Document:

<PAGE>

                                                                  EXHIBIT 10.1

                              CONSULTANT AGREEMENT

         THIS CONSULTANT AGREEMENT (the "Agreement") is effective as of the 5th
day of September, 2002 (the "Effective Date"), by and between Mark B. Chandler,
Ph.D. ("Consultant") and Luminex Corporation, a Delaware corporation (the
"Company").

         WHEREAS, the Company has entered into an Asset Purchase Agreement,
effective as of September 5, 2002, with Rules-Based Medicine, Inc., a Delaware
corporation and wholly owned subsidiary of the Company ("Seller"), and RBM
Acquisition, Inc., a Delaware corporation ("Buyer"), pursuant to which Buyer is
purchasing certain assets of Seller and assuming the liabilities of Seller
relating to the business (the "RBM Business") of developing and commercializing
testing services and reagent kit products for the pharmaceutical, diagnostics,
toxicology, epidemiology and biotechnology markets, generating and selling
access to a database of information from blood samples and other fluids or
tissues and determining the relevance of such information and establishing an
intellectual property position around the relationship of the information to
health and disease including diagnostics, prognostics and therapeutics (the
"Transaction");

         WHEREAS, Consultant has served as the President and Chief Executive
Officer of the Company pursuant to the terms of the Employment Agreement, dated
as of March 10, 2000 (the "Employment Agreement") and as a member of the Board
of Directors and serving in the capacity of Chairman; and

         WHEREAS, Consultant will resign from his employment with the Company
and in his capacity as a director effective September 5, 2002, enter into this
Agreement and shall become employed by Buyer.

         NOW, THEREFORE, in consideration of the foregoing and the covenants,
representations and agreements set forth below, the Company and Consultant
hereby agree as follows:

         1. Retention as Consultant. The Company hereby retains Consultant, and
Consultant hereby agrees to render services to the Company, upon the terms and
conditions contained in this Agreement. Consultant hereby confirms his
resignation as an officer and director of the Company effective as of September
5, 2002.

         2. Term of the Agreement. The term of this Agreement (the "Term") shall
commence on the Effective Date and shall terminate on the first anniversary of
the Effective Date.

         3. Services to be Provided by Consultant.

            3.1. Scope, Responsibilities and Duties. Consultant agrees to
         provide consulting services to the Company so that the Company may have
         the benefit of the experience and knowledge possessed by Consultant,
         including but not limited to meeting

<PAGE>

         with customers, providing technical advice on Company products and
         services, providing general business advice, marketing and strategic
         input, personnel support and such other matters as reasonably requested
         by the Board of Directors or the Chief Executive Officer of the Company
         (the "Services"). Such Services shall be performed at times and places
         selected by mutual agreement of the Company and Consultant within
         normal business hours, which services shall be reasonably related to
         Consultant's previous responsibilities with the Company prior to the
         date of this Agreement and only as reasonably needed by the Company.
         Consultant shall not be required to perform the Services at the offices
         of the Company except as Consultant may from time to time agree.
         Consultant shall not be expected to be available to perform such
         services on a daily basis, it being acknowledged that Consultant shall
         have substantial duties and responsibilities with respect to the RBM
         Business of Buyer and scheduling of any Services shall be subject to
         such duties and responsibilities. Consultant agrees to provide the
         Services from time to time as requested by the Board of Directors or
         the Chief Executive Officer of the Company upon reasonable advance
         notice. It shall be the duty of Consultant in rendering the Services to
         make such periodic reports to the Company relating to the Services as
         the Chief Executive Officer or the Board of Directors of the Company
         may, from time to time, reasonably request.

            3.2. Non-exclusivity. Subject to the provisions of Sections 7 and 9
         below, Consultant by reason of the obligations ascribed to him
         hereunder shall not be limited in any manner in accepting other
         employment and performing services for others, provided he fully
         performs his obligations hereunder.

         4. Compensation. As compensation for the Services to be provided by
Consultant to the Company, the Company shall pay to Consultant, and Consultant
agrees to accept the following:

            4.1. Cash Compensation. Consultant shall receive a fee of $350,000
         during the Term, payable in equal payments during the Term consistent
         with the timing of the payroll distributions of the Company.

            4.2. Stock Options. Consultant will be entitled to exercise his
         vested options for the purchase of the Company's common stock, $.001
         par value per share ("Common Stock"), which are set forth on Exhibit A
         attached hereto, for the lesser of (i) the life of the option or (ii)
         two (2) years from the date hereof. All unvested options to purchase
         Common Stock held by Consultant shall be terminated as of his last day
         of employment.

         Consultant shall not be entitled to any other compensation for the
Services to be provided hereunder, except as provided herein. The Company shall
not be responsible for withholding from the compensation payable to Consultant
any amounts for federal, state or local income taxes, social security or state
disability or unemployment insurance.

         5. Expenses. Upon receipt of itemized vouchers, expense account reports
and supporting documents submitted to the Company in accordance with the
Company's procedures then in effect, the Company shall reimburse Consultant for
all reasonable and necessary business

                                       2
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expenses (including travel and entertainment expenses) incurred ordinarily and
necessarily by Consultant in connection with the performance of Consultant's
duties hereunder.

         6. Termination. Termination pursuant to this Section, unless terminated
by Consultant pursuant to Section 6.2, shall become effective immediately upon
receipt by Consultant of written notice from the Company of such termination.

