Document:

Orgenesis Inc.: Exhibit 10.2 - Filed by newsfilecorp.com

	ORGENESIS INC. 
	(the “Issuer”) 
	 
	PRIVATE PLACEMENT SUBSCRIPTION AGREEMENT 
	 
	(CONVERTIBLE NOTE) 
	 
	INSTRUCTIONS TO SUBSCRIBER 

1.          
You must complete all the information in the boxes on page 2 and sign where
indicated with an “X”. 

2.          
If you are a “U.S. Purchaser”, as defined in Exhibit A, you must complete and
sign Exhibit A “United States Accredited Investor Questionnaire”. 

3.          
If you are paying for your subscription with funds drawn from a U.S. bank or Non
U.S. source, you may pay by by wire transfer to the Issuer pursuant to the
wiring instructions set out in Exhibit B. 

ORGENESIS INC. 
PRIVATE
PLACEMENT SUBSCRIPTION AGREEMENT 

The undersigned (the “Subscriber”) hereby irrevocably
subscribes for and agrees to purchase from Orgenesis Inc. (the “Issuer”)
a 2% Unsecured Convertible Note of the Issuer (the “Note”) in the
principal amount set forth below. The form of the Note is attached to this
Subscription Agreement as Exhibit C. The Subscriber agrees to be bound by
the terms and conditions set forth in the attached “Terms and Conditions of
Subscription for Note”. 

	 	Subscriber Information 	 	 	Note to be Purchased 
	 	  	 	 	  
	 	  	 	 	Principal Amount of Note: $
250,000________
	 	  	 	 	  
	 	(Name of Subscriber) 	 	 	 
    
	 	  	 	 	  
	 	Account Reference (if applicable):
      ____________________	 	 	 
    
	 	  	 	 	Total
      Subscription Price: $250,000_________ 
	 	X 	 	 	(the
      “Subscription Amount”, plus wire fees if 
	 	(Signature of Subscriber – if the 	 	 	applicable) 
	 	Subscriber is an Individual) 	 	 	  
	 	  	 	 	  
	 	  	 	 	  
	 	X 	 	 	  
	 	(Signature of Authorized Signatory – if
      the 	 	 	Please complete if purchasing as agent or 
	 	Subscriber is not an Individual) 	 	 	trustee for a principal (beneficial purchaser) 
	 	  	 	 	(a
      “Disclosed Principal”) and not purchasing 
	 	 
    	 	 	as
      trustee or agent for accounts fully managed 
	 	(Name and Title of Authorized Signatory – if
	 	 	by
      it. 
	 	the Subscriber is not an Individual) 	 	 	 
    
	 	  	 	 	  
	 	(SSN or other Tax Identification Number of 	 	 	(Name
      of Disclosed Principal) 
	 	the Subscriber) 	 	 	 
    
	 	  	 	 	  
	 	  	 	 	(Address of Disclosed Principal) 
	 	  	 	 	  
	 	(Subscriber’s Address, including postal or zip
    	 	 	  
	 	code) 	 	 	(Account Reference, if applicable) 
	 	  	 	 	  
	 	(Telephone Number) 	 	 	  
	 	(Email Address) 	 	 	(SSN or
      other Tax Identification Number of 
	 	 
    	 	 	Disclosed Principal) 

2

	 	Register the Note as set forth below: 	 	 	Deliver the Note as set forth below: 
	 	  	 	 	 
	 	  	 	 	 
	 	(Name
      to Appear on Note Certificate) 	 	 	(Attention - Name) 
	 	  	 	 	 
	 	  	 	 	 
	 	(Account Reference, if applicable) 	 	 	(Account Reference, if applicable) 
	 	  	 	 	 
	 	  	 	 	 
	 	  	 	 	(Street
      Address, including postal or zip code – no 
	 	(Address, including postal or zip code) 	 	 	PO
      Boxes permitted) 
	 	  	 	 	 
	 	  	 	 	 
	 	  	 	 	 
	 	  	 	 	(Telephone Number) 
	 	  	 	 	 
	 	Number and kind of securities of the Issuer 	 	 	 
	 	already held, directly or indirectly, or over 	 	 	 
	 	which control or direction is exercised by, 	 	 	 
	 	the
      Subscriber, if any (i.e., shares, 	 	 	
	 	warrants, options): 	 	 	 
	 	 	 	 	 
	 	 	 	 	 
	 	 	 	 	 

3

ACCEPTANCE 

The Issuer hereby accepts the Subscription (as defined herein)
on the terms and conditions contained in this private placement subscription
agreement (this “Agreement”) as of the 21st day of November,
2018 (the “Closing Date”). 

ORGENESIS INC. 

Per:   /s/ Neil Reithinger

              
Authorized Signatory 

4 

TERMS AND CONDITIONS OF SUBSCRIPTION FOR NOTE

1.          
Subscription 

1.1         On the
basis of the representations and warranties, and subject to the terms and
conditions, set forth in this Agreement and in the form of Note attached as
Exhibit C to this Agreement, the Subscriber hereby irrevocably subscribes
for and agrees to purchase a Note in the principal amount as set forth on page 2
of this Agreement for the Subscription Amount shown on page 2 of this Agreement,
which is tendered herewith (such subscription and agreement to purchase being
the “Subscription”), and the Issuer agrees to sell the Note to the
Subscriber, effective upon the Issuer’s acceptance of this Agreement. 

1.2         The
principal amount of the Note will accrue interest at 2% per annum. The Note will
be an unsecured obligation of the Issuer. The Subscriber hereby confirms and
acknowledges that the Issuer may use the Subscription Amount, either in part or
in full, in any manner as the Issuer deems advisable including, without
limitation, to issue that certain convertible promissory note in the amount of
$1,000,000 to Immugenyx (or an affiliate thereof). Subject to Section 3 of the
Note, within two (2) years from the date hereof (the “Conversion
Period”), the Subscriber shall be entitled, at its option, to convert, at
any time and from time to time, until payment in full of the Note, all or any
portion of the outstanding principal amount of the Note, plus accrued and unpaid
interest thereon, into either of the following (as shall be determined by the
Subscriber in his discretion):

	 	1.2.1 	
      Units of the Issuer. The term “Units” shall mean
      one (1) share (each, a “Conversion Share”) of the Issuer’s common
      stock, par value $0.0001 per share (the “Common Stock”), and one
      warrant to purchase one share of Common Stock (the “Warrants”).
      Each Warrant shall entitle the holder to purchase one share of Common
      Stock (the “Warrant Shares”) at an exercise price of $7.00 per
      share (the “Exercise Price”), subject to adjustment, and shall be
      exercisable for a period of three years from the date hereof.

	 	 	 
	 	1.2.2 	
      shares of capital stock of Immugenyx at a price per share
      based on a pre-money valuation of Immugenyx of $12,000,000 (the
      “Immugenyx Securities”, and collectively with the Note, Conversion
      Shares, Warrant and Warrant Shares referred to herein as the
  “Securities”).

1.3         In the
event the Subscriber does not elect to convert the principal amount of the Note,
plus accrued and unpaid interest thereon, into Immugenyx Securities during the
Conversion Period, the Conversion Period shall be extended by an additional one
(1) year during which the Subscriber may convert the principal amount of the
Note, plus accrued and unpaid interest thereon, solely into Units. In no event
may the Subscriber convert such amounts into Immugenyx Securities after the
expiration of the Conversion Period. 

1.4         The
Subscriber acknowledges that the Note has been offered to the Subscriber as part
of an offering (the “Offering”) in which the Issuer intends to sell up to
an aggregate of $10,000,000 of principal amount of the Notes on the same terms
as set forth in this Agreement. 

1.5         All
dollar amounts referred to in this Agreement are in lawful money of the United
States of America, unless otherwise indicated. 

2.          
Payment 

2.1         Payment
of the Aggregate Subscription Price is required upon submission of the
subscription documents. 

5

2.2         The
Subscriber acknowledges and agrees that this Agreement, the Subscription Amount
and any other documents delivered in connection herewith will be held by or on
behalf of the Issuer. In the event that this Agreement is not accepted by the
Issuer for whatever reason, which the Issuer expressly reserves the right to do,
the Issuer will return the Subscription Amount (without interest thereon) to the
Subscriber at the address of the Subscriber as set forth on page 2 of this
Agreement, or as otherwise directed by the Subscriber. 

3.          
Documents Required from Subscriber 

3.1         The
Subscriber must complete, sign and return to the Issuer the following documents:

(a)           this Agreement;

(b)          
if the Subscriber is a U.S. Purchaser (as defined in Exhibit A), the
United States Accredited Investor Questionnaire (the “Questionnaire”)
attached as Exhibit A; 

(c)          
such other supporting documentation that the Issuer or the Issuer’s Counsel may
request to establish the Subscriber’s qualification as a qualified investor; and

(d)          
the Subscriber acknowledges and agrees that the Issuer will not consider the
Subscription for acceptance unless the Subscriber has provided all of such
documents to the Issuer. 

3.2         As
soon as practicable upon any request by the Issuer, the Subscriber will
complete, sign and return to the Issuer any additional documents,
questionnaires, notices and undertakings as may be required by any regulatory
authorities or applicable laws. 

3.3         The
Issuer and the Subscriber acknowledge and agree that the Issuer’s Counsel has
acted as counsel only to the Issuer and is not protecting the rights and
interests of the Subscriber. The Subscriber acknowledges and agrees that the
Issuer and the Issuer’s Counsel have given the Subscriber the opportunity to
seek, and are hereby recommending that the Subscriber obtain, independent legal
advice with respect to the subject matter of this Agreement and, further, the
Subscriber hereby represents and warrants to the Issuer and the Issuer’s Counsel
that the Subscriber has sought independent legal advice or waives such advice.

4.          
Conditions and Closing 

The Subscriber acknowledges that the Note will be available for
delivery within five (5) Business Days of the Issuer’s acceptance of the
subscription hereunder, provided that the Subscriber has satisfied the
requirements of Section 3 hereof and the Issuer has accepted this Agreement.

5.          
Acknowledgements and Agreements of the Subscriber 

The Subscriber acknowledges and agrees that: 

(a)          
none of the Securities have been or will be registered under the United States
Securities Act of 1933, as amended, (the “1933 Act”), or under any
securities or “blue sky” laws of any state of the United States, and, unless so
registered, may not be offered or sold in the United States or, directly or
indirectly, to any U.S. Person (as defined in Section 902 of Regulation S),
except in accordance with the provisions of Regulation S under the 1933 Act
(“Regulation S”), pursuant to an effective registration statement under
the 1933 Act, or pursuant to an exemption from, or in a transaction not subject
to, the registration requirements of the 1933 Act, and in each case
only in accordance with applicable securities laws; 

6

(b)          
  the Issuer has not undertaken, and will have no obligation, to register any of
the Securities under the 1933 Act or any other applicable securities laws;

(c)          
the Issuer will refuse to register the transfer of any of the Securities to a
U.S. Person not made pursuant to an effective registration statement under the
1933 Act or pursuant to an available exemption from the registration
requirements of the 1933 Act and in each case in accordance with applicable
laws; 

(d)          
the decision to execute this Agreement and to acquire the Securities has not
been based upon any oral or written representation as to fact or otherwise made
by or on behalf of the Issuer and such decision is based entirely upon a review
of any public information which has been filed by the Issuer with the United
States Securities and Exchange Commission (the “SEC”) (collectively, the
“Public Record”); 

(e)          
the Issuer and others will rely upon the truth and accuracy of the
acknowledgements, representations, warranties, covenants and agreements of the
Subscriber contained in this Agreement and the Questionnaire, as applicable, and
agrees that if any of such acknowledgements, representations and agreements are
no longer accurate or have been breached, the Subscriber will promptly notify
the Issuer; 

(f)          
there are risks associated with the purchase of the Securities, as more fully
described in the Public Record; 

(g)          
the Subscriber and the Subscriber’s advisor(s) have had a reasonable opportunity
to ask questions of, and receive answers from, the Issuer in connection with the
distribution of the Securities hereunder, and to obtain additional information,
to the extent possessed or obtainable without unreasonable effort or expense,
necessary to verify the accuracy of the information about the Issuer; 

(h)          
a portion of the Offering may be sold pursuant to an agreement between the
Issuer and one or more agents registered in accordance with applicable
securities laws, in which case the Issuer will pay a fee and/or compensation
security on terms as set out in such agreement; 

(i)          
finder’s fees or broker’s commissions may be payable by the Issuer to finders
who introduce subscribers to the Issuer; 

(j)          
the books and records of the Issuer were available upon reasonable notice for
inspection, subject to certain confidentiality restrictions, by the Subscriber
during reasonable business hours at its principal place of business, and all
documents, records and books in connection with the distribution of the
Securities hereunder have been made available for inspection by the Subscriber,
its legal counsel and/or its advisor(s); 

(k)          
all of the information which the Subscriber has provided to the Issuer is
correct and complete and if there should be any change in such information prior
to the Closing, the Subscriber will immediately notify the Issuer, in writing,
of the details of any such change; 

(l)          
the Issuer is entitled to rely on the representations and warranties of the
Subscriber contained in this Agreement and the Questionnaire, as applicable, and
the Subscriber will hold harmless the Issuer from any loss or damage it or they
may suffer as a result of the Subscriber’s failure to correctly complete this
Agreement or the Questionnaire, as applicable; 

7

(m)          
any resale of the Securities by the Subscriber will be subject to resale
restrictions contained in the securities laws applicable to the Issuer, the
Subscriber and any proposed transferee, including resale restrictions imposed
under United States securities laws and additional restrictions on the
Subscriber’s ability to resell any of the Securities in any other jurisdiction
under applicable securities laws; 

(n)          
it is the responsibility of the Subscriber to find out what any applicable
resale restrictions are and to comply with such restrictions before selling any
of the Securities; 

(o)          
the Subscriber has been advised to consult the Subscriber’s own legal, tax and
other advisors with respect to the merits and risks of an investment in the
Securities and with respect to applicable resale restrictions, and it is solely
responsible (and the Issuer is not in any way responsible) for compliance with:

(i)           any applicable
laws of the jurisdiction in which the Subscriber is resident in connection with
the distribution of the Securities hereunder, and 

(ii)          applicable
resale restrictions;

(p)         there may be material
tax consequences to the Subscriber of an acquisition or disposition of the
Securities and the Issuer gives no opinion and makes no representation to the
Subscriber with respect to the tax consequences to the Subscriber under federal,
state, provincial, local or foreign tax laws that may apply to the Subscriber’s
acquisition or disposition of the Securities; 

(q)          the Issuer has advised
the Subscriber that the Issuer is relying on an exemption from the requirements
to provide the Subscriber with a prospectus and to offer or sell the Securities
through a person registered to sell securities under applicable securities laws,
and, as a consequence of acquiring the Securities pursuant to such exemption,
certain protections, rights and remedies provided by applicable securities laws,
including statutory rights of rescission or damages, may not be available to the
Subscriber; 

(r)           no documents in
connection with the issuance of the Securities have been reviewed by the SEC or
any other securities regulators; 

(s)           neither the SEC
nor any other securities commission or similar regulatory authority has reviewed
or passed on the merits of any of the Securities; 

(t)           there is no
government or other insurance covering any of the Securities; 

(u)          hedging
transactions involving the Securities may not be conducted unless such
transactions are in compliance with the provisions of the 1933 Act and in each
case only in accordance with applicable securities laws; and 

(v)          this Agreement is
not enforceable by the Subscriber unless it has been accepted by the Issuer and
the Issuer reserves the right to reject this Subscription for any reason. 

6.          
Representations and Warranties of the Subscriber 

The Subscriber hereby represents and warrants to the Issuer
(which representations and warranties will survive the Closing) that: 

8

(a)           Unless the
Subscriber has completed Exhibit A, the Subscriber is not a U.S.
Purchaser; (b) the Subscriber is resident in the jurisdiction set out on page 2
of this Agreement; (c) if the Subscriber is resident outside of the United
States: 

(i)           the Subscriber
is knowledgeable of, or has been independently advised as to, the applicable
securities laws having application in the jurisdiction in which the Subscriber
is resident (the “International Jurisdiction”) which would apply to the
offer and sale of the Securities; 

(ii)          the Subscriber
is purchasing the Securities pursuant to exemptions from prospectus or
equivalent requirements under applicable laws of the International Jurisdiction
or, if such is not applicable, the Subscriber is permitted to purchase the
Securities under applicable securities laws of the International Jurisdiction
without the need to rely on any exemptions; 

(iii)          the applicable
laws and regulations of the International Jurisdiction do not and will not
require the Issuer to make any filings or seek any approvals of any kind from
any securities regulator of any kind in the International Jurisdiction in
connection with the offer, issue, sale or resale of any of the Securities; 

(iv)          the purchase of
the Securities by the Subscriber does not trigger: 

	 	A. 	
      any obligation to prepare and file a prospectus or
      similar document, or any other report with respect to such purchase in the
      International Jurisdiction, or

	 	 	 
	 	B. 	
      any continuous disclosure reporting obligation of the
      Issuer in the International Jurisdiction, and

(v)           the Subscriber
will, if requested by the Issuer, deliver to the Issuer a certificate or opinion
of local counsel from the International Jurisdiction which will confirm the
matters referred to in subparagraphs (ii), (iii) and (iv) above to the
satisfaction of the Issuer, acting reasonably; 

(d)          
the Subscriber: (i) has adequate net worth and means of providing for its
current financial needs and possible personal contingences, (ii) has no need for
liquidity in this investment, (iii) has such knowledge and experience in
business matters as to be capable of evaluating the merits and risks of its
prospective investment in the Securities, (iv) is able to bear the economic
risks of an investment in the Securities for an indefinite period of time, and
(v) can afford the complete loss of the Subscription Amount; 

(e)          
the Subscriber has the legal capacity and competence to enter into and execute
this Agreement and to take all actions required pursuant hereto and, if the
Subscriber is a corporate entity, it is duly incorporated and validly subsisting
under the laws of its jurisdiction of incorporation and all necessary approvals
by its directors, shareholders and others have been obtained to authorize
execution and performance of this Agreement on behalf of the Subscriber; 

(f)          
the entering into of this Agreement and the transactions contemplated hereby do
not and will not result in the violation of any of the terms and provisions of
any law applicable to, and, if applicable, any of the constating documents of,
the Subscriber or of any agreement, written or oral, to which the Subscriber may
be a party or by which the Subscriber is or may be bound; 

9

(g)          
the Subscriber has duly executed and delivered this Agreement and it constitutes
a valid and binding agreement of the Subscriber enforceable against the
Subscriber; 

(h)           the Subscriber
has received and carefully read this Agreement; 

(i)           
the Subscriber is aware that an investment in the Issuer is speculative and
involves certain risks, including those risks disclosed in the Public Record and
the possible loss of the entire Subscription Amount; 

(j)           
the Subscriber has made an independent examination and investigation of an
investment in the Securities and the Issuer and agrees that the Issuer will not
be responsible in any way for the Subscriber’s decision to invest in the
Securities and the Issuer; 

(k)          
the Subscriber is not an underwriter of, or dealer in, any of the Securities,
nor is the Subscriber participating, pursuant to a contractual agreement or
otherwise, in the distribution of the Securities; 

(l)           
the Subscriber is purchasing the Securities for its own account for investment
purposes only and not for the account of any other person and not for
distribution, assignment or resale to others, and no other person has a direct
or indirect beneficial interest in such Securities, and the Subscriber has not
subdivided its interest in any of the Securities with any other person; 

(m)          the
Subscriber is not aware of any advertisement of any of the Securities and is not
acquiring the Securities as a result of any form of general solicitation or
general advertising, including advertisements, articles, notices or other
communications published in any newspaper, magazine or similar media, or
broadcast over radio or television, or any seminar or meeting whose attendees
have been invited by general solicitation or general advertising;

(n)          
the Subscriber has not acquired the Securities as a result of, and will not
itself engage in, any “directed selling efforts” (as defined in Regulation S) in
the United States in respect of any of the Securities which would include any
activities undertaken for the purpose of, or that could reasonably be expected
to have the effect of, conditioning the market in the United States for the
resale of any of the Securities, provided, however, that the Subscriber may sell
or otherwise dispose of any of the Securities pursuant to registration of any of
the Securities pursuant to the 1933 Act and any applicable securities laws or
under an exemption from such registration requirements; and 

(o)           no person has
made to the Subscriber any written or oral representations: 

(i)           that any person
will resell or repurchase any of the Securities, 

(ii)          that any person
will refund the purchase price of any of the Securities, or 

(iii)         as to the future
price or value of any of the Securities. 

