Document:

Form of indemnification agreement

 EXHIBIT 10.19 
 INDEMNITY AGREEMENT 
 THIS
INDEMNITY AGREEMENT (this “Agreement”) dated as of January 1, 2010, is made by and between World Heart Corporation, a Delaware corporation (the “Company”), and
                        (“Indemnitee”). 

RECITALS 
 A. The Company desires to attract and retain the services of highly qualified individuals as directors, officers, employees and agents. 

B. The Company’s bylaws (the “Bylaws”) require that the Company indemnify its directors, and
empowers the Company to indemnify its officers, employees and agents, as authorized by the Delaware General Corporation Law, as amended (the “Code”), under which the Company is organized and such Bylaws expressly provide that the
indemnification provided therein is not exclusive and contemplates that the Company may enter into separate agreements with its directors, officers and other persons to set forth specific indemnification provisions. 

C. Indemnitee does not regard the protection currently provided by applicable law, the Company’s governing
documents and available insurance as adequate under the present circumstances, and the Company has determined that Indemnitee and other directors, officers, employees and agents of the Company may not be willing to serve or continue to serve in such
capacities without additional protection. 
 D. The Company desires and has requested Indemnitee to serve
or continue to serve as a director, officer, employee or agent of the Company, as the case may be, and has proffered this Agreement to Indemnitee as an additional inducement to serve in such capacity. 

E. Indemnitee is willing to serve, or to continue to serve, as a director, officer, employee or agent of the
Company, as the case may be, if Indemnitee is furnished the indemnity provided for herein by the Company. 

AGREEMENT 
 NOW THEREFORE, in consideration of the mutual covenants and agreements set forth herein, the parties hereto, intending to be legally bound, hereby agree
as follows: 
 1. Definitions. 

(a) Agent. For purposes of this Agreement, the term “agent” of the Company means any person who:
(i) is or was a director, officer, employee or other fiduciary of the Company or a subsidiary of the Company; or (ii) is or was serving at the request or for the convenience of, or representing the interests of, the Company or a
subsidiary of the Company, as a director, officer, employee or other fiduciary of a foreign or domestic corporation, partnership, joint venture, trust or other enterprise. 

  
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 (b) Expenses. For purposes of this Agreement, the term
“expenses” shall be broadly construed and shall include, without limitation, all direct and indirect costs of any type or nature whatsoever (including, without limitation, all attorneys’, witness, or other professional fees and
related disbursements, and other out-of-pocket costs of whatever nature), actually and reasonably incurred by Indemnitee in connection with the investigation, defense or appeal of a proceeding or establishing or enforcing a right to indemnification
under this Agreement, the Code or otherwise, and amounts paid in settlement by or on behalf of Indemnitee, but shall not include any judgments, fines or penalties actually levied against Indemnitee for such individual’s violations of law. The
term “expenses” shall also include reasonable compensation for time spent by Indemnitee for which he is not compensated by the Company or any subsidiary or third party (i) for any period during which Indemnitee is not an agent, in the
employment of, or providing services for compensation to, the Company or any subsidiary; and (ii) if the rate of compensation and estimated time involved is approved by the directors of the Company who are not parties to any action with respect
to which expenses are incurred, for Indemnitee while an agent of, employed by, or providing services for compensation to, the Company or any subsidiary. 
 (c) Proceedings. For purposes of this Agreement, the term “proceeding” shall be broadly construed and shall include, without limitation, any threatened, pending, or completed action,
suit, arbitration, alternate dispute resolution mechanism, investigation, inquiry, administrative hearing or any other actual, threatened or completed proceeding, whether brought in the right of the Company or otherwise and whether of a civil,
criminal, administrative or investigative nature, and whether formal or informal in any case, in which Indemnitee was, is or will be involved as a party or otherwise by reason of: (i) the fact that Indemnitee is or was a director or officer of
the Company; (ii) the fact that any action taken by Indemnitee or of any action on Indemnitee’s part while acting as director, officer, employee or agent of the Company; or (iii) the fact that Indemnitee is or was serving at the
request of the Company as a director, officer, employee or agent of another corporation, partnership, joint venture, trust, employee benefit plan or other enterprise, and in any such case described above, whether or not serving in any such capacity
at the time any liability or expense is incurred for which indemnification, reimbursement, or advancement of expenses may be provided under this Agreement. 
 (d) Subsidiary. For purposes of this Agreement, the term “subsidiary” means any corporation or limited liability company of which more than 50% of the outstanding voting securities or
equity interests are owned, directly or indirectly, by the Company and one or more of its subsidiaries, and any other corporation, limited liability company, partnership, joint venture, trust, employee benefit plan or other enterprise of which
Indemnitee is or was serving at the request of the Company as a director, officer, employee, agent or fiduciary. 
 (e) Independent Counsel. For purposes of this Agreement, the term “independent counsel” means a law firm, or a partner (or, if applicable, member) of such a law firm, that is experienced
in matters of corporation law and neither presently is, nor in the past five (5) years has been, retained to represent: (i) the Company or Indemnitee in any matter material to either such party, or (ii) any other party to the
proceeding giving rise to a claim for indemnification hereunder. Notwithstanding the foregoing, the term “independent counsel” shall not include any person who, under the applicable standards of professional conduct then prevailing, would
have a conflict of interest in representing either the Company or Indemnitee in an action to determine Indemnitee’s rights under this Agreement. 

  
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 2. Agreement to Serve. Indemnitee will serve, or continue to serve,
as a director, officer, employee or agent of the Company or any subsidiary, as the case may be, faithfully and to the best of his or her ability, at the will of such corporation (or under separate agreement, if such agreement exists), in the
capacity Indemnitee currently serves as an agent of such corporation, so long as Indemnitee is duly appointed or elected and qualified in accordance with the applicable provisions of the bylaws or other applicable charter documents of such
corporation, or until such time as Indemnitee tenders his or her resignation in writing; provided, however, that nothing contained in this Agreement is intended as an employment agreement between Indemnitee and the Company or any of its subsidiaries
or to create any right to continued employment of Indemnitee with the Company or any of its subsidiaries in any capacity. 
 The Company acknowledges that it has entered into this Agreement and assumes the obligations imposed on it hereby, in addition to and separate from its obligations to Indemnitee under the Bylaws, to
induce Indemnitee to serve, or continue to serve, as a director, officer, employee or agent of the Company, and the Company acknowledges that Indemnitee is relying upon this Agreement in serving as a director, officer, employee or agent of the
Company. 
 3. Indemnification. 

(a) Indemnification in Third Party Proceedings. Subject to Section 10 below, the Company shall indemnify
Indemnitee to the fullest extent permitted by the Code, as the same may be amended from time to time (but, only to the extent that such amendment permits Indemnitee to broader indemnification rights than the Code permitted prior to adoption of such
amendment), if Indemnitee is a party to or threatened to be made a party to or otherwise involved in any proceeding, for any and all expenses, actually and reasonably incurred by Indemnitee in connection with the investigation, defense, settlement
or appeal of such proceeding. 
 (b) Indemnification in Derivative Actions and Direct Actions by the
Company. Subject to Section 10 below, the Company shall indemnify Indemnitee to the fullest extent permitted by the Code, as the same may be amended from time to time (but, only to the extent that such amendment permits Indemnitee to
broader indemnification rights than the Code permitted prior to adoption of such amendment), if Indemnitee is a party to or threatened to be made a party to or otherwise involved in any proceeding by or in the right of the Company to procure a
judgment in its favor, against any and all expenses actually and reasonably incurred by Indemnitee in connection with the investigation, defense, settlement, or appeal of such proceedings. 

4. Indemnification of Expenses of Successful Party. Notwithstanding any other provision of this Agreement, to the
extent that Indemnitee has been successful on the merits or otherwise in defense of any proceeding or in defense of any claim, issue or matter therein, including the dismissal of any action without prejudice, the Company shall indemnify Indemnitee
against all expenses actually and reasonably incurred in connection with the investigation, defense or appeal of such proceeding. 

  
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 5. Partial Indemnification. If Indemnitee is entitled under any
provision of this Agreement to indemnification by the Company for some or a portion of any expenses actually and reasonably incurred by Indemnitee in the investigation, defense, settlement or appeal of a proceeding, but is precluded by applicable
law or the specific terms of this Agreement to indemnification for the total amount thereof, the Company shall nevertheless indemnify Indemnitee for the portion thereof to which Indemnitee is entitled. 

6. Advancement of Expenses. To the extent not prohibited by law, the Company shall advance the expenses incurred
by Indemnitee in connection with any proceeding, and such advancement shall be made within twenty (20) days after the receipt by the Company of a statement or statements requesting such advances (which shall include invoices received by
Indemnitee in connection with such expenses but, in the case of invoices in connection with legal services, any references to legal work performed or to expenditures made that would cause Indemnitee to waive any privilege accorded by applicable law
shall not be included with the invoice) and upon request of the Company, an undertaking to repay the advancement of expenses if and to the extent that it is ultimately determined by a court of competent jurisdiction in a final judgment, not subject
to appeal, that Indemnitee is not entitled to be indemnified by the Company. Advances shall be unsecured, interest free and without regard to Indemnitee’s ability to repay the expenses. Advances shall include any and all expenses actually and
reasonably incurred by Indemnitee pursuing an action to enforce Indemnitee’s right to indemnification under this Agreement, or otherwise and this right of advancement, including expenses incurred preparing and forwarding statements to the
Company to support the advances claimed. Indemnitee acknowledges that the execution and delivery of this Agreement shall constitute an undertaking providing that Indemnitee shall, to the fullest extent required by law, repay the advance if and to
the extent that it is ultimately determined by a court of competent jurisdiction in a final judgment, not subject to appeal, that Indemnitee is not entitled to be indemnified by the Company. The right to advances under this Section shall continue
until final disposition of any proceeding, including any appeal therein. This Section 6 shall not apply to any claim made by Indemnitee for which indemnity is excluded pursuant to Section 10(b). 

7. Notice and Other Indemnification Procedures. 

(a) Notification of Proceeding. Indemnitee will notify the Company in writing promptly upon being served with any
summons, citation, subpoena, complaint, indictment, information or other document relating to any proceeding or matter which may be subject to indemnification or advancement of expenses covered hereunder. The failure of Indemnitee to so notify the
Company shall not relieve the Company of any obligation which it may have to Indemnitee under this Agreement or otherwise. 
 (b) Request for Indemnification and Indemnification Payments. Indemnitee shall notify the Company promptly in writing upon receiving notice of any demand, judgment or other requirement for payment
that Indemnitee reasonably believes to be subject to indemnification under the terms of this Agreement, and shall request payment thereof by the Company. Indemnification payments requested by Indemnitee under Section 3 hereof shall be made by
the Company no later than sixty (60) days after receipt of the written request of Indemnitee. Claims for advancement of expenses shall be made under the provisions of Section 6 herein. 

