Document:

Second Amendment of Lease dated as of March 7, 2007 from BHX, LLC

 Exhibit 10.1 
 SECOND AMENDMENT OF LEASE 
 THIS SECOND AMENDMENT OF LEASE (this “Amendment”) is
made as of the 7th day of March, 2007, by BHX, LLC, a Massachusetts limited liability company, as Trustee of 3 Forbes Realty Trust, a Massachusetts nominee trust (“Landlord”), and ANTIGENICS, INC., a Delaware corporation
(“Tenant”). 
 Recitals 
 A. Landlord and Tenant are parties to a Lease dated December 6, 2002, as amended by a First Amendment of Lease dated August 15, 2003 (as so amended, the “Lease”), pursuant to which Landlord
leased to Tenant space in the building commonly known as 3 Forbes Road, Lexington, Massachusetts. All capitalized terms used in this Amendment which are defined in the Lease and not otherwise defined in this Amendment shall have the meanings given
in the Lease. 
 B. The parties desire to enter into this Amendment to give Landlord an option to eliminate the First Additional Premises
and/or the Second Additional Premises from the Lease as provided below. 
 Statement of Amendment 
 For good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, Landlord and Tenant hereby agree as follows:

 1. Landlord’s Option to Eliminate First Additional Premises and Second Additional Premises. Tenant grants to Landlord an option
(the “Reduction Option”) to eliminate the First Additional Premises and/or the Second Additional Premises from the Lease, which Reduction Option shall be exercised, if at all, by written notice of exercise given by Landlord to
Tenant not later than September 30, 2007. In any notice of exercise of the Reduction Option, Landlord shall specify (i) whether Landlord is exercising the Reduction Option with respect to the First Additional Premises only, the Second
Additional Premises only, or both the First Additional Premises and the Second Additional Premises (as so specified, the “Eliminated Premises”) (the Premises, less the Eliminated Premises, being called the “Reduced
Premises”), and (ii) the amount, if any, which Landlord requires Tenant to pay to Landlord in respect of costs incurred or to be incurred by Landlord in connection with the Reduction Option, including leasing commissions,
attorneys’ fees and demising costs (such amount being called the “Reduction Fee”). If Landlord timely exercises the Reduction Option and specifies a Reduction Fee, Tenant shall, within ten (10) Business Days after receipt
of Landlord’s notice of exercise, give written notice to Landlord either accepting or rejecting the Reduction Fee. If Tenant fails to respond within such ten (10) Business Day period, Tenant shall be deemed to have accepted the Reduction
Fee. Tenant has the right, in its sole discretion, to reject any Reduction Fee in excess of one dollar ($1.00). If Tenant rejects the Reduction Fee within such ten (10) Business Day period, then, unless Landlord and Tenant agree on a Reduction
Fee within such ten (10) Business Day period, Landlord shall be deemed to have withdrawn the exercise of the Reduction Option. If Landlord timely exercises the Reduction Option without requiring a Reduction Fee, or if Landlord timely exercises
the Reduction Option and requires a Reduction Fee which is accepted by Tenant, then: 
  

	 	(a)	within thirty (30) days after Tenant receives notice of such exercise (if the notice does not specify a Reduction Fee) or accepts the Reduction Fee (if the notice specifies a
Reduction Fee), Tenant shall surrender the Eliminated Premises in the condition required upon termination as provided in Section 7.4 of the Lease (the “Elimination Date”); 

  

	 	(b)	the Eliminated Premises shall be eliminated from the Lease effective as of the Elimination Date, and Tenant shall be considered to be holding over if it has not delivered the
Eliminated Premises in the condition required upon termination as provided in Section 7.4 of the Lease as of the Elimination Date; 

	 	(c)	Tenant’s Share, for purposes of determining the Additional Rent in respect of Taxes, Insurance Costs and Operating Costs, shall remain at 100% until the Elimination Date; and

  

	 	(d)	the total Base Rent shall be unchanged from the amounts provided for in Item 9 of the Summary of Basic Terms until the Elimination Date. 

