Document:

Form of senior subordinated convertible demand promissory note

 Exhibit 10.7 
 THIS NOTE HAS BEEN, AND THE SHARES OF COMMON STOCK OR NEW SECURITIES WHICH MAY BE RECEIVED PURSUANT TO THE CONVERSION OF THIS NOTE WILL BE, ACQUIRED SOLELY FOR INVESTMENT AND NOT WITH A VIEW TO, OR FOR
RESALE IN CONNECTION WITH, ANY DISTRIBUTION THEREOF. NEITHER THIS NOTE NOR SUCH SHARES OF COMMON STOCK OR NEW SECURITIES HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”), OR QUALIFIED UNDER ANY STATE
SECURITIES LAWS. SUCH SECURITIES MAY NOT BE SOLD OR OFFERED FOR SALE IN THE ABSENCE OF SUCH REGISTRATION OR QUALIFICATION OR AN OPINION OF COUNSEL IN FORM AND SUBSTANCE REASONABLY SATISFACTORY TO THE COMPANY THAT SUCH DISPOSITION IS EXEMPT FROM THE
REGISTRATION REQUIREMENTS OF THE ACT AND ANY REGISTRATION OR QUALIFICATION REQUIREMENTS UNDER APPLICABLE STATE SECURITIES LAWS. 
 THIS NOTE IS
SUBJECT TO AN INTERCREDITOR AND SUBORDINATION AGREEMENT DATED AS OF MAY 28, 2010 AMONG THE ADMINISTRATIVE AGENT NAMED THEREIN AND THE PURCHASERS NAMED THEREIN (INCLUDING THE HOLDER), AND ACKNOWLEDGED BY THE COMPANY WHICH, AMONG OTHER THINGS,
SUBORDINATES THE COMPANY’S OBLIGATIONS TO THE PURCHASER TO THE COMPANY’S OBLIGATIONS TO THE SENIOR LENDERS AS FURTHER DESCRIBED THEREIN. 
 RIB-X PHARMACEUTICALS, INC. 
 Senior Subordinated Convertible Demand
Promissory Note (the “Note”) 
  

			
	$             (the “Principal Amount”)	  	New York, NY
		  	November     , 2010

 Rib-X Pharmaceuticals, Inc., a Delaware corporation (the “Company”), for value received,
hereby promises to pay to                      or its assigns (collectively, the “Holder”) the Principal Amount together with
interest (computed on the basis of a 365-day year for the actual number of days elapsed) accruing daily and compounding quarterly from the date hereof on the unpaid balance of the Principal Amount from time to time outstanding at the rate of ten
percent (10%) per annum (the “Interest”) until the Principal Amount and Interest are paid in full or converted as provided herein. Capitalized terms used herein but not defined shall have the meanings given to such terms in the
Senior Subordinated Convertible Demand Promissory Note Purchase Agreement (the “Note Purchase Agreement”), dated as of May 28, 2010, by and among the Company and the Purchasers (as defined therein). It is acknowledged that the
Senior Subordinated Convertible Demand Promissory Notes issued pursuant to the Note Purchase Agreement, of which this Note is one, are being issued at the Third Closing in an aggregate amount of approximately $4,100,000 (such Senior Subordinated
Convertible Demand Promissory Notes, the “Third Closing Notes,” and the holders of such notes, collectively, the “Noteholders”). 

 Subject to Section 2 of this Senior Note, the Principal Amount and the Interest
thereon, unless previously converted or repaid as provided herein, shall be due and payable by the Company in cash on November 19, 2015 (the “Maturity Date”). Payments hereunder are to be made without defense, setoff,
counterclaim or recoupment in lawful money of the United States of America in same day or immediately available funds to the account of the Holder specified from time to time by the Holder to the Company. 

Subject to any applicable notice periods, all parties to this Senior Note, including the Company and any sureties, endorsers, or
guarantors, hereby waive protest, presentment, notice of dishonor, and notice of acceleration of maturity and agree to continue to remain bound for the payment of the Principal Amount, the Interest and all other sums due under this Senior Note
notwithstanding any change or changes by way of release, surrender, exchange, modification or substitution of any security for this Senior Note or by way of any extension or extensions of time for the payment of the Principal Amount and the Interest
and all such parties waive all and every kind of notice of such change or changes and agree that the same may be without notice or consent of any of them. 
 Following an Event of Default (as defined herein), the Noteholders who hold Senior Notes representing at least a majority of the aggregate principal amount owed by the Company pursuant to the then
outstanding Senior Notes (the “Senior Subordinated Majority”) may (i) elect to pursue the rights of the Noteholders under this Senior Note and all other Senior Notes and (ii) collectively employ an attorney to enforce
their rights and remedies under this Senior Note and all other Senior Notes and the Company and any surety, guarantor or endorser of this Senior Note hereby agree to pay to the Noteholders’ reasonable attorneys’ fees, plus all other
reasonable expenses incurred by the Noteholders in exercising any such rights and remedies. The rights and remedies of the Noteholders as provided in this Senior Note and all other Senior Notes shall be cumulative and each such right or remedy may
be pursued singly, successively, or together against any other funds, property or security held by the Noteholders for payment or security, in the sole discretion of the Senior Subordinated Majority. The failure to exercise any such right or remedy
shall not be a waiver or release of such rights or remedies or the right to exercise any of them at another time. 
 As used
herein, the term “Base Conversion Price” shall mean the Conversion Price (as defined in, and as adjusted pursuant to, the Company’s Sixth Amended and Restated Certificate of Incorporation (the “Charter”)) of
the Company’s Series C Preferred Stock; provided, however, if at any time there are no longer any shares of the Company’s Series C Preferred Stock outstanding, the Base Conversion Price shall thereafter be adjusted as if one
(1) share of Series C Preferred Stock continued to be outstanding. 
  

	1.	Conversion. 

  

	 	(a)	 In Connection With a Drag-Along Event. Subject to Sections 1(b) and 1(c) below, in the event of any transaction (including, without limitation,
any change of control transaction, joint venture, partnership, liquidation or Repayment Event (as defined herein)) approved by the Senior Eligible Securities Majority (as defined in the Charter), the Senior Subordinated Majority shall have the
right, but not the obligation, to elect to convert all or any portion of the amount then 

  
 -2-

	 	
outstanding under this Senior Note including any accrued but unpaid Interest (the “Outstanding Amount”) (and a corresponding portion of the Outstanding Amounts under all other
Senior Notes) into the number of shares of common stock of the Company, par value $0.001 per share (“Common Stock”), that is equal to (i) the Outstanding Amount divided by (ii) the lowest of (x) the Base Conversion
Price as of the date of such conversion, (y) the Equity Financing Conversion Price (as defined herein) for the most recent offering of New Securities (as defined herein) and (z) the IPO Conversion Price (as defined herein).

  

	 	(b)	In Connection With an Equity Financing. In the event that the Company consummates any financing pursuant to which the Company or any affiliate thereof issues
equity securities, including without limitation, any security convertible or exchangeable into equity securities of the Company, which shall exclude for this purpose (i) any equity securities (and any security convertible or exchangeable into
equity securities) of the Company issued upon conversion of the Junior Notes or the Senior Notes or upon exercise or conversion of the Existing Warrants or Warrants and (ii) any equity securities issued or issuable to officers, founders,
employees or directors of, or consultants to, the Company pursuant to a stock purchase or option plan or other compensatory stock arrangements existing as of May 28, 2010 or as otherwise approved by the Board of Directors of the Company (the
“New Securities”) prior to the Maturity Date, the Senior Subordinated Majority shall have the right, but not the obligation, to elect to convert all or any portion of the Outstanding Amount under this Senior Note (and a
corresponding portion of the Outstanding Amounts under all other Senior Notes) into the number of New Securities that is equal to (A) the Outstanding Amount being converted under this Senior Note (and the corresponding Outstanding Amounts being
converted under all other Senior Notes) divided by (B) the lesser of (1) the Base Conversion Price as of the date of such conversion and (2) thirty-three percent (33%) of the price per New Security at which the New Security is
sold to investors in the financing (the “Equity Financing Conversion Price”). 

  

	 	(c)	In Connection With an Initial Public Offering. In the event that the Company consummates an initial public offering of its Common Stock (the
“IPO”) prior to the Maturity Date, the Senior Subordinated Majority shall have the right, but not the obligation, to elect to convert all or any portion of the Outstanding Amount under this Senior Note (and a corresponding portion
of the Outstanding Amounts under all other Senior Notes) into the number of shares of Common Stock that is equal to (1) the Outstanding Amount being converted under this Senior Note (and the corresponding Outstanding Amounts being converted
under all other Senior Notes) divided by (2) the lesser of (y) Base Conversion Price as of the date of such conversion and (z) thirty-three percent (33%) of the amount per share for which the Company issues securities in the IPO
(the “IPO Conversion Price”). 

  

	 	(d)	Mechanics of Conversion. 

  
 -3-

	 	(i)	In connection with any conversion of the Senior Note pursuant to this Section 1, the Holder shall provide notice to the Company, which shall state such
Holder’s name or the names of his or its nominees in which such Holder wishes the shares of Common Stock or the New Securities to be issued upon conversion. Promptly following such conversion the Company shall update the books and records of
the Company to evidence the issuance of the applicable shares of Common Stock or New Securities to the Holder. 

  

	 	(ii)	Immediately upon any conversion of the Senior Note pursuant to this Section 1, this Senior Note shall no longer be deemed to be outstanding and all rights
of the holder with respect to this Senior Note shall immediately cease and terminate, except the right of the holder to receive the applicable shares of Common Stock or New Securities to which it is entitled as a result of such conversion.

  

	 	(iii)	The Company shall pay any and all issue and other taxes that may be payable in respect of any issuance or delivery of the applicable shares of Common Stock or New
Securities upon any conversion of this Senior Note pursuant to this Section 1. The Company shall not, however, be required to pay any tax which may be payable in respect of any transfer involved in the issuance and delivery of the
applicable shares of Common Stock or New Securities in a name other than that of the registered Holder of this Senior Note, and no such issuance or delivery shall be made unless and until the person or entity requesting such issuance has paid to the
Company the amount of any such tax or has established, to the satisfaction of the Company, that such tax has been paid. 

  

	 	(iv)	Any conversion hereunder of a portion of, but not all, the Senior Notes shall be pro rata among the Holders based on the Outstanding Amount held by each Holder.

  

	 	(f)	Reservation of Common Stock. During the period within which this Senior Note may be converted pursuant to this Section 1, the Company shall at all
times have authorized and reserved for issuance a sufficient number of shares of its Common Stock to provide for the conversion of the then Outstanding Amount. 

