Document:

Exhibit 10.1

 

FENNEC PHARMACEUTICALS,
INC., A DELAWARE CORPORATION

 

WESTERN
ALLIANCE BANK, an arizona corporation

 

LOAN AND
SECURITY AGREEMENT

 

     

     

    

 

This Loan
And Security Agreement is entered into as of February 1, 2019 (the “Effective Date”), by and between Western
Alliance Bank, an Arizona corporation (“Bank”) and Fennec
Pharmaceuticals, INC., a Delaware corporation (“Borrower”).

 

Recitals

 

Borrower wishes to
obtain credit from time to time from Bank, and Bank desires to extend credit to Borrower. This Agreement sets forth the terms on
which Bank will advance credit to Borrower, and Borrower will repay the amounts owing to Bank.

 

Agreement

 

The parties agree as
follows:

 

1.          Definitions
and Construction.

 

1.1           Definitions.
As used in this Agreement, the following terms shall have the following definitions:

 

“Accounts”
means all presently existing and hereafter arising accounts, contract rights, payment intangibles, and all other forms of obligations
owing to Borrower arising out of the sale or lease of goods (including, without limitation, the licensing of software and other
technology) or the rendering of services by Borrower, whether or not earned by performance, and any and all credit insurance, guaranties,
and other security therefor, as well as all merchandise returned to or reclaimed by Borrower and Borrower’s Books relating
to any of the foregoing.

 

“Affiliate”
means, with respect to any Person, any Person that owns or controls directly or indirectly such Person, any Person that controls
or is controlled by or is under common control with such Person, and each of such Person’s senior executive officers, directors,
and partners.

 

“Amortization
Date” is (i) the date that is the nineteenth month anniversary of the first day of the month immediately following the Closing
Date, if the Equity Event does not occur and (ii) the date that is the twenty-fifth month anniversary of the first day of the month
immediately following the Closing Date, if the Equity Event does occur.

 

“Anti-Terrorism
Laws” are any laws relating to terrorism or money laundering, including Executive Order No. 13224 (effective September 24,
2001), the USA PATRIOT Act, the laws comprising or implementing the Bank Secrecy Act, and the laws administered by OFAC.

 

“Approval Event”
is the receipt of the final NDA approval by Borrower from the U.S. Food and Drug Administration for Borrower’s drug candidate
currently named PEDMARK on or before September 30, 2020.

 

“Bank Expenses”
means all: reasonable costs or expenses (including reasonable attorneys’ fees and expenses) incurred in connection with the
preparation, negotiation, administration, and enforcement of the Loan Documents; reasonable Collateral audit fees; and Bank’s
reasonable attorneys’ fees and expenses incurred in amending, enforcing or defending the Loan Documents (including fees and
expenses of appeal), incurred before, during and after an Insolvency Proceeding, whether or not suit is brought.

 

“Blocked Person”
is any Person: (a) listed in the annex to, or is otherwise subject to the provisions of, Executive Order No. 13224, (b) a
Person owned or controlled by, or acting for or on behalf of, any Person that is listed in the annex to, or is otherwise subject
to the provisions of, Executive Order No. 13224, (c) a Person with which Bank is prohibited from dealing or otherwise engaging
in any transaction by any Anti-Terrorism Law, (d) a Person that commits, threatens or conspires to commit or supports “terrorism”
as defined in Executive Order No. 13224, or (e) a Person that is named a “specially designated national” or “blocked
person” on the most current list published by OFAC or other similar list.

 

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“Borrower’s
Books” means all of Borrower’s books and records including: ledgers; records concerning Borrower’s assets or
liabilities, the Collateral, business operations or financial condition; and all computer programs, or tape files, and the equipment,
containing such information.

 

“Business Day”
means any day that is not a Saturday, Sunday, or other day on which banks in the State of California are authorized or required
to close.

 

“Change in Control”
shall mean a transaction, other than an Equity Event or other bona-fide equity financing, in which any “person”
or “group” (within the meaning of Section 13(d) and 14(d)(2) of the Securities Exchange Act of 1934) becomes the “beneficial
owner” (as defined in Rule 13d-3 under the Securities Exchange Act of 1934), directly or indirectly, of a sufficient number
of shares of all classes of stock then outstanding of Borrower ordinarily entitled to vote in the election of directors, empowering
such “person” or “group” to elect a majority of the Board of Directors of Borrower, who did not have such
power before such transaction.

 

“Closing Date”
means the Funding Date of the Term Loan.

 

“Code”
means the California Uniform Commercial Code.

 

“Collateral”
means the property described on Exhibit A attached hereto.

 

“Contingent Obligation”
means, as applied to any Person, any direct or indirect liability, contingent or otherwise, of that Person with respect to (i) any
indebtedness, lease, dividend, letter of credit or other obligation of another; (ii) any obligations with respect to undrawn
letters of credit, corporate credit cards, or merchant services issued or provided for the account of that Person; and (iii) all
obligations arising under any agreement or arrangement designed to protect such Person against fluctuation in interest rates, currency
exchange rates or commodity prices; provided, however, that the term “Contingent Obligation” shall not include endorsements
for collection or deposit in the ordinary course of business. The amount of any Contingent Obligation shall be deemed to be an
amount equal to the stated or determined amount of the primary obligation in respect of which such Contingent Obligation is made
or, if not stated or determinable, the maximum reasonably anticipated liability in respect thereof as determined by Bank in good
faith; provided, however, that such amount shall not in any event exceed the maximum amount of the obligations under the guarantee
or other support arrangement.

 

“Copyrights”
means any and all copyright rights, copyright applications, copyright registrations and like protections in each work or authorship
and derivative work thereof.

 

“Credit Extension”
means any Term Loan or any other extension of credit by Bank for the benefit of Borrower hereunder.

 

“Daily Balance”
means the amount of the Obligations owed at the end of a given day.

 

“Designated Deposit
Account” means Borrower’s primary depository or operating account with Bank.

 

“Disbursement
Letter” is that certain form attached hereto as Exhibit B-1.

 

“Draw Period”
is the period commencing of the date of the occurrence of the Approval Event and ending on the earlier of (i) September 30,
2020 and (ii) the occurrence of an Event of Default; provided, however, that the Draw Period shall not commence if on the
date of the occurrence of the Approval Event an Event of Default has occurred and is continuing.

 

“Effective Date”
is defined in preamble hereof.

 

“Effective Interest
Rate” is with respect to the Term Loan, the per annum rate of interest (based on a year of three hundred sixty (360) days)
equal to the sum of (a) Index Rate on the first Business Day of the month that immediately precedes the month in which the interest
will accrue, plus (b) One percent (1.00%).

 

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“Equipment”
means all present and future machinery, equipment, tenant improvements, furniture, fixtures, vehicles, tools, parts and attachments
in which Borrower has any interest.

 

“Equity Event”
is the receipt by Parent after the Effective Date, and prior to the six month anniversary of the date of the Approval Event, of
cash proceeds of not less than Fifty Million Dollars ($50,000,000.00) from the issuance and sale by Parent of its equity securities.

 

“ERISA”
means the Employee Retirement Income Security Act of 1974, as amended, and the regulations thereunder.

 

“Event of Default”
has the meaning assigned in Article 8.

 

“Final Payment”
is a payment (in addition to and not a substitution for the regular monthly payments of principal plus accrued interest) due on
the earliest to occur of (a) the Maturity Date, or (b) the acceleration of any Term Loan, or (c) the prepayment of a Term Loan
pursuant to Section 2.2(c) or (d), equal to the original principal amount of such Term Loan multiplied by the Final Payment Percentage,
payable to Bank.

 

“Final Payment
Percentage” is three and fifty-five hundredths percent (3.55%).

 

“Funding Date”
is any date on which a Credit Extension is made to or on account of Borrower which shall be a Business Day.

 

“GAAP”
means U.S. generally accepted accounting principles as in effect from time to time.

 

“Indebtedness”
means (a) all indebtedness for borrowed money or the deferred purchase price of property or services, including without limitation
reimbursement and other obligations with respect to surety bonds and letters of credit, (b) all obligations evidenced by notes,
bonds, debentures or similar instruments, (c) all capital lease obligations and (d) all other Contingent Obligations.

 

“Index Rate”
means the Prime Rate published in the Money Rates section of the Western Edition of The Wall Street Journal.

 

“Insolvency Proceeding”
means any proceeding commenced by or against any person or entity under any provision of the United States Bankruptcy Code, as
amended, or under any other bankruptcy or insolvency law, including without limitation the Bankruptcy and Insolvency Act (Canada)
and Companies’ Creditors Arrangement Act (Canada) and similar legislation, including assignments for the benefit of
creditors, formal or informal moratoria, compositions, extension generally with its creditors, or proceedings seeking reorganization,
arrangement, winding-up, dissolution, liquidation, compromise, arrangement, adjustment, protection or other relief or a stay of
proceedings of such person’s creditors generally (or any class of creditors).

 

“Intellectual
Property” means all of Borrower’s right, title, and interest in and to the following: Copyrights, Trademarks and Patents;
all trade secrets, all design rights, claims for damages by way of past, present and future infringement of any of the rights included
above, all licenses or other rights to use any of the Copyrights, Patents or Trademarks, and all license fees and royalties arising
from such use to the extent permitted by such license or rights; all amendments, renewals and extensions of any of the Copyrights,
Trademarks or Patents; and all proceeds and products of the foregoing, including without limitation all payments under insurance
or any indemnity or warranty payable in respect of any of the foregoing.

 

“Inventory”
means all inventory in which Borrower has or acquires any interest, including work in process and finished products intended for
sale or lease or to be furnished under a contract of service, of every kind and description now or at any time hereafter owned
by or in the custody or possession, actual or constructive, of Borrower, including such inventory as is temporarily out of its
custody or possession or in transit and including any returns upon any accounts or other proceeds, including insurance proceeds,
resulting from the sale or disposition of any of the foregoing and any documents of title representing any of the above, and Borrower’s
Books relating to any of the foregoing.

 

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“Investment”
means any beneficial ownership of (including stock, partnership interest or other securities) any Person, or any loan, advance
or capital contribution to any Person.

 

“IRC” means
the Internal Revenue Code of 1986, as amended, and the regulations thereunder.

 

“Lien”
means any mortgage, lien, deed of trust, charge, pledge, security interest or other encumbrance.

 

“Loan Documents”
means, collectively, this Agreement, any note or notes (including the Secured Promissory Notes) executed by Borrower, the Parent
Loan Documents, the Warrants and any other agreement entered into in connection with this Agreement, all as amended or extended
from time to time.

 

“Material Adverse
Effect” means a material adverse effect on (i) the business operations or condition (financial or otherwise) of Borrower
and its Subsidiaries taken as a whole or the Parent and its Subsidiaries taken as whole or (ii) the ability of Borrower to repay
the Obligations or otherwise perform its obligations under the Loan Documents or (iii) the value or priority of Bank’s security
interests in the Collateral.

 

“Maturity Date”
is October 1, 2023.

 

“Monthly Cash
Burn” is for any period of determination, the sum of (i) Borrower’s average monthly net losses (calculated on a consolidated
basis with Borrower’s Subsidiaries) for the six month period then ended, (ii) the average monthly amortization and depreciation
expenses of Borrower (calculated on a consolidated basis with Borrower’s Subsidiaries) for the trailing six month period
then ended and (iii) the monthly average of the current portion of principal on interest-bearing liabilities due and payable in
the immediately succeeding three month period.

 

“Negotiable Collateral”
means all letters of credit of which Borrower is a beneficiary, notes, drafts, instruments, securities, documents of title, and
chattel paper, and Borrower’s Books relating to any of the foregoing.

 

“Obligations”
means all debt, principal, interest, the Prepayment Fee, the Final Payment, Bank Expenses and other amounts owed to Bank by Borrower
pursuant to this Agreement or any other agreement, whether absolute or contingent, due or to become due, now existing or hereafter
arising, including any interest that accrues after the commencement of an Insolvency Proceeding and including any debt, liability,
or obligation owing from Borrower to others that Bank may have obtained by assignment or otherwise.

 

“OFAC”
is the U.S. Department of Treasury Office of Foreign Assets Control.

 

“OFAC Lists”
are, collectively, the Specially Designated Nationals and Blocked Persons List maintained by OFAC pursuant to Executive Order No.
13224, 66 Fed. Reg. 49079 (Sept. 25, 2001) and/or any other list of terrorists or other restricted Persons maintained pursuant
to any of the rules and regulations of OFAC or pursuant to any other applicable Executive Orders.

 

“Parent”
is Fennec Pharmaceuticals Inc., a British Columbia (Canada) corporation, and owner of all issued and outstanding capital stock
of Borrower.

 

“Parent Guaranty”
means the guarantee of all of the Obligations by the Parent, entered into by the Parent and the Bank on the Effective Date and
in such form and substance as are agreed to by the Bank, as the same may from time to time be amended, restated, modified or otherwise
supplemented.

 

“Parent Loan
Documents” means the Parent Guaranty, the Parent Security Agreement, the Parent Share Pledge and all other documents entered
into by the Parent in connection with this Agreement.

 

“Parent Security
Agreement” means the general security agreement granted by the Parent in respect of the Parent Guaranty on the Effective
Date and in such form and substance as are agreed to by the Bank, as the same may from time to time be amended, restated, modified
or otherwise supplemented.

 

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“Parent Share
Pledge” means the share pledge agreement pursuant to which the Parent pledged all of the shares of the Borrower to the Bank
on the Effective Date and in such form and substance as are agreed to by the Bank, as the same may from time to time be amended,
restated, modified or otherwise supplemented.

