Document:

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                              AMENDED AND RESTATED

                           WARRANT PURCHASE AGREEMENT

                                      Among

                            HORIZON PHARMACIES, INC.

                                       And

                               McKESSON HBOC, INC.

                            Dated as of May 14, 1999

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                                TABLE OF CONTENTS

<TABLE>
<CAPTION>
SECTION                                                HEADING                                                 PAGE

<S>                                                                                                            <C>
SECTION 1. CERTAIN DEFINITIONS AND TERMS..........................................................................1
         SECTION 1.1       DEFINITIONS............................................................................1

SECTION 2. AUTHORIZATION OF WARRANTS..............................................................................3

SECTION 3. SALE AND PURCHASE OF WARRANTS..........................................................................4

SECTION 4. EXERCISE OF WARRANTS AND DETERMINATION OF SHARES.......................................................4

SECTION 5. WARRANT ISSUE DATE AND CONDITIONS TO ISSUANCE..........................................................4

SECTION 6. REPRESENTATIONS AND WARRANTIES.........................................................................5
         SECTION 6.1       PURCHASE FOR INVESTMENT................................................................5
         SECTION 6.2       SOURCE OF FUNDS........................................................................5

SECTION 7. TRANSFER; REGISTRATION RIGHTS..........................................................................5
         SECTION 7.1       RESTRICTIONS ON TRANSFERABILITY........................................................5
         SECTION 7.2       NOTICE OF PROPOSED TRANSFER; REGISTRATION NOT REQUIRED.................................5
         SECTION 7.3       REQUIRED REGISTRATION..................................................................6
         SECTION 7.4       CONDITIONS TO REQUIRED REGISTRATION...................................................11
         SECTION 7.5       INCIDENTAL REGISTRATIONS..............................................................11
         SECTION 7.6       UNDERWRITTEN OFFERINGS................................................................12
         SECTION 7.7       EXPENSES; RELIANCE....................................................................12
         SECTION 7.8       INDEMNIFICATION AND CONTRIBUTION......................................................13
         SECTION 7.9       ADDITIONAL REGISTRATION RIGHTS........................................................15
         SECTION 7.10      RESTRICTIVE LEGENDS...................................................................15
         SECTION 7.11      STOCK EXCHANGE LISTING................................................................16
         SECTION 7.12      MISCELLANEOUS.........................................................................16

SECTION 8. REDEMPTION OF WARRANTS................................................................................16

SECTION 9. LOST, STOLEN WARRANTS, ETC............................................................................16

SECTION 10. RESTRICTIONS ON CAPITAL STRUCTURE....................................................................17

SECTION 11. INDEX AND CAPTIONS...................................................................................17

SECTION 12. MISCELLANEOUS........................................................................................17
         SECTION 12.1      NOTICES...............................................................................17
         SECTION 12.2      SUCCESSORS AND ASSIGNS................................................................17
         SECTION 12.3      SEVERABILITY..........................................................................17
         SECTION 12.4      GOVERNING LAW.........................................................................18
         SECTION 12.5      AMENDMENTS............................................................................18
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                                       i.
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Schedule A        --        Notice and Payment Instructions

Exhibit A         --        Warrant

                                       ii.
<PAGE>

                 AMENDED AND RESTATED WARRANT PURCHASE AGREEMENT

         THIS AMENDED AND RESTATED WARRANT PURCHASE AGREEMENT (this "AGREEMENT")
is entered into as of May 14, 1999, between HORIZON PHARMACIES, INC., a Delaware
corporation ("COMPANY"), and McKESSON HBOC, INC., a Delaware corporation
formerly known as McKesson Corporation ("MCKESSON").

         On July 2, 1998, Company issued its Warrant to purchase 101,500 shares
of Common Stock of Company to McKesson in connection with and as a condition to
the Loans. Such Warrants were issued pursuant to a Warrant Purchase Agreement
dated as of July 2, 1998 between Company and McKesson (the "Original
Agreement"). In consideration of certain amendments and waivers to the Credit
Agreement, Company has agreed to amend and restate the Original Agreement and to
issue new Warrants in exchange for the Warrants issued on July 2, 1998, and to
issue additional Warrants both concurrently with the execution and delivery
hereof and upon the satisfaction of certain conditions. In consideration of the
purchase by McKesson of the Warrants and of the credit facilities extended and
to be extended to Company, Company is willing to offer McKesson the rights
described herein, including, without limitation, registration rights and rights
of indemnity and other rights and privileges relating to the Warrants and the
Restricted Shares and Underlying Shares, all as more specifically set forth
herein.

         NOW, THEREFORE, for and in consideration of the foregoing and the
mutual covenants herein contained, the parties hereto agree that the Original
Agreement is hereby amended and restated to read in full as follows:

SECTION 1. CERTAIN DEFINITIONS AND TERMS.

         SECTION 1.1 DEFINITIONS. Terms not otherwise defined herein shall have
the respective meanings assigned thereto in the Credit Agreement. As used
herein, the following terms have the meanings indicated:

         "BUSINESS DAY" shall mean any day other than a Saturday, a Sunday or a
day on which commercial banks in Princeton, Texas, or San Francisco, California,
are required or authorized to be closed.

         "CERTIFICATE OF INCORPORATION" shall mean the Certificate of
Incorporation of Company as filed with the Delaware Secretary of State on April
27, 1998, without further amendment or modification thereto except as permitted
pursuant to the terms of this Agreement or the Warrant.

         "CLOSING DATE" means the date on which all conditions precedent set
forth in Section 4.1 of the Credit Agreement have been satisfied or waived by
McKesson.

         "CODE" means the Internal Revenue Code of 1986, as amended from time to
time, and the rules and regulations promulgated thereunder from time to time.

         "COMMISSION" means the Securities and Exchange Commission, or any other
federal agency at the time administering the Securities Act or the Trust
Indenture Act of 1939, as amended, as the case may be.

                                       1.
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         "COMMON STOCK" means the shares of common stock, par value of $0.01 per
share, of Company described in the Certificate of Incorporation.

         "CREDIT AGREEMENT" means that certain Credit Agreement dated as of July
2, 1998 between Company and McKesson, as it may be amended from time to time.

         "CUTBACK DETERMINATION" is defined in SECTION 7.3(a).

         "DEMAND REGISTRATION" is defined in SECTION 7.3(a).

         "ERISA" means the Employee Retirement Income Security Act of 1974, as
amended from time to time, and the rules and regulations promulgated thereunder
from time to time in effect.

         "EXERCISE PERIOD" means the period from but excluding on the fifteenth
day after the First Anniversary to and including the Expiration Date.

         "EXISTING WARRANT AGREEMENTS" means (i) the Warrant Agreement dated
November 7, 1997 between Company and ComVest Partners, Inc., (ii) the Warrant
Agreement dated July 11, 1997 between Company and Capital West Securities, Inc.
and ComVest Partners, Inc. and (iii) the Securities Purchase Agreement dated
June 15, 1998 among Company, on the one hand, and Quantum Partners LDC, Collins
Capital Diversified Fund, L.P., White Rock Capital Partners, L.P., White Rock
Capital Offshore, Ltd., Legion Strategies Limited, Caxton International Limited
and White Rock Capital Management, L.P. (#10), in each case excluding any
amendments thereto not approved in writing by a majority of the Holders.

         "EXPIRATION DATE" as to any Warrant means the date and time specified
as the "Expiration Date" in such Warrant.

         "FIRST ANNIVERSARY" means the first anniversary of the Closing Date.

         "HOLDER" means any beneficial owner of (i) any Restricted Share, or
(ii) any Warrant, in each case as the context may require.

         "INCIDENTAL CUTBACK DETERMINATION" is defined in SECTION 7.5.