 

	2.	Repayment. 

  

	 	(a)	 Upon a Change of Control or Liquidation. In the event of (a) any liquidation, dissolution or winding up of the affairs of the Company,
(b) any consolidation, merger or other business combination of the Company (other than a consolidation, merger, or combination in which the stockholders of the Company immediately prior to the transaction possess more than fifty percent
(50%) of the voting securities of the surviving or resulting entity immediately after the transaction), (c) any sale or disposition of a majority of the Company’s equity interests (calculated on an as-converted basis) to any person or
entity who is not an 

  
 -4-

	 	
equityholder of the Company as of the date hereof, (d) any sale, license or disposition of all or substantially all of the assets of the Company, (e) any Public Company Merger or
(f) any other event in which the Series B and Series C Liquidation Preference (as defined in the Charter) would be payable to the holders of Series B Preferred Stock of the Company and Series C Preferred Stock of the Company (each a
“Repayment Event”), upon the written election of the Senior Subordinated Majority delivered to the Company the Holder shall automatically be entitled to receive, in full satisfaction of the Company’s repayment obligations under
this Senior Note, the greater of (i) the sum of (y) three and one-half times (3.5x) the Principal Amount plus (z) any then accrued but unpaid Interest and (ii) the amount that the Holder would be entitled to receive
if the Outstanding Amount converted into shares of Common Stock immediately prior to the Repayment Event at the lesser of (1) Base Conversion Price as of the date of such Repayment Event and (2) thirty-three percent (33%) of the fair
market value of a share of Common Stock at the time of the Repayment Event. It is understood and agreed that the Holder’s rights under this Section 2(a) shall survive any Repayment Event as to which the Senior Subordinated Majority does
not elect to exercise its right to repayment pursuant to this Section 2(a), with such changes to the defined term “Company” as are necessary to reflect structural changes resulting from such Repayment Event. In connection with any
Repayment Event that is a Public Company Merger, the Holder may elect to receive any of the payments contemplated by this Section 2(a) either in (A) cash, (B) securities issued by the surviving entity in connection with such Public
Company Merger (which securities issued by the surviving entity shall be valued based on the price per such security (or value per such security) in such Public Company Merger) or any combination of the foregoing (A) and (B). “Public
Company Merger” shall mean any merger of the Company with or into any other entity a result of which is that shares of common stock or equity securities of the surviving entity (or an affiliate thereof) received by the holders of securities of
the Company pursuant to such merger are listed on the New York Stock Exchange or the Nasdaq Stock Market or other stock exchange or listing system, or trade on any electronic quotation system, “Pink Sheets”, “OTCBB” or any
similar system. 

  

	 	(b)	Upon Demand. Upon the written election of the Senior Subordinated Majority, given following the earlier of (i) March 31, 2011 and (ii) the date on
which the Company enters into an exclusive product licensing transaction which provides at least $30,000,000 in up-front net cash proceeds to the Company, the Company shall promptly (and in any event within ten (10) business days of receipt of
such notice) repay the Outstanding Amount under this Senior Note and the corresponding Outstanding Amounts under all other Senior Notes. All such repayments shall be made pro rata among the Senior Notes based on the amounts then outstanding under
each such Senior Note. 

  

	 	(c)	No Prepayment. Except as contemplated by this Section 2, in no event shall the Company have the right or the obligation to repay any portion of the
Principal Amount or any Interest thereon or any portion of the amounts owed by the Company under any other Senior Note prior to the Maturity Date. 

  
 -5-

	3.	Restrictions on Transfer. This Senior Note and the equity interests into which the Senior Note may be converted, shall not be assigned, sold, pledged,
transferred or otherwise disposed of except in compliance with the terms of the Third Amended and Restated Stockholders Agreement, dated as of June 8, 2006, by and among the Stockholders (as defined therein) and the Company, as amended to date
(as so amended, the “Stockholders Agreement”) and only with the prior written consent of the Senior Subordinated Majority. For purposes of Section 3 and Section 4 of the Stockholders Agreement, the Holder
shall be deemed to hold the number of shares of Common Stock into which this Senior Note could be converted pursuant to Section 1. Any shares of Common Stock or New Securities issuable upon a conversion pursuant to Section 1
shall be subject to the terms and conditions of the Stockholders Agreement that are applicable to the Holder. 

  

	4.	Default. This Senior Note and all amounts due hereunder shall become immediately due and payable in cash at the election of the Senior Subordinated Majority upon
the occurrence at any time of any of the following events of default (individually, an “Event of Default” and collectively, “Events of Default”): 

 

	 	(a)	default in the payment when due of any portion of the Principal Amount or any Interest thereon; 

 

	 	(b)	the liquidation, termination of existence, dissolution or the appointment of a receiver or custodian for the Company or any part of its property if such appointment is
not terminated or dismissed within thirty (30) days; 

  

	 	(c)	the institution against the Company or any endorser or guarantor of this Senior Note of any proceedings under the United States Bankruptcy Code or any other federal or
state bankruptcy, reorganization, receivership, insolvency or other similar law affecting the rights of creditors generally, which proceeding is not dismissed within thirty (30) days of filing; 

 

	 	(d)	the institution by the Company or any endorser or guarantor of this Senior Note of any proceedings under the United States Bankruptcy Code or any other federal or state
bankruptcy, reorganization, receivership, insolvency or other similar law affecting the rights of creditors generally or the making by the Company or any endorser or guarantor of this Senior Note of a composition or an assignment or trust mortgage
for the benefit of creditors; 

  

	 	(e)	the material breach of any covenant set forth in the Note Purchase Agreement or this Senior Note which breach remains uncured ten (10) days after written notice
thereof by any Noteholder to the Company; 

  

	 	(f)	the occurrence of an Event of Default under the Junior Notes; 

  

	 	(g)	the failure of any of the Company’s representations or warranties set forth in Article II of the Note Purchase Agreement to be true and correct (i) in all
respects on the Initial Closing Date (as defined in the Note Purchase Agreement) or (ii) in all material respects on each Subsequent Closing Date (as defined in the Note Purchase Agreement); or 

  
 -6-

	 	(h)	the occurrence of any event upon which, whether with the giving of notice, the passage of time or otherwise, would allow the Holder or holders of any indebtedness of
the Company or any of its subsidiaries to accelerate or otherwise demand repayment or repurchase prior to the scheduled maturity thereof of any such indebtedness or the acceleration of any such indebtedness. 

Upon the occurrence of an Event of Default, the Holder shall have then, or at any time thereafter, all of the rights and remedies
afforded by the Uniform Commercial Code as from time to time in effect in the State of Delaware or afforded by other applicable law. 
  

	5.	General. 

  

	 	(a)	Successors and Assigns. This Senior Note, and the obligations and rights of the Company hereunder, shall be binding upon and inure to the benefit of the Company,
the Holder, and their respective heirs, successors and permitted assigns. 

  

	 	(b)	Recourse. Recourse under this Senior Note shall be to the Company and its assets only, and in no event to the officers, directors or shareholders of the Company.

  

	 	(c)	Changes. Changes in or additions to this Senior Note may be made or compliance with any term, covenant, agreement, condition or provision set forth herein may be
omitted or waived (either generally or in a particular instance and either retroactively or prospectively) upon written consent of the Company and the Senior Subordinated Majority and shall not, for the avoidance of doubt, separately require the
consent of the Holder; provided, however, any amendment modification or waiver of a provision of the Senior Notes that by its terms treats the Holder in a materially different and adverse manner relative to the other Noteholders shall
not be binding as to the Holder unless the Holder consents in writing to the amendment, modification or waiver; provided, further, that no such amendment, waiver or consent shall: (i) reduce the principal amount outstanding
hereunder without the Holder’s written consent, or (ii) reduce the rate of interest hereof without the Holder’s written consent. 

  

	 	(d)	Governing Law. This Senior Note shall be governed by and construed in accordance with the law of the State of Delaware, excluding the body of law relating to
conflict of laws. Notwithstanding anything to the contrary contained herein, in no event may the effective rate of interest collected or received by the holder hereof exceed that which may be charged, collected or received by the holder under
applicable law. 

  

	 	(e)	 Notices. All notices, requests, consents and demands shall be made in writing and shall be mailed postage prepaid, or delivered by hand, to the
Company at the Company’s principal offices or to the Holder at the address of the Holder set forth in the Note Purchase Agreement or to such other address as may be furnished in writing to the other party hereto, and in addition may be
delivered by telex, telecopy, electronic mail or facsimile transmission. All notices, requests, consents and other 

  
 -7-

	 	
communications hereunder shall be deemed to have been given either (i) if by hand, at the time of the delivery thereof to the receiving party at the address of such party set forth above,
(ii) if made by telex, telecopy, electronic mail or facsimile transmission, at the time that receipt thereof has been acknowledged by electronic confirmation or otherwise, (iii) if sent by overnight courier, on the next business day
following the day such notice is delivered to the courier service, or (iv) if sent by registered or certified mail, on the 3rd business day following the day such mailing is made. 

 

	 	(f)	Jurisdiction. THE COMPANY AGREES THAT ANY SUIT FOR THE ENFORCEMENT OF THIS SENIOR NOTE, THE NOTE PURCHASE AGREEMENT OR ANY OTHER RELATED DOCUMENT MAY BE BROUGHT
IN THE COURTS OF THE STATE OF NEW YORK OR ANY FEDERAL COURT SITTING THEREIN AND CONSENTS TO THE NONEXCLUSIVE JURISDICTION OF SUCH COURTS AND SERVICE OF PROCESS IN ANY SUCH SUIT BEING MADE UPON THE COMPANY AT ITS PRINCIPAL OFFICES. THE COMPANY HEREBY
WAIVES ANY OBJECTION THAT IT MAY NOW OR HEREAFTER HAVE TO THE VENUE OF ANY SUCH SUIT OR ANY SUCH COURT OR THAT SUCH SUIT IS BROUGHT IN AN INCONVENIENT COURT. 

 

	 	(g)	Trial by Jury. The Company hereby waives its right to a jury trial with respect to any action or claim arising out of any dispute in connection with this Note,
any rights or obligations hereunder or the performance of such rights and obligations. 

  

	 	(h)	To the extent permitted by applicable law, the Company shall not assert, and hereby waives, any claim against any Noteholder and their respective affiliates, directors,
employees, attorneys, agents or sub-agents, for special, indirect, consequential or punitive damages arising out of, in connection with, as a result of or related to, this Note, the transactions contemplated hereby or thereby, the Loan or the use of
the proceeds thereof. 

 [Remainder of Page Intentionally Left Blank] 

  
 -8-

 IN WITNESS WHEREOF, this Note has been executed and delivered on the date first
above written by the duly authorized representative of the Company. 
  

			
	RIB-X PHARMACEUTICALS, INC.
		
	By:	 	  

	Name: Mark Leuchtenberger
	Title: President and Chief Executive OfficerSenior subordinated convertible demand promissory note

 Exhibit 10.8 
 EXECUTION VERSION 
 RIB-X PHARMACEUTICALS, INC. 