 

“Patents”
means all patents, patent applications and like protections including without limitation improvements, divisions, continuations,
renewals, reissues, extensions and continuations-in-part of the same.

 

“Payment Date”
means the first (1st) calendar day of each calendar month following the Closing Date.

 

“Perfection Certificate”
has the meaning assigned in Section 3.1.

 

“Periodic Payments”
means all installments or similar recurring payments that Borrower may now or hereafter become obligated to pay to Bank pursuant
to the terms and provisions of any instrument, or agreement now or hereafter in existence between Borrower and Bank.

 

“Permitted Indebtedness”
means:

 

(a)          Indebtedness
of Borrower in favor of Bank arising under this Agreement or any other Loan Document;

 

(b)          Indebtedness
existing on the Effective Date and disclosed in the Perfection Certificate on the Effective Date;

 

(c)          Indebtedness
secured by a lien described in clause (e) of the defined term “Permitted Liens,” provided (i) such Indebtedness
does not exceed the lesser of the cost or fair market value of the equipment financed with such Indebtedness and (ii) such
Indebtedness does not exceed $250,000 in the aggregate at any given time;

 

(d)          Subordinated
Debt;

 

(e)          Unsecured
Indebtedness to trade creditors incurred in the ordinary course of business;

 

(f)           Indebtedness
incurred as a result of endorsing negotiable instruments received in the ordinary course of business; and

 

(g)          extensions,
refinancings, modifications, amendments and restatements of any items of Permitted Indebtedness (a) through (f) above, provided
that the principal amount thereof is not increased or the terms thereof are not modified to impose more burdensome terms upon Borrower
or its Subsidiary, as the case may be.

 

“Permitted Investment”
means:

 

(a)          Investments
existing on the Effective Date disclosed in the Perfection Certificate;

 

(b)          (i) marketable
direct obligations issued or unconditionally guaranteed by the United States of America or any agency or any State thereof maturing
within one (1) year from the date of acquisition thereof, (ii) commercial paper maturing no more than one (1) year from the
date of creation thereof and currently having rating of at least A-2 or P-2 from either Standard & Poor’s Corporation
or Moody’s Investors Service, (iii) certificates of deposit maturing no more than one (1) year from the date of investment
therein issued by Bank and (iv) Bank’s money market accounts;

 

(c)          Investments
consisting of the endorsement of negotiable instruments for deposit or collection or similar transactions in the ordinary course
of Borrower;

 

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(d)         Investments
consisting of deposit accounts in which Bank has a perfected security interest;

 

(e)          Investments
consisting of (i) travel advances and employee relocation loans and other employee loans and advances in the ordinary course of
business, and (ii) loans to employees, officers or directors relating to the purchase of equity securities of Borrower or its Subsidiaries
pursuant to employee stock purchase plans or agreements approved by Borrower’s Board of Directors; not to exceed in the aggregate
for (i) and (ii), Five Hundred Thousand Dollars ($500,000) in any fiscal year;

 

(f)          Investments
(including debt obligations) received in connection with the bankruptcy or reorganization of customers or suppliers and in settlement
of delinquent obligations of, and other disputes with, customers or suppliers arising in the ordinary course of business;

 

(g)          Investments
consisting of notes receivable of, or prepaid royalties and other credit extensions, to customers and suppliers who are not Affiliates,
in the ordinary course of business; provided that this paragraph (h) shall not apply to Investments of Borrower in any Subsidiary;
and

 

(h)          non-cash
Investments in joint ventures or strategic alliances in the ordinary course of Borrower’s business consisting of Permitted
Licenses, the development of technology or the providing of technical support.

 

“Permitted Liens”
means the following:

 

(a)          Any
Liens existing on the Effective Date and disclosed in the Perfection Certificate on the Effective Date or arising under this Agreement
or the other Loan Documents;

 

(b)          Liens
for taxes, fees, assessments or other governmental charges or levies, either not delinquent or being contested in good faith by
appropriate proceedings, provided the same have no priority over any of Bank’s security interests;

 

(c)           Liens
(i) upon or in any equipment which was not financed by Bank acquired or held by Borrower or any of its Subsidiaries to secure
the purchase price of such equipment or indebtedness incurred solely for the purpose of financing the acquisition of such equipment,
or (ii) existing on such equipment at the time of its acquisition, provided that the Lien is confined solely to the property
so acquired and improvements thereon, and the proceeds of such equipment;

 

(d)          Liens
of carriers, warehousemen, suppliers, or other Persons that are possessory in nature arising in the ordinary course of business
so long as such Liens attach only to Inventory, securing liabilities in the aggregate amount not to exceed One Hundred Thousand
Dollars ($100,000.00) and which are not delinquent or remain payable without penalty or which are being contested in good faith
and by appropriate proceedings which proceedings have the effect of preventing the forfeiture or sale of the property subject thereto;

 

(e)           Liens
to secure payment of workers’ compensation, employment insurance, old-age pensions, social security and other like obligations
incurred in the ordinary course of business (other than Liens imposed by ERISA);

 

(f)           leases
or subleases of real property granted in the ordinary course of Borrower’s business (or, if referring to another Person,
in the ordinary course of such Person’s business), and leases, subleases, non-exclusive licenses or sublicenses of personal
property and granted in the ordinary course of Borrower’s business (or, if referring to another Person, in the ordinary course
of such Person’s business), if the leases, subleases, licenses and sublicenses do not prohibit granting Bank a security interest
therein;

 

(g)          Liens
arising from judgments, decrees or attachments in circumstances not constituting an Event of Default under Section 8.4 or
8.7;

 

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(h)          Liens
in favor of other financial institutions arising in connection with Borrower’s deposit and/or securities accounts held at
such institutions, provided that Borrower is permitted under the terms of this Agreement to maintain such accounts and Bank has
a perfected first priority security interest in the amounts held in such deposit and/or securities accounts;

 

(i)           Liens
consisting of Permitted Licenses; and

 

(j)           Liens
incurred in connection with the extension, renewal or refinancing of the indebtedness secured by Liens of the type described in
clauses (a) through (i) above, provided that any extension, renewal or replacement Lien shall be limited to the property encumbered
by the existing Lien and the principal amount of the indebtedness being extended, renewed or refinanced does not increase.

 

“Permitted Licenses”
are (A) licenses of over-the-counter software that is commercially available to the public, (B) non-exclusive license for the use
of the Intellectual Property of Borrower or any of its Subsidiaries entered into in the ordinary course of business, provided,
that, with respect to each such license described in clause (B) (i) the license constitutes an arms-length transaction, the terms
of which, on their face, do not provide for a sale or assignment of any Intellectual Property and do not restrict the ability of
Borrower or any of its Subsidiaries, as applicable, to pledge, grant a security interest in or lien on, or assign or otherwise
Transfer any Intellectual Property; (ii) Borrower delivers to Bank copies of the final executed licensing documents in connection
with the non-exclusive license promptly, and in any event within ten (10) days of the consummation thereof, and (iii) all upfront
payments, royalties, milestone payments or other proceeds arising from the licensing agreement that are payable to Borrower or
any of its Subsidiaries are paid to a deposit account maintained at the Bank, and (C) exclusive licenses for the use of the Intellectual
Property of Borrower or any of its Subsidiaries entered into in the ordinary course of business, provided, that, with respect to
each such license described in clause (C) (i) no Event of Default has occurred or is continuing at the time of such license; (ii)
the license constitutes an arms-length transaction, the terms of which, on their face, do not provide for a sale or assignment
of any Intellectual Property and do not restrict the ability of Borrower or any of its Subsidiaries, as applicable, to pledge,
grant a security interest in or lien on, or assign or otherwise Transfer any Intellectual Property; (iii) (x) Borrower delivers
copies of the final executed licensing documents in connection with the exclusive license promptly, and in any event within ten
(10) days of the consummation thereof, and (y) any such license could not result in a legal transfer of title of the licensed property
but may be exclusive in respects other than territory and may be exclusive as to territory only as to discrete geographical areas
outside the United States and (iv) all upfront payments, royalties, milestone payments or other proceeds arising from the licensing
agreement that are payable to Borrower or any of its Subsidiaries are paid to a deposit account maintained at the Bank.

 

“Person”
means any individual, sole proprietorship, partnership, limited liability company, joint venture, trust, unincorporated organization,
association, corporation, institution, public benefit corporation, firm, joint stock company, estate, entity or governmental agency.

 

“PPSA”
means the Personal Property Security Act (British Columbia) “PPSA” or any successor personal property security
statute or similar legislation of any other Canadian province or territorial jurisdiction, including without limitation, the Civil
Code of Quebec, the laws of which are required by such legislation to be applied in connection with the issue, perfection, enforcement,
opposability, priority, validity or effect of security interests.

 

“Prepayment Fee”
is, with respect to any Term Loan subject to prepayment prior to the Maturity Date, whether by mandatory or voluntary prepayment,
acceleration or otherwise, an additional fee payable to Bank in amount equal to percent (1.0%) of the principal amount of the Term
Loan prepaid.

 

“Responsible
Officer” means each of the Chief Executive Officer, the Chief Operating Officer, the Chief Financial Officer and the Controller
of Borrower.

 

“Schedule”
means the schedule of exceptions attached hereto and approved by Bank, if any.

 

“Secured Promissory
Note” is defined in Section 2.7.

 

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“Secured Promissory
Note Record” is a record maintained by the Bank with respect to the outstanding Obligations owed by Borrower to the Bank
and credits made thereto.

 

“Subordinated
Debt” means any debt incurred by Borrower that is subordinated to the debt owing by Borrower to Bank on terms acceptable
to Bank (and identified as being such by Borrower and Bank).

 

“Subsidiary”
means any corporation, company or partnership in which (i) any general partnership interest or (ii) more than 50% of
the stock or other units of ownership which by the terms thereof has the ordinary voting power to elect the Board of Directors,
managers or trustees of the entity, at the time as of which any determination is being made, is owned by Borrower, either directly
or through an Affiliate.

 

“Term Loan”
is defined in Section 2.2(a) hereof.

 

“Total Liabilities”
means at any date as of which the amount thereof shall be determined, all obligations that should, in accordance with GAAP be classified
as liabilities on the consolidated balance sheet of Borrower, including in any event all Indebtedness.

 

“Trademarks”
means any trademark and servicemark rights, whether registered or not, applications to register and registrations of the same and
like protections, and the entire goodwill of the business of Borrower connected with and symbolized by such trademarks.

 

“Warrants”
are those certain Warrants to purchase Parent’s capital stock from and after the Effective Date until expiry thereof, issued
by Borrower in favor of the Bank on the Effective Date.

 

1.2           Accounting
Terms. All accounting terms not specifically defined herein shall be construed in accordance with GAAP and all calculations
made hereunder shall be made in accordance with GAAP. When used herein, the terms “financial statements” shall include
the notes and schedules thereto.

 

2.          Loan
and Terms Of Payment.

 

2.1           Credit
Extensions.

 

Borrower promises to
pay to the order of Bank, in lawful money of the United States of America, the aggregate unpaid principal amount of all Credit
Extensions made by Bank to Borrower hereunder. Borrower shall also pay interest on the unpaid principal amount of such Credit Extensions
at rates in accordance with the terms hereof.

 

2.2           Term
Loan.

 

(a)          Availability.
Subject to the terms and conditions of this Agreement, during the Draw Period, Bank shall make a term loan to Borrower in the amount
of Twelve Million Five Hundred Thousand Dollars ($12,500,000) (such term loan is hereinafter referred to as “Term Loan”).

 

(b)          Repayment.
Borrower shall make monthly payments of interest only commencing on the first (1st) Payment Date following the Funding Date of
each Term Loan, and continuing on the Payment Date of each successive month thereafter through and including the Payment Date immediately
preceding the Amortization Date of such Term Loan. Borrower agrees to pay, on the Funding Date of each Term Loan, any initial partial
monthly interest payment otherwise due for the period between the Funding Date of such Term Loan and the first Payment Date thereof.
Commencing on the Amortization Date for the Term Loan, and continuing on the Payment Date of each month thereafter, Borrower shall
make equal monthly payments of principal, together with applicable interest, in arrears, as calculated by Bank (which calculations
shall be deemed correct absent manifest error) based upon: (1) the amount of the Term Loan, (2) the effective rate of interest,
as determined in Section 2.4(a), and (3) a repayment schedule as determined by the Bank based on the Maturity Date and the Amortization
Date (which determination shall be deemed correct absent manifest error). All unpaid principal and accrued and unpaid interest
is due and payable in full on the Maturity Date with respect to the Term Loan. The Term Loan may only be prepaid in accordance
with Sections 2.2(c) and 2.2(d).

 

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(c)          Mandatory
Prepayments. If the Term Loan is accelerated following the occurrence of an Event of Default, Borrower shall immediately pay
to Bank, an amount equal to the sum of: (i) all outstanding principal of the Term Loan plus accrued and unpaid interest thereon
through the prepayment date, (ii) the Final Payment, (iii) the Prepayment Fee, plus (iv) all other Obligations that are
due and payable, including Bank’s Expenses and interest at the Default Rate with respect to any past due amounts. Notwithstanding
(but without duplication with) the foregoing, on the Maturity Date, if the Final Payment had not previously been paid in full in
connection with the prepayment of the Term Loan in full, Borrower shall pay Bank the Final Payment in respect of the Term Loan(s).

 

(d)          Permitted
Prepayment of Term Loan. Borrower shall have the option to prepay all, but not less than all, of the Term Loan advanced by
Bank under this Agreement, provided Borrower (i) provides written notice to Bank of its election to prepay the Term Loan at
least thirty (30) days prior to such prepayment, and (ii) pays to the Bank on the date of such prepayment an amount equal
to the sum of (A) all outstanding principal of the Term Loan plus accrued and unpaid interest thereon through the prepayment
date, (B) the Final Payment, (C) the Prepayment Fee, plus (D) all other Obligations that are due and payable, including Bank’s
Expenses and interest at the Default Rate with respect to any past due amounts.

