Document:

First Amendment to Credit Agreement

 Exhibit 10.12 
 FIRST AMENDMENT TO CREDIT AGREEMENT 
 THIS FIRST AMENDMENT TO
CREDIT AGREEMENT (this “Amendment”), dated as of January 27, 2011, is entered into by and among INFUSYSTEM HOLDINGS, INC., a Delaware corporation (“Holdings”), INFUSYSTEM, INC., a California corporation
(“InfuSystem”) and FIRST BIOMEDICAL, INC., a Kansas corporation (“FBI” and together with Holdings and InfuSystem, the “Borrowers” and each individually a “Borrower”), BANK OF
AMERICA, N.A. in its capacity as an Administrative Agent and as a Lender (“Agent”) and the other lenders party hereto (collectively, together with the Agent in its capacity as a Lender, the “Lenders”). 

WHEREAS, the Borrowers and the Agent and the Lenders are parties to that certain Credit Agreement dated as of June 15, 2010
(the “Existing Credit Agreement” and as such Existing Credit Agreement is amended by this Amendment, the “Amended Credit Agreement”); and 
 WHEREAS, the Borrowers, Agent and Lenders desire to amend the terms of the Existing Credit Agreement on the terms and conditions set forth in this Amendment. 

NOW, THEREFORE, in consideration of the premises and mutual agreements herein contained, the parties hereto agree as follows.

 SECTION 1 
 DEFINED TERMS 
 Capitalized terms used but not defined herein shall
have the meanings ascribed to such terms in the Existing Credit Agreement. 
 SECTION 2 

AMENDMENT TO EXISTING CREDIT AGREEMENT 
 Section 6.12(b) of the Existing Credit Agreement is hereby amended by deleting the Section in its entirety and substituting the following therefor: 

“(b) Fixed Charge Coverage Ratio. Maintain on a consolidated basis a Fixed Charge Coverage Ratio of at least
1.25:1:0. 
 This ratio will be calculated at the end of each Fiscal Quarter during the term of this Agreement commencing with
the Fiscal Quarter ended September 30, 2010, using the results of (i) with respect to the calculation for the Fiscal Quarter ended September 30, 2010, the three (3) month period then ended, (ii) with respect to the
calculation for the Fiscal Quarter ended December 31, 2010, the six (6) month period then ended, (iii) with respect to the calculation for the Fiscal Quarter ended March 31, 2011, the nine (9) month period then ended and
(iv) with respect to the calculation for the Fiscal Quarter ended June 30, 2011 and for the calculation as of each Fiscal Quarter thereafter, the twelve (12) month period then ended.” 

 
 SECTION 3 

REPRESENTATIONS AND WARRANTIES 
 Each Borrower hereby represents and warrants to the Agent and Lenders that: 

3.1 Due Authorization, etc. The execution and delivery by it of this Amendment and the performance by it of its obligations
under the Existing Credit Agreement are duly authorized by all necessary corporate action, do not require any filing or registration with or approval or consent of any governmental agency or authority, do not and will not conflict with, result in
any violation of or constitute any default under any provision of its certificate 

  
 First Amendment to Credit
Agreement 

 
or articles of incorporation, as applicable, or by-laws or those of any of its Subsidiaries or any material agreement or other document binding upon or applicable to it or any of its Subsidiaries
(or any of their respective properties) or any material law or governmental regulation or court decree or order applicable to it or any of its Subsidiaries, and will not result in or require the creation or imposition of any Lien in any of its
properties or the properties of any of its Subsidiaries pursuant to the provisions of any agreement binding upon or applicable to it or any of its Subsidiaries. 
 3.2 Validity. This Amendment has been duly executed and delivered by such Borrower and, together with the Existing Credit Agreement, are the legal, valid and binding obligations of such
Borrower, enforceable against such Borrower in accordance with their respective terms subject, as to enforcement only, to bankruptcy, insolvency, reorganization, moratorium or similar laws affecting the enforceability of the rights of creditors
generally. 
 3.3 Representations and Warranties. The representations and warranties contained in Article V of the
Existing Credit Agreement are true and correct on the date of this Amendment in all material respects (except for those that are qualified by “materiality” or “Material Adverse Effect”, in which case such representations and
warranties shall have been true and correct in all respects), except to the extent (a) that such representations and warranties solely relate to an earlier date or (b) have been changed by circumstances permitted by the Existing Credit
Agreement. 
 SECTION 4 
 CONDITIONS PRECEDENT 
 The amendment to the Existing Credit
Agreement set forth in Section 2 of this Amendment shall become effective upon satisfaction of all of the following conditions precedent: 
 4.1 Receipt of Documents. Agent shall have received a counterpart original of this Amendment duly executed by Borrowers and the Lenders referenced on the signature page hereto. 