  
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 (c) Application for Enforcement. In the event the Company fails to
make timely payments as set forth in Sections 6 or 7(b) above, Indemnitee shall have the right to apply to any court of competent jurisdiction for the purpose of enforcing Indemnitee’s right to indemnification or advancement of expenses
pursuant to this Agreement. In such an enforcement hearing or proceeding, the burden of proof shall be on the Company to prove that indemnification or advancement of expenses to Indemnitee is not required under this Agreement or permitted by
applicable law. Any determination by the Company (including its Board of Directors, stockholders or independent counsel) that Indemnitee is not entitled to indemnification hereunder, shall not be a defense by the Company to the action nor create any
presumption that Indemnitee is not entitled to indemnification or advancement of expenses hereunder. 
 (d)
Indemnification of Certain Expenses. The Company shall indemnify Indemnitee against all expenses incurred in connection with any hearing or proceeding under this Section 7 unless the Company prevails in such hearing or proceeding on the
merits in all material respects. 
 8. Assumption of Defense. In the event the Company shall be requested
by Indemnitee to pay the expenses of any proceeding, the Company, if appropriate, shall be entitled to assume the defense of such proceeding, or to participate to the extent permissible in such proceeding, with counsel reasonably acceptable to
Indemnitee. Upon assumption of the defense by the Company and the retention of such counsel by the Company, the Company shall not be liable to Indemnitee under this Agreement for any fees of counsel subsequently incurred by Indemnitee with respect
to the same proceeding, provided that Indemnitee shall have the right to employ separate counsel in such proceeding at Indemnitee’s sole cost and expense. Notwithstanding the foregoing, if Indemnitee’s counsel delivers a written notice to
the Company stating that such counsel has reasonably concluded that there may be a conflict of interest between the Company and Indemnitee in the conduct of any such defense or the Company shall not, in fact, have employed counsel or otherwise
actively pursued the defense of such proceeding within a reasonable time, then in any such event the fees and expenses of Indemnitee’s counsel to defend such proceeding shall be subject to the indemnification and advancement of expenses
provisions of this Agreement. 
 9. Insurance. To the extent that the Company maintains an insurance
policy or policies providing liability insurance for directors, officers, employees, or agents of the Company or of any subsidiary (“D&O Insurance”), Indemnitee shall be covered by such policy or policies in accordance with its or
their terms to the maximum extent of the coverage available for any such director, officer, employee or agent under such policy or policies. If, at the time of the receipt of a notice of a claim pursuant to the terms hereof, the Company has D&O
Insurance in effect, the Company shall give prompt notice of the commencement of such proceeding to the insurers in accordance with the procedures set forth in the respective policies. The Company shall thereafter take all necessary or desirable
action to cause such insurers to pay, on behalf of Indemnitee, all amounts payable as a result of such proceeding in accordance with the terms of such policies. 

  
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 10. Exceptions. 

(a) Certain Matters. Any provision herein to the contrary notwithstanding, the Company shall not be obligated
pursuant to the terms of this Agreement to indemnify Indemnitee on account of any proceeding with respect to (i) remuneration paid to Indemnitee if it is determined by final judgment or other final adjudication that such remuneration was in
violation of law (and, in this respect, both the Company and Indemnitee have been advised that the Securities and Exchange Commission believes that indemnification for liabilities arising under the federal securities laws is against public policy
and is, therefore, unenforceable and that claims for indemnification should be submitted to appropriate courts for adjudication, as indicated in Section 10(d) below); (ii) a final judgment rendered against Indemnitee for an accounting,
disgorgement or repayment of profits made from the purchase or sale by Indemnitee of securities of the Company against Indemnitee or in connection with a settlement by or on behalf of Indemnitee to the extent it is acknowledged by Indemnitee and the
Company that such amount paid in settlement resulted from Indemnitee’s conduct from which Indemnitee received monetary personal profit, pursuant to the provisions of Section 16(b) of the Securities Exchange Act of 1934, as amended, or
other provisions of any federal, state or local statute or rules and regulations thereunder; (iii) a final judgment or other final adjudication that Indemnitee’s conduct was in bad faith, knowingly fraudulent or deliberately dishonest or
constituted willful misconduct (but only to the extent of such specific determination); or (iv) on account of conduct that is established by a final judgment as constituting a breach of Indemnitee’s duty of loyalty to the Company or
resulting in any personal profit or advantage to which Indemnitee is not legally entitled. For purposes of the foregoing sentence, a final judgment or other adjudication may be reached in either the underlying proceeding or action in connection with
which indemnification is sought or a separate proceeding or action to establish rights and liabilities under this Agreement. 
 (b) Claims Initiated by Indemnitee. Any provision herein to the contrary notwithstanding, the Company shall not be obligated to indemnify or advance expenses to Indemnitee with respect to
proceedings or claims initiated or brought by Indemnitee against the Company or its directors, officers, employees or other agents and not by way of defense, except (i) with respect to proceedings brought to establish or enforce a right to
indemnification under this Agreement or under any other agreement, provision in the Bylaws or Certificate of Incorporation or applicable law, or (ii) with respect to any other proceeding initiated by Indemnitee that is either approved by the
Board of Directors or Indemnitee’s participation is required by applicable law. However, indemnification or advancement of expenses may be provided by the Company in specific cases if the Board of Directors determines it to be appropriate.

 (c) Unauthorized Settlements. Any provision herein to the contrary notwithstanding, the Company shall
not be obligated pursuant to the terms of this Agreement to indemnify Indemnitee under this Agreement for any amounts paid in settlement of a proceeding effected without the Company’s written consent. Neither the Company nor Indemnitee shall
unreasonably withhold consent to any proposed settlement; provided, however, that the Company may in any event decline to consent to (or to otherwise admit or agree to any liability for indemnification hereunder in respect of) any proposed
settlement if the Company is also a party in such proceeding and determines in good faith that such settlement is not in the best interests of the Company and its stockholders. 

  
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 (d) Securities Act Liabilities. Any provision herein to the contrary
notwithstanding, the Company shall not be obligated pursuant to the terms of this Agreement to indemnify Indemnitee or otherwise act in violation of any undertaking appearing in and required by the rules and regulations promulgated under the
Securities Act of 1933, as amended (the “Act”), or in any registration statement filed with the SEC under the Act. Indemnitee acknowledges that paragraph (h) of Item 512 of Regulation S-K currently generally requires the Company
to undertake in connection with any registration statement filed under the Act to submit the issue of the enforceability of Indemnitee’s rights under this Agreement in connection with any liability under the Act on public policy grounds to a
court of appropriate jurisdiction and to be governed by any final adjudication of such issue. Indemnitee specifically agrees that any such undertaking shall supersede the provisions of this Agreement and to be bound by any such undertaking.

 11. Nonexclusivity and Survival of Rights. The provisions for indemnification and advancement of
expenses set forth in this Agreement shall not be deemed exclusive of any other rights which Indemnitee may at any time be entitled under any provision of applicable law, the Company’s Certificate of Incorporation, Bylaws or other agreements,
both as to action in Indemnitee’s official capacity and Indemnitee’s action as an agent of the Company, in any court in which a proceeding is brought, and Indemnitee’s rights hereunder shall continue after Indemnitee has ceased acting
as an agent of the Company and shall inure to the benefit of the heirs, executors, administrators and assigns of Indemnitee. The obligations and duties of the Company to Indemnitee under this Agreement shall be binding on the Company and its
successors and assigns until terminated in accordance with its terms. The Company shall require any successor (whether direct or indirect, by purchase, merger, consolidation or otherwise) to all or substantially all of the business or assets of the
Company, expressly to assume and agree to perform this Agreement in the same manner and to the same extent that the Company would be required to perform if no such succession had taken place. 

No amendment, alteration or repeal of this Agreement or of any provision hereof shall limit or restrict any right of
Indemnitee under this Agreement in respect of any action taken or omitted by such Indemnitee in his or her corporate status prior to such amendment, alteration or repeal. To the extent that a change in the Code, whether by statute or judicial
decision, permits greater indemnification or advancement of expenses than would be afforded currently under the Company’s Certificate of Incorporation, Bylaws and this Agreement, it is the intent of the parties hereto that Indemnitee shall
enjoy by this Agreement the greater benefits so afforded by such change. No right or remedy herein conferred is intended to be exclusive of any other right or remedy, and every other right and remedy shall be cumulative and in addition to every
other right and remedy given hereunder or now or hereafter existing at law or in equity or otherwise. The assertion or employment of any right or remedy hereunder, or otherwise, by Indemnitee shall not prevent the concurrent assertion or employment
of any other right or remedy by Indemnitee. 
 12. Term. This Agreement shall continue until and
terminate upon the later of: (a) five (5) years after the date that Indemnitee shall have ceased to serve as a director or and/or officer, employee or agent of the Company; or (b) one (1) year after the final termination of any
proceeding, including any appeal then pending, in respect to which Indemnitee was granted rights of indemnification or advancement of expenses hereunder. 

  
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 No legal action shall be brought and no cause of action shall be asserted by
or in the right of the Company against an Indemnitee or an Indemnitee’s estate, spouse, heirs, executors or personal or legal representatives after the expiration of five (5) years from the date of accrual of such cause of action, and any
claim or cause of action of the Company shall be extinguished and deemed released unless asserted by the timely filing of a legal action within such five-year period; provided, however, that if any shorter period of limitations is otherwise
applicable to such cause of action, such shorter period shall govern. 
 13. Subrogation. In the event of
payment under this Agreement, the Company shall be subrogated to the extent of such payment to all of the rights of recovery of Indemnitee, who, at the request and expense of the Company, shall execute all papers required and shall do everything
that may be reasonably necessary to secure such rights, including the execution of such documents necessary to enable the Company effectively to bring suit to enforce such rights. 

14. Interpretation of Agreement. It is understood that the parties hereto intend this Agreement to be interpreted
and enforced so as to provide indemnification to Indemnitee to the fullest extent now or hereafter permitted by law. 
 15. Severability. If any provision of this Agreement shall be held to be invalid, illegal or unenforceable for any reason whatsoever, (a) the validity, legality and enforceability of the
remaining provisions of the Agreement (including without limitation, all portions of any paragraphs of this Agreement containing any such provision held to be invalid, illegal or unenforceable, that are not themselves invalid, illegal or
unenforceable) shall not in any way be affected or impaired thereby; and (b) to the fullest extent possible, the provisions of this Agreement (including, without limitation, all portions of any paragraph of this Agreement containing any such
provision held to be invalid, illegal or unenforceable, that are not themselves invalid, illegal or unenforceable) shall be construed so as to give effect to the intent manifested by the provision held invalid, illegal or unenforceable and to give
effect to Section 14 hereof. 
 16. Amendment and Waiver. No supplement, modification, amendment, or
cancellation of this Agreement shall be binding unless executed in writing by the parties hereto. No waiver of any of the provisions of this Agreement shall be deemed or shall constitute a waiver of any other provision hereof (whether or not
similar) nor shall such waiver constitute a continuing waiver. 
 17. Notice. Except as otherwise
provided herein, any notice or demand which, by the provisions hereof, is required or which may be given to or served upon the parties hereto shall be in writing and, if by telegram, telecopy or telex, shall be deemed to have been validly served,
given or delivered when sent, if by overnight delivery, courier or personal delivery, shall be deemed to have been validly served, given or delivered upon actual delivery and, if mailed, shall be deemed to have been validly served, given or
delivered three (3) business days after deposit in the United States mail, as registered or certified mail, with proper postage prepaid and addressed to the party or parties to be notified at the addresses set forth on the signature page of
this Agreement (or such other address(es) as a party may designate for itself by like notice). If to the Company, notices and demands shall be delivered to the attention of the Secretary of the Company. 

  
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 18. Governing Law. This Agreement shall be governed exclusively by
and construed according to the laws of the State of Delaware, as applied to contracts between Delaware residents entered into and to be performed entirely within Delaware. 

19. Counterparts. This Agreement may be executed in one or more counterparts, each of which shall for all purposes
be deemed to be an original but all of which together shall constitute but one and the same Agreement. Only one such counterpart need be produced to evidence the existence of this Agreement. 

20. Headings. The headings of the sections of this Agreement are inserted for convenience only and shall not be
deemed to constitute part of this Agreement or to affect the construction hereof. 
 21. Entire
Agreement. This Agreement constitutes the entire agreement between the parties with respect to the subject matter hereof and supersedes all prior agreements, understandings and negotiations, written and oral, between the parties with respect to
the subject matter of this Agreement; provided, however, that this Agreement is a supplement to and in furtherance of the Company’s Certificate of Incorporation, Bylaws, the Code and any other applicable law, and shall not be deemed a
substitute therefor, and does not diminish or abrogate any rights of Indemnitee thereunder. 

  
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 IN WITNESS
WHEREOF, the parties hereto have entered into this Agreement effective as of the date first above written. 
  

