Document:

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                                                                   Exhibit 10.14

                        COMMON STOCK PURCHASE AGREEMENT

          This COMMON STOCK PURCHASE AGREEMENT (this "Agreement") is dated as of
September __, 2001 by and between Hollis-Eden Pharmaceuticals, Inc., a Delaware
corporation (the "Company"), and Ballsbridge Finance Ltd., a Nevis corporation
(the "Purchaser").

          The parties hereto agree as follows:

                                   ARTICLE I
                                  DEFINITIONS

          Section 1.1. Certain Definitions.
                       -------------------

               (a) "Applicable Percentage" shall mean a percentage determined by
                    ---------------------
reference to the corresponding Daily Market Capitalization of the Company, in
accordance with the following table:

               Daily Market Capitalization
                     ($ in millions)                       Applicable Percentage
               ---------------------------                 ---------------------

               Less than or equal to 55                             8.5%
               More than 55 but less than or equal to 80            7.5%
               More than 80 but less than or equal to 105           6.5%
               More than 105 but less than or equal to 130          5.5%
               More than 130                                        4.5%

               (b) "Average Daily Price" shall be the price based on the VWAP of
                    -------------------
the Company on the Principal Market.

               (c) "Commencement Date" shall mean the first day of a Draw Down
                    -----------------
Pricing Period.

               (d) "Daily Market Capitalization" shall mean the Company's market
                    ---------------------------
capitalization calculated on a daily basis by multiplying the number of issued
and outstanding shares of the Company on the Trading Day preceding the
Commencement Date (without giving effect to Shares that are the subject of a
Draw Down Notice but that have not yet settled) by the VWAP on such Trading Day.

               (e) "Daily Purchase Price" shall mean the price paid per Share
                    --------------------
during each applicable Draw Down Pricing Period calculated on a daily basis and
determined by subtracting the Applicable Percentage from one and multiplying the
result by the corresponding VWAP. A pro-rata portion equal to 1/x of the Draw
Down amount (where x equals the number
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of Trading Days in the Draw Down Pricing Period) will be allocated to purchase
whole shares of Common Stock at the Daily Purchase Price for the corresponding
Trading Day.

               (f) "Draw Down" shall have the meaning assigned to such term in
                    ---------
Section 6.1(a) hereof.

               (g) "Draw Down Pricing Period" shall mean the period of five,
                    ------------------------
ten, fifteen or twenty consecutive Trading Days designated by the Company, and
beginning on the date specified, in the Draw Down Notice (as defined in Section
6.1(e) hereof); provided, however, the Draw Down Pricing Period shall not begin
                --------  -------
before the day on which receipt of such notice is deemed effective pursuant to
Section 9.4 hereof; provided, further, that if the Commencement Date is to be
the date of the Draw Down Notice, the Draw Down Notice must be delivered to and
receipt confirmed by the Purchaser at least one hour before trading commences on
such date.

               (h) "Effective Date" shall mean the date the Registration
                    --------------
Statement of the Company covering the Shares is declared effective.

               (i) "Investment Amount" shall have the meaning assigned to such
                    -----------------
term in Section 6.1(e) hereof.

               (j) "Material Adverse Effect" shall mean any adverse effect on
                    -----------------------
the business, operations, properties, prospects or financial condition of the
Company that is material and adverse to the Company and affiliates, taken as a
whole and/or any condition, circumstance, or situation that would prohibit or
otherwise materially interfere with the ability of the Company to perform any of
its material obligations under this Agreement or the Registration Rights
Agreement or to perform its material obligations under any other material
agreement; provided, however, that the following shall not be taken into account
in determining a "Material Adverse Event": (i) any adverse change, event,
effect, occurrence, state of fact or development that is directly attributable
to conditions affecting the United States economy generally unless such
conditions adversely affect the Company in a materially disproportionate manner,
(ii) any adverse change, event, effect, occurrence, state of fact or development
that is directly attributable to conditions affecting the biotechnology industry
generally, unless such conditions adversely affect the Company in a materially
disproportionate manner, (iii) any event, violation, inaccuracy, circumstance or
other matter resulting from or relating to compliance with the terms of, or the
taking of any action required by, this Agreement; provided that such event,
violation, inaccuracy, circumstance or other matter is not caused by the gross
negligence, recklessness or willful misconduct of the Company, or a default by
the Company in its obligations under this Agreement, and, (iv) operating losses
in the ordinary course of business.

               (k) "Principal Market" shall mean initially the Nasdaq National
                    ----------------
Market and shall include the Nasdaq SmallCap Market, American Stock Exchange and
the New York Stock Exchange, at such time, if any, as the Company is listed and
trades on such market or exchange. Principal Market shall not include the OTC
Bulletin Board without the written consent of the Purchaser.

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               (l) "Registration Statement" shall mean the registration
                    ----------------------
statement under the Securities Act of 1933, as amended, to be filed with the
Securities and Exchange Commission for the registration of the Shares pursuant
to the Registration Rights Agreement attached hereto as Exhibit A (the
                                                        ---------
"Registration Rights Agreement).

               (m) "SEC Documents" shall mean the Company's latest Form 10-K or
                    -------------
10-KSB as of the time in question, all Forms 10-Q or 10-QSB and 8-K filed
thereafter, and the Proxy Statement for its latest fiscal year as of the time in
question until such time as the Company no longer has an obligation to maintain
the effectiveness of a Registration Statement as set forth in the Registration
Rights Agreement.

               (n) "Settlement Period" shall have the meaning assigned to such
                    -----------------
term in Section 6.1(b).

               (o) "Shares" shall mean, collectively, the shares of Common Stock
                    ------
of the Company being subscribed for hereunder and those shares of Common Stock
issuable to the Purchaser upon exercise of the Warrants.

               (p) "Threshold Price" is the lowest Average Daily Price during
                    ---------------
any Draw Down Pricing Period at which the Company will sell its Common Stock
with respect to this Agreement.

               (q) "Trading Day" shall mean any day on which the Principal
                    -----------
Market is open for business.

               (r) "VWAP" shall mean the daily volume weighted average price of
                    ----
the Company's Common Stock on the Principal Market as reported by Bloomberg
Financial L.P. (based on a trading day from 9:30 am EST to 4:00 pm EST) using
the AQR function.

               (s) "Warrants" shall mean the Warrants as that term is defined in
                    --------
Section 5.2(f) hereof.

                                   ARTICLE II
                       PURCHASE AND SALE OF COMMON STOCK

          Section 2.1. Purchase and Sale of Stock. Subject to the terms and
                       --------------------------
conditions of this Agreement, the Company may issue and sell to the Purchaser
and the Purchaser shall purchase from the Company up to ten million dollars
($10,000,000) of the Company's Common Stock (the "Commitment Amount"), $0.01 par
value per share (the "Common Stock"), based on Draw Downs of up to two million
dollars ($2,000,000.00) per Draw Down.

          Section 2.2. The Shares. The Company has authorized and has reserved
                       ----------
and covenants to continue to reserve, free of preemptive rights and other
similar contractual rights of stockholders, a sufficient number of its
authorized but unissued shares of its Common Stock to cover the Shares to be
issued in connection with all Draw Downs requested under this

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Agreement. Anything in this Agreement to the contrary notwithstanding, (i) at no
time will the Company request a Draw Down which would result in the issuance of
an aggregate number of shares of Common Stock pursuant to this Agreement which
exceeds 19.9% of the number of shares of Common Stock issued and outstanding on
the Initial Closing Date without obtaining stockholder approval of such excess
issuance, and (ii) the Company may not make a Draw Down to the extent that,
after such purchase by the Purchaser and assuming the Purchaser does not have
beneficial ownership of any shares of Common Stock other than the Warrant
shares, the sum of the number of shares of Common Stock beneficially owned by
the Purchaser and its affiliates would result in beneficial ownership by the
Purchaser and its affiliates of more than 9.9% of the then outstanding shares of
Common Stock. For purposes of the immediately preceding sentence, beneficial
ownership shall be determined in accordance with Section 13(d) of the Securities
and Exchange Act of 1934, as amended (the "Exchange Act").

          Section 2.3. Purchase Price and Initial Closing. The Company agrees to
                       ----------------------------------
issue and sell to the Purchaser and, in consideration of and in express reliance
upon the representations, warranties and covenants of the Company and the terms
and conditions of this Agreement, the Purchaser agrees to purchase that number
of the Shares to be issued in connection with each Draw Down. The delivery of
executed documents under this Agreement and the other agreements referred to
herein and the payment of the fees set forth in Article II of the Escrow
Agreement, attached as Exhibit B hereto, (the "Initial Closing") shall take
                       ---------
place at the offices of Atlas Pearlman, P.A., 350 East Las Olas Boulevard, Suite
1700, Fort Lauderdale, Florida 33301, within fifteen (15) days from the date
hereof, or (ii) such other time and place or on such date as the Purchaser and
the Company may agree upon (the "Initial Closing Date"). Each party shall
deliver all documents, instruments and writings required to be delivered by such
party pursuant to this Agreement at or prior to the Initial Closing.

                                  ARTICLE III
                         REPRESENTATIONS AND WARRANTIES

          Section 3.1. Representation and Warranties of the Company. Except as
                       --------------------------------------------
set forth on the Schedule of Exceptions separately delivered to the Purchaser,
the Company hereby makes the following representations and warranties to the
Purchaser:

               (a) Organization, Good Standing and Power. The Company is a
                   -------------------------------------
corporation duly incorporated, validly existing and in good standing under the
laws of the State of Delaware and has all requisite corporate authority to own,
lease and operate its properties and assets and to carry on its business as now
being conducted. The Company does not have any subsidiaries and does not own
more than fifty percent (50%) of or control any other business entity except as
set forth in the SEC Documents or on Schedule 3.1(g). The Company is duly
                                     ---------------
qualified to do business and is in good standing as a foreign corporation in
every jurisdiction in which the nature of the business conducted or property
owned by it makes such qualification necessary, other than those in which the
failure so to qualify would not have a Material Adverse Effect.

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               (b) Authorization, Enforcement. (i) The Company has the requisite
                   --------------------------
corporate power and corporate authority to enter into and perform its
obligations under this Agreement, the Registration Rights Agreement, the Escrow
Agreement and to issue the Draw Down Shares pursuant to their respective terms,
(ii) the execution, issuance and delivery of this Agreement, the Registration
Rights Agreement and the Escrow Agreement by the Company and the consummation by
it of the transactions contemplated hereby and thereby have been duly authorized
by all necessary corporate action and no further consent or authorization of the
Company or its Board of Directors or stockholders is required, and (iii) this
Agreement, the Registration Rights Agreement and the Escrow Agreement have been
duly executed and delivered by the Company and at the Initial Closing shall
constitute valid and binding obligations of the Company enforceable against the
Company in accordance with their terms, except as such enforceability may be
limited by applicable bankruptcy, insolvency, reorganization, moratorium,
liquidation, conservatorship, receivership or similar laws relating to, or
affecting generally the enforcement of, creditors' rights and remedies or by
other equitable principles of general application. The Company has duly and
validly authorized and reserved for issuance shares of Common Stock sufficient
in number for the issuance of the Draw Down Shares.

               (c) Capitalization. The authorized capital stock of the Company
                   --------------
consists of 50,000,000 shares of Common Stock, $0.01 par value, of which
11,615,803 shares are issued and outstanding and 10,000,000 shares of preferred
stock, no par value, of which none are issued and outstanding. All of the
outstanding shares of the Company's Common Stock have been duly and validly
authorized and are fully paid and non-assessable, except as set forth in the SEC
Documents. Except as set forth in this Agreement and the Registration Rights
Agreement and as set forth in the SEC Documents or on Schedule 3.1(c) hereto, no
                                                      ---------------
shares of Common Stock are entitled to preemptive rights or registration rights
and there are no outstanding options, warrants, scrip, rights to subscribe to,
calls or commitments of any character whatsoever relating to, or securities or
rights convertible into, any shares of capital stock of the Company.
Furthermore, except as set forth in this Agreement and as set forth in the SEC
Documents or on Schedule 3.1(c), there are no contracts, commitments,
                ---------------
understandings, or arrangements by which the Company is or may become bound to
issue additional shares of the capital stock of the Company or options,
securities or rights convertible into shares of capital stock of the Company.
Except as set forth in Schedule 3.1(c), the Company is not a party to any
                       ---------------
agreement granting registration rights to any person with respect to any of its
equity or debt securities. Except as set forth in Schedule 3.1(c), the Company
                                                  ---------------
is not a party to, and it has no knowledge of, any agreement restricting the
voting or transfer of any shares of the capital stock of the Company. Except as
set forth in the SEC Documents or on Schedule 3.1(c) hereto, the offer and sale
                                     ---------------
of all capital stock, convertible securities, rights, warrants, or options of
the Company issued prior to the Initial Closing complied with all applicable
federal and state securities laws, and no stockholder has a right of rescission
or damages with respect thereto which would have a Material Adverse Effect on
the Company's financial condition or operating results. The Company has made
available to the Purchaser true and correct copies of the Company's Certificate
of Incorporation as in effect on the date hereof (the "Charter"), and the
Company's Bylaws as in effect on the date hereof (the "Bylaws"). The Company has
not received any notice from the Principal Market questioning or threatening the
continued inclusion of the Common Stock on such market within the past twelve
(12) months.

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               (d) Issuance of Shares. Except as set forth on Schedule 3.1(c),
                   ------------------
the Shares to be issued under this Agreement have been duly authorized by all
necessary corporate action and, when paid for or issued in accordance with the
terms hereof, the Shares shall be validly issued and outstanding, fully paid and
non-assessable, and the Purchaser shall be entitled to all rights accorded to a
holder of Common Stock.

               (e) No Conflicts. The execution, delivery and performance of this
                   ------------
Agreement by the Company and the consummation by the Company of the transactions
contemplated herein do not and will not (i) violate any provision of the
Company's Charter or Bylaws, (ii) conflict with, or constitute a default (or an
event which with notice or lapse of time or both would become a default) under,
or give to others any rights of termination, amendment, acceleration or
cancellation of, any agreement, mortgage, deed of trust, indenture, note, bond,
license, lease agreement, instrument or obligation to which the Company is a
party, (iii) create or impose a lien, charge or encumbrance on any property of
the Company under any agreement or any commitment to which the Company is a
party or by which the Company is bound or by which any of its respective
properties or assets are bound, or (iv) result in a violation of any federal,
state, local or other foreign statute, rule, regulation, order, judgment or
decree (including any federal or state securities laws and regulations)
applicable to the Company or any of its subsidiaries or by which any property or
asset of the Company or any of its subsidiaries are bound or affected, except,
in all cases, for such conflicts, defaults, termination, amendments,
accelerations, cancellations and violations as would not, individually or in the
aggregate, have a Material Adverse Effect. The business of the Company and its
subsidiaries is not being conducted in violation of any laws, ordinances or
regulations of any governmental entity, except for possible violations which
singularly or in the aggregate do not and will not have a Material Adverse
Effect. The Company is not required under any federal, state or local law, rule
or regulation to obtain any consent, authorization or order of, or make any
filing or registration with, any court or governmental agency in order for it to
execute, deliver or perform any of its obligations under this Agreement, or
issue and sell the Shares in accordance with the terms hereof (other than any
filings which may be required to be made by the Company with the Securities and
Exchange Commission (the "SEC") or state securities administrators subsequent to
the Initial Closing and any registration statement which may be filed pursuant
hereto); provided that, for purpose of the representation made in this sentence,
the Company is assuming and relying upon the accuracy of the relevant
representations and agreements of the Purchaser herein.

               (f) SEC Documents, Financial Statements. The Common Stock of the
                   -----------------------------------
Company is registered pursuant to Section 12(g) of the Securities Exchange Act
of 1934, as amended (the "Exchange Act"), and, except as disclosed in the SEC
Documents or on Schedule 3.1(f) hereto, the Company has timely filed all
                ---------------
reports, schedules, forms, statements and other documents required to be filed
by it with the SEC pursuant to the reporting requirements of the Exchange Act,
including material filed pursuant to Section 13(a) or 15(d) of the Exchange Act
(all of the foregoing including filings incorporated by reference therein being
referred to herein as the "SEC Documents"). The Company has delivered or made
available to the Purchaser true and complete copies of the SEC Documents filed
with the SEC since December 31, 1998 (which availability is deemed to have been
made to the extent such SEC Document appears in the EDGAR archives of the SEC on
the Internet. As of their respective filing dates, the SEC

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Documents complied in all material respects with the requirements of the
Exchange Act and the rules and regulations of the SEC promulgated thereunder
applicable to such documents, and, as of their respective filing dates, none of
the SEC Documents contained any untrue statement of a material fact or omitted
to state a material fact required to be stated therein or necessary in order to
make the statements therein, in light of the circumstances under which they were
made, not misleading. The financial statements of the Company included in the
SEC Documents comply as to form in all material respects with applicable
accounting requirements and the published rules and regulations of the SEC or
other applicable rules and regulations with respect thereto. Such financial
statements have been prepared in accordance with generally accepted accounting
principles ("GAAP") applied on a consistent basis during the periods involved
(except (i) as may be otherwise indicated in such financial statements or the
notes thereto or (ii) in the case of unaudited interim statements, to the extent
they may not include footnotes or may be condensed or summary statements), and
fairly present in all material respects the financial position of the Company
and its subsidiaries as of the dates thereof and the results of operations and
cash flows for the periods then ended (subject, in the case of unaudited
statements, to normal year-end audit adjustments).

