Document:

Resolution 12 of the General Meeting of the Shareholders of sanofi-aventis

 Exhibit 4.3 
 Resolution Number 12 of the General Meeting of the Shareholders of sanofi-aventis held on May 31, 2007 
 (Free
translation. French original prevails.) 
 TWELFTH RESOLUTION 
 Authorization to the Board of Directors to grant options to subscribe for or purchase shares 
 The General Meeting,
voting on the quorum and majority conditions for Extraordinary Meetings, having reviewed the Directors’ Report and Statutory Auditors’ Special Report: 
  

	1.	authorizes the Board of Directors, under articles L.225-177 to L.225-185 of the Commercial Code, to grant, on one or more occasions, in favor of members of the personnel to be
chosen by the Board of Directors from among the employees and corporate officers of the company or of companies or groupings related to the company, on the terms specified in article L.225-180 of said Code, options giving entitlement to subscribe
for new shares in the company to be issued in the form of an increase in its capital, and options giving entitlement to purchase shares in the company obtained by the company repurchasing its own shares on the terms laid down by the law;

  

	 2.
	 resolves that options to subscribe for or purchase shares granted by virtue of the present authorization may not give
entitlement to a total number of shares exceeding 2.5% of the share capital as of the day the decision is made by the Board of Directors, and that the aggregate par value of capital increases resulting from the exercise of options to subscribe for
shares granted under the present delegation will count towards the overall ceiling specified in section 3 of the 7th resolution of the present
meeting; 

  

	3.	resolves that the price payable on the exercise of the options to subscribe for or purchase shares will be set in accordance with the law by the Board of Directors on the day the
options are granted; such price may not be lower than the average of the first quoted market prices of the company’s shares on Eurolist by Euronext during the twenty trading sessions preceding the day on which the options to subscribe for
shares are granted. If the company carries out any of the transactions specified in article L.225-181 of the Commercial Code, the Board of Directors will, on the terms stipulated by the regulations then in force, take the necessary measures to
protect the interests of the grantees by adjusting the number of shares that may be obtained on exercise of options granted to grantees so as to take account of the impact of the transaction in question; 

  

	4.	duly notes that the present delegation entails the express waiver by the shareholders, in favor of the grantees of options to subscribe for shares, of their preemptive rights
relating to the shares that are to be issued as and when said options are exercised. The increase in the share capital resulting from the exercise of the options to subscribe for shares will be definitively completed by mere declaration that the
option is exercised accompanied by the subscription form and full payment, which may be made in cash or by offset of debts of the company; 

  

	5.	consequently, confers full powers on the Board of Directors to implement the present authorization, and in particular to: 

  

	 	•	 	 establish a list of grantees of options, showing the number of options granted to each; 

  

	 	•	 	 set the terms and conditions of the options, and in particular: 

	 	•	 	 the term of validity of the options, it being understood that the options must be exercised within a maximum period of 10 years; 

  

	 	•	 	 the exercise date(s) or period(s) of the options, it being understood that the Board of Directors may (a) bring forward the exercise date(s) or period(s) of
the options, (b) extend the exercisability of the options, or (c) amend the dates or periods during which shares obtained by exercise of options may not be transferred or converted into bearer shares; 

  

	 	•	 	 any clauses prohibiting immediate resale of some or all of the shares provided that the period for which the shares must be retained may not exceed three years from
exercise of the option; 

  

	 	•	 	 in the case of options granted to corporate officers, either (a) decide that the options may not be exercised by the grantees before they cease to hold office,
or (b) stipulate the quantity of shares that they are required to retain in registered form until they cease to hold office; 

  

	 	•	 	 where appropriate, limit, suspend, restrict or prohibit the exercise of options or the transfer or conversion into bearer shares of shares obtained by the exercise
of options during certain periods or with effect from certain events; such decision may relate to some or all of the options or shares or to some or all of the grantees; 

  

	 	•	 	 decide on the date, which may be retrospective, from which the new shares resulting from the exercise of options to subscribe for shares will rank for dividend;

  

	6.	resolves that the Board of Directors, with powers to subdelegate within the law, will have full powers to duly record the completion of capital increases to reflect the amount of
shares actually subscribed by the exercise of options to subscribe for shares, amend the bylaws accordingly, and, at its sole discretion and as it sees fit, charge the costs of the capital increases against the share premium arising thereon and
deduct from this premium the sums necessary to increase the legal reserve to one-tenth of the new share capital after each capital increase, and accomplish all formalities necessary for the listing of the securities thereby issued, make all
declarations with the relevant bodies and generally do all that is necessary; 

  

	7.	resolves that this authorization cancels with effect from this day any unused portion of any previous delegation to the Board of Directors of authority to grant options to subscribe
for or purchase shares. It is granted for a period of twenty-six months from this day.Rules and Regulations of Sanofi-Aventis Stock Option Plan 2007

 Exhibit 4.4 
 Rules and Regulations of Sanofi-Aventis Stock Option Plan 2007 
 December
2007                 
 STOCK OPTION SUBSCRIPTION PLAN
OF SANOFI-AVENTIS 
 RULES OF THE 7TH PLAN 
 ********** 
  

					
		  	 1.      PARTICIPANTS
  
 2.      DURATION OF THE PLAN

  
 3.      EXERCISE PRICE
  
 4.      STOCK OPTION EXERCISE
  
 5.      SALE OF SHARES
  
 6.      SHARE
RIGHTS
  
 7.      OPTION PRICE ADJUSTMENT
  
 8.      FOREIGN PARTICIPANTS
	  	

 Free Translation of French version 
 December 2007 
 The French version prevails 

 The Board of Directors of sanofi-aventis was authorized by a General Meeting of its Shareholders held on May 31,
2007, according to Articles L.225-177 to L.225-185 of the French Commercial Code to set up stock option purchase or subscription plans for sanofi-aventis and companies of the sanofi-aventis group. By sanofi-aventis group we mean all companies or
groupings of economic interest defined by Article L.225-180 of the aforementioned code. 
 Following the proposal of its Chairman, the Board of Directors has
laid down the following rules of the stock option subscription plan with effect from December 13, 2007. 
  

