Document:

<PAGE>
                                                                   Exhibit 10.39

                              EMPLOYMENT AGREEMENT
                            (for Norman D. LaFrance)

         THIS EMPLOYMENT AGREEMENT (this "Agreement") is dated as of April 18,
2007 (the "Effective Date"), by and between Molecular Insight Pharmaceuticals,
Inc., a Massachusetts corporation having its principal place of business at 160
Second Street, Cambridge, Massachusetts 02142 (the "Employer"), and Norman D.
LaFrance (the "Employee").

                                   WITNESSETH:

         WHEREAS, the Employer is engaged in the business of developing and
marketing imaging pharmaceuticals which detect human disease; and

         WHEREAS, the Employee possesses the experience necessary in
administration and general and active supervision and direction of the daily
operations of a biopharmaceutical business in order to fulfill the
responsibilities as Senior Vice President, Clinical Development and Chief
Medical Officer of the Employer; and

         WHEREAS, the Employer desires to employ the Employee, and the Employee
desires to be employed by the Employer, all in accordance with the terms and
provisions of this Agreement.

         NOW, THEREFORE, in consideration of the covenants and promises
hereinafter contained, and for other good and valuable consideration, the
receipt and sufficiency of which are hereby acknowledged, the Employer and the
Employee represent, covenant and agree as follows:

         1.       Employment. The Employer hereby employs the Employee to serve
as Senior Vice President, Clinical Development and Chief Medical Officer in
accordance with the terms and provisions of this Agreement, and the Employee
hereby accepts such employment with the Employer.

         2.       Term. The term of this Agreement shall commence on the
Effective Date and shall continue until this Agreement is terminated as
hereinafter provided.

         3.       Compensation. As compensation for all services rendered by the
Employee to the Employer pursuant to this Agreement, the Employer shall pay to
the Employee the following amounts during the term of this Agreement:

                  (a)      Base Compensation. The Employer shall pay to the
Employee base compensation at no less than the rate set forth on Schedule A
attached hereto and herein incorporated by reference (the "Base Compensation").
The Base Compensation shall be payable pursuant to the Employer's standard
payroll practices, except as otherwise noted on Schedule A. The Base
Compensation shall be reviewed by the compensation committee of the Board of the
Employer annually and increases in the Base Compensation, if any, shall be
evidenced by the updating and initialing of Schedule A by both parties hereto.

<PAGE>

                  (b)      Incentive Bonus. In addition to the Base
Compensation, the Employee shall be eligible to receive an annual fiscal year
incentive bonus with a maximum annual amount equal to thirty percent (30%) of
the then current Base Compensation (the "Incentive Bonus"). Payment of the
Incentive Bonus shall be subject to the discretion of the Board and will be
based upon accomplishment of goals provided to the Employee by the President and
Chief Scientific Officer, and Chief Executive Officer ("CEO") from time to time
and based upon revenue growth, profitability and achievement of specific
corporate milestones. The Board may elect to award the Incentive Bonus to the
Employee in cash or in the Employer's capital stock (at its then-current fair
market value), but a capital stock bonus requires the consent of the Employee.

         4.       Vacation and Employee Benefits.

                  (a)      Vacation. The Employee shall be entitled to an annual
paid vacation equal to three (3) weeks annually. Vacation shall be taken at such
times so as not to interfere with the proper operation of the Employer's
business.

                  (b)      Benefits Generally. The Employee shall be entitled to
receive and participate in such employee benefits as the Employer shall from
time to time determine to provide to its executives generally.

                  (c)      Relocation Package. The Employee shall be entitled to
the relocation expenses as set forth on Schedule B attached hereto. Such
relocation expenses shall apply to the Employee's initial relocation only and
shall not apply to any subsequent moves. If, within one year of the Effective
Date, the Employee voluntarily resigns employment or if this Agreement is
terminated for "cause" by the Employer as set forth in Section 15(B) below, the
Employee shall reimburse the Employer for any and all relocation expenses paid
pursuant to this Section. The Employee acknowledges and agrees that any such
reimbursement amount owed to the Employer may be offset and deducted from any
wages and or other amounts that may be due and owing to the Employee at the
time.

         5.       Stock Incentives.

                  (a)      Options. Pursuant to the provisions of the Employer's
2006 Equity Incentive Plan, as may be amended from time to time (the "Plan"),
and subject to approval of the Employer's Board of Directors or its Compensation
Committee, the Employee will be granted an option to purchase 100,000 shares of
the Employer's Common Stock (the "Options") at an exercise price equal to the
fair market value per share on the date of grant (as determined by the
Employer's Board of Directors or its Compensation Committee pursuant to the
Plan), with such Options to be subject further to the terms and conditions of
the Plan and a separate option agreement.

                  (b)      Vesting. Of the Options, 75,000 will be subject to
the Employer's four (4) year vesting schedule with 25% vesting on each
anniversary of the Employee's date of hire ("Time Options") and 25,000 will be
subject to vesting on the satisfaction of certain performance milestones to be
set forth in the applicable separate option agreement. In the event of a Change

                                       2
<PAGE>

of Control (as defined below), all of the unvested Time Options shall vest
immediately prior to Change in Control, provided that the Employee is still
employed by the Employer on the date of such Change of Control, or is then
receiving a Severance Package.

                  (c)      Change of Control. Treatment of options on a Change
of Control (as defined in the Plan) will be as set forth in the applicable
separate option agreement.

         6.       Description of Duties. During the term of this Agreement, the
Employee shall be the Senior Vice President, Clinical Development and Chief
Medical Officer of the Employer and shall:

                  (a)      Devote on a full time basis all necessary time, best
efforts, professional skills, attention and energies to the fulfillment of the
duties customarily associated with such position and the accomplishment of the
goals provided by the President and Chief Scientific Officer, and CEO of the
Employer to the Employee from time to time; and

                  (b)      Act in accordance herewith, and in all accounts be
responsible and responsive to, the Board of Directors, the President and Chief
Scientific Officer, and CEO of Employer.

