Document:

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                                                                    EXHIBIT 10.8

                                                                  EXECUTION COPY

                            ASSET PURCHASE AGREEMENT

                                     BETWEEN

                         XANODYNE PHARMACEUTICALS, INC.,

                                 AAIPHARMA INC.

                                       AND

                                 AAIPHARMA, LLC

                                   ----------

                             Dated as of May 6, 2005

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                                TABLE OF CONTENTS

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<S>                                                                         <C>
ARTICLE I DEFINITIONS....................................................     1
   1.1   Certain Definitions.............................................     1
   1.2   Terms Defined Elsewhere in this Agreement.......................    14
   1.3   Other Definitional and Interpretive Matters.....................    16

ARTICLE II PURCHASE AND SALE OF ASSETS; ASSUMPTION OF LIABILITIES........    17
   2.1   Purchase and Sale of Assets.....................................    17
   2.2   Licenses........................................................    18
   2.3   Excluded Assets.................................................    25
   2.4   Assumption of Liabilities.......................................    26
   2.5   Excluded Liabilities............................................    26
   2.6   Cure Amounts....................................................    27
   2.7   Services Agreement, Manufacturing Agreement and Odyssey
         Co-Development Agreement........................................    27
   2.8   Further Conveyances and Assumptions.............................    27
   2.9   Bulk Sales Law..................................................    28

ARTICLE III CONSIDERATION................................................    28
   3.1   Consideration...................................................    28
   3.2   Royalties on Lifecycle Products.................................    28
   3.3   Products Option.................................................    29
   3.4   Option on Purchaser Developed Products..........................    33
   3.5   Odyssey.........................................................    34
   3.6   Disputed Statements.............................................    35
   3.7   Closing Date Inventory Adjustment...............................    36
   3.8   Adjustment for Excess Shipments.................................    38
   3.9   Payment of Purchase Price.......................................    38

ARTICLE IV CLOSING AND TERMINATION.......................................    38
   4.1   Closing Date....................................................    38
   4.2   Deliveries by Sellers...........................................    39
   4.3   Deliveries by Purchaser.........................................    39
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<S>                                                                         <C>
   4.4   Termination of Agreement........................................    40
   4.5   Payment of Development Costs....................................    41
   4.6   Procedure Upon Termination......................................    42
   4.7   Effect of Termination...........................................    42

ARTICLE V REPRESENTATIONS AND WARRANTIES OF SELLERS......................    42
   5.1   Organization and Good Standing..................................    42
   5.2   Authorization of Agreement......................................    42
   5.3   Board Approval and Recommendation...............................    43
   5.4   Conflicts; Consents of Third Parties............................    43
   5.5   Financial Statements; Projections...............................    44
   5.6   No Undisclosed Liabilities......................................    45
   5.7   Absence of Certain Developments.................................    45
   5.8   Taxes...........................................................    45
   5.9   Title to Purchased Assets.......................................    46
   5.10  Intellectual Property...........................................    46
   5.11  Regulatory Status...............................................    48
   5.12  Material Contracts..............................................    50
   5.13  Labor...........................................................    50
   5.14  Litigation......................................................    50
   5.15  Compliance with Laws............................................    51
   5.16  Environmental Matters...........................................    51
   5.17  Insurance.......................................................    52
   5.18  Inventories.....................................................    52
   5.19  Customer........................................................    52
   5.20  Product Warranty; Product Liability.............................    52
   5.21  Financial Advisors..............................................    53
   5.22  FDA Indications.................................................    53
   5.23  Laboratory Notebooks............................................    53
   5.24  No Other Representations and Warranties.........................    53

ARTICLE VI REPRESENTATIONS AND WARRANTIES OF PURCHASER...................    53
   6.1   Organization and Good Standing..................................    53
   6.2   Authorization of Agreement......................................    53
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<S>                                                                         <C>
   6.3   Conflicts; Consents of Third Parties............................    54
   6.4   Litigation......................................................    54
   6.5   Financial Advisors..............................................    54
   6.6   Financing.......................................................    54

ARTICLE VII BANKRUPTCY COURT MATTERS.....................................    55
   7.1   Approval of Break-Up Fee and Expense Reimbursement..............    55
   7.2   Bidding Procedures..............................................    56
   7.3   Non-Solicitation Period.........................................    56
   7.4   Bankruptcy Court Approval.......................................    56

ARTICLE VIII COVENANTS...................................................    57
   8.1   Access to Information...........................................    57
   8.2   Permitted Sellers...............................................    58
   8.3   Conduct of the Business Pending the Closing.....................    58
   8.4   Development of Darvocet-N XR and Lynxorb........................    59
   8.5   Rejection of Contracts..........................................    60
   8.6   Consents........................................................    60
   8.7   Regulatory Approvals............................................    60
   8.8   Further Assurances..............................................    61
   8.9   Non-Competition; Non-Solicitation; Confidentiality..............    62
   8.10  Preservation of Records.........................................    64
   8.11  Publicity.......................................................    64
   8.12  aaiPharma Name..................................................    64
   8.13  Cooperation with Financing......................................    65
   8.14  Returns, Rebates and Chargebacks................................    65
   8.15  Adverse Experience Reporting and Product Complaints.............    67
   8.16  Recalls.........................................................    67
   8.17  Inventory.......................................................    67
   8.18  Financial Statements............................................    67
   8.19  Differentiation of Products.....................................    68
   8.20  Resale Certificates.............................................    68
   8.21  Enforcement of Rights...........................................    68
   8.22  Laboratory Notebooks............................................    68
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<TABLE>
<S>                                                                         <C>
   8.23  Darvocet-N XR IDM...............................................    68

ARTICLE IX EMPLOYEES.....................................................    69
   9.1   Employment......................................................    69
   9.2   Indemnification.................................................    69

ARTICLE X CONDITIONS TO CLOSING..........................................    69
   10.1  Conditions Precedent to Obligations of Purchaser................    69
   10.2  Conditions Precedent to Obligations of Sellers..................    70
   10.3  Conditions Precedent to Obligations of Purchaser and Sellers....    70
   10.4  Frustration of Closing Conditions...............................    71

ARTICLE XI INDEMNIFICATION...............................................    71
   11.1  Survival of Representations and Warranties......................    71
   11.2  Indemnification.................................................    71
   11.3  Indemnification Procedures......................................    73
   11.4  Limitations on Indemnification for Breaches of Representations
         and Warranties..................................................    74
   11.5  Indemnity Escrows...............................................    75
   11.6  Tax Treatment of Indemnity Payments.............................    75

ARTICLE XII TAXES........................................................    76
   12.1  Transfer Taxes..................................................    76
   12.2  Prorations......................................................    76
   12.3  Purchase Price Allocation.......................................    76
   12.4  Cooperation on Tax Matters......................................    77

ARTICLE XIII MISCELLANEOUS...............................................    78
   13.1  Expenses........................................................    78
   13.2  Specific Performance............................................    78
   13.3  Submission to Jurisdiction; Consent to Service of Process.......    78
   13.4  Waiver of Right to Trial by Jury................................    78
   13.5  Entire Agreement; Amendments and Waivers........................    79
   13.6  Governing Law...................................................    79
   13.7  Notices.........................................................    79
   13.8  Severability....................................................    80
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<S>                                                                         <C>
   13.9  Binding Effect; Assignment......................................    80
   13.10 Non-Recourse....................................................    80
   13.11 Time of Essence.................................................    81
   13.12 Counterparts....................................................    81
</TABLE>

Schedules
1.1(a)      Darvocet-N XR DDM, Darvocet-N XR Product and Lynxorb Product
1.1(b)      Inventory
1.1(c)      Knowledge of Sellers
1.1(d)      Marketed Products
1.1(e)      Marketing Authorizations
1.1(f)      Odyssey Patents and Odyssey Product
1.1(g)      Pipeline Products
1.1(h)      ProSorb Patents
1.1(i)      Purchased Contracts
1.1(j)      Purchased DMFs
1.1(k)      Purchased INDs
1.1(1)      Purchased Intellectual Property
2.7(i)      Additional Manufacturing Agreement Terms
2.7(ii)     Additional Services Agreement Terms
5.1         Good Standing
5.4(b)      Consents
5.5(c)      Exceptions to SEC Filings
5.7         Absence of Certain Developments
5.8         Taxes
5.9         Title to Purchased Assets
5.11        Regulatory Status
5.10        Intellectual Property
5.12        Material Contracts
5.14        Litigation
5.15        Compliance with Laws
5.16        Environmental Matters
5.17        Insurance
5.18        Inventory Estimate
5.19(a)     Customers
5.19(b)     Negative Customer Events
5.20        Product Warranty
5.21        Sellers Financial Advisors
6.5         Purchaser Financial Advisors
8.3         Conduct of the Business
8.5         Rejection of Contracts
8.14(a)(ii) Returned Marketed Products
9.1         Employees
10.3(e)     Closing Consents

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Exhibits

A  Bill of Sale
B  Assumption Agreement
C  Indemnity Escrow Agreement
D  Trademark Assignment Agreement
E  Manufacturing Agreement Term Sheet
F  Bidding Procedures
G  Services Agreement Term Sheet
H  Sale Order
I  Bidding Procedures Order
J  Product Transfer of Ownership Letters to the FDA

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                            ASSET PURCHASE AGREEMENT

          ASSET PURCHASE AGREEMENT, dated as of May 6, 2005 (this "Agreement"),
between Xanodyne Pharmaceuticals, Inc., a Delaware corporation ("Purchaser"),
aaiPharma Inc., a Delaware corporation ("Parent"), and aaiPharma, LLC, a
Delaware limited liability company ("LLC" and, together with Parent, "Sellers").

                                   WITNESSETH:

          WHEREAS, Sellers intend to commence chapter 11 cases in the United
States Bankruptcy Court for the District of Delaware (the "Bankruptcy Court")
(such cases, the "Chapter 11 Case") and shall be debtors-in-possession under
chapter 11 of title 11 of the United States Code, 11 U.S.C. Section 101 et seq.
(the "Bankruptcy Code");

          WHEREAS, Sellers desire to sell, transfer and assign to Purchaser or
its designated Affiliate or Affiliates, and Purchaser desires to (or to cause
its designated Affiliate or Affiliates to) acquire and assume from Sellers,
pursuant to Sections 363 and 365 of the Bankruptcy Code, all of the Purchased
Assets and Assumed Liabilities, all as more specifically provided herein; and

          WHEREAS, certain terms used in this Agreement are defined in Section
1.1;

          NOW, THEREFORE, in consideration of the premises and the mutual
covenants and agreements hereinafter contained, the parties hereby agree as
follows:

                                    ARTICLE I

                                   DEFINITIONS

     1.1 Certain Definitions.

          For purposes of this Agreement, the following terms shall have the
meanings specified in this Section 1.1:

          "AAIDS" means AAI Development Services, a division of Parent.

          "AAI IP" means all Intellectual Property owned and primarily used by
Sellers or their Affiliates in connection with any business other than the
Business, the Pipeline Products or the New Products, but exclusive of the
Purchased Intellectual Property.

          "AAI Trademarks" means the trademarks "aaiPharma," "AAI Development
Services," and "AAI," the aaiPharma and AAI DS corporate logos and the trade
names of Sellers, including the words "AAI" and "AAI Development Services"
together with variations and derivatives thereof and any other logos, symbols,
trademarks, trade names or service marks of Sellers or their respective
Affiliates including, except for the licenses granted thereto, the ProSorb
Trademark, but excluding the Purchased Trademarks.

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          "Accountant" means an accounting firm of national reputation
(excluding each of Purchaser's and Sellers' respective regular outside
accounting firms) as may be mutually acceptable to Purchaser and Sellers;
provided, however, that in the event that Purchaser and Sellers are unable to
agree on such an accounting firm within ten (10) Business Days after the date
the Accountant is required to be engaged pursuant to Section 3.6, then Sellers
shall within ten (10) Business Days thereafter deliver to Purchaser a listing of
three other accounting firms of national reputation and Purchaser shall, within
ten (10) Business Days after receipt of such list, select one of such three
accounting firms as the Accountant.

          "Affiliate" means, with respect to any Person, any other Person that,
directly or indirectly through one or more intermediaries, controls, or is
controlled by, or is under common control with, such Person, and the term
"control" (including the terms "controlled by" and "under common control with")
means the possession, directly or indirectly, of the power to direct or cause
the direction of the management and policies of such Person, whether through
ownership of voting securities, by contract or otherwise.

          "Alternative Transaction" means (a) the sale (whether by stock sale,
merger, consolidation or otherwise) of all or a substantial portion of the
capital stock of Sellers, (b) the sale of all or any of the Purchased Assets
pursuant to the Bidding Procedures, or (c) a transaction or series of
transactions outside or independent of the Bidding Procedures that result in the
Sellers realizing not less than an aggregate of $75,000,000 in cash and/or fair
market value of debt and/or equity securities (such fair market value to be
determined by the Bankruptcy Court or, if Sellers shall not then be the subjects
of a Chapter 11 Case, then jointly by Sellers and Purchaser or, failing such
joint determination, by an independent nationally recognized investment banking
firm jointly selected by Sellers and Purchaser or, failing such joint selection,
by such an independent nationally recognized investment banking firm selected by
two other investment banking firms selected one each by Sellers and Purchaser)
from the sale or transfer of Purchased Assets, in each case to a Person other
than Purchaser, excluding the sale of Inventory in the Ordinary Course of
Business.

          "ANDA" means an abbreviated new drug application.

          "APAP" means acetaminophen.

          "Applicable Laws" means all binding laws, treaties, statutes,
ordinances, decrees, rules, injunctions, writs, regulations, Orders,
authorizations and permits as all of the preceding may be in effect and
interpreted on the date of this Agreement, in each case relating to, or of any
Governmental Body having jurisdiction over, the Business the Purchased Assets,
the Licensed Assets, Sellers or Purchaser, as the case may be.

          "Approval Motion" means the motion, acceptable to Purchaser in its
reasonable discretion, to be filed with the Bankruptcy Court by Sellers no later
than one (1) day following the commencement of the Chapter 11 Case seeking
approval of the (a) the Bidding Procedures Order (including the Bidding
Procedures) and (b) the Sale Order.

          "Azathioprine ANDA" means ANDA 75-252.

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          "Azathioprine Copyrights" means Copyrights in all advertising,
marketing and promotional materials in any stage of development owned by Sellers
that are used or intended for use in connection with the Azathioprine Product.

          "Azathioprine Know How" means all Know How necessary or useful in
connection with the Azathioprine Product.

          "Azathioprine Product" means the 50 mg azathioprine product marketed
pursuant to the Azathioprine ANDA, including bioequivalents.

          "Azathioprine Product Assets" means the Azathioprine ANDA,
Azathioprine Copyrights (but exclusive of any portions of advertising or
marketing and promotional materials describing the business of Sellers or
incorporating the AAI Trademarks and any variations thereof and related logos or
symbols), and the Azathioprine Know How.

          "Bidding Procedures" means those bidding procedures set forth in
Exhibit F attached hereto.

          "Bidding Procedures Order" means the order of the Bankruptcy Court in
the form attached hereto as Exhibit I, including such changes thereto requested
or approved by Purchaser in its reasonable discretion, which changes shall in no
event be adverse to Purchaser.

          "Business" means the business of Sellers, as currently conducted, of
marketing, promoting, distributing, and selling the Marketed Products, but
excluding all other business of Sellers and their Affiliates, including AAI DS.

          "Business Day" means any day of the year on which national banking
institutions in New York are open to the public for conducting business and are
not required or authorized to close.

          "Break-Up Fee" means the fee to be paid by Sellers to Purchaser in
accordance with the provisions of Section 7.1 hereof.

          "Calcitriol ANDA" means ANDA 75-766.

          "Closing Date Inventory" means the quantities of each item of
Inventory as of the Closing Date.

          "Code" means the Internal Revenue Code of 1986, as amended.

          "Contract" means any contract, agreement, indenture, note, bond, loan,
instrument, lease, commitment or other arrangement or agreement, whether written
or oral.

          "Copyrights" means all copyrights, works of authorship, and
copyrightable works, and all registrations, applications, and renewals therefor.

          "Darvocet-N Suspension Know How" means all Know How necessary or
useful in connection with the Darvocet-N Suspension Product and owned by
Sellers, which, for the

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avoidance of doubt, excludes any Know How licensed from Eli Lilly and Company
that is the subject of the Assignment, Transfer and Assumption Agreement dated
as of February 18, 2002 between NeoSan Pharmaceuticals, Inc. and Eli Lilly and
Company referenced on Schedule 1.1(i).

          "Darvocet-N Suspension Product" means the product identified as such
in Schedule 1.1(a).

          "Darvocet-N XR IDM" means the invention disclosure memorandum
identified in Schedule 1.1(a) and the invention described therein.

          "Darvocet-N XR Know How" means all Know How necessary or useful in
connection with the Darvocet-N XR Product and owned by Sellers, which, for the
avoidance of doubt, excludes any Know How licensed from Eli Lilly and Company
that is the subject of the Assignment, Transfer and Assumption Agreement dated
as of February 18, 2002 between NeoSan Pharmaceuticals, Inc. and Eli Lilly and
Company referenced on Schedule 1.1(i).

          "Darvocet-N XR Product" means the product identified as such in
Schedule 1.1 (a).

          "DEA" means the United States Drug Enforcement Administration.

          "Derivative Darvocet Product" means the product identified as such in
Schedule 1.1(a).

          "Derivative Lynxorb Product" means the product identified as such in
Schedule 1.1(a).

          "Employee" means all individuals, as of the date hereof, who are
employed by Sellers in connection with the Business, together with individuals
who are hired in respect of the Business after the date hereof.

          "Environmental Costs and Liabilities" means, with respect to any
Person, all liabilities, obligations, responsibilities, Remedial Actions,
losses, damages, punitive damages, consequential damages, treble damages, costs
and expenses (including all reasonable fees, disbursements and expenses of
counsel, experts and consultants and costs of investigation and feasibility
studies), fines, penalties, sanctions and interest incurred as a result of any
claim or demand by any other Person or in response to any violation of
Environmental Law, whether known or unknown, accrued or contingent, whether
based in contract, tort, implied or express warranty, strict liability, criminal
or civil statute, to the extent based upon, related to, or arising under or
pursuant to any Environmental Law, Environmental Permit, order or agreement with
any Governmental Body or other Person, which relates to any environmental,
health or safety condition, violation of Environmental Law or a Release or
threatened Release of Hazardous Materials.

          "Environmental Law" means any applicable foreign, federal, state or
local statute, regulation, ordinance, rule of common law or other legal
requirement as now or hereafter in effect in any way relating to the protection
of human health and safety, the environment or

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natural resources, including, without limitation, the Comprehensive
Environmental Response, Compensation and Liability Act (42 U.S.C. Section 9601
et seq.), the Hazardous Materials Transportation Act (49 U.S.C. App. Section
1801 et seq.), the Resource Conservation and Recovery Act (42 U.S.C. Section
6901 et seq., the Clean Water Act (33 U.S.C. Section 1251 et seq.), the Clean
Air Act (42 U.S.C. Section 7401 et seq.) the Toxic Substances Control Act (15
U.S.C. Section 2601 et seq.), the Federal Insecticide, Fungicide, and
Rodenticide Act (7 U.S.C. Section 136 et seq.), and the Occupational Safety and
Health Act (29 U.S.C. Section 651 et seq.), as each has been or may be amended
and the regulations promulgated pursuant thereto.

          "Environmental Permit" means any Permit required by Environmental Laws
for the operation of the Business.

          "Escrow Agent" means Wilmington Trust Company in its capacity as
Escrow Agent under the Indemnity Escrow Agreement.

          "Excluded Contracts" means those Contracts of Sellers which are not
set forth in Schedule 1.1(i).

          "Expense Reimbursement" means the reimbursement of Purchaser's
expenses to be paid by Sellers to Purchaser in accordance with the provisions of
Section 7.1 hereof.

          "Extended Units" means the number of tablets, capsules, or milliliters
of liquid, as applicable, of the Marketed Products.

          "FDA" means the United States Food and Drug Administration.

          "Final Order" means any order or judgment which has not been reversed,
vacated, or stayed, and as to which (i) the time to appeal, petition for
certiorari, or move for a new trial, reargument, or rehearing has expired, and
as to which no appeal, petition for certiorari, or other proceedings for a new
trial, reargument, or rehearing shall then be pending, or (ii) if an appeal,
writ of certiorari, new trial, reargument, or rehearing thereof has been sought,
such order or judgment shall have been affirmed by the highest court to which
such order was appealed, or certiorari shall have been denied, or a new trial,
reargument, or rehearing shall have been denied or resulted in no modification
of such order, and the time to take any further appeal, petition for certiorari
or move for a new trial, reargument, or rehearing shall have expired; provided,
however, that the possibility that a motion under Rule 59 or Rule 60 of the
Federal Rules of Civil Procedure, or any analogous rule under the Bankruptcy
Rules, may be filed relating to such order shall not cause such order to not be
a Final Order.

          "GAAP" means generally accepted accounting principles, consistently
applied in the United States in effect at the relevant time.

          "Governmental Body" means any court (including the Bankruptcy Court),
tribunal, arbitrator (public or private), authority, agency, commission,
official or other instrumentality of the United States or any state, county,
city or other political subdivision thereof.

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          "Hazardous Material" means any substance, material or waste that is
regulated, classified, or otherwise characterized under or pursuant to any
Environmental Law as "hazardous," "toxic," "pollutant," "contaminant,"
"radioactive," or words of similar meaning or effect, including, without
limitation, petroleum and its by-products, asbestos, polychlorinated biphenyls,
radon, mold or other fungi, and urea formaldehyde insulation.

          "HSR Act" means the Hart-Scott-Rodino Antitrust Improvements Act of
1976, as amended.

          "IDM" means invention disclosure memorandum.

          "IMS" means IMS Health Inc.

          "IMS National Sales Perspective" means the monthly audit prepared by
IMS and usually available 27 days after the closing of the month. All available
channels of distribution to be included.

          "IMS Product Demand Average Value" means, with respect to each
Marketed Product, the three (3) month rolling average of the latest available
IMS National Sales Perspective data at the time of Closing in Extended Units
(prorated for any partial months) for such Marketed Product times the actual
monthly Net Selling Price for such Marketed Product.

          "Included Books and Records" shall mean all of the books, records,
files, documents, information and correspondences (including Marketing and
Pricing Data) owned by either Seller or any of their Subsidiaries as of the
Closing Date necessary for, or to the extent solely related to, selling,
promoting, manufacturing, advertising, marketing or distributing the Products,
and necessary for, or to the extent related to, all other books, records, files,
documents, information and correspondences that are used in, held for use in or
intended to be used in, or that arise primarily out of, the Business, Pipeline
Products or New Products, including documents relating to Products, services,
Purchased Intellectual Property, personnel files for Transferred Employees and
all customer files and documents (including credit information), supplier lists,
records, literature and correspondences, but excluding the Excluded Books and
Records.

          "Indebtedness" of any Person means, without duplication, (i) the
principal of and premium (if any) in respect of (A) indebtedness of such Person
for money borrowed and (B) indebtedness evidenced by notes, debentures, bonds or
other similar instruments for the payment of which such Person is responsible or
liable; (ii) all obligations of such Person issued or assumed as the deferred
purchase price of property, all conditional sale obligations of such Person and
all obligations of such Person under any title retention agreement (but
excluding trade accounts payable and other accrued liabilities arising in the
Ordinary Course of Business); (iii) all obligations of such Person under leases
required to be capitalized in accordance with GAAP; (iv) all obligations of such
Person for the reimbursement of any obligor on any letter of credit, banker's
acceptance or similar credit transaction; (v) the liquidation value of all
redeemable preferred stock of such Person; (vi) all obligations of the type
referred to in clauses (i) through (v) of any Persons for the payment of which
such Person is responsible or liable, directly or indirectly, as obligor,
guarantor, surety or otherwise, including guarantees of such

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obligations; and (vii) all obligations of the type referred to in clauses (i)
through (vi) of other Persons secured by any Lien on any property or asset of
such Person (whether or not such obligation is assumed by such Person).

          "Indemnity Escrow Agreement" means the Indemnity Escrow Agreement to
be dated as of the Closing Date by and among Sellers, Purchaser and the Escrow
Agent substantially in the form of Exhibit C hereto.

          "Intellectual Property" means: (i) all patents and patent
applications, including continuations, divisionals, continuations-in-part,
re-examinations, extensions, and/or reissues or foreign counterparts of patent
applications and patents issuing thereon (collectively, "Patents"); (ii) all
trademarks, service marks, trade names, service names, brand names, trade dress
rights, logos, and corporate names and general intangibles of a like nature,
together with the goodwill associated with any of the foregoing, and all
applications, registrations, and renewals thereof (collectively, "Trademarks");
(iii) all Internet domain names; (iv) all Copyrights; and (v) all Know How.

          "Intellectual Property Licenses" means (i) any grant to a third Person
of any right to use any of the Purchased Intellectual Property, and (ii) any
grant to Sellers of a right to use a third Person's Intellectual Property rights
which is necessary or useful for the use of any Purchased Intellectual Property
or the development, manufacture, use, sale, offer for sale, distribution,
marketing or promotion of Products.

          "Inventory" means all inventory of finished Marketed Products and
propoxyphene bulk active ingredient owned by Sellers as of the Closing Date,
excluding all other active ingredients, raw materials, or work in progress. For
purposes of "Parent Closing Date Inventory Adjustment Amount" and "Purchaser
Closing Date Inventory Adjustment Amount," "Inventory" means all items of
inventory with an expiration date of no less than six (6) months following the
Closing Date for Schedule II Marketed Products and with an expiration date of no
less than twelve (12) months following the Closing Date for all other Marketed
Products and in quantities no less than the minimum quantities set forth on
Schedule 1.1(b).

          "IRS" means the United States Internal Revenue Service.

          "Know How" means any and all product specifications, product
formulations, compositions, product designs, plans, technology, ideas, concepts,
trade secrets, manufacturing and packaging processes, technical information,
expertise, skill, practice, inventions, procedures, manufacturing formulae,
manufacturing directions, manufacturing specifications, manufacturing validation
data, component specifications, test methods, preclinical, clinical, toxicology
and stability data, validation data of analytical methods and know how, whether
or not patentable.

          "Knowledge of Sellers" means the actual knowledge, after due inquiry,
of the Persons listed on Schedule 1.1(c).

          "Law" means any foreign, federal, state or local law (including common
law), statute, code, ordinance, rule, regulation or other requirement (including
the Bankruptcy Code).

                                       7

<PAGE>

          "Legal Proceeding" means any judicial, administrative or arbitral
actions, suits, proceedings (public or private) or claims or any proceedings by
or before a Governmental Body.

          "Liability" means any debt, loss, damage, adverse claim, liability or
obligation (whether direct or indirect, known or unknown, asserted or
unasserted, absolute or contingent, accrued or unaccrued, liquidated or
unliquidated, or due or to become due, and whether in contract, tort, strict
liability or otherwise), and including all costs and expenses relating thereto.

          "Licensed Assets" means the Azathioprine ANDA and the Licensed
Intellectual Property.

          "Licensed Intellectual Property" means the Azathioprine Know How, the
Azathioprine Copyrights, the ProSorb Know How, the ProSorb Patents, the ProSorb
Trademark, the Darvocet-N XR IDM and the Darvocet-N XR Patents.

          "Lien" means any lien, pledge, mortgage, deed of trust, security
interest, claim, lease, charge, option, right of first refusal, easement, proxy,
voting trust or agreement, transfer restriction under any shareholder or similar
agreement, encumbrance or any other restriction or limitation whatsoever.

          "Lifecycle Products" means Pipeline Products, Derivative Darvocet
Products, and Derivative Lynxorb Products.

          "Lynxorb Licensed Assets" means the ProSorb Patents, the ProSorb
Trademark and the ProSorb Know How.

          "Lynxorb Know How" means all Know How necessary or useful in
connection with the Lynxorb Product other than the ProSorb Know How.

          "Lynxorb Product" means the product identified in Schedule 1.1 (a).

          "Manufacturing Agreement" means the agreement between Purchaser and
Sellers to manufacture those Products identified on Schedule 2.7(1), in form and
substance mutually agreed upon by each of Purchaser and Sellers and containing
the terms set forth on Schedule 2.7(i) and Exhibit E attached hereto.

          "Marketed Products" means those products identified as currently
marketed products on Schedule 1.1 (d).

          "Marketed Products Know How" means all Know How necessary or useful in
connection with the Marketed Products, except for the Azathioprine Product.

          "Marketing Authorizations" means those NDAs and ANDAs set forth in
Schedule 1.1(e).

          "Marketing and Pricing Data" shall mean (i) copies of all market
research, marketing plans, media plans, advertising, promotional and marketing
books and records, customer lists, sales data, price lists, sales training
materials, and all other pricing, advertising

                                       8

<PAGE>

and promotional information owned by and in the possession or control of Sellers
as of the Closing Date and used solely in connection with the Marketed Products,
and (ii) originals of all Marketed Product labels and inserts and all films,
artwork, photography and other graphic materials related thereto, but excluding
any such items in clauses (i) and (ii) to the extent that (a) any Applicable Law
prohibits their transfer or disclosure to Purchaser or (b) any transfer or
disclosure to Purchaser thereof would subject Sellers to any contractual
liability.

          "Material Adverse Effect" means (a) any event, change, condition
(financial or otherwise) or matter that, individually or in the aggregate,
results in or would be reasonably expected to result in a material adverse
effect on the Purchased Assets and the Licensed Assets taken as a whole; (b) any
written indication by the FDA that a factorial design study (being a study in
which the Darvocet-N XR Product is required to be compared against one or more
of its ingredients alone) will be required for FDA approval of the Darvocet-N XR
Product (it being understood that the results of bioequivalence studies or the
clinical trial results for the Darvocet-N XR Product shall not be deemed to be a
Material Adverse Effect); or (c) a material adverse effect on the ability of
Sellers to consummate the transactions contemplated by this Agreement or perform
their obligations under this Agreement or the Seller Documents, excluding any
such effect to the extent resulting from or arising in connection with (i)
general economic or market changes or changes that generally affect businesses
of the same type as the Business, but only if, in each case, the Purchased
Assets or Licensed Assets are not disproportionately affected; (ii) the filing
of the Chapter 11 Case; or (iii) the public announcement of the transactions
contemplated hereunder. Any determination as to whether any event, change,
circumstance or effect has a Material Adverse Effect shall be made only after
taking into account all effective insurance coverages and third-party
indemnifications with respect to such event, change, circumstance or effect.
Purchaser acknowledges that Seller has ceased actively marketing and promoting
the Marketed Products through a sales force or otherwise and that the cessation
of such marketing and promotion shall not, in and of itself, constitute a
Material Adverse Effect.

          "Modification" means, with respect to any item, any modification,
translation, conversion, compilation, upgrade or other derivative version of, or
change or addition to, such item. "Modified" and "Modify" shall have corollary
meanings.

          "NDA" means a new drug application.

          "Net Sales" means with respect to a Lifecycle Product or New Product,
as the case may be, the gross amount invoiced by a Permitted Seller of such
Lifecycle Product or New Product, to third Persons, less

          (a) trade, quantity and/or cash discounts actually allowed;

          (b) discounts, refunds, rebates, chargebacks, retroactive price
adjustments and any other allowances, credits or payments which effectively
reduce the net selling price; and

          (c) actual Lifecycle Product or New Product returns and allowances, as
the case may be;

provided that in no event shall Net Sales equal less than zero. For the
avoidance of doubt, all licensing fees not based on product sales, milestone
payments and other similar payments

                                       9

<PAGE>

derived from any sublicense, assignment or transfer of the rights to sell or
otherwise market a Lifecycle Product or New Product, as the case may be, shall
be deemed to be Net Sales. Net Sales shall be determined from books and records
maintained in accordance with GAAP and shall be deemed to have been made as of
the recorded sale date according to GAAP for such product.

          "Net Selling Price" means, with respect to a Marketed Product, the
gross amount invoiced by a Seller or a Subsidiary of a Seller for such Marketed
Product, to third Persons, less

          (a) trade, quantity and/or cash discounts actually allowed;

          (b) discounts, refunds, rebates, chargebacks, retroactive price
adjustments and any other allowances, credits or payments (other than
commissions) which effectively reduce the net selling price; and

          (c) actual Marketed Product returns and allowances, as the case may
be.

          "New Licensed Intellectual Property" means any Intellectual Property
necessary or useful in connection with a New Product that Purchaser has elected
to acquire under Section 3.3 other than the New Purchased Intellectual Property
associated with that New Product.

          "New Purchased Intellectual Property" means any Intellectual Property
necessary or useful in connection with a New Product that Purchaser has elected
to acquire under Section 3.3 that does not have general applicability to
products other than the New Product.

          "NSAID" means any non-steroidal anti-inflammatory drug.

          "Odyssey Co-Development Agreement" means the co-development agreement
referenced in Section 3.5, in form and substance mutually agreed upon by
Purchaser and Sellers.

          "Odyssey Ingredient" means the ingredient identified in Schedule
1.1(f).

          "Odyssey Know How" means all Know How necessary or useful in
connection with the Odyssey Product.

          "Odyssey Patents" means those Patents set forth in Schedule 1.1(f).

          "Odyssey Product" means the product identified in Schedule 1.1(f).

          "Order" means any order, injunction, judgment, decree, ruling, writ,
assessment or arbitration award.

          "Ordinary Course of Business" means the ordinary and usual course of
normal day-to-day operations of the Business since January 1, 2005 through the
date hereof.

          "Pain Product" means a prescription pharmaceutical product for which
the FDA labeling in the Indication and Usage section of such product's package
insert could reasonably be expected to include the words "relief or "management"
plus the word "pain."

                                       10

<PAGE>

          "Parent Closing Date Inventory Adjustment Amount" means, with respect
to each item of Inventory, the product of (i) Sellers' actual cost of such item
of Inventory and (ii) the difference between the quantities of such item of
Inventory listed in Schedule 1.1(b) and the quantities included in the Final
Closing Date Inventory.

          "Permits" means any approvals, authorizations, consents, licenses,
permits or certificates.

          "Permitted Seller" means Purchaser and its Affiliates and any
assignee, licensee or sublicensee having the right to sell Marketed Products,
Lifecycle Products or New Products.

          "Person" means any individual, corporation, partnership, firm, joint
venture, association, joint-stock company, trust, unincorporated organization,
Governmental Body or other entity.

          "Pipeline Products" means those products identified as pipeline
products on Schedule 1.1(g).

          "PK Study" means a pharmacokinetics study.

          "Post-Signing Shipment Value" means, with respect to each Marketed
Product, the total monthly Extended Units (prorated for any partial month) of
such Marketed Product times the actual monthly Net Selling Price of such
Marketed Product shipped to a customer by or on behalf of either Seller from the
date hereof through and including the Closing Date, as reported by SPS Cord.

          "Product Registration Data" shall mean, to the extent solely related
to a Product and owned by and in the possession and control of Sellers as of the
Closing Date, the following (including electronic copies where no hard copies
exist): (i) all regulatory files relating thereto, other than the Marketing
Authorizations, Purchased DMFs and Purchased INDs, including, but not limited
to, any Permits (to the extent transferable), and minutes of meetings and
telephone conferences with the FDA, validation data, preclinical and clinical
studies and tests related to the applicable Product, and all audit reports of
clinical studies, plus all annual reports and safety reports associated
therewith, drug master files, FDA approvals for export, documents relating to
Phase IV studies and pediatric studies, and all correspondence with the FDA
regarding the marketing status of such applicable Product; and (ii) all records
maintained under current good manufacturing practices or other record keeping or
reporting requirements of the FDA, the DEA, the Occupational Safety and Health
Administration or any other Governmental Body, including, but not limited to,
FDA warning letters, FDA Notices of Adverse Finding Letters, FDA audit reports
(including any comments on such reports), all other correspondence and
communications with regulatory agencies in connection with such Product
(including any advertising and promotion documents and 2253 forms), adverse
event files, complaint files and manufacturing records.

          "Products" means the Marketed Products set forth in Schedule 1.1 (d),
and the Pipeline Products set forth in Schedule 1.1(g).

                                       11

<PAGE>

          "ProSorb Know How" means the Know How necessary or useful in
connection with the Lynxorb Product, which Know How has general applicability
beyond that product.

          "ProSorb Patents" means the Patents set forth in Schedule 1.1(h).

          "ProSorb Trademark" means the common law rights in the United States
to use the phrase "ProSorb" as a trademark and the rights arising under the
United States registration of the trademark for "ProSorb," registration number
2,346,573.

          "Purchased Contracts" means the Contracts set forth in Schedule
1.1(i). Purchaser shall have the right, by written notice delivered to Sellers
at any time during the period from and after the date hereof and until the
Closing Date to delete any Contract from Schedule 1.1 (i) (it being understood
that any such Contract deleted by Purchaser from such schedule may subsequently
be rejected by Sellers in the Chapter 11 Case and, if so rejected, Purchaser
shall reimburse Sellers for any administrative expenses incurred by Sellers
after the commencement of the Chapter 11 Case as a result of the rejection of
such Contract). Purchaser shall also have the right by written notice delivered
to Sellers at any time during the period from and after the date hereof and
until the Closing Date to add any Contract to Schedule 1.1 (i) that was not
disclosed to Purchaser prior to the date hereof. Schedule 1.1(i) also sets forth
the estimated amounts (as of the date hereof) of all amounts which Sellers
expect will be payable pursuant to Section 365(b) of the Bankruptcy Code on
account of the assumption and assignment of any Purchased Contract.

          "Purchased DMFs" means those drug master files set forth in Schedule
1.1(i).

          "Purchased INDs" means those investigational new drug applications set
forth in Schedule 1.1(k).

