Document:

<PAGE>
                                                                   EXHIBIT 10.19

Portions of the following exhibit have been omitted under a request for
confidential treatment under Section 24b-2 of the Securities Act of 1934.
Locations of these omitted portions is denoted by the following legend. [* *]

                                SUPPLY AGREEMENT

         THIS SUPPLY AGREEMENT (this "Agreement"), entered into as of the 7th
day of March, 2003, is between ROCKWELL MEDICAL TECHNOLOGIES, INC., a Michigan
corporation ("ROCKWELL"), and DAVITA INC. ("DAVITA"), a Delaware corporation.

                                    RECITALS

         A. ROCKWELL is in the business of manufacturing and selling the
dialysis products known as Dri-Sate(R) Dry Acid, Liquid Acid, Powder Bicarbonate
and SteriLyte(R) Liquid Bicarbonate, and the cleaning agents, as more
particularly described on Exhibits A and B attached hereto and incorporated
herein by this reference (the "Products");

         B. DAVITA is in the business of owning (in whole or in part) or
managing and operating dialysis clinics, which business requires the purchase
and use of supplies such as the Products; and

         C. DAVITA desires to purchase the Products listed on Exhibits A and B
from ROCKWELL, on the terms and conditions contained in this Agreement.

         Therefore, the parties hereby agree as follows:

         1. Purchase of Products. During the Term (as hereinafter defined),
ROCKWELL will sell to DAVITA such Products and in such quantities as DAVITA may
from time to time order, in the states and at the prices as set forth on Exhibit
A and Exhibit B (hereinafter defined as the "Territory"). Other states may be
added to the Territory, and other ancillary dialysis products may be added to
the Products to be sold hereunder, during the Term of this Agreement, but only
upon the mutual written consent of both parties. ROCKWELL understands and
acknowledges that DAVITA has not promised or committed to purchase any
particular quantity of any of the Products or any particular percentage of its
requirements for items such as the Products except as set forth in Section 4.

         2. Term. The term of this Agreement shall commence March 7, 2003 and
continue for a period of two years (the "Term"), unless sooner terminated in
accordance with section 9 below. Upon its expiration, the Term of the Agreement
may be extended annually upon the written agreement of both parties.

         3. Purchase Price. The purchase price for the Products shall initially
be as set forth on Exhibit A. The purchase price for Dri-Sate(R) Dry Acid may be
reduced in accordance with the provisions in section 4 below, in which case the
purchase price for Dri-Sate(R) Dry Acid shall

                                       1

<PAGE>

be as set forth on Exhibit B. Except as set forth on Exhibit C, DAVITA shall not
be liable for other charges or fees, including without limitation service
charges, handling charges, shipping charges, assessments or expenses, nor shall
DAVITA be liable for any taxes other than sales taxes. DAVITA shall not be
liable for any excise, gross receipts, gross earnings, gross value, property,
income taxes measured on ROCKWELL'S income, or any other taxes.

         4. Conversion to Concentrate. During the Term of this Agreement, DAVITA
agrees to use its best efforts to convert approximately one hundred (100) of its
dialysis clinics, which are not currently purchasing Products from ROCKWELL and
which are located in the Territory ("Converted Clinics"), to ROCKWELL'S
Dri-Sate(R) Dry Acid and bicarbonate concentrate products, [*

                                             *]. All Converted Clinics converted
within the first twelve (12) months of this Agreement will purchase all of their
requirements of Products from ROCKWELL (other than Cleaning Agents) from the
date they are converted for a minimum of twelve (12) months. DAVITA and
ROCKWELL, upon mutual agreement, will determine the rate, timing, and selection
of clinics to participate in such conversion. Once one hundred (100) clinics are
successfully converted, and so long as 100 clinics continue to buy all of their
requirements of Products from ROCKWELL, Rockwell shall reduce the prices for its
Dri-Sate(R) Dry Acid to the prices shown on Exhibit B. If, after one year from
the date of this Agreement, less than one hundred (100) clinics are successfully
converted, Rockwell shall increase the prices for its Dri-Sate(R) Dry Acid [**]
above the prices shown on Exhibit A. Any DAVITA dialysis clinic that cannot
accommodate Dri-Sate(R) or in which Dri-Sate(R) cannot be utilized may purchase
liquid acid from ROCKWELL, and will be included for purposes of determining
whether one hundred (100) clinics have converted. Acute facilities are not
included in the above referenced one hundred (100) clinics, however, they can
also purchase the Products from ROCKWELL at the same prices.

         5. Delivery Limitations. The Purchase Prices set forth on Exhibits A
and B cover standard shipping within the Territory for all Products, F.O. B.
Destination. Notwithstanding the foregoing, all orders for Products to be
shipped by ROCKWELL shall be subject to ROCKWELL's minimum purchase requirements
and other shipping requirements set forth on Exhibit C. In the event DAVITA
requires Products to be shipped outside of the Territory or requires some
deviation from the minimum purchase requirements and other shipping requirements
set forth on Exhibit C, ROCKWELL and DAVITA must agree beforehand on any
increase in the purchase price with respect to such Products to cover any
additional delivery costs. Any Products shipped internationally shall be shipped
FOB from any ROCKWELL plant.