 On or promptly after the Elimination Date, Landlord and Tenant shall enter into an amendment of the Lease to confirm the Elimination Date and make such modifications as
are necessary to reflect the elimination of the Eliminated Premises from the Lease and the provisions of clauses (c) and (d) above. 
 2. Marketing Costs. Contemporaneously herewith, Landlord is entering into an agreement (the “Brokerage Agreement”) with Cushman & Wakefield (“Broker”), pursuant to which Landlord is engaging
Broker to attempt to lease the First Additional Premises and the Second Additional Premises. Tenant understands that Landlord will incur out-of-pocket costs in attempting to market the First Additional Premises and the Second Additional Premises,
and agrees to pay or reimburse Landlord for such actual costs incurred or paid, up to a maximum of $10,000, within thirty (30) days of receipt of an invoice and supporting documentation in reasonable detail, whether or not Landlord exercises
the Reduction Option. 
 3. Additional Requirements. Within ten (10) Business Days after the date of this Amendment, Tenant shall
broom clean and wash and shine the floors of the First Additional Premises and Second Additional Premises and neatly organize its personal property presently located therein to specific, limited areas therein to minimize the amount of space in which
such personal property is stored and the visibility of such personal property to facilitate Broker’s showings of the First Additional Premises and Second Additional Premises to potential third party tenants. Promptly after the date of this
Amendment, Landlord shall arrange to re-key the doors to the First Additional Premises and the Second Additional Premises and provide Tenant with a copy of the new key(s) and shall install a lock box to enable Broker to show such space without
making prior arrangements with Tenant, and Landlord and Broker shall have the right of access to the First Additional Premises and the Second Additional Premises for such purpose. Tenant has arranged for temporary heat to the First Additional
Premises and the Second Additional Premises, and shall maintain such temporary heat and monitor the First Additional Premises and the Second Additional Premises to avoid the risk of frozen pipes or other damage resulting from lack of heat.

 4. Inconsistencies; Continuing Effect of Lease. To the extent that the provisions of this Amendment are inconsistent with the
provisions of the Lease, the provisions of this Amendment will control and the Lease will be deemed to be amended hereby. Except as amended by this Amendment, the provisions of the Lease remain in full force and effect. 
  

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 5. Multiple Counterparts. This Amendment may be executed in multiple counterparts, each of which
will be an original, but all of which, taken together, will constitute one and the same Amendment. 
 IN WITNESS WHEREOF, Landlord and Tenant
have executed this Amendment as of the date first set forth above. 
  

			
	BXH, LLC, as Trustee of 3 Forbes Realty Trust
		
	By:	 	 /s/ Eric D. Schlager

	Name:	 	Eric D. Schlager
	Title:	 	Member
	
	ANTIGENICS, INC.
		
	By:	 	 /s/ Garo Armen

	Name:	 	Garo Armen
	Title:	 	CEO

  

 -3-Amendment No. 3 to Refinancing Credit Agreement

 Exhibit 10.1 
 AMENDMENT NO. 3 TO REFINANCING CREDIT AGREEMENT 
 THIS AMENDMENT NO. 3 (this
“Amendment”) is dated as of February 6, 2007, and amends and renews the Refinancing Credit Agreement, dated as of January 12, 2004, by and among WESTINGHOUSE AIR BRAKE TECHNOLOGIES CORPORATION, a Delaware corporation
(the “Company”), each of the other Loan Parties from time to time party thereto (the “Loan Parties”), the financial institutions that are or may from time to time become parties thereto (together with their
respective successors and assigns, the “Lenders”), and LASALLE BANK NATIONAL ASSOCIATION, as bookrunner, lead arranger, and an Issuing Lender and as administrative agent for the Lenders (the “Administrative
Agent”), JPMORGAN CHASE BANK, as syndication agent and co-arranger, THE BANK OF NEW YORK, CITIZENS BANK OF PENNSYLVANIA and NATIONAL CITY BANK OF PENNSYLVANIA, as co-documentation agents, and BANK OF NOVA
SCOTIA, PNC BANK, NATIONAL ASSOCIATION, and BANK OF TOKYO-MITSUBISHI UFJ TRUST COMPANY, as Senior Managing Agents, and JPMORGAN CHASE BANK (as assignee of Chase Manhattan Bank USA, N.A.), as an Issuing Lender
(as amended by Amendment No. 1 and Amendment No. 2, among the parties hereto, respectively dated as of July 13, 2005, and November 15, 2005, the “Credit Agreement”). 
 BACKGROUND 
 The parties hereto desire to amend and renew the Credit
Agreement to modify limitations on acquisitions. 
 Subject to the terms and conditions set forth below, the parties hereto desire to amend
and renew the Credit Agreement as set forth herein. 
 OPERATIVE PROVISIONS 
 NOW THEREFORE, the parties hereto, in consideration of their mutual covenants and agreements herein contained, incorporating the above-defined
terms herein, and intending to be legally bound hereby agree as follows: 
 Article I 
 Consent and Amendments 
 1.01 Defined Terms; References. Terms not otherwise defined in this Amendment (including in the preamble and the Background provisions set forth above) shall have the respective meanings ascribed to them in the
Credit Agreement. As used in this Amendment, “including” is not a term of limitation and means “including without limitation.” Each reference to “hereof,” “hereunder,”
“herein,” and “hereby” and similar references contained in the Credit Agreement and each reference to “this Agreement” and similar references contained in the Credit Agreement shall, on and after
the effective date hereof, refer to the Credit Agreement as amended hereby. 

