Document:

Exhibit 4.4

 

THE SECURITY
(OR ITS PREDECESSOR) EVIDENCED BY THIS CERTIFICATE WAS ORIGINALLY ISSUED IN A
TRANSACTION EXEMPT FROM REGISTRATION UNDER SECTION 5 OF THE U.S. SECURITIES ACT
OF 1933, AND THE SECURITY EVIDENCED BY THIS CERTIFICATE MAY NOT BE OFFERED,
SOLD, PLEDGED OR OTHERWISE TRANSFERRED IN THE ABSENCE OF REGISTRATION OR AN
APPLICABLE EXEMPTION FROM THE SECURITIES ACT. 
EACH PURCHASER OF THE SECURITY EVIDENCED BY THIS CERTIFICATE (1) BY ITS
ACQUISITION OF THE SECURITY REPRESENTS THAT (A) IT IS A “QUALIFIED
INSTITUTIONAL BUYER (AS DEFINED IN RULE 144A UNDER THE SECURITIES ACT) OR (B)
IT IS NOT A U.S. PERSON AND IS ACQUIRING THE SECURITY EVIDENCED BY THIS
CERTIFICATE IN AN OFFSHORE TRANSACTION IN COMPLIANCE WITH REGULATION S UNDER
THE SECURITIES ACT, AND (2) IS HEREBY NOTIFIED THAT THE SELLER MAY BE RELYING
ON THE EXEMPTION FROM THE PROVISIONS OF SECTION 5 OF THE SECURITIES ACT
PROVIDED BY RULE 144A OR ANOTHER EXEMPTION UNDER THE SECURITIES ACT.  THE HOLDER OF THE SECURITY EVIDENCED BY THIS
CERTIFICATE AGREES FOR THE BENEFIT OF THE ISSUER AND THE GUARANTORS THAT (X)
THIS SECURITY MAY BE RESOLD, PLEDGED OR OTHERWISE TRANSFERRED ONLY (1)(A) TO A
PERSON WHO THE SELLER REASONABLY BELIEVES IS A QUALIFIED INSTITUTIONAL BUYER
(AS DEFINED IN RULE 144A UNDER THE SECURITIES ACT) IN A TRANSACTION MEETING THE
REQUIREMENTS OF RULE 144A, (B) IN A TRANSACTION MEETING THE REQUIREMENTS OF
RULE 144 UNDER THE SECURITIES ACT, IF AVAILABLE, OR ANOTHER AVAILABLE EXEMPTION
UNDER THE SECURITIES ACT, (C) OUTSIDE THE UNITED STATES TO A PERSON THAT IS NOT
A U.S. PERSON (AS DEFINED IN RULE 902 UNDER THE SECURITIES ACT) IN A
TRANSACTION MEETING THE REQUIREMENTS OF REGULATION S UNDER THE SECURITIES ACT,
(D) TO AN ACCREDITED INVESTOR (WITHIN THE MEANING OF RULE 501(a)(1), (2), (3), OR
(7) UNDER THE SECURITIES ACT) (AN “INSTITUTIONAL ACCREDITED INVESTOR”) THAT IS
PURCHASING AT LEAST $250,000 OF NOTES FOR ITS OWN ACCOUNT OR FOR THE ACCOUNT OF
AN INSTITUTIONAL ACCREDITED INVESTOR (AND BASED UPON AN OPINION OF COUNSEL IF
THE ISSUER SO REQUESTS), (2) TO THE ISSUER OR ANY OF ITS SUBSIDIARIES OR (3)
UNDER AN EFFECTIVE REGISTRATION STATEMENT AND, IN EACH CASE, IN COMPLIANCE WITH
ANY APPLICABLE SECURITIES LAWS OF ANY STATE OF THE UNITED STATES OR ANY OTHER
APPLICABLE JURISDICTION AND (Y) THE HOLDER WILL, AND EACH SUBSEQUENT HOLDER IS
REQUIRED TO, NOTIFY ANY PURCHASER FROM IT OF THE SECURITY EVIDENCED BY THIS
CERTIFICATE OF THE RESALE RESTRICTIONS DESCRIBED IN (X) ABOVE.  IN CONNECTION WITH ANY TRANSFER OF THIS
SECURITY WITHIN TWO YEARS AFTER THE ORIGINAL ISSUANCE OF THIS SECURITY OR IF
THE PROPOSED TRANSFEREE IS AN INSTITUTIONAL ACCREDITED INVESTOR, THE HOLDER
MUST, PRIOR TO SUCH TRANSFER, FURNISH TO THE TRUSTEE AND THE ISSUER SUCH
CERTIFICATIONS, LEGAL OPINIONS OR OTHER INFORMATION AS EITHER OF THEM MAY
REASONABLY REQUIRE TO CONFIRM THAT SUCH TRANSFER IS BEING MADE PURSUANT TO AN
EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION
REQUIREMENTS OF THE SECURITIES ACT.

