Document:

EX-10.9

 Exhibit 10.9 
  

 
 December 23, 2020 
 Uri
A. Lopatin, M.D. 
 [***] 
 [***] 

Dear Uri: 
 Pardes Biosciences, Inc, a Delaware
corporation (the “Company”), is pleased to amend and restate the terms of your employment with the Company pursuant to the terms of this Amended and Restated Executive Offer Letter (the “Agreement”). This Agreement
amends and restates the terms of that certain offer letter dated April 27, 2020 by and between you and the Company. 
 Duties and Extent of
Service 
 As Chief Executive Officer of the Company, you will report directly to the Board of Directors of the Company (the
“Board”) and you will have responsibility for performing those duties as are customary for, and are consistent with, your position with the Company, as well as those duties as the Board may designate. Your first date of employment
was February 29, 2020. Your primary working location shall initially be your home; provided that if the Company were to establish an office no more than a 50 mile radius from the address set forth above, the Company shall be entitled to
designate such location as your primary working location. Subject to the terms of this Agreement, the Company reserves the right to reasonably require you to perform your duties at places other than your primary working location from time to time
and to require business travel. 
 You agree to abide by the rules, regulations, instructions, personnel practices and policies of the
Company and any changes therein that may be adopted by the Company. Except for vacations and absences due to temporary illness, you will be expected to devote your full-time business efforts to the business and affairs of the Company.
Notwithstanding the foregoing, you may participate in outside charitable, civic, educational, professional, community or industry activities to the extent such activities do not individually or in the aggregate materially interfere with the
performance of your duties to the Company as provided in this Agreement or create an actual or potential conflict of interest with the Company’s business; provided, further, that your service on any outside boards (whether for
profit or non-profit) shall require the prior consent of the Board. Any of your outside activities listed on Schedule 1 attached hereto shall also be deemed approved for purposes of this Agreement and shall
not be a violation of your obligations in this paragraph. 
 Employment at Will 

You and the Company understand and agree that you are an employee at-will, and that you may resign, or
the Company may terminate your employment, at any time and for any or for no reason in accordance with the termination provisions set forth further below in this Agreement. Nothing in this Agreement shall be construed to alter the at-will nature of your employment, nor shall anything in this Agreement be construed as providing you with a definite term of employment. 

 Uri A. Lopatin, M.D. 

December 23, 2020 
  Page
 2
 
  

 Compensation 

Until the termination of your employment, in consideration for your services hereunder, we will compensate you as follows: 

 

	 	•	 	 Base Salary. Your initial annual base salary as of commencement of employment was initially $200,000 per
year, payable in accordance with the Company’s standard payroll schedule (the “Base Salary”). Upon completion of a financing with aggregate gross proceeds to the Company in excess of $4,000,000 but less than or equal to
$8,000,000, your Base Salary was automatically increased to the annualized rate of $300,000 effective upon the closing of such financing. Upon completion of an Equity Financing (as defined below), your Base Salary shall automatically increase to an
annualized rate of $450,000 effective upon the closing of such Equity Financing. The Base Salary may be reviewed and modified from time to time at the sole discretion of the Board or any committee designated by the Board to govern compensation
matters (the “Compensation Committee”) and is in addition to the other benefits set forth herein. 

  

	 	•	 	 Base Salary Deferral. You and the Company executed that certain salary deferral agreement dated as of
July 7, 2020, a copy of which is attached hereto as Exhibit A (the “Salary Deferral Agreement”). Per the Salary Deferral Agreement, you acknowledge that the Time-Based Deferral End Date referenced in the Salary Deferral
Agreement was extended by the Company to December 30, 2020. By execution below, you and the Company agree that the Time-Based Deferral End Date shall be extended to March 15, 2021. 

 

	 	•	 	 Annual Bonus. You will be eligible to receive an annual bonus with a target payout equal to fifty
percent (50%) of your Base Salary paid for the relevant fiscal year in accordance with the terms of any Company bonus plan adopted by the Board or the Compensation Committee. The determination of whether you will receive a bonus with respect to
any given fiscal year of the Company, and the amount of any such bonus, shall be determined by the Board or its Compensation Committee, in its sole discretion, after considering your performance and the Company’s performance for such fiscal
year. If you are awarded a bonus with respect to a given fiscal year of the Company, the Company will make payment of such bonus no later than March 15 of the next fiscal year of the Company. Except as provided under the heading
“Severance” below, a precondition to the annual bonus being considered earned is that you continuously remain an employee of the Company on the date on which any such annual bonus is paid. 

 

	 	•	 	 Vacation; PTO. You will be entitled to paid vacation in accordance with the Company’s then-current
vacation policy. 

  

	 	•	 	 Benefits. You will also be entitled to participate in such benefits (including group medical, vision and
dental insurance), if any, as the Company shall make available to executive-level employees and in such employee benefit plans and fringe benefits as may be offered or made available by the Company to its employees. The Company shall not
unreasonably delay your ability to participate in such benefit plans and/or fringe benefit programs once such benefit plans and/or fringe benefits are available to employees. The Board reserves the right to change or terminate the Company’s
employee benefit plans and fringe benefits. Your participation in such employee benefit plans and fringe benefits, and the amount and nature of the benefits to which you shall be entitled thereunder or in connection therewith, shall be subject to
the terms and conditions of such employee benefit plans and fringe benefits. 

  

	 	•	 	 Expenses. Upon delivery of reasonable documentation, you will be entitled to reimbursement by the Company
during the term of your employment for reasonable travel, business development, and other business expenses incurred by you in the performance of your duties hereunder in accordance with the then-current policies and practices of the Company.

 Uri A. Lopatin, M.D. 

December 23, 2020 
  Page
 3
 
  

	 	•	 	 Initial Equity Award and Future Equity Awards. In connection with your commencement of employment, the
Company granted you a restricted stock award of 4,000,000 shares of the Company’s common stock (the “Shares”) pursuant to a restricted stock purchase agreement dated as of February 29, 2020 (the “Restricted Stock
Purchase Agreement”) between Executive and the Company which sets forth the terms of the award. Following your execution of this Agreement and subject to the approval of you and the Company’s Board of Directors, the Restricted Stock
Purchase Agreement shall be amended, as deemed necessary by the Company, to reflect the terms of this Agreement. In addition to the foregoing, you shall be eligible to receive grants of Company equity awards in the sole discretion of and subject to
the approval of the Board or its Compensation Committee. 

 Severance 

 

	 	•	 	 Termination Without Cause or Resignation for Good Reason following an Equity Financing. Following the
completion of an Equity Financing (which term is defined below in this Agreement), in the event that the Company terminates your employment other than due to: (i) Cause (which term is defined below in this Agreement), or (ii) your
death or disability, or in the event that you terminate your employment with the Company for Good Reason (which term is defined below in this Agreement), then, subject to the condition precedent of your execution and delivery of the Company’s
standard form general release to be delivered to you at the time of your termination, which release becomes irrevocable within sixty (60) days following your termination, you will be entitled to the following severance benefits (the “Non-CIC Severance Benefits”): 

  

	 	(i)	 your Base Salary for a period of twelve (12) months following your termination of employment (such
applicable period, the “Severance Period”), which amount shall be paid in equal installments on the Company’s regular payroll schedule and will be subject to applicable tax withholdings over the period outlined above following
the date of your termination of employment; provided, however, that no payments will be made prior to the sixtieth (60th) day following your termination of employment. On the sixtieth (60th) day following your termination of employment, the Company will pay you in a lump sum the Base Salary that you would have received on or prior to such date under the original schedule but for the
delay while waiting for the sixtieth (60th) day in compliance with Section 409A (as defined below) and the effectiveness of the release, with the balance of the Base Salary being paid as originally scheduled. For such purposes, your final Base
Salary will be calculated at the rate in effect as of the effective date of termination of your employment and prior to giving effect to any reduction in Base Salary that would give rise to your right to resign for Good Reason;

  

	 	(ii)	 if you are eligible for and timely elect to continue your health insurance coverage under the Company’s
group health plans under the Consolidated Omnibus Budget Reconciliation Act of 1985 or the state equivalent (“COBRA”) following your termination date, the Company will pay the COBRA group health insurance premiums for you and your
eligible dependents until the earliest of (A) the close of the Severance Period, (B) the expiration of your eligibility for the continuation coverage under COBRA, or (C) the date when you become eligible for substantially equivalent
health insurance coverage in connection with new employment or self-employment. For purposes of this Section, references to COBRA premiums shall not include any amounts payable by you under a Section 125 health care reimbursement plan under the
Internal Revenue Code of 1986, as amended (the “Code”). 

