Document:

Exhibit 10.6

 

Third AMENDMENT
TO Promissory note

 

THIS
Third Amendment (THE “SECOND AMENDMENT”) DATED July 27, 2018,
shall amend the Promissory note (THE “NOTE”) dated AS OF september 24,
2014 and amended on july 27, 2015 (the “first amendment”), and July 20, 2017 (The “Second Amendment”) AMONG
NON-INVASIVE MONITORING SYSTEMS, INC. (THE “MAKER”) AND JANE HSIAO (THE “PAYEE”) AS NOTED BELOW. THE NOTE,
THE FIRST AMENDMENT, THE SECOND AMENDMENT, AND THE THIRD AMENDMENT SHALL BE REFERRED TO AS THE AMENDED NOTE.

 

RECITALS

 

WHEREAS, Maker and
Payee (collectively, the “Parties”) are parties to the Note which became effective on September 24, 2014;

 

WHEREAS, on July
20, 2017, the Parties amended the Note to extend the Maturity Date from July 31, 2017 until July 31, 2018; and

 

WHEREAS, the Parties
desire to amend the Note to extend the Maturity Date from July 31, 2018 until July 31, 2020.

 

NOW THEREFORE, in
consideration of the mutual covenants and promises contained in the Note and this Third Amendment and other good and valuable consideration,
the receipt and sufficiency of which are hereby acknowledged, the Parties agree as follows:

 

AMENDMENT

 

1. Section
1 of the Note is hereby amended and restated in its entirety as follows:

 

The principal amount of the loan evidenced
hereby, together with any accrued and unpaid interest, and any and all unpaid costs, fees and expenses accrued, shall be due and
payable on July 31, 2020 (the “Maturity Date”).

 

2. Governing Law.
This Third Amendment shall be governed by the laws of the State of Florida without regard to its conflict of laws rules or principles.

 

3. Amendments. Except
as expressly amended hereby, the Note shall remain unmodified and in full force and effect.

 

4. Entire Agreement.
This Third Amendment and the Note constitute the entire agreement of the Parties with respect to the subject matter hereof and
supersede all prior understandings and writings between the Parties relating thereto.

 

    	 

    	 

     

5. Interpretation.
Any capitalized terms used in this Third Amendment but not otherwise defined shall have the meaning provided in the Note.

 

6. Counterparts.
This Third Amendment may be executed manually, electronically in Adobe® PDF file format, or by facsimile by the Parties, in
any number of counterparts, each of which shall be considered one and the same amendment and shall become effective when a counterpart
hereof shall have been signed by each of the Parties and delivered to the other Party.

 

IN WITNESS WHEREOF,
Borrower has duly executed this Third Amendment to the Note and Security Note as of the 27th day of July, 2018.

 

	 	 	 	NON-INVASIVE MONITORING SYSTEMS, INC. 
	 	 	 	 	 
	 	 	 	By:	
        /s/ James J. Martin

        

	 	 	 	Name:	
        James J. Martin

        

	 	 	 	Title:	
        Chief Financial Officer

        

	 	 	 	 	 
	Agreed and Accepted:	 	 	 
	 	 	 	 	 
	
        By:

        
	/s/ Jane Hsiao, Ph.D.	 	 	 
	Name:	
        Jane Hsiao, Ph.D.Exhibit 10.7

 

Third AMENDMENT
TO Promissory note

 

THIS
Third Amendment (THE “THIRD AMENDMENT”) DATED July 27, 2018,
shall amend the Promissory note (THE “NOTE”) dated AS OF FEBRUARY 2,
2015 and amended on july 27, 2015 (the “first amendment”), AND July 20, 2017 (THE “SECOND AMENDMENT”) AMONG
NON-INVASIVE MONITORING SYSTEMS, INC. (THE “MAKER”) AND JANE HSIAO (THE “PAYEE”) AS NOTED BELOW. THE NOTE,
THE FIRST AMENDMENT, THE SECOND AMENDMENT, AND THE THIRD AMENDMENT SHALL BE REFERRED TO AS THE AMENDED NOTE.

 

RECITALS

 

WHEREAS, Maker and
Payee (collectively, the “Parties”) are parties to the Note which became effective on February 2, 2015; and

 

WHEREAS, on July
20, 2017, the Parties amended the Note to extend the Maturity Date from July 31, 2017 until July 31, 2018; and

 

WHEREAS, the Parties
desire to amend the Note to extend the Maturity Date from July 31, 2018 until July 31, 2020.