          "Purchased Intellectual Property" means all right, title, and interest
in and to the following Intellectual Property which is owned (and not licensed)
by Sellers: (i) all the Trademarks set forth on Schedule 1.1(1) (the "Purchased
Trademarks"); (ii) all the Internet domain names set forth on Schedule 1.1(1)
(the "Purchased Domain Names"); (iii) all the Copyrights in all advertising,
marketing, promotional and packaging materials relating to the Products (other
than the Azathioprine Copyrights), exclusive of any portions of advertising,
marketing, promotional and packaging materials describing the business of
Sellers or incorporating the AAI Trademarks and any variations thereof and
related logos or symbols (the "Purchased Copyrights"); (iv) all Patents set
forth in Schedule 1.1(1) (the "Purchased Patents"); (v) the Marketed Product
Know How; (vi) the Darvocet-N XR Know How; (vii) the Darvocet-N Suspension Know
How; and (viii) the Lynxorb Know How.

          "Purchaser Closing Date Inventory Adjustment Amount" means, with
respect to each item of Inventory, the product of (i) Sellers' actual cost of
such item of Inventory as of the Closing Date and (ii) the difference between
the quantities of such item of Inventory listed in Schedule 1.1(b) and the
quantities included in the Final Closing Date Inventory.

          "Purchaser's Indemnity Escrow Amount" means $2,000,000.

                                       12

<PAGE>

          "Purchaser's Indemnity Escrow Fund" means the Purchaser's Indemnity
Escrow Amount together with all interest or income actually earned thereon
pursuant to the Indemnity Escrow Agreement.

          "Release" means any release, spill, emission, leaking, pumping,
injection, deposit, disposal, discharge, dispersal, or leaching into the indoor
or outdoor environment, or into or out of any property.

          "Remedial Action" means all actions to (i) clean up, remove, treat or
in any other way remediate any Hazardous Material; (ii) prevent the Release of
any Hazardous Material so it does not endanger or threaten to endanger public
health or welfare or the indoor or outdoor environment; (iii) perform
pre-remedial studies and investigations or post-remedial monitoring and care; or
(iv) to correct a condition of noncompliance with Environmental Laws.

          "Restructuring Transaction" means (a) a recapitalization transaction
involving, in whole or in part, Sellers and its existing security holders or
creditors, or (b) a transaction or series of transactions, including by way of a
plan of reorganization, in connection with a liquidation or reorganization or
other continuation of Seller's business relating to some or all of the Purchased
Assets.

          "Sale Order" means the order of the Bankruptcy Court in the form
attached hereto as Exhibit H, including such changes thereto requested or
approved by Purchaser in its sole discretion.

          "Sellers' Indemnity Escrow Amount" means $8,000,000.

          "Sellers' Indemnity Escrow Fund" means the Sellers' Indemnity Escrow
Amount together with all interest or income actually earned thereon pursuant to
the Indemnity Escrow Agreement.

          "Services Agreement" means the agreement to provide services with
respect to the Marketed Products, Purchaser Developed Products, Lifecycle
Products, and New Products, in form and substance mutually agreed upon by
Purchaser and Sellers and containing the terms set forth on Schedule 2.7(ii) and
Exhibit G attached hereto.

          "Shipping Adjustment Amount" means the cash value of the difference
between the sum of the Post-Signing Shipment Values for all Marketed Products
minus the sum of the IMS Product Demand Average Values for all Marketed
Products, in the event that the sum of the Post-Signing Shipment Values is
greater than the sum of the IMS Product Demand Average Values.

          "Split Lot" means any lot of Marketed Product that Sellers have sold
some, but not all, of the applicable Marketed Product in such lot prior to the
Closing Date.

          "SPS Cord" means Cardinal Health 105, Inc. (formerly known as Cord
Logistics, Inc.), an Ohio corporation.

                                       13

<PAGE>

          "Subsidiary" means any Person of which a majority of the outstanding
voting securities or other voting equity interests are owned, directly or
indirectly, by such Person.

          "Tax" or "Taxes" means (i) any and all federal, state, local or
foreign taxes, charges, fees, imposts, levies or other assessments, including,
without limitation, all net income, gross receipts, capital, sales, use, ad
valorem, value added, transfer, franchise, profits, inventory, capital stock,
license, withholding, payroll, employment, social security, unemployment,
excise, severance, stamp, occupation, property and estimated taxes, customs
duties, fees, assessments and charges of any kind whatsoever, (ii) all interest,
penalties, fines, additions to tax or additional amounts imposed by any Taxing
Authority in connection with any item described in clause (i), and (iii) any
liability in respect of any items described in clauses (i) and/or (ii) payable
by reason of contract, assumption, transferee liability, operation of law,
Treasury Regulation section 1.1502-6(a) (or any predecessor or successor thereof
or any analogous or similar provision under law) or otherwise.

          "Taxing Authority" means the IRS and any other Governmental Body
responsible for the administration of any Tax.

          "Tax Return" means any return, report or statement required to be
filed with respect to any Tax (including any attachments thereto, and any
amendment thereof) including, but not limited to, any information return, claim
for refund, amended return or declaration of estimated Tax, and including, where
permitted or required, combined, consolidated or unitary returns for any group
of entities that includes the Sellers or any of their Subsidiaries.

          "Territory" means worldwide.

          "WARN" means the Worker Adjustment and Retraining Notification Act of
1988, as amended.

     1.2 Terms Defined Elsewhere in this Agreement. For purposes of this
Agreement, the following terms have meanings set forth in the sections
indicated:

<TABLE>
<CAPTION>
Term                                  Section
----                                  -------
<S>                                   <C>
AAI Packaging                         8.12
Agreement                             Recitals
Adjustment Deadline                   3.1
Allocation Objection Notice           12.3
Allocation Response Period            12.3
Antitrust Division                    8.7(a)
Antirust Laws                         8.7(b)
Asset Acquisition Statement           12.3
Assumed Liabilities                   3.1
Audit Termination Date                3.6(a)
Balance Sheet                         5.5(a)
Balance Sheet Date                    5.5(a)
Bankruptcy Code                       Recitals
Bankruptcy Court                      Recitals
</TABLE>

                                       14

<PAGE>

<TABLE>
<CAPTION>
Term                                  Section
----                                  -------
<S>                                   <C>
Basket                                11.4(a)
Chapter 11 Case                       Recitals
Chargeback Termination Date           8.14(c)
Closing                               4.1
Closing Date                          4.1
Closing Date Inventory Statement      3.7(a)
Commitment Letters                    6.6
Confidential Information              8.9(d)
Confidentiality Agreement             8.9(d)
Cure Amounts                          2.6
Cure Deadline                         3.5(d)
Darvocet-N XR Patents                 2.2(f)(ii)
Development Costs                     8.4
Disclosing Party                      8.9(d)
Domain Name Transfer Agreement        4.2(1)
Excess Cure Amount                    2.6
Exchange Act                          5.5(c)
Excluded Assets                       2.3
Excluded Books and Records            2.3(d)
Excluded Liabilities                  2.5
Expenses                              11.2(a)(vi)
Final Closing Date Inventory          3.7(e)
Financial Statement of the Business   5.5(b)
Financial Statements                  5.5(a)
Five Year Period                      3.3(c)
FTC                                   8.7(a)
Indemnification Claim                 11.3(a)
Lifecycle Product Statement           3.2
LLC                                   Recitals
Losses                                11.2(a)(i)
New Combo Product                     3.3(b)
New Internal Product                  3.3(c)
New P/D Product                       3.3(a)
New Product Statement                 3.3(h)
Net Cash Proceeds                     3.5(b)
Net Sale Proceeds                     3.5(c)
Net Sales Statement                   3.6(a)
Non-Solicitation Period               7.3(a)
Notebooks                             2.1(f)
Parent                                Recitals
Parent Inventory Payment              3.7(e)
Patents                               1.1 (in Intellectual Property definition)
Period of Election                    3.3(a)
Post-Signing Shipments Statement      3.8
Purchased Assets                      2.1
</TABLE>

                                       15

<PAGE>

<TABLE>
<CAPTION>
Term                                  Section
----                                  -------
<S>                                   <C>
Purchase Price                        3.1
Purchase Price Adjustment             3.1
Purchaser                             Recitals
Purchaser Developed Product           3.3(b)
Purchaser Documents                   6.2
Purchaser Indemnified Parties         11.2(a)
Purchaser Inventory Payment           3.7(e)
Rebates Termination Date              8.14(b)
Recalls                               8.16
Receiving Party                       8.9(d)
Rejected Pain Products                2.2(c)(ii)
Restricted Business                   8.9(a)
Restrictive Agreements                8.21
Revised Statements                    12.2
SEC                                   5.5(c)
Securities Act                        8.18
Sellers                               Recitals
Seller Documents                      5.2
Seller Indemnified Parties            11.2(b)
Seller Representatives                7.3(a)
Seven Year Period                     3.3(a)
Survival Period                       11.1
Ten Year Period                       3.3(d)(i)
Trademark Assignment Agreement        4.2(b)
Transferred Employees                 9.1(a)
Transfer Taxes                        12.1
Unresolved Claims                     11.5
WAC                                   8.14(e)
</TABLE>

     1.3 Other Definitional and Interpretive Matters

          (a) Unless otherwise expressly provided, for purposes of this
Agreement, the following rules of interpretation shall apply:

          Calculation of Time Period. When calculating the period of time before
which, within which or following which any act is to be done or step taken
pursuant to this Agreement, the date that is the reference date in calculating
such period shall be excluded. If the last day of such period is a non-Business
Day, the period in question shall end on the next succeeding Business Day.

          Dollars. Any reference in this Agreement to $ means U.S. dollars.

          Exhibits/Schedules. The Exhibits and Schedules to this Agreement are
hereby incorporated by reference and made a part hereof and are an integral part
of this Agreement. All Exhibits and Schedules annexed hereto or referred to
herein are hereby incorporated in and made

                                       16

<PAGE>

a part of this Agreement as if set forth in full herein. Any capitalized terms
used in any Schedule or Exhibit but not otherwise defined therein shall be
defined as set forth in this Agreement.

          Gender and Number. Any reference in this Agreement to gender shall
include all genders, and words imparting the singular number only shall include
the plural and vice versa.

          Headings. The provision of a Table of Contents, the division of this
Agreement into Articles, Sections and other subdivisions and the insertion of
headings are for convenience of reference only and shall not affect or be
utilized in construing or interpreting this Agreement. All references in this
Agreement to any "Section" are to the corresponding Section of this Agreement
unless otherwise specified.

          Herein. The words such as "herein," "hereinafter," "hereof," and
"hereunder" refer to this Agreement as a whole and not merely to a subdivision
in which such words appear unless the context otherwise requires.

          Including. The word "including" or any variation thereof means
"including, without limitation" and shall not be construed to limit any general
statement that it follows to the specific or similar items or matters
immediately following it.

          (b) The parties hereto have participated jointly in the negotiation
and drafting of this Agreement and, in the event an ambiguity or question of
intent or interpretation arises, this Agreement shall be construed as jointly
drafted by the parties hereto and no presumption or burden of proof shall arise
favoring or disfavoring any party by virtue of the authorship of any provision
of this Agreement.

                                   ARTICLE II

             PURCHASE AND SALE OF ASSETS; ASSUMPTION OF LIABILITIES

     2.1 Purchase and Sale of Assets. On the terms and subject to the conditions
set forth in this Agreement, at the Closing Purchaser shall (or shall cause its
designated Affiliate or Affiliates to) purchase, acquire and accept from
Sellers, and Sellers shall (and shall cause its Subsidiaries to) sell, transfer,
assign, convey and deliver to Purchaser (or its designated Affiliate or
Affiliates) all of Sellers' right, title and interest in, to and under the
Purchased Assets, free and clear of all Liens, claims (as defined in Section
101(5) of the Bankruptcy Code) and interests. "Purchased Assets" means each of
the following assets:

          (a) the Purchased DMFs;

          (b) the Purchased INDs;

          (c) the Marketing Authorizations;

          (d) the Inventory;

          (e) the Purchased Intellectual Property;

                                       17

<PAGE>

          (f) subject to the terms of Section 8.22, copies of laboratory
notebooks to the extent relating to the Purchased Intellectual Property and the
Licensed Assets ("Notebooks"), it being understood that such Notebooks are
included in Excluded Assets other than the Purchaser's right to receive copies
thereof;

          (g) all rights of Sellers under the Purchased Contracts;

          (h) the Included Books and Records;

          (i) all rights of Sellers under non-disclosure or confidentiality,
non-compete, or non-solicitation agreements relating to Transferred Employees;

          (j) the Calcitriol ANDA;

          (k) the Product Registration Data;

          (l) all goodwill associated with the Purchased Assets; and

          (m) all amounts recoverable or recovered in connection with Legal
Proceedings relating to the Purchased Assets or Licensed Assets commenced after
the Closing Date, subject to Section 2.2(j).

     2.2 Licenses.

          (a) All the licenses granted in this Section 2.2 are subject to the
terms and conditions set forth herein and, in the case of the licenses granted
from Sellers to Purchaser, the terms and conditions set forth in the Services
Agreement and the Manufacturing Agreement.

          (b) Development Cross-License.

               (i) Purchaser to Sellers:

                    (A) From and after the Closing Date, Purchaser hereby grants
               to Sellers, and Sellers accept, a worldwide, perpetual,
               irrevocable royalty-free license to the Patents and Know How
               contained within the Purchased Intellectual Property and the New
               Purchased Intellectual Property to develop any pharmaceutical
               products other than the Darvocet-N XR Product or the Lynxorb
               Product.

                    (B) The license granted in Section 2.2(b)(i)(A) is exclusive
               outside the field of Pain Products and shall become exclusive for
               all products other than Lifecycle Products at the end of the
               Seven Year Period. It is otherwise nonexclusive.

                    (C) Sellers shall use all reasonable efforts to maintain the
               confidentiality of all confidential Know How licensed under this
               Section 2.2(b) and shall not disclose it to any third party other
               than as reasonably warranted in connection with Sellers' licensed
               development activities or

                                       18

<PAGE>

               sublicenses or assignments as contemplated in Section 2.2(1) and
               in any event pursuant to appropriate terms of confidentiality.

               (ii) Sellers to Purchaser:

                    (A) From and after the Closing Date, Sellers hereby grant to
               Purchaser, and Purchaser accepts, a worldwide irrevocable license
               to the Patents and Know How contained within the Licensed
               Intellectual Property and New Licensed Intellectual Property to
               develop any pharmaceutical products in the field of Pain
               Products. This license shall not include fields to the extent and
               for the time covered by other licenses granted in this Section
               2.2 with the intention of the parties being that after taking all
               such licenses into account, Purchaser has the sum of the license
               rights specified in all the relevant sections but for each
               activity of Purchaser, only the license most specific to that
               activity applies.

                    (B) The license granted in Section 2.2(b)(n)(A) shall expire
               at the end of the Seven Year Period, except (x) as otherwise
               granted in this Section 2.2, for which it shall survive; and (y)
               for products that have reached the stage of development by or for
               Purchaser of a prototype and dissolution profile by the end of
               the Seven Year Period, as to which specific products it will
               survive.

                    (C) Purchaser shall have the right, upon request, to receive
               a copy of any written or electronic embodiments of Know How
               contained within the Licensed Intellectual Property and New
               Licensed Intellectual Property that are necessary or useful for
               the development of Pain Products, provided that Purchaser shall
               agree in writing to maintain the confidentiality of such
               information pursuant to appropriate terms of confidentiality;
               provided, further, to the extent not precluded by agreements
               between Sellers and third parties, Purchaser may disclose
               confidential portions of such Know How to third parties
               developing Pain Products on Purchaser's behalf, under appropriate
               written terms of confidentiality. Purchaser shall reimburse
               Sellers at cost for such materials. All such copies will be
               returned to Sellers at the end of the Seven Year Period.

          (c) Exploitation License Back.

               (i) Outside Field of Pain Products. From and after the Closing
Date, Purchaser hereby grants to Sellers, and Sellers accept, a worldwide,
exclusive, perpetual, royalty-free, transferable license to the Patents and Know
How contained within the Purchased Intellectual Property and New Purchased
Intellectual Property to make, have made, distribute, use, sell, offer to sell,
have sold, market, co-market, import, promote and co-promote products other than
Pain Products and Marketed Products.

                                       19

<PAGE>

               (ii) Rejected Pain Products. From and after the Closing Date,
Purchaser hereby grants to Sellers, and Sellers accept a worldwide, exclusive,
perpetual, royalty-free, transferable license (with a right to sublicense
without consent) to the Patents and Know How contained within the Purchased
Intellectual Property and New Purchased Intellectual Property to make, have
made, distribute, use, sell, offer to sell, have sold, market, co-market,
import, promote and co-promote Pain Product(s) that under the terms of Sections
3.3(a) 3.3(b) or 3.3(c), Sellers developed and Sellers offered to Purchaser, and
that Purchaser declined ("Rejected Pain Products"), thereby entitling Sellers to
market such Rejected Pain Product(s) themselves or through a licensee, in which
case the license shall be exclusive but only as to the specific Rejected Pain
Product(s) offered, provided that in the case of rejected New P/D Products, the
license shall only be effective after the Seven Year Period.

               (iii) Non-Offered Pain Products. Purchaser grants to Sellers an
exclusive license under the Patents and Know How contained within the Purchased
Intellectual Property and New Purchased Intellectual Property of scope
equivalent to that granted under Section 2.2(c)(ii) with respect to each product
that under the terms of Section 3.3, Sellers are entitled to develop and market
without offering to Purchaser once such products have reached the stage of
development of a prototype and dissolution profile upon delivery by Sellers of a
written notice describing in reasonable detail the product that will be the
subject of the exclusive license, provided that in no event will any license
granted pursuant to this Section 2.2(c)(iii) under the Purchased Intellectual
Property or New Purchased Intellectual Property restrict Purchaser's rights to
any Product, any New Product Purchaser has elected to acquire under Section 3.3,
any Derivative Lynxorb Product, any Derivative Darvocet Product, the Odyssey
Product or any product that Purchaser is legally authorized to develop under the
license granted in Section 2.2(b)(ii)(A). The scope of the exclusive license
shall be automatically conformed to apply only to the specific product marketed
once that product has reached final formulation.

               (iv) Sellers shall use all reasonable efforts to maintain the
confidentiality of all confidential Know How licensed under this Section 2.2(c)
and shall not disclose it to any third party other than as reasonably warranted
and pursuant to appropriate terms of confidentiality.

          (d) General License.

               (i) Sellers hereby grant Purchaser a license under the Licensed
Intellectual Property and New Licensed Intellectual Property to make, have made,
distribute, use, sell, offer to sell, have sold, market, co-market, import,
promote and co-promote any Pain Products. Purchaser covenants, however, not to
make, have made, distribute, use, sell, offer to sell, have sold, market,
co-market, import, promote or co-promote any Pain Products using the Licensed
Intellectual Property or New Licensed Intellectual Property other than the
Lynxorb Product (as to the Lynxorb Licensed Assets), Derivative Lynxorb Products
(as to the Lynxorb Licensed Assets), Darvocet-N XR Product (as to the Darvocet-N
XR Know

                                       20

<PAGE>

How, the Darvocet-N XR IDM and the Darvocet-N XR Patents), Derivative Darvocet
Products (as to the Darvocet-N XR Know How, the Darvocet-N XR IDM and the
Darvocet-N XR Patents), Darvocet-N Suspension Product, any New Products that
Purchaser has elected to acquire under Section 3.3 and any products that
Purchaser is legally authorized to develop under the license granted in Section
2.2(b)(ii)(A).

               (ii) Rejected Pain Products. The license granted in Section
2.2(d)(i) shall terminate with respect to Rejected Pain Products upon Sellers'
entitlement to market a Rejected Pain Product, but only with respect to the
particular Rejected Pain Product offered.

               (iii) Non-Offered Pain Products. The license granted in Section
2.2(d)(i) shall terminate with respect to Pain Products that under the terms of
Section 3.3 Sellers are entitled to develop and market without offering to
Purchaser once such products have reached the stage of development of a
prototype and dissolution profile upon delivery by Sellers of a written notice
describing in reasonable detail the product that will be the subject of the
termination, provided that in no event will the termination with respect to the
Purchased Intellectual Property or New Purchased Intellectual Property restrict
Purchaser's rights to any Product, any New Product Purchaser has elected to
acquire under Section 3.3, any Derivative Lynxorb Product, any Derivative
Darvocet Product, the Odyssey Product or any product that Purchaser is legally
authorized to develop under the license granted in Section 2.2(b)(ii)(A). The
scope of the termination shall be automatically conformed to apply only to the
specific product marketed once that product has reached final formulation.

          (e) Lynxorb License.

               (i) Sellers hereby grant to Purchaser, and Purchaser accepts a
worldwide, exclusive, perpetual, transferable license under the Lynxorb Licensed
Assets and New Licensed Intellectual Property necessary or useful for the
Lynxorb Product or Derivative Lynxorb Products in order to develop, make, have
made, distribute, use, sell, offer to sell, have sold, market, co-market,
import, promote and co-promote the Lynxorb Product and Derivative Lynxorb
Products, which license is irrevocable for all assets other than the ProSorb
Trademark, but which as to the ProSorb Trademark may be terminated as set forth
in Section 2.2(e)(ii). For the avoidance of doubt, Sellers retain all rights to
exploit the ProSorb Trademark for products other than with respect to the
Lynxorb Product and Derivative Lynxorb Products and Purchaser is prohibited from
exploiting its trademark rights under this Section 2.2(e)(i) except with respect
to the Lynxorb Product and Derivative Lynxorb Products.

               (ii) All uses by Purchaser, its Affiliates and their respective
sublicensees and assigns of the ProSorb Trademark (whether on Lynxorb Products
or Derivative Lynxorb Products, in marketing materials or otherwise) shall be in
an appropriate manner, without jeopardizing the significance, distinctiveness or
validity of such trademarks; shall use the designation "(R)" with such
trademarks and labeled as a registered trademark of Parent; and shall only be in
such form and manner as approved in writing by Sellers. Purchaser shall only use
the ProSorb Trademark on products of high quality that do not tarnish, dilute or
diminish the current value of such trademarks. All

                                       21

<PAGE>

trademark rights from the use of the ProSorb Trademark by Purchaser, its
Affiliates and their respective sublicensees and assigns will inure to the
benefit of Sellers. Neither Purchaser, its Affiliates nor their respective
sublicensees and assigns shall contest or challenge the validity of, or Sellers'
ownership of, the ProSorb Trademark. All Lynxorb Products and Derivative Lynxorb
Products and related marketing materials featuring the ProSorb Trademark must be
manufactured, labeled, sold, distributed and advertised in accordance with all
Applicable Laws. Once each calendar year upon the written request of Sellers, in
order that Sellers can assure themselves of the maintenance of the
above-described quality standards, Purchaser and its Affiliates will, and shall
cause their respective sublicensees and assigns to: (i) provide to Sellers at
cost (not to exceed $10.00) two (2) then-current production samples of each
Lynxorb Product or Derivative Lynxorb Product featuring the ProSorb Trademark
(with the current packaging) to the extent not manufactured by AAI DS, together
with two (2) copies of all marketing materials, and (ii) permit Sellers to
inspect the manufacturing process for each Lynxorb Product and Derivative
Lynxorb Product not manufactured by AAI DS featuring the ProSorb Trademark upon
five (5) Business Days prior notice, which inspection shall be scheduled during
normal business hours. If Sellers reasonably determine that Purchaser has
breached the provisions of this Section 2.2(e)(ii) with respect to the ProSorb
Trademark and such breach is not materially cured within sixty (60) days after
Purchaser's receipt of written notice thereof, Sellers may terminate the license
granted in Section 2.2(e)(i) above with respect to the ProSorb Trademark subject
to such violation immediately upon written notice to Purchaser.

          (f) Darvocet-N XR License.

               (i) Sellers hereby grant to Purchaser, and Purchaser accepts a
     worldwide, exclusive, perpetual, irrevocable, transferable license under
     the Darvocet-N XR Know How, Darvocet-N XR IDM and New Licensed Intellectual
     Property necessary or useful for Darvocet-N XR Product or Derivative
     Darvocet Products in order to develop, make, have made, distribute, use,
     sell, offer to sell, have sold, market, co-market, import, promote and
     co-promote the Darvocet-N XR Product and Derivative Darvocet Products.

               (ii) Sellers hereby grant to Purchaser, and Purchaser accepts a
     worldwide, exclusive, perpetual, irrevocable, transferable license under
     any patent that solely and exclusively relates to the Darvocet-N XR Product
     (the "Darvocet-N XR Patents") with respect to the full scope of rights
     provided by such patent.

          (g) Azathioprine Product License. Sellers hereby grant to Purchaser,
and Purchaser accepts a worldwide, exclusive, perpetual, irrevocable,
transferable license under the Azathioprine Product Assets in order to develop,
make, have made, distribute, use, sell, offer to sell, have sold, market,
co-market, import, promote and co-promote the Azathioprine Product. For the
avoidance of doubt, no right is granted hereunder to use the Azathioprine
Product Assets in connection with any dosages other than the 50 mg dose of the
Azathioprine Product.

          (h) Patent Prosecution.

                                       22

<PAGE>

               (i) Platform Patents. Sellers shall prepare and file, at Sellers'
     expense, subject to the review and approval of Purchaser, one or more
     patent applications claiming the invention disclosed in the Darvocet-N XR
     IDM or as further developed to the final Darvocet-N XR Product. Once filed,
     prosecution of that patent application shall be under the control and the
     expense of Sellers. Purchaser agrees to coordinate with Sellers in the
     prosecution of those applications to ensure consistency with Sellers' other
     patent filing efforts regarding similar and "platform" inventions. Sellers
     shall give due consideration to Purchaser's input in the prosecution of
     these applications.

               (ii) Lynxorb. Purchaser shall prepare and file, to the extent
     possible, at Purchaser's expense, subject to the review of Sellers, one or
     more patent applications claiming potentially patentable subject matter to
     the extent solely and directly related to the Lynxorb Product.

               (iii) Other Licensed Patents. Sellers shall prepare and file, at
     Sellers' expense, to the extent practicable, subject to the review, but not
     approval, of Purchaser, all other patent applications that are contained
     within the Licensed Intellectual Property with a scope that allows at a
     minimum for protection of the final Darvocet-N XR Product and Lynxorb
     Product. Once filed, prosecution of these applications shall be under the
     control of and at the expense of Sellers. Sellers agree to coordinate with
     Purchaser in the prosecution of those applications to ensure consistency
     with Purchaser's other patent filing efforts and the development of the
     products acquired hereunder. Sellers shall give due consideration to
     Purchaser's input in the prosecution of these applications.

               (iv) Purchaser Prosecution Rights. Sellers hereby appoint
     Purchaser its agent to file patent applications claiming the inventions
     contained within the Licensed Intellectual Property and prosecute such
     applications and any other patent applications contained within the
     Licensed Intellectual Property that solely pertain to Pain Products.
     Purchaser covenants, however, not to exercise its right to so file and
     prosecute while Sellers are making commercially reasonable efforts to file
     and prosecute such inventions.

          (i) Orange Book. Purchaser hereby agrees that if Sellers request that
any Patents contained in the Purchased Intellectual Property or New Purchased
Intellectual Property be listed in the Orange Book and such listing would
protect products of Sellers other than those acquired hereunder, it will consent
to such listing so long as it does not reasonably believe, in good faith, that
such listing would give rise to a claim of patent misuse. Sellers hereby agree
that if Purchaser requests that any Patents contained in the Licensed
Intellectual Property or New Licensed Intellectual Property be listed in the
Orange Book and such listing would protect products acquired hereunder, it will
consent to such listing so long as it does not reasonably believe, in good
faith, that such listing would give rise to a claim of patent misuse.

          (j) Third Party Infringement.

               (i) If either party learns of any actual or threatened
     infringement, misappropriation, dilution, tarnishment, or unauthorized use
     of the Purchased Intellectual Property or Licensed Intellectual Property by
     any third Person, such party shall notify the other party of such
     infringement in writing. Either party shall have the right, but not the

                                       23

<PAGE>

     obligation, to take any action against such third Person to stop the same,
     or otherwise enforce Purchaser's rights in the Purchased Intellectual
     Property and Seller's rights in the Licensed Intellectual Property. If a
     party initiates suit as contemplated in this Section 2.2(j)(i), such party
     shall have the exclusive right to employ counsel of its own selection and
     to direct and control the litigation or any settlement thereof. The party
     that initiates suit shall notify the other party in writing. In the event
     either party initiates suit, (A) the other party shall cooperate in such
     action, (B) the other party shall have the right to retain separate counsel
     in connection with any such action (the costs of such separately-retained
     counsel at that party's expense, provided, that if the other party is a
     necessary party to such action, the costs of such separately retained
     counsel shall be at the expense of the party bringing the action), and (C)
     the party bringing the action shall reimburse the other party for all
     reasonable costs, attorneys' fees and other expenses incurred by the other
     party in connection with such action, including appropriate reimbursement
     for time of that party's personnel involved in discovery, trial and other
     related matters, except as provided in Section 2.2(j)(i)(B). Nothing herein
     shall be construed to prevent Sellers and Purchaser from taking action
     jointly in any infringement suit or other action with respect to the
     Purchased Intellectual Property.

               (ii) Each party shall be entitled to any recovery of damages
     (including payments received in any settlement) resulting from a lawsuit
     brought solely in its own name and, in the event both Sellers and Purchaser
     are joint parties to any lawsuit, Sellers and Purchaser shall share in any
     recovery, after reimbursement of each party's expenses in connection with
     the action, including appropriate reimbursement for time of that party's
     personnel involved in discovery, trial and other related matters, in
     proportion to the expenses it incurred. Neither party may settle with an
     infringer in a manner which could reasonably be considered to negatively
     impact any rights of the other without the other's prior written approval,
     which approval shall not be unreasonably withheld or delayed.

          (k) Sellers agree that they will not, during or after the term of this
Agreement, in any way challenge the validity of the Purchased Intellectual
Property or Purchaser's ownership thereof. Purchaser agrees that if Purchaser
challenges the validity of the Licensed Intellectual Property, Purchaser will
pay Sellers' expenses in connection therewith.

          (l) Any license granted pursuant to this Section 2.2 shall be freely
transferable and sub licensable, and may be assumed and/or assigned in whole or
in part without the consent of any Party, so long as the transfer, sublicense,
assumption and/or assignment is subject to the obligation and restrictions
contained in this Agreement.

          (m) Purchaser acknowledges and agrees that a breach of Sections
2.2(d)(i) (second sentence) or 3.4(b) (last paragraph) would cause irreparable
damage to Sellers not compensable by monetary damages and that Sellers will not
have an adequate remedy at law. Therefore, Purchaser's obligations under Section
2.2(d)(i) (second sentence) or 3.4(b) (last paragraph) shall be enforceable by,
and Sellers shall be entitled to seek, temporary, preliminary and/or permanent
equitable or injunctive relief (including a decree of specific performance) from
any court of competent jurisdiction, without the necessity of posting bond.
Sellers' remedies

                                       24

<PAGE>

under this Section 2.2(m) shall, however, be cumulative and not exclusive and
shall be in addition to any other remedies which any party may have under this
Agreement or otherwise.

     2.3 Excluded Assets. Nothing herein contained shall be deemed to transfer,
assign or convey the Excluded Assets to Purchaser, and Sellers shall retain all
right, title and interest to, in and under the Excluded Assets. "Excluded
Assets" means each of the following assets:

          (a) the Excluded Contracts;

          (b) cash, cash equivalents, all prepayments (including all prepayments
made to third party manufacturers, suppliers and contractors), deferred assets,
refunds, credits or overpayments or other receivables for Taxes;

          (c) all accounts receivable of Sellers;

          (d) all books and records to the extent related to or constituting
human resources and any other employee-related files and records for employees
that are not Transferred Employees or any other books and records Sellers are
required by law to retain, (ii) original (but not copies of) financial and
accounting records; (iii) any tax files, returns, documents, instruments,
papers, books and records not related to the Purchased Assets or Assumed
Liabilities; (iv) original (but not copies of, to the extent relating to the
Purchased Intellectual Property and the Licensed Assets) laboratory notebooks
and (v) Excluded Assets or Excluded Liabilities (collectively, the "Excluded
Books and Records");

          (e) the AAI Trademarks;

          (f) the AAI IP;

          (g) all rights of Sellers under or pursuant to all warranties,
representations and guarantees made by suppliers, manufacturers and contractors
to the extent relating to Products sold by, or services provided to, Sellers or
to the extent affecting any Purchased Assets in respect of matters occurring
prior to the Closing Date;

          (h) any refund or credit of (i) Taxes that relate to the Purchased
Assets or the Assumed Liabilities attributable to any period or portion thereof
ending prior to the Closing Date, including any Taxes allocated to Sellers
pursuant to Section 12.2 and (ii) Taxes of Sellers that are not Assumed
Liabilities;

          (i) all deposits (including customer deposits and security deposits
for rent, electricity, telephone or otherwise) and prepaid charges and expenses
of Sellers and its Subsidiaries;

          (j) all amounts recoverable or recovered by Sellers or their
Affiliates in connection with any Legal Proceedings commenced prior to the
Closing Date, or after the Closing Date to the extent not related to the
Purchased Assets or the Licensed Assets subject to Section 2.2(j).

          (k) all manufacturing and laboratory facilities;

                                       25

<PAGE>

          (l) all computers, software and office equipment, personal property,
furniture, fixtures and equipment;

          (m) all real estate and leasehold interests of Sellers; and

          (n) all businesses of Sellers and their Affiliates other than the
Business.

     2.4 Assumption of Liabilities. On the terms and subject to the conditions
set forth in this Agreement, at the Closing Purchaser shall (or shall cause its
designated Affiliate or Affiliates to) assume, effective as of the Closing, only
the following liabilities of Sellers (collectively, the "Assumed Liabilities"):

          (a) all Liabilities of Sellers under the Purchased Contracts that
arise out of or relate to the period on and after the Closing Date;

          (b) all Liabilities for (i) Purchaser's portion of the Transfer Taxes
pursuant to Section 12.1 and (ii) Taxes that relate to the Purchased Assets or
the Assumed Liabilities for taxable periods (or portions thereof) beginning on
or after the Closing Date, including any Taxes allocated to Purchaser pursuant
to Section 12.2; and

          (c) all Liabilities relating to amounts required to be paid by
Purchaser hereunder.

     2.5 Excluded Liabilities. Notwithstanding anything in this Agreement to the
contrary, Purchaser shall not assume, and shall be deemed not to have assumed,
any Liabilities relating to the Business of Sellers or any Affiliate of Sellers
except as expressly provided in Section 2.4 hereof or elsewhere in this
Agreement, and Sellers and their Affiliates shall be solely and exclusively
liable with respect to all such Liabilities, other than the Assumed Liabilities
(collectively, the "Excluded Liabilities"), including without limitation, those
Liabilities set forth below:

          (a) all Liabilities in respect of any and all Products sold and/or
services performed by Sellers before the Closing Date, including product
liability claims;

          (b) all Environmental Costs and Liabilities, to the extent arising out
of or otherwise related to (i) the ownership or operation by Sellers of the
Business on or prior to the Closing Date, (ii) the manufacture by Sellers' or
their Subsidiaries at any time of the Products set forth in Exhibit E and (iii)
the Excluded Assets or any other real property presently or formerly owned,
operated, leased or otherwise used by Seller;

          (c) except to the extent specifically provided in Article IX, all
Liabilities arising out of, relating to or with respect to (i) the employment or
performance of services, or termination of employment or services by Sellers or
any of its Affiliates of any individual before the Closing Date, (ii) workers'
compensation claims against Sellers or any of their Subsidiaries that relate to
the period before the Closing Date, irrespective of whether such claims are made
prior to or after the Closing or (iii) any employee benefit plan of Sellers or
their Affiliates;

                                       26

<PAGE>

          (d) all Liabilities arising out of, under or in connection with
Contracts that are not Purchased Contracts and, with respect to Purchased
Contracts, Liabilities in respect of a breach by or default of Sellers accruing
under such Contracts with respect to any period prior to Closing and all Cure
Amounts;

          (e) all Liabilities arising out of, under or in connection with any
Indebtedness of Sellers or any of their Subsidiaries;

          (f) all Liabilities for (i) Sellers' portion of the Transfer Taxes
pursuant to Section 12.1, (ii) Taxes of Sellers that are not Assumed
Liabilities, (iii) Taxes that relate to the Purchased Assets or the Assumed
Liabilities for taxable periods (or portions thereof) ending before the Closing
Date, including any Taxes allocated to Sellers pursuant to Section 12.2, and
(iv) payments under any Tax allocation, sharing or similar agreement (whether
oral or written) with respect to which Sellers or any Affiliates are liable;

          (g) all Liabilities in respect of any pending or threatened Legal
Proceeding, or any claim arising out of, relating to or otherwise in respect of
(i) the operation of the Business to the extent such Legal Proceeding or claim
relates to such operation prior to the Closing Date, or (ii) any Excluded Asset;
and

          (h) all Liabilities relating to amounts required to be paid by Sellers
hereunder.

