Document:

First Amendment to Employment Agreement, dated November 22, 2010

 Exhibit 10.41 
 FIRST AMENDMENT 
 TO 

EXECUTIVE EMPLOYMENT AGREEMENT 
 This First Amendment to Executive Employment Agreement (“Agreement”) is made and entered into by Quintiles Transnational Corp., a North Carolina corporation (hereinafter the “Company”)
and Kevin Gordon (hereinafter the “Executive”). This first amendment shall be effective as of July 30, 2010 (the “Effective Date”). 
 WHEREAS, Company and Executive entered into an Executive Employment Agreement effective as of July 30, 2010, pursuant to which Company hired Executive as its Executive Vice President, Chief Financial
Officer; and 
 WHEREAS, Company and Executive desire to amend the Agreement as set forth below, in order to clarify the parties’ original
intention with respect to Section 10.2, “Change of Control”. 
 NOW, THEREFORE, in consideration of the mutual covenants and
agreements of the parties herein contained and other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties agree as follows: 

 

	 	1.	Change of Control. Section 10.2 of the Agreement is deleted in its entirety and replaced with the following revised Section 10.2:

 “10.2 Upon a Change of Control, all Options shall become vested and exercisable. In the event of
any conflict between the terms and conditions of this Agreement and the terms and conditions of any option agreement between Company and Executive, the terms and conditions of this Agreement shall control.” 

 

	 	2.	There are no further changes to the terms of the Agreement. Except as would be inconsistent with the terms of this first amendment to the Agreement, all other terms and
conditions of the Agreement not otherwise defined in this first amendment shall have the meaning ascribed to them in the Agreement. 

 IN WITNESS WHEREOF, the parties have executed this first amendment as of the date indicated below. 
  

									
	QUINTILES TRANSNATIONAL CORP	 		  	KEVIN GORDON
				
	by:	  	 /s/ Beverly L. Rubin
	 		  	 /s/ Kevin K. Gordon

					
	Name:	  	 Beverly L. Rubin
	 		  	Date:	  	 11/22/10

					
	Title:	  	 Asst. Secretary
	 		  		  	
					
	Date:	  	 11/22/10Executive Employment Agreement, dated June 14, 2004

 Exhibit 10.42 
 [Quintiles Transnational Logo] 
 EXECUTIVE EMPLOYMENT AGREEMENT 

This Executive Employment Agreement (“Agreement”), dated as of JUNE 14, 2004, is made and entered into by QUINTILES
TRANSNATIONAL CORP., a North Carolina corporation (hereinafter the “Company”) and JOHN D. RATLIFF (hereinafter the “Executive”). The Company desires to employ Executive as its Chief Financial Officer, and provide adequate
assurances to Executive and Executive desires to accept such employment on the terms set forth below, which terms Executive agreed to in Executive’s offer letter, which is incorporated herein by reference. 

In consideration of the mutual promises set forth below and other good and valuable new consideration, the receipt and sufficiency of
which the parties acknowledge, the Company and Executive agree as follows: 
 1. EMPLOYMENT. The Company employs Executive and
Executive accepts employment on the terms and conditions set forth in this Agreement 
 2. NATURE OF EMPLOYMENT. Executive shall
serve as Chief Financial Officer, which currently reports to the Chairman, and have such responsibilities and authority as the Company may assign from time to time. Additionally, Executive agrees to perform such other duties consonant with those of
an executive at his level as the Company may set from time to time. Executive shall also serve, without additional compensation, in such other officer and director positions of any affiliates of the Company to which he may be appointed. 

2.1 Executive shall perform all duties and exercise all authority in accordance with, and shall otherwise comply with, all Company
policies, procedures, practices and directions. 
 2.2 Executive shall devote all working time, best efforts, knowledge and
experience to perform successfully his duties and advance the Company’s and/or its Affiliates’ interests. During his employment, Executive shall not engage in any other business activities of any nature whatsoever (including board
memberships) for which he receives compensation without the Company’s prior written consent; provided, however, this provision does not prohibit him from personally owning and trading in stocks, bonds, securities, real estate, commodities or
other investment properties for his own benefit, which do not create actual or potential conflicts of interest with the Company and/or its Affiliates. As used in this Agreement, “Affiliates” shall mean: (i) any Company’s parent,
subsidiary or related entity; and/or (ii) any entity directly or indirectly controlled or beneficially owned in whole or part by the Company or Company’s parent, subsidiary or related entity. 