 

THIS GLOBAL
NOTE IS A TEMPORARY GLOBAL NOTE FOR PURPOSES OF REGULATION S UNDER THE
UNITED STATES SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”).  NEITHER
THIS TEMPORARY GLOBAL NOTE

 

 

NOR ANY
INTEREST HEREIN MAY BE OFFERED, SOLD OR DELIVERED, EXCEPT AS PERMITTED UNDER
THE INDENTURE REFERRED TO BELOW.

 

NO BENEFICIAL
OWNERS OF THIS TEMPORARY GLOBAL NOTE SHALL BE ENTITLED TO RECEIVE PAYMENT OF
PRINCIPAL OR INTEREST HEREON UNLESS THE REQUIRED CERTIFICATIONS HAVE BEEN
DELIVERED PURSUANT TO THE TERMS OF THE INDENTURE.

 

THIS NOTE IS A GLOBAL NOTE WITHIN THE MEANING OF THE INDENTURE
HEREINAFTER REFERRED TO AND IS REGISTERED IN THE NAME OF A DEPOSITORY OR A
NOMINEE OF A DEPOSITORY OR A SUCCESSOR DEPOSITORY.  THIS NOTE IS NOT EXCHANGEABLE FOR NOTES REGISTERED IN THE NAME OF
A PERSON OTHER THAN THE DEPOSITORY OR ITS NOMINEE EXCEPT IN THE LIMITED CIRCUMSTANCES
DESCRIBED IN THE INDENTURE, AND NO TRANSFER OF THIS NOTE (OTHER THAN A TRANSFER
OF THIS NOTE AS A WHOLE BY THE DEPOSITORY TO A NOMINEE OF THE DEPOSITORY OR BY
A NOMINEE OF THE DEPOSITORY TO THE DEPOSITORY OR ANOTHER NOMINEE OF THE
DEPOSITORY) MAY BE REGISTERED EXCEPT IN THE LIMITED CIRCUMSTANCES DESCRIBED IN
THE INDENTURE.

 

UNLESS THIS CERTIFICATE IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF
THE DEPOSITORY TRUST COMPANY, A NEW YORK CORPORATION (“DTC”), TO THE ISSUER OR
ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY
CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR IN SUCH OTHER
NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC (AND ANY PAYMENT IS
MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED
REPRESENTATIVE OF DTC), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR
OTHERWISE BY OR TO ANY PERSON IS WRONGFUL INASMUCH AS THE REGISTERED OWNER
HEREOF, CEDE & CO., HAS AN INTEREST HEREIN.

 

TRANSFERS OF THIS GLOBAL NOTE SHALL BE LIMITED TO TRANSFERS IN WHOLE,
BUT NOT IN PART, TO NOMINEES OF CEDE & CO. OR TO A SUCCESSOR THEREOF OR
SUCH SUCCESSOR’S NOMINEE AND TRANSFERS OF PORTIONS OF THIS GLOBAL NOTE SHALL BE
LIMITED TO TRANSFERS MADE IN ACCORDANCE WITH THE RESTRICTIONS SET FORTH IN
SECTION 2.16 OF THE INDENTURE.

 

 

[FACE OF NOTE]

 

CURATIVE HEALTH SERVICES, INC.

