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                                                                    EXHIBIT 10.1

                          MOMENTA PHARMACEUTICALS, INC.

                            2002 STOCK INCENTIVE PLAN

               (AMENDED AND RESTATED PLAN AS OF DECEMBER 18, 2002)

     1. PURPOSE. The purpose of this plan (the "Plan") is to secure for Momenta
Pharmaceuticals, a Delaware corporation (the "Company"), and its shareholders
the benefits arising from capital stock ownership by employees, officers and
directors of, and consultants or advisors to, the Company and its parent and
subsidiary corporations who are expected to contribute to the Company's future
growth and success. Under the Plan recipients may be awarded both (i) Options
(as defined in Section 2.1) to purchase the Company's common stock, par value
$.0001 per share ("Common Stock") and (ii) shares of the Company's Common Stock
("Restricted Stock Awards"). Except where the context otherwise requires, the
term "Company" shall include the parent and all present and future subsidiaries
of the Company as defined in Sections 424(e) and 424(f) of the Internal Revenue
Code of 1986, as amended or replaced from time to time (the "Code"). Those
provisions of the Plan which make express reference to Section 422 shall apply
only to Incentive Stock Options (as that term is defined in the Plan).

     2. TYPES OF AWARDS AND ADMINISTRATION.

         2.1 OPTIONS. Options granted pursuant to the Plan ("Options")
shall be authorized by action of the Board of Directors of the Company and may
be either incentive stock options ("Incentive Stock Options") meeting the
requirements of Section 422 of the Code or non-statutory Options which are not
intended to meet the requirements of Section 422 of the Code. All Options when
granted are intended to be non-statutory Options, unless the applicable Option
Agreement (as defined in Section 5.1) explicitly states that the Option is
intended to be an Incentive Stock Option. If an Option is intended to be an
Incentive Stock Option, and if for any reason such Option (or any portion
thereof) shall not qualify as an Incentive Stock Option, then, to the extent of
such nonqualification, such Option (or portion thereof) shall be regarded as a
non-statutory Option appropriately granted under the Plan provided that such
Option (or portion thereof) otherwise meets the Plan's requirements relating to
non-statutory Options. The vesting of Options may be conditioned upon the
completion of a specified period of employment with the Company and/or such
other conditions or events as the Board may determine. The Board may also
provide that Options are immediately exercisable subject to certain repurchase
rights in the Company dependent upon the continued employment of the optionee
and/or such other conditions or event as the Board may determine.

         2.2 RESTRICTED STOCK AWARDS. The Board in its discretion may
grant Restricted Stock Awards, entitling the recipient to acquire, for a
purchase price determined by the Board, shares of Common Stock subject to such
restrictions and conditions as the Board may determine at the time of grant
("Restricted Stock"), including continued employment and/or achievement of
pre-established performance goals and objectives.

         2.3 ADMINISTRATION. The Plan shall be administered by the Board
of Directors of the Company, whose construction and interpretation of the terms
and provisions of the Plan shall be final and conclusive. The Board of Directors
may in its sole discretion issue Restricted Stock

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and grant Options to purchase shares of Common Stock, and issue shares upon
exercise of such Options as provided in the Plan. The Board shall have
authority, subject to the express provisions of the Plan, to construe the
respective Restricted Stock Agreements (as defined in Section 5.2), Option
Agreements and the Plan, to prescribe, amend and rescind rules and regulations
relating to the Plan, to determine the terms and provisions of the respective
Restricted Stock Agreements and Option Agreements, and to make all other
determinations in the judgment of the Board of Directors necessary or desirable
for the administration of the Plan. The Board of Directors may correct any
defect or supply any omission or reconcile any inconsistency in the Plan or in
any Restricted Stock Agreement or Option Agreement in the manner and to the
extent it shall deem expedient to carry the Plan into effect and it shall be the
sole and final judge of such expediency. No director or person acting pursuant
to authority delegated by the Board of Directors shall be liable for any action
or determination under the Plan made in good faith. The Board of Directors may,
to the full extent permitted by or consistent with applicable laws or
regulations (including, without limitation, applicable state law), delegate any
or all of its powers under the Plan to a committee (the "Committee") appointed
by the Board of Directors, and if the Committee is so appointed all references
to the Board of Directors in the Plan shall mean and relate to such Committee.

     3. ELIGIBILITY. Options may be granted, and Restricted Stock may be issued,
to persons who are, at the time of such grant or issuance, employees, officers
or directors of, or consultants or advisors to, the Company; PROVIDED, that the
class of persons to whom Incentive Stock Options may be granted shall be limited
to employees of the Company.

     4. STOCK SUBJECT TO PLAN. Subject to adjustment as provided in Section 14
below, the maximum number of shares of Common Stock of the Company which may be
issued under the Plan is 1,028,662 shares. If an Option shall expire or
terminate for any reason without having been exercised in full, the unpurchased
shares subject to such Option shall again be available for subsequent Option
grants under the Plan. If shares of Restricted Stock shall be forfeited to, or
otherwise repurchased by, the Company pursuant to a Restricted Stock Agreement,
such purchased shares shall again be available for subsequent Option grants or
Restricted Stock Awards under the Plan. If shares issued upon exercise of an
Option are tendered to the Company in payment of the exercise price of an
Option, such tendered shares shall again be available for subsequent Option
grants under the Plan.

     5. FORMS OF RESTRICTED STOCK AGREEMENTS AND OPTION AGREEMENTS.

         5.1 OPTION AGREEMENT. As a condition to the grant of an Option, each
recipient of an Option shall execute an option agreement ("Option Agreement") in
such form not inconsistent with the Plan as may be approved by the Board of
Directors. Such Option Agreements may differ among recipients.

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         5.2 RESTRICTED STOCK AGREEMENT. As a condition to the issuance of
Restricted Stock, each recipient thereof shall execute an agreement ("Restricted
Stock Agreement") in such form not inconsistent with the Plan as may be approved
by the Board of Directors. Such Restricted Stock Agreements may differ among
recipients and need not be entitled "Restricted Stock Agreements."

         5.3 "STAND-OFF" AGREEMENT. Unless the Board of Directors specifies
otherwise, each Restricted Stock Agreement and each Option Agreement shall
provide that the holder of any Option or the purchaser of any Restricted Stock
agrees (i) for a period of 180 days from the effective date of any registration
of securities of the Company in connection with an underwritten public offering
under the Securities Act of 1933, as amended (the "Securities Act"), not to
sell, make any short sale of, loan, grant any option for the purchase of, or
otherwise dispose of any shares of the Company's common stock owned or
controlled by him (other than those shares permitted to be included in the
offering), without the prior written consent of the Company or the underwriters
managing such offering, and (ii) to execute any agreement reflecting clause (i)
above as may be requested by the Company or the managing underwriters at the
time of such offering.

         5.4 RIGHT OF FIRST REFUSAL. Unless the Board of Directors specifies
otherwise, each Restricted Stock Agreement and each Option Agreement shall
provide that the Company shall have a right of first refusal with respect to the
transfer or proposed transfer of any Restricted Stock (whether or not subject to
vesting limitations) or shares issued upon exercise of any Option granted
hereunder.

     6. PURCHASE PRICE.

         6.1 GENERAL. The purchase price per share of Restricted Stock and per
share of stock deliverable upon the exercise of an Option shall be determined by
the Board of Directors, PROVIDED, HOWEVER, that in the case of an Incentive
Stock Option, the exercise price shall not be less than 100% of the fair market
value of such stock, as determined by the Board of Directors, at the time of
grant of such Option, or less than 110% of such fair market value in the case of
Options described in Section 11.2.

         6.2 PAYMENT OF PURCHASE PRICE. Option Agreements may provide for the
payment of the exercise price by delivery of cash or a check to the order of the
Company in an amount equal to the exercise price of such Options, or, to the
extent provided in the applicable Option Agreement, (i) by delivery to the
Company of shares of Common Stock of the Company already owned by the optionee
for a period of six months and having a fair market value equal in amount to the
exercise price of the Options being exercised, (ii) a personal recourse note
issued by the optionee to the Company in a principal amount equal to such
aggregate exercise price and with such other terms, including interest rate and
maturity, as the Company may determine in its discretion; PROVIDED, HOWEVER,
that the interest rate borne by such note shall not be less than the lowest
applicable federal rate, as defined in Section 1274(d) of the Code, (iii) by any
other means which the Board of Directors determines are consistent with the
purpose of the Plan and with applicable laws and regulations or (iv) by any
combination of such methods of payment. The fair market value of any shares of
the Company's Common Stock or other non-cash

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consideration which may be delivered upon exercise of an Option shall be
determined by the Board of Directors. Restricted Stock Agreements may provide
for the payment of any purchase price in any manner approved by the Board of
Directors at the time of authorizing the issuance thereof.

     7. OPTION PERIOD. Each Option and all rights thereunder shall expire on
such date as shall be set forth in the applicable Option Agreement, PROVIDED
THAT, in any event, in the case of an Incentive Stock Option, such date shall
not be later than 10 years after the date on which the Option is granted (or
five years in the case of Options described in Section 11.2), and, in the case
of non-statutory Options, not later than 10 years after the date on which the
Option is granted, and, in either case, shall be subject to earlier termination
as provided in the Plan.

     8. EXERCISE OF OPTIONS. Each Option shall be exercisable either in full or
in installments at such time or times and during such period as shall be set
forth in the agreement evidencing such Option, subject to the provisions of the
Plan.

     9. NONTRANSFERABILITY OF OPTIONS. No Option shall be assignable or
transferable by the person to whom it is granted, either voluntarily or by
operation of law, except by will or the laws of descent and distribution. During
the life an optionee, an Option held by him or her shall be exercisable only by
the optionee.

     10. EFFECT OF TERMINATION. No Incentive Stock Option may be exercised
unless, at the time of such exercise, the optionee is, and has continuously
since the date of grant of his or her Incentive Stock Option been, employed by
the Company, except that, unless the Option Agreement or instrument expressly
provides otherwise:

         10.1 the Incentive Stock Option may be exercised within the period of
thirty days (or within such lesser period as may be specified in the applicable
Option Agreement) after the date the optionee's employment with the Company
terminates other than for death, disability or termination for Cause;

         10.2 if the optionee dies while in the employ of the Company, the
Incentive Stock Option may be exercised by the person to whom it is transferred
by will or the laws of descent and distribution within the period of one hundred
and eighty days after the date of death (or within such lesser period as may be
specified in the applicable Option Agreement);

         10.3 if the optionee becomes disabled (within the meaning of Section
22(e)(3) of the Code or any successor provision thereto) while in the employ of
the Company, the Incentive Stock Option may be exercised within the period of
one hundred and eighty days after the date the optionee ceases to be such an
employee because of such disability (or within such lesser period as may be
specified in the applicable Option Agreement); and

         10.4 if the optionee's employment with the Company is terminated by the
Company for Cause, the Incentive Stock Option shall terminate immediately. The
term "Cause" shall mean (a) any breach by the optionee of any agreement to which
the optionee and the Company are both parties (including, without limitation,
breach by the optionee of any provision of any employment, consulting, advisory,
nondisclosure, non-competition or other similar agreement), (b) any act (other
than retirement) or omission to act by the optionee which may have a material

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and adverse effect on the Company's business or on the optionee's ability to
perform services for the Company, including, without limitation, the commission
of any crime (other than minor traffic violations), or (c) any material
misconduct or material neglect of duties by the optionee in connection with the
business or affairs of the Company or any parent, subsidiary or affiliate of the
Company. The optionee shall be considered to have been discharged for Cause if
the Company determines, within 30 days after the optionee's resignation, that
discharge for Cause was warranted. The Board shall have sole authority and
discretion to determine whether the optionee's employment has been terminated
for Cause;

PROVIDED, HOWEVER, that in no event may any Incentive Stock Option be exercised
after the expiration date of the Incentive Stock Option. For all purposes of the
Plan and any Incentive Stock Option granted hereunder, "employment" shall be
defined in accordance with the provisions of Section 1.421-7(h) of the Income
Tax Regulations (or any successor regulations).

     A non-statutory Option granted to an employee shall be subject to the
foregoing provisions of this Section 10 as if it were an Incentive Stock Option,
but a non-statutory Option may also be exercised so long as the optionee
maintains a relationship with the Company as a director, consultant or adviser,
unless the Option Agreement provides otherwise.

     11. INCENTIVE STOCK OPTIONS. Options which are intended to be Incentive
Stock Options shall be subject to the following additional terms and conditions:

         11.1 EXPRESS DESIGNATION. All Incentive Stock Options shall, at the
time of grant, be specifically designated as such in the Option Agreement
covering such Incentive Stock Options.