 

2.3           Interest
Rate, Payments, and Calculations.

 

(a)          Interest
Rate. Except as set forth in Section 2.4(b) below, the Term Loan shall bear interest, on the outstanding Daily Balance thereof,
at a floating per annum rate equal to the Effective Interest Rate.

 

(b)          Late
Fee; Default Rate. If any payment is not made within ten (10) days after the date such payment is due, Borrower shall pay Bank
a late fee equal to the lesser of (i) five percent (5%) of the amount of such unpaid amount or (ii) the maximum amount
permitted to be charged under applicable law, not in any case to be less than $25.00. All Obligations shall bear interest, from
and after the occurrence and during the continuance of an Event of Default, at a rate equal to five (5) percentage points above
the interest rate applicable immediately prior to the occurrence of the Event of Default.

 

(c)          Payments.
Interest hereunder shall be due and payable on the first calendar day of each month during the term hereof. Bank shall, at its
option, charge such interest, all Bank Expenses, and all Periodic Payments against any of Borrower’s deposit accounts (including
but not limited to the Designated Deposit Account), in which case those amounts shall thereafter accrue interest at the rate then
applicable hereunder. Any interest not paid when due shall be compounded by becoming a part of the Obligations, and such interest
shall thereafter accrue interest at the rate then applicable hereunder. All payments shall be free and clear of any taxes, withholdings,
duties, impositions or other charges, to the end that Bank will receive the entire amount of any Obligations payable hereunder,
regardless of source of payment.

 

(d)          Computation.
In the event the Index Rate is changed from time to time hereafter, the applicable rate of interest hereunder shall be increased
or decreased, as set forth in the definition of “Effective Interest Rate.” All interest chargeable under the Loan Documents
shall be computed on the basis of a three hundred sixty (360) day year for the actual number of days elapsed. For the purposes
of the Interest Act (Canada) and disclosure under such statute: (i) whenever any interest or fee under this Agreement is
calculated on the basis of a period of time other than a calendar year, such rate used in such calculation, when expressed as an
annual rate, is equivalent to (x) such rate, multiplied by (y) the actual number of days in the calendar year in which the period
for which such interest or fee is calculated ends, and divided by (z) the number of days in such period of time; (ii) the principle
of deemed reinvestment of interest shall not apply to any interest calculation under this Agreement; and (iii) the rates of interest
stipulated in this Agreement are intended to be nominal rates and not effective rates or yields.

 

    	9

     

    

 

2.4           Crediting
Payments. Prior to the occurrence of an Event of Default, Bank shall credit a wire transfer of funds, check or other item of
payment to such deposit account or Obligation as Borrower specifies. After the occurrence of an Event of Default, the receipt by
Bank of any wire transfer of funds, check, or other item of payment shall be immediately applied to conditionally reduce Obligations,
but shall not be considered a payment on account unless such payment is of immediately available federal funds or unless and until
such check or other item of payment is honored when presented for payment. Notwithstanding anything to the contrary contained herein,
any wire transfer or payment received by Bank after 12:00 noon Pacific time shall be deemed to have been received by Bank
as of the opening of business on the immediately following Business Day. Whenever any payment to Bank under the Loan Documents
would otherwise be due (except by reason of acceleration) on a date that is not a Business Day, such payment shall instead be due
on the next Business Day, and additional fees or interest, as the case may be, shall accrue and be payable for the period of such
extension.

 

2.5           Fees.
Borrower shall pay to Bank the following:

 

(a)          Good
Faith Deposit. An amount of Fifty Two Thousand Five Hundred Dollars ($52,500.00) as good faith deposit from Borrower (which
Bank acknowledges was received on or about December 21, 2018) and shall be applied towards the Bank Expenses due under Section
2.5(d) on the Effective Date, and the balance, if any, shall be promptly returned by the Bank to Borrower on the Effective Date.

 

(b)          Final
Payment. The Final Payment, when due hereunder;

 

(c)          Prepayment
Fee. The Prepayment Fee, when due hereunder; and

 

(d)          Bank
Expenses. On the Effective Date, all Bank Expenses incurred through such date, including reasonable attorneys’ fees and
expenses and, after the Effective Date, all Bank Expenses, including reasonable attorneys’ fees and expenses, as and when
they are incurred by Bank.

 

2.6           Term.
This Agreement shall become effective on the date hereof and, subject to Section 13.7, shall continue in full force and effect
for so long as any Obligations remain outstanding or Bank has any obligation to make Credit Extensions under this Agreement. Notwithstanding
the foregoing, Bank shall have the right to terminate its obligation to make Credit Extensions under this Agreement immediately
and without notice upon the occurrence and during the continuance of an Event of Default. Notwithstanding termination, Bank’s
Lien on the Collateral shall remain in effect for so long as any Obligations are outstanding.

 

2.7           Secured
Promissory Notes. The Term Loan shall be evidenced by a Secured Promissory Note or Notes in the form attached as Exhibit D
hereto (each a “Secured Promissory Note”), and shall be repayable as set forth in this Agreement. Borrower irrevocably
authorizes the Bank to make or cause to be made, on or about the Funding Date of any Term Loan or at the time of receipt of any
payment of principal on such Secured Promissory Note, an appropriate notation on such Secured Promissory Note Record reflecting
the making of such Term Loan or (as the case may be) the receipt of such payment. The outstanding amount of each Term Loan set
forth on such Secured Promissory Note Record shall be prima facie evidence of the principal amount thereof owing and unpaid to
the Bank, but the failure to record, or any error in so recording, any such amount on such Secured Promissory Note Record shall
not limit or otherwise affect the obligations of Borrower under any Secured Promissory Note or any other Loan Document to make
payments of principal of or interest on any Secured Promissory Note when due. Upon receipt of an affidavit of an officer of the
Bank as to the loss, theft, destruction, or mutilation of any of its Secured Promissory Note, Borrower shall issue, in lieu
thereof, a replacement Secured Promissory Note in the same principal amount thereof and of like tenor.

 

3.          Conditions
of Loans.

 

3.1           Conditions
Precedent to Initial Credit Extension. The obligation of Bank to make the initial Credit Extension is subject to the condition
precedent that Bank shall have received, in form and substance satisfactory to Bank, the following:

 

(a)          this
Agreement, duly executed by Borrower on the Effective Date and delivered on the Effective Date;

 

    	10

     

    

 

(b)          a
certificate of the Secretary of Borrower with respect to incumbency and resolutions authorizing the execution and delivery of this
Agreement, dated as of the Effective Date and delivered on the Effective Date;

 

(c)          a
certificate of the Secretary of Borrower with respect to incumbency and resolutions authorizing the execution and delivery of this
Agreement, dated as of the Closing Date and delivered on the Closing Date;

 

(d)          UCC
National Form Financing Statement to be filed on the Effective Date;

 

(e)          a
duly executed Warrant to purchase stock of Parent in such form and substance as is agreed to by the parties, dated as of the Effective
Date and delivered on the Effective Date for the purposes of the Term Loan;

 

(f)           a
duly executed account control agreement with respect to the account maintained by the Parent with Royal Bank of Canada on the Effective
Date, which control agreement must be in such form and substance as are reasonably satisfactory to the Bank;

 

(g)          duly
executed original Secured Promissory Notes in favor of the Bank, dated as of the Closing Date and delivered on the Closing Date;

 

(h)          agreement
to provide insurance, dated as of the Effective Date and delivered on the Effective Date;

 

(i)           payment
of the fees and Bank Expenses then due specified in Section 2.5 hereof;

 

(j)          current
consolidated financial statements of the Parent delivered on or prior to the Effective Date;

 

(k)          evidence
of closure of Borrower’s and Parent’s accounts maintained with Banc of California and transfer of all funds therein
to accounts maintained with the Bank, on the Effective Date;

 

(l)           completed
perfection certificate of Borrower (the “Perfection Certificate”), dated as of the Effective Date and delivered on
the Effective Date;

 

(m)         a
landlord’s consent for each of Borrower and Parent’s leased locations delivered on or prior to the Closing Date;

 

(n)          a
bailee waiver for each location where Borrower maintains Collateral having a book value in excess of Two Hundred and Fifty Thousand
Dollars ($250,000), delivered on or prior to the Closing Date;

 

(o)          a
Disbursement Letter in the form of Exhibit B-1 attached hereto, delivered on the Closing Date and dated as of the Closing
Date;

 

(p)          a
Loan Payment/Advance Request Form in the form of Exhibit B-2 attached hereto, dated as of the Closing Date and delivered
on the Closing Date;

 

(q)          the
Parent Loan Documents on the Effective Date and any and all documents and deliverables contemplated therein on the applicable dates
as set forth therein;

 

(r)          a
certificate of an officer of the Parent with respect to incumbency and resolutions authorizing the execution and delivery of this
the Parent Loan Documents and Warrants, dated as of the Closing Date and delivered on the Closing Date;

 

    	11

     

    

 

(s)          a
Certificate of Good Standing of the Parent dated on or about the Effective Date;

 

(t)           receipt
of a filed copy, which shall be filed by the Bank, acknowledged by the appropriate filing office, of an all asset PPSA Financing
Statement, naming the Parent as “Debtor” and the Bank as “Secured Party”;

 

(u)          account
control agreements in favor of the Bank, in such form and substance as are reasonably satisfactory to the Bank and dated and delivered
on or prior to the Effective Date, with respect to the accounts maintained by Borrower and Parent at the PNC Bank and at the Royal
Bank of Canada;

 

(v)          evidence
on the Closing Date that Borrower has sufficient cash reserves (including the proceeds of the Term Loan) in accounts maintained
with the Bank to meet all of its projected expenses in accordance with its then applicable annual operating budget and financial
projections delivered and accepted by Bank in its sole discretion (including, but not limited to, interest expenses and any applicable
principal repayment expenses) for the then immediately following twelve-month period; and

 

(w)         such
other documents, and completion of such other matters, as Bank may reasonably deem necessary or appropriate.

 

3.2           Conditions
Precedent to all Credit Extensions. The obligation of Bank to make each Credit Extension, including the initial Credit Extension,
is further subject to the representations and warranties contained in Section 5 shall be true and correct in all material
respects on and as of the effective date of each Credit Extension as though made at and as of each such date, and no Event of Default
shall have occurred and be continuing, or would exist after giving effect to such Credit Extension. The making of each Credit Extension
shall be deemed to be a representation and warranty by Borrower on the date of such Credit Extension as to the accuracy of the
facts referred to in this Section 3.2. Furthermore, the making of each Credit Extension shall be subject to the delivery by
Borrower to the Bank, to the extent not delivered at the Closing, of duly executed original Secured Promissory Notes and Warrants,
in number, form and content acceptable to the Bank, with respect to such Credit Extension made by the Bank after the Closing Date.

 

3.3           Procedures
for Borrowing. Whenever Borrower desires a Term Loan, Borrower will notify Bank no later than 3:00 p.m. Pacific time,
three (3) Business Days prior to the date the Term Loan is to be made. Each such notification shall be made (i) by telephone or
in-person followed by written confirmation from Borrower within twenty four (24) hours, (ii) by electronic mail or facsimile
transmission, or (iii) by delivering to Bank a Loan Payment/Advance Request Form in substantially the form of Exhibit B-2
hereto. Bank shall be entitled to rely on any notice given by a person who Bank reasonably believes to be a Responsible Officer
or a designee thereof, and Borrower shall indemnify and hold Bank harmless for any damages or loss suffered by Bank as a result
of such reliance. Bank will credit the amount of Term Loan made under this Section 3.3 to Borrower’s deposit account.

 

4.          Creation
of Security Interest.

 

4.1           Grant
of Security Interest. Borrower hereby grants and pledges to Bank a continuing security interest in all presently existing and
hereafter acquired or arising Collateral in order to secure prompt repayment of any and all Obligations and in order to secure
prompt performance by Borrower of each of its covenants and duties under the Loan Documents. Except as set forth in the Perfection
Certificate, such security interest constitutes a valid, first priority security interest in the presently existing Collateral,
and will constitute a valid, first priority security interest in Collateral acquired after the date hereof.

 

4.2           Delivery
of Additional Documentation Required. Borrower shall from time to time execute and deliver to Bank, at the request of Bank,
all Negotiable Collateral, all financing statements and other documents that Bank may reasonably request, in form satisfactory
to Bank, to perfect and continue the perfection of Bank’s security interests in the Collateral and in order to fully consummate
all of the transactions contemplated under the Loan Documents. Borrower from time to time may deposit with Bank specific time deposit
accounts to secure specific Obligations. Borrower authorizes Bank to hold such balances in pledge and to decline to honor any drafts
thereon or any request by Borrower or any other Person to pay or otherwise transfer any part of such balances for so long as the
Obligations are outstanding.

 

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4.3           Right
to Inspect. Bank (through any of its officers, employees, or agents) shall have the right, upon reasonable prior notice, from
time to time during Borrower’s usual business hours but no more than twice a year (unless an Event of Default has occurred
and is continuing), to inspect Borrower’s Books and to make copies thereof and to check, test, and appraise the Collateral
in order to verify Borrower’s financial condition or the amount, condition of, or any other matter relating to, the Collateral.

 

5.          Representations
and Warranties.

 

Borrower hereby represents
and warrants as follows:

 

5.1           Due
Organization and Qualification. Borrower and each Subsidiary is a corporation duly existing under the laws of its state of
incorporation and qualified and licensed to do business in any state in which the conduct of its business or its ownership of property
requires that it be so qualified.

