Document:

EX-10.3

 Exhibit 10.3 

OFFICE LEASE 
 by and
between 
 Diamond Marina LLC, a California limited liability company, 

and Diamond Marina II LLC, a California limited liability 

company 
 as Landlord

 and 
 Allergen
Research Corporation, a Delaware Corporation, as Tenant 
 8000 Marina Boulevard 

Brisbane, California 94065 

February 23, 2015 

 OFFICE LEASE 

THIS LEASE is entered into as of February 23, 2015 (the “Effective Date”) by and between DIAMOND MARINA LLC, a
California limited liability company, and DIAMOND MARINA II LLC, a California limited liability company (collectively “Landlord”), and Allergen Research Corporation, a Delaware Corporation (“Tenant”).

 1. BASIC LEASE INFORMATION. The following is a summary of basic lease information. Each item in this Article 1 incorporates all of
the terms set forth in this Lease pertaining to such item and to the extent there is any conflict between the provisions of this Article 1 and any other provisions of this Lease, the other provisions shall control. Any capitalized term not defined
in this Lease shall have the meaning set forth in the Glossary that appears at the end of this Lease. 
  

			
	Building:		8000 Marina Boulevard
			Brisbane, California 94005
		
	Premises and Rentable Area:		Suite 300, located on a portion of the Third Floor of the Building, consisting of approximately 11,665 square feet of Rentable Area. A Floor Plan of the Premises is included with this Lease and attached hereto as “Exhibit
A”.
		
	Term:		The Term is Fifty-One (51) Months, or as extended under Tenant’s Renewal Option (Section 4.4)
		
	Scheduled Date for Delivery of the Premises:		May 1, 2015.
		
	Commencement Date:		The Lease shall commence upon the later of (i) Landlord’s substantial completion of the Tenant Improvement Work and delivery of the Premises to Tenant {which date must be a Business Day), or ii) the Scheduled Date for Delivery
of the Premises.
		
	Expiration Date:		The Expiration Date is the last day of the Term, or as extended under Tenant’s Renewal Option (Section 4.4).
		
	Tenant Improvements:		Pursuant to Section 9.1, Landlord at Landlord’s expense shall perform “Tenant Improvement Work” pursuant to the terms of the “Work Letter” attached hereto as Exhibit E.

			
	Base Rent Rate Schedule:	  	The Rent Commencement Date is the Commencement Date, and the Base Rent shall be paid by Tenant based on the following schedule:

  

									
	 Period
	  	Monthly Base
Rent Rate	 	  	Monthly Base
Rent	 
	 Months 1-12
	  	$	3.25	  	  	$	37,911	  
	 Months 13-24
	  	$	3.35	  	  	$	39,078	  
	 Months 25-36
	  	$	3.45	  	  	$	40,244	  
	 Months 37-48
	  	$	3.55	  	  	$	41,411	  
	 Months 49-51
	  	$	3.66	  	  	$	42,694	  

  

			
	Abated Rent:	  	The first three (3) months of Base Rent shall be fully abated.
		
	Tenant’s Pro Rata Share:	  	The Premises contains approximately 5.8% of the Rentable Area of the Building.
		
	Base Year:	  	Calendar Year 2015
		
	Security Deposit:	  	$85,388
		
	Parking:	  	That number of parking spaces available for Tenant’s use is determined by multiplying Tenant’s Pro Rata Share by the total number of parking spaces then available upon the Property available on an unassigned and unreserved
basis, which is thirty-eight (38) parking spaces as of the Effective Date. That number shall not be reduced unless it is by a pro rata amount affecting all tenants proportionately.
		
	Use:	  	General office and administrative uses consistent with Class A office buildings.
		
	Normal Business Hours:	  	7:00 a.m. to 6:00 p.m. on each Business Day.
		
	Addresses for Notice:	  	
		
	 Landlord:
	  	Diamond Marina LLC & Diamond Marina II LLC
		  	2000 Sierra Point Parkway, Suite 100
		  	Brisbane, CA 94005
		  	Attention: Stephen P. Diamond

			
		
	 with a copy to:
		Kent Mitchell, Esq.
			Law Office of Mitchell Herzog
			550 Hamilton Avenue, Suite 230
			Palo Alto, CA 94301
		
	 Tenant:
		On and after the Commencement Date, notices shall be sent to Tenant at the Premises. Prior to the Commencement Date, notices shall be sent to Tenant at the following address:
		
			Allergen Research Corporation
			2000 Alameda de las Pulgas, Suite 161
			San Mateo, CA 94403
		
			Attention: Howard Raff
		
	Brokers:		Newmark Cornish & Carey (Landlord’s Broker)
		
			CBRE (Tenant’s Broker)
	
	Rent (defined in Section 5.2) is payable to the order of Landlord at the following address:
		
			2000 Sierra Point Parkway, Suite 100
			Brisbane, CA 94005
		
			Or wire funds to:
			[***]
			ABA Routing #: [***]
			Account #: [***]
			Credit: [***]

 2. PREMISES 

2.1. Premises. Landlord hereby leases to Tenant and Tenant hereby leases from Landlord for Tenant’s own use in the conduct of
Tenant’s business and not for purposes of speculating in real estate, for the Term and upon the terms and subject to the conditions of this Lease, that certain interior space described in Article 1 as the “Premises”,
reserving and excepting to Landlord (a) such access as may be required (including but not limited to elevator access) by Landlord to the Building roof and heating, ventilating, air conditioning, ducting, cabling systems, and other
Building Systems, (b) the right to place additional vertical penetrations in the Premises as needed for heating, ventilating, air conditioning, ducting, cabling, and other Building Systems, and (c) the right to access the Premises for the
management of the Property and fulfillment of Landlord’s duties and obligations under this Lease. Tenant’s lease of the Premises, together with the appurtenant right to use the Common Areas as described in Paragraph 2.2 below, shall be
conditioned upon and be subject to the continuing compliance by Tenant with (i) all the terms and conditions of this Lease, (ii) all Applicable Laws governing the use of the Premises and the Property, (iii) all private restrictions,
easements and other matters now of public record respecting the use of the Premises and Property, and (iv) all reasonable rules and regulations from time to time established by Landlord. The building in which the Premises is located is
sometimes referred to herein as the “Building”. 
 2.2. Common Area. Landlord hereby grants to Tenant and its
employees, agents, contractors and invitees (collectively, “Tenant’s Agents”) a non-exclusive license to use the public areas, sidewalks, driveways, parking areas and other public amenities (the “Common
Area”) associated with the Premises during the Term. Together, the Premises, the Building and the Common Area are sometimes referred to in this Lease as the “Property.” Tenant’s rights to the Common Area
shall be subject to the Rules and Regulations described in Section 23.1 and to Landlord’s reserved rights described in Article 16. 

2.3. Parking. Throughout the Term of this Lease, and any extensions thereof, Tenant shall have the right to use the number of parking
spaces specified in Article 1, at no additional cost to Tenant. Tenant’s license shall not be assigned, sublet or otherwise transferred separately from the Premises. Tenant agrees that neither Tenant nor Tenant’s Agents shall use parking
spaces in excess of the number of spaces allocated to Tenant or in areas designated for other uses. Landlord shall have the right, at Landlord’s sole discretion, to specifically designate the location of Tenant’s parking spaces within the
parking areas of the Common Area, and Tenant’s designated parking spaces (if any) may be relocated by Landlord from time to time upon written notice. Tenant shall not at any time park, or permit the parking of the trucks or vehicles of Tenant
or Tenant’s Agents in any portion of the Common Area not designated by Landlord for such use by Tenant. Tenant shall not park nor permit to be parked any inoperative vehicles or store any materials or equipment on any portion of the parking
area or other areas of the Common Area. Tenant agrees to assume responsibility for compliance by Tenant’s Agents with the parking provisions contained in this Section. Tenant hereby authorizes Landlord at Tenant’s expense to attach
violation stickers or notices to such vehicles not parked in compliance with this Section and to tow away any such vehicles. In addition, Landlord may set a specific section of the parking area aside for visitor or specially assigned parking for the
Property. 
 2.4. Fitness Center. Tenant’s employees may use the existing fitness center facilities located in 2000 Sierra Point
Parkway (“Fitness Center”) on a non-exclusive basis at no charge during the Term, subject to the Rules and Regulations, so long as Landlord operates the Fitness Center as part of the Common Area. 

  
 4 

 2.5. Conference Center. Subject to Landlord’s reserved rights described in Article
16, Tenant may utilize the Conference Center in 2000 Sierra Point Parkway subject to the Rules and Regulations for Landlord’s standard charge, so long as Landlord operates the Conference Center as part of the Common Area. 

3. ACCEPTANCE 
 Except
for the Tenant Improvement Work pursuant to Section 9.1 and Exhibit E, Tenant accepts the Premises as furnished by Landlord, which consist of the improvements as they exist as of the Effective Date in their existing “as-is” condition,
and Landlord shall have no obligation for construction work or improvements on or to the Premises, the Building or the Common Area. Prior to entering into this Lease, Tenant has made a thorough and independent examination of the Property and all
matters related to Tenant’s decision to enter into this Lease. Tenant is thoroughly familiar with all aspects of the Property and is satisfied that it is in an acceptable condition and meet Tenant’s needs. Tenant does not rely on, and
Landlord does not make, any express or implied representations or warranties as to any matters including, without limitation, (a) the physical condition of the Property, the Building Structure, or the Building Systems, (including, without
limitation, indoor air quality), (b) the existence, quality, adequacy or availability of utilities serving the Property, (c) the use, habitability, merchantability, fitness or suitability of the Premises for Tenant’s intended use, {d)
the likelihood of deriving business from Tenant’s location or the economic feasibility of Tenant’s business, (e) Hazardous Materials in the Premises, or on, in under or around the Property, (f) zoning, entitlements or any laws,
ordinances or regulations which may apply to Tenant’s use of the Premises or business operations, or (g) any other matter. Tenant has satisfied itself as to such suitability and other pertinent matters by Tenant’s own inquiries and
tests into all matters relevant in determining whether to enter into this Lease. Tenant shall, by entering into and occupying the Premises, be deemed to have accepted the Premises and to have acknowledged that the same are in good order, condition
and repair. Upon the Commencement Date, Tenant shall execute and deliver to Landlord the Acceptance Form attached hereto as Exhibit D. 

4. TERM 
 4.1.
Term. The Premises are leased for a term (the “Term”) commencing on the Commencement Date and expiring upon the completion of the Term, or such earlier date on which this Lease terminates pursuant to its terms. The date
upon which this Lease actually terminates, whether by expiration of the Term or earlier termination pursuant to the terms of this Lease, is sometimes referred to in this Lease as the “Termination Date”. Upon delivery of
possession, Landlord shall specify in a written notice to Tenant, substantially in the form of Exhibit B, the Commencement Date, Rent Commencement Date and Expiration Date of this Lease. Such notice shall be delivered promptly after
all of the information set forth in the notice has been determined; provided that Landlord’s failure to do so shall not in any way affect either party’s rights or obligations under this Lease. 

4.2. Failure to Deliver Possession. If for any reason Landlord cannot deliver possession of the Premises or any part thereof to Tenant
on or prior to the Scheduled Date for Delivery of the Premises, then the validity of this Lease and the obligations of Tenant under this 

 
Lease shall not be affected and Tenant shall have no claim against Landlord arising out of Landlord’s failure to deliver possession of the Premises on the Scheduled Date for Delivery of the
Premises. In the event Landlord has not delivered the Premises or any part thereof to Tenant with the Tenant Improvement Work substantially complete within ninety (90) days after the Scheduled Date for Delivery of the Premises, and provided
that said failure to deliver is not due to action or inaction by Tenant, Tenant shall have the right to terminate this Lease solely with respect that that part of the Premises not Delivered by delivery to Landlord of a termination notice (the
“Termination Notice”) which shall be effective ninety (90) days after receipt by Landlord, unless within such 90-day period the Premises are delivered to Tenant. In the event Tenant elects to terminate this Lease, Tenant
must deliver the Termination Notice to Landlord prior to the date the Premises or the part thereof are delivered to Tenant. Upon such termination, neither party shall have any further obligation or liability to the other under this Lease with
respect to that part of the Premises. 
 4.3. Early Possession. Provided that Tenant shall not interfere with Landlord’s
construction of Tenant Improvements, Tenant shall have at least fourteen (14) days prior to the delivery of the Premises to furnish the Premises with its furniture, fixtures, and equipment. Such early possession shall be subject to the terms
and conditions of this Lease, provided that Tenant shall not be obligated to pay Rent (defined in Section 5.2.) except for the cost of services requested by Tenant (e.g. HVAC use). 

4.4. Renewal Option. Tenant shall have one (1) option (the “Renewal Option”) to extend the Term of the
Lease for the entire Premises then being leased to Tenant. The Renewal Option shall be for a three-year term (the “Renewal Term”). The Renewal Term shall commence on the day after the Expiration Date. The Renewal Option shall
be void if a default by Tenant exists, either at the time of exercise of the Renewal Option or the time of commencement of a Renewal Term. The Renewal Option must be exercised, if at all, by written notice from Tenant to Landlord given not more than
twelve (12) months and not less than nine (9) months prior to the expiration of the Term. The Renewal Term shall be upon the same terms and conditions as the original Term, except that (a) the Base Rent payable pursuant to
Section 4.1 with respect to the Renewal Term shall be equal to the greater of (i) the then current Base Monthly Rent, or ii) Prevailing Market Rent as of the commencement of the Renewal Term, as determined pursuant to Exhibit C; (b)
the Base Rent shall escalate over the Renewal Term annually thereafter by 3% per annum; (c) Tenant shall not be entitled to any tenant improvement allowance during the Renewal Term; and (d) from and after the exercise of the
Renewal Option, (i) all references to “Expiration Date” shall be deemed to refer to the last day of the Renewal Term, and (ii) all references to “Term” shall be deemed to include the Renewal Term. The Renewal Option is
personal to Tenant and shall be inapplicable and null and void if Tenant assigns or sublets at least 50% of its interest under this Lease or if the Tenant is not occupying at least 50% of the Premises. 

4.5. Substitution of Space. 

(a) Landlord reserves the right upon one hundred twenty (120) days written notice to Tenant to substitute other premises (the
“Substituted Premises”) for the Premises, solely for the purpose to relocate Tenant for a transaction that is equal to or greater than 100,000 rentable square feet. 

(b) The Substituted Premises shall consist of any other comparable space in the Building or at 2000 Sierra Point Parkway, Brisbane,
provided that the Substituted Premises is substantially similar in size to the Premises, is located on the 3rd floor or higher of 

 
the building, and the Tenant can accommodate Tenant’s intended use and headcount, with a similar number of private offices and other rooms. The monthly Base Rent for the Substituted Premises
shall be at the per rentable square foot rental rate set forth in Section 1 times the rentable area of the Substituted Premises, but in no event will the monthly Base Rent exceed $37,911, as escalated through the term. All other provisions of
this Lease shall remain in full force and effect with respect to the Substituted Premises. 
 (c) Landlord shall pay all costs and
expenses of Tenant incidental to the relocation of Tenant to such Substituted Premises, including but not limited to, the moving expenses and all reasonable costs associated with reinstallation of Tenant’s furniture, telephones, computers and
related IT equipment/infrastructure, and security equipment/infrastructure; provided, however, that Tenant shall not be entitled to any compensation for damages for any interference with or interruption of its business during or resulting from such
relocation. There shall be no abatement of rent payable hereunder or on account of Tenant’s relocation or any recovery for inconvenience or business loss caused to Tenant thereby. 

(d) Tenant shall have the right to refuse to relocate to the Substituted Premises meeting the foregoing requirements by providing
written notice to Landlord within thirty (30) days of receiving Landlord’s notice to substitute the Premises; in such event, Landlord shall have the right to terminate this Lease upon written notice to Tenant, and the new Lease expiration
date shall the later of i) that date that the relocation out of the current Premises was to be completed under Landlord’s original notice to Tenant, or ii) one hundred and twenty (120) days from Landlord’s notice to terminate the
Lease. 
 5. RENT 

5.1. Base Rent. Commencing upon the Rent Commencement Date, and thereafter during the Term, Tenant shall pay to Landlord the monthly
Base Rent specified in Article 1 on or before the first day of each month, in advance, at the address specified for Landlord in Article 1, or at such other place as Landlord designates in writing, without any prior notice or demand and
without any deductions or setoff whatsoever (except as otherwise expressly provided in this Lease). Tenant shall pay the first month’s rent in advance, upon execution of this Lease. If the Rent Commencement Date occurs on a day other than the
first day of a calendar month, or the Termination Date occurs on a day other than the last day of a calendar month, then the Base Rent for such fractional month will be prorated on the basis of the actual number of days in such month. The Rentable
Area of the Premises shall be conclusively presumed to be as stated in Article 1, and shall not be subject to adjustment by either Landlord or Tenant during the Term. 

5.2. Additional Rent. All sums due from Tenant to Landlord or to any third party under the terms of this Lease (other than Base Rent)
shall be additional rent (“Additional Rent”), including without limitation the charges for Tenant’s Pro Rata Share of Operating Expenses {described in Article 7) and all sums incurred by Landlord due to Tenant’s
failure to perform its obligations under this Lease. All Additional Rent that is payable to Landlord shall be paid at the time and place that Base Rent is paid. Landlord will have the same remedies for a default in the payment of any Additional Rent
as for a default in the payment of Base Rent. Together, Base Rent and Additional Rent are sometimes referred to in this Lease as “Rent”. 

 5.3. Late Payment. Any unpaid Rent shall bear interest from the date due until paid at the
lesser of the published “prime” interest rate (that rate quoted by Wells Fargo Bank from time to time as its prime rate) plus six (6) percent (6%) per annum or the then maximum interest rate allowed by law (the
“Interest Rate”). In addition, Tenant recognizes that late payment of any Rent will result in administrative expense to Landlord, the extent of which expense is difficult and economically impracticable to determine.
Therefore, Tenant agrees that if Tenant fails to pay any Rent within five (5) days after its due date, an additional late charge of five percent (5%) of the sums so overdue shall become immediately due and payable; provided,
however, that such late charge shall not be assessed upon Tenant’s first (1st) late payment. Tenant agrees that the late payment charge is a reasonable estimate of the additional
administrative costs and detriment that will be incurred by Landlord as a result of such failure by Tenant. In the event of nonpayment of interest or late charges on overdue Rent, Landlord shall have, in addition to all other rights and remedies,
the rights and remedies provided in this Lease and by law for nonpayment of Rent. 
 5.4. Security Deposit. Concurrently with the
execution of this Lease, Tenant shall deliver to Landlord the cash payment to fulfill the Security Deposit requirement described in Article 1. The Security Deposit shall be held by Landlord as security for the faithful performance of this Lease by
Tenant of all of the terms, covenants and conditions of this Lease. If there is an Event of Default by Tenant with respect to any provisions of this Lease (including but not limited to the payment of Rent); if Tenant files a petition in bankruptcy,
insolvency, reorganization, dissolution or liquidation under any law; makes an assignment for the benefit of its creditors; consents to or acquiesces in the appointment of a receiver of itself or the Premises, or if a court of competent jurisdiction
enters an order or judgment appointing a receiver of Tenant or the Premises; or if a court of competent jurisdiction enters an order or judgment approving a petition filed against Tenant under any bankruptcy, insolvency or liquidation law, then in
any such case Landlord may, without waiving any of Landlord’s other rights or remedies under this Lease, apply the Security Deposit in whole or in part to remedy any failure by Tenant to pay any sums due under this Lease, to repair or maintain
the Premises, to perform any other terms, covenants or conditions contained in this Lease, to compensate Landlord for any loss or damages which Landlord may suffer as a result thereof, including without limitation any lost rent to which Landlord is
entitled in the event the Lease terminates or is rejected as a result of any of the foregoing. Should Landlord so apply any portion of the Security Deposit, Tenant shall replenish the Security Deposit to the original amount within fifteen
(15) days after written demand by Landlord. Landlord shall not be required to keep the Security Deposit separate from its general funds, and Tenant shall not be entitled to interest on the Security Deposit. 

6. USE OF PREMISES AND CONDUCT OF BUSINESS 

6.1. Permitted Use. Tenant may use and occupy the Premises during the Term solely for the uses specified and permitted in Article 1 and
for no other purpose without the prior written consent of Landlord, such consent to be granted or withheld in Landlord’s sole and unfettered discretion. Tenant’s use of the Property shall in all respects comply with all Applicable Laws (as
defined in Section 11.1). 
 6.2. Prohibited Uses. Tenant shall not use the Premises or allow the Premises to be used for any
illegal or immoral purpose, or so as to create waste, or constitute a private or public nuisance. Tenant shall not place any loads upon the floors, walls, or ceiling that endanger the structure, or place any Hazardous Material in the drainage system
of the Premises, or overload existing electrical or other mechanical systems. The maximum headcount that Tenant may have in the Premises is one (1) person per one hundred and fifty 

 
(150) rentable square feet. Tenant shall not use any machinery or equipment that causes any substantial noise or vibration. No waste materials or refuse shall be dumped upon or permitted to
remain upon any part of the Premises or outside of the Premises except in trash containers placed inside exterior enclosures designated by Landlord for that purpose or inside of the Premises where approved by Landlord. No materials, supplies,
equipment, finished products or semi-finished products, raw materials or articles of any nature shall be stored upon or permitted to remain outside the Premises or on any portion of the Common Area unless otherwise approved by Landlord in its sole
discretion. No loudspeaker or other device, system, or apparatus which can be heard outside the Premises shall be used in or at the Premises without the prior written consent of Landlord. No explosives or firearms shall be brought into the Premises.