         "INITIAL WARRANT ISSUE DATE" is defined in SECTION 5.

         "PERMITTED INCIDENTAL REGISTRATION" means the registration of
Securities of another Person pursuant to the rights granted by the Company under
the Existing Warrant Agreements or the Registration Rights Agreement dated June
15, 1998 among Company, on the one hand, and Quantum Partners LDC, Collins
Capital Diversified Fund, L.P., White Rock Capital Partners, L.P., White Rock
Capital Offshore, Ltd., Legion Strategies Limited, Caxton International Limited
and White Rock Capital Management, L.P. (#10), in each case excluding any
amendments thereto not approved in writing by a majority of the Holders.

         "PERSON" means an individual, partnership, corporation, trust or
unincorporated organization, or a government or agency or political subdivision
thereof.

                                       2.
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         "RESTRICTED SHARES" means the shares of Common Stock of Company issued
upon the exercise of any of the Warrants and evidenced by a certificate required
to bear the legend specified in SECTION 7.10.

         "SECOND WARRANT ISSUE DATE" is defined in SECTION 5.

         "SECURITIES ACT" means the Securities Act of 1933, as amended, or any
similar federal statute, and the rules and regulations promulgated thereunder,
all as the same shall be in effect at the time.

         "SECURITY" or "SECURITIES" shall have the same meaning as in Section
2(1) of the Securities Act.

         "THIRD AMENDMENT TO CREDIT AGREEMENT" means that certain Third
Amendment to Credit Agreement and Limited Waiver dated as of even date herewith
between Company and McKesson.

         "UNDERLYING SHARES" means the shares of Common Stock of Company
issuable upon exercise of any of the Warrants in accordance with the Warrants
and this Agreement, and any references contained herein to a Holder or Holders
of any Underlying Shares shall be deemed to refer to the Holder of the Warrants
relating thereto.

         "WARRANT ISSUE DATE" is defined in SECTION 5.

         "WARRANT SHARES" means the shares of Common Stock issued upon exercise
of the Warrants.

         "WARRANTS" is defined in SECTION 2.

SECTION 2. AUTHORIZATION OF WARRANTS.

         In consideration of, and as an inducement to, McKesson's entering into
the Third Amendment to Credit Agreement and to continue to extend credit to
Company under the Credit Agreement, Company will authorize the issuance and sale
of, and Company agrees to deliver to McKesson on the Warrant Issue Dates, one or
more warrants (all warrants being delivered to McKesson being referred to
collectively as the "WARRANTS") substantially in the form attached hereto as
Exhibit A to purchase the number of shares of Common Stock of Company as set
forth in SECTION 4 of this Agreement for the consideration set forth in the
Warrants. The number of shares which may be purchased upon the exercise of the
Warrants and the price per share are subject to adjustment in the manner and on
the terms and conditions set forth in the Warrants.

         The rights, powers and terms of and relating to the Common Stock will
be provided for in the Certificate of Incorporation, and as otherwise provided
by the Delaware General Corporation Law of the State of Delaware. In addition,
the Warrants and the shares of Common Stock issuable upon exercise thereof are
subject to the terms and provisions specified in this Agreement.

                                       3.
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SECTION 3. SALE AND PURCHASE OF WARRANTS.

         Subject to the terms and conditions of this Agreement, Company will
issue and sell to McKesson, and McKesson will purchase from Company, at the
relevant Warrant Issue Date, the following installments of Warrants:

                  (i) On the Initial Warrant Issue Date, Warrants for 101,500
         shares of Common Stock of Company with an initial Exercise Price of
         $5.71 in exchange for and upon surrender of the Warrants issued on July
         2, 1998;

                  (ii) On the Initial Warrant Issue Date, additional Warrants
         for 100,000 shares of Common Stock of Company with an initial Exercise
         Price of $5.71; and

                  (iii) On the Second Warrant Issue Date, Warrants for 50,000
         shares of Common Stock of Company with an Exercise Price equal to the
         average closing price of Common Stock of Company for the five business
         day period commencing on the date of the Approval Notice.

The aggregate purchase price for the Warrants shall be McKesson's execution and
delivery of the Credit Agreement.

         Company and McKesson agree that the per share value of the Warrants for
tax purposes is $2.55. Company and McKesson agree to report the transaction in a
manner consistent with this paragraph.

SECTION 4. EXERCISE OF WARRANTS AND DETERMINATION OF SHARES.

         The Warrants shall be exercisable from time to time at any time during
the Exercise Period on an aggregate basis into the number shares of Common Stock
specified in the Warrants, subject to adjustment in the manner and on the terms
and conditions set forth in the Warrants.

SECTION 5. WARRANT ISSUE DATE AND CONDITIONS TO ISSUANCE.

         The issuance of the first two installments of Warrants under clauses
(i) and (ii) of Section 3 shall occur simultaneously with the execution and
delivery of the Third Amendment to Credit Agreement by the parties or on such
other Business Day within 30 days thereafter as may be agreed upon by Company
and McKesson (the "Initial Warrant Issue Date"). The issuance of the third
installment of Warrants under clause (iii) of Section 3, if any, shall occur on
the tenth day after the date of the Approval Notice or on such other Business
Day within 30 days thereafter as may be agreed upon by the Company and McKesson
(the "Second Warrant Issue Date" and together with the Initial Warrant Issue
Date, the "Warrant Issue Dates"). On each Warrant Issue Date, Company will
deliver to McKesson the relevant Warrants, the Warrants to be in the form of a
single Warrant (or such greater number of Warrants as McKesson may request)
registered in McKesson's name (or in the name of its nominee). If on a Warrant
Issue Date Company shall fail to deliver to McKesson such documents as provided
in the Credit Agreement or Company shall fail to tender to McKesson the Warrants
as provided above in this SECTION 5, or any of the conditions specified in
SECTION 5 shall not have been fulfilled to its satisfaction, McKesson shall, at
its election, be relieved of all further obligations under this Agreement and
the Credit

                                       4.
<PAGE>

Agreement, without thereby waiving any rights McKesson may have by reason of
such failure or such nonfulfillment.

SECTION 6. REPRESENTATIONS AND WARRANTIES.

         SECTION 6.1 PURCHASE FOR INVESTMENT. McKesson represents that it is
purchasing the Warrants for its own account and not with a view to the
distribution thereof, provided that the disposition of its property shall at all
times be within its control. McKesson further represents that it is an
accredited investor within the meaning of Rule 501(a) promulgated under the
Securities Act. McKesson understands that the Warrants have not been registered
under the Securities Act and may be resold only if registered pursuant to the
provisions of the Securities Act or if an exemption from registration is
available, except under circumstances where neither such registration nor such
an exemption is required by law, and that Company is not required to register
the Warrants.

         SECTION 6.2 SOURCE OF FUNDS. McKesson represents that the source of
funds to be used by it to pay the purchase price of the Warrants does not
include assets of any employee benefit plan. As used in this SECTION 6.2, the
term "employee benefit plan" shall have the meaning assigned to such term in
Section 3 of ERISA.

SECTION 7. TRANSFER; REGISTRATION RIGHTS.

         SECTION 7.1 RESTRICTIONS ON TRANSFERABILITY. The Warrants and the
Restricted Shares shall not be transferable except upon the conditions
hereinafter specified, which conditions are intended to ensure compliance with
the provisions of the Securities Act and any applicable state securities laws.

                           1. TRANSFER OF RIGHTS. Subject to SECTION 7.10, the
rights granted to McKesson under this SECTION 7 may be transferred to any person
or entity acquiring directly or indirectly any shares of Warrants or Restricted
Shares, as the case may be, from McKesson.