               (g) Subsidiaries. The SEC Documents or Schedule 3.1(g) hereto
                   ------------
sets forth each subsidiary of the Company, showing the jurisdiction of its
incorporation or organization and showing the percentage of each person's
ownership of the outstanding stock or other interests of such subsidiary. For
the purposes of this Agreement, "subsidiary" shall mean any corporation or other
entity of which at least a majority of the securities or other ownership
interests having ordinary voting power (absolutely or contingently) for the
election of directors or other persons performing similar functions are at the
time owned directly or indirectly by the Company and/or any of its other
subsidiaries. All of the outstanding shares of capital stock of each subsidiary
have been duly authorized and validly issued, and are fully paid and
non-assessable. There are no outstanding preemptive, conversion or other rights,
options, warrants or agreements granted or issued by or binding upon any
subsidiary for the purchase or acquisition of any shares of capital stock of any
subsidiary or any other securities convertible into, exchangeable for or
evidencing the rights to subscribe for any shares of such capital stock. Neither
the Company nor any subsidiary is subject to any obligation (contingent or
otherwise) to repurchase or otherwise acquire or retire any shares of the
capital stock of any subsidiary or any convertible securities, rights, warrants
or options of the type described in the preceding sentence. Neither the Company
nor any subsidiary is a party to, nor has any knowledge of, any agreement
restricting the voting or transfer of any shares of the capital stock of any
subsidiary.

               (h) No Material Adverse Effect. Since December 31, 2000 no
                   --------------------------
Material Adverse Effect has occurred or exists with respect to the Company,
except as disclosed in the SEC Documents or on Schedule 3.1(h) hereof.

               (i) No Undisclosed Liabilities. Except as disclosed in the SEC
                   --------------------------
Documents or on Schedule 3.1(i) hereto, neither the Company nor any of its
subsidiaries has any liabilities, obligations, claims or losses (whether
liquidated or unliquidated, secured or unsecured, absolute, accrued, contingent
or otherwise) that would be required to be disclosed on a balance sheet of the
Company or any subsidiary (including the notes thereto) in conformity with GAAP
which are not disclosed in the SEC Documents, other than those incurred in the

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ordinary course of the Company's or its subsidiaries' respective businesses
since such date and which, individually or in the aggregate, do not or would not
have a Material Adverse Effect on the Company or its subsidiaries.

               (j) No Undisclosed Events or Circumstances. Since December 31,
                   --------------------------------------
2000, to the Company's knowledge no event or circumstance has occurred or exists
with respect to the Company or its businesses, properties, prospects, operations
or financial condition, that, under applicable law, rule or regulation, requires
public disclosure or announcement prior to the date hereof by the Company but
which has not been so publicly announced or disclosed in the SEC Documents.

               (k) Indebtedness. The SEC Documents or Schedule 3.1(k) hereto
                   ------------                       ---------------
sets forth as of the date hereof all outstanding secured and unsecured
Indebtedness of the Company or any subsidiary, or for which the Company or any
subsidiary has commitments. For the purposes of this Agreement, "Indebtedness"
shall mean (A) any liabilities for borrowed money or amounts owed in excess of
$250,000 (other than trade accounts payable incurred in the ordinary course of
business and payroll consistent with past practice), (B) all guaranties,
endorsements and contingent obligations in respect of Indebtedness of others,
whether or not the same are or should be reflected in the Company's balance
sheet (or the notes thereto), except guaranties by endorsement of negotiable
instruments for deposit or collection or similar transactions in the ordinary
course of business; and (C) the present value of any lease payments in excess of
$250,000 due under leases required to be capitalized in accordance with GAAP.
Neither the Company nor any subsidiary is in default with respect to any
Indebtedness.

               (l) Title to Assets. Each of the Company and the subsidiaries has
                   ---------------
good and marketable title to all of its real and personal property reflected in
the SEC Documents, free of any mortgages, pledges, charges, liens, security
interests or other encumbrances, except for those indicated in the SEC Documents
or on Schedule 3.1(1) hereto or those that would not have a Material Adverse
--------------- Effect. All said leases of the Company and each of its
subsidiaries are valid and subsisting and in full force and effect.

               (m) Actions Pending. There is no action, suit, claim,
                   ---------------
investigation or proceeding pending or, to the knowledge of the Company,
threatened against the Company or any subsidiary which questions the validity of
this Agreement or the transactions contemplated hereby or any action taken or to
be taken pursuant hereto or thereto. Except as set forth in the SEC Documents or
on Schedule 3.1(m) hereto, there is no action, suit, claim, investigation or
proceeding pending or, to the knowledge of the Company, threatened, against or
involving the Company, any subsidiary or any of their respective properties or
assets. There are no outstanding orders, judgments, injunctions, awards or
decrees of any court, arbitrator or governmental or regulatory body against the
Company or any subsidiary.

               (n) Compliance with Law. The business of the Company and the
                   -------------------
subsidiaries has been and is presently being conducted in accordance with all
applicable federal, state and local governmental laws, rules, regulations and
ordinances, except as set forth in the SEC Documents or on Schedule 3.1(n)
                                                           ---------------
hereto or such that would not cause a Material Adverse Effect. The Company and
each of its subsidiaries have all franchises, permits, licenses, consents

                                       8
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and other governmental or regulatory authorizations and approvals necessary for
the conduct of their respective businesses as now being conducted by them unless
the failure to possess such franchises, permits, licenses, consents and other
governmental or regulatory authorizations and approvals, individually or in the
aggregate, would not reasonably be expected to have a Material Adverse Effect.

               (o) Taxes. The Company and each subsidiary has filed all Tax
                   -----
Returns which it is required to file under applicable laws; all such Tax Returns
are true and accurate in all material respects and have been prepared in
compliance with all applicable laws; the Company has paid all Taxes due and
owing by it or any subsidiary (whether or not such Taxes are required to be
shown on a Tax Return) and have withheld and paid over to the appropriate taxing
authorities all Taxes which it is required to withhold from amounts paid or
owing to any employee, stockholder, creditor or other third parties; and since
December 31, 1999, the charges, accruals and reserves for Taxes with respect to
the Company (including any provisions for deferred income taxes) reflected on
the books of the Company are adequate to cover any Tax liabilities of the
Company if its current tax year were treated as ending on the date hereof.

          No claim has been made by a taxing authority in a jurisdiction where
the Company does not file tax returns that the Company or any subsidiary is or
may be subject to taxation by that jurisdiction. There are no foreign, federal,
state or local tax audits or administrative or judicial proceedings pending or
being conducted with respect to the Company or any subsidiary; no information
related to Tax matters has been requested by any foreign, federal, state or
local taxing authority; and, except as disclosed above, no written notice
indicating an intent to open an audit or other review has been received by the
Company or any subsidiary from any foreign, federal, state or local taxing
authority. There are no material unresolved questions or claims concerning the
Company's Tax liability. The Company (A) has not executed or entered into a
closing agreement pursuant to (S) 7121 of the Internal Revenue Code or any
predecessor provision thereof or any similar provision of state, local or
foreign law; and (B) has not agreed to or is required to make any adjustments
pursuant to (S) 481 (a) of the Internal Revenue Code or any similar provision of
state, local or foreign law by reason of a change in accounting method initiated
by the Company or any of its subsidiaries or has any knowledge that the IRS has
proposed any such adjustment or change in accounting method, or has any
application pending with any taxing authority requesting permission for any
changes in accounting methods that relate to the business or operations of the
Company. The Company has not been a United States real property holding
corporation within the meaning of (S) 897(c)(2) of the Internal Revenue Code
during the applicable period specified in (S) 897(c)(1)(A)(ii) of the Internal
Revenue Code.

          The Company has not made an election under (S) 341(f) of the Internal
Revenue Code. The Company is not liable for the Taxes of another person that is
not a subsidiary of the Company under (A) Treas. Reg. (S) 1.1502-6 (or
comparable provisions of state, local or foreign law), (B) as a transferee or
successor, (C) by contract or indemnity or (D) otherwise. The Company is not a
party to any tax sharing agreement. The Company has not made any payments, is
not obligated to make payments nor is it a party to an agreement that could
obligate it to make any payments that would not be deductible under (S) 280G of
the Internal Revenue Code.

                                       9
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          For purposes of this Section 3.1(o):

          "IRS" means the United States Internal Revenue Service.
           ---

          "Tax" or "Taxes" means federal, state, county, local, foreign, or
           ---      -----
other income, gross receipts, ad valorem, franchise, profits, sales or use,
transfer, registration, excise, utility, environmental, communications, real or
personal property, capital stock, license, payroll, wage or other withholding,
employment, social security, severance, stamp, occupation, alternative or add-on
minimum, estimated and other taxes of any kind whatsoever (including, without
limitation, deficiencies, penalties, additions to tax, and interest attributable
thereto) whether disputed or not.

          "Tax Return" means any return, information report or filing with
           ----------
respect to Taxes, including any schedules attached thereto and including any
amendment thereof.

               (p) Certain Fees. Except as set forth on Schedule 3.1(p) hereto,
                   ------------                         ---------------
no brokers, finders or financial advisory fees or commissions will be payable by
the Company or any subsidiary with respect to the transactions contemplated by
this Agreement.

               (q) Disclosure. To the best of the Company's knowledge, neither
                   ----------
this Agreement or the Schedules hereto nor any other documents, certificates or
instruments furnished to the Purchaser by or on behalf of the Company or any
subsidiary in connection with the transactions contemplated by this Agreement
contain any untrue statement of a material fact or omits to state a material
fact necessary in order to make the statements made herein or therein, in the
light of the circumstances under which they were made herein or therein, not
misleading.

               (r) Operation of Business. The Company operates its business
                   ---------------------
substantially in the manner set forth in the SEC Documents. The Company and each
of the subsidiaries owns or has acquired the requisite legal right to use all
patents, trademarks, service marks, trade names, copyrights, licenses and other
authorizations (collectively, "Intellectual Property") as set forth in the SEC
Documents or on Schedule 3.1(r) hereto, which are necessary for the conduct of
its business as now conducted. To the knowledge of the Company, the present
business and activities of the Company do not infringe any Intellectual Property
rights of any other person, except where such infringement would not have a
Material Adverse Effect.

               (s) Regulatory Compliance. The Company has all necessary
                   ---------------------
licenses, registrations and permits to conduct its business as now being
conducted in all states where the Company conducts its business, except where
the failure to so comply would not have a Material Adverse Effect.

               (t) Books and Records. The records and documents of the Company
                   -----------------
and its subsidiaries accurately reflect in all material respects the information
relating to the business of the Company, the location and collection of their
assets, and the nature of all transactions giving rise to the obligations or
accounts receivable of the Company.

               (u) Material Agreements. Except as set forth in the SEC Documents
                   -------------------
or on Schedule 3.1(u) hereto, neither the Company nor any subsidiary is a party
      ---------------
to any written or oral contract, instrument, agreement, commitment, obligation,
plan or arrangement, a copy of

                                       10
<PAGE>

which would be required to be filed with the SEC as an exhibit to a registration
statement on Form S-1 or other applicable form (collectively, "Material
Agreements") if the Company or any subsidiary were registering securities under
the Securities Act of 1933, as amended (the "Securities Act"). Except as set
forth in Schedule 3.1(u), the Company and each of its subsidiaries has in all
material respects performed all the obligations required to be performed by them
to date under the foregoing agreements, have received no notice of default and,
to the best of the Company's knowledge are not in default under any Material
Agreement now in effect, the result of which would cause a Material Adverse
Effect. No written or oral contract, instrument, agreement, commitment,
obligation, plan or arrangement of the Company or of any subsidiary limits or
shall limit the payment of dividends on the Company's Common Stock.

               (v) Transactions with Affiliates. Except as set forth in the SEC
                   ----------------------------
Documents or on Schedule 3.1(v) hereto, to the Company's knowledge, there are no
                ---------------
loans, leases, agreements, contracts, royalty agreements, management contracts
or arrangements or other continuing transactions exceeding $100,000 between (A)
the Company, any subsidiary or any of their respective customers or suppliers on
the one hand, and (B) on the other hand, any officer, employee, consultant or
director of the Company, or any of its subsidiaries, or any person owning any
capital stock of the Company or any subsidiary or any member of the immediate
family of such officer, employee, consultant, director or stockholder or any
corporation or other entity controlled by such officer, employee, consultant,
director or stockholder, or a member of the immediate family of such officer,
employee, consultant, director or stockholder.

               (w) Securities Laws. The Company has complied and will comply
                   ---------------
with all applicable federal and state securities laws in connection with the
offer, issuance and sale of the Shares hereunder. Neither the Company nor anyone
acting on its behalf, directly or indirectly, has or will sell, offer to sell or
solicit offers to buy the Shares or similar securities to, or solicit offers
with respect thereto from, or enter into any preliminary conversations or
negotiations relating thereto with, any person (other than the Purchaser), so as
to bring the issuance and sale of the Shares and/or Warrants under the
registration provisions of the Securities Act and applicable state securities
laws. Neither the Company nor any of its affiliates, nor any person acting on
its or their behalf, has engaged in any form of general solicitation or general
advertising (within the meaning of Regulation D under the Securities Act) in
connection with the offer or sale of the Shares.

               (x) Employees. Neither the Company nor any subsidiary has any
                   ---------
collective bargaining arrangements or agreements covering any of its employees,
except as set forth in the SEC Documents or on Schedule 3.1(x) hereto. Except as
                                               ---------------
set forth in the SEC Documents or on Schedule 3.1(x) hereto, neither the Company
                                     ---------------
nor any subsidiary is in breach of any employment contract, agreement regarding
proprietary information, noncompetition agreement, nonsolicitation agreement,
confidentiality agreement, or any other similar contract or restrictive
covenant, relating to the right of any officer, employee or consultant to be
employed or engaged by the Company or such subsidiary. Since the date of the
December 31, 2000 Form 10-K, no officer, consultant or key employee of the
Company or any subsidiary whose termination, either individually or in the
aggregate, would have a Material Adverse Effect, has terminated or, to the
knowledge of the Company, has any present intention of terminating his or her
employment or engagement with the Company or any subsidiary.

                                       11
<PAGE>

               (y) Absence of Certain Developments. Except as provided in SEC
                   -------------------------------
Documents or in Schedule 3.1(y) hereto, since December 31, 2000, neither the
                ---------------
Company nor any subsidiary has:

                   (i)     issued any stock, bonds or other corporate securities
or any rights, options or warrants with respect thereto;

                   (ii)    borrowed any amount or incurred or become subject to
any liabilities (absolute or contingent) except current liabilities incurred in
the ordinary course of business which are comparable in nature and amount to the
current liabilities incurred in the ordinary course of business during the
comparable portion of its prior fiscal year, as adjusted to reflect the current
nature and volume of the Company's or such subsidiary's business;

                   (iii)   discharged or satisfied any lien or encumbrance or
paid any obligation or liability (absolute or contingent), other than current
liabilities paid in the ordinary course of business;

                   (iv)    declared or made any payment or distribution of cash
or other property to stockholders with respect to its stock, or purchased or
redeemed, or made any agreements so to purchase or redeem, any shares of its
capital stock;

                   (v)     sold, assigned or transferred any other tangible
assets, or canceled any debts or claims, except in the ordinary course of
business;

                   (vi)    sold, assigned or transferred any patent rights,
trademarks, trade names, copyrights, trade secrets or other intangible assets or
intellectual property rights;

                   (vii)   suffered any substantial losses or waived any rights
of material value, whether or not in the ordinary course of business;

                   (viii)  made any changes in employee compensation except in
the ordinary course of business and consistent with past practices;

                   (ix)    made capital expenditures or commitments therefor
that aggregate in excess of $500,000;

                   (x)     entered into any other material transaction, whether
or not in the ordinary course of business;

                   (xi)    suffered any material damage, destruction or casualty
loss, whether or not covered by insurance; or

                   (xii)   experienced any material problems with labor or
management in connection with the terms and conditions of their employment;

                                       12
<PAGE>

               (z) Governmental Approvals. Except as set forth in the SEC
                   ----------------------
Documents or on Schedule 3.1(z) hereto, and except for the filing of any notice
                ---------------
prior or subsequent to the Closing that may be required under applicable federal
or state securities laws (which if required, shall be filed on a timely basis),
including the filing of a registration statement or statements pursuant to this
Agreement, no authorization, consent, approval, license, exemption of, filing or
registration with any court or governmental department, commission, board,
bureau, agency or instrumentality, domestic or foreign, is or will be necessary
for, or in connection with, the execution or delivery of the Shares, or for the
performance by the Company of its obligations under this Agreement.

               (aa) Use of Proceeds. The proceeds from the sale of the Shares
                    ---------------
will be used by the Company and its subsidiaries for general corporate purposes.

               (bb) Acknowledgment Regarding Purchaser's Purchase of Shares. The
                    -------------------------------------------------------
Company acknowledges and agrees that Purchaser is acting solely in the capacity
of arm's length purchaser with respect to this Agreement and the transactions
contemplated hereunder.  The Company further acknowledges that the Purchaser is
not acting as a financial advisor or fiduciary of the Company (or in any similar
capacity) with respect to this Agreement and the transactions contemplated
hereunder and any advice given by the Purchaser or any of its representatives or
agents in connection with this Agreement and the transactions contemplated
hereunder is merely incidental to the Purchaser's purchase of the Shares.  The
Company further represents to the Purchaser that the Company's decision to enter
into this Agreement has been based solely on the independent evaluation by the
Company and its own representatives and counsel.