In this Agreement, the term “U.S. Person” will have the
meaning ascribed thereto in Regulation S, and for the purpose of this Agreement
includes, but is not limited to: (a) any person in the United States; (b) any
natural person resident in the United States; (c) any partnership or corporation
organized or incorporated under the laws of the United States; (d) any
partnership or corporation organized outside the United States by a U.S. Person
principally for the purpose of investing in securities not registered under the
1933 Act, unless it is organized or incorporated, and owned, by accredited
investors who are not natural persons, estates or trusts; or (e) any estate or trust
of which any executor or administrator or trustee is a U.S. Person. 

10

(p)          
  The Subscriber should check the Office of Foreign Assets Control (“OFAC”)
    website at <http://www.treas.gov/ofac> before making the following
representations.

(i)           The Subscriber
represents that the amounts invested by it in the Issuer in the offering
were not and are not directly or indirectly derived from activities that
contravene federal, state or international laws and regulations, including
anti-money laundering laws and regulations. Federal regulations and Executive
Orders administered by OFAC prohibit, among other things, the engagement in
transactions with, and the provision of services to, certain foreign countries,
territories, entities and individuals. The lists of OFAC prohibited countries,
territories, persons and entities can be found on the OFAC website at<
http://www.treas.gov/ofac. In addition, the programs administered by OFAC (the
“OFAC Programs”) prohibit dealing with individuals1 or entities in
certain countries regardless of whether such individuals or entities appear on
the OFAC lists; 

(ii)          To the best of
the Subscriber’s knowledge, none of: (1) the Subscriber; (2) any person
controlling or controlled by the Subscriber; (3) if the Subscriber is a
privately-held entity, any person having a beneficial interest in the
Subscriber; or (4) any person for whom the Subscriber is acting as agent or
nominee in connection with this investment is a country, territory, individual
or entity named on an OFAC list, or a person or entity prohibited under the OFAC
Programs. You are advised that the Issuer may not accept any amounts from a
prospective investor if such prospective investor cannot make the representation
set forth in the preceding paragraph. The Subscriber agrees to promptly notify
the Issuer should the Subscriber become aware of any change in the information
set forth in these representations. The Subscriber understands and acknowledges
that, by law, the Issuer may be obligated to “freeze the account” of the
Subscriber, either by prohibiting additional subscriptions from the Subscriber,
declining any redemption requests and/or segregating the assets in the account
in compliance with governmental regulations. These individuals include specially
designated nationals, specially designated narcotics traffickers and other
parties subject to OFAC sanctions and embargo programs; 

(iii)          To the best of
the Subscriber’s knowledge, none of: (1) the Subscriber; (2) any person
controlling or controlled by the Subscriber`; (3) if the Subscriber is a
privately-held entity, any person having a beneficial interest in the
Subscriber; or (4) any person for whom the Subscriber is acting as agent or
nominee in connection with this investment is a senior foreign political
figure,2 or any immediate family3 member or close
associate4 of a senior foreign political figure, as such terms are
defined in the footnotes below; and 

1 These individuals include specially designated
nationals, specially designated narcotics traffickers and other parties subject
to OFAC sanctions and embargo programs. 
2 A “senior foreign
political figure” is defined as a senior official in the executive, legislative,
administrative, military or judicial branches of a foreign government (whether
elected or not), a senior official of a major foreign political party, or a
senior executive of a foreign government-owned corporation. In addition, a
“senior foreign political figure” includes any corporation, business or other
entity that has been formed by, or for the benefit of, a senior foreign
political figure. 
3 “Immediate family” of a senior foreign
political figure typically includes the figure’s parents, siblings, spouse,
children and in-laws. 
4 A “close associate” of a senior foreign
political figure is a person who is widely and publicly known to maintain an
unusually close relationship with the senior foreign political figure and
includes a person who is in a position to conduct substantial domestic and
international financial transactions on behalf of the senior foreign political
figure. 

11

(iv)           If the
Subscriber is affiliated with a non-U.S. banking institution (a “Foreign Bank”),
or if the Subscriber receives deposits from, makes payments on behalf of, or
handles other financial transactions related to a Foreign Bank, the Subscriber
represents and warrants to the Issuer that: (1) the Foreign Bank has a fixed
address, other than solely an electronic address, in a country in which the
Foreign Bank is authorized to conduct banking activities; (2) the Foreign Bank
maintains operating records related to its banking activities; (3) the Foreign
Bank is subject to inspection by the banking authority that licensed the Foreign
Bank to conduct banking activities; and (4) the Foreign Bank does not provide
banking services to any other Foreign Bank that does not have a physical
presence in any country and that is not a regulated affiliate 

7.          
Representations and Warranties will be Relied Upon by the
Issuer 

The Subscriber acknowledges and agrees that the representations
and warranties contained in this Agreement and the Questionnaire, as applicable,
are made by it with the intention that such representations and warranties may
be relied upon by the Issuer and the Issuer’s Counsel in determining the
Subscriber’s eligibility to purchase the Securities under applicable laws, or,
if applicable, the eligibility of others on whose behalf the Subscriber is
contracting hereunder to purchase the Securities under applicable laws. The
Subscriber further agrees that, by accepting delivery of the certificate
representing the Note, it will be representing and warranting that the
representations and warranties contained herein are true and correct as at the
Closing Date with the same force and effect as if they had been made by the
Subscriber on the Closing Date and that they will survive the purchase by the
Subscriber of the Securities and will continue in full force and effect
notwithstanding any subsequent disposition by the Subscriber of such Securities.

8.          
Acknowledgement and Waiver 

The Subscriber has acknowledged that the decision to acquire
the Securities was solely made on the basis of the Public Record. The Subscriber
hereby waives, to the fullest extent permitted by law, any rights of withdrawal,
rescission or compensation for damages to which the Subscriber might be entitled
in connection with the distribution of any of the Securities. 

9.          
Legending of Securities 

The Subscriber hereby acknowledges that, upon the issuance
thereof, and until such time as the same is no longer required under applicable
securities laws, any certificates representing any of the Securities will bear a
legend in substantially the following form: 

“NONE OF THE SECURITIES REPRESENTED HEREBY HAVE BEEN REGISTERED
UNDER THE UNITED STATES SECURITIES ACT OF 1933, AS AMENDED (THE “1933 ACT”), OR
ANY U.S. STATE SECURITIES LAWS, AND, UNLESS SO REGISTERED, NONE MAY BE OFFERED
OR SOLD, DIRECTLY OR INDIRECTLY, IN THE UNITED STATES OR TO U.S. PERSONS EXCEPT
IN ACCORDANCE WITH THE PROVISIONS OF REGULATION S UNDER THE 1933 ACT, PURSUANT
TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE 1933 ACT, OR PURSUANT TO AN
EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION
REQUIREMENTS OF THE 1933 ACT AND IN EACH CASE ONLY IN ACCORDANCE WITH APPLICABLE
SECURITIES LAWS.” 

12

The Subscriber hereby acknowledges and agrees to the Issuer
making a notation on its records or giving instructions to the registrar and
transfer agent of the Issuer in order to implement the restrictions on transfer
set forth and described in this Agreement. 

10.          
Collection of Personal Information 

 10.1          
The Subscriber acknowledges and consents to the fact that the Issuer is
collecting the Subscriber’s personal information for the purpose of fulfilling
this Agreement and completing the Offering. The Subscriber acknowledges that its
personal information (and, if applicable, the personal information of those on
whose behalf the Subscriber is contracting hereunder) may be included in record
books in connection with the Offering and may be disclosed by the Issuer to: (a)
stock exchanges or securities regulatory authorities, (b) the Issuer's registrar
and transfer agent, (c) tax authorities, (d) authorities pursuant to the PATRIOT
Act (U.S.A.) and (e) any of the other parties involved in the Offering,
including the Issuer’s Counsel. By executing this Agreement, the Subscriber is
deemed to be consenting to the foregoing collection, use and disclosure of the
Subscriber's personal information (and, if applicable, the personal information
of those on whose behalf the Subscriber is contracting hereunder) for the
foregoing purposes and to the retention of such personal information for as long
as permitted or required by applicable laws. Notwithstanding that the Subscriber
may be purchasing the Note as agent on behalf of an undisclosed principal, the
Subscriber agrees to provide, on request, particulars as to the nature and
identity of such undisclosed principal, and any interest that such undisclosed
principal has in the Issuer, all as may be required by the Issuer in order to
comply with the foregoing. 

 10.2          
Furthermore, the Subscriber is hereby notified that the Issuer may deliver to
any government authority having jurisdiction over the Issuer, the Subscriber or
this Subscription, including the SEC and/or any state securities commissions,
certain personal information pertaining to the Subscriber, including the
Subscriber’s full name, residential address and telephone number, the number of
Shares or other securities of the Issuer owned by the Subscriber, the principal
amount of Note purchased by the Subscriber, the total Subscription Amount paid
for the Note and the date of distribution of the Note. 

11.          
Costs 

The Subscriber acknowledges and agrees that all costs and
expenses incurred by the Subscriber (including any fees and disbursements of any
special counsel retained by the Subscriber) relating to the purchase of the Note
will be borne by the Subscriber. 

12.          
Governing Law 

This Agreement is governed by the laws of the State of Nevada
(without reference to its rules governing the choice or conflict of laws). 

13.          
Survival 

This Agreement, including, without limitation, the
representations, warranties and covenants contained herein, will survive and
continue in full force and effect and be binding upon the Issuer and the
Subscriber, notwithstanding the completion of the purchase of the Securities by
the Subscriber. 

14.          
Assignment 

This Agreement is not transferable or assignable. 

13

15.          
Severability 

The invalidity or unenforceability of any particular provision
of this Agreement will not affect or limit the validity or enforceability of the
remaining provisions of this Agreement. 

16.          
Entire Agreement 

Except as expressly provided in this Agreement and in the
exhibits, agreements, instruments and other documents attached hereto or
contemplated or provided for herein, this Agreement contains the entire
agreement between the parties with respect to the sale of the Securities and
there are no other terms, conditions, representations or warranties, whether
expressed, implied, oral or written, by statute or common law, by the Issuer or
by anyone else. 

17.          
Notices 

All notices and other communications hereunder will be in
writing and will be deemed to have been duly given if hand delivered or
transmitted by any standard form of telecommunication, including facsimile,
electronic mail or other means of electronic communication capable of producing
a printed copy. Notices to the Subscriber will be directed to the address of the
Subscriber set forth on page 2 of this Agreement and notices to the Issuer will
be directed to it at the address of the Issuer set forth on page 3 of this
Agreement. 

18.          
Counterparts and Electronic Means 

This Agreement may be executed in any number of counterparts,
each of which, when so executed and delivered, will constitute an original and
all of which together will constitute one instrument. Delivery of an executed
copy of this Agreement by electronic facsimile transmission or other means of
electronic communication capable of producing a printed copy will be deemed to
be execution and delivery of this Agreement as of the Closing Date. 

19.          
Exhibits 

The exhibits attached hereto form part of this Agreement. 

20.          
Indemnity 

The Subscriber will indemnify and hold harmless the Issuer and,
where applicable, its directors, officers, employees, agents, advisors and
shareholders, from and against any and all loss, liability, claim, damage and
expense whatsoever (including, but not limited to, any and all fees, costs and
expenses whatsoever reasonably incurred in investigating, preparing or defending
against any claim, lawsuit, administrative proceeding or investigation whether
commenced or threatened) arising out of or based upon any representation or
warranty of the Subscriber contained in this Agreement, the Questionnaire or in
any document furnished by the Subscriber to the Issuer in connection herewith
being untrue in any material respect, or any breach or failure by the Subscriber
to comply with any covenant or agreement made by the Subscriber to the Issuer in
connection therewith. 

14

EXHIBIT A 

UNITED STATES ACCREDITED INVESTOR QUESTIONNAIRE

Capitalized terms used in this Questionnaire (this
“Questionnaire”) and not specifically defined have the meaning ascribed
to them in the Private Placement Subscription Agreement (the “Agreement”)
between the Subscriber and the Issuer to which this Exhibit A is attached. 

This Questionnaire applies only to persons that are U.S.
Purchasers. A “U.S. Purchaser” is: (a) any U.S. Person, (b) any person
purchasing the Note on behalf of any U.S. Person, (c) any person that receives
or received an offer of the Note while in the United States, or (d) any person
that is in the United States at the time the Subscriber’s buy order was made or
this Agreement was executed or delivered. 

The Subscriber understands and agrees that none of the
Securities have been or will be registered under the 1933 Act, or applicable
state, provincial or foreign securities laws, and the Securities are being
offered and sold to the Subscriber in reliance upon the exemption provided in
Section 4(a)(2) of the 1933 Act and Rule 506 of Regulation D under the 1933 Act
for non-public offerings. The Securities are being offered and sold within the
United States only to “accredited investors” as defined in Rule 501(a) of
Regulation D. The Securities offered hereby are not transferable except in
accordance with the restrictions described herein and the Agreement. 

The Subscriber represents, warrants, covenants and certifies
(which representations, warranties, covenants and certifications will survive
the Closing) to the Issuer (and acknowledges that the Issuer is relying thereon)
that: 

1.          
it has such knowledge and experience in financial and business matters as to be
capable of evaluating the merits and risks of an investment in the Securities
and it is able to bear the economic risk of loss of its entire investment; 

2.          
the Issuer has provided to it the opportunity to ask questions and receive
answers concerning the terms and conditions of the Offering and it has had
access to such information concerning the Issuer as it has considered necessary
or appropriate in connection with its investment decision to acquire the
Securities; 

3.          
it is acquiring the Securities for its own account, for investment purposes only
and not with a view to any resale, distribution or other disposition of the
Securities in violation of the United States securities laws; 

4.          
it (i) has adequate net worth and means of providing for its current financial
needs and possible personal contingencies, (ii) has no need for liquidity in
this investment, and (iii) is able to bear the economic risks of an investment
in the Securities for an indefinite period of time; 

5.          
if the Subscriber is an individual (that is, a natural person and not a
corporation, partnership, trust or other entity), then it satisfies one or more
of the categories indicated below (please place an “X” on the appropriate
lines): 

	 	_____________	
      a natural person whose individual net worth, or joint net
      worth with that person’s spouse, exceeds US$1,000,000. For purposes of
      this category, "net worth" means the excess of total assets at fair market
      value (including personal and real property, but excluding the estimated
      fair market value of a person's primary home) over total liabilities.
      Total liabilities excludes any mortgage on the primary home in an amount of up to the home's
estimated fair market value as long as the mortgage was incurred more than 60
days before the Securities are acquired, but includes (i) any mortgage amount in
excess of the home's fair market value and (ii) any mortgage amount that was
borrowed during the 60-day period before the date of the acquisition of
Securities for the purpose of investing in the Securities; 

15

		_____________	
      a natural person who had an individual income in excess
      of US$200,000 in each of the two most recent years, or joint income with
      their spouse in excess of US$300,000 in each of those years and has a
      reasonable expectation of reaching the same income level in the current
      year, or 

	 	 	  
	 	_____________	a director or executive officer of the Issuer.
    

6.          
if the Subscriber is a corporation, partnership, trust or other entity), then it
satisfies one or more of the categories indicated below (please place an “X” on
the appropriate lines): 

	 	_____________	
      an organization described in Section 501(c)(3) of the
      United States Internal Revenue Code, a corporation, a Massachusetts or
      similar business trust or partnership, not formed for the specific purpose
      of acquiring the Securities, with total assets in excess of US$5,000,000;
      

	 	 	
      

		_____________	
      a “bank” as defined under Section (3)(a)(2) of the 1933
      Act or savings and loan association or other institution as defined in
      Section 3(a)(5)(A) of the 1933 Act acting in its individual or fiduciary
      capacity; a broker dealer registered pursuant to Section 15 of the
      Securities Exchange Act of 1934 (United States); an insurance
      company as defined in Section 2(13) of the 1933 Act; an investment company
      registered under the Investment Company Act of 1940 (United
      States) or a business development company as defined in Section 2(a)(48)
      of such Act; a Small Business Investment Company licensed by the U.S.
      Small Business Administration under Section 301(c) or (d) of the Small
      Business Investment Act of 1958 (United States); a plan with total
      assets in excess of US$5,000,000 established and maintained by a state, a
      political subdivision thereof, or an agency or instrumentality of a state
      or a political subdivision thereof, for the benefit of its employees; an
      employee benefit plan within the meaning of the Employee Retirement
      Income Security Act of 1974 (United States) whose investment decisions
      are made by a plan fiduciary, as defined in Section 3(21) of such Act,
      which is either a bank, savings and loan association, insurance company or
      registered investment adviser, or if the employee benefit plan has total
      assets in excess of US$5,000,000, or, if a self- directed plan, whose
      investment decisions are made solely by persons that are accredited
      investors; 

	 	 	
      

		_____________	
      a private business development company as defined in
      Section 202(a)(22) of the Investment Advisers Act of 1940 (United
      States); 

	 	 	
      

		_____________	
      a trust with total assets in excess of US$5,000,000, not
      formed for the specific purpose of acquiring the Securities, whose
      purchase is directed by a sophisticated person as described in Rule
      506(b)(2)(ii) under the 1933 Act, or 

16

	 	_____________	
      an entity in which all of the equity owners satisfy the
      requirements of one or more of the categories set forth in Section 6 of
      this Questionnaire. 

7.          
it has not purchased the Securities as a result of any form of general
solicitation or general advertising, including advertisements, articles, notices
or other communications published in any newspaper, magazine or similar media or
broadcast over radio, internet, television or other form of telecommunications,
or any seminar or meeting whose attendees have been invited by general
solicitation or general advertising; 

8.          
if the Subscriber decides to offer, sell or otherwise transfer any of the
Securities, it will not offer, sell or otherwise transfer any of such
Securities, directly or indirectly, unless: 

(a)           the sale is to
the Issuer; 

(b)          
the sale is made outside the United States in a transaction meeting the
requirements of Rule 904 and 905 of Regulation S under the 1933 Act and in
compliance with applicable local laws and regulations in which such sale is
made; 

(c)          
the sale is made pursuant to the exemption from the registration requirements
under the 1933 Act provided by Rule 144 thereunder and in accordance with any
applicable state securities or “blue sky” laws; 

(d)          
the Securities are sold in a transaction that does not require registration
under the 1933 Act or any applicable state laws and regulations governing the
offer and sale of securities; and 

(e)          
it has, prior to such sale pursuant to subsection (b), (c) or (d), furnished to
the Issuer an opinion of counsel of recognized standing reasonably satisfactory
to the Issuer, to such effect. 

