Document:

Form of Indemnification Agreement

 Exhibit 10.17 
 INDEMNIFICATION AGREEMENT 
 THIS INDEMNIFICATION AGREEMENT (the “Agreement”) is made
and entered into as of                      between Targanta Therapeutics Corporation, a Delaware corporation (the
“Company”), and
                                        
(“Indemnitee”). 
 WHEREAS, highly competent persons have become more reluctant to serve corporations as directors and
officers or in other capacities unless they are provided with adequate protection through insurance or adequate indemnification against inordinate risks of claims and actions against them arising out of their service to and activities on behalf of
the corporation; 
 WHEREAS, it is essential to the Company to retain and attract as directors and officers the most capable persons
available; 
 WHEREAS, it is the express policy of the Company to indemnify its directors and officers so as to provide them with the maximum
possible protection permitted by law; 
 WHEREAS, Indemnitee does not regard the protection that may be available under the Company’s
insurance or certificate of incorporation as adequate in the present circumstances, and is not willing to serve as or remain as a director and an officer without adequate protection; and 
 WHEREAS, the Company desires Indemnitee to serve as a director and an officer of the Company; 
 NOW, THEREFORE, in consideration of Indemnitee’s agreement to serve as a director and an officer after the date hereof, the parties hereto agree as
follows: 
 1. Indemnity of Indemnitee. The Company hereby agrees to hold harmless and indemnify Indemnitee to the
fullest extent permitted by law, as such may be amended from time to time. In furtherance of the foregoing indemnification, and without limiting the generality thereof: 
 (a) Proceedings Other Than Proceedings by or in the Right of the Company. Indemnitee shall be entitled to the rights of
indemnification provided in this Section l(a) if, by reason of his Corporate Status (as hereinafter defined), the Indemnitee is, or is threatened to be made, a party to or participant in any Proceeding (as hereinafter defined) other than a
Proceeding by or in the right of the Company. Pursuant to this Section 1(a), Indemnitee shall be indemnified against all Expenses (as hereinafter defined), judgments, penalties, fines and amounts paid in settlement actually and
reasonably incurred by him, or on his behalf, in connection with such Proceeding or any claim, issue or matter therein, if the Indemnitee acted in good faith and in a manner the Indemnitee reasonably believed to be in or not opposed to the best
interests of the Company, and with respect to any criminal Proceeding, had no reasonable cause to believe the Indemnitee’s conduct was unlawful. 
 (b) Proceedings by or in the Right of the Company. Indemnitee shall be entitled to the rights of indemnification provided in this Section 1(b) if, by reason of his Corporate Status, the Indemnitee
is, or is threatened to be made, a party to or participant in any 

 
Proceeding brought by or in the right of the Company. Pursuant to this Section 1(b), Indemnitee shall be indemnified against all Expenses
actually and reasonably incurred by the Indemnitee, or on the Indemnitee’s behalf, in connection with such Proceeding if the Indemnitee acted in good faith and in a manner the Indemnitee reasonably believed to be in or not opposed to the best
interests of the Company; provided, however, if applicable law so provides, no indemnification against such Expenses shall be made in respect of any claim, issue or matter in such Proceeding as to which Indemnitee shall have been
adjudged to be liable to the Company unless and to the extent that the Court of Chancery of the State of Delaware shall determine that such indemnification may be made. 
 (c) Indemnification for Expenses of a Party Who is Wholly or Partly Successful. Notwithstanding any other provision of this
Agreement, to the extent that Indemnitee is, by reason of his Corporate Status, a party to and is successful, on the merits or otherwise, in any Proceeding, he shall be indemnified to the maximum extent permitted by law, as such may be amended from
time to time, against all Expenses actually and reasonably incurred by him or on his behalf in connection therewith. If Indemnitee is not wholly successful in such Proceeding but is successful, on the merits or otherwise, as to one or more but less
than all claims, issues or matters in such Proceeding, the Company shall indemnify Indemnitee against all Expenses actually and reasonably incurred by him or on his behalf in connection with each successfully resolved claim, issue or matter. For
purposes of this Section and without limitation, the termination of any claim, issue or matter in such a Proceeding by dismissal, with or without prejudice, shall be deemed to be a successful result as to such claim, issue or matter. 
 2. Indemnification for Expenses of a Witness. Notwithstanding any other provision of this Agreement, to the extent that Indemnitee
is, by reason of his Corporate Status, a witness in any Proceeding to which Indemnitee is not a party, he shall be indemnified against all Expenses actually and reasonably incurred by him or on his behalf in connection therewith. 
 3. Advancement of Expenses. Notwithstanding any other provision of this Agreement, the Company shall advance all Expenses incurred
by or on behalf of Indemnitee in connection with any Proceeding by reason of Indemnitee’s Corporate Status within thirty (30) days after the receipt by the Company of a statement or statements from Indemnitee requesting such advance or
advances from time to time, whether prior to or after final disposition of such Proceeding. Such statement or statements shall reasonably evidence the Expenses incurred by Indemnitee and shall include or be preceded or accompanied by an undertaking
by or on behalf of Indemnitee to repay any Expenses advanced if it shall ultimately be determined that Indemnitee is not entitled to be indemnified against such Expenses. Any advances and undertakings to repay pursuant to this Section 3
shall be unsecured and interest free. 
 4. Procedures and Presumptions for Determination of Entitlement to
Indemnification. It is the intent of this Agreement to secure for Indemnitee rights of indemnity that are as favorable as may be permitted under the Delaware General Corporation Law and public policy of the State of Delaware. Accordingly, the
parties agree that the following procedures and presumptions shall apply in the event of any question as to whether Indemnitee is entitled to indemnification under this Agreement: 
 (a) To obtain indemnification under this Agreement, Indemnitee shall submit to the Company a written request, including therein or
therewith such documentation and information as is reasonably available to Indemnitee and is reasonably necessary to determine 