         6. Delivery Time. With respect to any order for Products to be
delivered within the Territory, ROCKWELL shall deliver such Products to DAVITA
in accordance with ROCKWELL's written delivery guidelines attached as a part of
Exhibit C. ROCKWELL shall

                                       2

<PAGE>

provide accurate and on-time deliveries of all orders placed, and shall provide
DAVITA with reasonable access to one or more dedicated Customer Service
personnel who shall be available to promptly respond to DAVITA inquiries and to
perform routine service and maintenance, as well as all appropriate repairs, on
the Mixers when ordered by DAVITA. ROCKWELL understands and agrees that the
provision of such services in the highest professional manner constitutes an
essential term of this Agreement, without which the parties would not have
entered into this Agreement, and the failure of ROCKWELL to meet any such
standards shall constitute a breach of this Agreement.

         7. Payment Terms. All purchases by DAVITA of Products pursuant to this
Agreement shall be paid on terms net 30 days. [*
                                                 *]. DAVITA may withhold payment
on the portion of any invoice for which DAVITA has a bona fide dispute if it (a)
pays all undisputed amounts; (b) notifies ROCKWELL that it is disputing charges;
and (c) provides a reconciliation of charges and documentation necessary to
support its claimed adjustment. All other purchase terms and conditions shall be
as set forth on Exhibit C.

         8. Failure to Perform Supply Obligation. In the event ROCKWELL cannot
supply or does not deliver any Product(s) (whether as a result of force majeure
or otherwise) within and for the time period required by DAVITA, to any clinics
that are, as of the date of this Agreement, already purchasing Products from
ROCKWELL or that later do so under section 4 above, ROCKWELL agrees that it
shall give notice as promptly as is practicable under the circumstances to
DAVITA, unless an order of a regulatory agency or other action arising out of
patient safety concerns requires the giving of shorter notice. In the event
ROCKWELL is unable to fulfill DAVITA'S orders within the Territory at any time
during the Term of this Agreement, DAVITA may, as its sole and exclusive remedy,
upon prior notice to ROCKWELL, seek other suppliers to fill purchase orders for
some or all Products until DAVITA receives notification from ROCKWELL that
ROCKWELL will again be able to deliver Products. If DAVITA is required to
purchase Products from a third party under this Section 8, ROCKWELL will provide
DAVITA with a purchase credit equal to the difference, if any, in the then
current purchase prices for the Products which ROCKWELL was unable to deliver,
and the purchase prices DAVITA is reasonably required to pay, including
legitimate freight charges incurred, in order to obtain similar or equivalent
products from a different supplier(s).

         9. Termination Default. The following shall constitute a termination
default ("Termination Default") hereunder:

            a. substantial breach of the terms of this Agreement (other than a
failure to perform described in Section 8 for which a sole and exclusive remedy
is provided), which breach is not cured, corrected or otherwise resolved within
thirty (30) days after written notice by the non-breaching party (setting forth
the particulars of the alleged breach) to the breaching party. A "substantial
breach" shall include a failure to perform any material obligation hereunder,
including without limitation a failure to pay any amount due hereunder or under
any purchase

                                       3

<PAGE>

order issued hereunder when due, other than amounts which DAVITA disputes in
good faith; or

            b. (i) the institution by or against a party or its assets of
insolvency, receivership or bankruptcy proceedings or any other material
proceedings for the settlement of such party's debts, (ii) a party's making a
general assignment for the benefit of its creditors, or (iii) a party's
dissolution.

         10. Termination. Upon the occurrence of a Termination Default
hereunder, and only upon such occurrence, the non-defaulting party may terminate
this Agreement immediately upon written notice to the defaulting party.
Termination of this Agreement shall not relieve either party of obligations
incurred prior to the effective date of termination, including without
limitation obligations of payment of monies or credits owed at the time of such
termination. The provisions of this Section 10 and of Sections 13
(Confidentiality), 14 (Warranties), 15 (Indemnification and Insurance), 20
(Choice of law), and 21 (Attorney fees) shall survive any expiration or
termination of this Agreement.

         11. Product Addition. Any products other than those set forth on
Exhibits A and B may be included under the terms hereof, but only upon the
mutual, written agreement of the parties. Prices for such products shall be
negotiated by the parties in good faith and the agreed prices shall be confirmed
in writing and made a part of this Agreement.

         12. Training. ROCKWELL agrees to furnish, at no additional fee, cost or
expense, complete and appropriate training regarding the use and maintenance of
the Dri-Sate(R) Acid Mixer, to such number of DAVITA personnel as DAVITA shall
designate. Such training shall be provided on the premises of each clinic, or if
acceptable, at one clinic with multiple trainees, which has converted to
Dri-Sate(R) Acid, on such dates and at such times as DAVITA shall reasonably
request.

