Document:

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                                                                  Execution Copy

                       OPTOPICS LABORATORIES CORPORATION

                                    - and -

                        MIZA PHARMACEUTICALS USA, INC.

                           ASSET PURCHASE AGREEMENT

                               OCTOBER 14, 1999

                                 Bennett Jones
                           1000, 10035 - 105 Street
                               Edmonton, Alberta
                                    T5J 3T2
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                               TABLE OF CONTENTS

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                                   ARTICLE I
                                INTERPRETATION

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1.1      DEFINED TERMS..................................................    1

1.2      GENDER AND NUMBER..............................................    8

1.3      HEADINGS ETC...................................................    8

1.4      CURRENCY.......................................................    8

1.5      SEVERABILITY...................................................    8

1.6      ENTIRE AGREEMENT...............................................    9

1.7      AMENDMENTS.....................................................    9

1.8      STATUTORY REFERENCES...........................................    9

1.9      WAIVER.........................................................    9

1.10     GOVERNING LAW..................................................    9

1.11     INCLUSION......................................................    9

1.12     ACCOUNTING.....................................................    9

1.13     CONSENT........................................................    9

1.14     CALCULATION OF TIME............................................   10

1.15     BUSINESS DAY...................................................   10

1.16     INCORPORATION OF SCHEDULES.....................................   10

                                  ARTICLE II
                                    ASSETS

2.1      ASSETS.........................................................   11

2.2      ASSIGNMENT OF CONTRACTS........................................   12

2.3      [INTENTIONALLY OMITTED]........................................   12

2.4      GRANT OF KNOW-HOW AND OTHER INTELLECTUAL PROPERTIES............   12

                                  ARTICLE III
                                PURCHASE PRICE

3.1      PURCHASE PRICE.................................................   12

3.2      ALLOCATION.....................................................   12

3.3      PAYMENT AT CLOSING.............................................   13

3.4      [INTENTIONALLY OMITTED.].......................................   13
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3.5      PAYMENT OF SALES TAX AND REGISTRATION CHARGES ON TRANSFER......  13

                                  ARTICLE IV
                              ASSUMED LIABILITIES

4.1      ASSUMED LIABILITIES............................................  13

4.2      EXCLUDED LIABILITIES...........................................  13

4.3      ASSUMPTION OF CONTRACTUAL LIABILITIES..........................  14

                                   ARTICLE V
                 REPRESENTATIONS AND WARRANTIES OF THE VENDOR

5.1      DUE CONSTITUTION OF THE VENDOR.................................  14

5.2      POWER..........................................................  14

5.3      QUALIFICATION TO DO BUSINESS...................................  14

5.4      VALIDITY OF AGREEMENT..........................................  14

5.5      RESTRICTIVE DOCUMENTS..........................................  15

5.6      COMMERCIAL RELATIONSHIPS.......................................  15

5.7      NO MATERIAL ADVERSE CHANGE.....................................  15

5.8      COMPLIANCE WITH LAWS...........................................  16

5.9      AUTHORIZATIONS.................................................  16

5.10     TITLE TO ASSETS................................................  17

5.11     NO OPTIONS ON ASSETS, ETC......................................  17

5.12     CONDITION OF INVENTORIES.......................................  17

5.13     REAL PROPERTY..................................................  17

5.14     LEASE..........................................................  17

5.15     MATERIAL CONTRACTS.............................................  18

5.16     CONSENTS.......................................................  18

5.17     NO BREACH OF CONTRACTS.........................................  18

5.18     INTELLECTUAL PROPERTY RIGHTS...................................  18

5.19     BOOKS AND RECORDS..............................................  19

5.20     TAXES..........................................................  19

5.21     EMPLOYEES......................................................  19

5.22     ENVIRONMENTAL MATTERS..........................................  20

5.23     INSURANCE......................................................  21

5.24     LITIGATION.....................................................  21
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5.25     WARRANTIES.....................................................  21

5.26     YEAR 2000 COMPLIANCE...........................................  21

                                  ARTICLE VI
                REPRESENTATIONS AND WARRANTIES OF THE PURCHASER

6.1      DUE INCORPORATION AND EXISTENCE OF THE PURCHASER...............  22

6.2      VALIDITY OF AGREEMENT..........................................  22

6.3      RESTRICTIVE DOCUMENTS..........................................  22

                                  ARTICLE VII
                     PRE-CLOSING COVENANTS OF THE PARTIES

7.1      OPERATION OF ASSETS PRIOR TO CLOSING...........................  22

7.2      ACTIONS TO SATISFY CLOSING CONDITIONS..........................  24

7.3      TRANSFER OF THE ASSETS.........................................  25

7.4      REQUEST FOR CONSENTS...........................................  25

7.5      FILINGS AND AUTHORIZATIONS.....................................  25

7.6      BULK SALES LAWS................................................  25

7.7      NOTICE OF UNTRUE REPRESENTATION OR WARRANTY....................  25

7.8      EXCLUSIVE DEALING..............................................  25

                                 ARTICLE VIII
                             CONDITIONS OF CLOSING

8.1      CONDITIONS FOR THE BENEFIT OF THE PURCHASER....................  26

8.2      NON-PERFORMANCE BY VENDOR......................................  28

8.3      CONDITIONS FOR THE BENEFIT OF THE VENDOR.......................  28

8.4      NON-PERFORMANCE BY PURCHASER...................................  29

8.5      MUTUAL CONDITIONS PRECEDENT....................................  30

                                  ARTICLE IX
                  CLOSING, TRANSFER OF POSSESSION, RISK OF LOSS

9.1      DATE, TIME AND PLACE OF CLOSING................................  30

9.2      CLOSING PROCEDURES.............................................  30

9.3      RISK OF LOSS...................................................  31

                                   ARTICLE X
            SURVIVAL OF REPRESENTATIONS AND WARRANTIES; INDEMNITIES

10.1     SURVIVAL OF REPRESENTATIONS AND WARRANTIES.....................  31
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10.2     INDEMNIFICATION IN FAVOUR OF THE PURCHASER..................... 31

10.3     INDEMNIFICATION IN FAVOUR OF THE VENDOR........................ 32

10.4     INDEMNIFICATION PROCEEDINGS.................................... 32

10.5     EXCLUSION OF OTHER REMEDIES.................................... 34

                                  ARTICLE XI
                            POST-CLOSING COVENANTS

11.1     ADDITIONAL MATTERS............................................. 34

11.2     FURTHER ASSURANCES............................................. 34

                                  ARTICLE XII
                            [INTENTIONALLY OMITTED]

                                 ARTICLE XIII
                                   EMPLOYEES

13.1     TERMS OF EMPLOYMENT............................................ 35

13.2     TERMINATION OF EMPLOYEES....................................... 35

13.3     OFFER OF EMPLOYMENT............................................ 35

13.4     INDEMNIFICATION BY VENDOR...................................... 35

                                   ARTICLE XIV
                       NON-COMPETITION AND CONFIDENTIALITY

14.1     NON-COMPETITION AND CONFIDENTIALITY............................ 35

14.2     LIMITATIONS.................................................... 36

14.3     NON-USE OF TRADE MARKS......................................... 36

14.4     MODIFICATION................................................... 36

                                  ARTICLE XV
                            RESOLUTION OF DISPUTES

15.1     RESOLUTION OF DISPUTES......................................... 36

ARTICLE XVI
                                 MISCELLANEOUS

16.1     NOTICES........................................................ 37

16.2     PUBLICITY...................................................... 38

16.3     TIME OF THE ESSENCE............................................ 38

16.4     BROKERS........................................................ 38

16.5     THIRD PARTY BENEFICIARIES...................................... 39
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16.6     EXPENSES....................................................... 39

16.7     ENUREMENT...................................................... 39

16.8     ASSIGNMENT..................................................... 39

16.9     COUNTERPARTS................................................... 39

16.10    NON-MERGER..................................................... 40
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                                                                  Execution Copy

                           ASSET PURCHASE AGREEMENT

This Agreement made the 14/th/ day of October, 1999

BETWEEN:

          OPTOPICS LABORATORIES CORPORATION, a body corporate,
          incorporated under the laws of the State of Delaware
          and having offices at Fairton, New Jersey, USA (the
          "Vendor")

                                    - and -

          MIZA PHARMACEUTICALS USA, INC., a body corporate,
          incorporated under the laws of the State of Delaware
          and having offices at Boston, Massachusetts (the
          "Purchaser")

WHEREAS the Vendor carries on a sterile liquid drug manufacturing business from
facilities in the State of New Jersey, USA; and

WHEREAS the Vendor desires to sell to the Purchaser and the Purchaser desires to
purchase from the Vendor, in accordance with the terms of this Agreement,
certain of the property and assets used in the operation of the aforesaid
business of the Vendor;

NOW THEREFORE in consideration of the premises and the mutual agreements
contained in this Agreement, and of other valuable consideration (the receipt
and adequacy of which are hereby acknowledged) the Parties hereto agree as
follows:

                                   ARTICLE I
                                INTERPRETATION

1.1  Defined Terms

In this Agreement, including the premises hereto, this Section and each
Schedule, the following terms have the following meanings:

"Accounts Payable" means all trade and other accounts payable and accruals or
amounts otherwise payable by the Vendor, including payables to Affiliates, in
connection with the Business and the operation of the Assets;

"Accounts Receivable" means all trade and other accounts receivable, notes
receivable and other debts due or accruing due to the Vendor in connection with
the Business;

"Affiliate" means, with respect to any Person, any other Person which directly
or indirectly controls, is controlled by or is under control with the specified
Person;
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"Agreement" means this asset purchase agreement and all schedules and
instruments in amendment or confirmation of it, "hereof", "hereto" and
"hereunder" and similar expressions mean and refer to this Agreement and not to
any particular Article, Section, Subsection or other subdivision and "Article",
"Section", "Subsection", "Paragraph" or other subdivision followed by a number
means and refers to the specified Article, Section, Subsection, Paragraph or
other subdivision of this Agreement;

"Agreement of Sale" means the agreement between Fairton Realty Holdings, Inc.
and the Purchaser substantially in the form of the unexecuted agreement attached
hereto as Schedule 1.1(a);

"Ancillary Agreements" means all agreements, certificates and other instruments
delivered or given pursuant to this Agreement, including the Closing Agreements;
and "Ancillary Agreement" means any one of such agreements, certificates or
other instruments;

"aNDAs" means the abbreviated new drug applications in the name of the Vendor or
NutraMax used in the Business;

"Assets" means the assets listed in Section 2.1(a) to (l) inclusively but
excluding the Excluded Assets;

"Assumed Liabilities" has the meaning ascribed thereto in Section 4.1;

"Authorization" means, with respect to any Person, any authorization, order,
permit, approval, grant, licence, consent, right, franchise, privilege,
certificate, judgment, writ, injunction, award, determination, direction, decree
or by-law, rule or regulation of any Governmental Entity having jurisdiction
over such Person, whether or not having the force of Law;

"Benefit Plans" means the employee benefit plans relating to the employees of
the Business which are listed as benefit plans in Schedule 1.1(c);

"Books and Records" means all technical and business records, data, reports,
files, lists, drawings, art work, graphic arts files and films, plans, logs,
briefs, customer and supplier lists, deeds, certificates, contracts, surveys, or
any other documentation and information in any form whatsoever (including
written, printed, electronic or computer printout form) in respect of the
Assets;

"Buildings and Fixtures" means all plant, buildings, structures, erections,
improvements, appurtenances and fixtures (including fixed machinery and fixed
equipment) situated at the Plant, the Owned Property or the Leased Property, or
all of them as the context requires;

"Business" means the sterile liquid drug manufacturing business carried on by
the Vendor from the Plant and the Warehouse;

"Business Day" means any day of the year, other than a Saturday, Sunday or any
day on which banks are generally required or authorized to close in Edmonton,
Alberta, Canada or in Fairton, New Jersey, USA;
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                                      -3-

"Claim" means any claim of any nature whatsoever, including any demand,
liability, obligation, debt, cause of action, suit, proceeding, judgment, award,
assessment and reassessment;

"Closing" means the completion of the transaction of purchase and sale and other
transactions contemplated in this Agreement;

"Closing Agreements" means, collectively, the Agreement of Sale, the NutraMax
Guarantee, the MIZA Guarantee and the Distribution Agreement;

"Closing Date" means a date during the week of November 15, 1999 or such other
date upon which the Parties may mutually agree in writing;

"Collective Bargaining Agreements" means collective bargaining agreements
between the Vendor and one or more unions representing employees of the Vendor;