 

5.2           Due
Authorization; No Conflict. The execution, delivery, and performance of the Loan Documents are within Borrower’s powers,
have been duly authorized, and are not in conflict with nor constitute a breach of any provision contained in Borrower’s
Articles of Incorporation or Bylaws, nor will they constitute an event of default under any material agreement to which Borrower
is a party or by which Borrower is bound. Borrower is not in default under any material agreement to which it is a party or by
which it is bound.

 

5.3           No
Prior Encumbrances. Borrower has good and marketable title to its property, free and clear of Liens, except for Permitted Liens.

 

5.4           Merchantable
Inventory. All Inventory is in all material respects of good and marketable quality, free from all material defects, except
for Inventory for which adequate reserves have been made.

 

5.5           Intellectual
Property. Borrower is the sole owner of the Intellectual Property, except for Permitted Licenses or as set forth on the Perfection
Certificate on the Effective Date. Each of the Patents is valid and enforceable, and no part of the Intellectual Property has been
judged invalid or unenforceable, in whole or in part, and no claim has been made that any part of the Intellectual Property violates
the rights of any third party. Except as set forth in the Perfection Certificate, Borrower’s rights as a licensee of intellectual
property do not give rise to more than five percent (5.00%) of its gross revenue in any given month, including without limitation
revenue derived from the sale, licensing, rendering or disposition of any product or service. Except as set forth in the Perfection
Certificate, Borrower is not a party to, or bound by, any agreement that restricts the grant by Borrower of a security interest
in Borrower’s rights under such agreement.

 

5.6           Name;
Location of Chief Executive Office. Except as disclosed in the Perfection Certificate, Borrower has not done business under
any name other than that specified on the signature page hereof. The chief executive office of Borrower is located at the address
indicated in Section 10 hereof. All Borrower’s Inventory and Equipment is located only at the location set forth in
Section 10 hereof.

 

5.7           Litigation.
Except as set forth in the Perfection Certificate, there are no actions or proceedings pending by or against Borrower or any Subsidiary
before any court or administrative agency in which an adverse decision could have a Material Adverse Effect, or a material adverse
effect on Borrower’s interest or Bank’s security interest in the Collateral.

 

5.8           No
Material Adverse Change in Financial Statements. All consolidated and consolidating financial statements related to Borrower
and any Subsidiary that Bank has received from Borrower fairly present in all material respects Borrower’s financial condition
as of the date thereof and Borrower’s consolidated and consolidating results of operations for the period then ended. There
has not been a material adverse change in the consolidated or the consolidating financial condition of Borrower since the date
of the most recent of such financial statements submitted to Bank.

 

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5.9           Solvency,
Payment of Debts. Borrower is solvent and able to pay its debts (including trade debts) as they mature.

 

5.10         Regulatory
Compliance. Borrower and each Subsidiary have met the minimum funding requirements of ERISA with respect to any employee benefit
plans subject to ERISA, and no event has occurred resulting from Borrower’s failure to comply with ERISA that could result
in Borrower’s incurring any material liability. Borrower is not an “investment company” or a company “controlled”
by an “investment company” within the meaning of the Investment Company Act of 1940. Borrower is not engaged principally,
or as one of the important activities, in the business of extending credit for the purpose of purchasing or carrying margin stock
(within the meaning of Regulations T and U of the Board of Governors of the Federal Reserve System). Borrower has complied
with all the provisions of the Federal Fair Labor Standards Act. Borrower has not violated any statutes, laws, ordinances or rules
applicable to it, violation of which has or could reasonably be expected to have a Material Adverse Effect.

 

None of the Parent,
the Borrower, any of its Subsidiaries, or any of Borrower’s or its Subsidiaries’ Affiliates or any of their respective
agents acting or benefiting in any capacity in connection with the transactions contemplated by this Agreement is (i) in violation
of any Anti-Terrorism Law, (ii) engaging in or conspiring to engage in any transaction that evades or avoids, or has the purpose
of evading or avoiding or attempts to violate, any of the prohibitions set forth in any Anti-Terrorism Law, or (iii) is a Blocked
Person. None of the Parent, the Borrower, any of its Subsidiaries, or to the knowledge of Borrower and any of their Affiliates
or agents, acting or benefiting in any capacity in connection with the transactions contemplated by this Agreement, (x) conducts
any business or engages in making or receiving any contribution of funds, goods or services to or for the benefit of any Blocked
Person, or (y) deals in, or otherwise engages in any transaction relating to, any property or interest in property blocked pursuant
to Executive Order No. 13224, any similar executive order or other Anti-Terrorism Law.

 

5.11         Environmental
Condition. Except as disclosed in the Perfection Certificate, none of Borrower’s or any Subsidiary’s properties
or assets has ever been used by Borrower or any Subsidiary or, to the best of Borrower’s knowledge, by previous owners or
operators, in the disposal of, or to produce, store, handle, treat, release, or transport, any hazardous waste or hazardous substance
other than in accordance with applicable law; to the best of Borrower’s knowledge, none of Borrower’s properties or
assets has ever been designated or identified in any manner pursuant to any environmental protection statute as a hazardous waste
or hazardous substance disposal site, or a candidate for closure pursuant to any environmental protection statute; no lien arising
under any environmental protection statute has attached to any revenues or to any real or personal property owned by Borrower or
any Subsidiary; and neither Borrower nor any Subsidiary has received a summons, citation, notice, or directive from the Environmental
Protection Agency or any other federal, state or other governmental agency concerning any action or omission by Borrower or any
Subsidiary resulting in the releasing, or otherwise disposing of hazardous waste or hazardous substances into the environment.

 

5.12         Taxes.
Borrower and each Subsidiary have filed or caused to be filed all tax returns required to be filed, and have paid, or have made
adequate provision for the payment of, all taxes reflected therein.

 

5.13         Subsidiaries.
Borrower does not own any stock, partnership interest or other equity securities of any Person, except for Permitted Investments.

 

5.14         Government
Consents. Borrower and each Subsidiary have obtained all material consents, approvals and authorizations of, made all declarations
or filings with, and given all notices to, all governmental authorities that are necessary for the continued operation of Borrower’s
business as currently conducted.

 

5.15         Accounts.
Other than as set forth on the Perfection Certificate, none of Borrower’s nor any Subsidiary’s property is maintained
or invested with a Person other than Bank.

 

    	14

     

    

 

5.16         Use
of Proceeds. Borrower shall use the proceeds of the Term Loan solely as working capital and to fund its general business requirements
in accordance with the provisions of this Agreement, and not for personal, family, household or agricultural purposes.

 

5.17         Full
Disclosure. No representation, warranty or other statement made by Borrower in any certificate or written statement furnished
to Bank contains any untrue statement of a material fact or omits to state a material fact necessary in order to make the statements
contained in such certificates or statements not misleading.

 

6.          Affirmative
Covenants.

 

Commencing on the Effective
Date, Borrower shall do all of the following:

 

6.1           Good
Standing. Borrower shall maintain its and each of its Subsidiaries’ corporate existence and good standing in its jurisdiction
of incorporation and maintain qualification in each jurisdiction in which it is required under applicable law. Borrower shall maintain,
and shall cause each of its Subsidiaries to maintain, in force all licenses, approvals and agreements, the loss of which has or
could reasonably be expected to have a Material Adverse Effect.

 

6.2           Government
Compliance. Borrower shall meet, and shall cause each Subsidiary to meet, the minimum funding requirements of ERISA with respect
to any employee benefit plans subject to ERISA. Borrower shall comply, and shall cause each Subsidiary to comply, with all statutes,
laws, ordinances and government rules and regulations to which it is subject, noncompliance with which has or could reasonably
be expected to have a Material Adverse Effect.

 

6.3           Financial
Statements, Reports, Certificates. Borrower shall deliver the following to Bank: (a) as soon as available, but in any
event within thirty (30) days after the end of each calendar month, a company prepared consolidated balance sheet, income statement,
and cash flow statement covering Parent’s consolidated operations during such period, prepared in accordance with GAAP, consistently
applied (subject to normal and recurring year-end adjustments and the absence of notes), in a form acceptable to Bank and certified
by a Responsible Officer; (b) as soon as available, but in any event within ninety (90) days after the end of Parent’s
fiscal year, audited consolidated financial statements of Parent prepared in accordance with GAAP, consistently applied, together
with an unqualified opinion on such financial statements of an independent certified public accounting firm reasonably acceptable
to the Bank (it being agreed and understood that the firm Haskell & White LLP is acceptable to the Bank); (c) copies of all
statements, reports and notices sent or made available generally by Parent to its security holders or to any holders of Subordinated
Debt and, if applicable, all reports on Forms 10-K and 10-Q filed with the Securities and Exchange Commission; (d) promptly
upon receipt of notice thereof, a report of any legal actions pending or threatened against Parent or any Subsidiary that could
result in damages or costs to Parent or any Subsidiary of Two Hundred and Fifty Thousand Dollars ($250,000) or more; (e) as
soon as available, but in any event no later than the earlier to occur of thirty (30) days following the beginning of each fiscal
year or the date of approval by Parent’s board of directors, an annual operating budget and financial projections (including
income statements, balance sheets and cash flow statements) for such fiscal year, presented in a monthly format, approved by Parent’s
board of directors, and in a form and substance acceptable to Bank; and (f) such budgets, sales projections, operating plans
or other financial information as Bank may reasonably request from time to time.

 

Borrower shall deliver
to Bank with the monthly financial statements a Compliance Certificate signed by a Responsible Officer in substantially the form
of Exhibit C hereto.

 

Bank shall have a right
from time to time hereafter to audit Borrower’s Accounts and appraise Collateral at Borrower’s expense, provided that
such audits will be conducted no more often than every twelve (12) months unless an
Event of Default has occurred and is continuing.

 

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6.4           Inventory;
Returns. Borrower shall keep all Inventory in good and marketable condition, free from all material defects except for Inventory
for which adequate reserves have been made. Returns and allowances, if any, as between Borrower and its account debtors shall be
on the same basis and in accordance with the usual customary practices of Borrower, as they exist at the time of the execution
and delivery of this Agreement. Borrower shall promptly notify Bank of all returns and recoveries and of all disputes and claims,
where the return, recovery, dispute or claim involves more than Two Hundred and Fifty Thousand Dollars ($250,000).

 

6.5           Taxes.
Borrower shall make, and shall cause each Subsidiary to make, due and timely payment or deposit of all material federal, state,
and local taxes, assessments, or contributions required of it by law, and will execute and deliver to Bank, on demand, appropriate
certificates attesting to the payment or deposit thereof; and Borrower will make, and will cause each Subsidiary to make, timely
payment or deposit of all material tax payments and withholding taxes required of it by applicable laws, including, but not limited
to, those laws concerning F.I.C.A., F.U.T.A., state disability, and local, state, and federal income taxes, and will, upon request,
furnish Bank with proof satisfactory to Bank indicating that Borrower or a Subsidiary has made such payments or deposits; provided
that Borrower or a Subsidiary need not make any payment if the amount or validity of such payment is contested in good faith by
appropriate proceedings and is reserved against (to the extent required by GAAP) by Borrower.

 

6.6           Insurance.

 

(a)          Borrower,
at its expense, shall keep the Collateral insured against loss or damage by fire, theft, explosion, sprinklers, and all other hazards
and risks, and in such amounts, as ordinarily insured against by other owners in similar businesses conducted in the locations
where Borrower’s business is conducted on the date hereof. Borrower shall also maintain insurance relating to Borrower’s
business, ownership and use of the Collateral in amounts and of a type that are customary to businesses similar to Borrower’s.

 

(b)          All
such policies of insurance shall be in such form, with such companies, and in such amounts as are reasonably satisfactory to Bank.
All such policies of property insurance shall contain a lender’s loss payable endorsement, in a form satisfactory to Bank,
showing Bank as an additional loss payee thereof, and all liability insurance policies shall show the Bank as an additional insured
and shall specify that the insurer must give at least twenty (20) days notice to Bank before canceling its policy for any reason.
Upon Bank’s request, Borrower shall deliver to Bank certified copies of such policies of insurance and evidence of the payments
of all premiums therefor. All proceeds payable under any such policy shall, at the option of Bank, be payable to Bank to be applied
on account of the Obligations.

 

6.7           Accounts.
Borrower shall (i) maintain and shall cause each of its Subsidiaries and Parent to maintain its primary depository, operating,
and investment accounts with Bank (including, without limitation, all depository, operating, and investment accounts maintained
in the United States) and (ii) endeavor to utilize and shall cause each of its Subsidiaries and Parent to endeavor to utilize
Bank’s International Banking Division for any international banking services required by Borrower, including, but not limited
to, foreign currency wires, hedges and swaps. Notwithstanding the foregoing, (i) Borrower and Parent may continue to maintain
their respective accounts with PNC Bank that are identified on the Perfection Certificate on the Effective Date for a period of
up to 45 days after the Effective Date; provided, that at or prior to the end of such 45 day period, Borrower must deliver evidence
to the Bank of the closure of such accounts and transfer of all funds therein to one or more accounts maintained with the Bank;
provided, further, that during such 45 day period, the aggregate balance of all such accounts maintained with PNC Bank may not
exceed $500,000 at any time and all such accounts must be subject to one or more account control agreements, effective no later
than February 11, 2019, in such form and substance as are reasonably acceptable to the Bank, in favor of the Bank, and (ii) Parent
may continue to maintain its accounts with Royal Bank of Canada that are identified on the Perfection Certificate on the Effective
Date; provided, that, the aggregate balance in all such accounts may not exceed $250,000 at any time.