SENIOR SUBORDINATED CONVERTIBLE DEMAND PROMISSORY NOTE 
 PURCHASE AGREEMENT 
 MAY 28, 2010 

 SENIOR SUBORDINATED CONVERTIBLE DEMAND 

PROMISSORY NOTE PURCHASE AGREEMENT 
 THIS SENIOR SUBORDINATED CONVERTIBLE DEMAND PROMISSORY NOTE PURCHASE AGREEMENT (this “Agreement”), dated as of May 28, 2010, is entered into by and among Rib-X Pharmaceuticals, Inc.,
a Delaware corporation (the “Company”) and those persons or entities listed on Schedule 1.01 to this Agreement (each, a “Purchaser” and collectively, the “Purchasers”). 

RECITALS 

WHEREAS, the Company has issued Subordinated Convertible Promissory Senior Notes (the “Junior Notes”) and
warrants (the “Existing Warrants”) pursuant to a Subordinated Convertible Senior Note Purchase Agreement, dated as of January 7, 2009, between the Company and the Purchasers named therein (the “Junior Note Purchase
Agreement”); 
 WHEREAS, the Company desires to issue to the Purchasers, and the Purchasers desire to purchase
from the Company, Senior Subordinated Convertible Demand Promissory Notes, the form of which is attached hereto as Exhibit A (the “Senior Notes”), in accordance with the terms and provisions of this Agreement; 

WHEREAS, the Purchasers hold Junior Notes representing at least sixty percent (60%) of the aggregate principal amounts of the
outstanding Junior Notes, and constitute the Junior Majority (as defined herein); and 
 WHEREAS, the Company and the
Purchasers acknowledge that the issuance of the Senior Notes and the Warrants (as defined herein) is subject to Article Fourth, Section B.3(d)(iii)(D) of the Sixth Amended and Restated Certificate of Incorporation of the Company (as the same may be
amended from time to time hereafter, the “Charter”) and the Senior Notes and the Warrants constitute Additional Shares of Common Stock (as defined in the Charter). 

NOW, THEREFORE, in consideration of the foregoing and the mutual representations, warranties and covenants herein contained, the
parties hereto hereby agree as follows: 
 ARTICLE I 
 NOTES 
 Section 1.01. Purchase and Delivery of the Senior Notes. Subject to
the terms and conditions of this Agreement, at each Closing (as defined herein), the Company hereby agrees to issue to each Purchaser, and each Purchaser (severally and not jointly) hereby agrees to purchase from the Company, (a) a Senior Note
having a principal amount as set forth opposite the name of such Purchaser on Schedule 1.01 hereto in the column labeled “Purchase Price” for such Closing (the “Purchase Price”) and (b) Warrants, the form
of which is attached hereto as Exhibit B, to purchase a number of shares (rounded to the nearest whole number) of Common Stock determined by multiplying such Purchase Price by .30 and dividing the
result by $0.6189 (collectively, the “Warrants”). Each Purchaser acknowledges that the Senior Notes purchased by such Purchaser at any Closing and therefore the Purchase Price that will be released from escrow and the Special
Account (as defined herein) to the Company may be adjusted with the 

 
consent of the Senior Eligible Securities Majority (as defined herein); provided, however, that no such adjustment shall change the percentage of the Senior Notes issued at such
Closing purchased by such Purchaser and in no event shall such Purchaser be required to purchase more Senior Notes than the “Aggregate Purchase Price” specified for such Purchaser on Schedule 1.01 hereto. 

Section 1.02. Closings. 
 (a) The first purchase and issuance of Senior Notes and Warrants shall take place on the date hereof or the first date thereafter on which the conditions set forth in Section 5.01 are satisfied (the
“First Closing”). Unless previously cancelled pursuant to the terms of this Agreement: (i) the second purchase and issuance of Senior Notes and Warrants shall take place on August 27, 2010 subject to the consent of the
Senior Eligible Securities Majority or on such other date as the Company and the Senior Eligible Securities Majority shall agree (the “Second Closing”); (ii) the third purchase and issuance of Senior Notes and Warrants shall
take place on November 26, 2010 subject to the consent of the Senior Eligible Securities Majority or on such other date as the Company and the Senior Eligible Securities Majority shall agree (the “Third Closing”); and
(iii) the fourth purchase and issuance of Senior Notes and Warrants shall take place on February 28, 2011 subject to the consent of the Senior Eligible Securities Majority or on such other date as the Company and the Senior Eligible
Securities Majority shall agree (the “Fourth Closing”). The First Closing, Second Closing, Third Closing and Fourth Closing are each sometimes referred to herein as a “Closing” and together as the
“Closings.” The Closings other than the First Closing are each sometimes referred to herein as a “Subsequent Closing” and together as the “Subsequent Closings.” Notwithstanding anything herein to
the contrary, the Senior Eligible Securities Majority shall have the right at any time prior to any Subsequent Closing to accelerate the purchase and issuance of all or any portion of the Senior Notes and Warrants. Any such acceleration shall be
(i) pro rata among the Purchasers based on the amount of Senior Notes remaining to be purchased by each and (ii) applied against the Senior Notes and Warrants scheduled to be purchased at the next succeeding Subsequent Closings. In no
event shall the total amount of Senior Notes and Warrants exceed the maximum amount of Senior Notes and Warrants to be purchased hereunder. 
 (b) At the First Closing, (i) the Company shall issue and deliver to each Purchaser a Senior Note in an original principal amount equal to such Purchaser’s Purchase Price for the First Closing,
(ii) the Company shall issue and deliver to each Purchaser such Purchaser’s Warrant for the First Closing, (iii) each Purchaser other than Radius (as defined in the Charter, “Radius”) shall deliver to Webster Bank, N.A. as
escrow agent (the “Escrow Agent”), pursuant to the Escrow Agreement attached as Exhibit E hereto, such Purchaser’s aggregate Purchase Price for all Closings by wire transfer of immediately available funds to the account
designated in writing by the Escrow Agent and Radius shall deliver to the Company Radius’ aggregate Purchase Price for all Closings by wire transfer of immediately available funds to a segregated account designated in writing by the Company
(the “Special Account”) and (iv) the Escrow Agent shall deliver to the Company each Purchaser’s (other than Radius’) Purchase Price for the First Closing and the Company shall transfer Radius’ Purchase Price for
the First Closing from the Special Account to the Company’s general operating account. Notwithstanding the foregoing, if Vox Equity Partners II, L.P (“Vox”) does not deliver its aggregate Purchase Price to the Escrow Agent at
the First Closing, then (i) on or before June 2, 2010, Vox shall deliver (a) to 

  
 - 2 -

 
the Company (to an account designated by the Company), by wire transfer of immediately available funds, Vox’s Purchase Price in respect of the First Closing and (b) to the Escrow Agent
(to the account designated by the Escrow Agent), by wire transfer of immediately available funds, Vox’s Purchase Price in respect of all Subsequent Closings, and (ii) the Company shall not issue or deliver to Vox its Senior Note and
Warrant for the First Closing unless and until such amounts are delivered in accordance with clause (i) above (it being understood that such Senior Note and Warrant to be issued to Vox will be dated as of the date that Vox delivers its
aggregate Purchase Price in respect of all Closings in accordance with clause (i) above). 
 (c) At each Subsequent
Closing, if any, (i) the Company shall issue and deliver to each Purchaser a Senior Note in an original principal amount equal to such Purchaser’s Purchase Price for such Closing, (ii) the Company shall issue and deliver to each
Purchaser such Purchaser’s Warrant for such Closing, (iii) the Escrow Agent shall deliver to the Company the aggregate Purchase Price for all Senior Notes purchased at such Closing other than the Senior Note purchased by Radius at such
Closing and (iv) the Company shall transfer the Purchase Price for the Senior Note purchased by Radius at such Closing from the Special Account to the Company’s general operating account. 

(d) Each Closing shall take place at the office of Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C., One Financial Center, Boston,
Massachusetts, 02111. 
 Section 1.03. Applicability of Charter Provisions. Each of the Company and the Purchasers agree
and acknowledge that (a) the issuance of the Senior Notes and the Warrants is subject to Article Fourth, Section B.3(d)(iii)(D) of the Charter, (b) holders of more than fifty percent (50%) of the outstanding shares of Series C
Convertible Preferred Stock and Series B Convertible Preferred Stock, voting together as a single class on an as-converted basis, have not waived the applicability of Article Fourth, Section B.3(d)(iii)(D) of the Charter with respect to the issuance
of the Senior Notes and the Warrants, (c) one or more holders of the shares of Series A-1 Convertible Preferred Stock or more than 400,000 shares of Series B Convertible Preferred Stock or Series C Convertible Preferred Stock outstanding as of
the date hereof will acquire at least its Pro Rata Share of the Available Additional Shares (as defined in the Charter) of the Senior Notes and the Warrants to be issued pursuant to this Agreement and (d) the Board of Directors of the Company
(the “Board”) (including at least three of the five directors elected by the holders of the Convertible Preferred Stock (as defined in the Charter)) have allocated Senior Notes and Warrants to the holders of at least 75,000 shares
of Series A-1 Convertible Preferred Stock, holders of at least 400,000 shares of Series C Convertible Preferred Stock and holders at least 400,000 shares of Series B Convertible Preferred Stock (other than CII and Radius, as such terms are defined
in the Charter) as set forth on Schedule 1.03. In connection with the foregoing, in the event that any stockholder set forth on Schedule 1.03 hereto, together with its affiliates (as defined in the Charter and including any funds under
common management), fails to purchase all of its Pro Rata Share of the Available Additional Shares of the Senior Notes and the Warrants (each as set forth opposite the name of such Purchaser on Schedule 1.03 hereto), such stockholder shall be
subject to Article Fourth, Section B.3(d)(iii)(D) of the Charter. 
 Section 1.04. Subordination. The Senior Notes shall
be subject to a Second Subordination and Intercreditor Agreement, dated as of May 28, 2010, among the Administrative Agent named therein and the Purchasers and acknowledged by the Company which, among other things,

  
 - 3 -

 
subordinates the Company’s obligations to the Purchasers and the Purchasers’ rights against the Company to the Company’s obligations to the Lenders represented by the
Administrative Agent (the “Senior Indebtedness”). 
 Section 1.05. Priority. (a) Notwithstanding
anything to the contrary contained in the Junior Note Purchase Agreement or the Junior Notes, payment of any and all of the obligations under the Junior Notes shall be subordinate and subject in right and time of payment to the prior payment in full
in cash of all Senior Notes. Each holder of Senior Notes, whether such Senior Notes are issued at the First Closing or any Subsequent Closing, shall be deemed to have acquired such Senior Notes in reliance upon the provisions contained in this
Agreement. Notwithstanding anything to the contrary contained in the Junior Note Purchase Agreement or the Junior Notes, without the consent of the Senior Subordinated Majority, no distribution in cash, securities (other than upon the conversion of
the Junior Notes in accordance with their terms) or other property (whether by set-off or otherwise) shall be made in respect of the Junior Notes until the payment, conversion or a combination thereof, in full of the Senior Notes. 