  

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whether and to what extent Indemnitee is entitled to indemnification. The Secretary of the Company shall, promptly upon receipt of such a request for
indemnification, advise the Board of Directors in writing that Indemnitee has requested indemnification. 
 (b) Upon written
request by Indemnitee for indemnification pursuant to the first sentence of Section 4(a) hereof, a determination, if required by applicable law, with respect to Indemnitee’s entitlement thereto shall be made in the specific case by
one of the following four methods, which choice of method shall be at the election of the Company’s Board of Directors: (1) by a majority vote of the Disinterested Directors (as defined in Section 11 hereof), even though less
than a quorum, (2) by a committee of Disinterested Directors designated by a majority vote of the Disinterested Directors, even though less than a quorum, (3) if there are no Disinterested Directors or if the Disinterested Directors so
direct, by Independent Counsel (as defined in Section 11 hereof) in a written opinion to the Board of Directors, a copy of which shall be delivered to the Indemnitee, or (4) if so directed by the Board of Directors, by the
stockholders of the Company. 
 (c) If the determination of entitlement to indemnification is to be made by Independent
Counsel pursuant to Section 4(b) hereof, the Independent Counsel shall be selected by the Company’s Board of Directors. Indemnitee may, within 10 days after such written notice of selection shall have been given, deliver to the
Company, as the case may be, a written objection to such selection; provided, however, that such objection may be asserted only on the ground that the Independent Counsel so selected does not meet the requirements of
“Independent Counsel” as defined in Section 11 of this Agreement, and the objection shall set forth with particularity the factual basis of such assertion. Absent a proper and timely objection, the person so selected
shall act as Independent Counsel. If a written objection is made and substantiated, the Independent Counsel selected may not serve as Independent Counsel unless and until such objection is withdrawn or a court has determined that such objection is
without merit. If, within 20 days after submission by Indemnitee of a written request for indemnification pursuant to Section 4(a) hereof, no Independent Counsel shall have been selected and not objected to, either the Company or
Indemnitee may petition the Court of Chancery of the State of Delaware or other court of competent jurisdiction for resolution of any objection that shall have been made by the Indemnitee to the Company’s selection of Independent Counsel and/or
for the appointment as Independent Counsel of a person selected by the court or by such other person as the court shall designate, and the person with respect to whom all objections are so resolved or the person so appointed shall act as Independent
Counsel under Section 4(b) hereof. The Company shall pay any and all reasonable fees and expenses of Independent Counsel incurred by such Independent Counsel in connection with acting pursuant to Section 4(b) hereof, and the
Company shall pay all reasonable fees and expenses incident to the procedures of this Section 4(c), regardless of the manner in which such Independent Counsel was selected or appointed. 
 (d) In making a determination with respect to entitlement to indemnification hereunder, the person or persons or entity making such
determination shall presume that Indemnitee is entitled to indemnification under this Agreement. Anyone seeking to overcome this presumption shall have the burden of proof and the burden of persuasion by clear and convincing evidence. Neither the
failure of the Company (including by its directors or independent legal counsel) to have made a determination prior to the commencement of any action pursuant to this Agreement that indemnification is proper in the circumstances because Indemnitee
has met the applicable standard of conduct, nor an actual determination by the Company (including by its directors or independent legal counsel) that Indemnitee has not met such applicable standard of conduct, shall be a defense to the action or
create a presumption that Indemnitee has not met the applicable standard of conduct. 
  

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 (e) Indemnitee shall be deemed to have acted in good faith if Indemnitee’s action is
based on the records or books of account of the Enterprise (including financial statements, or on information supplied to Indemnitee by the officers of the Enterprise (as hereinafter defined) in the course of their duties), the advice of legal
counsel for the Enterprise, or information or records given or reports made to the Enterprise by an independent certified public accountant or by an appraiser or other expert selected with reasonable care by the Enterprise. In addition, the
knowledge and/or actions, or failure to act, of any director, officer, agent or employee of the Enterprise shall not be imputed to Indemnitee for purposes of determining the right to indemnification under this Agreement. Whether or not the foregoing
provisions of this Section 4(e) are satisfied, it shall in any event be presumed that Indemnitee has at all times acted in good faith and in a manner he reasonably believed to be in or not opposed to the best interests of the Company.
Anyone seeking to overcome this presumption shall have the burden of proof and the burden of persuasion by clear and convincing evidence. 
 (f) If the person, persons or entity empowered or selected under Section 4 to determine whether Indemnitee is entitled to indemnification shall not have made a determination within 60 days after receipt by
the Company of the request therefor, the requisite determination of entitlement to indemnification shall be deemed to have been made and Indemnitee shall be entitled to such indemnification absent (i) a misstatement by Indemnitee of a material
fact, or an omission of a material fact necessary to make Indemnitee’s statement not materially misleading, in connection with the request for indemnification, or (ii) a prohibition of such indemnification under applicable law;
provided, however, that such 60-day period may be extended for a reasonable time, not to exceed an additional 30 days, if the person, persons or entity making such determination with respect to entitlement to indemnification in good
faith requires such additional time to obtain or evaluate documentation and/or information relating thereto; and provided, further, that the foregoing provisions of this Section 4(g) shall not apply if the determination of entitlement to
indemnification is to be made by the stockholders pursuant to Section 4(b) of this Agreement and if (A) within 15 days after receipt by the Company of the request for such determination, the Board of Directors or the Disinterested
Directors, if appropriate, resolve to submit such determination to the stockholders for their consideration at an annual meeting thereof to be held within 75 days after such receipt and such determination is made thereat, or (B) a special
meeting of stockholders is called within 15 days after such receipt for the purpose of making such determination, such meeting is held for such purpose within 60 days after having been so called and such determination is made thereat. 
 (g) Indemnitee shall cooperate with the person, persons or entity making such determination with respect to Indemnitee’s entitlement
to indemnification, including providing to such person, persons or entity upon reasonable advance request any documentation or information that is not privileged or otherwise protected from disclosure and that is reasonably available to Indemnitee
and reasonably necessary to such determination. Any Independent Counsel, member of the Board of Directors or stockholder of the Company shall act reasonably and in good faith in making a determination regarding the Indemnitee’s entitlement to
indemnification under this Agreement. Any costs or expenses (including attorneys’ fees and disbursements) incurred by Indemnitee in so cooperating with the person, persons or entity making such determination shall be borne by the Company
(irrespective of the determination as to Indemnitee’s entitlement to indemnification) and the Company hereby indemnifies and agrees to hold Indemnitee harmless therefrom. 
  