                           2. TRANSFEREES. Any transferee to whom rights under
SECTION 7 are transferred shall, as a condition to such transfer, agree to be
bound by the obligations imposed by SECTION 7 to the same extent as such
transferee's transferor was bound hereunder.

                           3. SUBSEQUENT TRANSFEREES. A transferee to whom
rights are transferred pursuant to this Section 7 may only transfer such rights
to another person or entity as provided in (a) and (b) of this Section 7.

         SECTION 7.2 NOTICE OF PROPOSED TRANSFER; REGISTRATION NOT REQUIRED. The
Holder of each Warrant or any Restricted Shares, by acceptance thereof, agrees
to give prior written notice to Company of such Holder's intention to transfer
such Warrant (or the Underlying Shares relating thereto) or such Restricted
Shares (or, in each case, any portion thereof), describing briefly the manner
and circumstances of the proposed transfer; provided, however, that no such
notice shall be required for a transfer under a registration requested in
accordance with the provisions of Section 7.3 or in connection with a transfer
made in accordance with the exemptions afforded by Rule 144 or Rule 144A of the
General Rules and Regulations of the Commission (or any other available
exemption from the registration requirements of the

                                       5.
<PAGE>

Securities Act) and exempt from all applicable registration requirements under
state securities laws.

         SECTION 7.3 REQUIRED REGISTRATION (a) On (and including) or after the
twenty-fifth day after the First Anniversary, the Holders of at least 30% of the
aggregate then outstanding number of Underlying Shares and Restricted Shares
may, upon written request, require Company to effect the registration (a "DEMAND
REGISTRATION") or qualification under applicable federal or state securities
laws of such Underlying Shares and/or Restricted Shares. Upon receipt of such
written request, Company shall promptly give written notice to all Holders of
Warrants and Restricted Shares of a proposed registration or qualification, and
shall, subject to the conditions of SECTION 7.4, as expeditiously as possible,
use its best efforts to effect any such registration or qualification of:

                  (i) such Underlying Shares or such Restricted Shares, or any
         combination thereof; or

                  (ii) all other Underlying Shares and Restricted Shares of
         Holders of Warrants or Restricted Shares which shall have advised
         Company in writing within 30 days after the giving of such written
         notice by Company of their desire to have their Underlying Shares or
         Restricted Shares registered or qualified or exempted,

with, or notification to or approval of, any governmental authority under any
federal or state securities laws, or listing with any securities exchange, which
may be required to permit the sale or other disposition of any such Underlying
Shares or Restricted Shares which the Holders thereof propose to make, and
Company will keep effective such registration, qualification, exemption,
notification or approval for such period as may be necessary to effect such
sales or dispositions up to a maximum period of nine months after initial
effectiveness.

         If the managing underwriter engaged in connection with an underwritten
public offering of such Underlying Shares or Restricted Shares proposed for
registration under this SECTION 7.3 determines in good faith and for valid
business reasons that registration of such Underlying Shares or Restricted
Shares would have an adverse effect on the marketability or the price of such
offering (a "CUTBACK DETERMINATION"), such managing underwriter shall give
prompt written notice of such Cutback Determination to such requesting Holder or
Holders. In such event, Company, upon written notice to the Holders of such
Underlying Shares or Restricted Shares, shall have the right to limit such
Underlying Shares or such Restricted Shares to be registered, if any, to the
largest number which would not result in such adverse effect on marketability or
the price of such offering (such limitation being applied to each such
requesting Holder of Underlying Shares or Restricted Shares pro rata in respect
of the number of shares subject to such request). No Securities of any Person,
other than Securities of a Holder or Securities subject to a Permitted
Incidental Registration, may be included in any registration pursuant to this
SECTION 7.3 without the written consent of the Holders of at least a majority of
the Underlying Shares and/or Restricted Shares participating in such offering
if, with the inclusion of such Securities, the Holders are not able to include
in the registration at least 80% of the Underlying Shares and/or Restricted
Shares that they initially requested to be included.

                                       6.
<PAGE>

         (b) REGISTRATION PROCEDURES. In connection with Company's obligations
with respect to a Demand Registration pursuant to SECTION 7.3(a) hereof, Company
shall use its best efforts to effect or cause the registration or qualification
of the Underlying Shares and/or Restricted Shares under the Securities Act and
applicable state securities laws to permit the sale of such Underlying Shares
and/or Restricted Shares by the Holders thereof in accordance with the intended
method of distribution thereof (if such distribution is possible), and pursuant
thereto, Company shall:

                  (i) prepare and, within 60 days after receipt of the request
         pursuant to SECTION 7.3(a) hereof, file with the Commission a
         registration statement or registration statements with respect to a
         Demand Registration on any form which may be utilized by Company and
         which shall permit the disposition of the Underlying Shares and/or
         Restricted Shares in accordance with the intended method or methods
         thereof, and use its best efforts to cause such registration statement
         or registration statements to become effective as expeditiously as
         possible, but in any event not later than 120 days after receipt of
         such request;

                  (ii) prepare and file with the Commission such amendments and
         supplements to a registration statement or statements hereunder and the
         prospectus used in connection therewith as may be necessary to maintain
         the effectiveness of such registration statement for the applicable
         period specified in SECTION 7.3(a) hereof, and comply in all material
         respects with the provisions of the Securities Act and applicable state
         securities laws with respect to the disposition of all of the
         Underlying Shares and/or Restricted Shares to be included in such
         registration statement during such applicable period in accordance with
         the intended methods of disposition by the Holders thereof set forth in
         the registration statement;

                  (iii) provide the Holders of the Underlying Shares and/or
         Restricted Shares to be included in a registration statement hereunder
         and the underwriters (which term, for purposes of this Agreement, shall
         include a Person deemed to be an underwriter within the meaning of
         Section 2(11) of the Securities Act), if any, of the Securities being
         sold and counsel for such underwriters and not more than one counsel
         for such Holders the opportunity to participate in the preparation of
         such registration statement, each prospectus included therein or filed
         with the Commission, and each amendment or supplement thereto; and make
         available for inspection by such Persons such financial and other
         information, books and records of Company, and cause the officers,
         directors and employees of Company, and counsel and independent
         certified public accountants for Company, to respond to such inquiries,
         as shall be reasonably necessary, in the opinion of the respective
         counsel to such Holders and such underwriters, to conduct a reasonable
         investigation within the meaning of the Securities Act;

                  (iv) promptly notify the selling Holders of Underlying Shares
         and/or Restricted Shares to be included in a registration statement
         hereunder and the managing underwriters, if any, of the Securities
         being sold and (if requested by any such Person) confirm such advice in
         writing, (1) when such registration statement, the prospectus or any
         prospectus supplement or post-effective amendment has been filed, and,
         with respect to such registration statement or any post-effective
         amendment, when the same has

                                       7.
<PAGE>

         become effective, (2) of any request by the Commission for amendments
         or supplements to such registration statement or the prospectus or for
         additional or supplemental information, (3) of the issuance by the
         Commission of any stop order suspending the effectiveness of such
         registration statement or the initiation of any proceedings for that
         purpose, (4) if at any time the representations and warranties of
         Company contemplated by paragraph (xi) below cease to be true and
         correct in all material respects, (5) of the receipt by Company of any
         notification with respect to the suspension of the qualification of the
         Underlying Shares or Restricted Shares for sale in any jurisdiction or
         the initiation or threat of any proceeding for such purpose, or (6) at
         any time when a prospectus is required to be delivered under the
         Securities Act, of the happening of any event as a result of which such
         registration statement, prospectus, any prospectus supplement, or any
         document incorporated by reference in any of the foregoing contains an
         untrue statement of a material fact or omits to state any material fact
         required to be stated therein or necessary to make the statements
         therein not misleading in light of the circumstances then existing;