4.2 Other Conditions. No Event of Default or Default shall have occurred and be continuing. 

SECTION 5 

MISCELLANEOUS 
 5.1 Warranties and Absence of Defaults. In order to induce the Agent and Lenders to enter into this Amendment, Borrowers hereby warrant to the Agent and each Lender, as of the date of the
actual execution of this Amendment (a) no Event of Default or Default has occurred which is continuing as of such date and (b) the representations and warranties in Section 3 of this Amendment are true and correct. 

5.2 Documents Remain in Effect. Except as amended and modified by this Amendment, the Existing Credit Agreement and the
other documents executed pursuant to the Existing Credit Agreement remain in full force and effect and each Borrower hereby ratifies, adopts and confirms its representations, warranties, agreements and covenants contained in, and obligations and
liabilities under, the Existing Credit Agreement and the other documents executed pursuant to the Existing Credit Agreement. 

5.3 Reference to Loan Agreement. On and after the effective date of this Amendment, each reference in the Existing Credit
Agreement to “this Agreement,” “hereunder,” “hereof,” “herein” or words of like import, and each reference to the “Loan Agreement” in any Loan Documents, or other agreements, documents or other
instruments executed and delivered pursuant to the Existing Credit Agreement, shall mean and be a reference to the Amended Credit Agreement. 

  
 First Amendment to Credit
Agreement 

 5.4 Headings. Headings used in this Amendment are for convenience of reference
only, and shall not affect the construction of this Amendment. 
 5.5 Counterparts. This Amendment may be executed
in any number of counterparts, and by the parties hereto on the same or separate counterparts, and each such counterpart, when executed and delivered, shall be deemed to be an original, but all such counterparts shall together constitute but one and
the same Amendment. 
 5.6 Intentionally Omitted. 

5.7 Governing Law. This Amendment shall be a contract made under and governed by the internal laws of the State of
Illinois. Wherever possible, each provision of this Amendment shall be interpreted in such manner as to be effective and valid under applicable laws, but if any provision of this Amendment shall be prohibited by or invalid under such laws, such
provisions shall be ineffective only to the extent of such prohibition or invalidity, without invalidating the remainder of such provision or the remaining provisions of this Amendment. 

5.8 Successors. This Amendment shall be binding upon Borrowers, Agent, each Lender and their respective successors and
assigns, and shall inure to the benefit of Borrowers, Agent, each Lender and the successors and assigns of the Agent and such Lender. 

  
 First Amendment to Credit
Agreement 

 IN WITNESS WHEREOF, the parties hereto have caused this Amendment to be executed by
their respective officers thereunto duly authorized and delivered at Chicago, Illinois as of the date first above written. 

BORROWERS: 
  

									
	INFUSYSTEM HOLDINGS, INC.	 		 	FIRST BIOMEDICAL, INC.
					
	By:	 	 /s/ James M. Froisland
	 		 	By:	 	 /s/ James M. Froisland

	Name:	 	James M. Froisland	 		 	Name: 	 	James M. Froisland
	Title:	 	Chief Financial Officer	 		 	Title:	 	Chief Financial Officer
			
	INFUSYSTEM, INC.	 		 	
					
