Document:

Stock Purchase Agreement

 Exhibit 10.55 
 STOCK PURCHASE AGREEMENT 
 STOCK PURCHASE AGREEMENT, dated as of November 23, 2005
(this “Agreement”), between ANTARES PHARMA, INC., a Delaware corporation (the “Company”), and SICOR PHARMACEUTICALS, INC. (the “Investor”). 
 RECITALS: 
 A. The Investment. The Company intends to sell to the
Investor, and the Investor intends to purchase from the Company, as an investment in the Company, the securities as described herein. The securities to be purchased are common stock, par value $0.01 per share, of the Company (the “Common
Stock” or “Common Shares”) and are to be purchased at the Closing, as defined below, subject to the terms and conditions set forth herein. 
 B. The Securities. The term “Securities” refers to the Common Stock purchased under this Agreement. 
 C. Transaction Documents. The term “Transaction Documents” refers collectively to this Agreement and the registration-related provisions contained in Exhibit 1. 
 NOW, THEREFORE, in consideration of the premises, and of the representations, warranties, covenants and agreements set forth herein, the parties
agree as follows: 
 ARTICLE I 
 Purchase; Closings 
 1.1 Purchase. On the terms and subject to the conditions set forth herein, at the Closing, the
Investor will purchase from the Company, and the Company will sell to the Investor the Securities as set forth in Section 1.2. 
 1.2
Closing. (a) At the closing (the “Closing”), the Investor will purchase from the Company, and the Company will sell to the Investor, 400,000 Common Shares at a per share price of $1.25 per share ($500,000 in the
aggregate) (the “Purchase”). The Closing will take place at the offices of [Leonard, Street and Deinard Professional Association, 150 South Fifth Street, Suite 2300, Minneapolis, Minnesota 55402] 10:00 a.m., [ Minneapolis] time, on
_________ __, 2005. 
 (b) (1) The respective obligations of each of the Investor and the Company to consummate the Closing is
subject to the fulfillment or written waiver by the Investor and the Company prior to the Closing of the following conditions: (A) all approvals and authorizations of, filings and registrations with, and notifications to, all governmental or
regulatory authorities, agencies, courts, commissions or other entities (collectively, “Governmental Entities”) required for the Purchase shall have been obtained or made and shall be in full force and effect and all other waiting
periods shall have expired, in each case, without imposing or the Company agreeing to any restriction or condition that would have a 

 
Material Adverse Effect, as defined below, on the Company; and (B) no provision of any applicable law or regulation and no judgment, injunction, order
or decree shall prohibit the Purchase or shall prohibit or restrict Investor or its Affiliates, as defined below, from owning or voting any Securities, as defined below. 
 (2) The obligation of the Company to consummate the Closing is also subject to the fulfillment or written waiver prior to the Closing of
the following conditions: the Investor shall have performed in all material respects all obligations required to be performed by it under this Agreement at or prior to the Closing and the Company shall have received a certificate dated as of the
Closing Date signed on behalf of the Investor by a senior officer or general partner certifying compliance with Section 1.2(b)(2) hereof. 
 (3) The obligation of the Investor to consummate the Closing is also subject to the fulfillment or written waiver prior to the Closing of each of the following conditions: the Company shall have performed in all
material respects all obligations required to be performed by it under this Agreement at or prior to the Closing and the Investor shall have received a certificate dated as of the Closing Date signed on behalf of the Company by a senior officer
certifying compliance with Section 1.2(b)(3) hereof. 
 ARTICLE II 
 Representations and Warranties 
 2.1 Disclosure. (a) On or prior to
the date hereof, the Company delivered to the Investor a schedule (“Disclosure Schedule”) setting forth, among other things, items the disclosure of which is necessary or appropriate either in response to an express disclosure
requirement contained in a provision hereof or as an exception to one or more of the Company’s representations or warranties contained in Section 2.2 or to one or more of its covenants contained in Article III; provided that the
mere inclusion of an item in a Disclosure Schedule as an exception to a representation or warranty will not be deemed an admission by the Company that such item represents a material exception or fact, event or circumstance or that such item is
reasonably likely to result in a Material Adverse Effect. 
 (b) “Material Adverse Effect” means, with
respect to the Investor only clause (2) that follows, or, with respect to the Company, both clauses (1) and (2) that follow, any circumstance, event, change or effect that: (1) is material and adverse to the financial position,
results of operations, business, assets or liabilities of the Company and its subsidiaries taken as a whole or (2) would materially impair the ability of either the Investor or the Company, respectively, to perform its obligations under this
Agreement or otherwise materially threaten or materially impede the consummation of the Purchase and the other transactions contemplated by this Agreement; provided, however, that Material Adverse Effect, under clause (1) or (2), shall
be deemed not to include the impact of (A) changes in generally accepted accounting principles, (B) changes in laws of general applicability or interpretations thereof by Governmental Entities, (C) actions or omissions of either party
taken with the prior written consent of the other party in contemplation of the transactions contemplated hereby, (D) changes or conditions (including changes in economic, financial market, regulatory or 

 
political conditions, whether resulting from acts of war or terrorism, an escalation of hostilities or otherwise) affecting the U.S. economy or foreign
economies (so long as any such change in condition does not disproportionately affect the business of the Company and its subsidiaries) and (E) this Agreement, the transactions contemplated hereby and thereby or the announcement thereof.

 (c) “Previously Disclosed” means information set forth on the section of the Disclosure Schedule
corresponding to the provision of this Agreement to which such information relates; provided that information which, on its face, reasonably should indicate to the reader that it relates to another provision of this Agreement shall also be
deemed to be Previously Disclosed with respect to such other provision, as otherwise disclosed on a Company Report, as defined below, filed prior to the date hereof (other than as set forth in the risk factors or forward looking statements of such
Company Report). 
 2.2 Representations and Warranties of the Company. Except as Previously Disclosed, the Company represents and
warrants to the Investor that: 
 (a) Organization and Authority. The Company is a corporation duly organized, validly
existing and in good standing under the laws of the State of Delaware, is duly qualified to do business and is in good standing in all jurisdictions where its ownership or leasing of property or the conduct of its business requires it to be so
qualified and failure to be so qualified would have a Material Adverse Effect on the Company and has corporate power and authority to own its properties and assets and to carry on its business as it is now being conducted. The Company has furnished
to the Investor true and correct copies of the Certificate of Incorporation and Bylaws of the Company as amended through the date of this Agreement. 
 (b) Company’s Subsidiaries. The Company has Previously Disclosed a complete and correct list of all of its subsidiaries as of the date hereof, all shares of the outstanding capital stock of each of which
are owned directly or indirectly by the Company. The material subsidiaries of the Company are referred to herein individually as a “Company Subsidiary” and collectively as the “Company Subsidiaries.” No equity
security of any Company Subsidiary is or may be required to be issued by reason of any option, warrant, scrip, preemptive right, right to subscribe to, call or commitment of any character whatsoever relating to, or security or right convertible
into, shares of any capital stock of such Company Subsidiary, and there are no contracts, commitments, understandings or arrangements by which any Company Subsidiary is bound to issue additional shares of its capital stock, or any option, warrant or
right to purchase or acquire any additional shares of its capital stock. All of such shares so owned by the Company are fully paid and nonassessable and are owned by it free and clear of any lien, claim, charge, option, encumbrance or agreement with
respect thereto. Other than the Company Subsidiaries or as Previously Disclosed, the Company does not own beneficially (the concept of “beneficial ownership” having the meaning assigned thereto in Section 13(d) of the Securities
Exchange Act of 1934 (the “Exchange Act”), and the rules and regulations thereunder), directly or indirectly, more than 5% of any class of equity securities or similar interests of any corporation or other entity, and is not,
directly or indirectly, a partner in any partnership or party to any joint venture. 

 (c) Capitalization. The authorized capital stock of the Company consists of
100 million shares of Common Stock, of which 42,379,486 shares were outstanding as of the date of this Agreement. As of the date hereof, there are outstanding options (each, a “Company Stock Option”) to purchase an aggregate of
not more than 3,500,000 shares of Common Stock. The maximum number of shares of Common Stock that would be outstanding as of the Closing Date if all options, warrants, committed grants, conversion rights and other rights with respect thereto
(excluding those to be issued pursuant hereto) outstanding as of the date hereof were exercised is not more than 63,500,000. All of the outstanding shares of capital stock of the Company have been duly and validly authorized and issued and are fully
paid and nonassessable. The shares of Common Stock to be issued in accordance with the terms of this Agreement, upon such issuance, will be duly and validly authorized and issued and fully paid and nonassessable. Except as Previously Disclosed, as
of the date hereof there are no outstanding subscriptions, contracts, conversion privileges, options, warrants, calls, preemptive rights or other rights obligating the Company to issue, sell or otherwise dispose of, or to purchase, redeem or
otherwise acquire, any shares of capital stock of the Company. 
 (d) Authorization; No Default. The Company has the
power and authority to enter into this Agreement and to carry out its obligations hereunder and thereunder. The execution, delivery and performance of this Agreement by the Company and the consummation of the transactions contemplated hereby have
been duly authorized by the Board of Directors of the Company (the “Board of Directors”). This Agreement represents a valid and binding obligation of the Company, enforceable against the Company in accordance with its terms, except
as enforceability may be limited by bankruptcy, insolvency, moratorium, reorganization or other similar laws affecting the enforcement of creditors’ rights generally and to judicial limitations on the remedy of specific enforcement and other
equitable remedies. 
 Neither the execution, delivery and performance by the Company of this Agreement and any documents
ancillary hereto, nor the consummation of the transactions contemplated hereby and thereby, nor compliance by the Company with any of the provisions hereof or thereof, will (1) violate, conflict with, or result in a breach of any provision of,
or constitute a default (or an event which, with notice or lapse of time or both, would constitute a default) under, or result in the termination of, or accelerate the performance required by, or result in a right of termination or acceleration of,
or result in the creation of, any lien, security interest, charge or encumbrance upon any of the properties or assets of the Company under any of the material terms, conditions or provisions of (A) its Certificate of Incorporation or Bylaws or
(B) any note, bond, mortgage, indenture, deed of trust, license, lease, agreement to which the Company is a party or by which it may be bound, or to which the Company or any of the properties or assets of the Company may be subject, or
(2) violate any statute, rule or regulation or, to the knowledge of the Company, any judgment, ruling, order, writ, injunction or decree applicable to the Company or any of their respective properties or assets; except, in the case of clauses
(1)(B) and (2), as would not reasonably be likely to have a Material Adverse Effect on the Company. 

 (e) Consents. Other than filing a Form D with the SEC, as defined below, and
related filings to be made by the Company., no notice to, filing with, exemption or review by, or authorization, consent or approval of, any Governmental Entity or any other person is necessary for the consummation by the Company of the transactions
contemplated by this Agreement. 
 (f) Company Financial Statements. The consolidated balance sheets of the Company and
its subsidiaries as of December 31, 2004 and 2003 and related consolidated statements of income, stockholders’ equity and cash flows for the three years ended December 31, 2004, together with the notes thereto, certified by KPMG LLP
and included in the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2004 (the “Company 10-K”) as filed with the Securities and Exchange Commission (the “SEC”), and the unaudited
consolidated balance sheets of the Company and its subsidiaries as of June 30, 2005 and related consolidated statements of income, stockholders’ equity and cash flows for the quarter then ended, included in the Company’s Quarterly
Report on Form 10-Q for the period ended June 30, 2005 (collectively, the “Company Financial Statements”) have been prepared in accordance with generally accepted accounting principles applied on a consistent basis and present
fairly the consolidated financial position of the Company and its subsidiaries at the dates and the consolidated results of operations and cash flows of the Company and its subsidiaries for the periods stated therein (subject to the absence of notes
and year-end audit adjustments in the case of interim unaudited statements). 
 (g) Reports. Since December 31,
2004, the Company has filed all material reports, registrations and statements, together with any required amendments thereto, that it was required to file with the SEC, including, but not limited to, Forms 10-K, Forms 8-K, Forms 10-Q and proxy
statements and any documents incorporated by reference therein. All such reports and statements filed with any such regulatory body or authority are collectively referred to herein as the “Company Reports”. As of their respective
dates, the Company Reports (1) complied in all material respects with all the rules and regulations promulgated by the SEC and (2) did not contain any untrue statement of a material fact or omit to state a material fact required to be
stated therein or necessary in order to make the statements therein not misleading. Copies of all the Company Reports (other than those which have been filed with the SEC and are publicly available on EDGAR) have been made available to the Investor
by the Company. 
 (h) Properties and Leases. Except for any lien for current taxes not yet delinquent or which are
being contested in good faith and by appropriate proceedings and except as Previously Disclosed, the Company has good title free and clear of any material liens, claims, charges, options, encumbrances or similar restrictions to all the real and
personal property reflected in the Company’s consolidated balance sheet as of December 31, 2004 included in the Company 10-K for the period then ended, and all real and personal property acquired since such date, except such real and
personal property as has been disposed of in the ordinary course of business. Except as is not reasonably likely to have a Material Adverse Effect on the Company, all leases of real property and all other leases material to the Company pursuant to
which the Company, as lessee, leases real or personal property are valid and effective in accordance with their respective terms, and 

 
there is not, under any such lease, any material existing default by the Company or any event which, with notice or lapse of time or both, would constitute
such a material default. 
 (i) Taxes. Each of the Company has filed all material federal, state, county, local and
foreign tax returns, including information returns, required to be filed by it, and paid all material taxes owed by it, including those with respect to income, withholding, social security, unemployment, workers compensation, franchise, ad valorem,
premium, excise and sales taxes, and no taxes shown on such returns to be owed by it or assessments received by it are delinquent. The federal income tax returns of the Company for the fiscal year ended December 31, 1997 are for the purposes of
routine audit by the Internal Revenue Service (the “IRS”) closed because of the statute of limitations, and no claims for additional taxes for such fiscal years are pending. The Company is not a party to any pending action or
proceeding, nor to the Company’s knowledge has any such action or proceeding been threatened by any Governmental Entity, for the assessment or collection of taxes, interest, penalties, assessments or deficiencies that would reasonably be likely
to have a Material Adverse Effect on the Company and, to the knowledge of the Company, no issue has been raised by any federal, state, local or foreign taxing authority in connection with an audit or examination of the tax returns, business or
properties of the Company which has not been settled, resolved and fully satisfied, or adequately reserved for (other than those issues that are not reasonably likely to have a Material Adverse Effect on the Company). The Company has withheld all
material taxes that it is required to withhold from amounts owing to employees, creditors or other third parties. 
 (j) No
Material Adverse Effect. Since December 31, 2004, no change has occurred and no circumstances exist which have had or are reasonably likely to have a Material Adverse Effect on the Company. 
 (k) Commitments and Contracts. The Company has Previously Disclosed or has filed as an exhibit to a Company Report filed prior to
the date hereof (or with respect to clause (4) below only, made available to the Investor or its representative) each of the following to which the Company is a party or subject (whether written or oral, express or implied): 
 (1) any material contract, agreement or arrangement (including severance arrangements) the terms of which would be subject to violation,
breach, default, termination, acceleration of performance, or which would result in the creation of any lien, security interest, charge or encumbrance, as a result of the execution, delivery and performance by the Company of this Agreement or any
documents ancillary hereto, or the consummation of the transactions contemplated hereby or thereby; 
 (2) any material
contract, agreement or arrangement providing for “earn-outs,” “savings guarantees,” “performance guarantees,” or other contingent payments (other than in the ordinary course of the operating businesses of the Company,
such as rebates and obligations under operating leases, triple net leases and indemnification arrangements in favor of directors and employees) by 

 
the Company other than those with respect to which there are no further material obligations under such provisions; 
 (3) any contract purporting to limit in any material respect, or containing covenants that would have the effect of limiting in any
material respect, the ability of any Affiliate of the Company (other than Company Subsidiaries) to compete in any line of business or with any person or which involve any restriction of the geographical area in which, or method by which or with
whom, such Affiliate may carry on its business (other than as may be required by law or applicable regulatory authorities); or 
 (4) any real property lease and any other lease which commits the Company to make at any time after the date hereof payments aggregating $5,000,000 or more. 
 (l) Litigation and Other Proceedings. There is no pending or, to the knowledge of the Company, threatened, claim, action, suit,
investigation or proceeding, against the Company, nor is the Company subject to any order, judgment or decree, except for matters that have not had a Material Adverse Effect or are not reasonably likely to have a Material Adverse Effect. 