			
	 COMPANY
  

WORLD HEART CORPORATION

		
	 By:    
	 	 
		 	
Name:                            
                                    

		 	
Title:                            
                                    

	  
 INDEMNITEE

	
	 
	 Signature of Indemnitee

	
	 
	 Print or Type Name of IndemniteeAsset Purchase Agreement dated July 11, 2011

 EXHIBIT 10.24 

 
  

 
 ASSET PURCHASE AGREEMENT

 dated as of July 11, 2011 
 by and between 
 WORLD HEART CORPORATION 

(“Seller”) 
 and 
 SYNCARDIA SYSTEMS, INC. 

(“Buyer”) 
  

 
  

 ASSET PURCHASE AGREEMENT 

THIS ASSET PURCHASE AGREEMENT, dated as of July 11, 2011 (the “Effective Date”) is entered into by
and between WORLD HEART CORPORATION, a Delaware corporation (“Seller”), and SYNCARDIA SYSTEMS, INC., a Delaware corporation (“Buyer”). 

WHEREAS, Seller wishes to sell to Buyer the Purchased Assets (as defined below), and Buyer wishes to purchase such assets
from Seller. 
 NOW, THEREFORE, in consideration of the premises and mutual covenants, agreements and provisions
herein contained, the parties hereto agree as follows: 
 ARTICLE 1 

Definitions 
 1.1 Definitions. 
 The following terms have the following
meanings when used herein: 
 “Affiliate” shall mean a Person that directly, or indirectly
through one or more intermediaries, controls or is controlled by, or is under common control with, the Person specified. For purposes of this definition, the terms “control,” “controlled by” and “under common control
with” shall mean the possession, directly or indirectly, of the power to direct or cause the direction of the management or policies of such Person and, in the case of an entity, shall require (i) in the case of a corporate entity, direct
or indirect ownership of at least a majority of the securities having the right to vote for the election of directors, and (ii) in the case of a non-corporate entity, direct or indirect ownership of at least a majority of the equity interests
with the power to direct the management and policies of such non-corporate entity. 

“Agreement” means this Asset Purchase Agreement, including all Schedules and Exhibits hereto, as it may
be amended from time to time in accordance with its terms. 
 “Assignment and Assumption
Agreement” means the Assignment and Assumption Agreement and Bill of Sale in substantially the form attached hereto as Exhibit A. 
 “Assumed Liability” or “Assumed Liabilities” has the meaning set forth in Section 2.2. 

“Buyer” has the meaning set forth in the preamble hereto. 

“Closing” means the closing of the purchase and sale of the Purchased Assets contemplated by this
Agreement. 

 “Commercially Reasonable Diligent Efforts” means the
commercially reasonable diligent exercise, dedication and expenditure of efforts, money, personnel, and resources as reasonably needed to complete each of the events triggering the additional payments to Seller set forth in Sections 3.1(b),
(c) and (d). Such efforts shall be documented and must be consistent with those utilized by companies of similar size and type. 
 “Confidential Information” has the meaning set forth in Section 10.3. 
 “Effective Date” means the date set forth in preamble. 
 “Escrow Agreement” means that certain Escrow Agreement between Seller, Buyer and JPMorgan Chase Bank, National Association as Escrow Agent dated on or about the Effective Date in
substantially the form attached hereto as Exhibit B. 
 “Escrow Agent” means JPMorgan
Chase Bank, National Association. 
 “Ethicon/Baxter Agreement” means that certain agreement by
and between Ethicon, Inc. and Baxter Healthcare Corporation, dated as of March 10, 1994, and as subsequently amended by letter dated March 11, 1994. 
 “Excluded Liability” has the meaning set forth in Section 2.3. 
 “FDA” means the United States Food and Drug Administration and any successor agency thereto. 
 “Nontransferred Assets” has the meaning set forth in Section 4.2(c). 
 “Other Agreements” means, collectively, the Assignment and Assumption Agreement and the Escrow Agreement. 

“Person” means any individual, corporation, partnership, limited partnership, joint venture, limited
liability company, trust or unincorporated organization, governmental entity, government or any agency or political subdivision thereof. 
 “Pre-Closing Services and Expenses” has the meaning set forth in Section 7.2. 
 “Purchase Price” has the meaning set forth in Section 3.1. 
 “Purchased Assets” has the meaning set forth in Section 2.1. 
 “Raw Materials” means those raw materials set forth on Schedule 2.1(e). 
 “Reactor” means the five gallon stainless steel reactor with heating jacket and variable speed double helix spiral agitator used in the synthesis of SPUS. 

“Seller” has the meaning set forth in the preamble hereto. 

  
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 “Segmented Polyurethane” or “SPU” means a
reaction product made from polytetramethylene oxide glycol and methylene-bis (4-phenylisocyanate) which is then further reacted with a mixture of chain extenders ethylene diamine, 1,3-diaminocyclohexane, diethylamine, “Santowhite” powder,
and a copolymer of diisopropylamino ethyl methacrylate with n-decyl methacrylate. 
 “Segmented
Polyurethane Solution” or “SPUS” means a solution of Segmented Polyurethane in dimethylacetamide (DMAC). 
 “SPUS Lots” has the meaning set forth in Section 2.1(d). 
 ‘Technical Information” has the meaning set forth in Section 2.1(b). . 
 ARTICLE 2 
 Purchase and Sale 

2.1 Purchased Assets. 
 Subject to the terms and conditions contained herein, at the Closing, Seller shall sell, transfer, convey, assign and deliver to Buyer, and Buyer shall purchase and acquire from Seller, all right, title,
and interest of Seller in and to all assets owned or controlled by Seller that are necessary for the synthesis of SPU and SPUS which include the following (collectively, the “Purchased Assets”): 

(a) all documents, correspondence, studies, reports, and all other records of every kind, tangible data,
data and laboratory books, media records, research material, blueprints, technology, technical designs, drawings, specifications and other product development records of the Seller, relating to the Purchased Assets; 

(b) written documentation and specifications owned and controlled by Seller which pertain to the Purchased
Assets, Raw Materials and the manufacture, synthesis, quality control, testing, maintenance, storage and handling of SPU, SPUS and Raw Materials, including all references and standards, methodologies, processes, protocols, specifications,
techniques, trade secrets and know how, databases and formulas related to the Purchased Assets and any supporting documentation, (collectively, the “Technical Information”)”); 

(c) all rights and interest of Seller under and to the Ethicon/Baxter Agreement; 

(d) three (3) lots of previously manufactured SPUS as more particularly described in Schedule
2.1(d) (the “SPUS Lots”); 
 (e) the Raw Materials specified on Schedule
2.1(e); 
 (f) the Reactor. 

  
 3 

 2.2 Assumed Liabilities. On the Effective Date, Buyer shall assume
the following “Assumed Liabilities”: 
 (a) all liabilities and all obligations
arising after the Effective Date under the Ethicon/Baxter Agreement; 
 (b) all liabilities or
other claims arising from the use of the Purchased Assets, the use of the SPUS Lots and from the use of the Raw Materials by Buyer after the closing. 
 2.3 Excluded Liabilities. 
 Buyer does not assume nor will
it become responsible for any of the liabilities and obligations of Seller under the Purchased Assets (collectively, the “Excluded Liabilities”) (i) that arose on or before the Effective Date, (ii) arise from or relate to
any breach by the Seller of any provision of this Agreement or any Other Agreement on or before the Effective Date, (iii) arise from or relate to any event, circumstance or condition occurring or existing on or before the Effective Date that
with notice or lapse of time, would constitute or result in a breach of any of such Agreement or Other Agreement and (iv) arise from the failure to obtain any required consent from any third party, if any, in connection with the assignment and
transfer of such Agreement or Other Agreement to the Buyer pursuant to this Agreement. 
 ARTICLE 3 

Purchase Price 
 3.1 Purchase Price.  
 Subject to the terms and
conditions hereof, Buyer shall pay to Seller, a total purchase price of Eight-Hundred Thousand Dollars ($800,000.00) (the “Purchase Price”) for the Purchased Assets payable as follows: 

(a) One-Hundred Thousand Dollars ($100,000.00), non-refundable and due and payable on the Effective Date;

 (b) One-Hundred and Fifty Thousand Dollars ($150,000.00) non-refundable and due and payable
within one (1) business day of completion of installation of the Reactor at Buyer’s premises located at 1992 E. Silverlake, Tucson, AZ 85713. Installation will be deemed completed when the Installation Qualification Protocol has been
executed and a final report is signed off. 
 (c) Two-Hundred and Fifty Thousand Dollars
($250,000.00) shall be delivered to the Escrow Agent for deposit into an escrow account within one (1) business day of Buyer’s production of the first batch of non-clinical grade SPUS, to be released to Seller only upon achievement of the
payment event specified in Section 3.1(d) below in accordance with the terms of the Escrow Agreement as noted by completion and final report of the Operational Qualification (OQ); 

  
 4 

 (d) Three-Hundred Thousand Dollars ($300,000.00) due and
payable within one (1) business day of production of the first batch of clinical grade SPUS by Buyer as noted by the completion and final report of the process qualification (PQ). 

3.2 Payment of Purchase Price. 

The portions of the Purchase Price described in Sections 3.1(a), (b) and (d) shall be paid by wire
transfer of immediately available funds to the account previously designated in writing by Seller to Buyer in accordance with this Section 3. The portion of the Purchase Price described in Section 3.1(c) shall be paid in
accordance with the Escrow Agreement. 
 ARTICLE 4 
 Closing 
 4.1 Closing. 

The Closing shall take place on the Effective Date at a place and location to be agreed upon between Buyer and Seller.

 4.2 Transactions at Closing.  

At the Closing, subject to the terms and conditions hereof: 

(a) Transfer of Purchased Assets. Seller shall transfer and convey or cause to be transferred and
conveyed to Buyer all of the Purchased Assets and Seller and Buyer shall execute and deliver this Agreement and each of the Other Agreements and Seller shall deliver to Buyer such other good and sufficient instruments of transfer and conveyance as
shall be necessary to vest in Buyer title to all of the Purchased Assets or as shall be reasonably requested by the Buyer. 
 (b) Payment of Purchase Price, Pre-Closing Services Costs and Escrow Fee. In addition to the portion of the Purchase Price due and payable in accordance with Section 3.1(a) at the
Closing, Buyer shall, on the Effective Date: (i) pay to Seller $ 5,750.00 for the Pre-Closing services provided by Seller personnel as required by Section 7.2 below, and (ii) $1,250.00, which is equal to one-half of the fee
charged by the Escrow Agent for services rendered by it under the Escrow Agreement. Such payments shall be made by electronic bank transfer in immediately available funds directly to Seller’s Account for which wiring instructions shall be
provided to Buyer by Seller in writing before the Closing. 

  
 5 

 (c) Post-Closing Transfers. Following the Closing, the
parties shall cooperate with each other to identify any assets that were not transferred as part of the Purchased Assets at the Closing but that, pursuant to the provisions of this Agreement, were required to be transferred (the
“Nontransferred Assets”). To the extent any Nontransferred Assets are identified and Seller is legally and contractually permitted to transfer such assets, Seller shall, at no cost to Buyer other than Buyer’s responsibility to
pay for all shipping costs, promptly take all actions to transfer such Nontransferred Assets to Buyer. In the event Seller is required to obtain the consent or approval of any Person prior to the transfer of any Nontransferred Asset, then Seller
shall, at its own expense, use its commercially reasonable efforts to promptly obtain such approval or consent, and upon obtaining such approval or consent, shall promptly transfer such Nontransferred Asset to Buyer at no cost to Buyer other than
Buyer’s responsibility to pay for all shipping costs. In the event the Seller is unable to obtain such approval or consent, then Seller and Buyer shall discuss in good faith an appropriate resolution for the transfer of the economic benefit of
such Nontransferred Asset to Buyer. 
 ARTICLE 5 
 Representations and Warranties of Seller 
 Seller
represents and warrants to Buyer as follows: 
 5.1 Organization. 

