Document:

Diligent Board Member Services Stock
Purchase Plan

 

The Company has adopted, effective July
26, 2012, the following stock purchase plan (the “Plan”):

 

		1.	Employees and directors of the Company are eligible to purchase up to US$15,000 worth of shares
of the Company’s common stock once per quarter. A director participating in the plan in any quarter shall do so by directing
the Company to apply director’s fees payable to him or her that quarter against the purchase of the Company’s stock
under the Plan.

 

		2.	The date of purchase of the shares of Company stock under the Plan will be the eleventh (11th)
business day following announcement to NZX of the Quarterly Update report by the Company (the “Purchase Date”). The
Company will notify all employees and directors in writing each quarter of the Purchase Date for purchase of shares of Company
stock under the Plan.

 

		3.	The purchase price will be determined by computing the Volume Weighted Average Price of the Company’s
stock on the NZX over the five (5) trading days immediately preceding the Purchase Date. The resultant price in New Zealand dollars
will be converted to US dollars on the Purchase Date.

 

		4.	The maximum aggregate dollar amount of shares which can be purchased by directors and employees
under the Plan in any quarter shall not exceed $500,000.

 

		5.	Employees and directors must notify the Company Treasurer in writing of their desire to purchase
stock by no later than the business day prior to the Purchase Date. On the Purchase Date, the Company will notify each purchaser
in writing of the purchase price per share (as determined in accordance with paragraph 3 above) and the amount owed for the shares
being purchased by them.

 

		6.	Payment of the purchase price will be due from the employee or director by no later than the close
of business on the business day following the Purchase Date.

 

		7.	Upon receipt of the purchase price from the participating employee or director, the shares will
be registered with Link Market Services, the Company’s registrar, in the purchaser’s name.

 

		8.	The Board of Directors can amend or revoke the Plan at any time.

 

		9.	The Stock Issuance Committee of the Board will monitor the administration of the Plan and authorize
the issuance of shares of the Company’s stock to each employee and director purchasing shares under the Plan.Portions herein identified by
[*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of
1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange
Commission.

 

ASSET PURCHASE AGREEMENT

  

This Asset Purchase
Agreement (the "Agreement") is made and entered into as of the 8th day of November, 2012 by and between SYNTHETIC
BIOLOGICS, INC, a Nevada corporation having its principal place of business at 617 Detroit Street, Ann Arbor, Michigan 48104 (“Synthetic”
or “Buyer”), and PREV ABR LLC, a Maryland limited liability company having its principal place of business at 7272
Wisconsin Avenue, Suite 300, Bethesda, Maryland 20814 ("Seller").

 

WITNESSETH:

 

WHEREAS, Seller owns
and desires to sell and assign to Buyer certain assets and related intellectual property (collectively, the “Assets”)
as specifically defined in Section 1.1 of this Agreement and Buyer desires to purchase and acquire such Assets from Seller and,
thereafter, to use, market, license, sublicense, develop, maintain, collect and otherwise deal with the Assets without restriction.

 

NOW, THEREFORE, in
consideration of the respective representations and warranties hereinafter set forth and of the mutual covenants and agreements
contained herein, the parties hereto agree as follows:

 

ARTICLE I

 

DEFINITIONS

 

As used herein, the following terms shall
have the following meanings:

 

1.1           "Assets"
shall mean the Seller’s CDAD program including any and all of the following assets of the Seller,
including any and all rights and benefits constituting and relating to the Seller's β-lactamase technology and all other biomedical
or pharmaceutical technologies of the Seller and all β-lactamase products detained and/or developed with the aforementioned
technologies, including without limitation the lead P1A, P2A and P3A-based products in preclinical and clinical phases (the
"Program") and all tangible and intangible intellectual property and know how exclusively related thereto including the
following:

 

    	1

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

(a)          all
methods and data sets , and all technical documentation pertaining to the Program, including any specifications, flow charts, diagrams,
lab results and any and all notes, all inventor notebook pages specific to the Program, plans and other documentation describing
problems, future directions or other matters exclusively related to the Program;

 

(b)          (i)
all patents, patent rights, copyrights, trademarks, trademark rights, tradenames, tradename rights and patent, copyright or trademark
applications exclusively respecting the Program and related intellectual property; (ii) all reissues, reexaminations, extensions,
continuations, continuations-in-part, continuing prosecution applications, requests for continuing examinations, divisions and
registrations of any item in any of the foregoing categories; (iii) foreign counterparts of any of the foregoing; (iv) all patent
and patent applications claiming any right of priority to or through the patent applications of the patents listed on Exhibit
B hereto; (v) all rights to apply in all countries of the world for patents certificates of invention, utility models, industrial
design protections, design patent protections, or other governmental grants or issuances of any type related to any item in any
of the foregoing categories (i) through (v), including, without limitation, under the Paris Convention for the Protection of Industrial
Property, the International Patent Cooperation Treaty, or any other convention, treaty, agreement, or understanding; (vi) all invention,
invention disclosures and discoveries described in any of the patents listed on Exhibit B hereto that are included in any
claim in such patents, and/or are subject matter capable of being reduced to a patent claim in a reissue or reexamination proceeding
brought on any of the patents; (vii) all causes of action (whether known or unknown, or whether currently pending, filed or otherwise)
and other enforcement rights under, or on account of, any of the patents and/or rights (as described on Exhibit B); (viii)
all rights to collect royalties and other payments under or on account of the patents or any item in any categories (i) through
(vii); (ix) all ideas, know-how, trade secrets, inventions, invention disclosures, discoveries, technology, designs and any other
proprietary rights which Seller owns, in each case with respect to any of the above, pertaining exclusively to the Program (collectively,
"Proprietary Rights"); and (x) a list of upcoming filings, all US Patent and Trademark Office and other patentability
assessments;

 

    	2

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

(c)          all
cGMP and non-cGMP material and master call banks of P1A, P2A and P3A and all other tangible assets related thereto;

 

(d)          any
and all U.S. and international investigational new drug applications (IND) and pre-INDs of Seller;

 

(e)          information
and know-how related to research, development, manufacture and/or business (commercial/marketing), used or held for use in connection
with the Program;

 

(f)          any
and all health and regulatory registrations, approvals and/or applications and related documentation for the Program;

 

(g)          any
and all drugs, formulations and user devices, applications, and safety data;

 

(h)          all
other information, documentation and goodwill relating to the Program;

 

(i)          all
regulatory files (paper and electronic) or so-called regulatory files and records of communications and filings with any and all
regulatory authorities in both paper and electronic form; and

 

(j)          the
Assets shall be maintained by the Seller’s office and warehouse located at Wisconsin Avenue, Bethesda, MD and working and
mater cell banks, cGMP and non-cGMP drug substance and drug product wherever located pending the Closing or until earlier relocated
by operation of this Agreement. The Seller shall cooperate with and allow the Buyer to remove the Assets during normal business
hours during such period.

 

    	3

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

1.2           “Buyer”
shall refer to Synthetic Biologics, Inc., however Synthetic Biologics, Inc shall have the right, in its sole discretion, to determine
that the Assets shall be acquired by one of its wholly owned subsidiaries and in such case Buyer shall refer to such wholly owned
subsidiary.

 

ARTICLE II

 

SALE AND PURCHASE OF ASSETS

 

2.1           Sale
and Purchase. Subject to the terms and conditions contained herein, Seller hereby sells, transfers, assigns, conveys and delivers
to Buyer, and Buyer hereby purchases and accepts from Seller, all of Seller's right, title and interest in and to the Assets,
free and clear of any liens, pledges, security interests, claims or encumbrances of any kind, other than liens for taxes not yet
due and payable. Upon the Closing, Buyer shall have the sole responsibility and authority to prosecute any pending patent application
included in the Assets or related thereto.

 

2.2           Limitation
on Assumption. Except for the Assumed Liabilities (as defined in Section 2.3 below), Buyer shall not assume, pay or discharge
or in any respect be liable for any liability, obligation, commitment or expense of Seller arising in connection with the Assets
or otherwise. The liabilities for which Buyer shall not be liable include, without limitation, any liability (actual or contingent),
loss, commitment, obligation or expense of Seller:

 

(a)          incident
to, or arising out of, the negotiation and preparation of, or performance under this Agreement by Seller, including, without limitation,
costs incurred in connection with the assignment of the Assets;

 

    	4

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

(b)          incident
to, or arising out of, any claims, actions, suits, proceedings, liabilities, fines, penalties, deficiencies or judgments existing
on the date hereof or arising at any time thereafter as a result of or in connection with the conduct of the business of Seller,
including, without limitation, the ownership or use of the Assets by Seller and Seller's conduct of its business up to and including
the Closing Date;

 

(c)          incident
to, or arising out of, any tax liabilities (or penalties or interest thereon), domestic or foreign (including any which may arise
as a result of the sale of the Assets as contemplated by this Agreement), of Seller on account of this Agreement or the operations
of Seller up to and including the Closing Date; or

 

(d)          incident
to or arising out of any liability incurred prior to the date hereof with respect to the patents listed on Exhibit B hereto,
including annuity, maintenance, extension, legal and other similar fees.

 

2.3           Assumption
of Liabilities; Limitation on Seller's Liability. Buyer (or Synthetic and Buyer jointly and severally, if Buyer is a wholly
owned subsidiary of Synthetic) shall assume, be responsible for and pay, perform and discharge when due all liabilities, obligations,
commitments or expenses arising after the Closing from the ownership, possession and/or use of the Assets by Buyer, its affiliates,
successors or assigns (collectively, the "Assumed Liabilities"). In addition, Buyer (or Synthetic and Buyer jointly and
severally, if Buyer is a wholly owned subsidiary of Synthetic ) shall assume, be responsible for and pay, perform and discharge
when due the following liabilities, obligations, commitments or expenses arising after the execution of this Agreement and prior
to the Closing; provided, however that neither the Buyer nor any affiliate, parent or subsidiary thereof shall have no such obligation
if this Agreement is terminated prior to Closing:

 

    	5

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

(a)          incident
to, or arising out of, any claims, actions, suits, proceedings, liabilities, fines, penalties, deficiencies or judgments as a result
of Buyer’s conduct of its business or Buyer’s ownership and use of the Assets after the execution of this Agreement;

 

(b)          incident
to, or arising out of, any tax liabilities (or penalties or interest thereon), domestic or foreign, of Buyer or the operations
of Buyer or Buyer’s ownership and use of the Assets after the Closing, specifically excluding any tax liabilities associated
with the transactions contemplated by this Agreement; or

 

(c)          incident
to or arising out of any liability incurred after the date hereof with respect to the patents listed on Exhibit B hereto,
including annuity, maintenance, extension, legal and other similar fees with respect to the filings in the jurisdictions set forth
on Exhibit B.

 

To the extent Buyer is
(or Synthetic and Buyer are, if Buyer is a wholly owned subsidiary of Synthetic) responsible for any such costs or expenses pursuant
to this Section 2.3 and the expenses are advanced by the Seller between execution of this Agreement and Closing, at the Closing,
Buyer (or Synthetic and Buyer, if Buyer is a wholly owned subsidiary of Synthetic ) and shall reimburse Seller for such costs and
expenses, with such reimbursement being a condition to Seller’s obligation to close. If Buyer does not close the transaction
contemplated herein or the transaction is terminated, neither Buyer nor any affiliate, parent or subsidiary thereof shall have
any obligation to Seller under this Section 2.3 and its only obligation to Seller shall be under Article XII of this Agreement.

 

2.4           Consideration.
The consideration payable by Buyer (or Synthetic and Buyer, if Buyer is a wholly owned subsidiary of Synthetic) for the Assets
to be sold to Buyer as provided herein shall be as follows:

 

(a)          A
cash payment payable by wire transfer of immediately available funds to an account designated by Seller in writing in the amount
of Two Hundred Thirty Five Thousand Dollars ($235,000) payable as follows: (i) One Hundred Thousand Dollars ($100,000) payable
on the date of the execution of this Agreement; and (ii) One Hundred Thirty Five Thousand Dollars ($135,000) payable on the Closing
Date.