"Consents" means the consents of contracting parties required for the assignment
of any Contract or Lease, and "Consent" means any one of such Consents;

"Contracts" means the contracts, agreements in respect of Intellectual
Properties, leases of real and personal property, licenses, undertakings,
engagements or commitments listed in Schedule 2.1(c) and "Contract" means any
one of such Contracts;

"Contractual Rights" has the meaning ascribed thereto in Section 2.2;

"Dealing" means any past, present or future activity, event or circumstance in
respect of a Substance, including using, generating, manufacturing, refining,
treating, transporting, storing, handling, labelling, documenting, recycling,
disposing of, depositing, transferring, producing or processing the Substance or
contracting to do any of the foregoing;

"Discharge", in respect of a Substance, includes any emission, discharge,
release, deposit, issuance, spray, injection, abandonment, escape, spill, leak,
seepage, disposal, exhaust, or as defined in any Environmental Laws of the
United States of America or the State of New Jersey, of such Substance;

"Distribution Agreement" means the shipping and distribution agreement among the
Vendor, the Purchaser and NutraMax substantially in the form of unexecuted
agreement attached hereto as Schedule 1.1(e);

"Effective Time" means 11:59 p.m. (Fairton time) on the Closing Date;

"Employees" means the employees of the Vendor immediately before Closing who are
listed on Schedule 1.1(d) hereto;

"Encumbrances" means liens, charges, mortgages, pledges, security interests,
claims, defects of title, restrictions, leases and any other rights of third
parties relating to property, including rights of set-off, voting trusts and
other encumbrances of any kind;

"Environment" includes the ambient air, all layers of atmosphere, surface water,
underground water, any land or underground space even if submerged in water or
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                                      -4-

covered by a structure, all organic and inorganic matters, all living organisms
and the interacting natural systems that include components of air, land, water,
organic and inorganic matters and living organisms;

"Environmental Laws" includes all federal, state, municipal or local statutes,
regulations, by-laws, guidelines, policies or rules, and orders of any
Governmental Entity, relating to the Environment, applicable to the Assets, the
Owned Property or the Leased Property;

"Environmental Liabilities and Costs" means all Losses and Claims relating to
the Environment, whether known or unknown, current or potential, past, present
or future, including those imposed by, under or pursuant to Environmental Laws,
all Losses and Claims related to Remedial Actions and all reasonable fees,
disbursements and expenses of counsel, experts, personnel and consultants, where
such Losses and Claims relating to the Environment are based on, arise out of or
are otherwise in respect of:

     (a)  the ownership or operation of the Assets;

     (b)  the conditions on, under, above or about any real property, assets,
          equipment or facilities currently or previously owned, leased or
          operated by the Vendor;

     (c)  expenditures necessary to cause the operations of any of the Assets to
          comply in all material respects with any and all requirements under
          Environmental Laws, including expenditures in connection with
          obtaining required Environmental Permits;

     (d)  expenditures necessary to effect the closure, decommissioning or
          rehabilitation of any of the operations of any of the Assets owned,
          leased or operated by the Vendor;

     (e)  liability for personal injury or property damage, including damages
          assessed for the maintenance of a public or private nuisance; and

     (f)  any other matter affecting [the Owned Properties], Leased Property or
          other Assets within the jurisdiction of any Governmental Entity
          administering any Environmental Law;

"Environmental Permits" means all permits, certificates, approvals,
registrations and licences issued or issuable by any Governmental Entity
pursuant to any Environmental Law;

"Environmental Reports" includes all environmental audits, environmental
compliance reviews, environmental site assessments and all studies or
evaluations relating to the Environment prepared by or on behalf of the Vendor
in respect of the operation of the Assets;

"Excluded Assets" means (a) all cash or Accounts Receivable; (b) corporate books
and records of NutraMax, as well as those of the Vendor and Fairton, as they
relate to sensitive financial or strategic matters pertaining principally to the
business of
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                                      -5-

NutraMax; and (c) any assets, contractual rights and obligations not
specifically described in this Agreement or schedules attached hereto;

"Excluded Liabilities" has the meaning ascribed thereto in Section 4.2;

"Fairton" means Fairton Realty Holdings Inc.;

"GAAP" means generally accepted accounting principles so described and
promulgated by the American Institute of Certified Public Accountants and
applied on a basis which is consistent with the past practice of the Vendor;

"Governmental Entity" means (i) any multinational, federal, state, municipal,
local or other governmental or public department, court, commission, board,
bureau, agency or instrumentality, domestic or foreign; (ii) any subdivision,
agent, commission, board or authority of any of the foregoing; or (iii) any
quasi-governmental or private body exercising any regulatory, expropriation or
taxing authority under or for the account of any of the foregoing;

"Intellectual Properties" means any and all Trade Marks, Know-How, copyrights,
applications for any of the foregoing, designs, inventions, computer programs
and other intellectual or industrial property related to the operation of the
Assets including all aNDAs, all as described in Schedule 2.1(d);

"Interim Period" means the period of time between the close of business on
August 31, 1999 and the Time of Closing on the Closing Date;

"Inventories" means all inventories of raw materials, packaging materials and
finished products of the Business excluding Materials in Processing;

"Know-How" means technical know-how, data, information, recipes, formulae and
processes including standard operating procedures, research and development
know-how and manufacturing know-how such as plant designs and operating manuals
related to the Assets and the operation of the Assets in the possession or
control of the Vendor or of NutraMax;

"Laws" means all statutes, codes, ordinances, decrees, rules, regulations,
municipal ordinances, judicial or arbitral or administrative or ministerial or
departmental or regulatory judgments, orders, decisions, rulings or awards, or
any provisions of the foregoing, including general principles of common law and
equity, binding on or affecting the Person referred to in the context in which
such word is used; and "Law" means any one of them;

"Leased Property", when used in respect of the Vendor, means the lands and
premises forming the subject matter of the Lease from which the Vendor carries
on the Business at the municipal addresses as listed in Schedule 1.1(g);

"Lease", when used in respect of the Vendor, means the lease and sublease of
lands and premises used in the Business which is listed and described in
Schedule 1.1(g);

"Loss" means any loss whatsoever, including expenses, costs, damages, diminution
in value, penalties, fines, charges, claims, demands, liabilities, interest and
any and all legal fees and disbursements;
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                                      -6-

"Machinery and Equipment" means machinery, computer equipment, other equipment,
jigs, dies, tools, handling equipment, furniture and furnishings used in
connection with the Business;

"Materials in Processing" means raw materials, packaging materials and finished
products in processing at the Plant;

"MIZA Guarantee" means the guarantee agreement between MIZA Pharmaceuticals,
Inc. and the Vendor substantially in the form of the unexecuted agreement
attached hereto as Schedule 1.1(h);

"Notice" means any claim, citation, directive, order (draft or otherwise),
request for information, statement of claim, litigation, notice of
investigation, investigation, proceeding, judgment, letter or other
communication, written or oral, actual or implied or threatened, from any
Person;

"NutraMax" means NutraMax Products, Inc., the parent corporation of the Vendor;

"NutraMax Guarantee" means the guarantee agreement between NutraMax and the
Purchaser substantially in the form of the unexecuted agreement attached hereto
as Schedule 1.1(i);

"Owned Property", when used in respect of the Vendor, means, collectively, the
lands and premises which are listed and described as such in Schedule 1.1(j) and
the Buildings and Fixtures thereon;

"Parties" means the Vendor, the Purchaser and any other person who may become a
party to this Agreement; and "Party" means any one of them;

"Pension Plan" means a pension plan administered by the Vendor for the benefit
of employees of the Business other than the 401K plan or profit sharing plan
administered by the Vendor;

"Permitted Encumbrances" means (a) Encumbrances for Taxes, assessments or
governmental charges or levies on property not yet due and delinquent; (b)
easements, encroachments and other minor imperfections of title which do not
individually or in the aggregate materially detract from the value of, or impair
the use or marketability of any real property or the Assets; and (c) the
Encumbrances listed in Schedule 1.1(j);

"Person" means an individual, partnership, corporation, trust, unincorporated
association, joint venture or other entity or Governmental Entity, and pronouns
have a similarly extended meaning;

"Plant" means the sterile liquid drug manufacturing plant situated at 32 Main
Street, Fairton, New Jersey, USA;

"Prime" means the floating annual rate of interest established and announced by
the Wall Street Journal from time to time as a reference rate for the purpose of
determining rates of interest charged on loans denominated in US dollars;

"Purchase Price" has the meaning ascribed thereto in Section 3.1;
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"Remedial Action" means any action, whether voluntary or compelled, that is
reasonably necessary to (a) clean up, remove, treat or in any other way deal
with Substances in the Environment; (b) prevent any Discharge of Substances
where such Discharge would violate any Environmental Laws or would endanger or
threaten to endanger public health or welfare or the Environment; or (c) perform
remedial studies, investigations, restoration and post-remedial studies,
investigations and monitoring on, about or in connection with any of the Assets;

"Restricted Business" means the Business as conducted by the Vendor immediately
prior to Closing, but not including any pharmaceutical manufacturing using
blow/fill/seal technology including the manufacturing of ophthalmic products;

"Spare Parts" means accessories, supplies and processing materials stored at the
Plant to be used in connection with the operation of the Assets;

"Substance" means any material or substance that is deemed to be "hazardous",
"toxic", "deleterious", "caustic", "dangerous", a "contaminant", a "waste", a
"source of contaminant" or a "pollutant" under any Environmental Laws of the
United States or the State of New Jersey applicable to the Assets, the Owned
Property or the Leased Property;

"Tax" means any tax, duty, excise, fee, impost, assessment, deduction, charge or
withholding tax including federal and state sales tax, social services tax,
goods and services tax, land transfer tax, property purchase tax, income taxes,
excise tax, use tax, business tax, capital tax, franchise tax and other state
and federal taxes, municipal tax, local tax, foreign tax, and all liabilities
with respect thereto, including any penalty and interest payable with respect
thereto, levied, imposed or assessed from time to time upon or in respect of
income, profits or assets of any nature or kind by any Governmental Entity;

"Third Party/Third Parties" means all persons or entities with which the Vendor
deals, or upon which it depends, directly or indirectly, in satisfying its
obligations of the Business without delay or interruption;

"Time of Closing" means 10:00 a.m. (Gloucester, MA time) on the Closing Date or
such later time as the completion of the transaction of purchase and sale
contemplated in this Agreement may occur;

"Trade Mark" means any and all trade mark registrations and applications for
trade mark registrations and brand names related to the Assets in the name of
the Vendor or NutraMax;

"Transferred Employee" means an Employee who has accepted an offer of employment
from the Purchaser;

"Vendor's Group" means the Vendor and NutraMax;

"Warehouse" means the leased warehouse situated at 176 Baltimore Avenue,
Bridgeton, New Jersey, USA also hereinafter referred to as the Leased Property;
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                                      -8-

"Year 2000 Compliant/Year 2000 Compliance" means the state where all products
and systems containing date-recording or date sensitive electronic components
and used, directly or indirectly, to satisfy obligations under this Agreement,
whether owned or used by the Vendor or a Third Party (a) are designed to be used
and will, correctly and without human intervention, store, record, process, use,
calculate, sequence and exchange data which references dates prior to, during
and after the calendar year 2000 A.D. without error relating to date data, and
will operate transparently to the user during such time periods without a
difference in functionality or performance; (b) are capable of operating without
error relating to logical and mathematical operations carried out on date data
which represents or references different centuries or more than one century; (c)
correctly recognize the year 2000 as a leap year; (d) do not use date fields as
indicators or for purposes other than to store valid dates; (e) will not
experience any interruption, malfunction or failure as a result of any value of
current date; and (f) are designed such that the century in all date fields,
date-related user interfaces and other interfaces is specified either explicitly
or by unambiguous algorithms or inferencing rules (and that, in the latter case,
the products or systems respond to two-digit year dates in a way that resolves
the ambiguity as to the century in a disclosed, defined and pre-determined
manner); and

"Year 2000 Problem" means any matter that affects or may affect, temporarily or
permanently, the present or future ability of products or systems to be Year
2000 Compliant.

1.2  Gender and Number

Any reference in this Agreement to gender shall include all genders, and words
importing the singular number only shall include the plural and vice versa.

1.3  Headings Etc.

The provision of a Table of Contents, the division into Articles, Sections,
Subsections and other subdivisions and the insertion of headings are for
convenience of reference only and shall not affect or be utilized in the
construction or interpretation of this Agreement.

1.4  Currency

All references in this Agreement to dollars, unless otherwise specifically
indicated, are expressed in US currency.

