Document:

<PAGE>
                                                                   EXHIBIT 10.15
                                                 ****denotes information omitted
                                                       pursuant to a request for
                                           confidential treatment under Rule 406

                           GROUP PURCHASING AGREEMENT

This Agreement entered into by and between INTERNATIONAL PHYSICIAN NETWORKS, LLC
D/B/A/ INTERNATIONAL UROLOGY NETWORK located at World Trade Center, 401 East
Pratt Street, Baltimore, MD, 21202, on behalf of itself and on behalf of its
members (hereinafter referred to as "GPO"), and VALERA PHARMACEUTICALS, INC., a
Delaware corporation with offices at 8 Clarke Drive, Cranbury, NJ 08512
(hereinafter referred to as "Valera").

1.    TYPE OF PROVIDER:  GPO represents and warrants that it is
      established as a group purchasing organization as defined in 42 CFR
      1001.952 (j).

2.    GPO MEMBERS

      A.    GPO will supply Valera with a list of its current members and their
            corresponding addresses, DEA numbers and authorized specialty
            distributors or wholesalers. GPO will also list what type of
            provider each member is (e.g., clinic, physician office, etc. . .
            .). GPO will notify Valera of membership changes on a monthly basis.

      B.    At all times, "Eligible Members" shall mean, collectively, physician
            practices and/or clients who are members of the GPO or the Pharmacy
            Member identified below in Section 2(C) of this Agreement. Only
            Eligible Members shall be entitled to purchase Products hereunder.
            New Eligible Members added by GPO after execution of this Agreement
            will be able to purchase Products under the terms of this Agreement
            thirty- (30) days after GPO notifies Valera of this addition.

      C.    For the purposes of this Agreement, the Pharmacy Member shall be US
            Bioservices Corporation, which at all times throughout the term of
            this Agreement shall be a licensed mail order or specialty pharmacy
            that: (i) in connection with the prescription by a licensed health
            care professional dispenses drugs to physicians and patients; (ii)
            is willing to dispense Products purchased under this Agreement only
            to patients of Eligible Member physicians upon request by a health
            care provider, patients, or the patient's payer, and to the extent
            permissible under such payer coverage policies, is able and willing
            to assume complete financial risk for dispensed Product(s) costs,
            including costs related to its infusion by filing claims with the
            payer(s) and collecting and accepting any such patients' and payers'
            reimbursement as complete payment; and (iii) offers and is able to
            provide drug management and patient care support services.

      D.    Upon execution of this Agreement, GPO shall notify each Eligible
            Member about the terms of this Agreement and it shall also notify
            new Eligible Members after they join GPO. GPO shall ensure that its
            Eligible Members comply with all the terms contained herein.
<PAGE>
3.   PRODUCTS AND PRICES

      A.    Attached hereto, as Exhibit A, is a list of the Valera products
            ("Products") covered by this Agreement and corresponding prices that
            shall be available for all purchases of Eligible Members throughout
            the term of this Agreement, including the related percentage
            reduction provided for hereunder ("Contract Prices"). Eligible
            Members may purchase the Products from GPO's designated wholesale
            distributor, Besse Medical ("Besse"), subject to distribution terms
            agreed upon by and between Besse and Valera, or such other
            authorized distributor approved by Valera, at a price equal to the
            Contract Price, plus any markup, other fee or markdown charged or
            allowed to the Eligible Member by such specialty distributor or
            wholesaler for its services. The amount of any such markup, fee or
            markdown is strictly a matter between the Eligible Member and the
            specialty distributor or wholesaler and is not a part of this
            Agreement.

      B.    GPO will supply Valera with a list of the individual facilities (and
            corresponding addresses and DEA numbers) where each Eligible Member
            will purchase Products.

      C.    Subsequent to the first contract year the Contract Prices will be
            subject to annual price adjustments by Valera; provided, however,
            that any discount provided to the GPO's Eligible Members pursuant to
            Exhibit A of this Agreement, or any other price reductions provided
            to the Eligible Members shall not be modified or otherwise adjusted
            without the mutual agreement of the Parties.

      D.    GPO will receive fees from Valera as set forth on Exhibit B, a copy
            of which is attached hereto and incorporated herein by reference.
            GPO represents and warrants that it has entered into a written
            agreement with its Eligible Members and that such agreement
            describes the fee that GPO will receive hereunder from Valera to the
            extent required under applicable laws and regulations. GPO furthers
            represents and warrants that it will disclose in writing to each of
            its Eligible Members, at least annually, the amount GPO received
            from Valera with respect to purchases made by or on behalf of such
            Eligible Member.

