Document:

exv10w14f

 

Exhibit 10.14F

Fifth Addendum to Consulting Agreement

Dated February 1, 2000

     This Fifth Addendum is made by and between Avalon Pharmaceuticals, Inc. (formerly Therapeutic
Genomics, Inc.) a Delaware corporation, located at 20358 Seneca Meadows Parkway, Germantown, MD
20876 (“AVALON”), and Bradley G. Lorimier, an individual with an address at 7807 Fox Gate Court,
Bethesda, MD 20817 (“CONSULTANT”).

     In exchange for Consultant’s commitment to provide additional support to AVALON’S business
development efforts, AVALON agrees to extend CONSULTANT’S contract term until December 31, 2007, or
until terminated as set forth in section 6 of the February 1, 2000 Agreement.

     CONSULTANT’S compensation will be $10,000 per month.

     CONSULTANT acknowledges continuing to be bound by the terms and conditions of the agreement
entitled “Confidentiality, Assignment of Inventions and Non-Competition Agreement” (Exhibit B)
dated February 1, 2000.

     CONSULTANT acknowledges that all other terms and conditions of the February 1, 2000 agreement
are in full force and effect during the term of this extension.

READ, AGREED AND ACCEPTED:

Signed for and on behalf of

	 	 	 	 	 	 	 	 	 	 	 
	AVALON PHARMACEUTICALS, INC.	 	 	 	BRADLEY G. LORIMIER	 	 
	 
	 	 	 	 	 	 	 	 	 	 
	By:

	 	/s/ Kenneth C. Carter, Ph.D.
	 	 	 	By:
	 	/s/ Bradley G. Lorimier	 	 
	 

	 	 
	 	 	 	 	 	 	 	 
	Name:

	 	Kenneth C. Carter, Ph.D
	 	 	 	Date:
	 	January 5, 2007	 	 
	Title:

	 	CEO & President	 	 	 	 	 	 	 	 
	Date:

	 	January 5, 2007exv10w14g

 

Exhibit 10.14G

Amendment No. 6 to

CONSULTING AGREEMENT

By and Between

Avalon Pharmaceuticals, Inc. and Bradley G. Lorimier

     The parties hereby agree, effective August 1, 2007 (“Effective Date”), to amend the Consulting
Agreement by and between Avalon Pharmaceuticals, Inc. (“Company” or “the Company”) and Bradley G.
Lorimier (“Consultant” or “the Consultant”) as set forth herein.

     1) For purposes of this “Amendment No. 6”, “Agreement” shall refer to the Consulting
Agreement between the parties dated February 1, 2000 (including, without limitation, all Exhibits
and Addendums to that Consulting Agreement).

     2) Company and Consultant agree to amend and extend the term of the Agreement to have a
Renewal Term expiring December 31, 2008, at which time the Agreement shall automatically renew each
January 1 thereafter for additional terms of twelve (12) months each (“Renewal Term”) unless either
party gives to the other party at least thirty (30) days written notice of termination.

     3) As of the Effective Date, Consultant’s compensation will be $4,583.33 per month (or
$55,000 per year).

     4) All provisions of the Agreement shall continue in full force and effect and shall apply
with full force and effect to this Amendment No. 6, except where expressly superseded herein. The
Agreement is hereby incorporated by reference into this Amendment No. 6 as if fully set forth
herein.

     In witness whereof, the parties have executed this Amendment No. 6 as of the Effective Date
set forth above.

Agreed:

	 	 	 	 	 	 	 	 	 
	COMPANY	 	 	 	CONSULTANT	 	 
	 
	 	 	 	 	 	 	 	 
	By:

	 	/s/ Kenneth C. Carter, Ph.D.
	 	 	 	/s/ Bradley G. Lorimier	 	 
	 

	 	 
	 	 	 	 	 	 
	 

	 	Kenneth C. Carter, Ph.D.
	 	 	 	Bradley G. Lorimier	 	 
	 

	 	President & CEOexv10w48e

 

Exhibit 10.48 E

THIRD MODIFICATION AGREEMENT

     THIS THIRD MODIFICATION AGREEMENT (“AGREEMENT”) is made to be effective as of the
14 day of December, 2006, by and between MANUFACTURERS AND TRADERS TRUST COMPANY (“BANK”);
MARYLAND INDUSTRIAL DEVELOPMENT FINANCING AUTHORITY (“ISSUER”); and AVALON PHARMACEUTICALS, INC.
(“BORROWER”).

