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	**
	Certain information in these exhibits has been omitted and will be filed separately with the Securities and Exchange Commission pursuant to a confidential
treatment request under 17 C.F.R. Sections 200.80(b)(4), 200.83 and 230.406.

 
 

Exhibit 10.30    
    

LICENSE and SUPPLY AGREEMENT  

 By and Between  

 Immunicon Corporation  

 And  

 Research and Diagnostic Systems, Inc.  

        THIS LICENSE and SUPPLY AGREEMENT (hereinafter "Agreement"), dated and effective as of the Effective Date (as hereinafter defined) on behalf of each of the
parties hereto and their Affiliates (as hereinafter defined), is by and between Immunicon Corporation, a corporation organized and existing under the laws of the state of Delaware, having an office at
3401 Masons Mill, Suite 100, Huntingdon Valley, Pennsylvania 19006, together with its Affiliates (hereinafter collectively, "Immunicon"), and Research and Diagnostic Systems, Inc., a
corporation organized and existing under the laws of the state of Minnesota, having an office at 614 McKinley Place N.E., Minneapolis, Minnesota 55413, together with its Affiliates (hereinafter
collectively, "RDS"). 

WITNESSETH: 

        WHEREAS,
Immunicon possesses proprietary technology and skills in developing, manufacturing and labeling particles having magnetic properties, such as ferrofluids, which may be suitable
for various uses, such as in vitro diagnostic applications, and RDS possesses proprietary technology and skills in developing, manufacturing and
marketing antibodies, in particular monoclonal antibodies, which may have use in such applications; and 

        WHEREAS,
each party has evaluated the proprietary technology of the other party and each has determined that it now wishes to further enter into a business relationship concerning the
development, manufacturing, marketing and sales of products incorporating their respective proprietary technologies under the terms and conditions set forth herein; and 

        WHEREAS,
RDS wishes to receive from Immunicon, and Immunicon wishes to supply to RDS, under the terms and conditions set forth herein, portions of Immunicon's proprietary technology in
the form of ferrofluid conjugates produced by Immunicon initially; provided that the parties may agree in the future to negotiate in good faith the terms and conditions under which at least some of
such ferrofluid conjugates may be produced by RDS, and which incorporate certain of RDS's antibodies, for incorporation and repackaging by RDS into Licensed RDS Products (as hereinafter defined), and
associated Immunicon products, which are intended to be sold by RDS hereunder solely for life science research applications that do not require formal governmental regulatory approval prior to sale,
and in connection with such supply Immunicon is willing to grant to RDS a non-exclusive, world-wide, royalty-bearing license, under the terms and conditions of this Agreement,
to use, have used, sell and have sold Licensed RDS Products which include such conjugates, and such associated products, solely for the above-mentioned life science research applications; and 

        WHEREAS,
upon Immunicon's request, RDS is willing to negotiate in good faith with Immunicon the terms and conditions under which RDS would provide certain assistance to Immunicon in the
use of certain proprietary RDS technology for the [**] (as identified in Appendix C hereto) which may be useful in the development and commercialization of Immunicon
products. 

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        NOW,
THEREFORE, in consideration of the foregoing premises, the mutual covenants herein contained and other good and valuable consideration, the receipt and sufficiency of which are
hereby acknowledged, the parties hereto agree as follows: 

        1.    DEFINITIONS.    

        Certain
terms are used in this Agreement as specifically defined herein. In addition, the following terms shall have the meanings set forth in this Article 1: 

        1.1   "Affiliate"
when used with respect to either party, means any corporation, association, partnership, joint venture, trust, organization, or other business entity or
subdivision thereof that directly or indirectly controls, is controlled by or is under direct or indirect common control with such Party. 

        1.2   "Effective
Date" means August 14, 2003. 

        1.3   "IMMC
Conjugates" means magnetic reagents incorporating IMMC Technology, including without limitation [**] listed in Appendix A (which may
be updated from time to time be written agreement of the parties), that are produced by Immunicon using [**] supplied by RDS, and supplied to RDS by Immunicon in
[**] together with any necessary IMMC Technology for repackaging by RDS solely into Licensed RDS Products according to the terms and conditions of this Agreement. 

        1.4   "IMMC
Hardware" means Immunicon products, other than IMMC Conjugates, that are supplied by Immunicon to RDS hereunder for use in association with Licensed RDS Products;
IMMC Hardware which may be supplied under this Agreement is listed in Appendix A. 

        1.5   "IMMC
Technology" means patents and patent applications throughout the Territory owned by or licensed to Immunicon (hereinafter "IMMC Patent Rights") and other
proprietary information and unpatented or unpatentable know-how, which is directly related to IMMC Conjugates and relevant to the packaging, promotion, marketing and sale by RDS of
Licensed RDS Products. IMMC Patent Rights relevant to this Agreement as of the Effective Date are listed in Appendix D. Appendix D shall be updated by Immunicon from time to time as
necessary to reflect the filing and issuance of new patent applications and patents included in IMMC Patent Rights which are relevant to this Agreement,, including any and all United States patents
and patent applications and all other corresponding patents and patent applications throughout the Territory. 

        1.6   "IMMC
Trademark" means any trademarks authorized by Immunicon to be used by RDS in connection with Licensed RDS Products during the term of this Agreement; if any IMMC
Trademarks are authorized for use under this Agreement, they shall be listed in an Appendix E hereto. 

        1.7   "Licensed
RDS Products" means the authorized products that incorporate or utilize IMMC Conjugates and any associated IMMC Hardware, and which are packaged, marketed and
sold by RDS
hereunder solely for the Licensed Use. Licensed RDS Products shall be listed in Appendix C, the details of which shall be updated from time to time during the term of this Agreement. 

        1.8   "Licensed
Use" means use of Licensed RDS Products in any life science research use only application only by a end-user, provided that such life science
application is not a Regulated Use (as herein defined). For purposes of this Agreement, "Regulated Use" means any use that occurs in a clinical or
diagnostic laboratory environment which is approved by, or for which approval could or must be sought, from the United States Food and Drug Administration or from any comparable agency in any country
other than the United States, and the use or the results 

	**
	Certain information in these exhibits has been omitted and will be filed separately with the Securities and Exchange Commission pursuant to a confidential
treatment request under 17 C.F.R. Sections 200.80(b)(4), 200.83 and 230.406.

2

 

thereof
are subject to regulation or control by any governmental body or regulating authority. Licensed Use expressly excludes, by way of example but
not limitation: any human and veterinary in vivo or in vitro diagnostic application, such as screening,
diagnosis, staging or monitoring of cancer or any other disease; any in vivo imaging; or any therapeutic use. 

        1.9   "Territory"
means all countries of the world. 

        2.    TERM AND TERMINATION.    

        2.1   This
Agreement and the licenses, rights and obligations hereunder shall commence on the Effective Date, and continue for the life of the relevant IMMC Patent Rights,
unless terminated by either RDS or Immunicon upon six (6) months prior notice by the terminating party to the other party, or unless one of the termination options identified in this
Article 2 applies. 

        2.2    Termination by Mutual Consent.    This Agreement shall terminate upon the mutual written agreement of the
parties. 

        2.3    Termination for Financial Difficulties.    Either party shall have the right to terminate this Agreement upon
thirty (30) days prior notice to the other party, if such other party becomes involved in financial difficulties as evidenced: 

        a)    by
such other party's commencement of a voluntary case under any applicable bankruptcy code or statute, or by its authorizing, by appropriate proceedings, the
commencement of such a voluntary case; or 

        b)    by
such other party's failing to receive dismissal of any involuntary case under any applicable bankruptcy code or statute within sixty (60) days after initiation
of such action or petition; or 

        c)     by
such other party's seeking relief as a debtor under any applicable law of any jurisdiction relating to the liquidation or reorganization of debtors or to the
modification or alteration of the rights of creditors, or by consenting to or acquiescing in such relief; or 

        d)    by
the entry of an order by a court of competent jurisdiction finding such other party to be bankrupt or insolvent, or ordering or approving its liquidation,
reorganization, or any modification or alteration of the rights of its creditors or assuming custody of, or appointing a receiver or other custodian for, all or a substantial part of its property or
assets; or 

        e)    by
such other party making an assignment for the benefit of, or entering into a composition with, its creditors, or appointing or consenting to the appointment of a
receiver or other custodian for all or a substantial part of its property. 

        2.4    Termination for Material Breach.    If either party breaches or defaults in the performance or observance of
any of the material provisions of this Agreement, and such breach or default is not cured within sixty (60) days after the giving of notice by the other party specifying such breach or default,
the non-defaulting party shall have the right to terminate this Agreement, effective with ten (10) days further notice to the defaulting party. The failure by a party to exercise
its right to terminate this Agreement pursuant to this Section 2.4 in the event of any occurrence giving rise thereto shall not constitute waiver of its rights in the event of any subsequent
occurrence. 

        2.5   Following
the expiration of the relevant IMMC Patent Rights, Immunicon grants RDS a right of first negotiation to continue the use of IMMC Technology for the
development, production, use and sale of Licensed RDS Products, under such terms and conditions as may be negotiated by the parties in good faith. 

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        2.6   Except
as otherwise provided in this Agreement, upon any expiration or termination of this Agreement: 

        a)    All
rights, privileges and licenses granted hereunder shall immediately terminate and revert to the party granting same hereunder; b) each party shall promptly
return or provide to the other, upon request, all confidential information received from the other party and existing in tangible form and relevant to the rights and obligations under this Agreement,
except that each party may keep an archival copy of such confidential information in its legal department to verify its obligations under this Agreement; 

        c)     RDS
shall promptly destroy or transfer to Immunicon, at Immunicon's election, all marketing, labeling, or advertising materials relating to Licensed RDS Products or IMMC
Trademarks; and 

        d)    RDS
shall pay to Immunicon, within thirty (30) days following such expiration or termination, all amounts due to Immunicon pursuant to the terms and conditions of
this Agreement. 

        2.7   The
provisions of Articles 1, 10, 11, 14, 15 and Section 2.6 shall survive any expiration or termination of this Agreement, together with any other express right,
obligation or duty of the parties which by its nature would survive such expiration or termination. 

