Document:

Second Amendment to Patent Security Agreement

 Exhibit 10.33 
 SECOND AMENDMENT TO PATENT SECURITY AGREEMENT 
 THIS SECOND AMENDMENT TO PATENT SECURITY AGREEMENT
(the “Amendment”) is entered into as of this 26th day of November, 2002 by and between UNIGENE LABORATORIES, INC., a Delaware corporation, having its principal place of business at 110 Little Falls Road, Fairfield, New Jersey
07004 (the “Company”), and Jay Levy, a resident of New Jersey (the “Secured Party”). 
 W I
T N E S S E T H : 
 WHEREAS, the Company and the Secured Party are parties to that certain Patent Security Agreement dated as of
March 13, 2001 (the “Agreement”), as amended on May 29, 2001, pursuant to which the Company has granted the Secured Party a security interest in certain of its patents and patent applications to secure payment by
the Company of the Obligations (as defined in the Agreement); and 
 WHEREAS, the Secured Party has agreed to execute this Amendment
in connection with the Company’s execution of that certain License and Development Agreement, dated the date hereof, by and between the Company and Upsher-Smith Laboratories, Inc. 
 NOW, THEREFORE, in consideration of the premises, the mutual promises made herein and for other good and valuable consideration, the receipt and
sufficiency of which is hereby acknowledged, the parties hereto agree as follows: 
 1     Amendments. The Agreement is hereby
amended by: 
  

	 	.1	deleting Section 4.1 in its entirety and replacing it with the following 

 The Company owns all of the Collateral free and clear of any lien, encumbrance, mortgage, security agreement, pledge or charge other than a license and development agreement, dated the date hereof, between the Company
and Upsher-Smith Laboratories, Inc., pursuant to which the Company has licensed to Upsher-Smith Laboratories certain rights under the Licensed Patents (as defined in the Upsher-Smith License Agreement) including without limitation
(i) Unigene’s United States Patent No. 6,440,392 issued on August 27, 2002, (ii) Unigene’s United States Patent No. 6,103,495, issued on August 15, 2000 and (iii) Unigene’s United States Patent
No. 4,708,934, issued on November 24, 1987. Secured party acknowledges that Secured Party’s rights under this Agreement are subject to the Upsher-Smith License Agreement. 
  

	 	.2	deleting Exhibit A attached thereto in its entirety and substituting therefore Exhibit A attached to this Amendment. 

 2     No Other Changes. Except as expressly amended hereby, all of the terms and conditions of the Agreement remain in full force and
effect. 
 3     Applicable Law. This Amendment shall be construed in accordance with and governed by the laws of the State
of New Jersey without giving effect to conflicts of laws principles. 
 4     Counterparts. This Amendment may be executed
in two or more counterparts, each of which shall constitute an original and all of which shall constitute the same instrument. 
 IN
WITNESS WHEREOF, the parties hereto have caused this Amendment to be executed on the day and year first above written. 
  

			
	UNIGENE LABORATORIES, INC.
		
	 By:
	 	 /s/ Warren Levy

	 Name:
	 	Warren P. Levy
	 Title:
	 	President & CEO
	
	 /s/ Jay Levy

	JAY LEVY

 EXHIBIT A 
 UNIGENE U.S. Patent Rights 
  

					
	 Patent #
	  	 Title
	  	 Date of Patent

	 US 4,689,220
	  	Immunization by Immunogenic Implant	  	August 25, 1987
			
	 US 4,708,934
	  	Alpha-Amidation Enzyme	  	November 24, 1987
			
	 US 6,319,685
	  	Alpha-Amidation Enzyme (Protein Interference)	  	November 20, 2001
			
	 US 5,789,234
	  	Expression Systems for Amidating Enzyme	  	August 04, 1998
			
	 US 5,912,014
	  	Oral Salmon Calcitonin Pharmaceutical Products	  	June 15, 1999
			
	 US 6,086,918
	  	Oral Peptide Pharmaceutical Products	  	July 11, 2000
			
	 US 6,103,495
	  	Direct Expression of Peptides into Culture Media (Divisional 1)	  	August 15, 2000
			