1.5  Severability

Any Article, Section, Subsection or other subdivision of the Agreement or any
other provision of this Agreement which is, or becomes, illegal, invalid or
unenforceable shall be severed from this Agreement and be ineffective to the
extent of such illegality, invalidity or unenforceability and shall not affect
or impair the remaining provisions hereof, which provisions shall remain in full
force and effect.
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1.6   Entire Agreement

This Agreement together with the Ancillary Agreements constitutes the entire
agreement between the Parties relating to the subject matter hereof and
supersedes all prior agreements, understandings, negotiations and discussions,
whether oral or written, of the Parties. There are no representations,
warranties, conditions or other agreements, express or implied, statutory or
otherwise, between the Parties in connection with the subject matter of this
Agreement, except as specifically set forth herein and therein. If there is any
conflict between the provisions of this Agreement and the provisions of any
Ancillary Agreement, the provisions of this Agreement shall govern.

1.7   Amendments

This Agreement may only be amended, modified or supplemented by a written
agreement signed by all Parties.

1.8   Statutory References

Any reference in this Agreement to a statute includes all regulations made
thereunder, all amendments to such statutes or regulations in force from time to
time, and any statute or regulation that supplements or supersedes such statute
or regulations.

1.9   Waiver

No waiver of any of the provisions of this Agreement shall be deemed to
constitute a waiver of any other provision (whether or not similar), nor shall
such waiver constitute a waiver or continuing waiver unless otherwise expressly
provided in writing duly executed by the Party to be bound thereby.

1.10  Governing Law

This Agreement shall be governed by and interpreted and enforced in accordance
with the laws of the State of New Jersey.

1.11  Inclusion

Where the word "including" or "includes" is used in this Agreement it means
"including (or includes) without limitation".

1.12  Accounting

All accounting terms used in this Agreement and not specifically defined herein
or therein shall be construed in accordance with GAAP.

1.13  Consent

Whenever a provision of this Agreement requires an approval or consent by a
Person who is a party to an agreement and notification of such approval or
consent is not delivered within the applicable time period, then, unless
otherwise specified, such Person shall be conclusively deemed to have withheld
its approval or consent.
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1.14  Calculation of Time

Unless otherwise specified, time periods referred to in this Agreement within or
following which any payment is to be made or act is to be done shall be
calculated by excluding the day on which the period commences and including the
day on which the period ends and by extending the period to the next Business
Day following if the last day of the period is not a Business Day.

1.15  Business Day

Whenever any payment to be made or action to be taken under this Agreement is
required to be made or taken on a day other than a Business Day, such payment
shall be made or action taken on the next Business Day following such day.

1.16  Incorporation of Schedules

The following are the schedules attached to and incorporated in this Agreement.

      Financial Schedules

      Schedule 3.2         -    Allocation of Purchase Price
      Schedule 8.1(d)(iv)  -    Unaudited Financial Statements of NutraMax as
                                of August 31, 1999

      Asset Schedules

      Schedule 1.1(g)      -    Property Lease
      Schedule 1.1(j)      -    Owned Property and Permitted Encumbrances
      Schedule 2.1(c)      -    Contracts and Material Contracts
      Schedule 2.1(d)      -    Intellectual Properties
      Schedule 2.1(e)      -    Inventories, Materials in Processing, Spare
                                Parts and Vehicles
      Schedule 2.1(f)      -    Machinery and Equipment

      Disclosure Schedules

      Schedule 1.1(c)      -    Benefit Plans
      Schedule 1.1(d)      -    Employees
      Schedule 2.1(a)      -    Customer List
      Schedule 5.3         -    Qualification to do Business
      Schedule 5.5         -    Required Consents
      Schedule 5.9         -    Authorizations
      Schedule 5.16        -    Reservations as to Consents
      Schedule 5.22        -    Environmental Matters
      Schedule 5.23        -    Insurance
      Schedule 5.24        -    Litigation
      Schedule 5.25        -    Product Warranties
<PAGE>

                                     -11-

     Schedule of Forms

     Schedule 1.1(a)   -   Form of Agreement of Sale
     Schedule 1.1(e)   -   Form of Distribution Agreement
     Schedule 1.1(h)   -   Form of MIZA Guarantee
     Schedule 1.1(i)   -   Form of NutraMax Guarantee

                                  ARTICLE II
                                    ASSETS

2.1  Assets

Subject to the terms and conditions hereof, the Vendor agrees to sell, assign
and transfer to the Purchaser and the Purchaser agrees to purchase from the
Vendor at the Time of Closing on the Closing Date, effective as of the Effective
Time, the following Assets, namely:

     (a)  Books and Records. All Books and Records relevant exclusively to the
          -----------------
          Assets, the operation of the Assets and Intellectual Properties
          including the customer list attached as Schedule 2.1(a);

     (b)  Buildings and Fixtures. All Buildings and Fixtures described in
          ----------------------
          Schedule 2.1(b);

     (c)  Contracts. Subject to the provisions of Section 2.2 hereof, the full
          ---------
          benefit of all provisions of all Contracts described in Schedule
          2.1(c);

     (d)  Intellectual Properties. Certain rights, title, interest and benefits
          -----------------------
          of the Vendor and NutraMax in and to the Intellectual Properties
          described in Schedules 2.1(d);

     (e)  Inventories.  All Inventories described in Schedule 2.1(e);
          -----------

     (f)  Machinery and Equipment. The Machinery and Equipment described in
          -----------------------
          Schedule 2.1(f);

     (g)  Materials in Processing. All Materials in Processing described in
          -----------------------
          Schedule 2.1(e);

     (h)  Name. The exclusive right of the Purchaser to the name "Optopics" or
          ----
          any variation thereof;

     (i)  [Intentionally Omitted];

     (j)  Real Property.  All the Owned Property and the Leased Property;
          -------------

     (k)  Spare Parts.  All Spare Parts described in Schedule 2.1(e); and
          -----------

     (l)  Vehicles. The trucks, cars and other motor vehicles described in
          --------
          Schedule 2.1(e).
<PAGE>

                                      -12-

2.2  Assignment of Contracts

Nothing in this Agreement shall be construed as an attempt to assign any Assets
described as a Contract or Lease which, as a matter of law, is not assignable in
whole or in part without the Consent of the other party or parties thereto,
unless such Consent shall have been given (and in this Agreement, the benefits
under such non-assigned Contracts and Leases are referred to as the "Contractual
Rights"). In accordance with the provisions of Section 7.4, the Vendor shall use
its best efforts to obtain such Consents, and whether or not such Consents are
obtained, shall take all reasonable actions to preserve the benefit of such
Contracts, Leases and the Contractual Rights for the Purchaser.

2.3  [Intentionally Omitted].

2.4  Grant of Know-How and Other Intellectual Properties

With respect to Know-How and other Intellectual Properties listed in Schedule
2.1(d), (other than the aNDAs) the Vendor hereby grants to the Purchaser or its
nominee the non-exclusive right, with sub-licensing rights, to use the Know-How
and other Intellectual Properties with respect to the manufacture, use and sale
of pharmaceutical product. The Vendor hereby grants to the Purchaser or its
nominee the exclusive right (to the extent the Vendor has such right), with
sublicensing rights, to use the aNDAs set out in Schedule 2.1(d).

                                  ARTICLE III
                                PURCHASE PRICE

3.1  Purchase Price

The aggregate purchase price (the "Purchase Price") payable by the Purchaser to
the Vendor for the Assets shall be Three Million Six Hundred Thousand United
States Dollars (U.S. $3,600,000.00) subject to the following post-Closing
adjustments on account of actual Inventories and Materials in Processing as at
the Closing Date.

If the Vendor's aggregate cost of the Inventories and Materials in Processing as
at the Closing Date is less than One Million Six Hundred Thousand United States
Dollars (U.S. $1,600,000.00), the Purchase Price shall be reduced by the amount
that is equal to the difference of such cost and One Million Six Hundred
Thousand United States Dollars (U.S. $1,600,000.00). For example, if such cost
is One Million Five Hundred Thousand United States Dollars (U.S. $1,500,000.00)
the Purchase Price shall be reduced by One Hundred Thousand United States
Dollars (U.S. $100,000.00).

3.2  Allocation

The Vendor and the Purchaser hereby agree to allocate the Purchase Price in
accordance with the provisions of Schedule 3.2 and to execute and file all Tax
returns and prepare all financial statements, returns and other instruments on
the basis of such allocations.
<PAGE>

                                      -13-

3.3  Payment at Closing

At the Time of Closing, the Purchaser shall pay to the Vendor the amount of the
Purchase Price by wire transfer pursuant to the instructions of the Vendor.

3.4  [Intentionally omitted.]

3.5  Payment of Sales Tax and Registration Charges on Transfer

The Purchaser shall be liable for and shall pay directly all land transfer
taxes, federal and state sales taxes and all other Taxes, registration charges
or other like charges properly payable by a buyer upon and in connection with
the conveyance and transfer of Assets by the Vendor to the Purchaser hereunder.

                                  ARTICLE IV
                              ASSUMED LIABILITIES

4.1  Assumed Liabilities

Subject to Closing, the Purchaser hereby agrees to discharge, perform and
fulfill the following obligations and liabilities with respect to the operation
of the Assets and from the Effective Time (collectively, the "Assumed
Liabilities"):

     (a)  all obligations or liabilities under the Contracts and the Leases
          arising in respect of the period after the Effective Time and not
          related to any default existing prior to or as a consequence of
          Closing;

     (b)  any liability expressly assumed by the Purchaser under Article 12;

     (c)  obligations and liabilities arising under the Closing Agreements to
          which the Purchaser is a party; and

     (d)  any other obligations expressly assumed hereunder.

4.2  Excluded Liabilities

Except for the Assumed Liabilities, the Purchaser shall not assume and shall
have no obligation to discharge, perform or fulfill any other liabilities or
obligations, contingent or otherwise, of the Vendor in respect of the Business
or Assets of any kind whatsoever (collectively, the "Excluded Liabilities")
including:

     (a)  Accounts Payable;

     (b)  liabilities incurred or accruing due in respect of periods prior to
          the Effective Time under the Contracts or Leases;

     (c)  any assessment or reassessment for income, corporate, capital, sales,
          excise or other Taxes, duties or imposts of any kind whatsoever of the
          Vendor or relating to the Business or Assets in respect of a period
          prior to the Effective Time;
<PAGE>

                                      -14-

     (d)  any third party product liability or warranty liability arising at any
          time in respect of products of the Business processed or shipped on or
          prior to the Closing Date, even though a Claim therefor may be made or
          filed after the Effective Time;

     (e)  any liability of the Vendor to the employees of the Business arising
          in respect of a period prior to the Effective Time; and

     (f)  any liability for pre-closing liabilities pursuant to Environmental
          Laws.

4.3  Assumption of Contractual Liabilities

Notwithstanding anything in this Agreement, the Purchaser shall not assume and
shall have no obligation to discharge any liability or obligation under any
Contract or Lease (a) which, as a matter of law, is not assignable in whole or
in part without the Consent of the other party or parties thereto, unless such
Consents have been obtained, and the value of such Contracts, Leases and
Contractual Rights shall have enured to the Purchaser; and (b) which, as a
matter of law, cannot be assumed by the Purchaser without the Consent of the
other party or parties thereto, unless such Consent shall have been given.

                                   ARTICLE V
                 REPRESENTATIONS AND WARRANTIES OF THE VENDOR

The Vendor represents and warrants to the Purchaser, and acknowledges and
confirms that the Purchaser is relying upon such representations and warranties
in connection with the purchase by the Purchaser of the Assets, as follows:

5.1  Due Constitution of the Vendor

The Vendor is a corporation duly incorporated and validly existing and in good
standing under the laws of the State of Delaware.

5.2  Power

The Vendor has all necessary power to own and sell the Assets.

5.3  Qualification to do Business

The Vendor is duly qualified, licensed or registered to carry on business in the
jurisdictions listed in Schedule 5.3. The jurisdictions listed in Schedule 5.3
include all jurisdictions in which the nature of Assets or the Business makes
such qualification necessary or where the Vendor owns or leases any material
properties or assets or conducts any material business, except where failure to
qualify would have no material adverse effect upon the Assets, taken as a whole.