        3.    LICENSE GRANTS/USE OF RDS TECHNOLOGY BY IMMUNICON.    

        3.1   Immunicon
hereby grants to RDS, while this Agreement is in effect, the non-exclusive, royalty-bearing, limited right and license, without the right to
sublicense, under IMMC Technology: 

        a)    to
incorporate IMMC Conjugates supplied by Immunicon hereunder into Licensed RDS Products and to use IMMC Conjugates and IMMC hardware to develop and produce Licensed RDS
Products for the Licensed Use in the Territory; 

        b)    to
develop, produce, use, have used, sell and have sold Licensed RDS Products incorporating IMMC Conjugates and to use, have used, sell and have sold IMMC Hardware in
association with Licensed RDS Products, solely for the Licensed Use in the Territory, either directly to end-users or through RDS's standard distribution channels, where the Licensed RDS
Products or IMMC Hardware are sold as packaged by RDS (with RDS' standard packaging) and are not repackaged, derivatized, or incorporated into another product by a third party before transfer to the
ultimate consumer; and 

        c)     to
use or have used the IMMC Trademarks and IMMC Technology in the Territory solely in connection with the marketing, selling and distributing of Licensed RDS Products
and/or IMMC Hardware, solely for the Licensed Use in the Territory. 

        3.2   No
other rights or licenses are granted to RDS hereunder, it being expressly understood and agreed, by way of example but not limitation, that no right or license is
granted to RDS hereunder to research, develop, reproduce, copy or reverse engineer IMMC Conjugates, IMMC Hardware or any other aspect of IMMC Technology, to make or have made any IMMC Conjugates or
IMMC Hardware, to otherwise use or sell IMMC Conjugates, Licensed RDS Products or IMMC Hardware except as permitted herein, or to directly or indirectly develop, produce, market, promote, encourage
use of, exploit, offer for sale, sell or have sold, distribute or have distributed, or otherwise dispose of, IMMC Conjugates, Licensed RDS Products or IMMC Hardware in the Territory for any use other
than the Licensed Use. 

        3.3   Immunicon
shall not, for a period of [**] following the Effective Date, without the prior written consent of RDS, enter into a supply arrangement
to sell IMMC Conjugates to any third party for use or incorporation in a product to be sold for the Licensed Use, except to 

	**
	Certain information in these exhibits has been omitted and will be filed separately with the Securities and Exchange Commission pursuant to a confidential
treatment request under 17 C.F.R. Sections 200.80(b)(4), 200.83 and 230.406.

4

 

third
parties to whom Immunicon has a contractual obligation, which was entered into prior to the Effective Date of this Agreement, to sell such IMMC Conjugates. After such
[**] period, if requested by RDS, Immunicon agrees that it will negotiate in good faith with RDS to extend such period upon such terms and conditions as may be agreed by the
parties in writing. Notwithstanding the foregoing, while this Agreement is in effect, Immunicon shall, by way of example and not by way of limitation, have and retain the rights to develop, make, have
made, market, sell, distribute and use and have used any IMMC Conjugate, IMMC Hardware or any other product or material incorporating or utilizing IMMC Technology whether or not substantially
equivalent or similar to any IMMC Conjugate supplied to RDS hereunder or any Licensed RDS Product, outside the scope of the Licensed Use, and to conduct any research and development or testing
activity with respect thereto. 

        3.4   If,
during the term of this Agreement, Immunicon desires to grant rights to RDS with respect to new Licensed RDS Products to be marketed and sold by RDS within the scope
of the Licensed Use as herein defined but which are not set forth in Appendix C as of the Effective Date, the parties shall consider entering into a separate written definitive agreement, or an
appropriate amendment to this Agreement, with respect thereto, as determined by RDS and Immunicon through good faith negotiations. 

        3.5   Immunicon
may request the assistance of RDS in the utilization of proprietary RDS technology for the [**] (as identified in Appendix C) of
up to [**] and [**], for use in the development of Immunicon products. RDS agrees that if the [**] are part of a
[**] to RDS, RDS shall provide such assistance as part of RDS' ongoing new product development activities without cost or charge to Immunicon. However, In the event that RDS
deems it necessary that additional laboratory work will be required to provide the assistance that Immunicon has requested, both parties agree to negotiate in good faith to enter into a separate
research agreement containing the detailed terms and conditions under which such assistance is provided and the additional costs to RDS of such additional laboratory work will be reimbursed in whole
or in part by Immunicon. In the event Immunicon desires to commercialize any products that may result from the foregoing activities, such commercialization shall be under the terms and conditions of a
separate definitive written agreement negotiated by the parties in good faith. 

        4.    MARKETING OF LICENSED RDS PRODUCTS.    

        4.1   RDS
shall in good faith make reasonable commercial efforts and expenditures to diligently market and promote sales of Licensed RDS Products for the Licensed Use in the
Territory. RDS's good faith efforts and expenditures shall be at least comparable to RDS's efforts and expenditures for other RDS products. Immunicon shall from time to time furnish RDS with IMMC
Technology as and to the extent Immunicon reasonably determines is necessary to assist RDS in efforts to commercialize Licensed RDS Products. Management reviews shall be held at intervals mutually
agreed between the parties, to review goals, status of marketing and sales activities with respect to Licensed RDS Products and associated IMMC Hardware, customers and new developments for the
Licensed RDS Products. 

        4.2   RDS
shall provide Immunicon with information about any proposed Licensed RDS Products and any associated IMMC Hardware to be marketed and promoted for sale by RDS,
whether or not as a catalog item, prior to the first commercialization of such proposed Licensed RDS Products and any associated IMMC Hardware, for review and approval by Immunicon for compliance with
the terms and conditions of this Agreement. In order to accomplish the foregoing, RDS will inform Immunicon of Licensed RDS Products that are being developed as far as practicable in advance of
commercialization thereof, and will provide literature and labels relating 

	**
	Certain information in these exhibits has been omitted and will be filed separately with the Securities and Exchange Commission pursuant to a confidential
treatment request under 17 C.F.R. Sections 200.80(b)(4), 200.83 and 230.406.

5

 

to
such Licensed RDS Products within a reasonable time after they are available. Examples of such further information that will be provided to Immunicon by RDS, when available, are copies of any
written information, such as advertising materials or information or data sheets, which refer to or describe Licensed RDS Products. Immunicon shall not unreasonably withhold such approval. 

        4.3    Product Marking.    RDS shall place or cause to have placed on all Licensed RDS Products and IMMC Hardware
marketed or sold hereunder, or on the accompanying product literature, a suitable and clearly legible legend that restricts such Licensed RDS Products and IMMC Hardware to the Licensed Use, such
legend to be in the language(s) of the labeling of such Licensed RDS Products and IMMC Hardware where the same are marketed and/or sold and in conformance with all applicable governmental regulatory
requirements. Such legend shall include, by way of example but not limitation, the phrase "This product is licensed solely for use in life science applications that are not clinical diagnostic or
therapeutic applications" or substantially equivalent language translated into the language of the area where it is marketed and sold, indicating appropriate restrictions on use of Licensed RDS
Products and IMMC Hardware in accordance with the rights granted RDS hereunder, and in accordance with US Food and Drug Administration and any other governmental authority labeling requirements in any
country for products that are not approved for a use that is a Regulated Use. In addition, the packaging for all Licensed RDS Products and any accompanying literature, and any catalog listings,
informational or promotional literature used in connection with the sales and/or marketing thereof, shall bear a clearly visible legend thereon with substantially the following wording, translated
into the language of the area where it is marketed and sold: "This product utilizes and/or contains technology licensed from Immunicon Corporation, Huntingdon Valley, Pennsylvania 19006 USA, which is
covered by one or more claims of United States and International patents and/or pending patent applications." 

        4.4   RDS
shall provide a copy of the initial versions of labels, product literature and/or catalog listings for Licensed RDS Products and any associated IMMC Hardware, to
Immunicon for review and approval in accordance with the requirements of Sections 4.3, prior to the first distribution, sale or release of the associated Licensed RDS Product and/or IMMC Hardware to
the market, but shall not be required to provide subsequent variations of the foregoing which involve changes in non-substantive variable information such as changes in catalog number,
quantity, lot number, etc. 

        4.5   RDS
hereby recognizes and acknowledges that because of the legal and regulatory requirements concerning certain uses of IMMC Technology, including IMMC Hardware, and
Licensed RDS Products, Immunicon has a legitimate interest in assuring that the foregoing are not used in inappropriate and impermissible ways. Accordingly, in addition to the product marking
requirements of Section 4.3 above, RDS shall use reasonable commercial efforts to monitor its customers and end users of Licensed RDS Products and associated IMMC Hardware sold hereunder to
assure compliance with the Licensed Use hereunder, and shall promptly inform Immunicon in writing of any use by any such customer or end user of which it becomes aware that is not in accordance with
the Licensed Use. 

        4.6   RDS
shall make available to Immunicon upon request scientific research publications relating to technical advances in and useful modifications of Licensed RDS Products
that shall come to the knowledge of RDS. 

        5.    PURCHASE OF IMMC CONJUGATES AND IMMC HARDWARE.    

        5.1   Subject
to all the terms and conditions of this Agreement, Immunicon shall sell IMMC Conjugates to RDS for incorporation into Licensed RDS Products which have been
developed and produced by RDS for use and sale by RDS solely for the Licensed Use, and also sell to RDS any IMMC Hardware that RDS may reasonably require in association with such use and sale of such 

6

 

Licensed
RDS Products, in such commercially reasonable quantities as Immunicon is capable of supplying. RDS shall purchase its entire requirements of such IMMC Conjugates and IMMC Hardware exclusively
from Immunicon. While this Agreement is in effect and except as provided in Article 11, RDS shall not, without Immunicon's prior written consent, after having introduced commercially to the
market a particular Licensed RDS Product, sell any other magnetic particle separation product or substance substantially capable of being used in a similar manner to that of such Licensed RDS Product
or used in a similar manner to IMMC Conjugates incorporated into such Licensed RDS Product. For the purposes of this Section 5.1, "in a similar manner" means the use or incorporation into a
product as a substitute for functionality for which such Licensed RDS Product or IMMC Conjugate is technically and commercially suitable, but not use or incorporation into a product for which such
Licensed RDS Product or IMMC Conjugate is not technically or commercially suitable; provided, however, that nothing in this sentence shall be construed to grant RDS the right to infringe any patent or
other proprietary right of Immunicon. 

