Document:

THIRD
AMENDMENT TO LOAN AND SECURITY AGREEMENT

 

THIS THIRD AMENDMENT TO
LOAN AND SECURITY AGREEMENT (this “Third Amendment” or this “Amendment”) is entered into
as of May 28, 2013, by and among HORIZON CREDIT II LLC, a Delaware limited liability company
(“Borrower”), the lenders identified on the signature page hereof (such lenders, together with their
respective successors and assigns, are referred to hereinafter each individually as a “Lender” and collectively
as the “Lenders”), and WELLS FARGO CAPITAL FINANCE, LLC, a Delaware limited liability company (“WFCF”),
as the arranger and administrative agent for the Lenders (in such capacity, “Agent”), with reference to the
following facts, which shall be construed as part of this Third Amendment:

 

RECITALS

 

A.          Borrower, Lenders
and Agent have entered into that certain Loan and Security Agreement dated as of July 14, 2011, as amended by that certain
First Amendment to Loan and Security Agreement dated as of May 30, 2012 and that certain Second Amendment to Loan and Security
Agreement dated as of December 17, 2012 (as amended or modified from time to time, the “Loan Agreement”),
pursuant to which Lenders and Agent are providing financial accommodations to or for the benefit of Borrower upon the terms and
conditions contained therein. Unless otherwise defined herein, capitalized terms or matters of construction defined or established
in the Loan Agreement shall be applied herein as defined or established therein.

 

B.          Borrower
has requested that Lenders and Agent agree to amend certain provisions of the Loan Agreement,
and Lenders and Agent are willing to do so to the extent provided in, and subject to the terms and conditions of, this Third Amendment.

 

C.          As
of the date hereof, WFCF is the sole Lender under the Loan Agreement.

 

AGREEMENT

 

NOW, THEREFORE, in consideration
of the continued performance by Borrower of its promises and obligations under the Loan Agreement and the other Loan Documents,
and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, Borrower, Lenders
and Agent hereby agree as follows:

 

1.          Ratification
of Existing Loan Documents. Each of the parties acknowledges, confirms, and ratifies the provisions of the Loan Agreement and
the other Loan Documents, which shall be unmodified and shall continue to be in full force and effect in accordance with their
terms except as expressly provided under this Third Amendment.

 

2.          Amendments
to the Loan Agreement. The Loan Agreement is hereby amended as follows:

 

2.1          Addition
of New Definition. Section 1.1 of the Loan Agreement is amended by adding in appropriate alphabetical order the following
new definition of the term “Third Amendment”:

 

    	- 1 -

    	 

    

 

“Third Amendment”
means the Third Amendment to Loan and Security Agreement, dated as of May 28, 2013, by and among Lenders, Agent and Borrower.

 

2.2          Amendment
to LIBOR Rate Margin. Section 1.1 of the Loan Agreement is amended by deleting the existing text of the definition of
the term “LIBOR Rate Margin,” and replacing it with the following amended and restated version thereof:

 

“LIBOR Rate Margin”
means (a) from July 14, 2011, through and including April 30, 2013, four percent (4.00%) and (b) from May 1, 2013 through and including
the Maturity Date, three and one-quarter of one percent (3.25%).

 

2.3          Amendment
to List of Approved Third-Party Lenders. Schedule A-1 to the Loan Agreement is amended by deleting the existing text
thereof and replacing it with the amended and restated version thereof attached as Exhibit A to this Third Amendment.