 

NOW THEREFORE, in
consideration of the mutual covenants and promises contained in the Note and this Third Amendment and other good and valuable consideration,
the receipt and sufficiency of which are hereby acknowledged, the Parties agree as follows:

 

AMENDMENT

 

1. Section
1 of the Note is hereby amended and restated in its entirety as follows:

 

The principal amount of the loan evidenced
hereby, together with any accrued and unpaid interest, and any and all unpaid costs, fees and expenses accrued, shall be due and
payable on July 31, 2020 (the “Maturity Date”).

 

2. Governing Law.
This Third Amendment shall be governed by the laws of the State of Florida without regard to its conflict of laws rules or principles.

 

3. Amendments. Except
as expressly amended hereby, the Note shall remain unmodified and in full force and effect.

 

4. Entire Agreement.
This Third Amendment and the Note constitute the entire agreement of the Parties with respect to the subject matter hereof and
supersede all prior understandings and writings between the Parties relating thereto.

 

    	 

    	 

     

5. Interpretation.
Any capitalized terms used in this Third Amendment but not otherwise defined shall have the meaning provided in the Note.

 

6. Counterparts.
This Third Amendment may be executed manually, electronically in Adobe® PDF file format, or by facsimile by the Parties, in
any number of counterparts, each of which shall be considered one and the same amendment and shall become effective when a counterpart
hereof shall have been signed by each of the Parties and delivered to the other Party.

 

IN WITNESS WHEREOF,
Borrower has duly executed this Third Amendment to the Note and Security Note as of the 27th day of July, 2018.

 

	 	 	 	NON-INVASIVE MONITORING SYSTEMS, INC. 
	 	 	 	 	 
	 	 	 	
        By:

        
	/s/ James J. Martin
	 	 	 	
        Name:

        
	James J. Martin
	 	 	 	Title:	
        Chief Financial Officer

        

	 	 	 	 	 
	Agreed and Accepted:	 	 	 
	 	 	 	 	 
	By:	
        /s/ Jane Hsiao, Ph.D.

        
	 	 	 
	
        Name:

        
	Jane Hsiao, Ph.D.Exhibit 10.8

 

third AMENDMENT
TO Promissory note

 

THIS
third Amendment (THE “THIRD AMENDMENT”) DATED July 27, 2018,
shall amend the Promissory note (THE “NOTE”) dated AS OF April 16, 2015
and amended on july 27, 2015 (“the first amendment”), AND JULY 20, 2017 (THE “SECOND AMENDMENT”) AMONG
NON-INVASIVE MONITORING SYSTEMS, INC. (THE “MAKER”) AND FROST GAMMA INVESTMENTS TRUST (THE “PAYEE”) AS
NOTED BELOW. THE NOTE, THE FIRST AMENDMENT, THE SECOND AMENDMENT, AND THE THIRD AMENDMENT SHALL BE REFERRED TO AS THE AMENDED NOTE.

 

RECITALS

 

WHEREAS, Maker and
Payee (collectively, the “Parties”) are parties to the Note which became effective on April 16, 2015; and

 

WHEREAS, on July
20, 2017, the Parties amended the Note to extend the Maturity Date from July 31, 2017 until July 31, 2018; and

 

WHEREAS, the Parties
desire to amend the Note to extend the Maturity Date from July 31, 2018 until July 31, 2020.

 

NOW THEREFORE, in
consideration of the mutual covenants and promises contained in the Note and this Third Amendment and other good and valuable consideration,
the receipt and sufficiency of which are hereby acknowledged, the Parties agree as follows:

 

AMENDMENT

 

1. Section
1 of the Note is hereby amended and restated in its entirety as follows:

 

The principal amount of the loan evidenced
hereby, together with any accrued and unpaid interest, and any and all unpaid costs, fees and expenses accrued, shall be due and
payable on July 31, 2020 (the “Maturity Date”).

 

2. Governing Law.
This Third Amendment shall be governed by the laws of the State of Florida without regard to its conflict of laws rules or principles.

 

3. Amendments. Except
as expressly amended hereby, the Note shall remain unmodified and in full force and effect.

 

4. Entire Agreement.
This Third Amendment and the Note constitute the entire agreement of the Parties with respect to the subject matter hereof and
supersede all prior understandings and writings between the Parties relating thereto.

 

    	 

    	 

     

5. Interpretation.
Any capitalized terms used in this Third Amendment but not otherwise defined shall have the meaning provided in the Note.