(b) Notwithstanding the terms of the Junior Note Purchase Agreement or the Junior Notes, the Company hereby agrees that it may not make,
and the holders of the Junior Notes hereby agree that they will not accept any distribution, whether in cash, securities or other property contrary to the foregoing Section 1.05(a), with respect to the Junior Notes. Notwithstanding the
foregoing, the holders of the Junior Notes may, so long as no Default or Event of Default has occurred and is continuing, obtain and retain reasonable out-of-pocket expenses reimbursable by the Company pursuant to Section 5.01 of the Junior
Note Purchase Agreement. 
 (c) If any distribution on account of the Subordinated Debt not permitted to be made by the Company
or accepted by holders of the Junior Notes under this Section 1.05 is made and received by any holder of Junior Notes, such distribution shall not be commingled with any of the assets of such holder of Junior Notes, shall be held in trust by
such holder of Junior Notes for the benefit of the holders of the Senior Notes and shall be promptly paid over to the holders of the Senior Notes for application pro rata to the payment of the Senior Notes then remaining unpaid. 

Section 1.06. Amendment of Junior Notes. The Junior Notes are hereby amended as follows: 

(a) The term “Maturity Date,” as used in the Junior Notes, shall hereafter mean and be defined as the later
of (i) January 8, 2014 and (ii) the 91st
day following the earlier of (y) May 28, 2015 and (z) the date of payment, conversion or a combination thereof, in full of the Senior Notes. 
 (b) The term “equity financing,” as used in the Junior Notes, shall hereafter mean and be defined as any financing in connection with which the Company issues equity securities, including
without limitation, any security convertible or exchangeable into equity securities of the Company, which shall exclude for this purpose (i) any equity securities (and any security convertible or exchangeable into equity securities) of the
Company issued upon conversion of the Junior Notes or the Senior Notes or upon exercise or conversion of the Existing 

  
 - 4 -

 
Warrants or Warrants and (ii) any equity securities issued or issuable to officers, founders, employees or directors of, or consultants to, the Company pursuant to a stock purchase or option
plan or other compensatory stock arrangements existing as of May 28, 2010 or as otherwise approved by the Board of Directors of the Company. 
 (c) The Company and the Purchasers representing the Junior Majority (in such capacity and on behalf of the Junior Noteholders) hereby acknowledge the amendments to the Junior Notes set forth in
subsections (a) and (b) of this Section 1.06 and shall take, and cause to be taken, all such further actions as may be reasonably requested to evidence or effectuate such amendments. 

Section 1.07. Amendment of Junior Note Purchase Agreement. 

(a) The Junior Note Purchase Agreement is hereby amended as follows: 

(i) The first sentence of Section 4.03 of the Junior Note Purchase Agreement and the first sentence of
Section 4.04 of the Junior Note Purchase Agreement each is amended hereby to delete the first four words thereof (“After the date hereof”) and replace them with the words “During the Applicable Period”; 

(ii) Section 4.05 of the Junior Note Purchase Agreement is amended hereby to delete the words “after the date
hereof” and replace them with “during the Applicable Period”; 
 (iii) Article VI of the Junior
Note Purchase Agreement is amended hereby by adding a new Section 6.13 to the end thereof that reads as follows: 

“Section 6.13. Certain Definitions. For purposes of this Agreement: 

(a) “Applicable Period” means any time after the date hereof during which the Senior Eligible Securities are not outstanding;

 (b) “Senior Exchange Securities” shall mean any securities (other than Common Stock) into which any Senior
Subordinated Note is converted or exchanged (excluding any securities of the same class or series that are not issued to the holder thereof upon conversion or exchange of the Senior Subordinated Note); 

(c) “Senior Eligible Securities” shall mean the Senior Subordinated Notes and Senior Exchange Securities; and 

(d) “Senior Subordinated Notes” means those certain Senior Subordinated Convertible Demand Promissory Notes issued by the
Company pursuant to that certain Senior Subordinated Convertible Demand Promissory Note Purchase Agreement, dated May 28, 2010, by and among the Company and certain other parties thereto.” 

  
 - 5 -

 (b) The Company and the Purchasers representing the Junior Majority (in such capacity and on
behalf of the Junior Noteholders) hereby acknowledge the foregoing amendments to the Junior Note Purchase Agreement and shall take, and cause to be taken, all such further actions as may be reasonably requested to evidence or effectuate such
amendments, including the surrender of the Junior Notes for replacement with an identical note reflecting the foregoing amendments. 
 (c) Each holder of Junior Notes will cause to be clearly, conspicuously and prominently inserted on the face of the Junior Notes, as well as any renewals or replacements thereof, the following legend:

 “This instrument and the indebtedness, rights and obligations evidenced hereby and any liens or other
security interests securing such rights and obligations are subordinate in the manner and to the extent set forth in that certain Senior Subordinated Convertible Demand Promissory Note Purchase Agreement dated as of May 28, 2010 (the
“Senior Note Purchase Agreement”), by and among the Company and the Purchasers named therein, to certain indebtedness, rights, and obligations of the Company to such Purchasers as described in the Senior Note Purchase Agreement; and
each holder and transferee of this instrument, by its acceptance hereof, irrevocably agrees to be bound by the provisions of the Senior Note Purchase Agreement.” 
 ARTICLE II 
 REPRESENTATIONS AND WARRANTIES OF THE COMPANY 

The Company represents and warrants to each Purchaser that, except as set forth on a Disclosure Schedule attached hereto as Schedule
2, which exceptions shall be deemed to be representations and warranties as if made hereunder: 
 Section 2.01.
Organization, Corporate Power and Qualification. The Company is a corporation duly incorporated, validly existing and in good standing under the laws of the State of Delaware. The Company has the corporate power and authority to (a) own
and hold its properties and to carry on its business as now conducted and as currently proposed to be conducted, (b) execute, deliver and perform its obligations under this Agreement, the Senior Notes, the Warrants and any other agreements
contemplated hereby or thereby to which the Company is a party (collectively, the “Transaction Documents”) and (c) issue, sell and deliver the Senior Notes and the Warrants and to issue and deliver the shares of common stock,
par value $0.001 per share, of the Company (the “Common Stock”) issuable upon conversion of the Senior Notes or exercise of the Warrants (collectively, the “Conversion Shares”). The Company is duly qualified to
transact business and is in good standing in the State of Connecticut and in each other jurisdiction in which the failure to so qualify would have a material adverse effect on its business, projects, assets or condition (financial or otherwise) (a
“Material Adverse Effect”). 

  
 - 6 -

 Section 2.02. Authorization of Agreements, etc. 

(a) The execution and delivery by the Company of this Agreement and the other Transaction Documents, the performance by the Company of
its obligations hereunder and thereunder, the issuance, sale and delivery of the Senior Notes and the Warrants and the issuance and delivery of the Conversion Shares have been duly authorized by all requisite corporate action and will not
(i) violate any provision of any law applicable to the Company, any order of any court or other agency of government applicable to the Company, (ii) violate the Charter, or the By-laws of the Company, as amended (the
“By-laws”) or (iii) violate any provision of any indenture, agreement or other instrument to which the Company is party or by which the Company is bound, or conflict with, result in a breach of or constitute (with due notice or
lapse of time or both) a default under any such indenture, agreement or other instrument, or result in the creation or imposition of any lien, charge, restriction, claim or encumbrance of any nature whatsoever upon any of the properties or assets of
the Company. 
 (b) The Conversion Shares have been duly reserved for issuance upon conversion of the Senior Notes and upon
exercise of the Warrants, as applicable, and, when so issued, will be duly authorized, validly issued, fully paid and nonassessable shares of Common Stock and will be free and clear of all liens, charges, restrictions, claims and encumbrances
imposed by or through the Company except for restrictions contemplated by this Agreement, the Stockholders Agreement (as defined herein) and the Registration Rights Agreement (as defined herein). Neither the issuance, sale or delivery of the Senior
Notes or the Warrants nor the issuance or delivery of the Conversion Shares is subject to any preemptive right of stockholders of the Company or to any right of first refusal or other right in favor of any person which has not been effectively
waived. 
 Section 2.03. Validity. This Agreement has been duly executed and delivered by the Company and each of this
Agreement and the other Transaction Documents constitute the valid and binding obligations of the Company, enforceable against the Company in accordance with their respective terms. 

Section 2.04. Authorized Capital Stock; Subsidiaries. 
 (a) The authorized capital stock of the Company as of the First Closing consists of 500,000,000 shares of Common Stock and 477,908,245 shares of preferred stock, par value $0.001 per share, of the Company
(the “Preferred Stock”); 7,422,443 shares of Preferred Stock have been designated Series A-1 Convertible Preferred Stock, par value $0.001 per share, 4,695,832 shares of Preferred Stock have been designated as Series A-1(A)
Convertible Preferred Stock, par value $0.001 per share, 3,887,804 shares of Preferred Stock have been designated Series A-L Convertible Preferred Stock, par value $0.001 per share, 92,401,844 shares of Preferred Stock have been designated Series B
Convertible Preferred Stock, par value $0.001 per share, 10,199,547 shares of Preferred Stock have been designated Series B-1 Convertible Preferred Stock, par value $0.001 per share, 77,314,589 shares of Preferred Stock have been designated Series C
Convertible Preferred Stock, par value $0.001 per share and 4,847,310 shares of Preferred Stock have been designated as Series C-1 Convertible Preferred Stock, par value $0.001 per share. Immediately prior to the First Closing, 10,247,529 shares of
Common Stock will be validly issued and outstanding, 7,422,443 shares of Series A-1 Convertible 