 

3.          Conditions
Precedent. Notwithstanding any other provision of this Third Amendment, this Third Amendment shall be of no force or effect,
and Lenders and Agent shall not have any obligations hereunder, unless and until each of the following conditions have been satisfied:

 

3.1          Third
Amendment and other Documents in Connection therewith. Agent shall have received this Third Amendment, duly executed by Borrower,
each Lender, and Agent; and

 

3.2          No
Default or Event of Default. No Default or Event of Default shall have occurred and be continuing.

 

4.          Representations
and Warranties regarding Loan Agreement. Borrower hereby represents and warrants that the representations and warranties contained
in the Loan Agreement were true and correct in all material respects when made and, except to the extent that (a) a particular
representation or warranty by its terms expressly applies only to an earlier date, or (b) Borrower has previously advised
Agent in writing as contemplated under the Loan Agreement, are true and correct in all material respects as of the date hereof.
Borrower hereby further represents and warrants that no event has occurred and is continuing, or would result from the transactions
contemplated under this Third Amendment, that constitutes or would constitute a Default or an Event of Default.

 

5.          Miscellaneous.

 

5.1          Headings.
The various headings of this Third Amendment are inserted for convenience of reference only and shall not affect the meaning or
interpretation of this Third Amendment or any provisions hereof.

 

5.2          Counterparts.
This Third Amendment may be executed by the parties hereto in several counterparts, each of which shall be deemed to be an original
and all of which together shall be deemed to be one and the same instrument. Delivery of an executed counterpart of a signature
page to this Third Amendment by telefacsimile or other electronic method of transmission shall be equally as effective as delivery
of an original executed counterpart of this Third Amendment. Any party delivering an executed counterpart of this Third Amendment
by telefacsimile or other electronic method of transmission also shall deliver an original executed counterpart of this Third Amendment
but the failure to deliver an original executed counterpart shall not affect the validity, enforceability, and binding effect of
this Third Amendment.

 

    	- 2 -

    	 

    

 

5.3          Interpretation.
No provision of this Third Amendment shall be construed against or interpreted to the disadvantage of any party hereto by any court
or other governmental or judicial authority by reason of such party’s having or being deemed to have structured, drafted
or dictated such provision.

 

5.4          Complete
Agreement. This Third Amendment, together with the other Loan Documents, constitutes the complete agreement between the parties
with respect to the subject matter hereof, and supersedes any prior written or oral agreements, writings, communications or understandings
of the parties with respect thereto.

 

5.5          GOVERNING
LAW. THIS THIRD AMENDMENT SHALL BE GOVERNED BY, AND CONSTRUED AND ENFORCED IN ACCORDANCE WITH, THE LAWS OF THE STATE OF NEW
YORK APPLICABLE TO CONTRACTS MADE AND PERFORMED IN SUCH STATE.

 

5.6          Effect.
Upon the effectiveness of this Third Amendment, each reference in the Loan Agreement to “this Agreement,” “hereunder,”
“hereof” or words of like import shall mean and be a reference to the Loan Agreement as amended hereby and each reference
in the other Loan Documents to the Loan Agreement, “thereunder,” “thereof,” or words of like import shall
mean and be a reference to the Loan Agreement as amended hereby.

 

5.7          Conflict
of Terms. In the event of any inconsistency between the provisions of this Third Amendment and any provision of the Loan Agreement,
the terms and provisions of this Third Amendment shall govern and control.

 

5.8          No
Novation or Waiver. Except as specifically set forth in this Third Amendment, the execution, delivery and effectiveness of
this Third Amendment shall not (a) limit, impair, constitute a waiver by, or otherwise affect any right, power or remedy of,
Agent or Lenders under the Loan Agreement or any other Loan Document, (b) constitute a waiver of any provision in the Loan
Agreement or in any of the other Loan Documents or of any Default or Event of Default that may have occurred and be continuing,
or (c) alter, modify, amend or in any way affect any of the terms, conditions, obligations, covenants or agreements contained
in the Loan Agreement or in any of the other Loan Documents, all of which are ratified and affirmed in all respects and shall continue
in full force and effect.

 

[SIGNATURE PAGE FOLLOWS]

 

    	- 3 -

    	 

    

 

IN WITNESS WHEREOF, the parties hereto have
executed this Third Amendment to Loan and Security Agreement as of the day and year first above written.