         11.2 10% SHAREHOLDER. If any employee to whom an Incentive Stock Option
is to be granted is, at the time of the grant of such Option, the owner of stock
possessing more than 10% of the total combined voting power of all classes of
stock of the Company (after taking into account the attribution of stock
ownership rules of Section 424(d) of the Code), then the following special
provisions shall be applicable to the Incentive Stock Option granted to such
individual:

               11.2.1 the purchase price per share of the Common Stock subject
to such Incentive Stock Option shall not be less than 110% of the fair market
value of one share of Common Stock at the time of grant; and

               11.2.2 the option exercise period shall not exceed five years
from the date of grant.

     11.3 DOLLAR LIMITATION. For so long as the Code shall so provide, Options
granted to any employee under the Plan (and any other incentive stock option
plans of the Company) which are intended to constitute Incentive Stock Options
shall not constitute Incentive Stock Options to the extent that such Options, in
the aggregate, become exercisable for the first time in any one calendar year
for shares of Common Stock with an aggregate fair market value (determined as of
the respective date or dates of grant) of more than $100,000.

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     12. ADDITIONAL PROVISIONS.

         12.1 ADDITIONAL PROVISIONS. The Board of Directors may, in its sole
discretion, include additional provisions in Restricted Stock Agreements and
Option Agreements, including, without limitation, restrictions on transfer,
rights of the Company to repurchase shares of Restricted Stock or shares of
Common Stock acquired upon exercise of Options, commitments to pay cash bonuses,
to make, arrange for or guaranty loans or to transfer other property to
optionees upon exercise of Options, or such other provisions as shall be
determined by the Board of Directors; PROVIDED THAT such additional provisions
shall not be inconsistent with any other term or condition of the Plan and such
additional provisions shall not be such as to cause any Incentive Stock Option
to fail to qualify as an Incentive Stock Option within the meaning of Section
422 of the Code.

         12.2 ACCELERATION, EXTENSION, ETC. The Board of Directors may, in its
sole discretion, (i) accelerate the date or dates on which all or any particular
Option or Options may be exercised or (ii) extend the dates during which all, or
any particular, Option or Options may be exercised.

     13. RIGHTS AS A SHAREHOLDER. The holder of an Option shall have no rights
as a shareholder with respect to any shares covered by the Option (including,
without limitation, any rights to receive dividends or non-cash distributions
with respect to such shares) until the date of issue of a stock certificate to
him or her for such shares. No adjustment shall be made for dividends or other
rights for which the record date is prior to the date such stock certificate is
issued.

     14. ADJUSTMENT PROVISIONS FOR RECAPITALIZATIONS AND RELATED TRANSACTIONS.

         14.1 GENERAL. If, through or as a result of any merger, consolidation,
sale of all or substantially all of the assets of the Company, reorganization,
recapitalization, reclassification, stock dividend, stock split, reverse stock
split or other similar transaction, (i) the outstanding shares of Common Stock
are increased, decreased or exchanged for a different number or kind of shares
or other securities of the Company, or (ii) additional shares or new or
different shares or other securities of the Company or other non-cash assets are
distributed with respect to such shares of Common Stock or other securities, an
appropriate and proportionate adjustment may be made in (x) the maximum number
and kind of shares reserved for issuance under the Plan, (y) the number and kind
of shares or other securities subject to any then outstanding Options, and (z)
the price for each share subject to any then outstanding Options, without
changing the aggregate purchase price as to which such Options remain
exercisable. Notwithstanding the foregoing, no adjustment shall be made pursuant
to this Section 14 if such adjustment would cause the Plan to fail to comply
with Section 422 of the Code.

         14.2 BOARD AUTHORITY TO MAKE ADJUSTMENTS. Any adjustments under this
Section 14 will be made by the Board of Directors, whose determination as to
what adjustments, if any, will be made and the extent thereof will be final,
binding and conclusive. No fractional shares will be issued under the Plan on
account of any such adjustments.

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     15. MERGER, CONSOLIDATION, ASSET SALE, LIQUIDATION, ETC.

         15.1 GENERAL. In the event of a consolidation or merger or sale of all
or substantially all of the assets of the Company in which outstanding shares of
Common Stock are exchanged for securities, cash or other property of any other
corporation or business entity, or in the event of a liquidation of the Company,
the Board of Directors of the Company, or the board of directors of any
corporation assuming the obligations of the Company, may, in its discretion,
take any one or more of the following actions, as to some or all outstanding
Options (and need not take the same action as to each such Option): (i) provide
that such Options shall be assumed, or equivalent Options shall be substituted,
by the acquiring or succeeding corporation (or an affiliate thereof), PROVIDED
THAT any such Options substituted for Incentive Stock Options shall meet the
requirements of Section 424(a) of the Code, (ii) upon written notice to the
optionees, provide that all unexercised Options will terminate immediately prior
to the consummation of such transaction unless exercised by the optionee (to the
extent otherwise then exercisable) within a specified period following the date
of such notice, (iii) in the event of a merger under the terms of which holders
of the Common Stock of the Company will receive upon consummation thereof a cash
payment for each share surrendered in the merger (the "Merger Price"), make or
provide for a cash payment to the optionees equal to the difference between (A)
the Merger Price times the number of shares of Common Stock subject to such
outstanding Options (to the extent then exercisable at prices not in excess of
the Merger Price) and (B) the aggregate exercise price of all such outstanding
Options, in exchange for the termination of such Options, and (iv) provide that
all or any outstanding Options shall become exercisable in full immediately
prior to such event.

         15.2 SUBSTITUTE OPTIONS. The Company may grant Options in substitution
for Options held by employees of another corporation who become employees of the
Company, or a subsidiary of the Company, as the result of a merger or
consolidation of the employing corporation with the Company or a subsidiary of
the Company, or as a result of the acquisition by the Company, or one of its
subsidiaries, of property or stock of the employing corporation. The Company may
direct that substitute Options be granted on such terms and conditions as the
Board of Directors considers appropriate in the circumstances.

         15.3 RESTRICTED STOCK. In the event of a business combination or other
transaction of the type detailed in Section 15.1, any securities, cash or other
property received in exchange for shares of Restricted Stock shall continue to
be governed by the provisions of any Restricted Stock Agreement pursuant to
which they were issued, including any provision regarding vesting, and such
securities, cash, or other property may be held in escrow on such terms as the
Board of Directors may direct, to insure compliance with the terms of any such
Restricted Stock Agreement.

     16. NO SPECIAL EMPLOYMENT RIGHTS. Nothing contained in the Plan or in any
Option or Grant Stock Agreement shall confer upon any optionee any right with
respect to the continuation of his or her employment by the Company or interfere
in any way with the right of the Company at any time to terminate such
employment or to increase or decrease the compensation of the optionee.

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     17. OTHER EMPLOYEE BENEFITS. The amount of any compensation deemed to be
received by an employee as a result of the issuance of shares of Restricted
Stock or the grant or exercise of an Option or the sale of shares received upon
such award or exercise will not constitute compensation with respect to which
any other employee benefits of such employee are determined, including, without
limitation, benefits under any bonus, pension, profit-sharing, life insurance or
salary continuation plan, except as otherwise specifically determined by the
Board of Directors.

     18. AMENDMENT OF THE PLAN AND AWARDS.

         18.1 The Board of Directors may at any time, and from time to time,
modify or amend the Plan in any respect, except that if at any time the approval
of the shareholders of the Company is required under Section 422 of the Code or
any successor provision with respect to Incentive Stock Options, the Board of
Directors may not effect such modification or amendment without such approval.

         18.2 The Board of Directors may amend, modify or terminate any
outstanding Option or Restricted Stock Award, including but not limited to,
substituting therefore another Option or Restricted Stock Award of the same or a
different type, changing the date of exercise or realization, and converting an
Incentive Stock Option to a Nonstatutory Stock Option, provided that such
holder's or purchaser's consent to such action shall be required unless the
Board of Directors determines that the action, taking into account any related
action, would not materially and adversely affect such holder or purchaser.

         18.3 The Board of Directors shall have the right to amend or modify the
terms and provisions of the Plan and of any outstanding Incentive Stock Options
to the extent necessary to qualify any or all such Options for such favorable
federal income tax treatment (including deferral of taxation upon exercise) as
may be afforded incentive stock options under Section 422 of the Code.

     19. WITHHOLDING. The Company shall have the right to deduct from payments
of any kind otherwise due to the optionee any federal, state or local taxes of
any kind required by law to be withheld with respect to issuance of any shares
of Restricted Stock or shares issued upon exercise of Options. Subject to the
prior approval of the Company, which may be withheld by the Company in its sole
discretion, the obligor may elect to satisfy such minimum withholding
obligations, in whole or in part, (i) by causing the Company to withhold shares
of Common Stock otherwise issuable or (ii) by delivering to the Company shares
of Common Stock already owned by the obligor for a period of at least six
months. The shares so delivered or withheld shall have a fair market value equal
to such withholding obligation. The fair market value of the shares used to
satisfy such withholding obligation shall be determined by the Company as of the
date that the amount of tax to be withheld is to be determined. A person who has
made an election pursuant to this Section 19 may only satisfy his or her
withholding obligation with shares of Common Stock which are not subject to any
repurchase, forfeiture, unfulfilled vesting or other similar requirements.

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     20. EFFECTIVE DATE AND DURATION OF THE PLAN.

         20.1 EFFECTIVE DATE. The Plan shall become effective when adopted by
the Board of Directors, but no Incentive Stock Option shall become exercisable
unless and until the Plan shall have been approved by the Company's
shareholders. If such shareholder approval is not obtained within twelve months
after the date of the Board's adoption of the Plan, no Options previously
granted under the Plan shall be deemed to be Incentive Stock Options and no
Incentive Stock Options shall be granted thereafter. Amendments to the Plan not
requiring shareholder approval shall become effective when adopted by the Board
of Directors; amendments requiring shareholder approval (as provided in Section
18) shall become effective when adopted by the Board of Directors, but no
Incentive Stock Option granted after the date of such amendment shall become
exercisable (to the extent that such amendment to the Plan was required to
enable the Company to grant such Incentive Stock Option to a particular
optionee) unless and until such amendment shall have been approved by the
Company's shareholders. If such shareholder approval is not obtained within
twelve months of the Board's adoption of such amendment, any Incentive Stock
Options granted on or after the date of such amendment shall terminate to the
extent that such amendment to the Plan was required to enable the Company to
grant such Option to a particular optionee. Subject to this limitation, Options
may be granted under the Plan at any time after the effective date and before
the date fixed for termination of the Plan.

         20.2 TERMINATION. Unless sooner terminated in accordance with Section
15 or by the Board of Directors, the Plan shall terminate upon the close of
business on the day next preceding the tenth anniversary of the date of its
adoption by the Board of Directors.

     21. PROVISION FOR FOREIGN PARTICIPANTS. The Board of Directors may, without
amending the Plan, modify the terms of Option or Grant Stock Agreements to
differ from those specified in the Plan with respect to participants who are
foreign nationals or employed outside the United States to recognize differences
in laws, rules, regulations or customs of such foreign jurisdictions with
respect to tax, securities, currency, employee benefit or other matters.

     22. REQUIREMENTS OF LAW. The Company shall not be required to sell or issue
any shares under any Option if the issuance of such shares shall constitute a
violation by the optionee or by the Company of any provisions of any law or
regulation of any governmental authority. In addition, in connection with the
Securities Act, the Company shall not be required to issue any shares upon
exercise of any Option unless the Company has received evidence satisfactory to
it to the effect that the holder of such Option will not transfer such shares
except pursuant to a registration statement in effect under the Act or unless an
opinion of counsel satisfactory to the Company has been received by the Company
to the effect that such registration is not required in connection with any such
transfer. Any determination in this connection by the Board shall be final,
binding and conclusive. In the event the shares issuable on exercise of an
Option are not registered under the Act or under the securities laws of each
relevant state or other jurisdiction, the Company may imprint on the
certificate(s) appropriate legends that counsel for the Company considers
necessary or advisable to comply with the Act or any such state or other
securities law. The Company may register, but in no event shall be obligated to
register, any securities covered by the Plan pursuant to the Act; and in the
event any shares are so registered the Company may remove any legend on
certificates representing such shares. The Company shall not be obligated

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to take any affirmative action in order to cause the exercise of an Option or
the issuance of shares pursuant thereto to comply with any law or regulation of
any governmental authority.

     23. GOVERNING LAW. This Plan and each Option shall be governed by the laws
of the Commonwealth of Massachusetts, without regard to its principles of
conflicts of law.