 

    	6

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

(b)          On
the Closing Date, Six Hundred Twenty Five Thousand (625,000) shares of Synthetic’s common stock (the “Shares”),
of which Two Hundred Fifty Thousand (250,000) Shares shall be issued to Seller and Three Hundred Seventy Five Thousand (375,000)
shares shall be held in escrow by Gracin & Marlow, LLP, as escrow agent, for a period of 180 days in accordance with the terms
of the Escrow Agreement annexed hereto as Exhibit C (the “Escrow Agreement”); and

 

(c)          The
fees set forth on Exhibit D annexed hereto upon the attainment of the milestones set forth on Exhibit D. Buyer and
Seller shall promptly make such payments upon reaching such milestones.         

 

2.5           Allocation
of the Purchase Price. For tax purposes, the parties agree that all of the consideration for the Assets shall be allocated
to the purchase of the Program and the other Assets in accordance with Section 1060 of the Internal Revenue Code of 1986, as amended,
and the regulations promulgated thereunder (and any similar provision of domestic or foreign law, as appropriate) as set forth
on Exhibit E.

 

ARTICLE III

 

CLOSING; CONDITIONS TO CLOSING; DELIVERIES

 

3.1           Closing.
The closing of this transaction (the "Closing") shall be held on the date which is five days after all conditions to
Closing set forth in Section 3.2 have been met, unless this Agreement has been earlier terminated in accordance with the provisions
of Article XI (the "Closing Date") at such time and place upon which the parties shall agree.

 

    	7

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

3.2           Conditions
to Buyer’s Obligation. Buyer’s obligation hereunder to purchase and pay for the Assets is subject to the satisfaction,
on or before the Closing, of the following conditions, any of which may be waived, in whole or in part, by Buyer in its sole discretion:

 

(a)          Representations
and Warranties Correct; Performance. The representations and warranties of Seller contained in this Agreement (including the
Exhibits hereto) shall be true, complete and accurate in all material respects (except that such representations and warranties
which are qualified as to materiality shall be accurate and complete in all respects) as of the date hereof and the Closing Date,
and Seller shall have delivered to Buyer a certificate, dated as of the date hereof and the Closing Date, to such effect signed
by its President. Seller shall have duly and properly performed, complied with and observed in all material respects each of its
covenants, agreements and obligations contained in this Agreement to be performed, complied with and observed on or before the
Closing Date, and Seller shall have delivered to Buyer a certificate, dated the Closing Date, to such effect signed by its Managing
Member.

 

(b)          Purchase
Permitted by Applicable Laws. The purchase of and payment for the Assets to be purchased by Buyer hereunder shall not be prohibited
by any applicable law or governmental regulation.

 

(c)          Proceedings;
Receipt of Documents. All corporate and other proceedings taken or required to be taken by Seller in connection with the transactions
contemplated hereby and all documents incident thereto shall have been taken and shall be reasonably satisfactory in form and substance
to Buyer, and Buyer shall have received all such information and such counterpart originals or certified or other copies of such
documents as Buyer may reasonably request.

 

(d)          Delivery
of Documents. Seller shall have delivered, or caused to be delivered, to Buyer the following:

 

    	8

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

(i)          on
the date hereof and the Closing Date, a certificate of the Managing Member of Seller, certifying resolutions of the Managing Member
of Seller authorizing the transactions contemplated herein and the incumbency of the Managing Member of Seller executing any document
or instrument delivered in connection with such transactions;

 

(ii)         on
the date hereof and the Closing Date, a limited liability company good standing certificate of Seller from the jurisdiction in
which Seller is organized dated as of a recent date;

 

(iii)        on
the Closing Date documentation evidencing the assignment of all patents from the inventors of the Program to Seller and the related
filing with the US Patent and Trademark Office and all files and documents reasonably necessary to establish Seller’s ownership
of the Assets;

 

(iv)        on
the Closing Date documentation evidencing the payment of all patent prosecution fees owed on such date and all annuity, maintenance,
extension and the like fees on the patents that comprise the Assets through the date of Closing;

 

(v)         on
the Closing Date a duly executed Assignment and Bill of Sale with respect to the Assets, in substantially the form of Exhibit
F annexed hereto and with respect to all of the Patents listed on Exhibit B hereto an executed and notarized Patent
Assignment in the form of Exhibit H annexed hereto for filing by the Buyer with the United States Patent and Trademark Office;

 

(vi)        on
the Closing Date, evidence of ownership of the Patents listed on Exhibit B;

 

(vii)       on
the Closing Date a duly executed copy of the Escrow Agreement; 

 

    	9

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

(viii)      on
the Closing Date transfer of possession of any tangible property related to
the Program which is in Seller’s possession or readily available to Seller; and 

 

(ix)         all
other consents, agreements, schedules, documents and exhibits required by this Agreement to be delivered by Seller at or before
the Closing.

 

(e)          No
Adverse Decision. There shall be no action, suit, investigation or proceeding pending or threatened by or before any court,
arbitrator or administrative or governmental body which seeks to restrain, enjoin, prevent the consummation of or otherwise affect
the transactions contemplated by this Agreement or questions the validity or legality of any such transactions or seeks to recover
damages or to obtain other relief in connection with any such transactions.

 

(f)          Approvals
and Consents. Seller shall have duly obtained all authorizations, consents, rulings, approvals, licenses, franchises, permits
and certificates, or exemptions therefrom, by or of all governmental authorities and non-governmental administrative or regulatory
agencies having jurisdiction over the parties hereto, this Agreement, the Assets or the transactions contemplated hereby, including,
without limitation, all third parties pursuant to existing agreements or instruments by which Seller may be bound, which are required
for the execution, delivery and performance of this Agreement and the consummation of the transactions contemplated hereby, at
no material cost or other material adverse consequence to Buyer, and all thereof shall be in full force and effect at the time
of Closing.

 

(g)          Employees
and Consultants. Seller shall have delivered to Buyer agreements signed by each of its employees, if any, and consultants involved
in any manner with development efforts related to the Program (i) waiving any and all rights to, and conveying to Seller, any and
all right, title and interest in, all proprietary products, patents, copyrights, trademarks (or applications in respect of any
thereof) and any and all other intellectual property comprising any part of the Assets or developed or conceived by such employee
or consultant while so employed; and (ii) agreeing that each such employee or consultant will not disclose any confidential information
and documents related to the Assets in perpetuity, except as may be permitted under such agreements for exclusions typically taken
for information already released to the public and other similar exclusions.

 

    	10

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

(h)          Due
Diligence. Buyer shall have completed the due diligence on the Assets and the Seller, the completion of and the satisfactoriness
of the scientific and financial due diligence in the sole discretion of the Buyer.

 

(i)          Audit.
If Buyer shall deem it necessary, Seller shall have permitted a PCAOB registered independent accounting firm retained by Buyer,
at Buyer’s expense, to review the books and records of Seller and such firm shall have either completed an audit of Buyer’s
books and records or concluded that Buyer’s books and records are auditable.

 

3.3           Conditions
to the Obligation of Seller. The obligation of Seller to consummate the transactions contemplated hereby is subject to the
fulfillment of the following conditions on or prior to the Closing Date, any of which may be waived, in whole or in part, by Seller
in its sole discretion:

 

(a)          Representations
and Warranties Correct; Performance. The representations and warranties of Buyer in this Agreement shall be true, complete
and accurate in all material respects (except that such representations and warranties which are qualified as to materiality shall
be accurate and complete in all respects) when made and on and as of the date hereof and the Closing Date and Buyer shall have
delivered to Seller a certificate, dated the date hereof and the Closing Date, certifying to such matters and signed by its President.
Buyer shall have duly and properly performed, complied with and observed in all material respects each of its covenants, agreements
and obligations contained in this Agreement to be performed, complied with and observed on or before the Closing Date. Buyer shall
have delivered to Seller a certificate, dated the Closing Date, certifying to such matters and signed by its President.

 

    	11

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

(b)          Purchase
Permitted by Applicable Laws. The purchase of and payment for the Assets shall not be prohibited by any applicable law or governmental
regulation.

 

(c)          No
Adverse Decision. There shall be no action, suit, investigation or proceeding pending or threatened by or before any court,
arbitrator or administrative or governmental body which seeks to restrain, enjoin or prevent the consummation of or otherwise affect
the transactions contemplated by this Agreement or questions the validity or legality of any such transactions or seeks to recover
damages or to obtain other relief in connection with any such transactions.

 

(d)          Delivery
of Documents. Buyer shall have delivered, or caused to be delivered, to Seller the following:

 

(i)          on
the date hereof and the Closing Date, a certificate of an appropriate officer of Buyer (or a certificate of both Synthetic and
Buyer, if Buyer is a wholly owned subsidiary of Synthetic), certifying resolutions of the Board of Directors of Buyer authorizing
the transactions contemplated herein and the incumbency of officers of Buyer executing any document or instrument delivered in
connection with such transactions;

 

(ii)         on
the date hereof evidence that Buyer has been duly incorporated in Nevada and on the Closing Date, a corporate good standing certificate
of Buyer from the jurisdiction in which Buyer is incorporated dated as of a recent date;

 

(iii)        the
cash consideration set forth in Section 2.4(a) on the dates specified therein;

 

(iv)        on
the Closing Date, certificates evidencing the Shares, of which Three Hundred Seventy Five Thousand (375,000) shall be delivered
to the escrow agent in accordance with the terms of the Escrow Agreement;

 

(v)         on
the Closing Date a duly executed copy of the Escrow Agreement;

 

    	12

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

(vi)        on
the Closing Date documentation evidencing approval of the NYSE MKT, LLC of the issuance of the Shares;

 

(vii)       on
the Closing Date payment of any audit fees incurred by Buyer from a PCAOB registered and certified accounting firm retained by
Buyer in connection with this transaction;

 

(viii)      all
other consents, agreements, schedules, documents and exhibits required by this Agreement to be delivered by Buyer at or before
the Closing; and

 

(ix)         reimbursement
of costs and expenses for which Buyer (or Buyer and Synthetic, if Buyer is a wholly owned subsidiary of Synthetic) are responsible
under Section 2.3.

 

ARTICLE IV

 

SELLER'S REPRESENTATIONS AND WARRANTIES

 

Seller represents and warrants to, and agrees
with, Buyer as follows as of the date hereof:

 

4.1           Organization
and Good Standing. Seller is a limited liability company duly organized, validly existing and in good standing under the laws
of the State of Maryland.         

 

    	13

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

4.2           Limited
Liability Company Authority. Seller has full authority to execute and to perform this Agreement in accordance with its terms;
the execution and delivery of this Agreement and the consummation of the transactions contemplated hereby does not and will not
result in a breach, violation or default or give rise to an event which, with the giving of notice or after the passage of time,
or both, would result in a breach, violation or default of (i) any of the terms or provisions of Seller's Articles of Organization
or Operating Agreement; or (ii) of any indenture, agreement, judgment, decree or other instrument or restriction to which Seller
is a party or by which Seller or any of the Assets may be bound or affected, except in the case of clause (ii) where such breach,
violation or default would not have a material adverse effect on the assets or the Program (“Material Adverse Effect”);
the execution and delivery of this Agreement has been and, as of the Closing Date, the consummation of the transactions contemplated
hereby will have been, duly authorized by all requisite limited liability company action on the part of Seller and, as of the date
hereof, no further authorization or approval, whether of the stockholders or directors of Seller or governmental bodies or otherwise
will be necessary in order to enable Seller to enter into and perform the same; and, assuming the due authorization, execution
and delivery of this Agreement by Buyer, this Agreement constitutes a valid and binding obligation of Seller enforceable against
Seller in accordance with its terms, subject to applicable bankruptcy, insolvency, reorganization, moratorium, fraudulent transfer
and other similar laws affecting creditors’ rights generally from time to time in effect and to general principles of equity
(including concepts of materiality, reasonableness, good faith and fair dealing) regardless of whether considered in a proceeding
in equity or at law.

