Document:

EXHIBIT 10.3
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                              REGISTRATION RIGHTS

This  constitutes  Schedule  4 to the  Stock  Exchange  Agreement  (as it may be
amended from time to time, the "Stock Exchange Agreement") dated as of April 25,
2003 between  DOBLIQUE,  INC., a company  incorporated  under the laws of Nevada
(the  "Company"),  those  persons  listed in  Schedule  1 to the Stock  Exchange
Agreement (each an Inyx Shareholder and collectively the Inyx  Shareholders) and
Inyx Pharma Limited, a company incorporated in England and Wales (Inyx).

ARTICLE 1

DEFINITIONS

Definitions.  Terms defined in the Stock  Exchange  Agreement are used herein as
therein  defined.  In addition,  the following  terms, as used herein,  have the
following meanings:

Commission means the Securities and Exchange Commission.

Holder  means a person  who owns  Registrable  Securities  and is either an Inyx
Shareholder or a transferee of an Inyx  Shareholder who has agreed in writing to
be bound by the terms of Sections  1.3 and 6.5 of the Stock  Exchange  Agreement
and this Schedule 4.

Piggyback Registration means a piggyback registration as defined in Section 2.02
of this Schedule 4.

Registrable  Securities  means (i) the Company  Shares issued under Section 1 of
the Stock Exchange Agreement,  and (ii) any additional shares of common stock of
the Company  issued in respect of the shares  referred  to in (i) in  connection
with a stock split,  stock dividend or similar event with respect to the Company
Shares. As to any particular Registrable Securities, such Registrable Securities
shall cease to be  Registrable  Securities as soon as they (i) have been sold or
otherwise  disposed of pursuant to a registration  statement that was filed with
the  Commission  and  declared  effective  under the  Securities  Act,  (ii) are
eligible  for sale  pursuant to Rule 144  without  being  subject to  applicable
volume limitations  thereunder,  (iii) have been otherwise sold,  transferred or
disposed of by a Holder to any Person that is not a Holder,  or (iv) have ceased
to be outstanding.

Rule 144 means Rule 144 (or any successor  rule of similar  effect)  promulgated
under the Securities Act.

Selling Holder means any Holder who is selling  Registrable  Securities pursuant
to a public offering registered hereunder.

Underwriter means a securities  dealer who purchases any Registrable  Securities
as principal and not as part of such dealer's market-making activities.

SECTION  1.02.  Internal  References.  Unless the context  indicates  otherwise,
references to Articles, Sections and paragraphs shall refer to the corresponding
articles,  sections and  paragraphs  in this  Schedule 4 and  references  to the
parties shall mean the parties to the Stock Exchange Agreement.

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ARTICLE 2

REGISTRATION RIGHTS

SECTION 2.01. Demand Registration.  (a) The Inyx Shareholders owing in aggregate
a majority of the Company Shares, on their own behalf and on behalf of the other
Holders,  may  make  up to two  written  requests  for  registration  under  the
Securities  Act of all or any  part of the  Registrable  Securities  held by the
Holders (each, a "Demand Registration"). Such request will specify the aggregate
number of shares of  Registrable  Securities  proposed  to be sold and will also
specify the intended  method of disposition  thereof.  A  registration  will not
count as a Demand  Registration  until it has become effective.  Should a Demand
Registration  not become  effective  due to the  failure  the Holders to perform
their  obligations  under this  Schedule 4 or the  inability  of the  requesting
Holders to reach agreement with the  Underwriters for the proposed sale on price
or other  customary terms for such  transaction,  or in the event the requesting
Holders  withdraw or do not pursue the request for the Demand  Registration  (in
each of the  foregoing  cases,  provided  that at such  time the  Company  is in
compliance in all material respects with its obligations under this Schedule 4),
then such Demand  Registration  shall be deemed to have been effected  (provided
that if the Demand  Registration does not become effective because of a material
adverse change in the condition  (financial or otherwise),  business,  assets or
results of operations  of the Company that occurs  subsequent to the date of the
written  request made by the requesting  Holders,  then the Demand  Registration
shall not be deemed to have been effected).

(b) In the event that the requesting Holders withdraw or do not pursue a request
for a Demand  Registration and, pursuant to Section 2.01(a) hereof,  such Demand
Registration  is deemed to have been  effected,  the Holders may reacquire  such
Demand  Registration  (such that the  withdrawal  or failure to pursue a request
will not count as a Demand Registration  hereunder) if the Holders reimburse the
Company  for  any and all  Registration  Expenses  incurred  by the  Company  in
connection with such request for a Demand Registration;  provided that the right
to reacquire a Demand Registration may be exercised a maximum of two times.

(c) If the Selling Holders so elect and to the extent feasible,  the offering of
such Registrable Securities pursuant to such Demand Registration shall be in the
form of an  underwritten  offering.  The Selling Holders shall have the right to
select the  managing  Underwriters  and any  additional  investment  bankers and
managers to be used in connection  with such offering,  subject to the Company's
approval, which approval shall not be unreasonably withheld.

(d) The  Selling  Holders  will inform the Company of the time and manner of any
disposition of Registrable  Securities,  and agree to reasonably  cooperate with
the Company in effecting  the  disposition  of the  Registrable  Securities in a
manner  that does not  unreasonably  disrupt the public  trading  market for the
Common Stock.

(e) The Company  will have the right to preempt any Demand  Registration  with a
primary  registration  by delivering  written  notice (within five business days
after the Company has received a request for such Demand  Registration)  of such
intention to the Selling  Holders  indicating  that the Company has identified a
specific  business need and use for the proceeds of the sale of such  securities
and the Company shall use  commercially  reasonable  efforts to effect a primary
registration within 60 days of such notice. In the ensuing primary registration,
the Holders  will have such  piggyback  registration  rights as are set forth in
Section  2.02  hereof.  Upon the  Company's  preemption  of a  requested  Demand
Registration,   such  requested   registration   will  not  count  as  a  Demand

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Registration;  provided that a Demand  Registration will not be deemed preempted
if the Holders are permitted to sell all requested securities in connection with
the ensuing primary offering by exercising their piggyback  registration  rights
as set forth in Section  2.02  hereof.  The  Company may  exercise  the right to
preempt  only twice in any  360-day  period;  provided,  that during any 360 day
period there shall be a period of at least 120 consecutive days during which the
Selling Holders may effect a Demand Registration.

(f) Subject to Section 2.03 hereof, the Company will be entitled to include in a
Demand  Registration  shares of  Common  Stock  for its own  account  or for the
account of other Persons.

(g) Notwithstanding anything to the contrary contained herein, the Company shall
be entitled to (i) postpone the filing of the Registration Statement required to
be  prepared  and  filed  by it  hereunder  or (ii)  withdraw  the  Registration
Statement  after its filing but before it has been  declared  effective,  if, in
either case, the Company in its good faith discretion  determines that there has
occurred or is  occurring a material  non-public  event which such  registration
would  interfere  with  or  which  cannot  at  such  time  be  disclosed  in the
registration  statement or if such registration statement would interfere in any
material  respect  with any  proposal  or plan by the  Company  to engage in any
financing  or any  material  acquisition  or  disposition  by the Company or any
subsidiary  thereof of the capital stock or  substantially  all of the assets of
any other Person  (other than in the ordinary  course of  business),  any tender
offer  or any  offering,  merger,  consolidation,  corporate  reorganization  or
restructuring  ("Material  Event").  In the event the filing of the Registration
Statement is postponed or withdrawn in accordance with this section 2.01(g), the
Company shall file or refile the Registration Statement within ten (10) Business
Days  after the  Company,  in its good  faith  discretion,  determines  that the
Material Event has been completed or terminated.