 Uri A. Lopatin, M.D. 

December 23, 2020 
  Page
 4
 
  

	 	
Notwithstanding the foregoing, if at any time the Company determines, in its sole discretion, that it cannot pay the COBRA premiums without potentially incurring financial costs or penalties
under applicable law (including, without limitation, Section 2716 of the Public Health Service Act), then regardless of whether you elect continued health coverage under COBRA, and in lieu of providing the COBRA premiums, the Company will
instead pay you on the last day of each remaining month of the Severance Period, a fully taxable cash payment equal to the COBRA premiums for that month, subject to applicable tax withholdings (such amount, the “Health Care Benefit
Payment”). The Health Care Benefit Payment shall be paid in monthly installments on the same schedule that the COBRA premiums would otherwise have been paid and shall be equal to the amount that the Company would have otherwise paid for
COBRA premiums, and shall be paid until the earlier of (i) expiration of the Severance Period or (ii) the date when you become eligible for substantially equivalent health insurance coverage in connection with new employment or
self-employment; 

  

	 	(iii)	 the vesting of all outstanding equity awards held by you shall be accelerated so that the amount of shares
vested under such equity award shall equal that number of shares which would have been vested if you had continued to render services to the Company through the Severance Period; and 

 

	 	(iv)	 outplacement assistance, in duration and amounts that are determined by the Company to be reasonable in its
sole discretion. 

  

	 	•	 	 Termination Without Cause or Resignation for Good Reason During a Change in Control Period. In the event
that the Company terminates your employment other than due to: (i) Cause, or (ii) your death or disability, or you terminate your employment with the Company for Good Reason, in each case at any time during the Change in Control Period
(which term is defined below in this Agreement) then, subject to the condition precedent of your execution and delivery of the Company’s standard form general release to be delivered to you at the time of your termination, which release becomes
irrevocable within sixty (60) days following your termination, you will be entitled to the following severance benefits (the “CIC Severance Benefits”) in lieu of any Non-CIC Severance
Benefits (and for the avoidance of doubt: (x) in no event will you be entitled to both the Non-CIC Severance Benefits and the CIC Severance Benefits, and (y) if the Company has commenced providing
the Non-CIC Severance Benefits to you prior to the date that you become eligible to receive the CIC Severance Benefits, the Non-CIC Severance Benefits previously
provided to you (or your beneficiaries or estate, as applicable) shall reduce the CIC Severance Benefits provided below): 

  

	 	(i)	 your Base Salary for a period of twelve (12) months following your termination of employment (such period,
the “CIC Severance Period”), which amount shall be paid in equal installments on the Company’s regular payroll schedule and will be subject to applicable tax withholdings over the period outlined above following the date of
your termination of employment; provided, however, that no payments will be made prior to the sixtieth (60th) day following your termination of employment. On the sixtieth (60th) day following your termination of employment, the Company will pay you in a lump sum the Base Salary that you would have received on or prior to such date under the original schedule but for the
delay while waiting for the sixtieth (60th) day in compliance with Section 409A (as defined below) and the effectiveness of the release, with the balance of the Base Salary being paid as originally scheduled. For such purposes, your final Base
Salary will be calculated at the rate in effect as of the effective date of termination of your employment with the Company and prior to giving effect to any reduction in Base Salary that would give rise to your right to resign for Good Reason;

 Uri A. Lopatin, M.D. 

December 23, 2020 
  Page
 5
 
  

	 	(ii)	 a lump sum payment in an amount equal to your target annual bonus for the Company’s then-current fiscal
year, which payment shall be paid on the Company’s first standard payroll date following the later of (A) the date that is sixty (60) days following your date of termination, but in no event more than seventy-five (75) days
thereafter, or (B) the date of the Change in Control; 

  

	 	(iii)	 if you are eligible for and timely elect to continue your health insurance coverage under the Company’s
group health plans under COBRA following your termination date, the Company will pay the COBRA group health insurance premiums for you and your eligible dependents until the earliest of (A) the close of the CIC Severance Period, (B) the
expiration of your eligibility for the continuation coverage under COBRA, or (C) the date when you become eligible for substantially equivalent health insurance coverage in connection with new employment or self-employment. For purposes of this
Section, references to COBRA premiums shall not include any amounts payable by you under a Section 125 health care reimbursement plan under the Code. Notwithstanding the foregoing, if at any time the Company determines, in its sole discretion,
that it cannot pay the COBRA premiums without potentially incurring financial costs or penalties under applicable law (including, without limitation, Section 2716 of the Public Health Service Act), then regardless of whether you elect continued
health coverage under COBRA, and in lieu of providing the COBRA premiums, the Company will instead pay you on the last day of each remaining month of the CIC Severance Period, a fully taxable cash payment equal to the Health Care Benefit Payment.
The Health Care Benefit Payment shall be paid in monthly installments on the same schedule that the COBRA premiums would otherwise have been paid and shall be equal to the amount that the Company would have otherwise paid for COBRA premiums, and
shall be paid until the earlier of (i) expiration of the CIC Severance Period or (ii) the date when you become eligible for substantially equivalent health insurance coverage in connection with new employment or self-employment;

  

	 	(iv)	 If such termination is due to the Company terminating your employment for any reason (other than Cause or due
to your death or disability) or your termination of your employment with the Company for Good Reason, then the vesting of all outstanding equity awards held by you shall be accelerated on the later of (A) the date of your termination or
(B) the date of such Change in Control, so that all such equity awards shall be deemed to be fully vested. In addition, subject to the terms of the Company’s equity plan, any such equity awards that are stock options may be exercised by
you (or your legal guardian or legal representative) until the latest of (x) three (3) months after the date of your termination of employment (y) with respect to any portion of such equity awards that become exercisable on the date of a
Change in Control pursuant to this clause (iv), three (3) months after the date of the Change in Control, or (z) such longer period as may be specified in the applicable equity award agreement; provided, however, that in no event shall any
equity award that is a stock option remain exercisable beyond the original outside expiration date of such equity award; and 

  

	 	(v)	 outplacement assistance, in duration and amounts that are determined by the Company to be reasonable in its
sole discretion. 

 Uri A. Lopatin, M.D. 

December 23, 2020 
  Page
 6
 
  

 Certain Definitions. 

For purposes of this Agreement, the following definitions shall be applicable: 

“Cause” shall mean any one or more of the following: (i) your intentional commission of an act, or intentional failure to
act, that materially injures the business of the Company; provided, however, that in no event shall any business judgment made in good faith by you and within your defined scope of authority constitute a basis for termination for Cause
under this Agreement; (ii) your intentional refusal or intentional failure to act in accordance with any lawful and proper direction or order of the Board; (iii) your material breach of your fiduciary, statutory, contractual, or common law
duties to the Company (including any material breach of this Agreement, the Proprietary Rights Agreement (as defined below), or the Company’s written policies); (iv) your indictment for or conviction of any felony or any crime involving
dishonesty; or (v) your participation in any fraud or other act of willful misconduct against the Company; provided, however, that in the event that any of the foregoing events is reasonably capable of being cured, the Company
shall provide written notice to you describing the nature of such event and you shall thereafter have twenty (20) days to cure such event. 