         7.       General Services. During the term of this Agreement, the
Employee shall:

                  (a)      Observe the Employer's policies and standards of
conduct, as well as customary standards of business conduct, including any
standards prescribed by law or regulation;

                  (b)      Perform his duties hereunder in a manner that
preserves and protects the Employer's business reputation; and

                  (c)      Do all things and render such services as may be
necessary or beneficial in carrying out any of the foregoing.

         8.       Non-Disclosure of Proprietary or Confidential Information and
Confidential Communications. For the purposes of this Section 8, the term
"Employer" shall include, and the protections granted the Employer hereunder
shall extend to any other entities now or hereinafter affiliated, acquired or
created by the Employer. The Employee recognizes and acknowledges that the
marketing plans and business strategy, the names and addresses of the Employer's
customers, the particular needs and application of such customers for diagnostic
imaging techniques, the names and addresses of the Employer's suppliers, the
Employer's purchasing history with its suppliers, the names and other pertinent
data concerning the persons employed by the Employer's suppliers who are
responsible for supplying the Employer with products and services, the
Employer's proprietary computer software programs, trade secrets and any other
confidential and proprietary information concerning the business or affairs of
the Employer (including but not limited to marketing and business plans and
strategies, research protocols, procedures data, results, and cost information)
(hereinafter collectively referred to as the Confidential Information)
constitute a valuable, proprietary, special and unique asset of the

                                       3
<PAGE>

Employer's business. The Employee further recognizes and acknowledges that any
communications, whether written, oral or otherwise, that the Employer or any of
the Employer's employees has with the Employer's existing or prospective
customers and clients and affiliated research institutions and scientists are
extremely confidential (hereinafter the "Confidential Communications"). The term
Confidential Information shall exclude any information that has been made public
through no fault of the Employee.

         The Employee shall not, for any reason whatsoever, during or after the
termination of his employment with the Employer, use, disclose or allow access
to, for his own benefit or for that of another, the Confidential Information or
the Confidential Communications (or any part thereof) to any person, firm,
corporation, association or other entity for any reason or for any purpose
whatsoever.

         In the event of a breach or threatened breach by the Employee of the
provisions of this Section, the Employer shall be entitled to an injunction
restraining the Employee from so using, disclosing or allowing access to, in
whole or in part, the Confidential Information and the Confidential
Communications or from rendering any services to any person, firm, corporation,
association or other entity to whom the Confidential Information or the
Confidential Communications, in whole or in part, have been disclosed or are
threatened to be disclosed. Nothing herein shall be construed as prohibiting the
Employer from pursuing any other remedies available to the Employer for such
breach or threatened breach, including, but not limited to, the recovery of
damages and reasonable attorneys' fees from the Employee.

         Upon termination of this Agreement by either party for any reason, the
Employee shall return to the Employer any of the Confidential Information,
Confidential Communications, charts, company literature, reports, Employer
credit cards or other proprietary materials of the Employer then in the
Employee's possession and all other materials of the Employer which the Board of
Directors of the Employer requests the Employee to so return.

         This Section shall in all respects survive any termination of this
Agreement and shall remain in full force and effect thereafter. In the event
that any provision of this Section 8 shall conflict with any term or condition
of any other confidentiality agreement between the Employer and the Employee,
then the more restrictive provision shall be deemed to apply in order to
accomplish the purposes of this Section 8 and such other agreements, that being
to protect the Employer's Confidential Information and Confidential
Communications.

         In the event of the Employee's breach of this Section 8, the Employee
shall immediately and irrevocably forfeit future payments under the Severance
Package as hereinafter defined in Section 15. Nothing in this paragraph shall be
construed to limit or cap the Employer's damages in the event of a breach of
this Section 8.

         9.       Covenant Not to Compete; Non-solicitation of Employees and
Customers. For the purposes of this Section 9, the term "Employer" shall
include, and the protections granted the Employer hereunder shall extend to any
other entities now or hereinafter affiliated, acquired or created by the
Employer. The Employee agrees that while employed by the Employer and for a
continuous period of one (1) year following the date of the termination of his
employment with

                                       4
<PAGE>

the Employer either voluntarily without "Good Reason" or involuntarily by the
Company for "cause" (the "Restricted Period"), he shall not (without the express
prior written consent of the Board of Directors of the Employer), directly or
indirectly, compete with the Employer. In construing the foregoing prohibition,
the Employee shall be deemed to be competing with the Employer if he shall
become self-employed in, or accept employment with, consult with, render
services to or become associated with, own, manage, operate, join, control, or
participate in the ownership, management, operation, or control of, or be
connected in any material manner with, or directly or indirectly enter into the
employment of, or make a substantial investment in, any corporation,
partnership, proprietorship or other type of business organization or entity
which engages in, any business (a "Competing Business") involving the sale,
distribution, development or research concerning diagnostic imaging of the human
cardio-vascular system or other lines of the Employer which directly and
materially competes with the product lines in or with which the Employer is then
currently involved.

         The Employee further agrees that, during his employment with the
Employer and during the Restricted Period, he shall not solicit any of the
Employer's employees, existing customers or prospective customers (of which the
Employee is then currently aware), affiliated research institutions or
scientists, on behalf of himself or any Competing Business.

         This Section 9 shall in all respects survive any termination of this
Agreement and shall remain in full force and effect during the Restricted
Period.

         In the event of the Employee's breach of this Section 9 during the
Restricted Period, the Employee shall immediately and irrevocably forfeit future
payments to the Employee under the Severance Package as hereinafter defined in
Section 15.

         10.      Assignment of Rights. Any and all information, data,
inventions, discoveries, materials, notebooks and other work product which the
Employee conceives, develops or acquires during his employment with the
Employer, which directly or indirectly relates to work performed for the
Employer, shall be the sole and exclusive property of the Employer. The Employee
shall promptly execute any and all documents necessary and take such further
actions as the Employer may deem necessary to assign any and all of the
Employee's right, title and interest in such property to the Employer.