     2.6 Cure Amounts. At Closing and pursuant to Section 365 of the Bankruptcy
Code, Sellers shall assume and assign to Purchaser the Purchased Contracts. The
cure amounts, as determined by the Bankruptcy Court, if any (the "Cure
Amounts"), necessary to cure all defaults, if any, and to pay all actual or
pecuniary losses that have resulted from such defaults under the Purchased
Contracts, shall be paid by Sellers, on or before Closing, and not by Purchaser
and Purchaser shall have no liability therefor. Notwithstanding the foregoing,
in the event the actual Cure Amounts for all Purchased Contracts required to be
paid by Sellers on the Closing Date in accordance with this Section 2.6 exceed
the aggregate of the estimated Cure Amounts set forth on Schedule 1.1(i) for
such Purchased Contracts (such excess, the "Excess Cure Amount") by $6,000,000
or more, then Purchaser may, by written notice to Sellers, elect to (i) pay the
amount by which the Excess Cure Amount exceeds $6,000,000 and/or (ii) cause
Sellers to reject any Purchased Contract or (iii) to the extent the failure to
assume the Purchased Contract would result in a Material Adverse Effect,
terminate this Agreement in accordance with Section 4.4(f). If Purchaser elects
to proceed pursuant to clause (i) and/or (ii) above, then Sellers shall pay, in
addition to the aggregate Cure Amounts specified in Schedule 1.1 (i), the first
$6,000,000 of the Excess Cure Amount.

     2.7 Services Agreement, Manufacturing Agreement and Odyssey Co-Development
Agreement. At the Closing, Purchaser and Sellers shall enter into and deliver to
each other the (i) Services Agreement, (ii) Manufacturing Agreement and (iii)
Odyssey Co-Development Agreement.

     2.8 Further Conveyances and Assumptions. From time to time following the
Closing, Sellers and Purchaser shall, and shall cause their respective
Affiliates to, execute, acknowledge and deliver all such further conveyances,
notices, assumptions, releases and acquaintances and

                                       27

<PAGE>

such other instruments, and shall take such further actions, as may be necessary
or appropriate to assure fully to Purchaser and its respective successors or
assigns, all of the properties, rights, titles, interests, estates, remedies,
powers and privileges intended to be conveyed to Purchaser under this Agreement
and the Seller Documents and to assure fully to Sellers and their Affiliates and
their successors and assigns, the assumption of the liabilities and obligations
intended to be assumed by Purchaser under this Agreement and the Seller
Documents, and to otherwise make effective the transactions contemplated hereby
and thereby.

     2.9 Bulk Sales Law. Purchaser hereby waives compliance by Sellers with the
requirements and provisions of any "bulk-transfer" Laws of any jurisdiction that
may otherwise be applicable with respect to the sale of any or all of the
Purchased Assets to Purchaser. Pursuant to Section 363(f) of the Bankruptcy
Code, the transfer of the Purchased Assets shall be free and clear of any
security interests in the Purchased Assets, including any Liens or claims
arising out of the bulk transfer laws, and the parties shall take such steps as
may be necessary or appropriate to so provide in the Sale Order.

                                   ARTICLE III

                                  CONSIDERATION

     3.1 Consideration. The aggregate consideration for the Purchased Assets
shall be (i) the payment by Purchaser to Seller, in the manner provided in
Section 3.9 hereof, of $170,000,000, less the Development Costs, if any (the
"Purchase Price"), provided that if the Closing Date does not occur within the
ninetieth (90th) day following the commencement of the Chapter 11 Case (the
"Adjustment Deadline"), the Purchase Price shall be reduced by $1,500,000 on
each weekly anniversary of the Adjustment Deadline prior to the Closing Date
(the "Purchase Price Adjustment"), provided that the Purchase Price Adjustment
shall not be applicable to any week (or portion thereof) after the Adjustment
Deadline in which (A) there shall be an uncured breach by Purchaser of covenant
or agreement contained in this Agreement which would result in a failure of a
condition set forth in Section 10.2 or 10.3 and all other conditions set forth
in Article X (other than conditions that by their nature are to be satisfied at
the Closing) to have been satisfied or (B) the waiting period under the HSR Act
shall not have expired or early termination shall not have been granted;
provided, further, that in no event, shall the Purchase Price Adjustment exceed
$6,000,000 in the aggregate, (ii) the assumption by Purchaser of the Assumed
Liabilities, and (iii) the payment by Purchaser to Sellers of royalty payments
pursuant to Section 3.2. Commencing on the one hundred twentieth (120th) day
following the commencement of the Chapter 11 Case and provided that the Closing
Date has not yet occurred, Purchaser shall have the right to terminate this
Agreement pursuant to Section 4.4; provided, however, that in the event
Purchaser terminates this Agreement pursuant to Section 4.4, Purchaser shall be
paid the Expense Reimbursement on the first (1st) Business Day after such
termination and Purchaser shall remain entitled to receive the Break-Up Fee in
accordance with Section 7.1 upon the satisfaction of the conditions set forth
therein.

     3.2 Royalties on Lifecycle Products. From the Closing Date through December
31, 2011, Purchaser shall pay to Parent royalties on the aggregate Net Sales of
the Lifecycle Products as follows:

                                       28

<PAGE>

          (a) 0% of Net Sales under $25,000,000 per calendar quarter,

          (b) 5% of Net Sales between $25,000,000 and $50,000,000 per calendar
quarter and

          (c) 10% of Net Sales over $50,000,000 per calendar quarter.

Within ten (10) Business Days after the end of each calendar quarter, Purchaser
shall provide to Parent a written statement (each, a "Lifecvcle Products
Statement"), which shall set forth the aggregate Net Sales of the Lifecycle
Products for such quarter and the calculation of the corresponding royalty
payment. Purchaser shall pay to Parent such royalty payment reflected in such
Lifecycle Products Statement within twenty (20) Business Days after the end of
each calendar quarter.

     3.3 Products Option.

          (a) If at any time between the Closing Date and the seventh (7th)
anniversary of the Closing Date (the "Seven Year Period") Sellers or any of
their Subsidiaries develop to the stage of creation of a prototype and
dissolution profile any new Pain Product (a "New Product") that contains
propoxyphene and/or diclofenac (a "New P/D Product"), then Sellers shall, or
shall cause their Subsidiaries to, offer in writing to Purchaser prior to any
other Person the option for a sixty (60) day period (as such time period may be
extended as provided for in Section 3.3(e), the "Period of Election") to acquire
any such New P/D Product. Purchaser shall accept or reject such offer by Sellers
during the Period of Election. If Purchaser notifies Sellers in writing within
the Period of Election that Purchaser declines to exercise such option to
acquire any such New P/D Product, then Sellers shall not sell, license,
transfer, assign, convey or deliver such New P/D Product to any third party for
the remainder of the Seven Year Period; provided, however, that Purchaser
acknowledges that Sellers may continue to develop (but not commercialize) such
New P/D Product during the Seven Year Period.

          (b) If during the Seven Year Period Sellers or any of their
Subsidiaries develop to the stage of creation of a prototype and dissolution
profile any New Product that (i) does not contain propoxyphene and/or
diclofenac, and (ii) is an opioid/APAP combination or an opioid/NSAID
combination (a "New Combo Product"), then Sellers shall, or shall cause their
Subsidiaries to, offer in writing to Purchaser prior to any other Person the
option for a Period of Election to acquire any such New Combo Product. Purchaser
shall accept or reject such offer by Sellers during the Period of Election. If
Purchaser notifies Sellers in writing within this Period of Election that
Purchaser declines to exercise such option to acquire any such New Combo
Product, then Purchaser shall have no further rights with respect to the New
Combo Product, and Sellers shall have no further obligation to notify Purchaser
with respect to such New Combo Product and may continue to develop, make, have
made, distribute, use, sell, offer to sell, have sold, market, co-market,
import, promote and co-promote such New Combo Product or sublicense such New
Combo Product to a third party.

          (c) If at any time between the Closing Date and the fifth (5th)
anniversary of the Closing Date (the "Five Year Period") Sellers or any of their
Subsidiaries develop to the stage of creation of a prototype and dissolution
profile any New Product for their own internal

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<PAGE>

business purpose and not for any third party, and such New Product (i) does not
contain propoxyphene and/or diclofenac and (ii) is not an opioid/APAP
combination or an opioid/NSAID combination (a "New Internal Product"), then
Sellers shall, or shall cause their Subsidiaries to, offer in writing to
Purchaser prior to any other Person the option for a Period of Election to
acquire any such New Internal Product. Purchaser shall respond to such offer by
Sellers during the Period of Election. If Purchaser notifies Sellers that
Purchaser declines to exercise such option to acquire any such New Internal
Product, then Purchaser shall have no further rights with respect to the New
Internal Product, and Sellers shall have no further obligation to notify
Purchaser with respect to such New Internal Product and may continue to develop,
make, have made, distribute, use, sell, offer to sell, have sold, market,
co-market, import, promote and co-promote such New Internal Product or
sublicense such New Internal Product to a third party.

          (d) If Purchaser notifies Sellers in writing that it elects to acquire
any New Product, within the applicable Period of Election, pursuant to Sections
3.3(a), 3.3(b) or 3.3(c), then:

               (i) Sellers will develop such New Product and, during the period
     of time between the commercial launch of such New Product and the tenth
     (10th) anniversary of such commercial launch (the "Ten Year Period"),
     Purchaser shall pay to Sellers or their Subsidiaries, as the case may be,
     the amounts specified in the Services Agreement in connection with the
     development of such New Product and royalties on the aggregate Net Sales of
     such New Product as follows:

               (x) 7.5% of Net Sales up to and including $25,000,000 per
     calendar quarter, and

               (y) 10% of the portion of Net Sales, if any, over $25,000,000 per
     calendar quarter;

     or

               (ii) Sellers shall notify Purchaser within twenty (20) Business
     Days after their receipt of Purchaser's notice if Sellers are unable or
     unwilling to continue development and production of any such New Product,
     and Sellers shall promptly grant to Purchaser a license to utilize any and
     all intellectual property of Sellers necessary or useful to any such New
     Product to enable Purchaser to either develop such New Product internally
     or utilize a third party to develop such New Product, and during the Ten
     Year Period Purchaser shall pay to Sellers or their Subsidiary, as the case
     may be, royalties on the aggregate Net Sales of such New Product as
     follows:

               (x) 3.75% of Net Sales up to and including $25,000,000 per
     calendar quarter, and

               (y) 5% of the portion of Net Sales, if any, over $25,000,000 per
     calendar quarter;

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<PAGE>

provided that for each Derivative Darvocet Product and each Derivative Lynxorb
Product that Sellers develop and license to Purchaser in accordance with the
terms of this Section 3.3, Purchaser shall pay to Sellers or their Subsidiaries,
as the case may be, royalties pursuant to Section 3.2 prior to December 31, 2011
and royalties pursuant to Section 3.3(d)(i) from the period January 1, 2012
through the end of the Ten Year Period for that product. For each Derivative
Darvocet Product and each Derivative Lynxorb Product that Purchaser develops and
offer to Sellers and that Sellers decline in accordance with the terms of this
Section 3.3, or that Purchaser otherwise develops on its own, Purchaser shall
pay to Sellers or their Subsidiaries, as the case may be, royalties pursuant to
Section 3.2 prior to December 31, 2011 and royalties pursuant to Section
3.3(d)(ii) from the period January 1, 2012 through the end of the Ten Year
Period for that product.

          (e) Notwithstanding the foregoing, with regard to the Period of
Election for an option of Purchaser to acquire a New Product pursuant to Section
3.3(a), Section 3.3(b) or Section 3.3(c), no Period of Election shall expire
less than six (6) months after the expiration of the Period of Election for the
immediately preceding New Product (if any) in the event that Purchaser has
exercised its option to acquire such immediately preceding New Product;
provided, however, that in the event that Purchaser has declined such
immediately preceding New Product, the Period of Election for the then-current
New Product shall expire sixty (60) days after the later of the date that
Purchaser declined such immediately preceding New Product and the date of
submission of the then-current New Product.

          (f) If Sellers or any of their Subsidiaries are contracted to develop
any New Product by and for any unaffiliated third party and not for Sellers' own
internal business purpose, and such New Product (i) does not contain
propoxyphene and/or diclofenac and (ii) is not an opioid/APAP combination or an
opioid/NSAED combination, then Purchaser shall have no rights with respect to
the New Product and Sellers shall have no obligation to notify Purchaser with
respect to such New Product and may develop, make, have made, distribute, use,
sell, offer to sell, have sold, market, co-market, import, promote and
co-promote such New Product or sublicense such New Product to a third party.

          (g) To the extent Purchaser exercises an option under this Section
3.3, if Purchaser notifies Sellers in writing that (y) it elects to develop any
such New Product internally or to utilize a third party to develop such New
Product and (z) it has determined that Sellers are or reasonably could be
impaired in their ability to perform in accordance with Section 3.3 in a timely
manner with respect to any such New Product, Sellers shall promptly grant to
Purchaser a license to utilize any and all intellectual property of Sellers
applicable to any such New Product to enable Purchaser to either develop such
product internally or utilize a third party to develop such product, and during
the Ten Year Period Purchaser shall pay to Sellers or their Subsidiaries, as the
case may be, royalties on the aggregate Net Sales of such New Product as
follows:

               (i) 3.75% of Net Sales up to and including $25,000,000 per
     calendar quarter, and

               (ii) 5% of the portion of Net Sales, if any, over $25,000,000 per
     calendar quarter.

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<PAGE>

          (h) Within ten (10) Business Days after the end of each calendar
quarter, Purchaser shall provide to Parent a written statement (each, a "New
Product Statement"), which shall set forth the aggregate Net Sales of each such
New Product for such calendar quarter and the calculation of the corresponding
royalty payment. Purchaser shall pay to Parent such royalty payment reflected in
such New Product Statement within twenty (20) Business Days after the end of
each calendar quarter.

          (i) With respect to each New Product that Purchaser elects to acquire,
all royalty payments by Purchaser with respect to such New Product pursuant to
this Section 3.3 shall be reduced by 50% upon the commercial launch of a generic
version of such New Product.

          (j) Upon submission of a notice that Purchaser elects to acquire a New
Product, Sellers shall immediately assign to Purchaser all New Purchased
Intellectual Property associated with the New Product.

          (k) In the event that Purchaser elects to acquire a New Product
pursuant to Section 3.3(a), Section 3.3(b) or Section 3.3(c), Purchaser agrees
to use commercially reasonable efforts to develop or have developed, as
applicable, market such New Product; provided, however, that Purchaser shall
have the right to terminate its license to such New Product provided that
Purchaser assigns back the New Purchased Intellectual Property. If Purchaser
terminates its license to such New Product, then Purchaser shall have no further
rights or obligations with respect to the New Product (including, but not
limited to, the obligation to market such New Product), and Sellers may make,
have made, distribute, use, sell, offer to sell, have sold, market, co-market,
import, promote and co-promote such New Product or sublicense such New Product
to a third party (subject to the restrictions regarding New P/D Products during
the Seven Year Period).

          (l) Sellers and Purchaser shall negotiate in good faith the focus of
Sellers' development efforts regarding the New Products that may be submitted
under this Section 3.3 for Purchaser's option, which negotiation is anticipated
to include the planned identity and order of the first several New Products.

          (m) Notwithstanding anything herein to the contrary, any Pain Product
that has been developed to the state of creation of a prototype and dissolution
profile (i) prior to the date hereof, (ii) during the period of time between the
date hereof and the Closing Date, or (iii) after the Closing Date, which is
owned by Sellers or their Subsidiaries and has not been licensed to a third
party prior to the date hereof, shall be considered a New Product which Sellers
shall, or shall cause their Subsidiaries to, offer in writing to Purchaser prior
to any other Person the option for a Period of Election to acquire any such New
Product pursuant to Section 3.3(a), Section 3.3(b) or Section 3.3(c), provided
that such new Pain Product contains or does not contain, as applicable, the
chemical ingredients or compounds required by such sections.

          (n) Notwithstanding anything herein to the contrary, including this
Section 3.3 and Section 8.9, this Agreement shall not prevent Sellers or their
Affiliates from providing any routine services to third parties, where Sellers
or their Affiliates are merely implementing such third parties' instructions and
Sellers or their Affiliates are not engaged in providing formulating services to
such parties or otherwise performing inventive work (including conceiving
inventions

                                       32

<PAGE>

for the third party or reducing the third party's inventions to practice).
Illustrative examples of such non-precluded routine services include (i)
chemical structure analysis and elucidation of compounds or chemicals
independently provided by third parties (without formulation by Sellers or their
Affiliates) (ii) clinical supply manufacturing on a contract basis of compounds
or chemicals independently provided by third parties; (iii) clinical studies;
(iv) validation services with respect to processes and methods; (v) regulatory
services; (vi) method development; and (vii) stability testing.

          (o) For the avoidance of doubt, the terms of Sellers' right to develop
New Products as set forth herein shall be subject to the Services Agreement.

     3.4 Option on Purchaser Developed Products. If at any time during the Seven
Year Period Purchaser wants to internally develop, or wants to utilize a third
party to develop, any Pain Product containing (i) propoxyphene and/or diclofenac
or (ii) an opioid/APAP combination or an opioid/NSAID combination (a "Purchaser
Developed Product"), then Purchaser shall offer in writing to Sellers prior to
any other Person the option for a Period of Election to develop any such
Purchaser Developed Product. Sellers shall respond to such offer by Purchaser
during the Period of Election. If Sellers notify Purchaser that Sellers decline
to exercise such option to develop any such Purchaser Developed Product, then
Sellers shall have no further rights with respect to the Purchaser Developed
Product, and Purchaser shall have no further obligation to notify Sellers with
respect to such Purchaser Developed Product and may develop, or may utilize a
third party to develop, such Purchaser Developed Product. If Seller notifies
Purchaser in writing that it elects to develop any Purchaser Developed Product
within such Period of Election, then:

          (a) Sellers will develop such Purchaser Developed Product and, during
the Ten Year Period, Purchaser shall pay to Sellers or their Subsidiaries, as
the case may be, the amounts specified in the Services Agreement in connection
with the development of such New Product and royalties on the aggregate Net
Sales of such Purchaser Developed Product as follows:

               (i) 7.5% of Net Sales up to and including $25,000,000 per
     calendar quarter, and

               (ii) 10% of the portion of Net Sales, if any, over $25,000,000
     per calendar quarter;

          or

          (b) Sellers shall notify Purchaser within sixty (60) Business Days
after their receipt of Purchaser's notice if Sellers are unable or unwilling to
develop and produce any such Purchaser Developed Product; provided, however,
that Sellers shall have no right to any royalty payments with respect to such
Purchaser Developed Product pursuant to this Section 3.4(b).

          Notwithstanding the foregoing, with regard to the Period of Election
for an option of Sellers to develop a Purchaser Developed Product pursuant to
this Section 3.4, no Period of Election shall expire less than six (6) months
after the expiration of the Period of Election for the immediately preceding
Purchaser Developed Product (if any) in the event that Sellers have

                                       33

<PAGE>

exercised their option to develop such immediately preceding Purchaser Developed
Product; provided, however, that in the event that Sellers have failed to elect
to develop such immediately preceding Purchaser Developed Product, the Period of
Election for the then-current Purchaser Developed Product shall expire sixty
(60) days after the end of the Period of Election in which Sellers failed to
make such election and the date of submission of the then-current Purchaser
Developed Product.

          Purchaser covenants not to develop any pharmaceutical products using
the Patents and Know How contained within the Licensed Assets and Purchased
Assets during the Seven Year Period except with respect to Lifecycle Products
that Purchaser requested Sellers to develop and Sellers were unable or unwilling
to develop, in which case Purchaser may develop such Lifecycle Products itself
or retain a third party to do the same using, in the case of Derivative Darvocet
Products, the Darvocet-N Know How and the Darvocet-N XRIDM and, in the case of
Derivative Lynxorb Products, the ProSorb Patents and the ProSorb Know How.

     3.5 Odyssey.

          (a) On the Closing Date, Purchaser and Sellers shall enter into the
Odyssey Co-Development Agreement for the development and commercialization of
the Odyssey Product. Pursuant to the Odyssey Co-Development Agreement, Sellers
shall grant to Purchaser an exclusive license to the Odyssey Patents and Odyssey
Know How for all pharmaceutical products containing the Odyssey Ingredient as
the sole active ingredient. The Odyssey Co-Development Agreement shall further
provide that Purchaser shall pay for all costs and expenses relating to the
development and commercialization of the Odyssey Product, including costs
arising from the defense and prosecution of the Odyssey Patent application filed
on May 26, 2004 and Odyssey Know How, in each case solely as it relates to
products containing the Odyssey Ingredient.

          (b) Each party shall retain fifty percent (50%) of any cash proceeds
from the development and commercial exploitation of the Odyssey Product (net of
Purchaser's and Sellers' aggregate costs and expenses incurred in connection
with the development and commercial exploitation of the Odyssey Product) (the
"Net Cash Proceeds").

          (c) If Purchaser and Sellers mutually agree to sell the rights to the
Odyssey Product, then each party shall retain fifty percent (50%) of the sale
proceeds (net of Purchaser's and Sellers' aggregate costs and expenses incurred
in connection with the development and commercial exploitation of the Odyssey
Product) (the "Net Sale Proceeds"). To the extent there is any deferred
consideration in such sale, including, but not limited to, milestone payments
and royalties, each party shall retain fifty percent (50%) of any such deferred
compensation.

          (d) Notwithstanding the foregoing, in the event that Purchaser has not
enrolled at least one (1) subject in a PK Study on or prior to the later of six
(6) months (i) from the Closing Date, or (ii) after the date upon which delivery
of the Odyssey Product formulation and clinical supply thereof is made by
Sellers to Purchaser, then thereafter Purchaser shall only retain twenty-five
percent (25%), rather than fifty percent (50%), of any of the Net Sale Proceeds,
deferred compensation and Net Cash Proceeds referred to in Section 3.5(b) and
Section 3.5(c); provided, however, that in the event that Purchaser has enrolled
at least one (1)

                                       34

<PAGE>

subject in a PK Study on or prior to the later of twelve (12) months (x) from
the Closing Date or (y) after the date upon which delivery of the Odyssey
Product formulation and clinical supply thereof is made (the "Cure Deadline"),
Purchaser shall regain its right to receive fifty percent (50%) by Sellers to
Purchaser of any of the Net Sale Proceeds, deferred compensation and Net Cash
Proceeds referred to in Section 3.5(b) and Section 3.5(c); provided, further,
however, if Purchaser fails to enroll at least one (1) subject in a PK Study on
or prior to the Cure Deadline, then Purchaser's rights to the Odyssey Patents
and Odyssey Know How shall revert to Parent, provided that (notwithstanding such
reversion) Purchaser shall retain the right to receive twenty-five percent
(25%), of any of the Net Sale Proceeds, deferred compensation and Net Cash
Proceeds referred to in Section 3.5(b) and Section 3.5(c) and Purchaser shall
thereafter pay for all costs and expenses relating to the development and
commercialization of the Odyssey Product.

          (e) During any period Purchaser retains the rights to the Odyssey
Product in accordance with the foregoing, Purchaser shall pursue the development
and commercialization, including any litigation, relating to the Odyssey Product
and Purchaser shall bear all costs and expenses in connection therewith;
provided, however, that in the event that Parent determines in good faith that
Purchaser is not aggressively pursuing the development, commercialization, and
any litigation, Parent shall have the right, upon five (5) Business Days written
notice to Purchaser, to assume the pursuit of all or any part of such
development, commercialization, or litigation at Sellers' costs.

          (f) Purchaser shall have the right to assign its rights under the
Odyssey Co-Development Agreement to a third party without consent, provided that
the third party agrees to be bound by the obligations of Purchaser and perform
Purchaser's obligations under that agreement. Purchaser may, at any time,
terminate the Odyssey Co- Development Agreement, in which case Purchaser shall
have no further obligations regarding the Odyssey Product or that agreement, but
shall also waive all rights it received under that agreement.

     3.6 Disputed Statements.

          (a) Purchaser will keep full and accurate books and records relating
to the performance required with respect to its obligations to pay royalties
under this Agreement and its Net Sales. For one (1) year after receipt of a
Lifecycle Products Statement or New Product Statement delivered pursuant to
Section 3.2 or Section 3.2(a) (each, a "Net Sales Statement"), as applicable
(the "Audit Termination Date"), Sellers shall have the right, during regular
business hours and upon reasonable advance notice, to have the books and records
of Purchaser relating to such Net Sales and royalty payments audited no more
frequently than once per year so as to verify the accuracy of Purchaser's
calculation of such Net Sales or royalty payment. If, upon the inspection of the
books and records of Purchaser, Sellers disagree with Purchaser's calculation of
Net Sales or royalty payments set forth in any Net Sales Statement, Sellers may,
prior to the expiration of the Audit Termination Date, deliver written notice to
Purchaser disagreeing with such calculation and setting forth Sellers'
calculation of such amount. Any such notice of disagreement shall specify those
items or amounts as to which Sellers disagree, and Sellers shall be deemed to
have agreed with all other items and amounts contained in the Net Sales
Statement and the calculation of Net Sales included in such Net Sales Statement.
If Sellers do not deliver to

                                       35

<PAGE>

Purchaser a written notice of disagreement prior to the expiration of the Audit
Termination Date, then Sellers shall be deemed to have agreed to such Net Sales
Statement.

          (b) If a notice of disagreement shall be duly delivered pursuant to
Section 3.6(a), Purchaser and Sellers shall, during the ten (10) Business Days
following such delivery, use their commercially reasonable efforts to reach
agreement on the disputed items or amounts in order to determine, as may be
required, the amount of Net Sales of the Lifecycle Products, or New Products, as
applicable, and the royalty payments in connection therewith, which amount shall
not be less than the amount thereof shown in Purchaser's calculation set forth
in the Net Sales Statement nor more than the amount thereof set forth in
Sellers' calculation delivered pursuant to Section 3.6(a). If during such
period, Purchaser and Sellers are unable to reach such agreement, they shall
promptly thereafter cause the Accountant to review this Agreement and the
disputed items or amounts for the purpose of calculating Net Sales of the
Lifecycle Products, or New Products, as applicable, and the amount of the
royalty payments in connection therewith included in such Net Sales Statement
(it being understood that in making such calculation, the Accountant shall be
functioning as an expert and not as an arbitrator). In making such calculation,
the Accountant shall consider only those items or amounts in the Net Sales
Statement and Sellers' calculation of Net Sales included in such Net Sales
Statement as to which Sellers have disagreed. The Accountant shall deliver to
Purchaser and Sellers, as promptly as practicable (but in any case no later than
twenty (20) Business Days from the date of engagement of the Accountant), a
report setting forth such calculation. Such report shall be final and binding
upon Purchaser and Sellers. The cost of such review and report shall be borne
equally by Purchaser on one hand and Sellers on the other hand; provided,
however, that if the Accountant's report is in agreement with either party's
calculations included in the Net Sales Statement, the cost of such review and
report shall be borne solely by the other party.

          (c) Purchaser and Sellers shall, and shall cause their respective
representatives to, cooperate and assist in the preparation of the Net Sales
Statement and the calculation of the amount of Net Sales of the Lifecycle
Products, or New Products, as applicable, and the amount of the royalty payments
in connection therewith and in the conduct of the review referred to in this
Section 3.6(a), including making available, to the extent necessary, books,
records, work papers and personnel.

          (d) If the amount of Net Sales of the Lifecycle Products, or New
Products, as applicable, and the royalty payments in connection therewith, as
determined by the Accountant pursuant to Section 3.6(a), is greater than the
calculation provided for by Purchaser in the applicable Net Sales Statement,
then Purchaser shall promptly pay to Parent an amount equal to the difference
between the Accountant's calculation of such royalty payments and Purchaser's
calculation of such royalty payments.

     3.7 Closing Date Inventory Adjustment.

          (a) As promptly as practicable, but no later than sixty (60) days
after the Closing Date, Purchaser shall cause to be prepared and delivered to
Sellers a statement calculating the Closing Date Inventory (the "Closing Date
Inventory Statement"), including copies of any and all back-up or supporting
data used in the preparation of the Closing Date Inventory Statement.

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<PAGE>

          (b) If Sellers disagree with Purchaser's calculation of the Closing
Date Inventory delivered pursuant to Section 3.7(a), Sellers may, within ten
(10) Business Days after delivery of the Closing Date Inventory Statement,
deliver a written notice to Purchaser disagreeing with such calculation and
setting forth Sellers' calculation of the Closing Date Inventory. Any such
notice of disagreement shall specify those items or amounts as to which Sellers
disagree, and Sellers shall be deemed to have agreed with all other items and
amounts contained in the Closing Date Inventory Statement and the calculation of
Closing Date Inventory delivered pursuant to Section 3.7(a). If Sellers do not
deliver to Purchaser a written notice of disagreement within such ten (10)
Business Day period, then Sellers shall be deemed to have agreed to such the
Closing Date Inventory Statement.

          (c) If a notice of disagreement shall be duly delivered pursuant to
Section 3.7(b), Purchaser and Sellers shall, during the ten (10) Business Days
following such delivery, use their commercially reasonable efforts to reach
agreement on the disputed items or amounts in order to determine, as may be
required, the Closing Date Inventory. If during such period, Purchaser and
Sellers are unable to reach such agreement, they shall promptly thereafter cause
the Accountant to review this Agreement and the disputed items or amounts for
the purpose of calculating Closing Date Inventory. In making such calculation,
the Accountant shall consider only those items or amounts in the Closing Date
Inventory Statement and Sellers' calculation of Closing Date Inventory as to
which Sellers have disagreed. The Accountant shall deliver to Purchaser and
Sellers, as promptly as practicable (but in any case no later than twenty (20)
Business Days from the date of engagement of the Accountant), a report setting
forth such calculation. Such report shall be final and binding upon Purchaser
and Sellers. The cost of such review and report shall be borne equally by
Purchaser on one hand and Sellers on the other hand; provided, however, that if
the Accountant's report is substantially in agreement with either party's
calculations included in the Closing Date Inventory Statement, the cost of such
review and report shall be borne solely by the other party.

          (d) Purchaser and Sellers shall, and shall cause their respective
representatives to, cooperate and assist in the preparation of the Closing Date
Inventory Statement and the calculation of Closing Date Inventory and in the
conduct of the review referred to in this Section 3.7, including the making
available to the extent necessary of books, records, work papers and personnel.

          (e) "Final Closing Date Inventory" means Closing Date Inventory (i) as
shown in Purchaser's calculation delivered pursuant to Section 3.7(a) if no
notice of disagreement with respect thereto is duly delivered pursuant to
Section 3.7(b); or (ii) if such a notice of disagreement is delivered, (A) as
agreed by Purchaser and Sellers pursuant to Section 3.7(c) or (B) in the absence
of such agreement, as shown in the Accountant's calculation delivered pursuant
to Section 3.7(c). If the Final Closing Date Inventory does not include each
item of Inventory and in the minimum quantities listed in Schedule 1.1(b), then
Parent shall be obligated to pay to Purchaser an amount in cash equal to the
Purchaser Closing Date Inventory Adjustment Amount (the "Purchaser Inventory
Payment") within three (3) Business Days after the Final Closing Date Inventory
is determined; provided, however, that if the Final Closing Date Inventory
reflects any item of Inventory in quantities exceeding the minimum quantities
listed in Schedule 1.1(b), then the Purchaser Inventory Payment shall be offset
by an amount equal to the Parent Closing Date Inventory Adjustment Amount (the
"Parent Inventory Payment"); provided,

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<PAGE>

further, however, that if the Parent Inventory Payment exceeds the Purchaser
Inventory Payment, then Purchaser shall not be entitled to the Purchaser
Inventory Payment and Purchaser shall pay to Parent, within three (3) Business
Days after the Final Closing Date Inventory is determined, an amount in cash
equal to the amount that the Parent Inventory Payment exceeds the Purchaser
Inventory Payment. Any payment that any party is obligated to make to the other
party pursuant to this Section 3.7 shall be paid by wire transfer of immediately
available funds into an account designated by such other party; provided,
however, that such other party may (but shall not be obligated to) elect, at any
time, to withdraw the amount of any such payment from the Purchaser's Indemnity
Escrow Fund or the Sellers' Indemnity Escrow Fund, as applicable.

     3.8 Adjustment for Excess Shipments. As promptly as practical, but no later
than sixty (60) days after the Closing Date, Sellers shall cause to be prepared
and delivered to Purchaser a statement calculating the Post-Signing Shipment
Values for each Marketed Product (the "Post-Signing Shipments Statement"),
including any and all back up or supporting data used in the preparation of the
Post-Signing Shipments Statement. If the sum of the Post-Signing Shipment Values
of all of the Marketed Products is greater than the sum of applicable IMS
Product Demand Average Values, then the Sellers shall pay to the Purchaser an
amount in cash equal to the Shipping Adjustment Amount within three (3) Business
Days after the Post-Signing Shipment Statement is delivered. Any payment Sellers
are obligated to make to Purchaser pursuant to this Section 3.8 shall be paid by
Sellers by wire transfer of immediately available funds into an account
designated by Purchaser; provided, however, that Purchaser may (but shall not be
obligated to) elect, at any time, to withdraw the amount of any such payment
from the Sellers' Indemnity Escrow Fund.

     3.9 Payment of Purchase Price.

          (a) On the Closing Date, Purchaser shall pay the Purchase Price (less
Sellers' Indemnity Escrow Amount) to Sellers, which shall be paid by wire
transfer of immediately available funds into an account designated by Sellers.

          (b) On the Closing Date, Purchaser, Sellers and the Escrow Agent shall
enter into the Indemnity Escrow Agreement and Purchaser shall deliver to the
Escrow Agent under the Indemnity Escrow Agreement, by wire transfer of
immediately available funds, Sellers' Indemnity Escrow Amount and Purchaser's
Indemnity Escrow Amount.

                                   ARTICLE IV

                             CLOSING AND TERMINATION

     4.1 Closing Date. Subject to the satisfaction of the conditions set forth
in Sections 10.1 and 10.2 hereof (or the waiver thereof by the party entitled to
waive that condition), the closing of the purchase and sale of the Purchased
Assets and the assumption of the Assumed Liabilities provided for in Article II
hereof (the "Closing") shall take place at the offices of Weil, Gotshal & Manges
LLP located at 767 Fifth Avenue, New York, New York 10153 (or at such other
place as the parties may designate in writing) at 10:00 a.m. (New York City
time) on a date to be specified by the parties, which date shall be no later
than the second (2nd) Business Day after satisfaction or waiver of the
conditions set forth in Article X (other than conditions that by

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<PAGE>

their nature are to be satisfied at the Closing, but subject to the satisfaction
or waiver of such conditions), unless another time or date, or both, are agreed
to in writing by the parties hereto. The date on which the Closing shall be held
is referred to in this Agreement as the "Closing Date." Unless otherwise agreed
by the parties in writing, the Closing shall be deemed effective and all right,
title and interest of Sellers to be acquired by Purchaser hereunder shall be
considered to have passed to Purchaser as of 12:01 a.m. (New York City time) on
the Closing Date.

     4.2 Deliveries by Sellers. At the Closing, Sellers shall deliver to
Purchaser:

          (a) a duly executed bill of sale in the form of Exhibit A hereto;

          (b) duly executed assumption agreement in the form of Exhibit B hereto
and duly executed assignments of the U.S. trademark registrations and
applications included in the Purchased Intellectual Property, in the form
attached hereto as Exhibit D (the "Trademark Assignment Agreement"), and general
assignments of all other Purchased Intellectual Property;

          (c) copies of all consents, waivers and approvals referred to in
Section 10.3(e);

          (d) duly executed affidavits of non-foreign status for each Seller
that comply with Section 1445 of the Code;

          (e) a copy of the Sale Order;

          (f) the officer's certificate required to be delivered pursuant to
Sections 10.1 (a) and 10.1(b);

          (g) a duly executed Manufacturing Agreement;

          (h) a duly executed Services Agreement;

          (i) a duly executed domain name transfer agreement substantially in a
form and substance reasonably satisfactory to Purchase and Sellers (the "Domain
Name Transfer Agreement");

          (j) a duly executed Indemnity Escrow Agreement;

          (k) a duly executed Odyssey Co-Development Agreement;

          (l) product transfer of ownership letters to the FDA substantially in
the form attached hereto as Exhibit J; and

          (m) such other documents, instruments and certificates as Purchaser
may reasonably request.

     4.3 Deliveries by Purchaser. At the Closing, Purchaser shall deliver to
Seller:

          (a) the Purchase Price (less Sellers' Indemnity Escrow Amount);

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<PAGE>

          (b) evidence of the wire transfers referred to in Section 3.9 hereof;

          (c) a duly executed assumption agreement in the form attached hereto
as Exhibit B hereto;

          (d) the officer's certificate required to be delivered pursuant to
Sections 10.2(a) and 10.2(b);

          (e) a duly executed Manufacturing Agreement;

          (f) a duly executed Domain Name Transfer Agreement in a form and
substance reasonably satisfactory to Purchaser and Sellers;

          (g) a duly executed Trademark Assignment Agreement;

          (h) a duly executed Indemnity Escrow Agreement;

          (i) a duly executed Services Agreement;

          (j) a duly executed Odyssey Co-Development Agreement;

          (k) product transfer of ownership letters to the FDA substantially in
the form attached hereto as Exhibit J; and

          (l) such other documents, instruments and certificates as Sellers may
reasonably request.