RECITALS

     The ISSUER has issued and sold certain bonds (“BONDS”) in the aggregate amount of Twelve
Million Dollars ($12,000,000) and has lent the proceeds thereof to the BORROWER in accordance with
the terms of a Loan Agreement dated April 1, 2003 (“LOAN AGREEMENT”). In order to enhance the
marketability of the BONDS, the BORROWER has entered into a Letter Of Credit Agreement dated April
1, 2003 (“LC AGREEMENT”) pursuant to which the BANK issued to the Trustee named therein for the
holders of the BONDS the BANK’S irrevocable letter of credit (“LETTER OF CREDIT”). As a condition
to its issuance of the LETTER OF CREDIT, the BANK required the ISSUER to insure a portion of the
BORROWER’S obligations under the LC AGREEMENT in accordance with the terms of the Issuer’s
Insurance Agreement dated April 1, 2003 (“INSURANCE AGREEMENT”).

     As a condition precedent to the issuance of the BONDS and the issuance of the LETTER OF
CREDIT, the BORROWER was required in accordance with the terms of a Collateral Pledge And Security
Agreement And Control Agreement dated April 1, 2003, as amended by an Amendment thereto dated July
6, 2004 (“COLLATERAL/CONTROL AGREEMENT”) to post and maintain cash collateral and/or securities in
Account Number 80366 (“COLLATERAL ACCOUNT”) held by and maintained with Allfirst Trust Company
National Association (“SECURITIES INTERMEDIARY”), which COLLATERAL ACCOUNT and the cash, securities
and properties therein were pledged in accordance with the terms of the COLLATERAL/CONTROL
AGREEMENT to secure to the BANK the BORROWER’S “LETTER OF CREDIT OBLIGATIONS,” as such term is
defined in the LOAN AGREEMENT. The SECURITIES INTERMEDIARY was subsequently merged with the BANK,
with the BANK being the surviving entity. The BANK, the ISSUER, and the BORROWER entered into an
Amended And Restated Modification And Consent Agreement dated to be effective as of February 15,
2005 (“FIRST MODIFICATION”), and a Second Modification Agreement dated to be effective as of August
9, 2005 (“SECOND MODIFICATION”). Hereafter, the BONDS, the LOAN AGREEMENT, the LC AGREEMENT, the
INSURANCE AGREEMENT, the COLLATERAL/CONTROL AGREEMENT, the FIRST MODIFICATION, the SECOND
MODIFICATION, and all other documents and agreements which evidence, secure, relate or pertain to
the BONDS and the loan of the proceeds of the BONDS by the ISSUER to the BORROWER, or the issuance
of the LETTER OF CREDIT by the Bank or the BORROWER’S obligations to the Bank in connection
therewith are collectively referred to as the “DOCUMENTS.”

     The BORROWER has requested that the ISSUER and the BANK agree to modify the amount of the
annual fee for the LETTER OF CREDIT. The BANK and the ISSUER have entered into this AGREEMENT to
accomplish such modification.

     NOW, THEREFORE, in consideration of the premises, and other good and valuable consideration,
the receipt and adequacy of which are hereby acknowledged, the parties hereby agree as follows:

 

 

AGREEMENT

     Section 1. Acknowledgment Of Obligations. The BORROWER acknowledges that: (a) each of
the DOCUMENTS to which the BORROWER is a signatory constitutes the valid and binding obligation of
the BORROWER; (b) the DOCUMENTS are enforceable against the BORROWER in accordance with all stated
terms; and (c) the BORROWER has no defenses, claims of offset, or counterclaims against the
enforcement of the DOCUMENTS in accordance with all stated terms.

     Section 2. Modification of LC Agreement. The BANK and the BORROWER agree that
effective as of April 7, 2006, the “Letter of Credit Fee” (as defined in Section 4.1(a) of the LC
AGREEMENT) (“LETTER OF CREDIT FEE”) shall be reduced from 1.90% as referenced in Section 4.1(a) of
the LC AGREEMENT to 1.5%.

     Section 3. Payment of 2006 Annual Letter of Credit Negotiation Fee And 2006 Letter of
Credit Fee. The Borrower agrees to pay to the BANK upon the execution and delivery of this
AGREEMENT: (a) One Thousand Two Hundred Dollars ($1,200.00) as payment of the 2006 annual
negotiation fee for the LETTER OF CREDIT; and (b) One Hundred Twenty-Nine Thousand Eight Hundred
Fifty Dollars ($129,850.00) as payment of the 2006 LETTER OF CREDIT FEE for the period of April 7,
2006 through April 6, 2007.

     Section 4. Acknowledgments Of Issuer. The ISSUER acknowledges that the INSURANCE
AGREEMENT is in full force and effect and to the best of the ISSUER’S knowledge, the BORROWER and
the BANK are each in compliance with all of their respective obligations thereunder.

     Section 5. Expenses. The BORROWER agrees to pay to the BANK upon the execution and
delivery of this AGREEMENT by the BORROWER the sum of One Thousand Eight Hundred Seventy-Five
Dollars ($1,875.00) as reimbursement for the attorneys’ fees and expenses incurred by the BANK in
connection with this AGREEMENT.

