Document:

Accredo Health, Incorporated 2002 Long Term Incentive Plan

  Exhibit 4.12 

   

  ACCREDO HEALTH, INCORPORATED 

  2002 LONG-TERM INCENTIVE PLAN 

   

  As amended and restated effective August 18, 2005 

  to reflect the merger (the “Merger”) of Accredo Health, Incorporated with and into a 

  subsidiary of Medco Health Solutions, Inc. (“Medco”) 

   

  ARTICLE I 

  PURPOSE 

   

  1.1. GENERAL. The purpose of the Accredo Health, Incorporated 2002 Long-Term Incentive Plan (the “Plan”) is to promote the success, and enhance the value,
      of Accredo Health, Incorporated (the “Corporation”), and its parent company Medco Health Solutions, Inc. (“Medco”) by linking the personal interests of its employees to those of Medco’s stockholders and by providing such persons with an incentive for
      outstanding performance. The Plan is further intended to provide flexibility to the Corporation in its ability to motivate, attract, and retain the services of employees upon whose judgment, interest, and special effort the successful conduct of the
      Corporation’s operation is largely dependent. Accordingly, the Plan permits the grant of incentive awards from time to time to selected employees. 

   

  ARTICLE 2 

  EFFECTIVE DATE 

   

  2.1. EFFECTIVE DATE. The Plan became effective as of the date it was first approved by both the Corporation’s board and its stockholders. The Plan was
      subsequently amended and as amended approved by the Corporation’s stockholders on November 22, 2004. In connection with the merger of the Corporation with and into a subsidiary of Medco, the plan was assumed by Medco and shares of Medco Common Stock
      were substituted for shares of the Corporation, effective as of August 18, 2005. 

   

  ARTICLE 3 

  DEFINITIONS 

   

  3.1. DEFINITIONS. When a word or phrase appears in this Plan with the initial letter capitalized, and the word or phrase does not commence a sentence, the
      word or phrase shall generally be given the meaning ascribed to it in this Section or in Section 1.1 unless a clearly different meaning is required by the context. The following words and phrases shall have the following meanings: 

   

  (a) “Award” means any Option, Restricted Stock Award, or any other right or interest relating to Stock or cash, granted to a Participant
      under the Plan. 

   

  (b) “Award Agreement” means any written agreement, contract, or other instrument or document evidencing an Award. 

   

  

  (c) “Board” means the Board of Directors of Medco Health Solutions, Inc. 

   

  (d) “Cause” as a reason for a Participant’s termination of employment shall have the meaning assigned such term in the employment agreement,
      if any, between such Participant and the Corporation or an affiliated company, provided, however that if there is no such employment agreement in which such term is defined, “Cause” shall mean any of the following acts by the Participant, as
      determined by the Board: gross neglect of duty, prolonged absence from duty without the consent of the Corporation, intentionally engaging in any activity that is in conflict with or adverse to the business or other interests of the Corporation, or
      willful misconduct, misfeasance or malfeasance of duty which is reasonably determined to be detrimental to the Corporation. 

   

  (e) “Change in Control” means and includes: 

   

  (1) The acquisition by any individual, entity or group (within the meaning of Section 13(d)(3) or 14(d)(2) of the 1934 Act) (a “Person”) of
      beneficial ownership (within the meaning of Rule 13d-3 promulgated under the 1934 Act) of 25% or more of the combined voting power of the then outstanding voting securities of Medco entitled to vote generally in the election of directors (the
      “Outstanding Corporation Voting Securities”); provided, however, that for purposes of this subsection (1), the following acquisitions shall not constitute a Change of Control: (i) any acquisition by a Person who is on the Effective Date the
      beneficial owner of 25% or more of the Outstanding Corporation Voting Securities, (ii) any acquisition directly from Medco, (iii) any acquisition by the Medco, (iv) any acquisition by any employee benefit plan (or related trust) sponsored or
      maintained by Medco or any corporation controlled by Medco, or (v) any acquisition by any corporation pursuant to a transaction which complies with clauses (i), (ii) and (iii) of subsection (3) of this definition; or 

   

  (2) Individuals who, as of the Effective Time, constitute the Board (the “Incumbent Board”) cease for any reason to constitute at least a
      majority of the Board; provided, however, that any individual becoming a director subsequent to the Effective Time whose election, or nomination for election by Medco’s stockholders, was approved by a vote of at least a majority of the directors then
      comprising the Incumbent Board shall be considered as though such individual were a member of the Incumbent Board, but excluding, for this purpose, any such individual whose initial assumption of office occurs as a result of an actual or threatened
      election contest with respect to the election or removal of directors or other actual or threatened solicitation of proxies or consents by or on behalf of a Person other than the Board; or 

   

  (3) Consummation of a reorganization, merger or consolidation or sale or other disposition of all or substantially all of the assets of
      Medco (a “Business Combination”), in each case, unless, following such Business Combination, (i) all or substantially all of the individuals and entities who were  

   

  - 2 - 

   

  

   the beneficial owners of the Outstanding Corporation Voting Securities immediately prior to such Business Combination beneficially own, directly or
      indirectly, more than 50% of the combined voting power of the then outstanding voting securities entitled to vote generally in the election of directors of the corporation resulting from such Business Combination (including, without limitation, a
      corporation which as a result of such transaction owns Medco or all or substantially all of Medco’s assets either directly or through one or more subsidiaries) in substantially the same proportions as their ownership, immediately prior to such
      Business Combination of the Outstanding Corporation Voting Securities, and (ii) no Person (excluding any corporation resulting from such Business Combination or any employee benefit plan (or related trust) of Medco or such corporation resulting from
      such Business Combination) beneficially owns, directly or indirectly, 25% or more of the combined voting power of the then outstanding voting securities of such corporation except to the extent that such ownership existed prior to the Business
      Combination, and (iii) at least a majority of the members of the board of directors of the corporation resulting from such Business Combination were members of the Incumbent Board at the time of the execution of the initial agreement, or of the
      action of the Board, providing for such Business Combination; or 

   

  (4) Approval by the stockholders of Medco of a complete liquidation or dissolution of Medco. 

   

  (f) “Code” means the Internal Revenue Code of 1986, as amended from time to time. 

   

  (g) “Committee” means the committee of the Board described in Article 4. 

   

  (h) “Corporation” means Accredo Health, Incorporated, a Delaware corporation. 

   

  (i) “Covered Employee” means a covered employee as defined in Code Section 162(m)(3). 

   

  (j) “Disability” shall mean any illness or other physical or mental condition of a Participant that renders the Participant incapable of
      performing his customary and usual duties for the Corporation, or any medically determinable illness or other physical or mental condition resulting from a bodily injury, disease or mental disorder which, in the judgment of the Committee, is
      permanent and continuous in nature. The Committee may require such medical or other evidence as it deems necessary to judge the nature and permanency of the Participant’s condition. Notwithstanding the above, with respect to an Incentive Stock
      Option, Disability shall mean Permanent and Total Disability as defined in Section 22(e)(3) of the Code. 

   

  - 3 - 

   

  

  (k) “Effective Date” has the meaning assigned such term in Section 2.1. 

   

  (l) “Fair Market Value”, with respect to grants made after the effective time of the Merger, shall mean the average (mean) of the highest
      and lowest sales prices of a share of Common Stock, as reported on the New York Stock Exchange (or any other reporting system selected by the Committee, in its sole discretion) on the date as of which the determination is being made or, if no sale of
      shares of Common Stock is reported on this date, on the next preceding day on which there were sales of shares of Common Stock reported. Prior to the effective time of the Merger, Fair Market Value means on any date, (i) if the Stock is listed on a
      securities exchange or is traded over the Nasdaq National Market, the closing sales price on such exchange or over such system on such date or, in the absence of reported sales on such date, the closing sales price on the immediately preceding date
      on which sales were reported, or (ii) if the Stock is not listed on a securities exchange or traded over the Nasdaq National Market, the mean between the bid and offered prices as quoted by Nasdaq for such date, provided that if the Stock is not
      quoted on Nasdaq or it is determined that the fair market value is not properly reflected by such Nasdaq quotations, Fair Market Value will be determined by such other method as the Committee determines in good faith to be reasonable. 

   

  (m) “Incentive Stock Option” means an Option that is intended to meet the requirements of Section 422 of the Code or any successor provision
      thereto. 

   

  (n) “Medco” means Medco Health Solutions, Inc. 

   

  (o) “Non-Qualified Stock Option” means an Option that is not an Incentive Stock Option. 

   

  (p) “Option” means a right granted to a Participant under Article 7 of the Plan to purchase Stock at a specified price during specified time
      periods. An Option may be either an Incentive Stock Option or a Non-Qualified Stock Option. 

   

  (q) “Other Stock-Based Award” means a right, granted to a Participant that relates to or is valued by reference to Stock or other Awards
      relating to Stock. 

   

  (r) “Parent” means a corporation which owns or beneficially owns a majority of the outstanding voting stock or voting power of the
      Corporation. Notwithstanding the above, with respect to an Incentive Stock Option, Parent shall have the meaning set forth in Section 424(e) of the Code. 

   

  (s) “Participant” means a person who, as an employee, officer, consultant or director of the Corporation or any Subsidiary, has been granted
      an Award under the Plan. 

   

  (t) “Plan” means the Accredo Health, Incorporated 2002 Long-Term Incentive Plan, as amended from time to time. 

   

  - 4 - 

   

  

  (u) “Restricted Stock Award” means Stock granted to a Participant under Article 8 that is subject to certain restrictions and to risk of
      forfeiture. 

   

  (v) “Retirement” means a Participant’s voluntary termination of employment with the Corporation, Parent or Subsidiary after attaining age
      55. 

   

  (w) “Stock” means the $.01 par value common stock of Medco and such other securities of Medco as may be substituted for Stock pursuant to
      Article 10. 

   

  (x) “Subsidiary” means any corporation, limited liability company, partnership or other entity of which a majority of the outstanding voting
      stock or voting power is beneficially owned directly or indirectly by the Corporation. Notwithstanding the above, with respect to an Incentive Stock Option, Subsidiary shall have the meaning set forth in Section 424(f) of the Code. 

   

  (y) “1933 Act” means the Securities Act of 1933, as amended from time to time. 

   

  (z) “1934 Act” means the Securities Exchange Act of 1934, as amended from time to time. 

   

  ARTICLE 4 

  ADMINISTRATION 

   

  4.1. COMMITTEE. The Plan shall be administered by a committee appointed by the Board (which Committee shall consist of two or more directors) or, at the
      discretion of the Board from time to time, the Plan may be administered by the Board. The Committee shall consist of two or more members of the Board. It is intended that the directors appointed to serve on the Committee shall be “non-employee
      directors” (within the meaning of Rule 16b-3 promulgated under the 1934 Act) and “outside directors” (within the meaning of Code Section 162(m) and the regulations thereunder) to the extent that Rule 16b-3 and, if necessary for relief from the
      limitation under Code Section 162(m) and such relief is sought by Medco, Code Section 162(m), respectively, are applicable. However, the mere fact that a Committee member shall fail to qualify under either of the foregoing requirements shall not
      invalidate any Award made by the Committee which Award is otherwise validly made under the Plan. The members of the Committee shall be appointed by, and may be changed at any time and from time to time in the discretion of, the Board. During any time
      that the Board is acting as administrator of the Plan, it shall have all the powers of the Committee hereunder, and any reference herein to the Committee (other than in this Section 4.1) shall include the Board. 