            6.1. Termination for Cause. The Company may terminate this Agreement
         for cause at any time without further obligation or liability to
         Consultant. A termination shall be for "cause" if Consultant (a)
         commits a criminal act involving moral turpitude or (b) commits a
         material breach of any of the covenants, terms and provisions hereof
         (including, but not limited to, failure to obey lawful and proper
         written directions delivered to Consultant by the Company's Chief
         Executive Officer or its Board of Directors regarding Services as set
         forth in Section 3.1), which breach shall continue after five (5) days
         (the "Notice Period") written notice from the Company describing such
         breach in reasonable detail. If the Notice Period is impracticable,
         then the Notice Period shall be reduced to such period of time as may
         be reasonable in light of circumstances, as determined by the Company
         in its reasonable discretion, and set forth in such notice.

            6.2. Termination Without Cause. Either the Company or Consultant may
         terminate this Agreement without cause and for any reason at any time.
         Upon a termination of this Agreement by the Company pursuant to this
         Section 6.2, Consultant shall be entitled to receive any remaining fees
         payable as provided in Section 4.1 during the remainder of the Term
         pursuant to the terms of this Agreement, such fees payable in equal
         payments during the remainder of the Term. Upon a termination of this
         Agreement by Consultant without cause pursuant to this Section 6.2,
         Consultant shall be entitled to all fees accrued hereunder through the
         date of termination with no further payment obligation on the part of
         the Company.

            6.3. Termination by Incapacity or Disability of Consultant. If
         Consultant shall become unable to fully perform the Services in
         accordance with the terms of this Agreement due to incapacity, ill
         health or disability for a consecutive period of 90 days, the Company
         may, at its option, terminate this Agreement. During any incapacity,
         ill health or disability and upon a termination of this Agreement by
         the Company pursuant to this Section 6.3, Consultant shall be entitled
         to receive any remaining fees payable as provided in Section 4.1 during
         the remainder of the Term pursuant to the terms of this Agreement, such
         fees payable in equal payments during the remainder of the Term.

            6.4. Death of Consultant. Upon the death of Consultant, Consultant's
         estate shall be entitled to receive any remaining fees payable as
         provided in Section 4.1 during the remainder of the Term pursuant to
         the terms of this Agreement, such fees payable in equal payments during
         the remainder of the Term.

            6.5. Survival. It is understood that termination of this Agreement
         shall not relieve a party hereto from any liability which, at the time
         of such termination, has already accrued to the other party. The
         following provisions and all subsections therein

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         shall survive any expiration or termination of this Agreement: Sections
         5, 6, 7, 8, 9, 10.2, 11, 12, 13, 14, 15, 16, 17 and 18. Except as
         otherwise expressly provided in this Section 6, all other rights and
         obligations of the parties shall terminate upon termination of this
         Agreement.

         7. Confidential Information.

            7.1. Acknowledgment of Proprietary  Interest. As between the
         parties, Consultant agrees that all Confidential Information is a
         valuable, special and unique asset of the Company's business (and may
         constitute "trade secrets" under the Uniform Trade Secrets Act and
         Texas state law), access to and knowledge of which are essential to the
         performance of Consultant's duties hereunder. Consultant acknowledges
         the proprietary interest of the Company in all Confidential
         Information. Consultant agrees that all Confidential Information
         learned by Consultant in connection with his provision of Services or
         otherwise, whether developed by Consultant alone or in conjunction with
         others or otherwise, is and shall remain the exclusive property of the
         Company. Consultant acknowledges and agrees that his disclosure or use
         of any Confidential Information in violation of this Section 7 will
         result in irreparable injury and damage to the Company.

            7.2. Confidential Information Defined. "Confidential Information"
         means all confidential and proprietary information of the Company,
         written, oral or computerized, as it may exist from time to time,
         including without limitation (i) information derived from reports,
         investigations, experiments, research and work in progress, (ii)
         methods of operation, (iii) market data, (iv) technology, hardware,
         proprietary computer programs and code (in object code and source code
         format) including without limitation the xMap proprietary system and
         consumables, (v) drawings, designs, plans and proposals, (vi) marketing
         and sales programs, (vii) client and supplier lists and any other
         information about the Company's relationships with others, (viii)
         historical financial information and financial projections, (ix)
         network and system architecture, (x) all other formulae, patterns,
         devices or compilations, concepts, ideas, materials and information
         prepared or performed for or by the Company, and (xi) all information
         related to the business plan, business, products, purchases or sales of
         the Company or any of its suppliers and customers, other than
         information that is publicly available. "Confidential Information"
         shall not include information relating to the RBM Business not
         otherwise covered by the preceding sentence, except to the extent such
         information is licensed to Buyer.

            7.3. Covenant Not To Divulge Confidential Information. The Company
         is entitled to prevent the disclosure of Confidential Information. As a
         portion of the consideration for the hiring of Consultant and for the
         compensation being paid to Consultant by the Company, Consultant shall,
         at all times during the Term and thereafter, hold in strict confidence
         and shall not disclose or allow to be disclosed to any person, firm or
         corporation, other than to persons engaged by the Company to further
         the business of the Company, and not to use except in the pursuit of
         the business of the Company, the Confidential Information, without the
         prior written consent of the Company. This Section 7 shall survive and
         continue in full force and effect in accordance

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         with its terms after, and will not be deemed to be terminated by, any
         termination of this Agreement.

            7.4. Return of Materials at Termination. In the event of any
         termination of this Agreement for any reason, Consultant shall promptly
         deliver to the Company all property of the Company, including without
         limitation all documents, data and other information containing,
         derived from or otherwise pertaining to Confidential Information.
         Consultant shall not take or retain any property of the Company,
         including without limitation any documents, data or other information,
         or any reproduction or excerpt thereof, containing, derived from or
         pertaining to any Confidential Information. The obligation of
         confidentiality set forth in this Section 7 shall continue
         notwithstanding Consultant's delivery of such documents, data and
         information to the Company.

