Document:

Exhibit 10.13

 

THIS PROMISSORY NOTE (“NOTE”) HAS NOT BEEN REGISTERED UNDER THE SECURITIES
ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”). THIS NOTE HAS BEEN ACQUIRED FOR INVESTMENT ONLY AND
MAY NOT BE SOLD, TRANSFERRED OR ASSIGNED IN THE ABSENCE OF REGISTRATION OF THE RESALE THEREOF UNDER THE SECURITIES ACT OR AN OPINION
OF COUNSEL REASONABLY SATISFACTORY IN FORM, SCOPE AND SUBSTANCE TO THE ISSUER THAT SUCH REGISTRATION IS NOT REQUIRED.

 

PROMISSORY NOTE

 

	Principal Amount: $1,087,031	Issuance Date: March 15, 2019

 

KBL Merger Corp. IV,
a Delaware corporation (“Maker”), promises to pay to the order of KBL IV Sponsor LLC or its successors or assigns
(“Payee”), the principal sum of One Million Eighty-Seven Thousand Thirty-One Dollars ($1,087,031) in lawful money
of the United States of America, on the terms and conditions described below.

 

1. Repayment. The
principal balance of this Note shall be due and payable on the earlier of (i) the consummation of Maker’s initial business
combination (the “Business Combination”) (as described in the prospectus contained in Maker’s registration
statement on Form S-1 filed with the Securities and. Exchange Commission in connection with Maker’s initial public offering
(the “IPO”)) or (ii) the liquidation of Maker. Payee understands that if a Business Combination is not consummated,
this Note will not be repaid except to the extent that Maker has funds available to it outside of its Trust Account (as defined
below) established in connection with its IPO. The principal balance may be prepaid at any time, at the election of Maker. All
payments on this Note (except to the extent that the principal is converted pursuant to Section 15 below) shall be made by check
or wire transfer of immediately available funds or as otherwise agreed by Payee to such account as Payee may from time to time
designate by written notice in accordance with the provisions of this Note.

 

2. Interest.
This Note shall be non-interest bearing.

 

3. Application
of Payments. All payments received by Payee pursuant to this Note shall be applied first to the payment in full of any costs
incurred in the collection of any sum due under this Note, including without limitation reasonable attorneys’ fees, then to the
payment in full of any late charges and finally to the reduction of the unpaid principal balance of this Note.

 

4. Events
of Default. The following shall constitute an event of default (“Event of Default”):

 

(a) Failure
to Make Required Payments. Failure by Maker to pay the principal amount due pursuant to this Note within five (5) business
days following the date when due.

 

(b) Voluntary
Bankruptcy, Etc. The commencement by Maker of a voluntary case under the Federal Bankruptcy Code, as now constituted or hereafter
amended, or any other applicable bankruptcy, insolvency, reorganization, rehabilitation or other similar law (“Bankruptcy
Laws”), or the consent by it to the appointment of or taking possession by a receiver, liquidator, assignee, trustee,
custodian, sequestrator (or other similar official) of Maker or for any substantial part of its property, or the making by it of
any assignment for the benefit of creditors, or the failure of Maker generally to pay its debts as such debts become due, or the
taking of corporate action by Maker in furtherance of any of the foregoing.

 

     

     

    

 

(c) Involuntary
Bankruptcy, Etc. The entry of a decree or order for relief by a court having jurisdiction in the premises in
respect of Maker in an involuntary case under any applicable Bankruptcy Laws, or appointing a receiver, liquidator, assignee,
custodian, trustee, sequestrator (or similar official) of Maker or for any substantial part of its property, or ordering the
winding-up or liquidation of its affairs, and the continuance of any such decree or order unstayed and in effect for a period
of 60 consecutive days.

 

5. Remedies.

 

(a) Upon
the occurrence of an Event of Default specified in Section 4(a) hereof, Payee may, by written notice to Maker, declare this Note
to be due immediately and payable, whereupon the unpaid principal amount of this Note and all other amounts payable hereunder shall
become immediately due and payable without presentment, demand, protest or other notice of any kind, all of which are hereby expressly
waived, anything contained herein or in the documents evidencing the same to the contrary notwithstanding.