   

  4.2. ACTION BY THE COMMITTEE. For purposes of administering the Plan, the following rules of procedure shall govern the Committee. A majority of the
      Committee shall constitute a quorum. The acts of a majority of the members present at any meeting at which a quorum is present, and acts approved unanimously in writing by  

   

  - 5 - 

   

  

   the members of the Committee in lieu of a meeting, shall be deemed the acts of the Committee. Each member of the Committee is entitled to, in good faith, rely or act upon
      any report or other information furnished to that member by any officer or other employee of the Corporation or any Parent or Subsidiary, the Corporation’s independent certified public accountants, or any executive compensation consultant or other
      professional retained by the Corporation to assist in the administration of the Plan. 

   

  4.3. AUTHORITY OF COMMITTEE. Except as provided below, the Committee has the exclusive power, authority and discretion to: 

   

  (a) Designate Participants; 

   

  (b) Determine the type or types of Awards to be granted to each Participant; 

   

  (c) Determine the number of Awards to be granted and the number of shares of Stock to which an Award will relate; 

   

  (d) Determine the terms and conditions of any Award granted under the Plan, including but not limited to, the exercise price, grant price,
      or purchase price, any restrictions or limitations on the Award, any schedule for lapse of forfeiture restrictions or restrictions on the exercisability of an Award, and accelerations or waivers thereof, based in each case on such considerations as
      the Committee in its sole discretion determines; 

   

  (e) Accelerate the vesting or lapse of restrictions of any outstanding Award, based in each case on such considerations as the Committee in
      its sole discretion determines; 

   

  (f) Determine whether, to what extent, and under what circumstances an Award may be settled in, or the exercise price of an Award may be
      paid in, cash, Stock, other Awards, or other property, or an Award may be canceled, forfeited, or surrendered; 

   

  (g) Prescribe the form of each Award Agreement, which need not be identical for each Participant; 

   

  (h) Decide all other matters that must be determined in connection with an Award; 

   

  (i) Establish, adopt or revise any rules and regulations as it may deem necessary or advisable to administer the Plan; 

   

  (j) Make all other decisions and determinations that may be required under the Plan or as the Committee deems necessary or advisable to
      administer the Plan; 

   

  - 6 - 

   

  

  (k) Amend the Plan or any Award Agreement as provided herein; and 

   

  (l) Adopt such modifications, procedures, and subplans as may be necessary or desirable to comply with provisions of the laws of non-U.S.
      jurisdictions in which the Corporation or any Parent or Subsidiary may operate, in order to assure the viability of the benefits of Awards granted to participants located in such other jurisdictions and to meet the objectives of the Plan. 

   

  Notwithstanding the above, the Board or the Committee may and hereby does expressly delegate to the Chief Executive Officer of Medco all of the Committee’s
      authority under subsections (a), (b) and (c) above; provided that such delegation shall be limited to a number of Awards specified by the Committee; and provided further that no officer may grant Awards to himself or to eligible Participants who, at
      the time of grant, are or are anticipated to become, either (i) Covered Employees or (ii) persons subject to the insider trading restrictions of Section 16 of the 1934 Act. 

   

  4.4. DECISIONS BINDING. The Committee’s interpretation of the Plan, any Awards granted under the Plan, any Award Agreement and all decisions and
      determinations by the Committee with respect to the Plan are final, binding, and conclusive on all parties. 

   

  ARTICLE 5 

  SHARES SUBJECT TO THE PLAN 

  (Post-Merger) 

   

  5.1. NUMBER OF SHARES. Subject to adjustment as provided in Section 10.1, the aggregate number of shares of Stock reserved and available for Awards shall be
      5,711,695, of which not more than 10% may be granted as Awards of Restricted Stock. As of the Effective Time, Awards under the Plan were outstanding with respect to 3,775,093 shares. 

   

  5.2. LAPSED AWARDS. To the extent that an Award is canceled, terminates, expires or lapses for any reason, any shares of Stock subject to the Award will
      again be available for the grant of an Award under the Plan. 

   

  5.3. STOCK DISTRIBUTED. Any Stock distributed pursuant to an Award may consist, in whole or in part, of authorized and unissued Stock, treasury Stock or
      Stock purchased on the open market. 

   

  5.4. LIMITATION ON AWARDS. Notwithstanding any provision in the Plan to the contrary (but subject to adjustment as provided in Section 10.1), the maximum
      number of shares of Stock with respect to one or more Options that may be granted during any one calendar year under the Plan to any one Participant shall be 467,135. The maximum fair market value (measured as of the date of grant) of any Restricted
      Stock Awards that may be received by any one Participant (less any consideration paid by the Participant for such Award) during any one calendar year under the Plan shall be $2,000,000. 

   

  - 7 - 

   

  

  ARTICLE 6 

  ELIGIBILITY 

   

  6.1. GENERAL. Awards may be granted only to individuals who are employees of the Corporation or a Subsidiary. 

   

  ARTICLE 7 

  STOCK OPTIONS 

   

  7.1. GENERAL. The Committee is authorized to grant Options to Participants on the following terms and conditions: 

   

  (a) EXERCISE PRICE. The exercise price per share of Stock under an Option shall be determined by the Committee, provided that the exercise
      price for any Option shall not be less than the Fair Market Value as of the date of the grant. 

   

  (b) TIME AND CONDITIONS OF EXERCISE. The Committee shall determine the time or times at which an Option may be exercised in whole or in
      part, subject to Section 7.1(e). The Committee also shall determine the performance or other conditions, if any, that must be satisfied before all or part of an Option may be exercised or vested. The Committee may waive any exercise or vesting
      provisions at any time in whole or in part based upon factors as the Committee may determine in its sole discretion so that the Option becomes exercisable or vested at an earlier date. The Committee may permit an arrangement whereby receipt of Stock
      upon exercise of an Option is delayed until a specified future date. 

   

  (c) PAYMENT. The Committee shall determine the methods by which the exercise price of an Option may be paid, the form of payment, including,
      without limitation, cash, shares of Stock, or other property (including “cashless exercise” arrangements), and the methods by which shares of Stock shall be delivered or deemed to be delivered to Participants; provided, however, that if shares of
      Stock are used to pay the exercise price of an Option, such shares must have been held by the Participant for at least six months. 

   

  (d) EVIDENCE OF GRANT. All Options shall be evidenced by a term sheet summarizing the terms and conditions of the Award. The summary shall
      include such provisions, not inconsistent with the Plan, as may be specified by the Committee. 

   

  (e) EXERCISE TERM. In no event may any Option be exercisable for more than ten years from the date of its grant. 

   

  - 8 - 

   

  

  7.2. INCENTIVE STOCK OPTIONS. The terms of any Incentive Stock Options granted under the Plan must comply with the following additional rules: 

   

  (a) EXERCISE PRICE. The exercise price per share of Stock shall be set by the Committee, provided that the exercise price for any Incentive
      Stock Option shall not be less than the Fair Market Value as of the date of the grant. 

   

  (b) EXERCISE. In no event may any Incentive Stock Option be exercisable for more than ten years from the date of its grant. 

   

  (c) LAPSE OF OPTION. An Incentive Stock Option shall lapse under the earliest of the following circumstances; provided, however, that the
      Committee may, prior to the lapse of the Incentive Stock Option under the circumstances described in paragraphs (3), (4) and (5) below, provide in writing that the Option will extend until a later date, but if the Option is exercised after the dates
      specified in paragraphs (3), (4) and (5) below, it will automatically become a Non-Qualified Stock Option: 

   

  (1) The Incentive Stock Option shall lapse as of the option expiration date set forth in the Award summary. 

   

  (2) The Incentive Stock Option shall lapse ten years after it is granted, unless an earlier time is set in the Award Agreement. 

   

  (3) If the Participant terminates employment for any reason other than as provided in paragraph (4) or (5) below, the Incentive Stock Option
      shall lapse, unless it is previously exercised, three months after the Participant’s termination of employment; provided, however, that if the Participant’s employment is terminated by the Corporation for Cause or by the Participant without the
      consent of the Corporation, the Incentive Stock Option shall (to the extent not previously exercised) lapse immediately. 

   

  (4) If the Participant terminates employment by reason of his Disability, the Incentive Stock Option shall lapse, unless it is previously
      exercised, one year after the Participant’s termination of employment. 

   

  (5) If the Participant dies while employed, or during the three-month period described in paragraph (3) or during the one-year period
      described in paragraph (4) and before the Option otherwise lapses, the Option shall lapse one year after the Participant’s death. Upon the Participant’s death, any exercisable Incentive Stock Options may be exercised by the Participant’s beneficiary,
      determined in accordance with Section 9.5. 

   

  Unless the exercisability of the Incentive Stock Option is accelerated as provided in Article 9, if a Participant exercises an Option after termination of
      employment, the Option may be exercised only with respect to the shares that were otherwise vested on the Participant’s termination of employment. 

   

  - 9 - 

   

  

  (d) INDIVIDUAL DOLLAR LIMITATION. The aggregate Fair Market Value (determined as of the time an Award is made) of all shares of Stock with
      respect to which Incentive Stock Options are first exercisable by a Participant in any calendar year may not exceed $100,000.00. 

   

  (e) TEN PERCENT OWNERS. No Incentive Stock Option shall be granted to any individual who, at the date of grant, owns stock possessing more
      than ten percent of the total combined voting power of all classes of stock of the Corporation or any Parent or Subsidiary unless the exercise price per share of such Option is at least 110% of the Fair Market Value per share of Stock at the date of
      grant and the Option expires no later than five years after the date of grant. 

   

  (f) EXPIRATION OF INCENTIVE STOCK OPTIONS. No Award of an Incentive Stock Option may be made pursuant to the Plan after the day immediately
      prior to the tenth anniversary of the Effective Date. 

   

  (g) RIGHT TO EXERCISE. During a Participant’s lifetime, an Incentive Stock Option may be exercised only by the Participant or, in the case
      of the Participant’s Disability, by the Participant’s guardian or legal representative. 

   

  (h) DIRECTORS. The Committee may not grant an Incentive Stock Option to a non-employee director. The Committee may grant an Incentive Stock
      Option to a director who is also an employee of the Corporation or Parent or Subsidiary but only in that individual’s position as an employee and not as a director. 

   

  ARTICLE 8 

  RESTRICTED STOCK AWARDS 

   

  8.1. GRANT OF RESTRICTED STOCK. The Committee is authorized to make Awards of Restricted Stock to Participants in such amounts and subject to such terms and
      conditions as may be selected by the Committee. All Awards of Restricted Stock shall be evidenced by a Restricted Stock Award Agreement. 

   

  8.2. ISSUANCE AND RESTRICTIONS. Restricted Stock shall be subject to such restrictions on transferability and other restrictions as the Committee may impose
      (including, without limitation, limitations on the right to vote Restricted Stock or the right to receive dividends on the Restricted Stock). These restrictions may lapse separately or in combination at such times, under such circumstances, in such
      installments, upon the satisfaction of performance goals or otherwise, as the Committee determines at the time of the grant of the Award or thereafter. 