[   ]% Senior Notes 2011

 

	
   

  	
   

  	
  CUSIP No.

  	
   

  
	
  No.

  	
   

  	
  $

  	
   

  

 

CURATIVE
HEALTH SERVICES, INC., a Minnesota corporation (the “Issuer”), for value received
promise to pay to
[              ]
or its registered assigns, the principal sum of
                         
or such other amount as is provided in a schedule attached hereto on
[             ],
2011.

 

Interest
Payment Dates: 
[                  ]
and [                  ],
commencing
[                  ],
2004.

 

Record
Dates: 
[                  ]
and
[                  ].

 

Reference is
made to the further provisions of this Note contained herein, which will for
all purposes have the same effect as if set forth at this place.

 

 

IN WITNESS
WHEREOF, the Issuer has caused this Note to be signed manually or by facsimile
by its duly authorized officer.

 

Dated: 
[             ],
2004

 

	
   

  	
  CURATIVE
  HEALTH SERVICES, INC., as Issuer

  
	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
  By:

  	
   

  	
   

  
	
   

  	
   

  	
  Name:

  
	
   

  	
   

  	
  Title:

  
					

 

 

FORM OF
TRUSTEE’S CERTIFICATE OF AUTHENTICATION

 

This is one of
the [  ]% Senior Notes due 2011 described in the within-mentioned
Indenture.

 

Dated: 
[                  ],
2004

 

	
   

  	
  WELLS FARGO
  BANK, N.A., as Trustee

  
	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
  By:

  	
   

  	
   

  
	
   

  	
   

  	
  Authorized Signatory

  
					

 

 

[REVERSE OF NOTE]

 

[   ]% Senior Notes due 2011

 

Capitalized
terms used herein shall have the meanings assigned to them in the Indenture
referred to below unless otherwise indicated.

 

SECTION
1.  Interest.  Curative Health Services, Inc., a Minnesota
corporation (the “Issuer”), promises to pay interest on the
principal amount of this Note at [   ]% per annum from
[                   ],
2004 until maturity.  The Issuer will
pay interest semi-annually on
[                   ]
and [                   ]
of each year, or if any such day is not a Business Day, on the next succeeding
Business Day (each an “Interest Payment Date”), commencing
[                   ],
2004.  Interest on the Notes will accrue
from the most recent date to which interest has been paid or, if no interest
has been paid, from the date of original issuance.  The Issuer shall pay interest (including post-petition interest
in any proceeding under any Bankruptcy Law) on overdue principal and premium,
if any, from time to time on demand to the extent lawful at the interest rate
applicable to the Notes; it shall pay interest (including post-petition
interest in any proceeding under any Bankruptcy Law) on overdue installments of
interest (without regard to any applicable grace periods) from time to time on
demand at the same rate to the extent lawful. 
Interest will be computed on the basis of a 360-day year of twelve
30-day months.

 

SECTION
2.  Method of Payment.  The Issuer will pay interest on the Notes to
the Persons who are registered Holders of Notes at the close of business on the
[              ]
or
[              ]
next preceding the Interest Payment Date, even if such Notes are canceled after
such record date and on or before such Interest Payment Date, except as
provided in Section 2.12 of the Indenture with respect to defaulted
interest.  The Notes will be issued in
denominations of $1,000 and integral multiples thereof.  The Issuer shall pay principal, premium, if
any, and interest on the Notes in such coin or currency of the United States of
America as at the time of payment is legal tender for payment of public and
private debts (“U.S. Legal Tender”). 
Principal, premium, if any, and interest on the Notes will be payable at
the office or agency of the Issuer maintained for such purpose except that, at
the option of the Issuer, the payment of interest may be made by check mailed
to the Holders of the Notes at their respective addresses set forth in the
register of Holders of Notes; provided that for Holders that have given
wire transfer instructions to the Issuer at least ten Business Days prior to
the applicable payment date, the Issuer will make all payments of principal,
premium and interest by wire transfer of immediately available funds to the accounts
specified by the Holders thereof.  Until
otherwise designated by the Issuer, the Issuer’s office or agency in New York
will be the office of the Trustee maintained for such purpose.