                                      * * *

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                                                                    EXHIBIT 10.4

                                                                  EXECUTION COPY

                CONFIDENTIAL MATERIALS OMITTED AND FILED WITH THE
      SECURITIES AND EXCHANGE COMMISSION. ASTERISKS DENOTE SUCH OMISSIONS.

                       COLLABORATION AND LICENSE AGREEMENT

                                  BY AND AMONG

                          MOMENTA PHARMACEUTICALS, INC.

                                       AND

                           BIOCHEMIE WEST INDIES, N.V.

                                       AND

                          GENEVA PHARMACEUTICALS, INC.

                         ------------------------------

                                NOVEMBER 1, 2003

<Page>

                                                                  EXECUTION COPY

                                TABLE OF CONTENTS

<Table>
<Caption>
                                                                              Page
                                                                              ----
<S>                                                                              <C>
1.   DEFINITIONS.................................................................1
     1.1.    "Additional Costs Amount"...........................................1
     1.2.    "Affiliate".........................................................1
     1.3.    "ANDA"..............................................................2
     1.4.    "ANDA Final Approval"...............................................2
     1.5.    "Annual Collaboration Plan".........................................2
     1.6.    "Aventis"...........................................................2
     1.7.    "Aventis [**]"......................................................2
     1.8.    "Business Day"......................................................2
     1.9.    "Capped Costs"......................................................2
     1.10.   "cGMP"..............................................................3
     1.11.   "Characterize"......................................................3
     1.12.   "Collaboration Know-How"............................................3
     1.13.   "Collaborative Program".............................................3
     1.14.   "Commercial Third Party"............................................3
     1.15.   "Commercialization," "Commercialize" or "Commercializing"...........3
     1.16.   "Commercialization Costs"...........................................3
     1.17.   "Commercially Reasonable Efforts"...................................3
     1.18.   "Confidential Information"..........................................4
     1.19.   "Contract Year".....................................................4
     1.20.   "Control" or "Controlled"...........................................4
     1.21.   "Develop" or "Development"..........................................4
     1.22.   "Development Costs".................................................5
     1.23.   "District Court Legal Clearance"....................................5
     1.24.   "Excess Costs"......................................................5
     1.25.   "Executive Officers"................................................5
     1.26.   "FDA"...............................................................6
     1.27.   "Field".............................................................6
     1.28.   "Final Legal Clearance".............................................6
     1.29.   "First Commercial Sale".............................................6
     1.30.   "Fragmin Opportunity"...............................................6
     1.31.   "FTE"...............................................................6
     1.32.   "FTE Rate"..........................................................6
     1.33.   "Improved Enoxaparin"...............................................6
     1.34.   "Improvement".......................................................6
     1.35.   "Joint Collaboration IP"............................................7
     1.36.   "Joint Collaboration Know-How"......................................7
     1.37.   "Joint Collaboration Patent Rights".................................7
     1.38.   "Joint Product-Specific Know-How"...................................7
     1.39.   "Joint Product-Specific Patent Rights"..............................7
     1.40.   "Know-How"..........................................................7
     1.41.   "Label".............................................................7
     1.42.   "Legal Activities"..................................................7
     1.43.   "Legal Clearance"...................................................7
     1.44.   "Legal Clearance Costs".............................................8
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     1.45.   "Legal Expenses"....................................................8
     1.46.   "Locked Manufacturing Process"......................................8
     1.47.   "Lovenox(R)-Equivalent Product".....................................8
     1.48.   "Manufacturing Costs"...............................................8
     1.49.   "Marketing Approval"................................................9
     1.50.   "M118 Opportunity"..................................................9
     1.51.   "MIT"...............................................................9
     1.52.   "MIT Agreement".....................................................9
     1.53.   "Momenta Collaboration Know-How"....................................9
     1.54.   "Momenta Collaboration Patent Rights"...............................9
     1.55.   "Momenta Indemnified Parties".......................................9
     1.56.   "Momenta IP"........................................................9
     1.57.   "Momenta Know-How"..................................................9
     1.58.   "Momenta Patent Rights"............................................10
     1.59.   "Momenta Product-Specific Know-How"................................10
     1.60.   "Momenta Product-Specific Patent Rights"...........................10
     1.61.   "Net Sales"........................................................10
     1.62.   "Non-Injectable or Improved Enoxaparin Opportunity"................11
     1.63.   "Non-Owning Party".................................................11
     1.64.   "Non-U.S. Territory"...............................................11
     1.65.   "Owning Party".....................................................11
     1.66.   "Owning Party's IP"................................................11
     1.67.   "Party"............................................................11
     1.68.   "Patent Litigation"................................................11
     1.69.   "Patent Right".....................................................12
     1.70.   "Person"...........................................................12
     1.71.   "Post-Launch Quarter"..............................................12
     1.72.   "Post-Launch Year".................................................12
     1.73.   "Pre Final Legal Clearance Launch".................................12
     1.74.   "Product"..........................................................12
     1.75.   "Product Liability Costs"..........................................12
     1.76.   "Product-Specific Patent Activities"...............................12
     1.77.   "Product-Specific Patent Costs"....................................12
     1.78.   "Product-Specific Patent Rights"...................................13
     1.79.   "Profits"..........................................................13
     1.80.   "Project Leader"...................................................13
     1.81.   "Quarter"..........................................................13
     1.82.   "Regulatory Authority".............................................13
     1.83.   "Sandoz Collaboration Know-How"....................................13
     1.84.   "Sandoz Collaboration Patent Rights"...............................13
     1.85.   "Sandoz Indemnified Parties".......................................13
     1.86.   "Sandoz IP"........................................................13
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     1.87.   "Sandoz Know-How"..................................................14
     1.88.   "Sandoz Patent Rights".............................................14
     1.89.   "Sandoz Product-Specific Know-How".................................14
     1.90.   "Sandoz Product-Specific Patent Rights"............................14
     1.91.   "Selling Expenses".................................................14
     1.92.   "Settlement".......................................................14
     1.93.   "Settlement Costs".................................................14
     1.94.   "Stability Studies"................................................14
     1.95.   "Supply Chain".....................................................14
     1.96.   "Third Party"......................................................15
     1.97.   "Third-Party Competitor"...........................................15
     1.98.   "Third Party Royalties"............................................15
     1.99.   "U.S. Launch"......................................................15
     1.100.  "U.S. Territory"...................................................15
     1.101.  Other Defined Terms................................................15
2.   GRANT OF RIGHTS............................................................18
     2.1.    Momenta License Grants.............................................18
     2.2.    Sandoz Parties License Grants......................................18
     2.3.    Exclusivity........................................................18
     2.4.    Retained Rights....................................................19
     2.5.    Third Party Licensor Rights........................................19
3.   ADDITIONAL RIGHTS..........................................................19
     3.1.    Fragmin Opportunity; Right of First Negotiation....................19
     3.2.    M118 Opportunity; Right of First Negotiation.......................20
     3.3.    Non-Injectable or Improved Enoxaparin Opportunities................21
     3.4.    Non-U.S. Territory Option..........................................23
     3.5.    Equity Investment..................................................26
     3.6.    Sandoz Affiliates..................................................26
4.   FINANCIAL PAYMENTS.........................................................27
     4.1.    Capped Costs.......................................................27
     4.2.    FTE Funding........................................................27
     4.3.    Excess Costs.......................................................27
     4.4.    Commercialization Costs............................................28
     4.5.    U.S. Profit Interest...............................................28
     4.6.    U.S. Post-[**] Royalty.............................................28
     4.7.    U.S. [**] Royalty..................................................28
     4.8.    Aventis [**].......................................................29
     4.9.    Allocation Between Periods.........................................29
     4.10.   Milestone Payments.................................................29
     4.11.   Payment/Accounting.................................................31
     4.12.   True-Up............................................................32
5.   JOINT DEVELOPMENT AND COMMERCIALIZATION....................................33
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     5.1.    Joint Collaboration................................................33
     5.2.    Joint Project Team.................................................33
     5.3.    JPT Responsibilities...............................................33
     5.4.    Joint Steering Committee...........................................33
     5.5.    JSC Administration.................................................34
     5.6.    JSC Meetings.......................................................34
     5.7.    JSC Responsibilities...............................................34
     5.8.    Annual Collaboration Plan..........................................35
     5.9.    Compliance with Laws...............................................35
     5.10.   Legal Clearance....................................................36
6.   COMMERCIALIZATION BY SANDOZ................................................36
     6.1.    Review and Oversight...............................................36
     6.2.    Pre Final Legal Clearance Launch...................................36
7.   REGULATORY MATTERS.........................................................36
     7.1.    Review and Oversight...............................................36
     7.2.    ANDA Filing........................................................36
     7.3.    Ownership Of The ANDAs.............................................37
     7.4.    ANDA Responsibility................................................37
     7.5.    Regulatory Interaction.............................................37
8.   INTELLECTUAL PROPERTY......................................................37
     8.1.    Ownership..........................................................37
     8.2.    Patent Prosecution.................................................38
     8.3.    Participation of other Persons.....................................39
     8.4.    Enforcement of Non-Product-Specific Patent Rights..................40
     8.5.    Claimed Infringement...............................................42
     8.6.    Patent Invalidity Claim............................................42
     8.7.    Joint Collaboration IP and Product-Specific Patent Rights..........42
     8.8.    Obligations to Licensors...........................................43
     8.9.    Patent Marking.....................................................43
9.   WARRANTIES.................................................................43
     9.1.    Representations and Warranties of the Parties......................43
     9.2.    Momenta Representations............................................45
     9.3.    Sandoz Parties Representations.....................................45
     9.4.    Covenant...........................................................45
     9.5.    No Reliance by Third Parties.......................................45
     9.6.    No Other Warranties................................................45
10.  CONFIDENTIALITY............................................................45
     10.1.   Prior Confidentiality Agreement....................................45
     10.2.   Confidential Information...........................................46
     10.3.   Nondisclosure of Confidential Information..........................46
     10.4.   Exceptions.........................................................46
     10.5.   Identification.....................................................47
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     10.6.   Equitable Relief...................................................48
     10.7.   Survival...........................................................48
11.  TERM & TERMINATION.........................................................48
     11.1.   Term...............................................................48
     11.2.   Termination For Cause..............................................48
     11.3.   Termination Due to Lack of Commercial Viability....................49
     11.4.   Sandoz Milestone Termination.......................................49
     11.5.   Excessive Cost Termination.........................................50
     11.6.   Effects of Termination.............................................51
     11.7.   Bankruptcy.........................................................54
     11.8.   Survival...........................................................55
     11.9.   Non-Exclusive Remedy...............................................55
12.  INDEMNIFICATION............................................................55
     12.1.   Sandoz Indemnification of Momenta..................................55
     12.2.   Momenta Indemnification of Sandoz..................................56
     12.3.   Procedure..........................................................56
     12.4.   Insurance..........................................................57
13.  DISPUTE RESOLUTION.........................................................57
     13.1.   First Level Resolution.............................................57
     13.2.   Negotiation Between Executives.....................................58
     13.3.   Legal Remedies.....................................................58
14.  ADDITIONAL PROVISIONS......................................................58
     14.1.   Entire Agreement...................................................58
     14.2.   Amendments and Waiver..............................................58
     14.3.   Assignment.........................................................59
     14.4.   Nature of Relationship.............................................59
     14.5.   Notices............................................................59
     14.6.   Governing Law......................................................60
     14.7.   Jury Waiver........................................................60
     14.8.   Counterparts; Facsimile Signature..................................60
     14.9.   Severability.......................................................60
     14.10.  Expenses...........................................................61
     14.11.  Further Actions and Documents......................................61
     14.12.  Use of Trade Names and Trademarks..................................61
     14.13.  Affiliates.........................................................61
     14.14.  Exports............................................................61
     14.15.  Force Majeure......................................................61
     14.16.  Non-Use of MIT Name................................................62
     14.17.  Headings...........................................................62
     14.18.  Key Person Life Insurance..........................................62
     14.19.  No Consequential Damages...........................................62
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Schedule 1.22 -     Pre-Existing Costs                                          65
Schedule 1.48   -   Calculation of Manufacturing Costs                          66
Schedule 1.58   -   Current Momenta Patent Rights                               67
Schedule 4.3    -   Adjustment Schedule                                         74
Schedule 5.8    -   Annual Collaboration Plan:  Preliminary List of Activities
                    and Assignment of lead responsibility to Party(ies)         83
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                                                     PRIVILEGED AND CONFIDENTIAL

                       COLLABORATION AND LICENSE AGREEMENT

        This Collaboration and License Agreement ("AGREEMENT") is entered into
as of this 1st day of November, 2003 ("EFFECTIVE DATE"), by and between Momenta
Pharmaceuticals, Inc., a Delaware corporation ("MOMENTA") with a principal place
of business at 43 Moulton Street, Cambridge, Massachusetts, USA 02138, Biochemie
West Indies, N.V., a Netherlands Antilles corporation ("BCWI") with a principal
place of business at Pietermaai 6A, Willemstad, Curacao, Netherlands Antilles,
and Geneva Pharmaceuticals, Inc., a Colorado corporation ("SANDOZ") with a
principal place of business at 506 Carnegie Center, Suite 400, Princeton, New
Jersey USA 08540 (Sandoz, collectively with BCWI, are the "SANDOZ PARTIES", and
individually, each is a "SANDOZ PARTY").