     Section 6. No Novation. It is the intent of the BORROWER, the ISSUER, and the BANK
that nothing contained in this AGREEMENT shall be deemed to effect or accomplish or otherwise
constitute a novation of any of the DOCUMENTS or of any of the obligations owed by the BORROWER in
accordance with any of the DOCUMENTS.

     Section 7. Enforceability. This AGREEMENT shall inure to the benefit of and be
enforceable against the parties hereto and their respective successors and assigns.

     Section 8. Choice Of Law; Consent To Jurisdiction; Agreement As To Venue. This
AGREEMENT shall be construed, performed and enforced and its validity and enforceability determined
in accordance with the laws of the State of Maryland (excluding, however, conflict of laws
principles). The BORROWER consents to the jurisdiction of the courts of the State of Maryland and
the jurisdiction of the United States District Court for the District of Maryland, if a basis for
federal jurisdiction exists. The BORROWER waives any right to object to the maintenance of a suit
in any of the state or federal courts of the State of Maryland on the basis of improper venue or
inconvenience of forum.

     Section 9. Waiver Of Jury Trial. Each of the parties agrees that any suit, action, or
proceeding, whether claim or counterclaim, brought or instituted by any of the parties, or any
successor or assign of any of the parties , on or with respect to this AGREEMENT or any of the
DOCUMENTS or which in any way relates, directly or indirectly, to the obligations of the BORROWER
under the DOCUMENTS or this AGREEMENT or the dealings of the parties with respect thereto, shall be
tried by a court and not by a jury. THE PARTIES

2

 

HEREBY EXPRESSLY WAIVE ANY RIGHT TO A TRIAL BY JURY IN ANY SUCH SUIT, ACTION, OR PROCEEDING.

     Section 10. RELEASE. IN ORDER TO INDUCE THE BANK AND THE ISSUER TO ENTER INTO THIS
AGREEMENT, THE BORROWER FOREVER RELEASES AND DISCHARGES THE BANK AND THE ISSUER AND THE OFFICERS,
DIRECTORS, EMPLOYEES, ATTORNEYS, AGENTS, SUCCESSORS, AND ASSIGNS OF THE BANK AND THE ISSUER
(COLLECTIVELY, THE “RELEASED PARTIES”) FROM ANY AND ALL CLAIMS, CAUSES OF ACTION, SUITS AND DAMAGES
(INCLUDING CLAIMS FOR ATTORNEYS’ FEES AND COSTS) WHICH THE BORROWER EVER HAD OR MAY NOW HAVE
AGAINST ANY OF THE RELEASED PARTIES, WHETHER KNOWN OR UNKNOWN, INCLUDING BUT NOT LIMITED TO ANY AND
ALL CLAIMS BASED UPON OR RELYING ON ANY ALLEGATIONS OR ASSERTIONS OF DURESS, ILLEGALITY,
UNCONSCIONABILITY, BAD FAITH, BREACH OF CONTRACT, REGULATORY VIOLATIONS, NEGLIGENCE, MISCONDUCT, OR
ANY OTHER TORT, CONTRACT OR REGULATORY CLAIM OF ANY KIND OR NATURE. THIS RELEASE IS INTENDED TO BE
FINAL AND IRREVOCABLE AND IS NOT SUBJECT TO THE SATISFACTION OF ANY CONDITIONS OF ANY KIND.

     IN WITNESS WHEREOF, the parties have executed this AGREEMENT with the specific intention of
creating a document under seal to be effective as of the date first above written. This AGREEMENT
may be executed and delivered in counterparts. Signatures to this AGREEMENT may be delivered
electronically.

	 	 	 	 	 	 
	WITNESS/ATTEST: 	 	AVALON PHARMACEUTICALS, INC.

 	 
	 	 	By:  	

 	(SEAL) 
	 	 	 	Name:  	Kenneth C. Carter                                                 	 
	 	 	 	Title:  	President & CEO 	 
	 

[SIGNATURES CONTINUED ON THE FOLLOWING PAGE]

3

 

Signature Page to Third Modification Agreement — Continued:

	 	 	 	 	 	 
	WITNESS/ATTEST: 	 	MARYLAND INDUSTRIAL DEVELOPMENT

                FINANCING AUTHORITY

 	 
	 	 	By:  	 	(SEAL) 
	 	 	 	Name:  	D. Gregory Cole 	 
	 	 	 	Title:  	Executive Director 	 
	 

[SIGNATURES CONTINUED ON THE FOLLOWING PAGE]

4

 

Signature Page to Third Modification Agreement — Continued:

	 	 	 	 	 	 
	 	 	MANUFACTURERS AND TRADERS TRUST

COMPANY

 	 
	
 	 	By:  	
 	(SEAL) 
	 	 	 	Name:  	Humberta M. Salomon 	 
	 	 	 	Title:  	Assistant Vice President 	 
	 	 

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