        5.2   The
IMMC Conjugates to be produced and supplied to RDS hereunder shall be produced from and include only antibodies and any associated material and substances supplied
by RDS to Immunicon. Immunicon shall not be obligated to utilize any other antibodies or other associated material and substances, and Immunicon shall have no obligation to produce any quantities of
IMMC Conjugates for supply to RDS hereunder if such production and/or supply is determined in good faith by Immunicon's management to be technically or commercially not feasible for any reason,
including without limitation the failure of RDS to supply sufficient quantities or quality of antibodies to Immunicon for use in IMMC Conjugates. The IMMC Conjugates and IMMC Hardware to be supplied
and sold by Immunicon and purchased by RDS hereunder shall conform to the specifications for same as set forth in Appendix A, which may be amended from time to time by mutual agreement of the
parties in writing. 

        5.3   Upon
receipt by Immunicon of a purchase order or equivalent document for IMMC Conjugates and/or IMMC Hardware from RDS, Immunicon shall use reasonable commercial efforts
to meet the schedule for delivery requested by RDS in such document. For each item listed in Appendix A, the parties shall establish by mutual agreement a commercially reasonable and economical
delivery schedule, and Immunicon shall have no obligation to manufacture or supply IMMC Conjugates or IMMC Hardware to RDS in advance of such delivery schedule. Immunicon shall notify RDS just prior
to the shipment of an order. 

        5.4   Except
as otherwise mutually agreed in writing, Immunicon shall ship IMMC Conjugates and IMMC Hardware FOB to RDS by a mutually acceptable common carrier from the
facility in which such items are manufactured or obtained by Immunicon, and title to and risk of loss of such items shall pass to RDS upon their delivery to such common carrier. 

        6.    MAINTENANCE OF QUALITY/TRADEMARKS.    

        6.1    Quality Standards.    Immunicon shall be responsible for maintaining commercially acceptable quality control
standards in accordance with accepted industry practices in all manufacturing relating to the IMMC Conjugates and IMMC Hardware that it supplies to RDS hereunder, and RDS shall be responsible for
maintaining commercially acceptable quality control standards in accordance with accepted industry practices for all Licensed RDS Products incorporating or utilizing IMMC Conjugates and IMMC Hardware. 

        6.2    Use of IMMC Trademarks.    The IMMC Trademarks shall be solely owned by Immunicon. RDS agrees to use the IMMC
Trademarks solely in connection with the Licensed RDS Products as indicated in Appendix A and in accordance with trademark standards that may be set by Immunicon and provided to RDS, and to
avoid taking any action that would in any manner impair or detract from the value of the IMMC Trademarks or the goodwill and reputation of Immunicon. RDS hereby acknowledges Immunicon's sole ownership
of the IMMC Trademarks and related 

7

 

goodwill.
RDS agrees to provide a copy of the intended use of any such IMMC Trademarks to Immunicon for review and approval prior to such use, pursuant to Section 4.4 above. 

        7.    CONSIDERATION/PRICING    

        7.1   In
consideration of the supply of IMMC Conjugates and IMMC Hardware hereunder, RDS shall compensate Immunicon for the indicated quantities of IMMC Conjugates and IMMC
Hardware as set forth in the pricing schedule set forth in Appendix B and in addition shall pay to Immunicon the royalty set forth in this Section 7.1 as follows: 

        a)    RDS
shall pay to Immunicon [**] of RDS' Net Sales of Licensed RDS Products which comprise IMMC Conjugates or IMMC Hardware which are not at the
time of sale assembled into a kit or other form of packaging wherein such IMMC Conjugates or IMMC Hardware are bundled, sold together or combined with other Licensed RDS Products or other products
sold by RDS; and 

        b)    RDS
shall pay to Immunicon [**] of RDS' Net Sales of Licensed RDS Products which comprise at the time of sale IMMC Conjugates and/or IMMC Hardware
assembled into a kit or other form of packaging wherein such IMMC Conjugates and/or IMMC Hardware are bundled, sold together or combined with other Licensed RDS Products or other products sold by RDS. 

        7.2   "Net
Sales" for purposes of royalty calculation under this Agreement means the actual sales of Licensed RDS Products by RDS and its Affiliates in the ordinary course of
business to third party purchasers who are not Affiliates of either party. For the avoidance of doubt and by way of example and not limitation, Net Sales shall not include any transfer of any product
which is used as a control, calibrator or as a stand-alone reagent, or which is used by RDS or its Affiliates in research, product development, demonstration or similar activities, or which is
provided by RDS to an Affiliate, or is used by an Affiliate, or which is provided to any third party as free product, marketing or sales samples or the like or as a product sample for evaluation, or
which is provided for use in research or clinical trials or similar studies and activities. 

        7.3   Payments
of royalty on account of Net Sales by RDS and its Affiliates due Immunicon hereunder shall be accounted for by RDS and paid to Immunicon within thirty
(30) days following the close of the RDS accounting period for each calendar quarter during the term of this Agreement. 

        7.4   Any
royalty or other payment that may be due to be paid to any third party on account of use, sales or other transfer of RDS Technology as provided under the terms and
conditions of this Agreement shall be accounted for and paid solely by RDS, and RDS hereby holds Immunicon harmless from and against any and all liabilities on account thereof. 

	**
	Certain information in these exhibits has been omitted and will be filed separately with the Securities and Exchange Commission pursuant to a confidential
treatment request under 17 C.F.R. Sections 200.80(b)(4), 200.83 and 230.406.

8

   
        8.    FORECASTS; ORDERS AND DELIVERIES.    

        8.1   RDS
shall deliver to Immunicon, within thirty (30) days after the Effective Date, RDS's forecast for its requirements of IMMC Conjugates and IMMC Hardware for
Licensed RDS Products for the remainder of 2003. Thereafter, at least sixty (60) days prior to the start of the next and each succeeding calendar quarter, RDS shall provide Immunicon with its
non-binding best estimate of its requirements for IMMC Conjugates and IMMC Hardware for the next succeeding three (3) calendar quarters. Immunicon shall not ship the forecasted
items to RDS, however, until RDS places an order. 

        8.2   It
is the intent of the parties that RDS and Immunicon shall cooperate with each other with respect to changes in their requirements and capacity so that each party may
use reasonable commercial efforts to efficiently accommodate the needs of the other. Accordingly, in addition to the forecasts of quarterly requirements required by Section 8.1, RDS shall
discuss with Immunicon any dramatic changes in its requirements, and Immunicon shall use reasonable commercial efforts, consistent with its then current capacity, to accommodate such dramatic changes
within the next two (2) calendar quarters. In no event shall this Agreement be deemed to be breached or subject to termination if RDS's requirements hereunder should be reduced to zero from
time to time, or if Immunicon shall fail to supply all of RDS' requirements of IMMC Conjugates or IMMC Hardware from time to time. 

        9.    ACCESS TO BOOKS AND RECORDS.    

        From
time to time during the term of this Agreement, but not more frequently than two(2) times per year, RDS shall upon reasonable notice from Immunicon afford reasonable access to its
offices to independent public accountants of Immunicon or other appropriate agents of Immunicon and permit such accountants or agents to inspect RDS' information, books and records, subject to
appropriate assurances of confidentiality, to verify RDS' accounting of Net Sales, and the accuracy and completeness of the financial and other information related to the fulfillment by Immunicon of
its obligations hereunder. In the event such inspection shall reveal an underpayment of royalty by RDS of [**] or more, RDS shall reimburse to Immunicon all of Immunicon's
costs and expenses of such inspection and immediately pay to Immunicon such underpayment. 

        10.    REPRESENTATIONS, WARRANTIES AND COVENANTS.    

        10.1      Immunicon's Representations, Warranties, and Covenants.    Immunicon hereby represents,
warrants, and covenants the following: 

        a)    Immunicon
is a corporation duly organized, existing and in good standing under the laws of the state of Delaware and the United States of America, with full right, power
and authority to enter into and perform this Agreement and to grant the license to RDS hereunder and all of the rights, powers, and authorities herein granted. 

        b)    The
execution, delivery and performance of this Agreement do not conflict with, violate, or breach any agreement to which Immunicon is a party. 

        c)     This
Agreement has been duly executed and delivered by Immunicon and is a legal, valid and binding obligation enforceable against Immunicon in accordance with its terms. 

        d)    Immunicon
shall comply with all applicable laws, consent decrees, and regulations of any federal, state, or other governmental authority. 

	**
	Certain information in these exhibits has been omitted and will be filed separately with the Securities and Exchange Commission pursuant to a confidential
treatment request under 17 C.F.R. Sections 200.80(b)(4), 200.83 and 230.406.

9

 

        10.2      RDS's Representations, Warranties, and Covenants.    RDS hereby represents, warrants, and
covenants the following: 

        a)    RDS
is a corporation duly organized, existing and in good standing under the laws of the state of Minnesota and the United States of America, and has the full right,
power, and authority to enter into and perform this Agreement and to grant the license to Immunicon hereunder and all of the rights, powers, and authorities herein granted. 

        b)    The
execution, delivery, and performance of this Agreement do not conflict with, violate, or breach any agreement to which RDS is a party. 

        c)     This
Agreement has been duly executed and delivered by RDS and is a legal, valid, and binding obligation enforceable against RDS in accordance with its terms. 

        d)    RDS
shall comply with all applicable laws, consent decrees, and regulations of any federal, state, or other governmental authority. 

        10.3   Both
parties hereto acknowledge that they have had the full opportunity to have this Agreement reviewed and approved by their own legal counsel and other
advisors, are entering into this Agreement having made their own independent assessment and judgment concerning the business opportunity and legal rights and obligations under this Agreement and the
terms and conditions hereof, and have not been induced to enter into this Agreement in any way or by any promise not expressly set forth herein. This Agreement has been jointly drafted by the parties
and neither this Agreement nor any provision hereof shall be construed against either party merely because such party primarily or fully drafted any provision hereof. 

        10.4   Immunicon
shall indemnify, defend, and hold harmless RDS from any and all liability, damages, loss, cost, expense, suits, claims and judgments (including
reasonable attorney's fees and costs) arising or alleged to arise directly from Immunicon's breach of its warranties herein or the conduct of Immunicon or its officers or employees or arising from the
production use or sale of Licensed IMMC Products by Immunicon, or the supply of IMMC Conjugates or IMMC Hardware to RDS hereunder, except for any such liability, damages, loss, cost, expense, suits,
claims and judgments caused by RDS's breach of its warranties herein. 