4.   PRODUCT STATUS

      GPO shall inform its members about this arrangement and the Products
      covered by the terms of this Agreement, including providing its members
      the appropriate clinical and scientific information regarding the
      Products. The provision of such clinical and/or scientific information
      shall occur through various venues subject to the limitations set forth on
      Exhibit B, Paragraph B (iv) of this Agreement, including at least the
      programs, meetings, and communications consistent with the obligations set
      forth on Exhibit B of this Agreement. The Parties understand and agree
      that nothing herein shall require any of the GPO's members to purchase any
      of the Products and/or Valera's services, and that

--------------------------------------------------------------------------------
Valera GPO Agreement                Page 2
<PAGE>
      nothing herein is intended to interfere with all Eligible Members'
      utilization of their independent medical judgment in prescribing Products.

5.   CONTRACT PERIOD

      The term of this Agreement will be effective as of December 1, 2004, and
      will expire on November 30, 2005.

 6.   TERMINATION

      A.    Either Party may terminate this Agreement if the other Party
            breaches any of its obligations or provisions of this Agreement;
            provided however, that the defaulting Party will be given not less
            than thirty- (30) days' prior written notice of such default and the
            opportunity to cure the default during such period.

      B.    In addition, Valera may immediately terminate any Eligible Member's
            ability to participate in this Agreement in the event it determines
            that such Eligible Member has violated any material terms and
            condition of such Eligible Members' participation hereunder.

 7.   PRODUCT AVAILABILITY

      This Agreement is subject to Product availability. It is understood that
      in situations of short supply, orders of Eligible Members may have to be
      reduced. Valera will take reasonable steps to provide Products in short
      supply to all of its customers, including Eligible Members, on an
      equitable basis.

 8.   RETURNED GOODS

      Products may be returned under the standard Valera Returned Goods Policy,
      a copy of which will be supplied to GPO upon request.

 9.   CONFIDENTIALITY

      The Parties will keep all the terms, conditions, and prices in this
      Agreement confidential.

 10.  GENERAL TERMS AND CONDITIONS

      A.    GPO and Eligible Members agree to provide complete information
            concerning the discounted prices on the Products available under
            this Agreement, including any rebate which may be applicable, to
            representatives of Medicare, Medicaid, and other Federal health care
            programs (as defined in 42 U.S.C.SectioN 1320a-7b(f)) upon request.
            If GPO or any Eligible Member is a cost reporting entity, it will
            fully and accurately report the amount of the discount, including
            any rebates earned, under

--------------------------------------------------------------------------------
Valera GPO Agreement                Page 3
<PAGE>
            this Agreement as a discount on Medicare, Medicaid and other Federal
            health care program cost reports.

      B.    The obligations of either Party hereunder will be suspended in the
            event that such Party is hindered or prevented from complying
            therewith because of labor disturbances (including strikes and
            lockouts), wars, fires, storms, accidents, or interference or any
            other cause beyond such Party's reasonable control.

      C.    Any failure of either Party to require the other Party to comply
            with any provision of this Agreement will not be deemed a waiver of
            such provision or any other provision of this Agreement.

      D.    Each Party represents that its performance under this Agreement will
            be in full compliance with any and all applicable laws and
            regulations. GPO and Eligible Members shall comply with all
            applicable laws relating to the dispensing of Products purchased
            under this Agreement, including without limitation any state and/or
            local laws and regulations relating to drug product selection and
            consumer protection, and will fully advise consumers, if required,
            of the basis on which any product selection has been made, including
            the existence of this Agreement.

      E.    GPO, Eligible Members, Besse, and any other designated specialty
            distributors/wholesalers will not be deemed agents of Valera.

      F.    The Contract Prices and terms of this Agreement shall apply only to
            those facilities of Eligible Members located in the continental
            U.S., Alaska and Hawaii.

      G.    This Agreement will be construed in accordance with the laws of the
            State of Delaware with the exception of its choice of law
            principles. Any clause, section or paragraph of this Agreement which
            is determined by a court of competent jurisdiction to be illegal,
            invalid or unenforceable will be deemed severed from the remainder
            of the Agreement and will have no effect on the legality, validity,
            or enforceability of the remaining provisions.

      H.    Original copies of all notices hereunder will be hand-delivered,
            sent by first class mail or overnight mail to the addresses
            specified in this Agreement. Notice will be deemed given on the date
            of mailing.