(h) The Company shall disclose to the Selling Holders the nature of any Material
Event for which it has  delayed  or  withdrawn  the  Registration  Statement  or
suspended  the use of the  Prospectus,  provided  the Selling  Holders  agree in
writing to keep any information so disclosed  confidential  and not complete any
trades of Company  Shares  until the Company  informs  the  Selling  Holders the
information  is considered  public  information or is no longer  material,  such
notification  to the Selling  Holders to be given promptly after the information
is considered public or is no longer material.

SECTION  2.02.  Piggyback  Registration.  If  the  Company  proposes  to  file a
registration  statement  under the Securities Act with respect to an offering of
its common stock for its own account or for the account of another Person (other
than a registration statement on Form S-4 or S-8 or pursuant to Rule 415 (or any
substitute form or rule, respectively,  that may be adopted by the Commission)),
the Company shall give written notice of such proposed  filing to the Holders at
the address set forth in the share register of the Company as soon as reasonably
practicable  (but in no event less than 10 days  before the  anticipated  filing
date),  and such notice shall offer each Holder the  opportunity  to register on
the same terms and conditions such number of shares of Registrable Securities as
such Holder may request (a "Piggyback Registration"). Each Holder will have five
business  days  after  receipt of any such  notice to notify  the  Company as to
whether it wishes to  participate  in a Piggyback  Registration;  provided  that
should a Holder fail to provide  timely notice to the Company,  such Holder will
forfeit any rights to participate in the Piggyback  Registration with respect to
such proposed offering. In the event that the registration statement is filed on
behalf of a Person other than the Company, the Company will use its best efforts
to have the  shares of  Registrable  Securities  that the  Holders  wish to sell
included in the  registration  statement.  If the Company shall determine in its
sole discretion not to register or to delay the proposed  offering,  the Company
may,  at its  election,  provide  written  notice of such  determination  to the
Holders  and (i) in the  case of a  determination  not to  effect  the  proposed
offering,  shall  thereupon  be relieved  of the  obligation  to  register  such
Registrable  Securities  in  connection  therewith,  and  (ii) in the  case of a

<PAGE>

determination  to delay a proposed  offering,  shall  thereupon  be permitted to
delay  registering such Registrable  Securities for the same period as the delay
in respect of the  proposed  offering.  As between  the  Company and the Selling
Holders,  the Company shall be entitled to select the Underwriters in connection
with any Piggyback Registration.

SECTION 2.03. Reduction of Offering.  Notwithstanding anything contained herein,
if the  managing  Underwriter  of an offering  described in Section 2.01 or 2.02
hereof states in writing that the size of the offering that Holders, the Company
and  any  other  Persons  intend  to  make is such  that  the  inclusion  of the
Registrable  Securities  would be likely to materially and adversely  affect the
price,  timing or distribution  of the offering,  then the amount of Registrable
Securities  to be offered  for the  account  of Holders  shall be reduced to the
extent necessary to reduce the total amount of securities to be included in such
offering to the amount recommended by such managing  Underwriter;  provided that
in the case of a Piggyback Registration, if securities are being offered for the
account of Persons  other than the  Company,  then the  proportion  by which the
amount of  Registrable  Securities  intended  to be offered  for the  account of
Holders  is  reduced  shall not  exceed  the  proportion  by which the amount of
securities  intended to be offered for the account of such other Persons  (other
than any Person  exercising a demand  registration  right) is reduced;  provided
further  that in the case of a Demand  Registration,  the amount of  Registrable
Securities  to be  offered  for the  account  of the  Holder  making  the Demand
Registration  shall be reduced only after the amount of securities to be offered
for the account of the Company and any other  Persons has been  reduced to zero.
In the  event  of a  reduction  pursuant  to this  Section  2.03 of  Registrable
Securities to be offered for the account of Holders, such reduction shall be pro
rata  among such  Holders  based on the number of  Registrable  Securities  each
Holder had proposed to sell.

SECTION  2.04.   Preservation  of  Rights.   The  Company  will  not  grant  any
registration  rights to third parties that contravene or are  inconsistent  with
the rights granted hereunder.

ARTICLE 3

REGISTRATION PROCEDURES

SECTION 3.01.  Filings;  Information.  In connection with a Demand  Registration
pursuant to Section  2.01  hereof,  the  Company  will use its  reasonable  best
efforts to effect the registration of such Registrable Securities as promptly as
is reasonably practicable, and in connection with any such request:

(a) The  Company  will  expeditiously  prepare  and file with the  Commission  a
registration  statement  on any form for which the Company  then  qualifies  and
which counsel for the Company shall deem  appropriate and available for the sale
of the Registrable Securities to be registered thereunder in accordance with the
intended method of distribution  thereof, and use its reasonable best efforts to
cause such filed registration  statement to become and remain effective for such
period, not to exceed 60 days, as may be reasonably necessary to effect the sale
of  such  securities;  and  provided  that  if (i)  the  effective  date  of any
registration  statement filed pursuant to a Demand  Registration would otherwise
be at least 45 calendar days, but fewer than 90 calendar days,  after the end of
the Company's  fiscal year,  and (ii) the Securities Act requires the Company to
include  audited  financials as of the end of such fiscal year,  the Company may

<PAGE>

delay the  effectiveness  of such  registration  statement for such period as is
reasonably  necessary to include  therein its audited  financial  statements for
such fiscal year.

(b) The Company will, if requested,  prior to filing such registration statement
or any amendment or supplement thereto, furnish to the Selling Holders, and each
applicable managing Underwriter,  if any, copies thereof, and thereafter furnish
to the Selling Holders and each such Underwriter,  if any, such number of copies
of such registration  statement,  amendment and supplement thereto (in each case
including all exhibits thereto and documents  incorporated by reference therein)
and the  prospectus  included in such  registration  statement  (including  each
preliminary  prospectus)  as the Selling  Holders or each such  Underwriter  may
reasonably request in order to facilitate the sale of the Registrable Securities
by the Selling Holders.

(c) After the filing of the  registration  statement,  the Company will promptly
notify  the  Selling  Holders  of any stop  order  issued  or, to the  Company's
knowledge,  threatened to be issued by the  Commission  and take all  reasonable
actions  required  to  prevent  the entry of such stop  order or to remove it if
entered.

(d) The Company will use its reasonable  best efforts to qualify the Registrable
Securities  for offer and sale under such other  securities  or blue sky laws of
such  jurisdictions  in the  United  States as the  Selling  Holders  reasonably
request; provided that the Company will not be required to (i) qualify generally
to do business in any  jurisdiction  where it would not otherwise be required to
qualify but for this paragraph  3.01(d),  (ii) subject itself to taxation in any
such  jurisdiction  or (iii)  consent to general  service of process in any such
jurisdiction.