 

4.3           Title
to Assets.

 

(a)          Seller
has good and marketable title to all of the Assets, including, without limitation, the Program and the Proprietary Rights;

 

(b)          None
of such Assets, or the use thereof is subject to any easements or restrictions or to any mortgages, liens, pledges, charges, security
interests, encumbrances or encroachments, or to any rights of others of any kind of nature whatsoever. There are no agreements
or arrangements between Seller and any third person which have any effect upon Seller's title to or other rights respecting the
Assets;

 

(c)          Seller
has made available to Buyer all files owned or controlled by Seller relating to the ownership, prosecution or issuance of the Proprietary
Rights being assigned other than those files retained by its patent and/or trademark counsel, in which case Seller has made its
counsel available to Buyer; and

 

    	14

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

(d)          Seller
is unaware of any divisional, continuation, continuation in part, reissue or re-examination applications, or any patents issued
therefrom, that rely on the patents set forth on Exhibit B hereto.

 

4.4           Intellectual
Property.

 

(a)          Seller
owns all right, title and interest by assignment and possesses a valid and enforceable right to use, all of the Proprietary Rights
used in the Program, and no claim to the contrary by any other person to the rights of Seller with respect to the foregoing is
pending or, to Seller’s knowledge, threatened and Seller does not have any reason to believe that Seller will not be able
to properly record the assignment of the patents and patent applications that are included in the Assets with the appropriate U.S.
and international patent offices in the name of Buyer at Closing. 

 

(b)          There
is no unauthorized use, disclosure, infringement or misappropriation of Seller’s Proprietary Rights by any third party, other
than any such unauthorized use, disclosure, infringement or misappropriation that would not have a Material Adverse Effect.

 

(c)          Exhibit
B attached hereto lists all patents and patent applications and all registered trademarks, service marks and copyrights included
as part of the Assets ("Registered Proprietary Rights"). Except as set forth on Exhibit B, Seller owns exclusively
all such Registered Proprietary Rights.

 

(d)          Seller
has no present or known future obligation or requirement to compensate any person with respect to the Assets, whether by the payment
of royalties or not, or whether by reason of the ownership, use, license, lease, sale or any commercial use or any disposition
whatsoever of the Program or the Proprietary Rights; 

 

    	15

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

(e)          None
of the present or former employees of Seller own directly or indirectly, or has any other right or interest in, in whole or in
part, the Program, or the Proprietary Rights;

 

(f)          Seller
has not granted any rights or interest in the Assets to any third party;

 

(g)          All
issued patents listed on Exhibit B hereto are subsisting and in full force and effect. Neither the execution of this Agreement
nor the assignment of the patents and patent rights listed on Exhibit B hereto will result in any loss or impairment of
the right, title and interest in and to such patents. None of the patents listed on Exhibit B hereto is currently involved
in any reexamination reissue, interference, opposition or similar proceeding, and no such proceedings are pending or threatened;

 

(h)          All
licenses necessary for the present conduct of Seller's business related to the Program and its making, using, licensing and selling
of the Program and products related thereto have been obtained and are listed in Exhibit B hereto; and

 

(i)          To
the best knowledge of Seller, the pending patent applications listed in Exhibit B are currently pending at the United States Patent
and Trademark Office and International PTO and all required filings relating thereto have been made.

 

4.5           Compliance
With Law. Seller is not in violation in any material respect of any laws, governmental orders, rules or regulations to which
the Assets or Seller's business related to the Assets are subject.

 

4.6           Agreements.
There are no material contracts, instruments, commitments or agreements relating to the Assets, whether oral or written, including
any license or sublicense agreements, presently in effect to which Seller is a party or to which Seller or any of its properties
is subject, including, without limitation, the following:

 

(a)          any
plan or contract or arrangement, oral or written, relating to the Assets providing for employment or consulting services, bonuses,
royalties, commissions, pensions, stock purchase or stock option or other stock rights, deferred compensation, retirement or severance
payments, profit sharing, or the like;

 

    	16

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

(b)          any
instrument or arrangement relating to the Assets evidencing or relating in any way to (i) indebtedness for borrowed money by way
of direct loan, purchase money obligation, conditional sale, lease purchase arrangement, guarantee or otherwise; (ii) liens, encumbrances
or security interests (other than liens for taxes not yet due and payable); (iii) guaranties or indemnification; or (iv) investments
in any person;

 

(c)          any
contract relating to the Assets containing provisions limiting the freedom of Seller to engage in any business or compete in any
line of business or in any geographic area or with any person;

 

(d)          any
license, sublicense, lease or sublease agreement relating to the Assets, whether as licensor, sublicensor, licensee, sublicensee,
lessor, sublessor, lessee, sublessee or otherwise, or any agreements relating to the Assets with dealers, vendors, customers, suppliers,
sales representatives, any governmental entity, fund or university, or any agents, marketing representatives, brokers or distributors;
or

 

(e)          any
joint venture contract or arrangement or other agreement relating to the Assets involving a sharing of profits or expenses, or
any joint or other technology development, cooperation or exchange contract or arrangement.

 

4.7           Litigation.
There are no actions, suits, proceedings or investigations (including any purportedly on behalf of Seller) relating to the Assets
pending or, to the knowledge of Seller, threatened against or affecting the Assets or Seller's business related to the Assets whether
at law or in equity or admiralty or before or by any governmental department, commission, board, agency, court or instrumentality,
domestic or foreign; including any patent enforcement actions or any other intellectual property prosecution actions.

 

    	17

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

4.8           Liabilities.
As of the Closing Date, there will be no outstanding liabilities with respect to the Assets, other than liens for taxes not yet
due and payable, and all intellectual property prosecution fees owed through the date hereof, if any have been paid in full. As
of the Closing Date, all filing, maintenance and annuity, extensions and like fees required to be paid or accrued as of the date
hereto with respect to all of the issued patents listed on Exhibit B hereto will have been paid by Seller (for the avoidance
of doubt, such timely payment includes payment of any maintenance fees for which the fee is payable even if the surcharge date
or final deadline for such fee would be in the future). With respect to the jurisdictions set forth on Exhibit B, the anticipated
filing, maintenance and annuity, extensions and like fees required that will be required to be paid with respect to all of the
issued patents listed on Exhibit B hereto within the next thirty (30) days is accurate.

 

4.9           Brokers.
There has been no broker or finder involved in any manner in the negotiations leading up to the execution of this Agreement or
the consummation of any transactions contemplated hereby and Seller agrees to indemnify Buyer against and hold Buyer harmless from
any claim made by any party for a broker's or finder's fee or other similar payment based upon any agreements, arrangements or
understanding made by Seller.

 

    	18

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

4.10         Accredited
Investor. The Seller is acquiring the Shares for its own account for investment only and not with a view towards the public
sale or distribution thereof and not with a view to or for sale in connection with any distribution thereof. The Seller was not
formed for the purpose of investing in the Shares. Each member of the Seller is (i) an “accredited investor” as that
term is defined in Rule 501 of the General Rules and Regulations under the Securities Act by reason of Rule 501(a)(3); (ii) experienced
in making investments of the kind described in this Agreement and the related documents; (iii) able, by reason of the business
and financial experience of its officers and professional advisors (who are not affiliated with or compensated in any way by the
Buyer or any of its affiliates or selling agents), to protect its own interests in connection with the transactions described in
this Agreement, and the related documents, and (iv) able to afford the entire loss of its investment in the Shares. The Seller
understands that the Shares are being offered and issued to it in reliance on specific exemptions from the registration requirements
of United States federal and state securities laws and that the Buyer is relying upon the truth and accuracy of, and the Seller’s
compliance with, the representations, warranties, agreements, acknowledgements and understandings of the Seller set forth herein
in order to determine the availability of such exemptions and the eligibility of the Seller to acquire the Shares;

 

4.11         SEC
Filings. The Seller and its advisors, if any, have been furnished with all materials relating to the business, finances and
operations of the Buyer and materials relating to the offer and sale of the Shares which have been requested by the Seller. The
Seller and its advisors, if any, have been afforded the opportunity to ask questions of the Buyer and have received complete and
satisfactory answers to any such inquiries. Without limiting the generality of the foregoing, the Seller has also had the opportunity
to obtain and to review the Buyer’s Annual Report on Form 10-K/A for the year ended December 31, 2011, its Quarterly Report
on Form 10-Q for each of the quarters ended March 31, 2012 and June 30, 2012 filed with the Securities and Exchange Commission
(the “SEC Documents”). Neither the Buyer nor any other person on its behalf has made any representations to the Seller
except as contained in the Buyer’s SEC Documents or in this Agreement and in making the decision to purchase the Shares,
the Seller has not relied on any representation or information other than those which Seller has independently investigated and
verified.

 

4.12         Risks.
The Seller understands that its investment in the Shares involves a high degree of risk and that Seller can bear the economic risk
of the purchase of the Shares, including total loss of his investment. Seller has adequate means of providing for current needs
and has no need for liquidity in the investment. Reference is made to the factors discussed in the “Risk Factor” section
of Buyer’s SEC documents.

 

    	19

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

4.13         Grants.
The Seller has no knowledge that any pending NIH grants or any other grants that it has shall be terminated or are subject to termination
or non-fulfillment either prior to or as a result of this Agreement. Seller shall provide all reasonable cooperation to assist
Buyer in finalizing any NIH pending grants associated with the Program. 

 

4.14         Exclusive
Representations and Warranties. Other than the representations and warranties set forth in this Agreement (including the Exhibits
hereto), Seller is not making any other representation or warranty, express or implied, with respect to the Assets or the Program.

 

ARTICLE V

 

REPRESENTATIONS AND WARRANTIES OF BUYER

 

Buyer (or Synthetic and Buyer jointly and
severally, if Buyer is a wholly owned subsidiary of Synthetic) represents and warrants to, and agrees with, Seller as follows:

 

5.1           Organization
and Good Standing. It is a corporation duly organized, validly existing and in good standing under the laws of the State of
Nevada.

 

5.2           Corporate
Authority. It has full authority to execute and to perform this Agreement in accordance with its terms; the execution and delivery
of this Agreement and the consummation of the transactions contemplated hereby does not and will not result in a breach, violation
or default or give rise to an event which, with the giving of notice or after the passage of time, or both, would result in a breach,
violation or default of any of the terms or provisions of its Certificate of Incorporation, By-Laws or of any indenture, agreement,
judgment, decree or other instrument or restriction to which it is a party or by which it may be bound or affected; the execution
and delivery of this Agreement and the consummation of the transactions contemplated hereby have been duly authorized by all requisite
corporate action on the part of it and no further authorization or approval, whether of its stockholders or directors or governmental
bodies or otherwise, is necessary in order to enable it to enter into and perform the same (other than NYSE MKT approval); and
this Agreement constitutes a valid and binding obligation enforceable against it in accordance with its terms.

 

    	20

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

5.3           Capitalization.
Synthetic has provided to Seller a schedule that sets forth its authorized and issued capital stock, options, warrants and convertible
securities. Other than as set forth on such schedule, Synthetic does not have outstanding any options to purchase, or any rights
or warrants to subscribe for, or any securities or obligations convertible into or any contracts or commitments to issue or sell
common stock or any such warrants, convertible securities or obligations.

 

5.4           Validity
of Shares. The Shares have been duly authorized and upon receipt of the approval of the NYSE MKT LLC, will be validly issued
(including, without limitation, in compliance with applicable federal and state securities laws) and when issued as provided herein
will be fully paid and non-assessable. Such Shares are free and clear of all mortgages, pledges, liens, security interests, encumbrances,
conditional sales agreements, charges, claims and restrictions of any kind and nature whatsoever, and the Seller will obtain good
and valid title to such Shares free and clear of all mortgages, pledges, liens, security interests, encumbrances, conditional sales
agreements, charges, claims and restrictions of any kind and nature whatsoever.

 

5.5           SEC
Documents. Notwithstanding the foregoing, it represents and warrants that each of the SEC Documents presents fairly Synthetic’s
financial condition as of the date of such filing and there has been no material adverse change in its financial condition from
the date of the SEC Documents.

 

    	21

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

5.5           Brokers.
There has been no broker or finder involved in any manner in the negotiations leading up to the execution of this Agreement or
the consummation of any transactions contemplated hereby and Buyer agrees to indemnify Seller against and hold Seller harmless
from any claim made by any party for a broker's or finder's fee or other similar payment based upon any agreements, arrangements
or understanding made by Buyer.

 

ARTICLE VI

 

COVENANTS OF SELLER

 

6.1           Delivery
of Assets. Simultaneously herewith, Seller shall deliver to Buyer all materials and other information Seller has which comprise
or exclusively relate to the Assets, including all existing, proposed or expired agreements exclusively respecting the Program
and all regulatory filings related to the Assets.

