Document:

Exhibit 4.3

 

GRUPO FINANCIERO SANTANDER MÉXICO,
S.A.B. DE C.V.

as Company

 

 

 

TO

 

 

 

THE BANK OF NEW YORK MELLON

as Trustee, Transfer Agent, Contingent Convertible Security Registrar and Paying Agent

 

 

 

INDENTURE

 

 

 

CONTINGENT CONVERTIBLE SECURITIES

 

 

 

    	 

     

    

GRUPO FINANCIERO SANTANDER MÉXICO,
S.A.B. DE C.V.

 

Reconciliation and tie between Trust Indenture
Act of 1939, as amended by the Trust Indenture Reform Act of 1990, and Contingent Convertible Securities Indenture, dated as of                            ,
2016.

 

	
        Trust Indenture

Act Section
	
        Contingent
Convertible Securities Indenture Section

	§310	(a)(1)	6.09
	 	(a)(2)	‎6.09
	 	(a)(3)	6.14
	 	(a)(4)	6.12
	 	(b)	‎6.08, 6.09
	§311	(a)	‎6.13
	 	(b)	‎6.13
	 	(b)(2)	‎7.03(a), ‎7.03(c)
	§312	(a)	‎7.01, ‎7.02(a)
	 	(b)	‎7.02(b)
	 	(c)	‎7.02(c)
	§313	(a)	‎7.03(a), 7.03(b)
	 	(b)	‎7.03(a)
	 	(c)	‎1.06, ‎7.03(a), 7.03(b)
	 	(d)	‎7.03(c)
	§314	(a)	‎7.04, ‎9.06
	 	(b)	Not Applicable
	 	(c)(1)	‎1.02
	 	(c)(2)	‎1.02
	 	(c)(3)	Not Applicable
	 	(d)	Not Applicable
	 	(e)	‎1.02
	 	(f)	Not Applicable
	§315	(a)	‎6.01
	 	(b)	‎6.04, ‎7.03(a)
	 	(c)	Not Applicable
	 	(d)	‎6.01
	 	(d)(1)	‎6.01
	 	(d)(2)	‎6.01
	 	(d)(3)	‎6.01
	 	(e)	5.12
	§316	(a)(1)(A)	‎5.11
	 	(a)(1)(B)	Not Applicable
	 	(a)(2)	Not Applicable
	 	(a)(last sentence)	‎1.01
	 	(b)	‎5.07
	 	(c)	‎1.04
	§317	(a)(1)	Not Applicable
	 	(a)(2)	‎5.03
	 	(b)	‎9.03
	§318	(a)	‎1.07

 

NOTE: This reconciliation and tie shall not, for any purpose,
be deemed to be a part of the Contingent Convertible Securities Indenture.

 

    	 

     

    

TABLE OF CONTENTS

 

		Page
	 	 
	Article 1
	Definitions and Other Provisions of General Application
	 
	Section 1.01. Definitions	1
	Section 1.02. Compliance Certificates and Opinions	6
	Section 1.03. Form of Documents Delivered to the Trustee	6
	Section 1.04. Acts of Holders	7
	Section 1.05. Notices, Etc	7
	Section 1.06. Notice to Holders; Waiver	8
	Section 1.07. Conflict with Trust Indenture Act	8
	Section 1.08. Effect of Headings and Table of Contents	8
	Section 1.09. Successors and Assigns	8
	Section 1.10. Separability Clause	8
	Section 1.11. Benefits of Contingent Convertible Securities Indenture	8
	Section 1.12. Currency Indemnity	9
	Section 1.13. Governing Law	9
	Section 1.14. Submission to Jurisdiction; Waiver of Immunities	9
	Section 1.15. Saturdays, Sundays and Legal Holidays	9
	Section 1.16. Appointment of Agent for Service	10
	Section 1.17. Calculation Agent	10
	Section 1.18. Waiver of Jury Trial	10
	 	 
	Article 2
	Contingent Convertible Security Forms
	 
	Section 2.01. Forms Generally	10
	Section 2.02. Form of Trustee’s Certificate of Authentication	10
	 	 
	Article 3
	The Contingent Convertible Securities
	 
	Section 3.01. Amount Unlimited, Issuable in Series	11
	Section 3.02. Denominations	13
	Section 3.03. Execution, Authentication, Delivery and Dating	13
	Section 3.04. Temporary Contingent Convertible Securities	13
	Section 3.05. Registration, Registration of Transfer and Exchange	14
	Section 3.06. Mutilated, Destroyed, Lost and Stolen Contingent Convertible Securities	16
	Section 3.07. Payment; Interest Rights Preserved	16
	Section 3.08. Persons Deemed Owners	17
	Section 3.09. Cancellation	17
	Section 3.10. Computation of Interest	17
	Section 3.11. CUSIP Numbers	17
	Section 3.12. Additional Contingent Convertible Securities	17
	Section 3.13. Correction of Minor Defects in or Amendment of Contingent Convertible Securities	17
	Section 3.14. General Rules Applicable to Mexican Banks and Their Application to the Bank	17
	Section 3.15. Restrictions Applicable to the Bank and to Other Mexican Financial Institutions	19
	 	 
	Article 4
	Satisfaction and Discharge
	 
	Section 4.01. Satisfaction and Discharge of Contingent Convertible Securities Indenture	20
	Section 4.02. Application of Trust Money	20
	Section 4.03. Repayment to Company	20

 

    	i

     

    

 

	Article 5
	Remedies
	 	 

	Section 5.01. Enforcement Events	21
	Section 5.02. Collection of Indebtedness and Suits for Enforcement by Trustee	21
	Section 5.03. Trustee May File Proofs of Claim	21
	Section 5.04. Trustee May Enforce Claims without Possession of Contingent Convertible Securities	21
	Section 5.05. Application of Money Collected	21
	Section 5.06. Limitation on Suits	22
	Section 5.07. Unconditional Right of Holders to Receive Principal and Interest, if any	22
	Section 5.08. Restoration of Rights and Remedies	22
	Section 5.09. Rights and Remedies Cumulative	22
	Section 5.10. Delay or Omission Not Waiver	22
	Section 5.11. Control by Holders	22
	Section 5.12. Undertaking for Costs	23
	 	 
	Article 6
	The Trustee
	 
	Section 6.01. Duties of Trustee	23
	Section 6.02. Rights of Trustee	24
	Section 6.03. Trustee’s Disclaimer	25
	Section 6.04. Notice of Enforcement Events	25
	Section 6.05. May Hold Contingent Convertible Securities	25
	Section 6.06. Money Held in Trust	25
	Section 6.07. Compensation and Indemnity	25
	Section 6.08. Disqualification; Conflicting Interests	26
	Section 6.09. Corporate Trustee Required; Eligibility	26
	Section 6.10. Resignation and Removal; Appointment of Successor	26
	Section 6.11. Successor Trustee by Merger	27
	Section 6.12. Eligibility; Disqualification	27
	Section 6.13. Preferential Collection of Claims against the Company	27
	Section 6.14. Appointment of Co-Trustee	27
	Section 6.15. Appointment of Authenticating Agent	28
	 	 
	Article 7
	Holders Lists and Reports by Trustee and Company
	 
	Section 7.01. Company to Furnish Trustee Names and Addresses of Holders	29
	Section 7.02. Preservation of Information; Communication to Holders	29
	Section 7.03. Reports by Trustee	29
	Section 7.04. Reports by Company	30
	 	 
	Article 8
	Supplemental Indentures
	 
	Section 8.01. Banco de México Authorization	30
	Section 8.02. Supplemental Indenture without Consent of Holders	30
	Section 8.03. Supplemental Indentures with Consent of Holders	31
	Section 8.04. Execution of Supplemental Indentures	32
	Section 8.05. Effect of Supplemental Indentures	32
	Section 8.06. Conformity with Trust Indenture Act	32
	Section 8.07. Reference in Contingent Convertible Securities to Supplemental Indentures	32
	Section 8.08. Notification of Modification or Supplemental Indenture	32
	 	 
	Article 9
	Covenants
	 
	Section 9.01. Payment of Principal and Interest	32
	Section 9.02. Maintenance of Office or Agency	32
	Section 9.03. Money for Payments to Be Held in Trust	33

 

    	ii

     

    

	Section 9.04. Corporate Existence	33
	Section 9.05. Maintenance of Approvals	33
	Section 9.06. Statement as to Compliance	33
	Section 9.07. Original Issue Document	34
	 	 
	Article 10
	Redemption of Contingent Convertible Securities
	 
	Section 10.01. Applicability of Article	34
	Section 10.02. Election to Redeem; Notice to Trustee	34
	Section 10.03. Accrual of Interest	34
	Section 10.04. Selection by Trustee of Contingent Convertible Securities to Be Redeemed	34
	Section 10.05. Notice of Redemption	34
	Section 10.06. Deposit of Redemption Price	34
	Section 10.07. Contingent Convertible Securities Payable on Redemption Date	35
	Section 10.08. Contingent Convertible Securities Redeemed in Part	35
	 	 
	Article 11
	Subordination of Contingent Convertible Securities
	 
	Section 11.01. Contingent Convertible Securities Subordinate to Certain Other Claims of Creditors of the Company	35
	Section 11.02. Provisions Solely to Define Relative Rights	36
	Section 11.03. Trustee to Effectuate Subordination	36
	Section 11.04. No Waiver of Subordination Provisions	36
	Section 11.05. Notice to Trustee	36
	Section 11.06. Reliance on Judicial Order or Certificate of Liquidating Agent	36
	Section 11.07. Trustee Not Fiduciary for Senior Creditors	36
	Section 11.08. Rights of Trustee as Senior Creditor; Preservation of Trustee’s Rights	37
	Section 11.09. Article Applicable to Paying Agents	37

 

    	iii

     

    

CONTINGENT CONVERTIBLE SECURITIES INDENTURE,
dated as of , between GRUPO FINANCIERO SANTANDER MÉXICO, S.A.B. de C.V., a publicly traded variable corporation (sociedad
anónima bursátil de capital variable) incorporated in accordance with the laws of the United Mexican States (the
“Company”) and THE BANK OF NEW YORK MELLON, a banking corporation duly organized and existing under the laws
of the State of New York as trustee (together with its successors hereunder, the “Trustee”), transfer agent
(in such capacity, together with its successors hereunder, the “Transfer Agent”), contingent convertible security
registrar (in such capacity, together with its successors hereunder, the “Contingent Convertible Security Registrar”)
and as paying agent (in such capacity, together with its successors hereunder, the “Paying Agent”).

 

RECITALS OF THE COMPANY

 

WHEREAS, the Company has duly authorized
the execution and delivery of this Contingent Convertible Securities Indenture to provide for the issuance from time to time of
its Contingent Convertible Securities (herein called the “Contingent Convertible Securities”), to be issued
in one series only, represented by one or more Global Securities in registered form without coupons for payments attached, or represented
by definitive Contingent Convertible Securities in registered form without coupons for payments attached, the amount and terms
of such series to be determined as hereinafter provided; and

 

WHEREAS, all things necessary to make this
Contingent Convertible Securities Indenture a valid and binding agreement of the Company, in accordance with its terms, have been
done;

 

NOW, THEREFORE, THIS CONTINGENT CONVERTIBLE
SECURITIES INDENTURE WITNESSETH:

 

For and in consideration of the premises
and the purchase of the Contingent Convertible Securities by the Holders thereof, the Company and the Trustee mutually covenant
to and agree for the equal and proportionate benefit of all Holders of Contingent Convertible Securities as follows:

 

Article
1

Definitions and Other Provisions of General Application

 

Section 1.01. Definitions. For all
purposes of this Contingent Convertible Securities Indenture, except as otherwise expressly provided or unless the context otherwise
requires

 

(a) the terms defined in this
Article have the meanings assigned to them in this Article and include the plural as well as the singular;

 

(b) all other terms used herein
which are defined in the Trust Indenture Act, either directly or by reference therein, have the meanings assigned to them therein;

 

(c) all accounting terms not otherwise
defined herein have the meanings assigned to them in accordance with generally accepted accounting principles and, except as otherwise
herein expressly provided, the term “generally accepted accounting principles” with respect to any computation required
or permitted hereunder shall mean the accounting principles and regulations prescribed by the CNBV for banks in Mexico, as amended
from time to time, at the date of such computation and as applied by the Company;

 

(d) the words “herein”,
“hereof” and “hereunder” and other words of similar import refer to this Contingent Convertible Securities
Indenture as a whole and not to any particular Article, Section or other subdivision; and

 

(e) unless the context requires,
any reference to an “Article” or a “Section” refers to an Article or Section of this Contingent Convertible
Securities Indenture.

 

“Act”, when used with
respect to any Holder, has the meaning specified in ‎Section
1.04.

 

“Additional Notes” has
the meaning set forth in ‎Section 3.12.

 

“Additional Tier 1 Capital (capital
básico no fundamental)” means the amount of the non-core capital of Tier 1 Capital (capital básico),
as such term is determined based on the Mexican Capitalization Requirements, also known as non-fundamental basic capital (capital
básico no fundamental), as such determination may be amended from time to time.

 

“Affiliate” of any specified
Person means any other Person directly or indirectly controlling or controlled by or under direct or indirect common control with
such specified Person. For the purposes of this definition, “control” when used with respect to any specified Person
means the power to direct the management and policies of such Person, directly or indirectly, whether through the ownership of
voting securities, by contract or otherwise; and the terms “controlling” and “controlled” have meanings
correlative to the foregoing.

 

“Agent Member” means
a member of, or participant in, any Depositary.

 

    1

     

    

“Authenticating Agent”
means any Person authorized by the Trustee to act on behalf of the Trustee to authenticate Contingent Convertible Securities. Initially,
the Trustee shall act as Authenticating Agent.

 

“Authorized Newspaper”
means a newspaper in an official language of the country of publication customarily published at least once a day for at least
five days in each calendar week and of general circulation in the place in connection with which the term is used, which, in Mexico,
will be the Reforma, if practicable, and which, in the United States, will be the Wall Street Journal, if practicable, and which,
in the country in which the Contingent Convertible Securities are listed, if any, will be any such publication in the jurisdiction
where such stock exchange is located, and if it shall be impracticable in the opinion of the Company or the Trustee, as applicable
to make any publication of any notice required hereby in any such newspaper, shall mean any publication or other notice in lieu
thereof which is made or given with the approval of the Company or the Trustee, as applicable, which may include publication or
other notice to members through DTC and INDEVAL.

 

The “Bank” means Banco
Santander (México), S.A., Institución de Banca Múltiple, Grupo Financiero Santander México, the Company’s
licensed banking subsidiary.

 

“Board of Directors”
means either the board of directors, or any committee of such board duly authorized to act with respect hereto, of the Company,
which board of directors or committee may, to the extent permitted by applicable law, delegate its authority.

 

“Board Resolution” means
a copy of a resolution certified by the Secretary or a Deputy or Assistant Secretary of the Company to have been duly adopted by
the Board of Directors or an authorized committee thereof and to be in full force and effect on the date of such certification
and delivered to the Trustee.

 

“Business Day” means
any day other than a Saturday or a Sunday, or a day on which banking institutions in The City of New York or Mexico City are authorized
or required by law, regulation or executive order to remain closed.

 

“Calculation Agent” means
the Person, if any, authorized by the Company to calculate the interest rate or other amounts from time to time in relation to
the series of Contingent Convertible Securities.

 

A “Capital Event” shall
occur if, in the Company’s reasonable determination, that, as a result of (a) the occurrence of any amendment to or change
in the laws or any regulations thereunder of Mexico or (b) any official administrative pronouncement or judicial decision interpreting
or applying these laws or regulations, which amendment or change is effective or which pronouncement or decision is announced on
or after the issue date of the series of Contingent Convertible Securities, there is more than an insubstantial risk that the Bank
will not be entitled to treat any such Contingent Convertible Securities as Tier 1 Capital (capital básico), or the
then-equivalent of Tier 1 Capital (capital básico) for purposes of the Mexican Capitalization Requirements, as then
in effect and applicable to the Bank.

 

“Capital Supplement”
means the Countercyclical Capital Supplement and the D-SIBs Capital Supplement, together with any other additional capital conservation
or loss absorbency capital requirement to be constituted by the banks pursuant to the Mexican Banking Law and the Mexican Capitalization
Requirements.

 

“Clearstream” means Clearstream
Banking, société anonyme, or its nominee or its or their successor.

 

“CNBV” means the Mexican
National Banking and Securities Commission (Comisión Nacional Bancaria y de Valores) or any successor thereof.

 

“Commission” means the
United States Securities and Exchange Commission, as from time to time constituted, created under the Exchange Act, or, if at any
time after the execution of this instrument such Commission is not existing and performing the duties now assigned to it under
the Trust Indenture Act, then the body performing such duties at such time.

 

“Company” means the Person
named as the “Company” in the first paragraph of this Contingent Convertible Securities Indenture until a successor
corporation shall have become such pursuant to the applicable provisions of this Contingent Convertible Securities Indenture, and
thereafter “Company” shall mean such successor corporation.

 

“Company Request” and
“Company Order” mean, respectively, a written request or order signed in the name of the Company by an Executive
Officer and delivered to the Trustee.

 

“Contingent Convertible Securities”
has the meaning set forth in the recitals of the Company herein and more particularly means the series of Contingent Convertible
Securities issued, authenticated and delivered under this Contingent Convertible Securities Indenture.

 

“Contingent Convertible Securities
Indenture” means this instrument as originally executed or as it may from time to time be supplemented or amended by
one or more indentures supplemental hereto entered into pursuant to the applicable provisions hereof and shall include the terms and forms of the series of Contingent
Convertible Securities established pursuant to ‎Section
3.01.

 

    2

     

    

 

“Contingent Convertible Security”
means one of the Contingent Convertible Securities.

 

“Contingent Convertible Security
Register” and “Contingent Convertible Security Registrar” have the respective meanings specified in
‎Section 3.05.

 

“Corporate Trust Office”
means the office of the Trustee in which its corporate trust business is principally administered, which, with respect to The Bank
of New York Mellon is currently located at 101 Barclay Street, Floor 7-E, New York, NY 10286 (Attention: International Corporate
Trust, Facsimile: (212) 815-5366).

 

The term “corporation”
includes corporations, associations, companies and business trusts.

 

“Countercyclical Capital Supplement”
means any applicable additional countercyclical amount of capital that may be required from banks, as determined by the CNBV pursuant
to the Mexican Banking Law and the Mexican Capitalization Requirements.

 

“D-SIB” means any domestic
systemically important bank, as determined by the CNBV annually pursuant to the Mexican Banking Law and the Mexican Capitalization
Requirements.

 

“D-SIBs Capital Supplement”
means the additional loss absorbency capital to be constituted by D-SIBs to reflect the greater risk that they pose to the domestic
financial system, as determined by the CNBV pursuant to the Mexican Banking Law and the Mexican Capitalization Requirements.

 

“Depositary” means, with
respect to Contingent Convertible Securities of the series issuable or issued in whole or in part in the form of one or more Global
Securities in registered form, a clearing agency that is designated to act as depositary for such Global Securities as contemplated
by ‎Section 3.05(a).

 

“Dollar” or “$”
or any similar reference means the coin or currency of the United States which as at the time of payment is legal tender for the
payment of public and private debts.

 

“DTC” means The Depository
Trust Company or its nominee or its or their successor.

 

“Enforcement Event” has
the meaning specified in ‎Section 5.01.

 

“Euroclear” means the
Euroclear Bank S.A./N.V. as operator of the Euroclear system, or its nominee or its or their successor.

 

“Exchange Act” means
the United States Securities Exchange Act of 1934, as amended.

 

“Executive Officer” means,
with respect to the Company, the chairman of the Board of Directors, the president or chief executive officer, any executive vice
president, any senior vice president, any vice president, the chief financial officer, the treasurer or any assistant treasurer,
or the secretary or any assistant secretary.

 

“Foreign Currency” means
the Mexican peso or any currency issued by the government of any country (or a group of countries or participating member states)
other than the United States which as at the time of payment is legal tender for the payment of public and private debts.

 

“Foreign Government Securities”
means with respect to Contingent Convertible Securities of the series that are denominated in a Foreign Currency, non-callable
(i) direct obligations of the participating member state or government that issued such Foreign Currency for the payment of which
obligations its full faith and credit is pledged or (ii) obligations of a Person controlled or supervised by and acting as an agency
or instrumentality of such participating member state or government, the payment of which obligations is unconditionally guaranteed
as a full faith and credit obligation of such participating member state or government. For the avoidance of doubt, for all purposes
hereof, pesos shall be deemed to have been issued by each participating member state from time to time.

 

“Fundamental Capital (capital
fundamental)” means capital fundamental, as calculated pursuant to the applicable Mexican Capitalization Requirements.

 

“Global Security” means
a global certificate evidencing all or part of the series of Contingent Convertible Securities, authenticated and delivered to
or on behalf of the Holder and registered in the name of the Holder or its nominee.

 

“Group” means Grupo Financiero
Santander México, S.A.B. de C.V., together with its consolidated subsidiaries.

 

“Holder” means a Person
in whose name a Contingent Convertible Security in global or definitive form is registered in the Contingent Convertible Security
Register.

 

“INDEVAL” means S.D.
Indeval Institución para el Depósito de Valores, S.A. de C.V.

 

    3

     

    

“Interest Payment Date”,
when used with respect to any Contingent Convertible Security, means the Stated Maturity, if any, of any installment of interest
on such Contingent Convertible Security.

 

“Liquidation Event” shall
have the meaning specified in a supplemental indenture with respect to the series of Contingent Convertible Securities.

 

“Maturity”, when used
with respect to any Contingent Convertible Security, means the date, if any, on which the principal of such Contingent Convertible
Security becomes due and payable as therein or herein provided, whether by call for redemption, winding-up of the Company or otherwise.

 

“Mexican Banking Law”
means the Ley de Instituciones de Crédito of Mexico, as replaced or amended, or any successor thereof.

 

“Mexican Bankruptcy Law”
means the Ley de Concursos Mercantiles, as replaced or amended, or any successor thereof.

 

“Mexican Capitalization Requirements”
means the capitalization requirements for commercial banks set forth under the Mexican Banking Law and the general rules applicable
to Mexican banks, as such laws and regulations may be amended or superseded.

 

“Mexican Financial Groups Law”
means the Ley para Regular las Agrupaciones Financieras, as replaced or amended, or any successor thereof.

 

“Mexican Securities Market Law”
means the Ley del Mercado de Valores, as replaced or amended, or any successor thereof.

 

“Mexico” means the United
Mexican States.

 

“Officer’s Certificate”
means a certificate delivered to the Trustee and signed by an Executive Officer.

 

“Opinion of Counsel”
means a written opinion of counsel, who may be an employee of or legal advisors for the Company or other legal advisors reasonably
acceptable to the Trustee.

 

“Ordinary Shares” means
the Company’s Series B and Series F shares, collectively.

 

“Original Issue Discount Security”
means any Contingent Convertible Security that provides for an amount less than the principal amount to be due and payable upon
a declaration of the Maturity thereof.

 

“Outstanding”, when used
with respect to Contingent Convertible Securities or the series of Contingent Convertible Securities means (except as otherwise
specified pursuant to ‎Section 3.01), as of
the date of determination, all Contingent Convertible Securities or all Contingent Convertible Securities of such series, as the
case may be, theretofore authenticated and delivered under this Contingent Convertible Securities Indenture, except

 

(i) Contingent Convertible Securities
theretofore canceled by the Trustee or delivered to the Trustee for cancellation;

 

(ii) Contingent Convertible Securities,
or portions thereof, for whose payment or redemption money, U.S. Government Obligations or Foreign Government Securities in the
necessary amount have been theretofore deposited with the Trustee or any Paying Agent (other than the Company) in trust or set
aside and segregated in trust by the Company (if the Company shall act as its own Paying Agent) for the Holders of such Contingent
Convertible Securities; provided that, if such Contingent Convertible Securities are to be redeemed, notice of such redemption
has been duly given pursuant to this Contingent Convertible Securities Indenture or provision therefor satisfactory to the Trustee
has been made; and

 

(iii) Contingent Convertible Securities
which have been paid pursuant to ‎Section
10.06 or in exchange for or in lieu of which other Contingent Convertible Securities or Ordinary Shares delivered pursuant to this
Contingent Convertible Securities Indenture, other than any such Contingent Convertible Securities in respect of which there shall
have been presented to the Trustee proof satisfactory to it that such Contingent Convertible Securities are held by a bona fide
purchaser in whose hands such Contingent Convertible Securities are valid obligations of the Company;

 

provided, however, that in determining whether the Holders of
the requisite principal amount of the Outstanding Contingent Convertible Securities of the series have given any request, demand,
authorization, direction, notice, consent or waiver hereunder, (i) the principal amount of a Contingent Convertible Security denominated
in a Foreign Currency shall be the Dollar equivalent, determined on the date of original issuance of such Contingent Convertible
Security, of the principal amount of such Contingent Convertible Security; and (ii) Contingent Convertible Securities beneficially
owned by the Company or any other obligor upon the Contingent Convertible Securities or any Affiliate of the Company or of such
other obligor shall be disregarded and deemed not to be Outstanding except that, in determining whether the Trustee shall be protected
in relying upon any such request, demand, authorization, direction, notice, consent or waiver, only Contingent Convertible Securities
for which a Responsible Officer of the Trustee has received an Officer’s Certificate stating that such Contingent Convertible
Securities are so beneficially owned shall be so disregarded;

 

    4

     

    

provided, further, however, that Contingent
Convertible Securities so beneficially owned which have been pledged in good faith may be regarded as Outstanding if the pledgee
establishes to the satisfaction of the Trustee the pledgee’s right so to act with respect to such Contingent Convertible
Securities and that the pledgee is not the Company or any other obligor upon the Contingent Convertible Securities or any Affiliate
of the Company or of such other obligor.

 

“Paying Agent” means
any Person (which may include the Company) authorized by the Company to pay the principal of or interest, if any, on any Contingent
Convertible Securities on behalf of the Company.

 

“Person” means any individual,
corporation, partnership, joint venture, association, joint-stock company, trust, unincorporated organization or government or
any agency or political subdivision thereof or other entity.

 

“pesos” means Mexican
pesos, the legal currency in Mexico.

 

“Place of Payment”, when
used with respect to the Contingent Convertible Securities of the series, means the place or places where the principal of and
interest, if any, on the Contingent Convertible Securities of that series are payable as specified pursuant to ‎Section
3.01 or, if not so specified, as specified in ‎Section
9.02.

 

“Predecessor Security”
of any particular Contingent Convertible Security means every previous Contingent Convertible Security evidencing all or a portion
of the same debt as that evidenced by such particular Contingent Convertible Security; and, for the purposes of this definition,
any Contingent Convertible Security authenticated and delivered under ‎Section
3.06 in exchange for or in lieu of a mutilated, destroyed, lost or stolen Contingent Convertible Security shall be deemed to evidence
the same debt as the mutilated, destroyed, lost or stolen Contingent Convertible Security.

 

“Redemption Date”, when
used with respect to any Contingent Convertible Security to be redeemed, means the date fixed for such redemption as specified
in accordance with ‎Section 3.01.

 

“Redemption Price”, when
used with respect to any Contingent Convertible Security to be redeemed, means the price at which it is to be redeemed as specified
in accordance with ‎Section 3.01.

 

“Regular Record Date”
for the interest payable on any Interest Payment Date on registered Contingent Convertible Securities of the series means the date
specified for the purpose pursuant to ‎Section
3.01.

 

“Responsible Officer”,
when used with respect to the Trustee, means any officer of the Trustee assigned to or working in the Corporate Trust Department
of the Trustee or, with respect to a particular corporate trust matter, any other officer to whom such matter is referred because
of his or her knowledge of and familiarity with the particular subject and who shall have direct responsibility for the administration
of this Contingent Convertible Securities Indenture.

 

“Senior Creditors” means
creditors of the Company (i) who are unsubordinated creditors, (ii) whose claims are, or are expressed to be, subordinated (whether
only in the event of a Liquidation Event or otherwise) to the claims of unsubordinated creditors of the Company but not further
or otherwise, or (iii) who are subordinated creditors of the Company (whether as aforesaid or otherwise), other than those whose
claims rank, or are expressed to rank, pari passu with, or junior to, the claims of holders of the series of the Contingent Convertible
Securities and/or pari passu with or junior to any claims ranking pari passu with the claims of holders of the series of the Contingent
Convertible Securities, in each case, in a Liquidation Event and (iv) any other creditors identified as Senior Creditors with respect
to Contingent Convertible Securities of such series pursuant to ‎Section
3.01.

 

“Stated Maturity”, when
used with respect to any Contingent Convertible Security or any installment of principal thereof or interest thereon, means the
date, if any, specified in, or determined in accordance with the terms of, such Contingent Convertible Security as the fixed date
on which the principal or interest (as the case may be) of such Contingent Convertible Security is due and payable.

 

“Tier 1 Capital (capital básico)”
means the basic capital (capital básico) of the Total Net Capital (capital neto), as such term is determined
based on the Mexican Capitalization Requirements, as such determination may be amended from time to time, which is comprised of
Fundamental Capital (capital fundamental) and Additional Tier 1 Capital (capital básico no fundamental).

 

“Tier 2 Capital (capital complementario)”
means the additional capital (capital complementario) of the Total Net Capital (capital neto), as such term is determined
based on the Mexican Capitalization Requirements, as such determination may be amended from time to time.

 

“Total Net Capital (capital
neto)” means capital neto, as such term is determined based on the Mexican Banking Law and the Mexican Capitalization
Requirements, also known as Tier 1 Capital (capital básico) plus Tier 2 Capital (capital complementario),
as such determination may be amended from time to time.

 

    5

     

    

“Transfer Agent” means
the Person named as the “Transfer Agent” in the first paragraph of this instrument until a successor transfer agent
shall have become such pursuant to the applicable provisions of this Contingent Convertible Securities Indenture, and thereafter
“Transfer Agent” shall mean the Person who is then the Transfer Agent hereunder, and if at any time there is more than
one such Person, “Transfer Agent” shall mean and include each such Person; and “Transfer Agent” as used
with respect to the Contingent Convertible Securities of the series shall mean the Transfer Agent with respect to the Contingent
Convertible Securities of such series.

 

“Trust Indenture Act”
or the “TIA” means the Trust Indenture Act of 1939, as amended by the Trust Indenture Reform Act of 1990, as
in force at the date as of which this instrument was executed, except as provided in ‎Section
8.06.

 

“Trustee” means the Person
named as the “Trustee” in the first paragraph of this instrument until a successor trustee shall have become such pursuant
to the applicable provisions of this Contingent Convertible Securities Indenture, and thereafter “Trustee” shall mean
the Person who is then the Trustee hereunder, and if at any time there is more than one such Person, “Trustee” shall
mean and include each such Person; and “Trustee” as used with respect to the Contingent Convertible Securities of the
series shall mean the Trustee with respect to the Contingent Convertible Securities of such series.

 

“Trust Officer” means,
when used with respect to the Trustee, any officer within the Corporate Trust Office of the Trustee, located at the Corporate Trust
Office, including any director, vice president, assistant vice president, assistant secretary, assistant treasurer, trust officer
or any other officer of the Trustee, who shall have direct responsibility over the administration of this Contingent Convertible
Securities Indenture, and for the purposes of ‎Section
6.01(a) shall also include any other officer of the Trustee to whom any corporate trust matter is referred because of such person’s
knowledge of and familiarity with the particular subject.

 

“United States” and “U.S.”
mean the United States of America and its territories and possessions.

 

“U.S. Government Obligations”
means non-callable (i) direct obligations of the United States for which its full faith and credit are pledged and/or (ii) obligations
of a Person controlled or supervised by and acting as an agency or instrumentality of the United States, the payment of which is
unconditionally guaranteed as a full faith and credit obligation of the United States, and shall also include a depository receipt
issued by a bank (as defined in Section 3(a)(2) of the Securities Act of 1933, as amended), which may include the Trustee, as custodian
with respect to any such U.S. Government Obligation or a specific payment of principal of or interest on any such U.S. Government
Obligation held by such custodian for the account of the holder of such depository receipt, provided that (except as required by
law) such custodian is not authorized to make any deduction from the amount payable to the holder of such depository receipt from
any amount received by the custodian in respect of the U.S. Government Obligation or the specific payment of principal of or interest
on the U.S. Government Obligation evidenced by such depository receipt.

 

“U.S. Legal Tender” means
such coin or currency of the United States as at the time of payment shall be legal tender for the payment of public and private
debts.

 

Section 1.02. Compliance Certificates
and Opinions. Except as otherwise expressly provided by this Contingent Convertible Securities Indenture, upon any application
or request by the Company to the Trustee to take any action under any provision of this Contingent Convertible Securities Indenture,
the Company shall furnish to the Trustee an Officer’s Certificate stating that all conditions precedent, if any, provided
for in this Contingent Convertible Securities Indenture relating to the proposed action have been complied with and an Opinion
of Counsel stating that in the opinion of the legal advisor rendering such opinion all such conditions precedent, if any, have
been complied with, except that in the case of any such application or request as to which the furnishing of such documents is
specifically required by any provision of this Contingent Convertible Securities Indenture relating to such particular application
or request, no additional certificate or opinion need be furnished.

 

Every certificate or opinion with respect
to compliance with a condition or covenant provided for in this Contingent Convertible Securities Indenture shall include

 

(a) a statement that each Person signing
such certificate or opinion has read such covenant or condition and the definitions herein relating thereto;

 

(b) a brief statement as to the nature and
scope of the examination or investigation upon which the statements or opinions contained in such certificate or opinion are based;

 

(c) a statement that, in the opinion of
each such Person, he or she has made such examination or investigation as is necessary to enable him or her to express an informed
opinion as to whether or not such covenant or condition has been complied with; and

 

(d) a statement as to whether, in the opinion
of each such Person, such condition or covenant has been complied with.

 

Section 1.03. Form of Documents Delivered
to the Trustee. In any case where several matters are required to be certified by, or covered by an opinion of, any specified
Person, it is not necessary that all such matters be certified by, or covered by the opinion of, only one such Person, or that
they be so certified or covered by only one document, but one such Person may certify or give an opinion with respect to some matters
and one or more other such Persons as to other matters, and any such Person may certify or give an opinion as to such matters in
one or several documents.

 

    6

     

    

Any certificate or opinion of an officer
of the Company may be based, insofar as it relates to legal matters, upon a certificate or opinion of, or representations by, legal
advisors, unless such officer knows, or in the exercise of reasonable care should know, that the certificate or opinion or representations
with respect to the matters upon which his certificate or opinion is based are erroneous. Any such certificate or opinion of, or
representations by, legal advisors may be based, insofar as it relates to factual matters, upon a certificate or opinion of, or
representations by, an officer or officers of the Company stating that the information with respect to such factual matters is
in the possession of the Company, unless such legal advisors know, or in the exercise of reasonable care should know, that the
certificate or opinion or representation with respect to such matters is erroneous.

 

Where any Person is required to make, give
or execute two or more applications, requests, consents, certificates, statements, opinions or other instruments under this Contingent
Convertible Securities Indenture, they may, but need not, be consolidated and form one instrument.

 

Section 1.04. Acts of Holders. (a)
Any request, demand, authorization, direction, notice, consent, waiver or other action provided by this Contingent Convertible
Securities Indenture to be given or taken by Holders may be embodied in and evidenced by one or more instruments of substantially
similar tenor signed by such Holders in person or by an agent duly appointed in writing; and, except as herein otherwise expressly
provided, such action shall become effective when such instrument or instruments are delivered to the Trustee and, when it is hereby
expressly required, to the Company. Such instrument or instruments (and the action embodied therein and evidenced thereby) are
herein sometimes referred to as the “Act” of the Holders signing such instrument or instruments. Proof of execution
of any such instrument or of a writing appointing any such agent shall be sufficient for any purpose of this Contingent Convertible
Securities Indenture and (subject to ‎Section 6.01) conclusive in favor of the Trustee and the Company, if made in the manner
provided in this Section.

 

(a) The fact and date of the execution by
any Person of any such instrument or writing may be proved by the affidavit of a witness of such execution or by a certificate
of a notary public or other officer authorized by law to take acknowledgments of deeds, certifying that the individual signing
such instrument or writing acknowledged to him or her the execution thereof. When such execution is by a signer acting in a capacity
other than his individual capacity, such certificate or affidavit shall also constitute sufficient proof of his authority. The
fact and date of the execution of any such instrument or writing, or the authority of the Person executing the same, may also be
proved in any other manner which the Trustee deems sufficient.

 

(b) The ownership of Contingent Convertible
Securities shall be proved by the Contingent Convertible Security Register.

 

(c) Any request, demand, authorization,
direction, notice, consent, waiver or other Act of the Holder of any Contingent Convertible Security shall bind every future Holder
of the same Contingent Convertible Security and the Holder of every Contingent Convertible Security issued upon the registration
of transfer thereof or in exchange therefor or in lieu thereof in respect of anything done, omitted or suffered to be done by the
Trustee or the Company in reliance thereon, whether or not notation of such action is made upon such Contingent Convertible Security
or such other Contingent Convertible Security.

 

(d) If the Company shall solicit from the
Holders any request, demand, authorization, direction, notice, consent, waiver or other Act, the Company may, at its option, by
or pursuant to a Board Resolution or an Officer’s Certificate, fix in advance a record date for the determination of Holders
entitled to give such request, demand, authorization, direction, notice, consent, waiver or other Act, but the Company shall have
no obligation to do so. If such a record date is fixed, such request, demand, authorization, direction, notice, consent, waiver
or other Act may be given before or after such record date, but only the Holders of record at the close of business on such record
date shall be deemed to be Holders for the purposes of determining whether Holders of the requisite proportion of outstanding Contingent
Convertible Securities have authorized or agreed or consented to such request, demand, authorization, direction, notice, consent,
waiver or other Act, and for that purpose the outstanding Contingent Convertible Securities shall be computed as of such record
date; provided that no such authorization, agreement or consent by the Holders on such record date shall be deemed effective unless
it shall become effective pursuant to the provisions of this Contingent Convertible Securities Indenture not later than six months
after the record date.

 

Section 1.05. Notices, Etc. to Trustee
and Company. Any request, demand, authorization, direction, notice, consent, waiver or Act of Holders or other document provided
or permitted by this Contingent Convertible Securities Indenture to be made upon, given or furnished to, or filed with,

 

(a) the Trustee by any Holder or by the
Company shall be sufficient for every purpose hereunder (unless otherwise herein expressly provided) if made, given, furnished
or filed in writing (which may be via facsimile) in the English language to the Trustee at its Corporate Trust Office with a copy
to The Bank of New York Mellon, International Corporate Trust, 101 Barclay Street, Floor 7-East, New York, NY 10286, Facsimile:
(212) 815-5366;

 

(b) the Company by the Trustee or by any
Holder shall be sufficient for every purpose hereunder (unless otherwise herein expressly provided) if in writing and mailed, in
the case of the Company, first-class postage prepaid, addressed to it at the address of its principal executive offices at Av.
Prolongación Paseo de la Reforma 500, Colonia Lomas de Santa Fe, Delegación Álvaro Obregón 01219, Mexico
City, marked “Attention: Chief Financial Officer/General Counsel”.

 

    7

     

    

The Trustee agrees to accept and act upon
instructions or directions pursuant to this Contingent Convertible Securities Indenture sent by unsecured email, portable document
format (PDF), facsimile transmission or other similar unsecured electronic methods; provided, however, that the Trustee shall have
received from the Company an incumbency certificate listing persons designated to give such instructions or directions and containing
the titles and specimen signatures of such designated persons; which such incumbency certificate shall be amended and replaced
whenever a person is to be added or deleted from the listing. If the Company elects to give the Trustee email or facsimile instructions
(or instructions by a similar electronic method) and the Trustee in its discretion elects to act upon such instructions, the Trustee’s
understanding of such instructions shall be deemed controlling. The Trustee shall not be liable for any losses, costs or expenses
arising directly or indirectly from the Trustee’s reliance upon and compliance with such instructions notwithstanding a conflict
or inconsistency between such instructions and a subsequent written instruction. The Company agrees to assume all risks arising
out of the use of such electronic methods to submit instructions and directions to the Trustee, including, without limitation,
the risk of the Trustee acting on unauthorized instructions, and the risk of interception and misuse by third parties.

 

Section 1.06. Notice to Holders; Waiver.
When this Contingent Convertible Securities Indenture provides for notice to Holders of any event, such notice shall be sufficiently
given (unless otherwise herein expressly provided) if given in writing and mailed, first-class postage prepaid, to each Holder
of a Contingent Convertible Security affected by such event in the manner and to the extent provided in Section 313(c) of the Trust
Indenture Act with respect to reports pursuant to ‎Section 7.03(a).

 

For so long as the Contingent Convertible
Securities of the series are represented by Global Securities, the Company shall deliver a copy of all notices with respect to
such series to the Holder through the Depositary, in accordance with its applicable procedures from time to time. Moreover, until
such time as any definitive securities are issued, there may, so long as any Global Securities representing the Contingent Convertible
Securities are held in their entirety on behalf of DTC, be substituted for such notice by first-class mail the delivery of the
relevant notice to DTC for communication by them to the Holders of the Contingent Convertible Securities, in accordance with DTC’s
applicable procedures and the procedures of its indirect participants. Otherwise, notices to the Holders shall be provided to the
addresses that appear on the Contingent Convertible Security Register.

 

Neither the failure to give any such notice,
nor any defect in any notice so given, to any particular Holder shall affect the sufficiency of such notice with respect to other
Holders. Where this Contingent Convertible Securities Indenture provides for notice in any manner, such notice may be waived in
writing by the Person entitled to receive such notice, either before or after the event, and such waiver shall be the equivalent
of such notice. Waivers of notice by Holders shall be filed with the Trustee, but such filing shall not be a condition precedent
to the validity of any action taken in reliance upon such waiver. In case by reason of the suspension of regular mail service or
by reason of any other cause it shall be impracticable to give such notice by mail, then such notification as shall be made with
the approval of the Trustee shall constitute a sufficient notification for every purpose hereunder.

 

If the Contingent Convertible Securities
are listed on a stock exchange and the rules of such stock exchange so require, all notices to Holders shall be published in an
Authorized Newspaper in the jurisdiction where such stock exchange is located.

 

Section 1.07. Conflict with Trust Indenture
Act. If any provision hereof limits, qualifies or conflicts with another provision hereof which is required to be included
in this Contingent Convertible Securities Indenture by any of the provisions of the Trust Indenture Act, such required provision
shall control. If at any future time any provision required to be included herein by the Trust Indenture Act as in force at the
date as of which this Contingent Convertible Securities Indenture was executed or any limitation imposed by the Trust Indenture
Act at such date on any provision otherwise included herein would not be so required or imposed (in whole or in part) if this Contingent
Convertible Securities Indenture were executed at such future time, the Company and the Trustee may enter into one or more indentures
supplemental hereto pursuant to ‎Section 8.02 to change or eliminate (in whole or in part) such provision or limitation of
this Contingent Convertible Securities Indenture in conformity with the requirements of the Trust Indenture Act as then in force,
except that (subject to ‎Article 8) no provision or limitation required to be included herein by Sections 310(a)(1) and (a)(2),
315(a), (c), (d)(1), (d)(2), (d)(3) and (e), 316(a)(1)(A), (a)(1)(B), (a)(2), (a) (last sentence) and (b) of the Trust Indenture
Act as in force at the date as of which this Contingent Convertible Securities Indenture was executed may be so changed or eliminated.

 

Section 1.08. Effect of Headings and
Table of Contents. The Article and Section headings herein and the Table of Contents are for convenience only and shall not
affect the construction hereof.

 

Section 1.09. Successors and Assigns.
All covenants and agreements in this Contingent Convertible Securities Indenture by the Company shall bind its successors and assigns,
whether so expressed or not.

 

Section 1.10. Separability Clause.
In case any provision in this Contingent Convertible Securities Indenture or in the Contingent Convertible Securities shall be
invalid, illegal or unenforceable, the validity, legality and enforceability of the remaining provisions shall not in any way be
affected or impaired thereby.

 

Section 1.11. Benefits of Contingent
Convertible Securities Indenture. Nothing in this Contingent Convertible Securities Indenture or in the Contingent Convertible
Securities, express or implied, shall give to any Person, other than the parties hereto and their successors hereunder, and the

 

    8

     

    

Holders of Contingent Convertible Securities,
any benefit or any legal or equitable right, remedy or claim under this Contingent Convertible Securities Indenture.

 

Section 1.12. Currency Indemnity.

 

(a) Unless otherwise specified pursuant
to ‎Section 3.01, U.S. Legal Tender is the sole currency of account and payment
for all sums payable by the Company under or in connection with the Contingent Convertible Securities or this Contingent Convertible
Securities Indenture, including damages. To the fullest extent permitted under applicable law, any amount received or recovered
pursuant to a judgment or order made by a court of any jurisdiction for the payment of any amount in respect of this Indenture
or any Contingent Convertible Securities in currency other than U.S. Legal Tender in respect of any sum expressed to be due to
it from the Company shall only constitute a discharge of such amounts due under the Contingent Convertible Securities and this
Indenture only to the extent of the U.S. Legal Tender amount which the recipient is able to purchase with the amount so received
or recovered in that other currency on the date of that receipt or recovery (or, if it is not practicable to make that purchase
on that date, on the first date on which it is practicable to do so). If that U.S. Legal Tender amount is less than the U.S. Legal
Tender amount expressed to be due to the recipient under the Contingent Convertible Securities or this Contingent Convertible Securities
Indenture, the Company shall, to the greatest extent permitted under applicable law, indemnify and hold harmless the recipient
against any deficiency sustained by it arising from any variation in rates of exchange between the date as of which that U.S. Legal
Tender amount is notionally converted into the judgment currency for purposes of the judgment or order and the date of actual payment.
For the purposes of this ‎Section 1.12, it shall be sufficient for the recipient
of a Contingent Convertible Security to certify that it would have suffered a loss had an actual purchase of U.S. Legal Tender
been made with the amount so received in that other currency on the date of receipt or recovery (or, if a purchase of U.S. Legal
Tender on such date had not been practicable, on the first date on which it would have been practicable).

 

(b) The indemnities of the Company contained
in this ‎Section 1.12, to the extent permitted by law: (i) constitute a separate
and independent obligation from the other obligations of the Company under this Contingent Convertible Securities Indenture and
the Contingent Convertible Securities; (ii) shall give rise to a separate and independent cause of action against the Company;
(iii) shall apply irrespective of any indulgence granted by any Holder of the Contingent Convertible Securities or the Trustee
from time to time; and (iv) shall continue in full force and effect notwithstanding any other judgment or order for a liquidated
sum or sums in respect of any amounts due under the Contingent Convertible Securities or this Contingent Convertible Securities
Indenture or any other judgment or order.

 

Section 1.13. Governing Law. This
Contingent Convertible Securities Indenture and the Contingent Convertible Securities shall be governed by, and construed in accordance
with, the law of the State of New York. Whether certain trigger events with respect to the series of Contingent Convertible Securities
as specified in a supplemental indenture have occurred is based upon applicable Mexican law or a determination by the applicable
Mexican regulator in accordance with Mexican law (as amended from time to time). Whether events permitting a redemption of the
series of Contingent Convertible Securities, as may be specified in a supplemental indenture, have occurred shall be governed by
and construed in accordance with Mexican law. Whether a Capital Event has occurred shall be determined by the Company, in accordance
with Mexican law (as amended from time to time). The ranking and subordination of the series of Contingent Convertible Securities
shall be governed by, and construed in accordance with, Mexican law (as amended from time to time). The parties hereto and each
Holder of a Note by its acceptance thereby, each hereby waives any rights it may have under the law of the State of New York not
to give effect to any such determination to the fullest extent permitted by applicable law. Any proceedings in respect of the Company’s
concurso mercantil or bankruptcy shall be conducted in accordance with the Mexican Bankruptcy Law and Chapter II of Title
Seven of the Mexican Financial Groups Law, and any merger or consolidation of the Company shall be subject to applicable approvals
under the Mexican Financial Groups Law and any other applicable Mexican laws, as replaced or amended from time to time or any successor
thereof.

 

Section 1.14. Submission to Jurisdiction;
Waiver of Immunities.

 

(a) Each of the parties hereto hereby consents
to the jurisdiction of the Supreme Court of the State of New York, County of New York and the United States District Court for
the Southern District of New York, each in the Borough of Manhattan, and agrees that all disputes under this Contingent Convertible
Securities Indenture may be submitted to the jurisdiction of such courts. Each party hereto irrevocably consents to and waives
to the fullest extent permitted by law any objection that it may have to the laying of venue of any suit, action or proceeding
against it or its properties, assets and revenues with respect to the Contingent Convertible Securities Indenture or any such suit,
action or proceeding in any such court and any right to which it may be entitled by virtue of its present or future domicile or
for any other reason.

 

(b) To the extent that the Company or any
of its revenues, assets or properties shall be entitled to any immunity from suit, from the jurisdiction of any such court, from
attachment prior to judgment, from attachment in aid of execution of judgment, from execution of a judgment or from any other legal
or judicial process remedy, it irrevocably agrees not to claim and irrevocably waives such immunity to the fullest extent permitted
by the laws of such jurisdiction.

 

Section 1.15. Saturdays, Sundays and
Legal Holidays. The terms of the Contingent Convertible Securities shall provide that, in any case where any Interest Payment
Date, Redemption Date, Maturity or Stated Maturity of a Contingent Convertible Security shall not be a Business Day at any Place
of Payment, then (notwithstanding any other provision of this Contingent Convertible Securities Indenture or the Contingent Convertible
Securities other than a provision in the Contingent Convertible Securities that specifically states that such provision shall apply
in lieu of this Section)

 

    9

     

    

payments of interest, if any, or principal
and the exchange of the Contingent Convertible Security need not be made on such date, but may be made on the next succeeding Business
Day (or such other Business Day as shall be provided in such Contingent Convertible Security) with the same force and effect as
if made on such Interest Payment Date, Redemption Date, Maturity or Stated Maturity; provided that no interest shall accrue on
such payment for the period from and after such Interest Payment Date, Redemption Date, Maturity or Stated Maturity, as the case
may be.

 

Section 1.16. Appointment of Agent for
Service. The Company has designated and appointed Banco Santander, S.A., New York Branch (“Banco Santander NY”),
with an address at 45 East 53rd Street, New York, NY 10022, as its authorized agent upon which process may be served in any suit
or proceeding in any Federal or State court in the Borough of Manhattan, The City of New York, New York, arising out of or relating
to the Contingent Convertible Securities or this Contingent Convertible Securities Indenture, but for that purpose only, and agrees
that service of process upon said Banco Santander NY shall be deemed in every respect effective service of process upon it in any
such suit or proceeding in any Federal or State court in the Borough of Manhattan, The City of New York, New York. Such appointment
shall be irrevocable so long as any of the Contingent Convertible Securities remain Outstanding until the appointment of a successor
by the Company and such successor’s acceptance of such appointment. Upon such acceptance, the Company shall notify the Trustee
of the name and address of such successor. The Company further agrees to take any and all action, including the execution and filing
of any and all such documents and instruments, as may be necessary to continue such designation and appointment of said Banco Santander
NY in full force and effect so long as any of the Contingent Convertible Securities shall be Outstanding. The Trustee shall not
be obligated and shall have no responsibility with respect to any failure by the Company to take any such action. The Company hereby
submits (for the purposes of any such suit or proceeding) to the jurisdiction of any such court in which any such suit or proceeding
is so instituted, and waives, to the extent it may effectively do so, any objection it may have now or hereafter to the laying
of the venue of any such suit or proceeding.

 

Section 1.17. Calculation Agent.
If the Company appoints a Calculation Agent pursuant to ‎Section 3.01 with respect to the series of Contingent Convertible
Securities, any determination of the interest rate on, or other amounts in relation to, such series of Contingent Convertible Securities
in accordance with the terms of such series of Contingent Convertible Securities by such Calculation Agent shall (in the absence
of manifest error, bad faith or willful misconduct) be binding on the Company, the Trustee and all Holders, and (in the absence
of manifest error, bad faith or willful misconduct) no liability to the Holders shall attach to the Calculation Agent in connection
with the exercise or non-exercise by it of its powers, duties and discretions.

 

Section 1.18. Waiver of Jury Trial. EACH
OF THE PARTIES HERETO HEREBY IRREVOCABLY WAIVES, TO THE FULLEST EXTENT PERMITTED BY APPLICABLE LAW, ANY AND ALL RIGHT TO TRIAL
BY JURY IN ANY LEGAL PROCEEDING ARISING OUT OF OR RELATING TO THIS CONTINGENT CONVERTIBLE SECURITIES INDENTURE, THE CONTINGENT
CONVERTIBLE SECURITIES OR THE TRANSACTIONS CONTEMPLATED HEREBY.

 

Article
2

Contingent Convertible Security Forms

 

Section 2.01. Forms Generally. The
Contingent Convertible Securities of the series shall be issuable as registered securities without coupons and in such forms as
shall be established by or pursuant to a Board Resolution, or an Officer’s Certificate, or in one or more indentures supplemental
hereto, pursuant to ‎Section 3.01, in each case with such insertions, omissions, substitutions and other variations as are
required or permitted by this Contingent Convertible Securities Indenture, and may have such letters, numbers or other marks of
identification and such legends or endorsements placed thereon as may be required to comply with any applicable law or rule or
regulation made pursuant thereto or with the rules of any securities exchange or Depositary therefor, or as may, consistently herewith,
be determined by the officers executing such Contingent Convertible Securities, all as evidenced by any such execution; provided,
however, that such Contingent Convertible Securities shall have endorsed thereon a statement in the following form or in substantially
the following form:

 

“The rights of the holder of the Contingent
Convertible Security are, to the extent and in the manner set forth in Section [ ] of the indenture supplemental to the Contingent
Convertible Securities Indenture establishing the terms of this Contingent Convertible Security, subordinated to the claims of
other creditors of the Company, and this Contingent Convertible Security is issued subject to the provisions of that Section [
], and the holder of this Contingent Convertible Security, by accepting the same, agrees to and shall be bound by such provisions.
Such provisions and the terms of this paragraph are governed by, and shall be construed in accordance with, the laws of Mexico.”

 

The Trustee’s certificates of authentication
shall be in substantially the form set forth in ‎Section
2.02 or ‎Section 6.15.

 

The definitive Contingent Convertible Securities
shall be printed, lithographed or engraved or produced by any combination of these methods or may be produced in any other manner
permitted by the rules of any securities exchange on which the Contingent Convertible Securities may be listed, all as determined
by the officers executing such Contingent Convertible Securities, as evidenced by their execution thereof.

 

Section 2.02. Form of Trustee’s
Certificate of Authentication. The Trustee’s certificate of authentication shall be in substantially the following form:

 

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CERTIFICATE OF AUTHENTICATION

 

This is one of the Contingent Convertible
Securities of the series designated herein referred to in the within-mentioned Contingent Convertible Securities Indenture.

 

	Dated:	 
	THE BANK OF NEW YORK MELLON, as Trustee
	 
	By:	 
	 	Authorized Signatory
	 	 	 

Article
3

The Contingent Convertible Securities

 

Section 3.01. Amount Unlimited, Issuable
in Series. The aggregate principal amount of Contingent Convertible Securities that may be authenticated and delivered under
this Contingent Convertible Securities Indenture is unlimited. The Contingent Convertible Securities may be issued in one series
only. No series of Contingent Convertible Securities may be issued, at any time, unless the Company has obtained prior authorization
from Banco de México to issue the series. This Contingent Convertible Securities Indenture is not intended to be,
and shall not be construed to be, a basis of a program for ongoing issuances of Contingent Convertible Securities.