         11.      Intellectual Property. For the purposes of this Section 11,
the term "Employer" shall include, and the protections granted the Employer
hereunder shall extend to any other entities now or hereinafter affiliated,
acquired or created by the Employer. During the Employee's employment at the
Employer, the Employee shall promptly assist with and execute any and all
applications, assignments or other documents which an officer or director of the
Employer shall deem necessary or useful in order to obtain and maintain patent,
trademark or other intellectual property protection for the Employer's products
or services. After the termination date of his employment with the Employer, the
Employee shall use reasonable efforts to assist the Employer on intellectual
property matters as they relate to his employment, and the Employer shall
reasonably compensate the Executive for his time and expense.

                                       5
<PAGE>

         12.      Documents, Records, etc. All documents, records, data,
apparatus, equipment and other physical property, whether or not pertaining to
Confidential Information, which are furnished to the Employee by the Employer or
are produced by the Employee in connection with the Employee's employment will
be and remain the sole property of the Employer. The Employee will return to the
Employer all such materials and property as and when requested by the Employer.
In any event, and whether or not the Employer so specifically requests, the
Employee will return all such materials and property immediately upon
termination of the Employee's employment for any reason. The Employee will not
retain any such material or property or any copies thereof after such
termination.

         13.      Third-Party Agreements and Rights. The Employee hereby
confirms that he is not bound by the terms of any agreement with any previous
employer or other party which restricts in any way the Employee's use or
disclosure of information or the Employee's engagement in any business. The
Employee represents to the Employer that the Employee's execution of this
Agreement, the Employee's employment with the Employer and the performance of
the Employee's proposed duties for the Employer will not violate any obligations
the Employee may have to any such previous employer or other party. In the
Employee's work for the Employer, the Employee will not disclose or make use of
any information in violation of any agreements with or rights of any such
previous employer or other party, and the Employee will not bring to the
premises of the Employer any copies or other tangible embodiments of nonpublic
information belonging to or obtained from any such previous employer or other
party.

         14.      Restricted Activities. During the term of this Agreement, the
Employee shall not engage in any business activities or ventures outside of the
business activities of the Employer without the express prior written consent of
the Employer's Board; provided, however, that nothing in this Agreement shall be
construed as preventing the Employee from:

                  (a)      investing the Employee's assets in any company or
other entity in a manner not prohibited by Section 9 and in such form or manner
as shall not require any material activities on the Employee's part in
connection with the operations or affairs of the companies or other entities in
which such investments are made; or

                  (b)      engaging in religious, charitable or other community
or non-profit activities that do not impair the Employee's ability to fulfill
the Employee's duties and responsibilities under this Agreement.

         15.      Termination.

                  A.       Termination Without Cause.

                           (a)     Notwithstanding anything herein to the
contrary, this Agreement may be terminated by either the Employer (by act of its
Board) or the Employee, at any time, without cause; provided, however, that the
party desirous of terminating this Agreement shall give the other party prior
written notice of such termination. In either event, the Employer may determine
the Employee's final day of employment hereunder. The date specified in any
notice

                                       6
<PAGE>

of termination as the Employee's final day of employment shall be referred to
herein as the Termination Date.

                           (b)     In the event that the Employer (by act of its
Board) terminates this Agreement without cause pursuant to this subsection (A)
of Section 15, or the Employee voluntarily resigns for Good Reason (defined
below), then the Employee shall be entitled to receive severance pay equal the
Base Compensation rate as of the Termination Date in equal monthly installments
for a period of twelve (12) months (the "Post-Termination Period") from the
Termination Date (the "Severance Package"). The Employer also agrees to make
available to the Employee, as part of the Severance Package, continuation of
group health plan benefits to the extent authorized by and consistent with 29
U.S.C. Section 1161 et seq. (commonly known as "COBRA"), and any other benefits
the Employee is receiving as of the Termination Date with the cost of the
regular premium for such benefits shared in the same relative proportion by the
Employer and the Employee as in effect on the Termination Date.

                           (c)     For purposes of this Agreement, "Good Reason"
shall mean:

                                   (i)      a reduction of the Employee's salary
or insurance benefits other than a reduction approved by the Employee in
writing; or

                                   (ii)     a significant change in the
Employee's title, responsibilities and/or duties which constitutes, when
compared to the Employee's title, responsibilities and/or duties as of the
Effective Date, a demotion; or

                                   (iii)    the relocation of the offices at
which the Employee is principally employed as of the Effective Date to a
location more than fifty (50) miles from such office, which relocation is not
approved by the Executive.

                           (d)     In the event of the Employee's voluntary
termination, then the Employee shall, at the request of the Board of the
Employer, continue as an employee of the Employer for an additional thirty (30)
day period after the Termination Date for the purpose of assisting the Employer
in locating and training a suitable replacement for the Employee. During such
additional period, the Employee shall be entitled to full compensation and
benefits and the Employee shall continue to be bound by all of the terms
contained herein. Any such extended term shall extend the Post-Termination
Period by an equal number of days.

                  B.       Termination With Cause.

                           (a)     The Employer (by act of its Board) may
terminate this Agreement immediately for "cause" by giving written notice to the
Employee. As used herein, the term "cause" shall mean the Employee's: (i)
addiction to illegal drugs; (ii) willful failure or refusal to perform his
duties hereunder after written notice from the Board and an opportunity to cure;
(iii) knowing acts of dishonesty which materially adversely affect the Employer;
(iv) indictment for a felony or crime involving moral turpitude, fraud,
embezzlement or misrepresentation. In the event that this Agreement is
terminated pursuant to this subsection (B), the Employee forfeits and shall not
be entitled to the Severance Package, or other benefits or bonus of any kind

                                       7
<PAGE>

whatsoever for any period after the Termination Date set forth in the notice
given by the Employer to the Employee.