                  (v) make reasonable efforts to obtain the withdrawal of any
         order suspending the effectiveness of a registration statement
         hereunder or any post-effective amendment thereto at the earliest
         practicable date;

                  (vi) if requested by the managing underwriter or underwriters
         or the Holders of at least a majority of the Underlying Shares and/or
         Restricted Shares being sold, promptly incorporate in a prospectus
         supplement or post-effective amendment such information as such
         managing underwriter or underwriters or such Holders of at least a
         majority of the Underlying Shares and/or Restricted Shares being sold
         specify should be included therein relating to the sale of the
         Underlying Shares and/or Restricted Shares, including, without
         limitation, information with respect to the number of Underlying Shares
         and/or Restricted Shares being sold to such underwriters, the purchase
         price being paid therefor by such underwriters and with respect to any
         other terms of the underwritten (or best efforts underwritten) offering
         of the Underlying Shares and/or Restricted Shares to be sold in such
         offering, except to the extent that Company is advised in a written
         opinion of outside counsel that the inclusion of such information is
         reasonably likely to violate the federal securities laws; and make all
         required filings of such prospectus supplement or post-effective
         amendment promptly after notification of the matters to be incorporated
         in such prospectus supplement or post-effective amendment;

                  (vii) furnish to each Holder of Underlying Shares and/or
         Restricted Shares to be included in a registration statement hereunder
         and each underwriter, if any, of the Securities being sold such number
         of copies of such registration statement, each such amendment and
         supplement thereto (in each case including all exhibits thereto), the
         prospectus included in such registration statement and such other
         documents as such Holder and underwriter, if any, may reasonably
         request in order to facilitate the disposition of the Underlying Shares
         and/or Restricted Shares owned by such Holder; Company consents to the
         use of the prospectus or any amendment or supplement thereto by each of
         the selling Holders of Underlying Shares and/or Restricted Shares and
         the underwriters in connection with the offering and sale of the
         Underlying Shares and/or Restricted Shares covered by the prospectus or
         any supplement or amendment thereto;

                                       8.
<PAGE>

                  (viii) use its best efforts to (1) register or qualify the
         Underlying Shares and/or Restricted Shares to be included in a
         registration statement hereunder under such other securities laws or
         Blue Sky laws of such jurisdictions as any Holder of such Underlying
         Shares and/or Restricted Shares and each underwriter, if any, of the
         Securities being sold shall reasonably request, (2) keep such
         registrations or qualifications in effect for so long as the
         registration statement remains in effect and (3) take any and all such
         actions as may be reasonably necessary or advisable to enable such
         Holder and underwriter, if any, to consummate the disposition in such
         jurisdictions of such Underlying Shares and/or Restricted Shares owned
         by such Holder; PROVIDED, HOWEVER, that Company shall not be required
         for any such purpose to (A) qualify generally to do business as a
         foreign corporation in any jurisdiction wherein it would not otherwise
         be required to qualify but for the requirements of this paragraph
         (viii) or (B) consent to general service of process in any such
         jurisdiction;

                  (ix) use its best efforts to cause all of the Underlying
         Shares and/or Restricted Shares that are to be included in a
         registration statement hereunder to be registered with or approved by
         such other governmental agencies or authorities as may be necessary by
         virtue of the business and operations of Company to enable the Holder
         or Holders thereof to consummate the disposition of such Underlying
         Shares and/or Restricted Shares;

                  (x) use its best efforts in cooperation with the Holders of
         the Underlying Shares and/or Restricted Shares to be included in a
         registration statement hereunder and the managing underwriters, if any,
         to facilitate the timely preparation and delivery of certificates
         representing Underlying Shares and/or Restricted Shares to be sold and
         not bearing any restrictive legends; and, in the case of an
         underwritten offering, enable such Underlying Shares and/or Restricted
         Shares to be in such denominations and registered in such names as the
         managing underwriters may request at least two Business Days prior to
         any sale of the Underlying Shares and/or Restricted Shares;

                  (xi) enter into such customary agreements (including an
         underwriting agreement, in the event that the shares to be included are
         to be distributed by means of an underwritten public offering) and take
         such other actions in connection therewith as the Holders of at least a
         majority of the Underlying Shares and/or Restricted Shares to be
         included in a registration statement hereunder shall reasonably request
         in order to expedite or facilitate the disposition of such Underlying
         Shares and/or Restricted Shares and in such connection, whether or not
         an underwriting agreement is entered into and whether or not the
         disposition is an underwritten offering, (1) make such representations,
         warranties and indemnities to the Holders of such Underlying Shares
         and/or Restricted Shares and the underwriters, if any, in form,
         substance and scope as are customarily made in an underwritten
         offering; (2) obtain an opinion of counsel to Company in customary form
         and covering such matters of the type customarily covered by such
         opinion as the Holders of at least a majority of the Underlying Shares
         and/or Restricted Shares to be included in such registration statement
         and the underwriters, if any, may reasonably request, addressed to the
         selling Holders and the underwriters, if any, and dated the effective
         date of such registration statement and dated the effective date of a
         post-effective amendment to the registration statement, if such is
         filed (or, if such registration statement covers an underwritten
         offering, dated the date of the closing as specified in the

                                       9.
<PAGE>

         underwriting agreement); (3) obtain a "cold comfort" or procedures
         letter from the independent certified public accountants of Company
         addressed to the selling Holders of Underlying Shares and/or Restricted
         Shares and to the underwriters, if any, dated the effective date of
         such registration statement and dated the effective date of a
         post-effective amendment to the registration statement, if such is
         filed (and, if such registration statement covers an underwritten
         offering, dated the date of the closing as specified in the
         underwriting agreement), such letter to be in customary form and
         covering such matters of the type customarily covered by such letter;
         and (4) deliver such documents and certificates as may be reasonably
         requested by the Holders of at least a majority of the Underlying
         Shares and/or Restricted Shares being sold and the managing
         underwriters, if any, to evidence compliance with clause (1) above and
         with any customary conditions contained in the underwriting agreement
         or other agreement entered into by Company;

                  (xii) otherwise use its best efforts to comply with all
         applicable rules and regulations of the Commission, and make available
         to its security holders, as soon as reasonably practicable, an earnings
         statement covering a period of at least twelve months which shall
         satisfy the provisions of Section 11(a) of the Securities Act and Rule
         158 of the Commission thereunder;

                  (xiii) provide a transfer agent and registrar for all
         Underlying Shares and/or Restricted Shares registered pursuant to such
         registration statement and a CUSIP number for all such Underlying
         Shares and/or Restricted Shares, in each case not later than the
         effective date of such registration; and

                  (xiv) use its best efforts to have the Underlying Shares
         and/or Restricted Shares listed, subject to notice, on the American
         Stock Exchange or other applicable national securities exchange as
         Company shall determine to be appropriate.

         Upon the occurrence of any event contemplated by paragraph (iv) above,
Company shall, as soon as reasonably practicable, prepare and furnish to each
Holder included in such registration statement and underwriter, if any, a
reasonable number of copies of a prospectus supplemented or amended so that, as
thereafter delivered to the purchasers of the Underlying Shares and/or
Restricted Shares, such prospectus shall not contain an untrue statement of a
material fact or omit to state a material fact required to be stated therein or
necessary to make the statements therein not misleading in light of the
circumstances then existing. Each Holder of Underlying Shares and/or Restricted
Shares agrees that upon receipt of any notice from Company of the happening of
any event of the kind described in paragraph (iv) hereof, such Holder shall
forthwith discontinue the disposition of Underlying Shares and/or Restricted
Shares pursuant to the registration statement applicable to such Underlying
Shares and/or Restricted Shares until such Holder receives copies of such
amended or supplemented registration statement or prospectus, and, if so
directed by Company, such Holder shall deliver to Company (at Company's expense)
all copies, other than permanent file copies, then in such Holder's possession
of the prospectus covering such Underlying Shares and/or Restricted Shares at
the time of receipt of such notice.