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 (h) The Company acknowledges that a settlement or other disposition short of final
judgment may be successful if it permits a party to avoid expense, delay, distraction, disruption and uncertainty. In the event that any action, claim or proceeding to which Indemnitee is a party is resolved in any manner other than by adverse
judgment against Indemnitee (including, without limitation, settlement of such action, claim or proceeding with or without payment of money or other consideration) it shall be presumed that Indemnitee has been successful on the merits or otherwise
in such action, suit or proceeding. Anyone seeking to overcome this presumption shall have the burden of proof and the burden of persuasion by clear and convincing evidence. 
 (i) The termination of any Proceeding or of any claim, issue or matter therein, by judgment, order, settlement or conviction, or upon a
plea of nolo contendere or its equivalent, shall not (except as otherwise expressly provided in this Agreement) of itself adversely affect the right of Indemnitee to indemnification or create a presumption that Indemnitee did not act in good faith
and in a manner that he reasonably believed to be in or not opposed to the best interests of the Company or, with respect to any criminal Proceeding, that Indemnitee had reasonable cause to believe that his conduct was unlawful. 
 5. Remedies of Indemnitee. 
 (a) In the event that (i) a determination is made pursuant to Section 4 of this Agreement that Indemnitee is not entitled to indemnification under this Agreement, (ii) advancement of Expenses is
not timely made pursuant to Section 3 of this Agreement, (iii) no determination of entitlement to indemnification is made pursuant to Section 4(b) of this Agreement within 90 days after receipt by the Company of the
request for indemnification, (iv) payment of indemnification is not made pursuant to this Agreement within 10 days after receipt by the Company of a written request therefor or (v) payment of indemnification is not made within 10 days
after a determination has been made that Indemnitee is entitled to indemnification or such determination is deemed to have been made pursuant to Section 4 of this Agreement, Indemnitee shall be entitled to an adjudication in an
appropriate court of the State of Delaware, or in any other court of competent jurisdiction, of Indemnitee’s entitlement to such indemnification. Indemnitee shall commence such proceeding seeking an adjudication within 180 days following the
date on which Indemnitee first has the right to commence such proceeding pursuant to this Section 5(a). The Company shall not oppose Indemnitee’s right to seek any such adjudication. 
 (b) In the event that a determination shall have been made pursuant to Section 4(b) of this Agreement that Indemnitee is not
entitled to indemnification, any judicial proceeding commenced pursuant to this Section 5 shall be conducted in all respects as a de novo trial on the merits, and Indemnitee shall not be prejudiced by reason of the adverse determination
under Section 5(b). 
 (c) If a determination shall have been made pursuant to Section 4(b) of this
Agreement that Indemnitee is entitled to indemnification, the Company shall be bound by such determination in any judicial proceeding commenced pursuant to this Section 5, absent (i) a misstatement by Indemnitee of a material fact,
or an omission of a material fact necessary to make Indemnitee’s misstatement not materially misleading in connection with the application for indemnification, or (ii) a prohibition of such indemnification under applicable law. 

 

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 (d) In the event that Indemnitee, pursuant to this Section 5, seeks a
judicial adjudication of his rights under, or to recover damages for breach of, this Agreement, or to recover under any directors’ and officers’ liability insurance policies maintained by the Company, the Company shall pay on his behalf,
in advance, any and all expenses (of the types described in the definition of Expenses in Section 11 of this Agreement) actually and reasonably incurred by him in such judicial adjudication, regardless of whether Indemnitee ultimately is
determined to be entitled to such indemnification, advancement of expenses or insurance recovery. 
 (e) The Company shall be
precluded from asserting in any judicial proceeding commenced pursuant to this Section 5 that the procedures and presumptions of this Agreement are not valid, binding and enforceable and shall stipulate in any such court that the Company
is bound by all the provisions of this Agreement. The Company shall indemnify Indemnitee against any and all Expenses and, if requested by Indemnitee, shall (within 10 days after receipt by the Company of a written request therefore) advance, to the
extent not prohibited by law, such expenses to Indemnitee as are incurred by Indemnitee in connection with any action brought by Indemnitee for indemnification or advance of Expenses from the Company under this Agreement or under any directors’
and officers’ liability insurance policies maintained by the Company, regardless of whether Indemnitee ultimately is determined to be entitled to such indemnification, advancement of Expenses or insurance recovery, as the case may be.