   

  8.3. FORFEITURE. Except as otherwise determined by the Committee at the time of the grant of the Award or thereafter, upon termination of employment during
      the applicable restriction period or upon failure to satisfy a performance goal during the applicable restriction period, Restricted Stock that is at that time subject to restrictions  

   

  - 10 - 

   

  

   shall be forfeited and reacquired by Medco; provided, however, that the Committee may provide in any Award Agreement or summary that restrictions or forfeiture conditions
      relating to Restricted Stock will be waived in whole or in part in the event of terminations resulting from specified causes, and the Committee may in other cases waive in whole or in part restrictions or forfeiture conditions relating to Restricted
      Stock. 

   

  8.4. CERTIFICATES FOR RESTRICTED STOCK. Restricted Stock granted under the Plan may be evidenced in such manner as the Committee shall determine. If
      certificates representing shares of Restricted Stock are registered in the name of the Participant, certificates must bear an appropriate legend referring to the terms, conditions, and restrictions applicable to such Restricted Stock. 

   

  ARTICLE 9 

  PROVISIONS APPLICABLE TO AWARDS 

   

  9.1. STAND-ALONE, TANDEM, AND SUBSTITUTE AWARDS. Awards granted under the Plan may, in the discretion of the Committee, be granted either alone or in
      addition to, in tandem with, or in substitution for, any other Award granted under the Plan. If an Award is granted in substitution for another Award, the Committee may require the surrender of such other Award in consideration of the grant of the
      new Award. Awards granted in addition to or in tandem with other Awards may be granted either at the same time as or at a different time from the grant of such other Awards. 

   

  9.2. TERM OF AWARD. The term of each Award shall be for the period as determined by the Committee, provided that in no event shall the term of any Incentive
      Stock Option exceed a period of ten years from the date of its grant (or, if Section 7.2(e) applies, five years from the date of its grant). 

   

  9.3. FORM OF PAYMENT FOR AWARDS. Subject to the terms of the Plan and any applicable law or Award Agreement, payments or transfers to be made by the
      Corporation or a Parent or Subsidiary on the grant or exercise of an Award may be made in such form as the Committee determines at or after the time of grant, including without limitation, cash, Stock, other Awards, or other property, or any
      combination, and may be made in a single payment or transfer, in installments, or on a deferred basis, in each case determined in accordance with rules adopted by, and at the discretion of, the Committee. 

   

  9.4. LIMITS ON TRANSFER. No right or interest of a Participant in any unexercised or restricted Award may be pledged, encumbered, or hypothecated to or in
      favor of any party other than the Corporation or a Parent or Subsidiary, or shall be subject to any lien, obligation, or liability of such Participant to any other party other than the Corporation or a Parent or Subsidiary. No unexercised or
      restricted Award shall be assignable or transferable by a Participant other than by will or the laws of descent and distribution or, except in the case of an Incentive Stock Option and only to the extent specifically authorized by the Committee,
      pursuant to a domestic relations order that would satisfy Section 414(p)(1)(A) of the Code if such Section applied to an Award under the Plan; provided, however, that the Committee may (but need not) permit other  

   

  - 11 - 

   

  

   transfers where the Committee concludes that such transferability (i) does not result in accelerated taxation, (ii) does not cause any Option intended to be an Incentive
      Stock Option to fail to be described in Code Section 422(b), and (iii) is otherwise appropriate and desirable, taking into account any factors deemed relevant, including without limitation, any state or federal tax or securities laws or regulations
      applicable to transferable Awards. Nothing in this Section 9.4 shall obligate the Committee to allow transfers pursuant to a domestic relations order. 

   

  9.5. BENEFICIARIES. Notwithstanding Section 9.4, a Participant may, in the manner and to the extent determined by the Committee, designate a beneficiary to
      exercise the rights of the Participant and to receive any distribution with respect to any Award upon the Participant’s death. A beneficiary, legal guardian, legal representative, or other person claiming any rights under the Plan is subject to all
      terms and conditions of the Plan and any Award Agreement applicable to the Participant, except to the extent the Plan and Award Agreement otherwise provide, and to any additional restrictions deemed necessary or appropriate by the Committee. If no
      beneficiary has been designated or survives the Participant, payment shall be made to the Participant’s estate. Subject to the foregoing, a beneficiary designation may be changed or revoked by a Participant at any time provided the change or
      revocation is filed with the Committee. Nothing in this Section 9.5 shall obligate the Committee to allow beneficiary designations. 

   

  9.6. STOCK CERTIFICATES. All Stock issuable under the Plan is subject to any stop-transfer orders and other restrictions as the Committee deems necessary or
      advisable to comply with federal or state securities laws, rules and regulations and the rules of any national securities exchange or automated quotation system on which the Stock is listed, quoted, or traded. The Committee may place legends on any
      Stock certificate to reference restrictions applicable to the Stock. 

   

  9.7. ACCELERATION UPON DEATH, RETIREMENT OR DISABILITY. Except as otherwise provided in an Award Agreement, summary of terms or Rules and Regulations
      adopted by the Committee, upon the Participant’s death, Retirement or Disability during his employment or service as a consultant or director, all outstanding Options shall become fully exercisable and all restrictions on outstanding Restricted Stock
      Awards shall lapse. Any Option shall thereafter continue or lapse in accordance with the other provisions of the Plan and the Award Agreement. To the extent that this provision causes Incentive Stock Options to exceed the dollar limitation set forth
      in Section 7.2(d), the excess Options shall be deemed to be Non-Qualified Stock Options. 

   

  9.8. ACCELERATION UPON A CHANGE IN CONTROL. Except as otherwise provided in an Award Agreement, summary of terms or Rules and Regulations adopted by the
      Committee, upon the occurrence of a Change in Control, all outstanding Options shall become fully exercisable and all restrictions on outstanding Awards shall lapse. To the extent that this provision causes Incentive Stock Options to exceed the
      dollar limitation set forth in Section 7.2(d), the excess Options shall be deemed to be Non-Qualified Stock Options. 

   

  - 12 - 

   

  

  9.9. ACCELERATION FOR ANY OTHER REASON. Regardless of whether an event has occurred as described in Section 9.7 or 9.8 above, the Committee may in its sole
      discretion at any time determine that all or a portion of a Participant’s Options shall become fully or partially exercisable, and/or that all or a part of the restrictions on all or a portion of the outstanding Restricted Stock Awards shall lapse,
      in each case, as of such date as the Committee may, in its sole discretion, declare. The Committee may discriminate among Participants and among Awards granted to a Participant in exercising its discretion pursuant to this Section 9.10. 

   

  9.10. EFFECT OF ACCELERATION. If an Award is accelerated under Section 9.8 or 9.9, the Committee may, in its sole discretion, provide (i) that the Award
      will expire after a designated period of time after such acceleration to the extent not then exercised, (ii) that the Award will be settled in cash rather than Stock, (iii) that, if the Award will be assumed by another party to a transaction giving
      rise to the acceleration or otherwise be equitably converted or substituted in connection with such transaction, (iv) that the Award may be settled by payment in cash or cash equivalents equal to the excess of the Fair Market Value of the underlying
      Stock, as of a specified date associated with the transaction, over the exercise price of the Award, or (v) any combination of the foregoing. The Committee’s determination need not be uniform and may be different for different Participants whether or
      not such Participants are similarly situated. 

   

  9.11. PERFORMANCE GOALS. The Committee may determine that any Award granted pursuant to this Plan to a Participant (including, but not limited to,
      Participants who are Covered Employees) shall be determined solely on the basis of (a) the achievement by the Corporation or a Parent or Subsidiary of a specified target return, or target growth in return, on equity or assets, (b) the achievement by
      the Corporation or a Parent or Subsidiary of a specified target total stockholder return (stock price appreciation plus reinvested dividends), or target growth in total stockholder return, (c) the Corporation’s, Parent’s or Subsidiary’s stock price,
      (d) the achievement by an individual or a business unit of the Corporation, Parent or Subsidiary of a specified target, or target growth in, revenues, net income or earnings per share, or (e) any combination of the goals set forth in (a) through (d)
      above. If an Award is made on such basis, the Committee shall establish goals prior to the beginning of the period for which such performance goal relates (or such later date as may be permitted under Code Section 162(m) or the regulations
      thereunder) and the Committee has the right for any reason to reduce (but not increase) any Award, notwithstanding the achievement of a specified goal. Any payment of an Award granted with performance goals shall be conditioned on the written
      certification of the Committee in each case that the performance goals and any other material conditions were satisfied. 

   

  9.14. TERMINATION OF EMPLOYMENT. Whether military, government or other service or other leave of absence shall constitute a termination of employment shall
      be determined in each case by the Committee at its discretion, and any determination by the Committee shall be final and conclusive. A termination of employment shall not occur (i) in a circumstance in which a Participant transfers from the
      Corporation to one of its Parents or Subsidiaries, transfers from a Parent or Subsidiary to the Corporation, or  

   

  - 13 - 

   

  

   transfers from one Parent or Subsidiary to another Parent or Subsidiary, or (ii) in the discretion of the Committee as specified at or prior to such occurrence, in the
      case of a spin-off, sale, or disposition of the Participant’s employer from the Corporation or any Parent or Subsidiary. To the extent that this provision causes Incentive Stock Options to extend beyond three months from the date a Participant is
      deemed to be an employee of the Corporation, a Parent or Subsidiary for purposes of Section 424(f) of the Code, the Options held by such Participant shall be deemed to be Non-Qualified Stock Options. 

   

  ARTICLE 10 

  CHANGES IN CAPITAL STRUCTURE 

   

  10.1. GENERAL. In the event of a corporate transaction involving the Corporation (including, without limitation, any stock dividend, stock split,
      extraordinary cash dividend, recapitalization, reorganization, merger, consolidation, split-up, spin-off, combination or exchange of shares), the authorization limits under Section 5.1 and 5.4 shall be adjusted proportionately, and the Committee may
      adjust Awards to preserve the benefits or potential benefits of the Awards. Action by the Committee may include: (i) adjustment of the number and kind of shares which may be delivered under the Plan; (ii) adjustment of the number and kind of shares
      subject to outstanding Awards; (iii) adjustment of the exercise price of outstanding Awards; and (iv) any other adjustments that the Committee determines to be equitable. In addition, the Committee may, in its sole discretion, provide (i) that Awards
      will be settled in cash rather than Stock, (ii) that Awards will become immediately vested and exercisable and will expire after a designated period of time to the extent not then exercised, (iii) that Awards will be assumed by another party to a
      transaction or otherwise be equitably converted or substituted in connection with such transaction, (iv) that outstanding Awards may be settled by payment in cash or cash equivalents equal to the excess of the Fair Market Value of the underlying
      Stock, as of a specified date associated with the transaction, over the exercise price of the Award, or (v) any combination of the foregoing. The Committee’s determination need not be uniform and may be different for different Participants whether or
      not such Participants are similarly situated. Without limiting the foregoing, in the event a stock dividend or stock split is declared upon the Stock, the authorization limits under Section 5.1 and 5.4 shall be increased proportionately, and the
      shares of Stock then subject to each Award shall be increased proportionately without any change in the aggregate purchase price therefor. 

   

  ARTICLE 11 

  AMENDMENT, MODIFICATION AND TERMINATION 

   

  11.1. AMENDMENT, MODIFICATION AND TERMINATION. Subject to Section 11.2, the Board or the Committee may, at any time and from time to time, amend, modify or
      terminate the Plan without stockholder approval; provided, however, that the Board or Committee may condition any amendment or modification on the approval of stockholders of the Corporation if such approval is necessary or deemed advisable with
      respect to tax, securities, or other applicable laws, policies, or regulations; and provided further that the last sentence of Section 11.2 may not be amended or modified without stockholder approval. 

