Document:

EX-10.1

 Exhibit 10.1 
 AMENDMENT NO. 1 TO 
 EMPLOYMENT AGREEMENT 

THIS AMENDMENT NO. 1 TO EMPLOYMENT AGREEMENT (this “Amendment”) is made and entered into as of December 23, 2013
by and between REGADO BIOSCIENCES, INC. (the “Company”) and DAVID J. MAZZO, Ph.D. (the “Executive”). 
 W I T N E S S E T H: 
 WHEREAS, the Company and the Executive are
parties to that certain amended and restated employment agreement dated May 16, 2013 (the “Employment Agreement”). Capitalized terms used in this Amendment and not otherwise defined herein shall have the meaning ascribed to
them in the Employment Agreement; and 
 WHEREAS, the Company and the Executive desire to amend certain terms of the
Employment Agreement as provided for herein. 
 NOW THEREFORE, in consideration of these premises, the mutual agreements
and covenants hereinafter set forth, and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto hereby agree as follows: 

1. Section 3.1(c) of the Employment Agreement is hereby amended by adding the following language to the end of
Section 3.1 (c): 
 “For calendar year 2014 and 2015 only, in the event of achievement of a Performance
Event (as defined below) at any time on or prior to December 31, 2015, the Executive will receive a lump sum cash bonus (the “Performance Event Bonus”) for the calendar year during which the Performance Event occurs equivalent
to 100% of Base Salary for such calendar year during which the Performance Event occurs (which shall be in lieu of the Target Annual Bonus amount for 2014 or 2015, as applicable), payable in the same calendar year in which the Performance Event (if
any) occurs or within the first 75 days of the following calendar year, subject to the Executive’s continued active employment with the Company at the time of such payment. As used in this Section 3.1(c), “Performance
Event” means, at any time on or before December 31, 2015, but before the Company raises cumulatively $90,000,000 through a financing or series of financings, the Company’s consummation of a transaction resulting in a merger, sale
of equity to a strategic partner at a price greater than then current Fair Market Value as defined in the 2013 Plan (as defined below), sale of assets, partnering, joint venture or licensing transaction, in each case yielding sufficient net cash
proceeds to the Company to reduce the Company’s capital needs to complete the REGULATE-PCI study by at least $45,000,000, as determined by the Board of Directors or the Compensation Committee. For the avoidance of doubt, the Executive shall
only be eligible to receive one Performance Event Bonus (i.e., in no event is the Executive eligible to receive a Performance Event Bonus for both 2014 and 2015). If the Executive does not become entitled to the Performance Event Bonus for
2014 or 2015, then he shall remain eligible for the regular Annual Bonus for 2014 and 2015 in accordance with the terms provided herein.” 

  
 1 

 2. Section 5.18(a) and Section 5.18(b) of the Employment Agreement
are hereby amended in their entirety to read as follows: 
 “(a) If any payment, benefit or distribution of any type to or
for the benefit of the Executive, whether paid or payable, provided or to be provided, or distributed or distributable pursuant to the terms of this Agreement or otherwise (collectively, the “Parachute Payments”) would
(i) constitute a “parachute payment” within the meaning of Section 280G of the Code, and (ii) subject the Executive to the excise tax imposed under Section 4999 of the Code (the “Excise Tax”), the
Parachute Payments shall be reduced so that the maximum amount of the Parachute Payments (after reduction) shall be one dollar ($1.00) less than the amount which would cause the Parachute Payments to be subject to the Excise Tax; provided that the
Parachute Payments shall only be reduced to the extent the after-tax value of amounts received by the Executive after application of the above reduction would exceed the after-tax value of the amounts received without application of such reduction.
For this purpose, the after-tax value of an amount shall be determined taking into account all federal, state, and local income, employment and excise taxes applicable to such amount. Unless the Executive shall have given prior written notice to the
Company to effectuate a reduction in the Parachute Payments if such a reduction is required, which notice shall be consistent with the requirements of Section 409A to avoid the imputation of any tax, penalty or interest thereunder, then the
Company shall reduce or eliminate the Parachute Payments by first reducing or eliminating any cash payments (with the payments to be made furthest in the future being reduced first), then by reducing or eliminating accelerated vesting of stock
options or similar awards, and then by reducing or eliminating any other remaining Parachute Payments; provided, that no such reduction or elimination shall apply to any non-qualified deferred compensation amounts (within the meaning of
Section 409A) to the extent such reduction or elimination would accelerate or defer the timing of such payment in manner that does not comply with Section 409A. 
 (b) An initial determination as to whether (x) any of the Parachute Payments received by the Executive in connection with the occurrence of a change in the ownership or control of the Company or in
the ownership of a substantial portion of the assets of the Company shall be subject to the Excise Tax, and (y) the amount of any reduction, if any, that may be required pursuant to the previous paragraph, shall be made by an independent
accounting firm selected by the Company (the “Accounting Firm”) prior to the consummation of such change in the ownership or effective control of the Company or in the ownership of a substantial portion of the assets of the Company.
The Company will bear all expenses with respect to the determinations by such Accounting Firm required to be made hereunder. The Executive shall be furnished with notice of all determinations made as to the Excise Tax payable with respect to the
Executive’s Parachute Payments, together with the related calculations of the Accounting Firm, promptly after such determinations and calculations have been received by the Company.” 

3. Except as expressly amended hereby, all provisions of the Employment Agreement shall remain unmodified and in full force and effect.

