shares of capital stock of the Company have been
duly and validly authorized and issued, are fully paid and non-assessable, and have been issued in compliance with federal and
state securities laws. The Company has not issued any capital stock since June 29, 2012 other than pursuant to the exercise of
stock options under the Company's stock option plans, the issuance of shares of Common Stock to employees pursuant to the Company's
employee stock purchase plan (such issuances and any such stock options, whenever issued or granted, being collectively “Employee
Equity Transactions”), pursuant to the conversion or exercise of outstanding securities that are convertible into or
exercisable for Common Stock, or pursuant to publicly disclosed equity financings. Except for Employee Equity Transactions and
as set forth in the SEC Documents, (i) no shares of the Company’s capital stock are subject to preemptive rights or any other
similar rights or any liens or encumbrances; (ii) there are no outstanding options, warrants, rights to subscribe to, calls or
commitments relating to, or securities or rights convertible into, any shares of capital stock of the Company, or contracts, commitments,
understandings or arrangements by which the Company is or may become bound to issue additional shares of capital stock of the Company
or options, warrants, rights to subscribe to, calls or commitments relating to, or securities or rights convertible into, any shares
of capital stock of the Company. The Company has no knowledge of any voting agreements, buy-sell agreements, option or right of
first purchase agreements or other agreements of any kind among any of the security holders of the Company relating to the securities
of the Company held by them. Other than pursuant to the Registration Rights Agreement to be entered into by and between the Company
and the Purchaser, and except as set forth in (i) that certain Registration Rights Agreement dated August 9, 2002, (ii) that
certain Registration Rights Agreement between the Company and the Series A Stockholder dated March 5, 2003, the Company has
not granted any person the right to require the Company to register any securities of the Company under the 1933 Act, whether on
a demand basis or in connection with the registration of securities of the Company for its own account or for the account of any
other Person.

 

(e)        Issuance of Shares.
The Common Shares have been duly and validly reserved for issuance. The Shares and the Common Shares are duly authorized and, upon
issuance in accordance with the terms hereof and the Certificate of Designation, will be (A) validly issued, fully paid and non-assessable
and (B) free from all taxes, liens and charges in the United States of America with respect to the issuance thereof, other than
any liens or encumbrances created by or imposed by the Purchaser, and not subject to preemptive rights or other similar rights
of stockholders of the Company, except for rights of the Series A Stockholder that have been waived. Except for the Series A Approvals
and the filing of any notice prior or subsequent to the Closing that may be required under applicable state and/or federal securities
laws (or comparable laws of any other jurisdiction), no authorization, consent, approval, license, exemption of or filing or registration
with any court or governmental department, commission, board, bureau, agency, instrumentality or other third party, is or will
be necessary for, or in connection with, the execution and delivery by the Company of this Agreement, for the offer, issue, sale,
execution or delivery of the Shares, or for the performance by the Company of its obligations under this Agreement. The Company
has reserved from its duly authorized capital stock the Shares and the Common Shares issuable upon conversion of the Shares.

 

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(f)        No Conflicts. Subject
to the Series A Approvals, the execution, delivery and performance of this Agreement by the Company and the consummation by the
Company of the transactions contemplated hereby do not and will not (i) result in a breach or violation of the Company’s
Charter or Bylaws; (ii) conflict with, or constitute a default (or an event which with notice or lapse of time or both would become
a default) under any agreement, indenture or instrument to which the Company is a party; (iii) result in a violation of any statute,
law, rule, regulation, order, judgment or decree applicable to the Company; or (iv) result in the imposition of a mortgage, pledge,
security interest, encumbrance, charge or other lien on any asset of the Company.

 

(g)        No Violation or Default.
The Company is not (i) in violation of its Charter or Bylaws; (ii) in default (or subject to an event which with notice or lapse
of time or both would become a default) under any agreement, indenture or instrument to which the Company is a party; or (iii)
in violation of any law, rule, regulation, order, judgment or decree applicable to the Company; except for such violations or defaults,
as described in clauses (ii) or (iii) of this sentence as are set forth in the SEC Documents or as would not, individually or in
the aggregate, have or result in a Material Adverse Effect.

 

(h)        SEC Documents. The
Company has filed all reports, schedules, forms, statements, exhibits (including certifications of the Company’s principal
executive and financial officers pursuant to Section 302 and 906 of Sarbanes-Oxley (as defined below) and other documents required
to be filed by it with the SEC pursuant to the reporting requirements of the Securities Exchange Act of 1934, as amended (the “Exchange
Act”), for the twelve (12) months preceding the date hereof (all of the foregoing filed prior to or on the date hereof,
or prior to the Closing Date, and all exhibits included therein and financial statements and schedules thereto and documents incorporated
by reference therein being referred to in this Agreement as the “SEC Documents”). As of the date of filing of
each such SEC Document, such SEC Document, as it may have been subsequently amended by filings made by the Company with the SEC
prior to the date hereof, complied in all material respects with the requirements of the Exchange Act and the rules and regulations
of the SEC promulgated thereunder applicable to such SEC Document. None of the SEC Documents, as of the date filed and as they
may have been subsequently amended by filings made by the Company with the SEC prior to the date hereof, contained any untrue statement
of a material fact or omitted to state a material fact required to be stated therein or necessary in order to make the statements
therein, in the light of the circumstances under which they were made, not misleading.

 

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(i)        Financial Statements.
The financial statements and the related notes thereto of the Company included or incorporated by reference in the SEC Documents
comply in all material respects with the applicable requirements of the Exchange Act, as applicable, and present fairly and accurately
in all material respect the financial position of the Company as of the dates indicated and the results of operations and the changes
in cash flows for the periods specified. Such financial statements have been prepared in conformity with United States generally
accepted accounting principles (“GAAP”) applied on a consistent basis throughout the periods covered thereby,
except as specifically stated therein, and the supporting schedules included or incorporated by reference in the SEC Documents
present fairly the information required to be stated therein. The Company does not have any material liability or obligation of
any nature, whether or not accrued, contingent or otherwise that would be required by GAAP to be disclosed on a balance sheet of
the Company or in the notes thereto. The Company has not created any entities or entered into any transactions or created any liabilities
or obligations of any nature, whether or not accrued, contingent or otherwise, for the purpose of avoiding disclosure required
by GAAP.

 

(j)        No Material Adverse Change.
Since the date of the most recent financial statements of the Company included or incorporated by reference in the SEC Documents,
except as disclosed in the SEC Documents and as contemplated by this Agreement, (i) there has not been any change in the capital
stock (other than pursuant to Employee Equity Transactions, pursuant to the conversion or exercise of outstanding securities that
are convertible into or exercisable for Common Stock, or pursuant to publicly disclosed equity or debt financings) or long-term
debt of the Company, or any dividend or distribution of any kind declared, set aside for payment, paid or made by the Company on
any class of capital stock, or any material adverse change in or affecting the assets, results of operations, business, properties,
management, financial condition or operations of the Company taken as a whole; (ii) the Company has not entered into any transaction
or agreement that is material to the Company taken as a whole or incurred any liability or obligation, direct or contingent, that
is material to the Company and, except as contemplated by this agreement, has not made any material change or amendment to a material
contract or arrangement by which the Company or any of its assets or properties is bound or subject; and (iii) the Company has
not sustained any material loss or interference with its business from fire, explosion, flood or other calamity, whether or not
covered by insurance, or from any labor disturbance or dispute or any action, order or decree of any court or arbitrator or governmental
or regulatory authority.