9.           
it understands and agrees that there may be material tax consequences to the
Subscriber of an acquisition or disposition of the Securities. The Issuer gives
no opinion and makes no representation with respect to the tax consequences to
the Subscriber under United States, state, local or foreign tax law of the
Subscriber’s acquisition or disposition of the Securities; 

10.          it
consents to the Issuer making a notation on its records or giving instructions
to any transfer agent of the Issuer in order to implement the restrictions on
transfer set forth and described in this Questionnaire and the Agreement; 

11.          it
is resident in the United States of America, its territories and possessions or
any state of the United States or the District of Columbia (collectively the
“United States”), is a “U.S. Person” as such term is defined in
Regulation S or was in the United States at the time the Securities were offered
or the Agreement was executed; and 

12.          except
as contemplated in the Agreement, it understands that the Issuer has no
obligation to register any of the Securities or to take action so as to permit
sales pursuant to the 1933 Act (including Rule 144 thereunder). 

17

The Subscriber undertakes to notify the Issuer immediately of
any change in any representation, warranty or other information relating to the
Subscriber set forth herein which takes place prior to the closing time of the
purchase and sale of the Securities. 

Dated: ___________, 2018. 

 

	  X
	  Signature of individual (if Subscriber is an 
	  individual) 
	  
	  X 
	  Authorized signatory (if Subscriber is not an 
	  individual) 
	  
	  
	  Name of Subscriber (please print) 
	  
	  
	  Name of authorized signatory (please print)
  

18

	EXHIBIT B 
	INSTRUCTIONS FOR WIRING FUNDS 
	  
	  
	ORGENESIS INC. 
	20271 Goldenrod Lane 
	Germantown, MD 20876 
	  
	REMITTANCE INSTRUCTIONS 
	JP Morgan Chase Bank 
	  
	Account Name: 
	Orgenesis Inc. 
	  
	Account #: 
	000000949139307 
	  
	Wire Routing Numbers: 
	Domestic – 021000021 
	  
	International (also referred to as Swift Code) - CHASUS33
    
	  
	ACH Routing Numbers: 
	022300173 

19EX-4.7

 Exhibit 4.7 

EYEPOINT PHARMACEUTICALS, INC. 

and 
  

 
 as Trustee

 INDENTURE 

Dated as of
                    , 

							
	ARTICLE 1 DEFINITIONS AND INCORPORATION BY REFERENCE 	  	 	1	 
	 1.1
	 	 Definitions
	  	 	1	 
	 1.2
	 	 Other Definitions
	  	 	5	 
	 1.3
	 	 Incorporation by Reference of Trust Indenture Act
	  	 	5	 
	 1.4
	 	 Rules of Construction
	  	 	6	 
	ARTICLE 2 THE SECURITIES 	  	 	6	 
	 2.1
	 	 Issuable in Series
	  	 	6	 
	 2.2
	 	 Establishment of Terms of Series of Securities
	  	 	7	 
	 2.3
	 	 Execution and Authentication
	  	 	9	 
	 2.4
	 	 Registrar and Paying Agent
	  	 	10	 
	 2.5
	 	 Paying Agent to Hold Assets in Trust
	  	 	11	 
	 2.6
	 	 Securityholder Lists
	  	 	11	 
	 2.7
	 	 Transfer and Exchange
	  	 	11	 
	 2.8
	 	 Replacement Securities
	  	 	12	 
	 2.9
	 	 Outstanding Securities
	  	 	13	 
	 2.10
	 	 When Treasury Securities Disregarded; Determination Of Holders
Action
	  	 	13	 
	 2.11
	 	 Temporary Securities
	  	 	13	 
	 2.12
	 	 Cancellation
	  	 	14	 
	 2.13
	 	 Payment of Interest; Defaulted Interest; Computation of
Interest
	  	 	14	 
	 2.14
	 	 Cusip Number
	  	 	14	 
	 2.15
	 	 Provisions for Global Securities
	  	 	15	 
	 2.16
	 	 Persons Deemed Owners
	  	 	16	 
	ARTICLE 3 REDEMPTION 	  	 	16	 
	 3.1
	 	 Notices to Trustee
	  	 	16	 
	 3.2
	 	 Selection by Trustee of Securities to be Redeemed
	  	 	17	 
	 3.3
	 	 Notice of Redemption
	  	 	17	 
	 3.4
	 	 Effect of Notice of Redemption
	  	 	18	 
	 3.5
	 	 Deposit of Redemption Price
	  	 	18	 
	 3.6
	 	 Securities Redeemed in Part
	  	 	19	 
	ARTICLE 4 COVENANTS 	  	 	19	 
	 4.1
	 	 Payment of Securities
	  	 	19	 
	 4.2
	 	 SEC REPORTS
	  	 	19	 
	 4.3
	 	 Waiver of Stay, Extension or Usury Laws
	  	 	19	 
	 4.4
	 	 Compliance Certificate
	  	 	20	 
	 4.5
	 	 Corporate Existence
	  	 	20	 
	ARTICLE 5 SUCCESSOR CORPORATION 	  	 	20	 
	 5.1
	 	 Limitation on Consolidation, Merger and Sale of Assets
	  	 	20	 
	 5.2
	 	 Successor Person Substituted
	  	 	21	 
	ARTICLE 6 DEFAULTS AND REMEDIES 	  	 	21	 
	 6.1
	 	 Events of Default
	  	 	21	 
	 6.2
	 	 Acceleration
	  	 	23	 
	 6.3
	 	 Remedies
	  	 	23	 
	 6.4
	 	 Waiver of Past Defaults and Events of Default
	  	 	24	 
	 6.5
	 	 Control by Majority
	  	 	24	 
	 6.6
	 	 Limitation on Suits
	  	 	24	 
	 6.7
	 	 Rights of Holders to Receive Payment
	  	 	25	 

  
 i 

							
	 6.8
	 	 Collection Suit by Trustee
	  	 	25	 
	 6.9
	 	 Trustee May File Proofs of Claim
	  	 	25	 
	 6.10
	 	 Priorities
	  	 	26	 
	 6.11
	 	 Undertaking for Costs
	  	 	26	 
	ARTICLE 7 TRUSTEE 	  	 	26	 
	 7.1
	 	 Duties of Trustee
	  	 	26	 
	 7.2
	 	 Rights of Trustee
	  	 	27	 
	 7.3
	 	 Individual Rights Of Trustee
	  	 	28	 
	 7.4
	 	 Trustee’s Disclaimer
	  	 	29	 
	 7.5
	 	 Notice of Default
	  	 	29	 
	 7.6
	 	 Reports by Trustee to Holders
	  	 	29	 
	 7.7
	 	 Compensation and Indemnity
	  	 	29	 
	 7.8
	 	 Replacement of Trustee
	  	 	30	 
	 7.9
	 	 Successor Trustee by Consolidation, Merger or Conversion
	  	 	31	 
	 7.10
	 	 Eligibility; Disqualification
	  	 	31	 
	 7.11
	 	 Preferential Collection of Claims Against Company
	  	 	31	 
	 7.12
	 	 Paying Agents
	  	 	31	 
	ARTICLE 8 AMENDMENTS, SUPPLEMENTS AND WAIVERS 	  	 	32	 
	 8.1
	 	 Without Consent of Holders
	  	 	32	 
	 8.2
	 	 With Consent of Holders
	  	 	33	 
	 8.3
	 	 Compliance With Trust Indenture Act
	  	 	34	 
	 8.4
	 	 Revocation and Effect of Consents
	  	 	34	 
	 8.5
	 	 Notation On or Exchange of Securities
	  	 	35	 
	 8.6
	 	 Trustee To Sign Amendments, Etc
	  	 	35	 
	ARTICLE 9 DISCHARGE OF INDENTURE; DEFEASANCE 	  	 	35	 
	 9.1
	 	 Discharge of Indenture
	  	 	35	 
	 9.2
	 	 Legal Defeasance
	  	 	35	 
	 9.3
	 	 Covenant Defeasance
	  	 	36	 
	 9.4
	 	 Conditions to Legal Defeasance or Covenant Defeasance
	  	 	36	 
	 9.5
	 	 Deposited Money And U.S. And Foreign Government Obligations To Be Held In
 Trust; Other Miscellaneous Provisions
	  	 	38	 
	 9.6
	 	 Reinstatement
	  	 	38	 
	 9.7
	 	 Moneys Held by Paying Agent
	  	 	39	 
	 9.8
	 	 Moneys Held by Trustee
	  	 	39	 
	ARTICLE 10 MISCELLANEOUS 	  	 	39	 
	 10.1
	 	 Trust Indenture Act Controls
	  	 	39	 
	 10.2
	 	 Notices
	  	 	40	 
	 10.3
	 	 Communications by Holders With Other Holders
	  	 	41	 
	 10.4
	 	 Certificate and Opinion as to Conditions Precedent
	  	 	41	 
	 10.5
	 	 Statement Required in Certificate and Opinion
	  	 	41	 
	 10.6
	 	 Rules by Trustee and Agents
	  	 	42	 
	 10.7
	 	 Business Days; Legal Holidays; Place of Payment
	  	 	42	 
	 10.8
	 	 Governing Law
	  	 	42	 
	 10.9
	 	 No Adverse Interpretation of Other Agreements
	  	 	42	 
	 10.10
	 	 Successors
	  	 	42	 
	 10.11
	 	 Multiple Counterparts
	  	 	42	 

  
 ii 

							
	 10.12
	 	 Table of Contents, Headings, Etc
	  	 	43	 
	 10.13
	 	 Severability
	  	 	43	 
	 10.14
	 	 Securities in a Foreign Currency or in Euros
	  	 	43	 
	 10.15
	 	 Judgment Currency
	  	 	44	 
	 10.16
	 	 Force Majeure
	  	 	44	 
	 10.17
	 	 U.S.A. Patriot Act
	  	 	44	 
	ARTICLE 11 SINKING FUNDS 	  	 	45	 
	 11.1
	 	 Applicability of Article
	  	 	45	 
	 11.2
	 	 Satisfaction of Sinking Fund Payments with Securities
	  	 	45	 
	 11.3
	 	 Redemption of Securities for Sinking Fund
	  	 	45	 

  
 iii 

 INDENTURE, dated as of
                , by and between EyePoint Pharmaceuticals, Inc., a Delaware corporation, as Issuer (the “Company”), and
                , a                 , organized under the laws of
                , as Trustee (the “Trustee”). 

RECITALS OF THE COMPANY 

The Company has duly authorized the execution and delivery of this Indenture to provide for the issuance from time to time of its debentures,
notes or other evidences of indebtedness to be issued in one or more series (the “Securities”), as herein provided, up to such principal amount as may from time to time be authorized in or pursuant to one or more resolutions of the
Board of Directors or by supplemental indenture. 
 All things necessary to make this Indenture a valid agreement of the Company in
accordance with its terms have been done, and the execution and delivery thereof have been in all respects duly authorized by the parties hereto. 

NOW, THEREFORE, THIS INDENTURE WITNESSETH: For and in consideration of the premises and the purchase of the Securities by the Holders
thereof, it is mutually agreed, for the equal and proportionate benefit of all Holders of the Securities of a Series thereof, as follows: 

ARTICLE 1 

DEFINITIONS AND INCORPORATION BY REFERENCE 

1.1    Definitions. 

“Affiliate” of any specified Person means any other Person which, directly or indirectly through one or more intermediaries,
controls, or is controlled by or is under common control with, such specified Person. For the purposes of this definition, “control” (including, with correlative meanings, the terms “controlling,” “controlled by” and
“under common control with”), as used with respect to any Person, means the possession, directly or indirectly, of the power to direct or cause the direction of the management or policies of such Person, whether through the ownership of
voting securities, by agreement or otherwise. 
 “Agent” means any Registrar, Paying Agent,
co-registrar or agent for service of notices and demands. 
 “Board of Directors”
means the Board of Directors of the Company or any committee duly authorized to act therefor. 
 “Board Resolution” means a
copy of a resolution certified pursuant to an Officers’ Certificate to have been duly adopted by the Board of Directors of the Company and to be in full force and effect on the date of such certification which has been delivered to the Trustee.

 “Capital Stock” means, with respect to any Person, any and all shares or other equivalents (however designated) of
capital stock, partnership interests or any other participation, right or other interest in the nature of an equity interest in such Person or any option, warrant or other security convertible into any of the foregoing. 

  
 1 

 “Company” means the party named as such in the first paragraph of this
Indenture until a successor replaces such party pursuant to Article 5 of this Indenture, and thereafter means the successor and any other primary obligor on the Securities. 

“Company Order” means a written order signed in the name of the Company by two of the Company’s executive Officers, one
of whom must be its Chief Executive Officer or its Chief Financial Officer. 
 “Company Request” means any written request
signed in the name of the Company by its Chief Executive Officer, its President, any Vice President, its Chief Financial Officer or its Treasurer and attested to by its Secretary or any Assistant Secretary. 

“Corporate Trust Office” means the office of the Trustee at which at any particular time its corporate trust business shall
be principally administered. 
 “Default” means any event that is, or that with the passing of time or giving of notice or
both would be, an Event of Default. 
 “Depository” means, with respect to the Securities of any Series issuable or
issued in whole or in part in the form of one or more Global Securities, the Person designated as Depository for such Series by the Company, which Depository shall be a clearing agency registered under the Exchange Act, until a successor
Depository shall have become such pursuant to the applicable provisions of this Indenture, and thereafter “Depository” shall mean each Person who is then a Depository hereunder, and if at any time there is more than one such Person, such
Persons. 
 “Dollars” means the currency of the United States of America. 

“Euro” means the single currency of participating member states of the economic and monetary union as contemplated in the
Treaty on European Union. 
 “Exchange Act” means the Securities Exchange Act of 1934, as amended. 

“Foreign Currency” means any currency or currency unit issued by a government other than the government of the United States
of America. 
 “Foreign Government Obligations” means, with respect to Securities that are denominated in a Foreign
Currency, (i) direct obligations of the government that issued or caused to be issued such currency for the payment of which obligations its full faith and credit is pledged or (ii) obligations of a Person controlled or supervised by, or
acting as an agency or instrumentality of, such government, the timely payment of which is unconditionally guaranteed as a full faith and credit obligation by such government, which, in either case under clauses (i) and (ii), are not callable
or redeemable at the option of the issuer thereof. 

  
 2 

 “GAAP” means generally accepted accounting principles consistently applied
as in effect in the United States of America from time to time. 
 “Global Security” or “Global Securities” means
a Security or Securities, as the case may be, in the form established pursuant to Section 2.2, evidencing all or part of a Series of Securities issued to the Depository for such Series or its nominee, and
registered in the name of such Depository or nominee, and bearing the legend set forth in Section 2.15(c) (or such other legend(s) as may be applied to such Securities in accordance with
Section 2.2(24)). 
 “Holder” or “Securityholder” means the Person in whose name
a Security is registered on the Registrar’s books. 
 “Indebtedness” means (without duplication), with respect to any
Person, any indebtedness at any time outstanding, secured or unsecured, contingent or otherwise, which is for borrowed money (whether or not the recourse of the lender is to the whole of the assets of such Person or only to a portion thereof), or
evidenced by bonds, notes, debentures or similar instruments, or representing the balance deferred and unpaid of the purchase price of any property (excluding any balances that constitute accounts payable or trade payables, and other accrued
liabilities arising in the ordinary course of business), if and to the extent any of the foregoing indebtedness would appear as a liability upon a balance sheet of such Person prepared in accordance with GAAP. 

“Indenture” means this Indenture as amended, restated or supplemented from time to time. 

“Interest Payment Date” when used with respect to any Security, means the Stated Maturity of an installment of interest on
such Security. 
 “Lien” means, with respect to any property or assets of any Person, any mortgage or deed of trust,
pledge, hypothecation, assignment, deposit arrangement, security interest, lien, charge, easement, encumbrance, preference, priority or other security agreement or preferential arrangement of any kind or nature whatsoever on or with respect to such
property or assets (including, without limitation, any capitalized lease obligation, conditional sales or other title retention agreement having substantially the same economic effect as any of the foregoing). 

“Maturity” when used with respect to any Security, means the date on which the principal of such Security, or an installment
of principal, becomes due and payable as therein or herein provided, whether at the Stated Maturity or by declaration of acceleration, call for redemption, notice of option to elect payment or otherwise. 

“Officer” means the Chief Executive Officer, the President, any Vice President, the Chief Financial Officer, the Treasurer or
the Secretary of the Company, or any other officer designated by the Board of Directors, as the case may be. 
 “Officers’
Certificate” means, with respect to any Person, a certificate signed by the Chairman, Chief Executive Officer, President or any Senior or Executive Vice President and the Chief Financial Officer or any Treasurer of such Person, that shall
comply with applicable provisions of this Indenture. 

  
 3 

 “Opinion of Counsel” means a written opinion from legal counsel, which
counsel is reasonably acceptable to the Trustee. The counsel may be an employee of or counsel to the Company. 
 “Person”
means any individual, corporation, limited liability company, partnership, joint venture, association, joint-stock company, trust, unincorporated organization or government (including any agency or political subdivision thereof). 

“Redemption Date,” when used with respect to any Security to be redeemed, means the date fixed for such redemption pursuant
to this Indenture. 
 “Responsible Officer,” when used with respect to the Trustee, means any officer within the corporate
trust department or division of the Trustee (or any successor group of the Trustee) or any other officer of the Trustee customarily performing functions similar to those performed by any of the above designated officers, and also means, with respect
to a particular corporate trust matter, any other officer to whom such matter is referred because of his knowledge of and familiarity with the particular subject. 

“SEC” means the United States Securities and Exchange Commission as constituted from time to time, or any successor
performing substantially the same functions. 
 “Securities” means the securities that are issued under this Indenture, as
amended or supplemented from time to time pursuant to this Indenture. 
 “Securities Act” means the Securities Act of 1933,
as amended. 
 “Series” or “Series of Securities” means each series of debentures,
notes or other debt instruments of the Company created pursuant to Sections 2.1 and 2.2. 

“Significant Subsidiary” means (i) any direct or indirect Subsidiary of the Company that would be a “significant
subsidiary” as defined in Article 1, Rule 1-02 of Regulation S-X, promulgated pursuant to the Securities Act, as such regulation is in effect on the date
hereof, or (ii) any group of direct or indirect Subsidiaries of the Company that, taken together as a group, would be a “significant subsidiary” as defined in Article 1, Rule 1-02 of
Regulation S-X, promulgated pursuant to the Securities Act, as such regulation is in effect on the date hereof. 

“Stated Maturity” when used with respect to any Security or any installment of principal thereof or interest thereon, means
the date specified in such Security as the fixed date on which the principal of such Security, or such installment of principal or interest, is due and payable, and when used with respect to any other Indebtedness, means the date specified in the
instrument governing such Indebtedness as the fixed date on which the principal of such Indebtedness, or any installment of interest thereon, is due and payable. 

“Subsidiary” of any specified Person means any corporation, limited liability company, partnership, joint venture,
association or other business entity, whether now existing or hereafter organized or acquired, (i) in the case of a corporation, of which more than 50% of the total voting power of the Capital Stock entitled (without regard to the occurrence of
any contingency) to vote in the election of directors thereof is held, directly or indirectly, by such Person or any of 

  
 4 

 
its Subsidiaries; or (ii) in the case of a partnership, joint venture, association or other business entity, with respect to which such Person or any of its Subsidiaries has the power to
direct or cause the direction of the management and policies of such entity by contract or otherwise, or if in accordance with GAAP such entity is consolidated with such Person for financial statement purposes. 

“TIA” means the Trust Indenture Act of 1939 (15 U.S. Code Section 77aaa-77bbbb) as in effect on the date of this
Indenture (except as provided in Section 8.3). 
 “Trustee” means the party named as such in this
Indenture until a successor replaces it pursuant to this Indenture, and thereafter means the successor, and if at any time there is more than one such Person, “Trustee” as used with respect to the Securities of any Series shall mean
the Trustee with respect to Securities of that Series. 
 “U.S. Government Obligations” means direct non-callable obligations of, or non-callable obligations guaranteed by, the United States of America for the payment of which obligation or guarantee the full faith and credit
of the United States of America is pledged. 
 1.2    Other Definitions. 