2.3 Executive’s base of operation shall be Research Triangle Park, North Carolina, subject to business travel as may be necessary in
the performance of Executive’s duties. 

  
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 3. COMPENSATION. 
 3.1 BASE SALARY. Executive’s monthly salary for all services rendered shall be $33,333.33 (less applicable withholdings), payable in accordance with the Company’s policies, procedures and
practices as they may exist from time to time. Executive’s salary shall be reviewed in accordance with the Company’s policies, procedures and practices as they may exist from time to time. 

3.2 ANNUAL CASH BONUS PLAN. Executive may participate on a basis commensurate with his position as a senior executive officer, as
determined by the Company, in the Company’s annual cash bonus plan which may be made available from time to time to Company executives; provided, however, that Executive’s participation is subject to the applicable terms, conditions and
eligibility requirements of the plan documents, some of which are within the plan administrator’s discretion, as they may exist from time to time. 
 3.3 TAX RETURNS. Executive shall be entitled to tax return preparation and reasonable financial planning, consultation and advice by the Company’s accounting firm and/or legal counsel and/or
financial consultants as the Company may provide from time to time to Company executives at Executive’s level. 
 3.4 OTHER
BENEFITS. Executive may participate in all medical, dental and disability insurance, 401(k), pension, personal leave, car allowance and other employee benefit plans and programs, except Executive may not receive severance payments other than
specified in this Agreement; provided, however, that Executive’s participation in benefit plans and programs is subject to the applicable terms, conditions and eligibility requirements of these plans and programs, some of which are within the
plan administrator’s discretion, as they may exist from time to time. 
 3.5 BUSINESS EXPENSES. Executive shall be
reimbursed for reasonable and necessary expenses actually incurred by him in performing services under this Agreement in accordance with and subject to the terms and conditions of the applicable Company reimbursement policies, procedures and
practices as they may exist from time to time. Expenses covered by this provision include but are not limited to travel, entertainment, professional dues, subscriptions and dues, fees and expenses associated with membership in various professional,
and business and civic associations of which Executive’s participation is in the Company’s best interest. 
 3.6
Nothing in this Agreement shall require the Company to create, continue or refrain from amending, modifying, revising or revoking any of the plans, programs or benefits set forth in Sections 3.2 through 3.5. Any amendments, modifications, revisions
and revocations of these plans, programs and benefits shall apply to Executive. 

  
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 3.7 If, at any time during which Executive is receiving salary or post-termination payments
from the Company, he receives payments on account of mental or physical disability from any Company-provided plan, then the Company, at its discretion, may reduce his salary or post-termination payments by the amount of such disability payments.

 4. TERM OF EMPLOYMENT. The original term of employment shall be for a one (1) year period commencing on July 1,
2004 and terminating on June 30, 2005 subject to the following provisions: 
 4.1 Upon the expiration of the original or
any renewal term of employment, Executive’s employment shall be automatically renewed for an additional one (1) year period unless, at least ninety (90) days prior to the renewal date, either party gives the other party written notice
of its intent not to continue the employment relationship. During any renewal term of employment, the terms, conditions and provisions set forth in this Agreement shall remain in effect unless modified in accordance with Section 15. 

4.2 Either party may terminate the employment relationship without cause at any time upon giving the other party sixty (60) days
written notice. 
 4.3 The Company may terminate the Executive’s employment relationship immediately without notice at any
time for the following reasons which shall constitute “Cause”: (i) Executive’s death; (ii) Executive’s physical or mental inability to perform the essential functions of his duties satisfactorily for a period of 180
consecutive days or 180 days in total within a 365-day period as determined by the Company in its reasonable discretion and in accordance with applicable law; (iii) any act or omission of Executive constituting willful misconduct (including
willful violation of the Company’s policies), gross negligence, fraud, misappropriation, embezzlement, criminal behavior, conflict of interest or competitive business activities which, as determined by the Company in its reasonable discretion,
shall cause material harm, or any other actions that are materially detrimental to the Company or any Affiliates’ interest; (iv) any other reason recognized as “cause” under applicable law; or (v) Executive’s material
breach of this Agreement. 
 4.4 Executive may terminate Executive’s employment with the Company as a result of the
Company’s failure to cure its material breach of this Agreement after Executive has given the Company notice of the material breach and at least thirty (30) days to cure the breach (or such longer period as may be reasonably required to
cure the breach as long as the Company is making good faith efforts to do so). 
 4.5 This Agreement shall terminate upon the
termination of the employment relationship with the following exceptions: Section 6 (Trade Secrets, Confidential Information, Company 