        10.5   RDS
shall indemnify, defend, and hold harmless Immunicon from any and all liability, damages, loss, cost, expense, suits, claims and judgments (including
reasonable attorney's fees and costs) arising or alleged to arise directly from the RDS' breach of its warranties herein or the conduct of RDS or its officers or employees or arising from the use or
sale of Licensed RDS Products by RDS, except for any such liability, damages, loss, cost, expense, suits, claims and judgments caused by Immunicon's breach of its warranties herein. 

        10.6      Indemnification Procedure.    In the event of any claim under this Article 10, the party
claiming the right to indemnity (the "Claimant") shall promptly notify the indemnifying party (the "Indemnitor") of such claim. Thereafter: 

        a)    The
Indemnitor will undertake the defense thereof by representatives of Indemnitor's own choosing reasonably satisfactory to Claimant. Claimant may, at its sole option
and expense, elect to participate in such defense, but the Indemnitor shall assume the direction and control of such defense. The Claimant
shall, at its expense, assist in and cooperate with the Indemnitor and its agents and insurers in the defense of such claims. 

        b)    If
Indemnitor, within a reasonable time after notice of any such claim, fails to defend, Claimant will (upon further notice to the Indemnitor) have the right to undertake
the defense, compromise or settlement of such claim for the account of Indemnitor, subject to the right of Indemnitor to assume the defense of such claim with counsel reasonably satisfactory to
Claimant at any time prior to settlement, compromise or final determination thereof. 

10

 

        c)     Anything
in this Article 10 to the contrary notwithstanding, Indemnitor shall not, without Claimant's prior written consent, settle or compromise any claim or
consent to entry of any judgment with respect to any claim for anything other than money damages paid by Indemnitor which would have any adverse effect on Claimant. Indemnitor may, without Claimant's
prior written consent, settle or compromise any claim or consent to entry of any judgment with respect to any claim which requires solely money damages paid by Indemnitor and which includes as an
unconditional term thereof the release of Claimant by the plaintiff from all liability in respect of such claim. 

        10.7      Rejection and Return.    If any of the IMMC Conjugates or IMMC Hardware supplied by Immunicon to
RDS hereunder breaches any warranty of Immunicon herein due to the fault of Immunicon and not due to any fault of RDS Technology or any substance or material supplied by RDS which is used or
incorporated therein, RDS shall promptly notify Immunicon of such breach and may reject such IMMC Conjugates or IMMC Hardware within ninety (90) days after such breach should have reasonably
been discovered and return such IMMC Conjugates or IMMC Hardware, if applicable, to Immunicon at Immunicon's expense. 

        11.    FORCE MAJEURE.    

        11.1   Neither
party hereto shall be considered in default in the performance of its obligations hereunder to the extent that the performance thereof is
prevented or delayed by strikes, labor difficulties, war (declared or undeclared), act of God or the public enemy, acts of terrorism, rebellions, civil strife, riots, interference by civil or military
authorities, compliance with governmental laws, or rules and regulations or any other cause which is beyond the control of such party; provided, however, that the party whose performance is prevented
from due performance hereunder by the force majeure shall use its reasonable efforts to remove the disability and recommence due performance hereunder at the earliest reasonable time. 

        11.2   On
the happening of an event of force majeure, the party forced by the event of force majeure to suspend performance (the "Suspending Party") shall
promptly notify the other party (the "Recipient Party") of the event of force majeure, the cause thereof and, to the extent reasonably possible its best estimate of the duration of the suspension (the
"Failure Period"). The notice described in this Section shall hereinafter be referred to as the "Suspension Notice." 

        11.3   If
a failure of performance due to a force majeure occurs and continues for a period in excess of fourteen (14) days, or if a Suspension Notice
advises the Recipient Party that a failure of performance will continue for a period in excess of fourteen (14) days, then the Recipient Party may, at its option, contract with any third person
for an alternate supply of any item or service to which the failure of performance applies. Any such contract shall be referred to hereafter as an "Alternate Source Contract." 

        11.4   The
Recipient Party shall use all good faith, consistent with sound business practice, to obtain an Alternate Source Contract which will not extend for a
period longer than the length of any stated Failure Period; provided, however, no Alternate Source Contract shall extend for a period longer than six (6) months unless consented to in writing
by the Suspending Party, or unless the Failure Period described in any Suspension Notice is greater than six (6) months (in which case an Alternate Source Contract may extend for the length of
the Failure Period described in the Suspension Notice). 

        11.5   If
any Failure Period continues for a period in excess of twelve (12) months, or if the Suspension Notice states that the Failure Period will
continue for greater than twelve (12) months, the Recipient Party may at its option terminate this Agreement, only with respect to the Licensed RDS Products or Licensed IMMC Products, as the
case may be, which are subject to such force 

11

 

majeure,
by thirty (30) days written notice. If not so terminated, however, this Agreement shall remain in full force and effect until this Agreement is terminated by its terms. 

        12.    ASSIGNMENT.    

        Except
as otherwise expressly provided herein, this Agreement may not be assigned by either party hereto, whether by operation of law or otherwise, without the prior written consent of
the other party hereto, and any such attempted assignment shall be void and unenforceable; provided, however, that either party may assign its rights and obligations hereunder without the consent of
the other party to an Affiliate of such party, or to a successor in interest to substantially all of the business or such party or of the stock, equity or assets of such party to which this Agreement
relates. 

        13.    NOTICES.    

        All
notices which are required or permitted to be given pursuant to the terms of this Agreement shall be in writing and shall be deemed effective: (i) upon receipt if given in
writing and delivered personally; or (ii) five (5) business days after it shall have been deposited in the regular mail, registered or certified mail, postage prepaid; or
(iii) one (1) day after it shall have been delivered to an overnight courier service, such as Federal Express, all charges prepaid, addressed 

        as
follows: 

If
to RDS, to: 

Research
and Diagnostic Systems, Inc.

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

Attention: President 

And

If
to Immunicon, to: 

Immunicon
Corporation

3401 Masons Mill, Suite 100

Huntingdon Valley, PA 19006 

Attention:
Edward L. Erickson

Chairman, President and Chief Executive Officer

Phone: 215.830.0777

Fax: 215.830.0751 

        Any
of the addresses or addressees set forth in this Article may be changed from time to time by written notice from the party requesting the change. 

        14.    CONFIDENTIALITY OF INFORMATION.    

        14.1   The
parties may wish, from time to time in connection with this Agreement, to disclose certain of their confidential information to each other. While this
Agreement is in effect and for five (5) years thereafter, all information disclosed hereunder to a party by the other party shall be considered confidential information and a party receiving
any such confidential information (the "Receiving Party") shall not itself use for any purpose other than for which it was disclosed, and shall prevent the disclosure to third parties of, any and all
of such confidential information, provided that the Receiving Party's obligation hereunder shall not apply to information that: 

        a)    is
already in the Receiving Party's possession at the time of disclosure thereof, as evidenced by its written records, and was not previously received under an obligation
of confidentiality to the party disclosing the confidential information; 

12

 

        b)    is
or subsequently becomes part of the public domain through no fault or action of the Receiving Party; 

        c)     is
subsequently received by the Receiving Party from a third party having no obligation of confidentiality to the party disclosing the confidential information; or 

        d)    is
disclosed to third parties as required by law or governmental regulation. 

        14.2   Section 14.1
notwithstanding, information disclosed by one party to another shall still be deemed confidential information of the party disclosing
such information subject to the protection of this Article 14 if such disclosed information is 

        a)    a
specific embodiment that is only generally described by information in the public domain or the Receiving Party's possession or 

        b)    a
combination that can be pieced together and reconstructed from multiple sources, none of which shows the whole combination of materials, its principle of operation, and
method of use. 

        15.    CONTRACT INTERPRETATION.    

        15.1    Governing Law.    This Agreement shall be governed by and construed in accordance with the laws of the State
of Delaware and the United States of America, without giving regard to choice of law or conflict of law provisions. 

        15.2    Publicity.    Neither party shall issue any press release or other publicity materials, or make any
presentation with respect to the existence of this Agreement or the terms and conditions hereof without the prior written consent of the other party, which consent shall not be unreasonably withheld.
This restriction shall not apply to disclosures required by law or regulation, including without limitation as may be required in connection with any filings made with the United States Securities and
Exchange Commission or by the disclosure policies of a major Stock or Securities Exchange. 

        15.3    Modification and Amendment.    No supplement, modification or amendment of this Agreement, including the
Appendices thereof, shall be binding unless in writing and executed by RDS and Immunicon. 

        15.4    Severability.    To the extent that any provision of this Agreement is found by a court of competent
jurisdiction to violate any applicable law or regulation in any jurisdiction, or does so in the opinion of counsel mutually acceptable to both parties, such provision shall be deemed modified only in
that jurisdiction and then only to the extent necessary to comply with such law or regulation. In such circumstances, the parties agree to negotiate in good faith amendments to this Agreement designed
to restore to the parties the economic benefits they held under this Agreement prior to the modification. 

        15.5    Counterparts and Headings.    This Agreement may be executed in one or more counterparts, each of which shall
be deemed an original, but all of which together shall constitute one and the same instrument. All headings and captions are inserted for convenience of reference only and shall not affect the meaning
or interpretation of any provision hereof. 

        15.6    Relationship of the Parties.    The status of Immunicon and RDS hereunder is solely that of independent
contractors. This Agreement shall not create an agency, partnership, joint venture, or employer/employee relationship between the parties, and nothing hereunder shall be deemed to authorize either
party to act for, represent or bind the other except as expressly provided in this Agreement. 

13

 

        15.7    Waiver.    No waiver of any right under this Agreement shall be deemed effective unless contained in writing
and signed by the party entitled to grant such waiver, and no waiver of any right shall be deemed to be a waiver of any future right or any other right arising under this Agreement. All rights,
remedies, undertakings, obligations and agreements contained in this Agreement shall be cumulative and none of them shall be a limitation of any other remedy, right, undertaking, obligation or
agreement. 