The definitions of the following terms may be found in the sections indicated as follows: 

 

			
	 TERM
	  	DEFINED IN SECTION
	 “Bankruptcy Law”
	  	6.1
	 “Business Day”
	  	10.7
	 “Covenant Defeasance”
	  	9.3
	 “Custodian”
	  	6.1
	 “Event of Default”
	  	6.1
	 “Journal”
	  	10.14
	 “Judgment Currency”
	  	10.15
	 “Legal Defeasance
	  	9.2
	 “Legal Holiday”
	  	10.7
	 “Market Exchange Rate”
	  	10.14
	 “New York Paying Agent”
	  	2.4
	 “Paying Agent”
	  	2.4
	 “Place of Payment”
	  	10.7
	 “Registrar”
	  	2.4
	 “Required Currency”
	  	10.15
	 “Service Agent”
	  	2.4

 1.3    Incorporation by Reference of Trust Indenture
Act. 
 Whenever this Indenture refers to a provision of the TIA, the portion of such provision required to be incorporated herein in
order for this Indenture to be qualified under the TIA is incorporated by reference in and made a part of this Indenture. The following TIA terms used in this Indenture have the following meanings: 

“Commission” means the SEC. 

  
 5 

 “indenture securities” means the Securities. 

“indenture securityholder” means a Holder or Securityholder. 

“indenture to be qualified” means this Indenture. 

“indenture trustee” or “institutional trustee” means the Trustee. 

“obligor on the indenture securities” means the Company. 

All other terms used in this Indenture that are defined by the TIA, defined in the TIA by reference to another statute or defined by SEC
rule have the meanings therein assigned to them. 
 1.4    Rules of
Construction. 
 Unless the context otherwise requires: 

(1)    a term has the meaning assigned to it herein, whether defined expressly or by reference; 

(2)    an accounting term not otherwise defined has the meaning assigned to it in accordance with GAAP; 

(3)    “or” is not exclusive; 

(4)    words in the singular include the plural, and in the plural include the singular; 

(5)    words used herein implying any gender shall apply to each gender; and 

(6)    the words “herein”, “hereof” and “hereunder” and other words of similar import refer
to this Indenture as a whole and not to any particular Article, Section or other subdivision. 
 ARTICLE 2

 THE SECURITIES 
 
2.1    Issuable in Series. 
 The aggregate principal amount of Securities that may be authenticated and
delivered under this Indenture is $                . The Securities may be issued in one or more Series. All Securities of a Series shall be identical except as may
be set forth in a Board Resolution, a supplemental indenture or an Officers’ Certificate detailing the adoption of the terms thereof pursuant to the authority granted under a Board Resolution. In the case of Securities of a Series to be
issued from time to time, the Board Resolution, Officers’ Certificate or supplemental indenture may provide for the method by which specified terms (such as interest rate, Stated Maturity, record date or date from which interest shall accrue)
are to be determined. Securities may differ between Series in respect of any matters, PROVIDED, that all Series of Securities shall be equally and ratably entitled to the benefits of the Indenture. 

  
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 2.2    Establishment of Terms of
Series of Securities. 
 At or prior to the issuance of any Securities within a Series, the following shall be established (as to the
Series generally, in the case of Subsection 2.2(1) and either as to such Securities within the Series or as to the Series generally in the case of Subsections 2.2(2) through
2.2(24)) by a Board Resolution, a supplemental indenture or an Officers’ Certificate, in each case, pursuant to authority granted under a Board Resolution: 

(1)    the title of the Series (which shall distinguish the Securities of that particular Series from the
Securities of any other Series); 
 (2)    any limit upon the aggregate principal amount of the Securities of the
Series which may be authenticated and delivered under this Indenture (except for Securities authenticated and delivered upon registration of transfer of, or in exchange for, or in lieu of, other Securities of the Series pursuant to
Sections 2.7, 2.8, 2.11, 3.6 or 8.5); 
 (3)    the price or prices
(expressed as a percentage of the principal amount thereof) at which the Securities of the Series will be issued; 

(4)    the date or dates on which the principal of the Securities of the Series is payable; 

(5)    the rate or rates (which may be fixed or variable) per annum or, if applicable, the method used to determine such
rate or rates (including, but not limited to, any commodity, commodity index, stock exchange index or financial index) at which the Securities of the Series shall bear interest, if any, the date or dates from which such interest, if any, shall
accrue, the date or dates on which such interest, if any, shall commence and be payable and any regular record date for the interest payable on any Interest Payment Date; 

(6)    the place or places where the principal of, and interest and premium, if any, on, the Securities of the Series shall
be payable, or the method of such payment, if by wire transfer, mail or other means; 
 (7)    if applicable, the period
or periods within which, the price or prices at which and the terms and conditions upon which the Securities of the Series may be redeemed, in whole or in part, at the option of the Company; 

(8)    the obligation, if any, of the Company to redeem or purchase the Securities of the Series pursuant to any sinking
fund or analogous provisions or at the option of a Holder thereof, and the period or periods within which, the price or prices at which and the terms and conditions upon which Securities of the Series shall be redeemed or purchased, in whole or in
part, pursuant to such obligation; 

  
 7 

 (9)    the dates, if any, on which and the price or prices at which the
Securities of the Series will be repurchased by the Company at the option of the Holders thereof, and other detailed terms and provisions of such repurchase obligations; 

(10)    if other than denominations of $1,000 and any integral multiple thereof, the denominations in which the Securities
of the Series shall be issuable; 
 (11)    the forms of the Securities of the Series in bearer (if to be issued outside
of the United States of America) or fully registered form (and, if in fully registered form, whether the Securities will be issuable as Global Securities); 

(12)    if other than the principal amount thereof, the portion of the principal amount of the Securities of the
Series that shall be payable upon declaration of acceleration of the Maturity thereof pursuant to Section 6.2; 

(13)    the currency of denomination of the Securities of the Series, which may be Dollars or any Foreign Currency,
including, but not limited to, the Euro, and, if such currency of denomination is a composite currency other than the Euro, the agency or organization, if any, responsible for overseeing such composite currency; 

(14)    the designation of the currency, currencies or currency units in which payment of the principal of, and interest
and premium, if any, on, the Securities of the Series will be made; 
 (15)    if payments of principal of, or interest
or premium, if any, on, the Securities of the Series are to be made in one or more currencies or currency units other than that or those in which such Securities are denominated, the manner in which the exchange rate with respect to such payments
will be determined; 
 (16)    the manner in which the amounts of payment of principal of, or interest and premium, if
any, on, the Securities of the Series will be determined, if such amounts may be determined by reference to an index based on a currency or currencies or by reference to a commodity, commodity index, stock exchange index or financial index; 

(17)    the provisions, if any, relating to any collateral provided for the Securities of the Series; 

(18)    any addition to or change in the covenants set forth in Articles 4 or 5 that applies to Securities of the Series;

 (19)    any addition to or change in the Events of Default which applies to any Securities of the Series, and any
change in the right of the Trustee or the requisite Holders of such Securities to declare the principal amount thereof due and payable pursuant to Section 6.2; 

(20)    the terms and conditions, if any, for conversion of the Securities into or exchange of the Securities for shares of
common stock or preferred stock of the Company that apply to Securities of the Series; 

  
 8 

 (21)    any depositories, interest rate calculation agents, exchange
rate calculation agents or other agents with respect to Securities of such Series if other than those appointed herein; 

(22)    the terms and conditions, if any, upon which the Securities shall be subordinated in right of payment to other
Indebtedness of the Company; 
 (23)    if applicable, that the Securities of the Series, in whole or any specified part,
shall be defeasible pursuant to Article 9; and 
 (24)    (24) any other terms of the Securities of the
Series (which terms shall not be inconsistent with the provisions of this Indenture, except as permitted by Section 8.1, but which may modify or delete any provision of this Indenture insofar as it applies to such Series). 

All Securities of any one Series need not be issued at the same time, and may be issued from time to time, consistent with the terms of
this Indenture, if so provided by or pursuant to the Board Resolution, supplemental indenture or Officers’ Certificate referred to above, however, the authorized principal amount of any Series may not be increased to provide for issuances
of additional Securities of such Series, unless otherwise provided in such Board Resolution, supplemental indenture or Officers’ Certificate. 

2.3    Execution and Authentication. 

The Securities shall be executed on behalf of the Company by two Officers of the Company or an Officer and an Assistant Secretary of the
Company. Each such signature may be either manual or facsimile. The Company’s seal may be impressed, affixed, imprinted or reproduced on the Securities and may be in facsimile form. 

If an Officer whose signature is on a Security no longer holds that office at the time the Security is authenticated, the Security shall
nevertheless be valid. 
 A Security shall not be valid until authenticated by the manual signature of the Trustee or an authenticating
agent. The signature shall be conclusive evidence that the Security has been authenticated under this Indenture. The Trustee shall at any time, and from time to time, authenticate Securities for original issue in the principal amount provided in the
Board Resolution, supplemental indenture hereto or Officers’ Certificate, upon receipt by the Trustee of a Company Order. Such Company Order may authorize authentication and delivery pursuant to oral or electronic instructions from the Company
or its duly authorized agent or agents, which oral instructions shall be promptly confirmed in writing. Each Security shall be dated the date of its authentication. 

The aggregate principal amount of Securities of any Series outstanding at any time may not exceed any limit upon the maximum principal
amount for such Series set forth in the Board Resolution, supplemental indenture hereto or Officers’ Certificate delivered pursuant to Section 2.2, except as provided in Section 2.8. 

  
 9 

 Prior to the issuance of Securities of any Series, the Trustee shall have received and
(subject to Section 7.1) shall be fully protected in relying on: (a) the Board Resolution, supplemental indenture hereto or Officers’ Certificate establishing the form of the Securities of that Series or of
Securities within that Series and the terms of the Securities of that Series or of Securities within that Series, (b) an Officers’ Certificate complying with Section 10.4, and (c) an Opinion of
Counsel complying with Section 10.4. 
 The Trustee shall have the right to decline to authenticate and deliver
any Securities of any Series: (a) if the Trustee, being advised in writing by outside counsel, determines that such action may not lawfully be taken; or (b) if the Trustee in good faith by its board of directors or trustees, executive
committee or a trust committee of directors and/or vice-presidents shall reasonably determine that such action would expose the Trustee to personal liability, or cause it to have a conflict of interest with respect to Holders of any then outstanding
Series of Securities. 
 The Trustee may appoint an authenticating agent acceptable to the Company to authenticate Securities. An
authenticating agent may authenticate Securities whenever the Trustee may do so. Any appointment shall be evidenced by an instrument signed by an authorized officer of the Trustee, a copy of which shall be furnished to the Company. Each reference in
this Indenture to authentication by the Trustee includes authentication by such agent. An authenticating agent has the same rights as an Agent to deal with the Company or an Affiliate of the Company. 

2.4    Registrar and Paying Agent. 

The Company shall maintain in each Place of Payment for any Series of Securities (i) an office or agency where such Securities may
be presented for registration of transfer or for exchange (“Registrar”), (ii) an office or agency where such Securities may be presented for payment (“Paying Agent”) (PROVIDED that the Company shall at all
times maintain a Paying Agent in the Borough of Manhattan, City of New York, State of New York (the “New York Paying Agent”), and PROVIDED, FURTHER, that at the option of the Company payment of interest may be made by check mailed
to the address of the Person entitled thereto as such address shall appear in the register for the Securities maintained by the Registrar), and (iii) an office or agency where notices and demands to or upon the Company in respect of the
Securities and this Indenture may be served (“Service Agent”). The Registrar shall keep a register of the Securities and of their transfer and exchange. The Company may have one or more
co-registrars and one or more additional paying agents. The Company shall give prompt written notice to the Trustee of the location, and any change in the location, of such office or agency. If at any time the
Company shall fail to maintain any such required office, or to furnish the Trustee with the address thereof, such presentations, surrenders, notices and demands may be made or served at the address of the Trustee as set forth in
Section 10.2. If the Company acts as Paying Agent, it shall segregate the money held by it for the payment of principal of, and interest and premium, if any, on, the Securities and hold it as a separate trust fund. The
Company may change any Paying Agent, Registrar, co-registrar or any other Agent without notice to any Securityholder. 

The Company may also from time to time designate one or more other offices or agencies where the Securities may be presented or surrendered
for any or all such purposes, and may from time to time rescind such designations; PROVIDED, HOWEVER, that no such designation or 

  
 10 

 
rescission shall in any manner relieve the Company of its obligation to maintain an office or agency in each Place of Payment for Securities of any Series for such purposes. The Company
hereby initially designates the Corporate Trust Office of the Trustee as such office of the Company. The Company shall give prompt written notice to the Trustee of such designation or rescission, and of any change in the location of any such other
office or agency. 
 The Company shall enter into an appropriate agency agreement with any Registrar or Paying Agent not a party to this
Indenture. The agreement shall implement the provisions of this Indenture that relate to such Agent. The Company shall notify the Trustee of the name and address of any such Agent. If the Company fails to maintain a Registrar or Paying Agent, or
agent for service of notices and demands, or fails to give the foregoing notice, the Trustee shall act as such. The Company hereby appoints the Trustee as the initial Registrar, Paying Agent and Service Agent for each Series unless another
Registrar, Paying Agent or Service Agent, as the case may be, is appointed prior to the time Securities of that Series are first issued. The Company designates , as the New York Paying Agent, with offices at. 

2.5    Paying Agent to Hold Assets in Trust. 

The Trustee as Paying Agent shall, and the Company shall require each Paying Agent other than the Trustee to agree in writing that each Paying
Agent shall, hold in trust for the benefit of the Holders of any Series of Securities or the Trustee all assets held by the Paying Agent for the payment of principal of, or interest or premium, if any, on, such Series of Securities
(whether such assets have been distributed to it by the Company or any other obligor on such Series of Securities), and the Company and the Paying Agent shall notify the Trustee in writing of any Default by the Company (or any other obligor on
such Series of Securities) in making any such payment. The Company at any time may require a Paying Agent to distribute all assets held by it to the Trustee and account for any assets disbursed, and the Trustee may, at any time during the
continuance of any payment default with respect to any Series of Securities, upon written request to a Paying Agent, require such Paying Agent to distribute all assets held by it to the Trustee and to account for any assets distributed. Upon
distribution to the Trustee of all assets that shall have been delivered by the Company to the Paying Agent, the Paying Agent shall have no further liability for such assets. 

2.6    Securityholder Lists. 

The Trustee shall preserve in as current a form as is reasonably practicable the most recent list available to it of the names and addresses
of Securityholders of each Series of Securities. If the Trustee is not the Registrar, the Company shall furnish to the Trustee as of each regular record date for the payment of interest on the Securities of a Series and before each related
Interest Payment Date, and at such other times as the Trustee may request in writing, a list in such form and as of such date as the Trustee may reasonably require of the names and addresses of Securityholders of each Series of Securities. 

2.7    Transfer and Exchange. 

When Securities of a Series are presented to the Registrar with a request to register the transfer thereof, the Registrar shall register
the transfer as requested if the requirements of 

  
 11 

 
applicable law are met, and when such Securities of a Series are presented to the Registrar with a request to exchange them for an equal principal amount of other authorized denominations of
Securities of the same Series, the Registrar shall make the exchange as requested. To permit transfers and exchanges, upon surrender of any Security for registration of transfer at the office or agency maintained pursuant to
Section 2.4, the Company shall execute and the Trustee shall authenticate Securities at the Registrar’s request. 

If Securities are issued as Global Securities, the provisions of Section 2.15 shall apply. 

All Securities issued upon any registration of transfer or exchange of Securities shall be the valid obligations of the Company, evidencing
the same debt, and entitled to the same benefits under this Indenture, as the Securities surrendered upon such registration of transfer or exchange. 

Every Security presented or surrendered for registration of transfer or for exchange shall (if so required by the Company or the Registrar or
a co-registrar) be duly endorsed, or be accompanied by a written instrument of transfer in form satisfactory to the Company and the Registrar or a co-registrar, duly
executed by the Holder thereof or his attorney duly authorized in writing. 
 Any exchange or transfer shall be without charge, except that
the Company may require payment by the Holder of a sum sufficient to cover any tax or other governmental charge that may be imposed in relation to a transfer or exchange, but this provision shall not apply to any exchange pursuant to
Section 2.11, 3.6 or 8.5. The Trustee shall not be required to register transfers of Securities of any Series, or to exchange Securities of any Series, for a period of 15 days before the record date for
selection for redemption of such Securities. The Trustee shall not be required to exchange or register transfers of Securities of any Series called or being called for redemption in whole or in part, except the unredeemed portion of such
Security being redeemed in part. 
 2.8    Replacement Securities. 

If a mutilated Security is surrendered to the Trustee, or if the Holder of a Security presents evidence to the satisfaction of the Company and
the Trustee that the Security has been lost, destroyed or wrongfully taken, the Company shall issue and the Trustee shall authenticate a replacement Security of the same Series and of like tenor and principal amount and bearing a number not
contemporaneously outstanding. An indemnity bond may be required by the Company or the Trustee that is sufficient in the reasonable judgment of the Company or the Trustee, as the case may be, to protect the Company, the Trustee or any Agent from any
loss which any of them may suffer if a Security is replaced. The Company may charge such Holder for the Company’s out-of-pocket expenses in replacing a Security,
including the fees and expenses of the Trustee. Every replacement Security shall constitute an original additional obligation of the Company, whether or not the destroyed, lost or stolen Security shall be at any time enforceable by anyone, and shall
be entitled to all the benefits of this Indenture equally and proportionately with any and all other Securities of that Series duly issued hereunder. 

  
 12 

 2.9    Outstanding Securities.

 Securities outstanding at any time are all Securities authenticated by the Trustee, except for those canceled by it, those delivered to
it for cancellation and those described in this Section 2.9 as not outstanding. 
 If a Security is replaced
pursuant to Section 2.8 (other than a mutilated Security surrendered for replacement), it ceases to be outstanding until the Company and the Trustee receive proof satisfactory to each of them that the replaced Security is
held by a bona fide purchaser. A mutilated Security ceases to be outstanding upon surrender of such Security and replacement thereof pursuant to Section 2.8. 

If a Paying Agent holds on a Redemption Date or the Stated Maturity money sufficient to pay the principal of, premium, if any, and accrued
interest on, Securities payable on that date, and is not prohibited from paying such money to the Holders thereof pursuant to the terms of this Indenture (PROVIDED, that if such Securities are to be redeemed, notice of such redemption has been duly
given pursuant to this Indenture or provision therefor satisfactory to the Trustee has been made), then on and after that date such Securities cease to be outstanding and interest on them ceases to accrue. 

A Security does not cease to be outstanding solely because the Company or an Affiliate holds the Security. 

2.10    When Treasury Securities Disregarded; Determination Of Holders Action. 

In determining whether the Holders of the required aggregate principal amount of the Securities of any Series have concurred in any
direction, waiver or consent, the Securities of any Series owned by the Company or any other obligor on such Securities, or by any Affiliate of any of them, shall be disregarded, except that for the purposes of determining whether the Trustee
shall be protected in relying on any such direction, waiver or consent, only Securities of such Series which the Trustee actually knows are so owned shall be so disregarded. Securities of such Series so owned which have been pledged in
good faith shall not be disregarded if the pledgee establishes to the satisfaction of the Trustee the pledgee’s right so to act with respect to the Securities of such Series and that the pledgee is not the Company or any other obligor on
the Securities of such Series, or an Affiliate of any of them. 
 2.11    Temporary
Securities. 
 Until definitive Securities are ready for delivery, the Company may prepare and execute, and the Trustee shall
authenticate, temporary Securities. Temporary Securities shall be substantially in the form, and shall carry all rights, of definitive Securities, but may have variations that the Company considers appropriate for temporary Securities. Without
unreasonable delay, the Company shall prepare and execute, and the Trustee shall authenticate, definitive Securities in exchange for temporary Securities without charge to the Holder. 