 

6.2           Further
Assurances. Seller agrees that, at any time after the date hereof, upon the request of Buyer, it will do, execute, acknowledge
and deliver, or will cause to be done, executed, acknowledged and delivered, all such further acknowledgments, deeds, assignments,
bills of sale, transfers, conveyances, instruments, consents and assurances as may reasonably be required for the better assigning,
transferring, granting, conveying, assuring and confirming to Buyer, its successors and assigns, the Assets to be transferred to
Buyer as provided herein. Seller agrees to cause its officers, managing member and management to reasonably cooperate with Buyer
and Buyer’s representatives and agents to make themselves available to the extent reasonably necessary to complete the transfer
of the Assets and the filing of any assignments with the United States Patent and Trademark Office and any foreign similar office.
In the event that a party hereto becomes aware of any existing patent or pending patent application that is covered by the definition
of Proprietary Rights but which is not currently listed on Exhibit B hereto, such patent or patent application shall automatically
be covered by the definition of Proprietary Rights and shall be deemed to constitute a Proprietary Right of Buyer. Seller, at no
cost or expense to Seller, shall take all action reasonably requested by Buyer to effectuate the assignment to Buyer of any grants
or pending grants and to effectuate the obtainment and possession of any tangible material related to the Program.

 

    	22

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

6.3           Information
Rights. Buyer shall provide Seller with any rights to non-public financial information, financial statements, inspection rights,
and other information rights specifically provided to any other common shareholders.

 

6.4           Conduct
of the Business Pending the Closing. From and after the date hereof until the Closing Date:

 

(a)          Seller
shall carry on its business relating to the Assets and the Program in the ordinary course consistent with past practice, including,
without limitation, the prosecution of any pending patent applications, and the payment of any maintenance fees upon the earliest
date due on any patents, included in the Assets or related thereto, shall preserve its ownership in the Assets, and shall not engage
in any transaction or activity relating to the Assets, enter into any agreement, or make any commitment relating to the Assets;

 

(b)          Seller
shall preserve and keep intact its business organization relating to the Assets;

 

(c)          Except
as permitted by this Agreement, without the prior written consent of Buyer, Seller will not:

 

(i)          permit
or allow any of the Assets to be subjected to any mortgages, liens, pledges, charges, security interests, encumbrances or encroachments,
or to any rights of others of any kind of nature whatsoever;

 

    	23

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

(ii)         take
any actions to modify, terminate or amend any of the documents comprising the Assets;

 

(iii)        engage
in the sale, license, assignment, transfer, conveyance, lease, mortgage, pledge or other disposition of the Assets;

 

(iv)        incur
any liability relating to the Assets other than the fees set forth in Section 2.3 which Seller has agreed to pay and Buyer has
(or Synthetic and Buyer, if Buyer is a wholly owned subsidiary of Synthetic have) agreed to reimburse; or

 

(v)         agree,
whether in writing or otherwise, to do any of the foregoing.

 

(d)          Seller
shall not do any act or omit to do any act, which will cause a breach of any contract or commitment of Seller or which would cause
the breach of any representation, warranty or covenant made hereunder.

 

ARTICLE VII

 

CONDUCT OF BUSINESS OF BUYER PENDING
FILING OF AN IND

 

Between the Closing Date and the filing
of an IND:

 

7.1           Regular
Course of Business. Buyer shall carry on its business relating to the Assets and the Program in the ordinary course consistent
with past practice, including, without limitation, the prosecution of any pending patent applications, and the payment of any maintenance
fees upon the earliest date due on any patents, included in the Assets or related thereto, shall preserve its ownership in the
Assets, and shall not engage in any transaction or activity relating to the Assets, enter into any sale, license, pledge or encumbrance
of the Assets. To the extent that Buyer deems it advisable to sublicense ex-U.S. rights prior to the filing on an IND to further
the development of Assets in international regulatory jurisdictions wherein any such sublicense will be subject to the terms of
this Agreement, Seller agrees to not unreasonably withhold consent for such sublicense without consideration.

 

    	24

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

7.2           Organization.
Buyer shall preserve and keep intact its business organization relating to the Assets and shall use reasonable efforts to continue
to make all payments and filings necessary to maintain all patent filings in jurisdictions in which Seller currently has made filings.

 

7.3           Certain
Changes. Except as permitted by this Agreement, without the prior written consent of Seller, Buyer will not:

 

(a)          permit
or allow any of the Assets to be subjected to any mortgages, liens, pledges, charges, security interests, encumbrances or encroachments,
or to any rights of others of any kind of nature whatsoever;

 

(b)          take
any actions to modify, terminate or amend any of the documents comprising the Assets;

 

(c)          engage
in the sale, license, assignment, transfer, conveyance, lease, mortgage, pledge or other disposition of the Assets;

 

(d)          incur
any liability relating to the Assets; or

 

(e)          agree,
whether in writing or otherwise, to do any of the foregoing.

 

7.4           No
Default. Buyer shall not do any act or omit to do any act, which will cause a breach of any contract or commitment of Buyer
or which would cause the breach of any representation, warranty or covenant made hereunder.

 

ARTICLE VIII

 

SURVIVAL; INDEMNIFICATION

 

8.1           Survival
of Representations and Warranties. The representations and warranties set forth in Article IV shall survive the Closing Date.
All covenants and agreements that by their terms apply, or that are to be performed in whole or in part at or after the Closing,
shall survive from and after the Closing Date for the period provided in such covenant or agreement, if any, or otherwise until
fully performed. The provisions of this Section 8.1 shall survive the termination of this Agreement.

 

    	25

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

8.2           Seller
Indemnity Against Claims. Seller hereby agrees to indemnify and hold Buyer harmless from and against any and all liabilities,
losses, damages, claims, costs and reasonable expenses of any nature, including attorney fees and costs ("Loss") to the
extent such Loss arises from or in connection with the following:

 

(a)          any
material breach by Seller of any representation or warranty contained in this Agreement;

 

(b)          any
material breach by Seller of any of its covenants contained in this Agreement; and

 

(c)          any
excluded liability.

 

The indemnity granted
by Seller in this paragraph shall not apply with respect to any Loss arising out of any breach by Buyer of its representations,
warranties and agreements set forth herein.

 

8.3           Buyer
Indemnity Against Claims. Buyer hereby agrees to indemnify and hold Seller harmless from and against any and all Losses to
the extent such Losses arise from or in connection with the following:

 

(a)          any
material breach by Buyer of any representation or warranty contained in this Agreement;

 

(b)          any
material breach by Buyer of any of its covenants contained in this Agreement; and

 

(c)          any
Assumed Liability.

 

    	26

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

The indemnity granted
by Buyer in this paragraph shall not apply with respect to any Loss arising out of any breach by Seller of its representations,
warranties and agreements set forth herein.

 

8.4           Notice
of Claim, Assumption of Defense and Settlement of Claims.

 

(a)          A
party seeking indemnification (an "Indemnified Party") under this Article VIII shall promptly give notice (an "Indemnification
Notice") in accordance with Section 13.1 hereof to the indemnifying party (the "Indemnifying Party") after the Indemnified
Party shall have knowledge of any demands, claims, actions or causes of action (singly, a "Claim" and hereinafter referred
to collectively, as "Claims") which might give rise to a Claim by the Indemnified Party against the Indemnifying Party,
stating the nature and basis of said Claim and the amount thereof, to the extent known. A failure to give notice hereunder shall
not relieve the Indemnifying Party from any obligation hereunder except to the extent such failure to give notice shall materially
and adversely affect the Indemnifying Party’s ability to defend the Claim. After the delivery of an Indemnification Notice
certifying that the Indemnified Party has incurred or had asserted against it any Losses for which indemnity may be sought in accordance
with the terms of this Article VIII, the Indemnified Party shall deliver to the Indemnifying Party all information and documentation
reasonably requested by the Indemnifying Party with respect to such Loss.

 

(b)          With
respect to any third party Claims made subsequent to the Closing Date, the following procedures shall be observed:

 

(i)          Promptly
after delivery of an Indemnification Notice in respect of a Claim, the Indemnifying Party may elect, by written notice to the Indemnified
Party, to undertake the defense thereof with counsel reasonably satisfactory to the Indemnified Party and at the sole cost and
expense of the Indemnifying Party.

 

    	27

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

(ii)         Failure
by the Indemnifying Party to notify the Indemnified Party of its election to defend any such action within twenty (20) days after
notice thereof shall have been given, shall be deemed a waiver by the Indemnifying Party of its right to defend and settle such
action. If the Indemnifying Party assumes the defense of any such Claim, its obligations hereunder as to such Claim shall be limited
to taking all steps reasonably necessary in the defense or settlement of such Claim and to holding the Indemnified Party harmless
from and against any and all Losses awarded in any such proceeding or arising out of any settlement approved by the Indemnifying
Party or any judgment in connection with such Claim.

 

(iii)        The
Indemnifying Party shall not, in the defense of any such Claim, consent to the entry of any judgment (except with the prior written
consent of the Indemnified Party, which consent shall not be unreasonably withheld or delayed) or enter into any settlement (except
with the prior written consent of the Indemnified Party, which consent shall not be unreasonably withheld or delayed ) which does
not include as an unconditional term thereof the giving by the claimant or the plaintiff to the Indemnified Party of a complete
release from all liability in respect of such Claim.

 

(iv)        If
the Indemnifying Party does not assume the defense of a Claim, the Indemnified Party shall diligently defend such claim, and the
Indemnifying Party shall promptly reimburse the Indemnified Party for all reasonable expenses, legal or otherwise, incurred by
the Indemnified Party in connection with the defense against and settlement of such Claim, net of any tax benefits realized by
Buyer arising from such expenses, as and when the same shall be incurred by the Indemnified Party; provided, however, that the
Indemnified Party provides an undertaking to repay such expenses to the Indemnifying Party if it is ultimately and finally determined
by a court of competent jurisdiction and all rights of appeal have lapsed that such Indemnified Party is not entitled to indemnification
under this Article VIII or under applicable law or otherwise. The Indemnified Party shall not admit any liability with respect
to, or settle, compromise or discharge, such third party Claim without the Indemnifying Party’s prior written consent, which
will not be unreasonably withheld or delayed. In the event the Indemnified Party assumes the defense of the Claim, the Indemnified
Party will keep the Indemnifying Party reasonably informed of the progress of any such defense, compromise or settlement.

 

    	28

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

(v)         The
Indemnifying Party shall reimburse the Indemnified Party for all Losses actually incurred by the Indemnified Party as ultimately
and finally determined by a court of competent jurisdiction, net of any tax benefits realized by Buyer arising from such Losses.

 

(c)          With
respect to any Claims other than third party Claims made subsequent to the Closing Date, the following procedures shall be observed:

 

(i)          The
Indemnifying Party shall have thirty (30) days following receipt of any Indemnification Notice pursuant hereto to (A) agree to
the amount or method of determination of Losses set forth in the Indemnification Notice to pay such amount to the Indemnified Party
in immediately available funds, or (B) provide the Indemnified Party with notice that they disagree with the amount or method of
determination of Losses set forth in the Indemnification Notice, and the parties shall thereafter attempt to resolve the disagreement
by negotiation in good faith; provided that if the parties are unable to reach agreement within sixty (60) days of such notice,
the dispute shall be submitted for final adjudication to the applicable court sitting in the State of Michigan in accordance with
Section 13.3. The Indemnifying Party shall reimburse the Indemnified Party for all Losses actually incurred by the Indemnified
Party as ultimately and finally determined by a court of competent jurisdiction, net of any tax benefits realized by Buyer arising
from such Losses.

 

    	29

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

8.5           Limitations;
Exclusive Remedy; Effect of Knowledge of Breach.

 

(a)          Buyer
and Seller acknowledge and agree that the indemnification provided in this Article VIII shall not be the sole remedy for Losses
related to or arising at law, under any statute or in equity, or otherwise out of this Agreement or the transactions contemplated
hereby (other than claims of or causes of action arising from a finding of actual fraud or willful misconduct); and

 

(b)          Without
limiting the effect of any other limitation contained in this Article VIII, no representation or warranty of Seller, on the one
hand, or Buyer, on the other hand, shall be deemed to be or to have been breached if the other party establishes by documentary
evidence that the counterparty had knowledge, on or prior to the date of this Agreement of the breach of such representation or
warranty, or of any facts or circumstances rendering such representation or warranty inaccurate.