                  C.       Disability.

                           (a)     If the Employee shall be disabled so as to be
unable to perform the essential functions of the Employee's then existing
position or positions under this Agreement, the Employer may remove the Employee
from any responsibilities and/or reassign the Employee to another position with
the Employer during the period of such disability. If the period of disability
extends for more than six (6) months, the Employer may terminate the Employee's
employment without further liability on the part of the Employer, except that
the Employee shall be entitled to the Severance Package. The Employer may elect,
at its sole discretion, to purchase a disability insurance package for the
Employee. In the event that the Employer so elects to purchase a disability
insurance package and the Employee subsequently becomes entitled to payments of
the disability insurance benefit, any payments pursuant to the Severance
Package, as defined in this Section 15, or payments of salary by the Employer
will be reduced by the amount of the disability insurance benefit payments
received by the Employee.

                           (b)     If any question shall arise as to whether
during any period the Employee is disabled so as to be unable to perform the
essential functions of the Employee's then existing position or positions, the
Employee may, and at the request of the Employer shall, submit to the Employer a
certification in reasonable detail by a physician selected by the Employer, to
whom the Employee or the Employee's guardian has no reasonable objection, as to
whether the Employee is so disabled or how long such disability is expected to
continue, and such certification shall, for the purposes of this Agreement, be
conclusive of the issue. The Employee shall cooperate with any reasonable
request of the physician in connection with such certification. If such question
shall arise and the Employee shall fail to submit such certification, the
Employer's determination of such issue shall be binding on the Employee. Nothing
in this Section 15(c) shall be construed to waive the Employee's rights, if any,
under existing law including, without limitation, the Family and Medical Leave
Act of 1993, 29 U.S.C. 2601, et seq. and the Americans with Disabilities Act, 42
U.S.C. 12101 et seq.

                  D.       Death or Retirement. The Employee's employment under
this Agreement will be deemed to have terminated without further liability on
the part of the Employer if the Employee dies or retires.

                  E.       Certain Termination Benefits. Unless otherwise
specifically provided in this Agreement or otherwise required by law, all
compensation and benefits payable to the Employee under this Agreement shall
terminate on the date of termination of the Employee's employment under this
Agreement.

                  F.       No Right to Continuing Employment. The Employee
agrees that nothing contained in this Agreement shall be construed to give the
Employee a right to continuing employment beyond the Termination Date.

                                       8
<PAGE>

         16.      Litigation and Regulatory Cooperation. During and after the
Employee's employment, the Employee shall cooperate fully with the Employer in
the defense or prosecution of any claims or actions now in existence or which
may be brought in the future against or on behalf of the Employer which relate
to events or occurrences that transpired while the Employee was employed by the
Employer. The Employee's full cooperation in connection with such claims or
actions shall include, but not be limited to, being available to meet with
counsel to prepare for discovery or trial and to act as a witness on behalf of
the Employer at mutually convenient times. During and after the Employee's
employment, the Employee also shall cooperate fully with the Employer in
connection with any investigation or review of any federal, state or local
regulatory authority as any such investigation or review relates to events or
occurrences that transpired while the Employee was employed by the Employer. The
Employer shall reimburse the Employee for any reasonable out-of-pocket expenses
incurred in connection with the Employee's performance of obligations pursuant
to this Section 16.

         17.      Injunction. The Employee agrees that it would be difficult to
measure any damages caused to the Employer which might result from any breach by
the Employee of the promises set forth in Section 8, and that in any event money
damages would be an inadequate remedy for any such breach. Accordingly, the
Employee agrees that if the Employee breaches, or proposes to breach, any
portion of this Agreement, the Employer shall be entitled, in addition to all
other remedies that it may have, to an injunction or other appropriate
preliminary equitable relief to restrain any such breach without showing or
proving any actual damage to the Employer.

         18.      No Assignment. The Employee acknowledges that the services to
be rendered by him pursuant to this Agreement are unique. Accordingly, the
Employee shall not assign any of his rights or delegate any of his duties or
obligations under this Agreement.

         19.      Severability. Subject only to the reformation of time,
geographical and occupational limitations as set forth in Section 20 hereof, all
of the terms and provisions contained in this Agreement are severable and, in
the event that any portion or provision of this Agreement (including, without
limitation, any portion or provision of any section of this Agreement) shall to
any extent be deemed unenforceable or invalid by a court of competent
jurisdiction, then the remainder of this Agreement, or the application of such
portion or provision in circumstances other than those as to which it is so
declared unenforceable or invalid, shall not be affected thereby, and each
portion and provision of this Agreement shall be valid and enforceable to the
fullest extent permitted by law.

         20.      Reformation of Time Geographical and Occupational Limitations.
In the event that any provision in this Agreement is held to be unenforceable by
a court of competent jurisdiction because it exceeds the maximum time,
geographical or occupational limitations permitted by applicable law, then such
provision(s) shall be and hereby are reformed to the maximum time, geographical
and occupational limitations as may be permitted by applicable law.

         21.      Specific Performance. Both parties recognize that the services
to be rendered under this Agreement by the Employee are special, unique and of
an extraordinary character, and

                                       9
<PAGE>

that in the event of breach by the Employee of the terms or conditions of this
Agreement to be performed by him, the Employer shall be entitled, if it so
elects, to institute and prosecute proceedings in any court of competent
jurisdiction, either at law or in equity, to obtain damages for any breach of
this Agreement to enforce the specific performance thereof by the Employee, or
to enjoin the Employee from engaging in such activity, but nothing contained
herein shall be construed to prevent such other remedy in the courts, in case of
any breach of this Agreement by the Employee, as the Employer may elect to
invoke.

         22.      Massachusetts Law: Choice of Forum. This Agreement shall be
governed, construed and interpreted by, and in accordance with, the laws of the
Commonwealth of Massachusetts, without reference to its principles of conflicts
of laws. Any actions concerning enforcement of this Agreement or in any way
relating to the subject matter of this Agreement shall be litigated only in
Massachusetts state or federal courts of proper jurisdiction and venue. Each
party hereto expressly agrees to submit to such jurisdiction and venue for the
purposes of this Agreement. Notwithstanding the foregoing, the Employer may seek
to enforce the Employee's covenants described in Sections 6, 7, 8 and 9 hereof
in any jurisdiction and venue in which the Employee then resides, breaches or
threatens to breach such covenants.