Seller is a corporation duly incorporated and validly existing in good standing under the laws of the State of Delaware
and has all requisite corporate power and authority to operate its business and to own, lease, operate and transfer the Purchased Assets. 
 5.2 Due Authorization. 
 Seller has full corporate power
and authority to execute, deliver and perform its obligations under this Agreement and the Other Agreements, and the execution and delivery of this Agreement and the Other Agreements and the performance of all of its obligations hereunder and
thereunder has been duly and validly authorized and approved by all necessary corporate action of the Seller, including approval of this Agreement and the Other Agreements by the board of directors of the Seller. The signing, delivery and
performance of this Agreement and the Other Agreements by Seller is not prohibited or limited by, and will not result in the breach of or a default under, or conflict with any obligation of Seller with respect to the Purchased Assets under
(i) any provision of the Certificate of Incorporation or By-Laws of Seller, (ii) any material agreement or instrument to which Seller is a party or by which it or its properties are bound, (iii) any judgment, order, award, writ,
injunction or decree of any court, governmental body or instrumentality, or arbitrator, (iv) any Governmental Authorizations, or (v) any applicable law, statute, ordinance, regulation or rule, and, to Seller’s knowledge, will not
result in the creation or imposition of any Encumbrance on any of the Purchased Assets, except to the extent that any such prohibition, limitation, breach, default or conflict would not reasonably be 

  
 6 

 expected to have a material adverse effect on the Purchased Assets. This Agreement and the
Other Agreements have been duly executed and delivered by Seller and constitute legal, valid and binding obligations of Seller, enforceable against Seller in accordance with their respective terms, except as enforceability may be limited or affected
by applicable bankruptcy, insolvency, moratorium, reorganization or other laws of general application relating to or affecting creditors’ rights generally. 

5.3 Title to Assets. 

(a) Seller hereby represents and warrants to Buyer that, as of the Effective Date: 

(i) Seller is the legally and beneficially sole owner of the Purchased Assets, free and clear of any
third party rights and 
 (ii) the Purchased Assets represent all intellectual property which
Seller, directly or indirectly, controls which directly relate to SPU and SPUS. 
 (b) Without
limiting the generality of the foregoing, and except for such rights as may have been retained by Ethicon, Inc. under the Ethicon/Baxter Agreement, Seller represents and warrants that, as of the Effective Date: 

(i) it is fully entitled to sell and assign all the right, title and interest in and to the Purchased
Assets; 
 (ii) it has not granted, any third party any license, or option to obtain a license,
or any other right under the Purchased Assets; and 
 (iii) its execution, delivery and
performance of this Agreement or the Other Agreements does not conflict with any obligation, agreement, instrument or understanding, oral or written, to which it is a party or by which it is bound. 

5.4 Contracts.  
 Except for the Ethicon/Baxter Agreement, there are no contracts pursuant to which Seller enjoys any right or benefit or undertakes any obligation related to the Purchased Assets, further, prior to giving
effect to the Closing, Seller has delivered to Buyer an accurate and complete copy of the Ethicon/Baxter Agreement, including any and all amendments thereto. 
 5.5 Litigation. 
 There is no litigation, proceeding, claim
or governmental investigation pending or, to Seller’s knowledge, threatened with respect to the Purchased Assets. 

  
 7 

 5.6 Brokers, Etc. 

No broker or investment banker acting on behalf of Seller or under the authority of Seller is or will be entitled to any
broker’s or finder’s fee or any other commission or similar fee directly or indirectly from Seller or Buyer in connection with any of the transactions contemplated herein, other than any fee that is the sole responsibility of Seller.

 5.7 Disclaimer. 

(a) SELLER HEREBY DISCLAIMS ANY ALL WARRANTIES, EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION
(i) ANY WARRANTY THAT BUYER WILL OBTAIN ANY PROPRIETARY RIGHTS IN OR TO ANY OF THE TECHNICAL INFORMATION, (ii) THE WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE, RELATING TO THE TECHNICAL INFORMATION, THE REACTOR, THE
SPUS LOTS, THE RAW MATERIALS OR ANY PRODUCT OR PROCESS WHICH INCORPORATES, USES OR IN ANY WAY INVOLVES SPU OR SPUS, (iii) THE SUFFICIENCY OR COMPLETENESS OF THE TECHNICAL INFORMATION, OR (iv) ANY OTHER RIGHT CLAIMED OR DERIVED BY BUYER IN
THIS AGREEMENT. 
 EXCEPT AS OTHERWISE EXPRESSLY PROVIDED IN THIS ARTICLE 5, SELLER IS MAKING NO
REPRESENTATION OR WARRANTY AS TO THE CONDITION OF THE PURCHASED ASSETS. ALL OF THE PURCHASED ASSETS ARE PURCHASED ON A “WHERE IS/AS IS” BASIS. 

SPECIFICALLY, SELLER MAKES NO REPRESENTATION OR WARRANTY WITH RESPECT TO THE MANUFACTURE, USE OR SAFETY OF
THE SPUS LOTS OR THAT SUCH SPUS LOTS WILL BE SUITABLE FOR ANY OF THE INTENDED USES OF SUCH LOTS BY BUYER. 
 SELLER MAKES NO REPRESENTATION OR WARRANTY WITH RESPECT TO THE RAW MATERIALS AND FURTHER ADVISES BUYER THAT THE RAW MATERIALS ARE, AS OF THE DATE OF THIS AGREEMENT, OUTSIDE OF THEIR SPECIFICATIONS AND
THAT SUCH RAW MATERIALS MAY NOT BE SUITABLE OR SAFE FOR ANY OF THE INTENDED USES OF SUCH MATERIALS BY BUYER. 
 (b) Seller further expressly disclaims all of the following: 
 (i) That SPU or SPUS are appropriate for any intended use of such products by Buyer. 
 (ii) That the Technical Information will enable Buyer to establish for the FDA equivalence of Buyer’s product with SPU or SPUS made by Seller. 

  
 8 

 (iii) That Buyer, or anyone who may receive the Technical
Information from or through Buyer, will be able to use the Technical Information without the assertion from any individual, company or party, of prior or superior rights, which may prevent use of the Technical Information by Buyer or anyone else, or
which may subject Buyer or any other party to actions in law or equity of whatever kind, or claims for damages of any kind or amount. 
 (iv) That the Technical Information will be of any scientific or commercial value to Buyer. 
 ARTICLE 6 
 Representations and Warranties of Buyer 

Buyer represents and warrants to Seller as follows: 

6.1 Organization. 
 Buyer is a corporation duly incorporated and validly existing in good standing under the laws of Delaware with all requisite corporate power and authority to own, lease and operate its properties and to
carry on its business as now being conducted. 
 6.2 Due Authorization. 

Buyer has full corporate power and authority to execute, deliver and perform its obligations under this Agreement and the
Other Agreements and the execution and delivery of this Agreement and the Other Agreements and the performance of all of its obligations hereunder and thereunder has been duly and validly authorized and approved by all necessary corporate action of
the Buyer, including approval of this Agreement and the Other Agreements by the board of directors of the Buyer. The signing, delivery and performance of this Agreement and the Other Agreements by Buyer is not prohibited or limited by, and will not
result in the breach of or a default under, any provision of the Certificate of Incorporation or By-Laws of Buyer or of any order, writ, injunction or decree of any court or governmental instrumentality. This Agreement and the Other Agreements have
been duly executed and delivered by Buyer and constitute legal, valid and binding obligations of Buyer, enforceable against Buyer in accordance with their respective terms, except as enforceability may be limited or affected by applicable
bankruptcy, insolvency, moratorium, reorganization or other laws of general application relating to or affecting creditors’ rights generally. 
 6.3 Litigation. 
 There is no litigation, proceeding, claim
or governmental investigation pending or, to Buyer’s knowledge, threatened relating to or affecting Buyer’s ability to purchase the Purchased Assets. 

  
 9 

 6.4 Brokers, Etc. 

Except for fees and expenses which shall be the sole responsibility of Buyer, no broker or investment banker acting on
behalf of Buyer is or will be entitled to any broker’s or finder’s fee or any other commission or similar fee directly or indirectly in connection with any of the transactions contemplated hereby. 

6.5 Independent Investigation. 

In making the decision to enter into this Agreement and the Other Agreements and to consummate the transactions
contemplated hereby and thereby, the Buyer has only relied on its own independent investigation, analysis and evaluation of the Purchased Assets. 
 ARTICLE 7 
 Post-Closing Covenants, Other Agreements 

7.1 Post-Closing Delivery. 

Buyer and Seller acknowledge that title and risk of loss with respect to all Purchased Assets shall pass to Buyer at
Closing. Buyer agrees to arrange for physical delivery of all tangible Purchased Assets to Buyer at Buyer’s sole cost and expense. To the extent that any Purchased Assets are not delivered at the Closing, Seller agrees to use commercially
reasonable efforts to preserve and maintain the tangible Purchased Assets in good working condition and to protect such Purchased Assets against spoilage, deterioration and other wasting. 

7.2 Transition Services and Expenses. 

Prior to the Effective Date, Seller and its employees have been engaged in activities, including the purchase of
materials that will aid in the orderly transfer of the Purchased Assets and will enhance Buyer’s ability to effectively utilize the Purchased Assets that Buyer has acquired from Seller. To this effect Buyer has agreed to reimburse Seller $
5,750.00 for the time expended by Seller’s employees, expenses incurred for the acquisition of materials and out-of-pocket costs incurred by Seller in these efforts with said amount being due and payable at Closing (the “Pre-Closing
Services and Expenses”). Following the Closing, to assist Buyer in the orderly transfer of the Purchased Assets and the accomplishment of the diligence requirements set forth in Section 7.3 below, Buyer and Seller shall use
commercially reasonable efforts to allow and cause Buyer to enter into agreements with former or current Seller personnel, including but not limited to Lori Berring, an employee and senior chemist for Seller, to assist in the transfer of the
Technical Information and the installation of the equipment included within the Purchased Assets and the validation of the SPUS manufacturing process at Buyer. Any such agreements shall be entered into solely between Buyer and such personnel and
Seller shall not be a party to the agreements. For a period of not more than four (4) months from the Effective Date, Seller shall accommodate such reasonable requests as necessary and permit such personnel to take un-paid leaves of absence or
personal time to perform services requested by Buyer. 

  
 10 

 7.3 Buyer Diligence Obligations. 

Upon execution of this Agreement, Buyer shall proceed with Commercially Reasonable Diligent Efforts to complete each of
the events triggering the additional payments to Seller set forth in Sections 3.1(b), (c) and (d) above. To that effect, Buyer shall accomplish the following obligations as part of its diligence obligations hereunder: 

(a) Buyer shall complete the installation of the Reactor at Buyer’s premises within forty-five
(45) days of the Effective Date. 
 (b) Buyer shall produce the first batch of non-clinical
grade SPUS within seventy-five (75) days of the Effective Date. 
 (c) Buyer shall produce
the first batch of clinical grade SPUS within one hundred and five (105) days of the Effective Date. 
 If Buyer fails to
meet any of the foregoing diligence obligations, then, except to the extent such failure is not caused by Seller’s delay, action or inaction, upon the payment of the applicable extension fee set forth below Seller will grant to Buyer, upon
Buyer’s request, a one-time thirty (30) day extension of time to meet Buyer’s missed diligence commitment. The first request for a thirty (30) day extension of time to meet Buyer’s diligence commitments shall require the
payment of Twenty-Five Thousand Dollars ($25,000.00) by Buyer to Seller. The second request for a thirty (30) day extension of time to meet Buyer’s diligence commitments shall require the payment of Fifty Thousand Dollars ($50,000.00) by
Buyer to Seller. The third request for a thirty (30) day extension of time to meet Buyer’s diligence commitment shall require the payment of Seventy-Five Thousand Dollars ($75,000.00) by Buyer to Seller. Each subsequent extension request
will require the payment of an additional One Hundred Thousand Dollars ($100,000.00). If, at the end of any extension, Buyer has not achieved such diligence event, then Seller may exercise its rights to terminate this Agreement, require the return
of Purchased Assets and retain monies paid to Buyer by Seller through the date of termination in accordance with Article 9 below. For clarification, if Buyer makes payment to extend the time to meet a diligence commitment described in
Section 7.3(a) or (b) for thirty (30) days as described above, thereafter the time in which Buyer is required to meet all subsequent diligence commitments shall automatically be extended by thirty (30) days without additional
payment. For example, if Buyer is unable to install the Reactor within forty-five (45) days of the Effective Date and makes the first Twenty-Five Thousand Dollar ($25,000) payment to extend the time to complete the installation of the Reactor
to seventy-five (75) days from the Effective Date, automatically and without additional payment, the time in which Buyer must produce the first batch of non-clinical grade SPUS shall thereafter be one hundred five (105) days from the
Effective Date and the time in which Buyer must produce the first batch of clinical grade SPUS shall be one hundred thirty five (135) days from the Effective Date. If, after the grant of the first thirty (30) day extension Buyer is not
able to meet any of the revised diligence achievement dates and desires to extend such date by another thirty (30) days, the second extension fee shall be Fifty Thousand Dollars ($50,000.00), and the third extension fee shall be Seventy-five
Thousand Dollars ($75,000.00). Seller has no obligation to grant Buyer more than one (1) extension per diligence obligation set forth above. 