 7. BUILDING SERVICES; OPERATING EXPENSES 

7.1. Building Services. 

(a) Landlord agrees to furnish Tenant with the following services: (1) Water service for use in the lavatories on each floor on
which the Premises are located; (2) Heat and air conditioning in season during Normal Business Hours, at such temperatures and in such amounts as are standard for comparable buildings or as required by governmental authority. Tenant, upon such
advance notice as is reasonably required by Landlord, shall have the right to receive HVAC service during hours other than Normal Business Hours. Tenant shall pay Landlord the standard charge for the additional service as reasonably determined by
Landlord from time to time (which amount as of the Effective Date is $75.00 per hour per floor); (3) Maintenance and repair of the Property as described in Section 8.1; (4) Janitor service on Business Days. If Tenant’s use, floor
covering or other improvements require special services in excess of the standard services for the Building, Tenant shall pay the additional cost attributable to the special services; (5) Elevator service; (6) Electricity to the Premises
for general office use; and (7) such other services as Landlord reasonably determines are necessary or appropriate for the Property. 

(b) Tenant shall have access to the Premises 24 hours per day, 7 days per week. 

(c) Landlord’s failure to furnish, or any interruption or termination of, services due to the application of Applicable Laws, the
failure of any equipment, the performance of repairs, improvements or alterations, or the occurrence of any event or cause beyond the reasonable control of Landlord shall not render Landlord liable to Tenant, constitute a constructive eviction of
Tenant, give rise to an abatement of Rent, nor relieve Tenant from the obligation to fulfill any covenant or agreement, subject only to the provisions of Section 17.1. 

7.2. Operating Expenses. “Operating Expenses” means the total costs and expenses paid or incurred by Landlord
in connection with the ownership, management, operation, maintenance, repair and replacement of the Property, including, without limitation, all costs of: 

(a) taxes, assessments and charges levied upon or with respect to the Property or any personal property of Landlord used in the
operation of the Property, or on Landlord’s interest in the Property or its personal property (“Real Estate Taxes”). Real Estate Taxes shall include, without limitation, all general real property taxes and general and
special assessments, charges, fees, or assessments for transit, housing, police, fire, or other 

 
governmental services or purported benefits to the Property or the occupants thereof, service payments in lieu of taxes that are now or hereafter levied or assessed against Landlord by the United
States of America, the State of California or any political subdivision thereof, or any other political or public entity, and shall also include any other tax, assessment or fee, however described, that may be levied or assessed as a substitute for,
or as an addition to, in whole or in part, any other Real Estate Taxes, whether or not now customary or in the contemplation of the parties as of the Effective Date. Real Estate Taxes shall also include reasonable legal fees, costs, and
disbursements incurred in connection with proceedings to contest, determine, or reduce Real Estate Taxes. Real Estate Taxes shall not include franchise, transfer, succession, gift, inheritance, gross receipts or capital stock taxes or income taxes
measured by the net income of Landlord unless, due to a change in the method of taxation, any of such taxes is levied or assessed against Landlord as a substitute for, or as an addition to, in whole or in part, any other tax that would otherwise
constitute a Real Estate Tax; 
 (b) repair, maintenance, replacement and supply of air conditioning, electricity, steam, water,
heating, ventilating, mechanical, escalator and elevator systems, sanitary and storm drainage systems and all other utilities and mechanical systems (the “Building Systems”); 

(c) landscaping and gardening of the Common Area; 

(d) lighting, repaving, repairing, maintaining and restriping of parking areas and sidewalks; provided, however, the cost of any
capital improvements shall only be included in Operating Expenses to the extent provided in Section 7.2(n) below; 
 (e)
lighting, repairs and maintenance to the Common Area; 
 (f) repair, maintenance and replacement of any security systems and
fire protection systems installed in the Premises; provided, however, the cost of any capital improvements shall only be included in Operating Expenses to the extent provided in Section 7.2(n) below; 

(g) general maintenance, janitorial services, trash removal, cleaning and service contracts and the cost of all supplies, tools and
equipment required in connection therewith; 
 (h) all premiums and costs for insurance carried by Landlord on the Premises, the
Common Area and the Property, or in connection with the use or occupancy thereof (including all amounts paid as a result of loss sustained that would be covered by such policies but for deductibles or self-insurance provisions), including, but not
limited to, the premiums and costs of fire and extended coverage, earthquake, vandalism and malicious mischief, public liability and property damage, worker’s compensation insurance, rental income insurance and any other insurance commonly
carried by prudent owners of comparable buildings, provided, however, that the Landlord may, but shall not be obligated to carry earthquake insurance; 

(i) wages, salaries, payroll taxes and other labor costs and employee benefits for all persons engaged in the operation, management,
maintenance and security of the Property; 

 (j) management fees at commercially reasonable rates (whether or not Landlord employs a
third party managing agent); 
 (k) fees, charges and other costs of all independent contractors engaged by Landlord; 

(I) license, permit and inspection fees; 

(m) the cost of supplies, tools, machines, materials and equipment used in operation and maintenance of the Common Area; 

(n) any capital improvements to the Property; provided that the cost of any such capital improvements shall be amortized over the
useful life of the improvement in question (determined in accordance with GAAP), together with interest on the unamortized balance at the Interest Rate; 

(o) the cost of contesting the validity or applicability of any governmental enactments that may affect Operating Expenses, including,
without limitation, the costs of audits by certified public accountants of Operating Expense records; 
 (p) audit and bookkeeping
fees, legal fees and expenses incurred in connection with the operation or management of the Property; 
 (q) legal and accounting
services for the Property; and 
 (r) any other expenses of any kind whatsoever reasonably incurred in connection with the
management, operation, maintenance, repair and replacement of the Property. 
 Notwithstanding anything in the definition of Operating
Expenses to the contrary, Operating Expenses shall not include the following: 
 (i) Costs actually reimbursed to Landlord by insurance
proceeds for the repair of damage to the Property; 
 (ii) Financing and refinancing costs, interest, principal, points and fees on debts
or amortization on any mortgage or mortgages or any other debt instrument encumbering the Property; 
 (iii) legal fees, leasing
commissions, cash allowances, buy-out amounts, advertising expenses, promotional expenses, and other costs of a similar nature incurred in the leasing of space at the Property; 

(iv) ground rent or any other payments paid under any present or future ground or overriding or underlying lease and/or grant affecting the
Property and/or the Premises (other than payments which, independent of such lease, would constitute an Operating Expense hereunder); and 

(v) costs incurred due to a violation of the provisions of this Lease by Landlord; and 

(vi) costs arising from the presence of any Hazardous Materials or violation of Environmental Laws as of or prior to the Commencement Date or
caused solely by Landlord or its agents. 

 7.3. Occupancy Assumption. If the Building is not at least 100% occupied during any
calendar year or if Landlord is not supplying services to at least 100% of the total Rentable Area of the Building at any time during a calendar year, Operating Expenses shall, at Landlord’s option, be determined as if the Building had been
100% occupied and Landlord had been supplying services to 100% of the Rentable Area of the Building during that calendar year. If Tenant pays for its Pro Rata Share of Operating Expenses based on increases over a “Base Year” and
Operating Expenses for a calendar year are determined as provided in the prior sentence, Operating Expenses for the Base Year shall also be determined as if the Building had been 100% occupied and Landlord had been supplying services to 100% of the
Rentable Area of the Building. The extrapolation of Operating Expenses under this Section shall be performed by appropriately adjusting the cost of those components of Operating Expenses that are impacted by changes in the occupancy of the Building.

 7.4. Payment of Operating Expenses. Tenant shall pay to Landlord, as Additional Rent, Tenant’s Pro Rata Share of the amount,
if any, by which Operating Expenses for each calendar year during the Term exceed Operating Expenses for the Base Year (“Expense Excess”). Tenant shall pay one twelfth of Tenant’s Pro Rata Share of the Expense Excess in
advance, on or before the first day of each month in an amount estimated by Landlord as stated in a written notice to Tenant. Landlord may by written notice to Tenant revise such estimates from time to time and Tenant shall thereafter make payments
on the basis of such revised estimates. With reasonable promptness after the expiration of each calendar year, Landlord will furnish Tenant with a statement (“Landlord’s Expense Statement”) setting forth in reasonable
detail the actual Operating Expenses for the prior calendar year and the amount of Tenant’s Pro Rata Share of the Expense Excess. If Tenant’s Pro Rata Share of the actual Expense Excess for such year exceed the estimated amounts paid by
Tenant for such year, Tenant shall pay to Landlord (whether or not this Lease has terminated) the difference between the amount of estimated Tenant’s Pro Rata Share of Expense Excess paid by Tenant and the actual Tenant’s Pro Rata Share of
Expense Excess within thirty (30) days after the receipt of Landlord’s Expense Statement. If the total amount paid by Tenant for any year exceeds the actual amount due from Tenant for that year, the excess shall be credited against the
next installments of Additional Rent due from Tenant to Landlord, or, if after the Termination Date, the excess shall first be credited against any unpaid Rent and any remaining excess shall be refunded promptly to Tenant. The tenant reserves the
right to audit such operating expenses before an increase in the Operating Expenses is charged to the tenant. 
 7.5. Proration. If
either the Rent Commencement Date or the Termination Date occurs on a date other than the first or last day, respectively, of a calendar year, Tenant’s Pro Rata Share of Expense Excess for the year in which the Rent Commencement Date or
Termination Date occurs shall be prorated based on a 365-day year. 
 7.6. Utility Costs. Landlord shall arrange for the following
utilities furnished to or used at the Premises: water, gas, electricity, sewer service and non-hazardous waste pick-up. The costs of such utilities shall be included in Operating Expenses. Tenant shall be
responsible for arranging for telephone and other electronic communications services, at the Premises and shall pay the costs of such utilities directly. Landlord will work in good faith with Tenant to provide access to a cable or satellite TV feed
to the Premises, subject to agreement of the parties with respect to allocation of costs of installation and ongoing monthly service costs. 

 7.7. Taxes on Tenant’s Property and Business. Tenant shall pay prior to delinquency
all taxes levied or assessed by any local, state or federal authority upon the conduct of Tenant’s business in the Premises or upon Tenant’s Property (as defined in Section 9.5) and shall deliver satisfactory evidence of such payment
to Landlord. If the assessed value of the Property is increased by the inclusion of a value placed upon Tenant’s Property, Tenant shall pay to Landlord, upon written demand, the taxes so levied against Landlord, or the portion of
Landlord’s taxes resulting from said increase in assessment, as determined from time to time by Landlord. 
 7.8. Electricity
Reimbursement for Tenant’s Special Systems. Landlord shall have the right to require that Tenant reimburse Landlord for the electricity use of Tenant’s Special Systems which utilize a large amount of electricity, which may include but
are not limited to Tenant’s Server Room Computers, Server Room Cooling Systems, or other systems not typical for general office use (“Tenant’s Special Systems”). Landlord may require Tenant to measure such
electricity use using E-Mon D-Mon kWh Meters, and the electricity reimbursement shall be calculated by Landlord based on the actual electric rates paid by the Property. 

7.9. Energy and Resource Consumption. Landlord may voluntarily cooperate in a reasonable manner with the efforts of governmental
agencies and/or utility suppliers in reducing energy or other resource consumption within the Property. Tenant shall not be entitled to terminate this Lease or to any reduction in or abatement of rent by reason of such compliance or cooperation.
Tenant agrees at all times to cooperate fully with Landlord and to abide by all reasonable rules established by Landlord (i) in order to maximize the efficient operation of the electrical, heating, ventilating and air conditioning systems and
all other energy or other resource consumption systems with the Property and/or (ii) in order to comply with the requirements and recommendations of utility suppliers and governmental agencies regulating the consumption of energy and/or other
resources. 
 8. REPAIRS, MAINTENANCE AND SERVICES 

8.1. Landlord’s Obligations. Except as specifically provided in this Lease, Landlord shall not be required to furnish any
services, facilities or utilities to the Premises or to Tenant, and Tenant assumes full responsibility for obtaining and paying for all services, facilities and utilities to the Premises. Landlord will repair, replace and maintain the Building
Systems, the Common Area, and the structural portions of the Building and Premises, including, without limitation, the foundation, floor/ceiling slabs, roof, curtain wall, exterior glass and mullions, columns, beams, shafts (including elevator
shafts), Common Area stairs, Building standard stairwells (but not stairs or stairwells installed by the Tenant or any former tenant) and elevators (collectively, the “Building Structure”). Landlord shall also provide the
Premises with interior and exterior window washing services and janitorial service and shall provide the Common Areas with landscaping services. Tenant shall notify Landlord in writing when it becomes aware of the need for any repair, replacement or
maintenance that is Landlord’s responsibility under this Section of which it becomes aware. The costs of such repair, replacement and maintenance shall be included in Operating Expenses to the extent provided in Article 7; provided that,
subject to Section 13.5, Tenant _ shall reimburse Landlord in full and within fifteen 

 
(15) days after written demand for the cost of any repair to the Property, Building Structure or Building Systems which is attributable to misuse by Tenant or Tenant’s Agents. The
reimbursement shall be Additional Rent. Tenant hereby waives and releases any right it may have under any law, statute or ordinance now or hereafter in effect to make any repairs that are Landlord’s obligation under this Section. 

8.2. Tenant’s Obligations. Except as provided in Section 8.1, Tenant assumes full responsibility for the repair, replacement
and maintenance of the Premises, including, without limitation, all mechanical and other systems and equipment (including but not limited to any server cooling system(s) and kitchenette(s)) installed within the Premises (“Tenant
Systems”). Tenant shall take good care of the Premises and the Tenant Systems and keep the Premises and the Tenant Systems in good working order and in a clean, safe and sanitary condition. All repairs and replacements by Tenant
for which Tenant is responsible are collectively referred to as the “Tenant Obligations” and shall be made and performed: (a) at Tenant’s cost and expense, and at such time and in such manner as Landlord may
designate, (b) by contractors or mechanics approved by Landlord in accordance with Section 9.3, (c) so that same shall be at least equal in quality, value and utility to the original work or installation, (d) in a manner and
using equipment and materials that will not impair the operation of or damage the Building Systems, and (e) in accordance with Article 9 (if applicable}, and all Applicable Laws. Tenant shall cooperate fully and in good faith with Landlord and
Landlord’s property manager in the performance of all such repairs and replacements by Tenant, and shall perform all such work and activities diligently and expeditiously to completion, and in a manner consistent with Class A office
buildings located in San Mateo County, California. Tenant shall reimburse Landlord within fifteen (15) days after written demand as Additional Rent for any out-of-pocket expenses incurred by Landlord in
connection with any repairs or replacements required to be made by Tenant, including, without limitation, any reasonable fees charged by Landlord’s contractors to review plans and specifications prepared by Tenant. 

8.3. Security. Tenant shall be solely responsible for the security of the Premises and Tenant’s Agents while in or about the
Premises. Any security services provided to the Property by Landlord shall be at Landlord’s sole discretion and Landlord shall not be liable to Tenant or Tenant’s Agents for any failure to provide security services or any loss, injury or
damage suffered as a result of a failure to provide security services. 
 8.4. Landlord’s Right To Cure Defaults. In the event
Tenant fails to perform or adequately perform any of Tenant’s Obligations as reasonably determined by Landlord, Landlord, in its sole and absolute discretion, and upon fifteen (15) days written notice to Tenant, may terminate Tenant’s
right to perform Tenant’s Obligations, and Landlord shall then assume for itself or assign to Landlord’s property manager all responsibility for the performance of all such Tenant’s Obligations for the remainder of the Term, the cost
of which shall be included within the definition of Operating Expenses. 
 8.5. Special Services. If Tenant requests any services
from Landlord other than those for which Landlord is obligated under this Lease, Tenant shall make its request in writing and Landlord may elect in its sole discretion whether to provide the requested services. If Landlord provides any special
services to Tenant, Landlord shall charge Tenant for such services at the prevailing rate being charged for such services by other property owners and property managers of comparable buildings in the area of the Property, and Tenant shall pay the
cost of such services as Additional Rent within fifteen (15) days after receipt of Landlord’s invoice. 

 9. TENANT IMPROVEMENT WORK; ALTERATIONS 

9.1. Tenant Improvements. Landlord shall Deliver the Premises to Tenant with existing improvements in its “as-is” condition
and Landlord shall have no other obligation to improve the Premises, with the sole exception of the “Tenant Improvement Work” which shall be performed by Landlord at Landlord’s expense pursuant to the terms of the
“Work Letter” attached hereto as Exhibit E. 
 9.2. Alterations by Tenant. Tenant shall not make or permit
any alterations to the Building Systems, and shall not make or permit any alterations, installations, additions or improvements, structural or otherwise (collectively, “Alterations”) in or to the Premises or the Building
without Landlord’s prior written consent, which Landlord shall not unreasonably withhold, condition or delay. Landlord shall respond to any request by Tenant to make any Alteration within fifteen (15) days after receipt of such request for
consent from Tenant. Notwithstanding the foregoing, Landlord’s consent shall not be required (a) in the case of interior, cosmetic non-structural Alterations that do not require a permit, or affect the Building Systems, or affect the
entryways or elevators or any other premises in the Building, or (b) in the case of other Alterations that do not exceed a total price of Twenty-Five Fifty Thousand Dollars ($25,000) per project and do not affect the Building Systems or the
structural integrity of the Building. All Alterations shall be done at Tenant’s sole cost and expense, including without limitation the cost and expense of obtaining all permits and approvals required for any Alterations. Tenant shall reimburse
Landlord within fifteen (15) days after written demand as Additional Rent for any out-of-pocket expenses incurred by Landlord in connection with Alterations elected to be made and/or any repairs or replacements required to be made by Tenant,
including, without limitation, any reasonable fees charged by Landlord’s contractors and/or consultants to review plans and specifications prepared by Tenant. 

9.3. Project Requirements. The provisions of this Section 9.3 shall apply to all Alterations, whether or not requiring
Landlord’s approval (unless otherwise noted): 
 (a) Prior to entering into a contract for any Alterations requiring
Landlord’s approval, Tenant shall obtain Landlord’s written approval, which approval shall not be unreasonably withheld, conditioned or delayed, of the identity of each of the design architect and the general contractor. 

(b) Before commencing the construction of any Alterations, Tenant shall procure or cause to be procured the insurance coverage
described below and provide Landlord with certificates of such insurance in form reasonably satisfactory to Landlord. All such insurance shall comply with the following requirements of this Section and of Section 13.2. 

(i) During the course of construction, to the extent not covered by property insurance maintained by Tenant pursuant to Section 13.2,
comprehensive “all risk” builder’s risk insurance, including vandalism and malicious mischief, excluding earthquake and flood, covering all improvements in place on the Premises, all materials and equipment stored at the site and
furnished under contract, and all materials and equipment that are in the process of fabrication at the premises of any third party or that have been placed in transit to the Premises when such fabrication or transit is at the risk of, or when title
to or an insurable interest in such materials or equipment has passed to, Tenant or its construction manager, contractors or subcontractors (excluding any contractors’, subcontractors’ and construction managers’ tools and equipment,
and property owned by the employees of the construction manager, any contractor or any subcontractor), such insurance to be written on a completed value basis in an amount not less than the full estimated replacement value of Alterations. 

 (ii) Commercial general liability insurance covering Tenant, Landlord and each construction
manager, contractor and subcontractor engaged in any work on the Premises, which insurance may be effected by endorsement, if obtainable, on the policy required to be carried pursuant to Section 13.2, including insurance for completed
operations, elevators, owner’s, construction manager’s and contractor’s protective liability, products completed operations for one (1) year after the date of acceptance of the work by Tenant, broad form blanket contractual
liability, broad form property damage and full form personal injury (including but not limited to bodily injury), covering the performance of all work at or from the Premises by Tenant, its construction manager, contractors and subcontractors, and
in a liability amount not less than the amount at the time carried by prudent owners of comparable construction projects, but in any event not less than Three Million Dollars ($3,000,000) combined single limit, which policy shall include for the
mutual benefit of Landlord and Tenant, bodily injury liability and property damage liability, and automobile insurance on any non-owned, hired or leased automotive equipment used in the construction of any work. 

(iii) Workers’ Compensation Insurance approved by the State of California, in the amounts and coverages required under workers’
compensation, disability and similar employee benefit laws applicable to the Premises, and Employer’s Liability Insurance with limits not less than One Million Dollars ($1,000,000) or such higher amounts as may be required by law. 

(c) All construction and other work in connection with any Alterations shall be done at Tenant’s sole cost and expense and in a
prudent and first class manner. Tenant shall construct the Alterations in accordance with all Applicable Laws, and with plans and specifications that are in accordance with the provisions of this Article 9 and all other provisions of this Lease.