         8. Inventions; Assignment.

            8.1. Inventions Defined. All rights to discoveries, inventions,
         improvements, designs, work product and innovations (including without
         limitation all data and records pertaining thereto) that relate to the
         business of the Company (excluding discoveries, inventions,
         improvements, designs, work product and innovations directly relating
         to the RBM Business), whether or not specifically within Consultant's
         duties or responsibilities and whether or not patentable, copyrightable
         or reduced to writing, that Consultant may discover, invent, create or
         originate during the term of his consulting relationship with the
         Company, was discovered, invented, created or originated during his
         employment with the Company or otherwise, and for a period of six (6)
         months thereafter, either alone or with others and whether or not
         during working hours or using the facilities of the Company
         ("Inventions"), shall be the exclusive property of the Company.
         Consultant shall promptly disclose all Inventions to the Company, shall
         execute at the request of the Company any assignments or other
         documents the Company may deem necessary to protect or perfect its
         rights therein, and shall assist the Company, at the Company's expense,
         in obtaining, defending and enforcing the Company's rights therein.
         Consultant hereby appoints the Company as his attorney-in-fact to
         execute on his behalf any assignments or other documents deemed
         necessary by the Company to protect or perfect its rights to any
         Inventions.

            8.2. Covenant to Assign and Cooperate. Without limiting the
         generality of the foregoing, Consultant shall assign and transfer, and
         does hereby assign and transfer, to the Company worldwide right, title
         and interest of Consultant in the Inventions. Consultant agrees that
         the Company may file copyright registrations and apply for and receive
         patents (including without limitation Letters Patent in the United
         States) for the Inventions in the Company's name in such countries as
         may be determined solely by the Company. Consultant shall communicate
         to the Company all facts known to Consultant relating to the Inventions
         and shall cooperate with the Company's reasonable requests in
         connection with vesting title to the Inventions and related copyrights
         and patents exclusively in the Company and in connection with
         obtaining, maintaining, protecting and enforcing the Company's
         exclusive copyrights and patent rights in the Inventions. Consultant
         further acknowledges and agrees that all Inventions, original works of

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        authorship, developments, concepts, know-how, improvements or trade
        secrets which are made by Consultant (solely or jointly with Company),
        relating to the business of the Company but excluding those directly
        related to the RBM Business, within the scope of and during the Term of
        this Agreement, are "works made for hire" under 17 U.S.C. ss. 101 of the
        U.S. Copyright Act of 1976, and are compensated by such amounts paid to
        Consultant under this Agreement, unless regulated otherwise by the
        mandatory law of the state of Texas. In the event that any such
        Invention is deemed by a court of competent jurisdiction not to be a
        "work made for hire", this Agreement shall operate as an irrevocable
        assignment by Consultant to the Company of all right, title and interest
        in and to such Inventions, including without limitation all intellectual
        property rights therein. The Company shall not be required to designate
        Consultant as author of any Invention, and Consultant shall have no
        right to exercise any economic rights to the Inventions. Without
        limiting the foregoing, Consultant shall not have the right to and will
        not reproduce, adapt, modify, publish, distribute, sublicense, publicly
        perform or communicate, translate, lease, import and otherwise exploit
        the Inventions, except as expressly authorized by the Company in
        writing. If, during the Term of this Agreement, Consultant incorporates
        into a Company product, process or instrument, an Invention owned by
        Consultant or in which Consultant has an interest, the Company is hereby
        granted and shall have a non-exclusive, royalty-free, irrevocable,
        perpetual, worldwide license (with the right to sublicense through
        multiple tiers of sublicensees) to make, have made, copy, modify, make
        derivative works of, use, sell and otherwise distribute such Invention
        as part of or in connection with such product, process or instrument
        without Consultant's prior written consent.

            8.3. Successors and Assigns. Consultant's obligations under this
        Section 8 shall inure to the benefit of the Company and its successors
        and assigns and shall survive the expiration of the term of this
        Agreement for such time as may be necessary to protect the proprietary
        rights of the Company in the Inventions.

            8.4. Consideration and Expenses. Consultant shall perform his
        obligations under this Section 8 at the Company's expense, but without
        any additional or special compensation therefor.

        9.  Non-competition.

            9.1. Covenant Not to Compete. Consultant acknowledges that during
        his employment he received, and during the Term the Company has agreed
        to provide to him, and he shall receive from the Company, special
        training and knowledge, including without limitation the Confidential
        Information. Consultant acknowledges that the Confidential Information
        is valuable to the Company and, therefore, its protection and
        maintenance constitutes a legitimate interest to be protected by the
        Company by the enforcement of the covenant not to compete contained in
        this Section 9. Consultant also acknowledges that such covenant not to
        compete is ancillary to other enforceable agreements of the parties,
        including without limitation the agreements regarding Confidential
        Information in Section 7. Therefore, Consultant shall not directly or
        indirectly:

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                 (i) for a period equal to the later of (A) one year following
        the date of the termination of this Agreement or (B) two years from the
        date hereof (unless extended pursuant to the terms of this Section 9)
        engage, alone or as a stockholder, partner, member, manager, director,
        officer, employee of or consultant to, any entity other than the Company
        or its affiliate in any business activities that were conducted by the
        Company as of the date hereof (the "Designated Industry") other than the
        RBM Business; or

                 (ii) for a period equal to the later of (A) one year following
        the date of the termination of this Agreement or (B) two years from the
        date hereof (unless extended pursuant to the terms of this Section 9)
        (1) induce or attempt to induce any employee of the Company to leave the
        employ of the Company, (2) in any way interfere with the relationship of
        the Company and any employee, as of the date hereof and/or during the
        Term of this Agreement, of the Company, (3) employ, or otherwise engage
        as an employee, independent contractor, or otherwise, any employee as of
        the date hereof and/or during the Term of this Agreement, of the
        Company, or (4) induce or attempt to induce any customer, supplier,
        licensee, or business relation of the Company to cease doing business
        with the Company, or in any way interfere with the relationship between
        any customer, supplier, licensee, or business relation of the Company.