 

	 	HORIZON CREDIT II LLC,
	 	a Delaware limited liability company, as Borrower
	 	 	 
	 	By:	/S/Robert D. Pomeroy, Jr.
	 	Name:	Robert D. Pomeroy, Jr.
	 	Title:	Chief Executive Officer
	 	 	 
	 	WELLS FARGO CAPITAL FINANCE, LLC,
	 	a Delaware limited liability company,
	 	as Agent and as a Lender
	 	 	 
	 	By:	/S/Randy Allemang
	 	Name:	Randy Allemang
	 	Title:	Vice President

 

    	- 4 -

    	 

    

 

EXHIBIT A

to

THIRD AMENDMENT TO LOAN AND SECURITY
AGREEMENT

 

    	- 5 -Exhibit
10.23

 

FIRST
AMENDMENT 

TO THE

TECHNOLOGY
LICENSE AGREEMENT

 

This First Amendment
to the Technology License Agreement dated August 23rd, 2010 by and between Baxter Healthcare SA, a Swiss corporation
having a principal place of business at Postfach, 8010, Zurich, Switzerland (hereinafter “Baxter”) and Kamada
Ltd., having a place of business at Science Park, Kiryat Weizmann, 7 Sapir St., Ness-Ziona, 74036, Israel (hereinafter “Kamada”)
(the “Agreement”) is entered into as of this 14th day of May, 2013 (the “Effective Date”). Baxter
and Kamada shall collectively be referred to as the “Parties”.

 

RECITALS

 

WHEREAS, the Parties
desire to enter into an amendment to the Agreement in order to amend the 3rd Milestone, as described hereunder and set
applicable payment schedule in connection thereto (hereinafter the "First Amendment").

 

Now
therefore, it is hereby agreed as follows:

 

		1.	The Milestone Table set forth in Section 5.3 of the Agreement
shall be replaced with the following table:

 

	Milestone	 	Milestone
    

    Payment (USD)	 
	Hand-over of [*****].	 	$	5,000,000	 
	[*****]	 	$	5,000,000	 
	Completion of transfer by [*****]	 	$	4,500,000	 
	[*****]	 	 	[*****]	 

 

		2.	The Technology Sharing Plan, which is incorporated into the Agreement as Exhibit 1.67, shall be
amended to reflect the amendment described in Section 1 above.

 

		3.	The Parties acknowledge and agree
that the 3rd Milestone has been fully achieved prior to the Effective Date. Despite the payment schedule described
in Section 5.3, the Parties agree that payment in connection with achievement of the 3rd Milestone will be made no
later than [*****], 2013.

 

 

[*****] Confidential portions of this document have been
redacted and filed separately with the Securities and Exchange Commission. 

    	First Amendment to the Technology License Agreement	Page 1

    	 

    

 

		4.	The Parties acknowledge and agree that payment for the first two (2) Milestones described in Section
5.3 has been completed in its entirety.

 

		5.	All provisions of the Agreement which are not expressly amended by the terms of this First Amendment
shall remain in effect and without change.

 

IN WITNESS WHEREOF, the Parties have caused
this First Amendment to be executed by their duly authorized representatives.

  

	BAXTER HEALTHCARE SA	 	KAMADA LTD.
	 	 	 	 	 
	By:	/s/ James Fischer	 	By:	/s/ David Tsur
	Name:	James Fischer	 	Name:  	David Tsur
	Title:	VP - EMEA Bioscience Mktg.	 	Title:  	Chief Executive Officer
	Date:	10.05.2013	 	Date:	14/5/13
	 	 	 	 	 
	By:	/s/ Yvo Aebli	 	By:	/s/ Gil Efron
	Name:	Yvo Aebli	 	Name: 	Gil Efron
	Title:	Director, Finance Baxter Healthcare SA	 	Title:  	Chief Financial Officer
	Date:	 	 	Date:	14/5/13

 

    	First Amendment to the Technology License Agreement	Page 2

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