                                    RECITALS

        WHEREAS, Momenta is a biotechnology company with specific expertise in
enoxaparin and the science of complex sugars, polysaccharides, their structures,
their sequencing, and their characterization;

        WHEREAS, Momenta is the owner and/or licensee of the Momenta Patent
Rights and Momenta Know-How, each as defined hereinafter;

        WHEREAS, Sandoz has substantial knowledge and expertise in the research,
development, manufacture and sale of pharmaceuticals;

        WHEREAS, the Sandoz Parties are the owners and/or licensees of the
Sandoz Patent Rights and Sandoz Know-How, each as defined hereinafter;

        WHEREAS, the Sandoz Parties wish to collaborate with Momenta to develop
and commercialize the Product, as defined hereinafter, using the Momenta Patent
Rights and Momenta Know-How under the terms and conditions specified herein.

        NOW, THEREFORE, in consideration of the mutual promises and covenants
set forth, the Parties agree as follows:

1.      DEFINITIONS

        When used in this Agreement, each of the following terms shall have the
meanings set forth in this Article 1:

        1.1.    "ADDITIONAL COSTS AMOUNT". Additional Costs Amount means,
initially, [**] Dollars (U.S.$[**]), as may be increased pursuant to Section
11.5.2.

        1.2.    "AFFILIATE". Affiliate means any corporation, company,
partnership, joint venture and/or firm that controls, is controlled by, or is
under common control with a Person. For purposes of this Section 1.2, "CONTROL"
shall mean (a) in the case of corporate entities, direct or

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indirect ownership of at least fifty percent (50%) of the stock or shares having
the right to vote for the election of directors, and (b) in the case of
non-corporate entities, direct or indirect ownership of at least fifty percent
(50%) of the equity interest with the power to direct the management and
policies of such non-corporate entities. The Parties acknowledge that in the
case of certain entities organized under the laws of certain countries outside
the United States, the maximum percentage ownership permitted by law for a
foreign investor may be less than fifty percent (50%), and that in such case
such lower percentage shall be substituted in the preceding sentence, PROVIDED
THAT such foreign investor has the power to direct the management and policies
of such entity.

        1.3.    "ANDA". ANDA means any of the following: (a) an Abbreviated New
Drug Application filed with the FDA or any successor applications or procedures
seeking authorization and approval to manufacture, package, ship, and sell a
product in the U.S. Territory; (b) any other regulatory filing in the U.S.
Territory as mutually agreed by the Parties in the Collaborative Program,
including without limitation filings that are similar to filings under clause
(a), such as an NDA, supplemental NDA or an application pursuant to Section
505(b)(2) of the Federal Food, Drug, and Cosmetic Act (the "FD&C ACT"); and (c)
all supplements and amendments that may be filed with respect to the foregoing.

        1.4.    "ANDA FINAL APPROVAL". ANDA Final Approval means the granting by
the FDA of final Marketing Approval to Sandoz or any of its Affiliates for an
ANDA for a Lovenox(R)-Equivalent Product.

        1.5.    "ANNUAL COLLABORATION PLAN". Annual Collaboration Plan means the
Development, Commercialization and Legal Activities plan for the Collaborative
Program to be developed by the Joint Project Team and approved by the Joint
Steering Committee for each Contract Year.

        1.6.    "AVENTIS". Aventis means (a) Aventis Pharmaceuticals Inc., (b)
its Affiliates, (c) the licensees and distributors of Aventis Pharmaceuticals
Inc. or its Affiliates for a Lovenox(R)-Equivalent Product (the Persons
described in Sections 1.6(a), (b) and (c), collectively, the "AVENTIS PERSONS"),
and (d) the successors and assigns of any Aventis Persons with respect to any
rights to any Lovenox(R)-Equivalent Product.

        1.7.    "AVENTIS [**]". Aventis [**] means [**] Dollars (U.S.$[**]);
PROVIDED, HOWEVER, THAT, if the Aventis [**] begins on a day after the first day
of a Post-Launch Year, the Aventis [**] for the remainder of such Post-Launch
Year shall equal the product of (a) the number of days between (and including)
the date of such termination of the [**] until the end of such Post-Launch Year,
multiplied by (b) the quotient of (i) U.S.$[**] divided by (ii) 365.

        1.8.    "BUSINESS DAY". Business Day means any day that is not a
Saturday, Sunday or other day on which commercial banks located in the State of
New York are authorized or required to be closed.

        1.9.    "CAPPED COSTS". Capped Costs means collectively Development
Costs and Legal Expenses.

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        1.10.   "cGMP". cGMP means current good manufacturing practices as set
forth in Title 21, Parts 210 and 211 of the CFR, as established by FDA.

        1.11.   "CHARACTERIZE". Characterize and Characterization, with respect
to the Product, means chemical and physical characterization of the Product and
Lovenox(R) with sufficient specificity, and documentation thereof as is
necessary to establish to the satisfaction of the FDA that the active ingredient
of the Product is the same as that of Lovenox(R), as required by 21 U.S.C.
Section 355(j)(2)(A)(ii)(I).

        1.12.   "COLLABORATION KNOW-HOW". Collaboration Know-How means Sandoz
Collaboration Know-How, Joint Collaboration Know-How and Momenta Collaboration
Know-How.

        1.13.   "COLLABORATIVE PROGRAM". Collaborative Program means the joint
initiative to be undertaken by the Parties to Develop and Commercialize, and
conduct Legal Activities with respect to, the Product in the U.S. Territory
within the Field as described in Articles 5, 6 and 7 and in the Annual
Collaboration Plans.

        1.14.   "COMMERCIAL THIRD PARTY". Commercial Third Party means a Third
Party that is not (a) an academic or non-profit research institution or (b) a
hospital; PROVIDED THAT, should any such entity market or manufacture
pharmaceutical products, such entity shall be considered a Commercial Third
Party.

        1.15.   "COMMERCIALIZATION," "COMMERCIALIZE" or "COMMERCIALIZING".
Commercialization, Commercialize or Commercializing means any and all activities
directed to commercial manufacturing (including, without limitation, the
manufacture of commercial supply for distribution in the U.S. Territory and the
manufacture of commercial inventory), marketing, promoting, distributing,
importing and/or selling the Product. "COMMERCIALIZATION," "COMMERCIALIZE" or
"COMMERCIALIZING" does not include Development or Legal Activities.

        1.16.   "COMMERCIALIZATION COSTS". Commercialization Costs means all
costs incurred by the Sandoz Parties, Momenta or their Affiliates in connection
with Commercializing the Product for sale in the U.S. Territory pursuant to this
Agreement, including any capital investment with respect thereto.
Commercialization Costs do not include (a) [**] pursuant to the [**] (which
shall be the sole responsibility of Momenta), (b) [**], (c) [**], (d) [**] or
(e) [**].

        1.17.   "COMMERCIALLY REASONABLE EFFORTS". Commercially Reasonable
Efforts shall mean, with respect to the efforts to be expended by a Party with
respect to any objective, reasonable, diligent, good faith efforts to accomplish
such objective as such Party would normally use to accomplish a similar
objective under similar circumstances exercising reasonable business judgment,
it being understood and agreed that, with respect to the Development or
Commercialization of the Product or Legal Activities, such efforts shall be
substantially equivalent to those efforts and resources commonly used by such
Party for a product owned by it or to which it has rights, which product is at a
similar stage in its development or product life and is of similar market
potential, taking into account efficacy, safety, approved labeling, the
competitiveness of alternative products in the marketplace, the

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patent and other proprietary position of the Product, the likelihood of
regulatory approval given the regulatory structure involved, the profitability
of the Product, alternative products and other relevant factors commonly
considered in similar circumstances. It is anticipated that the level of effort
will change over time, reflecting changes in the status of the Product.

        1.18.   "CONFIDENTIAL INFORMATION". Confidential Information means all
Know-How or other confidential or proprietary information and materials (whether
or not patentable) regarding a Party's technology, products or business, which
is designated as confidential in writing by the disclosing Party, whether by
letter or by the use of an appropriate stamp or legend, prior to or at the time
any such Know-How or other information or material is disclosed by the
disclosing Party to the other Party. Notwithstanding the foregoing to the
contrary, Know-How or other information or material that is orally or visually
disclosed by a Party, or is disclosed in writing without an appropriate letter,
stamp or legend, shall constitute Confidential Information of a Party (a) for
thirty (30) days after its disclosure and thereafter shall remain Confidential
Information if within such 30-day period after such disclosure the disclosing
Party delivers to the other Party a written document or documents describing the
Know-How or other information or material and referencing the place and date of
such oral, visual or written disclosure and the names of the persons to whom
such disclosure was made or (b) such information is of the type that is
customarily considered to be confidential information by persons engaged in
activities that are substantially similar to the activities being engaged in by
the Parties pursuant to this Agreement. "CONFIDENTIAL INFORMATION" shall not
include information: (i) which is or becomes generally available to the public
other than as a result of disclosure thereof by the Receiving Party; (ii) which
is lawfully received by the Receiving Party on a non-confidential basis from a
Third Party that is not itself under any obligation of confidentiality or
nondisclosure to the Disclosing Party or any other Person with respect to such
information; (iii) which is already known to the Receiving Party at the time of
disclosure by the Disclosing Party, or (iv) which can be shown by the Receiving
Party to have been independently developed by the Receiving Party without
reference to the Disclosing Party's Confidential Information.

        1.19.   "CONTRACT YEAR". Contract Year means the period beginning on the
Effective Date and ending on December 31, 2003 (the "FIRST CONTRACT YEAR"), or
each succeeding twelve (12) month calendar year period thereafter during the
term of the Agreement (referred to as the "SECOND CONTRACT YEAR", "THIRD
CONTRACT YEAR", etc.).

        1.20.   "CONTROL" or "CONTROLLED". Control or Controlled means with
respect to any item of Know-How or any intellectual property right, the
possession, whether by ownership or license (other than pursuant to this
Agreement), by a Party (and, in the case of Momenta, any of its Affiliates) of
the ability to grant to the other Party access and/or a license as provided
herein under such item or right without violating the terms of any agreement or
arrangement with any Third Party existing before or after the Effective Date.

        1.21.   "DEVELOP" or "DEVELOPMENT". Develop or Development means, with
respect to the Product: (a) Characterization of the Product; (b) all activities
associated with the filing of an ANDA for the Product as provided for in this
Agreement, including, without limitation, preclinical and clinical
drug-development activities, such as, but not limited to, toxicology,
preclinical and clinical studies; (c) formulation, process development and
commercial scale-up

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(to the commercial batch size agreed upon in the Annual Collaboration Plans
which shall be a batch size that is commercially reasonable given expected
production) activities (including test-method development); (d) development of
quality assurance/quality control procedures; (e) with respect to the drug
substance for the Product, commercial scale validation and commercial scale
stability studies; (f) with respect to the drug product form of the Product,
commercial scale process validation, commercial scale stability studies,
packaging, tooling, package design, packaging validation and labeling
preparation; (g) statistical analysis; (h) regulatory affairs (including legal
activities with respect thereto); and (i) Product approval and registration
activities. "DEVELOP" or "DEVELOPMENT" does not include Commercialization or
Legal Activities.

        1.22.   "DEVELOPMENT COSTS". Development Costs means (a) all costs paid
by Sandoz, BCWI or Momenta to Third Parties after the Effective Date in
connection with the Development of the Product with respect to the U.S.
Territory which are incurred in accordance with the Annual Collaboration Plan,
including, without limitation, contractors and licensors in connection with the
Development of the Product; (b) those costs incurred by Momenta prior to the
Effective Date which are listed on SCHEDULE 1.22 (the "PRE-EXISTING COSTS"); and
(c) the costs, calculated pursuant to the definition of Manufacturing Costs, to
manufacture any commercial batch(es) of the Product prior to the first batch
which is usable as commercial inventory, and (d) any payments for Additional
FTEs. Development Costs do not include: (i) [**] for the [**]; (ii) [**] Costs;
(iii) [**] the Product; (iv) [**] the Product other than as indicated in clause
(c) above; (v) [**] pursuant to the [**]; (vi) [**] Costs; (vii) [**] Expenses;
or (viii) [**] Costs.