 

(b) Upon
the occurrence of an Event of Default specified in Sections 4(b) and 4(c) hereof, the unpaid principal balance of this Note and
all other amounts payable hereunder shall automatically and immediately become due and payable, in all cases without any action
on the part of Payee.

 

6. Waivers. Maker and all endorsers and
guarantors of, and sureties for, this Note waive presentment for payment, demand, notice of dishonor, protest, and notice of protest
with regard to this Note, all errors, defects and imperfections in any proceedings instituted by Payee under the terms of this
Note, and all benefits that might accrue to Maker by virtue of any present or future laws exempting any property, real or personal,
or any part of the proceeds arising from any sale of any such property, from attachment, levy or sale under execution, or providing
for any stay of execution, exemption from civil process, or extension of time for payment; and Maker agrees that any real or personal
property that may be levied upon pursuant to a judgment obtained by virtue hereof, on any writ of execution issued hereon, may
be sold upon any such writ in whole or in part in any order desired by Payee.

 

7.
Unconditional Liability. Maker hereby waives all notices in connection with the delivery, acceptance, performance,
default, or enforcement of the payment of this Note, and agrees that its liability shall be unconditional, without regard to
the liability of any other party, and shall not be affected in any manner by any indulgence, extension of time, renewal,
waiver or modification granted or consented to by Payee, and consents to any and all extensions of time, renewals, waivers,
or modifications that may be granted by Payee with respect to the payment or other provisions of this Note, and agrees that
additional makers, endorsers, guarantors, or sureties may become parties hereto without notice to Maker or affecting Maker’s
liability hereunder.

 

8. Notices. Any notice called for
hereunder shall be deemed properly given if (i) sent by certified mail, return receipt requested, (ii) personally delivered,
(iii) dispatched by any form of private or governmental express mail or delivery service providing receipted delivery, (iv)
sent by facsimile or (v) sent by e-mail, to the following addresses or to such other address as either party may designate by
notice in accordance with this Section:

 

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	If to Maker, to:	 	with a copy (which will not constitute notice) to:
	 	 	 
	KBL Merger Corp. IV	 	Ellenoff Grossman & Schole LLP
	150 West 56th Street, Suite 5901	 	1345 Avenue of the Americas, 11th Floor
	New York, NY 10019	 	New York, New York 10105
	Attn: Marlene Krauss M.D., CEO	 	Attn: 	Stuart Neuhauser, Esq.
	Email: mkrauss@kblvc.com	 	 	Matthew A. Gray, Esq.
	 	 	Facsimile No.: (212) 370-7889
	 	 	Telephone No.: (212) 370-1300
	 	 	Email:   	sneuhauser@egsllp.com
	 	 	 	mgray@egsllp.com
	 	 	 

 

	If to Payee, to:	 	with
    a copy (which will not constitute notice) to:
	 	 	 
	KBL Sponsor IV LLC	 	Ellenoff
    Grossman & Schole LLP
	150 West 56th Street, Suite 5901	 	1345
    Avenue of the Americas, 11th Floor
	New York, NY 10019	 	New
    York, New York 10105
	Attn: Marlene Krauss M.D.,
    Managing Member	 	Attn:
    	Stuart
    Neuhauser, Esq.
	Email: mkrauss@kblvc.com	 	 	Matthew A. Gray,
    Esq.
		 	Facsimile
    No.: (212) 370-7889
	 	 	Telephone
    No.: (212) 370-1300
	 	 	Email:  	sneuhauser@egsllp.com
	 	 	 	mgray@egsllp.com
	 	 	 

 

Notice shall be deemed
given on the earlier of (i) actual receipt by the receiving party, (ii) the date shown on a facsimile transmission confirmation,
(iii) the date on which an e-mail transmission was received by the receiving party’s on-line access provider (iv) the date reflected
on a signed delivery receipt, or (vi) two (2) business days following tender of delivery or dispatch by express mail or delivery
service.