   

  - 14 - 

   

  

  11.2. AWARDS PREVIOUSLY GRANTED. No termination, amendment, or modification of the Plan shall adversely affect any Award previously granted under the Plan,
      without the written consent of the Participant. At any time and from time to time, the Committee may amend, modify or terminate any outstanding Award without approval of the Participant; provided, however, that: 

   

  (a) subject to the terms of the applicable Award Agreement, such amendment, modification, or termination shall not, without the
      Participant’s consent, reduce or diminish the value of such Award determined as if the Award had been exercised, vested, cashed in or otherwise settled on the date of such amendment or termination; 

   

  (b) the original term of any Option may not be extended without the prior approval of the stockholders of Medco; and 

   

  (c) except as otherwise provided in Article 10, the exercise price of any Option may not be reduced, directly or indirectly, without the
      prior approval of the stockholders of Medco. 

   

  ARTICLE 12 

  GENERAL PROVISIONS 

   

  12.1. NO RIGHTS TO AWARDS. No Participant or any eligible participant shall have any claim to be granted any Award under the Plan, and neither the
      Corporation, Medco nor the Committee is obligated to treat Participants or eligible participants uniformly. 

   

  12.2. NO STOCKHOLDER RIGHTS. No Award gives the Participant any of the rights of a stockholder of Medco unless and until shares of Stock are in fact issued
      to such person in connection with such Award. 

   

  12.3. WITHHOLDING. The Corporation or any Parent or Subsidiary shall have the authority and the right to deduct or withhold, or require a Participant to
      remit to the Corporation, an amount sufficient to satisfy federal, state, and local taxes (including the Participant’s FICA obligation) required by law to be withheld with respect to any taxable event arising as a result of the Plan. With respect to
      withholding required upon any taxable event under the Plan, the Committee may, at the time the Award is granted or thereafter, require or permit that any such withholding requirement be satisfied, in whole or in part, by withholding from the Award
      shares of Stock having a Fair Market Value on the date of withholding equal to the minimum amount (and not any greater amount) required to be withheld for tax purposes, all in accordance with such procedures as the Committee establishes. 

   

  - 15 - 

   

  

  12.4. NO RIGHT TO CONTINUED SERVICE. Nothing in the Plan or any Award Agreement shall interfere with or limit in any way the right of the Corporation or any
      Parent or Subsidiary to terminate any Participant’s employment or status as an officer, director or consultant at any time, nor confer upon any Participant any right to continue as an employee, officer, director or consultant of the Corporation or
      any Parent or Subsidiary. 

   

  12.5. UNFUNDED STATUS OF AWARDS. The Plan is intended to be an “unfunded” plan for incentive and deferred compensation. With respect to any payments not yet
      made to a Participant pursuant to an Award, nothing contained in the Plan or any Award Agreement shall give the Participant any rights that are greater than those of a general creditor of the Corporation or any Parent or Subsidiary. 

   

  12.6. INDEMNIFICATION. To the extent allowable under applicable law, each member of the Committee shall be indemnified and held harmless by Medco from any
      loss, cost, liability, or expense that may be imposed upon or reasonably incurred by such member in connection with or resulting from any claim, action, suit, or proceeding to which such member may be a party or in which he may be involved by reason
      of any action or failure to act under the Plan and against and from any and all amounts paid by such member in satisfaction of judgment in such action, suit, or proceeding against him provided he gives Medco an opportunity, at its own expense, to
      handle and defend the same before he undertakes to handle and defend it on his own behalf. The foregoing right of indemnification shall not be exclusive of any other rights of indemnification to which such persons may be entitled under Medco’s
      Certificate of Incorporation or Bylaws, as a matter of law, or otherwise, or any power that Medco may have to indemnify them or hold them harmless. 

   

  12.7. RELATIONSHIP TO OTHER BENEFITS. No payment under the Plan shall be taken into account in determining any benefits under any pension, retirement,
      savings, profit sharing, group insurance, welfare or benefit plan of the Corporation or any Parent or Subsidiary unless provided otherwise in such other plan. 

   

  12.8. EXPENSES. The expenses of administering the Plan shall be borne by the Corporation and its Parents or Subsidiaries. 

   

  12.9. TITLES AND HEADINGS. The titles and headings of the Sections in the Plan are for convenience of reference only, and in the event of any conflict, the
      text of the Plan, rather than such titles or headings, shall control. 

   

  12.10. GENDER AND NUMBER. Except where otherwise indicated by the context, any masculine term used herein also shall include the feminine; the plural shall
      include the singular and the singular shall include the plural. 

   

  12.11. FRACTIONAL SHARES. No fractional shares of Stock shall be issued and the Committee shall determine, in its discretion, whether cash shall be given in
      lieu of fractional shares or whether such fractional shares shall be eliminated by rounding up. 

   

  - 16 - 

   

  

  12.12. GOVERNMENT AND OTHER REGULATIONS. The obligation of Medco to make payment of awards in Stock or otherwise shall be subject to all applicable laws,
      rules, and regulations, and to such approvals by government agencies as may be required. Medco shall be under no obligation to register under the 1933 Act, or any state securities act, any of the shares of Stock issued in connection with the Plan.
      The shares issued in connection with the Plan may in certain circumstances be exempt from registration under the 1933 Act, and the Corporation may restrict the transfer of such shares in such manner as it deems advisable to ensure the availability of
      any such exemption. 

   

  12.13. GOVERNING LAW. To the extent not governed by federal law, the Plan and all Award Agreements shall be construed in accordance with and governed by the
      laws of the State of Tennessee. 

   

  12.14. ADDITIONAL PROVISIONS. Each Award Agreement may contain such other terms and conditions as the Committee may determine; provided that such other
      terms and conditions are not inconsistent with the provisions of this Plan. 

   

  - 17 -Exhibit 4.13

    

     

      

     
    EXPRESS SCRIPTS, INC.

     

    

    EXECUTIVE DEFERRED COMPENSATION PLAN

     

      

    OF 2005

     

      

    (As amended and restated effective December 20, 2018)

     

    

    
      
        

    

    
    TABLE OF CONTENTS

     

      

    	 	 	
            PAGE

          
	
            1.

          	
            PURPOSE

          	
            1

          
	
            2.

          	
            DEFINITIONS

          	
            1

          
	 	
            2.1

          	
            Accounting Date.

          	
            1

          
	 	
            2.2

          	
            Base Compensation.

          	
            1

          
	 	
            2.3

          	
            Basic Company Credit.

          	
            1

          
	 	
            2.4

          	
            Beneficiary.

          	
            2

          
	 	
            2.5

          	
            Board.

          	
            2

          
	 	
            2.6

          	
            Bonus Compensation.

          	
            2

          
	 	
            2.7

          	
            Business Day.

          	
            2

          
	 	
            2.8

          	
            Cigna.

          	
            2

          
	 	
            2.9

          	
            Closing.

          	
            2

          
	 	
            2.10

          	
            Code.

          	
            2

          
	 	
            2.11

          	
            Committee.

          	
            2

          
	 	
            2.12

          	
            Common Stock.

          	
            2

          
	 	
            2.13

          	
            Common Stock Fund.

          	
            3

          
	 	
            2.14

          	
            Company.

          	
            3

          
	 	
            2.15

          	
            Company Credits.

          	
            3

          
	 	
            2.16

          	
            Compensation.

          	
            3

          
	 	
            2.17

          	
            Compensation Account(s).

          	
            3

          
	 	
            2.18

          	
            Credit Date.

          	
            3

          
	 	
            2.19

          	
            Deferred Bonus.

          	
            3

          
	 	
            2.20

          	
            Deferred Compensation.

          	
            3

          
	 	
            2.21

          	
            Disability.

          	
            4

          
	 	
            2.22

          	
            Effective Date.

          	
            4

          
	 	
            2.23

          	
            Election.

          	
            4

          
	 	
            2.24

          	
            Employee.

          	
            4

          
	 	
            2.25

          	
            Fair Market Value.

          	
            4

          
	 	
            2.26

          	
            In-Service Account.

          	
            4

          
	 	
            2.27

          	
            Merger Agreement

          	
            5

          
	 	
            2.28

          	
            Newly Eligible Participant.

          	
            5

          
	 	
            2.29

          	
            Participant.

          	
            5

          
	 	
            2.30

          	
            Past Service Credit.

          	
            5

          
	 	
            2.31

          	
            Plan.

          	
            5

          
	 	
            2.32

          	
            Plan Year.

          	
            5

          
	 	
            2.33

          	
            Retirement.

          	
            5

          
	 	
            2.34

          	
            Retention Account.

          	
            5

          
	 	
            2.35

          	
            Retention Agreement.

          	
            5

          
	 	
            2.36

          	
            Retention Credit

          	
            6

          
	 	
            2.37

          	
            Retirement Account.

          	
            6

          
	 	
            2.38

          	
            Service Year.

          	
            6

          
	 	
            2.39

          	
            Special Bonus.

          	
            6

          
	 	
            2.40

          	
            Stock Unit(s).

          	
            6

          
	 	
            2.41

          	
            Termination.

          	
            6

          

    

    

    
      i

      
        

    

    	
            3.

          	
            ADMINISTRATION

          	
            6

          
	
            4.

          	
            ELIGIBILITY

          	
            7

          
	
            5.

          	
            PARTICIPANT ACCOUNTS

          	
            7

          
	
            6.

          	
            ELECTION TO PARTICIPATE

          	
            8

          
	 	
            6.1

          	
            In General.

          	
            8

          
	 	
            6.2

          	
            Investment Alternatives For Existing Balances.

          	
            10

          
	
            7.

          	
            COMPANY CREDITS AND SPECIAL AND DEFERRED BONUSES

          	
            10

          
	 	
            7.1

          	
            Vesting.

          	
            10

          
	 	
            7.2

          	
            Forfeiture.

          	
            11

          
	
            8.

          	
            DISTRIBUTION

          	
            11

          
	 	
            8.1

          	
            Retirement Account.

          	
            11

          
	 	
            8.2

          	
            In-Service Account.

          	
            11

          
	 	
            8.3

          	
            Termination or Disability.

          	
            12

          
	 	
            8.4

          	
            Death.

          	
            12

          
	 	
            8.5

          	
            Retention Accounts.

          	
            12

          
	 	
            8.6

          	
            Form of Distribution.

          	
            12

          
	
            9.

          	
            FINANCIAL HARDSHIP

          	
            13

          
	
            10.

          	
            BENEFICIARY DESIGNATION

          	
            14

          
	
            11.

          	
            UNSECURED GENERAL CREDITOR STATUS OF EMPLOYEE

          	
            14

          
	
            12.

          	
            SHARES; ADJUSTMENTS IN EVENT OF CHANGES IN CAPITALIZATION

          	
            14

          
	
            13.

          	
            INALIENABILITY OF BENEFITS

          	
            15

          
	
            14.

          	
            CLAIMS PROCEDURE

          	
            15

          
	
            15.

          	
            GOVERNING LAW

          	
            18

          
	
            16.

          	
            AMENDMENTS

          	
            18

          
	
            17.

          	
            TIME FOR PAYMENT

          	
            18

          

    

    

    
      ii

      
        

    

    
    
      EXPRESS SCRIPTS, INC.