          Section 3.2. Representations and Warranties of the Purchaser. The
                       -----------------------------------------------
Purchaser hereby makes the following representations and warranties to the
Company:

               (a) Organization and Standing of the Purchaser. The Purchaser is
                   ------------------------------------------
a corporation duly incorporated, validly existing and in good standing under the
laws of Nevis.

               (b) Authorization and Power. The Purchaser has the requisite
                   -----------------------
power and authority to enter into and perform this Agreement and to purchase the
Shares being sold to it hereunder. The execution, delivery and performance of
this Agreement by Purchaser and the consummation by it of the transactions
contemplated hereby have been duly authorized by all necessary corporate action.

               (c) No Conflicts. The execution, delivery and performance of this
                   ------------
Agreement and the consummation by the Purchaser of the transactions contemplated
hereby or relating hereto do not and will not (i) result in a violation of such
Purchaser's Charter or Bylaws or (ii) conflict with, or constitute a default (or
an event which with notice or lapse of time or both would become a default)
under, or give to others any rights of termination, amendment, acceleration or
cancellation of any agreement, indenture or instrument to which the Purchaser is
a party, or result in a violation of any law, rule, or regulation, or any order,
judgment or decree of any court or governmental agency applicable to the
Purchaser or its properties (except for such conflicts, defaults and violations
as would not, individually or in the aggregate, have a Material Adverse Effect
on Purchaser). The Purchaser is not required to obtain any consent,
authorization

                                       13
<PAGE>

or order of, or make any filing or registration with, any court or governmental
agency in order for it to execute, deliver or perform any of its obligations
under this Agreement or to purchase the Shares in accordance with the terms
hereof, provided that for purposes of the representation made in this sentence,
the Purchaser is assuming and relying upon the accuracy of the relevant
representations and agreements of the Company herein.

               (d) Financial Risks. The Purchaser acknowledges that it is able
                   ---------------
to bear the financial risks associated with an investment in the Shares and that
it has been given full access to such records of the Company and the
subsidiaries and to the officers of the Company and the subsidiaries as it has
deemed necessary or appropriate to conduct its due diligence investigation. The
Purchaser is capable of evaluating the risks and merits of an investment in the
Shares by virtue of its experience as an investor and its knowledge, experience,
and sophistication in financial and business matters and the Purchaser is
capable of bearing the entire loss of its investment in the Shares.

               (e) Accredited Investor. The Purchaser is an "accredited
                   -------------------
investor" as defined in Regulation D promulgated under the Securities Act.

               (f) Compliance With Law. The Purchaser's trading and distribution
                   -------------------
activities with respect to the Shares will be in compliance with all applicable
state and federal securities laws, rules and regulations and the rules and
regulations of the Principal Market.

               (g) General. The Purchaser understands that the Company is
                   -------
relying upon the truth and accuracy of the representations, warranties,
agreements, acknowledgments and understandings of the Purchaser set forth herein
in order to determine the suitability of the Purchaser to acquire the Shares.

                                   ARTICLE IV
                                   COVENANTS

          The Company covenants with the Purchaser as follows:

          Section 4.1  Securities Compliance.  If applicable, the Company shall
                       ---------------------
notify the Principal Market, in accordance with their rules and regulations, of
the transactions contemplated by this Agreement, and shall take all other
necessary action and proceedings as may be required and permitted by applicable
law, rule and regulation, for the legal and valid issuance of the Shares and the
Warrants to the Purchaser or subsequent holders.

          Section 4.2  Registration and Listing.  The Company will cause its
                       ------------------------
Common Stock to continue to be registered under Sections 12(b) or 12(g) of the
Exchange Act, will comply in all respects with its reporting and filing
obligations under the Exchange Act, will comply with all requirements related to
any registration statement filed pursuant to this Agreement, and will not take
any action or file any document (whether or not permitted by the Securities Act
or the rules promulgated thereunder) to terminate or suspend such registration
or to terminate or suspend its reporting and filing obligations under the
Exchange Act or Securities

                                       14
<PAGE>

Act, except as permitted herein. The Company will take all commercially
reasonable action necessary to continue the listing or trading of its Common
Stock on the Principal Market and will comply in all respects with the Company's
reporting, filing and other obligations under the bylaws or rules of the
Principal Market and shall provide the Purchasers with copies of any
correspondence to or from such Principal Market which questions or threatens
delisting of the Common Stock, within three (3) Trading Days of the Company's
receipt thereof, until the Purchasers have disposed of all of their Registrable
Securities.

          Section 4.3  Registration Statement.  The Company shall cause to be
                       ----------------------
filed the Registration Statement, which Registration Statement shall provide for
the resale of the Shares by the Purchaser to the public in accordance with this
Agreement.  The Purchaser shall not be obligated to accept a Draw Down request
from the Company, unless the Registration Statement is effective and the
prospectus included in the Registration Statement is current.

          Section 4.4  Escrow Arrangement.  The Company and the Purchaser shall
                       ------------------
enter into an escrow arrangement with Atlas Pearlman, P.A. (the "Escrow Agent")
in the Form of Exhibit B hereto respecting payment against delivery of the
               ---------
Shares.

          Section 4.5  Registration Rights Agreement.  The Company and the
                       -----------------------------
Purchaser shall enter into the Registration Rights Agreement in the Form of
Exhibit A hereto.
---------

          Section 4.6  Compliance with Laws.  The Company shall comply, and
                       --------------------
cause each subsidiary to comply, with all applicable laws, rules, regulations
and orders, noncompliance with which could have a Material Adverse Effect.

          Section 4.7  Keeping of Records and Books of Account.  The Company
                       ---------------------------------------
shall keep and cause each subsidiary to keep adequate records and books of
account, in which complete entries will be made in accordance with GAAP
consistently applied, reflecting all financial transactions of the Company and
its subsidiaries, and in which, for each fiscal year, all proper reserves for
depreciation, depletion, obsolescence, amortization, taxes, bad debts and other
purposes in connection with its business shall be made.

          Section 4.8  Consolidation; Merger.  The Company shall not, at any
                       ---------------------
time after the date hereof, effect any merger or consolidation of the Company
with or into, or a transfer of all or substantially all of the assets of the
Company to, another entity (a "Consolidation Event") unless the resulting
successor or acquiring entity (if not the Company) assumes by written instrument
or by operation of law the obligations to the Purchaser under this Agreement.

          Section 4.9  Limitation on Future Financing.  The Company agrees that
                       ------------------------------
it will not enter into any sale of its securities in an equity line financing or
substantial equivalent until the earlier of (i) 18 months from the effective
date of the Registration Statement or (ii) sixty (60) days after the entire
$10,000,000 of Common Stock has been purchased by the Purchaser.  For purposes
hereof, an "equity line financing or substantial equivalent" shall mean equity
line financings similar in scope to the financing contemplated hereby, wherein
the Company has the right to "put" its securities to an investor, at the
Company's sole discretion, at a purchase price calculated pursuant to a formula
that applies a discount to the market price for the Company's

                                       15
<PAGE>

Common Stock, but shall not include securities issued in connection with
strategic partnerships, acquisitions, trade financings, underwritten public
offerings or employee compensation arrangements. Subject to the foregoing,
nothing herein shall be construed to limit the Company's right to enter into any
financing or other arrangement or agreement. The limitation contained in the
first sentence of this paragraph shall not apply in the case of a Consolidation
Event to the extent that the acquiror is a bona fide party to an equity line
financing or substantial equivalent on the effective date of such Consolidation
Event.

          The Purchaser covenants with the Company as follows:

          Section 4.10  Compliance with Law.  The Purchaser's trading activities
                        -------------------
with respect to shares of the Company's Common Stock will be in compliance with
all applicable state and federal securities laws, rules and regulations and
rules and regulations of the Principal Market on which the Company's Common
Stock is listed.  Without limiting the generality of the foregoing, the
Purchaser agrees that it will, whenever required by federal securities laws,
deliver the prospectus included in the Registration Statement to any purchaser
of Shares from the Purchaser.

          Section 4.11  Securities Transactions. During the term of this
                        -----------------------
Agreement, the Purchaser, together with its affiliates, will never be in a "net
short" position with respect to the Company's Common Stock.

                                   ARTICLE V
                  CONDITIONS TO INITIAL CLOSING AND DRAW DOWNS

          Section 5.1. Conditions Precedent to the Obligation of the Company to
                       ---------------------------------------------------------
Sell the Shares. The obligation hereunder of the Company to issue and sell the
---------------
Shares to the Purchaser is subject to the satisfaction or waiver, at or before
the Initial Closing, and as of each Settlement Date of each of the conditions
set forth below. These conditions are for the Company's sole benefit and may be
waived by the Company at any time in its sole discretion.

               (a) Accuracy of the Purchaser's Representations and Warranties.
                   ----------------------------------------------------------
The representations and warranties of the Purchaser shall be true and correct in
all material respects as of the date when made and as of the Initial Closing and
as of each Settlement Date as though made at that time, except for
representations and warranties that speak as of a particular date.

               (b) Performance by the Purchaser. The Purchaser shall have
                   ----------------------------
performed, satisfied and complied in all material respects with all material
covenants, agreements and conditions required by this Agreement to be performed,
satisfied or complied with by the Purchaser at or prior to the Initial Closing
and as of each Settlement Date.

               (c) No Injunction. No statute, rule, regulation, executive order,
                   -------------
decree, ruling or injunction shall have been enacted, entered, promulgated or
endorsed by any court or governmental authority of competent jurisdiction which
prohibits the consummation of any of the transactions contemplated by this
Agreement.

                                       16
<PAGE>

          Section 5.2. Conditions Precedent to the Obligation of the Purchaser
                       --------------------------------------------------------
to Close. The obligation hereunder of the Purchaser to perform its obligations
--------
under this Agreement and to purchase the Shares is subject to the satisfaction
or waiver, at or before the Initial Closing, of each of the conditions set forth
below. These conditions are for the Purchaser's sole benefit and may be waived
by the Purchaser at any time prior to the Initial Closing in its sole
discretion.

               (a) Accuracy of the Company's Representations and Warranties.
                   --------------------------------------------------------
Each of the representations and warranties of the Company shall be true and
correct in all material respects as of the date when made and as of the Initial
Closing as though made at that time (except for representations and warranties
that speak as of a particular date).

               (b) Performance by the Company. The Company shall have performed,
                   --------------------------
satisfied and complied in all respects with all covenants, agreements and
conditions required by this Agreement to be performed, satisfied or complied
with by the Company at or prior to the Initial Closing.

               (c) No Injunction. No statute, rule, regulation, executive order,
                   -------------
decree, ruling or injunction shall have been enacted, entered, promulgated or
endorsed by any court or governmental authority of competent jurisdiction which
prohibits the consummation of any of the transactions contemplated by this
Agreement.

               (d) No Proceedings or Litigation. No action, suit or proceeding
                   -----------------------------
before any arbitrator or any governmental authority shall have been commenced,
and no investigation by any governmental authority shall have been threatened,
against the Purchaser or the Company or any subsidiary, or any of the officers,
directors or affiliates of the Company or any subsidiary seeking to restrain,
prevent or change the transactions contemplated by this Agreement, or seeking
damages in connection with such transactions.

               (e) Opinion of Counsel, Etc. At the Initial Closing, the
                   -----------------------
Purchaser shall have received an opinion of outside counsel to the Company,
dated the date of the Initial Closing, in the form of Exhibit C hereto, and such
other certificates as the Purchaser may reasonably request.

               (f) Commitment Fee. The Purchaser shall receive a commitment fee
                   --------------
payable by the Company's delivery to the Purchaser or its designee(s) of common
stock purchase warrants (the "Warrants"). The Warrants, which shall be issued
and delivered at the Initial Closing, shall entitle the holder to acquire common
stock of the Company based upon 5,000 Warrants for each $1,000,000 of the
Commitment Amount not Drawn Down by the Company. The Warrants may be exercised
at any time during the three (3) years commencing on the first day following
expiration of the Commitment Period. The exercise price of the Warrants shall be
100% of the Average Daily Price on the Trading Day immediately prior to the last
day of the Commitment Period. The Common Stock underlying the Warrants will be
registered in the Registration Statement referred to in Section 4.3 hereof. The
Warrants shall be in the form of Exhibit E hereto.
                                 ---------

                                       17
<PAGE>

          Section 5.3. Conditions Precedent to the Obligation of the Purchaser
                       --------------------------------------------------------
to Accept a Draw Down and Purchase the Shares. The obligation hereunder of the
---------------------------------------------
Purchaser to accept a Draw Down request and to acquire and pay for the Shares is
subject to the satisfaction at or before each Settlement Date, of each of the
conditions set forth below.

               (a) Satisfaction of Conditions to Initial Closing. The Company
                   ---------------------------------------------
shall have satisfied, or the Purchaser shall have waived, at or prior to the
Initial Closing, the conditions set forth in Section 5.2 hereof

               (b) Effective Registration Statement. The Registration Statement
                   --------------------------------
registering the Shares shall have been declared effective by the SEC and shall
remain effective on such Settlement Date.

               (c) No Suspension. Trading in the Company's Common Stock shall
                   -------------
not have been suspended by the SEC or the Principal Market (except for any
suspension of trading of limited duration agreed to by the Company, which
suspension shall be terminated prior to the delivery of each Draw Down Notice),
and, at any time prior to such Draw Down Notice, trading in securities generally
as reported on the Principal Market shall not have been suspended or limited.

               (d) Material Adverse Effect. No Material Adverse Effect and no
                   -----------------------
Consolidation Event where the successor entity has not agreed to perform the
Company's obligations shall have occurred.

               (e) Opinion of Counsel. The Purchaser shall have received a
                   ------------------
"down-to-date" letter from the Company's outside counsel, confirming that there
is no change from the counsel's previously delivered opinion, or else specifying
with particularity the reason for any change; provided, however, that no
"down-to-date" opinion of outside counsel shall be required to the extent that
such an opinion has been delivered to the Purchaser within thirty (30) days
prior to the applicable Settlement Date.

                                   ARTICLE VI
                                DRAW DOWN TERMS

          Section 6.1. Draw Down Terms. Subject to the satisfaction of the
                       ---------------
conditions set forth in this Agreement, the parties agree as follows:

               (a) The Company, may, in its sole discretion, issue and exercise
a draw down (a "Draw Down") during each Draw Down Pricing Period, which Draw
Down the Purchaser will be obligated to accept for a period of 18 months
commencing immediately after the Effective Date (the "Commitment Period").
Subject to the terms and conditions hereof, the Company may issue and exercise
an unlimited number of Draw Downs during the Commitment Period.

                                       18
<PAGE>

               (b)  Only one Draw Down shall be allowed in each Draw Down
Pricing Period. The number of shares of Common Stock purchased by the Purchaser
with respect to each Draw Down shall be determined as set forth in Section
6.1(d) herein and settled (i) as to the 1/st/ through the 5/th/ Trading Days
after the applicable Commencement Date (the "First Settlement Period"), on the
7/th/ Trading Day after such Commencement Date and (ii) as to the 6/th/ through
the 10/th/ Trading Days after the applicable Commencement Date (the "Second
Settlement Period"), on the 12/th/ Trading Day after such Commencement Date,
(iii) as to the 11/th/ through the 15/th/ Trading Days after the applicable
Commencement Date (the "Third Settlement Period"), on the 17/th/ Trading Day
after such Commencement Date and (iv) as to the 16/th/ through the 20/th/
Trading Days after the applicable Commencement Date (the "Fourth Settlement
Period"), on the 22/nd/ Trading Day after such Commencement Date (each, a
"Settlement Date" and the First, Second, Third and Fourth Settlement Periods
collectively referred to as "Settlement Periods"). In connection with each Draw
Down Pricing Period, the Company may set the Threshold Price. If the Average
Daily Price on any day within the Draw Down Pricing Period is less than the
Threshold Price, the Company shall not sell and the Purchaser shall not be
obligated to purchase the Shares otherwise to be purchased for such day. A pro-
rata portion equal to 1/x of the Draw Down amount (where x equals the number of
Trading Days in the Draw Down Pricing Period) will be allocated to purchase
whole shares of Common Stock at the Daily Purchase Price for the corresponding
Trading Day.

               (c)  The minimum Investment Amount shall be $100,000 and the
maximum Investment Amount shall be $2,000,000; provided, however, the maximum
                                               --------  -------
Investment Amount during any Draw Down Pricing Period shall not be greater than
the product obtained by multiplying (i) the average daily trading volume for the
Company's Common Stock on the Principal Market, for the number of consecutive
Trading Days as is equal to the number of days in the Draw Down Notice (the
"Trading Day Measurement Period"), ending on the day prior to the Draw Down
Notice, times (ii) the number of trading days in the Draw Down Pricing Period,
times (iii) the average VWAP during the Trading Day Measurement Period, times
(iv) twenty percent (20%).

               (d)  The number of Shares of Common Stock to be issued on each
Settlement Date shall be a number of shares equal to (for each Trading Day
within the Settlement Period) (x) 1/x of the Investment Amount, divided by (y)
the Daily Purchase Price on each Trading Day within the Settlement Period,
subject to the following adjustments:

                    (i)   if the Average Daily Price on a given Trading Day is
less than the Threshold Price, then the Investment Amount will be reduced by 1/x
and that day shall be withdrawn from the Settlement Period;

                    (ii)  if trading of the Common Stock on the Principal Market
is suspended for more than three (3) hours, in the aggregate, on any Trading Day
during the Settlement Period, the Investment Amount shall be reduced by 1/x and
that day shall be withdrawn from the applicable Settlement Period; and

                    (iii) if the trading volume for the Common Stock on the
Principal Market on any Trading Day is less than fifty percent (50%) of the
rolling average

                                       19
<PAGE>

trading volume for the immediately preceding twenty (20) consecutive Trading
Days, the Investment Amount shall be reduced by 1/x and that day shall be
withdrawn from the applicable Settlement Period.

