Document:

Form of Amended and Restated Employment Agreement

 Exhibit 10.2 
 [ Date] 
 [Name of Executive Officer] 
 [Address]

 Re:         Amended and Restated Employment Agreement 
 Dear [Name of Executive Officer]: 
 You and Renovis, Inc.
(the “Company”) are parties to an employment agreement dated                         , as amended and restated
on                         , (“Employment Agreement”), which sets forth, among other things, the terms of your
employment with the Company and certain severance benefits payable to you in the event of a qualifying termination of your employment. This letter (the “Agreement”) amends and restates the Employment Agreement to provide you with
additional benefits in the event of certain terminations of your employment in connection with a Change in Control (as defined below). This Agreement supersedes the Employment Agreement and any other agreement or policy to which the Company is a
party with respect to your employment with the Company. Notwithstanding the foregoing, your Proprietary Information and Inventions Agreement remains in full effect. 
 1. DUTIES. Your employment commenced effective as of
                        . As
the                        , you will continue to perform the duties customarily associated with these positions. You will
continue to report to                          and will perform your services on a full-time basis at the Company’s
headquarters located in South San Francisco. Of course, the Company may change your position, reporting structure, duties and work location from time to time as it deems necessary. 
 2. BASE SALARY. You currently receive an annual base salary of
                         for all hours worked paid on a twice-per-month basis, less payroll deductions and withholdings. You
shall be eligible for an increase in your base salary subject to the review and approval of the Compensation Committee of the Board of Directors (the “Compensation Committee”) during your next annual focal performance review and each year
thereafter. 
 3. BONUS. You continue to be eligible to receive an annual bonus targeted at 35% of your base salary based upon your
attainment of performance objectives as recommended by the CEO and determined by the Compensation Committee. You shall be eligible for an increase in your annual bonus opportunity subject to the review and approval of the Compensation Committee
during your next annual focal performance review and each year thereafter. The Company may at any time change or eliminate its bonus program, with prospective effect. 
 4. STOCK OPTIONS AND OTHER AWARDS. Subject to the terms set forth in the Company’s various equity incentive and stock plans, you
have been granted the stock options and deferred stock units listed in the table attached hereto as Exhibit A, with those options marked as cancelled having been cancelled pursuant to that certain stock option cancellation agreement effective
January 4, 2007 between you and the Company. You will continue to be eligible for grants of additional stock options and other equity-based awards, including, without limitation, deferred stock units, subject to the review and approval of the
Compensation Committee during the focal performance review to be undertaken annually. 
  

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 5. BENEFITS. You will continue to be eligible to participate in any of the employee benefit plans
or programs the Company generally makes available to similarly situated employees, pursuant to the terms and conditions of such plans. 
 6.
EXPENSES. You shall be entitled to reimbursement for all ordinary and reasonable out-of-pocket business expenses which are reasonably incurred by you in furtherance of the Company’s business and in accordance with the
Company’s standard policies. 
 7. COMPANY POLICIES AND CONFIDENTIALITY
AGREEMENT. As an employee of the Company, you are expected to abide by all of the Company’s policies and procedures. As a condition of your continued employment and as a condition to any of the Company’s obligations
under this Agreement, you agree to execute, if applicable, and abide by the terms of the Proprietary Information and Inventions Agreement with the Company. 
 8. OTHER AGREEMENTS. By accepting this Agreement, you represent and warrant that your performance of your duties for the Company has not and will not violate any agreements, obligations or understandings
that you may have with any third party or prior employer. You agree not to make any unauthorized disclosure or use, on behalf of the Company, of any confidential information belonging to any of your former employers. You also represent that you are
not in unauthorized possession of any materials containing a third party’s confidential and proprietary information. Of course, during your employment with the Company, you may make use of information generally known and used by persons with
training and experience comparable to your own, and information which is common knowledge in the industry or is otherwise legally available in the public domain. 
 9. OUTSIDE ACTIVITIES. While employed by the Company, you will not engage in any business activity in competition with the Company nor make preparations to do so using working time or resources of the
Company. 
 10. AT-WILL EMPLOYMENT. As an employee of the Company, you may terminate your employment at
any time and for any reason whatsoever simply by notifying the Company. Similarly, the Company may terminate your employment at any time and for any reason whatsoever, with or without cause or advance notice. Your at-will employment relationship
with the Company cannot be changed except in a written agreement signed by the CEO. 
 11. SEVERANCE BENEFITS.

