Document:

Guardent, Inc. 2000 Stock Option and Incentive Plan

 Exhibit 4.05 
  
 GUARDENT, INC. 
  
 2000 STOCK OPTION AND INCENTIVE PLAN 
  
 The purpose of this 2000 Stock Option and Incentive Plan (the “Plan”) of Guardent, Inc. (the “Company”) is to provide stock
options and other equity interests in the Company (each an “Award”) to employees, officers, directors, consultants and advisors of the Company and its Subsidiaries, all of whom are eligible to receive Awards under the Plan. Any
person to whom an Award has been granted under the Plan is called a “Participant”. Additional definitions are contained in Section 8. 
  

	2.	Administration 

  
 a. Administration by Board of Directors. The Plan will be administered by the Board of Directors of the Company (the “Board”). The Board,
in its sole discretion, shall have the authority to grant and amend Awards, to adopt, amend and repeal rules relating to the Plan and to interpret and correct the provisions of the Plan and any Award. All decisions by the Board shall be final and
binding on all interested persons. Neither the Company nor any member of the Board shall be liable for any action or determination relating to the Plan. 
  
 b. Appointment of Committees. To the extent permitted by applicable law, the Board may delegate any or all of its powers under the Plan to one or
more committees or subcommittees of the Board (a “Committee”). All references in the Plan to the “Board” shall mean such Committee or the Board. 
  
 c. Delegation to Executive Officers. To the extent permitted by applicable law, the Board may delegate to one or more
executive officers of the Company the power to grant Awards and exercise such other powers under the Plan as the Board may determine, provided that the Board shall fix the maximum number of Awards to be granted and the maximum number of
shares issuable to any one Participant pursuant to Awards granted by such executive officers. 
  

	3.	Stock Available for Awards 

  
 a. Number of Shares. Subject to adjustment under Section 3(c), the aggregate number of shares of Common Stock of the Company (the “Common
Stock”) that may be issued pursuant to the Plan is 10,000,000 shares. If any Award expires, or is terminated, surrendered or forfeited, in whole or in part, the unissued Common Stock covered by such Award shall again be available for the
grant of Awards under the Plan. If shares of Common Stock issued pursuant to the Plan are repurchased by, or are surrendered or forfeited to, the Company at no more than cost, such shares of Common Stock shall again be available for the grant of
Awards under the Plan; provided, however, that the cumulative number of such shares that may be so reissued under the Plan will not exceed 10,000,000 shares. Shares issued under the Plan may consist in whole or in part of authorized but
unissued shares or treasury shares. 

 b. Per-Participant Limit. Subject to adjustment under Section 3(c), no Participant may be granted
Awards during any one fiscal year to purchase more than 1,500,000 shares of Common Stock. 
  
 c. Adjustment to Common Stock. In the event of any stock split, stock dividend, extraordinary cash dividend, recapitalization, reorganization, merger, consolidation, combination, exchange of shares,
liquidation, spin-off, split-up, or other similar change in capitalization or event, (i) the number and class of securities available for Awards under the Plan and the per participant share limit, (ii) the number and class of securities, vesting
schedule and exercise price per share subject to each outstanding Option, (iii) the repurchase price per security subject to repurchase, and (iv) the terms of each other outstanding stock-based Award shall be adjusted by the Company (or substituted
Awards may be made) to the extent the Board shall determine, in good faith, that such an adjustment (or substitution) is appropriate. If Section 7(e)(i) applies for any event, this Section 3(c) shall not be applicable. 
  

	4.	Stock Options 

  
 a. General. The Board may grant options to purchase Common Stock (each, an “Option”) and deter-mine the number of shares of Common
Stock to be covered by each Option, the exercise price of each Option and the conditions and limitations applicable to the exercise of each Option and the Common Stock issued upon the exercise of each Option, including vesting provisions, repurchase
provisions and restrictions relating to applicable federal or state securities laws, as it considers advisable. 
  
 b. Incentive Stock Options. An Option that the Board intends to be an “incentive stock option” as defined in Section 422 of the Code (an
“Incentive Stock Option”) shall be granted only to employees of the Company and shall be subject to and shall be construed consistently with the requirements of Section 422 of the Code. The Board and the Company shall have no
liability if an Option or any part thereof that is intended to be an Incentive Stock Option does not qualify as such. An Option or any part thereof that does not qualify as an Incentive Stock Option is refer-red to herein as a “Nonstatutory
Stock Option”. 
  