(m) Compliance with Laws. The Company has all permits, licenses, authorizations, orders and approvals of, and have made all
filings, applications and registrations with, Governmental Entities that are required in order to permit it to own or lease its properties and assets and to carry on its business as presently conducted and that are material to the business of the
Company and the Company Subsidiaries, taken as a whole; and all such permits, licenses, certificates of authority, orders and approvals are in full force and effect and, to the knowledge of the Company, no suspension or cancellation of any of them
is threatened, and all such filings, applications and registrations are current. Except as is not reasonably likely to have a Material Adverse Effect on the Company, (A) the conduct by the Company of its business and the condition and use of
its properties does not violate or infringe any applicable domestic (federal, state or local) or foreign law, statute, ordinance, license or regulation, and (B) the Company is not in default under any order, license, regulation, demand, writ,
injunction or decree of any Governmental Entity. 
 (n) No Defaults. The Company is not in default, nor has any event
occurred that, with the passage of time or the giving of notice, or both, would constitute a default, under any material agreement, indenture, loan agreement or other instrument to which it is a party or by which it or any of its assets is bound or
to which any of its assets is subject, the result of which is reasonably likely to have a Material Adverse Effect on the Company. 
 (o) Brokers and Finders. Neither the Company nor any of its officers, directors or employees has employed any broker or finder or incurred any liability for any financial advisory fees, brokerage fees, commissions or finder’s
fees, and no broker or finder has 

 
acted directly or indirectly for the Company, in connection with this Agreement or the transactions contemplated hereby. 
 2.3 Representations and Warranties of the Investor. The Investor hereby represents and warrants to the Company that: 
 (a) Organization and Authority. The Investor is a corporation duly organized, validly existing and in good standing under the laws
of the jurisdiction of its organization, is duly qualified to do business and is in good standing in all jurisdictions where its ownership or leasing of property or the conduct of its business requires it to be so qualified and failure to be so
qualified would have a Material Adverse Effect on the Investor and has full corporate power and authority to own its properties and assets and to carry on its business as it is now being conducted. The Investor has furnished the Company with a true
and correct copy of its certificate of incorporation and bylaws, as amended through the date of this Agreement. 
 (b)
Authorization. The Investor has the power and authority to enter into this Agreement and to carry out its obligations hereunder. The execution, delivery and performance of this Agreement by the Investor and the consummation of the
transactions contemplated hereby have been duly authorized by the Investor’s board of directors and no further approval or authorization is required. Subject to such approvals of Governmental Entities as may be required by statute or
regulation, this Agreement is a valid and binding obligation of the Investor, enforceable against the Investor in accordance with its terms. 
 Neither the execution, delivery and performance by the Investor of this Agreement, nor the consummation of the transactions contemplated hereby, nor compliance by the Investor with any of the provisions hereof, will
(1) violate, conflict with, or result in a breach of any provision of, or constitute a default (or an event which, with notice or lapse of time or both, would constitute a default) under, or result in the termination of, or accelerate the
performance required by, or result in a right of termination or acceleration of, or result in the creation of, any lien, security interest, charge or encumbrance upon any of the properties or assets of the Investor under any of the material terms,
conditions or provisions of (A) its certificate of incorporation or bylaws or (B) any material note, bond, mortgage, indenture, deed of trust, license, lease, agreement or other instrument or obligation to which the Investor is a party or
by which it may be bound, or to which the Investor or any of the properties or assets of the Investor may be subject, or (2) subject to compliance with the statutes and regulations referred to in the next paragraph, materially violate any
statute, rule or regulation or, to the knowledge of the Investor, any judgment, ruling, order, writ, injunction or decree applicable to the Investor or any of its properties or assets. 
 No notice to, filing with, exemption or review by, or authorization, consent or approval of, any Governmental Entity or any other person
is necessary for the consummation by the Investor of the transactions contemplated by this Agreement. 

 (c) Knowledge as to Conditions. As of the date of this Agreement, it knows of no
reason why any regulatory approvals and, to the extent necessary, any other approvals, authorizations, filings, registrations, or notices required or otherwise a condition to the consummation of the transactions contemplated by this Agreement
cannot, or should not, be obtained. 
 (d) Purchase for Investment. The Investor acknowledges that the Securities have
not been registered under the Securities Act of 1933, as amended, and the rules and regulations thereunder (the “Securities Act”) or under any state securities laws. The Investor (1) is acquiring the Securities for its own
account pursuant to an exemption from registration under the Securities Act solely for investment and not with a view to distribution in violation of applicable securities laws, (2) will not sell or otherwise dispose of any of the Securities,
except in compliance with the registration requirements or exemption provisions of the Securities Act and any other applicable securities laws, (3) has such knowledge and experience in financial and business matters and in investments of this
type that it is capable of evaluating the merits and risks of its investment in the Securities and of making an informed investment decision and (4) is an Accredited Investor (as that term is defined by Rule 501 of the Securities Act).

 (e) Financial Capability. The Investor will have available funds to make the Purchase on the terms and conditions
contemplated by this Agreement. 
 (f) Brokers and Finders. Neither the Investor nor its Affiliates or any of their
respective officers, directors or employees has employed any broker or finder or incurred any liability for any financial advisory fees, brokerage fees, commissions or finder’s fees, and no broker or finder has acted directly or indirectly for
the Investor, in connection with this Agreement or the transactions contemplated hereby. 
 ARTICLE III 
 Covenants 
 3.1 Filings; Other
Actions. (a) Each of the Investor and the Company will cooperate and consult with the other and use commercially reasonable best efforts to prepare and file all necessary documentation, to effect all necessary applications, notices,
petitions, filings and other documents, and to obtain all necessary permits, consents, orders, approvals and authorizations of, or any exemption by, all third parties and Governmental Entities necessary or advisable to consummate the transactions
contemplated by this Agreement. Each of the Investor and the Company will have the right to review in advance, and to the extent practicable each will consult with the other, in each case subject to applicable laws relating to the exchange of
information, with respect to all the information relating to the other party, and any of their respective subsidiaries, which appears in any filing made with, or written materials submitted to, any third party or any Governmental Entity in
connection with the transactions contemplated by this Agreement. In exercising the foregoing right, each of the parties hereto agrees to act reasonably and as promptly as practicable. Each party hereto agrees to keep the other party apprised of the
status of matters relating to completion of the transactions contemplated hereby. 

 
Nothing in this Section shall apply to the reports or other filings made by the Company and or pursuant to the Exchange Act. 
 (a) Information and Confidentiality. The Investor will hold, and will cause its respective subsidiaries and their directors,
officers, employees, agents, consultants and advisors to hold, in strict confidence, unless compelled to disclose by judicial or administrative process or, in the written opinion of its counsel, by other requirement of law or the applicable
requirements of any regulatory agency or relevant stock exchange, all records, books, contracts, instruments, computer data and other data and information (collectively, “Information”) concerning the Company or any Company
Subsidiary, in each case, furnished to it by or on behalf of the Company, any Company Subsidiary or its respective representatives (except to the extent that such information can be shown to have been (1) previously known by the Investor on a
non-confidential basis, (2) in the public domain through no fault of the Investor or (3) later lawfully acquired from other sources by the Investor), and the Investor shall not release or disclose such Information to any other person,
except its to auditors, attorneys, financial advisors, and other consultants and advisors who owe the Investor an obligation of confidentiality no less stringent that the one set forth above. 
 ARTICLE IV 
 Additional Agreements 
 4.1 Registration Rights. The Company shall use its commercially reasonable best efforts to file with the SEC, on behalf of the Investor and its
Affiliates and any subsequent transferee, a registration statement (the “Registration Statement”) covering the Registrable Securities purchased hereunder; provided that in no event shall the Company fail to file the Registration Statement
later than the 90th day following the date hereof, provided that the Company may, upon written notice to the Investor, elect to delay the filing of the Registration Statement for up to six (6) months if it believes, in good faith, that it would
be in the best interests of the Company to do so. The expenses of the preparation and filing of such Registration Statement shall be borne by the Company. Upon filing the Registration Statement, the Company will use its commercially reasonable best
efforts to have declared effective as soon as reasonably practicable following the filing thereof and to keep the Registration Statement effective with the SEC at all times until the Investor or any transferee who would require such registration to
effect a sale of the Registrable Securities no longer holds the Registrable Securities, unless all such Registrable Securities then held by such holder can immediately be sold and for at least 30 of the past 60 trading days could have been sold by
such holder pursuant to Rule 144 under the Securities Act. Provisions relating to the registration rights discussed in this Section are included in Exhibit 1 hereto. “Registrable Securities” means all shares of Common Stock acquired by the
Investor hereunder. 

 4.2 Legend. (a) The Investor agrees that all certificates or other instruments representing
the Securities subject to this Agreement will bear a legend substantially to the following effect: 
 “THE SECURITIES
REPRESENTED BY THIS INSTRUMENT HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR SECURITIES LAWS OF ANY STATE AND MAY NOT BE TRANSFERRED, SOLD OR OTHERWISE DISPOSED OF EXCEPT WHILE A REGISTRATION STATEMENT RELATING THERETO IS
IN EFFECT UNDER SUCH ACT AND APPLICABLE STATE SECURITIES LAWS OR PURSUANT TO AN EXEMPTION FROM REGISTRATION UNDER SUCH ACT OR SUCH LAWS. 
 (b) Upon request of the Investor to effect a sale of any Securities, upon receipt by the Company of an opinion of counsel reasonably satisfactory to the Company to the effect that the Investor or its transferee is not
an “affiliate” and has not been an “affiliate” (within the meaning of Rule 144 promulgated under the Securities Act) for the preceding three months, and otherwise subject to compliance with the provisions of Rule 144(k)
promulgated under the Securities Act, the Company shall promptly cause any legend to be removed from any certificate for any Securities so to be Transferred. The Investor acknowledges that the Securities have not been registered under the Securities
Act or under any state securities laws and agrees that it will not sell or otherwise dispose of any of the Securities, except in compliance with the registration requirements or exemption provisions of the Securities Act and any other applicable
securities laws. 
 4.3 Withholding. The Company shall be entitled to deduct and withhold from amounts payable to the Investor or any
of its Affiliate funds in respect of the Securities such amounts as it is required to deduct and withhold under applicable law. To the extent that amounts are so withheld by the Company, such withheld amounts shall be treated for all purposes as
having been paid to the Investor or any such Affiliate fund in respect of which such deduction and withholding was made by the Company. Prior to the Investor or any of its Affiliate funds receiving any Securities, the Investor shall, and cause such
Affiliate fund to, deliver to the Company a duly executed IRS Form W-9 or the appropriate IRS Form W-8, as applicable, and such other IRS forms as may reasonably requested by the Company from time to time. The Investor shall, and cause such
Affiliate fund to, update all such IRS Forms, as appropriate, from time to time. 
 ARTICLE V 
 Miscellaneous 
 5.1 Survival of
Representations, Warranties, Agreements, Etc. Each of the representations and warranties set forth in this Agreement shall survive the Closing but only for a period of 18 months following the Closing Date and thereafter shall expire and have no
further force and effect. Except as otherwise provided herein, all covenants and agreements contained herein shall survive for the duration of any statutes of limitations applicable thereto or until, by their respective terms, they are no longer
operative. 
 5.2 Amendment. No amendment or waiver of any provision of this Agreement will be effective with respect to any party
unless made in writing and signed by an officer of a duly authorized representative of such party. 

 5.3 Waiver. The conditions to each party’s obligation to consummate the Purchase are for the
sole benefit of such party and may be waived by such party in whole or in part to the extent permitted by applicable law. No waiver will be effective unless it is in a writing signed by a duly authorized officer of the waiving party that makes
express reference to the provision or provisions subject to such waiver. 
 5.4 Counterparts and Facsimile. For the convenience of the
parties hereto, this Agreement may be executed in any number of separate counterparts, each such counterpart being deemed to be an original instrument, and all such counterparts will together constitute the same agreement. Executed signature pages
to this Agreement may be delivered by facsimile and such facsimiles will be deemed as sufficient as if actual signature pages had been delivered. 
 5.5 Governing Law; Jurisdiction. This Agreement will be governed by and construed in accordance with the laws of the State of Delaware applicable to contracts made and to be performed entirely within such State. The parties
hereby irrevocably and unconditionally consent to submit to the exclusive jurisdiction of the state and federal courts located in the State of Delaware for any actions, suits or proceedings arising out of or relating to this Agreement and the
transactions contemplated hereby 
 5.6 WAIVER OF JURY TRIAL. EACH OF THE PARTIES HERETO HEREBY IRREVOCABLY WAIVES ANY AND ALL
RIGHT TO TRIAL BY JURY IN ANY LEGAL PROCEEDING ARISING OUT OF OR RELATED TO THIS AGREEMENT OR THE TRANSACTIONS CONTEMPLATED HEREBY. 
 5.7 Notices. Any notice, request, instruction or other document to be given hereunder by any party to the other will be in writing and will be deemed to have been duly given (a) on the date of delivery if delivered personally or
by telecopy or facsimile, upon confirmation of receipt, (b) on the first business day following the date of dispatch if delivered by a recognized next-day courier service, or (c) on the third business day following the date of mailing if
delivered by registered or certified mail, return receipt requested, postage prepaid. All notices hereunder shall be delivered as set forth below, or pursuant to such other instructions as may be designated in writing by the party to receive such
notice. 
 (a) If to the Investor: 
  

			
		  	SICOR Pharmaceuticals, Inc.
		  	19 Hughes
		  	Irvine, California 92618
		  	Attention: Senior Vice President and General Manager
		
	with a copy to:	  	Teva North America
		  	425 Privet Road
		  	Horsham, PA 19044
		  	Attention: Senior Vice President and General Counsel

			
		  	Willkie Farr & Gallagher LLP
		  	787 Seventh Avenue
		  	New York, New York 10019-6099
		  	Telecopy: (212) 728-8111

					
		  	Attn:	  	William J. Grant, Jr.
		  		  	Jeffrey S. Hochman

 (b) If to the Company: 
  

			
		  	Antares Pharma, Inc.
		  	707 Eagleview Boulevard, Suite 414
		  	 Exton, Pennsylvania 19341

		  	 Attention: President and Chief Executive Officer

		
	with a copy to:	  	Leonard, Street and Deinard Professional Association
	(which shall not	  	150 South Fifth Street
	constitute notice	  	Suite 2300
	to the Company)	  	Minneapolis, MN 55402
		  	Telecopy: (612) 335-1657
		  	Attention: Morris M. Sherman, Esq.

 5.8 Entire Agreement, Etc. (a) This Agreement (including Disclosure Schedule)
constitute the entire agreement between the parties with respect to the subject matter hereof, and supersede all other prior agreements, understandings, representations and warranties, both written and oral, between the parties, with respect to the
subject matter hereof, and (b) this Agreement will not be assignable by operation of law or otherwise (any attempted assignment in contravention hereof being null and void). 
 5.9 Definitions of “subsidiary,” “Affiliate” and “knowledge”. (a) When a reference is made in this Agreement to
a subsidiary of a person, the term “subsidiary” means those corporations and other entities of which such person owns or controls more than 50% of the outstanding equity securities either directly or through an unbroken chain of
entities as to each of which more than 50% of the outstanding equity securities is owned directly or indirectly by its parent; provided, however, that there shall not be included any such entity to the extent that the equity securities of
such entity were acquired in satisfaction of a debt previously contracted in good faith or are owned or controlled in a bona fide fiduciary capacity. 
 (b) The term “Affiliate” means, with respect to any person, any person directly or indirectly controlling, controlled by
or under common control with, such other person. For purposes of this definition, “control” when used with respect to any person, means the possession, directly or indirectly, of the power to cause the direction of management and/or
policies of such person, whether through the ownership of voting securities by contract or otherwise. 
 (c) The term
“knowledge” or any similar formulation of knowledge shall mean, (i) in the case of the Company, the actual knowledge after due inquiry of an executive officer of the Company (which due inquiry shall include reasonable inquiry
of the direct reports to such executive officer and appropriate senior executives of the Company Subsidiaries) and (ii)

 
in the case of the Investor, the actual knowledge after due inquiry of a managing director of the entity that manages the Investor. 
 5.10 Captions. The Article, Section and paragraph captions herein are for convenience of reference only, do not constitute part of this Agreement
and will not be deemed to limit or otherwise affect any of the provisions hereof. 
 5.11 Severability. If any provision of this
Agreement or the application thereof to any person (including, without limitation, the officers and directors of the Investor and the Company) or circumstance is determined by a court of competent jurisdiction to be invalid, void or unenforceable,
the remaining provisions hereof, or the application of such provision to persons or circumstances other than those as to which it has been held invalid or unenforceable, will remain in full force and effect and shall in no way be affected, impaired
or invalidated thereby, so long as the economic or legal substance of the transactions contemplated hereby is not affected in any manner materially adverse to any party. Upon such determination, the parties shall negotiate in good faith in an effort
to agree upon a suitable and equitable substitute provision to effect the original intent of the parties. 
 5.12 No Third Party
Beneficiaries. Nothing contained in this Agreement, expressed or implied, is intended to confer upon any person or entity other than the parties hereto or permitted transferees of the Investor, any benefit right or remedies. 
 5.13 Time of Essence. Time is of the essence in the performance of each and every term of this Agreement. 
 5.14 Specific Performance. The transactions contemplated by this Agreement are unique. Accordingly, the Company and the Investor acknowledge and
agree that, in addition to all other remedies to which it may be entitled, each of the parties hereto is entitled to a decree of specific performance, provided that such party hereto is not in material default hereunder. The parties hereto agree
that, if for any reason a party shall have failed to perform its obligations under this Agreement, then the party seeking to enforce this Agreement against such nonperforming party shall be entitled to specific performance and injunctive and other
equitable relief, and the parties further agree to waive any requirement for the securing or posting of any bond in connection with the obtaining of any such injunctive or other equitable relief. This provision is without prejudice to any other
rights that any party may have against another party for any failure to perform its obligations under this Agreement, including the right to seek damages for a material breach of any provision of this Agreement. 

 IN WITNESS WHEREOF, this Agreement has been duly executed and delivered by the duly authorized
officers of the parties hereto as of the date first herein above written. 
  

			
	ANTARES PHARMA, INC.
		
	By:	 	 /s/ Jack E. Stover

		 	 Name: Jack E. Stover

		 	 Title:  President and CEO

	
	SICOR PHARMACEUTICALS, INC.
		
	By:	 	 /s/ Mark Durand

		 	 Name: Mark Durand

		 	 Title: CFO and SVP

 Suspension of Registration Statement. Anything in this Agreement to the contrary notwithstanding, it
is understood and agreed that the Company shall not be required to keep any shelf registration effective or useable for offers and sales of the Registrable Securities, file a post effective amendment to a shelf registration statement or prospectus
supplement or to supplement or amend any registration statement, if (A) the Registration Statement, any prospectus or prospectus supplement constituting a part thereof, or any document incorporated by reference in any of the foregoing contains
an untrue statement of a material fact or omits to state any material fact required to be stated therein or necessary to make the statements therein not misleading, in the light of the circumstances under which they are made; (B) the Company is
in possession of material information that it deems advisable not to disclose in a Registration Statement; (C) the Company has determined to proceed with a public offering of its equity securities and, in the judgment of the managing
underwriter thereof or the Company (if such offering is not underwritten), sales under the Registration Statement would have a material adverse effect on such offering; or (D) the Company is engaged in any program for the purchase of shares of
its own Common Stock, unless such repurchase program and the requested sale may proceed concurrently pursuant to an exemption under the Commission’s Regulation M or any other applicable exemption (it being understood that, to the extent
consistent with any such program, the Company will use commercially reasonable efforts to make an exemption available to the beneficiaries of these registration rights (the “Beneficiaries”) or to otherwise open up a sufficient
window period under Regulation M to enable the Beneficiary to obtain the liquidity it desires hereunder). The Company shall provide notice of any such suspension to the Investor and each Beneficiary in accordance with Section 5.7 of this
Agreement. Upon receipt by a Beneficiary of notice of an event of the kind, described in this Section 1, such Beneficiary shall forthwith discontinue such Beneficiary’s disposition of Registrable Securities until the Company has provided
notice that such disposition may continue and of any supplemented or amended prospectus indicated in such notice. The Company agrees that any period in which sales, transfers or dispositions must be discontinued as a result of a given occurrence of
a circumstance referred to in the preceding sentence shall not exceed 60 days, and shall not exceed 120 days in the aggregate over any 12-month period. 