      I.    GPO or Eligible Members may not assign the rights or obligations
            contained in this Agreement except with the prior written consent of
            Valera.

      J.    This Agreement and the Exhibits referenced herein represent the
            entire understanding between the parties with respect to the subject
            matter hereof, and supersedes any previous agreements entered into
            by the parties relating to the subject matter hereof. Any amendment
            or renewal of this Agreement or any Exhibit shall be in writing and
            signed by both parties.

--------------------------------------------------------------------------------
Valera GPO Agreement                Page 4
<PAGE>
      K.    Execution of this Agreement by the Parties indicates acceptance of
            the terms and conditions herein on behalf of itself and on behalf of
            its members.

Each of the signatories represents that he/she is duly authorized to sign this
Agreement, and this Agreement is a binding obligation of the Party on whose
behalf it is signed.

AGREED AND ACCEPTED:

      VALERA PHARMACEUTICALS, INC.

      By:    /s/ David S. Tierney
             -------------------------------

      Title: President and CEO
             ----------------------------

      Date:  3/18/2005
             -----------------------------

      INTERNATIONAL PHYSICIAN NETWORKS, L.L.C.

      By:    /s/ Anthony Corrao
             -------------------------------

      Title: President GM IPN
             ----------------------------

      Date:  3-21-05
             -----------------------------

--------------------------------------------------------------------------------
Valera GPO Agreement                Page 5
<PAGE>
                                    EXHIBIT A

A.    PRODUCTS COVERED BY THIS AGREEMENT AND RELATED CONTRACT PRICE (1)

<TABLE>
<CAPTION>
                                                  Q1/05
                     VANTAS                   CONTRACT PRICE   DISCOUNT OF WAC
                     ------                   --------------   ---------------
<S>                                           <C>              <C>
      IUN Physician Members                        ****                 ****
      US Bioservices                               ****                 ****
</TABLE>

<TABLE>
<CAPTION>
                                                  Q2/05
                     VANTAS                   CONTRACT PRICE   DISCOUNT OF WAC
                     ------                   --------------   ---------------
<S>                                           <C>              <C>
      IUN Physician Members                        ****                 ****
      US Bioservices                               ****                 ****
</TABLE>

--------

(1)  The parties will determine the Contract Price and related discounts for Q3
     and Q4 2005 upon the calculation and configuration of the Products Average
     Sales Price.

--------------------------------------------------------------------------------
Valera GPO Agreement                Page 6
<PAGE>
                                    EXHIBIT B

A.    ADMINISTRATIVE FEES

      GPO shall receive a **** administrative fee on aggregate sales of the
      Products to Eligible Members at the Contract Price.

      The fees provided for above shall be paid by Valera to GPO quarterly,
      within sixty- (60) days after each three- (3) month period during the term
      of this Agreement. Valera agrees to provide GPO with reasonable access to
      all materials and documents that may be necessary to ensure the accuracy
      of any fees paid hereunder.

B.    ADMINISTRATIVE ASSISTANCE

      GPO will provide Valera the following administrative assistance subject to
      the limitations set forth below:

      i.   Provide Eligible Member data at physician level on utilization
           (de-identified as to patient identity as required by law).

      ii.  Inform Eligible Members about the terms of this Agreement, including
           the distribution services available through Besse, and otherwise
           administer the terms of this Agreement on behalf of Valera.

      iii. Allow Valera representatives the opportunity to attend designated
           meetings of the GPO's members during the term of this Agreement.

      iv.  At such time that sales of the Product to Eligible Members exceed
           **** on a quarterly basis, GPO shall provide the following services
           on behalf of Valera, provided, however, that the aggregate costs of
           such services shall not exceed ****):

           -     GPO will conduct regional and local educational meetings of
                 EliGIBle Members to inform them of clinical and/or scientific
                 developments related to the Product;

           -     GPO will conduct regional and local educational meetings
                 relateD To reimbursement of Valera's Products, and such other
                 administrative topics mutually agreed upon by the Parties.