  
 - 7 -

 
Preferred Stock will be validly issued and outstanding, 4,695,832 shares of Series A-1(A) Convertible Preferred Stock will be validly issued and outstanding, 3,887,804 shares of Series A-L
Convertible Preferred Stock will be validly issued and outstanding, 92,401,844 shares of Series B Convertible Preferred Stock will be validly issued and outstanding, 10,199,547 shares of Series B-1 Convertible Preferred Stock will be validly issued
and outstanding and 76,345,127 shares of Series C Convertible Preferred Stock will be validly issued and outstanding and 4,847,310 shares of Series C-1 Convertible Preferred Stock will be validly issued and outstanding. As of the First Closing,
there are 42,845,262 shares of Common Stock reserved for issuance to officers, founders, employees or directors of, or consultants to, the Company pursuant to a stock purchase or option plan or other employee stock bonus arrangement (collectively,
the “Plans”). The outstanding shares of Common Stock and Preferred Stock are all duly and validly authorized and issued, fully paid and nonassessable and were issued in accordance with the registration or qualification provisions of
the Securities Act of 1933, as amended (the “Act”), and any relevant state securities laws or pursuant to valid exemptions therefrom. The outstanding shares of Common Stock, Series A-1 Convertible Preferred Stock, Series A-1(A)
Convertible Preferred Stock, Series A-L Convertible Preferred Stock, Series B-1 Convertible Preferred Stock, Series B Convertible Preferred Stock, Series C Convertible Preferred Stock and Series C-1 Convertible Preferred Stock are owned by the
stockholders of the Company in the respective amounts specified in Schedule 2 hereto. Except for the sale of the Senior Notes and the Warrants contemplated by this Agreement, and the outstanding notes, warrants and options set forth on
Schedule 2, no subscription, warrant, option, convertible security or other right (contingent or other) to purchase or otherwise acquire from the Company (or, to the best knowledge of the Company, from any other person or entity) any equity
securities of the Company is outstanding and there is no commitment by the Company to issue shares, subscriptions, warrants, options, convertible securities, or other such rights or to distribute to holders of any of its equity securities, any
evidence of indebtedness or any assets. The Company has no obligation (contingent or other) to purchase, redeem or otherwise acquire any of its equity securities, or any interest therein or to pay any dividend or make any other distribution in
respect thereof. 
 (b) As of the date hereof, the Company does not own or control, directly or indirectly, any equity interest
in any other corporation, partnership, trust, joint venture, association or other entity. 
 Section 2.05. Litigation;
Compliance with Law. There is no: (a) action, suit, claim, proceeding or investigation pending or, to the best knowledge of the Company, threatened against the Company or, to the best knowledge of the Company, any officer of the Company
relating to his or her employment by the Company, at law or in equity, or before or by any federal, state, municipal or other governmental department, commission, board, bureau, agency or instrumentality, domestic or foreign; (b) arbitration
proceeding relating to the Company pending under collective bargaining agreements or otherwise; or (c) governmental inquiry pending or, to the best knowledge of the Company, threatened against the Company (including without limitation any
inquiry as to the qualification of the Company to hold or receive any governmental license or permit), which, in each case, individually or in the aggregate, would reasonably be expected to result in a Material Adverse Effect, and, to the best
knowledge of the Company, there is no basis for any of the foregoing. The Company is not in default with respect to any order, writ, injunction or decree known to or served upon the Company of any court or of any federal, state, municipal or other
governmental department, commission, board, bureau, 

  
 - 8 -

 
agency or instrumentality, domestic or foreign. There is no action or suit by the Company pending or threatened against others. 

Section 2.06. Proprietary Information of Third Parties. To the best knowledge of the Company, no third party has claimed or has
reason to claim that any person employed by or affiliated with the Company has: (a) violated or may be violating any of the terms or conditions of an employment, non-competition or nondisclosure agreement between such employee or affiliate and
such third party; (b) disclosed or may be disclosing or utilized or may be utilizing any trade secret or proprietary information or documentation of such third party; or (c) interfered or may be interfering in the employment relationship
between such third party and any of its present or former employees. No third party has requested information from the Company which suggests that such a claim might be contemplated. To the best knowledge of the Company, no person employed by or
retained as a consultant by the Company has utilized or proposes to utilize any trade secret or any information or documentation proprietary to any third party, and to the best knowledge of the Company, no person employed by or retained as a
consultant by the Company has violated any confidential relationship which such person may have had with any third party, in connection with the development, manufacture or sale by the Company of any product or proposed product or the development or
sale by the Company of any service or proposed service of the Company, and the Company has no reason to believe there will be any such utilization or violation. 
 Section 2.07. Governmental Approvals. Subject to the accuracy of the representations and warranties of the Purchasers set forth in Article III, no registration or filing with, or consent or
approval of or other action by, any federal, state or other governmental agency or instrumentality is or will be necessary for (a) the valid execution, delivery and performance by the Company of this Agreement, (b) the issuance, sale and
delivery of the Senior Notes or the Warrants or (c) upon conversion of the Senior Notes or the exercise of the Warrants, the issuance and delivery of the Conversion Shares (other than filings that may be required pursuant to federal and state
securities laws in connection with the sale of the Senior Notes, the Warrants or the Conversion Shares), the absence of which would not, individually or in the aggregate, reasonably be expected to result in a Material Adverse Effect. 

Section 2.08. Offering of the Senior Notes and Warrants. Neither the Company nor any person authorized or employed by the Company
as agent, broker, dealer or otherwise in connection with the offering or sale of the Senior Notes or the Warrants or any security of the Company similar to the Senior Notes or the Warrants has solicited any offer to buy the Senior Notes or the
Warrants or any such similar security from, or otherwise approached or negotiated with respect thereto with, any person or persons, and neither the Company nor any person acting on its behalf has taken or will take any other action (including,
without limitation, any offer, issuance or sale of any security of the Company under circumstances which might require the integration of such security with the issuance of the Senior Notes or the Warrants under the Act or the rules and regulations
of the Securities and Exchange Commission (the “Commission”) thereunder), in any case so as to subject the offering, issuance or sale of the Senior Notes or the Warrants to the registration provisions of the Act. 

Section 2.09. Brokers. The Company has no contract, arrangement or understanding with any broker, finder or similar agent pursuant
to which the Company or the Purchasers shall 

  
 - 9 -

 
be obligated to make any payment to any such broker, finder or similar agent with respect to the transactions contemplated by this Agreement. 

Section 2.10. Taxes. The Company has filed all tax and information returns which are required to be filed by it and has paid, or
made adequate provision for the payment of, all taxes which have or may become due. The Company does not have any knowledge of any material additional assessments or any basis therefor. The Company has withheld or collected from each payment made to
its employees the amount of all taxes required to be withheld or collected therefrom and has paid over such amounts to the appropriate taxing authorities. 
 Section 2.11. Intellectual Property. 
 (a) The Company owns, free and clear
of all liens, or has the valid right to use all Intellectual Property used by it in its business as currently conducted and as proposed to be conducted. Except as set forth on Schedule 2 hereto, no other person or entity (other than licensors
of software that is generally commercially available, licensors of Intellectual Property under the agreements disclosed pursuant to paragraph (d) below and non-exclusive licensees of the Company’s Intellectual Property in the ordinary
course of the Company’s business) has any rights to any of the Intellectual Property owned or used by the Company, and, to the best knowledge of the Company, other than as set forth on Schedule 2, no other person or entity is infringing,
violating or misappropriating any of the Intellectual Property that the Company owns. For purposes of this Agreement, “Intellectual Property” means all (i) patents, patent applications, patent disclosures and all related
continuation, continuation-in-part, divisional, reissue, reexamination, utility model, certificate of invention and design patents, patent applications, registrations and applications for registrations, (ii) trademarks, service marks, trade
dress, logos, trade names and corporate names and registrations and applications for registration thereof, (iii) copyrights and registrations and applications for registration thereof, (iv) computer software (in both source code and object
code form), data and documentation, (v) trade secrets and confidential business information, whether patentable or unpatentable and whether or not reduced to practice, know-how, manufacturing and production processes and techniques, research
and development information, copyrightable works, financial marketing and business data, pricing and cost information, business and marketing plans and customer and supplier lists and information, and (vi) other proprietary rights relating to
any of the foregoing. 
 (b) To the knowledge of the Company, none of the activities or businesses conducted by the Company
infringes, violates or constitutes a misappropriation of (or in the past infringed, violated or constituted a misappropriation of), and the Company does not have any knowledge, except as set forth on Schedule 2 hereto, that any of the
activities or businesses currently proposed to be conducted by the Company will infringe, violate or constitute a misappropriation of, any Intellectual Property of any other person or entity. The Company has not received any complaint, claim or
notice alleging any such infringement, violation or misappropriation, and to the best knowledge of the Company, there is no basis for any such complaint, claim or notice. 
 (c) Schedule 2 hereto identifies each (i) patent that has been issued or assigned to the Company with respect to any of its Intellectual Property, (ii) pending patent application that the
Company has made with respect to any of its Intellectual Property, (iii) any 

  
 - 10 -

 
copyright or trademark registration or application with respect to the Company’s Intellectual Property, and (iv) license or other agreements pursuant to which the Company has granted
any material rights to any third party with respect to any of its Intellectual Property. 
 (d) Schedule 2 hereto
identifies each agreement with a third party pursuant to which the Company obtains rights to Intellectual Property material to the business of the Company (other than software that is generally commercially available) that is owned by a party other
than the Company. Except as set forth on Schedule 2, other than license fees for software that is generally commercially available, the Company is not obligated to pay any royalties or other compensation to any third party in respect of its
ownership, use or license of any of its Intellectual Property. 
 (e) The Company has taken reasonable precautions (i) to
protect its rights in its Intellectual Property and (ii) to maintain the confidentiality of its trade secrets, know-how and other confidential Intellectual Property, and to the best knowledge of the Company, there have been no acts or omissions
(other than those made based on reasonable, good faith business decisions) by the officers, directors, stockholders and employees of the Company the result of which would be to materially compromise the rights of the Company to apply for or enforce
appropriate legal protection of the Company’s Intellectual Property. 
 (f) Except as set forth on Schedule 2
hereto, all of the Company’s Intellectual Property has been created by employees of the Company within the scope of their employment by the Company or by independent contractors of the Company who have executed agreements expressly assigning
all right, title and interest in such Intellectual Property to the Company. Except as set forth on Schedule 2 hereto, no portion of the Company’s Intellectual Property was jointly developed with any third party. 

Section 2.12. Material Contracts and Obligations. 
 (a) Except for agreements explicitly contemplated hereby and as set forth on Schedule 2, there are no agreements, understandings or proposed transactions between the Company and any of its
officers, directors, affiliates, or any affiliate thereof. 
 (b) Except as set forth on Schedule 2, there are no
agreements, understandings, instruments, contracts, judgments, orders, writs or decrees to which the Company is a party or by which it is bound that may involve (i) provisions restricting or affecting the development, manufacture or
distribution of the Company’s products or services or (ii) indemnification by the Company with respect to infringements of proprietary rights. 
 (c) Except as set forth on Schedule 2, the Company has not (i) declared or paid any dividends or authorized or made any distribution upon or with respect to any class or series of its capital
stock, (ii) incurred any indebtedness for money borrowed or any other liabilities, (iii) made any loans or advances to any person, other than ordinary advances for travel expenses or (iv) sold, exchanged or otherwise disposed of any
of its assets or rights, other than in the ordinary course of business. 

  
 - 11 -

 (d) The Company is not a party to and is not bound by any contract, agreement or instrument,
or subject to any restriction under its Charter or By-laws, that adversely affects its business as now conducted. 
 (e)
Schedule 2 sets forth all agreements or arrangements to which the Company is a party that involve (i) payment from or receipt by the Company of $100,000 or more per annum, or (ii) license to or from the Company of any Intellectual
Property. All such agreements or arrangements are in full force and effect and neither the Company nor, to the best knowledge of the Company, any other party thereto is in breach of such agreements or arrangements. 