 

(k)        Independent Accountants.
Grant Thornton LLP, who have certified certain financial statements of the Company, are, to the Company’s knowledge, independent
registered public accountants with respect to the Company as required by the Securities Act.

 

(l)        Title to Intellectual Property.
The Company owns or possesses adequate rights to use all patents, patent applications, trademarks, service marks, trade names,
trademark registrations, service mark registrations, copyrights, licenses and know-how (including trade secrets and other unpatented
or unpatentable proprietary or confidential compounds, genes, information, systems or procedures) (collectively, the “Intellectual
Property”), used in or necessary for the conduct of the Company’s current business. Except as set forth in the
SEC Documents, (i) there are no rights of third parties to any such Intellectual Property except through licensing or cross-licensing
agreements; (ii) to the Company’s knowledge, there is no infringement by third parties of any granted patents that are
necessary and material to the Company’s business as it is presently being conducted; (iii) there is no pending or, to
the Company’s knowledge, threatened action, suit, proceeding or claim by others challenging the Company’s ownership
or licensing rights in or to any such Intellectual Property; (iv) there is no pending or, to the Company’s knowledge,
threatened action, suit, proceeding or claim by others challenging the validity or scope of any such Intellectual Property, other
than ordinary patent, trademark, service mark and copyright prosecution; (v) there is no pending or, to the Company’s
knowledge, threatened action, suit, proceeding or claim by others that the Company infringes or otherwise violates any patent,
trademark, copyright, trade secret or other proprietary rights of others, and the Company is unaware of any reasonable basis for
any such claim; (vi) the Company does not believe it is or will be necessary to utilize any inventions, trade secrets or proprietary
information of any of its employees made prior to their employment by the Company; and (vii) the Company has taken all steps
reasonably determined by the Company to be necessary to perfect its ownership of and interest in such Intellectual Property.

 

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(m)       Licenses and Permits.
The Company possesses all licenses, certificates, permits and other authorizations issued by, and have made all declarations and
filings with, the appropriate federal, state, local or foreign governmental or regulatory authorities, that are necessary for the
ownership or lease of its properties or the conduct of its business as described in the SEC Documents. The Company has not received
notice of any revocation or modification of any such license, certificate, permit or authorization or has any reason to believe
that any such license, certificate, permit or authorization will not be renewed in the ordinary course.

 

(n)        Environmental Matters.
The Company is in compliance with all foreign, federal, state and local rules, laws and regulations relating to the use, treatment,
storage and disposal of hazardous or toxic substances or waste and protection of health and safety or the environment which are
applicable to their businesses. To the Company’s knowledge, there has been no storage, generation, transportation, handling,
treatment, disposal, discharge, emission, or other release of any kind of toxic or other wastes or other hazardous substances by,
due to, or caused by the Company (or, to the Company’s knowledge, any other entity for whose acts or omissions the Company
is or may be liable) upon any of the property now or previously owned or leased by the Company, or upon any other property, in
violation of any statute or any ordinance, rule, regulation, order, judgment, decree or permit or which would, under any statute
or any ordinance, rule (including rule of common law), regulation, order, judgment, decree or permit, give rise to any liability.
There has been no disposal, discharge, emission or other release of any kind onto such property or into the environment surrounding
such property of any toxic or other wastes or other hazardous substances with respect to which the Company has knowledge.

 

(o)        Tax Matters. The Company
(i) has timely filed all necessary federal, state and foreign income and franchise tax returns or has requested extensions thereof,
(ii) has paid all federal state, local and foreign taxes due and payable for which it is liable, except for any such taxes currently
being contested in good faith, and (iii) does not have any tax deficiency or claims outstanding or assessed or, to the best of
the Company’s knowledge, proposed against it. All material taxes and other assessments and levies that the Company is required
to withhold or to collect for payment have been duly withheld and collected and paid to the proper government entity or third party
when due. There are no tax liens or claims pending or, to the Company’s knowledge, threatened against the Company or any
of its respective assets or property. Except as set forth in “Note 4 – Summary of Significant Accounting Policies –
Income Taxes,” to the Company’s financial statements set forth in its Annual Report on Form 10-K for the year ended
December 31, 2011, there are no outstanding tax sharing agreements or other such arrangements between the Company and any other
Person.

 

    	-9-

    	 

    

 

(p)       Internal Control over Financial
Reporting. The Company maintains a system of internal control over financial reporting (as such is defined in Rule 13a-15(f)
of the Exchange Act) that complies with the requirements of the Exchange Act and has been designed by the Company’s principal
executive officer and principal financial officer, or under their supervision, to provide reasonable assurance regarding the reliability
of financial reporting and the preparation of financial statements for external purposes in accordance with GAAP. The Company does
not have any material weaknesses in its internal control over financial reporting. Since the date of the latest audited financial
statements included in the SEC Documents, there has been no change in the Company’s internal control over financial reporting
that has materially affected, or is reasonably likely to materially affect, the Company’s internal control over financial
reporting.

 

(q)       Disclosure Controls and
Procedures. The Company maintains disclosure controls and procedures (as such term is defined in Rule 13a-15(e) of the Exchange
Act) that comply with the requirements of the Exchange Act. Such disclosure controls and procedures have been designed to ensure
that material information relating to the Company is accumulated and communicated to the Company’s management, including
the Company’s principal executive officer and principal financial officer, by others within those entities.

 

(r)        Sarbanes-Oxley Compliance.
The Company and the Company’s directors and officers, in their capacities as such, are in compliance with any provision of
the Sarbanes-Oxley Act of 2002 and the rules and regulations promulgated in connection therewith (“Sarbanes-Oxley”),
including Section 402 related to loans and Sections 302 and 906 related to certifications, and neither the Company nor any of its
officers has received notice from any governmental entity questioning or challenging the accuracy, completeness, content, form
or manner of filing or submission of such certifications.

 

(s)        Absence of Litigation.
There is no action, suit, proceeding, inquiry or investigation before or by any court, public board, government agency, self-regulatory
organization or body pending or, to the knowledge of the Company, threatened in writing against the Company which (i) adversely
affects or challenges the legality, validity or enforceability of this Agreement or the Securities or (ii) would reasonably be
expected to result in a Material Adverse Effect.

 

(t)        Investment Company Act.
The Company is not, nor, after giving effect to the sale of the Shares and the application of the proceeds therefrom, will it become,
an “investment company” within the meaning of the Investment Company Act of 1940, as amended, and the rules and regulations
of the SEC thereunder.