 

9. Governing
Law; Venue, Jury Trial Waiver. This Note shall be construed and enforced in accordance with the laws of the State of New York,
without regard to the conflict of laws provisions thereof. Any legal suit, action or proceeding arising out of or relating to this
Note shall be instituted exclusively in the state or federal courts of the State of New York (and any appellate courts thereof).
EACH PARTY HERETO HEREBY IRREVOCABLY WAIVES ANY AND ALL RIGHT TO TRIAL BY JURY IN ANY LEGAL PROCEEDING ARISING OUT OF OR RELATED
TO THIS NOTE OR ANY OBLIGATIONS HEREUNDER.

 

10. Severability.
Any provision contained in this Note which is prohibited or unenforceable in any jurisdiction shall, as to such jurisdiction,
be ineffective to the extent of such prohibition or unenforceability without invalidating the remaining provisions hereof, and
any such prohibition or unenforceability in any jurisdiction shall not invalidate or render unenforceable such provision in any
other jurisdiction.

 

11.
Trust Waiver. Notwithstanding anything herein to the contrary, Payee hereby waives any and all right, title, interest or
claim of any kind (a “Claim”) in or to any distribution of or from the trust account (the “Trust
Account”) established by Maker in which the proceeds of the IPO (including without limitation overallotment
securities sold by Maker’s underwriter) and the proceeds of the sale of the units issued in the private placement that
occurred in connection with the IPO, as described in greater detail in the registration statement and prospectus filed in
connection with the IPO, were deposited, and hereby agrees not to seek recourse, reimbursement, payment or satisfaction for
any Claim against the Trust Account or distributions therefrom to Maker’s public stockholders for any reason whatsoever;
provided, however, that, subject to Section 15 below, upon the consummation of the Business
Combination, Maker shall repay the principal balance of this Note out of the proceeds released to Maker from the Trust
Account.

 

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12. Entire
Agreement; Amendment; Waiver. This Note constitutes the entire agreement between the parties with respect to the subject matter
hereof and referenced herein, and supersedes and terminates any prior agreements between the parties (written or oral) with respect
to the subject matter hereof. Any amendment or modification to, or waiver of any provision of, this Note may be made with, and
only with, the written consent of Maker and Payee.

 

13. Assignment.
No assignment or transfer of this Note or any rights or obligations hereunder may be made by any party hereto (by operation
of law or otherwise) without the prior written consent of the other party hereto and any attempted assignment without the required
consent shall be void; provided, however, that the foregoing shall not apply to an affiliate of Payee who agrees to be bound
to the terms of this Note.

 

14. Miscellaneous.
Each right, power and remedy of Payee provided for in this Note or now or hereafter existing at law or in equity or by statute
or otherwise shall be cumulative and concurrent and shall be in addition to every other such right, power or remedy. This Note
may be executed in multiple counterparts, including without limitation by facsimile, pdf or other electronic document transmission,
each of which shall be deemed an original and all of which together shall constitute one and the same instrument. When a reference
is made in this Note to a Section, such reference shall be to a Section of or to this Note unless otherwise indicated. Unless the
context requires otherwise, the terms “hereof,” “herein,” “hereby,” “hereto” and derivative
or similar words in this Note refer to this entire Note. Unless the context requires otherwise, words in this Note using the singular
or plural number also include the plural or singular number, respectively, and the use of any gender herein shall be deemed to
include the other genders. References in this Note to “dollars”, “Dollars” or “$” are to U.S. dollars.
This Note was prepared jointly by the parties and no rule that it be construed against the drafter will have any application in
its construction or interpretation. For purposes of this Note, the term “business day” shall mean any day that is not
a Saturday, Sunday or any other day on which banks are required or authorized by law to be closed in New York, New York.