 (a) Termination By The Company Without Cause. If your employment by the Company is terminated by the Company without Cause (as
defined below), or if there is a Constructive Termination (as defined below), in each case at any time prior to the occurrence of a Change in Control (as defined below) or in each case more than thirteen (13) months following the occurrence of
a Change in Control (as defined below), and if you provide the Company with a signed general release of all claims against the Company, in a form provided by and reasonably acceptable to the Company (a “Release”), and do not revoke the
Release within the applicable 

  

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revocation period, if any, the Company shall provide you with the following severance benefits: (1) an amount equal to twelve (12) months of your
base salary at the rate in effect immediately prior to your termination of employment, less applicable withholdings, payable in installments pursuant to the Company’s normal and customary payroll procedures, subject to Section 17 below;
(2) provided that you elect to receive health benefits (e.g., medical and dental) pursuant to the Consolidated Omnibus Budget Reconciliation Act of 1985, as amended (“COBRA”), then for the period beginning on your date of termination
and ending on the date which is twelve (12) full months following your date of termination (or, if earlier, the date on which you begin benefit coverage with another employer), the Company shall pay the costs associated with continuation
coverage pursuant to COBRA; and (3) on your date of termination, you shall immediately become vested with respect to those options to purchase the Company’s capital stock and other equity-based awards that you then hold that would have
vested during the Acceleration Period following your date of termination and/or any restrictions with respect to restricted shares of the Company’s capital stock and other equity-based awards that you then hold that would have vested during the
Acceleration Period following your date of termination shall immediately lapse, and you shall be entitled to exercise any such vested options and other equity-based awards until the expiration date of such options and other equity-based awards set
forth in the stock option or award agreement(s) pursuant to which they were granted. For the purposes of this Section 11(a), “Acceleration Period” shall mean twelve (12) months. 
 You understand and agree that you shall not be entitled to any other severance pay, severance benefits, or any other compensation or benefits other than as set forth in
this paragraph in the event of such a termination, other than as required under applicable law. 
 (b) Termination By The Company With
Cause Or Termination By You. If your employment by the Company is terminated by the Company with Cause (as defined below), or if you voluntarily terminate your employment with the Company (other than pursuant to a Constructive Termination (as
defined below)), you shall not be entitled to any severance pay, severance benefits, or any compensation or benefits from the Company whatsoever, other than as required under applicable law. 
 (c) Termination Following Change in Control. If your employment by the Company is terminated by the Company without Cause (as defined below), or
if there is a Constructive Termination (as defined below), in each case at any time within thirteen (13) months following the occurrence of a Change in Control (as defined below), and if you provide the Company with a signed Release and do not
revoke the Release within the applicable revocation period, if any, the Company shall provide you with the following severance benefits: (1) a lump sum payment equal to the sum of (A) twelve (12) months of your base salary plus
(B) your target annual bonus opportunity, in each case, at the rate in effect immediately prior to the Change in Control, less applicable withholdings, to be paid by the Company within five (5) business days of your Release becoming no
longer subject to revocation by you; (2) provided that you elect to receive health benefits (e.g., medical and dental) pursuant to COBRA, then for the period beginning on your date of termination and ending on the date which is twelve
(12) full months following your date of termination (or, if earlier, the date on which you begin benefit coverage with another employer), the Company shall pay the costs associated with continuation coverage pursuant to COBRA; (3) on your
date of termination, you shall immediately become 

  

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100% vested with respect to all unvested options to purchase the Company’s capital stock and other equity-based awards that you then hold and/or any
restrictions with respect to all restricted shares of the Company’s capital stock and other equity-based awards that you then hold shall immediately lapse, and you shall be entitled to exercise any such vested options and other equity-based
awards until the expiration date of such options and other equity-based awards set forth in the stock option or award agreement(s) pursuant to which they were granted; and (4) for the period beginning on your date of termination and ending on
the date which is twelve (12) full months following your date of termination (or, if earlier, the date on which you accept employment with another employer), the Company shall pay for and provide you with outplacement services through a firm
selected by the Company in its sole discretion in an aggregate amount not to exceed $20,000; provided, however, that if you are terminated by the Company following the effective date of a Change in Control described in clause (d)(2)(b)
below but accept employment with the Company’s successor or acquirer within thirty (30) days after the effective date of the Change in Control on terms and conditions not less favorable to you than those contained in this Agreement, you
shall not be entitled to any severance benefits under this clause (c); provided, further, however, that if your employment is thereafter terminated by the successor or acquiror without Cause (as defined below), or if there is a
Constructive Termination (as defined below), in each case at any time within thirteen (13) months following the occurrence of the Change in Control (as defined below), you shall be entitled to the severance benefits described above in this
clause (c). 
 You understand and agree that you shall not be entitled to any other severance pay, severance benefits, or any other compensation or benefits
other than as set forth in this paragraph in the event of such a termination, other than as required under applicable law. 
 (d)
Definitions. 
 (1) Cause. For purposes of this Agreement, the term “Cause” means: (i) theft, dishonesty or
falsification of any employment or Company records; (ii) malicious or reckless disclosure of the Company’s confidential or proprietary information; (iii) commission of any immoral or illegal act or any gross or willful misconduct,
where the Company reasonably determines that such act or misconduct has (A) seriously undermined the ability of the Company’s management to entrust you with important matters or otherwise work effectively with you, (B) contributed to
the Company’s loss of significant revenues or business opportunities, or (C) significantly and detrimentally affected the business or reputation of the Company or any of its subsidiaries; and/or (iv) your breach of this Agreement or
the failure or refusal by you to work diligently to perform tasks or achieve goals reasonably requested by the Company’s Board of Directors (the “Board”), provided such breach, failure or refusal continues after the receipt of
reasonable notice in writing of such failure or refusal and an opportunity to correct the problem. “Cause” shall not mean a physical or mental disability. 
 (2) Change in Control. For purposes of this Agreement, the term “Change in Control” means the consummation of any of the following transactions: 
 a. the closing of a business combination (such as a merger or consolidation) of the Company with any other corporation or other type of business
entity (such 