 

SECTION
3.  Paying Agent and Registrar.  Initially, Wells Fargo Bank, N.A., the
Trustee under the Indenture, will act as Paying Agent and Registrar.  The Issuer may change any Paying Agent or
Registrar without notice to any Holder. 
Except as provided in the Indenture, the Issuer or any of their Subsidiaries
may act in any such capacity.

 

SECTION 4.  Indenture.  The Issuer issued the Notes under an Indenture dated as of
[                   ],
2004 (“Indenture”)
by and among the Issuer, the Guarantors and the Trustee.  The terms of the Notes include those stated
in the Indenture and those made part of the Indenture by reference to the Trust
Indenture Act of 1939, as amended (15 U.S. Code §§ 77aaa-77bbbb) (the
“Trust
Indenture Act”).  The Notes
are subject to all such terms, and Holders are referred to the Indenture and
the Trust Indenture Act for a statement of such terms.

 

SECTION
5.  Optional Redemption.  Except as set forth in Section 6 hereof, the
Notes will not be redeemable at the Issuer’s option prior to
[                   ],
2008 (the “First Call Date”).  On
or

 

 

after the First Call Date, the Notes will be
subject to redemption at any time at the option of the Issuer, in whole or in
part, upon not less than 30 nor more than 60 days’ notice, at the redemption
prices (expressed as percentages of principal amount) set forth below plus accrued
and unpaid interest thereon, if any, to the applicable Redemption Date, if
redeemed during the twelve-month period beginning on
[                   ]
of the years indicated below:  

 

	
  Year

  	
   

  	
  Percentage

  	
   

  
	
   

  	
   

  	
   

  	
   

  
	
  2008

  	
   

  	
  [             ]

  	
  %

  
	
  2009

  	
   

  	
  [             ]

  	
  %

  
	
  2010

  	
   

  	
  100.000

  	
  %

  

 

SECTION
6.  Redemption with Proceeds from
Equity Offerings.  At any time prior
to
[             ],
2007, the Issuer may redeem at its option on any one or more occasions up to
35% of the aggregate principal amount of Notes issued under the Indenture with
the net cash proceeds of one or more Qualified Equity Offerings at a redemption
price equal to [   ]% of the principal amount of the Notes to be
redeemed, plus accrued and unpaid interest thereon, if any, to the Redemption
Date; provided
that (i) at least 65% of the aggregate principal amount of Notes issued under
the Indenture remains outstanding immediately after the occurrence of such
redemption and (ii) such redemption shall occur within 90 days of the date
of the closing of any such Qualified Equity Offering.

 

SECTION
7.  Notice of Redemption.  Notice of redemption will be mailed by first
class mail at least 30 days but not more than 60 days before the Redemption
Date to each Holder of Notes to be redeemed at its registered address.  Notes in denominations larger than $1,000
may be redeemed in part.  If any Note is
to be redeemed in part only, the notice of redemption that relates to such Note
shall state the portion of the principal amount thereof to be redeemed.  A new Note in principal amount equal to the
unredeemed portion thereof will be issued in the name of the Holder thereof
upon cancellation of the original Note. 
On and after the Redemption Date interest ceases to accrue on Notes or
portions thereof called for redemption.

 

SECTION
8.  No Mandatory Redemption.  For the avoidance of doubt, an
offer to purchase pursuant to Section 9 hereof shall not be deemed a
redemption.  The Issuer shall not be
required to make mandatory redemption payments with respect to the Notes.

 

SECTION 9.  Repurchase at Option of Holder.  Upon the occurrence of a Change
of Control, and subject to certain conditions set forth in the Indenture, the
Issuer will be required to offer to purchase all of the outstanding Notes at a
purchase price equal to 101% of the principal amount thereof, plus accrued and
unpaid interest, if any, thereon to the date of repurchase.

 

The Issuer is,
subject to certain conditions and exceptions, obligated to make an offer to
purchase Notes at 100% of their principal amount, plus accrued and unpaid interest,
if any, thereon to the date of repurchase, with certain net cash proceeds of
certain sales or other dispositions of assets in accordance with the Indenture.