Section 2.13. Agreements with Employees. Except as set forth on Schedule 2, each employee, consultant and officer of the
Company has entered into a non-competition, proprietary information and inventions agreement substantially in the form attached hereto as Exhibit C. Each person who is employed by the Company at a level of vice president or higher who has
exercised option(s) to purchase or has otherwise acquired capital stock in the Company since January 1, 2005 has executed a counterpart signature page to the Third Amended and Restated Stockholders Agreement, dated as of June 8, 2006, by
and among the Company and the Stockholders (as defined therein) as amended (the “Stockholders Agreement”) and each person who has received options to purchase capital stock in the Company (except to the extent otherwise determined
by the Board) has executed a stock option agreement containing a right of first refusal in favor of the Company or a counterpart signature page to the Stockholders Agreement. 
 Section 2.14. Permits. The Company has all franchises, permits, licenses, and any similar authority necessary for the conduct of its business as now being conducted by it, the lack of which,
individually or in the aggregate, would reasonably be expected to have a Material Adverse Effect. The Company is not in default under any of such franchises, permits, licenses, or other similar authority. 

Section 2.15. Material Liabilities. Except as reflected in the Financial Statements (as defined in Section 2.18 below), the
Company has no material liability or obligation, absolute or contingent (known or unknown) except (i) obligations and liabilities incurred after the Statement Date (as defined herein) incurred in the Company’s ordinary course of business
that are not material, individually or in the aggregate, to the Company and (ii) obligations under agreements or arrangements made in the Company’s ordinary course of the business but solely to the extent set forth on Schedule 2
pursuant to Section 2.12. 
 Section 2.16. Registration Rights. Except as provided in the Third Amended and Restated
Registration Rights Agreement, dated as of June 8, 2006, by and among the Company and the Purchasers (as defined therein) as amended (the “Registration Rights Agreement”), the Company has not granted or agreed to grant any
registration rights to any person or entity. 
 Section 2.17. Title to Property and Assets. The Company owns its property
and assets free and clear of all mortgages, liens, loans and encumbrances, except such encumbrances and liens that arise in the Company’s ordinary course of business and do not materially impair the Company’s ownership or use of such
property or assets. Each material lease or agreement to 

  
 - 12 -

 
which the Company is a party which is a lease of real or personal property is a valid and existing agreement and the Company is not in default of any material term thereof. With respect to the
property and assets it leases, to the best knowledge of the Company, the Company holds a valid leasehold interest free of any liens, claims or encumbrances. 
 Section 2.18. Financial Statements; Liabilities. (a) The unaudited financial statements of the Company dated as of December 31, 2009 (the “Statement Date”) and the
unaudited financial statements of the Company dated as of March 31, 2010, each attached as Schedule 3 (the “Financial Statements”), (i) comply with the books and records of the Company, which have been maintained in
accordance with good business practice, (ii) have been prepared in conformity with U.S. generally accepted accounting principles and (iii) fairly present the financial position of the Company as of the date thereof and the results of
operations, changes in financial positions or cash flows, as the case may be, for the period presented therein. 
 (b) The
Company has no contingent obligations, liability for taxes or other outstanding obligations which, individually or the aggregate, are material to the Company, except as disclosed in the Financial Statements. 

(c) The Approved Budget has been prepared based upon good faith estimates and assumptions that were reasonable at the time made, at the
time of the delivery of such Approved Budget and as of the date of each making of this representation (it being understood and agreed that such Budget shall not be viewed as fact and that actual results during the periods covered thereby may differ
from such projected results and such differences may be material). 
 Section 2.19. Changes in Condition. Since the
Statement Date, (a) the Company has not incurred any material tax liability, (b) there has been no resignation or termination of employment of any officer or key employee of the Company and the Company does not know of any impending
resignation or termination of employment of any such officer or key employee, (c) there has been no labor dispute involving the Company or any of its respective employees and, to the best knowledge of the Company, none is pending or threatened,
(d) there has been no waiver by the Company of a valuable right or of a debt owing to the Company which, individually or in the aggregate, would reasonably be expected to have a Material Adverse Effect, (e) there has not been any
satisfaction or discharge of any material lien, claim or encumbrance or any payment of any material obligation by the Company except in the Company’s ordinary course of business and (f) there has been no event that would constitute a
Material Adverse Effect. 
 Section 2.20. Insurance. The Company has in effect insurance covering risks associated with
its business in such amounts as are customary in its industry for entities of comparable size. The Company is not aware of any pending or threatened claims against the Company for personal injuries or property damages. The Company currently has
directors’ and officers’ liability insurance with a minimum coverage amount of $3,000,000 per occurrence. 
 Section
2.21. Employee Relations and Compensation Plans. The Company believes its relations with its employees are satisfactory. The Company’s employees are not represented by any labor unions nor, to the best knowledge of the Company, is any
union organization campaign in progress. The Company does not have any present intention to terminate the employment of 

  
 - 13 -

 
any of its employees. Subject to general principles related to wrongful termination of employees, the employment of each officer and employee of the Company is terminable at the will of the
Company. The Company is not a party to or bound by any currently effective employment contracts, deferred compensation agreements, bonus plans, incentive plans, profit sharing plans, retirement plans or agreements, or other employee compensation
agreements. 
 Section 2.22. Transactions with Affiliates. Except for regular salary payments and fringe benefits under
an individual’s compensation package with the Company, no officer, director, or spouse, parent, sibling or child of any such person, or any other employee has any agreement, understanding, proposed transaction or is indebted to the Company, nor
is the Company indebted (or committed to make loans or extend or guarantee credit) to any of them. To the knowledge of the Company, no officer, director or spouse, parent, sibling or child of any such person has any direct or indirect ownership
interest in any firm or corporation with which the Company is affiliated or with which the Company has a business relationship, or any firm or corporation that competes with the Company, except that any such person may own stock in publicly traded
companies that may compete with the Company. To the knowledge of the Company, no spouse, parent, sibling or child of any officer or director of the Company is directly or indirectly interested in any material contract with the Company. 

Section 2.23. Environmental and Safety Laws. The Company, to the best knowledge of the Company, is not in violation of any
applicable statute, law or regulation relating to the environment or occupational health and safety, and, based on the Company’s business as currently conducted, no material expenditures are or will be required in order to comply with any such
existing statute, law or regulation. 
 Section 2.24. Section 83(b) Elections. To the best knowledge of the Company,
all individuals who have purchased shares of the Company’s Common Stock subject at the time of purchase to a substantial risk of forfeiture have timely filed elections under Section 83(b) of the Internal Revenue Code of 1986, as amended,
and any analogous provisions of applicable state tax laws. 
 Section 2.25. Full Disclosure. This Agreement and all other
documents delivered by the Company to the Purchasers or their attorneys or agents in connection with the transactions contemplated therein or herein, when read together and considering the sophistication of the Purchasers and their advisors, do not
contain any untrue statement of a material fact or omit any material fact necessary to make the statements contained therein or herein in view of the circumstances under which they were made not misleading, except that with respect to projections
contained in any such material, the Company represents only that such projections were prepared in good faith and the Company believes that there is a reasonable basis for such projections. The Company does not warrant that it will achieve such
projections or predictions. The Company has provided each Purchaser with all the information that such Purchaser has requested for deciding whether to purchase the Senior Notes and the Warrants. The Company is not aware of any fact which has not
been disclosed to the Purchasers which would have a Material Adverse Effect. 

  
 - 14 -

 ARTICLE III 
 REPRESENTATIONS AND WARRANTIES OF THE PURCHASERS 
 Section 3.01. Each Purchaser,
severally and not jointly, represents and warrants to the Company, with respect only to itself, that: 
 (a) such Purchaser is
an “accredited investor” within the meaning of Rule 501 of Regulation D under the Act; 
 (b) such Purchaser has
sufficient knowledge and experience in investing in companies similar to the Company so as to be able to evaluate the risks and merits of its investment in the Company and is able financially to bear the risks thereof; 

(c) such Purchaser has carefully reviewed the representations concerning the Company contained in this Agreement and has made detailed
inquiry concerning the Company, its business, its financial affairs and its personnel and the officers of the Company have made available to such Purchaser any and all written information which it has requested and have answered to such
Purchaser’s satisfaction all inquiries made by such Purchaser; 
 (d) the Senior Notes and the Warrants being purchased by
such Purchaser (and any Conversion Shares being issued upon conversion thereof) are being acquired for its own account for the purpose of investment and not with a view to or for sale in connection with any distribution thereof; 

(e) such Purchaser understands that: (i) the Senior Notes and the Warrants and the Conversion Shares have not been registered under
the Act by reason of their issuance in a transaction exempt from the registration requirements of the Act pursuant to Section 4(2) thereof or Rule 505 or 506 promulgated under the Act; (ii) the Senior Notes and the Warrants and, upon
conversion thereof, the Conversion Shares must be held indefinitely unless a subsequent disposition thereof is registered under the Act or is exempt from such registration; (iii) the Senior Notes and the Warrants and the Conversion Shares may
bear a legend to such effect; and (iv) the Company will make a notation on its transfer books to such effect; 
 (f) such
Purchaser has no present need for liquidity in connection with its purchase of the Senior Notes and the Warrants; 
 (g) the
purchase of the Senior Notes and the Warrants is consistent with the general investment objectives of such Purchaser, and such Purchaser understands that the purchase of the Senior Notes and the Warrants involves a high degree of risk, and there may
never be an established market for the Company’s capital stock; 
 (h) such Purchaser represents that it is familiar with
Rule 144 under the Act, as presently in effect, and understands the resale limitations imposed thereby and by the Act, including without limitation the Rule 144 condition that current information about the Company be available to the public and such
Purchaser acknowledges that such information is not currently available and the Company has no present intention of making such information available to the public; 

  
 - 15 -

 (i) such Purchaser, if it is not a natural person, is duly organized, validly existing and
in good standing with the laws of its jurisdiction and has all requisite power and authority to enter into this Agreement and each of the other Transaction Documents to which it is a party, and to consummate the transactions contemplated hereby and
thereby; 
 (j) this Agreement and each of the other Transaction Documents to which such Purchaser is a party and all other
documents and instruments executed by such Purchaser pursuant hereto, have each been duly executed and delivered by such Purchaser and each is a legal, valid and binding obligation of such Purchaser enforceable against such Purchaser in accordance
with its terms; and 
 (k) all consents, approvals or authorizations of any person or entity, and all qualifications,
designations, declarations or filings with any governmental entity, on the part of such Purchaser required as a condition precedent to the valid execution and delivery of this Agreement and each of the other Transaction Documents to which such
Purchaser is a party shall have been obtained. 
 ARTICLE IV 

COMPANY’S COVENANTS 
 Section 4.01. Use of Proceeds. The Company shall use the net proceeds from the sale of the Senior Notes and the Warrants hereunder solely for the development and operation of the Company in
accordance with the Approved Budget or as otherwise approved by each of the Board and the Senior Eligible Securities Majority. 