 Indemnification by the Company. The Company agrees to indemnify and hold harmless each Beneficiary, its officers
and directors, and each person, if any, who controls such Beneficiary, within the meaning of either Section 15 of the Securities Act or Section 20 of the Exchange Act, from and against any and all losses, claims, damages and liabilities
(including, without limitation, any legal or other expenses reasonably incurred by such Beneficiary, any of its officers or directors or any such controlling person in connection with defending or investigating any such action or claim) caused by
any untrue statement or alleged untrue statement of a material fact contained in the Registration Statement or any prospectus relating to Registrable Securities (as amended or supplemented if the Company shall have furnished any amendments or
supplements thereto) or any preliminary prospectus, or caused by any omission or alleged omission to state therein a material fact required to be stated therein or necessary to make the statements therein, in light of the circumstances under which
they were made, not misleading, except insofar as such losses, claims, damages or liabilities are caused by any such untrue statement or omission or alleged untrue statement or omission based upon information furnished by such Beneficiary or the
plan of distribution, furnished in writing to the Company by or on behalf of such Beneficiary expressly for use therein; provided, however, that the foregoing indemnity agreement with respect to any prospectus shall not inure to the
benefit of such Beneficiary if a copy of the most current prospectus at the time of the delivery of the securities was made available to such Beneficiary but was not provided by the Beneficiary or any Underwriter to the buyer of such securities and
such current prospectus would have cured the defect giving rise to such loss, claim, damage or liability. The Company also agrees to indemnify any Underwriters of any Registrable Securities, their officers and directors and each person who controls
such Underwriters on substantially the same basis as that of the indemnification of Beneficiary provided in this Section 2. As used throughout this Exhibit, “Underwriter” means a securities dealer who purchases any Registrable
Securities as principal and not as part of such dealer’s market-making activities. 
 Indemnification by Each Beneficiary. Each Beneficiary
agrees, severally and not jointly, to indemnify and hold harmless the Company, its officers and directors, and each person, if any, who controls the Company within the meaning of either Section 15 of the Securities Act or Section 20 of the
Exchange Act to the same extent as the foregoing indemnity from the Company to such Beneficiary, but only with reference to information furnished by such Beneficiary or the plan of distribution furnished in writing by or on behalf of such
Beneficiary expressly for use in the Registration Statement or any prospectus relating to the Registrable Securities, or any amendment or supplement thereto or any preliminary prospectus. Each Beneficiary also agrees, severally and not jointly to
indemnify and hold harmless any Underwriters of the Registrable Securities, their officers and directors, and each person who controls such underwriters on substantially the same basis as that of the indemnification of the Company provided in this
Section 3. Notwithstanding anything to the contrary contained in this Exhibit, the obligations of any Beneficiary pursuant to this Section 3 shall not exceed the amount of proceeds received by such Beneficiary for the relevant Registrable
Securities. 
 Conduct of Indemnification Proceedings. In case any proceeding (including any governmental investigation) shall be instituted involving
any person in respect of which indemnity may be sought pursuant to Section 2 or 3 of this Exhibit, such person (the “Indemnified Party”) shall promptly notify the person against whom such indemnity may be sought (the
“Indemnifying Party”) in writing and the Indemnifying Party, upon the request of the Indemnified Party, shall retain counsel reasonably satisfactory to such Indemnified Party to represent such Indemnified 

 
Party and any others the Indemnifying Party may designate in such proceeding and shall pay the fees and disbursements of such counsel related to such
proceeding. In any such proceeding, any Indemnified Party shall have the right to retain its own counsel (which counsel shall be reasonably accountable to the Indemnifying Party), but the fees and expenses of such counsel shall be at the expense of
such Indemnified Party unless (a) the Indemnifying Party and the Indemnified Party shall have mutually agreed in writing to the retention of such counsel or (b) the named parties to any such proceeding (including any impleaded parties)
include both the Indemnified Party and the Indemnifying Party and, in the written opinion of counsel for the Indemnified Party, representation of both parties by the same counsel would be inappropriate due to actual or potential conflicts of
interests between them. It is understood that the Indemnifying Party shall not, in connection with any proceeding or related proceedings involving one or more Indemnified Parties in the same jurisdiction, be liable for the fees and expenses of more
than one separate firm of attorneys (in addition to any local counsel required under the circumstances) at any time for all such Indemnified Parties, and that all such fees and expenses shall be reimbursed as they are submitted in writing for
payment. In the case of any such separate firm for the Indemnified Parties, such firm shall be designated in writing by the Indemnified Parties or, if the Indemnified Parties are exclusively Beneficiaries, by the Investor. The Indemnifying Party
shall not be liable for any settlement of any proceeding effected without its written consent, but if settled with such consent, or if there be a final judgment for the plaintiff, the Indemnifying Party shall indemnify and hold harmless such
Indemnified Parties from and against any loss or liability (to the extent stated above) by reason of such settlement or judgment. 
 Contribution. If
the indemnification provided for in this Exhibit is unavailable to an Indemnified Party in respect of any losses, claims, damages or liabilities referred to herein, then each such Indemnifying Party, in lieu of indemnifying such Indemnified Party,
shall contribute to the amount paid or payable by such Indemnified Party as a result of such losses, claims, damages or liabilities (a) in such proportion as is appropriate to reflect the relative benefits received by the Company, Beneficiary
and the Underwriters from the offering of the securities, or (b) if the allocation provided by clause (a) above is not permitted by applicable law, in such proportion as is appropriate to reflect not only the relative benefits referred to
in clause (a) above but also the relative fault of the Company, such Beneficiary and the Underwriters in connection with the statements or omissions that resulted in such losses, claims, damages or liabilities, as well as any other relevant
equitable considerations. The relative benefits received by the Company, such Beneficiary and the Underwriters shall be deemed to be in the same respective proportions as the total proceeds from the offering (net of underwriting discounts and
commissions but before deducting expenses) received by each of the Company and such Beneficiary and the total underwriting discounts and commissions received by the Underwriters, in each case as set forth in the table on the cover page of the
prospectus, bear to the aggregate public offering price of the securities. The relative fault of the Company, such Beneficiary and the Underwriters shall be determined by reference to, among other things, whether the untrue or alleged untrue
statement of a material fact or the omission or alleged omission to state a material fact relates to information supplied by such party and the parties’ relative intent, knowledge, access to information and opportunity to correct or prevent
such statement or omission. 
 The Company and each Beneficiary agrees that it would not be just and equitable if contribution pursuant to this
Section 5 were determined by pro rata allocation (even if the Underwriters were treated as one entity for such purpose) or by any other method of allocation that does not take account of the equitable considerations referred to in the
immediately preceding paragraph. The 

 
amount paid or payable by an Indemnified Party as a result of the losses, claims, damages or liabilities referred to in the immediately preceding paragraph
shall be deemed to include, subject to the limitations set forth above, any legal or other expenses reasonably incurred by such Indemnified Party in connection with investigating or defending any such action or claim. Notwithstanding the provisions
of this Section 5, no Underwriter shall be required to contribute any amount in excess of the amount by which the total price at which the securities underwritten by it and distributed to the public were offered to the public exceeds the amount
of any damages which such Underwriter has otherwise been required to pay by reason of such untrue or alleged untrue statement or omission or alleged omission, and each Beneficiary shall not be required to contribute any amount in excess of the
amount by which the net proceeds of the offering (before deducting expenses) received by such Beneficiary exceeds the amount of any damages which such Beneficiary has otherwise been required to pay by reason of such untrue or alleged untrue
statement or omission or alleged omission. No person guilty of fraudulent misrepresentation (within the meaning of Section 11(f) of the Securities Act) shall be entitled to contribution from any person who was not guilty of such fraudulent
misrepresentation. 
 Survival. The indemnity and contribution agreements contained in this Exhibit shall remain operative and in full force and
effect regardless of (a) any termination of this Agreement or any underwriting agreement, (b) any investigation made by or on behalf of any Indemnified Person or by or on behalf of the Company and (c) the consummation of the sale or
successive resales of the Registrable Securities. 
 Registration Expenses. In connection with the Registrable Securities, the Company shall pay the
following reasonable expenses incurred in connection with such registration: (a) registration and filing fees with the Commission, (b) fees and expenses of compliance with securities or blue sky laws (including reasonable fees and
disbursements of counsel in connection with blue sky qualifications of the Registrable Securities), (c) printing expenses, (d) fees and expenses incurred in connection with the listing of the Registrable Securities on the stock exchanges,
if any, on which the applicable class of Registrable Securities is then listed or, if such class of Registrable Securities is not then listed, on the principal national stock exchange on which the Common Stock is then listed, (e) fees and
expenses of counsel and independent certified public accountants for the Company (including the expenses of any comfort letters reasonably required by any Underwriters), (f) the fees and expenses of any additional experts retained by the
Company in connection with such registration and (g) fees and expenses in connection with any review of underwriting arrangements by the National Association of Securities Dealers, Inc. Each Beneficiary shall pay any underwriting fees,
discounts or commissions attributable to the sale of Registrable Securities by it and any out-of-pocket expenses of such Beneficiary, including its counsel fees, accountant fees and expenses. The Company shall pay internal Company expenses
(including, without limitation, all salaries and expenses of its officers and employees performing legal or accounting duties).Form of Common Stock and Warrant Purchase Agreement

 Exhibit 10.57 
  

 COMMON STOCK AND WARRANT PURCHASE AGREEMENT 
 by and among 
 Antares Pharma, Inc.

 and 
 the parties named herein
on Schedule 1, as Purchasers 
 February 27, 2006 
  

 This COMMON STOCK AND WARRANT PURCHASE AGREEMENT (this “Agreement”) is dated as
of February 27, 2006, among Antares Pharma, Inc., a Delaware corporation (the “Company”), and the purchasers identified on Schedule 1 hereto (each a “Purchaser” and collectively the
“Purchasers”). 
 WHEREAS, subject to the terms and conditions set forth in this Agreement and pursuant to Section 4(2)
of the Securities Act (as defined below), and Rule 506 promulgated thereunder, the Company desires to issue and sell to the Purchasers, and the Purchasers, severally and not jointly, desire to purchase from the Company in the aggregate, 8,770,000
shares of Common Stock, and Warrants to purchase 6,577,500 shares of Common Stock. 
 NOW, THEREFORE, in consideration of the mutual
covenants contained in this Agreement, and for other good and valuable consideration the receipt and adequacy of which are hereby acknowledged, the Company and each Purchaser agree as follows: 
 ARTICLE I 
 DEFINITIONS 
 1.1 Certain Definitions; Terms of Warrants. 
 In addition to the terms defined elsewhere in this Agreement, for all purposes of this Agreement, the following terms have the meanings indicated in this Section 1.1: 
 “Action” shall have the meaning ascribed to such term in Section 3.1(j). 
 “Affiliate” means any Person that, directly or indirectly through one or more intermediaries, controls or is controlled by or is under
common control with a Person, as such terms are used in and construed under Rule 144. With respect to a Purchaser, any investment fund or managed account that is managed on a discretionary basis by the same investment manager as such Purchaser will
be deemed to be an Affiliate of such Purchaser. 
 “Agreement” shall have the meaning ascribed to such term in the Preamble.

 “Business Day” means any day except Saturday, Sunday and any day which is a federal legal holiday or a day on which
banking institutions in the Commonwealth of Pennsylvania are authorized or required by law or other governmental action to close. 
 “Closing” shall have the meaning ascribed to such term in Section 2.1(a). 
 “Closing Date”
shall have the meaning ascribed to such term in Section 2.1(a). 
 “Closing Escrow Agreement” shall have the meaning
ascribed to such term in Section 2.1(b). 
 “Commission” means the Securities and Exchange Commission. 

 “Common Stock” means the common stock of the Company, $0.01 par value per share, and any
securities into which such common stock may hereafter be reclassified. 
 “Common Stock Equivalents” means any securities of
the Company or the Subsidiaries which would entitle the holder thereof to acquire at any time Common Stock, including without limitation, any debt, preferred stock, rights, options, warrants or other instrument that is at any time convertible into
or exchangeable for, or otherwise entitles the holder thereof to receive, Common Stock. 
 “Company” shall have the meaning
ascribed to such term in the Preamble. 
 “Disclosure Schedules” means the Disclosure Schedules concurrently delivered
herewith. 
 “Effective Date” means the date that the Registration Statement is first declared effective by the Commission.

 “Environmental Laws” shall have the meaning ascribed to such term in Section 3.1(y). 
 “Exchange Act” means the Securities Exchange Act of 1934, as amended. 
 “FDC Act” shall have the meaning ascribed to such term in Section 3.1(m). 
 “GAAP” shall have the meaning ascribed to such term in Section 3.1(h). 
 “Governmental Authorizations” shall have the meaning ascribed to such term in Section 3.1(m). 
 “Hazardous Substances” shall have the meaning ascribed to such term in Section 3.1(y). 
 “Indemnified Party” shall have the meaning ascribed to such term in Section 5.3. 
 “Indemnifying Party” shall have the meaning ascribed to such term in Section 5.3. 
 “Intellectual Property” shall have the meaning ascribed to such term in Section 3.1(o). 
 “Investor Rights Agreement” means the Investor Rights Agreement, dated as of the date of this Agreement, among the Company and each of
the Purchasers, in the form of Exhibit A hereto. 
 “Lien” means a lien, charge, security interest, encumbrance,
right of first refusal or other restriction, except for a lien for current taxes not yet due and payable and a minor imperfection of title, if any, not material in nature or amount and not materially detracting from the value or impairing the use of
the property subject thereto or impairing the operations or proposed operations of the Company. 
 “Material Adverse Effect”
shall have the meaning ascribed to such term in Section 3.1(b). 
  

 3 

 “Per Share Purchase Price” equals $1.25, subject to adjustment for stock splits, reverse
stock splits, stock dividends, stock combinations and other similar transactions of the Common Stock that occur after the date of this Agreement and prior to Closing. 
 “Person” means an individual or corporation, partnership, trust, incorporated or unincorporated association, joint venture, limited liability company, joint stock company, government (or an agency or
subdivision thereof) or other entity of any kind. 
 “Placement Agent Warrants” means the common stock purchase warrants to
be issued at the Closing to SCO Securities LLC and/or their designees as partial compensation for services rendered in connection with the transaction set forth herein as provided on Schedule 1 attached hereto, which warrants shall be in the
form of Exhibit C hereto. 
 “Premises” shall have the meaning ascribed to such term in Section 3.1(y).

 “Purchase Price” means the aggregate purchase price paid by each Purchaser for the shares of Common Stock and Warrants
purchased by such Purchaser hereunder. 
 “Purchaser” shall have the meaning ascribed to such term in the Preamble.

 “Registration Statement” means a registration statement meeting the requirements set forth in the Investor Rights
Agreement and covering the resale by the Purchasers of the Shares and the Warrant Shares. 
 “Rights” shall have the meaning
ascribed to such term in Section 3.1(o). 
 “Rule 144” means Rule 144 promulgated by the Commission pursuant to the
Securities Act, as such Rule may be amended from time to time, or any similar rule or regulation hereafter adopted by the Commission having substantially the same effect as such Rule. 
 “SEC Reports” shall have the meaning ascribed to such term in Section 3.1(h). 
 “Securities” means the Shares, the Warrants and the Warrant Shares. 
 “Securities Act” means the Securities Act of 1933, as amended. 
 “Shares” means the shares of Common Stock issued to each Purchaser pursuant to this Agreement. 
 “Subscription Amount” means, as to each Purchaser, the amount set forth beside such Purchaser’s name on Schedule 1 hereto,
in United States dollars and in immediately available funds. 
 “Subsidiary” means, with respect to any entity, any
corporation or other organization of which securities or other ownership interest having ordinary voting power to elect a majority of the board of directors or other persons performing similar functions, are directly or indirectly owned by such
entity or of which such entity is a partner or is, directly or indirectly, the beneficial owner of 50% or more of any class of equity securities or equivalent profit participation interests. 

  

 4 

 “Trading Day” means (i) a day on which the Common Stock is traded on a Trading
Market, or (ii) if the Common Stock is not listed on a Trading Market, a day on which the Common Stock is traded on the over-the-counter market, as reported by the OTC Bulletin Board, or (iii) if the Common Stock is not listed on a Trading
Market or quoted on the OTC Bulletin Board, a day on which the Common Stock is quoted in the over-the-counter market as reported by Pink Sheets LLC (or any similar organization or agency succeeding to its functions of reporting prices); provided,
that in the event that the Common Stock is not listed or quoted as set forth in (i), (ii) and (iii) hereof, then Trading Day shall mean a Business Day. 
 “Trading Market” means the following markets or exchanges on which the Common Stock is listed or quoted for trading on the date in question: the American Stock Exchange, the New York Stock Exchange,
the Nasdaq National Market, or the Nasdaq Capital Market. 
 “Transaction Documents” means this Agreement, the Certificate
of Designation, the Investor Rights Agreement, the Warrants and any other documents or agreements executed in connection with the transactions contemplated hereunder. 
 “Warrants” means the Common Stock Purchase Warrants, in the form of Exhibit B hereto. The Placement Agent Warrants shall also constitute “Warrants” for all purposes hereunder and SCO
Securities LLC and/or its designees shall constitute “Purchasers” for all purposes hereunder. 
 “Warrant Shares”
means the shares of Common Stock issuable upon exercise of the Warrants. 
 1.2 Terms of the Warrants. The terms and provisions
of the Warrants are as set forth in the form of Common Stock Purchase Warrant, attached hereto as Exhibit B (and Exhibit C in the case of the Placement Agent Warrants). 
  