 

SECTION
10.  Denominations, Transfer,
Exchange.  The Notes are in registered
form without coupons in denominations of $1,000 and integral multiples of
$1,000.  The transfer of Notes may be
registered and Notes may be exchanged as provided in the Indenture.  The Registrar and the Trustee may require a
Holder, among other things, to furnish appropriate endorsements and transfer
documents and the Issuer may require a Holder to pay any taxes and fees required
by law or permitted by the Indenture. 
The Issuer and the Registrar are not required to transfer or exchange
any Note selected for

 

 

redemption. 
Also, the Issuer and the Registrar are not required to transfer or
exchange any Notes for a period of 15 days before a selection of Notes to be redeemed.

 

SECTION
11.  Persons Deemed Owners.  The registered Holder of a Note may be
treated as its owner for all purposes.

 

SECTION
12.  Amendment, Supplement and Waiver.  Subject to certain exceptions, the Indenture
and the Notes may be amended or supplemented with the written consent of the
Holders of at least a majority in aggregate principal amount of the Notes then
outstanding, and any existing Default or compliance with any provision may be
waived with the consent of the Holders of a majority in aggregate principal
amount of the Notes then outstanding. 
Without notice to or consent of any Holder, the parties thereto may
amend or supplement the Indenture and the Notes to, among other things, cure
any ambiguity, defect or inconsistency in the Indenture, provide for
uncertificated Notes in addition to certificated Notes, comply with any requirements
of the SEC in connection with the qualification of the Indenture under the
Trust Indenture Act, or make any change that does not materially adversely affect
the rights of any Holder of a Note.

 

SECTION
13.  Defaults and Remedies.  If a Default occurs and is continuing, the
Trustee or the Holders of at least 25% in principal amount of the then
outstanding Notes generally may declare all the Notes to be due and payable
immediately.  Notwithstanding the foregoing,
in the case of a Default arising from certain events of bankruptcy or
insolvency as set forth in the Indenture, with respect to the Issuer, all outstanding
Notes will become due and payable without further action or notice.  Holders of the Notes may not enforce the
Indenture or the Notes except as provided in the Indenture.  Subject to certain limitations, Holders of a
majority in principal amount of the then outstanding Notes may direct the
Trustee in its exercise of any trust or power. 
The Trustee may withhold from Holders of the Notes notice of any
continuing Default (except a Default relating to the payment of principal or
interest, including an accelerated payment or the failure to make a payment on
the Change of Control Payment Date or the Net Proceeds Payment Date pursuant to
a Net Proceeds Offer, or a Default in complying with the provisions of Article
Five of the Indenture) if it determines that withholding notice is in their
interest.  The Holders of a majority in
aggregate principal amount of the Notes then outstanding, by notice to the
Trustee, may, on behalf of the Holders of all of the Notes, waive any existing
Default and its consequences under the Indenture, except a continuing Default
in the payment of interest on, or the principal of, or the premium on, the
Notes.

 

SECTION
14.  Restrictive Covenants.  The Indenture contains certain covenants
that, among other things, limit the ability of the Issuer and its Restricted
Subsidiaries to make restricted payments, to incur indebtedness, to create
liens, to sell assets, to permit restrictions on dividends and other payments
by Restricted Subsidiaries of the Issuer, to consolidate, merge or sell all or
substantially all of its assets or to engage in transactions with affiliates.  The limitations are subject to a number of
important qualifications and exceptions. 
The Issuer must annually report to the Trustee on compliance with such
limitations and other provisions in the Indenture.

 

SECTION
15.  No Recourse Against Others.  No director, officer, employee, incorporator,
stockholder, member or manager of the Issuer or any Guarantor shall have any
liability for any obligations of the Issuer under the Notes or the Indenture,
or of any Guarantor under its Note Guarantee or the Indenture or for any claim
based on, in respect of, or by reason of, such obligations or their
creation.  Each Holder of Notes, by
accepting a Note, waives and releases all such liability.  The waiver and release are part of the
consideration for issuance of the Notes.