        15.8    Patents and Trademarks.    No right or license is granted by either party hereunder, except as expressly
stated herein, to use or practice any patent rights of the other party, or to use the name, trademarks or tradenames of the other party. Nothing in this Agreement shall be construed as conferring any
right on either party to use or exploit any trade secret or other proprietary right of the other party, except as expressly set forth herein or as may be otherwise separately agreed in writing by the
parties. 

        15.9    Dispute Resolution.    In the event of any dispute between the parties concerning this Agreement, the parties
shall first attempt a resolution thereof by referring the dispute to senior management representatives of each party who shall discuss the matter between them and attempt to reach a reasonable
compromise or other disposition of the dispute. In the event such a compromise or disposition cannot be achieved, the dispute shall be referred to Endispute or another similar mutually acceptable
dispute resolution organization for a decision resolving the dispute, in accordance with the rules of dispute resolution proceedings of such organization, which decision shall be binding upon the
parties. The parties shall in any event share equally all costs and expenses involved in any such dispute resolution proceeding. 

        15.10    Entire Agreement.    This Agreement constitutes the entire agreement between the parties hereto relating to
the subject matter hereof and supersedes all prior or contemporaneous negotiations, representations, agreements and understandings of the parties relating thereto, whether written or oral; provided,
however, that the relevant provisions of any confidential disclosure agreement, material transfer agreement, stock purchase agreement or similar agreement previously or contemporaneously entered into
between the parties shall survive to the extent applicable to the rights, duties and obligations of the parties thereunder. Any Appendices referred to in this Agreement are incorporated by reference
and made a part of this Agreement. The terms of any purchase order, equivalent document or acknowledgment prepared in connection with this Agreement shall be binding on the parties only to the extent
not inconsistent herewith. 

        IN
WITNESS WHEREOF, the parties hereto have set their hands through their duly authorized representatives, whereby they evidence their intention to be legally bound. 

	Research and Diagnostic Systems, Inc.	 	Immunicon Corporation
	

By:	

/s/  THOMAS E. OLAND      
	
 	

By:	

/s/  EDWARD L ERICKSON      

	Name:	Thomas E. Oland
	 	Name:	Edward L Erickson

	Title:	President
	 	Title:	Chairman, President and CEO

	Date:	Aug. 12, 2003
	 	Date:	    

14

APPENDIX A: IMMC CONJUGATES and IMMC HARDWARE, Corresponding IMMC Trademark, Relevant Specifications, and Delivery Schedule  

	Item
 
	 	Corresponding IMMC Trademark
	 	Relevant Specifications
	 	Delivery Schedule

	IMMC Conjugates	 	[to be determined]	 	To be mutually agreed upon	 	To be mutually agreed upon
	

IMMC HARDWARE	
 	

[to be determined]	
 	

To be mutually agreed upon	
 	

To be mutually agreed upon

Appendix A
agreed to and accepted by: 

	Research and Diagnostic Systems, Inc.	 	Immunicon Corporation
	

By:	

/s/  THOMAS E. OLAND      
	
 	

By:	

/s/  EDWARD L ERICKSON      

	Name:	Thomas E. Oland
	 	Name:	Edward L Erickson

	Title:	President
	 	Title:	Chairman, President and CEO

	Date:	Aug. 12, 2003
	 	Date:	August 14, 2003

APPENDIX B: Transfer Pricing Schedule, Unit Size, Minimum Order*
  15.10.1.1.1.1.1.1.1 

	Item
 
	 	Unit Size
	 	Minimum Order
	 	Transfer Pricing Schedule

	[**]	 	 	 	[**]

 

(maybe mutually modified)	 	[**]

  

IMMC agrees to ship the [**]
	

[**]

  

[**]	
 	

 	
 	

(to be mutually agreed upon by the parties)	
 	

[**] The parties agree that they will negotiate in good faith commercially reasonable terms and conditions of a further written agreement or amendment to this Agreement to permit RDS, at a mutually agreed upon later date, to conjugate this or other
antibodies to [**] with the necessary instruction provided by Immunicon.
	

[**]	
 	

 	
 	

[**]

  

(maybe mutually modified)	
 	

[**]

	*
	Immunicon
will make available IMMC magnets as part of IMMC Hardware to RDS at [**] 

Appendix B
agreed to and accepted by: 

	Research and Diagnostic Systems, Inc.	 	Immunicon Corporation
	

By:	

/s/  THOMAS E. OLAND      
	
 	

By:	

/s/  EDWARD L ERICKSON      

	Name:	Thomas E. Oland
	 	Name:	Edward L Erickson

	Title:	President
	 	Title:	Chairman, President and CEO

	Date:	Aug. 12, 2003
	 	Date:	August 14, 2003

	**
	Certain information in these exhibits has been omitted and will be filed separately with the Securities and Exchange Commission pursuant to a confidential
treatment request under 17 C.F.R. Sections 200.80(b)(4), 200.83 and 230.406.

APPENDIX C:  

LICENSED RDS PRODUCTS:  

	Authorized Products
 
	 	Description
	 	Notes

	LICENSED PRODUCTS:	 	[**]

[**]

[**]

[**]

[**]

  

[**]

[**]

[**]

[**]

[**]

[**]

[**]	 	RDS may amend this list by written notice to Immunicon, with the understanding that such new items are subject to the agreed upon royalties hereunder and all other terms and conditions of this Agreement.

     

	Reagent Development
 
	 	Description
	 	Notes

	[**]

  

[**]	 	[**]	 	The parties agree that Immunicon may request R&D Systems to add to this reagent development list in accordance with Section 3.5 hereunder
	
	 	 	 	 

Appendix C
agreed to and accepted by: 

	Research and Diagnostic Systems, Inc.	 	Immunicon Corporation
	

By:	

/s/  THOMAS E. OLAND      
	
 	

By:	

/s/  EDWARD L ERICKSON      

	Name:	Thomas E. Oland
	 	Name:	Edward L Erickson

	Title:	President
	 	Title:	Chairman, President and CEO

	Date:	Aug. 12, 2003
	 	Date:	August 14, 2003

	**
	Certain information in these exhibits has been omitted and will be filed separately with the Securities and Exchange Commission pursuant to a confidential
treatment request under 17 C.F.R. Sections 200.80(b)(4), 200.83 and 230.406.

APPENDIX D: Patent Coverage included in IMMC Patent Rights  

	Item
 
	 	Relevant Patents

	IMMC Patent Rights:	 	[**]

  

[**]

  

[**]

  

[**]

  

[**]

  

[**]
	IMMC HARDWARE: Magnets	 	[**]

 

[**]
	IMMC Foreign Counterparts	 	[**]

  

[**]

  

[**]
	
	 	 

Appendix D
agreed to and accepted by: 

	Research and Diagnostic Systems, Inc.	 	Immunicon Corporation
	

By:	

/s/  THOMAS E. OLAND      
	
 	

By:	

/s/  EDWARD L ERICKSON      

	Name:	Thomas E. Oland
	 	Name:	Edward L Erickson

	Title:	President
	 	Title:	Chairman, President and CEO

	Date:	Aug. 12, 2003
	 	Date:	August 14, 2003

	**
	Certain information in these exhibits has been omitted and will be filed separately with the Securities and Exchange Commission pursuant to a confidential
treatment request under 17 C.F.R. Sections 200.80(b)(4), 200.83 and 230.406.

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Exhibit 10.30QuickLinks
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Exhibit 10.31    
    

MASTER SUPPLY AGREEMENT  

 BETWEEN  

 IMMUNICON CORPORATION  

 AND  

 ASTRO INSTRUMENTATION L.L.C.  

MASTER SUPPLY AGREEMENT  

 
	**
	Certain information in these exhibits has been omitted and will be filed separately with the Securities and Exchange Commission pursuant to a confidential
treatment request under 17 C.F.R. Sections 200.80(b)(4), 200.83 and 230.406.

        This
Master Supply Agreement is effective on the date of last signature ("Effective Date") by and between Immunicon Corporation, 3401 Masons Mill Road, Suite 100, Huntingdon Valley, PA
19006 and Astro Instrumentation L.L.C., 13500 Darice Parkway, Strongsville, Ohio 44149. 

        WHEREAS, Astro Instrumentation L.L.C., the supplier, shall be referred to as "SUPPLIER" and Immunicon Corporation, shall be referred to as
"Immunicon" herein. 

        Now,
Therefore, in consideration of the mutual covenants herein set forth, the parties hereto agree as follows: 

        1.    Definitions    

        For
purposes of this Agreement: 

        1.1   "Affiliate"
shall mean with respect to a party, an entity which, directly or indirectly, majority owns, or is majority owned by, or is under common majority ownership
with, that party. For the purposes hereof, a partnership shall be deemed an Affiliate if a party hereto is the managing partner or is a general partner and has an active and significant economic
interest therein. 

        1.2   "PRODUCTS"
shall mean component parts, subassemblies and associated spare parts listed in Schedule "C" or any other product or products that the
parties from time to time hereafter may mutually agree to add to this Agreement, which are supplied to Immunicon hereunder. The individual parts or subassemblies which comprise
these PRODUCTS and the processing and test instructions for each, are described in detail as specifications on drawings for part numbers provided to SUPPLIER and referenced in  APPENDIX "C".

        1.3   "TEST
REPORT" shall mean the actual measurements recorded on a paper printout upon the completion of test procedures indicated on Immunicon specifications for the
PRODUCTS tested prior to shipment. 

        1.4   "Schedule"
shall mean a document issued by Immunicon, which specifies "releases" for delivery of PRODUCT(S). 

        2.    Term/Appointment of SUPPLIER/Exclusivity    

        2.1   The
initial term of this Agreement shall continue for two (2) years following the Effective Date unless terminated earlier pursuant to the express terms of this
Agreement. This Agreement shall automatically renew for successive one-year terms unless Immunicon gives SUPPLIER written notice of its intent not to renew at least
ninety (90) days prior to the end of the then-current term. Subject to fulfillment of its obligations under the terms and conditions of this Agreement,
SUPPLIER shall produce and supply to Immunicon all of Immunicon's requirements of the PRODUCTS defined herein during the initial term of this Agreement and any renewal thereof, unless this Agreement
is terminated as permitted herein or the provisions of section 2.2 become applicable. In addition to the other obligations of SUPPLIER hereunder, SUPPLIER shall provide on time delivery of
quality PRODUCTS to Immunicon, time being of the essence under this Agreement. 