 

(u)        Regulation. Assuming
the accuracy of the representations and warranties made by the Purchasers in Section 4 of this Agreement, the offer, issuance,
sale and delivery of the Shares and the Common Shares are or will be exempt from the registration requirements of the 1933 Act
and the qualification or registration provisions of applicable state securities laws. Neither the Company nor its authorized agents
have taken or will take any action that would cause the loss of such exemption. Neither the Company nor any person acting on its
behalf has conducted any general solicitation or general advertising (as those terms are used in Regulation D) in connection
with the offer or sale of any of the Preferred Stock. Neither the Company nor any of its affiliates, nor any person acting on its
or their behalf has, directly or indirectly, made any offers or sales of any security or solicited any offers to buy any security,
under circumstances that would adversely affect reliance by the Company on Section 4(2) of the 1933 Act for the exemption
from registration for the contemplated transactions under this Agreement or would require registration of the Shares or the Common
Shares under the 1933 Act.

 

    	-10-

    	 

    

 

4.         PURCHASER’S REPRESENTATIONS
AND WARRANTIES

 

The Purchaser represents and warrants to
the Company that:

 

(a)       Transfer or Resale.
The Purchaser understands that the Securities have not been registered under the Securities Act or any state securities laws, and
may not be offered for sale, sold, assigned or transferred without registration under the Securities Act or an exemption therefrom
and that, in the absence of an effective registration statement under the Securities Act, such Securities may only be sold under
certain circumstances as set forth in the Securities Act.

 

(b)       Investment Purpose.
The Purchaser is acquiring the Securities for its own account for investment only and not with a view towards, or for resale in
connection with, the public sale or distribution thereof. The Purchaser does not have any agreement or understanding, directly
or indirectly, with any person to distribute any of the Securities.

 

(c)      General Solicitation.
The Purchaser is not purchasing the Securities as a result of any advertisement, article, notice or other communication regarding
the Securities published in any newspaper, magazine or similar media or broadcast over television or radio or presented at any
seminar or any other general solicitation or general advertisement.

 

(d)       Information. The Purchaser
(directly or through its advisors, if any) (i) has been furnished with or has had full access to all of the publicly available
information that it considers necessary or appropriate for deciding whether to purchase the Securities, (ii) has had an opportunity
to ask questions and receive answers from the Company regarding the terms and conditions of the offering of the Securities, (iii)
can bear the economic risk of a total loss of its investment in the Securities and (iv) has such knowledge and experience in business
and financial matters so as to enable it to understand the risks of and form an investment decision with respect to its investment
in the Securities.

 

(e)       Reliance on Exemptions.
The Purchaser understands that the Securities are being offered and sold to it in reliance on specific exemptions from the registration
requirements of the Securities Act and that the Company is relying upon the truth and accuracy of, and the Purchaser’s compliance
with, the representations, warranties, agreements, acknowledgments and understandings of the Purchaser set forth in this Agreement
in order to determine the availability of such exemptions and the eligibility of the Purchaser to acquire the Securities.

 

(f)       No Governmental Review.
The Purchaser understands that no United States federal or state agency or any other government or governmental agency has passed
on or made any recommendation or endorsement of the Securities or the fairness or suitability of the investment in the Securities
nor have such authorities passed upon or endorsed the merits of the offering of the Securities.

 

    	-11-

    	 

    

 

(g)      Authorization; Enforcement;
Validity. The Purchaser is an entity duly organized and validly existing under the laws of the jurisdiction of its organization
with full right, corporate power and authority to enter into and to consummate the transactions contemplated by this Agreement
and otherwise to carry out its obligations hereunder. The execution, delivery and performance by the Purchaser of the transactions
contemplated by this Agreement has been duly authorized by all necessary corporate action on the part of the Purchaser and any
other governmental action with respect to the Purchaser.  This Agreement has been duly executed by the Purchaser, and when
delivered by the Purchaser in accordance with terms hereof, will constitute the valid and legally binding obligation of the Purchaser,
enforceable against it in accordance with its terms, except as such enforceability may be limited by general principles of equity
or applicable bankruptcy, insolvency, reorganization, moratorium, liquidation or similar laws relating to, or affecting generally,
the enforcement of creditors’ rights and remedies.

 

(h)      No Conflicts. The execution,
delivery and performance of this Agreement by the Purchaser and the consummation by the Purchaser of the transactions contemplated
hereby do not and will not (i) result in a violation of the Purchaser’s charter, bylaws, or other similar organizational
documents; (ii) conflict with, or constitute a default (or an event which with notice or lapse of time or both would become a default)
under any agreement, indenture or instrument to which the Purchaser is a party; (iii) result in a violation of any law, rule, regulation,
order, judgment or decree applicable to the Purchaser; or (iv) result in the imposition of a mortgage, pledge, security interest,
encumbrance, charge or other lien on any asset of the Purchaser, except for such conflicts, defaults, terminations, amendments,
accelerations, cancellations, violations and impositions as described in clauses (ii), (iii) or (iv) of this sentence as would
not, individually or in the aggregate, have or result in a material adverse effect on the Purchaser.

 

5.       RESTRICTIONS ON TRANSFER; OWNERSHIP
OF SHARES

 

(a)      Resales. The Purchaser
agrees that the Securities may only be sold or transferred (i) pursuant to an effective registration statement under the Securities
Act, or (ii) pursuant to an exemption from registration under the Securities Act.

 

(b)      Rule 144. The Purchaser
is aware of Rule 144 under the Securities Act and the restrictions imposed thereby and further understands and agrees that so long
as the Purchaser beneficially owns 10% or more of the Company’s then outstanding securities or has a designee selected by
the Purchaser serving on the Board, the Company will deem the Purchaser to be an “affiliate” as defined in Rule 144(a)(1)
and any transfers of the Securities by the Purchaser shall be subject to the limitations applicable to affiliates set forth in
the Securities Act and the rules promulgated thereunder, including without limitation Rule 144.

 

(c)      Legends. The certificate(s)
evidencing the Securities shall bear legends in substantially the following form:

 

    	-12-

    	 

    

 

“THE SECURITIES REPRESENTED
BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE
IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”),
AND, ACCORDINGLY, MAY NOT BE OFFERED, SOLD OR OTHERWISE TRANSFERRED EXCEPT (A) IN AN OFFSHORE TRANSACTION IN ACCORDANCE WITH REGULATION
S OF THE SECURITIES ACT, (B) PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES ACT OR (C) PURSUANT TO AN AVAILABLE
EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT AND IN ACCORDANCE WITH
APPLICABLE STATE SECURITIES LAWS AS EVIDENCED BY A LEGAL OPINION OF COUNSEL TO THE TRANSFEROR TO SUCH EFFECT, THE SUBSTANCE OF
WHICH SHALL BE REASONABLY ACCEPTABLE TO THE COMPANY.”

 

(d)      Agreement to be Bound.
Subject to the other restrictions on transfer set forth or referenced in this Agreement, the Purchaser may assign all of its rights
and obligations hereunder with respect to some or all of the Securities, provided that the transferee has agreed in writing to
be bound by the applicable provisions of this Agreement.