        1.23.   "DISTRICT COURT LEGAL CLEARANCE". District Court Legal Clearance
means, with respect to the U.S. Territory, in the event that Orange Book
Litigation occurs prior to the granting of ANDA Final Approval for an ANDA filed
by Sandoz or any of its Affiliates for the Product, the earlier of (a) a
determination, including a summary judgment, from a federal district court (a
"DISTRICT COURT") in the Orange Book Litigation (a "DISTRICT COURT DECISION")
that marketing the Product by or on behalf of Sandoz does not infringe Aventis'
Patent Rights, or (b) a determination, from a federal district court, in a
patent infringement suit between Aventis and a Third Party, which would permit
the marketing of the Product by or on behalf of Sandoz without infringing
Aventis' Patent Rights (i) because such Patent Rights have been declared invalid
or unenforceable or (ii) if such Patent Rights have not been declared invalid or
unenforceable, in Sandoz's reasonable judgment.

        1.24.   "EXCESS COSTS". Excess Costs means the sum of (a) the amount by
which [**], (b) any [**] Costs, and (c) any [**] Costs (notwithstanding any [**]
with respect to [**]).

        1.25.   "EXECUTIVE OFFICERS". Executive Officers mean (a) the Chief
Executive Officer, Chief Financial Officer or Vice President of Business
Development of Sandoz (or an officer of Sandoz designated by any of the
foregoing officers) (the relevant officer, the "SANDOZ EXECUTIVE OFFICER"), (b)
the Head Caribic of BCWI (or an officer of BCWI designated by such person) (the
relevant officer, the "BCWI EXECUTIVE OFFICER"), and (c) the Chief Executive
Officer of Momenta (or an executive officer of Momenta designated by such
officer) (the relevant officer, the "MOMENTA EXECUTIVE OFFICER").

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        1.26.   "FDA". FDA means the United States Food and Drug Administration,
or any successor agency thereto.

        1.27.   "FIELD". Field means the injectable administration of the
Product for any and all medical indications.

        1.28.   "FINAL LEGAL CLEARANCE". Final Legal Clearance means, with
respect to the U.S. Territory, (a) the absence of Patent Litigation pursuant to
21 U.S.C. 355(c)(3)(C) or 355(j)(5)(B) with respect to the patents listed in the
Orange Book for Lovenox(R) ("ORANGE BOOK LITIGATION") prior to the granting of
ANDA Final Approval for an ANDA filed by Sandoz or any of its Affiliates for the
Product, or (b) in the event that Orange Book Litigation occurs prior to the
granting of ANDA Final Approval for an ANDA filed by Sandoz or any of its
Affiliates for the Product, the earliest of: (i) receipt by Sandoz or any of its
Affiliates of a final, unappealable judgment that determines that marketing of
the Product by or on behalf of Sandoz does not infringe Aventis' Patent Rights;
or (ii) receipt by a Third Party of a final, unappealable judgment in a patent
infringement suit between Aventis and such Third Party, which would permit the
marketing of the Product by or on behalf of Sandoz without infringing Aventis'
Patent Rights either (x) because such Patent Rights have been declared invalid
or unenforceable, or (y) if such Patent Rights have not been declared invalid or
unenforceable (in Sandoz's reasonable judgment); or (iii) a Settlement.

        1.29.   "FIRST COMMERCIAL SALE". First Commercial Sale means the first
commercial sale of the Product in the U.S. Territory as part of a nationwide
introduction by Sandoz, its Affiliates and/or distributors. Sales for test
marketing, clinical trial purposes or compassionate or similar use shall not
give rise to a First Commercial Sale.

        1.30.   "FRAGMIN OPPORTUNITY". Fragmin Opportunity means the research,
development, manufacturing or commercialization of dalteparin as a generic
version of Fragmin.

        1.31.   "FTE". FTE means a full time equivalent person year (consisting
of a total of [**] hours per year) of scientific, technical or managerial work
on or directly related to the Collaborative Program.

        1.32.   "FTE RATE". FTE Rate means U.S.$[**] per FTE.

        1.33.   "IMPROVED ENOXAPARIN". Improved Enoxaparin means any improved
form of enoxaparin which meets the specifications for [**] as of the Effective
Date and for which approval by the FDA would require the filing of a New Drug
Application under Section [**] of the FD&C Act ([**]).

        1.34.   "IMPROVEMENT". Improvement means any enhancement to Sandoz
Know-How, Momenta Know-How, Sandoz Collaboration Know-How or Momenta
Collaboration Know-How, as the case may be, based on and arising from exposure
to such Know-How and made during the conduct of the Collaborative Program,
including enhancements made to such Improvements made during the conduct of the
Collaborative Program.

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        1.35.   "JOINT COLLABORATION IP". Joint Collaboration IP means Joint
Collaboration Know-How and Joint Collaboration Patent Rights.

        1.36.   "JOINT COLLABORATION KNOW-HOW". Joint Collaboration Know-How
means all Know-How constituting, based upon or derived from inventions or
developments which are conceived and reduced to practice or developed jointly by
Sandoz or its Affiliates, on the one hand, and Momenta or its Affiliates, on the
other hand, during and in the conduct of the Collaborative Program, excluding
those Improvements to Sandoz Know-How, Improvements to Sandoz Collaboration
Know-How, Improvements to Momenta Know-How or Improvements to Momenta
Collaboration Know-How which are made jointly by Sandoz or its Affiliates, on
the one hand, and Momenta or its Affiliates, on the other hand.

        1.37.   "JOINT COLLABORATION PATENT RIGHTS". Joint Collaboration Patent
Rights means all Patent Rights throughout the world covering the Joint
Collaboration Know-How.

        1.38.   "JOINT PRODUCT-SPECIFIC KNOW-HOW". Joint Product-Specific
Know-How means all Joint Collaboration Know-How which solely relates to the
Product and does not relate, or cannot be used with, any other product or for
any other general purpose.

        1.39.   "JOINT PRODUCT-SPECIFIC PATENT RIGHTS". Joint Product-Specific
Patent Rights means all Patent Rights throughout the world covering Joint
Product-Specific Know-How.

        1.40.   "KNOW-HOW". Know-How means any information and material that is
confidential and proprietary, including, without limitation, ideas, concepts,
discoveries, inventions, developments, improvements, know-how, trade secrets,
designs, devices, equipment, process conditions, algorithms, notation systems,
works of authorship, computer programs, technologies, formulas, techniques,
methods, procedures, assay systems, applications, data, documentation, reports,
sugars, polysaccharides, heparinases, enzymes, reagents, glycoproteins,
proteins, peptides, glycoconjugates, primers, plasmids, vectors, expression
systems, cells, cell lines, antibodies, organisms, chemical compounds, products
and formulations, whether patentable or otherwise. Know-How shall also include
non-confidential information and material to the extent such information and
material first lost its confidentiality by virtue of its disclosure in an issued
patent or published patent application, a filing with a Regulatory Authority or
as part of a legal proceeding.

        1.41.   "LABEL". Label shall mean any package labeling designed for use
with the Product, pursuant to the terms of this Agreement, in accordance with
cGMP, including the package insert for such Product, that is approved by the FDA
pursuant to the terms of this Agreement; and any variation of such term, such as
"LABELED" or "LABELING", shall mean the act of doing the foregoing, and
"LABELER" shall mean a Party or Third Party who performs the act of Labeling.

        1.42.   "LEGAL ACTIVITIES". Legal Activities means (a) all
Product-Specific Patent Activities, and (b) all activities with respect to Legal
Clearance.

        1.43.   "LEGAL CLEARANCE". Legal Clearance means collectively District
Court Legal Clearance and Final Legal Clearance.

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        1.44.   "LEGAL CLEARANCE COSTS". Legal Clearance Costs means all legal
and related costs incurred to achieve Legal Clearance; provided, however, that
Legal Clearance Costs specifically exclude (a) Settlement Costs, and (b) the
cost of any attorneys which Momenta independently involves in the activities to
achieve Legal Clearance (which shall be the sole responsibility of Momenta),
unless the JSC agrees that such costs should be included in Legal Clearance
Costs.

        1.45.   "LEGAL EXPENSES". Legal Expenses means, with respect to the U.S.
Territory: (a) Product-Specific Patent Costs; (b) Legal Clearance Costs; (c) all
Liabilities related to Patent Litigation; (d) all Liabilities incurred by the
Parties or the Indemnified Parties with respect to any claims described in
Section 12.1(e); and (e) all Liabilities incurred by the Sandoz Parties with
respect to any claims or demands related to the Product that are commenced by
Aventis or any Third Party against any Sandoz Indemnified Party based on the
activities of Momenta or the Sandoz Parties (including those undertaken by
Affiliates or Third Parties on behalf of Momenta or the Sandoz Parties) [**]
pursuant to this Agreement. Notwithstanding any provision to the contrary
herein, Legal Expenses do not include: (i) damages (including [**]) due to
Aventis as a result of a Pre Final Legal Clearance Launch; (ii) Product
Liability Costs; and (iii) Settlement Costs.

        1.46.   "LOCKED MANUFACTURING PROCESS". Locked Manufacturing Process
means, with respect to the Product, an economically practical, highly controlled
and highly reproducible manufacturing process that enables the manufacture of
Characterized Product to FDA standards (including compatibility with cGMP) and
in accordance with any ANDA requirements for the Product, including without
limitation the Product's FDA specifications.

        1.47.   "LOVENOX(R)-EQUIVALENT PRODUCT". Lovenox(R)-Equivalent Product
means (a) Lovenox(R) in injectable form sold as a brand, including Lovenox(R)
sold by Aventis using another tradename, such as Clexane(R) (collectively,
"BRANDED LOVENOX"), or (b) any product sold in the U.S. Territory (other than
Branded Lovenox) that is a generic AB-rated or AP-rated equivalent to Lovenox(R)
in injectable form.

        1.48.   "MANUFACTURING COSTS". Manufacturing Costs means, with respect
to the Product, the aggregate of each Party's cost to commercially manufacture
(including the buildup of commercial inventory) and/or Label the Product,
calculated as follows: (a) if the Product is manufactured and/or Labeled by a
Party or its Affiliate, then Manufacturing Costs shall be determined as set
forth on SCHEDULE 1.48; or (b) if the Product is manufactured and/or Labeled by
a Third Party manufacturer, Manufacturing Costs shall equal the costs as
invoiced by such Third Party manufacturer for the manufacture and/or Labeling of
a specified quantity of the Product, plus any of the costs set forth on SCHEDULE
1.48 that are incurred by the Parties or their Affiliates in completing the
manufacture, Labeling and delivery to a warehouse(s) designated by the Sandoz
Parties of such quantity of the Product.

If there are any Third Party Royalties payable hereunder, such amounts shall be
considered a Manufacturing Cost for purposes of calculating any Profit Interest
payable to Momenta hereunder.

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        1.49.   "MARKETING APPROVAL". Marketing Approval means the approval of
the FDA necessary and sufficient for the marketing and First Commercial Sale of
the Product in the U.S. Territory.

        1.50.   "M118 OPPORTUNITY". M118 Opportunity means the research,
development, manufacturing or commercialization of Momenta's low molecular
weight heparin candidate known as M118.

        1.51.   "MIT". MIT means Massachusetts Institute of Technology.

        1.52.   "MIT AGREEMENT". MIT Agreement means the Amended and Restated
Exclusive Patent License Agreement by and between MIT and Momenta, dated as of
November 1, 2002 and as amended by a First Amendment dated November 15, 2002 and
letter agreements dated September 12, 2003 and October 22, 2003, as the same may
be amended from time to time.

        1.53.   "MOMENTA COLLABORATION KNOW-HOW". Momenta Collaboration Know-How
means (a) all Know-How constituting, based upon or derived from inventions or
developments which are conceived and reduced to practice or developed solely by
the employees, contractors (subject to Section 8.3), consultants or agents of
Momenta or its Affiliates during, and in the conduct of, the Collaborative
Program, excluding Improvements to Sandoz Know-How or Improvements to Sandoz
Collaboration Know-How, and (b) (i) Improvements to Momenta Know-How or (ii)
Improvements to Momenta Collaboration Know-How, which, with respect to each of
(b)(i) and (b)(ii), are made solely by the employees, contractors, consultants
or agents of Sandoz or its Affiliates, or jointly by the employees, contractors,
consultants or agents of Sandoz or its Affiliates, on the one hand, and by the
employees, contractors, consultants or agents of Momenta or its Affiliates, on
the other hand, during, and in the conduct of, the Collaborative Program.