            9.2. Exclusion. Notwithstanding the provisions of this Section 9,
        Employee's non-competition obligations hereunder shall not preclude
        Employee from owning less than one percent of the voting power or
        economic interest in any publicly traded corporation conducting business
        activities in the Designated Industry.

            9.3. No Offset. The representations and covenants contained in this
        Section 9 on the part of Consultant shall be construed as ancillary to
        and independent of any other provision of this Agreement, and the
        existence of any claim (monetary or otherwise) or cause of action of
        Consultant against the Company or any officer, director or stockholder
        of the Company, whether predicated on this Agreement or otherwise, shall
        not constitute a defense to the enforcement by the Company of the
        covenants of Consultant contained in this Section 9.

            9.4. Extension and Survival. If Consultant violates any covenant
        contained in this Section 9, the Company shall not, as a result of such
        violation be deprived of the benefit of the full period of any such
        covenant. Accordingly, the covenants of Consultant contained in this
        Section 9 shall be deemed to have durations as specified in Section 9.1,
        which periods shall be extended by a number of days equal to the sum of
        the total number of days Consultant is found by a court of competent
        jurisdiction to be in violation of any of the covenants contained in
        this Section 9. This Section 9 shall survive and continue in full force
        and effect in accordance with its terms after, and will not be deemed to
        be terminated by, any termination of this Agreement.

                                       7

<PAGE>

            9.5. Severability. If at any time the provisions of this Section 9
        are determined to be invalid or unenforceable by reason of being vague
        or unreasonable as to area, duration or scope of activity, this Section
        9 shall be considered divisible and shall be immediately amended to only
        such area, duration or scope of activity as shall be determined to be
        reasonable and enforceable by the court or other body having
        jurisdiction over the matter; and Consultant agrees that this Section 9
        as so amended shall be valid and binding as though any invalid or
        unenforceable provision had not been included herein.

            9.6. Business of the Company. For purposes of Sections 8 and 9
        hereof, "the business of the Company" and the "business activities that
        were conducted by the Company" are defined as (i) Consultant's actual
        knowledge of the business of the Company as of the date hereof and (ii)
        the description set forth in the Company's Annual Report on Form 10-K
        for the year ended December 31, 2001 and as subsequently set forth in
        any periodic or other report filed by the Company with the Securities
        and Exchange Commission as of the date hereof.

        10. Relationship of the Parties.

            10.1. Consultant enters into this Agreement as, and shall continue
        to be, an independent contractor. The parties agree that no employment
        relationship, partnership, joint venture or other association shall be
        deemed created by this Agreement. Under no circumstances shall
        Consultant look to the Company as his employer, or as a partner, agent,
        or principal. Consultant shall not be entitled to any benefits accorded
        to the Company's employees including, without limitation, workers'
        compensation, disability insurance, vacation or sick pay.

            10.2. Consultant shall have the entire responsibility to discharge
        any and all of his obligations under federal, state or local laws,
        regulations or orders now or hereafter in effect, relating to taxes,
        unemployment compensation or insurance, social security, workers'
        compensation, disability pensions and tax withholdings (the "Tax
        Obligations"). Consultant hereby agrees to indemnify and hold the
        Company harmless for any and all claims, losses, costs, fees,
        liabilities, damages or injuries suffered by the Company arising out of
        Consultant's failure to properly discharge the Tax Obligations.

        11. Resignation of Employment. The parties hereby agree that Consultant
has voluntarily resigned his employment with the Company pursuant to Section
6(b)(iii) of the Employment Agreement and that the Employment Agreement is
hereby terminated.

        12. Arbitration.

            12.1. Any dispute regarding any aspect of this Agreement or any act
        which would violate any provision in this Agreement (hereafter referred
        to as "arbitrable dispute") shall be resolved by an experienced
        arbitrator licensed to practice law in the State of Texas and selected
        in accordance with the rules of the American Arbitration

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        Association, as the exclusive remedy for such dispute. Judgment on any
        award rendered by such arbitrator may be entered in any court having
        proper jurisdiction.

            12.2. Should Consultant or the Company institute any legal action or
        administrative proceeding regarding any dispute or matter covered by
        this Section by any method other than said arbitration, the responding
        party shall be entitled to recover from the other party all damages,
        costs, expenses and attorneys' fees incurred as a result of such
        action.

        13. Severability and Governing Law.

            13.1. Should any of the provisions in this Agreement be declared or
        be determined to be illegal or invalid, all remaining parts, terms or
        provisions shall be valid, and the illegal or invalid part, term or
        provision shall be deemed not to be a part of this Agreement.

            13.2. This Agreement is made and entered into in the State of Texas
        and shall in all respects be interpreted, enforced and governed under
        the laws of Texas without regard to the principles of conflicts of law.