	By:	 	 /s/ James M. Froisland
	 		 		 	
	Name:	 	James M. Froisland	 		 		 	
	Title:	 	Chief Financial Officer	 		 		 	
				
	AGENTS AND LENDERS:	 		 		 	
				
	 BANK OF AMERICA, N.A., in its
 capacity as Administrative Agent,
	 		 		 	
					
	By:	 	 /s/ Rosanne Parcill
	 		 		 	
	Name:	 	Rosanne Parcill	 		 		 	
	Title:	 	Assistant Vice-President	 		 		 	
				
	 BANK OF AMERICA, N.A., in its
 capacity as a Lender
	 		 		 	
					
	By:	 	 /s/ Sophia Love
	 		 		 	
	Name:	 	Sophia Love	 		 		 	
	Title:	 	Senior Vice President	 		 		 	
				
	KEYBANK NATIONAL ASSOCIATION, in its capacity as a Lender	 		 		 	
					
	By:	 	 /s/ Thomas J. Purcell
	 		 		 	
	Name: 	 	Thomas J. Purcell	 		 		 	
	Title:	 	Senior Vice-President	 		 		 	

  
 First Amendment to Credit
AgreementThird Amendment to Credit Agreement

 Exhibit 10.14 
 THIRD AMENDMENT TO CREDIT AGREEMENT 
 THIS THIRD AMENDMENT TO
CREDIT AGREEMENT (this “Amendment”), dated as of May 20, 2011, is entered into by and among INFUSYSTEM HOLDINGS, INC., a Delaware corporation (“Holdings”), INFUSYSTEM, INC., a California corporation
(“InfuSystem”) and FIRST BIOMEDICAL, INC., a Kansas corporation (“FBI” and together with Holdings and InfuSystem, the “Borrowers” and each individually a “Borrower”), BANK OF
AMERICA, N.A. in its capacity as an Administrative Agent and as a Lender (“Agent”) and the other lenders party hereto (collectively, together with the Agent in its capacity as a Lender, the “Lenders”). 

WHEREAS, the Borrowers and the Agent and the Lenders are parties to that certain Credit Agreement dated as of June 15, 2010
as amended by (i) that certain First Amendment to Credit Agreement dated as of January 27, 2011 and (ii) that certain Second Amendment to Credit Agreement dated as of April 1, 2011 (the “Existing Credit Agreement”
and as such Existing Credit Agreement is amended by this Amendment, the “Amended Credit Agreement”); 

WHEREAS, the Borrowers have requested that the Agent and the Lenders modify the Existing Credit Agreement in certain respects and
the Agent and Lenders have agreed to amend the terms of the Existing Credit Agreement on the terms and conditions set forth in this Amendment. 
 NOW, THEREFORE, in consideration of the premises and mutual agreements herein contained, the parties hereto agree as follows. 

SECTION 1 

DEFINED TERMS 
 Capitalized terms used but not defined herein shall have the meanings ascribed to such terms in the Existing Credit Agreement. 
 SECTION 2 
 AMENDMENT TO EXISTING CREDIT AGREEMENT 

The definition of “EBITDA” contained in Section 1.01 of the Existing Credit Agreement is hereby amended by deleting the
definition in its entirety and substituting the following therefor: 
 ““EBITDA” means,
with respect to any Person, during any period, net income, less income or plus loss from discontinued operations and extraordinary items, plus, to the extent deducted in computing net income and without duplication, the sum of (i) income
taxes, (ii) Interest Charges, (iii) depreciation, (iv) depletion and amortization, (v) non-cash compensation expense, (vi) all other non-cash charges, provided that, for purposes of this subclause (vi), any non-cash charges
or losses shall be treated as cash charges or losses in any subsequent period during which cash disbursements attributable thereto are made (but excluding, for the avoidance of doubt, amortization of a prepaid cash item that was paid in a prior
period), (vii) out of pocket expenses incurred in connection with the FBI Purchase, this Agreement and the other Loan Documents in an amount not to exceed $1,000,000, (viii) charges in connection with severance payments made during such
period to the extent such charges are acceptable to the Required Lenders; plus or minus (as applicable) any non-cash losses or gains from unrealized changes in the fair market value of warrants, Swap Contracts and other derivatives,
which gains or losses would be reflected on the Consolidated statement of operations of Holdings and its Subsidiaries plus (ix) with respect to EBITDA of the Borrowers for the fiscal quarter ended September 30, 2009, an aggregate
amount equal to $877,285.00 in respect of severance payments made by the Borrowers during such fiscal quarter plus (x) with respect to EBITDA of the Borrowers for the fiscal 