 c. Exercise Price. The Board
shall establish the exercise price (or determine the method by which the exercise price shall be determined) at the time each Option is granted and specify it in the applicable option agreement. 
  
 d. Duration of Options. Each Option shall be exercisable at such times
and subject to such terms and conditions as the Board may specify in the applicable option agreement. 
  
 e. Exercise of Option. Options may be exercised only by delivery to the Company of a written notice of exercise signed by the proper person
together with payment in full as specified in Section 4(f) for the number of shares for which the Option is exercised. 
  
 f. Payment Upon Exercise. Common Stock purchased upon the exercise of an Option shall be paid for by one or any combination of the following forms
of payment: 
  
 (i) by check payable to the order of the Company;

 (ii) except as otherwise explicitly provided in the applicable option agreement, and only if the Common
Stock is then publicly traded, delivery of an irrevocable and unconditional undertaking by a creditworthy broker to deliver promptly to the Company sufficient funds to pay the exercise price, or delivery by the Participant to the Company of a copy
of irrevocable and unconditional instructions to a creditworthy broker to deliver promptly to the Company cash or a check sufficient to pay the exercise price; or 
  
 (iii) to the extent explicitly provided in the applicable option agreement, by (x) delivery of shares of Common Stock owned
by the Participant valued at fair market value (as determined by the Board or as determined pursuant to the applicable option agreement), (y) delivery of a promissory note of the Participant to the Company (and delivery to the Company by the
Participant of a check in an amount equal to the par value of the shares purchased), or (z) payment of such other lawful consideration as the Board may deter-mine. 
  

	5.	Restricted Stock 

  
 a. Grants. The Board may grant Awards entitling recipients to acquire shares of Common Stock, subject to (i) delivery to the Company by the
Participant of a check in an amount at least equal to the par value of the shares purchased, and (ii) the right of the Company to repurchase all or part of such shares at their issue price or other stated or formula price from the Participant in the
event that conditions specified by the Board in the applicable Award are not satisfied prior to the end of the applicable restriction period or periods established by the Board for such Award (each, a “Restricted Stock Award”).

  
 b. Terms and Conditions. The Board shall determine the
terms and conditions of any such Restricted Stock Award. Any stock certificates issued in respect of a Restricted Stock Award shall be registered in the name of the Participant and, unless otherwise deter-mined by the Board, deposited by the
Participant, together with a stock power endorsed in blank, with the Company (or its designee). After the expiration of the applicable restriction periods, the Company (or such designee) shall deliver the certificates no longer subject to such
restrictions to the Participant or, if the Participant has died, to the beneficiary designated by a Participant, in a manner determined by the Board, to receive amounts due or exercise rights of the Participant in the event of the Participant’s
death (the “Designated Beneficiary”). In the absence of an effective designation by a Participant, Designated Beneficiary shall mean the Participant’s estate. 
  

	6.	Other Stock-Based Awards 

  
 The Board shall have the right to grant other Awards based upon the Common Stock having such terms and conditions as the Board may determine, including,
without limitation, the grant of shares based upon certain conditions, the grant of securities convertible into Common Stock and the grant of stock appreciation rights, phantom stock awards or stock units. 
  

	7.	General Provisions Applicable to Awards 

  
 a. Transferability of Awards. Except as the Board may otherwise determine or provide in an Award, Awards shall not be sold, assigned, transferred,
pledged or otherwise encumbered by the person to whom they are granted, either voluntarily or by operation of law, 

 except by will or the laws of descent and distribution, and, during the life of the Participant, shall be exercisable
only by the Participant. References to a Participant, to the extent relevant in the context, shall include references to authorized transferees. 
  
 b. Documentation. Each Award under the Plan shall be evidenced by a written instrument in such form as the Board shall determine or as executed by
an officer of the Company pursuant to authority delegated by the Board. Each Award may contain terms and conditions in addition to those set forth in the Plan provided that such terms and conditions do not contravene the provisions of the
Plan. 
  