  

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as a limited liability company), other than a business combination which would result in the voting securities of the Company outstanding immediately prior
thereto continuing to represent (either by remaining outstanding or by being converted into voting securities of the surviving entity) more than fifty percent (50%) of the total voting power represented by the voting securities of the Company
or such controlling surviving entity outstanding immediately after such business combination; or 
 b. the sale, lease, exchange or
other transfer or disposition by the Company of all or substantially all (more than seventy percent (70%)) of the Company’s assets by value; or 
 c. an acquisition of any voting securities of the Company by any “person” (as the term “person” is used for purposes of Section 13(d) or Section 14(d) of the Securities Exchange
Act of 1934, as amended (the “1934 Act”)) immediately after which such person has “beneficial ownership” (within the meaning of Rule 13d-3 promulgated under the 1934 Act) of more than fifty percent (50%) of the combined
voting power of the Company’s then outstanding voting securities. 
 (3) Constructive Termination. For purposes of this
Agreement, the term “Constructive Termination” means your resignation within sixty (60) days of one or more of the following events which remains uncured thirty (30) days after your delivery of written notice thereof: 

a. the delegation to you of duties or the reduction of your duties, either of which substantially reduces the nature, responsibility, or
character of your position immediately prior to such delegation or reduction; 
 b. a material reduction by the Company in your base
salary in effect immediately prior to such reduction; 
 c. a material reduction by the Company in the kind or level of employee
benefits or fringe benefits to which you were entitled prior to such reduction; or the taking of any action by the Company that would adversely affect your participation in any plan, program or policy generally applicable to employees of equivalent
seniority; and 
 d. the Company’s requiring you to relocate your office to a place more than forty (40) miles from the
Company’s present headquarters location (except that required travel on the Company’s business to an extent substantially consistent with your present business travel obligations shall not be considered a relocation). 
 12. SUCCESSORS. The Company will require any successor (whether direct or indirect, by purchase, merger, consolidation or otherwise) to all or
substantially all (more than seventy percent (70%)) of the business and/or assets of the Company or any of its subsidiaries to expressly assume and agree to perform this Agreement in the same manner and to the same extent that the Company or
any subsidiary would be required to perform it if no such succession had taken place. Failure of the Company to obtain such assumption and agreement prior to the 

  

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effectiveness of any such succession shall be a breach of this Agreement and shall entitle you to the compensation described in Section 11(c) of this
Agreement to which you would be entitled hereunder following a Constructive Termination, as defined in Section 11(d)(3) above, of your employment following a Change in Control, as defined in Section 11(d)(2) above, except that for purposes
of implementing the foregoing, the date on which any such succession becomes effective shall be deemed the date of termination. As used in this Agreement, the “Company” shall mean the Company as defined and any successor to its business
and/or assets as aforesaid which assumes and agrees to perform this Agreement by operation of law or otherwise. 
 13. PARACHUTE
PAYMENTS. 
 (a) Generally. Except as otherwise provided in this Section 13, all amounts payable to you under this
Agreement will be made without regard to whether the deductibility of such payments (considered together with any other entitlements or payments otherwise paid or due to you) would be limited or precluded by Section 280G of the Internal Revenue Code
of 1986, as amended (the “Code”) and without regard to whether such payments would subject you to the excise tax levied on certain “excess parachute payments” under Section 4999 of the Code (the “Parachute Excise Tax”).

 (b) Gross-Up. If all or any portion of the payments or other benefits provided under this Agreement, either alone or together with
any other payments and benefits which you receive or are entitled to receive (whether paid or payable or distributed or distributable) pursuant to the terms of this Agreement or otherwise pursuant to or by reason of any other agreement, policy,
plan, program or arrangement, including without limitation any stock option, deferred stock unit, stock appreciation right or similar right, or the lapse or termination of any restriction on or the vesting or exercisability of any of the foregoing
(collectively, the “Payment”) would result in the imposition of a Parachute Excise Tax, then, subject to the Gross-Up Reduction (as defined below), you will be entitled to an additional payment (the “Gross-Up Payment”) in an
amount such that the net amount of the Payment and the Gross-Up Payment retained by you after the calculation and deduction of all excise taxes (including any interest or penalties imposed with respect to such taxes) on the payment and all federal,
state and local income tax, employment tax and excise tax (including any interest or penalties imposed with respect to such taxes) on the Gross-Up Payment provided for in this Section 13, and taking into account any lost or reduced tax deductions on
account of the Gross-Up Payment, shall be equal to the Payment. 
 (c) Gross-Up Limit. Notwithstanding anything herein to the
contrary, to the extent the sum of the Gross-Up Payment and any similar payments to other executives of the Company which the Company may become obligated to make, as determined by the Board in its sole discretion (“Other Gross-Up
Payments”), exceeds an amount equal to $1,000,000 less any similar payments made by the Company, as determined by the Board in its sole discretion, prior to the date of your payment (the “Gross-Up Limit”), your Gross-Up Payment shall
be reduced (but not to an amount less than zero) on a pro-rata basis with the Other Gross-Up Payments, or such other basis as the Board shall determine in its sole discretion, to the extent necessary so that the sum of your Gross-Up Payment and the
Other Gross-Up Payments does not exceed the Gross-Up Limit (the amount of such reduction, the “Gross-Up Reduction”). 
  