“Change in Control” shall mean (1) a sale of all or substantially all of the Company’s assets other than to an
Excluded Entity, (2) a merger, consolidation or other capital reorganization or business combination transaction of the Company with or into another corporation, limited liability company or other entity other than an Excluded Entity, or
(3) the consummation of a transaction, or series of related transactions, in which any “person” (as such term is used in Sections 13(d) and 14(d) of the Exchange Act) becomes the “beneficial owner” (as defined in Rule 13d-3 of the Exchange Act), directly or indirectly, of all of the Company’s then outstanding voting securities. Notwithstanding the foregoing, a transaction shall not constitute a Change of Control if its
purpose is to (A) change the jurisdiction of the Company’s incorporation, (B) create a holding company that will be owned in substantially the same proportions by the persons who hold the Company’s securities immediately before
such transaction, or (C) obtain funding for the Company in a financing that is approved by the Company’s Board. An “Excluded Entity” means a corporation, limited liability company or other entity of which the holders of
voting capital stock of the Company outstanding immediately prior to such transaction are the direct or indirect holders of voting securities representing at least a majority of the votes entitled to be cast by all of such corporation’s,
limited liability company’s or other entity’s voting securities outstanding immediately after such transaction. As used in this Agreement, the consummation of (i) a transaction or series of related transactions in which any
“person” or “group” (within the meaning of Section 13(d) and 14(d) of the Securities Exchange Act of 1934, as amended), becomes the “beneficial owner” (as defined in Rule
13d-3 under the Securities Exchange Act of 1934, as amended), directly or indirectly, of more than 50% of the outstanding voting securities of the Company having the right to vote for the election of members
of the Company’s board of directors, (ii) any reorganization, merger or consolidation of the Company, other than a transaction or series of related transactions in which the holders of the voting securities of the Company outstanding
immediately prior to such transaction or series of related transactions retain, immediately after such transaction or series of related transactions, at least a majority of the total voting power represented by the outstanding voting securities of
the Company or such other surviving or resulting entity or (iii) a sale, lease or other disposition of all or substantially all of the assets of the Company; provided, however, that following the Company’s IPO, “Change in
Control” shall have the meaning described in the Company’s stock plan adopted by the Company in connection with the Company’s IPO. 

“Change in Control Period” means the three (3) months prior to or within one (1) year after such Change in Control.

 Uri A. Lopatin, M.D. 

December 23, 2020 
  Page
 7
 
  

 “Equity Financing” means the consummation of a bona fide transaction or
series of transactions with the principal purpose of raising capital, pursuant to which the Company issues and sells in excess of $10,000,000 of preferred stock at a fixed valuation, including but not limited to, a
pre-money or post-money valuation. 
 “Good Reason” means any one or more of the
following: (i) a material diminution in the nature or scope of your duties; (ii) a material reduction in your Base Salary (other than as part of a reduction in the base salaries of all or substantially all other senior executives of the
Company that is in the same proportion as the reduction in your Base Salary); and (iii) the permanent, non-voluntary relocation of your principal place of employment with the Company to a location that
increases your one-way commuting distance by more than fifty (50) miles as compared to your then-current principal place of employment immediately prior to such relocation. In order for you to resign for
Good Reason, each of the following requirements must be met: (A) you much provide written notice to the Board within sixty (60) calendar days after the first occurrence of the event giving rise to Good Reason setting forth the basis for
your resignation; (B) you must allow the Company at least twenty (20) days from receipt of such written notice from you sufficiently describing such alleged Good Reason to cure such event; (C) such event must not be cured by the
Company within such twenty (20) day period; and (D) you must resign for Good Reason not later than sixty (60) days after the expiration of the foregoing cure period. 

“IPO” means the Company’s initial public offering of shares of its common stock pursuant to an effective Registration
Statement on Form S-1. 
 Withholding Taxes 

All payments and benefits described in this Agreement or that you may otherwise be entitled or eligible to receive as a result of your
employment with the Company will be subject to applicable federal, state and local tax withholdings. 
 409A Compliance 

It is intended that all of the severance benefits and other payments payable under this Agreement satisfy, to the greatest extent possible, the
exemptions from the application of Section 409A of the Code (the “Section 409A”), provided under Treasury Regulations 1.409A 1(b)(4), 1.409A 1(b)(5) and 1.409A 1(b)(9), and this Agreement will be construed to
the greatest extent possible as consistent with those provisions, and to the extent not so exempt, this Agreement (and any definitions hereunder) will be construed in a manner that complies with Section 409A. In furtherance of the foregoing,
the severance payments payable under the heading “Severance” shall be paid no later than the last date permitted in order to satisfy the exemption from Section 409A under Treasury Regulations 1.409A 1(b)(4). For purposes of
Section 409A (including, without limitation, for purposes of Treasury Regulation Section 1.409A 2(b)(2)(iii)), your right to receive any installment payments under this Agreement (whether severance payments, reimbursements or otherwise)
shall be treated as a right to receive a series of separate payments and, accordingly, each installment payment hereunder shall at all times be considered a separate and distinct payment. Notwithstanding any provision to the contrary in this
Agreement, to the extent any payments to you pursuant to this Agreement constitute “nonqualified deferred compensation” subject to Section 409A of the Code or are intended to be exempt from Section 409A of the Code pursuant to
Treasury Regulation Section 1.409A-1(b)(9)(iii), then, to the extent required by Section 409A of the Code or to satisfy such exception, no amount shall be payable pursuant to such sections unless
your termination of employment constitutes a “separation from service” with the Company (as such term is defined in Treasury Regulation Section 1.409A-1(h) and any successor provision thereto)
(a “Separation from Service”). Notwithstanding any provision to the contrary in this Agreement, if you are deemed by the Company at the time of your 

 Uri A. Lopatin, M.D. 

December 23, 2020 
  Page
 8
 
  

 
Separation from Service under Section 409A to be a “specified employee” for purposes of Section 409A(a)(2)(B)(i), and if any of the payments upon Separation from Service set
forth herein and/or under any other agreement with the Company are deemed to be “deferred compensation”, then to the extent delayed commencement of any portion of such payments is required in order to avoid a prohibited distribution under
Section 409A(a)(2)(B)(i) and the related adverse taxation under Section 409A, such payments shall not be provided to you prior to the earliest of (i) the expiration of the six-month and one day
period measured from the date of your Separation from Service with the Company, or (ii) such earlier date as permitted under Section 409A without the imposition of adverse taxation. Upon the first business day following the expiration of
such applicable Section 409A(a)(2)(B)(i) period, all payments deferred pursuant to this paragraph shall be paid in a lump sum to you, and any remaining payments due shall be paid as otherwise provided herein or in the applicable agreement. No
interest shall be due on any amounts so deferred. If the Company determines that any severance benefits provided under this Agreement constitute “nonqualified deferred compensation” under Section 409A, for purposes of determining the
schedule for payment of the severance benefits, any such severance benefits shall not be paid, or in the case of installments shall not commence payment, until the sixtieth (60th) day following the Separation from Service or other applicable payment
event. In addition to the above, to the extent required to comply with Section 409A and the applicable regulations and guidance issued thereunder, if the applicable deadline for you to execute (and not revoke) the applicable release spans two
calendar years, payment of the applicable severance benefits shall not commence until the beginning of the second calendar year. To the extent required to avoid accelerated taxation and/or tax penalties under Section 409A, amounts reimbursable
to you under this Agreement shall be paid to you on or before the last day of the year following the year in which the expense was incurred and the amount of expenses eligible for reimbursement (and in-kind
benefits provided to you) during any one year may not effect amounts reimbursable or provided in any subsequent year. The Company makes no representation that any or all of the payments described in this Agreement will be exempt from or comply with
Section 409A and makes no undertaking to preclude Section 409A from applying to any such payment. Notwithstanding the foregoing if a Change in Control would give rise to a payment or settlement event with respect to any payment or benefit
that constitutes “nonqualified deferred compensation,” the transaction or event constituting the Change in Control must also constitute a “change in control event” (as defined in Treasury Regulation
§1.409A-3(i)(5)) in order to give rise to the payment or settlement event for such payment or benefit, to the extent required by Section 409A. 

Nondisclosure and Developments 
 As
a condition of your employment you shall sign the Company’s standard employee Confidential Information and Invention Assignment Agreement (the “Proprietary Rights Agreement”), which you executed on February 29, 2020. 

No Conflicting Obligation 
 You
hereby represent and warrant that as of April 27, 2020 and as of the execution and delivery of this Agreement, the performance by you of any or all of the terms of this Agreement and the performance by you of your duties as an employee of the
Company do not and will not breach or contravene (i) any agreement or contract (including, without limitation, any employment or consulting agreement, any agreement not to compete or any confidentiality or nondisclosure agreement) to which you
are or may become a party on or at any time after your commencement of employment or (ii) any obligation you may otherwise have under applicable law to any former employer or to any person to whom you have provided, provide or will provide
consulting services. You hereby further represent and warrant to the Company that, prior to the date your employment commenced, you provided to the Company a copy of any and all potentially conflicting agreements for the Company’s review. 