  
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Property and Competitive Business Activities), 7 (Intellectual Property Ownership), 8 (License), 9 (Release), and 12 (Change in Control) shall survive the termination of Executive’s
employment and/or the expiration or termination of this Agreement, regardless of the reasons for such expiration or termination. 
 5. COMPENSATION AND BENEFITS UPON TERMINATION. 
 5.1 The Company’s obligation
to compensate Executive ceases on the effective termination date except as to: (i) amounts due at that time; (ii) any amount subsequently due pursuant to the plan described in Section 3.2; and (iii) any compensation and/or
benefits to which he may be entitled to receive pursuant to Sections 5.2, 5.3, 5.4 or 5.5. 
 5.2 If the Company terminates
Executive’s employment pursuant to Sections 4.1 (notice of non-renewal) or 4.2 (without cause), or if Executive terminates Executive’s employment pursuant to Section 4.4 (breach of Agreement), then the Company’s sole obligation
to Executive in lieu of any other damages or other relief to which he otherwise may be entitled, shall be to pay Executive: (i) amounts due on the effective date of the termination; (ii) any amounts subsequently due pursuant to the plan
described in Section 3.2; and (iii) subject to Executive’s compliance with Sections 6,7,8 and 9 and subject to Sections 3.7 and 5.6 (release), 24 monthly payments where each payment equals executive’s monthly rate of base salary
in effect at the time of such termination multiplied by 1.55, less applicable withholdings. 
 5.3 During the period during
which Executive receives post-termination payments pursuant to Section 5.2 (but in no event after the date the Executive becomes eligible for comparable coverage) he may continue to participate, to the extent permitted by the applicable plans
and subject to their terms, conditions and eligibility requirements, in all employee welfare benefits plans (as defined by the Employee Retirement Income Security Act of 1974, as amended) in which Executive participated on his effective termination
date. The Company will pay or, at the Company’s discretion, reimburse Executive for the premiums actually paid, to continue coverage under such plans during the period. Notwithstanding the Company’s payment of or reimbursement for the
premiums, any coverage under such plans shall be subject to the terms, conditions and eligibility requirements of such plans, and nothing in this Section shall constitute any guaranty of coverage. 

5.4 If the Company terminates Executive’s employment as provided in Sections 4.3 (i) (death), (ii) (physical or mental
inability to perform), (iii) (materially harmful acts or omissions), (iv) (other reasons recognized as “cause”) or (v) (Executive’s material breach) or if the Executive terminates his employment pursuant to
Section 4.1 (notice of non-renewal) or Section 4.2 (without cause), then the Company’s sole obligation shall be to pay Executive: (i) amounts due on the effective termination date and (ii) any amounts subsequently due
pursuant to the plan described in Section 3.2. Executive, except 

  
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when employment terminates pursuant to Section 4.3(i) (death), shall comply with Sections 6,7,8 and 9 of this Agreement upon expiration or termination of this Agreement. 

5.5 The Company’s obligation to provide the payments under Sections 5.2 is conditioned upon Executive’s execution of an
enforceable release of all claims and his compliance with Sections 6, 7, 8 and 9 of this Agreement, in a format similar to that attached hereto. If Executive chooses not to execute such a release or fails to comply with these sections, then the
Company’s obligation to compensate him ceases on the effective termination date except as to amounts due at that time and any amount subsequently due pursuant to the plan described in Section 3.2. 