 

There shall be established by or pursuant
to a Board Resolution, an Officer’s Certificate or established in one or more indentures supplemental hereto, prior to the
initial issuance of the series of Contingent Convertible Securities hereunder,

 

(a) the title of the Contingent Convertible
Securities of the series (which shall distinguish the Contingent Convertible Securities of the series from all other Contingent
Convertible Securities);

 

(b) any limit upon the aggregate principal
amount of the Contingent Convertible Securities of the series that may be authenticated and delivered under this Contingent Convertible
Securities Indenture (except for Contingent Convertible Securities authenticated and delivered upon registration of transfer of,
or in exchange for, or in lieu of, other Contingent Convertible Securities of the series pursuant to ‎Section
3.04, ‎3.05, ‎3.06, 8.07 or 10.08
and except for any Contingent Convertible Securities, which, pursuant to ‎Section
3.03, are deemed never to have been authenticated and delivered hereunder);

 

(c) the date or dates, if any, on which
the principal of the Contingent Convertible Securities of the series is payable, including any applicable Stated Maturity, if any,
or Maturity, if any, or whether the Contingent Convertible Securities of the series are perpetual securities with no scheduled
Stated Maturity with respect to the payment of principal of, the Contingent Convertible Securities of the series;

 

(d) whether or not such series of Contingent
Convertible Securities are to be redeemable, in whole or in part, at the Company’s option and, if so redeemable, the period
or periods within which, the price or prices at which and the terms and conditions upon which Contingent Convertible Securities
of the series may be redeemed;

 

(e) the rate or rates, if any, at which
the Contingent Convertible Securities of the series shall accrue interest or the manner of calculation of such rate or rates, if
any, the date or dates from which such interest shall accrue, the Interest Payment Dates on which such interest shall be payable,
if any or the manner of determination of such Interest Payment Dates and the Regular Record Date for the interest payable on any
Interest Payment Date, and any dates required to be established pursuant to ‎Section
7.01;

 

(f) under what conditions, if any, a successor
corporation may be substituted as the issuer of the Contingent Convertible Securities of the series;

 

(g) the terms applicable to deferral or
cancellation of payments of principal or interest, if any, including payments deferred or canceled at the Company’s sole
discretion and whether payments of principal or interest, if any, are subject to any solvency, financial or capital ratio conditions
of the Company or the Group such that the payment of interest is prohibited;

 

(h) provisions, if any, for the discharge
and defeasance of Contingent Convertible Securities of the series;

 

(i) the place or places where the principal
of and any interest on Contingent Convertible Securities of the series shall be payable, and the Paying Agent or Paying Agents
who shall be authorized to pay principal of and interest on Contingent Convertible Securities of such series, at least one of such
Paying Agents having offices or agencies in the Borough of Manhattan, The City of New York;

 

(j) the applicability of ‎Article
10 of this Contingent Convertible Securities Indenture to the Contingent Convertible Securities of such series, and the terms of
any mandatory or optional redemption, repayment or repurchase of the Contingent Convertible Securities of the series (including
for a change in the treatment of the Contingent Convertible Securities for tax or regulatory purposes) and the period or periods
within

 

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which, the terms and conditions upon which
and the price or prices at which the Contingent Convertible Securities of the series may be redeemed, repaid or repurchased, in
whole or in part;

 

(k) if other than denominations of $1,000
and any multiple thereof, the denominations in which Contingent Convertible Securities of the series in each applicable form shall
be issuable and any provisions relating to redenomination of any Contingent Convertible Securities;

 

(l) any conditions on the Company repurchasing
the Contingent Convertible Securities of the series;

 

(m) the terms and conditions, if any, under
which the Company may elect to substitute or vary the terms of the Contingent Convertible Securities of the series;

 

(n) whether the Contingent Convertible Securities
of the series shall be listed on a securities exchange;

 

(o) the inclusion of any Enforcement Events
or other remedies or events permitting remedies that apply with respect to Contingent Convertible Securities of the series together
with any deletions from, limitations or modifications of or additions to any of the provisions as set forth pursuant to ‎Article
5 of this Contingent Convertible Securities Indenture;

 

(p) if other than the full principal amount
thereof, the portion, or the manner of calculation of such portion, of the principal amount of Contingent Convertible Securities
of the series which shall be payable upon redemption of Contingent Convertible Securities of the series that are redeemable before
their Stated Maturity, if any, or which the Trustee shall be entitled to file and prove a claim pursuant to ‎Section
5.03;

 

(q) if additional interest shall not be
payable, or any modifications to the conditions under which additional interest is payable;

 

(r) whether any Additional Notes shall be
issuable;

 

(s) the terms, if any, on which the Contingent
Convertible Securities of the series may or shall be convertible into or exchangeable for Ordinary Shares and whether such conversion
or exchange shall occur following the occurrence of certain trigger events (which may include, but shall not be limited to, certain
regulatory capital events) and if so the terms, if applicable, of the Ordinary Shares into which such Contingent Convertible Securities
are convertible or exchangeable and any additional or other provisions relating to such conversion or exchange, including the terms
upon which such conversion should occur and any specific terms relating to the adjustment thereof and the period during which such
Contingent Convertible Securities may or shall be so converted;

 

(t) if other than Dollars, provisions, if
any, for the Contingent Convertible Securities of the series to be denominated, and payments thereon to be made, in Foreign Currencies
and specifying the Place of Payment and the manner of payment thereon and any other terms with respect thereto;

 

(u) if other than the coin or currency in
which the Contingent Convertible Securities of that series are denominated, the coin or currency in which payment of the principal
of or interest, if any, on the Contingent Convertible Securities of such series shall be payable;

 

(v) if the principal of or interest, if
any, on the Contingent Convertible Securities of such series are to be payable, at the election of the Company or a Holder thereof,
in a coin or currency other than that in which the Contingent Convertible Securities are denominated, the period or periods within
which, and the terms and conditions upon which, such election may be made;

 

(w) the respective rights and obligations,
if any, of the Company and Holders of the Contingent Convertible Securities following a change of control of the Company, including,
if applicable, the terms and conditions under which the Company could be required to redeem or make an offer to purchase Contingent
Convertible Securities of the series;

 

(x) whether the Contingent Convertible Securities
of the series shall be issued, in whole or in part, in the form of one or more Global Securities and the initial Holder with respect
to such Global Security or Contingent Convertible Securities;

 

(y) if the Contingent Convertible Securities
of such series are to be issuable in definitive form (whether upon original issue or upon exchange of a temporary Contingent Convertible
Security of such series or otherwise) only upon receipt of certain certificates or other documents or satisfaction of other conditions,
then the form and terms of such certificates, documents or conditions;

 

(z) if the amounts of payments of principal
of or interest, if any, on the Contingent Convertible Securities of the series may be determined with reference to an index or
are otherwise not fixed on the original issue date thereof, the manner in which such amounts shall be determined and the Calculation
Agent, if any, who shall be appointed and authorized to calculate such amounts;

 

(aa) the ranking and subordination terms
with respect to the Contingent Convertible Securities of the series relative to the debt and equity issued by the Company, including
to what extent the Contingent Convertible Securities of the series may rank junior in right of payment to other of the Company’s
obligations or in any other manner;

 

(bb) the forms of Contingent Convertible
Securities of the series;

 

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(cc) any restrictions applicable to the
offer, sale and delivery of the Contingent Convertible Securities of the series; and

 

(dd) any other terms of the series (which
terms shall not be inconsistent with the provisions of this Contingent Convertible Securities Indenture, except as permitted by
‎Section 8.02(d)).

 

All Contingent Convertible Securities of
the series shall be substantially identical except as to denomination and except as may otherwise be provided in or pursuant to
such action or in any such supplemental indenture.

 

If the forms of Contingent Convertible Securities
of the series, or any of the terms thereof, are established by a shareholders’ meeting or the Board of Directors of the Company,
copies of such shareholders’ resolutions or Board Resolutions in respect thereof shall be delivered to the Trustee at or
prior to the delivery of the Company Order pursuant to ‎Section
3.03 for the authentication and delivery of such Contingent Convertible Securities.

 

Section 3.02. Denominations. The
Contingent Convertible Securities of the series shall be issuable in such denominations as shall be specified as contemplated by
‎Section 3.01. In the absence of any such specification with respect to Contingent Convertible Securities of the series, the
Contingent Convertible Securities of the series shall be issuable in denominations of $1,000 each and any integral multiple thereof.

 

Section 3.03. Execution, Authentication,
Delivery and Dating. The Contingent Convertible Securities shall be executed on behalf of the Company by any Executive Officer.
The signature of any Executive Officer on the Contingent Convertible Securities may be manual or facsimile. Contingent Convertible
Securities bearing the manual or facsimile signatures of individuals who were at any time an Executive Officer of the Company shall
bind the Company, notwithstanding that such individuals or any of them have ceased to hold such offices prior to the authentication
and delivery of such Contingent Convertible Securities.

 

At any time and from time to time after
the execution and delivery of this Contingent Convertible Securities Indenture, the Company may deliver Contingent Convertible
Securities of the series executed by the Company to the Trustee for authentication, together with a Company Order for the authentication
and delivery of such Contingent Convertible Securities, and the Trustee in accordance with the Company Order shall authenticate
and deliver such Contingent Convertible Securities. In authenticating such Contingent Convertible Securities and accepting the
additional responsibilities under this Contingent Convertible Securities Indenture in relation to such Contingent Convertible Securities,
the Trustee shall be entitled to receive, and (subject to ‎Section
6.01) shall be fully protected in relying upon, an Officer’s Certificate and an Opinion of Counsel stating that the form
and terms thereof have been established in conformity with the provisions of this Contingent Convertible Securities Indenture,
that all conditions precedent have been satisfied, and that such Contingent Convertible Securities are legal, valid and binding
obligations of the Company, enforceable against it in accordance with their terms.

 

The Trustee shall not be required to authenticate
such Contingent Convertible Securities if the issue of such Contingent Convertible Securities pursuant to this Contingent Convertible
Securities Indenture shall affect the Trustee’s own rights, duties or immunities under the Contingent Convertible Securities
and this Contingent Convertible Securities Indenture or otherwise in a manner which is not reasonably acceptable to the Trustee.

 

Each Contingent Convertible Security shall
be dated the date of its authentication.

 

No Contingent Convertible Security appertaining
thereto shall be entitled to any benefit under this Contingent Convertible Securities Indenture or be valid or obligatory for any
purpose unless there appears on such Contingent Convertible Security a certificate of authentication substantially in the form
provided for herein executed by or on behalf of the Trustee by manual signature, and such certificate upon any Contingent Convertible
Security shall be conclusive evidence, and the only evidence, that such Contingent Convertible Security has been duly authenticated
and delivered hereunder and that such Contingent Convertible Security is entitled to the benefits of this Contingent Convertible
Securities Indenture. Notwithstanding the foregoing, if any Contingent Convertible Security shall have been authenticated and delivered
hereunder but never issued and sold by the Company, and the Company shall deliver such Contingent Convertible Security to the Trustee
for cancellation as provided in ‎Section 3.09,
for all purposes of this Contingent Convertible Securities Indenture, such Contingent Convertible Security shall be deemed never
to have been authenticated and delivered hereunder and shall never be entitled to the benefit of this Contingent Convertible Securities
Indenture.

 

Section 3.04. Temporary Contingent Convertible
Securities. Pending the preparation of definitive Contingent Convertible Securities of the series, the Company may execute,
and, upon Company Order, the Trustee shall authenticate and deliver, temporary Contingent Convertible Securities substantially
of the tenor of the definitive Contingent Convertible Securities in lieu of which they are issued, which Contingent Convertible
Securities may be printed, lithographed, typewritten, photocopied or otherwise produced. Temporary Contingent Convertible Securities
shall be issuable as registered Contingent Convertible Securities without coupons attached in any authorized denomination, and
with such appropriate insertions, omissions, substitutions and other variations as the officers executing such Contingent Convertible
Securities may determine, all as evidenced by such execution.

 

If temporary Contingent Convertible Securities
of the series are issued, the Company shall cause, if so required by the terms of such temporary Contingent Convertible Securities,
definitive Contingent Convertible Securities of such series to be prepared without unreasonable delay.

 

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After the preparation of definitive Contingent
Convertible Securities of such series, the temporary Contingent Convertible Securities of such series shall be exchangeable for
definitive Contingent Convertible Securities of such series containing identical terms and provisions upon surrender of the temporary
Contingent Convertible Securities of such series at the office or agency of the Company in a Place of Payment for that series,
without charge to the Holder. Upon surrender for cancellation of any one or more temporary Contingent Convertible Securities of
the series, the Company shall execute, and the Trustee shall authenticate and deliver in exchange therefor, a like aggregate principal
amount of definitive Contingent Convertible Securities of the same series of authorized denominations containing identical terms
and provisions. Until so exchanged, unless otherwise provided therein or in a supplemental indenture relating thereto, the temporary
Contingent Convertible Securities of the series shall in all respects be entitled to the same benefits (but shall be subject to
all the limitations of rights) under this Contingent Convertible Securities Indenture as definitive Contingent Convertible Securities
of such series.

 

Section 3.05. Registration, Registration
of Transfer and Exchange.

 

(a) Global Securities. This ‎Section
3.05(a) shall apply to Global Securities unless otherwise specified, as contemplated by ‎Section
3.01.

 

Except as otherwise specified as contemplated
by ‎Section 3.01 hereof, the Contingent Convertible
Securities shall be initially issued and represented by one or more Global Securities in registered form, without coupons attached
thereto, which shall be authenticated as contemplated by this Contingent Convertible Securities Indenture.

 

Each Global Security in registered form
authenticated under this Contingent Convertible Securities Indenture shall be registered in the name of the Depositary designated
for such Global Security or a nominee thereof and delivered to such Depositary or a nominee thereof or custodian therefor, and
each such Global Security shall constitute a single Contingent Convertible Security for all purposes of this Contingent Convertible
Securities Indenture. Except as otherwise specified as contemplated by ‎Section
3.01 hereof, each Global Security in registered form authenticated under this Indenture shall be initially registered in the name
of DTC only.

 

With respect to Global Securities in registered
form, unless the Global Security is presented by an authorized representative of the Holder to the Company or its agent for registration
of transfer, exchange or payment, and any certificate issued is registered in the name of a nominee of the Holder and any payment
is made to such nominee, any transfer, pledge or other use of the Global Security for value or otherwise shall be wrongful since
the registered owner of such Global Security, the nominee of the Holder, has an interest in such Global Security.

 

Except as otherwise specified as contemplated
by ‎Section 3.01 hereof, any Global Security
shall be exchangeable for definitive Contingent Convertible Securities only as provided in this paragraph. A Global Security shall
be exchangeable pursuant to this Section only (i) if the relevant Depositary notifies the Trustee that it is unwilling or unable
to continue to act as Depositary and a successor depositary is not appointed by the Trustee within 120 days of such notification,
(ii) if, in the event of a winding-up of the Company, the Company fails to make a payment on the Contingent Convertible Securities
when due and payable or (iii) at any time if the Company at its option and in its sole discretion determines that the Global Securities
of the series should be exchanged for definitive Contingent Convertible Securities of that series in registered form. Any Global
Security that is exchangeable pursuant to the preceding sentence shall be exchangeable for, unless otherwise specified or contemplated
by ‎Section 3.01, definitive Contingent Convertible
Securities in registered form bearing interest (if any) at the same rate or pursuant to the same formula, having the same date
of issuance, the same date or dates from which such interest shall accrue, the same Interest Payment Dates on which such interest
shall be payable or the manner of determination of such Interest Payment Dates, redemption provisions, if any, specified currency
and other terms and of differing denominations aggregating a like amount as the Global Security so exchangeable. Definitive Contingent
Convertible Securities in registered form shall be registered in the names of the owners of the beneficial interests in such Global
Securities as such names are from time to time provided by the Holder to the Trustee.

 

Any Global Security that is exchangeable
pursuant to the preceding paragraph, unless otherwise specified as contemplated by ‎Section
3.01, shall be exchangeable for Contingent Convertible Securities issuable in authorized denominations of a like aggregate principal
amount and tenor.

 

No Global Security in registered form may
be transferred except as a whole by the Holder to a nominee of the Holder or by the Holder or any such nominee to a successor of
the Holder or a nominee of such successor. Except as provided above, owners solely of beneficial interests in a Global Security
shall not be entitled to receive physical delivery of Contingent Convertible Securities in definitive form and shall not be considered
the holders thereof for any purpose under this Contingent Convertible Securities Indenture.

 

In the event that a Global Security is surrendered
for redemption in part pursuant to ‎Section
10.08, the Company shall execute, and the Trustee shall authenticate and deliver to the Holder of such Global Security, without
service charge, a new Global Security in a denomination equal to and in exchange for the unredeemed or unexchanged portion of the
principal of the Global Security so surrendered.

 

The Agent Members and any other beneficial
owners shall have no rights under this Contingent Convertible Securities Indenture with respect to any Global Security held on
their behalf by a Holder, and such Holder may be treated by the Company, the Trustee, and any agent of the Company or the Trustee
as the owner of such Global Security for all purposes whatsoever. Notwithstanding the foregoing, nothing herein shall (i) prevent
the Company, the Trustee, or any agent of the Company or the Trustee, from giving effect to any written certification, proxy or
other authorization furnished by a Holder or (ii) impair, as between any such Holder or other clearance service and its Agent Members
and Holders, the

 

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operation of customary practices governing
the exercise of the rights of a holder of any security, including without limitation the granting of proxies or other authorization
of participants to give or take any request, demand, authorization, direction, notice, consent, waiver or other action which a
Holder is entitled to give or take under this Contingent Convertible Securities Indenture.

 

In connection with any exchange of interests
in a Global Security for definitive Contingent Convertible Securities of another authorized form, as provided in this ‎Section
3.05(a), then without unnecessary delay but in any event not later than the earliest date on which such interests may be so exchanged,
the Company shall deliver to the Trustee definitive Contingent Convertible Securities in aggregate principal amount equal to the
principal amount of such Global Security or the portion to be exchanged, executed by the Company. On or after the earliest date
on which such interests may be so exchanged, such Global Security shall be surrendered by the Holder to the Trustee, as the Company’s
agent for such purpose, to be exchanged, in whole or from time to time in part, for definitive Contingent Convertible Securities
without charge and the Trustee shall authenticate and deliver, in exchange for each portion of such Global Security, an equal aggregate
principal amount of definitive Contingent Convertible Securities of authorized denominations as the portion of such Global Security
to be exchanged. Any Global Security that is exchangeable pursuant to this ‎Section
3.05 shall be exchangeable for Contingent Convertible Securities issuable in the denominations specified as contemplated by ‎Section
3.01 and registered in such names as the Holder of such Global Security shall direct. If a definitive Contingent Convertible Security
is issued in exchange for any portion of a Global Security after the close of business at the office or agency where such exchange
occurs on any record date and before the opening of business at such office or agency on the relevant Interest Payment Date, interest
shall not be payable on such Interest Payment Date in respect of such definitive Contingent Convertible Security, but shall be
payable on such Interest Payment Date only to the person to whom payments of interest in respect of such portion of such Global
Security are payable.

 

A Depositary may grant proxies and otherwise
authorize any person, including Agent Members and persons that may hold interests through Agent Members, to take any action which
a Holder is entitled to take under this Contingent Convertible Securities Indenture with respect to the Contingent Convertible
Securities.

 

(b) Except as otherwise specified pursuant
to ‎Section 3.01, Contingent Convertible Securities of the series may only be exchanged
for a like aggregate principal amount of registered Contingent Convertible Securities of such series of other authorized denominations
containing identical terms and provisions. Contingent Convertible Securities to be exchanged shall be surrendered at an office
or agency of the Company designated pursuant to ‎Section 9.02 for such purpose,
and the Company shall execute, and the Trustee shall authenticate and deliver, in exchange therefor the Contingent Convertible
Security or Contingent Convertible Securities of the same series which the Holder making the exchange shall be entitled to receive.

 

Except as otherwise specified pursuant to
‎Section 3.01, the Company shall cause to
be kept in the Corporate Trust Office of the Trustee a register (the register maintained in such office and in any other office
or agency of the Company in a Place of Payment being herein sometimes collectively referred to as the “Contingent Convertible
Security Register”) in which, subject to such reasonable regulations as it may prescribe, the Company shall provide for
the registration of registered Contingent Convertible Securities and of transfers of such Contingent Convertible Securities. The
Trustee is hereby appointed “Contingent Convertible Security Registrar” for the purpose of registering Contingent
Convertible Securities in registered form and transfers of Contingent Convertible Securities in registered form as herein provided.

 

Registered Contingent Convertible Securities
shall be transferable only on the Contingent Convertible Security Register. Upon surrender for registration of transfer of any
Contingent Convertible Security of the series, together with the form of transfer endorsed on it, duly completed and executed at
an office or agency of the Company designated pursuant to ‎Section
9.02 for such purpose, the Company shall execute, and the Trustee shall authenticate and deliver to the address specified in the
form of transfer, within three Business Days, in the name of the designated transferee or transferees, one or more new Contingent
Convertible Securities of the same series of any authorized denominations containing identical terms and provisions, of a like
aggregate principal amount. If only part of a Contingent Convertible Security is transferred, a new registered Contingent Convertible
Security of an aggregate principal amount equal to the amount not being transferred shall be executed by the Company, and authenticated
and delivered by the Trustee to the transferor, in the name of the transferor, within three Business Days after the Trustee acting
as Paying Agent pursuant to ‎Section 9.02
received the Contingent Convertible Security. The registered new Contingent Convertible Security shall be delivered to the transferor
by uninsured post at the risk of the transferor to the address of the transferor appearing in the Contingent Convertible Security
Register.

 

All Contingent Convertible Securities issued
upon any registration of transfer or exchange of Contingent Convertible Securities shall be the valid obligations of the Company,
evidencing the same debt, and entitled to the same benefits under this Contingent Convertible Securities Indenture, as the Contingent
Convertible Securities surrendered upon such registration of transfer or exchange.

 

Every registered Contingent Convertible
Security presented or surrendered for registration of transfer or for exchange shall (if so required by the Company or the Trustee)
be duly endorsed, or be accompanied by a written instrument of transfer in form satisfactory to the Company and the Contingent
Convertible Security Registrar duly executed, by the registered Holder thereof or his attorney duly authorized in writing.

 

No service charge shall be made for any
registration of transfer or exchange of Contingent Convertible Securities, but the Company may require payment of a sum sufficient
to cover any tax or other governmental charge that may be imposed in connection with any registration of transfer or exchange of
Contingent Convertible Securities, other than exchanges pursuant to ‎Section
3.04, ‎8.06 or ‎10.08
not involving any transfer.

 

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The Company shall not be required (i) to
issue, register the transfer of or exchange any Contingent Convertible Security of the series during a period beginning at the
opening of business fifteen (15) days before the day of the giving of a notice of redemption of Contingent Convertible Securities
of such series selected for redemption under ‎Section
10.04 and ending at the close of business on the day of the giving of such notice, or (ii) to register the transfer of or exchange
of any Contingent Convertible Security so selected for redemption in whole or in part, except the unredeemed portion of any Contingent
Convertible Securities being redeemed in part.

 

Section 3.06. Mutilated, Destroyed, Lost
and Stolen Contingent Convertible Securities. If any mutilated Contingent Convertible Security (including any Global Security)
is surrendered to the Trustee, the Company may execute and the Trustee shall, in the case of a Contingent Convertible Security,
authenticate and deliver in exchange therefor a new Contingent Convertible Security of the same series containing identical terms
and provisions and of like amount, and bearing a number not contemporaneously outstanding.

 

If there shall be delivered to the Company
and to the Trustee (i) evidence to their satisfaction of the destruction, loss or theft of any Contingent Convertible Security
(including any Global Security) and (ii) such security or indemnity as may be required and deemed sufficient, by them to hold each
of them and any agent of any of them harmless, then, in the absence of notice to the Company or the Trustee that such Contingent
Convertible Security has been acquired by a bona fide purchaser, the Company shall execute and upon its request the Trustee shall
authenticate and deliver in lieu of any such destroyed, lost or stolen Contingent Convertible Security a new Contingent Convertible
Security of the same series containing identical terms and provisions and of like amount, and bearing a number not contemporaneously
outstanding.

 

In case any such mutilated, destroyed, lost
or stolen Contingent Convertible Security has become or is about to become due and payable, the Company in its discretion may,
instead of issuing a new Contingent Convertible Security, pay such Contingent Convertible Security.

 

Upon the issuance of any new Contingent
Convertible Security under this Section, the Company may require the payment of a sum sufficient to cover any tax or other governmental
charge that may be imposed in relation thereto and any other expenses (including the fees and expenses of the Trustee) connected
therewith.

 

Every new Contingent Convertible Security
of the series issued pursuant to this Section in exchange for any mutilated Contingent Convertible Security or in lieu of any destroyed,
lost or stolen Contingent Convertible Security shall constitute an original additional contractual obligation of the Company, whether
or not the mutilated, destroyed, lost or stolen Contingent Convertible Security shall be at any time enforceable by anyone, and
shall be entitled to all the benefits of this Contingent Convertible Securities Indenture equally and proportionately with any
and all other Contingent Convertible Securities of that series duly issued hereunder.

 

The provisions of this Section are exclusive
and shall preclude (to the extent lawful) all other rights and remedies with respect to the replacement or payment of mutilated,
destroyed, lost or stolen Contingent Convertible Securities.

 

Section 3.07. Payment; Interest Rights
Preserved. Except as otherwise provided as contemplated by ‎Section 3.01 with respect to the series of Contingent Convertible
Securities, interest, if any, on any Contingent Convertible Securities which is payable, and is paid or duly provided for, on any
Interest Payment Date shall be paid in the case of registered Contingent Convertible Securities, to the Person in whose name that
Contingent Convertible Security (or one or more Predecessor Securities) is registered at the close of business on the Regular Record
Date for such interest, or in the case of Global Securities held by any Holder, to the Holder (including through a Paying Agent
of the Company designated pursuant to ‎Section 3.01 outside Mexico for collection by the Holder) at the close of business on
the Regular Record Date for such interest.

 

In the case of Contingent Convertible Securities
where payment is to be made in Dollars, payment at any Paying Agent’s office outside The City of New York shall be made in
Dollars by check drawn on, or, at the request of the Holder, by transfer to a Dollar account maintained by the payee with, a bank
in The City of New York. In the case of Contingent Convertible Securities where payment is to be made in a Foreign Currency, payment
shall be made as established pursuant to ‎Section
3.01.

 

The Trustee is hereby appointed as Paying
Agent. The Company shall procure that there will be at all times a Paying Agent. The Company may change the Paying Agent without
prior notice to the Holders and beneficial owners of any Contingent Convertible Securities, and the Company may act as Paying Agent.
The Company may appoint additional or successor agents (each, an “Agent”). The Company may terminate the appointment
of any Agent at any time. In the event of such termination or any Agent being unable or unwilling to continue to act as Agent in
the relevant capacity, the Company shall appoint another bank of international standing as Agent, in the relevant capacity. Any
appointment or termination pursuant to this provision shall be published without undue delay in accordance with the provisions
herein.

 

Subject to the foregoing provisions of this
Section, and except as otherwise provided as contemplated by ‎Section
3.01 with respect to the series of Contingent Convertible Securities, each Contingent Convertible Security delivered under this
Contingent Convertible Securities Indenture upon registration of transfer of or in exchange for or in lieu of any other Contingent
Convertible Security shall carry the rights to interest accrued and unpaid, and to accrue, which were carried by such other Contingent
Convertible Security.

 

Section 3.08. Persons Deemed Owners.
Prior to due presentment of a Contingent Convertible Security for registration of transfer, the Company, the Trustee and any agent
of the Company or the Trustee may treat the Person in whose name such Contingent Convertible Security is

 

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registered as the owner of such Contingent
Convertible Security for the purpose of receiving payment of principal of and (subject to ‎Section 3.05 and ‎Section 3.07)
interest, if any, on such Contingent Convertible Security and for all other purposes whatsoever, whether or not such Contingent
Convertible Security be overdue, and neither the Company, the Trustee nor any agent of the Company or the Trustee shall be affected
by notice to the contrary.

 

Notwithstanding the foregoing, with respect
to any Global Security, nothing herein shall prevent the Company, the Trustee, or any agent of the Company or the Trustee from
giving effect to any written certification, proxy or other authorization furnished by any Depositary (or its nominee), as a Holder,
with respect to such Global Security or shall impair, as between such Depositary and owners of beneficial interests in such Global
Security, the operation of customary practices governing the exercise of the rights of such Depositary (or its nominee) as Holder
of such Global Security.

 

Section 3.09. Cancellation. All Contingent
Convertible Securities surrendered for payment, redemption, registration of transfer or exchange shall, if surrendered to any Person
other than the Trustee, be delivered to the Trustee and shall be promptly canceled by it. The Company may at any time deliver to
the Trustee for cancellation any Contingent Convertible Securities previously authenticated and delivered hereunder and all Contingent
Convertible Securities so delivered shall be promptly canceled by the Trustee. No Contingent Convertible Securities shall be authenticated
in lieu of or in exchange for any Contingent Convertible Securities canceled as provided in this Section, except as expressly permitted
by the provisions of the Contingent Convertible Securities of the series or pursuant to the provisions of this Contingent Convertible
Securities Indenture. The Trustee shall deliver to the Company all canceled Contingent Convertible Securities held by the Trustee.

 

Section 3.10. Computation of Interest.
Except as otherwise specified pursuant to ‎Section 3.01 for Contingent Convertible Securities of the series, payments of interest
on the Contingent Convertible Securities of the series shall be computed on the basis of a 360-day year of twelve 30-day months.

 

Section 3.11. CUSIP Numbers. The
Company in issuing the series of the Contingent Convertible Securities may use “CUSIP”, “ISIN”, “Common
Code” and/or other similar numbers (if then generally in use) or any successor to such numbers and thereafter with respect
to such series, the Trustee shall use “CUSIP”, “ISIN”, “Common Code” and/or other similar numbers
or successor numbers in notices of redemption as a convenience to Holders; provided that any such notice may state that no representation
is made as to the correctness of such numbers either as printed on the Contingent Convertible Securities or as contained in any
notice of a redemption and that reliance may be placed only on the other identification numbers printed on the Contingent Convertible
Securities, and any such redemption shall not be affected by any defect in or omission of such numbers. The Company shall promptly
notify the Trustee of any change in the “CUSIP”, “ISIN”, “Common Code” and/or other similar
numbers or successor numbers.

 

Section 3.12. Additional Contingent Convertible
Securities. Except as otherwise specified pursuant to ‎Section 3.01, the Company may, from time to time, without the consent
of the Holders of the Contingent Convertible Securities of the series, but subject to the approval of Banco de México,
issue additional Contingent Convertible Securities, having the same ranking and same interest rate, Maturity, if any, Stated Maturity,
if any, redemption terms and other terms, except for the price to the public and issue date and first Interest Payment Date, as
such series of Contingent Convertible Securities (the “Additional Notes”). Any such Additional Notes shall rank
equally and ratably with such series of Contingent Convertible Securities in all respects and shall constitute, together with the
previously issued Contingent Convertible Securities of such series, a single series of Contingent Convertible Securities under
this Contingent Convertible Securities Indenture.

 

Section 3.13. Correction of Minor Defects
in or Amendment of Contingent Convertible Securities. If, subject always to ‎Section 8.08, after issuance of any Contingent
Convertible Security (including any Global Security), (i) the Company or the Trustee shall become aware of any ambiguity, defect
or inconsistency in any term of a Contingent Convertible Security or Global Security, as the case may be, or, (ii) with respect
to any Contingent Convertible Security (including any Global Security) issued on or after the date hereof, the Company and the
Trustee agree to amend such Contingent Convertible Security as contemplated by ‎Section 8.02(a), the parties hereto shall provide
for the execution, authentication, delivery and dating of one or more replacement Contingent Convertible Securities or Global Securities,
as the case may be, pursuant to ‎Section 3.03 hereto; provided, however, that such amendment is not materially adverse to Holders
of any Outstanding Contingent Convertible Securities.

 

Section 3.14. General Rules Applicable
to Mexican Banks and Their Application to the Bank. Below is a summary description of the general rules applicable to Mexican
banks and their application to the Bank.

 

(a) Article 121 of the Mexican Banking Law
provides that, in the exercise of its supervisory duties, the CNBV, through general regulations issued thereby, will classify banking
institutions based on their compliance with the provisions of the Mexican Capitalization Requirements, which may take into account
capital ratios that reflect the degree of stability and solvency of a Mexican bank.

 

(b) Article 122 of the Mexican Banking Law
provides that if a Mexican bank does not comply with the capital ratios required to be classified as Class I pursuant to the Mexican
Capitalization Requirements, such bank must implement the corrective measures ordered by the CNBV, which may include

 

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(i) informing the bank’s
board of directors of its classification, based on the capital ratios thereof, and submitting a detailed report containing an evaluation
of the bank’s overall financial status and its level of compliance with applicable regulations; the bank shall provide written
notice to the chief executive officer and the chairman of the board of directors of the bank’s holding company (sociedad
controladora del grupo financiero), which, with regard to the Bank, is the Company, with respect to such events and the status
thereof;

 

(ii) within a period not to exceed
seven (7) calendar days, filing with the CNBV, for its approval, a capital recovery plan to increase the bank’s capital ratios;
the bank’s capital recovery plan shall be approved by such bank’s board of directors before it is submitted to the
CNBV;

 

(iii) suspending any payment of
dividends to its shareholders, as well as any mechanism or act for the making of any distributions or the granting of any economic
benefits to shareholders;

 

(iv) suspending any share repurchase
programs;

 

(v) deferring or canceling payment
of interest and deferring or canceling the payment of principal on outstanding subordinated debt, as the case may be, or, if applicable,
exchanging outstanding convertible subordinated debt into shares of the bank in the amount necessary to cover the capital deficiency
if ordered by the CNBV; these corrective measures shall be applicable to subordinated debt considered part of the bank’s
Tier 1 Capital (capital básico) or Tier 2 Capital (capital complementario); in the event that the bank issues
subordinated debt, the bank is obligated to include in the documentation evidencing such debt, in the applicable indenture and
in the applicable offering document, that such deferral or cancellation of payment of principal or deferral and cancellation of
payments of interest, as the case may be, shall apply upon the occurrence of certain events as provided in the general rules applicable
to Mexican banks and that the implementation of such measures shall not be considered a default under the relevant debt documentation;

 

(vi) suspending payment of any
extraordinary benefits and bonuses that are not a component of the ordinary salary of the chief executive officer or any officer
within the next two levels of seniority, and suspending the granting of new benefits to the chief executive officer and the officers
mentioned above until the bank complies with the minimum capital ratios set forth under the Mexican Capitalization Requirements;

 

(vii) abstaining from increasing
outstanding amounts of any loans granted to any person who is a related party of the bank pursuant to Article 73 and related provisions
of the Mexican Banking Law; and

 

(viii) any other corrective measures
that, in each case, are provided by the general rules applicable to Mexican banks.

 

(c) Article 122 of the Mexican Banking Law
further provides that

 

(i) If a Mexican bank complies
with the minimum capital ratios required pursuant to the Mexican Capitalization Requirements but any of its capital ratios is below
the capital ratios required to be satisfied for a bank not to be subject to any corrective measures, such bank must implement certain
corrective measures ordered by the CNBV, including, among others, (A) informing the bank’s board of directors of its classification,
based on the capital ratios thereof and submitting a detailed report containing an evaluation of the bank’s overall financial
status and its level of compliance with applicable regulations, including the principal regulatory ratios, that reflect the bank’s
degree of stability and solvency (together with any determinations or indications made by any of the CNBV or Banco de México)
and providing written notice to the chief executive officer and the chairman of the board of directors of the bank’s holding
company (sociedad controladora del grupo financiero), which, with regard to the Bank, is the Company, with respect to such
events and the status thereof; (B) abstaining from entering into any transaction that may decrease the bank’s capital ratios
below the Mexican Capitalization Requirements; and (C) any other corrective measures ordered by the CNBV.

 

(ii) Regardless of the capitalization
level, the CNBV may order the implementation of additional special corrective measures applicable to Mexican banks, including,
among others, (1) requiring compliance with additional corrective measures that the bank will be required to carry out to avoid
a decrease of its capital ratios; (2) special audits to be performed by special auditors in connection with specific matters; (3)
abstaining from increasing the salaries and benefits of all officers and employees of the bank, except for any change in salary
previously agreed on and subject to the officers’ and employees’ labor rights; (4) removing officers, directors, statutory
auditors or external auditors or appointing any persons to such positions; or (5) any other measures ordered by the CNBV, based
on its inspection and supervision authorities or sound banking practices.

 

(iii) If a Mexican bank does not
comply with any Capital Supplement requirements pursuant to the Mexican Banking Law and the Mexican Capitalization Requirements,
the CNBV may order the bank to suspend any payment of dividends or other distributions to its shareholders.

 

(iv) Corrective measures will
not be applicable to Mexican banks with a capital ratio equal to or greater than the capital ratios required to be classified as
Class I pursuant to the Mexican Capitalization Requirements.

 

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(d) The Mexican Banking Law and the general
rules applicable to Mexican banks classify Mexican banks in categories from I through V based on their capital ratios for Total
Net Capital (capital neto), Tier 1 Capital (capital básico) and Fundamental Capital (capital fundamental);
corrective measures are imposed based on such classification, starting at the time a bank is included in the category Class II.

 

(e) Article 122 of the Mexican Banking Law
specifies that if a bank does not satisfy the capital ratios required to be classified as Class I pursuant to the Mexican Capitalization
Requirements, the bank must implement the corrective measures ordered by the CNBV. Currently, the minimum capital ratios required
to be classified as Class I are (i) 10.5% in the case of the Total Net Capital (capital neto), (ii) 8.5% in the case of
Tier 1 Capital (capital básico) and (iii) 7.0% in the case of Fundamental Capital (capital fundamental), plus,
in each case, any applicable Capital Supplement.

 

(f) Further, according to the general rules
applicable to Mexican banks in effect on the date hereof, a Mexican bank is classified as Class II, III, IV or V, if any of its
capital ratios is below certain minimum capital ratios, which as of the date of this Contingent Convertible Securities Indenture
are, (i) 10.5% in the case of Total Net Capital (capital neto), (ii) 8.5% in the case of Tier 1 Capital (capital básico),
or (iii) 7.0% in the case of Fundamental Capital (capital fundamental), plus, in each case, any applicable Capital Supplement
thereof required under the Mexican Capitalization Requirements.

 

(g) The general rules applicable to Mexican
banks further provide that corrective measures applicable to Mexican banks classified as Class II, III, IV or V include, among
others, requiring a bank to suspend or cancel payment of interest and defer or cancel payment of any principal on outstanding subordinated
debt or exchange outstanding convertible subordinated debt into shares of the bank in the amount necessary to cover the capital
deficiency; in the event that a bank issues subordinated debt, a bank must include in the relevant debt documentation, in the applicable
indenture and in the applicable offering document, that such suspension or cancellation of payment of interest and deferral or
cancellation of payment of principal shall apply to subordinated debt in the event that a bank is classified as Class II, III,
IV or V and that the implementation of such measures shall not be considered a default under the relevant debt documentation.

 

(h) Mexican banks that are determined by
the CNBV to be D-SIBs, in light of the impact that their default may cause to the Mexican financial system, the Mexican payment
system or the Mexican economy, are required by the CNBV to implement an additional Systemically Important Bank Capital Supplement.
The CNBV also has the authority to require a Countercyclical Capital Supplement on any and all Mexican banks, designed to cover
adverse economic cycles, in the event that the aggregate financing received by the Mexican private sector grows at a higher level
as compared to the level of growth of the Mexican economy.

 

Section 3.15. Restrictions Applicable
to the Bank and to Other Mexican Financial Institutions. Unless otherwise permitted by applicable Mexican law, the Contingent
Convertible Securities (i) may not constitute collateral granted in favor of Mexican credit institutions (instituciones de crédito),
including the Bank, and (ii) may not be directly or indirectly acquired by the Bank for its own account or by any person controlled
by the Bank, or by any of the following entities

 

(a) Mexican financial entities (entidades
financieras) of any kind that acquire the Contingent Convertible Securities for their own accounts, except for (i) investment
companies that invest in debt and variable yield instruments (fondos de inversión en instrumentos de deuda y de renta
variable), (ii) securities brokers (casas de bolsa) that acquire the Contingent Convertible Securities for placement
with investors and (iii) insurance companies (instituciones y sociedades mutualistas de seguros) and bonding companies (instituciones
de fianzas) to the extent they acquire the Contingent Convertible Securities to invest their technical reserves; provided,
however, that the exceptions referred to in (i), (ii) and (iii) of this paragraph shall not apply to (x) investment companies in
which the Bank or any other entity that forms part of the Bank’s financial group (grupo financiero) holds, directly
or indirectly, the majority of its fixed capital and (y) financial entities that form part of the Bank’s financial group
(grupo financiero), of which the Company is the holding company (sociedad controladora del grupo financiero);

 

(b) Mexican or non-Mexican entities with
respect to which the Bank (i) owns voting stock representing at least 51% of their outstanding paid-in capital, (ii) has control
of the shareholders’ meetings of such entity, as such term is defined in the Mexican Securities Market Law, or (iii) is in
a position to appoint the majority of the members of such entity’s board of directors;

 

(c) Mexican pension or retirement funds
if managed by the Bank or another entity that forms part of the Bank’s financial group (grupo financiero), of which
the Company is the holding company (sociedad controladora del grupo financiero); an

 

(d) the Bank or another entity that forms
part of its financial group (grupo financiero), of which the Company is the holding company (sociedad controladora del
grupo financiero), acting in its capacity of trustee, representative, agent or attorney-in-fact if, by acting in such capacity,
it has discretionary investment authority; provided, however, that any Mexican financial entity or Mexican pension or retirement
fund that is not otherwise prevented from investing in the Contingent Convertible Securities may acquire, together with any other
such entity that is an affiliate or that forms part of the same financial group on a collective basis, up to 10% of the aggregate
principal amount of the outstanding Contingent Convertible Securities.

 

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Article
4

Satisfaction and Discharge

 

Section 4.01. Satisfaction and Discharge
of Contingent Convertible Securities Indenture. This Contingent Convertible Securities Indenture shall upon Company Request
cease to be of further effect with respect to Contingent Convertible Securities of the series (except as to any surviving rights
of registration of transfer or exchange of Contingent Convertible Securities of such series herein expressly provided for), and
the Trustee, at the direction and expense of the Company, shall execute proper instruments acknowledging satisfaction and discharge
of this Contingent Convertible Securities Indenture with respect to the Contingent Convertible Securities of such series when

 

(a) either

 

(i) all Contingent Convertible
Securities of such series theretofore authenticated and delivered (other than (A) Contingent Convertible Securities that have been
destroyed, lost or stolen and that have been replaced or paid as provided in ‎Section 3.06 and (B) Contingent Convertible
Securities for whose payment money has theretofore been deposited in trust or segregated and held in trust by the Company and thereafter
repaid to the Company or discharged from such trust, as provided in ‎Section 9.03) have been delivered to the Trustee for cancellation;
or

 

(ii) all such Contingent Convertible
Securities not theretofore delivered to the Trustee for cancellation

 

(A) have become due and payable
or will become due and payable at their Stated Maturity, if any, within one year, or

 

(B) are to be called for redemption
within one year under arrangements satisfactory to the Trustee for the giving of notice of redemption by the Trustee in the name,
and at the expense, of the Company,

 

and (1) the Company has deposited or caused to be
deposited with the Trustee, as trust funds in trust for the purpose, an amount in cash, or U.S. Government Obligations (with respect
to Contingent Convertible Securities denominated in Dollars) or Foreign Government Securities (with respect to Contingent Convertible
Securities denominated in the same Foreign Currency) maturing, in the case of (A) and (B) above, as to principal and interest,
if any, in such amounts and at such times as will ensure the availability of cash sufficient to pay, satisfy and discharge all
claims with respect to such Contingent Convertible Securities not theretofore delivered to the Trustee for cancellation, in the
case of (A) and (B) above, for principal and accrued interest, if any, to the date of such deposit (in the case of Contingent Convertible
Securities which have become due and payable) or to the Redemption Date; and (2) no Enforcement Event and no event which, after
notice or lapse of time or both, would become an Enforcement Event shall have occurred and be continuing;

 

(b) the Company has paid or caused to be
paid all other sums payable hereunder (including any accrued but unpaid interest) by the Company with respect to the Contingent
Convertible Securities of such series and no Enforcement Event and no event which, after notice or lapse of time or both, would
become an Enforcement Event shall have occurred and be continuing; and

 

(c) the Company has delivered to the Trustee
an Officer’s Certificate and an Opinion of Counsel, each stating that all conditions precedent herein provided for relating
to the satisfaction and discharge of this Contingent Convertible Securities Indenture with respect to the Contingent Convertible
Securities of such series have been complied with.

 

Notwithstanding any satisfaction and discharge
of this Contingent Convertible Securities Indenture, the obligations of the Company to the Trustee under ‎Section
6.05, the obligations of the Company to any Authenticating Agent under ‎Section
6.15 and, if cash, U.S. Government Obligations and/or Foreign Government Securities shall have been deposited with the Trustee
pursuant to ‎Section 4.01(a)(ii), the obligations
of the Trustee under ‎Section 4.02 and the
last paragraph of ‎Section 9.03 shall survive
such satisfaction and discharge, including any termination under bankruptcy law.

 

Section 4.02. Application of Trust Money.
Subject to the provisions of the last paragraph of ‎Section 9.03, all cash, U.S. Government Obligations and Foreign Government
Securities deposited with the Trustee pursuant to ‎Section 4.01 shall be held in trust and such cash and the proceeds from
such U.S. Government Obligations and/or Foreign Government Securities shall be applied by it, in accordance with the provisions
of the Contingent Convertible Securities of such series, and this Contingent Convertible Securities Indenture, to the payment,
either directly or through any Paying Agent (including the Company acting as Paying Agent) as the Trustee may determine, to the
Persons entitled thereto, of the principal and interest for the payment of which such cash, U.S. Government Obligations and/or
Foreign Government Securities have been deposited with the Trustee.

 

Section 4.03. Repayment to Company.
The Trustee, the Calculation Agent and any Paying Agent promptly shall pay to the Company any excess money, U.S. Government Obligations
and/or Foreign Government Securities held by them at any time with respect to the series of Contingent Convertible Securities.

 

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Article
5

Remedies

 

Section 5.01. Enforcement Events.
“Enforcement Event”, wherever used herein with respect to Contingent Convertible Securities of the series, means
any Enforcement Event or such other remedies identified as Enforcement Events for purposes of this ‎Article 5 provided with
respect to Contingent Convertible Securities of the series pursuant to ‎Section 3.01.

 

Section 5.02. Collection of Indebtedness
and Suits for Enforcement by Trustee. No recourse for the payment of the principal of or interest, if any, on any Contingent
Convertible Security, or for any claim based thereon or otherwise in respect thereof, and no recourse under or upon any obligation,
covenant or agreement of the Company in this Contingent Convertible Securities Indenture, or in any Contingent Convertible Security,
or because of the creation of any indebtedness represented thereby, shall be had against any incorporator, stockholder, officer
or director, past, present or future, of the Company or of any successor corporation of the Company, either directly or through
the Company or any successor corporation, whether by virtue of any constitution, statute or rule of law, or by the enforcement
of any assessment or penalty or otherwise; it being expressly understood that, to the extent lawful, all such liability is hereby
expressly waived and released as a condition of, and as a consideration for, the execution of this Contingent Convertible Securities
Indenture and the issue of the Contingent Convertible Securities.

 

Section 5.03. Trustee May File Proofs
of Claim. In case of the pendency of any receivership, insolvency, administration, liquidation, bankruptcy, reorganization,
arrangement, adjustment, composition, winding-up or other similar judicial proceeding relative to the Company or any other obligor
upon the Contingent Convertible Securities of the series or to the property of the Company or such obligor or their creditors (other
than under or in connection with a scheme of amalgamation or reconstruction not involving bankruptcy or insolvency), the Trustee
(irrespective of whether the principal of the Contingent Convertible Securities of such series shall then be due and payable as
therein expressed or by declaration or otherwise and irrespective of whether the Trustee shall have made any demand on the Company
for the payment of overdue principal or interest, if any) shall be entitled and empowered, by intervention in such proceeding or
otherwise, to take any and all actions authorized under the Trust Indenture Act in order to have claims of the Holders and the
Trustee allowed in any such proceeding. In particular, and subject as aforesaid, the Trustee shall be authorized to collect and
receive any moneys and other property payable or deliverable on any such claims and to distribute the same; and any custodian,
receiver, assignee, trustee, liquidator, sequestrator or other similar official in any such judicial proceeding is hereby authorized
by each Holder of a Contingent Convertible Security to make such payments to the Trustee and, in the event that the Trustee shall
consent to the making of such payments directly to such Holders or holders, to first pay to the Trustee any amount due to it for
the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel, and any other amounts
due to the Trustee under ‎Section 6.07.

 

Subject to ‎Article
7 and ‎Section 8.03, nothing herein contained
shall be deemed to authorize the Trustee to authorize or consent to or accept or adopt on behalf of any Holder of any Contingent
Convertible Security any plan of reorganization, arrangement, adjustment or composition affecting any Contingent Convertible Securities
or the rights of any Holder of any Contingent Convertible Security or to authorize the Trustee to vote in respect of the claim
of any such Holder or holder in any such proceeding.

 

The provisions of this ‎Section
5.03 with respect to amounts owed on the Contingent Convertible Securities are subject to the provisions of ‎Article
11.

 

Section 5.04. Trustee May Enforce Claims
without Possession of Contingent Convertible Securities. All rights of action and claims under this Contingent Convertible
Securities Indenture or the Contingent Convertible Securities may be prosecuted and enforced by the Trustee without the possession
of any of the Contingent Convertible Securities or the production thereof in any proceeding relating thereto, and any such proceeding
instituted by the Trustee shall be brought in its own name as trustee of an express trust, and any recovery of judgment shall,
after provision for the payment of the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents
and counsel (subject, with regard to the Company, to the provisions of ‎Article 11) be for the ratable benefit of the Holders
of the Contingent Convertible Securities in respect of which such judgment has been recovered.

 

Section 5.05. Application of Money Collected.
Any money collected by the Trustee pursuant to this Article or, after an Enforcement Event, any money or other property distributable
in respect of the Company’s obligations under this Contingent Convertible Securities Indenture, in respect of the series
of Contingent Convertible Securities shall, subject to the provisions of ‎Section 5.02 in relation to waiver and set-off and
‎Article 11 in relation to subordination insofar as they apply to the claims of the Holders, be applied in the following order,
at the date or dates fixed by the Trustee and, in case of the distribution of such money on account of principal or interest, if
any, upon presentation of such Contingent Convertible Securities and the notation thereon of the payment if only partially paid
and upon surrender thereof if fully paid:

 

FIRST: To the payment of all amounts applicable
to such series of Contingent Convertible Securities in respect of which or for the benefit of which such money has been collected
and is due and owing to the Trustee (including any predecessor Trustee) under ‎Section
6.07;

 

SECOND: Subject to ‎Section
11.01, to the payment of the amounts then due and unpaid for principal of and interest, if any, on such series of Contingent Convertible
Securities in respect of which or for the benefit of which such money has been collected, ratably, without preference or priority
of any kind, according to the amounts due and payable on such Contingent Convertible Securities for principal and interest, if
any, respectively; and

 

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THIRD: To the payment of the balance, if
any, to the Company or any other Person or Persons legally entitled thereto.

 

Section 5.06. Limitation on Suits.
Except as otherwise provided by ‎Section 3.01 in respect of the series of Contingent Convertible Securities, no Holder of any
Contingent Convertible Security of the series shall have any right to institute any proceeding, judicial or otherwise, with respect
to this Contingent Convertible Securities Indenture, or for the appointment of a receiver or trustee, or for any other remedy hereunder,
unless

 

(a) such Holder has previously given written
notice to the Trustee of a continuing Enforcement Event with respect to Contingent Convertible Securities of the same series specifying
such Enforcement Event and stating that such notice is a “Notice of Enforcement Event” hereunder;

 

(b) the Holders of not less than 25% in
aggregate principal amount of the Outstanding Contingent Convertible Securities of such series shall have made written request
to the Trustee to institute proceedings in accordance with ‎Section 5.02 to ‎5.04
hereof in respect of such Enforcement Event in its own name, as Trustee hereunder;

 

(c) such Holder of a Contingent Convertible
Security has offered to the Trustee reasonable indemnity satisfactory to it against the costs, expenses and liabilities to be incurred
in compliance with such request;

 

(d) the Trustee for sixty (60) days after
its receipt of such notice, request and offer of indemnity has failed to institute proceedings with the provisions of this Contingent
Convertible Securities Indenture and any supplemental indenture; and

 

(e) no direction inconsistent with such
written request has been given to the Trustee during such 60-day period by the Holders of a majority in principal amount of the
Outstanding Contingent Convertible Securities of such series,

 

it being understood and intended that no one or more Holders
of Contingent Convertible Securities of the series shall have any right in any manner whatever by virtue of, or by availing of,
any provision of this Contingent Convertible Securities Indenture to affect, disturb or prejudice the rights of any other such
Holders or holders, or to obtain or to seek to obtain priority or preference over any other such Holders or holders or to enforce
any right under this Contingent Convertible Securities Indenture, except in the manner herein provided and for the equal and ratable
benefit of all Holders of Contingent Convertible Securities of such series.

 

Section 5.07. Unconditional Right of
Holders to Receive Principal and Interest, if any. Subject to ‎Article 11 in relation to subordination and except as otherwise
provided by any supplemental indenture with respect to the series of Contingent Convertible Securities, notwithstanding any other
provision in this Contingent Convertible Securities Indenture, the Holder of any Contingent Convertible Security shall have the
right, which is absolute and unconditional, to receive payment of the principal of and interest, if any, on such Contingent Convertible
Security when due and payable as expressed in such Contingent Convertible Security (including upon an Enforcement Event, if any,
or on any Stated Maturity or Redemption Date, as the case may be), and to institute suit for the enforcement of any such payment,
and such rights shall not be impaired without the consent of such Holder or holder.

 

Section 5.08. Restoration of Rights and
Remedies. If the Trustee or any Holder of any Contingent Convertible Security has instituted any proceeding to enforce any
right or remedy under this Contingent Convertible Securities Indenture and such proceeding has been discontinued or abandoned for
any reason, or has been determined adversely to the Trustee or to such Holder, then and in every such case, subject to any determination
in such proceeding, the Company, the Trustee and the Holders of Contingent Convertible Securities shall be restored severally and
respectively to their former positions hereunder, and thereafter all rights and remedies of the Trustee and the Holders of Contingent
Convertible Securities shall continue as though no such proceeding had been instituted.

 

Section 5.09. Rights and Remedies Cumulative.
Except as otherwise provided with respect to the replacement or payment of mutilated, destroyed, lost or stolen Contingent Convertible
Securities in the last paragraph of ‎Section 3.06 and without prejudice to ‎Section 5.02, no right or remedy herein conferred
upon or reserved to the Trustee or to the Holders of Contingent Convertible Securities is intended to be exclusive of any other
right or remedy, and every right and remedy shall, to the extent permitted by law, be cumulative and in addition to every other
right and remedy given hereunder or now or hereafter existing at law or in equity or otherwise. The assertion or employment of
any right or remedy hereunder, or otherwise, shall not, subject as aforesaid, prevent the concurrent assertion or employment of
any other appropriate right or remedy.

 

Section 5.10. Delay or Omission Not Waiver.
No delay or omission of the Trustee or of any Holder of any Contingent Convertible Security to exercise any right or remedy accruing
upon any Enforcement Event shall impair any such right or remedy or constitute a waiver of any such Enforcement Event or an acquiescence
therein. Every right and remedy given by this Article or by law to the Trustee or to the Holders of Contingent Convertible Securities
may be exercised from time to time, and as often as may be deemed expedient, by the Trustee or by the Holders of Contingent Convertible
Securities, as the case may be.

 

Section 5.11. Control by Holders.
Except as otherwise specified pursuant to ‎Section 3.01 in respect of the series of Contingent Convertible Securities, the
Holders of a majority in aggregate principal amount of the Outstanding Contingent Convertible Securities of the series shall have
the right to direct the time, method and place of conducting any proceeding in name of or on behalf of the Trustee for any remedy
available to the

 

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Trustee hereunder, or exercising any trust
or power conferred on the Trustee hereunder with respect to the Contingent Convertible Securities of such series; provided that
such direction is in writing and the Trustee has been offered indemnity and/or security satisfactory to it in its sole discretion
and

 

(a) such direction shall not be in conflict
with any rule of law or with this Contingent Convertible Securities Indenture or any supplemental indenture hereto;

 

(b) the Trustee shall not determine that
the action so directed would be unjustly prejudicial to the Holders of any Contingent Convertible Securities of the series not
taking part in such direction with respect to which the Trustee is acting as the Trustee; and

 

(c) the Trustee may take any other action
deemed proper by the Trustee that is not inconsistent with such direction.

 

Section 5.12. Undertaking for Costs.
All parties to this Contingent Convertible Securities Indenture agree, and each Holder of any Contingent Convertible Security by
his acceptance thereof shall be deemed to have agreed, that any court may in its discretion require, in any suit for the enforcement
of any right or remedy under this Contingent Convertible Securities Indenture, or in any suit against the Trustee for any action
taken, suffered or omitted by it as Trustee, the filing by any party litigant to such suit of an undertaking to pay the costs of
such suit, and that such court may in its discretion assess reasonable costs, including reasonable attorneys’ fees and expenses,
against any party litigant in such suit, having due regard to the merits and good faith of the claims or defenses made by such
party litigant; but the provisions of this Section shall not apply to any suit instituted by the Trustee, to any suit instituted
by any Holder or group of Holders holding in the aggregate more than 10% in principal amount of the Outstanding Contingent Convertible
Securities of the series, or to any suit instituted by any Holder for the enforcement of the payment of the principal of or interest,
if any, on any Contingent Convertible Security on or after any respective Stated Maturities expressed in such Contingent Convertible
Security (or, in the case of redemption, on or after the Redemption Date).

 

Article
6

The Trustee

 

Section 6.01. Duties of Trustee.

 

(a) (i) The Trustee undertakes to perform
such duties and only such duties as are specifically set forth in this Contingent Convertible Securities Indenture, and no implied
covenants or obligations shall be read into this Contingent Convertible Securities Indenture against the Trustee; and (ii) in the
absence of bad faith on its part, the Trustee may conclusively rely, as to the truth of the statements and the correctness of the
opinions expressed therein, upon any certificates or opinions furnished to the Trustee and conforming to the requirements of this
Contingent Convertible Securities Indenture. However, in the case of any such certificates or opinions which by any provisions
hereof are specifically required to be furnished to the Trustee, the Trustee shall examine such certificates and opinions to determine
whether or not they conform to the requirements of this Contingent Convertible Securities Indenture (but need not confirm or investigate
the accuracy of mathematical calculations or other facts, statements, opinions or conclusions stated therein).

 

(b) The Trustee may not be relieved from
liability for its own negligent action, its own negligent failure to act or its own willful misconduct, except that

 

(i) this paragraph (b) does not
limit the effect of paragraph (a) of this ‎Section 6.01;

 

(ii) the Trustee shall not be
liable for any error of judgment made in good faith by a Trust Officer unless it is proved that the Trustee was negligent in ascertaining
the pertinent facts; and

 

(iii) the Trustee shall not be
liable with respect to any action it takes or omits to take in good faith in accordance with a direction received by it pursuant
to ‎Section 5.11.

 

(c) The Trustee shall not be liable for
interest on any money received by it except as the Trustee may agree in writing with the Company.

 

(d) Money held in trust by the Trustee need
not be segregated from other funds except to the extent required by law.

 

(e) No provision of this Contingent Convertible
Securities Indenture shall require the Trustee to expend or risk its own funds or otherwise incur financial liability in the performance
of any of its duties hereunder or in the exercise of any of its rights or powers.

 

(f) Unless otherwise provided herein, every
provision of this Contingent Convertible Securities Indenture relating to the conduct or affecting the liability of or affording
protection to the Trustee shall be subject to the provisions of this ‎Article 6.

 

(g) Unless otherwise specifically provided
in this Contingent Convertible Securities Indenture, any demand, request, direction or notice from the Company shall be sufficient
if signed by an Executive Officer.

 

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(h) If an Enforcement Event has occurred
and is continuing, the Trustee shall be under no obligation to exercise any of the rights or powers vested in it by this Contingent
Convertible Securities Indenture at the request or direction of any of the Holders unless such Holders shall have offered to the
Trustee security or indemnity satisfactory to it against the costs, expenses (including reasonable attorneys’ fees and expenses)
and liabilities that might be incurred by it in compliance with such request or direction.

 

(i) The permissive right of the Trustee
to take or refrain from taking action hereunder shall not be construed as a duty.

 

Section 6.02. Rights of Trustee. Subject
to ‎Section 6.01,

 

(a) The Trustee may conclusively rely and
shall be fully protected in acting or refraining from acting upon any resolution, certificate, statement, instrument, opinion,
report, notice, request, direction, consent, order, bond, debenture, note, other evidence of indebtedness or other paper or document
believed by it in good faith to be genuine and to have been signed or presented by the proper Person. The Trustee need not investigate
any fact or matter stated in the document.

 

(b) Before the Trustee acts or refrains
from acting at the direction of the Company, it may require an Officer’s Certificate or an Opinion of Counsel. The Trustee
shall not be liable for any action it takes or omits to take in good faith in reliance on an Officer’s Certificate or an
Opinion of Counsel.

 

(c) The Trustee may act and rely and shall
be protected in acting and relying in good faith on the opinion or advice of, or information obtained from, any counsel, accountant,
appraiser or other expert or adviser, whether retained or employed by the Company or by the Trustee, in relation to any matter
arising in the administration of the trusts hereof.

 

(d) The Trustee shall not be liable for
any action it takes, suffers or omits to take in good faith which it believes to be authorized or within its discretion, rights
or powers; provided, however, that the Trustee’s conduct does not constitute willful misconduct or negligence.

 

(e) The Trustee may consult with counsel
of its selection, and the advice or any Opinion of Counsel with respect to legal matters relating to this Contingent Convertible
Securities Indenture and the Contingent Convertible Securities shall be full and complete authorization and protection from liability
in respect to any action taken, omitted or suffered by it hereunder in good faith and in accordance with the advice or opinion
of such counsel.

 

(f) If the Trustee shall so determine, it
shall be entitled to examine the books, records and premises of the Company, personally or by agent or attorney, during reasonable
business hours and upon reasonable notice.