 

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6.8           Intellectual
Property Rights. On the Compliance Certificate next due hereunder, Borrower shall give Bank written notice of any applications
or registrations of intellectual property rights filed with the United States Patent and Trademark Office, including the date of
such filing and the registration or application numbers, if any. Borrower shall promptly give Bank written notice upon the filing
of any applications or registrations with the United States Copyright Office, including the title of such intellectual property
rights to be registered, as such title will appear on such applications or registrations, and the date such applications or registrations
will be filed. Upon filing any such applications or registrations with the United States Copyright Office, Borrower shall promptly
provide Bank with (i) a copy of such applications or registrations, without the exhibits, if any, thereto, (ii) evidence of the
filing of any documents requested by Bank to be filed for Bank to maintain the perfection and priority of its security interest
in such intellectual property rights, and (iii) the date of such filing.

 

Borrower and each of
its Subsidiaries shall: (a) use commercially reasonable efforts to protect, defend and maintain the validity and enforceability
of its Intellectual Property that is material to Borrower’s business; (b) promptly advise Bank in writing of infringement
by a third party of its Intellectual Property that is material to Borrower’s business; and (c) not allow any Intellectual
Property material to Borrower’s business to be abandoned, forfeited or dedicated to the public without Bank’s prior
written consent.

 

6.9           Landlord
Waivers; Bailee Waivers. In the event that Borrower or any of its Subsidiaries, after the Effective Date, intends to add any
new offices or business locations, including warehouses, or otherwise store any portion of the Collateral with, or deliver any
portion of the Collateral to, a bailee, in each case pursuant to Section 7.2, then Borrower or such Subsidiary will first
receive the written consent of Bank and, in the event that the Collateral at any new location is valued in excess of Two Hundred
and Fifty Thousand Dollars ($250,000) in the aggregate, such bailee or landlord, as applicable, must execute and deliver a bailee
waiver or landlord waiver, as applicable, in form and substance reasonably satisfactory to Bank prior to the addition of any new
offices or business locations, or any such storage with or delivery to any such bailee, as the case may be.

 

6.10         Creation/Acquisition
of Subsidiaries. In the event Borrower, or any of its Subsidiaries creates or acquires any Subsidiary, Borrower shall provide
prior written notice to Bank of the creation or acquisition of such new Subsidiary and take all such action as may be reasonably
required by Bank to cause each such Subsidiary to become a co-Borrower hereunder or to guarantee the Obligations of Borrower under
the Loan Documents and, in each case, grant a continuing pledge and security interest in and to the assets of such Subsidiary (as
described on Exhibit A hereto); and Borrower (or its Subsidiary, as applicable) shall grant and pledge to Bank a perfected
security interest in the all of the outstanding stock, units or other evidence of ownership of each such newly created Subsidiary.

 

6.11         Litigation
Cooperation. Commencing on the Effective Date and continuing through the termination of this Agreement, make available to Bank,
without expense to Bank, Borrower and each of Borrower’s officers, employees and agents and Borrower’s Books, to the
extent that Bank may reasonably deem them necessary to prosecute or defend any third-party suit or proceeding instituted by or
against Bank with respect to any Collateral or relating to Borrower.

 

6.12         Liquidity
Covenant. Commencing on the Closing Date, Borrower shall at all times maintain in accounts held at the Bank, unrestricted cash
and cash equivalents in an aggregate amount equal to at least three times the Monthly Cash Burn as calculated on the last date
of the immediately preceding month.

 

6.13         Further
Assurances. At any time and from time to time Borrower shall execute and deliver such further instruments and take such further
action as may reasonably be requested by Bank to effect the purposes of this Agreement.

 

7.          Negative
Covenants.

 

Commencing on the Effective
Date, Borrower will not do any of the following:

 

7.1           Dispositions.
Convey, sell, lease, transfer or otherwise dispose of (collectively, a “Transfer”), or permit any of its Subsidiaries
to Transfer, all or any part of its business or property, other than: (i) Transfers of Inventory in the ordinary course of
business; (ii) Transfers of non-exclusive licenses and similar arrangements for the use of the property (other than Intellectual
Property) of Borrower or its Subsidiaries in the ordinary course of business; (iii) Transfers of worn-out or obsolete Equipment
which was not financed by Bank; or (iv) Transfers consisting of Permitted Licenses.

 

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7.2           Change
in Business; Change in Control or Executive Office. Engage in any business, or permit any of its Subsidiaries to engage in
any business, other than the businesses currently engaged in by Borrower and any business substantially similar or related thereto
(or incidental thereto); or cease to conduct business in the manner conducted by Borrower as of the Effective Date; or suffer or
permit a Change in Control in which all Obligations to the Bank are not paid in full on the initial closing of such Change in Control
transaction; or without thirty (30) days prior written notification to Bank, relocate its chief executive office or state of incorporation
or change its legal name; or without Bank’s prior written consent, change the date on which its fiscal year ends. Furthermore,
Borrower shall not, without at least thirty (30) days’ prior written notice to Bank add any new offices or business locations,
including warehouses (unless such new offices or business locations contain less than Two Hundred and Fifty Thousand Dollars ($250,000)
in assets or property of Borrower or any of its Subsidiaries).

 

7.3           Mergers
or Acquisitions. Merge or consolidate, or permit any of its Subsidiaries to merge or consolidate, with or into any other business
organization, or acquire, or permit any of its Subsidiaries to acquire, all or substantially all of the capital stock or property
of another Person other than pursuant to a transaction in which all Obligations to the Bank are paid on the initial closing thereof.

 

7.4           Indebtedness.
Create, incur, assume or be or remain liable with respect to any Indebtedness, or permit any Subsidiary so to do, other than Permitted
Indebtedness.

 

7.5           Encumbrances.
Create, incur, assume or suffer to exist any Lien with respect to any of its property (including without limitation, its Intellectual
Property), or assign or otherwise convey any right to receive income, including the sale of any Accounts, or permit any of its
Subsidiaries to do so, except for Permitted Liens, or agree with any Person other than Bank not to grant a security interest in,
or otherwise encumber, any of its property (including without limitation, its Intellectual Property), or permit any Subsidiary
to do so.

 

7.6           Distributions.
Pay any dividends or make any other distribution or payment on account of or in redemption, retirement or purchase of any capital
stock, or permit any of its Subsidiaries to do so, except that Borrower may repurchase the stock of former employees pursuant to
stock repurchase agreements as long as an Event of Default does not exist prior to such repurchase or would not exist after giving
effect to such repurchase.

 

7.7           Investments.
Directly or indirectly acquire or own, or make any Investment in or to any Person, or permit any of its Subsidiaries so to do,
other than Permitted Investments; or maintain or invest any of its property with a Person other than Bank or permit any of its
Subsidiaries to do so unless such Person has entered into an account control agreement with Bank in form and substance satisfactory
to Bank; or suffer or permit any Subsidiary to be a party to, or be bound by, an agreement that restricts such Subsidiary from
paying dividends or otherwise distributing property to Borrower.

 

7.8           Transactions
with Affiliates. Directly or indirectly enter into or permit to exist any material transaction with any Affiliate of Borrower
except for transactions that are in the ordinary course of Borrower’s business, upon fair and reasonable terms that are no
less favorable to Borrower than would be obtained in an arm’s length transaction with a non-affiliated Person.

 

7.9           Subordinated
Debt. Make any payment in respect of any Subordinated Debt, or permit any of its Subsidiaries to make any such payment, except
in compliance with the terms of such Subordinated Debt, or amend any provision contained in any documentation relating to the Subordinated
Debt without Bank’s prior written consent.

 

7.10         Inventory
and Equipment. Store the Inventory or the Equipment with a bailee, warehouseman, or other third party unless the third party
has been notified of Bank’s security interest and Bank (a) has received an acknowledgment from the third party that it is
holding or will hold the Inventory or Equipment for Bank’s benefit or (b) is in pledge possession of the warehouse receipt,
where negotiable, covering such Inventory or Equipment. Store or maintain any Equipment or Inventory at a location other than the
location set forth in Section 10 of this Agreement.

 

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7.11         Compliance.
Become an “investment company” or be controlled by an “investment company,” within the meaning of the Investment
Company Act of 1940, or become principally engaged in, or undertake as one of its important activities, the business of extending
credit for the purpose of purchasing or carrying margin stock, or use the proceeds of any Credit Extension for such purpose. Fail
to meet the minimum funding requirements of ERISA, permit a Reportable Event or Prohibited Transaction, as defined in ERISA, to
occur, fail to comply with the Federal Fair Labor Standards Act or violate any law or regulation, which violation has or could
reasonably be expected to have a Material Adverse Effect, or a material adverse effect on the Collateral or the priority of Bank’s
Lien on the Collateral, or permit any of its Subsidiaries to do any of the foregoing, or permit any of its Subsidiaries to do any
of the foregoing.

 

7.12         Capital
Expenditures. Make or contract to make, without Bank’s prior written consent, capital expenditures, including leasehold
improvements, in any fiscal year in excess of $250,000.00 or incur liability for rentals of property (including both real and personal
property) in an amount which, together with capital expenditures, shall in any fiscal year exceed such sum.

 

7.13         Compliance
with Anti-Terrorism Laws. Bank hereby notifies Borrower and each of its Subsidiaries that pursuant to the requirements of Anti-Terrorism
Laws, and Bank’s policies and practices, Bank is required to obtain, verify and record certain information and documentation
that identifies Borrower and each of its Subsidiaries and their principals, which information includes the name and address of
Borrower and each of its Subsidiaries and their principals and such other information that will allow Bank to identify such party
in accordance with Anti-Terrorism Laws. Neither Borrower nor any of its Subsidiaries shall, nor shall Borrower or any of its Subsidiaries
permit any Affiliate to, directly or indirectly, knowingly enter into any documents, instruments, agreements or contracts with
any Person listed on the OFAC Lists. Borrower and each of its Subsidiaries shall immediately notify Bank if Borrower or such Subsidiary
has knowledge that Borrower, or any Subsidiary or Affiliate of Borrower, is listed on the OFAC Lists or (a) is convicted on,
(b) pleads nolo contendere to, (c) is indicted on, or (d) is arraigned and held over on charges involving
money laundering or predicate crimes to money laundering. Neither Borrower nor any of its Subsidiaries shall, nor shall Borrower
or any of its Subsidiaries, permit any Affiliate to, directly or indirectly, (i) conduct any business or engage in any transaction
or dealing with any Blocked Person, including, without limitation, the making or receiving of any contribution of funds, goods
or services to or for the benefit of any Blocked Person, (ii) deal in, or otherwise engage in any transaction relating to,
any property or interests in property blocked pursuant to Executive Order No. 13224 or any similar executive order or other Anti-Terrorism
Law, or (iii) engage in or conspire to engage in any transaction that evades or avoids, or has the purpose of evading or avoiding,
or attempts to violate, any of the prohibitions set forth in Executive Order No. 13224 or other Anti-Terrorism Law.

 

8.          Events
of Default.

 

Any one or more of
the following events shall constitute an Event of Default by Borrower under this Agreement:

 

8.1           Payment
Default. If Borrower fails to pay, when due, any of the Obligations;

 

8.2           Covenant
Default.

 

(a)          If
Borrower fails to perform any obligation under Article 6 or violates any of the covenants contained in Article 7 of this Agreement;
or

 

(b)          If
Borrower fails or neglects to perform or observe any other material term, provision, condition, covenant contained in this Agreement,
in any of the Loan Documents, or in any other present or future agreement between Borrower and Bank and as to any default under
such other term, provision, condition or covenant that can be cured, has failed to cure such default within ten Business Days after
Borrower receives notice thereof or any officer of Borrower becomes aware thereof; provided, however, that if the default cannot
by its nature be cured within the ten Business Day period or cannot after diligent attempts by Borrower be cured within such ten
Business Day period, and such default is likely to be cured within a reasonable time, then Borrower shall have an additional reasonable
period (which shall not in any case exceed 30 days) to attempt to cure such default, and within such reasonable time period the
failure to have cured such default shall not be deemed an Event of Default but no Credit Extensions will be made.

 

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8.3           Material
Adverse Effect. If there occurs any circumstance or circumstances that has or could reasonably be expected to have a Material
Adverse Effect;

 

8.4           Attachment.
If any portion of Borrower’s assets is attached, seized, subjected to a writ or distress warrant, or is levied upon, or comes
into the possession of any trustee, receiver or person acting in a similar capacity and such attachment, seizure, writ or distress
warrant or levy has not been removed, discharged or rescinded within ten (10) Business Days, or if Borrower is enjoined, restrained,
or in any way prevented by court order from continuing to conduct all or any material part of its business affairs, or if a judgment
or other claim becomes a lien or encumbrance upon any material portion of Borrower’s assets, or if a notice of lien, levy,
or assessment is filed of record with respect to any of Borrower’s assets by the United States Government, or any department,
agency, or instrumentality thereof, or by any state, county, municipal, or governmental agency, and the same is not paid within
ten (10) Business Days after Borrower receives notice thereof, provided that none of the foregoing shall constitute an Event of
Default where such action or event is stayed or an adequate bond has been posted pending a good faith contest by Borrower (provided
that no Credit Extensions will be required to be made during such cure period);

 

8.5           Insolvency.
If Borrower becomes insolvent, or if an Insolvency Proceeding is commenced by Borrower, or if an Insolvency Proceeding is commenced
against Borrower and is not dismissed or stayed within thirty (30) days (provided that no Credit Extensions will be made prior
to the dismissal of such Insolvency Proceeding);

 

8.6           Other
Agreements. If there is a default or other failure to perform in any agreement to which Borrower is a party or by which it
is bound resulting in a right by a third party or parties, whether or not exercised, to accelerate the maturity of any Indebtedness
in an amount in excess of Two Hundred and Fifty Thousand Dollars ($250,000) or which has or could reasonably be expected to have
a Material Adverse Effect;

 

8.7           Judgments.
If a judgment or judgments for the payment of money in an amount, individually or in the aggregate, of at least Two Hundred and
Fifty Thousand Dollars ($250,000) shall be rendered against Borrower and shall remain unsatisfied and unstayed for a period of
ten (10) Business Days (provided that no Credit Extensions will be made prior to the satisfaction or stay of such judgment); or

 

8.8           Misrepresentations.
If any material misrepresentation or material misstatement exists now or hereafter in any warranty or representation set forth
herein or in any certificate delivered to Bank by any Responsible Officer pursuant to this Agreement or to induce Bank to enter
into this Agreement or any other Loan Document.