                                      10.
<PAGE>

         Company may require each Holder of Underlying Shares and/or Restricted
Shares as to which any registration is being effected to furnish to Company such
information regarding such Holder and the distribution of such Underlying Shares
and/or Restricted Shares as Company may from time to time reasonably request in
writing in order to comply with the Securities Act. Each Holder of Underlying
Shares and/or Restricted Shares as to which any registration is being effected
agrees to notify Company as promptly as practicable of any inaccuracy or change
in information previously furnished by such Holder to Company or of the
happening of any event, in either case as a result of which any prospectus
relating to such registration contains an untrue statement of a material fact
regarding such Holder or the distribution of such Underlying Shares and/or
Restricted Shares or omits to state any material fact regarding such Holder or
the distribution of such Underlying Shares and/or Restricted Shares required to
be stated therein or necessary to make the statements therein not misleading in
light of the circumstances then existing, and to furnish promptly to Company any
additional information required to correct and update any previously furnished
information or required so that such prospectus shall not contain, with respect
to such Holder or the intended method of distribution of such Underlying Shares
and/or Restricted Shares, an untrue statement of a material fact or omit to
state a material fact required to be stated therein or necessary to make the
statements therein not misleading in light of the circumstances then existing.

         SECTION 7.4 CONDITIONS TO REQUIRED REGISTRATION. Company shall not be
required to register or effect any registration or qualification of Underlying
Shares and/or Restricted Shares pursuant to SECTION 7.3:

                  (a) more than one (1) time, PROVIDED that no registration
         shall be included as a required registration pursuant to this SECTION
         7.4(a) until such time, if any, as the registration statement filed in
         connection therewith shall be declared effective and remain effective
         until such time as all Shares (and Underlying Shares, as applicable)
         have been sold under such registration statement or may be freely sold
         in the public market without registration in reliance upon Rule 144(k)
         and unless the Holders requesting such registration are able to include
         in such registration all of the Underlying Shares and/or Restricted
         Shares that they initially requested to be included;

                  (b) unless there shall have elapsed after a previous
         registration of Underlying Shares and/or Restricted Shares pursuant to
         SECTION 7.3 or a registration of other shares in which the Holders of
         the Underlying Shares or Restricted Shares could participate pursuant
         to SECTION 7.5 a period of 90 days or such longer period, not to exceed
         180 days, as the managing underwriter in any such registration shall
         have determined to be necessary or desirable in light of then current
         market conditions; and

                  (c) unless the request therefor is to register not less than
         30% of the aggregate number of Underlying Shares and Restricted Shares
         not theretofore registered pursuant to Section 7.3 or Section 7.5.

         SECTION 7.5 INCIDENTAL REGISTRATIONS. Company agrees that at any time
it proposes to register any of its Securities in a primary or secondary offering
of such Securities under the Securities Act (otherwise than pursuant to SECTION
7.3) on Form S-1 or any other form of registration statement (other than Form
S-4 or Form S-8) then available for the registration under

                                      11.
<PAGE>

the Securities Act of Securities of Company, it will give timely written notice
to all Holders of outstanding Warrants and Restricted Shares of its intention so
to do and upon the written request of the Holder of any such Warrants or
Restricted Shares, given within 30 days after receipt of any such notice from
Company, Company will in each instance, subject to the next paragraph of this
SECTION 7.5, use its best efforts to cause all Underlying Shares or Restricted
Shares requested to be included in such registration by any such requesting
Holder to be registered under the Securities Act and registered or qualified
under any state securities laws, all to the extent necessary to permit the sale
or other disposition thereof in the manner stated in such request by the
prospective seller of the Securities so registered. Nothing in this SECTION 7.5
shall be deemed to require Company to proceed with any registration of its
Securities after giving the notice herein provided. Registration pursuant to
this SECTION 7.5 shall be in accordance with, and subject to the provisions of,
the "Registration Procedures" set forth in SECTION 7.3(b).

         If the managing underwriter engaged by Company in connection with an
underwritten public offering of Securities proposed for registration as
described in this Section 7.5 determines in good faith and for valid business
reasons that registration of the Underlying Shares or Restricted Shares proposed
for inclusion in such registration would, when combined with the other
Securities to be included in such registration, have an adverse effect on the
marketability or the price of such offering (an "Incidental Cutback
Determination"), such managing underwriter shall give prompt written notice of
such Incidental Cutback Determination to such requesting Holder or Holders. In
such event Company, upon written notice to the Holders of such Underlying Shares
or Restricted Shares, shall have the right to limit such Underlying Shares or
such Restricted Shares and such other Securities to be registered, if any, to
the largest number which would not result in such adverse effect on
marketability or the price of such offering (such limitation being applied to
each such requesting Holder of Underlying Shares or Restricted Shares and holder
of such other Securities pro rata in respect of the number of shares subject to
such request).

         SECTION 7.6 UNDERWRITTEN OFFERINGS. If the intended method of
distributing the Underlying Shares and/or Restricted Shares to be included in a
registration pursuant to Section 7.3 or Section 7.5 is an underwritten public
offering, then Company shall select the managing underwriter(s) for such
offering, subject to the written consent of the Holders of at least 51% of the
Underlying Shares and/or Restricted Shares to be included in such registration,
which consent shall not be unreasonably withheld. Each Holder of said Underlying
Shares and/or Restricted Shares shall enter into an underwriting agreement,
custody agreement and power of attorney in such forms as the managing
underwriter(s) and Company shall reasonably request, provided that such
agreements and documents are in customary form and substance or reasonably
acceptable to the Holders of a majority of said Underlying Shares and/or
Restricted Shares. Each Holder of the Warrants or Restricted Shares shall
refrain from selling Warrants or Restricted Shares for a period not to exceed 90
days from the date of the public offering of any Underlying Shares or Restricted
Shares which are not included in registration pursuant to Section 7.3 or Section
7.5.

         SECTION 7.7 EXPENSES; RELIANCE. Company will pay all expenses,
including, without limitation, registration fees, qualification fees, legal
expenses (including the reasonable fees and expenses of one counsel to the
Holders of Warrants or Restricted Shares whose Underlying Shares or Restricted
Shares are being registered), printing expenses and the costs of special

                                      12.
<PAGE>

audits, if any, and "cold comfort" letters, expenses of underwriters (excluding
underwriting discounts and commissions, but including the reasonable fees and
expenses of any necessary special experts) in connection with the registration
and qualification, notification or exemption requested by any Holder or Holders
of Warrants or Restricted Shares pursuant to Section 7.3 or Section 7.5. The
Holders of the Underlying Shares and/or Restricted Shares shall be responsible
for applicable transfer taxes, brokerage commissions and their share of the
underwriting discounts and commissions.