               (e)  The Company must inform the Purchaser by delivering before
the Commencement Date a draw down notice, in the form of Exhibit D hereto (the
                                                         ---------
"Draw Down Notice"), via facsimile transmission in accordance with Section 9.4
as to the amount of the Draw Down (the "Investment Amount") the Company wishes
to exercise. If the Commencement Date is to be the date of the Draw Down Notice,
the Draw Down Notice must be delivered to and receipt confirmed by the Purchaser
at least one hour before trading commences on such date. The Company may not
deliver a new Draw Down Notice until the third Trading Day following the final
Settlement Date for the preceding Draw Down Pricing Period. At no time shall the
Purchaser be required to purchase more than the maximum Draw Down amount for a
given Draw Down Pricing Period so that if the Company chooses not to exercise
the maximum permitted Draw Down in a given Draw Down Pricing Period the
Purchaser is not obligated to and shall not purchase more than the scheduled
maximum amount in a subsequent Draw Down Pricing Period.

               (f)  On the Trading Day following the end of each Settlement
Period (i) the Company and the Purchaser shall each execute and deliver to the
other and to the Escrow Agent via facsimile transmission, a settlement
certificate in the form of Exhibit E hereto (the "Settlement Certificate")
                           ---------
quantifying the amount of the Draw Down and the number of shares of Common Stock
to be purchased, (ii) the Company will file a prospectus supplement to the
prospectus forming a part of the Registration Statement and deliver a copy of
the prospectus and prospectus supplement to the Purchaser prior to the release
of funds by the Escrow Agent, (iii) the Company shall cause the delivery of that
number of whole shares of Common Stock of the Company designated in the
Settlement Certificate (the "Settlement Shares") , via DWAC, to an account
designated by the Escrow Agent in the Escrow Agreement, and (iv) the Purchaser
shall transmit payment in an amount equal to the payment designated in the
Settlement Certificate (the "Settlement Payment"), to the Escrow Agent, via wire
transfer to the coordinates specified by the Escrow Agent in the Escrow
Agreement.

               (g)  On the Settlement Date, and provided that the provisions of
Section 6.1(f) have been complied with (i) the Escrow Agent shall transmit the
Settlement Payment to the Company, via wire transfer to the coordinates
specified by the Company in the Escrow Agreement and (ii) the Escrow Agent shall
cause the delivery of the Settlement Shares to the Purchaser, via DWAC, to the
account specified by the Purchaser in the Escrow Agreement. Notwithstanding the
foregoing, in the event the Settlement Shares are not received by the Escrow
Agent on or prior to 12:00 noon on the Settlement Date, transmission of the
Settlement Payment to the Company will be made by next day available funds.
Prior to transmission of the Settlement Payment to the Company, the Escrow Agent
shall deduct its fee of one thousand dollars ($1,000). The process of delivery
of the Shares against payment therefor is herein referred to as "Settlement".

               (h)  In the event the Company fails to deliver the Shares of
Common Stock purchased by the Purchaser within five (5) business days of the
applicable Settlement Date, then (i) the Company shall pay to the Purchaser or
its designee(s), in cash or restricted shares of

                                       20
<PAGE>

the Company's Common Stock, at the option of the Company, as liquidated damages
and not as a penalty, an amount equal to two percent (2%) of the Draw Down
amount for the initial thirty (30) day period in which such failure occurs, and
a pro-rated amount for each thirty (30) day period thereafter until such failure
has been cured, and (ii) the Purchaser shall not be obligated to purchase any
additional shares of Common Stock for the remainder of the applicable Draw Down
Pricing Period.

                                  ARTICLE VII
                                  TERMINATION

          Section 7.1.  Termination. The term of this Agreement shall be
                        -----------
eighteen (18) months from the Effective Date.

          Section 7.2.  Other Termination.
                        -----------------

               (a)  The Purchaser may terminate this Agreement upon one (1)
Trading Day's notice if (i) an event resulting in a Material Adverse Effect has
occurred and has not been cured for a period of 60 days, (ii) the Common Stock
is de-listed from the Principal Market unless such de-listing is in connection
with the listing of the Common Stock on the Nasdaq National Market, Nasdaq
SmallCap Market, the American Stock Exchange or the New York Stock Exchange or
(iii) the Company files for protection from creditors under any applicable law.

               (b)  The Company may terminate this Agreement upon one (1)
Trading Day's notice if the Purchaser shall fail to fund a properly noticed Draw
Down within three (3) Trading Days of a Settlement Date.

          Section 7.3.  Effect of Termination.  In the event of termination by
                        ---------------------
the Company or the Purchaser, written notice thereof shall forthwith be given to
the other party and the transactions contemplated by this Agreement shall be
terminated without further action by either party. If this Agreement is
terminated as provided in Section 7.1 or 7.2 herein, this Agreement shall become
void and of no further force and effect, except for Sections 9.1 and 9.2, and
Article VIII herein. Nothing in this Section 7.3 shall be deemed to release the
Company or the Purchaser from any liability for any breach under this Agreement,
or to impair the rights of the Company and the Purchaser to compel specific
performance by the other party of its obligations under this Agreement.

                                 ARTICLE VIII
                                INDEMNIFICATION

          Section 8.1.  General Indemnity.  The Company agrees to indemnify and
                        -----------------
hold harmless the Purchaser (and its directors, officers, affiliates, agents,
successors and assigns) from and against any and all losses, liabilities,
deficiencies, costs, damages and expenses (including, without limitation,
reasonable attorney's fees, charges and disbursements) incurred by the Purchaser
as a result of any inaccuracy in or breach of the representations, warranties or
covenants made by the Company herein. The Purchaser agrees to indemnify and hold
harmless

                                       21
<PAGE>

the Company and its directors, officers, affiliates, agents, successors and
assigns from and against any and all losses, liabilities, deficiencies, costs,
damages and expenses (including, without limitation, reasonable attorneys fees,
charges and disbursements) incurred by the Company as result of any inaccuracy
in or breach of the representations, warranties or covenants made by the
Purchaser herein. Notwithstanding anything to the contrary herein, the Purchaser
shall be liable under this Section 8.1 for only that amount as does not exceed
the net proceeds to such Purchaser as a result of the sale of Shares pursuant to
the Registration Statement.

          Section 8.2.  Indemnification Procedure.  Any party entitled to
                        -------------------------
indemnification under this Article VIII (an "Indemnified Party") will give
written notice to the indemnifying party of any matters giving rise to a claim
for indemnification; provided, that the failure of any party entitled to
indemnification hereunder to give notice as provided herein shall not relieve
the indemnifying party of its obligations under this Article VIII except to the
extent that the indemnifying party is actually prejudiced by such failure to
give notice. In case any action, proceeding or claim is brought against an
Indemnified Party in respect of which indemnification is sought hereunder, the
indemnifying party shall be entitled to participate in and, unless in the
reasonable judgment of counsel to the Indemnified Party a conflict of interest
between it and the indemnifying party may exist with respect of such action,
proceeding or claim, to assume the defense thereof with counsel reasonably
satisfactory to the Indemnified Party. In the event that the indemnifying party
advises an Indemnified Party that it will contest such a claim for
indemnification hereunder, or fails, within thirty (30) days of receipt of any
indemnification notice to notify, in writing, such person of its election to
defend, settle or compromise, at its sole cost and expense, any action,
proceeding or claim (or discontinues its defense at any time after it commences
such defense), then the Indemnified Party may, at its option, defend, settle or
otherwise compromise or pay such action or claim. In any event, unless and until
the indemnifying party elects in writing to assume and does so assume the
defense of any such claim, proceeding or action, the Indemnified Party's costs
and expenses arising out of the defense, settlement or compromise of any such
action, claim or proceeding shall be losses subject to indemnification
hereunder. The Indemnified Party shall cooperate fully with the indemnifying
party in connection with any settlement negotiations or defense of any such
action or claim by the indemnifying party and shall furnish to the indemnifying
party all information reasonably available to the Indemnified Party, which
relates to such action or claim. The indemnifying party shall keep the
Indemnified Party fully apprised at all times as to the status of the defense or
any settlement negotiations with respect thereto. If the indemnifying party
elects to defend any such action or claim, then the Indemnified Party shall be
entitled to participate in such defense with counsel of its choice at its sole
cost and expense. The indemnifying party shall not be liable for any settlement
of any action, claim or proceeding effected without its prior written consent.
Notwithstanding anything in this Article VIII to the contrary, the indemnifying
party shall not, without the Indemnified Party's prior written consent, settle
or compromise any claim or consent to entry of any judgment in respect thereof
which imposes any future obligation on the Indemnified Party or which does not
include, as an unconditional term thereof, the giving by the claimant or the
plaintiff to the Indemnified Party of a release from all liability in respect of
such claim. The indemnification required by this Article VIII shall be made by
periodic payments of the amount thereof during the course of investigation or
defense, as and when bills are received or expense, loss, damage or liability is
incurred, within ten (10) Trading Days of written notice

                                       22
<PAGE>

thereof to the indemnifying party so long as the Indemnified Party irrevocably
agrees to refund such moneys if it is ultimately determined by a court of
competent jurisdiction that such party was not entitled to indemnification. The
indemnity agreements contained herein shall be in addition to (a) any cause of
action or similar rights of the Indemnified Party against the indemnifying party
or others, and (b) any liabilities the indemnifying party may be subject to.

                                  ARTICLE IX
                                 MISCELLANEOUS

          Section 9.1.  Fees and Expenses.  The Company shall pay all fees and
                        -----------------
expenses related to the transactions contemplated by this Agreement, other than
legal fees and expenses of the Purchaser; provided, that, upon execution of this
Agreement, the Company shall pay all attorneys fees and expenses (inclusive of
disbursements and out-of-pocket expenses) incurred by the Purchaser of $35,000
in connection with the preparation, negotiation, execution and delivery of this
Agreement and the transactions contemplated hereunder, the receipt of $5,000 of
which is hereby acknowledged. The Company shall pay all stamp or other similar
taxes and duties levied in connection with issuance of the Shares pursuant
hereto.

          Section 9.2.  Specific Enforcement.  The Company and the Purchaser
                        --------------------
acknowledge and agree that irreparable damage would occur in the event that any
of the provisions of this Agreement were not performed in accordance with their
specific terms or were otherwise breached. It is accordingly agreed that the
parties shall be entitled to an injunction or injunctions to prevent or cure
breaches of the provisions of this Agreement and to enforce specifically the
terms and provisions hereof or thereof, this being in addition to any other
remedy to which any of them may be entitled by law or equity.

          Section 9.3.  Entire Agreement; Amendment.  This Agreement, together
                         --------------------------
with the Registration Rights Agreement and the Escrow Agreement contains the
entire understanding of the parties with respect to the matters covered hereby
and, except as specifically set forth herein, neither the Company nor the
Purchaser makes any representations, warranty, covenant or undertaking with
respect to such matters. No provision of this Agreement may be waived or amended
other than by a written instrument signed by the party against whom enforcement
of any such amendment or waiver is sought.

          Section 9.4.  Notices.  Any notice, demand, request, waiver or other
                        -------
communication required or permitted to be given hereunder shall be in writing
and shall be effective (a) upon hand delivery or facsimile at the address or
number designated below (if delivered on a business day during normal business
hours where such notice is to be received), or the first business day following
such delivery (if delivered other than on a business day during normal business
hours where such notice is to be received) or (b) on the second business day
following the date of mailing by express courier service, fully prepaid,
addressed to such address, or upon actual receipt of such mailing, whichever
shall first occur.  The addresses for such communications shall be:

                                       23
<PAGE>

If to the Company:       Hollis-Eden Pharmaceuticals, Inc.
                         9333 Genesee Avenue
                         Suite 200
                         San Diego, CA 92121
                         Attn: Daniel Burgess, CFO
                         and Eric Loumeau, General Counsel
                         Tel: (858) 587-9333
                         Fax: (858) 587-0896

With copies to:          Cooley Godward LLP
                         4365 Executive Drive
                         Suite 1100
                         San Diego, CA 92121
                         Attn: Thomas A. Coll, Esq.
                         Tel: (858) 550-6013
                         Fax: (858) 453-3555

If to the Purchaser:     Ballsbridge Finance Ltd.
                         38 Hertford Street
                         London W1Y 7TG United Kingdom
                         Attn: Mr. James Martin
                         Tel: 011-44-207-355-2051
                         Fax: 011-44-207-355-4975

with copies to:          Atlas Pearlman, P.A.
                         350 East Las Olas Boulevard
                         Suite 1700
                         Fort Lauderdale, FL 33301
                         Attn: James M. Schneider, Esq.
                         Tel: (954) 763-1200
                         Fax: (954) 766-7800

          Any party hereto may from time to time change its address for notices
by giving written notice of such changed address to the other party hereto in
accordance herewith.

          Section 9.5.  Waivers.  No waiver by either party of any default with
                        -------
respect to any provision, condition or requirement of this Agreement shall be
deemed to be a continuing waiver in the future or a waiver of any other
provisions, condition or requirement hereof, nor shall any delay or omission of
any party to exercise any right hereunder in any manner impair the exercise of
any such right accruing to it thereafter.

          Section 9.6.  Headings.  The article, section and subsection headings
                        --------
in this Agreement are for convenience only and shall not constitute a part of
this Agreement for any other purpose and shall not be deemed to limit or affect
any of the provisions hereof.

                                       24
<PAGE>

          Section 9.7.  Successors and Assigns.  This Agreement shall be binding
                        ----------------------
upon and inure to the benefit of the parties and their successors and assigns.
The parties hereto may not amend this Agreement or any rights or obligations
hereunder without the prior written consent of the Company and each Purchaser to
be affected by the amendment. After the Initial Closing, the assignment by a
party to this Agreement of any rights hereunder shall not affect the obligations
of such party under this Agreement.

          Section 9.8.  No Third Party Beneficiaries. This Agreement is intended
                        ----------------------------
for the benefit of the parties hereto and their respective permitted successors
and assigns and is not for the benefit of, nor may any provision hereof be
enforced by, any other person.

          Section 9.9.  Governing Law/Arbitration. This Agreement shall be
                        -------------------------
governed by and construed in accordance with the internal laws of the State of
California, without giving effect to the choice of law provisions. Any dispute
under this Agreement or any Exhibit attached hereto shall be submitted to
arbitration under the American Arbitration Association (the "AAA") in New York
City, New York, and shall be finally and conclusively determined by the decision
of a board of arbitration consisting of three (3) members (hereinafter referred
to as the "Board of Arbitration") selected as according to the rules governing
the AAA. The Board of Arbitration shall meet on consecutive business days in New
York City, New York, and shall reach and render a decision in writing (concurred
in by a majority of the members of the Board of Arbitration) with respect to the
amount, if any, which the losing party is required to pay to the other party in
respect of a claim filed. In connection with rendering its decisions, the Board
of Arbitration shall adopt and follow the laws of the State of California. To
the extent practical, decisions of the Board of Arbitration shall be rendered no
more than thirty (30) calendar days following commencement of proceedings with
respect thereto. The Board of Arbitration shall cause its written decision to be
delivered to all parties involved in the dispute. The Board of Arbitration shall
be authorized and is directed to enter a default judgment against any party
refusing to participate in the arbitration proceeding within thirty days of any
deadline for such participation. Any decision made by the Board of Arbitration
(either prior to or after the expiration of such thirty (30) calendar day
period) shall be final, binding and conclusive on the parties to the dispute,
and entitled to be enforced to the fullest extent permitted by law and entered
in any court of competent jurisdiction. The prevailing party shall be awarded
its costs, including attorneys' fees, from the non-prevailing party as part of
the arbitration award. Any party shall have the right to seek injunctive relief
from any court of competent jurisdiction in any case where such relief is
available. The prevailing party in such injunctive action shall be awarded its
costs, including attorney's fees, from the non-prevailing party.

          Section 9.10. Counterparts.  This Agreement may be executed in any
                        ------------
number of counterparts, all of which taken together shall constitute one and the
same instrument and shall become effective when counterparts have been signed by
each party and delivered to the other parties hereto, it being understood that
all parties need not sign the same counterpart. Execution may be made by
delivery by facsimile.

          Section 9.11. Publicity.  Prior to the Initial Closing, neither the
                        ---------
Company nor the Purchaser shall issue any press release or otherwise make any
public statement or announcement with respect to this Agreement or the
transactions contemplated hereby or the existence of this Agreement. After the
Initial Closing, the Company may issue a press release or otherwise make

                                       25
<PAGE>

a public statement or announcement with respect to this Agreement or the
transactions contemplated hereby or the existence of this Agreement; provided,
however, that prior to issuing any such press release, making any such public
statement or announcement, the Company obtains the prior consent of the
Purchaser, which consent shall not be unreasonably withheld or delayed; and,
further provided, that the Purchaser's consent shall not be necessary with
respect to any press release or public statement that contains no information
that differs materially from the substance of a press release or public
statement theretofore approved by the Purchaser. The Purchaser shall not
publicly disclose to any third party the receipt of any Draw Down Notice, or the
timing or existence of any Draw Down, Draw Down Pricing Period, Settlement Date
or Settlement Period; provided however, that the foregoing shall not prevent the
Purchaser from making any such disclosure to its business and/or professional
advisers, persons to whom disclosure is deemed necessary in order effectuate the
sale of the Shares pursuant to the Registration Statement or as may be required
by applicable laws, rules and regulations.