     4.4 Termination of Agreement. This Agreement may be terminated prior to the
Closing as follows:

          (a) by mutual written consent of Sellers and Purchaser;

          (b) by Purchaser, if any of the conditions to the obligations of
Purchaser set forth in Sections 10.1 and 10.3 shall have become incapable of
fulfillment, other than as a result of a breach by Purchaser of any covenant or
agreement contained in this Agreement, and such condition is not waived by
Purchaser;

          (c) by Sellers, if any condition to the obligations of Sellers set
forth in Sections 10.2 and 10.3 shall have become incapable of fulfillment,
other than as a result of a breach by Sellers of any covenant or agreement
contained in this Agreement, and such condition is not waived by Sellers;

          (d) by Sellers or Purchaser if there shall be in effect a final
nonappealable Order of a Governmental Body of competent jurisdiction
restraining, enjoining or otherwise prohibiting the consummation of the
transactions contemplated hereby; it being agreed that Sellers and Purchaser, as
the case may be, shall promptly appeal any adverse determination which is not
nonappealable (and Sellers and Purchaser, as the case may be, shall use their
commercially reasonable efforts to pursue such appeal);

                                       40

<PAGE>

          (e) by Purchaser, in accordance with Section 3.1;

          (f) by Purchaser, if there is a Material Adverse Effect;

          (g) by Purchaser or Sellers, if the Bankruptcy Court approves a
Restructuring Transaction or an Alternative Transaction;

          (h) by Purchaser, if Sellers have not commenced the Chapter 11 Case
within four (4) Business Days after the date hereof;

          (i) by Purchaser, if the Sellers have not filed with the Bankruptcy
Court the Approval Motion within one (1) Business Day after the date of
commencement of the Chapter 11 Case;

          (j) by Purchaser, if the Bidding Procedures Order has not been entered
by the Bankruptcy Court within thirty-five (35) days after the date of
commencement of the Chapter 11 Case;

          (k) by Purchaser, if the Sale Order has not been entered by the
Bankruptcy Court within seventy (70) days after the date of commencement of the
Chapter 11 Case;

          (l) by Purchaser, if the Bidding Procedures Order (including the
Bidding Procedures) or the Sale Order is modified in any respect without the
consent of Purchaser; provided, however, in the case of the Bidding Procedures
Order, Purchaser shall exercise its reasonable discretion, provided that no such
modification shall be adverse to Purchaser;

          (m) by Purchaser, if (i) the Bankruptcy Court enters an order
appointing a trustee, examiner with expanded powers or responsible officer in
the Chapter 11 Case, (ii) the Chapter 11 Case is converted to a case under
chapter 7 of the Bankruptcy Code or (iii) the Chapter 11 Case is dismissed;

          (n) by Purchaser, if Purchaser shall have sent written notice to
Sellers at least three (3) Business Days prior to the hearing to approve the
Bidding Procedures Order that the condition set forth in Section 10.1(d) has not
been satisfied; or

          (o) by Purchaser, if any secured creditor of either Seller obtains
relief from the stay to foreclose on a significant portion of the Purchased
Assets or Licensed Assets, the effect of which would cause a Material Adverse
Effect.

          Notwithstanding the foregoing, if the Closing shall not have occurred
by the close of business on one hundred eighty (180) days after the date hereof,
this Agreement shall automatically terminate.

     4.5 Payment of Development Costs. If this Agreement is terminated, Sellers
shall pay to Purchaser the Development Costs, if any, on the fifth (5th)
Business Day after such termination, which payment obligation of Sellers shall
be an administrative priority expense under Sections 503(b) and 507(a)(l) of the
Bankruptcy Code. The payment by Sellers to

                                       41

<PAGE>

Purchaser of the Development Costs shall be in addition to the payment of the
Expense Reimbursement and shall not be included in the calculation of the
Expense Reimbursement.

     4.6 Procedure Upon Termination. In the event of termination and abandonment
by Purchaser or Sellers, or both, pursuant to Section 4.4 hereof, written notice
thereof shall forthwith be given to the other party or parties, and this
Agreement shall terminate, and the purchase of the Purchased Assets hereunder
shall be abandoned, without further action by Purchaser or Sellers. If this
Agreement is terminated as provided herein each party shall redeliver all
documents, work papers and other material of any other party relating to the
transactions contemplated hereby, whether so obtained before or after the
execution hereof, to the party furnishing the same.

     4.7 Effect of Termination. In the event that this Agreement is validly
terminated as provided herein, then each of the parties shall be relieved of its
duties and obligations arising under this Agreement after the date of such
termination and such termination shall be without liability to Purchaser or
Seller; provided, however, that the obligations of the parties set forth in
Article XIII and Sections 4.6, 4.7 and 7.1 hereof shall survive any such
termination and shall be enforceable hereunder; provided, further, however, that
nothing in this Section 4.7 shall relieve Purchaser or Sellers of any liability
for a breach of this Agreement prior to the effective date of such termination.

                                    ARTICLE V

                    REPRESENTATIONS AND WARRANTIES OF SELLERS

          Sellers hereby, jointly and severally, represent and warrant to
Purchaser that:

     5.1 Organization and Good Standing.

          Each Seller is duly organized, validly existing and in good standing
under the laws of the State of Delaware and has all requisite power and
authority to own, lease and operate its properties and to carry on its business
as now conducted. Except as set forth in Schedule 5.1 each Seller is duly
qualified or authorized to do business as a foreign company and is in good
standing under the laws of each jurisdiction in which it owns or leases real
property and each other jurisdiction in which the conduct of its business or the
ownership of its properties requires such qualification or authorization, except
where the failure to be so qualified, authorized or in good standing would not
have a Material Adverse Effect. Each Seller has delivered to Purchaser true,
complete and correct copies of its certificate of incorporation and by-laws or
comparable organizational documents as in effect on the date hereof.

     5.2 Authorization of Agreement. Subject to obtaining Bankruptcy Court
approval pursuant to the Sale Order, Sellers have all requisite power, authority
and legal capacity to execute and deliver this Agreement and Sellers and each of
their Subsidiaries have all requisite power, authority and legal capacity to
execute and deliver each other agreement, document, or instrument or certificate
contemplated by this Agreement or to be executed by Sellers in connection with
the consummation of the transactions contemplated by this Agreement (the "Seller
Documents"), to perform their respective obligations hereunder and thereunder
and to

                                       42

<PAGE>

consummate the transactions contemplated hereby and thereby. Subject to
obtaining Bankruptcy Court approval pursuant to the Sale Order, the execution
and delivery of this Agreement and the Seller Documents and the consummation of
the transactions contemplated hereby and thereby have been duly authorized by
all requisite corporate action on the part of Sellers and each of their
Subsidiaries. This Agreement has been, and each of the Seller Documents will be
at or prior to the Closing, duly and validly executed and delivered by Sellers
and each of their Subsidiaries which is a party thereto and (assuming the due
authorization, execution and delivery by the other parties hereto and thereto)
following the approval of this Agreement and the transactions contemplated
hereby by the Bankruptcy Court pursuant to the Sale Order, this Agreement,
constitutes, and each of the Seller Documents when so executed and delivered
will constitute, legal, valid and binding obligations of Sellers, or, as the
case may be, their Subsidiaries enforceable against Sellers or, as the case may
be, their Subsidiaries in accordance with their respective terms, subject to
applicable bankruptcy, insolvency, reorganization, moratorium and similar laws
affecting creditors' rights and remedies generally, and subject, as to
enforceability, to general principles of equity, including principles of
commercial reasonableness, good faith and fair dealing (regardless of whether
enforcement is sought in a proceeding at law or in equity).

     5.3 Board Approval and Recommendation. The Board of Directors of Parent has
(i) determined that this Agreement and the transactions contemplated hereby,
including the purchase of the Purchased Assets by Purchaser in accordance with
the Bidding Procedures, are advisable, fair to and in the best interests of the
Sellers' chapter 11 estates, (ii) determined that an immediate sale of the
Purchased Assets pursuant to Section 363 of the Bankruptcy Code is necessary to
preserve the value of the Purchased Assets, and (iii) approved this Agreement
and the transactions contemplated hereby.

     5.4 Conflicts; Consents of Third Parties.

          (a) Except as a result of the Chapter 11 Case, none of the execution
and delivery by Sellers of this Agreement or by Sellers of the Seller Documents,
the consummation of the transactions contemplated hereby or thereby, or
compliance by Sellers with any of the provisions hereof or thereof will conflict
with, or result in any violation of or default (with or without notice or lapse
of time, or both) under, or give rise to a right of termination, cancellation or
acceleration of any obligation or to loss of a material benefit under, or give
rise to any obligation of Sellers to make any payment under, or to the
increased, additional, accelerated or guaranteed rights or entitlements of any
Person under, or result in the creation of any Liens upon any of the properties
or assets of Sellers under any provision of (i) the certificate of incorporation
and by-laws or comparable organizational documents of Sellers or any Subsidiary;
(ii) subject to entry of the Sale Order, any Purchased Contract; (iii) subject
to entry of the Sale Order, any Order of any court, Governmental Body or
arbitrator applicable to Sellers or any Subsidiary or any of the properties or
assets of Sellers or any Subsidiary as of the date hereof; or (iv) subject to
entry of the Sale Order, any Applicable Law except as set forth on Schedule
5.4(b).

          (b) Other than in connection with the commencement of the Chapter 11
Case, entry of the Bidding Procedures Order and entry of the Sale Order, no
consent, waiver, approval, Order or authorization of, or declaration or filing
with, or notification to, any Person or Governmental Body is required on the
part of Sellers or any Subsidiary (i) in connection with the

                                       43

<PAGE>

execution and delivery of this Agreement or the Seller Documents, the compliance
by Sellers or any Subsidiary with any of the provisions hereof or thereof, the
consummation of the transactions contemplated hereby or the taking by Sellers or
any Subsidiary of any other action contemplated hereby, or (ii) for the
continuing validity and effectiveness immediately following the Closing of any
of the Purchased Assets or Licensed Assets, except for compliance with the
applicable requirements of the HSR Act or as set forth in Schedule 5.4(b).

     5.5 Financial Statements; Projections.

          (a) Sellers have delivered to Purchaser copies of the audited
consolidated balance sheets of Parent as at December 31, 2003 and 2004 and the
related audited consolidated statements of income and of cash flows of Parent
for the fiscal years then ended (such audited statements, including the related
notes and schedules thereto, are referred to herein as the "Financial
Statements"). The Financial Statements have been prepared in accordance with
GAAP consistently applied and present fairly in all material respects the
consolidated financial position, results of operations and cash flows of Parent
as at the dates and for the periods indicated.

          For the purposes hereof, the audited consolidated balance sheet of
Parent as at December 31, 2004 is referred to as the "Balance Sheet" and
December 31, 2004 is referred to as the "Balance Sheet Date."

          (b) Sellers have delivered to Purchaser the unaudited statement of
gross revenues, net revenues and direct costs of the Business for the fiscal
year ended December 31, 2004 and the interim period ended March 31, 2005
(collectively, the "Financial Statements of the Business"). The gross revenues,
net revenues and direct costs included in the Financial Statements of the
Business were prepared in accordance with Parent's applicable accounting
policies, which are consistent with and based upon GAAP, via Parent's compliance
with GAAP, and present fairly in all material respects the gross revenues, net
revenues and direct costs of the Business for the periods indicated.

          (c) Except as disclosed in Schedule 5.5(c), Parent has made all
required filings with the U.S. Securities and Exchange Commission (the "SEC")
since January 1, 2004 through the date hereof. Except as disclosed in Schedule
5.5(c), to the Knowledge of Sellers, as of their respective dates, all such
filings complied as to form in all material respects with the requirements of
the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and the
rules and regulations of the SEC promulgated thereunder applicable to such SEC
filings, and such SEC filings did not contain any untrue statement of a material
fact or omit to state a material fact required to be stated therein or necessary
to make the statements therein, in light of the circumstances under which they
were made, not misleading. Except as disclosed in Schedule 5.5(c), to the
Knowledge of Sellers, the financial statements set forth in such SEC filings
comply as to form in all material respects with applicable accounting
requirements and the published rules and regulations of the SEC promulgated
under the Exchange Act, including Regulation S-X. Except as disclosed in
Schedule 5.5(c), to the Knowledge of Sellers, with respect to each Annual Report
on Form 10-K and each Quarterly Report on Form 10-Q included in such SEC
filings, the financial statements and other financial information included in
such reports fairly present in all material respects the financial condition and
results of operations of Parent as of,

                                       44

<PAGE>

and for, the periods presented in the SEC filings. The reports of Parent's
independent auditors regarding Parent's consolidated financial statements in the
SEC filings have not been withdrawn, supplemented or modified, and none of
Parent or any of its Subsidiaries has received any written communication from
its independent auditors concerning any such withdrawal, supplement or
modification.

     5.6 No Undisclosed Liabilities. Except as disclosed in Schedule 5.6,
neither Sellers nor any of their Subsidiaries have any Indebtedness, obligations
or Liabilities of any kind related to the Business other than those (i) fully
reflected in, reserved against or otherwise described in the Financial
Statements or the notes thereto; (ii) immaterial to Sellers or any Subsidiary
and incurred in the Ordinary Course of Business since December 31, 2004; or
(iii) which would not have or would not reasonably be expected to have a
Material Adverse Effect.

     5.7 Absence of Certain Developments. Except as expressly contemplated by
this Agreement or as set forth in Schedule 5.7, since the Balance Sheet Date (i)
Sellers have conducted the Business only in the Ordinary Course of Business and
(ii) there has not occurred any Material Adverse Effect. Except as set forth in
Schedule 5.7, without limiting the generality of the foregoing, since the
Balance Sheet Date, with respect to only the Business, Purchased Assets and
Licensed Assets:

               (i) Sellers have not made or rescinded any election relating to
     Taxes or settled or compromised any claim, action, suit, litigation,
     proceeding, arbitration, investigation, audit or controversy relating to
     Taxes to the extent such election, settlement or compromise would have any
     material post Closing effect that would be binding on Purchaser for taxable
     periods (or portions thereof) beginning on or after the Closing Date;

               (ii) neither Sellers nor any Subsidiary has amended, modified,
     canceled, terminated, relinquished, waived or released any Purchased
     Contract or right except in the Ordinary Course of Business and which, in
     the aggregate, would not have a Material Adverse Effect;

               (iii) neither Sellers nor any Subsidiary has instituted or
     settled any material Legal Proceeding relating to the Purchased Assets or
     the Licensed Assets that would result in a Material Adverse Effect;

               (iv) Sellers have not granted any license or sublicense of any
     rights under or with respect to any Purchased Intellectual Property; or

               (v) Sellers have not agreed, committed, arranged or entered into
     any understanding to do anything set forth in this Section 5.7.

     5.8 Taxes.

          (a) With respect to the Business, the Purchased Assets and the
Licensed Assets, (i) all material Tax Returns required to be filed by or on
behalf of Sellers or any affiliated group of which Sellers are or were a member
have been duly and timely filed with the appropriate Taxing Authority in all
jurisdictions in which such Tax Returns are required to be filed (after giving
effect to any valid extensions of time in which to make such filings), and all

                                       45

<PAGE>

such Tax Returns are true, complete and correct in all material respects; and
(ii) all material Taxes payable by or on behalf of Sellers or any Affiliated
Group of which Sellers are or were a member have been fully and timely paid.

          (b) Sellers have timely paid or caused to be paid all Taxes due with
respect to the Purchased Assets, Licensed Assets or the Business, the
non-payment of which would result in a Lien on any Purchased Asset or Licensed
Assets or would result in Purchaser becoming liable or responsible therefor.

          (c) All deficiencies asserted or assessments made as a result of any
examinations by any Taxing Authority of the Tax Returns related to the Purchased
Assets, the Licensed Assets or the Business have been fully paid, and, to the
knowledge of Sellers, there are no other audits or investigations by any Taxing
Authority in progress, nor have Sellers received any written notice from any
Taxing Authority that it intends to conduct such an audit or investigation
related to the Purchased Assets or the Business.

          (d) There is no Purchased Contract covering any Person that,
individually or collectively, could give rise to the payment of any amount that
would not be deductible by Purchaser, Sellers or any of their respective
Affiliates by reason of Section 280G of the Code.

          (e) Neither Seller is a foreign person within the meaning of Section
1445 of the Code.

          (f) No power of attorney with respect to any Tax matter is currently
in force with respect to the Purchased Assets, the Licensed Assets or the
Business that would, in any manner, bind, obligate, or restrict Purchaser.

          (g) Sellers have not executed or entered into any agreement with, or
obtained any consents or clearances from, any Taxing Authority, or have been
subject to any ruling guidance specific to any Seller, that would be binding on
Purchaser for any taxable period (or portion thereof) ending on or after the
Closing Date.

     5.9 Title to Purchased Assets. Sellers own and have good title to each of
the Purchased Assets and the Licensed Assets, and at the Closing, Sellers shall
convey each of the Purchased Assets free and clear of all Liens.

     5.10 Intellectual Property.

          (a) Schedule 5.10 sets forth an accurate and complete list of all
Patents, registered Trademarks, pending applications for registrations of any
Trademarks, registered Copyrights, and pending applications for registration of
Copyrights, owned or filed by Sellers or any of their Subsidiaries included in
the Purchased Intellectual Property, including the jurisdictions in which each
such item has been issued or registered or in which any such application for
such issuance and registration has been filed.

          (b) To the actual knowledge of Sellers: (i) the Purchased Intellectual
Property does not; (ii) the manufacturing, licensing, importation, offer for
sale, sale, use, marketing, co-marketing, promotion and co-promotion of the
Marketed Products as such products are currently

                                       46

<PAGE>

manufactured, licensed, imported, offered for sale, sold, used, marketed,
co-marketed, promoted and co-promoted does not; (iii) the manufacturing,
licensing, importation, offer for sale, sale, use, marketing, co-marketing,
promotion and co-promotion of the Pipeline Products as they exist as of the date
hereof will not; and (iv) the manufacturing, licensing, importation, offer for
sale, sale, use, marketing, co- marketing, promotion and co-promotion of the
Lynxorb Product and the Darvocet-N Suspension Product as they are currently
contemplated to be developed will not constitute an infringement, unauthorized
use or misappropriation of any patent, copyright, trademark, trade secret or
other similar right, of any Person (including, without limitation, pursuant to
any non-disclosure agreements or obligations to which Sellers or any of their
present or former employees is a party). To the actual knowledge of Sellers, the
manufacturing, licensing, importation, offer for sale, sale, use, marketing,
co-marketing, promotion and co-promotion of the Darvocet-N XR Product and the
Odyssey Product as they each are currently contemplated to be developed does not
and will not constitute infringement, unauthorized use or misappropriation of
any copyright, trademark, trade secret or similar non-patent right of any Person
(including, without limitation, pursuant to any non-disclosure agreements or
obligations to which Sellers or any of their present or former employees is a
party). Subject to the consents referred to in Section 5.4(b) being obtained for
the Purchased Contracts, the Purchased Intellectual Property, the Licensed
Assets, the Purchased Assets, and the transactions contemplated by the
Manufacturing Agreement and the Services Agreement include all of the
Intellectual Property rights necessary to enable Sellers to conduct the Business
in the manner in which such Business is currently being conducted as of the date
hereof. The consummation of the transactions contemplated hereby will not result
in the loss or impairment of Purchaser's right to own or use any of the
Purchased Intellectual Property.

          (c) Except as set forth in Schedule 5.10, other than the Purchased
Intellectual Property and Licensed Assets, neither Sellers nor any of their
Subsidiaries own or are exclusive licensees under any Intellectual Property
necessary for the manufacturing, licensing, importation, offer for sale, sale,
use, marketing, co-marketing, promotion and co-promotion of the Marketed
Products, the Pipeline Products or the Odyssey Product and, to the actual
knowledge of Sellers, there are no Intellectual Property rights owned by or
exclusively licensed to Sellers useful in connection with the same.

          (d) Except as set forth in Schedule 5.10, neither Sellers nor any of
their Subsidiaries are obligated to pay any royalties, fees or similar
obligations to any owner, licensor of, or other claimant for the use of the
Purchased Intellectual Property.

          (e) Schedule 5.10 sets forth a complete and accurate list of all: (i)
Intellectual Property Licenses; and (ii) material Contracts to which Sellers or
any of their Subsidiaries are a party containing an agreement to indemnify any
other Person against any claim of infringement by the Purchased Intellectual
Property.

          (f) Except as set forth in Schedule 5.10 or except as would not have
or would not reasonably be expected to have a Material Adverse Effect, (i) each
of the Intellectual Property Licenses is in full force and effect and
constitutes a valid and binding obligation of Sellers and/or their Subsidiaries,
enforceable against them in accordance with its terms, subject to applicable
bankruptcy, insolvency, reorganization, moratorium and similar laws affecting
creditors' rights and remedies generally and subject, as to enforceability, to
general principles of

                                       47
<PAGE>

equity (regardless of whether enforcement is sought in a proceeding at law or in
equity), (ii) except as a result of the Chapter 11 Case, neither Sellers nor any
Subsidiary is in default under any Intellectual Property License, nor, to the
Knowledge of Sellers, is any other party to an Intellectual Property License in
default thereunder, (iii) to the Knowledge of Sellers, no event has occurred
that with the lapse of time or the giving of notice or both would constitute a
default thereunder, and (iv) no party to any of the Intellectual Property
Licenses has exercised any termination rights with respect thereto.

          (g) Except as set forth in Schedule 5.10, no trade secret or any other
non-public, proprietary information material to the Marketed Products, the
Pipeline Products or the Odyssey Product has been authorized to be disclosed or,
to the Knowledge of Sellers, has been actually disclosed by Sellers or any of
their Subsidiaries to any employee or any third party other than pursuant to a
non-disclosure agreement restricting the disclosure and use of the Purchased
Intellectual Property. Sellers have taken commercially reasonable security
measures to protect the secrecy, confidentiality and value of all material trade
secrets and other confidential information included in the Purchased
Intellectual Property, including invention disclosures not covered by any
patents owned or patent applications filed by Sellers.

          (h) To the actual knowledge of Sellers, no Person is infringing,
violating, misusing or misappropriating any Purchased Intellectual Property.

          (i) Except as set forth in the Parent's SEC filings or Schedule 5.10,
as of the date hereof, no Legal Proceedings are pending or, to the actual
knowledge of Sellers, threatened in writing (i) against the Sellers or any of
their Subsidiaries (A) claiming infringement, unauthorized use, or violation of
any other Person's Intellectual Property with respect to the Marketed Products
or the Pipeline Products, (B) challenging the ownership, use, validity or
enforceability of, any Purchased Intellectual Property or Licensed Assets, or
(ii) against any third Person charging that such third Person is infringing,
violating, misusing or misappropriating any Purchased Intellectual Property or
Licensed Assets of Sellers. To the Knowledge of Sellers, all Patents and
applications or registrations for Trademarks included in the Purchased
Intellectual Property or Licensed Assets have been appropriately prosecuted,
registered, filed, and maintained consistent with all applicable US patent and
trademark laws and rules, including determination of inventorship and citation
of material prior art references.

          (j) Schedule 5.10 sets forth the true and complete list of all
contributors to the science of all potentially claimed subject matter contained
within the Darvocet-N XR EDM and Lynxorb Know How, together with the identity of
their respective inventions. Except as set forth in Schedule 5.10, to the
Knowledge of Sellers, no present or former employee has any right, title, or
interest, directly or indirectly, in whole or in part, in any Purchased
Intellectual Property.

     5.11 Regulatory Status.

          (a) Sellers are the lawful holder of the Marketing Authorizations,
Azathioprine ANDA, Purchased INDs and Purchased DMFs.

          (b) Except as otherwise set forth in Schedule 5.11, all of the
Marketing Authorizations and the Azathioprine ANDA are in full force and effect
and, to the Knowledge of

                                       48
<PAGE>

Sellers, all of the Marketing Authorizations and the Azathioprine ANDA have been
duly and validly issued. Except as otherwise set forth in Schedule 5.11, there
is no Legal Proceeding by any Governmental Body pending or, to the Knowledge of
Sellers, threatened seeking the revocation or suspension of any of the Marketing
Authorizations or the Azathioprine ANDA.

          (c) Except as set forth in Schedule 5.11, to the Knowledge of Sellers
there is no information suggesting that the Marketed Products that are the
subject of an NDA or ANDA cannot be marketed in the Territory pursuant to the
applicable Marketing Authorization or the Azathioprine ANDA. Sellers do not
represent and warrant that the FDA will not, at some future date, require the
submission of a new drug application, abbreviated new drug application, other
regulatory approval or additional information for Marketed Products marketed
without an approved new drug application or abbreviated new drug application, or
require the submission of additional information for any other Marketed
Products.

          (d) Except as set forth in Schedule 5.11, to the Knowledge of Sellers
there are no facts which are reasonably likely to cause (i) market withdrawal,
recall or suspension of any of the Marketed Products, (ii) a change in the
marketing classification of any of the Marketed Products, (iii) a material
change in the labeling of any of the Marketed Products or (iv) a termination or
suspension of marketing of any of the Marketed Products.

          (e) Except as set forth in Schedule 5.11, Sellers have made available
to Purchaser all (i) outstanding post-approval commitments to the FDA; (ii)
adverse drug experience information, (iii) customer complaints, (iv) files with
respect to investigations of complaints, (v) FDA adverse event reports and (vi)
reports of trends of adverse events, in each case to the extent relating to the
Marketed Products and to the extent that any of the foregoing is in Sellers'
possession. Sellers have made available to Purchaser all preclinical, clinical
and validation data and any risk assessments in each Sellers' possession that
have been generated to demonstrate the safety and/or effectiveness of each of
the Marketed Products.

          (f) Except as set forth in Schedule 5.11, Sellers (only with respect
to the operation of the Business), and the Marketed Products (including the
labeling thereof) are in compliance with Applicable Law, except where the
failure to be in compliance would not, individually or in the aggregate,
reasonably be expected to have a Material Adverse Effect. Except as set forth in
Schedule 5.11, to the Knowledge of Sellers there are no facts which furnish any
reasonable basis for any notice of adverse findings, warning or other regulatory
letters or sanctions, Section 305 notices, or other similar communication.
Except as set forth in Schedule 5.11, to the Knowledge of Sellers there are no
misstatements or material omissions relating to the Marketed Products in any
regulatory submission or other document required to be maintained by Applicable
Law and the accuracy of its regulatory submissions has not been contested by any
Governmental Body.

          (g) No employee or officer of Sellers, or to the Knowledge of Sellers,
any other Person, including any clinical investigator, involved in any services
in connection with the Products was debarred or otherwise deemed to be
ineligible to provide services in connection with any of the Products at the
time such services were provided to Sellers.

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          (h) Sellers and their respective employees, and, to the Knowledge of
Sellers, all contract manufacturers, packagers, and other Persons involved in
the manufacture, processing, testing, promoting or advertising of the Marketed
Products are in compliance with all applicable FDA regulations with respect to
the Marketed Products, except to the extent any noncompliance with such
applicable FDA regulations would not reasonably be expected to have a Material
Adverse Effect.

          (i) Except as otherwise set forth in Schedule 5.11, all filings and
notices required to be delivered to any Governmental Body with respect to any of
the Marketed Products have been made on a timely basis, except where the failure
to make such filings and notices on a timely basis would not, individually or in
the aggregate, reasonably be expected to have a Material Adverse Effect.

          (j) Sellers (with respect to the Business) and the Marketed Products
are in compliance with the Federal Controlled Substances Act and applicable DEA
and state regulations, including, but not limited to, record keeping, reporting,
registration, security, labeling, and quota requirements, except where the
failure to be in compliance would not, individually or in the aggregate,
reasonably be expected to have a Material Adverse Effect.

     5.12 Material Contracts. Schedule 5.12 sets forth each material Contract to
which either Seller is currently a party that (i) relates to the manufacture,
marketing, distribution, licensing or sale of any of the Marketed Products; (ii)
has been entered into with any Governmental Body with respect to the
manufacture, marketing, distribution, licensing or sale of the Marketed
Products; (iii) contains covenants not to compete or otherwise restricts
Sellers' rights to manufacture, market, distribute, license or sell the Marketed
Products, the Odyssey Products or any Pain Products; or (iv) provides for
coupons, rebates, chargebacks, promotions, discounts or advertising of any of
the Products. Except as set forth in Schedule 5.12, each such Purchased Contract
is in full force and effect, constitutes a valid and binding obligation of each
Seller party thereto and, to the Knowledge of Sellers, the other parties
thereto, and is legally enforceable against the applicable Seller party thereto
and, to the Knowledge of Sellers, the other parties thereto, in accordance with
its terms, except as such enforceability may be limited by applicable
bankruptcy, insolvency, moratorium, reorganization, or similar laws from time to
time in effect which affect the enforcement of creditors' rights generally.
Except as disclosed in Schedule 5.12, neither Seller is in material breach or
default under any such Purchased Contract to which it is a party and, to the
Knowledge of Sellers, no other party to any of such Purchased Contracts is in
material breach or default in any material respect thereunder. To the Knowledge
of Sellers, no party to any of the Purchased Contracts has exercised any
termination rights with respect thereto. Sellers have delivered or otherwise
made available to Purchaser true, correct and complete copies of all of the
Purchased Contracts, together with all amendments, modifications or supplements
thereto.

     5.13 Labor. Neither Sellers nor any of their Subsidiaries is a party to any
labor or collective bargaining agreement and there are no labor or collective
bargaining agreements which pertain to employees of Sellers or any of their
Subsidiaries.

     5.14 Litigation. Except as set forth in Schedule 5.14 and except for the
contemplated Chapter 11 Case, there is no suit, action, proceeding,
investigation (to the Knowledge of Sellers

                                       50

<PAGE>

as of the date hereof), claim or order pending or, to the Knowledge of Sellers,
threatened against Sellers or any of their Subsidiaries (or to the Knowledge of
Sellers, pending or threatened, against any of the officers, directors, members
or key employees of Sellers or any of their Subsidiaries with respect to their
business activities on behalf of Seller), or to which any Seller or any of their
Subsidiaries is otherwise a party, which, if adversely determined, would have a
Material Adverse Effect, before any Governmental Body; nor to the Knowledge of
Sellers is there any reasonable basis for any such action, proceeding, or
investigation. Other than the Chapter 11 Case, neither Sellers nor any
Subsidiary is subject to any Order of any Governmental Body except to the extent
the same could not reasonably be expected to have a Material Adverse Effect.

     5.15 Compliance with Laws. Except as set forth in Schedule 5.15, Sellers
are in compliance in all material respects with all Applicable Laws of any
Governmental Body applicable to the Business. Neither Sellers nor any of their
Subsidiaries has received any written notice of or been charged with the
violation of any Applicable Laws which would reasonably be expected to have a
Material Adverse Effect. To the Knowledge of Sellers, neither Sellers nor any of
their Subsidiaries is under investigation with respect to the violation of any
Applicable Laws that would reasonably be expected to have a Material Adverse
Effect and there are no facts or circumstances which could form the basis for
any such violation.

     5.16 Environmental Matters. Except as set forth in Schedule 5.16 hereto or
as would individually or in the aggregate, not have a Material Adverse Effect:

          (a) the operations of Sellers and each of their Subsidiaries, with
respect to the Business, are and have been in compliance with all applicable
Environmental Laws, which compliance includes obtaining, maintaining in good
standing and complying with all Environmental Permits necessary to operate the
Business and no action or proceeding is pending or, to the Knowledge of Sellers,
threatened to revoke, modify or terminate any such Environmental Permit, and, to
the Knowledge of Sellers, no facts, circumstances or conditions currently exist
that could adversely affect such continued compliance with Environmental Laws
and Environmental Permits;

          (b) with respect to the Business, neither Sellers nor any of their
Subsidiaries is the subject of any outstanding written order or Contract with
any Governmental Body or Person respecting (i) Environmental Laws, (ii) Remedial
Action or (iii) any Release or threatened Release of a Hazardous Material;

          (c) no claim has been made or is pending or, to the Knowledge of
Sellers, threatened against Sellers nor any of its Subsidiaries, alleging, with
respect to the Business, that either or both Sellers, or any of its
Subsidiaries, may be in violation of any Environmental Law or any Environmental
Permit or may have any liability under any Environmental Law; and

          (d) the transactions contemplated hereunder do not require the consent
of or filings with any Governmental Body with jurisdiction over Sellers with
respect to environmental matters.

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     5.17 Insurance. Set forth in Schedule 5.17 is a list of all product
liability insurance relating to the Business, setting forth, in respect of each
such policy, the policy name, policy number, carrier, term, type of coverage and
annual premium. Except as noted on Schedule 5.17, to Seller's Knowledge all such
product liability insurance will remain in full force and effect.

     5.18 Inventories. The Inventory has been manufactured in material
compliance with United States current good manufacturing practices (as set forth
in 21 C.F.R. 210 and 211) and in accordance with relevant product specifications
used by Sellers at the date of manufacture. The inventories of the Business set
forth in the Balance Sheet were properly stated therein in accordance with GAAP
consistently applied. Adequate reserves have been reflected in the Balance Sheet
for obsolete, excess, damaged or otherwise unusable inventory, which reserves
were calculated in a manner consistent with past practice and in accordance with
GAAP consistently applied. Schedule 5.18 sets forth the quantities of Inventory
that the Sellers in good faith estimate will be on hand at June 30, July 31,
August 31, and September 30, 2005. The inventories and related reserves were
prepared from Sellers' books and records, which books and records are correct
and complete in all material respects.

     5.19 Customer.

          (a) Schedule 5.19(a) sets forth a list of the ten (10) largest
customers with respect to the Marketed Products, as measured by the dollar
amount of invoices therefrom or thereby, during each of the fiscal years ended
December 31, 2003 and December 31, 2004, showing the approximate total sales by
Sellers to each such customer during such period.

          (b) Except as set forth in Schedule 5.19(b) since December 31, 2004
through the date hereof, no customer listed on Schedule 5.19(a) has terminated
its relationship with Sellers or any of their Subsidiaries or materially reduced
or changed the pricing or other terms of its business with Sellers or any of
their Subsidiaries and, to the Knowledge of Sellers, no customer listed on
Schedule 5.19(a) has notified Sellers that it intends to terminate or materially
reduce or change the pricing or other terms of its business with Sellers or any
of their Subsidiaries, in each case which termination or notification would
reasonably be expected to have a Material Adverse Effect.

     5.20 Product Warranty; Product Liability.

          (a) Except as set forth in Schedule 5.20, each product manufactured,
sold or delivered by Sellers or any of their Subsidiaries in conducting the
Business has been in material conformity with applicable product specifications
and all express warranties. Neither Sellers nor any of their Subsidiaries has
any liability for replacement of any such products or other damages in
connection therewith or any other customer or product obligations not reserved
against on the Balance Sheet. Neither Sellers nor any of their Subsidiaries has
sold any products in connection with the Business that included a warranty for a
period of longer than the applicable expiration date for such products.

          (b) Neither Sellers nor any of their Subsidiaries have committed any
act or failed to commit any act, which would result in, and there has been no
occurrence which would give rise to or form the basis of, any product liability
or liability for breach of warranty (whether

                                       52

<PAGE>

covered by insurance or not) on the part of Sellers or any of their Subsidiaries
with respect to Marketed Products.

     5.21 Financial Advisors. Except as set forth in Schedule 5.21, no Person
has acted, directly or indirectly, as a broker, finder or financial advisor for
Sellers or any of their Subsidiaries in connection with the transactions
contemplated by this Agreement and no Person is entitled to any fee or
commission or like payment in respect thereof.

     5.22 FDA Indications. Sellers have not received any written or oral
indication from the FDA that a factorial design study (being a study in which
the Darvocet-N XR Product is required to be compared against one or more of its
ingredients alone) will be required for FDA approval of the Darvocet-N XR
Product.

     5.23 Laboratory Notebooks. The copies of the Notebooks included in the
Purchased Assets, which shall be provided at Purchaser's expense, shall be
identical copies of the portions of the Notebooks for which copies are provided
by Sellers to Purchaser and no information has been removed or deleted from such
copies with respect to any Purchased Intellectual Property or Licensed Assets as
they relate to the Marketed Products, Pipeline Products and Odyssey Products.

     5.24 No Other Representations and Warranties. Purchaser acknowledges that
except as expressly provided in this Agreement, (A) Sellers make no
representation or warranty of any kind whatsoever or by operation of law, by
statute or otherwise, and specifically disclaim any representation or warranty
with respect to any forward-looking projections, forecasts, budgets, financial
data or any other information (written or oral) with respect to the Business,
the Purchased Assets, the Licensed Assets, or any other matter, including those
supplied in the Confidential Information Memorandum distributed by Rothschild,
Inc. or presented in due diligence, and the Purchaser takes full responsibility
for making its own evaluation of such matters, and (b) Sellers specifically
disclaim any and all implied or statutory warranties, including, without
limitation, any warranty of merchantability, warranty of fitness for a
particular purpose, warrant of noninfringement or warranty of title.

                                   ARTICLE VI

                   REPRESENTATIONS AND WARRANTIES OF PURCHASER

          Purchaser hereby represents and warrants to Sellers that:

     6.1 Organization and Good Standing. Purchaser is a corporation duly
organized, validly existing and in good standing under the laws of the State of
Delaware.

     6.2 Authorization of Agreement. Purchaser has full corporate power and
authority to execute and deliver this Agreement and each other agreement,
document, instrument or certificate contemplated by this Agreement or to be
executed by Purchaser in connection with the consummation of the transactions
contemplated hereby and thereby (the "Purchaser Documents"), and to consummate
the transactions contemplated hereby and thereby. The execution, delivery and
performance by Purchaser of this Agreement and each Purchaser Document have been
duly authorized by all necessary corporate action on behalf of Purchaser.

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This Agreement has been, and each Purchaser Document will be at or prior to the
Closing, duly executed and delivered by Purchaser and (assuming the due
authorization, execution and delivery by the other parties hereto and thereto)
this Agreement constitutes, and each Purchaser Document when so executed and
delivered will constitute, legal, valid and binding obligations of Purchaser,
enforceable against Purchaser in accordance with their respective terms, subject
to applicable bankruptcy, insolvency, reorganization, moratorium and similar
laws affecting creditors' rights and remedies generally, and subject, as to
enforceability, to general principles of equity, including principles of
commercial reasonableness, good faith and fair dealing (regardless of whether
enforcement is sought in a proceeding at law or in equity).