 

 

SECTION
16.  Note Guarantees.  This Note will be entitled to the benefits
of certain Note Guarantees made for the benefit of the Holders.  Reference is hereby made to the Indenture
for a statement of the respective rights, limitations of rights, duties and
obligations thereunder of the Guarantors, the Trustee and the Holders.

 

SECTION
17.  Trustee Dealings with the Issuer.  Subject to certain terms, the Trustee under
the Indenture, in its individual or any other capacity, may become the owner or
pledgee of Notes and may otherwise deal with the Issuer, their Subsidiaries or
their respective Affiliates as if it were not the Trustee.

 

SECTION
18.  Authentication.  This Note shall not be valid until authenticated
by the manual signature of the Trustee or an authenticating agent.

 

SECTION
19.  Abbreviations.  Customary abbreviations may be used in the
name of a Holder or an assignee, such as: 
TEN COM (= tenants in common), TEN ENT (= tenants by the entirety), JT
TEN (= joint tenants with right of survivorship and not as tenants in common),
CUST (= Custodian), and U/G/M/A (= Uniform Gifts to Minors Act).

 

SECTION
20.  Additional Rights of Holders of
Restricted Global Notes and Restricted Definitive Notes.  Pursuant to, but subject to the exceptions
in, the Registration Rights Agreement, the Issuer and the Guarantors will be
obligated to use their commercially reasonable efforts to consummate an
exchange offer pursuant to which the Holder of this Note shall have the right
to exchange this Note for a [  ]% Senior Note due 2011 of the Issuer
which shall have been registered under the Securities Act, in like principal
amount and having terms identical in all material respects to this Note (except
that such note shall not be entitled to Additional Interest and shall not
contain terms with respect to transfer restrictions and the other rights under
the Registration Rights Agreement).  The
Holders shall be entitled to receive certain Additional Interest in the event
such exchange offer is not consummated or the Notes are not offered for resale
and upon certain other conditions, all pursuant to and in accordance with the
terms of the Registration Rights Agreement.

 

SECTION
21.  CUSIP and ISIN Numbers.  Pursuant to a recommendation promulgated by
the Committee on Uniform Security Identification Procedures, the Issuer has
caused CUSIP and ISIN numbers to be printed on the Notes and the Trustee may
use CUSIP or ISIN numbers in notices of redemption as a convenience to
Holders.  No representation is made as
to the accuracy of such numbers either as printed on the Notes or as contained
in any notice of redemption and reliance may be placed only on the other
identification numbers placed thereon.

 

SECTION
22.  Governing Law.  This Note shall be governed by, and construed in
accordance with, the laws of the State of New York.

 

The Issuer
will furnish to any Holder upon written request and without charge a copy of
the Indenture.

 

 

ASSIGNMENT FORM

 

	
  I or we
  assign and transfer this Note to

  
	
   

  
	
   

  
	
   

  
	
  (Print or
  type name, address and zip code of assignee or transferee)

  
	
   

  
	
   

  
	
  (Insert Social
  Security or other identifying number of assignee or transferee)

  

 

and irrevocably appoint
                                                                     
agent to transfer this Note on the books of the Issuer.  The agent may substitute another to act for
him.

 

	
  Dated:

  	
   

  	
   

  	
  Signed:

  	
   

  	
   

  
	
   

  	
   

  	
  (Sign exactly as name appears on

  the other side of this Note)

  
	
   

  	
   

  
	
   

  	
   

  
	
  Signature Guarantee:

  	
   

  	
   

  
	
   

  	
  Participant in a recognized Signature Guarantee Medallion Program (or
  other signature guarantor program reasonably acceptable to the Trustee)

  
									

 

In connection
with any transfer of this Note occurring prior to the date which is the date
following the second anniversary of the original issuance of this Note, the
undersigned confirms that it has not utilized any general solicitation or
general advertising in connection with the transfer and is making the transfer
pursuant to one of the following:

 

[Check One]

 