(e) The Company will as promptly as is practicable  notify the Selling  Holders,
at any time when a prospectus relating to the sale of the Registrable Securities
is required by law to be delivered in connection with sales by an Underwriter or
dealer, of the occurrence of any event requiring the preparation of a supplement
or  amendment  to such  prospectus  so  that,  as  thereafter  delivered  to the
purchasers of such Registrable  Securities,  such prospectus will not contain an
untrue  statement of a material fact or omit to state any material fact required
to be stated therein or necessary to make the statements  therein,  in the light
of the  circumstances  under which they were made,  not  misleading and promptly
make  available  to  the  Selling  Holders  and  to the  Underwriters  any  such
supplement  or  amendment.  Upon  receipt of any notice  from the Company of the
occurrence  of any event of the kind  described in the preceding  sentence,  the
Selling  Holders will  forthwith  discontinue  the offer and sale of Registrable
Securities  pursuant to the  registration  statement  covering such  Registrable
Securities  until  receipt by the Selling  Holders and the  Underwriters  of the
copies of such  supplemented  or amended  prospectus  and, if so directed by the
Company,  the Selling Holders will deliver to the Company all copies, other than
permanent file and then in the possession of Selling Holders, of the most recent
prospectus  covering such Registrable  Securities at the time of receipt of such
notice.  In the event the Company  shall give such  notice,  the  Company  shall
extend the period during which such  registration  statement shall be maintained
effective as provided in Section 3.01(a) hereof by the number of days during the
period from and including the date of the giving of such notice to the date when
the Company shall make  available to the Selling  Holders such  supplemented  or
amended prospectus.

(f) The Company will enter into customary agreements  (including an underwriting
agreement  in  customary  form) and take such other  actions  as are  reasonably
required  in order  to  expedite  or  facilitate  the  sale of such  Registrable
Securities.

<PAGE>

(g) At the  request  of any  Underwriter  in  connection  with  an  underwritten
offering,  the Company will furnish (i) an opinion of counsel,  addressed to the
Underwriters,  covering such customary  matters as the managing  Underwriter may
reasonably  request  and (ii) a  comfort  letter  or  comfort  letters  from the
Company's  independent public accountants covering such customary matters as the
managing Underwriter may reasonably request.

(h) The Company will make generally  available to its security holders,  as soon
as reasonably practicable, an earnings statement covering a period of 12 months,
beginning  within  three  months after the  effective  date of the  registration
statement,  which  earnings  statement  shall satisfy the  provisions of Section
11(a) of the  Securities  Act and the rules and  regulations  of the  Commission
thereunder.

(i) The  Company  will use  commercially  reasonable  efforts  to cause all such
Registrable  Securities  to be listed on each  securities  exchange or quoted on
each inter-dealer  quotation system or over-the-counter  bulletin board on which
the Common Stock is then listed or quoted.

SECTION  3.02.  Selling  Holder  Information.  The Company  may require  Selling
Holders promptly to furnish in writing to the Company such information regarding
such Selling Holders, the plan of distribution of the Registrable Securities and
other information as the Company may from time to time reasonably  request or as
may be legally required in connection with any Demand  Registration or Piggyback
Registration.

SECTION 3.03.  Registration Expenses. In connection with any Demand or Piggyback
Registration,   the  Company  shall  pay  the  following  expenses  incurred  in
connection  with  such   registration   (the   "Registration   Expenses"):   (i)
registration and filing fees with the Commission and the National Association of
Securities  Dealers,  Inc., (ii) fees and expenses of compliance with securities
or blue sky laws  (including  reasonable  fees and  disbursements  of counsel in
connection with blue sky  qualifications of the Registrable  Securities),  (iii)
printing  expenses,  (iv) fees and  expenses  incurred  in  connection  with the
listing or quotation  of the  Registrable  Securities,  (v) fees and expenses of
counsel to the  Company and the  reasonable  fees and  expenses  of  independent
certified  public  accountants  for the  Company  (including  fees and  expenses
associated with the special audits or the delivery of comfort  letters) and (vi)
the  reasonable  fees and  expenses of any  additional  experts  retained by the
Company in connection with such registration.  The Selling Holders shall pay (A)
any  underwriting  fees,  discounts or commissions  attributable  to the sale of
Registrable Securities, (B) fees and expenses of counsel for the Selling Holders
and (C) any out-of-pocket expenses of the Selling Holders.

ARTICLE 4

INDEMNIFICATION AND CONTRIBUTION

SECTION 4.01.  Indemnification  by the Company.  The Company agrees to indemnify
and hold harmless each Selling Holder and its  Affiliates  and their  respective
officers,  directors,  partners,  stockholders,  members,  employees, agents and
representatives  and each Person (if any) which controls a Selling Holder within
the  meaning  of either  Section 15 of the  Securities  Act or Section 20 of the
Exchange Act, from and against any and all losses, claims, damages, liabilities,
costs and expenses (including reasonable attorneys' fees) caused by, arising out
of,  resulting  from or  related  to any  untrue  statement  or  alleged  untrue
statement  of a  material  fact  contained  in  any  registration  statement  or
prospectus relating to the Registrable Securities (as amended or supplemented if
the Company shall have furnished any  amendments or supplements  thereto) or any

<PAGE>

preliminary  prospectus,  or caused by any omission or alleged omission to state
therein a material fact  required to be stated  therein or necessary to make the
statements  therein  not  misleading,  except  insofar as such  losses,  claims,
damages  or  liabilities  are  caused  by or  contained  in or  based  upon  any
information  furnished in writing to the Company by or on behalf of such Selling
Holder or any Underwriter  expressly for use therein or by the Selling Holder or
Underwriter's  failure  to  deliver  a copy  of the  registration  statement  or
prospectus  or any  amendments  or  supplements  thereto  after the  Company has
furnished  the  Selling  Holders or  Underwriter  with  copies of the same.  The
Company also agrees to indemnify any Underwriters of the Registrable Securities,
their officers and directors and each person who controls such  Underwriters  on
substantially  the same  basis  as that of the  indemnification  of the  Selling
Holders provided in this Section 4.01.

SECTION 4.02. Indemnification by a Selling Holder. Each Selling Holder agrees to
indemnify and hold harmless the Company,  its officers and  directors,  and each
Person,  if any, which controls the Company within the meaning of either Section
15 of the Securities Act or Section 20 of the Exchange Act to the same extent as
the foregoing  indemnity from the Company to each Selling  Holder,  but only (a)
with  reference  to  information  furnished  in  writing by or on behalf of such
Selling  Holder  expressly for use in any  registration  statement or prospectus
relating to the Registrable Securities,  or any amendment or supplement thereto,
or any preliminary prospectus or (b) as a result of the Selling Holder's failure
to deliver any registration  statement or prospectus relating to the Registrable
Securities,   or  any  amendment  or  supplement  thereto,  or  any  preliminary
prospectus.  Each Selling  Holder also agrees to indemnify and hold harmless any
Underwriters  of the  Registrable  Securities,  their officers and directors and
each person who controls such  Underwriters on  substantially  the same basis as
that of the indemnification of the Company provided in this Section 4.02.

SECTION 4.03.  Conduct of  Indemnification  Proceedings.  In case any proceeding
(including any  governmental  investigation)  shall be instituted  involving any
Person in respect of which  indemnity may be sought  pursuant to Section 4.01 or
Section 4.02 hereof, such Person (the "Indemnified Party") shall promptly notify
the Person against whom such indemnity may be sought (the "Indemnifying  Party")
in writing  and the  Indemnifying  Party,  upon the  request of the  Indemnified
Party, shall retain counsel reasonably satisfactory to such Indemnified Party to
represent  such  Indemnified  Party and any  others the  Indemnifying  Party may
designate in such  proceeding and shall pay the fees and  disbursements  of such
counsel  related to such  proceeding.  In any such  proceeding,  any Indemnified
Party shall have the right to retain its own counsel,  but the fees and expenses
of such counsel shall be at the expense of such Indemnified Party unless (i) the
Indemnifying  Party and the Indemnified  Party shall have mutually agreed to the
retention  of such  counsel  or (ii) the named  parties  to any such  proceeding
(including any impleaded  parties)  include both the  Indemnified  Party and the
Indemnifying  Party and, in the written  opinion of counsel for the  Indemnified
Party, representation of both parties by the same counsel would be inappropriate
due to actual or potential  differing  interests  between them. It is understood
that the  Indemnifying  Party shall not, in  connection  with any  proceeding or
related  proceedings  in the  same  jurisdiction,  be  liable  for the  fees and
expenses of more than one separate  firm of attorneys  (in addition to any local
counsel) at any time for all such  Indemnified  Parties,  and that all such fees
and expenses  shall be reimbursed as they are incurred.  In the case of any such
separate  firm for the  Indemnified  Parties,  such firm shall be  designated in
writing by the Indemnified  Parties.  The Indemnifying Party shall not be liable
for any settlement of any proceeding  effected without its written consent,  but
if settled with such consent (not to be unreasonably withheld), or if there be a

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final judgment for the plaintiff,  the  Indemnifying  Party shall  indemnify and
hold  harmless such  Indemnified  Parties from and against any loss or liability
(to the extent stated above) by reason of such settlement or judgment.