 

6.        BOARD REPRESENTATIVE

 

(a)      Series B Director.
Effective as of the Closing Date, the Company shall take all actions necessary to cause the appointment of the Series B Designee
as a director of the Company (such individual, and all future Series B Designees nominated and elected by Purchaser as a director
of the Company, referred to herein as a “Series B Director”) until a successor is duly elected and qualified.
The Purchaser, as sole holder of the Preferred Stock, shall have the right to nominate and elect the initial Series B Designee
as the Series B Director of the Company. If the Series B Director shall cease to serve as a director for any reason,
the Series B stockholders, voting separately as a series, shall have the right to nominate and elect a replacement director to
serve out the remaining term of the existing Series B Director upon written notice to the Company. The Series B Director shall
be entitled to receive reimbursement of reasonable expenses incurred in connection with attending Board and committee meetings,
but shall not be considered a non-employee director for purposes of receiving any other compensation as a director or a member
of any committee of the Board. In accordance with the provisions of the Certificate of Designation, at such time as less than 40%
of the Shares issued to the Purchaser under this Agreement remain outstanding, the right of the Series B stockholders to elect
the Series B Designee shall automatically terminate, and the Series B Director shall resign from the Board and any committees thereof
on which the Series B Director may serve.

 

(b)      Restrictions on Series
B Designee. The Series B Director (i) shall be bound by confidentiality obligations with respect to the Company and its business
to the same extent as are other directors of the Company and as is the Purchaser pursuant to this Agreement; and (ii) if deemed
necessary by a vote of the majority of the members of the Board (excluding the Series B Director), shall not participate in any
Board deliberations or action (including, but not limited to, Board presentations or discussions), or receive Board information,
relating to any matter to which the Purchaser has any interest that is competing or inconsistent with the interests of the Company.
The Purchaser agrees to cause the Series B Director (and each successor) to comply with the obligations in clause (i) of the preceding
sentence.

 

    	-13-

    	 

    

 

(c)      Board of Directors.
Without the written consent of the holders of a majority of the outstanding Preferred Stock, during any period in which the holders
of the Preferred Stock have the right to elect the Series B Director, the Board shall consist of no more than seven (7) members.

 

7.        CORPORATE OPPORTUNITY POLICY

 

(a)      Section 6.8 of Pyxis SPA.
During any period in which Purchaser has the right to elect the Series B Director the Company shall not, without the consent
of Purchaser, amend Section 6.8 of that certain Stock Purchase Agreement dated March 5, 2003, as amended on May 30,
2003 and February 28, 2005, and as amended as of the date hereof, by and among the Company and Pyxis Innovations Inc. (the
“Pyxis SPA”), a copy of which is attached as Exhibit C.

 

(b)      Series B Director.
In addition to the provisions of Section 6.8 of the Pyxis SPA, the Board of Directors of the Company has adopted this Section 7(b)
in accordance with Section 122(17) of the Delaware General Corporate Law in order to regulate and define the conduct of certain
affairs of the Company as they may involve the Series B Director and Affiliates (as defined below), and the powers, rights,
duties and liabilities of the Company and its officers, directors and stockholders in connection therewith. Nothing in this Section
will regulate or define the conduct of the Series B Director or an Affiliate with respect to affairs not involving a corporate
opportunity (as defined below). Moreover, nothing in this Section will prohibit the Company from entering into contractual arrangements
with the Series B Director or an Affiliate that restrict the Series B Director or an Affiliate from engaging in activities
otherwise allowed by this Section, and the following provisions shall be subject to any such contractual obligation of the Company.

 

(i)         For purposes of this Section 7(b)
only:

 

(A)      A director of the Company
who is Chairman or Vice Chairman of the Board of Directors of the Company or of a committee thereof shall not be deemed to be an
officer of the Company by reason of holding such position (without regard to whether such position is deemed an officer of the
Company under the bylaws of the Company), unless such person is a full-time employee of the Company.

 

(B)      The term “STOCKHOLDER”
shall mean (i) the Purchaser; (ii) any subsidiary or wholly-controlled nonprofit corporation of Purchaser; (iii) any
person or entity directly or indirectly holding the power (under applicable law, contract, or otherwise) to designate fifty percent
(50%) or more of Purchaser’s board of directors; (iv) any successors, by way of merger, consolidation or sale of all
or substantially all of the assets of Purchaser; and (v) any assignees or other transferee of substantially all of the assets
of Purchaser.

 

(C)      The term “AFFILIATE”
shall mean a director, officer, or employee of the Stockholder. No person shall be deemed to be an Affiliate solely by reason of
his or her employment by or affiliation or relationship with the Company.

 

    	-14-

    	 

    

 

(D)      The term “CORPORATE
OPPORTUNITY” shall consist of a business opportunity that (i) an entity is financially able (including, for example,
the ability of the entity to obtain financing or raise capital in respect of such opportunity within a reasonable amount of time)
to undertake at the moment that the opportunity becomes known, (ii) is, from its nature, in the line or lines of the Company’s
existing genetic testing business and is of practical advantage to it, and (iii) is one in which the entity could, but for
the provisions of this Section 7(b), have an interest or reasonable expectancy.

 

(ii)        If the Series B Director
who is also an Affiliate acquires knowledge of a potential transaction or matter that may be a corporate opportunity for both the
Company and the Stockholder then, to the fullest extent permitted by law, such Series B Director: (a) shall be deemed
to have fully satisfied and fulfilled the fiduciary duty of such director to the Company and its stockholders with respect to such
corporate opportunity, (b) shall not be liable to the Company or its other stockholders for breach of any fiduciary duty by
reason of the fact that the Stockholder or any Affiliate pursues or acquires such corporate opportunity for itself, himself, or
herself, or directs such corporate opportunity to the Stockholder or any Affiliate or does not communicate information regarding
such corporate opportunity to the Company, and (c) shall be deemed not to have breached his or her duty of loyalty to the Company
or its stockholders and not to have derived an improper personal benefit therefrom; provided that such director acts in a manner
consistent with the following:

 

(A)      A corporate opportunity offered
to the Series B Director who is an officer of the Company, and who is also a director but not an officer or employee of the
Stockholder, shall belong to the Company, unless such corporate opportunity is, in the first instance, expressly offered to such
person in writing solely in his or her capacity as a director of the Stockholder, in which case such corporate opportunity shall
belong to the Stockholder.

 

(B)      A corporate opportunity offered
to the Series B Director who is not an officer of the Company, and who is also an officer (whether or not a director) or employee
of the Stockholder, shall belong to the Company only if such corporate opportunity is expressly offered to such person (i) during
or in connection with any meeting of the Company's Board of Directors, or any committee thereof, or (ii) in writing solely
in his or her capacity as a director of the Company (and in such case, Stockholder shall use reasonable efforts to cause such person
to provide at least fifteen (15) days notice of such corporate opportunity to the Company); otherwise such corporate opportunity
shall belong to the Stockholder.