 5 

 ARTICLE II 
 PURCHASE AND SALE 
 2.1 Closing. 
 (a) The closing of the transactions contemplated under this Agreement (the “Closing”) will take place as promptly as practicable, but no
later than five (5) Business Days following satisfaction or waiver of the conditions set forth in Sections 2.2 and 2.3 (other than those conditions which by their terms are not to be satisfied or waived until the Closing), at the offices of
Wiggin and Dana LLP, 400 Atlantic Street, Stamford, CT 06901 (or remotely via exchange of documents and signatures) or at such other place or day as may be mutually acceptable to the Purchasers and the Company. The date on which the Closing occurs
is the “Closing Date”. 
 (b) At the Closing, the Purchasers shall purchase, severally and not jointly, and the
Company shall issue and sell, in the aggregate, 8,770,000 shares of Common Stock and Warrants to purchase 6,577,600 shares of Common Stock on the Closing Date. Each Purchaser shall purchase from the Company, and the Company shall issue and sell to
each Purchaser, a number of Shares equal to such Purchaser’s Subscription Amount divided by the Per Share Purchase Price and a Warrant to purchase 75% of the number of Shares purchased by such Purchaser. The Subscription Amount paid by each
Purchaser shall be placed in escrow pending the Closing pursuant to a Closing Escrow Agreement among the Company, SCO Securities LLC and Wiggin and Dana LLP (the “Escrow Agent”), which agreement shall be in the form
attached hereto as Exhibit D (the “Closing Escrow Agreement”). 
 2.2 Conditions to
Obligations of Purchasers to Effect the Closing. 
 The obligations of each Purchaser to effect the Closing and the transactions
contemplated by this Agreement shall be subject to the satisfaction at or prior to the Closing of each of the following conditions, any of which may be waived, in writing, by such Purchaser: 
 (a) At the Closing (unless otherwise specified below) the Company shall deliver or cause to be delivered to each Purchaser the following: 
 (i) this Agreement, duly executed by the Company; 
 (ii) a certificate evidencing a number of Shares equal to such Purchaser’s Subscription Amount divided by the Per Share Purchase Price as set forth on Schedule 1 hereto, registered in the name of such Purchaser; 
 (iii) a Warrant, registered in the name of such Purchaser, pursuant to which such Purchaser shall have the right to acquire up to the number of shares of
Common Stock equal to 75% of the Shares to be issued to such Purchaser at such Closing, as set forth on Schedule 1 hereto; 
 (iv) the
Investor Rights Agreement, duly executed by the Company; 
  

 6 

 (v) a legal opinion of counsel to the Company, in the form of Exhibit E hereto; 
 (vi) a certificate of the Secretary of the Company (the “Secretary’s Certificate”), attaching a true copy of the Certificate of
Incorporation and Bylaws of the Company, as amended to the Closing Date, and attaching true and complete copies of the resolutions of the Board of Directors of the Company authorizing the execution, delivery and performance of this Agreement and the
other Transaction Documents; and 
 (vii) confirmation from the American Stock Exchange or email confirmation from Company counsel that the
American Stock Exchange has approved the application for the listing or qualification of the Shares and the Warrant Shares for trading thereon, subject to official notice of issuance. 
 (b) The Company shall have entered into the Closing Escrow Agreement. 
 (c) All representations and warranties of the Company contained herein shall remain true and correct as of the Closing Date as though such representations and warranties were made on such date (except those
representations and warranties that address matters only as of a particular date will remain true and correct as of such date). 
 (d) As of
the Closing Date, there shall have been no Material Adverse Effect with respect to the Company since the date hereof. 
 (e) From the date
hereof to the Closing Date, trading in the Common Stock shall not have been suspended by the Commission (except for any suspension of trading of limited duration agreed to by the Company, which suspension shall be terminated prior to the Closing),
and, at any time prior to the Closing Date, trading in securities generally as reported by Bloomberg Financial Markets shall not have been suspended or limited, or minimum prices shall not have been established on securities whose trades are
reported by such service, or on any Trading Market, nor shall a banking moratorium have been declared either by the United States or New York State authorities. 
 2.3. Conditions to Obligations of the Company to Effect the Closing. 
 The obligations of the
Company to effect the Closing and the transactions contemplated by this Agreement shall be subject to the satisfaction at or prior to the Closing of each of the following conditions, any of which may be waived, in writing, by the Company.

 (a) At the Closing, each Purchaser shall deliver or cause to be delivered to the Company the following: 
 (i) this Agreement, duly executed by such Purchaser; 
 (ii) such Purchaser’s Subscription Amount, by wire transfer of immediately available funds as provided in the Closing Escrow Agreement; and 
  

 7 

 (iii) the Investor Rights Agreement, duly executed by such Purchaser. 
 (b) All representations and warranties of each of the Purchasers contained herein shall remain true and correct as of the Closing Date as though such
representations and warranties were made on such date. 
 ARTICLE III 
 REPRESENTATIONS AND WARRANTIES 
 3.1 Representations and Warranties
of the Company. 
 Except as set forth under the corresponding section of the Disclosure Schedules delivered concurrently herewith,
the Company hereby makes the following representations and warranties as of the date hereof and as of the Closing Date to each Purchaser: 
 (a) Subsidiaries. Except as listed in Schedule 3.1(a), the Company has no direct or indirect Subsidiaries. 
 (b)
Organization and Qualification. Each of the Company and the Subsidiaries is an entity duly incorporated or otherwise organized, validly existing and in good standing under the laws of the jurisdiction of its incorporation or organization (as
applicable), with the requisite corporate power and authority to own and use its properties and assets and to carry on its business as currently conducted. Neither the Company nor any of its Subsidiaries is in violation of any of the provisions of
its respective certificate or articles of incorporation, bylaws or other organizational or charter documents. Each of the Company and the Subsidiaries is duly qualified to conduct business and is in good standing as a foreign corporation or other
entity in each jurisdiction in which the nature of the business conducted or property owned by it makes such qualification necessary, except where the failure to be so qualified or in good standing, as the case may be, would not have or result in
(i) a material adverse effect on the legality, validity or enforceability of any Transaction Document, (ii) a material adverse effect on the business or financial condition of the Company and the Subsidiaries, taken as a whole, or
(iii) a material adverse effect on the Company’s ability to perform in any material respect on a timely basis its obligations under any Transaction Document (any of (i), (ii) or (iii) being referred to herein as a
“Material Adverse Effect”). 
 (c) Authorization; Enforceability. The Company has the requisite corporate power and
authority to enter into and to consummate the transactions contemplated by each of the Transaction Documents and otherwise to carry out its obligations thereunder. The execution and delivery of each of the Transaction Documents by the Company and
the consummation by it of the transactions contemplated thereby (including, but not limited to, the sale and delivery of the Shares and Warrants) have been duly authorized by all necessary corporate action on the part of the Company and no further
corporate action is required by the Company in connection therewith. The issuance and delivery of Warrant Shares upon exercise of the Warrants has been duly authorized by all necessary action on the part of the Company and no further action is
required by the Company in connection therewith. Each Transaction Document has been (or upon delivery will have been) duly executed by the Company and, when delivered in accordance with the terms hereof, will constitute the valid and binding
obligation of the Company 

  

 8 

 
enforceable against the Company in accordance with its terms, except (i) as limited by laws of general application relating to bankruptcy, insolvency,
reorganization, moratorium or other similar laws affecting creditors’ rights generally, (ii) as limited by rules of law governing specific performance, injunctive relief, or other equitable remedies and (iii) to the extent the
indemnification provisions contained in the Transaction Documents may be limited by applicable federal or state securities laws. 
 (d) No
Conflicts. The execution, delivery and performance of the Transaction Documents by the Company and the consummation by the Company of the transactions contemplated thereby do not and will not (i) conflict with or violate any provision of
the Company’s or any of its Subsidiaries’ certificate or articles of incorporation, bylaws or other organizational or charter documents, or (ii) conflict with, or constitute a default (or an event that with notice or lapse of time or
both would become a default) under, or give to others any rights of termination, amendment, acceleration or cancellation (with or without notice, lapse of time or both) of, any agreement, credit facility, debt or other instrument (evidencing a
Company or its Subsidiary’s debt or otherwise of the Company or any of its Subsidiaries) or other understanding to which the Company or any of its Subsidiaries is a party or by which any property or asset of the Company or any of its
Subsidiaries is bound or affected, or (iii) result in a violation of any law, rule, regulation, order, judgment, injunction, decree or other restriction of any court or governmental authority to which the Company or a of its Subsidiaries is
subject (including federal and state securities laws and regulations), or by which any property or asset of the Company or any of its Subsidiaries is bound or affected, except, in the case of clause (ii), where such conflict, default or violation
would not have or result in a Material Adverse Effect. 
 (e) Filings, Consents and Approvals. The Company is not required to obtain
any consent, waiver, authorization or order of, give any notice to, or make any filing or registration with, any court or other federal, state, local or other governmental authority or other Person in connection with the execution, delivery and
performance by the Company of the Transaction Documents, other than (i) the filing with the Commission of the Registration Statement, the application(s) to each Trading Market for the listing of the Shares and Warrant Shares for trading thereon
in the time and manner required thereby, Form D and applicable Blue Sky filings, and (ii) such as have already been obtained or such exemptive filings as are required to be made under applicable securities laws. 
 (f) Issuance of the Securities. The Securities are duly authorized and, when issued and paid for in accordance with the Transaction Documents,
will be duly and validly issued, fully paid and nonassessable, free and clear of all Liens, other than any Liens created by or imposed on the holders thereof through no action of the Company. The Company has reserved from its duly authorized capital
stock (i) the maximum number of shares of Common Stock issuable pursuant to this Agreement and (ii) the maximum number of shares of Common Stock issuable upon exercise of the Warrants. 
 (g) Capitalization. 
 (i) The entire
authorized capital stock of the Company consists of (A) 100,000,000 shares of Common Stock, 44,591,640 of which are issued and outstanding, and (B) 3,000,000 shares of preferred stock, none of which are issued and outstanding. All shares
of the 

  

 9 

 
Company’s issued and outstanding capital stock have been duly authorized, are validly issued and outstanding, and are fully paid and nonassessable. No
securities issued by the Company from the date of its incorporation to the date hereof were issued in violation of any statutory or common law preemptive rights. There are no dividends which have accrued or been declared but are unpaid on the
capital stock of the Company. All taxes required to be paid by the Company in connection with the issuance and any transfers of the Company’s capital stock have been paid. All securities of the Company have been issued in all material respects
in accordance with the provisions of all applicable securities and other laws. 
 (ii) No Person has any right of first refusal, preemptive
right, right of participation, or any similar right to participate in the transactions contemplated by the Transaction Documents. Except as a result of the purchase and sale of the Securities and except for employee and director stock options under
the Company’s equity compensation plans and for 15,141,381 shares of Common Stock issuable pursuant to outstanding warrants, there are no outstanding options, warrants, rights to subscribe to, calls or commitments of any character whatsoever
relating to, or securities, rights or obligations convertible into or exchangeable for, or giving any Person any right to subscribe for or acquire, any shares of Common Stock, or contracts, commitments, understandings or arrangements by which the
Company or any of its Subsidiaries is or may become bound to issue additional shares of Common Stock, or securities or rights convertible or exchangeable into shares of Common Stock. The issue and sale of the Securities will not obligate the Company
to issue shares of Common Stock or other securities to any Person (other than the Purchasers) and will not result in a right of any holder of Company securities to adjust the exercise, conversion, exchange or reset price under such securities.

 (h) SEC Reports; Financial Statements; Liabilities. 
 (i) The Company has filed all reports required to be filed by it under the Securities Act and the Exchange Act, including pursuant to Section 13(a) or 15(d) of the Exchange Act, for the 12 months preceding the
date hereof (or such shorter period as the Company was required by law to file such material) (the foregoing materials, including the exhibits thereto, being collectively referred to herein as the “SEC Reports”) on a timely basis or
has received a valid extension of such time of filing and has filed any such SEC Reports prior to the expiration of any such extension. As of their respective filing dates, the SEC Reports complied in all material respects with the requirements of
the Securities Act and the Exchange Act, as the case may be, and the rules and regulations of the Commission promulgated thereunder, as applicable, and none of the SEC Reports, as of their respective filing dates, contained any untrue statement of a
material fact or omitted to state a material fact required to be stated therein or necessary in order to make the statements therein, in light of the circumstances under which they were made, not misleading. 
 (ii) The financial statements of the Company included in the SEC Reports comply in all material respects with applicable accounting requirements and the
rules and regulations of the Commission with respect thereto as in effect at the time of filing. Such financial statements have been prepared in accordance with generally accepted accounting principles in the United States, applied on a consistent
basis during the periods involved (“GAAP”), except as may be otherwise specified in such financial statements or the notes thereto and except that unaudited financial statements may not contain all footnotes required by GAAP,
subject to normal year-end 

  

 10 

 
audit adjustments. Such financial statements fairly present in all material respects the financial position of the Company and its consolidated subsidiaries,
if any, as of and for the dates thereof and the results of operations and cash flows for the periods then ended, subject, in the case of unaudited statements, to normal year-end audit adjustments. 
 (iii) Except as set forth in the SEC Reports, and except for liabilities and obligations incurred since December 31, 2004 in the ordinary course of
business, consistent with past practice, as of the date hereof: (i) the Company and its Subsidiaries do not have any material liabilities or obligations (absolute, accrued, contingent or otherwise) and (ii) to the knowledge of the Company,
there has not been any aspect of the prior or current conduct of the business of the Company or its Subsidiaries which would reasonably be expected to form the basis for any material claim by any third party which if asserted would result in a
Material Adverse Effect. 
 (i) Material Changes. Since December 31, 2004 and except as expressly disclosed in the SEC Reports or
as set forth on Schedule 3.1(i), the Company has conducted its business only in the ordinary course, consistent with past practice, and there has not occurred: 
 (i) any event that would have or would reasonably be expected to have a Material Adverse Effect on the Company or any of its Subsidiaries; 
 (ii) any amendments or changes in the charter documents of the Company and its Subsidiaries; 
 (iii) any
damage, destruction or loss, whether or not covered by insurance, that would, individually or in the aggregate, have or would be reasonably likely to have, a Material Adverse Effect on the Company and its Subsidiaries; 
 (iv) any: 
 (A) incurrence, assumption or
guarantee by the Company or its Subsidiaries of any debt for borrowed money other than (i) equipment leases made in the ordinary course of business, consistent with past practice and (ii) any such incurrence, assumption or guarantee with
respect to an amount of $25,000 or less; 
 (B) issuance or sale of any securities convertible into or exchangeable for securities of the
Company other than to directors, employees and consultants pursuant to existing equity compensation or stock purchase plans of the Company; 
 (C) issuance or sale of options or other rights to acquire from the Company or its Subsidiaries, directly or indirectly, securities of the Company or any securities convertible into or exchangeable for any such securities, other than
options issued to directors, employees and consultants in the ordinary course of business, consistent with past practice; 
 (D) issuance or
sale of any stock, bond or other corporate security other than to directors, employees and consultants pursuant to existing equity compensation or stock purchase plans of the Company; 
  

 11 

 (E) discharge or satisfaction of any material Lien on any asset of the Company or any of its
Subsidiaries; 
 (F) declaration or making any payment or distribution to stockholders or purchase or redemption of any share of its capital
stock or other security other than to directors, officers and employees of the Company or any of its Subsidiaries as compensation for services rendered to the Company or its Subsidiary (as applicable) or for reimbursement of expenses incurred on
behalf of the Company or any of its Subsidiary (as applicable); 
 (G) sale, assignment or transfer of any of the intangible assets of the
Company or any of its Subsidiaries except in the ordinary course of business, consistent with past practice, or cancellation of any debt or claim except in the ordinary course of business, consistent with past practice; 
 (H) waiver of any right of substantial value of the Company or any of its Subsidiaries whether or not in the ordinary course of business; 
 (I) material change in officer compensation of the Company or any of its Subsidiaries, except in the ordinary course of business and consistent with
past practice; or 
 (J) other commitment (contingent or otherwise) of the Company or any of its Subsidiaries to do any of the foregoing.

 (v) any creation, sufferance or assumption by the Company or any of its Subsidiaries of any Lien on any asset or any making of any loan,
advance or capital contribution to or investment in any Person, in an aggregate amount which exceeds $25,000 outstanding at any time; 
 (vi)
any entry into, amendment of, relinquishment, termination or non-renewal by the Company or any of its Subsidiaries of any material contract, license, lease, transaction, commitment or other right or obligation, other than in the ordinary course of
business, consistent with past practice; or 
 (vii) any transfer or grant of a right with respect to the patents, trademarks, trade names,
service marks, trade secrets, copyrights or other intellectual property rights owned or licensed by the Company or any of its Subsidiaries, except as between or among the Company and any its Subsidiaries. 
 (j) Litigation. There is no action, suit, inquiry, notice of violation, proceeding or investigation pending or, to the knowledge of the Company or
any of its Subsidiaries, threatened against the Company, any of its Subsidiaries or any of their respective properties before or by any court, arbitrator, governmental or administrative agency or regulatory authority (federal, state, county, local
or foreign) (collectively, an “Action”) which (i) adversely affects or challenges the legality, validity or enforceability of any of the Transaction Documents or the Securities or (ii) would, if there were an unfavorable
decision, have or result in a Material Adverse Effect. Neither the Company nor any of its Subsidiaries, nor, to the knowledge of the Company or any of its Subsidiaries, any director or officer thereof, is or has been the subject of 

  

 12 

 
any Action involving a claim of violation of or liability under federal or state securities laws or a claim of breach of fiduciary duty. To the knowledge of
the Company or any of its Subsidiaries, there has not been and there is not pending or contemplated, any investigation by the Commission involving the Company or any of its Subsidiaries or any current or former director or officer of the Company or
any of its Subsidiaries. The Commission has not issued any stop order or other order suspending the effectiveness of any registration statement filed by the Company or any of its Subsidiaries under the Exchange Act or the Securities Act. 