SECTION 4.04. Contribution.  If the indemnification provided for in this Article
4 is  unavailable  to an  Indemnified  Party in respect of any  losses,  claims,
damages  or  liabilities  in  respect  of  which  indemnity  is to  be  provided
hereunder,  then each such  Indemnifying  Party,  in lieu of  indemnifying  such
Indemnified  Party,  shall to the fullest extent  permitted by law contribute to
the amount paid or payable by such Indemnified Party as a result of such losses,
claims,  damages or liabilities in such  proportion as is appropriate to reflect
the relative fault of such party in connection  with the statements or omissions
that resulted in such losses,  claims,  damages or  liabilities,  as well as any
other relevant  equitable  considerations.  The relative fault of the Company, a
Selling Holder and the  Underwriters  shall be determined by reference to, among
other things,  whether the untrue or alleged untrue statement of a material fact
or the  omission  or  alleged  omission  to state a  material  fact  relates  to
information supplied by such party and the parties' relative intent,  knowledge,
access to  information  and  opportunity to correct or prevent such statement or
omission.

The  Company  and each  Selling  Holder  agrees  that it  would  not be just and
equitable if  contribution  pursuant to this Section 4.04 were determined by pro
rata allocation  (even if the  Underwriters  were treated as one entity for such
purpose) or by any other method of allocation  that does not take account of the
equitable considerations referred to in the immediately preceding paragraph. The
amount  paid or  payable  by an  Indemnified  Party as a result  of the  losses,
claims,  damages  or  liabilities  referred  to  in  the  immediately  preceding
paragraph  shall be deemed to  include,  subject  to the  limitations  set forth
above, any legal or other expenses reasonably incurred by such Indemnified Party
in  connection  with  investigating  or  defending  any such  action  or  claim.
Notwithstanding  the  provisions  of this  Article  4, no  Underwriter  shall be
required  to  contribute  any  amount in excess of the amount by which the total
price at which the securities  underwritten  by it and distributed to the public
were  offered  to the  public  exceeds  the  amount of any  damages  which  such
Underwriter  has  otherwise  been  required  to pay by reason of such  untrue or
alleged  untrue  statement  or omission or alleged  omission,  and each  Selling
Holder shall not be required to contribute any amount in excess of the amount by
which the net proceeds of the offering (before deducting  expenses)  received by
such Selling  Holder exceeds the amount of any damages which such Selling Holder
has otherwise  been  required to pay by reason of such untrue or alleged  untrue
statement  or  omission  or alleged  omission.  No person  guilty of  fraudulent
misrepresentation  (within the meaning of Section 11(f) of the  Securities  Act)
shall be  entitled  to  contribution  from any Person who was not guilty of such
fraudulent misrepresentation.

ARTICLE 5

MISCELLANEOUS

SECTION  5.01.  Participation  in  Underwritten  Registrations.  No  Person  may
participate  in any  underwritten  registered  offering  contemplated  hereunder
unless such Person (a) agrees to sell its  securities  on the basis  provided in
any  underwriting  arrangements  approved by the Persons  entitled  hereunder to
approve such arrangements, (b) completes and executes all questionnaires, powers
of attorney,  custody  arrangements,  indemnities,  underwriting  agreements and
other  documents  reasonably  required  under  the  terms  of such  underwriting
arrangements  and this  Schedule 4 and (c)  furnishes  in writing to the Company
such  information  regarding  such  Person,  the  plan  of  distribution  of the
Registrable  Securities  and other  information  as the Company may from time to
time request or as may be legally required in connection with such registration.

<PAGE>

SECTION  5.02.  Rule 144.  The Company  covenants  that it will file any reports
required to be filed by it under the  Securities  Act and the  Exchange  Act and
that it will take such further action as the Holders may  reasonably  request to
the extent required from time to time to enable the Holders to sell  Registrable
Securities  without  registration under the Securities Act within the limitation
of the exemptions  provided by Rule 144 under the  Securities  Act, as such Rule
144 may be  amended  from  time  to  time,  or any  similar  rule or  regulation
hereafter adopted by the Commission. Upon the request of Buyer, the Company will
deliver to Buyer a written  statement  as to whether it has  complied  with such
reporting requirements.

SECTION  5.03.  Holdback  Agreements.  Each  Holder  agrees,  in the event of an
underwritten offering for the Company (whether for the account of the Company or
otherwise)  not to offer,  sell,  contract to sell or  otherwise  dispose of any
Registrable  Securities  or other Common  Stock,  including any sale pursuant to
Rule  144  under  the  Securities  Act  (except  as part  of  such  underwritten
offering),  during the 14 days prior to, and during the 180-day  period (or such
lesser period as the lead or managing  Underwriter may agree)  beginning on, the
effective date of the registration statement for such underwritten offering (or,
in the case of an offering pursuant to an effective shelf registration statement
pursuant to Rule 415, the pricing date for such underwritten offering).

SECTION 5.04. Termination. The registration rights granted under this Schedule 4
will terminate on the tenth anniversary of the Closing Date.

SECTION 5.05.  Holder  Determinations.  In the event any  determination is to be
made by the Holders or the Selling Holders as a group, such determination  shall
be made by Holders or Selling  Holders  holding a majority  in  interest  of the
Registrable Securities or the Registrable Securities being sold, respectively.EXHIBIT 10.4.1
                                                                  --------------

April 1, 2003                    Doblique, Inc.

                            EMPLOYMENT AGREEMENT WITH

                                DR. JACK KACHKAR

This Employment  Agreement  ("Agreement")  is entered into as of this 1st day of
April,  2003 (the  "Effective  Date"),  by and  between Dr.  Jack  Kachkar  (the
"Executive")  and Doblique,  Inc., a Nevada  corporation  (the  "Company" or the
"Employer"), or together the Parties.

R E C I T A L S:

Whereas,  the  Company  desires to employ  the  Executive  to  provide  personal
services to the Company,  and also wishes to provide the Executive  with certain
compensation and benefits in return for such services; and

Whereas, the Executive wishes to be employed by the Company and provide personal
services to the Company in return for certain compensation and benefits.

Now, therefore,  in consideration of the mutual promises and covenants contained
herein, it is hereby agreed by and between the Parties hereto as follows:

1. EMPLOYMENT

1.1.  GENERAL.  The Company  hereby  employs the  Executive in the  positions of
Chairman and Secretary for the Company,  and may assign other reasonable  duties
to the Executive  from time to time. The Executive will also be appointed to the
Company's  Board of  Directors  as of the  date of this  Agreement,  subject  to
subsequent ratification by the Company's majority of shareholders. The Executive
agrees to perform  and  discharge  such duties  well and  faithfully,  and to be
subject to the supervision and direction of the Board.