 

(C)      Except as otherwise provided
in subparagraphs (A) and (B) above, a corporate opportunity offered to any person who is (i) a director of both the Company
and the Stockholder but not an officer of the Stockholder, (ii) a director of both the Company and the Stockholder but not an officer
of either, or (iii) a director and an officer of both the Company and the Stockholder, shall belong to (x) the Company if
such corporate opportunity is expressly offered to such person solely in his or her capacity as an officer or director of the Company,
and (y) the Stockholder if such corporate opportunity is expressly offered to such person in his or her capacity as an officer
or director of the Stockholder.

 

    	-15-

    	 

    

 

(iii)         Any corporate opportunity
that belongs to the Stockholder or an Affiliate, on the one hand, or to the Company, on the other hand, pursuant to the foregoing
provisions of this Section 7(b) shall not be pursued by the other, unless and until the party to whom the corporate opportunity
belongs determines not to pursue the corporate opportunity and so informs the other party in writing. Notwithstanding the preceding
sentence or any other provision of this Section 7(b), if the party to whom the corporate opportunity belongs does not, within
one year of receipt of notice of the corporate opportunity, begin to pursue, or thereafter continue to pursue, such corporate opportunity
diligently and in good faith, the other party may then pursue such corporate opportunity or direct it to another person.

 

For the avoidance of doubt, nothing
herein is to be construed to expand any powers, rights, duties, or liabilities of the Stockholder or any Affiliate, or to create
any powers, rights, duties, or liabilities of the Stockholder or any Affiliate where they would otherwise not exist, in either
case in respect of or relating to the corporate opportunity doctrine under the Delaware General Corporate Law or other applicable
law.

 

Any person or entity purchasing or
otherwise acquiring any interest in equity securities of the Company shall be deemed to have notice of and to have consented to
the provisions of this Section 7(b). Neither the alteration, amendment or repeal of this Section 7(b) nor the adoption
of any provision of the Company's Bylaws or Certificate of Incorporation inconsistent with this Section shall eliminate or reduce
the effect of this Section 7(b) in respect of any matter occurring, or any cause of action, suit or claim that, but for this
Section 7(b), would accrue or arise, prior to such alteration, amendment, repeal or adoption.

 

Anything in this Section 7(b)
to the contrary notwithstanding, the foregoing provisions of this Section 7(b) shall terminate, expire and have no further
force and effect on the date that no person who is a director, officer or employee of the Company is also a director, officer,
or employee of the Stockholder.

 

8.         PUBLIC STATEMENTS

 

The Company agrees to disclose on a Current
Report on Form 8-K the existence of this Agreement and the transactions contemplated by this Agreement and the material terms,
thereof, including pricing, within the time frame required under Form 8-K. The Purchaser shall not issue any press release, or
otherwise make any such public statement regarding this Agreement or the transactions contemplated by this Agreement (except for
required SEC filings) without the prior written consent of the Company.

 

9.          MISCELLANEOUS

 

(a)       Governing Law. All
questions concerning the construction, validity, enforcement and interpretation of this Agreement shall be governed by the internal
laws of the State of Delaware, United States of America, without giving effect to any choice of law or conflict of law provision
or rule (whether of the State of Delaware or any other jurisdictions) that would cause the application of the laws of any jurisdictions
other than the State of Delaware. If any provision of this Agreement shall be invalid or unenforceable in any jurisdiction, such
invalidity or unenforceability shall not affect the validity or enforceability of the remainder of this Agreement in that jurisdiction
or the validity or enforceability of any provision of this Agreement in any other jurisdiction.

 

    	-16-

    	 

    

 

(b)      Entire Agreement. This
Agreement and the documents referenced herein and therein constitute the entire agreement among the parties hereto with respect
to the subject matter hereof and thereof. There are no restrictions, promises, warranties or undertakings, other than those set
forth or referred to herein and therein. This Agreement and the documents referenced herein and therein supersede all prior agreements
and understandings among the parties hereto with respect to the subject matter hereof and thereof.

 

(c)      Amendments and Waivers.
No provision of this Agreement may be amended or waived other than by an instrument in writing identified as such an amendment
or waiver and signed by the Company and by the Purchaser.

 

(d)      Notices. Any notices,
consents, waivers or other communications required or permitted to be given under the terms of this Agreement must be in writing
and will be deemed to have been delivered: (i) upon receipt, when delivered personally; (ii) upon receipt, when sent by facsimile
(provided confirmation of transmission is mechanically or electronically generated and kept on file by the sending party); or (iii)
upon receipt, when sent via a nationally recognized overnight delivery service, in each case properly addressed to the party to
receive the same. The addresses and facsimile numbers for such communications shall be:

 

If to the Company:

 

Interleukin Genetics, Inc.

135 Beaver Street

Waltham, MA 02452

Telephone:    (781) 398-0700

Facsimile:     (781) 398-0720

Attention:      Lewis H. Bender

                       Chief
Executive Officer

 

with a copy to:

 

Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.

One Financial Center

Boston, MA 02111

Tel:    (617) 542-6000

Fax:   (617) 542-2241

Attn: Brian P. Keane, Esq.

 

If to the Purchaser:

 

Delta Dental Plan of Michigan,
Inc.

4100 Okemos Road

Okemos, MI 48864

Tel:   (517) 347-5451

Fax:  (517) 347-5433

Attn:  Jonathan S. Groat

           Vice
President and General Counsel

 

    	-17-

    	 

    

 

with a copy to:

 

Faegre Baker Daniels LLP

300 North Meridian Street

Suite 2700

Indianapolis, IN 46204

Tel:     (317) 237-1172

Fax:     (317) 237-1000

Attn:   Jason D. Kimpel, Esq.

 

(e)      No Strict Construction.
The language used in this Agreement will be deemed to be the language chosen by the parties to express their mutual intent, and
no rules of strict construction will be applied against any party.

 

(f)      Further Assurances.
Each party shall do and perform, or cause to be done and performed, all such further acts and things, and shall execute and deliver
all such other agreements, certificates, instruments and documents, as the other party may reasonably request in order to carry
out the intent and accomplish the purposes of this Agreement and the consummation of the transactions contemplated hereby.

 

(g)     Severability. If any
provision of this Agreement shall be invalid or unenforceable in any jurisdiction, such invalidity or unenforceability shall not
affect the validity or enforceability of the remainder of this Agreement in that jurisdiction or the validity or enforceability
of any provision of this Agreement in any other jurisdiction.

 

(h)     Successors and Assigns.
This Agreement shall be binding upon and inure to the benefit of the parties and their respective successors and assigns, including
any purchasers of the Shares.

 

(i)       Survival. The representations
and warranties of the Company and the Purchaser contained in Sections 3 and 4, respectively, shall be deemed to be representations
and warranties as of the date hereof and shall survive the Closing and delivery of the Securities, provided that all such representations
and warranties shall terminate three (3) years following the Closing. No investigation by or knowledge of a party or its representatives,
before or after the date of this Agreement, will affect in any manner the representations, warranties, covenants or agreements
of another party set forth in this Agreement (or in any document to be delivered in connection with the consummation of the transactions
contemplated by this Agreement) or the rights to rely thereon, and such representations, warranties, covenants and agreements will
survive any such investigation.