 (d) Prior to the commencement of any Alteration, Landlord shall have the right to post in a conspicuous location on the Premises
and to record in the public records a notice of Landlord’s nonresponsibility. Tenant covenants and agrees to give Landlord at least ten (10) days prior written notice of the commencement of the Tenant Improvement Work and any such
Alteration in order that Landlord shall have sufficient time to post such notice. 
 (e) Tenant shall take all necessary safety
precautions during any construction. 
 (f) With regards to any work to be performed to or needed by the Building Systems and
subsystems, Tenant shall use those subcontractors that regularly maintain and manage such systems, and such work will include design, components, distribution, and installation to meet Landlord’s specifications for the operations of the
Building. 
 (g) With regard to any Alterations in excess of Twenty-Five Thousand Dollars ($25,000), Tenant shall prepare and
maintain (i) on a current basis during construction, annotated plans and specifications showing clearly all changes, revisions and substitutions during construction, and (ii) upon completion of construction of the Alterations, as-built
drawings showing clearly all changes, revisions and substitutions during construction, including, without limitation, field changes and the final location of all mechanical equipment, utility lines, ducts, outlets, structural members, walls,
partitions and other significant features. These as-built 

 
drawings and annotated plans and specifications shall be kept at the Premises and Tenant shall update them as often as necessary to keep them current. The as-built drawings and annotated plans
and specifications shall be made available for copying and inspection by Landlord at all reasonable times. Within sixty (60) days after the Alterations have been substantially completed, Tenant shall, at its cost, make a copy of the as-built
drawings and annotated plans and specifications and deliver the same to Landlord. 
 (h) Upon completion of the construction of any
Alterations in excess of Twenty-Five Thousand Dollars ($25,000) during the Term, Tenant shall file for recordation, or cause to be filed for recordation, a notice of completion and shall deliver to Landlord evidence satisfactory to Landlord of
payment of all costs, expenses, liabilities and liens arising out of or in any way connected with such construction (except for liens that are contested in the manner provided herein). 

9.4. Ownership of Improvements. Except as provided in Section 9.5, all Tenant Improvement Work, Alterations, and any other
appurtenances, fixtures, improvements, equipment, additions and property permanently attached to or installed in the Premises at the commencement of or during the Term, shall at the end of the Term become Landlord’s property without
compensation to Tenant, or be removed in accordance with this Section. Upon written request by Tenant, Landlord shall notify Tenant in writing at the time of Landlord’s approval of the Alterations, whether or not the proposed Alterations will
be required to be removed by Tenant at the end of the Term and Tenant shall have no obligation to remove any Alterations that Landlord has not designated in writing for removal. Tenant shall repair or pay the cost of repairing any damage to the
Property caused by the removal of Alterations. If Tenant fails to perform its repair obligations, without limiting any other right or remedy, Landlord may on five (5) Business Days prior written notice to Tenant perform such obligations at
Tenant’s expense and Tenant shall reimburse Landlord within thirty (30) days after demand for all out-of-pocket costs and expenses incurred by Landlord in connection with such repair. Tenant’s obligations under this Section shall
survive the termination of this Lease. 
 9.5. Tenant’s Personal Property. All furniture, trade fixtures, furnishings, equipment
and articles of movable personal property installed in the Premises by or for the account of Tenant (except for ceiling and related fixtures, built-in cabinetry and appliances, HVAC equipment and floor coverings, which shall become the property of
Landlord at the end of the Term), and which can be removed without structural or other material damage to the Property (collectively, “Tenant’s Property”) shall be and remain the property of Tenant and may be removed by
it at any time during the Term. Tenant shall remove from the Premises all Tenant’s Property on or before the Termination Date, except such items as the parties have agreed pursuant to the provisions of this Lease or by separate agreement are to
remain and to become the property of Landlord. Upon the direction of Landlord, Tenant shall remove its data cabling and related fixtures, remove and/or repair any other tenant finishes, and return the Premises similar to its original condition.
Tenant shall repair or pay the cost of repairing any damage to the Property resulting from such removal, and the provisions of Section 9.5 above shall apply in the event Tenant fails to do so. Any items of Tenant’s Property which remain in
the Premises after the Termination Date may, on five (5) Business Days prior written notice to Tenant, at the option of Landlord, be deemed abandoned and in such case may either be retained by Landlord as its property or be disposed of, without
accountability, at Tenant’s expense in such manner as Landlord may see fit. 

 10. LIENS 

Tenant shall keep the Premises free from any liens arising out of any work performed, material furnished or obligations incurred by or for
Tenant. If Tenant shall not, within ten (10) Business Days following notice of the imposition of any such lien, cause the lien to be released of record by payment or posting of a proper bond, Landlord shall have, in addition to all other
remedies provided in this Lease and by law, the right but not the obligation to cause any such lien to be released by such means as it shall deem proper, including payment of the claim giving rise to such lien. All such sums paid by Landlord and all
expenses incurred by it in connection therewith (including, without limitation, reasonable counsel fees) shall be payable to Landlord by Tenant upon demand with interest from the date incurred at the Interest Rate. Landlord shall have the right at
all times to post and keep posted on the Premises any notices permitted or required by law or that Landlord shall deem proper for the protection of Landlord, the Premises and the Property from mechanics’ and materialmen’s liens, as more
specifically provided in Section 9.4(d). 
 11. COMPLIANCE WITH LAWS AND INSURANCE REQUIREMENTS 

11.1. Applicable Laws. Tenant, at Tenant’s cost and expense, shall comply with all applicable laws, statutes, codes, ordinances,
orders, rules, regulations, conditions of approval, and requirements, of all federal, state, county, municipal and other governmental authorities and the departments, commissions, boards, bureaus, instrumentalities, and officers thereof, and all
administrative or judicial orders or decrees and all permits, licenses, approvals and other entitlements issued by governmental entities, and rules of common law, relating to or affecting the Premises or the use, operation or occupancy of the
Premises, whether now existing or hereafter enacted (collectively, “Applicable Laws”). Without limiting the foregoing, but specifically excluding the Tenant Improvement Work to be performed by Landlord, Tenant shall be
solely responsible for compliance with and shall make or cause to be made all such improvements and alterations to the Premises (including, without limitation, removing barriers and providing alternative services) as shall be required to comply with
all applicable building codes, laws and ordinances relating to public accommodations, including the Americans with Disabilities Act of 1990, 42 U.S.C. §§ 12111 et seq. (the “ADA”), and the ADA Accessibility
Guidelines promulgated by the Architectural and Transportation Barriers Compliance Board, the public accommodations title of the Civil Rights Act of 1964, 42 U.S.C. §§ 2000a et. seq., the Architectural Barriers Act of 1968, 42 U.S.C.
§§ 4151 et. seq., as amended, Title V of the Rehabilitation Act of 1973, 29 U.S.C. §§ 790 et. seq., the Minimum Guidelines and Requirements for Accessible Design, 36 C.F.R. Part 1190, the Uniform Federal Accessibility Standards,
and Title 24 of the California Code of Regulations, as the same may be amended from time to time, or any similar or successor laws, ordinances and regulations, now or hereafter adopted. Tenant’s liability shall be primary and Tenant shall
indemnify Landlord in accordance with Section 13.1 in the event of any failure or alleged failure of Tenant to comply with Applicable Laws. Any work or installations made or performed by or on behalf of Tenant or any person or entity claiming
through or under Tenant pursuant to the provisions of this Section shall be made in conformity with and subject to the provisions of Article 9. 

11.2. Insurance Requirements. Tenant shall not do anything, or permit anything to be done, in or about the Premises that would:
(a) invalidate or be in conflict with the provisions of or cause any increase in the applicable rates for any fire or other insurance policies covering the Property or any property located therein (unless Tenant pays for such increased costs),
or (b) result in a refusal by fire insurance companies of good standing to insure the Property or any such property in amounts reasonably satisfactory to Landlord (which amounts shall be comparable to the amounts required by comparable
landlords of comparable buildings, or (c) subject Landlord to any liability or responsibility for injury to any person or 

 
property by reason of any business operation being conducted in the Premises. Tenant, at Tenant’s expense, shall comply with all rules, orders, regulations or requirements of the American
Insurance Association (formerly the National Board of Fire Underwriters) and with any similar body that shall hereafter perform the function of such Association, to the extent specifically pertaining to the Premises. 

12. HAZARDOUS MATERIALS 

12.1. Definitions. As used in this Lease, the following terms shall have the following meanings: 

(a) “Environmental Activity” means any use, treatment, keeping, storage, holding, release, emission,
discharge, manufacturing, generation, processing, abatement, removal, disposition, handling, transportation, deposit, leaking, spilling, injecting, dumping or disposing of any Hazardous Materials from, into, on or under the Property, and shall
include the exacerbation of any pre-existing contamination by Tenant or any of Tenant’s Agents. 
 (b)
“Environmental Laws” mean all Applicable Laws, now or hereafter in effect, relating to environmental conditions, industrial hygiene or Hazardous Materials on, under or about the Property, including without limitation the
Comprehensive Environmental Response, Compensation and Liability Act of 1980, as amended, 42 U.S.C. Section 9601, et seq., the Hazardous Materials Transportation Act, 49 U.S.C. Section 1801, et seq., the Solid Waste Disposal Act, 42 U.S.C.
Section 6901, et seq., the Clean Water Act, 33 U.S.C. Section 1251, et seq., the Clean Air Act, 42 U.S.C. Section 7401, et seq., the Toxic Substances Control Act, 15 U.S.C. Section 2601 through 2629, the Safe Drinking Water Act,
42 U.S.C. Sections 300f through 300j, and any similar state and local laws and ordinances and the regulations now or hereafter adopted and published and/or promulgated pursuant thereto. 

(c) “Hazardous Material” means any chemical, substance, medical or other waste, living organism or combination
thereof which is or may be hazardous to the environment or human or animal health or safety due to its radioactivity, ignitability, corrosivity, reactivity, explosivity, toxicity, carcinogenicity, mutagenicity, phytotoxicity, infectiousness or other
harmful or potentially harmful properties or effects. Hazardous Materials shall include, without limitation, petroleum hydrocarbons, including MTBE, crude oil or any fraction thereof, asbestos, radon, polychlorinated biphenyls (PCBs), methane, lead,
urea, formaldehyde foam insulation, microbial matter (including mold) and all substances which now or in the future may be defined as “hazardous substances,” “hazardous wastes,” “extremely hazardous wastes,”
“hazardous materials,” “toxic substances,” “infectious wastes,” “biohazardous wastes,” “medical wastes,” “radioactive wastes” or which are otherwise listed, defined or regulated in any
manner pursuant to any Environmental Laws. 
 (d) “Tenant’s Hazardous Materials” means any Hazardous
Materials resulting from the Environmental Activity by Tenant or any of Tenant’s Agents. 
 12.2. Environmental Release.
Landlord hereby informs Tenant that detectable amounts of Hazardous Materials may have come to be located on, beneath and/or in the vicinity of the Premises, and copies of Landlord’s Phase I Environmental Report shall be provided to Tenant
at its request. Tenant has made such investigations and inquiries as it deems appropriate to ascertain the effects, if any, of such substances and contaminants on its operations and persons using the Property. Landlord makes no representation or
warranty with regard to the environmental condition of the Property. Tenant hereby releases Landlord and 

 
Landlord’s officers, directors, trustees, agents and employees from any and all claims, demands, debts, liabilities, and causes of action of whatever kind or nature, whether known or unknown
or suspected or unsuspected which Tenant or any of Tenant’s Agents may have, claim to have, or which may hereafter accrue against the released parties or any of them, arising out of or relating to or in any way connected with Hazardous
Materials presently in, on or under, or now or hereafter emanating from or migrating onto the Property. In connection with such release, Tenant hereby waives any and all rights conferred upon it by the provisions of Section 1542 of the
California Civil Code, which reads as follows: 
 A general release does not extend to claims which the creditor does not know or suspect to
exist in his favor at the time of executing the release, which if known by him must have materially affected his settlement with the debtor. 

12.3. Use of Hazardous Materials. Tenant shall not cause or permit any Hazardous Materials to be used, stored, discharged, released or
disposed of in the Premises or cause any Hazardous Materials to be used, stored, discharged, released or disposed of in, from, under or about, the Property, or any other land or improvements in the vicinity of the Property, excepting only the types
and minor quantities of Hazardous Materials which are normally used in connection with general office uses and then only in strict accordance with all Applicable Laws, including all Environmental Laws. As of the Commencement Date, Tenant shall
provide Landlord a complete list of all Hazardous Materials (including MSDS sheets for all such Hazardous Materials} used or stored by Tenant or any of Tenant’s Agents or subtenants at the Premises, excluding standard janitorial and office
products. Throughout the Term, Tenant shall continue to update this list so that it remains current. Without limiting the foregoing, Tenant shall, at its own expense, procure, maintain in effect and comply with all conditions of any and all permits,
licenses, and other governmental and regulatory approvals required for Tenant’s use of Hazardous Materials at the Premises, including, without limitation, discharge of appropriately treated materials or wastes into or through any sanitary sewer
serving the Premises. Tenant shall in all respects handle, treat, deal with and manage any and all Tenant’s Hazardous Materials in total conformity with all Environmental Laws and prudent industry practices regarding management of such
Hazardous Materials. 
 12.4. Remediation of Hazardous Materials. Tenant shall, upon demand of Landlord, and at Tenant’s sole
cost and expense, promptly take all actions to remediate the Property from the effects of any Tenant’s Hazardous Materials. Such actions shall include, but not be limited to, the investigation of the environmental condition of the Property, the
preparation of any feasibility studies, reports or remedial plans, and the performance of any cleanup, remediation, containment, operation, maintenance, monitoring or restoration work, whether on or off of the Property. Tenant shall take all actions
necessary to remediate the Property from the effects of such Tenant’s Hazardous Materials to a condition allowing unrestricted use of the Property (i.e. to a level that will allow any future use of the Property, including residential, hospital,
or day care, without any engineering controls or deed restrictions), notwithstanding any lesser standard of remediation allowable under Applicable Laws. All work shall be performed by one or more contractors selected by Tenant and reasonably
approved in advance and in writing by Landlord. Tenant shall proceed continuously and diligently with such investigatory and remedial actions, provided that in all cases such actions shall be in accordance with all Applicable Laws. Any such actions
shall be performed in a good, safe and workmanlike manner. Tenant shall pay all costs in connection with such investigatory and remedial activities, including but not limited to all power and utility costs, and any and all taxes or fees that may be
applicable to such activities. Tenant shall promptly 

 
provide to Landlord copies of testing results and reports that are generated in connection with the above activities and any that are submitted to any governmental entity. Promptly upon
completion of such investigation and remediation, Tenant shall permanently seal or cap all monitoring wells and test holes in accordance with sound engineering practice and in compliance with Applicable Laws, remove all associated equipment,
and restore the Property to the maximum extent possible, which shall include, without limitation, the repair of any surface damage, including paving, caused by such investigation or remediation. 

12.5. Indemnity. Tenant shall indemnify, defend (by counsel reasonably acceptable to Landlord), protect and hold Landlord and
Landlord’s trustees, directors, officers, agents and employees and their respective successors and assigns (collectively, “Landlord’s Agents”), free and harmless from and against any and all claims, liabilities,
penalties, forfeitures, losses or expenses (including reasonable attorneys’ and consultants’ fees and oversight and response costs) to the extent arising from (a) Environmental Activity by Tenant or Tenant’s Agents; or
(b) failure of Tenant or Tenant’s Agents to comply with any Environmental Law with respect to Tenant’s Environmental Activity; or (c) Tenant’s failure to remove Tenant’s Hazardous Materials as required in
Section 12.4. Tenant’s obligations hereunder shall include, but not be limited to, the burden and expense of defending all claims, suits and administrative proceedings (with counsel reasonably approved by Landlord), even if such claims,
suits or proceedings are groundless, false or fraudulent; conducting all negotiations of any description; and promptly paying and discharging when due any and all judgments, penalties, fines or other sums due against or from Landlord or the
Premises. Prior to retaining counsel to defend such claims, suits or proceedings, Tenant shall obtain Landlord’s written approval of the identity of such counsel, which approval shall not be unreasonably withheld, conditioned or delayed. In the
event Tenant’s failure to surrender the Premises at the expiration or earlier termination of this Lease free of Tenant’s Hazardous Materials prevents Landlord from reletting the Premises, or reduces the fair market and/or rental
value of the Premises or any portion thereof, Tenant’s indemnity obligations shall include all losses to Landlord arising therefrom. 

12.6. No Lien. Tenant shall not suffer any lien to be recorded against the Property as a consequence of any Tenant’s Hazardous
Materials, including any so-called state, federal or local “super fund” lien related to the remediation of any Tenant’s Hazardous Materials in or about the Property. 

12.7. Investigation. Landlord shall have the right to enter and conduct an inspection of the Premises or the Property, including
invasive tests, at any reasonable time and upon reasonable advance notice, to determine whether Tenant is complying with the terms of this Lease, including but not limited to the compliance of the Property and the Premises and the activities thereon
with Environmental Laws (the “Environmental Investigation”). Landlord shall have the right, but not the obligation, to retain at its expense an independent professional consultant to enter the Property and/or the Premises to
conduct such an inspection, and to review any report prepared by or for Tenant concerning such compliance. In the event the Environmental Investigation identifies any deficiencies in the compliance of the Property and/or the Premises with
Environmental Laws due to any Environmental Activity by Tenant or Tenant’s Agents, Tenant shall promptly correct any such deficiencies identified in the Environmental Investigation, and document to Landlord that corrective action has been
taken. In such event, Tenant shall also reimburse Landlord for the reasonable cost of the Environmental Investigation. If the Environmental Investigation identifies any such deficiency in compliance of the Property and/or the Premises with
Environmental Laws due to any Environmental Activity by Tenant or Tenant’s Agents, then, within nine (9) months of the date of the Environmental Investigation, Landlord may request a detailed review of the status of such violation by a
consultant selected 

 
by Landlord (the “Supplemental Investigation”). Tenant shall pay for the reasonable cost of any Supplemental Investigation. A copy of the Supplemental Investigation shall
be promptly supplied to Landlord and Tenant when it becomes available. 
 12.8. Right to Remediate. Should
Tenant fail to perform or observe any of its obligations or agreements pertaining to Hazardous Materials or Environmental Laws, then Landlord shall have the right, but not the obligation, without limitation of any other rights of Landlord hereunder,
to enter the Premises personally or through Landlord’s agents, employees and contractors and perform the same. Tenant agrees to indemnify Landlord for the costs thereof and liabilities therefrom as set forth above in this Article 12. 

12.9. Notices. Tenant shall immediately notify Landlord of any inquiry, test, claim, investigation or enforcement proceeding by or
against Tenant or the Premises or the Property known to Tenant concerning any Hazardous Materials. Tenant shall immediately notify Landlord of any release or discharge of Hazardous Materials on, in under or about the Property. Tenant acknowledges
that Landlord, as the owner of the Property, shall have the sole right at its election and at Tenant’s expense, to negotiate, defend, approve and appeal any action taken or order issued with regard to Tenant’s Hazardous Materials by any
applicable governmental authority. 
 12.10. Surrender. Tenant shall surrender the Property and the Premises to Landlord, upon the
expiration or earlier termination of the Lease, free of Tenant’s Hazardous Materials in accordance with the provisions of this Article 12. 

12.11. Survival; Insurance. The provisions of this Article 12 shall survive the expiration or earlier termination of this Lease. The
provisions of Article 13 (Insurance) shall not limit in any way Tenant’s obligations under this Article 12. 
 13. INDEMNITY;
INSURANCE 
 13.1. Indemnity. Tenant shall indemnify, protect, defend and save and hold Landlord and Landlord’s Agents
harmless from and against any and all losses, costs, liabilities, claims, judgments, liens, damages (including consequential damages) and expenses, including, without limitation, reasonable attorneys’ fees and costs and reasonable investigation
costs, incurred in connection with or arising from: (a) any default by Tenant in the observance or performance of any of the terms, covenants or conditions of this Lease on Tenant’s part to be observed or performed, or (b) the use or
occupancy or manner of use or occupancy of the Property by Tenant and Tenant’s Agents, (c) the condition of the Premises, and any occurrence in the Premises (including injury to or death of any person, or damage to property) from any cause
whatsoever, except to the extent caused by the negligence or willful misconduct of Landlord, and (d) any acts or omissions or negligence of Tenant or of Tenant’s Agents, in, on or about the Property. In case any action or proceeding be
brought, made or initiated against Landlord relating to any matter covered by Tenant’s indemnification obligations under this Section or under Section 12.5, Tenant, upon notice from Landlord, shall at its sole cost and expense, resist or
defend such claim, action or proceeding by counsel approved by Landlord. Notwithstanding the foregoing, Landlord may retain its own counsel to defend or assist in defending any claim, action or proceeding involving potential liability of Five
Million Dollars ($5,000,000) or more. Tenant’s obligations under this Section shall survive the expiration or earlier termination of this Lease. 