 

8.6           Right
to Set Off. Notwithstanding anything to the contrary set forth in this Agreement or any Exhibit hereto, with respect to any
amounts due and payable to Buyer under this Article VIII, Buyer shall have the right to set off the amount of such Loss against
any amounts due to Seller hereunder or otherwise.

 

    	30

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

ARTICLE IX

 

CONFIDENTIALITY AND NON-COMPETITION

 

9.1           Confidentiality.
From after the Closing Date and for a period of five (5) years thereafter or earlier termination of this Agreement, Seller shall
retain in strictest confidence, and shall not use for its benefit or for the benefit of others all confidential information comprising
or related to the Assets, including, without limitation, the technology, know-how, trade secrets, transferred hereby to Buyer,
product development techniques or plans, or technical processes, designs and design projects exclusively respecting the Program;
provided, however, that Seller may use or disclose any such confidential information to fulfill any of its obligations hereunder.
Notwithstanding the foregoing, Seller shall not be prohibited from using or disclosing any such confidential information which:
(i) enters the public domain or is publicly available, provided that such public knowledge was not the result of any breach of
this Agreement attributable to the Seller, or (ii) is required to be disclosed by such Seller pursuant to applicable law or court
order, in which case, the Seller shall give written notice to Buyer prior to such disclosure so that Buyer may seek a protective
order or other appropriate remedy, and the Seller will reasonably cooperate with Buyer in any proceeding to obtain a protective
order or other remedy. From after the execution of this Agreement until the Closing Date or earlier termination of this Agreement,
each party shall retain in strictest confidence, and shall not use for its benefit or for the benefit of others all confidential
information comprising or related to the Assets other than in order to fulfill its obligations under this Agreement, including,
without limitation, the technology, know-how, trade secrets, transferred hereby to Buyer, product development techniques or plans,
or technical processes, designs and design projects exclusively respecting the Program.  Notwithstanding the foregoing, neither
party shall be prohibited from using or disclosing any such confidential information which: (i) enters the public domain or is
publicly available, provided that such public knowledge was not the result of any breach of this Agreement attributable to the
receiving party; or (ii) is required to be disclosed by the receiving party pursuant to applicable law, rule or regulation applicable
to such party or court order, in which case, the receiving party shall give written notice to the disclosing party prior to such
disclosure so that the disclosing party may seek a protective order or other appropriate remedy, and the receiving party will reasonably
cooperate with the disclosing party in any proceeding to obtain a protective order or other remedy.  The Buyer’s obligations
under the third sentence of this Section 9.1 shall continue for a period of five (5) years after execution of this Agreement if
this Agreement is terminated prior to Closing.

 

    	31

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

9.2           Non-Competition.

 

(a)          For
a period ending on the earlier of termination of this Agreement or five (5) years from and after the Closing Date, Seller shall
not, directly or indirectly engage in a business or enterprise (either as proprietor, partner, employee, agent, consultant, or
controlling stockholder) in the development or marketing of any program or intellectual property focused on Clostridium Difficile
Associated Diarrhea (CDAD) (a "competing business").

 

(b)          The
provisions of this Section 9.2 shall not prevent Seller from directly or indirectly investing its assets in securities of any corporation,
or otherwise acquiring an equity interest in any enterprise, equity securities of which are publicly owned and traded, provided
that such investments or interests shall not result in (i) Seller directly or indirectly owning beneficially, in the aggregate,
five percent (5%) or more of the equity securities of any enterprise engaged in a competing business or (ii) Seller being able
to control or actively participate in the policy decisions of such competing business.

 

(c)          It
is the desire and intent of the parties that the provisions of this Section 9.2 shall be enforced to the fullest extent permissible
under the laws and public policies applied in each jurisdiction in which enforcement is sought. If any particular provision or
portion of this Section 9.2 shall be adjudicated to be invalid or unenforceable in any jurisdiction, this Section 9.2 shall be
deemed amended to delete therefrom such provision or portion adjudicated to be invalid or unenforceable, such amendment to apply
only with respect to the operation of this paragraph in the particular jurisdiction in which such adjudication is made. If there
is a breach or threatened breach of the provisions of this Section 9.2, Buyer shall be entitled to an injunction restraining the
Seller from such breach without the obligation of posting a bond. Nothing herein shall be construed as prohibiting Buyer from pursuing
any other remedies for such breach or threatened breach.

 

    	32

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(d)          Seller
declares that the foregoing territorial and time limitations are reasonable and properly required for the adequate protection of
the business of Buyer. In the event any such territorial or time limitation is deemed to be unreasonable by a court of competent
jurisdiction, Seller agrees to the reduction of either said territorial or time limitation to such area or period which said court
shall have deemed reasonable.

 

(e)          The
existence of any claim or cause of action by Seller against Buyer or any subsidiary other than under this Agreement shall not constitute
a defense to the enforcement by Buyer or any subsidiary of the foregoing restrictive covenants, but such claim or cause of action
shall be litigated separately.

 

(f)          The
undertakings and covenants of Seller contained in this Section 9.2 are an integral part of the transactions set forth in this Agreement
and the consideration paid by Buyer pursuant to this Agreement shall be consideration not only for the Assets but also for such
undertakings and covenants.

 

ARTICLE X

 

SPECIAL COVENANTS

 

10.1         Cooperation.
The parties shall cooperate with each other fully with respect to actions reasonably required or requested to be undertaken with
respect to tax audits, administrative actions or proceedings, litigation and any other matters that may occur after the date hereof,
and each party shall maintain and make available to the other party upon reasonable request all corporate, tax and other records
required or requested in connection with such matters. Seller shall also reasonably assist Buyer, at no cost to Seller, in asserting
claims under the assigned patents including obtaining from the inventors prompt production of documents and facts, giving of testimony,
execution of petitions and other assistance necessary for filing patent applications, infringement and enforcement or other actions
or proceedings.

 

    	33

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

10.2         Publicity.
Each party hereto agrees that it shall not disclose any of the terms and conditions of this Agreement or the transactions contemplated
hereby and that no publicity release or announcement concerning this Agreement or the transactions contemplated hereby shall be
issued, in each case without the advance written approval of the other party; provided, however that each party shall be entitled
to disclose the terms and conditions of this Agreement and the transactions contemplated hereby if it is required to be disclosed
by it pursuant to applicable law, rule or regulation or court order. Notwithstanding the foregoing, each party may disclose the
terms of this Agreement to their accountants and attorneys solely for use in connection with the preparation of tax returns or
in complying with the terms of this Agreement.

 

    	34

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

ARTICLE XI

 

CLAWBACK RIGHTS/UNWIND

 

11.1         Rights
of the Seller To Force An Unwind. If on or prior to the date that is (i) thirty (30) months after the date of the execution
of this Agreement, the Buyer has not initiated toxicology studies in a non-rodent model, or (ii) thirty-six (36) months of the
date of execution of this Agreement, the Buyer has not filed an IND under the Program and such failure to file is not related to
and not due to any action or inaction of the Seller or a breach of the representations or warranties or covenants of the Seller
contained in this Agreement, then, as an exclusive remedy, Seller may elect, in its sole discretion, to have the Assets reverted
back to Seller and Buyer shall no longer have any right, title or interest in the Assets. Notwithstanding the foregoing, Buyer
shall have the right to extend the foregoing thirty (30) and thirty-six (36) month periods by an additional twelve (12) months
by advancing to Seller the first milestone payment of ***** on or before (a) thirty (30) months of the date of execution of this
Agreement if Buyer has not initiated toxicology studies in a non-rodent model under the Program, or (b) thirty-six (36) months
of the date of execution of this Agreement if Buyer has not filed an IND under the Program, time being of the essence. In addition,
if a change of control of Buyer (or Buyer or Synthetic, if Buyer is a wholly owned subsidiary of Synthetic) shall occur and thereafter
Buyer fails to use reasonable efforts to pursue development of the Program, then, as an exclusive remedy, Seller may elect, in
its sole discretion, to have the Assets reverted back to Seller and Buyer shall no longer have any right, title or interest in
the Assets. For purposes of this Section 11.1 a change in control shall mean (a) any person (excluding current beneficial owners
of five percent (5%) or more of Synthetic’s outstanding common stock) becomes the beneficial owner (as term is defined in
the Securities Exchange Act of 1934) directly or indirectly, of securities representing more than fifty percent (50%) of the total
voting power of Buyer’s (or Buyer’s or Synthetic’s, if Buyer is a wholly owned subsidiary of Synthetic) shares;
or (b) within a twelve (12) month period, there is a change in the composition of the Board of Directors as a result of which fewer
than a majority of the then directors are Incumbent Directors.  Incumbent Directors shall mean directors who are either
directors of the Seller at least twelve (12) months prior to such change in composition or are elected by the Board of Directors
with the affirmative vote of a majority of the Incumbent Directors at the time of election. At any time after the thirty (30) month
or thirty-six (36) month periods in this Section 11.1, Seller may request from Buyer documentation that Buyer has initiated toxicology
studies in a non-rodent model under the Program or that Buyer has filed an IND under the Program. Within fifteen (15) days after
such a request from Seller, Buyer shall provide such documentation to Seller. If pursuant to this Section 11.1 the Assets revert
to Seller, then Section 9.1 shall apply to the Confidential Information obtained by Buyer from Seller (exclusive of any improvements
or enhancements made to the Assets by Buyer) as though Buyer was the Seller and Seller was the Buyer for purposes of Section 9.1.

 

    	35

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11.2         Procedure
upon Unwind. In the event of an unwind pursuant to Section 11.1 hereof, written notice thereof shall forthwith be given to
the other parties hereto and the Buyer shall immediately execute and deliver to Buyer, a Bill of Sale and Assignment, in substantially
the same form as annexed hereto as Exhibit F (other than to reflect Buyer as the assignor and Seller as the assignee), and
a Recordable Patent Assignment, in substantially the form annexed hereto as Exhibit H (other than to reflect Buyer as the
assignor and Seller as the assignee), assigning all of Buyer’s right, title and interest in the Assets and intellectual property
originally conveyed hereunder, to Seller, and from and after the date of delivery of the written notice, Buyer’s interest
in the such assets and intellectual property rights shall terminate. Such assignment shall be in at least all of the jurisdictions
set forth on Exhibit B. If the transactions contemplated by this Agreement is unwound Buyer will redeliver to Seller all
documents, work papers and other material of the Seller relating to the transactions contemplated hereby that the Seller has delivered
to the Buyer whether so obtained before or after the execution hereof.

 

ARTICLE
XII

 

TERMINATION

 

12.1         Right
To Terminate. This Agreement may be terminated at any time prior to the Closing:

 

(a)          by
mutual written agreement of Seller and Buyer;

 

(b)          by
the Seller if the Closing shall not have been consummated on or before the thirtieth day after the execution of this Agreement;
provided, however, that the right to terminate this Agreement under this Section 12.1(b) shall not be available to
the Seller if the failure to fulfill any obligation under this Agreement by Seller has been the cause of, or resulted in, the failure
of the Closing to occur on or before such date; or

 

(c)          by
the Buyer at any time.

 

    	36

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

The party
desiring to terminate this Agreement pursuant to Section 12.1 shall give notice of such termination to the other party.

 

12.2         Effect
of Termination.  

 

(a)          If
this Agreement is terminated as permitted by Section 12.1(c), such termination shall be without liability of either party to the
other party to this Agreement except that Buyer shall be entitled to the prompt reimbursement by Seller of one half (Fifty Thousand
Dollars) of the cash payment made to Seller under Section 2.4 of this Agreement and any fees paid by Buyer pursuant to Section
2.3 of this Agreement; provided further that if such termination shall result from the failure of Seller to fulfill
its obligations under this Agreement then Buyer shall be entitled to the prompt reimbursement by Seller of the entire One Hundred
Thousand Dollars ($100,000) paid to Seller under Section 2.4 of this Agreement in addition to reimbursement of any fees paid by
Buyer pursuant to Section 2.3 of this Agreement. 