1.2. TIME DEVOTED TO POSITION. The Executive,  during the Employment Term, shall
devote  substantially  all of his  business  time,  attention  and skills to the
business and affairs of the Employer.

1.3.  CERTIFICATIONS.  Whenever  the  Executive  is  required  by  law,  rule or
regulation or requested by any  governmental  authority or by the Company or the
Company's  auditors  to  provide   certifications   with  respect  to  financial
statements or filings with the Securities  and Exchange  Commission or any other
governmental  authority,  the Executive shall sign such certifications as may be
reasonably  requested by such  officers,  with such  exceptions as the Executive
deems  necessary to make such  certifications  accurate and not  misleading.

<PAGE>

2. COMPENSATION AND BENEFITS

2.1. SALARY.  At all times the Executive is employed  hereunder,  Employer shall
pay to Executive,  and Executive shall accept,  as full compensation for any and
all  services  rendered and to be rendered by him during such period to Employer
in all  capacities,  including,  but not  limited to, all  services  that may be
rendered  by him  to  any of  Employer's  existing  subsidiaries,  entities  and
organizations hereafter formed,  organized or acquired by Employer,  directly or
indirectly  (each, a "Subsidiary" and  collectively,  the  "Subsidiaries"),  the
following:  (i) a base  salary at the annual  rate of  $245,000  USD, or at such
increased rate as the Board (through its  Compensation  Committee),  in its sole
discretion,  may  hereafter  from time to time  grant to  Executive,  subject to
adjustments  in  accordance  with Section 2.2 hereof (as so adjusted,  the "Base
Salary");  and (ii) any additional  bonus and the benefits set forth in Sections
2.3, 2.4 and 2.5 hereof. The Base Salary shall be payable in accordance with the
regular payroll practices of Employer applicable to senior executives, less such
deductions as shall be required to be withheld by applicable law and regulations
or otherwise.

2.2.  ADJUSTMENTS IN BASE SALARY.  On each April 1st during the Employment Term,
the Base Salary shall be increased by five percent (5%).

2.3. BONUS. Subject to Section 3.3 hereof, the Executive shall be entitled to an
annual  bonus during the  Employment  Term in such amount as  determined  by the
Board  based on such  performance  criteria as it deems  appropriate,  including
without  limitation,   the  Executive's  performance  and  Employer's  earnings,
financial  condition,  rate of return on equity and compliance  with  regulatory
requirements.  The target amount of  Executive's  annual bonus shall be at least
ten (10%)  percent  of the Base  Salary  with no cap on bonus for  reaching  and
exceeding  performance targets as set out in the Company's annual budget. At the
discretion  of the Board  (through its  Compensation  Committee),  the Executive
shall  also  be  entitled  to  additional  project  specific  bonuses  based  on
successfully completing business or commercial opportunities which are accretive
to the Company's financial performance.

2.4.  STOCK  OPTIONS.  The Executive  shall be entitled to  participate in stock
option and  similar  equity  plans of  Employer.  In  connection  herewith,  the
Executive has been granted options to purchase 750,000 shares of common stock of
the Company on terms and conditions set forth in the Stock Option Agreement with
the Company.  The  Executive  shall be entitled to any  additional  annual stock
option grants provided at the discretion of the Board.

2.5. EXECUTIVE BENEFITS

2.5.1.  EXPENSES.  Employer shall promptly  reimburse the Executive for properly
documented  expenses  that  he may  reasonably  incur  in  connection  with  the
performance of his duties  including but not limited to, expenses for such items
as  entertainment,  business  travel (all air travel shall be at least  Business

<PAGE>

Class),  hotel,  meals,  dues,  admission fees and  initiation  fees for various
clubs.  Where  appropriate the  Executive's  spouse shall be permitted to travel
with the Executive and the Executive shall be similarly  reimbursed for the cost
of his  spouse's  travel.  In the case of dues  initiation  and  other  fees for
private clubs, the amount of reimbursement under this paragraph shall not exceed
$25,000  USD  for the  year.  In  addition  to  being  reimbursed  for  properly
documented  expenses that the Executive may incur on behalf of the Company,  the
Executive  shall be reimbursed  for any  discretionary  expenses which shall not
exceed $100,000 USD in each year during the Agreement Term.

2.5.2.  EMPLOYER  PLANS.  Executive  shall be  entitled to  participate  in such
employee  benefit plans and programs as Employer may from time to time generally
offer  or  provide  to  executive  officers  of  Employer  or its  Subsidiaries,
including,  but not  limited to,  participation  in life  insurance,  health and
accident,  medical and dental plans  including any such benefit plans offered by
the Subsidiaries where applicable, and profit sharing and retirement plans.

2.5.3. VACATION.  Executive shall be entitled to four (4) weeks of paid vacation
per calendar  year,  prorated for any partial  year.  Unused  vacation days will
continue to accrue for the benefit of the Executive  and payable on  termination
of employment.

2.5.4.  TRANSPORTATION.  Employer  shall  provide  Executive  with an automobile
allowance  commensurate with his title and position together with all associated
operating  expenses and parking garage expense.  During the Employment  Term, in
accordance  with the  directives of the  Compensation  Committee,  the Executive
shall be provided with  reasonable  transportation  for business  purposes while
working at each of the Company's office or business locations.

2.5.5.  PERSONAL  FINANCIAL AND TAX CONSULTING.  The Company shall reimburse the
Executive  for  annual  expense  he  incurs  for  personal   financial  and  tax
counselling,  provided that the amount of such  reimbursement for any year shall
not exceed $20,000 USD.

2.5.6.  PERSONAL LEGAL CONSULTING.  Upon presentation of an invoice, the Company
shall  reimburse the  Executive for any legal fees and expenses  incurred in the
negotiation of this  Agreement,  provided that the amount of such  reimbursement
shall not exceed $20,000 USD.

2.5.7. LIFE INSURANCE. Employer shall obtain (PROVIDED, that Executive qualifies
on a non-rated basis) a term life insurance policy,  the premiums of which shall
be borne by  Employer  and the  death  benefits  of which  shall be  payable  to
Executive's  estate,  or as otherwise  directed by the Executive,  in the amount
equal to $1,000,000 USD.

<PAGE>

3. EMPLOYMENT TERM; TERMINATION

3.1.  EMPLOYMENT  TERM. The Executive's  employment  hereunder shall commence on
April 1, 2003 and,  except as  otherwise  provided in Section 3.2 hereof,  shall
continue  until the fifth (5th)  anniversary  of the date of this Agreement (the
"Initial Term").  Thereafter,  this Agreement shall automatically be renewed for
successive  one-year  periods  commencing on the fifth (5th)  anniversary of the
date of this Agreement (with the Initial Term and any such subsequent employment
period(s),  being referred to herein as the "Employment Term"), unless Executive
or Employer shall have provided a Notice of  Termination  (as defined in Section
3.4.2 hereof) in respect of its or his election not to renew the Employment Term
to the other  party at least  ninety (90) days prior to such  termination.  Upon
non-renewal of the  Employment  Term pursuant to this Section 3.1 or termination
pursuant to Sections 3.2.1 through 3.2.6 hereof,  inclusive,  Executive shall be
released from any duties hereunder (except as set forth in Section 4 hereof) and
the  obligations  of Employer to Executive  shall be as set forth in Section 3.3
hereof only.

3.2.  EVENTS OF  TERMINATION.  The  Employment  Term  shall  terminate  upon the
occurrence of any one or more of the following events:

3.2.1.  DEATH.  In the event of Executive's  death,  the  Employment  Term shall
terminate on the date of his death.

3.2.2.  WITHOUT CAUSE BY EXECUTIVE.  Executive may terminate the Employment Term
at any time  during  such Term for any reason  whatsoever  by giving a Notice of
Termination to Employer.  The Date of Termination pursuant to this Section 3.2.2
shall be thirty (30) days after the Notice of Termination is given.