  
 11 

 ARTICLE 8 
 Indemnification and Survival 
 8.1 Indemnification

 (a) By Seller. Seller agrees to indemnify and hold harmless Buyer and its respective
stockholders, directors, officers, employees and representatives from any and all loss, liability, claim, damage, expense or financial responsibility of whatever kind, direct or consequential, compensating or punitive, including without limitation
reasonable attorneys and other legal fees and expenses, which result from, or are in any way based on or related to, directly or indirectly, this Agreement or any activity contemplated hereby including: (i) any breach of any of the
representations, warranties, covenants and agreements of Seller set forth in this Agreement or the Other Agreements; (ii) any Excluded Liability; or (iii) the ownership and use of the Purchased Assets on or before the Effective Date.

 (b) By Buyer. Buyer agrees to indemnify and hold harmless Seller and its respective
stockholders, directors, officers, employees and representatives from any and all loss, liability, claim, damage, expense or financial responsibility of whatever kind, direct or consequential, compensating or punitive, including without limitation
reasonable attorneys and other legal fees and expenses, which result from, or are in any way based on or related to, directly or indirectly, this Agreement or any activity contemplated hereby including: (i) any breach of any of the
representations, warranties, covenants and agreements of Buyer set forth in this Agreement or the Other Agreements; (ii) any Assumed Liability; or (iii) the ownership and use of the Purchased Assets after the Effective Date. 

8.2 Notice of Claim. 
 The party seeking indemnification (“Indemnified Party”) shall notify the other party (“Indemnifying Party”) of any claims which may be the subject of indemnity under this
Agreement. Failure to provide such notice timely shall only excuse Indemnifying Party from providing indemnity if Indemnifying Party did not otherwise have knowledge of such claim and if Indemnifying Party’s position was in fact materially
prejudiced by the failure to receive such notice. Indemnifying Party may at its option and its expense assume the defense and control of any claim or lawsuit brought against Indemnified Party and subject to this indemnity, using counsel selected by
Indemnifying Party with the consent of Indemnified Party, which shall not be unreasonably withheld. Indemnified Party has the right to select counsel satisfactory to it to represent its interest in the claim against Indemnified Party covered by
Indemnifying Party’s indemnity at Indemnified Party’s own expense. In any event, neither party will enter any settlement which may be the subject of indemnity without the consent of the other, which consent shall not be unreasonably
withheld. 

  
 12 

 ARTICLE 9 
 Termination 
 9.1 Termination of Agreement.

 This Agreement may be terminated immediately by Seller in the event Buyer fails to achieve, within the agreed
upon time periods (including any extensions thereof), any of the diligence requirements set forth in Section 7.3(a), (b) or (c). Upon receipt of written notice from Seller of Seller’s exercise of its right to terminate this
Agreement, Buyer shall, within fifteen (15) days of receipt of Seller’s notice of termination of the Agreement, at its own cost, return to Seller all Purchased Assets delivered to Buyer by Seller, including the Reactor and Technical
Information. All amounts of the Purchase Price paid to Seller by Buyer prior to the exercise of Seller’s right to terminate in this Section 9.1 are non-refundable and shall be retained by Seller except for the Two-Hundred and Fifty
Thousand Dollars ($250,000.00) paid upon production of the first batch of non-clinical grade SPUS by Buyer which shall be governed by the terms of the Escrow Agreement. 

9.2 Continuing Effectiveness. 

If this Agreement shall be terminated as herein set forth, both parties agree that they will remain obligated under, and
will comply with, the provisions of Article 8 and Sections 1.1, 10.2, 10.3, 10.4, 10.7, 10.9, 10.10 and 10.11. 
 ARTICLE 10 
 Miscellaneous 

10.1 Assignment. 
 This Agreement shall be binding upon and inure to the benefit of the parties hereto and their respective successors and assigns; provided, however, that no assignment shall be made by either
party without the prior express written consent of the other party. Notwithstanding the foregoing, either party may assign its rights and obligations under this Agreement without such consent in connection with the transfer or sale of all or
substantially all of its business to which this Agreement relates to a third party, whether by merger, sale of stock, sale of assets or otherwise, provided that such third party assumes in writing all of such party’s obligations under this
Agreement. Any assignment not in accordance with this Agreement shall be void. 

  
 13 

 10.2 No Press Release Without Consent. No press release related to
this Agreement or the transactions contemplated herein, or other announcement to either the customers or suppliers of Seller or investors or potential investors in Buyer will be issued without the joint approval of Seller and Buyer, except any
public disclosure which Seller or Buyer in its good faith judgment believes is required by law, rule or regulation or by any stock exchange or interdealer quotation system on which its securities are listed or quoted (in which case the party making
the disclosure will use its reasonable best efforts to consult with the other party prior to making any such disclosure). 
 10.3 Confidentiality. 
 All nonpublic proprietary or
confidential information gained by either party concerning the other as a result of the transactions contemplated hereby (“Confidential Information”), including the execution and consummation of the transactions contemplated hereby
and the terms thereof, will be kept in strict confidence, subject to disclosures permitted pursuant to Section 10.2. All Confidential Information will be used only for the purpose of consummating the transactions contemplated hereby. Following
the Closing, all Confidential Information relating to the Purchased Assets disclosed by Seller to Buyer shall become the Confidential Information of Buyer, subject to the restrictions on use and disclosure by Seller imposed under this
Section 10.3. Neither Seller nor Buyer shall, without having previously informed the other party about the form, content and timing of any such announcement, make any public disclosure with respect to the Confidential Information or
transactions contemplated hereby, except As may be required by (a) law, rule or regulation, (b) the Securities and Exchange Commission (the “SEC”), (c) the Securities Act or the Exchange Act, or (d) any listing
agreement with the NASDAQ Stock Market, the National Association of Securities Dealers, Inc. or any national securities exchange to which Seller or Buyer as applicable, is subject; provided that, in any such event, the party required to make
the disclosure will (I) provide the other party with prompt written notice of any such requirement so that such other party may seek a protective order or other appropriate remedy, (II) consult with and exercise in good faith all reasonable
efforts to mutually agree with the other party regarding the nature, extent and form of such disclosure, (III) limit disclosure of Confidential Information to what is legally required to be disclosed, and (IV) exercise its best efforts to preserve
the confidentiality of any such Confidential Information. 
 10.4 Expenses. 

Each party shall bear its own expenses with respect to the transactions contemplated by this Agreement. 

10.5 Severability. 
 Each of the provisions contained in this Agreement shall be severable, and the unenforceability of one shall not affect the enforceability of any others or of the remainder of this Agreement. 

  
 14 

 10.6 Entire Agreement. 

This Agreement may not be amended, supplemented or otherwise modified except by an instrument in writing signed by all of
the parties hereto. This Agreement, the Other Agreements and the Confidentiality Agreement contain the entire agreement of the parties hereto with respect to the transactions covered hereby, superseding all negotiations, prior discussions and
preliminary agreements made prior to the date hereof. 
 10.7 No Third Party Beneficiaries. 

This Agreement is for the sole benefit of the parties hereto and their permitted assigns and nothing herein, express or
implied shall give or be construed to give to any Person, other than the parties hereto and such permitted assigns, any legal or equitable rights hereunder. 
 10.8 Waiver. 
 The failure of any party to enforce any
condition or part of this Agreement at any time shall not be construed as a waiver of that condition or part, nor shall it forfeit any rights to future enforcement thereof. Any waiver hereunder shall be effective only if delivered to the other party
hereto in writing by the party making such waiver. 
 10.9 Further Documents. 

Each of Buyer and Seller will, at the request of another party, execute and deliver to such other party all such further
instruments, assignments, assurances and other documents as such other party may reasonably request in connection with the carrying out of this Agreement and the transactions contemplated hereby. 

10.10 Notices. 
 All communications, notices and consents provided for herein shall be in writing and be given in person or by means of telex, facsimile or other means of wire transmission (with request for assurance of
receipt in a manner typical with respect to communications of that type), by overnight courier or by mail, and shall become effective: (a) on delivery if given in person; (b) on the date of transmission if sent by telex, facsimile or other
means of wire transmission; (c) one (1) business day after delivery to the overnight service; or (d) four (4) business days after being mailed, with proper postage and documentation, for first-class registered or certified mail,
prepaid. 
 Notices shall be addressed as follows: 

If to Buyer, to: 

World Heart Corporation 

4750 Wiley Post Way, Suite 120 

Salt Lake City, UT 84116 

Attn: Morgan Brown, Chief Financial Officer 

  
 15 

 If to Seller, to: 

SynCardia Systems, Inc. 

1992 E. Silverlake 

Tucson, AZ 85713 

Attn: Dena Richter, Chief Financial Officer 

provided, however, at the time of mailing or within three business days thereafter there is or occurs a labor dispute or
other event that might reasonably be expected to disrupt the delivery of documents by mail, any communication, notice or consent provided for herein shall be given in person or by means of telex, facsimile or other means of wire transmission or by
overnight courier, and further provide that if any party shall have designated a different address by notice to the others, then to the last address so designated. 

10.11 Governing Law. 
 This Agreement shall be construed and enforced in accordance with and governed by the laws of the State of Utah without regard to the conflicts of laws provisions thereof. 

10.12 Headings. 
 The headings of the sections and subsections of this Agreement are inserted for convenience only and shall not be deemed to constitute a part hereof. 

10.13 Counterparts. 
 The parties may execute this Agreement in counterparts, each of which shall constitute an original and all of which, when taken together, shall constitute one agreement. The exchange of a fully executed
agreement (in counterparts or otherwise) by electronic transmission or by facsimile shall be sufficient to bind the parties to the terms and conditions of this Agreement. 
 * * * * * * * * * * * 

  
 16 

 IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be
executed by their respective duly authorized officers as of the date first above written. 
  

			
	 WORLD HEART CORPORATION

		
	 By:
	 	 /s/ Morgan R. Brown        

	 Name:
	 	 Morgan R. Brown

	 Title:
	 	 Chief Financial Officer

	  
 SYNCARDIA SYSTEMS,
INC.

		
	 By:
	 	 /s/ Dena Richter            

	 Name:
	 	 Dena Richter

	 Title:
	 	 Chief Financial Officer

  
 17 

  
 Schedule 2.1(d)
SPUS Lots 
  

							
	Viscosity Spec:	  	150,000 - 280,000	  	 	  	 
	 SynCardia Lot #
	  	WorldHeart Lot #	  	Exp Date    	  	Result      
  
	 23785
	  	1223080901	  	12/23/2013	  	400000 cPs
	 23784
	  	1216080901	  	12/16/2013	  	124000 cPs
	
23788
	  	129090901	  	1/29/2014	  	300000 cPs

 Schedule 2.1(e) - Raw Materials 

PTMEG 1800 (2-400KG drums) 

 EXHIBIT A 

BILL OF SALE, CONVEYANCE AND ASSIGNMENT 

THIS BILL OF SALE, CONVEYANCE AND ASSIGNMENT (this “Instrument”) dated as of July 11, 2011, is made
by and between WORLD HEART CORPORATION, a corporation organized and existing under the laws of the State of Delaware (herein referred to as “Seller”) and SYNCARDIA SYSTEMS, INC., a corporation existing under the laws of the State of
Delaware (herein referred to as “Buyer”) and is delivered pursuant to, and subject to the terms of, that certain Asset Purchase Agreement, dated as of July 11, 2011 (the “Asset Purchase Agreement”), by and
between Seller and Buyer. 
 NOW, THEREFORE, subject to the terms and conditions of the Asset Purchase Agreement
and for the consideration set forth therein, Buyer and Seller each hereby agrees as follows: 
  

	 1.
	 Seller does hereby sell, convey, transfer, assign and deliver to Buyer, all of its right, title and interest in the Purchased Assets.