 

8.9           Subordinated
Debt. A default or breach occurs under any agreement between Borrower or any of its Subsidiaries and any creditor of Borrower
or any of its Subsidiaries that signed a subordination, intercreditor, or other similar agreement with Bank, or any creditor that
has signed such an agreement with Bank breaches any terms of such agreement.

 

8.10         Governmental
Approvals. Any consent, authorization, approval, order, license, franchise, permit, certificate, accreditation, registration,
filing or notice, of, issued by, from or to, or other act by or in respect of, any governmental authority shall have been revoked,
rescinded, suspended, modified in an adverse manner, or not renewed in the ordinary course for a full term and such revocation,
rescission, suspension, modification or non-renewal has resulted in or could reasonably be expected to result in a Material Adverse
Effect.

 

    	20

     

    

 

8.11         Parent
Loan Document Default. An Event of Default (as defined in the Parent Loan Documents) occurs under any one of the Parent Loan
Documents.

 

9.          Bank’s
Rights and Remedies.

 

9.1           Rights
and Remedies. Upon the occurrence and during the continuance of an Event of Default, Bank may, at its election, without notice
of its election and without demand, do any one or more of the following, all of which are authorized by Borrower:

 

(a)          Declare
all Obligations, whether evidenced by this Agreement, by any of the other Loan Documents, or otherwise, immediately due and payable
(provided that upon the occurrence of an Event of Default described in Section 8.5, all Obligations shall become immediately
due and payable without any action by Bank);

 

(b)          Cease
advancing money or extending credit to or for the benefit of Borrower under this Agreement or under any other agreement between
Borrower and Bank;

 

(c)          Settle
or adjust disputes and claims directly with account debtors for amounts, upon terms and in whatever order that Bank reasonably
considers advisable;

 

(d)          Make
such payments and do such acts as Bank considers necessary or reasonable to protect its security interest in the Collateral. Borrower
agrees to assemble the Collateral if Bank so requires, and to make the Collateral available to Bank as Bank may designate. Borrower
authorizes Bank to enter the premises where the Collateral is located, to take and maintain possession of the Collateral, or any
part of it, and to pay, purchase, contest, or compromise any encumbrance, charge, or lien which in Bank’s determination appears
to be prior or superior to its security interest and to pay all expenses incurred in connection therewith. With respect to any
of Borrower’s owned premises, Borrower hereby grants Bank a license to enter into possession of such premises and to occupy
the same, without charge, in order to exercise any of Bank’s rights or remedies provided herein, at law, in equity, or otherwise;

 

(e)          Set
off and apply to the Obligations any and all (i) balances and deposits of Borrower held by Bank, or (ii) indebtedness
at any time owing to or for the credit or the account of Borrower held by Bank;

 

(f)          Ship,
reclaim, recover, store, finish, maintain, repair, prepare for sale, advertise for sale, and sell (in the manner provided for herein)
the Collateral. Bank is hereby granted a license or other right, solely pursuant to the provisions of this Section 9.1, to
use, without charge, Borrower’s labels, patents, copyrights, rights of use of any name, trade secrets, trade names, trademarks,
service marks, and advertising matter, or any property of a similar nature, as it pertains to the Collateral, in completing production
of, advertising for sale, and selling any Collateral and, in connection with Bank’s exercise of its rights under this Section 9.1,
Borrower’s rights under all licenses and all franchise agreements shall inure to Bank’s benefit;

 

(g)          Dispose
of the Collateral by way of one or more contracts or transactions, for cash or on terms, in such manner and at such places (including
Borrower’s premises) as Bank determines is commercially reasonable, and apply any proceeds to the Obligations in whatever
manner or order Bank deems appropriate;

 

(h)          Bank
may credit bid and purchase at any public sale; and

 

(i)          Any
deficiency that exists after disposition of the Collateral as provided above will be paid immediately by Borrower.

 

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9.2           Power
of Attorney. Effective only upon the occurrence and during the continuance of an Event of Default, Borrower hereby irrevocably
appoints Bank (and any of Bank’s designated officers, or employees) as Borrower’s true and lawful attorney to: (a)
send requests for verification of Accounts or notify account debtors of Bank’s security interest in the Accounts; (b) endorse
Borrower’s name on any checks or other forms of payment or security that may come into Bank’s possession; (c) sign
Borrower’s name on any invoice or bill of lading relating to any Account, drafts against account debtors, schedules and assignments
of Accounts, verifications of Accounts, and notices to account debtors; (d) dispose of any Collateral; (e) make, settle, and adjust
all claims under and decisions with respect to Borrower’s policies of insurance; (f) settle and adjust disputes and claims
respecting the accounts directly with account debtors, for amounts and upon terms which Bank determines to be reasonable; and (g)
to file, in its sole discretion, one or more financing or continuation statements and amendments thereto, relative to any of the
Collateral. The appointment of Bank as Borrower’s attorney in fact, and each and every one of Bank’s rights and powers,
being coupled with an interest, is irrevocable until all of the Obligations have been fully repaid and performed and Bank’s
obligation to provide Credit Extensions hereunder is terminated.

 

9.3           Accounts
Collection. At any time after the occurrence of an Event of Default, Bank may notify any Person owing funds to Borrower of
Bank’s security interest in such funds and verify the amount of such Account. Borrower shall collect all amounts owing to
Borrower for Bank, receive in trust all payments as Bank’s trustee, and immediately deliver such payments to Bank in their
original form as received from the account debtor, with proper endorsements for deposit.

 

9.4           Bank
Expenses. If Borrower fails to pay any amounts or furnish any required proof of payment due to third persons or entities, as
required under the terms of this Agreement, then Bank may do any or all of the following after reasonable notice to Borrower: (a) make
payment of the same or any part thereof; (b) set up such reserves under a loan facility in Section 2.1 as Bank deems necessary
to protect Bank from the exposure created by such failure; or (c) obtain and maintain insurance policies of the type discussed
in Section 6.6 of this Agreement, and take any action with respect to such policies as Bank deems prudent. Any amounts so
paid or deposited by Bank shall constitute Bank Expenses, shall be immediately due and payable, and shall bear interest at the
then applicable rate hereinabove provided, and shall be secured by the Collateral. Any payments made by Bank shall not constitute
an agreement by Bank to make similar payments in the future or a waiver by Bank of any Event of Default under this Agreement.

 

9.5           Bank’s
Liability for Collateral. So long as Bank complies with reasonable banking practices, Bank shall not in any way or manner be
liable or responsible for: (a) the safekeeping of the Collateral; (b) any loss or damage thereto occurring or arising
in any manner or fashion from any cause; (c) any diminution in the value thereof; or (d) any act or default of any carrier,
warehouseman, bailee, forwarding agency, or other person whomsoever. All risk of loss, damage or destruction of the Collateral
shall be borne by Borrower.

 

9.6           Remedies
Cumulative. Bank’s rights and remedies under this Agreement, the Loan Documents, and all other agreements shall be cumulative.
Bank shall have all other rights and remedies not inconsistent herewith as provided under the Code, by law, or in equity. No exercise
by Bank of one right or remedy shall be deemed an election, and no waiver by Bank of any Event of Default on Borrower’s part
shall be deemed a continuing waiver. No delay by Bank shall constitute a waiver, election, or acquiescence by it. No waiver by
Bank shall be effective unless made in a written document signed on behalf of Bank and then shall be effective only in the specific
instance and for the specific purpose for which it was given.

 

9.7           Demand;
Protest. Borrower waives demand, protest, notice of protest, notice of default or dishonor, notice of payment and nonpayment,
notice of any default, nonpayment at maturity, release, compromise, settlement, extension, or renewal of accounts, documents, instruments,
chattel paper, and guarantees at any time held by Bank on which Borrower may in any way be liable.

 

10.         Notices.

 

All notices, consents,
requests, approvals, demands, or other communication by any party to this Agreement or any other Loan Document must be in writing
and shall be deemed to have been validly served, given, or delivered: (a) upon the earlier of actual receipt and three (3) Business
Days after deposit in the U.S. mail, first class, registered or certified mail return receipt requested, with proper postage prepaid;
(b) upon transmission, when sent by electronic mail; (c) one (1) Business Day after deposit with a reputable overnight courier
with all charges prepaid; or (d) when delivered, if hand-delivered by messenger, all of which shall be addressed to the party to
be notified and sent to the address, facsimile number, or email address indicated below. Bank or Borrower may change its mailing
or electronic mail address or facsimile number by giving the other party written notice thereof in accordance with the terms of
this Section 10.

 

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	If to Borrower:	FENNEC PHARMACEUTICALS, INC.
	 	68 TW Alexander Drive
	 	Research Triangle Park, NC 27709
	 	Attn: Robert Andrade, CEO
	 	EMAIL:  randrade@fennecpharma.com
	 	 
	If to Bank:	Bridge Bank, a division of Western Alliance Bank
	 	12220 El Camino Real, Suite 100
	 	San Diego, CA 92130
	 	Attn:  Bill Wickline
	 	EMAIL:  bill.wickline@bridgebank.com

 

The parties hereto
may change the address at which they are to receive notices hereunder, by notice in writing in the foregoing manner given to the
other.

 

11.         CHOICE
OF LAW AND VENUE; JURY TRIAL WAIVER.

 

This Agreement shall
be governed by, and construed in accordance with, the internal laws of the State of California, without regard to principles of
conflicts of law. Each of Borrower and Bank hereby submits to the exclusive jurisdiction of the state and Federal courts located
in the County of Santa Clara, State of California. BORROWER AND BANK EACH HEREBY WAIVE THEIR RESPECTIVE RIGHTS TO A JURY TRIAL
OF ANY CLAIM OR CAUSE OF ACTION BASED UPON OR ARISING OUT OF ANY OF THE LOAN DOCUMENTS OR ANY OF THE TRANSACTIONS CONTEMPLATED
THEREIN, INCLUDING CONTRACT CLAIMS, TORT CLAIMS, BREACH OF DUTY CLAIMS, AND ALL OTHER COMMON LAW OR STATUTORY CLAIMS. EACH PARTY
RECOGNIZES AND AGREES THAT THE FOREGOING WAIVER CONSTITUTES A MATERIAL INDUCEMENT FOR IT TO ENTER INTO THIS AGREEMENT. EACH PARTY
REPRESENTS AND WARRANTS THAT IT HAS REVIEWED THIS WAIVER WITH ITS LEGAL COUNSEL AND THAT IT KNOWINGLY AND VOLUNTARILY WAIVES ITS
JURY TRIAL RIGHTS FOLLOWING CONSULTATION WITH LEGAL COUNSEL.

 

12.         JUDICIAL
REFERENCE PROVISION.

 

12.1         In
the event the Jury Trial Waiver set forth above is not enforceable, the parties elect to proceed under this Judicial Reference
Provision.

 

12.2         With
the exception of the items specified in Section 12.3, below, any controversy, dispute or claim (each, a “Claim”)
between the parties arising out of or relating to this Agreement or any other document, instrument or agreement between the undersigned
parties (collectively in this Section, the “Loan Documents”), will be resolved by a reference proceeding
in California in accordance with the provisions of Sections 638 et seq. of the California Code of Civil Procedure (“CCP”),
or their successor sections, which shall constitute the exclusive remedy for the resolution of any Claim, including whether the
Claim is subject to the reference proceeding. Except as otherwise provided in the Loan Documents, venue for the reference proceeding
will be in the state or federal court in the county or district where the real property involved in the action, if any, is located
or in the state or federal court in the county or district where venue is otherwise appropriate under applicable law (the “Court”).

 

12.3         The
matters that shall not be subject to a reference are the following: (i) nonjudicial foreclosure of any security interests in real
or personal property, (ii) exercise of self-help remedies (including, without limitation, set-off), (iii) appointment of a receiver
and (iv) temporary, provisional or ancillary remedies (including, without limitation, writs of attachment, writs of possession,
temporary restraining orders or preliminary injunctions). This reference provision does not limit the right of any party to exercise
or oppose any of the rights and remedies described in clauses (i) and (ii) or to seek or oppose from a court of competent jurisdiction
any of the items described in clauses (iii) and (iv). The exercise of, or opposition to, any of those items does not waive the
right of any party to a reference pursuant to this reference provision as provided herein.

 

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12.4         The
referee shall be a retired judge or justice selected by mutual written agreement of the parties. If the parties do not agree within
ten (10) days of a written request to do so by any party, then, upon request of any party, the referee shall be selected by the
Presiding Judge of the Court (or his or her representative). A request for appointment of a referee may be heard on an ex parte
or expedited basis, and the parties agree that irreparable harm would result if ex parte relief is not granted. Pursuant to CCP
§ 170.6, each party shall have one peremptory challenge to the referee selected by the Presiding Judge of the Court (or his
or her representative).