 13.2. Insurance. Tenant shall procure at its sole cost and expense and keep in effect
during the Term: 
 (a) commercial general liability insurance covering Tenant’s operations in the Premises and the use and
occupancy of the Premises and the Property and any part thereof by Tenant. Such insurance shall include broad form contractual liability insurance coverage insuring Tenant’s obligations under this Lease. Such coverage shall be
written on an “occurrence” form and shall have a minimum combined single limit of liability of not less than three million dollars ($3,000,000.00). Tenant’s policy shall be written to apply to all bodily injury, property damage,
personal injury and other covered loss (however occasioned) occurring during the policy term, with at least the following endorsements to the extent such endorsements are generally available: (i) deleting any employee exclusion on
personal injury coverage, (ii) including employees as additional insureds, (iii) providing broad form property damage coverage and products completed operations coverage (where applicable), and (iv) deleting any liquor
liability exclusions. Such insurance shall name Landlord and any other party designated by Landlord as an additional insured, shall specifically include the liability assumed hereunder by Tenant, shall provide that it is primary insurance, shall
provide for severability of interests, shall further provide that an act or omission of one of the named insureds which would void or otherwise reduce coverage shall not reduce or void the coverage as to any insured, shall afford
coverage for claims based on acts, omissions, injury or damage which occurred or arose (or the onset of which occurred or arose in whole or in part during the policy period), and shall provide that Landlord will receive thirty
(30) days’ written notice from the insurer prior to any cancellation or material change of coverage; 
 (b)
commercial property insurance, including sprinkler leakages, vandalism and malicious mischief and plate glass damage covering all the items specified as Tenant’s Property and all other property of every description including
stock-in-trade, furniture, fittings, installations, alterations, additions, partitions and fixtures or anything in the nature of a leasehold improvement made or installed by or on behalf of the Tenant in the Premises in an amount of not less than
one hundred percent (100%) of the full replacement cost thereof as shall from time to time be determined by Tenant in form reasonably satisfactory to Landlord; 

(c) Worker’s Compensation Insurance in the amounts and coverages required under worker’s compensation, disability and
similar employee benefit laws applicable to Tenant and/or the Premises from time to time, and Employer’s Liability Insurance, with limits of not less than one million dollars ($1,000,000) or such higher amounts as may be required by law; 

(d) business income insurance with extra expense insurance in an amount sufficient to insure payment of Rent for a period of not less
than twelve (12) months during any interruption of Tenant’s business by reason of the Premises or Tenant’s Property being damaged by casualty; and 

(e) any other form or forms of insurance as Landlord may reasonably require from time to time in amounts and for insurable risks
against which a prudent tenant would protect itself to the extent landlords of comparable buildings in the vicinity of the in the Property require their tenants to carry such other form(s) of insurance. 

13.3. Policies. All policies of insurance required of Tenant shall be issued by insurance companies with general policyholders’
rating of not less than A, as rated in the most current available “Best’s Insurance Reports,” and not prohibited from doing business in the 

 
State of California, and shall, with the exception of Workers Compensation Insurance, include as additional insureds Landlord, and such other persons or entities as Landlord specifies from time
to time. Such policies, with the exception of Worker’s Compensation Insurance, shall be for the mutual and joint benefit and protection of Landlord, Tenant and others specified by Landlord. Executed copies of Tenant’s policies of insurance
or certificates thereof shall be delivered to Landlord within ten (10) days prior to the delivery of possession of the Premises to Tenant and thereafter within thirty (30) days prior to the expiration of the term of each such policy. All
commercial general liability and property damage policies shall contain a provision that Landlord and any other additional insured, although named as additional insureds, shall nevertheless be entitled to recover under said policies for a covered
loss occasioned by it, its servants, agents and employees, by reason of Tenant’s negligence. As often as any policy shall expire or terminate, renewal or additional policies shall be procured and maintained by Tenant in like manner and to like
extent. All such policies of insurance shall provide that the company writing said policy will give to Landlord thirty (30) days notice in writing in advance of any cancellation or lapse or of the effective date of any reduction in the amounts
of insurance. All commercial general liability, property damage and other casualty policies shall be written on an occurrence basis. Landlord’s coverage shall not be contributory. No policy shall have a deductible in excess of $5,000 for any
one occurrence. 
 13.4. Landlord’s Rights. Should Tenant fail to take out and keep in force each insurance policy required
under this Article 13, or should such insurance not be approved by Landlord and should the Tenant not rectify the situation within two (2) Business Days after written notice from Landlord to Tenant, Landlord shall have the right, without
assuming any obligation in connection therewith, to purchase such insurance at the sole cost of Tenant, and all costs incurred by Landlord shall be payable to Landlord by Tenant within thirty (30) days after demand as Additional Rent and
without prejudice to any other rights and remedies of Landlord under this Lease. 
 13.5. Waiver of Subrogation. Notwithstanding
anything to the contrary contained herein, to the extent permitted by their respective policies of insurance and to the extent of insurance proceeds received (or which would have been received had the party carried the insurance required by this
Lease) with respect to the loss, Landlord and Tenant each hereby waive any right of recovery against the other party and against any other party maintaining a policy of insurance with respect to the Property or any portion thereof or the contents of
the Premises or the Building for any loss or damage sustained by such other party with respect to the Premises, the Building or the Property, or any portion thereof, or the contents of the same or any operation therein, whether or not such loss is
caused by the fault or negligence of such other party. Either party shall notify the other party if the policy of insurance carried by it does not permit the foregoing waiver. 

13.6. No Liability. No approval by Landlord of any insurer, or the terms or conditions of any policy, or any coverage or amount of
insurance, or any deductible amount shall be construed as a representation by Landlord of the solvency of the insurer or the sufficiency of any policy or any coverage or amount of insurance or deductible and Tenant assumes full risk and
responsibility for any inadequacy of insurance coverage or any failure of insurers. 
 14. ASSIGNMENT AND SUBLETTING 

14.1. Consent Required. Tenant shall not directly or indirectly, voluntarily or by operation of law, sell, assign, encumber, pledge or
otherwise transfer or hypothecate all or 

 
any part of its interest in or rights with respect to the Premises or its leasehold estate (collectively, “Assignment”), or permit all or any portion of the Premises to be
occupied by anyone other than itself or sublet all or any portion of the Premises (collectively, “Sublease”) without Landlord’s prior written consent, such consent not to be unreasonably withheld (subject to
Landlord’s rights as described in Sections 14.5). Landlord and Tenant acknowledge that it shall be reasonable for Landlord to withhold its consent in the following instances: 

(a) the use of the Premises would not comply with the provisions of this Lease; 

(b) Tenant is in default of any obligation of Tenant under this Lease, or Tenant has defaulted under this Lease on two or more
occasions within the prior year; 
 (c) the assignment or sublease is for a portion of the Premises or would result in the dividing
or sub-demising of the Premises; 
 (d) the proposed assignee or sublessee is a governmental agency; 

(e) in Landlord’s reasonable judgment, the use of the Premises by the proposed assignee or sublessee would involve occupancy by
other than for a Permitted Use, would entail any alterations which would lessen the value of the leasehold improvements in the Premises, or would require increased services by Landlord; 

(f) in Landlord’s reasonable judgment, the financial worth of the proposed assignee or sublessee does not meet the credit
standards applied by Landlord; 
 (g) the proposed assignee or sublessee (or any of its affiliates) has been in material default
under a lease, has been in litigation with a previous landlord, or in the ten years prior to the assignment or sublease has filed for bankruptcy protection, has been the subject of an involuntary bankruptcy, or has been adjudged insolvent; 

(h) Landlord has experienced a previous default by or is in litigation with the proposed assignee or sublessee; 

(i) in Landlord’s reasonable judgment, the Premises or any part of the Building, will be used in a manner that will violate any
negative covenant as to use contained in this Lease; the use of the Premises by the proposed assignee or sublessee will violate any applicable law, ordinance, or regulation; 

(j) the proposed assignee or sublessee is a tenant in the Building or 2000 Sierra Point Parkway, Brisbane, either as of the date of
this Lease or at the time of Notice, or has within the prior three (3) months been offered to Lease other office space in the Building or 2000 Sierra Point Parkway, Brisbane, by Landlord; or 

(k) the proposed assignment or sublease fails to include all of the terms and provisions required to be included therein pursuant to
this Article 14. 
 14.2. Notice. If Tenant desires to enter into a Sublease of all or any portion of the Premises or Assignment of
this Lease (except as provided in Section 14.7), it shall give written notice (the “Transfer Notice”) to Landlord of its intention to do so, which notice shall contain (a) the name and address of the proposed
assignee, subtenant or occupant (the 

 
“Transferee”), (b) the nature of the proposed Transferee’s business to be carried on in the Premises, (c) the terms and provisions of the proposed
Assignment or Sublease, and (d) such financial information as Landlord may reasonably request concerning the proposed Transferee (hereafter the “Complete Transfer Notice”). 

14.3. Terms of Approval. Landlord shall endeavor to respond to Tenant’s request for approval within fifteen (15) days after
receipt of the Complete Transfer Notice; however, Landlord’s failure to respond shall not result in a deemed approval. If Landlord approves the proposed Assignment or Sublease, Tenant may, not later than thirty (30) days thereafter, enter
into the Assignment or Sublease with the proposed Transferee upon the terms and conditions set forth in the Transfer Notice. 
 14.4.
Excess Rent. For any Assignment or Sublease (other than a Permitted Transfer under Section 14.7), fifty percent (50%) of the Excess Rent received by Tenant shall be paid to Landlord as and when received by Tenant. “Excess
Rent” means the gross revenue received from the Transferee during the Sublease term or with respect to the Assignment, less (a) the gross revenue received by Landlord from Tenant during the period of the Sublease term or
concurrently with or after the Assignment; (b) any reasonably documented tenant improvement allowance or other economic concession (planning allowance, moving expenses, etc.), paid by Tenant to or on behalf of the Transferee; (d) customary
and reasonable external brokers’ commissions to the extent paid and documented; (e) reasonable attorneys’ fees; and (f) reasonable costs of advertising the space for Sublease or Assignment (collectively, “Transfer
Costs”). Tenant shall not be required to pay to Landlord any Excess Rent until Tenant has recovered its Transfer Costs. 

14.5. Landlord Right of First Refusal. Except for Permitted Transfers, Tenant’s Transfer Notice shall also include a written offer
that includes all of the substantial business terms that Tenant has offered to a Transferee and shall offer to Transfer to Landlord, Tenant’s interest in the portion of the Premises offered to the Transferee on such terms and conditions (the
“Offer”). Landlord shall have fifteen (15) days from Landlord’s receipt of the Offer to accept the Offer by written notice to Tenant or to approve or disapprove the Transfer as provided in Section 14.3. If
Landlord accepts the Offer, Landlord and Tenant shall consummate the Transfer within fifteen (15) days after Landlord’s written notice of acceptance. The Transfer shall be consummated by Tenant’s delivery to Landlord of a good and
sufficient assignment of lease or sublease, which shall grant Landlord the right to re-lease the Premises to new tenants on a direct basis. If Landlord does not accept the Offer, but approves the Transfer, then in the event the terms of the Transfer
are materially changed during subsequent negotiations to be more favorable to the Transferee, Tenant shall again deliver to Landlord an Offer in accordance with this Section, offering the interest to Landlord on such more favorable terms. Landlord
shall then have another period of fifteen (15) days after receipt of such Offer to accept such Offer. 
 14.6. No Release. No
Sublease or Assignment by Tenant nor any consent by Landlord thereto shall relieve Tenant of any obligation to be performed by Tenant under this Lease. Any Sublease or Assignment that is not in compliance with this Article shall be null and void
and, at the option of Landlord, shall constitute an Event of Default by Tenant under this Lease, and Landlord shall be entitled to pursue any right or remedy available to Landlord under the terms of this Lease or under the laws of the State of
California. The acceptance of any Rent or other payments by Landlord from a proposed Transferee shall not constitute consent to such Sublease or Assignment by Landlord or a recognition of any Transferee, or a waiver by Landlord of any failure of
Tenant or other Transferor to comply with this Article. 

 14.7. Permitted Transfers. Notwithstanding anything in this Article 14 to the contrary,
but subject to the provisions of Section 14.8 below, Landlord’s prior written consent shall not be required for any assignment of this Lease or sublease to any of the following (each a “Permitted Transferee”):
(a) a successor entity related to Tenant by merger, consolidation, or non-bankruptcy reorganization, or (b) a transferee of substantially all of Tenant’s assets (collectively, “Permitted Transfers”); provided
that after such assignment or transfer the operation of the business conducted in the Premises shall be in the manner required by this Lease and the Transferee shall have a net worth and credit quality equal to the greater of the Tenant’s net
worth and credit quality at the Commencement Date or the net worth and credit quality of the Tenant immediately prior to the consummation of the Assignment or sublease. 

14.8. Assumption of Obligations. Any Transferee shall, from and after the effective date of the Assignment, assume all obligations of
Tenant under this Lease with respect to the Transferred Space and shall be and remain liable jointly and severally with Tenant for the payment of Base Rent and Additional Rent, and for the performance of all of the terms, covenants, conditions and
agreements herein contained on Tenant’s part to be performed for the Term. No Assignment shall be binding on Landlord unless Tenant delivers to Landlord a counterpart of the Assignment and an instrument that contains a covenant of assumption
reasonably satisfactory in substance and form to Landlord, and consistent with the requirements of this Section. 
 14.9. Landlord’s
Costs. Tenant shall reimburse Landlord for its reasonable third-party costs (including, without limitation, the fees of Landlord’s counsel), incurred in connection with Landlord’s review and processing of documents regarding any
proposed assignment or sublease. 
 15. DEFAULT 

15.1. Event of Default. The occurrence of any of the following shall be an “Event of Default”
on the part of Tenant: 
 (a) Failure to pay any part of the Base Rent or Additional Rent, or any other sums of money that
Tenant is required to pay under this Lease where such failure continues for a period of three (3) Business Days after written notice of default from Landlord to Tenant. Landlord’s notice to Tenant pursuant to this subsection shall be
deemed to be the notice required under California Code of Civil Procedure Section 1161. 
 (b) Failure to perform any other
covenant, condition or requirement of this Lease when such failure shall continue for a period of thirty (30) days after written notice thereof from Landlord to Tenant; provided that if the nature of the default is such that more than thirty
(30) days are reasonably required for its cure, then an Event of Default shall not be deemed to have occurred if Tenant shall commence such cure within said thirty (30) day period and thereafter diligently and continuously prosecute such
cure to completion. Landlord’s notice to Tenant pursuant to this subsection shall be deemed to be the notice required under California Code of Civil Procedure Section 1161. 

(c) The abandonment or vacating for more than one (1) month of the Premises by Tenant. 

(d) Tenant shall admit in writing its inability to pay its debts generally as they become due, file a petition in bankruptcy,
insolvency, reorganization, dissolution or 

 liquidation under any law or statute of any government or any subdivision thereof either now or hereafter in
effect, or Tenant shall make an assignment for the benefit of its creditors, consent to or acquiesce in the appointment of a receiver of itself or of the whole or any substantial part of the Premises. 

(e) A court of competent jurisdiction shall enter an order, judgment or decree appointing a receiver of Tenant or of the whole or any
substantial part of the Premises and such order, judgment or decree shall not be vacated, set aside or stayed within thirty (30) days after the date of entry of such order, judgment, or decree, or a stay thereof shall be thereafter set aside.

 (f) A court of competent jurisdiction shall enter an order, judgment or decree approving a petition filed against Tenant under
any bankruptcy, insolvency, reorganization, dissolution or liquidation law or statute of the federal or state government or any subdivision of either now or hereafter in effect, and such order, judgment or decree shall not be vacated, set aside or
stayed within thirty (30) days from the date of entry of such order, judgment or decree, or a stay thereof shall be thereafter set aside. 

15.2. Remedies. Upon the occurrence of an Event of Default, Landlord shall have the following rights and remedies: 

(a) The right to terminate this Lease upon written notice to Tenant, in which event Tenant shall immediately surrender possession of
the Premises in accordance with Article 20. 
 (b) The right to bring a summary action for possession of the Premises. 

(c) The rights and remedies described in California Civil Code Section 1951.2, pursuant to which Landlord may recover from Tenant upon
a termination of the Lease, (i) the worth at the time of award of the unpaid rent which has been earned at the time of termination; (ii) the worth at the time of award of the amount by which the unpaid rent which would have been earned after
termination until the time of award exceeds the amount of such rental loss that Tenant proves could have been reasonably avoided; (iii) the worth at the time of the award of the amount by which the unpaid rent for the balance of the term after
the time of award exceeds the amount of such rental loss that Tenant proves could be reasonably avoided; and (iv) any other amount necessary to compensate Landlord for all the detriment proximately caused by Tenant’s failure to perform its
obligations under this Lease or which in the ordinary course of events would be likely to result therefrom. The “worth at the time of award” of the amounts referred to in (i) and (ii) above is computed by allowing interest at the
rate of ten percent (10%) per annum. The “worth at the time of award” of the amount referred to in (iii) above shall be computed by discounting such amount at the discount rate of the Federal Reserve Bank of San Francisco at the
time of award plus one percent (1%). The detriment proximately caused by Tenant’s failure to perform its obligations under this Lease or which in the ordinary course of events would be likely to result therefrom includes, without limitation,
(1) the unamortized portion of any brokerage or real estate agent’s commissions paid in connection with the execution of this Lease, (2) any direct costs or expenses incurred by Landlord in recovering possession of the Premises,
maintaining or preserving the Premises after such default, (3) preparing the Premises for reletting to a new tenant, (4) any repairs or alterations to the Premises for such reletting, (5) leasing commissions, architect’s fees and
any other costs necessary or appropriate either to relet the Premises or, if reasonably necessary in order to relet 

 
the Premises, to adapt them to another beneficial use by Landlord and (6) such amounts in addition to or in lieu of the foregoing as may be permitted from time to time by Applicable Laws to
the extent that such payment would not result in a duplicative recovery. 
 (d) The rights and remedies described in California
Civil Code Section 1951.4 which allow Landlord to continue this Lease in effect and to enforce all of Landlord’s rights and remedies under this Lease, including the right to recover Base Rent, Additional Rent and other charges payable hereunder
as they become due. Acts of maintenance or preservation, efforts to relet the Premises or the appointment of a receiver upon Landlord’s initiative to protect its interest under this Lease shall not constitute a termination of Tenant’s
right to possession. 
 (e) The right and power, as attorney-in-fact for Tenant, to sublet the Premises, to collect rents from all
subtenants and to provide or arrange for the provision of all services and fulfill all obligations of Tenant under any permitted subleases. Landlord is hereby authorized on behalf of Tenant, but shall have absolutely no obligation, to provide such
services and fulfill such obligations and to incur all such expenses and costs as Landlord deems necessary. Landlord is hereby authorized, but not obligated, to relet the Premises or any part thereof on behalf of Tenant, to incur such expenses as
may be necessary to effect a relet and make said relet for such term or terms, upon such conditions and at such rental as Landlord in its reasonable discretion may deem proper. Tenant shall be liable immediately to Landlord for all costs and
expenses Landlord incurs in reletting the Premises including, without limitation, brokers’ commissions, expenses of remodeling the Premises required by the reletting, and the cost of collecting rents and fulfilling the obligations of Tenant to
any subtenant. If Landlord relets the Premises or any portion thereof, such reletting shall not relieve Tenant of any obligation hereunder, except that Landlord shall apply the rent or other proceeds actually collected by it as a result of such
reletting against any amounts due from Tenant hereunder to the extent that such rent or other proceeds compensate Landlord for the nonperformance of any obligation of Tenant hereunder. Such payments by Tenant shall be due at such times as are
provided elsewhere in this Lease, and Landlord need not wait until the termination of this Lease, by expiration of the Term or otherwise, to recover them by legal action or in any other manner. Landlord may execute any sublease made pursuant to this
Section in its own name, and the tenant thereunder shall be under no obligation to see to the application by Landlord of any rent or other proceeds, nor shall Tenant have any right to collect any such rent or other proceeds. Landlord shall not by
any reentry or other act be deemed to have accepted any surrender by Tenant of the Premises or Tenant’s interest therein, or be deemed to have otherwise terminated this Lease, or to have relieved Tenant of any obligation hereunder, unless
Landlord shall have given Tenant express written notice of Landlord’s election to do so as set forth herein. 
 (f) The right
to enjoin, and any other remedy or right now or hereafter available to a Landlord against a defaulting tenant under the laws of the State of California or the equitable powers of its courts, and not otherwise specifically reserved herein. 

(g) If this Lease provides for a postponement of deferral of any Rent, or for commencement of payment of Rent to a date later than the
Commencement Date, or for a period of “free” Rent or any other Rent concession (collectively, “Abated Rent”), the right upon an Event of Default to demand immediate payment of the value of the Abated Rent. 

15.3. Cumulative Remedies. The various rights and remedies reserved to Landlord, including those not specifically described herein,
shall, to the extent that the exercise of such right and/or remedy does not result in a duplicative recovery, be cumulative and shall 

 
be in addition to every other right or remedy provided for in this Lease or now or hereafter existing at law or in equity and the exercise of the rights or remedies provided for in this Lease or
now or hereafter existing at law or in equity shall not preclude the simultaneous or later exercise by Landlord of any or all other rights and remedies. 

15.4. Waiver of Redemption by Tenant. Tenant hereby waives any right to relief against forfeiture of this Lease pursuant to California
Code of Civil Procedure Section 1179. 
 15.5. Landlord’s Right to Cure. If Tenant shall fail or neglect to do or perform
any covenant or condition required under this Lease and such failure shall not be cured within any applicable grace period, Landlord may, on five (5) days notice to Tenant, but shall not be required to, make any payment payable by Tenant
hereunder, discharge any lien, take out, pay for and maintain any insurance required hereunder, or do or perform or cause to be done or performed any such other act or thing (entering upon the Premises for such purposes, if Landlord shall so elect),
and Landlord shall not be or be held liable or in any way responsible for any loss, disturbance, inconvenience, annoyance or damage resulting to Tenant on account thereof. Tenant shall repay to Landlord within fifteen (15) days after demand the
entire out-of-pocket cost and expense incurred by Landlord in connection with the cure, including, without limitation, compensation to the agents, consultants and contractors of Landlord and reasonable
attorneys’ fees and expenses. Landlord may act upon shorter notice or no notice at all if necessary in Landlord’s reasonable judgment to meet an emergency situation or governmental or municipal time limitation or to protect Landlord’s
interest in the Premises. Landlord shall not be required to inquire into the correctness of the amount of validity or any tax or lien that may be paid by Landlord and Landlord shall be duly protected in paying the amount of any such tax or lien
claimed and in such event Landlord also shall have the full authority, in Landlord’s sole judgment and discretion and without prior notice to or approval by Tenant, to settle or compromise any such lien or tax. Any act or thing done by Landlord
pursuant to the provisions of this Section shall not be or be construed as a waiver of any such failure by Tenant, or as a waiver of any term, covenant, agreement or condition herein contained or of the performance thereof. 