        14. Proper Construction.

            14.1. The language of all parts of this Agreement shall in all cases
        be construed as a whole according to its fair meaning, and not strictly
        for or against any of the parties.

            14.2. As used in this Agreement, the term "or" shall be deemed to
        include the term "and/or" and the singular or plural number shall be
        deemed to include the other whenever the context so indicates or
        requires.

            14.3. The paragraph headings used in this Agreement are intended
        solely for convenience of reference and shall not in any manner amplify,
        limit, modify or otherwise be used in the interpretation of any of the
        provisions hereof.

        15. Entire  Agreement. This Agreement is the entire agreement between
Consultant and the Company and fully supersedes any and all prior agreements or
understandings between the parties pertaining to its subject matter, including
without limitation the Employment Agreement.

        16. Notices. All notices, requests, demands and other communications
called for or contemplated under this Agreement shall be in writing and shall be
deemed to have been duly given when personally delivered, on the date of
transmission if sent by facsimile, on the third day after mailing if mailed to
the party to whom notice is to be given, by first class mail, postage prepaid,
and properly addressed as follows:

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             If to the Company:         Luminex Corporation
                                        12212 Technology Drive
                                        Austin, TX  78727-6115
                                        Attention:  General Counsel

             If to Consultant:          Mark B. Chandler, Ph.D.
                                        4 Niles Road
                                        Austin, TX 78703

        17. Amendments. This Agreement may not be amended, supplemented,
canceled, or discharged except by written instrument executed by the parties
hereto.

        18. Waivers. All waivers hereunder shall be in writing. No waiver by any
party hereto of any breach or anticipated breach of any provision of this
Agreement by any other party shall be deemed a waiver of any other
contemporaneous, preceding, or succeeding breach or anticipated breach, whether
or not similar, on the part of the same or any other party.

                  [Remainder of Page Intentionally Left Blank]

                                       10

<PAGE>

         IN WITNESS WHEREOF, the parties hereto have hereby executed this
Agreement as of the day and year first written above.

                                       LUMINEX CORPORATION

 /s/  Mark B. Chandler, Ph.D.          By: /s/  Harriss T. Currie
-------------------------------           --------------------------------------
Mark B. Chandler, Ph.D.                   Name: Harriss T. Currie
                                                --------------------------------
                                          Title: Acting Chief Financial Officer
                                                 -------------------------------

                                       11

<PAGE>

                                    EXHIBIT A

                      Common Stock Options of Mark Chandler

<TABLE>
<CAPTION>

                                           Exercise
          Grant          Shares Subject     Price           Vested         Unvested
           Date           to Option(1)     Per Share       Options(2)      Options(3)
        ---------         ------------     ---------       ----------      ----------
        <S>               <C>              <C>             <C>             <C>
        5/20/99             510,000        $   3.92          510,000              0
        3/15/00             100,000           17.00           80,555         19,445
        12/05/00              3,990         25.0625            2,327          1,663
        12/05/00            121,010         25.0625           70,589         50,421
        1/19/01              50,000         24.8125           26,388         23,612
        5/23/02              50,000            6.52            4,166         45,834
</TABLE>

------------

(1)      All options are non-qualified stock options except for the grant on
         12/05/00 for 3,990 which are ISOs.
(2)      As of September 5, 2002.
(3)      These options are terminated as of the date of this Agreement.

                                       12<PAGE>

                                                                  EXIHIBIT 10.2

                          MANAGEMENT SERVICES AGREEMENT

         THIS AGREEMENT (the "AGREEMENT") is made effective as of the 12th day
of August, 2002 (the "Effective Date"), between Luminex Corporation a Delaware
corporation (the "COMPANY") and Thomas W. Erickson ("ERICKSON").

                                  INTRODUCTION

         The Company and Erickson desire to enter into an agreement pursuant to
which Erickson will provide his services to the Company.

         NOW, THEREFORE, the parties agree as follows:

         1. Definitions

                (a) "Affiliate" means any person, firm, corporation,
         partnership, association or entity that, directly or indirectly or
         through one or more intermediaries, controls, is controlled by or is
         under common control with the Company.

                (b) "Cause" the occurrence of any of the following events:

                        (i) willful refusal by Erickson to follow a lawful
                direction of the Board of Directors of the Company, provided the
                direction is not materially inconsistent with the duties or
                responsibilities of Erickson's position as interim President and
                Chief Executive Officer of the Company, which refusal continues
                after the Board of Directors has again given the direction;

                        (ii) willful misconduct or reckless disregard of
                Erickson's duties or of the interest or property of the Company;

                        (iii) intentional disclosure by Erickson to an
                unauthorized person of Confidential Information or Trade Secrets
                (as such terms are defined in Section 5(b) below), which causes
                material harm to the Company;

                        (iv) any act by Erickson of fraud, material
                misappropriation, significant dishonesty, or act involving moral
                turpitude;

                        (v) conviction by Erickson of a felony; or

                        (vi) a material breach of this Agreement by Erickson
                shall occur, and Erickson fails to cure the breach within ten
                (10) days following the Company's giving prompt written notice
                of the breach specifying in detail the facts and circumstances
                constituting the breach.

<PAGE>

                (c) "Disability" means the inability of Erickson to perform the
        material duties of his position as interim President and Chief Executive
        Officer hereunder due to a physical, mental, or emotional impairment,
        for a ninety (90) consecutive day period or for aggregate of one hundred
        eighty (180) days during any three hundred sixty-five (365) day period.