 

(g) The Trustee shall not be deemed to have
actual or constructive knowledge or notice of a default or Enforcement Event unless written notice of any event which is in fact
such an Enforcement Event is received by a Trust Officer of the Trustee at the Corporate Trust Office of the Trustee, and such
notice references the Contingent Convertible Securities and this Contingent Convertible Securities Indenture.

 

(h) The rights, privileges, protections,
immunities and benefits given to the Trustee, including, without limitation, its right to be indemnified, are extended to, and
shall be enforceable by, the Trustee in each of its capacities hereunder as Transfer Agent, Registrar and Paying Agent, and to
each agent, custodian and other Person employed to act hereunder.

 

(i) Subject to ‎Section
6.01, in no event shall the Trustee be responsible or liable under or in connection with this Contingent Convertible Securities
Indenture for special, indirect, punitive or consequential loss or damage of any kind whatsoever (including, but not limited to,
loss of profit) irrespective of whether the Trustee has been advised of the likelihood of such loss or damage and regardless of
the form of action.

 

(j) The Trustee may request that the Company
deliver a certificate setting forth the names of individuals and titles and direct dial telephone numbers of officers authorized
at such time to take specified actions pursuant to this Contingent Convertible Securities Indenture, which certificate may be signed
by any person authorized to sign an Officer’s Certificate, including any person specified as so authorized in any such certificate
previously delivered and not superseded.

 

(k) The Trustee shall not be bound to make
any investigation into the facts or matters stated in any resolution, certificate, statement, instrument, opinion, report, notice,
request, direction, consent, order, bond, debenture, note, other evidence of indebtedness or other paper or document, but the Trustee,
in its discretion, may make such further inquiry or investigation into such facts or matters as it may see fit at the reasonable
expense of the Company.

 

(l) The Trustee may execute its powers or
perform any of its duties hereunder either directly or by or through agents or attorneys and the Trustee shall not be responsible
for any misconduct or negligence on the part of any such agent or attorney appointed with due care by it hereunder.

 

(m) Each of the Company and each Holder
by purchasing its Contingent Convertible Security agrees to provide upon a request from the Trustee any information that is reasonably
available to it and is necessary to determine whether any tax or withholding obligations apply; provided that no Holder shall be
required to provide any materially more onerous information than would be required to be provided had such Holder been

 

    24

     

    

required to file Internal Revenue Service
Forms W-8BEN, W-8BEN-E, W-8ECI, W-8EXP and/or W-8IMY, except to the extent required under applicable law or regulation or a double
taxation treaty to which Mexico or any other jurisdiction through which payments are made or any authority or agency therein having
power to tax is a party and which is in effect, so that the Company may determine the appropriate rate for tax withholding. The
Trustee shall be entitled to withhold from any payment if required by law to do so to comply with such obligations and shall have
no liability in connection therewith.

 

(n) the Trustee shall not be liable for
any failure or delay in the performance of its obligations hereunder because of circumstances beyond its control, including, but
not limited to, acts of God, flood, war (whether declared or undeclared), terrorism, strikes, work stoppages, civil or military
disturbances, nuclear or natural catastrophes, fire, riot, embargo, loss or malfunctions of utilities, communications or computer
(software and hardware) services, government action, including any laws, ordinances, regulations, governmental action or the like
which delay, restrict or prohibit the providing of the services contemplated by this Contingent Convertible Securities Indenture.

 

Section 6.03. Trustee’s Disclaimer.

 

(a) The Trustee shall not be liable for
any action taken, suffered, or omitted to be taken by it in good faith and believed by it to be authorized or within its rights
or powers conferred upon it. The Trustee shall not be responsible for and makes no representation as to the validity or adequacy
of this Contingent Convertible Securities Indenture or the Contingent Convertible Securities, it shall not be accountable for the
Company’s use of the proceeds from the issuance of the series of Contingent Convertible Securities, and it shall not be responsible
for any statement of the Company in this Contingent Convertible Securities Indenture or in any document issued in connection with
the sale of the series of Contingent Convertible Securities or in the Contingent Convertible Securities other than the Trustee’s
certificate of authentication.

 

Section 6.04. Notice of Enforcement Events.
If an Enforcement Event occurs and is continuing and if a Trust Officer has actual knowledge thereof, the Trustee shall mail
to each Holder notice of the Enforcement Event within 90 days after the occurrence thereof.

 

Section 6.05. May Hold Contingent Convertible
Securities. The Trustee, any Authenticating Agent, any Paying Agent, any Contingent Convertible Security Registrar and any
Calculation Agent or any other agent of the Company, in its individual or any other capacity, may become the owner or pledgee of
Contingent Convertible Securities and, subject to ‎Section 6.10 and ‎Section 6.15, may otherwise deal with the Company
with the same rights it would have if it were not Trustee, Authenticating Agent, Paying Agent, Contingent Convertible Security
Registrar, Calculation Agent or such other agent.

 

Section 6.06. Money Held in Trust.
Money held by the Trustee in trust hereunder need not be segregated from other funds except to the extent required by law. The
Trustee shall be under no liability for interest on any money received by it hereunder except as otherwise agreed in writing with
the Company.

 

Section 6.07. Compensation and Indemnity.

 

(a) The Company shall pay to the Trustee
from time to time reasonable compensation for its acceptance of this Contingent Convertible Securities Indenture and services hereunder
as the Company and the Trustee shall from time to time agree in writing. The Trustee’s compensation shall not be limited
by any law on compensation of a trustee of an express trust. The Company shall reimburse the Trustee upon request for all reasonable
and duly documented or invoiced out-of-pocket fees and expenses incurred or made by it arising out of or in connection with its
duties hereunder, including, without limitation, costs of collection, costs of preparing and reviewing reports, certificates and
other documents, costs of preparation and mailing of notices to Holders and reasonable and duly documented costs of counsel retained
by the Trustee in connection with the delivery of an Opinion of Counsel or otherwise, in addition to the compensation for its services.
Such expenses shall include the reasonable and duly documented compensation and expenses, disbursements and advances of the Trustee’s
agents, counsel, accountants and experts.

 

(b) The Company shall indemnify the Trustee
and its officers, agents, directors and employees against any and all loss, liability, damages, claims or expenses, including taxes,
other than taxes based upon, measured by or determined by the income of the Trustee, (including reasonable and duly documented
attorneys’ fees and expenses) incurred by them without negligence or willful misconduct on their part in connection with
the acceptance and administration of this trust and the performance of their duties hereunder, including the costs and expenses
of enforcing this Contingent Convertible Securities Indenture (including this ‎‎Section
6.07 and the costs and expenses of defending themselves against any claims (whether asserted by any Holder, the Company or any
other Person). The Trustee shall notify the Company promptly of any claim for which it may seek indemnity. Failure by the Trustee
to so notify the Company shall not relieve the Company of its obligations hereunder. The Trustee shall have the right to employ
separate counsel in any such action or proceeding and participate in the investigation and defense thereof, and the Company shall
pay the reasonable fees and expenses of such separate counsel; provided, however, that the Trustee may only employ separate counsel
at the expense of the Company if in the judgment of the Trustee (i) a conflict of interest exists by reason of common representation
or (ii) there are legal defenses available to the Trustee that are different from or are in addition to those available to the
Company or if all parties commonly represented do not agree as to the action (or inaction) of counsel. The Company need not reimburse
any expense or indemnify against any loss, liability or expense incurred by the Trustee through the Trustee’s own negligence
or willful misconduct as determined by a competent U.S. or New York State court of competent jurisdiction in a final, non-appealable
judgment.

 

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(c) To secure the Company’s payment
obligations in this‎Section 6.07, the Trustee shall have a lien prior to the Holders
of the Contingent Convertible Securities on all money or property held or collected by the Trustee other than money or property
held in trust to pay principal of and interest on particular Contingent Convertible Securities. The Trustee’s right to receive
payment of any amounts due under this ‎‎Section 6.07 shall not be subordinate
to any other liability or indebtedness of the Company, and the Company’s obligations under this ‎Section
6.07 to the Trustee shall survive an Enforcement Event and conversion of Contingent Convertible Securities into Ordinary Shares.

 

(d) The Company’s obligations pursuant
to this ‎Section 6.07 shall survive an Enforcement Event, the payment of the Contingent
Convertible Securities, the discharge of this Contingent Convertible Securities Indenture, the resignation or removal of the Trustee
and/or the termination for any reason of this Contingent Convertible Securities Indenture. When the Trustee incurs expenses after
the occurrence of a Liquidation Event, the expenses are intended to constitute expenses of administration under any Liquidation
Event; provided, however, that this shall not affect the Trustee’s rights as set forth in this‎Section
6.07.

 

(e) If the Trustee is represented by separate
counsel due to a conflict of interest or its need for separate representation due to a need to assert defences, which are different
from the Company’s, in the Trustee’s sole discretion, the Trustee shall be entitled to enter into any settlement without
the written consent of the Company and any and all fees, costs and expenses of such separate legal representation of the Trustee
will be paid by the Company.

 

(f) As security for the performance of the
obligations of the Company under this Section, the Trustee shall have a senior lien to which the Contingent Convertible Securities
are hereby made subordinate, upon all property and funds held or collected by the Trustee as such, except funds held in trust for
the payment of principal of or interest, if any, on the Contingent Convertible Securities.

 

Section 6.08. Disqualification; Conflicting
Interests. If the Trustee has or shall acquire a conflicting interest within the meaning of the Trust Indenture Act, the Trustee
shall either eliminate such interest or resign, to the extent and in the manner provided by, and subject to the provisions of,
Section 310(b) of the Trust Indenture Act and this Contingent Convertible Securities Indenture.

 

Section 6.09. Corporate Trustee Required;
Eligibility. There shall at all times be a Trustee hereunder with respect to the series which shall be a corporation organized
and doing business under the laws of the United States, any State thereof or the District of Columbia, authorized under such laws
to exercise corporate trust powers, having a combined capital and surplus of at least U.S.$50,000,000, subject to supervision or
examination by Federal or State or District of Columbia authority and, if there be such corporation willing and able to act as
trustee on reasonable and customary terms, having its corporate trust office or agency in the Borough of Manhattan, The City of
New York, New York. If such corporation publishes reports of condition at least annually, pursuant to law or to the requirements
of said supervising or examining authority, then for the purposes of this Section, the combined capital and surplus of such corporation
shall be deemed to be its combined capital and surplus as set forth in its most recent report of condition so published. If at
any time the Trustee shall cease to be eligible in accordance with the provisions of this Section, it shall resign immediately
in the manner and with the effect hereinafter specified in this ‎Article 6.

 

Section 6.10. Resignation and Removal;
Appointment of Successor.

 

(a) The Trustee may resign at any time by
so notifying the Company. The Holders of a majority in principal amount of the Outstanding Contingent Convertible Securities may
remove the Trustee if an Enforcement Event has occurred and is continuing by so notifying the Trustee and may appoint a successor
Trustee reasonably acceptable to the Company. If the instrument of acceptance by a successor Trustee required by this ‎Section
6.10 shall not have been delivered to the Trustee within 30 days after the giving of such notice of removal, the Trustee may petition
at the expense of the Company any court of competent jurisdiction for the appointment of a successor Trustee with respect to the
Contingent Convertible Securities of such series.

 

(b) The Company shall remove the Trustee
if

 

(i) the Trustee fails to comply
with ‎Section 6.12;

 

(ii) the Trustee is adjudged bankrupt,
insolvent or in a similar status under applicable law;

 

(iii) a receiver or other public
officer takes charge of the Trustee or its property; or

 

(iv) the Trustee otherwise becomes
incapable of acting for any reason.

 

(c) If the Trustee resigns or is removed
by the Company or by the Holders of a majority in principal amount of the Outstanding Contingent Convertible Securities and such
Holders do not reasonably promptly appoint a successor Trustee, or if a vacancy exists in the office of the Trustee for any reason
(the Trustee in such event being referred to herein as the retiring Trustee), the Company shall promptly appoint a successor Trustee.
No resignation or removal of the Trustee and no appointment of a successor trustee shall be effective until the acceptance of appointment
by such successor Trustee in accordance with the provisions of this Contingent Convertible Securities Indenture.

 

    26

     

    

(d) A successor Trustee shall deliver a
written acceptance of its appointment to the retiring Trustee and to the Company. Thereupon, the resignation or removal of the
retiring Trustee shall become effective, and the successor Trustee shall have all the rights, powers and duties of the Trustee
under this Contingent Convertible Securities Indenture. The successor Trustee shall mail a notice of its succession to Holders.
The retiring Trustee shall promptly transfer all property held by it as Trustee to the successor Trustee, subject to the lien provided
for in ‎Section 6.07.

 

(e) If a successor Trustee does not take
office within thirty (30) days after the retiring Trustee resigns or is removed, the retiring Trustee or the Holders of 10% in
principal amount of the Outstanding Contingent Convertible Securities may petition, at the Company’s expense, any court of
competent jurisdiction for the appointment of a successor Trustee.

 

(f) If the Trustee fails to comply with
‎Section 6.12, any Holder may petition any court of competent jurisdiction for
the removal of the Trustee and the appointment of a successor Trustee.

 

(g) Notwithstanding the replacement of the
Trustee pursuant to this ‎Section 6.10, the Company’s obligations under ‎Section
6.07 shall continue for the benefit of the retiring Trustee.

 

Section 6.11. Successor Trustee by Merger.

 

(a) If the Trustee consolidates with, merges
or converts into, or transfers all or substantially all of its corporate trust business or assets to another Person or banking
association, the resulting, surviving or transferee Person without any further act shall be the successor Trustee.

 

(b) In case at the time such successor or
successors to the Trustee shall succeed to the trusts created by this Contingent Convertible Securities Indenture, any of the Contingent
Convertible Securities shall have been authenticated but not delivered, any such successor to the Trustee may adopt the certificate
of authentication of any predecessor trustee, and deliver such Contingent Convertible Securities so authenticated; and in case
at that time any of the Contingent Convertible Securities shall not have been authenticated, any successor to the Trustee may authenticate
such Contingent Convertible Securities either in the name of any predecessor hereunder or in the name of the successor to the Trustee;
and in all such cases such certificates shall have the full force as if such predecessor trustee had authenticated and delivered
such Contingent Convertible Securities.

 

Section 6.12. Eligibility; Disqualification.
The Trustee shall at all times satisfy any applicable requirements of Section 310(a) of the TIA. The Trustee shall have a combined
capital and surplus of at least U.S.$50 million as set forth in its most recent published annual report of condition. The Trustee
shall comply with any applicable requirements of Section 310(b) of the TIA; provided, however, that there shall be excluded from
the operation of Section 310(b)(1) of the TIA, if applicable, any indenture or indentures under which other securities or certificates
of interest or participation in other securities of the Company are outstanding if the requirements for such exclusion set forth
in Section 310(b)(1) of the TIA, to the extent applicable, are met.

 

Section 6.13. Preferential Collection
of Claims against the Company. The Trustee shall comply with Section 311(a) of the TIA, excluding any creditor relationship
listed in Section 311(b) of the TIA. A Trustee who has resigned or been removed shall be subject to Section 311(a) of the TIA to
the extent indicated.

 

Section 6.14. Appointment of Co-Trustee.

 

(a) The Trustee may, subject to the prior
written approval of the Company (such approval not to be unreasonably withheld) and unless there exists no Enforcement Event, appoint
an individual or institution as a separate trustee or co-trustee in the event that the Trustee (i) initiates litigation against
the Company under this Contingent Convertible Securities Indenture pursuant to a Liquidation Event and (ii) reasonably believes
that by reason of any present or future law of any jurisdiction it may not exercise any of the powers, rights or remedies herein
granted to the Trustee or hold title to the properties, in trust, as herein granted or take any action which may be desirable or
necessary in connection therewith. The following provisions of this ‎Section 6.14
are adopted to these ends.

 

(b) In the event that the Trustee appoints
an additional individual or institution as a separate trustee or co-trustee, all powers, rights and remedies contained in this
Contingent Convertible Securities Indenture to be exercised by or vested in or conveyed to the Trustee with respect thereto shall
be exercisable by and vest in such separate trustee or co-trustee, but only to the extent necessary to enable such separate trustee
or co-trustee to exercise such powers, rights and remedies, and only to the extent that the Trustee by the laws of any jurisdiction
is incapable of exercising such powers, rights and remedies, and every covenant and obligation necessary to the exercise thereof
by such separate trustee or co-trustee shall run to and be enforceable by either of them.

 

(c) Should any instrument in writing from
the Company be required by the separate trustee or co-trustee so appointed by the Trustee for more fully and certainly vesting
in and confirming to it such properties, rights, powers, trusts, duties and obligations, any and all such instruments in writing
shall, on reasonable request, be executed, acknowledged and delivered by the Company; provided that if a Liquidation Event shall
have occurred and be continuing, if the Company does not execute any such instrument within fifteen (15) days after request therefor,
the Trustee shall be empowered as an attorney-in-fact for the Company to execute any such instrument in the Company’s name
and stead. In case any separate trustee or co-trustee or a successor to either shall die, become incapable of acting, resign or
be removed, all the estates, properties, rights, powers, trusts, duties

 

    27

     

    

and obligations of such separate trustee or
co-trustee, so far as permitted by law, shall vest in and be exercised by the Trustee until the appointment of a new trustee or
successor to such separate trustee or co-trustee.

 

(d) Every separate trustee and co-trustee
shall, to the extent permitted by law, be appointed and act subject to the following provisions and conditions:

 

(i) all rights and powers conferred
or imposed upon the Trustee shall be conferred or imposed upon and may be exercised or performed by such separate trustee or co-trustee;
and

 

(ii) no trustee hereunder shall
be personally liable by reason of any act or omission of any other trustee hereunder.

 

(e) Any notice, request or other writing
given to the Trustee shall be deemed to have been given to each of the then separate trustees and co-trustees, as effectively as
if given to each of them. Every instrument appointing any separate trustee or co-trustee shall refer to this Contingent Convertible
Securities Indenture and the conditions of this ‎Article 6.

 

(f) Any separate trustee or co-trustee may
at any time appoint the Trustee as its agent or attorney-in-fact with full power and authority, to the extent not prohibited by
law, to do any lawful act under or in respect of this Contingent Convertible Securities Indenture on its behalf and in its name.

 

Section 6.15. Appointment of Authenticating
Agent. The Trustee may at any time appoint an Authenticating Agent or Agents with respect to the series of Contingent Convertible
Securities that shall be authorized to act on behalf of the Trustee to authenticate Contingent Convertible Securities of such series
upon original issue, or issued upon exchange, registration of transfer or partial redemption thereof or in lieu of destroyed, lost
or stolen Contingent Convertible Securities, and Contingent Convertible Securities so authenticated shall be entitled to the benefits
of this Contingent Convertible Securities Indenture and shall be valid and obligatory for all purposes as if authenticated by the
Trustee hereunder. Wherever reference is made in this Contingent Convertible Securities Indenture to the authentication and delivery
of Contingent Convertible Securities by the Trustee or the Trustee’s certificate of authentication, such reference shall
be deemed to include authentication and delivery on behalf of the Trustee by an Authenticating Agent and a certificate of authentication
executed on behalf of the Trustee by an Authenticating Agent. Each Authenticating Agent shall be acceptable to the Company and
shall at all times be a corporation or banking association organized and doing business under the laws of the United States, any
State thereof or the District of Columbia, authorized under such laws to act as Authenticating Agent, having a combined capital
and surplus of not less than U.S.$50,000,000 and subject to supervision or examination by Federal or State or District of Columbia
authority. If such Authenticating Agent publishes reports of condition at least annually, pursuant to law or to the requirements
of said supervising or examining authority, then for the purposes of this Section, the combined capital and surplus of such Authenticating
Agent shall be deemed to be its combined capital and surplus as set forth in its most recent report of condition so published.
If at any time an Authenticating Agent shall cease to be eligible in accordance with the provisions of this ‎Section 6.15,
such Authenticating Agent shall resign immediately in the manner and with the effect specified in this Section.

 

Any Person into which an Authenticating
Agent may be merged or converted or with which it may be consolidated, or any Person resulting from any merger, conversion or consolidation
to which such Authenticating Agent shall be a party, or any Person succeeding to the corporate agency or corporate trust business
of an Authenticating Agent, shall continue to be an Authenticating Agent, provided such corporation or national banking association
shall be otherwise eligible under this ‎Section
6.15, without the execution or filing of any paper or any further act on the part of the Trustee or the Authenticating Agent.

 

An Authenticating Agent may resign at any
time by giving written notice thereof to the Trustee and to the Company. The Trustee may at any time terminate the agency of an
Authenticating Agent by giving written notice thereof to such Authenticating Agent and to the Company. Upon receiving such a notice
of resignation or upon such a termination, or in case at any time such Authenticating Agent shall cease to be eligible in accordance
with the provisions of this ‎Section 6.15,
the Trustee may appoint a successor Authenticating Agent that shall be acceptable to the Company and shall give notice to the Holders
of Contingent Convertible Securities in the manner and to the extent provided in ‎Section
1.06. Any successor Authenticating Agent upon acceptance of its appointment hereunder shall become vested with all the rights,
powers and duties of its predecessor hereunder, with like effect as if originally named as an Authenticating Agent. No successor
Authenticating Agent shall be appointed unless eligible under the provisions of this ‎Section
6.15.

 

The Company agrees to pay to each Authenticating
Agent from time to time reasonable compensation for its services under this ‎Section
6.15.

 

If an appointment with respect to the series
is made pursuant to this Section, the Contingent Convertible Securities of such series may have endorsed thereon, in lieu of the
Trustee’s certificate of authentication, an alternate certificate of authentication in the following form:

 

This is one of the Contingent Convertible
Securities referred to in the within-mentioned Contingent Convertible Securities Indenture.

 

    28

     

    

 

	
THE BANK OF NEW YORK MELLON

as Trustee

	 
	By:	 
	 	as Authenticating Agent
	 	 	 

 

	By:	 
	 	Authorized Signatory
	 	 	 

 

Article
7

Holders Lists and Reports by Trustee and Company

 

Section 7.01. Company to Furnish Trustee
Names and Addresses of Holders. The Company, with respect to the series of Contingent Convertible Securities, shall furnish
or cause to be furnished to the Trustee

 

(a) quarterly, not more than 15 days after
each Regular Record Date (or after each of the dates to be specified for such purpose for non-interest bearing Contingent Convertible
Securities and Contingent Convertible Securities on which interest is paid less frequently than quarterly as contemplated by ‎Section
3.01), a list, in such form as the Trustee may reasonably require, of the names and addresses of the Holders of Contingent Convertible
Securities as of such Regular Record Date or such specified date, and

 

(b) at such other times as the Trustee may
request in writing, within thirty (30) days after the receipt by the Company of any such request, a list of similar form and content
as of a date not more than 15 days prior to the time such list is furnished.

 

The Company need not furnish or cause to
be furnished to the Trustee pursuant to this ‎Section
7.01 the names and addresses of Holders of Contingent Convertible Securities so long as the Trustee acts as Contingent Convertible
Security Registrar with respect to such series of Contingent Convertible Securities.

 

Section 7.02. Preservation of Information;
Communication to Holders.

 

(a) The Trustee shall preserve, in as current
a form as is reasonably practicable, the names and addresses of Holders (i) contained in the most recent list furnished to the
Trustee as provided in ‎Section 7.01 and (ii) received by the Trustee in its capacity
as Paying Agent or Contingent Convertible Security Registrar (if so acting). The Trustee may destroy any list furnished to it as
provided in ‎Section 7.01 upon receipt of a new list so furnished.

 

(b) The rights of the Holders of Contingent
Convertible Securities of the series to communicate with other Holders with respect to their rights under this Contingent Convertible
Securities Indenture or under the Contingent Convertible Securities, and the corresponding rights and privileges of the Trustee,
shall be as provided by the Trust Indenture Act.

 

(c) Every Holder, by receiving and holding
a Contingent Convertible Security, agrees with the Company and the Trustee that neither the Company nor the Trustee nor any agent
of any of them shall be held accountable by reason of the disclosure of any such information as to the names and addresses of the
Holders in accordance with ‎Section 7.02(b) or otherwise made pursuant to the Trust
Indenture Act.

 

Section 7.03. Reports by Trustee.

 

(a) Within 60 days after May 15 of each
year commencing with the first May 15 following the date hereof, so long as any Contingent Convertible Securities are Outstanding
hereunder, if required by Section 313(a) of the Trust Indenture Act, the Trustee shall transmit to Holders, pursuant to Section
313(c) of the Trust Indenture Act, a brief report dated as of such June 15 with respect to any of the events specified in said
Section 313(a) which may have occurred since the later of the immediately preceding June 15 and the date of this Contingent Convertible
Securities Indenture.

 

(b) The Trustee shall transmit the reports
required by Section 313(a) of the Trust Indenture Act at the times specified therein.

 

(c) A copy of each such report shall, at
the time of such transmission to Holders, be filed by the Trustee with each securities exchange upon which the Trustee has been
notified that the Contingent Convertible Securities are listed, with the Commission and with the Company. The Company shall notify
the Trustee when Contingent Convertible Securities are listed on any securities exchange.

 

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(d) If not otherwise available on the Company’s
website, the Company shall furnish the Trustee with interim and annual reports, and upon receipt thereof, and at the direction
of the Company, the Trustee shall mail such reports to all record holders of Contingent Convertible Securities. In addition, the
Company shall furnish the Trustee with all notices of meetings at which holders of Contingent Convertible Securities of the series
are entitled to vote, and all other reports and communications that are made generally available to holders of Contingent Convertible
Securities. The Trustee shall, at the Company’s expense, make such notices, reports and communications available for inspection
by holders of Contingent Convertible Securities in such manner as the Company may determine and, in the case of any notice received
by the Trustee in respect of any meeting at which holders of Contingent Convertible Securities of the series are entitled to vote,
at the direction of the Company, shall mail to all such record holders of Contingent Convertible Securities, at the Company’s
expense, a notice containing a summary of the information set forth in such notice of meeting.

 

Section 7.04. Reports by Company.
The Company shall

 

(a) file with the Trustee, within 15 days
after the Company is required to file the same with the Commission, copies of the annual reports and of the information, documents
and other reports (or copies of such portions of any of the foregoing as the Commission may from time to time by rules and regulations
prescribe) that the Company may be required to file with the Commission pursuant to Section 13 or Section 15(d) of the Exchange
Act; or, if the Company is not required to file information, documents or reports pursuant to either of such Sections, then it
shall file with the Trustee and the Commission, in accordance with rules and regulations prescribed from time to time by the Commission,
such of the supplementary and periodic information, documents and reports which may be required pursuant to Section 13 of the Exchange
Act in respect of a security listed and registered on a national securities exchange as may be prescribed from time to time in
such rules and regulations. Delivery of such reports, information and documents to the Trustee is for informational purposes only
and the Trustee’s receipt of such shall not constitute actual or constructive notice of any information contained therein
or determinable from information contained therein, including the Company’s compliance with any of its covenants hereunder
(as to which the Trustee is entitled to rely exclusively on an Officer’s Certificate);

 

(b) file with the Trustee and the Commission,
in accordance with rules and regulations prescribed from time to time by the Commission, such additional information, documents
and reports with respect to compliance by the Company with the conditions and covenants of this Contingent Convertible Securities
Indenture as may be required from time to time by such rules and regulations. Delivery of such reports, information and documents
to the Trustee is for informational purposes only, and the Trustee’s receipt of such shall not constitute constructive notice
of any information contained therein or determinable from information contained therein, including the Company’s compliance
with any of its covenants hereunder (as to which the Trustee is entitled to rely exclusively on an Officer’s Certificate);
and

 

(c) transmit to Holders, in the manner and
to the extent required by the Trust Indenture Act, within thirty (30) days after the filing thereof with the Trustee, such summaries
of any information, documents and reports required to be filed by the Company pursuant to paragraphs ‎(a)
and ‎(b) of this Section as may be required by rules and regulations prescribed
from time to time by the Commission.

 

Article
8

Supplemental Indentures

 

Section 8.01. Banco de México
Authorization. No modification shall be effected to this Contingent Convertible Securities Indenture or any supplemental indenture
hereto or in relation to the Contingent Convertible Securities issued hereunder, unless the Company has received prior authorization
from Banco de México. The Trustee is entitled to request and rely on an Officer’s Certificate as to the satisfaction
of this condition precedent to any modification without further enquiry.

 

Section 8.02. Supplemental Indenture
without Consent of Holders. Subject to ‎Section 8.01, without the consent of any Holders, the Company, when authorized
by a Board Resolution, and the Trustee, at any time and from time to time, may enter into one or more indentures supplemental hereto,
in form satisfactory to the Trustee, for any of the following purposes:

 

(a) to evidence the succession of another
corporation to the Company and the assumption by any such successor of the covenants of the Company herein and in the Contingent
Convertible Securities;

 

(b) to add to the covenants of the Company
for the benefit of the Holders of the series of Contingent Convertible Securities or to surrender any right or power herein conferred
upon the Company;

 

(c) to add any additional Enforcement Events;

 

(d) to add to, change or eliminate any of
the provisions of this Contingent Convertible Securities Indenture, or any supplemental indenture; provided that any such change
or elimination shall become effective only when there is no Contingent Convertible Security Outstanding of the series created prior
to the execution of such supplemental indenture effecting such change or elimination that is entitled to the benefit of such provision,
and adversely affected by such addition, change or elimination;

 

(e) to establish the form or terms of Contingent
Convertible Securities of the series as permitted by Sections ‎2.01 or ‎3.01;

 

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(f) to change any Place of Payment, so long
as the Place of Payment as required by ‎Section 3.01 is maintained;

 

(g) to cure any ambiguity or to correct
or supplement any provision herein which may be defective or inconsistent with any other provision herein or in any supplemental
indenture;

 

(h) to vary, substitute or change specified
terms of the series of Contingent Convertible Securities subject to the conditions set forth under ‎Section
3.01; provided that such action shall not adversely affect the interests of the Holders of Contingent Convertible Securities of
the series in any material respect;

 

(i) to make any other provisions with respect
to matters or questions arising under this Contingent Convertible Securities Indenture; provided that such action shall not adversely
affect the interests of the Holders of Contingent Convertible Securities of the series in any material respect;

 

(j) to evidence and provide for the acceptance
of an appointment hereunder by a successor Trustee with respect to the Contingent Convertible Securities of the series and to add
to or change any of the provisions of this Contingent Convertible Securities Indenture as shall be necessary to provide for or
facilitate the administration of the trusts hereunder by more than one Trustee, pursuant to the requirements of ‎Section
6.11(b);

 

(k) to change or eliminate any provision
of this Contingent Convertible Securities Indenture as permitted by ‎Section 1.07;
or

 

(l) with respect to any Contingent Convertible
Security (including a Global Security) issued on or after the date hereof, to amend any such Contingent Convertible Security to
conform to the description of the terms of such Contingent Convertible Security in the prospectus, prospectus supplement, product
supplement, pricing supplement or any other similar offering document related to the offering of such Contingent Convertible Security.

 

Section 8.03. Supplemental Indentures
with Consent of Holders. Subject to ‎Section 8.01, with the consent of the Holders of not less than a majority in aggregate
principal amount of the Outstanding Contingent Convertible Securities of the series affected by such supplemental Contingent Convertible
Securities Indenture (voting as a class), by Act of said Holders delivered to the Company and the Trustee, the Company, when authorized
by a Board Resolution, and the Trustee may enter into an indenture or indentures supplemental hereto for the purpose of adding
any provisions to or changing in any manner or eliminating any of the provisions of this Contingent Convertible Securities Indenture
or of modifying in any manner the rights of the Holders of Contingent Convertible Securities of such series under this Contingent
Convertible Securities Indenture; provided, however, that no such supplemental indenture may, without the consent of 100% of the
Holders of the Outstanding Contingent Convertible Securities affected thereby and the approval of 75% of the members of the Board
of Directors,

 

(a) change the Stated Maturity, if any,
of any principal amount or any interest amounts in respect of any such Contingent Convertible Security, change the terms of any
Contingent Convertible Security to include a Stated Maturity or reduce the principal amount thereof or reduce the rate of interest,
if any, thereon, or reduce the amount of principal of an Original Issue Discount Security that would be due and payable upon an
acceleration of the Maturity thereof, if any, or change the obligation of the Company (or its successors) to pay additional interest,
if any (except as permitted by ‎Section 8.02(a) or as contemplated by any provision
relating to consolidation, merger, sale or transfer of assets in any supplemental indenture) or change the currency of payment
of the principal amount of, or interest on, any such Contingent Convertible Security, or impair the right to institute suit for
the enforcement of any such payment on or after the Stated Maturity thereof or the date any such payment is otherwise due and payable
(or, in the case of redemption, on or after the Redemption Date), or modify any other payment provision of any Contingent Convertible
Security;

 

(b) reduce the percentage in aggregate principal
amount of the Outstanding Contingent Convertible Securities of the series that is required for the consent of the Holders in order
to modify or amend this Contingent Convertible Securities Indenture or any supplemental indenture, or the consent of whose Holders
is required for any waiver (of compliance with certain provisions of this Contingent Convertible Securities Indenture or of certain
defaults hereunder and their consequences) provided for in this Contingent Convertible Securities Indenture;

 

(c) modify any of the provisions of this
Section except to increase any such percentage or to provide that certain other provisions of this Contingent Convertible Securities
Indenture cannot be modified or waived without the consent of the Holder of each Outstanding Contingent Convertible Security affected
thereby; provided, however, that this clause shall not be deemed to require the consent of any Holder with respect to changes in
the references to the “Trustee” and concomitant changes in this Section, or the deletion of this proviso, in accordance
with the requirements of ‎Section 6.10 and ‎8.02(k);

 

(d) change the governing law of any Contingent
Convertible Security; or

 

(e) change in any manner adverse to the
interests of the Holders of any Contingent Convertible Securities, the subordination provisions of the Contingent Convertible Securities,
or the provisions relating to consolidation, merger, conveyance or transfer of the Company and/or substantially all of its property,
or the provisions dealing with bankruptcy or liquidation of the Company, or the terms and conditions of the obligations of the
Company in respect of the due and punctual payment of any amounts due and payable on the Contingent Convertible Securities.

 

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It shall not be necessary for any Act of
Holders under this Section to approve the particular form of any proposed supplemental indenture, but it shall be sufficient if
such Act shall approve the substance thereof.

 

Section 8.04. Execution of Supplemental
Indentures. In executing, or accepting the additional trusts created by, any supplemental indenture permitted by this Article
or the modifications thereby of the trusts created by this Contingent Convertible Securities Indenture, the Trustee shall be entitled
to receive, and (subject to ‎Section 6.01) shall be fully protected in relying upon, an Opinion of Counsel stating that the
execution of such supplemental indenture is authorized or permitted by this Contingent Convertible Securities Indenture and constitutes
a legal, valid, binding and enforceable obligation of the Company subject to customary exceptions. The Trustee may, but shall not
be obliged to, enter into any such supplemental indenture that affects the Trustee’s own rights, duties or immunities under
this Contingent Convertible Securities Indenture or otherwise.

 

Section 8.05. Effect of Supplemental
Indentures. Upon the execution of any supplemental indenture under this Article, this Contingent Convertible Securities Indenture
shall be modified in accordance therewith, and such supplemental indenture shall form a part of this Contingent Convertible Securities
Indenture for all purposes; and every Holder of Contingent Convertible Securities theretofore or thereafter authenticated and delivered
hereunder shall be bound thereby, except as otherwise expressed therein.

 

Section 8.06. Conformity with Trust Indenture
Act. Every supplemental indenture executed pursuant to this Article shall conform to the requirements of the Trust Indenture
Act as then in effect.

 

Section 8.07. Reference in Contingent
Convertible Securities to Supplemental Indentures. Contingent Convertible Securities of the series authenticated and delivered
after the execution of any supplemental indenture pursuant to this Article may, and shall if required by the Trustee, bear a notation
in form approved by the Trustee as to any matter provided for in such supplemental indenture. If the Company shall so determine,
new Contingent Convertible Securities of the series so modified as to conform, in the opinion of the Trustee and the Company, to
any such supplemental indenture may be prepared and executed by the Company and such Contingent Convertible Securities may be authenticated
and delivered by the Trustee in exchange for Outstanding Contingent Convertible Securities of such series.

 

Section 8.08. Notification of Modification
or Supplemental Indenture. No such modification shall be effected in relation to the series of Contingent Convertible Securities
pursuant to this Article or ‎Section 3.13 herein, unless the Company has received prior authorization from Banco de México.
The Trustee is entitled to request and rely on an Officer’s Certificate as to the satisfaction of this condition precedent
to any modification without further enquiry.

 

Article
9

Covenants

 

Section 9.01. Payment of Principal and
Interest. The Company covenants and agrees for the benefit of the series of Contingent Convertible Securities that it shall
(subject to any subordination provisions applicable to the Contingent Convertible Securities of that series pursuant to ‎Section
11.01 and ‎Section 3.01 hereof) duly and punctually pay the principal of and interest, if any, on, the Contingent Convertible
Securities of that series in accordance with the terms of the Contingent Convertible Securities and this Contingent Convertible
Securities Indenture.

 

Section 9.02. Maintenance of Office or
Agency. The Company shall maintain in each Place of Payment for the series of Contingent Convertible Securities an office or
agency where Contingent Convertible Securities of that series may be presented or surrendered for payment, where Contingent Convertible
Securities of that series may be surrendered for registration of transfer or exchange and where notices and demands to or upon
the Company in respect of the Contingent Convertible Securities of that series and this Contingent Convertible Securities Indenture
may be served; provided, however, that at the option of the Company in the case of Contingent Convertible Securities of such series,
payment of any interest thereon may be made by check mailed to the address of the Person entitled herein as such address shall
appear in the Contingent Convertible Security Register. With respect to the Contingent Convertible Securities of the series, such
office or agency in each Place of Payment shall be specified as contemplated by ‎Section 3.01, and if not so specified, initially
shall be the Corporate Trust Office of the Trustee. Unless otherwise specified pursuant to ‎Section 3.01, the Company shall
maintain in the Borough of Manhattan, The City of New York, an office or agency where notices and demands to or upon the Company
in respect of Contingent Convertible Securities of the series and this Contingent Convertible Securities Indenture may be served.
The Company shall give prompt written notice to the Trustee of the location, and any change in the location, of such office or
agency. If at any time the Company shall fail to maintain any such required office or agency or shall fail to furnish the Trustee
with the address thereof, such presentations, surrenders, notices and demands may be made or served at the Corporate Trust Office
of the Trustee. The Company hereby appoints the Trustee as its agent to receive all presentations, surrenders, notices and demands.

 

The Company may also from time to time designate
one or more other offices or agencies (in or outside the Borough of Manhattan, The City of New York) where the Contingent Convertible
Securities of the series may be presented or surrendered for any or all such purposes and may from time to time rescind such designations;
provided, however, that no such designation or rescission shall in any manner relieve the Company of any obligation to maintain
an office or agency in each Place of Payment (except as otherwise indicated in this Section) for Contingent Convertible Securities
of the series for such purposes.

 

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The Company shall give prompt written notice
to the Trustee of any such designation or rescission and of any change in the location of any such other office or agency.

 

Section 9.03. Money for Payments to Be
Held in Trust. If the Company shall at any time act as Paying Agent with respect to the Contingent Convertible Securities of
the series, it shall, on or before each due date for payment of the principal of or interest, if any, on any of the Contingent
Convertible Securities of that series, segregate and hold in trust for the benefit of the Persons entitled thereto a sum sufficient
to pay the principal or interest, if any, so becoming due until such sums shall be paid to such Persons or otherwise disposed of
as herein provided and shall promptly notify the Trustee of its failure so to act.

 

Whenever the Company shall have one or more
Paying Agents for the series of Contingent Convertible Securities, it shall, prior to each due date for payment of the principal
of or interest, if any, on any Contingent Convertible Securities of that series deposit with a Paying Agent a sum sufficient to
pay the principal or interest, if any, so becoming due, such sum to be held in trust for the benefit of the Persons entitled to
such principal or interest, and (unless such Paying Agent is the Trustee) the Company shall promptly notify the Trustee of its
action or its failure so to act. Unless otherwise specified as contemplated by ‎Section
3.01, the Trustee shall be the Company’s Paying Agent. The Company shall cause each Paying Agent for the series of Contingent
Convertible Securities other than the Trustee to execute and deliver to the Trustee an instrument in which such Paying Agent shall
agree with the Trustee, subject to the provisions of this Section, that such Paying Agent shall

 

(a) hold all sums held by it for the payment
of the principal of or interest, if any, on Contingent Convertible Securities of that series in trust for the benefit of the Persons
entitled thereto until such sums shall be paid to such Persons or otherwise disposed of as herein provided;

 

(b) give the Trustee notice of any default
or Enforcement Event by the Company (or any other obligor upon the Contingent Convertible Securities of that series) in the making
of any payment, when due and payable, of principal of or interest, if any, on Contingent Convertible Securities of that series;
and

 

(c) at any time during the continuance of
any such default, upon the written request of the Trustee, forthwith pay to the Trustee all sums so held in trust by such Paying
Agent.

 

The Company may at the time, for the purpose
of obtaining the satisfaction and discharge of this Contingent Convertible Securities Indenture or for any other purpose, pay,
or by Company Order direct any Paying Agent to pay, to the Trustee all sums held in trust by the Company or such Paying Agent,
such sums to be held by the Trustee upon the same trusts as those upon which such sums were held by the Company or such Paying
Agent; and, upon such payment by any Paying Agent to the Trustee, such Paying Agent shall be released from all further liability
with respect to such money.

 

If any money deposited with the Trustee
or any Paying Agent, or then held by the Company, in trust for the payment of the principal of or interest, if any, on any Contingent
Convertible Security of the series remains unclaimed for two years after such principal or interest, if any, have become due and
payable, the Trustee or such Paying Agent shall, upon written request by the Company, return the money to the Company, subject
to the applicable unclaimed property law. The Holder of such Contingent Convertible Security shall thereafter, as an unsecured
general creditor, look only to the Company for payment thereof, and all liability of the Trustee or such Paying Agent with respect
to such unclaimed money, unless an applicable unclaimed property law designates another Person, shall thereupon cease.

 

Section 9.04. Corporate Existence.
Subject to any consolidation, merger, sale or transfer of assets, the Company will do or cause to be done all things necessary
to preserve and keep in full force and effect its corporate existence.

 

Section 9.05. Maintenance of Approvals.
The Company shall use its reasonable best efforts to maintain in full force and effect all approvals, consents or licenses of any
governmental authority which are necessary under the laws of Mexico or any other jurisdiction having jurisdiction over the Company
or the Company’s business, assets or property and are necessary in connection with the performance of the Company’s
obligations under this Contingent Convertible Securities Indenture and any Contingent Convertible Securities issued hereunder.
The Company will submit this Contingent Convertible Securities Indenture and any supplemental indenture to the CNBV for execution
by the CNBV as evidence of the transaction contemplated herein as set forth under Article 30 of the Mexican Financial Groups Law
and Article 64 of the Mexican Banking Law. The Company shall deliver to Banco de México all documents required in
order to receive the authorization of Banco de México for the issuance of the series of Contingent Convertible Securities
within the term set forth therein. The Company will deliver to the CNBV any notice and all other documents required by Article
7 of the Mexican Securities Market Law and the regulations thereunder.

 

Section 9.06. Statement as to Compliance.
The Company shall deliver to the Trustee within 120 days after the end of each fiscal year commencing in 2016 a certificate in
compliance with Section 314(a)(4) of the Trust Indenture Act.

 

Section 9.07. Original Issue Document.
The Company shall provide to the Trustee on a timely basis such information, if any, as the Trustee requires to enable the Trustee
to prepare and file any form required to be submitted by the Company with the Internal Revenue Service and the Holders of the Contingent
Convertible Securities relating to any original issue discount for U.S. federal income tax purposes.

 

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Article
10

Redemption of Contingent Convertible Securities

 

Section 10.01. Applicability of Article.
Contingent Convertible Securities of the series shall be redeemable in accordance with their terms and (except as otherwise specified
pursuant to ‎Section 3.01 in respect of the series of Contingent Convertible Securities) in accordance with this ‎Article
10. Contingent Convertible Securities of the series may not be redeemed except in accordance with provisions of applicable law
and applicable provisions of the Mexican Capitalization Requirements.

 

Section 10.02. Election to Redeem; Notice
to Trustee. The Company shall evidence its election to redeem the series of Contingent Convertible Securities (in whole or
in part, as the case may be) by a Board Resolution delivered at the time notice of redemption is given to the Holders. If the Company
elects to have the Trustee give any notice of redemption in respect of the series of Contingent Convertible Securities, then the
Company shall deliver to the Trustee, not less than forty (40) days or more than sixty (60) days prior to the Redemption Date (unless
the Trustee agrees to a shorter period in writing), a notice requesting that the Trustee select the Contingent Convertible Securities
of such series to be redeemed and/or give notice of redemption and setting forth the information required by ‎Section 10.05.
If the Company elects to have the Trustee give notice of redemption, the Trustee shall give the notice in the name of the Company
and at the Company’s expense.

 

Section 10.03. Accrual of Interest. On
and after any applicable Redemption Date, interest, if any, on the series of Contingent Convertible Securities or any portion of
the Contingent Convertible Securities called for redemption will cease to accrue (unless payment and performance of all amounts
and obligations due by the Company are not properly made, in which event interest, if any, will continue to accrue on the Contingent
Convertible Securities until such payment and performance has been properly and duly made). At least one (1) Business Day prior
to the applicable Redemption Date, by 11:00 a.m. New York City time, the Company shall deposit with the Trustee funds sufficient
to pay the Redemption Price and accrued and unpaid interest (and not canceled), if any, to the applicable Redemption Date, on the
Contingent Convertible Securities subject to redemption. If the applicable Redemption Date falls after a record date but on or
prior to the corresponding Interest Payment Date, the Company shall pay accrued interest, if any, to the Holder of record on the
corresponding record date, which may or may not be the person who will receive payment of the Redemption Price (which shall exclude
such accrued interest).

 

Section 10.04. Selection by Trustee of
Contingent Convertible Securities to Be Redeemed. Unless otherwise provided by ‎Section 3.01 with respect to the series
of Contingent Convertible Securities, if fewer than all of the Contingent Convertible Securities of the series are to be redeemed,
the particular Contingent Convertible Securities to be redeemed that are not held through DTC shall be selected by the Trustee
by lot, pro rata, or by such other method as the Trustee shall deem fair and appropriate; provided, however, that Global Securities
to be redeemed that are held through DTC shall be selected by DTC, as applicable, in accordance with its procedures.

 

Section 10.05. Notice of Redemption.
Unless otherwise provided by ‎Section 3.01 with respect to the series of Contingent Convertible Securities, in the event that
the Company elects to redeem the Contingent Convertible Securities pursuant to this Article and has received approval from Banco
de México, the Company shall or shall cause the Trustee to mail notice of any such redemption, in the manner provided
for in ‎Section 1.06, not less than thirty (30) calendar days but not more than sixty (60) calendar days prior to the Redemption
Date to each Holder. If the Company itself gives the notice, it shall also deliver a copy to the Trustee. All notices of a redemption
shall state

 

(a) the Redemption Date;

 

(b) the Redemption Price;

 

(c) that on the Redemption Date, the Redemption
Price and any accrued and unpaid (and not canceled) interest payable up to (but excluding) the Redemption Date as provided in ‎Section
10.06(b) will become due and payable in respect of each Contingent Convertible Security to be redeemed, and, unless payment and
performance of all amounts and obligations due by the Company are not properly made, that interest, if any, on each Contingent
Convertible Security, or the portion of each Contingent Convertible Security, to be redeemed, will cease to accrue on and after
the Redemption Date;

 

(d) the place or places where a Holder must
surrender the Holder’s Contingent Convertible Securities for payment of the Redemption Price; and

 

(e) the CUSIP or ISIN number, if any, listed
in the notice or printed on the Contingent Convertible Securities, and that no representation is made as to the accuracy or correctness
of such CUSIP or ISIN number.

 

Section 10.06. Deposit of Redemption
Price.

 

(a) Prior to 11:00 a.m. New York City time
on the Business Day prior to the relevant Redemption Date, the Company shall deposit with the Trustee or with a Paying Agent (or,
if the Company is acting as Paying Agent, segregate and hold in trust) an amount of money in immediately available funds sufficient
to pay the Redemption Price of, and accrued and unpaid interest on, all the Contingent Convertible Securities that the Company
is redeeming on that date.

 

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(b) Interest payable on the Redemption Date
shall be payable to the Holders on the relevant Regular Record Date.

 

(c) If notice of redemption shall have been
given and funds deposited with the Trustee to pay the applicable Redemption Price for the Contingent Convertible Securities being
redeemed, then upon the date of such deposit, all rights of the Holders of the Contingent Convertible Securities shall cease with
respect to the portion of Contingent Convertible Securities being redeemed, except the right of the Holders of the Contingent Convertible
Securities to receive the applicable Redemption Price, but without interest on such Redemption Price, and the Contingent Convertible
Securities so redeemed shall cease to be Outstanding. In the event that any Redemption Date in respect of the Contingent Convertible
Securities is not a Business Day, then the applicable Redemption Price payable on such date shall be paid on the next succeeding
day that is a Business Day (without any interest or other payment in respect of any such delay), with the same force and effect
as if made on such Redemption Date. In the event that payment of the applicable Redemption Price is improperly withheld or refused
and not paid by the Company, (i) interest due on the Contingent Convertible Securities being redeemed shall continue to accrue
at the then applicable rate, from the Redemption Date originally established by the Company to the date such applicable Redemption
Price is actually paid, and (ii) the actual payment date shall be the Redemption Date for purposes of calculating the applicable
Redemption Price.

 

Section 10.07. Contingent Convertible
Securities Payable on Redemption Date. If the Company, or the Trustee on behalf of the Company, gives notice of redemption
in accordance with this ‎Article 10 and subject to any provisions in a supplemental indenture, the Contingent Convertible Securities,
or the portions of Contingent Convertible Securities, if applicable, called for redemption, shall, on the Redemption Date, become
due and payable at the Redemption Price specified in the notice (together with accrued and unpaid (and not canceled) interest,
if any, to (but excluding) the Redemption Date), and from and after the Redemption Date (unless the Company shall default in the
payment of the Redemption Price and accrued interest), the Contingent Convertible Securities or the portions of Contingent Convertible
Securities, if applicable, shall cease to bear interest. Upon surrender of any Contingent Convertible Securities for redemption
in accordance with the notice, by 11:00 a.m. New York City time, to the extent funds are legally available, with respect to the
Contingent Convertible Securities being redeemed and held by DTC or its nominee, the Trustee or the Paying Agent shall pay to DTC
for further distribution to its participants the Redemption Price, together with accrued and unpaid (and not canceled) interest,
if any, to the Redemption Date (subject to the rights of Holders of record on the relevant Regular Record Date to receive interest
due in respect of an Interest Payment Date occurring on or prior to the Redemption Date). With respect to any Contingent Convertible
Securities being redeemed and held in certificated form, the Trustee, to the extent funds are legally available, shall pay the
Redemptin Price to the holders thereof upon surrender of their certificates evidencing the Contingent Convertible Securities. If
the Company shall fail to pay any Contingent Convertible Securities called for redemption upon its surrender for redemption, the
principal shall, until paid, bear interest from the Redemption Date at the rate borne by the Contingent Convertible Securities.

 

Section 10.08. Contingent Convertible
Securities Redeemed in Part. Any Contingent Convertible Security
which is to be redeemed only in part shall be surrendered at a Place of Payment therefor (with, only in the case of Contingent
Convertible Securities, if the Company or the Trustee so requires, due endorsement by, or a written instrument of transfer in form
satisfactory to the Company and the Trustee duly executed by, the Holder thereof or his attorney duly authorized in writing), and
the Company shall execute, and the Trustee shall authenticate and deliver to the Holder of such Contingent Convertible Security
without service charge, a new Contingent Convertible Security or Contingent Convertible Securities of the same series of any authorized
denomination as requested by such Holder, in aggregate principal amount equal to and in exchange for the unredeemed portion of
the principal of the Contingent Convertible Security so surrendered.

 

Article
11

Subordination of Contingent Convertible Securities

 

Section 11.01. Contingent Convertible
Securities Subordinate to Certain Other Claims of Creditors of the Company.

 

(a) The Contingent Convertible Securities
of the series shall constitute the Company’s direct, unsecured and subordinated obligations, ranking equally without any
preference among themselves. The supplemental indenture with respect to the series of Contingent Convertible Securities shall provide
that the payment of the principal of and interest, if any, on the series of Contingent Convertible Securities shall be subordinated
to the extent and in the manner described in such supplemental indenture, to the claims of the holders of certain other present
and future obligations of the Company.

 

(b) The provisions of this ‎Article
11 shall apply only to rights or claims payable under ‎Section 11.01(a) or to amounts
payable pursuant thereto and under any Contingent Convertible Securities of the series and nothing herein shall affect or prejudice
the payment of the costs, charges, expenses, liabilities, indemnity or remuneration of the Trustee under this Contingent Convertible
Securities Indenture or otherwise, the first lien rights of the Trustee under ‎Section
5.05 and ‎6.05 hereof, or the rights and remedies of the Trustee in respect thereof.

 

(c) The provisions of this ‎Article
11 shall not be applicable to any amounts in respect of any of the Contingent Convertible Securities of the series for the payment
of which funds have been deposited in trust with the Trustee or any Paying Agent or have been set aside by the Company in trust
in accordance with ‎Article 4 of this Contingent Convertible Securities Indenture;
provided, however, that at the time of such deposit or setting aside, and immediately thereafter, the foregoing provisions of this
‎Section 11.01 are complied with.

 

    35

     

    

Section 11.02. Provisions Solely to Define
Relative Rights. The provisions of this ‎Article 11 are and are intended solely for the purpose of defining the relative
rights of the Holders of the Contingent Convertible Securities of the series on the one hand and the Senior Creditors on the other
hand, as shall be defined in the supplemental indenture establishing the terms of the Contingent Convertible Securities of such
series. Nothing contained in this Article or elsewhere in this Contingent Convertible Securities Indenture or in such Contingent
Convertible Securities is intended to or shall (a) impair, as among the Company and the Holders of the Contingent Convertible Securities,
the obligation of the Company, which is absolute and unconditional, to pay to the holders of such claims the principal of and interest,
if any, on such Contingent Convertible Securities as and when the same shall become due and payable in accordance with their terms
and this Contingent Convertible Securities Indenture; or (b) affect the relative rights against the Company of the Holders of such
Contingent Convertible Securities; or (c) subject to the terms of the Contingent Convertible Securities and this Contingent Convertible
Securities Indenture, prevent the Trustee or the Holder of any Contingent Convertible Securities of the series from exercising
all remedies otherwise permitted by applicable law upon default under this Contingent Convertible Securities Indenture, subject
to the rights, if any, under this Article of the Senior Creditors to receive cash, property or securities otherwise payable or
deliverable to the Trustee or such holder.

 

Section 11.03. Trustee to Effectuate
Subordination. Each Holder of a Contingent Convertible Security by his acceptance thereof authorizes and directs the Trustee
on his behalf to take such action as may be necessary or appropriate to effectuate the subordination of the Contingent Convertible
Securities provided in this ‎Article 11 and appoints the Trustee his or her attorney-in-fact for any and all such purposes.

 

Section 11.04. No Waiver of Subordination
Provisions. No right of any present or future Senior Creditors to enforce subordination as herein provided shall at any time
in any way be prejudiced or impaired by any act or failure to act on the part of the Company or by any act or failure to act, in
good faith, by any such Senior Creditor or by any noncompliance by the Company with the terms, provisions and covenants of this
Contingent Convertible Securities Indenture, regardless of any knowledge thereof that any such Senior Creditor may have or be otherwise
charged with.

 

Section 11.05. Notice to Trustee.
The Company shall give prompt written notice to the Trustee of any fact known to the Company that would prohibit the making of
any payment of monies to or by the Trustee in respect of the Contingent Convertible Securities of the series. Notwithstanding the
provisions of this Article or any other provisions of this Contingent Convertible Securities Indenture, the Trustee shall not be
charged with knowledge of the existence of any facts that would prohibit the making of any payment of monies to or by the Trustee
in respect of such Contingent Convertible Securities unless and until the Trustee shall have received written notice thereof from
the Company or a Senior Creditor or from any trustee therefor or representative thereof; and before the receipt of any such written
notice by an officer of the Trustee, the Trustee shall be entitled in all respects to assume that no such facts exist; provided,
however, that if the Trustee shall not have received the notice provided for in this Section at least two (2) Business Days (or
any other period of time as agreed between the Company and the Trustee) prior to the date (i) upon which by the terms hereof any
money may become payable for any purpose (including, without limitation, the payment of the principal of and interest, if any,
on any Contingent Convertible Security) or (ii) U.S. dollars and/or U.S. Government Obligations are deposited in trust pursuant
to Article 4, anything herein contained to the contrary notwithstanding, then the Trustee shall have full power and authority to
receive such money and to apply the same to the purpose for which such money was received and shall not be affected by any notice
to the contrary that may be received by it within two (2) Business Days prior to such date.

 

The Trustee, subject to the provisions of
Article 6, shall be entitled to conclusively rely on the delivery to it of a written notice by a Person representing himself or
herself to be a Senior Creditor or a trustee therefor or representative thereof, to establish that such notice has been given by
a Senior Creditor, or a trustee or representative on behalf of any such Senior Creditor. In the event that the Trustee determines
in good faith that further evidence is required with respect to the right of any Person as a Senior Creditor to participate in
any payment or distribution pursuant to this Article, the Trustee may request such Person to furnish evidence to the reasonable
satisfaction of the Trustee as to the amount of claims held by such Person, and if such evidence is not furnished, the Trustee
may defer any payment to such Person pending judicial determination as to the right of such Person to receive such payment.

 

Section 11.06. Reliance on Judicial Order
or Certificate of Liquidating Agent. Upon any payment or distribution of assets of the Company referred to in this Article,
the Trustee and the Holders of the Contingent Convertible Securities of the series shall be entitled to rely upon (a) any order
or decree entered by any court in Mexico (but not elsewhere) of competent jurisdiction in which such insolvency, bankruptcy, receivership,
liquidation, reorganization, dissolution, winding-up or similar case or proceeding is pending or (b) a certificate of the trustee
in bankruptcy, liquidating trustee, custodian, receiver, assignee for the benefit of creditors, agent or other Person making such
payment or distribution, delivered to the Trustee or to the Holders, for the purpose of ascertaining the Persons entitled to participate
in such payment or distribution, for the purpose of ascertaining the Persons entitled to participate in such payment or distribution,
the Senior Creditors and other claims against the Company, the amount thereof or payable thereon, the amount or amounts paid or
distributed thereon and all other facts pertinent thereto or to this ‎Article 11.

 

Section 11.07. Trustee Not Fiduciary
for Senior Creditors. With respect to the Senior Creditors, the Trustee undertakes to perform or to observe only such of its
covenants and obligations as are specifically set forth in this Contingent Convertible Securities Indenture, and no implied covenants
or obligations with respect to the Senior Creditors shall be read into this Contingent Convertible Securities Indenture against
the Trustee. The Trustee shall not be deemed to owe any fiduciary duty to the Senior Creditors and shall not be liable to any such
holders if it shall in good faith mistakenly pay over or distribute to Holders of Contingent Convertible Securities of the series
or to the Company or to any other Person cash, property or securities to which any Senior Creditors shall be entitled by virtue
of this Article or otherwise.