         13. Confidentiality. Both ROCKWELL and DAVITA agree that this Agreement
represents and contains confidential information which shall not be disclosed to
any third party, or otherwise made public, without prior written authorization
of the other party, except where it is required by law or pursuant to subpoena
or court or administrative order. Neither party shall make any public
announcement (including, without limitation, any press release or other similar
announcement) of the matters described in this Agreement without the express
prior written consent of the other party. Notwithstanding the foregoing, either
party may disclose the terms and the existence of this Agreement to the extent
that is necessary to fulfill its obligations under state or federal securities
laws, or under any exchange or market upon which the security of such party are
traded. In the event of such disclosure, both parties must agree to the language
of the disclosure. Each party agrees not to use, release, publish or distribute
any materials or information (including but not limited to advertising and
promotional materials) containing the names, tradenames, or trademarks of the
other party without the express prior written consent of such other party. Each
party and its agents shall keep confidential and shall hold in trust for the
sole benefit of the other, and not disclose or use except in connection with the
performance of its

                                       4

<PAGE>

obligations hereunder, any and all trade secrets and other proprietary and
confidential information regarding the other's business, customers, financial
condition, practices or procedures, whether disclosed by the other or discovered
by it. Any breach of these provisions would cause irreparable harm to the other
party, and each party agrees that it will not interpose the lack of such
irreparable harm in any action to enforce these obligations.

         14. Warranties. Each party represents and warrants to the other that
this Agreement (a) has been duly authorized, executed and delivered by it, and
(b) constitutes a valid, legal, and binding agreement enforceable against it in
accordance with its terms. ROCKWELL covenants and agrees that no Product
delivered hereunder is or will be adulterated or misbranded within the meaning
of the Federal Food, Drug and Cosmetic Act, as amended, or within the meaning of
any applicable state or municipal law, or is or will be a product which may not
be introduced into interstate commerce. ROCKWELL represents and warrants that it
has all rights, licenses, permits and consents necessary to sell the Products to
DAVITA (and to provide the Mixers to DAVITA), and to perform its obligations
hereunder. ROCKWELL further warrants that the Products purchased pursuant to
this Agreement (a) shall be manufactured in accordance with their packaging; (b)
are and shall be manufactured, handled, stored and transported in accordance
with all applicable United States, state and local laws and regulations
pertaining thereto, including without limitation, the Federal Food, Drug, and
Cosmetic Act and implementing regulations and FDA-approved Good Manufacturing
Practices, and meet all specifications for effectiveness, safely and reliability
as required by the United States Food and Drug Administration ("FDA"), and (c)
when used in accordance with the directions on the labeling, are and shall be
fit for the purposes and indications described in the labeling. ROCKWELL
warrants that all Products purchased hereunder (as well as the Mixers) will be
of the kind and quantity specified herein, will be free of defects, and will be
within AAMI standards. ROCKWELL shall service, maintain and repair the Mixers,
and shall provide all parts and labor in connection therewith, without any
additional fee or charge to DAVITA.

         15. Indemnification and Insurance.

         a. ROCKWELL agrees to defend, indemnify and hold harmless DAVITA, its
affiliates, successors, assigns, directors, officers, agents and employees
("DAVITA Indemnitees") from and against any and all liabilities, demands,
losses, damages, and/or expenses (including costs, expenses, fines, amounts paid
in settlements or judgments, reasonable attorneys' fees, witnesses' fees,
investigation expenses, and, expenses incident thereto) (collectively referred
to as "Damages") that DAVITA Indemnitees may suffer resulting from: (i) any
claim, lawsuit, investigation, proceeding, regulatory action, or other cause of
action (or threats thereof), arising out of the use of any Product or any Mixer
or to the extent arising out of any defect in the design or manufacture of any
Product or any Mixer , including but not limited to claims for property damage,
loss of life, and bodily injury ("Injury"), or (ii) the breach or alleged breach
by ROCKWELL of any warranty, representation or covenant contained in this
Agreement or in materials furnished by ROCKWELL for DAVITA's use. DAVITA agrees
to indemnify, defend, and hold ROCKWELL, its affiliates, successors, assigns,
directors, officers, agents and

                                       5

<PAGE>

employees ("ROCKWELL Indemnitees") harmless from and against any and all Damages
that ROCKWELL Indemnitees may suffer resulting from or arising out of DAVITA's
negligence or misconduct in the "Administration" of any Product to its patients.
For purposes of the foregoing, "Administration" of Product by DAVITA shall mean
the handling by DAVITA of a Product and the actual administration of a Product
to patients by DAVITA, but shall exclude the decision of a physician to
prescribe a Product to a patient. If the Injury is caused by the negligence of
DAVITA and ROCKWELL and/or a physician or other third party, the apportionment
of Damages shall be shared by the parties based upon the comparative degree of
each party's negligence, and each party's own costs, including but not limited
to the costs of defense, attorneys' fees and witnesses' fees and expenses
incident thereto, shall also be apportioned based upon the comparative degree of
each party's negligence.