 

(j)      Headings. The headings
of this Agreement are for convenience of reference only and shall not limit or otherwise affect the meaning hereof.

 

(k)      Counterparts. This
Agreement may be executed in identical counterparts, each of which shall be deemed an original but all of which shall constitute
one and the same agreement. This Agreement, once executed by a party, may be delivered to the other party hereto by facsimile transmission
of a copy of this Agreement bearing the signature of the party so delivering this Agreement.

 

[Remainder of page intentionally left blank.

Signature page to follow.]

 

    	-18-

    	 

    

 

IN WITNESS WHEREOF, the parties have caused
this Stock Purchase Agreement to be duly executed as of the date first written above.

 

	 	COMPANY:
	 	 
	 	INTERLEUKIN GENETICS, INC.
	 	 
	 	By:	/s/ Lewis H. Bender
	 	 	Name:  Lewis H. Bender
	 	 	Title: Chief Executive Officer
	 	 
	 	PURCHASER:
	 	 
	 	DELTA DENTAL PLAN OF MICHIGAN, INC.
	 	 
	 	By:	/s/ Laura L. Czelada
	 	 	Name:  Laura L. Czelada
	 	 	Title: President & CEOExecution

 

REGISTRATION RIGHTS AGREEMENT

 

This REGISTRATION RIGHTS AGREEMENT (this
“Agreement”), dated as of June 29, 2012, is by and between INTERLEUKIN GENETICS, INC., a Delaware corporation
(the “Company”), and DELTA DENTAL PLAN OF MICHIGAN, INC., a Michigan nonprofit corporation (the “Shareholder”).
Unless otherwise defined herein, all capitalized terms used herein shall have the meanings ascribed to them in that certain Stock
Purchase Agreement, dated as of even date herewith, by and among the Company and the Shareholder (the “Purchase Agreement”).

 

This Agreement is made pursuant to the
Purchase Agreement. In order to induce the Shareholder to enter into the Purchase Agreement, the Company has agreed to provide
the registration rights provided for in this Agreement to the Shareholder and their respective direct and indirect transferees.
The execution of this Agreement is a condition to the closing of the transactions contemplated by the Purchase Agreement.

 

The parties hereby agree as follows:

 

Section 1. Piggyback Registration
Rights. If the Company at any time and from time to time proposes to register any of its securities under the Securities
Act, for sale to the public, whether for its own account or for the account of other security holders, or both (except with respect
to Special Registration Statements), it will provide written notice to all Holders of its intention to do so. Upon the written
request of a Holder, provided within twenty (20) business days after receipt of any such notice, to register any of the Covered
Shares held by such Holder, the Company will, subject to the limitations and conditions contained herein, use its commercially
reasonable efforts to cause the Covered Shares as to which registration shall have been so requested to be included for registration
in the registration statement proposed to be filed by the Company, all to the extent required to permit the sale or other disposition
of the Covered Shares by such Holder; provided, however, that

 

(a)    If, at any time after giving such
written notice of its intention to register any securities and prior to the effective date of the registration statement filed
in connection with such registration, the Company shall determine for any reason not to register such securities, the Company may,
at its election, give written notice of such determination to all Holders, and thereupon the Company shall be relieved of its obligation
to register any Covered Shares of any Holder in connection with such registration (but not from its obligation to pay, in accordance
with Section 1(d) below, all Registration Expenses incurred by any Holder prior to its receipt of such notice);

 

(b)    If such registration involves an
underwritten offering, and a Holder requests to be included in the Company’s registration, then such Holder must sell its
Covered Shares to the underwriters selected by the Company on the same terms and conditions as apply to the Company or the other
selling shareholders, as applicable (except as otherwise set forth herein);

 

    	 

    	 

    

 

(c)    The number of Registrable Securities
to be included in such an underwritten offering may be reduced if, and to the extent that, the managing underwriter, if any, shall
be of the reasonable opinion that such inclusion would adversely affect the marketing of the securities to be sold by the Company
therein. In the event that the managing underwriter determines that less than all of the Registrable
Securities requested to be registered can be included in such offering, then the Registrable Securities that are included in such
offering shall be apportioned pro rata among the holders of Registrable Securities based on the number of Registrable Securities
held by such holders.  If the number of Registrable Securities requested to be included in an underwritten offering is reduced
pursuant to this Section 1(c), no other stockholder’s securities that are not
Registrable Securities shall be included in such offering.

 

(d)    Notwithstanding anything to the
contrary contained in this Section 1, in the event that there is an underwritten public offering of securities of the
Company pursuant to a registration covering Company securities and a Holder does not elect to sell its Covered Shares to the underwriters
of the Company’s securities in connection with such offering, such Holder shall refrain from selling such Covered Shares
during the period of distribution of the Company’s securities by such underwriters, the period in which the underwriting
syndicate participates in the after market and during any lock-up period requested by such underwriters pursuant to a market standstill
agreement; provided, however, that such Holder shall, in any event, be entitled to sell its Covered Shares commencing
on the 90th day after the effective date of such registration statement; and

 

(e)    All Registration Expenses incurred
by the Company in complying with a registration covering Covered Shares, but excluding any Selling Expenses, shall be borne by
the Company. All Selling Expenses in connection with any registration statement filed pursuant to this Agreement shall be borne
by the Holders on a pro rata basis based on the number of Covered Shares held by such Holders, or by such persons other than the
Company (except to the extent the Company shall be a seller), as they may agree.

 

Section 2. Indemnification.
In the event any Covered Shares are included in a registration statement under Section 1:

 

(a)    To the extent permitted by law,
the Company will indemnify and hold harmless the Holders, the officers and directors of the Holders and each such person or entity,
if any, who controls such Holders within the meaning of the Securities Act or the 1934 Act against any losses, claims, damages,
or liabilities (joint or several) to which they may become subject under the Securities Act, the 1934 Act or other federal or state
law, insofar as such losses, claims, damages, or liabilities (or actions in respect thereof) arise out of or are based upon any
of the following statements, omissions or violations (collectively a “Violation”): (i) any untrue statement
or alleged untrue statement of a material fact contained in such registration statement, including any preliminary prospectus or
final prospectus contained therein or any amendments or supplements thereto, (ii) the omission or alleged omission to state
therein a material fact required to be stated therein, or necessary to make the statements therein not misleading, or (iii) any
violation or alleged violation by the Company of the Securities Act, the 1934 Act, any state securities law or any rule or regulation
promulgated under the Securities Act, the 1934 Act or any state securities law; and the Company will pay to the Holders, officers,
directors or controlling persons or entities, as incurred, any legal or other expenses reasonably incurred by them in connection
with investigating or defending any such loss, claim, damage, liability, or action; provided, however, that the indemnity agreement
contained in this Section 2(a) shall not apply to amounts paid in settlement of any such loss, claim, damage, liability,
or action if such settlement is effected without the consent of the Company (which consent shall not be unreasonably withheld),
nor shall the Company be liable in any such case for any such loss, claim, damage, liability, or action to the extent that it arises
out of or is based upon a Violation which occurs in reliance upon and in conformity with written information furnished expressly
for use in connection with such registration by any Holder.