          Section 9.12. Severability.  The provisions of this Agreement are
                        ------------
severable and, in the event that any court or officials of any regulatory agency
of competent jurisdiction shall determine that any one or more of the provisions
or part of the provisions contained in this Agreement shall, for any reason, be
held to be invalid, illegal or unenforceable in any respect, such invalidity,
illegality or unenforceability shall not affect any other provision or part of a
provision of this Agreement and this Agreement shall be reformed and construed
as if such invalid or illegal or unenforceable provision, or part of such
provision, had never been contained herein, so that such provisions would be
valid, legal and enforceable to the maximum extent possible, so long as such
construction does not materially adversely effect the economic rights of either
party hereto.

          Section 9.13. Further Assurances.  From and after the date of this
                        ------------------
Agreement, upon the request of the Purchaser or the Company, each of the Company
and the Purchaser shall execute and deliver such instruments, documents and
other writings as may be reasonably necessary or desirable to confirm and carry
out and to effectuate fully the intent and purposes of this Agreement.

                                       26
<PAGE>

          IN WITNESS WHEREOF, the parties hereto have caused this Agreement to
be duly executed by their respective authorize officer as of the date first
above written.

                                    HOLLIS-EDEN PHARMACEUTICALS, INC.

                                    By:____________________________________

                                    BALLSBRIDGE FINANCE LTD.

                                    By:____________________________________
                                        Name:
                                        Title:

                                       27
<PAGE>

                                                                       EXHIBIT B

                               ESCROW AGREEMENT

     ESCROW AGREEMENT ("Escrow Agreement") dated as of September __, 2001, by
and between HOLLIS-EDEN PHARMACEUTICALS, INC., a Delaware corporation (the
"Company"), BALLSBRIDGE FINANCE LTD., a Nevis corporation (the "Purchaser"), and
ATLAS PEARLMAN, P.A., a Florida professional association (the "Escrow Agent").

                              W I T N E S S E T H
                              - - - - - - - - - -

     WHEREAS, the Company and the Purchaser are parties to a Common Stock
Purchase Agreement of even date herewith (the "Acquisition Agreement").  Unless
otherwise defined herein, capitalized terms shall have the meanings accorded to
them in the Acquisition Agreement; and

     WHEREAS, the Acquisition Agreement contemplates that, from time-to-time
during the Commitment Period,  the Company will sell to the Purchaser and the
Purchaser will purchase from the Company, up to $10,000,000 in shares of the
Company's Common Stock; and

     WHEREAS, in furtherance of the Acquisition Agreement, prior to each
Settlement Date, (i) the Company and the Purchaser shall each execute and
deliver to the other, and the Escrow Agent, via facsimile transmission, a
Settlement Certificate in the Form of Exhibit A, quantifying the amount of the
Draw Down and the number of shares of Common Stock to be purchased (the
"Settlement Certificate"),  (ii) the Company will file a supplement to the
prospectus forming a part of the Registration Statement and deliver a copy of
the prospectus and prospectus supplement (the "Prospectus, as Supplemented") to
the Purchaser and the Escrow Agent prior to the release of funds by the Escrow
Agent,  (iii) the Company shall cause the delivery of that number of whole
shares of Common Stock of the Company specified in the Settlement Certificate
(the "Subscription Shares"), via DWAC, to the account designated by the Escrow
Agent on Exhibit B (the "Escrow Shares Account"), and (iv) the Purchaser shall
transmit payment in an amount equal to the payment specified in the Settlement
Certificate (the "Subscription Payment"), to the Escrow Agent, via wire transfer
to the account designated by the Escrow Agent on Exhibit C (the "Escrow Funds
Account"); and

     WHEREAS, in furtherance of the Acquisition Agreement, on each Settlement
Date (i) the Escrow Agent shall transmit the Subscription Payment (net of the
Escrow Agent fees and certain other expenses described in Section 7 hereof) to
the Company, via wire transfer, to the account designated by the Company on
Exhibit D (the "Company Account") and (ii) the Escrow Agent shall cause delivery
of the Subscription Shares to the Purchaser, via DWAC, to the account designated
by the Purchaser on Exhibit E (the "Purchaser Account"); and

     WHEREAS, the process of delivery of the Subscription Shares to the
Purchaser against delivery of the Subscription Payment to the Company is herein
referred to as "Settlement"; and

     WHEREAS, the Escrow Agent has agreed to facilitate Settlement, as
aforesaid, upon the terms and conditions set forth in this Agreement.
<PAGE>

     NOW, THEREFORE, for good and valuable consideration, the receipt and
adequacy of which are hereby acknowledged by each of the parties hereto, the
parties hereto hereby agree as follows:

     1.   Appointment of Escrow Agent.  The Company and the Purchaser hereby
          ---------------------------
appoint the Escrow Agent as escrow agent upon the terms and conditions set forth
herein, and the Escrow Agent hereby accepts such appointment.

     2.   Delivery of Escrow Property.
          ---------------------------

          (a)  At least one day prior to each Settlement Date, (i) the Company
and the Purchaser shall each execute and deliver to the other, and the Escrow
Agent, via facsimile transmission, a Settlement Certificate relating to the
applicable Settlement,  (ii) the Company will file a supplement to the
prospectus forming a part of the Registration Statement and deliver a copy of
the Prospectus, as Supplemented, to the Purchaser and the Escrow Agent,  (iii)
the Company shall cause delivery of the Subscription Shares to be made into the
Escrow Shares Account, via DWAC, and (iv) the Purchaser shall cause transmission
of the Subscription Payment to be made, via wire transfer, into the Escrow Funds
Account.

          (b)  The Escrow Fund Account and the Escrow Shares Account are
hereinafter collectively referred to as the "Escrow Accounts" and the
Subscription Payments and the Subscription Shares are hereinafter collectively
referred to as the "Escrow Property."

     3.   Investment of the Escrow Property.  The Escrow Accounts shall not
          ---------------------------------
bear interest and no investment of the Escrow Property shall be made while held
by the Escrow Agent.

     4.   Release of Escrow Property. Provided that the Escrow Agent shall
          --------------------------
have received a signed copy of the Settlement Certificate, a copy of the
Prospectus, as Supplemented, along with evidence of its filing with the SEC, the
Subscription Shares and the Subscription Payment, all as aforesaid, on each
Settlement Date:

          (a)  the Escrow Agent shall transmit the applicable Subscription
Payment (net of the Escrow Agent fees and other expenses described in Section 7
hereof), via wire transfer, to the Company Account; and

          (b)  the Escrow Agent shall cause the delivery of the applicable
Subscription Shares, via DWAC, to the Purchaser Account.

     5.   Disbursement Into Court.  At any time, the Escrow Agent, in its sole
          -----------------------
discretion, may commence an action in the nature of interpleader in any court it
deems appropriate, to determine ownership or disposition of the Escrow Property
or it may deposit the Escrow Property with the clerk of any appropriate court or
it may retain the Escrow Property pending receipt of a final, non-appealable
order of a court having jurisdiction over all of the parties hereto directing to
whom and under what circumstances the Escrow Property are to be disbursed and
delivered. During the pendency of any such action, the Escrow Agent may suspend
the

                                       2
<PAGE>

performance of any of its obligations under this Escrow Agreement until such
dispute or uncertainty shall be resolved to the sole satisfaction of Escrow
Agent or until a successor Escrow Agent shall have been appointed (as the case
may be). The Escrow Agent shall have no liability to the Company, the Purchaser
or any other person with respect to any such suspension of performance or
disbursement into court, specifically including any liability or claimed
liability that may arise, or be alleged to have arisen, out of or as a result of
any delay in the disbursement of funds held in the Escrow Accounts or any delay
in or with respect to any other action required or requested of Escrow Agent.

     6.   Limitation of Responsibility and Liability and Duties of the Escrow
          -------------------------------------------------------------------
Agent. The acceptance by the Escrow Agent of its duties as such under this
-----
Escrow Agreement is subject to the following terms and conditions, which all
parties to this Escrow Agreement hereby agree shall govern and control with
respect to the rights, duties, liabilities and immunities of the Escrow Agent:

          (a)  The Escrow Agent shall not be liable for any error in judgment or
mistake of law or fact, or for any action taken or omitted to be taken by it, or
any action suffered by it to be taken or omitted by it, in good faith and in the
exercise of its own best judgment, and may rely conclusively and shall be
protected in acting upon any order, notice, demand, certificate, opinion or
advice of counsel (including counsel chosen by the Escrow Agent), statement,
instrument, report or other paper or document (not only as to its due execution
and validity and effectiveness of its provisions, but also as to the truth and
acceptability of any information therein contained) which is believed by the
Escrow Agent to be genuine and to be signed or presented by the proper person or
persons.  The Escrow Agent shall not be bound by any notice or demand, or any
waiver, modification, termination or rescission of this Escrow Agreement unless
evidenced by a writing delivered to the Escrow Agent signed by the Company and
the Purchaser and, if the duties or rights of the Escrow Agent are affected by
any such modification of or waiver under this Escrow Agreement unless the Escrow
Agent shall have given its prior written consent thereto.

          (b)  The Escrow Agent acts hereunder as a depositary only, and shall
not be responsible for the sufficiency or accuracy, the form of, or the
execution, validity, value or genuineness of any document or property received,
held or delivered by it hereunder, or of any signature or endorsement thereon,
or for any lack of endorsement thereon, or for any description therein, nor
shall the Escrow Agent be responsible or liable in any respect on account of the
identity, authority or rights of the persons executing or delivering or
purporting to execute or deliver any document or property paid or delivered by
the Escrow Agent pursuant to the provisions hereof.

          (c)  The Escrow Agent shall have the right to assume, in the absence
of written notice to the contrary from the Company and the Purchaser, that a
fact or an event by reason of which an action would or might be taken by the
Escrow Agent does not exist or has not occurred, without incurring liability for
any action taken or omitted, in good faith and in the exercise of its own best
judgment, in reliance upon such assumption.

                                       3
<PAGE>

          (d)  The Escrow Agent shall be indemnified and held harmless by the
Company and the Purchaser, upon demand by the Escrow Agent, from and against any
claims, demands, losses, damages, liabilities, costs and expenses, including
counsel fees and disbursements, (collectively, "Damages") suffered by the Escrow
Agent in connection with any action, suit or other proceeding involving any
claim, or in connection with any claim or demand, which in any way directly or
indirectly arises out of or relates to this Escrow Agreement, the services of
the Escrow Agent hereunder, the monies or other property held by it hereunder or
any such Damages.  Promptly after the receipt by the Escrow Agent of notice of
any demand or claim or the commencement of any action, suit or proceeding, the
Escrow Agent shall, if a claim in respect thereof shall be made against the
other parties hereto, notify such parties thereof in writing; but the failure by
the Escrow Agent to give such notice shall not relieve any party from any
liability which such party may have to the Escrow Agent hereunder, except to the
extent of actual prejudice demonstrated by such party.  The obligations of the
Company and the Purchaser under this Section 6(d) shall survive any termination
of this Escrow Agreement and the resignation or removal of the Escrow Agent..

          (e)  From time to time on and after the date hereof, the parties shall
deliver or cause to be delivered to the Escrow Agent such further documents and
instruments and shall do or cause to be done such further acts as the Escrow
Agent shall reasonably request (it being understood that the Escrow Agent shall
have no obligation to make such request) to carry out more effectively the
provisions and purposes of this Escrow Agreement, to evidence compliance
herewith or to assure itself that it is protected in acting hereunder.

          (f)  The Escrow Agent may resign at any time and be discharged from
its duties as Escrow Agent hereunder by its giving the other parties hereto
prior written notice of at least seven (7) business days. As soon as practicable
after its resignation, the Escrow Agent shall turn over to a successor escrow
agent appointed by the other parties hereto, jointly, all of the Escrow Property
held hereunder upon presentation of the document appointing the new escrow agent
and its acceptance thereof. If no new escrow agent is so appointed within the
twenty (20) day period following the giving of such notice of resignation, the
Escrow Agent may deposit the Escrow Property with any court it deems
appropriate.

          (g)  The Escrow Agent may consult with, and obtain advice from, legal
counsel in the event of any dispute or question as to the construction of any of
the provisions hereof or its duties hereunder, and it shall incur no liability
and shall be fully protected in acting in good faith in accordance with the
opinion and instructions of such counsel.

          (h)  The Escrow Agent is authorized, in its sole discretion, to comply
with orders issued or process entered by any court with respect to the Escrow
Property, without determination by the Escrow Agent of such court's jurisdiction
in the matter.  If any portion of the Escrow Property is at any time attached,
garnished or levied upon under any court order, or in case the payment,
assignment, transfer, conveyance or delivery of any such property shall be
stayed or enjoined by any court affecting such property or any part thereof,
then and in any such event, the Escrow Agent is authorized, in its sole
discretion, to rely upon and comply with any such order, writ, judgment or
decree which it is advised by legal counsel selected by it is binding upon it
without the need for appeal or other action; and if the Escrow Agent complies
with any

                                       4
<PAGE>

such order, writ, judgment or decree, it shall not be liable to any of the
parties hereto or to any other person or entity by reason of such compliance
even though such order, writ, judgment or decree may be subsequently reversed,
modified, annulled, set aside or vacated.

          (i)  The parties acknowledge that the Escrow Agent has acted as
counsel to the Purchaser and/or its affiliates in various matters, including in
connection with the transactions contemplated by the Acquisition Agreement, and
has prepared this Escrow Agreement, and may continue to act as counsel to the
Purchaser and/or its affiliates during and following the term of this Escrow
Agreement. All parties to this Escrow Agreement waive any conflicts that exist
or may arise by reason of such representation; provided, however, that the
Escrow Agent shall ensure that the Escrow Accounts are under the sole control of
the Escrow Agent.

     7.   [intentionally left blank]
          --------------------------

     8.   Fees of Escrow Agent.  The Escrow Agent shall be compensated for its
          --------------------
services hereunder at the rate of one thousand dollars ($1,000) for each
Settlement facilitated by the Escrow Agent.  The compensation obligations set
forth in this Section 8 shall be payable by the Company from Settlements
Payments, prior to disbursement to the Company.  The obligations under this
Section 8 shall survive any termination of this Escrow Agreement and the
resignation or removal of Escrow Agent.

     9.   Governing Law; Jurisdiction, Venue.  This Escrow Agreement shall be
          ----------------------------------
governed by and construed and enforced in accordance with the law (other than
the law governing conflict of law questions) of the State of Florida. Except as
otherwise set forth herein, any suit, action or proceeding arising out of or
relating to this Escrow Agreement shall be brought in State Circuit Court or
Federal District Court located in Broward County, Florida, and the parties
hereby (a) submit to the exclusive jurisdiction of such courts, (b) waive any
objection to the laying of venue in such courts, and (c) agree that service of
process in any such suit, action or proceeding may, in addition to any other
method permitted by applicable law, may be effected by certified mail, return
receipt requested, to a party at its address set forth in Section 10 hereof.

     10.  Notices.  All notices and communications shall be deemed to have
          -------
been duly given:  at the time (a) delivered by hand, if personally delivered;
(b) when received, if deposited in the mail, postage prepaid, addressed as
provided below; (c) when transmission is verified, if telecopied; and (d) on the
next business day, if timely delivered to a courier service guaranteeing
overnight delivery; provided that the Escrow Agent shall have no obligation
hereunder unless notice is actually received by it;

          To the Company:     HOLLIS-EDEN PHARMACEUTICALS INC.
                              9333 Genesee Avenue
                              Suite 200
                              San Diego, California 92121
                              Facsimile No.: (858) 587-0896
                              Attention: Daniel Burgess, Chief Financial Officer
                              and Eric Loumeau, V.P. and General Counsel

                                       5
<PAGE>

          To the Purchaser:        BALLSBRIDGE FINANCE LTD.
                                   38 Hertford Street
                                   London W1Y 7TG United Kingdom
                                   Facsimile No.: 011-44-207-355-4975
                                   Attention: Mr. James Martin

          To the Escrow Agent:     ATLAS PEARLMAN, P.A.,
                                   as Escrow Agent
                                   350 East Las Olas Blvd.
                                   17/th/ Floor
                                   Fort Lauderdale, Florida 33301
                                   Facsimile No.: 954-766-7800
                                   Attention: Steven I. Weinberger, Esq.

Any party may change its address by providing written notice of such change to
the other parties hereto.  All notices and communications provided by the
Company and/or the Purchaser to the Escrow Agent shall be signed by duly
authorized persons of each.

     11.  Termination of Escrow Agreement.  The Escrow Agent's responsibilities
          -------------------------------
hereunder shall terminate upon the earliest to occur of the termination of the
Acquisition Agreement, the termination or rescission of this Agreement by mutual
consent of the Company and the Purchaser, the disbursement of the Escrow
Property into court under Section 5 hereof, and the resignation of the Escrow
Agent under Section 6(f) hereof.

     12.  Entire Escrow Agreement.  This Escrow Agreement (and the exhibits
          -----------------------
attached hereto) contains the entire understanding by and among the parties
hereto with respect to the subject matter hereof; there are no promises,
agreements, understandings, representations or warranties, other than as herein
set forth.  No change or modification of this Escrow Agreement shall be valid or
effective unless the same is in writing and is signed by all of the parties
hereto.