15.6. Landlord’s Default. Landlord shall be in default under this Lease if Landlord fails to perform obligations required of
Landlord within thirty (30) days after written notice by Tenant to Landlord and to the holder of any first mortgage or deed of trust covering the Premises whose name and address shall have heretofore been furnished to Tenant in writing,
specifying wherein Landlord has failed to perform such obligations; provided, however, that if the nature of Landlord’s obligations is such that more than thirty (30) days are required for performance, then Landlord shall not be in default
if Landlord commences performance within such thirty (30) day period and thereafter diligently prosecutes the same to completion. Tenant shall be entitled to actual (but not consequential) damages in the event of an uncured default by Landlord,
but the provisions of Article 17 shall apply to any Landlord default and Tenant shall not have the right to terminate this Lease as a result of a Landlord default. 

16. LANDLORD’S RESERVED RIGHTS 

16.1. Control of Common Area. Landlord reserves the right, at any time and from time to time, to make alterations, additions, repairs,
replacements or improvements to all or any part of the Building (including the Building Structure and Building Systems), the Common Area and the Property. Landlord may make changes at any time and from time to time in the size, shape, location, use
and extent of the Common Area, and no such change shall entitle 

 
Tenant to any abatement of rent or damages. Landlord shall at all times during the Term have the sole and exclusive control of the Building Structure and the Common Area, and may at any time and
from time to time during the Term restrain any use or occupancy of the Common Area except as authorized by this Lease. With respect to those specific Common Areas provided inside 2000 Sierra Point Parkway, the office building adjacent to the
Building, Landlord reserves the right to alter, reconfigure, replace, diminish, expand, cease access to, or remove all or any part. Landlord may temporarily or permanently close any portion of the Common Area for repairs, maintenance, replacements
or alterations, to prevent a dedication or the accrual of prescriptive rights, or for any other reasonable purpose; provided, however, that Landlord shall use reasonable efforts not to materially adversely affect Tenant’s use of the Premises.
Tenant’s rights in and to the Common Area shall at all times be subject to the rights of Landlord and Tenant shall keep the Common Area free and clear of any obstructions created or permitted by Tenant or resulting from Tenant’s
operations. 
 16.2. Access. Landlord reserves (for itself and its agents, consultants, contractors and employees) the right to enter
the Premises at all reasonable times and, except in cases of emergency, after giving Tenant reasonable notice, to inspect the Premises (including, without limitation, environmental testing); to supply any service to be provided by Landlord
hereunder; to show the Premises to prospective purchasers or mortgagees; to show the Premises to prospective tenants during the last year of the Term; to post notices of non-responsibility; and to repair or
maintain the Premises and the Building as required or permitted by the terms of this Lease, without abatement of Rent, and may for that purpose erect, use and maintain necessary structures in and through the Premises and the Building where
reasonably required by the character of the work to be performed. Tenant hereby waives any claim for damages for any injury or inconvenience to or interference with Tenant’s business, any loss of occupancy or quiet enjoyment of the Premises or
any other loss occasioned thereby, except to the extent caused by the gross negligence or willful misconduct of Landlord in the exercise of its rights and provided that Landlord shall use reasonable efforts not to materially adversely affect
Tenant’s use of the Premises. All locks for all of the doors in, upon and about the Premises, excluding Tenant’s vaults and safes or special security areas (designated in advance in writing by Tenant) shall at all times be keyed to a
master system and Landlord shall at all times have and retain a key with which to unlock all of said doors. Landlord shall have the right to use any and all means that Landlord may deem necessary or proper to open said doors in an emergency in order
to obtain entry to any portion of the Premises, and any such entry to the Premises or portions thereof obtained by Landlord by any of said means, or otherwise, shall not under any circumstances be construed or deemed to be a forcible or unlawful
entry into, or a detainer of, the Premises, or an eviction, actual or constructive, of Tenant from the Premises or any portion thereof. 

16.3. Easements. Landlord reserves the right to grant or relocate all easements and rights of way which Landlord in its sole discretion
may deem necessary or appropriate; provided that Tenant’s rights to use the Property is not materially impeded. 
 16.4. Use of
Additional Areas. Landlord reserves the exclusive right to use any air space above the Property, and the land beneath the Premises; provided that such use shall not materially impede Tenant’s use of and access to the Premises. 

16.5. Subordination. This Lease shall be subject and subordinate at all times to: (a) all reciprocal easement agreements, and any
ground leases or underlying leases which may now exist or hereafter be executed affecting the Property, and (b) the lien of any mortgage or deed of trust which may now exist or hereafter be executed in any amount for which the

 
Property, or any ground leases or underlying leases, or Landlord’s interest or estate in any of said items, is specified as security. Notwithstanding the foregoing, Landlord shall have the
right to subordinate or cause to be subordinated to this Lease any of the items referred to in clause (a) or (b) above, subject to compliance with the condition precedent set forth below. In the event that any ground lease or underlying lease
terminates for any reason or any mortgage or deed of trust is foreclosed or a conveyance in lieu of foreclosure is made for any reason, (i) no person or entity which as a result of the foregoing succeeds to the interest of Landlord under this
Lease (a “Successor”) shall be liable for any default by Landlord or any other matter that occurred prior to the date the Successor succeeded to Landlord’s interest in this Lease, and (ii) Tenant shall,
notwithstanding any subordination, attorn to and become the tenant of the Successor, at the option of the Successor. Tenant covenants and agrees, however, to execute and deliver, upon demand by Landlord and in the form reasonably requested by
Landlord, any additional documents evidencing the priority or subordination of this Lease with respect to any such ground leases, underlying leases, reciprocal easement agreements or similar documents or instruments, or with respect to the lien of
any such mortgage or deed of trust and Tenant’s failure to execute and deliver any such document within fifteen (15) days after such demand by Landlord shall constitute an Event of Default without further notice. 

17. LIMITATION OF LANDLORD’S LIABILITY 

17.1. Limitation. Landlord shall not be responsible for or liable to Tenant and Tenant hereby releases Landlord, waives all claims
against Landlord and assumes the risk for any injury, loss or damage to any person or property in or about the Property by or from any cause whatsoever (other than Landlord’s gross negligence or willful misconduct) including, without
limitation, (a) acts or omissions of persons occupying adjoining premises, (b) theft or vandalism, (c) burst, stopped or leaking water, gas, sewer or steam pipes, (d) loss of utility service, (e) accident, fire or casualty,
(f) nuisance, and (g) work done by Landlord in the Property. There shall be no abatement of Rent and no liability of Landlord by reason of any injury to or interference with Tenant’s business arising from the making of any repairs,
alterations or improvements to any portion of the Property or to fixtures, appurtenances and equipment in the Property; provided, however, that in the event Landlord fails to perform its obligations to make repairs, alterations or improvements or
performs such obligations in a negligent manner in each case which results in Tenant being unable to operate its business at the Premises for a period of more than five (5) consecutive Business Days, then Tenant shall be entitled to an
abatement of Rent commencing on the sixth business day Tenant is unable to operate and continuing until the Premises are again available for operation of Tenant’s business. Such Rent abatement shall be Tenant’s only remedy in the event of
a negligent interference with Tenant’s business and Tenant shall not be entitled to damages or to termination of this Lease arising from Landlord’s repairs, alterations or improvements. No interference with Tenant’s operations in the
Premises shall constitute a constructive or other eviction of Tenant. Tenant hereby waives and releases any right it may have to make repairs at Landlord’s expense under Sections 1941 and 1942 of the California Civil Code, or under any similar
law, statute or ordinance now or hereafter in effect. 
 17.2. Sale of Property. It is agreed that Landlord may at any time sell,
assign or transfer its interest as landlord in and to this Lease, and may at any time sell, assign or transfer its interest in and to the Property. In the event of any transfer of Landlord’s interest in this Lease or in the Property, the
transferor shall be automatically relieved of any and all of Landlord’s obligations and liabilities accruing from and after the date of such transfer; provided 

 
that the transferee assumes all of Landlord’s obligations under this Lease. Tenant hereby agrees to attorn to Landlord’s assignee, transferee, or purchaser from and after the date of
notice to Tenant of such assignment, transfer or sale, in the same manner and with the same force and effect as though this Lease were made in the first instance by and between Tenant and the assignee, transferee or purchaser. 

17.3. No Personal Liability. In the event of any default by Landlord hereunder, Tenant shall look only to Landlord’s interest in
the Property and rents therefrom and any available insurance proceeds for the satisfaction of Tenant’s remedies, and no other property or assets of Landlord or any trustee, partner, member, officer or director thereof, disclosed or undisclosed,
shall be subject to levy, execution or other enforcement procedure for the satisfaction of Tenant’s remedies under or with respect to this Lease. 

18. DESTRUCTION 

18.1. Landlord’s Repair Obligation. If the Property or any portion thereof is damaged by fire or other casualty, Landlord shall
repair the same (including the Tenant Improvement Work, but not any Tenant’s Alterations); provided that (a) such repairs can be made under the laws and regulations of the federal, state and local governmental authorities having
jurisdiction within twelve (12) months after the date of such damage (or in the case of damage occurring during the last twelve (12) months of the Term, provided that such repairs can be made within ninety (90) days after the date of
such damage), (b) such repairs are fully covered (except for any deductible) by the proceeds of insurance maintained by Landlord, and (c) the damage does not affect more than fifty percent (50%) of the assessed value of the Building. 

18.2. Notice. Landlord shall notify Tenant within sixty (60) days after the date of damage whether or not the requirements for
reconstruction and repair described in Section 18.1 are met. If such requirements are not met, Landlord shall have the option, exercisable within sixty (60) days after the date of such damage either to: (a) notify Tenant of Landlord’s
intention to repair such damage, in which event this Lease shall continue in full force and effect (unless terminated by Tenant pursuant to Section 18.3 below), or (b) notify Tenant of Landlord’s election to terminate this Lease as of
the date of the damage. If such notice to terminate is given by Landlord, this Lease shall terminate as of the date of such damage. If within ten (10) days after receipt of a notice from Landlord electing to terminate this Lease because of the
unavailability of insurance proceeds, Tenant sends Landlord a notice electing to reimburse Landlord for the cost of such repairs that are in excess of five percent (5%) of the replacement cost of the Building (as determined as of the day prior
to any such damage), this Lease shall not terminate, and Landlord shall complete such repairs. 
 18.3. Termination by Tenant. If
Landlord elects to repair or is required to repair the damage and any such repair (a) is not commenced by Landlord within one hundred twenty (120) days after the occurrence of such damage or destruction, or (b) is not or cannot
practicably be substantially completed by Landlord within twelve (12) months after the occurrence of such damage or destruction (or in the case of damage occurring in the last twelve (12) months of the Term, within ninety (90) days),
then in either such event Tenant may, at its option, upon written notice to Landlord to be delivered within fifteen (15) days after receipt of Landlord’s notice or the expiration of the 120-day commencement period, elect to terminate this
Lease as of the date of the occurrence of such damage or destruction. 

 18.4. Rent Adjustment. In case of termination pursuant to Sections 18.2 or 18.3 above, the
Base Rent and Operating Expenses shall be reduced by a proportionate amount based upon the extent to which such damage interfered with the business carried on by Tenant in the Premises, and Tenant shall pay such reduced Base Rent and Operating
Expenses up to the date of vacation of the Premises. If Landlord is required or elects to make repairs, and Tenant does not terminate this Lease pursuant to Section 18.3, this Lease shall remain in full force and effect except that Tenant shall
be entitled to a proportionate reduction of Base Rent and Operating Expenses from the date of such casualty and during the period such repairs are being made by a proportionate amount based upon the extent of interference with Tenant’s
operations in the Premises. The full amount of Base Rent and Operating Expenses shall again become payable immediately upon the completion of such work of repair, reconstruction or restoration. The repairs to be made by Landlord under this Article
shall not include, and Landlord shall not be required to repair, any casualty damage to Tenant’s Property or any Alterations. 

18.5. Tenant Obligations. If Landlord elects or is required to repair, reconstruct or restore the Premises after any damage or
destruction, Tenant shall be responsible at its own expense for the repair and replacement of any of Tenant’s Property and any Alterations that Tenant elects to replace. 

18.6. No Claim. Tenant shall have no interest in or claim to any portion of the proceeds of any property insurance or self-insurance
maintained by Landlord in connection with the damage. If Landlord is entitled and elects not to rebuild the Premises, Landlord shall relinquish to Tenant such claim as Landlord may have for any part of the proceeds of any insurance maintained by
Tenant under Section 13.2 of this Lease. 
 18.7. No Damages. If Landlord is required or elects to make any repairs,
reconstruction or restoration of any damage or destruction to the Premises under any of the provisions of this Article 18, Tenant shall not be entitled to any damages by reason of any inconvenience or loss sustained by Tenant as a result thereof.
Except as expressly provided in Section 18.4, there shall be no reduction, change or abatement of any rental or other charge payable by Tenant to Landlord hereunder, or in the method of computing, accounting for or paying the same. Tenant
hereby waives the provisions of Section 1932(2) and Section 1933(4) of the California Civil Code, or any other statute or law that may be in effect at the time of a casualty under which a lease is automatically terminated or a tenant is
given the right to terminate a lease due to a casualty. 
 19. EMINENT DOMAIN 

19.1. Taking. If all or any part of the Premises shall be taken as a result of the exercise of the power of eminent domain or any
transfer in lieu thereof, this Lease shall terminate as to the part so taken as of the date of taking or as of the date of final judgment, whichever is earlier, and, in the case of a partial taking of at least twenty-five percent (25%) of the
Rentable Area of the Premises, either Landlord or Tenant shall have the right to terminate this Lease as to the balance of the Premises by written notice to the other within thirty (30) days after such date, provided, however, that a condition
to the exercise by Tenant of such right to terminate shall be that the portion of the Premises taken shall be of such extent and nature as substantially to handicap, impede or impair Tenant’s use of the balance of the Premises. If any material
part of the Common Area shall be taken as a result of the exercise of the power of eminent domain or any transfer in lieu thereof, whether or not the Premises are affected, Landlord shall have the right to terminate this Lease by written notice to
Tenant within thirty (30) 

 
days of the date of taking. If any material part of the Common Area shall be taken as a result of the exercise of the power of eminent domain or any transfer in lieu thereof, such that
Tenant’s access to or use of the Premises is materially adversely affected, Tenant shall have the right to terminate this Lease by written notice to Landlord within thirty (30) days of the date of taking. 

19.2. Award. In the event of any taking, Landlord shall be entitled to any and all compensation, damages, income, rent, awards, or any
interest therein whatsoever which may be paid or made in connection therewith, and Tenant shall assign to Landlord any right to compensation or damages for the condemnation of its leasehold interest; provided that Tenant may file a claim for
(a) Tenant’s relocation expenses, and (b) the taking of Tenant’s Property. 
 19.3. Partial Taking. In the event
of a partial taking of the Premises which does not result in a termination of this Lease, the Base Rent and Operating Expenses shall be adjusted as follows: 

(a) In the event of a partial taking, if this Lease is not terminated pursuant to this Article 19, Landlord shall repair, restore or
reconstruct the Premises to a useable state; provided that Landlord shall not be required to expend any sums other than those received pursuant to Section 19.2. 

(b) During the period between the date of the partial taking and the completion of any necessary repairs, reconstruction or
restoration, Tenant shall be entitled to a reduction of Base Rent and Operating Expenses by a proportionate amount based upon the extent of interference with Tenant’s operations in the Premises; and 

(c) Upon completion of said repairs, reconstruction or restoration, and thereafter throughout the remainder of the Term, the Base Rent
and Operating Expenses shall be recalculated based on the remaining total number of square feet of Rentable Area of the Premises. 

19.4. Temporary Taking. Notwithstanding any other provision of this Article, if a taking occurs with respect to all or any portion of
the Premises for a period of twelve (12) months or less, this Lease shall remain unaffected thereby and Tenant shall continue to pay Base Rent and Additional Rent and to perform all of the terms, conditions and covenants of this Lease, provided
that Tenant shall have the right to terminate this Lease if the taking continues beyond twelve (12) months. In the event of any such temporary taking, and if this Lease is not terminated, Tenant shall be entitled to receive that portion of any
award which represents compensation for the use or occupancy of the Premises during the Term up to the total Base Rent and Additional Rent owing by Tenant for the period of the taking, and Landlord shall be entitled to receive the balance of any
award. 
 19.5. Sale in Lieu of Condemnation. A voluntary sale by Landlord of all or any part of the Property to any public or
quasi-public body, agency or person, corporate or otherwise, having the power of eminent domain, either under threat of condemnation or while condemnation proceedings are pending, shall be deemed to be a taking under the power of eminent domain for
the purposes of this Article. 
 19.6. Waiver. Except as provided in this Article, Tenant hereby waives and releases any right it may
have under any Applicable Law to terminate this Lease as a result of a taking, including without limitation Sections 1265.120 and 1265.130 of the California Code of Civil Procedure, or any similar law, statute or ordinance now or hereafter in
effect. 

 20. SURRENDER 

20.1. Surrender. Upon the Termination Date, Tenant shall surrender the Premises to Landlord in as good order and repair as on the
Commencement Date, reasonable wear and tear and damage by casualty excepted, free and clear of all letting and occupancies and free of Hazardous Materials as required pursuant to Article 12. Subject to Article 9, upon any termination of this Lease
all improvements, except for Tenant’s Property, shall automatically and without further act by Landlord or Tenant, become the property of Landlord, free and clear of any claim or interest therein by Tenant, and without payment therefore by
Landlord. 
 20.2. Holding Over. Any holding over after the expiration of the Term with the consent of Landlord shall be construed to
automatically extend the Term on a month-to-month basis at a Base Rent equal to the greater of (a) one and one-half (1.5) times the then-current Base Rent, and (b) the Rent rate at which Landlord is then offering space in Building,
and shall otherwise be on the terms and conditions of this Lease to the extent applicable. Any holding over without Landlord’s consent shall entitle Landlord to exercise any or all of its remedies provided in Article 15, notwithstanding that
Landlord may elect to accept one or more payments of Base Rent and Operating Expenses from Tenant. 
 20.3. Quitclaim. At the
expiration or earlier termination of this Lease, Tenant shall execute, acknowledge and deliver to Landlord, within ten (10) days after written demand from Landlord to Tenant, any quitclaim deed or other document required by any reputable title
company, licensed to operate in the State of California, to remove the cloud or encumbrance created by this Lease from the Property. 

21. FINANCIAL STATEMENTS 

Tenant shall tender to Landlord within fifteen (15) days after receipt of a written request any information reasonably requested by
Landlord regarding the financial stability, credit worthiness or ability of Tenant to pay the Rent due under this Lease. Landlord shall be entitled to rely upon the information provided in determining whether or not to enter into this Lease or for
the purpose of any financing or other transaction subsequently undertaken by Landlord. Tenant hereby represents and warrants to Landlord the following: (a) that all documents provided by Tenant to Landlord in connection with the negotiation of
this Lease are true and correct copies of the originals, (b) Tenant has not withheld any information from Landlord that is material to Tenant’s credit worthiness, financial condition or ability to perform its obligations hereunder,
(c) all information supplied by Tenant to Landlord is true, correct and accurate, and (d) no part of the information supplied by Tenant to Landlord contains any misleading or fraudulent statements. A default under this Article shall be a
non-curable default by Tenant and Landlord shall be entitled to pursue any right or remedy available to Landlord under the terms of this Lease or available to Landlord under the laws of the State of California. Landlord shall a be entitled to
disclose Tenant’s financial information to (1) its agents, employees and consultants, (2) potential purchasers of an interest in the Property, and (3) lenders contemplating making a loan to the Landlord to be secured by the
Property, provided that such recipients are advised of the confidential nature of such information and agree to maintain such confidentiality. 

22. TENANT CERTIFICATES 

Tenant, at any time and from time to time within fifteen (15) days after receipt of written notice from Landlord, shall execute,
acknowledge and deliver to Landlord or to any party 

 
designated by Landlord (including prospective lenders, purchasers, ground lessees and others similarly situated), a certificate of Tenant stating, to the best of Tenant’s knowledge:
(a) that Tenant has accepted the Premises, (b) the Commencement Date, the Rent Commencement Date and Expiration Date of this Lease, (c) that this Lease is unmodified and in full force and effect (or, if there have been modifications,
that same is in full force and effect as modified and stating the modifications), (d) whether or not there are then existing any defenses against the enforcement of any of the obligations of Tenant under this Lease (and, if so, specifying
same), (e) whether or not there are then existing any defaults by Landlord in the performance of its obligations under this Lease (and, if so, specifying same), (f) the dates, if any, to which the Base Rent and Operating Expenses have been
paid, and (g) any other factual information relating to the rights and obligations under this Lease that may reasonably be required by any of such persons. Failure to deliver such certificate when due shall constitute an Event of Default. At
the request of Tenant, Landlord shall execute, acknowledge and deliver to Tenant a certificate with similar types of information and in the time period set forth above. Failure by either Landlord or Tenant to execute, acknowledge and deliver such
certificate shall be conclusive evidence that this Lease is in full force and effect and has not been modified except as may be represented by the requesting party. 