5.4  Validity of Agreement

     (a)  The Vendor has all necessary corporate and other power to enter into
          and perform its obligations under this Agreement and the Closing
          Agreements.
<PAGE>

                                      -15-

     (b)  The execution, delivery and performance by the Vendor of this
          Agreement and the Closing Agreements and the consummation of the
          transactions contemplated thereby:

          (i)   have been duly authorized by all necessary action on the part of
                the Vendor; and

          (ii)  do not (or would not with the giving of notice or the lapse of
                time) result in a material violation or a material breach of, or
                a material default under or give rise to a right of termination,
                amendment or cancellation or the acceleration of any material
                obligation under (A) any constating documents or by-laws of the
                Vendor; (B) any material contracts or material instruments to
                which the Vendor is a party or by which the Vendor is bound; or
                (C) any Laws applicable to the Vendor; which in any such case
                would have a material adverse effect upon the Assets.

     (c)  This Agreement and the Closing Agreements constitute legal, valid and
          binding obligations of the Vendor enforceable against the Vendor in
          accordance with their respective terms.

5.5  Restrictive Documents

The Vendor is not subject to, or a party to, any charter or by-law or other
constating document restriction, Law, Claim, contract or instrument, Encumbrance
or other restriction of any kind or character which would (a) prevent the
consummation of the transactions contemplated by this Agreement or any Closing
Agreement; or (b) compliance by it with the terms, conditions and provisions
hereof or thereof which would restrict the ability of the Purchaser to acquire
the Assets or utilize the Assets in the manufacture of ophthalmic products,
except for the necessity of obtaining the Consents and the Authorizations
described in Schedules 5.5 and 5.9.

5.6  Commercial Relationships

Since August 31, 1999, the commercial relationships between the Vendor and its
vendors and customers have not been materially adversely affected.

5.7  No Material Adverse Change

Since August 31, 1999, there has been no material change in the Assets arising
out of fire, explosion, accident, casualty, labour trouble, flood, drought,
riot, storm, condemnation, act of God, public force or otherwise, which has
materially adversely affected or which could reasonably be expected to
materially adversely affect the Assets; and

the Vendor has not:

     (a)  permitted any of the Assets to become subjected to any Encumbrance
          except for Permitted Encumbrances or Encumbrances to be discharged at
          or prior to Closing;
<PAGE>

                                      -16-

     (b)  sold, transferred or otherwise disposed of any Assets except for (i)
          assets which are minor in nature and not essential to the operation of
          the Business, and (ii) the sale of its inventories in the ordinary
          course of the Business;

     (c)  granted any unscheduled general increase in the rate of wages,
          salaries or bonuses for executives or other employees employed in
          connection with the Business;

     (d)  cancelled or waived any material claims or rights relating to the
          Assets; or

     (e)  cancelled or reduced any of its insurance coverage relating to the
          Assets; and

the Vendor has:

     (f)  maintained adequate levels of Inventories which in the reasonable
          opinion of the Vendor are adequate to operate the Assets;

     (g)  used its best efforts to keep available the services of its employees
          and agents and to maintain its relations and goodwill with the
          suppliers, customers, distributors and any others having business
          relations with the Vendor;

     (h)  used reasonable efforts consistent with past practice to preserve the
          possession and control of Assets and to preserve the confidentiality
          of any confidential or proprietary information of the Business; and

     (i)  continued to make such capital expenditures as are necessary for the
          adequate operation of the Assets and to ensure basic maintenance of
          the Assets.

5.8  Compliance with Laws

The Vendor is conducting the Business in compliance with all applicable health
and safety, product manufacturing and other Laws of every jurisdiction in which
its business is carried on, except for acts of non-compliance which in the
aggregate are not material to the Assets.

5.9  Authorizations

The Vendor owns, holds, possesses or lawfully uses in the operation of the
Assets all Authorizations which are necessary for it to conduct such operation
as presently conducted or for the ownership and use of its Assets. All such
Authorizations are listed and described in Schedule 5.9 and the Vendor has not
received any notice of any Claim of default, nor to the best of the knowledge of
the Vendor is the Vendor in default, or are requirements outstanding, with
respect to any such Authorizations, other than as described in Schedule 5.9.
<PAGE>

                                      -17-

5.10  Title to Assets

The Vendor is the absolute and beneficial owner of the Assets and has good and
marketable title thereto free and clear of all Encumbrances except for Permitted
Encumbrances and Encumbrances to be discharged at or prior to the Closing Date.

5.11  No Options on Assets, Etc.

Except for the Purchaser under this Agreement, no Person has any written or oral
agreement, option, understanding or commitment, or any right or privilege
capable of becoming such for the purchase from the Vendor of any of the Assets,
other than pursuant to purchase orders and similar agreements accepted or
entered into by the Vendor in the ordinary course of its Business.

5.12  Condition of Inventories

All packaging materials purchased as part of the Materials in Processing shall
be in good condition and commercially useable by the Purchaser for the purposes
of manufacture and distribution of ophthalmic products.

5.13  Real Property

      (a) The Vendor is not the owner of, or under any agreement or option to
          own, any real property or any interest therein, used or to be used in
          the Business, other than the Owned Property and the Leased Property.

      (b) To the best of the knowledge of the Vendor, neither the Owned Property
          nor the Leased Property, nor the Buildings and Fixtures thereon, nor
          the use, operation or maintenance thereof for the purpose of carrying
          on the Business, violates any restrictive covenant or any provision of
          any Law, or encroaches on any property owned by any other Person. No
          condemnation or expropriation proceeding is pending or, to the best of
          the knowledge of the Vendor, threatened which would preclude or impair
          the use of any such property or any part thereof for the purposes for
          which it is currently used. As of June 30, 1999, there were no
          material outstanding work orders with respect to any of the Assets
          from or required by any municipality, police department, fire
          department, sanitation, health or safety authorities or from any other
          Person, and there are no material matters under discussion with or by
          the Vendor relating to work orders which have not been disclosed to
          the Purchaser.

5.14  Lease

The Vendor is not a party, or under any agreement or option to become a party,
to any lease with respect to real property used or to be used in the Business,
other than the Lease, and the Vendor is a party to the Lease. Except as set
forth in Schedule 1.1(g), the Lease is in good standing, creates a good and
valid leasehold estate in the Leased Property thereby demised and is in full
force and effect. With respect to the Lease (a) all rents and additional rents
due to the date hereof have been paid; (b) neither the lessor nor, to the best
of the knowledge of the Vendor, the lessee is in default thereunder; (c) no
waiver, indulgence or postponement of the lessee's obligations
<PAGE>

                                      -18-

thereunder has been granted by the lessor; (d) to the best of the knowledge of
the Vendor there exists no event of default or event, occurrence, condition or
act, (subject to the requirement for Consents) which, with the giving of notice
or the lapse of time, would become a default under such Lease; (e) to the best
of the knowledge of the Vendor the Vendor has not violated any of the terms or
conditions under any such Lease in any material respect; and (f) to the best of
the knowledge of the Vendor, all of the covenants to be performed by the lessee
under the Lease have been fully performed. To the best of the knowledge of the
Vendor, the Leased Property is adequate and suitable for the purposes for which
it is presently being used. Schedule 5.14 contains a true, correct and complete
copy of the Lease and any amendment or extension thereof.

5.15  Material Contracts

Except for Contracts with Affiliates of the Vendor, the material Contracts
listed in Schedule 2.1(c) constitute all of the material Contracts of the
Business. Except as set forth in Schedule 1.1(c), the Vendor, with respect to
the Business or the Assets, is not a party to nor bound by any of the following
which would have a material adverse effect on the ownership of the Assets by the
Purchaser following Closing:

     any employment agreement, bonus, deferred compensation, pension, profit
     sharing, stock option, phantom stock plan, employee stock purchase, health,
     insurance, retirement or other employee benefit plan, any collective
     agreements or any agreement (oral or written) providing for compensation
     out of the ordinary course to be paid to any employee as a consequence of
     the sale of any substantial portion of the Assets;

except for the Contracts and the Leases.

5.16  Consents

To the best of the knowledge of the Vendor, no person from whom consent to
assignment and novation of any of the Contracts identified in Schedule 5.16 has
expressed reservations regarding the giving of such consent.

5.17  No Breach of Contracts

Each of the Contracts is in full force and effect, unamended in any material
respect, and there exists no default or event of default or event, occurrence,
condition or act (including the sale of the Assets hereunder) which, with the
giving of notice or the lapse of time would become a default or event of default
thereunder, which would have a material adverse effect on the Assets, except for
the necessity of obtaining the Consents. The Vendor has not violated or
breached, in any material respect, any of the material terms or conditions of
any Contract, and to the best of the knowledge of the Vendor, all the covenants
to be performed by any other party thereto have been fully performed, and the
Vendor has not received notice of termination of any of the Contracts or any
notice alleging material breach thereof.

5.18  Intellectual Property Rights

The Vendor's labeller code and the aNDAs shall each be in full force and effect,
and in compliance with the relevant FDA rules and regulations.
<PAGE>

                                      -19-

5.19  Books and Records

All Books and Records of the Business have been fully and properly kept in
accordance with GAAP and there are no material inaccuracies or discrepancies of
any kind contained or reflected therein. None of the Vendor's records, systems,
controls, data or information are recorded, stored, maintained, operated or
otherwise wholly or partly dependent upon or held by any means (including any
electronic, mechanical or photographic process, whether computerized or not)
which (including all means of access thereto and therefrom) are not under the
exclusive ownership and direct control of the Vendor.

5.20  Taxes

There are no arrears nor any default in respect of the payment of any Taxes
payable in respect of the Assets which if unpaid, would have a material adverse
effect on the Assets and all Taxes and other assessments due and payable in
respect of the Assets have been paid or accrued, and no Claim for additional
Taxes or other assessments has been made in respect of the Business and is
currently outstanding. The Vendor is not in arrears or in default in respect of
the filing of any required federal, state, municipal or other Tax return in
respect of the Business or the Assets which if unfiled would have a material
adverse effect on the Assets.

5.21  Employees

      (a) To the best of the knowledge of the Vendor, with respect to the
          operation of the Assets, the Vendor is in compliance in all material
          respects with all Laws respecting employment and employment practices,
          terms and conditions of employment, pay equity and wages and hours and
          has not and is not engaged in any unfair labour practice.

      (b) No unfair labour practice, complaint or grievance against the Vendor
          is pending or, to the best of the knowledge of the Vendor, threatened
          before any labour relations board or similar Governmental Entity with
          respect to the operation of the Assets.

      (c) There is no labour strike, dispute, slowdown or stoppage actually
          pending or involving or, to the best of the knowledge of the Vendor,
          threatened against the Vendor with respect to the operation of the
          Assets.

      (d) No union representation question currently exists respecting the
          employees of the Vendor in connection with the operation of the
          Assets.

      (e) No grievance which might have a material adverse effect upon the
          Vendor or the operation of the Assets exists, no arbitration
          proceeding arising out of or under any Collective Bargaining Agreement
          is pending, and no Claim therefor has been asserted.

      (f) No Collective Bargaining Agreement is currently being negotiated by
          the Vendor with respect to the employees of the Vendor and there are
          no Collective Bargaining Agreements in force with respect to the
          employees of the Vendor.
<PAGE>

                                      -20-

5.22  Environmental Matters

      (a) The Vendor has not received any Notice of non-compliance, and to the
          best of the knowledge of the Vendor, there are no facts or
          circumstances which could give rise to a Notice of non-compliance with
          any Environmental Laws or Environmental Permits.

      (b) All Environmental Permits are listed in Schedule 5.22 and are valid
          and in full force and effect. To the best of the knowledge of the
          Vendor, there are no proceedings in progress, pending or threatened,
          that may result in the cancellation, revocation, suspension,
          rescission or amendment of any Environmental Permit. To the best of
          the knowledge of the Vendor, there is no pending or threatened order
          by any environmental regulatory authority requiring improvement or
          other work to be conducted on the Owned Property or the Leased
          Property.

      (c) Except as disclosed in Schedule 5.22, with respect to the operation of
          the Assets

          (i)   the Vendor has not been charged with or convicted of an offence
                for non-compliance with any Environmental Laws, and has not been
                fined or otherwise sentenced or settled any prosecution short of
                conviction; and

          (ii)  the Vendor has not received any Notice of judgment or
                commencement of proceedings of any nature, or experienced any
                search and seizure, and to the best of the knowledge of the
                Vendor is not under investigation related to any breach or
                alleged breach of Environmental Laws.

      (d) The Vendor has maintained, in all material respects, documents and
          records concerning the Environment in the manner and for the time
          periods required by Environmental Laws.