     13.  Counterparts.  This Escrow Agreement may be executed in two or more
          ------------
counterparts, each of which shall be deemed an original, but all of which shall
constitute one and the same agreement.

                                       6
<PAGE>

     IN WITNESS WHEREOF, the parties hereto have caused their respective hands
to be set hereto with the intention of being bound effective in all respects as
of the date and year first hereinabove written.

                              HOLLIS-EDEN PHARMACEUTICALS, INC.

                              By:______________________________
                              Its:_____________________________

                              BALLSBRIDGE FINANCE LTD.

                              By:______________________________
                              Its:_____________________________

                              ATLAS PEARLMAN, P.A.

                              By:______________________________
                              Its:_____________________________

                                       7
<PAGE>

                                   EXHIBIT A

                        FORM OF SETTLEMENT CERTIFICATE

<PAGE>

                       HOLLIS-EDEN PHARMACEUTICALS, INC.

                            SETTLEMENT CERTIFICATE

     This Settlement Certificate is executed and delivered in furtherance of (i)
the Common Stock Purchase Agreement dated September ___, 2001 (the "Acquisition
Agreement"), by and between Hollis-Eden Pharmaceuticals, Inc. (the "Company")
and Ballsbridge Finance Ltd. (the "Purchaser") and (ii) the Escrow Agreement
dated September ___, 2001 (the "Escrow Agreement"), by and among the Company,
the Purchaser and Atlas Pearlman, P.A. (the "Escrow Agent").  Unless otherwise
defined herein, capitalized terms shall have the meanings ascribed to them in
the Acquisition Agreement and the Escrow Agreement.

     Settlement Date:              __________________________

     Investment Amount:            $_________________________

     Number of Shares to be
     Delivered to the Purchaser:   __________________________

     Escrow Agent Fee:             $_________________________

     Net Proceeds to be
     Delivered to the Company:     $_________________________

     Settlement of this transaction shall take place in the manner described in
the Acquisition Agreement and the Escrow Agreement.

     Purchase of the Shares shall be on a delivery versus payment basis, as more
fully described in the Acquisition Agreement and the Escrow Agreement.

     By its execution of this Settlement Certificate, the Company hereby
certifies that each of its representations and warranties in the Acquisition
Agreement is true and accurate on the date hereof and that the Company has
satisfied each condition precedent to the transaction evidenced by this
Settlement Certificate and remains in compliance with each and every obligation
and covenant made by it in the Acquisition Agreement. Without limitation of the
foregoing, the Company hereby certifies that (i) the Registration Statement has
become effective under the Securities Act of 1933, as amended (the Securities
Act"), (ii) the Registration Statement and prospectus included therein is
current and no stop order is in effect with respect to its use and (iii) the
Company has filed, or prior to the Settlement Date will file, a prospectus
supplement with respect to the Purchaser's resale of the Shares.
<PAGE>

     By its execution of this Settlement Certificate, the Purchaser hereby
certifies that (i) each of its representations and warranties in the Acquisition
Agreement is true and accurate on the date hereof (ii) the Purchaser has
satisfied each condition precedent to the transaction contemplated by this
Settlement Certificate and remains in compliance with each and every obligation
and covenant made by it in the Acquisition Agreement and (iii) it will timely
comply with applicable prospectus delivery requirements under the Securities Act
in connection with its resale of the Shares.

     The Escrow Agent is hereby directed to comply with the provisions of
Section 4 of the Escrow Agreement without further instruction by or notice to
the Company or the Purchaser.

HOLLIS-EDEN                                  BALLSBRIDGE FINANCE LTD.
PHARMACEUTICALS, INC.

By:____________________________              By:________________________
Date:                                       Date:
<PAGE>

                                                                       EXHIBIT C

              FORM OF OPINION OF THE COMPANY'S INDEPENDENT COUNSEL

September ___, 2001

Ballsbridge Finance Ltd.
38 Hertford Street
London, United Kingdom W1Y 7TG

RE:  Hollis-Eden Pharmaceuticals, Inc.

Ladies and Gentlemen:

     We have acted as counsel to Hollis-Eden Pharmaceuticals, Inc., a Delaware
corporation (the "Company"), with the negotiation of: (i) the Common Stock
Purchase Agreement by and between Ballsbridge Finance Ltd. (the "Purchaser") and
the Company, dated as of September __, 2001 (the "Purchase Agreement"), which
provides for the issuance and sale by the Company of up to $10,000,000 of Common
Stock, the specific number of which shall be determined in accordance with the
terms of the Purchase Agreement bust shall not exceed _____ shares (the
"Shares") of the Company, and Warrants to purchase up to 50,000 shares of the
Company's Common Stock (the "Warrants"); (ii) the Warrants issued by the Company
at the Closing; (iii) the Registration Rights Agreement between the Purchaser
and the Company, dated as of September __, 2001 (the "Registration Rights
Agreement"); and (iv) the Escrow Agreement between the Purchaser, the Company
and Atlas Pearlman, P.A., as Escrow Agent, dated as of September __, 2001 (the
"Escrow Agreement", and collectively with the Purchase Agreement, the Warrants
and the Registration Rights Agreement, the "Agreements"). We are rendering this
opinion pursuant to Section 5.2(e) of the Purchase Agreement. The Registration
Statement on Form S-1, as amended, originally filed on September __, 2001 (No.
_________), when it became effective, is hereinafter called "Registration
Statement," [and the Prospectus in the form first filed with the Securities and
Exchange Commission pursuant to Rule 424(b) and Rule 430A is hereinafter called
the "Prospectus."] Except as otherwise defined herein, capitalized terms used
herein have the respective meanings given to them in the Purchase Agreement.

     In connection with this opinion, we have examined and relied upon
representations and warranties as to factual matters contained in, and made
pursuant to, the Purchase Agreement by the various parties thereto, and have
examined and relied upon the originals or copies of such records, documents,
certificates, opinions, memoranda and other instruments as in our judgment are
necessary to enable us to render the opinion expressed below.

     As to certain factual matters, we have relied upon certificates of officers
of the Company and have not sought independently to verify such matters. Where
we render an opinion "to the best of our knowledge" or concerning an item "known
to us" or our opinion otherwise refers to our knowledge, it is based solely upon
(i) an inquiry of attorneys within the firm who perform legal services for the
Company solely in connection with the Agreements or the transactions
contemplated thereby, (ii) the receipt of a certificate executed by an officer
of the Company
<PAGE>

covering such matters, and (iii) such other investigation, if any, that we
specifically set forth herein.

     In rendering this opinion, we have assumed: the genuineness and
authenticity of all signatures on original documents; the authenticity of all
documents submitted to us as originals; the conformity to originals of all
documents submitted to us as copies; the accuracy, completeness and authenticity
of certificates of public officials; and the due authorization, execution and
delivery of all documents (except the due authorization, execution and delivery
by the Company of the Agreements), where authorization, execution and delivery
are prerequisites to the effectiveness of such documents. We have also assumed:
that all individuals executing and delivering documents in their individual
capacities had the legal capacity to so execute and deliver; that the Agreements
are obligations binding upon you and each of the Purchasers; that you and the
other Purchasers have each filed any required California franchise or income tax
returns and paid any required California franchise or income taxes; and that
there are no extrinsic agreements or understandings among the parties to the
Agreements or the material agreements or other instruments in the form filed by
the Company as exhibits to the Registration Statement, that would modify or
interpret the terms thereof or the respective rights or obligations of the
parties thereunder.

     With regard to our opinion in paragraph 2 below, with respect to the
Company's qualification to transact business, we have examined and relied upon a
certificate executed by an officer of the Company setting forth the states in
which the Company leases property and in which the Company has employees, and we
have undertaken no independent verification with respect thereto.

     With regard to our opinion in paragraphs 5 and 7 below, with respect to any
registration right, preemptive or other similar right we have relied solely on
(a) an inquiry of the attorneys in the firm who perform legal services for the
Company, (b) the receipt of a certificate executed by an officer of the Company
covering such matters, (c) inquiries of the President and Chief Financial
Officer of the Company, and (d) an examination of the Company's Certificate of
Incorporation as in effect on the date hereof (the "Certificate"), its Bylaws
and the material agreements or other instruments in the form filed or
incorporated by reference by the Company as exhibits to the Registration
Statement (the "Material Agreements"); we have made no further investigation.

     [With regard to paragraph 10 below, our opinion is based solely upon oral
advice from the staff of the Commission that the Registration Statement was
declared effective under the 1933 Act at ____ p.m. Eastern time on ____________,
2001, and that no stop order suspending the effectiveness of the Registration
Statement has been issued and that no proceedings for that purpose have been
initiated or are pending or contemplated by the Commission. We have made no
other investigation in connection therewith.]

     Our opinion is expressed only with respect to the federal laws of the
United States of America, the laws of the State of California and the General
Corporation Law of the State of Delaware. We express no opinion as to whether
the laws of any particular jurisdiction apply, and no opinion to the extent that
the laws of any jurisdiction other than those identified above are

                                       2
<PAGE>

applicable to the subject matter hereof. We are not rendering any opinion as to
compliance with any antifraud law, rule or regulation relating to securities, or
to the sale or issuance thereof.

     On the basis of the foregoing and in reliance thereon, and subject to the
qualifications herein stated, we are of the opinion that:

     1. The Company has been duly incorporated and is validly existing in good
standing under the laws of the State of Delaware. The Company has the requisite
corporate power to own or lease its property and assets, to conduct its business
as described in the Prospectus and to enter into and perform its obligations
under the Agreements.

     2. To the best of our knowledge, the Company is duly qualified to do
business as a foreign corporation and is in good standing in all other
jurisdictions in which its ownership or lease of property or the conduct of its
business requires such qualification, except where the failure to be so
qualified or be in good standing would not have a Material Adverse Effect.

     3. The execution and delivery of the Agreements by the Company and the
issuance of the Shares, the Warrants and the shares of the Company's Common
Stock issuable upon exercise of the Warrants (the "Warrant Shares") have been
duly authorized by all requisite corporate action on the part of the Company.
Each of the Agreements has been duly executed and delivered on behalf of the
Company and each of the Agreements constitutes a valid and binding obligation of
the Company enforceable against the Company in accordance with its respective
terms, except (i) as limited by applicable bankruptcy, insolvency,
reorganization, arrangement, moratorium and other laws of general applicability
related to or affecting creditors' rights, (ii) as limited by equitable
principles generally and limitations on the availability of equitable remedies,
whether such enforceability is considered in a proceeding in equity or at law,
and (iii) for those provisions of Article VIII of the Purchase Agreement and
Sections 6 and 7 of the Registration Rights Agreement relating to indemnity or
contribution.

     4. The issuance of the Shares, the Warrant and the Warrant Shares as
contemplated by the Agreements as of the Closing Date, will not violate or
contravene or be in conflict with: (i) the Company's Certificate or Bylaws; (ii)
the Material Agreements to which the Company is a party; or (iii) any provision
of the General Corporation Law of the State of Delaware and any provision of any
federal or California law, rule or regulation applicable to the Company in
securities and commercial transactions of the nature contemplated by the
Agreements.

     5. When issued, delivered and paid for in accordance with the terms of the
Agreements, the Shares and Warrant Shares will be validly issued, fully paid and
nonassessable, and the issuance of the Shares and the Warrant Shares is not
subject to any preemptive rights of stockholders of the Company contained in the
Company's Certificate, or similar rights contained in the Company's Bylaws or
the Material Agreements.

     6. Except as set forth in the Prospectus, to our knowledge, there is no
action, proceeding or investigation pending or overtly threatened in writing
against the Company which could reasonably be anticipated to result, either
individually or in the aggregate, in any material adverse change in the assets,
financial condition or operations of the Company.

                                       3
<PAGE>

     7. To our knowledge, there are no outstanding options, warrants, calls or
commitments of any character whatsoever relating to, or securities, rights or
obligations convertible into or exchangeable for, or giving any right to
subscribe for or acquire any shares of Common Stock or contracts, commitments,
understanding, or arrangements by which the Company is or may become bound to
issue additional shares of Common Stock, or securities or rights convertible or
exchangeable into shares of Common Stock, except as described in the
Registration Statement or the Agreements. To our knowledge, the Company is not a
party to or subject to the provisions of any order, writ, injunction, judgment
or decree of any court or government agency or instrumentality.

     8. The issuance of the Shares and the Warrant Shares will not violate the
applicable listing agreement between the Company and the Nasdaq Stock Market,
Inc.

     9. The authorized, issued and outstanding capital stock of the Company is
as set forth in the Prospectus listed in the line item descriptions under the
caption "Capitalization" (except for subsequent issuances, if any, pursuant to
the Purchase Agreement or pursuant to reservations, agreements or employee
benefit plans referred to in the Prospectus or pursuant to the exercise of
convertible securities or options referred to in the Prospectus).

[Item 10 to be included in Opinion pursuant to Section 5.3 at each Draw Down.]

10. The Registration Statement has been declared effective by the SEC and no
stop order is in effect with respect to the Registration Statement.

  Our opinions set forth above are limited to the matters expressly set forth in
this opinion letter, and no opinion may be implied or may be inferred beyond the
matters expressly stated. This opinion speaks only as to law and facts in effect
or existing as of the date hereof and we undertake no obligation or
responsibility to update or supplement this opinion to reflect any facts or
circumstances that may hereafter come to our attention or any changes in any law
which may hereafter occur.

  Based upon our assumption that (i) the representations and warranties of the
Company and the Purchaser contained in the Purchase agreement are true and
correct, (ii) the Registration Statement is effective, (iii) the Prospectus does
not contain an untrue statement of a material fact or omit to state a material
fact required to be stated therein or necessary to make the statements therein
not misleading, (iv) the Purchaser complies with the prospectus delivery
requirements imposed by the Securities Act of 1933, as amended (the "Act"), (v)
the Purchaser transfers the Shares and/or the Warrant Shares according to the
plan of distribution described in the Prospectus, (vi) the contemplated transfer
is in compliance with applicable blue sky laws, and (vii) since the time of
filing of the Registration Statement, there has been no change in the law
affecting the transfer of the Shares and/or the Warrant Shares, we have advised
the Company that the Purchaser may transfer the Shares and/or the Warrant shares
without legend restriction their transferability under the Act.

     This opinion letter is intended solely for the benefit of the addressees of
this letter, and is not to be made available to or relied upon by any other
person, firm or entity without our prior

                                       4
<PAGE>

written consent (provided, that copies of this opinion letter may be made
available to the counsel, transferees and regulators of the addresses of this
letter).

Very truly yours,

                                       5
<PAGE>

                                                                       EXHIBIT D

                       HOLLIS-EDEN PHARMACEUTICALS, INC.

                           FORM OF DRAW DOWN NOTICE

TO:          BALLSBRIDGE FINANCE LTD.
             38 Hertford Street
             London, United Kingdom
             W1Y 7TG
             Attention: Mr. James Martin
             Telephone: 01144 207 355 2051
             Facsimile: 01144 207 355 4975

COPIES TO:   ISOSCELES CAPITAL, LTD.            COOLEY GODWARD LLP
             1/ST/ Floor, 55 Conduit Street     4365 Executive Drive, Suite 1100
             London, United Kingdom             San Diego, California
             W1R 9FD                            92121
             Attention: _________________       Attention: Thomas A. Coll, Esq.
             Telephone: 01144 207 494 5900      Telephone: 858-550-6013
             Facsimile: 01144 207 494 5901      Facsimile: 858-453-3555

             ATLAS PEARLMAN, P.A.
             350 East Las Olas Blvd.
             Suite 1700
             Fort Lauderdale, Florida
             33301
             Attention: Steven I. Weinberger,
             Esq.
             Telephone: 954-763-1200
             Facsimile: 954-766-7800

FROM:        HOLLIS-EDEN PHARMA-                DATE:________________
                   CEUTICALS, INC.

This Draw Down Notice is provided in Connection with the Common Stock Purchase
Agreement dated september ___, 2001, by and between Hollis-Eden Pharmaceuticals,
Inc. and Ballsbridge Finance Ltd. (the "Purchase Agreement", and the Escrow
Agreement relating thereto.  Words and Expressions Defined in the Purchase
Agreement and Escrow Agreement shall bear the same meanings as in this Notice
and the Terms and Conditions Contained in the Purchase Agreement and the Escrow
Agreement are hereby incorporated by reference and deemed to be a part of this
Notice.

                                       1
<PAGE>

1.   We wish to make a Draw Down against the Commitment Amount pursuant to the
     Purchase Agreement as follows:

--------------------------------------------------------------------------------
(a)  Investment Amount of this Draw Down
     Notice:
--------------------------------------------------------------------------------
(b)  Commencement Date (being the first
     Trading Day of the Draw Down Pricing
     Period):
--------------------------------------------------------------------------------
(c)  Number of Trading Days in the Draw Down
     Pricing Period (being 5, 10, 15 or 20
     Trading Days):
--------------------------------------------------------------------------------
(d)  Threshold Price (subject to a minimum
     of $______):
--------------------------------------------------------------------------------

2.   On the Settlement Date, we will deliver to the Escrow Agent such
     certificates and other documents, including a Abring-down@ opinion of
     counsel, to the extent required by the Purchase Agreement.