      

      

      EXECUTIVE DEFERRED COMPENSATION PLAN OF 2005

      

      

      1.            PURPOSE

      

      

      The purpose of this Express Scripts, Inc. Executive Deferred Compensation Plan of 2005 (the “Plan”) is to provide eligible key employees of the Company with
          an opportunity to defer compensation to be earned by them from the Company as a means of saving for retirement or other future purposes and to provide such employees with competitive retirement and capital accumulation benefits.  In addition, the
          Plan is intended to provide eligible key employees additional incentive to remain employed by the Company and to attract certain executive-level employees.

      

      

      Express Scripts, Inc. previously adopted the Express Scripts, Inc. Executive Deferred Compensation Plan, as amended and restated effective January 1, 2003
          (“Prior Plan”).  Effective December 31, 2004, Express Scripts, Inc. amended the Prior Plan to cease future deferrals thereunder after December 31, 2004, and the Prior Plan is intended to be grandfathered for purposes of Section 409A of the Code. 
          Effective January 1, 2005, Express Scripts, Inc. set forth in a separate document the terms of the Plan, which apply to amounts deferred or that first become vested hereunder after December 31, 2004.  Express Scripts Holding Company then assumed,
          amended and restated the Plan on April 2, 2012 and further amended the Plan in April and November 2018, respectively.  This document reflects Cigna’s assumption, amendment and restatement of the Plan effective as of December 20, 2018.  The Plan
          and the Prior Plan shall continue to be set forth in separate documents, and this amendment and restatement of the Plan does not amend the Prior Plan that is intended to be grandfathered for purposes of Section 409A of the Code.  The Prior Plan
          and the Plan shall be considered one plan set forth in two separate documents.

      

      

      2.            DEFINITIONS

      

      

      The following definitions shall be applicable throughout the Plan:

      

      

      2.1         Accounting Date.

      

      

      “Accounting Date” means each Business Day on which a calculation concerning a Participant’s Compensation Account is performed, or as otherwise defined by
          the Committee.

      

      

      2.2         Base Compensation.

      

      

      “Base Compensation” means Compensation other than Bonus Compensation.

      

      

      2.3         Basic Company Credit.

      

      

      “Basic Company Credit” means an amount, if any, credited to a Participant’s Retirement Account as described in Section 7.

      

      

      
        1

        
          

      

      2.4         Beneficiary.

      

      

      “Beneficiary” means the person or persons designated by the Participant in accordance with Section 10, or if no person or persons are so designated, the
          estate of a deceased Participant.

      

      

      2.5         Board.

      

      

      “Board” means the Board of Directors of Express Scripts Holding Company or its designee; provided that at and following the Closing “Board” shall mean the
          Board of Directors of Cigna or its designee.

      

      

      2.6         Bonus Compensation.

      

      

      “Bonus Compensation” means payments under the Company’s Annual Bonus Plan or any successor thereto to the extent such payments constitute “performance-based
          compensation” within the meaning of Treas. Reg. Section 1.409A-1(e). To the extent that a portion of a payment under the Company’s Annual Bonus Plan does not constitute “performance-based compensation”, such portion shall be considered Base
          Compensation and any Election that relates to Base Compensation will apply to such portion.

      

      

      2.7         Business Day.

      

      

      “Business Day” means a day on which the Nasdaq Global Select Market is open for trading activity.

      

      

      2.8         Cigna.

      

      

      “Cigna” means Cigna Corporation, a Delaware corporation, and, where context requires, each of its subsidiaries.

      

      

      2.9         Closing.

      

      

      “Closing” means the consummation of the transactions contemplated by the Merger Agreement.

      

      

      2.10       Code.

      

      

      “Code” means the Internal Revenue Code of 1986, as amended.

      

      

      2.11       Committee.

      

      

      “Committee” means the Compensation Committee of the Board or its designee.

      

      

      2.12       Common Stock.

      

      

      “Common Stock” means the common stock, $0.01 par value, of Express Scripts Holding Company or, at and following the Closing, the common stock, $0.01 par
          value, of Cigna, and any securities into which such common stock is converted in a merger, recapitalization or similar transaction.

      

      

      
        2

        
          

      

      2.13       Common Stock Fund.

      

      

      “Common Stock Fund” means that investment option, approved by the Committee, in which a Participant’s Compensation Accounts may be deemed to be invested and
          may earn income (or incur losses) based on a hypothetical investment in Common Stock (including notional interests resulting from the provisions of the Merger Agreement).

      

      

      2.14       Company.

      

      

      “Company” means Express Scripts Holding Company, its divisions, subsidiaries and affiliates.   Following the Closing, Cigna shall be an affiliate of Express
          Scripts Holding Company solely with respect to those Employees who were eligible to participate in the Plan immediately prior to the Closing.

      

      

      2.15       Company Credits.

      

      

      “Company Credits” means amounts credited as either Basic Company Credits or Past Service Credits by the Company to Compensation Accounts, in the sole
          discretion of the Committee, pursuant to Section 7.

      

      

      2.16       Compensation.

      

      

      “Compensation” means all (a) salary, commissions, payments under the Company’s Annual Bonus Plan (but not expense or other reimbursement or allowances)
          currently payable by the Company to a Participant and (b) compensation in the form of Common Stock which the Employee may elect to convert to Stock Units if permitted by, and in accordance with, the terms of the grant of such compensation.  For
          purposes of this Plan, the Committee may determine the amounts that will be considered Compensation with respect to any Participant.

      

      

      2.17       Compensation Account(s).

      

      

      “Compensation Account(s)” means the Retirement Account, the In-Service Account and/or the Retention Account.

      

      

      2.18       Credit Date.

      

      

      “Credit Date” means each date on which Deferred Compensation is credited to Compensation Accounts in accordance with rules prescribed by the Committee.

      

      

      2.19       Deferred Bonus.

      

      

      “Deferred Bonus” means an amount, if any, designated as such by the Committee and credited to a Participant’s Compensation Account.

      

      

      2.20       Deferred Compensation.

      

      

      “Deferred Compensation” means the Compensation elected by the Participant to be deferred pursuant to the Plan.

      

      

      
        3

        
          

      

      2.21       Disability.

      

      

      “Disability” means the Participant (a) is unable to engage in any substantial gainful activity by reason of any medically determinable physical or mental
          impairment that can be expected to result in death or can be expected to last for a continuous period of not less than 12 months, or (b) is, by reason of any medically determinable physical or mental impairment which can be expected to result in
          death or can be expected to last for a continuous period of not less than 12 months, receiving income replacement benefits for a period of not less than 3 months under an accident and health plan covering employees of the Company.

      

      

      2.22       Effective Date.

      

      

      “Effective Date” means the effective date of the Plan, January 1, 2005.

      

      

      2.23       Election.

      

      

      “Election” means a Participant’s delivery of a written notice of election to the Committee or its designee electing to defer payment of a specified
          percentage of his or her Compensation (in accordance with rules prescribed by the Committee), either until Retirement, death or such other time as further permitted by the Committee.

      

      

      2.24       Employee.

      

      

      “Employee” means an individual classified by the Committee as a full-time, regular salaried employee of the Company.

      

      

      2.25       Fair Market Value.

      

      

      “Fair Market Value” means, as of any specified date, the closing sales price of a share of Common Stock, as reported on the Nasdaq Global Select Market on
          that date (or, if there are no sales on that date, the last preceding date on which there was a sale), or, in the event the Common Stock is listed on a different principal established stock exchange, the closing sales price of a share of Common
          Stock, as reported on such exchange on that date (or, if there are no sales on that date, the last preceding date on which there was a sale).  In the absence of any listing of the Common Stock on the Nasdaq Global Select Market or on any
          established stock exchange, Fair Market Value means the fair market value of the Common Stock on any specified date as determined in good faith by the Committee.

      

      

      2.26       In-Service Account.

      

      

      “In-Service Account” means the account or accounts to which a Participant elects to contribute Deferred Compensation and, to the extent permitted in an
          award as described in Section 5, Special Bonuses and/or Deferred Bonuses, and from which, pursuant to Section 8.2, distributions are made.  The portion of any In-Service Account which was not vested under the Prior Plan as of December 31, 2004
          shall be hypothetically transferred and credited to the In-Service Account under this Plan and shall be subject to the vesting provisions hereunder from the date first credited under the Prior Plan.

      

      

      
        4

        
          

      

      2.27       Merger Agreement

      

      

      “Merger Agreement” means that certain Agreement and Plan of Merger dated March 8, 2018, by and among the Company, Cigna and certain other parties.

      

      

      2.28       Newly Eligible Participant.

      

      

      “Newly Eligible Participant” shall mean an Employee who has been determined eligible to participate in the Plan for the first time during the applicable
          Plan Year or an Employee who has experienced a Termination and is re-hired and becomes eligible to participate in the Plan again whether during the same Plan Year or a subsequent Plan Year.

      

      

      2.29       Participant.

      

      

      “Participant” means an Employee selected by the Committee to be eligible to participate in the Plan.

      

      

      2.30       Past Service Credit.

      

      

      “Past Service Credit” means an amount, if any, credited to a Participant’s Retirement Account as described in Section 7.

      

      

      2.31       Plan.

      

      

      “Plan” means this Express Scripts, Inc. Executive Deferred Compensation Plan of 2005, as amended from time to time.

      

      

      2.32       Plan Year.

      

      

      “Plan Year” means the annual period commencing January 1 and ending the following December 31.

      

      

      2.33       Retirement.

      

      

      “Retirement” means a Participant’s termination of employment after attaining age 55 and having a combination of full years of age plus Service Years
          totaling at least 65.

      

      

      2.34       Retention Account.

      

      

      “Retention Account” means the account to which Retention Credits are posted and from which, pursuant to the terms and conditions of the applicable Retention
          Agreement, distributions are made.

      

      

      2.35       Retention Agreement.

      

      

      “Retention Agreement” means the retention agreement entered into by an Employee and Cigna, effective and conditioned upon the Closing, which sets forth the
          amount of the Retention Credit.

      

      

      
        5

        
          

      

      2.36       Retention Credit

      

      

      “Retention Credit” means the amount of the “Deferred Compensation Account” (as such term is defined in the applicable Retention Agreement) specified in the
          respective Participant’s Retention Agreement which shall be credited to the applicable Participant’s Retention Account.

      

      

      2.37       Retirement Account.

      

      

      “Retirement Account” means the account to which a Participant elects to contribute Deferred Compensation and to which Company Credits, Special Bonuses
          and/or Deferred Bonuses (subject to any election described in Section 5) are made, and from which, pursuant to Section 8.1, distributions are made.  The portion of any Retirement Account which was not vested under the Prior Plan as of December
          31, 2004 shall be hypothetically transferred and credited to the Retirement Account under this Plan and shall be subject to the vesting provisions hereunder from the date first credited under the Prior Plan.

      

      

      2.38       Service Year.

      

      

      “Service Year” means, as designated by the Committee, such year or portion thereof during which the services have been rendered by a Participant for which
          Compensation is payable.

      

      

      2.39       Special Bonus.

      

      

      “Special Bonus” means an amount, if any, designated as such by the Committee and credited to a Participant’s Compensation Account.

      

      

      2.40       Stock Unit(s).

      

      

      “Stock Unit(s)” means the share equivalents credited to the Common Stock Fund of a Participant’s Compensation Account in accordance with Sections 5, 6 and
          7.