                (d) "Good Reason" means the occurrence of all of the following:

                        (i) the Company materially breaches this Agreement or
                the Company demotes Erickson or assigns him to perform other
                duties other than those of the interim President and Chief
                Executive Officer, except as specifically set out in paragraph
                2(a) below;

                        (ii) Erickson gives written notice to the Company of the
                facts and circumstances constituting the breach within ten (10)
                days following the occurrence of the breach;

                        (iii) the Company fails to remedy the breach within ten
                (10) days following Erickson's written notice of the breach; and

                        (iv) Erickson terminates the engagement and this
                Agreement within ten (10) days following the Company's failure
                to remedy the breach.

        2. Terms and Conditions of Engagement.

                (a) Engagement. Erickson shall be deemed an employee of the
        Company as of August 12, 2002. Beginning on the date that the Company
        receives the resignation of Mark B. Chandler, Ph.D., Erickson shall be
        the interim President and Chief Executive Officer of the Company,
        subject to the terms and conditions hereof, and shall perform the duties
        of that position. Notwithstanding any other provision hereof, in the
        event the Company appoints another person as President and Chief
        Executive Officer during the Term (defined in Section 4 hereof), and
        removes Erickson as interim President and Chief Executive Officer, the
        Board of Directors of the Company may cause Erickson to perform other
        management or management advisory duties to the Company which the Board
        of Directors may reasonably request for the remainder of the Term; and
        in the event the Company appoints another person as interim President
        and Chief Executive Officer during the Term, then (i) the Company shall
        be obligated to perform all of its obligations to Erickson under this
        Agreement unless the Company has terminated Erickson for cause; and (ii)
        Erickson may immediately cease rendering any services for the Company.

                (b) Benefits. Erickson shall receive substantially the same
        benefits as other executives of the Company, except that Erickson
        intends to opt out of the group medical plan the Company offers to its
        executives.

                                       2
<PAGE>

        3. Compensation.

                (a) Cash Compensation. For the month of August 2002, the Company
        shall pay to Erickson $35,984.85 for Erickson's services to the Company.
        Thereafter, the Company shall pay to Erickson $41,667 per month for
        Erickson's services hereunder. The Company shall pay the monthly cash
        compensation in substantially equal installments after the services are
        performed in accordance with the payroll policies of the Company. For
        any partial month during the term hereof, the Company shall pay Erickson
        after the services are performed cash compensation on a pro rata basis
        as set forth above.

                        (i) The Company will also pay Erickson $414.12 per month
                so that Erickson can continue to pay for coverage under his
                current medical plan.

                (b) Stock Options. Erickson shall be granted options to purchase
        an aggregate of 40,000 shares of the Company's Common Stock. The options
        shall vest and become immediately exercisable in accordance with the
        following schedule:

<TABLE>
<CAPTION>

                          DATE                             NUMBER OF SHARES
                          ----                             ----------------
                   <S>                                     <C>
                   September 30, 2002                            6,666
                   October 31, 2002                              6,666
                   November 29, 2002                             6,667
                   December 31, 2002                             6,667
                   January 31, 2002                              6,667
                   February 28, 2003                             6,667
</TABLE>

        The exercise price for each option will be the closing price of the
        Company's Common Stock on August 12, 2002. The option grants will be
        subject to the terms and conditions applicable to options granted under
        the Company's 2000 Long-Term Incentive Plan (the "Plan") and shall
        remain exercisable for a period of ten (10) years following the date of
        grant. Upon termination of Erickson's employment (i) by the Company for
        Cause, or by Employee, without Good Reason, no further options shall
        vest after the date of termination, but all options vested prior to the
        date of termination shall remain vested and exercisable for a period of
        ten (10) years following the date of grant, and (ii) for any other
        reason by the Company or Erickson, all options shall automatically vest
        as of the date of termination and be exercisable for a period of ten
        (10) years following the date of grant. Erickson will be mailed a
        statement detailing his vested options by the 15th day following the
        close of each monthly vesting period. Erickson and the Company shall
        enter into a Stock Option Award Agreement that, notwithstanding the
        terms of the Plan, contains terms consistent with those set forth above.

                (c) Expenses. Erickson shall be entitled to be reimbursed in
        accordance with the policies of the Company, as adopted and amended from
        time to time, for all reasonable and necessary expenses incurred by
        Erickson in connection with the performance of Erickson's duties of
        employment hereunder. Such expense

                                       3
<PAGE>

        reimbursement to Erickson will include, without limitation:

                        (i) Erickson's reasonable business travel expenses
                between Dallas, Texas and Austin, Texas incurred in connection
                with the performance of his duties hereunder, including airfare,
                automobile expenses, lodging, and meals while he is performing
                services hereunder in Austin; and

                        (ii) Erickson's cell phone charges, fees and expenses
                incurred in connection with his employment hereunder.

        4. Term, Termination and Termination Payments.

                (a) Term. Unless sooner terminated pursuant to Section 4(b)
        hereof or extended by written agreement of the parties, the term of this
        Agreement shall commence as of August 12, 2002 and will end February 28,
        2003 (the "Term").