        1.54.   "MOMENTA COLLABORATION PATENT RIGHTS". Momenta Collaboration
Patent Rights means all Patent Rights throughout the world covering Momenta
Collaboration Know-How that are Controlled by Momenta.

        1.55.   "MOMENTA INDEMNIFIED PARTIES". Momenta Indemnified Parties means
Momenta, Momenta's Affiliates, any of their successors or assigns, and any of
their respective then-current or then-former directors, officers, employees,
consultants, agents, suppliers, contract manufacturers, contract service
providers, Third Parties engaged to perform activities under the Collaborative
Program, and MIT (including MIT's trustees, officers, faculty, students,
employees, and agents).

        1.56.   "MOMENTA IP". Momenta IP means Momenta Know-How, Momenta
Collaboration Know-How, Momenta Patent Rights and Momenta Collaboration Patent
Rights, including, without limitation, those license rights granted to Momenta
under the MIT Agreement to the extent such would be included in Momenta
Know-How, Momenta Collaboration Know-How, Momenta Patent Rights and Momenta
Collaboration Patent Rights.

        1.57.   "MOMENTA KNOW-HOW". Momenta Know-How means all Know-How which
(a) is Controlled by Momenta (i) as of the Effective Date or (ii) during the
term of the Collaborative

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Program, but which is not developed or acquired by Momenta or any of its
Affiliates in the conduct of the Collaborative Program, and (b) could reasonably
be used in the conduct of the Collaborative Program.

        1.58.   "MOMENTA PATENT RIGHTS". Momenta Patent Rights means all Patent
Rights throughout the world covering Momenta Know-How that are Controlled by
Momenta, including, without limitation, the Patent Rights listed on SCHEDULE
1.58.

        1.59.   "MOMENTA PRODUCT-SPECIFIC KNOW-HOW". Momenta Product-Specific
Know-How means all Momenta Know-How or Momenta Collaboration Know-How which
solely relates to the Product and does not relate, or cannot be used with, any
other product or for any other general purpose.

        1.60.   "MOMENTA PRODUCT-SPECIFIC PATENT RIGHTS". Momenta
Product-Specific Patent Rights means all Patent Rights throughout the world
covering Momenta Product-Specific Know-How that are Controlled by Momenta.

        1.61.   "NET SALES". Net Sales means the gross amount invoiced by Sandoz
or its Affiliates (or, with respect to Section 11.6.3, Momenta, its Affiliates
and/or sublicensees) to Third Parties (whether an end-user, a distributor or
otherwise) for sales of the Product, less: (a) the total value (to the extent
actually allowed and taken directly with respect to such sales, as reflected in
the amount invoiced) of trade, cash and quantity discounts and/or rebates,
allowances, credits and charge backs, discounts in kind and/or other forms of
consideration offered as inducements for the purchase of such Product, and/or
required payments, including, without limitation, from (i) managed health care
organizations, (ii) federal, state or local governmental agency programs
(including Medicare and Medicaid or other similar programs in countries outside
the U.S. Territory), their agencies and purchasers and reimbursers, and (iii)
wholesalers and chain pharmacy buying groups and any other trade customers; and
(b) any credits or allowances booked on account of shelfstock and other price
adjustments, rejections or returns of Products previously sold; and (c) taxes,
customs charges, duties and any other governmental charges, levied on, absorbed,
or otherwise imposed on the production, importation, transportation, use or sale
of the Product (excluding national, state or local taxes based on income); and
(d) any Product recall costs, including Manufacturing Costs, costs of Product
destruction and out-of-pocket administrative costs, that are not identifiable as
being (x) the fault of the Sandoz Parties (in which case Sandoz shall be
responsible for such costs) or (y) the fault of Momenta (in which case Momenta
shall be responsible for such costs).

If there are any Third Party Royalties payable hereunder, such amounts shall be
subtracted in order to arrive at Net Sales for purposes of all royalty payments
to Momenta hereunder.

Such amounts shall be determined from the books and records of Sandoz or its
Affiliates (or, with respect to Section 11.6.3, Momenta, its Affiliates and/or
sublicensees), maintained in accordance with generally accepted accounting
principles, consistently applied.

In the case of any sale of the Product for consideration other than cash, such
as barter or countertrade, Net Sales shall be calculated on the fair market
value of consideration received.

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Each of the Sandoz Parties agrees not to use the Product as a loss leader. Each
of the Sandoz Parties also agrees that if either of them price the Product in
order to gain or maintain sales of other products, then for purposes of
calculating the payments due hereunder, the Net Sales shall be adjusted to
reverse any discount which was given to a customer that was in excess of
customary discounts for this Product (or, in the absence of relevant data for
this Product, other similar products under similar market conditions), if such
discount was given in order to gain or maintain sales of other products.

In the case of any sale of the Product between or among Sandoz or its Affiliates
(or, with respect to Section 11.6.3, Momenta, its Affiliates and sublicensees)
for resale, Net Sales shall be calculated as above only on the value charged or
invoiced on the first arm's length sale thereafter to a Third Party.

        1.62.   "NON-INJECTABLE OR IMPROVED ENOXAPARIN OPPORTUNITY".
Non-Injectable or Improved Enoxaparin Opportunity means the research,
development, manufacturing or commercialization of (a) enoxaparin to be
administered [**] or (b) Improved Enoxaparin.

        1.63.   "NON-OWNING PARTY". Non-Owning Party means, with respect to
Sandoz IP, Momenta, and, with respect to Momenta IP, BCWI (or Sandoz, if so
designated in writing by the Sandoz Parties).

        1.64.   "NON-U.S. TERRITORY". Non-U.S. Territory means all countries
outside the U.S. Territory.

        1.65.   "OWNING PARTY". Owning Party means, with respect to Momenta IP,
Momenta, and, with respect to Sandoz IP, BCWI (or Sandoz, if so designated in
writing by the Sandoz Parties).

        1.66.   "OWNING PARTY'S IP". Owning Party's IP means, with respect to
Momenta, the Momenta IP, and, with respect to a Sandoz Party, the Sandoz IP.

        1.67.   "PARTY". Party means Sandoz, BCWI or Momenta; "PARTIES" means
Sandoz, BCWI and Momenta.

        1.68.   "PATENT LITIGATION". Patent Litigation means (a) a claim or
demand by Aventis that alleges patent infringement against any Momenta
Indemnified Party or any Sandoz Indemnified Party based on (i) the activities of
the Sandoz Parties or Momenta (including those undertaken by Affiliates or Third
Parties on behalf of them) pursuant to this Agreement related to the Product
(including the manufacture of the Product), or (ii) the activities of the Sandoz
Parties or Momenta (including those undertaken by Affiliates or Third Parties on
behalf of them) [**] related to the Product (including the manufacture of the
Product), or (b) a declaratory judgment or other legal or equitable proceeding
approved by the JSC (or if the JSC cannot reach agreement, through the
provisions of Article 13) and commenced or joined by Momenta, Sandoz or one of
their Affiliates that seeks a judgment against Aventis that Sandoz, Momenta,
their Affiliates and/or Momenta's licensees have not infringed, or will not
infringe, any patent related to the Product (including the manufacture of the
Product), in each case, irrespective of the nature

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of the relief sought (which may include, without limitation, actual,
consequential or enhanced damages) and irrespective of the jurisdiction in which
such claim, demand or action is brought.

        1.69.   "PATENT RIGHT". Patent Right means a United States and/or
foreign patent or patent application and all substitutions, divisions,
continuations, continuations-in-part, reissues, reexaminations and extensions
thereof.

        1.70.   "PERSON". Person means any natural person, corporation, firm,
business trust, joint venture, association, organization, company, partnership
or other business entity, or any government, or any agency or political
subdivisions thereof.

        1.71.   "POST-LAUNCH QUARTER". Post-Launch Quarter means the Quarter in
which U.S. Launch Occurs (the "FIRST POST-LAUNCH QUARTER") or each subsequent
Quarter (referred to as the "SECOND POST-LAUNCH QUARTER", "THIRD POST-LAUNCH
QUARTER", etc.).

        1.72.   "POST-LAUNCH YEAR". Post-Launch Year means each four Post-Launch
Quarter period, with the First Post-Launch Year encompassing the period of the
First Post-Launch Quarter through the Fourth Post-Launch Quarter, the Second
Post-Launch Year encompassing the period of the Fifth Post-Launch Quarter
through the Eighth Post-Launch Quarter, etc.

        1.73.   "PRE FINAL LEGAL CLEARANCE LAUNCH". Pre Final Legal Clearance
Launch means the occurrence of the U.S. Launch prior to Final Legal Clearance.
For the avoidance of doubt, any such launch shall be in the sole discretion of
Sandoz.

        1.74.   "PRODUCT". Product means injectable enoxaparin and any improved
injectable form of enoxaparin for which Lovenox(R), as defined in the relevant
New Drug Application approved as of the Effective Date or any past or future
Supplemental New Drug Applications, is the reference listed drug and for which
an ANDA could be approved by the FDA, but specifically excluding any Improved
Enoxaparin. "PRODUCT" includes, without limitation, a Lovenox(R)-Equivalent
Product developed by the Parties pursuant to this Agreement.

        1.75.   "PRODUCT LIABILITY COSTS". Product Liability Costs means all
Liabilities incurred by any Momenta Indemnified Party or Sandoz Indemnified
Party arising from actual or alleged product liability with respect to the
Product, including, without limitation, any such Liabilities incurred or paid by
the Parties or the Indemnified Parties with respect to any claims described in
Sections 12.1(d) or 12.1(e) (as applicable).

        1.76.   "PRODUCT-SPECIFIC PATENT ACTIVITIES". Product-Specific Patent
Activities means all activities of the Parties with respect to the preparation,
filing, prosecution, maintenance, enforcement and invalidity defense of
Product-Specific Patent Rights to the extent such Product-Specific Patent Rights
are relevant to the exercise by the Sandoz Parties of the licenses granted in
Section 2.1.

        1.77.   "PRODUCT-SPECIFIC PATENT COSTS". Product-Specific Patent Costs
means all costs paid by a Party to Third Parties with respect to the
Product-Specific Patent Activities.

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        1.78.   "PRODUCT-SPECIFIC PATENT RIGHTS". Product-Specific Patent Rights
means Sandoz Product-Specific Patent Rights, Momenta Product-Specific Patent
Rights and Joint Product-Specific Patent Rights.

        1.79.   "PROFITS". Profits means Net Sales less (a) Selling Expenses and
(b) Manufacturing Costs for the Product sold (regardless of whether the Product
is rejected, returned or recalled).

        1.80.   "PROJECT LEADER". Project Leader means an executive appointed by
Momenta, on the one hand, or the Sandoz Parties, on the other hand, to serve as
such Party's principal coordinator and liaison for the Collaborative Program.
The Project Leader appointed by the Sandoz Parties is referred to as the "SANDOZ
PROJECT LEADER" and the Project Leader appointed by Momenta is referred to as
the "MOMENTA PROJECT LEADER."

        1.81.   "QUARTER". Quarter means each three month period ending March
31, June 30, September 30 and December 31 in each calendar year.

        1.82.   "REGULATORY AUTHORITY". Regulatory Authority means any federal,
national, multinational, state, provincial or local regulatory agency,
department, bureau or other governmental entity with authority over the testing,
manufacture, use, storage, import, promotion, marketing and sale of a
therapeutic product in a country, including the FDA.

        1.83.   "SANDOZ COLLABORATION KNOW-HOW". Sandoz Collaboration Know-How
means (a) all Know-How constituting, based upon or derived from inventions or
developments which are conceived and reduced to practice or developed solely by
the employees, contractors (subject to Section 8.3), consultants or agents of
Sandoz or its Affiliates during, and in the conduct of, the Collaborative
Program, excluding Improvements to Momenta Know-How or Improvements to Momenta
Collaboration Know-How, and (b) (i) Improvements to Sandoz Know-How or (ii)
Improvements to Sandoz Collaboration Know-How, which, with respect to each of
(b)(i) and (b)(ii), are made solely by the employees, contractors, consultants
or agents of Momenta or its Affiliates, or jointly by the employees,
contractors, consultants or agents of Sandoz or its Affiliates, on the one hand,
and by the employees, contractors, consultants or agents of Momenta or its
Affiliates, on the other hand, during, and in the conduct of, the Collaborative
Program.

        1.84.   "SANDOZ COLLABORATION PATENT RIGHTS". Sandoz Collaboration
Patent Rights means all Patent Rights throughout the world covering Sandoz
Collaboration Know-How that are Controlled by a Sandoz Party.