 
quarter ended June 30, 2011, an aggregate amount of up to $1,900,000.00 in respect of one-time tax reimbursement compensation payments by Holdings to certain of its directors to the extent
such payments were accrued during the quarter ended December 31, 2010 and paid in cash during the quarter ended June 30, 2011.” 
 SECTION 3 
 REPRESENTATIONS AND WARRANTIES 

Each Borrower hereby represents and warrants to the Agent and Lenders that: 

3.1 Due Authorization, etc. The execution and delivery by it of this Amendment and the performance by it of its obligations
under the Existing Credit Agreement are duly authorized by all necessary corporate action, do not require any filing or registration with or approval or consent of any governmental agency or authority, do not and will not conflict with, result in
any violation of or constitute any default under any provision of its certificate or articles of incorporation, as applicable, or by-laws or those of any of its Subsidiaries or any material agreement or other document binding upon or applicable to
it or any of its Subsidiaries (or any of their respective properties) or any material law or governmental regulation or court decree or order applicable to it or any of its Subsidiaries, and will not result in or require the creation or imposition
of any Lien in any of its properties or the properties of any of its Subsidiaries pursuant to the provisions of any agreement binding upon or applicable to it or any of its Subsidiaries. 

3.2 Validity. This Amendment has been duly executed and delivered by such Borrower and, together with the Existing Credit
Agreement, are the legal, valid and binding obligations of such Borrower, enforceable against such Borrower in accordance with their respective terms subject, as to enforcement only, to bankruptcy, insolvency, reorganization, moratorium or similar
laws affecting the enforceability of the rights of creditors generally. 
 3.3 Representations and Warranties. The
representations and warranties contained in Article V of the Existing Credit Agreement are true and correct on the date of this Amendment in all material respects (except for those that are qualified by “materiality” or “Material
Adverse Effect”, in which case such representations and warranties shall have been true and correct in all respects), except to the extent (a) that such representations and warranties solely relate to an earlier date or (b) have been
changed by circumstances permitted by the Existing Credit Agreement. 
 SECTION 4 

CONDITIONS PRECEDENT 
 The amendment to the Existing Credit Agreement set forth in Section 2 of this Amendment shall become effective upon satisfaction of all of the following conditions precedent: 

4.1 Receipt of Documents. Agent shall have received all of the following, each in form and substance satisfactory to Agent:

 (a) Amendment. A counterpart original of this Amendment duly executed by Borrowers. 

(b) Secretary’s Certificate. A certificate of the secretary of each Borrower dated the date hereof or such
other date as shall be acceptable to Agent, substantially in the form of Exhibit A to this Amendment. 
 4.2 Other
Conditions. No Event of Default or Default shall have occurred and be continuing. 
 SECTION 5 

MISCELLANEOUS 
 5.1 Warranties and Absence of Defaults. In order to induce the Agent and Lenders to enter into this Amendment, Borrowers hereby warrant to the Agent and each Lender, as of the date of the
actual execution of 