--------------------------------------------------------------------------------
Valera GPO Agreement                Page 7
<PAGE>
                                  ATTACHMENT 1

<TABLE>
<CAPTION>
                                                                              Designated
                                                                               Specialty
    Clinic or Physician                                                     Distributor or
          Office              DEA #           Address           Phone #    Wholesaler/Address
          ------              -----           -------           -------    ------------------
<S>                           <C>             <C>               <C>        <C>

</TABLE>

--------------------------------------------------------------------------------
Valera GPO Agreement                Page 8<PAGE>
                                                                   EXHIBIT 10.16
                                                 ****denotes information omitted
                                                       pursuant to a request for
                                           confidential treatment under Rule 406

                           GROUP PURCHASING AGREEMENT

This Agreement entered into by and between INTERNATIONAL PHYSICIAN NETWORKS, LLC
D/B/A/ INTERNATIONAL UROLOGY NETWORK located at World Trade Center, 401 East
Pratt Street, Baltimore, MD, 21202, on behalf of itself and on behalf of its
members (hereinafter referred to as "GPO"), and VALERA PHARMACEUTICALS, INC., a
Delaware corporation with offices at 8 Clarke Drive, Cranbury, NJ 08512
(hereinafter referred to as "Valera").

1.    TYPE OF PROVIDER:  GPO represents and warrants that it is
      established as a group purchasing organization as defined in 42 CFR
      1001.952 (j), and is authorized to enter into group purchasing
      arrangements collectively on behalf of the physician-practice
      members of U.S. Urology, LLC, a Texas limited liability
      corporation.  Such physician-practices also are members of GPO's
      group purchasing network ("U.S. Urology Practices").

2.    GPO MEMBERS

      A.    GPO will supply Valera with a list of the current U.S. Urology
            Practices and their corresponding addresses, DEA numbers and
            authorized specialty distributors or wholesalers. GPO will also list
            what type of provider each member is (e.g., clinic, physician
            office, etc. . . .). GPO will notify Valera of membership changes on
            a monthly basis.

      B.    At all times, "Eligible Members" shall mean collectively: U.S.
            Urology Practices that are members of the GPO or the Pharmacy Member
            identified below in Section 2(C) of this Agreement. Only Eligible
            Members shall be entitled to purchase Products hereunder. New
            Eligible Members added by GPO after execution of this Agreement will
            be able to purchase Products under the terms of this Agreement
            thirty- (30) days after GPO notifies Valera of this addition.

      C.    For the purposes of this Agreement, the Pharmacy Member shall be US
            Bioservices Corporation, which at all times throughout the term of
            this Agreement shall be a licensed mail order or specialty pharmacy
            that: (i) in connection with the prescription by a licensed health
            care professional dispenses drugs to physicians and patients; (ii)
            is willing to dispense Products purchased under this Agreement only
            to patients of Eligible Member physicians upon request by a health
            care provider, patients, or the patient's payer, and to the extent
            permissible under such payer coverage policies, is able and willing
            to assume complete financial risk for dispensed Product(s) costs,
            including costs related to its infusion by filing claims with the
            payer(s) and collecting and accepting any such patients' and payers'
            reimbursement as complete payment; and (iii) offers and is able to
            provide drug management and patient care support services.

      D.    Upon execution of this Agreement, GPO shall notify each Eligible
            Member about the terms of this Agreement and it shall also notify
            new Eligible Members after they join U.S. Urology, LLC.
<PAGE>
 3.   PRODUCTS AND PRICES

      A.    Attached hereto, as Exhibit A, is a list of the Valera products
            ("Products") covered by this Agreement and corresponding prices that
            shall be available for all purchases of Eligible Members throughout
            the term of this Agreement, including the related percentage
            reduction provided for hereunder ("Contract Prices"). Eligible
            Members may purchase the Products from GPO's designated wholesale
            distributor, Besse Medical ("Besse"), subject to distribution terms
            agreed upon by and between Besse and Valera, or such other
            authorized distributor approved by Valera, at a price equal to the
            Contract Price, plus any markup. other fee or markdown charged or
            allowed to the Eligible Member by such specialty distributor or
            wholesaler for its services. The amount of any such markup, fee or
            markdown is strictly a matter between the Eligible Member and the
            specialty distributor or wholesaler and is not a part of this
            Agreement.

      B.    GPO will supply Valera with a list of the individual facilities (and
            corresponding addresses and DEA numbers) where each Eligible Member
            will purchase Products.

      C.    Subsequent to the first contract year the Contract Prices will be
            subject to annual price adjustments by Valera; provided, however,
            that any discount provided to the Eligible Members pursuant to
            Exhibit A of this Agreement, or any other price reductions provided
            to the Eligible Members shall not be modified or otherwise adjusted
            without the mutual agreement of the parties.