3.2.3.  DISABILITY.  In the  event of  Executive's  Disability  (as  hereinafter
defined), Employer may, at its option, terminate the Employment Term by giving a
Notice of Termination to Executive.  The Notice of Termination shall specify the
Date of Termination, which date shall not be earlier than thirty (30) days after
the Notice of Termination is given. For purposes of this Agreement, "Disability"
means the inability of Executive for 180 days in any twelve (12) month period to
substantially  perform his duties  hereunder as a result of a physical or mental
illness, all as determined in good faith by the Board.

3.2.4.  CAUSE.  Employer may, at its option,  terminate the Employment  Term for
"Cause" based on objective factors determined in good faith by a majority of the
Board as set  forth in a Notice  of  Termination  to  Executive  specifying  the
reasons for termination and the failure of the Executive to cure the same within
thirty  (30) days after  Employer  shall  have given the Notice of  Termination;
PROVIDED, HOWEVER, that in the event the Board in good faith determines that the
underlying reasons giving rise to such  determination  cannot be cured, then the
thirty (30) day period shall not apply and the Employment  Term shall  terminate

<PAGE>

on the date the Notice of Termination is given.  For purposes of this Agreement,
"Cause" shall mean (i) Executive's conviction of, guilty or no contest plea to a
felony (ii) an act or omission by Executive in  connection  with his  employment
that  constitutes  fraud,   criminal  misconduct,   breach  of  fiduciary  duty,
dishonesty,  gross negligence,  malfeasance,  wilful misconduct or other conduct
that is materially  harmful or detrimental to Employer;  (iii) a material breach
by Executive of this Agreement and the failure of the Executive to cure the same
within thirty (30) days; (iv)  continuing  failure to perform such proper duties
as are assigned to Executive by in accordance  with this  Agreement and with law
and good business practice, other than a failure resulting from a Disability.

3.2.5. INTENTIONALLY LEFT BLANK

3.2.6. EMPLOYER'S MATERIAL BREACH.  Executive may, at his option,  terminate the
Employment  Term  upon  Employer's  material  breach of this  Agreement  and the
continuation of such breach for more than ten (10) days after written demand for
cure of such  breach is given to  Employer  by  Executive  (which  demand  shall
identify the manner in which Employer has materially  breached this  Agreement).
Employer's  material  breach of this  Agreement  shall  mean (i) the  failure of
Employer to make any payment that it is required to make  hereunder to Executive
when such payment is due or within two (2) business  days  thereafter;  (ii) the
assignment to Executive,  without Executive's express written consent, of duties
inconsistent with his positions, responsibilities and status with Employer, or a
change in Executive's reporting responsibilities, titles or offices or any plan,
act, scheme or design to constructively  terminate the Executive, or any removal
of Executive  from his positions with  Employer,  except in connection  with the
termination  of the  Employment  Term by Employer  for Cause,  without  Cause or
Disability or as a result of  Executive's  death or voluntary  resignation or by
Executive  other than  pursuant to this  Section  3.2.6;  (iii) a  reduction  by
Employer in Executive's Base Salary.

3.3.  CERTAIN  OBLIGATIONS OF EMPLOYER  FOLLOWING  TERMINATION OF THE EMPLOYMENT
TERM.  Following  termination  of the  Employment  Term under the  circumstances
described below,  Employer shall pay to Executive or his estate, as the case may
be, the  following  compensation  and  provide  the  following  benefits in full
satisfaction  and  final  settlement  of any and all  claims  and  demands  that
Executive  now  has  or  hereafter  may  have  hereunder  against  Employer.  In
connection  with  Executive's  receipt of any or all monies and  benefits  to be
received  pursuant to this Section 3.3,  Executive shall not have a duty to seek
subsequent  employment  during  the  period in which he is  receiving  severance
payments and the Severance Amount (as defined in Section 3.3.2 hereof) shall not
be reduced solely as a result of Executive's  subsequent employment by an entity
other than Employer.

<PAGE>

3.3.1.  FOR  CAUSE.  In the event  that the  Employment  Term is  terminated  by
Employer for Cause,  Employer shall pay to Executive,  in a single lump-sum,  an
amount  equal  to any  unpaid  but  earned  Base  Salary  through  the  Date  of
Termination.

3.3.2. WITHOUT CAUSE BY EMPLOYER;  MATERIAL BREACH BY EMPLOYER;  ELECTION NOT TO
RENEW BY  EMPLOYER.  In the event  that the  Employment  Term is  terminated  by
Executive  pursuant to Section 3.2.6 hereof or Employer elects not to renew this
Agreement at any time pursuant to Section 3.1 hereof,  or if such termination is
effective  at any time after a Change of Control  (as  defined in Section  3.4.1
hereof) of the  Employer,  it shall pay to  Executive,  subject  to  Executive's
continued  compliance with the terms of Section 4 hereof,  any unpaid but earned
Base Salary  through  the Date of  Termination  PLUS an amount  equal to two (2)
times  annual  Base  Salary in effect at such  applicable  time (the  "Severance
Amount").  Additionally, any bonuses that are due to the Executive shall be paid
by Employer to  Executive.  Any payments  made in  accordance  with this Section
3.3.2  shall be made in a lump sum  payment at a  convenient  date no later than
fourteen (14) days after the termination date.

3.3.3  WITHOUT CAUSE BY  EXECUTIVE;  ELECTION NOT TO RENEW BY EXECUTIVE.  In the
event that the  Employment  Term is terminated by Executive  pursuant to Section
3.2.2  hereof  or  Executive  elects  not to renew  this  Agreement  at any time
pursuant to Section 3.1 hereof,  Employer  shall pay to  Executive,  in a single
lump-sum,  an amount  equal to any  unpaid but earned  bonuses  and Base  Salary
through the Date of Termination.

3.3.4. DISABILITY. In the event that the Employment Term is terminated by reason
of Executive's  Disability pursuant to Section 3.2.3 hereof,  Employer shall pay
to  Executive,  subject  to, in the case of  Disability,  Executive's  continued
compliance with the terms of Section 4 hereof, the Severance Amount,  payable in
accordance with Section 3.3.2 hereof.

3.3.5.  POST-EMPLOYMENT  TERM  BENEFITS.  In the  event  that the  Executive  is
terminated pursuant to Sections 3.2.1 through 3.2.6 hereof, inclusive, or either
Employer or Executive elects not to renew this Agreement pursuant to Section 3.1
hereof,  Employer shall reimburse  Executive for any unpaid expenses pursuant to
Section 2.5.1 hereof and if Executive is terminated  pursuant to Sections 3.2.3,
3.2.5 or 3.2.6 hereof or Employer elects not to renew this Agreement pursuant to
Section 3.1 hereof,  Employer  shall pay, on behalf of  Executive,  for a period
equal to six (6) months from the Date of Termination  (the  "Benefits  Period"),
subject to Executive's  continued compliance with the terms of Section 4 hereof,
all life insurance,  medical,  dental, health and accident, and disability plans
and programs in which Executive was entitled to participate immediately prior to
the Date of Termination;  PROVIDED,  that Executive's continued participation is
legally  possible  under the  general  terms and  provisions  of such  plans and
programs.  In the  event  that  Executive's  participation  in any such  plan or
program  is  barred,  Employer,  at its sole  cost  and  expense  shall  use its
commercially reasonable efforts to provide Executive with benefits substantially
similar to those that  Executive  was  entitled to receive  under such plans and
programs for the remainder of the Benefits Period.