 

15. Conversion.

 

(a) Notwithstanding
anything contained in this Note to the contrary, at Payee’s sole option, at any time prior to payment in full of the principal
balance of this Note, Payee may elect to convert all or any portion of the unpaid principal balance of this Note (subject to the
last sentence hereof) into that number of units, each unit consisting of one share of common stock of Maker, one right to receive
one-tenth (1/10th) of one share of common stock of Maker upon the consummation of a Business Combination, and one warrant
exercisable for one-half (1/2) of a share of common stock of Maker (the “Conversion Units”) equal to: (x) the
portion of the principal amount of this Note being converted pursuant to this Section 15, divided by (y) $10.00, rounded up to
the nearest whole number of units. The Conversion Units shall be identical to the units issued by Maker to Payee in the private
placement that was consummated in connection with the IPO. The Conversion Units and their underlying securities, and any other
equity security of Maker issued or issuable with respect to the foregoing by way of a stock dividend or stock split or in connection
with a combination of shares, recapitalization, amalgamation, consolidation or reorganization, shall be entitled to the registration
rights set forth in Section 16 hereof. Notwithstanding the foregoing, the maximum amount of principal that the Payee may convert
into Conversion Units under this Section 15 may not exceed One Million U.S. Dollars ($1,000,000) in the aggregate, and any additional
principal balance in excess of the amounts converted into Conversion Units shall be paid in accordance with Section 1.

 

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(b) Upon
any complete or partial conversion of the principal amount of this Note, (i) such principal amount shall be so converted and such
converted portion of this Note shall become fully paid and satisfied, (ii) Payee shall surrender and deliver this Note, duly endorsed,
to Maker or such other address which Maker shall designate against delivery of the Conversion Units, (iii) Maker shall promptly
deliver a new duly executed Note to Payee in the principal amount that remains outstanding, if any, after any such conversion and
(iv) in exchange for all or any portion of the surrendered Note, Maker shall, at the direction of Payee, deliver to Payee (or its
members or their respective affiliates as designated by Payee) (Payee or such other persons, the “Holders”) the
Conversion Units, which shall bear such legends as are required, in the opinion of counsel to Maker or by any other agreement between
Maker and Payee and applicable state and federal securities laws.

 

(c) The
Holders shall pay any and all issue and other taxes that may be payable with respect to any issue or delivery of the Conversion
Units upon conversion of this Note pursuant hereto; provided, however, that the Holders shall not be obligated to pay any transfer
taxes resulting from any transfer requested by the Holders in connection with any such conversion.

 

(d) The
Conversion Units shall not be issued upon conversion of this Note unless such issuance and such conversion comply with all applicable
provisions of law.

 

16. Registration Rights. Reference is
made to that certain Registration Rights Agreement between Maker and the parties thereto, dated as of June 1, 2017 (the “Registration
Rights Agreement”). All capitalized terms used in this Section 16 shall have the same meanings ascribed to them in
the Registration Rights Agreement. The Holders shall have the rights and obligations with respect to the Conversion Units and
their underlying securities as the “Holders” under the Registration Rights Agreement with respect to the Private
Placement Shares, Private Placement Rights and Private Placement Warrants, except that they separately shall be entitled to
one separate Demand Registration with respect to the Conversion Units and their underlying securities, which shall be subject
to the same provisions as set forth in Section 2.1 of the Registration Rights Agreement.

 

[Signature Page Follows]

 

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IN WITNESS WHEREOF,
Maker, intending to be legally bound hereby, has caused this Note to be duly executed by the undersigned as of the day and
year first above written.

 

	 	KBL MERGER CORP. IV
	 	 
	 	By:	 /s/ Marlene Krauss, M.D.
	 	Name:	Marlene Krauss, M.D.
	 	Title:	Chief Executive Officer

 

Acknowledged and agreed,
effective as of the date first set forth above:

 

	KBL SPONSOR IV LLC	 
	 	 
	By:	 /s/ Marlene Krauss, M.D.	 
	Name:	Marlene Krauss, M.D.	 
	Title:	Managing MemberExhibit 10.14

 

PROMISSORY NOTE

 

	Principal: $250,000	August 21, 2019

 