      (e) Except as disclosed in Schedule 5.22,

          (i)   to the best of the knowledge of the Vendor, there is no
                currently existing environmental condition or circumstance that
                could materially interrupt the performance of the Business;

          (ii)  the Vendor has not received any request for information with
                respect to the disposal of waste on, at or under any of the
                Owned Properties or Leased Properties, or the existence of a
                waste disposal site on, at or under any of the Owned Properties
                or Leased Properties;

          (iii) no part of the Owned Properties or Leased Properties, while
                owned or leased by the Vendor, or any affiliate of the Vendor,
                has been used by anyone for the disposal of wastes or as a dump
                site, either temporarily or permanently; and
<PAGE>

                                      -21-

          (iv) to the best of the knowledge of the Vendor, all pollution control
               equipment operated as part of the Business is effective in
               meeting applicable emissions limits and effluent pre-treatment
               standards.

     (f)  All representations and warranties of the Vendor contained in this
          Section 5.22 shall be deemed for all purposes of this Agreement to
          have been made to the best of the actual knowledge of the Vendor,
          after due and diligent review of all of the Environmental Reports, and
          reports prepared by any consultants, experts or engineers retained in
          connection with the preparation of the Environmental Reports.

5.23 Insurance

The Vendor maintains insurance policies with responsible insurers as are
appropriate to the Assets in such amounts and against such risks as are
customarily carried and insured against by prudent owners of comparable Assets.
All such policies of insurance coverage are in full force and effect while the
Business and the Assets remain the property of the Vendor. The Vendor is not in
material default with respect to any of the provisions contained in any such
insurance policy and has not failed to give any material notice or present any
claim under any such insurance policy in due and timely fashion. Schedule 5.23
includes a list setting forth any and all (a) material Claims, with reasonable
particulars, made under any such policies of insurance maintained by or for the
benefit of the Vendor over the past two (2) calendar years prior to the date
hereof, and (b) customers and suppliers of the Business, including their names
and addresses, who have been added as named insureds on such insurance policies,
or who hold certificates entitling them to notice of cancellation of such
insurance policies.

5.24 Litigation

Except as set forth in Schedule 5.24, there is no Claim, at law or in equity, by
any Person, nor any arbitration, administrative or other proceeding by or before
(or to the best of the knowledge of the Vendor any investigation by) any
Governmental Entity pending, or, to the best of the knowledge of the Vendor,
threatened against or affecting any of the Assets, and the Vendor does not know
of any valid basis for any such Claim, arbitration or investigation. Except as
set forth in Schedule 5.24, the Vendor is not subject to any judgment, order,
charge or decree entered in any lawsuit or proceeding affecting or respecting
the Assets.

5.25 Warranties

Except as set forth in Schedule 5.25, the Vendor has not given any guarantee or
warranty in respect of any of the products sold or the services provided by the
Business, except warranties made in the ordinary course, and except for
warranties implied by law.

5.26 Year 2000 Compliance

To the best of the knowledge of the Vendor, the Assets are Year 2000 Compliant
and the Vendor is not aware of any Year 2000 Problems materially adversely
affecting the Assets or materially adversely affecting any Third Parties.
<PAGE>

                                      -22-

                                  ARTICLE VI
                REPRESENTATIONS AND WARRANTIES OF THE PURCHASER

The Purchaser represents and warrants to the Vendor, and acknowledges and
confirms that the Vendor is relying on such representations and warranties in
connection with the sale by the Vendor of the Assets, as follows:

6.1  Due Incorporation and Existence of the Purchaser

The Purchaser is a corporation incorporated and existing under the laws of the
State of Delaware.

6.2  Validity of Agreement

     (a)  The Purchaser has all necessary corporate and other power to enter
          into and perform its obligations under this Agreement and the Closing
          Agreements to which it is a party and to perform its obligations
          hereunder and thereunder.

     (b)  The execution, delivery and performance by the Purchaser of this
          Agreement and the Closing Agreements to which it is a party and the
          consummation of the transactions contemplated thereby have been duly
          authorized by all necessary corporate action on the part of the
          Purchaser and do not (or would not with the giving of notice or the
          lapse of time) result in a violation or a breach of, or a default
          under or give rise to a right of termination, amendment or
          cancellation or the acceleration of any obligation under (i) any
          constating documents or by-laws of the Purchaser, (ii) any contracts
          or instruments to which the Purchaser is a party or by which the
          Purchaser is bound; or (iii) any Laws applicable to the Purchaser.

     (c)  This Agreement and the Closing Agreements to which the Purchaser is a
          party constitute legal, valid and binding obligations of the Purchaser
          enforceable against it in accordance with their respective terms.

6.3  Restrictive Documents

     The Purchaser is not subject to, or a party to, any charter or by-law
restriction, any Law, any Claim, any contract or instrument, any Encumbrance or
any other restriction of any kind or character which would prevent the
consummation of the transactions contemplated by this Agreement or any Closing
Agreement or compliance by the Purchaser with the terms, conditions and
provisions hereof or thereof.

                                  ARTICLE VII
                     PRE-CLOSING COVENANTS OF THE PARTIES

7.1  Operation of Assets Prior to Closing

     (a)  During the Interim Period, the Vendor shall operate the Assets in the
          normal and ordinary course thereof, subject to the provisions of
          Subsections 7.1(b) and 7.1(c).
<PAGE>

                                      -23-

     (b)  Without limiting the generality of Subsection 7.1(a), during the
          Interim Period the Vendor shall not, without the prior written consent
          of the Purchaser:

          (i)    permit any of the Assets to be subjected to any Encumbrance
                 except for Permitted Encumbrances or Encumbrances to be
                 discharged at or prior to Closing;

          (ii)   sell, transfer or otherwise dispose of any Assets except for
                 (A) Assets which are minor in nature and not essential to the
                 operation of the Business, and (B) the sale of its Inventories
                 in the ordinary course of the Business;

          (iii)  grant any unscheduled general increase in the rate of wages,
                 salaries, or bonuses for executives or other employees employed
                 in connection with the Business;

          (iv)   cancel or waive any material claims or rights relating to the
                 Assets;

          (v)    make any change in any method of accounting practice applicable
                 to the Business;

          (vi)   cancel or reduce any of its insurance coverage relating to the
                 Assets; or

          (vii)  agree, whether or not in writing, to do any of the foregoing.

     (c)  Without limiting the generality of Subsection 7.1(a), during the
          Interim Period, the Vendor shall:

          (i)    maintain adequate levels of Inventories to carry on the
                 Business as conducted from and after August 31, 1999;

          (ii)   use its best efforts to keep available the services of the
                 present employees and agents of the Business and to maintain
                 its relations and goodwill with the suppliers, customers,
                 distributors and any others having business relations with the
                 Business;

          (iii)  use reasonable efforts consistent with past practice to
                 preserve the possession and control of Assets and to preserve
                 the confidentiality of any confidential or proprietary
                 information of the Business;

          (iv)   use its best efforts to conduct the Business in such a manner
                 that on the Closing Date the representations and warranties of
                 the Vendor contained in this Agreement with respect to the
                 Assets and operation of the Assets shall be true, correct and
                 complete as if such representations and warranties were made on
                 and as of such date;

          (v)    until the Closing Date continue to make such capital
                 expenditures as are necessary or advisable, in the course of
                 business as conducted from and after August 31, 1999, to ensure
                 basic
<PAGE>

                                      -24-

                 maintenance of the Assets and the health and safety of its
                 employees;

          (vi)   immediately upon becoming aware of the existence of:

                 (A)  any Notice from, proceeding before or order of any
                      Governmental Entity requiring it to comply with or take
                      action under any Environmental Law, or

                 (B)  any state of affairs respecting the Leased Properties,
                      Assets or Business which could reasonably be expected to
                      give rise to future Environmental Liabilities and Costs in
                      the amount of $10,000.00 or more, the imposition of any
                      fine, or the shutting down of any facility for any period
                      of time,

                 notify the Purchaser in writing and provide details of any
                 actions taken in response; and

          (vii)  without limiting the generality of the obligations of the
                 Vendor under Paragraph 7.1(c)(vi), notify the Purchaser of any
                 occurrences of the following nature:

                 (A)  receipt of any Notice or Claim to the effect that it is or
                      may be liable to any Person as a result of the Discharge
                      or threatened Discharge of any Substance into the
                      Environment in, on, under or adjacent to its Leased
                      Properties or any other property relating to the Business;

                 (B)  receipt of any Notice that it is subject to investigation
                      by any Governmental Entity concerning whether any Remedial
                      Action is needed to respond to the Discharge or threatened
                      Discharge of any Substance into the Environment in, on,
                      under or adjacent to its Leased Properties or any other
                      property relating to the Business;

                 (C)  receipt of any Notice that all or any portion of its
                      Leased Properties is subject to an order or an Encumbrance
                      under or pursuant to any Environmental Law; or

                 (D)  receipt of any Notice of the commencement of any judicial
                      or administrative proceeding alleging a violation of any
                      Environmental Law with respect to its Leased Properties,
                      or by it with respect to its Leased Properties.

7.2  Actions to Satisfy Closing Conditions

Each of the Parties hereby agrees to take all such actions as are within its
power to control and to use its best efforts to cause other actions to be taken
which are not within its power to control, so as to ensure compliance with all
of the conditions set forth in Article 8.
<PAGE>

                                      -25-

7.3  Transfer of the Assets

Subject to formal registrations, which may be completed as soon as practicable
following Closing, the Vendor shall take all necessary and reasonable steps and
proceedings to permit good title to the Assets sold hereunder to be duly and
validly transferred and assigned to the Purchaser at the Time of Closing, free
of all Encumbrances other than Permitted Encumbrances.

7.4  Request for Consents

The Vendor shall use its best efforts to obtain, prior to Closing, all Consents
which are required under the Contracts. Such Consents must be upon such terms as
are acceptable to the Purchaser, acting reasonably. The Purchaser shall
cooperate in obtaining such Consents.

7.5  Filings and Authorizations

Each of the Vendor and the Purchaser, as promptly as practicable after the
execution hereof, (a) shall make, or cause to be made, all such filings and
submissions under all Laws applicable to it, as may be required for it to
consummate the purchase and sale of the Assets and the other transactions
contemplated herein in accordance with the terms of this Agreement; (b) shall
use all reasonable efforts to obtain, or cause to be obtained, all
authorizations, approvals, consents and waivers from all Persons and
Governmental Entities necessary or advisable to be obtained by it in order to
consummate such transfer and other transactions contemplated herein; and (c)
shall use all reasonable efforts to take, or cause to be taken, all other
actions necessary, proper or advisable in order for it to fulfil its obligations
hereunder. The Vendor and the Purchaser shall coordinate and cooperate with one
another in exchanging such information and supplying such assistance as may be
reasonably requested by each in connection with the foregoing.

7.6  Bulk Sales Laws

The Vendor shall comply with the provisions of relevant bulk sales Laws. The
Vendor will indemnify the Purchaser with respect to all costs, expenses, damages
and losses which the Purchaser may incur or suffer as a result of the Vendor's
non-compliance with such Laws, except to the extent that such costs, expenses,
damages or losses arise from the Purchaser's failure to pay and satisfy all of
the Assumed Liabilities.

7.7  Notice of Untrue Representation or Warranty

Each of the Parties shall promptly notify the other Party upon any
representation or warranty of such Party contained in this Agreement becoming
untrue or incorrect during the Interim Period, and for the purposes of this
Section each representation and warranty shall be deemed to be given at and as
of all times during the Interim Period.

7.8  Exclusive Dealing

During the Interim Period, the Vendor shall not take any action to, directly or
indirectly, encourage, initiate or engage in discussions or negotiations with,
or provide any information to, any Person, other than the Purchaser, concerning
any purchase of the
<PAGE>

                                      -26-

Assets or the Business, or any merger, sale of substantial assets or similar
transaction involving the Business.

                                 ARTICLE VIII
                             CONDITIONS OF CLOSING

8.1  Conditions for the Benefit of the Purchaser

The purchase and sale of the Assets and other transactions contemplated herein
are subject to the following conditions to be fulfilled or performed at or prior
to the Time of Closing, which conditions are for the exclusive benefit of the
Purchaser and may be waived in whole or in part by the Purchaser in its sole
discretion.

     (a)  Truth of Representations and Warranties of the Vendor. The
          -----------------------------------------------------
          representations and warranties of the Vendor contained in this
          Agreement shall be true and correct as of the Closing Date with the
          same force and effect as if such representations and warranties had
          been made on and as of such date, and the Vendor shall have executed
          and delivered a certificate of a senior officer to that effect. The
          receipt of such certificate and the Closing shall not be a waiver of
          the representations and warranties of the Vendor which are contained
          in this Agreement. Upon the delivery of such certificate, the
          representations and warranties of the Vendor in Article 5 shall be
          deemed to have been made on and as of the Closing Date with the same
          force and effect as if made on and as of such date.