 c. Board Discretion. The terms of each type of
Award need not be identical, and the Board need not treat Participants uniformly. 
  
 d. Termination of Status. The Board shall determine the effect on an Award of the disability, death, retirement, authorized leave of absence or other change in the employment or other status of a Participant
and the extent to which, and the period during which, the Participant, or the Participant’s legal representative, conservator, guardian or Designated Beneficiary, may exercise rights under the Award. 
  

	e.	Acquisition of the Company 

  
 (i) Consequences of an Acquisition. Upon the consummation of an Acquisition, the Board or the board of directors of the surviving or acquiring
entity (as used in this Section 7(e)(i), also the “Board”), shall, as to outstanding Awards (on the same basis or on different bases, as the Board shall specify), make appropriate provision for the continuation of such Awards by the
Company or the assumption of such Awards by the surviving or acquiring entity and by substituting on an equitable basis for the shares then subject to such Awards either (a) the consideration payable with respect to the outstanding shares of Common
Stock in connection with the Acquisition, (b) shares of stock of the surviving or acquiring corporation or (c) such other securities as the Board deems appropriate, the fair market value of which (as deter-mined by the Board in its sole discretion)
shall not materially differ from the fair market value of the shares of Common Stock subject to such Awards immediately preceding the Acquisition. In addition to or in lieu of the foregoing, with respect to outstanding Options, the Board may, upon
written notice to the affected optionees, provide that one or more Options then outstanding shall become immediately exercisable in full and that such Options must be exercised within a specified number of days of the date of such notice, at the end
of which period such Options shall terminate; or provide that one or more Options then outstanding shall become immediately exercisable in full and shall be terminated in exchange for a cash payment equal to the excess of the fair market value (as
determined by the Board in its sole discretion) for the shares subject to such Options over the exercise price thereof. 
  
 (ii) Acquisition Defined. An “Acquisition” shall mean: (x) the sale of the Company by merger in which the shareholders of the
Company in their capacity as such no longer own a majority of the outstanding equity securities of the Company (or its successor); or (y) any sale of all or substantially all of the assets or capital stock of the Company (other than in a spin-off or
similar transaction) or (z) any other acquisition of the business of the Company, as determined by the Board. 

 (iii) Assumption of Options Upon Certain Events. In connection with a merger or consolidation of
an entity with the Company or the acquisition by the Company of property or stock of an entity, the Board may grant Awards under the Plan in substitution for stock and stock-based awards issued by such entity or an affiliate thereof. The substitute
Awards shall be granted on such terms and conditions as the Board considers appropriate in the circumstances. 
  
 (iv) Pooling-of Interests-Accounting. If the Company proposes to engage in an Acquisition intended to be accounted for as a pooling-of-interests,
and in the event that the provisions of this Plan or of any Award hereunder, or any actions of the Board taken in connection with such Acquisition, are determined by the Company’s or the acquiring company’s independent public accountants
to cause such Acquisition to fail to be accounted for as a pooling-of-interests, then such provisions or actions shall be amended or rescinded by the Board, without the consent of any Participant, to be consistent with pooling-of-interests
accounting treatment for such Acquisition. 
  
 (v) Parachute
Awards. Notwithstanding the provisions of Section 7(e)(i)(A), if, in connection with an Acquisition described therein, a tax under Section 4999 of the Code would be imposed on the Participant (after taking into account the exceptions set forth
in Sections 28OG(b)(4) and 28OG(b)(5) of the Code), then the number of Awards which shall become exercisable, realizable or vested as provided in such section shall be reduced (or delayed), to the minimum extent necessary, so that no such tax would
be imposed on the Participant (the Awards not becoming so accelerated, realizable or vested, the “Parachute Awards”); provided, however, that if the “aggregate present value” of the Parachute Awards would
exceed the tax that, but for this sentence, would be imposed on the Participant under Section 4999 of the Code in connection with the Acquisition, then the Awards shall become immediately exercisable, realizable and vested without regard to the
provisions of this sentence. For purposes of the preceding sentence, the “aggregate present value” of an Award shall be calculated on an after-tax basis (other than taxes imposed by Section 4999 of the Code) and shall be based on
economic principles rather than the principles set forth under Section 28OG of the Code and the regulations promulgated thereunder. All determinations required to be made under this Section 7(e)(iv) shall be made by the Company. 
  