23. RULES AND REGULATIONS; SIGNS 

23.1. Rules and Regulations. Tenant shall faithfully observe and comply with all rules and regulations and all reasonable modifications
thereof and additions thereto from time to time put into effect by Landlord (the “Rules and Regulations”). Landlord shall not enforce such Rules and Regulations in an unreasonable or discriminatory manner. In the event of any
conflict between the terms of this Lease and the terms, covenants, agreements and conditions of the Rules and Regulations, this Lease shall control. 

23.2. Signs. Landlord shall enter Tenant’s name in the Building directory located in the main lobby of the Building and on the
monument signs at the entry to the Property. Tenant shall have the right to install signage adjacent to the entrance doors to Tenant’s Premises identifying Tenant, subject to Landlord’s reasonable consent. 

24. INABILITY TO PERFORM 

Except as provided in Section 18, if Landlord is unable to fulfill or is delayed in fulfilling any of Landlord’s obligations under
this Lease, by reason of acts of God, accidents, breakage, repairs, strikes, lockouts, other labor disputes, inability to obtain utilities or materials or by any other reason beyond Landlord’s reasonable control, then no such inability or delay
by Landlord shall constitute an actual or constructive eviction, in whole or in part, or entitle Tenant to any abatement or diminution of Base Rent or Additional Rent, or relieve Tenant from any of its obligations under this Lease, or impose any
liability upon Landlord or Landlord’s Agents by reason of inconvenience, annoyance, interruption, injury or loss to or interference with Tenant’s business or use and occupancy or quiet enjoyment of the Premises or any loss or damage
occasioned thereby. If Tenant is unable to fulfill or is delayed in fulfilling any of Tenant’s obligations under this Lease (other than the payment of Rent), by reason of acts of God, accidents, breakage, repairs, strikes, lockouts, other labor
disputes, inability to obtain utilities or materials or by any other reason beyond Tenant’s reasonable control, then such inability or delay by Tenant shall excuse the performance of Tenant for a period equal to the duration of such prevention,
delay or stoppage. Tenant hereby waives and releases any right to terminate this Lease under Section 1932(1) of the California Civil Code, or any similar law, statute or ordinance now or hereafter in effect. 

 25. NOTICES 

Notices or other communications given or required to be given under this Lease shall be effective only if rendered or given in writing, sent
by certified mail with a return receipt requested, or delivered in person or by reputable overnight courier (e.g., Federal Express, UPS, etc.): (a) to Tenant at Tenant’s address set forth in Article 1; or (b) to Landlord at
Landlord’s address set forth in Article 1; or (c) to such other address as either Landlord or Tenant may designate as its new address for such purpose by notice given to the other in accordance with the provisions of this Article. Any
such notice or other communication shall be deemed to have been rendered or given five (5) days after the date mailed, if sent by certified mail, or upon the date of delivery in person or by courier, or when delivery is attempted but refused.

 26. QUIET ENJOYMENT 

Landlord covenants that so long as an Event of Default by Tenant is not in existence, upon paying the Base Rent and Additional Rent and
performing all of its obligations under this Lease, Tenant shall peaceably and quietly enjoy the Premises, subject to the terms and provisions of this Lease. 

27. AUTHORITY 
 If Tenant
is a corporation, limited liability company or a partnership, Tenant represents and warrants as follows: Tenant is an entity as identified in Article 1, duly formed and validly existing and in good standing under the laws of the state of
organization specified in Article 1 and qualified to do business in the State of California. Tenant has the power, legal capacity and authority to enter into and perform its obligations under this Lease and no approval or consent of any person is
required in connection with the execution and performance hereof. The execution and performance of Tenant’s obligations under this Lease will not result in or constitute any default or event that would be, or with notice or the lapse of time
would be, a default, breach or violation of the organizational instruments governing Tenant or any agreement or any order or decree of any court or other governmental authority to which Tenant is a party or to which it is subject. Tenant has taken
all necessary action to authorize the execution, delivery and performance of this Lease and this Lease constitutes the legal, valid and binding obligation of Tenant. Upon Landlord’s request, Tenant shall provide Landlord with evidence
reasonably satisfactory to Landlord confirming the foregoing representations and warranties. 
 Landlord represents and warrants as follows: Landlord has
the power, legal capacity and authority to enter into and perform its obligations under this Lease and no approval or consent of any person is required in connection with the execution and performance hereof. The execution and performance of
Landlord’s obligations under this Lease will not result in or constitute any default or event that would be, or with notice or the lapse of time would be, a default, breach or violation of the organizational instruments governing Landlord or
any agreement or any order or decree of any court or other governmental authority to which Landlord is a party or to which it is subject. Landlord has taken all necessary action to authorize the execution, delivery and performance of this Lease and
this Lease constitutes the legal, valid and binding obligation of Landlord. 

 28. BROKERS 

Tenant and Landlord warrant that they have had dealings with only the real estate brokers or agents listed in Article 1 in connection with the
negotiation of this Lease and that they know of no other real estate broker or agent who is entitled to a commission in connection with this Lease. Landlord shall pay the brokerage commission earned in connection with this transaction pursuant to
separate agreement. Tenant and Landlord shall indemnify, defend and hold the other harmless from and against all liabilities arising from any other claims of brokerage commissions or finder’s fees based on Tenant’s or Landlord’s, as
applicable, dealings or contacts with brokers or agents other than those listed in Article 1. 
 29. MISCELLANEOUS 

29.1. Entire Agreement. This Lease, including the exhibits that are incorporated herein and made a part of this Lease, contains the
entire agreement between the parties and all prior negotiations and agreements are merged herein. Tenant hereby acknowledges that neither Landlord nor Landlord’s Agents have made any representations or warranties with respect to the Premises,
the Property, or this Lease except as expressly set forth herein, and no rights, easements or licenses are or shall be acquired by Tenant by implication or otherwise unless expressly set forth herein. 

29.2. No Waiver. No failure by Landlord or Tenant to insist upon the strict performance of any obligation of Tenant or Landlord under
this Lease or to exercise any right, power or remedy consequent upon a breach thereof, no acceptance of full or partial Base Rent or Additional Rent during the continuance of any such breach by Landlord, or payment of Base Rent or Additional Rent by
Tenant to Landlord, and no acceptance of the keys to or possession of the Premises prior to the expiration of the Term by any employee or agent of Landlord shall constitute a waiver of any such breach or of such term, covenant or condition or
operate as a surrender of this Lease. No waiver of any breach shall affect or alter this Lease, but each and every term, covenant and condition of this Lease shall continue in full force and effect with respect to any other then-existing or
subsequent breach thereof. The consent of Landlord or Tenant given in any instance under the terms of this Lease shall not relieve Tenant or Landlord, as applicable, of any obligation to secure the consent of the other in any other or future
instance under the terms of this Lease. 
 29.3. Modification. Neither this Lease nor any term or provisions hereof may be changed,
waived, discharged or terminated orally, and no breach thereof shall be waived, altered or modified, except by a written instrument signed by the party against which the enforcement of the change, waiver, discharge or termination is sought. 

29.4. Successors and Assigns. The terms, covenants and conditions contained in this Lease shall bind and inure to the benefit of
Landlord and Tenant and, except as otherwise provided or limited herein, their respective personal representatives and successors and assigns. 

29.5. Validity. If any provision of this Lease or the application thereof to any person, entity or circumstance shall, to any extent,
be invalid or unenforceable, the remainder of this Lease, or the application of such provision to persons, entities or circumstances other than those as to which it is invalid or unenforceable, shall not be affected thereby, and each provision of
this Lease shall be valid and be enforced to the full extent permitted by law. 
 29.6. Jurisdiction. This Lease shall be construed
and enforced in accordance with the laws of the State of California. Any action that in any way involves the rights, duties 

 
and obligations of the parties under this Lease may (and if against Landlord, shall) be brought in the courts of the State of California or the United States District Court for the District of
California, and the parties hereto hereby submit to the personal jurisdiction of said courts. 
 29.7. Attorneys’ Fees. In the
event that either Landlord or Tenant fails to perform any of its obligations under this Lease or in the event a dispute arises concerning the meaning or interpretation of any provision of this Lease, the defaulting party or the party not prevailing
in such dispute, as the case may be, shall pay any and all costs and expenses incurred by the other party in enforcing or establishing its rights hereunder, including, without limitation, court costs, costs of arbitration and reasonable
attorneys’ fees. 
 29.8. Waiver of Jury Trial. Landlord and Tenant each hereby voluntarily and knowingly waive and relinquish
their right to a trial by jury in any action, proceeding or counterclaim brought by either against the other on any matter whatsoever arising out of or in any way connected with this Lease, the relationship of Landlord with Tenant, or Tenant’s
use or occupancy of the Premises, including any claim of injury or damage, and any emergency and other statutory remedy with respect thereto. 

29.9. No Counterclaim by Tenant. In the event Landlord commence any proceedings for nonpayment of rent or other charges payable by
Tenant under this Lease, Tenant will not interpose any counterclaim of whatever nature or description in any such proceedings. This shall not, however, be construed as a waiver of the Tenant’s right to assert such claims in any separate action
or actions brought by the Tenant. 
 29.10. Light and Air. Tenant covenants and agrees that no diminution of light, air or view by
any structure that may hereafter be erected (whether or not by Landlord) shall entitle Tenant to any reduction of the Base Rent or Additional Rent under this Lease, result in any liability of Landlord to Tenant, or in any other way affect this Lease
or Tenant’s obligations hereunder. 
 29.11. Lease Memorandum. Neither Landlord nor Tenant shall record this Lease or a short
form memorandum hereof without the consent of the other. 
 29.12. Confidentiality. The parties agree that neither of them shall make
public the terms and conditions of this Lease or the fact that they have entered into this Lease to any person other than a party’s accountants, attorneys, lenders, brokers, prospective ground lessees, investors, consultants or financial
advisors without first obtaining the written permission from the other party, except to the extent otherwise required by Applicable Law. 

29.13. Terms. The term “Premises” includes the space leased hereby and any improvements now or hereafter installed therein or
attached thereto. The words “Landlord” and “Tenant” as used herein shall include the plural as well as the singular. If there is more than one Tenant or Landlord, the obligations under this Lease imposed on Tenant or Landlord
shall be joint and several. The captions preceding the articles of this Lease have been inserted solely as a matter of convenience and such captions in no way define or limit the scope or intent of any provision of this Lease. 

29.14. Review and Approval. The review, approval, inspection or examination by Landlord of any item to be reviewed, approved, inspected
or examined by Landlord under the terms of this Lease or the exhibits attached hereto shall not constitute the assumption of any responsibility by Landlord for either the accuracy or sufficiency of any such item or the quality of

 
suitability of such item for its intended use. Any such review, approval, inspection or examination by Landlord is for the sole purpose of protecting Landlord’s interests in the Property and
under this Lease, and no third parties, including, without limitation, Tenant or any person or entity claiming through or under Tenant, or the contractors, agents, servants, employees, visitors or licensees of Tenant or any such person or entity,
shall have any rights hereunder with respect to such review, approval, inspection or examination by Landlord. 
 29.15. No Beneficiaries.
This Lease shall not confer or be deemed to confer upon any person or entity other than the parties hereto, any right or interest, including without limitation, any third party status or any right to enforce any provision of this Lease. 

29.16. Time of the Essence. Time is of the essence in respect of all provisions of this Lease in which a definite time for performance
is specified. 
 29.17. Modification of Lease. In the event of any ruling or threat by the Internal Revenue Service, or opinion of
counsel, that all or part of the Rent paid or to be paid to Landlord under this Lease will be subject to the income tax or unrelated business taxable income, Tenant agrees to modify this Lease to avoid such tax; provided that such modifications will
not result in any increase in Rent, or any increased obligations of Tenant under this Lease. Landlord will pay all Tenants’ reasonable costs incurred in reviewing and negotiating any such lease modification, including reasonable attorneys’
and accountants’ fees. 
 29.18. Construction. This Lease has been negotiated extensively by Landlord and Tenant with and upon
the advice of their respective legal counsel, all of whom have participated in the drafting hereof. Consequently, Landlord and Tenant agree that no party shall be deemed to be the drafter of this Lease and in the event this Lease is ever construed
by a court of law, such court shall not construe this Lease or any provision of this Lease against any party as the drafter of the Lease. 

29.19. Survival. The obligations of this Lease shall survive the expiration of the Term to the extent necessary to implement any
requirement for the performance of obligations or forbearance of an act by either party hereto which has not been completed prior to the termination of this Lease. Such survival shall be to the extent reasonably necessary to fulfill the intent
thereof, or if specified, to the extent of such specification, as same is reasonably necessary to perform the obligations and/or forbearance of an act set forth in such term, covenant or condition. Notwithstanding the foregoing, in the event a
specific term, covenant or condition is expressly provided for in such a clear fashion as to indicate that such performance of an obligation or forbearance of an act is no longer required, then the specific shall govern over this general provisions
of this Lease. 
 29.20. Counterparts. This Lease may be executed in counterparts, each of which shall be an original, and all of
which together shall constitute one original of the Lease. 

 IN WITNESS WHEREOF, Landlord and Tenant have executed this Lease as of the Effective Date. 

 

					
	LANDLORD:
		
			Diamond Marina LLC
		
			a California limited liability company
			
			By:		 /s/ Stephen P. Diamond

			
			Name:		 Stephen P. Diamond

			
			Its:		 Manager

		
			Diamond Marina II LLC
		
			a California limited liability company
			
			By:		 /s/ Andrew Diamond

			
			Name:		 Andrew Diamond

			
			Its:		 Manager

	
	TENANT:
		
			Allergen Research Corporation,
		
			a Delaware Corporation
			
			By:		 /s/ Stephen G. Dilly

			
			Name:		 Stephen G. Dilly

			
			Its:		 Chief Executive Officer

 GLOSSARY 

As used in this Lease, the following terms shall have the following meanings, applicable, as appropriate, to both the singular and plural form
of the terms defined below: 
 “Abated Rent” is defined in Section 15.2(g). 

“ADA” is defined in Section 11.1. 

“Additional Rent” is defined in Section 5.2. “Alterations” is as defined in Section 9.2.

 “Applicable Laws” are defined in Section 11.1. 

“Assignment” is defined in Section 14.1. 

“Base Rent” means the amount stated in Article 1, to be adjusted and payable in accordance with Article 5. 

“Building” is defined in Section 2.1. 

“Building Structure” is defined in Section 8.1. 

“Building Systems” are defined in Section 7.2(b). 

“Business Days” means Monday through Friday, excluding Saturdays, Sundays and federal and state legal holidays. 

“Common Area” is defined in Section 2.2. 

“Commencement Date” means the date specified in Article 1. 

“Complete Transfer Notice” is defined in Section 14.2. 

“Effective Date” is defined in the introductory paragraph of this Lease. 

“Environmental Activity” is defined in Section 12.1(a). 

“Environmental Investigation” is defined in Section 12.7. 

“Environmental Laws” are defined in Section 12.1(b). 

“Event of Default” is defined in Section 15.1. 

“Excess Rent” is defined in Section 14.4. 

“Expiration Date” means the date specified in Article 1. 

 “Hazardous Material” is defined in Section 12.1(c). 

“Initial Base Rent” is defined in Article 1. 

“Interest Rate” is defined in Section 5.3. 

“Landlord” is defined in the introductory paragraph to this Lease. 

“Landlord’s Agents” is defined in Section 12.5. 

“Landlord’s Expense Statement” is defined in Section 7.4. 

“Offer” is defined in Section 14.5. 

“Operating Expenses” are defined in Section 7.2. 

“Permitted Transferee” is defined in Section 14.7. 

“Permitted Transfers” is defined in Section 14.7. 

“Premises” is defined in Section 2.1. 

“Prevailing Market Rent” is defined in Exhibit C. 

“Property” is defined in Section 2.2. 

“Real Estate Taxes” are defined in Section 7.2(a). 

“Renewal Option” is defined in Section 4.4. 

“Renewal Term” is defined in Section 4.4. 

“Rent” means Base Rent, Additional Rent, and all other sums due from Tenant under this Lease. 

“Rent Commencement Date” is defined in Article 1. 

“Rules and Regulations” is defined in Section 23.1. 

“Scheduled Date for Delivery of the Premises” is specified in Article 1. 

“Security Deposit” is defined in Article 1 and Section 5.4. 

“Sublease” is defined in Section 14.1. 

“Substituted Premises” is defined in Section 4.5. 

“Successor” is defined in Section 16.5. 

“Supplemental Investigation” is defined in Section 12.7. 

“Tenant” is defined in the introductory paragraph to this Lease. 

 “Tenant Improvement Work” is defined in Section 9.1. 

“Tenant Obligations” is defined in Section 8.2. 

“Tenant Relocation Allowance” is defined in Section 9.6. 

“Tenant Systems” is defined in Section 8.2. 

“Tenant’s Agents” is defined in Section 2.2. 

“Tenant’s Hazardous Materials” is defined in Section 12.1(d). 

“Tenant’s Property” is defined in Section 9.5. 

“Tenant’s Special Systems” is defined in Section 7.8. 

“Term” is defined in Article 1 and Section 4.1. 

“Termination Date” is defined in Section 4.1. 

“Termination Notice” is defined in Section 4.2. 

“Transfer Costs” is defined in Section 14.4. 

“Transfer Notice” is defined in Section 14.2. 

“Transferee” is defined in Section 14.2. 

“Work Letter” is defined in Section 9.1 and attached hereto as Exhibit E. 

 EXHIBIT A 

FLOOR PLAN OF THE PREMISES AS OF THE EFFECTIVE DATE 
  

 

 EXHIBIT B 

NOTICE OF COMMENCEMENT DATE, RENT COMMENCEMENT 

DATE, EXPIRATION DATE, BASE RENT AND RENTABLE AREA 

(Letterhead of Landlord) 
 (Date) 

 
  
  

 
  

			
	Attention:		  

 Re: Lease between Diamond Marina LLC and Diamond Marina II LLC (Landlord), and Allergan Research Corporation
(Tenant), for Premises located at 8000 Marina Boulevard, Brisbane, California 
 Gentlemen/Ladies: 

This letter will confirm the following for all purposes under the Lease: 

 

	
	The Commencement Date is
                                         
                                  
	The Rent Commencement Date is
                                         
                         
	The Expiration Date is
                                         
                                         
  
	The Rentable Area of the Premises is
                                         
                    
	The Initial Base Rent is
                                         
                                         
 

 Please acknowledge your acceptance of this letter by signing and returning two copies of this letter. 

Very truly yours, 
  

									
	DIAMOND MARINA LLC				DIAMOND MARINA II LLC
					
	By:		  
				By:		  

	Name:		  
				Name:		  

	Its:		  
				Its:		  

				
	Accepted and Agreed:						
				
	ALLERGEN RESEARCH CORPORATION						
					
	By:		  
						
	Its:		  
						
	Name:		  
						
	Dated:		  
						

 EXHIBIT C 

DETERMINATION OF PREVAILING MARKET RENT 

The term “Prevailing Market Rent” means the base monthly rent per rentable square foot, full service, for direct
leases from the landlord (as opposed to subleases) of space of comparable size to the Premises and in Class A office buildings located in North San Mateo County similar in quality to the Premises for a comparable term, taking into account any
additional rent and all other payments or escalations then being charged and allowances and economic concessions being given for such comparable space over a comparable term. The Prevailing Market Rent shall be determined by Landlord and Landlord
shall give Tenant written notice of such determination not later than thirty (30) days after delivery by Tenant of Tenant’s notice of exercise of the Renewal Option. If Tenant disputes Landlord’s determination of the Prevailing Market
Rent, Tenant shall so notify Landlord within fifteen (15) days following Landlord’s notice to Tenant of Landlord’s determination and, in such case, the Prevailing Market Rent shall be determined as follows: 

(a) Within thirty (30) days following Tenant’s notice to Landlord that it disputes Landlord’s determination of the Prevailing
Market Rent, Landlord and Tenant shall meet no less than two (2) times, at a mutually agreeable time and place, to attempt to agree upon the Prevailing Market Rent. 

(b) If within this 30-day period Landlord and Tenant cannot reach agreement as to the Prevailing Market Rent, they shall each select one
appraiser to determine the Prevailing Market Rent. Each such appraiser shall arrive at a determination of the Prevailing Market Rent and submit his or her conclusions to Landlord and Tenant within thirty (30) days after the expiration of the
30-day consultation period described in (a) above. 
 (c) If only one appraisal is submitted within the requisite time period, it shall
be deemed to be the Prevailing Market Rent. If both appraisals are submitted within such time period, and if the two appraisals so submitted differ by less than ten (10) percent of the higher of the two, the average of the two shall be the
Prevailing Market Rent. If the two appraisals differ by more than ten (10) percent of the higher of the two, then the two appraisers shall immediately select a third appraiser who will within thirty (30) days of his or her selection make a
determination of the Prevailing Market Rent and submit such determination to Landlord and Tenant. This third appraisal will then be averaged with the closer of the previous two appraisals and the result shall be the Prevailing Market Rent. 