         23.      Entire Agreement. This Agreement constitutes the entire
agreement of the parties hereto, and replaces all prior agreements, promises,
representations and understandings between the Employer and the Employee
whatsoever concerning the limited subject matter hereof (other than the Stock
Plan and any related Stock Option Agreement entered into between the Employer
and the Employee). There are no other agreements, conditions or representations,
oral or written, express or implied, which form the basis for this Agreement.

         24.      Assignment; Successors and Assigns, Etc. Neither the Employer
nor the Employee may make any assignment of this Agreement or any interest
herein, by operation of law or otherwise, without the prior written consent of
the other party; provided, however, that the Employer may assign its rights
under this Agreement without the consent of the Employee in the event that the
Employer shall effect a reorganization, consolidate with or merge into any other
corporation, partnership, organization or other entity, or transfer all or
substantially all of its properties or assets to any other corporation,
partnership, organization or other entity. This Agreement shall inure to the
benefit of and be binding upon the Employer and the Employee, their respective
successors, executors, administrators, heirs and permitted assigns.

         25.      Modification. No waiver or modification of this Agreement or
of any covenant, condition, or limitation contained herein shall be valid unless
in a writing of subsequent date hereto and duly executed by the party to be
charged therewith and no evidence of any waiver or modification shall be offered
or received in evidence in any proceeding, arbitration, or litigation between
the parties hereto arising out of or affecting this Agreement, or the rights or
obligations of the parties hereunder, unless such waiver or modification is in
writing, duly executed as aforesaid. The parties further agree that the
provisions of this Section may not be waived except as herein set forth.

         26.      Section Headings. The section headings contained in this
Agreement are for convenience only, and shall in no manner be construed as part
of this Agreement.

                                       10
<PAGE>

         27.      Waiver of Breach. The waiver by either party of a breach or
violation of any provision of this Agreement shall not operate as, or be
construed to be, a waiver of any subsequent breach thereof.

         28.      Notices. Any and all notices required or permitted to be given
under this Agreement shall be sufficient if furnished in writing, sent by
certified or registered mail, return receipt requested to the party's address
set forth in the Prologue of this Agreement, or to such other address as such
party may specify in writing.

         29.      Counterparts. This Agreement may be executed in any number of
counterparts, each of which when so executed and delivered shall be taken to be
an original; but such counterparts shall together constitute one and the same
document.

         IN WITNESS WHEREOF, the parties have executed this Agreement on the day
and year here above first written.

MOLECULAR INSIGHT PHARMACEUTICALS, INC.

By:  /s/ David S. Barlow
     ---------------------------------------
Name: David S. Barlow
Title: Chairman & CEO

/s/ Norman D. LaFrance
--------------------------------------------
Norman D. LaFrance

                                       11
<PAGE>

                                   SCHEDULE A
            (As Amended from time to time pursuant to Paragraph 3(a))

                                Base Compensation

<TABLE>
<CAPTION>
--------------------------------------------------------------------------------
Annual Rate of Base
Compensation                 Agreed to by Employee         Agreed to by Employer
-------------------          ---------------------         ---------------------
--------------------------------------------------------------------------------
<S>                          <C>                           <C>
$325,000.00
--------------------------------------------------------------------------------
</TABLE>

(Must be initialed by both parties each time amended to be effective.)

Exhibit A --  Incentive Stock Option Grant

                                       12
<PAGE>

                                   SCHEDULE B

                               Relocation Package

         1.       The Employer will reimburse bona fide relocation expenses up
to a maximum amount of $150,000.00 based on the following:

         -        Reimbursement for expenses associated with direct-route
                  transportation to the Boston/Cambridge area that complies with
                  the Employer's travel policy.

         -        The cost of packing, moving, up to 90 days temporary storage,
                  and unloading of the Employee's household effects and using a
                  certified carrier of the employer's choice.

         -        House-hunting trips for the purpose of locating suitable
                  housing

         -        The reasonable cost of temporary housing for up to 90 days
                  upon arrival in the Boston area or $20,000.00 (grossed up)
                  lump sum if housing is not used.

         -        Closing costs (excluding points) on the purchase of a new home
                  up to 3% of the purchase price, if purchased within 6 months
                  of the Effective Date.

         -        Reimbursement of reasonable and customary closing costs,
                  including real estate commission not to exceed 6%, legal and
                  recording fees, title charges, transfer taxes, and documentary
                  stamps, etc. on the sale of Employee's existing home.

         2.       In addition to the foregoing, the Employer will provide a lump
sum allowance of $30,000.00 (grossed up) to cover additional relocation related
expenses.

                                       13exv4w1

 

Exhibit 4.1

US RSU AGREEMENT

NUANCE COMMUNICATIONS, INC.

STAND-ALONE

RESTRICTED STOCK UNIT AGREEMENT

	 	 	 	 	 	 	 
	(A)

	 	Name of Grantee:
	 	 
	 	 
	 

	 	 	 	 

	 	 
	(B)

	 	Credit Date:	 	 	 	 
	 

	 	 	 	 

	 	 
	(C)

	 	Number of Units:	 	 	 	 
	 

	 	 	 	 

	 	 
	(D)

	 	Effective Date:	 	 	 	 
	 

	 	 	 	 

	 	 

     THIS RESTRICTED STOCK UNIT AGREEMENT (the “Agreement”), is effective as of the date set forth
in Item D above (the “Effective Date”) between Nuance Communications, Inc., a Delaware corporation
(the “Company”) and the person named in Item A above (“Grantee”).

     THE PARTIES AGREE AS FOLLOWS:

	1.	 	Restricted Stock Units. Pursuant to terms and conditions set forth in this Agreement, the
Company hereby grants to the Grantee a number of restricted stock units set forth in Item C
above (the “Restricted Stock Units”).
	 