 f. Withholding. Each Participant shall pay to the Company, or make
provisions satisfactory to the Company for payment of, any taxes required by law to be withheld in connection with Awards to such Participant no later than the date of the event creating the tax liability. The Board may allow Participants to satisfy
such tax obligations in whole or in part by transferring shares of Common Stock, including shares retained from the Award creating the tax obligation, valued at their fair market value (as determined by the Board or as determined pursuant to the
applicable option agreement). The Company may, to the extent permitted by law, deduct any such tax obligations from any payment of any kind otherwise due to a Participant. 
  
 g. Amendment of Awards. The Board may amend, modify or terminate any outstanding Award including, but not limited to,
substituting therefor another Award of the same or a different type, changing the date of exercise or realization, and converting an Incentive Stock Option to a Nonstatutory Stock Option, provided that, except as otherwise provided in Section
7(e)(iv), the Participant’s consent to such action shall be required unless the Board determines that the action, taking into account any related action, would not materially and adversely affect the Participant. 

 h. Conditions on Delivery of Stock. The Company will not be obligated to deliver any shares of
Common Stock pursuant to the Plan or to remove restrictions from shares previously delivered under the Plan until (i) all conditions of the Award have been met or removed to the satisfaction of the Company, (ii) in the opinion of the Company’s
counsel, all other legal matters in connection with the issuance and delivery of such shares have been satisfied, including any applicable securities laws and any applicable stock exchange or stock market rules and regulations, and (iii) the
Participant has executed and delivered to the Company such representations or agreements as the Company may consider appropriate to satisfy the requirements of any applicable laws, rules or regulations. 
  
 i. Acceleration. The Board may at any time provide that any Options
shall become immediately exercisable in full or in part, that any Restricted Stock Awards shall be free of some or all restrictions, or that any other stock-based Awards may become exercisable in full or in part or free of some or all restrictions
or conditions, or otherwise realizable in full or in part, as the case may be, despite the fact that the foregoing actions may (i) cause the application of Sections 28OG and 4999 of the Code if a change in control of the Company occurs, or (ii)
disqualify all or part of the Option as an Incentive Stock Option. 
  

	8.	Miscellaneous 

  
 a. Definitions. 
  
 (i) “Company,” for purposes of eligibility under the Plan, shall include any present or future subsidiary corporations of Guardent, Inc.,
as defined in Section 424(f) of the Code (a “Subsidialy”), and any present or future parent corporation of Guardent, Inc., as defined in Section 424(e) of the Code. For purposes of Awards other than Incentive Stock Options, the term
“Company” shall include any other business venture in which the Company has a direct or indirect significant interest, as determined by the Board in its sole discretion. 
  
 (ii) “Code” means the Internal Revenue Code of 1986, as amended, and any regulations promulgated
thereunder. 
  
 (iii) “employee” for purposes of
eligibility under the Plan (but not for purposes of Section 4(b)) shall include a person to whom an offer of employment has been extended by the Company. 
  
 b. No Right To Employment or Other Status. No person shall have any claim or right to be granted an Award, and the grant of an Award shall not be
construed as giving a Participant the right to continued employment or any other relationship with the Company. The Company expressly reserves the right at any time to dismiss or otherwise terminate its relationship with a Participant free from any
liability or claim under the Plan. 
  
 c. No Rights As
Stockholder. Subject to the provisions of the applicable Award, no Participant or Designated Beneficiary shall have any rights as a stockholder with respect to any shares of Common Stock to be distributed with respect to an Award until becoming
the record holder thereof. 

 d. Effective Date and Term of Plan. The Plan shall become effective on the date on which it is
adopted by the Board. No Awards shall be granted under the Plan after the completion of ten years from the date on which the Plan was adopted by the Board, but Awards previously granted may extend beyond that date. 
  
 e. Amendment of Plan. The Board may amend, suspend or terminate the
Plan or any portion thereof at any time. 
  
 f. Governing
Law. The provisions of the Plan and all Awards made hereunder shall be governed by and interpreted in accordance with the laws of Delaware, without regard to any applicable conflicts of law. 
  