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 (d) Alternative Reduced Payment. Notwithstanding anything in this Section 13 to the
contrary, if the amount equal to the (i) the sum of the Payment and the Gross Up Payment (ii) less the Gross-Up Reduction, as calculated on an after-tax basis taking into account federal, state and local income tax as well as any Parachute Excise
Tax, is less than such reduced amount of the Payments that would result in no portion of such Payments being subject to any Parachute Excise Tax, as calculated on an after-tax basis taking into account federal, state and local income tax, then you
shall not be entitled to any Gross-Up Payment and the Payments shall be reduced to the extent necessary so that no portion of the Payments are subject to any Parachute Excise Tax. 
 (e) Measurements and Adjustments. The determination of the amount of the Payments and whether and to what extent a Gross-Up Payment is
required to be made or the Payments required to be reduced will be made at the Company’s expense by an independent public accountant(s) selected by the Company (the “Accountants”), which Accountants shall provide you and the Company
with detailed supporting calculations with respect to such Gross-Up Payment within a reasonable period of time following the receipt of notice from you or the Company that you have received or will receive a Payment that is potentially subject to
the Parachute Excise Tax. For the purposes of determining whether any Payments will be subject to the Parachute Excise Tax and the amount of such Parachute Excise Tax, such payments will be treated as “parachute payments” within the
meaning of Section 280G of the Code, and all “parachute payments” in excess of the “base amount” (as defined under Section 280G(b)(3) of the Code) shall be treated as subject to the Parachute Excise tax, unless and except to the
extent that in the opinion of the Accountants such Payments (in whole or in part) either do not constitute “parachute payments” or represent reasonable compensation for services actually rendered (within the meaning of Section 280G(b)(4)
of the Code) in excess of the “base amount,” or such “parachute payments” are otherwise not subject to such Parachute Excise Tax. For purposes of determining the amount of the Gross-Up Payment, you will be deemed to pay federal
income taxes at the highest applicable marginal rate of federal income taxation for the calendar year in which the Gross-Up Payment is to be made and to pay any applicable state and local income taxes at the highest applicable marginal rate of
taxation for the calendar year in which the gross-up payment is to be made, net of the maximum reduction in federal income taxes which could be obtained from the deduction of such state or local taxes if paid in such year (determined without regard
to limitations on deductions based upon the amount of your adjusted gross income); and to have otherwise allowable deductions for federal, state and local income tax purposes at least equal to those disallowed because of the inclusion of the
Gross-Up Payment in your adjusted gross income. Any Gross-Up Payment with respect to any Payment shall be paid by the Company at the time you are entitled to receive the Payment. Any determination by the Accountants shall be binding upon you and the
Company. 
 14. RETURN OF MATERIALS. At the termination of your relationship with the Company, you will
promptly return to the Company, and will not take with you or use, all items of any nature that belong to the Company, and all materials (in any form, format, or medium) containing or relating to the Company’s business. 
 15. NONSOLICITATION. You agree that for one (1) year following the termination of your employment, you will not, either directly or through
others, solicit or attempt to solicit any employee, consultant or independent contractor of the Company to terminate his or her relationship with the Company in order to become an employee, consultant or independent contractor to or for any other
person or business entity. 
  