	2.	 	Company’s Obligation to Pay; Purchase Price. Each Restricted Stock represents the right to
receive a Share on the date it becomes vested. Unless and until the Restricted Stock Units
will have vested in the manner set forth in Section 4, the Grantee will have no right to
payment of any such Restricted Stock Units. Prior to actual payment of any Restricted Stock
Units, each Restricted Stock Unit will represent an unsecured obligation of the Company,
payable (if at all) only from the general assets of the Company.
	 
	3.	 	Definitions.

	 	(a)	 	“Administrator” means the Board or any committee of the Board that has been
designated by the Board to administer this Agreement.
	 
	 	(b)	 	“Board” means the Board of Directors of the Company.
	 
	 	(c)	 	“Cause” means (i) a material breach of the Employee Proprietary Information,
Inventions, and Non-Competition Agreement (or any similar agreement) between the
Grantee and the Company (or any direct or indirect Subsidiary of the Company), (ii)
conviction of or entry of a plea of guilty or nolo contendere to a felony, (iii)
conviction of any crime involving moral turpitude or dishonesty that causes, or is
likely to cause, material harm to the Company (or any direct or indirect Subsidiary of
the Company), (iv) willful act of personal dishonesty, fraud or misrepresentation,
taken by the Grantee in connection with the Grantee’s responsibilities as an Employee,
that causes, or is likely to cause, harm to the Company (or any direct or indirect
Subsidiary of the Company); (v) willful and continued failure of the Grantee to
substantially perform his or her principal duties and/or obligations of employment
(except by reason of Disability) after

 

 

US RSU AGREEMENT

(A) the Grantee has received a written demand for performance which specifically sets
forth the factual basis for the Company’s belief that the Grantee has not
substantially performed his or her principal duties and/or obligations of employment
and (B) the Grantee has been given at least 15 days to cure such deficiencies; or
(vi) intentional and material damage to the Company’s property or the property of
any direct or indirect Subsidiary of the Company.

	 	(d)	 	“Code” means the Internal Revenue Code of 1986, as amended.
	 
	 	(e)	 	“Common Stock” means the Common Stock of the Company.
	 
	 	(f)	 	“Consultant” means any person, including an advisor, engaged by the Company or
a Parent or Subsidiary to render services to such entity
	 
	 	(g)	 	“Director” means a member of the Board or a member of the Board of Directors of
any Parent or Subsidiary to render services to such entity.
	 
	 	(h)	 	“Disability” means total and permanent disability as defined in Section
22(e)(3) of the Code and the Grantee has become entitled to receive benefits under the
Company’s short and/or long-term disability policies, as they may be in effect from
time to time, as a result of such permanent disability.
	 
	 	(i)	 	“Employee” means an employee of the Company or any Parent or Subsidiary of the
Company. A Service Provider shall not cease to be an Employee in the case of (i) any
leave of absence approved by the Company or (ii) transfers between locations of the
Company or between the Company, its Parent, any Subsidiary of the Company, or any
successor.
	 
	 	(j)	 	“Parent” means a “parent corporation”, whether now or hereafter existing, as
defined in Section 424(e) of the Code.
	 
	 	(k)	 	“Service Provider” means an Employee, Director or Consultant.
	 
	 	(l)	 	“Share” means a share of the Common Stock, as adjusted in accordance with
Section 8 below.
	 
	 	(m)	 	“Subsidiary” means a “subsidiary corporation”, whether now or hereafter
existing, as defined in Section 424(f) of the Code.

	4.	 	Vesting. The Restricted Stock Units will vest in accordance with the terms and conditions
set forth in Exhibit A attached hereto. Notwithstanding the vesting terms and conditions set
forth in Exhibit A, in the event the Company (or the Subsidiary employing the Grantee, as
applicable) terminates the Grantee’s employment with the Company (or the Subsidiary employing
the Grantee, as applicable) without Cause, 100% of the then unvested Restricted Stock Units
will immediately vest, including any Restricted Stock Units that otherwise are to vest upon
the achievement of performance objectives.

 

 

US RSU AGREEMENT

	5.	 	Forfeiture upon Termination as Service Provider. Except as set forth in Section 4, if the
Grantee ceases to be a Service Provider for any or no reason, the then-unvested Restricted
Stock Units awarded by this Agreement will thereupon be forfeited at no cost to the Company
and the Grantee will have no further rights to acquire Shares with respect thereto.
	 
	6.	 	Payment After Vesting. Subject to Section 10, any Restricted Stock Units that vest in
accordance with Section 4 will be paid to the Grantee in whole Shares at the time or times set
forth in Section 2.
	 
	7.	 	Rights as Stockholder. Neither the Grantee nor any person claiming under or through the
Grantee will have any of the rights or privileges of a stockholder of the Company in respect
of any Shares deliverable hereunder unless and until certificates representing such Shares
will have been issued, recorded on the records of the Company or its transfer agents or
registrars, and delivered to the Grantee.
	 
	8.	 	Adjustment Upon Changes in Capitalization, Dissolution, Merger or Asset Sale.

	 	(a)	 	Changes in Capitalization. Subject to any required action by the
stockholders of the Company, the number and class of Shares that may be delivered under
this award of Restricted Stock Units shall be adjusted in order to prevent diminution
or enlargement of the benefits or potential benefits intended to be made available
under this Agreement for any dividend or other distribution (whether in the form of
cash, Shares, other securities, or other property), spin-off, increase or decrease in
the number of issued Shares resulting from a stock split, reverse stock split, stock
dividend, combination or reclassification of the Shares, any other increase or decrease
in the number of issued Shares effected without receipt of consideration by the Company
or other change in the corporate structure of the Company affecting the Shares occurs;
provided, however, that conversion of any convertible securities of the Company shall
not be deemed to have been “effected without receipt of consideration.” Such adjustment
shall be made by the Board, whose determination in that respect shall be final, binding
and conclusive. Except as expressly provided herein, no issuance by the Company of
            shares of stock of any class, or securities convertible into shares of stock of any
class, shall affect, and no adjustment by reason thereof shall be made with respect to,
the number of Shares subject to this award.
	 