 

    	2

    	 

    

 

(b)    To the extent permitted by law,
each selling Holder will indemnify and hold harmless the Company, each of its directors, each of its officers who has signed the
registration statement, each person, if any, who controls the Company within the meaning of the Securities Act, any underwriter,
any other shareholder selling securities in such registration statement and any controlling person of any such underwriter or other
shareholder, against any losses, claims, damages, or liabilities (joint or several) to which any of the foregoing persons may become
subject, under the Securities Act, the 1934 Act or other federal or state law, insofar as such losses, claims, damages, or liabilities
(or actions in respect thereto) arise out of or are based upon any Violation, in each case to the extent (and only to the extent)
that such Violation occurs in reliance upon and in conformity with written information furnished by such Holder expressly for use
in connection with such registration; and such Holder will pay, as incurred, any legal or other expenses reasonably incurred by
any person intended to be indemnified pursuant to this Section 2(b), in connection with investigating or defending
any such loss, claim, damage, liability, or action; provided, however, that the indemnity agreement contained in this Section 2(b)
shall not apply to amounts paid in settlement of any such loss, claim, damage, liability or action if such settlement is effected
without the consent of such Holder, which consent shall not be unreasonably withheld; provided, that, in no event shall any indemnity
under this Section 2(b) exceed the net proceeds from the offering received by such Holder, except in the case of fraud
or willful misconduct by such Holder.

 

(c)    Promptly after receipt by an indemnified
party under this Section 2 of notice of the commencement of any action (including any governmental action), such indemnified
party will, if a claim in respect thereof is to be made against any indemnifying party under this Section 2, deliver
to the indemnifying party a written notice of the commencement thereof and the indemnifying party shall have the right to participate
in, and, to the extent the indemnifying party so desires, jointly with any other indemnifying party similarly noticed, to assume
the defense thereof with counsel mutually satisfactory to the parties; provided, however, that an indemnified party shall have
the right to retain its own counsel, with the fees and expenses to be paid by the indemnifying party, if representation of such
indemnified party by the counsel retained by the indemnifying party would be inappropriate due to actual or potential differing
interests between such indemnified party and any other party represented by such counsel in such proceeding, provided, however,
that an indemnifying party shall only be required to pay the fees and expenses of one counsel for all indemnified parties in any
such proceeding.

 

(d)    If the indemnification provided
for in this Section 2 is held by a court of competent jurisdiction to be unavailable to an indemnified party with respect
to any loss, liability, claim, damage or expense referred to therein, then the indemnifying party, in lieu of indemnifying such
indemnified party hereunder, shall contribute to the amount paid or payable by such indemnified party as a result of such loss,
liability, claim, damage or expense in such proportion as is appropriate to reflect the relative fault of the indemnifying party
on the one hand and of the indemnified party on the other in connection with the statements or omissions that resulted in such
loss, liability, claim, damage or expense as well as any other relevant equitable considerations; provided, that, in no event shall
any contribution by a Holder under this Section 2(d) exceed the gross proceeds from the offering received by such Holder.
The relative fault of the indemnifying party and of the indemnified party shall be determined by reference to, among other things,
whether the untrue or alleged untrue statement of a material fact or the omission to state a material fact relates to information
supplied by the indemnifying party or by the indemnified party and the parties’ relative intent, knowledge, access to information
and opportunity to correct or prevent such statement or omission.

 

    	3

    	 

    

 

(e)    The obligations of the Company
and the Holders under this Section 2 shall survive the completion of any offering of Covered Shares in a registration
statement under Section 1, and otherwise.

 

Section 3. Duration of Agreement.
The Company shall have no obligation pursuant to this Agreement with respect to any Covered Shares proposed to be sold by a Holder
in a registration pursuant to this Agreement if, in the written opinion of outside counsel to the Company (which counsel must be
acceptable to the Holders in the exercise of its or their reasonable discretion) delivered to the Holders, (i) all such Covered
Shares proposed to be sold by a Holder may be sold in a single transaction without registration under the Securities Act pursuant
to Rule 144, and (ii) the Company has been subject to the reporting requirements of Section 13 or 15(d) of the Exchange
Act for a period of at least ninety (90) days and is current in the filing of all such required reports.

 

Section 4. Rule 144. The
Company shall use commercially reasonable efforts to timely file the reports required to be filed by it under the 1934 Act or the
Securities Act (including the reports under Section 13 and 15(d) of the 1934 Act referred to in subparagraph (c)(1) of
Rule 144) and the rules and regulations adopted by the Commission thereunder to enable such Holders to sell Covered Shares without
registration under the Securities Act within the limitations of the exemption provided by Rule 144 and or any similar or successor
rule or regulation hereafter adopted by the Commission.

 

Section 5. Headings. Headings
of articles, sections and paragraphs of this Agreement are inserted for convenience of reference only and shall not affect the
interpretation or be deemed to constitute a part hereof.

 

Section 6. Severability.
In the event that any one or more of the provisions contained in this Agreement or in any other instrument referred to herein shall,
for any reason, be held to be invalid, illegal or unenforceable, such illegality, invalidity or unenforceability shall not affect
any other provisions of this Agreement.

 

Section 7. Benefits of Agreement.
Nothing expressed by or mentioned in this Agreement is intended or shall be construed to give any person other than the parties
hereto and their respective successors and permitted assigns and transferees any legal or equitable right, remedy or claim under
or in respect of this Agreement or any provision herein contained, this Agreement and all conditions and provisions hereof being
intended to be and being for the sole and exclusive benefit of the parties hereto and their respective successors and permitted
assigns and transferees. Anything herein to the contrary notwithstanding, each Holder shall have the right to assign its rights
hereunder to any Person that is a transferee or assignee of Covered Shares, provided that such Person shall agree in writing to
be irrevocably bound by, and to comply with, all applicable provisions of this Agreement as a “Holder”.

 

    	4

    	 

    

 

Section 8. Notices. Any notice
or other communications required or permitted hereunder shall be deemed to be sufficient and received if contained in a written
instrument delivered in person or by courier or duly sent by first class certified mail, postage prepaid, or by facsimile or email
addressed to such party at the address, email address or facsimile number set forth below:

 

if to the Company:

Interleukin Genetics, Inc.

135 Beaver Street

Waltham, MA 02452

Telephone:   (781) 398-0700

Facsimile:    (781) 398-0720

Attn:    Lewis H. Bender

Chief Executive Officer

 

with a copy to:

Mintz, Levin, Cohn, Ferris, Glovsky
and Popeo, P.C.

One Financial Center

Boston, MA 02111

Tel:    (617) 542-6000

Fax:    (617) 542-2241

Attn:    Brian P. Keane, Esq.

 

if to the Shareholder:

Delta Dental Plan of Michigan,
Inc.