 Uri A. Lopatin, M.D. 

December 23, 2020 
  Page
 9
 
  

 Defend Trade Secrets Act Notice of Immunity Rights 

You acknowledge that the Company has provided you with the following notice of immunity rights in compliance with the requirements of the
Defend Trade Secrets Act: (i) you shall not be held criminally or civilly liable under any Federal or State trade secret law for the disclosure of proprietary information that is made in confidence to a Federal, State, or local government
official or to an attorney solely for the purpose of reporting or investigating a suspected violation of law; (ii) you shall not be held criminally or civilly liable under any Federal or State trade secret law for the disclosure of proprietary
information that is made in a complaint or other document filed in a lawsuit or other proceeding, if such filing is made under seal; and (iii) if you file a lawsuit for retaliation by the Company for reporting a suspected violation of law, you
may disclose the proprietary information to your attorney and use the proprietary information in the court proceeding, if you file any document containing the proprietary information under seal, and do not disclose the proprietary information,
except pursuant to court order. 
 Termination 

You acknowledge that the employment relationship between the Company and you is at-will, meaning that
the employment relationship may be terminated by the Company or you for any reason or for no reason. Either party may terminate your employment with the Company at any time and for any or no reason upon thirty (30) days prior written notice;
provided that the Company may terminate you for Cause and you may resign for Good Reason at any time upon written notice. 

Regardless of the reason your employment with the Company terminates, you will continue to comply with the Proprietary Rights Agreement
contemplated hereby. 
 Work Eligibility 

You agree that prior to the commencement of employment, you will provide the Company with sufficient documentation to demonstrate your
eligibility to work in the United States and, at the request of the Company, shall provide any additional documentation requested by the Company to demonstrate your eligibility to work in the United States. 

Governing Law 
 This Agreement
shall be governed by and construed in accordance with the internal substantive laws of the State of California. 
 Dispute Resolution 

To ensure the rapid and economical resolution of disputes that may arise in connection with your employment with the Company, you and the
Company agree that any and all disputes, claims, or causes of action, in law or equity, including but not limited to statutory claims, arising from or relating to the enforcement, breach, performance, or interpretation of this Agreement, your
employment with the Company, or the termination of your employment from the Company, will be resolved pursuant to the Federal Arbitration Act, 9 U.S.C. §1-16, and to the fullest extent permitted by law,
by final, binding and confidential arbitration conducted in San Francisco, California by JAMS, Inc. (“JAMS”) or its successors, under JAMS’ then applicable rules and procedures for employment disputes (which can be found at
http://www.jamsadr.com/rules-clauses/, and which will be provided to you on request); provided that the arbitrator shall: (a) have the authority to compel adequate discovery for the resolution of the dispute and to award such relief as
would otherwise be permitted by law; and (b) issue a written arbitration decision 

 Uri A. Lopatin, M.D. 

December 23, 2020 
  Page
 10
 
  

 
including the arbitrator’s essential findings and conclusions and a statement of the award. You and the Company shall be entitled to all rights and remedies that either would be entitled to
pursue in a court of law. BOTH YOU AND THE COMPANY ACKNOWLEDGE THAT BY AGREEING TO THIS ARBITRATION PROCEDURE, YOU AND THE COMPANY WAIVE THE RIGHT TO RESOLVE ANY SUCH DISPUTE THROUGH A TRIAL BY JURY OR JUDGE OR ADMINISTRATIVE PROCEEDING. The Company
shall pay all filing fees in excess of those which would be required if the dispute were decided in a court of law, and shall pay the arbitrator’s fee. Nothing in this Agreement is intended to prevent either the Company or you from obtaining
injunctive relief in court to prevent irreparable harm pending the conclusion of any such arbitration. This section is intended to be the exclusive method for resolving any and all claims by the parties against each other for payment of damages
under this Agreement or relating to your employment; provided, however, that you shall retain the right to file administrative charges with or seek relief through any government agency of competent jurisdiction, and to participate in
any government investigation, including but not limited to (i) claims for workers’ compensation, state disability insurance or unemployment insurance; (ii) claims for unpaid wages or waiting time penalties brought before the
California Division of Labor Standards Enforcement (or any similar agency in any applicable jurisdiction other than California); provided, however, that any appeal from an award or from denial of an award of wages and/or waiting time
penalties shall be arbitrated pursuant to the terms of this Agreement; and (iii) claims for administrative relief from the United States Equal Employment Opportunity Commission and/or the California Department of Fair Employment and Housing (or
any similar agency in any applicable jurisdiction other than California); provided, further, that you shall not be entitled to obtain any monetary relief through such agencies other than workers’ compensation benefits or
unemployment insurance benefits. 
 Entire Agreement; Amendment 

This Agreement (together with the Proprietary Rights Agreement and the Salary Deferral Agreement contemplated hereby) sets forth the sole and
entire agreement and understanding between the Company and you with respect to the specific matters contemplated and addressed hereby and thereby. No prior agreement, whether written or oral, shall be construed to change or affect the operation of
this Agreement in accordance with its terms, and any provision of any such prior agreement, which conflicts with or contradicts any provision of this Agreement, is hereby revoked and superseded. Any prior agreement, if any, you may have with the
Company regarding your employment, whether written or oral, is hereby, and without any further action on your part or the Company’s, terminated, revoked and superseded by this Agreement. This Agreement may be amended or terminated only by a
written instrument executed both by you and the Company. 
 Notices 

Any notices provided must be in writing and will be deemed effective upon the earlier of personal delivery (including personal delivery by fax)
or the next day after sending by overnight carrier, to the Company at its primary office location and to you at the address as listed on the Company payroll. 

Severability 
 Whenever possible,
each provision of this Agreement will be interpreted in such manner as to be effective and valid under applicable law, but if any provision of this Agreement is held to be invalid, illegal or unenforceable in any respect under any applicable law or
rule in any jurisdiction, such invalidity, illegality or unenforceability will not affect any other provision or any other jurisdiction, but this Agreement will be reformed, construed and enforced in such jurisdiction to the extent possible in
keeping with the intent of the Parties. 

 Uri A. Lopatin, M.D. 

December 23, 2020 
  Page
 11
 
  

 Waiver 

Any waiver of any breach of any provisions of this Agreement must be in writing to be effective, and it shall not thereby be deemed to have
waived any preceding or succeeding breach of the same or any other provision of this Agreement. 
 Counterparts 

This Agreement may be executed in separate counterparts, any one of which need not contain signatures of more than one party, but both of which
taken together will constitute one and the same Agreement. 
 Headings 

The headings of the sections and paragraphs hereof are inserted for convenience only and shall not be deemed to constitute a part hereof nor to
affect the meaning thereof. 
 Indemnification and Director’s and Officer’s Insurance 

The Company will indemnify you to the fullest extent permitted by the laws of the State of Delaware, as in effect at the time of the subject
act or omission, and you shall be entitled to the protection of any insurance policies the Company may elect to maintain generally for the benefit of its directors and officers. 

Successors and Assigns 
 This
Agreement is intended to bind and inure to the benefit of and be enforceable by you and the Company, and your respective successors, assigns, heirs, executors and administrators, except that you may not assign any of your duties hereunder and you
may not assign any of your rights hereunder without the written consent of the Company, which shall not be withheld unreasonably. 

[Signature Page Follows] 

 Uri A. Lopatin, M.D. 

December 23, 2020 
  Page
 12
 
  

 Please acknowledge your acceptance of the terms of this Agreement by signing below and
returning a copy to me. 
  

			
	 Sincerely,

	
	PARDES BIOSCIENCES, INC.
		
	 By:
	 	 /s/ Uri Lopatin, M.D.

		 	 Name: Uri Lopatin, M.D.

		 	Title: President and CEO

  

			
	Accepted and Agreed:	 	
	
	I hereby acknowledge that I have had a full and adequate opportunity to read, understand and discuss the terms and conditions contained in this Agreement prior to signing hereunder.
		