 (f) Notwithstanding anything in this Agreement to the contrary, no determination as to entitlement to indemnification under
this Agreement shall be required to be made prior to the final disposition of the Proceeding. 
 6. Non-Exclusivity;
Survival of Rights; Insurance; Subrogation. 
 (a) The rights of indemnification as provided by this Agreement shall not
be deemed exclusive of any other rights to which Indemnitee may at any time be entitled under applicable law, the certificate of incorporation of the Company, the bylaws of Incorporation, any agreement, a vote of stockholders, a resolution of
directors or otherwise. No amendment, alteration or repeal of this Agreement or of any provision hereof shall limit or restrict any right of Indemnitee under this Agreement in respect of any action taken or omitted by such Indemnitee in his
Corporate Status prior to such amendment, alteration or repeal. To the extent that a change in the Delaware General Corporation Law, whether by statute or judicial decision, permits greater indemnification than would be afforded currently under the
Certificate of Incorporation and this Agreement, it is the intent of the parties hereto that Indemnitee shall enjoy by this Agreement the greater benefits so afforded by such change. No right or remedy herein conferred is intended to be exclusive of
any other right or remedy, and every other right and remedy shall be cumulative and in addition to every other right and remedy given hereunder or now or hereafter existing at law or in equity or otherwise. The assertion or employment of any right
or remedy hereunder, or otherwise, shall not prevent the concurrent assertion or employment of any other right or remedy. 
  

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 (b) To the extent that the Company maintains an insurance policy or policies providing
liability insurance for directors, officers, employees, or agents or fiduciaries of the Company or of any other corporation, partnership, joint venture, trust, employee benefit plan or other enterprise that such person serves at the request of the
Company, Indemnitee shall be covered by such policy or policies in accordance with its or their terms to the maximum extent of the coverage available for any director, officer, employee, agent or fiduciary under such policy or policies. If, at the
time of the receipt of a notice of a claim pursuant to the terms hereof, the Company has director and officer liability insurance in effect, the Company shall give prompt notice of the commencement of such proceeding to the insurers in accordance
with the procedures set forth in the respective policies. The Company shall thereafter take all necessary or desirable action to cause such insurers to pay, on behalf of the Indemnitee, all amounts payable as a result of such proceeding in
accordance with the terms of such policies. 
 (c) In the event of any payment under this Agreement, the Company shall be
subrogated to the extent of such payment to all of the rights of recovery of Indemnitee, who shall execute all papers required and take all action necessary to secure such rights, including execution of such documents as are necessary to enable the
Company to bring suit to enforce such rights. 
 (d) The Company shall not be liable under this Agreement to make any payment
of amounts otherwise indemnifiable hereunder if and to the extent that Indemnitee has otherwise actually received such payment under any insurance policy, contract, agreement or otherwise. 
 (e) The Company’s obligation to indemnify or advance Expenses hereunder to Indemnitee who is or was serving at the request of the
Company as a director, officer, employee or agent of any other corporation, partnership, joint venture, trust, employee benefit plan or other enterprise shall be reduced by any amount Indemnitee has actually received as indemnification or
advancement of expenses from such other corporation, partnership, joint venture, trust, employee benefit plan or other enterprise. 
 7. Exception to Right of Indemnification. Notwithstanding any provision in this Agreement, the Company shall not be obligated under this Agreement to make any indemnity in connection with any claim made against Indemnitee:

 (a) for which payment has actually been made to or on behalf of Indemnitee under any insurance policy or other indemnity
provision, except with respect to any excess beyond the amount paid under any insurance policy or other indemnity provision; or 
 (b) for an accounting of profits made from the purchase and sale (or sale and purchase) by Indemnitee of securities of the Company within the meaning of Section 16(b) of the Securities Exchange Act of 1934, as amended, or
similar provisions of state statutory law or common law; or 
 (c) in connection with any Proceeding (or any part of any
Proceeding) initiated by Indemnitee, including any Proceeding (or any part of any Proceeding) initiated by Indemnitee against the Company or its directors, officers, employees or other indemnitees, unless (i) the Board of Directors of the
Company authorized the Proceeding (or any part of any Proceeding) prior to its initiation or (ii) the Company provides the indemnification, in its sole discretion, pursuant to the powers vested in the Company under applicable law. 

 

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 8. Duration of Agreement. All agreements and obligations of the Company contained
herein shall continue during the period Indemnitee is an officer or director of the Company (or is or was serving at the request of the Company as a director, officer, employee or agent of another corporation, partnership, joint venture, trust or
other enterprise) and shall continue thereafter so long as Indemnitee shall be subject to any Proceeding (or any proceeding commenced under Section 5 hereof) by reason of his Corporate Status, whether or not he is acting or serving in
any such capacity at the time any liability or expense is incurred for which indemnification can be provided under this Agreement. This Agreement shall be binding upon and inure to the benefit of and be enforceable by the parties hereto and their
respective successors (including any direct or indirect successor by purchase, merger, consolidation or otherwise to all or substantially all of the business or assets of the Company), assigns, spouses, heirs, executors and personal and legal
representatives. 
 9. Security. To the extent requested by Indemnitee and approved by the Board of Directors, the
Company may at any time and from time to time provide security to Indemnitee for the Company’s obligations hereunder through an irrevocable bank line of credit, funded trust or other collateral. Any such security, once provided to Indemnitee,
may not be revoked or released without the prior written consent of the Indemnitee. 
 10. Enforcement. 
 (a) The Company expressly confirms and agrees that it has entered into this Agreement and assumes the obligations imposed on it hereby in
order to induce Indemnitee to serve as an officer or director of the Company, and the Company acknowledges that Indemnitee is relying upon this Agreement in serving as an officer or director of the Company. 
 (b) This Agreement constitutes the entire agreement between the parties hereto with respect to the subject matter hereof and supersedes
all prior agreements and understandings, oral, written and implied, between the parties hereto with respect to the subject matter hereof. 
 11. Definitions. For purposes of this Agreement: 
 (a) “Corporate
Status” describes the status of a person who is or was a director, officer, employee, agent or fiduciary of the Company or of any other corporation, partnership, joint venture, trust, employee benefit plan or other enterprise that such
person is or was serving at the express written request of the Company. 
 (b) “Disinterested Director” means
a director of the Company who is not and was not a party to the Proceeding in respect of which indemnification is sought by Indemnitee. 
 (c) “Enterprise” shall mean the Company and any other corporation, partnership, joint venture, trust, employee benefit plan or other enterprise that Indemnitee is or was serving at the express written
request of the Company as a director, officer, employee, agent or fiduciary. 
  

