Document:

Exhibit 10.8

 

CLINICAL TRIAL SERVICES AGREEMENT AMENDMENT NO. 3

 

RADIUS HEALTH, INC., a Delaware corporation (“Radius”) and NORDIC BIOSCIENCE CLINICAL DEVELOPMENT VII A/S, a Danish corporation (“NB”) that is a wholly-owned subsidiary of Nordic Bioscience Clinical Development A/S entered into a Clinical Trial Services Agreement dated March 29, 2011 (“Agreement”) and Work Statement NB-3 under the Agreement (“Work Statement NB-3”) as of February 21, 2013 (“Effective Date”), and entered into an Amendment No. 1 to Work Statement NB-3 as of February 28, 2014 (as amended, “Work Statement NB-3”), and Amendment No. 2 to Work Statement NB-3 as of March 23, 2015(“Effective Date”).

 

The parties wish to enter into this Amendment No. 3 effective as of July 8, 2015 (“Amendment Date”). Capitalized terms used in this Amendment No. 3 and not defined herein are used with the meanings ascribed to them in this Agreement.

 

NOW THEREFORE, in consideration of the mutual promises contained in the Agreement and for other good and valuable consideration the receipt and adequacy of which each of the parties does hereby acknowledge, the parties hereby agree to the terms of this Amendment No. 3 as follows:

 

1. Radius Monitoring of United States study sites in period 2 of the BA058-05-005 study:

 

(a)  At Radius’s request, Radius will perform monitoring of US study sites in the period from the 6 month visit until the 24 month visit in a Period 2 extension of the clinical study entitled: BA058-05-005 “An Extension Study to Evaluate 24 Months of Standard-of-Care Osteoporosis Management Following Completion of 18 Months of BA058 or Placebo Treatment in Protocol BA058-05-003”. The purpose of this Amendment No. 3 is to introduce monitoring of US sites by Radius. The Clinical Monitoring Plan version 4 dated 08July2015 documents the change in monitoring responsibilities.

 

2.  Ratification.  Except to the extent expressly amended by this Amendment No. 3, all of the terms, provisions and conditions of the Agreement are hereby ratified and confirmed and shall remain in full force and effect.

 

3.  General.  This Amendment No. 3 may be executed in counterparts, each of which will be deemed an original with all such counterparts together constituting one instrument.

 

IN WITNESS WHEREOF the parties have caused this Amendment No. 3 to be executed by their respective duly authorized officers, and have duly delivered and executed this Amendment No. 3 under seal as of the Amendment Date.

 

 

	
RADIUS   HEALTH, INC.
    	
NORDIC BIOSCIENCE CLINICAL   DEVELOPMENT VII A/S
    
	
 
    	
 
    
	
 
    	
 
    
	
/s/ Gregory   Williams
    	
 
    	
/s/ Jeppe   Ragnar Andersen
    
	
By: Gregory Williams
    	
By: Jeppe Ragnar   Andersen
    
	
Title: Chief   Development Officer
    	
Title: CEO
    
	
 
    	
 
    
	
Notice Address
    	
Notice Address
    
	
Radius   Health, Inc.
    	
Nordic Bioscience   Clinical Development VII A/S
    
	
950 Winter Street
    	
Herlev Hovedgade 207
    
	
Waltham, MA 02451
    	
2730 Herlev
    
	
USA
    	
Denmark
    
	
Attn:   President & CEO
    	
Attn: CEO
    
	
Phone: 01.617.551.4700
    	
Phone: 45.4452.5251
    
	
Fax: 01.617.551.4701
    	
Fax: 45.4452.7765
    
			

 

1Exhibit 10.33

Exhibit 10.33

AMENDMENT TO
WINDSTREAM 2006 EQUITY INCENTIVE PLAN

WHEREAS, Windstream Holdings, Inc. (the “Company”) maintains the Windstream 2006 Equity Incentive Plan (as amended and restated effective February 12, 2014) (the “Plan”); and
WHEREAS, on April 24, 2015 the Company completed a separation of certain network and property assets from the Company’s business (the “Spin-Off”); and
WHEREAS, on April 26, 2015 a reverse stock split occurred following the Spin-Off so that each share of WHI Common Stock issued and outstanding (including shares of restricted stock and shares held in the Company's treasury, if any), shall, without any further action by the Company or any holder of shares of WHI Common Stock, be reclassified and become one-sixth (1/6) of a share of WHI Common Stock (the “Reverse Split”); and