     6.3 Conflicts; Consents of Third Parties.

          (a) Except as set forth in Schedule 6.3 hereto, neither of the
execution and delivery by Purchaser of this Agreement and of the Purchaser
Documents, nor the compliance by Purchaser with any of the provisions hereof or
thereof will (i) conflict with, or result in the breach of, any provision of the
certificate of incorporation or bylaws of Purchaser, (ii) conflict with,
violate, result in the breach of, or constitute a default under any note, bond,
mortgage, indenture, license, agreement or other obligation to which Purchaser
is a party or by which Purchaser or its properties or assets are bound or (iii)
violate any statute, rule, regulation or Order by which Purchaser is bound,
except, in the case of clauses (ii) and (iii), for such violations, breaches or
defaults as would not, individually or in the aggregate, have a material adverse
effect on the ability of Purchaser to consummate the transactions contemplated
by this Agreement.

          (b) No consent, waiver, approval, Order, Permit or authorization of,
or declaration or filing with, or notification to, any Person or Governmental
Body is required on the part of Purchaser in connection with the execution and
delivery of this Agreement or Purchaser Documents or the compliance by Purchaser
with any of the provisions hereof or thereof, except for compliance with the
applicable requirements of the HSR Act.

     6.4 Litigation. There are no Legal Proceedings pending or, to the knowledge
of Purchaser, threatened that are reasonably likely to prohibit or restrain the
ability of Purchaser to enter into this Agreement or consummate the transactions
contemplated hereby.

     6.5 Financial Advisors. Except as set forth in Schedule 6.5, no Person has
acted, directly or indirectly, as a broker, finder or financial advisor for
Purchaser in connection with the transactions contemplated by this Agreement and
no Person is entitled to any fee or commission or like payment in respect
thereof.

     6.6 Financing. On the date hereof, Purchaser has obtained an executed
commitment letter or executed commitment letters (collectively, the "Commitment
Letters") for the financing of the consummation of the transactions contemplated
hereunder. The obligations to fund the commitments under the Commitment Letters
are not subject to any condition, other than the conditions in the Commitment
Letters. Copies of such Commitment Letters, which have been provided to Sellers,
have been duly executed by Purchaser and each other Person party thereto, and
have not been amended, modified, withdrawn, terminated or replaced. There are no
fees, expense reimbursement obligations, or other amounts that are required to
be paid by Purchaser prior to the Closing under or in respect of the Commitment
Letters that are unpaid. None of the

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<PAGE>

lenders or investors thereunder have notified Purchaser of its intention to
terminate its commitment under its Commitment Letter or not to provide in full
the financing contemplated thereby. Purchaser has provided to Sellers a chart
showing a reasonably detailed breakdown of the contemplated sources and uses of
such financing as of the date of this Agreement.

                                   ARTICLE VII

                            BANKRUPTCY COURT MATTERS

     7.1 Approval of Break-Up Fee and Expense Reimbursement.

          (a) Sellers acknowledge and agree that Purchaser has expended
considerable time and expense in connection with this Agreement and the
negotiation thereof and the identification and quantification of assets of
Sellers. In consideration therefor, Sellers shall file with and seek the
approval of the Bankruptcy Court of the Approval Motion, including the Break-Up
Fee and Expense Reimbursement, and the entry by the Bankruptcy Court of the
Bidding Procedures Order approving the payment of the Break-Up Fee in an amount
equal to Five Million Two Hundred Fifty Thousand Dollars ($5,250,000) and the
Expense Reimbursement in an amount not to exceed One Million Five Hundred
Thousand Dollars ($1,500,000) (not including any amounts previously paid by
Sellers) for Purchaser's reasonable out-of-pocket documented expenses incurred
in connection with the transactions contemplated hereby and the financing
thereof and deeming the Break-Up Fee and the Expense Reimbursement as
administrative priority expenses under Sections 503(b) and 507(a)(1) of the
Bankruptcy Code.

          (b) Sellers shall pay to Purchaser the Expense Reimbursement on the
first (1st) Business Day after the earlier to occur of (i) Purchaser's
termination of this Agreement pursuant to Section 4.4(e) through Section 4.4(m)
or Section 4.4(o) and (ii) any of the events specified in Section 7.1(c).

          (c) Sellers shall pay to Purchaser the Expense Reimbursement (unless
previously paid to Purchaser in accordance with Section 7.1(b)) and the Break-Up
Fee on the first (1st) Business Day after the earlier to occur of:

               (i) the Bankruptcy Court enters an order approving an Alternative
     Transaction;

               (ii) Outside of the Bidding Procedures, Sellers consummate an
     Alternative Transaction, provided that Sellers have entered into an
     agreement for such Alternative Transaction on or prior to twelve (12)
     months following the date of termination of this Agreement.

          (d) If on or prior to twelve (12) months following the date of
termination of this Agreement Sellers file with the Bankruptcy Court a
Restructuring Transaction or enter into a Restructuring Transaction, Sellers
shall pay to Purchaser, on the first (1st) Business Day after consummation of
such Restructuring Transaction, the Expense Reimbursement and 50% of the
Break-Up Fee (in each case if not previously paid to Purchaser in accordance
with Section 7.1(b)).

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<PAGE>

     7.2 Bidding Procedures. Not later than the date that is one (1) Business
Day following commencement of the Chapter 11 Case, Sellers shall file the
Approval Motion seeking approval of the Bidding Procedures Order, including the
Bidding Procedures, and the Sale Order with the Bankruptcy Court. No later than
thirty-five (35) days after the date of the commencement of the Chapter 11 Case,
Sellers shall obtain entry by the Bankruptcy Court of the Bidding Procedures
Order (with such changes thereto as Purchaser shall approve or request in its
reasonable discretion, which changes shall not be adverse to Purchaser). Sellers
shall comply with all of the terms and conditions contained in the Bidding
Procedures, including the occurrence of the events by the dates and times listed
therein which are expressly incorporated by reference herein as if set forth at
length. Sellers agree to make promptly any filings, to take all actions and to
obtain entry of the Bidding Procedures Order and the Sale Order and any and all
other approvals and orders necessary or appropriate for the consummation of the
transactions contemplated hereby.

     7.3 Non-Solicitation Period.

          (a) From the time of Sellers' and Purchaser's execution and delivery
of this Agreement until the Bankruptcy Court's entry of the Bidding Procedures
Order (the "Non-Solicitation Period"), Sellers shall not, nor shall they
authorize or permit any Affiliate to, nor shall they authorize or permit any
officer, director, manager or employee of, or any investment banker, attorney or
other advisor, agent or representative of, Sellers or any Subsidiary
(collectively, "Seller Representatives") to solicit or otherwise encourage any
entity with respect to the submission of an Alternative Transaction or negotiate
the terms of an Alternative Transaction. Sellers shall not execute any
Alternative Transaction prior to the Bankruptcy Court's entry of the Bidding
Procedures Order.

          (b) Following entry of the Bidding Procedures Order until the bid
deadline set forth therein, Sellers and Seller Representatives shall not be
subject to any restrictions with respect to the solicitation or encouragement of
any entity concerning the potential or actual submission of a qualified bid in
accordance with the Bidding Procedures; provided, however, that within
twenty-four (24) hours after Sellers' receipt of any offer for an Alternative
Transaction, Sellers must deliver to Purchaser by facsimile transmission or same
day courier service true and complete copies of all documents related to any
such Alternative Transaction.

          (c) To the extent the Bidding Procedures Order is inconsistent with
the terms of this Agreement, the Bidding Procedures Order shall control.

     7.4 Bankruptcy Court Approval.

          (a) At least twenty-five (25) days prior to the hearing approving the
Sale Order, Sellers shall serve a copy of the Approval Motion (along with a copy
of the proposed Sale Order and the Bidding Procedures Order) on each
jurisdiction where the Purchased Assets are subject to Tax.

          (b) Sellers shall obtain entry by the Bankruptcy Court of the Sale
Order no later than seventy (70) days after the date of commencement of the
Chapter 11 Case.

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<PAGE>

          (c) If the Bidding Procedures Order or Sale Order or any other orders
of the Bankruptcy Court relating to this Agreement shall be appealed by any
party (or a petition for certiorari or motion for reconsideration, amendment,
clarification, modification, vacation, stay, rehearing or reargument shall be
filed with respect to any such order), Sellers shall diligently defend against
such appeal, petition or motion and shall use their reasonable best efforts to
obtain an expedited resolution of any such appeal, petition or motion.

          (d) Sellers shall not make any filing with the Bankruptcy Court or any
other court or Governmental Body with respect to the Bidding Procedures Order or
Sale Order without the consent of Purchaser, which consent shall not be
unreasonably withheld or delayed.

          (e) Sellers shall cooperate with Purchaser and its representatives in
connection with the Sale Order, the Bidding Procedures Order and the bankruptcy
proceedings in connection therewith. Such cooperation shall include, but not be
limited to, consulting with Purchaser at Purchaser's reasonable request
concerning the status of such proceedings and providing Purchaser with copies of
requested pleadings, notices, proposed orders and other documents relating to
such proceedings as soon as reasonably practicable prior to any submission
thereof to the Bankruptcy Court. Sellers further covenant and agree that the
terms of any plan it submits to the Bankruptcy Court for confirmation shall not
conflict with, supersede, abrogate, nullify or restrict the terms of this
Agreement, or in any way prevent or interfere with the consummation or
performance of the transactions contemplated by this Agreement, including,
without limitation, any transaction contemplated by or approved pursuant to the
Sale Order or the Bidding Procedures Order.

          (f) Notwithstanding anything to the contrary herein, neither Purchaser
nor Sellers shall be prohibited or otherwise restrained from making any filing
with the Bankruptcy Court to challenge or object to the entry of an order by the
Bankruptcy Court approving the entry by Sellers into an Alternative Transaction
or Restructuring Transaction; provided, that nothing herein shall grant
Purchaser standing to the extent that Purchaser would not otherwise have
standing under Applicable Law.

                                  ARTICLE VIII

                                    COVENANTS

     8.1 Access to Information. Sellers agree that, prior to the Closing Date,
Purchaser shall be entitled, through its officers, employees and representatives
(including, without limitation, its legal advisors and accountants), to make
such investigation of the properties, businesses and operations of Sellers and
such examination of the books, records and financial condition of Sellers as it
reasonably requests and to make extracts and copies of such books and records.
Any such investigation and examination shall be conducted during regular
business hours and under reasonable circumstances, and Sellers shall cooperate
fully therein. No investigation by Purchaser prior to or after the date of this
Agreement shall diminish or obviate any of the representations, warranties,
covenants or agreements of Sellers contained in this Agreement or the Seller
Documents. In order that Purchaser may have full opportunity to make such
physical, business, accounting and legal review, examination or investigation as
it may reasonably request of the affairs of Sellers, Sellers shall use their
commercially reasonable

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<PAGE>

efforts to cause the officers, employees, consultants, agents, accountants,
attorneys and other representatives of Sellers to cooperate fully with such
representatives in connection with such review and examination. Sellers shall
promptly deliver to Purchaser such copies of all pleadings, motions, notices,
statements, schedules, applications, reports and other papers filed by Sellers
in the Chapter 11 Case. Sellers shall promptly provide to Purchaser all
documents and materials relating to the proposed sale of the Purchased Assets,
or any portion thereof, and otherwise cooperate with Purchaser, to the extent
reasonably necessary in connection with Purchaser's preparation for or
participation in any part of the Chapter 11 Case in which Purchaser's
participation is necessary, required or reasonably appropriate. Sellers shall
promptly deliver to Purchaser all pleadings, motions, notices, statements,
schedules, applications, reports and other papers filed in any other judicial or
administrative proceeding as Purchaser may reasonably request.

     8.2 Permitted Sellers. To the extent any Permitted Seller assigns,
licenses, or sublicenses the rights to sell Marketed Products, Lifecycle
Products, or New Products, such Permitted Seller must notify Sellers in writing
no later than three (3) Business Days after such assignment, license, or
sublicense of the identity of the new Permitted Seller and provide Sellers with
a copy of such assignment, license, or sublicense agreement.

     8.3 Conduct of the Business Pending the Closing.

          (a) Except as otherwise expressly contemplated by this Agreement
(including the prosecution of the Chapter 11 Case) or with the prior written
consent of Purchaser, Sellers shall, and shall cause their Subsidiaries to, with
respect to the Business only:

               (i) except as set forth in Schedule 8.3, conduct the Business
     only in the Ordinary Course of Business as debtors in possession;

               (ii) use their commercially reasonable efforts, as debtors in
     possession, to (A) preserve their present business operations, organization
     (including employees) and goodwill of Sellers and (B) preserve the present
     relationships with Persons having business dealings with Sellers (including
     without limitation customers and suppliers);

               (iii) maintain (A) all of the Purchased Assets and Licensed
     Assets in their current condition, ordinary wear and tear excepted and (B)
     insurance upon all of the Purchased Assets and Licensed Assets in such
     amounts and of such kinds comparable to that in effect on the date of this
     Agreement;

               (iv) (A) maintain the books, accounts and records of Sellers in
     the Ordinary Course of Business, (B) continue to pay, with respect to the
     Purchased Contracts, post-petition accounts payable when due and without
     discounting or accelerating payment of such accounts, and (C) subject to
     existing defaults and future payment defaults, comply with all obligations
     under the Purchased Contracts;

               (v) comply in all material respects with Applicable Laws; and

               (vi) not take any action which would adversely affect the ability
     of the parties to consummate the transactions contemplated by this
     Agreement.

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<PAGE>

          (b) Except as otherwise expressly contemplated by this Agreement
(including the prosecution of the Chapter 11 Case) or with the prior written
consent of Purchaser, Sellers shall not, and shall not permit their Subsidiaries
to, with respect to the Business only:

               (i) with respect to the Employees set forth in Schedule 9.1,
     enter into any non-competition or similar agreement to which Sellers or any
     of their Subsidiaries is a party;

               (ii) make or rescind any election relating to Taxes or settle or
     compromise any claim, action, suit, litigation, proceeding, arbitration,
     investigation, audit or controversy relating to Taxes to the extent that
     such election, settlement or compromise would have any material
     post-Closing effect that would be binding on Purchaser for taxable periods
     (or portions thereof) beginning on or after the Closing Date;

               (iii) sell, assign, license, transfer, convey, lease or otherwise
     dispose of any of the Purchased Assets (except for fair consideration in
     the Ordinary Course of Business) of Sellers;

               (iv) with respect to the Employees set forth in Schedule 9.1,
     enter into any labor or collective bargaining agreement or, through
     negotiation or otherwise, make any commitment or incur any liability to any
     labor organization;

               (v) except as set forth in Schedule 8.3, introduce any material
     change with respect to the operation of the Business, including any
     material change in the types, nature, composition (except as required by
     the FDA) or quality of the Products or services, or make any change in
     Product specifications or prices or terms of distributions of such
     Products;

               (vi) enter into any Contract, understanding or commitment that
     restrains, restricts, limits or impedes the ability of the Business, or the
     ability of Purchaser, to compete with or conduct any business or line of
     business in any geographic area;

               (vii) terminate, amend, restate, supplement or waive any rights
     under any Purchased Contract or Intellectual Property License; or

               (viii) agree to do anything prohibited by this Section 8.3 or
     anything which would make any of the representations and warranties of
     Sellers in this Agreement untrue or incorrect in any material respect.

     8.4 Development of Darvocet-N XR and Lynxorb. Upon the entry of the Bidding
Procedures Order and prior to the Closing Date, upon Purchaser's written notice
to Sellers, Sellers shall continue to develop the Darvocet-N XR Product and the
Lynxorb Product in accordance with a development plan mutually agreed upon by
Sellers and Purchaser, with such costs and expenses of development to be funded
by Purchaser (the "Development Costs") up to $1,000,000; provided, that nothing
contained herein shall be deemed an affirmative obligation, absent Purchaser's
written notice, to develop the Darvocet-N XR Product or the Lynxorb Product in
the Ordinary Course of Business.

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     8.5 Rejection of Contracts. Except as set forth in Schedule 8.5, Sellers
shall not seek to have any Contract related to the Business rejected in the
Chapter 11 Case until after the Closing Date.

     8.6 Consents. Sellers and Purchaser shall use (and shall cause each of
their Subsidiaries to use) their commercially reasonable efforts, and Purchaser
shall cooperate with Sellers, to obtain at the earliest practicable date all
consents and approvals required to consummate the transactions contemplated by
this Agreement, including, without limitation, the consents and approvals
referred to in Section 5.4(b) hereof.

     8.7 Regulatory Approvals.

          (a) Each of Purchaser and Sellers shall (i) make or cause to be made
all filings required of each of them or any of their respective Subsidiaries or
Affiliates under the HSR Act or other Antitrust Laws with respect to the
transactions contemplated hereby as promptly as practicable and, in any event,
within five (5) Business Days after approval of the Bidding Procedures by the
Bankruptcy Court in the case of all filings required under the HSR Act and
within ten (10) Business Days in the case of all other filings required by other
Antitrust Laws, (ii) comply at the earliest practicable date with any request
under the HSR Act or other Antitrust Laws for additional information, documents,
or other materials received by each of them or any of their respective
Subsidiaries from the Federal Trade Commission (the "FTC"), the Antitrust
Division of the United States Department of Justice (the "Antitrust Division")
or any other Governmental Body in respect of such filings or such transactions,
and (iii) cooperate with each other in connection with any such filing
(including, to the extent permitted by Applicable Law, and at Purchaser's cost
providing copies of all such documents to the non-filing parties prior to filing
and considering all reasonable additions, deletions or changes suggested in
connection therewith) and in connection with resolving any investigation or
other inquiry of any of the FTC, the Antitrust Division or other Governmental
Body under any Antitrust Laws with respect to any such filing or any such
transaction. Each such party shall use commercially reasonable efforts to
furnish to each other all information required for any application or other
filing to be made pursuant to any applicable law in connection with the
transactions contemplated by this Agreement. Each such party shall promptly
inform the other parties hereto of any oral communication with, and provide
copies of written communications with, any Governmental Body regarding any such
filings or any such transaction. No party hereto shall independently participate
in any formal meeting with any Governmental Body in respect of any such filings,
investigation, or other inquiry without giving the other parties hereto prior
notice of the meeting and, to the extent permitted by such Governmental Body,
the opportunity to attend and/or participate. Subject to applicable law, the
parties hereto will consult and cooperate with one another in connection with
any analyses, appearances, presentations, memoranda, briefs, arguments, opinions
and proposals made or submitted by or on behalf of any party hereto relating to
proceedings under the HSR Act or other Antitrust Laws. Sellers and Purchaser
may, as each deems advisable and necessary, reasonably designate any
competitively sensitive material provided to the other under this Section 8.7 as
"outside counsel only." Such materials and the information contained therein
shall be given only to the outside legal counsel of the recipient and will not
be disclosed by such outside counsel to employees, officers, or directors of the
recipient, unless express written permission is obtained in advance from the
source of the materials (Sellers or Purchaser, as the case may be).
Notwithstanding anything to the contrary

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provided herein, none of Sellers, Purchaser nor any of their respective
Affiliates shall be required (i) to hold separate (including by trust or
otherwise) or divest any of its businesses, product lines or assets, or any of
the Purchased Assets, (ii) to agree to any limitation on the operation or
conduct of the Business, or (iii) to waive any of the conditions to this
Agreement set forth in Section 10.1.

          (b) Each of Purchaser and Sellers shall use commercially reasonable
efforts to resolve such objections, if any, as may be asserted by any
Governmental Body with respect to the transactions contemplated by this
Agreement under the HSR Act, the Sherman Act, as amended, the Clayton Act, as
amended, the Federal Trade Commission Act, as amended, and any other United
States federal or state or foreign statutes, rules, regulations, orders,
decrees, administrative or judicial doctrines or other laws that are designed to
prohibit, restrict or regulate actions having the purpose or effect of
monopolization or restraint of trade (collectively, the "Antitrust Laws"). In
connection therewith, if any Legal Proceeding is instituted (or threatened to be
instituted) challenging any transaction contemplated by this Agreement is in
violation of any Antitrust Law, Sellers shall use reasonable best efforts, and
Purchaser shall cooperate with Sellers, to contest and resist any such Legal
Proceeding, and to have vacated, lifted, reversed, or overturned any decree,
judgment, injunction or other order whether temporary, preliminary or permanent,
that is in effect and that prohibits, prevents, or restricts consummation of the
transactions contemplated by this Agreement, including by pursuing all available
avenues of administrative and judicial appeal and all available legislative
action, unless, by mutual agreement, Purchaser and Sellers decide that
litigation is not in their respective best interests. Each of Purchaser and
Sellers shall use commercially reasonable efforts to take such action as may be
required to cause the expiration of the notice periods under the HSR Act or
other Antitrust Laws with respect to such transactions as promptly as possible
after the execution of this Agreement. Notwithstanding anything to the contrary
provided herein, none of Sellers, Purchaser nor any of their respective
Affiliates shall be required (i) to hold separate (including by trust or
otherwise) or divest any of its businesses, product lines or assets, or any of
the Purchased Assets, (ii) to agree to any limitation on the operation or
conduct of the Business, or (iii) to waive any of the conditions to this
Agreement set forth in Section 10.1.

          (c) All filings fees related to this Agreement incurred in connection
with the HSR Act or other Antitrust Laws shall be borne by the parties in
accordance with their respective legal obligations.

     8.8 Further Assurances. Subject to Section 8.7, each of Sellers and
Purchaser shall use its commercially reasonable efforts to (i) take all actions
reasonably necessary or appropriate to consummate the transactions contemplated
by this Agreement including actively pursuing and securing the financing as set
forth in the Commitment Letters and (ii) cause the fulfillment at the earliest
practicable date of all of the conditions to their respective obligations to
consummate the transactions contemplated by this Agreement. Without limiting the
foregoing, Purchaser or Sellers, as applicable, shall cooperate in transferring
Excluded Assets to Sellers or Purchased Assets (including assets of Sellers
intended to be Purchased Assets) to Purchaser, including turning over any
payments received by the other party, and assisting in the collection of any
Excluded Assets. Sellers shall take all necessary actions to enforce all rights
of Sellers with respect to employees, consultants and agents of Sellers and
their Subsidiaries, who are contributors to the science of patentable inventions
of the Darvocet-N XR Product, the Lynxorb

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Product, the Darvocet-N Suspension Product, and the New Products to effectuate
the transactions contemplated herein.

     8.9 Non-Competition; Non-Solicitation; Confidentiality.

          (a) Except with respect to Sellers' manufacturing Products for
Purchaser pursuant to the Manufacturing Agreement or as otherwise provided for
in Section 3.3, for a period from the Closing Date until the seventh (7th)
anniversary of the Closing Date, Sellers shall not and shall cause their
Subsidiaries not to directly or indirectly, own, manage, operate, control or
participate in the ownership, management, operation or control of any business,
whether in corporate, proprietorship or partnership form or otherwise, engaged
in the marketing, promoting, distributing and selling of pharmaceutical products
competitive with any of the Products (a "Restricted Business") in the Territory;
provided, however, that the restrictions contained in this Section 8.9(a) shall
not restrict the acquisition by Sellers, directly or indirectly, of less than 2%
of the outstanding capital stock of any publicly traded company engaged in a
Restricted Business; provided, further, however, that, except as otherwise
provided for in Section 3.3, nothing contained herein shall preclude Sellers or
their Affiliates from developing or manufacturing products for third parties.

          (b) For a period of one (1) year from the Closing Date, Sellers shall
not and shall cause their Subsidiaries not to: (i) cause, solicit, induce or
encourage any employees of Sellers who are or become employees of Purchaser or
its Affiliates to leave such employment or hire, employ or otherwise engage any
such individual; or (ii) cause, induce or encourage any material client,
customer, supplier, or licensor of the Business (including any existing customer
of Sellers and any Person that becomes a client or customer of the Business
after the Closing) or any other Person who has a material business relationship
with the Business, to terminate or modify any such relationship; provided that
the foregoing shall not apply to general advertisements in newspapers,
newsletters, magazines, commercials, billboards, or other media outlets.

          (c) For the period commencing on the date hereof and continuing until
one (1) year from the Closing Date, Purchaser shall not and shall cause its
Affiliates not to: (i) cause, solicit, induce or encourage any employees of
Sellers or their Affiliates, except as set forth in Schedule 9.1, to become
employees of Purchaser or its Affiliates to leave such employment or hire,
employ or otherwise engage any such individual without the prior written consent
of Sellers; or (ii) cause, induce or encourage any material actual client,
customer, supplier, or licensor of Sellers or their Affiliates, except as set
forth in Schedule 9.1 (including any existing customer of Sellers, their
Affiliates, or the Business and any Person that becomes a client or customer of
the Business after the Closing) or any other Person who has a material business
relationship with the Sellers, their Affiliates or the Business, to terminate or
modify any such actual or prospective relationship.

          (d) The confidentiality agreement between Purchaser and Parent dated
November 12, 2004 (the "Confidentiality Agreement") shall remain in effect and
terminate upon the earlier to occur of the Closing and as otherwise provided in
the Confidentiality Agreement. From and after the Closing Date, none of Sellers
or Purchaser shall, and each shall cause their respective Affiliates, officers
and directors (collectively, with Sellers or Purchaser, as applicable,

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a "Receiving Party") not to, directly or indirectly, without the prior written
consent of the other (the "Disclosing Party"), disclose any Confidential
Information (as defined below) of the Disclosing Party to any Person, except to
a Receiving Party's or its Affiliates' employees or representatives who need to
know such information for any reason contemplated by this Agreement (and then
only to the extent that such Persons are under an obligation to maintain the
confidentiality of the Confidential Information), or use any Confidential
Information of the Disclosing Party for any reason other than contemplated by
this Agreement unless such Receiving Party has (i) consulted with the Disclosing
Party and obtained the Disclosing Party's prior written consent or (ii) been
advised by counsel that disclosure is required to be made under Applicable Law,
legal process, subpoena, litigation, discovery requests or demands from a
Governmental Body or other legal compulsion, or the requirements of a national
securities exchange or another similar regulatory body. In the event that the
Receiving Party is required by subpoena, civil investigative demand,
interrogatories, requests for information, or other similar process, as provided
for in the preceding sentence, to disclose any Confidential Information, the
Receiving Party shall provide the Disclosing Party with prompt written notice of
such demands so that the Disclosing Party may seek an appropriate protective
order; provided, however, to the extent that the Disclosing Party does not seek
a protective order or it is denied a protective order, such disclosure of
Confidential Information by the Receiving Party shall not constitute a breach of
this Agreement. Notwithstanding the foregoing, Sellers shall not make any
filings with the Bankruptcy Court or otherwise permit any filings to be made
with respect to any Confidential Information of Purchaser without the reasonable
prior written consent of Purchaser, and Sellers further agree that any such
filings shall be made under seal pursuant to section 107(b) of the Bankruptcy
Code and Bankruptcy Rule 9018 to the extent reasonably requested by Purchaser.
For purposes of this Section 8.9(d), "Confidential Information" means any
confidential information with respect to the Business, including, Licensed
Assets, methods of operation, customers, customer lists, Products, prices, fees,
costs, technology, inventions, trade secrets, know how, software, marketing
methods, plans, personnel, suppliers, competitors, markets or other specialized
information or proprietary matters. "Confidential Information" does not include,
and there shall be no obligation hereunder with respect to, information that (i)
is generally available to the public on the date of this Agreement or (ii)
becomes generally available to the public other than as a result of a disclosure
not otherwise permissible hereunder. This Section 8.9 shall not in any way limit
the disclosure of information (x) by Sellers in connection with the prosecution
of the Chapter 11 Case or (y) regarding Sellers to other bidders or potential
bidders, to the extent specifically permitted by this Agreement. Notwithstanding
the generality of the foregoing, Sellers agree that, without Purchaser's prior
written consent, Sellers shall not disclose the identity of Purchaser's
financing sources or the amount or terms of financing proposed to be supplied by
an such source, except as otherwise required by Applicable Law or by the
Bankruptcy Court with respect to filings to be made with the Bankruptcy Court in
connection with this Agreement.

          (e) The covenants and undertakings contained in this Section 8.9
relate to matters which are of a special, unique and extraordinary character and
a violation of any of the terms of this Section 8.9 will cause irreparable
injury to the parties, the amount of which will be impossible to estimate or
determine and which cannot be adequately compensated. Therefore, Purchaser will
be entitled to an injunction, restraining order or other equitable relief from
any court of competent jurisdiction in the event of any breach of this Section
8.9. The rights and remedies provided by this Section 8.9 are cumulative and in
addition to any other rights and

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remedies which Purchaser may have hereunder or at law or in equity. In the event
that Purchaser were to seek damages for any breach of this Section 8.9, the
portion of the Purchase Price which is allocated by the parties to the foregoing
covenant shall not be considered a measure of or limit on such damages.

          (f) The parties hereto agree that, if any court of competent
jurisdiction in a final nonappealable judgment determines that a specified time
period, a specified geographical area, a specified business limitation or any
other relevant feature of this Section 8.9 is unreasonable, arbitrary or against
public policy, then a lesser time period, geographical area, business limitation
or other relevant feature which is determined to be reasonable, not arbitrary
and not against public policy may be enforced against the applicable party.

     8.10 Preservation of Records. Sellers and Purchaser agree that each of them
shall preserve and keep the records held by it or their Affiliates relating to
the Business for a period of seven (7) years from the Closing Date and shall
make such records and personnel available to the other as may be reasonably
required by such party in connection with, among other things, any insurance
claims by, legal proceedings against or governmental investigations of Sellers
or Purchaser or any of their Affiliates or in order to enable Sellers or
Purchaser to comply with their respective obligations under this Agreement and
each other agreement, document or instrument contemplated hereby or thereby. To
the extent that any party provides the other with records relating to the
Business, such party providing the files shall have the right to duplicate and
maintain copies of such files. In the event Sellers or Purchaser wishes to
destroy such records before or after that time, such party shall first give
ninety (90) days prior written notice to the other and such other party shall
have the right at its option and expense, upon prior written notice given to
such party within such ninety (90) day period, to take possession of the records
within one hundred and eighty (180) days after the date of such notice.

     8.11 Publicity. Neither Sellers nor Purchaser shall issue any press release
or public announcement concerning this Agreement or the transactions
contemplated hereby without obtaining the prior written approval of the other
party hereto, which approval will not be unreasonably withheld or delayed,
unless, in the sole judgment of Purchaser or Sellers, disclosure is otherwise
required by Applicable Law or by the Bankruptcy Court with respect to filings to
be made with the Bankruptcy Court in connection with this Agreement or by the
applicable rules of any stock exchange on which Purchaser or Sellers lists
securities, provided that the party intending to make such release shall use
commercially reasonable efforts consistent with such Applicable Law or
Bankruptcy Court requirement to consult with the other party with respect to the
text thereof.

     8.12 aaiPharma Name. From the earlier to occur of (i) one (1) year
following the Closing Date or (ii) until exhaustion of packaging and promotional
materials existing as of the Closing Date ("AAI Packaging"), Purchaser shall
have the right to use, in connection with the AAI Packaging, the name
"aaiPharma" or similar names or any service marks, trademarks, trade names,
identifying symbols, logos, emblems or signs containing or comprising the
foregoing, only to the extent that such right is reasonably necessary or
required for the limited use of the AAI Packaging.

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     8.13 Cooperation with Financing. In order to assist with obtaining
Purchaser's acquisition financing in connection with this Agreement, Sellers
shall, and shall cause their Subsidiaries to, provide such reasonable assistance
and cooperation as Purchaser and its Affiliates may reasonably request.

     8.14 Returns, Rebates and Chargebacks.

          (a) (i) Sellers shall be financially responsible for returned Marketed
Products sold by Sellers prior to the Closing Date and Purchaser shall be
financially responsible for returned Marketed Products sold by Purchaser on or
after the Closing Date, provided that Sellers and Purchaser shall be financially
responsible for their own allocated percentage of Split Lots of returned
Marketed Products that will be set forth on a schedule of Split Lots to be
provided by Sellers within ten (10) Business Days after the Closing Date;
provided, however, that Sellers' financial obligation for such returns shall
terminate two hundred seventy (270) days after the Closing Date. Such allocated
percentage of a Split Lot that Purchaser shall be responsible for under this
Section 8.14(a)(i) shall be equal to the percentage of such Split Lot located at
SPS Cord on the Closing Date and such allocated percentage of a Split Lot that
Sellers shall be responsible for under this Section 8.14(a)(i) shall equal the
percentage of such Split Lot not located at SPS Cord on the Closing Date.

               (ii) As of the Closing, Purchaser and Sellers will use
     commercially reasonable efforts in requesting that customers direct all
     returned Marketed Products to Purchaser; provided, however, that except as
     set forth on Schedule 8.14(a)(ii), returned Marketed Products received by
     Purchaser or Sellers after the Closing Date will be handled by such party
     at its respective returns handling facility. Neither Purchaser nor Sellers
     shall issue credits or make any cash payments for returned Marketed
     Products for which the other party is financially responsible as set forth
     in Section 8.14(a)(i) above; provided, however, that such party shall
     destroy such returned Marketed Product and invoice the other party for the
     reasonable cost of destruction. Each such invoice shall set forth
     information as shall be necessary to support the invoice. Sellers and
     Purchaser shall, within thirty (30) days of such party's receipt of
     invoice, pay the other party for the full invoiced amount. Notwithstanding
     anything else contained herein, if either Purchaser or Sellers issue
     financial credit or other reimbursement for returned Marketed Products and
     related administrative fees for which the other party was financially
     responsible as set forth in this Section 8.14(a), such party shall invoice
     the other party for such amount setting forth information as shall be
     reasonably necessary to support the invoice. Purchaser and Sellers shall,
     within thirty (30) days of Purchaser's or Sellers' receipt of invoice, pay
     the other party for the full invoiced amount.

               (iii) Neither Purchaser nor Sellers shall encourage Marketed
     Product returns or accept Marketed Product returns outside of its normal
     course of business without the prior written approval of the other party.

          (b) Sellers shall be financially responsible for all rebates pursuant
to any rebate programs, including government rebate programs, with respect to
claims for the Marketed Products dispensed (the dispense date contained in any
report from a rebate program shall be used for purposes of determining the date
of such rebate) on or before thirty (30) days after the

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Closing Date; provided, however, that Sellers' financial obligation for such
rebates shall terminate one-hundred eighty (180) days after the Closing Date
(the "Rebates Termination Date"). Purchaser shall assume financial
responsibility for all rebates pursuant to any such rebate programs with respect
to claims for the Marketed Products dispensed after the Rebates Termination
Date. Purchaser and Sellers acknowledge that government rebates are billed on a
calendar quarter basis and to the extent that the periods set forth in this
Section 8.14(b) do not end on a calendar quarter, the Purchaser and Seller shall
make payments for such fractional periods of any applicable quarter on a
pro-rata basis based on the number of days for which such party is responsible
for rebates in the applicable quarter. Purchaser acknowledges that Sellers will
require certain information from Purchaser in order to calculate the Medicaid
rebate for Marketed Products bearing Sellers' NDC number. Accordingly, Purchaser
agrees that, from and after the Closing Date until the date which is one (1)
calendar year after the expiration date of the last lot of Marketed Products
produced with Sellers' NDC number, Purchaser will provide to Sellers,
concurrently with its timely delivery of related information to the Centers for
Medicare and Medicaid Services (or any successor agency), the following
information: (a) the "best price" (as defined under the Social Security Act, 42
U.S.C. Section 1396r-8(c)(l)(C)) for each Marketed Product identified by NDC
number, (b) on the twentieth (20th) day after the end of each calendar quarter
during such one (1) year period, all information reasonably necessary for
Sellers to calculate the "average manufacturer price" (as defined under the
Social Security Act, 42 U.S.C. Sections 1396r-8(k)(l)) for each Marketed Product
identified by NDC number, and (c) any additional data or other information
related to such Medicaid issues reasonably requested by Sellers.

          (c) Sellers shall be financially responsible for all chargeback claims
and related administrative service fees for the Marketed Products with a
chargeback invoice dated (i.e., the date of sale from the wholesaler to the
wholesaler customer) on or before forty-five (45) days after the Closing Date;
provided, however, that Sellers' maximum financial obligation for chargeback
claims and related administrative service fees for the Marketed Products shall
terminate one-hundred eighty (180) days after the Closing Date (the "Chargeback
Termination Date"). Purchaser shall be financially responsible for all
chargeback claims and related administrative service fees for the Marketed
Products with a chargeback invoice dated after the Chargeback Termination Date.
If either Purchaser or Sellers issues financial credit or other reimbursement
for chargeback claims and related administrative fees for which the other party
was financially responsible as set forth in this Section 8.14(c), such party
shall invoice the other party for such amount setting forth information as shall
be reasonably necessary to support the invoice. Purchaser and Sellers shall,
within thirty (30) days of Purchaser's or Sellers' receipt of invoice, pay the
other party for the full invoiced amount.

          (d) After the Closing Date, the Purchaser and Sellers shall use
commercially reasonable efforts and cooperate in good faith to notify the
wholesale trade customers that Purchaser will begin marketing the Marketed
Products, which notification shall include letters or other communication as
Purchaser and Sellers may mutually agree.

          (e) In the event that Purchaser increases the published Wholesaler
Acquisition Cost ("WAC") of any of the Marketed Products prior to the last to
expire of the Rebates Termination Date or the Chargeback Termination Date,
Purchaser shall (i) promptly notify Sellers of such increase and (ii) reimburse
Sellers the increase in amounts associated with

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returns, rebates or chargebacks as a result of such increase in WAC. Purchaser
and Sellers acknowledge that a percentage increase in WAC may result in a
greater percentage increase in rebates, in which case Sellers would invoice
Purchaser for the full increase in the rebate. Sellers shall invoice Purchaser
on a monthly basis for amounts due pursuant to this Section 8.14(e) and
Purchaser shall pay such invoices within thirty (30) days after receipt of same.