 
this Amendment (a) no Event of Default or Default has occurred which is continuing as of such date and (b) the representations and warranties in Section 3 of this Amendment are
true and correct. 
 5.2 Documents Remain in Effect. Except as amended and modified by this Amendment, the
Existing Credit Agreement and the other documents executed pursuant to the Existing Credit Agreement remain in full force and effect and each Borrower hereby ratifies, adopts and confirms its representations, warranties, agreements and covenants
contained in, and obligations and liabilities under, the Existing Credit Agreement and the other documents executed pursuant to the Existing Credit Agreement. 
 5.3 Reference to Loan Agreement. On and after the effective date of this Amendment, each reference in the Existing Credit Agreement to “this Agreement,” “hereunder,”
“hereof,” “herein” or words of like import, and each reference to the “Loan Agreement” in any Loan Documents, or other agreements, documents or other instruments executed and delivered pursuant to the Existing Credit
Agreement, shall mean and be a reference to the Amended Credit Agreement. 
 5.4 Headings. Headings used in this
Amendment are for convenience of reference only, and shall not affect the construction of this Amendment. 
 5.5
Counterparts. This Amendment may be executed in any number of counterparts, and by the parties hereto on the same or separate counterparts, and each such counterpart, when executed and delivered, shall be deemed to be an original, but all
such counterparts shall together constitute but one and the same Amendment. 
 5.6 Expenses. Borrowers agree, jointly and
severally, to pay on demand all reasonable out-of-pocket costs and expenses of Agent (including reasonable fees, charges and disbursements of Agent’s attorneys) in connection with the preparation, negotiation, execution, delivery and
administration of this Amendment and all other instruments or documents provided for herein or delivered or to be delivered hereunder or in connection herewith. In addition, Borrowers agree, jointly and severally, to pay, and save Agent and each
Lender harmless from all liability for, any stamp or other taxes which may be payable in connection with the execution or delivery of this Amendment, the borrowings under the Amended Credit Agreement, and the execution and delivery of any
instruments or documents provided for herein or delivered or to be delivered hereunder or in connection herewith, in each case to the same extent required under the Credit Agreement. All obligations provided in this Section 6.6 shall survive
any termination of this Amendment or the Amended Credit Agreement. 
 5.7 Governing Law. This Amendment shall be a
contract made under and governed by the internal laws of the State of Illinois. Wherever possible, each provision of this Amendment shall be interpreted in such manner as to be effective and valid under applicable laws, but if any provision of this
Amendment shall be prohibited by or invalid under such laws, such provisions shall be ineffective only to the extent of such prohibition or invalidity, without invalidating the remainder of such provision or the remaining provisions of this
Amendment. 
 5.8 Successors. This Amendment shall be binding upon Borrowers, Agent, each Lender and their
respective successors and assigns, and shall inure to the benefit of Borrowers, Agent, each Lender and the successors and assigns of the Agent and such Lender. 
 IN WITNESS WHEREOF, the parties hereto have caused this Amendment to be executed by their respective officers thereunto duly authorized and delivered at Chicago, Illinois as of the date first above
written. 

 BORROWERS: 
  

									
	INFUSYSTEM HOLDINGS, INC.	 		 	FIRST BIOMEDICAL, INC.
					
	By:	 	 /s/ JAMES FROISLAND
	 		 	By:	 	 /s/ JAMES FROISLAND

	Name:	 	James Froisland	 		 	Name: 	 	James Froisland
	Title:	 	CFO	 		 	Title:	 	CFO
			
	INFUSYSTEM, INC.	 		 	
					
	By:	 	 /s/ JAMES FROISLAND
	 		 		 	
	Name:	 	James Froisland	 		 		 	
	Title:	 	CFO	 		 		 	
				
	AGENTS AND LENDERS:	 		 		 	
				
	 BANK OF AMERICA, N.A., in its
 capacity as Administrative Agent,
	 		 		 	
					
	By:	 	 /s/ ROSANNE PARSILL
	 		 		 	
	Name:	 	Rosanne Parsill	 		 		 	
	Title:	 	Vice President	 		 		 	
				
	 BANK OF AMERICA, N.A., in its
 capacity as a Lender
	 		 		 	
					
	By:	 	 /s/ SOPHIA LOVE
	 		 		 	
	Name:	 	Sophia Love	 		 		 	
	Title:	 	Senior Vice President	 		 		 	
				
	 KEYBANK NATIONAL ASSOCIATION, in its
 capacity as a Lender
	 		 		 	
					
	By:	 	 /s/ SUKANYA V. RAJ
	 		 		 	
	Name: 	 	Sukanya V. Raj	 		 		 	
	Title:	 	Vice President & Portfolio Manager	 		 		 	

 SECRETARY’S CERTIFICATE 

 