 

    36

     

    

Section 11.08. Rights of Trustee as Senior
Creditor; Preservation of Trustee’s Rights. The Trustee in its individual capacity shall be entitled to all the rights
set forth in this Article with respect to any claims of Senior Creditors that may at any time be held by it, to the same extent
as any other Senior Creditor, and nothing in this Contingent Convertible Securities Indenture or the Trust Indenture Act shall
deprive the Trustee of any of its rights as such holder.

 

Nothing in this Article shall apply to claims
of, or payments to, the Trustee under or pursuant to ‎Section
5.05 or ‎Section 6.07.

 

Section 11.09. Article Applicable to
Paying Agents. At all times when a Paying Agent other than the Trustee shall have been appointed by the Company and be then
acting hereunder, the term “Trustee” as used in this Article shall in such case (unless the context otherwise requires)
be construed as extending to and including such Paying Agent within its meaning as fully for all intents and purposes as if such
Paying Agent were named in this Article in addition to or in place of the Trustee; provided, however, that ‎Section 11.08 shall
not apply to the Company or any Affiliate of the Company if it or such Affiliate acts as Paying Agent.

 

This instrument may be executed in any number
of counterparts, each of which so executed shall be deemed to be an original, but all such counterparts shall together constitute
but one and the same instrument.

 

    37

     

    

IN WITNESS WHEREOF, the Company and the
Trustee have caused this Contingent Convertible Securities Indenture to be duly executed, all as of the day and year first above
written.

 

	GRUPO FINANCIERO SANTANDER MÉXICO, S.A.B. DE C.V.
	 
	By:	 
	 	Name:
	 	Title: Chief Financial Officer

 

	THE BANK OF NEW YORK MELLON, as Trustee
	 
	By:	 
	 	Name:
	 	Title:

 

    38

     

    

En la Ciudad de México, a los     días del mes
de diciembre de 2016, ante la Comisión Nacional Bancaria y de Valores, representada por su Director General Adjunto de Autorizaciones
Bursátiles, el Licenciado León Ernesto Ubilla Suazo y su Director de Asuntos Jurídicos Bursátiles,
el Licenciado Gerardo Martín Villarino Campa, con fundamento en el artículo 30 de la Ley para Regular las Agrupaciones
Financieras, el artículo 64 de la Ley de Instituciones de Crédito, y en ejercicio de la facultad prevista en los
artículos 4, fracción XXVI de la Ley de la Comisión Nacional Bancaria y de Valores, 12, 26, fracción
III, 55 y 58 del Reglamento Interior de la Comisión Nacional Bancaria y de Valores, y 1, fracción V, y último
párrafo y 5, fracción III del Acuerdo por el que se adscriben orgánicamente las unidades administrativas de
la Comisión Nacional Bancaria y de Valores, comparecen en representación de Grupo Financiero Santander México,
S.A.B. de C.V. (“Grupo Financiero Santander México”), los señores              y               en su carácter
de apoderados, con el fin de hacer constar oportunamente ante la Comisión Nacional Bancaria y de Valores la emisión
de los títulos denominados “Valores Convertibles Contingentes (Contingent Convertible Securities)”,
en los términos de la presente acta de emisión (Indenture), suscrita el    día  de diciembre de 2016,
en la ciudad de Nueva York, Estados Unidos de América, entre Grupo Financiero Santander México y The Bank of New
York Mellon, y que se rige conforme a las Leyes del Estado de Nueva York, Estados Unidos de América.

 

La presente constancia no exime de los demás actos, permisos
o autorizaciones que conforme a la normatividad aplicable requiera de la Comisión Nacional Bancaria y de Valores, Grupo
Financiero Santander México.

 

	Grupo Financiero Santander México, S.A.B. de C.V.
	 
	 
	 
	Sr. Apoderado
	 
	 
	 
	Sr. Apoderado
	 
	 
	OTORGADA ANTE LA
	COMISIÓN NACIONAL BANCARIA Y DE VALORES

 

 

 

	
        Lic. León Ernesto Ubilla
Suazo

        Director General Adjunto
de Autorizaciones Bursátiles
	
        Lic. Gerardo Martín
Villarino Campa

        Director de Asuntos
Jurídicos Bursátiles

 

    39EX-4.1

 Exhibit 4.1 

Execution Version 
  

 
  

NANTHEALTH, INC. 
 AND 

U.S. BANK NATIONAL ASSOCIATION, 

as Trustee 
 INDENTURE 

Dated as of December 21, 2016 

5.50% Convertible Senior Notes due 2021 
  

 
  

 TABLE OF CONTENTS 

 
  

 

							
	 	 	 	  	PAGE	 
	 ARTICLE 1
	   

	 DEFINITIONS
	   

			
	Section 1.01.	 	 Definitions
	  	 	1	  
	Section 1.02.	 	 References to Interest
	  	 	13	  
	
	ARTICLE 2	  
	ISSUE, DESCRIPTION, EXECUTION, REGISTRATION AND EXCHANGE OF NOTES	  
			
	Section 2.01. 	 	 Designation and Amount
	  	 	14	  
	Section 2.02.	 	 Form of Notes
	  	 	14	  
	Section 2.03.	 	 Date and Denomination of Notes; Payments of Interest and Defaulted Amounts
	  	 	15	  
	Section 2.04.	 	 Execution, Authentication and Delivery of Notes
	  	 	16	  
	Section 2.05.	 	 Exchange and Registration of Transfer of Notes; Restrictions on Transfer;
Depositary
	  	 	17	  
	Section 2.06.	 	 Mutilated, Destroyed, Lost or Stolen Notes
	  	 	27	  
	Section 2.07.	 	 Temporary Notes
	  	 	28	  
	Section 2.08.	 	 Cancellation of Notes Paid, Converted, Etc.
	  	 	29	  
	Section 2.09.	 	 CUSIP Numbers
	  	 	29	  
	Section 2.10.	 	 Additional Notes; Repurchases
	  	 	29	  
	
	ARTICLE 3	  
	SATISFACTION AND DISCHARGE	  
			
	Section 3.01. 	 	 Satisfaction and Discharge
	  	 	30	  
	
	ARTICLE 4	  
	PARTICULAR COVENANTS OF THE COMPANY	  
			
	Section 4.01. 	 	 Payment of Principal and Interest
	  	 	30	  
	Section 4.02.	 	 Maintenance of Office or Agency
	  	 	30	  
	Section 4.03.	 	 Appointments to Fill Vacancies in Trustee’s Office
	  	 	31	  
	Section 4.04.	 	 Provisions as to Paying Agent
	  	 	31	  
	Section 4.05.	 	 Existence
	  	 	32	  
	Section 4.06.	 	 Rule 144A Information Requirement and Annual Reports
	  	 	32	  
	Section 4.07.	 	 Stay, Extension and Usury Laws
	  	 	34	  
	Section 4.08.	 	 Compliance Certificate; Statements as to Defaults
	  	 	35	  
	Section 4.09.	 	 Further Instruments and Acts
	  	 	35	  
	Section 4.10.	 	 Limitations on Affiliate Debt
	  	 	35	  

  
 i 

							
	
	 ARTICLE 5 

LISTS OF HOLDERS AND REPORTS BY THE
COMPANY AND THE TRUSTEE
	   

  

			
	Section 5.01. 	 	 Lists of Holders
	  	 	36	  
	Section 5.02.	 	 Preservation and Disclosure of Lists
	  	 	36	  
	
	 ARTICLE 6 

DEFAULTS AND REMEDIES
	   

  

			
	Section 6.01. 	 	 Events of Default
	  	 	36	  
	Section 6.02.	 	 Acceleration; Rescission and Annulment
	  	 	37	  
	Section 6.03.	 	 Additional Interest
	  	 	38	  
	Section 6.04.	 	 Payments of Notes on Default; Suit Therefor
	  	 	39	  
	Section 6.05.	 	 Application of Monies Collected by Trustee
	  	 	41	  
	Section 6.06.	 	 Proceedings by Holders
	  	 	41	  
	Section 6.07.	 	 Proceedings by Trustee
	  	 	42	  
	Section 6.08.	 	 Remedies Cumulative and Continuing
	  	 	42	  
	Section 6.09.	 	 Direction of Proceedings and Waiver of Defaults by Majority of Holders
	  	 	43	  
	Section 6.10.	 	 Notice of Defaults
	  	 	43	  
	Section 6.11.	 	 Undertaking to Pay Costs
	  	 	43	  
	
	 ARTICLE 7 

CONCERNING THE TRUSTEE
	   

  

			
	Section 7.01. 	 	 Duties and Responsibilities of Trustee
	  	 	44	  
	Section 7.02.	 	 Reliance on Documents, Opinions, Etc.
	  	 	46	  
	Section 7.03.	 	 No Responsibility for Recitals, Etc.
	  	 	47	  
	Section 7.04.	 	 Trustee, Paying Agents, Conversion Agents, Bid Solicitation Agent or Note Registrar May Own
Notes
	  	 	47	  
	Section 7.05.	 	 Monies and Shares of Common Stock to Be Held in Trust
	  	 	47	  
	Section 7.06.	 	 Compensation and Expenses of Trustee
	  	 	47	  
	Section 7.07.	 	 Officer’s Certificate and Opinion of Counsel as Evidence
	  	 	48	  
	Section 7.08.	 	 Eligibility of Trustee
	  	 	48	  
	Section 7.09.	 	 Resignation or Removal of Trustee
	  	 	49	  
	Section 7.10.	 	 Acceptance by Successor Trustee
	  	 	50	  
	Section 7.11.	 	 Succession by Merger, Etc.
	  	 	50	  
	Section 7.12.	 	 Trustee’s Application for Instructions from the Company
	  	 	51	  
	
	 ARTICLE 8 

CONCERNING THE HOLDERS
	   

  

			
	Section 8.01. 	 	 Action by Holders
	  	 	51	  
	Section 8.02.	 	 Proof of Execution by Holders
	  	 	51	  
	Section 8.03.	 	 Who Are Deemed Absolute Owners
	  	 	52	  
	Section 8.04.	 	 Company-Owned Notes Disregarded
	  	 	52	  
	Section 8.05.	 	 Revocation of Consents; Future Holders Bound
	  	 	52	  

  
 ii 

							
	
	 ARTICLE 9 

HOLDERS’ MEETINGS
	   

  

			
	Section 9.01. 	 	 Purpose of Meetings
	  	 	53	  
	Section 9.02.	 	 Call of Meetings by Trustee
	  	 	53	  
	Section 9.03.	 	 Call of Meetings by Company or Holders
	  	 	54	  
	Section 9.04.	 	 Qualifications for Voting
	  	 	54	  
	Section 9.05.	 	 Regulations
	  	 	54	  
	Section 9.06.	 	 Voting
	  	 	54	  
	Section 9.07.	 	 No Delay of Rights by Meeting
	  	 	55	  
	
	 ARTICLE 10

SUPPLEMENTAL INDENTURES
	   

  

			
	Section 10.01. 	 	 Supplemental Indentures Without Consent of Holders
	  	 	55	  
	Section 10.02.	 	 Supplemental Indentures with Consent of Holders
	  	 	56	  
	Section 10.03.	 	 Effect of Supplemental Indentures
	  	 	57	  
	Section 10.04.	 	 Notation on Notes
	  	 	57	  
	Section 10.05.	 	 Evidence of Compliance of Supplemental Indenture to Be Furnished Trustee
	  	 	57	  
	
	 ARTICLE 11 

CONSOLIDATION, MERGER, SALE, CONVEYANCE AND
LEASE
	   

  

			
	Section 11.01. 	 	 Company May Consolidate, Etc. on Certain Terms
	  	 	58	  
	Section 11.02.	 	 Successor Corporation to Be Substituted
	  	 	58	  
	Section 11.03.	 	 Opinion of Counsel to Be Given to Trustee
	  	 	59	  
	
	 ARTICLE 12

IMMUNITY OF INCORPORATORS, STOCKHOLDERS, OFFICERS AND
DIRECTORS
	   

  

			
	Section 12.01. 	 	 Indenture and Notes Solely Corporate Obligations
	  	 	59	  
	
	 ARTICLE 13 

RESERVED
	   

  

	
	 ARTICLE 14

CONVERSION OF NOTES
	   

  

			
	Section 14.01.	 	 Conversion Privilege
	  	 	60	  
	Section 14.02.	 	 Conversion Procedure; Settlement Upon Conversion
	  	 	64	  
	Section 14.03.	 	 Increased Conversion Rate Applicable to Certain Notes Surrendered in Connection with Make-Whole
Fundamental Changes
	  	 	68	  
	Section 14.04.	 	 Adjustment of Conversion Rate
	  	 	70	  
	Section 14.05.	 	 Adjustments of Prices
	  	 	80	  
	Section 14.06.	 	 Shares to Be Fully Paid
	  	 	80	  

  
 iii 

							
	Section 14.07.	 	 Effect of Recapitalizations, Reclassifications and Changes of the Common Stock
	  	 	81	  
	Section 14.08.	 	 Certain Covenants
	  	 	83	  
	Section 14.09.	 	 Responsibility of Trustee
	  	 	83	  
	Section 14.10.	 	 Notice to Holders Prior to Certain Actions
	  	 	84	  
	Section 14.11.	 	 Stockholder Rights Plans
	  	 	84	  
	Section 14.12.	 	 Exchange in Lieu of Conversion
	  	 	85	  
	
	 ARTICLE 15 

REPURCHASE OF NOTES AT OPTION OF
HOLDERS
	   

  

			
	Section 15.01. 	 	 [Intentionally Omitted]
	  	 	85	  
	Section 15.02.	 	 Repurchase at Option of Holders Upon a Fundamental Change
	  	 	85	  
	Section 15.03.	 	 Withdrawal of Fundamental Change Repurchase Notice
	  	 	88	  
	Section 15.04.	 	 Deposit of Fundamental Change Repurchase Price
	  	 	88	  
	Section 15.05.	 	 Covenant to Comply with Applicable Laws Upon Repurchase of Notes
	  	 	89	  
	
	 ARTICLE 16 

NO REDEMPTION
	   

  

			
	Section 16.01.	 	 No Redemption
	  	 	89	  
	
	 ARTICLE 17 

MISCELLANEOUS PROVISIONS
	   

  

			
	Section 17.01. 	 	 Provisions Binding on Company’s Successors
	  	 	90	  
	Section 17.02.	 	 Official Acts by Successor Corporation
	  	 	90	  
	Section 17.03.	 	 Addresses for Notices, Etc.
	  	 	90	  
	Section 17.04.	 	 Governing Law; Jurisdiction
	  	 	90	  
	Section 17.05. 	 	 Evidence of Compliance with Conditions Precedent; Certificates and Opinions of Counsel to
Trustee
	  	 	91	  
	Section 17.06. 	 	 Legal Holidays
	  	 	91	  
	Section 17.07. 	 	 No Security Interest Created
	  	 	92	  
	Section 17.08. 	 	 Benefits of Indenture
	  	 	92	  
	Section 17.09.	 	 Table of Contents, Headings, Etc.
	  	 	92	  
	Section 17.10. 	 	 Authenticating Agent
	  	 	92	  
	Section 17.11. 	 	 Execution in Counterparts
	  	 	93	  
	Section 17.12. 	 	 Severability
	  	 	93	  
	Section 17.13. 	 	 Waiver of Jury Trial
	  	 	93	  
	Section 17.14. 	 	 Force Majeure
	  	 	93	  
	Section 17.15. 	 	 Calculations
	  	 	94	  
	Section 17.16.	 	 USA PATRIOT Act
	  	 	94	  
	
	EXHIBIT	  
	 Exhibit A
	 	 Form of Note
	  	 	A-1	  

  
 iv 

 INDENTURE dated as of December 21, 2016 between NantHealth, Inc., a Delaware corporation, as
issuer (the “Company,” as more fully set forth in Section 1.01) and U.S. Bank National Association, a national banking association organized under the laws of the United States of America, as trustee (the
“Trustee,” as more fully set forth in Section 1.01). 
 W I T N E S S E T H: 

WHEREAS, for its lawful corporate purposes, the Company has duly authorized the issuance of its 5.50% Convertible Senior Notes due 2021 (the
“Notes”), initially in an aggregate principal amount not to exceed $100,000,000 (as increased by an amount equal to the aggregate principal amount of any additional Notes purchased by the Initial Purchasers pursuant to the exercise
of their option to purchase additional Notes as set forth in the Purchase Agreement), and in order to provide the terms and conditions upon which the Notes are to be authenticated, issued and delivered, the Company has duly authorized the execution
and delivery of this Indenture; 
 WHEREAS, the Form of Note, the certificate of authentication to be borne by each Note, the Form of Notice
of Conversion, the Form of Fundamental Change Repurchase Notice and the Form of Assignment and Transfer to be borne by the Notes are to be substantially in the forms hereinafter provided; and 

WHEREAS, all acts and things necessary to make the Notes, when executed by the Company and authenticated and delivered by the Trustee or a
duly authorized authenticating agent, as in this Indenture provided, the valid, binding and legal obligations of the Company, and this Indenture a valid agreement according to its terms, have been done and performed, and the execution of this
Indenture and the issuance hereunder of the Notes have in all respects been duly authorized. 
 NOW, THEREFORE, THIS INDENTURE WITNESSETH:

 That in order to declare the terms and conditions upon which the Notes are, and are to be, authenticated, issued and delivered, and in
consideration of the premises and of the purchase and acceptance of the Notes by the Holders thereof, the Company covenants and agrees with the Trustee for the equal and proportionate benefit of the respective Holders from time to time of the Notes
(except as otherwise provided below), as follows: 
 ARTICLE 1 

DEFINITIONS 

Section 1.01. Definitions. The terms defined in this Section 1.01 (except as herein otherwise expressly provided or
unless the context otherwise requires) for all purposes of this Indenture and of any indenture supplemental hereto shall have the respective meanings specified in this Section 1.01. The words “herein,” “hereof,”
“hereunder” and words of similar import refer to this Indenture as a whole and not to any particular Article, Section or other subdivision. The terms defined in this Article include the plural as well as the singular. 

 “Acceptable Subordination Terms” means, with respect to any Indebtedness, terms
of subordination that provide: 
 (a) upon a liquidation, bankruptcy, reorganization, insolvency, receivership or similar proceeding
relating to the Company or its property, or in connection with an assignment for the benefit of creditors or in any marshalling of the Company’s assets and liabilities, all obligations (including interest after the commencement of any
bankruptcy proceeding) in respect of the Notes and this Indenture shall be paid in full in cash or other payment satisfactory to the Holders before the holders of such Indebtedness are entitled to receive any payment or other distribution with
respect to such Indebtedness; 
 (b) no payment in respect of such Indebtedness may be made if (i) an Event of Default described in any
of Sections 6.01(a), (b) or (c) has occurred and is continuing, by acceleration or otherwise, until such Event of Default is cured or waived or the obligations in respect of the Notes are paid in full in cash or other payment satisfactory to
the Holders, or (ii) any other Event of Default has occurred and is continuing and the Trustee or Holders of at least 25% in aggregate principal amount of the Notes then outstanding has sent to the Company a notice of default (a “Payment
Blockage Notice”); provided that no more than one Payment Blockage Notice may be sent during any 360-day period and payments in respect of such Indebtedness may resume upon the earliest to
occur of (A) the date on which such Event of Default is cured or waived, (B) the obligations under the Notes and this Indenture are paid in full in cash or other payment satisfactory to the Holders, (C) the date that is 179 days after
the date on which the Payment Blockage Notice is received, and (D) the date the Payment Blockage Notice is rescinded; and 
 (c) if any
holder of such Indebtedness (or any agent, trustee or other representative thereof) receives payment that is prohibited by the subordination provisions, such holder (or agent, trustee or other representative) will hold the payment in trust for the
benefit of the Holders and upon written request of the Trustee or Holders of at least 25% in aggregate principal amount of the Notes then outstanding will deliver the amounts in trust to the Trustee for application to the obligations under the Notes
and this Indenture. 
 “Additional Interest” means all amounts, if any, payable pursuant to Section 4.06(d), Section
4.06(e) and Section 6.03, as applicable. 
 “Additional Shares” shall have the meaning specified in Section 14.03(a).

 “Affiliate” of any specified Person means any other Person directly or indirectly controlling or controlled by or under
direct or indirect common control with such specified Person. For the purposes of this definition, “control,” when used with respect to any specified Person means the power to direct or cause the direction of the management and policies of
such Person, directly or indirectly, whether through the ownership of voting securities, by contract or otherwise; and the terms “controlling” and “controlled” have meanings correlative to the foregoing. 

“Affiliate Debt” means any Indebtedness incurred by the Company or its Subsidiaries in favor of any Affiliate of the Company
or its Subsidiaries (other than intercompany Indebtedness between the Company and its Subsidiaries and other than any Notes held by Affiliates of the 

  
 2 

 
Company), including Indebtedness incurred under (i) that certain Amended and Restated Promissory Note dated May 9, 2016 by the Company in favor of Nant Capital, LLC (as amended,
restated or otherwise modified from time to time); and (ii) that certain Amended and Restated Promissory Note dated June 1, 2016 by the Company in favor of NantOmics, LLC (as amended, restated or otherwise modified from time to time). 

“Affiliate Note” means any Note initially issued by the Company to any Holder that, at the time of the acquisition by such
Holder of such Note, is an Affiliate of the Company. 
 “Affiliated Entity” means any of (i) Dr. Patrick
Soon-Shiong or his estate, heirs and lineal descendants, (ii) any trust, individual retirement account, or business entity (including any corporation, limited liability company, partnership, foundation or similar entity) for which
Dr. Patrick Soon-Shiong retains sole voting and dispositive power with respect to the Common Stock held by such trust, individual retirement account, or business entity and the trustees, legal representatives, beneficiaries and/or beneficial
owners of such trust, individual retirement account or business entity, (iii) any not-for-profit-entity where the acquisition of the Company’s Common Equity is
directed by Dr. Patrick Soon-Shiong and (iv) any entity wholly owned by Dr. Patrick Soon-Shiong or his estate. 

“Bid Solicitation Agent” means the Company or the Person appointed by the Company to solicit bids for the Trading Price of
the Notes in accordance with Section 14.01(b)(i). The Company shall initially act as the Bid Solicitation Agent. 
 “Board of
Directors” means the board of directors of the Company or a committee of such board duly authorized to act for it hereunder. 

“Board Resolution” means a copy of a resolution certified by the Secretary or an Assistant Secretary of the Company to have
been duly adopted by the Board of Directors, and to be in full force and effect on the date of such certification, and delivered to the Trustee. 

“Business Day” means, with respect to any Note, any day other than a Saturday, a Sunday or a day on which the Federal Reserve
Bank of New York is authorized or required by law or executive order to close or be closed. 
 “Capital Stock” means, for
any entity, any and all shares, interests, rights to purchase, warrants, options, participations or other equivalents of or interests in (however designated) stock issued by that entity. 

“Cash Settlement” shall have the meaning specified in Section 14.02(a). 

“Clause A Distribution” shall have the meaning specified in Section 14.04(c). 

“Clause B Distribution” shall have the meaning specified in Section 14.04(c). 

“Clause C Distribution” shall have the meaning specified in Section 14.04(c). 

“close of business” means 5:00 p.m. (New York City time). 

  
 3 

 “Combination Settlement” shall have the meaning specified in Section 14.02(a).

 “Commission” means the U.S. Securities and Exchange Commission. 

“Common Equity” of any Person means Capital Stock of such Person that is generally entitled (a) to vote in the election
of directors of such Person or (b) if such Person is not a corporation, to vote or otherwise participate in the selection of the governing body, partners, managers or others that will control the management or policies of such Person. 

“Common Stock” means the common stock of the Company, par value $0.0001 per share, at the date of this Indenture, subject to
Section 14.07. 
 “Common Stock Change Event” shall have the meaning specified in Section 14.07(a). 

“Company” shall have the meaning specified in the first paragraph of this Indenture, and subject to the provisions of Article
11, shall include its successors and assigns. 
 “Company Order” means a written order of the Company, signed by
(a) the Company’s Chief Executive Officer, President, Executive or Senior Vice President or any Vice President (whether or not designated by a number or numbers or word or words added before or after the title “Vice President”)
and (b) any such other Officer designated in clause (a) of this definition or the Company’s Treasurer or Assistant Treasurer or Secretary or any Assistant Secretary, and delivered to the Trustee. 

“Conversion Agent” shall have the meaning specified in Section 4.02. 

“Conversion Consideration” shall have the meaning specified in Section 14.12. 

“Conversion Date” shall have the meaning specified in Section 14.02(c). 

“Conversion Obligation” shall have the meaning specified in Section 14.01(a). 

“Conversion Price” means as of any time, $1,000, divided by the Conversion Rate as of such time. 

“Conversion Rate” shall have the meaning specified in Section 14.01(a). 

“Corporate Trust Office” means the designated office of the Trustee at which at any time this Indenture shall be
administered, which office at the date hereof is located at U.S. Bank National Association, 633 West Fifth Street, 24th Floor, Los Angeles, California 90071, Attention: P. Oswald (NantHealth, Inc.
5.50% Convertible Senior Notes due 2021), or such other address as the Trustee may designate from time to time by notice to the Holders and the Company, or the designated corporate trust office of any successor trustee (or such other address as such
successor trustee may designate from time to time by notice to the Holders and the Company). 
 “Custodian” means the
Trustee, as custodian for The Depository Trust Company, with respect to the Global Notes, or any successor entity thereto. 

  
 4 

 “Daily Conversion Value” means, for each of the 40 consecutive Trading Days
during the Observation Period, 2.5% of the product of (a) the Conversion Rate on such Trading Day and (b) the Daily VWAP for such Trading Day. 

“Daily Measurement Value” means the Specified Dollar Amount (if any), divided by 40. 

“Daily Settlement Amount,” for each of the 40 consecutive Trading Days during the Observation Period, shall consist of: 

(a) cash in an amount equal to the lesser of (i) the Daily Measurement Value and (ii) the Daily Conversion Value on
such Trading Day; and 
 (b) if the Daily Conversion Value on such Trading Day exceeds the Daily Measurement Value, a number
of shares of Common Stock equal to (i) the difference between the Daily Conversion Value and the Daily Measurement Value, divided by (ii) the Daily VWAP for such Trading Day. 

“Daily VWAP” means, for each of the 40 consecutive Trading Days during the relevant Observation Period (or for each of the 10
consecutive Trading Days in the valuation period for the Interest Make-Whole Payment), the per share volume-weighted average price as displayed under the heading “Bloomberg VWAP” on Bloomberg page “NH <equity> AQR” (or its
equivalent successor if such page is not available) in respect of the period from the scheduled open of trading until the scheduled close of trading of the primary trading session on such Trading Day (or if such volume-weighted average price is
unavailable, the market value of one share of the Common Stock on such Trading Day determined, using a volume-weighted average method, by a nationally recognized independent investment banking firm retained for this purpose by the Company). The
“Daily VWAP” shall be determined without regard to after-hours trading or any other trading outside of the regular trading session trading hours. 

“Default” means any event that is, or after notice or passage of time, or both, would be, an Event of Default. 

“Defaulted Amounts” means any amounts on any Note (including, without limitation, the Fundamental Change Repurchase Price,
principal and interest) that are payable but are not punctually paid or duly provided for. 
 “Depositary” means, with
respect to each Global Note, the Person specified in Section 2.05(c) as the Depositary with respect to such Notes, until a successor shall have been appointed and become such pursuant to the applicable provisions of this Indenture, and thereafter,
“Depositary” shall mean or include such successor. 
 “Distributed Property” shall have the meaning
specified in Section 14.04(c). 
 “Effective Date” shall have the meaning specified in Section 14.03(c), except that, as
used in Section 14.04 and Section 14.05, “Effective Date” means the first date on which shares of the Common Stock trade on the applicable exchange or in the applicable market, regular way, reflecting the relevant share
split or share combination, as applicable. 

  
 5 

 “Event of Default” shall have the meaning specified in Section 6.01. 

“Ex-Dividend Date” means the first date on which shares of the Common Stock trade on
the applicable exchange or in the applicable market, regular way, without the right to receive the issuance, dividend or distribution in question, from the Company or, if applicable, from the seller of Common Stock on such exchange or market (in the
form of due bills or otherwise) as determined by such exchange or market. 
 “Exchange Act” means the Securities Exchange
Act of 1934, as amended, and the rules and regulations promulgated thereunder. 
 “Exchange Election” shall have the
meaning specified in Section 14.12. 
 “Form of Assignment and Transfer” means the “Form of Assignment and
Transfer” attached as Attachment 3 to the Form of Note attached hereto as Exhibit A. 
 “Form of Fundamental Change Repurchase
Notice” means the “Form of Fundamental Change Repurchase Notice” attached as Attachment 2 to the Form of Note attached hereto as Exhibit A. 

“Form of Note” means the “Form of Note” attached hereto as Exhibit A. 

“Form of Notice of Conversion” means the “Form of Notice of Conversion” attached as Attachment 1 to the Form of
Note attached hereto as Exhibit A. 
 “Fundamental Change” shall be deemed to have occurred at the time after the Notes are
originally issued if any of the following occurs: 
 (a) a “person” or “group” within the meaning of
Section 13(d) of the Exchange Act, other than (A) any Affiliated Entity; provided that the Affiliated Entities do not collectively become the direct or indirect “beneficial owners,” as defined in
Rule 13d-3 under the Exchange Act, of Company’s Common Equity representing more than 65% of the voting power of Company’s Common Equity or (B) the Company, its direct or indirect Wholly Owned
Subsidiaries and the employee benefit plans of the Company and its direct or indirect Wholly Owned Subsidiaries, files a Schedule TO (or any successor schedule, form or report) or any schedule, form or report under the Exchange Act that discloses
that such person or group has become the direct or indirect “beneficial owner,” as defined in Rule 13d-3 under the Exchange Act, of the Company’s Common Equity representing more than 50% of
the voting power of the Company’s Common Equity; 
 (b) the consummation of (A) any recapitalization, reclassification
or change of the Common Stock (other than changes resulting from a subdivision or combination) as a result of which the Common Stock would be converted into, or exchanged for, stock, other securities, other property or assets; (B) any share
exchange, consolidation or merger of the Company pursuant to which the Common Stock will be converted into cash, securities or other property or assets; or (C) any sale, lease or other transfer in one

  
 6 

 
transaction or a series of transactions of all or substantially all of the consolidated assets of the Company and its Subsidiaries, taken as a whole, to any Person other than one of the
Company’s Wholly Owned Subsidiaries; provided, however, that a transaction described in clause (B) in which the holders of all classes of the Company’s Common Equity immediately prior to such transaction own, directly or indirectly,
more than 50% of all classes of Common Equity of the continuing or surviving corporation or transferee or the parent thereof immediately after such transaction in substantially the same proportions as such ownership immediately prior to such
transaction shall not be a Fundamental Change pursuant to this clause (b); 
 (c) the stockholders of the Company approve any
plan or proposal for the liquidation or dissolution of the Company; or 
 (d) the Common Stock (or other common stock
underlying the Notes) ceases to be listed or quoted on any of The New York Stock Exchange, The NASDAQ Global Select Market or The NASDAQ Global Market (or any of their respective successors); 

provided, however, that a transaction or transactions described in clause (a) or clause (b) above shall not constitute a Fundamental
Change, if at least 90% of the consideration received or to be received by holders of the Common Stock, excluding cash payments for fractional shares and cash payments made in respect of dissenters’ appraisal rights, in connection with such
transaction or transactions consists of shares of common stock that are listed or quoted on any of The New York Stock Exchange, The NASDAQ Global Select Market or The NASDAQ Global Market (or any of their respective successors) or will be so listed
or quoted when issued or exchanged in connection with such transaction or transactions and as a result of such transaction or transactions the Notes become convertible into such consideration, excluding cash payments for fractional shares and cash
payments made in respect of dissenters’ appraisal rights (subject to the provisions of Section 14.02(a)). If any transaction in which the Common Stock is replaced by securities of another entity occurs, following completion of any related
Make-Whole Fundamental Change Period (or, in the case of a transaction that would have been a Fundamental Change or a Make-Whole Fundamental Change but for the proviso immediately following clause (d) of the definition thereof, following the
effective date of such transaction), references to the Company in this definition shall instead be references to such other entity. 

“Fundamental Change Company Notice” shall have the meaning specified in Section 15.02(c). 

“Fundamental Change Repurchase Date” shall have the meaning specified in Section 15.02(a). 

“Fundamental Change Repurchase Notice” shall have the meaning specified in Section 15.02(b)(i). 

“Fundamental Change Repurchase Price” shall have the meaning specified in Section 15.02(a). 

  
 7 

 “given,” with respect to any notice to be given to a Holder pursuant to this
Indenture, shall mean notice (x) given to the Depositary (or its designee) pursuant to the standing instructions from the Depositary or its designee, including by electronic mail in accordance with accepted practices or procedures at the
Depositary (in the case of a Global Note) or (y) mailed to such Holder by first class mail, postage prepaid, at its address as it appears on the Note Register, in each case in accordance with Section 17.03. Notice so “given” shall be
deemed to include any notice to be “mailed” or “delivered,” as applicable, under this Indenture. 
 “Global
Note” shall have the meaning specified in Section 2.05(b). 
 “Holder,” as applied to any Note, or other similar
terms (but excluding the term “beneficial holder”), means any Person in whose name at the time a particular Note is registered on the Note Register. 

“Indebtedness” of any specified person means, without duplication, any indebtedness in respect of borrowed money or that is
evidenced by bonds, notes, debentures or similar instruments or letters of credit (or reimbursement agreements with respect thereto) or any guarantee by the specified person thereof. 

“Indenture” means this instrument as originally executed or, if amended or supplemented as herein provided, as so amended or
supplemented. 
 “Initial Purchasers” means J.P. Morgan Securities LLC, Jefferies LLC, Cowen and Company, LLC and Canaccord
Genuity Inc. 
 “Interest Make-Whole Payment” shall have the meaning specified in Section 14.01(c)(i). 

“Interest Payment Date” means each June 15 and December 15 of each year, beginning on June 15, 2017. 

“Last Reported Sale Price” of the Common Stock on any date means the closing sale price per share (or if no closing sale
price is reported, the average of the bid and ask prices or, if more than one in either case, the average of the average bid and the average ask prices) on that date as reported in composite transactions for the principal U.S. national or regional
securities exchange on which the Common Stock is traded. If the Common Stock is not listed for trading on a U.S. national or regional securities exchange on the relevant date, the “Last Reported Sale Price” shall be the last quoted
bid price per share for the Common Stock in the over-the-counter market on the relevant date as reported by OTC Markets Group Inc. or a similar organization. If the
Common Stock is not so quoted, the “Last Reported Sale Price” shall be the average of the mid-point of the last bid and last ask prices per share for the Common Stock on the relevant date from
each of at least three nationally recognized independent investment banking firms selected by the Company for this purpose. 

“Make-Whole Fundamental Change” means any transaction or event that constitutes a Fundamental Change (as defined above and
determined after giving effect to any exceptions to or exclusions from such definition, but without regard to the proviso in clause (b) of the definition thereof). 

  
 8 

 “Make-Whole Fundamental Change Period” shall have the meaning specified in
Section 14.03(a). 
 “Market Disruption Event” means, for the purposes of determining amounts due upon conversion (a)
a failure by the primary U.S. national or regional securities exchange or market on which the Common Stock is listed or admitted for trading to open for trading during its regular trading session or (b) the occurrence or existence prior to 1:00
p.m., New York City time, on any Scheduled Trading Day for the Common Stock for more than one half-hour period in the aggregate during regular trading hours of any suspension or limitation imposed on trading (by reason of movements in price
exceeding limits permitted by the relevant stock exchange or otherwise) in the Common Stock or in any options contracts or futures contracts relating to the Common Stock. 

“Maturity Date” means December 15, 2021. 

“Measurement Period” shall have the meaning specified in Section 14.01(b)(i). 

“Note” or “Notes” shall have the meaning specified in the first paragraph of the recitals of this Indenture.

 “Note Register” shall have the meaning specified in Section 2.05(a). 

“Note Registrar” shall have the meaning specified in Section 2.05(a). 

“Notice of Conversion” shall have the meaning specified in Section 14.02(b). 

“Observation Period” with respect to any Note surrendered for conversion means: (i) if the relevant Conversion Date occurs
prior to September 15, 2021, the 40 consecutive Trading Day period beginning on, and including, the second Trading Day immediately succeeding such Conversion Date; and (ii) if the relevant Conversion Date occurs on or after September 15,
2021, the 40 consecutive Trading Days beginning on, and including, the 42nd Scheduled Trading Day immediately preceding the Maturity Date. 

“Offering Memorandum” means the preliminary offering memorandum dated December 15, 2016, as supplemented by the related
pricing term sheet dated December 15, 2016, relating to the offering and sale of the Notes. 
 “Officer” means, with
respect to the Company, the President, the Chief Executive Officer, Chief Financial Officer, the Treasurer, the Secretary, any Executive or Senior Vice President or any Vice President (whether or not designated by a number or numbers or word or
words added before or after the title “Vice President”). 
 “Officer’s Certificate,” when used with respect
to the Company means a certificate that is delivered to the Trustee and that is signed by any Officer of the Company. Each such certificate shall include the statements provided for in Section 17.05 if and to the extent required by the
provisions of such Section. The Officer giving an Officer’s Certificate pursuant to Section 4.08 shall be the principal executive, financial or accounting officer of the Company. 

  
 9 

 “open of business” means 9:00 a.m. (New York City time). 

“Opinion of Counsel” means an opinion in writing signed by legal counsel, who may be an employee of or counsel to the Company
or other counsel reasonably acceptable to the Trustee, that is delivered to the Trustee. Each such opinion shall include the statements provided for in Section 17.05 if and to the extent required by the provisions of such Section 17.05 and
such opinion may contain customary qualifications and assumptions. 
 “outstanding,” when used with reference to Notes,
shall, subject to the provisions of Section 8.04, mean, as of any particular time, all Notes authenticated and delivered by the Trustee under this Indenture, except: 

(a) Notes theretofore canceled by the Trustee or accepted by the Trustee for cancellation; 

(b) Notes, or portions thereof, that have become due and payable and in respect of which monies in the necessary amount shall
have been deposited in trust with the Trustee or with any Paying Agent (other than the Company) or shall have been set aside and segregated in trust by the Company (if the Company shall act as its own Paying Agent); 

(c) Notes that have been paid pursuant to Section 2.06 or Notes in lieu of which, or in substitution for which, other
Notes shall have been authenticated and delivered pursuant to the terms of Section 2.06 unless proof satisfactory to the Trustee is presented that any such Notes are held by protected purchasers in due course (in which case such other Notes
shall not be deemed to be outstanding); 
 (d) Notes converted pursuant to Article 14 and required to be cancelled pursuant
to Section 2.08; and 
 (e) Notes repurchased by the Company pursuant to the penultimate sentence of Section 2.10.

 “Paying Agent” shall have the meaning specified in Section 4.02. 

“Person” means an individual, a corporation, a limited liability company, an association, a partnership, a joint venture, a
joint stock company, a trust, an unincorporated organization or a government or an agency or a political subdivision thereof. 

“Physical Notes” means permanent certificated Notes in registered form issued in denominations of $1,000 principal amount and
integral multiples thereof. 
 “Physical Settlement” shall have the meaning specified in Section 14.02(a). 

  
 10 

 “Predecessor Note” of any particular Note means every previous Note evidencing
all or a portion of the same debt as that evidenced by such particular Note; and, for the purposes of this definition, any Note authenticated and delivered under Section 2.06 in lieu of or in exchange for a mutilated, lost, destroyed or stolen
Note shall be deemed to evidence the same debt as the mutilated, lost, destroyed or stolen Note that it replaces. 
 “Purchase
Agreement” means that certain Purchase Agreement, dated as of December 15, 2016, among the Company and the Initial Purchasers. 

“Record Date” means, with respect to any dividend, distribution or other transaction or event in which the holders of Common
Stock (or other applicable security) have the right to receive any cash, securities or other property or in which the Common Stock (or such other security) is exchanged for or converted into any combination of cash, securities or other property, the
date fixed for determination of holders of the Common Stock (or such other security) entitled to receive such cash, securities or other property (whether such date is fixed by the Board of Directors, by statute, by contract or otherwise). 

“Reference Property” shall have the meaning specified in Section 14.07(a). 

“Regular Record Date,” with respect to any Interest Payment Date, means the June 1 or December 1 (whether or not
such day is a Business Day) immediately preceding the applicable June 15 or December 15 Interest Payment Date, respectively. 

“Resale Restriction Termination Date” shall have the meaning specified in Section 2.05(c). 

“Responsible Officer” means, when used with respect to the Trustee, any officer within the corporate trust department of the
Trustee, including any vice president, assistant vice president, assistant secretary, assistant treasurer, trust officer or any other officer of the Trustee who customarily performs functions similar to those performed by the Persons who at the time
shall be such officers, respectively, or to whom any corporate trust matter is referred because of such person’s knowledge of and familiarity with the particular subject and who, in each case, shall have direct responsibility for the
administration of this Indenture. 
 “Restricted Securities” shall have the meaning specified in Section 2.05(c). 

“Rule 144” means Rule 144 as promulgated under the Securities Act. 

“Rule 144A” means Rule 144A as promulgated under the Securities Act. 

“Scheduled Trading Day” means a day that is scheduled to be a Trading Day on the principal U.S. national or regional
securities exchange or market on which the Common Stock is listed or admitted for trading. If the Common Stock is not so listed or admitted for trading, “Scheduled Trading Day” means a Business Day. 

“Securities Act” means the Securities Act of 1933, as amended, and the rules and regulations promulgated thereunder. 

  
 11 

 “Settlement Amount” has the meaning specified in Section 14.02(a)(iv). 

“Settlement Method” means, with respect to any conversion of Notes, Physical Settlement, Cash Settlement or Combination
Settlement, as elected (or deemed to have been elected) by the Company. 
 “Settlement Notice” has the meaning specified in
Section 14.02(a)(iii). 
 “Significant Subsidiary” means a Subsidiary of the Company that meets the definition of
“significant subsidiary” in Article 1, Rule 1-02 of Regulation S-X under the Exchange Act; provided that, in the case of a Subsidiary of the Company
that meets the criteria of clause (3) of the definition thereof but not clause (1) or clause (2) of the definition thereof, such Subsidiary shall not be deemed to be a Significant Subsidiary unless such Subsidiary’s income from continuing
operations before income taxes, extraordinary items and cumulative effect of a change in accounting principle exclusive of amounts attributable to any non-controlling interests for the last completed fiscal
year prior to the date of such determination exceeds $5,000,000. 
 “Specified Dollar Amount” means the maximum cash amount
per $1,000 principal amount of Notes to be received upon conversion as specified in the Settlement Notice related to any converted Notes (or otherwise deemed specified pursuant to Section 14.02(a)(iii)). 

“Spin-Off” shall have the meaning specified in Section 14.04(c). 

“Stock Price” shall have the meaning specified in Section 14.03(c). 

“Subsidiary” means, with respect to any Person, any corporation, association, partnership or other business entity of which
more than 50% of the total voting power of shares of Capital Stock or other interests (including partnership interests) entitled (without regard to the occurrence of any contingency) to vote in the election of directors, managers, general partners
or trustees thereof is at the time owned or controlled, directly or indirectly, by (i) such Person; (ii) such Person and one or more Subsidiaries of such Person; or (iii) one or more Subsidiaries of such Person. 

“Successor Person” shall have the meaning specified in Section 11.01(a). 

“Trading Day” means a day on which (i) trading in the Common Stock (or other security for which a closing sale price must be
determined) generally occurs on The NASDAQ Global Select Market or, if the Common Stock (or such other security) is not then listed on The NASDAQ Global Select Market, on the principal other U.S. national or regional securities exchange on which the
Common Stock (or such other security) is then listed or, if the Common Stock (or such other security) is not then listed on a U.S. national or regional securities exchange, on the principal other market on which the Common Stock (or such other
security) is then traded and (ii) a Last Reported Sale Price for the Common Stock (or such other security) is available on such securities exchange or market; provided that if the Common Stock (or such other security) is not so listed or
traded, “Trading Day” means a Business Day; and provided, further, that for purposes of determining amounts due upon conversion only, “Trading Day” means a day on which (x) there is no Market
Disruption Event and (y) trading in the Common Stock generally 

  
 12 

 
occurs on The NASDAQ Global Select Market or, if the Common Stock is not then listed on The NASDAQ Global Select Market, on the principal other U.S. national or regional securities exchange on
which the Common Stock is then listed or, if the Common Stock is not then listed on a U.S. national or regional securities exchange, on the principal other market on which the Common Stock is then listed or admitted for trading, except that if the
Common Stock is not so listed or admitted for trading, “Trading Day” means a Business Day. 
 “Trading
Price” of the Notes on any date of determination means the average of the secondary market bid quotations obtained by the Bid Solicitation Agent for $5,000,000 principal amount of Notes at approximately 3:30 p.m., New York City time, on
such determination date from three independent nationally recognized securities dealers the Company selects for this purpose; provided that if three such bids cannot reasonably be obtained by the Bid Solicitation Agent but two such bids are
obtained, then the average of the two bids shall be used, and if only one such bid can reasonably be obtained by the Bid Solicitation Agent, then that one bid shall be used. If the Bid Solicitation Agent cannot reasonably obtain at least one bid for
$5,000,000 principal amount of Notes from a nationally recognized securities dealer selected by the Company on any determination date, then the Trading Price per $1,000 principal amount of Notes on such determination date shall be deemed to be less
than 98% of the product of the Last Reported Sale Price of the Common Stock and the Conversion Rate. 
 “transfer” shall
have the meaning specified in Section 2.05(c). 
 “Trigger Event” shall have the meaning specified in Section 14.04(c).

 “Trust Indenture Act” means the Trust Indenture Act of 1939, as amended, as it was in force at the date of execution of
this Indenture; provided, however, that in the event the Trust Indenture Act of 1939 is amended after the date hereof, the term “Trust Indenture Act” shall mean, to the extent required by such amendment, the Trust Indenture
Act of 1939, as so amended. 
 “Trustee” means the Person named as the “Trustee” in the first paragraph of
this Indenture until a successor trustee shall have become such pursuant to the applicable provisions of this Indenture, and thereafter “Trustee” shall mean or include each Person who is then a Trustee hereunder. 

“unit of Reference Property” shall have the meaning specified in Section 14.07(a). 

“Valuation Period” shall have the meaning specified in Section 14.04(c). 

“Wholly Owned Subsidiary” means, with respect to any Person, any Subsidiary of such Person, except that, solely for purposes
of this definition, the reference to “50%” in the definition of “Subsidiary” shall be deemed replaced by a reference to “100%”. 

Section 1.02. References to Interest. Unless the context otherwise requires, any reference to interest on, or in respect of, any
Note in this Indenture shall be deemed to include Additional Interest if, in such context, Additional Interest is, was or would be payable pursuant to any of Section 4.06(d), Section 4.06(e) and Section 6.03. Unless the context otherwise
requires, any express mention of Additional Interest in any provision hereof shall not be construed as excluding Additional Interest in those provisions hereof where such express mention is not made. 

  
 13 

 ARTICLE 2 

ISSUE, DESCRIPTION, EXECUTION, REGISTRATION AND
EXCHANGE OF NOTES 
 Section 2.01. Designation and Amount. The Notes shall be
designated as the “5.50% Convertible Senior Notes due 2021.” The aggregate principal amount of Notes that may be authenticated and delivered under this Indenture is initially limited to $100,000,000 (as increased by an amount equal to the
aggregate principal amount of any additional Notes purchased by the Initial Purchasers pursuant to the exercise of their option to purchase additional Notes as set forth in the Purchase Agreement), subject to Section 2.10 and except for Notes
authenticated and delivered upon registration or transfer of, or in exchange for, or in lieu of other Notes to the extent expressly permitted hereunder. 

Section 2.02. Form of Notes. The Notes and the Trustee’s certificate of authentication to be borne by such Notes shall be
substantially in the respective forms set forth in Exhibit A, the terms and provisions of which shall constitute, and are hereby expressly incorporated in and made a part of this Indenture. To the extent applicable, the Company and the Trustee, by
their execution and delivery of this Indenture, expressly agree to such terms and provisions and to be bound thereby. 
 The Notes (other
than Affiliate Notes) shall be issued initially in the form of one or more Global Notes; provided, that Affiliate Notes shall be issued initially in the form of one or more Physical Notes. Physical Notes so issued will be registered in such
names and authorized in such denominations as a Holder shall request, duly executed by the Company and authenticated by the Trustee as hereinafter provided. Subject to the additional requirements of Section 2.05(c)(v) with respect to any Affiliate
Note, upon the written request of any Holder, subject to the Notes meeting the eligibility requirements of the Depositary, any of such Holder’s Physical Notes may be exchanged for a beneficial interest in a Global Note, which shall (1) be
assigned a restricted or unrestricted CUSIP number, as applicable, (2) be registered in the name of the Depositary, (3) bear the legend required on a Global Note set forth in Exhibit A hereto and (4) be deposited on behalf of such Holder with the
Custodian, duly executed by the Company and authenticated by the Trustee as hereinafter provided. 
 Any Global Note may be endorsed with or
have incorporated in the text thereof such legends or recitals or changes not inconsistent with the provisions of this Indenture as may be required by the Custodian or the Depositary, or as may be required to comply with any applicable law or any
regulation thereunder or with the rules and regulations of any securities exchange or automated quotation system upon which the Notes may be listed or traded or designated for issuance or to conform with any usage with respect thereto, or to
indicate any special limitations or restrictions to which any particular Notes are subject. 
 Any of the Notes may have such letters,
numbers or other marks of identification and such notations, legends or endorsements as any Officer executing the same may approve (execution thereof to be conclusive evidence of such approval) and as are not inconsistent with

  
 14 

 
the provisions of this Indenture, or as may be required to comply with any law or with any rule or regulation made pursuant thereto or with any rule or regulation of any securities exchange or
automated quotation system on which the Notes may be listed or designated for issuance, or to conform to usage or to indicate any special limitations or restrictions to which any particular Notes are subject. 

Each Global Note or Physical Note, as applicable, shall represent such principal amount of the outstanding Notes as shall be specified therein
and shall provide that it shall represent the aggregate principal amount of outstanding Notes from time to time endorsed thereon and, in the case of a Global Note, that the aggregate principal amount of outstanding Notes represented thereby may from
time to time be increased or reduced to reflect repurchases, cancellations, conversions, transfers or exchanges permitted hereby. Any endorsement of a Global Note to reflect the amount of any increase or decrease in the amount of outstanding Notes
represented thereby shall be made by the Trustee or the Custodian, at the direction of the Trustee, in such manner and upon instructions given by the Holder of such Notes in accordance with this Indenture. Payment of principal (including the
Fundamental Change Repurchase Price, if applicable) of, and accrued and unpaid interest on, a Global Note shall be made to the Holder of such Note on the date of payment, unless a record date or other means of determining Holders eligible to receive
payment is provided for herein. 
 Section 2.03. Date and Denomination of Notes; Payments of Interest and Defaulted Amounts.
(a) The Notes shall be issuable in registered form without coupons in denominations of $1,000 principal amount and integral multiples in excess thereof. Each Note shall be dated the date of its authentication and shall bear interest from the
date specified on the face of such Note. Accrued interest on the Notes shall be computed on the basis of a 360-day year composed of twelve 30-day months and, for partial
months, on the basis of the number of days actually elapsed in a 30-day month. 
 (b) The Person in
whose name any Note (or its Predecessor Note) is registered on the Note Register at the close of business on any Regular Record Date with respect to any Interest Payment Date shall be entitled to receive the interest payable on such Interest Payment
Date. The principal amount of any Note (x) in the case of any Physical Note, shall be payable at the office or agency of the Company maintained by the Company for such purposes in the United States of America, which shall initially be the
Corporate Trust Office and (y) in the case of any Global Note, shall be payable by wire transfer of immediately available funds to the account of the Depositary or its nominee. The Company shall pay, or cause the Paying Agent to pay, interest
(i) on any Physical Notes (A) to Holders holding Physical Notes having an aggregate principal amount of $5,000,000 or less, by check mailed to the Holders of these Notes at their address as it appears in the Note Register and (B) to
Holders holding Physical Notes having an aggregate principal amount of more than $5,000,000, either by check mailed to each Holder or, upon application by such a Holder to the Note Registrar not later than the relevant Regular Record Date, by wire
transfer in immediately available funds to that Holder’s account within the United States if such Holder has provided the Company, the Trustee or the Paying Agent with the requisite information necessary to make such wire transfer, which
application shall remain in effect until the Holder notifies, in writing, the Note Registrar to the contrary or (ii) on any Global Note by wire transfer of immediately available funds to the account of the Depositary or its nominee. 

  
 15 

 (c) Any Defaulted Amounts shall forthwith cease to be payable to the Holder on the relevant
payment date but shall accrue interest per annum at the rate borne by the Notes plus one percent, subject to the enforceability thereof under applicable law, from, and including, such relevant payment date, and such Defaulted Amounts together
with such interest thereon shall be paid by the Company, at its election in each case, as provided in clause (i) or (ii) below: 

(i) The Company may elect to make payment of any Defaulted Amounts to the Persons in whose names the Notes (or their respective
Predecessor Notes) are registered at the close of business on a special record date for the payment of such Defaulted Amounts, which shall be fixed in the following manner. The Company shall notify the Trustee in writing of the amount of the
Defaulted Amounts proposed to be paid on each Note and the date of the proposed payment (which shall be not less than 25 days after the receipt by the Trustee of such notice, unless the Trustee shall consent to an earlier date), and at the same time
the Company shall deposit with the Trustee an amount of money equal to the aggregate amount to be paid in respect of such Defaulted Amounts or shall make arrangements satisfactory to the Trustee for such deposit on or prior to the date of the
proposed payment, such money when deposited to be held in trust for the benefit of the Persons entitled to such Defaulted Amounts as in this clause provided. Thereupon the Company shall fix a special record date for the payment of such Defaulted
Amounts which shall be not more than 15 days and not less than 10 days prior to the date of the proposed payment, and not less than 10 days after the receipt by the Trustee of the notice of the proposed payment. The Company shall promptly notify the
Trustee in writing of such special record date and the Trustee, in the name and at the expense of the Company, shall give notice of the proposed payment of such Defaulted Amounts and the special record date therefor to each Holder at its address as
it appears in the Note Register, or by electronic means to the Depositary in the case of Global Notes, not less than 10 days prior to such special record date. Notice of the proposed payment of such Defaulted Amounts and the special record date
therefor having been so given, such Defaulted Amounts shall be paid to the Persons in whose names the Notes (or their respective Predecessor Notes) are registered at the close of business on such special record date and shall no longer be payable
pursuant to the following clause (ii) of this Section 2.03(c). 
 (ii) The Company may make payment of any Defaulted
Amounts in any other lawful manner not inconsistent with the requirements of any securities exchange or automated quotation system on which the Notes may be listed or designated for issuance, and upon such notice as may be required by such exchange
or automated quotation system, if, after written notice given by the Company to the Trustee of the proposed payment pursuant to this clause, such manner of payment shall be deemed practicable by the Trustee. 

Section 2.04. Execution, Authentication and Delivery of Notes. The Notes shall be signed in the name and on behalf of the
Company by the manual, facsimile, .pdf attachment or other electronically transmitted signature of its Chief Executive Officer, President, Chief Financial Officer, Treasurer, Secretary or any of its Executive or Senior Vice Presidents. 

  
 16 

 At any time and from time to time after the execution and delivery of this Indenture, the Company
may deliver Notes executed by the Company to the Trustee for authentication, together with a Company Order for the authentication and delivery of such Notes, and the Trustee in accordance with such Company Order shall authenticate and deliver such
Notes, without any further action by the Company hereunder, other than delivery of an Officer’s Certificate and Opinion of Counsel pursuant to Section 17.05. 

Only such Notes as shall bear thereon a certificate of authentication substantially in the form set forth on the Form of Note attached as
Exhibit A hereto, executed manually by an authorized signatory of the Trustee (or an authenticating agent appointed by the Trustee as provided by Section 17.10), shall be entitled to the benefits of this Indenture or be valid or obligatory for
any purpose. Such certificate by the Trustee (or such an authenticating agent) upon any Note executed by the Company shall be conclusive evidence that the Note so authenticated has been duly authenticated and delivered hereunder and that the Holder
is entitled to the benefits of this Indenture. 
 In case any Officer of the Company who shall have signed any of the Notes shall cease to
be such Officer before the Notes so signed shall have been authenticated and delivered by the Trustee, or disposed of by the Company, such Notes nevertheless may be authenticated and delivered or disposed of as though the person who signed such
Notes had not ceased to be such Officer of the Company; and any Note may be signed on behalf of the Company by such Persons as, at the actual date of the execution of such Note, shall be the Officers of the Company, although at the date of the
execution of this Indenture any such Person was not such an Officer. 
 Section 2.05. Exchange and Registration of Transfer of
Notes; Restrictions on Transfer; Depositary. (a) The Company shall cause to be kept at the Corporate Trust Office a register (the register maintained in such office or in any other office or agency of the Company designated pursuant to
Section 4.02, the “Note Register”) in which, subject to such reasonable regulations as it may prescribe, the Company shall provide for the registration of Notes and of transfers of Notes. Such register shall be in written form
or in any form capable of being converted into written form within a reasonable period of time. The Trustee is hereby initially appointed the “Note Registrar” for the purpose of registering Notes and transfers of Notes as herein
provided. The Company may appoint one or more co-Note Registrars in accordance with Section 4.02. 

Upon surrender for registration of transfer of any Note to the Note Registrar or any co-Note
Registrar, and satisfaction of the requirements for such transfer set forth in this Section 2.05, the Company shall execute, and the Trustee shall authenticate and deliver, in the name of the designated transferee or transferees, one or more
new Notes of any authorized denominations and of a like aggregate principal amount and bearing such restrictive legends as may be required by this Indenture. 

Notes may be exchanged for other Notes of any authorized denominations and of a like aggregate principal amount, upon surrender of the Notes
to be exchanged at any such office or agency maintained by the Company pursuant to Section 4.02. Whenever any Notes are so surrendered for exchange, the Company shall execute, and the Trustee shall authenticate and deliver, the Notes that the
Holder making the exchange is entitled to receive, bearing registration numbers not contemporaneously outstanding. 