	 	(b)	 	Dissolution or Liquidation. In the event of the proposed dissolution
or liquidation of the Company, the Administrator shall notify Grantee as soon as
practicable prior to the effective date of such proposed transaction. To the extent it
has not been previously vested, this award of Restricted Stock Units will terminate
immediately prior to the consummation of such proposed action.
	 
	 	(c)	 	Merger or Asset Sale. In the event of a merger of the Company with or
into another corporation, or the sale of substantially all of the assets of the
Company, this award of Restricted Stock Units to the extent it remains outstanding at
such time shall be assumed or an equivalent right substituted by the successor

 

 

US RSU AGREEMENT

corporation or a Parent or Subsidiary of the successor corporation. In the event
that the successor corporation refuses to assume or substitute for this award of
Restricted Stock Units, the Grantee will fully vest in this award of Restricted
Stock Units and the Shares issuable thereunder will be issued, even if the
Restricted Stock Units would not otherwise be vested and all vesting criteria will
be deemed achieved at target levels and all other terms and conditions met.

	9.	 	Tax Advice. The Company has made no warranties or representations to the Grantee with
respect to the income tax consequences of the transactions contemplated by the Agreement
pursuant to which the Restricted Stock Units have been issued and the Shares issuable
thereunder and the Grantee is in no manner relying on the Company or its representatives for
an assessment of such tax consequences. The Grantee acknowledges that the Grantee has not
relied and will not rely upon the Company or the Company’s counsel with respect to any tax
consequences related to the Restricted Stock Units or the ownership, purchase, or disposition
of the Shares issuable thereunder. The Grantee assumes full responsibility for all such
consequences and for the preparation and filing of all tax returns and elections which may or
must be filed in connection with the Restricted Stock Units and the Shares issuable
thereunder.
	 
	10.	 	Withholding of Taxes.

	 	(a)	 	Notwithstanding any contrary provision of this Agreement, no certificate
representing Shares may be released from the Company unless and until the Grantee shall
have delivered to the Company the full amount of any federal, state or local income or
other taxes which the Company may be required by law to withhold with respect to such
Shares. At the election of the Company, any federal, state and local withholding taxes
with respect to the Restricted Stock Units and/or the Shares issuable thereunder may be
paid by reducing the number of vested Shares actually paid to the Grantee.
	 
	 	(b)	 	At the Grantee’s election, the Company may deduct from any payment of
distribution of Shares the amount of any tax required by law to be withheld with
respect to issuance of Shares hereunder. The Grantee must inform the Company of his or
her preference for payment of his or her withholding tax obligations within 30 days of
receipt of the documentation. An election form is attached hereto as Exhibit B.

	11.	 	Assignment; Binding Effect. Subject to the limitations set forth in this Agreement, this
Agreement shall be binding upon and inure to the benefit of the executors, administrators,
heirs, legal representatives, and successors of the parties hereto; provided, however, that
the Grantee may not assign any of the Grantee’s rights under this Agreement.
	 
	12.	 	Damages. Grantee shall be liable to the Company for all costs and damages, including
incidental and consequential damages, resulting from a disposition of the Restricted Stock
Units or Shares issuable hereunder which are not in conformity with the provisions of this
Agreement.

 

 

US RSU AGREEMENT

	13.	 	Modifications to the Agreement. Modifications to this Agreement can be made only in an
express written contract executed by a duly authorized officer of the Company.
Notwithstanding anything to the contrary in this Agreement, the Company reserves the right to
revise this Agreement as it deems necessary or advisable, in its sole discretion and without
the consent of the Grantee, to comply with Section 409A of the Code or to otherwise avoid
imposition of any additional tax or income recognition under Section 409A of the Code in
connection to this award of Restricted Stock Units.
	 
	14.	 	Governing Law. This Agreement shall be governed by, and construed in accordance with, the
laws of the Commonwealth of Massachusetts excluding those laws that direct the application of
the laws of another jurisdiction.
	 
	15.	 	Notices. All notices and other communications under this Agreement shall be in writing.
Unless and until the Grantee is notified in writing to the contrary, all notices,
communications, and documents directed to the Company and related to the Agreement, if not
delivered by hand, shall be mailed, addressed as follows:

Nuance Communications, Inc.

One Wayside Road

Burlington, MA 01803

Attention: HR Director

Unless and until the Company is notified in writing to the contrary, all notices,
communications, and documents intended for the Grantee and related to this Agreement, if not
delivered by hand, shall be mailed to Grantee’s last known address as shown on the Company’s
books. Notices and communications shall be mailed by first class mail, postage prepaid;
documents shall be mailed by registered mail, return receipt requested, postage prepaid.
All mailings and deliveries related to the Agreement shall be deemed received when actually
received, if by hand delivery, and two business days after mailing, if by mail.

	16.	 	Arbitration. Any and all disputes or controversies arising out of this Agreement shall be
finally settled by arbitration conducted in Essex County in accordance with the then existing
rules of the American Arbitration Association, and judgment upon the award rendered by the
arbitrators may be entered in any court having jurisdiction thereof; provided that nothing in
this Section 16 shall prevent a party from applying to a court of competent jurisdiction to
obtain temporary relief pending resolution of the dispute through arbitration. The parties
hereby agree that service of any notices in the course of such arbitration at their respective
addresses as provided for in Section 15 shall be valid and sufficient.

	17.	 	No Rights to Restricted Stock Units, Shares, Options or Employment. Other than with respect
to the Restricted Stock Units, neither the Grantee nor any other person shall have any claim
or right to be issued Shares or granted an option to acquire Shares under this Agreement.
Having received the Restricted Stock Units shall not give the Grantee any right to receive any
other grant of options or other equity under any Company plan or

 

 

US RSU AGREEMENT

otherwise. The Grantee acknowledges and agrees that this Agreement, the transactions
contemplated hereunder and the vesting schedule set forth herein do not constitute an
express or implied promise of the Grantee’s continuation as a Service Provider for the
vesting period, for any period, or at all, and will not interfere with the Grantee’s right
or the right of the Company (or the Subsidiary employing or retaining the Grantee) to
terminate the Grantee’s status as a Service Provider at any time, with or without cause.