 1.02 Amendment of Credit Agreement. The Credit Agreement is hereby amended as
set forth below. 
 (a) Amendment to Section 11.5. Clause (C) of Section 11.5(e) is hereby deleted and replaced in its entirety by the
following: 
 “(C) (x) the aggregate consideration to be paid by the Loan Parties (including any Debt assumed or issued
in connection therewith, the amount thereof to be calculated in accordance with GAAP) in connection with such Acquisition is less than $100,000,000, or (y) the aggregate consideration to be paid by the Loan Parties (including any Debt assumed or
issued in connection therewith, the amount thereof to be calculated in accordance with GAAP) in connection with such Acquisition is equal to or greater than $100,000,000 and the Total Debt to EBITDA Ratio as of the last day of the most recent
Computation Period and on a pro forma basis after giving effect to such Acquisition does not exceed 2.00 to 1.00;” 
 (b) Amendment to
Section 11.11. Section 11.11 is hereby amended by replacing Clauses (a) and (h) thereof in their entirety with the following: 
 “(a) contributions by the Company to the capital of any Wholly-Owned Subsidiary, or by any Subsidiary to the capital of any other domestic Wholly-Owned Subsidiary, so long as the recipient of any such capital contribution has
guaranteed the Obligations, in each case in accordance with Section 10.10;” 
 “(h) in addition to the Investments
permitted by other clauses of this Section 11.11 (including Investments permitted by Clause (j) below), Investments to or in Ventures or non-domestic Subsidiaries of the Company in an aggregate amount at any time of calculation not in excess of
$65,000,000;” 
 Article II 
 Representations and Warranties 
 As of the date hereof, the Loan Parties, jointly and severally, represent and
warrant to the Administrative Agent and each of the Lenders as follows: 
 2.01 Authorization. The execution and
delivery by the Loan Parties of this Amendment, the consummation by the Loan Parties of the transactions contemplated by the Credit Agreement as amended hereby, and the performance by each Loan Party of its respective obligations hereunder and
thereunder have been duly authorized by all necessary corporate proceedings on the part of each Loan Party. On the date of its execution hereof, each Loan Party has no set-offs, claims, defenses, counterclaims, causes of action, or deductions of any
nature against any of the Obligations. 
 2.02 Valid and Binding. This Amendment has been duly and validly
executed and delivered by each Loan Party and constitutes, and the Credit Agreement as amended and renewed hereby constitutes, the legal, valid and binding obligations of each Loan Party enforceable in accordance with the terms hereof and thereof,
except as the enforceability of this Amendment or the Credit Agreement as amended and renewed hereby may be limited by bankruptcy, insolvency or other similar laws of general application affecting the enforcement of creditors’ rights or by
general principles of equity limiting the availability of equitable remedies. The Credit Agreement as amended and renewed hereby is the “Credit Agreement” as such term is used in the Permitted Note Indenture. 
  