<PAGE>

3.3.6. STOCK OPTIONS

(a) If, within  twelve (12) months  following a Change of Control (as defined in
Section 3.4.1 hereof) of Employer,  the Employment Term is terminated other than
for Cause,  then  Executive  (or his estate)  shall have six (6) months from the
date of such event to exercise such stock options; PROVIDED, that the such stock
options shall not have otherwise  expired in accordance  with the terms thereof.
In connection there with, Employer agrees to use commercially reasonable efforts
to amend  Executive's  Stock Option  Agreements if necessary to  effectuate  the
provisions of this Section 3.3.6(a).

(b) In the event the Employment  Term is terminated (i) by Employer  pursuant to
Section 3.2.5 hereof and the reason for such  termination  is not related to the
performance  of Executive  in his duties with  respect to  Employer,  or (ii) by
Executive pursuant to Section 3.2.6 hereof,  then all stock options  theretofore
granted to Executive  shall  thereupon vest and Executive shall have twelve (12)
months from such date to exercise  such  options;  PROVIDED,  that the  relevant
stock  option  plan  remains  in effect and such  stock  options  shall not have
otherwise expired in accordance with the terms thereof. In connection therewith,
Employer  agrees to use  commercially  reasonable  efforts to amend  Executive's
Stock Option  Agreements  if  necessary to  effectuate  the  provisions  of this
Section 3.3.6(b).

3.4. DEFINITIONS

3.4.1.  "CHANGE OF CONTROL" DEFINED. A "Change of Control" of Employer means (i)
the approval by the stockholders of the Company of the sale, lease,  exchange or
other transfer (other than pursuant to internal  reorganization)  by the Company
of all or substantially all of its respective assets to a single purchaser or to
a group of associated  purchasers;  (ii) the first  purchase of shares of equity
securities  of the Company  pursuant to a tender offer or exchange  offer (other
than an offer by the  Company)  for at least fifty  (50%)  percent of the equity
securities of the Company; (iii) the approval by the stockholders of the Company
of an agreement  for a merger or  consolidation  in which the Company  shall not
survive as an  independent,  publicly-owned  corporation;  (iv) the  acquisition
(including by means of a merger) by a single  purchaser or a group of associated
purchasers  of  securities  of the  Company  from the Company or any third party
representing  fifty (50%)  percent or more of the  combined  voting power of the
Company's  then  outstanding  equity  securities  in one or a related  series of
transactions (other than pursuant to an internal  reorganization or transfers of
the Executive's interests).

<PAGE>

3.4.2. "NOTICE OF TERMINATION" DEFINED.  "Notice of Termination" means a written
notice that indicates the specific termination provision relied upon by Employer
or Executive and, except in the case of termination  pursuant to Sections 3.2.1,
3.2.2 or 3.2.5  hereof,  that  sets  forth in  reasonable  detail  the facts and
circumstances  claimed to provide a basis for termination of the Employment Term
under the termination provision so indicated.

3.4.3. "DATE OF TERMINATION"  DEFINED.  "Date of Termination" means such date as
the Employment  Term is expired if not renewed or terminated in accordance  with
Sections 3.1 or 3.2 hereof.

4. CONFIDENTIALITY AND NONSOLICITATION; PROPERTY RIGHTS

4.1. "CONFIDENTIAL  INFORMATION" DEFINED.  "Confidential  Information" means any
and all information  (oral or written) relating to Employer or any Subsidiary or
any entity controlling,  controlled by, or under common control with Employer or
any Subsidiary or any of their respective activities, including, information not
previously disclosed to the public or to the trade by the Company's  management,
or  otherwise in the public  domain,  with  respect to the  Company's  products,
facilities,  applications  and  methods,  trade  secrets and other  intellectual
property,  systems,  procedures,  manuals,  confidential reports,  product price
lists, customer lists,  technical information,  financial information,  business
plans,  prospects or opportunities,  but shall exclude any information which (i)
is or becomes  available to the public or is generally  known in the industry or
industries in which the Company operates other than as a result of disclosure by
the  Executive  in violation  of his  agreements  under this Section or (ii) the
Executive is required to disclose  under any  applicable  laws,  regulations  or
directives of any government agency,  tribunal or authority having  jurisdiction
in the matter or under subpoena or other process of law. The Executive  confirms
that all  restrictions  in this Section are  reasonable and valid and waives all
defences to the strict enforcement thereof.

4.2. NON-DISCLOSURE OF CONFIDENTIAL INFORMATION.  The Executive shall not at any
time  (other  than as may be  required or  appropriate  in  connection  with the
performance  by him of his  duties  hereunder),  directly  or  indirectly,  use,
communicate,  disclose or disseminate any Confidential Information in any manner
whatsoever  (except as may be required  under legal process by subpoena or other
court order).

4.3. CERTAIN ACTIVITIES.  The Executive shall not, while employed by the Company
and for a period of two (2) years following the Date of Termination, directly or
indirectly,  hire, offer to hire, entice away or in any other manner persuade or
attempt to persuade any officer,  employee,  agent,  lessor,  lessee,  licensor,
licensee or supplier of Employer or any of its  Subsidiaries  to  discontinue or
alter his or its relationship with Employer or any of its Subsidiaries.

<PAGE>

4.4. NON-COMPETITION. The Executive shall not, while employed by the Company and
for a period of three (3) years  following  the Date of  Termination,  engage or
participate,  directly or indirectly (whether as an officer, director, employee,
partner,  consultant,  shareholder,  lender or otherwise),  in any business that
manufactures,  markets or sells products that directly competes with any product
of the Employer that is significant  to the  Employer's  business based on sales
and/or  profitability of any such product as of the Date of Termination,  unless
the  Employment  Term is terminated by Employer  pursuant to Section 3.3.2 or by
the Executive  pursuant to Section 3.2.6 hereof.  Nothing  herein shall prohibit
Executive  from being a passive  owner of any  publicly-traded  class of capital
stock of any entity directly engaged in a competing business.

4.5.  PROPERTY  RIGHTS;  ASSIGNMENT OF INVENTIONS.  With respect to information,
inventions  and  discoveries  or any  interest  in any  copyright  and/or  other
property  right  developed,  made or conceived of by Executive,  either alone or
with others,  at any time during his  employment  by Employer and whether or not
within working hours,  arising out of such  employment or pertinent to any field
of business or research in which, during such employment, Employer is engaged or
(if such is known to or  ascertainable  by Executive) is  considering  engaging,
Executive hereby agrees:

(a) that all such information, inventions and discoveries or any interest in any
copyright  and/or other property  right,  whether or not patented or patentable,
shall be and remain the exclusive property of the Employer;

(b) to disclose  promptly to an authorized  representative  of Employer all such
information,  inventions and discoveries or any copyright  and/or other property
right and all information in Executive's  possession as to possible applications
and uses thereof;

(c) not to file  any  patent  application  relating  to any  such  invention  or
discovery  except with the prior  written  consent of an  authorized  officer of
Employer (other than Executive);

(d) that Executive  hereby waives and releases any and all rights  Executive may
have in and to such information,  inventions and discoveries, and hereby assigns
to Executive and/or its nominees all of Executive's right, title and interest in
them,  and all  Executive's  right,  title and  interest in any  patent,  patent
application,  copyright or other property right based thereon.  Executive hereby
irrevocably  designates  and appoints  Employer and each of its duly  authorized
officers and agents as his agent and  attorney-in-fact to act for him and on his
behalf and in his stead to  execute  and file any  document  and to do all other
lawfully permitted acts to further the prosecution,  issuance and enforcement of
any such patent, patent application,  copyright or other property right with the
same force and effect as if executed and delivered by Executive; and

<PAGE>

(e) at the request of Employer,  and without  expense to  Executive,  to execute
such  documents  and perform  such other acts as  Employer  deems  necessary  or
appropriate, for Employer to obtain patents on such inventions in a jurisdiction
or  jurisdictions  designated  by  Employer,  and to assign to  Employer  or its
designee  such  inventions  and any  and all  patent  applications  and  patents
relating thereto.