      

      

      2.41       Termination.

      

      

      “Termination” means termination of services as an Employee for any reason other than Retirement.  Such determination of whether a Termination has occurred
          shall be made in a manner consistent with Section 409A of the Code and the regulations and other guidance issued thereunder to avoid adverse tax consequences thereunder.

      

      

      3.            ADMINISTRATION

      

      

      Full power and authority to construe, interpret and administer the Plan shall be vested in the Committee.  This power and authority includes, but is not
          limited to, selecting which Employees are eligible to participate in the Plan, selecting Compensation eligible for deferral, selecting investment indices, establishing the level of Company Credits (if any) to the Plan, establishing deferral terms
          and conditions, receiving and approving beneficiary designation forms, and adopting modifications, amendments and procedures as may be deemed necessary, appropriate or convenient by the Committee.  Decisions of the Committee shall be final,
          conclusive and binding upon all parties.  The Committee, in its sole discretion, may delegate day-to-day administration of the Plan to an employee or employees of the Company or to a third-party administrator.  Any such employee or employees of
          the Company or third-party administrator delegated the day-to-day administration of the Plan by the Committee shall be referred to as the “Plan Administrator.”  The Committee may also rely on outside counsel, independent accountants or other
          consultants or advisors for advice and assistance in fulfilling its administrative duties under the Plan.

      

      

      
        6

        
          

      

      4.            ELIGIBILITY

      

      

      Employees at the vice-president level or higher shall be eligible to participate in the Plan commencing on the first date they are employed by the Company
          in such capacity; provided that if such date is on or after November 1 in any Plan Year or if such Employee already participates in a deferred compensation arrangement that would be aggregated with this Plan for purposes of Section 409A of the
          Code and the regulations and guidance issued thereunder, such Employee shall not be eligible to participate in the Plan until the following January 1.  Employees of Cigna or former employees of Cigna who are transferred from Cigna to the Company
          following the Closing shall not be eligible to participate in the Plan.  For the avoidance of doubt, Employees who are eligible to participate in the Plan as of immediately prior to the Closing shall remain eligible to participate in the Plan so
          long as they are an Employee, even if they experience a transfer of employment to Cigna following the Closing.

      

      

      Employees who have entered into Retention Agreements which provide for Retention Credits shall be eligible to participate in the Plan pursuant to the terms
          and conditions established by the Committee.

      

      

      The Committee shall have the ability to impose restrictions on the eligibility of new Employees as it considers appropriate.

      

      

      5.            PARTICIPANT

              ACCOUNTS

      

      

      Upon a Participant’s initial election to participate in the Plan, there shall be established a Retirement Account and an In-Service Account, as designated
          by the Participant, to which there shall be credited any Deferred Compensation on or after January 1, 2005 with respect to services performed subsequent to such election as of each Credit Date.  In addition, Company Credits, if any, made pursuant
          to Section 7 shall be allocated to a Participant’s Retirement Account in accordance with rules prescribed by the Committee.  Retention Credits shall be credited to the applicable Participant’s Retention Account in accordance with the rules
          prescribed by the Committee and in accordance with the terms of the applicable Retention Agreement.  Each such Compensation Account shall be credited (or debited) on each Accounting Date with income (or loss) based upon a hypothetical investment
          in any one or more of the investment options available under the Plan, as prescribed by the Committee for the particular Compensation credited, which may include a Common Stock Fund.  A Participant may make separate investment elections for each
          type of Compensation Account (one with respect to his or her Retirement Account, one with respect to his or her In-Service Accounts and, if applicable, one with respect to his or her Retention Account); provided, however, that earnings and losses
          on Deferred Compensation and/or Retention Credits, as applicable, which relates to Compensation which would have been paid (absent the Election) in Common Stock shall initially be measured by reference to a hypothetical investment in the Common
          Stock Fund and shall be further subject to the terms of the grant of such Compensation.

      

      

      
        7

        
          

      

      A Participant’s Special Bonus and/or Deferred Bonus, if any, to the extent not yet deferred and vested under the Prior Plan as of December 31, 2004, shall
          be credited to the Participant’s Retirement Account, unless the Agreement or award providing for such bonus(es) provides that the Participant may elect to credit any or all of such amounts to his or her In-Service Account and the Participant so
          elects prior to the Plan Year in which such bonus(es) is earned and otherwise in accordance with rules prescribed by the Committee.

      

      

      Each Participant at any time may have no more than two In-Service Accounts under this Plan and the Prior Plan, in the aggregate.

      

      

      If all or any portion of a Participant’s Compensation Account(s) is measured by a hypothetical investment in the Common Stock Fund, that portion of the
          Participant’s Compensation Account(s) shall be credited on the first day of the calendar quarter following each Credit Date with Stock Units equal to the number of shares of Common Stock (including fractions of a share) that could have been
          purchased with the amount of such Deferred Compensation and/or Retention Credits, as applicable, (plus earnings and less losses determined in accordance with the next sentence) at the Fair Market Value on such first day of such calendar quarter. 
          For the period between such Credit Date and the first day of such calendar quarter, earnings and losses shall be measured by reference to a hypothetical investment selected by the Committee.  As of any date for the payment of cash dividends on
          the Common Stock, the portion of the Participant’s Compensation Account(s) invested in the Common Stock Fund as of the dividend record date shall be credited with additional Stock Units calculated by dividing (i) the product of (a) the dollar
          value of the dividend declared in respect of a share of Common Stock multiplied by (b) the number of Stock Units credited to the Participant’s Compensation Account(s) as of the dividend record date by (ii) the Fair Market Value of a share of
          Common Stock on the dividend payment date.

      

      

      6.            ELECTION

              TO PARTICIPATE

      

      

      6.1         In General.

      

      

      Any Employee selected by the Committee to participate in the Plan may elect to do so by delivering to the Committee or its designee an Election on a form
          prescribed by the Committee, designating the Compensation Account to which the Deferred Compensation is to be credited, electing the timing and form of distribution (if applicable), and setting forth the manner in which such Deferred Compensation
          shall be invested in accordance with Section 5.  A Participant’s initial Election must be filed at such time as designated by the Committee, but in no event later than the day immediately preceding the first day of the Plan Year to which such
          Election relates.  A Participant may submit a new Election for any subsequent year in order to change the election previously made.  Such subsequent Election must be filed at such time as designated by the Committee, but in no event later than 15
          days preceding the first day of the Plan Year to which such subsequent Election relates.  If a specific election has not been made with respect to any Plan Year, the Election (if any) effective with respect to the immediately preceding Plan Year
          shall remain in effect.  An effective Election may not be revoked or modified during a Plan Year with respect to that Plan Year.

      

      

      
        8

        
          

      

      Subject to Section 4, newly employed or eligible Employees who are eligible to participate in the Plan may elect to participate for the current Plan Year
          within the first 30 days after commencing employment or becoming eligible.  Such election shall be effective on the first day of the month following the end of such 30-day period and shall apply only with respect to Compensation earned after the
          effective date of such election.  Elections for subsequent Plan Years shall be made in accordance with the preceding paragraph.

      

      

      An Employee who is party to a Retention Agreement shall be deemed to be a Participant in the Plan.  Upon the establishment of a Retention Account, the
          Participant may select his or her investment elections, which shall apply to all amounts credited to such Retention Account, consistent with the terms and conditions determined by the Committee.

      

      

      Notwithstanding anything in this Section 6.1, Section 4 or otherwise in the Plan to the contrary, beginning with the 2019 Plan Year:

      

      

      (i)          A Participant who is not a Newly Eligible Participant
          shall make separate Elections with respect to Base Compensation and Bonus Compensation. For Elections relating to Base Compensation, the Election must be filed no later than the day immediately preceding the first day of the Plan Year to which
          such Election relates. For Elections relating to Bonus Compensation, the Election must be filed no later than six months before the end of the performance period for which the Bonus Compensation is earned (and in no event later than the date on
          which the amount of the Bonus Compensation becomes readily ascertainable); and

      

      

      (ii)         A Newly Eligible Participant who is eligible to
          participate in the Plan may elect to participate for the current Plan Year within the first 30 days after commencing employment or becoming eligible. Such election shall be effective on the first day of the month following the end of such 30-day
          period and shall apply only to Base Compensation earned after the effective date of such Election. A Newly Eligible Participant is not eligible to make an election with respect to Bonus Compensation in his or her first year of eligibility or
          re-eligibility to participate in the Plan. Elections relating to both Base Compensation and Bonus Compensation for subsequent Plan Years shall be made in accordance with the paragraph above; and

      

      

      (iii)        Nothing herein (or otherwise in the Plan) shall be
          construed to limit the Committee (or to the extent delegated, its delegate’s) ability to impose further restrictions on any Participant’s (including, for the avoidance of doubt any Newly Eligible Participant’s) ability to make elections under the
          Plan as it considers appropriate.

      

      

      If a specific election has not been made with respect to any Plan Year, the Election (if any) effective with respect to the immediately preceding Plan Year
          shall remain in effect.

      

      

      For the avoidance of doubt, any deferral election in effect under the Plan immediately prior to this amendment and restatement shall continue and be
          recognized as an Election hereunder for the year or other applicable period to which it relates.  In addition, the amount deemed credited to an account under the Plan immediately prior to this amendment and restatement shall be credited to the
          applicable Compensation Account(s) hereunder.

      

      

      
        9

        
          

      

      6.2         Investment Alternatives For Existing Balances.

      

      

      A Participant may elect to change an existing selection as to the investment alternatives in effect with respect to an existing Compensation Account (in
          increments prescribed by the Committee) as often, and with such restrictions, as determined by the Committee.

      

      

      7.            COMPANY

              CREDITS AND SPECIAL AND DEFERRED BONUSES

      

      

      In the sole discretion of the Committee, in a given Plan Year the Company may credit a specified percentage of a Participant’s Compensation to the
          Participant’s Retirement Account as a Basic Company Credit.  The Committee, in its sole discretion, may cause the Company to credit such Basic Company Credit for all or any portion of the Participants in the Plan in such Plan Year.  Further, the
          Committee may cause the Company to credit a Deferred Bonus and/or a Special Bonus to recognize significant efforts by Plan Participants as the Committee, in its sole discretion, deems appropriate.  In addition, the Committee may cause the Company
          to credit a Past Service Credit to recognize past service as the Committee, in its sole discretion, deems appropriate.  Such Basic Company Credit, Past Service Credit, Special Bonus and Deferred Bonus, if any, shall be credited to a Participant’s
          Retirement Account (except as provided in any election described in Section 5) and shall be subject to the limitations determined appropriate by the Committee, including the limitation contained in Section 8.3 and the limitations described below
          in this Section 7.

      

      

      7.1         Vesting.

      

      

      A Participant’s Deferred Compensation shall be immediately one-hundred percent (100%) nonforfeitable upon being credited to such Participant’s Retirement or
          In-Service Account; provided, however, that Deferred Compensation which relates to restricted shares of Common Stock shall vest in accordance with the terms of the restricted stock agreement to which they relate.

      

      

      A Participant’s Basic Company Credit for a Plan Year shall become nonforfeitable three (3) years after the end of the Plan Year to which such Basic Company
          Credit relates.