        2.2   In
the event SUPPLIER fails to supply Immunicon's requirements of PRODUCTS or fails to timely deliver quality PRODUCTS to Immunicon under section 2.1 at any time
while this Agreement is in effect, Immunicon shall, in addition to any other rights and remedies it may have arising from such failure and regardless of whether Immunicon exercises its right of
termination hereunder, have the right thereafter to obtain from any third party products substantially the same 

2

 

as
or similar to PRODUCTS in order to meet its requirements thereof. In the event Immunicon obtains such third party products under this section 2.2, SUPPLIER shall be relieved of its
obligation hereunder to supply Immunicon's requirements of PRODUCTS. 

        2.3   While
this Agreement is in effect and for a period of [**] years thereafter, SUPPLIER shall not develop, manufacture or sell, nor shall
SUPPLIER directly or indirectly assist any third party to develop, manufacture or sell, any products which are competitive with the PRODUCTS supplied to Immunicon by SUPPLIER under this Agreement,
without the prior express written consent of Immunicon. For purposes of this Agreement, a product shall be considered competitive with the PRODUCTS supplied to Immunicon under this Agreement if such
product is useful in the cellular diagnostics, cellular separation or cellular enrichment fields. 

        2.4   The
parties acknowledge that Immunicon is not obligated to buy any specific amount of PRODUCTS under this Agreement, except as set forth in Section 4.2 of this
Agreement. 

        3.    Agreement to Manufacture and Manufacturing Responsibilities    

        3.1   SUPPLIER
shall manufacture the PRODUCTS to the specifications and procedures provided to SUPPLIER by Immunicon. SUPPLIER also agrees to allow compliance with these
specifications and procedures to be audited by Immunicon's Quality Assurance / Supplier Development Group or other representatives of Immunicon, at Immunicon's request. It is further understood that
SUPPLIER shall have primary responsibility for management of its suppliers and the resolution of technical issues. Failure of SUPPLIER to meet such specifications and procedures supplied by Immunicon
shall be deemed a material breach of this Agreement. 

        3.2   SUPPLIER
shall notify Immunicon in writing prior to the implementation of any process change or the use of any manufacturing facility which differ from those processes
or facilities being used to produce PRODUCTS at the Effective Date of this Agreement. 

        3.3    Engineering Changes.    

        3.3.1   Immunicon
may request to SUPPLIER in writing (via its Engineering Change Order or "ECO" document) that SUPPLIER incorporate engineering changes to any
PRODUCT. An Immunicon ECO with a Immunicon Quality Assurance representative's signature is the only recognized communication of change for production released PRODUCTS. If the incorporation of such
changes is agreed between Immunicon and SUPPLIER, the PRODUCT pricing in SCHEDULES "B" and "C" shall be amended accordingly by mutual agreement of
Immunicon and SUPPLIER. SUPPLIER shall not unreasonably refuse to incorporate Immunicon's engineering changes in a PRODUCT when requested by Immunicon. A product transfer plan mutually agreed by
Immunicon and SUPPLIER shall describe how changes are to be controlled, the responsible parties named and how validation of the change will be handled. 

        3.3.2   Payment
of reasonable material scrap or other costs incurred by SUPPLIER due to an Engineering Change Order are the responsibility of Immunicon and are
payable net 30 days from the time of ECO implementation. 

	**
	Certain information in these exhibits has been omitted and will be filed separately with the Securities and Exchange Commission pursuant to a confidential
treatment request under 17 C.F.R. Sections 200.80(b)(4), 200.83 and 230.406.

3

 

        3.4    Testing.    SUPPLIER shall test PRODUCTS in accordance with the test procedures and specification procedures
supplied by Immunicon and mutually agreed upon. Any test equipment supplied to SUPPLIER by Immunicon or designed and fabricated by SUPPLIER for testing Immunicon PRODUCT shall be maintained and
calibrated by SUPPLIER at its expense. SUPPLIER shall modify such test equipment as engineering changes to the PRODUCT requested by Immunicon or mutually agreed upon process changes require. The
reasonable costs of such changes shall be at the expense of Immunicon. 

        3.5   Immunicon
shall have the right to add additional products to this Agreement upon acceptance by SUPPLIER, all of which added products shall become PRODUCTS as defined
herein. 

        3.6    Tooling.    Immunicon will solely own all tooling funded by Immunicon to produce PRODUCTS, and during the term
of this Agreement SUPPLIER shall use tooling exclusively for the manufacture of PRODUCTS. The cost of all such tooling shall be mutually agreed between Immunicon and SUPPLIER before ordering. SUPPLIER
shall use and maintain all Immuicon owned tooling with the same level of care it would for its own tooling. If major repair of tooling is due to causes other than SUPPLIER's neglect, misuse, or other
cause attributable to SUPPLIER, Immunicon will be responsible for the costs thereof, provided Immunicon is fully informed in advance of the necessity of incurring such costs and agrees to such costs. 

        3.7    Material Purchases and Supply Chain Management.    SUPPLIER is responsible for planning, purchasing, quality
assurance, and payment for all materials needed to satisfy SUPPLIER'S obligations under this Agreement. SUPPLIER shall have sole responsibility to resolve all material, technical and quality issues
related to sub-tier suppliers; provided, however, that Immunicon may, at its discretion, assist SUPPLIER in such resolution. 

        4.    Commercial Terms and Pricing    

        4.1    Purchase Orders.    Immunicon shall place its orders for PRODUCTS and spare PRODUCTS on Immunicon Purchase
Order forms which are substantially the same as the Purchase Order attached hereto in APPENDIX "A". The provisions printed on the reverse side of such
purchase orders shall be binding upon the parties and are incorporated herein by reference, and shall control except where they are inconsistent or in conflict with the provisions of this Agreement,
in which case the provisions of this Agreement shall govern and prevail. 

        4.2    Ordering and Forecasts.    Immunicon shall specify its expected requirements for PRODUCTS to be manufactured by
SUPPLIER and delivered to Immunicon under this Agreement by issuing a 12-month rolling forecast on a monthly basis. Immunicon will notify SUPPLIER of its delivery requirements using a
"schedule" document, which specifies "release" quantities with respect to
the then monthly commitment quantity or some other quantity to be mutually agreed. The "schedule" document will reference the Purchase Order. 

        This
12-month rolling forecast is divided into the following three (3) periods: 

Frozen period: 

        Within
this rolling period the delivery dates and quantities are fixed. The length of this Period will be four (4) weeks. 

        Immunicon
commits to receiving and not amending the specific weekly quantities within this rolling period, without prior agreement with SUPPLIER—only weekly quantities
outside this period can be subject to change. 

4

 

Variable period: 

        This
rolling period follows immediately after the frozen period. The length of this period will be for eight (8) weeks. During this variable period SUPPLIER is allowed to purchase
parts and, if necessary assemble PRODUCTS in order to meet the required delivery date of PRODUCTS. Immunicon is obliged to purchase these PRODUCTS  without a delivery date being determined. 

Informative period:

        This
period follows immediately after the variable period. The length of this period will be for the balance of the rolling twelve- (12) month period. During this period Immunicon
has no obligation to purchase any PRODUCT or parts. Immunicon's liability with respect to "long lead items" and/or "end of life items", outside the first two periods above (totaling twelve weeks),
will be honored in accordance with section 10 of this Agreement. 

        4.3    Pricing and Cost Reductions.    SUPPLIER shall sell to Immunicon PRODUCTS at a firm and fixed price per  SCHEDULE "B" for one
(1) year following the execution of this Agreement. Thereafter, both
parties agree to open book pricing during the remainder of the term of this Agreement, as defined in the structure shown in SCHEDULE "B". Immunicon may
require SUPPLIER to purchase materials from lower tier suppliers ("source controlled suppliers"). If the price of such lower tier supplied material (third party to SUPPLIER) changes from time to time,
the new price of material will be reflected in the pricing structure in "SCHEDULE B" as mutually agreed by Immunicon and SUPPLIER and a new PRODUCT
selling price will be placed in effect at a time that the new cost is incurred by SUPPLIER. 

        4.3.1    Sharing of Cost Savings.    SUPPLIER may at any time, suggest to Immunicon changes, however small, that will
result in improved performance, reliability or yield of PRODUCTS. SUPPLIER agrees to perform value engineering and value analysis with the goal of reducing the costs of PRODUCTS over the commercial
life of the PRODUCTS. If Immunicon decides to purchase additional tooling to increase production of assemblies of an existing design, the cost reductions that occur as a result of this activity will
be passed on to Immunicon upon implementation of the tooling and use of the parts in production. If Immunicon recommends any changes to an existing design that reduce costs, these cost reductions or
changes are to be reflected in a lower unit price. Changes that are suggested by SUPPLIER and accepted by Immunicon, shall upon implementation, be shared equally between both parties. 

        4.4    Packaging.    SUPPLIER shall package all PRODUCTS in suitable containers for protection during shipments by air
or ocean freight worldwide and for storage. Packaging shall be mutually agreed between Immunicon and SUPPLIER. A PRODUCTS transfer plan will reference the qualification requirements for packaging. 

        4.5            SUPPLIER will provide with each shipment of PRODUCTS a copy of the "TEST REPORT" for each
individual PRODUCT contained therein. 

        4.6    Immunicon Purchasing Rights.    It is understood and agreed that purchases under this Agreement, and in
furtherance thereof, may be made directly form SUPPLIER by Immunicon's' parent, affiliate or subsidiary companies, or other sources authorized by Immunicon in writing to SUPPLIER, and the provisions
contained herein shall be equally applicable to said purchases. 

        4.7   PAYMENT—SUPPLIER shall be paid pursuant to each invoice for PRODUCTS net
30 days following shipment of such PRODUCTS from the factory (Strongsville, OH). 

5

 

        5.    Quality, Workmanship, and Warranty    

        5.1   SUPPLIER
agrees to comply with Immunicon's Quality Assurance Procedures and Immunicon engineering documentation for all PRODUCTS. A Device History Record (DHR) is to be
maintained by SUPPLIER for assemblies of PRODUCTS. For the purposes of this Agreement, it is understood and agreed that these procedures are the only recognized forms of communicating the provisions
contained therein between Immunicon and SUPPLIER. A PRODUCTS transfer plan will be followed that will describe the criteria for acceptance and successful transfer of PRODUCTS. 

