Document:

Exhibit 10.16

 

English Translation

 

The Second Amendment to the Joint Venture Contract relating to the formation of Shanghai Hutchison Pharmaceuticals Limited

 

by and between

 

Shanghai Traditional Chinese Medicine Co., Ltd.

 

Shanghai Hutchison Chinese Medicine (HK) Investment Limited

 

November 5, 2007

 

Shanghai Municipality, China

 

 

THIS SECOND AMENDMENT TO JOINT VENTURE CONTRACT (the “Amendment No.2”) is entered into by and between the following Parties in Shanghai Municipality, China on this 5th day of November 2007:

 

11.                               Shanghai Traditional Chinese Medicine Co., Ltd. (“Party A”)
 Registered address: 239 Hankou Road, Shanghai Municipality, China
 Legal Representative: Chen Bao Hua
 Title: Chairman
 Nationality: Chinese

 

12.                               Shanghai Hutchison Chinese Medicine (HK) Investment Limited (“Party B”)
 Registered address: 22nd Floor, Hutchison House, 10 Harcourt Road, Central, Hong Kong
 Authorized legal representative: Mr. Simon To Chi Keung
 Title: Board Director
 Nationality: British

 

The above parties hereinafter are collectively referred to as the “Parties” and individually referred to as a “Party”.

 

WHEREAS,

 

Hutchison Chinese Medicine (Shanghai) Investment Limited (“Original Party B”), one of the investing parties of Shanghai Hutchison Pharmaceuticals Limited (the “JVC”), desires to transfer all of its 50% equity interest in the JVC to Shanghai Hutchison Chinese Medicine (HK) Investment Limited,  which makes it necessary to amend the Joint Venture Contract (the “JV Contract”) dated January 6, 2001 entered into by the Original Party B and Party A, as amended on July 12, 2001 (the “First Amendment”).

 

NOW THEREFORE, after negotiations, Party A and Party B agrees to amend the JV Contract as amended by the First Amendment as follows:

 

	
13.
    	
Original:
    	
THIS EQUITY JOINT VENURE CONTRACT    (the “Contract”) is jointly signed in Shanghai Municipality, People’s   Republic of China on this sixth day of January 2001 by and between:
    
	
 
    	
 
    	
 
    
	
 
    	
 
    	
Party A:                           Shanghai Traditional   Chinese Medicine Co., Ltd.

 

Party B:                           Hutchison Chinese   Medicine (Shanghai) Investment Limited
    
	
 
    	
 
    	
 
    
	
Amendment:
    	
THIS EQUITY JOINT CONTRACT (the “Contract”) is jointly signed in   Shanghai Municipality, People’s Republic of China on this sixth day of   January 2001 by and between Shanghai Traditional Chinese Medicine   Co., Ltd. and Hutchison Chinese Medicine (Shanghai) Investment Limited,   amended for the first time on the 12th day   of July 2001 by and between Shanghai Traditional Chinese Medicine   Co., Ltd. and Hutchison Chinese Medicine (Shanghai) Investment Limited,   and amended for the second time on November 5, 2007 by and between   Shanghai Traditional Chinese Medicine Co., Ltd. and Shanghai Hutchison   Chinese Medicine 
    

 

2

 

	
 
    	
 
    	
(HK) Investment Limited.
    
	
 
    	
 
    	
 
    
	
14.
    	
Original:
    	
The Parties of this Contract are:

Party A:     Shanghai   Traditional Chinese Medicine Co., Ltd., a corporate legal person   established and existing pursuant to the laws of the PRC and registered with   the Shanghai Municipal Administration for Industry and Commerce, China, with   its legal address at 239 Hankou Road, Shanghai Municipality, China; Fax   number: (86-21) 6350 2061.

 

The authorized legal representative for   this Contract:

 

Name: Mr. Xu Qinfa

 

Title: Chairman

 

Nationality: Chinese

 

Party B:      Hutchison   Chinese Medicine (Shanghai) Investment Limited, a limited liability company   established and existing pursuant to the laws of British Virgin Islands, with   its registered address at P.O. Box 957, Offshore Incorporation Centre,   Road Town, Tortola, British Virgin Islands and its correspondence address at   Room 2018, 22nd Floor, Hutchison House, 10 Harcourt Road, Central, Hong Kong;   Fax number: (852)28100772

 

The authorized legal representative for   this Contract:

 

Name: Mr. Simon To Chi Keung

 

Title: Board Director
    
	
 
    	
 
    	
 
    
	
Amendment:
    	
The Parties of this Contract are:
    
	
 
    	
 
    
	
 
    	
Party A:
    	
Shanghai Traditional Chinese Medicine Co., Ltd., a corporate   legal person established and existing pursuant to the laws of the PRC and   registered with the Shanghai Municipal Administration for Industry and   Commerce, China, with its legal address at 239 Hankou Road, Shanghai   Municipality, China; Fax number: (86-21) 6350 2061.