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 (d) “Expenses” shall include all reasonable attorneys’ fees,
retainers, court costs, transcript costs, fees of experts, witness fees, travel expenses, duplicating costs, printing and binding costs, telephone charges, postage, delivery service fees and all other disbursements or expenses of the types
customarily incurred in connection with prosecuting, defending, preparing to prosecute or defend, investigating, participating, or being or preparing to be a witness in a Proceeding. Expenses also shall include Expenses incurred in connection with
any appeal resulting from any Proceeding, including without limitation the premium, security for, and other costs relating to any cost bond, supersede as bond, or other appeal bond or its equivalent. Expenses, however, shall not include amounts paid
in settlement by Indemnitee or the amount of judgments or fines against Indemnitee. 
 (e) “Independent
Counsel” means a law firm, or a member of a law firm, that is experienced in matters of corporation law and neither presently is, nor in the past five years has been, retained to represent: (i) the Company or Indemnitee in any matter
material to either such party (other than with respect to matters concerning Indemnitee under this Agreement, or of other indemnitees under similar indemnification agreements), or (ii) any other party to the Proceeding giving rise to a claim
for indemnification hereunder. Notwithstanding the foregoing, the term “Independent Counsel” shall not include any person who, under the applicable standards of professional conduct then prevailing, would have a conflict of interest
in representing either the Company or Indemnitee in an action to determine Indemnitee’s rights under this Agreement. The Company agrees to pay the reasonable fees of the Independent Counsel referred to above and to fully indemnify such counsel
against any and all Expenses, claims, liabilities and damages arising out of or relating to this Agreement or its engagement pursuant hereto. 
 (f) “Proceeding” includes any threatened, pending or completed action, suit, arbitration, alternate dispute resolution mechanism, investigation, inquiry, administrative hearing or any other actual,
threatened or completed proceeding, whether brought by or in the right of the Company or otherwise and whether civil, criminal, administrative or investigative, in which Indemnitee was, is or will be involved as a party or otherwise, by reason of
the fact that Indemnitee is or was an officer or director of the Company, by reason of any action taken by him or of any inaction on his part while acting as an officer or director of the Company, or by reason of the fact that he is or was serving
at the request of the Company as a director, officer, employee, agent or fiduciary of another corporation, partnership, joint venture, trust or other Enterprise; in each case whether or not he is acting or serving in any such capacity at the time
any liability or expense is incurred for which indemnification can be provided under this Agreement; including one pending on or before the date of this Agreement, but excluding one initiated by an Indemnitee pursuant to Section 5 of
this Agreement to enforce his rights under this Agreement. 
 12. Severability. The invalidity of unenforceability of
any provision hereof shall in no way affect the validity or enforceability of any other provision. Without limiting the generality of the foregoing, this Agreement is intended to confer upon Indemnitee indemnification rights to the fullest extent
permitted by applicable laws. In the event any provision hereof conflicts with any applicable law, such provision shall be deemed modified, consistent with the aforementioned intent, to the extent necessary to resolve such conflict. 
  