WHEREAS, on  May 6, 2015, the Board of Directors of the Company, in their good faith discretion, approved an equitable adjustment to the number of shares of Company Common Stock under the plan by  multiplying the applicable number of shares of WHI Common Stock by a ratio of 4.16 which ratio was derived by dividing x by y, where x is the price of WHI Common Stock on April 24, 2015 and y is the average of the closing prices of WHI Common Stock on the 5 day period beginning on April 27, 2015 (with such prices adjusted for comparability to eliminate the effect of the Reverse Split and with the product rounded down to the nearest whole share).

NOW THEREFORE, BE IT RESOLVED, that effective as of May 4, 2015, the Company hereby amends the Plan in the respects hereinafter set forth:
		
	1.
	Section 3(a) of the Plan is hereby amended to read as follows:

(a) Subject to adjustment as provided in Section 12 of this Plan, the number of Common Shares that may be issued or transferred (i) upon the exercise of Option Rights or Appreciation Rights, (ii) as Restricted Shares, (iii) in payment of Restricted Stock Units, (iv) in payment of Performance Units or Performance Shares that have been earned, (v) as awards to Non-Employee Directors, (vi) in payment of awards granted under Section 10 of this Plan or (vii) in payment of dividend equivalents paid with respect to awards made under the Plan shall not exceed in the aggregate 24,266,666 Common Shares, plus any shares relating to awards that expire or are forfeited or are cancelled.  Common Shares covered by an award granted under the Plan shall not be counted as used unless and until they are actually issued and delivered to a Participant.  Without limiting the generality of the foregoing, upon payment in cash of the benefit provided by any award granted under the Plan, any Common Shares that were covered by that award will be available for issue or transfer hereunder.  Notwithstanding anything to the contrary contained herein: (A) Common Shares tendered in payment of the Option Price of an Option Right shall not be added to the aggregate Plan limit described above; (B) Common Shares withheld by the Company to satisfy the tax withholding obligation shall not be added to the aggregate Plan limit described above; (C) Common Shares that are repurchased by the 

Company with Option Right proceeds shall not be added to the aggregate Plan limit described above; and (D) all Common Shares covered by an Appreciation Right, to the extent that it is exercised and settled in Common Shares, and whether or not Common Shares are actually issued to the Participant upon exercise of the right, shall be considered issued or transferred pursuant to the Plan.  Such Common Shares may be shares of original issuance or treasury shares or a combination of the foregoing. 

		
	2.
	Section 3(c) of the Plan is hereby amended to read as follows:

(c)  Notwithstanding anything in this Section 3, or elsewhere in this Plan, to the contrary and subject to adjustment as provided in Section 12 of this Plan, (i) the aggregate number of Common Shares actually issued or transferred by the Company upon the exercise of Incentive Stock Options shall not exceed 6,933,333 Common Shares; and (ii) no Participant shall be granted Option Rights and Appreciation Rights, in the aggregate, for more than 693,333 Common Shares during any calendar year.
		
	4.
	Section 3(d) of the Plan is hereby amended to read as follows:

(d)  Notwithstanding any other provision of this Plan to the contrary, in no event shall any Participant in any calendar year receive an award of (i) Performance Shares, Restricted Shares or Restricted Stock Units that specify Management Objectives, in the aggregate for more than 693,333 Common Shares or (ii) Performance Units having an aggregate maximum value as of their respective Dates of Grant in excess of $12,000,000.
		
	5.
	Except as explicitly set forth herein, the Plan will remain in full force and effect.

                    	
		
	 
	 

	WINDSTREAM HOLDINGS, INC.