         b. In the event that any demand or claim is made or suit is commenced
against DAVITA Indemnitees for which ROCKWELL has an indemnity obligation under
this section, written notice of such shall be provided to ROCKWELL, and DAVITA
Indemnitees shall cooperate with ROCKWELL in the defense of the demand, claim or
suit to whatever reasonable extent ROCKWELL requires, and ROCKWELL shall have
the right to compromise such claim to the extent of its own interest and shall
undertake the defense of any such suit. No settlement by ROCKWELL shall be
binding upon DAVITA without DAVITA's prior written consent. Notwithstanding, if
ROCKWELL fails to assume its obligation to defend, DAVITA Indemnitees may do so
to protect their interest and seek reimbursement from ROCKWELL=

         c. In the event that any demand or claim is made or suit is commenced
against ROCKWELL Indemnitees for which DAVITA has an indemnity obligation under
this section, written notice of such shall be provided to DAVITA, and ROCKWELL
Indemnitees shall cooperate with DAVITA in the defense of the demand, claim or
suit to whatever reasonable extent DAVITA requires, and DAVITA shall have the
right to compromise such claim to the extent of its own interest and shall
undertake the defense of any such suit. No settlement by DAVITA shall be binding
upon ROCKWELL without ROCKWELL's prior written consent. Notwithstanding, if
DAVITA fails to assume its obligation to defend, ROCKWELL Indemnitees may do so
to protect their interest and seek reimbursement from DAVITA.

         d. ROCKWELL agrees that it shall secure and maintain in full force and
effect throughout the term of this Agreement (and following termination, to
cover any claims arising from this Agreement) commercial general liability
insurance, which includes contractual liability coverage, product liability and
workers' compensation insurance, with limits acceptable to DAVITA. Any limits on
ROCKWELL'S insurance coverage shall not be construed to create a limit on its
liability with respect to its obligations hereunder. DAVITA shall be named as an
additional insured on vendor's endorsement for product liability insurance. Such
policies shall provide at least thirty (30) days prior written notice to DAVITA
of the cancellation, non-renewal or substantial modification thereof. Rockwell
shall supply certificates of insurance to DAVITA upon request.

                                       6

<PAGE>

         16. Severability. In the event any provision of this Agreement shall be
held to be invalid or unenforceable in any respect, such provision shall be
enforced to the fullest extent permitted by law and the remaining provisions of
this Agreement shall remain in full force and effect. If any such invalid
portion constitutes a material term of this Agreement, the parties shall meet
and in good faith seek to mutually agree to modify this Agreement so as to
retain, if possible, the overall essential terms of this Agreement.

         17. Waiver. The failure to insist upon strict adherence to one or more
or all of the provisions of this Agreement on any one or more occasions, shall
not be construed as a waiver, nor shall such course of action deprive a party of
the right thereafter to require strict compliance with same.

         18. Entire Agreement. This Agreement is the entire agreement between
the parties and supersedes any and all prior agreements and understandings
between the parties, whether oral or written, relating to the subject matter
hereof, including without limitation that certain Preferred Supplier Contract
(East Region) and that certain Preferred Supplier Contract (Midwest Region),
each dated April 14, 2000, and each of which is hereby terminated. No amendments
or modifications of the terms of this Agreement, including any conflicting or
additional terms contained in any purchase order, acknowledgment form, or other
written document submitted by either party, shall be binding on either party
unless reduced to writing and signed by duly authorized representatives of both
parties, or, in the case of waiver, signed by the party against whom such waiver
is construed.

         19. Conflicts. To the extent that any provision of any purchase order,
invoice, or any other document, or the terms of any of ROCKWELL'S or DAVITA'S
general policies, procedures or catalogs, conflict with or materially alter any
term of this Agreement, this Agreement shall govern and control.

         20. Choice of Law. The laws of the State of Delaware, without regard to
principles of conflicts of laws, will govern this Agreement and its subject
matter, construction and the determination of any rights, duties or remedies of
the parties arising out of or relating to this Agreement, its subject matter or
any of the transactions contemplated by this Agreement.

         21. Attorney Fees. In the event of any litigation arising out of this
Agreement, the prevailing party in any such litigation shall be entitled to
recover its reasonable attorneys' fees and costs and expenses of litigation from
the non-prevailing party as shall be approved by a court.

         22. Notices. All notices, requests, demands, and other communications
under this Agreement shall be in writing and shall be deemed to have been duly
given on the date of service if served personally on the party to whom notice is
to be given, or three days after the date of mailing if mailed to the party to
whom notice is to be given, by first class mail, registered or certified,
postage prepaid, and properly addressed as set forth below, or one day following

                                       7

<PAGE>

traceable delivery to a nationally recognized overnight delivery service with
instructions for overnight delivery:

             (a)      To ROCKWELL:     30142 Wixom Road
                                       Wixom, MI 48383
                                       Attn: Robert L. Chioini

             (b)      To DAVITA:       21250 Hawthorne Boulevard
                                       Suite 800
                                       Torrance, CA 90503-5517
                                       Attn:  Kim Brady, Director of Purchasing

                      With a copy to:  21250 Hawthorne Boulevard
                                       Suite 800
                                       Torrance, CA 90503-5517
                                       Attn:  General Counsel

Any party may change its address for purposes of this paragraph by giving the
other party written notice of the new address in the manner set forth above.