	
  (1)

  	
  o

  	
   

  	
  to the
  Issuer or a subsidiary thereof; or

  
	
   

  	
   

  	
   

  	
   

  
	
  (2)

  	
  o

  	
   

  	
  to a person
  who the transferor reasonably believes is a “qualified institutional buyer”
  pursuant to and in compliance with Rule 144A under the Securities Act of
  1933, as amended (the “Securities Act”); or

  
	
   

  	
   

  	
   

  	
   

  
	
  (3)

  	
  o

  	
   

  	
  to an
  institutional “accredited investor” (as defined in Rule 501(a)(1), (2), (3)
  or (7) under the Securities Act) that has furnished to the Trustee a signed
  letter containing certain representations and agreements (the form of which
  letter can be obtained from the Trustee); or

  
	
   

  	
   

  	
   

  	
   

  
	
  (4)

  	
  o

  	
   

  	
  outside the
  United States to a non-”U.S. person” as defined in Rule 902 of
  Regulation S under the Securities Act in compliance with Rule 904 of
  Regulation S under the Securities Act; or

  
	
   

  	
   

  	
   

  	
   

  
	
  (5)

  	
  o

  	
   

  	
  pursuant to
  the exemption from registration provided by Rule 144 under the Securities Act
  or pursuant to another exemption available under the Securities Act; or

  
	
   

  	
   

  	
   

  	
   

  
	
  (6)

  	
  o

  	
   

  	
  pursuant to
  an effective registration statement under the Securities Act.

  

 

 

and unless the
box below is checked, the undersigned confirms that such Note is not being transferred
to an “affiliate” of the Issuer as defined in Rule 144 under the Securities Act
(an “Affiliate”):

 

o    The transferee is an Affiliate
of the Issuer.

 

Unless one of
the foregoing items (1) through (6) is checked, the Trustee will refuse to
register any of the Notes evidenced by this certificate in the name of any
person other than the registered Holder thereof; provided, however,
that if item (3), (4) or (5) is checked, the Issuer or the Trustee may require,
prior to registering any such transfer of the Notes, in their sole discretion,
such written legal opinions, certifications (including an investment letter in
the case of box (3) or (4)) and other information as the Trustee or the Issuer
has reasonably requested to confirm that such transfer is being made pursuant
to an exemption from, or in a transaction not subject to, the registration
requirements of the Securities Act.

 

If none of the
foregoing items (1) through (6) are checked, the Trustee or Registrar shall not
be obligated to register this Note in the name of any person other than the
Holder hereof unless and until the conditions to any such transfer of
registration set forth herein and in Section 2.16 of the Indenture shall
have been satisfied.

 

	
  Dated:

  	
   

  	
   

  	
  Signed:

  	
   

  	
   

  
	
   

  	
   

  	
  (Sign
  exactly as name appears on the other

  side of this Note)

  	
   

  
	
   

  	
   

  
	
   

  	
   

  
	
  Signature
  Guarantee:

  	
   

  	
   

  
	
   

  	
   

  
	
   

  	
  Participant in a recognized Signature Guarantee Medallion Program (or
  other signature guarantor program reasonably acceptable to the Trustee)

  
							

 

 

TO BE COMPLETED BY PURCHASER IF (2) ABOVE IS CHECKED

 

The undersigned
represents and warrants that it is purchasing this Note for its own account or
an account with respect to which it exercises sole investment discretion and
that it and any such account is a “qualified institutional buyer” within the
meaning of Rule 144A under the Securities Act and is aware that the sale to it
is being made in reliance on Rule 144A and acknowledges that it has received
such information regarding the Issuer as the undersigned has requested pursuant
to Rule 144A or has determined not to request such information and that it is
aware that the transferor is relying upon the undersigned’s foregoing representations
in order to claim the exemption from registration provided by Rule 144A.