         SECTION 7.8 INDEMNIFICATION AND CONTRIBUTIO (a) In connection with any
registration, qualification, notification, or exemption of Securities under
SECTION 7.3 or SECTION 7.5, Company hereby indemnifies each Holder of the
Warrants, Underlying Shares and/or Restricted Shares, including each Person, if
any, who controls each such Holder within the meaning of Section 15 of the
Securities Act, against all losses, claims, damages and liabilities (including,
without limitation, any liability of any such Holder or Person to any
underwriter participating in any such registration, qualification, notification
or exemption) caused by any untrue, or alleged untrue, statement of a material
fact contained in any registration statement or prospectus or notification or
offering circular (and as amended or supplemented if Company shall have
furnished any amendments or supplements thereto) or any preliminary prospectus
or caused by any omission or alleged omission to state therein a material fact
required to be stated therein or necessary to make the statements therein not
misleading, except insofar as such losses, claims, damages or liabilities are
caused by any untrue statement or alleged untrue statement or omission or
alleged omission based upon information furnished in writing to Company by such
Holder expressly for use therein, and Company and each officer, director and
controlling Person of Company shall be indemnified by each Holder of the
Underlying Shares and/or Restricted Shares for all such losses, claims, damages
and liabilities caused by any untrue statement or alleged untrue statement or
omission or alleged omission based upon information furnished in writing to
Company by each such Holder thereof expressly for any such use. The foregoing is
subject to the condition that, insofar as it relates to any untrue statement,
alleged untrue statement or omission or alleged omission made in any preliminary
prospectus but eliminated or remedied in the final prospectus (or in any
amendment or supplement thereto), the indemnity of Company shall not inure to
the benefit of any underwriter from whom the Person asserting any loss, claim or
damage purchased the Underlying Shares and/or Restricted Shares which were the
subject thereof (or to the benefit of any Person who controls such underwriter),
if a copy of the final prospectus (or such amendment or supplement thereto) was
not sent or given to such Person at or prior to the time such action is required
by the Securities Act.

         (b) Promptly upon receipt by a party indemnified under this SECTION 7.8
of notice of the commencement of any action against such indemnified party in
respect of which indemnity or reimbursement may be sought against any
indemnifying party under this SECTION 7.8, such indemnified party shall notify
the indemnifying party in writing of the commencement of such action, but the
failure so to notify the indemnifying party shall not relieve it of any
liability which it may have to any indemnified party (i) under this SECTION 7.8
except to the extent that the indemnifying party is materially prejudiced by
such failure to notify, or (ii) otherwise than under this SECTION 7.8. In case
notice of commencement of any such action shall be given to the indemnifying
party as above provided, the indemnifying party shall be entitled to participate
in and, to the extent it may wish, jointly with any other indemnifying party
similarly notified, to assume the defense of such action at its own expense,
with counsel chosen by it and satisfactory

                                      13.
<PAGE>

to such indemnified party. The indemnified party shall have the right to employ
separate counsel in any such action and participate in the defense thereof, and
the fees and expenses of such counsel (other than reasonable costs of
investigation) shall be paid by the indemnifying party unless the indemnified
party agrees to pay the same. No indemnifying party shall be liable for any
settlement entered into without its consent. In addition to its other
obligations under this SECTION 7.8, each indemnifying party agrees that, as an
interim measure during the pendency of any claim, action, investigation, inquiry
or other proceeding arising out of or based upon any statement or omission, or
any alleged statement or omission, described in this SECTION 7.8, it will
reimburse each indemnified party on a monthly basis for all reasonable legal and
other expenses incurred in connection with investigating or defending any such
claim, action, investigation, inquiry or other proceeding, notwithstanding the
absence of a judicial determination as to the propriety and enforceability of
the indemnifying party's obligation to reimburse the indemnified party or
parties for such expenses and the possibility that such payments might later be
held to have been improper by a court of competent jurisdiction.

         (c) If the indemnification provided for in this SECTION 7.8 from the
indemnifying party is unavailable to an indemnified party hereunder in respect
of any losses, claims, damages, liabilities or expenses to which such
indemnified party would be otherwise entitled under SECTION 7.8(a), then the
indemnifying party, in lieu of indemnifying such indemnified party, shall
contribute to the amount paid or payable by such indemnified party as a result
of such losses, claims, damages, liabilities or expenses in such proportion as
is appropriate to reflect the relative fault of the indemnifying party and
indemnified parties in connection with the actions which resulted in such
losses, claims, damages, liabilities or expenses, as well as any other relevant
equitable considerations. The relative fault of such indemnifying party and
indemnified parties shall be determined by reference to, among other things,
whether any action in question, including any untrue or alleged untrue statement
of a material fact or omission or alleged omission to state a material fact, has
been made by, or relates to information supplied by, such indemnifying party or
indemnified parties, and the parties' relative intent, knowledge, access to
information and opportunity to correct or prevent such action. The amount paid
or payable by a party as a result of the losses, claims, damages, liabilities
and expenses referred to above shall be deemed to include any legal or other
fees or expenses reasonably incurred by such party in connection with any
investigation or proceeding. In no event shall any Holder of Warrants,
Underlying Shares or Restricted Shares be required to contribute an amount
greater than the dollar amount of the proceeds received by such Person with
respect to the sale of any Warrants, Underlying Shares or Restricted Shares.

         The parties hereto agree that it would not be just and equitable if
contribution pursuant to this SECTION 7.8(c) were determined by PRO RATA
allocation or by any other method of allocation which does not take account of
the equitable considerations referred to in the immediately preceding paragraph.
No Person guilty of fraudulent misrepresentation (within the meaning of Section
11(f) of the Securities Act) shall be entitled to contribution from any Person
who was not guilty of such fraudulent misrepresentation.

         (d) The indemnification and contribution provided for in this SECTION
7.8 shall survive, with respect to a Holder of Underlying Shares of Restricted
Shares, the transfer of Underlying Shares or Restricted Shares by such Holder
and with respect to a Holder of

                                      14.
<PAGE>

Underlying Shares or Restricted Shares, shall remain in full force and effect
regardless of any investigation made by or on behalf of any indemnified party.

         (e) In connection with any registration pursuant to Section 7.3 or
Section 7.5, Company agrees, and each Holder of Warrants or Restricted Shares
(except for McKesson and any other than any such Holder which shall have
executed and delivered a counterpart of this Agreement) by acceptance of such
Warrants, or Restricted Shares, agrees that it will enter into an agreement
containing substantially the indemnification provisions of this Section 7.8.

         SECTION 7.9 ADDITIONAL REGISTRATION RIGHTS. Company will not grant to
any Person at any time after the date hereof the right to request Company to
effect the registration or qualification or filing for exemption under
applicable federal or state securities laws of any Securities of Company, unless
the agreement or agreements providing for such rights specifically provide that
the holders of such rights may not participate in any registration requested
pursuant to Section 7.3 if such participation would violate the last sentence of
Section 7.3(a).

         SECTION 7.10 RESTRICTIVE LEGENDS. Each Warrant initially issued and
each Warrant issued in exchange therefor shall, unless otherwise permitted by
the provisions of this SECTION 7.10, bear on the face thereof a legend reading
substantially as follows:

                  This Warrant and the shares of Common Stock issuable upon
                  exercise hereof have not been registered or qualified for sale
                  under the Securities Act of 1933, as amended, or any state
                  securities laws and may not be offered for sale, sold or
                  otherwise transferred unless such offer, sale or transfer is
                  registered or qualified pursuant to the registration
                  requirements of such Securities Act and any applicable state
                  securities laws, or is preceded by an opinion of counsel
                  addressed to HORIZON Pharmacies, Inc. that such sale or other
                  transfer is exempt from all such registration requirements.
                  This Warrant and the shares of Common Stock issuable upon
                  exercise hereof are subject to the terms and provisions
                  specified in the Amended and Restated Warrant Purchase
                  Agreement dated as of May 14, 1999, between HORIZON
                  Pharmacies, Inc., and McKesson HBOC, Inc.