Section 4.02. No Material Adverse Effect. At each Subsequent Closing, the Company shall deliver a certificate, executed by an
officer of the Company, stating that the Company’s representations and warranties set forth in Article II of this Agreement are true and correct in all material respects; provided, however, that the Company may deliver to the
Purchasers updates to the original Schedule 2 not less than five business days prior to the contemplated Subsequent Closing and such updates shall be deemed to modify Schedule 2 for purposes of the certificate delivered pursuant to this
Section 4.02 at such Subsequent Closing. 
 Section 4.03. No Additional Indebtedness. After the date hereof, without
the prior written consent of the Senior Eligible Securities Majority, the Company will not, and will not permit any of its subsidiaries to, (i) directly or indirectly, create, incur, assume, guarantee or otherwise become or remain directly or
indirectly liable with respect to, any indebtedness (other than the indebtedness represented by the Senior Notes, the Junior Notes and the Senior Indebtedness and trade payables incurred in the Company’s ordinary course of business), or
(ii) suffer to exist any additional lien or security interest of any of its assets. 
 Section 4.04. Corporate
Actions. After the date hereof, the Company will not, and will not permit any of its subsidiaries to, take any of the following actions without the prior written consent of the Senior Eligible Securities Majority: 

(a) redeem, purchase or otherwise acquire, or offer to redeem, purchase or otherwise acquire (or pay into or set aside for a sinking fund
for such purpose) any share or shares of the Company’s equity securities; provided, however, that this restriction shall not apply to the 

  
 - 16 -

 
repurchase of shares of Common Stock or any other equity securities of the Company (i) from employees, officers, directors, consultants or other persons performing services for the Company
or any subsidiary pursuant to agreements under which the Company has the option to repurchase such shares at or below cost upon the occurrence of certain events, such as the termination of employment or (ii) pursuant to agreements or
obligations of the Company existing or outstanding on the date hereof; 
 (b) declare or pay any dividend or other distribution
with respect to the Common Stock or any other equity securities of the Company; 
 (c) reclassify any class or series of the
Company’s capital stock; 
 (d) effect any sale, lease, assignment, transfer or other conveyance (other than the grant of a
mortgage or security interest in connection with indebtedness for borrowed money) of all or substantially all the assets of the Company; 
 (e) effect any liquidation, dissolution or winding up of the Company, any recapitalization, consolidation or merger to which the Company is a constituent party, any acquisition of (directly or through
subsidiaries) any entity; 
 (f) effect any transaction or series of related transactions which results in the members of the
Board immediately prior to such transaction or series of transactions holding less than a majority of the seats on the Board immediately after such transaction or series of transactions; 

(g) enter into any partnering or licensing transaction involving material assets of the Company; 

(h) effect any acquisition by the Company of any business or assets, whether by merger or consolidation or by acquisition of assets,
involving the payment by the Company of an amount in excess of $1,000,000; 
 (i) effect any transaction between the Company and
any affiliate of the Company; 
 (j) prepay all or any portion of the Senior Notes; 

(k) move, disburse, transfer or otherwise make any use of the amounts in the Special Account; 

(l) amend or amend and restate the Charter; or 
 (m) except as contemplated by the Stockholders Agreement, change the number of directors on the Board or change the composition of the Board. 

Section 4.05. Issuance of New Securities or Debt. Except for the issuance of the Senior Notes and the Warrants pursuant to this
Agreement, after the date hereof, the Company will not, 

  
 - 17 -

 
and will not permit any of its subsidiaries, to take any of the following actions without the prior written consent of the Senior Eligible Securities Majority: 

(a) (i) create or issue any equity security or any security that is convertible into or exchangeable for any equity security or
(ii) create or issue a security ranking senior to or pari passu with, or convertible into a security ranking senior to or pari passu with, the Senior Notes, including the issuance of subordinated debt; or 

(b) amend, alter, change or modify (or propose to amend, alter, change or modify) the terms and conditions of the Senior Notes or the
Warrants. 
 Section 4.06. Amendment of Stockholders Agreement. Concurrently with the execution of this Agreement, the
Stockholders Agreement shall be amended in the form of such amendment attached hereto as Exhibit D. 
 Section 4.07.
Reserve for Conversion of Shares. The Company shall at all times reserve and keep available out of its authorized but unissued shares of Common Stock, for the purpose of effecting the conversion of the Senior Notes and the exercise of the
Warrants and otherwise complying with the terms of this Agreement, such number of its duly authorized shares of Common Stock as shall be sufficient to effect the conversion of the Senior Notes and exercise of the Warrants from time to time
outstanding or otherwise to comply with the terms of this Agreement. If at any time the number of authorized but unissued shares of Common Stock shall not be sufficient to effect the conversion of the Senior Notes or the exercise of the Warrants or
otherwise to comply with the terms of this Agreement, the Company will forthwith take such corporate action as may be necessary to increase its authorized but unissued shares of Common Stock to such number of shares as shall be sufficient for such
purposes. The Company will obtain any authorization, consent, approval or other action by or make any filing with any court or administrative body that may be required under applicable state securities laws in connection with the issuance of shares
of Common Stock upon conversion of the Senior Notes and the exercise of the Warrants. 
 Section 4.08. Special Account.
The Company shall keep all funds deposited to the Special Account pursuant to this Agreement, as well as all accrued interest thereon, wholly segregated from all other funds held by the Company in any capacity. The Company shall not invest or
reinvest the funds deposited to the Special Account, or any accrued interest thereon, unless directed to do so in writing by the Senior Eligible Securities Majority. Subject to Section 4.04 hereof, the Company shall only move, disburse,
transfer or otherwise make any use of the amounts in the Special Account in accordance with Sections 1.02(b),(c) and 5.03 hereof. 
 ARTICLE V 
 CONDITIONS TO CLOSING; TERMINATION 

Section 5.01. Conditions to Obligations of the Purchasers. The obligations of the Purchasers to purchase Senior Notes and Warrants
on any Closing under this Agreement are subject to the fulfillment, or the waiver in writing by the Senior Eligible Securities Majority, of the conditions set forth in this Section 5.01: 

  
 - 18 -

 (a) Accuracy of Representations and Warranties. The Company shall deliver a
certificate, executed by an officer of the Company, stating that (i) the Company’s representations and warranties set forth in Article II of this Agreement are true and correct in all respects on and as of the date of the First Closing
with the same effect as though such representation and warranty had been made on and as of that date and (ii) the aggregate Purchase Price on such Closing does not exceed by more than $500,000 the budgeted cash needs of the Company for the
90-day period beginning on such Closing in accordance with the Approved Budget (taking into account cash-on-hand on the date of such Closing, but excluding any amounts contained in the Special Account). To the extent necessary to make the
representation and warranty set forth in Section 2.18(c), the Company may deliver with such certificate a revised Approved Budget in form and substance satisfactory to the Senior Eligible Securities Majority, such revised Approved Budget to
constitute the “Approved Budget” upon delivery thereof. 
 (b) Minimum Proceeds to Company. On or prior to the
First Closing, (i) subject to the last sentence of Section 1.02(b), Purchasers shall deliver to the Escrow Agent the aggregate Purchase Price for all Senior Notes and Warrants contemplated to be issued hereunder other than the Senior Notes
and Warrants to be purchased by Radius and (ii) Radius shall deliver to the Special Account the aggregate Purchase Price for all Senior Notes and Warrants contemplated to be issued to Radius hereunder. 

(c) Delivery of the Approved Budget. On or prior to the First Closing, the Company shall deliver to the Purchasers a budget for
the period beginning on or prior to the First Closing and ending on or after the 12-month anniversary thereof, on a monthly basis in form and substance satisfactory to the Senior Eligible Securities Majority. 

(d) Required Consents. On or prior to the First Closing, the Company shall have obtained any and all consents, approvals and
waivers necessary or appropriate for consummation of the transactions contemplated by this Agreement, including, without limitation, (i) any consents or approvals required to be granted by the Board, (ii) any consents or approvals required
to be granted by holders of the Preferred Stock, (iii) any consents or approvals required to be granted by holders of the Junior Notes and (iv) waivers of any and all participation rights or anti-dilution protection provisions held by or
applicable to holders of the Preferred Stock, the Junior Notes or the Existing Warrants, each in a form satisfactory to the Senior Eligible Securities Majority. 
 Section 5.02. Termination. This Agreement shall automatically terminate and the transactions contemplated hereby shall be abandoned without any further action by any party hereto if the First
Closing shall not have occurred on or prior to June 30, 2010. In the event of the termination of this Agreement, this Agreement will forthwith become void, and there will be no liability on the part of the Company or any Purchaser and all
rights and obligations of any party hereto will cease, except that nothing herein will relieve any party from liability for any breach, prior to termination of this Agreement in accordance with its terms, of any representation, warranty, covenant or
agreement contained in this Agreement. 
 Section 5.03. Cancellation of Remaining Subsequent Closings. At any time, upon
the request or approval of the Senior Eligible Securities Majority, any Subsequent Closings that have not previously occurred shall automatically be cancelled, the obligations of the parties in respect

  
 - 19 -

 
thereof shall be terminated and be of no further force or effect and the Company and (a) the Purchasers shall cause all funds remaining with the Escrow Agent in respect of such Subsequent
Closings to be returned to the Purchasers pro rata in accordance with each Purchaser’s respective percentage of funds placed with the Escrow Agent in respect of such Subsequent Closings and (b) the Company shall cause all funds
remaining with the Company in the Special Account in respect of such Subsequent Closings to be returned to Radius. In the event of the cancellation of any Subsequent Closing, there will be no liability on the part of the Company or any Purchaser
with respect to such Subsequent Closing and all rights and obligations of any party with respect thereto will cease. 
 ARTICLE
VI 
 MISCELLANEOUS 
 Section 6.01. Expenses. The Company will pay its own expenses in connection with the transactions contemplated hereby, and the Company will reimburse the Purchasers for their reasonable
out-of-pocket expenses (including, without limitation, reasonable fees and expenses of one or more law firms acting as special legal counsel for the Purchasers and other outside advisors and consultants utilized by the Purchasers) in connection with
the transactions contemplated by this Agreement, including any amendments to the Agreement and enforcement of the Purchasers’ rights hereunder. 
 Section 6.02. Survival of Representations, Warranties and Covenants. All covenants, agreements, representations and warranties made herein or in any agreement, certificate or instrument delivered
to the Purchasers pursuant to or in connection with this Agreement shall survive the execution and delivery of this Agreement, the issuance, sale and delivery of the Senior Notes and the Warrants and the issuance and delivery of the Conversion
Shares. 
 Section 6.03. Brokerage. The Company will indemnify and hold the Purchasers harmless against and in respect of
any claim for brokerage or other commissions relative to this Agreement or to the transactions contemplated hereby, based in any way on agreements, arrangements or understandings made or claimed to have been made by the Company or any of its
subsidiaries with any third party. 
 Section 6.04. Parties in Interest. All representations, covenants and agreements
contained in this Agreement by or on behalf of any of the parties hereto shall bind and inure to the benefit of the respective successors and assigns of the parties hereto whether so expressed or not. 