	 /s/ Uri A. Lopatin, M.D.
	 	
	 Uri A. Lopatin, M.D.
	 	
	 Date:12/23/2020EX-10.10

 Exhibit 10.10 

 
 

 
 December 23, 2020 
 Lee
D. Arnold, Ph.D. 
 [***] 
 [***] 

Dear Lee: 
 Pardes Biosciences, Inc, a Delaware
corporation (the “Company”), is pleased to amend and restate the terms of your employment with the Company pursuant to the terms of this Amended and Restated Executive Offer Letter (the
“Agreement”).    This Agreement amends and restates the terms of that certain offer letter dated April 6, 2020 by and between you and the Company. 

Duties and Extent of Service 
 As
Chief Scientific Officer of the Company, you will report directly to the President and Chief Executive Officer of the Company (the “Supervising Officer”) and you will have responsibility for performing those duties as are customary
for, and are consistent with, your position with the Company, as well as those duties as the Supervising Officer or the Board of Directors of the Company (the “Board”) may designate. Your first date of employment was April 6,
2020. Your primary working location shall initially be your home; provided that if the Company were to establish an office no more than a 50 mile radius from the address set forth above, the Company shall be entitled to designate such location as
your primary working location. Subject to the terms of this Agreement, the Company reserves the right to reasonably require you to perform your duties at places other than your primary working location from time to time and to require business
travel. 
 You agree to abide by the rules, regulations, instructions, personnel practices and policies of the Company and any changes
therein that may be adopted by the Company. Except for vacations and absences due to temporary illness, you will be expected to devote your full-time business efforts to the business and affairs of the Company. Notwithstanding the foregoing, you may
participate in outside charitable, civic, educational, professional, community or industry activities to the extent such activities do not individually or in the aggregate materially interfere with the performance of your duties to the Company as
provided in this Agreement or create an actual or potential conflict of interest with the Company’s business; provided, further, that your service on any outside boards (whether for profit or
non-profit) shall require the prior consent of the Supervising Officer. Any of your outside activities listed on Schedule 1 attached hereto shall also be deemed approved for purposes of this Agreement and
shall not be a violation of your obligations in this paragraph. 
 Employment at Will 

You and the Company understand and agree that you are an employee at-will, and that you may resign, or the Company may
terminate your employment, at any time and for any or for no reason in accordance with the termination provisions set forth further below in this Agreement. Nothing in this Agreement shall be construed to alter the
at-will nature of your employment, nor shall anything in this Agreement be construed as providing you with a definite term of employment. 

 Lee D. Arnold, Ph.D. 

December 23, 2020 
  Page
 2
 
  

 Compensation 

Until the termination of your employment, in consideration for your services hereunder, we will compensate you as follows: 

 

	 	•	 	 Base Salary. Your initial annual base salary shall be at the annualized rate of $320,000, payable in
accordance with the Company’s standard payroll schedule (the “Base Salary”). Upon completion of an Equity Financing (as defined below), your Base Salary shall automatically increase to an annualized rate of $366,000 effective
upon the closing of such Equity Financing. The Base Salary may be reviewed and modified from time to time at the sole discretion of the Board or any committee designated by the Board to govern compensation matters (the “Compensation
Committee”) and is in addition to the other benefits set forth herein. 

  

	 	•	 	 Annual Bonus. You will be eligible to receive an annual bonus with a target payout equal to forty
percent (40%) of your Base Salary paid for the relevant fiscal year in accordance with the terms of any Company bonus plan adopted by the Board or the Compensation Committee. The determination of whether you will receive a bonus with respect to
any given fiscal year of the Company, and the amount of any such bonus, shall be determined by the Board or its Compensation Committee, in its sole discretion, after considering your performance and the Company’s performance for such fiscal
year. If you are awarded a bonus with respect to a given fiscal year of the Company, the Company will make payment of such bonus no later than March 15 of the next fiscal year of the Company. Except as provided under the heading
“Severance” below, a precondition to the annual bonus being considered earned is that you continuously remain an employee of the Company on the date on which any such annual bonus is paid. 

 

	 	•	 	 Vacation; PTO. You will be entitled to paid vacation in accordance with the Company’s then-current
vacation policy. 

  

	 	•	 	 Benefits. You will also be entitled to participate in such benefits (including group medical, vision and
dental insurance), if any, as the Company shall make available to executive-level employees and in such employee benefit plans and fringe benefits as may be offered or made available by the Company to its employees. The Company shall not
unreasonably delay your ability to participate in such benefit plans and/or fringe benefit programs once such benefit plans and/or fringe benefits are available to employees. The Board reserves the right to change or terminate the Company’s
employee benefit plans and fringe benefits. Your participation in such employee benefit plans and fringe benefits, and the amount and nature of the benefits to which you shall be entitled thereunder or in connection therewith, shall be subject to
the terms and conditions of such employee benefit plans and fringe benefits. 

  

	 	•	 	 Expenses. Upon delivery of reasonable documentation, you will be entitled to reimbursement by the Company
during the term of your employment for reasonable travel, business development, and other business expenses incurred by you in the performance of your duties hereunder in accordance with the then-current policies and practices of the Company.

  

	 	•	 	 Initial Equity Award and Future Equity Awards. In connection with your commencement of employment in April
2020, the Company granted you a restricted stock award of 2,000,000 shares of the Company’s common stock (the “Shares”) pursuant to a restricted stock purchase agreement (the “Restricted Stock Purchase
Agreement”) between you and the Company which sets forth the terms of the award. 

 Lee D. Arnold, Ph.D. 

December 23, 2020 
  Page
 3
 
  

	 	 
Following your execution of this Agreement and subject to the approval of you and the Company’s Board of Directors, the Restricted Stock Purchase Agreement shall be amended, as deemed
necessary by the Company, to reflect the terms of this Agreement. In addition to the foregoing, you shall be eligible to receive grants of Company equity awards in the sole discretion of and subject to the approval of the Board or its Compensation
Committee. 

 Severance 
  

	 	•	 	 Termination Without Cause or Resignation for Good Reason following an Equity Financing. Following the
completion of an Equity Financing (which term is defined below in this Agreement), in the event that the Company terminates your employment other than due to: (i) Cause (which term is defined below in this Agreement), or (ii) your
death or disability, or in the event that you terminate your employment with the Company for Good Reason (which term is defined below in this Agreement), then, subject to the condition precedent of your execution and delivery of the Company’s
standard form general release to be delivered to you at the time of your termination, which release becomes irrevocable within sixty (60) days following your termination, you will be entitled to the following severance benefits (the “Non-CIC Severance Benefits”): 

  

	 	(i)	 your Base Salary for a period of nine (9) months following your termination of employment (such applicable
period, the “Severance Period”), which amount shall be paid in equal installments on the Company’s regular payroll schedule and will be subject to applicable tax withholdings over the period outlined above following the date of
your termination of employment; provided, however, that no payments will be made prior to the sixtieth (60th) day following your termination of employment. On the sixtieth (60th) day following your termination of employment, the Company will pay you in a lump sum the Base Salary that you would have received on or prior to such date under the original schedule but for the
delay while waiting for the sixtieth (60th) day in compliance with Section 409A (as defined below) and the effectiveness of the release, with the balance of the Base Salary being paid as originally scheduled. For such purposes, your final Base
Salary will be calculated at the rate in effect as of the effective date of termination of your employment and prior to giving effect to any reduction in Base Salary that would give rise to your right to resign for Good Reason;

  

	 	(ii)	 if you are eligible for and timely elect to continue your health insurance coverage under the Company’s
group health plans under the Consolidated Omnibus Budget Reconciliation Act of 1985 or the state equivalent (“COBRA”) following your termination date, the Company will pay the COBRA group health insurance premiums for you and your
eligible dependents until the earliest of (A) the close of the Severance Period, (B) the expiration of your eligibility for the continuation coverage under COBRA, or (C) the date when you become eligible for substantially equivalent
health insurance coverage in connection with new employment or self-employment. For purposes of this Section, references to COBRA premiums shall not include any amounts payable by you under a Section 125 health care reimbursement plan under the
Internal Revenue Code of 1986, as amended (the “Code”). Notwithstanding the foregoing, if at any time the Company determines, in its sole discretion, that it cannot pay the COBRA premiums without potentially incurring financial
costs or penalties under applicable law (including, without limitation, Section 2716 of the Public Health Service Act), then regardless of whether you elect continued health coverage under COBRA, and in lieu of providing the COBRA premiums, the
Company will instead pay you on the last day of each remaining month of the Severance Period, a fully taxable cash payment equal to the COBRA premiums for that month, subject to applicable tax

 Lee D. Arnold, Ph.D. 