	 US 6,210,925
	  	Direct Expression of Peptides into Culture Media (Divisional 2)	  	April 3, 2001
			
	 US 6,440,392
	  	Nasal Calcitonin Formulations	  	August 27, 2002
			
	Application
#09/780,870	  	Direct Expression of Peptides into Culture Media (Divisional 3)	  	Filing Date: February 9, 2001
			
	Application
#09/780,643	  	Direct Expression of Peptides into Culture Media (Divisional 4)	  	Filing Date: February 9, 2001
			
	Application
#09/997,465	  	Oral Peptide Pharmaceutical Products	  	Filing Date: November 29, 2001
			
	Application
#10/094,306	  	Oral Peptide Pharmaceutical Dosage Form And Method of Production	  	Filing Date: March 7, 2002Amendment No. 2 to Amended and Restated PCS Services Agreement

 Exhibit 10.6 
 EXECUTION COPY 
 Second Amendment to Amended and Restated PCS Services Agreement 
 Between Sprint Spectrum L.P. and Virgin Mobile USA, L.P. 
 This Second Amendment (“Second Amendment”) is made to that certain Amended and Restated PCS Services Agreement between Sprint Spectrum L.P. (“Sprint PCS”) and Virgin Mobile USA, L.P. (formerly Virgin Mobile
USA, LLC) (“VMU”) dated October 16, 2007, as amended (the “PCS Services Agreement”). Capitalized terms not defined in this Second Amendment are defined in the PCS Services Agreement. 
 WHEREAS, under the terms of the PCS Services Agreement, Sprint PCS is required to compare its actual Cost of Service for certain specified services provided to VMU
during each calendar year with the rates charged to VMU during such year (the “True-up”); 
 WHEREAS, if the actual Cost of Service is more than
$100,000 higher than the rates charged to VMU during such year, VMU is required to pay to Sprint PCS the amount of the difference (“Net Payment”); if the actual Cost of Service is more than $100,000 lower than the rates charged to VMU
during such year, Sprint PCS is required to refund to VMU the amount of such difference (“Net Refund”); 
 WHEREAS, VMU and Sprint PCS desire to
achieve greater certainty with respect to the amounts payable under the PCS Services Agreement for calendar years 2007 and 2008 in a manner that does not adversely affect VMU for such periods; 
 NOW, THEREFORE, in consideration of the mutual promises and agreements herein made and intending to be legally bound hereby, the parties hereto hereby agree to amend the
PCS Services Agreement as follows: 
  

	1.	Section 7.2 (Airtime Pricing; 3G Data Transport Pricing; Transaction-Based Pricing) of the PCS Services Agreement is amended as follows: 

  

	 	a.	Sprint PCS and VMU agree that charges for services during calendar year 2007 will remain fixed at the amounts billed by Sprint PCS according to Exhibit A Pricing Matrix to Schedule
1.1 to the PCS Services Agreement for the corresponding service, and will not be subject to any True-up process and the related payment obligations described in the last two sentences of each of Sections 7.2.1(b), 7.2.2(b) and 7.2.3(b) of the PCS
Services Agreement. 

  

	 	b.	Notwithstanding anything to the contrary in Sections 7.1, 7.2.1(a), 7.2.2(a) and 7.2.3(a) of the PCS Services Agreement, and subject to paragraph 1(c) below, during calendar year
2008, Sprint PCS will charge VMU for each minute of usage under Section 7.2.1(a), for each SMS message under Section 7.2.2(a), and for each megabyte of 3G Data Transport under Section 7.2.3(a) at the 2008 Revised Planning Rates listed in
Exhibit A Pricing Matrix to Schedule 1.1 to the PCS Services Agreement for the corresponding service (“2008 Revised Planning Rates”). 