 

The authorized legal representative for   this Contract:

 

Name: Mr. Xu Qinfa

 

Title: Chairman

 

Nationality: Chinese
    
					

 

3

 

	
 
    	
Party B:
    	
Shanghai Hutchison Chinese Medicine (HK) Investment Limited, a limited   liability company established and existing pursuant to the laws of Hong Kong,   with its registered address at 22nd Floor, Hutchison House, 10 Harcourt Road,   Central, Hong Kong; Fax number: (852) 2810 0772

 

The authorized legal representative for   this Contract:

 

Name: Mr. Simon To Chi Keung

 

Title: Board Director

 

Nationality: British
    

 

15.                               Party B undertakes that after the legal formalities for the transfer of 50% of the equity interest of the JVC to Party B have been completed, Party B shall assume all of the Original Party B’s obligations and liabilities under the JV Contract and the Articles of the Association of the JVC.

 

16.                               The validity, interpretation and performance of this Amendment No.2 shall be governed by the laws of the People’s Republic of China.

 

17.                               This Amendment No.2 is an integral part of the JVC Contract.  Except as otherwise amended and supplemented herein, the JV Contract shall remain in full force and effect.  The JV Contract shall be construed and interpreted as if the provisions provided herein were included in the JV Contract.

 

18.                               This agreement shall come into effect upon the approval of the original examination and approval authority.

 

 

	
Shanghai Traditional Chinese Medicine Co., Ltd.
    
	
 
    
	
/s/ Xu Qinfa
    	
 
    
	
Legal Representative or Authorized Representative (signature and   company seal)
    
	
 
    
	
 
    
	
Shanghai Hutchison Chinese Medicine (HK) Investment Limited
    
	
 
    
	
/s/ Simon To Chi Keung
    	
 
    
	
Legal Representative or Authorized Representative (signature and   company seal)
    
	
 
    
	
 
    
	
November 5, 2007
    

 

4Exhibit 10.17

 

English Translation

 

THIRD AMENDMENT TO JOINT VENTURE CONTRACT

 

THIS THIRD AMENDMENT TO JOINT VENTURE CONTRACT (the “Amendment No.3”) is entered into by and between the following Parties in Shanghai Municipality, China as of June 19, 2012:

 

19.                               Shanghai Traditional Chinese Medicine Co., Ltd., a corporate legal person registered in the Shanghai Municipality, China, with its registered address at 239 Hankou Road, Shanghai Municipality, China (“Party A”); and

 

20.                               Shanghai Hutchison Chinese Medicine (HK) Investment Limited, a limited company registered in Hong Kong, with its registered address at 22nd Floor, Hutchison House, 10 Harcourt Road, Central, Hong Kong (“Party B”).

 

WHEREAS,

 

21.                               Party A and Hutchison Chinese Medicine (Shanghai) Investment Limited  (the “Original Party B”) entered into the Joint Venture Contract (the “JV Contract”) dated January 1, 2001 relating to the formation of Shanghai Hutchison Pharmaceuticals Limited (the “JVC”);

 

22.                               The JVC obtained the Approval Certificate of Foreign-invested Enterprise on March 19, 2001 and the Business Licence for Corporate Legal Person on April 30, 2001;

 

23.                               Party A and the Original Party B entered into the First Amendment to Joint Venture Contract on July 12, 2001 (the Amendment No.1) ;

 

24.                               Party A and Party B entered into the Second Amendment to Joint Venture Contract on November 5, 2007 ( together with the JV Contract and the Amendment No.1  hereinafter collectively referred to as the “Original Contract”); and

 

25.                               Party A and Party B desire to amend the Original Contract to reflect the following: a) Party A has changed its legal representative, and b) the Company Law of the People’s Republic of China requires equity joint venture enterprises set up Supervisors.