      D.    GPO will receive fees from Valera as set forth on Exhibit B, a copy
            of which is attached hereto and incorporated herein by reference.
            GPO represents and warrants that it has entered into a written
            agreement with its Eligible Members and that such agreement
            describes the fee that GPO will receive hereunder from Valera to the
            extent required under applicable laws and regulations. GPO furthers
            represents and warrants that it will disclose in writing to each of
            its Eligible Members, at least annually, the amount GPO received
            from Valera with respect to purchases made by or on behalf of such
            Eligible Member.

 4.   PRODUCT STATUS

      GPO shall inform the Eligible Members about this arrangement and the
      Products covered by the terms of this Agreement, including providing its
      Eligible Members the appropriate clinical and scientific information
      regarding the Products. The provision of such clinical and/or scientific
      information shall occur through various venues subject to the limitations
      set forth on Exhibit B, Paragraph B (iv) of this Agreement, including at
      least the programs, meetings, and communications consistent with the
      obligations set forth on Exhibit B of this Agreement. The parties
      understand and agree that nothing herein shall require any of the Eligible
      Members to purchase any of the Products and/or Valera's

--------------------------------------------------------------------------------
Valera GPO Agreement for U.S. Urology   Page 2
<PAGE>
      services, and that nothing herein is intended to interfere with all
      Eligible Members' utilization of their independent medical judgment in
      prescribing Products.

 5.   CONTRACT PERIOD

      The term of this Agreement will be effective as of December 1, 2004, and
      will expire on November 30, 2005.

 6.   TERMINATION

      A.    Either Party may terminate this Agreement if the other Party
            breaches any of its obligations or provisions of this Agreement;
            provided however, that the defaulting Party will be given not less
            than thirty- (30) days' prior written notice of such default and the
            opportunity to cure the default during such period.

      B.    In addition, Valera may immediately terminate any Eligible Member's
            ability to participate in this Agreement in the event it determines
            that such Eligible Member has violated any material terms and
            condition of such Eligible Member's participation hereunder.

 7.   PRODUCT AVAILABILITY

      This Agreement is subject to Product availability. It is understood that
      in situations of short supply, orders of Eligible Members may have to be
      reduced. Valera will take reasonable steps to provide Products in short
      supply to all of its customers, including Eligible Members, on an
      equitable basis.

 8.   RETURNED GOODS

      Products may be returned under the standard Valera Returned Goods Policy,
      a copy of which will be supplied to GPO upon request.

 9.   CONFIDENTIALITY

      The parties will keep all the terms, conditions, and prices in this
      Agreement confidential.

 10.  GENERAL TERMS AND CONDITIONS

      A.    GPO and Eligible Members agree to provide complete information
            concerning the discounted prices on the Products available under
            this Agreement, including any rebate which may be applicable, to
            representatives of Medicare, Medicaid, and other Federal health care
            programs (as defined in 42 U.S.C.Section 1320a-7b(f)) upon request.
            If GPO or any Eligible Member is a cost reporting entity, it will
            fully and accurately report the amount of the discount, including
            any rebates earned, under

--------------------------------------------------------------------------------
Valera GPO Agreement for U.S. Urology   Page 3
<PAGE>
            this Agreement as a discount on Medicare, Medicaid and other Federal
            health care program cost reports.

      B.    The obligations of either Party hereunder will be suspended in the
            event that such Party is hindered or prevented from complying
            therewith because of labor disturbances (including strikes and
            lockouts), wars, fires, storms, accidents, or interference or any
            other cause beyond such Party's reasonable control.

      C.    Any failure of either Party to require the other Party to comply
            with any provision of this Agreement will not be deemed a waiver of
            such provision or any other provision of this Agreement.

      D.    Each Party represents that its performance under this Agreement will
            be in full compliance with any and all applicable laws and
            regulations. GPO and Eligible Members shall comply with all
            applicable laws relating to the dispensing of Products purchased
            under this Agreement, including without limitation any state and/or
            local laws and regulations relating to drug product selection and
            consumer protection, and will fully advise consumers, if required,
            of the basis on which any product selection has been made, including
            the existence of this Agreement.

      E.    GPO, Eligible Members, Besse, and any other designated specialty
            distributors/wholesalers will not be deemed agents of Valera.

      F.    The Contract Prices and terms of this Agreement shall apply only to
            those facilities of Eligible Members located in the continental
            U.S., Alaska and Hawaii.

      G.    This Agreement will be construed in accordance with the laws of the
            State of Delaware with the exception of its choice of law
            principles. Any clause, section or paragraph of this Agreement which
            is determined by a court of competent jurisdiction to be illegal,
            invalid or unenforceable will be deemed severed from the remainder
            of the Agreement and will have no effect on the legality, validity,
            or enforceability of the remaining provisions.