  
 17 

 All Notes presented or surrendered for registration of transfer or for exchange, repurchase or
conversion shall (if so required by the Company, the Trustee, the Note Registrar or any co-Note Registrar) be duly endorsed, or be accompanied by a written instrument or instruments of transfer in form
satisfactory to the Company and duly executed, by the Holder thereof or its attorney-in-fact duly authorized in writing. Physical Notes must be surrendered to the
Trustee prior to any transfer or exchange. 
 No service charge shall be imposed by the Company, the Trustee, the Note Registrar, any co-Note Registrar or the Paying Agent for any exchange or registration of transfer of Notes, but the Company may require a Holder to pay a sum sufficient to cover any documentary, stamp or similar issue or transfer
tax required in connection therewith as a result of the name of the Holder of new Notes issued upon such exchange or registration of transfer being different from the name of the Holder of the old Notes surrendered for exchange or registration of
transfer. 
 None of the Company, the Trustee, the Note Registrar or any co-Note Registrar shall be
required to exchange or register a transfer of (i) any Notes surrendered for conversion or, if a portion of any Note is surrendered for conversion, such portion thereof surrendered for conversion or (ii) any Notes, or a portion of any
Note, surrendered for repurchase (and not withdrawn) in accordance with Article 15. 
 All Notes issued upon any registration of transfer or
exchange of Notes in accordance with this Indenture shall be the valid obligations of the Company, evidencing the same debt, and entitled to the same benefits under this Indenture as the Notes surrendered upon such registration of transfer or
exchange. 
 (b) To the extent, and for so long as, any Notes are eligible for book-entry settlement with the Depositary, unless otherwise
required by law, subject to Section 2.05(c)(iii) all Notes (other than Affiliate Notes, if any, which shall initially issued as Physical Notes) may be represented by one or more Notes in global form (each, a “Global Note”)
registered in the name of the Depositary or the nominee of the Depositary. Each Global Note shall bear the legend required on a Global Note set forth in Exhibit A hereto. The transfer and exchange of beneficial interests in a Global Note that does
not involve the issuance of a Physical Note shall be effected through the Depositary (but not the Trustee or the Custodian) in accordance with this Indenture (including the restrictions on transfer set forth herein) and the procedures of the
Depositary therefor. 
 (c) Every Note that bears or is required under this Section 2.05(c) to bear the legend set forth in this Section
2.05(c) (together with any Common Stock issued upon conversion of the Notes that is required to bear the legend set forth in Section 2.05(d), collectively, the “Restricted Securities”) shall be subject to the restrictions on
transfer set forth in this Section 2.05(c) (including the legend set forth below), unless such restrictions on transfer shall be eliminated or otherwise waived by written consent of the Company, and the Holder of each such Restricted Security, by
such Holder’s acceptance thereof, agrees to be bound by all such restrictions on transfer. As used in this Section 2.05(c) and Section 2.05(d), the term “transfer” encompasses any sale, pledge, transfer or other disposition
whatsoever of any Restricted Security. 

  
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 (i) Until the date (the “Resale Restriction Termination Date”)
that is the later of (1) the date that is one year after the last date of original issuance of the Notes, or such shorter period of time as permitted by Rule 144 or any successor provision thereto, and (2) such later date, if any, as may
be required by applicable law, any certificate evidencing such Note (and all securities issued in exchange therefor or substitution thereof, other than Common Stock, if any, issued upon conversion thereof, which shall bear the legend set forth in
Section 2.05(d), if applicable) shall bear a legend in substantially the following form (unless such Notes have been transferred pursuant to a registration statement that has become or been declared effective under the Securities Act and that
continues to be effective at the time of such transfer, or sold pursuant to the exemption from registration provided by Rule 144 or any similar provision then in force under the Securities Act, or unless otherwise agreed by the Company in writing,
with notice thereof to the Trustee): 
 THIS SECURITY AND THE COMMON STOCK, IF ANY, ISSUABLE UPON CONVERSION OF THIS SECURITY HAVE NOT BEEN
REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND MAY NOT BE OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED EXCEPT IN ACCORDANCE WITH THE FOLLOWING SENTENCE. BY ITS ACQUISITION HEREOF OR OF A
BENEFICIAL INTEREST HEREIN, THE ACQUIRER: 
 AGREES FOR THE BENEFIT OF NANTHEALTH, INC. (THE “COMPANY”) THAT
IT WILL NOT OFFER, SELL, PLEDGE OR OTHERWISE TRANSFER THIS SECURITY OR ANY BENEFICIAL INTEREST HEREIN PRIOR TO THE DATE THAT IS THE LATER OF (X) ONE YEAR AFTER THE LAST ORIGINAL ISSUE DATE HEREOF OR SUCH SHORTER PERIOD OF TIME AS PERMITTED BY
RULE 144 UNDER THE SECURITIES ACT OR ANY SUCCESSOR PROVISION THEREUNDER AND (Y) SUCH LATER DATE, IF ANY, AS MAY BE REQUIRED BY APPLICABLE LAW, EXCEPT: 

(A) TO THE COMPANY OR ANY SUBSIDIARY THEREOF, OR 

(B) PURSUANT TO A REGISTRATION STATEMENT WHICH HAS BECOME EFFECTIVE UNDER THE SECURITIES ACT, OR 

(C) WITHIN THE UNITED STATES, TO A QUALIFIED INSTITUTIONAL BUYER IN COMPLIANCE WITH RULE 144A UNDER THE SECURITIES ACT, OR 

(D) OUTSIDE THE UNITED STATES, THROUGH OFFERS AND SALES THAT OCCUR OUTSIDE THE UNITED STATES WITHIN THE MEANING OF REGULATION S
UNDER THE SECURITIES ACT, OR 
 (E) PURSUANT TO AN EXEMPTION FROM REGISTRATION PROVIDED BY RULE 144 UNDER THE SECURITIES ACT
OR ANY OTHER AVAILABLE EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT. 

  
 19 

 PRIOR TO THE REGISTRATION OF ANY TRANSFER IN ACCORDANCE WITH CLAUSE (E) ABOVE, THE COMPANY
AND THE TRUSTEE RESERVE THE RIGHT TO REQUIRE THE DELIVERY OF SUCH LEGAL OPINIONS, CERTIFICATIONS OR OTHER EVIDENCE AS MAY REASONABLY BE REQUIRED IN ORDER TO DETERMINE THAT THE PROPOSED TRANSFER IS BEING MADE IN COMPLIANCE WITH THE SECURITIES ACT AND
APPLICABLE STATE SECURITIES LAWS. NO REPRESENTATION IS MADE AS TO THE AVAILABILITY OF ANY EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT. 

No transfer of any Note prior to the Resale Restriction Termination Date will be registered by the Note Registrar unless the applicable box on
the Form of Assignment and Transfer has been checked. 
 (ii) Notwithstanding clause (i) above, each Affiliate Note (and
all securities issued in exchange therefor or substitution thereof, other than Common Stock, if any, issued upon conversion thereof, which shall bear the legend set forth in Section 2.05(d), if applicable) shall bear a legend in substantially the
following form (unless such Note has been transferred pursuant to a registration statement that has become or been declared effective under the Securities Act and that continues to be effective at the time of such transfer, or sold pursuant to the
exemption from registration provided by Rule 144 or any similar provision then in force under the Securities Act in a transaction that results in such security or underlying securities, as the case may be, no longer being “restricted
securities” (as defined in Rule 144 under the Securities Act), or unless otherwise agreed by the Company in writing, with notice thereof to the Trustee): 

THIS SECURITY AND THE COMMON STOCK, IF ANY, ISSUABLE UPON CONVERSION OF THIS SECURITY HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF
1933, AS AMENDED (THE “SECURITIES ACT”), AND MAY NOT BE OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED EXCEPT IN ACCORDANCE WITH THE FOLLOWING SENTENCE. BY ITS ACQUISITION HEREOF OR OF A BENEFICIAL INTEREST HEREIN, THE ACQUIRER:

 AGREES FOR THE BENEFIT OF NANTHEALTH, INC. (THE “COMPANY”) THAT IT WILL NOT OFFER, SELL, PLEDGE OR OTHERWISE TRANSFER
THIS SECURITY OR ANY BENEFICIAL INTEREST HEREIN PRIOR TO THE DATE THAT IS THE LATER OF (X) ONE YEAR AFTER THE LAST ORIGINAL ISSUE DATE HEREOF OR SUCH SHORTER PERIOD OF TIME AS PERMITTED BY RULE 144 UNDER THE SECURITIES ACT OR ANY SUCCESSOR
PROVISION THEREUNDER AND (Y) SUCH LATER DATE, IF ANY, AS MAY BE REQUIRED BY APPLICABLE LAW, EXCEPT: 
 (A) TO THE
COMPANY OR ANY SUBSIDIARY THEREOF, OR 
 (B) PURSUANT TO A REGISTRATION STATEMENT WHICH HAS BECOME EFFECTIVE UNDER THE
SECURITIES ACT, OR 
 (C) WITHIN THE UNITED STATES, TO A QUALIFIED INSTITUTIONAL BUYER IN COMPLIANCE WITH RULE 144A UNDER THE
SECURITIES ACT, OR 

  
 20 

 (D) OUTSIDE THE UNITED STATES, THROUGH OFFERS AND SALES THAT OCCUR OUTSIDE THE
UNITED STATES WITHIN THE MEANING OF REGULATION S UNDER THE SECURITIES ACT, OR 
 (E) PURSUANT TO AN EXEMPTION FROM
REGISTRATION PROVIDED BY RULE 144 UNDER THE SECURITIES ACT OR ANY OTHER AVAILABLE EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT. 

PRIOR TO THE REGISTRATION OF ANY TRANSFER IN ACCORDANCE WITH CLAUSE (E) ABOVE, THE COMPANY AND THE TRUSTEE RESERVE THE RIGHT TO REQUIRE
THE DELIVERY OF SUCH LEGAL OPINIONS, CERTIFICATIONS OR OTHER EVIDENCE AS MAY REASONABLY BE REQUIRED IN ORDER TO DETERMINE THAT THE PROPOSED TRANSFER IS BEING MADE IN COMPLIANCE WITH THE SECURITIES ACT AND APPLICABLE STATE SECURITIES LAWS. NO
REPRESENTATION IS MADE AS TO THE AVAILABILITY OF ANY EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT. 
 NO AFFILIATE (AS
DEFINED IN RULE 144 UNDER THE SECURITIES ACT) OF THE COMPANY OR PERSON THAT HAS BEEN AN AFFILIATE (AS DEFINED IN RULE 144 UNDER THE SECURITIES ACT) OF THE COMPANY DURING THE THREE IMMEDIATELY PRECEDING MONTHS MAY OFFER, SELL, PLEDGE OR OTHERWISE
TRANSFER THIS SECURITY OR A BENEFICIAL INTEREST HEREIN UNLESS PURSUANT TO A REGISTRATION STATEMENT WHICH HAS BECOME EFFECTIVE UNDER THE SECURITIES ACT OR PURSUANT TO AN EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT IN A
TRANSACTION THAT RESULTS IN SUCH SECURITY OR COMMON STOCK, AS THE CASE MAY BE, NO LONGER BEING A “RESTRICTED SECURITY” (AS DEFINED IN RULE 144 UNDER THE SECURITIES ACT). 

No transfer of any Affiliate Note will be registered by the Note Registrar unless the applicable box on the Form of Assignment and Transfer
has been checked. 
 (iii) Any Note (or security issued in exchange or substitution therefor) (A) as to which such
restrictions on transfer shall have expired in accordance with their terms, (B) that has been transferred pursuant to a registration statement that has become effective or been declared effective under the Securities Act and that continues to
be effective at the time of such transfer, or (C) that has been sold pursuant to the exemption from registration provided by Rule 144 or any similar provision then in force under the Securities Act, may, upon surrender of such Note for exchange
to the Note Registrar in accordance with the provisions of this Section 2.05, be exchanged for a new Note or Notes as a Physical Note or a Global Note, in either case, of like tenor and aggregate principal amount, which shall not bear the
restrictive legend required by this Section 2.05(c) and shall not be assigned a restricted CUSIP number. The Company shall be entitled to instruct the Custodian in writing to so surrender any Global Note as to which any of the conditions set forth
in clause (A) through (E) of Section 2.05(c)(i), and, upon such instruction, the Custodian shall so surrender such Global Note for exchange; and 

  
 21 

 
any new Global Note so exchanged therefor shall not bear the restrictive legend specified in this Section 2.05(c) and shall not be assigned a restricted CUSIP number. The Company shall promptly
notify the Trustee upon the occurrence of the Resale Restriction Termination Date and promptly after a registration statement, if any, with respect to the Notes or any Common Stock issued upon conversion of the Notes has been declared effective
under the Securities Act. The Company shall complete any exchange process for the removal of a restrictive legend required by this Section 2.05(c) in accordance with the applicable procedures of the Depositary. 

(iv) Notwithstanding any other provisions of this Indenture (other than the provisions set forth in this Section 2.05(c)), a
Global Note may not be transferred as a whole or in part except (i) by the Depositary to a nominee of the Depositary or by a nominee of the Depositary to the Depositary or another nominee of the Depositary or by the Depositary or any such
nominee to a successor Depositary or a nominee of such successor Depositary and (ii) for exchange of a Global Note or a portion thereof for one or more Physical Notes in accordance with the second immediately succeeding paragraph. 

The Depositary shall be a clearing agency registered under the Exchange Act. The Company initially appoints The Depository Trust Company to
act as Depositary with respect to each Global Note. Initially, each Global Note shall be issued to the Depositary, registered in the name of Cede & Co., as the nominee of the Depositary, and deposited with the Trustee as custodian for
Cede & Co. 
 If (A) the Depositary notifies the Company at any time that the Depositary is unwilling or unable to continue as
depositary for the Global Notes and a successor depositary is not appointed within 90 days, (B) the Depositary ceases to be registered as a clearing agency under the Exchange Act and a successor depositary is not appointed within 90 days or
(C) an Event of Default with respect to the Notes has occurred and is continuing and a beneficial owner of any Note requests that its beneficial interest therein be issued as a Physical Note, the Company shall execute, and the Trustee, upon
receipt of an Officer’s Certificate, an Opinion of Counsel and a Company Order for the authentication and delivery of Notes, shall authenticate and deliver (x) in the case of clause (C), a Physical Note to such beneficial owner in a
principal amount equal to the principal amount of such Note corresponding to such beneficial owner’s beneficial interest and (y) in the case of clause (A) or (B), Physical Notes to each beneficial owner of the related Global Notes (or
a portion thereof) in an aggregate principal amount equal to the aggregate principal amount of such Global Notes in exchange for such Global Notes, and upon delivery of the Global Notes to the Trustee such Global Notes shall be canceled. 

Physical Notes issued in exchange for all or a part of the Global Note pursuant to this Section 2.05(c) shall be registered in such names and
in such authorized denominations as the Depositary, pursuant to instructions from its direct or indirect participants or otherwise, or, in the case of clause (iii) of the immediately preceding paragraph, the relevant beneficial owner, shall
instruct the Trustee. Upon execution and authentication, the Trustee shall deliver such Physical Notes to the Persons in whose names such Physical Notes are so registered. 

At such time as all interests in a Global Note have been converted, canceled, repurchased or transferred, such Global Note shall be, upon
receipt thereof, canceled by the Trustee in 

  
 22 

 
accordance with standing procedures and existing instructions between the Depositary and the Custodian. At any time prior to such cancellation, if any interest in a Global Note is exchanged for
Physical Notes, converted, canceled, repurchased or transferred to a transferee who receives Physical Notes therefor or any Physical Note is exchanged or transferred for part of such Global Note, the principal amount of such Global Note shall, in
accordance with the standing procedures and instructions existing between the Depositary and the Custodian, be appropriately reduced or increased, as the case may be, and an endorsement shall be made on such Global Note, by the Trustee or the
Custodian, at the direction of the Trustee, to reflect such reduction or increase. 
 None of the Company, the Trustee or any agent of the
Company or the Trustee shall have any responsibility or liability for any aspect of the records relating to or payments made on account of beneficial ownership interests of a Global Note or maintaining, supervising or reviewing any records relating
to such beneficial ownership interests. 
 (v) After the Resale Restriction Termination Date, the Holder of an Affiliate Note
may exchange such Note for a beneficial interest in a Global Note or transfer such Affiliate Note to a Person who takes delivery thereof in the form of a beneficial interest in a Global Note only if the Trustee receives: (A) a Physical Note,
duly endorsed or accompanied by appropriate instruments of transfer in form satisfactory to the Company and the Trustee, (B) a certificate from such Holder certifying as follows: (1) in the case of a proposed exchange, such Holder
(x) is not an Affiliate of the Company and has not been an Affiliate of the Company during the three immediately preceding months, and (y) one year has elapsed since the later of the date the Affiliate Notes were acquired from the Company
or from an Affiliate of the Company, or (2) in the case of a proposed transfer, such representations as are necessary to establish (x) that such Holder’s proposed transfer of the Affiliate Note satisfies all applicable requirements
set forth in Rule 144 under the Securities Act or (y) that such Holder’s proposed transfer of Affiliate Notes was effected pursuant to an effective registration statement covering the resale of such Affiliate Note, (C) an Opinion of
Counsel in form and substance reasonably satisfactory to the Company to the effect that such proposed exchange or transfer is in compliance with the safe harbor contained in Rule 144 under the Securities Act and that the restrictions on transfer
contained on such Affiliate Note are no longer required in order to maintain compliance with such safe harbor or that such transfer was effected pursuant to an effective registration statement covering the sale of such Affiliate Note, and
(D) written instructions directing the Trustee to make, or to direct the Note Registrar to make, an adjustment to its books and records with respect to such Global Note to reflect an increase in the aggregate principal amount of the Notes
represented by the Global Note, such instructions to contain information regarding the Depositary account to be credited with such increase. Upon such transfer, and following delivery of an Officer’s Certificate from the Company and an Opinion
of Counsel, then the Trustee shall cancel such Physical Note and cause, or direct the Note Registrar to cause, in accordance with the standing instructions and procedures existing between the Depositary and the Note Registrar, the aggregate
principal amount of the Physical Note to be exchanged, and shall credit or cause to be credited to the account of the Person specified in such instructions a beneficial interest in the Global Note equal to the principal amount of the Physical Note
so cancelled. The Company shall issue and the Trustee shall authenticate, upon written order of the Company in the form of a Company Order, an Officer’s Certificate and an Opinion of Counsel, a new Global Note in the appropriate principal
amount. 

  
 23 

 (d) Common Stock Legend. 

(i) Until the Resale Restriction Termination Date, any stock certificate representing Common Stock issued upon conversion of a
Note shall bear a legend in substantially the following form (unless the Note or such Common Stock has been transferred pursuant to a registration statement that has become or been declared effective under the Securities Act and that continues to be
effective at the time of such transfer, or pursuant to the exemption from registration provided by Rule 144 or any similar provision then in force under the Securities Act, or such Common Stock has been issued upon conversion of a Note that has
transferred pursuant to a registration statement that has become or been declared effective under the Securities Act and that continues to be effective at the time of such transfer, or pursuant to the exemption from registration provided by Rule 144
or any similar provision then in force under the Securities Act, or unless otherwise agreed by the Company with written notice thereof to the Trustee and any transfer agent for the Common Stock): 

THIS SECURITY HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND MAY NOT BE
OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED EXCEPT IN ACCORDANCE WITH THE FOLLOWING SENTENCE. BY ITS ACQUISITION HEREOF OR OF A BENEFICIAL INTEREST HEREIN, THE ACQUIRER: 

AGREES FOR THE BENEFIT OF NANTHEALTH, INC. (THE “COMPANY”) THAT IT WILL NOT OFFER, SELL, PLEDGE OR OTHERWISE TRANSFER THIS
SECURITY OR ANY BENEFICIAL INTEREST HEREIN PRIOR TO THE DATE THAT IS THE LATER OF (X) ONE YEAR AFTER THE LAST ORIGINAL ISSUE DATE OF THE SERIES OF NOTES UPON THE CONVERSION OF WHICH THIS SECURITY WAS ISSUED OR SUCH SHORTER PERIOD OF TIME AS
PERMITTED BY RULE 144 UNDER THE SECURITIES ACT OR ANY SUCCESSOR PROVISION THEREUNDER AND (Y) SUCH LATER DATE, IF ANY, AS MAY BE REQUIRED BY APPLICABLE LAW, EXCEPT: 

(A) TO THE COMPANY OR ANY SUBSIDIARY THEREOF, OR 

(B) PURSUANT TO A REGISTRATION STATEMENT WHICH HAS BECOME EFFECTIVE UNDER THE SECURITIES ACT, OR 

(C) WITHIN THE UNITED STATES, TO A QUALIFIED INSTITUTIONAL BUYER IN COMPLIANCE WITH RULE 144A UNDER THE SECURITIES ACT, OR 

(D) OUTSIDE THE UNITED STATES, THROUGH OFFERS AND SALES THAT OCCUR OUTSIDE THE UNITED STATES WITHIN THE MEANING OF REGULATION S
UNDER THE SECURITIES ACT, OR 
 (E) PURSUANT TO AN EXEMPTION FROM REGISTRATION PROVIDED BY RULE 144 UNDER THE SECURITIES ACT
OR ANY OTHER AVAILABLE EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT. 

  
 24 

 PRIOR TO THE REGISTRATION OF ANY TRANSFER IN ACCORDANCE WITH CLAUSE (E) ABOVE, THE COMPANY
AND THE TRANSFER AGENT FOR THE COMPANY’S COMMON STOCK RESERVE THE RIGHT TO REQUIRE THE DELIVERY OF SUCH LEGAL OPINIONS, CERTIFICATIONS OR OTHER EVIDENCE AS MAY REASONABLY BE REQUIRED IN ORDER TO DETERMINE THAT THE PROPOSED TRANSFER IS BEING
MADE IN COMPLIANCE WITH THE SECURITIES ACT AND APPLICABLE STATE SECURITIES LAWS. NO REPRESENTATION IS MADE AS TO THE AVAILABILITY OF ANY EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT. 

(ii) Notwithstanding clause (i) above, any stock certificate representing Common Stock issued upon conversion of an
Affiliate Note shall bear a legend in substantially the following form (unless such Common Stock has been transferred pursuant to a registration statement that has become or been declared effective under the Securities Act and that continues to be
effective at the time of such transfer, or sold pursuant to the exemption from registration provided by Rule 144 or any similar provision then in force under the Securities Act in a transaction that results in such Common Stock no longer being a
“restricted security” (as defined in Rule 144 under the Securities Act), or unless otherwise agreed by the Company in writing, with notice thereof to the Trustee): 

THIS SECURITY HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND MAY NOT BE
OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED EXCEPT IN ACCORDANCE WITH THE FOLLOWING SENTENCE. BY ITS ACQUISITION HEREOF OR OF A BENEFICIAL INTEREST HEREIN, THE ACQUIRER: 

AGREES FOR THE BENEFIT OF NANTHEALTH, INC. (THE “COMPANY”) THAT IT WILL NOT OFFER, SELL, PLEDGE OR OTHERWISE TRANSFER THIS
SECURITY OR ANY BENEFICIAL INTEREST HEREIN PRIOR TO THE DATE THAT IS THE LATER OF (X) ONE YEAR AFTER THE LAST ORIGINAL ISSUE DATE OF THE SERIES OF NOTES UPON THE CONVERSION OF WHICH THIS SECURITY WAS ISSUED OR SUCH SHORTER PERIOD OF TIME AS
PERMITTED BY RULE 144 UNDER THE SECURITIES ACT OR ANY SUCCESSOR PROVISION THEREUNDER AND (Y) SUCH LATER DATE, IF ANY, AS MAY BE REQUIRED BY APPLICABLE LAW, EXCEPT: 

(A) TO THE COMPANY OR ANY SUBSIDIARY THEREOF, OR 

(B) PURSUANT TO A REGISTRATION STATEMENT WHICH HAS BECOME EFFECTIVE UNDER THE SECURITIES ACT, OR 

  
 25 

 (C) WITHIN THE UNITED STATES, TO A QUALIFIED INSTITUTIONAL BUYER IN COMPLIANCE
WITH RULE 144A UNDER THE SECURITIES ACT, OR 
 (D) OUTSIDE THE UNITED STATES, THROUGH OFFERS AND SALES THAT OCCUR OUTSIDE THE
UNITED STATES WITHIN THE MEANING OF REGULATION S UNDER THE SECURITIES ACT, OR 
 (E) PURSUANT TO AN EXEMPTION FROM
REGISTRATION PROVIDED BY RULE 144 UNDER THE SECURITIES ACT OR ANY OTHER AVAILABLE EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT. 

PRIOR TO THE REGISTRATION OF ANY TRANSFER IN ACCORDANCE WITH CLAUSE (E) ABOVE, THE COMPANY AND THE TRANSFER AGENT FOR THE COMPANY’S
COMMON STOCK RESERVE THE RIGHT TO REQUIRE THE DELIVERY OF SUCH LEGAL OPINIONS, CERTIFICATIONS OR OTHER EVIDENCE AS MAY REASONABLY BE REQUIRED IN ORDER TO DETERMINE THAT THE PROPOSED TRANSFER IS BEING MADE IN COMPLIANCE WITH THE SECURITIES ACT AND
APPLICABLE STATE SECURITIES LAWS. NO REPRESENTATION IS MADE AS TO THE AVAILABILITY OF ANY EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT. 

NO AFFILIATE (AS DEFINED IN RULE 144 UNDER THE SECURITIES ACT) OF THE COMPANY OR PERSON THAT HAS BEEN AN AFFILIATE (AS DEFINED IN RULE 144
UNDER THE SECURITIES ACT) OF THE COMPANY DURING THE THREE IMMEDIATELY PRECEDING MONTHS MAY OFFER, SELL, PLEDGE OR OTHERWISE TRANSFER THIS SECURITY OR A BENEFICIAL INTEREST HEREIN UNLESS PURSUANT TO A REGISTRATION STATEMENT WHICH HAS BECOME EFFECTIVE
UNDER THE SECURITIES ACT OR PURSUANT TO AN EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT IN A TRANSACTION THAT RESULTS IN SUCH SECURITY NO LONGER BEING A “RESTRICTED SECURITY” (AS DEFINED IN RULE 144 UNDER THE
SECURITIES ACT). 
 (iii) Any such Common Stock (A) as to which such restrictions on transfer shall have expired in
accordance with their terms, (B) that has been transferred pursuant to a registration statement that has become or been declared effective under the Securities Act and that continues to be effective at the time of such transfer, or
(C) that has been sold pursuant to the exemption from registration provided by Rule 144 or any similar provision then in force under the Securities Act, may, upon surrender of the certificates representing such shares of Common Stock for
exchange in accordance with the procedures of the transfer agent for the Common Stock, be exchanged for a new certificate or certificates for a like aggregate number of shares of Common Stock, which shall not bear the restrictive legend required by
this Section 2.05(d). 
 (e) Except as expressly set forth in Sections 2.05(c) and 2.05(d) with respect to Affiliate Notes (and shares of
Common Stock issuable upon conversion or exchange thereof), any Note or Common Stock issued upon the conversion or exchange of a Note that is purchased 

  
 26 

 
or owned by any Affiliate of the Company (or any Person who was an Affiliate of the Company at any time during the immediately preceding three months) may not be resold by such Affiliate (or such
Person, as the case may be) unless registered under the Securities Act or resold pursuant to an exemption from the registration requirements of the Securities Act in a transaction that results in such Note or Common Stock, as the case may be, no
longer being a “restricted security” (as defined under Rule 144). The Company shall cause any Note that is repurchased or owned by it to be surrendered to the Trustee for cancellation in accordance with Section 2.08. 

(f) Notwithstanding anything herein to the contrary, the Company may refuse to register any transfer of the Notes (or any shares of Common
Stock issuable upon conversion thereof) not made in accordance with the provisions of Regulation S of the Securities Act (§§ 230.901 through 230.905)), pursuant to registration under the Securities Act, or pursuant to an available
exemption from registration; provided, however, that if foreign law prevents the Company from refusing to register securities transfers, the Notes (or any shares of Common Stock issuable upon conversion thereof) include the restrictive
legends required by Section 2.05(c) and Section 2.05(d) to prevent any transfer of the Notes (or any shares of Common Stock issuable upon conversion thereof) not made in accordance with the provisions of this Regulation S of the Securities Act. 

(g) The Trustee shall have no obligation or duty to monitor, determine or inquire as to compliance with any restrictions on transfer imposed
under this Indenture or under applicable law with respect to any transfer of any interest in any Note (including any transfers between or among depositary participants or beneficial owners or holders of any Global Note) other than to require
delivery of such certificates and other documentation or evidence as are expressly required by the terms of this Indenture, and to examine the same to determine substantial compliance as to form with the express requirements thereof. 

(h) Neither the Trustee nor the Trustee in its capacity as Conversion Agent or Paying Agent shall have any responsibility or liability for any
actions taken or not taken by the Depositary. 
 Section 2.06. Mutilated, Destroyed, Lost or Stolen Notes. In case any Note
shall become mutilated or be destroyed, lost or stolen, the Company in its discretion may execute, and upon its written request the Trustee or an authenticating agent appointed by the Trustee shall authenticate and deliver, a new Note, bearing a
registration number not contemporaneously outstanding, in exchange and substitution for the mutilated Note, or in lieu of and in substitution for the Note so destroyed, lost or stolen. In every case the applicant for a substituted Note shall furnish
to the Company, to the Trustee and, if applicable, to such authenticating agent such security or indemnity as may be required by them to save each of them harmless from any loss, liability, cost or expense caused by or connected with such
substitution, and, in every case of destruction, loss or theft, the applicant shall also furnish to the Company, to the Trustee and, if applicable, to such authenticating agent evidence to their satisfaction of the destruction, loss or theft of such
Note and of the ownership thereof. 
 The Trustee or such authenticating agent may authenticate any such substituted Note and deliver the
same upon the receipt of such security or indemnity as the Trustee, the Company and, if applicable, such authenticating agent may require. No service charge shall be imposed by the 

  
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Company, the Trustee, the Note Registrar, any co-Note Registrar or the Paying Agent upon the issuance of any substitute Note, but the Company or the
Trustee may require a Holder to pay a sum sufficient to cover any documentary, stamp or similar issue or transfer tax required in connection therewith as a result of the name of the Holder of the new substitute Note being different from the name of
the Holder of the old Note that became mutilated or was destroyed, lost or stolen. In case any Note that has matured or is about to mature or has been surrendered for required repurchase or is about to be converted in accordance with Article 14
shall become mutilated or be destroyed, lost or stolen, the Company may, in its sole discretion, instead of issuing a substitute Note, pay or authorize the payment of or convert or authorize the conversion of the same (without surrender thereof
except in the case of a mutilated Note), as the case may be, if the applicant for such payment or conversion shall furnish to the Company, to the Trustee and, if applicable, to such authenticating agent such security or indemnity as may be required
by them to save each of them harmless for any loss, liability, cost or expense caused by or connected with such substitution, and, in every case of destruction, loss or theft, evidence satisfactory to the Company, the Trustee and, if applicable, any
Paying Agent or Conversion Agent evidence of their satisfaction of the destruction, loss or theft of such Note and of the ownership thereof. 

Every substitute Note issued pursuant to the provisions of this Section 2.06 by virtue of the fact that any Note is destroyed, lost or
stolen shall constitute an additional contractual obligation of the Company, whether or not the destroyed, lost or stolen Note shall be found at any time, and shall be entitled to all the benefits of (but shall be subject to all the limitations set
forth in) this Indenture equally and proportionately with any and all other Notes duly issued hereunder. To the extent permitted by law, all Notes shall be held and owned upon the express condition that the foregoing provisions are exclusive with
respect to the replacement, payment, conversion or repurchase of mutilated, destroyed, lost or stolen Notes and shall preclude any and all other rights or remedies notwithstanding any law or statute existing or hereafter enacted to the contrary with
respect to the replacement, payment, conversion or repurchase of negotiable instruments or other securities without their surrender. 

Section 2.07. Temporary Notes. Pending the preparation of Physical Notes, the Company may execute and the Trustee or an
authenticating agent appointed by the Trustee shall, upon written request of the Company, authenticate and deliver temporary Notes (printed or lithographed). Temporary Notes shall be issuable in any authorized denomination, and substantially in the
form of the Physical Notes but with such omissions, insertions and variations as may be appropriate for temporary Notes, all as may be determined by the Company. Every such temporary Note shall be executed by the Company and authenticated by the
Trustee or such authenticating agent upon the same conditions and in substantially the same manner, and with the same effect, as the Physical Notes. Without unreasonable delay, the Company shall execute and deliver to the Trustee or such
authenticating agent Physical Notes (other than any Global Note) and thereupon any or all temporary Notes (other than any Global Note) may be surrendered in exchange therefor, at each office or agency maintained by the Company pursuant to
Section 4.02 and the Trustee or such authenticating agent shall authenticate and deliver in exchange for such temporary Notes an equal aggregate principal amount of Physical Notes. Such exchange shall be made by the Company at its own expense
and without any charge therefor. Until so exchanged, the temporary Notes shall in all respects be entitled to the same benefits and subject to the same limitations under this Indenture as Physical Notes authenticated and delivered hereunder. 

  
 28 

 Section 2.08. Cancellation of Notes Paid, Converted, Etc. The Company shall cause all
Notes surrendered for the purpose of payment, repurchase, registration of transfer or exchange or conversion, if surrendered to any of the Company’s agents, Subsidiaries or Affiliates, to be delivered to the Trustee for cancellation. All Notes
delivered to the Trustee shall be canceled promptly by it in accordance with its customary procedures, and, except as expressly permitted by the provisions of this Indenture in the case of Notes surrendered for registration of transfer or exchange,
no Notes shall be authenticated in exchange thereof. The Trustee shall dispose of canceled Notes in accordance with its customary procedures and, after such disposition, shall deliver a certificate of such disposition to the Company, at the
Company’s written request in a Company Order. 
 Section 2.09. CUSIP Numbers. The Company in issuing the Notes may use
“CUSIP” numbers (if then generally in use), and, if so, the Trustee shall use “CUSIP” numbers in all notices issued to Holders as a convenience to such Holders; provided that any such notice may state that no
representation is made as to the correctness of such numbers either as printed on the Notes or on such notice and that reliance may be placed only on the other identification numbers printed on the Notes. The Company shall promptly notify the
Trustee in writing of any change in the “CUSIP” numbers. 
 Section 2.10. Additional Notes; Repurchases. The Company
may, without the consent of the Holders and notwithstanding Section 2.01, reopen this Indenture and issue additional Notes hereunder with the same terms and with the same CUSIP number as the Notes initially issued hereunder (other than
differences in the issue date, the issue price, interest accrued prior to the issue date of such additional Notes and, if applicable, restrictions on transfer in respect of such additional Notes) in an unlimited aggregate principal amount;
provided that if any such additional Notes are not fungible with the Notes initially issued hereunder for U.S. federal income tax purposes or securities law purposes, such additional Notes shall have one or more separate CUSIP numbers. Prior
to the issuance of any such additional Notes, the Company shall deliver to the Trustee a Company Order, an Officer’s Certificate and an Opinion of Counsel, such Officer’s Certificate and Opinion of Counsel to cover such matters, in
addition to those required by Section 17.05, as the Trustee shall reasonably request. 
 In addition, the Company may, to the extent
permitted by law, and directly or indirectly (regardless of whether such Notes are surrendered to the Company), repurchase Notes in the open market or otherwise, with or without notice to Holders, whether by the Company or its Subsidiaries or
through a private or public tender or exchange offer or through counterparties pursuant to private agreements, including by cash-settled swaps or other derivatives. The Company shall cause any Notes so repurchased (other than Notes repurchased
pursuant to cash-settled swaps or other derivatives) to be surrendered to the Trustee for cancellation in accordance with Section 2.08 and such Notes shall no longer be considered outstanding under this Indenture upon their cancellation. 

  
 29 

 ARTICLE 3 

SATISFACTION AND DISCHARGE 

Section 3.01. Satisfaction and Discharge. This Indenture and the Notes shall upon request of the Company contained in an
Officer’s Certificate cease to be of further effect, and the Trustee, at the expense of the Company, shall execute such instruments reasonably requested by the Company acknowledging satisfaction and discharge of this Indenture and the Notes,
when (a) (i) all Notes theretofore authenticated and delivered (other than Notes which have been destroyed, lost or stolen and which have been replaced, paid or converted as provided in Section 2.06) have been delivered to the Trustee for
cancellation; or (ii) the Company has deposited with the Trustee or delivered to Holders, as applicable, after the Notes have become due and payable, whether on the Maturity Date, any Fundamental Change Repurchase Date, upon conversion or
otherwise, cash or cash, shares of Common Stock or a combination thereof, as applicable, solely to satisfy the Company’s Conversion Obligation, sufficient to pay all of the outstanding Notes and all other sums due and payable under this
Indenture by the Company, including any Interest Make-Whole Payment, if applicable; and (b) the Company has delivered to the Trustee an Officer’s Certificate and an Opinion of Counsel, each stating that all conditions precedent herein
provided for relating to the satisfaction and discharge of this Indenture and the Notes have been complied with. Notwithstanding the satisfaction and discharge of this Indenture, the obligations of the Company to the Trustee under Section 7.06
shall survive. 
 ARTICLE 4 

PARTICULAR COVENANTS OF THE COMPANY 

Section 4.01. Payment of Principal and Interest. The Company covenants and agrees that it will pay or cause to be paid the
principal (including the Fundamental Change Repurchase Price, if applicable) of, and accrued and unpaid interest on, each of the Notes at the places, at the respective times and in the manner provided herein and in the Notes. 

Section 4.02. Maintenance of Office or Agency. The Company will maintain in the United States of America an office or agency where
the Notes may be surrendered for registration of transfer or exchange or for presentation for payment or repurchase (“Paying Agent”) or for conversion (“Conversion Agent”) and where notices and demands to or upon
the Company in respect of the Notes and this Indenture may be served. The Company will give prompt written notice to the Trustee of the location, and any change in the location, of such office or agency. If at any time the Company shall fail to
maintain any such required office or agency or shall fail to furnish the Trustee with the address thereof, such presentations, surrenders, notices and demands may be made or delivered to the Corporate Trust Office or the office or agency of the
Trustee in the United States of America so designated by the Trustee as a place where Notes may be presented for payment or for registration or transfer. 

The Company may also from time to time designate as co-Note Registrars one or more other offices or
agencies where the Notes may be presented or surrendered for any or all such purposes and may from time to time rescind such designations; provided that no such designation or rescission shall in any manner relieve the Company of its
obligation to maintain an office or 

  
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agency in the United States of America so designated by the Trustee for such purposes. The Company will give prompt written notice to the Trustee of any such designation or rescission and of any
change in the location of any such other office or agency. The terms “Paying Agent” and “Conversion Agent” include any such additional or other offices or agencies, as applicable. 

The Company hereby initially designates the Trustee as the Paying Agent, Note Registrar, Custodian and Conversion Agent and the Corporate
Trust Office as the office or agency in the United States of America where Notes may be surrendered for registration of transfer or exchange or for presentation for payment or repurchase or for conversion and where notices and demands to or upon the
Company in respect of the Notes and this Indenture may be delivered. 
 Section 4.03. Appointments to Fill Vacancies in
Trustee’s Office. The Company, whenever necessary to avoid or fill a vacancy in the office of Trustee, will appoint, in the manner provided in Section 7.09, a Trustee, so that there shall at all times be a Trustee
hereunder. 
 Section 4.04. Provisions as to Paying Agent. (a) If the Company shall appoint a Paying Agent other than the
Trustee, the Company will cause such Paying Agent to execute and deliver to the Trustee an instrument in which such agent shall agree with the Trustee, subject to the provisions of this Section 4.04: 

(i) that it will hold all sums held by it as such agent for the payment of the principal (including the Fundamental Change
Repurchase Price, if applicable) of, and accrued and unpaid interest on, the Notes in trust for the benefit of the Holders of the Notes; 

(ii) that it will give the Trustee prompt notice of any failure by the Company to make any payment of the principal (including
the Fundamental Change Repurchase Price, if applicable) of, and accrued and unpaid interest on, the Notes when the same shall be due and payable; and 

(iii) that at any time during the continuance of an Event of Default, upon request of the Trustee, it will forthwith pay to the
Trustee all sums so held in trust. 
 The Company shall, on or before each due date of the principal (including the Fundamental Change
Repurchase Price, if applicable) of, or accrued and unpaid interest on, the Notes, deposit with the Paying Agent a sum sufficient to pay such principal (including the Fundamental Change Repurchase Price, if applicable) or accrued and unpaid
interest, and (unless such Paying Agent is the Trustee) the Company will promptly notify in writing the Trustee of any failure to take such action; provided that if such deposit is made on the due date, such deposit must be received by the
Paying Agent by 11:00 a.m., New York City time, on such date. 
 (b) If the Company shall act as its own Paying Agent, it will, on or before
each due date of the principal (including the Fundamental Change Repurchase Price, if applicable) of, and accrued and unpaid interest on, the Notes, set aside, segregate and hold in trust for the benefit of the Holders of the Notes a sum sufficient
to pay such principal (including the Fundamental Change Repurchase Price, if applicable) and accrued and unpaid interest so becoming due and will promptly notify the Trustee in writing of any failure to take such action and of any failure by

  
 31 

 
the Company to make any payment of the principal (including the Fundamental Change Repurchase Price, if applicable) of, or accrued and unpaid interest on, the Notes when the same shall become due
and payable. 
 (c) Anything in this Section 4.04 to the contrary notwithstanding, the Company may, at any time, for the purpose of
obtaining a satisfaction and discharge of this Indenture, or for any other reason, pay, cause to be paid or deliver to the Trustee all sums or amounts held in trust by the Company or any Paying Agent hereunder as required by this Section 4.04,
such sums or amounts to be held by the Trustee upon the trusts herein contained and upon such payment or delivery by the Company or any Paying Agent to the Trustee, the Company or such Paying Agent shall be released from all further liability but
only with respect to such sums or amounts. 
 (d) Subject to applicable abandoned property laws, any money and shares of Common Stock
deposited with the Trustee or any Paying Agent, or then held by the Company, in trust for the payment of the principal (including the Fundamental Change Repurchase Price, if applicable) of, accrued and unpaid interest on and the consideration due
upon conversion of any Note and remaining unclaimed for two years (or as of any common law escheatment date) after such principal (including the Fundamental Change Repurchase Price, if applicable), interest or consideration due upon conversion has
become due and payable shall be paid to the Company on request of the Company contained in an Officer’s Certificate, or (if then held by the Company) shall be discharged from such trust; and the Holder of such Note shall thereafter, as an
unsecured general creditor, look only to the Company for payment thereof, and all liability of the Trustee or such Paying Agent with respect to such trust money and shares of Common Stock, and all liability of the Company as trustee thereof, shall
thereupon cease; provided, however, that the Trustee or such Paying Agent, before being required to make any such repayment, may (but shall not be obligated to) at the expense of the Company cause to be published once, in a newspaper
published in the English language, customarily published on each Business Day and of general circulation in The Borough of Manhattan, The City of New York, notice that such money and shares of Common Stock remain unclaimed and that, after a date
specified therein, which shall not be less than 30 days from the date of such publication, any unclaimed balance of such money and shares of Common Stock then remaining will be repaid or delivered to the Company. 

(e) Upon any Event of Default pursuant to Section 6.01(h) or (i), the Trustee shall automatically be the Paying Agent, if the Trustee is not
the Paying Agent at such time. 
 (f) In the event that the Paying Agent receives funds in advance of any due date, the Paying Agent shall
be entitled to invest such funds in the U.S. Bank Money Market Deposit Account or any substantially similar successor account, any earnings on which shall be for the account of the Company. 

Section 4.05. Existence. Subject to Article 11, the Company shall do or cause to be done all things necessary to preserve and keep
in full force and effect its corporate existence. 
 Section 4.06. Rule 144A Information Requirement and Annual Reports.
(a) At any time the Company is not subject to Section 13 or 15(d) of the Exchange Act, the Company shall, so long as any of the Notes or any shares of Common Stock issuable upon conversion thereof shall, at such time, constitute
“restricted securities” within the meaning of Rule 144(a)(3) under the 

  
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Securities Act, promptly provide to the Trustee and, upon written request, any Holder, beneficial owner or prospective purchaser of such Notes or any shares of Common Stock issuable upon
conversion of such Notes, the information required to be delivered pursuant to Rule 144A(d)(4) under the Securities Act to facilitate the resale of such Notes or shares of Common Stock pursuant to Rule 144A. The Company shall take such further
action as any Holder or beneficial owner of the Notes may reasonably request to the extent from time to time required to enable such Holder or beneficial owner to sell the Notes or any shares of Common Stock issuable upon conversion of the Notes in
accordance with Rule 144A, as such rule may be amended from time to time. 
 (b) The Company shall file with the Trustee, within 15 days
after the same are required to be filed with the Commission (giving effect to any grace period provided by Rule 12b-25 (or any successor rule) under the Exchange Act), copies of any documents or reports that
the Company is required to file with the Commission pursuant to Section 13 or 15(d) of the Exchange Act. Any such document or report that the Company files with the Commission via the Commission’s EDGAR system (or any successor thereto)
shall be deemed to be filed with the Trustee for purposes of this Section 4.06(b) at the time such documents are filed via the EDGAR system (or any successor thereto), it being understood that the Trustee shall not be responsible for determining
whether such filings have been made. Notwithstanding anything to the contrary, the Company shall in no event be required to file with, or otherwise provide or disclose to, the Trustee or any Holder any information for which the Company is requesting
(assuming such request has not been denied), or have received, confidential treatment with the Commission) 
 (c) Delivery of the reports,
information and documents described in subsection (b) above to the Trustee is for informational purposes only, and the information and the Trustee’s receipt of such shall not constitute constructive notice of any information contained
therein, or determinable from information contained therein, including the Company’s compliance with any of its covenants hereunder (as to which the Trustee is entitled to conclusively rely on an Officer’s Certificate). 

(d) With respect to the Notes (other than Affiliate Notes), if, at any time during the six-month
period beginning on, and including, the date that is six months after the last date of original issuance of the Notes, the Company fails to timely file any document or report that it is required to file with the Commission pursuant to
Section 13 or 15(d) of the Exchange Act, as applicable (after giving effect to all applicable grace periods thereunder and other than reports on Form 8-K), or the Notes are not otherwise freely tradable
by Holders other than the Company’s Affiliates or Holders that were the Company’s Affiliates at any time during the immediately preceding three months (as a result of restrictions pursuant to U.S. securities laws or the terms of this
Indenture or the Notes), the Company shall pay Additional Interest on the Notes (other than Affiliate Notes). Such Additional Interest shall accrue on the Notes (other than Affiliate Notes) at the rate of 0.50% per annum of the principal amount of
the Notes outstanding (other than Affiliate Notes) for each day during such period for which the Company’s failure to file has occurred and is continuing or the Notes are not otherwise freely tradable by Holders other than the Company’s
Affiliates (or Holders that have been the Company’s Affiliates at any time during the immediately preceding three months) without restrictions pursuant to U.S. securities laws or 

  
 33 

 
the terms of this Indenture or the Notes. As used in this Section 4.06(d), documents or reports that the Company is required to “file” with the Commission pursuant to Section 13 or
15(d) of the Exchange Act does not include documents or reports that the Company furnishes to the Commission pursuant to Section 13 or 15(d) of the Exchange Act. 

(e) If, and for so long as, the restrictive legend on the Notes (other than Affiliate Notes) specified in Section 2.05(c) has not been
removed, the Notes (other than Affiliate Notes) are assigned a restricted CUSIP or the Notes are not otherwise freely tradable by Holders other than the Company’s Affiliates or Holders that were the Company’s Affiliates at any time during
the immediately preceding three months (without restrictions pursuant to U.S. securities laws or the terms of this Indenture or the Notes) as of the 370th day after the last date of original issuance of the Notes, the Company shall pay Additional
Interest on the Notes (other than Affiliate Notes) at a rate equal to 0.50% per annum of the principal amount of Notes (other than Affiliate Notes) outstanding until the restrictive legend on the Notes has been removed in accordance with Section
2.05(c), the Notes (other than Affiliate Notes) are assigned an unrestricted CUSIP and the Notes are freely tradable by Holders other than the Company’s Affiliates (or Holders that were the Company’s Affiliates at any time during the
immediately preceding three months) without restrictions pursuant to U.S. securities laws or the terms of this Indenture or the Notes. 

(f) Additional Interest will be payable in arrears on each Interest Payment Date following accrual in the same manner as regular interest on
the Notes. 
 (g) Subject to the immediately succeeding sentence, the Additional Interest that is payable in accordance with Section 4.06(d)
or Section 4.06(e) shall be in addition to, and not in lieu of, any Additional Interest that may be payable as a result of the Company’s election pursuant to Section 6.03. However, in no event shall any Additional Interest that may accrue
as a result of the Company’s failure to comply with its obligations pursuant to Section 4.06(d), together with any Additional Interest payable at the Company’s election pursuant to Section 6.03 as the remedy for an Event of Default
relating to its failure to comply with its obligations as set forth in Section 4.06(b), accrue at a rate in excess of 0.50% per annum, regardless of the number of events or circumstances giving rise to the requirement to pay such Additional
Interest. 
 (h) If Additional Interest is payable by the Company pursuant to Section 4.06(d) or Section 4.06(e), the Company shall deliver
to the Trustee an Officer’s Certificate to that effect stating (i) the amount of such Additional Interest that is payable and (ii) the date on which such Additional Interest is payable. Unless and until a Responsible Officer of the
Trustee receives at the Corporate Trust Office such a certificate, the Trustee may assume without inquiry that no such Additional Interest is payable and the Trustee shall not have any duty to verify the Company’s calculation of Additional
Interest. If the Company has paid Additional Interest directly to the Persons entitled to it, the Company shall deliver to the Trustee an Officer’s Certificate setting forth the particulars of such payment. 

Section 4.07. Stay, Extension and Usury Laws. The Company covenants (to the extent that it may lawfully do so) that it shall not
at any time insist upon, plead, or in any manner whatsoever claim or take the benefit or advantage of, any stay, extension or usury law or other law that would prohibit or forgive the Company from paying all or any portion of the principal of or
interest on the Notes as contemplated herein, wherever enacted, now or at any time hereafter 

  
 34 

 
in force, or that may affect the covenants or the performance of this Indenture; and the Company (to the extent it may lawfully do so) hereby expressly waives all benefit or advantage of any such
law, and covenants that it will not, by resort to any such law, hinder, delay or impede the execution of any power herein granted to the Trustee, but will suffer and permit the execution of every such power as though no such law had been enacted.

 Section 4.08. Compliance Certificate; Statements as to Defaults. The Company shall deliver to the Trustee within 120 days
after the end of each fiscal year of the Company (beginning with the fiscal year ending on December 31, 2016) an Officer’s Certificate stating whether the signers thereof have knowledge of any Default, Event of Default or other failure by
the Company to comply with all conditions and covenants then required to be performed under this Indenture and, if so, specifying each Default, Event of Default or other such failure and the nature thereof. 

In addition, the Company shall deliver to the Trustee, as soon as possible, and in any event within 30 days after the occurrence of any Event
of Default or Default, an Officer’s Certificate setting forth the details of such Event of Default or Default, its status and the action that the Company is taking or proposing to take in respect thereof and the action that the Company is
taking or proposing to take in respect thereof. 
 Section 4.09. Further Instruments and Acts. Upon request of the Trustee, the
Company will execute and deliver such further instruments and do such further acts as may be reasonably necessary or proper to carry out more effectively the purposes of this Indenture. 

Section 4.10. Limitations on Affiliate Debt.  

(a) For so long as at least $25,000,000 principal amount of Notes are outstanding, the Company shall not, nor shall the Company permit any of
its existing or future Subsidiaries to create, assume or incur any Affiliate Debt; provided, however, that the Company may, and may permit any of its existing and future Subsidiaries to, incur Affiliate Debt if: 

(i) no Default or Event of Default shall have occurred and be continuing at the time of such incurrence or would occur as a
consequence of such incurrence; 
 (ii) such Indebtedness is unsecured and, by its terms, is expressly subordinated to the
Notes pursuant to Acceptable Subordination Terms; and 
 (iii) no principal of such Indebtedness is scheduled to mature (or
subject to mandatory repurchase or put rights) earlier than the date that is 181 days after the Maturity Date. 
 (b) For so long as at
least $25,000,000 principal amount of Notes are outstanding, the Company shall not, nor shall the Company permit any of its existing or future Subsidiaries to prepay any Affiliate Debt; provided that the Company may convert, or exchange, any
Affiliate Debt into or for shares of Common Stock or other junior securities and cash in lieu of fractional shares. 

  
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 This Section 4.10 shall cease to apply upon the occurrence of a Fundamental Change described
in clause (a) or (b) of the definition thereof. 
 ARTICLE 5 

LISTS OF HOLDERS AND REPORTS BY THE
COMPANY AND THE TRUSTEE 
 Section 5.01. Lists of Holders. The
Company covenants and agrees that it will furnish or cause to be furnished to the Trustee and the Paying Agent, semi-annually, not more than 15 days after each June 15 and December 15 in each year beginning with June 15, 2017, and at
such other times as the Trustee may request in writing, within 30 days after receipt by the Company of any such request (or such lesser time as the Trustee may reasonably request in order to enable it to timely provide any notice to be provided by
it hereunder), a list in such form as the Trustee may reasonably require of the names and addresses of the Holders as of a date not more than 15 days (or such other date as the Trustee may reasonably request in order to so provide any such notices)
prior to the time such information is furnished, except that no such list need be furnished so long as the Trustee is acting as Note Registrar. 

Section 5.02. Preservation and Disclosure of Lists. The Trustee shall preserve, in as current a form as is reasonably practicable,
all information as to the names and addresses of the Holders contained in the most recent list furnished to it as provided in Section 5.01 or maintained by the Trustee in its capacity as Note Registrar, if so acting. The Trustee may destroy any
list furnished to it as provided in Section 5.01 upon receipt of a new list so furnished. 
 ARTICLE 6 

DEFAULTS AND REMEDIES 

Section 6.01. Events of Default. Each of the following events shall be an “Event of Default” with respect to the
Notes: 
 (a) default in any payment of interest on any Note when due and payable, and the default continues for a period of 30 days; 

(b) default in the payment of principal of any Note when due and payable on the Maturity Date, upon any required repurchase, upon declaration
of acceleration or otherwise; 
 (c) failure by the Company to comply with its obligation to convert the Notes in accordance with this
Indenture upon exercise of a Holder’s conversion right, including the payment of any Interest Make-Whole Payment, and such failure continues for five Business Days; 

(d) failure by the Company to issue a Fundamental Change Company Notice in accordance with Section 15.02(c) or notice of a specified corporate
event in accordance with Section 14.01(b)(ii) or Section 14.01(b)(iii), in each case, when due; 
 (e) failure by the Company to comply with
its obligations under Article 11; 

  
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 (f) failure by the Company for 60 days after written notice from the Trustee or the Holders of at
least 25% in principal amount of the Notes then outstanding has been received by the Company to comply with any of its other agreements contained in the Notes or this Indenture; 

(g) default by the Company or any Significant Subsidiary of the Company with respect to any mortgage, agreement or other instrument under
which there may be outstanding, or by which there may be secured or evidenced, any indebtedness for money borrowed in excess of $17,500,000 (or its foreign currency equivalent) in the aggregate of the Company and/or any such Significant Subsidiary,
whether such indebtedness now exists or shall hereafter be created (i) resulting in such indebtedness becoming or being declared due and payable or (ii) constituting a failure to pay the principal of any such indebtedness when due and
payable at its stated maturity, upon required repurchase, upon declaration of acceleration or otherwise, and in the cases of clauses (i) and (ii), such acceleration shall not have been rescinded or annulled or such failure to pay or default
shall not have been cured or waived, or such indebtedness is not paid or discharged, as the case may be, within 30 days determined in accordance with Section 8.04; 

(h) the Company or any Significant Subsidiary shall commence a voluntary case or other proceeding seeking liquidation, reorganization or other
relief with respect to the Company or any such Significant Subsidiary or its debts under any bankruptcy, insolvency or other similar law now or hereafter in effect or seeking the appointment of a trustee, receiver, liquidator, custodian or other
similar official of the Company or any such Significant Subsidiary or any substantial part of its property, or shall consent to any such relief or to the appointment of or taking possession by any such official in an involuntary case or other
proceeding commenced against it, or shall make a general assignment for the benefit of creditors, or shall fail generally to pay its debts as they become due; or 

(i) an involuntary case or other proceeding shall be commenced against the Company or any Significant Subsidiary seeking liquidation,
reorganization or other relief with respect to the Company or such Significant Subsidiary or its debts under any bankruptcy, insolvency or other similar law now or hereafter in effect or seeking the appointment of a trustee, receiver, liquidator,
custodian or other similar official of the Company or such Significant Subsidiary or any substantial part of its property, and such involuntary case or other proceeding shall remain undismissed and unstayed for a period of 30 consecutive days. 

Section 6.02. Acceleration; Rescission and Annulment. If one or more Events of Default shall have occurred and be continuing
(whatever the reason for such Event of Default and whether it shall be voluntary or involuntary or be effected by operation of law or pursuant to any judgment, decree or order of any court or any order, rule or regulation of any administrative or
governmental body), then, and in each and every such case (other than an Event of Default specified in Section 6.01(h) or Section 6.01(i) with respect to the Company), unless the principal of all of the Notes shall have already become due and
payable, either the Trustee or the Holders of at least 25% in aggregate principal amount of the Notes then outstanding determined in accordance with Section 8.04, by notice in writing to the Company and the Trustee, may declare 100% of the
principal of, and accrued and unpaid interest on, all the Notes to be due and payable immediately, and upon any such declaration the same shall become and shall automatically be immediately due and payable, anything contained in this Indenture or in
the Notes to the contrary notwithstanding. If an Event of Default specified in Section 6.01(h) or Section 6.01(i) with 

  
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respect to the Company occurs and is continuing, 100% of the principal of, and accrued and unpaid interest, if any, on, all Notes shall become and shall automatically be immediately due and
payable. 
 The immediately preceding paragraph, however, is subject to the conditions that if, at any time after the principal of the Notes
shall have been so declared due and payable, and before any judgment or decree for the payment of the monies due shall have been obtained or entered as hereinafter provided, the Company shall pay or shall deposit with the Trustee a sum sufficient to
pay installments of accrued and unpaid interest upon all Notes and the principal of any and all Notes that shall have become due otherwise than by acceleration (with interest on overdue installments of accrued and unpaid interest to the extent that
payment of such interest is enforceable under applicable law, and on such principal at the rate borne by the Notes plus one percent at such time) and amounts due to the Trustee pursuant to Section 7.06, and if (1) rescission would
not conflict with any judgment or decree of a court of competent jurisdiction and (2) any and all existing Events of Default under this Indenture, other than the nonpayment of the principal of and accrued and unpaid interest, if any, on Notes
that shall have become due solely by such acceleration, shall have been cured or waived pursuant to Section 6.09, then and in every such case (except as provided in the immediately succeeding sentence) the Holders of a majority in aggregate
principal amount of the Notes then outstanding, by written notice to the Company and to the Trustee, may waive all Defaults or Events of Default with respect to the Notes and rescind and annul such declaration and its consequences and such Default
shall cease to exist, and any Event of Default arising therefrom shall be deemed to have been cured for every purpose of this Indenture; but no such waiver or rescission and annulment shall extend to or shall affect any subsequent Default or Event
of Default, or shall impair any right consequent thereon. Notwithstanding anything to the contrary herein, no such waiver or rescission and annulment shall extend to or shall affect any Default or Event of Default resulting from (i) the
nonpayment of the principal (including the Fundamental Change Repurchase Price, if applicable) of, or accrued and unpaid interest on, any Notes, (ii) a failure to repurchase any Notes when required or (iii) a failure to pay or deliver, as
the case may be, the consideration due upon conversion of the Notes. 
 Section 6.03. Additional Interest. Notwithstanding
anything in this Indenture or in the Notes to the contrary, to the extent the Company elects, the sole remedy for an Event of Default relating to the Company’s failure to comply with its obligations as set forth in Section 4.06(b) shall for the
first 180 days after the occurrence of such an Event of Default, consist exclusively of the right to receive Additional Interest on the Notes at a rate equal to (x) 0.25% per annum of the principal amount of the Notes outstanding for each day during
the first 90-day period on which such Event of Default is continuing and (y) 0.50% per annum of the principal amount of the Notes outstanding for each day from the 91st day until the 180th day following the
occurrence of such an Event of Default. Subject to the last paragraph of this Section 6.03, Additional Interest payable pursuant to this Section 6.03 shall be in addition to, not in lieu of, any Additional Interest payable pursuant to
Section 4.06(d) or Section 4.06(e). If the Company so elects, such Additional Interest shall be payable in the same manner and on the same dates as the stated interest payable on the Notes. On the 181st day after such Event of Default (if the Event
of Default relating to the Company’s failure to file is not cured or waived prior to such 181st day), the Notes shall be immediately subject to acceleration as provided in Section 6.02. 