3.   We acknowledge that our delivery of this Notice is irrevocable.

4.   By our execution of this Notice, we hereby confirm that each of our
     representations and warranties in the Purchase Agreement is true and
     accurate on the date hereof, that we have satisfied each condition
     precedent to the Draw Down contemplated by this Notice and that we remain
     in compliance with each and every obligation and covenant made by us in the
     Purchase Agreement.  Without limitation of the foregoing, we hereby confirm
     that (i) the Registration Statement has become effective under the
     Securities Act of 1933, as amended, (ii) the Registration Statement and
     prospectus included therein is current and no stop order is in effect with
     respect to its use and (iii) we have filed, or prior to the Settlement Date
     will file, a prospectus supplement with respect to the Purchaser=s resale
     of the Shares covered by this Draw Down Notice.

5.   We agree that we are responsible for all reasonable fees and expenses
     incurred by us and by the Purchaser pursuant to this Draw Down Notice, to
     the extent provided in the Purchase Agreement.

6.  We confirm that the signed original of this Notice will be mailed to the
     above address by first class mail as soon as possible.

7.   Not later than the day prior to the Settlement Date, we will deliver
     certificates evidencing the Shares to the Escrow Agent, via DWAC, to the
     Escrow Shares Account designated for that purpose in the Escrow Agent.  On
     the Settlement Date, Subscription Proceeds evidencing the

                                       2
<PAGE>

     net purchase price for the Shares should be transmitted to us, via wire
     transfer, to the Company Account designated for that purpose in the Escrow
     Agreement.

8.   We confirm that the amount of this Draw Down, the purchase price per Share,
     the Settlement Date and adjustments, if any, to the number of Shares to be
     purchased, shall be computed and processed in the manner described in the
     Purchase Agreement.

                              HOLLIS-EDEN PHARMACEUTICALS, INC.

                              By: _______________________________
                                  Name:
                                  Title:

                         *  *  *  *  *  *  *  *  *  *

We hereby acknowledge receipt of the above Draw Down Notice and acknowledge our
obligation to purchase and pay for the Shares on the basis set out above and in
accordance with the terms of the Purchase Agreement.

                              BALLSBRIDGE FINANCE LTD.

                              By: _______________________________
                                  Name:
                                  Title:

                              Date: _____________________________

                                       3
<PAGE>

                                                                       EXHIBIT F

                       HOLLIS-EDEN PHARMACEUTICALS, INC.

                            SETTLEMENT CERTIFICATE

     This Settlement Certificate is executed and delivered in furtherance of (i)
the Common Stock Purchase Agreement dated September ___, 2001 (the "Acquisition
Agreement"), by and between Hollis-Eden Pharmaceuticals, Inc. (the "Company")
and Ballsbridge Finance Ltd. (the "Purchaser") and (ii) the Escrow Agreement
dated September ___, 2001 (the "Escrow Agreement"), by and among the Company,
the Purchaser and Atlas Pearlman, P.A. (the "Escrow Agent").  Unless otherwise
defined herein, capitalized terms shall have the meanings ascribed to them in
the Acquisition Agreement and the Escrow Agreement.

     Settlement Date:               _____________________________

     Investment Amount:             $____________________________

     Number of Shares to be
     Delivered to the Purchaser:    _____________________________

     Escrow Agent Fee:              $____________________________

     Net Proceeds to be
     Delivered to the Company:      $____________________________

     Settlement of this transaction shall take place in the manner described in
the Acquisition Agreement and the Escrow Agreement.

     Purchase of the Shares shall be on a delivery versus payment basis, as more
fully described in the Acquisition Agreement and the Escrow Agreement.

     By its execution of this Settlement Certificate, the Company hereby
certifies that each of its representations and warranties in the Acquisition
Agreement is true and accurate on the date hereof and that the Company has
satisfied each condition precedent to the transaction evidenced by this
Settlement Certificate and remains in compliance with each and every obligation
and covenant made by it in the Acquisition Agreement.  Without limitation of the
foregoing, the Company hereby certifies that (i) the Registration Statement has
become effective under the Securities Act of 1933, as amended (the Securities
Act"), (ii) the Registration Statement and prospectus included therein is
current and no stop order is in effect with respect to its use and
<PAGE>

(iii) the Company has filed, or prior to the Settlement Date will file, a
prospectus supplement with respect to the Purchaser's resale of the Shares.

     By its execution of this Settlement Certificate, the Purchaser hereby
certifies that (i) each of its representations and warranties in the Acquisition
Agreement is true and accurate on the date hereof  (ii) the Purchaser has
satisfied each condition precedent to the transaction contemplated by this
Settlement Certificate and remains in compliance with each and every obligation
and covenant made by it in the Acquisition Agreement and (iii) it will timely
comply with applicable prospectus delivery requirements under the Securities Act
in connection with its resale of the Shares.

     The Escrow Agent is hereby directed to comply with the provisions of
Section 4 of the Escrow Agreement without further instruction by or notice to
the Company or the Purchaser.

HOLLIS-EDEN                             BALLSBRIDGE FINANCE LTD.
PHARMACEUTICALS, INC.

By:___________________________          By:_________________________
Date:                                   Date:<PAGE>

                                                                   EXHIBIT 10.15

                         REGISTRATION RIGHTS AGREEMENT

          THIS REGISTRATION RIGHTS AGREEMENT, dated as of September __, 2001
between Ballsbridge Finance Ltd. ("Purchaser") and Hollis-Eden Pharmaceuticals,
Inc. (the "Company").

          WHEREAS, simultaneously with the execution and delivery of this
Agreement, pursuant to a Common Stock Purchase Agreement dated the date hereof
(the "Purchase Agreement") the Purchaser has committed to purchase up to
$10,000,000 of the Company's Common Stock (terms not defined herein shall have
the meanings ascribed to them in the Purchase Agreement) and Warrants; and

          WHEREAS, the Company desires to grant to the Purchaser the
registration rights set forth herein with respect to the Shares and the shares
issuable upon exercise of the Warrants from time to time (collectively, the
"Securities").

          NOW, THEREFORE, the parties hereto mutually agree as follows:

          Section 1.  Registrable Securities.  As used herein the term
                      ----------------------
"Registrable Security" means the Securities until (i) all Securities have been
disposed of pursuant to the Registration Statement, (ii) all Securities have
been sold under circumstances under which all of the applicable conditions of
Rule 144 (or any similar provision then in force) under the Securities Act
("Rule 144") are met, (iii) all Securities have been otherwise transferred to
persons who may trade such Securities without restriction under the Securities
Act, and the Company has delivered a new certificate or other evidence of
ownership for such Securities not bearing a restrictive legend or (iv) such time
as, in the opinion of counsel to the Company, all Securities may be sold without
any time, volume or manner limitations pursuant to Rule 144(k) (or any similar
provision then in effect) under the Securities Act.  The term "Registrable
Securities" means any and/or all of the securities falling within the foregoing
definition of a "Registrable Security."  In the event of any merger,
reorganization, consolidation, recapitalization or other change in corporate
structure affecting the Common Stock, such adjustment shall be deemed to be made
in the definition of "Registrable Security" as is appropriate in order to
prevent any dilution or enlargement of the rights granted pursuant to this
Agreement.

          Section 2.  Restrictions on Transfer.  The Purchaser acknowledges and
                      ------------------------
understands that in the absence of an effective Registration Statement
authorizing the resale of the Securities as provided herein, the Securities are
"restricted securities" as defined in Rule 144.  The Purchaser understands that
no disposition or transfer of the Securities may be made by Purchaser in the
absence of (i) an opinion of counsel to the Purchaser, in form and substance
reasonably satisfactory to the Company, that such transfer may be made without
registration under the Securities Act or (ii) such registration.

          With a view to making available to the Purchaser the benefits of Rule
144, the Company agrees to:
<PAGE>

               (a) comply with the provisions of paragraph (c)(1) of Rule 144;
and

               (b) file with the Commission in a timely manner all reports and
other documents required to be filed by the Company pursuant to Section 13 or
15(d) under the Exchange Act; and, if at any time it is not required to file
such reports but in the past had been required to or did file such reports, it
will, upon the request of the Purchaser, make available other information as
required by, and so long as necessary to permit sales of, its Registrable
Securities pursuant to Rule 144.

          Section 3.  Registration Rights With Respect to the Securities.
                      --------------------------------------------------

               (a) The Company agrees that it will prepare and file with the
Securities and Exchange Commission ("Commission"), within forty-five (45) days
after the date hereof, a registration statement on Form S-3, if the Company
qualifies to use Form S-3 in connection with the transactions contemplated by
the Purchase Agreement (or, if the Company does not so qualify, on Form S-1 or
other appropriate form of registration statement) under the Securities Act (the
"Registration Statement"), at the sole expense of the Company (except as
provided in Section 3(c) hereof), in respect of Purchaser, so as to permit a
public offering and resale of the Securities under the Securities Act by
Purchaser.

          The Company shall use its commercially reasonable efforts to cause the
Registration Statement to become effective as expeditiously as practicable but
in no event later than ninety (90) days from the date hereof or five (5) days of
SEC clearance and will within said five (5) days request acceleration of
effectiveness.  The Company will notify Purchaser of the effectiveness of the
Registration Statement within one Trading Day of such event.

               (b) The Company will maintain the Registration Statement or post-
effective amendment filed under this Section 3 hereof effective under the
Securities Act until the earliest of (i) the date that all the Securities have
been disposed of pursuant to the Registration Statement, (ii) the date that the
all of the Securities may be sold under the provisions of Rule 144 without
limitation as to volume, (iii) the date all Securities may be sold without
restriction under the Securities Act, and the Company has delivered a new
certificate or other evidence of ownership for such securities not bearing a
restrictive legend, or (iv) the date all Securities may be sold without any
time, volume or manner limitations pursuant to Rule 144(k) or any similar
provision then in effect under the Securities Act (the "Effectiveness Period").

               (c) All fees, disbursements and out-of-pocket expenses and costs
incurred by the Company in connection with the preparation and filing of the
Registration Statement under subparagraph 3(a) and in complying with applicable
securities and Blue Sky laws (including, without limitation, all attorneys' fees
of the Company) shall be borne by the Company.  The Company shall also bear the
costs and expenses of preparing and filing one prospectus supplement in
connection with a transfer by the Purchaser of all or a portion of the Warrants.
Prospectus supplements necessitated by subsequent transfers of Warrants, if any,
shall be at the expense of the Purchaser.  The Purchaser shall bear the cost of
underwriting and/or brokerage discounts, fees and commissions, if any,
applicable to the Securities being registered and the fees and expenses of its
counsel.  The Purchaser and its counsel shall have a reasonable

                                       2
<PAGE>

period, not less than three (3) Trading Days, to review the proposed
Registration Statement or any amendment thereto, prior to filing with the
Commission, and the Company shall provide the Purchaser with copies of any
comment letters received from the Commission with respect thereto within two (2)
Trading Days of receipt thereof. Prior to the filing of the Registration
Statement pursuant to Section 3(a), the Company shall make reasonably available
for inspection by Purchaser, any underwriter participating in any disposition
pursuant to the Registration Statement, and any attorney, accountant or other
agent retained by the Purchaser or any such underwriter all relevant financial
and other records, pertinent corporate documents and properties of the Company
and its subsidiaries, and cause the Company's officers, directors and employees
to supply all information reasonably requested by the Purchaser or any such
underwriter, attorney, accountant or agent in connection with the Registration
Statement, in each case, as is customary for similar due diligence examinations;
provided, however, that all records, information and documents that are
-------- --------
designated in writing by the Company, in good faith, as confidential,
proprietary or containing any material non-public information shall be kept
confidential by the Purchaser and any such underwriter, attorney, accountant or
agent (pursuant to an appropriate confidentiality agreement in the case of the
Purchaser, underwriter, attorney, accountant or agent), unless such disclosure
is made pursuant to judicial process in a court proceeding (after first giving
the Company an opportunity promptly to seek a protective order or otherwise
limit the scope of the information sought to be disclosed) or is required by
law, or such records, information or documents become available to the public
generally or through a third party not in violation of an accompanying
obligation of confidentiality; and provided further that, if the foregoing
                                   -------- -------
inspection and information gathering would otherwise disrupt the Company's
conduct of its business, such inspection and information gathering shall, to the
maximum extent possible, be coordinated on behalf of the Purchaser and the other
parties entitled thereto by one firm of counsel designed by and on behalf of the
majority in interest of Purchaser and other parties. The Company at its expense
will supply the Purchaser with copies of the Registration Statement and the
prospectus included therein and other related documents in such quantities as
may be reasonably requested by the Purchaser.

               (d) The Company shall not be required by this Section 3 to
include a Purchaser's Securities in any Registration Statement which is to be
filed if, in the opinion of counsel for both the Purchaser and the Company (or,
should they not agree, in the opinion of another counsel experienced in
securities law matters acceptable to counsel for the Purchaser and the Company)
the proposed offering or other transfer as to which such registration is
requested is exempt from applicable federal and state securities laws and would
result in all purchasers or transferees obtaining securities which are not
"restricted securities", as defined in Rule 144 under the Securities Act.

If at any time or from time to time after the effective date of the Registration
Statement, the Company notifies the Purchaser in writing of the existence of a
Blackout Event (as defined in Section 3(f) below), the Purchaser shall not offer
or sell any Securities or engage in any other transaction involving or relating
to Securities, from the time of the giving of notice with respect to a Blackout
Event until the Purchaser receives written notice from the Company that such
Blackout Event either has been disclosed in an effective post-effective
amendment to the Registration Statement or a valid prospectus supplement
thereto, or no longer constitutes a Blackout Event (the "Suspension Period");
provided, however, that, if a Suspension Period
--------  -------

                                       3
<PAGE>

occurs during any period commencing on a Trading Day a Draw Down Notice is
deemed delivered and ending three (3) Trading Days following the end of the
corresponding Draw Down Pricing Period, then (i) the Draw Down shall terminate
immediately, (ii) there shall be a prompt Settlement of any Draw Down which has
not yet settled but as to which the corresponding Draw Down Pricing Period ended
prior to the date the Purchaser is deemed to have received the Company's
Suspension Period notice, and, thereafter, no further Settlements relating to
the relevant Draw Down Notice shall occur, and (iii) the Company shall
compensate the Purchaser for any net decline in the market value of any
Securities purchased by the Purchaser pursuant to the relevant Draw Down Notice,
and not resold, through the end of such Suspension Period, but only to the
extent of actual losses suffered by the Purchaser as a result of such decline.
Net decline shall be calculated as the difference between the highest VWAP
during the applicable Suspension Period and the VWAP on the Trading Day
immediately following a properly delivered notice to the Purchaser that such
Suspension Period has ended. If a Blackout Event shall occur prior to the date
the Registration Statement is filed, then the Company's obligation to file the
Registration Statement shall be delayed without penalty for not more than thirty
(30) calendar days.

               (e) "Blackout Event" means any of the following: (a) the
possession by the Company of material information that is not ripe for
disclosure in a registration statement, as determined in good faith by the Chief
Executive Officer or the Board of Directors of the Company or that disclosure of
such information in the Registration Statement would be detrimental to the
business and affairs of the Company; or (b) any material engagement or activity
by the Company which would, in the good faith determination of the Chief
Executive Officer or the Board of Directors of the Company, be adversely
affected by disclosure in a registration statement at such time, which
determination shall be accompanied by a good faith determination by the Chief
Executive Officer or the Board of Directors of the Company that the Registration
Statement would be materially misleading absent the inclusion of such
information or (c) an occurrence, event or state of facts that results in the
Registration Statement no longer being current, and requiring action on the
Company's part in order to cause the prospectus forming a part of the
Registration Statement to meet the requirements of Section 5 of the Securities
Act.

               (f) In the event that the Company does not qualify to use Form
S-3 for the transactions contemplated by the Purchase Agreement at the time of
filing the Registration Statement, but subsequently becomes so qualified, the
Company shall promptly prepare and file a post-effective amendment to the
Registration Statement, so that, upon the effectiveness of such post-effective
amendment, the Registration Statement will become a registration statement on
Form S-3.

          Section 4.  Cooperation with Company.  Purchaser will cooperate with
                      ------------------------
the Company in all respects in connection with this Agreement, including timely
supplying all information reasonably requested by the Company (which shall
include all information regarding the Purchaser and proposed manner of sale of
the Registrable Securities required to be disclosed in the Registration
Statement) and executing and returning all documents reasonably requested in
connection with the registration and sale of the Registrable Securities.  The
Purchaser shall consent to be named as an underwriter in the Registration
Statement. Purchaser acknowledges

                                       4
<PAGE>

that in accordance with current Commission policy, the Purchaser will be named
as the underwriter of the Securities in the Registration Statement.