December 23, 2020 
  Page
 4
 
  

	 	
withholdings (such amount, the “Health Care Benefit Payment”). The Health Care Benefit Payment shall be paid in monthly installments on the same schedule that the COBRA premiums
would otherwise have been paid and shall be equal to the amount that the Company would have otherwise paid for COBRA premiums, and shall be paid until the earlier of (i) expiration of the Severance Period or (ii) the date when you become
eligible for substantially equivalent health insurance coverage in connection with new employment or self-employment; 

  

	 	(iii)	 the vesting of all outstanding equity awards held by you shall be accelerated so that the amount of shares
vested under such equity award shall equal that number of shares which would have been vested if you had continued to render services to the Company through the Severance Period; and 

 

	 	(iv)	 outplacement assistance, in duration and amounts that are determined by the Company to be reasonable in its
sole discretion. 

  

	 	•	 	 Termination Without Cause or Resignation for Good Reason During a Change in Control Period. In the event
that the Company terminates your employment other than due to: (i) Cause, or (ii) your death or disability, or you terminate your employment with the Company for Good Reason, in each case at any time during the Change in Control Period
(which term is defined below in this Agreement) then, subject to the condition precedent of your execution and delivery of the Company’s standard form general release to be delivered to you at the time of your termination, which release becomes
irrevocable within sixty (60) days following your termination, you will be entitled to the following severance benefits (the “CIC Severance Benefits”) in lieu of any Non-CIC Severance
Benefits (and for the avoidance of doubt: (x) in no event will you be entitled to both the Non-CIC Severance Benefits and the CIC Severance Benefits, and (y) if the Company has commenced providing
the Non-CIC Severance Benefits to you prior to the date that you become eligible to receive the CIC Severance Benefits, the Non-CIC Severance Benefits previously
provided to you (or your beneficiaries or estate, as applicable) shall reduce the CIC Severance Benefits provided below): 

  

	 	(i)	 your Base Salary for a period of nine (9) months following your termination of employment (such period,
the “CIC Severance Period”), which amount shall be paid in equal installments on the Company’s regular payroll schedule and will be subject to applicable tax withholdings over the period outlined above following the date of
your termination of employment; provided, however, that no payments will be made prior to the sixtieth (60th) day following your termination of employment. On the sixtieth (60th) day following your termination of employment, the Company will pay you in a lump sum the Base Salary that you would have received on or prior to such date under the original schedule but for the
delay while waiting for the sixtieth (60th) day in compliance with Section 409A (as defined below) and the effectiveness of the release, with the balance of the Base Salary being paid as originally scheduled. For such purposes, your final Base
Salary will be calculated at the rate in effect as of the effective date of termination of your employment with the Company and prior to giving effect to any reduction in Base Salary that would give rise to your right to resign for Good Reason;

  

	 	(ii)	 a lump sum payment in an amount equal to your target annual bonus for the Company’s then-current fiscal
year, which payment shall be paid on the Company’s first standard payroll date following the later of (A) the date that is sixty (60) days following your date of termination, but in no event more than seventy-five (75) days
thereafter, or (B) the date of the Change in Control; 

 Lee D. Arnold, Ph.D. 

December 23, 2020 
  Page
 5
 
  

	 	(iii)	 if you are eligible for and timely elect to continue your health insurance coverage under the Company’s
group health plans under COBRA following your termination date, the Company will pay the COBRA group health insurance premiums for you and your eligible dependents until the earliest of (A) the close of the CIC Severance Period, (B) the
expiration of your eligibility for the continuation coverage under COBRA, or (C) the date when you become eligible for substantially equivalent health insurance coverage in connection with new employment or self-employment. For purposes of this
Section, references to COBRA premiums shall not include any amounts payable by you under a Section 125 health care reimbursement plan under the Code. Notwithstanding the foregoing, if at any time the Company determines, in its sole discretion,
that it cannot pay the COBRA premiums without potentially incurring financial costs or penalties under applicable law (including, without limitation, Section 2716 of the Public Health Service Act), then regardless of whether you elect continued
health coverage under COBRA, and in lieu of providing the COBRA premiums, the Company will instead pay you on the last day of each remaining month of the CIC Severance Period, a fully taxable cash payment equal to the Health Care Benefit Payment.
The Health Care Benefit Payment shall be paid in monthly installments on the same schedule that the COBRA premiums would otherwise have been paid and shall be equal to the amount that the Company would have otherwise paid for COBRA premiums, and
shall be paid until the earlier of (i) expiration of the CIC Severance Period or (ii) the date when you become eligible for substantially equivalent health insurance coverage in connection with new employment or self-employment;

  

	 	(iv)	 If such termination is due to the Company terminating your employment for any reason (other than Cause or due
to your death or disability) or your termination of your employment with the Company for Good Reason, then the vesting of all outstanding equity awards held by you shall be accelerated on the later of (A) the date of your termination or
(B) the date of such Change in Control, so that all such equity awards shall be deemed to be fully vested. In addition, subject to the terms of the Company’s equity plan, any such equity awards that are stock options may be exercised by
you (or your legal guardian or legal representative) until the latest of (x) three (3) months after the date of your termination of employment (y) with respect to any portion of such equity awards that become exercisable on the date of a
Change in Control pursuant to this clause (iv), three (3) months after the date of the Change in Control, or (z) such longer period as may be specified in the applicable equity award agreement; provided, however, that in no event shall any
equity award that is a stock option remain exercisable beyond the original outside expiration date of such equity award; and 

  

	 	(v)	 outplacement assistance, in duration and amounts that are determined by the Company to be reasonable in its
sole discretion. 

 Certain Definitions. 

For purposes of this Agreement, the following definitions shall be applicable: 

“Cause” shall mean any one or more of the following: (i) your intentional commission of an act, or intentional failure to
act, that materially injures the business of the Company; provided, however, that in no event shall any business judgment made in good faith by you and within your defined scope of authority constitute a basis for termination for Cause
under this Agreement; (ii) your intentional refusal or intentional failure to act in accordance with any lawful and proper direction or order of the Board or the Supervising Officer; (iii) your material breach of your fiduciary, statutory,
contractual, or common law duties to the 

 Lee D. Arnold, Ph.D. 

December 23, 2020 
  Page
 6
 
  

 
Company (including any material breach of this Agreement, the Proprietary Rights Agreement (as defined below), or the Company’s written policies); (iv) your indictment for or conviction of
any felony or any crime involving dishonesty; or (v) your participation in any fraud or other act of willful misconduct against the Company; provided, however, that in the event that any of the foregoing events is reasonably
capable of being cured, the Company shall provide written notice to you describing the nature of such event and you shall thereafter have twenty (20) days to cure such event. 