(k) Labor Relations. No material labor dispute exists or, to the knowledge of the Company or any of its Subsidiaries, is imminent with respect
to any of the employees of the Company or any of its Subsidiaries which would have or result in a Material Adverse Effect. 
 (l)
Compliance. Neither the Company nor any of its Subsidiaries (i) is in default under or in violation of (and no event has occurred that has not been waived that, with notice or lapse of time or both, would result in a default by the Company
or any of its Subsidiaries under), nor has the Company or any of its Subsidiaries received notice of a claim that it is in default under or that it is in violation of, any indenture, loan or credit agreement or any other agreement or instrument to
which it is a party or by which it or any of its properties is bound (whether or not such default or violation has been waived), (ii) is in violation of any order of any court, arbitrator or governmental body, or (iii) is or has been in
violation of any statute, rule or regulation of any governmental authority, including without limitation all foreign, federal, state and local laws applicable to its business, except in the case of clauses (i) and (iii) as would not have
or reasonably be expected to result in a Material Adverse Effect. 
 (m) Licenses; Compliance With FDA and Other Regulatory Requirements.

 (i) The Company and its Subsidiaries hold all material authorizations, consents, approvals, franchises, licenses and permits required
under applicable law or regulation for the operation of the business of the Company and its Subsidiaries as presently operated (the “Governmental Authorizations”). All the Governmental Authorizations have been duly issued or
obtained and are in full force and effect, and the Company and its Subsidiaries are in material compliance with the terms of all the Governmental Authorizations. The Company and its Subsidiaries have not engaged in any activity that, to their
knowledge, would cause revocation or suspension of any such Governmental Authorizations. The Company has no knowledge of any facts which would reasonably be expected to cause the Company to believe that the Governmental Authorizations will not be
renewed by the appropriate governmental authorities in the ordinary course. Neither the execution, delivery nor performance of this Agreement shall adversely affect the status of any of the Governmental Authorizations. 
 (ii) Without limiting the generality of the representations and warranties made in sub-paragraph (i) above, the Company represents and warrants that
(i) the Company and each of its Subsidiaries is in material compliance with all applicable provisions of the United States Federal Food, Drug, and Cosmetic Act and the rules and regulations promulgated thereunder (the “FDC
Act”) and equivalent laws, rules and regulations in jurisdictions outside the United States in which the Company or its Subsidiaries do business, (ii) its products and those of each of its Subsidiaries that are in the Company’s
control are not adulterated or misbranded and are in lawful distribution, (iii) all of the products marketed by and within the control of the Company 

  

 13 

 
comply in all material respects with any conditions of approval and the terms of the application by the Company to the appropriate Regulatory Authorities,
(iv) no Regulatory Authority has initiated legal action with respect to the manufacturing of the Company’s products, such as seizures or required recalls, and the Company is in compliance with applicable good manufacturing practice
regulations, (v) its products are labeled and promoted by the Company and its representatives in substantial compliance with the applicable terms of the marketing applications submitted by the Company to the Regulatory Authorities and the
provisions of the FDC Act and foreign equivalents, (vi) all adverse events that were known to and required to be reported by Company to the Regulatory Authorities have been reported to the Regulatory Authorities in a timely manner,
(vii) neither the Company nor any of its Subsidiaries is, to their knowledge, employing or utilizing the services of any individual who has been debarred under the FDC Act or foreign equivalents, (viii) all stability studies required to be
performed for products distributed by the Company or any of its Subsidiaries have been completed or are ongoing in material compliance with the applicable Regulatory Authority requirements, (ix) any products exported by the Company or any of
its Subsidiaries have been exported in compliance with the FDC Act and (x) the Company and its Subsidiaries are in compliance in all material respects with all applicable provisions of the Controlled Substances Act. For purposes of this
Section 3.1(m), “Regulatory Authority” means any governmental authority in a country or region that regulates the manufacture or sale of Company’s products, including, but not limited to, the United States Food and Drug
Administration. 
 (n) Title to Assets. The Company and the Subsidiaries do not own any real property, and have good and marketable
title to all personal property owned by them that is material to the business of the Company and the Subsidiaries, taken as a whole, in each case free and clear of all Liens, except those, if any, reflected in the Company’s financial
statements. Any real property and facilities held under lease by the Company and the Subsidiaries are held by them under valid, subsisting and enforceable leases (subject to laws of general application relating to bankruptcy, insolvency,
reorganization, moratorium or other similar laws affecting creditors’ rights generally and rules of law governing specific performance, injunctive relief, or other equitable remedies) with which the Company and the Subsidiaries are in material
compliance. 
 (o) Intellectual Property. 
 (i) The Company or a Subsidiary thereof has the right to use or is the sole and exclusive owner of all right, title and interest in and to all foreign and domestic patents, patent rights, trademarks, service marks,
trade names, brands and copyrights (whether or not registered and, if applicable, including pending applications for registration) owned, used or controlled by the Company and its Subsidiaries (collectively, the “Rights”) and in and
to each material invention, software, trade secret, technology, product, composition, formula and method of process used by the Company or its Subsidiaries (the Rights and such other items, the “Intellectual Property”), and, to the
Company’s and its Subsidiaries’ knowledge, has the right to use the same, free and clear of any claim or conflict with the rights of others; 
 (ii) other than as set forth in the SEC Reports, no material royalties or fees (license or otherwise) are payable by the Company or its Subsidiaries to any Person by reason of the ownership or use of any of the
Intellectual Property; 
  

 14 

 (iii) there have been no claims made against the Company or its Subsidiaries asserting the invalidity,
abuse, misuse, or unenforceability of any of the Intellectual Property, and, to the best of the Company’s knowledge, there are no reasonable grounds for any such claims; 
 (iv) neither the Company nor its Subsidiaries have made any claim of any violation or infringement by others of its rights in the Intellectual Property,
and to the best of the Company’s knowledge, no reasonable grounds for such claims exist; and 
 (v) neither the Company nor its
Subsidiaries have received notice that it is in conflict with or infringing upon the asserted rights of others in connection with the Intellectual Property. 
 (p) Insurance. The Company and the Subsidiaries are insured by insurers of recognized financial responsibility against such losses and risks and in such amounts as are prudent and customary in the businesses in
which the Company and the Subsidiaries are engaged. All of the insurance policies of the Company and its Subsidiaries are in full force and effect and are valid and enforceable in accordance with their terms, and the Company and its Subsidiaries
have complied with all material terms and conditions thereof. Neither the Company nor any of its Subsidiaries has any reason to believe that it will not be able to renew its existing insurance coverage as and when such coverage expires or to obtain
similar coverage from similar insurers as may be necessary to continue its business without a significant increase in cost. 
 (q)
Transactions With Affiliates and Employees. None of the officers or directors of the Company or its Subsidiaries and, to the knowledge of the Company and its Subsidiaries, none of the employees of the Company or its Subsidiaries is presently a
party to any transaction with the Company or any of its Subsidiaries (other than for services as employees, officers and directors), including any contract, agreement or other arrangement providing for the furnishing of services to or by, providing
for rental of real or personal property to or from, or otherwise requiring payments to or from any officer, director or such employee or, to the knowledge of the Company and its Subsidiaries, any entity in which any officer, director, or any such
employee has a substantial interest or is an officer, director, trustee or partner, other than (i) for payment of salary or consulting fees for services rendered, (ii) reimbursement for expenses incurred on behalf of the Company and
(iii) for other employee benefits, including stock option agreements and other stock awards under any equity compensation plan of the Company. 
 (r) Internal Accounting Controls. The Company and each of the Subsidiaries maintains a system of internal accounting controls sufficient in the judgment of the Company’s management to provide reasonable assurance that
(i) transactions are executed in accordance with management’s general or specific authorizations, (ii) transactions are recorded as necessary to permit preparation of financial statements in conformity with GAAP and to maintain asset
accountability, (iii) access to assets is permitted only in accordance with management’s general or specific authorization, and (iv) the recorded accountability for assets is compared with the existing assets at reasonable intervals
and appropriate action is taken with respect to any differences. The Company has established disclosure controls and procedures (as defined in Exchange Act Rules 13a-14 and 15d-14) for the Company and designed such disclosure controls and procedures
to ensure that material information relating to the Company, including its 

  

 15 

 
Subsidiaries, is made known to the certifying officers by others within those entities, particularly during the period in which the Company’s Form 10-K
or 10-Q, as the case may be, is being prepared. The Company’s certifying officers have evaluated the effectiveness of the Company’s controls and procedures as of September 30, 2005 (such date, the “Evaluation Date”).
The Company presented in its Form 10-Q for the quarter ended September 30, 2005, the conclusions of the certifying officers about the effectiveness of the disclosure controls and procedures based on their evaluations as of the Evaluation Date.
Since the Evaluation Date, there have not been any changes in the Company’s internal control over financial reporting that have materially affected, or are reasonably likely to materially affect, the Company’s internal control over
financial reporting. 
 (s) Certain Fees. Except for fees payable to SCO Securities LLC, no brokerage or finder’s fees or
commissions are or will be payable by the Company or its Subsidiaries to any broker, financial advisor or consultant, finder, placement agent, investment banker, bank or other Person with respect to the transactions contemplated by this Agreement.
The Purchasers shall have no obligation with respect to any fees or with respect to any claims made by or on behalf of other Persons for fees of a type contemplated in this Section that may be due in connection with the transactions contemplated by
this Agreement. 
 (t) Private Placement; Integrated Offering. Assuming the accuracy of the Purchaser’s representations and
warranties set forth in Section 3.2, no registration under the Securities Act is required for the offer and sale of the Securities by the Company to the Purchasers as contemplated hereby. The issuance and sale of the Securities hereunder does
not contravene the rules and regulations of the American Stock Exchange or any other Trading Market. Neither the Company, nor any of its Affiliates, nor any Person acting on its or their behalf has, directly or indirectly, made any offers or sales
of any security or solicited any offers to buy any security, under circumstances that would cause this offering of the Securities to be integrated with prior offerings by the Company for purposes of the Securities Act and would as a result require
registration under the Securities Act or trigger any applicable shareholder approval provisions, including, without limitation, under the rules and regulations of any exchange or automated quotation system on which any of the securities of the
Company are listed or designated. 
 (u) Charter, Bylaws and Corporate Records. The minute books of the Company and its Subsidiaries
contain in all material respects complete and accurate records of all meetings and other corporate actions of the board of directors, committees of the board of directors, incorporators and stockholders of the Company and its Subsidiaries from the
date of incorporation of each such entity to the date hereof. All material corporate decisions and actions have been validly made or taken. All corporate books, including without limitation the share transfer register, comply in all material
respects with applicable laws and regulations and have been regularly updated. 
 (v) Registration Rights. Except as set forth on
Schedule 3.1(v), no Person has any right to cause the Company to effect the registration under the Securities Act of any securities of the Company. 
  

 16 

 (w) Listing and Maintenance Requirements. Except as set forth in Schedule 3.1(w), the Company has
not, in the 12 months preceding the date hereof, received notice from any Trading Market on which the Common Stock is or has been listed or quoted to the effect that the Company is not in compliance with the listing or maintenance requirements of
such Trading Market. The Company is, and has no reason to believe that it will not in the foreseeable future continue to be, in compliance with all such listing and maintenance requirements. 
 (x) Taxes. All tax returns and tax reports required to be filed with respect to the income, operations, business or assets of the Company and its
Subsidiaries have been timely filed (or appropriate extensions have been obtained) with the appropriate governmental agencies in all jurisdictions in which such returns and reports are required to be filed, and all of the foregoing as filed are, in
all material respects, correct and complete and, in all material respects, reflect accurately all liability for taxes of the Company and its Subsidiaries for the periods to which such returns relate, and all amounts shown as owing thereon have been
paid. All income, profits, franchise, sales, use, value added, occupancy, property, excise, payroll, withholding, FICA, FUTA and other taxes (including interest and penalties), if any, collectible or payable by the Company and its Subsidiaries or
relating to or chargeable against any of its material assets, revenues or income or relating to any employee, independent contractor, creditor, stockholder or other third party through the Closing Date, were fully collected and paid by such date if
due by such date or provided for by adequate reserves in the financial statements contained in the SEC Reports as of and for the periods ended September 30, 2005 (other than taxes accruing after such date) and all similar items due through the
Closing Date will have been fully paid by that date or provided for by adequate reserves, whether or not any such taxes were reported or reflected in any tax returns or filings. No taxation authority has sought to audit the records of the Company or
any of its Subsidiaries for the purpose of verifying or disputing any tax returns, reports or related information and disclosures provided to such taxation authority, or for the Company’s or any of its Subsidiaries’ alleged failure to
provide any such tax returns, reports or related information and disclosure. No material claims or deficiencies have been asserted against or inquiries raised with the Company or any of its Subsidiaries with respect to any taxes or other
governmental charges or levies which have not been paid or otherwise satisfied, including claims that, or inquiries whether, the Company or any of its Subsidiaries has not filed a tax return that it was required to file, and, to the best of the
Company’s and its Subsidiaries’ knowledge, there exists no reasonable basis for the making of any such claims or inquiries. Neither the Company nor any of its Subsidiaries has waived any restrictions on assessment or collection of taxes or
consented to the extension of any statute of limitations relating to taxation. 
 (y) Environmental Matters. None of the
premises or any properties owned, occupied or leased by the Company or its Subsidiaries (the “Premises”) has been used by the Company or the Subsidiaries or, to the Company’s knowledge, by any other Person, to manufacture,
treat, store, or dispose of any substance that has been designated to be a “hazardous substance” under applicable Environmental Laws (hereinafter defined) (“Hazardous Substances”) in violation of any applicable
Environmental Laws. To their knowledge, the Company and its Subsidiaries have not disposed of, discharged, emitted or released any Hazardous Substances which would require, under applicable Environmental Laws, remediation, investigation or similar
response activity. No Hazardous Substances are present as a result of the actions of the Company or its Subsidiaries or, to the Company’s or its Subsidiaries’ knowledge, any other Person, in, on or under the Premises which would give rise
to any liability or clean-up 

  

 17 

 
obligations of the Company or its Subsidiaries under applicable Environmental Laws. The Company and its Subsidiaries and, to the Company’s or its
Subsidiaries knowledge, any other Person for whose conduct it may be responsible pursuant to an agreement or by operation of law, are in compliance with all laws, regulations and other federal, state or local governmental requirements, and all
applicable judgments, orders, writs, notices, decrees, permits, licenses, approvals, consents or injunctions in effect on the date of this Agreement relating to the generation, management, handling, transportation, treatment, disposal, storage,
delivery, discharge, release or emission of any Hazardous Substance (the “Environmental Laws”). Neither the Company or its Subsidiaries nor, to the Company’s or its Subsidiaries’ knowledge, any other Person for whose
conduct it may be responsible pursuant to an agreement or by operation of law has received any written complaint, notice, order, or citation of any actual, threatened or alleged noncompliance with any of the Environmental Laws, and there is no
proceeding, suit or investigation pending or, to the Company’s or its Subsidiaries’ knowledge, threatened against the Company or its Subsidiaries or, to the Company’s or its Subsidiaries’ knowledge, any such Person with respect
to any violation or alleged violation of the Environmental Laws, and, to the knowledge of the Company or its Subsidiaries, there is no basis for the institution of any such proceeding, suit or investigation. 
 (z) Disclosure. The Company confirms that neither the Company nor any other Person acting on its behalf and at the direction of the Company, has
provided any of the Purchasers or their agents or counsel with any information that in the Company’s reasonable judgment, at the time such information was furnished, constitutes material, non-public information, other than information relating
to the fact that the Company was considering and engaged in the transactions contemplated by the Transaction Documents. The Company understands and confirms that the Purchasers will rely on the foregoing representations and covenants in effecting
transactions in securities of the Company. No representation or warranty made by the Company in this Agreement or the Transaction Documents or in any schedule or exhibit furnished hereto or thereto contains any untrue statement of a material fact or
omits to state any material fact necessary in order to make the statements made therein, in light of the circumstances under which they were made, not misleading. 
 3.2 Representations and Warranties of the Purchasers. 
 Each Purchaser hereby, for itself and
for no other Purchaser, represents and warrants as of the date hereof and as of the Closing Date to the Company as follows: 
 (a)
Organization; Authority; Enforceability. Such Purchaser (other than individuals) is an entity duly organized, validly existing and in good standing under the laws of the jurisdiction of its organization with full power and authority to enter
into and to consummate the transactions contemplated by the Transaction Documents and otherwise to carry out its obligations thereunder. The execution, delivery and performance by such Purchaser of the transactions contemplated by this Agreement has
been duly authorized by all necessary corporate or similar action on the part of such Purchaser. Each Transaction Document to which it is a party has been duly executed by such Purchaser, and when delivered by such Purchaser in accordance with the
terms hereof, will constitute the valid and legally binding obligation of such Purchaser, enforceable against it in accordance with its terms, except (i) as limited by laws of general application relating to bankruptcy, insolvency,
reorganization, moratorium or other similar laws 

  

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affecting creditors’ rights generally, (ii) as limited by rules of law governing specific performance, injunctive relief, or other equitable
remedies and (iii) to the extent the indemnification provisions contained in the Transaction Documents may be limited by applicable federal or state securities laws. 
 (b) General Solicitation. Such Purchaser is not purchasing the Securities as a result of any advertisement, article, notice or other communication regarding the Securities published in any newspaper, magazine
or similar media or broadcast over television or radio or presented at any seminar or any other general solicitation or general advertisement. 
 (c) No Public Sale or Distribution. Such Purchaser is (i) acquiring the Shares and Warrants and (ii) upon exercise of the Warrants will acquire the Warrant Shares, for its own account and not with a view towards, or for
resale in connection with, the public sale or distribution thereof; provided, however, that by making the representations herein, such Purchaser does not agree to hold any of the Securities for any minimum or other specific term and reserves
the right to dispose of the Securities at any time in accordance with or pursuant to a registration statement or an exemption under the Securities Act. Such Purchaser is acquiring the Securities hereunder in the ordinary course of its business. Such
Purchaser does not have any agreement or understanding, directly or indirectly, with any Person to distribute any of the Securities. 
 (d) Accredited Investor Status. Such Purchaser is an “accredited investor” as that term is defined in Rule 501(a) of Regulation D. 
 (e) Jurisdiction of Offer. Such Purchaser is a resident of (or in the case of a corporation, trust, partnership or other legal entity, has its principal place of business in) the jurisdiction set forth
below such Purchaser’s name on Schedule 1 attached hereto. 
 (f) Reliance on Exemptions. Such Purchaser understands that
the Shares and Warrants are being offered and sold to it in reliance on specific exemptions from the registration requirements of United States federal and state securities laws and that the Company is relying in part upon the truth and accuracy of,
and such Purchaser’s compliance with, the representations, warranties, agreements, acknowledgments and understandings of such Purchaser set forth herein in order to determine the availability of such exemptions and the eligibility of such
Purchaser to acquire the Shares and Warrants. 
 (g) Information. Such Purchaser and its advisors, if any, have been furnished with
all publicly available materials relating to the business, finances and operations of the Company and such other publicly available materials relating to the offer and sale of the Shares and Warrants as have been requested by such Purchaser. Such
Purchaser and its advisors, if any, have been afforded the opportunity to ask questions of the Company. Neither such inquiries nor any other due diligence investigations conducted by such Purchaser or its advisors, if any, or its representatives
shall modify, amend or affect such Purchaser’s right to rely on the Company’s representations and warranties contained herein. Such Purchaser understands that its investment in the Shares and Warrants involves a high degree of risk.