     (b)  Performance of Covenants by Vendor. The Vendor shall have fulfilled or
          ----------------------------------
          complied with all covenants herein contained to be performed or caused
          to be performed by it at or prior to the Time of Closing.

     (c)  Consents and Authorizations. Those material Consents and
          ---------------------------
          Authorizations so identified in Schedule 5.9, shall have been
          obtained, on terms acceptable to the Purchaser acting reasonably, in
          order to permit the Closing on the terms and conditions set out in
          this Agreement without adversely affecting, or resulting in the
          violation of a breach of or a default under or any termination,
          cancellation, amendment or acceleration of any obligation under any
          material licence, permit, Lease or Contract in connection with the
          Assets or the Business.

     (d)  Miscellaneous Conditions. The following conditions shall be satisfied:
          ------------------------

          (i)    the Purchaser shall have been permitted reasonable access to
                 the Business including placing one of its employees at the
                 Owned Property from and after the date hereof. Such employee
                 shall act as a consultant to the C.O.O. of the Vendor in
                 matters relating to the Business and the C.O.O. shall take such
                 employee's advice into consideration in making decisions
                 regarding the operation of the Business;

          (ii)   the completion by or on behalf of the Purchaser of an
                 environmental review in scope and process as determined by the
<PAGE>

                                      -27-

                 Purchaser which shall disclose no material environmental
                 liabilities, risks or deficiencies, currently existing,
                 including, but not limited to, compliance with ISRA and
                 previous administrative consent orders ("ACO") issued by the
                 State of New Jersey and various permits for the discharge of
                 water and transportation of wastes, including any ACO issued to
                 Ashford Laboratories, Lilex Partners, the Vendor and/or
                 NutraMax; and

          (iii) the Buildings and Fixtures shall be in a state of maintenance
                and repair consistent with such state as at August 24, 1999;

     (e)  Deliveries. The Vendor shall have delivered or caused to be delivered
          ----------
          to the Purchaser the following in form and substance satisfactory to
          the Purchaser, acting reasonably:

          (i)    certified copies of (A) extracts from the charter documents,
                 by-laws or other constating documents of the Vendor relating to
                 the execution of documents; (B) the resolutions of the board of
                 directors or any duly authorized committee thereof, of the
                 Vendor approving the entering into of this Agreement and the
                 completion of all transactions contemplated hereunder; and (C)
                 all other instruments evidencing necessary action of the Vendor
                 and of authorizations, if any, with respect to such matters;

          (ii)   certificates of the Secretary, Assistant Secretary or other
                 similar official of the Vendor certifying the names and true
                 signatures of its officers authorized to sign this Agreement
                 and the other instruments to be delivered hereunder;

          (iii)  a certificate of status, compliance, good standing or like
                 certificate with respect to the Vendor issued by appropriate
                 government officials of the jurisdiction of its organization or
                 incorporation and of each jurisdiction in which the Vendor
                 carried on the Business as listed in Schedule 5.3;

          (iv)   the certificate referred to in Subsection 8.1(a);

          (v)    [a certificate pursuant to o and all similar legislation in the
                 relevant jurisdictions stating that the relevant workers'
                 compensation board or similar authority has no outstanding
                 claim in respect of the Business or the Assets];

          (vi)   Books and Records relevant exclusively to the Business;

          (vii)  the (A) transfers or assignments of the Authorizations
                 described in Schedule 5.9 and (B) assignments and novations of
                 those Contracts so identified in Schedule 2.1(c); and

          (viii) all necessary deeds, conveyances, bills of sale, assurances,
                 transfers, assignments and any other instruments necessary or
                 reasonably required effectively to transfer the Assets to the
<PAGE>

                                      -28-

                 Purchaser with a good and marketable title, free and clear of
                 all Encumbrances other than Permitted Encumbrances;

     (f)  Proceedings. All proceedings to be taken in connection with the
          -----------
          transactions contemplated by this Agreement shall be reasonably
          satisfactory in form and substance to the Purchaser and the Purchaser
          shall have received copies of all such instruments and other evidence
          as it may reasonably request in order to establish the consummation of
          such transactions and the taking of all proceedings in connection
          therewith.

8.2  Non-Performance by Vendor

If any condition, obligation or covenant of the Vendor to be performed at or
prior to the Time of Closing shall not have been fulfilled or performed in all
material respects by such time, the Purchaser may terminate this Agreement by
notice in writing to the Vendor, and in such event the Purchaser shall be
released from all of its obligations hereunder and all amounts paid theretofore
on account of the Purchase Price shall forthwith be repaid to the Purchaser. The
Vendor shall only be released from its obligations hereunder if the condition or
conditions for the non-performance of which the Purchaser has terminated this
Agreement are not reasonably capable of being performed or caused to be
performed by the Vendor. Notwithstanding the foregoing, the Purchaser shall be
entitled to waive compliance with any of such conditions, obligations or
covenants in whole or in part if it sees fit to do so without prejudice to any
of its rights of termination in the event of non-performance of any other
condition, obligation, or covenant in whole or in part.

8.3  Conditions for the Benefit of the Vendor

The purchase and sale of the Assets and other transactions contemplated herein
are subject to the following conditions to be fulfilled or performed at or prior
to the Time of Closing, which conditions are for the exclusive benefit of the
Vendor and may be waived in whole or in part by the Vendor in its sole
discretion:

     (a)  Truth of Representations and Warranties of the Purchaser. The
          --------------------------------------------------------
          representations and warranties of the Purchaser contained in this
          Agreement shall be true and correct as of the Closing Date with the
          same force and effect as if such representations and warranties had
          been made on and as of such date, and the Purchaser shall have
          executed and delivered a certificate of a senior officer to that
          effect. The receipt of such evidence and the Closing shall not be a
          waiver of the representations and warranties of the Purchaser which
          are contained in this Agreement. Upon the delivery of such
          certificates, the representations and warranties of the Purchaser in
          Article 6 shall be deemed to have been made on and as of the Closing
          Date with the same force and effect as if made on and as of such date.

     (b)  Performance of Covenants by Purchaser. The Purchaser shall have
          -------------------------------------
          fulfilled or complied with all covenants herein contained to be
          performed or caused to be performed by it at or prior to the Time of
          Closing.
<PAGE>

                                      -29-

     (c)  Deliveries. The Purchaser shall have delivered or caused to be
          ----------
          delivered to the Vendor the following in form and substance
          satisfactory to the Vendor, acting reasonably:

          (i)    certified copies of (A) extracts from the charter documents,
                 by-laws or other constating documents of the Purchaser relating
                 to the execution of documents; (B) the resolutions of the board
                 of directors or any duly authorized committee thereof of the
                 Purchaser approving the entering into of this Agreement and the
                 completion of all transactions contemplated hereunder; and (C)
                 all other instruments evidencing necessary action of the
                 Purchaser and of authorizations, if any, with respect to such
                 matters.

          (ii)   certificates of the Secretary, Assistant Secretary or other
                 similar official of the Purchaser certifying the names and true
                 signatures of its officers authorized to sign this Agreement
                 and the other instruments to be delivered hereunder;

          (iii)  a certificate of status, compliance, good standing or like
                 certificate with respect to the Purchaser issued by appropriate
                 government officials of the jurisdiction of its organization or
                 incorporation, and of each jurisdiction in which the Purchaser
                 carries on business;

          (iv)   the certificate referred to in Subsections 8.3(a);

          (v)    assignments and novations of those Contracts so identified in
                 Schedule 2.1(c); and

          (vi)   formal confirmation of the assumption by the Purchaser of all
                 Assumed Liabilities.

     (d)  Proceedings. All proceedings to be taken in connection with the
          -----------
          transactions contemplated by this Agreement shall be reasonably
          satisfactory in form and substance to the Vendor and it shall have
          received copies of all such instruments and other evidence as it may
          reasonably request in order to establish the consummation of such
          transactions and the taking of all proceedings in connection
          therewith.

8.4  Non-Performance by Purchaser

     (a)  If any condition, obligation or covenant of the Purchaser to be
          performed at or prior to the Time of Closing shall not have been
          fulfilled or performed by such time, the Vendor may terminate this
          Agreement by notice in writing to the Purchaser, and in such event the
          Vendor shall be released from all of its obligations hereunder. The
          Purchaser shall only be released from its obligations hereunder if the
          condition or conditions for the non-performance of which the Vendor
          has terminated this Agreement are not reasonably capable of being
          performed or caused to be performed by the Purchaser.
<PAGE>

                                      -30-

     (b)  Notwithstanding the foregoing, the Vendor shall be entitled to waive
          compliance with any of such conditions, obligations or covenants in
          whole or in part if it sees fit to do so without prejudice to any of
          its rights of termination in the event of non-performance of any other
          condition, obligation, or covenant in whole or in part.

8.5  Mutual Conditions Precedent

The purchase and sale of the Assets and other transactions contemplated herein
are subject to the following terms and conditions to be fulfilled at or prior to
the Time of Closing:

     (a)  No Legal Action. No action or proceeding shall be pending or
          ---------------
          threatened by any Person in any jurisdiction, to enjoin, restrict or
          prohibit any of the transactions contemplated hereby or the right of
          the Purchaser to utilize the Assets after Closing on substantially the
          same basis as theretofore operated by the Vendor.

     (b)  Closing Agreements. The Purchaser and the Vendor and/or their
          ------------------
          respective Affiliates shall have entered into each of the Closing
          Agreements.

If any of the conditions precedent set forth in this Section 8.5 shall not have
been fulfilled in all material respects at or prior to the Time of Closing, this
Agreement shall be terminated, and the Parties shall be released from all
obligations hereunder.

                                  ARTICLE IX
                 CLOSING, TRANSFER OF POSSESSION, RISK OF LOSS

9.1  Date, Time and Place of Closing

The completion of the transactions contemplated by this Agreement shall take
place at the offices of Ballard Spahr Andrews & Ingersoll, LLP, 1735 Market
Street, 51st Floor, Philadelphia, Pennsylvania on the Closing Date at the Time
of Closing, or at such other place, on such other date, and at such other time
as may be agreed upon in writing between the Vendor and the Purchaser.

9.2  Closing Procedures

     (a)    The Vendor and the Purchaser shall complete the Closing upon the
            mutual release of all documents on the Closing Date and payment of
            the Purchase Price.

     (b)    Subject to satisfaction or waiver by the relevant Party of the
            conditions of Closing set forth herein, at the Time of Closing the
            Vendor shall deliver actual possession of the Assets, and upon such
            delivery the Purchaser shall pay or satisfy the Purchase Price in
            accordance with Section 3.3. The transfer of possession of Assets
            shall be deemed to take effect as at the Effective Time.
<PAGE>

                                      -31-

9.3      Risk of Loss

From the date hereof up to the Time of Closing, the Assets shall be and remain
at the risk of the Vendor. If, prior to the Time of Closing, all or any part of
the Assets are destroyed or damaged by fire or any other casualty or are
appropriated, expropriated or seized by any Governmental Entity or other lawful
authority, the Purchaser shall have the option, exercisable by notices in
writing given within five (5) Business Days of the Purchaser receiving notice in
writing from the Vendor of such destruction, damage, expropriation or seizure:

      (a)    to complete the purchase without reduction of the Purchase Price,
             in which event all proceeds of insurance or compensation for
             expropriation or seizure shall be payable to the Purchaser, and all
             right and claim of the Vendor to any such amounts not paid by the
             Closing Date shall be assigned to the Purchaser; or

      (b)    of terminating this Agreement and not completing the purchase, in
             which case all obligations of the Purchaser shall terminate
             forthwith upon the Purchaser giving notice as required herein and
             all amounts paid theretofore on account of the Purchase Price shall
             forthwith be repaid to the Purchaser.

                                   ARTICLE X
            SURVIVAL OF REPRESENTATIONS AND WARRANTIES; INDEMNITIES

10.1  Survival of Representations and Warranties

      (a)    The representations and warranties of the Vendor contained in this
             Agreement shall survive the Closing and, notwithstanding such
             Closing and any investigation made by or on behalf of the
             Purchaser, shall continue in full force and effect for the benefit
             of the Purchaser for a period of one (1) year from the Closing
             Date, (except for the representations and warranties set out at
             Section 5.22 which shall continue in full force and effect for a
             period of two (2) years) and any Claim in respect thereof (except a
             Claim based on fraud, which may be made at any time) shall be made
             in writing within such time periods in accordance with the
             provisions of Section 10.4.