      

      

      A Participant’s Past Service Credit shall be fifty-percent (50%) nonforfeitable upon being credited to his or her Retirement Account.  The remaining
          fifty-percent (50%) shall become nonforfeitable as follows: one (1) year after the end of the Plan Year in which the Past Service Credit is credited to the Participant’s Retirement Account, the Participant shall be one-third (1/3) vested in the
          remaining fifty percent (50%); two (2) years after the end of the Plan Year in which the Past Service Credit is credited to the Participant’s Retirement Account, the Participant shall be two-thirds (2/3) vested in the remaining fifty percent
          (50%); and three (3) years after the end of the Plan Year in which the Past Service Credit is credited to the

      

      

      Participant’s Retirement Account, the Participant shall be one-hundred percent (100%) vested in the remaining fifty percent (50%).  A Participant’s Special
          Bonus and/or Deferred Bonus shall become vested in accordance with the terms of the Agreement or award providing for such bonus(es).

      

      

      Except with respect to Retention Credits, upon a Participant’s Termination for any reason other than death, Disability or Retirement, he or she shall
          forfeit any nonvested benefits.  Except as otherwise provided in an award, a Participant shall have a one-hundred percent (100%) nonforfeitable right to Basic Company Credits, Past Service Credits, Special Bonuses and Deferred Bonuses upon
          becoming eligible for Retirement or upon Termination due to death or Disability.

      

      

      
        10

        
          

      

      For the avoidance of doubt, amounts credited under this Plan prior to April 2, 2012 shall be subject to the vesting and forfeiture provisions of this Plan
          after such date.

      

      

      Amounts credited to this Plan with respect to any Retention Credit shall vest, if applicable, in accordance with the terms and conditions set forth in the
          applicable Retention Agreement.

      

      

      7.2         Forfeiture.

      

      

      Upon a Participant’s Termination or Retirement, the Company reserves the right to withhold payment of a portion of a Participant’s Retirement Account
          attributable to Basic Company Credits, Past Service Credits, Special Bonuses and/or Deferred Bonuses made under Section 7 (and earnings thereon) in the event the Committee determines that the Participant has violated the Company’s standard
          noncompetition and nondisclosure agreement or any other employment agreement executed by the Participant, or otherwise acts against the interests of the Company, as determined by the Committee in its sole discretion.  Forfeiture of any Retention
          Credit or portion thereof, if applicable, shall be determined in accordance with the terms and conditions of the applicable Retention Agreement.

      

      

      8.            DISTRIBUTION

      

      

      8.1         Retirement Account.

      

      

      In the event of a Participant’s Retirement, the Participant’s Retirement Account shall be distributed at the time and in the manner elected by the
          Participant in his or her Election.  If no Election is made by a Participant as to the timing of distribution or form of payment of his or her Retirement Account, upon the Participant’s Retirement such account shall be paid in a single lump sum. 
          A Participant may change this election to provide for a later distribution date; provided, that such election is filed in accordance with rules established by the Committee, and (a) such election shall not take effect until at least 12 months
          after the date on which such election is properly filed, (b) the first payment with respect to which such election is made shall be deferred for a period of not less than 5 years from the date such payment would otherwise have been made, and (c)
          any election related to a payment that was otherwise to be made at a specified time may not be made less than 12 months prior to the date of the first scheduled payment.  Subject to the foregoing, the Election most recently accepted by the
          Committee shall govern the payout of any benefits under a Retirement Account under the Plan.

      

      

      8.2         In-Service Account.

      

      

      Deferred Compensation, Special Bonuses and/or Deferred Bonuses credited to a Participant’s In-Service Account shall be distributed at the time and in the
          manner elected by the Participant in his or her Election.  A Participant may extend the deferral period by notifying the Company in accordance with the terms of the Plan and procedures established by the Committee.  A previously elected deferral
          period for an In-Service Account may be extended only one time; provided, that such election is filed in accordance with rules established by the Committee, and (a) such election shall not take effect until at least 12 months after the date on
          which such election is properly filed, (b) the first payment with respect to which such election is made shall be deferred for a period of not less than 5 years from the date such payment would otherwise have been made, and (c) any election
          related to a payment that was otherwise to be made at a specified time may not be made less than 12 months prior to the date of the first scheduled payment.  Subject to the foregoing, the Election most recently accepted by the Committee shall
          govern the payout of any benefits under an In-Service Account under the Plan.

      

      

      
        11

        
          

      

      8.3         Termination or Disability.

      

      

      In the event of a Participant’s Termination or Disability, the Participant’s vested Retirement and/or In-Service Accounts shall be distributed in a single
          lump sum to such Participant 30 days after his or her Termination or Disability.  Upon Termination, all unvested amounts under any Retirement and/or In-Service Accounts shall be immediately forfeited and removed from such Compensation Accounts.

      

      

      8.4         Death.

      

      

      In the event of the Participant’s death (a) while in the employment of the Company or (b) after the Participant’s Termination but prior to the payment of
          such Participant’s Retirement and/or In-Service Accounts pursuant to Section 8.3, the Company shall pay the following amounts to the Participant’s Beneficiary in a single lump sum 30 days after the Participant’s date of death:

      

      

      (1)       the remaining amounts, if any, in a Participant’s
          In-Service Account; and

      

      

      (2)       the amounts in the Participant’s Retirement Account.

      

      

      In the event of the Participant’s death following Retirement, the Company shall pay the amount in the Participant’s Retirement Account to the Participant’s
          Beneficiary in the form and at the time elected by the Participant pursuant to Section 6.1.

      

      

      8.5         Retention Accounts.

      

      

      Notwithstanding anything in the Plan to the contrary, funds from a Retention Account shall be distributed in accordance with the terms and conditions of the
          applicable Retention Agreement.

      

      

      8.6         Form of Distribution.

      

      

      Distribution of a Participant’s Compensation Accounts shall be made in cash; provided that, any amounts in a Participant’s Compensation Accounts (other than
          a Participant’s Retention Account) invested in the Common Stock Fund shall be distributed to the Participant in whole shares of Common Stock with fractional shares paid in cash.  Distribution of a Participant’s Retention Account shall be made in
          cash in all cases and regardless of whether all or any portion of such Retention Account is invested in the Common Stock Fund.

      

      

      
        12

        
          

      

      When required, the Company shall withhold from any distribution of cash or Common Stock to a Participant or other person under this Plan an amount
          sufficient to cover any required withholding taxes, including the Participant’s social security and Medicare taxes (FICA) and federal, state and local income tax with respect to income arising from payment of the Award.  The Company shall have
          the right to require the payment of any such taxes before issuing any Common Stock comprising a part of such distribution.  In lieu of all or any part of a cash payment from a person receiving Common Stock under this Plan, the Committee may
          permit a person to cover all or any part of the required withholdings, and to cover any additional withholdings up to the amount needed to cover the person’s full FICA and federal, state and local income tax with respect to income arising from
          payment the Common Stock portion of such distribution, through a reduction of the numbers of shares of Common Stock delivered to such person or a delivery or tender to the Company of other shares of Common Stock held by such person, in each case
          valued in the same manner as used in computing the withholding taxes under applicable laws.

      

      

      9.            FINANCIAL

              HARDSHIP

      

      

      Upon the written request of a Participant or a Participant’s legal representative and a finding that continued deferral will result in an unforeseeable
          financial emergency to the Participant, the Committee (in its sole discretion) may authorize (a) the payment of all or a part of a Participant’s Compensation Accounts representing Deferred Compensation and earnings thereon in a single lump sum
          prior to his or her ceasing to be a Participant, or (b) a Participant to cease contributing Deferred Compensation to the Plan during a Plan Year.  It is intended that the Committee’s determinations as to whether the Participant has suffered an
          “unforeseeable financial emergency” shall be made consistent with the requirements under Section 409A of the Code and the regulations and guidance thereunder.  An “unforeseeable financial emergency” means a severe financial hardship to the
          Participant, the Participant’s spouse, the Participant’s beneficiary or the Participant’s dependent (as defined in Code Section 152, without regard to Sections 152(b), (b)(2) and (d)(1)(B)); loss of the Participant’s property due to casualty; or
          other similar extraordinary and unforeseeable circumstances arising as a result of events beyond the control of the Participant.  Any amounts distributed with respect to an emergency shall not exceed the amounts necessary to satisfy such
          emergency plus amounts necessary to pay taxes reasonably anticipated as a result of the distribution, after taking into account the extent to which such hardship is or may be relieved by the cancellation of the Participant’s deferral election
          under this Plan or through reimbursement or compensation by insurance or otherwise or by liquidation of the Participant’s assets (to the extent the liquidation of such assets would not itself cause severe financial hardship).  The Committee may
          adopt procedures for determining when a hardship situation exists, including the use of independent advisors to make such determinations.

      

      

      Any Participant receiving a hardship distribution may have no further amounts deferred pursuant to an Election under this Plan for a period of one year from
          the date of such distribution, and any subsequent deferral Election may only begin at the beginning of a subsequent Plan Year and in accordance with the procedures in Section 6.  The Participant shall not repay to the Company amounts distributed
          pursuant to this Section 9.

      

      

      10.          BENEFICIARY

              DESIGNATION

      

      

      A Participant may designate one or more persons (including a trust) to whom or to which payments are to be made if the Participant dies before receiving
          distribution of all amounts due under the Plan.  A Beneficiary designation made under the Prior Plan shall apply to this Plan, unless subsequently changed as provided herein.  A Participant may, at any time, elect to change the designation of a
          Beneficiary.  A designation of Beneficiary will be effective only after the signed designation of Beneficiary is filed with the Committee or its designee while the Participant is alive and will cancel all designations of Beneficiary signed and
          filed earlier, including any designations of Beneficiary made under the Prior Plan.  If the Participant fails to designate a Beneficiary as provided above or if all of a Participant’s Beneficiaries predecease him or her and he or she fails to
          designate a new Beneficiary, the remaining unpaid amounts shall be paid in one lump sum to the estate of such Participant.  If all Beneficiaries of the Participant die after the Participant but before complete payment of all amounts due
          hereunder, the remaining unpaid amounts shall be paid in one lump sum to the estate of the last to die of such Beneficiaries.

      

      

      
        13

        
          

      

      11.          UNSECURED

              GENERAL CREDITOR STATUS OF EMPLOYEE

      

      

      The payments to Participants and their Beneficiaries hereunder shall be made from the general corporate assets of the Company.  No person shall have any
          interest in any such assets by virtue of the provisions of this Plan.  The Company’s obligation hereunder shall be an unfunded and unsecured promise to pay money in the future.  To the extent that any person acquires a right to receive payments
          from the Company under the provisions hereof, such right shall be no greater than the right of any unsecured general creditor of the Company; no such person shall have nor acquire any legal or equitable right, interest or claim in or to any
          property or assets of the Company.  Any accounts maintained under this Plan shall be hypothetical in nature and shall be maintained for bookkeeping purposes only.  Neither the Plan nor any account shall hold any actual funds or assets.

      

      

      12.          SHARES;
              ADJUSTMENTS IN EVENT OF CHANGES IN CAPITALIZATION

      

      

      An aggregate of 100,000 split-adjusted shares of common stock of Express Scripts, Inc. were initially allocated to the Prior Plan and reserved for the
          distribution of Compensation Accounts as described in Section 8.6 thereof.  An additional 750,000 shares of Express Scripts, Inc. common stock were subsequently allocated to the Prior Plan, subject to adjustment under Section 12 thereof.  Any
          shares allocated under the terms of the Prior Plan shall be deemed allocated under this Plan since the Prior Plan and this Plan are considered one plan set forth in two separate documents.  Effective April 2, 2012, as a result of the assumption
          of the Plan by Express Scripts Holding Company, the shares of common stock of Express Scripts, Inc. were replaced with shares of Common Stock of the Company and an aggregate of 5,893,208 shares of Common Stock of the Company remained available
          under the Plan, including any shares allocated under the Prior Plan, as adjusted and subject to adjustment hereunder.  The Company may, in its discretion, use shares held in the Treasury under this Plan in lieu of authorized but unissued shares
          of Common Stock.