        1.85.   "SANDOZ INDEMNIFIED PARTIES". Sandoz Indemnified Parties means
Sandoz, BCWI, their Affiliates, any of their successors or assigns, and any of
their respective then-current or then-former directors, officers, employees,
consultants, suppliers, contract manufacturers, contract service providers, and
Third Parties engaged to perform activities under the Collaborative Program.

        1.86.   "SANDOZ IP". Sandoz IP means Sandoz Know-How, Sandoz
Collaboration Know-How, Sandoz Patent Rights and Sandoz Collaboration Patent
Rights. Sandoz IP expressly excludes the intellectual property rights of any
Affiliate of the Sandoz Parties, unless such

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intellectual property rights are Controlled by a Sandoz Party, it being
understood that the Sandoz Parties shall have the obligation to obtain Control
set forth in Section 8.3.

        1.87.   "SANDOZ KNOW-HOW". Sandoz Know-How means all Know-How which (a)
is Controlled by a Sandoz Party (i) as of the Effective Date or (ii) during the
term of the Collaborative Program, but which is not developed by Sandoz or its
Affiliates or acquired by Sandoz or its Affiliates in the conduct of the
Collaborative Program, and (b) is contributed and approved for use by a Sandoz
Party in the conduct of the Collaborative Program, it being understood that any
such contribution shall be in the sole discretion of such Sandoz Party and that,
unless the Parties otherwise agree in writing, such Sandoz Party shall not
charge Momenta for any such contribution.

        1.88.   "SANDOZ PATENT RIGHTS". Sandoz Patent Rights means all Patent
Rights throughout the world covering Sandoz Know-How that are Controlled by a
Sandoz Party.

        1.89.   "SANDOZ PRODUCT-SPECIFIC KNOW-HOW". Sandoz Product-Specific
Know-How means all Sandoz Know-How or Sandoz Collaboration Know-How which solely
relates to the Product and does not relate, or cannot be used with, any other
product or for any other general purpose.

        1.90.   "SANDOZ PRODUCT-SPECIFIC PATENT RIGHTS". Sandoz Product-Specific
Patent Rights means all Patent Rights throughout the world covering Sandoz
Product-Specific Know-How that are Controlled by a Sandoz Party.

        1.91.   "SELLING EXPENSES". Selling Expenses means Sandoz's or its
Affiliates' expenditures to market, distribute and sell the Product, which shall
be deemed for purposes of this Agreement to be equal to [**] percent ([**]%) of
Net Sales of such Product for each applicable period.

        1.92.   "SETTLEMENT". Settlement means an agreement or settlement, made
at any time, between a Sandoz Party or its Affiliate(s), on the one hand, and
Aventis, on the other hand, that finally resolves any existing Patent Litigation
and precludes any future Patent Litigation by Aventis against the Sandoz
Parties, their Affiliates and the Momenta Indemnified Parties related to the
Product, such that the Product may be marketed by or continue to be marketed by
or on behalf of Sandoz or its Affiliates subject to ANDA Final Approval of an
ANDA filed by Sandoz or any of its Affiliates for the Product.

        1.93.   "SETTLEMENT COSTS". Settlement Costs means all amounts paid to
Aventis (whether [**] or similar arrangement, including without limitation [**]
in accordance with Section 6.2.2) in order to achieve a Settlement.

        1.94.   "STABILITY STUDIES". Stability Studies means, with respect to
the Product, the performance of stability testing at one-tenth commercial scale
in accordance with the stability protocol set forth in the ANDA for the Product.

        1.95.   "SUPPLY CHAIN". Supply Chain, with respect to Product, means
stable, reliable, and commercially practical sources to obtain all starting
materials, biological products,

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biological molecules, chemicals, precursors, intermediates, and reagents of
sufficient quantity, quality, and purity necessary to manufacture the required
commercial quantities of the Product according to the Locked Manufacturing
Process. "SUPPLY CHAIN" includes commercial sources of all packaging components
and packaging materials, including primary and printed packaging materials
according to the standards set forth in the ANDA for the Product.

        1.96.   "THIRD PARTY". Third Party means any Person other than a Party
or any of its Affiliates.

        1.97.   "THIRD-PARTY COMPETITOR". Third-Party Competitor means each
Third Party (including, [**], collectively with all of such Third Party's
Affiliates, licensees and/or distributors, which Third Party owns, itself or
through its Affiliates, [**] in the U.S. Territory for [**] Products and which
Third Party is marketing, itself or through its Affiliates, licensees and/or
distributors, [**] in the U.S. Territory; PROVIDED, HOWEVER, THAT Third-Party
Competitor shall exclude Sandoz's and BCWI's Affiliates and distributors. If
[**], it shall be termed the "[**]".

        1.98.   "THIRD PARTY ROYALTIES". Third Party Royalties means any
royalties, license fees or other monetary payments made by the Sandoz Parties
(either directly or via reimbursement to Momenta) to any Third Party in
consideration of a license(s) under such Third Party patent(s), know-how or
other intellectual property rights, when such license is reasonably determined
by the JPT to be necessary to commercially manufacture and/or sell the Product
without infringing such Third Party intellectual property rights; PROVIDED,
HOWEVER, that Third Party Royalties shall not include any payments to Third
Party contractors hired by Momenta or any Sandoz Parties, with prior approval of
the JPT, in order to provide services in connection with Development activities
under this Agreement, under which royalty-free licenses are granted to
intellectual property created during the course of providing such services.

        1.99.   "U.S. LAUNCH". U.S. Launch means the time when Sandoz, its
Affiliates or distributors achieve the First Commercial Sale of the Product in
the U.S. Territory.

        1.100.  "U.S. TERRITORY". U.S. Territory shall mean the fifty states of
the United States of America, the District of Columbia and all territories and
possessions of the United States of America and any other location where the FDA
has jurisdiction over medicinal products intended for human use.

        1.101.  OTHER DEFINED TERMS. Each of the following definitions is set
forth in the section of this Agreement indicated below:

<Table>
<Caption>
                        Definition                                    Section
                        ----------                                    -------
        <S>                                                        <C>
        Actual Momenta Economic Interest                           Schedule 4.3
        Additional Excessive Cost Termination                      11.5.2
        Additional Excessive Cost Termination Option Period        11.5.2
        Additional Excessive Cost Trigger                          11.5.2
        Additional FTE's                                           4.2
        Agreement                                                  Preamble
        Aventis Persons                                            1.6
</Table>

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<Table>
        <S>                                                        <C>
        Aventis [**]                                               1.97
        Aventis [**]                                               4.8.1
        BCWI                                                       Preamble
        BCWI Executive Officer                                     1.25
        Branded Lovenox                                            1.47
        Carryforward                                               Schedule 4.3
        Commercial Milestone Payments                              4.10.2
        Commercial Viability Termination                           11.3
        Commercial Viability Trigger                               11.3
        Controlled Contractors                                     3.1
        Cost Cap                                                   4.1
        Disclosing Party                                           10.2
        District Court                                             1.23
        District Court Decision                                    1.23
        Economic Interest Variance                                 Schedule 4.3
        Entire Capacity                                            Schedule 1.48
        Effective Date                                             Preamble
        FD&C Act                                                   1.3
        Final Misappropriation Determination                       12.2
        Force Majeure Event                                        14.15
        Fragmin Notice                                             3.1
        Fragmin Response                                           3.1
        Fragmin Response Period                                    3.1
        FTE Records                                                4.2
        Full Capacity                                              Schedule 1.48
        Full Milestone Payment(s)                                  4.10.2
        Indemnified Party                                          12.3
        Indemnifying Party                                         12.3
        Initial Excessive Cost Termination                         11.5.1
        Initial Excessive Cost Termination Option Period           11.5.1
        Initial Excessive Cost Trigger                             11.5.1
        Initial Non-U.S. Territory Negotiation Period              3.4.2
        Invalidity Claim                                           8.6
        Joint Project Team / JPT                                   5.2
        Labeler                                                    1.41
        Joint Steering Committee / JSC                             5.3
        Legal Strategy Diminishment                                11.4
        Liabilities                                                12.1
        Milestone Payment Quarter                                  4.10.2
        M118 Notice                                                3.2
        M118 Response                                              3.2
        M118 Response Period                                       3.2
        MIT Associates                                             14.16
        Momenta                                                    Preamble
</Table>

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<Table>
        <S>                                                        <C>
        Momenta Assigned Improvements                              8.1.1
        Momenta Economic Interest                                  Schedule 4.3
        Momenta Executive Officer                                  1.25
        Momenta Project Leader                                     1.80
        Momenta Share of Excess Costs                              Schedule 4.3
        New Excess Costs                                           Schedule 4.3
        [**] Period                                                4.7.1
        [**] Royalty                                               4.7.1
        Non-Injectable or Improved Enoxaparin Response             3.3.1
        Non-Injectable or Improved Enoxaparin Notice               3.3.1
        Non-Injectable or Improved Enoxaparin Response Period      3.3.1
        Non-U.S. Option                                            3.4.1
        Non-U.S. Option Period                                     3.4.1
        Non-U.S. Territory Agreement                               3.4.2
        [**] Period                                                4.5
        Orange Book Litigation                                     1.28
        Pleadings                                                  12.3.3
        Post-[**] Period                                           4.6.1
        Post-[**] Royalty                                          4.6.1
        Pre-Existing Costs                                         1.21
        Prior Confidentiality Agreement                            10.1
        Product Records                                            4.11.4
        Profit Interest                                            4.5
        Program Output                                             3.4.6
        Receiving Party                                            10.2
        Regulatory Milestone Payment                               4.10.1
        Representing Party                                         9.1
        Sandoz                                                     Preamble
        Sandoz Assigned Improvements                               8.1.1
        Sandoz Executive Officer                                   1.25
        Sandoz Party                                               Preamble
        Sandoz Parties                                             Preamble
        Sandoz Milestone Termination                               11.4
        Sandoz Milestone Trigger                                   11.4
        Sandoz Parties Royalty                                     11.6.3
        Sandoz Project Leader                                      1.80
        Supply Continuation Plan                                   11.2.2
        Supply Interruption                                        11.2.2
        Supply Interruption Notice                                 11.2.2
        Term                                                       11.1
        Third Party Term Sheet                                     3.4.5
        Third Party Term Sheet Notice                              3.4.5
        True-Up Amount                                             Schedule 4.3
</Table>

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2.      GRANT OF RIGHTS

        2.1.    MOMENTA LICENSE GRANTS. Subject to the terms and conditions of
this Agreement, Momenta hereby grants to BCWI during the Term, (a) an exclusive
license, without the right to grant sublicenses, under Momenta IP and under
Momenta's rights in the Joint Collaboration IP, to Develop, make, have made,
use, sell, offer to sell, lease, import and export the Product in the U.S.
Territory in the Field, and (b) a non-exclusive license, with no right to grant
sublicenses, under the Momenta IP to make, have made, and use the Product in the
Non-U.S. Territory, but only for the purposes of sale of the Product in or into
the U.S. Territory; PROVIDED, HOWEVER, THAT Momenta retains the right to
practice, and to grant sublicenses, under Momenta IP and under Momenta's rights
in the Joint Collaboration IP in the U.S. Territory in the Field to (i) perform
its obligations to the Sandoz Parties under this Agreement, including, without
limitation, to conduct the Momenta activities under this Agreement and in the
Annual Collaboration Plans and (ii) make and have made the Product in the U.S.
Territory solely for the purposes of sales of the Product in the Field (A) in
those countries in the Non-U.S. Territory for which Sandoz does not, during the
Non-U.S. Option Period, exercise the Non-U.S. Option, or (B) if Sandoz exercises
the Non-U.S. Option within the Non-U.S. Option Period, in those countries in the
Non-U.S. Territory for which Sandoz and Momenta do not execute a Non-U.S.
Territory Agreement either during the Initial Non-U.S. Territory Negotiation
Period or pursuant to Section 3.4.5. Notwithstanding the foregoing prohibition
on sublicensing, (a) BCWI may sublicense its rights under this Section 2.1 to
Sandoz to the extent it deems necessary for Sandoz to perform its obligations
under this Agreement, and (b) subject to the provisions of Section 8.3.3, BCWI
may sublicense its rights under this Section 2.1 to an Affiliate of BCWI other
than Sandoz to the extent as may be permitted under the Annual Collaboration
Plans or as otherwise approved in writing by Momenta.

        2.2.    SANDOZ PARTIES LICENSE GRANTS. Subject to the terms and
conditions of this Agreement, the Sandoz Parties hereby grant to Momenta, during
the term of this Agreement, a worldwide, non-exclusive, royalty-free license,
without the right to grant sublicenses (except to the extent as may be permitted
under the relevant Annual Collaboration Plan or as otherwise approved in writing
by the relevant Sandoz Party) under Sandoz IP and under the Sandoz Parties'
rights in the Joint Collaboration IP, solely to the extent necessary or
appropriate to perform Momenta's obligations to the Sandoz Parties under this
Agreement, including, without limitation, to conduct the Momenta activities
under this Agreement and in the Annual Collaboration Plans.