         Each certificate for shares of Common Stock of Company initially issued
upon the exercise of any Warrant and each certificate for shares of Common Stock
of Company issued to a subsequent transferee of such certificate shall, unless
otherwise permitted by the provisions of this SECTION 7.10, bear on the face
thereof a legend reading substantially as follows:

                  The shares represented by this certificate have not been
                  registered under the Securities Act of 1933, as amended, or
                  any state securities laws and may not be sold or transferred
                  in the absence of such registration unless such sale or
                  transfer is preceded by an opinion of counsel addressed to
                  HORIZON Pharmacies, Inc., that such sale or other transfer is
                  exempt from the registration requirements of said Securities
                  Act and any such state securities

                                      15.
<PAGE>

                  laws which may be applicable and are subject to of the terms
                  and provisions specified in that certain Amended and Restated
                  Warrant Purchase Agreement dated as of May 14, 1999, between
                  HORIZON Pharmacies, Inc., and McKesson HBOC, Inc.

         In the event that a registration statement covering Underlying Shares
or Restricted Shares shall become effective under the Securities Act and under
any applicable state securities laws or in the event that Company shall receive
an opinion of its counsel (or, at Company's election, nationally recognized
independent counsel to any Holder) that, in the opinion of such counsel, such
legend is not, or is no longer, necessary or required (including, without
limitation, because of the availability of the exemptions afforded by Rule 144
or Rule 144A of the General Rules and Regulations of the Commission), Company
shall, or shall instruct its transfer agents and registrars to, remove such
legend from the Warrants and certificates evidencing Restricted Shares or issue
new Warrants and certificates without such legend in lieu thereof. Upon the
written request of the Holder or Holders of any Warrants or any Restricted
Shares, Company covenants and agrees forthwith to request its counsel to render
an opinion with respect to the matters covered by this Section 7.10 and any
legends set forth on the Warrants and Restricted Share certificates and to bear
all reasonable expenses in connection with any opinion of counsel contemplated
hereinabove.

         SECTION 7.11 STOCK EXCHANGE LISTING. In the event Company's Common
Stock is listed on a national securities exchange at the time of exercise of a
Warrant, Company will, at its expense, also list on such exchange, upon exercise
of the Warrant, all shares of Common Stock issuable pursuant to such Warrant.

         SECTION 7.12 MISCELLANEOUS. Company shall comply with all issuer
reporting requirements set forth or referred to in Rule 144 or Rule 144A
promulgated under the Securities Act and will do all such other things as may be
reasonably necessary to permit the expeditious sale at any time of any Warrants,
Restricted Shares or Underlying Shares by the Holder thereof in accordance with
and to the extent permitted by said Rule 144 or Rule 144A, as the case may be,
or any other similar Rule or Rules promulgated by the Commission from time to
time.

SECTION 8.  REDEMPTION OF WARRANTS.

         Company shall have no right or option exercisable at its election to
redeem or call any Warrant or any Restricted Shares.

SECTION 9.  LOST, STOLEN WARRANTS, ETC.

         In case any Warrant shall be mutilated, lost, stolen or destroyed,
Company may issue a new Warrant of like date, tenor and denomination and deliver
the same in exchange and substitution for and upon surrender and cancellation of
the mutilated Warrant, or in lieu of the lost, stolen or destroyed Warrant, upon
receipt of evidence satisfactory to Company of the loss, theft or destruction of
such Warrant, and upon receipt of indemnity satisfactory to Company (which, in
the case of McKesson, shall consist of its unsecured agreement to indemnify
Company for a loss in connection with such loss, theft or destruction of such
Warrant).

                                      16.
<PAGE>

SECTION 10.  RESTRICTIONS ON CAPITAL STRUCTURE.

         Company will not, without the written consent of the Holders of at
least 75% of the then outstanding Warrants and Restricted Shares (determined on
a Common Stock equivalent basis):

                  (i) be bound by or subject to (or permit Company to be bound
         by or subject to) any debt or other agreement which restricts the right
         or ability of Company to perform its obligations hereunder or under the
         Warrants; or

                  (ii) amend or change the Certificate of Incorporation or
         bylaws (each as currently amended and/or restated) in a manner which
         could materially and adversely affect this Agreement, the Warrants, the
         Restricted Shares or the rights of any Holder of any of the foregoing
         (unless such amendment or change (a) is solely with respect to the
         rights, preferences and privileges of the outstanding capital stock of
         Company and (b) affects all shares of Common Stock equally) or violate
         any of the terms or provisions thereof.

SECTION 11.  INDEX AND CAPTIONS.

         The index and the descriptive headings of the various sections of this
Agreement are for convenience only and shall not affect the meaning or
construction of the provisions hereof.

SECTION 12.  MISCELLANEOUS.

         SECTION 12.1 NOTICES. All notices and communications provided for
hereunder shall be in writing and sent (a) by telecopy if the sender on the same
day sends a confirming copy of such notice by a recognized overnight delivery
service (charges prepaid), or (b) by registered or certified mail with return
receipt requested (postage prepaid), or (c) by a recognized overnight delivery
service (specifying next business day delivery, with charges prepaid). Any such
notice must be sent:

                  (i) if to McKesson or its nominee, to McKesson at the address
         specified for such communications in Schedule A, or at such other
         address as McKesson shall have specified to Company in writing, or

                  (ii) if to Company, at 275 W. Princeton Drive, Princeton,
         Texas 75407, or to such other address as Company may designate to the
         Holders in writing.

Notices under this Section 12.1 will be deemed given only when actually
received.

         SECTION 12.2 SUCCESSORS AND ASSIGNS. This Agreement shall be binding
upon Company and its respective successors and assigns and shall inure to the
benefit of McKesson and its successors and permitted assigns, including each
successive Holder.

         SECTION 12.3 SEVERABILITY. Should any part of this Agreement for any
reason be declared invalid or unenforceable, such decision will not affect the
validity or enforceability of any remaining portion, which remaining portion
will remain in force and effect as if this Agreement had been executed with the
invalid or unenforceable portion thereof eliminated and it

                                      17.
<PAGE>

is hereby declared the intention of the parties hereto that they would have
executed the remaining portion of this Agreement without including therein any
such part or portion which may, for any reason, be hereafter declared invalid or
unenforceable.

         SECTION 12.4 GOVERNING LAW. This Agreement shall be construed and
enforced in accordance with, and the rights of the parties shall be governed by,
the law of the State of California, excluding choice-of-law principles of the
law of such state that would require the application of the laws of a
jurisdiction other than such state.

         SECTION 12.5 AMENDMENTS. This Agreement may be amended only by an
instrument in writing executed by the Holders of the Warrants and Restricted
Shares then outstanding and Company.

         The execution hereof by the undersigned shall constitute a contract
between Company and McKesson for the uses and purposes hereinabove set forth.
This Agreement may be executed in any number of counterparts, each executed
counterpart constituting an original but all together only one agreement.

                                                HORIZON PHARMACIES, INC.

                                                By /s/ John N. Stogner
                                                  ------------------------------
                                                    Its CFO/Treasurer
                                                       -------------------------

Accepted and agreed to as of May 14, 1999.

                                                McKESSON HBOC, INC.

                                                By /s/ Alan Pearce
                                                  ------------------------------
                                                    Name Alan Pearce
                                                    Title Senior Vice President
                                                          Financial Services

                                      18.
<PAGE>

                                   SCHEDULE A
                             (TO WARRANT AGREEMENT)

                         NOTICE AND PAYMENT INSTRUCTIONS

Notices:              McKesson HBOC, Inc.
                      One Post Street, 28th Floor
                      San Francisco, California 94104
                      Facsimile No.:  (415) 983-8464
                      Attention:  Assistant Treasurer

with a copy to:       McKesson HBOC, Inc.
                      One Post Street, 29th Floor
                      San Francisco, California 94104
                      Facsimile No.:  (415) 983-9369
                      Attention:  Legal Department

Payment:              McKesson HBOC, Inc.
                      Account No.: 12337-53022
                      Bank of America, N.T.&S.A.
                      ABA No.: 121000358

                                   19.<PAGE>

                    FIRST AMENDMENT TO AMENDED AND RESTATED
                           WARRANT PURCHASE AGREEMENT

                  This First Amendment to Amended and Restated Warrant Purchase
Agreement (this "Amendment") is entered into as of March 30, 2000, between
HORIZON Pharmacies, Inc., a Delaware corporation ("Company") and McKesson HBOC,
Inc., a Delaware corporation formerly known as McKesson Corporation
("McKesson").