5.6 Executive is not entitled to receive any compensation or benefits upon his termination except as: (i) set forth in this
Agreement; (ii) otherwise required by law; or (iii) otherwise required by any employee benefit plan in which he participates. Nothing in this Agreement, however, is intended to waive or supplant any death, disability, retirement, 401(k) or
pension benefits to which he may be entitled under employee benefit plans in which he participates. 
 6. TRADE SECRETS,
CONFIDENTIAL INFORMATION, COMPANY PROPERTY AND COMPETITIVE BUSINESS ACTIVITIES. Executive acknowledges that: (i) the Company and its Affiliates have worldwide business operations, a worldwide customer base, and are engaged in the business of
contract research, sales and marketing, healthcare policy consulting and health information management services to the worldwide pharmaceutical, biotechnology, medical device and healthcare industries; (ii) by virtue of his employment by and
upper-level position with the Company, he has or will have access to Trade Secrets and Confidential Information (as defined in Sections 6.1(5) and 6.1(6)) of the Company and its Affiliates, including valuable information about their worldwide
business operations and entities with whom they do business in various locations throughout the world, and has developed or will develop relationships with their customers and others with whom they do business in various locations throughout the
world; and (iii) the Trade Secret, Confidential Information and Competitive Business Activities’ provisions set forth in this Agreement are reasonably necessary to protect the Company’s and its Affiliates’ legitimate business
interests, are reasonable as to the time, territory and scope of activities which are restricted, do not interfere with public policy or public interest and are described with sufficient accuracy and definiteness to enable him to understand the
scope of the restrictions imposed on him/her. 
 6.1 TRADE SECRETS AND CONFIDENTIAL INFORMATION. Executive acknowledges that:
(i) the Company and/or its Affiliates will disclose to him certain Trade Secrets and Confidential Information; (ii) Trade Secrets and Confidential Information are the sole and exclusive property of the Company and/or its Affiliates (or a
third party providing such information to the Company and/or its Affiliates) and the Company and/or its Affiliates or such third party owns all worldwide rights therein under patent, copyright, trademarks, trade secret, confidential information or
other property right; and (iii) the disclosure of Trade Secrets and Confidential Information to Executive does not confer upon him any license, interest or rights of any kind in or to the Trade Secrets or Confidential Information. 

  
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 6.1(1) Executive may use the Trade Secrets and Confidential Information only while he is
employed or otherwise retained by the Company and only then in accordance with applicable Company policies and procedures and solely for the Company’s benefit. Except as authorized in the performance of services for the Company, Executive will
hold in confidence and will not, either directly or indirectly, in any form, by any means, or for any purpose, disclose, reproduce, distribute, transmit, reverse engineer, decompile, disassemble, or transfer Trade Secrets or Confidential Information
or any portion thereof. Upon the Company’s request, Executive shall return Trade Secrets and Confidential Information and all related materials. 
 6.1(2) If Executive is required to disclose Trade Secrets or Confidential Information pursuant to a court order, subpoena or other government process or such disclosure is necessary to comply with
applicable law or defend against claims, he shall: (i) notify the Company promptly before any such disclosure is made; (ii) at the Company’s request and expense take all reasonably necessary steps to defend against such disclosure,
including defending against the enforcement of the court order, other government process or claims; and (iii) permit the Company to participate with counsel of its choice in any proceeding relating to any such court order, subpoena, other
government process or claims. 
 6.1(3) Executive’s obligations with regard to Trade Secrets shall remain in effect for as
long as such information shall remain a trade secret under applicable law. 
 6.1(4) Executive’s obligations with regard
to Confidential Information shall remain in effect while he is employed or otherwise retained by the Company and/or its Affiliates and for fifteen (15) years thereafter. 
 6.1(5) As used in this Agreement, “Trade Secrets” means information of the Company, its Affiliates and its and/or their licensors, suppliers, customers, or prospective licensors or customers,
including, but not limited to, data, formulas, patterns, compilations, programs, devices, methods, techniques, processes, financial data, financial plans, product plans, or lists of actual or potential customers or suppliers, which: (i) derives
independent actual or potential commercial value, from not being generally known to or readily ascertainable through independent development or reverse engineering by persons or entities who can obtain economic value from its disclosure or use; and
(ii) is the subject of efforts that are reasonable under the circumstances to maintain its secrecy. 
 6.1(6) As used in
this Agreement, “Confidential Information” means information other than Trade Secrets, that is of value to its owner and is treated as confidential, including, but not limited to, future business plans, licensing strategies, advertising
campaigns, information regarding executives and employees, and the terms and conditions of this Agreement; provided, however, Confidential Information shall not include information which is in the public domain or becomes public knowledge through no
fault of Executive. 