“Change in Control” shall mean (1) a sale of all or substantially all of the Company’s assets other than to an
Excluded Entity, (2) a merger, consolidation or other capital reorganization or business combination transaction of the Company with or into another corporation, limited liability company or other entity other than an Excluded Entity, or
(3) the consummation of a transaction, or series of related transactions, in which any “person” (as such term is used in Sections 13(d) and 14(d) of the Exchange Act) becomes the “beneficial owner” (as defined in Rule 13d-3 of the Exchange Act), directly or indirectly, of all of the Company’s then outstanding voting securities. Notwithstanding the foregoing, a transaction shall not constitute a Change of Control if its
purpose is to (A) change the jurisdiction of the Company’s incorporation, (B) create a holding company that will be owned in substantially the same proportions by the persons who hold the Company’s securities immediately before
such transaction, or (C) obtain funding for the Company in a financing that is approved by the Company’s Board of Directors. An “Excluded Entity” means a corporation, limited liability company or other entity of which the
holders of voting capital stock of the Company outstanding immediately prior to such transaction are the direct or indirect holders of voting securities representing at least a majority of the votes entitled to be cast by all of such
corporation’s, limited liability company’s or other entity’s voting securities outstanding immediately after such transaction. As used in this Agreement, the consummation of (i) a transaction or series of related transactions in
which any “person” or “group” (within the meaning of Section 13(d) and 14(d) of the Securities Exchange Act of 1934, as amended), becomes the “beneficial owner” (as defined in Rule
13d-3 under the Securities Exchange Act of 1934, as amended), directly or indirectly, of more than 50% of the outstanding voting securities of the Company having the right to vote for the election of members
of the Company’s board of directors, (ii) any reorganization, merger or consolidation of the Company, other than a transaction or series of related transactions in which the holders of the voting securities of the Company outstanding
immediately prior to such transaction or series of related transactions retain, immediately after such transaction or series of related transactions, at least a majority of the total voting power represented by the outstanding voting securities of
the Company or such other surviving or resulting entity or (iii) a sale, lease or other disposition of all or substantially all of the assets of the Company; provided, however, that following the Company’s IPO, “Change in
Control” shall have the meaning described in the Company’s stock plan adopted by the Company in connection with the Company’s IPO. 

“Change in Control Period” means the three (3) months prior to or within one (1) year after such Change in Control.

 “Equity Financing” means the consummation of a bona fide transaction or series of transactions with the principal
purpose of raising capital, pursuant to which the Company issues and sells in excess of $10,000,000 of preferred stock at a fixed valuation, including but not limited to, a pre-money or post-money valuation.

 “Good Reason” means any one or more of the following: (i) a material diminution in the nature or scope of your
duties; (ii) a material reduction in your Base Salary (other than as part of a reduction in the base salaries of all or substantially all other senior executives of the Company that is in the same proportion as the reduction in your Base
Salary); and (iii) the permanent, non-voluntary relocation of your principal place of employment with the Company to a location that increases your one-way
commuting distance by more than fifty (50) miles as compared to your then-current principal place of employment immediately 

 Lee D. Arnold, Ph.D. 

December 23, 2020 
  Page
 7
 
  

 
prior to such relocation. In order for you to resign for Good Reason, each of the following requirements must be met: (A) you much provide written notice to the Board or the Supervising
Officer within sixty (60) calendar days after the first occurrence of the event giving rise to Good Reason setting forth the basis for your resignation; (B) you must allow the Company at least twenty (20) days from receipt of such
written notice from you sufficiently describing such alleged Good Reason to cure such event; (C) such event must not be cured by the Company within such twenty (20) day period; and (D) you must resign for Good Reason not later than
sixty (60) days after the expiration of the foregoing cure period. 
 “IPO” means the Company’s initial public
offering of shares of its common stock pursuant to an effective Registration Statement on Form S-1. 

Withholding Taxes 
 All payments
and benefits described in this Agreement or that you may otherwise be entitled or eligible to receive as a result of your employment with the Company will be subject to applicable federal, state and local tax withholdings. 

409A Compliance 
 It is intended
that all of the severance benefits and other payments payable under this Agreement satisfy, to the greatest extent possible, the exemptions from the application of Section 409A of the Code (the
“Section 409A”), provided under Treasury Regulations 1.409A 1(b)(4), 1.409A 1(b)(5) and 1.409A 1(b)(9), and this Agreement will be construed to the greatest extent possible as consistent with those provisions, and
to the extent not so exempt, this Agreement (and any definitions hereunder) will be construed in a manner that complies with Section 409A. In furtherance of the foregoing, the severance payments payable under the heading
“Severance” shall be paid no later than the last date permitted in order to satisfy the exemption from Section 409A under Treasury Regulations 1.409A 1(b)(4). For purposes of Section 409A (including, without limitation,
for purposes of Treasury Regulation Section 1.409A 2(b)(2)(iii)), your right to receive any installment payments under this Agreement (whether severance payments, reimbursements or otherwise) shall be treated as a right to receive a series of
separate payments and, accordingly, each installment payment hereunder shall at all times be considered a separate and distinct payment. Notwithstanding any provision to the contrary in this Agreement, to the extent any payments to you pursuant to
this Agreement constitute “nonqualified deferred compensation” subject to Section 409A of the Code or are intended to be exempt from Section 409A of the Code pursuant to Treasury Regulation
Section 1.409A-1(b)(9)(iii), then, to the extent required by Section 409A of the Code or to satisfy such exception, no amount shall be payable pursuant to such sections unless your termination of
employment constitutes a “separation from service” with the Company (as such term is defined in Treasury Regulation Section 1.409A-1(h) and any successor provision thereto) (a
“Separation from Service”). Notwithstanding any provision to the contrary in this Agreement, if you are deemed by the Company at the time of your Separation from Service under Section 409A to be a “specified employee”
for purposes of Section 409A(a)(2)(B)(i), and if any of the payments upon Separation from Service set forth herein and/or under any other agreement with the Company are deemed to be “deferred compensation”, then to the extent delayed
commencement of any portion of such payments is required in order to avoid a prohibited distribution under Section 409A(a)(2)(B)(i) and the related adverse taxation under Section 409A, such payments shall not be provided to you prior to
the earliest of (i) the expiration of the six-month and one day period measured from the date of your Separation from Service with the Company, or (ii) such earlier date as permitted under
Section 409A without the imposition of adverse taxation. Upon the first business day following the expiration of such applicable Section 409A(a)(2)(B)(i) period, all payments deferred pursuant to this paragraph shall be paid in a lump sum
to you, and any remaining payments due shall be paid as otherwise provided herein or in the applicable agreement. No interest shall be due on any amounts so 

 Lee D. Arnold, Ph.D. 

December 23, 2020 
  Page
 8
 
  

 
deferred. If the Company determines that any severance benefits provided under this Agreement constitute “nonqualified deferred compensation” under Section 409A, for purposes of
determining the schedule for payment of the severance benefits, any such severance benefits shall not be paid, or in the case of installments shall not commence payment, until the sixtieth (60th) day following the Separation from Service or other
applicable payment event. In addition to the above, to the extent required to comply with Section 409A and the applicable regulations and guidance issued thereunder, if the applicable deadline for you to execute (and not revoke) the applicable
release spans two calendar years, payment of the applicable severance benefits shall not commence until the beginning of the second calendar year. To the extent required to avoid accelerated taxation and/or tax penalties under Section 409A,
amounts reimbursable to you under this Agreement shall be paid to you on or before the last day of the year following the year in which the expense was incurred and the amount of expenses eligible for reimbursement (and in-kind benefits provided to you) during any one year may not effect amounts reimbursable or provided in any subsequent year. The Company makes no representation that any or all of the payments described in this
Agreement will be exempt from or comply with Section 409A and makes no undertaking to preclude Section 409A from applying to any such payment. Notwithstanding the foregoing if a Change in Control would give rise to a payment or settlement
event with respect to any payment or benefit that constitutes “nonqualified deferred compensation,” the transaction or event constituting the Change in Control must also constitute a “change in control event” (as defined in
Treasury Regulation §1.409A-3(i)(5)) in order to give rise to the payment or settlement event for such payment or benefit, to the extent required by Section 409A. 