         23. Successors and Assigns. This Agreement shall bind and inure to the
benefit of the parties hereto and their respective heirs, executors,
administrators, legal representatives, successors, and assigns.

         24. Force Majeure. All obligations of either party hereto shall be
excused to the extent and for the period of time necessitated by the occurrence
of any act of God, fire, casualty, flood, war, strike, lockout, labor trouble,
failure of public utilities, equipment failure, facility shutdown, injunction,
accident, epidemic, riot, insurrection, destruction of operation or
transportation facilities, inability to procure materials, equipment, personnel
or energy or any other circumstances beyond the reasonable control of the party
asserting it (and not caused by the negligence of the non-performing party),
which prevents or delays the performance by such party of any of its obligations
under this Agreement.

         25. Open Records. To the extent required by ss. 1861(v)(1)(I) of the
Social Security Act, as amended, the parties will allow the U.S. Department of
Health and Human Services, the U.S. Comptroller General and their duly
authorized representatives, access to this Agreement and records necessary to
verify the nature and extent of costs incurred pursuant to it during the Term
and for four years following the last date Products are furnished under it.
Nothing in this paragraph is intended to waive any right either party may have
under applicable law or regulations to retain in confidence information included
in records so requested.

         26. Discounts. Any discounts, rebates, incentives, or other reductions
in price issued by ROCKWELL to DAVITA under this Agreement may constitute a
discount within the

                                       8

<PAGE>

meaning of 42 U.S.C. Section 1320a-7b (b)(3)(A). DAVITA may have an obligation
to properly disclose and appropriately reflect such discount to any state or
federal program that provides cost or charge based reimbursement to DAVITA for
the items to which the discount applies. DAVITA will retain invoices and related
pricing documentation and make them available on request to healthcare program
representatives. In order to assist DAVITA's compliance with any such
obligations, ROCKWELL agrees that it shall provide to DAVITA statements
itemizing any discounts earned and the basis for their calculation, as well as
other information that DAVITA may request that is necessary for it to obtain in
order to comply with any such obligations.

         27. Changes in Reimbursement Systems. The parties acknowledge and agree
that the health care industry in which DAVITA operates is subject to constant
and rapid fluctuation in many areas, including industry growth, consolidation
and changes in reimbursement systems. Accordingly, the parties agree that (i) in
the event of an increase in the number of facilities owned or managed by DAVITA,
which facilities are not already purchasing Products from ROCKWELL; or (ii) in
the event of any significant change in reimbursement systems or in reimbursement
laws, or in the event of the actual enactment of any federal, state or local law
or regulation, or the actual enactment of any reimbursement rule, guideline,
final program memorandum, coverage decision, pricing decision, instruction or
the like by the Centers for Medicare and Medicaid Services or any of Customer's
Medicare fiscal intermediaries, or the actual inclusion of reimbursement systems
that in any manner reforms, modifies, alters, restricts or otherwise affects the
reimbursement available to DAVITA for the Products or its services, the parties
shall meet and confer in good faith within thirty (30) days following DAVITA's
request. Any modification must be mutually agreed to by the parties and set
forth in a written amendment to this Agreement.

         28. Acquired Facilities. If DAVITA acquires any dialysis facility or
facilities during the Term which has a pre-existing agreement with ROCKWELL for
the purchase of any Products ("Acquired Facility"), ROCKWELL agrees that DAVITA
may determine, in its sole and absolute discretion at any time, and regardless
of any provision contained within such pre-existing agreement (including,
without limitation, provisions regarding assignment or termination) , whether to
do any one of the following: (a) include purchases of Products by the Acquired
Facility(ies) within this Agreement; or (b) continue purchases of Products by
the Acquired Facility(ies) within the terms of such pre-existing agreements.

         29. Counterparts. This Agreement may be executed in counterparts both
of which shall be deemed to be originals. Captions are intended for convenience
of reference only.

         30. Relationship. Neither party is in any way the legal representative
or agent of the other nor authorized or empowered to assume any obligation of
any kind, implied or expressed, on behalf of the other party, without the
express written consent of the other. This Agreement shall not constitute,
create or in any way be interpreted as a joint venture or partnership of any
kind.

         31. Joint Preparation. Each party to this Agreement (a) has
participated in the

                                       9

<PAGE>

preparation of this Agreement; (b) has read and understands this Agreement; and
(c) has been represented by counsel of its own choice in the negotiation and
preparation of this Agreement. Each party represents that this Agreement is
executed voluntarily and should not be construed against any party hereto solely
because it drafted all or a portion hereof.