	To:	Bank of America, N.A., as administrative agent 

 This Certificate is being furnished pursuant to Section 4.1(b) of that certain Third Amendment to Credit Agreement (the “Amendment”), dated as of May 20, 2011 by and among INFUSYSTEM
HOLDINGS, INC., a Delaware corporation (“Holdings”), INFUSYSTEM, INC., a California corporation (“InfuSystem”) and FIRST BIOMEDICAL, INC., a Kansas corporation (“FBI” and together with Holdings and
InfuSystem, the “Borrowers” and each individually a “Borrower”), BANK OF AMERICA, N.A. in its capacity as an Administrative Agent and as a Lender (“Agent”) and the other lenders party thereto
(collectively, together with the Agent in its capacity as a Lender, the “Lenders”), which amends that certain Credit Agreement dated as of June 15, 2010 as amended by (i) that certain First Amendment to Credit Agreement
dated as of January 27, 2011 and (ii) that certain Second Amendment to Credit Agreement dated as of April 1, 2011 (the “Existing Credit Agreement” and as the Existing Credit Agreement is amended and modified by the
Amendment, the “Amended Credit Agreement”). Capitalized terms used but not defined herein shall have the meanings ascribed to such terms in the Amendment. 
 The undersigned, Secretary of each Borrower, hereby certifies on behalf of such Borrower, that: 
 1. Such Borrower has adopted resolutions sufficient to authorize the proper officers of such Borrower to execute and deliver the Amendment in the name and on behalf of such Borrower, and each of them is
authorized to cause such Borrower to borrow funds under the Amended Credit Agreement. Such resolutions have not been rescinded or amended and are in full force and effect on and as of the date hereof. 

2. Other than the resolutions referred to in clause 1 above, there is no corporate action, consent or governmental approval required for
the execution, delivery and performance by such Borrower of the Amendment or any other document, instrument or agreement contemplated by the Amendment. 
 3. The following named persons were duly elected to, and are validly acting in, the offices listed opposite each of their names and are authorized to execute on behalf of and in the name of each Borrower
the Amendment and any and all other agreements, instruments or documents contemplated by the Amendment, and their respective signatures set forth below are their genuine signatures. 

 

					
	 Name
	  	 Title
	  	 Signature

			
	James Froisland	  	Chief Financial Officer	  	/s/ James M. Froisland
			
	Janet Skonieczny	  	Secretary	  	/s/ Janet Skonieczny
			
	Sean McDevitt	  	Chief Executive Officer	  	/s/ Sean McDevitt

 4. I know of no proceeding for the dissolution or liquidation of any Borrower or threatening
the existence of any Borrower. 
 5. There have been no amendments to the Articles or Certificates of Incorporation or to the
By-laws of any Borrower since the date of the certified copies thereof provided to you in connection with the execution of the Existing Credit Agreement. 
 6. Agent and the Lenders may rely on this Certificate until advised by a like certificate of any changes herein. 
 IN WITNESS WHEREOF, I have executed this Certificate on May 20, 2011. 
  

			
	By:	 	 /s/ Janet Skonieczny

	Name:	 	Janet Skonieczny
	Title:	 	Secretary

 I, the undersigned, Chief Executive Officer of each Borrower, DO HEREBY CERTIFY that Janet
Skonieczny is the duly elected and qualified Secretary of such Borrower, and the signature above is a genuine signature. 

WITNESS my hand this 20 day of May, 2011. 
  

			
	By:	 	 /s/ Sean McDevitt

	Name:	 	Sean McDevitt
	Title:	 	Chief Executive Officer

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