 

	
  Dated:

  	
   

  	
   

  	
   

  	
   

  
	
   

  	
  NOTICE:   To
  be executed by an executive officer

  

 

 

OPTION OF HOLDER TO ELECT PURCHASE

 

If you want to
elect to have this Note purchased by the Issuer pursuant to Section 4.09 or
Section 4.13 of the Indenture, check the appropriate box:

 

Section 4.09
[      ] Section 4.13
[       ]

 

If you want to
elect to have only part of this Note purchased by the Issuer pursuant to
Section 4.09 or Section 4.13 of the Indenture, state the amount (in
denominations of $1,000 and integral multiples thereof): 
$                   

 

	
  Dated:

  	
   

  	
   

  	
  Signed:

  	
   

  	
   

  
	
   

  	
   

  	
   

  	
  (Sign exactly
  as name

  appears on the other

  side of this Note)

  	
   

  
	
   

  	
   

  
	
   

  	
   

  
	
  Signature
  Guarantee:

  	
   

  	
   

  
	
   

  	
   

  
	
   

  	
  Participant in a recognized Signature Guarantee Medallion Program (or
  other signature guarantor program reasonably acceptable to the Trustee)

  
									

 

 

SCHEDULE OF EXCHANGES OF INTERESTS IN THE GLOBAL NOTE

 

The following
exchanges of a part of this Global Note for an interest in another Global Note
or for a Physical Note, or exchanges of a part of another Global Note or
Physical Note for an interest in this Global Note, have been made:

 

	
  Date of Exchange

  	
   

  	
  Amount of
  decrease

  in

  Principal Amount of

  this Global Note

  	
   

  	
  Amount of
  increase

  in

  Principal Amount of

  this Global Note

  	
   

  	
  Principal
  Amount of

  this Global Note

  following such

  decrease

  (or increase)

  	
   

  	
  Signature
  of

  authorized officer

  of

  Trustee or Note

  CustodianExhibit 4.5

 

NOTE GUARANTEE

 

For value
received, each of the undersigned (including any successor Person under the
Indenture) hereby unconditionally guarantees, jointly and severally, to the
extent set forth in the Indenture (as defined below) to the Holder of this Note
the payment of principal, premium, if any, and interest on this Note in the
amounts and at the times when due and interest on the overdue principal,
premium, if any, of this Note when due, if lawful, and, to the extent permitted
by law, the payment or performance of all other obligations of the Issuer under
the Indenture or the Notes, to the Holder of this Note and the Trustee, all in
accordance with and subject to the terms and limitations of this Note, the Indenture,
including Article Ten thereof, and this Note Guarantee.  This Note Guarantee will become effective in
accordance with Article Ten of the Indenture and its terms shall be evidenced
therein.  The validity and enforceability
of any Note Guarantee shall not be affected by the fact that it is not affixed
to any particular Note.

 

Capitalized
terms used but not defined herein shall have the meanings ascribed to them in
the Indenture, dated as of April 23, 2004, among Curative Health Services,
Inc., a Minnesota corporation (the “Issuer”), the Guarantors named therein and
Wells Fargo Bank, N.A., as trustee (the “Trustee”), as amended or supplemented (the
“Indenture”).

 

The
obligations of the undersigned to the Holders of Notes and to the Trustee pursuant
to this Note Guarantee and the Indenture are expressly set forth in Article Ten
of the Indenture and reference is hereby made to the Indenture for the precise
terms of the Note Guarantee and all of the other provisions of the Indenture to
which this Note Guarantee relates.

 

No director,
officer, employee, incorporator, stockholder, member or manager of any
Guarantor, as such, shall have any liability for any obligations of such
Guarantors under such Guarantors’ Note Guarantee or the Indenture or for any
claim based on, in respect of, or by reason of, such obligation or its
creation.

 

This Note Guarantee shall be governed by, and
construed in accordance with, the laws of the State of New York.

 

This Note
Guarantee is subject to release upon the terms set forth in the Indenture.

 

 

IN WITNESS
WHEREOF, each Guarantor has caused its Note Guarantee to be duly executed.

 

Date:  [        ]

 

	
   

  	
  [Guarantor]

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
  By:

  	
   

  	
   

  
	
   

  	
   

  	
  Name:

  
	
   

  	
   

  	
  Title:

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00065-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00065-of-00352.parquet"}]]