	18.	 	Entire Agreement. Company and Grantee agree that this Agreement (including its attached
Exhibits) is the complete and exclusive statement between Company and the Grantee regarding
its subject matter and supersedes all prior proposals, communications, and agreements of the
parties, whether oral or written, regarding the grant Restricted Stock Units and the Shares
issuable thereunder to Grantee.

	19.	 	Additional Conditions to Issuance of Shares. If at any time the Company will determine, in
its discretion, that the listing, registration or qualification of the Shares upon any
securities exchange or under any state or federal law, or the consent or approval of any
governmental regulatory authority is necessary or desirable as a condition to the issuance of
Shares to the Grantee, such issuance will not occur unless and until such listing,
registration, qualification, consent or approval will have been effected or obtained free of
any conditions not acceptable to the Company. Where the Company determines that the delivery
of the payment of any Shares will violate federal securities laws or other applicable laws,
the Company will defer delivery until the earliest date at which the Company reasonably
anticipates that the delivery of Shares will no longer cause such violation. The Company will
make all reasonable efforts to meet the requirements of any such state or federal law or
securities exchange and to obtain any such consent or approval of any such governmental
authority.

	20.	 	Administrator Authority. The Administrator will have the power to interpret this Agreement
and to adopt such rules for the administration, interpretation and application of this
Agreement as are consistent therewith and to interpret or revoke any such rules (including,
but not limited to, the determination of whether or not any Restricted Stock Units have
vested). All actions taken and all interpretations and determinations made by the
Administrator in good faith will be final and binding upon the Grantee, the Company and all
other interested persons. No member of the Administrator will be personally liable for any
action, determination or interpretation made in good faith with respect to this Agreement.

	21.	 	Captions. Captions provided herein are for convenience only and are not to serve as a basis
for interpretation or construction of this Agreement.

	22.	 	Agreement Severable. In the event that any provision in this Agreement will be held invalid
or unenforceable, such provision will be severable from, and such invalidity or
unenforceability will not be construed to have any effect on, the remaining provisions of this
Agreement.

 

 

US RSU AGREEMENT

     IN WITNESS WHEREOF, the parties have executed this Agreement as of the Effective Date.

	 	 	 	 	 
	 	NUANCE COMMUNICATIONS, INC.

 	 
	 	By:  	 	 
	 	 	Paul A. Ricci 	 
	 

     The Grantee hereby accepts and agrees to be bound by all of the terms and conditions of this
Agreement.

	 	 	 	 	 
	 	
 	 
	 	Grantee— [NAME] 	 
	 	 	 	 
	 

 

 

US RSU AGREEMENT

EXHIBIT A

VESTING TERMS AND CONDITIONS OF RESTRICTED STOCK UNITS

 

 

US RSU AGREEMENT

EXHIBIT B

TO: Grantee

FROM: Deborah E. Sheehan, Global Equity Manager

RE: Payment of Withholding Taxes Applicable to Restricted Stock Unit Awards
 

As you know, Nuance Communications, Inc. (“Company”) granted you an award of restricted stock units
(the “Award”). In connection with the Award, you will have taxable income at the time the Award
vests, or, if applicable, at the time shares of Company common stock (“Shares”) are issued pursuant
to the Award.

Under applicable law, withholding taxes are due and payable at the time the Shares are issued
pursuant to the Award. Before Company delivers to you any Shares under the Award, Company must
withhold applicable federal, state, local, foreign and other taxes (the “Withholding Tax”). The
current federal supplemental wage withholding rate for U.S. employees is twenty-five percent (25%).
In addition to the federal supplemental wage withholding rate, withholding for state and local
taxes may also be required, the rate of which will vary depending on where you live.

In connection with your Award, you agreed to make appropriate arrangements regarding the
Withholding Tax applicable to your Award.

Company is offering you the opportunity to elect one of two methods to satisfy your Withholding
Tax. Select one of the two methods of payment described below:

	 	 	 
	______

	 	Payment by Check. Our stock administration department will
contact you via e-mail with the amount of the Withholding Tax
due and payable. Please make your check payable to Nuance
Communications, Inc. and mail it to Nuance Communications,
Inc., Attention: Deborah E. Sheehan, One Wayside Road,
Burlington, MA 01803. You are required to satisfy your
Withholding Tax obligations by tendering to Company the amount
of the Withholding Tax due and payable the day after Company
notifies you of the amount.

	 
	______

	 	Retention of Shares by the Company. Company will retain the
number of Shares equal to the amount of minimum withholding
due and payable. Fractional Shares will not be retained to
satisfy any portion of the Withholding Tax. Accordingly, you
agree that in the event that the amount of Withholding Tax you
owe would result in a fraction of a Share being owed, that
amount will be satisfied by withholding the fractional amount
from your paycheck. If such amount is required to be
withheld, you expressly acknowledge that by checking this box
you are giving the

 

 

US RSU AGREEMENT

Company permission to withhold from your paycheck an amount equal to the remaining
Withholding Tax due and payable.

Please elect the method of payment that you wish to satisfy your Withholding Tax from the two
choices above, sign and date the form, and return it to the Deborah E. Sheehan at Nuance
Communications, Inc. You may either mail this election form to: Nuance Communications, Inc.,
Attention: Deborah E. Sheehan, One Wayside Road, Burlington, MA 01803 or fax it to 781-565-5553,
attn: Deborah E. Sheehan/Withholding Election.

By signing below, I understand (1) that Company will withhold an amount required by applicable law
to satisfy the minimum Withholding Tax applicable to my Award, and (2) agree to have such
Withholding Tax obligation satisfied by the method I checked above.

	 	 	 	 	 	 	 	 
	 

	 	 
	 	 	 	 	, 2007
	 

	 	 	 	 

	 	 

	 
	Grantee: [NAME]

	 	 	 	Date

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00120-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00120-of-00352.parquet"}]]