         32. Access. Once DAVITA provides ROCKWELL a written copy of DAVITA'S
general corporate policies, regulations and guidelines regarding access to its
personnel and facilities, ROCKWELL agrees at all times to abide by DAVITA'S
general corporate policies, regulations and guidelines regarding access to its
personnel and facilities. ROCKWELL representatives must coordinate all access
and requests for access through DAVITA'S Corporate Purchasing Department.
ROCKWELL's discussion and marketing of the Products and its educational and
promotional materials shall be in compliance with all applicable laws and
regulations. Access to DAVITA personnel and facilities is contingent upon
DAVITA's approval of ROCKWELL's use in DAVITA facilities of all educational and
promotional materials covering the Products and similar items. ROCKWELL shall
provide to DAVITA'S Corporate Purchasing Department a copy of all such materials
in advance, and agrees that it must obtain permission, in writing, from DAVITA'S
Corporate Purchasing Department prior to ROCKWELL's use of any such materials in
any DAVITA facility. Any subsequent changes in such materials must first be
approved, in writing, by DAVITA'S Corporate Purchasing Department.
Notwithstanding the foregoing, the second sentence of this section 32 shall not
apply to instances when a DAVITA clinic or DAVITA personnel make the initial
contact with ROCKWELL and/or its agents.

         IN WITNESS WHEREOF, the parties hereto have executed this Agreement as
of the date first written above.

ROCKWELL MEDICAL.                           DAVITA INC.
TECHNOLOGIES, INC.

By:  /s/ Robert L. Chioini                  By:   /s/ Guy Seay
     ----------------------                       --------------
Its: President                              Its:  V-P Finance
     ---------                                    ---------------

                                       10

<PAGE>

[ROCKWELL
+ MEDICAL TECHNOLOGIES, INC. LETTERHEAD]

                               DAVITA PRICE QUOTE
                          EXHIBIT A [*            *]

TERRITORY:        [*                                       *]

PRODUCTS:         [*

                                                      *]
<TABLE>
<CAPTION>
------------------------------------------------------------------------------------------
CATALOG #          DESCRIPTION              PACKAGING               UNIT            PRICE
------------------------------------------------------------------------------------------
<S>               <C>                       <C>                     <C>              <C>
[*

                                                                                         *]
-------------------------------------------------------------------------------------------

NOTE:  [*

                                                                                *]

*[*

                         *]

** [*

                                                                                      *]

***[*

                                                                                *]

</TABLE>

                                  Page 1 of 6

<PAGE>

[ROCKWELL
+ MEDICAL TECHNOLOGIES, INC. LETTERHEAD]

                               DAVITA PRICE QUOTE
                      EXHIBIT A [*                          *]

TERRITORY:        [*                               *]

PRODUCTS:         [*

                                                       *]
<TABLE>
<CAPTION>
------------------------------------------------------------------------------------------
CATALOG #          DESCRIPTION              PACKAGING               UNIT            PRICE
------------------------------------------------------------------------------------------
<S>               <C>                       <C>                     <C>              <C>
[*

                                                                                         *]
-------------------------------------------------------------------------------------------

NOTE:  [*

                                                                                      *]

</TABLE>

                                  Page 2 of 6

<PAGE>

[ROCKWELL
+ MEDICAL TECHNOLOGIES, INC. LETTERHEAD]

                               DAVITA PRICE QUOTE
                         EXHIBIT B [*                   *]

TERRITORY:   [*                                            *]

PRODUCTS:    [*                        *]
             [*                           *]

<TABLE>
<CAPTION>
------------------------------------------------------------------------------------------
CATALOG #          DESCRIPTION              PACKAGING               UNIT            PRICE
------------------------------------------------------------------------------------------
<S>               <C>                       <C>                     <C>              <C>
[*

                                                                                         *]
-------------------------------------------------------------------------------------------

NOTE:  [*

                                                                                      *]

</TABLE>

                                  Page 3 of 6

<PAGE>

[ROCKWELL
+ MEDICAL TECHNOLOGIES, INC. LETTERHEAD]

                               DAVITA PRICE QUOTE
                         EXHIBIT B [*                   *]

TERRITORY:  [*                          *]

PRODUCTS:   [*                                    *]
            [*                                        *]

<TABLE>
<CAPTION>
------------------------------------------------------------------------------------------
CATALOG #          DESCRIPTION              PACKAGING               UNIT            PRICE
------------------------------------------------------------------------------------------
<S>               <C>                       <C>                     <C>              <C>
[*

                                                                                         *]
-------------------------------------------------------------------------------------------

NOTE:  [*

                                                                                      *]

</TABLE>

                                  Page 4 of 6

<PAGE>

[ROCKWELL
+ MEDICAL TECHNOLOGIES, INC. LETTERHEAD]

                               DAVITA PRICE QUOTE
                          ATTACHMENT TO EXHIBIT'S A & B

TERRITORY:   [*
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                                  Page 5 of 6

<PAGE>

[ROCKWELL
+ MEDICAL TECHNOLOGIES, INC. LETTERHEAD]

                                    EXHIBIT C
                      DAVITA SHIPPING & ORDERING GUIDELINES
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                                  Page 6 of 6<PAGE>
                                                                   EXHIBIT 10.20

                       $2,500,000.00 REVOLVING CREDIT LOAN

                                 AMENDMENT NO. 1
                                       TO
                           LOAN AND SECURITY AGREEMENT

                      ORIGINALLY DATED AS OF MARCH 28, 2001

                                  BY AND AMONG

                       ROCKWELL MEDICAL TECHNOLOGIES, INC.
                                       AND
                          ROCKWELL TRANSPORTATION, INC.