(d) All appraisers specified pursuant hereto shall be members of the American Institute of Real Estate Appraisers with not less than five
(5) years experience appraising office, research and development and industrial properties in the San Francisco/Peninsula/Silicon Valley area. Each party shall pay the cost of the appraiser selected by such party and one-half of the cost of the
third appraiser plus one-half of any other costs incurred in the determination. 

 EXHIBIT D 

ACCEPTANCE FORM 
 This
Acceptance form is executed with reference to that certain Lease dated as of February 23, 2015 by and between DIAMOND MARINA LLC and DIAMOND MARINA 11 LLC, (“Landlord”), and ALLERGEN RESEARCH CORPORATION
(“Tenant”). Terms defined in the Lease and the exhibits thereto shall have the same meaning when used herein. 
 Tenant
hereby certifies to Landlord that Tenant has inspected the Premises as of                      (the “Date of Inspection”). Tenant
further acknowledges that Tenant hereby accepts the Premises in its existing condition, subject to the provisions of the Lease. 
 The
person executing this Acceptance Form on behalf of Tenant represents and warrants to Landlord that such person is duly authorized to execute this Acceptance Form and that this Acceptance Form has been duly authorized, executed and delivered on
behalf of Tenant. 
 THIS ACCEPTANCE FORM is executed by Tenant as of the Date of Inspection. 

 

					
			TENANT:
		
			ALLERGEN RESEARCH CORPORATION
			
			By:		  

			Name:		  

			
			Its:		  

 EXHIBIT E 

TENANT IMPROVEMENT WORK — WORK 

LETTER 
 Tenant Improvement
Work. Landlord at Landlord’s expense shall Deliver the Premises to Tenant having completed the following “Tenant Improvement Work” at its sole cost and expense: 

 

	 	1)	Consistent with the “Plan” attached hereto as Exhibit E-1, Landlord shall construct new interior improvements consisting of ten offices, a board room, a reception area, an IT closet. 

 

	 	2)	With the construction of new walls, Landlord shall also perform related as-needed modifications to the lighting fixture and switch layout, HVAC System distribution, and Fire Life Safety & Sprinkler
distribution. 

  

	 	3)	Electrical: there shall be at least 2 electric outlets per office, j-boxes for Tenant’s workstations, and miscellaneous electric outlets for Tenant’s printers, appliances, board room AV equipment, network
equipment, and other typical standard office needs. 

  

	 	4)	The new rooms shall be constructed with full-height doors, frames, and glass sidelights, consistent with the finishes for the pre-existing offices. 

 

	 	5)	All new building standard carpet tiles shall be installed throughout the office area. The reception area flooring shall be polished concrete. 

 

	 	6)	Walls shall primarily be painted white, with an accent wall color for selected walls. In the conference rooms, selected walls shall have Dry Erase Paint. 

 

	 	7)	The existing ceiling lighting, grid and tiles shall remain, with the cleaning, repair, or replacement of any damaged or stained ceiling tiles so that the ceiling grid looks in good condition. 

 

	 	8)	The existing exterior window blinds shall remain, with the cleaning, repair, or replacement of any damaged or stained window blinds so that the window blinds look in good condition. 

Tenant’s Construction Contact. Tenant’s Construction Contact, who shall be empowered by Tenant to make decisions and respond to
questions raised by Landlord during the construction of Tenant Improvement Work, shall be: Howard Raff, [***] 
 Special Conditions.
All of Landlord’s work shall be performed in a good and workmanlike manner, using materials of good quality and in accordance with law. Landlord shall bear responsibility to construct all improvements consistent with any applicable building
codes and laws. Tenant agrees that Landlord has the right to modify the Tenant Improvement Work as required by law. Tenant agrees to promptly respond to any inquiry or question of Landlord for the construction of these improvements. Following
Delivery of the Premises, Landlord shall have no further responsibility to perform improvements to the Premises, subject to a Punch List of minor items to be completed following Delivery and otherwise subject to the terms of the Lease. 

Exclusions. For avoidance of doubt, the following is excluded from the Landlord’s Tenant Improvement Work: furniture, fixtures, equipment,
network cabling, TV cabling and service, AV systems, office signage, specialty finishes, cabinetry, special power systems, security systems, break room appliances (excl. dishwasher and garbage disposal), moving & relocation, server room
set-up, or any other items not included above. 

 EXHIBIT E-1 

RECONFIGURED FLOOR PLANEX-10.4

 Exhibit 10.4 

[***] CERTAIN INFORMATION IN THIS DOCUMENT HAS BEEN OMITTED AND FILED SEPARATELY 

WITH THE SECURITIES AND EXCHANGE COMMISSION. CONFIDENTIAL TREATMENT HAS BEEN 

REQUESTED WITH RESPECT TO THE OMITTED PORTION 

LEASE 
 THIS LEASE, made
and entered into this 8th day of June, 2015, by and between MID A GROUP, LLC, a Florida limited liability company (hereinafter ‘the “Landlord”) and ALLERGEN RESEARCH CORPORATION, a California corporation (hereinafter the
‘Tenant”), 
 W I T N E S S E T H : 

1. Premises. The Landlord is the owner of certain real property located at 5733 Myerlake Circle, Clearwater, Florida, which is legally
described on Exhibit “A” attached hereto (the “Property”). There is a building on the Property containing approximately 40,000 square feet (the “Building”). The entire Property, including the Building and the parking,
retention and landscaping areas appurtenant thereto are reflected on a reduced copy of the survey attached hereto as Exhibit “B”, and shall, for convenience, hereinafter be referred to as the “Project”. On the Term Commencement
Date (as defined below), Landlord leases to Tenant and Tenant leases from Landlord the west 20,000 square foot portion of the Building as outlined in green on Exhibit “B” attached hereto, together with the rights of the Tenant and the
other tenant(s) in the Building and those doing business with them to use the Common Areas (as defined below) appurtenant to the Building (“the Premises”). 

2. Term. The initial term of this Lease (“Initial Term”) shall be for ten (10) years, commencing upon substantial
completion of Landlord’s Work as outlined in Exhibit “E” attached hereto (the “Term Commencement Date”) and ending one hundred and twenty months (120) months thereafter. The parties shall execute and deliver the
Commencement Date Certificate in the form set forth in Exhibit “C” attached hereto in order to confirm and memorialize the Commencement Date. The first “Lease Year” of this Lease shall be deemed to commence on the Term
Commencement Date and shall end on the first annual anniversary of such date. Each subsequent Lease Year of this Lease shall commence on the annual anniversary of the Term Commencement Date thereafter. 

 3. Base Rent. 

(a) Tenant shall pay to Landlord as rent during the term of this Lease (“Base Rent”) the amount set forth on Exhibit “D”
attached hereto. 
 (b) All monthly installments of Base Rent will be due on the 1st
day of the month until the term of this Lease expires and shall be paid at the Landlord’s address set forth herein (or at such address as Landlord from time to time directs in a written notice) beginning on the Term Commencement Date, without
set off, counterclaim or demand. Wherever it is provided in this Lease that the Tenant is required, except as otherwise provided herein, to make any additional payment to Landlord, such payment will be deemed to be additional rent for the Premises
(“Additional Rent”) and all remedies for the non-payment of Base Rent will be applicable thereto. 
 (c) If Tenant fails to pay,
within ten (10) days after the same is due and payable, any Base Rent or any Additional Rent, or any other amounts or charges payable by Tenant under this Lease, such unpaid amounts will be increased by a late charge equal to five percent
(5%) of the unpaid amount. 
 (d) Tenant will pay to Landlord all sales, excise, use and/or rental tax imposed by the State of
Florida, the county or municipal government, or any other governmental agency with respect to the Base Rent, Additional Rent and all other charges and payments payable by Tenant to or for the account of Landlord pursuant to the terms of this Lease.

 (e) Simultaneous with the execution of this Lease, Tenant shall pay Landlord the sum of Thirty-Four Thousand Five Hundred Fifty-Two and
09/100 ($34,552.09) Dollars representing the following: 
  

					
	 First month’s rent
		$	12,500.00	  
	 First month’s property operating costs
		 	3,916.67	  
	 Last month’s rent
		 	15,875.00	  
		  	  
	  
	 
	 Subtotal
		 	32,291.67	  
	 Sales tax (7%)
		 	2,260.42	  
		  	  
	  
	 
	 Total
		$	34,552.09	  

 4. Landlord’s and Tenant’s Work. Upon issuance of a permit for Landlord’s
Work, Landlord shall commence the work as set forth in Exhibit “E” attached hereto, and shall have ninety (90) days to complete the work. 

After Landlord’s ninety (90) day period, Tenant and Tenant’s contractor (“Contractor”) may commence their work as per
plans and specifications approved by Landlord. Tenant’s Work must be permitted by a licensed, bonded, and insured contractor approved by Landlord. Contractor must issue a hold harmless agreement for the benefit of the Landlord. During
Landlord’s ninety (90) day period, Contractor shall be permitted access to the Premises upon twenty-four hours prior notice and accompanied by Landlord’s representative, for the purpose of planning for Tenant’s Work, but not for
commencing any of Tenant’s Work. 
 5. Utilities. Effective at the Term Commencement Date, Tenant will, at its own expense, pay
and discharge all costs and charges for water, electricity, gas, telephone and garbage collection (including dumpster) to be furnished in connection with or for the use of the Premises, or any part thereof, including the making of deposits with the
proper authorities or persons in order to secure such services. At the time of the Term Commencement Date, if any of the aforesaid services are being furnished to the Premises from accounts that are in the name of the Landlord, Tenant agrees to
immediately change such sendee accounts with the proper authorities or persons into the name of the Tenant and the Landlord agrees to cooperate in all reasonable respects with the Tenant to accomplish same. In the event the Tenant fails to change
such accounts into Tenant’s name within ten (10) days alter the Term Commencement Date, Landlord shall have the right, after providing ten (10) days written notice to Tenant, to notify the proper authorities or persons to terminate
the furnishing of such services to the Premises without incurring any liability to Tenant on account of such termination. 

 6. Taxes. During the term of this Lease, Tenant agrees to pay all real estate and personal
property taxes assessed against the Premises. Real estate taxes for any portion of a calendar year shall be prorated according to Tenant’s occupancy during such year. “Real estate taxes” shall include ad valorem taxes, general and
special assessments and, with Tenant’s written consent, any fees, expenses or costs (including reasonable attorney’s fees, expert fees and the like) incurred by Landlord in protesting or contesting any assessment levied, tax valuation or
tax rate. The obligations hereunder are to be paid in accordance with paragraph 35 herein. If the real estate taxes assessed against the Premises are included within a total assessment of the Project as reflected on Exhibit “B” and legally
described on page 1 hereof, the portion of such total real estate taxes which are attributable to the Premises shall be the percentage figure determined by dividing the square footage of the Premises in the Building by the total square footage of
the Building of which the Premises are a part. It is acknowledged that such percentage is in the amount of fifty percent (50%). 
 7.
Tenant Improvements. Tenant will not make any improvements, installations, alterations or additions in or to the improvements to the Premises without the written consent of Landlord, which consent shall not be unreasonably withheld,
conditioned or delayed. Any such improvements shall be installed at Tenant’s expense in accordance with plans approved by Landlord and only by such contractor as Landlord may approve, provided, however, that consent to such plans and the
contractor selected by Tenant shall not be unreasonably withheld, conditioned or delayed. If Landlord consents to such improvements, alterations, or additions, Tenant agrees to permit Landlord access to the Premises while such work is being
performed in order for Landlord to verify that such improvements, alterations or additions are being done in accordance with the plans approved by Landlord. 

 8. Liens and Charges. The Tenant shall have no authority to incur, create or permit, and
shall not incur, create or permit, any lien for labor or materials or services to attach to the interest or estate of either the Landlord or the Tenant in the Premises; and neither the Tenant, nor anyone claiming by, through or under the Tenant,
shall have any right to file or place any labor or material lien of any kind or character whatsoever or any mechanics lien or other lien of any kind, upon the Premises so as to encumber or affect the title of the Landlord, and all persons
contracting with the Tenant directly or indirectly, or with any person who in turn is contracting with the Tenant, for the erection, construction, installation, alteration or repair of the Premises or any improvements therein or thereon, including
fixtures and equipment, and all material-men, contractors, mechanics, laborers, architects, engineers, and others are hereby charged with notice that as and from the date of this instrument, they and each of them must look to the Tenant only to
secure the payment of any bills or charges or claims for work done, or materials furnished, or services rendered or performed during the term hereby demised. 

9. Use. Tenant shall have the right to use the Premises for office, warehouse and light manufacturing and any purposes reasonably
related thereto. Landlord represents that Tenant’s intended use will not violate any local zoning or land use regulations. Tenant will not use the Premises for any illegal trade or business, including uses or purposes in violation of local
zoning or land use regulations. 
 10. Assignment, Subletting. Tenant shall have the right to assign or sublet all or a portion of
the Premises, but only with the Landlord’s prior written consent. Such consent by Landlord shall not be unreasonably withheld, conditioned or delayed. Any attempted transfer, assignment or subletting without Landlord’s written consent
shall be void and confer no rights upon any third person. No assignment or subletting will relieve Tenant of any obligations under this Lease. The 

 
consent by Landlord to any transfer, assignment or subletting will not be deemed to be a waiver on the part of the Landlord of any prohibition against any future transfer, assignment or
subletting. If Landlord consents to any transfer, assignment or subletting, such consent will not be effective unless and until Tenant gives notice of the assignment and a copy of the assignment agreement or sublease to Landlord, and the transferee,
assignee or sublessee delivers to Landlord a written agreement in form and substance satisfactory to the Landlord, pursuant to which such transferee, assignee or sublessee assumes all of the obligations and liabilities of the Tenant under the Lease.
Tenant may assign the Lease to a wholly owned subsidiary without the Landlord’s permission. 
 11. Landlord’s Rights of Access
and Inspection. Tenant will permit the Landlord to enter upon said Premises upon twenty four (24) hours’ notice during the usual business hours under Tenant supervision and complying with Tenant’s requirements for proper gowning
and other “clean-room” procedures for the purpose of making inspections or repairs, for the purposes of obeying any laws or orders of any duly constituted governmental or municipal authorities, and/or for the purpose of exhibiting the
Premises to prospective tenants or purchasers within four (4) months of the expiration of the Lease, provided Landlord does not unreasonably or unnecessarily interfere with the operation of Tenant’s business. In making such inspections or
repairs, Landlord shall observe all security regulations of Tenant and Landlord and its agents shall hold in confidence any information concerning business or products of Tenant which they, or any of them, may discover while present on said
Premises. 
 12. Damage or Destruction. The parties hereto agree, if by virtue of fire, storm or cause other than a negligent or
deliberate act of the Tenant, the Premises become partly or wholly untenantable, then and in that event, the rent shall abate in proportion to the amount of untenantability of said Premises tor so long as they are untenantable. In the event the
Premises are not totally destroyed, the Landlord agrees to rebuild the Premises with all possible dispatch 

 
and deliver the same to the Tenant within a period of thirty (30) days after the event causing the destruction. In the event the Premises are greater than seventy-five (75%) percent
destroyed, then Tenant or Landlord shall have the option to terminate this Lease within a period of ten (10) days after the said destruction. In the event this Lease is not thus terminated, the Landlord agrees to rebuild the Premises with all
possible dispatch and deliver the same to the Tenant within a period of not more than thirty (30) days after an event causing total destruction. However, in no event shall Landlord be obligated to do any rebuilding if the remaining term of this
Lease shall have less than one (1) year to run following the expected completion of such rebuilding and Landlord notifies Tenant of its intention not to rebuild within a period of ten (10) days after said destruction. Such an election by
Landlord not to rebuild shall constitute a termination of this Lease effective as of the date of the event causing the damage or destruction. 

13. Condemnation. If any substantial portion of the Premises shall be taken by eminent domain, Tenant shall have the right to terminate
this Lease as of the date of taking by giving written notice of such termination to the Landlord within fifteen (15) days following the date of such taking, and in the event of such termination, rent shall cease as of the date of such
termination (or if earlier, the date the condemning authority takes possession of the Premises) and any rent paid beyond that date shall be refunded to the Tenant. Whether or not the Tenant shall exercise such right, the Landlord and Tenant shall
have and retain their respective rights to compensation from the condemning authority in connection with and following a taking by eminent domain. If Tenant does not terminate this Lease following a substantial taking by eminent domain or if the
portion of the Premises taken is not substantial, the rent payable under this Lease for the remainder of the term shall be reduced as of the date of taking in the proportion that the area of the part taken bears to the total area of the Premises
just prior to such taking (or, if earlier, the date the condemning authority takes possession of the Premises affected by the condemnation) and Landlord shall make any necessary repairs to the remaining Improvements affected by the condemnation.
Substantial, as used herein, shall refer to the ability of Tenant to carry on its normal business. 

 14. Insurance. Tenant shall, as of the date of execution of this Lease, and during the
full term of this Lease, including renewals, and its own expense, carry Broad Form Comprehensive General Liability Insurance, including, but not limited to, coverage for personal injuries with limits of not less than $2,000,000.00 combined single
limit for death, personal injury and property damage, per occurrence, and Contractual Liability. 
 Landlord shall pay for and maintain,
subject to reimbursement by Tenant as hereinafter provided, during the full term of this Lease, including any renewal, the following policies of insurance covering the Project; 

(a) All Risk Property Insurance. Upon all Improvements and alterations, including, but not limited to, fire and extended coverage, vandalism,
malicious mischief and sprinkler leakage in the amount of one hundred percent (100%) of full replacement costs. 
 (b) Flood
Insurance. Landlord will purchase flood insurance coverage for the Project, if Landlord advises Tenant that the Project is in an insurance flood zone, in an amount per the appraised value of the building. 

It is acknowledged that the foregoing insurance to be maintained by Landlord shall be part of a master policy covering the Building and the
Common Areas reflected on Exhibit “B” attached hereto. Tenant shall reimburse Landlord for fifty percent (50%) of the premiums paid by Landlord in connection with the above-referenced insurance. Such costs shall be prorated for any
portion of the term which commences after the effective date of such policy(ies) or for the period of such policy(ies) which extends beyond the term so as to account for Tenant’s proportionate share thereof. Each of the parties shall furnish
certificates that the insurance required to be carried by each party pursuant to the terms of this paragraph is in force and reflecting each of the parties as the named insured under said insurance policies and the Landlord’s mortgagee as an

 
additional insured. All of the aforesaid insurance certificates shall further provide that the insurance policies may not be canceled until after thirty (30) days written notice to Landlord
and Tenant and Landlord’s Mortgagee, if any. The obligations hereunder are to be paid in accordance with paragraph 35 herein. 
 15.
Common Area. The term “common area” is defined for all purposes of this Lease as that part of the Project intended for the common use of all tenants, including among other facilities, roof, parking lot, landscaping, fire sprinkler
system, fire alarm monitoring, association fees, and the like. Landlord reserves the right to change from time to time the dimensions and locations of the Common Area. Tenant, and its employees and customers, and when duly authorized pursuant to the
provisions of this Lease, its subtenants, licensees and concessionaires, shall have the non-exclusive right to use the Common Area as constituted from time to time, such use to be in common with Landlord, other tenants in the Building, subject to
the rights of governmental authorities, easements, other restrictions of record, and such reasonable rules and regulations governing use as Landlord may from time to time prescribe. For example, and without limiting the generality of Landlord’s
ability to establish rules and regulations governing all aspects of the Common Area, Tenant agrees as follows: 
 (a) Tenant shall have
fifty (50) dedicated parking spaces within the Project to be used by Tenant’s employees or guests. Landlord may from time to time designate specific areas within the Project in which automobiles owned by tenants in the Building, their
employees, subtenants, licensees and concessionaires shall be parked. 
 (b) Landlord may temporarily close any part of the Common Area for
such periods of time as may be necessary to make repairs or alterations. 
 Landlord shall be responsible for the operation, management and
maintenance of the Common Area, the manner of maintenance and the expenditures therefore to be in the sole discretion of the Landlord. Landlord shall be the sole determinant of the type and amount of

 
security services to be provided, if any. Landlord shall not be liable to Tenant and Tenant hereby waives any claim against Landlord provided Landlord’s negligence or willful misconduct is
not a significant contributing factor for (i) any unauthorized or criminal entry of third parties onto the Project, (ii) any damage to persons or property, or (iii) any loss of property in and about the Premises from any unauthorized
or criminal acts of third parties. 
 16. Maintenance and Repairs. Landlord shall maintain roof, foundation and structural load
bearing walls of the Building except for plate glass, windows, doors and other exterior openings, window and door frames, molding, closure devices, locks and hardware. Any penetrations or structural alterations to the roof by Tenant that may cause
damage to the roof shall be repaired at Tenant’s expense. Landlord shall also maintain the Common Area as defined in paragraph 15 above provided, however, Tenant shall reimburse, on a monthly basis, Landlord for fifty percent (50%) of
Landlord’s costs of maintaining the Common Area together with remitting Landlord a reasonable management fee. Subject to the foregoing, Tenant agrees to maintain the entire Premises at Tenant’s expense including, but not limited to, pest
control, the maintenance, repair and replacement of all lighting, heating, air conditioning, plumbing and other electrical, mechanical and electromotive installations, equipment and fixtures. Tenant shall, at its own expense, enter into a regularly
scheduled preventive maintenance/service contract with a maintenance contractor for servicing the heating and air conditioning systems and equipment within the Premises. Tenant shall, at the termination of the Lease, by lapse of time or otherwise,
surrender up said Premises in good order and condition, reasonable use and ordinary wear and tear excepted. 
 17. Absolute Net
Lease. It is the purpose and intent of the Landlord and the Tenant that except as otherwise specifically provided in this Lease, the rent shall be absolutely net to Landlord, so that the Lease shall yield, net, to Landlord, the rent specified in
paragraph 3 hereof and each month during the term of the Lease, and that, except as aforesaid, all costs, expenses and 

 
obligations set forth herein relating to Tenant’s occupancy of the Premises which may arise or become due during or with respect to the term of this Lease, shall be paid by the Tenant, in
accordance with the terms hereof. The provisions of this paragraph shall in no way be construed to require Tenant to make any mortgage payments which Landlord may owe in connection with the Premises. 