  
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The provisions of this paragraph will not affect the rights of Holders of Notes in the event of the occurrence of any Event of Default other than the Company’s failure to comply with its
obligations as set forth in Section 4.06(b). In the event the Company does not elect to pay Additional Interest following an Event of Default in accordance with this Section 6.03 or the Company elected to make such payment but does not pay the
Additional Interest when due, the Notes shall be immediately subject to acceleration as provided in Section 6.02. 
 In order to elect
to pay Additional Interest as the sole remedy during the first 180 days after the occurrence of any Event of Default described in the immediately preceding paragraph, the Company must notify in writing all Holders of the Notes, the Trustee and the
Paying Agent of such election prior to the beginning of such 180-day period. Upon the failure to timely give such notice, the Notes shall be immediately subject to acceleration as provided in
Section 6.02. 
 In no event shall Additional Interest payable at the Company’s election as the remedy for an Event of Default
relating to its failure to comply with its obligations under Section 4.06(b) as set forth in this Section 6.03, together with any interest that may accrue as a result of the Company’s failure to comply with its obligations as described in
Section 4.06(d), accrue at a rate in excess of 0.50% per annum, regardless of the number of events or circumstances giving rise to the requirement to pay such Additional Interest. The Trustee shall not have any duty to verify the Company’s
calculation of Additional Interest. 
 Section 6.04. Payments of Notes on Default; Suit Therefor. If an Event of Default
described in clause (a) or (b) of Section 6.01 shall have occurred, the Company shall, upon demand of the Trustee, pay to the Trustee, for the benefit of the Holders of the Notes, the whole amount then due and payable on the Notes for
principal and interest, if any, with interest on any overdue principal and interest, if any, at the rate borne by the Notes plus one percent at such time, and, in addition thereto, such further amount as shall be sufficient to cover any
amounts due to the Trustee under Section 7.06. If the Company shall fail to pay such amounts forthwith upon such demand, the Trustee, in its own name and as trustee of an express trust, may institute a judicial proceeding for the collection of
the sums so due and unpaid, may prosecute such proceeding to judgment or final decree and may enforce the same against the Company or any other obligor upon the Notes and collect the moneys adjudged or decreed to be payable in the manner provided by
law out of the property of the Company or any other obligor upon the Notes, wherever situated. 
 In the event there shall be pending
proceedings for the bankruptcy or for the reorganization of the Company or any other obligor on the Notes under Title 11 of the United States Code, or any other applicable law, or in case a receiver, assignee or trustee in bankruptcy or
reorganization, liquidator, sequestrator or similar official shall have been appointed for or taken possession of the Company or such other obligor, the property of the Company or such other obligor, or in the event of any other judicial proceedings
relative to the Company or such other obligor upon the Notes, or to the creditors or property of the Company or such other obligor, the Trustee, irrespective of whether the principal of the Notes shall then be due and payable as therein expressed or
by declaration or otherwise and irrespective of whether the Trustee shall have made any demand pursuant to the provisions of this Section 6.04, shall be entitled and empowered, by intervention in such proceedings or otherwise, to file and prove
a claim or claims for the whole amount of principal and accrued and unpaid interest, if any, in 

  
 39 

 
respect of the Notes, and, in case of any judicial proceedings, to file such proofs of claim and other papers or documents and to take such other actions as it may deem necessary or advisable in
order to have the claims of the Trustee (including any claim for the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel) and of the Holders allowed in such judicial proceedings relative to the
Company or any other obligor on the Notes, its or their creditors, or its or their property, and to collect and receive any monies or other property payable or deliverable on any such claims, and to distribute the same after the deduction of any
amounts due to the Trustee under Section 7.06; and any receiver, assignee or trustee in bankruptcy or reorganization, liquidator, custodian or similar official is hereby authorized by each of the Holders to make such payments to the Trustee, as
administrative expenses, and, in the event that the Trustee shall consent to the making of such payments directly to the Holders, to pay to the Trustee any amount due it for reasonable compensation, expenses, advances and disbursements, including
agents and counsel fees, and including any other amounts due to the Trustee under Section 7.06, incurred by it up to the date of such distribution. To the extent that such payment of reasonable compensation, expenses, advances and disbursements
out of the estate in any such proceedings shall be denied for any reason, payment of the same shall be secured by a lien on, and shall be paid out of, any and all distributions, dividends, monies, securities and other property that the Holders of
the Notes may be entitled to receive in such proceedings, whether in liquidation or under any plan of reorganization or arrangement or otherwise. 

Nothing herein contained shall be deemed to authorize the Trustee to authorize or consent to or accept or adopt on behalf of any Holder any
plan of reorganization, arrangement, adjustment or composition affecting such Holder or the rights of any Holder thereof, or to authorize the Trustee to vote in respect of the claim of any Holder in any such proceeding. 

All rights of action and of asserting claims under this Indenture, or under any of the Notes, may be enforced by the Trustee without the
possession of any of the Notes, or the production thereof at any trial or other proceeding relative thereto, and any such suit or proceeding instituted by the Trustee shall be brought in its own name as trustee of an express trust, and any recovery
of judgment shall, after provision for the payment of the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel, be for the ratable benefit of the Holders of the Notes. 

In any proceedings brought by the Trustee (and in any proceedings involving the interpretation of any provision of this Indenture to which the
Trustee shall be a party) the Trustee shall be held to represent all the Holders of the Notes, and it shall not be necessary to make any Holders of the Notes parties to any such proceedings. 

In case the Trustee shall have proceeded to enforce any right under this Indenture and such proceedings shall have been discontinued or
abandoned because of any waiver pursuant to Section 6.09 or any rescission and annulment pursuant to Section 6.02 or for any other reason or shall have been determined adversely to the Trustee, then and in every such case the Company, the
Holders and the Trustee shall, subject to any determination in such proceeding, be restored respectively to their several positions and rights hereunder, and all rights, remedies and powers of the Company, the Holders and the Trustee shall continue
as though no such proceeding had been instituted. 

  
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 Section 6.05. Application of Monies Collected by Trustee. Any monies or property
collected by the Trustee pursuant to this Article 6 with respect to the Notes shall be applied in the following order, at the date or dates fixed by the Trustee for the distribution of such monies or property, upon presentation of the several Notes,
and stamping thereon the payment, if only partially paid, and upon surrender thereof, if fully paid: 
 First, to the payment of all
amounts due the Trustee (in any capacity hereunder) under Section 7.06; 
 Second, in case the principal of the outstanding
Notes shall not have become due and be unpaid, to the payment of interest on, and any cash due upon conversion of, the Notes in default in the order of the date due of the payments of such interest and cash due upon conversion, as the case may be,
with interest (to the extent that such interest has been collected by the Trustee) upon such overdue payments at the rate borne by the Notes at such time, such payments to be made ratably to the Persons entitled thereto; 

Third, in case the principal of the outstanding Notes shall have become due, by declaration or otherwise, and be unpaid to the payment
of the whole amount (including, if applicable, the payment of the Fundamental Change Repurchase Price and any cash due upon conversion) then owing and unpaid upon the Notes for principal and interest, if any, with interest on the overdue principal
and, to the extent that such interest has been collected by the Trustee, upon overdue installments of interest at the rate borne by the Notes at such time plus one percent, and in case such monies shall be insufficient to pay in full the
whole amounts so due and unpaid upon the Notes, then to the payment of such principal (including, if applicable, the Fundamental Change Repurchase Price and the cash due upon conversion) and interest without preference or priority of principal over
interest, or of interest over principal or of any installment of interest over any other installment of interest, or of any Note over any other Note, ratably to the aggregate of such principal (including, if applicable, the Fundamental Change
Repurchase Price and any cash due upon conversion) and accrued and unpaid interest; and 
 Fourth, to the payment of the remainder,
if any, to the Company. 
 Section 6.06. Proceedings by Holders. Except to enforce the right to receive payment of principal
(including, if applicable, the Fundamental Change Repurchase Price) or interest when due, or the right to receive payment or delivery of the consideration due upon conversion, no Holder of any Note shall have any right by virtue of or by availing of
any provision of this Indenture to institute any suit, action or proceeding in equity or at law upon or under or with respect to this Indenture, or for the appointment of a receiver, trustee, liquidator, custodian or other similar official, or for
any other remedy hereunder, unless: 
 (a) such Holder previously shall have given to the Trustee written notice of an Event of Default and
of the continuance thereof, as herein provided; 
 (b) Holders of at least 25% in aggregate principal amount of the Notes then outstanding
shall have made written request upon the Trustee to institute such action, suit or proceeding in its own name as Trustee hereunder; 

  
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 (c) such Holders shall have offered to the Trustee such security or indemnity reasonably
satisfactory to it against any loss, liability or expense to be incurred therein or thereby; 
 (d) the Trustee for 60 days after its
receipt of such notice, request and offer of such security or indemnity, shall have neglected or refused to institute any such action, suit or proceeding; and 

(e) no written direction that, in the opinion of the Trustee, is inconsistent with such written request shall have been given to the Trustee
by the Holders of a majority of the aggregate principal amount of the Notes then outstanding within such 60-day period pursuant to Section 6.09, 

it being understood and intended, and being expressly covenanted by the taker and Holder of every Note with every other taker and Holder and the Trustee that
no one or more Holders shall have any right in any manner whatever by virtue of or by availing of any provision of this Indenture to affect, disturb or prejudice the rights of any other Holder, or to obtain or seek to obtain priority over or
preference to any other such Holder, or to enforce any right under this Indenture, except in the manner herein provided and for the equal, ratable and common benefit of all Holders (except as otherwise provided herein). For the protection and
enforcement of this Section 6.06, each and every Holder and the Trustee shall be entitled to such relief as can be given either at law or in equity. 

Notwithstanding any other provision of this Indenture and any provision of any Note, the right of any Holder to receive payment or delivery,
as the case may be, of (x) the principal (including the Fundamental Change Repurchase Price, if applicable) of, (y) accrued and unpaid interest, if any, on, and (z) the consideration due upon conversion of, such Note, on or after the
respective due dates expressed or provided for in such Note or in this Indenture, or to institute suit for the enforcement of any such payment or delivery, as the case may be, on or after such respective dates against the Company shall not be
impaired or affected without the consent of such Holder. 
 Section 6.07. Proceedings by Trustee. In case of an Event of
Default, the Trustee may in its discretion proceed to protect and enforce the rights vested in it by this Indenture by such appropriate judicial proceedings as are necessary to protect and enforce any of such rights, either by suit in equity or by
action at law or by proceeding in bankruptcy or otherwise, whether for the specific enforcement of any covenant or agreement contained in this Indenture or in aid of the exercise of any power granted in this Indenture, or to enforce any other legal
or equitable right vested in the Trustee by this Indenture or by law. 
 Section 6.08. Remedies Cumulative and Continuing.
Except as provided in the last paragraph of Section 2.06, all powers and remedies given by this Article 6 to the Trustee or to the Holders shall, to the extent permitted by law, be deemed cumulative and not exclusive of any thereof or of any
other powers and remedies available to the Trustee or the Holders of the Notes, by judicial proceedings or otherwise, to enforce the performance or observance of the covenants and agreements contained in this Indenture, and no delay or omission of
the Trustee or of any Holder of any of the Notes to exercise any right or power accruing upon any Default or Event of Default shall impair any such right or power, or shall be construed to be a waiver of any such

  
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Default or Event of Default or any acquiescence therein; and, subject to the provisions of Section 6.06, every power and remedy given by this Article 6 or by law to the Trustee or to the
Holders may be exercised from time to time, and as often as shall be deemed expedient, by the Trustee or by the Holders. 

Section 6.09. Direction of Proceedings and Waiver of Defaults by Majority of Holders. Subject to the Trustee’s right to
receive security or indemnity from the relevant Holders as described herein, the Holders of a majority of the aggregate principal amount of the Notes at the time outstanding determined in accordance with Section 8.04 shall have the right to
direct the time, method and place of conducting any proceeding for any remedy available to the Trustee or exercising any trust or power conferred on the Trustee with respect to the Notes; provided, however, that (a) such direction
shall not be in conflict with any rule of law or with this Indenture, and (b) the Trustee may take any other action deemed proper by the Trustee that is not inconsistent with such direction. The Trustee may refuse to follow any direction that
it determines is in conflict with law, this Indenture, is unduly prejudicial to the rights of any other Holder or that would involve the Trustee in personal liability. The Holders of a majority in aggregate principal amount of the Notes at the time
outstanding determined in accordance with Section 8.04 may on behalf of the Holders of all of the Notes waive any past Default or Event of Default hereunder and its consequences except (i) a default in the payment of accrued and unpaid
interest, if any, on, or the principal (including any Fundamental Change Repurchase Price) of, the Notes when due that has not been cured pursuant to the provisions of Section 6.01, (ii) a failure by the Company to pay or deliver, as the case
may be, the consideration due upon conversion of the Notes or (iii) a default in respect of a covenant or provision hereof which under Article 10 cannot be modified or amended without the consent of each Holder of an outstanding Note affected.
Upon any such waiver the Company, the Trustee and the Holders of the Notes shall be restored to their former positions and rights hereunder; but no such waiver shall extend to any subsequent or other Default or Event of Default or impair any right
consequent thereon. Whenever any Default or Event of Default hereunder shall have been waived as permitted by this Section 6.09, said Default or Event of Default shall for all purposes of the Notes and this Indenture be deemed to have been
cured and to be not continuing; but no such waiver shall extend to any subsequent or other Default or Event of Default or impair any right consequent thereon. 

Section 6.10. Notice of Defaults. The Trustee shall send to all Holders as the names and addresses of such Holders appear upon the
Note Register (or, in the case of Global Notes, pursuant to the customary procedures of the Depositary) notice of all Defaults actually known to a Responsible Officer within 90 days after it occurs, unless such Defaults shall have been cured or
waived before the giving of such notice; provided that, except in the case of a Default in the payment of the principal of (including the Fundamental Change Repurchase Price, if applicable), or accrued and unpaid interest on, any of the Notes
or a Default in the payment or delivery of the consideration due upon conversion, the Trustee shall be protected in withholding such notice if and so long as the Trustee in good faith determines that the withholding of such notice is in the
interests of the Holders. 
 Section 6.11. Undertaking to Pay Costs. All parties to this Indenture agree, and each Holder of any
Note by its acceptance thereof shall be deemed to have agreed, that any court may, 

  
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in its discretion, require, in any suit for the enforcement of any right or remedy under this Indenture, or in any suit against the Trustee for any action taken or omitted by it as Trustee, the
filing by any party litigant in such suit of an undertaking to pay the costs of such suit and that such court may in its discretion assess reasonable costs, including reasonable attorneys’ fees and expenses, against any party litigant in such
suit, having due regard to the merits and good faith of the claims or defenses made by such party litigant; provided that the provisions of this Section 6.11 (to the extent permitted by law) shall not apply to any suit instituted by the
Trustee, to any suit instituted by any Holder, or group of Holders, holding in the aggregate more than 10% in principal amount of the Notes at the time outstanding determined in accordance with Section 8.04, or to any suit instituted by any
Holder for the enforcement of the payment of the principal of or accrued and unpaid interest, if any, on any Note (including, but not limited to, the Fundamental Change Repurchase Price, if applicable) on or after the due date expressed or provided
for in such Note or to any suit for the enforcement of the right to convert any Note, or receive the consideration due upon conversion, in accordance with the provisions of Article 14. 

ARTICLE 7 

CONCERNING THE TRUSTEE 

Section 7.01. Duties and Responsibilities of Trustee. The Trustee, prior to the occurrence of an Event of Default and after the
curing or waiver of all Events of Default that may have occurred, undertakes to perform such duties and only such duties as are specifically set forth in this Indenture. In the event an Event of Default has occurred and is continuing, the Trustee
shall exercise such of the rights and powers vested in it by this Indenture, and use the same degree of care and skill in its exercise, as a prudent person would exercise or use under the circumstances in the conduct of such person’s own
affairs; provided that if an Event of Default occurs and is continuing, the Trustee will be under no obligation to exercise any of the rights or powers under this Indenture at the request or direction of any of the Holders unless such Holders
have offered to the Trustee indemnity or security satisfactory to it against any loss, liability or expense that might be incurred by it in compliance with such request or direction. Prior to taking any action hereunder at the Company’s
instruction, the Trustee shall be entitled to indemnification by the Company satisfactory to the Trustee against any loss, liability or expense caused by taking or not taking such action. 

No provision of this Indenture shall be construed to relieve the Trustee from liability for its own grossly negligent action, its own grossly
negligent failure to act or its own willful misconduct, except that: 
 (a) prior to the occurrence of an Event of Default and after the
curing or waiving of all Events of Default that may have occurred: 
 (i) the duties and obligations of the Trustee shall be
determined solely by the express provisions of this Indenture, and the Trustee shall not be liable except for the performance of such duties and obligations as are specifically set forth in this Indenture and no implied covenants or obligations
shall be read into this Indenture against the Trustee; and 
 (ii) in the absence of bad faith and willful misconduct on the
part of the Trustee, the Trustee may conclusively rely, as to the truth of the statements and the correctness of the opinions expressed therein, upon any certificates or opinions furnished to the Trustee and conforming to the requirements of this
Indenture; but, in the case of any such certificates or opinions that by any provisions hereof are specifically required to be furnished to the Trustee, the Trustee shall be under a duty to examine the same to determine whether or not they conform
to the requirements of this Indenture (but need not confirm or investigate the accuracy of any mathematical calculations or other facts stated therein); 

  
 44 

 (b) the Trustee shall not be liable for any error of judgment made in good faith by a Responsible
Officer or Officers of the Trustee, unless it shall be proved that the Trustee was grossly negligent in ascertaining the pertinent facts; 

(c) the Trustee shall not be liable with respect to any action taken or omitted to be taken by it in good faith in accordance with the
direction of the Holders of not less than a majority of the aggregate principal amount of the Notes at the time outstanding determined as provided in Section 8.04 relating to the time, method and place of conducting any proceeding for any
remedy available to the Trustee, or exercising any trust or power conferred upon the Trustee, under this Indenture; 
 (d) whether or not
therein provided, every provision of this Indenture relating to the conduct or affecting the liability of, or affording protection to, the Trustee shall be subject to the provisions of this Section; 

(e) the Trustee shall not be liable in respect of any payment (as to the correctness of amount, entitlement to receive or any other matters
relating to payment) or notice effected by the Company or any Paying Agent or any records maintained by any co-Note Registrar with respect to the Notes; 

(f) if any party fails to deliver a notice relating to an event the fact of which, pursuant to this Indenture, requires notice to be sent to
the Trustee, the Trustee may conclusively rely on its failure to receive such notice as reason to act as if no such event occurred, unless a Responsible Officer of the Trustee had actual knowledge of such event; 

(g) other than as provided in Section 4.04(e), in the absence of written investment direction from the Company, all cash received by the
Trustee shall be placed in a non-interest bearing trust account, and in no event shall the Trustee be liable for the selection of investments or for investment losses incurred thereon or for losses incurred as
a result of the liquidation of any such investment prior to its maturity date or the failure of the party directing such investments prior to its maturity date or the failure of the party directing such investment to provide timely written
investment direction, and the Trustee shall have no obligation to invest or reinvest any amounts held hereunder in the absence of such written investment direction from the Company; and 

(h) in the event that the Trustee is also acting as Custodian, Note Registrar, Paying Agent, Conversion Agent, Bid Solicitation Agent or
transfer agent hereunder, the rights and 

  
 45 

 
protections afforded to the Trustee pursuant to this Article 7 shall also be afforded to such Custodian, Note Registrar, Paying Agent, Conversion Agent, Bid Solicitation Agent or transfer agent.

 None of the provisions contained in this Indenture shall require the Trustee to expend or risk its own funds or otherwise incur personal
financial liability in the performance of any of its duties or in the exercise of any of its rights or powers. 
 The Trustee shall not be
required to give any bond or surety in respect of the performance of its powers or duties hereunder. 
 Section 7.02. Reliance on
Documents, Opinions, Etc. Except as otherwise provided in Section 7.01: 
 (a) the Trustee may conclusively rely and shall be fully
protected in acting upon any resolution, certificate, statement, instrument, opinion, report, notice, request, consent, order, bond, note, coupon or other paper or document believed by it in good faith to be genuine and to have been signed or
presented by the proper party or parties; 
 (b) any request, direction, order or demand of the Company mentioned herein shall be
sufficiently evidenced by an Officer’s Certificate (unless other evidence in respect thereof be herein specifically prescribed); and any Board Resolution may be evidenced to the Trustee by a copy thereof certified by the Secretary or an
Assistant Secretary of the Company; 
 (c) the Trustee may consult with counsel and require an Opinion of Counsel and any advice of such
counsel or Opinion of Counsel shall be full and complete authorization and protection in respect of any action taken or omitted by it hereunder in good faith and in accordance with such advice or Opinion of Counsel; 

(d) the Trustee shall not be bound to make any investigation into the facts or matters stated in any resolution, certificate, statement,
instrument, opinion, report, notice, request, direction, consent, order, bond, debenture or other paper or document, but the Trustee, in its discretion, may make such further inquiry or investigation into such facts or matters as it may see fit,
and, if the Trustee shall determine to make such further inquiry or investigation, it shall be entitled to examine the books, records and premises of the Company, personally or by agent or attorney at the expense of the Company and shall incur no
liability of any kind by reason of such inquiry or investigation; 
 (e) the Trustee may execute any of the trusts or powers hereunder or
perform any duties hereunder either directly or by or through agents, custodians, nominees or attorneys and the Trustee shall not be responsible for any misconduct or negligence on the part of any agent, custodian, nominee or attorney appointed by
it with due care hereunder; 
 (f) the permissive rights of the Trustee enumerated herein shall not be construed as duties; and 

(g) the Trustee may request that the Company deliver a certificate setting forth the names of individuals and/or titles of officers authorized
at such time to take specified actions pursuant to this Indenture. 

  
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 In no event shall the Trustee be liable for any consequential loss or damage of any kind
whatsoever (including but not limited to lost profits), even if the Trustee has been advised of the likelihood of such loss or damage and regardless of the form of action other than any such loss or damage caused by the Trustee’s willful
misconduct or gross negligence. The Trustee shall not be charged with knowledge of any Default or Event of Default with respect to the Notes, unless either (1) a Responsible Officer shall have actual knowledge of such Default or Event of
Default or (2) written notice of such Default or Event of Default shall have been given to the Trustee by the Company or by any Holder of the Notes. 

Section 7.03. No Responsibility for Recitals, Etc. The recitals contained herein and in the Notes (except in the Trustee’s
certificate of authentication) shall be taken as the statements of the Company, and the Trustee assumes no responsibility for the correctness of the same. The Trustee makes no representations as to the validity or sufficiency of this Indenture or of
the Notes. The Trustee shall not be accountable for the use or application by the Company of any Notes or the proceeds of any Notes authenticated and delivered by the Trustee in conformity with the provisions of this Indenture. The Trustee shall
have no responsibility or liability with respect to any information, statement or recital in the Offering Memorandum or other disclosure material prepared or distributed with respect to the issuance of the Notes. 

Section 7.04. Trustee, Paying Agents, Conversion Agents, Bid Solicitation Agent or Note Registrar May Own Notes. The Trustee, any
Paying Agent, any Conversion Agent, Bid Solicitation Agent or Note Registrar, in its individual or any other capacity, may become the owner or pledgee of Notes with the same rights it would have if it were not the Trustee, Paying Agent, Conversion
Agent, Bid Solicitation Agent or Note Registrar. 
 Section 7.05. Monies and Shares of Common Stock to Be Held in Trust. All
monies and shares of Common Stock received by the Trustee shall, until used or applied as herein provided, be held in trust for the purposes for which they were received. Money and shares of Common Stock held by the Trustee in trust hereunder need
not be segregated from other funds except to the extent required by law. The Trustee shall be under no liability for interest on any money or shares of Common Stock received by it hereunder except as may be agreed from time to time by the Company
and the Trustee. 
 Section 7.06. Compensation and Expenses of Trustee. The Company covenants and agrees to pay to the Trustee,
in any of its capacities under this Indenture, from time to time, and the Trustee shall be entitled to, reasonable compensation for all services rendered by it hereunder in any capacity (which shall not be limited by any provision of law in regard
to the compensation of a trustee of an express trust) as mutually agreed to in writing between the Trustee and the Company, and the Company will pay or reimburse the Trustee upon its request for all reasonable expenses, disbursements and advances
reasonably incurred or made by the Trustee in accordance with any of the provisions of this Indenture in any capacity thereunder (including the reasonable compensation and the expenses and disbursements of its agents and counsel and of all Persons
not regularly in its employ) except any such expense, disbursement or advance as shall have been 

  
 47 

 
caused by its gross negligence, willful misconduct or bad faith. The Company also covenants to indemnify the Trustee in any capacity under this Indenture and any other document or transaction
entered into in connection herewith and its officers, directors, employees, agents and any authenticating agent for, and to hold them harmless against, any loss, claim, damage, liability or expense incurred without gross negligence, willful
misconduct or bad faith on the part of the Trustee, its officers, directors, agents or employees, or such agent or authenticating agent, as the case may be, and arising out of or in connection with the acceptance or administration of this Indenture
or in any other capacity hereunder, including the costs and expenses of defending themselves against any claim of liability in the premises. The obligations of the Company under this Section 7.06 to compensate or indemnify the Trustee and to
pay or reimburse the Trustee for expenses, disbursements and advances shall be secured by a senior claim to which the Notes are hereby made subordinate on all money or property held or collected by the Trustee, except, subject to the effect of
Section 6.05, funds held in trust herewith for the benefit of the Holders of particular Notes. The Trustee’s right to receive payment of any amounts due under this Section 7.06 shall not be subordinate to any other liability or
indebtedness of the Company. The obligation of the Company under this Section 7.06 shall survive the satisfaction and discharge of this Indenture and the earlier resignation or removal or the Trustee. The Company need not pay for any settlement
made without its consent, which consent shall not be unreasonably withheld. The indemnification provided in this Section 7.06 shall extend to the officers, directors, agents and employees of the Trustee. 

Without prejudice to any other rights available to the Trustee under applicable law, when the Trustee and its agents and any authenticating
agent incur expenses or render services after an Event of Default specified in Section 6.01(h) or Section 6.01(i) occurs, the expenses and the compensation for the services are intended to constitute expenses of administration under any bankruptcy,
insolvency or similar laws. 
 Section 7.07. Officer’s Certificate and Opinion of Counsel as Evidence. Except
as otherwise provided in Section 7.01, whenever in the administration of the provisions of this Indenture the Trustee shall deem it necessary or desirable that a matter be proved or established prior to taking or omitting any action hereunder,
such matter (unless other evidence in respect thereof be herein specifically prescribed) may, in the absence of gross negligence, willful misconduct, recklessness and bad faith on the part of the Trustee, be deemed to be conclusively proved and
established by an Officer’s Certificate and Opinion of Counsel delivered to the Trustee, and such Officer’s Certificate, in the absence of gross negligence, willful misconduct, recklessness and bad faith on the part of the Trustee, shall
be full warrant to the Trustee for any action taken or omitted by it under the provisions of this Indenture upon the faith thereof. 

Section 7.08. Eligibility of Trustee. There shall at all times be a Trustee hereunder which shall be a Person that is eligible
pursuant to the Trust Indenture Act (as if the Trust Indenture Act were applicable hereto) to act as such and has a combined capital and surplus of at least $50,000,000. If such Person publishes reports of condition at least annually, pursuant to
law or to the requirements of any supervising or examining authority, then for the purposes of this Section, the combined capital and surplus of such Person shall be deemed to be its combined capital and surplus as set forth in its most recent
report of condition so published. If at any time the Trustee shall cease to be eligible in accordance with the provisions of this Section, it shall resign immediately in the manner and with the effect hereinafter specified in this Article. 

  
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 Section 7.09. Resignation or Removal of Trustee. (a) The Trustee may at any time
resign by giving written notice of such resignation to the Company and by giving notice thereof to the Holders. Upon receiving such notice of resignation, the Company shall promptly appoint a successor trustee by written instrument, in duplicate,
executed by order of the Board of Directors, one copy of which instrument shall be delivered to the resigning Trustee and one copy to the successor trustee. If no successor trustee shall have been so appointed and have accepted appointment within 60
days after the giving of such notice of resignation to the Holders, the resigning Trustee may, upon ten Business Days’ notice to the Company and the Holders, petition any court of competent jurisdiction for the appointment of a successor
trustee, or any Holder who has been a bona fide holder of a Note or Notes for at least six months (or since the date of this Indenture) may, subject to the provisions of Section 6.11, on behalf of himself or herself and all others similarly
situated, petition any such court for the appointment of a successor trustee. Such court may thereupon, after such notice, if any, as it may deem proper and prescribe, appoint a successor trustee. 

(b) In case at any time any of the following shall occur: 

(i) the Trustee shall cease to be eligible in accordance with the provisions of Section 7.08 and shall fail to resign
after written request therefor by the Company or by any such Holder, or 
 (ii) the Trustee shall become incapable of acting,
or shall be adjudged a bankrupt or insolvent, or a receiver of the Trustee or of its property shall be appointed, or any public officer shall take charge or control of the Trustee or of its property or affairs for the purpose of rehabilitation,
conservation or liquidation, 
 then, in either case, the Company may by a Board Resolution remove the Trustee and appoint a successor trustee by written
instrument, in duplicate, executed by order of the Board of Directors, one copy of which instrument shall be delivered to the Trustee so removed and one copy to the successor trustee, or, subject to the provisions of Section 6.11, any Holder
who has been a bona fide holder of a Note or Notes for at least six months (or since the date of this Indenture) may, on behalf of himself or herself and all others similarly situated, petition any court of competent jurisdiction at the expense of
the Company for the removal of the Trustee and the appointment of a successor trustee. Such court may thereupon, after such notice, if any, as it may deem proper and prescribe, remove the Trustee and appoint a successor trustee. 

(c) The Holders of a majority in aggregate principal amount of the Notes at the time outstanding, as determined in accordance with
Section 8.04, may at any time remove the Trustee and nominate a successor trustee that shall be deemed appointed as successor trustee unless within ten days after notice to the Company of such nomination the Company objects thereto, in which
case the Trustee so removed or any Holder, upon the terms and conditions and otherwise as in Section 7.09(a) provided, may petition any court of competent jurisdiction for an appointment of a successor trustee. 

(d) Any resignation or removal of the Trustee and appointment of a successor trustee pursuant to any of the provisions of this
Section 7.09 shall become effective upon acceptance of appointment by the successor trustee as provided in Section 7.10. 

  
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 Section 7.10. Acceptance by Successor Trustee. Any successor trustee appointed as
provided in Section 7.09 shall execute, acknowledge and deliver to the Company and to its predecessor trustee an instrument accepting such appointment hereunder, and thereupon the resignation or removal of the predecessor trustee shall become
effective and such successor trustee, without any further act, deed or conveyance, shall become vested with all the rights, powers, duties and obligations of its predecessor hereunder, with like effect as if originally named as Trustee herein; but,
nevertheless, on the written request of the Company or of the successor trustee, the trustee ceasing to act shall, upon payment of any amounts then due it pursuant to the provisions of Section 7.06, execute and deliver an instrument
transferring to such successor trustee all the rights and powers of the trustee so ceasing to act. Upon request of any such successor trustee, the Company shall execute any and all instruments in writing for more fully and certainly vesting in and
confirming to such successor trustee all such rights and powers. Any trustee ceasing to act shall, nevertheless, retain a senior claim to which the Notes are hereby made subordinate on all money or property held or collected by such trustee as such,
except for funds held in trust for the benefit of Holders of particular Notes, to secure any amounts then due it pursuant to the provisions of Section 7.06. 

No successor trustee shall accept appointment as provided in this Section 7.10 unless at the time of such acceptance such successor
trustee shall be eligible under the provisions of Section 7.08. 
 Upon acceptance of appointment by a successor trustee as provided in
this Section 7.10, each of the Company and the successor trustee, at the written direction and at the expense of the Company shall give or cause to be mailed notice of the succession of such trustee hereunder to the Holders at their addresses
as they shall appear on the Note Register. If the Company fails to deliver such notice within ten days after acceptance of appointment by the successor trustee, the successor trustee shall cause such notice to be delivered at the expense of the
Company. 
 Section 7.11. Succession by Merger, Etc. Any corporation or other entity into which the Trustee may be merged or
converted or with which it may be consolidated, or any corporation or other entity resulting from any merger, conversion or consolidation to which the Trustee shall be a party, or any corporation or other entity succeeding to all or substantially
all of the corporate trust business of the Trustee (including the administration of this Indenture), shall be the successor to the Trustee hereunder without the execution or filing of any paper or any further act on the part of any of the parties
hereto; provided that in the case of any corporation or other entity succeeding to all or substantially all of the corporate trust business of the Trustee such corporation or other entity shall be eligible under the provisions of
Section 7.08. 
 In case at the time such successor to the Trustee shall succeed to the trusts created by this Indenture, any of the
Notes shall have been authenticated but not delivered, any such successor to the Trustee may adopt the certificate of authentication of any predecessor trustee or authenticating agent appointed by such predecessor trustee, and deliver such Notes so
authenticated; and in case at that time any of the Notes shall not have been authenticated, any 

  
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successor to the Trustee or an authenticating agent appointed by such successor trustee may authenticate such Notes either in the name of any predecessor trustee hereunder or in the name of the
successor trustee; and in all such cases such certificates shall have the full force which it is anywhere in the Notes or in this Indenture provided that the certificate of the Trustee shall have; provided, however, that the right to
adopt the certificate of authentication of any predecessor trustee or to authenticate Notes in the name of any predecessor trustee shall apply only to its successor or successors by merger, conversion or consolidation. 

Section 7.12. Trustee’s Application for Instructions from the Company. Any application by the Trustee for
written instructions from the Company (other than with regard to any action proposed to be taken or omitted to be taken by the Trustee that affects the rights of the Holders of the Notes under this Indenture) may, at the option of the Trustee, set
forth in writing any action proposed to be taken or omitted by the Trustee under this Indenture and the date on and/or after which such action shall be taken or such omission shall be effective. The Trustee shall not be liable to the Company for any
action taken by, or omission of, the Trustee in accordance with a proposal included in such application on or after the date specified in such application (which date shall not be less than three Business Days after the date any officer that the
Company has indicated to the Trustee should receive such application actually receives such application, unless any such officer shall have consented in writing to any earlier date), unless, prior to taking any such action (or the effective date in
the case of any omission), the Trustee shall have received written instructions in accordance with this Indenture in response to such application specifying the action to be taken or omitted.. 

ARTICLE 8 

CONCERNING THE HOLDERS 

Section 8.01. Action by Holders. Whenever in this Indenture it is provided that the Holders of a specified percentage of the
aggregate principal amount of the Notes may take any action (including the making of any demand or request, the giving of any notice, consent or waiver or the taking of any other action), the fact that at the time of taking any such action, the
Holders of such specified percentage have joined therein may be evidenced (a) by any instrument or any number of instruments of similar tenor executed by Holders in person or by agent or proxy appointed in writing, or (b) by the record of
the Holders voting in favor thereof at any meeting of Holders duly called and held in accordance with the provisions of Article 9, or (c) by a combination of such instrument or instruments and any such record of such a meeting of Holders.
Whenever the Company or the Trustee solicits the taking of any action by the Holders of the Notes, the Company or the Trustee may, but shall not be required to, fix in advance of such solicitation, a date as the record date for determining Holders
entitled to take such action. The record date if one is selected shall be not more than fifteen days prior to the date of commencement of solicitation of such action. 

Section 8.02. Proof of Execution by Holders. Subject to the provisions of Section 7.01, Section 7.02 and
Section 9.05, proof of the execution of any instrument by a Holder or its agent or proxy shall be sufficient if made in accordance with such reasonable rules and regulations as may be prescribed by the Trustee or in such manner as shall be
satisfactory to the Trustee. The holding of Notes shall be proved by the Note Register or by a certificate of the Note Registrar. The record of any Holders’ meeting shall be proved in the manner provided in Section 9.06. 

  
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 Section 8.03. Who Are Deemed Absolute Owners. The Company, the Trustee, any
authenticating agent, any Paying Agent, any Conversion Agent and any Note Registrar may deem the Person in whose name a Note shall be registered upon the Note Register to be, and may treat it as, the absolute owner of such Note (whether or not such
Note shall be overdue and notwithstanding any notation of ownership or other writing thereon made by any Person other than the Company or any Note Registrar) for the purpose of receiving payment of or on account of the principal of and (subject to
Section 2.03) accrued and unpaid interest on such Note, for conversion of such Note and for all other purposes; and neither the Company nor the Trustee nor any Paying Agent nor any Conversion Agent nor any Note Registrar shall be affected by
any notice to the contrary. All such payments or deliveries so made to any Holder for the time being, or upon its order, shall be valid, and, to the extent of the sums or shares of Common Stock so paid or delivered, effectual to satisfy and
discharge the liability for monies payable or shares deliverable upon any such Note. Notwithstanding anything to the contrary in this Indenture or the Notes following an Event of Default, any holder of a beneficial interest in a Global Note may
directly enforce against the Company, without the consent, solicitation, proxy, authorization or any other action of the Depositary or any other Person, such holder’s right to exchange such beneficial interest for a Note in certificated form in
accordance with the provisions of this Indenture. 
 Section 8.04. Company-Owned Notes Disregarded. In determining whether the
Holders of the requisite aggregate principal amount of Notes have concurred in any direction, consent, waiver or other action under this Indenture, Notes that are owned by the Company or by any Subsidiary thereof shall be disregarded and deemed not
to be outstanding for the purpose of any such determination; provided that for the purposes of determining whether the Trustee shall be protected in relying on any such direction, consent, waiver or other action only Notes that a Responsible
Officer knows are so owned shall be so disregarded. Notes so owned that have been pledged in good faith may be regarded as outstanding for the purposes of this Section 8.04 if the pledgee shall establish to the satisfaction of the Trustee the
pledgee’s right to so act with respect to such Notes and that the pledgee is not the Company, a Subsidiary thereof or a Person directly or indirectly controlling or controlled by or under direct or indirect common control with the Company or a
Subsidiary thereof. In the case of a dispute as to such right, any decision by the Trustee taken upon the advice of counsel shall be full protection to the Trustee. Upon request of the Trustee, the Company shall furnish to the Trustee promptly an
Officer’s Certificate listing and identifying all Notes, if any, known by the Company to be owned or held by or for the account of any of the above described Persons; and, subject to Section 7.01, the Trustee shall be entitled to accept
such Officer’s Certificate as conclusive evidence of the facts therein set forth and of the fact that all Notes not listed therein are outstanding for the purpose of any such determination. 

Section 8.05. Revocation of Consents; Future Holders Bound. At any time prior to (but not after) the evidencing to the Trustee, as
provided in Section 8.01, of the taking of any action by the Holders of the percentage of the aggregate principal amount of the Notes specified in this Indenture in connection with such action, any Holder of a Note that is shown by the evidence
to 

  
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be included in the Notes the Holders of which have consented to such action may, by filing written notice with the Trustee at its Corporate Trust Office and upon proof of holding as provided in
Section 8.02, revoke such action so far as concerns such Note. Except as aforesaid, any such action taken by the Holder of any Note shall be conclusive and binding upon such Holder and upon all future Holders and owners of such Note and of any
Notes issued in exchange or substitution therefor or upon registration of transfer thereof, irrespective of whether any notation in regard thereto is made upon such Note or any Note issued in exchange or substitution therefor or upon registration of
transfer thereof. 
 ARTICLE 9 

HOLDERS’ MEETINGS 

Section 9.01. Purpose of Meetings. A meeting of Holders may be called at any time and from time to time pursuant to the provisions
of this Article 9 for any of the following purposes: 
 (a) to give any notice to the Company or to the Trustee or to give any directions to
the Trustee permitted under this Indenture, or to consent to the waiving of any Default or Event of Default hereunder (in each case, as permitted under this Indenture) and its consequences, or to take any other action authorized to be taken by
Holders pursuant to any of the provisions of Article 6; 
 (b) to remove the Trustee and nominate a successor trustee pursuant to the
provisions of Article 7; 
 (c) to consent to the execution of an indenture or indentures supplemental hereto pursuant to the provisions of
Section 10.02; or 
 (d) to take any other action authorized to be taken by or on behalf of the Holders of any specified aggregate
principal amount of the Notes under any other provision of this Indenture or under applicable law. 
 Section 9.02. Call of Meetings
by Trustee. The Trustee may at any time call a meeting of Holders to take any action specified in Section 9.01, to be held at such time and at such place as the Trustee shall determine. Notice of every meeting of the Holders, setting forth
the time and the place of such meeting and in general terms the action proposed to be taken at such meeting and the establishment of any record date pursuant to Section 8.01, shall be given to Holders of such Notes at their addresses as they
shall appear on the Note Register. Such notice shall also be given to the Company. Such notices shall be given not less than 20 nor more than 90 days prior to the date fixed for the meeting. 

Any meeting of Holders shall be valid without notice if the Holders of all Notes then outstanding are present in person or by proxy or if
notice is waived before or after the meeting by the Holders of all Notes then outstanding, and if the Company and the Trustee are either present by duly authorized representatives or have, before or after the meeting, waived notice. 

  
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 Section 9.03. Call of Meetings by Company or Holders. In case at any time the
Company, pursuant to a Board Resolution, or the Holders of at least 10% of the aggregate principal amount of the Notes then outstanding, shall have requested the Trustee to call a meeting of Holders, by written request setting forth in reasonable
detail the action proposed to be taken at the meeting, and the Trustee shall not have given the notice of such meeting within 20 days after receipt of such request, then the Company or such Holders may determine the time and the place for such
meeting and may call such meeting to take any action authorized in Section 9.01, by giving notice thereof as provided in Section 9.02. 

Section 9.04. Qualifications for Voting. To be entitled to vote at any meeting of Holders a Person shall (a) be a Holder of
one or more Notes on the record date pertaining to such meeting or (b) be a Person appointed by an instrument in writing as proxy by a Holder of one or more Notes on the record date pertaining to such meeting. The only Persons who shall be
entitled to be present or to speak at any meeting of Holders shall be the Persons entitled to vote at such meeting and their counsel and any representatives of the Trustee and its counsel and any representatives of the Company and its counsel. 

Section 9.05. Regulations. Notwithstanding any other provisions of this Indenture, the Trustee may make such reasonable
regulations as it may deem advisable for any meeting of Holders, in regard to proof of the holding of Notes and of the appointment of proxies, and in regard to the appointment and duties of inspectors of votes, the submission and examination of
proxies, certificates and other evidence of the right to vote, and such other matters concerning the conduct of the meeting as it shall think fit. 

The Trustee shall, by an instrument in writing, appoint a temporary chairman of the meeting, unless the meeting shall have been called by the
Company or by Holders as provided in Section 9.03, in which case the Company or the Holders calling the meeting, as the case may be, shall in like manner appoint a temporary chairman. A permanent chairman and a permanent secretary of the
meeting shall be elected by vote of the Holders of a majority in aggregate principal amount of the Notes represented at the meeting and entitled to vote at the meeting. 

Subject to the provisions of Section 8.04, at any meeting of Holders each Holder or proxyholder shall be entitled to one vote for each
$1,000 principal amount of Notes held or represented by him or her; provided, however, that no vote shall be cast or counted at any meeting in respect of any Note challenged as not outstanding and ruled by the chairman of the meeting
to be not outstanding. The chairman of the meeting shall have no right to vote other than by virtue of Notes held by it or instruments in writing as aforesaid duly designating it as the proxy to vote on behalf of other Holders. Any meeting of
Holders duly called pursuant to the provisions of Section 9.02 or Section 9.03 may be adjourned from time to time by the Holders of a majority of the aggregate principal amount of Notes represented at the meeting, whether or not
constituting a quorum, and the meeting may be held as so adjourned without further notice. 
 Section 9.06. Voting. The vote
upon any resolution submitted to any meeting of Holders shall be by written ballot on which shall be subscribed the signatures of the Holders or of their representatives by proxy and the outstanding aggregate principal amount of the Notes held or
represented by them. The permanent chairman of the meeting shall appoint two inspectors of votes who shall count all votes cast at the meeting for or against any resolution and who shall 

  
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make and file with the secretary of the meeting their verified written reports in duplicate of all votes cast at the meeting. A record in duplicate of the proceedings of each meeting of Holders
shall be prepared by the secretary of the meeting and there shall be attached to said record the original reports of the inspectors of votes on any vote by ballot taken thereat and affidavits by one or more Persons having knowledge of the facts
setting forth a copy of the notice of the meeting and showing that said notice was mailed as provided in Section 9.02. The record shall show the aggregate principal amount of the Notes voting in favor of or against any resolution. The record
shall be signed and verified by the affidavits of the permanent chairman and secretary of the meeting and one of the duplicates shall be delivered to the Company and the other to the Trustee to be preserved by the Trustee, the latter to have
attached thereto the ballots voted at the meeting. 
 Any record so signed and verified shall be conclusive evidence of the matters therein
stated. 
 Section 9.07. No Delay of Rights by Meeting. Nothing contained in this Article 9 shall be deemed or construed to
authorize or permit, by reason of any call of a meeting of Holders or any rights expressly or impliedly conferred hereunder to make such call, any hindrance or delay in the exercise of any right or rights conferred upon or reserved to the Trustee or
to the Holders under any of the provisions of this Indenture or of the Notes. 
 ARTICLE 10 

SUPPLEMENTAL INDENTURES 

Section 10.01. Supplemental Indentures Without Consent of Holders. The Company and the Trustee, at the Company’s expense, may
from time to time and at any time enter into an indenture or indentures supplemental hereto for one or more of the following purposes: 

(a) to cure any ambiguity, omission, defect or inconsistency; 

(b) to provide for the assumption by a Successor Person of the obligations of the Company under the Notes and this Indenture pursuant to
Article 11; 
 (c) to add guarantees with respect to the Notes; 

(d) to provide for the issuance of additional Notes; 

(e) to secure the Notes; 
 (f)
to add to the covenants or Events of Default of the Company for the benefit of the Holders or surrender any right or power conferred upon the Company under this Indenture; 

(g) to make any change that does not adversely affect the rights of any Holder in any material respect; 

  
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 (h) in connection with any Common Stock Change Event, subject to the provisions of
Section 14.02, to provide that the Notes are convertible into Reference Property and make such related changes to the terms of the Notes to the extent expressly required by Section 14.07; 

(i) comply with any requirement of the Commission in connection with the qualification of this Indenture under the Trust Indenture Act; 

(j) to appoint a successor trustee with respect to the Notes 

(k) to conform the provisions of this Indenture or the Notes to the “Description of notes” section of the Offering Memorandum; or

 (l) to irrevocably elect or eliminate one of the Settlement Methods and/or irrevocably elect a minimum Specified Dollar Amount. 

Upon the written request of the Company, the Trustee is hereby authorized to join with the Company in the execution of any such supplemental
indenture, to make any further appropriate agreements and stipulations that may be therein contained, but the Trustee shall not be obligated to, but may in its discretion, enter into any supplemental indenture that affects the Trustee’s own
rights, duties or immunities under this Indenture or otherwise. 
 Any supplemental indenture authorized by the provisions of this
Section 10.01 may be executed by the Company and the Trustee without the consent of the Holders of any of the Notes at the time outstanding, notwithstanding any of the provisions of Section 10.02. 

Section 10.02. Supplemental Indentures with Consent of Holders. With the consent (evidenced as provided in Article 8) of the
Holders of at least a majority of the aggregate principal amount of the Notes then outstanding (determined in accordance with Article 8 and including, without limitation, consents obtained in connection with a repurchase of, or tender or exchange
offer for, Notes), the Company and the Trustee, at the Company’s expense, may from time to time and at any time enter into an indenture or indentures supplemental hereto for the purpose of adding any provisions to or changing in any manner,
waiving or eliminating any of the provisions of this Indenture or the Notes or any supplemental indenture or of modifying in any manner the rights of the Holders; provided, however, that, without the consent of each Holder of an
outstanding Note affected, no such supplemental indenture shall: 
 (a) reduce the principal amount of Notes whose Holders must consent to
an amendment; 
 (b) reduce the rate of or extend the stated time for payment of interest on any Note; 

(c) reduce the principal of or extend the Maturity Date of any Note; 

(d) make any change that adversely affects the conversion rights of any Notes; 

(e) reduce the Fundamental Change Repurchase Price of any Note or amend or modify in any manner adverse to the Holders the Company’s
obligation to make such payments, whether through an amendment or waiver of provisions in the covenants, definitions or otherwise; 

  
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 (f) make any Note payable in a currency, or at a place of payment, other than that stated in the
Note; 
 (g) change the ranking of the Notes; or 

(h) make any change in this Article 10 that requires each Holder’s consent or in the waiver provisions in Section 6.02 or
Section 6.09. 
 Upon the written request of the Company, and upon the filing with the Trustee of evidence of the consent of Holders as
aforesaid and subject to Section 10.05, the Trustee shall join with the Company in the execution of such supplemental indenture unless such supplemental indenture affects the Trustee’s own rights, duties or immunities under this Indenture
or otherwise, in which case the Trustee may in its discretion, but shall not be obligated to, enter into such supplemental indenture. 

Holders do not need under this Section 10.02 to approve the particular form of any proposed supplemental indenture. It shall be
sufficient if such Holders approve the substance thereof. After any such supplemental indenture becomes effective, the Company shall give to the Holders a notice (with a copy to the Trustee) briefly describing such supplemental indenture. However,
the failure to give such notice to all the Holders, or any defect in the notice, will not impair or affect the validity of the supplemental indenture. 

Section 10.03. Effect of Supplemental Indentures. Upon the execution of any supplemental indenture pursuant to the provisions of
this Article 10, this Indenture shall be and be deemed to be modified and amended in accordance therewith and the respective rights, limitation of rights, obligations, duties and immunities under this Indenture of the Trustee, the Company and the
Holders shall thereafter be determined, exercised and enforced hereunder subject in all respects to such modifications and amendments and all the terms and conditions of any such supplemental indenture shall be and be deemed to be part of the terms
and conditions of this Indenture for any and all purposes. 
 Section 10.04. Notation on Notes. Notes authenticated and
delivered after the execution of any supplemental indenture pursuant to the provisions of this Article 10 may, at the Company’s expense, bear a notation in form approved by the Trustee as to any matter provided for in such supplemental
indenture. If the Company or the Trustee shall so determine, new Notes so modified as to conform, in the opinion of the Trustee and Company, to any modification of this Indenture contained in any such supplemental indenture may, at the
Company’s expense, be prepared and executed by the Company, authenticated by the Trustee (or an authenticating agent duly appointed by the Trustee pursuant to Section 17.10) and delivered in exchange for the Notes then outstanding, upon
surrender of such Notes then outstanding. 
 Section 10.05. Evidence of Compliance of Supplemental Indenture to Be Furnished
Trustee. In addition to the documents required by Section 17.05, the Trustee shall receive an Officer’s Certificate and an Opinion of Counsel as conclusive evidence that any supplemental indenture executed pursuant hereto complies with
the requirements of this Article 10, is permitted or authorized by this Indenture and is the legal, valid and binding obligation of the Company, enforceable against the Company in accordance with such supplemental indenture’s terms. 

  
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 ARTICLE 11 

CONSOLIDATION, MERGER, SALE, CONVEYANCE AND LEASE 

Section 11.01. Company May Consolidate, Etc. on Certain Terms. Subject to the provisions of Section 11.02, the Company shall
not consolidate with, merge with or into, or sell, convey, transfer or lease all or substantially all of the properties and assets of the Company to, another Person, unless: 

(a) Either (i) the Company is the Person surviving such merger or consolidation, or (ii) the Person (if other than the Company)
formed by such consolidation or into which the Company is merged or the Person who acquires by conveyance or transfer or which leases all or substantially all of the Company’s assets (the “Successor Person”), shall be a
corporation organized and validly existing under the laws of the United States of America, any State thereof or the District of Columbia, and in the case where there is a Successor Person, such Successor Person shall expressly assume, by
supplemental indenture all of the obligations of the Company under the Notes and this Indenture; 
 (b) immediately after giving effect to
such transaction, no Default or Event of Default shall have occurred and be continuing under this Indenture; and 
 (c) in such transaction
where there is a Successor Person other than the Company, the Company and the Successor Person shall have delivered to the Trustee the Officer’s Certificate and an Opinion of Counsel provided for in Section 11.03. 

For purposes of this Section 11.01, the sale, conveyance, transfer or lease of all or substantially all of the properties and assets of
one or more Subsidiaries of the Company to another Person, which properties and assets, if held by the Company instead of such Subsidiaries, would constitute all or substantially all of the properties and assets of the Company on a consolidated
basis, shall be deemed to be the sale, conveyance, transfer or lease of all or substantially all of the properties and assets of the Company to another Person. 

Section 11.02. Successor Corporation to Be Substituted. In case of any such consolidation, merger, sale, conveyance, transfer or
lease and upon the assumption by the Successor Person, by supplemental indenture, executed and delivered to the Trustee and satisfactory in form to the Trustee, of the due and punctual payment of the principal of and accrued and unpaid interest on
all of the Notes, the due and punctual delivery or payment, as the case may be, of any consideration due upon conversion of the Notes and the due and punctual performance of all of the covenants and conditions of this Indenture to be performed by
the Company, such Successor Person shall succeed to and, except in the case of a lease of all or substantially all of the consolidated properties and assets of the Company and its Subsidiaries, taken as a whole, shall be substituted for the Company,
with the same effect as if it had been named herein as the party of the first part. Such Successor Person thereupon may cause to be signed, and may issue either in its own name or in the name of the Company any or all of the

  
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Notes issuable hereunder which theretofore shall not have been signed by the Company and delivered to the Trustee; and, upon the order of such Successor Person instead of the Company and subject
to all the terms, conditions and limitations in this Indenture prescribed, the Trustee shall authenticate and shall deliver, or cause to be authenticated and delivered, any Notes that previously shall have been signed and delivered by the Officers
of the Company to the Trustee for authentication, and any Notes that such Successor Person thereafter shall cause to be signed and delivered to the Trustee for that purpose. All the Notes so issued shall in all respects have the same legal rank and
benefit under this Indenture as the Notes theretofore or thereafter issued in accordance with the terms of this Indenture as though all of such Notes had been issued at the date of the execution hereof. In the event of any such consolidation,
merger, sale, conveyance or transfer (but not in the case of a lease), upon compliance with this Article 11 the Person named as the “Company” in the first paragraph of this Indenture (or any successor that shall thereafter have become such
in the manner prescribed in this Article 11) may be dissolved, wound up and liquidated at any time thereafter and, except in the case of a lease, such Person shall be released from its liabilities as obligor and maker of the Notes and from its
obligations under this Indenture and the Notes. 
 In case of any such consolidation, merger, sale, conveyance, transfer or lease, such
changes in phraseology and form (but not in substance) may be made in the Notes thereafter to be issued as may be appropriate. 

Section 11.03. Opinion of Counsel to Be Given to Trustee. If the Successor Person is not the Company, no such consolidation,
merger, sale, conveyance, transfer or lease shall be effective unless the Trustee shall receive an Officer’s Certificate and an Opinion of Counsel certifying that any such consolidation, merger, sale, conveyance, transfer or lease and any such
assumption and, if a supplemental indenture is required in connection with such transaction, such supplemental indenture, complies with the provisions of this Indenture and that the supplemental indenture is the valid, binding obligations of the
Successor Person, enforceable against such Successor Person in accordance with its terms, such Opinion of Counsel to be subject to customary exceptions. 

ARTICLE 12 

IMMUNITY OF INCORPORATORS, STOCKHOLDERS, OFFICERS AND
DIRECTORS 
 Section 12.01. Indenture and Notes Solely Corporate Obligations. No recourse for the payment of the
principal of or accrued and unpaid interest on any Note, nor for any claim based thereon or otherwise in respect thereof, and no recourse under or upon any obligation, covenant or agreement of the Company in this Indenture or in any supplemental
indenture or in any Note, nor because of the creation of any indebtedness represented thereby, shall be had against any incorporator, stockholder, employee, agent, Officer or director or Subsidiary, as such, past, present or future, of the Company
or of any successor corporation, either directly or through the Company or any successor corporation, whether by virtue of any constitution, statute or rule of law, or by the enforcement of any assessment or penalty or otherwise; it being expressly
understood that all such liability is hereby expressly waived and released as a condition of, and as a consideration for, the execution of this Indenture and the issue of the Notes. 

  
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 ARTICLE 13 

RESERVED 
 ARTICLE
14 
 CONVERSION OF NOTES 

Section 14.01. Conversion Privilege. (a) Subject to and upon compliance with the provisions of this Article 14, each Holder
of a Note shall have the right, at such Holder’s option, to convert all or any portion (if the portion to be converted is $1,000 principal amount or an integral multiple thereof) of such Note (i) subject to satisfaction of one or more of
the conditions described in Section 14.01(b), at any time prior to the close of business on the Business Day immediately preceding September 15, 2021, and (ii) regardless of the conditions described in Section 14.01(b), on or after
September 15, 2021 and prior to the close of business on the Business Day immediately preceding the Maturity Date, in each case, at an initial conversion rate of 82.3893 shares of Common Stock (subject to adjustment as provided in this Article
14, the “Conversion Rate”) per $1,000 principal amount of Notes (subject to, and in accordance with, the settlement provisions of Section 14.02, the “Conversion Obligation”). 