     8.15 Adverse Experience Reporting and Product Complaints. Sellers shall
promptly submit to Purchaser all adverse drug experience information and product
complaints brought to the attention of Sellers in writing following the Closing
in respect of any of the Products, as well as any material events and matters
concerning or affecting the safety or efficacy of any of the Products. Without
limiting the foregoing, Sellers shall notify Purchaser of any adverse or
unexpected event brought to the attention of Sellers in writing following the
Closing in respect of any of the Products within three (3) Business Days from
the date Sellers receive written notice of such event.

     8.16 Recalls. Purchaser shall be solely responsible and liable for
conducting all voluntary recalls, stop sales, field alerts, market withdrawals
or other related actions (collectively "Recalls") of units of any Products after
the Closing Date relating to Products sold by or on behalf of Sellers prior to
the Closing Date; provided, however, that, subject to Purchaser's compliance
with this Section 8.16, Sellers shall reimburse Purchaser for all of its
reasonable out-of-pocket costs and expenses, including notification, shipping
and handling charges and amounts refunded or credited to customers incurred in
respect of any Recalls relating to the Products sold by or on behalf of Sellers
prior to the Closing Date and deemed necessary by Purchaser in Purchaser's
commercially reasonable judgment. Purchaser shall reasonably consult with
Sellers and take into consideration Sellers' reasonable recommendations
regarding such Recalls; provided, that Purchaser shall not be required to
consult with Sellers in advance to the extent circumstances preclude prior
consultation. In addition, Purchaser shall use commercially reasonable efforts
to mitigate the costs and expenses associated with any such Recall.

     8.17 Inventory. Sellers shall deliver the Inventory to Purchaser FOB
Sellers' third party distribution center. Sellers shall invoice Purchaser for
reasonable storage fees with respect to Inventory not picked up by Purchaser
within ten (10) Business Days after the Closing Date. Purchaser shall pay any
such invoiced amounts within thirty (30) days of its receipt of invoice.

     8.18 Financial Statements. At Purchaser's cost (and with Purchaser making
direct arrangements with certified public accountants), Sellers shall use their
commercially reasonable efforts to furnish Purchaser and its representatives as
soon as practicable, but no later than sixty (60) days after the Closing Date,
audited balance sheets of the Purchased Assets, Licensed Assets and Assumed
Liabilities as at December 31, 2002, 2003 and 2004 and the audited statements
of gross revenue, net revenues and direct costs for the three (3) years ended
December 31, 2004. No later than September 30, 2005, Sellers shall furnish
Purchaser and its representatives with a balance sheet of the Purchased Assets,
Licensed Assets and Assumed Liabilities as at June 30, 2005 and the statement of
gross revenues, net revenues and direct costs of the Business for the six-month
period ended June 30, 2004. At Purchaser's expense, Sellers shall also make
reasonable efforts to furnish Purchaser with such other financial, business and
operating data of the Business as may be required or reasonably requested by
Purchaser for inclusion in, or in connection with, any private placement
memoranda or filings with the U.S. Securities and

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Exchange Commission and registration statement (including, without limitation,
any prospectus supplement) of Purchaser under the Securities Act of 1933, as
amended (the "Securities Act"), including using commercially reasonable efforts
to furnish Purchaser, with financial information of the Business for any period
ending on or before the Closing Date that complies with any requirements of the
staff of the SEC applicable to the balance sheets and statements of gross
revenue, net revenues and direct costs described above and using reasonable
commercial efforts to cause Sellers' certified public accountants to provide
their opinion, consents for the inclusion thereof in any such registration
statement and comfort letters that are customary for registration statements or
private placement memoranda.

     8.19 Differentiation of Products. Not later than three (3) months following
the Closing, Purchaser shall use commercially reasonable efforts to ensure that
Marketed Products manufactured, finished or sold by, or on behalf of, Purchaser
bear an NDC code different than that used by the Sellers for the Marketed
Products.

     8.20 Resale Certificates. Purchaser shall use commercially reasonable
efforts to deliver to Sellers at the Closing resale certificates with respect to
the Inventory, in form and substance mutually acceptable to Purchaser and
Sellers, but in no event shall the failure to deliver such resale certificates
delay the Closing or the delivery of such resale certificates be deemed a
condition to the Closing.

     8.21 Enforcement of Rights. Sellers shall enforce all rights of Sellers
under non-disclosure or confidentiality, non-compete, or non-solicitation
agreements (collectively, the "Restrictive Agreements") with employees and
agents of Sellers or with third parties to the extent relating to the Business,
the Purchased Assets (or any portion thereof) or the Licensed Assets (or any
portion thereof) and Sellers shall aggressively pursue all litigation in
connection with any breach of such Restrictive Agreements. If Sellers fail to
aggressively pursue any such litigation, then, at Purchaser's option, Purchaser
may send written notice to Sellers indicating Purchaser's desire to take over
such litigation, and Sellers shall, upon receipt of such written notice,
promptly assign their right to pursue such litigation to Purchaser and Purchaser
shall have the right pursue such litigation, at Purchaser's cost.

     8.22 Laboratory Notebooks. Within a commercially reasonable time after the
Closing Date, Sellers shall, at Purchaser's expense, create and deliver copies
of the Notebooks to Purchaser, provided that prior to the delivery of copies of
the Notebooks relating to the Licensed Assets, Purchaser and Sellers shall enter
into a mutually acceptable confidentiality/non-disclosure or similar agreement
protecting the confidentiality of, and any applicable privilege or protection
in, the information contained in such Notebooks.

     8.23 Darvocet-N XR IDM. Prior to the Closing Date, Sellers shall update the
Darvocet-N XR IDM to reflect the then-current formulation of the Darvocet-N XR
Product to the extent the relevant formulation exists or is available.

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                                   ARTICLE IX

                                    EMPLOYEES

     9.1 Employment.

          (a) Except as otherwise provided herein, at any time immediately prior
to or after the Closing, Purchaser shall be permitted to offer employment to
those employees listed on Schedule 9.1. Such individuals who accept such offer
are referred to herein as the "Transferred Employees." Subject to Applicable
Laws, Purchaser shall have the right to dismiss any or all Transferred Employees
at any time, with or without cause, and to change the terms and conditions of
their employment (including compensation and employee benefits provided to
them).

          (b) To the extent permitted by Applicable Law, from time to time
following the Closing, Sellers shall, or shall cause their Subsidiaries to, make
available to Purchaser such non-confidential data in personnel records of
Transferred Employees as is reasonably necessary for Purchaser to transition
such employees into Purchaser's records.

     9.2 Indemnification. Sellers shall indemnify and hold Purchaser and its
Affiliates harmless with respect to any Transferred Employee from (i) any
employment- related liability with respect to employment on or prior to the date
any such Transferred Employee was hired by Purchaser and (ii) any liability
under WARN.

                                    ARTICLE X

                              CONDITIONS TO CLOSING

     10.1 Conditions Precedent to Obligations of Purchaser. The obligation of
Purchaser to consummate the transactions contemplated by this Agreement is
subject to the fulfillment, on or prior to the Closing Date, of each of the
following conditions (any or all of which may be waived by Purchaser in whole or
in part to the extent permitted by Applicable Law):

          (a) the representations and warranties of Sellers set forth in this
Agreement qualified as to materiality shall be true and correct, and those not
so qualified shall be true and correct in all material respects, as of the date
of this Agreement and as of the Closing as though made at and as of the Closing,
except to the extent such representations and warranties expressly relate to an
earlier date (in which case such representations and warranties qualified as to
materiality shall be true and correct, and those not so qualified shall be true
and correct in all material respects, on and as of such earlier date) and
Purchaser shall have received a certificate signed by an authorized officer of
Sellers (in form and substance reasonably satisfactory to Purchaser), dated the
Closing Date, to such effect;

          (b) Sellers shall have performed and complied in all material respects
with all obligations and agreements required in this Agreement to be performed
or complied with by it prior to the Closing Date, and Purchaser shall have
received a certificate signed by an authorized officer of Sellers (in form and
substance reasonably satisfactory to Purchaser), dated the Closing Date, to such
effect;

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          (c) there shall not have been or occurred any event, change,
occurrence or circumstance that has had or which could reasonably be expected to
have a Material Adverse Effect since the Balance Sheet Date, provided that if
there is an oral indication by the FDA that a factorial design study (being a
study in which the Darvocet-N XR Product is required to be compared against one
or more of its ingredients alone) may or will be required for FDA approval of
the Darvocet-N XR Product, Purchaser shall not be obligated to consummate the
transactions contemplated by this Agreement unless there is a subsequent written
indication by the FDA that no such factorial design study is required, and if
there is a written indication by the FDA that such factorial design study is
required, then such written indication shall be a Material Adverse Effect; and

          (d) Purchaser shall have received the financing set forth in the
Commitment Letters, which condition shall be deemed satisfied if Purchaser does
not provide written notice to Sellers on or prior to three (3) Business Days
before the Bankruptcy Court's hearing with respect to the Bidding Procedures
that such condition has not been satisfied.

     10.2 Conditions Precedent to Obligations of Sellers. The obligations of
Sellers to consummate the transactions contemplated by this Agreement are
subject to the fulfillment, prior to or on the Closing Date, of each of the
following conditions (any or all of which may be waived by Sellers in whole or
in part to the extent permitted by applicable law):

          (a) The representations and warranties of Purchaser set forth in this
Agreement qualified as to materiality shall be true and correct, and those not
so qualified shall be true and correct in all material respects, as of the date
of this Agreement and as of the Closing as though made at and as of the Closing,
except to the extent such representations and warranties expressly relate to an
earlier date (in which case such representations and warranties qualified as to
materially shall be true and correct, and those not so qualified shall be true
and correct in all material respects, on and as of such earlier date) and
Sellers shall have received a certificate signed by an authorized officer of
Purchaser (in form and substance reasonably satisfactory to Purchaser), dated
the Closing Date, to such effect;

          (b) Purchaser shall have performed and complied in all material
respects with all obligations and agreements required by this Agreement to be
performed or complied with by Purchaser on or prior to the Closing Date and
Sellers shall have received a certificate signed by an authorized officer of
Purchaser (in form and substance reasonably satisfactory to Sellers), dated the
Closing Date, to such effect; and

          (c) Purchaser shall have paid the Purchase Price in accordance with
Section 3.9.

     10.3 Conditions Precedent to Obligations of Purchaser and Sellers. The
respective obligations of Purchaser and Sellers to consummate the transactions
contemplated by this Agreement are subject to the fulfillment, on or prior to
the Closing Date, of each of the following conditions (any or all of which may
be waived by Purchaser and Sellers in whole or in part to the extent permitted
by Applicable Law):

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          (a) no Legal Proceedings (including any proceeding over which the
Bankruptcy Court has jurisdiction under 28 U.S.C. Section 157(b)) shall have
been instituted or threatened or claim or demand made against Sellers or
Purchaser seeking to restrain or prohibit or to obtain substantial damages with
respect to the consummation of the transactions contemplated hereby, and there
shall not be in effect any Order by a Governmental Body of competent
jurisdiction restraining, enjoining or otherwise prohibiting the consummation of
the transactions contemplated hereby;

          (b) the Bankruptcy Court shall have entered the Bidding Procedures
Order and the Sale Order shall be a Final Order;

          (c) the waiting period under the HSR Act shall have expired or early
termination shall have been granted and Sellers shall have obtained any other
consent, approval, order or authorization of, or registration, declaration or
filing with, any Governmental Body required to be obtained or made in connection
with the execution and delivery of this Agreement or the performance of the
transactions contemplated herein and no Governmental Body shall have instituted,
or announced an intention to institute, any proceeding against Purchaser or
either Seller arising out of or based upon an antitrust, competition or similar
Applicable Law in connection with the transactions contemplated herein:

          (d) each of Sellers on the one hand and Purchaser on the other hand
shall have executed and delivered to each other the (i) Services Agreement, (ii)
the Manufacturing Agreement and (iii) the Odyssey Co-Development Agreement; and

          (e) Sellers shall have obtained those consents, waivers and approvals
referred to Schedule 10.3(e) hereof in a form satisfactory to Purchaser.

     10.4 Frustration of Closing Conditions. Neither Sellers nor Purchaser may
rely on the failure of any condition set forth in Section 10.1, 10.2, 10.3, or,
as the case may be, if such failure was caused by such party's failure to comply
with any provision of this Agreement.

                                   ARTICLE XI

                                 INDEMNIFICATION

     11.1 Survival of Representations and Warranties. The representations and
warranties of the parties contained in Articles V and VI of this Agreement shall
survive the Closing through and including twelve (12) months following the
Closing Date (the "Survival Period"); provided, however, that any obligations to
indemnify and hold harmless shall not terminate with respect to any Losses as to
which the Person to be indemnified shall have given notice (stating in
reasonable detail the basis of the claim for indemnification) to the
indemnifying party in accordance with Section 13.3(a) before the termination of
the Survival Period.

     11.2 Indemnification.

          (a) Subject to Section 11.4 hereof, Sellers hereby agree to indemnify
and hold Purchaser and its directors, officers, employees, Affiliates,
stockholders, agents, attorneys,

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representatives, successors and assigns (collectively, the "Purchaser
Indemnified Parties") harmless from and against:

               (i) any and all losses, liabilities, obligations, damages, costs
     and expenses (collectively, "Losses") based upon, attributable to or
     resulting from the failure of any representation or warranty of Sellers set
     forth in this Agreement or in any Sellers Document, to be true and correct
     in all respects at the date hereof and at the Closing Date (except where
     Sellers representations and warranties are given as of any other applicable
     date in which case such representation and warranty shall be correct as of
     such date);

               (ii) any and all Losses based upon, attributable to or resulting
     from the breach of any covenant or other agreement on the part of Sellers
     under this Agreement or any Sellers Document;

               (iii) any and all Losses arising out of, based upon or relating
     to any Excluded Asset or any Excluded Liability;

               (iv) any recall, warranty claim, product liability claim or other
     claim which arises from or relates to any Products sold by or on behalf of
     Sellers prior to the Closing Date;

               (v) any amounts owed by Sellers to Purchaser pursuant to Section
     8.14; and

               (vi) any and all notices, actions, suits, proceedings, claims,
     demands, assessments, judgments, costs, penalties and expenses, including
     reasonable attorneys' and other professionals' fees and disbursements
     (collectively, "Expenses") incident to any and all Losses with respect to
     which indemnification is provided hereunder.

          (b) Subject to Section 11.4, Purchaser hereby agrees to indemnify and
hold Sellers and their Affiliates, stockholders, agents, attorneys,
representatives, successors and permitted assigns (collectively, the "Seller
Indemnified Parties") harmless from and against:

               (i) any and all Losses based upon, attributable to or resulting
     from the failure of any representation or warranty of Purchaser set forth
     in this Agreement or any Purchaser Document, to be true and correct at the
     date hereof and at the Closing Date;

               (ii) any and all Losses based upon, attributable to or resulting
     from the breach of any covenant or other agreement on the part of Purchaser
     under this Agreement or any Purchaser Document;

               (iii) any and all Losses arising out of, based upon or relating
     to any Assumed Liability;

               (iv) any and all Losses arising in connection with the conduct
     and operation of Purchaser's business on and after the Closing Date;

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               (v) any recall, warranty claim, product liability claim or other
     claim which arises from or relates to any Products sold by or on behalf of
     Purchaser after the Closing Date;

               (vi) any amounts owed by Purchaser to Sellers pursuant to Section
     8.14; and

               (vii) any and all Expenses incident to any and all Losses with
     respect to which indemnification is provided hereunder.

     11.3 Indemnification Procedures.

          (a) In the event that any Legal Proceedings shall be instituted or
that any claim or demand shall be asserted by any Person in respect of which
payment may be sought under Section 11.2 hereof (regardless of the limitations
set forth in Section 11.4) "Indemnification Claim"), the indemnified party shall
reasonably and promptly cause written notice of the assertion of any
Indemnification Claim of which it has knowledge which is covered by this
indemnity to be forwarded to the indemnifying party. The indemnifying party
shall have the right, at its sole expense, to be represented by counsel of its
choice, which must be reasonably satisfactory to the indemnified party, and to
defend against, negotiate, settle or otherwise deal with any Indemnification
Claim which relates to any Losses indemnified against hereunder; provided that
the indemnifying party shall have acknowledged in writing to the indemnified
party its unqualified obligation to indemnify the indemnified party as provided
hereunder. If the indemnifying party elects to defend against, negotiate, settle
or otherwise deal with any Indemnification Claim which relates to any Losses
indemnified against hereunder, it shall within fifteen (15) Business Days (or
sooner, if the nature of the Indemnification Claim so requires) notify the
indemnified party of its intent to do so. If the indemnifying party elects not
to defend against, negotiate, settle or otherwise deal with any Indemnification
Claim which relates to any Losses indemnified against hereunder, fails to notify
the indemnified party of its election as herein provided or contests its
obligation to indemnify the indemnified party for such Losses under this
Agreement, the indemnified party may defend against, negotiate, settle or
otherwise deal with such Indemnification Claim. If the indemnified party defends
any Indemnification Claim, then the indemnifying party shall reimburse the
indemnified party for the Expenses of defending such Indemnification Claim upon
submission of periodic bills. If the indemnifying party shall assume the defense
of any Indemnification Claim, the indemnified party may participate, at his or
its own expense, in the defense of such Indemnification Claim; provided,
however, that such indemnified party shall be entitled to participate in any
such defense with separate counsel at the expense of the indemnifying party if
(i) so requested by the indemnifying party to participate or (ii) in the
reasonable opinion of counsel to the indemnified party a conflict or potential
conflict exists between the indemnified party and the indemnifying party that
would make such separate representation advisable; and provided, further, that
the indemnifying party shall not be required to pay for more than one such
counsel for all indemnified parties in connection with any Indemnification
Claim. The parties hereto agree to cooperate fully with each other in connection
with the defense, negotiation or settlement of any such Indemnification Claim.
Notwithstanding anything in this Section 11.3 to the contrary, neither the
indemnifying party nor the indemnified party shall, without the written consent
of the other party, settle or compromise any Indemnification Claim or permit a
default or consent to entry of any judgment

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unless the claimant and such party provide to such other party an unqualified
release from all liability in respect of the Indemnification Claim.
Notwithstanding the foregoing, if a settlement offer solely for money damages is
made by the applicable third party claimant, and the indemnifying party notifies
the indemnified party in writing of the indemnifying party's willingness to
accept the settlement offer and, subject to the applicable limitations of
Section 11.4, pay the amount called for by such offer, and the indemnified party
declines to accept such offer, the indemnified party may continue to contest
such Indemnification Claim, free of any participation by the indemnifying party,
and the amount of any ultimate liability with respect to such Indemnification
Claim that the indemnifying party has an obligation to pay hereunder shall be
limited to the lesser of (A) the amount of the settlement offer that the
indemnified party declined to accept plus the Losses of the indemnified party
relating to such Indemnification Claim through the date of its rejection of the
settlement offer or (B) the aggregate Losses of the indemnified party with
respect to such Indemnification Claim. If the indemnifying party makes any
payment on any Indemnification Claim, the indemnifying party shall be
subrogated, to the extent of such payment, to all rights and remedies of the
indemnified party to any insurance benefits or other claims of the indemnified
party with respect to such Indemnification Claim.

          (b) After any final judgment or award shall have been rendered by a
Governmental Body of competent jurisdiction and the expiration of the time in
which to appeal therefrom, or a settlement shall have been consummated, or the
indemnified party and the indemnifying party shall have arrived at a mutually
binding agreement with respect to an Indemnification Claim hereunder, the
indemnified party shall forward to the indemnifying party notice of any sums due
and owing by the indemnifying party pursuant to this Agreement with respect to
such matter and the indemnifying party shall be required to pay all of the sums
so due and owing to the indemnified party by wire transfer of immediately
available funds within ten (10) Business Days after the date of such notice.

          (c) The failure of the indemnified party to give reasonably prompt
notice of any Indemnification Claim shall not release, waive or otherwise affect
the indemnifying party's obligations with respect thereto except to the extent
that the indemnifying party can demonstrate actual loss and prejudice as a
result of such failure.

     11.4 Limitations on Indemnification for Breaches of Representations and
Warranties.

          (a) An indemnifying party shall not have any liability under Section
11.2(a)(i) or Section 11.2(b)(i) hereof unless and until the aggregate amount of
Losses and Expenses to the indemnified parties finally determined to arise
thereunder based upon, attributable to or resulting from the failure of any
representation or warranty to be true and correct (unless such failure is the
result of the indemnifying party's fraud or willful misconduct), other than the
representations and warranties set forth in Sections 5.1, 5.2, 5.8, 5.16 and
6.1, 6.2 and 6.5 hereof, exceeds $1,700,000 (the "Basket"), in which case, only
the Losses in excess of such amount of Loss shall be covered.

          (b) Sellers shall not be required to indemnify any Person for an
aggregate amount of Losses and Expenses above the amount of Sellers' Indemnity
Escrow Fund, which shall be the sole source of payment of such amounts, and
Purchaser shall not be required to

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indemnify any Person for an aggregate amount of Expenses and Losses under
Section 11.2(b)(i) above the amount of Purchaser's Indemnity Escrow Fund.

          (c) For purposes of calculating Losses hereunder with respect to
determining whether the Losses and Expenses exceed $1,700,000 for purposes of
Section 11.4(a), any materiality or material adverse effect qualifications in
the representations, warranties, covenants and agreements shall be ignored.

     11.5 Indemnity Escrows.

          (a) Purchaser's Indemnity Escrow Amount. On the Closing Date,
Purchaser shall pay to the Escrow Agent, in immediately available funds, to the
account designated by the Escrow Agent, the Purchaser's Indemnity Escrow Amount
in accordance with the terms of this Agreement and the Indemnity Escrow
Agreement. Six (6) months after the Closing Date, the Escrow Agent shall release
fifty percent (50%) of (i) the then existing amount of the Purchaser's Indemnity
Escrow Fund to Purchaser, less (ii) the amount of claims for indemnification
under this Article XI asserted by Sellers prior to the expiration of such six
(6) month period but not yet resolved ("Unresolved Claims"), and any unreleased
amount shall be retained by the Escrow Agent. Twelve (12) months after the
Closing Date, the Escrow Agent shall release the remaining amount of Purchaser's
Indemnity Escrow Fund to Purchaser, except that the Escrow Agent shall retain an
amount equal to the amount of the Unresolved Claims asserted prior to the
expiration of such twelve (12) month period. The Purchaser's Indemnity Escrow
Fund retained for Unresolved Claims shall be released by the Escrow Agent (to
the extent not utilized to pay Sellers for any such claims resolved in favor of
Sellers) upon their resolution in accordance with this Article XI.

          (b) Sellers' Indemnity Escrow Amount. On the Closing Date, Purchaser
shall pay to the Escrow Agent, in immediately available funds, to the account
designated by the Escrow Agent, the Sellers' Indemnity Escrow Amount (which
shall be deducted from the Purchase Price) in accordance with the terms of this
Agreement and the Indemnity Escrow Agreement. Any payment Sellers are obligated
to make to any Purchaser Indemnified Party pursuant to this Article XI shall be
paid from the Sellers' Indemnity Escrow Fund. Six (6) months after the Closing
Date, the Escrow Agent shall release fifty percent (50%) of (i) the then
existing amount of the Sellers' Indemnity Escrow Fund to Sellers, less (ii) the
amount of the Unresolved Claims asserted by Sellers prior to the expiration of
such six (6) month period, and any unreleased amount shall be retained by the
Escrow Agent. Twelve (12) months after the Closing Date, the Escrow Agent shall
release the remaining amount of the Seller's Indemnity Escrow Fund to Sellers,
except that the Escrow Agent shall retain an amount equal to the amount of the
Unresolved Claims asserted prior to the expiration of such twelve (12) month
period. The Sellers' Indemnity Escrow Fund retained for Unresolved Claims shall
be released by the Escrow Agent (to the extent not utilized to pay Purchaser for
any such claims resolved in favor of Purchaser) upon their resolution in
accordance with this Article XL

     11.6 Tax Treatment of Indemnity Payments. Sellers and Purchaser agree to
treat any indemnity payment made pursuant to this Article XI as an adjustment to
the Purchase Price for all Tax purposes. If, notwithstanding the treatment
required by the preceding sentence, any indemnification payment is determined to
be taxable to the party receiving such payment by any Taxing Authority, the
paying party shall also indemnify the party receiving such payment for any

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Taxes incurred by reason of the receipt of such payment and any Expenses
incurred by the party receiving such payment in connection with such Taxes (or
any asserted deficiency, claim, demand, action, suit, proceeding, judgment or
assessment, including the defense or settlement thereof, relating to such
Taxes). The amount of any Loss shall be reduced on account of any Tax benefit
actually realized by the party incurring such Loss.

NOTWITHSTANDING ANYTHING IN THIS AGREEMENT TO THE CONTRARY, IN NO EVENT SHALL
ANY PARTY OR THEIR AFFILIATES BE LIABLE UNDER ANY THEORY, INCLUDING NEGLIGENCE,
FOR CONSEQUENTIAL, INCIDENTAL, SPECIAL, PUNITIVE, EXEMPLARY OR INDIRECT DAMAGES
OR LOST PROFITS, DAMAGE TO REPUTATION, LOST BUSINESS OPPORTUNITIES, INTERFERENCE
WITH BUSINESS OPPORTUNITIES OR DIMINUTION OF VALUE.

                                   ARTICLE XII

                                      TAXES

     12.1 Transfer Taxes. (i) Purchaser and Sellers shall each be responsible
for (and shall indemnify and hold harmless each other against) half of any and
all Liabilities for any sales, use, stamp, documentary, filing, recording,
transfer, real estate transfer, stock transfer, gross receipts, registration,
duty, securities transactions or similar fees or taxes or governmental charges
(together with any interest or penalty, addition to tax or additional amount
imposed) as levied by any Taxing Authority in connection with the transactions
contemplated by this Agreement (collectively, "Transfer Taxes"), regardless of
the Person liable for such Transfer Taxes under Applicable Law and (ii) Sellers
or Purchaser, as required by Applicable Law, shall timely file or caused to be
filed all necessary documents (including all Tax Returns) with respect to
Transfer Taxes. Notwithstanding the foregoing, the Sellers shall seek to include
in the Sale Order a provision that Sellers' sale, transfer, assignment and
conveyance of the Purchased Assets to Purchaser hereunder shall be entitled to
the protections afforded under Section 1146(c) of the Bankruptcy Code. The
parties will reasonably cooperate to minimize any such taxes, including with
respect to delivery location.

     12.2 Prorations. All personal property taxes, or ad valorem obligations and
similar recurring taxes and fees on the Purchased Assets for taxable periods
beginning before, and ending after, the Closing Date, shall be prorated between
Purchaser and Sellers as of 12:01 a.m. eastern standard time on the Closing
Date. With respect to Taxes described in this Section 12.2, Sellers shall timely
file all Tax Returns due before the Closing Date with respect to such Taxes and
Purchaser shall prepare and timely file all Tax Returns due after the Closing
Date with respect to such Taxes. If one party remits to the appropriate Taxing
Authority payment for Taxes, which are subject to proration under this Section
12.2 and such payment includes the other party's share of such Taxes, such other
party shall promptly reimburse the remitting party for its share of such Taxes.

     12.3 Purchase Price Allocation. Not later than sixty (60) days after the
Closing Date, Purchaser shall prepare and deliver to Sellers copies of Form 8594
and any required exhibits thereto (the "Asset Acquisition Statement") allocating
the purchase price (including the Assumed Liabilities) among the Purchased
Assets in accordance with Section 1060 of the Code and the

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Treasury regulations thereunder. Purchaser shall prepare and deliver to Sellers
from time to time revised copies of the Asset Acquisition Statement (the
"Revised Statements") so as to report any matters on the Asset Acquisition
Statement that need updating (including purchase price adjustments, if any).
Sellers shall have a period of ten (10) days after the delivery of the Asset
Acquisition Statement or, if applicable, the last Revised Statement (the
"Allocation Response Period") to present in writing to Purchaser notice of any
objections Sellers may have to the allocations set forth therein (an "Allocation
Objections Notice"). Unless Sellers object within such period, the Asset
Allocation Statement or, if applicable, the last Revised Statement shall be
binding on the parties. If Sellers shall raise any objections within the
Allocation Response Period, Purchaser and Sellers shall negotiate in good faith
and use their commercially reasonable efforts to resolve such dispute. If the
parties fail to agree within fifteen (15) days after the delivery of the
Allocation Objections Notice, then Purchaser shall submit the Asset Acquisition
Statement or, if applicable, the last Revised Statement, including
modifications, if any, that Purchaser chooses to make as a result of its
negotiations with Sellers, to the Accountant for resolution by it. The disputed
items shall be submitted to the Accountant within fifteen (15) days following
such failure to agree. The determination of the Accountant shall be final and
binding on the parties and shall not be subject to appeal. The Accountant shall
resolve the dispute by selecting the proposed allocation submitted by either
Purchaser or Sellers which in the sole judgment of the Accountant most
accurately allocates the purchase price and the Assumed Liabilities among the
Purchased Assets in accordance with their relative fair market values, but not
by choosing any other formulation. The Accountant shall render such decision and
report to Purchaser and Sellers in writing, specifying the reasons for its
decision in reasonable detail, not later than thirty (30) days after the item
has been referred to it. The costs, fees and expenses of the Accountant shall be
borne equally by Sellers and Purchaser. The purchase price for the Purchased
Assets shall be allocated in accordance with the Asset Acquisition Statement or,
if applicable, the last Revised Statements, as finally determined, and all
income Tax Returns and reports filed by Purchaser and Sellers shall be prepared
consistently with such allocation.

     12.4 Cooperation on Tax Matters.

          (a) Purchaser and Sellers shall furnish or cause to be furnished to
each other, as promptly as practicable, such information and assistance relating
to the Purchased Assets and the Assumed Liabilities as is reasonably necessary
for the preparation and filing of any Tax Return, claim for refund or other
required or optional filings relating to Tax matters, for the preparation for
any Tax audit, for the preparation for any Tax protest, or for the prosecution
or defense of any suit or other proceeding relating to Tax matters.

          (b) Purchaser shall retain possession of all accounting, business,
financial and Tax records and information relating to the Purchased Assets or
the Assumed Liabilities that are in existence on the Closing Date and
transferred to Purchaser hereunder for a period of at least three (3) years from
the Closing Date. Purchaser shall give Sellers notice and an opportunity to
retain any such records in the event that Purchaser determines to destroy or
dispose of them after such period. In addition, from and after the Closing Date,
Purchaser shall provide access to Sellers (after reasonably detailed prior
notice and during normal business hours), to the books, records, documents and
other information relating to the Purchased Assets or the Assumed Liabilities as
is reasonably necessary for Sellers to properly prepare for, file, prove,
answer,

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prosecute and/or defend any Tax Return, claim, filing, tax audit, tax protest,
suit, proceeding or answer.

                                  ARTICLE XIII

                                  MISCELLANEOUS

     13.1 Expenses. Except for the Expense Reimbursement and as otherwise
expressly provided in this Agreement, each of Sellers and Purchaser shall bear
its own expenses incurred in connection with the negotiation and execution of
this Agreement and each other agreement, document and instrument contemplated by
this Agreement and the consummation of the transactions contemplated hereby and
thereby.

     13.2 Specific Performance. Sellers and Purchaser acknowledge and agree that
the breach of this Agreement would cause irreparable damage to the other and
that neither Sellers nor Purchaser will have an adequate remedy at law.
Therefore, the obligations of Sellers and Purchaser under this Agreement shall
be enforceable by a decree of specific performance issued by any court of
competent jurisdiction, and appropriate injunctive relief may be applied for and
granted in connection therewith. Such remedies shall, however, be cumulative and
not exclusive and shall be in addition to any other remedies which any party may
have under this Agreement or otherwise.

     13.3 Submission to Jurisdiction; Consent to Service of Process.

          (a) The parties hereto hereby irrevocably submit to the exclusive
jurisdiction of the Bankruptcy Court over any dispute arising out of or relating
to this Agreement or any of the transactions contemplated hereby and each party
hereby irrevocably agrees that all claims in respect of such dispute or any
suit, action proceeding related thereto may be heard and determined in the
Bankruptcy Court; provided, however, that in the event the Bankruptcy Court
abstains from exercising or declines to exercise jurisdiction with respect to
any matter provided for in this sentence or is without jurisdiction, such
abstention, refusal or lack of jurisdiction shall have no effect upon and shall
not control, prohibit or limit the exercise of jurisdiction of any other court
having competent jurisdiction with respect to any such matter. The parties
hereby irrevocably waive, to the fullest extent permitted by Applicable Law, any
objection which they may now or hereafter have to the laying of venue of any
such dispute brought in such court or any defense of inconvenient forum for the
maintenance of such dispute. Each of the parties hereto agrees that a judgment
in any such dispute may be enforced in other jurisdictions by suit on the
judgment or in any other manner provided by law.

          (b) Each of the parties hereto hereby consents to process being served
by any party to this Agreement in any suit, action or proceeding by the mailing
of a copy thereof in accordance with the provisions of Section 13.7.

     13.4 Waiver of Right to Trial by Jury. Each party to this Agreement waives
any right to trial by jury in any action, matter or proceeding regarding this
Agreement or any provision hereof.

                                       78

<PAGE>

     13.5 Entire Agreement; Amendments and Waivers. This Agreement (including
the schedules and exhibits hereto) and the Confidentiality Agreement represent
the entire understanding and agreement between the parties hereto with respect
to the subject matter hereof. This Agreement can be amended, supplemented or
changed, and any provision hereof can be waived, only by written instrument
making specific reference to this Agreement signed by the party against whom
enforcement of any such amendment, supplement, modification or waiver is sought.
No action taken pursuant to this Agreement, including without limitation, any
investigation by or on behalf of any party, shall be deemed to constitute a
waiver by the party taking such action of compliance with any representation,
warranty, covenant or agreement contained herein. The waiver by any party hereto
of a breach of any provision of this Agreement shall not operate or be construed
as a further or continuing waiver of such breach or as a waiver of any other or
subsequent breach. No failure on the part of any party to exercise, and no delay
in exercising, any right, power or remedy hereunder shall operate as a waiver
thereof, nor shall any single or partial exercise of such right, power or remedy
by such party preclude any other or further exercise thereof or the exercise of
any other right, power or remedy. All remedies hereunder are cumulative and are
not exclusive of any other remedies provided by law.

     13.6 Governing Law. This Agreement shall be governed by and construed in
accordance with the laws of the State of New York applicable to contracts made
and performed in such State.

     13.7 Notices. All notices and other communications under this Agreement
shall be in writing and shall be deemed given (i) when delivered personally by
hand (with written confirmation of receipt), (ii) when sent by facsimile (with
written confirmation of transmission) or (iii) one business day following the
day sent by overnight courier (with written confirmation of receipt), in each
case at the following addresses and facsimile numbers (or to such other address
or facsimile number as a party may have specified by notice given to the other
party pursuant to this provision):

          If to Sellers, to:

          aaiPharma Inc.
          2320 Scientific Park Drive
          Wilmington, NC 28405
          Facsimile: (910) 815-2387
          Attention: Ludo Reynders

          With a copy to:

          Fried, Frank, Harris, Shriver & Jacobson LLP
          One New York Plaza
          New York, NY 10004
          Facsimile: (212) 859-4000
          Attention: Jean Hanson, Esq.

          If to Purchaser, to:

                                       79

<PAGE>

          Xanodyne Pharmaceuticals, Inc.
          7300 Turfway Road
          Suite 300
          Florence, KY 41042
          Facsimile: (859) 371-7692
          Attention: Thomas P. Jennings, Esq.

          With a copy to:

          Weil, Gotshal & Manges LLP
          767 Fifth Avenue
          New York, NY 10153
          Facsimile: (212) 310-8007
          Attention: Lori R. Fife, Esq.
                     Simeon Gold, Esq.

     13.8 Severability. If any term or other provision of this Agreement is
invalid, illegal, or incapable of being enforced by any law or public policy,
all other terms or provisions of this Agreement shall nevertheless remain in
full force and effect so long as the economic or legal substance of the
transactions contemplated hereby is not affected in any manner materially
adverse to any party. Upon such determination that any term or other provision
is invalid, illegal, or incapable of being enforced, the parties hereto shall
negotiate in good faith to modify this Agreement so as to effect the original
intent of the parties as closely as possible in an acceptable manner in order
that the transactions contemplated hereby are consummated as originally
contemplated to the greatest extent possible.

     13.9 Binding Effect; Assignment. This Agreement shall be binding upon and
inure to the benefit of the parties and their respective successors and
permitted assigns. Nothing in this Agreement shall create or be deemed to create
any third party beneficiary rights in any person or entity not a party to this
Agreement except as provided below. No assignment of this Agreement or of any
rights or obligations hereunder may be made by either Sellers or Purchaser (by
operation of law or otherwise) without the prior written consent of the other
parties hereto and any attempted assignment without the required consents shall
be void; provided, however, that Purchaser may assign this Agreement and any or
all rights or obligations hereunder (including, without limitation, Purchaser's
rights to purchase the Purchased Assets and assume the Assumed Liabilities and
Purchaser's rights to seek indemnification hereunder) to any wholly-owned
Subsidiary of Purchaser); provided, further, however, in such event, Purchaser
shall remain bound by the terms of this Agreement. Upon any such permitted
assignment, the references in this Agreement to Purchaser shall also apply to
any such assignee unless the context otherwise requires.

     13.10 Non-Recourse. No past, present or future director, officer, employee,
incorporator, member, partner, equityholder, Affiliate, agent, attorney or
representative of Purchaser or Sellers or their respective Affiliates shall have
any liability for any obligations or liabilities of Purchaser or Sellers, as the
case may be, under this Agreement or the Purchaser Documents of or for any claim
based on, in respect of, or by reason of, the transactions contemplated hereby
and thereby.