                (b) Termination. This Agreement and the engagement of Erickson
        by the Company hereunder may only be terminated: (i) by expiration of
        the term set forth in Section 4(a) hereof; (ii) by mutual agreement of
        the parties; (ii) by the Company without Cause; (iii) by Erickson for
        Good Reason; (iv) by the Company or Erickson due to the Disability of
        Erickson; or (v) by the Company for Cause. This Agreement shall also
        terminate immediately upon the death of Erickson. Notice of termination
        by any party shall be given prior to termination in writing and shall
        specify the basis for termination and the effective date of termination.
        Notice of termination for Cause by the Company shall specify the basis
        for termination for Cause. Except as provided in Section 4(c) and except
        as provided under the terms of the stock option agreements referred to
        in Section 3(b), Erickson shall not be entitled to any payments on
        benefits after termination of this Agreement, except for cash
        compensation pursuant to Section 3(a) accrued up to the date of
        termination and expenses required to be reimbursed pursuant to Section
        3(c) hereof.

                (c) Termination by the Company without Cause or by Erickson for
        Good Reason. In the event that Erickson is terminated by the Company
        without Cause or by Erickson for Good Reason, the Company will continue
        to pay Erickson the remainder of the cash compensation pursuant to
        Section 3(a) hereof for the remainder of the Term (determined without
        regard to the Company's premature termination thereof) on the same
        schedule as if Erickson had continued to perform services for such
        period and the stock options described in Section 3(b) shall be granted,
        vest and remain exercisable pursuant to the terms of the Agreement.

                (d) Survival. The covenants of Erickson in Section 5 hereof
        shall survive the termination of this Agreement and shall not be
        extinguished thereby.

                                       4
<PAGE>

        5. Covenant Not to Compete; Confidentiality and Trade Secrets; Ownership
           of Intellectual Property.

                (a) Covenant Not to Compete. Erickson shall not, during the Term
        of this Agreement and for a period of one (1) year immediately following
        the termination of this Agreement, or any extension thereof, for any
        reason, either directly or indirectly: (a) call on, solicit, or take
        away any of the Company's customers or potential customers about whom
        Erickson became aware as a result of Erickson's services to the Company,
        either for Erickson or for any other person or entity; or (b) solicit or
        take away or attempt to solicit or take away any of the Company's
        employees or contractors for Erickson or for any other person or entity.

                (b) Confidentiality and Trade Secrets. Erickson acknowledges and
        agrees that he has and/or will, during the Term of this Agreement,
        become privy to important proprietary, confidential business information
        and trade secrets that are the exclusive property of the Company. This
        information includes, without limitation, the methodology and processes
        of the chemical, hardware, software and firmware components of Luminex's
        xMAP(TM) technology that combines single- or variably-sized microspheres
        with differential fluorescent labeling to generate information useful
        for a variety of applications, business plans, marketing concepts,
        designs, proposals, product information, financial information,
        technology and costs, pricing information, customer lists, and key
        accounts, including their credit information and product wants and needs
        (the "Confidential Information"). This Confidential Information derives
        independent economic value, both actual and potential, from not being
        generally known to the public or to other persons who can obtain
        economic value from its disclosure and use. As the Company has always
        held the Confidential Information as proprietary, confidential trade
        secret information and has taken steps to insure that the Confidential
        Information is not disclosed outside of the Company, the Confidential
        Information constitutes "trade secrets" under the Uniform Trade Secrets
        Act and Texas state law. In light of the foregoing, Erickson therefore
        agrees that he will not at any time, now or in the future, share,
        disseminate, disclose, discuss or use the Confidential Information or
        Trade Secrets in any way.

                (c) Return of Company Property. Upon termination of this
        Agreement for any reason, as a prior condition to receiving any final
        compensation hereunder (including any payments pursuant to Section 4
        hereof), Erickson will promptly deliver to the Company all property
        belonging to the Company, including, without limitation, all
        Confidential Information and Trade Secrets (and all embodiments thereof)
        then in Erickson's custody, control or possession.

                (d) Survival. The covenants set forth herein will apply on and
        after the Effective Date hereof to any Confidential Information and
        Trade Secrets disclosed by the Company or developed by Erickson prior to
        or after the Effective Date hereof. The covenants restricting the use of
        Confidential Information will continue and be maintained by Erickson for
        a period of two years following the termination of this Agreement. The

                                       5
<PAGE>

        covenants restricting the use of Trade Secrets will continue and be
        maintained by Erickson following termination of this Agreement for so
        long as permitted by Texas law.

                (e) Ownership of Intellectual Property. Erickson hereby
        acknowledges and agrees that any and all copyrightable works authored by
        him in connection with the performance of services, alone or with
        others, during the Term of this Agreement, shall be deemed to have been
        specially ordered or commissioned for use as either a contribution to a
        collective work, as a translation, as a supplementary work, as a
        compilation, or as an instructional text and, as such, shall be deemed
        to be "works for hire" under the United States copyright laws from the
        inception of creation or such works. In the event that any such works
        shall be deemed by a court of competent jurisdiction not to be a "work
        made for hire," this Agreement shall operate as an irrevocable
        assignment by Erickson to the Company of all right, title and interest
        in and to such works, including without limitation, all worldwide
        copyright interests therein, in perpetuity. The fact that such
        copyrightable works are created by Erickson outside of the Company's
        facilities or other than during Erickson's working hours with the
        Company, shall not diminish the Company's rights with respect to such
        works which otherwise fall within this subsection. Erickson agrees to
        execute and deliver to the Company such further instruments or documents
        as may be requested by the Company in order to effectuate the purposes
        of this subsection.

                (f) Indemnification and Director and Officer Liability
        Insurance. The Company shall indemnify Erickson and Erickson's actions
        as interim President and Chief Executive Officer or in any other
        capacity in which he may render services to the Company to the maximum
        extent permitted by the laws of the state of incorporation of the
        Company. The Company will not, during the Term of this Agreement, amend
        its certificate of incorporation or by-laws so as to limit in any way
        the Company's indemnification or expense advancement obligations
        contained therein on the Effective Date. At all times during the term of
        this Agreement, the Company will cover Erickson, and name him as an
        insured to the extent necessary as a condition of coverage, under any
        director and officer liability policy it may maintain, in his capacity
        as the interim President and Chief Executive Officer or in any other
        capacity in which he may render services to the company.