  
 13 

 2.12    Cancellation. 

All Securities surrendered for payment, redemption or registration of transfer or exchange, or for credit against any sinking fund payment,
shall, if surrendered to any Person other than the Trustee, be delivered to the Trustee for cancellation. The Company may at any time deliver to the Trustee for cancellation any Securities previously authenticated and delivered hereunder which the
Company may have acquired in any manner whatsoever, and may deliver to the Trustee (or to any other Person for delivery to the Trustee) for cancellation any Securities previously authenticated hereunder which the Company has not issued and sold. The
Registrar and the Paying Agent shall forward to the Trustee any Securities surrendered to them for transfer, exchange or payment. The Trustee or, at the direction of the Trustee, the Registrar or the Paying Agent, and no one else, shall cancel, and
at the written request of the Company shall dispose of, all Securities surrendered for transfer, exchange, payment or cancellation. If the Company shall acquire any of the Securities, such acquisition shall not operate as a redemption or
satisfaction of the Indebtedness represented by such Securities unless and until the same are surrendered to the Trustee for cancellation pursuant to this Section 2.12. No Securities shall be authenticated in lieu of or in
exchange for any Securities cancelled as provided in this Section 2.12, except as expressly permitted by this Indenture. 

2.13    Payment of Interest; Defaulted Interest; Computation of Interest. 

Except as otherwise provided as contemplated by Section 2.2 with respect to any Series of Securities, interest
on any Security which is payable, and is punctually paid or duly provided for, on any Interest Payment Date shall be paid to the Person in whose name that Security is registered at the close of business on the regular record date for such interest,
as provided in the Board Resolution, supplemental indenture hereto or Officers’ Certificate establishing the terms of such Series. 

If the Company defaults in a payment of interest on the Securities, it shall pay the defaulted amounts, plus any interest payable on defaulted
amounts pursuant to Section 4.1, to the Persons who are Securityholders on a subsequent special record date, which date shall be the 15th day next preceding the date fixed by the Company for the payment of defaulted
interest, or the next succeeding Business Day if such date is not a Business Day. At least 15 days before the special record date, the Company shall mail or cause to be mailed to each Securityholder, with a copy to the Trustee, a notice that states
the special record date, the payment date and the amount of defaulted interest, and interest payable on such defaulted interest, if any, to be paid. 

Except as otherwise specified as contemplated by Section 2.2 for Securities of any Series, interest on the
Securities of each Series shall be computed on the basis of a 360-day year of twelve 30-day months. 

2.14    Cusip Number. 

The Company in issuing the Securities may use one or more “CUSIP” numbers, and, if the Company does so, the Trustee shall use
the CUSIP number(s) in notices of redemption or exchange as a convenience to Holders, PROVIDED, that any such notice may state that no representation is made as to the correctness or accuracy of the CUSIP number(s) printed in the

  
 14 

 
notice or on the Securities, and that reliance may be placed only on the other identification numbers printed on the Securities, and that any such redemption or exchange shall not be affected by
any defect in or omission of any such numbers. 
 2.15    Provisions for Global
Securities. 
 (a)    A Board Resolution, a supplemental indenture hereto or an Officers’ Certificate shall
establish whether the Securities of a Series shall be issued in whole or in part in the form of one or more Global Securities, and the Depository for such Global Securities or Securities. 

(b)    Notwithstanding any provisions to the contrary contained in Section 2.7 and in addition thereto, if, and
only if the Depository (i) at any time is unwilling or unable to continue as Depository for such Global Security or ceases to be a clearing agency registered under the Exchange Act and (ii) a successor Depository is not
appointed by the Company within 90 days after the date the Company is so informed in writing or becomes aware of the same, the Company promptly will execute and deliver to the Trustee definitive Securities, and the Trustee, upon receipt of a Company
Request for the authentication and delivery of such definitive Securities (which the Company will promptly execute and deliver to the Trustee) and an Officers’ Certificate to the effect that such Global Security shall be so exchangeable, will
authenticate and deliver definitive Securities, without charge, registered in such names and in such authorized denominations as the Depository shall direct in writing (pursuant to instructions from its direct and indirect participants or otherwise)
in an aggregate principal amount equal to the principal amount of the Global Security with like tenor and terms. Upon the exchange of a Global Security for definitive Securities, such Global Security shall be canceled by the Trustee. Unless and
until it is exchanged in whole or in part for definitive Securities, as provided in this Section 2.15(b), a Global Security may not be transferred except as a whole by the Depository with respect to such Global Security to a nominee of
such Depository, by a nominee of such Depository to such Depository or another nominee of such Depository or by the Depository or any such nominee to a successor Depository or a nominee of such a successor Depository. 

(c)    Any Global Security issued hereunder shall bear a legend in substantially the following form: 

“This Security is a Global Security within the meaning of the Indenture hereinafter referred to, and is registered in the name of the
Depository or a nominee of the Depository. This Security is exchangeable for Securities registered in the name of a Person other than the Depository or its nominee only in the limited circumstances described in the Indenture, and may not be
transferred except as a whole by the Depository to a nominee of the Depository, by a nominee of the Depository to the Depository or another nominee of the Depository or by the Depository or any such nominee to a successor Depository or a nominee of
such a successor Depository.” 

  
 15 

 (d)    The Depository, as a Holder, may appoint agents and otherwise
authorize participants to give or take any request, demand, authorization, direction, notice, consent, waiver or other action which a Holder is entitled to give or take under the Indenture. 

(e)    Notwithstanding the other provisions of this Indenture, unless otherwise specified as contemplated by
Section 2.2, payment of the principal of, and interest and premium, if any, on, any Global Security shall be made to the Depository or its nominee in its capacity as the Holder thereof. 

(f)    Except as provided in Section 2.15(e) above, the Company, the Trustee and any Agent shall treat a Person
as the Holder of such principal amount of outstanding Securities of any Series represented by a Global Security as shall be specified in a written statement of the Depository (which may be in the form of a participants’ list for
such Series) with respect to such Global Security, for purposes of obtaining any consents, declarations, waivers or directions required to be given by the Holders pursuant to this Indenture, PROVIDED, that until the Trustee is so provided with a
written statement, it may treat the Depository or any other Person in whose name a Global Security is registered as the owner of such Global Security for the purpose of receiving payment of the principal of, and any premium and (subject to
Section 2.13) any interest on, such Global Security and for all other purposes whatsoever, and none of the Company, the Trustee or any agent of the Company or the Trustee shall be affected by notice to the contrary. 

2.16    Persons Deemed Owners. 

Prior to due presentment of a Security for registration of transfer, the Company, the Trustee, the Registrar and any agent of the Company, the
Registrar or the Trustee may treat the Person in whose name such Security is registered as the owner of such Security for the purpose of receiving payment of the principal of, and any premium and (subject to Section 2.13)
any interest on, such Security and for all other purposes whatsoever, and none of the Company, the Trustee, the Registrar or any agent of the Company, the Trustee or the Registrar shall be affected by notice to the contrary. 

ARTICLE 3 

REDEMPTION 
 
3.1    Notices to Trustee. 
 The Company may, with respect to any Series of Securities, reserve the
right to redeem and pay the Series of Securities, or may covenant to redeem and pay the Series of Securities or any part thereof, prior to the Stated Maturity thereof at such time and on such terms as provided for in such Securities or the
related Board Resolution, supplemental indenture or Officers’ Certificate. If a Series of Securities is redeemable and the Company elects to redeem all or part of such Series of Securities, it shall notify the Trustee of the
Redemption Date and the principal amount of Securities to be redeemed at least 45 days (unless a shorter notice shall be satisfactory to the Trustee) before the Redemption Date. Any such notice may be canceled at any time prior to notice of such
redemption being mailed to any Holder, and shall thereby be void and of no effect. 

  
 16 

 3.2    Selection by Trustee of
Securities to be Redeemed. 
 Unless otherwise indicated for a particular Series of Securities by a Board Resolution, a
supplemental indenture or an Officers’ Certificate, if fewer than all of the Securities of a Series are to be redeemed, the Trustee shall select the Securities of a Series to be redeemed pro rata, by lot or by any other method that
the Trustee considers fair and appropriate (unless the Company specifically directs the Trustee otherwise) and, if such Securities are listed on any securities exchange, by a method that complies with the requirements of such exchange. 

The Trustee shall make the selection from Securities of a Series outstanding and not previously called for redemption, and shall promptly
notify the Company in writing of the Securities selected for redemption and, in the case of any Security selected for partial redemption, the principal amount thereof to be redeemed at least 35 but not more than 60 days before the Redemption Date.
Securities of a Series in denominations of $1,000 may be redeemed only in whole. The Trustee may select for redemption portions of the principal of Securities of a Series that have denominations larger than $1,000. Securities of a
Series and portions of them it selects shall be in amounts of $1,000 or, with respect to Securities of any Series issuable in other denominations pursuant to Section 2.2(10), the minimum principal denomination for
each Series and integral multiples thereof. Provisions of this Indenture that apply to Securities called for redemption also apply to portions of Securities called for redemption. 

3.3    Notice of Redemption. 

Unless otherwise indicated for a particular Series by Board Resolution, a supplemental indenture hereto or an Officers’ Certificate,
at least 30 days, and no more than 60 days, before a Redemption Date, the Company shall mail, or cause to be mailed, a notice of redemption by first-class mail to each Holder of Securities to be redeemed at his or her last address as the same
appears on the registry books maintained by the Registrar. The notice shall identify the Securities to be redeemed and shall state: 

(1)    the Redemption Date; 

(2)    the redemption price, and that such redemption price shall become due and payable on the Redemption Date; 

(3)    if any Security of a Series is being redeemed in part, the portion of the principal amount of such Security of a
Series to be redeemed and that, after the Redemption Date and upon surrender of such Security of a Series, a new Security or Securities in principal amount equal to the unredeemed portion will be issued; 

(4)    the name and address of the Paying Agent; 

(5)    that Securities of a Series called for redemption must be surrendered to the Paying Agent to collect the redemption
price, and the place or places where each such Security is to be surrendered for such payment; 
 (6)    that, unless the
Company defaults in making the redemption payment, interest on the Securities of a Series called for redemption ceases to accrue on the Redemption Date, and the only remaining right of the Holders of such Securities is to receive payment of the
redemption price upon surrender to the Paying Agent of the Securities redeemed; 

  
 17 

 (7)    if fewer than all of the Securities of a Series are to be
redeemed, the identification of the particular Securities of a Series (or portion thereof) to be redeemed, as well as the aggregate principal amount of Securities of a Series to be redeemed and the aggregate principal amount of Securities of a
Series to be outstanding after such partial redemption. 
 (8)    the CUSIP number, if any, printed on the Securities
being redeemed; and 
 (9)    that no representation is made as to the correctness or accuracy of the CUSIP number, if
any, listed in such notice or printed on the Securities. 
 At the Company’s request, the Trustee shall give the notice of redemption
in the Company’s name and at the Company’s sole expense. 
 3.4    Effect
of Notice of Redemption. 
 Once the notice of redemption described in Section 3.3 is mailed, Securities of a
Series called for redemption become due and payable on the Redemption Date and at the redemption price, plus interest, if any, accrued to the Redemption Date. Upon surrender to the Trustee or Paying Agent, such Securities of a Series shall
be paid at the redemption price, plus accrued interest, if any, to the Redemption Date; PROVIDED, that if the Redemption Date is after a regular interest payment record date and on or prior to the next Interest Payment Date, the accrued interest
shall be payable to the Holder of the redeemed Securities registered on the relevant record date, as specified by the Company in the notice to the Trustee pursuant to Section 3.1. 

3.5    Deposit of Redemption Price. 

On or prior to the Redemption Date (but no later than 11:00 A.M. Eastern Time on such date), the Company shall deposit with the Paying
Agent money sufficient to pay the redemption price of and accrued interest, if any, on all Securities to be redeemed on that date other than Securities or portions thereof called for redemption on that date which have been delivered by the Company
to the Trustee for cancellation. 
 On and after any Redemption Date, if money sufficient to pay the redemption price of, and accrued
interest on, Securities called for redemption shall have been made available in accordance with the preceding paragraph and the Company and the Paying Agent are not prohibited from paying such moneys to Holders, the Securities called for redemption
will cease to accrue interest and the only right of the Holders of such Securities will be to receive payment of the redemption price of and, subject to the proviso in Section 3.4, accrued and unpaid interest on such
Securities to the Redemption Date. If any Security called for redemption shall not be so paid, interest will be paid, from the Redemption Date until such redemption payment is made, on the unpaid principal of the Security and any interest or
premium, if any, not paid on such unpaid principal, in each case, at the rate and in the manner provided in the Securities. 

  
 18 

 3.6    Securities Redeemed in
Part. 
 Upon surrender of a Security of a Series that is redeemed in part, the Company shall execute, and the Trustee shall
authenticate, for a Holder a new Security of the same Series equal in principal amount to the unredeemed portion of the Security surrendered. 

ARTICLE 4 

COVENANTS 
 
4.1    Payment of Securities. 
 The Company shall pay the principal of, and interest and premium, if any,
on, each Series of Securities on the dates and in the manner provided in such Securities and this Indenture. 
 An installment of
principal or interest shall be considered paid on the date it is due if the Trustee or Paying Agent holds on that date money designated for and sufficient to pay such installment and is not prohibited from paying such money to the Holders pursuant
to the terms of this Indenture or otherwise. 
 The Company shall pay interest on overdue principal, and overdue interest, to the extent
lawful, at the rate specified in the Series of Securities. 
 4.2    SEC
REPORTS. 
 The Company will deliver to the Trustee within 15 days after the filing of the same with the SEC, copies of the
quarterly and annual reports and of the information, documents and other reports, if any, which the Company is required to file with the SEC pursuant to Section 13 or 15(d) of the Exchange Act; PROVIDED, HOWEVER, that each such report or
document will be deemed to be so delivered to the Trustee if the Company files such report or document with the SEC through the SEC’s EDGAR database no later than the time such report or document is required to be filed with the SEC pursuant to
the Exchange Act. Notwithstanding that the Company may not be subject to the reporting requirements of Section 13 or 15(d) of the Exchange Act, the Company will file with the SEC, to the extent permitted, and provide the Trustee with, such
quarterly and annual reports and such information, documents and other reports specified in Sections 13 and 15(d) of the Exchange Act. The Company will also comply with the other provisions of TIA Section 314(a). 

4.3    Waiver of Stay, Extension or Usury Laws. 

The Company covenants (to the extent that it may lawfully do so) that it will not at any time insist upon, or plead (as a defense or
otherwise) or in any manner whatsoever claim or take the benefit or advantage of, any stay, extension, usury or other law which would prohibit or forgive the Company from paying all or any portion of the principal of, and/or interest and premium, if
any, on, the Securities as contemplated herein, wherever enacted, now or at any time hereafter in force, or which may affect the covenants or the performance of this Indenture; and the Company hereby expressly waives (to the extent that they may
lawfully do so) all benefit or 

  
 19 

 
advantage of any such law, and covenants that it will not hinder, delay or impede the execution of any power herein granted to the Trustee, but will suffer and permit the execution of every such
power as though no such law had been enacted. 
 4.4    Compliance
Certificate. 
 (a)    The Company shall deliver to the Trustee, within 120 days after the end of each fiscal
year of the Company, an Officers’ Certificate which complies with TIA Section 314(a)(4) stating that a review of the activities of the Company and its Subsidiaries during such fiscal year has been made under the supervision of
the signing Officers with a view to determining whether the Company has kept, observed, performed and fulfilled its obligations under this Indenture, and further stating, as to each such Officer signing such certificate, that to the best of his or
her knowledge the Company has kept, observed, performed and fulfilled each and every covenant contained in this Indenture and that there is no default in the performance or observance of any of the terms, provisions and conditions hereof (or, if a
Default or Event of Default shall have occurred, describing all such Defaults or Events of Default of which he or she may have knowledge and what action the Company is taking or proposes to take with respect thereto) and that to the best of his or
her knowledge no event has occurred and remains in existence by reason of which payments on account of the principal of, or interest or premium, if any, on, the Securities is prohibited, or if such event has occurred, a description of the event and
what action the Company is taking or proposes to take with respect thereto. 
 (b)    (i) If any Default or Event of
Default has occurred and is continuing or (ii) if any Holder seeks to exercise any remedy hereunder with respect to a claimed Default under this Indenture or the Securities, within five Business Days after the Company becoming aware of
such occurrence the Company shall deliver to the Trustee an Officers’ Certificate specifying such event, notice or other action and what action the Company is taking or proposes to take with respect thereto. 

4.5    Corporate Existence. 

Subject to Article 5, the Company shall do or cause to be done all things necessary to preserve and keep in full
force and effect its corporate existence, in accordance with the organizational documents (as the same may be amended from time to time) of the Company and the rights (charter and statutory), licenses and franchises of the Company; PROVIDED,
HOWEVER, that the Company shall not be required to preserve any such right, license or franchise, or its corporate existence, if the Board of Directors shall determine that the preservation thereof is no longer desirable in the conduct of the
business of the Company and that the loss thereof is not adverse in any material respect to the Holders. 

ARTICLE 5 

SUCCESSOR CORPORATION 
 
5.1    Limitation on Consolidation, Merger and Sale of Assets. 
 (a)    The Company will
not, in any transaction or series of transactions, merge or consolidate with or into, or sell, assign, convey, transfer, lease or otherwise dispose of all or substantially all of its properties and assets (as an entirety or substantially as an
entirety in one 

  
 20 

 
transaction or a series of related transactions), to any Person or Persons, unless at the time of and after giving effect thereto (i) either (A) if the transaction or series of
transactions is a merger or consolidation, the Company shall be the surviving Person of such merger or consolidation, or (B) the Person formed by such consolidation or into which the Company is merged or to which the properties and
assets of the Company are transferred (any such surviving Person or transferee Person being the “Surviving Entity”) shall be a corporation organized and existing under the laws of the United States of America, any state thereof or
the District of Columbia, or a corporation or comparable legal entity organized under the laws of a foreign jurisdiction and shall expressly assume by a supplemental indenture executed and delivered to the Trustee, in form reasonably satisfactory to
the Trustee, all of the obligations of the Company (including, without limitation, the obligation to pay the principal of, and premium and interest, if any, on, the Securities and the performance of the other covenants) under the Securities of each
Series and this Indenture, and in each case, this Indenture shall remain in full force and effect; and (ii) immediately before and immediately after giving effect to such transaction or series of transactions on a pro forma
basis (including, without limitation, any Indebtedness incurred or anticipated to be incurred in connection with or in respect of such transaction or series of transactions), no Default or Event of Default shall have occurred and be continuing. 

(b)    In connection with any consolidation, merger or transfer of assets contemplated by this Section 5.1, the
Company shall deliver, or cause to be delivered, to the Trustee, in form and substance reasonably satisfactory to the Trustee, an Officers’ Certificate and an Opinion of Counsel, each stating that such consolidation, merger or transfer, and the
supplemental indenture in respect thereto, comply with this Section 5.1, and that all conditions precedent herein provided for relating to such transaction or transactions have been complied with. 