                                       80

<PAGE>

     13.11 Time of Essence. With regard to all dates and time periods set forth
or referred to in this Agreement, including, without limitation, the deadline by
which the Approval Motion must be filed, the deadlines by which the Bidding
Procedures Order and Sale Order must be entered, and the deadline by which the
Closing Date must occur, each of the parties hereto acknowledge that time is of
the essence. The failure to meet the foregoing deadlines shall constitute a
default under this Agreement.

     13.12 Counterparts. This Agreement may be executed in one or more
counterparts, each of which will be deemed to be an original copy of this
Agreement and all of which, when taken together, will be deemed to constitute
one and the same agreement.

                                       81

<PAGE>

          IN WITNESS WHEREOF, the parties hereto have caused this Agreement to
be executed by their respective officers thereunto duly authorized, as of the
date first written above.

                                        XANODYNE PHARMACEUTICALS, INC.

                                        By: /s/ William A. Nuerge
                                            ------------------------------------
                                        Name: William A. Nuerge
                                        Title: Chief Executive Officer

                                        AAIPHARMA INC.

                                        By:
                                            ------------------------------------
                                        Name:
                                        Title:

                                        AAIPHARMA LLC

                                        By:
                                            ------------------------------------
                                        Name:
                                        Title:

                                       82

<PAGE>

          IN WITNESS WHEREOF, the parties hereto have caused this Agreement to
be executed by their respective officers thereunto duly authorized, as of the
date first written above.

                                        XANODYNE PHARMACEUTICALS, INC.

                                        By:
                                            ------------------------------------
                                        Name:
                                        Title:

                                        AAIPHARMA INC.

                                        By: /s/ Ludo J. Reynders
                                            ------------------------------------
                                        Name: Ludo J. Reynders
                                        Title: President/CEO

                                        AAIPHARMA LLC

                                        By: /s/ Ludo J. Reynders
                                            ------------------------------------
                                        Name: Ludo J. Reynders
                                        Title: President/CEO

<PAGE>

                                 FIRST AMENDMENT

                           TO ASSET PURCHASE AGREEMENT

          This First Amendment to the Asset Purchase Agreement (as defined
below), dated as of June 7,2005 (this "First Amendment"), is by and between
Xanodyne Pharmaceuticals, Inc., a Delaware corporation ("Purchaser"), aaiPharma
Ina, a Delaware corporation ("Parent"), and aaiPharma, LLC, a Delaware limited
liability company (together with Parent, "Sellers").

                                    RECITALS

     This First Amendment amends that certain Asset Purchase Agreement (the
"Asset Purchase Agreement"), by and among Sellers and Purchaser, dated as of May
6, 2003.

     Sellers and Purchaser desire to modify the Asset Purchase Agreement,
pursuant to Section 13.5 of the Asset Purchase Agreement, upon the terms and
conditions set forth in this First Amendment.

     Capitalized terms contained herein shall have the meaning ascribed to them
in the Asset Purchase Agreement, unless otherwise expressly set forth herein.

                                    AGREEMENT

     NOW THEREFORE, Sellers and Purchaser hereby agree as follows:

                                   AMENDMENTS

     The definition of "Alternative Transaction" in the Asset Purchase Agreement
is hereby amended and restated in its entirety to read as follows:

"Alternative Transaction" means (a) the sale (whether by stock sale, merger,
consolidation or otherwise) of all or a substantial portion of the capital stock
of Sellers, (b) the sale of all or any of the Purchased Assets pursuant to the
Bidding Procedures, or (c) a transaction or series of transactions outside or
independent of the Bidding Procedures that result in the Sellers realizing not
less than an aggregate of $75,000,000 in cash and/or fair market value of debt
and/or equity securities (such fair market value to be determined by the
Bankruptcy Court or, if Sellers shall not then be the subjects of a Chapter 11
Case, then jointly by Sellers and Purchaser or, failing such joint
determination, by an independent nationally recognized investment banking firm
jointly selected by Sellers and Purchaser or, failing such joint selection, by
such an independent nationally recognized investment banking firm selected by
two other investment banking firms selected one each by Sellers and Purchaser)
from the sale or transfer of Purchased Assets, in each case to a Person other
than Purchaser, excluding the sale of Inventory in the Ordinary Course of
Business; provided, however, that a sale by a chapter 7 trustee will not
constitute an "Alternative Transaction."

<PAGE>

     The definition of "Restructuring Transaction" in the Asset Purchase
Agreement is hereby amended and restated in its entirety to read as follows:

'"Restructuring Transaction' means (a) a recapitalization transaction involving,
in whole or in part, Sellers and its existing security holders or creditors, or
(b) a transaction or series of transactions, including by way of a plan of
reorganization, in connection with a chapter 11 liquidation or reorganization or
other continuation of Seller's business relating to some or all of the Purchased
Assets; provided, however, that a sale by a chapter 7 trustee will not
constitute an "Restructuring Transaction."

     Section 7.1 (a) of the Asset Purchase Agreement is hereby amended and
restated in its entirety to read as follows:

"(a) Sellers acknowledge and agree that Purchaser has expended considerable time
and expense in connection with this Agreement and the negotiation thereof and
the identification and quantification of assets of Sellers. In consideration
therefor, Sellers shall file with and seek the approval of the Bankruptcy Court
of the Approval Motion, including the Break-Up Fee and Expense Reimbursement,
and the entry by the Bankruptcy Court of the Bidding Procedures Order approving
the payment of the Break-Up Fee in an amount equal to Four Million Dollars
($4,000,000) and the Expense Reimbursement in an amount not to exceed One
Million Seven Hundred Fifty Thousand Dollars ($1,750,000) (not including any
amounts previously paid by Sellers) for Purchaser's reasonable out-of-pocket
documented expenses incurred in connection with the transactions contemplated
hereby and the financing thereof and deeming the Break-Up Fee and the Expense
Reimbursement as administrative priority expense claims under Sections 503(b)
and 507(a)(l) of the Bankruptcy Code."

     Section 7.1(d) of the Asset Purchase Agreement is hereby amended and
restated in its entirety to read as follows:

"(d) If on or prior to twelve (12) months following the date of termination of
this Agreement Sellers file with the Bankruptcy Court a Restructuring
Transaction or enter into a Restructuring Transaction, Purchaser shall have an
allowed administrative priority expense claim under Sections 503(b) and
507(a)(l) of the Bankruptcy Code for an Expense Reimbursement in an amount equal
to Three Million Dollars ($3,000,000) (in each case less any amount previously
paid to Purchaser in accordance with Section 7.1(b)), without regard to actual
expenses incurred, and Sellers shall pay such amount to Purchaser on the first
(1st) Business Day after consummation of such Restructuring Transaction,"

     Exhibit F of the Asset Purchase Agreement is hereby amended and restated in
its entirety to read as set forth in Annex A hereto.

     Exhibit I of the Asset Purchase Agreement is hereby amended and restated in
its entirety to read as set forth in Annex B hereto.

                                       3
<PAGE>

                                  MISCELLANEOUS

     This First Amendment contains the entire agreement of the parties with
respect to the subject matter covered in this First Amendment.

     This First Amendment shall be governed by and construed in accordance with
the laws of the State of New York applicable to contracts made and performed in
such State.

     Except as amended hereby, all terms, conditions and provisions of the Asset
Purchase Agreement remain in full force and effect, and the Asset Purchase
Agreement shall continue in full force and effect.

     This First Amendment may be executed in two or more counterparts, all of
which shall be considered one and the same agreement, and shall become effective
when one or more such counterparts have been signed by each of the parties and
delivered to the other party.

                      [Signature Page Immediately Follows]

                                        4

<PAGE>

          IN WITNESS WHEREOF, the parties hereto have caused this First
Amendment to be executed by their respective officers thereunto duly authorized,
as of the date first written above.

                                        XANODYNE PHARMACEUTICALS, INC.

                                        By: /s/ William A. Nuerge
                                            ------------------------------------
                                        Name: William A. Nuerge
                                        Title: Chief Executive Officer

                                        AAIPHARMA INC.

                                        By:
                                            ------------------------------------
                                        Name:
                                        Title:

                                        AAIPHARMA, LLC

                                        By:
                                            ------------------------------------
                                        Name:
                                        Title:

                                        5

<PAGE>

          IN WITNESS WHEREOF, the parties hereto have caused this First
Amendment to be executed by their respective officers thereunto duly authorized,
as of the date first written above.

                                        XANODYNE PHARMACEUTICALS, INC.

                                        By:
                                            ------------------------------------
                                        Name:
                                        Title:

                                        AAIPHARMA INC.

                                        By: /s/ Ludo J. Reynders
                                            ------------------------------------
                                        Name:
                                        Title:

                                        AAIPHARMA, LLC

                                        By: /s/ Ludo J. Reynders
                                            ------------------------------------
                                        Name:
                                        Title:

                                        6

<PAGE>

                                SECOND AMENDMENT

                                       TO

                            ASSET PURCHASE AGREEMENT

          This Second Amendment to the Asset Purchase Agreement (as defined
below), dated as of July 18, 2005 (this "Second Amendment"), is by and between
Xanodyne Pharmaceuticals, Inc., a Delaware corporation ("Purchaser"), aaiPharma
Inc., a Delaware corporation ("Parent"), and aaiPharma, LLC, a Delaware limited
liability company (together with Parent, "Sellers").

                                    RECITALS

          A. This Second Amendment amends that certain Asset Purchase Agreement
by and among Sellers and Purchaser, dated as of May 6, 2005 as amended by that
certain First Amendment to the Asset Purchase Agreement by and among Seller and
Purchasers dated as of June 7, 2005 (the "Asset Purchase Agreement").

          B. Sellers and Purchaser desire to further modify the Asset Purchase
Agreement, pursuant to Section 13.5 of the Asset Purchase Agreement, upon the
terms and conditions set forth in this Second Amendment.

          C. Capitalized terms contained herein shall have the meaning ascribed
to them in the Asset Purchase Agreement, unless otherwise expressly set forth
herein

                                    AGREEMENT

          NOW, THEREFORE, Sellers and Purchaser hereby agree as follows:

                                   ARTICLE XIV
                                   AMENDMENTS

          SECTION 1.1 - The following definitions set forth in Section 1.1 of
the Asset Purchase Agreement are hereby amended and restated as follows:

'"Manufacturing Agreement' means the agreement between Purchaser and Sellers
substantially in the form attached hereto as Annex A."

'"Services Agreement' means the agreement to provide services with respect to
the Marketed Products, Purchaser Developed Products, Lifecycle Products, and New
Products, substantially in the form attached hereto as Annex B."

          SECTION 3.1 Section 3.1 of the Asset Purchase Agreement is hereby
amended and restated in its entirety to read as follows:

<PAGE>

"Consideration. The aggregate consideration for the Purchased Assets shall be
(i) the payment by Purchaser to Seller, in the manner provided in Section 3.9
hereof, of $209,250,000, less the Development Costs, if any (the "Purchase
Price"), provided that if the Closing Date does not occur by October 8, 2005
(the "Adjustment Deadline"), the Purchase Price shall be reduced by $1,500,000
on each weekly anniversary of the Adjustment Deadline prior to the Closing Date
(the "Purchase Price Adjustment"), provided that the Purchase Price Adjustment
shall not be applicable to any week (or portion thereof) after the Adjustment
Deadline in which there shall be an uncured breach by Purchaser of covenant or
agreement contained in this Agreement which would result in a failure of a
condition set forth in Section 10.2 or 10.3 and all other conditions set forth
in Article X (other than conditions that by their nature are to be satisfied at
the Closing) to have been satisfied; provided, further, that in no event, shall
the Purchase Price Adjustment exceed $6,000,000 in the aggregate, (ii) the
assumption by Purchaser of the Assumed Liabilities, and (iii) the payment by
Purchaser to Sellers of royalty payments pursuant to Section 3.2. Commencing on
November 6, 2005 and provided that the Closing Date has not yet occurred,
Purchaser shall have the right to terminate this Agreement pursuant to Section
4.4; provided, however, that in the event Purchaser terminates this Agreement
pursuant to Section 4.4, Purchaser shall be paid the Expense Reimbursement on
the first (1st) Business Day after such termination and Purchaser shall remain
entitled to receive the Break-Up Fee in accordance with Section 7.1 upon the
satisfaction of the conditions set forth therein."

          SCHEDULE 1.1(K) Schedule 1.1(k) of the Asset Purchase Agreement is
hereby amended and restated in its entirety to read as set forth in Annex C
hereto.

          SCHEDULE 2.7(I) Schedule 2.7(i) is hereby deleted in its entirety.

          SCHEDULE 2.7(II) Schedule 2.7(ii) is hereby deleted in its entirety.

          EXHIBIT E Exhibit E is hereby deleted in its entirety.

          EXHIBIT G Exhibit G is hereby deleted in its entirety.

                                   ARTICLE XV
                                  MISCELLANEOUS

     15.1 This Second Amendment contains the entire agreement of the Parties
with respect to the subject matter covered in this Second Amendment.

     15.2 This Second Amendment shall be governed by and construed in accordance
with the laws of the State of New York applicable to contracts made and
performed in such State.

     15.3 Except as amended hereby, all terms, conditions and provisions of the
Asset Purchase Agreement remain in full force and effect, and the Asset Purchase
Agreement shall continue in full force and effect.

     15.4 This Second Amendment may be executed in two or more counterparts, all
of which shall be considered one and the same agreement, and shall become
effective when one

<PAGE>

or more such counterparts have been signed by each of the Parties and delivered
to the other Party.

                      [Signature Page Immediately Follows]

<PAGE>

          IN WITNESS WHEREOF, the Parties hereto have caused this Second
Amendment to be executed by their respective officers thereunto duly authorized,
as of the date first written above.

                                        XANODYNE PHARMACEUTICALS, INC.

                                        By: /s/ William A. Nuerge
                                            ------------------------------------
                                        Name: William A. Nuerge
                                        Title: Chief Executive Officer

                                        AAIPHARMA INC.

                                        By:
                                            ------------------------------------
                                        Name:
                                        Title:

                                        AAIPHARMA, LLC.

                                        By:
                                            ------------------------------------
                                        Name:
                                        Title:

<PAGE>

          IN WITNESS WHEREOF, the Parties hereto have caused this Second
Amendment to be executed by their respective officers thereunto duly authorized,
as of the date first written above.

                                        XANODYNE PHARMACEUTICALS, INC.

                                        By:
                                            ------------------------------------
                                        Name: William A. Nuerge
                                        Title: Chief Executive Officer

                                        AAIPHARMAINC

                                        By: /s/ Gregory S. Bentley
                                            ------------------------------------
                                        Name: Gregory S. Bentley
                                        Title: Executive VP and General Counsel

                                        AAIPHARMA, LLC.

                                        By: /s/ Gregory S. Bentley
                                            ------------------------------------
                                        Name: Gregory S. Bentley
                                        Title: Vice President<PAGE>

                                                                    Exhibit 10.9

          Confidential Materials omitted and filed separately with the
         Securities and Exchange Commission. Asterisks denote omissions.

                                                                  EXECUTION COPY

                            MASTER SERVICES AGREEMENT

     This Master Services Agreement (the "Agreement") is made and entered into
this 25th day of July, 2005 (the "Effective Date"), by and between AAI
Development Services, a division of aaiPharma Inc. ("AAI DS") having a place of
business at 2320 Scientific Park Dr., Wilmington, NC 28405 and Xanodyne
Pharmaceuticals, Inc., a Delaware corporation ("Purchaser") having a place of
business at 7300 Turfway Road, Suite 300, Florence, KY 41042. Purchaser and AAI
DS are referred to singly as "Party" and jointly as "Parties" throughout this
Agreement.

                                   BACKGROUND:

     A. aaiPharma Inc., aaiPharma LLC and Purchaser entered into that certain
Asset Purchase Agreement dated the 6th day of May, 2005, as amended as of June
7, 2005 and July 18, 2005 (the "APA").

     B. It is a condition precedent to the Closing that the Parties enter into
this Agreement.

     C. AAI DS is in the business of providing (i) analytical services (MD/MV),
analytical (routine), RTP special analytical services, raw material laboratory
services, physical chemistry testing, stability services (stability setup,
protocol development, storage, analytical testing, and photostability studies),
biotechnology testing, microbiology services, bioanalytical services,
formulation development, specialized manufacturing (pilot scale and clinical
trial material), project management for the aforementioned services, management
of bioavailability/bioequivelance (BA/BE) Phase I clinical trials (including
clinical supplies distribution, pallet storage, study project management, data
management statistics, biostatistics, medical affairs assistance and
pharmacovigilence assistance) (collectively, "Base Services"); (ii) quality
control and assurance assistance (including stability studies oversight and
batch record review), medical affairs assistance and pharmacovigilence
assistance and regulatory reporting assistance services (collectively, the
"Additional Services"); and (iii) management of Phase II, III and IV clinical
trials (including study project management, data management, biostatistics,
medical affairs assistance and pharmacovigilence assistance) (collectively, the
"Additional Clinical Trial Services," and together with the Base Services and
the Additional Services, the "Services").

     D. Purchaser considers the proposed work as critical to its success and
requires that all work performed under this Agreement meet generally accepted
industry standards of quality. Purchaser desires to obtain such Services from
AAI DS throughout the Term (as defined below) of this Agreement in accordance
with the terms set forth herein and in accordance with a defined specification
and scope of work to be mutually agreed upon by the Parties in writing,
including any change orders, as further described below (each hereinafter a
"Service Contract").

<PAGE>

     E. On May 10, 2005, aaiPharma Inc. and certain of its domestic affiliates
(collectively the "Debtors") filed for chapter 11 bankruptcy protection (the
"Bankruptcy Cases") in the Bankruptcy Court for the District of Delaware (Case
No. 05-11341).

     F. The Debtors are authorized to continue to operate their businesses and
manage their properties as debtors in possession pursuant to sections 1107(2)
and 1108 of the Bankruptcy Code.

     NOW THEREFORE, for and in consideration of the mutual covenants and
agreements set forth hereinafter and for other good and valuable consideration,
the receipt and sufficiency of which is hereby acknowledged, the parties hereto
do hereby agree as follows:

                                   ARTICLE I

                               SCOPE OF AGREEMENT

     1.1 Unless it does not have the expertise or resources, as determined by
Purchaser and AAI DS collectively in the exercise of their reasonable judgment,
AAI DS will be engaged to perform one hundred percent (100%) of Purchaser's
requirements for Base Services for the Term with respect to (i) the Marketed
Products, the Lifecycle Products and the New Products, and (ii) pursuant to
Section 3.4 of the APA, any Pain Products containing (a) diclofenac and/or
propoxyphene or (b) an opioid/APAP combination or an opioid/NSAID combination
that Purchaser decides to independently develop (collectively, the "Independent
Pain Products," together with the Marketed Products, the Lifecycle Products and
the New Products, the "Services Products"). Notwithstanding the foregoing,
should AAI DS and Purchaser not be in agreement with respect to whether AAI DS
has the expertise or resources to perform the duties requested, Purchaser shall
make final determination as to which Services are performed by AAI DS, using
Purchaser's reasonable judgment. For avoidance of doubt, Purchaser must engage
AAI DS to perform the Base Services, provided it is deemed to have the proper
expertise and resources, even though Purchaser has the ability and/or expertise
to perform such Base Services on its own behalf by Purchaser's employees.

     1.2 Unless it does not have the expertise or resources, as determined by
Purchaser and AAI DS collectively in the exercise of their reasonable judgment,
AAI DS will be engaged to perform 100% of Purchaser's requirements for
Additional Services for the Term with respect to Services Products.
Notwithstanding the foregoing, should AAI DS and Purchaser not be in agreement
with respect to whether AAI DS has the expertise or resources to perform the
duties requested, Purchaser shall make final determination as to which Services
are performed by AAI DS, using Purchaser's reasonable judgment. For avoidance of
doubt, unlike with respect to the Base Services, Purchaser is not required to
engage AAI DS to perform the Additional Services if Purchaser wishes to perform
such Additional Services on its own behalf by Purchaser's employees.

     1.3 Unless it does not have the expertise or resources, as determined by
Purchaser and AAI DS collectively in the exercise of their reasonable judgment,
AAI DS will be engaged to perform 100% of Purchaser's requirements for
Additional Clinical Trial Services for the Term with respect to Services
Products; provided, however, that (i) for avoidance of doubt, Purchaser

                                        2

<PAGE>

must engage AAI DS to perform the Additional Clinical Trial Services even though
Purchaser has the ability and/or expertise to perform such Additional Clinical
Trial Services on its own behalf by Purchaser's employees, provided however that
if, taking into account the nature of the project and the capabilities of AAI
DS, Purchaser can reasonably demonstrate the greater likelihood of success of
the project or a greater economic benefit to both Parties, Purchaser will be
permitted to conduct the applicable clinical trial using either internal
resources or a third party, and (ii) in the event Purchaser exercises its rights
to conduct the applicable clinical trial using either internal resources or a
third party under clause (i) of this Section 1.3 with respect to a Services
Product and Sellers are entitled to a royalty under the APA with respect to such
Services Product, Sellers shall be entitled to receive the royalty as if Sellers
or their respective Subsidiaries developed such Services Product all the way up
to commercialization. Notwithstanding the foregoing, in no event will Purchaser
use a price quoted by AAI DS to solicit competitive bids for Additional Clinical
Trial Services. Notwithstanding the foregoing, should AAI DS and Purchaser not
be in agreement with respect to whether Purchaser can reasonably demonstrate the
greater likelihood of success of the project or a greater economic benefit to
both Parties by having the clinical trials performed by internal resources or a
third party, Purchaser shall make such final determination, using Purchaser's
reasonable judgment.

     1.4 The Parties hereby agree to enter into a Service Contract for each
engagement of the performance of Services. Each Service Contract shall include,
among other things, the scope of the Services to be performed, the fees to be
paid by Purchaser to AAI DS for the performance of the Services, and the payment
schedule for those fees. Service Contracts shall be in the form set forth in
Exhibit B attached hereto and incorporated herein by reference.

     1.5 Services provided by AAI DS shall comply in all material respects with
Applicable Laws.

     1.6 The Parties understand that AAI DS shall use commercially reasonable
efforts to initiate, conduct and complete the Services as set forth in a Service
Contract in a timely fashion. Purchaser understands and agrees that completing
the Services as set forth in the Service Contract assumes the full cooperation
of Purchaser as well as other third parties.

                                   ARTICLE II

                             PROJECT IMPLEMENTATION

     2.1 The execution of a Service Contract shall authorize AAI DS to proceed
under the terms and conditions of this Agreement and such Service Contract.

     2.2 AAI DS shall use commercially reasonable efforts to anticipate the
scope of activities necessary to complete Services established by a Service
Contract. However, Service Contracts constitute both Parties' informed estimate
of those Services necessary to satisfactorily complete the project and are based
upon the Parties' then current knowledge of the factual situation as well as the
then current regulatory environment. Therefore, the scope of proposed Services
(and the related fees and timeline) may require modification of the Service
Contract during the course of performance. In the event additional or different
Services are required, AAI DS shall notify Purchaser immediately and shall not
be authorized or required to perform such

                                        3

<PAGE>

modified Services unless and until Purchaser requests such modification in
writing, and AAI DS agrees in writing, to perform such additional or different
Services. If AAI DS does not have the expertise or resources or is otherwise
unable to perform the Services as modified, as determined by Purchaser and AAI
DS collectively in the exercise of their reasonable judgment, Purchaser may
utilize a third party for the performance of such modified Services.
Notwithstanding the foregoing, should AAI DS and Purchaser not be in agreement
with respect to whether AAI DS has the expertise or resources or is otherwise
unable to perform the Services as modified, Purchaser shall make final
determination as to which Services are performed by AAI DS, using Purchaser's
reasonable judgment. If AAI DS is willing to provide such additional or
different Services, AAI DS shall promptly acknowledge Purchaser's written
authorization by issuing a change order for such additional or different
Services.

     2.3 Purchaser shall have the right to review and approve the qualifications
of all personnel AAI DS assigns to perform work under this Agreement and any
Service Contract, such approval not to be unreasonably withheld or delayed.
Purchaser shall also have the right to designate, for good cause, that any such
personnel be removed or replaced. AAI DS may also replace personnel when
necessary and appropriate.

     2.4 AAI DS will use commercially reasonable efforts to complete the agreed
upon Services within the limits set forth in the executed Service Contract. The
Parties will agree upon target timelines for completion of the Services.
However, the Parties recognize that the Services to be provided hereunder are
not subject to precise advance determination, unless otherwise stated in the
Service Contract or otherwise. To the extent there is any discrepancy between
the provisions of this Agreement and a Service Contract, the terms and
conditions of this Agreement shall govern.

     2.5 Acceptance will occur when deliverables under an applicable Service
Contract meet the agreed upon acceptance criteria as described in the applicable
Service Contract. If the deliverables do not meet the acceptance criteria when
they are offered by AAI DS to Purchaser for acceptance, Purchaser will give AAI
DS detailed written notification of the deficiency or non-conformance within
thirty (30) days after receipt of the applicable deliverable. AAI DS then shall,
within thirty (30) days of receipt of such written notification, either correct
the deficiency or non-conformance or provide Purchaser with a plan reasonably
acceptable to Purchaser for correcting that deficiency or non-conformance. If
the deficiency or non-conformance is not corrected or if an acceptable plan is
not established during such period, then, upon request by Purchaser, AAI DS
shall refund Purchaser all fees paid by Purchaser relating to such deliverable
as specified in the applicable Service Contract.

     2.6 The Parties agree that all disputes between them relating to this
Agreement shall be submitted for informal resolution to their respective chief
executive officers and any remaining dispute shall be submitted to a panel of
three arbitrators, with each Party choosing one panel member and the third
member (the "Third Member") chosen by the first two panel members. The Third
Member will be experienced in pharmaceutical development services. The
proceedings shall be conducted in accordance with the Commercial Dispute
Resolution Procedures (the "CDRP") of the American Arbitration Association and
shall be conducted in a location mutually acceptable to the Parties. The award
of the arbitrators shall include a written explanation of their decision, shall
be limited to remedies otherwise available in court and shall

                                        4

<PAGE>

be binding upon the Parties and enforceable in any court of competent
jurisdiction. The panel will set and follow an expedited schedule for the
proceeding so that the panel's final decision and explanation will be issued not
later than 45 days after engagement of the services of the Third Member (unless
extended by mutual agreement of the Parties or by the panel), and shall utilize
"Expedited Procedures" (as defined in the CDRP). The losing party shall pay the
costs of any such arbitration, which costs shall not be Out-of-Pocket Expenses
(as defined in Section 3.7.)

                                   ARTICLE III

                          PAYMENT FOR SERVICES RENDERED

     3.1 The initial prices for the Services are set forth on Exhibit A (the
"Purchase Prices"). Purchaser agrees to pay for Services according to the
applicable Service Contract. A deposit of [**]% of the projected cost of each
project shall be due upon the signing of the applicable Service Contract.

     3.2 AAI DS may increase the Purchase Prices effective as of each January 1
during the Term by the amount equal to the percentage change in the Producers
Price Index, Drugs and Pharmaceuticals, Preparations, ethical (prescription)
(Code 0635) (or any comparable successor index) during the twelve month period
ending on the September 30 immediately preceding the January 1 Purchase Price
adjustment. AAI DS shall provide written notification of any increase in the
Purchase Prices by the November 1 prior to the January 1 effective date of the
increase in Purchase Prices.

     3.3 During the first year of the Initial Term ("Year 1"), Purchaser shall
purchase or offer to purchase, in accordance with this Section 3.3
(collectively, "Acquire") Services from AAI DS for amounts, inclusive of
Out-of-Pocket Expenses (as defined in Section 3.7) ("Service Amounts") that, in
the aggregate, are equal to at least $10,000,000 (the "Year 1 Minimum"). During
the second year of the Initial Term ("Year 2"), Purchaser shall Acquire Service
Amounts that, in the aggregate, are equal to at least $5,000,000 (as may be
adjusted, the "Year 2 Minimum"). During the third year of the Initial Term
("Year 3", and collectively with Year 1 and Year 2, the "Subject Years"),
Purchaser shall Acquire Service Amounts that, in the aggregate, are equal to at
least $5,000,000 (as may be adjusted, the "Year 3 Minimum", and collectively
with the Year 1 Minimum and the Year 2 Minimum, the "Minimum Purchase Amounts");
provided, however, that if on or prior to April 30, 2006, there has been
completion of the appropriate Phase I PK Study or Studies for the Darvocet-N XR
Product and agreement or consent by the FDA to allow the initiation of the Phase
III efficacy studies based on the Phase I data, the Year 2 Minimum and the Year
3 Minimum shall each be $10,000,000 (subject to adjustment as provided for in
Section 3.5 and Section 3.6 (as applicable)).

(a)  The Service Amounts that shall be credited towards Purchaser's satisfaction
     of the Minimum Purchase Amount in each of the Subject Years shall be for
     the actual Services in respect of which payments are accrued during the
     applicable Subject Year plus the Out-of-Pocket Expenses that are invoiced
     to Purchaser by AAI DS during the applicable Subject Year plus any
     Out-of-Pocket Expenses that are invoiced on or prior to 45 days after the
     end of the applicable Subject Year but which relate to the applicable
     Subject Year. The Parties acknowledge and agree that, notwithstanding
     anything herein or in any

                                        5

<PAGE>

     Service Contract to the contrary, AAI DS shall be entitled to invoice, and
     Purchaser shall pay, all Service Amounts that are credited towards
     Purchaser's satisfaction of the Minimum Purchase Amount for an applicable
     Subject Year.

(b)  Each of Purchaser and AAI DS acknowledges and agrees that (i) Services
     which Purchaser has engaged AAI DS to provide with regard to XP12B on and
     after the Effective Date shall be credited towards Purchaser's satisfaction
     of the Minimum Purchase Amount for the applicable Subject Year and (ii) any
     Services performed by AAI DS with regard to the Odyssey Product engaged by
     Purchaser or a third party shall be credited towards Purchaser's
     satisfaction of the Minimum Purchase Amount for the applicable Subject
     Year. For the avoidance of doubt, any out-of-pocket expenses invoiced to a
     third-party by AAI DS related to Services performed for such third-party
     shall only be credited against Purchaser's satisfaction of the applicable
     Minimum Purchase Amount if such out-of-pocket expenses paid by such
     third-party are Out-of-Pocket Expenses, as defined in Section 3.7 below
     (i.e., if Purchaser pays a 20% margin on such Out-of-Pocket Expenses).

(c)  If Purchaser offers to engage AAI DS to provide Services for which AAI DS
     has the expertise and resources to perform, as determined in AAI DS's
     reasonable discretion (solely for purposes of this clause (c)), and AAI DS
     does not choose to perform the Services, an amount equal to the replacement
     cost for the same Services incurred by Purchaser shall be credited towards
     Purchaser's satisfaction of the Minimum Purchase Amount for the applicable
     Subject Year in which such amounts are incurred by Purchaser.

(d)  For the avoidance of doubt, Reimbursable Expenses under the Odyssey
     Co-Development Agreement shall not be credited towards Purchaser's
     satisfaction of any Minimum Purchase Amount, other than Services as
     contemplated in Section 3.3(b) above and out-of-pocket expenses related to
     such Services invoiced by AAI DS that are Out-of-Pocket Expenses (as
     defined in Section 3.7 below). Notwithstanding anything to the contrary
     herein, Purchaser shall not be permitted to credit any amount against any
     Minimum Purchase Amount if (i) AAI DS is determined not to have the
     expertise or resources to perform the Service in accordance with the
     provisions of Article 2 of this Agreement or is otherwise unable to perform
     the Services, or (ii) except as provided in clause (c) of this Section 3.3,
     Purchaser employs or otherwise contracts for a third party to perform the
     Services.

     3.4 In the event that Purchaser does not Acquire in a Subject Year Service
Amounts that, in the aggregate, equal at least the then applicable Minimum
Purchase Amount, Purchaser shall pay to AAI DS, within sixty (60) calendar days
after the end of such Subject Year, the difference between (i) the applicable
Minimum Purchase Amount for such Subject Year and (ii) the amount of the
aggregate Service Amounts that Purchaser has accrued (in respect of Services)
and paid (in respect of Out-of-Pocket Expenses) in respect of such Subject Year.

     3.5 In the event that Purchaser has Acquired in Year 1 Service Amounts
that, in the aggregate, equal more than the Year 1 Minimum, then the amount of
such excess, but not to

                                        6

<PAGE>

exceed twenty percent (20%) of the Year 1 Minimum (i.e., $2 million), shall be
credited towards Purchaser's satisfaction of the Year 2 Minimum.

     3.6 In the event that Purchaser has Acquired in Year 2 Service Amounts
that, in the aggregate, equal more than the Year 2 Minimum, then the amount of
such excess, but not to exceed twenty percent (20%) of the Year 2 Minimum (i.e.,
$1 million or $2 million, as applicable), shall be credited towards Purchaser's
satisfaction of the Year 3 Minimum.

     3.7 In addition, Purchaser will reimburse AAI DS for reasonable and
customary documented out-of-pocket expenses for raw materials which shall be
invoiced by AAI DS to Purchaser at cost plus a 20 percent (20%) handling fee
(the "Raw Material Expenses"). Other out-of-pocket expenses, such as travel and
pass through expenses (e.g., investigator fees), will be expensed at cost on a
"pass through basis" plus a twenty percent (20%) handling fee ("Other Expenses",
and collectively, with the Raw Material Expenses, the "Out-of-Pocket Expenses").
AAI DS shall obtain prior written consent for any individual Other Expense in
excess of $10,000. Purchaser agrees to pay in advance any substantial pass
through expenses.

     3.8 Unless otherwise set forth in the applicable Service Contract, AAI DS
shall invoice Purchaser on a calendar month basis for Services rendered and
expenses incurred during the previous calendar month. Invoices are due and
payable within thirty (30) days of date of invoice. All payments to AAI DS shall
be made in U.S. dollars. Invoice balances not remitted within thirty (30) days
of receipt of invoice shall be subject to a one and one-half percent (1.5%) per
month interest charge. Should any part of the invoice be in dispute, Purchaser
shall pay the remainder of the undisputed amount according to the terms and
conditions described herein while said dispute is being resolved.

     3.9 The fees payable under this Agreement shall not, and shall not be
construed to, include local, state, federal or foreign sales and use taxes, if
any, and any such taxes shall be assumed and paid by Purchaser.

     3.10 AAI DS shall not subcontract any of the Services as set forth in a
Service Contract, other than to an Affiliate of AAI DS, without the prior
written consent of Purchaser, which consent shall not be unreasonably withheld
or delayed.

     3.11 Any amounts payable to Purchaser hereunder, including, without
limitation, claims for indemnification, shall be administrative expense priority
claims in the Bankruptcy Cases pursuant to sections 503 and 507(a)(l) of the
Bankruptcy Code.

     3.12 The obligations of AAI DS under this Agreement or the Service
Contracts shall not be discharged by entry of an order confirming a plan of
reorganization in the Bankruptcy Cases and, pursuant to section 1141 (d)(4) of
the Bankruptcy Code, AAI DS has waived such discharge.

                                       7

<PAGE>

                                   ARTICLE IV

                              INTELLECTUAL PROPERTY

     4.1 AAI DS hereby assigns to Purchaser all right, title and interest in
Intellectual Property discovered by AAI DS in the course of providing Services
which are directly and solely related to the Services (collectively, the
"Project IP"); provided, that, notwithstanding the foregoing, to the extent such
Project IP relates to, or is an improvement upon, Licensed Assets or Licensed
Intellectual Property (such Project IP, collectively, "Licensed Project IP"), in
lieu of the assignment provided above, AAI DS hereby grants to Purchaser a
non-exclusive, perpetual, transferable, royalty-free license (with a right of
sublicense without consent) in the Territory to all of AAI DS's right, title and
interest in such Licensed Project IP. For purposes of clarity, and
notwithstanding anything in this Agreement or any Service Contract to the
contrary, AAI DS will continue to own any Intellectual Property included in the
Project IP that was owned or independently developed by AAI DS prior to
providing any Services or developed independent of such Services (the "AAI DS
Proprietary Technology") and has the right to use such Intellectual Property in
AAI DS's sole discretion. In the event that Purchaser chooses to further develop
and/or commercialize a technology comprising, in whole or in part, AAI DS
Proprietary Technology, and the AAI DS Proprietary Technology is not already
licensed to Purchaser under the APA, Purchaser must first obtain a license for
such development and/or commercialization from AAI DS, to be memorialized by a
separate writing negotiated in good faith by AAI DS and Purchaser.

     4.2 AAI DS will, at the expense and the written request of Purchaser, do
all reasonable acts and execute all documents as Purchaser may reasonably
request to transfer to and vest in Purchaser the ownership and registration of
all Intellectual Property rights that may exist in such owned Project IP and to
provide such license rights in the Licensed Project IP.

Purchaser acknowledges that AAI DS is in the business of providing Services for
a variety of organizations other than Purchaser. Accordingly, except to the
extent otherwise set forth in the APA, nothing in this Agreement shall preclude
or limit AAI DS from providing Services or developing materials for itself or
other clients, or from utilizing the general knowledge gained during the course
of its performance hereunder, the AAI DS Proprietary Technology or the Licensed
Project IP to perform similar Services for other clients, provided that such
provision of Services or development of materials does not constitute a breach
of confidentiality under Article V herein or any provisions of the APA.

The forgoing terms and provisions of this Article IV are in addition to the
relevant terms and provisions of the APA; provided that, to the extent any of
the terms and provisions set forth in this Article IV are inconsistent with the
terms of the APA, the terms of the APA shall govern.