 

6. Counterparts.
This Third Amendment may be executed manually, electronically in Adobe® PDF file format, or by facsimile by the Parties, in
any number of counterparts, each of which shall be considered one and the same amendment and shall become effective when a counterpart
hereof shall have been signed by each of the Parties and delivered to the other Party.

 

IN WITNESS WHEREOF,
Borrower has duly executed this Third Amendment to the Note and Security Note as of the 27th day of July, 2018.

 

	 	 	 	NON-INVASIVE MONITORING SYSTEMS, INC. 
	 	 	 	 	 
	 	 	 	By:	/s/ James J. Martin
	 	 	 	Name:	James J. Martin
	 	 	 	Title:	Chief Financial Officer
	 	 	 	 	 
	Agreed and Accepted:	 	 	 
	 	 	 	 	 
	FROST GAMMA INVESTMENTS TRUST	 	 	 
	 	 	 	 	 
	By:	/s/ Phillip Frost, M.D.	 	 	 
	Name:	Phillip Frost, M.D.	 	 	 
	Title:	TrusteeExhibit 10.9

 

SECOND AMENDMENT
TO Promissory note

 

THIS
SECOND Amendment (THE “SECOND AMENDMENT”) DATED July 27, 2018,
shall amend the Promissory note (THE “NOTE”) dated AS OF August 12,
2015 AND AMENDED ON JULY 20, 2017 (THE “FIRST AMENDMENT”) AMONG NON-INVASIVE MONITORING SYSTEMS, INC. (THE “MAKER”)
AND frost gamma investments trust (THE “PAYEE”) AS NOTED BELOW. THE
NOTE, THE FIRST AMENDMENT, AND THE SECOND AMENDMENT SHALL BE REFERRED TO AS THE AMENDED NOTE.

 

RECITALS

 

WHEREAS, Maker and
Payee (collectively, the “Parties”) are parties to the Note which became effective on August 12, 2015; and

 

WHEREAS, on July
20, 2017, the Parties amended the Note to extend the Maturity Date from July 31, 2017 until July 31, 2018; and

 

WHEREAS, the Parties
desire to amend the Note to extend the Maturity Date from July 31, 2018 until July 31, 2020.

 

NOW THEREFORE, in
consideration of the mutual covenants and promises contained in the Note and this Second Amendment and other good and valuable
consideration, the receipt and sufficiency of which are hereby acknowledged, the Parties agree as follows:

 

AMENDMENT

 

1. Section
1 of the Note is hereby amended and restated in its entirety as follows:

 

The principal amount of the loan evidenced
hereby, together with any accrued and unpaid interest, and any and all unpaid costs, fees and expenses accrued, shall be due and
payable on July 31, 2020 (the “Maturity Date”).

 

2. Governing Law.
This Second Amendment shall be governed by the laws of the State of Florida without regard to its conflict of laws rules or principles.

 

3. Amendments. Except
as expressly amended hereby, the Note shall remain unmodified and in full force and effect.

 

4. Entire Agreement.
This Second Amendment and the Note constitute the entire agreement of the Parties with respect to the subject matter hereof and
supersede all prior understandings and writings between the Parties relating thereto.

 

    	 

    	 

     

5. Interpretation.
Any capitalized terms used in this Second Amendment but not otherwise defined shall have the meaning provided in the Note.

 

6. Counterparts.
This Second Amendment may be executed manually, electronically in Adobe® PDF file format, or by facsimile by the Parties, in
any number of counterparts, each of which shall be considered one and the same amendment and shall become effective when a counterpart
hereof shall have been signed by each of the Parties and delivered to the other Party.

 

IN WITNESS WHEREOF,
Borrower has duly executed this Second Amendment to the Note and Security Note as of the 27th day of July, 2018.

 

	 	 	 	NON-INVASIVE MONITORING SYSTEMS, INC. 
	 	 	 	 	 
	 	 	 	By:	/s/ James J. Martin
	 	 	 	Name:	James J. Martin
	 	 	 	Title:	Chief Financial Officer
	 	 	 	 	 
	Agreed and Accepted:	 	 	 
	 	 	 	 	 
	FROST GAMMA INVESTMENTS TRUST	 	 	 
	 	 	 	 	 
	By:	/s/ Phillip Frost, M.D.	 	 	 
	Name: 	Phillip Frost, M.D.	 	 	 
	Title:	Trustee

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