18. Signs. Tenant shall not be permitted to install, construct, inscribe, paint, affix or display any sign, advertisement, or logo
visible from the exterior of the Premises without Landlord’s prior written consent, which consent shall not be unreasonably withheld, conditioned or delayed. 

The exact size, design, configuration and placement of all signs, advertisements and logos shall be subject to the reasonable approval of
Landlord and any applicable governmental authorities. Under no circumstances may any sign, advertisement or logo violate any ordinance, rule or regulation of any governmental authority. Tenant hereby agrees to seek and obtain any and all
governmental approvals, permits or licenses necessary for the lawful operation and placement of any signs, advertisements, or logos approved by Landlord. 

All costs of installation, construction, erection, illumination (where appropriate), maintenance, repair and removal of any of the
above-referenced items shall be the obligation of Tenant. Before erecting or placing any signs, advertisements, or logos or beginning any construction pursuant to preparation for logos or beginning any construction pursuant to preparation for the
erection or placement thereof, Tenant shall submit to Landlord, for Landlord’s reasonable review and approval, detailed plans and specifications for all work to be performed. After obtaining Landlord’s approval of said plans and
specifications, the signs, advertisements, or logos are to be constructed pursuant to the plans and specifications without any deviation therefrom whatsoever. 

 Upon vacating the Premises, Tenant shall remove all signs, advertisements or logos and repair all
damage caused by such removal. Tenant’s obligation to observe or perform this covenant shall survive the expiration or termination of this Lease. 

Tenant hereby agrees to indemnify and hold Landlord harmless from and against any and all loss, cost, damage, claims, suits, actions for any
damage or injury to any person or property caused by the installation, construction, erection, maintenance, repair or removal of any of said signs, advertisements, or logos. 

19. Subordination. Tenant agrees to execute and deliver an instrument in standard form subordinating this Lease to the lien of any
Mortgage within thirty (30) days after receiving a written request from Landlord. Provided, however, in the instrument the Mortgagee must agree that, so long as Tenant is not in default under the provisions of this Lease: (a) this Lease
shall remain in full force and effect, (b) the possession of the Premises by Tenant shall not be disturbed, and (c) in the event of a foreclosure or other suit instituted pursuant to the mortgage, the suit shall not affect the rights of
Tenant under this Lease, but any purchaser of the Project as a result of such suit shall take the Project subject to this Lease and shall be bound by all of its terms. In the event of a foreclosure of any mortgage encumbering the Project, Tenant
agrees to attorn to the mortgagee or its successors in interest and recognize such party as Landlord under this Lease, provided Tenant receives in return a nondisturbance agreement from the foreclosing mortgagee or its successor in interest as set
forth immediately above. 
 20. Estoppel Certificates by Tenant. Tenant shall, within thirty (30) days after receiving a written
request from Landlord, make a statement in writing in standard form certifying: 
 (a) That the term of this Lease has commenced, setting
forth the date of such commencement; 
 (b) That this Lease is unmodified and in full force and effect (or, if there have been
modifications, that the Lease is in full force and effect as modified, stating the modification); 

 (c) Whether or not there are then existing any known offsets or defenses against the enforcement
of any of Tenant’s covenants hereunder (and if so, specifying them); 
 (d) The dates to which rent and other amounts have been paid
in advance, if any, and 
 (e) Whether or not Tenant has executed a leasehold mortgage or otherwise made any transfer or assignment of any
part of the leasehold estate. 
 Such statements shall be given with reasonable frequency and may be relied upon by any prospective
purchaser of the fee simple interest in the Premises or by any Mortgagee or its assignee. 
 21. Tenant’s Property. Tenant
agrees that all property belonging to or in the name of, custody or control of the Tenant or any occupant of the Premises which is in or on the Premises shall be there at the risk of the Tenant or such occupant only, and Landlord shall not be liable
to Tenant for any injury thereto or loss or destruction thereof except to the extent caused by Landlord, its agents or employees, or as otherwise provided in this Lease. Except to the extent caused by the negligence of the Landlord, or its agents or
employees, or as otherwise provided in this Lease, Tenant further agrees that Landlord shall not be liable to the Tenant for any injury, loss or damage to property on the Premises or on the common areas appurtenant thereto. Provided, however, that
this paragraph shall not excuse any liability of Landlord in the event the damage or injury is caused by a breach of any of Landlord’s warranties as to the Premises. 

22. Attorney’s Fees. If either party becomes a party to any litigation concerning this Lease, or the Project, solely by reason of
any act or omission of the other party or its authorized representatives, and through no fault of its own, the party that causes the other party to become involved in the litigation shall be liable to that party for reasonable attorney’s fees
and court costs incurred by it in the litigation. 

 If either party commences an action against the other party arising out of or in connection with
this Lease, the prevailing party shall be entitled to have and recover from the losing party reasonable attorney’s fees and costs of suit. 

23. Default. Default provisions: 

A. Unless excused pursuant to Section 24 of this Lease, the happening of any one or more of the following events shall, at the option of
Landlord, constitute a breach of this Lease on the part of Tenant and Landlord shall have such remedies as are herein provided. 
 (1) If
Tenant defaults in the payment of any rents payable to Landlord hereunder and such default shall continue for five (5) days after receipt by Tenant of written notice of such default; or 

(2) If Tenant petitions or applies to any tribunal for the appointment of a trustee or receiver of Tenant or any substantial part of the
assets of Tenant or commences any proceedings with respect to Tenant under any bankruptcy, reorganization, arrangements, insolvency, readjustment, dissolution or liquidation law of any jurisdiction; or 

(3) If any such petition or application of the type described in subparagraph (2) above is filed or any proceedings are commenced
against Tenant and Tenant, by any act, indicates its approval thereof, consents thereto or acquiesces therein, or an order is entered appointing such trustee or receiver, or adjudicating Tenant bankrupt or insolvent, or approving the petition in any
such proceedings, and such order remains in effect for more than ninety (90) days; or 
 (4) If Tenant fails to fully and promptly
perform any material act, term or provision required of it in the performance of this Lease. If a default is claimed under this subparagraph, written notice specifically specifying the nature of such claimed default shall be mailed to Tenant and
Tenant shall have thirty (30) days after receipt of such notice to cure said default or such longer time as may reasonably be necessary due to the nature of said default, so long as Tenant commences to cure such failure within such thirty
(30) day period and pursues such cure with due diligence. 

 B. Upon the happening of any of the above events of default, Landlord may, at Landlord’s
option: 
 (1) Terminate and end this Lease and reenter upon the Premises and at Landlord’s option, all of Tenant’s right, title
and interest under this Lease shall end and Tenant shall become a tenant at sufferance; or 
 (2) Except to the extent Landlord is able to
mitigate its damages after taking all reasonable actions to do so, elect to declare the entire rent for the balance of the term due and payable forthwith, and may proceed to collect its actual remaining damages by distress or otherwise; or 

(3) Take possession of the Premises and rent the same for the account of Tenant. 

The exercise of any of the above options shall not be deemed to be the exclusive remedy of Landlord. In addition thereto, Landlord shall have
the right of any of the provisions of the laws of the State of Florida governing default by Tenant, and, in any event of default by Tenant. 

24. Force Majeure. Landlord and Tenant shall be excused for the period of any delay in the performance of any of the obligations
hereunder when prevented from so doing by cause or causes beyond Landlord’s or Tenant’s reasonable control (other than financial causes) which shall include, without limitation, all labor disputes, civil commotion, war, war-like
operations, terrorism, invasion, rebellion, hostilities, military or usurped power, sabotage, governmental regulations or controls, fire or other casualty, inability to obtain any material or services (after diligent efforts), or through acts of
God. 
 25. Notice. The rent payable under the terms of this Lease and any notices to the Landlord shall be mailed to: 

MIDA GROUP, LLC 
 3071 118th Avenue North 
 St Petersburg, FL 33716 

or such other addresses as the Landlord may designate in writing. 

 Any notices to the Tenant shall be mailed to Tenant at the Premises or such other address as the Tenant may
designate in writing. 
 26. Waiver. No assent, expressed or implied, by either party to any breach of any of the other’s
covenants or agreements shall be deemed a waiver of any succeeding breach of the same covenant or agreement. No delay or omission on the part of Landlord or Tenant in exercising any right or remedy shall operate as a waiver thereof or the exercise
of any other right or remedy. 
 27. Surrender or Abandonment. If Tenant shall abandon or surrender the Premises, or be dispossessed
by process of law or otherwise, any personal property belonging to Tenant and left on the Premises for a period of fifteen (15) days after such abandonment or surrender shall be deemed to be abandoned, at the option of the Landlord. Provided,
however, the provisions regarding abandonment shall not be effective if Tenant is not in default under the terms of this Lease. 
 28.
Partial Invalidity. If any provision of this Lease is deemed invalid or unenforceable by a court of competent jurisdiction, such provision shall be ineffective to the extent of such invalidity or unenforceability only, without invalidating
the remainder of such provision or of the remaining provisions of this Lease. 
 29. Binding Effect. This Lease contains all of the
agreements, covenants and conditions between the parties hereto with respect to the subject matter hereof and may not be altered or modified orally or in any other manner, except by an agreement in writing signed by all of the parties hereto, or by
their respective successors in interest. The covenants and agreements herein contained shall be binding upon and shall inure to the benefit of the parties hereto and their respective heirs, personal representatives, successors and assigns. This
Lease constitutes a Florida contract and shall be construed according to the laws of that state. The parties agree that the venue for any litigation arising hereunder shall be in a Pinellas County court of competent jurisdiction. 

 30. Radon Disclosure. Radon is a naturally occurring radioactive gas that, when it has
accumulated in a building in sufficient quantities, may present health risks to persons who are exposed to it over time. Levels of radon that exceed federal and state guidelines have been found in buildings in Florida. Additional information
regarding radon and radon testing may be obtained from your county public health unit. Landlord has no knowledge that the radon levels on the Premises have or do currently exceed federal or state guidelines. 

31. (a) Hazardous Waste. Tenant shall not use, generate, manufacture, store or dispose of on, under or about the Project or
transport to or from the Project any flammable explosives, radioactive materials, hazardous wastes, toxic substances defined as or included in the definition of “hazardous substances”, “hazardous wastes”, “hazardous
materials”, or “toxic substances” under any applicable federal or state laws or regulations, unless any such substances are used by Tenant in the ordinary course of its business in accordance with applicable federal and state laws and
regulations. 
 (b) Tenant shall indemnify the Landlord and hold the Landlord harmless from any cost, liability or expense imposed upon the
Landlord under any local, state or federal law, ordinance, statute, rule, regulation, or judicial or administrative order because of or arising out of any environmental contamination of the Project or any contamination of groundwater or surrounding
lands because of or arising out of contamination of the Project due to the actions of Tenant or its agents, contractors or employees, 
 (c)
Landlord shall indemnify Tenant and hold the Tenant harmless from any cost, liability or expense imposed upon the Tenant undo: any local, state or federal law, ordinance, statute, rule, regulation or judicial or administrative order because of or
arising out of any environmental contamination of the Project or any contamination of groundwater or surrounding lands because of or arising out of contamination of the Project to the extent that it v/as not caused by the actions of Tenant or its
agents, contractors or employees. 

 32. Cautions. The captions, section numbers and article numbers appearing in this Lease
are inserted only as a matter of convenience and in no way define, limit, construe or describe the scope or intent of such sections or articles of this Lease, nor in any way affect this Lease. 

33. Quiet Enjoyment. Landlord covenants, promises and agrees with the Tenant, that the Tenant, on paying the said rent above hereby
reserved, and observing, performing and keeping all and singular the covenants and agreements herein contained, shall and may lawfully, peacefully and quietly have, hold, use, occupy and enjoy the Premises. 

34. Intentionally Omitted. 

35. Monthly Payment of Taxes, Insurance and Other Expenses. The expenses for real estate taxes, insurance, Common Area maintenance,
management fee and Building common expenses pursuant to the provisions of paragraphs 6, 14 and 16 respectively of this Lease are hereby, for convenience, referred to as Property Operating Costs. As Additional Rental hereunder, Tenant shall pay to
Landlord, monthly, in advance, the Property Operating Costs. Prior to the commencement of each year of the lease term, or as soon thereafter as is practical, Landlord shall give Tenant written notice of its estimate of the amounts payable under this
paragraph 35 for the ensuing year of the lease term, which estimate shall be based upon Property Operating Costs for the prior lease year. Provided, however, the amounts payable during the first year of the lease term shall be based on the
Landlord’s good faith estimate. Landlord’s estimate of Property Operating Costs during the first year of the lease term is in the amount of $47,000.00. If at any time or times it appears to Landlord that the amounts payable under this
paragraph 35 for the ensuing year will vary from its estimate by more than five percent (5%), Landlord may, by written notice to Tenant, revise its estimate for such year, and subsequent payments by Tenant, shall be based upon such revised estimate.
On the date each monthly rental payment is due as 

 
provided in paragraph 3 of this Lease, Tenant shall also pay to Landlord one- twelfth (1/12) of such estimated amounts, provided, if such notice is not given on or before the commencement
date of each year of the said lease term, Tenant shall continue to pay on the basis of the prior year’s estimate until the month after such notice is given. Within ninety (90) days after the close of each calendar year of the lease term,
or as soon after such ninety (90) day period as is practical, Landlord shall deliver to Tenant a statement of the amount payable under this paragraph 35 for such year certified by Landlord. If such statement shows an amount owing by Tenant that
is less than the estimated payments for such year previously made by Tenant, it should be accompanied by a refund of the excess by Landlord to Tenant. If such statement shows an amount owing by Tenant that is more than the estimated payments for
such year previously made by Tenant, Tenant shall pay the deficiency to Landlord within thirty (30) days after delivery of the statement. If Tenant shall dispute any such statement, it shall have the right during business hours and at
Landlord’s place of business to examine Landlord’s books and records with respect to such statement and dispute on not Less than three (3) days prior written notice to Landlord. Said examination shall take place within a sixty
(60) day period after Landlord has submitted such statement to Tenant. If Tenant has not disputed such statement, Tenant shall, as aforesaid, pay any amount due Landlord within thirty (30) days after delivery of the statement. 

36. [*** ]. Landlord does hereby [***] and upon the terms and conditions as set forth in this paragraph as follows: 

(a) [***] 
 (b)
[***] 
 (c) [***] 

(d) [***] 
 (e)
[***] 
 (f) [***] 

  
 [***] CERTAIN INFORMATION
IN THIS DOCUMENT HAS BEEN OMITTED AND FILED SEPARATELY 
 WITH THE SECURITIES AND EXCHANGE COMMISSION. CONFIDENTIAL TREATMENT HAS BEEN 

REQUESTED WITH RESPECT TO THE OMITTED PORTION 

 (g) [***] 

(h) [***] 
 (i)
[***] 
 37. Contingency. The parties hereto acknowledge that Landlord does not presently own the Project. This Lease is
contingent upon Landlord acquiring title to the Project on or before July 1, 2015. In the event Landlord fails to acquire the Project by such a date, this Lease shall become null and void and neither party shall have any liability to the other
pursuant to the terms of this Lease. 
 [SIGNATURE PAGE TO FOLLOW] 

  
 [***] CERTAIN INFORMATION
IN THIS DOCUMENT HAS BEEN OMITTED AND FILED SEPARATELY 
 WITH THE SECURITIES AND EXCHANGE COMMISSION. CONFIDENTIAL TREATMENT HAS BEEN 

REQUESTED WITH RESPECT TO THE OMITTED PORTION 

 IN WITNESS WHEREOF, the parties have caused these presents to be executed as of the day and year
first above written. 
  

							
	 Signed, Sealed and Delivered
 in the Presence
of:
				     MIDA GROUP, LLC, a Florida limited

    liability company

				
	  
				    By:		 /s/ Judy K. Humbarger

Judy K. Humbarger, Manager

“Landlord”

			
	  
 (As to Landlord)
				
					     ALLERGEN RESEARCH

    CORPORATION, a California corporation

			
	 /s/ Howard V. Raff
				

							
				
					      By:  		 /s/ S.C. Dilly

									
	 Howard V. Raff

(As to Tenant)
						Printed Name: 		S.C. Dilly
							Title:		CEO
									“Tenant”

 EXHIBIT “A” 

Legal Description 
 A portion of
Lot 13, RUBIN ICOT CENTER, as recorded in Plat Book 88, Pages 79 through 85, of the Public Records of Pinellas County, Florida, lying in Section 4, Township 30 South, Range 16 East, Pinellas County, Florida, and being more particularly
described as follows: 
 Commence at the Southeast corner of Lot 1.3 of said RUBIN ICOT CENTER for a Point of Beginning; thence
N.89°41’16”W., and along the South line of said Lot 13, 404.64 feet; thence N.00°26’29”E., 385.17 feet to a Point on the South right-of-way line of Myerlake Circle; thence S.89°33’31”E. and along said
rlght-of-way line, 202.00 feet to a curve concave to the Southwest and having a radius of 200.00 feet; thence along said curve 311.32 feet through a central angle of 89°11’13” (chord bearing S.44°57’55”E., 280.83 feet);
thence S.00°22’18”E., 187.11 feet to the Point of Beginning. 

 

 

 EXHIBIT “C” 

COMMENCEMENT DATE CERTIFICATE 

This Commencement Date Certificate is made as of this      day of
            , 2015, between MID A GROUP, LLC (“Landlord”), and ALLERGEN RESEARCH CORPORATION, (“Tenant”). 

WHEREAS, the parties entered into a lease dated
                    . (“Lease”), attached hereto and incorporated by reference, in which Landlord leased to Tenant 20,000 square
feet (“Premises”) in that certain Project situated at 5733 Myerlake Circle, Largo, Florida, 
 WHEREAS, Landlord and Tenant desire
to confirm the Commencement Date and certain other facts concerning the Lease. 
 NOW, THEREFORE, in consideration of the mutual covenants
herein contained and further good and valuable consideration, then parties hereto incorporate the following into the terms of their existing Lease: 
  

	 	1.	The actual rentable square footage of the Project is 40,000 square feet. The Premises contains 20,000 square feet The Tenant’s Pro-Rata share is fifty percent (50%). 

 

	 	2.	Landlord’s Work was complete according to the terms of the Lease on                     . and the Tenant
assumed possession of the Premises on such date. Other key dates are as follows: 

  

	 	a)	The Commencement Date of the Lease is
                                         
  . 

  

	 	b)	The Expiration Date of the Lease is
                                         
            . 

  

	 	3.	Except for the specific modifications to the Lease contained in this Commencement Date Certificate, all terms of the Lease shall remain unchanged, and are hereby ratified, republished and reaffirmed and are incorporated
into this Agreement 

 [SIGNATURE PAGE TO FOLLOW] 

 IN WITNESS WHEREOF, the parties have caused these presents to be executed as of the day and year
first above written. 
  

							
	 Signed, Sealed and Delivered
 in the Presence
of:
				 MIDA GROUP, LLC, a Florida limited

liability company

				
	  
				By:		  

							Judy K. Humbarger, Manager
							“Landlord”
				
	  
						
	(As to Landlord)						
			
					 ALLERGEN RESEARCH
 CORPORATION, a
California corporation

	  
				
				
					By:		  

 

									
	  
 (As to Tenant)
						    Printed Name:		  

 

							
					Title:		   

							“Tenant”

 EXHIBIT “D” 

Base Rent for Initial Term 
  

					
	 Year
	  	Monthly Amount	 
	 Year 1
	  	$	12,500.00	  
	 Year 2
	  	$	12,875.00	  
	 Year 3
	  	$	13,250.00	  
	 Year 4
	  	$	13,625.00	  
	 Year 5
	  	$	14,000.00	  
	 Year 6
	  	$	14,375.00	  
	 Year 7
	  	$	14,750.00	  
	 Year 8
	  	$	15,125.00	  
	 Year 9
	  	$	15,500.00	  
	 Year 10
	  	$	15,875.00	  

 EXHIBIT “E” 

Landlord’s Work 
 WORK TO
PREMISES 
  

	 	•	 	Demo all walls creating one large open space to deck 

  

	 	•	 	Service and provide industry standard A/C and rework duct 

  

	 	•	 	Leave three offices towards the front, paint and carpet 

 WORK TO PROJECT 

 

	 	•	 	Rework fire sprinkler system and alarm 

  

	 	•	 	Upgrade landscaping 

  

	 	•	 	Paint exterior 

  

	 	•	 	Seal and stripe the parking lot 

  

	 	•	 	Sub-Meter for power 

  

	 	•	 	Roof upgrades

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