  

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 (h) No Governmental Review. Such Purchaser understands that no United States federal or state
agency or any other government or governmental agency has passed on or made any recommendation or endorsement of the Shares and Warrants or the fairness or suitability of the investment in the Shares and Warrants, nor have such authorities passed
upon or endorsed the merits of the offering of the Shares and Warrants. 
 (i) Experience of Such Purchaser. Such Purchaser, either
alone or together with its representatives, has such knowledge, sophistication and experience in business and financial matters, including investing in companies engaged in the business in which the Company is engaged, so as to be capable of
evaluating the merits and risks of the prospective investment in the Shares and Warrants, and has so evaluated the merits and risks of such investment. Such Purchaser is able to bear the economic risk of an investment in the Shares and Warrants and,
at the present time, is able to afford a complete loss of such investment. 
 The Company acknowledges and agrees that each Purchaser does
not make or has not made any representations or warranties with respect to the transactions contemplated hereby other than those specifically set forth in this Section 3.2. 
 ARTICLE IV 
 OTHER AGREEMENTS OF THE PARTIES 
 4.1 Transfer Restrictions. 
 (a) The Securities may only be disposed of in compliance with state and federal securities laws. Each Purchaser will not, directly or indirectly, offer, sell, pledge, transfer or otherwise dispose of (or solicit any offers to buy, purchase
or otherwise acquire or take pledge of) any of the Securities except in compliance with the Securities Act, applicable state securities laws and the respective rules and regulations promulgated thereunder. In connection with any transfer of
Securities other than pursuant to an effective registration statement, to the Company, to an Affiliate of a Purchaser (who is an accredited investor and executes a customary representation letter) or in connection with a pledge as contemplated in
Section 4.1(b), the Company may require the transferor thereof to provide to the Company an opinion of counsel selected by the transferor and reasonably acceptable to the Company, the form and substance of which opinion shall be reasonably
satisfactory to the Company, to the effect that such transfer does not require registration of such transferred Securities under the Securities Act, provided, however, that in the case of a transfer pursuant to Rule 144, no opinion shall be
required if the transferor provides the Company with a customary seller’s representation letter reasonably satisfactory to the Company, and if such sale is not pursuant to subsection (k) of Rule 144, a customary broker’s
representation letter and a Form 144. Any such transferee that agrees in writing to be bound by the terms of this Agreement and the Investor Rights Agreement shall have the rights of a Purchaser under this Agreement and the Investor Rights
Agreement. Except as required by federal securities laws and the securities laws of any state or other jurisdiction within the United States and as expressly set forth in the Transaction Documents, the Securities may be transferred, in whole or in
part, by any of the Purchasers at any time. The Company shall reissue certificates evidencing the Securities upon surrender of certificates evidencing the Securities being transferred in accordance with this Section 4.1(a). 
  

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 (b) The Purchasers agree to the imprinting, so long as is required by this Section 4.1(b), of a
legend on any of the Securities in substantially the following form: 
 THESE SECURITIES HAVE NOT BEEN REGISTERED WITH THE SECURITIES AND
EXCHANGE COMMISSION OR THE SECURITIES COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY, MAY NOT BE OFFERED OR SOLD EXCEPT
PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES ACT OR PURSUANT TO AN AVAILABLE EXEMPTION FROM, OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT AND IN ACCORDANCE WITH APPLICABLE STATE
SECURITIES LAWS AS EVIDENCED BY A LEGAL OPINION OF COUNSEL TO THE TRANSFEROR TO SUCH EFFECT, THE SUBSTANCE OF WHICH SHALL BE REASONABLY ACCEPTABLE TO THE COMPANY. THESE SECURITIES MAY BE PLEDGED IN CONNECTION WITH A BONA FIDE MARGIN ACCOUNT WITH A
REGISTERED BROKER-DEALER OR OTHER LOAN WITH A FINANCIAL INSTITUTION THAT IS AN “ACCREDITED INVESTOR” AS DEFINED IN RULE 501(a) UNDER THE SECURITIES ACT. 
 The Company acknowledges and agrees that a Purchaser may from time to time pledge pursuant to a bona fide margin agreement with a registered broker-dealer or grant a security interest in some or all of the Securities,
in accordance with all applicable securities laws, to a financial institution that is an “accredited investor” as defined in Rule 501(a) under the Securities Act and, if required under the terms of such arrangement, such Purchaser may
transfer pledged or secured Securities to the pledgees or secured parties. Such a pledge or transfer would not be subject to approval of the Company and no opinion of legal counsel of the pledgee, secured party or pledgor shall be required in
connection therewith; provided, however, that such Purchaser shall provide the Company with such documentation as is reasonably requested by the Company to ensure that the pledge is pursuant to a bona fide margin agreement with a registered
broker-dealer or a security interest in some or all of the Securities to a financial institution that is an “accredited investor” as defined in Rule 501(a) under the Securities Act. The Company will execute and deliver such documentation
as a pledgee or secured party of Securities may reasonably request in connection with a pledge or transfer of the Securities, including the preparation and filing of any required prospectus supplement under Rule 424(b)(3) under the Securities Act or
other applicable provision of the Securities Act to appropriately amend the list of selling stockholders thereunder. 
 (c) Certificates
evidencing the Securities shall not contain any legend (including the legend set forth in Section 4.1(b)), (i) following any sale of such Securities pursuant to Rule 144, or (ii) if such Securities are eligible for sale under Rule
144(k), or (iii) if such legend is not required under applicable requirements of the Securities Act (including judicial interpretations and pronouncements issued by the Staff of the Commission). The Company shall use its best efforts to cause
its counsel to issue a legal opinion to the Company’s transfer agent promptly upon the occurrence of any of the events in clauses (i), (ii) or (iii) above to effect the removal of the legend hereunder and shall also use its best
efforts to cause its counsel to issue a “blanket” legal opinion to the Company’s transfer agent promptly after the Effective Date, if required by the Company’s transfer agent, to allow sales pursuant to an effective Registration
Statement. The 

  

 21 

 
Company agrees that at such time as such legend is no longer required under this Section 4.1(c), it will, no later than three Trading Days following the
delivery by a Purchaser to the Company or the Company’s transfer agent of a certificate representing Securities issued with a restrictive legend, deliver or cause to be delivered to such Purchaser a certificate representing such Securities that
is free from all restrictive and other legends. The Company may not make any notation on its records or give instructions to any transfer agent of the Company that enlarge the restrictions on transfer set forth in this Section. 
 (d) Each Purchaser, severally and not jointly, agrees that the removal of the restrictive legend from certificates representing Securities as set forth
in this Section 4.1 is predicated upon the Company’s reliance on, and the Purchaser’s agreement that, and each Purchaser hereby agrees that, the Purchaser will not sell any Securities except pursuant to either the registration
requirements of the Securities Act, including any applicable prospectus delivery requirements, or an exemption therefrom. 
 4.2
Furnishing of Information. 
 As long as any Purchaser owns Securities, the Company covenants to timely file (or obtain extensions
in respect thereof and file within the applicable grace period) all reports required to be filed by the Company after the date hereof pursuant to the Exchange Act. Upon the request in writing of any such holder of Securities, the Company shall
deliver to such holder a written certification of a duly authorized officer as to whether it has complied with the preceding sentence. As long as any Purchaser owns Securities, if the Company is not required to file reports pursuant to the Exchange
Act, it will prepare and furnish to the Purchasers and make publicly available in accordance with Rule 144(c), such information as is required for the Purchasers to sell the Securities under Rule 144. The Company further covenants that it will take
such further action as any holder of Securities may reasonably request in writing, all to the extent required from time to time to enable such Person to sell such Securities without registration under the Securities Act within the limitation of the
exemptions provided by Rule 144. 
 4.3 Integration. 
 The Company shall not sell, offer for sale or solicit offers to buy or otherwise negotiate in respect of any security (as defined in Section 2 of the
Securities Act) that would be integrated with the offer or sale of the Securities in a manner that would require the registration under the Securities Act of the sale of the Securities to the Purchasers or that would be integrated with the offer or
sale of the Securities in violation of the rules and regulations of any Trading Market. 
 4.4 Limitation on Future Financing.

 From the date hereof until the earlier of 60 calendar days after the Closing Date or 15 calendar days after the Effective Date, the
Company shall not effect an issuance of its Common Stock or Common Stock Equivalents. Notwithstanding anything to the contrary herein, this Section 4.4 shall not apply to the following: (a) the granting of options or other equity
compensation awards or the issuance of Common Stock or Common Stock Equivalents to employees, independent contractors, officers and directors of the Company pursuant to any equity compensation plan or arrangement duly adopted by a majority of the
non-employee 

  

 22 

 
members of the Board of Directors of the Company or a majority of the members of a committee of non-employee directors established for such purpose (and the
exercise of such options or Common Stock Equivalents), or (b) the exercise of any security issued by the Company in connection with the offer and sale of the Company’s securities pursuant to this Agreement, or (c) the exercise of or
conversion of any convertible securities, options or warrants issued and outstanding on the date hereof, or (d) the issuance of Common Stock or Common Stock Equivalents in connection with acquisitions, mergers, strategic investments or
transactions, partnerships, license agreements, business relationship or joint venture, the primary purpose of which is not to raise capital, or (e) the issuance of securities pursuant to a stock split or stock dividend or similar capital
modification, or (f) the issuance of securities upon the authorization of the Company’s Board of Directors in connection with business conducted by the Company with vendors, lessors or financial institutions in connection with financing
transactions. 
 4.5 Publicity. 
 The Company shall, within two Business Days following the Closing Date, file a Current Report on Form 8-K, disclosing the transactions contemplated hereby and make such other filings and notices in the manner and time
required by the Commission. The Company and SCO Securities LLC shall consult with each other in issuing any press releases with respect to the transactions contemplated hereby, and neither the Company nor any Purchaser nor SCO Securities LLC shall
issue any such press release or otherwise make any such public statement without the prior consent of the Company, with respect to any such press release of any Purchaser or SCO Securities LLC, or without the prior consent of SCO Securities LLC,
with respect to any such press release of the Company, except if such disclosure is required by law, in which case the disclosing party shall promptly provide the other party with prior notice of such public statement or communication. 

4.6 Shareholders Rights Plan. 
 No claim will be made or enforced by the Company or any other Person that (a) any Purchaser is an “acquiring person” under any shareholders rights plan or similar plan or arrangement in effect or hereafter adopted by the
Company, or (b) that any Purchaser could be deemed to trigger the provisions of any such plan or arrangement; solely, in each case, by virtue of receiving Securities under the Transaction Documents or by entering into the Transaction Documents.

 4.7 Non-Public Information. 
 The Company covenants and agrees that neither it nor any other Person acting on its behalf will provide any Purchaser or its agents or counsel with any information that the Company believes constitutes material
non-public information, unless prior thereto such Purchaser shall have executed a written agreement regarding the confidentiality and use of such information or shall have otherwise expressly agreed or undertaken to maintain the confidentiality of
such information. The Company understands and confirms that each Purchaser shall be relying on the foregoing representations in effecting transactions in securities of the Company. 
  

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 4.8 Use of Proceeds. 
 Until the date on which the Purchasers own less than 50% of the Shares issued pursuant to this Agreement, the Company covenants and agrees that the
proceeds from the sale of the Common Stock and Warrants shall be used by the Company for working capital and general corporate purposes; under no circumstances shall any portion of the proceeds be applied to: 
 (i) accelerated repayment of debt existing on the date hereof; 
 (ii) the payment of dividends or other distributions on any capital stock of the Company; 
 (iii) increased
executive compensation (other than in the ordinary course of business) or loans to officers, employees, stockholders or directors, unless approved by a majority of the disinterested members of the Board of Directors, or a majority of the members of
a committee of disinterested members of the Board of Directors established for such purpose; 
 (iv) the purchase of debt or equity
securities of any Person, including the Company and its Subsidiaries, except in each case: (a) in connection with investment of excess cash in high quality (A1/P1 or better) money market instruments having maturities of one year or less;
(b) in connection with acquisitions, mergers, strategic investments or transactions, partnerships, license agreements, joint ventures or other business relationships, in each case related to the business of the Company; and (c) pursuant to
the repurchase rights of the Company under options or restricted stock grants to, or employee arrangements with, directors, employees or consultants of the Company, in each case, granted under equity incentive plans or agreements approved by the
Board of Directors of the Company or any duly authorized committee thereof; or 
 (v) any expenditure not directly related to the business of
the Company, except in connection with acquisitions, mergers, strategic investments or transactions, partnerships, license agreements, joint ventures or other business relationships, in each case related to the business. 
 4.9 Reservation of Common Stock. 
 As of the date hereof, the Company has reserved and the Company shall continue to reserve and keep available at all times, free of preemptive rights, a sufficient number of shares of Common Stock for the purpose of enabling the Company to
issue Shares pursuant to this Agreement and Warrant Shares upon exercise of the Warrants. 
 4.10 Listing of Common Stock.

 The Company hereby agrees to use commercially reasonable efforts to maintain the listing of the Common Stock on the American Stock
Exchange or any applicable Trading Market. The Company further agrees, if the Company applies to have the Common Stock traded on any other Trading Market, it will include in such application the Shares and the Warrant Shares, and will take such
other action as is necessary to cause the Shares and Warrant Shares to be listed on such other Trading Market as promptly as possible to the extent that any of the Common Stock is listed thereon. 
  

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 4.11 Business Operations. Until the earlier of: (i) the fourth year anniversary of the
Closing Date and (ii) the date that the Purchasers own less than 50% of the Shares originally issued pursuant to this Agreement, the Company shall comply with the following covenants: 
 (a) Insurance. The Company and its Subsidiaries shall maintain insurance policies such that the representations contained in the first sentence of
Section 3.1(p) hereof continue to be true and correct and shall, from time to time upon the written request of the Purchasers, promptly furnish or cause to be furnished to the Purchasers evidence, in form and substance reasonably satisfactory
to the Purchasers, of the maintenance of all insurance maintained by it. 
 (b) Corporate Existence; Licenses. The Company shall
preserve and maintain and cause its Subsidiaries to preserve and maintain their corporate existence and good standing in the jurisdiction of their incorporation and the rights, privileges and franchises of the Company and its Subsidiaries (except,
in each case, in the event of a merger or consolidation in which the Company or its Subsidiaries, as applicable, is not the surviving entity) in each case where the failure to so preserve or maintain would have a Material Adverse Effect on the
financial condition, business or operations of the Company and its Subsidiaries taken as a whole. The Company shall, and shall cause its Subsidiaries to, maintain at all times all material licenses and permits from any governmental agency or
instrumentality thereof necessary to the conduct of its business and as required by any governmental agency or instrumentality thereof, including without limitation all FDA clearances and approvals. 
 (c) Taxes and Claims. The Company and its Subsidiaries shall duly pay and discharge (a) all taxes, assessments and governmental charges upon
or against the Company or its properties or assets prior to the date on which penalties attach thereto, unless and to the extent that such taxes are being diligently contested in good faith and by appropriate proceedings, and appropriate reserves
therefor have been established, and (b) all material lawful claims, whether for labor, materials, supplies, services or anything else which might or would, if unpaid, become a lien or charge upon the properties or assets of the Company or its
Subsidiaries, unless and to the extent only that the same are being contested in good faith and by appropriate proceedings and appropriate reserves therefor have been established. 
 (d) Affiliate Transactions. Until the date on which the Purchasers hold less than 50% of the Shares issued pursuant to this Agreement, except for
transactions approved by a majority of the disinterested members of the board of directors of the Company, or a majority of the members of a committee of disinterested directors established for such purpose, neither the Company nor any of its
Subsidiaries shall enter into any transaction with any (i) director, officer, employee or holder of more than 5% of the outstanding capital stock of any class or series of capital stock of the Company or any of its Subsidiaries,
(ii) member of the immediate family of any such person, or (iii) corporation, partnership, trust or other entity in which any such person, or member of the immediate family of any such person, is a director, officer, trustee, partner or
holder of more than 5% of the outstanding capital stock thereof. 
  