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 16. INDEMNIFICATION. You shall be entitled to continued coverage under your indemnification
agreement with the Company. You shall also be entitled to enter into an indemnification agreement with the Company containing terms acceptable to the Company and consistent with the terms of any such indemnification agreement between the Company and
similarly situated senior executives. 
 17. SECTION 409A. This Agreement shall be interpreted, construed and administered in a
manner that satisfies the requirements of Section 409A of the Code and the final and proposed Department of Treasury Regulations promulgated thereunder. Any payments scheduled to be made hereunder in installments shall be made over a period
equal to the shorter of (a) the period specified for such payment in this Agreement and (b) the period beginning on the date of your termination of employment and ending on March 15 of the year following the year of your termination
of employment with the last payment equal to the sum of the installments which but for this clause (b) would be paid to you. If notwithstanding the preceding sentence, any payment scheduled to be made hereunder would result in tax liability
under Section 409A of the Code, such payment shall be delayed to the extent necessary for this Agreement and such payment to not result in tax liability under Section 409A of the Code and the final (or, if not yet final, the latest
proposed) Department of Treasury Regulations thereunder. Any payments delayed pursuant to this Section 17 shall be paid to you in a lump sum as soon as administratively practicable following such delay. 
 18. ENTIRE AGREEMENT. This Agreement, including Exhibit A, your Proprietary Information and Inventions Agreement, any
indemnification agreement between you and the Company and any indemnification agreement that may be entered into between you and the Company in the future, constitutes the complete, final and exclusive embodiment of the entire agreement between you
and the Company with respect to the terms and conditions of your employment specified herein. If you enter into this Agreement you are doing so voluntarily, and without reliance upon any promise, warranty or representation, written or oral, other
than those expressly contained herein. This Agreement supersedes any other such promises, warranties, representations or agreements. This Agreement may not be amended or modified except by a written agreement signed by you and the CEO. 

19. SEVERABILITY. Whenever possible, each provision of this Agreement will be interpreted in such manner as to be effective and valid under
applicable law, but if any provision of this Agreement is held to be invalid, illegal or unenforceable in any respect under any applicable law or rule in any jurisdiction, such invalidity, illegality or unenforceability will not affect any other
provision of this Agreement, but such invalid, illegal or unenforceable provision will be reformed, construed and enforced so as to render it valid, legal, and enforceable consistent with the intent of the parties insofar as possible. 
 20. BINDING NATURE. This Agreement will be binding upon and inure to the benefit of the personal representatives and successors of
the respective parties hereto. 
  

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 21. GOVERNING LAW. This Agreement will be governed by and construed in accordance
with the laws of the State of California. 
 22. DISPUTE RESOLUTION. To ensure the timely and economical resolution of
disputes that arise in connection with your employment with the Company, you and the Company agree that any and all disputes, claims, or causes of action arising from or relating to the enforcement, breach, performance or interpretation of this
Agreement, your employment, or the termination of your employment, shall be resolved to the fullest extent permitted by law by final, binding and confidential arbitration, by a single arbitrator, in San Francisco, California, conducted by Judicial
Arbitration and Mediation Services, Inc. (“JAMS”) under the applicable JAMS employment rules. By agreeing to this arbitration procedure, both you and the Company waive the right to resolve any such dispute through a trial by jury or
judge or administrative proceeding. The arbitrator shall: (a) have the authority to compel adequate discovery for the resolution of the dispute and to award such relief as would otherwise be permitted by law; and (b) issue a written
arbitration decision, to include the arbitrator’s essential findings and conclusions and a statement of the award. The arbitrator shall be authorized to award any or all remedies that you or the Company would be entitled to seek in a court of
law. The Company shall pay all JAMS’ arbitration fees. Nothing in this Agreement is intended to prevent either you or the Company from obtaining injunctive relief in court to prevent irreparable harm pending the conclusion of any such
arbitration. Notwithstanding the foregoing, you and the Company each have the right to resolve any issue or dispute over intellectual property rights by Court action instead of arbitration. Except as may otherwise be provided for by law, as
determined by the arbitrator, each party shall pay its own attorneys’ fees and costs in an action taken under this Section 22. 
 23.
RIGHT TO WORK. As required by law, this Agreement is subject to satisfactory proof of your right to work in the United States. 
 [Signature Page Follows] 
  

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 If you choose to accept this Agreement under the terms described above, please sign below and return this
letter to me. 
 We look forward to your favorable reply, and to a productive and enjoyable work relationship. 
  

	
	Very truly yours,
	
	Renovis, Inc.
	
	Corey Goodman, Ph.D.
	President and Chief Executive Officer

 Accepted and Agreed to by: 
  

			
	 	  	 
	[Name of Executive Officer]	  	Date

  

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 Exhibit A 
 STOCK OPTION AND EQUITY-BASED AWARD GRANTS 
  

									
	 Date of
 Grant
	 	 Type of
 Grant
	 	 Number of
 Shares
	 	 Exercise
 Price
	 	 Cancelled

		 		 		 		 	
		 		 		 		 	
		 		 		 		 	
		 		 		 		 	
		 		 		 		 	
		 		 		 		 	
		 		 		 		 	
		 		 		 		 	
		 		 		 		 	
		 		 		 		 	
		 		 		 		 	
		 		 		 		 	

 For the purposes of this Exhibit A, “ISO” shall mean “incentive stock option”
within the meaning of Section 422 of the Code, “NQO” shall mean a stock option that is not an ISO and “DSU” shall mean a deferred stock unit award. 
  