                                       8

<PAGE>

                                    ARTICLE V

                                 CONFIDENTIALITY

     5.1 Section 8.9(d) of the APA is incorporated herein by reference and shall
be binding on the Parties, and as incorporated herein, shall continue until the
fifth (5th) anniversary of the expiration or earlier termination of this
Agreement.

     5.2 Neither Party (nor any of their respective Affiliates) shall issue any
press release or make any public announcement with respect to this Agreement and
the transactions contemplated hereby without obtaining the prior written consent
of the other Party (such consent not to be unreasonably withheld or delayed),
except as may be required by Applicable Law upon the advice of counsel and only
if the disclosing Party provides the non-disclosing Party with a reasonable
opportunity to first review the release or other public announcement.

                                   ARTICLE VI

                          REPRESENTATION AND WARRANTIES

     6.1 Representations and Warranties of AAI DS. AAI DS hereby represents and
warrants as follows:

     (a) AAI DS shall comply in all material respects with all Applicable Laws
in the performance of the Services.

     (b) The execution, delivery and performance of this Agreement and the
consummation of the transactions contemplated hereby are within AAI DS's powers
and have been duly authorized by all necessary action on the part of AAI DS.
This Agreement has been duly executed and delivered by AAI DS and, assuming the
due execution and delivery hereof by Purchaser and approval by the Bankruptcy
Court, constitutes legal, valid and binding obligations of AAI DS, enforceable
against AAI DS in accordance with its terms, except as such enforceability may
be limited by applicable bankruptcy, insolvency, moratorium, reorganization or
similar laws from time to time in effect which affect the enforcement of
creditors' rights generally.

     (c) The execution, delivery and performance by AAI DS of this Agreement
does not and will not (i) contravene or conflict with the organizational
documents of aaiPharma Inc., (ii) contravene or conflict with or constitute a
violation of any Applicable Laws, or (iii) materially breach or constitute a
material default under the provisions of any material contract, agreement or
instrument to which it is a party or by which it is bound.

     (d) AAI DS is not debarred and has not and shall not knowingly and
intentionally use in any capacity the services of any Third Person debarred
under subsections 306(a) or (b) of the Generic Drug Enforcement Act of 1992.

     (e) All Services performed by AAI DS pursuant to this Agreement will meet
generally accepted industry standards of quality.

                                       9

<PAGE>

     (f) AAI DS shall not seek to reject or modify this Agreement or any Service
Contract in the Bankruptcy Cases including, without limitation, pursuant to any
plan of reorganization or liquidation filed in the Bankruptcy Cases and AAI DS
shall not seek to modify this Agreement or any Service Contract in any
subsequent chapter 11 cases commenced under the Bankruptcy Code.

     EXCEPT AS SET FORTH IN THIS SECTION 6.1, AAI DS MAKES NO REPRESENTATIONS OR
WARRANTIES, EXPRESS OR IMPLIED, AND SPECIFICALLY DISCLAIMS ALL SUCH
REPRESENTATIONS AND WARRANTIES, INCLUDING, WITHOUT LIMITATION, ANY IMPLIED
WARRANTIES OF MERCHANTABILITY, INFRINGEMENT, TITLE OR FITNESS FOR A PARTICULAR
PURPOSE.

     6.2 Representations and Warranties of Purchaser. Purchaser hereby
represents and warrants as follows:

     (a) The execution, delivery and performance of this Agreement and the
consummation of the transactions contemplated hereby are within Purchaser's
powers and have been duly authorized by all necessary action on the part of
Purchaser. This Agreement has been duly executed and delivered by Purchaser and,
assuming the due execution and delivery hereof by AAI DS and approval by the
Bankruptcy Court, constitutes legal, valid and binding obligations of Purchaser,
enforceable against Purchaser in accordance with its terms, except as such
enforceability may be limited by applicable bankruptcy, insolvency, moratorium,
reorganization or similar laws from time to time in effect which affect the
enforcement of creditors' rights generally.

     (b) The execution, delivery and performance by Purchaser of this Agreement
does not and will not (i) contravene or conflict with the organizational
documents of Purchaser, (ii) contravene or conflict with or constitute a
violation of any Applicable Laws, or (iii) materially breach or constitute a
material default under the provisions of any material contract, agreement or
instrument to which it is a party or by which it is bound.

                                   ARTICLE VII

                                 INDEMNIFICATION

     7.1 By Purchaser. Purchaser hereby indemnifies AAI DS and its directors,
officers, employees, Affiliates, stockholders, agents, attorneys,
representatives, successors and permitted assigns (collectively, the "AAI DS
Indemnified Parties") against and agrees to hold each of them harmless from any
and all losses, liabilities, obligations, damages, costs and expenses ("Losses")
incurred by any AAI DS Indemnified Party to the extent based upon, attributable
to or resulting from: (a) any misrepresentation or breach of warranty made by
Purchaser in this Agreement, (b) any breach of any covenant or agreement made or
to be performed by Purchaser pursuant to this Agreement and/or applicable
Service Contracts, or (c) any Services provided to the Purchaser pursuant to
this Agreement and/or applicable Service Contracts, unless such Losses arise
from claims for which AAI DS would be required to provide indemnification
pursuant to Section 7.2.

                                       10

<PAGE>

     7.2 By AAI DS. AAI DS hereby indemnifies Purchaser and its directors,
officers, employees, Affiliates, stockholders, agents, attorneys,
representatives, successors and permitted assigns (collectively, the "Purchaser
Indemnified Parties") against and agrees to hold each of them harmless from any
and all Losses incurred by any Purchaser Indemnified Party to the extent based
upon, attributable to or resulting from: (a) any misrepresentation or breach of
warranty made by AAI DS in this Agreement and (b) any breach of any covenant or
agreement made or to be performed by AAI DS pursuant to this Agreement and/or
applicable Service Contracts; provided, however, that in no event shall AAI DS
have indemnification obligations in excess of two times the aggregate fees
received by AAI DS under the applicable Service Contracts.

     7.3 Indemnification Procedures

     (a) In the event that any Legal Proceeding shall be instituted or that any
claim or demand shall be asserted by any Person in respect of which payment may
be sought under Section 7.1 or Section 7.2 hereof (regardless of the limitations
set forth in Section 7.2) ("Indemnification Claim"), the indemnified party shall
reasonably and promptly cause written notice of the assertion of any
Indemnification Claim of which it has knowledge which is covered by this
indemnity to be forwarded to the indemnifying party. The indemnifying party
shall have the right, at its sole expense, to be represented by counsel of its
choice, which must be reasonably satisfactory to the indemnified party, and to
defend against, negotiate, settle or otherwise deal with any Indemnification
Claim which relates to any Losses indemnified against hereunder; provided that
the indemnifying party shall have acknowledged in writing to the indemnified
party its unqualified obligation to indemnify the indemnified party as provided
hereunder. If the indemnifying party elects to defend against, negotiate, settle
or otherwise deal with any Indemnification Claim which relates to any Losses
indemnified against hereunder, it shall within twenty (20) Business Days (or
sooner, if the nature of the Indemnification Claim so requires) notify the
indemnified party of its intent to do so. If the indemnifying party elects not
to defend against, negotiate, settle or otherwise deal with any Indemnification
Claim which relates to any Losses indemnified against hereunder, fails to notify
the indemnified party of its election as herein provided or contests its
obligation to indemnify the indemnified party for such Losses under this
Agreement, the indemnified party may defend against, negotiate, settle or
otherwise deal with such Indemnification Claim. If the indemnified party defends
any Indemnification Claim, then the indemnifying party shall reimburse the
indemnified party for any and all Expenses of defending such Indemnification
Claim upon submission of periodic bills. If the indemnifying party shall assume
the defense of any Indemnification Claim, the indemnified party may participate,
at his or its own expense, in the defense of such Indemnification Claim;
provided, however, that such indemnified party shall be entitled to participate
in any such defense with separate counsel at the expense of the indemnifying
party if (i) so requested by the indemnifying party to participate or (ii) in
the reasonable opinion of counsel to the indemnified party a conflict or
potential conflict exists between the indemnified party and the indemnifying
party that would make such separate representation advisable; and provided,
further, that the indemnifying party shall not be required to pay for more than
one such counsel for all indemnified parties in connection with any
Indemnification Claim. The parties hereto agree to cooperate fully with each
other in connection with the defense, negotiation or settlement of any such
Indemnification Claim. Notwithstanding anything in this Section 7.3 to the
contrary, neither the indemnifying party nor the indemnified party shall,
without the written

                                       11

<PAGE>

consent of the other party, settle or compromise any Indemnification Claim or
permit a default or consent to entry of any judgment unless the claimant and
such party provide to such other party an unqualified release from all liability
in respect of the Indemnification Claim. Notwithstanding the foregoing, if a
settlement offer solely for money damages is made by the applicable third party
claimant, and the indemnifying party notifies the indemnified party in writing
of the indemnifying party's willingness to accept the settlement offer and,
subject to the applicable limitations of Section 7.2, pay the amount called for
by such offer, and the indemnified party declines to accept such offer, the
indemnified party may continue to contest such Indemnification Claim, free of
any participation by the indemnifying party, and the amount of any ultimate
liability with respect to such Indemnification Claim that the indemnifying party
has an obligation to pay hereunder shall be limited to the lesser of (A) the
amount of the settlement offer that the indemnified party declined to accept
plus the Losses of the indemnified party relating to such Indemnification Claim
through the date of its rejection of the settlement offer or (B) the aggregate
Losses of the indemnified party with respect to such Indemnification Claim. If
the indemnifying party makes any payment on any Indemnification Claim, the
indemnifying party shall be subrogated, to the extent of such payment, to all
rights and remedies of the indemnified party to any insurance benefits or other
claims of the indemnified party with respect to such Indemnification Claim.

     (b) After any final judgment or award shall have been rendered by a
Governmental Body of competent jurisdiction and the expiration of the time in
which to appeal therefrom, or a settlement shall have been consummated, or the
indemnified party and the indemnifying party shall have arrived at a mutually
binding agreement with respect to an Indemnification Claim hereunder, the
indemnified party shall forward to the indemnifying party notice of any sums due
and owing by the indemnifying party pursuant to this Agreement with respect to
such matter and the indemnifying party shall be required to pay all of the sums
so due and owing to the indemnified party by wire transfer of immediately
available funds within ten (10) Business Days after the date of such notice.

     (c) The failure of the indemnified party to give reasonably prompt notice
of any Indemnification Claim shall not release, waive or otherwise affect the
indemnifying party's obligations with respect thereto except to the extent that
the indemnifying party can demonstrate actual loss and prejudice as a result of
such failure.

     7.4 Disclaimer of Damages. Notwithstanding anything in this Agreement to
the contrary, in no event shall either Party be liable to the other under any
theory, including negligence, for any indirect, incidental, consequential,
special or exemplary damages or lost profits.

     7.5 Exclusive Remedy. The right to indemnification and other rights under
this Article 7 shall constitute Purchaser's (and its Affiliates) and AAI DS's
(and its Affiliates) sole and exclusive remedies with respect to any and all
claims arising under or relating to this Agreement and/or any applicable Service
Contract. In furtherance of the foregoing, each of Purchaser and AAI DS hereby
waives, and shall cause any Affiliates to waive, to the fullest extent permitted
by Applicable Law, any and all rights, claims and causes of action that they may
have against any other Party or its Affiliates in connection with such
transactions, except those arising under Article 7.

                                       12

<PAGE>

                                  ARTICLE VIII

                              TERM AND TERMINATION

     8.1 Unless earlier terminated in accordance with this Article 8, this
Agreement shall take effect and commence on the Effective Date and continue in
effect for seven (7) years ("Initial Term"). In addition, after the expiration
of the Initial Term, the Agreement will automatically renew for consecutive two
(2) year terms ("Renewal Period") until either of the Parties terminates this
Agreement by providing the other Party with at least sixty (60) days' written
notice prior to the end of the Initial Term or applicable Renewal Period. The
Initial Term, together with any Renewal Period(s), is referred to herein as the
"Term".

     8.2 Notwithstanding Section 8.1 herein, this Agreement may be terminated as
follows:

(a)  immediately upon the delivery of written notice by one Party, if the other
     Party materially breaches any of the provisions of this Agreement and such
     breach is not cured within sixty (60) calendar days after the giving of
     written notice thereof (or if cure has been commenced during such period,
     if it is not diligently pursued to completion);

(b)  immediately upon delivery of written notice by one Party, if the other
     Party has been unable to perform its obligations hereunder for one hundred
     twenty (120) calendar days by reason of force majeure (as defined in
     Section 10.11); or

(c)  immediately if (i) the Bankruptcy Court enters an order in the Bankruptcy
     Cases appointing a trustee, examiner with expanded powers or responsible
     officer in the Bankruptcy Cases, (ii) any of the Bankruptcy Cases are
     converted to a case(s) under chapter 7 of the Bankruptcy Code or (iii) the
     Bankruptcy Cases are dismissed.

     8.3 Upon termination or expiration of this Agreement:

(a)  AAI DS shall stop all Services, each Party shall return to the other any
     Confidential Information of such other Party and AAI DS shall transfer all
     Project IP to Purchaser as provided in Section 4.2 of this Agreement upon
     payment by Purchaser as set forth in Section 8.3(b) below.

(b)  Purchaser shall be obligated to pay to AAI DS the cost of all Services
     completed and expenses incurred, as set forth in the relevant Service
     Contract(s) then in effect at the time of termination in accordance with
     the terms and conditions set forth in this Agreement. Purchaser shall be
     obligated to pay for all unused supplies and materials that were ordered by
     AAI DS in order to perform the Services and, upon such payment, Purchaser
     shall be permitted to take delivery of such unused supplies and materials.
     AAI DS shall use commercially reasonable efforts to minimize the costs
     associated with the cessation of Services.

     8.4 AAI DS and Purchaser agree that the following provisions shall survive
the termination of this Agreement: Article IV, Article V, Article VII, Section
8.3, Section 8.4 and Article X.

                                       13

<PAGE>

                                   ARTICLE IX

                               RECORDS AND AUDITS

     9.1 AAI DS agrees to maintain records of all Services performed under this
Agreement in accordance with the FDA archival guidelines. Upon reasonable prior
written notice (not less than fifteen (15) Business Days), during regular
business hours, and at mutually agreed upon times, Purchaser may, at its own
cost and expense, review one time each calendar year AAI DS's quality control
procedures and records, and review the records of AAI DS relating to the
Services performed and expenses incurred to assure compliance with all
provisions of this Agreement, in each case with a representative of AAI DS
present. If Purchaser determines in its reasonable judgment that AAI DS's
quality control procedures and records are not satisfactory or identifies
significant deficiencies or problems with such records or expenses, Purchaser
reserves the right to perform additional visits until remedied.

     9.2 In the event of an inspection by any governmental or regulatory agency
concerning the Services performed hereunder, AAI DS shall notify Purchaser
promptly upon learning of such an inspection, shall supply Purchaser with copies
of any correspondence or portions or correspondence relating to Purchaser's
materials and shall inform Purchaser of the general findings and outcomes of
such inspections. Purchaser shall reimburse AAI DS for actual time and
reasonable expenses incurred by AAI DS in connection with any inspection
pursuant to this Section 9.2 to the extent the inspection is directly related to
the Services performed by AAI DS on behalf of Purchaser. AAI DS shall provide
Purchaser with an invoice detailing such time and expenses. AAI DS shall invoice
Purchaser at its then current rates applicable at the time of such review.
Purchaser shall also be invoiced for any incidental expenses AAI DS incurs
resulting from such review. Payment of such invoice shall be in accordance with
Section 3.8 herein. Notwithstanding the foregoing, in the event that the
inspection determines that Services were not in material compliance with any
Applicable Law, Purchaser shall not be obligated to make any payments for any
expenses related to such inspection.

                                    ARTICLE X

                                  MISCELLANEOUS

     10.1 Successors and Assigns. Neither Party may assign this agreement
without the other Party's prior written consent, which consent shall not be
unreasonably withheld or delayed, except that Purchaser may assign its rights or
obligations hereunder only to an Affiliate or third party that purchases
substantially all of the assets of Purchaser relating to the Services Products
provided that such Affiliate or third party agrees in writing to be bound by all
terms and conditions of this Agreement.

     10.2 Notices. Any notice required or permitted under this Agreement shall
be in writing, shall specifically refer to this Agreement, and shall be sent by
hand, recognized overnight courier, confirmed facsimile transmission, or
registered or certified mail service, postage prepaid, return receipt requested,
to the following addresses or facsimile numbers of the Parties:

                                       14

<PAGE>

     Purchaser:

     Xanodyne Pharmaceuticals, Inc.
     7300 Turfway Road
     Suite 300
     Florence, KY 41042
     Facsimile: (859) 371-7692
     Attention: Thomas P. Jennings, Esq.

     AAI DS:

     President
     aaiPharma Inc.
     2320 Scientific Park Drive
     Wilmington, NC 28405
     Fax: 910-815-2387

     With a copy sent to:

     aaiPharma Inc.
     2320 Scientific Park Dr.
     Wilmington, NC 28409
     Attn: General Counsel
     Fax: (910)815-2387

All notices under this Agreement shall be deemed received (i) upon receipt when
sent by hand, (ii) two (2) Business Days after deposit with a recognized
overnight courier, (iii) upon confirmation of delivery when sent by facsimile
and (iv) five (5) Business Days after deposit in registered or certified mail
service. A party may change its contact information immediately upon written
notice to the other party in the manner provided in this Section.

     10.3 Waiver. No delay on the part of AAI DS or Purchaser in exercising any
right, power or privilege hereunder shall operate as a waiver thereof, nor shall
any waiver on the part of either Party of any right, power or privilege
hereunder operate as a waiver of any other right, power or privilege hereunder,
nor shall any single or partial exercise of any right, power or privilege
hereunder preclude any other or further exercise thereof or the exercise of any
other right, power or privilege hereunder. Any provision of this Agreement may
be waived if, and only if, such waiver is in writing and signed by the Party
against whom the waiver is to be effective.

     10.4 Entire Agreement. This Agreement, the APA and the Service Contracts
executed pursuant to this Agreement constitute the entire agreement between the
Parties with respect to the subject matter hereof and supersede all prior
agreements, understanding and negotiations, both written and oral, between the
Parties with respect to the subject matter of this Agreement.

     10.5 Amendment. This Agreement may be modified or amended only by written
agreement of the Parties hereto.

                                       15

<PAGE>

     10.6 Counterparts. This Agreement may be executed by facsimile and in any
number of counterparts, each of which shall be deemed an original but all of
which together shall constitute a single instrument. This Agreement may be
executed on signature pages exchanged by facsimile, in which event each Party
shall promptly deliver to the others such number of original executed copies as
the others may reasonably request.

     10.7 Governing Law; Jurisdiction.

     (a) This Agreement shall be governed and construed in accordance with the
laws of the State of New York excluding any choice of law rules which may direct
the application of the law of another state.

     (b) Any action or proceeding arising out of or relating to this Agreement
or any of the transactions contemplated hereby may be brought in the United
States District Court for the Southern District of New York, and each of the
Parties irrevocably submits to the exclusive jurisdiction of such court in any
such action or proceeding, waives any objection it may now or hereafter have to
venue or to convenience of forum, agrees that all claims in respect of such
action or proceeding shall be heard and determined only in such court and agrees
not to bring any action or proceeding arising out of or relating to this
Agreement or the transactions contemplated hereby in any other court.

     10.8 Severability. If any provision of this Agreement is held to be
illegal, invalid or unenforceable under any present or future law, and if the
rights or obligations of any Party hereto under this Agreement will not be
materially and adversely affected thereby, (a) such provision will be fully
severable, (b) this Agreement will be construed and enforced as if such illegal,
invalid or unenforceable provision had never comprised a part hereof, (c) the
remaining provisions of this Agreement will remain in full force and effect and
will not be affected by the illegal, invalid or unenforceable provision or by
its severance herefrom, and (d) in lieu of such illegal, invalid or
unenforceable provision, there will be added automatically as a part of this
Agreement a legal, valid and enforceable provision as similar to the terms to
such illegal, invalid or unenforceable provision as may be possible and
reasonably acceptable to the Parties herein. Notwithstanding the foregoing, the
Parties acknowledge that it is their intent that this Agreement and all of the
Service Contracts constitute one agreement and that neither Party may assume
certain Service Contracts and reject other Service Contracts or this Agreement
in any subsequent chapter 11 case.

     10.9 No Third Party Rights. Except as otherwise expressly set forth herein,
no provision of this Agreement shall be deemed or construed in any way to result
in the creation of any rights or obligations in any Person not a Party to this
Agreement.

     10.10 Exhibits. The Exhibits referenced in this Agreement are an integral
part of this Agreement and are incorporated herein by reference.

     10.11 Force Majeure. If either Party is prevented from complying, either
totally or in part, with any of the terms or provisions set forth herein by
reason of force majeure, including, by way of example and not of limitation,
fire, flood, explosion, storm, hurricane, strike, lockout or other labor
dispute, riot, war, rebellion, accidents, acts of God, acts of governmental
agencies

                                       16

<PAGE>

or instrumentalities, failure of suppliers or any other similar or dissimilar
cause, in each case to the extent beyond its control despite its commercially
reasonable efforts to avoid, minimize, and resolve such cause as promptly as
possible, said Party shall (a) provide written notice of same to the other
Party, and (b) subject to the obligations set forth above in this Section 10.11
with respect to said Party's efforts to remove the disability, its obligations
that are prevented from compliance by such force majeure are suspended, without
liability, during such period of force majeure. Said notice shall be provided
within five (5) business days of the occurrence of such event and shall identify
the requirements of this Agreement or such of its obligations as may be
affected. The Party so affected shall give to the other Party a good faith
estimate of the continuing effect of the force majeure condition and the
duration of the affected Party's nonperformance.

     10.12 No Other Relationship. It is expressly agreed that AAI DS, on the one
hand, and Purchaser, on the other hand, shall be independent contractors and
that nothing contained herein shall be deemed to create any joint venture or
partnership between the Parties hereto, and, except as is expressly set forth
herein, neither Party shall have any right by virtue of this Agreement to bind
the other Party in any manner whatsoever.

     10.13 Non-Solicitation. Purchaser agrees that, except as otherwise
permitted by Sections 8.9 and 9.1 of the APA, neither it nor its Affiliates
will, commencing on the date that the Bankruptcy Court enters the Sale Order and
continuing until one (1) year following the expiration or termination of this
Agreement: (i) knowingly hire a person who has been an employee of AAI DS or its
Affiliates during the two (2) years prior to such hiring, or (ii) directly or
indirectly solicit to employ the employees of AAI DS or its Affiliates, provided
that newspaper and internet advertisements to fill job openings shall not be
deemed to be "solicitation" hereunder.

     10.14 Definitions. Capitalized terms used but not otherwise defined herein
shall have the meaning given to them in the APA.

                                       17

<PAGE>

                                        EXECUTION PAGE TO MASTER SERVICES
                                        AGREEMENT

     IN WITNESS WHEREOF, the Parties hereto have executed this Agreement as of
the date first above written.

                                        XANODYNE PHARMACEUTICALS, INC.

                                        By: /s/ S.A. Stamp
                                            ------------------------------------
                                        Printed Name: S.A. STAMP
                                        Title: CHIEF FINANCIAL OFFICER

                                        AAI DEVELOPMENT SERVICES, A DIVISION OF
                                        AAIPHARMA INC.

                                        By:
                                            ------------------------------------
                                        Printed Name:
                                                      --------------------------
                                        Title:
                                               ---------------------------------

<PAGE>

                                        EXECUTION PAGE TO MASTER SERVICES
                                        AGREEMENT

     IN WITNESS WHEREOF, the Parties hereto have executed this Agreement as of
the date first above written.

                                        XANODYNE PHARMACEUTICALS, INC.

                                        By:
                                            ------------------------------------
                                        Printed Name:
                                                      --------------------------
                                        Title:
                                               ---------------------------------

                                        AAI DEVELOPMENT SERVICES, A DIVISION OF
                                        AAIPHARMA INC.

                                        By: /s/ Ludo J. Reynders
                                            ------------------------------------
                                        Printed Name: Ludo J. Reynders
                                        Title: President/CEO

<PAGE>

                                    Exhibit A

                                 Purchase Prices

BILLING RATES - NON-CLINICAL

<TABLE>
<CAPTION>
TYPE OF WORK                                              HOURLY RATES
------------                                              ------------
<S>                                       <C>
Analytical (MD/MV)                                                               $[**]
Analytical (Rountine)                                                            $[**]
RTP Special Analytical                                                           $[**]
Biotechnology Testing                                                            $[**]
Project Management                                                               $[**]
Formulations Development                                                         $[**]
Physical Chemistry Testing                                                       $[**]
Manufacturing - Wilmington                                                       $[**]
Manufacturing - Charleston                                                       $[**]
Non-Manufacturing - Charleston                                                   $[**]
Microbiology                                                                     $[**]
Raw Material Laboratory                                                          $[**]
Kansas (BA-HPLC/SBA)                                                             $[**]
Kansas (BA-MS)                                                                   $[**]
Statistics                                                                       $[**]
Regulatory                                                                       $[**]
Validations                                                                      $[**]
CDS Pallet Storage                                                        $[**]/pallet
Stability Set-Up & Protocol Generation                         $[**]/lot/configuration
Stability Storage
(with Analytical Testing)                                $[**]/month/lot/configuration
Photostability Storage                         $[**]/month/lot/configuration, UV & Vis
(ICH, Option 2 with Analytical Testing)
Photostability Storage                    $[**]/month/lot/configuration, Full Spectrum
(ICH, Option 1 with Analytical Testing)
Shipment (Ambient Condition)                                            $[**]/shipment
Shipment (Refrigerated Condition)                                       $[**]/shipment
Lab Support for Darvocet N-100                                                   $[**]
   Raw Material Testing
   Release Testing
BIOAVAILABILITY/BIOEQUIVILENCE (BA/BE)                                        Variable
   Depends Upon:
   Number of Subjects
   Number of Beds Occupied
   Subject Confinement
   Subject Remuneration
</TABLE>

<PAGE>

<TABLE>
<S>                                       <C>
   Blood Draw Schedule
   Number of Return Samples
   Staffing Required
   ADE Profile for the Drug, etc.
</TABLE>

<PAGE>

                                    Exhibit B

                                Service Contract

                                SERVICE CONTRACT

[insert name and address of Client]

Telephone: [insert #]
Fax: [insert #]
Email: [insert address]

SERVICE CONTRACT: [insert SE #]
TITLE:
ISSUED: [insert date]

OBJECTIVE/SCOPE:

[to be completed by contract generator]

SUMMATION OF SERVICES:

[to be completed by contract generator]

<PAGE>

THE TERMS AND PROVISIONS OF THE FOLLOWING ATTACHED APPENDICES ARE INCORPORATED
HEREIN BY REFERENCE AND SHALL BE BINDING ON THE PARTIES:

<TABLE>
<S>            <C>
APPENDIX I     DESCRIPTION OF SERVICES
APPENDIX II    PAYMENT SCHEDULE AND TERMS
APPENDIX III   GENERAL TERMS AND CONDITIONS
</TABLE>

THE SERVICES DESCRIBED IN THIS SERVICE CONTRACT, INCLUDING THE APPENDICES
HERETO, SHALL BE REFERRED TO HEREIN AS THE "SERVICES."

THE PHARMACEUTICAL PRODUCT COVERED BY SERVICES UNDER THIS SERVICE CONTRACT SHALL
BE REFERRED TO HEREIN AS THE "PRODUCT."

THIS SERVICE CONTRACT SHALL BECOME BINDING ON THE PARTIES IF SIGNED BY AN
AUTHORIZED REPRESENTATIVE OF PURCHASER AND RETURNED TO AAI WITHIN 30 DAYS OF THE
DATE HEREOF.

THIS SERVICE CONTRACT IS BEING ENTERED INTO PURSUANT TO THAT CERTAIN MASTER
SERVICES AGREEMENT BETWEEN THE PARTIES DATED ________, 2005 (THE "MASTER
SERVICES AGREEMENT"), AND THE SERVICES PERFORMED HEREUNDER SHALL BE GOVERNED BY
THE TERMS OF THIS SERVICE CONTRACT AND THE MASTER SERVICES AGREEMENT. IN THE
EVENT OF CONFLICT BETWEEN THE TERMS OF THIS SERVICE CONTRACT AND THE MASTER
SERVICES AGREEMENT, THE TERMS OF THE MASTER SERVICES AGREEMENT SHALL GOVERN.

AAIPHARMA, INC. FOR ITS DIVISION,
AAI DEVELOPMENT SERVICES                XANODYNE PHARMACEUTICALS, INC.

-------------------------------------   ----------------------------------------
Reviewed and Approved by:               Printed Name of Authorized
XXXX                                    Representative
Manager

-------------------------------------   ----------------------------------------
Date                                    Signature

-------------------------------------   ----------------------------------------
Reviewed and Approved by:               Date
Michael W. George
Executive Vice President

                                        ----------------------------------------
                                        Purchase Order Number

PLEASE RETURN SIGNED DOCUMENT:

XXXX
Project Manager, Product Development
Group

<PAGE>

AAI DEVELOPMENT SERVICES
2320 SCIENTIFIC DRIVE
WILMINGTON, N.C. 28405
Telephone: XXX.XXX.XXXX
Facsimile: XXX.XXX.XXXX
E-mail: XXXX.XXX@aaidevelopment.com

<PAGE>

                                   APPENDIX I
                             DESCRIPTION OF SERVICES

[to be completed by contract generator]

<PAGE>

                                   APPENDIX II
                           PAYMENT SCHEDULE AND TERMS

The estimated cost for the Services outlined in this Service Contract is
$XXX,XXX plus materials and storage as follows:

<TABLE>
<CAPTION>
DESCRIPTION OF SERVICES   ESTIMATED COST
-----------------------   --------------
<S>                       <C>
                          $
                          $
                          $
TOTAL                     $XXX,XXX
</TABLE>

In addition, Purchaser will be charged for all out-of-pocket costs and/or
expenses associated with the Services outlined herein in accordance with the
Master Services Agreement.

PAYMENT SCHEDULE

<TABLE>
<CAPTION>
PAYMENT              PAYMENT DESCRIPTION               AMOUNT
-------   ------------------------------------------   --------
<S>       <C>                                          <C>
  1       Pre-payment due upon signature of contract   $ XX,XXX
  2       [LIST OTHER MILESTONES]                      $ XX,XXX
  3                                                    $ XX,XXX
             TOTAL                                     $XXX,XXX
</TABLE>

<PAGE>

                                  APPENDIX III
                          GENERAL TERMS AND CONDITIONS

A. REQUIREMENTS. Purchaser will supply AAI DS with this Service Contract, or a
copy of it, signed by the appropriate authorized Purchaser representative.
Purchaser will also supply AAI DS with a purchase order number and prepayment in
the amount of $[XXX,XXX].

B. TERMINATION. Unless earlier terminated pursuant hereto, this Service Contract
shall continue in full force and effect until the Services to be provided
hereunder have been completed. This Service Contract may be terminated
immediately by one party, if the other party materially breaches any of the
provisions of this Service Contract and such breach is not cured within sixty
(60) calendar days after the giving of written notice thereof (or if cure has
been commenced during such period, if it is not diligently pursued to
completion). In the event of such termination, Purchaser will be obligated to
pay the cost of all Services completed and expenses incurred through the date of
such termination in accordance with the terms hereof and for all unused supplies
and materials that were ordered by AAI DS in order to perform the Services, plus
reasonable project shutdown costs.

C. SAFETY INFORMATION. Purchaser warrants that it will provide AAI DS with all
necessary safety information concerning chemical entities it supplies to AAI DS,
to ensure the safe handling, storage, usage, shipment and disposal of such
chemical entities. Purchaser is responsible for labeling and all other
information relevant to the Product.

D. SAMPLES. Unless otherwise designated by Purchaser in writing, any and all
materials received and associated with this Service Contract will be treated as
laboratory testing samples only, not for use in humans. After the final
stability time point, by completion or cancellation of the stability study, AAI
DS will retain any sample overage in the controlled stability storage
environment for a period of two months. After that time the samples will
automatically be returned to Purchaser or destroyed by appropriate means in
Wilmington, NC. Please initial and date one selection:

          Purchaser would like for AAI DS to ___ return ___ destroy the
                               remaining samples.

If the disposition of the samples is not indicated, the samples will be returned
to Purchaser at the end of the two month retain period. All shipping charges
will be Purchaser's responsibility. [ONLY APPLICABLE IF STABILITY STUDIES ARE
INCLUDED IN SERVICES]

<PAGE>

                  FIRST AMENDMENT TO MASTER SERVICES AGREEMENT

     This First Amendment to Master Services Agreement (this "Amendment") is
made by and between AAI Development Services, a division of aaiPharma Inc. ("AAI
DS"), and Xanodyne Pharmaceuticals, Inc. ("Purchaser"), and is effective as of
the ___ day of August, 2005 (the "Amendment Effective Date").

     WHEREAS, AAI DS and Purchaser have entered into that certain Master
Services Agreement dated July 25, 2005 (the "Agreement").

     WHEREAS, AAI DS and Purchaser now desire to amend the Agreement.

     NOW THEREFORE, for good and valuable consideration, the receipt and
sufficiency of which are hereby acknowledged, AAI DS and Purchaser hereby amend
and modify the Agreement and otherwise agree as follows:

     1. The following sentence shall be added to the end of Section 1.2 of the
Agreement: "Notwithstanding anything in this Agreement or a Service Contract to
the contrary, to the extent the Services to be performed pursuant to a Service
Contract are Additional Services and Purchaser wishes to perform such Additional
Services on its own behalf by Purchaser's employees, then Purchaser may
terminate the applicable Service Contract only with respect to such Additional
Services upon no less than sixty (60) days written notice to AAI DS."

     2. Continuing Effect. Except as otherwise expressly modified and/or amended
herein, the terms and conditions of the Agreement remain in full force and
effect.

     3. Headings; Capitalized Terms. The captions and headings used in this
Amendment are for the convenience of the parties and shall not be utilized to
interpret, construe or define the provisions of the Agreement or this Amendment.
Any capitalized terms used herein and not defined shall have the definitions
assigned to them in the Agreement.

     4. Counterparts; Facsimile. This Amendment may be executed in one or more
counterparts, each of which shall be deemed an original but all of which taken
together shall constitute one and the same document. This Amendment may be
executed by facsimile. The parties agree that facsimile copies of signatures
have the same effect as original signatures.

     DATED as of the Amendment Effective Date, and executed by:

AAI Development Services,               Xanodyne Pharmaceuticals, Inc.
a division of aaiPharma Inc.

By: /s/ Ludo Reynders                   By: /s/ William A. Nuerge
    ---------------------------------       ------------------------------------
Name: Ludo Reynders                     Name: William A. Nuerge
Title: President and CEO                Title: CEO

<PAGE>

                                    EXHIBIT A

                          SERVICES AGREEMENT AMENDMENT

                     AMENDMENT TO MASTER SERVICES AGREEMENT

     This Amendment to the Master Services Agreement ("Amendment") is made by
and between AAIPharma Inc. ("AAI") and Xanodyne Pharmaceuticals, Inc., a
Delaware corporation ("Xanodyne"), and is effective as of the 25th day of May,
2006 (the "Effective Date").

     WHEREAS, Xanodyne and AAI Development Services, a then division of AAI,
entered into the Master Services Agreement, dated July 25, 2005 (the
"Agreement");

     WHEREAS, the AAI Development Services division of AAI has been dissolved,
leaving AAI as the successor in interest of AAI Development Services under the
Agreement; and

     WHEREAS, Xanodyne and AAI desire to amend the Agreement upon the terms and
conditions set forth in this Amendment.

     NOW, THEREFORE, Xanodyne and AAI hereby agree as follows:

     1. Capitalized terms used, but not otherwise defined herein, shall have the
meaning given to them in the Agreement. All references in the Agreement to "AAI
Development Services" are hereby replaced with references to "AAIPharma Inc."
and references to "AAI DS" are hereby replaced with references to "AAI."

     2. The first sentence of Section 3.3 of the Agreement is amended and
restated in its entirety to read as follows: During the first year of the
Initial Term ("Year 1"), Purchaser shall purchase or offer to purchase, in
accordance with this Section 3.3 (collectively, "Acquire") Services from AAI for
amounts, inclusive of Out-of-Pocket Expenses (as defined in Section 3.7)
("Service Amounts") that, in the aggregate, are equal to at least $9,500,000
(the "Year 1 Minimum").

     3. The words "$2 million" in Section 3.5 shall be deleted and replaced with
"$1.9 million".

     4. This Amendment contains the entire agreement of the Parties with respect
to the subject matter covered in this Amendment.

     5. Except as otherwise expressly modified or amended herein, the terms and
conditions of the Agreement remain in full force and effect.

<PAGE>

     6. This Amendment may be executed in one or more counterparts, each of
which shall be deemed an original but all of which taken together shall
constitute one and the same document. In addition, this document may be executed
by facsimile, and the parties agree that facsimile copies of signatures shall
have the same effect as original signatures.

     7. This Amendment shall be governed by and construed in accordance with the
laws of the State of New York applicable to contracts made and performed in such
State.

                      [Signature Page Immediately Follows]

<PAGE>

     IN WITNESS WHEREOF, the Parties hereto have caused this Amendment to be
executed by their respective officers thereunto duly authorized, as of the
Effective Date.

XANODYNE PHARMACEUTICALS, INC.          AAIPHARMA INC.

By: /s/ William A. Nuerge               By: /s/ Vito Mangiardi
    ---------------------------------       ------------------------------------
Name: William A. Nuerge                 Name: Vito Mangiardi
Title: CEO                              Title: President, North American
                                               Operations

Dated: 5/18/06                          Dated: 5/25/06

                                        3

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