4.6.  INJUNCTIVE  RELIEF.  The  parties  hereby  acknowledge  and agree that (a)
Employer  will be  irreparably  injured in the event of a breach by Executive of
any of his obligations under this Section 4; (b) monetary damages will not be an
adequate remedy for any such breach; (c) Employer will be entitled to injunctive
relief,  in addition to any other remedy which it may have,  in the event of any
such breach; and (d) the existence of any claims that Executive may have against
Employer,  whether under this  Agreement or otherwise,  will not be a defence to
the enforcement by Employer of any of its rights under this Section 4.

4.7.  NON-EXCLUSIVITY AND SURVIVAL.  The covenants of the Executive contained in
this  Section 4 are in  addition  to, and not in lieu of, any  obligations  that
Executive  may have with  respect  to the  subject  matter  hereof,  whether  by
contract,  as a  matter  of law or  otherwise,  and  such  covenants  and  their
enforceability  shall survive any  termination of the Employment  Term by either
party and any investigation  made with respect to the breach thereof by Employer
at any time.

5. MISCELLANEOUS PROVISIONS.

5.1.  SEVERABILITY.  If, in any  jurisdiction,  any term or provision  hereof is
determined  to  be  invalid  or  unenforceable,  (a)  the  remaining  terms  and
provisions   hereof   shall  be   unimpaired;   (b)  any  such   invalidity   or
unenforceability   in  any   jurisdiction   shall  not   invalidate   or  render
unenforceable such provision in any other  jurisdiction;  and (c) the invalid or
unenforceable  term or provision  shall, for purposes of such  jurisdiction,  be
deemed  replaced by a term or provision that is valid and  enforceable  and that
comes closest to expressing the intention of the invalid or  unenforceable  term
or provision.

5.2.  EXECUTION IN  COUNTERPARTS.  This Agreement may be executed in one or more
counterparts, and by the different parties hereto in separate counterparts, each
of which shall be deemed to be an original but all of which taken together shall
constitute one and the same agreement (and all signatures need not appear on any
one  counterpart),  and this Agreement  shall become  effective when one or more
counterparts has been signed by each of the parties hereto and delivered to each
of the other parties hereto.

5.3. NOTICES. All notices,  requests, demands and other communications hereunder
shall be in writing and shall be deemed duly given upon receipt  when  delivered

<PAGE>

by hand, overnight delivery or telecopy (with confirmed delivery),  or three (3)
business days after  posting,  when delivered by registered or certified mail or
private courier service, postage prepaid, return receipt requested, as follows:

If to Employer, to:

Doblique, Inc.
801 Brickell 9th. Floor,
Miami, FL 33131
Attention:  Vice President - Finance and Treasurer
Telecopy No.: (305) 789-6641

If to Executive, to:

Dr. Jack Kachkar
Unit #1210, 445 Grand Bay Drive
Key Biscayne, Florida 33149
Telecopy No.: (305) 365 3963

or to such other  address(es) as a party hereto shall have  designated by notice
in writing to the other parties hereto.

5.4. AMENDMENT. No provision of this Agreement may be modified, amended, waived,
or discharged in any manner except by a written instrument  executed by both the
Employer and the Executive.

5.5. ENTIRE AGREEMENT. This Agreement and, with respect to Section 3.3.6 hereof,
Executive's  Stock Option  Agreements  and the  governing  stock  option  plans,
constitute  the entire  agreement  of the  parties  hereto  with  respect to the
subject matter hereof,  and supersede all prior agreements and understandings of
the  parties  hereto,  oral or  written.  In the event of any  conflict  between
Section 3.3.6 hereof and Executive's  Stock Option  Agreements and the governing
stock option plans, Section 3.3.6 shall govern.

5.6.  APPLICABLE  LAW.  This  Agreement  shall be governed by and  construed  in
accordance  with the laws of the State of Florida  applicable to contracts  made
and to be wholly performed therein.

5.7. INTENTIONALLY LEFT BLANK.

5.8.  HEADINGS.  The  headings  contained  herein  are for the sole  purpose  of
convenience  of reference,  and shall not in any way limit or affect the meaning
or interpretation of any of the terms or provisions of this Agreement.

<PAGE>

5.9. BINDING EFFECT;  SUCCESSORS AND ASSIGNS. The Executive may not delegate any
of his duties or assign his rights hereunder.  This Agreement shall inure to the
benefit of, and be binding upon, the parties hereto and their respective  heirs,
legal representatives,  successors and permitted assigns. Employer shall require
any  successor  (whether  direct or indirect  and whether by  purchase,  merger,
consolidation or otherwise) to all or  substantially  all of the business and/or
assets  of  Employer,   by  an  agreement  in  form  and  substance   reasonably
satisfactory  to  Executive,  to  expressly  assume  and agree to  perform  this
Agreement  in the same  manner and to the same  extent  that  Employer  would be
required to perform if no such succession had taken place.

5.10. WAIVER,  ETC. The failure of either of the parties hereto to, at any time,
enforce any of the provisions of this Agreement shall not be deemed or construed
to be a waiver of any such  provision,  nor to in any way affect the validity of
this  Agreement  or any  provision  hereof or the right of either of the parties
hereto  thereafter  to enforce each and every  provision of this  Agreement.  No
waiver  of any  breach  of any of the  provisions  of this  Agreement  shall  be
effective unless set forth in a written instrument executed by the party against
whom or which  enforcement  of such waiver is sought,  and no waiver of any such
breach shall be  construed  or deemed to be a waiver of any other or  subsequent
breach.

5.11. CAPACITY,  ETC. Executive and Employer hereby represent and warrant to the
other  that,  as the case may be:  (a) he or it has full  power,  authority  and
capacity  to execute  and  deliver  this  Agreement,  and to perform  his or its
obligations  hereunder;  (b) such execution,  delivery and performance shall not
(and with the giving of notice or lapse of time or both would not) result in the
breach of any agreements or other obligations to which he or it is a party or he
or it is otherwise bound; and (c) this Agreement is his or its valid and binding
obligation in accordance with its terms.

5.12.  ARBITRATION.  Any dispute or  controversy  arising under or in connection
with this Agreement  shall be settled  exclusively  in arbitration  conducted in
Miami,  Florida  in  accordance  with  the  rules  of the  American  Arbitration
Association then in effect. Judgment may be entered on the arbitrator's award in
any court having  jurisdiction.  Punitive  damages shall not be awarded.  In any
arbitration proceeding, the party determined to be the prevailing party shall be
entitled to receive,  in addition to any other award,  its  attorneys'  fees and
expenses of the proceeding.

                            [SIGNATURE PAGE FOLLOWS]

<PAGE>

         IN WITNESS  WHEREOF,  this Agreement has been executed and delivered by
the parties hereto as of the date first above written.

DOBLIQUE, INC.

By:

/s/ Rima Goldshmidt
----------------------------
Name:  Rima Goldshmidt
Title: Vice President

 /S/ Jack Kachkar
----------------------------
Dr. Jack Kachkar MD

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