      

      

      In the event of any change in the outstanding Common Stock of the Company by reason of any stock split, share dividend, recapitalization, merger,
          consolidation, reorganization, combination, or exchange or reclassification of shares, split-up, split-off, spin-off, liquidation or other similar change in capitalization, or any distribution to common shareholders other than cash dividends, the
          number or kind of shares or Stock Units that may be credited under the Plan shall be automatically adjusted so that the proportionate interest of the Participants shall be maintained as before the occurrence of such event.  Such adjustment shall
          be conclusive and binding for all purposes of the Plan.

      

      

      
        14

        
          

      

      13.          INALIENABILITY

              OF BENEFITS

      

      

      The interests of the Participants and their Beneficiaries under the Plan may not in any way be voluntarily or involuntarily transferred, alienated or
          assigned, nor subject to attachment, execution, garnishment or other such equitable or legal process.  A Participant or Beneficiary cannot waive the provisions of this Section 13.

      

      

      14.          CLAIMS
              PROCEDURE

      

      

      Any Participant, Beneficiary or any other person claiming benefits, eligibility, participation or any other right or interest under this Plan may file a
          written claim setting forth the basis of the claim with the Plan Administrator.  A written notice of the Plan Administrator’s disposition of any such claim shall be furnished to the claimant within a reasonable time (not to exceed ninety (90)
          days) after the claim is received by the Plan Administrator.  Notwithstanding the foregoing, the Plan Administrator may have additional time (not to exceed ninety (90) days) to decide the claim if special circumstances exist, provided that he
          advises the claimant, in writing and prior to the end of the initial ninety (90) day period, of the special circumstances giving rise to the need for additional time and the date on which he expects to decide the claim.  If the claim is denied,
          in whole or in part, the notice of disposition shall include the specific reason for the denial, identify the specific provisions of the Plan upon which the denial is based, describe any additional material or information necessary to perfect the
          claim, explain why that material or information is necessary and describe the Plan’s review procedures, including the timeframes thereunder for a claimant to file a request for review and for the Committee to decide the claim.  The notice shall
          also include a statement advising the claimant of his right to bring a civil action if his claim is denied, in whole or in part, upon review.

      

      

      Within sixty (60) days after receiving the written notice of the Plan Administrator’s disposition of the claim, the claimant may request, in writing, review
          by the Committee of the Plan Administrator’s decision regarding his claim.  Upon written request, the claimant shall be entitled to a review meeting with the Committee to present reasons why the claim should be allowed.  The claimant or his
          authorized representative may submit a written statement in support of his claim, together with such comments, information and material relating to the claim, as he deems necessary or appropriate.  The claimant or his duly authorized
          representative shall be provided, upon request and free of charge, reasonable access to, and copies of, all documents, records and other information which are relevant to the claimant’s claim and its review.  If the claimant does not request
          review within sixty (60) days after receiving written notice of the Plan Administrator’s disposition of the claim, the claimant shall be deemed to have accepted the Plan Administrator’s written disposition.

      

      

      The Committee shall make its decision on review and provide written notice thereof to the claimant within a reasonable time (not to exceed sixty (60) days)
          after the claim is received by the Committee.  Notwithstanding the foregoing, the Committee may have additional time (not to exceed sixty (60) days) to decide the claim if special circumstances exist provided that the Committee advises the
          claimant, in writing, prior to the end of the initial sixty (60) day period, of the special circumstances giving rise to the need for additional time and the date on which it expects to decide the claim.  In no event shall the Committee have more
          than one hundred twenty (120) days following its receipt of the claimant’s request for review to provide the claimant with written notice of its decision.  The Committee shall have the right to request of and receive from claimant such additional
          information, documents or other evidence as the Committee may reasonably require.  In the event that the Committee requests such additional information from the claimant, the period for making the benefit determination on review shall not take
          into account the period beginning on the date on which the Committee notifies the claimant in writing of the need for additional information and ending on the date on which the claimant responds to the request for additional information.

      

      

      
        15

        
          

      

      If the claim is denied upon review, in whole or in part, the notice of disposition shall include the specific reason for the denial, identify the specific
          provision of the Plan upon which the denial is based, include a statement advising the claimant of his right to receive, upon written request and free of charge, reasonable access to and copies of all documents, records and other information
          which are relevant to the claimant’s claim and include a statement advising the claimant of his right to bring a civil action under Section 502(a) of the Act if his claim is denied, in whole or in part, upon review.

      

      

      Notwithstanding anything herein, in the case of a benefit contingent on a finding of a Participant’s Disability by the Plan, the provisions of this
          paragraph shall apply.  The Plan will render a determination within forty-five (45) days after its receipt of the claim.  If, prior to the end of such 45-day period, the Plan determines that, due to matters beyond its control, a decision cannot
          be rendered, the period for making the determination may be extended for up to thirty (30) days.  In such case, the Plan shall notify the claimant, prior to the expiration of such 45-day period, of the circumstances requiring an extension and the
          date by which the Plan expects to render a decision.  If, prior to the end of the first 30-day extension period, the Plan determines that, a decision cannot be rendered within that extension period, due to matters beyond its control, the period
          for making the determination may be extended for up to an additional thirty (30) days.  The Plan shall notify the claimant, prior to the expiration of the first 30-day extension period, of the circumstances requiring the extension and the date by
          which the Plan expects to render a decision.  If an extension of time is necessary due to the claimant’s failure to submit all the necessary information, the claimant shall be afforded forty-five (45) days within which to provide the specified
          information.  The period for making the benefit determination shall be tolled from the date on which the Plan sends notification of an extension to the claimant until the date on which the claimant responds to the request for information. Within
          one hundred eighty (180) days after receiving the written notice of an adverse disposition of the claim, the claimant may request in writing, and shall be entitled to, a review of the original disposition.  The decision on appeal will be made by
          a Plan fiduciary who is neither the individual who made the initial disposition nor the subordinate of that individual and no deference will be given to the original disposition. The determination will be based solely on the written record and
          will take into account all comments, documents, records and other information submitted by the claimant relating to the claim and without regard to whether such information was submitted or considered in the initial benefit determination.   If
          the appeal of an adverse Disability determination is based in whole or in part on a medical judgment, the Plan shall consult with a health care professional who has appropriate training and experience in the field of medicine involved in the
          medical judgment.  Such health care professional shall be an individual who is neither an individual who was consulted in connection with the disposition that is the subject of the appeal nor the subordinate of any such individual.  Upon request
          from claimant, the names of the medical or vocational experts whose advice was obtained on behalf of the Plan will be provided without regard to whether their advice was relied upon in making the benefit determination. The claimant will be
          provided with any new or additional evidence considered, relied on, or generated by the Plan in connection with the claim as soon as possible and sufficiently in advance of the deadline by which the Plan must render its decision to allow claimant
          the opportunity to respond to the additional evidence. Before issuing an adverse disposition on appeal based on a new or additional rationale, the Plan shall provide the evidence or rationale to the claimant (free of charge) and allow the
          claimant a reasonable time to respond.  A decision on review shall be rendered in writing by the Plan within a reasonable period of time, but ordinarily not more than forty-five (45) days after receipt of the claimant’s request for review by the
          Plan, unless the Plan determines that special circumstances require an extension of time for processing the claim.  If the Plan determines that an extension is necessary, written notice of the extension shall be furnished to the claimant prior to
          the termination of the initial forty-five (45) period.  In no event shall such extension exceed a period of forty-five (45) days from the end of the initial period.  The extension notice shall indicate the special circumstances requiring an
          extension of time and the date by which the Plan expects to render the determination on review.  If an extension is due to a claimant’s failure to submit information necessary to decide the claim, the claimant shall have forty-five (45) days
          within which to provide the specified information, and the period for making the benefit determination on review shall be tolled from the date on which notification of the extension is sent to the claimant until the date on which the claimant
          responds to the request for additional information. Notification of the adverse disposition of a claim or appeal shall include (i) any internal rules, guidelines, protocols, standards or other similar criterion which was relied upon in making the
          determination or a statement that such rules, guidelines, protocols, standards or similar criteria do not exist; (ii) an explanation of any scientific or clinical judgment for the determination, applying the terms of the Plan to the claimant’s
          medical circumstances, or a statement that such explanation will be provided free of charge upon request, and (iii) a discussion of the decision. If the claimant does not request a review within one hundred eighty (180) days after receiving
          written notice of the original’s disposition of the claim, the claimant shall be deemed to have accepted the original written disposition.

      

      

      
        16

        
          

      

      For purposes of this Section, a document, record or information will be considered “relevant’ if it (a) was relied upon by the Plan Administrator or
          Committee, as applicable, in making the benefit decision, (b) was submitted, considered or generated in the course of making such decision, even if it was not relied upon in making those decisions, or (c) demonstrates compliance with the
          administrative processes and safeguards established by the Plan to insure that the terms of the Plan have been followed and applied consistently.

      

      

      To the extent permitted by law, a decision on review by the Committee shall be binding and conclusive upon all persons whomsoever.  Completion of the claims
          procedure described in this Section shall be a mandatory precondition that must be complied with prior to commencement of a legal or equitable action in connection with the Plan by a person claiming rights under the Plan, or by another person
          claiming rights through such a person.  The Committee may, in its sole discretion, waive these procedures as a mandatory precondition to such an action.

      

      

      
        17

        
          

      

      15.          GOVERNING

              LAW

      

      

      The provisions of this plan shall be interpreted and construed in accordance with the laws of the State of Missouri, except to the extent preempted by
          Federal law.

      

      

      16.          AMENDMENTS

      

      

      The Committee or its designee may amend, alter or terminate this Plan at any time without the prior approval of the Board; provided, however, that the
          Committee or its designee may not, without approval by the Board, materially increase the benefits accruing to Participants under the Plan.

      

      

      17.          TIME
              FOR PAYMENT

      

      

      Notwithstanding anything herein to the contrary, in the event that a Participant is determined to be a specified employee in accordance with Section 409A of
          the Code and the regulations and other guidance issued thereunder for purposes of any payment on termination of employment under this Plan, such payment(s) shall be made or begin, as applicable, on the first payroll date which is more than six
          months following the date of separation from service, to the extent required to avoid the adverse tax consequences to the Participant under Section 409A of the Code.

      

      

      All payments due and payable under the Plan on a fixed date shall be deemed to be made upon such fixed date if such payment is made on such date or a later
          date within the same calendar year or, if later, by the fifteenth day of the third calendar month following the specified date (provided the Participant is not entitled, directly or indirectly, to designate the taxable year of the payment).  In
          addition, a payment is treated as made upon a fixed date under the Plan if the payment is made no earlier than 30 days before the designated payment date and the service provider is not permitted, directly or indirectly, to designate the taxable
          year of the payment.

      

      

      IN WITNESS WHEREOF, this amendment and restatement to the Plan is effective as of December 20, 2018.

       

        

      

      

      
        18

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00290-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00290-of-00352.parquet"}]]