          Section 5.  Registration Procedures.  If and whenever the Company is
                      -----------------------
required by any of the provisions of this Agreement to effect the registration
of any of the Registrable Securities under the Act, the Company shall (except as
otherwise provided in this Agreement), as expeditiously as possible, subject to
the Purchaser's assistance and cooperation as reasonably required:

               (a) prepare and file with the Commission such amendments and
supplements to the Registration Statement and the prospectus used in connection
therewith as may be necessary to keep such registration statement effective and
to comply with the provisions of the Securities Act with respect to the sale or
other disposition of all securities covered by such registration statement
whenever the Purchaser of such Registrable Securities shall desire to sell or
otherwise dispose of the same (including prospectus supplements with respect to
the sales of securities from time to time in connection with a registration
statement pursuant to Rule 415 promulgated under the Securities Act) and (ii)
take all lawful action such that each of (A) the Registration Statement and any
amendment thereto does not, when it becomes effective, contain an untrue
statement of a material fact or omit to state a material fact required to be
stated therein or necessary to make the statements therein not misleading and
(B) the prospectus forming part of the Registration Statement, and any amendment
or supplement thereto, does not at any time during the Registration Period
include an untrue statement of a material fact or omit to state a material fact
required to be stated therein or necessary to make the statements therein, in
light of the circumstances under which they were made, not misleading;

               (b) prior to the filing with the Commission of any Registration
Statement (including any amendments thereto) and the distribution or delivery of
any prospectus (including any supplements thereto), provide draft copies thereof
to the Purchaser and reflect in such documents all such comments as the
Purchaser (and its counsel) reasonably may propose and (ii) furnish to the
Purchaser such numbers of copies of a prospectus including a preliminary
prospectus or any amendment or supplement to any prospectus, as applicable, in
conformity with the requirements of the Securities Act, and such other
documents, as the Purchaser may reasonably request in order to facilitate the
public sale or other disposition of the securities owned by the Purchaser.
Notwithstanding the foregoing, no prospectus supplement, the form of which has
previously been approved by the Purchaser, need be delivered in draft form to
the Purchaser;

               (c) promptly notify the Purchaser upon the occurrence of any of
the following events in respect of the Registration Statement or related
prospectus in respect of the Registrable Securities: (i) receipt of any request
for additional information from the SEC or any other federal or state
governmental authority during the period of effectiveness of the Registration
Statement the response to which would require any amendments or supplements to
the Registration Statement or related prospectus; (ii) the issuance by the SEC
or any other federal or state governmental authority of any stop order
suspending the effectiveness of the Registration Statement or the initiation of
any proceedings for that purpose; (iii) receipt of any notification with respect
to the suspension of the qualification or exemption from qualification of any of
the

                                       5
<PAGE>

Registrable Securities for sale in any jurisdiction or the initiation or
threatening of any proceeding for such purpose; (iv) the happening of any event
that makes any statement made in the Registration Statement or related
prospectus or any document incorporated or deemed to be incorporated therein by
reference untrue in any material respect or that requires the making of any
changes in the Registration Statement, related prospectus or documents so that,
in the case of the Registration Statement, it will not contain any untrue
statement of a material fact or omit to state any material fact required to be
stated therein or necessary to make the statements therein not misleading, and
that in the case of the related prospectus, it will not contain any untrue
statement of a material fact or omit to state any material fact required to be
stated therein or necessary to make the statements therein, in the light of the
circumstances under which they were made, not misleading; and (v) the Company's
reasonable determination that a post-effective amendment to the Registration
Statement would be appropriate; and the Company will promptly make available to
the Purchaser any such supplement or amendment to the related prospectus. The
Company shall not deliver to the Purchaser any Draw Down Notice during the
continuation of any of the foregoing events;

               (d) list such Registrable Securities on the Principal Market, and
any other exchange on which the Common Stock of the Company is then listed, if
the listing of such Registrable Securities is then permitted under the rules of
such exchange or the Nasdaq Stock Market;

               (e) cooperate with the Purchaser to facilitate the timely
preparation and delivery of certificates for the Registrable Securities to be
offered pursuant to the Registration Statement and enable such certificates for
the Registrable Securities to be in such denominations or amounts, as the case
may be, as the Purchaser reasonably may request and registered in such names as
the Purchaser may request; and, within three (3) Trading Days after a
Registration Statement which includes Registrable Securities is declared
effective by the Commission, deliver and cause legal counsel selected by the
Company to deliver to the transfer agent for the Registrable Securities (with
copies to the Purchaser whose Registrable Securities are included in such
Registration Statement) an appropriate instruction and, to the extent necessary,
an opinion of such counsel;

               (f) take all such other lawful actions reasonably necessary to
expedite and facilitate the disposition by the Purchaser of their Registrable
Securities in accordance with the intended methods therefor provided in the
prospectus which are customary for issuers to perform under the circumstances;
and

               (g) maintain a transfer agent for its Common Stock..

          Section 6.  Indemnification.
                      ---------------

               (a) The Company agrees to indemnify and hold harmless the
Purchaser and each person, if any, who controls the Purchaser within the meaning
of the Securities Act ("Distributing Purchaser") against any losses, claims,
damages or liabilities, joint or several (which shall, for all purposes of this
Agreement, include, but not be limited to, all reasonable costs of defense and
investigation and all reasonable attorneys' fees), to which the Distributing

                                       6
<PAGE>

Purchaser may become subject, under the Securities Act or otherwise, insofar as
such losses, claims, damages or liabilities (or actions in respect thereof)
arise out of or are based upon any untrue statement or alleged untrue statement
of any material fact contained in the Registration Statement, or any related
preliminary prospectus, final prospectus or amendment or supplement thereto, or
arise out of or are based upon the omission or alleged omission to state therein
a material fact required to be stated therein or necessary to make the
statements therein not misleading; provided, however, that the Company will not
be liable in any such case to the extent that any such loss, claim, damage or
liability arises out of or is based upon an untrue statement or alleged untrue
statement or omission or alleged omission made in the Registration Statement,
preliminary prospectus, final prospectus or amendment or supplement thereto in
reliance upon, and in conformity with, written information furnished to the
Company by the Distributing Purchaser specifically for use in the preparation
thereof. This Section 6(a) shall not inure to the benefit of any Distributing
Purchaser with respect to any person asserting such loss, claim, damage or
liability who purchased the Registrable Securities which are the subject thereof
if the Distributing Purchaser failed to send or give (in violation of the
Securities Act or the rules and regulations promulgated thereunder) a copy of
the prospectus contained in such Registration Statement to such person at or
prior to the written confirmation to such person of the sale of such Registrable
Securities, where the Distributing Purchaser was obligated to do so under the
Securities Act or the rules and regulations promulgated thereunder. This
indemnity agreement will be in addition to any liability which the Company may
otherwise have.

               (b) Each Distributing Purchaser agrees that it will indemnify and
hold harmless the Company, and each officer, director of the Company or person,
if any, who controls the Company within the meaning of the Securities Act,
against any losses, claims, damages or liabilities (which shall, for all
purposes of this Agreement, include, but not be limited to, all reasonable costs
of defense and investigation and all reasonable attorneys' fees) to which the
Company or any such officer, director or controlling person may become subject
under the Securities Act or otherwise, insofar as such losses, claims, damages
or liabilities (or actions in respect thereof) arise out of or are based upon
any untrue statement or alleged untrue statement of any material fact contained
in the Registration Statement, or any related preliminary prospectus, final
prospectus or amendment or supplement thereto, or arise out of or are based upon
the omission or the alleged omission to state therein a material fact required
to be stated therein or necessary to make the statements therein not misleading,
but in each case only to the extent that such untrue statement or alleged untrue
statement or omission or alleged omission was made in the Registration
Statement, preliminary prospectus, final prospectus or amendment or supplement
thereto in reliance upon, and in conformity with, written information furnished
to the Company by such Distributing Purchaser specifically for use in the
preparation thereof. This indemnity agreement will be in addition to any
liability which the Distributing Purchaser may otherwise have. Notwithstanding
anything to the contrary herein, the Distributing Purchaser shall not be liable
under this Section 6(b) for any amount in excess of the net proceeds to such
Distributing Purchaser as a result of the sale of Registrable Securities
pursuant to the Registration Statement.

               (c) Promptly after receipt by an indemnified party under this
Section 6 of notice of the commencement of any action, such indemnified party
will, if a claim in respect thereof is to be made against the indemnifying party
under this Section 6, notify the indemnifying

                                       7
<PAGE>

party of the commencement thereof; but the omission so to notify the
indemnifying party will not relieve the indemnifying party from any liability
which it may have to any indemnified party except to the extent of actual
prejudice demonstrated by the indemnifying party. In case any such action is
brought against any indemnified party, and it notifies the indemnifying party of
the commencement thereof, the indemnifying party will be entitled to participate
in, and, to the extent that it may wish, jointly with any other indemnifying
party similarly notified, assume the defense thereof, subject to the provisions
herein stated and after notice from the indemnifying party to such indemnified
party of its election so to assume the defense thereof, the indemnifying party
will not be liable to such indemnified party under this Section 6 for any legal
or other expenses subsequently incurred by such indemnified party in connection
with the defense thereof other than reasonable costs of investigation, unless
the indemnifying party shall not pursue the action to its final conclusion. The
indemnified party shall have the right to employ separate counsel in any such
action and to participate in the defense thereof, but the fees and expenses of
such counsel shall not be at the expense of the indemnifying party if the
indemnifying party has assumed the defense of the action with counsel reasonably
satisfactory to the indemnified party; provided that if the indemnified party is
the Distributing Purchaser, the fees and expenses of such counsel shall be at
the expense of the indemnifying party if (i) the employment of such counsel has
been specifically authorized in writing by the indemnifying party, or (ii) the
named parties to any such action (including any impleaded parties) include both
the Distributing Purchaser and the indemnifying party and the Distributing
Purchaser shall have been advised by such counsel that there may be one or more
legal defenses available to the indemnifying party different from or in conflict
with any legal defenses which may be available to the Distributing Purchaser (in
which case the indemnifying party shall not have the right to assume the defense
of such action on behalf of the Distributing Purchaser, it being understood,
however, that the indemnifying party shall, in connection with any one such
action or separate but substantially similar or related actions in the same
jurisdiction arising out of the same general allegations or circumstances, be
liable only for the reasonable fees and expenses of one separate firm of
attorneys for the Distributing Purchaser, which firm shall be designated in
writing by the Distributing Purchaser and be approved by the indemnifying
party). No settlement of any action against an indemnified party shall be made
without the prior written consent of the indemnified party, which consent shall
not be unreasonably withheld.

          All fees and expenses of the indemnified party (including reasonable
costs of defense and investigation in a manner not inconsistent with this
Section and all reasonable attorneys' fees and expenses) shall be paid to the
indemnified party, as incurred, within ten (10) Trading Days of written notice
thereof to the indemnifying party; provided, that the indemnifying party may
require such indemnified party to undertake to reimburse all such fees and
expenses to the extent it is finally judicially determined that such indemnified
party is not entitled to indemnification hereunder).

          Section 7.  Contribution.  In order to provide for just and equitable
                      ------------
contribution under the Securities Act in any case in which (i) the indemnified
party makes a claim for indemnification pursuant to Section 6 hereof but is
judicially determined (by the entry of a final judgment or decree by a court of
competent jurisdiction and the expiration of time to appeal or the denial of the
last right of appeal) that such indemnification may not be enforced in such case
notwithstanding the fact that the express provisions of Section 6 hereof provide
for

                                       8
<PAGE>

indemnification in such case, or (ii) contribution under the Securities Act
may be required on the part of any indemnified party, then the Company and the
applicable Distributing Purchaser shall contribute to the aggregate losses,
claims, damages or liabilities to which they may be subject (which shall, for
all purposes of this Agreement, include, but not be limited to, all reasonable
costs of defense and investigation and all reasonable attorneys' fees), in
either such case (after contribution from others) on the basis of relative fault
as well as any other relevant equitable considerations.  The relative fault
shall be determined by reference to, among other things, whether the untrue or
alleged untrue statement of a material fact or the omission or alleged omission
to state a material fact relates to information supplied by the Company on the
one hand or the applicable Distributing Purchaser on the other hand, and the
parties' relative intent, knowledge, access to information and opportunity to
correct or prevent such statement or omission.   The Company and the
Distributing Purchaser agree that it would not be just and equitable if
contribution pursuant to this Section 7 were determined by pro rata allocation
or by any other method of allocation which does not take account of the
equitable considerations referred to in this Section 7.  The amount paid or
payable by an indemnified party as a result of the losses, claims, damages or
liabilities (or actions in respect thereof) referred to above in this Section 7
shall be deemed to include any legal or other expenses reasonably incurred by
such indemnified party in connection with investigating or defending any such
action or claim. No person guilty of fraudulent misrepresentation (within the
meaning of Section 11(f) of the Securities Act) shall be entitled to
contribution from any person who was not guilty of such fraudulent
misrepresentation.

          Notwithstanding any other provision of this Section 7, in no event
shall any Purchaser be required to undertake liability to any person under this
Section 7 for any amounts in excess of the dollar amount of the net proceeds to
be received by the Purchaser from the sale of the Purchaser's Registrable
Securities (after deducting any fees, discounts and commissions applicable
thereto) pursuant to any Registration Statement under which such Registrable
Securities are to be registered under the Securities Act.

          Section 8.  Notices.  All notices, demands, requests, consents,
                      -------
approvals, and other communications required or permitted hereunder shall be in
writing and, unless otherwise specified herein, shall be delivered as set forth
in the Purchase Agreement.

          Section 9.  Assignment.  Neither this Agreement nor any rights of the
                      ----------
Purchaser or the Company hereunder may be assigned by either party to any other
person. Notwithstanding the foregoing, (a) the provisions of this Agreement
shall inure to the benefit of, and be enforceable by, any transferee of any of
the Common Stock purchased by the Purchaser pursuant to the Purchase Agreement
other than through open-market sales,  (b) upon the prior written consent of the
Company, which consent shall not be unreasonably withheld or delayed in the case
of an assignment to an affiliate of the Purchaser, the Purchaser's interest in
this Agreement may be assigned at any time, in whole or in part, to any other
person or entity (including any affiliate of the Purchaser) who agrees to be
bound hereby and (c) the Company may, without the consent of the Purchaser,
assign its rights and obligations under this Agreement to any person or entity
that controls, is controlled by or is under common control with the Company, and
the provisions hereof will inure to the benefit of and be binding upon each

                                       9
<PAGE>

successor of the Company, whether by merger, consolidation, transfer of all or
substantially all assets, or otherwise.

          Section 10.  Counterparts/Facsimile.  This Agreement may be executed
                       ----------------------
in two or more counterparts, each of which shall constitute an original, but all
of which, when together shall constitute but one and the same instrument, and
shall become effective when one or more counterparts have been signed by each
party hereto and delivered to the other party.  In lieu of the original, a
facsimile transmission or copy of the original shall be as effective and
enforceable as the original.

          Section 11.  Remedies and Severability.  The remedies provided in this
                       -------------------------
Agreement are cumulative and not exclusive of any remedies provided by law.  If
any term, provision, covenant or restriction of this Agreement is held by a
court of competent jurisdiction to be invalid, illegal, void or unenforceable,
the remainder of the terms, provisions, covenants and restrictions set forth
herein shall remain in full force and effect and shall in no way be affected,
impaired or invalidated, and the parties hereto shall use their best efforts to
find and employ an alternative means to achieve the same or substantially the
same result as that contemplated by such term, provision, covenant or
restriction.  It is hereby stipulated and declared to be the intention of the
parties that they would have executed the remaining terms, provisions, covenants
and restrictions without including any of such that may be hereafter declared
invalid, illegal, void or unenforceable.

          Section 12.  Conflicting Agreements.  The Company shall not enter into
                       ----------------------
any agreement with respect to its securities that is inconsistent with the
rights granted to the holders of Registrable Securities in this Agreement or
otherwise prevents the Company from complying with all of its obligations
hereunder.

          Section 13.  Headings.  The headings in this Agreement are for
                       --------
reference purposes only and shall not affect in any way the meaning or
interpretation of this Agreement.

          Section 14.  Governing Law.  This Agreement shall be governed by and
                       -------------
construed in accordance with the laws of the State of California applicable to
contracts made in California by persons domiciled in California and without
regard to its principles of conflicts of laws. Any action may be brought as set
forth in the Purchase Agreement.  Any party shall have the right to seek
injunctive relief from any court of competent jurisdiction in any case where
such relief is available.  Any dispute under this Agreement shall be submitted
to arbitration under the American Arbitration Association (the "AAA") in New
York City, New York, and shall be finally and conclusively determined by the
decision of a board of arbitration consisting of three (3) members (hereinafter
referred to as the "Board of Arbitration") selected as according to the rules
governing the AAA.  The Board of Arbitration shall meet on consecutive business
days in New York City, New York, and shall reach and render a decision in
writing (concurred in by a majority of the members of the Board of Arbitration)
with respect to the amount, if any, which the losing party is required to pay to
the other party in respect of a claim filed.  In connection with rendering its
decisions, the Board of Arbitration shall adopt and follow the laws of the State
of New York.  To the extent practical, decisions of the Board of Arbitration
shall be rendered no more than thirty (30) calendar days following commencement
of proceedings with respect thereto. The Board of

                                       10
<PAGE>

Arbitration shall cause its written decision to be delivered to all parties
involved in the dispute. The Board of Arbitration shall be authorized and is
directed to enter a default judgment against any party refusing to participate
in the arbitration proceeding within thirty days of any deadline for such
participation. Any decision made by the Board of Arbitration (either prior to or
after the expiration of such thirty (30) calendar day period) shall be final,
binding and conclusive on the parties to the dispute, and entitled to be
enforced to the fullest extent permitted by law and entered in any court of
competent jurisdiction. The prevailing party shall be awarded its costs,
including attorneys' fees, from the non-prevailing party as part of the
arbitration award. Any party shall have the right to seek injunctive relief from
any court of competent jurisdiction in any case where such relief is available.
The prevailing party in such injunctive action shall be awarded its costs,
including attorney's fees, from the non-prevailing party.

                                       11
<PAGE>

          IN WITNESS WHEREOF, the parties hereto have caused this Registration
Rights Agreement to be duly executed as of the date first above written.

                                        HOLLIS-EDEN PHARMACEUTICALS, INC.

                                        By:________________________________

                                        BALLSBRIDGE FINANCE LTD.

                                        By:________________________________
                                             Name:
                                             Title:

                                       12

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