                                       AND

                         HELLER HEALTHCARE FINANCE, INC.

                          AMENDED AS OF MARCH 28, 2003
<PAGE>
                 AMENDMENT NO. 1 TO LOAN AND SECURITY AGREEMENT

         THIS AMENDMENT NO. 1 TO LOAN AND SECURITY AGREEMENT (this "Amendment")
is made as of this 28th day of March, 2003, by and among ROCKWELL MEDICAL
TECHNOLOGIES, INC. a Michigan corporation, and ROCKWELL TRANSPORTATION, INC., a
Michigan corporation (collectively, "Borrower"), and HELLER HEALTHCARE FINANCE,
INC., a Delaware corporation ("Lender").

                                    RECITALS

         A. Pursuant to that certain Loan and Security Agreement dated March 28,
2001 (as previously amended, and as amended hereby and as further amended,
modified and restated from time to time, collectively, the "Loan Agreement") by
and among Borrower and Lender, the parties have established certain financing
arrangements that allow Borrower to borrow funds from Lender in accordance with
the terms and conditions set forth in the Loan Agreement.

         B. The parties now desire to amend the Loan Agreement to extend the
Term of the Loan from March 28, 2003 to March 29, 2005 and to make certain other
changes to the Loan Agreement, all as more specifically described below.

         NOW, THEREFORE, in consideration of the premises set forth above, the
terms and conditions contained in this Amendment, and other good and valuable
consideration, the receipt and sufficiency of which are hereby acknowledged,
Lender and Borrower have agreed to the following amendments to the Loan
Agreement:

         1. DEFINITIONS. Capitalized terms used but not defined in this
Amendment shall have the meanings that are set forth in the Loan Agreement.

         2. AMENDMENTS TO LOAN AGREEMENT.

                  2.1. SECTION 2.1(a) -- MAXIMUM LOAN AMOUNT. Section 2.1(a) of
the Loan Agreement is hereby deleted in its entirety and amended and restated as
follows:

                  "(a) The maximum aggregate principal amount of credit extended
                  by Lender to Borrower under this Agreement (the "Loan") that
                  will be outstanding at any time is Two Million Five Hundred
                  Thousand and No/100 Dollars ($2,500,000.00) (the "Maximum Loan
                  Amount")."

                  2.2. SECTION 2.8(a) - TERM. Section 2.8(a) of the Loan
Agreement is hereby deleted in its entirety and amended and restated as follows:

                  "(a) Subject to Lender's right to cease making Revolving
                  Credit Loans to Borrower upon or during the continuance of any
                  Event of Default, this Agreement shall be in effect for a
                  period of two (2) years from the Closing
<PAGE>
                  Date, unless terminated as provided in this Section 2.8 (the
                  "Term"), and this Agreement shall be renewed for one-year
                  periods thereafter upon the mutual written agreement of the
                  parties."

                  2.3. SECTION 6.23 -- MINIMUM NET WORTH. Section 6.23 of the
Loan Agreement is hereby deleted in its entirety and amended and restated as
follows:

                  "SECTION 6.23. NET WORTH. Borrower will not at any time allow
                  its net worth, as computed in accordance with GAAP, to fall
                  below $750,000."

         3. CONFIRMATION OF REPRESENTATION, WARRANTIES AND COVENANTS. Borrower
hereby (a) confirms that all of the representations and warranties set forth in
Article IV of the Loan Agreement are true and correct with respect to Borrower
as of the date hereof, and Borrower covenants to perform its obligations under
the Loan Agreement, and (b) specifically represents and warrants to Lender that
it has good and marketable title to all of its respective Collateral, free and
clear of any lien or security interest in favor of any other person or entity
except for Permitted Liens and the Mechanics Lien described below.

         4. ENFORCEABILITY; EFFECTIVE DATE. This Amendment constitutes the
legal, valid and binding obligation of Borrower, and is enforceable against each
such Borrower in accordance with its terms. This Amendment shall be effective
upon execution and delivery to Lender of the following documents, all of which
must be in a form reasonably acceptable to Lender, and all of which shall
constitute conditions precedent to the effectiveness of this Amendment:

                  (a) Two (2) originals of this Amendment No. 1 to Loan and
         Security Agreement executed by Borrower and the Certificate of
         Validity; and

                  (b) A Secretary's Certificate certifying that Borrower's
         Articles of Incorporation and Bylaws have not been amended as of the
         date of closing, and including a unanimous consent of all members of
         the board of directors authorizing the amendments set forth herein and
         the transactions contemplated hereby; and

                  (c) Any other deliverables or items requested by Lender, in
         its reasonable discretion.