 

12.5         The
parties agree that time is of the essence in conducting the reference proceedings. Accordingly, the referee shall be requested,
subject to change in the time periods specified herein for good cause shown, to (i) set the matter for a status and trial-setting
conference within fifteen (15) days after the date of selection of the referee, (ii) if practicable, try all issues of law or fact
within one hundred twenty (120) days after the date of the conference and (iii) report a statement of decision within twenty (20)
days after the matter has been submitted for decision.

 

12.6         The
referee will have power to expand or limit the amount and duration of discovery. The referee may set or extend discovery deadlines
or cutoffs for good cause, including a party’s failure to provide requested discovery for any reason whatsoever. Unless otherwise
ordered based upon good cause shown, no party shall be entitled to “priority” in conducting discovery, depositions
may be taken by either party upon seven (7) days written notice, and all other discovery shall be responded to within fifteen (15)
days after service. All disputes relating to discovery which cannot be resolved by the parties shall be submitted to the referee
whose decision shall be final and binding.

 

12.7         Except
as expressly set forth herein, the referee shall determine the manner in which the reference proceeding is conducted including
the time and place of hearings, the order of presentation of evidence, and all other questions that arise with respect to the course
of the reference proceeding. All proceedings and hearings conducted before the referee, except for trial, shall be conducted without
a court reporter, except that when any party so requests, a court reporter will be used at any hearing conducted before the referee,
and the referee will be provided a courtesy copy of the transcript. The party making such a request shall have the obligation to
arrange for and pay the court reporter. Subject to the referee’s power to award costs to the prevailing party, the parties
will equally share the cost of the referee and the court reporter at trial.

 

12.8         The
referee shall be required to determine all issues in accordance with existing case law and the statutory laws of the State of California.
The rules of evidence applicable to proceedings at law in the State of California will be applicable to the reference proceeding.
The referee shall be empowered to enter equitable as well as legal relief, enter equitable orders that will be binding on the parties
and rule on any motion which would be authorized in a court proceeding, including without limitation motions for summary judgment
or summary adjudication. The referee shall issue a decision at the close of the reference proceeding which disposes of all claims
of the parties that are the subject of the reference. Pursuant to CCP § 644, such decision shall be entered by the Court as
a judgment or an order in the same manner as if the action had been tried by the Court and any such decision will be final, binding
and conclusive. The parties reserve the right to appeal from the final judgment or order or from any appealable decision or order
entered by the referee. The parties reserve the right to findings of fact, conclusions of laws, a written statement of decision,
and the right to move for a new trial or a different judgment, which new trial, if granted, is also to be a reference proceeding
under this provision.

 

12.9         If
the enabling legislation which provides for appointment of a referee is repealed (and no successor statute is enacted), any dispute
between the parties that would otherwise be determined by reference procedure will be resolved and determined by arbitration. The
arbitration will be conducted by a retired judge or justice, in accordance with the California Arbitration Act §1280 through
§1294.2 of the CCP as amended from time to time. The limitations with respect to discovery set forth above shall apply to
any such arbitration proceeding.

 

    	24

     

    

 

12.10      THE
PARTIES RECOGNIZE AND AGREE THAT ALL CONTROVERSIES, DISPUTES AND CLAIMS RESOLVED UNDER THIS REFERENCE PROVISION WILL BE DECIDED
BY A REFEREE AND NOT BY A JURY. AFTER CONSULTING (OR HAVING HAD THE OPPORTUNITY TO CONSULT) WITH COUNSEL OF ITS, HIS OR HER OWN
CHOICE, EACH PARTY KNOWINGLY AND VOLUNTARILY, AND FOR THE MUTUAL BENEFIT OF ALL PARTIES, AGREES THAT THIS REFERENCE PROVISION
WILL APPLY TO ANY CONTROVERSY, DISPUTE OR CLAIM BETWEEN OR AMONG THEM ARISING OUT OF OR IN ANY WAY RELATED TO, THIS AGREEMENT
OR THE OTHER LOAN DOCUMENTS.

 

13.         General
Provisions.

 

13.1         Successors
and Assigns. This Agreement shall bind and inure to the benefit of the respective successors and permitted assigns of each
of the parties; provided, however, that neither this Agreement nor any rights hereunder may be assigned by Borrower without Bank’s
prior written consent, which consent may be granted or withheld in Bank’s sole discretion. Bank shall have the right without
the consent of or notice to Borrower to sell, transfer, negotiate, or grant participation in all or any part of, or any interest
in, Bank’s obligations, rights and benefits hereunder.

 

13.2         Indemnification.
Borrower shall defend, indemnify and hold harmless Bank and its officers, employees, and agents against: (a) all obligations,
demands, claims, and liabilities claimed or asserted by any other party in connection with the transactions contemplated by this
Agreement; and (b) all losses or Bank Expenses in any way suffered, incurred, or paid by Bank as a result of or in any way
arising out of, following, or consequential to transactions between Bank and Borrower whether under this Agreement, or otherwise
(including without limitation reasonable attorneys’ fees and expenses), except for losses caused by Bank’s gross negligence
or willful misconduct.

 

13.3         Time
of Essence. Time is of the essence for the performance of all obligations set forth in this Agreement.

 

13.4         Severability
of Provisions. Each provision of this Agreement shall be severable from every other provision of this Agreement for the purpose
of determining the legal enforceability of any specific provision.

 

13.5         Amendments
in Writing, Integration. Neither this Agreement nor the Loan Documents can be amended or terminated orally. All prior agreements,
understandings, representations, warranties, and negotiations between the parties hereto with respect to the subject matter of
this Agreement and the Loan Documents, if any, are merged into this Agreement and the Loan Documents.

 

13.6         Counterparts.
This Agreement may be executed in any number of counterparts and by different parties on separate counterparts, each of which,
when executed and delivered, shall be deemed to be an original, and all of which, when taken together, shall constitute but one
and the same Agreement.

 

13.7         Survival.
All covenants, representations and warranties made in this Agreement shall continue in full force and effect so long as any Obligations
remain outstanding or Bank has any obligation to make Credit Extensions to Borrower. The obligations of Borrower to indemnify Bank
with respect to the expenses, damages, losses, costs and liabilities described in Section 13.2 shall survive until all applicable
statute of limitations periods with respect to actions that may be brought against Bank have run.

 

13.8         Confidentiality.
In handling any confidential information Bank and all employees and agents of Bank, including but not limited to accountants, shall
exercise the same degree of care that it exercises with respect to its own proprietary information of the same types to maintain
the confidentiality of any non-public information thereby received or received pursuant to this Agreement except that disclosure
of such information may be made (i) to the subsidiaries or affiliates of Bank in connection with their present or prospective
business relations with Borrower, (ii) to prospective transferees or purchasers of any interest in the Loans, (iii) as
required by law, regulations, rule or order, subpoena, judicial order or similar order, (iv) as may be required in connection
with the examination, audit or similar investigation of Bank and (v) as Bank may determine in connection with the enforcement
of any remedies hereunder. Confidential information hereunder shall not include information that either: (a) is in the public
domain or in the knowledge or possession of Bank when disclosed to Bank, or becomes part of the public domain after disclosure
to Bank through no fault of Bank; or (b) is disclosed to Bank by a third party, provided Bank does not have actual knowledge
that such third party is prohibited from disclosing such information.

 

    	25

     

    

 

13.9         Patriot
Act Notice.  Bank notifies Borrower that, pursuant to the requirements of the USA Patriot Act, Title III of Pub. L. 107-56
(signed into law on October 26, 2001) (the “ Patriot Act”), it is required to obtain, verify and record information
that identifies Borrower, which information includes names and addresses and other information that will allow Bank to identify
the Borrower in accordance with the Patriot Act.

 

14.         NOTICE
OF FINAL AGREEMENT.

 

BY
SIGNING THIS DOCUMENT EACH PARTY REPRESENTS AND AGREES THAT: (A) THIS WRITTEN AGREEMENT REPRESENTS THE FINAL AGREEMENT BETWEEN
THE PARTIES, (B) THERE ARE NO UNWRITTEN ORAL AGREEMENTS BETWEEN THE PARTIES, AND (C) THIS WRITTEN AGREEMENT MAY NOT BE CONTRADICTED
BY EVIDENCE OF ANY PRIOR, CONTEMPORANEOUS, OR SUBSEQUENT ORAL AGREEMENTS OR UNDERSTANDINGS OF THE PARTIES.

 

    	26

     

    

 

IN WITNESS WHEREOF, the parties hereto
have caused this Agreement to be executed as of the date first above written.

 

	 	Fennec Pharmaceuticals, Inc., a Delaware corporation
	 	 
	 	By:	                  
	 	 	 
	 	Title:	 
	 	 	 
	 	Western Alliance Bank, AN ARIZONA CORPORATION
	 	 
	 	By:	 
	 	 	 
	 	Title:	 

 

     

     

    

 

EXHIBIT A

 

	DEBTOR:	FENNEC PHARMACEUTICALS, INC.
	 	 
	SECURED PARTY:	WESTERN ALLIANCE BANK, an Arizona corporation

 

COLLATERAL
DESCRIPTION ATTACHMENT

TO LOAN AND SECURITY AGREEMENT

 

All personal property
of Borrower (herein referred to as “Borrower” or “Debtor”) whether presently existing or hereafter created
or acquired, and wherever located, including, but not limited to:

 

(a)        all
accounts (including health-care-insurance receivables), chattel paper (including tangible and electronic chattel paper), deposit
accounts, documents (including negotiable documents), equipment (including all accessions and additions thereto), general intangibles
(including payment intangibles and software), goods (including fixtures), instruments (including promissory notes), inventory (including
all goods held for sale or lease or to be furnished under a contract of service, and including returns and repossessions), investment
property (including securities and securities entitlements), letter of credit rights, money, and all of Debtor’s books and
records with respect to any of the foregoing, and the computers and equipment containing said books and records;

 

(b)        any
and all cash proceeds and/or noncash proceeds of any of the foregoing, including, without limitation, insurance proceeds, and all
supporting obligations and the security therefor or for any right to payment. All terms above have the meanings given to them in
the California Uniform Commercial Code, as amended or supplemented from time to time.

 

Notwithstanding the
foregoing, the Collateral shall not include any copyrights, patents, trademarks, servicemarks and applications therefor, now owned
or hereafter acquired, or any claims for damages by way of any past, present and future infringement of any of the foregoing (collectively,
the “Intellectual Property”); provided, however, that the Collateral shall include all accounts and general intangibles
that consist of rights to payment and proceeds from the sale, licensing or disposition of all or any part, or rights in, the foregoing
(the “Rights to Payment”). Notwithstanding the foregoing, if a judicial authority (including a U.S. Bankruptcy Court)
holds that a security interest in the underlying Intellectual Property is necessary to have a security interest in the Rights to
Payment, then the Collateral shall automatically, and effective as of the Effective Date, include the Intellectual Property to
the extent necessary to permit perfection of Bank’s security interest in the Rights to Payment.

 

     

     

    

 

Exhibit
B-1

 

DISBURSEMENT
LETTER

[____] __, 20[_]

 

The undersigned, being
the duly elected and acting __________________ of                           FENNEC PHARMACEUTICALS, INC., a Delaware corporation (“Borrower”),
does hereby certify to WESTERN ALLIANCE BANK, an Arizona corporation (“Bank”), in connection with that
certain Loan and Security Agreement dated as of January [___], 2019, by and among Borrower and Bank (the “Loan Agreement”;
with other capitalized terms used below having the meanings ascribed thereto in the Loan Agreement) that:

 

1.         The
representations and warranties made by Borrower in Section 5 of the Loan Agreement and in the other Loan Documents are true
and correct in all material respects as of the date hereof.

 

2.         No
event or condition has occurred that would constitute an Event of Default under the Loan Agreement or any other Loan Document.

 

3.         Borrower
is in compliance with the covenants and requirements contained in Sections 5, 6 and 7 of the Loan Agreement.

 

4.         All
conditions referred to in Section 3 of the Loan Agreement to the making of the Loan to be made on or about the date hereof
have been satisfied or waived by Bank.

 

5.         No
Material Adverse Effect has occurred.

 

6.         The
undersigned is a Responsible Officer.

 

[Balance of Page
Intentionally Left Blank]

 

     

     

    

 

7.          The
proceeds of the Term Loan shall be disbursed as follows:

 

	Disbursement from Bank:	 	 	 
	Loan Amount	 	$	12,500,000.00	 
	 	 	 	 	 
	Less:	 	 	 	 
	--Loan Fee	 	$	([_______])	 
	--Interim Interest	 	$	(________)	 
	--Bank’s Legal Fees	 	$	(________)	*
	 	 	 	 	 
	TOTAL TERM LOAN NET PROCEEDS	 	$	_______________
	 

 

8.          The
aggregate net proceeds of the Term Loan shall be transferred to the Designated Deposit Account as follows:

 

	Account Name:	FENNEC PHARMACEUTICALS, INC.
	Bank Name:	[                       ]
	Bank Address:	[                       

                            ]
	Account Number:	 	 
	ABA Number:	[                       ]

 

[Balance
of Page Intentionally Left Blank]

 

* Legal fees and costs
are through the Closing Date. Post-closing legal fees and costs, payable after the Closing Date, to be invoiced and paid post-closing.

 

     

     

    

 

Dated as of the date
first set forth above.