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 2.03 No Conflicts. Neither the execution and delivery of this Amendment nor
the consummation and performance of the transactions contemplated hereby or by the Credit Agreement as amended hereby nor compliance with the terms and provisions hereof or of the Credit Agreement as amended hereby, by any of the Loan Parties, will
(a) violate any Law, (b) conflict with or result in a breach of or a default under the articles or certificate of incorporation or bylaws or similar organizational documents of any Loan Party or any material agreement or instrument (including the
Permitted Note Indenture) to which any Loan Party is a party or by which any Loan Party or any of their respective properties (now owned or hereafter acquired) may be subject or bound, (c) require any consent or approval of any Person (including any
trustee for, or other party to or beneficiary of, the Permitted Note Indenture) or require a mandatory prepayment or any other payment under the terms of any material agreement or instrument (including the Permitted Note Indenture) to which any Loan
Party is a party or by which any Loan Party or any of their respective properties (now owned or hereafter acquired) may be subject or bound, (d) result in the creation or imposition of any Lien upon any property (now owned or hereafter acquired) of
any Loan Party, or (e) require any authorization, consent, approval, license, permit, exemption or other action by, or any registration, qualification, designation, declaration or filing with, any Official Body. 
 2.04 No Defaults. After giving effect to this Amendment and the consents made herein: (i) no Event of Default under and as
defined in the Credit Agreement has occurred and is continuing, and (ii) the representations and warranties of each of Company and the other Loan Parties contained in the Credit Agreement and the other Loan Documents are true and correct on and as
of the date hereof with the same force and effect as though made on such date, except to the extent that any such representation or warranty expressly relates solely to a previous date. 
 Article III 
 Effect, Effectiveness, Consent of Guarantors

 3.01 Effectiveness. This Amendment shall become effective as of the last date (such date being
referred to herein as the “Effective Date”) on which: 
 (a) The Administrative Agent shall have received from the Company,
each of the other Loan Parties, and each of the Required Lenders a counterpart hereof signed by such party or facsimile or other written or electronic confirmation (in form satisfactory to Administrative Agent) that such party has signed a
counterpart hereof; 
 (b) Each of the Loan Parties shall have delivered to the Agent a certificate signed by the Secretary or Assistant
Secretary of such Loan Party certifying as appropriate as to (a) authorization of such Loan Party to enter into the transactions contemplated by this Amendment, and (b) the names of the officers of such Loan Party authorized to execute this
Amendment and, if not previously provided, the true signatures of such officers, on which the Agent and each Bank may conclusively rely. 
 3.02 Amendment. As of the Effective Date, the Credit Agreement is hereby amended and renewed in accordance with the terms hereof, and this Amendment and the Credit Agreement shall hereafter be one agreement and
any reference to the Credit Agreement in any document, instrument, or agreement shall hereafter mean and include the Credit Agreement as amended and renewed hereby. In the event of irreconcilable inconsistency between the terms or provisions hereof
and the terms or provisions of the Credit Agreement, the terms and provisions hereof shall control and amend any such irreconcilably inconsistent provisions of the Credit Agreement. 
  

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 3.03 Joinder of Guarantors. Each of the Loan Parties hereby joins in this
Amendment to evidence its consent hereto, and each of the Loan Parties hereby reaffirms its obligations set forth in the Credit Agreement, as hereby amended and renewed, and in each Guaranty Agreement and each other Loan Document given by it in
connection therewith. 
 Article IV 
 Miscellaneous 
 4.01 Credit Agreement. Except as amended by the provisions hereof, the
Credit Agreement and all other Loan Documents shall remain in full force and effect and are hereby ratified and confirmed by the parties hereto. 
 4.02 Counterparts, Telecopy Signatures. This Amendment may be signed in any number of counterparts each of which shall be deemed an original, but all of which together shall constitute one and the same
instrument; and, delivery of executed signature pages hereof by telecopy transmission, or other electronic transmission in .pdf or similar format, from one party to another shall constitute effective and binding execution and delivery of this
Amendment by such party. 
 4.03 Governing Law. This Amendment shall be governed by and construed and enforced in
accordance with the laws of the Commonwealth of Pennsylvania without regard to its conflict of laws principles. 
 4.04
Severability. If any provision of this Amendment, or the application thereof to any party hereto, shall be held invalid or unenforceable, such invalidity or unenforceability shall not affect any other provisions or applications of this
Amendment which can be given effect without the invalid and unenforceable provision or application, and to this end the parties hereto agree that the provisions of this Amendment are and shall be severable. 
 4.05 Costs, Expenses. The Company shall pay all costs, expenses (including reasonable legal fees of counsel to Agent), and
disbursements of (i) Agent relating to the preparation and execution of this Amendment, and (ii) the Banks and Agent relating to the enforcement of and collection under this Amendment. 
 4.06 Lenders’ Consent. Each of the Required Lenders, by its execution hereof, hereby consents to this Amendment pursuant
Section 15.1 of the Credit Agreement. 
  

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 IN WITNESS WHEREOF, the parties hereto, by their officers thereunto duly authorized, have executed this
Amendment as of the day and year first above written. 
 [Signature Pages Omitted]

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