 [Signature Page Follows] 

  
 2 

 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the day and year first
above written. 
  

			
	 COMPANY
  

Regado Biosciences, Inc.

		
	By:	 	/s/ Dennis G. Podlesak
	Name:	 	Dennis G. Podlesak
	Title:	 	Chairman of Board

  

			
	EXECUTIVE
		
		 	/s/ David J. Mazzo, Ph.D.
		 	David J. Mazzo, Ph.D.

  
 3EX-10.2

 Exhibit 10.2 
 AMENDMENT NO. 1 TO 
 EMPLOYMENT AGREEMENT 

THIS AMENDMENT NO. 1 TO EMPLOYMENT AGREEMENT (this “Amendment”) is made and entered into as of December 23, 2013
by and between REGADO BIOSCIENCES, INC. (the “Company”) and STEVEN L. ZELENKOFSKE, D.O. (the “Executive”). 
 W I T N E S S E T H: 
 WHEREAS, the Company and the Executive are
parties to that certain amended and restated employment agreement dated May 16, 2013 (the “Employment Agreement”). Capitalized terms used in this Amendment and not otherwise defined herein shall have the meaning ascribed to
them in the Employment Agreement; and 
 WHEREAS, the Company and the Executive desire to amend certain terms of the
Employment Agreement as provided for herein 
 NOW THEREFORE, in consideration of these premises, the mutual agreements
and covenants hereinafter set forth, and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto hereby agree as follows: 

1. Section 3.2 of the Employment Agreement is hereby amended by adding the following language to the end of
Section 3.2: 
 “Further, but without duplication, the Company will reimburse the Executive for (a) the
reasonable expenses the Executive incurs for travel between his home in Center Valley, PA and the Company’s office in Basking Ridge, New Jersey and (b) the reasonable expenses the Executive incurs in connection with his lodging in the
Basking Ridge, New Jersey area (but, in each case, specifically excluding any personal travel or lodging expenses); provided, however, in no event shall the reimbursement amount for such travel and lodging expenses exceed $25,000 per year. In order
to receive any such reimbursements, the Executive shall furnish to the Company documentary evidence of each such expense in the form required to comply with the Company’s policies in place from time to time.” 

2. Section 5.17(a) and Section 5.17(b) of the Employment Agreement are hereby amended in their entirety to read
as follows: 
 “(a) If any payment, benefit or distribution of any type to or for the benefit of the Executive, whether paid
or payable, provided or to be provided, or distributed or distributable pursuant to the terms of this Agreement or otherwise (collectively, the “Parachute Payments”) would (i) constitute a “parachute payment” within
the meaning of Section 280G of the Code, and (ii) subject the Executive to the excise tax imposed under Section 4999 of the Code (the “Excise Tax”), the Parachute Payments shall be reduced so that the maximum amount of the
Parachute Payments (after reduction) shall be one dollar ($1.00) less than the amount which would cause the Parachute Payments to be subject to the Excise Tax; provided that the Parachute Payments shall only be reduced to the extent the after-tax
value of amounts received by the Executive after 

  
 1 

 
application of the above reduction would exceed the after-tax value of the amounts received without application of such reduction. For this purpose, the after-tax value of an amount shall be
determined taking into account all federal, state, and local income, employment and excise taxes applicable to such amount. Unless the Executive shall have given prior written notice to the Company to effectuate a reduction in the Parachute Payments
if such a reduction is required, which notice shall be consistent with the requirements of Section 409A to avoid the imputation of any tax, penalty or interest thereunder, then the Company shall reduce or eliminate the Parachute Payments by
first reducing or eliminating any cash payments (with the payments to be made furthest in the future being reduced first), then by reducing or eliminating accelerated vesting of stock options or similar awards, and then by reducing or eliminating
any other remaining Parachute Payments; provided, that no such reduction or elimination shall apply to any non-qualified deferred compensation amounts (within the meaning of Section 409A) to the extent such reduction or elimination would
accelerate or defer the timing of such payment in manner that does not comply with Section 409A. 
 (b) An initial
determination as to whether (x) any of the Parachute Payments received by the Executive in connection with the occurrence of a change in the ownership or control of the Company or in the ownership of a substantial portion of the assets of the
Company shall be subject to the Excise Tax, and (y) the amount of any reduction, if any, that may be required pursuant to the previous paragraph, shall be made by an independent accounting firm selected by the Company (the “Accounting
Firm”) prior to the consummation of such change in the ownership or effective control of the Company or in the ownership of a substantial portion of the assets of the Company. The Company will bear all expenses with respect to the
determinations by such Accounting Firm required to be made hereunder. The Executive shall be furnished with notice of all determinations made as to the Excise Tax payable with respect to the Executive’s Parachute Payments, together with the
related calculations of the Accounting Firm, promptly after such determinations and calculations have been received by the Company.” 
 3. Except as expressly amended hereby, all provisions of the Employment Agreement shall remain unmodified and in full force and effect. 

[Signature Page Follows] 

  
 2 

 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the day and year first
above written. 
  

			
	 COMPANY
  

Regado Biosciences, Inc.

		
	By:	 	/s/ David J. Mazzo
	Name:	 	David J. Mazzo
	Title:	 	Chief Executive Officer

  

			
	EXECUTIVE
		
		 	/s/ Steven L. Zelenkofske
		 	Steven L. Zelenkofske, D.O.

  
 3

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00224-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00224-of-00352.parquet"}]]