         5. POST CLOSING OBLIGATIONS. On or before June 30, 2003, Borrower shall
have paid any outstanding sales taxes due and owing to any applicable
Governmental Authority, and shall have used commercially reasonable efforts to
reimburse any sales taxes owed to any Person required to be reimbursed pursuant
to applicable laws (the "Tax Payments"). Failure by the Borrower to comply with
this Section 5 shall, upon Lender's written notice to Borrower, constitute an
Event of Default under the Loan Agreement. Until such time as the Tax Payments
and the mechanic's lien filed with the county clerk's office of Oakland County,
Michigan at Liber 23661 Pg. 759 on September 18, 2001 (the "Mechanics Lien") are
satisfied as described herein, Lender and Borrower hereby acknowledge and agree
that Lender shall maintain an adequate reserve on the Borrowing Base Certificate
in an amount that it deems necessary in its commercially reasonable discretion,
which as of the date hereof, is an amount equal to $19,500 for the Tax Payments
and $22,040 for the Mechanics Lien.

                                       2
<PAGE>
         6. FEES AND COSTS. In consideration for Lender's increase in the
Maximum Loan Amount and the extension of the Term and the other amendments set
forth herein, and without limiting any other fee to which Lender is entitled
under the Loan Agreement, Borrower hereby agrees to pay to Lender a fee equal to
Twenty-Five Thousand and No/100 Dollars ($25,000). In addition, Borrower shall
be responsible for the payment of all reasonable fees of Lender's in-house
counsel incurred in connection with the preparation of this Amendment and any
related documents. Borrower hereby authorizes Lender to deduct all of such fees
set forth in this Section 6 from the proceeds of the next Revolving Credit
Loan(s).

         7. RELEASE. Borrower hereby fully, finally, and absolutely and forever
releases and discharges Lender and its present and former directors,
shareholders, officers, employees, agents, representatives, successors and
assigns, and their separate and respective heirs, personal representatives,
successors and assigns, from any and all actions, causes of action, claims,
debts, damages, demands, liabilities, obligations, and suits, of whatever kind
or nature, in law or equity of Borrower, whether now known or unknown to
Borrower, and whether contingent or matured (collectively, "Claims"): (a) in
respect of the Loan Agreement, the Loan Documents, or the actions or omissions
of Lender in respect of the Loan Agreement and the Loan Documents; and (b)
arising from events occurring prior to the date of this Amendment. The foregoing
release and discharge shall, automatically and without further action of the
Borrower, be deemed renewed as of the date of each advance of Loan proceeds with
respect to all Claims in respect of the Loan Agreement, the Loan Documents, or
the actions or omissions of Lender in respect of the Loan Agreement and the Loan
Documents and arising from events occurring prior to the date of such advance.

         8. REFERENCE TO THE EFFECT ON THE LOAN AGREEMENT.

                  (a) Upon the effectiveness of this Amendment, each reference
in the Loan Agreement to "this Agreement," "hereunder," "hereof," "herein" or
words of similar import shall mean and be a reference to the Loan Agreement as
amended by this Amendment.

                  (b) Except as specifically amended above, the Loan Agreement,
and all other Loan Documents, shall remain in full force and effect, and are
hereby ratified and confirmed.

                  (c) The execution, delivery and effectiveness of this
Amendment shall not, except as expressly provided in this Amendment, operate as
a waiver of any right, power or remedy of Lender, nor constitute a waiver of any
provision of the Loan Agreement, or any other documents, instruments and
agreements executed or delivered in connection with the Loan Agreement.

         9. GOVERNING LAW. This Amendment shall be governed by and construed in
accordance with the laws of the State of Maryland.

         10. HEADINGS. Section headings in this Amendment are included for
convenience of reference only and shall not constitute a part of this Amendment
for any other purpose.

         11. COUNTERPARTS. This Amendment may be executed in counterparts, and
all such counterparts taken together shall be deemed to constitute one and the
same instrument.

                                       3
<PAGE>
         IN WITNESS WHEREOF, the parties have caused this Amendment to be
executed as of the date first written above.

WITNESS/ATTEST:
                                    LENDER:

                                    HELLER HEALTHCARE FINANCE, INC.,
                                    a Delaware corporation

By: /s/ Lisa Lenderman              By: /s/ Hanes Whiteley
    --------------------                -------------------
Name:  Lisa Lenderman               Name:  Hanes Whiteley
Title: Senior Counsel               Title: Vice President

                                    BORROWER:

                                    ROCKWELL MEDICAL TECHNOLOGIES, INC.,
                                    a Michigan corporation

By: /s/Robert L. Chioini            By: /s/ Thomas E. Klema
    --------------------                -------------------
Name:  Robert L. Chioini            Name:   Thomas E. Klema
Title: Chairman and CEO             Title:  Vice President and Secretary

                                    ROCKWELL TRANSPORTATION, INC.,
                                    a Michigan corporation

By: /s/Robert L. Chioini            By: /s/ Thomas E. Klema
    --------------------                -------------------
Name:  Robert L. Chioini            Name:   Thomas E. Klema
Title: Chairman and CEO             Title:  Vice President and Secretary

                                       4

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