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 4.12 Securities Law Compliance. 
 (a) Securities Act. The Company shall timely prepare and file with the Securities and Exchange Commission the form of notice of the sale of
securities pursuant to the requirements of Regulation D regarding the sale of the Common Stock and Warrants under this Agreement. 
 (b)
State Securities Law Compliance — Sale. The Company shall timely prepare and file such applications, consents to service of process (but not including a general consent to service of process) and similar documents and take such other steps
and perform such further acts as shall be required by the state securities law requirements of each jurisdiction where a Purchaser resides, as indicated on Schedule 1, with respect to the sale of the Common Stock and Warrants under this
Agreement. 
 ARTICLE V 
 INDEMNIFICATION, TERMINATION AND DAMAGES 
 5.1 Survival of Representations. 
 Except as otherwise provided below in this Section 5.1, the representations and warranties of the Company and the Purchasers contained in or made
pursuant to this Agreement shall survive the execution and delivery of this Agreement and the Closing Date and shall continue in full force and effect for a period of two (2) years from the Closing Date; provided, however, that the
Company’s warranties and representations under Sections 3.1(a) (Subsidiaries), 3.1(g) (Capitalization), 3.1(x) (Taxes) and 3.1(y) (Environmental Matters) shall survive the Closing Date and continue in full force and effect until the expiration
of all applicable statutes of limitation. The Company’s and the Purchasers’ warranties and representations shall in no way be affected or diminished in any way by any investigation of (or failure to investigate) the subject matter thereof
made by or on behalf of the Company or the Purchasers. 
 5.2 Indemnification. 
 (a) The Company agrees to indemnify and hold harmless the Purchasers, their Affiliates, each of their officers, directors, employees and agents and their
respective successors and assigns, from and against any losses, damages, or expenses which are caused by or arise out of (i) any breach or default in the performance by the Company of any covenant or agreement made by the Company in this
Agreement or in any of the Transaction Documents; (ii) any breach of warranty or representation made by the Company in this Agreement or in any of the Transaction Documents; and/or (iii) any and all third party actions, suits, proceedings,
claims, demands, judgments, costs and expenses (including reasonable legal fees and expenses) incident to any of the foregoing. 
 (b) The
Purchasers, severally and not jointly, agree to indemnify and hold harmless the Company, its Affiliates, each of their officers, directors, employees and agents and their respective successors and assigns, from and against any losses, damages, or
expenses which are caused by or arise out of (A) any breach or default in the performance by the Purchasers of any covenant or agreement made by the Purchasers in this Agreement or in any of the 

  

 26 

 
Transaction Documents; (B) any breach of warranty or representation made by the Purchasers in this Agreement or in any of the Transaction Documents; and
(C) any and all third party actions, suits, proceedings, claims, demands, judgments, costs and expenses (including reasonable legal fees and expenses) incident to any of the foregoing; provided, however, that a Purchaser’s liability
under this Section 5.2(b) shall not exceed the Purchase Price paid by such Purchaser hereunder. 
 5.3 Indemnity Procedure.

 A party or parties hereto agreeing to be responsible for or to indemnify against any matter pursuant to this Agreement is referred to
herein as the “Indemnifying Party” and the other party or parties claiming indemnity is referred to as the “Indemnified Party”. An Indemnified Party under this Agreement shall, with respect to claims asserted
against such party by any third party, give written notice to the Indemnifying Party of any liability which might give rise to a claim for indemnity under this Agreement within sixty (60) Business Days of the receipt of any written claim from
any such third party, but not later than twenty (20) days prior to the date any answer or responsive pleading is due, and with respect to other matters for which the Indemnified Party may seek indemnification, give prompt written notice to the
Indemnifying Party of any liability which might give rise to a claim for indemnity; provided, however, that any failure to give such notice will not waive any rights of the Indemnified Party except to the extent the rights of the Indemnifying
Party are materially prejudiced. 
 The Indemnifying Party shall have the right, at its election, to take over the defense or settlement of
such claim by giving written notice to the Indemnified Party at least fifteen (15) days prior to the time when an answer or other responsive pleading or notice with respect thereto is required. If the Indemnifying Party makes such election, it
may conduct the defense of such claim through counsel of its choosing (subject to the Indemnified Party’s approval of such counsel, which approval shall not be unreasonably withheld), shall be solely responsible for the expenses of such defense
and shall be bound by the results of its defense or settlement of the claim. The Indemnifying Party shall not settle any such claim without prior notice to and consultation with the Indemnified Party, and no such settlement involving any equitable
relief or which might have an adverse effect on the Indemnified Party may be agreed to without the written consent of the Indemnified Party (which consent shall not be unreasonably withheld). So long as the Indemnifying Party is diligently
contesting any such claim in good faith, the Indemnified Party may pay or settle such claim only at its own expense and the Indemnifying Party will not be responsible for the fees of separate legal counsel to the Indemnified Party, unless the named
parties to any proceeding include both parties or representation of both parties by the same counsel would be inappropriate in the reasonable opinion of the Indemnified Party, due to conflicts of interest or otherwise. If the Indemnifying Party does
not make such election, or having made such election does not, in the reasonable opinion of the Indemnified Party proceed diligently to defend such claim, then the Indemnified Party may (after written notice to the Indemnifying Party), at the
expense of the Indemnifying Party, elect to take over the defense of and proceed to handle such claim in its discretion and the Indemnifying Party shall be bound by any defense or settlement that the Indemnified Party may make in good faith with
respect to such claim. In connection therewith, the Indemnifying Party will fully cooperate with the Indemnified Party should the Indemnified Party elect to take over the defense of any such claim. The parties agree to cooperate in defending such
third party claims and the Indemnified Party 

  

 27 

 
shall provide such cooperation and such access to its books, records and properties as the Indemnifying Party shall reasonably request with respect to any
matter for which indemnification is sought hereunder; and the parties hereto agree to cooperate with each other in order to ensure the proper and adequate defense thereof. 
 With regard to claims of third parties for which indemnification is payable hereunder, such indemnification shall be paid by the Indemnifying Party upon
the earlier to occur of: (i) the entry of a judgment against the Indemnified Party and the expiration of any applicable appeal period, or if earlier, five (5) days prior to the date that the judgment creditor has the right to execute the
judgment; (ii) the entry of an unappealable judgment or final appellate decision against the Indemnified Party; or (iii) a settlement of the claim. Notwithstanding the foregoing, the reasonable expenses of counsel to the Indemnified Party
shall be reimbursed on a current basis by the Indemnifying Party. With regard to other claims for which indemnification is payable hereunder, such indemnification shall be paid promptly by the Indemnifying Party upon demand by the Indemnified Party.

 ARTICLE VI 
 MISCELLANEOUS 
 6.1 Fees and Expenses. 
 The Company shall be responsible for the payment of the Purchasers’ reasonable and documented legal fees and other third-party expenses relating to
the preparation, negotiation and execution of this Agreement and the Transaction Documents and the consummation of the transactions contemplated herein, in an aggregate amount not to exceed $70,000 unless otherwise agreed in writing by the Company;
provided, that the limit set forth in this Section 6.1 shall not apply to registration fees and expenses as described in Section 4 of the Investor Rights Agreement. 
 6.2 Entire Agreement. 
 The
Transaction Documents, together with the exhibits and schedules thereto, contain the entire understanding of the parties with respect to the subject matter hereof and supersede all prior agreements and understandings, oral or written, with respect
to such matters, which the parties acknowledge have been merged into such documents, exhibits and schedules. 
 6.3 Notices.

 Any and all notices or other communications or deliveries required or permitted to be provided hereunder shall be in writing and shall
be deemed given and effective on the earliest of (a) the date of transmission, if such notice or communication is delivered via facsimile at the facsimile number specified on the signature pages attached hereto prior to 5:00 p.m. (New York City
time) on a Trading Day, (b) the next Trading Day after the date of transmission, if such notice or communication is delivered via facsimile at the facsimile number on the signature pages attached hereto on a day that is not a Trading Day or
later than 5:00 p.m. (New York City time) on any Trading Day, (c) the Trading Day following the date of mailing, if sent by U.S. nationally recognized overnight courier service, or (d) upon actual receipt by the party to whom 

  

 28 

 
such notice is required to be given. The address for such notices and communications shall be as follows: 
 If to the Purchasers, at each Purchaser’s address set forth under its name on Schedule 1 attached hereto, or with respect to the Company,
addressed to: 
 Antares Pharma, Inc. 
 707 Eagleview Blvd. 
 Suite 414 
 Exton, PA 19341 
 Attention: President 
 Facsimile No.: (610) 458 0756 
 or to such other address or addresses or facsimile number or numbers as any such party may most recently have
designated in writing to the other parties hereto by such notice. Copies of notices to the Company shall be sent to: 
 Morgan, Lewis & Bockius LLP 
 1701 Market Street 
 Philadelphia, PA 19103-2921 
 Attention: Joanne R. Soslow 
 Facsimile No.: (215) 963-5001 
 Copies of notices to any Purchaser shall be sent to the addresses, if any, listed on Schedule 1 attached hereto. 
 6.4 Amendments; Waivers. 
 No
provision of this Agreement may be waived or amended except in a written instrument signed, in the case of an amendment, by the Company and each Purchaser or, in the case of a waiver, by the party against whom enforcement of any such waiver is
sought. No waiver of any default with respect to any provision, condition or requirement of this Agreement shall be deemed to be a continuing waiver in the future or a waiver of any subsequent default or a waiver of any other provision, condition or
requirement hereof, nor shall any delay or omission of either party to exercise any right hereunder in any manner impair the exercise of any such right. 
 6.5 Construction. 
 The headings herein are for convenience only, do not constitute a part of
this Agreement and shall not be deemed to limit or affect any of the provisions hereof. The language used in this Agreement will be deemed to be the language chosen by the parties to express their mutual intent, and no rules of strict construction
will be applied against any party. 
 6.6 Successors and Assigns. 
 This Agreement shall be binding upon and inure to the benefit of the parties and their successors and permitted assigns. The Company may not assign this
Agreement or any rights or 

  

 29 

 
obligations hereunder without the prior written consent of each Purchaser. Any Purchaser may assign any or all of its rights under this Agreement to any
Person, provided such transferee agrees in writing to be bound, with respect to the transferred Securities, by the provisions hereof that apply to the Purchasers. 
 6.7 No Third-Party Beneficiaries. 
 This Agreement is intended for the benefit of the parties
hereto and their respective successors and permitted assigns and is not for the benefit of, nor may any provision hereof be enforced by, any other Person, except as otherwise set forth in Article V. 
 6.8 Governing Law. 
 All
questions concerning the construction, validity, enforcement and interpretation of the Transaction Documents shall be governed by and construed and enforced in accordance with the internal laws of the State of New York, without regard to the
principles of conflicts of law thereof. 
 6.9 Jurisdiction; Venue; Service of Process. 
 This Agreement shall be subject to the exclusive jurisdiction of the Federal District Court, Southern District of New York and if such court does not have
proper jurisdiction, the State Courts of New York County, New York. The parties to this Agreement agree that any breach of any term or condition of this Agreement shall be deemed to be a breach occurring in the State of New York by virtue of a
failure to perform an act required to be performed in the State of New York and irrevocably and expressly agree to submit to the jurisdiction of the Federal District Court, Southern District of New York and if such court does not have proper
jurisdiction, the State Courts of New York County, New York for the purpose of resolving any disputes among the parties relating to this Agreement or the transactions contemplated hereby. The parties irrevocably waive, to the fullest extent
permitted by law, any objection which they may now or hereafter have to the laying of venue of any suit, action or proceeding arising out of or relating to this Agreement, or any judgment entered by any court in respect hereof brought in New York
County, New York, and further irrevocably waive any claim that any suit, action or proceeding brought in Federal District Court, Southern District of New York and if such court does not have proper jurisdiction, the State Courts of New York County,
New York has been brought in an inconvenient forum. Each of the parties hereto consents to process being served in any such suit, action or proceeding, by mailing a copy thereof to such party at the address in effect for notices to it under this
Agreement and agrees that such service shall constitute good and sufficient service of process and notice thereof. Nothing in this Section 6.9 shall affect or limit any right to serve process in any other manner permitted by law. 
 6.10 Execution. 
 This
Agreement may be executed in two or more counterparts, all of which when taken together shall be considered one and the same agreement and shall become effective when counterparts have been signed by each party and delivered to the other party, it
being understood that both parties need not sign the same counterpart. In the event that any signature is delivered by facsimile transmission, such signature shall create a valid and binding obligation of the party executing (or on whose behalf such
signature is executed) with the same force and effect as if such facsimile signature page were an original thereof. 
  

 30 

 6.11 Severability. 
 If any provision of this Agreement is held to be invalid or unenforceable in any respect, the validity and enforceability of the remaining terms and
provisions of this Agreement shall not in any way be affected or impaired thereby and the parties will attempt to agree upon a valid and enforceable provision that is a reasonable substitute therefor, and upon so agreeing, shall incorporate such
substitute provision in this Agreement. 
 6.12 Replacement of Securities. 
 If any certificate or instrument evidencing any Securities is mutilated, lost, stolen or destroyed, the Company shall issue or cause to be issued in
exchange and substitution for and upon cancellation thereof, or in lieu of and substitution therefor, a new certificate or instrument, but only upon receipt of evidence reasonably satisfactory to the Company of such loss, theft or destruction and
customary and reasonable indemnity, if requested by the Company. 
 6.13 Remedies. 
 In addition to being entitled to exercise all rights provided herein or granted by law, including recovery of damages, each of the Purchasers and the
Company will be entitled to specific performance under the Transaction Documents. The parties agree that monetary damages may not be adequate compensation for any loss incurred by reason of any breach of obligations described in the foregoing
sentence and hereby agrees to waive in any action for specific performance of any such obligation the defense that a remedy at law would be adequate. 
 6.14 Payment Set Aside. 
 To the extent that the Company makes a payment or payments to any
Purchaser pursuant to any Transaction Document or a Purchaser enforces or exercises its rights thereunder, and such payment or payments or the proceeds of such enforcement or exercise or any part thereof are subsequently invalidated, declared to be
fraudulent or preferential, set aside, recovered from, disgorged by or are required to be refunded, repaid or otherwise restored to the Company, a trustee, receiver or any other person under any law (including, without limitation, any bankruptcy
law, state or federal law, common law or equitable cause of action), then to the extent of any such restoration the obligation or part thereof originally intended to be satisfied shall, to the extent permissible under applicable law, be revived and
continued in full force and effect as if such payment had not been made or such enforcement or setoff had not occurred. 
 6.15
Independent Nature of Purchasers’ Obligations and Rights. 
 The obligations of each Purchaser under any Transaction Document
are several and not joint with the obligations of any other Purchaser, and no Purchaser shall be responsible in any way for the performance of the obligations of any other Purchaser under any Transaction Document. Nothing contained herein or in any
Transaction Document, and no action taken by any Purchaser pursuant thereto, shall be deemed to constitute the Purchasers as a partnership, an 

  

 31 

 
association, a joint venture or any other kind of entity, or create a presumption that the Purchasers are in any way acting in concert or as a group with
respect to such obligations or the transactions contemplated by the Transaction Document. Each Purchaser shall be entitled to independently protect and enforce its rights, including without limitation, the rights arising out of this Agreement or out
of the other Transaction Documents, and it shall not be necessary for any other Purchaser to be joined as an additional party in any proceeding for such purpose. Each Purchaser has been represented by its own separate legal counsel in their review
and negotiation of the Transaction Documents. For reasons of administrative convenience only, Purchasers and their respective counsel have chosen to communicate with the Company through Wiggin and Dana LLP, but such counsel does not represent any of
the Purchasers in this transaction other than SCO Securities LLC. The Company has elected to provide all Purchasers with the same terms and Transaction Documents for the convenience of the Company and not because it was required or requested to do
so by the Purchasers. 
 6.16 Waiver of Trial by Jury. 
 THE PARTIES HERETO IRREVOCABLY WAIVE TRIAL BY JURY IN ANY SUIT, ACTION OR PROCEEDING RELATING TO THIS AGREEMENT OR THE TRANSACTIONS CONTEMPLATED HEREBY.

 6.17 Further Assurances. 
 Each party agrees to cooperate fully with the other parties and to execute such further instruments, documents and agreements and to give such further written assurances as may be reasonably requested by any other
party to better evidence and reflect the transactions described herein and contemplated hereby and to carry into effect the intents and purposes of this Agreement, and further agrees to take promptly, or cause to be taken, all actions, and to do
promptly, or cause to be done, all things necessary, proper or advisable under applicable law to consummate and make effective the transactions contemplated hereby, to obtain all necessary waivers, consents and approvals, to effect all necessary
registrations and filings, and to remove any injunctions or other impediments or delays, legal or otherwise, in order to consummate and make effective the transactions contemplated by this Agreement for the purpose of securing to the parties hereto
the benefits contemplated by this Agreement. 
 [Signature Page Follows] 
  

 32 

 IN WITNESS WHEREOF, the parties hereto have executed this Common Stock and Warrant Purchase Agreement as of the date
first above written. 
  

			
	COMPANY:
	
	ANTARES PHARMA, INC.
		