        5.2   Immunicon
is entitled to reject any PRODUCT received by Immunicon, its affiliate or subsidiary companies, or other sources, which fails to conform to the agreed upon
acceptance criteria whether such criteria are preliminary or final. SUPPLIER agrees to use its best effort and resources to immediately repair or replace any non-conforming PRODUCT within
30 days of receipt of returned material, provided that the component replacement time does not prohibit such a time period. All cost of shipment to and from SUPPLIER resulting from properly
rejected PRODUCTS found to be non-conforming shall be borne by SUPPLIER. 

        5.3    Return of goods.    In the case that Immunicon returns PRODUCTS to SUPPLIER for any reason, it is understood
that Immunicon will decontaminate these PRODUCTS or in the case that Immunicon is not capable of decontaminating these PRODUCTS shall remove all fluids and disposables associated therewith and tag the
PRODUCTS as Bio-Hazardous. All returned PRODUCTS shall have a Returned Material Authorization (RMA) number. RMA numbers shall be requested by Immunicon from SUPPLIER'S Customer Service
Representative for each PRODUCT to be returned, thereafter, within ten days after receipt of such number by Immunicon such PRODUCT will be shipped to SUPPLIER. Additionally, SUPPLIER agrees to issue
an RMA number to Immunicon for return of PRODUCTS within (72) hours of Immunicon's request. 

        5.4    Warranty.    SUPPLIER warrants to Immunicon that PRODUCT manufactured and supplied to Immunicon shall conform
to the Immunicon specifications and/or any other mutually agreed upon acceptance criteria and be free from defects in workmanship and process related material defects for a period of
(12) months after shipping date. For Immunicon source controlled parts the warranty period will be no longer than given by the applicable vendor. SUPPLIER warrants to Immunicon that the
PRODUCTS supplied to Immunicon hereunder shall (a) comply in all material respects with the specifications for such PRODUCTS as supplied by Immunicon and Immunicon's acceptance criteria for
such PRODUCTS and (b) be manufactured in accordance with Immunicon's Quality Assurance Procedures and all applicable Federal, state and local laws, rules and regulations, including Good
Laboratory Practices (as defined in Federal Register 21 CFR Part 58) and Good Manufacturing Practices (as defined in Federal Register 21 CFR Part 110). 

        Immunicon
shall perform initial warranty evaluation on the PRODUCTS and submit samples of returned PRODUCTS to SUPPLIER for its further evaluation and confirmation of defects of product
failure. Upon SUPPLIER confirmation, SUPPLIER shall replace, at its sole expense, the PRODUCT during the warranty period. Shipping charges to SUPPLIER for said defective PRODUCTS shall be paid by
SUPPLIER, and shall include but not be limited to, freight changes, time, and materials. 

        5.5            Immunicon shall have no obligation to pay for any PRODUCT that does not comply with the
specifications for such PRODUCT as supplied by Immunicon to SUPPLIER or with Immunicon's acceptance criteria or with the warranties contained herein. SUPPLIER's liability with respect to any claim
that a PRODUCT furnished hereunder to Immunicon does not meet the foregoing shall be limited to the replacement of such PRODUCT at 

6

 

SUPPLIER's
cost and expense, or a refund of the purchase price of such PRODUCT, SUPPLIER may elect. 

PRODUCTS
returned to SUPPLIER in which no defect due to SUPPLIER is found, shall be returned at the expense of Immunicon. SUPPLIER shall invoice Immunicon for costs incurred, to include but not be
limited to, freight changes, time, and materials. 

        5.6   Immunicon
at its option, shall have the right to source inspect any and all PRODUCTS at SUPPLIER's facility(s) prior to shipment by SUPPLIER to ensure conformity to
Immunicon's acceptance criteria, written specifications, test requirements, or other mutually agreed upon criteria. 

        6.    Spares Inventory    Immunicon shall provide a Recommended Spares List (RSL) for PRODUCTS and SUPPLIER shall
maintain an inventory of spares in accordance with the RSL sufficient while this Agreement is in effect to meet projected monthly requirements of such spares based on production leadtimes. Immunicon's
subsidiaries, affiliates, and other sources may order spares per the pricing listed in SCHEDULE C.

        SUPPLIER
agrees to provide all of the spares requirements for PRODUCTS for a period of no less than ten (10) years after delivery of the last PRODUCT to Immunicon hereunder.
SUPPLIER shall be relieved of this obligation upon Immunicon's execution of an agreement with another supplier for the supply of PRODUCTS substantially equivalent to the PRODUCTS covered hereunder. 

        7.    Transfer of Title/Transportation    Title to all PRODUCTS shall transfer to Immunicon on shipment of the PRODUCT
by SUPPLIER to Immunicon. Immunicon shall pay the cost and insurance of transportation and shall instruct SUPPLIER as to the method of transportation to be used for each delivery. 

        8.    Refurbishment    

        SUPPLIER
further agrees to refurbish/repair out-of-warranty PRODUCTS or in-warranty PRODUCTS containing defects not caused by SUPPLIER, based on
Immunicon's instructions to Immunicon's original specifications, including all test requirements or other mutually agreed upon requirements. The cost to refurbish such PRODUCTS shall be negotiated and
agreed between SUPPLIER and Immunicon in good faith based on SUPPLIER's normal overhead and profit rates and on the extent of labor and material required to restore the PRODUCTS to the original
Immunicon specifications. SUPPLIER shall provide Immunicon a written quotation for said refurbishment work within (15) business days of receiving returned PRODUCTS for evaluation. Immunicon at
its discretion shall indicate to SUPPLIER the shipping destination of such refurbished PRODUCTS. 

        9.    Force Majeure.    

        9.1   Failure
of either party to perform any of its obligations under this Agreement in whole or in part, shall be excused if such failure is the result of force majeure
including, but not limited to, flood, wind and lightning, insurrections, strikes, riots, war and warlike operations, terrorism, civil commotion, fires, explosions, accidents, the acts or orders of any
governmental agency, acts of the public enemy, and laws or regulations or restrictions of the governmental entity or of any agency or instrumentality thereof. 

        9.2   If
performance of this Agreement is excused pursuant to the foregoing section the party thus excused shall use reasonable efforts to perform, and the party excused from
performance shall resume performance with the utmost dispatch when such circumstances are avoided, removed or corrected. 

7

 

        9.3   If
the circumstances of force majeure last longer than sixty (60) days, the party which has not declared the force majeure shall have the right to terminate this
Agreement upon thirty (30) days prior written notice to other party. 

        10.    Termination    

        Immunicon
may terminate this Agreement, for any reason and without cause, on ninety-(90) days written notice to SUPPLIER. In the event of termination under this section, Immunicon shall
pay SUPPLIER for non-cancelable costs actually incurred by SUPPLIER with respect to its manufacture and/or production of that quantity of PRODUCTS which is the subject of a binding
purchase order placed pursuant to section 4.1/4.2 above but not yet shipped. Long lead and end of life purchased parts that SUPPLIER placed on order to meet Immunicon forecast schedule shall be
the liability of Immunicon. 

        10.2 In
the event that Immunicon wishes to terminate this Agreement, SUPPLIER, upon receipt of such written notice, shall stop work to the extent specified herein.
Immunicon's termination liability shall be limited to the following: 

        a.     Payment
for all PRODUCTS ordered and/or delivered to Immunicon and in-transit including finished PRODUCT in SUPPLIER's inventory prior to written notification
of Termination. 

        b.     Payment
for all "Work-in-Process" based on the current SUPPLIER rate structure for labor and material mark-up. 

        c.     Payment
for all non-cancelable material purchase orders for Immunicon PRODUCTS plus material mark-up. 

        10.3 In
the event SUPPLIER wishes to terminate this Agreement, SUPPLIER may do so upon twelve (12) months prior written notice to Immunicon; provided, however that
SUPPLIER shall continue to supply Production quantities of PRODUCTS to Immunicon to the extent that component parts and finished goods in SUPPLIER's inventory may permit and give its best efforts to
facilitate a smooth transition of supply of PRODUCTS to Immunicon's designated source for further supply of PRODUCTS as may be requested by Immunicon, including transfer of all pertinent process "know
how" and documentation, tools and fixtures, and test equipment and any other material relevant to the manufacture of PRODUCTS. 

        10.4 This
Agreement may be terminated at any time upon mutual written consent of the parties to this Agreement 

        10.5 This
Agreement may be terminated by either party (a) immediately upon notice to the other party in the event that such other party is in material breach of this
Agreement and such breach remains uncured for a period of thirty (30) days following notice to the breaching party, or (b) immediately upon notice to the other party in the event that
(i) such other party shall (A) apply for or consent to the appointment of, or the taking of possession by, a receiver, custodian, trustee or liquidator of itself or of all or a
substantial part of its property, (B) make a general assignment for the benefit of its creditors, (C) commence a voluntary case under the United States Bankruptcy Code, as now or
hereafter in effect (the "Bankruptcy Code"), (D) file a petition seeking to take advantage of any law (the "Bankruptcy Laws") relating to bankruptcy, insolvency, reorganization,
winding-up, or composition or readjustment of debts, (E) fail to controvert in a timely and appropriate manner, or acquiesce in writing to, any petition filed against it in any
involuntary case under the Bankruptcy Code, or (F) take any corporate action for the purpose of effecting any of the foregoing; or (ii) a proceeding or case shall be commenced against
such other party in any court of competent jurisdiction, seeking (A) its liquidation, reorganization, dissolution or winding-up, or the composition or readjustment of its debts,
(B) the appointment of 

8

 

a
trustee, receiver, custodian, liquidator or the like of the party or of all or any substantial part of its assets, or (C) similar relief under any Bankruptcy Laws, or (iii) an order,
judgment or decree approving any of the foregoing shall be entered and continue unstayed for a period of 60 days; or an (iv) order for relief against such other party shall be entered in
an involuntary case under the Bankruptcy Code. 

        The
termination or expiration of this Agreement shall neither release either party from the obligation to pay any sum that may be owing to the other, nor operate to discharge any
liability that had been incurred by either party prior to any such termination or expiration including, but not limited to, any obligation to deliver or pay for PRODUCTS or complete purchase orders
accepted hereunder. Neither party shall, by reason of the termination of this Agreement, be liable to the other for compensation, reimbursement or damages due to loss of profits on sales or
anticipated sales or losses due to expenditures, investments or commitments made in connection with this Agreement or the establishment, development or maintenance of the business or goodwill of
either party or on account of any cause whatsoever. 