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 13. Modification and Waiver. No supplement, modification, termination or amendment
of this Agreement shall be binding unless executed in writing by both of the parties hereto. No waiver of any of the provisions of this Agreement shall be deemed or shall constitute a waiver of any other provisions hereof (whether or not similar)
nor shall such waiver constitute a continuing waiver. 
 14. Notice By Indemnitee; Right to Assume Defense. Indemnitee
agrees promptly to notify the Company in writing upon being served with or otherwise receiving any summons, citation, subpoena, complaint, indictment, information or other document relating to any Proceeding or matter which may be subject to
indemnification covered hereunder. The failure to so notify the Company shall not relieve the Company of any obligation which it may have to Indemnitee under this Agreement or otherwise unless and only to the extent that such failure or delay
materially prejudices the Company. With respect to any Proceeding of which the Company is so notified, the Company will be entitled to participate therein at its own expense and/or to assume the defense thereof at its own expense, with legal counsel
reasonably acceptable to the Indemnitee. After notice from the Company to the Indemnitee of its election so to assume such defense, the Company shall not be liable to the Indemnitee for any legal or other expenses subsequently incurred by the
Indemnitee in connection with such claim, other than as provided below in this Section 14. The Indemnitee shall have the right to employ his own counsel in connection with such Proceeding, but the fees and expenses of such counsel
incurred after notice from the Company of its assumption of the defense thereof shall be at the expense of the Indemnitee unless (i) the employment of counsel by the Indemnitee has been authorized by the Company, (ii) counsel to the
Indemnitee shall have reasonably concluded that there may be a conflict of interest or position on any significant issue between the Company and the Indemnitee in the conduct of the defense of such Proceeding or (iii) the Company shall not in
fact have promptly employed counsel to assume the defense of such Proceeding, in each of which cases the fees and expenses of counsel for the Indemnitee shall be at the expense of the Company, except as otherwise expressly provided by this
Agreement. The Company shall not be entitled, without the consent of the Indemnitee, to assume the defense of any claim brought by or in the right of the Company or as to which counsel for the Indemnitee shall have reasonably made the conclusion
provided for in clause (ii) above. The Company shall not be required to indemnify the Indemnitee under this Agreement for any amounts paid in settlement of any Proceeding effected without its written consent. The Company shall not settle any
Proceeding in any manner which would impose any penalty, limitation or liability on Indemnitee without Indemnitee’s written consent; provided, that such consent is not unreasonably withheld. 
 15. Notices. All notices and other communications given or made pursuant to this Agreement shall be in writing and shall be deemed
effectively given: (a) upon personal delivery to the party to be notified, (b) when sent by confirmed electronic mail or facsimile if sent during normal business hours of the recipient, and if not so confirmed, then on the next business
day, (c) five (5) days after having been sent by registered or certified mail, return receipt requested, postage prepaid, or (d) one (1) day after deposit with a nationally recognized overnight courier, specifying next day
delivery, with written verification of receipt. All communications shall be sent: 
  

			
	 (a)
	  	To Indemnitee at the address set forth below his signature hereto.
		
	 (b)
	  	To the Company at:
		
		  	222 Third Street
		  	Suite 2300
		  	Cambridge, MA 02142
		  	Attn: President

  

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 or to such other address as may have been furnished to Indemnitee by the Company or to the Company by
Indemnitee, as the case may be. 
 16. Counterparts. This Agreement may be executed in two or more counterparts, each
of which shall be deemed an original, but all of which together shall constitute one and the same Agreement. This Agreement may also be executed and delivered by facsimile signature and in two or more counterparts, each of which shall be deemed an
original, but all of which together shall constitute one and the same instrument. 
 17. Headings. The headings of the
paragraphs of this Agreement are inserted for convenience only and shall not be deemed to constitute part of this Agreement or to affect the construction thereof. 
 18. Governing Law and Consent to Jurisdiction. This Agreement and the legal relations among the parties shall be governed by, and
construed and enforced in accordance with, the laws of the State of Delaware, without regard to its conflict of laws rules. The Company and Indemnitee hereby irrevocably and unconditionally (i) agree that any action or proceeding arising out of
or in connection with this Agreement shall be brought only in the Chancery Court of the State of Delaware (the “Delaware Court”), and not in any other state or federal court in the United States of America or any court in any other
country, (ii) consent to submit to the exclusive jurisdiction of the Delaware Court for purposes of any action or proceeding arising out of or in connection with this Agreement, (iii) waive any objection to the laying of venue of any such
action or proceeding in the Delaware Court, and (iv) waive, and agree not to plead or to make, any claim that any such action or proceeding brought in the Delaware Court has been brought in an improper or inconvenient forum. 
 SIGNATURE PAGE TO FOLLOW 
  

 11 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement on and as of the day and year first
above written. 
  

			
	TARGANTA THERAPEUTICS CORPORATION
		
	By:	 	  
		 	Name:
		 	Title:

  

			
	INDEMNITEE
	
	  
	Name:
	
	Address:
	  
	  
	  
	  

  

 12Form of Employee Agreement Re: Non-Competition, Non-Solicitation

 Exhibit 10.18 
 AGREEMENT RE: NON-COMPETITION, NON-SOLICITATION, 
 NON-DISCLOSURE AND OWNERSHIP OF INVENTIONS

 Executed at Boston, Massachusetts, as of
                    , 20     
  

			
	BETWEEN:	  	TARGANTA THERAPEUTICS CORPORATION, a legal person incorporated under the Delaware Business Corporations Act, having its head office and principal place of business at 225 South East
Street, Suite 390, Indianapolis, Indiana, 46202 – 4002
		
		  	(hereinafter “Targanta”)
		
	AND:	  	[NAME OF EMPLOYEE], domiciled and residing at the address indicated below his/her signature
		
		  	(hereinafter the “Employee”)

 WHEREAS Targanta wishes to hire the Employee; 
 WHEREAS in his/her capacity as an employee of Targanta, the Employee hereby acknowledges that s/he may receive, initiate, contribute to, or come in contact with
Confidential Information (as defined hereunder) and that his/her employment may include inventing, discovering, initiating, or contributing to Confidential Information, as an integral part thereof; and 
 WHEREAS the parties hereto wish to establish their respective rights and obligations regarding the protection of the Confidential Information and such other
matters hereinafter set forth. 
 NOW THEREFORE, THE PARTIES HERETO AGREE AS FOLLOWS: 
  

	1.	Definitions 

 For the purposes of this
Agreement, the following definitions shall apply: 
  

	 	1.1	“Company’s Resources” means facilities, materials, or personnel owned, leased, occupied, or controlled by Targanta or its affiliates as well as the facilities,
materials, or personnel of third parties rented, leased, or otherwise hired by Targanta or its affiliates for the conduct of aspects of the business of Targanta; 

  

	 	1.2	“Competing Organization” means any person or organization engaged in or about to become engaged in any activity included in the Targanta Business;