        6. Contracts or Other Agreements with Former Employer or Business.

                Erickson hereby represents and warrants that he is not subject
        to any employment or consulting agreement or similar document, except as
        previously disclosed and delivered to the Company, with a former
        employer or with any business as to which Erickson's engagement by the
        Company and provision of services in the capacity contemplated would be
        a breach. For that reason, Erickson hereby represents and warrants that
        he is not subject to any agreement which prohibits him during a period
        of time which extends through the Term from any of the following: (i)
        providing services for the Company in the capacity contemplated by this
        Agreement; (ii) competing with, or in any way participating in a
        business which includes the Company's business; (iii) soliciting
        personnel of such former employer or other business to leave such former
        employer's

                                       6
<PAGE>

        employment or to leave such other business; or (iv) soliciting customers
        of such former employer or other business on behalf of another business.

        7. Remedies and Enforceability.

                Erickson agrees that the covenants and agreements contained in
        Section 5 hereof are of the essence of this Agreement; that each of such
        covenants is reasonable and necessary to protect and preserve the
        interests and properties of the Company; that irreparable loss and
        damage will be suffered by the Company should Erickson breach any of
        such covenants and agreements; that each of such covenants and
        agreements is separate, distinct and severable not only from the other
        of such covenants and agreements but also from the other and remaining
        provisions of this Agreement; that the unenforceability of any such
        covenant or agreement shall not affect the validity or enforceability of
        any other such covenant or agreements or any other provision or
        provisions of this Agreement; and that, in addition to other remedies
        available to it, the Company shall be entitled to seek specific
        performance of this Agreement and to seek both temporary and permanent
        injunctions to prevent a breach or contemplated breach by Erickson of
        any of such covenants or agreements.

        8. Notice.

                All notices, requests, demands and other communications required
        hereunder shall be in writing and shall be deemed to have been duly
        given if delivered or if mailed, by United States certified or
        registered mail, prepaid to the party to which the same is directed at
        the following addresses (or at such other addresses as shall be given in
        writing by the parties to one another):

        If to the Company:                   Luminex Corporation
                                             12212 Technology Blvd.
                                             Austin, TX 78727
                                             Attn: General Counsel

        If to Erickson:                      Thomas Erickson
                                             3106 Greenbrier Drive
                                             Dallas, TX 75225

        Notices delivered in person shall be effective on the date of delivery.
        Notices delivered by mail as aforesaid shall be effective upon the
        third calendar day subsequent to the postmark date hereof.

        9. Miscellaneous.

                (a) Assignment. The rights and obligations of the Company under
        this Agreement shall inure to the benefit of the Company's successors
        and assigns. This Agreement may be assigned by the Company to any legal
        successor to the Company's business or to an entity which purchases all
        or substantially all of the assets of the

                                       7
<PAGE>

        Company, but not otherwise without the prior written consent of
        Erickson. In the event the Company assigns this Agreement as permitted
        by this Agreement and Erickson remains engaged by the assignee, the
        "Company" as defined herein will refer to the assignee and Erickson will
        not be deemed to have terminated the engagement hereunder until Erickson
        terminates the engagement from the assignee. Erickson may not assign
        this Agreement.

                (b) Waiver. The waiver by the Company of any breach of this
        Agreement by any party shall not be effective unless in writing, and no
        such waiver shall constitute the waiver of the same or another breach on
        a subsequent occasion.

                (c) Governing Law. This Agreement shall be governed by and
        construed in accordance with the internal laws of the State of Texas.
        The parties agree that any appropriate state or federal court located in
        Austin, Texas shall have jurisdiction of any case or controversy arising
        under or in connection with this Agreement and shall be a proper forum
        in which to adjudicate such case or controversy. The parties consent to
        the jurisdiction of such courts.

                (d) Entire Agreement. This Agreement embodies the entire
        agreement of the parties hereto relating to the subject matter hereof
        and supersedes all oral agreements, and to the extent inconsistent with
        the terms hereof, all other written agreements.

                (e) Amendment. This Agreement may not be modified, amended,
        supplemented or terminated except by a written instrument executed by
        the parties hereto.

                (f) Severability. Each of the covenants and agreements
        hereinabove contained shall be deemed separate, severable and
        independent covenants, and in the event that any covenant shall be
        declared invalid by any court of competent jurisdiction, such invalidity
        shall not in any manner affect or impair the validity or enforceability
        of any other part or provision of such covenant or of any other covenant
        contained herein.

                (g) Captions and Section Headings. Except as set forth in
        Section 1 hereof, captions and section headings used herein are for
        convenience only and are not a part of this Agreement and shall not be
        used in construing it.

      [Remainder of page intentionally left blank; signature page follows]

                                       8
<PAGE>

IN WITNESS WHEREOF, the Company and Erickson have each executed and delivered
this Agreement as of the date first shown above.

                                         COMPANY:

                                         LUMINEX CORPORATION

                                         By:   /s/  Harriss T. Currie
                                             -----------------------------------

                                             Acting Chief Financial Officer
                                             ----------------------------------

                                         ERICKSON:

                                           /s/  Thomas W. Erickson
                                         ---------------------------------------
                                         Thomas W. Erickson

                                       9

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