 11Form of Deferred Stock Unit Award Grant Notice and Agreement

 Exhibit 10.3 
 RENOVIS, INC. 
 2003 STOCK PLAN, AS AMENDED 
 DEFERRED STOCK UNIT AWARD GRANT NOTICE AND 
 DEFERRED STOCK AWARD AGREEMENT 
 (SECTION 16 OFFICERS) 
 Renovis, Inc., a Delaware corporation, (the “Company”), pursuant to its 2003 Stock Plan, as amended, (the “Plan”), hereby grants to the individual listed below
(“Participant”), an award of units of Deferred Stock (“Deferred Stock Units” or “DSUs”) with respect to the number of shares of Stock set forth below (the
“Shares”). This Deferred Stock Unit Award is subject to all of the terms and conditions as set forth herein and in the Deferred Stock Unit Award Agreement attached hereto as Exhibit A (the “Deferred Stock
Unit Agreement”) and the Plan, each of which are incorporated herein by reference. Unless otherwise defined herein, the terms defined in the Plan shall have the same defined meanings in this Grant Notice and the Deferred Stock Unit
Agreement. 
  

			
	Participant:	  	                                      
                                        
                          
	Grant Date:	  	                        ,
200    
	Vesting Commencement Date:	  	
	Total Number of DSUs:	  	                                      
                                        
             Shares
	Vesting Schedule:	  	         of the Deferred Stock Units shall vest for each calendar month of service after the Vesting Commencement Date, such that all of the
Deferred Stock Units are vested on                        , subject to Participant’s continued employment or service
with the Company or its Subsidiaries through the applicable vesting date. Pursuant to the terms of the Deferred Stock Unit Agreement, vesting of the DSUs may be accelerated in the event that Participant’s employment is terminated without
“Cause” (as defined in the Deferred Stock Unit Agreement) or there is a “Constructive Termination” (as defined in the Deferred Stock Unit Agreement) of Participant’s employment. In no event shall any Deferred Stock Units
vest following Participant’s termination of employment or service with the Company or its Subsidiaries (“Separation from Service”).

 By Participant’s signature and the Company’s signature below, Participant agrees to be bound by the
terms and conditions of the Plan, the Deferred Stock Unit Agreement and this Grant Notice. Participant has reviewed the Deferred Stock Unit Agreement, the Plan and this Grant Notice in their entirety, has had an opportunity to obtain the advice of
counsel prior to executing this Grant Notice and fully understands all provisions of this Grant Notice, the Deferred Stock Unit Agreement and the Plan. Participant hereby agrees to accept as binding, conclusive and final all decisions or
interpretations of the Company upon any questions arising under the Plan, this Grant Notice or the Deferred Stock Unit Agreement. 
  

							
	RENOVIS, INC.:	 	PARTICIPANT:
				
	By:	 	  
	 	By:	 	  

	Print Name:	 	  
	 	Print Name:	 	  

	Title:	 	  
	 		 	
	Address:	 	  
	 	Address:	 	  

		 	  
	 		 	  

 EXHIBIT A 
 TO DEFERRED STOCK UNIT AWARD GRANT NOTICE 
 RENOVIS, INC. DEFERRED STOCK UNIT AWARD AGREEMENT

 (SECTION 16 OFFICERS) 
 Pursuant to
the Deferred Stock Unit Award Grant Notice (the “Grant Notice”) to which this Deferred Stock Unit Award Agreement (the “Agreement”) is attached, Renovis, Inc., a Delaware corporation (the
“Company”) has granted to Participant the right to receive the number of Deferred Stock Units under the 2003 Stock Plan, as amended from time to time (the “Plan”), as set forth in the Grant Notice. The
Award is subject to the terms and conditions of the Plan which are incorporated herein by reference. In the event of any inconsistency between the Plan and this Agreement, the terms of the Plan shall control. 
 1. Grant of the DSUs. As set forth in the Grant Notice, the Company hereby grants the Participant DSUs in exchange for past and future services to
the Company subject to all the terms and conditions in this Agreement, the Grant Notice and the Plan. However, no Shares shall be issued to the Participant until the time set forth in Section 4. Prior to actual payment of any Shares, such DSUs
will represent an unsecured obligation of the Company, payable only from the general assets of the Company. 
 2. Definitions. All
capitalized terms used in this Agreement without definition shall have the meanings ascribed to them in the Plan and the Grant Notice. Whenever used herein, the following terms shall have their respective meanings set forth below: 
 (a) “Acceleration Period” means [twelve (12)][eighteen (18)] months. 
 (b) “Cause” means: (i) theft, dishonesty or falsification of any employment or Company records; (ii) malicious or
reckless disclosure of the Company’s confidential or proprietary information; (iii) commission of any immoral or illegal act or any gross or willful misconduct, where the Company reasonably determines that such act or misconduct has
(A) seriously undermined the ability of the Company’s management to entrust Participant with important matters or otherwise work effectively with Participant, (B) contributed to the Company’s loss of significant revenues or
business opportunities, or (C) significantly and detrimentally affected the business or reputation of the Company or any of its subsidiaries; and/or (iv) Participant’s breach of Participant’s employment agreement with the Company
or the failure or refusal by Participant to work diligently to perform tasks or achieve goals reasonably requested by the Board, provided such breach, failure or refusal continues after the receipt of reasonable notice in writing of such failure or
refusal and an opportunity to correct the problem. “Cause” shall not mean a physical or mental disability. 
 (c)
“Change in Control” means the consummation of any of the following transactions: 
 (i) the closing of a business
combination (such as a merger or consolidation) of the Company with any other corporation or other type of business entity (such as a limited liability company), other than a business combination which would result in the voting securities of the
Company outstanding immediately prior thereto continuing to represent (either by remaining outstanding or by being converted into voting securities of the surviving entity) more than fifty percent (50%) of the total voting power represented by
the voting securities of the Company or such controlling surviving entity outstanding immediately after such business combination; or 
 (ii) the sale, lease, exchange or other transfer or disposition by the Company of all or substantially all (more than seventy percent (70%)) of the Company’s assets by value; or 