  
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 6.2 COMPANY PROPERTY. Upon termination of his employment, Executive shall: (i) deliver
to the Company all records, memoranda, data, documents and other property of any description which refer or relate in any way to Trade Secrets or Confidential Information, including all copies thereof, which are in his possession, custody or
control; (ii) deliver to the Company all Company and/or Affiliates property (including, but not limited to, keys, credit cards, client files, contracts, proposals, work in process, manuals, forms, computer stored work in process and other
computer data, research materials, other items of business information concerning any Company and/or Affiliates client, or Company and/or Affiliates business or business methods, including all copies thereof) which is in his possession, custody or
control; (iii) bring all such records, files and other materials up to date before returning them; and (iv) fully cooperate with the Company in winding up his work and transferring that work to other individuals designated by the Company.

 6.3 COMPETITIVE BUSINESS ACTIVITIES. During his employment and the two (2) years following his effective termination
date (regardless of the reason for the termination), Executive will not engage in the following activities: 
 (A) on
Executive’s own or another’s behalf, whether as an officer, director, stockholder, partner, associate, owner, employee, consultant or otherwise, directly or indirectly: 

(i) compete with the Company or its Affiliates within the geographical areas set forth in Section 6.3(1); except that Executive,
without violating this provision, may become employed by any company which is engaged in the integrated development, discovery, manufacture, marketing and sale of pharmaceutical drugs that does not engage in contract sales and/or research;

 (ii) within the geographical areas set forth in Section 6.3(1), solicit or do business which is the same, similar to or
otherwise in competition with the business engaged in by the Company or its Affiliates, from or with persons or entities: (A) who are customers of the Company or its Affiliates; (B) who Executive or someone for whom he was responsible
solicited, negotiated, contracted or serviced on the Company’s or its Affiliates’ behalf; or (C) who were customers of the Company or its Affiliates at any time during the last year of Executive’s employment with the Company;

 (iii) offer employment to or otherwise solicit for employment any employee or other person who had been employed by the
Company or its Affiliates during the last year of Executive’s employment with the Company; or 
 (B) directly or
indirectly take any action which is materially detrimental or otherwise intended to be adverse to the Company’s and/or Affiliates’ goodwill, name, business relations, prospects and operations. 

  
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 6.3(1) The restrictions set forth in Section 6.3 apply to the following geographical
areas; (i) within a 60-mile radius of the Company and/or its Affiliates where the Executive had an office during the Executive’s employment with the Company and/or its Affiliates; (ii) any city, metropolitan area, county (or similar
political subdivision in foreign countries) in which Executive’s substantial services were provided, or for which Executive had substantial responsibility, or in which Executive performed substantial work on Company and/or Affiliates’
projects, while employed by the Company; and (iii) any city, metropolitan area, county (or similar political subdivisions in foreign countries) in which the Company or its Affiliates is located or does or, during Executive’s employment
with Company, did business. 
 6.3(2) Notwithstanding the foregoing, Executive’s ownership, directly or indirectly, of not
more than one percent of the issued and outstanding stock of a corporation the shares of which are regularly traded on a national securities exchange or in the over-the-counter market shall not violate Section 6.3. 

6.4 REMEDIES. Executive acknowledges that his failure to abide by the Trade Secrets, Confidential Information, Company Property or
Competitive Business Activities provisions of this Agreement would cause irreparable harm to the Company and/or its Affiliates for which legal remedies would be inadequate. Therefore, in addition to any legal or other relief to which the Company
and/or its Affiliates may be entitled by virtue of Executive’s failure to abide by these provisions: (i) the Company will be released of its obligations under this Agreement to make any post-termination payments, including but not limited
to those otherwise available pursuant to Sections 5.2, 5.3, 5.4, 5.5; (ii) the Company may seek legal and equitable relief, including but not limited to preliminary and permanent injunctive relief, for Executive’s actual or threatened
failure to abide by these provisions; (iii) Executive will return all post-termination payments received pursuant to this Agreement, including but not limited to those received pursuant to Sections 5.2, 5.3, 5.4, 5.5; (iv) Executive will
indemnify the Company and/or its Affiliates for all expenses including attorneys’ fees in seeking to enforce these provisions; and (v) if, as a result of Executive’s failure to abide by the Trade Secrets, Confidential Information,
Company Property or Competitive Business Activities provisions, any commission or fee becomes payable to Executive or to any person, corporation or other entity with which Executive has become employed or otherwise associated, Executive shall pay
the Company or cause the person, corporation or other entity with whom he has become employed or otherwise associated to pay the Company an amount equal to such commission or fee. In the event that the Company exercises its right to discontinue
payments under this provision and/or Executive returns all post-termination payments received pursuant to this Agreement, Executive shall remain obligated to abide by the Trade Secrets, Confidential Information, Company Property and Competitive
Business Activities provisions set forth in this Agreement. 
 6.5 TOLLING. The period during which Executive must refrain from
the activities set forth in Sections 6.1 and 6.3 shall be tolled during any period in which he fails to abide by these provisions. 