	
	 Adopted by the Board of Directors on

	 March 21, 2000

	 Approved by the stockholders on

	 March 21, 2000EMPLMT AGRMENT, DATED AS OF 02/14/03 BY AND BTWN MH MEYERSON & CO AND TIMOTHY DE

 EXHIBIT 10.10 
  
 February 14, 2003 
  
 Mr. Timonthy Demarest 
 24 High Street 
 Summit, New Jersey 07901 
  
 Re: Offer of Employment 
  
 Dear Mr. Demarest: 
  
 I am pleased to extend an offer of employment with M.H. MEYERSON & CO., INC. (“Meyerson” or the “Company”) as Executive Vice
President, Chief Technology Officer reporting directly to the Chief Executive Officer, John P. Leighton (the “CEO”). Your employment with the Company is expected to commence on or about February 18, 2003 (the “Commencement
Date”). 
  
 The terms of the Company’s offer are as
follows: 
  

	 	1.	For the 24 months beginning with your start date and ending the day before your 24 month anniversary (the “Term”), in return for your best efforts, you will receive a base
salary of $700,000 during the Term paid at the annual rate of $350,000. In addition, after the end of the first quarter of this calendar year, you will receive a special bonus of $100,000 to be paid in due course after March 31, 2003.

  

	 	2.	You also will receive a grant of options to purchase 200,000 shares of Meyerson common stock with a strike price of $.48/share that will vest over two years and expire after five
years. You will receive options to purchase an additional 75,000 shares of Meyerson common stock in six months with a strike price based on the then existing market price as determined in accordance with the Company’s 2000 Stock Option Plan or
a newly-created stock option plan. 

  

	 	3.	You will be reviewed six months after the commencement date of your employment for an adjustment to compensation. Any such adjustment will be based solely on your performance.

  

	 	4.	During the Term the Company shall pay you a semi-annual cash incentive bonus (the “Incentive Bonus”) of one and one-half (1.5%) percent of the Company’s “Income
before income taxes” as reflected in the Company’s periodic filings with the Securities and Exchange Commission (the “SEC”). The Incentive Bonus is payable as follows: (i) the Incentive Bonus for the six-month period ending July
31st shall be paid thirty (30) days after the Company files its Report on Form 10-Q for the quarter ended July
31st of the applicable year with the SEC; and (ii) the Incentive Bonus for the period ending January 31st shall be paid thirty (30) days after the Company’s independent auditors (the “Auditors”) shall have completed
their audit of the applicable fiscal year’s results. All calculations of the Incentive Bonuses shall be adjusted upwards or downwards, as the case may be, and any required additional payments by the Company or repayments by you of excess
payments shall be made after the Auditors shall have completed their audit of the applicable fiscal year’s results. You acknowledges that payment of the Incentive Bonus could have an adverse impact on the Company’s ability to maintain
compliance with the net capital rules promulgated under the Securities Exchange Act of 1934, as amended (the “Net Capital Rules”). Accordingly, the Company and you agree that if payment or accrual for payment of the amount due pursuant to
an Incentive Bonus would cause the Company to have less than One Million Five Hundred Thousand Dollars ($1,500,000) in Net Capital (as defined under the Net Capital Rules), the Company shall only be required to pay you, or accrue for payment, such
amount of the Incentive Bonus as would allow the Company to maintain Net Capital of not less than One Million Five Hundred Thousand Dollars ($1,500,000) and the balance of such Incentive Bonus shall be forfeited by you. 

  

	 	5.	Upon construction of a management bonus pool you will be considered for participation at a level to be determined then. Management will use its best efforts to establish that pool
promptly. 

  

	 	6.	You will be eligible for such override of the net profits of Meyerson’s technology business that you will foster, manage and promote as may be mutually agreed upon by you and
the Company. 

  

	 	7.	For the current calendar year, if the amounts to be paid you in paragraphs 4, 5 and 6 do not together equal $225,000, the Company will make up the difference.