 

ARTICLE XIII

 

GENERAL PROVISIONS

 

13.1         Notices.
All notices, requests, demands and other communications hereunder shall be in writing and shall be deemed to have been duly given
or made as follows: (i) if sent by registered or certified mail in the United States return receipt requested, upon receipt; (ii)
if sent by nationally recognized overnight air courier, one (1) business day after mailing; (iii) if sent by facsimile transmission
or electronic mail, with a copy mailed on the same day in the manner provided in clauses (i) or (ii) of this Section 13.1, when
transmitted and receipt is confirmed; and (iv) if otherwise actually personally delivered, when delivered, in each case if addressed:

 

    	37

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

(a)          in
the case of Synthetic or Buyer to:

 

Synthetic Biologics, Inc.

617 Detroit Avenue, Suite 100

Ann Arbor, Michigan 48104

Facsimile: (734) 332-7878

Attention: Jeffrey L. Riley

Email Address: jriley@syntheticbiologics.com

 

with a copy (which shall not constitute
notice) to:

 

Gracin & Marlow, LLP

405 Lexington Avenue, 26thFloor

New York, New York 10174

Attention: Leslie Marlow, Esq.

Facsimile: (212) 208-4657

Email Address: lmarlow@gracinmarlow.com

 

(b)          in
the case of Seller to:

 

Prev ABR LLC

7272 Wisconsin Avenue, Suite 300

Bethesda, Maryland 20814

Attention: R Michael Floyd

Facsimile: (301) 986 4811

Email Address:mfloyd@lsmgrp.com

 

or to such other address or to such other person as Buyer or
Seller shall have last designated by written notice given as herein provided.

 

13.2         Modification.
This Agreement and the Exhibits and Schedules annexed hereto contain the entire agreement between the parties hereto and there
are no agreements, warranties or representations with respect to the subject matter hereof which are not set forth herein. All
prior negotiations, agreements and understandings are superseded hereby. This Agreement may not be modified or amended except by
an instrument in writing duly signed by or on behalf of the parties hereto.

 

    	38

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

13.3         Governing
Law. This Agreement shall be governed by and construed and enforced in accordance with the laws of the State of Michigan applicable
to agreements made and to be performed entirely within the State. Seller hereby irrevocably consents to the jurisdiction of any
Michigan State or Federal court located in Michigan over any action or proceeding arising out of any dispute between Seller and
Buyer, and irrevocably agrees, in this regard, not to commence any action or proceeding arising out of any dispute
between Seller and Buyer in any other jurisdiction. Seller further irrevocably consents to the service of process in any such action
or proceeding by the mailing of a copy of such process to it at the address set forth above.

 

13.4         Binding
Effect; Assignment. This Agreement shall be binding upon the parties and inure to the benefit of the successors and assigns
of the respective parties hereto. Neither party may assign its rights or obligations under this Agreement without the prior written
consent of the other party; provided, however, that Buyer may assign its rights and obligations under this Agreement, without the
prior written consent of the other party, to an affiliate or to a successor of the relevant portion of the assigning party’s
business by reason of merger, sale of all or substantially all of its assets or any similar transaction, provided that such successor
agrees in writing to be bound by this Agreement. Any permitted assignee shall assume all obligations of its assignor under this
Agreement.

 

13.5         Counterparts.
This Agreement may be executed simultaneously in any number of counterparts, each of which shall be deemed an original but all
of which together shall constitute one and the same instrument.

 

13.6         Paragraph
Headings. The paragraph headings in this Agreement are for convenience of reference only and shall not be deemed to alter or
affect any provision hereof.

 

13.7         Transaction
Expenses. Notwithstanding anything else in this Agreement to the contrary, the parties hereto shall each be responsible for
the payment of (and shall indemnify and hold the other party or parties hereto harmless against) any and all of its own expenses,
including without limitation the fees and expenses of counsel, accountants and other advisers, arising out of or relating directly
or indirectly to the transactions contemplated by this Agreement, whether or not such transactions are consummated in whole or
in part.

 

    	39

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

13.8         Waiver.
The waiver of one breach or default hereunder shall not constitute the waiver of any other or subsequent breach or default.

 

13.9         No
Agency. This Agreement shall not constitute either party the legal representative or agent of the other, nor shall either party
have the right or authority to assume, create, or incur any liability or any obligation of any kind, express or
implied, against or in the name of or on behalf of the other party.

 

13.10         Knowledge.  For
purpose of this Agreement, knowledge shall mean Seller’s actual knowledge, after reasonable investigation, and the actual
knowledge of any employee or member of Seller.

 

IN WITNESS WHEREOF, the parties hereto
have duly executed this Agreement the day and date first above written.

 

	 	SYNTHETIC BIOLOGICS, INC.
	 	 	 
	 	By:	/s/ Jeff Riley
	 	Name:	Jeff Riley
	 	Title:	CEO
	 	 	 
	 	PREV ABR LLC
	 	 	 
	 	By:	/s/ R. Michael Floyd
	 	Name:	R. Michael Floyd
	 	Title:	Managing Member

 

    	40

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

EXHIBIT A

 

INTENTIONALLY OMITTED.

 

    	41

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

EXHIBIT B

 

PATENTS AND JURISDICTIONS

  

	Title	 	MODIFIED BETA-LACTAMASES AND METHODS AND USES RELATED THERETO (P3A)
	Country	 	Date of Filing	 	Application No.	 	Status	 	Patent No.	 	Expiry Date
	EP	 	24-May-2010	 	FI-20105572	 	Lapsed	 	 	 	 
	PCT	 	17-May-2011	 	PCT FI2011/050450	 	WO partly positive	 	 	 	May-31
	Title	 	MODIFIED BETA-LACTAMASES AND METHODS FOR ITS PREPARATION (P2A)
	Country	 	Date of Filing	 	Application No.	 	Status	 	Patent No.	 	Expiry Date
	FI	 	21-Jun-2006	 	20065431	 	Granted	 	FI 119190	 	21-Jun-26
	PCT	 	21-Jun-2007	 	PCT/FI2007/050372	 	WO positive	 	 	 	21 Jun 2026 FI
	National filings	 	21-Dec-2008	 	 	 	 	 	 	 	 
	 	 	NON-SPORULATING BACILLUS SUBTILIS, ITS MANUFACTURE AND USE (HOST PATENT)
	Country	 	Date of Filing	 	Application No.	 	Status	 	Patent No.	 	Expiry Date
	FI	 	6-Nov-2001	 	20012143	 	Granted	 	FI 112666	 	11-Jun-21
	EP	 	3-May-2004	 	02774801.1-2	 	pending	 	 	 	11-May-22
	US	 	5-May-2004	 	10/494,411	 	Granted	 	US 2005/0158843	 	1-Oct-24

 

	Patents Costs	 	 	 	 
	 	 	 	 	 
	HOST Patent	 	 	600	 
	Response to Host Action	 	 	3,900	 
	Response to EPO	 	 	1,800	 
	 	 	 	 	 
	National Phase of PCT P3A:	 	 	 	 
	Aus	 	 	3,250	 
	Canada	 	 	3,250	 
	India	 	 	3,250	 
	South Africa	 	 	3,250	 
	Euro PCT (EP)	 	 	5,700	 
	Brazil	 	 	4,000	 
	China	 	 	4,250	 
	Japan	 	 	5,800	 
	South Korea	 	 	4,650	 
	Russia	 	 	4,400	 
	USA	 	 	4,250	 
	 	 	 	 	 
	Total	 	 	52,350	 

 

    	42

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

EXHIBIT C

 

ESCROW AGREEMENT 

  

ESCROW AGREEMENT, dated
November ___, 2012, by and between by and between SYNTHETIC BIOLOGICS, INC, a Nevada corporation having its principal place of
business at 617 Detroit Street, Suite 100, Ann Arbor, Michigan 48104 (the “Pledgee”), PREV ABR LLC, a Maryland limited
liability company having its principal place of business at 7272 Wisconsin Avenue, Suite 300, Bethesda, Maryland 20814 (the “Pledgor”)
and Gracin & Marlow, LLP, attorneys at law, a New York limited liability partnership with an address at 405 Lexington Avenue,
26th Floor, New York, New York 10174, as escrow agent (the “Escrow Agent”).

 

WHEREAS, Pledgor is
a party to an Asset Purchase Agreement, dated the date hereof (the “Asset Purchase Agreement”), pursuant to which Pledgor
is receiving shares of common stock of Pledgee;

 

WHEREAS, the Pledgor
wishes to pledge Three Hundred Seventy Five Thousand (375,000) shares of the common stock of Pledgee (the “Shares”)
to be held in escrow and released to the parties in accordance with the terms hereof (the Shares are hereinafter referred to as
the “Escrowed Items”);

  

WHEREAS, the Pledgee
and Pledgor wish for the Escrowed Items to be deposited with the Escrow Agent pursuant to the terms of this Escrow Agreement; and

  

WHEREAS, the Escrow
Agent is willing to act as escrow agent pursuant to the terms of this Escrow Agreement with respect to the Escrowed Items;

  

NOW THEREFORE, in
consideration of the premises and the covenants and agreements set forth herein, and for other good and valuable consideration,
the receipt and sufficiency of which is hereby acknowledged, the parties hereto agree as follows:

  

1.          Establishment
of Escrow Account.

  

(a)          Deposit
into Escrow. The Pledgor hereby instructs the Pledgee to deposit the Escrowed Items with the Escrow Agent on the date hereof.

  

(b)          Acceptance.
Upon receipt of the Escrowed Items, the Escrow Agent agrees to hold the Escrowed
Items in accordance with the terms and conditions of this Escrow Agreement (the “Escrow”).

  

2.          Release
from Escrow. Upon receipt of joint written instructions executed by the Pledgor, and Pledgee, the Escrow Agent shall
deliver and release the number of shares of common stock being held as part of the Escrowed Items designated in such joint
written instructions in the amounts and to each person or entity specified in the joint written instructions. If joint
written instructions for all of the Escrowed Items are not provided to the Escrow Agent prior to the six (6) month year
anniversary of execution of this Agreement and the Escrow Agent has not received a copy of any notice of a Claim from Pledgee
under Section 8.2 of the Asset Purchase Agreement, the Escrow Agent shall deliver any remaining Escrowed Items to
Pledgor. If at any time Pledgee and/or Pledgor objects to a distribution requested by
the other, then the Escrow Agent will not release the Escrowed Items but will continue to hold the Escrowed Items
until directed to cause the delivery of the Escrowed Items either: (i) by joint written notice to the Escrow Agent by the
Pledgor and Pledgee (which may be signed in counterparts); (ii) a final order of the applicable arbitrator or court unless
such order is appealed and execution on such order is stayed, in which case a final order of the court considering such
appeal or such motion is vacated; or (iii) otherwise required by laws or court order.. 

 

    	43

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3.          Termination
of this Escrow Agreement. This Escrow Agreement shall terminate when the Escrowed Items shall have been distributed as above
provided subject to the provisions of Section 4 which shall survive any such termination.

 

4.          Rights
and Duties of Escrow Agent.

 

(a)          Duties
Limited. The Escrow Agent undertakes to perform only such duties as are expressly set forth herein, which duties, as hereinabove
set forth in Sections 1, 2 and 3 hereof, shall terminate upon the release of the Escrowed Items as contemplated above. The parties
hereto acknowledge that the duties to be performed by the Escrow Agent hereunder are of a ministerial nature only, and that the
Escrow Agent shall not be liable for any error, omission or action taken by it unless such error, omission or action was the result
of the Escrow Agent's gross negligence or willful default.

 

(b)          Reliance.
The Escrow Agent may rely upon, and shall be protected in acting or refraining from acting upon, any written notice, instruction
or request furnished to it hereunder and believed by it to be genuine and to have been signed or presented by the Pledgee and Pledgor,
provided that any modification of this Escrow Agreement shall be required to be signed by the Pledgee, Pledgor and the Escrow Agent.