  

	 2.
	 From time to time, as and when reasonably requested by Buyer, Seller shall execute and deliver all such documents and instruments and shall take, or
cause to be taken, all such further or other actions as Buyer may reasonably deem necessary or desirable to more effectively sell, transfer, convey and assign to Buyer all of Seller’s right, title and interest in the Purchased Assets subject to
this Instrument. 

  

	 3.
	 This Instrument shall be governed by and construed in accordance with the internal laws of the State of Utah applicable to agreements made and to be
performed entirely within such State, without regard to the conflicts of laws principles of such State. 

  

	 4.
	 To the extent that any provision of this Instrument is inconsistent or conflicts with the Asset Purchase Agreement, the provisions of the Asset
Purchase Agreement shall control. Nothing in this Instrument, express or implied, is intended or shall be construed to expand or defeat, impair or limit in any way the rights, obligations, claims or remedies of the parties as set forth in the Asset
Purchase Agreement. 

  

	 5.
	 This Instrument may be executed in any number of counterparts, each of which when executed and delivered shall be deemed to be an original and all
of which when taken together shall constitute but one and the same instrument. 

  

	 6.
	 Unless otherwise provided for, capitalized terms set forth herein shall have the meaning ascribed to them in the Asset Purchase Agreement.

 IN WITNESS WHEREOF, this Instrument is duly executed and delivered as of the
date and year first above written. 
  

			
	 WORLD HEART CORPORATION

		
	 By
	 	 /s/ Morgan R. Brown

	 Name:
	 	 Morgan R. Brown

	 Title: Chief Financial Officer

	
	 SYNCARDIA SYSTEMS, INC.

		
	 By:
	 	 /s/ Dena Richter

	 Name:
	 	 Dena Richter

	 Title: Chief Financial Officer

 Exhibit B 

ESCROW AGREEMENT 
 (Basic Three Party Escrow) 
 THIS ESCROW AGREEMENT
(as the same may be amended or modified from time to time pursuant hereto, this “Agreement”) is made and entered into as of October 20, 2011, by and amongWorld Heart Corporation, a Delaware corporation (“Party A”), SynCardia
Systems, Inc., a Delaware corporation (“Party B”, and together with Party A, sometimes referred to individually as “Party” or collectively as the “Parties”), and JPMorgan Chase Bank, National Association (the
“Escrow Agent”). 
 WHEREAS, the Parties have agreed to deposit in escrow certain funds and wish such deposit
to be subject to the terms and conditions set forth herein. 
 NOW THEREFORE, in consideration of the foregoing and of
the mutual covenants hereinafter set forth, the parties hereto agree as follows: 
 1. Appointment. The Parties hereby
appoint the Escrow Agent as their escrow agent for the purposes set forth herein, and the Escrow Agent hereby accepts such appointment under the terms and conditions set forth herein. 

2. Fund. Party B agrees to deposit with the Escrow Agent the sum of $250,000 (the “Escrow Deposit”). The Escrow Agent
shall hold the Escrow Deposit and, subject to the terms and conditions hereof, shall invest and reinvest the Escrow Deposit and the proceeds thereof (the “Fund”) as directed in Section 3. 

3. Investment of Fund. During the term of this Agreement, the Fund shall be invested in a Money Market Deposit Account
(“MMDA”) MMDA have rates of compensation that may vary from time to time based upon market conditions. Instructions to make any other investment (“Alternative Investment”), must be in writing and shall specify the type and
identity of the investments to be purchased and/or sold. The Escrow Agent is hereby authorized to execute purchases and sales of investments through the facilities of its own trading or capital markets operations or those of any affiliated entity.
The Escrow Agent or any of its affiliates may receive compensation with respect to any Alternative Investment directed hereunder including without limitation charging any applicable agency fee in connection with each transaction. The Parties
recognize and agree that the Escrow Agent will not provide supervision, recommendations or advice relating to either the investment of moneys held in the Fund or the purchase, sale, retention or other disposition of any investment described herein.
The Escrow Agent shall not have any liability for any loss sustained as a result of any investment in an investment made pursuant to the terms of this Agreement or as a result of any liquidation of any investment prior to its maturity or for the
failure of the Parties to give the Escrow Agent instructions to invest or reinvest the Fund. The Escrow Agent shall have the right to liquidate any investments held in order to provide funds necessary to make required payments under this Agreement.

  
 22 

 4. Purpose, Disposition and Termination. (a) The purpose of this
Agreement and the Escrow Deposit is the fulfillment of the conditions set forth in Section 3.1(c) of the Asset Purchase Agreement dated July 11, 2011between Parties (the “APA”). 

(b) On or before March 15, 2012, Party A and Party B agree that they shall deliver to the Escrow Agent joint written instructions,
substantially in the form of either Exhibit C-1 or Exhibit C-2 hereto, executed by each of Party A and Party B (“Disbursement Instructions”) indicating that the entire Fund shall be paid out as set forth in such written
instructions, less any fees payable in connection with this Escrow. 
 (c) In the event the Parties do not deliver such joint
written instructions by March 15, 2012, then Escrow Agent shall return the Fund, less any fess payable in connection with this Escrow, to Party B. 
 (d) Any requests to extend the dates noted in 4.(b) and 4.(c) require the written consent of the Escrow Agent and each of the Parties hereto. Such extension is not effective until confirmed in writing by
Escrow Agent. 
 5. Escrow Agent. (a) The Escrow Agent shall have only those duties as are specifically and
expressly provided herein, which shall be deemed purely ministerial in nature, and no other duties shall be implied. The Escrow Agent shall neither be responsible for, nor chargeable with, knowledge of, nor have any requirements to comply with, the
terms and conditions of any other agreement, instrument or document between the Parties, in connection herewith, if any, including without limitation the APA (each an “Underlying Agreement”), nor shall the Escrow Agent be
required to determine if any person or entity has complied with any Underlying Agreement, nor shall any additional obligations of the Escrow Agent be inferred from the terms of any Underlying Agreements, even though reference thereto may be made in
this Agreement. In the event of any conflict between the terms and provisions of this Agreement, those of any Underlying Agreement, any schedule or exhibit attached to the Agreement, or any other agreement among the Parties, the terms and
conditions of this Agreement shall control. The Escrow Agent may rely upon and shall not be liable for acting or refraining from acting upon any written notice, document, instruction or request furnished to it hereunder and believed by it to be
genuine and to have been signed or presented by the proper Party or Parties without inquiry and without requiring substantiating evidence of any kind. The Escrow Agent shall not be liable to any Party, any beneficiary or other person for refraining
from acting upon any instruction setting forth, claiming, containing, objecting to, or related to the transfer or distribution of the Fund, or any portion thereof, unless such instruction shall have been delivered to the Escrow Agent in accordance
with Section 11 below and the Escrow Agent has been able to satisfy any applicable security procedures as may be required thereunder. The Escrow Agent shall be under no duty to inquire into or investigate the validity, accuracy or content of
any such document, notice, instruction or request. The Escrow Agent shall have no duty to solicit any payments which may be due it or the Fund, including, without limitation, the Escrow Deposit nor shall the Escrow Agent have any duty or obligation
to confirm or verify the accuracy or correctness of any amounts deposited with it hereunder. 

  
 23 

 (b) The Escrow Agent shall not be liable for any action taken, suffered or omitted to be
taken by it in good faith except to the extent that a final adjudication of a court of competent jurisdiction determines that the Escrow Agent’s gross negligence or willful misconduct was the primary cause of any loss to either Party. The
Escrow Agent may execute any of its powers and perform any of its duties hereunder directly or through affiliates or agents. The Escrow Agent may consult with counsel, accountants and other skilled persons to be selected and retained by it. The
Escrow Agent shall not be liable for any action taken, suffered or omitted to be taken by it in accordance with, or in reliance upon, the advice or opinion of any such counsel, accountants or other skilled persons. In the event that the Escrow Agent
shall be uncertain or believe there is some ambiguity as to its duties or rights hereunder or shall receive instructions, claims or demands from any Party hereto which, in its opinion, conflict with any of the provisions of this Agreement, it shall
be entitled to refrain from taking any action and its sole obligation shall be to keep safely all property held in escrow until it shall be given a direction in writing by the Parties which eliminates such ambiguity or uncertainty to the
satisfaction of Escrow Agent or by a final and non-appealable order or judgment of a court of competent jurisdiction. The Parties agree to pursue any redress or recourse in connection with any dispute without making the Escrow Agent a party to the
same. Anything in this Agreement to the contrary notwithstanding, in no event shall the Escrow Agent be liable for special, incidental, punitive, indirect or consequential loss or damage of any kind whatsoever (including but not limited to lost
profits), even if the Escrow Agent has been advised of the likelihood of such loss or damage and regardless of the form of action. 
 6. Succession. (a) The Escrow Agent may resign and be discharged from its duties or obligations hereunder by giving thirty (30) days advance notice in writing of such resignation to the
Parties specifying a date when such resignation shall take effect. If the Parties have failed to appoint a successor escrow agent prior to the expiration of thirty (30) days following receipt of the notice of resignation, the Escrow Agent may
petition any court of competent jurisdiction for the appointment of a successor escrow agent or for other appropriate relief, and any such resulting appointment shall be binding upon all of the parties hereto. Escrow Agent’s sole responsibility
after such thirty (30) day notice period expires shall be to hold the Fund (without any obligation to reinvest the same) and to deliver the same to a designated substitute escrow agent, if any, or in accordance with the directions of a final
order or judgment of a court of competent jurisdiction, at which time of delivery Escrow Agent’s obligations hereunder shall cease and terminate, subject to the provisions of Section 8(b). In accordance with Section 8(b), the Escrow
Agent shall have the right to withhold an amount equal to any amount due and owing to the Escrow Agent, plus any costs and expenses the Escrow Agent shall reasonably believe may be incurred by the Escrow Agent in connection with the termination of
the Agreement. 
 (b) Any entity into which the Escrow Agent may be merged or converted or with which it may be consolidated, or
any entity to which all or substantially all the escrow business may be transferred, shall be the Escrow Agent under this Agreement without further act. 

  
 24 

 7. Compensation and Reimbursement. The Parties agree jointly and severally
(a) to pay the Escrow Agent upon execution of this Agreement and from time to time thereafter reasonable compensation for the services to be rendered hereunder, along with any fees or charges for accounts, including those levied by any
governmental authority which the Escrow Agent may impose, charge or pass-through, which unless otherwise agreed in writing shall be as described in Schedule 2 attached hereto, and (b) to pay or reimburse the Escrow Agent upon request for all
expenses, disbursements and advances, including, without limitation reasonable attorney’s fees and expenses, incurred or made by it in connection with the performance, modification and termination of this Agreement. The obligations contained in
this Section 7 shall survive the termination of this Agreement and the resignation, replacement or removal of the Escrow Agent. 
 8. Indemnity. (a) The Parties shall jointly and severally indemnify, defend and hold harmless the Escrow Agent and its affiliates and their respective successors, assigns, directors, agents
and employees (the “Indemnitees”) from and against any and all losses, damages, claims, liabilities, penalties, judgments, settlements, litigation, investigations, costs or expenses (including, without limitation, the fees and expenses of
outside counsel and experts and their staffs and all expense of document location, duplication and shipment)(collectively “Losses”) arising out of or in connection with (i) the Escrow Agent’s execution and performance of this
Agreement, tax reporting or withholding, the enforcement of any rights or remedies under or in connection with this Agreement, or as may arise by reason of any act, omission or error of the Indemnitee, except in the case of any Indemnitee to the
extent that such Losses are finally adjudicated by a court of competent jurisdiction to have been primarily caused by the gross negligence or willful misconduct of such Indemnitee, or (ii) its following any instructions or directions, whether
joint or singular, from the Parties, except to the extent that its following any such instruction or direction is expressly forbidden by the terms hereof. The indemnity obligations set forth in this Section 8(a) shall survive the resignation,
replacement or removal of the Escrow Agent or the termination of this Agreement. 
 (b) The Parties hereby grant the Escrow
Agent a lien on, right of set-off against and security interest in, the Fund for the payment of any claim for indemnification, fees, expenses and amounts due to the Escrow Agent or an Indemnitee. In furtherance of the foregoing, the Escrow Agent is
expressly authorized and directed, but shall not be obligated, to charge against and withdraw from the Fund for its own account or for the account of an Indemnitee any amounts due to the Escrow Agent or to an Indemnitee under either Sections 6(a), 7
or 8(a) of this Agreement. 
  