 (iii) an acquisition of any voting securities of the Company by any “person” (as the term
“person” is used for purposes of Section 13(d) or Section 14(d) of the Exchange Act) immediately after which such person has “beneficial ownership” (within the meaning of Rule 13d-3 promulgated under the Exchange Act)
of more than fifty percent (50%) of the combined voting power of the Company’s then outstanding voting securities. 
 (d)
“Constructive Termination” means Participant’s resignation within sixty (60) days of one or more of the following events which remains uncured thirty (30) days after Participant’s delivery of written
notice thereof: 
 (i) the delegation to Participant of duties or the reduction of Participant’s duties, either of which substantially
reduces the nature, responsibility, or character of Participant’s position immediately prior to such delegation or reduction; 
 (ii) a
material reduction by the Company in Participant’s base salary in effect immediately prior to such reduction; 
 (iii) a material
reduction by the Company in the kind or level of employee benefits or fringe benefits to which Participant was entitled prior to such reduction; or the taking of any action by the Company that would adversely affect Participant’s participation
in any plan, program or policy generally applicable to employees of equivalent seniority; and 
 (iv) the Company’s requiring
Participant to relocate Participant’s office to a place more than forty (40) miles from the Company’s present headquarters location (except that required travel on the Company’s business to an extent substantially consistent with
Participant’s present business travel obligations shall not be considered a relocation). 
 (e) “Release” means
a general release of all claims against the Company, in a form provided by and reasonably acceptable to the Company. 
 3. Acceleration of
Vesting. 
 (a) Termination By The Company Without Cause. If Participant’s employment by the Company is terminated by the
Company without Cause, or if there is a Constructive Termination, in each case at any time prior to the occurrence of a Change in Control or in each case more than thirteen (13) months following the occurrence of a Change in Control, and if
Participant provides the Company with a signed Release, and does not revoke the Release within the applicable revocation period, if any, then effective as of Participant’s date of termination, Participant shall immediately become vested with
respect to those DSUs that would have vested during the Acceleration Period following Participant’s date of termination. 
 (b)
Termination Following Change in Control. If Participant’s employment by the Company is terminated by the Company without Cause, or if there is a Constructive Termination, in each case at any time within thirteen (13) months
following the occurrence of a Change in Control, and if Participant provides the Company with a signed Release and does not revoke the Release within the applicable revocation period, if any, then effective as of Participant’s date of
termination, Participant shall immediately become 100% vested with respect to all unvested DSUs; provided, further, however, that if Participant’s employment is thereafter terminated by the Company’s successor or acquiror without Cause, or
if there is a Constructive Termination, in each case at any time within thirteen (13) months following the occurrence of the Change in Control, Participant shall be entitled to the acceleration of vesting described above in this subsection (b).

 4. Issuance of Stock. 
 (a) Timing of Distribution. Shares shall be issued to the Participant with respect to vested DSUs as soon as administratively practicable after
the earliest to occur of the following: (i) a date specified by the Company that is between January 1 and March 15 of the calendar year following the calendar year of the vesting date, (ii) the Participant’s Separation from
Service, (iii) the Participant’s Disability, (iv) the Participant’s death, or (v) a Change in Control. 
 (b)
General. Shares issued pursuant to this Section 4 shall be issued (either in book-entry form or otherwise) to the Participant or the Participant’s beneficiaries, as the case may be. No fractional Shares shall be issued under this
Agreement. In the event Participant ceases to be an Employee, consultant to the Company or member of the Board the DSUs shall cease vesting immediately upon such cessation of service and any unvested DSUs awarded by this Agreement shall be
forfeited. 
 5. Taxes. Notwithstanding anything to the contrary in this Agreement, the Company shall be entitled to require payment
to the Company or any of its Subsidiaries any sums required by federal, state or local tax law to be withheld with respect to the issuance of the Deferred Stock Units, the distribution of shares of Stock with respect thereto, or any other taxable
event related to the Deferred Stock Units. The Company may permit the Participant to make such payment in one or more of the forms specified below: 
 (a) by cash or check made payable to the Company; 
 (b) by the deduction of such amount from other compensation payable to
Participant; 
 (c) in the sole discretion of the Company, by requesting that the Company withhold a net number of vested Shares otherwise
issuable having a then current Fair Market Value not exceeding the amount necessary to satisfy the withholding obligation of the Company and its Subsidiaries based on the minimum applicable statutory withholding rates for federal, state, local and
foreign income tax and payroll tax purposes; or 
 (d) in any combination of the foregoing. 
 In the event Participant fails to provide timely payment of all sums required by the Company pursuant to this Section 5, the Company shall have the right and
option, but not obligation, to treat such failure as an election by Participant to satisfy all or any portion of his or her required payment obligation by means of requesting the Company to withhold vested Shares otherwise issuable in accordance
with clause (c) above. The Company shall not be obligated to deliver any new certificate representing Shares issuable with respect to the Deferred Stock Units to Participant or Participant’s legal representative unless and until
Participant or Participant’s legal representative shall have paid or otherwise satisfied in full the amount of all federal, state, local and foreign taxes applicable to the taxable income of Participant resulting from the grant of the Deferred
Stock Units, the distribution of the Shares issuable with respect thereto, or any other taxable event related to the Deferred Stock Units. 
 6. Rights as Stockholder. Neither the Participant nor any person claiming under or through the Participant will have any of the rights or privileges of a stockholder of the Company in respect of any Shares deliverable hereunder
unless and until certificates representing such Shares (which may be in book entry form) will have been issued and recorded on the records of the Company or its transfer agents or registrars, and delivered to the Participant (including through
electronic delivery to a brokerage account). After such issuance, recordation and delivery, the Participant will have all the rights of a stockholder of the Company with respect to voting such Shares and receipt of dividends and distributions on
such Shares. 