5.2    Successor Person Substituted. 

Upon any consolidation, merger or transfer of all or substantially all of the assets of the Company in accordance with Section 5.1 above,
the successor corporation formed by such consolidation, or into which the Company is merged or to which such transfer is made, shall succeed to, and be substituted for, and may exercise every right and power of, the Company under this Indenture with
the same effect as if such successor corporation had been named as the Company herein, and thereafter (except with respect to any such transfer which is a lease) the predecessor corporation shall be relieved of all obligations and covenants under
this Indenture and the Securities. 
 ARTICLE 6 

DEFAULTS AND REMEDIES 
 
6.1    Events of Default. 
 “Events of Default,” wherever used herein with respect to
Securities of any Series, means any one of the following events, unless in the establishing Board Resolution, supplemental indenture or Officers’ Certificate, it is provided that such Series shall not have the benefit of said Event of
Default: 
 (1)    there is a default in the payment of any principal of, or premium, if any, on, the Securities when the
same becomes due and payable at Maturity, upon acceleration, redemption or otherwise; 

  
 21 

 (2)    there is a default in the payment of any interest on any Security
of a Series when the same becomes due and payable, and the Default continues for a period of 30 days; 
 (3)    the
Company defaults in the observance or performance of any other covenant in the Securities of a Series or in this Indenture for 60 days after written notice from the Trustee or the Holders of not less than 25% in the aggregate principal amount of the
Securities of such Series then outstanding, which notice must specify the Default, demand that it be remedied and state that the notice is a “Notice of Default”; 

(4)    the Company or any Significant Subsidiary pursuant to or within the meaning of any Bankruptcy Law: 

(A)    commences a voluntary case, 

(B)    consents to the entry of an order for relief against it in an involuntary case, 

(C)    consents to the appointment of a Custodian of it or for all or substantially all of its property, 

(D)    makes a general assignment for the benefit of its creditors, or 

(E)    generally is not paying its debts as they become due; 

(5)    a court of competent jurisdiction enters an order or decree under any Bankruptcy Law that: 

(A)    is for relief against the Company or any Significant Subsidiary in an involuntary case; 

(B)    appoints a Custodian of the Company or any Significant Subsidiary, or for all or substantially all of the property
of the Company or any Significant Subsidiary; or 
 (C)    orders the liquidation of the Company or any Significant
Subsidiary, and the order or decree remains unstayed and in effect for 90 consecutive days; or 
 (6)    any other Event
of Default provided with respect to Securities of that Series, which is specified in a Board Resolution, a supplemental indenture hereto or an Officers’ Certificate, in accordance with Section 2.2(19). 

  
 22 

 The term “Bankruptcy Law” means Title 11, U.S. Code, or any similar federal
or state law for the relief of debtors. The term “Custodian” means any receiver, trustee, assignee, liquidator or similar official under any Bankruptcy Law. 

The Trustee may withhold notice of any Default (except in the payment of the principal of, or interest or premium, if any, on, the Securities)
to the Holders of the Securities of any Series in accordance with Section 7.5. When a Default is cured, it ceases to exist. 

6.2    Acceleration. 

If an Event of Default with respect to Securities of any Series at the time outstanding (other than an Event of Default arising under
Section 6.1(4) or 6.1(5)) occurs and is continuing, the Trustee by written notice to the Company, or the Holders of not less than 25% in aggregate principal amount of the Securities of that Series then
outstanding by written notice to the Company and the Trustee, may declare that the entire principal amount of all the Securities of that Series then outstanding plus accrued and unpaid interest to the date of acceleration are immediately due
and payable, in which case such amounts shall become immediately due and payable; PROVIDED, HOWEVER, that after such acceleration but before a judgment or decree based on such acceleration is obtained by the Trustee, the Holders of a majority in
aggregate principal amount of the outstanding Securities of that Series may rescind and annul such acceleration and its consequences if (i) all existing Events of Default, other than the nonpayment of accelerated principal, interest or
premium, if any, that has become due solely because of the acceleration, have been cured or waived, (ii) to the extent the payment of such interest is lawful, interest on overdue installments of interest and overdue principal, which has become
due otherwise than by such declaration of acceleration, has been paid and (iii) the rescission would not conflict with any judgment or decree. No such rescission shall affect any subsequent Default or impair any right consequent thereto. In
case an Event of Default specified in Section 6.1(4) or 6.1(5) with respect to the Company occurs, such principal, premium, if any, and interest amount with respect to all of the Securities of that Series shall
be due and payable immediately without any declaration or other act on the part of the Trustee or the Holders of the Securities of that Series. 

6.3    Remedies. 

If an Event of Default with respect to Securities of any Series at the time outstanding occurs and is continuing, the Trustee may pursue
any available remedy by proceeding at law or in equity to collect the payment of the principal of, or interest and premium, if any, on, the Securities of that Series, or to enforce the performance of any provision of the Securities of that
Series or this Indenture. 
 The Trustee may maintain a proceeding even if it does not possess any of the Securities of that
Series or does not produce any of them in the proceeding. A delay or omission by the Trustee or any Securityholder in exercising any right or remedy accruing upon an Event of Default shall not impair the right or remedy or constitute a waiver
of or acquiescence in the Event of Default. No remedy is exclusive of any other remedy. All available remedies are cumulative to the extent permitted by law. 

  
 23 

 6.4    Waiver of Past Defaults and
Events of Default. 
 Subject to Sections 6.2, 6.7 and 8.2, the Holders of a majority in principal amount of the
Securities of any Series then outstanding have the right to waive any existing Default or Event of Default with respect to such Series or compliance with any provision of this Indenture (with respect to such Series) or the Securities of
such Series. Upon any such waiver, such Default with respect to such Series shall cease to exist, and any Event of Default with respect to such Series arising therefrom shall be deemed to have been cured for every purpose of this
Indenture; but no such waiver shall extend to any subsequent or other Default or Event of Default or impair any right consequent thereto. This Section 6.4 shall be in lieu of TIA Section 316(a)(1)(B), and TIA
Section 316(a)(1)(B) is hereby expressly excluded from this Indenture and Section 
as permitted by the TIA. 
 6.5    Control by Majority. 

Subject to Sections 6.2, 6.7 and 8.2, the Holders of a majority in principal amount of the Securities of any
Series then outstanding may direct the time, method and place of conducting any proceeding for any remedy available to the Trustee or exercising any trust or power conferred on the Trustee by this Indenture with respect to such Series. The
Trustee, however, may refuse to follow any direction that conflicts with law or this Indenture, or that the Trustee determines may be unduly prejudicial to the rights of another Securityholder, or that may involve the Trustee in personal liability;
PROVIDED, that the Trustee may take any other action deemed proper by the Trustee which is not inconsistent with such direction. This Section 6.5 shall be in lieu of TIA Section 316(a)(1)(A), and TIA
Section 316(a)(1)(A) is hereby expressly excluded from this Indenture and Section 
as permitted by the TIA. 
 6.6    Limitation on Suits. 

Subject to Section 6.7, a Securityholder may not institute any proceeding or pursue any remedy with respect to this
Indenture or the Securities of a Series unless: 
 (1)    the Holder gives to the Trustee written notice of a
continuing Event of Default with respect to the Securities of that Series; 
 (2)    the Holders of at least 25% in
aggregate principal amount of the Securities of such Series then outstanding make a written request to the Trustee to pursue the remedy; 

(3)    such Holder or Holders offer to the Trustee indemnity reasonably satisfactory to the Trustee against any loss,
liability or expense to be incurred in compliance with such request; 
 (4)    the Trustee does not comply with the
request within 60 days after receipt of the request and the offer of indemnity; and 
 (5)    no direction inconsistent
with such written request has been given to the Trustee during such 60-day period by the Holders of a majority in aggregate principal amount of the Securities of such Series then outstanding. 

  
 24 

 A Securityholder may not use this Indenture to prejudice the rights of another
Securityholder, or to obtain a preference or priority over another Securityholder. 

6.7    Rights of Holders to Receive Payment. 

Notwithstanding any other provision of this Indenture, the right of any Holder of a Security of a Series to receive payment of the
principal of, and interest and premium, if any, on, the Security of such Series on or after the respective due dates expressed in the Security of such Series, or to bring suit for the enforcement of any such payment on or after such respective
dates, is absolute and unconditional, and shall not be impaired or affected without the consent of the Holder. 
 
6.8    Collection Suit by Trustee. 
 If an Event of Default in payment of principal, interest or premium, if
any, specified in Section 6.1(1) or 6.1(2) with respect to Securities of any Series at the time outstanding occurs and is continuing, the Trustee may recover judgment in its own name and as trustee of an express
trust against the Company (or any other obligor on the Securities of that Series) for the whole amount of unpaid principal and premium, if any, and accrued interest remaining unpaid, together with interest on overdue principal and premium, if any,
and, to the extent that payment of such interest is lawful, interest on overdue installments of interest, in each case at the rate then borne by the Securities of that Series, and such further amounts as shall be sufficient to cover the costs and
expenses of collection, including the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel, as set forth in Section 7.7. 

6.9    Trustee May File Proofs of Claim. 

The Trustee may file such proofs of claim and other papers or documents, and take other actions (including sitting on a committee of
creditors), as may be necessary or advisable in order to have the claims of the Trustee (including any claim for the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel) and the Securityholders
allowed in any judicial proceedings relative to the Company (or any other obligor on the Securities), any of their respective creditors or any of their respective property, and the Trustee shall be entitled and empowered to collect and receive any
monies or other property payable or deliverable on any such claims, and to distribute the same after deduction of its charges and expenses to the extent that any such charges and expenses are not paid out of the estate in any such proceedings, and
any custodian in any such judicial proceeding is hereby authorized by each Securityholder to make such payments to the Trustee, and in the event that the Trustee shall consent to the making of such payments directly to the Securityholders, to pay to
the Trustee any amount due to it for the reasonable compensation, expenses, disbursements and advances of the Trustee, its agents and counsel, and any other amounts due the Trustee under Section 7.7. 

Nothing herein contained shall be deemed to authorize the Trustee to authorize or consent to, or accept or adopt on behalf of any
Securityholder, any plan of reorganization, arrangement, adjustment or composition affecting the Securities of a Series or the rights of any Holder thereof, or to authorize the Trustee to vote in respect of the claim of any Securityholder in
any such proceedings. 

  
 25 

 6.10    Priorities. 

If the Trustee collects any money pursuant to this Article 6, it shall pay out the money in the following order:

 FIRST: to the Trustee for amounts due under Section 7.7; 

SECOND: to Securityholders for amounts then due and unpaid for the principal of, and interest and premium, if any, on, the Securities in
respect of which, or for the benefit of which, such money has been collected, ratably, without preference or priority of any kind, according to the amounts due and payable on such Securities; for principal and any premium and interest, respectively;
and 
 THIRD: to the Company. 

The Trustee may fix a record date and payment date for any payment to Securityholders pursuant to this Section 6.10.
At least 15 days before such record date, the Trustee shall mail to each Securityholder a notice that states the record date, the payment date and amount to be paid. 

6.11    Undertaking for Costs. 

In any suit for the enforcement of any right or remedy under this Indenture, or in any suit against the Trustee for any action taken or
omitted by it as Trustee, a court in its discretion may require the filing by any party litigant in the suit of an undertaking to pay the costs of the suit, and the court in its discretion may assess reasonable costs, including reasonable
attorneys’ fees, against any party litigant in the suit, having due regard to the merits and good faith of the claims or defenses made by the party litigant. This Section 6.11 does not apply to a suit by the Trustee, a
suit by a Holder pursuant to Section 6.7 or a suit by Holders of more than 10% in principal amount of the Securities of a Series then outstanding. 

ARTICLE 7 

TRUSTEE 
 
7.1    Duties of Trustee. 
 (a)    If an Event of Default has occurred and is
continuing, the Trustee shall exercise such of the rights and powers vested in it by this Indenture and use the same degree of care and skill in their exercise as a prudent Person would exercise or use under the same circumstances in the conduct of
his own affairs. 
 (b)    Except during the continuance of an Event of Default: 

(1)    The Trustee need perform only those duties that are specifically set forth in this Indenture, and no covenants or
obligations shall be implied in this Indenture against the Trustee. 

  
 26 

 (2)    In the absence of bad faith on its part, the Trustee may
conclusively rely, as to the truth of the statements and the correctness of the opinions expressed therein, upon certificates or opinions furnished to the Trustee and conforming to the requirements of this Indenture, but, in the case of any such
certificates or opinions which by any provision hereof are specifically required to be furnished to the Trustee, the Trustee shall be under a duty to examine the same to determine whether or not they conform to the requirements of this Indenture.

 (c)    The Trustee may not be relieved from liability for its own negligent action, its own negligent failure to act
or its own willful misconduct, except that: 
 (3)    This paragraph does not limit the effect of paragraph (b) of
this Section 7.1. 
 (4)    The Trustee shall not be liable for any error of judgment made in good faith by
a Responsible Officer, unless it is proved that the Trustee was negligent in ascertaining the pertinent facts. 

(5)    The Trustee shall not be liable with respect to any action it takes or omits to take in good faith in accordance
with a direction received by it pursuant to Sections 6.2 and 6.5. 
 (d)    No provision of this
Indenture shall require the Trustee to expend or risk its own funds, or otherwise incur any financial liability, in the performance of any of its rights or powers if it shall have reasonable grounds for believing that repayment of such funds or
adequate indemnity satisfactory to it against such risk or liability is not reasonably assured to it. 
 (e)    Whether
or not therein expressly so provided, paragraphs (a), (b), (c) and (d) of this Section 7.1 shall govern every provision of this Indenture that in any way relates to the Trustee. 

(f)    The Trustee and Paying Agent shall not be liable for interest on any money received by either of them, except as the
Trustee and Paying Agent may agree in writing with the Company. Money held in trust by the Trustee need not be segregated from other funds except to the extent required by the law. 

(g)    The Paying Agent, the Registrar and any authenticating agent shall be entitled to the protections, immunities and
standard of care set forth in paragraphs (a), (b), (c), (d) and (f) of this Sections 7.1 and in 7.2 with respect to the Trustee. 

7.2    Rights of Trustee. 

(a)    Subject to Section 7.1: 

(1)    The Trustee may rely on, and shall be protected in acting or refraining from acting upon, any document reasonably
believed by it to be genuine and to have been signed or presented by the proper Person. The Trustee need not investigate any fact or matter stated in the document. 

  
 27 

 (2)    Before the Trustee acts or refrains from acting, it may require
an Officers’ Certificate or an Opinion of Counsel, or both, which shall conform to the provisions of Section 10.5. The Trustee shall be protected and shall not be liable for any action it takes or omits to take in good faith in
reliance on such certificate or opinion. 
 (3)    The Trustee may act through agents and attorneys, and shall not be
responsible for the misconduct or negligence of any agent appointed by it with due care. 
 (4)    The Trustee shall not
be liable for any action it takes or omits to take in good faith which it reasonably believes to be authorized or within its rights or powers. 

(5)    The Trustee may consult with counsel reasonably acceptable to the Trustee, which may be counsel to the Company, and
the advice or opinion of such counsel as to matters of law shall be full and complete authorization and protection from liability in respect of any action taken, omitted or suffered by it hereunder in good faith and in accordance with the advice or
opinion of such counsel. 
 (6)    The Trustee shall be under no obligation to exercise any of the rights or powers
vested in it by this Indenture at the request, order or direction of any of the Holders pursuant to the provisions of this Indenture, unless such Holders shall have offered to the Trustee reasonable security or indemnity against the costs, expenses
and liabilities which may be incurred therein or thereby. 
 (7)    The Trustee shall not be deemed to have knowledge of
any fact or matter (including, without limitation, a Default or Event of Default) unless such fact or matter is known to a Responsible Officer of the Trustee. 

(8)    Unless otherwise expressly provided herein or in the Securities of a Series or the related Board Resolution,
supplemental indenture or Officers’ Certificate, the Trustee shall not have any responsibility with respect to reports, notices, certificates or other documents filed with it hereunder, except to make them available for inspection, at
reasonable times, by Securityholders, it being understood that delivery of such reports, information and documents to the Trustee is for informational purposes only and the Trustee’s receipt of such shall not constitute constructive notice of
any information contained therein or determinable from information contained therein, including the Company’s compliance with any of its covenants hereunder (except as set forth in Section 4.4). 

7.3    Individual Rights Of Trustee. 

The Trustee in its individual or any other capacity may become the owner or pledgee of Securities, and may make loans to, accept deposits
from, perform services for or otherwise deal with the Company, or any Affiliate thereof, with the same rights it would have if it were not Trustee. Any Agent may do the same with like rights. The Trustee, however, shall be subject to
Sections 7.10 and 7.11. 

  
 28 

 7.4    Trustee’s
Disclaimer. 
 The Trustee makes no representation as to the validity or adequacy of this Indenture or the Securities (except that the
Trustee represents that it is duly authorized to execute and deliver this Indenture and authenticate the Securities and perform its obligations hereunder), and the Trustee shall not be accountable for the Company’s use of the proceeds from the
sale of Securities or any money paid to the Company pursuant to the terms of this Indenture, and the Trustee shall not be responsible for any statement in the Securities other than its certificates of authentication. 

7.5    Notice of Default. 

If a Default or an Event of Default occurs and is continuing with respect to the Securities of any Series, and if it is known to the Trustee,
the Trustee shall mail to each Securityholder of the Securities of that Series notice of the Default or the Event of Default, as the case may be, within 90 days after it occurs or, if later, after a Responsible Officer of the Trustee has
knowledge of such Default or Event of Default (except if such Default or Event of Default has been validly cured or waived before the giving of such notice). Except in the case of a Default or an Event of Default in payment of the principal of, or
interest or premium, if any, on, any Security of any Series, the Trustee may withhold the notice if and so long as the Board of Directors of the Trustee, the executive committee or any trust committee of such board and/or its Responsible Officers in
good faith determine(s) 
that withholding the notice is in the interests of the Securityholders of that Series. 
 7.6  
  Reports by Trustee to Holders. 
 If and to the extent required by the TIA, within 60 days after April 1 of each
year, commencing the April 1 following the date of this Indenture, the Trustee shall mail to each Securityholder a brief report dated as of such April 1 that complies with TIA Section 313(a). The Trustee also shall comply with TIA
Sections 313(b) and 313(c). 
 A copy of each report at the time of its mailing to Securityholders shall be filed with the SEC and any
stock exchange on which the Securities of that Series are listed. The Company shall promptly notify the Trustee when the Securities of any Series are listed on any stock exchange or any delisting thereof, and the Trustee shall comply with
TIA Section 313(d). 
 7.7    Compensation and Indemnity. 

The Company shall pay to the Trustee from time to time reasonable compensation for its services. The Trustee’s compensation shall not be
limited by any provision of law on compensation of a trustee of an express trust. The Company shall reimburse the Trustee within 45 days after receipt of request for all reasonable
out-of-pocket disbursements and expenses incurred or made by it in connection with its duties under this Indenture, including the reasonable compensation, disbursements
and expenses of the Trustee’s agents and counsel. 
 The Company shall indemnify the Trustee for, and hold it harmless against, any and
all loss or liability incurred by it in connection with the acceptance or performance of its duties under this Indenture including the reasonable costs and expenses of defending itself against any 

  
 29 

 
claim or liability in connection with the exercise or performance of any of its powers or duties hereunder. The Trustee shall notify the Company promptly of any claim asserted against the Trustee
for which it may seek indemnity. 
 The failure by the Trustee to so notify the Company shall not however relieve the Company of its
obligations. Notwithstanding the foregoing, the Company need not reimburse the Trustee for any expense or indemnify it against any loss or liability incurred by the Trustee through its negligence or bad faith. To secure the payment obligations of
the Company in this Section 7.7, the Trustee shall have a lien prior to the Securities of any Series on all money or property held or collected by the Trustee except such money or property held in trust to pay the
principal of, interest and premium, if any, on particular Securities of that Series. 
 When the Trustee incurs expenses or renders services
after an Event of Default specified in Section 6.1(4) or 6.1(5) occurs, the expenses and the compensation for the services are intended to constitute expenses of administration under any Bankruptcy Law. 