	 9.
	 Patriot Act Disclosure/Taxpayer Identification Numbers/Tax Reporting.  

(a) Patriot Act Disclosure. Section 326 of the Uniting and Strengthening America by Providing Appropriate Tools Required to
Intercept and Obstruct Terrorism Act of 2001 (“USA PATRIOT Act”) requires the Escrow Agent to implement reasonable procedures to verify the identity of any person that opens a new account with it. Accordingly, the Parties acknowledge that
Section 326 of the USA PATRIOT Act and the Escrow Agent’s identity verification procedures require the Escrow Agent to obtain information which may be used to confirm the Parties identity including without limitation name, address and
organizational documents (“identifying 

  
 25 

 information”). The Parties agree to provide the Escrow Agent with and consent to the
Escrow Agent obtaining from third parties any such identifying information required as a condition of opening an account with or using any service provided by the Escrow Agent. 

(b) Certification and Tax Reporting. The Parties have provided the Escrow Agent with their respective fully executed Internal
Revenue Service (“IRS”) Form W-8, or W-9 and/or other required documentation. All interest or other income earned under this Agreement shall be allocated to Party A and reported, as and to the extent required by law, by the Escrow Agent to
the IRS, or any other taxing authority, on IRS Form 1099 or 1042S (or other appropriate form) as income earned from the Escrow Deposit by Party A whether or not said income has been distributed during such year. Escrow Agent shall withhold any taxes
it deems appropriate in the absence of proper tax documentation or as required by law, and shall remit such taxes to the appropriate authorities. The Parties hereby represent to the Escrow Agent that (i) there is no sale or transfer of an
United States Real Property Interest as defined under IRC Section 897(c) in the underlying transaction giving rise to this Agreement; and (ii) such underlying transaction does not constitute an installment sale requiring tax reporting or
withholding of imputed interest or original issue discount to the IRS or other taxing authority. 
 10. Notices. All
communications hereunder shall be in writing and except for communications from the Parties setting forth, claiming, containing, objecting to, or in any way related to the transfer or distribution of funds, including but not limited to funds
transfer instructions (all of which shall be specifically governed by Section 11 below), shall be deemed to be duly given after it has been received and the receiving party has had a reasonable time to act upon such communication if it is sent
or served: 
 (a) by facsimile; 

(b) by overnight courier; or 
 (c) by prepaid registered mail, return receipt requested; 
 to the appropriate
notice address set forth below or at such other address as any party hereto may have furnished to the other parties in writing by registered mail, return receipt requested. 
 If to Party A 
 World Heart Corporation 

4750 Wiley Post Way, Suite 120 
 Salt Lake City, UT 84116 
 Attn: Morgan Brown, Chief Financial
Officer 
 Tel No.: 801-303-4361 

Fax No.: 801-413-0546 
 If to Party B 
 Syncardia Systems, Inc. 

1992 E. Silverlake 
 Tucson, AZ 85713: 

  
 26 

 Attn:_Deanna Richter 

Tel No.: 520-547-7469 
 Fax No.: 520-903-1782 
 If to the Escrow Agent 

JPMorgan Chase Bank, N.A. 
 333 South Grand Avenue, Floor 36 
 Los Angeles CA 90071-1504

 Attn: Barbara Mitchell, Escrow Services 

Fax No.: 213-621-8090 
 Notwithstanding the above, in the case of communications delivered to the Escrow Agent, such communications shall be deemed to have been given on the date received by an officer of the Escrow Agent or any
employee of the Escrow Agent who reports directly to any such officer at the above-referenced office. In the event that the Escrow Agent, in its sole discretion, shall determine that an emergency exists, the Escrow Agent may use such other means of
communication as the Escrow Agent deems appropriate. For purposes of this Agreement, “Business Day” shall mean any day other than a Saturday, Sunday or any other day on which the Escrow Agent located at the notice address set forth above
is authorized or required by law or executive order to remain closed. 
 11. Security Procedures. Notwithstanding
anything to the contrary as set forth in Section 10, any instructions setting forth, claiming, containing, objecting to, or in any way related to the transfer or distribution of funds, including but not limited to any such funds transfer
instructions that may otherwise be set forth in a written instruction permitted pursuant to Section 4 of this Agreement, may be given to the Escrow Agent only by confirmed facsimile and no instruction for or related to the transfer or
distribution of the Fund, or any portion thereof, shall be deemed delivered and effective unless the Escrow Agent actually shall have received such instruction by facsimile at the number provided to the Parties by the Escrow Agent in accordance with
Section 10 and as further evidenced by a confirmed transmittal to that number. 
 (a) In the event funds transfer
instructions are so received by the Escrow Agent by facsimile, the Escrow Agent is authorized to seek confirmation of such instructions by telephone call-back to the person or persons designated on Schedule 1 hereto, and the Escrow Agent may rely
upon the confirmation of anyone purporting to be the person or persons so designated. The persons and telephone numbers for call-backs may be changed only in a writing actually received and acknowledged by the Escrow Agent. If the Escrow Agent is
unable to contact any of the authorized representatives identified in Schedule 1, the Escrow Agent is hereby authorized both to receive written instructions from and seek confirmation of such instructions by telephone call-back to any one or more of
Party A or Party B’s executive officers, (“Executive Officers”), as the case may be, which shall include the titles of President, CEO or CFO, as the Escrow Agent may select. Such “Executive Officer” shall deliver to the
Escrow Agent a fully executed incumbency certificate, and the Escrow Agent may rely upon the confirmation of anyone purporting to be any such officer. The Escrow Agent and the beneficiary’s bank in any funds transfer may rely solely upon any
account numbers or similar identifying numbers provided by Party A or Party B to identify (i) the beneficiary, (ii) the beneficiary’s bank, or (iii) an intermediary bank. The Escrow Agent may apply any of the Fund for any payment
order it executes using any such identifying number, even when its use may result in a person other than the beneficiary being paid, or the transfer of funds to a bank other than the beneficiary’s bank or an intermediary bank designated.

  
 27 

 (b) The Parties acknowledge that the security procedures set forth in this
Section 11are commercially reasonable. 
 12. Compliance with Court Orders. In the event that any escrow property
shall be attached, garnished or levied upon by any court order, or the delivery thereof shall be stayed or enjoined by an order of a court, or any order, judgment or decree shall be made or entered by any court order affecting the property deposited
under this Agreement, the Escrow Agent is hereby expressly authorized, in its sole discretion, to obey and comply with all writs, orders or decrees so entered or issued, which it is advised by legal counsel of its own choosing is binding upon it,
whether with or without jurisdiction, and in the event that the Escrow Agent obeys or complies with any such writ, order or decree it shall not be liable to any of the parties hereto or to any other person, entity, firm or corporation, by reason of
such compliance notwithstanding such writ, order or decree be subsequently reversed, modified, annulled, set aside or vacated. 

13. Miscellaneous. Except for changes to funds transfer instructions as provided in Section 11, the provisions of this
Agreement may be waived, altered, amended or supplemented, in whole or in part, only by a writing signed by the Escrow Agent and the Parties. Neither this Agreement nor any right or interest hereunder may be assigned in whole or in part by the
Escrow Agent or any Party, except as provided in Section 6, without the prior consent of the Escrow Agent and the other Parties. This Agreement shall be governed by and construed under the laws of the State of New York. Each Party and the
Escrow Agent irrevocably waives any objection on the grounds of venue, forum non-conveniens or any similar grounds and irrevocably consents to service of process by mail or in any other manner permitted by applicable law and consents to the
jurisdiction of the courts located in the State of California. To the extent that in any jurisdiction either Party may now or hereafter be entitled to claim for itself or its assets, immunity from suit, execution attachment (before or after
judgment), or other legal process, such Party shall not claim, and it hereby irrevocably waives, such immunity. The Escrow Agent and the Parties further hereby waive any right to a trial by jury with respect to any lawsuit or judicial proceeding
arising or relating to this Agreement. No party to this Agreement is liable to any other party for losses due to, or if it is unable to perform its obligations under the terms of this Agreement because of, acts of God, fire, war, terrorism, floods,
strikes, electrical outages, equipment or transmission failure, or other causes reasonably beyond its control. This Agreement may be executed in one or more counterparts, each of which shall be deemed an original, but all of which together shall
constitute one and the same instrument. All signatures of the parties to this Agreement may be transmitted by facsimile, and such facsimile will, for all purposes, be deemed to be the original signature of such party whose signature it reproduces,
and will be binding upon such party. If any provision of this Agreement is determined to be prohibited or unenforceable by reason of any applicable law of a jurisdiction, then such provision shall, as to such jurisdiction, be ineffective to the
extent of such prohibition or unenforceability without invalidating the remaining provisions thereof, and any such prohibition or unenforceability in such jurisdiction shall not invalidate or render unenforceable such provisions in any other
jurisdiction. A person who is not a party to this Agreement shall have no right to enforce any term of this Agreement. The Parties represent, warrant and covenant that each 

  
 28 

 document, notice, instruction or request provided by such Party to Escrow Agent shall comply
with applicable laws and regulations. Where, however, the conflicting provisions of any such applicable law may be waived, they are hereby irrevocably waived by the parties hereto to the fullest extent permitted by law, to the end that this
Agreement shall be enforced as written. Except as expressly provided in Section 8 above, nothing in this Agreement, whether express or implied, shall be construed to give to any person or entity other than the Escrow Agent and the Parties any
legal or equitable right, remedy, interest or claim under or in respect of this Agreement or any funds escrowed hereunder. 