      (b)    The representations and warranties of the Purchaser contained in
             this Agreement shall survive the Closing and, notwithstanding such
             Closing and any investigation made by or on behalf of any of the
             Vendor, shall continue in full force and effect for the benefit of
             the Vendor for a period of one (1) year from the Closing Date, and
             any Claim in respect thereof (except a Claim based on fraud, which
             may be made at any time) shall be made in writing within such time
             period in accordance with the provisions of Section 10.4.

10.2  Indemnification in Favour of the Purchaser

      (a)    The Vendor shall indemnify and save each of the Purchaser and its
             directors, officers, employees, agents and representatives (in
             respect of
<PAGE>

                                      -32-

             whom the Purchaser hereby acts as agent and trustee with respect
             thereto) harmless of and from any Claim or Loss suffered by,
             imposed upon or asserted against the Purchaser as a result of, in
             respect of, connected with or arising out of, under or pursuant to:

             (i)    any failure of the Vendor to perform or fulfil any of its
                    covenants in all material respects, under this Agreement;

             (ii)   subject to the limitation period set forth in Subsection
                    10.1(a), any material breach or inaccuracy of any
                    representation or warranty given by the Vendor contained in
                    this Agreement;

             (iii)  any and all liabilities of the Business as at the Effective
                    Time, including the Excluded Liabilities, which are not
                    expressly assumed by the Purchaser;

             (iv)   [Intentionally Omitted];

             (v)    any dealings by or on behalf of the Vendor with any Person
                    other than the Purchaser with respect to the sale of the
                    Assets or the Business; and

             (vi)   the failure of the Parties to comply with any applicable
                    bulk sales Laws in respect of the transaction of purchase
                    and sale contemplated hereunder, provided that the Claim or
                    Loss is not the result of any failure by the Purchaser to
                    pay the Assumed Liabilities.

10.3  Indemnification in Favour of the Vendor

The Purchaser shall indemnify and save the Vendor and its respective directors,
officers, employees, agents and representatives (in respect of whom the Vendor
hereby acts as agent and trustee with respect thereto) harmless of and from any
Claim or Loss suffered by, imposed upon or asserted against the Vendor as a
result of, in respect of, connected with or arising out of, under or pursuant
to:

      (a)    any failure by the Purchaser to perform and fulfil in all material
             respects, any covenant of the Purchaser under this Agreement;

      (b)    subject to the limitation period set forth in Subsection 10.1(b)
             hereof, any material breach or inaccuracy of any representation or
             warranty given by the Purchaser contained in this Agreement; and

      (c)    the assumption and satisfaction or discharge by the Purchaser of
             the Assumed Liabilities.

10.4  Indemnification Proceedings

      (a)    Any Party seeking indemnification under this Article (the
             "indemnified party") shall forthwith notify the Party against whom
             a Claim for indemnification is sought hereunder (the indemnifying
             party") in writing, which notice shall specify, in reasonable
             detail, the nature and estimated
<PAGE>

                                      -33-

             amount of the Claim. If a Claim by a third party is made against an
             indemnified party, and if the indemnified party intends to seek
             indemnity with respect thereto under this Article, the indemnified
             party shall promptly (and in any case within thirty (30) days of
             such claim being made) notify the indemnifying party of such with
             reasonable particulars. The indemnifying party shall have thirty
             (30) days after receipt of such notice to undertake, conduct and
             control, through counsel of its own choosing and at its own
             expense, the settlement or defence thereof, and the indemnified
             party shall cooperate with it in connection therewith; except that
             with respect to settlements entered into by the indemnifying party
             (i) the consent of the indemnified party shall be required if the
             settlement provides for equitable relief against the indemnified
             party, which consent shall not be unreasonably withheld or delayed;
             and (ii) the indemnifying party shall obtain the release of the
             indemnified party. If the indemnifying party undertakes, conducts
             and controls the settlement or defence of such Claim (i) the
             indemnifying party shall permit the indemnified party to
             participate in such settlement or defence through counsel chosen by
             the indemnified party, provided that the fees and expenses of such
             counsel shall be borne by the indemnified party; and (ii) the
             indemnifying party shall promptly reimburse the indemnified party
             for the full amount of any loss resulting from any Claim and all
             related expenses (other than the fees and expenses of counsel as
             aforesaid) incurred by the indemnified party. The indemnified party
             shall not pay or settle any Claim so long as the indemnifying party
             is reasonably contesting any such Claim in good faith and on a
             timely basis. Notwithstanding the two immediately preceding
             sentences, the indemnified party shall have the right to pay or
             settle any such Claim, provided that in such event it shall waive
             any right to indemnity therefor from the indemnifying party.

      (b)    With respect to third party Claims, if the indemnifying party does
             not notify the indemnified party within thirty (30) days after the
             receipt of the indemnified party's notice of a Claim of indemnity
             hereunder that it elects to undertake the defence thereof, the
             indemnified party shall have the right, but not the obligation, to
             contest, settle or compromise the Claim in the exercise of its
             reasonable judgment at the expense of the indemnifying party.

      (c)    In the event of any Claim by a third party against an indemnified
             party, the defence of which is being undertaken and controlled by
             the indemnifying party, the indemnified party shall use all
             reasonable efforts to make available to the indemnifying party
             those employees whose assistance, testimony or presence is
             necessary to assist the indemnifying party in evaluating and in
             defending any such Claims; provided that the indemnifying party
             shall be responsible for the expense associated with any employees
             made available by the indemnified party to the indemnifying party
             hereunder, which expense shall be equal to an amount to be mutually
             agreed upon per person per hour per day for each day or portion
             thereof that such employees are assisting the indemnifying party
             and which expenses shall not exceed the actual cost to the
             indemnified party associated with such employees.
<PAGE>

                                      -34-

      (d)    With respect to third party Claims, the indemnified party shall
             make available to the indemnifying party or its representatives on
             a timely basis all documents, records and other materials in the
             possession of the indemnified party, at the expense of the
             indemnifying party, reasonably required by the indemnifying party
             for its use in defending any Claim and shall otherwise cooperate on
             a timely basis with the indemnifying party in the defence of such
             Claim.

      (e)    With respect to any re-assessment for income, corporate, sales,
             excise, or other Taxes or other liability enforceable by
             Encumbrance against the property of the indemnified party, the
             indemnifying party's right to so contest shall only apply after
             such payment of such re-assessment or the provision of such
             security as is necessary to avoid an Encumbrance being placed on
             the property of the indemnified party.

10.5  Exclusion of Other Remedies

No Party shall have the right to bring any proceeding against any other Party
for a breach of any representation, warranty, covenant, or agreement contained
in this Agreement, except for a proceeding brought in accordance with the
provisions of this Article. This provision is not intended to preclude any
proceeding based on a cause of action or right, including any statutory right,
other than a cause of action in contract or tort for breach of a representation,
warranty, or agreement contained in this Agreement.

                                  ARTICLE XI
                            POST-CLOSING COVENANTS

11.1  Additional Matters

The Vendor and Purchaser covenant and agree that as soon as practicable
following Closing:

      (a)    they shall effect the completion of formal assignments and
             novations of the Contracts;

      (b)    they shall effect the transfer of Authorizations as contemplated by
             Schedule 8.1(c);

      (c)    the Vendor shall effect land titles registrations of the transfer
             contemplated in the Agreement for Sale.

11.2  Further Assurances

From time to time subsequent to the Closing Date, each Party shall at the
request of any other Party execute and deliver such additional conveyances,
transfers and other assurances as may be reasonably required effectually to
carry out the provisions of this Agreement and to transfer the Assets to the
Purchaser.

                                  ARTICLE XII
                            [INTENTIONALLY OMITTED]
<PAGE>

                                      -35-

                                 ARTICLE XIII
                                   EMPLOYEES

13.1  Terms of Employment

The Benefit Plans applicable to the Employees as at the date hereof are as set
forth in Schedules 1.1(c). The Vendor does not maintain a Pension Plan.

13.2  Termination of Employees

The Employees shall be terminated by the Vendor effective as of the Closing
Date.

13.3  Offer of Employment

Effective as of the Closing Date, the Purchaser shall offer employment to the
Transferred Employees on terms and conditions of employment (including salary,
incentives, benefits, pension and severance) on terms to be negotiated with such
Transferred Employees. Offers of employment shall be conditional on Closing and
accepted by the Transferred Employees on or before Closing.

13.4  Indemnification by Vendor

The Vendor shall indemnify and save the Purchaser harmless from and against all
claims, losses, costs, expenses, damages and actions for or to which the
Purchaser may become liable or subject arising in respect of the employment of
the Employees by the Vendor prior to the Effective Time.

                                  ARTICLE XIV
                      NON-COMPETITION AND CONFIDENTIALITY

14.1  Non-Competition and Confidentiality

The Vendor undertakes with the Purchaser that, except with the consent in
writing of the Purchaser it shall not, and it shall use its best endeavours to
procure that no member of the Vendor's Group or any Affiliate of the Vendor's
Group, shall:

      (a)    subject to the provisions of Section 14.2, for the period of five
             (5) years after the Closing Date, anywhere in North America, either
             on their own account or in conjunction with or on behalf of any
             other person, carry on or be engaged, concerned or interested,
             directly or indirectly, whether as shareholder, partner, agent or
             otherwise in carrying on the Restricted Business;

      (b)    for the period of five (5) years after the Closing Date, either on
             their own account or in conjunction with or on behalf of any other
             person, solicit or entice away or attempt to solicit or entice away
             from the Purchaser the customer of any Person who shall at any time
             within the year preceding the date hereof have been a customer or
             identified prospective customer of the Vendor with respect to the
             Restricted Business;

      (c)    for the period of two (2) years after the Closing Date, either on
             their own account or in conjunction with or on behalf of any other
             person enter into
<PAGE>

                                      -36-

             discussions with, invite applications from or make any offers of
             employment to or otherwise retain the services of the employees of,
             or consultants to, the Vendor or the Purchaser; and

      (d)    at any time hereafter make use of or disclose or divulge to any
             person (other than to officers or employees of the Vendor's Group
             whose province it is to know the same) any confidential information
             (other than any information available to the public or disclosed or
             divulged pursuant to an order of a court of competent jurisdiction)
             relating to the identity of the customers of the Business and
             suppliers, its products, finance, contractual arrangements,
             business or methods of business and the Vendor shall use reasonable
             endeavours to prevent the publication or disclosure of any such
             confidential information.

14.2  Limitations

Notwithstanding the provisions of Section 14.1, nothing herein shall prevent the
Vendor from carrying on the business of blow/fill/seal pharmaceutical
manufacturing including blow/fill/seal manufacturing of ophthalmic products.

14.3  Non-Use of Trade Marks

The Vendor and Affiliates of the Vendor shall cease all use of the word
"Optopics" or the Optopics emblem or any words or symbols representing same as
from the Closing Date in relation to the Assets and the Business and at all
times thereafter including (without limitation) all such use on company
notepaper, stationery, vehicles or promotional material and in connection with
any services provided or products manufactured or distributed by them. The
Vendor shall change its corporate name as soon as practicable after Closing to
remove any reference to "Optopics".

14.4  Modification

While the restrictions contained in this clause are considered by the Parties to
be reasonable in all the circumstances, it is recognized that restrictions of
the nature in question may fail for technical reasons and accordingly it is
hereby agreed and declared that if any of such restrictions shall be adjudged to
be void as going beyond what is reasonable in all the circumstances for the
protection of the interests of the Purchaser but would be valid if part of the
wording thereof were deleted or the periods thereof reduced or the range of
activities or area dealt with thereby reduced in scope the said restriction
shall apply with such modifications as may be necessary to make it valid and
effective.

                                  ARTICLE XV
                            RESOLUTION OF DISPUTES

15.1  Resolution of Disputes

      (a)    Any Party shall be entitled to give notice of a dispute in writing
             to any other Party, on any issue which may arise out of or in
             connection with this Agreement or the application, interpretation,
             implementation, validity,
<PAGE>

                                      -37-

             breach or termination of this Agreement, any provisions thereof or
             any agreement concluded in pursuance of this Agreement.

      (b)    The Parties shall attempt in good faith to resolve promptly by
             negotiation any such dispute.

      (c)    If the dispute has not been resolved by negotiation within forty-
             five (45) days of the disputing Party's notice, the Parties shall
             as soon as possible thereafter appoint a mutually acceptable
             independent mediator to assist the Parties in endeavouring to
             settle the dispute.

      (d)    If the dispute has not been resolved by non-binding means as
             provided for above within sixty-five (65) days of the notice of
             dispute, either Party may initiate litigation upon a further thirty
             (30) days written notice to the other Party.