  
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 6.6 OTHER AGREEMENTS. Nothing in this Agreement shall terminate, revoke or diminish
Executive’s obligations or the Company’s and/or its Affiliates’ rights and remedies under law or any agreements relating to trade secrets, confidential information, non-competition or intellectual property which Executive has executed
in the past or may execute in the future or contemporaneously with this Agreement. 
 7. INTELLECTUAL PROPERTY OWNERSHIP.

 7.1 As used in this Agreement, “Work Product” shall mean the data, materials, documentation, computer programs,
inventions (whether or not patentable), improvements, modifications, discoveries, methods, developments, picture, audio, video, artistic works and all works of authorship, including all worldwide rights therein under patent, copyright, trademark,
trade secret, confidential information or other property right, created or developed in whole or in part by Executive, while employed by the Company (whether developed during work hours or not), whether prior or subsequent to the date of this
Agreement. 
 7.2 All Work Product shall be considered work made for hire by Executive and owned by the Company. If any of the
Work Product may not, by operation of law be considered work made for hire by Executive for the Company, or if ownership of all right, title, and interest of the intellectual property rights therein shall not otherwise vest exclusively in the
Company, Executive hereby assigns to the Company, and upon the future creation thereof automatically assigns to the Company, without further consideration, the ownership of all Work Product. The Company shall have the right to obtain and hold in its
own name copyrights, registrations and any other protection available in the Work Product. Executive agrees to perform, during or after his employment, such further acts which the Company requests as may be necessary or desirable to transfer,
perfect and defend its ownership of the Work Product. 
 7.3 Notwithstanding the foregoing, this Agreement shall not require
assignment of any invention that: (i) Executive developed entirely on his own time without using the Company’s equipment, supplies, facilities, Trade Secrets or Confidential Information; and (ii) does not relate to the Company’s
business or actual or anticipated research or development or result from any work performed by Executive for the Company. 
 7.4
Executive shall promptly disclose to the Company in writing all Work Product conceived, developed or made by him/her, individually or jointly. 
 8. LICENSE. To the extent that any preexisting materials are contained in Work Product which Executive delivers to the Company or its customers, Executive grants to the Company an irrevocable,
nonexclusive, worldwide, royalty-free license to: (i) use and distribute (internally or 

  
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externally) copies of, and prepare derivative works based upon, such preexisting materials and derivative works thereof; and (ii) authorize others to do any of the foregoing. 

9. RELEASE. Executive acknowledges that: (i) as a part of his services, he may provide his image, likeness, voice or other
characteristics; and (ii) the Company may use his image, likeness, voice or other characteristics, to promote the Company, and expressly releases the Company, its Affiliates and its and/or their agents, employees, licensees and assigns from and
against any and all claims which he has or may have for invasion of privacy, right of privacy, defamation, copyright infringement or any other causes of action arising out of the use, adaptation, reproduction, distribution, broadcast or exhibition
of such characteristics. 
 10. EMPLOYEE REPRESENTATION. Executive represents and warrants that his employment and obligations
under this Agreement will not (i) breach any duty or obligation he owes to another or (ii) violate any law, recognized ethics standard or recognized business custom. 
 11. OFFICERS AND DIRECTORS INDEMNIFICATION PROVISIONS. To the extent Executive serves as a Company and/or Affiliate officer or director, Executive shall be entitled to insurance under Company’s
directors and officers’ indemnification policies comparable to any such insurance covering executives of the applicable entity serving in similar capacities. Further, the Company’s bylaws shall contain provisions granting to Executive the
maximum indemnity protection allowed under applicable law and the Company hereby agrees to indemnify and hold harmless Executive in accordance with such maximum indemnity protection allowed under applicable law. 