(b) (i) Prior to the close of business on the Business Day immediately preceding September 15, 2021, a Holder may surrender all or any
portion of its Notes for conversion at any time during the five Business Day period immediately after any five consecutive Trading Day period (the “Measurement Period”) in which the Trading Price per $1,000 principal amount of
Notes, as determined following a request by a Holder of Notes in accordance with this subsection (b)(i), for each Trading Day of the Measurement Period was less than 98% of the product of the Last Reported Sale Price of the Common Stock and the
Conversion Rate on each such Trading Day. The Trading Prices shall be determined using bids solicited by the Bid Solicitation Agent, all pursuant to this subsection (b)(i) and the definition of Trading Price set forth in this Indenture. The Company
shall provide written notice to the Bid Solicitation Agent of the three independent nationally recognized securities dealers selected by the Company pursuant to the definition of Trading Price, along with appropriate contact information for each.
The Bid Solicitation Agent (if other than the Company) shall have no obligation to determine the Trading Price per $1,000 principal amount of Notes in the manner set forth in this subsection (b)(i) and the definition of Trading Price set forth in
this Indenture unless the Company has requested such determination (or, if the Company is acting as Bid Solicitation Agent, the Company shall have no obligation to determine the Trading Price per $1,000 principal amount of Notes); and the Company
shall have no obligation to make such request (or make such determination) unless a Holder of at least $3,000,000 aggregate principal amount of Notes provides the Company with reasonable evidence that the Trading Price per $1,000 principal amount of
Notes would be less than 98% of the product of the Last Reported Sale Price of the Common Stock and the Conversion Rate and such Holder requests that the Company request that the Bid Solicitation Agent to determine or, if the Company is acting as
Bid Solicitation Agent, requests that the Company determine, the Trading Price per $1,000 principal amount of Notes. At such time, the Company shall instruct the Bid Solicitation Agent (if other than the Company) to determine, or if the Company is
acting as Bid Solicitation Agent, the Company shall determine, the Trading Price per $1,000 principal amount of Notes, beginning on the next Trading Day and on each successive Trading Day until 

  
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the Trading Price per $1,000 principal amount of Notes is greater than or equal to 98% of the product of the Last Reported Sale Price of the Common Stock and the Conversion Rate. The Trading
Price shall be determined based on the bids received from the Bid Solicitation Agent pursuant to this clause (b)(i) and the definition of Trading Price set forth in this Indenture. If (x) the Company is not acting as Bid Solicitation Agent, and
the Company does not, when required to, instruct the Bid Solicitation Agent to obtain bids, or if the Company gives such instruction to the Bid Solicitation Agent, and the Bid Solicitation Agent fails to make such determination, or (y) the
Company is acting as Bid Solicitation Agent and the Company fails to carry out such determination, then, in either case, the Trading Price per $1,000 principal amount of Notes shall be deemed to be less than 98% of the product of the Last Reported
Sale Price of the Common Stock and the Conversion Rate on each Trading Day of such failure. If the Trading Price condition set forth above has been met, the Company shall so notify the Holders, the Trustee and the Conversion Agent (if other than the
Trustee) in writing. If, at any time after the Trading Price condition set forth above has been met, the Trading Price per $1,000 principal amount of Notes is greater than or equal to 98% of the product of the Last Reported Sale Price of the Common
Stock and the Conversion Rate for such date, the Company shall so notify the Holders of the Notes, the Trustee and the Conversion Agent (if other than the Trustee) in writing that the Trading Price condition is no longer applicable. None of the
Trustee, the Bid Solicitation Agent (if the Trustee) or the Conversion Agent (if the Trustee) shall have any duty to determine or to verify the Company’s determination of whether the Trading Price condition set forth above has been met. 

(ii) If, prior to the close of business on the Business Day immediately preceding September 15, 2021, the Company elects
to: 
 (A) issue to all or substantially all holders of the Common Stock any rights, options or warrants (other than pursuant
to a stockholders rights plan prior to the separation of the rights thereunder) entitling them, for a period of not more than 45 calendar days after the announcement date of such issuance, to subscribe for or purchase Common Stock at a price per
share that is less than the average of the Last Reported Sale Price of the Common Stock for the 10 consecutive Trading Day period ending on, and including, the Trading Day immediately preceding the date of announcement of such issuance; or 

(B) distribute to all or substantially all holders of the Common Stock the Company’s assets, securities or rights to
purchase securities of the Company, which distribution has a per share value, as reasonably determined by the Board of Directors, exceeding 10% of the Last Reported Sale Price of the Common Stock on the Trading Day preceding the date of announcement
for such distribution, 
 then, in either case, the Company shall notify in writing all Holders of the Notes, the Trustee and the Conversion Agent (if other
than the Trustee) at least 45 Scheduled Trading Days prior to the Ex-Dividend Date for such issuance or distribution. Once the Company has given such notice, a Holder may surrender all or any portion of its
Notes for conversion at any time until the earlier of (1) the close of business on the Business Day immediately preceding the Ex-Dividend Date for such issuance or distribution and (2) the
Company’s announcement that such issuance or 

  
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distribution will not take place, in each case, even if the Notes are not otherwise convertible at such time. Holders of the Notes may not exercise this right if they participate (other than in
the case of a share split or share combination), at the same time and upon the same terms as holders of Common Stock and solely as a result of holding the Notes, in any of the transactions described in this subsection (b)(ii) without having to
convert their Notes as if they held a number of shares of Common Stock equal to the applicable Conversion Rate multiplied by the principal amount (expressed in thousands) of Notes held by such Holder. None of the Trustee or the Conversion Agent (if
the Trustee) shall have any duty to determine or to verify the Company’s determination of whether an issuance or distribution in this clause (ii) has occurred. 

(iii) If (A) a transaction or event that constitutes a Fundamental Change or a Make-Whole Fundamental Change occurs prior
to the close of business on the Business Day immediately preceding September 15, 2021, regardless of whether a Holder has the right to require the Company to repurchase the Notes pursuant to Section 15.02, or (B) the Company is a
party to a consolidation, merger, binding share exchange, or transfer or lease of all or substantially all of the Company’s assets (other than a merger effected solely to change the Company’s jurisdiction of incorporation that does not
otherwise constitute a Fundamental Change or Make-Whole Fundamental Change), prior to the close of business on the Business Day immediately preceding September 15, 2021 and pursuant to which the Common Stock would be converted into cash,
securities or other assets, then, in the case of either (A) or (B), all or any portion of a Holder’s Notes may be surrendered for conversion at any time from or after the effective date of such transaction until 35 Trading Days after such
effective date or, if such transaction also constitutes a Fundamental Change, until the related Fundamental Change Repurchase Date. The Company shall notify Holders, the Trustee and the Conversion Agent (if other than the Trustee) within one
Business Day of the date the Company publicly announces such transaction, but in no event later than the actual effective date of such transaction. None of the Trustee or the Conversion Agent (if the Trustee) shall have any duty to determine or to
verify the Company’s determination of whether a Fundamental Change or a Make-Whole Fundamental Change has occurred. 

(iv) Prior to the close of business on the Business Day immediately preceding September 15, 2021, a Holder may surrender
all or any portion of its Notes for conversion at any time during any calendar quarter commencing after the calendar quarter ending on March 31, 2017 (and only during such calendar quarter), if the Last Reported Sale Price of the Common Stock
for at least 20 Trading Days (whether or not consecutive) during the period of 30 consecutive Trading Days ending on the last Trading Day of the immediately preceding calendar quarter is greater than or equal to 120% of the Conversion Price on each
applicable Trading Day. The Company shall determine at the beginning of each calendar quarter commencing after March 31, 2017 whether the Notes may be surrendered for conversion in accordance with this clause (iv) and shall notify in
writing the Holders of the Notes, the Trustee and the Conversion Agent (if other than the Trustee) if the Notes become convertible in accordance with this clause (iv). None of the Trustee or the Conversion Agent (if the Trustee) shall have any duty
to determine or to verify the Company’s determination of whether the condition set forth in this clause (iv) has been met. 

  
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 (c) (i) For any Conversion Date that occurs on or after the date that is one year after the last
date of original issuance of the Notes, if the Last Reported Sale Price of the Common Stock for at least 20 Trading Days (whether or not consecutive) during the period of 30 consecutive Trading Days ending within the five Trading Days immediately
preceding a Conversion Date is greater than or equal to 120% of the Conversion Price on each applicable Trading Day, the Company shall make an interest make-whole payment to a converting Holder (other than a conversion “in connection with”
a Make-Whole Fundamental Change in which the Conversion Rate is adjusted pursuant to Section 14.03) equal to the sum of the present values of the scheduled payments of interest that would have been made on the Notes to be converted had such
Notes remained outstanding from the Conversion Date through the earlier of (i) the date that is three years after the Conversion Date and (ii) the Maturity Date if the notes had not been so converted (an “Interest Make-Whole
Payment”). The present values of the remaining interest payments will be computed using a discount rate equal to 2.0%. Such present value shall be computed by the Company in good faith. Notwithstanding the foregoing, if in connection with
any conversion the Conversion Rate is adjusted pursuant to Section 14.03, then such Holder will not receive the Interest Make-Whole Payment with respect to such Note. None of the Trustee, Paying Agent or Conversion Agent shall be responsible
for determining or calculating the Interest Make-Whole Payment or the Daily VWAP. 
 (ii) The Company may pay any Interest
Make-Whole Payment either in cash or in shares of Common Stock, at its election. If the Company does not make such election, the payment of any Interest Make-Whole Payment shall be in shares of Common Stock. If the Company elects, or is deemed to
have elected, to pay any Interest Make-Whole Payment by delivering shares of Common Stock, the number of shares of Common Stock a converting Holder shall receive will be the number of shares that have a value equal to the amount of the Interest
Make-Whole Payment to be paid to such Holder in shares of Common Stock, divided by the product of (x) 95% and (y) the simple average of the Daily VWAP of the Common Stock for the 10 Trading Days ending on and including the Trading Day
immediately preceding the Conversion Date. The Company will pay cash in lieu of delivering any fractional share of Common Stock in accordance with subsection (j) of Section 14.02. If the Company elects to pay any Interest Make-Whole
Payment in cash the Company will pay cash in an amount equal to the Interest Make-Whole Payment. 
 (iii) If a Conversion
Date occurs after the close of business on a Regular Record Date but prior to the open of business on the Interest Payment Date corresponding to such Regular Record Date, the Company will not pay accrued interest to any converting Holder and will
instead pay the full amount of the relevant interest payment on such Interest Payment Date to the Holder of record on such Regular Record Date. In such case, the Interest Make-Whole Payment to such converting Holder will equal the present value of
all remaining interest payments, starting with the next Interest Payment Date for which interest has not been provided for until the earlier of (i) the date that is three years after the Conversion Date and (ii) the Maturity Date if the
Notes had not been so converted, computed in the manner described above using a discount rate equal to 2.0%. 

  
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 Section 14.02. Conversion Procedure; Settlement Upon Conversion. 

(a) Subject to this Section 14.02, Section 14.03(b) and Section 14.07(a), upon conversion of any Note, the Company shall satisfy its
Conversion Obligation by paying or delivering, as the case may be, to the converting Holder, in respect of each $1,000 principal amount of Notes being converted, cash (“Cash Settlement”), shares of Common Stock, together with cash,
if applicable, in lieu of delivering any fractional share of Common Stock in accordance with subsection (j) of this Section 14.02 (“Physical Settlement”) or a combination of cash and shares of Common Stock, together with a
cash payment, if applicable, in lieu of delivering any fractional share of Common Stock in accordance with subsection (j) of this Section 14.02 (“Combination Settlement”), at its election, as set forth in this
Section 14.02, and an Interest Make-Whole Payment, if applicable. 
 (i) All conversions for which the relevant
Conversion Date occurs on or after September 15, 2021 shall be settled using the same Settlement Method. 
 (ii) Except
for any conversions for which the relevant Conversion Date occurs on or after September 15, 2021, the Company shall use the same Settlement Method for all conversions with the same Conversion Date, but the Company shall not have any obligation
to use the same Settlement Method with respect to conversions with different Conversion Dates. 
 (iii) If, in respect of any
Conversion Date (or the period described in the third immediately succeeding set of parentheses, as the case may be), the Company elects to deliver a notice (the “Settlement Notice”) of the relevant Settlement Method in respect of
such Conversion Date (or such period, as the case may be), the Company shall deliver such Settlement Notice in writing to converting Holders, the Trustee and the Conversion Agent (if other than the Trustee) no later than the close of business on the
Trading Day immediately following the relevant Conversion Date (or, in the case of any conversions for which the relevant Conversion Date occurs on or after September 15, 2021, no later than September 15, 2021). If the Company does not
elect a Settlement Method prior to the deadline set forth in the immediately preceding sentence, the Company shall no longer have the right to elect Cash Settlement or Physical Settlement with respect to any conversion on such Conversion Date or
during such period, as the case may be, and the Company shall be deemed to have elected Combination Settlement in respect of its Conversion Obligation, and the Specified Dollar Amount per $1,000 principal amount of Notes shall be equal to $1,000.
Such Settlement Notice shall specify the relevant Settlement Method and in the case of an election of Combination Settlement, the relevant Settlement Notice shall indicate the Specified Dollar Amount per $1,000 principal amount of Notes to be
converted. If the Company delivers a Settlement Notice electing Combination Settlement in respect of its Conversion Obligation but does not indicate a Specified Dollar Amount per $1,000 principal amount of Notes in such Settlement Notice, the
Specified Dollar Amount per $1,000 principal amount of Notes to be converted shall be deemed to be $1,000. 

  
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 (iv) The cash, shares of Common Stock or combination of cash and shares of Common
Stock in respect of any conversion of Notes (the “Settlement Amount”) shall be computed as follows: 
 (A)
if the Company elects to satisfy its Conversion Obligation in respect of such conversion by Physical Settlement, the Company shall deliver to the converting Holder in respect of each $1,000 principal amount of Notes being converted a number of
shares of Common Stock equal to the Conversion Rate in effect on the Conversion Date and the Interest Make-Whole Payment, if any; 

(B) if the Company elects to satisfy its Conversion Obligation in respect of such conversion by Cash Settlement, the Company
shall pay to the converting Holder in respect of each $1,000 principal amount of Notes being converted cash in an amount equal to the sum of the Daily Conversion Values for each of the 40 consecutive Trading Days during the related Observation
Period and the Interest Make-Whole Payment, if any; and 
 (C) if the Company elects (or is deemed to have elected) to
satisfy its Conversion Obligation in respect of such conversion by Combination Settlement, the Company shall pay or deliver, as the case may be, in respect of each $1,000 principal amount of Notes being converted, a Settlement Amount equal to the
sum of the Daily Settlement Amounts for each of the 40 consecutive Trading Days during the related Observation Period and the Interest Make-Whole Payment, if any. 

(v) The Daily Settlement Amounts (if applicable) and the Daily Conversion Values (if applicable) shall be determined by the
Company promptly following the last day of the Observation Period. Promptly after such determination of the Daily Settlement Amounts or the Daily Conversion Values, as the case may be, and the amount of cash payable in lieu of delivering any
fractional share of Common Stock, the Company shall notify the Trustee and the Conversion Agent (if other than the Trustee) of the Daily Settlement Amounts or the Daily Conversion Values, as the case may be, and the amount of cash payable in lieu of
delivering fractional shares of Common Stock. The Trustee and the Conversion Agent (if other than the Trustee) shall have no responsibility for any such determination. 

(b) Subject to Section 14.02(e), before any Holder of a Note shall be entitled to convert a Note as set forth above, such Holder shall
(i) in the case of a Global Note, comply with the procedures of the Depositary in effect at that time and, if required, pay funds equal to interest payable on the next Interest Payment Date to which such Holder is not entitled as set forth in
Section 14.02(h) and (ii) in the case of a Physical Note (1) complete, manually sign and deliver an irrevocable notice to the Conversion Agent as set forth in the Form of Notice of Conversion (or a facsimile thereof) (a “Notice of
Conversion”) at the office of the Conversion Agent and state in writing therein the principal amount of Notes to be converted and the name or names (with addresses) in which such Holder wishes the certificate or certificates for any shares
of Common Stock to be delivered upon settlement of the Conversion Obligation (and settlement of any Interest Make-Whole Payment, applicable) to be registered, (2) surrender such Notes, duly 

  
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endorsed to the Company or in blank (and accompanied by appropriate endorsement and transfer documents), at the office of the Conversion Agent, (3) if required, furnish appropriate
endorsements and transfer documents and (4) if required, pay funds equal to interest payable on the next Interest Payment Date to which such Holder is not entitled as set forth in Section 14.02(h). The Trustee (and if different, the Conversion
Agent) shall notify the Company of any conversion pursuant to this Article 14 on the Conversion Date for such conversion. No Notice of Conversion with respect to any Notes may be surrendered by a Holder thereof if such Holder has also delivered a
Fundamental Change Repurchase Notice to the Company in respect of such Notes and has not validly withdrawn such Fundamental Change Repurchase Notice in accordance with Section 15.03, in the case of Physical Notes, or through the applicable
procedures of the Depositary, in the case of Global Notes. 
 If more than one Note shall be surrendered for conversion at one time by the
same Holder, the Conversion Obligation and Interest Make-Whole Payment, if applicable with respect to such Notes shall be computed on the basis of the aggregate principal amount of the Notes (or specified portions thereof to the extent permitted
thereby) so surrendered. 
 (c) A Note shall be deemed to have been converted immediately prior to the close of business on the date (the
“Conversion Date”) that the Holder has complied with the requirements set forth in subsection (b) above. Except as set forth in Section 14.03(b) and Section 14.07(a), the Company shall deliver the consideration due in respect
of the Conversion Obligation, including the Interest Make-Whole Payment, on the third Business Day immediately following the relevant Conversion Date, if the Company elects Physical Settlement, or on the third Business Day immediately following the
last Trading Day of the Observation Period, in the case of any other Settlement Method. If any shares of Common Stock are due to converting Holders, the Company shall issue or cause to be issued, and deliver to the Conversion Agent or to such
Holder, or such Holder’s nominee or nominees, certificates or a book-entry transfer through the Depositary for the full number of shares of Common Stock to which such Holder shall be entitled in satisfaction of the Company’s Conversion
Obligation together with any Interest Make-Whole Payment, if applicable. 
 (d) In case any Physical Note shall be surrendered for partial
conversion, the Company shall execute and the Trustee shall authenticate and deliver to or upon the written order of the Holder of the Note so surrendered a new Note or Notes in authorized denominations in an aggregate principal amount equal to the
unconverted portion of the surrendered Note, without payment of any service charge by the converting Holder but, if required by the Company or Trustee, with payment of a sum sufficient to cover any documentary, stamp or similar issue or transfer tax
or similar governmental charge required by law or that may be imposed in connection therewith as a result of the name of the Holder of the new Notes issued upon such conversion being different from the name of the Holder of the old Notes surrendered
for such conversion. 
 (e) If a Holder submits a Note for conversion, the Company shall pay any documentary, stamp or similar issue or
transfer tax due on the issue of any shares of Common Stock upon conversion, unless the tax is due because the Holder requests such shares to be issued in a name other than the Holder’s name, in which case the Holder shall pay that tax. The
Company shall work directly with its stock transfer agent to effect any delivery of Common Stock in connection 

  
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with a conversion. The Conversion Agent may refuse to deliver the certificates representing the shares of Common Stock being issued in a name other than the Holder’s name until the Trustee
receives a sum sufficient to pay any tax that is due by such Holder in accordance with the immediately preceding sentence. 
 (f) Except as
provided in Section 14.04, no adjustment shall be made for dividends on any shares of Common Stock issued upon the conversion of any Note as provided in this Article 14. 

(g) Upon the conversion of an interest in a Global Note, the Trustee, or the Custodian (if other than the Trustee) at the direction of the
Trustee, shall make a notation on such Global Note as to the reduction in the principal amount represented thereby. The Company shall notify the Trustee in writing of any conversion of Notes effected through any Conversion Agent other than the
Trustee. 
 (h) Upon conversion, a Holder shall not receive any separate cash payment for accrued and unpaid interest, if any, except as set
forth below and except for the Interest Make-Whole Payment, if applicable. The Company’s settlement of the full Conversion Obligation shall be deemed to satisfy in full its obligation to pay the principal amount of the Note and accrued and
unpaid interest, if any, to, but excluding, the relevant Conversion Date. As a result, accrued and unpaid interest, if any, to, but excluding, the relevant Conversion Date shall be deemed to be paid in full rather than cancelled, extinguished or
forfeited. Upon a conversion of Notes into a combination of cash and shares of Common Stock, accrued and unpaid interest will be deemed to be paid first out of the cash paid upon such conversion. Notwithstanding the foregoing, if Notes are converted
after the close of business on a Regular Record Date and prior to the open of business on the corresponding Interest Payment Date, Holders of such Notes as of the close of business on such Regular Record Date will receive the full amount of interest
payable on such Notes on the corresponding Interest Payment Date notwithstanding the conversion. Notes surrendered for conversion during the period from the close of business on any Regular Record Date to the open of business on the immediately
following Interest Payment Date must be accompanied by funds equal to the amount of interest payable on the Notes so converted; provided that no such payment shall be required (1) for conversions after the close of business on the
Regular Record Date immediately preceding the Maturity Date; (2) if the Company has specified a Fundamental Change Repurchase Date that is after a Regular Record Date and on or prior to the Business Day immediately following the corresponding
Interest Payment Date; (3) for Notes in respect of which an Interest Make-Whole Payment is payable upon conversion; or (4) to the extent of any Defaulted Amounts, if any Defaulted Amounts exists at the time of conversion with respect to
such Note. Therefore, for the avoidance of doubt, all Holders of record after the close of business on the Regular Record Date immediately preceding the Maturity Date, any Fundamental Change Repurchase Date described in clause (2) of the
immediately preceding sentence and any Interest Make-Whole Payment upon conversion described in clause (3) of the immediately preceding sentence shall receive the full interest payment in cash due on the Maturity Date or other applicable
Interest Payment Date regardless of whether their Notes have been converted following such Regular Record Date. 
 (i) The Person in whose
name the shares of Common Stock shall be issuable upon conversion shall be treated as a stockholder of record as of the close of business on the relevant 

  
 67 

 
Conversion Date (if the Company elects to satisfy the related Conversion Obligation by Physical Settlement) or the last Trading Day of the relevant Observation Period (if the Company elects to
satisfy the related Conversion Obligation by Combination Settlement), as the case may be. Upon a conversion of Notes, such Person shall no longer be a Holder of such Notes surrendered for conversion. 

(j) The Company shall not issue any fractional share of Common Stock upon conversion of the Notes and shall instead pay cash in lieu of
delivering any fractional share of Common Stock issuable upon conversion based on the Daily VWAP for the relevant Conversion Date (in the case of Physical Settlement) or based on the Daily VWAP for the last Trading Day of the relevant Observation
Period (in the case of Combination Settlement). For each Note surrendered for conversion, if the Company has elected Combination Settlement, the full number of shares that shall be issued upon conversion thereof shall be computed on the basis of the
aggregate Daily Settlement Amounts for the relevant Observation Period and any fractional shares remaining after such computation shall be paid in cash. 

Section 14.03. Increased Conversion Rate Applicable to Certain Notes Surrendered in Connection with Make-Whole Fundamental
Changes. (a) If a Make-Whole Fundamental Change occurs or becomes effective prior to the Maturity Date and a Holder elects to convert its Notes in connection with such Make-Whole Fundamental Change, the Company shall, under the
circumstances described below, increase the Conversion Rate for the Notes so surrendered for conversion by a number of additional shares of Common Stock (the “Additional Shares”), as described below. A conversion of Notes shall be
deemed for these purposes to be “in connection with” such Make-Whole Fundamental Change if the relevant Notice of Conversion is received by the Conversion Agent from, and including, the Effective Date of the Make-Whole Fundamental Change
up to, and including, the Business Day immediately prior to the related Fundamental Change Repurchase Date (or, in the case of a Make-Whole Fundamental Change that would have been a Fundamental Change but for the proviso in clause (b) of
the definition thereof, the 35th Trading Day immediately following the Effective Date of such Make-Whole Fundamental Change) (such period, the “Make-Whole Fundamental Change Period”). 

(b) Upon surrender of Notes for conversion in connection with a Make-Whole Fundamental Change pursuant to Section 14.01(b)(iii), the Company
shall, at its option, satisfy the related Conversion Obligation by Physical Settlement, Cash Settlement or Combination Settlement in accordance with Section 14.02; provided, however, that if, at the effective time of a Make-Whole
Fundamental Change described in clause (b) of the definition of Fundamental Change, the Reference Property following such Make-Whole Fundamental Change is composed entirely of cash, for any conversion of Notes following the Effective Date of
such Make-Whole Fundamental Change, the Conversion Obligation shall be calculated based solely on the Stock Price for the transaction and shall be deemed to be an amount of cash per $1,000 principal amount of converted Notes equal to the Conversion
Rate (including any adjustment for Additional Shares), multiplied by such Stock Price. In such event, the Conversion Obligation shall be paid to Holders in cash on the third Business Day following the Conversion Date. The Company shall notify
in writing the Holders of Notes, the Trustee and the Conversion Agent (if other than the Trustee) of the Effective Date of any Make-Whole Fundamental Change no later than five Business Days after such Effective Date. 

  
 68 

 (c) The number of Additional Shares, if any, by which the Conversion Rate shall be increased
shall be determined by reference to the table below, based on the date on which the Make-Whole Fundamental Change occurs or becomes effective (the “Effective Date”) and the price (the “Stock Price”) paid (or deemed
to be paid) per share of the Common Stock in the Make-Whole Fundamental Change. If the holders of the Common Stock receive in exchange for their Common Stock only cash in a Make-Whole Fundamental Change described in clause (b) of the definition
of Fundamental Change, the Stock Price shall be the cash amount paid per share. Otherwise, the Stock Price shall be the average of the Last Reported Sale Prices of the Common Stock over the five consecutive Trading Day period ending on, and
including, the Trading Day immediately preceding the Effective Date of the Make-Whole Fundamental Change. The Board of Directors shall make appropriate adjustments to the Stock Price, in its good faith determination, to account for any adjustment to
the Conversion Rate that becomes effective, or any event requiring an adjustment to the Conversion Rate where the Ex-Dividend Date, Effective Date (as such term is used in Section 14.04) or expiration
date of the event occurs during such five consecutive Trading Day period. 
 (d) The Stock Prices set forth in the column headings of the
table below shall be adjusted as of any date on which the Conversion Rate of the Notes is otherwise adjusted. The adjusted Stock Prices shall equal the Stock Prices applicable immediately prior to such adjustment, multiplied by a fraction,
the numerator of which is the Conversion Rate immediately prior to such adjustment giving rise to the Stock Price adjustment and the denominator of which is the Conversion Rate as so adjusted. The number of Additional Shares set forth in the table
below shall be adjusted in the same manner and at the same time as the Conversion Rate as set forth in Section 14.04. 
 (e) The
following table sets forth the number of Additional Shares of Common Stock by which the Conversion Rate shall be increased per $1,000 principal amount of Notes pursuant to this Section 14.03 for each Stock Price and Effective Date set forth
below: 
  

																																									
	 	  	Stock Price	 
	 Effective Date
	  	$9.71	 	  	$11.00	 	  	$12.14	 	  	$15.00	 	  	$17.50	 	  	$20.00	 	  	$25.00	 	  	$30.00	 	  	$35.00	 	  	$50.00	 
	 December 21, 2016
	  	 	20.5973	  	  	 	17.1847	  	  	 	14.0627	  	  	 	9.1041	  	  	 	6.5623	  	  	 	4.8628	  	  	 	2.7603	  	  	 	1.4354	  	  	 	0.4885	  	  	 	0.0000	  
	 December 15, 2017
	  	 	20.5973	  	  	 	15.7800	  	  	 	12.6888	  	  	 	7.9827	  	  	 	5.6882	  	  	 	4.1965	  	  	 	2.3793	  	  	 	1.2372	  	  	 	0.4209	  	  	 	0.0000	  
	 December 15, 2018
	  	 	20.5973	  	  	 	13.9598	  	  	 	10.8927	  	  	 	6.5211	  	  	 	4.5606	  	  	 	3.3446	  	  	 	1.8945	  	  	 	0.9846	  	  	 	0.3342	  	  	 	0.0000	  
	 December 15, 2019
	  	 	20.5973	  	  	 	12.1576	  	  	 	8.9530	  	  	 	4.8562	  	  	 	3.2894	  	  	 	2.4022	  	  	 	1.3781	  	  	 	0.7337	  	  	 	0.2731	  	  	 	0.0000	  
	 December 15, 2020
	  	 	20.5973	  	  	 	10.2109	  	  	 	6.5268	  	  	 	2.7341	  	  	 	1.7528	  	  	 	1.2981	  	  	 	0.7782	  	  	 	0.4424	  	  	 	0.2025	  	  	 	0.0000	  
	 December 15, 2021
	  	 	20.5973	  	  	 	8.5198	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  	  	 	0.0000	  

 The exact Stock Prices and Effective Dates may not be set forth in the table above, in which case: 

(i) if the Stock Price is between two Stock Prices in the table above or the Effective Date is between two Effective Dates in
the table, the number of Additional Shares shall be determined by a straight-line interpolation between the number of Additional Shares set forth for the higher and lower Stock Prices and the earlier and later Effective Dates, as applicable, based
on a 365-day year; 

  
 69 

 (ii) if the Stock Price is greater than $50.00 per share (subject to adjustment
in the same manner as the Stock Prices set forth in the column headings of the table above pursuant to subsection (d) above), no Additional Shares shall be added to the Conversion Rate; and 

(iii) if the Stock Price is less than $9.71 per share (subject to adjustment in the same manner as the Stock Prices set forth
in the column headings of the table above pursuant to subsection (d) above), no Additional Shares shall be added to the Conversion Rate. 

Notwithstanding the foregoing, in no event shall the Conversion Rate per $1,000 principal amount of Notes exceed 102.9866 shares of Common Stock, subject to
adjustment in the same manner as the Conversion Rate pursuant to Section 14.04. 
 (f) Nothing in this Section 14.03 shall prevent
an adjustment to the Conversion Rate pursuant to Section 14.04 in respect of a Make-Whole Fundamental Change. 
 Section 14.04.
Adjustment of Conversion Rate. The Conversion Rate shall be adjusted from time to time by the Company if any of the following events occurs, except that the Company shall not make any adjustments to the Conversion Rate if Holders of the Notes
participate (other than in the case of a share split or share combination or a tender or exchange offer), at the same time and upon the same terms as holders of the Common Stock and solely as a result of holding the Notes, in any of the transactions
described in this Section 14.04, without having to convert their Notes, as if they held a number of shares of Common Stock equal to the Conversion Rate, multiplied by the principal amount (expressed in thousands) of Notes held by such
Holder. 
 (a) If the Company exclusively issues shares of Common Stock as a dividend or distribution on shares of the Common Stock, or if
the Company effects a share split or share combination, the Conversion Rate shall be adjusted based on the following formula: 
  

									
		 	CR’ = CR0	 	×	 	   OS’  
	  	
		 	 	 	  OS0  	  	

  

					
	where,	  		    	
			
	CR0	  	=	    	the Conversion Rate in effect immediately prior to the open of business on the Ex-Dividend Date of such dividend or distribution, or immediately prior to the open of business on the Effective
Date of such share split or share combination, as applicable;
			
	CR’	  	=	    	the Conversion Rate in effect immediately after the open of business on such Ex-Dividend Date or Effective Date;
			
	OS0	  	=	    	the number of shares of Common Stock outstanding immediately prior to the open of business on such Ex-Dividend Date or Effective Date; and
			
	OS’	  	=	    	the number of shares of Common Stock outstanding immediately after giving effect to such dividend, distribution, share split or share combination.

  
 70 

 Any adjustment made under this Section 14.04(a) shall become effective immediately after the open of business on
the Ex-Dividend Date for such dividend or distribution, or immediately after the open of business on the Effective Date for such share split or share combination, as applicable. If any dividend or distribution
of the type described in this Section 14.04(a) is declared but not so paid or made, the Conversion Rate shall be immediately readjusted, effective as of the date the Board of Directors determines not to pay such dividend or distribution, to the
Conversion Rate that would then be in effect if such dividend or distribution had not been declared. 
 (b) If the Company issues to all or
substantially all holders of the Common Stock any rights, options or warrants entitling them, for a period of not more than 45 calendar days after the announcement date of such issuance, to subscribe for or purchase shares of the Common Stock at a
price per share that is less than the average of the Last Reported Sale Prices of the Common Stock for the 10 consecutive Trading Day period ending on, and including, the Trading Day immediately preceding the date of announcement of such issuance,
the Conversion Rate shall be increased based on the following formula: 
  

									
		 	CR’ = CR0	 	×	 	 OS0 + X
	  	
		 	 	 	OS0 + Y	  	

  

					
	where,	  		    	
			
	CR0	  	=	    	the Conversion Rate in effect immediately prior to the open of business on the Ex-Dividend Date for such issuance;
			
	CR’	  	=	    	the Conversion Rate in effect immediately after the open of business on such Ex-Dividend Date;
			
	OS0	  	=	    	the number of shares of Common Stock outstanding immediately prior to the open of business on such Ex-Dividend Date;
			
	X	  	=	    	the total number of shares of Common Stock issuable pursuant to such rights, options or warrants; and
			
	Y	  	=	    	the number of shares of Common Stock equal to the aggregate price payable to exercise such rights, options or warrants, divided by the average of the Last Reported Sale Prices of the Common Stock over the 10 consecutive
Trading Day period ending on, and including, the Trading Day immediately preceding the date of announcement of the issuance of such rights, options or warrants.

 Any increase made under this Section 14.04(b) shall be made successively whenever any such rights, options or warrants are
issued and shall become effective immediately after the open of business on the Ex-Dividend Date for such issuance. To the extent that shares of the Common Stock are not delivered after the expiration of such
rights, options or warrants, the Conversion 

  
 71 

 
Rate shall be decreased to the Conversion Rate that would then be in effect had the increase with respect to the issuance of such rights, options or warrants been made on the basis of delivery of
only the number of shares of Common Stock actually delivered. If such rights, options or warrants are not so issued or if no such rights, options or warrants are exercised prior to their expiration, the Conversion Rate shall be decreased to the
Conversion Rate that would then be in effect if such Ex-Dividend Date for such issuance had not occurred. 

For purposes of this Section 14.04(b) and for the purpose of Section 14.01(b)(ii)(A), in determining whether any rights, options or warrants
entitle the holders to subscribe for or purchase shares of the Common Stock at less than such average of the Last Reported Sale Prices of the Common Stock for the 10 consecutive Trading Day period ending on, and including, the Trading Day
immediately preceding the date of announcement of such issuance, and in determining the aggregate offering price of such shares of Common Stock, there shall be taken into account any consideration received by the Company for such rights, options or
warrants and any amount payable on exercise or conversion thereof, the value of such consideration, if other than cash, to be determined by the Board of Directors. 

(c) If the Company distributes shares of its Capital Stock, evidences of its indebtedness, other assets or property of the Company or rights,
options or warrants to acquire its Capital Stock or other securities, to all or substantially all holders of the Common Stock, excluding (i) dividends, distributions or issuances as to which an adjustment was effected pursuant to Section
14.04(a) or Section 14.04(b), (ii) rights issued under a stockholder rights plan (except as otherwise provided in Section 14.11), (iii) dividends or distributions paid exclusively in cash as to which the provisions set forth in Section 14.04(d)
shall apply, (iv) distributions of Reference Property issued in exchange for Common Stock in a Common Stock Change Event, and (v) Spin-Offs as to which the provisions set forth below in this Section 14.04(c) shall apply (any of such shares
of Capital Stock, evidences of indebtedness, other assets or property or rights, options or warrants to acquire the Company’s Capital Stock or other securities, the “Distributed Property”), then the Conversion Rate shall be
increased based on the following formula: 
  

									
		 	CR’ = CR0	 	×	 	
  SP0  
	  	
		 	 	 	SP0 – FMV	  	

  

					
	where,	  		    	
			
	CR0	  	=	    	the Conversion Rate in effect immediately prior to the open of business on the Ex-Dividend Date for such distribution;
			
	CR’	  	=	    	the Conversion Rate in effect immediately after the open of business on the Ex-Dividend Date for such distribution;
			
	SP0	  	=	    	the average of the Last Reported Sale Prices of the Common Stock over the 10 consecutive Trading Day period ending on, and including, the Trading Day immediately preceding the Ex-Dividend Date
for such distribution; and
			
	FMV	  	=	    	the fair market value (as determined by the Board of Directors) of the Distributed Property with respect to each outstanding share of the Common Stock on the Ex-Dividend Date for such
distribution.

  
 72 

 Any increase made under the portion of this Section 14.04(c) above shall become effective immediately after the
open of business on the Ex-Dividend Date for such distribution. If such distribution is not so paid or made, the Conversion Rate shall be decreased to the Conversion Rate that would then be in effect if such
distribution had not been declared. Notwithstanding the foregoing, if “FMV” (as defined above) is equal to or greater than “SP0” (as defined above), then in lieu of the
foregoing increase, each Holder of a Note shall receive, in respect of each $1,000 principal amount of Notes it holds, at the same time and upon the same terms as holders of the Common Stock receive the Distributed Property, the amount and kind of
Distributed Property such Holder would have received if such Holder owned a number of shares of Common Stock equal to the Conversion Rate in effect on the Ex-Dividend Date for the distribution. If the Board of
Directors determines the “FMV” (as defined above) of any distribution for purposes of this Section 14.04(c) by reference to the actual or when-issued trading market for any securities, it shall in doing so consider the prices in such
market over the same period used in computing the Last Reported Sale Prices of the Common Stock over the 10 consecutive Trading Day period ending on, and including, the Trading Day immediately preceding the
Ex-Dividend Date for such distribution. 
 With respect to an adjustment pursuant to this Section
14.04(c) where there has been a payment of a dividend or other distribution on the Common Stock of shares of Capital Stock of any class or series, or similar equity interest, of or relating to any of the Company’s Subsidiaries or other business
units, that are, or, when issued, will be, listed or admitted for trading on a U.S. national securities exchange (a “Spin-Off”), the Conversion Rate shall be increased based on the following
formula: 
  

									
		 	CR’ = CR0	 	×	 	 FMV0 + MP0
	  	
		 	 	 	  MP0  	  	

  

					
	where,	  		    	
			
	CR0	  	=	    	the Conversion Rate in effect immediately prior to the end of the Valuation Period;
			
	CR’	  	=	    	the Conversion Rate in effect immediately after the end of the Valuation Period;
			
	FMV0	  	=	    	the average of the Last Reported Sale Prices of the Capital Stock or similar equity interest distributed to holders of the Common Stock applicable to one share of the Common Stock (determined by reference to the definition of Last
Reported Sale Price as set forth in Section 1.01 as if references therein to Common Stock were to such Capital Stock or similar equity interest) over the first 10 consecutive Trading Day period after, and including, the Ex-Dividend Date of the Spin-Off (the “Valuation Period”); provided that if there is no last reported sale price of the Capital Stock or similar equity
interest distributed to holders of Common Stock on such Ex-Dividend Date, the Valuation Period shall be the first ten consecutive Trading Day period after, and including the first date such Last Reported Sale
Price is available; and
			
	MP0	  	=	    	the average of the Last Reported Sale Prices of the Common Stock over the Valuation Period.

  
 73 

 The increase to the Conversion Rate under the preceding paragraph shall occur at the close of business on the
last Trading Day of the Valuation Period; provided that (x) in respect of any conversion of Notes for which Physical Settlement is applicable, if the relevant Conversion Date occurs during the Valuation Period, references in the portion
of this Section 14.04(c) related to Spin-Offs shall be deemed replaced with such lesser number of Trading Days as have elapsed between the Ex-Dividend Date for such
Spin-Off and such Conversion Date in determining the Conversion Rate and (y) in respect of any conversion of Notes for which Cash Settlement or Combination Settlement is applicable, subject to the
immediately succeeding sentence, for any Trading Day that falls within the relevant Observation Period for such conversion and within the Valuation Period, the reference to “10” in the preceding paragraph shall be deemed replaced with such
lesser number of Trading Days as have elapsed between the Ex-Dividend Date for such Spin-Off and such Trading Day in determining the Conversion Rate as of such Trading
Day. In addition, if the Ex-Dividend Date for such Spin-Off is after the 10th Trading Day immediately preceding, and including, the end of any Observation Period in
respect of a conversion of Notes, references to “10” or “10th” in the preceding paragraph and this paragraph shall be deemed to be replaced, solely in respect of that conversion of Notes, with such lesser number of Trading Days
as have elapsed from, and including, the Ex-Dividend Date for such Spin-Off to, and including, the last Trading Day of such Observation Period. If the distribution
constituting the Spin-Off is not so paid or made, the Conversion Rate shall be decreased to the Conversion Rate that would be in effect if such distribution had not been declared. 

For purposes of this Section 14.04(c) (and subject in all respect to Section 14.11), rights, options or warrants distributed by the
Company to all holders of the Common Stock entitling them to subscribe for or purchase shares of the Company’s Capital Stock, including Common Stock (either initially or under certain circumstances), which rights, options or warrants, until the
occurrence of a specified event or events (“Trigger Event”): (i) are deemed to be transferred with such shares of the Common Stock; (ii) are not exercisable; and (iii) are also issued in respect of future issuances of the
Common Stock, shall be deemed not to have been distributed for purposes of this Section 14.04(c) (and no adjustment to the Conversion Rate under this Section 14.04(c) will be required) until the occurrence of the earliest Trigger Event, whereupon
such rights, options or warrants shall be deemed to have been distributed and an appropriate adjustment (if any is required) to the Conversion Rate shall be made under this Section 14.04(c). If any such right, option or warrant, including any such
existing rights, options or warrants distributed prior to the date of this Indenture, are subject to events, upon the occurrence of which such rights, options or warrants become exercisable to purchase different securities, evidences of indebtedness
or other assets, then the date of the occurrence of any and each such event shall be deemed to be the date of distribution and Ex-Dividend Date with respect to new rights, options or warrants with such rights
(in which case the existing rights, options or warrants shall be deemed to terminate and expire on such date without exercise by any of the holders thereof). In addition, in the event of any distribution (or deemed distribution) of rights, options
or warrants, 

  
 74 

 
or any Trigger Event or other event (of the type described in the immediately preceding sentence) with respect thereto that was counted for purposes of calculating a distribution amount for which
an adjustment to the Conversion Rate under this Section 14.04(c) was made, (1) in the case of any such rights, options or warrants that shall all have been redeemed or purchased without exercise by any holders thereof, upon such final
redemption or purchase (x) the Conversion Rate shall be readjusted as if such rights, options or warrants had not been issued and (y) the Conversion Rate shall then again be readjusted to give effect to such distribution, deemed
distribution or Trigger Event, as the case may be, as though it were a cash distribution, equal to the per share redemption or purchase price received by a holder or holders of Common Stock with respect to such rights, options or warrants (assuming
such holder had retained such rights, options or warrants), made to all holders of Common Stock as of the date of such redemption or purchase, and (2) in the case of such rights, options or warrants that shall have expired or been terminated
without exercise by any holders thereof, the Conversion Rate shall be readjusted as if such rights, options and warrants had not been issued. 

For purposes of Section 14.04(a), Section 14.04(b) and this Section 14.04(c), if any dividend or distribution to which this
Section 14.04(c) is applicable also includes one or both of: 
 (A) a dividend or distribution of shares of Common Stock to which
Section 14.04(a) is applicable (the “Clause A Distribution”); or 
 (B) a dividend or distribution of rights, options or
warrants to which Section 14.04(b) is applicable (the “Clause B Distribution”), 
 then, in either case, (1) such dividend or
distribution, other than the Clause A Distribution and the Clause B Distribution, shall be deemed to be a dividend or distribution to which this Section 14.04(c) is applicable (the “Clause C Distribution”) and any Conversion Rate
adjustment required by this Section 14.04(c) with respect to such Clause C Distribution shall then be made, and (2) the Clause A Distribution and Clause B Distribution shall be deemed to immediately follow the Clause C Distribution and any
Conversion Rate adjustment required by Section 14.04(a) and Section 14.04(b) with respect thereto shall then be made, except that, if determined by the Company (I) the “Ex-Dividend Date” of the
Clause A Distribution and the Clause B Distribution shall be deemed to be the Ex-Dividend Date of the Clause C Distribution and (II) any shares of Common Stock included in the Clause A Distribution or
Clause B Distribution shall be deemed not to be “outstanding immediately prior to the open of business on such Ex-Dividend Date or Effective Date” within the meaning of Section 14.04(a) or
“outstanding immediately prior to the open of business on such Ex-Dividend Date” within the meaning of Section 14.04(b). 

  
 75 

 (d) If any cash dividend or distribution is made to all or substantially all holders of the
Common Stock, the Conversion Rate shall be adjusted based on the following formula: 
  

									
		 	CR’ = CR0	 	× 	 	  SP0  	  	
		 	 	 	SP0 – C 	  	

  

					
	where,	  		    	
			
	CR0	  	=	    	the Conversion Rate in effect immediately prior to the open of business on the Ex-Dividend Date for such dividend or distribution;
			
	CR’	  	=	    	the Conversion Rate in effect immediately after the open of business on the Ex-Dividend Date for such dividend or distribution;
			
	SP0	  	=	    	the Last Reported Sale Price of the Common Stock on the Trading Day immediately preceding the Ex-Dividend Date for such dividend or distribution; and
			
	C	  	=	    	the amount in cash per share the Company distributes to all or substantially all holders of the Common Stock.

 Any increase pursuant to this Section 14.04(d) shall become effective immediately after the open of business on the Ex-Dividend Date for such dividend or distribution. If such dividend or distribution is not so paid, the Conversion Rate shall be decreased, effective as of the date the Board of Directors determines not to make or
pay such dividend or distribution, to be the Conversion Rate that would then be in effect if such dividend or distribution had not been declared. Notwithstanding the foregoing, if “C” (as defined above) is equal to or greater than “SP0” (as defined above), then, in lieu of the foregoing increase, each Holder of a Note shall receive, for each $1,000 principal amount of Notes it holds, at the same time and upon the same terms
as holders of shares of the Common Stock, the amount of cash that such Holder would have received if such Holder owned a number of shares of Common Stock equal to the Conversion Rate in effect on the
Ex-Dividend Date for such cash dividend or distribution. 
 (e) If the Company or any of its
Subsidiaries make a payment in respect of a tender or exchange offer for the Common Stock (other than odd-lot tender offers), to the extent that the cash and value of any other consideration included in the
payment per share of the Common Stock exceeds the average of the Last Reported Sale Prices of the Common Stock over the 10 consecutive Trading Day period commencing on, and including, the Trading Day next succeeding the last date on which tenders or
exchanges may be made pursuant to such tender or exchange offer, the Conversion Rate shall be increased based on the following formula: 
  

									
		 	CR’ = CR0	 	× 	 	AC + (SP’×OS’) 	  	
		 	 	 	  OS0 × SP’  	  	

  

					
	where,	  		    	
			
	CR0	  	=	    	the Conversion Rate in effect immediately prior to the close of business on the 10th Trading Day immediately following, and including, the Trading Day next succeeding the date such tender or exchange offer expires;
			
	CR’	  	=	    	the Conversion Rate in effect immediately after the close of business on the 10th Trading Day immediately following, and including, the Trading Day next succeeding the date such tender or exchange offer
expires;

  
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	AC	  	=	    	the aggregate value of all cash and any other consideration (as determined by the Board of Directors) paid or payable for shares of Common Stock purchased in such tender or exchange offer;
			
	OS0	  	=	    	the number of shares of Common Stock outstanding immediately prior to the date such tender or exchange offer expires (prior to giving effect to the purchase of all shares of Common Stock accepted for purchase or exchange in such
tender or exchange offer);
			
	OS’	  	=	    	the number of shares of Common Stock outstanding immediately after the date such tender or exchange offer expires (after giving effect to the purchase of all shares of Common Stock accepted for purchase or exchange in such tender or
exchange offer); and
			
	SP’	  	=	    	the average of the Last Reported Sale Prices of the Common Stock over the 10 consecutive Trading Day period commencing on, and including, the Trading Day next succeeding the date such tender or exchange offer expires.

 The increase to the Conversion Rate under this Section 14.04(e) shall occur at the close of business on the 10th Trading Day
immediately following, and including, the Trading Day next succeeding the date such tender or exchange offer expires; provided that (x) in respect of any conversion of Notes for which Physical Settlement is applicable, if the relevant
Conversion Date occurs during the 10 Trading Days immediately following, and including, the Trading Day next succeeding the expiration date of any tender or exchange offer, references to “10” or “10th” in the preceding paragraph
shall be deemed replaced with such lesser number of Trading Days as have elapsed between the expiration date of such tender or exchange offer and such Conversion Date in determining the conversion rate and (y) in respect of any conversion of
Notes for which Cash Settlement or Combination Settlement is applicable, subject to the immediately succeeding sentence, for any Trading Day that falls within the relevant Observation Period for such conversion and within the 10 Trading Days
immediately following, and including, the expiration date of any tender or exchange offer, references in this Section 14.04(e) to “10” or “10th” in the preceding paragraph shall be deemed replaced with such lesser number of
Trading Days as have elapsed between the date that such tender or exchange offer expires and such Trading Day in determining the Conversion Rate as of such Trading Day. In addition, if the Trading Day next succeeding the date such tender or exchange
offer expires is after the 10th Trading Day immediately preceding, and including, the end of any Observation Period in respect of a conversion of Notes, references to “10” or “10th” in the preceding paragraph and this paragraph
shall be deemed to be replaced, solely in respect of that conversion of Notes, with such lesser number of Trading Days as have elapsed from, and including, the Trading Day next succeeding the date such tender or exchange offer expires to, and
including, the last Trading Day of such Observation Period. If the Company is obligated to purchase shares of the Common Stock pursuant to any such tender or exchange offer described in this Section 14.04(e) but is permanently prevented by
applicable law from effecting any such purchase or all such purchases are rescinded, the applicable Conversion Rate shall be decreased to be the Conversion Rate that would then be in effect if such tender or exchange offer had not been made or had
been made only in respect of the purchases that have been effected. 

  
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 (f) Notwithstanding this Section 14.04 or any other provision of this Indenture or the
Notes, if: (i) a Conversion Rate adjustment for any event becomes effective on any Ex-Dividend Date; (ii) a Note is to be converted pursuant to Physical Settlement or Combination Settlement;
(iii) the Conversion Date for such conversion (in the case of Physical Settlement) or any Trading Day in the Observation Period for such conversion (in the case of Combination Settlement) occurs on or after such
Ex-Dividend Date and on or before the related Record Date; and (iv) the Holder would be treated, on such Record Date, as the record holder of such shares of Common Stock based on a Conversion Rate that is
adjusted for such event on such basis, then, such Conversion Rate adjustment will not be given effect for such conversion (in the case of Physical Settlement) or such Trading Day (in the case of Combination Settlement). Instead, such Holder shall be
treated as if such Holder were, as of such Record Date, the record owner of such shares of Common Stock on an unadjusted basis and will participate in such event. 

(g) Except as stated herein, the Company shall not adjust the Conversion Rate for the issuance of shares of the Common Stock or any securities
convertible into or exchangeable for shares of the Common Stock or the right to purchase shares of the Common Stock or such convertible or exchangeable securities. 

(h) In addition to those adjustments required by clauses (a), (b), (c), (d) and (e) of this Section 14.04, and to the extent
permitted by applicable law and subject to the applicable rules of any exchange on which any of the Company’s securities are then listed, the Company from time to time may (but is not required to) increase the Conversion Rate by any amount for
a period of at least 20 Business Days if the Board of Directors determines that such increase would be in the Company’s best interest. In addition, to the extent permitted by applicable law and subject to the applicable rules of any exchange on
which any of the Company’s securities are then listed, the Company may (but is not required to) increase the Conversion Rate to avoid or diminish any income tax to holders of Common Stock or rights to purchase Common Stock in connection with a
dividend or distribution of shares of Common Stock (or rights to acquire shares of Common Stock) or similar event. Whenever the Conversion Rate is increased pursuant to either of the preceding two sentences, the Company shall give to the Holder of
each Note at its last address appearing on the Note Register a notice of the increase at least 15 days prior to the date the increased Conversion Rate takes effect, and such notice shall state the increased Conversion Rate and the period during
which it will be in effect. 
 (i) Notwithstanding anything to the contrary in this Article 14, the Conversion Rate shall not be adjusted:

 (i) upon the issuance of Common Stock at a price below the Conversion Price or otherwise (other than any such issuance
described in Section 14.04(a), (b) or (c)); 
 (ii) upon the issuance of any shares of Common Stock pursuant to any present
or future plan providing for the reinvestment of dividends or interest payable on the Company’s securities and the investment of additional optional amounts in shares of Common Stock under any plan; 

(iii) upon the issuance of any shares of Common Stock or options or rights to purchase those shares pursuant to any present or
future employee, director or consultant benefit plan or program of or assumed by the Company or any of the Company’s Subsidiaries; 

  
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 (iv) upon the issuance of any shares of the Common Stock pursuant to any option,
warrant, right or exercisable, exchangeable or convertible security not described in clause (iii) of this subsection and outstanding as of the date the Notes were first issued; 

(v) for a third-party tender offer by any party other than a tender offer by one or more of the Company’s Subsidiaries as
described in Section 14.04(e) 
 (vi) upon the repurchase of any shares of the Common Stock pursuant to an open-market share
purchase program or other buy-back transaction, including structured or derivative transactions, that is not a tender offer or exchange offer of the kind described in Section 14.04(e); 

(vii) solely for a change in the par value of the Common Stock; or 

(viii) for accrued and unpaid interest, if any. 

(j) All calculations and other determinations under this Article 14 shall be made by the Company and shall be made to the nearest one-ten thousandth (1/10,000th) of a share. If an adjustment to the Conversion Rate otherwise required pursuant to clause (a), (b), (c), (d) or (e) of this Section 14.04 would result in a change of less
than 1% to the Conversion Rate, then, notwithstanding the foregoing, the Company may, at its election, defer and carry forward such adjustment, except that all such deferred adjustments must be given effect immediately upon the earliest to occur of
the following: (i) when all such deferred adjustments would result in an aggregate change of at least 1% to the Conversion Rate; (ii) the Conversion Date of, or any trading day of an Observation Period for, any Note; (iii) the date a
Fundamental Change or Make-Whole Fundamental Change occurs; and (iv) September 15, 2021. 
 (k) Whenever the Conversion Rate is
adjusted as herein provided, the Company shall promptly file with the Trustee (and the Conversion Agent if not the Trustee) an Officer’s Certificate setting forth the Conversion Rate after such adjustment and setting forth a brief statement of
the facts requiring such adjustment. Unless and until a Responsible Officer of the Trustee shall have received such Officer’s Certificate, the Trustee shall not be deemed to have knowledge of any adjustment of the Conversion Rate and may assume
without inquiry that the last Conversion Rate of which it has knowledge is still in effect. Promptly after delivery of such certificate, the Company shall prepare a notice of such adjustment of the Conversion Rate setting forth the adjusted
Conversion Rate and the date on which each adjustment becomes effective and shall give such notice of such adjustment of the Conversion Rate to each Holder at its last address appearing on the Note Register of this Indenture. Failure to deliver such
notice shall not affect the legality or validity of any such adjustment. 
 (l) For purposes of this Section 14.04, the number of
shares of Common Stock at any time outstanding shall not include shares of Common Stock held in the treasury of the Company so long as the Company does not pay any dividend or make any distribution on shares of Common Stock held in the treasury of
the Company, but shall include shares of Common Stock issuable in respect of scrip certificates issued in lieu of fractions of shares of Common Stock. 

  
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 (m) Notwithstanding anything to the contrary in this Article 14, certain listing standards of The
NASDAQ Global Select Market may limit the amount by which the Company may increase the Conversion Rate pursuant to the events described in clauses clause (b) through (e) of this Section 14.04 and as described in the Section 14.01(c). These
standards generally require the Company to obtain the approval of the Company’s stockholders before entering into certain transactions that potentially result in the issuance of 20% or more of the Common Stock outstanding at the time the Notes
are initially issued at an effective price per share less than the greater of book and market value per share on the date the Notes are initially issued (as adjusted in accordance with such standards for certain events such as stock splits, stock
dividends and similar events) unless the Company obtains stockholder approval of issuances in excess of such limitations. In accordance with these listing standards, these restrictions will apply at any time when the Notes are outstanding,
regardless of whether the Company then has a class of securities listed on The NASDAQ Global Select Market. Accordingly, in the event of an increase in the Conversion Rate above that would result in the Notes, in the aggregate, becoming convertible
into shares of Common Stock in violation of such limitations, the Company will, at its option, either obtain stockholder approval of such issuances or settle any Interest Make-Whole Payments in cash and/or deliver cash in lieu of any shares
otherwise deliverable upon conversions in excess of such limitations based on the Daily VWAP on each Trading Day of the relevant Observation Period in respect of which, in lieu of delivering shares of Common Stock, the Company shall deliver cash
pursuant to this Section 14.04(m). 
 Section 14.05. Adjustments of Prices. Whenever any provision of this Indenture
requires the Company to calculate the Last Reported Sale Prices, the Daily VWAPs, the Daily Conversion Values or the Daily Settlement Amounts over a span of multiple days (including an Observation Period and the period for determining the Stock
Price for purposes of a Make-Whole Fundamental Change), the Board of Directors shall make appropriate adjustments to each to account for any adjustment to the Conversion Rate that becomes effective, or any event requiring an adjustment to the
Conversion Rate as provided under Section 14.02 where the Ex-Dividend Date, Effective Date, effective time or expiration date, as the case may be, of the event occurs, at any time during the period when
the Last Reported Sale Prices, the Daily VWAPs, the Daily Conversion Values or the Daily Settlement Amounts are to be calculated. 
 For the
avoidance of doubt, the adjustments made pursuant to the foregoing paragraph will be made without duplication of any adjustment made pursuant to the provision set forth under Section 14.04. 

Section 14.06. Shares to Be Fully Paid. The Company shall provide, free from preemptive rights, out of its authorized but unissued
shares or shares held in treasury, sufficient shares of Common Stock to provide for conversion of the Notes from time to time as such Notes are presented for conversion (assuming delivery of the maximum number of Additional Shares pursuant to
Section 14.03 and that at the time of computation of such number of shares, all such Notes would be converted by a single Holder and that Physical Settlement were applicable). 