 7. Conditions to Issuance of Certificates. Notwithstanding any other provision of this Agreement,
the Company shall not be required to issue or deliver any certificate or certificates for any Shares prior to the fulfillment of all of the following conditions: (A) the admission of the Shares to listing on all stock exchanges on which such
Shares are then listed, (B) the completion of any registration or other qualification of the Shares under any state or federal law or under rulings or regulations of the Securities and Exchange Commission or other governmental regulatory body,
which the Company shall, in its sole and absolute discretion, deem necessary and advisable, (C) the obtaining of any approval or other clearance from any state or federal governmental agency that the Company shall, in its absolute discretion,
determine to be necessary or advisable and (D) the lapse of any such reasonable period of time following the date the DSUs vest as the Company may from time to time establish for reasons of administrative convenience. 
 8. Award Not Transferable. This grant and the rights and privileges conferred hereby will not be transferred, assigned, pledged or hypothecated in
any way (whether by operation of law or otherwise) and will not be subject to sale under execution, attachment or similar process. Upon any attempt to transfer, assign, pledge, hypothecate or otherwise dispose of this grant, or any right or
privilege conferred hereby, or upon any attempted sale under any execution, attachment or similar process, this grant and the rights and privileges conferred hereby immediately will become null and void. 
 9. Not a Contract of Employment. Nothing in this Agreement or in the Plan shall confer upon the Participant any right to continue to serve as an
Employee or other service provider of the Company or any of its subsidiaries. 
 10. Governing Law. The laws of the State of Delaware
shall govern the interpretation, validity, administration, enforcement and performance of the terms of this Agreement regardless of the law that might be applied under principles of conflicts of laws. 
 11. Conformity to Securities Laws. The Participant acknowledges that the Plan and this Agreement are intended to conform to the extent necessary
with all provisions of the Securities Act of 1933, as amended, and the Exchange Act, and any and all regulations and rules promulgated thereunder by the Securities and Exchange Commission, including without limitation Rule 16b-3 under the Exchange
Act. Notwithstanding anything herein to the contrary, the Plan shall be administered, and the Awards are granted, only in such a manner as to conform to such laws, rules and regulations. To the extent permitted by applicable law, the Plan and this
Agreement shall be deemed amended to the extent necessary to conform to such laws, rules and regulations. 
 12. Amendment, Suspension and
Termination. To the extent permitted by the Plan, this Agreement may be wholly or partially amended or otherwise modified, suspended or terminated at any time or from time to time by the Committee or the Board, provided, that, except as
may otherwise be provided by the Plan, no amendment, modification, suspension or termination of this Agreement shall adversely effect the Award in any material way without the prior written consent of the Participant. 
 13. Notices. Notices required or permitted hereunder shall be given in writing and shall be deemed effectively given upon personal delivery or
upon deposit in the United States mail by certified mail, with postage and fees prepaid, addressed to the Participant to his address shown in the Company records, and to the Company at its principal executive office. 

 14. Successors and Assigns. The Company may assign any of its rights under this Agreement to
single or multiple assignees, and this Agreement shall inure to the benefit of the successors and assigns of the Company. Subject to the restrictions on transfer herein set forth, this Agreement shall be binding upon Participant and his or her
heirs, executors, administrators, successors and assigns. 
 15. Compliance in Form and Operation. This Agreement and the Deferred
Stock Units are intended to comply with Section 409A of the Code and the Treasury Regulations thereunder and shall be interpreted in a manner consistent with that intention.

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