      (e)    Without prejudice to the above procedures, a Party may commence
             legal proceedings and/or seek interlocutory or other conservatory
             relief whether for the purpose of protecting that Party's rights
             under applicable limitation or prescription rules or otherwise.
             Despite such action the Parties shall continue to participate in
             good faith in the procedures specified above.

      (f)    Unless impossible or otherwise impracticable, each Party is
             required to continue to perform its obligations under this
             Agreement pending final resolution of any dispute arising out of or
             relating to this Agreement.

                                  ARTICLE XVI
                                 MISCELLANEOUS

16.1  Notices

Any notice, direction or other instrument required or permitted to be given
hereunder or under any Ancillary Agreement must be in writing and given by
delivering or sending it by certified mail, postage prepaid, return receipt
requested, or by receipted courier service, addressed:

      (a)    to the Purchaser at:

             MIZA Pharmaceuticals USA, Inc.
             c/o MIZA Pharmaceuticals, Inc.
             Suite 1801 Exchange Tower
             10250 - 101 Street
             Edmonton, Alberta
             T5J 3P4

             Attention:   President and CEO

             with a copy to:

             Bennett Jones
             Barristers and Solicitors
             1000, 10035 - 105 Street
<PAGE>
                                      -38-

             Edmonton, Alberta
             T5J 3T2

             Attention:   E. J. Barichello

      (b)    to the Vendor at:

             Optopics Laboratories Corporation
             c/o NutraMax Products, Inc.
             51 Blackburn Drive
             Gloucester, MA
             01930, USA

             Attention:   President

             with a copy to:

             1700 Cary Road
             Huntingdon Valley, PA 19006 5002

             Attention:   Mr. Eugene M. Schloss, Jr.

Any such notice, direction or other instrument given as aforesaid shall be
deemed to have been effectively given, on the fifth Business Day following
mailing or, if by receipted courier service, on the date of delivery. Any Party
may change its address for services from time to time by notice given in
accordance with the foregoing and any subsequent notice shall be sent to the
Party at its changed address.

16.2  Publicity

Save as required by Law or by any stock exchange on which securities of either
of the Parties are listed for trading, neither of the Parties shall issue any
press release or make any other public statement or announcement relating to or
connected with or arising out of this Agreement or any Ancillary Agreement or
the matters contained herein or therein, without obtaining the prior written
approval of the other Parties to the contents and the manner of presentation and
publication thereof, such approval not to be unreasonably withheld or delayed.
If disclosure is required by Law or by any stock exchange, the disclosing Party
shall consult in advance with the other Party and attempt in good faith to
reflect such other Party's concerns in the required disclosure.

16.3  Time of the Essence

Time shall be of the essence of this Agreement.

16.4  Brokers

The Purchaser has entered into an agreement with BKR International Merger &
Acquisitions Group, L.L.C., pursuant to which compensation will be payable to it
upon completion of the purchase of the Assets. The Purchaser assumes sole
responsibility for such payment.
<PAGE>

                                      -39-

The Vendor has entered into an agreement with Prospection International Inc.,
pursuant to which compensation will be payable to it upon completion of the sale
of the Assets. The Vendor assumes sole responsibility for such payment.

Each Party shall indemnify and save harmless the other Party from and against
any Claims whatsoever for any commission or other remuneration payable or
alleged to be payable to any broker, agent or other intermediary who purports to
act or have acted for such Party.

16.5  Third Party Beneficiaries

Except as set forth in Sections 10.2, 10.3 and 10.4, each Party hereto intends
that this Agreement shall not benefit or create any right or cause of action in
or on behalf of any Person other than the Parties hereto, and no Person other
than the Parties hereto, shall be entitled to rely on the provisions hereof in
any action, suit, proceeding, hearing or other forum.

16.6  Expenses

Except as otherwise expressly provided herein, all costs and expenses (including
the fees and disbursements of legal counsel, investment advisers and auditors)
incurred in connection with this Agreement and the transactions contemplated
hereby shall be paid by the Party incurring such expenses.

16.7  Enurement

This Agreement shall enure to the benefit of and be binding upon the Parties,
their successors and any Person becoming a party to this Agreement through the
procedure set out in Section 16.8. This Agreement shall enure to the benefit of
any permitted assigns.

16.8  Assignment

Except as provided in this Section 16.8, none of the rights or obligations
hereunder shall be assignable or transferable by any Party without the prior
written consent of the other Party. The Purchaser shall be entitled, upon giving
notice to the Vendor at any time on or prior to the Closing Date, to assign the
benefits of this Agreement to any Affiliate of the Purchaser subject to the
following two conditions: (a) the Purchaser's assignee shall become jointly and
severally liable with the Purchaser, as a principal and not as a surety, with
respect to all of the representations, warranties, covenants, indemnities and
agreements of the Purchaser; and (b) such assignees shall each execute an
agreement confirming such assignment and the assumption by the assignee of all
obligations of the Purchaser under this Agreement.

16.9  Counterparts

This Agreement may be executed and delivered in any number of counterparts, each
of which when executed and delivered shall be deemed an original but all of
which taken together constitute one and the same instrument. This Agreement may
be delivered by fax.
<PAGE>

                                      -40-

16.10 Non-Merger

Except as otherwise expressly provided in this Agreement, the covenants,
representations and warranties of the Parties contained in this Agreement shall
not merge on and shall survive the Closing and, notwithstanding such Closing, or
any investigation made by or on behalf of any Party, shall continue in full
force and effect. The Closing shall not prejudice any right of one Party against
any other Party in respect of anything done or omitted hereunder or under any of
the Ancillary Agreements or in respect of any right to damages or other
remedies.

IN WITNESS WHEREOF this Agreement has been executed by the Parties as of the
date first above written.

                                         MIZA PHARMACEUTICALS USA, INC.

                                         Per: /s/ Dr. Jack Kachkar
                                             --------------------------
                                         Name:  Dr. Jack Kachkar
                                         Title: President

                                         OPTOPICS LABORATORIES
                                         CORPORATION

                                         Per: /s/ Bernard J. Korman
                                             --------------------------
                                         Name:  Bernard J. Korman
                                         Title: Chairman<PAGE>

                        [LETTERHEAD OF BENNETT JONES]

November 26, 1999

Via Facsimile

Mr. Eugene M. Schloss, Jr.
Attorney at Law
1700 Cary Road
Huntingdon Valley, PA 19006 5002

Dear Gene:

Re:   Optopics Laboratories Corporation

Further to our clients' discussions of November 17, 1999 and our discussions of
November 22, 1999, we believe that NutraMax/Optopics and Miza can address the
following outstanding issues cooperatively so as to be in a position to close
the Optopics transaction in an expedient manner and in accordance with the terms
and conditions of the October 15, 1999 Purchase and Sale Agreement (the
"Agreement"). Please note that even though the items set out in paragraphs 2 to
5 below do not all have specific timelines, Miza believes that such items will
be completed on or before December 10, 1999. The items set out in paragraph 1
are, of course, the items which were specifically discussed by the parties and
are of utmost importance to Miza.

1.    The following outstanding regulatory compliance issues in respect of the
      Optopics facility are required to be dealt with by Optopics to Miza's
      reasonable satisfaction prior to closing:

      (a)    The Vitek Jr CC4/DT Computer Upgrade is scheduled as follows:
             - reports are being written: 11/24/99
             - final validation completion date: 11/30/99.

      (b)    The GC (Gas Chromatography) and UV-Vis (Diode Array
             Spectrophotometer)
             - we understand Hewlett Packard is scheduled to complete the
             validation on 12/09/99
             - we understand the equipment will be in compliance when they
             arrive to do the work and will be in compliance when they leave on
             that day.

      (c)    Requalification of the five micro incubators:
             - we understand all protocols have been written
             - we understand validations will be conducted by Mike Morrelli by
             12/03/99.
<PAGE>

November 26, 1999
Page Two

      (d)    Media Fill for fill room 1
             - we understand media fill is being run today: 11/24/99.

2.    Installation and testing of the USP Water System:
      - we understand installation of system completed: 11/23/99
      - we understand testing completed: 12/02/99
      - we understand final test results completed: 12/07/99.

3.    The following transition matters need to be completed:

      (a)    Notification of Customers:
             - we understand NutraMax has already communicated with its
             customer base related to the sale of assets, and NutraMax
             would be willing to provide (if feasible) mailing labels to
             Miza if they choose to perform a mailing to the customers.

      (b)    Labels, prints, graphic material
             - we understand the above information is being loaded on a zip
             drive so it can be provided to Miza on the date of closing.

      (c)    The Finished Goods inventory at Gloucester should be
             identified so that Miza can complete its inspection at least a
             day before closing; we understand that our respective clients
             are currently coordinating the process for taking inventory
             and will continue to do so up to closing;

      (d)    Data download:

             The download of all applicable data bases and applications
             necessary to run the Optopics business, including documentation on
             customizations that NutraMax has done to systems including
             Optopics' customer history/data from Symix (or Syteline depending
             on the application that NutraMax is utilizing at closing) to Miza's
             database. The parties have agreed to utilize "Decision Resources"
             (Miza's Symix/Syteline consulting group) to mediate this transfer;
             we understand that Decision Resources will be able to separate the
             Optopics data from the NutraMax data subject to appropriate
             confidentiality obligations in favour of NutraMax;

             - we understand download of all applicable data bases and
             applications will be conducted on the day of closing provided Miza
             has a server in place to receive the data and files. The
             transmission will be done electronically and can be executed upon
             request.

      (e)    Documentation of the current Optopics' customer order processing
             system as handled by NutraMax is required; we understand that this
             work has begun.

4. The following human resources issues need to be finalized:

<PAGE>

November 26, 1999
Page Three

      (a)    All Optopics employees will be terminated effective on closing
             and all required payments shall be made to them by Optopics on
             closing;

      (b)    The distribution of funds for the 401(k) and section 125 plan will
             be made according to the terms of the respective plans and
             applicable law and regulations;

      (c)    All benefits including, but not limited to, medical insurance,
             dental insurance and group life insurance will terminate at
             midnight on the date of termination as per company policy and the
             terms of the respective Plans. Eligible employees will have the
             option COBRA as per applicable law and regulations.

      We understand Dr. Kachkar's consultant, Burt Bartzhoff, is finalizing all
      such matters with Optopics' Carol Woloss in the Human Resources
      Department.

5.    Leased space:

      Optopics is leasing warehouse space in Bridgeton, New Jersey for obsolete
      raw material inventory. As Miza is not purchasing this inventory Optopics
      needs to assign someone to handle its removal from the Bridgeton location.

      - we understand NutraMax intends to remove the product from the leased
      space prior to closing.

We would like to highlight that NutraMax/Optopics have been very helpful and
supportive during this entire process in the interest of an orderly closing of
the transaction. The recent PLMA show in Chicago demonstrated to us that the
NutraMax/Optopics customers and vendors are aware of and supportive of the
transaction. This is of course good news and underscores Miza's commitment to
helping you preserve the business in anticipation of closing.

Miza advises that, to the best of its knowledge, it will be in a position, on or
before closing, to satisfy or comply with the Miscellaneous Provisions imposed
by its banker attached hereto as Exhibit "A".

Subject to the provisions of the Agreement, Miza considers that the foregoing
items constitute an exhaustive list of the issues respecting the contemplated
transaction. It appears therefore that Optopics and Miza will be in a position
to close immediately upon completion of all of the above items. The parties
accordingly agree to amend the Agreement to extend the Closing Date to December
10, 1999. In anticipation of such closing the parties shall hold a pre-closing
on December 9, 1999 at the offices of Ballard Spahr Andrews & Ingersoll, LLP
where all tabled documents shall be held in escrow
<PAGE>

November 26, 1999
Page Four

pending the closing on December 10, 1999. If you agree with the foregoing please
execute a copy of the enclosed letter and return to us by fax today with a hard
copy to follow. I provide this letter to you on behalf of my client.

Yours truly,

BENNETT JONES

Enzo J. Barichello

EJB/ark
cc:      Mr. David Radeke (via facsimile: 978-282-3794)
         Dr. Jack Kachkar

------------------------------------------------------------------------------

Acknowledged and Agreed to by Optopics Laboratories Corporation this 26/th/ day
of November, 1999.
                                             OPTOPICS LABORATORIES
                                             CORPORATION

                                             Per: /s/ David J. Radeke
                                                 ---------------------------
                                             Name:  David J. Radeke
                                             Title: Executive Vice President and
                                                    Chief Operating Officer

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