	 	1.3	“Confidential Information” means any and all knowledge or information disclosed to or known by the Employee as a consequence of his/her employment by Targanta or
its affiliates, including without limitation all data, trade secrets, designs, inventions, processes, procedures, techniques, methodologies, formulae, compositions, compounds, product samples, ideas, know-how, production methods and processes,
genetic sequences, quality control and testing methods, specifications, software, source codes, systems data, manufacturing information and techniques, price lists and pricing information, costing information and techniques, lists of sources for
materials, equipment or apparatus used or developed by Targanta or its affiliates, supplier and customer lists and information, sales and marketing information, financial information and records, methods of doing business, management information,
budgets, manuals, materials, letters, notes, reports, business opportunities, and all other information that is identified either orally or in writing as being confidential or proprietary to Targanta or its affiliates; 

 provided however that Confidential Information shall not include any information that the Employee can prove was known to him/her prior to his/her
employment by Targanta or its affiliates and that s/he was not otherwise obliged to keep confidential, or that has passed into the public domain prior to or after its development by or for Targanta or its affiliates other than through
unauthorized acts or omissions attributable to the Employee, or that was subsequently obtained from a third party and not subject to an obligation of confidentiality in favour of the disclosing party, or that the Employee was legally
compelled to disclose. 
 Specific aspects or details of Confidential Information shall not be deemed to be within the public domain or in
the possession of the Employee merely because the Confidential Information is embraced by general disclosures in the public domain or in the possession of the Employee. In addition, any combination of Confidential Information shall not be considered
in the public domain or in the possession of the Employee merely because individual elements thereof are in the public domain or in the possession of the Employee unless the combination and its principles are in the public domain or in the
possession of the Employee; 
  

	 	1.4	“Employee” includes any person with whom Targanta or its affiliates proposes to transact business with, including, but not limited to, employees, consultants, and
advisors; 

  

	 	1.5	“Intellectual Property” means any intellectual property rights recognized in any jurisdiction, including without limitation, patents, copyrights, industrial
designs, know-how and trade secrets, that are based, in whole or in part, on any Inventions or Confidential Information, or that are created by the Employee with the use or assistance of Company Resources, or that are created by the Employee as part
of his/her employment by Targanta or its affiliates; 

  

 .2 

	 	1.6	“Inventions” means any and all inventions, discoveries, ideas, concepts, suggestions, algorithms, programs and improvements, whether patentable or not, including
but not limited to processes, methods, formulae, software, techniques as well as improvements thereof or know-how related thereto, concerning any present or prospective activities of Targanta or its affiliates with which the Employee becomes
acquainted as a result of his/her employment by Targanta or its affiliates; 

  

	 	1.7	“Period of Non-Competition and Non-Solicitation” means the period of time which is twelve (12) months from the date of the termination or expiration of the
Employee’s employment with Targanta or its affiliates, provided that if the Employee is terminated without Cause (as defined below) prior to a Change of Control (as defined below), then the relevant period of time shall be six
(6) months for purposes of Section 2.1 only. “Cause” and “Change of Control” shall have the meaning ascribed to them in the Employee’s Employment Agreement of even date herewith; 

  

	 	1.8	“Targanta Business” means the business carried on by Targanta or its affiliates consisting of (a) research and development in finding new targets for
antimicrobials, screening libraries of compounds for activity against those antimicrobial targets, and improving upon promising chemical matter with medicinal chemistry based approaches for such antimicrobial targets; (b) research and
development in finding pro-drugs of antibacterials with high affinity to bone tissue for the treatment of bone infections; and (c) clinical development and marketing of Oritavancin, an injectable glycopeptide compound, for the treatment of
infections caused by Gram positive organisms; and 

  

	 	1.9	“Territory” means any jurisdiction worldwide in which Targanta or its affiliates, at any time during the period of employment or the Period of Non-Competition and
Non-Solicitation, has filed for patent protection (regardless of the status of such filing). 

  

	2.	Non-Competition and Non-Solicitation 

 Throughout the term of his/her employment and during the Period of Non-Competition and Non-Solicitation, the Employee shall not, within the Territory, directly or indirectly, either alone or in partnership, jointly or in conjunction with
any person or persons, firm, association, partnership, syndicate, company, corporation or judicial entity whatsoever, as principal, agent, employee, officer, shareholder or investor (except as the holder of less than five percent (5%) of the
outstanding shares of a publicly traded corporation, if Targanta is so notified) or in any other manner whatsoever: 
  

	 	2.1	render services to, carry on, be engaged in, be concerned with or interested in or advise, lend money to, guarantee the debts or obligations of or permit the Employee’s name or
any part thereof to be used or employed by any Competing Organization; 

  

 .3 

	 	2.2	make use of, utilise or exploit, directly or indirectly, the Inventions for any reason whatsoever without first receiving prior written consent by Targanta; or

  

	 	2.3	solicit or assist any other person to, directly or indirectly, induce any individual who, to the Employee’s knowledge, is then employed on a full time or substantially full
time basis by Targanta or any of its affiliates to leave the employ of Targanta or any of its affiliates without the prior written consent of Targanta. 