For purposes of this Section 7.7, the term “Trustee” shall include any trustee appointed pursuant
to this Article 7. 
 7.8    Replacement of
Trustee. 
 The Trustee may resign with respect to the Securities of one or more Series by so notifying the Company in
writing at least 90 days in advance of such resignation. 
 The Holders of a majority in principal amount of the outstanding Securities of
any Series may remove the Trustee with respect to that Series by notifying the removed Trustee in writing and may appoint a successor Trustee with respect to that Series with the consent of the Company, which consent shall not be
unreasonably withheld. The Company may remove the Trustee with respect to that Series at its election if: 

(1)    the Trustee fails to comply with, or ceases to be eligible under, Section 7.10; 

(2)    the Trustee is adjudged a bankrupt or an insolvent, or an order for relief is entered with respect to the Trustee,
under any Bankruptcy Law; 
 (3)    a Custodian or other public officer takes charge of the Trustee or its property; or

 (4)    the Trustee otherwise becomes incapable of acting. 

(5)    If the Trustee resigns or is removed, or if a vacancy exists in the office of Trustee, with respect to any Series of
Securities for any reason, the Company shall promptly appoint, by Board Resolution, a successor Trustee. 
 If a successor Trustee with
respect to the Securities of one or more Series does not take office within 60 days after the retiring Trustee resigns or is removed, the retiring Trustee, the Company or the Holders of at least 10% in principal amount of the outstanding
Securities of the applicable Series may petition any court of competent jurisdiction for the appointment of a successor Trustee. 

  
 30 

 If the Trustee with respect to the Securities of one or more Series fails to comply
with Section 7.10, any Securityholder of the applicable Series may petition any court of competent jurisdiction for the removal of the Trustee and the appointment of a successor Trustee. 

A successor Trustee shall deliver a written acceptance of its appointment to the retiring Trustee and to the Company. Immediately following
such delivery, (i) the retiring Trustee with respect to one or more Series shall, subject to its rights under Section 7.7, transfer all property held by it as Trustee with respect to such Series to the
successor Trustee, (ii) the resignation or removal of the retiring Trustee shall become effective and (iii) the successor Trustee with respect to such Series shall have all the rights, powers and duties of the Trustee under this
Indenture. A successor Trustee with respect to the Securities of one or more Series shall mail notice of its succession to each Securityholder of such Series. 

7.9    Successor Trustee by Consolidation, Merger or Conversion. 

If the Trustee, or any Agent, consolidates with, merges or converts into, or transfers all or substantially all of its corporate trust assets
to, another corporation, subject to Section 7.10, the successor corporation without any further act shall be the successor Trustee or Agent, as the case may be. 

7.10    Eligibility; Disqualification. 

This Indenture shall always have a Trustee who satisfies the requirements of TIA Sections 310(a)(1), (2) and (5) in every respect.
The Trustee (or in the case of a Trustee that is a Person included in a bank holding company system, the related bank holding company) shall have a combined capital and surplus of at least $100,000,000 as set forth in its most recent published
annual report of condition. The Trustee shall comply with TIA Section 310(b), including the provision in Section 310(b)(1). In addition, if the Trustee is a Person included in a bank holding company system, the Trustee, independently of
such bank holding company, shall meet the capital requirements of TIA Section 310(a)(2). If at any time the Trustee shall cease to be eligible in accordance with the provisions of this Section 7.10, it shall resign
immediately in the manner and with the effect specified in this Article 7. 

7.11    Preferential Collection of Claims Against Company. 

The Trustee shall comply with TIA Section 311(a), excluding any creditor relationship listed in TIA Section 311(b). A Trustee who
has resigned or been removed shall be subject to TIA Section 311(a) 
to the extent indicated therein. 
 7.12    Paying Agents. 

The Company shall cause each Paying Agent other than the Trustee to execute and deliver to it and the Trustee an instrument in which such
agent shall agree with the Trustee, subject to the provisions of this Section 7.12: 

(1)    that it will hold all sums held by it as agent for the payment of the principal of, or interest or premium, if any,
on, the Securities (whether such sums have been paid to it by the Company or by any obligor on the Securities) in trust for the benefit of Holders of the Securities or the Trustee; 

  
 31 

 (2)    that it will at any time during the continuance of any Event of
Default, upon written request from the Trustee, deliver to the Trustee all sums so held in trust by it together with a full accounting thereof; and 

(3)    that it will give the Trustee written notice within three Business Days after any failure of the Company (or by any
obligor on the Securities) in the payment of any installment of the principal of, or interest or premium, if any, on, the Securities when the same shall be due and payable. 

ARTICLE 8 

AMENDMENTS, SUPPLEMENTS AND WAIVERS 

8.1    Without Consent of Holders. 

The Company, when authorized by a Board Resolution, and the Trustee may amend or supplement this Indenture or the Securities of one or more
Series without notice to or consent of any Securityholder: 
 (1)    to comply with Section 5.1; 

(2)    to provide for certificated Securities in addition to uncertificated Securities; 

(3)    to comply with any requirements of the SEC under the TIA; 

(4)    to cure any ambiguity, defect or inconsistency, or to make any other change herein or in the Securities that does
not materially and adversely affect the rights of any Securityholder; 
 (5)    to provide for the issuance of, and
establish the form and terms and conditions of, Securities of any Series as permitted by this Indenture; or 
 (6)    to
evidence and provide for the acceptance of appointment hereunder by a successor Trustee with respect to the Securities of one or more Series, and to add to or change any of the provisions of this Indenture as shall be necessary to provide for or
facilitate the administration of the trusts hereunder by more than one Trustee. 
 The Trustee is hereby authorized to join with the Company
in the execution of any supplemental indenture authorized or permitted by the terms of this Indenture, and to make any further appropriate agreements and stipulations which may be therein contained, but the Trustee shall not be obligated to enter
into any such supplemental indenture which adversely affects its own rights, duties or immunities under this Indenture. 

  
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 8.2    With Consent of Holders.

 (a)    The Company, when authorized by a Board Resolution, and the Trustee may amend or supplement this Indenture or
the Securities of one or more Series with the written consent of the Holders of not less than a majority in aggregate principal amount of the outstanding Securities of such Series affected by such amendment or supplement without notice to any
Securityholder. The Holders of not less than a majority in aggregate principal amount of the outstanding Securities of each such Series affected by such amendment or supplement may waive compliance by the Company in a particular instance with any
provision of this Indenture or the Securities of such Series without notice to any Securityholder. Subject to Section 8.4, without the consent of each Securityholder affected, however, an amendment, supplement or waiver may not: 

(1)    reduce the amount of Securities whose Holders must consent to an amendment, supplement or waiver to this Indenture
or the Securities; 
 (2)    reduce the rate of, or change the time for payment of, interest on any Security; 

(3)    reduce the principal, or change the Stated Maturity, of any Security, or reduce the amount of, or postpone the date
fixed for, the payment of any sinking fund or analogous obligation; 
 (4)    make any Security payable in money other
than that stated in the Security; 
 (5)    change the amount or time of any payment required by the Securities, or
reduce the premium payable upon any redemption of the Securities, or change the time before which no such redemption may be made; 

(6)    waive a Default or Event of Default in the payment of the principal of, or interest or premium, if any, on, any
Security (except a rescission of acceleration of the Securities of any Series by the Holders of at least a majority in principal amount of the outstanding Securities of such Series and a waiver of the payment default that resulted from such
acceleration); 
 (7)    waive a redemption payment with respect to any Security, or change any of the provisions with
respect to the redemption of any Securities; 
 (8)    make any changes in Section 6.6 or this
Section 8.2, except to increase any percentage of Securities the Holders of which must consent to any matter; or 

(9)    take any other action otherwise prohibited by this Indenture to be taken without the consent of each Holder
affected thereby. 
 (b)    Upon the request of the Company, accompanied by a Board Resolution authorizing the execution
of any such supplemental indenture, and upon the receipt by the 

  
 33 

 
Trustee of evidence reasonably satisfactory to the Trustee of the consent of the Securityholders as aforesaid and of the documents described in Section 8.6, the Trustee shall join
with the Company in the execution of such supplemental indenture, unless such supplemental indenture affects the Trustee’s own rights, duties or immunities under this Indenture, in which case the Trustee may in its discretion, but shall not be
obligated to, enter into such supplemental indenture. 
 (c)    It shall not be necessary for the consent of the Holders
under this section to approve the particular form of any proposed amendment, supplement or waiver, but it shall be sufficient if such consent approves the substance thereof. 

After an amendment or supplement under this Section becomes effective, the Company shall mail to Securityholders a notice briefly describing
the amendment or supplement. Any failure of the Company to mail any such notice, or any defect therein, shall not, however, in any way impair or affect the validity of any supplemental indenture. 

8.3    Compliance With Trust Indenture Act. 

Every amendment to, or supplement of, this Indenture or the Securities shall comply with the TIA as then in effect. 

8.4    Revocation and Effect of Consents. 

Until an amendment, supplement, waiver or other action becomes effective, a consent to it by a Holder of a Security is a continuing consent
conclusive and binding upon such Holder and every subsequent Holder of the same Security or portion thereof, and of any Security issued upon the transfer thereof or in exchange therefor or in place thereof, even if notation of the consent is not
made on any such Security. Any such Holder or subsequent Holder, however, may revoke the consent as to his Security or portion of a Security, if the Trustee receives the notice of revocation before the date the amendment, supplement, waiver or other
action becomes effective. 
 The Company may, but shall not be obligated to, fix a record date for the purpose of determining the Holders
entitled to consent to any amendment, supplement or waiver, which record date shall be at least 30 days prior to the first solicitation of such consent. If a record date is fixed, then, notwithstanding the preceding paragraph, those Persons who were
Holders at such record date (or their duly designated proxies), and only such Persons, shall be entitled to consent to such amendment, supplement or waiver, or to revoke any consent previously given, whether or not such Persons continue to be
Holders after such record date. 
 After an amendment, supplement, waiver or other action becomes effective, it shall bind every
Securityholder, unless it makes a change described in any of clauses (1) through (9) of Section 8.2. In that case, the amendment, supplement, waiver or other action shall bind each Holder of a Security who has
consented to it and every subsequent Holder of a Security or portion of a Security that evidences the same debt as the consenting Holder’s Security; PROVIDED, that any such waiver shall not impair or affect the right of any Holder to receive
payment of the principal of, and interest and premium, if any, on, a Security, on or after the respective due dates expressed in such Security, or to bring suit for the enforcement of any such payment on or after such respective dates without the
consent of such Holder. 

  
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 8.5    Notation On or Exchange of
Securities. 
 If an amendment, supplement or waiver changes the terms of a Security of any Series, the Trustee may request the Holder
of such Security to deliver it to the Trustee. In such case, the Trustee shall place an appropriate notation on such Security about the changed terms and return it to the Holder. Alternatively, the Company, in exchange for such Security, may issue,
and the Trustee shall authenticate, a new security that reflects the changed terms. Failure to make the appropriate notation or issue a new Security shall not affect the validity and effect of such amendment, supplement or waiver. 

8.6    Trustee To Sign Amendments, Etc. 

The Trustee shall sign any amendment, supplement or waiver authorized pursuant to this Article 8 if the amendment,
supplement or waiver does not adversely affect the rights, duties, liabilities or immunities of the Trustee. If it does, the Trustee may, but need not, sign it. In signing or refusing to sign such amendment, supplement or waiver the Trustee shall be
entitled to receive and, subject to Section 7.1, shall be fully protected in relying upon an Officers’ Certificate and an Opinion of Counsel stating that such amendment, supplement or waiver is authorized or permitted
by this Indenture. The Company may not sign an amendment or supplement until the Board of Directors of the Company approves it. 
 
ARTICLE 9 
 DISCHARGE OF INDENTURE; DEFEASANCE 

9.1    Discharge of Indenture. 

The Company may terminate its obligations under the Securities of any Series and this Indenture with respect to such Series, except the
obligations referred to in the last paragraph of this Section 9.1, if there shall have been canceled by the Trustee, or delivered to the Trustee for cancellation, all Securities of such Series theretofore authenticated
and delivered (other than any Securities of such Series that are asserted to have been destroyed, lost or stolen and that shall have been replaced as provided in Section 2.8) and the Company has paid all sums payable
by it hereunder or deposited all required sums with the Trustee. 
 After such delivery the Trustee upon request shall acknowledge in a
writing prepared by or on behalf of the Company the discharge of the Company’s obligations under the Securities of such Series and this Indenture, except for those surviving obligations specified below. 

Notwithstanding the satisfaction and discharge of this Indenture, the obligations of the Company in Sections 7.7,
9.5 and 9.6 shall survive. 
 9.2    Legal Defeasance. 

The Company may at its option, by Board Resolution, be discharged from its obligations with respect to the Securities of any Series on
the date upon which the conditions set forth in Section 9.4 below are satisfied (hereinafter, “Legal Defeasance”). For this purpose, such Legal Defeasance means that the Company shall be deemed to have paid
and discharged the entire indebtedness represented by the Securities of such Series and to have satisfied all its other 

  
 35 

 
obligations under such Securities and this Indenture insofar as such Securities are concerned (and the Trustee, at the expense of the Company, shall, subject to
Section 9.6, execute proper instruments acknowledging the same, as are delivered to it by the Company), except for the following, which shall survive until otherwise terminated or discharged hereunder: (A) the rights
of Holders of outstanding Securities of such Series to receive solely from the trust funds described in Section 9.4 and as more fully set forth in such section, payments in respect of the principal of, and interest and
premium, if any, on, the Securities of such Series when such payments are due, (B) the Company’s obligations with respect to the Securities of such Series under Sections 2.4, 2.5, 2.6,
2.7, 2.8 and 2.9, (C) the rights, powers, trusts, duties and immunities of the Trustee hereunder (including claims of, or payments to, the Trustee under or pursuant to Section 7.7) and
(D) this Article 9. Subject to compliance with this Article 9, the Company may exercise its option under this Section 9.2 with respect to the Securities of any Series notwithstanding
the prior exercise of its option under Section 9.3 below with respect to the Securities of such Series. 

9.3    Covenant Defeasance. 

At the option of the Company, pursuant to a Board Resolution, the Company shall be released from its obligations with respect to the
outstanding Securities of any Series under Sections 4.2 through 4.5, inclusive, and Section 5.1, with respect to the outstanding Securities of such Series, on and after the date the
conditions set forth in Section 9.4 are satisfied (hereinafter, “Covenant Defeasance”). For this purpose, such Covenant Defeasance means that the Company may omit to comply with and shall have no liability
in respect of any term, condition or limitation set forth in any such specified section or portion thereof, whether directly or indirectly by reason of any reference elsewhere herein to any such specified Section or portion thereof or by reason
of any reference in any such specified section or portion thereof to any other provision herein or in any other document, but the remainder of this Indenture and the Securities of any Series shall be unaffected thereby. 

9.4    Conditions to Legal Defeasance or Covenant Defeasance. 

The following shall be the conditions to application of Section 9.2 or Section 9.3 to the
outstanding Securities of a Series: 
 (1)    the Company shall irrevocably have deposited or caused to be deposited with
the Trustee (or another trustee satisfying the requirements of Section 7.10 who shall agree to comply with the provisions of this Article 9 applicable to it) as funds in trust for the purpose of making the following payments,
specifically pledged as security for, and dedicated solely to, the benefit of the Holders of the Securities, (A) money in an amount, or (B) U.S. Government Obligations or Foreign Government Obligations which through the scheduled payment
of principal and interest in respect thereof in accordance with their terms will provide, not later than the due date of any payment, money in an amount, or (C) a combination thereof, sufficient, in the opinion of a nationally recognized firm
of independent public accountants expressed in a written certification thereof delivered to the Trustee, to pay and discharge, and which shall be applied by the Trustee (or other qualifying trustee) to pay and discharge, the principal of, and
accrued interest and premium, if any, on, the outstanding Securities of such Series at the Stated Maturity of such principal, interest or premium, if any, or on dates for payment and redemption of such principal, interest and premium, if any,
selected in accordance with the terms of this Indenture and of the Securities of such Series; 

  
 36 

 (2)    no Event of Default or Default with respect to the Securities of
such Series shall have occurred and be continuing on the date of such deposit, or shall have occurred and be continuing at any time during the period ending on the 91st day after the date of such deposit or, if longer, ending on the day following
the expiration of the longest preference period under any Bankruptcy Law applicable to the Company in respect of such deposit as specified in the Opinion of Counsel identified in paragraph (8) below (it being understood that this condition
shall not be deemed satisfied until the expiration of such period); 
 (3)    such Legal Defeasance or Covenant
Defeasance shall not cause the Trustee to have a conflicting interest for purposes of the TIA with respect to any securities of the Company; 

(4)    such Legal Defeasance or Covenant Defeasance shall not result in a breach or violation of, or constitute default
under, any other agreement or instrument to which the Company is a party or by which it is bound; 
 (5)    the Company
shall have delivered to the Trustee an Opinion of Counsel stating that, as a result of such Legal Defeasance or Covenant Defeasance, neither the trust nor the Trustee will be required to register as an investment company under the Investment Company
Act of 1940, as amended; 
 (6)    in the case of an election under Section 9.2, the Company shall have
delivered to the Trustee an Opinion of Counsel stating that (i) the Company has received from, or there has been published by, the Internal Revenue Service a ruling to the effect that or (ii) there has been a change in any applicable
Federal income tax law with the effect that, and such opinion shall confirm that, the Holders of the outstanding Securities of such Series or Persons in their positions will not recognize income, gain or loss for Federal income tax purposes solely
as a result of such Legal Defeasance and will be subject to Federal income tax on the same amounts, in the same manner, including as a result of prepayment, and at the same times as would have been the case if such Legal Defeasance had not occurred;

 (7)    in the case of an election under Section 9.3, the Company shall have delivered to the Trustee an
Opinion of Counsel to the effect that the Holders of the outstanding Securities of such Series will not recognize income, gain or loss for Federal income tax purposes as a result of such Covenant Defeasance, and will be subject to Federal income tax
on the same amounts, in the same manner and at the same times as would have been the case if such Covenant Defeasance had not occurred; 

(8)    the Company shall have delivered to the Trustee an Officers’ Certificate and an Opinion of Counsel, each
stating that all conditions precedent provided for in this Article 9 relating to either the Legal Defeasance under Section 9.2 or the Covenant Defeasance under Section 9.3 (as the case may be) have been complied
with; 

  
 37 

 (9)    the Company shall have delivered to the Trustee an Officers’
Certificate stating that the deposit under clause (1) was not made by the Company with the intent of defeating, hindering, delaying or defrauding any creditors of the Company or others; and 

(10)    the Company shall have paid, or duly provided for payment under terms mutually satisfactory to the Company and the
Trustee, all amounts then due to the Trustee pursuant to Section 7.7. 