  

	 	c.	If during calendar year 2008, VMU’s quarterly performance during any of the first three quarters qualifies VMU for an adjustment to VMU’s position in the Profit Margin %
Matrix and consequently an adjustment in the Airtime Pricing Matrix pursuant to Section 7.2.1(a), the SMS Pricing Matrix pursuant to Section 7.2.2(a), and the 3G Data Transport Pricing Matrix pursuant to Section 7.2.3(a), then during the following
quarter Sprint PCS will charge VMU the lesser of (i) the 2008 Revised Planning Rates, or (ii) the 2008 Revised Planning Rates adjusted solely for changes pursuant to the penultimate sentence of Sections 7.2.1(a), 7.2.2(a) and 7.2.3(a) of the PCS
Services Agreement, as applicable. Any revised rates pursuant to the preceding sentence will remain in effect until the earlier of (y) a subsequent adjustment based on VMU’s quarterly performance, or (z) the then current 2009 Planning Rates
take effect pursuant to Section 1(e) below. Any Net Refund provided to VMU or Net Payment provided to Sprint PCS pursuant to Section 1(d) below will take into account any reduction of rates pursuant to this Section 1(c). 

  

	 	d.	Notwithstanding anything to the contrary in Sections 7.1, 7.2.1(b), 7.2.2(b) and 7.2.3(b) of the PCS Services Agreement, for calendar year 2008, if the aggregate actual Cost of
Service is higher than the rates charged to VMU during such year, the Net Payment due to Sprint PCS shall 

  

 EXECUTION COPY 
  

	 	be the amount, if any, by which the lower of (1) the Cost of Service determined based upon the 2008 Revised Planning Rates and (2) the aggregate actual Cost of Service,
exceeds the Cost of Service based upon the rates actually charged to VMU during calendar year 2008 (in the absence of such excess, no Net Payment will be due to Sprint PCS). For the avoidance of doubt, if the True-up for calendar year 2008 results
in a Net Refund to VMU, Sprint PCS will refund such money to VMU in accordance with Sections 7.2.1(b), 7.2.2(b) and 7.2.3(b) of the PCS Services Agreement. 

  

	 	e.	Subject to paragraphs 1(b) and 1(d) above, Sprint PCS will continue to be obligated during calendar year 2008, to update the Airtime Pricing Matrix pursuant to Section 7.2.1(c), the
SMS Pricing Matrix pursuant to Section 7.2.2(c), and the 3G Data Transport Pricing Matrix pursuant to Section 7.2.3(c) and to provide the quarterly notifications pursuant to Sections 7.2.1(d), 7.2.2(d) and 7.2.3(d). Beginning with the first quarter
of calendar year 2009, the True-up and pricing process and obligations set forth in Sections 7.2.1(a), 7.2.1(b) and 7.2.1(c), Sections 7.2.2(a), 7.2.2(b) and 7.2.2(c), and Sections 7.2.3(a), 7.2.3(b) and 7.2.3(c) of the PCS Services Agreement will
apply unless otherwise agreed by the parties. 

  

	2.	Except as specifically provided above, the PCS Services Agreement remains in effect in accordance with its terms. 

 IN WITNESS HEREOF, the parties have executed this Second Amendment as of the dates indicated below. 
  

									
	SPRINT SPECTRUM, L.P.	 		 	VIRGIN MOBILE USA, L.P. (formerly Virgin Mobile USA, LLC) Company Name
					
	By:	 	/S/    THAD LANGFORD	 		 	By:	 	/S/    PETER LURIE
		 		 		 		 	
	Name:	 	Thad Langford	 		 	Name:	 	Peter Lurie
					
	Its:	 	Vice President, Strategic Partners	 		 	Its:	 	General Counsel
					
	Date:	 	March 12, 2008	 		 	Date:	 	March 12, 2008

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