Nondisclosure and Developments 
 As
a condition of your employment, you shall sign the Company’s standard employee Confidential Information and Invention Assignment Agreement (the “Proprietary Rights Agreement”), which you executed on April 6, 2020 and it
remains in full force and effect. 
 No Conflicting Obligation 

You hereby represent and warrant that as of April 6, 2020 and as of the execution and delivery of this Agreement, the performance by you
of any or all of the terms of this Agreement and the performance by you of your duties as an employee of the Company do not and will not breach or contravene (i) any agreement or contract (including, without limitation, any employment or
consulting agreement, any agreement not to compete or any confidentiality or nondisclosure agreement) to which you are or may become a party on or at any time after your commencement of employment or (ii) any obligation you may otherwise have
under applicable law to any former employer or to any person to whom you have provided, provide or will provide consulting services. You hereby further represent and warrant to the Company that, prior to the date your employment commenced, you
provided to the Company a copy of any and all potentially conflicting agreements for the Company’s review. 
 Defend Trade Secrets Act Notice of
Immunity Rights 
 You acknowledge that the Company has provided you with the following notice of immunity rights in compliance with
the requirements of the Defend Trade Secrets Act: (i) you shall not be held criminally or civilly liable under any Federal or State trade secret law for the disclosure of proprietary information that is made in confidence to a Federal, State,
or local government official or to an attorney solely for the purpose of reporting or investigating a suspected violation of law; (ii) you shall not be held criminally or civilly liable under any Federal or State trade secret law for the
disclosure of proprietary information that is made in a complaint or other document filed in a lawsuit or other proceeding, if such filing is made under seal; and (iii) if you file a lawsuit for retaliation by the Company for reporting a
suspected violation of law, you may disclose the proprietary information to your attorney and use the proprietary information in the court proceeding, if you file any document containing the proprietary information under seal, and do not disclose
the proprietary information, except pursuant to court order. 

 Lee D. Arnold, Ph.D. 

December 23, 2020 
  Page
 9
 
  

 Termination 

You acknowledge that the employment relationship between the Company and you is at-will, meaning that
the employment relationship may be terminated by the Company or you for any reason or for no reason. Either party may terminate your employment with the Company at any time and for any or no reason upon thirty (30) days prior written notice;
provided that the Company may terminate you for Cause and you may resign for Good Reason (subject to the process specified within the definition) at any time upon written notice. 

Regardless of the reason your employment with the Company terminates, you will continue to comply with the Proprietary Rights Agreement
contemplated hereby. 
 Work Eligibility 

You agree that prior to the commencement of employment, you will provide the Company with sufficient documentation to demonstrate your
eligibility to work in the United States and, at the request of the Company, shall provide any additional documentation requested by the Company to demonstrate your eligibility to work in the United States. 

Governing Law 
 This Agreement
shall be governed by and construed in accordance with the internal substantive laws of the State of California. 
 Dispute Resolution 

To ensure the rapid and economical resolution of disputes that may arise in connection with your employment with the Company, you and the
Company agree that any and all disputes, claims, or causes of action, in law or equity, including but not limited to statutory claims, arising from or relating to the enforcement, breach, performance, or interpretation of this Agreement, your
employment with the Company, or the termination of your employment from the Company, will be resolved pursuant to the Federal Arbitration Act, 9 U.S.C. §1-16, and to the fullest extent permitted by law,
by final, binding and confidential arbitration conducted in San Francisco, California by JAMS, Inc. (“JAMS”) or its successors, under JAMS’ then applicable rules and procedures for employment disputes (which can be found at
http://www.jamsadr.com/rules-clauses/, and which will be provided to you on request); provided that the arbitrator shall: (a) have the authority to compel adequate discovery for the resolution of the dispute and to award such relief as
would otherwise be permitted by law; and (b) issue a written arbitration decision including the arbitrator’s essential findings and conclusions and a statement of the award. You and the Company shall be entitled to all rights and remedies
that either would be entitled to pursue in a court of law. BOTH YOU AND THE COMPANY ACKNOWLEDGE THAT BY AGREEING TO THIS ARBITRATION PROCEDURE, YOU AND THE COMPANY WAIVE THE RIGHT TO RESOLVE ANY SUCH DISPUTE THROUGH A TRIAL BY JURY OR JUDGE OR
ADMINISTRATIVE PROCEEDING. The Company shall pay all filing fees in excess of those which would be required if the dispute were decided in a court of law, and shall pay the arbitrator’s fee. Nothing in this Agreement is intended to prevent
either the Company or you from obtaining injunctive relief in court to prevent irreparable harm pending the conclusion of any such arbitration. This section is intended to be the exclusive 

 Lee D. Arnold, Ph.D. 

December 23, 2020 
  Page
 10
 
  

 
method for resolving any and all claims by the parties against each other for payment of damages under this Agreement or relating to your employment; provided, however, that you
shall retain the right to file administrative charges with or seek relief through any government agency of competent jurisdiction, and to participate in any government investigation, including but not limited to (i) claims for workers’
compensation, state disability insurance or unemployment insurance; (ii) claims for unpaid wages or waiting time penalties brought before the California Division of Labor Standards Enforcement (or any similar agency in any applicable
jurisdiction other than California); provided, however, that any appeal from an award or from denial of an award of wages and/or waiting time penalties shall be arbitrated pursuant to the terms of this Agreement; and (iii) claims
for administrative relief from the United States Equal Employment Opportunity Commission and/or the California Department of Fair Employment and Housing (or any similar agency in any applicable jurisdiction other than California); provided,
further, that you shall not be entitled to obtain any monetary relief through such agencies other than workers’ compensation benefits or unemployment insurance benefits. 

Entire Agreement; Amendment 
 This
Agreement (together with the Proprietary Rights Agreement contemplated hereby) sets forth the sole and entire agreement and understanding between the Company and you with respect to the specific matters contemplated and addressed hereby and thereby.
No prior agreement, whether written or oral, shall be construed to change or affect the operation of this Agreement in accordance with its terms, and any provision of any such prior agreement, which conflicts with or contradicts any provision of
this Agreement, is hereby revoked and superseded. Any prior agreement, if any, you may have with the Company regarding your employment, whether written or oral, is hereby, and without any further action on your part or the Company’s,
terminated, revoked and superseded by this Agreement. This Agreement may be amended or terminated only by a written instrument executed both by you and the Company. 

Notices 
 Any notices provided must
be in writing and will be deemed effective upon the earlier of personal delivery (including personal delivery by fax) or the next day after sending by overnight carrier, to the Company at its primary office location and to you at the address as
listed on the Company payroll. 
 Severability 

Whenever possible, each provision of this Agreement will be interpreted in such manner as to be effective and valid under applicable law, but
if any provision of this Agreement is held to be invalid, illegal or unenforceable in any respect under any applicable law or rule in any jurisdiction, such invalidity, illegality or unenforceability will not affect any other provision or any other
jurisdiction, but this Agreement will be reformed, construed and enforced in such jurisdiction to the extent possible in keeping with the intent of the Parties. 

 Lee D. Arnold, Ph.D. 

December 23, 2020 
  Page
 11
 
  

 Waiver 

Any waiver of any breach of any provisions of this Agreement must be in writing to be effective, and it shall not thereby be deemed to have
waived any preceding or succeeding breach of the same or any other provision of this Agreement. 
 Counterparts 

This Agreement may be executed in separate counterparts, any one of which need not contain signatures of more than one party, but both of which
taken together will constitute one and the same Agreement. 
 Headings 

The headings of the sections and paragraphs hereof are inserted for convenience only and shall not be deemed to constitute a part hereof nor to
affect the meaning thereof. 
 Indemnification and Director’s and Officer’s Insurance 

The Company will indemnify you to the fullest extent permitted by the laws of the State of Delaware, as in effect at the time of the subject
act or omission, and you shall be entitled to the protection of any insurance policies the Company may elect to maintain generally for the benefit of its directors and officers. 

Successors and Assigns 
 This
Agreement is intended to bind and inure to the benefit of and be enforceable by you and the Company, and your respective successors, assigns, heirs, executors and administrators, except that you may not assign any of your duties hereunder and you
may not assign any of your rights hereunder without the written consent of the Company, which shall not be withheld unreasonably. 

[Signature Page Follows] 

 Lee D. Arnold, Ph.D. 

December 23, 2020 
  Page
 12
 
  

 Please acknowledge your acceptance of the terms of this Agreement by signing below and
returning a copy to me. 
  

			
	Sincerely,
	
	PARDES BIOSCIENCES, INC.
		
	By:	 	/s/ Uri A. Lopatin, M.D.
		 	Name: Uri A. Lopatin, M.D.
		 	Title: President and CEO

 Accepted and Agreed: 

I hereby acknowledge that I have had a full and adequate 

opportunity to read, understand and discuss the terms and 

conditions contained in this Agreement prior to signing hereunder. 
  

			
	/s/ Lee D. Arnold, Ph.D.
	Lee D. Arnold, Ph.D.

			
		
	Date:	 	12/28/2020

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00338-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00338-of-00352.parquet"}]]