9.5     Deposited Money And U.S. And Foreign Government Obligations To Be Held
In Trust; Other Miscellaneous Provisions. 
 All money, U.S. Government Obligations and Foreign Government Obligations (including the
proceeds thereof) deposited with the Trustee pursuant to Section 9.4 in respect of the outstanding Securities shall be held in trust and applied by the Trustee, in accordance with the provisions of such Securities and this
Indenture, to the payment, either directly or through any Paying Agent as the Trustee may determine, to the Holders of such Securities, of all sums due and to become due thereon in respect of principal, accrued interest and premium, if any, but such
money need not be segregated from other funds except to the extent required by law. 
 The Company shall pay and indemnify the Trustee
against any tax, fee or other charge imposed on or assessed against the U.S. Government Obligations and Foreign Government Obligations deposited pursuant to Section 9.4 or the principal, interest and premium, if any,
received in respect thereof other than any such tax, fee or other charge which by law is for the account of the Holders of the outstanding Securities. 

Anything in this Article 9 to the contrary notwithstanding, but subject to payment of any of its outstanding fees
and expenses, the Trustee shall deliver or pay to the Company from time to time upon Company Request any money, U.S. Government Obligations or Foreign Government Obligations held by the Trustee as provided in
Section 9.4which, in the opinion of a nationally-recognized firm of independent public accountants expressed in a written certification thereof delivered to the Trustee, are in excess of the amount thereof which would then
be required to be deposited to effect an equivalent Legal Defeasance or Covenant Defeasance. 

9.6    Reinstatement. 

If the Trustee or Paying Agent is unable to apply any money, U.S. Government Obligations or Foreign Government Obligations in accordance with
Sections 9.1, 9.2, 9.3 or 9.4 by reason of any legal proceeding or by reason of any order or judgment of any court or governmental authority enjoining, restraining or otherwise prohibiting such application,
the Company’s obligations under this Indenture and the Securities shall be revived and reinstated as though no deposit had occurred pursuant to this Article 9 until such time as the Trustee or Paying Agent is permitted
to apply all such money, U.S. Government Obligations or Foreign Government Obligations, as the case may be, in accordance with Sections 9.1, 9.2, 9.3 or 9.4; PROVIDED, HOWEVER, that if the Company has made any
payment of principal of, or accrued interest or premium, if any, on, any Securities because of the reinstatement of its obligations, the Company shall be subrogated to the rights of the Holders of such Securities to receive such payment from the
money, U.S. Government Obligations or Foreign Government Obligations held by the Trustee or Paying Agent. 

  
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 9.7    Moneys Held by Paying
Agent. 
 In connection with the satisfaction and discharge of this Indenture, all moneys then held by any Paying Agent under the
provisions of this Indenture shall, upon demand of the Company, be paid to the Trustee, or, if sufficient moneys have been deposited pursuant to Section 9.1, to the Company, and thereupon such Paying Agent shall be released
from all further liability with respect to such moneys. 
 9.8    Moneys Held by
Trustee. 
 Any moneys deposited with the Trustee or any Paying Agent or then held by the Company in trust for the payment of the
principal of, or interest or premium, if any, on, any Security that are not applied but remain unclaimed by the Holder of such Security for two years after the date upon which the principal of, or interest or premium, if any, on, such Security shall
have respectively become due and payable shall be repaid to the Company upon Company Request, or if such moneys are then held by the Company in trust, such moneys shall be released from such trust; and the Holder of such Security entitled to receive
such payment shall thereafter, as an unsecured general creditor, look only to the Company for the payment thereof, and all liability of the Trustee or such Paying Agent with respect to such trust money shall thereupon cease; PROVIDED, HOWEVER, that
the Trustee or any such Paying Agent, before being required to make any such repayment, may, at the expense of the Company, either mail to each Securityholder affected, at the address shown in the register of the Securities maintained by the
Registrar, or cause to be published once a week for two successive weeks, in a newspaper published in the English language, customarily published each Business Day and of general circulation in the City of New York, New York, a notice that such
money remains unclaimed and that, after a date specified therein, which shall not be less than 30 days from the date of such mailing or publication, any unclaimed balance of such moneys then remaining will be repaid to the Company. After payment to
the Company or the release of any money held in trust by the Company, Securityholders entitled to the money must look only to the Company for payment as general creditors, unless applicable abandoned property law designates another Person. 

ARTICLE 10 

MISCELLANEOUS 
 
10.1    Trust Indenture Act Controls. 
 If any provision of this Indenture limits, qualifies or conflicts
with another provision which is required to be included in this Indenture by the TIA, the required provision shall control. If any provision of this Indenture modifies or excludes any provision of the TIA which may be so modified or excluded, the
latter provision shall be deemed to apply to this Indenture as so modified or to be excluded, as the case may be. 

  
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 10.2    Notices. 

Any notice or communication shall be given in writing and delivered in Person, sent by facsimile (and receipt confirmed by telephone or
electronic transmission report), delivered by commercial courier service or mailed by first-class mail, postage prepaid, addressed as follows: 

If to the Company: 
 EyePoint
Pharmaceuticals, Inc. 
 480 Pleasant Street, Suite B300 

Watertown, MA 02472 
 Attn:
President and Chief Executive Officer 
 Facsimile: (617) 926-5000 

Copy to: 
 Hogan Lovells US LLP

 1735 Market Street, 23rd Floor 

Philadelphia, PA 19103-2799 
 Fax:
267-675-4601 
 Attention: Steven J. Abrams, Esq. 

If to the Trustee: 

____________________ 

____________________ 

____________________ 
 The
Company or the Trustee by written notice to the other may designate additional or different addresses for subsequent notices or communications. Any notice or communication to the Company or the Trustee shall be deemed to have been given or made as
of the date so delivered if personally delivered; when receipt is confirmed by telephone or electronic transmission report, if sent by facsimile; and three Business Days after mailing if sent by registered or certified mail, postage prepaid (except
that a notice of change of address shall not be deemed to have been given until actually received by the addressee). 
 Any notice or
communication mailed to a Securityholder shall be mailed to such Securityholder by first-class mail, postage prepaid, at such Securityholder’s address shown on the register kept by the Registrar. 

Failure to mail, or any defect in, a notice or communication to a Securityholder shall not affect its sufficiency with respect to other
Securityholders. If a notice or communication to a Securityholder is mailed in the manner provided above, it shall be deemed duly given, three Business Days after such mailing, whether or not the addressee receives it. 

In case by reason of the suspension of regular mail service, or by reason of any other cause, it shall be impossible to mail any notice as
required by this Indenture, then such method of notification as shall be made with the approval of the Trustee shall constitute a sufficient mailing of such notice. 

  
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 In the case of Global Securities, notices or communications to be given to Securityholders
shall be given to the Depository, in accordance with its applicable policies as in effect from time to time. 
 In addition to the manner
provided for in the foregoing provisions, notices or communications to Securityholders shall be given by the Company by release made to Reuters Economic Services and Bloomberg Business News. 

10.3    Communications by Holders With Other Holders. 

Securityholders of any Series may communicate pursuant to TIA Section 312(b) with other Securityholders of that Series or
any other Series with respect to their rights under this Indenture or the Securities of that Series or any other Series. The Company, the Trustee, the Registrar and any other Person shall have the protection of TIA Section 312(c).

 10.4    Certificate and Opinion as to Conditions Precedent. 

Upon any request or application by the Company to the Trustee to take any action under this Indenture, the Company shall furnish to the
Trustee: 
 (1)    an Officers’ Certificate (which shall include the statements set forth in
Section 10.5 below) stating that, in the opinion of the signers, all conditions precedent, if any, provided for in this Indenture relating to the proposed action have been complied with; and 

(2)    an Opinion of Counsel (which shall include the statements set forth in Section 10.5 below) stating that,
in the opinion of such counsel, all such conditions precedent have been complied with. 

10.5    Statement Required in Certificate and Opinion. 

Each certificate and opinion with respect to compliance with a condition or covenant provided for in this Indenture (other than pursuant to
Section 4.4) shall include: 
 (1)    a statement that the Person making such certificate or
opinion has read such covenant or condition; 
 (2)    a brief statement as to the nature and scope of the examination or
investigation upon which the statements or opinions contained in such certificate or opinion are based; 
 (3)    a
statement that, in the opinion of such Person, it or he has made such examination or investigation as is necessary to enable it or him to express an informed opinion as to whether or not such covenant or condition has been complied with; and 

(4)    a statement as to whether or not, in the opinion of such Person, such covenant or condition has been complied with.

  
 41 

 10.6    Rules by Trustee and
Agents. 
 The Trustee may make reasonable rules for action by or at meetings of Securityholders. The Registrar and Paying Agent
may make reasonable rules for their functions. 
 10.7    Business Days; Legal
Holidays; Place of Payment. 
 A “Business Day” is a day that is not a Legal Holiday. A “Legal
Holiday” is a Saturday, a Sunday, a federally-recognized holiday or a day on which banking institutions are not authorized or required by law, regulation or executive order to be open in the State of New York. 

If a payment date is a Legal Holiday at a Place of Payment, payment may be made at that place on the next succeeding day that is not a Legal
Holiday, and no interest shall accrue for the intervening period. “Place of Payment” means the place or places where the principal of, and interest and premium, if any, on, the Securities of a Series are payable as specified as
contemplated by Section 2.2. If the regular record date is a Legal Holiday, the record date shall not be affected. 

10.8    Governing Law. 

THIS INDENTURE AND THE SECURITIES SHALL BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE STATE OF NEW YORK, AS APPLIED TO
CONTRACTS MADE AND PERFORMED WITHIN THE STATE OF NEW YORK WITHOUT REGARD TO PRINCIPLES OF CONFLICTS OF LAW. 

10.9    No Adverse Interpretation of Other Agreements. 

This Indenture may not be used to interpret another indenture, loan, security or debt agreement of the Company or any Subsidiary thereof. No
such indenture, loan, security or debt agreement may be used to interpret this Indenture. 
 A director, officer, employee, stockholder or
incorporator, as such, of the Company shall not have any liability for any obligations of the Company under the Securities or the Indenture. Each Securityholder by accepting a Security waives and releases all such liability. Such waiver and release
are part of the consideration for the issuance of the Securities. 

10.10    Successors. 

All covenants and agreements of the Company in this Indenture and the Securities shall bind the Company’s successors and assigns, whether
so expressed or not. All agreements of the Trustee, any additional trustee and any Paying Agents in this Indenture shall bind their respective successors and assigns. 

10.11    Multiple Counterparts. 

The parties may sign multiple counterparts of this Indenture. Each signed counterpart shall be deemed an original, but all of them together
represent one and the same agreement. 

  
 42 

 10.12    Table of Contents,
Headings, Etc. 
 The table of contents, cross-reference sheet and headings of the Articles and Sections of this
Indenture have been inserted for convenience of reference only, are not to be considered a part hereof, and shall in no way modify or restrict any of the terms or provisions hereof. 

10.13    Severability. 

Each provision of this Indenture shall be considered separable, and if for any reason any provision which is not essential to the effectuation
of the basic purpose of this Indenture or the Securities shall be invalid, illegal or unenforceable, the validity, legality and enforceability of the remaining provisions shall not in any way be affected or impaired thereby, and a Holder shall have
no claim therefor against any party hereto. 
 10.14    Securities in a Foreign
Currency or in Euros. 
 Unless otherwise specified in a Board Resolution, a supplemental indenture hereto or an Officers’
Certificate delivered pursuant to Section 2.2 with respect to a particular Series of Securities, whenever for purposes of this Indenture any action may be taken by the Holders of a specified percentage in aggregate principal amount of
Securities of all Series or all Series affected by a particular action at the time outstanding and, at such time, there are outstanding Securities of any Series which are denominated in a coin or currency other than Dollars (including
Euros), then the principal amount of Securities of such Series which shall be deemed to be outstanding for the purpose of taking such action shall be that amount of Dollars that could be obtained for such amount at the Market Exchange Rate at
such time. For purposes of this Section 10.14, “Market Exchange Rate” shall mean the noon Dollar buying rate in New York City for cable transfers of that currency as published by the Federal Reserve Bank of New York; PROVIDED,
HOWEVER, in the case of Euros, Market Exchange Rate shall mean the rate of exchange determined by the Commission of the European Union (or any successor thereto) as published in the Official Journal of the European Union (such publication or any
successor publication, the “Journal”). If such Market Exchange Rate is not available for any reason with respect to such currency, the Trustee shall use, in its sole discretion and without liability on its part, such quotation of
the Federal Reserve Bank of New York or, in the case of Euros, the rate of exchange as published in the Journal, as of the most recent available date, or quotations or, in the case of Euros, rates of exchange from one or more major banks in New York
City or in the country of issue of the currency in question or, in the case of Euros, in Luxembourg or such other quotations or, in the case of Euros, rates of exchange as the Trustee, upon consultation with the Company, shall deem appropriate. The
provisions of this paragraph shall apply in determining the equivalent principal amount in respect of Securities of a Series denominated in currency other than Dollars in connection with any action taken by Holders of Securities pursuant to the
terms of this Indenture. 
 All decisions and determinations of the Trustee regarding the Market Exchange Rate or any alternative
determination provided for in the preceding paragraph shall be in the Trustee’s sole discretion, and shall, in the absence of manifest error, be conclusive to the extent permitted by law for all purposes and irrevocably binding upon the Company
and all Holders. 

  
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 10.15    Judgment Currency. 

The Company agrees, to the fullest extent that it may effectively do so under applicable law, that (a) if for the purpose of obtaining
judgment in any court it is necessary to convert the sum due in respect of the principal of, or interest or premium, if any, or other amount on, the Securities of any Series (the “Required Currency”) into a currency in which a
judgment will be rendered (the “Judgment Currency”), the rate of exchange used shall be the rate at which, in accordance with normal banking procedures, the Trustee could purchase in The City of New York the Required Currency with
the Judgment Currency on the day on which final unappealable judgment is entered, unless such day is not a Business Day, in which instance, the rate of exchange used shall be the rate at which, in accordance with normal banking procedures, the
Trustee could purchase in The City of New York the Required Currency with the Judgment Currency on the Business Day preceding the day on which final unappealable judgment is entered and (b) its obligations under this Indenture to make payments
in the Required Currency (i) shall not be discharged or satisfied by any tender or any recovery pursuant to any judgment (whether or not entered in accordance with subsection (a)) in any currency other than the Required Currency, except to the
extent that such tender or recovery shall result in the actual receipt, by the payee, of the full amount of the Required Currency expressed to be payable in respect of such payments, (ii) shall be enforceable as an alternative or additional
cause of action for the purpose of recovering in the Required Currency the amount, if any, by which such actual receipt shall fall short of the full amount of the Required Currency so expressed to be payable and (iii) shall not be affected by
judgment being obtained for any other sum due under this Indenture. 
 10.16    Force
Majeure. 
 In no event shall the Trustee be responsible or liable for any failure or delay in the performance of its obligations
hereunder arising out of or caused by, directly or indirectly, forces beyond its control, including, without limitation, strikes, work stoppages, accidents, acts of war or terrorism, civil or military disturbances, nuclear or natural catastrophes or
acts of God, and interruptions, loss or malfunctions of utilities, communications or computer (software and hardware) services, it being understood that the Trustee shall use reasonable best efforts which are consistent with accepted practices in
the banking industry to resume performance as soon as practicable under the circumstances. 

10.17    U.S.A. Patriot Act. 

The parties hereto acknowledge that in accordance with Section 326 of the U.S.A. Patriot Act, the Trustee is required to obtain, verify,
and record information that identifies each person or legal entity that establishes a relationship or opens an account with the Trustee. The parties to this Indenture agree that they will provide the Trustee with such information as it may request
in order for the Trustee to satisfy the requirements of the U.S.A. Patriot Act. 

  
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 ARTICLE 11 

SINKING FUNDS 
 
11.1    Applicability of Article. 
 The provisions of this Article shall be applicable to any sinking
fund for the retirement of the Securities of a Series if so provided by the terms of such Securities pursuant to Section 2.2 and except as otherwise permitted or required by any form of Security of such Series issued pursuant to this
Indenture. The minimum amount of any sinking fund payment provided for by the terms of the Securities of any Series is herein referred to as a “mandatory sinking fund payment” and any other amount provided for by the terms of
Securities of such Series is herein referred to as a “optional sinking fund payment.” If provided for by the terms of Securities of any Series, the cash amount of any sinking fund payment may be subject to reduction as provided in
Section 11.2. Each sinking fund payment shall be applied to the redemption of Securities of any Series as provided for by the terms of the Securities of such Series. 

11.2    Satisfaction of Sinking Fund Payments with Securities. 

The Company may, in satisfaction of all or any part of any sinking fund payment with respect to the Securities of any Series to be made
pursuant to the terms of such Securities (1) deliver outstanding Securities of such Series to which such sinking fund payment is applicable (other than any of such Securities previously called for mandatory sinking fund redemption) and
(2) apply as credit Securities of such Series to which such sinking fund payment is applicable and which have been repurchased by the Company or redeemed either at the election of the Company pursuant to the terms of such Series of
Securities (except pursuant to any mandatory sinking fund) or through the application of permitted optional sinking fund payments or other optional redemptions pursuant to the terms of such Securities, provided that such Securities have not been
previously so credited. Such Securities shall be received by the Trustee, together with an Officers’ Certificate with respect thereto, not later than 15 days prior to the date on which the Trustee begins the process of selecting Securities for
redemption, and shall be credited for such purpose by the Trustee at the price specified in such Securities for redemption through operation of the sinking fund and the amount of such sinking fund payment shall be reduced accordingly. If as a result
of the delivery or credit of Securities in lieu of cash payments pursuant to this Section 11.2, the principal amount of Securities of such Series to be redeemed in order to exhaust the aforesaid cash payment shall be less than $100,000,
the Trustee need not call Securities of such Series for redemption, except upon receipt of a Company Order that such action be taken, and such cash payment shall be held by the Trustee or a Paying Agent and applied to the next succeeding
sinking fund payment, provided, however, that the Trustee or such Paying Agent shall from time to time upon receipt of a Company Order pay over and deliver to the Company any cash payment so being held by the Trustee or such Paying Agent upon
delivery by the Company to the Trustee of Securities of that Series purchased by the Company having an unpaid principal amount equal to the cash payment required to be released to the Company. 

11.3    Redemption of Securities for Sinking Fund. 

Not less than 45 days (unless otherwise indicated in the Board Resolution, supplemental indenture hereto or Officers’ Certificate in
respect of a particular Series of Securities) prior to each sinking fund payment date for any Series of Securities, the Company will deliver to the Trustee an Officers’ Certificate specifying the amount of the next ensuing mandatory
sinking 

  
 45 

 
fund payment for that Series pursuant to the terms of that Series, the portion thereof, if any, which is to be satisfied by payment of cash and the portion thereof, if any, which is to be
satisfied by delivering and crediting of Securities of that Series pursuant to Section 11.2, and the optional amount, if any, to be added in cash to the next ensuing mandatory sinking fund payment, and the Company shall thereupon be
obligated to pay the amount therein specified. Not less than 30 days (unless otherwise indicated in the Board Resolution, Officers’ Certificate or supplemental indenture in respect of a particular Series of Securities) before each such
sinking fund payment date the Securities to be redeemed upon such sinking fund payment date will be selected in the manner specified in Section 3.2 and the Company shall send or cause to be sent a notice of the redemption thereof to be given in
the name of and at the expense of the Company in the manner provided in and in accordance with Section 3.3. Such notice having been duly given, the redemption of such Securities shall be made upon the terms and in the manner stated in Sections
3.4, 3.5 and 3.6. 
 IN WITNESS WHEREOF, the parties hereto have caused this Indenture to be duly executed, and their respective corporate
seals to be hereunto affixed and attested, all as of the day and year first above written. 
  

			
	EYEPOINT PHARMACEUTICALS, INC.

 
			
		
	By:	 	 
	Name:	 	 
	Title:	 	 
	
	[Name of Trustee]
		
	By:	 	 
	Name:	 	 
	Title:	 	 
		
	By:	 	 
	Name:	 	 
	Title:	 	 

  
 46

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