 

(c)          Good
Faith. The Pledgee and Pledgor shall jointly indemnify the Escrow Agent and hold it harmless from and against any loss, liability
or expense incurred without gross negligence or bad faith on its part, arising out of or in connection with the Escrow Agreement,
including the costs and expenses of defending itself against any such claim or liability. The Escrow Agent may consult with counsel
of its own choice, and shall have full and complete authorization and no liability for any action taken or suffered by it hereunder
in good faith and in accordance with the opinion of such counsel.

 

(d)          Disputes.
It is understood and agreed that should any dispute arise, the Escrow Agent is authorized and directed to retain the Escrowed Items
or deposit them with a court of competent jurisdiction, until the dispute shall have been settled either by mutual written agreement
of the parties concerned or a by a final order, decree or judgment of a court of competent jurisdiction after the time for appeal
has expired and no appeal has been perfected, but the Escrow Agent shall be under no duty whatsoever to institute or defend any
such proceedings. In addition, the Escrow Agent is acting, and may continue to act, as counsel to the Pledgee in connection with
the subject transaction, including in connection with any dispute as to the proper application of the Escrowed Items, whether or
not the Escrowed Items are being held by the Escrow Agent or have been delivered to a successor escrow agent or a court of competent
jurisdiction.

 

5.          Resignation;
Successor Escrow Agent.

 

(a)          Resignation.
The Escrow Agent may resign at any time by giving five days' notice of such resignation to the Pledgee and Pledgor. Thereafter,
such original Escrow Agent shall have no further obligation hereunder except to hold the Escrowed Items. In such event, the original
Escrow Agent shall refrain from taking any action until it shall receive joint written instructions from the Pledgee and Pledgor
designating a successor escrow agent. Upon receipt of such instructions, the Escrow Agent shall promptly deliver the Escrowed Items
to such successor escrow agent and shall thereafter have no further obligations hereunder. Notwithstanding the foregoing, the Escrow
Agent in its sole discretion may at any time after its resignation deposit the Escrowed Items with a court of competent jurisdiction.

 

    	44

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

(b)          Successor
Escrow Agent. The Pledgee and Pledgor together shall have the right to terminate the appointment of the Escrow Agent hereunder
by giving notice in writing of such termination to the Escrow Agent, specifying the date upon which such termination shall take
effect. In the event of such termination, the Pledgee and Pledgor agree that they will jointly appoint a successor escrow agent
at or before the time such notice becomes effective, and the Escrow Agent hereby agrees that it shall turn over and deliver the
Escrowed Items to such successor escrow agent. Upon delivery of the Escrowed Items, the Escrow Agent shall be discharged of any
further duties under this Escrow Agreement.

 

6.          Fees
and Expenses of the Escrow Agent. The Pledgee and Pledgor agree, jointly and severally, to (i) pay the Escrow Agent Two Thousand
Five Hundred Dollars ($2,500) upon execution of this Escrow Agreement; and (ii) reimburse the Escrow Agent for all necessary expenses,
disbursements and advances (including reasonable attorneys' fees) incurred or made by it in connection with carrying out its duties
hereunder. The liability of the Pledgee and Pledgor under this Section 6 shall be joint and several.

 

7.          Waivers
and Modifications. This Escrow Agreement may be amended, modified, extended, superseded or canceled, and any of the terms,
covenants, representations, warranties or conditions hereof may be waived, only by a written instrument executed by all of the
parties hereto. The failure of any party at any time or times to require performance of any provision hereof shall in no manner
affect the right of such party at a later time to enforce the same. No waiver by any party of the breach of any term, covenant,
representation or warranty contained in this Escrow Agreement as a condition to such party's obligation hereunder shall release
or affect any liability resulting from such breach, and no waiver of any nature, whether by conduct or otherwise, in anyone or
more instances, shall be deemed to be construed as a further or continuing waiver of any such condition or breach, a waiver of
any other condition or a waiver of any breach of any other condition, term, covenant, representation or warranty of this Escrow
Agreement.

 

8.          Notices.
Any notice, demand or other communication required or permitted to be given pursuant to this Escrow Agreement shall have been sufficiently
given for all purposes (a) if delivered personally to the party or to an executive officer of the party to whom such notice, demand
or other communication is directed on the date of such personal delivery; or (b) if sent by registered or certified mail, postage
prepaid, addressed to the party to whom such notice, demand or other communication is directed at its address set forth below on
the fifth business day after the date on which it was deposited in a regularly maintained receptacle for the deposit of United
States mail; or (c) if sent by facsimile transmission, or electronic mail, with a copy mailed on the same day
by first class mail, postage prepaid. 

 

If to the Pledgee:

 

Synthetic Biologics, Inc.

617 Detroit Street

Ann Arbor, Michigan, 48104

Facsimile: 734-332-7878

Email:jriley@synethticbiologics.com

Attention: Jeffrey Riley

 

If to Pledgor:

 

Prev ABR LLC

7272 Wisconsin Avenue

Bethesda, Maryland 20814

Facsimile: (301) 986 4811

Email Address:mfloyd@lsmgrp.com

Attention: R Michael Floyd

 

    	45

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

If to the Escrow Agent:

 

Gracin & Marlow, LLP

405 Lexington Avenue, 26th Floor

New York, New York 10174

Facsimile: (212) 208-4657

Attention: Leslie Marlow

  

9.          No
Assignment. This Escrow Agreement shall be binding upon the successors and permitted assigns of the parties hereof. No assignment
of any rights or delegation of any obligations provided for herein may be made by any party hereto without the express written
consent of all other parties hereto, except for the provisions of Section 5 respecting successor escrow agents.

 

10.         Entire
Agreement. This Escrow Agreement contains the entire agreement among the parties hereto with respect to the subject matter
hereof, and there are no representations, warranties, understandings or agreements other than those expressly set forth herein.

  

11.         Further
Assurances. If at any time any party hereto shall consider or be advised that any further agreements, assurances or other documents
are reasonably necessary or desirable to carry out the provisions hereof and the transactions contemplated hereby, the parties
hereto shall execute and deliver any and all such agreements or other documents, and do all things necessary or appropriate to
carry out fully the provisions hereof.

 

12.         Governing
Law. The validity of this Escrow Agreement and the rights, obligations and relations of the parties hereunder shall be construed
and determined under and in accordance with the laws of the State of New York without giving effect to the conflict of laws rules
of such State. ALL PARTIES HEREBY SUBMIT TO THE JURISDICTION OF THE STATE OF NEW YORK IN CONNECTION WITH ANY LEGAL PROCEEDINGS
COMMENCED IN CONNECTION WITH THIS ESCROW AGREEMENT.

 

13.         Counterparts.
This Escrow Agreement may be executed in counterparts, each of which shall be deemed an original and all of which together shall
constitute one and the same instrument.

 

14.         Section
Headings. The section headings contained in this Escrow Agreement are inserted for purposes of convenience of reference only
and shall not affect the meaning or interpretation hereof.

 

IN WITNESS WHEREOF, the parties have executed
this Escrow Agreement as of the date first above written.

 

	SYNTHETIC BIOLOGICS, INC.
	 
	By:	 	 
	Name:	 	 
	Title:	 	 

 

    	46

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

	PREV ABR LLC	 
	 	 
	By:	 	 
	Name:	 
	Title:	 
	 	 
	ESCROW AGENT:	 
	 	 
	GRACIN & MARLOW, LLP	 
	 	 
	By:	 	 
	Name:  Leslie Marlow	 
	Title: Partner	 

  

    	47

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

EXHIBIT D

 

MILESTONE PAYMENTS 

  

EACH OF THE FOLLOWING PAYMENTS OR STOCK
ISSUANCES SHALL BE DUE AND PAYABLE OR ISSUED, AS THE CASE MAY BE, WITHIN 5 BUSINESS DAYS AFTER ACHIEVING THE RESPECTIVE MILESTONE
AND AFTER RECEIPT OF NECESSARY REGULATORY APPROVALS

 

Filing of an IND: USD $***** in cash

 

Initiation of Phase 1 (first subject dosed):
USD $***** 50% of which will be paid in cash and the remaining 50% to be paid in the stock equivalent. At Seller’s option,
the full milestone may be paid in stock.

 

Commencement of Phase 2 (first subject
dosed): USD $***** 50% of which will be paid in cash and the remaining 50% to be paid in the stock equivalent. At Seller’s
option, the full milestone may be paid in stock.

 

Commencement of Phase 3 (first patient
dosed): USD $***** 50% of which will be paid in cash and the remaining 50% to be paid in the stock equivalent. At Seller’s
option, the full milestone may be paid in stock.

 

BLA Filing: USD $***** 50% of which will
be paid in cash and the remaining 50% to be paid in the stock equivalent. At Seller’s option, the full milestone may be paid
in stock.

 

Filing BLA in any other territory: USD
$***** 50% of which will be paid in cash and the remaining 50% to be paid in the stock equivalent. At Seller’s option, the
full milestone may be paid in stock.

 

BLA Approval: USD $***** 50% of which will
be paid in cash and the remaining 50% to be paid in the stock equivalent. At Seller’s option, the full milestone may be paid
in stock.

 

BLA Approval in any other territory: USD
$***** 50% of which will be paid in cash and the remaining 50% to be paid in the stock equivalent. At Seller’s option, the
full milestone may be paid in stock.

 

Any and all payments in stock contemplated
in this Agreement shall be subject to prior approval of the NYSE MKT LLC or any other exchange on which Synthetic’s securities
shall be listed. If such exchange approval is not received, such payment shall be made in each case based upon the average of the
opening and closing prices of Synthetic’s stock on the date such milestone is achieved (or in the event the milestone is
achieved on a date in which the stock market is closed on the next business date for such market). Seller acknowledges that its
right to be paid in stock is subject to a limitation such that the aggregate maximum number of shares of Synthetic’s stock
that may be issued in accordance with the terms of this Agreement, including but not limited to all issuances set forth on this
Exhibit D and the 625,000 shares to be issued in accordance with Section 2.4(b) of this Agreement, shall not exceed 19.99% of Synthetic’s
outstanding number of shares of common stock on the date of execution of this Agreement; provided, however, that Synthetic shall
have the right, in its sole discretion, to obtain shareholder approval to issue shares of stock in excess of the 19.99% cap in
accordance with all applicable exchange requirements and if such shareholder approval is obtained then Synthetic shall have the
right, in its sole discretion, to make such payments in shares of its common stock. For purposes of the Asset Purchase Agreement
all of the countries located in Europe shall be one territory, Korea, Japan and India shall be one territory, South America including
Brazil shall be one territory and The United States and Canada shall be one territory.