 

	BORROWER:	 
	 	 
	FENNEC PHARMACEUTICALS, INC., 	 
	a Delaware corporation	 
	 	 	 
	By	                        	 
	Name:	 	 
	Title:	 	 
	 	 	 
	BANK:	 
	 	 
	WESTERN ALLIANCE BANK, 	 
	an Arizona corporation	 
	 	 	 
	By	 	 
	Name:	 	 
	Title:	 	 

 

[Signature Page to Disbursement Letter]

 

     

     

    

 

EXHIBIT B-2

 

Loan Payment/Advance
Request Form

 

To be submitted no later than 3:00 PM
to be considered for same day processing)

 

	To:	Western Alliance Bank, an Arizona corporation	 

 

	Fax:	[(408) 282-1681]	 

 

	Date:	 	 

 

	From:	 	 
	 	Borrower's Name	 

 

	 	 	 
	 	Authorized Signature	 

 

	 	 	 
	 	Authorized Signer's Name (please print)	 

 

	 	 	 
	 	Phone Number	 

 

	To Account #	 	 

 

Borrower hereby requests funding in the
amount of $ _______ in accordance with the Term Loan as defined in the Loan and Security Agreement dated _______________, 2019.

 

Borrower hereby authorizes the Bank to
rely on facsimile stamp signatures and treat them as authorized by Borrower for the purpose of requesting the above advance.

 

All representations and warranties of Borrower
stated in the Loan and Security Agreement are true, correct and complete in all material respects as of the date of this request;
provided that those representations and warranties expressly referring to another date shall be true, correct and complete
in all material respects as of such date.

 

Capitalized terms used
herein and not otherwise defined have the meanings set forth in the Loan and Security Agreement.

 

     

     

    

 

Exhibit
C

Compliance
Certificate

 

	TO:	WESTERN ALLIANCE BANK, an Arizona corporation
	 	 
	FROM:	 	 

 

The undersigned authorized
officer of FENNEC PHARMACEUTICALS, INC. hereby certifies that in accordance with the terms and conditions of the Loan and Security
Agreement between Borrower and Bank (the “Agreement”), (i) Borrower is in complete compliance for the period ending
_______________ with all required covenants except as noted below and (ii) all representations and warranties of Borrower stated
in the Agreement are true and correct as of the date hereof. Attached herewith are the required documents supporting the above
certification. The Officer further certifies that these are prepared in accordance with Generally Accepted Accounting Principles
(GAAP) and are consistently applied from one period to the next except as explained in an accompanying letter or footnotes.

 

Please indicate compliance status by
circling Yes/No under “Complies” column.

 

 

	Reporting Covenant	 	Required	Complies
	 	 	 	 	 
	Annual financial statements (CPA Audited)	 	FYE within 90 days	Yes	No
	 	 	 	 	 
	Quarterly financial statements and Compliance Certificate	 	Prior to each Credit Extension, and monthly within 30 days	Yes	No
	 	 	 	 	 
	Monthly cash balances statement	 	Prior to each Credit Extension, and monthly within 30 days	Yes	No
	 	 	 	 	 
	10K and 10Q	 	Within 5 days of filing	Yes	No
	 	 	 	 	 
	Annual operating budget, sales projections and operating plans approved by board of directors	 	Annually no later than 30 days prior to the beginning of each fiscal year	Yes	No
	 	 	 	 	 
	
        Monthly Cash Burn (after Closing
        Date) 1:         ___________

         

        Unrestricted deposits with Bank $____________

         

        Covenant
	 	 	 	 
	
         

        At all times after the Closing Date unrestricted
        cash and cash equivalents held at accounts at the Bank must be greater than or equal to three time the Monthly Cash Burn
	 	 	Yes	No
	 	 	 	 	 
	Deposit balances with Bank	 	$	 	 	 	 
	Deposit balance outside Bank	 	$	 	 	 	 

 

1 Please attach separate
sheet showing the calculation

 

     

     

    

 

	Comments Regarding Exceptions: See Attached.	 	BANK USE ONLY
	 	 	 
	 	 	Received by:	 
	Sincerely,	 	 	AUTHORIZED SIGNER
	 	 	 
	 	 	Date:	 
	 	 	 
	 	 	Verified:	 
	SIGNATURE	 	 	AUTHORIZED SIGNER
	 	 	Date:	 
	TITLE	 	 
	 	 	Compliance Status                     Yes          No
	DATE	 	 

 

     

     

    

 

EXHIBIT D

 

SECURED PROMISSORY NOTE

(Term Loan)

 

	$[_____]	Dated:  [_____]

 

FOR VALUE RECEIVED, the undersigned, FENNEC
PHARMACEUTICALS, INC., a Delaware corporation with offices located at 68 TW Alexander Drive, Research Triangle Park, NC 27709 (“Borrower”)
HEREBY PROMISES TO PAY to the order of WESTERN ALLIANCE BANK (“Bank”) the principal amount of TWELVE MILLION
FIVE HUNDRED THOUSAND DOLLARS ($12,500,000.00) or such lesser amount as shall equal the outstanding principal balance of the Term Loan
made to Borrower by the Bank, plus interest on the aggregate unpaid principal amount of such Term Loan, at the rates and in
accordance with the terms of the Loan and Security Agreement dated January [_], 2019 by and between Borrower and the Bank (as amended,
restated, supplemented or otherwise modified from time to time, the “Loan Agreement”). If not sooner paid, the
entire principal amount and all accrued and unpaid interest hereunder shall be due and payable on the Maturity Date as set forth
in the Loan Agreement. Any capitalized term not otherwise defined herein shall have the meaning attributed to such term in the
Loan Agreement.

 

Principal, interest
and all other amounts due with respect to the Term Loan, are payable in lawful money of the United States of America to the Bank
as set forth in the Loan Agreement and this Secured Promissory Note (this “Note”). The principal amount of this
Note and the interest rate applicable thereto, and all payments made with respect thereto, shall be recorded by the Bank and, prior
to any transfer hereof, endorsed on the grid attached hereto which is part of this Note.

 

The Loan Agreement,
among other things, (a) provides for the making of a secured Term Loan by the Bank to Borrower, and (b) contains provisions
for acceleration of the maturity hereof upon the happening of certain stated events.

 

This Note may not be
prepaid except as set forth in Section 2.2 (c) and Section 2.2(d) of the Loan Agreement.

 

This Note and the obligation
of Borrower to repay the unpaid principal amount of the Term Loan, interest on the Term Loan and all other amounts due to the Bank
under the Loan Agreement is secured under the Loan Agreement.

 

Presentment for payment,
demand, notice of protest and all other demands and notices of any kind in connection with the execution, delivery, performance
and enforcement of this Note are hereby waived.

 

Borrower shall pay
all reasonable fees and expenses, including, without limitation, reasonable attorneys’ fees and costs, incurred by the Bank
in the enforcement or attempt to enforce any of Borrower’s obligations hereunder not performed when due.

 

This Note shall be
governed by, and construed and interpreted in accordance with, the internal laws of the State of California.

 

The ownership of an
interest in this Note shall be registered on a record of ownership maintained by the Bank or its agent. Notwithstanding anything
else in this Note to the contrary, the right to the principal of, and stated interest on, this Note may be transferred only if
the transfer is registered on such record of ownership and the transferee is identified as the owner of an interest in the obligation.
Borrower shall be entitled to treat the registered holder of this Note (as recorded on such record of ownership) as the owner in
fact thereof for all purposes and shall not be bound to recognize any equitable or other claim to or interest in this Note on the
part of any other person or entity.

 

[Balance of Page Intentionally
Left Blank]

 

     

     

    

 

IN WITNESS WHEREOF, Borrower has caused
this Note to be duly executed by one of its officers thereunto duly authorized on the date hereof.

 

	 	BORROWER:
	 	 	 
	 	FENNEC PHARMACEUTICALS, INC.
	 	 	 
	 	By	                          
	 	Name:	 
	 	Title:	 

 

Term Loan Note

 

     

     

    

 

LOAN INTEREST RATE AND PAYMENTS OF
PRINCIPAL

 

	 	 	Principal	 	 	 	Scheduled	 	 
	Date	 	Amount	 	Interest Rate	 	Payment Amount	 	Notation ByExhibit

Exhibit  10.1

AMENDMENT OF EXECUTIVE EMPLOYMENT AGREEMENT
THIS AMENDMENT OF EXECUTIVE EMPLOYMENT AGREEMENT is entered into as of February 4, 2019 by and between Centene Corporation, a Delaware corporation, together with its successors and assigns permitted under this Agreement (“Employer”), and Michael F. Neidorff (the “Executive”).
WHEREAS, the parties entered into that certain Executive Employment Agreement dated as of November 8, 2004, which has been amended from time to time (“Agreement”); and
WHEREAS, the parties desire to amend the Agreement in order to extend the current term of the Agreement and to make various related changes to the Agreement.
NOW THEREFORE, the parties hereto agree as follows:
1.Section 1(a) is amended so that the first sentence thereof reads as follows:

Subject to earlier termination as provided herein, Employer hereby agrees to employ and continue in its employ the Executive, and the Executive hereby accepts such employment and agrees to remain in the employ of Employer, for the period commencing on the date hereof and ending on the date of the annual shareholders meeting in 2024 (the “2024 Shareholders’ Meeting”).
2.Section 2(a) is amended to read as follows:

(a)    Executive’s Position and Title.  The Executive’s positions and titles shall continue to be Chairman and Chief Executive Officer of the Employer.  If elected to the Board of Directors (the “Board”) by the Employer’s shareholders, the Executive shall continue to be a member of, and Chairman of, the Board.  It is expected that the Executive will cease to serve as Chief Executive Officer of the Employer as of 2023 Shareholders’ Meeting, but will continue serving as Executive Chairman of the Board until the 2024 Shareholders’ Meeting, or such other date as is mutually agreed between the Executive and the Board.  Effective with the 2024 Shareholders’ Meeting (or such other date as is mutually agreed between the Executive and the Board), Executive will become Non-Executive Chairman of the Board.  While Executive serves as Executive Chairman of the Board, the Executive and the Board will mutually agree on his compensation.  While Executive serves as Executive Chairman and for five years thereafter, Executive will continue to be subject to the Company’s security policy requiring him to use Company provided aircraft for all air travel, as well as the same security measures currently applicable to Executive as Chief Executive Officer.  In addition, for the remainder of his life, Executive will continue to have an office at the Company’s headquarters and use of one full-time administrative assistant reasonably acceptable to the Executive.  Executive will also have use of a part-time administrative assistant reasonably acceptable to the Executive through December 31, 2024.
3.Section 2(b) is amended to add new sentences at the end thereof to read as follows:

As Executive Chairman of the Board, Executive shall continue to report directly to the Board, and for the avoidance of doubt shall not report to any specific member of the Board or to any member of management.  In addition to performing his duties as Executive Chairman of the Board, Executive shall assist the new Chief Executive Officer with transition matters, culture of the Company, strategy, mergers and acquisitions and community relations, and shall make himself reasonably available to assist the new Chief Executive Officer with government affairs, investor relations, investment banking relationships, and other matters reasonably requested by the Board.  It is expected that Executive’s services to the Company will be at such a level that he will incur a “Separation from Service” (as defined in Treasury Regulation Section 1.409A-1(h)) as of the 2023 Shareholders’ Meeting, and thereafter the services to be performed by Executive will be consistent with Executive having incurred a Separation from Services as of the 2023 Shareholders’ Meeting.

4.Section 3(d) is amended to add the following sentence to read as follows:

Executive shall continue to vest in all of his outstanding long term incentive awards while he serves as Chairman of the Board, regardless of whether he is serving as Executive Chairman or Non-Executive Chairman, and shall fully vest in any outstanding long term incentives (subject to any performance measures to be determined at the end of any applicable performance period) upon his ultimate termination from the Board.
5.Section 3(g) is amended to add the following sentence to read as follows:

Upon Executive ceasing to be the Executive Chairman of the Board, he may on commercially reasonable terms lease (without pilots) an aircraft that he directly or indirectly owns to the Company and the Company shall maintain and possess operational control for all flights on such aircraft when not being used by the Executive.  If the Executive uses the aircraft that is being leased to the Company for personal travel, he shall possess operational control for all flights and shall reimburse the Company on commercially reasonable terms pursuant to an aircraft support services agreement for the incremental costs of such usage.
6.Section 5(d)(ii) is amended to read as follows:

(ii)    If the Date of Termination occurs on or before the 2023 Shareholders’ Meeting, the Executive shall be entitled to receive the product of (A) one-half times (B) the sum of his (I) then-current Base Salary plus (II) the maximum amount the Executive could have earned as a Target Bonus for the year of termination if all goals and targets for payment were achieved (the “Severance Amount”), payable in cash in substantially equal installments pursuant to Employer’s payroll practices as in effect from time to time over 6 months.  The amount determined in the preceding sentence shall be payable in cash in substantially equal installments pursuant to the Employer’s payroll practices as in effect from time to time over the number of months used in the numerator in the preceding sentence.  Notwithstanding the foregoing, to the extent delay in payments under this Section 5(d)(ii) is determined to be necessary to prevent the application of and/or adverse tax consequences under Code Section 409A, then such payments shall not commence until the date which is six (6) months after the date of the Executive’s “separation from service” as that term is defined in regulations or other guidance issued under Code Section 409A;
7.The Agreement is affirmed, ratified and continued, as amended hereby.

IN WITNESS WHEREOF, the parties hereto have signed their names as of the day and year first written above.
	
					
	 
	 
	CENTENE CORPORATION

	 
	 
	 
	 
	 

	 
	 
	By:
	 
	/s/ Robert K. Ditmore

	 
	 
	Its:  Lead Director

	 
	 
	 
	 
	 

	 
	 
	/s/ Michael F. Neidorff

	 
	 
	    MICHAEL F. NEIDORFF

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