	 
	 

	By:
	/s/John P. Fletcher

	 
	John P. Fletcher, EVP and General CounselExhibit 10.34

Exhibit 10.34

AMENDMENT TO
PAETEC HOLDING CORP. 
2011 AMENDED AND RESTATED OMNIBUS INCENTIVE PLAN

WHEREAS, Windstream Holdings, Inc. (the “Company”) maintains the PAETEC Holding Corp. 2011 Amended and Restated Omnibus Incentive Plan (the “Plan”); and
WHEREAS, on April 24, 2015 the Company completed a separation of certain network and property assets from the Company’s business (the “Spin-Off”); and
WHEREAS, on April 26, 2015 a reverse stock split occurred following the Spin-Off so that each share of WHI Common Stock issued and outstanding (including shares of restricted stock and shares held in the Company's treasury, if any), shall, without any further action by the Company or any holder of shares of WHI Common Stock, be reclassified and become one-sixth (1/6) of a share of WHI Common Stock (the “Reverse Split”); and
WHEREAS, on  May 6, 2015, the Board of Directors of the Company, in their good faith discretion, approved an equitable adjustment to the number of shares of Company Common Stock under the plan by  multiplying the applicable number of shares of WHI Common Stock by a ratio of 4.16, which ratio was derived by dividing x by y, where x is the price of WHI Common Stock on April 24, 2015 and y is the average of the closing prices of WHI Common Stock on the 5 day period beginning on April 27, 2015 (with such prices adjusted for comparability to eliminate the effect of the Reverse Split and with the product rounded down to the nearest whole share).
NOW THEREFORE, BE IT RESOLVED, that effective as of May 4, 2015, the Company hereby amends the Plan in the respects hereinafter set forth:
		
	1.
	All references in the Plan to Windstream Corporation are hereby amended to be references to Windstream Holdings, Inc., except where the context clearly dictates otherwise.

		
	2.
	Section 4.1 of the Plan is hereby amended to read as follows:

“Subject to other provisions of this Section 4 and subject to adjustment as provided under the Plan, the total number of shares of Stock that shall be authorized for issuance for Awards under the Plan shall be equal to the sum of (x) 3,827,200 shares of Stock plus (y) the number of shares of Stock available for future awards under the Prior Plan as of the Effective Date, multiplied by the Exchange Ratio, as defined in the Merger Agreement, plus (z) the number of shares of Stock related to awards outstanding under the Prior Plan as of the Effective Date, as adjusted pursuant to the Merger Agreement, which thereafter terminate by expiration, forfeiture, cancellation, or otherwise without the issuance of such shares.  Such shares of Stock may be authorized and unissued shares of Stock or treasury shares of Stock or any combination of the foregoing, as may be determined from time to time by the Board or by the Committee.  Any of the shares of Stock available for issuance under the Plan may be used for any type of Award under the Plan, and any or all of the shares of Stock available for issuance under the Plan shall be available for issuance pursuant to Incentive Stock Options. 

		
	3.
	Section 6.2(a) of the Plan is hereby amended to read as follows:

(a)  the maximum number of shares of Stock subject to Options or SARs that may be granted under the Plan in a calendar year to any person eligible for an Award under Section 6 is 1,275,733 shares; provided that the maximum number of shares of Stock subject to Options or SARs that may be granted under the Plan to any person eligible for an Award under Section 6 in the year in which such person is first employed by, or first provides other Service to the Company or any Affiliate is 1,913,600 shares.
		
	4.
	Section 6.2(b) of the Plan is hereby amended to read as follows:

(b)  the maximum number of shares of Stock that may be granted under the Plan, other than pursuant to Options of SARs in a calendar year to any person eligible for an Award under Section 6 is 318,933 shares; provided that the maximum number of shares of Stock subject to Awards other than Options or SARS that may be granted under the Plan to any person eligible for an Award under Section 6 in the year in which such person is first employed by, or first provides other Service to, the Company or any Affiliate is 478,400 shares; and
5.    Except as explicitly set forth herein, the Plan will remain in full force and effect.
           	
		
	 
	 

	WINDSTREAM HOLDINGS, INC.

	 
	 

	By:
	/s/John P. Fletcher

	 
	John P. Fletcher, EVP and General Counsel

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