        11.    Confidentiality/Patent Rights    

        Immunicon
and SUPPLIER have both signed a Confidentiality Agreement under separate cover (APPENDIX "B") and same shall become part of this
Agreement. The terms and conditions of the signed Confidentiality Agreement shall govern exchanges of information between the parties hereto and shall survive this Agreement. SUPPLIER acknowledges
that PRODUCTS contain proprietary technology of Immunicon and may be the subject of patents and patent applications that are owned by or licensed to Immunicon and/or its Affiliates. No right or
license is granted to SUPPLIER with respect to any such proprietary technology, patents or patent applications hereunder except the limited, nonexclusive, revocable right and license to utilize the
foregoing for the manufacture and sale of PRODUCTS to Immunicion under this Agreement. Upon termination of this Agreement, such license shall be null and void. The purchase by and transfer of title to
Immunicon of PRODUCTS hereunder, shall grant to Immunicon the non-revocable and fully-transferable right and license
under any intellectual property or other proprietary rights of SUPPLIER embodied in such PRODUCTS, to use and have used, sell and have sold, distribute and have distributed, and dispose of and have
disposed of, such PRODUCTS and components of such PRODUCTS, without restriction of any kind. 

        12.    Right of Inspection    

        12.1 Immunicon
shall have the right under normal business hours to visit SUPPLIER "s facilities to conduct evaluations and review the performance of SUPPLIER "s obligations
under this Agreement. Immunicon shall also have the right to meet with SUPPLIER personnel and review development, production, process, and quality records relevant to the subject matter in this
Agreement subject to the confidentiality Agreement signed under separate form between SUPPLIER and Immunicon. Immunicon shall provide reasonable notice to SUPPLIER prior to each such visit. 

        13.    Complete Agreement    

        13.1 The
terms and conditions of this Agreement shall supercede and replace any previous terms and conditions of any agreement or understanding between SUPPLIER and
Immunicon relating to the supply of PRODUCTS to Immunicon by SUPPLIER, whether written or oral, except for the terms and conditions of the Confidentiality Agreement referenced in sections 11 and 12 to
the extent not inconsistent herewith. 

        14.    Governing Law    

        14.1 The
construction, validity and performance of this Agreement shall be governed by the laws of the State of Delaware, without giving regard to its
choice-of-law rules. 

9

 

        15.    Indemnification    

        15.1 Immunicon
agrees, at its cost, to defend and hold SUPPLIER harmless from any claim by any person, firm, corporation or governmental unit which arises out of the
manufacture, sale or use of the PRODUCTS with respect to property damage/bodily injury only, except to the extent such claim is caused by or arises out of the intentional malfeasance or negligent acts
or omissions of SUPPLIER. 

        16.    Assignment:    Neither party may directly or indirectly assign or transfer this Agreement, in whole or on part,
to any third party without the other party's prior written consent, which consent shall not be unreasonably withheld or delayed. Notwithstanding the above, either Immunicon or SUPPLIER may assign its
rights and obligations hereunder to a subsidiary or Affiliate or to a purchaser of its business relating to the PRODUCTS without the prior written consent of the other. This Agreement shall be binding
upon and inure to the benefit of the parties hereto and their respective successors and permitted assigns. 

        17.    Severability:    In the event of any provision of this Agreement shall be deemed to be invalid, void, illegal,
or unenforceable, the remaining provisions hereof nevertheless will continue in full force and effect without being impaired or invalidated in any way. 

        18.    Notices    

        18.1 Any
notices from either party which affect this Agreement shall be in writing and sent by certified mail, fax or courier to the address of that party as set out below
or such other address as may from time to time have been notified in writing by either company in question to the other. 

        In
the case of notices to Immunicon Corporation: 

Immunicon Corporation

3401 Masons Mill Road, Suite 100

Huntingdon Valley, PA 19006-3574 For the attention of: Vice President of Engineering

With
a copy to 

Immunicon Corporation

3401 Masons Mill Road, Suite 100

Huntingdon Valley, PA 19006-3574

For the attention of: Chief Financial Officer

In
the case of notices to SUPPLIER 

Astro Instrumentation L.L.C.

13500 Darice Parkway

Strongsville, Ohio 44149

For the attention of:

Vice President / General Manager

        19.    Privity:    The relationship established between SUPPLIER and Immunicon shall be solely that of seller and
buyer, and neither party shall be in any way the agent or representative of the other party for any purpose whatsoever, and shall have no right to create or assume any obligation or responsibility of
any kind, whether express or implied, in the name of or on behalf of the of the party to bind the other party in any manner whatsoever. The status of the parties is as independent contractors, and
this Agreement does not create any partnership, association, or other business entity, nor shall anything herein be deemed to constitute either party an agent of the other, and neither party shall
make any statements or representations to the contrary by advertising, signs, letterheads, or otherwise. No contracts, commitments, statements, or representations made by or on behalf of either party
shall be binding in any respect on the other party. Unless specifically provided elsewhere herein, nothing in this 

10

 

Agreement
is intended to benefit any person or entity not a party hereto. This Agreement shall be binding upon and inure to the benefit of the parties hereto and their respective successors and
permitted assigns. 

        20.    Validity of Agreement Signed in Counterpart    

        This
Agreement may be signed in counterparts, each of which shall be an original, but all of which shall be deemed to be one and the same instrument, and shall be valid and binding when
so signed. 

        21.   The
article, section and paragraph headings contained in this Agreement are for reference purposes only and shall not affect in any way the meaning or interpretation of
this Agreement. 

        22.   The
failure of either party to enforce at any time for any period any provision hereof shall not be construed to be a waiver of such provision or of the right of such
party thereafter to enforce each such provision, nor shall any single or partial exercise of any right or remedy hereunder preclude any other or further exercise thereof or the exercise of any other
right or remedy. Remedies provided herein are cumulative and not exclusive of any remedies provided at law. 

        23    Any
controversy or claim arising out of or relating to this Agreement shall be resolved by arbitration before a single arbitrator in accordance with the Commercial
Arbitration Rules of the American Arbitration Association ("AAA") then pertaining (available at www.adr.org), except where those rules conflict with this provision, in which case this provision
controls. Any court with jurisdiction shall enforce this clause and enter judgment on any award. The arbitrator shall be selected within twenty business days from commencement of the arbitration from
the AAA's National Roster of Arbitrators pursuant to agreement or through selection procedures administered by the AAA. Within 45 days of initiation of arbitration, the parties shall reach
agreement upon and thereafter follow procedures, including limits on discovery, assuring that the arbitration will be concluded and the award rendered within no more than eight months from selection
of the arbitrator or, failing agreement, procedures meeting such time limits will be designed by the AAA and adhered to by the parties. The arbitration shall be held in Philadelphia, Pennsylvania and
the arbitrator shall apply the substantive law of Delaware, except that the interpretation and enforcement of this arbitration provision shall be governed by the Federal Arbitration Act. Prior to
commencement of arbitration, emergency relief is available from any court to avoid irreparable harm. THE ARBITRATOR SHALL NOT AWARD EITHER PARTY PUNITIVE, EXEMPLARY, MULTIPLIED OR CONSEQUENTIAL
DAMAGES, OR ATTORNEYS FEES OR COSTS. Prior to commencement of arbitration, the parties must attempt to mediate their dispute using a professional mediator from AAA, the CPR Institute for Dispute
Resolution, or like organization selected by agreement or, absent agreement, through selection procedures administered by the AAA. Within a period of 45 days after the request for mediation,
the parties agree to convene with the mediator, with business representatives present, for at least one session to attempt to resolve the matter. In no event will mediation delay commencement of the
arbitration for more than 45 days absent agreement of the parties or interfere with the availability of emergency relief. 

11

 

        IN
WITNESS WHEREOF, the parties have caused their respective duly authorized representatives to sign this Agreement in counterparts, putting this Agreement in effect as of the date of
both parties' signatures. 

	ASTRO INSTRUMENTATION, LLC	 	IMMUNICON CORPORATION
	

/s/ DUANE STIERHOFF
 Signed by:

Duane Stierhoff

Vice President / General Manager

Astro Instrumentation	
 	

/s/ [ILLEGIBLE]
 Signed by:
	

11/19/02
 Dated:	
 	

    
 Dated:

12

 
 
 

SCHEDULE "A"    
    
    PRE-PRODUCTION PRICING    
    

        Pre-Production pricing is for [**] as follows: 

Material

Cost
of Material × [**] markup 

Labor

[**]
at a rate of [**] 

Example:

[**]

[**]

[**]

[**]

	**
	Certain information in these exhibits has been omitted and will be filed separately with the Securities and Exchange Commission pursuant to a confidential
treatment request under 17 C.F.R. Sections 200.80(b)(4), 200.83 and 230.406.

13

 
 
 

SCHEDULE "B"    
    
    PRODUCTION PRICING    
    

	PART NUMBER
 
	 	DESCRIPTION
	 	QUANTITY
	 	UNIT PRICE

	TBD	 	TBD	 	TBD	 	TBD

14

 
 
 

SCHEDULE "C"    
    
    SPARES PRICING    
    

	PART NUMBER
 
	 	DESCRIPTION
	 	QUANTITY
	 	UNIT PRICE

	TBD	 	TBD	 	TBD	 	TBD

15

 
 
 

APPENDIX "A"    
    
    IMMUNICON PURCHASE ORDER
  STANDARD TERMS AND CONDITIONS    
    

COPY OF IMMUNICON PURCHASE ORDER TO BE ATTACHED  

16

 
  
 

    APPENDIX "B"    
    
    IMMUNICON / ASTRO CONFIDENTIALITY AGREEMENT    
    

17

QuickLinks

Exhibit 10.31

SCHEDULE "A" PRE-PRODUCTION PRICING

SCHEDULE "B" PRODUCTION PRICING

SCHEDULE "C" SPARES PRICING

APPENDIX "A" IMMUNICON PURCHASE ORDER STANDARD TERMS AND CONDITIONS

APPENDIX "B" IMMUNICON / ASTRO CONFIDENTIALITY AGREEMENT

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