KBL Merger Corp.
IV, a Delaware corporation (“Maker”), promises to pay to the order of CannBioRx Life Sciences Corp.,
a Delaware corporation (“Payee”), the principal sum of $250,000 (the “Principal Amount”)
in lawful money of the United States of America, on the terms and conditions described below. Capitalized terms used but not
defined in this promissory note (this “Note”) shall have the meanings ascribed to them in that certain
Business Combination Agreement (the “Business Combination Agreement”) by and among Maker, Payee, Katexco
Pharmaceuticals Corp., a British Columbia corporation, CannBioRex Pharmaceuticals Corp., a British Columbia corporation, 180 Therapeutics
L.P., a Delaware limited partnership, KBL Merger Sub, Inc., a Delaware corporation, and Lawrence Pemble, in his capacity as the
stockholder representative.

 

1. Principal.
The principal balance of this Note shall be payable on the earlier of (i) consummation of Maker’s Business Combination (whether
pursuant to the Business Combination Agreement or otherwise) and (ii) the liquidation of Maker in the event it does not consummate
a Business Combination. Maker hereby agrees that upon the consummation of an Alternative Business Combination pursuant to Section
7.3(a)(i) of the Business Combination Agreement, in addition to the repayment of the principal amount of this Note in accordance
with this Section 1, it will use its reasonable efforts to cause the Sponsor to comply with its obligations under Section 7(a)(i)
of the Business Combination Agreement to cause the Founder Shares Escrow Agent to transfer to Tyche Capital LLC a number of Escrowed
Founder Shares equal in value to three times the amount of the Covered Expense Loans, with each Escrowed Founder Share valued at
the Per Share Redemption Price (subject to equitable adjustment for stock splits, stock dividends, share exchanges, etc.).

 

2. Required
Prepayment. In the event that the Business Combination has not been consummated by the later of (a) the third Automatic Extension
or (b) the Additional Extension, as applicable, then promptly (but in any event within three Business Days) thereafter, Maker will
use any remaining funds in escrow with the Expense Escrow Agent to prepay the balance of this Note.

 

3. Interest.
No interest shall accrue on the unpaid principal balance of this Note.

 

4. Application
of Payments. All payments shall be applied first to payment in full of any costs incurred in the collection of any sum due
under this Note, including (without limitation) reasonable attorneys’ fees, then to the payment in full of any late charges and
finally to the reduction of the unpaid principal balance of this Note.

 

5. Events
of Default. The following shall constitute Events of Default:

 

(a) Failure
to Make Required Payments. Failure by Maker to pay the principal of this Note within five (5) Business Days following the date
when due.

 

(b) Voluntary
Bankruptcy, Etc. The commencement by Maker of a voluntary case under the Federal Bankruptcy Code, as now constituted or hereafter
amended, or any other applicable federal or state bankruptcy, insolvency, reorganization, rehabilitation or other similar law,
or the consent by it to the appointment of or taking possession by a receiver, liquidator, assignee, trustee, custodian, sequestrator
(or other similar official) of Maker or for any substantial part of its property, or the making by it of any assignment for the
benefit of creditors, or the failure of Maker generally to pay its debts as such debts become due.

 

     

     

    

 

(c) Involuntary
Bankruptcy, Etc. The entry of a decree or order for relief by a court having jurisdiction in the premises in respect of Maker
in an involuntary case under the Federal Bankruptcy Code, as now or hereafter constituted, or any other applicable federal or state
bankruptcy, insolvency or other similar law, or appointing a receiver, liquidator, assignee, custodian, trustee, sequestrator (or
similar official) of Maker or for any substantial part of its property, or ordering the winding-up or liquidation of its affairs,
and the continuance of any such decree or order unstayed and in effect for a period of 60 consecutive days.

 

6. Remedies.

 

(a)
Upon the occurrence of an Event of Default specified in Section 5(a), Payee may, by written notice to Maker, declare this
Note to be due and payable, whereupon the principal amount of this Note, and all other amounts payable thereunder, shall become
immediately due and payable without presentment, demand, protest or other notice of any kind, all of which are hereby expressly
waived, anything contained herein or in the documents evidencing the same to the contrary notwithstanding.