	1.	PARTICIPANTS 

 Upon the recommendation of the
Chairman of sanofi-aventis acting upon the advice of the Compensation, Appointments and Governance Committee, the grant of options to subscribe shares of sanofi-aventis to a list of identified employees and corporate officers and the number of
options granted to each such participants is approved by the Board of Directors. 
 The rights granted are not transferable unless the options
are exercised. 
  

	2.	DURATION OF THE PLAN 

 Sanofi-aventis’
Stock Option Plan has a duration of ten years from the Board of Directors held on December 13, 2007. It will expire on December 13, 2017. 
  

	3.	EXERCISE PRICE 

 The stock option exercise
price was set by the Board of Directors on December 13, 2007 at 62.33 € corresponding to the average of the first quoted market prices of the company’s shares on Eurolist by Euronext Paris during the twenty trading sessions
preceding that day, without any rebate, subject to price adjustments in case of transaction on the share capital (see below article 7). 
  

	4.	STOCK OPTION EXERCISE 

 The exercise of the
options, also called “exercise of the options to subscribe shares” is not allowed during the first four years following the Board of Directors’ approval on December 13, 2007. 
 The options can be exercised, on one or more occasions as the participants see fit, at any time between December 14, 2011 and December 13, 2017
inclusive. Thereafter, the options will lapse. 
 Unless otherwise decided by the General Management of the Company in exceptional cases, any
participant irrevocably loses his/her rights to exercise his/her options in the following cases: 
  

	 	•	 	 In the event of resignation before the exercise date. Revocation of option rights takes effect on the day of notice of the resignation; and

	 	•	 	 In the event of dismissal for serious or gross misconduct. Revocation of option rights takes effect on the day of notice of the dismissal.

 The Company reserves the right to temporarily suspend the exercise of the options, in particular in the event of
financial transactions affecting the share capital of sanofi-aventis. 
 Exceptions : 
  

	 	4.1	If a participant retires or takes early retirement, at normal retirement age or earlier or later with the agreement of the Company, he/she keeps his/her option rights until
their expiration, that is December 13, 2017. 

  

	 	4.2	Notwithstanding the four-year period mentioned under Article 4, Paragraph 1, if an employee becomes disabled, and such disability meets the conditions of the second and third
categories as defined by Article L.341-4 of the French Social Security Code, the participant may exercise his/her options. The participant keeps his/her option rights until their expiration, that is December 13, 2017.

  

	 	4.3	Notwithstanding the four-year period mentioned under Article 4, Paragraph 1, if an employee dies during the option period, his/her heirs can exercise the options during the six
month period following the date of death. 

  

	5.	SALE OF SHARES 

 The sale of the shares
through the exercise of the options is possible from December 14, 2011. 
 However, any participant mentioned under article 4.2 or the heirs of a
participant who has died mentioned under article 4.3 above are able to sell the corresponding shares before the end of the four year holding period. 
  

	6.	SHARE RIGHTS 

 The participant will have rights to the shares that have been subscribed for upon exercise of the options from the first day of the year during which they have been subscribed. If he/she exercises his/her option
between 1st January and the date on which the share becomes ex-dividend for the dividend relating to the previous year, the beneficiary will not be
entitled to the dividend paid in the current year relating to the previous year; he/she will be entitled to the dividend paid in the following year relating to the current year. 
  

	7.	OPTION PRICE ADJUSTMENT 

 In the event of a
redemption or reduction of share capital, a change in the allocation of profits, a consideration-free issue of shares, an increase in share capital by incorporation of reserves, profits or share premium, a distribution of reserves, or any issue of
equity instruments that includes subscription rights reserved for the 

 
shareholders, the exercise price and the number of shares to which an option gives right will be adjusted in order to take into account such issuance or
other capital transaction. 
 If such a situation is covered by existing law or regulation, such law or regulation shall be applied.

 If such a situation is not covered by existing law or regulation, the General Meeting of Shareholders or the Board of Directors when
deciding to conduct such securities issuance or other capital transaction may adopt any adjustment measures necessary to protect the rights of the holders of the stock-options, using by analogy the rules and regulations which would govern similar
cases. 
  

	8.	FOREIGN PARTICIPANTS 

 Some specific
arrangements for the exercise of subscription options will be notified to foreign participants on a case by case basis. Indeed, in some foreign countries, local regulations particularly those relating to tax and social security require adjustments
to the general terms described in these rules. 
 The participant employees of American companies of the Group will have the possibility to
convert their ordinary shares into American Depositary Receipts (“ADRs”) on exercise of their options. 
 **********

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