      H.    Original copies of all notices hereunder will be hand-delivered,
            sent by first class mail or overnight mail to the addresses
            specified in this Agreement. Notice will be deemed given on the date
            of mailing.

      I.    GPO or Eligible Members may not assign the rights or obligations
            contained in this Agreement except with the prior written consent of
            Valera.

      J.    This Agreement and the Exhibits referenced herein represent the
            entire understanding between the parties with respect to the subject
            matter hereof, and supersedes any previous agreements entered into
            by the Parties relating to the subject matter hereof. Any amendment
            or renewal of this Agreement or any Exhibit shall be in writing and
            signed by both parties.

--------------------------------------------------------------------------------
Valera GPO Agreement for U.S. Urology   Page 4
<PAGE>
      K.    Execution of this Agreement by the Parties indicates acceptance of
            the terms and conditions herein on behalf of itself and on behalf of
            its members.

Each of the signatories represents that he/she is duly authorized to sign this
Agreement, and this Agreement is a binding obligation of the party on whose
behalf it is signed.

AGREED AND ACCEPTED:

      VALERA PHARMACEUTICALS, INC.

      By:    /s/ David S. Tierney
             -------------------------------

      Title: President and CEO
             ----------------------------

      Date:  3/18/2005
             -----------------------------

      INTERNATIONAL PHYSICIAN NETWORKS, L.L.C.

      By:    /s/ Anthony Corrao
             -------------------------------

      Title: President, GM IPN
             ----------------------------

      Date:  3-21-05
             -----------------------------

--------------------------------------------------------------------------------
Valera GPO Agreement for U.S. Urology   Page 5
<PAGE>
                                    EXHIBIT A

A.    PRODUCTS COVERED BY THIS AGREEMENT AND RELATED CONTRACT PRICE(1)

<TABLE>
<CAPTION>
                                                  Q1/05
                     VANTAS                   CONTRACT PRICE   DISCOUNT OF WAC
                     ------                   --------------   ---------------
<S>                                           <C>              <C>
      U.S. Urology Practices                        ****            ****
      US Bioservices Corporation                    ****            ****
</TABLE>

<TABLE>
<CAPTION>
                                                  Q2/05        DISCOUNT OF WAC
                     VANTAS                   CONTRACT PRICE
                     ------                   --------------   ---------------
<S>                                           <C>              <C>
      U.S. Urology Practices                        ****            ****
      U.S. Bioservices Corporation                  ****            ****
</TABLE>

--------
(1)  The parties will determine the Contract Price and related discounts for Q3
     and Q4 2005 upon the calculation and configuration of the Products Average
     Sales Price.

--------------------------------------------------------------------------------
Valera GPO Agreement for U.S. Urology   Page 6
<PAGE>
                                    EXHIBIT B

A.    ADMINISTRATIVE FEES

       GPO shall receive a **** administrative fee on aggregate sales of the
       Products to Eligible Members at the Contract Price.

       The fees provided for above shall be paid by Valera to GPO quarterly,
       within sixty- (60) days after each three- (3) month period during the
       term of this Agreement. Valera agrees to provide GPO with reasonable
       access to all materials and documents that may be necessary to ensure the
       accuracy of any fees paid hereunder.

B.    ADMINISTRATIVE ASSISTANCE

      GPO will provide Valera the following administrative assistance subject to
      the limitations set forth below:

      i.   Provide Eligible Member data at physician level on utilization
           (de-identified as to patient identity as required by law).

      ii.  Inform Eligible Members about the terms of this Agreement, including
           the distribution services available through Besse, and otherwise
           administer the terms of this Agreement on behalf of Valera.

      iii. Allow Valera representatives the opportunity to attend certain
           designated meetings of U.S. Urology Practices during the term
           of this Agreement.

--------------------------------------------------------------------------------
Valera GPO Agreement for U.S. Urology   Page 7
<PAGE>
                                  ATTACHMENT 1

<TABLE>
<CAPTION>
                                                                                  Designated
                                                                                   Specialty
          Clinic or Physician                                                   Distributor or
                 Office           DEA #           Address           Phone #    Wholesaler/Address
                 ------           -----           -------           -------    ------------------
<S>                               <C>             <C>               <C>        <C>

</TABLE>

--------------------------------------------------------------------------------
Valera GPO Agreement for U.S. Urology   Page 8

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