  
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 Section 14.07. Effect of Recapitalizations, Reclassifications and Changes of the Common
Stock. 
 (a) In the case of: 

(i) any recapitalization, reclassification or change of the Common Stock (other than a change to par value, or from par value
to no par value, or changes resulting from a subdivision or combination), 
 (ii) any consolidation, merger, combination or
similar transaction involving the Company, 
 (iii) any sale, lease or other transfer to a third party of the consolidated
assets of the Company and the Company’s Subsidiaries substantially as an entirety or 
 (iv) any statutory share
exchange, 
 in each case, as a result of which the Common Stock would be converted into, or exchanged for, shares, stock, other securities, other property
or assets (including cash or any combination thereof) (any such event, a “Common Stock Change Event”), then, at and after the effective time of such Common Stock Change Event, the Company or the successor or acquiring corporation,
as the case may be, will execute a supplemental indenture with the Trustee, providing that the right to convert each $1,000 principal amount of Notes shall be changed into a right to convert such principal amount of Notes into the kind and amount of
shares, shares of stock, other securities or other property or assets (including cash or any combination thereof) that a holder of a number of shares of Common Stock equal to the Conversion Rate immediately prior to such Common Stock Change Event
would have owned or been entitled to receive (the “Reference Property,” with each “unit of Reference Property” meaning the kind and amount of Reference Property that a holder of one share of Common Stock is entitled
to receive) upon such Common Stock Change Event and, prior to or at the effective time of such Common Stock Change Event, the Company or the successor or purchasing Person, as the case may be, shall execute with the Trustee a supplemental indenture
permitted under Section 10.01(h) providing for such change in the right to convert each $1,000 principal amount of Notes; provided, however, that at and after the effective time of the Common Stock Change Event (A) the Company
shall continue to have the right to determine the form of consideration to be paid or delivered, as the case may be, upon conversion of Notes in accordance with Section 14.02 and to elect to pay any Interest Make-Whole Payment in cash or shares
of Common Stock to the extent described under Section 14.01(c) and (B) (I) any amount payable in cash upon conversion of the Notes in accordance with Section 14.02 and Section 14.01(c) shall continue to be payable in cash, (II) any
shares of Common Stock that the Company would have been required to deliver upon conversion of the Notes in accordance with Section 14.02 shall instead be deliverable in the amount and type of Reference Property that a holder of that number of
shares of Common Stock would have been entitled to receive in such Common Stock Change Event, (III) the Daily VWAP shall be calculated based on the value of a unit of Reference Property and (IV) the conditions to conversion specified in
Section 14.04(b)(i), (ii), (iii) and (iv) shall be determined as if each reference to a share of Common Stock were instead to a unit of Reference Property. 

  
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 If the Common Stock Change Event causes the Common Stock to be converted into, or exchanged for,
the right to receive more than a single type of consideration (determined based in part upon any form of stockholder election), then (i) the Reference Property will be deemed to be (x) the weighted average of the types and amounts of
consideration received by the holders of Common Stock that affirmatively make such an election or (y) if no holders of Common Stock affirmatively make such an election, the types and amounts of consideration actually received by the holders of
Common Stock, and (ii) the unit of Reference Property for purposes of the immediately preceding paragraph shall refer to the consideration referred to in clause (i) attributable to one share of Common Stock. If the holders of the Common
Stock receive only cash in such Common Stock Change Event, then for all conversions for which the relevant Conversion Date occurs after the effective date of such Common Stock Change Event (A) the consideration due upon conversion of each
$1,000 principal amount of Notes shall be solely cash in an amount equal to the Conversion Rate in effect on the Conversion Date (as may be increased by any Additional Shares pursuant to Section 14.03), multiplied by the price paid per
share of Common Stock in such Common Stock Change Event and (B) the Company shall satisfy the Conversion Obligation by paying cash to converting Holders on or before the third Business Day immediately following the relevant Conversion Date. The
Company shall notify in writing Holders, the Trustee and the Conversion Agent (if other than the Trustee) of such weighted average as soon as practicable after such determination is made. 

The supplemental indenture described in the second immediately preceding paragraph shall provide for anti-dilution and other adjustments that
shall be as nearly equivalent as is possible to the adjustments provided for in this Article 14. If, in the case of any Common Stock Change Event, the Reference Property includes shares of stock, securities or other property or assets of a Person
other than the Company or the successor or purchasing corporation, as the case may be, in such Common Stock Change Event, then such supplemental indenture shall also be executed by such other Person and shall contain such additional provisions to
protect the interests of the Holders, including the right of Holders to require the Company to repurchase their Notes upon a Fundamental Change Article 15, as the Board of Directors shall reasonably consider necessary by reason of the
foregoing. 
 (b) When the Company executes a supplemental indenture pursuant to subsection (a) of this Section 14.07, the Company
shall promptly file with the Trustee an Officer’s Certificate briefly stating the reasons therefor, the kind or amount of cash, securities or property or asset that will comprise a unit of Reference Property after any such Common Stock Change
Event, any adjustment to be made with respect thereto and that all conditions precedent have been complied with, and shall promptly mail notice thereof to all Holders. The Company shall cause notice of the execution of such supplemental indenture to
be mailed to each Holder, at its address appearing on the Note Register provided for in this Indenture, within 20 days after execution thereof. Failure to deliver such notice shall not affect the legality or validity of such supplemental indenture.

 (c) The Company shall not become a party to any Common Stock Change Event unless its terms are consistent with this Section 14.07.
None of the foregoing provisions shall affect the right of a holder of Notes to convert its Notes into cash, shares of Common Stock or a combination of cash and shares of Common Stock, as applicable, as set forth in Section 14.01 and
Section 14.02 prior to the effective date of such Common Stock Change Event. 
 (d) The above provisions of this Section shall
similarly apply to successive Common Stock Change Events. 

  
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 Section 14.08. Certain Covenants. (a) The Company covenants that all shares of
Common Stock issued upon conversion of Notes will be fully paid and non-assessable by the Company and free from all taxes, liens and charges with respect to the issue thereof. 

(b) The Company covenants that, if any shares of Common Stock to be provided for the purpose of conversion of Notes hereunder require
registration with or approval of any governmental authority under any federal or state law before such shares of Common Stock may be validly issued upon conversion, the Company will, to the extent then permitted by the rules and interpretations of
the Commission, secure such registration or approval, as the case may be. 
 (c) The Company further covenants that if at any time the
Common Stock shall be listed on any national securities exchange or automated quotation system the Company will list and keep listed, so long as the Common Stock shall be so listed on such exchange or automated quotation system, any Common Stock
issuable upon conversion of the Notes. 
 Section 14.09. Responsibility of Trustee. The Trustee and any other Conversion Agent
shall not at any time be under any duty or responsibility to any Holder to determine the Conversion Rate (or any adjustment thereto) or whether any facts exist that may require any adjustment (including any increase) of the Conversion Rate, or with
respect to the nature or extent or calculation of any such adjustment when made, or with respect to the method employed, or herein or in any supplemental indenture provided to be employed, in making the same. The Trustee and any other Conversion
Agent shall not be accountable with respect to the validity or value (or the kind or amount) of any shares of Common Stock, or of any securities, property or cash that may at any time be issued or delivered upon the conversion of any Note; and the
Trustee and any other Conversion Agent make no representations with respect thereto. Neither the Trustee nor any Conversion Agent shall be responsible for any failure of the Company to issue, transfer or deliver any shares of Common Stock or stock
certificates or other securities or property or cash upon the surrender of any Note for the purpose of conversion or to comply with any of the duties, responsibilities or covenants of the Company contained in this Article. Without limiting the
generality of the foregoing, neither the Trustee nor any Conversion Agent shall be under any responsibility to determine the correctness of any provisions contained in any supplemental indenture entered into pursuant to Section 14.07 relating
either to the kind or amount of shares of stock or securities or property (including cash) receivable by Holders upon the conversion of their Notes after any event referred to in such Section 14.07 or to any adjustment to be made with respect
thereto, but, subject to the provisions of Section 7.01, may accept (without any independent investigation) as conclusive evidence of the correctness of any such provisions, and shall be protected in relying upon, the Officer’s Certificate
(which the Company shall be obligated to file with the Trustee prior to the execution of any such supplemental indenture) with respect thereto. Neither the Trustee nor the Conversion Agent shall be responsible for determining whether any event
contemplated by Section 14.01(b) has occurred that makes the Notes eligible for conversion or no longer eligible therefor until the 

  
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Company has delivered to the Trustee and the Conversion Agent the notices referred to in Section 14.01(b) with respect to the commencement or termination of such conversion rights, on which
notices the Trustee and the Conversion Agent may conclusively rely, and the Company agrees to deliver such notices to the Trustee and the Conversion Agent immediately after the occurrence of any such event or at such other times as shall be provided
for in Section 14.01(b). 
 Section 14.10. Notice to Holders Prior to Certain Actions. In case of any: 

(a) action by the Company or one of its Subsidiaries that would require an adjustment in the Conversion Rate pursuant to Section 14.04 or
Section 14.11; 
 (b) Common Stock Change Event; or 

(c) voluntary or involuntary dissolution, liquidation or winding-up of the Company or any of its
Subsidiaries; 
 then, in each case (unless notice of such event is otherwise required pursuant to another provision of this Indenture), the Company shall
promptly file with the Trustee and the Conversion Agent (if other than the Trustee) and to be given to each Holder, as promptly as possible but in any event at least 20 days prior to the applicable date hereinafter specified, a notice stating
(i) the date on which a record is to be taken for the purpose of such action by the Company or one of its Subsidiaries or, if a record is not to be taken, the date as of which the holders of Common Stock of record are to be determined for the
purposes of such action by the Company or one of its Subsidiaries, or (ii) the date on which such Common Stock Change Event, dissolution, liquidation or winding-up is expected to become effective or
occur, and the date as of which it is expected that holders of Common Stock of record shall be entitled to exchange their Common Stock for securities or other property deliverable upon such Common Stock Change Event, dissolution, liquidation or winding-up. Failure to give such notice, or any defect therein, shall not affect the legality or validity of such action by the Company or one of its Subsidiaries, Common Stock Change Event, dissolution, liquidation
or winding-up. 
 Whenever the Conversion Rate is adjusted pursuant to Section 14.04 or
Section 14.11, the Company shall promptly file with the Trustee and the Conversion Agent (if other than the Trustee) an Officer’s Certificate setting forth the Conversion Rate after such adjustment and setting forth a brief statement of
the facts requiring such adjustment. In the absence of an Officer’s Certificate being filed with the Trustee and the Conversion Agent (if other than the Trustee), the Trustee may assume without inquiry that the Conversion Rate has not been
adjusted and that the last Conversion Rate of which it has knowledge remains in effect. 
 Section 14.11. Stockholder Rights
Plans. If the Company has a stockholder rights plan in effect upon conversion of the Notes, each share of Common Stock, if any, issued upon such conversion shall be entitled to receive the appropriate number of rights, if any, and the
certificates representing the Common Stock issued upon such conversion shall bear such legends, if any, in each case as may be provided by the terms of any such stockholder rights plan, as the same may be amended from time to time. However, if,
prior to any conversion of Notes, the rights have separated from the shares of Common Stock in accordance with the provisions of the applicable stockholder rights plan, the Conversion Rate shall be adjusted at the time of

  
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separation as if the Company distributed to all or substantially all holders of the Common Stock Distributed Property as provided in Section 14.04(c), subject to readjustment in the event of the
expiration, termination or redemption of such rights. 
 Section 14.12. Exchange in Lieu of Conversion. Notwithstanding anything
herein to the contrary, when a Holder surrenders its Notes for conversion, the Company may, at its election (an “Exchange Election”), direct the Conversion Agent to surrender, on or prior to the second Business Day following the
Conversion Date, such Notes to a financial institution designated by the Company for exchange in lieu of conversion. In order to accept any Notes surrendered for conversion, the designated financial institution must agree to timely deliver, in
exchange for such Notes, the cash, shares of Common Stock or combination of cash and shares of Common Stock that would otherwise be due upon conversion pursuant to Section 14.02 due upon conversion, including the Interest Make-Whole Payment, if applicable (the “Conversion Consideration”), all as provided in this Article 14. If the Company makes an Exchange Election, the Company shall, by the close of business on the
second Business Day following the relevant Conversion Date, notify in writing the Trustee, the Conversion Agent (if other than the Trustee) and the Holder surrendering Notes for conversion that the Company has made the Exchange Election and the
Company shall notify the designated financial institution of the Settlement Method the Company has elected with respect to such conversion and the relevant deadline for delivery of the Conversion Consideration. 

Any Notes exchanged by the designated financial institution shall remain outstanding, subject to the applicable procedures of the Depositary.
If the designated financial institution agrees to accept any Notes for exchange but does not timely deliver the Conversion Consideration, or if such designated financial institution does not accept the Notes for exchange, the Company shall deliver
the Conversion Consideration due upon conversion to the converting Holder at the time and in the manner provided in this Article 14 as if the Company had not made an Exchange Election. 

The Company’s designation of a financial institution to which Notes may be submitted for exchange does not require such financial
institution to accept any Notes, in which case the notes shall be converted in the manner provided in this Article 14. The Company may, but is not obligated to, pay any consideration to, or otherwise enter into any agreement with, any designated
financial institution(s) for or with respect to such designation. 
 ARTICLE 15 

REPURCHASE OF NOTES AT OPTION OF
HOLDERS 
 Section 15.01. [Intentionally Omitted]  

Section 15.02. Repurchase at Option of Holders Upon a Fundamental Change. (a) If a Fundamental Change occurs at any
time prior to the Maturity Date, each Holder shall have the right, at such Holder’s option, to require the Company to repurchase for cash all of such Holder’s Notes, or any portion thereof that is equal to minimum denominations of $1,000
or an integral multiple of $1,000 in excess thereof, on the date (the “Fundamental Change Repurchase Date”) specified by the Company that is not less than 20 Business Days or more than 35

  
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Business Days following the date of the Fundamental Change Company Notice at a repurchase price equal to 100% of the principal amount thereof, plus accrued and unpaid interest thereon to,
but excluding, the Fundamental Change Repurchase Date (the “Fundamental Change Repurchase Price”), unless the Fundamental Change Repurchase Date falls after a Regular Record Date but on or prior to the Interest Payment Date to which
such Regular Record Date relates, in which case the Company shall instead pay the full amount of accrued and unpaid interest to Holders of record as of such Regular Record Date, and the Fundamental Change Repurchase Price shall be equal to 100% of
the principal amount of Notes to be repurchased pursuant to this Article 15. The Fundamental Change Repurchase Date shall be subject to postponement in order to allow the Company to comply with applicable law as a result of changes to such
applicable law occurring after the date of this Indenture. 
 (b) Repurchases of Notes under this Section 15.02 shall be made, at the
option of the Holder thereof, upon: 
 (i) delivery to the Paying Agent by a Holder of a duly completed notice (the
“Fundamental Change Repurchase Notice”) in the form set forth in Attachment 2 to the Form of Note attached hereto as Exhibit A, if the Notes are Physical Notes, or in compliance with the Depositary’s procedures for surrendering
interests in Global Notes, if the Notes are Global Notes, in each case on or before the close of business on the Business Day immediately preceding the Fundamental Change Repurchase Date; and 

(ii) delivery of the Notes, if the Notes are Physical Notes, to the Paying Agent at any time after delivery of the Fundamental
Change Repurchase Notice (together with all necessary endorsements for transfer) at the Corporate Trust Office of the Paying Agent, or book-entry transfer of the Notes, if the Notes are Global Notes, in compliance with the procedures of the
Depositary, in each case such delivery being a condition to receipt by the Holder of the Fundamental Change Repurchase Price therefor. 

The Fundamental Change Repurchase Notice in respect of any Notes to be repurchased shall state: 

(i) in the case of Physical Notes, the certificate numbers of the Notes to be delivered for repurchase; 

(ii) the portion of the principal amount of Notes to be repurchased, which must be $1,000 or an integral multiple thereof; and

 (iii) that the Notes are to be repurchased by the Company pursuant to the applicable provisions of the Notes and this
Indenture; 
 provided, however, that if the Notes are Global Notes, the Fundamental Change Repurchase Notice must comply with applicable
Depositary procedures. 
 Notwithstanding anything herein to the contrary, any Holder delivering to the Paying Agent the Fundamental Change
Repurchase Notice contemplated by this Section 15.02 shall have the right to withdraw, in whole or in part, such Fundamental Change Repurchase Notice at 

  
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any time prior to the close of business on the Business Day immediately preceding the Fundamental Change Repurchase Date by delivery of a written notice of withdrawal to the Paying Agent in
accordance with Section 15.03. 
 The Paying Agent shall promptly notify the Company of the receipt by it of any Fundamental Change
Repurchase Notice or written notice of withdrawal thereof. 
 (c) On or before the 20th calendar day after the occurrence of the effective
date of a Fundamental Change, the Company shall provide to all Holders of Notes and the Trustee and the Paying Agent (in the case of a Paying Agent other than the Trustee) a notice (the “Fundamental Change Company Notice”) of the
occurrence of the effective date of the Fundamental Change and of the repurchase right at the option of the Holders arising as a result thereof. In the case of Physical Notes, such notice shall be by first class mail or, in the case of Global Notes,
such notice shall be delivered in accordance with the applicable procedures of the Depositary. Each Fundamental Change Company Notice shall specify: 

(i) the events causing the Fundamental Change; 

(ii) the date of the Fundamental Change; 

(iii) the last date on which a Holder may exercise the repurchase right pursuant to this Article 15; 

(iv) the Fundamental Change Repurchase Price; 

(v) the Fundamental Change Repurchase Date; 

(vi) the name and address of the Paying Agent and the Conversion Agent, if applicable; 

(vii) if applicable, the Conversion Rate and any adjustments to the Conversion Rate; 

(viii) that the Notes with respect to which a Fundamental Change Repurchase Notice has been delivered by a Holder may be
converted only if the Holder withdraws the Fundamental Change Repurchase Notice in accordance with the terms of this Indenture; and 

(ix) the procedures that Holders must follow to require the Company to repurchase their Notes. 

No failure of the Company to give the foregoing notices and no defect therein shall limit the Holders’ repurchase rights or affect the
validity of the proceedings for the repurchase of the Notes pursuant to this Section 15.02. 
 At the Company’s request given at
least five (5) Business Days prior to the date such notice is required to be sent to Holders (or such shorter time as agreed by the Trustee), the Trustee shall give such notice in the Company’s name and at the Company’s expense;
provided, however, that, in all cases, the text of such Fundamental Change Company Notice shall be prepared by the Company. 

  
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 (d) Notwithstanding the foregoing, no Notes may be repurchased by the Company on any date at the
option of the Holders upon a Fundamental Change if the principal amount of the Notes has been accelerated, and such acceleration has not been rescinded, on or prior to such date (except in the case of an acceleration resulting from a Default by the
Company in the payment of the Fundamental Change Repurchase Price with respect to such Notes). The Paying Agent will promptly return to the respective Holders thereof any Physical Notes held by it during the acceleration of the Notes (except in the
case of an acceleration resulting from a Default by the Company in the payment of the Fundamental Change Repurchase Price with respect to such Notes), or any instructions for book-entry transfer of the Notes
in compliance with the procedures of the Depositary shall be deemed to have been cancelled, and, upon such return or cancellation, as the case may be, the Fundamental Change Repurchase Notice with respect thereto shall be deemed to have been
withdrawn. 
 Section 15.03. Withdrawal of Fundamental Change Repurchase Notice. (a) A Fundamental Change Repurchase Notice
may be withdrawn (in whole or in part) by means of a written notice of withdrawal delivered to the Corporate Trust Office of the Paying Agent in accordance with this Section 15.03 at any time prior to the close of business on the Business Day
immediately preceding the Fundamental Change Repurchase Date, specifying: 
 (i) the principal amount of the Notes with
respect to which such notice of withdrawal is being submitted, which must be $1,000 or an integral multiple thereof, 
 (ii)
if Physical Notes have been issued, the certificate number of the Note in respect of which such notice of withdrawal is being submitted, and 

(iii) the principal amount, if any, of such Note that remains subject to the original Fundamental Change Repurchase Notice,
which portion must be in principal amounts of $1,000 or an integral multiple of $1,000; 
 provided, however, that if the Notes are Global
Notes, the notice must comply with applicable procedures of the Depositary. 
 Section 15.04. Deposit of Fundamental Change
Repurchase Price. (a) The Company will deposit with the Trustee (or other Paying Agent appointed by the Company, or if the Company is acting as its own Paying Agent, set aside, segregate and hold in trust as provided in Section 4.04)
on or prior to 11:00 a.m., New York City time, on the Fundamental Change Repurchase Date an amount of money sufficient to repurchase all of the Notes to be repurchased at the appropriate Fundamental Change Repurchase Price. Subject to receipt of
funds and/or Notes by the Trustee (or other Paying Agent appointed by the Company), payment for Notes surrendered for repurchase (and not withdrawn prior to the close of business on the Business Day immediately preceding the Fundamental Change
Repurchase Date) will be made on the later of (i) the Fundamental Change Repurchase Date (provided the Holder has satisfied the conditions in Section 15.02) and (ii) the time of book-entry transfer or the delivery of such Note
to the Trustee (or other Paying Agent appointed by the Company) by the Holder thereof in the manner required 

  
 88 

 
by Section 15.02 by mailing checks for the amount payable to the Holders of such Notes entitled thereto as they shall appear in the Note Register; provided, however, that
payments to the Depositary shall be made by wire transfer of immediately available funds to the account of the Depositary or its nominee. The Trustee shall, promptly after such payment and upon written demand by the Company, return to the Company
any funds in excess of the Fundamental Change Repurchase Price. 
 (b) If by 11:00 a.m. New York City time, on the Fundamental Change
Repurchase Date, the Trustee (or other Paying Agent appointed by the Company) holds money sufficient to make payment on all the Notes or portions thereof that are to be repurchased on such Fundamental Change Repurchase Date, then, with respect to
the Notes that have been properly surrendered for repurchase and have not been validly withdrawn, (i) such Notes will cease to be outstanding, (ii) interest will cease to accrue on such Notes (whether or not book-entry transfer of the
Notes has been made or the Notes have been delivered to the Trustee or Paying Agent) and (iii) all other rights of the Holders of such Notes will terminate (other than the right to receive the Fundamental Change Repurchase Price and, if applicable,
accrued and unpaid interest). 
 (c) Upon surrender of a Note that is to be repurchased in part pursuant to Section 15.02, the Company
shall execute and the Trustee shall authenticate and deliver to the Holder a new Note in an authorized denomination equal in principal amount to the unrepurchased portion of the Note surrendered. 

Section 15.05. Covenant to Comply with Applicable Laws Upon Repurchase of Notes. In connection with any repurchase offer pursuant
to a Fundamental Change Repurchase Notice, the Company will, if required: 
 (a) comply with the provisions of the tender offer rules under
the Exchange Act; 
 (b) file a Schedule TO or any other required schedule under the Exchange Act; and 

(c) otherwise comply in all material respects with all federal and state securities laws in connection with any offer by the Company to
repurchase the Notes; 
 in each case, so as to permit the rights and obligations under this Article 15 to be exercised in the time and in the manner
specified in this Article 15. 
 ARTICLE 16 

NO REDEMPTION 

Section 16.01. No Redemption. The Notes shall not be redeemable by the Company prior to the Maturity Date, and no sinking fund is
provided for the Notes. 

  
 89 

 ARTICLE 17 

MISCELLANEOUS PROVISIONS 

Section 17.01. Provisions Binding on Company’s Successors. All the covenants, stipulations, promises and
agreements of the Company contained in this Indenture shall bind its successors and assigns whether so expressed or not. 

Section 17.02. Official Acts by Successor Corporation. Any act or proceeding by any provision of this Indenture authorized or
required to be done or performed by any board, committee or Officer of the Company shall and may be done and performed with like force and effect by the like board, committee or officer of any corporation or other entity that shall at the time be
the lawful sole successor of the Company. 
 Section 17.03. Addresses for Notices, Etc. Any notice or demand that by any
provision of this Indenture is required or permitted to be given or served by the Trustee or by the Holders on the Company shall be deemed to have been sufficiently given or made, for all purposes if given or served by being deposited postage
prepaid by registered or certified mail in a post office letter box addressed (until another address is filed by the Company with the Trustee) to NantHealth, Inc., 9922 Jefferson Blvd., Culver City, CA 90232, Attention: General Counsel. Any notice,
direction, request or demand hereunder to or upon the Trustee shall be deemed to have been sufficiently given or made, for all purposes, if given or served by being deposited postage prepaid by registered or certified mail in a post office letter
box addressed to the Corporate Trust Office or sent electronically in PDF format, whether sent by mail or electronically, upon actual receipt by the Trustee. 

The Trustee, by notice to the Company, may designate additional or different addresses for subsequent notices or communications. 

Any notice or communication given to a Holder shall be sent electronically through the facilities of the Depositary (in the case of Holders of
Global Notes) or mailed to it by first class mail, postage prepaid, at its address as it appears on the Note Register and shall be sufficiently given to it if so mailed within the time prescribed. 

Failure to give a notice or communication to a Holder or any defect in it shall not affect its sufficiency with respect to other Holders. If a
notice or communication is given in the manner provided above, it is duly given, whether or not the addressee receives it. 
 In case by
reason of the suspension of regular mail service or by reason of any other cause it shall be impracticable to give such notice to Holders by mail, then such notification as shall be made with the approval of the Trustee shall constitute a sufficient
notification for every purpose hereunder. 
 Section 17.04. Governing Law; Jurisdiction. THIS INDENTURE AND EACH NOTE, AND ANY
CLAIM, CONTROVERSY OR DISPUTE ARISING UNDER OR RELATED TO THIS INDENTURE AND EACH NOTE, SHALL BE GOVERNED BY, AND CONSTRUED IN ACCORDANCE WITH, THE LAWS OF THE STATE OF NEW YORK (WITHOUT REGARD TO THE CONFLICTS OF LAWS PROVISIONS THEREOF). 

  
 90 

 The Company irrevocably consents and agrees, for the benefit of the Holders from time to time of
the Notes and the Trustee, that any legal action, suit or proceeding against it with respect to obligations, liabilities or any other matter arising out of or in connection with this Indenture or the Notes may be brought in the courts of the State
of New York or the courts of the United States located in the Borough of Manhattan, New York City, New York and, until amounts due and to become due in respect of the Notes have been paid, hereby irrevocably consents and submits to the non-exclusive jurisdiction of each such court in personam, generally and unconditionally with respect to any action, suit or proceeding for itself in respect of its properties, assets and revenues. 

The Company irrevocably and unconditionally waives, to the fullest extent permitted by law, any objection which it may now or hereafter have
to the laying of venue of any of the aforesaid actions, suits or proceedings arising out of or in connection with this Indenture brought in the courts of the State of New York or the courts of the United States located in the Borough of Manhattan,
New York City, New York and hereby further irrevocably and unconditionally waives and agrees not to plead or claim in any such court that any such action, suit or proceeding brought in any such court has been brought in an inconvenient forum. 

Section 17.05. Evidence of Compliance with Conditions Precedent; Certificates and Opinions of Counsel to Trustee. Upon any
application or demand by the Company to the Trustee to take any action under any of the provisions of this Indenture, the Company shall, if requested by the Trustee, furnish to the Trustee an Officer’s Certificate and an Opinion of Counsel
stating that such action is permitted by the terms of this Indenture. 
 Each Officer’s Certificate or Opinion of Counsel, as the case
may be, provided for, by or on behalf of the Company in this Indenture and delivered to the Trustee with respect to compliance with this Indenture (other than the Officer’s Certificates provided for in Section 4.08) shall include
(a) a statement that the person signing such certificate is familiar with the requested action and this Indenture; (b) a brief statement as to the nature and scope of the examination or investigation upon which the statement contained in
such certificate is based; (c) a statement that, in the judgment of such person, he or she has made such examination or investigation as is necessary to enable him or her to express an informed judgment as to whether or not such action is
permitted by this Indenture; and (d) a statement as to whether or not, in the judgment of such person, such action is permitted by this Indenture and that all conditions precedent thereto have been complied with. 

Notwithstanding anything to the contrary in this Section 17.05, if any provision in this Indenture specifically provides that the Trustee
shall or may receive an Opinion of Counsel in connection with any action to be taken by the Trustee or the Company hereunder, the Trustee shall be entitled to such Opinion of Counsel. 

Section 17.06. Legal Holidays. In any case where any Interest Payment Date, Fundamental Change Repurchase Date or Maturity Date is
not a Business Day, then any action to be taken on such date need not be taken on such date, but may be taken on the next succeeding Business Day with the same force and effect as if taken on such date, and no interest shall accrue in respect of the
delay. 

  
 91 

 Section 17.07. No Security Interest Created. Nothing in this Indenture or in the
Notes, expressed or implied, shall be construed to constitute a security interest under the Uniform Commercial Code or similar legislation, as now or hereafter enacted and in effect, in any jurisdiction. 

Section 17.08. Benefits of Indenture. Nothing in this Indenture or in the Notes, expressed or implied, shall give to any Person,
other than the Holders, the parties hereto, any Paying Agent, any Conversion Agent, any authenticating agent, any Note Registrar and their successors hereunder, any benefit or any legal or equitable right, remedy or claim under this Indenture. 

Section 17.09. Table of Contents, Headings, Etc. The table of contents and the titles and headings of the articles and sections of
this Indenture have been inserted for convenience of reference only, are not to be considered a part hereof, and shall in no way modify or restrict any of the terms or provisions hereof. 

Section 17.10. Authenticating Agent. The Trustee may appoint an authenticating agent that shall be authorized to act on its behalf
and subject to its direction in the authentication and delivery of Notes in connection with the original issuance thereof and transfers and exchanges of Notes hereunder, including under Section 2.04, Section 2.05, Section 2.06,
Section 2.07, Section 10.04 and Section 15.04 as fully to all intents and purposes as though the authenticating agent had been expressly authorized by this Indenture and those Sections to authenticate and deliver Notes. For all
purposes of this Indenture, the authentication and delivery of Notes by the authenticating agent shall be deemed to be authentication and delivery of such Notes “by the Trustee” and a certificate of authentication executed on behalf of the
Trustee by an authenticating agent shall be deemed to satisfy any requirement hereunder or in the Notes for the Trustee’s certificate of authentication. Such authenticating agent shall at all times be a Person eligible to serve as trustee
hereunder pursuant to Section 7.08. 
 Any corporation or other entity into which any authenticating agent may be merged or converted
or with which it may be consolidated, or any corporation or other entity resulting from any merger, consolidation or conversion to which any authenticating agent shall be a party, or any corporation or other entity succeeding to the corporate trust
business of any authenticating agent, shall be the successor of the authenticating agent hereunder, if such successor corporation or other entity is otherwise eligible under this Section 17.10, without the execution or filing of any paper or
any further act on the part of the parties hereto or the authenticating agent or such successor corporation or other entity. 
 Any
authenticating agent may at any time resign by giving written notice of resignation to the Trustee and to the Company. The Trustee may at any time terminate the agency of any authenticating agent by giving written notice of termination to such
authenticating agent and to the Company. Upon receiving such a notice of resignation or upon such a termination, or in case at any time any authenticating agent shall cease to be eligible under this Section, the Trustee may appoint a successor
authenticating agent (which may be the Trustee), shall give written notice of such appointment to the Company and shall give notice of such appointment to all Holders as the names and addresses of such Holders appear on the Note Register. 

  
 92 

 The Company agrees to pay to the authenticating agent from time to time reasonable compensation
for its services although the Company may terminate the authenticating agent, if it determines such agent’s fees to be unreasonable. 

The provisions of Section 7.02, Section 7.03, Section 7.04, Section 8.03 and this Section 17.10 shall be applicable
to any authenticating agent. 
 If an authenticating agent is appointed pursuant to this Section 17.10, the Notes may have endorsed
thereon, in addition to the Trustee’s certificate of authentication, an alternative certificate of authentication in the following form: 
  

	
	                                      
                                         
     ,
	 as Authenticating Agent, certifies that this is one of the Notes described

in the within-named Indenture.

 

			
	By:	 	  

	Authorized Signatory

 Section 17.11. Execution in Counterparts. This Indenture may be executed in any number of
counterparts, each of which shall be an original, but such counterparts shall together constitute but one and the same instrument. The exchange of copies of this Indenture and of signature pages by facsimile or PDF transmission shall constitute
effective execution and delivery of this Indenture as to the parties hereto and may be used in lieu of the original Indenture for all purposes. Signatures of the parties hereto transmitted by facsimile or PDF shall be deemed to be their original
signatures for all purposes. 
 Section 17.12. Severability. In the event any provision of this Indenture or in the Notes shall
be invalid, illegal or unenforceable, then (to the extent permitted by law) the validity, legality or enforceability of the remaining provisions shall not in any way be affected or impaired. 

Section 17.13. Waiver of Jury Trial. EACH OF THE COMPANY AND THE TRUSTEE HEREBY IRREVOCABLY WAIVES, TO THE FULLEST EXTENT
PERMITTED BY APPLICABLE LAW, ANY AND ALL RIGHT TO TRIAL BY JURY IN ANY LEGAL PROCEEDING ARISING OUT OF OR RELATING TO THIS INDENTURE, THE NOTES OR THE TRANSACTIONS CONTEMPLATED HEREBY. 

Section 17.14. Force Majeure. In no event shall the Trustee be responsible or liable for any failure or delay in the performance
of its obligations hereunder arising out of or caused by, directly or indirectly, forces beyond its control, including, without limitation, strikes, work stoppages, accidents, acts of war or terrorism, civil or military disturbances, nuclear or
natural catastrophes or acts of God, and interruptions, loss or malfunctions of utilities, communications or computer (software and hardware) services; it being understood that the Trustee shall use reasonable efforts that are consistent with
accepted practices in the banking industry to resume performance as soon as practicable under the circumstances. 

  
 93 

 Section 17.15. Calculations. The Company shall be responsible for making all
calculations called for under this Indenture and the Notes. These calculations include, but are not limited to, determinations of the Trading Price of the Notes, determinations of whether the Notes are convertible and determinations of the Last
Reported Sale Prices of the Common Stock, the Daily VWAPs, the Daily Conversion Values, the Daily Settlement Amounts, Interest Make-Whole Payment, accrued interest payable on the Notes, any Additional Interest payable on the Notes and the Conversion
Rate of the Notes. The Company shall make all these calculations in good faith and, absent manifest error, the Company’s calculations shall be final and binding on Holders of Notes, the Trustee and the Conversion Agent (if other than the
Trustee). The Company shall provide a schedule of its calculations to each of the Trustee and the Conversion Agent, and each of the Trustee and Conversion Agent is entitled to rely conclusively upon the accuracy of the Company’s calculations
without independent verification. The Trustee will forward the Company’s calculations to any Holder of Notes upon the written request of that Holder at the sole cost and expense of the Company. The Trustee (including in its capacities as Note
Registrar, Paying Agent, Bid Solicitation Agent and Conversion Agent, as the case may be) shall have no responsibility to determine the Trading Price of the Notes or whether the Notes are convertible pursuant to Article 14. 

Section 17.16. USA PATRIOT Act. The parties hereto acknowledge that in accordance with Section 326 of the USA PATRIOT Act,
the Trustee, like all financial institutions and in order to help fight the funding of terrorism and money laundering, is required to obtain, verify, and record information that identifies each person or legal entity that establishes a relationship
or opens an account with the Trustee. The parties to this Indenture agree that they will provide the Trustee with such information as it may request in order for the Trustee to satisfy the requirements of the USA PATRIOT Act. 

[Remainder of page intentionally left blank] 

  
 94 

 IN WITNESS WHEREOF, the parties hereto have caused this Indenture to be duly executed as of the
date first written above. 
  

					
	NANTHEALTH, INC.
		
	By:	 	 /s/ Charles Kim

		 	Name:	 	Charles Kim
		 	Title:	 	General Counsel and Secretary
	
	U.S. BANK NATIONAL ASSOCIATION, as Trustee
		
	By:	 	 /s/ Paula Oswald

		 	Name:	 	Paula Oswald
		 	Title:	 	Vice President

 EXHIBIT A 

[FORM OF FACE OF NOTE] 
 [INCLUDE
FOLLOWING LEGEND IF A GLOBAL NOTE] 
 [UNLESS THIS CERTIFICATE IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY,
A NEW YORK CORPORATION (“DTC”), TO THE COMPANY OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE, OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER NAME AS IS REQUESTED BY AN
AUTHORIZED REPRESENTATIVE OF DTC (AND ANY PAYMENT HEREUNDER IS MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC), ANY TRANSFER, PLEDGE, OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY
PERSON IS WRONGFUL INASMUCH AS THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN.] 
 [INCLUDE FOLLOWING LEGEND IF A
RESTRICTED SECURITY (OTHER THAN AN AFFILIATE NOTE)] 
 [THIS SECURITY AND THE COMMON STOCK, IF ANY, ISSUABLE UPON CONVERSION OF THIS
SECURITY HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND MAY NOT BE OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED EXCEPT IN ACCORDANCE WITH THE FOLLOWING SENTENCE. BY ITS ACQUISITION
HEREOF OR OF A BENEFICIAL INTEREST HEREIN, THE ACQUIRER: 
 AGREES FOR THE BENEFIT OF NANTHEALTH, INC. (THE “COMPANY”) THAT IT
WILL NOT OFFER, SELL, PLEDGE OR OTHERWISE TRANSFER THIS SECURITY OR ANY BENEFICIAL INTEREST HEREIN PRIOR TO THE DATE THAT IS THE LATER OF (X) ONE YEAR AFTER THE LAST ORIGINAL ISSUE DATE HEREOF OR SUCH SHORTER PERIOD OF TIME AS PERMITTED BY RULE
144 UNDER THE SECURITIES ACT OR ANY SUCCESSOR PROVISION THEREUNDER AND (Y) SUCH LATER DATE, IF ANY, AS MAY BE REQUIRED BY APPLICABLE LAW, EXCEPT: 

(A) TO THE COMPANY OR ANY SUBSIDIARY THEREOF, OR 

(B) PURSUANT TO A REGISTRATION STATEMENT WHICH HAS BECOME EFFECTIVE UNDER THE SECURITIES ACT, OR 

(C) WITHIN THE UNITED STATES, TO A QUALIFIED INSTITUTIONAL BUYER IN COMPLIANCE WITH RULE 144A UNDER THE SECURITIES ACT, OR 

  
 A-1 

 (D) OUTSIDE THE UNITED STATES, THROUGH OFFERS AND SALES THAT OCCUR OUTSIDE THE
UNITED STATES WITHIN THE MEANING OF REGULATION S UNDER THE SECURITIES ACT, OR 
 (E) PURSUANT TO AN EXEMPTION FROM
REGISTRATION PROVIDED BY RULE 144 UNDER THE SECURITIES ACT OR ANY OTHER AVAILABLE EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT. 

PRIOR TO THE REGISTRATION OF ANY TRANSFER IN ACCORDANCE WITH CLAUSE (E) ABOVE, THE COMPANY AND THE TRUSTEE RESERVE THE RIGHT TO REQUIRE
THE DELIVERY OF SUCH LEGAL OPINIONS, CERTIFICATIONS OR OTHER EVIDENCE AS MAY REASONABLY BE REQUIRED IN ORDER TO DETERMINE THAT THE PROPOSED TRANSFER IS BEING MADE IN COMPLIANCE WITH THE SECURITIES ACT AND APPLICABLE STATE SECURITIES LAWS. NO
REPRESENTATION IS MADE AS TO THE AVAILABILITY OF ANY EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT.] 
 [INCLUDE
FOLLOWING LEGEND IF SECURITY IS AN AFFILIATE NOTE] 
 [THIS SECURITY AND THE COMMON STOCK, IF ANY, ISSUABLE UPON CONVERSION OF THIS SECURITY
HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND MAY NOT BE OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED EXCEPT IN ACCORDANCE WITH THE FOLLOWING SENTENCE. BY ITS ACQUISITION HEREOF
OR OF A BENEFICIAL INTEREST HEREIN, THE ACQUIRER: 
 AGREES FOR THE BENEFIT OF NANTHEALTH, INC. (THE “COMPANY”) THAT IT
WILL NOT OFFER, SELL, PLEDGE OR OTHERWISE TRANSFER THIS SECURITY OR ANY BENEFICIAL INTEREST HEREIN PRIOR TO THE DATE THAT IS THE LATER OF (X) ONE YEAR AFTER THE LAST ORIGINAL ISSUE DATE HEREOF OR SUCH SHORTER PERIOD OF TIME AS PERMITTED BY RULE
144 UNDER THE SECURITIES ACT OR ANY SUCCESSOR PROVISION THEREUNDER AND (Y) SUCH LATER DATE, IF ANY, AS MAY BE REQUIRED BY APPLICABLE LAW, EXCEPT: 

(A) TO THE COMPANY OR ANY SUBSIDIARY THEREOF, OR 

(B) PURSUANT TO A REGISTRATION STATEMENT WHICH HAS BECOME EFFECTIVE UNDER THE SECURITIES ACT, OR 

(C) WITHIN THE UNITED STATES, TO A QUALIFIED INSTITUTIONAL BUYER IN COMPLIANCE WITH RULE 144A UNDER THE SECURITIES ACT, OR 

(D) OUTSIDE THE UNITED STATES, THROUGH OFFERS AND SALES THAT OCCUR OUTSIDE THE UNITED STATES WITHIN THE MEANING OF REGULATION S
UNDER THE SECURITIES ACT, OR 
 (E) PURSUANT TO AN EXEMPTION FROM REGISTRATION PROVIDED BY RULE 144 UNDER THE SECURITIES ACT
OR ANY OTHER AVAILABLE EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT. 

  
 A-2 

 PRIOR TO THE REGISTRATION OF ANY TRANSFER IN ACCORDANCE WITH CLAUSE (E) ABOVE, THE COMPANY
AND THE TRUSTEE RESERVE THE RIGHT TO REQUIRE THE DELIVERY OF SUCH LEGAL OPINIONS, CERTIFICATIONS OR OTHER EVIDENCE AS MAY REASONABLY BE REQUIRED IN ORDER TO DETERMINE THAT THE PROPOSED TRANSFER IS BEING MADE IN COMPLIANCE WITH THE SECURITIES ACT AND
APPLICABLE STATE SECURITIES LAWS. NO REPRESENTATION IS MADE AS TO THE AVAILABILITY OF ANY EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT. 

NO AFFILIATE (AS DEFINED IN RULE 144 UNDER THE SECURITIES ACT) OF THE COMPANY OR PERSON THAT HAS BEEN AN AFFILIATE (AS DEFINED IN RULE 144
UNDER THE SECURITIES ACT) OF THE COMPANY DURING THE THREE IMMEDIATELY PRECEDING MONTHS MAY OFFER, SELL, PLEDGE OR OTHERWISE TRANSFER THIS SECURITY OR A BENEFICIAL INTEREST HEREIN UNLESS PURSUANT TO A REGISTRATION STATEMENT WHICH HAS BECOME EFFECTIVE
UNDER THE SECURITIES ACT OR PURSUANT TO AN EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT IN A TRANSACTION THAT RESULTS IN SUCH SECURITY OR COMMON STOCK, AS THE CASE MAY BE, NO LONGER BEING A “RESTRICTED SECURITY” (AS
DEFINED IN RULE 144 UNDER THE SECURITIES ACT).] 

  
 A-3 

 NANTHEALTH, INC. 

5.50% Convertible Senior Note due 2021 
  

			
	No. [            ]	  	[Initially]1 $[        ]

 CUSIP No. [            ] 

NantHealth, Inc., a corporation duly organized and validly existing under the laws of the State of Delaware (the “Company,”
which term includes any successor corporation or other entity under the Indenture referred to on the reverse hereof), for value received hereby promises to pay to [CEDE & CO.]2
[            ]3, or registered assigns, the principal sum [as set forth in the “Schedule of Exchanges of Notes” attached
hereto]4 [of $[        ]]5, which amount, taken together with the principal amounts of all other
outstanding Notes, shall not, unless permitted by the Indenture, exceed $100,000,000 in aggregate at any time (or $115,000,000 if the Initial Purchasers exercise their option to purchase additional Notes in full as set forth in the Purchase
Agreement), in accordance with the rules and procedures of the Depositary, on December 15, 2021, and interest thereon as set forth below. 

This Note shall bear interest at the rate of 5.50% per year from December 21, 2016, or from the most recent date to which interest had
been paid or provided for to, but excluding, the next scheduled Interest Payment Date until December 15, 2021. Interest is payable semi-annually in arrears on each June 15 and December 15, commencing on June 15, 2017, to Holders
of record at the close of business on the preceding June 1 and December 1 (whether or not such day is a Business Day), respectively. Accrued interest on this Note shall be computed on the basis of a
360-day year composed of twelve 30-day months and, for partial months, on the basis of the number of days actually elapsed in a
30-day month. Additional Interest will be payable as set forth in Section 4.06(d), Section 4.06(e) and Section 6.03 of the within-mentioned Indenture, and any reference to interest on, or in respect of,
any Note therein shall be deemed to include Additional Interest if, in such context, Additional Interest is, was or would be payable pursuant to any of such Section 4.06(d), Section 4.06(e) or Section 6.03, and any express mention of the
payment of Additional Interest in any provision therein shall not be construed as excluding Additional Interest in those provisions thereof where such express mention is not made. 

Any Defaulted Amounts shall accrue interest per annum at the rate borne by the Notes, subject to the enforceability thereof under applicable
law, from, and including, the relevant payment date to, but excluding, the date on which such Defaulted Amounts shall have been paid by the Company, at its election, in accordance with Section 2.03(c) of the Indenture. 

The Company shall pay the principal of and interest on this Note, if and so long as such Note is a Global Note, in immediately available funds
to the Depositary or its nominee, as the 
  

	1 	Include if a global note. 

	2 	Include if a global note. 

	3 	Include if a physical note. 

	4 	Include if a global note. 

	5 	 Include if a physical note. 

  
 A-4 

 
case may be, as the registered Holder of such Note. As provided in and subject to the provisions of the Indenture, the Company shall pay the principal of any Notes (other than Notes that are
Global Notes) at the office or agency designated by the Company for that purpose. The Company has initially designated the Trustee as its Paying Agent and Note Registrar in respect of the Notes and its agency in the United States of America as a
place where Notes may be presented for payment or for registration of transfer and exchange. 
 Reference is made to the further provisions
of this Note set forth on the reverse hereof, including, without limitation, provisions giving the Holder of this Note the right to convert this Note into cash, shares of Common Stock or a combination of cash and shares of Common Stock, as
applicable, on the terms and subject to the limitations set forth in the Indenture. Such further provisions shall for all purposes have the same effect as though fully set forth at this place. 

This Note, and any claim, controversy or dispute arising under or related to this Note, shall be construed in accordance with and governed
by the laws of the State of New York (without regard to the conflicts of laws provisions thereof). 
 In the case of any conflict
between this Note and the Indenture, the provisions of the Indenture shall control and govern. 
 This Note shall not be valid or become
obligatory for any purpose until the certificate of authentication hereon shall have been signed manually by the Trustee or a duly authorized authenticating agent under the Indenture. 

[Remainder of page intentionally left blank] 

  
 A-5 

 IN WITNESS WHEREOF, the Company has caused this Note to be duly executed. 

 

			
	NANTHEALTH, INC.
		
	By:	 	  

		 	Name:
		 	Title:

  

	
	 Dated:

	
	 TRUSTEE’S CERTIFICATE OF AUTHENTICATION

	
	 U.S. BANK NATIONAL ASSOCIATION

as Trustee, certifies that this is one of the Notes described

in the within-named Indenture.

 

			
	By:	 	  

		 	Authorized Signatory

  
 A-6 

 [FORM OF REVERSE OF NOTE] 

NANTHEALTH, INC. 
 5.50%
Convertible Senior Note due 2021 
 This Note is one of a duly authorized issue of Notes of the Company, designated as its 5.50% Convertible
Senior Notes due 2021 (the “Notes”), initially limited to the aggregate principal amount of $100,000,000 (as increased by an amount equal to the aggregate principal amount of any additional Notes purchased by the Initial Purchasers
pursuant to the exercise of their option to purchase additional Notes as set forth in the Purchase Agreement) all issued or to be issued under and pursuant to an Indenture dated as of December 21, 2016 (the “Indenture”),
between the Company and U.S. Bank National Association (the “Trustee”), to which Indenture and all indentures supplemental thereto reference is hereby made for a description of the rights, limitations of rights, obligations, duties
and immunities thereunder of the Trustee, the Company and the Holders of the Notes. Additional Notes may be issued in an unlimited aggregate principal amount, subject to certain conditions specified in the Indenture. Capitalized terms used in this
Note and not defined in this Note shall have the respective meanings set forth in the Indenture. 
 In case certain Events of Default shall
have occurred and be continuing, the principal of, and interest on, all Notes may be declared, by either the Trustee or Holders of at least 25% in aggregate principal amount of Notes then outstanding, and upon said declaration shall become, due and
payable, in the manner, with the effect and subject to the conditions and certain exceptions set forth in the Indenture. 
 Subject to the
terms and conditions of the Indenture, the Company will make all payments and deliveries in respect of the Fundamental Change Repurchase Price on the Fundamental Change Repurchase Date and the principal amount on the Maturity Date, as the case may
be, to the Holder who surrenders a Note to a Paying Agent to collect such payments in respect of the Note. The Company will pay cash amounts in money of the United States that at the time of payment is legal tender for payment of public and private
debts. 
 The Indenture contains provisions permitting the Company and the Trustee in certain circumstances, without the consent of the
Holders of the Notes, and in certain other circumstances, with the consent of the Holders of not less than a majority in aggregate principal amount of the Notes at the time outstanding, evidenced as in the Indenture provided, to execute supplemental
indentures modifying the terms of the Indenture and the Notes as described therein. It is also provided in the Indenture that, subject to certain exceptions, the Holders of a majority in aggregate principal amount of the Notes at the time
outstanding may on behalf of the Holders of all of the Notes waive any past Default or Event of Default under the Indenture and its consequences. 

No reference herein to the Indenture and no provision of this Note or of the Indenture shall alter or impair the obligation of the Company,
which is absolute and unconditional, to pay or deliver, as the case may be, the principal (including the Fundamental Change Repurchase Price, if applicable) of, accrued and unpaid interest on, and the consideration due upon conversion of, this Note
at the place, at the respective times, at the rate and in the lawful money and/or shares of Common Stock, as the case may be, herein prescribed. 

  
 A-7 

 The Notes are issuable in registered form without coupons in denominations of $1,000 principal
amount and integral multiples thereof. At the office or agency of the Company referred to on the face hereof, and in the manner and subject to the limitations provided in the Indenture, Notes may be exchanged for a like aggregate principal amount of
Notes of other authorized denominations, without payment of any service charge but, if required by the Company or Trustee, with payment of a sum sufficient to cover any transfer or similar tax that may be imposed in connection therewith as a result
of the name of the Holder of the new Notes issued upon such exchange of Notes being different from the name of the Holder of the old Notes surrendered for such exchange. 

The Notes are not subject to redemption through the operation of any sinking fund or otherwise. 

Upon the occurrence of a Fundamental Change, the Holder has the right, at such Holder’s option, to require the Company to repurchase for
cash all of such Holder’s Notes or any portion thereof (in principal amounts of $1,000 or integral multiples thereof) on the Fundamental Change Repurchase Date at a price equal to the Fundamental Change Repurchase Price. 

Subject to the provisions of the Indenture, the Holder hereof has the right, at its option, during certain periods and upon the occurrence of
certain conditions specified in the Indenture, prior to the close of business on the Business Day immediately preceding the Maturity Date, to convert any Notes or portion thereof that is $1,000 or an integral multiple thereof, into cash, shares of
Common Stock or a combination of cash and shares of Common Stock, as applicable, at the Conversion Rate specified in the Indenture, as adjusted from time to time as provided in the Indenture. 

For any Conversion Date that occurs on or after the date that is one year after the last date of original issuance of the Notes, if the Last
Reported Sale Price of the Common Stock for at least 20 Trading Days (whether or not consecutive) during the period of 30 consecutive Trading Days ending within the five Trading Days immediately preceding a Conversion Date is greater than or equal
to 120% of the Conversion Price on each applicable Trading Day, the Company shall make an Interest Make-Whole Payment as provided in the Indenture. 

Terms used in this Note and defined in the Indenture are used herein as therein defined. 

  
 A-8 

 ABBREVIATIONS 

The following abbreviations, when used in the inscription of the face of this Note, shall be construed as though they were written out in full
according to applicable laws or regulations: 
 TEN COM = as tenants in common 

UNIF GIFT MIN ACT = Uniform Gifts to Minors Act 
 CUST =
Custodian 
 TEN ENT = as tenants by the entireties 
 JT TEN =
joint tenants with right of survivorship and not as tenants in common 
 Additional abbreviations may also be used though not in the above
list. 

  
 A-9 

 SCHEDULE A6 

SCHEDULE OF EXCHANGES OF NOTES 

NANTHEALTH, INC. 
 5.50%
Convertible Senior Notes due 2021 
 The initial principal amount of this Global Note is
             DOLLARS ($[        ]). The following increases or decreases in this Global Note have been made: 

 

																	
	 Date of exchange
	  	Amount of
decrease in
principal amount
of this Global Note	 	  	Amount of
increase in
principal amount
of this Global Note	 	  	Principal amount
of this Global Note
following such
decrease or
increase	 	  	Signature of
authorized
signatory of
Trustee or
Custodian	 
		  				  				  				  			
		  				  				  				  			
		  				  				  				  			
		  				  				  				  			
		  				  				  				  			
		  				  				  				  			
		  				  				  				  			
		  				  				  				  			
		  				  				  				  			
		  				  				  				  			
		  				  				  				  			
		  				  				  				  			
		  				  				  				  			
		  				  				  				  			
		  				  				  				  			
		  				  				  				  			
		  				  				  				  			
		  				  				  				  			
		  				  				  				  			
		  				  				  				  			
		  				  				  				  			
		  				  				  				  			

  

	6 	Include if a global note. 

  
 A-10 

 ATTACHMENT 1 

[FORM OF NOTICE OF CONVERSION] 

NANTHEALTH, INC. 
 5.50%
Convertible Senior Notes due 2021 
  

	To:	U.S. BANK NATIONAL ASSOCIATION 

 633 West Fifth Street, 24th Floor 

Los Angeles, California 90071 

Attention: P. Oswald (NantHealth, Inc. 5.50% Convertible Senior Notes due 2021) 

The undersigned registered owner of this Note hereby exercises the option to convert this Note, or the portion hereof (that is $1,000
principal amount or an integral multiple thereof) below designated, into cash, shares of Common Stock or a combination of cash and shares of Common Stock, as applicable, in accordance with the terms of the Indenture referred to in this Note, and
directs that any cash payable and any shares of Common Stock issuable and deliverable upon such conversion, together with any cash for any fractional share, and any Notes representing any unconverted principal amount hereof, be issued and delivered
to the registered Holder hereof unless a different name has been indicated below. If any shares of Common Stock or any portion of this Note not converted are to be issued in the name of a Person other than the undersigned, the undersigned will pay
all documentary, stamp or similar issue or transfer taxes, if any in accordance with Section 14.02(d) and Section 14.02(e) of the Indenture. Any amount required to be paid to the undersigned on account of interest accompanies this Note. Capitalized
terms used herein but not defined shall have the meanings ascribed to such terms in the Indenture. 
 The undersigned hereby represents and
warrants that the undersigned has full power and authority to execute this document and take all action in connection with this Note required hereby. 
  

									
	 Dated:
	 	  
	 		  	  
	 	
					
		 		 		  	  
	 	
		 		 		  	 Signature(s)
	 	
		 		 		  		 	

  

	
	  

	Signature Guarantee
	
	Signature(s) must be guaranteed by an eligible Guarantor Institution (banks, stock brokers, savings and loan associations and credit unions)

  
 1 

	
	with membership in an approved signature guarantee medallion program pursuant to Securities and Exchange Commission Rule 17Ad-15 if shares of Common Stock are to be issued, or Notes are to be
delivered, other than to and in the name of the registered holder.
	  
 Fill in for registration of shares if to be issued, and Notes if to be
delivered, other than to and in the name of the registered holder:

	
	  

	(Name)
	
	  

	(Street Address)
	
	  

	(City, State and Zip Code)
	Please print name and address

  

	
	 Principal amount to be converted (if less than all):

$        ,000

	
	NOTICE: The above signature(s) of the Holder(s) hereof must correspond with the name as written upon the face of the Note in every particular without alteration or enlargement or any change
whatever.

 
			
		
	  
	 	
	Social Security or Other Taxpayer	 	
	Identification Number	 	

  
 2 

 ATTACHMENT 2 

[FORM OF FUNDAMENTAL CHANGE REPURCHASE NOTICE] 

NANTHEALTH, INC. 
 5.50%
Convertible Senior Notes due 2021 
  

	To:	U.S. BANK NATIONAL ASSOCIATION 

 633 West Fifth Street, 24th Floor 

Los Angeles, California 90071 

Attention: P. Oswald (NantHealth, Inc. 5.50% Convertible Senior Notes due 2021) 

The undersigned registered owner of this Note hereby acknowledges receipt of a notice from NantHealth, Inc. (the “Company”)
as to the occurrence of a Fundamental Change with respect to the Company and specifying the Fundamental Change Repurchase Date and requests and instructs the Company to pay to the registered holder hereof in accordance with Section 15.02 of the
Indenture referred to in this Note (1) the entire principal amount of this Note, or the portion thereof (that is $1,000 principal amount or an integral multiple thereof) below designated, and (2) if such Fundamental Change Repurchase Date
does not fall during the period after a Regular Record Date and on or prior to the corresponding Interest Payment Date, accrued and unpaid interest, if any, thereon to, but excluding, such Fundamental Change Repurchase Date. Capitalized terms used
herein but not defined shall have the meanings ascribed to such terms in the Indenture. 
 The undersigned hereby represents and warrants
that the undersigned has full power and authority to execute this document and take all action in connection with this Note required hereby. 

In the case of Physical Notes, the certificate numbers of the Notes to be repurchased are as set forth below: 

 

			
	Dated:	 	  

 

	
	  

	Signature(s)
	
	  

	Social Security or Other Taxpayer
	Identification Number
	
	Principal amount to be repaid (if less than all): $        ,000
	
	NOTICE: The above signature(s) of the Holder(s) hereof must correspond with the name as written upon the face of the Note in every particular without alteration or enlargement or any change whatever.

  
 1 

 ATTACHMENT 3 

[FORM OF ASSIGNMENT AND TRANSFER] 

NANTHEALTH, INC. 
 5.50%
Convertible Senior Notes due 2021 
 For value received
                                         hereby
sell(s), assign(s) and transfer(s) unto                              (Please insert social security or
Taxpayer Identification Number of assignee) the within Note, and hereby irrevocably constitutes and appoints
                             attorney to transfer the said Note on the books of the Company, with full power
of substitution in the premises. 
 In connection with any transfer of the within Note occurring prior to the Resale Restriction Termination Date, as
defined in the Indenture governing such Note, the undersigned confirms that such Note is being transferred: 
 ☐ To NantHealth, Inc. or a subsidiary
thereof; or 
 ☐ Pursuant to a registration statement that has become or been declared effective under the Securities Act of 1933, as amended; or 

☐ Within the United States, pursuant to and in compliance with Rule 144A under the Securities Act of 1933, as amended; or 

☐ Outside the United States, through offers and sales that occur outside the United States within the meaning of Regulation S under the Securities Act
of 1933, as amended; or 
 ☐ Pursuant to and in compliance with Rule 144 under the Securities Act of 1933, as amended, or any other available
exemption from the registration requirements of the Securities Act of 1933, as amended. 
 The undersigned hereby represents and warrants that the
undersigned has full power and authority to execute this document and take all action in connection with this Note required hereby. 

  
 1 

			
	Dated:	 	  

	
	  

	
	  

	
	Signature(s)
	
	  

	Signature Guarantee
	
	Signature(s) must be guaranteed by an eligible Guarantor Institution (banks, stock brokers, savings and loan associations and credit unions) with membership in an approved signature guarantee medallion program pursuant to Securities
and Exchange Commission Rule 17Ad-15 if Notes are to be delivered, other than to and in the name of the registered holder.

NOTICE: The signature on the assignment must correspond with the name as written upon the face of the Note in every particular without alteration or
enlargement or any change whatever. 

  
 2

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