	 	8.	If before the end of the Term, you leave Meyerson voluntarily or Meyerson terminates you with cause, other than salary earned as of the date of termination, you shall not receive
any severance, separation payment or other compensation, including any portion of the aforementioned guarantees that has not already been paid to you. If Meyerson terminates your employment without cause before the end of the Term, you will be paid
any portions of the guaranteed amounts that have not already been paid to you provided that you provide Meyerson with a release in a form acceptable to Meyerson. If Meyerson terminates your employment without cause before the end of the Term,
Meyerson will pay you any salary earned but not paid as of the date of termination, whether or not you provide a release. 

  

	 	•	For purposes of this letter, “best efforts” shall include your adherence to reasonable performance standards that the CEO may establish from time to time. For purposes of
this letter, “cause” shall mean: (i) deliberate or intentional failure by you to perform your material duties hereunder, including your intentional refusal to act upon a reasonable instruction from the CEO; (ii) an intentional act of
fraud, embezzlement, or theft or other material violation of law; (iii) intentional wrongful damage to material assets of Meyerson; (iv) intentional wrongful disclosure of material confidential information of Meyerson; (v) intentional wrongful
engagement in any competitive activity which would constitute a breach of this agreement and/or of your duty of loyalty; (vi) intentional breach of any material employment policy of Meyerson; (vii) your failure to maintain any registration, license
or other authorization required to perform your duties hereunder which failure is not cured within 45 days notice to you; or (viii) your violation of any law, rule, or regulation of any governmental authority, securities exchange or association or
other regulatory or self-regulatory body which violation is not cured immediately upon notice to you of such violation. 

  

	 	    	No act, or failure to act, on your part shall be deemed “intentional” if it was due primarily to an error in judgment or negligence, but shall be deemed
“intentional” only if done, or omitted to be done, by you in the absence of good faith and without reasonable belief that your action or omission was in, or not opposed to, the best interest of Meyerson. 

  

	 	7.	You will be eligible to participate in a range of health and welfare benefits, which will be effective the first month following the date of hire. 

  

	 	8.	This offer is contingent upon the following: 

  

	 	•	Your provision of evidence of your ability to work legally in the United States as required by the Immigration Reform and Control Act of 1986; 

  

	 	•	Your successful completion of a drug-screening test (details will follow); 

  

	 	•	Your successful completion of the firms’ screening process, which includes, but is not limited to, receipt of satisfactory reference and background checks, including your
federal income tax return or your W-2 for the past two years; and 

  

	 	•	Your execution of a confidentiality and proprietary information agreement and your obtaining all necessary licenses. 

  

	 	9.	You agree that you are not presently subject to a non-competition agreement, non-solicitation agreement, or any other agreement that may hinder or prevent you from fulfilling, in
whole or in part, your new role at Meyerson. 

  

	 	10.	This letter is not a guarantee of continued employment for any length of time. Thus, you also agree that you will be an employee at will, i.e., you or Meyerson can terminate
your employment at any time, with or without cause. In addition, during your employment, you will be subject to all the management, compliance and other policies of the Company as the Company may determine such policies from time to time.

  

	 	11.	This agreement supersedes all previous discussions and agreements, written or verbal, and constitutes the entire agreement between you and Meyerson. You further agree and
acknowledge that in accepting our offer of employment, you have not relied, to your detriment or otherwise, on any statements, promises, or assurances except those expressly set forth herein. You acknowledge that you have entered this agreement of
your own free will, after the opportunity to obtain advice of counsel, and after ample consideration. This agreement must be signed by both parties and may not be amended except in a writing signed by both parties. This agreement is binding on
Meyerson’s successors and assigns. 

  

	 	12.	You understand that the terms and conditions of this offer are provisional and are subject to Board approval. Management will use its best efforts to obtain that approval
immediately upon your acceptance of this offer. 

  
 We believe that
you will make an important contribution to fulfilling Meyerson’s goals and we look forward to having you join the Meyerson team. 
  
 Sincerely yours, 
  

							
	 /s/ John P. Leighton

	 	 	 	  	 	  
	 John P. Leighton
 Chief Executive Officer
 M.H. MEYERSON & CO., INC.
	 	 	 	 	 	 

 Acknowledged and Accepted 
  

							
				
	 /s/ Timothy Demarest

	 	 	 	 February 14, 2003

	 	  
	 Timothy Demarest
	 	 	 	 Date of Acceptance
	 	 

  

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