12. TAX WITHHOLDING. The Company shall have the right to deduct and withhold such amounts from any payment made hereunder as may be
necessary to enable the Company to satisfy any applicable withholding obligation imposed by law. 
 13. NOTICES. All notices,
requests, demands and other communications required or permitted to be given in writing pursuant to this Agreement shall be deemed given and received: (A) upon delivery if delivered personally; (B) on the fifth (5th) day after being
deposited with the U.S. Postal Service if mailed by first class mail, postage prepaid, registered or certified with return receipt requested, at the addresses set forth below; (C) on the next day after being deposited with a reliable overnight
delivery service; or (D) upon receipt of an answer back confirmation, if transmitted by telefax, addressed to the below indicated telefax number. Notice given in another manner shall be effective only if and when received by the addressee. For
purposes of notice, the addresses and telefax number (if any) of the parties shall be as follows: 
  

					
		 	If to the Executive, to:	  	John D. Ratliff
		 		  	4741 Sharpstone Lane
		 		  	Raleigh, NC 27615

  
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		 	If to the Company, to:	  	Quintiles Transnational Corp.
		 		  	4709 Creekstone Drive
		 		  	Riverbirch Building, Suite 300
		 		  	Durham, North Carolina 27703-8411
		 		  	Attn: General Counsel

 provided that: (A) each party shall have the right to change its address for notice, and the person who is to
receive notice, by the giving of fifteen (15) days’ prior written notice to the other party in the manner set forth above; and (B) notices shall be effective if given to the other party in the manner set forth above regardless of
whether a copy was received by the additional addressee specified above. 
 14. WAIVER OF BREACH. The Company’s or
Executive’s waiver of any breach of a provision of this Agreement shall not waive any subsequent breach by the other party. 
 15. ENTIRE AGREEMENT. Except as expressly provided in this Agreement, this Agreement: (i) supersedes all other understandings and agreements, oral or written, between the parties with respect to the
subject matter of this Agreement; and (ii) constitutes the sole agreement between the parties with respect to this subject matter. Each party acknowledges that: (i) no representations, inducements, promises or agreements, oral or written,
have been made by any party or by anyone acting on behalf of any party, which are not embodied in this Agreement; and (ii) no agreement, statement or promise not contained in this Agreement shall be valid. No change or modification of this
Agreement shall be valid or binding upon the parties unless such change or modification is in writing and is signed by the parties. 
 16. SEVERABILITY. If a court of competent jurisdiction holds that any provision or sub-part thereof contained in this Agreement is invalid, illegal or unenforceable, that invalidity, illegality or
unenforceability shall not affect any other provision in this Agreement. Additionally, if any of the provisions, clauses or phrases in the Trade Secrets, Confidential Information or Competitive Business Activities provisions set forth in this
Agreement are held unenforceable by a court of competent jurisdiction, then the parties desire that they be “blue-penciled’ or rewritten by the court to the extent necessary to render them enforceable. 

17. PARTIES BOUND. The terms, provisions, covenants and agreements contained in this Agreement shall apply to, be binding upon and inure
to the benefit of the Company’s successors and assigns. The Company, at its discretion, may assign this Agreement to Affiliates. Because this Agreement is personal to Executive, Executive may not assign this Agreement. 

  
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 18. GOVERNING LAW. This Agreement and the employment relationship created by it shall be
governed by North Carolina law without giving effect to North Carolina choice of law provisions. The parties hereby consent to jurisdiction in North Carolina for the purpose of any litigation relating to this Agreement and agree that any litigation
by or involving them relating to this Agreement shall be conducted in the courts of Wake County, North Carolina or the federal courts of the United States for the Eastern District of North Carolina. 

IN WITNESS WHEREOF, the parties have entered into this Agreement on the day and year first written above. 

 

					
		 	 /s/ J. D. Ratliff

		 	EXECUTIVE
		
		 	QUINTILES TRANSNATIONAL CORP.
			
		 	By:	  	 /s/ Michael Mortimer

			
		 	Title:	  	 EVP, Global Human Resources

  
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