4100 Okemos Road

Okemos, MI 48864

Tel:    (517) 347-5451

Fax:    (517) 347-5433

Attn:   Jonathan S. Groat

Vice President and General
Counsel

with a copy to:

Faegre Baker Daniels LLP

300 North Meridian Street

Suite 2700

Indianapolis, IN 46204

Tel:    (317) 237-1172

Fax:    (317) 237-1000

Attn:    Jason D. Kimpel, Esq.

 

or, in any case, at such other address, email address or facsimile
number as shall have been furnished in writing by such party to the other parties hereto. All such notices, requests, consents
and other communications shall be deemed to have been received (a) in the case of personal or courier delivery, on the date
of such delivery, (b) in the case of mailing, on the fifth business day following the date of such mailing and (c) in
the case of facsimile or email transmission, when received (provided confirmation of transmission is mechanically or electronically
generated and kept in a file by sending party).

 

    	5

    	 

    

 

Section 9. Modification.
Except as otherwise provided herein, neither this Agreement nor any provision hereof may be modified, changed, discharged or terminated
except by an instrument in writing signed by the party against whom the enforcement of any modification, change, discharge or termination
is sought or by the agreement of the Company and the Shareholder.

 

Section 10. Counterparts; Execution.
This Agreement and any amendments hereto may be executed and delivered in one or more counterparts, and by the different parties
hereto in separate counterparts, each of which when executed shall be deemed to be an original, but all of which taken together
shall constitute one and the same agreement, and shall become effective when counterparts have been signed by each party hereto
and delivered to the other parties hereto. In the event that any signature to this Agreement or any amendment hereto is delivered
by facsimile transmission or by e-mail delivery of a portable document format data file, such signature shall create a valid and
binding obligation of the party executing (or on whose behalf such signature is executed) with the same force and effect as if
such facsimile or “.pdf” signature page were an original thereof.

 

Section 11. Governing Law.
THIS AGREEMENT AND THE OTHER TRANSACTION DOCUMENTS SHALL BE GOVERNED BY, AND CONSTRUED ACCORDING TO THE LAWS OF THE STATE OF
DELAWARE, WITHOUT GIVING EFFECT TO PRINCIPLES OF CONFLICTS OF LAW THEREOF.

 

Section 12. Waiver of Jury Trial.
THE PARTIES HERETO HEREBY IRREVOCABLY WAIVE ANY RIGHT TO TRIAL BY JURY IN ANY PROCEEDING ARISING OUT OF OR RELATING TO THIS AGREEMENT,
OR ANY OF THE TRANSACTIONS CONTEMPLATED HEREBY, WHETHER NOW EXISTING OR HEREAFTER ARISING, AND WHETHER SOUNDING IN CONTRACT, TORT
OR OTHERWISE. EACH PARTY AGREES THAT ANY OTHER PARTY HERETO MAY FILE A COPY OF THIS SECTION WITH ANY COURT AS WRITTEN EVIDENCE
OF THE KNOWING, VOLUNTARY AND BARGAINED-FOR AGREEMENT AMONG THE PARTIES IRREVOCABLY TO WAIVE TRIAL BY JURY AND THAT ANY PROCEEDING
WHATSOEVER BETWEEN THEM RELATING TO THIS AGREEMENT OR ANY OF THE CONTEMPLATED TRANSACTIONS SHALL INSTEAD BE TRIED IN A COURT OF
COMPETENT JURISDICTION BY A JUDGE SITTING WITHOUT A JURY.

 

Section 13. Definitions.
The below terms have the stated definitions:

 

(a)    “1934 Act”
means the Securities Exchange Act of 1934, as amended.

 

(b)    “Covered Shares”
shall mean all shares of Common Stock of the Company issued to the Shareholder, or any successor to or assignee of the rights of
the Shareholder, (i) pursuant to the terms of the Purchase Agreement, (ii) pursuant to any conversion of the Preferred
Stock, or (iii) pursuant to any stock dividend or other stock right arising out of the ownership of Preferred Stock or Common
Stock issued upon conversion of the Preferred Stock of the Company. Covered Shares shall also include any shares issued to the
Shareholder or any successor to or assignee of the rights of the Shareholder in consideration of Preferred Stock or Common Stock
issued upon conversion of the Preferred Stock as a result of any reorganization, merger or other restructure of the Company.

 

    	6

    	 

    

 

(c)    “Holder”
means any person holding Covered Shares or shares of Preferred Stock, including, without limitation, the Shareholder, its successors
and permitted assigns.

 

(d)    “Register,”
“registered,” and “registration” refer to a registration effected by preparing and filing
a registration statement in compliance with the Securities Act, and the declaration or ordering of effectiveness of such registration
statement or document.

 

(e)    “Registrable
Securities” means the Covered Shares and any other securities of the Company that are subject to registration rights
agreements, including (i) that certain Registration Rights Agreement dated August 9, 2002, (ii) that certain Registration
Rights Agreement between the Company and Pyxis Innovations Inc. dated March 5, 2003.

 

(f)    “Registration
Expenses” shall mean all reasonable expenses incurred by the Company in complying with Section 1 hereof,
including, without limitation, all registration and filing fees, printing expenses, fees and disbursements of counsel for the Company,
fees and disbursements of one counsel for the Holders selected by holders of at least a majority of the Covered Shares included
in the applicable registration, not to exceed $50,000, blue sky fees and expenses and the expense of any special audits incident
to or required by any such registration (but excluding the compensation of regular employees of the Company which shall be paid
in any event by the Company).

 

(g)    “SEC”
or “Commission” means the United States Securities and Exchange Commission.

 

(h)    “Securities
Act” shall mean the Securities Act of 1933, as amended.

 

(i)    “Selling
Expenses” shall mean all underwriting discounts, brokerage fees, and selling commissions incurred in connection with
registrations, filings, or qualifications of Covered Shares pursuant to Section 1 hereof.

 

(j)    “Special
Registration Statement” shall mean (i) a registration statement relating to any employee benefit plan (ii) a
registration statement with respect to any corporate reorganization or transaction under Rule 145 of the Securities Act, including
any registration statements related to the issuance or resale of securities issued in such a transaction, or (iii) a registration
statement related to securities issued upon conversion of debt securities.

 

[REMAINDER OF PAGE INTENTIONALLY LEFT BLANK;
SIGNATURE PAGE TO FOLLOW]

 

    	7

    	 

    

 

IN WITNESS WHEREOF, each of the parties hereto has executed
this Registration Rights Agreement as of the day and year first above written.

 

	 	COMPANY:
	 	 
	 	INTERLEUKIN GENETICS, INC.
	 	a Delaware corporation
	 	 
	 	By:	/s/ Lewis H. Bender
	 	 	 
	 	Name:	Lewis H. Bender
	 	 	 
	 	Title:	Chief Executive Officer
	 	 
	 	SHAREHOLDER:
	 	 
	 	DELTA DENTAL PLAN OF 
 MICHIGAN, INC.
	 	a Michigan nonprofit corporation
	 	 
	 	By:	/s/ Laura L. Czelada
	 	 	 
	 	Name:	Laura L. Czelada
	 	 	 
	 	Title:	President & CEO

 

    	8

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