 

    	48

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

EXHIBIT E

 

SECTION 2.5

 

I.R.C. SECTION 1060 ALLOCATION

 

For tax purposes, the Seller and Buyer shall allocate the purchase
price as follows:

 

1.     80%
to the patents and patent applications relating to the CDAD program; 

2.     10%
to the preclinical package for P1A, P2A and P3A 

3.     10%
for the master cell banks or P1A, P2A, and P3A

 

    	49

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

EXHIBIT F

 

ASSIGNMENT AND BILL OF SALE

 

KNOW ALL MEN BY
THESE PRESENTS, that Synthetic Biologics, Inc., a Nevada corporation having its principal place of business at 617 Detroit
Avenue, Suite 100, Ann Arbor, Michigan 48104 ("Buyer"), for and in consideration of the receipt of the consideration
set forth in the Asset Purchase Agreement executed on the date hereof between the Buyer and PREV ABR LLC, a Maryland limited liability
company, having its principal place of business at 7201 Wisconsin Avenue, Bethesda, Maryland 20814 (“PrevAb”) and other
good and valuable consideration in full payment for the assets hereinafter specified, the receipt and sufficiency of which is hereby
acknowledged, has granted, bargained, sold and by these presents does grant, bargain, sell, convey and deliver to Buyer, and its
successors and assigns, the following assets:

 

PrevAb’s CDAD
program including any and all of the following assets of PrevAb, including any and all rights and benefits
constituting and relating to PrevAb's β-lactamase technology and all other biomedical or pharmaceutical technologies of PrevAb
and all β-lactamase products detained and/or developed with the aforementioned technologies, including without limitation
the lead P1A, P2A and P3A-based products in preclinical and clinical phases  (the "Program") and all tangible
and intangible intellectual property and know how exclusively related thereto including the following:

 

(a)          all
methods and data sets, and all technical documentation pertaining to the Program, including any specifications, flow charts, diagrams,
lab results and any and all notes, all inventor notebook pages specific to the Program, plans and other documentation describing
problems, future directions or other matters exclusively related to the Program;

 

(b)          (i)
all patents, patent rights, copyrights, trademarks, trademark rights, tradenames, tradename rights and patent, copyright or trademark
applications exclusively respecting the Program and related intellectual property; (ii) all reissues, reexaminations, extensions,
continuations, continuations-in-part, continuing prosecution applications, requests for continuing examinations, divisions and
registrations of any item in any of the foregoing categories; (iii) foreign counterparts of any of the foregoing; (iv) all patent
and patent applications claiming any right of priority to or through the patent applications of the patents listed on Exhibit
B hereto; (v) all rights to apply in all countries of the world for patents certificates of invention, utility models, industrial
design protections, design patent protections, or other governmental grants or issuances of any type related to any item in any
of the foregoing categories (i) through (v), including, without limitation, under the Paris Convention for the Protection of Industrial
Property, the International Patent Cooperation Treaty, or any other convention, treaty, agreement, or understanding; (vi) all invention,
invention disclosures and discoveries described in any of the patents listed on Exhibit B hereto that are included in any
claim in such patents, and/or are subject matter capable of being reduced to a patent claim in a reissue or reexamination proceeding
brought on any of the patents; (vii) all causes of action (whether known or unknown, or whether currently pending, filed or otherwise)
and other enforcement rights under, or on account of, any of the patents and/or rights (as described on Exhibit B); (viii)
all rights to collect royalties and other payments under or on account of the patents or any item in any categories (i) through
(vii); (ix) all ideas, know-how, trade secrets, inventions, invention disclosures, discoveries, technology, designs and any other
proprietary rights which Seller owns, in each case with respect to any of the above, pertaining exclusively to the Program (collectively,
"Proprietary Rights"); and (x) a list of upcoming filings, all US Patent and Trademark Office and other patentability
assessments;

 

    	50

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

(c)          all
cGMP and non-cGMP material and master call banks of P1A, P2A and P3A and all other tangible assets related thereto;

 

(d)          any
and all U.S. and international investigational new drug applications (IND) and pre-INDs of Seller;

 

(e)          all
grants and other non-dilutive funding sources associated with the CDAD Program if legally assignable or transferable by Seller
to Buyer;

 

(f)          all
scientific consulting agreements with the members of PrevAb’s scientific advisory board;

 

(g)          information
and know-how related to research, development, manufacture and/or business (commercial/marketing), used or held for use in connection
with the Program;

 

(k)          any
and all health and regulatory registrations, approvals and/or applications and related documentation for the Program;

 

(l)          any
and all drugs, formulations and user devices, applications, and safety data; and

 

(m)         all
other information, documentation and goodwill relating to the Program; and

 

(n)         all
regulatory files (paper and electronic) or so-called regulatory files and records of communications and filings with any and all
regulatory authorities in both paper and electronic form.

 

TO HAVE AND TO HOLD the said assets
unto Buyer, its successors and assigns, to and for its own use, forever.

 

1.          PrevAb
warrants to Buyer its successors and assigns, that at the time of delivery of this Bill of Sale to Buyer, PrevAb has good and valid
title to said assets to the same extent assigned to it by PrevAb and good and lawful right to grant, bargain, sell, convey and
deliver said assets as aforesaid and that the title to said assets are as of the date of delivery of said assets to Buyer, free
and clear of all claims, liens, pledges, security interests and other encumbrances of any nature whatsoever(“Liens”).
PrevAb further warrants that upon delivery of this Bill of Sale to Buyer, Buyer shall have good and valid legal title to the assets
described in this Bill of Sale, free and clear of all claims, liens, pledges, security interests and other encumbrances of any
nature whatsoever. The foregoing is subject to any Liens that were unknown to PrevAb but were in effect at the time of the sale
of the Assets to Buyer by PrevAb.

 

2.          PrevAb
agrees to execute and deliver to Buyer such other documents and instruments of sale, conveyance, transfer and assignment, satisfactory
in form and substance to Buyer, as may be reasonably requested by Buyer in order to effect PrevAb’s assignment of assets
hereunder.

 

    	51

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

IN WITNESS WHEREOF, the parties hereto
have caused these presents to be executed as of the ___ day of November, 2012.

 

	 	PREVABR LLC
	 	 
	 	By:	    
	 	Name:
	 	Title:
	 	 
	 	SYNTHETIC BIOLOGICS, INC.
	 	 
	 	By:	   
	 	Name;
	 	Title:

 

    	52

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

Exhibit A

 

Intentionally Omitted.

 

    	53

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

Exhibit B

 

	Title	MODIFIED BETA-LACTAMASES AND METHODS AND USES RELATED THERETO (P3A)

	Country	 	Date of
 Filing	 	Application No.	 	Status	 	Patent No.	 	Expiry Date
	EP	 	24-May-2010	 	FI-20105572	 	Lapsed	 	 	 	 
	PCT	 	17-May-2011	 	PCT FI2011/050450	 	WO partly positive	 	 	 	May-31

 

	Title	MODIFIED BETA-LACTAMASES AND METHODS FOR ITS PREPARATION (P2A)

	Country	 	Date of
 Filing	 	Application No.	 	Status	 	Patent No. 	 	Expiry Date
	FI	 	21-Jun-2006	 	20065431	 	Granted	 	FI 119190	 	21-Jun-26
	PCT	 	21-Jun-2007	 	PCT/FI2007/050372	 	WO positive	 	 	 	21 Jun 2026 FI
	National filings	 	21-Dec-2008	 	 	 	 	 	 	 	 

 

	 	NON-SPORULATING BACILLUS SUBTILIS, ITS MANUFACTURE AND USE (HOST PATENT)

	Country	 	Date of
 Filing	 	Application No.	 	Status	 	Patent No. 	 	Expiry Date
	FI	 	6-Nov-2001	 	20012143	 	Granted	 	FI 112666	 	11-Jun-21
	EP	 	3-May-2004	 	02774801.1-2	 	pending	 	 	 	11-May-22
	US	 	5-May-2004	 	10/494,411	 	Granted	 	US 2005/0158843	 	1-Oct-24

 

    	54

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

  

EXHIBIT G

 

INTENTIONALLY OMITTED.

 

    	55

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

  

EXHIBIT H

 

ASSIGNMENT

  

PREV ABR LLC
with offices at 7272 Wisconsin Avenue, Suite 300, Bethesda, Maryland 20814, the undersigned,
for good and valuable consideration, the receipt of which is hereby acknowledged, confirm that we have freely assigned, and do
hereby freely assign, and transfer to SYNTHETIC BIOLOGICS, INC., a corporation, with offices at 617
Detroit Street, Ann Arbor, Michigan 48104, and its successors, assigns and legal representatives, all hereinafter
referred to as the ASSIGNEES: (1) our entire right, title and interest for the United States and in all countries, in and
to any and all inventions, discoveries and applications which are disclosed in the applications listed in “Schedule A”,
including any subsequently filed applications, which claim priority to, and benefit of, the applications
listed on “Schedule A”, including any renewals, revivals, reissues, reexaminations, extensions,
continuations and divisions thereof and any substitute applications therefore; (2) the full and complete right to file patent
applications in the name of the ASSIGNEE, its designee, or in my name as the ASSIGNEE, or its designee's election, on the aforesaid
inventions, discoveries and applications in all countries of the world; (3) the entire right, title and interest in and to
any Letters Patent which may issue thereon in the United States or in any country, and any renewals, revivals, reissues, reexaminations
and extensions thereof, and any patents of confirmation, registration and importation of the same; and (4) the entire right,
title and interest in all Convention and Treaty Rights of all kinds thereon, including without limitation all rights of priority
in any country of the world, in and to the above inventions, discoveries and applications.

 

We hereby authorize
and request the competent authorities to grant and to issue any and all such Letters Patent in the United States and throughout
the world to the ASSIGNEES of the entire right, title and interest therein, as fully and entirely as the same would have been held
and enjoyed by me/us had this assignment, sale and transfer not been made.

 

We agree, at any time,
upon the request of the ASSIGNEES, to execute and to deliver to the ASSIGNEES any additional applications for patents for said
inventions and discoveries, or any part or parts thereof, and any applications for patents of confirmation, registration and importation
based on any Letters Patent issuing on said inventions, discoveries, or applications and divisions, continuations, renewals, revivals,
reissues, reexaminations and extensions thereof.

 

We further agree at
any time to execute and to deliver upon request of the ASSIGNEES such additional documents, if any, as are necessary or desirable
to secure patent protection on said inventions, discoveries and applications throughout all countries of the world, and otherwise
to do the necessary to give full effect to and to perfect the rights of the ASSIGNEES under this Assignment, including the execution,
delivery and procurement of any and all further documents evidencing this assignment, transfer and sale as may be necessary or
desirable.

  

We hereby covenant
that no assignment, sale, agreement or encumbrance has been or will be made or entered into which would conflict with this assignment.

 

    	56

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

  

We further covenant
that ASSIGNEES will, upon its request, be provided promptly with all pertinent facts and documents relating to said invention and
said Letters Patent and legal equivalents as may be known and accessible to ASSIGNOR and will testify as to the same in any interference,
litigation or proceeding related thereto and will promptly execute and deliver to ASSIGNEES or its legal representatives any and
all papers, instruments or affidavits required to apply for, obtain, maintain, issue and enforce said application, said invention
and said Letters Patent and said equivalents thereof which may be necessary or desirable to carry out the purposes thereof.

 

	Date:	 	 	 	 
	 	 	 	 	Signature of: 
	 	 	 	 	On Behalf of: PREV ABR LLC

  

State of ______________________________

County of ____________________________

 

On this ______ day of ________________, 20__, before me, the
undersigned notary public, personally appeared ________________________ proved to me through satisfactory evidence of identification,
which was a __________________, to be the person whose name is signed on this document and who swore or affirmed to me that
the contents of this document are truthful and accurate to the best of his/her knowledge and belief.

 

	 	 
	 	Notary Public
	 	 
	 	My commission expires  	  

  

    	57

    	Portions herein identified by [*****] have been omitted pursuant to a request for confidential treatment under Rule 24b-2 of the Securities Exchange Act of 1934, as amended. A complete copy of this document has been filed separately with the Securities and Exchange Commission.

    

 

Schedule A

 

	Country	 	Date of Filing	 	Application No.	 	Status	 	Patent No.	 	Expiry Date
	 	 	 	 	 	 	 	 	 	 	 
	EP	 	24-May-2010	 	FI20105572	 	Lapsed	 	 	 	 
	PCT	 	17-May-2011	 	PCT FI2011/050450	 	WO partly positive	 	 	 	May-31

  

	Country	 	Date of Filing	 	Application No.	 	Status	 	Patent No.	 	Expiry Date
	 	 	 	 	 	 	 	 	 	 	 
	FI	 	21-June-2006	 	20065431	 	Granted	 	FI119190	 	21-June-26
	PCT	 	21-Jun-2007	 	PCT/FI2007/050372	 	WO positive	 	 	 	21 Jun 2026 FI
	National filings	 	21-Dec-2008	 	 	 	 	 	 	 	 

  

	Country	 	Date of Filing	 	Application No.	 	Status	 	Patent No.	 	Expiry Date
	 	 	 	 	 	 	 	 	 	 	 
	FI	 	28-Nov-2006	 	20065757	 	Granted	 	FI119678	 	28-Dec-26
	PCT	 	21-Nov-2007	 	PCT7FI2007/05062	 	WO positive	 	 	 	28 Dec 2028 FI
	National Filings	 	28-May-2009	 	 	 	 	 	 	 	 

  

	Country	 	Date of Filing	 	Application No.	 	Status	 	Patent No.	 	Expiry Date
	 	 	 	 	 	 	 	 	 	 	 
	FI	 	6-Nov-2001	 	20012143	 	Granted	 	FI112666	 	11-June-21
	EP	 	3-May-2004	 	02774801.1-2	 	Pending	 	 	 	11-May-22
	US	 	5-May-2004	 	10/494,411	 	Granted	 	US2005/0158843	 	1-Oct-24

 

    	58

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