Section 6.05. Notices. All notices, requests, consents and other communications hereunder shall be in writing and shall be:
(a) delivered in person; (b) mailed by certified or registered mail, return receipt requested; (c) sent by a recognized overnight courier service; or (d) sent by e-mail, facsimile or other means of electronic communication, for
which evidence of delivery is automatically generated (provided that if notice is provided pursuant to this clause (d), such communication is followed promptly by a communication in the form provided under clauses (a), (b) or (c)), addressed as
follows: 
  

	 	(a)	if to the Company, at 

  
 - 20 -

 Rib-X Pharmaceuticals, Inc. 

300 George Street, Suite 301 
 New Haven, CT 06511 
 Attention: Chief Executive Officer 

Telephone: (203) 624-5606 
 Facsimile: (203) 624-5627 
 with a copy to: 

Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C. 
 One Financial Center 
 Boston, MA 02111 

Attention: Jonathan L. Kravetz, Esq. 
 Telephone: (617) 542-6000 
 Facsimile: (617) 542-2241 

 

	 	(b)	if to a Purchaser, at the address of such Purchaser set forth on Schedule 1.01 hereto, 

with a copy to: 
 Willkie Farr & Gallagher LLP 
 787 Seventh Avenue 

New York, NY 10019 
 Attention: Steven J. Gartner, Esq. 
 Telephone: (212) 728-8222

 Facsimile: (212) 728-9222 
 or, in any such case, at such other address as shall have been furnished in writing by the addressee to the others. Notices shall be effective: (i) upon delivery, if delivered in person;
(ii) three (3) days after deposit in the U. S. mails, if mailed; (iii) on the day following deposit with the courier service, if sent by overnight courier; and (iv) upon transmission, if sent by e-mail, facsimile or other means
of electronic communication. 
 Section 6.06. Governing Law. This Agreement shall be governed by and construed in
accordance with the laws of the State of New York, without application of the conflicts of law principles thereof. 
 Section
6.07. Entire Agreement. This Agreement and the other Transaction Documents constitute the sole and entire agreement of the parties with respect to the subject matter hereof. 

Section 6.08. Counterparts. This Agreement may be executed in counterparts, each of which shall be deemed an original, but all of
which together shall constitute one and the same instrument. Signatures delivered by facsimile transmission shall be deemed to be originals notwithstanding the failure subsequently to deliver a hard copy thereof. 

Section 6.09. Amendments and Waivers. This Agreement may be amended or modified, and provisions hereof may be waived, only with
the written consent of the Company and the 

  
 - 21 -

 
Senior Eligible Securities Majority; provided, however, that (a) the “Aggregate Purchase Price” specified for a Purchaser on Schedule 1.01 hereto may not
be increased, and (b) the percentage of Senior Notes to be purchased at any Closing by a Purchaser may not be amended, in each case, without the written consent of such Purchaser; provided, further, that any amendment modification
or waiver of a provision of this Agreement that by its terms treats a particular Purchaser in a materially different and adverse manner relative to the other Purchasers shall not be binding as to such Purchaser unless such Purchaser consents in
writing to the amendment, modification or waiver. 
 Section 6.10. Severability. If any provision of this Agreement shall
be declared void or unenforceable by any judicial or administrative authority, the validity of any other provision and of the entire Agreement shall not be affected thereby. 
 Section 6.11. Titles and Subtitles. The titles and subtitles used in this Agreement are for convenience only and are not to be considered in construing or interpreting any term or provision of this
Agreement. 
 Section 6.12. No Waiver; Cumulative Remedies. No failure or delay on the part of any party to this
Agreement in exercising any right, power or remedy hereunder shall operate as a waiver thereof; nor shall any single or partial exercise of any such right, power or remedy preclude any other or further exercise thereof or the exercise of any other
right, power or remedy hereunder. The remedies herein provided are cumulative and not exclusive of any remedies provided by law. 
 Section 6.13. Certain Definitions. For purposes of this Agreement: 
 (a)
“Junior Majority” means the Majority Noteholders as such term is defined in the Junior Note Purchase Agreement; 
 (b) “Senior Eligible Securities Majority” means, at any time that any Senior Notes are outstanding, the Senior Subordinated Majority and, at any time that any Senior Exchange Securities
are outstanding and no Senior Notes are outstanding, the holders of a majority of the Senior Exchange Securities (determined on an as converted basis); 
 (c) “Senior Exchange Securities” shall mean any securities (other than Common Stock) into which any Senior Note is converted or exchanged (excluding any securities of the same class or
series that are not issued to the holder thereof upon conversion or exchange of the Senior Note); 
 (d) “Senior
Subordinated Majority” means (a) prior to the First Closing, Purchasers obligated to acquire Senior Notes representing at least a majority of the aggregate principal amounts of all of the Senior Notes to be issued and sold hereunder,
and (b) from and after the First Closing, Purchasers holding Senior Notes representing at least a majority of the aggregate principal amounts of the then outstanding Senior Notes. 

[REMAINDER OF PAGE INTENTIONALLY LEFT BLANK] 

  
 - 22 -

 IN WITNESS WHEREOF, the Company and the Purchasers have executed this Agreement as of the
day and year first above written. 
  

					
	THE COMPANY:
	
	RIB-X PHARMACEUTICALS, INC.
		
	By:	 	 /s/ Mark Leuchtenberger

		 	Name:	 	Mark Leuchtenberger
		 	Title:	 	President and Chief Executive Officer

 [Signature Page to Senior Subordinated Convertible Demand Note Purchase Agreement] 

 
					
	THE PURCHASERS:
	WP VIII FINANCE, L.P.
	By:	 	WPVIII GP, L.P., its General Partner
	By:	 	Warburg Pincus Private Equity VIII, L.P.,
		 	its General Partner
	By:	 	Warburg Pincus Partners, LLC, its General Partner
	By:	 	Warburg Pincus & Co., its Managing Member
		
	By:	 	 /s/ Jonathan Leff

		 	Name:	 	Jonathan Leff
		 	Title:	 	Partner
	
	EUCLIDSR BIOTECHNOLOGY PARTNERS, L.P.
	By:	 	EuclidSR Associates, L.P.
	Its:	 	General Partner
		
	By:	 	 /s/ Raymond J. Whitaker

		 	Name:	 	Raymond J. Whitaker
		 	Title:	 	General Partner
	
	EUCLIDSR PARTNERS, L.P.
	By:	 	EuclidSR Associates, L.P.
	Its:	 	General Partner
		
	By:	 	 /s/ Raymond J. Whitaker

		 	Name:	 	Raymond J. Whitaker
		 	Title:	 	General Partner
	
	OXFORD BIOSCIENCE PARTNERS IV L.P.
	By:	 	OBP Management IV L.P.
		
	By:	 	 /s/ Jonathan Fleming

		 	Name:	 	Jonathan Fleming
		 	Title:	 	Managing General Partner
	
	RADIUS VENTURE PARTNERS II L.P.
	By:	 	Radius Venture Partners II, LLC
		 	its General Partner
		
	By:	 	 /s/ Jordan Davis

		 	Name:	 	Jordan Davis
		 	Title:	 	Managing Partner

 [Signature Page to Senior Subordinated Convertible Demand Note Purchase Agreement] 

 
					
	MRNA FUND II L.P.
	By:	 	OBP Management IV L.P.
		
	By:	 	  

		 	Name:	 	Jonathan Fleming
		 	Title:	 	Managing General Partner
	
	ABS VENTURES VII, L.P.
	By:	 	Calvert Capital Caymans I L.L.C.
		
	By:	 	  

		 	Name:	 	Bruns Grayson
		 	Title:	 	Senior
	
	AXIOM VENTURE PARTNERS III, LP
		
	By:	 	 /s/ Alan Mendelson

		 	Name:	 	Alan Mendelson
		 	Title:	 	General Partner
	
	MEDIMMUNE VENTURES, INC.
		
	By:	 	  

		 	Name:	 	Peter Greenleaf
		 	Title:	 	

  

					
	  
	 		 	  

	Thomas Steitz	 		 	Joan Steitz

 [Signature Page to Senior Subordinated Convertible Demand Note Purchase Agreement] 

 
					
	CHP II L.P.
	By:	 	CHP II Management, LLC
		 	its General Partner
		
	By:	 	 /s/ John J. Park

		 	Name:	 	John J. Park
		 	Title:	 	Managing Member

 [Signature Page to Senior Subordinated Convertible Demand Note Purchase Agreement] 

 
					
	MRNA FUND II L.P.
	By:	 	OBP Management IV L.P.
		
	By:	 	 /s/ Jonathan Fleming

		 	Name:	 	Jonathan Fleming
		 	Title:	 	Managing General Partner

 [Signature Page to Senior Subordinated Convertible Demand Note Purchase Agreement] 

 
					
	S.R. ONE, LIMITED
		
	By:	 	 /s/ John Keller

		 	Name:	 	John Keller
		 	Title:	 	Vice President
	
	VOX EQUITY PARTNERS, L.P.
		
	By:	 	 /s/ Matthew Kelley

		 	Name:	 	M. Kelley
		 	Title:	 	MGP
	
	 /s/ C. Boyd Clarke

	C. Boyd Clarke
	
	 /s/ Elaine Jones

	Elaine Jones

 [Signature Page to Senior Subordinated Convertible Demand Note Purchase Agreement] 

 
					
	VOX EQUITY PARTNERS II, L.P.
		
	By:	 	 /s/ Sharon Alvarez

		 	Name:	 	Sharon Alvarez
		 	Title:	 	Director
		
	By:	 	Vox II General Partner LLC, its
		 	General Partner
		
	By	 	Omega Fund III G.P. LP.

 [Signature Page to Senior Subordinated Convertible Demand Note Purchase Agreement] 

 
					
	 /s/ Thomas Steitz
	 		 	 /s/ Joan Steitz

	Thomas Steitz	 		 	Joan Steitz

 [Signature Page to Senior Subordinated Convertible Demand Note Purchase Agreement] 

 
	
	 /s/ Barbara Dalton

	Barbara Dalton

 [Signature Page to Senior Subordinated Convertible Demand Note Purchase Agreement] 

 
	
	 /s/ Susan Froshauer

	Susan Froshauer

 [Signature Page to Senior Subordinated Convertible Demand Note Purchase Agreement]

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00196-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00196-of-00352.parquet"}]]