 

NOW THEREFOR, the Parties agree to the following terms and conditions:

 

26.                               The Parties agree that the first page of the Original Contract is hereby amended to read as follows:

 

THIS EQUITY JOINT CONTRACT (“Contract”) is jointly signed in Shanghai Municipality, People’s Republic of China on this sixth day of January 2001 by and between Shanghai Traditional Chinese Medicine Co., Ltd. and Hutchison Chinese Medicine (Shanghai) Investment Limited, amended for the first time on the 12th day of July 2001 by and between Shanghai Traditional Chinese Medicine Co., Ltd. and Hutchison Chinese Medicine (Shanghai) Investment Limited, amended for the second time on November 5, 2007 by and between Shanghai Traditional Chinese Medicine Co.,

 

 

Ltd. and Shanghai Hutchison Chinese Medicine (HK) Investment Limited, and amended for the third time on June 19, 2012.

 

The Parties of this Contract are:

 

Party A:                                                   Shanghai Traditional Chinese Medicine Co., Ltd., a corporate legal person established and existing pursuant to the laws of the PRC and registered with the Shanghai Municipal Administration for Industry and Commerce, China, with its legal address at 239 Hankou Road, Shanghai Municipality, China

 

the authorized legal representative for this Contract:

 

Name: Mr. Li Yongzhong

 

Title: Chairman

 

Nationality: Chinese

 

Party B:                                                   Shanghai Hutchison Chinese Medicine (HK) Investment Limited, a limited liability company established and existing pursuant to the laws of Hong Kong, with its legal address at 22nd Floor, Hutchison House, 10 Harcourt Road, Central, Hong Kong

 

the authorized legal representative for this Contract:

 

Name: Mr. Simon To Chi Keung

 

Title: Board Director

 

Nationality: British

 

27.                               The Parties agree to add Chapter 8A Supervisors to the Original Contract after Chapter 8 Board of Directors as follows:

 

Chapter 8A Supervisors

 

8A.01               The JVC shall have two Supervisors, and each Party shall appoint one Supervisor.  The Supervisors shall perform their duties and exercise their powers independently. The Supervisors shall have a term of three (3) years. Upon the expiration of term of a Supervisor, if the Party who appointed such Supervisor fails to send a notice to the JVC requiring the removal of the Supervisor, the Supervisor shall be deemed to have been reappointed by such Party. Both Parties may decide to replace or remove the Supervisor appointed by such Party at any time

 

8A.02               The Supervisors shall perform the following duties:

 

i.                                          to examine the JVC’s financial affairs;

 

2

 

ii.                                       to monitor the acts of the Directors and senior personnel when carrying out their duties in relation to the JVC, and to make proposals to remove from their positions any Directors or any senior personnel who violates any law, administrative regulation or the Articles of Association of the JVC;

 

iii.                                    to require the Directors or senior personnel to rectify their conduct when any of their actions damage the interests of the JVC;

 

iv.                                   to propose to convene interim Board meetings;

 

v.                                      to put forward proposals at Board meetings;

 

vi.                                   to bring lawsuits against Directors or senior personnel in accordance with Section 152 of the Company Law; and

 

vii.                                other functions and duties that should be performed by the Supervisors.

 

8A.03               Any of the Supervisors may investigate into abnormalities that he/she finds in the JVC’s operation, and may engage advisers such as an accounting firm to assist with the investigation as and when needed, the cost of which shall be assumed by the JVC.

 

8A.04               The JVC shall be responsible for all expenses necessary for such Supervisor to exercise his/her functions and duties.

 

28.                               The terms and conditions of the Original Contract, not amended by this Amendment No.3, shall remain in full force and effect. This Amendment No.3 is the integral part of the Original Contract.

 

29.                               The validity, interpretation, performance and settlement of disputes relating to this Amendment No.3 shall be governed by the laws of the People’s Republic of China.

 

30.                               The Amendment No.3 shall come into effect upon signature by the duly authorized representatives of the Parties. The Parties may enter into supplemental agreements for matters not covered herein.

 

31.                               There shall be six copies of the Amendment No.3, with each Party and the JVC holding one copy, and the remaining will be filed with the relevant governmental authorities for record.

 

32.                               This Amendment No.3 is signed by the authorized representatives of Party A and Party B as of the date stated on the first page.

 

3

 

Party A:  Shanghai Traditional Chinese Medicine Co., Ltd.

 

 

	
/s/ Xu Qinfa
    	
 
    
	
Authorized Representative Signature and Company Seal
    
	
 
    
	
 
    
	
Party B: Shanghai Hutchison Chinese Medicine (HK) Investment Limited
    
	
 
    
	
 
    
	
/s/ Simon To Chi Keung
    	
 
    
	
Authorized Representative Signature and Company Seal)
    

 

4

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