  

	3.	Confidential Information 

 The Employee shall
not, directly or indirectly, except as expressly authorized or directed by Targanta, while employed by Targanta or any of its affiliates and indefinitely thereafter, use for his/her own benefit or that of others, copy or make notes of, disclose,
disseminate, lecture on or publish articles concerning any Confidential Information. Furthermore, the Employee shall take all reasonable precautions to preserve the confidential nature of all Confidential Information. At any time requested by
Targanta, the Employee shall deliver to Targanta, all originals and copies in his/her possession or control of all notes, reports, letters, manuals, prints, drawings, records, data, memoranda and documents of every kind and character and all other
materials relating to the Targanta Business or which contain Confidential Information, the Employee hereby acknowledging that such documentation is and remains the exclusive property of Targanta. The Employee shall have access to the documentation
surrendered to Targanta under the provisions hereof during ordinary business hours at reasonable times and frequency and upon reasonable notice in the event that reference to such documentation is required for the instituting of, or the defending
of, legal proceedings involving the Employee or is otherwise reasonably required by the Employee. 
  

	4.	Intellectual Property and Inventions 

 The
Employee hereby assigns to Targanta all of his/her right to and title and interest in all Intellectual Property, and waives all moral rights he may have therein. The Employee agrees for himself/herself and his/her heirs, personal representatives,
successors, and assigns, upon request of Targanta, at all times and without expense or compensation, to do all acts, including without limitation giving testimony in support of the Employee’s inventorship, and to execute and deliver promptly to
Targanta such papers, instruments, and documents as may from time to time be necessary or useful in Targanta’s reasonable opinion to apply for, secure, maintain, reissue, extend, or defend Targanta’s worldwide rights in Intellectual
Property, so as to secure to Targanta the full benefits of the Intellectual Property and otherwise to carry into full force and effect the text and the intent of the assignment set out above. 
 The Employee shall inform Targanta promptly and fully of all Inventions made or conceived by the Employee, whether or not during the hours of his
engagement or with the use or assistance or not of Company’s Resources, either solely or 

  

 .4 

 
jointly with others during his/her employment by Targanta or within one year after termination of such engagement by written reports, setting forth in detail
the procedures employed and the results achieved. The Employee shall submit a report promptly after completion of any studies or research projects undertaken on Targanta’s or any of its affiliate’s behalf, whether or not in the
Employee’s opinion a given project has resulted in any Invention. 
 The Employee warrants and represents to Targanta that s/he is not
subject to any agreement or university policy inconsistent with the Agreement regarding Intellectual Property set forth herein. The Employee agrees not to conduct any research or other work subject to this Agreement other than at Targanta’s and
its affiliates’ facilities and further agrees not to use any research facilities, materials, or personnel of any university or other entity not rented, leased, or otherwise hired by Targanta and its affiliates in connection with such work
without Targanta’s prior written approval. 
  

	5.	Injunctive Relief 

 The Employee acknowledges
that Targanta’s and its affiliates’ Confidential Information constitutes unique and valuable assets of Targanta, the loss or unauthorized disclosure of which would cause Targanta irreparable harm. In the event of any actual or threatened
violation by the Employee of any terms and provisions hereof, Targanta shall have the right, in addition to all other rights provided by law or by this Agreement, to obtain a provisional injunction, interlocutory injunction and permanent injunction
to prevent the Employee or persons acting on his/her behalf, from violating the provisions hereof. In such case, the Employee hereby renounces to any defence based on the availability to Targanta of other recourses, and hereby acknowledges that any
violation by him/her of the provisions hereof shall cause irreparable damage to Targanta. The Employee hereby agrees that all restrictions contained herein are reasonable and necessary for the protection of Targanta. 
  

	6.	Governing Law 

 This Agreement shall be
deemed to have been made in the Commonwealth of Massachusetts and shall be interpreted in accordance with and be governed by the laws of the Commonwealth of Massachusetts and the laws of the United States applicable therein. If any provision of this
Agreement shall be held invalid or unenforceable in any jurisdiction, such invalidity or unenforceability shall attach only to such provision in such jurisdiction and shall not in any manner affect or render invalid or unenforceable such provision
in any other jurisdiction or any other provision of this Agreement in any jurisdiction. 
  

	7.	Binding Effect 

 This Agreement shall inure
to the benefit of and be binding upon the heirs, executors, administrators and legal representatives of the Employee and the successors and permitted assigns of Targanta. Without limiting the generality of the foregoing, this Agreement and the
obligations herein contained shall survive 

  

 .5 

 
any amalgamation or corporate reorganization of Targanta such that the resulting entity shall benefit from and be entitled to enforce same against the
Employee as if it had been a party and signatory to this Agreement. 
  

	8.	Prior Agreement 

 This Agreement cancels and
replaces all previous agreements, promises, proposals, understandings and negotiations between Targanta and the Employee regarding the subject matter hereof. 
  

	9.	Amendments and Waivers 

 No amendment to this
Agreement shall be valid or binding unless made in writing and duly executed by both of the parties. No waiver of any breach or non-performance of this Agreement shall be effective or binding unless made in writing and signed by the party granting
the waiver and, unless otherwise provided in the written waiver, shall be limited to the specific breach or non-performance waived. 
  

	10.	Notices 

 Any notice required or permitted to
be given under this Agreement shall be in writing and given by hand delivery or by certified or registered mail, postage prepaid, and shall be effective on the date delivered by hand or mailed, in the case of Targanta, to its usual business address
from time to time, and in the case of the Employee, to his/her most recent home address as shown on Targanta’s records. 
  

	11.	Language 

 The Employee hereby acknowledges
that s/he has expressly required that the present Agreement and all deeds, documents or notices relating thereto be drafted in the English language. 
  

 .6 

 IN WITNESS WHEREOF Targanta and the Employee have each duly executed this Agreement as of the date set out above.

  

	
	TARGANTA THERAPEUTICS CORPORATION
	
	   
	Name:
	 Title:
  

	EMPLOYEE
	
	Print name and address below:
	
	Name:
	
	Address
	
	Address

  

 .7

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