 

(b) Upon
the occurrence of an Event of Default specified in Sections 5(b) and 5(c), the unpaid principal balance of, and all other sums
payable with regard to, this Note shall automatically and immediately become due and payable, in all cases without any action on
the part of Payee.

 

7. Waivers.
Maker and any endorsers and guarantors of, and sureties for, this Note waive presentment for payment, demand, notice of dishonor,
protest, and notice of protest with regard to the Note, all errors, defects and imperfections in any proceedings instituted by
Payee under the terms of this Note, and all benefits that might accrue to Maker by virtue of any present or future laws exempting
any property, real or personal, or any part of the proceeds arising from any sale of any such property, from attachment, levy or
sale under execution, or providing for any stay of execution, exemption from civil process, or extension of time for payment; and
Maker agrees that any real estate that may be levied upon pursuant to a judgment obtained by virtue hereof, on any writ of execution
issued hereon, may be sold upon any such writ in whole or in part in any order desired by Payee.

 

8. Unconditional
Liability. Maker hereby waives all notices in connection with the delivery, acceptance, performance, default, or enforcement
of the payment of this Note, and agrees that its liability shall be unconditional, without regard to the liability of any other
party, and shall not be affected in any manner by any indulgence, extension of time, renewal, waiver or modification granted or
consented to by Payee, and consents to any and all extensions of time, renewals, waivers, or modifications that may be granted
by Payee with respect to the payment or other provisions of this Note, and agrees that any additional makers, endorsers, guarantors,
or sureties may become parties hereto without notice to them or affecting their liability hereunder.

 

9. Notices.
Any notice called for hereunder shall be delivered in the manner set forth in Section 9.3 of the Business Combination Agreement.

 

10. Construction;
Venue. This Note shall be construed and enforced in accordance with the domestic, internal law, but not the law of conflict
of laws, of the State of New York. Any action, claim, suit or other legal proceeding relating to this Note shall be brought exclusively
in the state or federal courts located in New York County, State of New York (or any appellate courts therefrom). The parties expressly
waive any objection based on personal jurisdiction, venue or forum non conveniens.

 

11. Severability.
Any provision contained in this Note which is prohibited or unenforceable in any jurisdiction shall, as to such
jurisdiction, be ineffective to the extent of such prohibition or unenforceability without invalidating the remaining
provisions hereof, and any such prohibition or unenforceability in any jurisdiction shall not invalidate or render
unenforceable such provision in any other jurisdiction.

 

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12. Miscellaneous.
This Note will not be assignable or transferable by either Maker or Payee without the prior written consent of the other, and any
purported assignment or transfer without such consent shall be null and void ab initio. This Note, together with the Business Combination
Agreement, constitutes the full and entire understanding and agreement between the parties with regard to the subject matter hereof
and supersedes all prior understandings or agreements with respect thereto. No amendments or modifications of or changes to this
Note or waiver of the terms and conditions hereof will be binding upon Maker or Payee, unless approved in writing and signed by
both Maker and Payee.

 

13. Trust
Fund Waiver. Payee hereby acknowledges that the waiver against Maker’s Trust Account (and distributions therefrom) contained
in Section 9.18 of the Business Combination Agreement continues in full force and effect and will apply to this Note and Maker’s
obligations hereunder.

 

[Signature Page Follows]

 

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IN WITNESS
WHEREOF, Maker, intending to be legally bound hereby, has caused this Note to be duly executed the day and year first above
written.

 

	 	KBL MERGER CORP. IV
	 	 
	 	By:	 /s/ Marlene Krauss, M.D.
	 	Name:  	Marlene Krauss, M.D.
	 	Title:	Chief Executive Officer

 

Acknowledged and agreed effective as of the day
and year first written above: 

  

	CANNBIORX LIFE SCIENCES CORP.	 
	 	 
	By:	 /s/ Prof. Sir Marc Feldmann	 
	Name:  	 Prof. Sir Marc Feldmann	 
	Title:	Chairman	 

 

[Signature
Page to Operating Expenses Promissory Note]

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