  
 29 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date
set forth above. 
 PARTY A – WORLD HEART CORPORATION 

By: /s/ Morgan R. Brown 
 Name: Morgan R. Brown 
 Title: Chief Financial Officer 

PARTY B – SYNCARDIA SYSTEMS, INC. 
 By: /s/ Michael Garippa 
 Name: Michael Garippa 

Title: Chief Executive Officer 
 JPMORGAN CHASE BANK, NATIONAL ASSOCIATION 
 as Escrow Agent

 By: /s/ Barbara C Mitchell 
 Name: Barbara C Mitchell 
 Title: Vice President 

  
 30 

         (A)
SCHEDULE 1 
 Page 1 
 (b) Telephone Number(s) and authorized signature(s) for     

(c) Person(s) Designated to give Funds Transfer Instructions 

If from Party A: 
  

					
	             Name
	  	 Telephone Number
	  	 Signature

			
	 1.   Alex Martin_________________________
	  	801-303-4352	  	
			
	
            ______________________________
	  		  	
			
	 2.   Morgan Brown_____________________
	  	801-303-4361	  	
			
	
            ______________________________
	  		  	
		
	 3.  _________________________________
	  	 ____________________

			
	
            ______________________________
	  		  	
			
	 If from Party B:
	  		  	
			
	       Name
	  	 Telephone Number
	  	 Signature

			
	 1.   Michael Garippa
	  	 520-545-1234
	  	 _____________________

			
	 2.   Dena Richter
	  	 520-545-1234
	  	 _____________________

			
	 3.   David Mackstaller
	  	 520-545-`234
	  	 _____________________

	
	 (d) Telephone Number(s) for Call-Backs and

	
	Person(s) Designated to Confirm Funds Transfer Instructions
			
	 If from Party A:
	  		  	
			
	             Name
	  	 Telephone Number
	  	 
			
	 1.   Alex Martin
	  	 801-303-4352
	  	
			
	 2.   Morgan Brown
	  	 801-303-4361
	  	
		
	 3.  _________________________________
	  	 _______________________

  
 31 

 If from Party B: 

 

					
	             Name
	  	 Telephone Number
	  	 
			
	 1.   Michael Garippa
	  	 520-545-1234
	  	
			
	 2.   Dena Richter
	  	 520-545-1234
	  	
			
	 3.   David Mackstaller
	  	 520-545-`234
	  	

            (i) SCHEDULE 2

  
 

 
  
 

 
 Based upon our current understanding of your proposed transaction, our fee proposal is
as follows: 
 Account Acceptance Fee . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....$ WAIVED

 Encompassing review, negotiation and execution of governing documentation, opening of the account, and completion of all
due diligence documentation. Payable upon closing. 
 Annual Administration Fee . . . . . . . . . . . . . . . . . . . . .
.. . . . . . . . . . . . $ 2,500 
 The Administration Fee covers our usual and customary ministerial duties, including
record keeping, distributions, document compliance and such other duties and responsibilities expressly set forth in the governing documents for each transaction. Payable upon closing and annually in advance thereafter, without pro-ration for
partial years. 
 Extraordinary Services and Out-of Pocket Expenses 

Any additional services beyond our standard services as specified above, and all reasonable out-of-pocket expenses including
attorney’s or accountant’s fees and expenses will be considered extraordinary services for which related costs, transaction charges, and additional fees will be billed at the Bank’s then standard rate. Disbursements, receipts,
investments or tax reporting exceeding 25 items per year may be treated as extraordinary services thereby incurring additional charges. The Escrow Agent may impose, charge, pass-through and modify fees and/or charges for any account
established and services provided by the Escrow Agent, including but not limited to, transaction, maintenance, balance-deficiency, and service fees and other charges, including those levied by any governmental authority. 

  
 32 

 Disclosure & Assumptions 

	 —
	 Please note that the fees quoted are based on a review of the transaction documents provided and an internal due diligence review. JPMorgan reserves
the right to revise, modify, change and supplement the fees quoted herein if the assumptions underlying the activity in the account, level of balances, market volatility or conditions or other factors change from those used to set our fees.

  

	 —
	 The escrow deposit shall be continuously invested in a JPMorgan Chase Bank money market deposit account (“MMDA”) or a JPMorgan Chase Bank
Cash Compensation account. MMDA and Cash Compensation Accounts have rates of compensation that may vary from time to time based upon market conditions. The Annual Administration Fee would include a supplemental charge up to 25 basis points on the
escrow deposit amount if another investment option were to be chosen. 

  

	 —
	 The Parties acknowledge and agree that they are permitted by U.S. law to make up to six (6) pre-authorized withdrawals or telephonic transfers
from an MMDA per calendar month or statement cycle or similar period. If the MMDA can be accessed by checks, drafts, bills of exchange, notes and other financial instruments (“Items”), then no more than three (3) of these six
(6) transfers may be made by an Item. The Escrow Agent is required by U.S. law to reserve the right to require at least seven (7) days notice prior to a withdrawal from a money market deposit account. 

 

	 —
	 Payment of the invoice is due upon receipt. 

 Compliance 
 To help the government fight the funding of terrorism and money
laundering activities, Federal law requires all financial institutions to obtain, verify, and record information that identifies each person or entity that opens an account. We may ask for information that will enable us to meet the requirements of
the Act. 

  
 33 

 EXHIBIT C-1 

(To be used upon achievement of condition 3.1(c) of the APA) 

JPMorgan Chase Bank, N.A. 
 333 South Grand Avenue, Floor 36 
 Los Angeles CA 90071-1504 

Attn: Barbara Mitchell, Escrow Services 
 Fax No.: 213-621-8090 
 Escrow Agreement dated:
                        , 2011 
 Party A: World Heart Corporation 
 Party B: SynCardia Systems, Inc. 

This letter is delivered pursuant to Section 4.(b) of the Escrow Agreement, by and among World Heart Corporation, SynCardia Systems,
Inc. and JPMorgan Chase Bank, N.A. as the Escrow Agent. 
 The conditions set forth in Section 3.1(c) of the APA requiring
the release of the Fund to World Heart Corporation have been satisfied. World Heart Corporation and SynCardia Systems, Inc. hereby instruct Escrow Agent to release the entire Fund, less any fees payable in connection with the Escrow, to World Heart
Corporation via wire per below. 
 Wire Transfer Instructions: 

			
		
	 Name on Account:
	 	
		 	  

		
	 Bank Name:
	 	
		 	  

		
	 Account Number:
	 	
		 	  

		
	 Bank ABA/Routing Number
	 	
		 	  

		
	 References:
	 	
		 	  

 The undersigned has caused its duly authorized representative to execute this letter as of the date
hereof. 

 Sincerely, 
  

					
	 WORLD HEART CORPORATION
	 		 	 SYNCARDIA SYSTEMS, INC.

			
	 By:
	 		 	 By:

			
	  
	 		 	  

			
	 Its:
	 		 	 Its:

			
	  
	 		 	  

			
	 Date:
	 		 	 Date:

			
	  
	 		 	  

 EXHIBIT C-2 

(To be used upon non-achievement of milestone 3.1(c) of the APA) 

JPMorgan Chase Bank, N.A. 
 333 South Grand Avenue, Floor 36 
 Los Angeles CA 90071-1504 

Attn: Barbara Mitchell, Escrow Services 
 Fax No.: 213-621-8090 
 Escrow Agreement dated:
                        , 2011 
 Party A: World Heart Corporation 
 Party B: SynCardia Systems, Inc. 

This letter is delivered pursuant to Section 4.(b) of the Escrow Agreement, by and among World Heart Corporation, SynCardia Systems,
Inc. and JPMorgan Chase Bank, N.A. as the Escrow Agent. 
 The conditions set forth in Section 3.1(c) of the APA requiring
the release of the Fund to World Heart Corporation have been not been satisfied. World Heart Corporation and SynCardia Systems, Inc. hereby instruct Escrow Agent to release the entire Fund, less any fees payable in connection with the Escrow, to
SynCardia Systems, Inc. via wire per below. 
 Wire Transfer Instructions: 

 

			
	 Name on Account:
	 	
		 	  

		
	 Bank Name:
	 	
		 	  

		
	 Account Number:
	 	
		 	  

		
	 Bank ABA/Routing Number
	 	
		 	  

		
	 References:
	 	
		 	  

 The undersigned has caused its duly authorized representative to execute this letter as of the date
hereof. 

 Sincerely, 
  

					
	 WORLD HEART CORPORATION
	 		 	 SYNCARDIA SYSTEMS, INC.

			
	 By:
	 		 	 By:

			
	  
	 		 	  

			
	 Its:
	 		 	 Its:

			
	  
	 		 	  

			
	 Date:
	 		 	 Date:

			
	  
	 		 	  

 AMENDMENT NO. 1 

TO 

ASSET PURCHASE AGREEMENT 
 THIS AMENDMENT NO. 1 TO ASSET PURCHASE AGREEMENT, dated as of September 23, 2011 (the “Effective Date”) is entered into by and between WORLD HEART CORPORATION, a Delaware corporation
(“Seller”), and SYNCARDIA SYSTEMS, INC., a Delaware corporation (“Buyer”). 

WHEREAS, Seller and Buyer previously entered into an Asset Purchase Agreement dated July 11, 2011 (the
“Purchase Agreement”); and 
 WHEREAS, the Parties desire to amend the Purchase Agreement as set forth
below. 
 NOW, THEREFORE, in consideration of the premises and mutual covenants, agreements and provisions
herein contained, the parties hereto agree as follows: 
 1. Section 7.3 of the Purchase Agreement is
hereby amended in its entirety as follows: 
 “7.3 Buyer Diligence Obligations. 

Upon execution of this Agreement, Buyer shall proceed with Commercially Reasonable Diligent Efforts to complete each of
the events triggering the additional payments to Seller set forth in Sections 3.1(b), (c) and (d) above. To that effect, Buyer shall accomplish the following obligations as part of its diligence obligations hereunder: 

(a) Buyer shall complete the installation of the Reactor at Buyer’s premises within forty-five
(45) days of the Effective Date. 
 (b) Buyer shall produce the first batch of
non-clinical grade SPUS within one hundred five (105) days of the Effective Date. 
 (c)
Buyer shall produce the first batch of clinical grade SPUS within one hundred and thirty-five (135) days of the Effective Date. 
 If Buyer fails to meet any of the foregoing diligence obligations, then, except to the extent such failure is not caused by Seller’s delay, action or inaction, upon the payment of the applicable
extension fee set forth below Seller will grant to Buyer, upon Buyer’s request, a one-time thirty (30) day extension of time to meet Buyer’s missed diligence commitment. The first request for a thirty (30) day extension of time
to meet Buyer’s diligence commitments shall require the payment of Sixty-Two Thousand Five Hundred Dollars ($62,500.00) by Buyer to Seller. The second request for a thirty (30) day extension of time to meet Buyer’s diligence
commitment shall require the payment of Seventy-Five Thousand Dollars ($75,000.00) by Buyer to Seller. Each subsequent thirty (30) day extension request will require the payment of One Hundred Thousand Dollars ($100,000.00) by Buyer to Seller.
If, at the end of any extension, Buyer has not achieved 

 
such diligence event, then Seller may exercise its rights to terminate this Agreement, require the return of Purchased Assets and retain monies paid to Buyer by Seller through the date of
termination in accordance with Article 9 below. For clarification, if Buyer makes payment to extend the time to meet a diligence commitment described in Section 7.3(a) or (b) for thirty (30) days as described above, thereafter
the time in which Buyer is required to meet all subsequent diligence commitments shall automatically be extended by thirty (30) days without additional payment. For example, if Buyer is unable to produce the first batch of non-clinical grade
SPUS within one hundred five (105) days of the Effective Date and makes the payment of sixty-two thousand five hundred dollars ($62,500.00) to extend the time to complete the installation of the Reactor to one hundred thirty five
(135) days from the Effective Date, the time in which Buyer must produce the first batch of non-clinical grade SPUS shall thereafter be one hundred thirty-five (135) days from the Effective Date and the time in which Buyer must produce the
first batch of clinical grade SPUS shall be one hundred sixty-five (165) days from the Effective Date. If, after the grant of the first thirty (30) day extension Buyer is not able to meet any of the revised diligence achievement dates and
desires to extend such date by another thirty (30) days, the extension fee for the second request shall be Seventy-five Thousand Dollars ($75,000.00) and the fee for any additional extensions shall be One Hundred Thousand Dollars ($100,000.00).
Seller has no obligation to grant Buyer more than one (1) extension per diligence obligation set forth above.” 
 2. All other terms of the Purchase Agreement remain in full force and effect. 
 3. Capitalized terms used herein, unless otherwise provided for, shall have the definition set forth in the Purchase Agreement for such terms. 

IN WITNESS WHEREOF, the parties hereto have caused this Amendment No. 1 to be executed by their respective duly
authorized officers as of the date first above written. 
  

					
	 WORLD HEART CORPORATION
	 	
			
	 By:
	 	 /s/  Morgan R. Brown
	 	
	 Name:
	 	 Morgan R. Brown
	 	
	 Title:
	 	 Chief Financial Officer
	 	

  

					
	 SYNCARDIA SYSTEMS, INC.
	 	
			
	 By:
	 	 /s/ Dena Richter
	 	
	 Name:
	 	 Dean Richter
	 	
	 Title:
	 	 Chief Financial Officer

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