                                    RECITALS

                  WHEREAS, Company and McKesson are parties to that certain
Amended and Restated Warrant Purchase Agreement dated as of May 14, 1999 (the
"Warrant Purchase Agreement"). Capitalized terms used herein without definition
shall have the same meanings herein as ascribed thereto pursuant to the Warrant
Purchase Agreement.

                  WHEREAS, Company has requested that McKesson grant Company
certain waivers and consents with respect to matters in the Credit Agreement and
the Warrant Purchase Agreement, and McKesson is willing to do so upon certain
terms and conditions, including but not limited to certain amendments being made
in the Warrant Purchase Agreement and an additional Warrant being issued to
McKesson.

                  NOW, THEREFORE, in consideration of the promises and
agreements, provisions and covenants herein contained, and McKesson's concurrent
waiver and consent as to certain matters under the Credit Agreement, the parties
hereto agree as follows:

SECTION 1.        THE ISSUANCE OF NEW WARRANT; AMENDMENTS TO WARRANT PURCHASE
                  AGREEMENT AND WARRANTS.

         A. The Company hereby agrees to issue a new Warrant under the Warrant
Purchase Agreement (as amended pursuant hereto) for 10,000 shares of Company's
Common Stock with an exercise price of $5.5625 per share. The date of issuance
of such new Warrant shall be deemed to be the "Third Warrant Issue Date", and
the definition of "Warrant Issue Dates" in Section 5 of the Warrant Purchase
Agreement is hereby amended to mean the Initial Warrant Issue Date, the Second
Warrant Issue Date, and the Third Warrant Issue Date.

         B. Section 3 of the Warrant Purchase Agreement is hereby amended to
read in full as follows:

                  SECTION 3.   SALE AND PURCHASE OF WARRANTS.

                               Subject to the terms and conditions of this
                  Agreement, Company will issue and sell to McKesson, and
                  McKesson will purchase from Company, at the relevant Warrant
                  Issue Date, the following installments of Warrants:

<PAGE>

                                    (i) On the Initial Warrant Issue Date,
                  Warrants for 101,500 shares of Common Stock of Company with an
                  initial Exercise Price of $5.71 in exchange for and upon
                  surrender of the Warrants issued on July 2, 1998;

                                    (ii) On the Initial Warrant Issue Date,
                  additional Warrants for 100,000 shares of Common Stock of
                  Company with an initial Exercise Price of $5.71;

                                    (iii) On the Second Warrant Issue Date,
                  Warrants for 50,000 shares of Common Stock of Company with an
                  Exercise Price equal to the average closing price of Common
                  Stock of Company for the five business day period commencing
                  on the date of the Approval Notice; and

                                    (iv) On the Third Warrant Issue Date,
                  Warrants for 10,000 shares of Common Stock of Company with an
                  Initial Exercise Price of $5.5625.

         The aggregate purchase price for the Warrants described in clauses (i),
         (ii) and (iii) above shall be McKesson's execution and delivery of the
         Credit Agreement. The purchase price for the Warrant described in
         clause (iv) above shall be McKesson's execution and delivery of the
         Limited Waiver and Consent dated the Third Warrant Issue Date.

                  Company and McKesson agree that the per share value of the
         Warrants for tax purposes is $2.55. Company and McKesson agree to
         report the transaction in a manner consistent with this paragraph.

         C. Section 7.4 of the Warrant Purchase Agreement is hereby amended by
substituting in clause (a) thereof the phrase "more than two (2) times" for the
phrase "more than one (1) time".

         D. The form of Exhibit A to the Warrant Purchase Agreement is hereby
amended by inserting the following sentence at the end of Section 3.3 thereof.

                  If the price per share at which any holder of Convertible
                  Securities may purchase Additional Shares of Common Stock is
                  modified because of purchase price adjustments, reset
                  provisions, floating conversion, exercise or exchange prices
                  or otherwise, then the occurrence of any such change shall be
                  deemed to be a reissuance of such Convertible Securities and
                  such reissuance shall be subject to the provisions of this
                  Section 3.3.

Any of the Warrants already issued shall be deemed hereby amended to include
such additional sentence.

                                       2
<PAGE>

SECTION 2.        MISCELLANEOUS

         A. Reference to and Effect on the Warrant Purchase Agreement and the
Other Loan Agreements.

                  (i) On and after the date hereof, each reference in the
Warrant Purchase Agreement to "this Agreement", "hereunder", "hereof", "herein"
or words of like import referring to the Warrant Purchase Agreement, and each
reference in the other Loan Documents to the "Warrant Purchase Agreement",
"thereunder", "thereof" or words of like import referring to the Warrant
Purchase Agreement shall mean and be a reference to the Warrant Purchase
Agreement as amended by this Amendment.

                  (ii) Except as specifically amended by this Amendment, the
Warrant Purchase Agreement, the Warrants and the other Loan Documents shall
remain in full force and effect and are hereby ratified and confirmed.

         B. COSTS AND EXPENSES. The Company covenants to pay to or reimburse
McKesson, upon demand, for all costs, out-of-pocket expenses and reasonable
attorneys' fees expended or incurred by McKesson in connection with the
development, preparation, negotiation, execution and delivery of this Amendment
and the documents and transactions contemplated hereby.

         C. HEADINGS. Section and subsection headings in this Amendment are
included herein for convenience of reference only and shall not constitute a
part of this Amendment for any other purpose or be given any substantive effect.

         D. APPLICABLE LAW. THIS AMENDMENT SHALL BE GOVERNED BY, AND SHALL BE
CONSTRUED AND ENFORCED IN ACCORDANCE WITH, THE INTERNAL LAWS OF THE STATE OF
CALIFORNIA, WITHOUT REGARD TO CONFLICTS OF LAWS PRINCIPLES.

         E. COUNTERPARTS. This Amendment may be executed in any number of
counterparts, each of which shall be deemed an original, but all such
counterparts together shall constitute but one and the same instrument. Each of
the parties hereto understands and agrees that this document (and any other
document required herein) may be delivered by any party thereto either in the
form of an executed original or an executed original sent by facsimile
transmission to be followed promptly by mailing of a hard copy original, and
that receipt by a party of a facsimile transmitted document purportedly bearing
the signature of the other party shall bind the other party with the same force
and effect as the delivery of a hard copy original. Any failure by a party to
receive the hard copy executed original of such document shall not diminish the
binding effect of receipt of the facsimile transmitted executed original of such
document of the other party.

                                       3
<PAGE>

                  IN WITNESS WHEREOF, the parties hereto have caused this
Amendment to be duly executed and delivered by their respective officers
thereunto duly authorized as of the date first written above.

                               HORIZON PHARMACIES, INC.

                               By:     /s/ Ricky D. McCord
                                  --------------------------------------------
                               Title:  CEO & President
                                     -----------------------------------------

                               McKESSON HBOC, INC.

                               By:    /s/ Alan Pearce
                                  --------------------------------------------
                               Title: Senior Vice President Financial Services
                                     -----------------------------------------

                                       4

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