	By:	 	  

	Name:	 	
	Title:	 	

  

 33 

 PURCHASERS: 
  

			
	Print Exact Name:	 	  

  

			
	By:	 	  

		
	Name:	 	
		
	Title:	 	

  

			
		
	Address:	 	  

	
	  

	
	  

		
	Telephone:	 	  

		
	Facsimile:	 	  

		
	Email:	 	  

		
	SSN/EIN:	 	  

  

			
	Amount of Investment:$	 	  

 [Omnibus Antares Pharma, Inc. Common Stock and Warrant Purchase Agreement Signature Page] 
  

 34 

 Schedule 1 
 to Common Stock and Warrant Purchase Agreement 
 Purchasers and Shares of Common Stock and Warrants

  

										
	 Name, Address and Fax Number of Purchaser
	  	 Copies of Notices to
	  	Shares of
Common Stock
Purchased	  	Common Stock
Underlying
Warrants	  	Purchase
Price
	 Anthony B. Fair
 2882 Cypress Lake Road
 Statesboro, GA 30458
 Telephone: (912) 489-8606
 Fax: (912)764-8282
	  		  	40,000	  	30,000	  	$	50,000
	 Atlas Master Fund, Ltd
 Scott Schroeder, Authorized
Signatory
 c/o Balasny Asset Management
 650 Madison Avenue,
19th Floor
 New York, NY
10022
 Telephone: (212) 808-2310
 Fax:
(212) 588-1130
 e-mail: asilberstem@bam-us.con
	  		  	135,784	  	101,838	  	$	169,730
	 Bedrock Capital LP
 James Smith, Manager
 P.O. Box 1320
 St. Thomas, US Virgin Islands 00804
 Telephone: (340) 715-5555
 Fax: (340) 715-5554
 e-mail: jimsmyth@bloomberg.net
	  		  	190,000	  	142,500	  	$	237,500

  

 35 

										
	 Name, Address and Fax Number of Purchaser
	  	 Copies of Notices to
	  	Shares of
Common Stock
Purchased	  	Common Stock
Underlying
Warrants	  	Purchase
Price
	 Bristol Investment Fund, Ltd.
 c/o Bristol Capital
Advisors, LLC
 10990 Wilshire Boulevard, Suite 1410
 Los Angeles,
California 90024
 Attention: Amy Wang, Esq.
 Telephone: (310)
696-0333
 Fax: (310) 696-0334
 e-mail:
pkessler@bristolcompanies.net
 amy@bristolcompanies.net
	  		  	400,000	  	300,000	  	$	500,000
	 Christopher A. Basta
 18 Peppermill Lane
 Dix Hills, NY 11746
 Telephone: (212) 703-6064
 Fax: (212) 703-6153
 e-mail: cbasta1@bloomberg.net
	  		  	30,000	  	22,500	  	$	37,500
	 Cranshire Capital, LP
 Lawrence A. Prosser,
CFO
 666 Dundee Road, Suite 1901
 Northowok, IL 60062

Telephone: (847) 562-9030
 Fax: (847) 562-9031
 e-mail: mkopin@cranshirecapital.com
	  		  	160,000	  	120,000	  	$	200,000

  

 36 

										
	 Name, Address and Fax Number of Purchaser
	  	 Copies of Notices to
	  	Shares of
Common Stock
Purchased	  	Common Stock
Underlying
Warrants	  	Purchase
Price
	 Crescent International Ltd.
 Maxi Brezzi, Authorized
Signatory
 c/o Cantara (Switzerland) S.A
 84 Avenue Louis
Cascu
 CH.1216 Cointrin/Geneva Switzerland
 Telephone: +41 22 791
7256
 Fax: +41 22 791 7171
 e-mail:
info@cantara.dmitrust.com
	  		  	240,000	  	180,000	  	$	300,000
	 Davis B. Fox and Jill Spitzer-Fox
 1620 E. Prospect
Street
 Seattle, WA 98112
 Telephone:
(206) 322-7282
 e-mail: davisbfox39@msn.com
	  		  	40,000	  	30,000	  	$	50,000
	 Dennis Carleton and Margaret Carleton
 25 Pineybranch
Road
 Cranbury, NJ 08512
 Telephone:
(609) 448-1521
	  		  	20,000	  	15,000	  	$	25,000
	 Gregory C. Lowney & Maryanne K. Snyder
 15207 NE 68th Street
 Redmond, WA 98052
 Telephone: (425) 882-1629
 Fax:
(425) 885-2907
 email: mksnyder@aol.com
 gclowney@aol.com
	  		  	60,000	  	45,000	  	$	75,000

  

 37 

										
	 Name, Address and Fax Number of Purchaser
	  	 Copies of Notices to
	  	Shares of
Common Stock
Purchased	  	Common Stock
Underlying
Warrants	  	Purchase
Price
	 Gregory P. Kusnick and Karen Gustafson-Kusnick
 715 Second Avenue Unit 1904
 Seattle, WA 98104
 Telephone: (266) 322-4048
 Fax: (266) 322-4514
 e-mail: kusnick@cognomen.com & Gustafson@cognomen.com
	  		  	60,000	  	45,000	  	$	75,000
	 Harborview Master Fund LP
 Harbour House, 2nd Floor
 Waterfront Drive, Road
Town
 Tortola, British Virgin Islands
 Telephone:
(284) 494-4770
 Fax: (284) 494-4771
 e-mail:
junno@beaconsecurities.com
	  		  	60,000	  	45,000	  	$	75,000
	 Hudson Bay Fund, LP
 120 Broadway, 40th Floor
 New York, NY
10271
 Telephone: (212) 571-1244
 Fax:
(212) 571-1279
 Contact: Yoav Roth
 e-mail:
yroth@hudsonbaycapital.com
	  		  	600,000	  	450,000	  	$	750,000
	 Iroquois Master Fund Ltd.
 641 Lexington Avenue,
26th Floor
 New York, NY
10022
 Telephone: (212) 974-3070
 Fax:
(212) 207-3452
 Contact: Joshua Silverman
	  		  	280,000	  	210,000	  	$	350,000

  

 38 

										
	 Name, Address and Fax Number of Purchaser
	  	 Copies of Notices to
	  	Shares of
Common Stock
Purchased	  	Common Stock
Underlying
Warrants	  	Purchase
Price
	 James Karanfilian
 235 South Dwight Place
 Englewood, N.J. 07631
 Telephone: 201-567-4163
	  		  	10,000	  	7,500	  	$	12,500
	 Jay R. Solan
 15 Mohawk Drive
 Livingston, New Jersey 07039
 Telephone: (973) 992-7734
 Fax: (973) 992-7734
 e-mail: jaysloan245@aol.com
	  		  	20,000	  	15,000	  	$	25,000
	 John Curley
 58 Valley View Avenue
 Summit, NJ 07901
 Telephone: (908) 277-4213
 Fax: (908) 277-7608
 e-mail: Jaccurley@com.net
	  		  	40,000	  	30,000	  	$	50,000
	 John Peter Christensen
 Casa Del Lago
 2900 North Flagler Drive
 West Palm Beach, FL 33407
 Telephone: (561) 655-1060
 Fax: (561) 655-1060
 e-mail: ri6Johnkahuna@adelphia.net
	  		  	40,000	  	30,000	  	$	50,000
	 KMF Partners
 Karen Fleiss
 1970 Avenue of the Americas
 17th Floor
 New York, NY 10020
 Telephone: (212) 332-2496
 Fax: (212) 332-2030
 e-mail: maureen@kmfpartners.com
	  		  	120,000	  	90,000	  	$	150,000

  

 39 

									
	 Name, Address and Fax Number of Purchaser
	  	 Copies of Notices to
	  	Shares of
Common Stock
Purchased	  	Common Stock
Underlying
Warrants	  	Purchase
Price
	 Kendu Partners Company
 Michael W. Engman, General
Partner
 220 Bush Street, Suite 660
 San Franscisco, CA
94104
 Telephone: (415) 293-3818
 Fax: (415) 781-4641

e-mail: mike.engman@fimat.com
	  		  	80,000	  	60,000	  	$100,000
	 MDNH Partners LP
 Herb Kurlan, Managing
Partner
 220 Bush Street, Suite 650
 San Francisco, CA
94104
 Telephone: (415) 387-1995
 Fax:
(415) 781-8344
 e-mail: herb.kurlan@mdnhpartners.com
	  		  	40,000	  	30,000	  	$50,000
	 Midsouth Investors Fund LP
 1776 Peachtree Street
NW
 Suite 412 North
 Atlanta, GA 30309
 Telephone: (615) 254-0992
 Fax: (615) 254-1603
 Contact: Lyman O. Heidtke
	  		  	100,000	  	75,000	  	$125,000
	 Monarch Capital Fund Ltd.
 Harbout House, 2nd Floor
 Waterfront Drive, Road
Town
 Tortola, British Virgin Islands
 Telephone: (284) 494
4770
 Fax: (284) 494 4771
 e-mail:
jouno@beaconsewrities.com
	  		  	80,000	  	60,000	  	$100,000

  

 40 

										
	 Name, Address and Fax Number of Purchaser
	  	 Copies of Notices to
	  	Shares of
Common Stock
Purchased	  	Common Stock
Underlying
Warrants	  	Purchase
Price
	 Nathan Sugarman
 205 Harding Drive
 South Orange, N.J. 07079
 (973) 763-1040
 e-mail: zifelm@aol
	  		  	60,000	  	45,000	  	$	75,000
	 Nite Capital LP
 Keith A Goodman, Manager of the General
Partner
 100 East Cook Avenue, Ste 201
 Libertyville, IL
60048
 Telephone: (847) 968-7658
 Fax:
(847) 968-7658
 e-mail: keith@nitecapital.com
	  		  	240,000	  	180,000	  	$	300,000
	 Nu Vision Holdings
 1010 Northern Blvd. Ste.
208
 Great Neck, N.Y. 11021
 Telephone:
(516) 466-7844
 Fax: (516) 466-7304
 e-mail:
Steve.Kevorkian@Verizon.net
	  		  	175,000	  	131,250	  	$	218,750
	 Perceptive Life Sciences Master Fund, Ltd.
 7284 W.
Palmetto Park Road, Suite 306
 Boca Raton, FL 33433
 Telephone:
(561) 391-7770
 Fax: (561) 391-7776
 contact: Andrew C.
Sankin
 e-mail: sankin@perceptivelife.com
	  		  	800,000	  	600,000	  	$	1,000,000

  

 41 

										
	 Name, Address and Fax Number of Purchaser
	  	 Copies of Notices to
	  	Shares of
Common Stock
Purchased	  	Common Stock
Underlying
Warrants	  	Purchase
Price
	 Peter H. Weiss
 8000 SE 22nd Street
 Mercer Island, WA
98040
 Telephone: (206) 365-0014
 Fax: (413) 691-2134

e-mail: pweiss78@alumni.princeton.edu
	  		  	30,000	  	22,500	  	$	37,500
	 RAQ, LLC
 c/o Paramount Biocapital Investments
LLC
 787 Seventh Avenue, 48th Floor
 New York, NY 10019
 Telephone:
(212) 554-4345
 Fax: (212) 554-4355
 Contact: Lindsay
A. Rosenwald M.D.
 e-mails: svacamboli@paramountbio.com; mahill@paramountbio.com
	  		  	260,000	  	195,000	  	$	325,000
	 Robert O’Mara
 8 Youngs Road
 Basking Ridge, N.J. 07920
 Telephone: (973) 538-6370
	  		  	160,000	  	120,000	  	$	200,000
	 Roland E. Wheeler
 4160 W. Eaglesode
 Wenataile, WA 98801
 Telephone: (509) 670-9068
 Fax: (509) 667-8058
 e-mail: swheeler@oasismedarow.com
	  		  	60,000	  	45,000	  	$	75,000

  

 42 

										
	 Name, Address and Fax Number of Purchaser
	  	 Copies of Notices to
	  	Shares of
Common Stock
Purchased	  	Common Stock
Underlying
Warrants	  	Purchase
Price
	 Rubicon Global Value Fund, L.P
 One SW Columbia St.,
Suite 850
 Portland, Oregon 97258
 Telephone: (503)
548-4800
 Fax: (503) 548-4805
 e-mail:
steve@rubiconglobalholdings.com
	  		  	50,000	  	37,500	  	$	62,500
	 Samax Family Limited Partnership
 413 N. Queens
Avenue
 Massapequa, N. Y 11758
 Telephone:
(516) 287-5050
 Fax: (516) 223-1448
 e-mail:
drm1313@optonline.net & amargvlies@alliedmedical.org
	  		  	30,000	  	22,500	  	$	37,500
	 Sanford Gaffe and Ethel Gaffe
 6876 Adriano
Drive
 Boynton Beach, Fl 33437
 Telephone:
(561) 733-5844
 e-mail: sangat@bellsouth.net
	  		  	40,000	  	30,000	  	$	50,000
	 SDS Capital Group SPC, Ltd.
 c/o SDS Management,
LLC
 53 Old Forest Avenue, 2nd Floor
 Old Greenwich, CT 06870
 Telephone:
(203) 967-5850
 Fax: (203) 967-5851
 Contact: Steve
Derby, Director
	  		  	1,600,000	  	1,200,000	  	$	2,000,000

  

 43 

										
	 Name, Address and Fax Number of Purchaser
	  	 Copies of Notices to
	  	Shares of
Common Stock
Purchased	  	Common Stock
Underlying
Warrants	  	Purchase
Price
	 Steven M. Sack
 1795 Harvard Avenue
 Merrick, N.Y. 11566
 Telephone: (516) 377-3940
 Fax: (516) 623-9115
 e-mail: StevenSack54@hotmail.com
	  		  	115,000	  	86,250	  	$	143,750
	 Steven Mitchell Sack PSP
 Steven Mitchell Sack,
Trustee
 U/A Dated 1/1/94
 PBO Steven Mitchell Sack
 #4000-6635
 1795 Harvard Avenue
 Merrick, NY 11566
 Telephone: (516) 377-3940
 Fax: (516) 623-9115
 stevensack54@hotmail.com
	  		  	480,000	  	360,000	  	$	600,000
	 T2, Ltd.
 James Smith, Manager
 25 Highland Park Village
 STE 100-382
 Dallas, TX 75205
 Telephone: (214) 461-7256
 Fax: (214) 461-7257
 e-mail: jimsmyth@bloomberg.net
	  		  	160,000	  	120,000	  	$	200,000

  

 44 

										
	 Name, Address and Fax Number of Purchaser
	  	 Copies of Notices to
	  	Shares of
Common Stock
Purchased	  	Common Stock
Underlying
Warrants	  	Purchase
Price
	 TCMP3 Partners
 Walter Schenker, Principal
 c/o Titan Capital Management
 7 Century Drive, Suite 201
 Parsippany, NJ 07054
 Telephone: (973) 829-1335
 Fax: (973) 540-0702
 e-mail: wschenker@titancap.org
	  		  	80,000	  	60,000	  	$	100,000
	 Trust U/W Renee Weiss
 Peter H. Weiss, Trustee

P.O. Box 1682
 Mercer Island, WA 98040
 Telephone: (206) 365-0014
 Fax: (413) 691-2134
 e-mail: pweiss78@alumni.princeton.edu
	  		  	60,000	  	45,000	  	$	75,000
	 Valesco Healthcare Overseas Fund, Ltd.
 787 Seventh
Avenue, 48th Floor
 New York, NY 10019
 Telephone:
(212) 554-4307
 Fax: (212) 554-4361
 Contact: I. Keith
Maher
 e-mail: kmaher@valescocapital.com
	  		  	101,400	  	76,050	  	$	126,750

  

 45 

										
	 Name, Address and Fax Number of Purchaser
	  	 Copies of Notices to
	  	Shares of
Common Stock
Purchased	  	Common Stock
Underlying
Warrants	  	Purchase
Price
	 Valesco Healthcare Partners II L.P.
 787 Seventh Avenue,
48th Floor
 New York, NY 10019
 Telephone: (212)
554-4307
 Fax: (212) 554-4361
 Contact: I. Keith Maher

e-mail: kmaher@valescocapital.com
	  		  	98,800	  	74,100	  	$	123,500
	 Valesco Healthcare Partners I L.P.
 787 Seventh Avenue,
48th Floor
 New York, NY 10019
 Telephone:
(212) 554-4307
 Fax: (212) 554-4361
 Contact: I. Keith
Maher
 e-mail: kmaher@valescocapital.com
	  		  	59,800	  	44,850	  	$	74,750
	 Visium Balanced Fund, LP
 Mark Gottlieb, Authorized
Signatory
 650 Madison Avenue, 19th Floor
 New York, NY
10022
 Telephone: (212) 808-2300
 e-mail:
mgottlieb@bam-us.com
	  		  	280,516	  	210,387	  	$	350,645
	 Visium Balanced Offshore Fund, LTD
 Mark Gottlieb,
Authorized Signatory
 650 Madison Avenue, 19th Floor
 New York,
NY 10022
 Telephone: (212) 808-2300
 e-mail:
mgottlieb@bam-us.com
	  		  	309,960	  	232,470	  	$	387,450

  

 46 

										
	 Name, Address and Fax Number of Purchaser
	  	 Copies of Notices to
	  	Shares of
Common Stock
Purchased	  	Common Stock
Underlying
Warrants	  	Purchase
Price
	 Visium Long Bias Fund, LP
 Mark Gottlieb,
Signatory
 650 Madison Avenue, 19th floor
 New York, NY
10022
 Telephone: (212) 808-2300
 e-mail:
mgottlieb@bam-us.com
	  		  	42,904	  	32,178	  	$	53,630
	 Visium Long Bias Offshore Fund, LTD
 Mark Gottlieb,
Signatory
 650 Madison Avenue, 19th Floor
 New York, NY
10022
 Telephone: (212) 808-2300
 e-mail:
mgottlieb@bam-us.com
	  		  	230,836	  	173,127	  	$	288,545
	 Whalehaven Capital Fund Limited
 14 Par-La-Ville Road,
3rd Floor
 P.O. Box HM1027
 Hamilton HMDX Bermuda
 Telephone: (441) 295-8313
 Fax: (441) 295-5262
 Contact: Evan Schemenauer
 e-mail: evan@whalehavencapital.com
	  		  	400,000	  	300,000	  	$	500,000
	 Totals:
	  		  	8,770,000	  	6,577,500	  	$	10,962,500

  

 47 

									
	 Name, Address and Fax Number of Purchaser
	  	 Copies of Notices to
	  	Shares of
Common Stock
Purchased	  	Common Stock
Underlying
Warrants	  	Purchase
Price
	Placement Agent Warrants	  		  		  		  	
	 SCO Securities LLC
 1285 Avenue of the Americas, 35th
Floor
 New York, NY 10019
 Jeffrey B. Davis
 T: (212) 554-4158
 F: (212) 554-4058Email:
JDavis@SCOGroup.com
	  	 Michael Grundei, Esq.
 Wiggin & Dana LLP

400 Atlantic Street
 Stamford, CT 06901
 Tel: 203-363-7630
 Fax: 203-363-7676
 Email: mgrundei@wiggin.com
	  	0	  	318,000	  	0
	 Lake End Capital LLC
 33 Tall Oaks Drive
 Summit, NJ 07901
 Telephone: (212) 554-4158
 Fax: (212) 554-4058
 Contact: Jeffrey B. Davis
 e-mail: jdavis@scogroup.com
	  		  	0	  	106,000	  	0
	 Mark Alvino
 c/o SCO Securities LLC
 1285 Avenue of the Americas, 35th Floor
 New York, NY 10019
 Telephone: (212) 554-4235
 Fax: (212) 554-4058
	  		  	0	  	53,000	  	0
	 Howard Fischer
 SCO Securities LLC
 1285 Avenue of the Americas, 35th Floor
 New York, NY 10019
 Telephone: (212) 554-4235
 Fax: (212) 554-4058
	  		  	0	  	53,000	  	0
	 Dawson James Securities
 925 South Federal
Highway
 6th
Floor
 Boca Raton, FL 33432
 Attn: Robert D. Keyser,
Jr.
	  		  	0	  	347,000	  	0

  

 48

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