        2.3.    EXCLUSIVITY. Subject to Momenta's retained right in Section 2.1,
except as otherwise agreed in writing by the Parties, Momenta agrees that it
shall not, and shall ensure that its Affiliates do not, during the Term, grant
any license in Momenta IP or Joint Collaboration IP to any Third Party to
Develop, make, have made, use, sell, offer to sell, lease, import, export or
otherwise Commercialize the Product in the Field in the U.S. Territory. Except
as otherwise agreed in writing by the Parties, each Sandoz Party agrees that it
shall not, and shall use reasonable efforts to cause its Affiliates not to,
during the Term, grant any license to any Third Party to Develop, make, have
made, use, sell, offer to sell, lease, import, export or otherwise Commercialize
the Product in the Field in the U.S. Territory, except to the extent necessary
or appropriate to perform the Sandoz Parties' obligations to Momenta under this
Agreement;

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PROVIDED, HOWEVER, THAT if an Affiliate of any Sandoz Party grants any such
license to any Third Party, it shall be considered a breach of this Agreement by
the Sandoz Parties. Momenta shall, and shall ensure that its Affiliates,
exclusively develop and Commercialize the Product with the Sandoz Parties during
the Term in the U.S. Territory. Each Sandoz Party shall, and shall use
reasonable efforts to ensure that its Affiliates, exclusively develop and
Commercialize the Product with Momenta during the Term in the U.S. Territory;
PROVIDED, HOWEVER, THAT if an Affiliate of any Sandoz Party develops or
commercializes the Product without Momenta during the Term in the U.S.
Territory, it shall be considered a breach of this Agreement by the Sandoz
Parties.

        2.4.    RETAINED RIGHTS. Any rights of Momenta not expressly granted to
Sandoz or BCWI under the provisions of this Agreement shall be retained by
Momenta and any rights of Sandoz or BCWI not expressly granted to Momenta under
the provisions of this Agreement shall be retained by Sandoz or BCWI,
respectively.

        2.5.    THIRD PARTY LICENSOR RIGHTS. The rights granted in Sections 2.1
and 2.2 are granted to the extent permitted or qualified by the nature of the
licenses granted by the relevant Third Party licensors, if any, of Momenta IP or
Sandoz IP, as the case may be. The Party receiving such license shall comply
with all restrictions and obligations imposed by such Third Party licensors;
PROVIDED, HOWEVER, THAT, if Momenta or a Sandoz Party, as the case may be,
enters into a license with a Third Party licensor for any intellectual property
that may be considered Momenta IP or Sandoz IP, respectively, Momenta or such
Sandoz Party shall notify the Sandoz Parties or Momenta, respectively, of the
restrictions and obligations imposed by such Third Party licensor, and, if the
Sandoz Parties or Momenta, respectively, do not wish to comply with such
restrictions and obligations, such licensed intellectual property shall not be
considered Momenta IP or Sandoz IP, respectively, hereunder. Sandoz acknowledges
receipt of a copy of the MIT Agreement from Momenta. Momenta represents that the
copy of the MIT Agreement delivered to Sandoz in accordance with the foregoing
represents the MIT Agreement as in effect as of the Effective Date.

3.      ADDITIONAL RIGHTS

        3.1.    FRAGMIN OPPORTUNITY; RIGHT OF FIRST NEGOTIATION. During the
Term, prior to entering into any detailed negotiations regarding key terms
and/or entering into any contract, agreement, term sheet, understanding or
arrangement (verbal or written) with a Commercial Third Party (other than Third
Party contractors such as contract research organizations, contract
manufacturers, contract employees, consultants and the like which merely conduct
activities on behalf of Momenta and subject to Momenta's supervision and control
("CONTROLLED CONTRACTORS")) with respect to a Fragmin Opportunity in the U.S.
Territory or the Non-U.S. Territory, Momenta shall provide written notice to the
Sandoz Parties of its bona fide present intent to engage in such activities at
such time (the "FRAGMIN NOTICE"), which Fragmin Notice shall include information
in reasonable detail sufficient to enable the Sandoz Parties to make an informed
decision with respect to such Fragmin Opportunity; PROVIDED, HOWEVER, THAT this
Section 3.1 shall not prevent Momenta from participating in general discussions
or negotiations with Third Parties with respect to a Fragmin Opportunity in the
U.S. Territory or the Non-U.S. Territory. If either (but not both) of the Sandoz
Parties notifies Momenta in writing within thirty

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(30) days of receipt of the Fragmin Notice (the "FRAGMIN RESPONSE PERIOD", such
notice, the "FRAGMIN RESPONSE") that it has a bona fide interest in discussing a
collaboration with Momenta with respect to such Fragmin Opportunity, Momenta and
such Sandoz Party shall enter into good faith negotiations on an exclusive
basis, on such terms as may be mutually agreeable. If (a) neither Sandoz Party
indicates during the Fragmin Response Period that it is interested in discussing
such Fragmin Opportunity, (b) the Sandoz Parties indicate in writing during the
Fragmin Response Period that they have no interest in such Fragmin Opportunity,
or (c) one of the Sandoz Parties indicates such an interest during the Fragmin
Response Period but Momenta and such Sandoz Party are unable, after good faith
negotiations, to reach mutual agreement and execute a definitive agreement with
respect to a collaboration with respect to such Fragmin Opportunity within [**]
from the date of the Fragmin Response (or such extended period as may be
approved in writing by Momenta and such Sandoz Party), Momenta shall be free for
a period of [**] thereafter to undertake detailed negotiations regarding key
terms and enter into a transaction (including execution of a definitive
agreement) relating to such Fragmin Opportunity with a Commercial Third
Party(ies), which, with respect only to clause (c) above, shall be on terms not
less favorable, taken as a whole, to Momenta than those last offered to the
applicable Sandoz Party. Momenta and the Sandoz Parties recognize that, in
evaluating the favorability to Momenta of the terms of such Third Party
transaction relating to such Fragmin Opportunity, numerous factors may be taken
into account and given appropriate weight, including, without limitation, the
amount of up-front payments, the amount and timing of subsequent license or
research payments, the royalty rate(s) or profit sharing terms, the definition
of territory, marketing and promotion rights, the purchase and pricing of
equity, if applicable, and the identity, experience and market position of such
Third Party(ies) in the relevant markets. If, after the expiration of such [**]
period, Momenta has not entered into a transaction with any Third Party with
respect to such Fragmin Opportunity, then Momenta and the Sandoz Parties shall
again follow the procedures described in this Section 3.1 with respect to such
Fragmin Opportunity. Momenta shall not be obligated to reveal to the Sandoz
Parties the identity of any Third Party involved in any such transaction.

        3.2.    M118 OPPORTUNITY; RIGHT OF FIRST NEGOTIATION. During the Term,
prior to entering into any detailed negotiations regarding key terms and/or
entering into any contract, agreement, term sheet, understanding or arrangement
(verbal or written) with a Commercial Third Party (other than Controlled
Contractors) with respect to an M118 Opportunity in the U.S. Territory or the
Non-U.S. Territory, Momenta shall provide written notice to the Sandoz Parties
of its bona fide present intent to engage in such activities at such time (the
"M118 NOTICE"), which M118 Notice shall include information in reasonable detail
sufficient to enable the Sandoz Parties to make an informed decision with
respect to such M118 Opportunity; PROVIDED, HOWEVER, THAT this Section 3.2 shall
not prevent Momenta from participating in general discussions or negotiations
with Third Parties with respect to an M118 Opportunity in the U.S. Territory or
the Non-U.S. Territory. If either (but not both) of the Sandoz Parties notifies
Momenta in writing within thirty (30) days of receipt of the M118 Notice (the
"M118 RESPONSE PERIOD", such notice, the "M118 RESPONSE") that it has a bona
fide interest in discussing a collaboration with Momenta with respect to such
M118 Opportunity, Momenta and such Sandoz Party shall enter into good faith
negotiations on an exclusive basis, on such terms as may be mutually agreeable.
If (a) neither Sandoz Party indicates during the M118 Response Period that it is
interested in discussing such M118 Opportunity, (b) the Sandoz Parties indicate
in writing during the M118 Response Period

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that they have no interest in such M118 Opportunity, or (c) one of the Sandoz
Parties indicates such an interest during the M118 Response Period but Momenta
and such Sandoz Party are unable, after good faith negotiations, to reach mutual
agreement and execute a definitive agreement with respect to a collaboration
with respect to such M118 Opportunity within [**] from the date of the M118
Response (or such extended period as may be approved in writing by Momenta and
such Sandoz Party), Momenta shall be free for a period of [**] thereafter to
undertake detailed negotiations regarding key terms and enter into a transaction
(including execution of a definitive agreement) relating to such M118
Opportunity with a Commercial Third Party(ies), which, with respect only to
clause (c) above, shall be on terms not less favorable, taken as a whole, to
Momenta than those last offered to the applicable Sandoz Party. Momenta and the
Sandoz Parties recognize that, in evaluating the favorability to Momenta of the
terms of such Third Party transaction relating to such M118 Opportunity,
numerous factors may be taken into account and given appropriate weight,
including, without limitation, the amount of up-front payments, the amount and
timing of subsequent license or research payments, the royalty rate(s) or profit
sharing terms, the definition of territory, marketing and promotion rights, the
purchase and pricing of equity, if applicable, and the identity, experience and
market position of such Third Party(ies) in the relevant markets. If, after the
expiration of such [**] period, Momenta has not entered into a transaction with
any Third Party with respect to such M118 Opportunity, then Momenta and the
Sandoz Parties shall again follow the procedures described in this Section 3.2
with respect to such M118 Opportunity. Momenta shall not be obligated to reveal
to the Sandoz Parties the identity of any Third Party involved in any such
transaction.

        3.3.    NON-INJECTABLE OR IMPROVED ENOXAPARIN OPPORTUNITIES.

                3.3.1   U.S. TERRITORY. If, during the Term, Momenta intends to
                begin detailed negotiations regarding key terms and/or enter
                into any contract, agreement, term sheet, understanding or
                arrangement (verbal or written) with a Commercial Third Party
                (other than Controlled Contractors) with respect to a
                Non-Injectable or Improved Enoxaparin Opportunity in the U.S.
                Territory, Momenta shall provide written notice of such bona
                fide present intent to the Sandoz Parties (the "NON-INJECTABLE
                OR IMPROVED ENOXAPARIN NOTICE"), which Non-Injectable or
                Improved Enoxaparin Notice shall include information in
                reasonable detail sufficient to enable the Sandoz Parties to
                make an informed decision with respect to such Non-Injectable or
                Improved Enoxaparin Opportunity; PROVIDED, HOWEVER, THAT this
                Section 3.3 shall not prevent Momenta from participating in
                general discussions or negotiations with Third Parties with
                respect to a Non-Injectable or Improved Enoxaparin Opportunity
                in the U.S. Territory. If either (but not both) of the Sandoz
                Parties notifies Momenta in writing within [**] of receipt of
                the Non-Injectable or Improved Enoxaparin Notice (the
                "NON-INJECTABLE OR IMPROVED ENOXAPARIN RESPONSE PERIOD", such
                notice, the "NON-INJECTABLE OR IMPROVED ENOXAPARIN RESPONSE")
                that it has a bona fide interest in discussing a collaboration
                with Momenta with respect to such Non-Injectable or Improved
                Enoxaparin Opportunity, Momenta and such Sandoz Party shall
                enter into good faith negotiations on an exclusive basis, on
                such terms as may be mutually agreeable. If (a) neither Sandoz
                Party indicates during the Non-Injectable or Improved Enoxaparin
                Response Period that it is interested in discussing such

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                Non-Injectable or Improved Enoxaparin Opportunity, (b) the
                Sandoz Parties indicate in writing during the Non-Injectable or
                Improved Enoxaparin Response Period that they have no interest
                in such Non-Injectable or Improved Enoxaparin Opportunity, or
                (c) one of the Sandoz Parties indicates such an interest during
                the Non-Injectable or Improved Enoxaparin Response Period but
                Momenta and such Sandoz Party are unable to, after good faith
                negotiations, reach mutual agreement and execute a definitive
                agreement with respect to a collaboration with respect to such
                Non-Injectable or Improved Enoxaparin Opportunity within [**]
                from the date of the Non-Injectable or Improved Enoxaparin
                Response (or such extended period as may be approved in writing
                by Momenta and such Sandoz Party), Momenta shall be free for a
                period of [**] thereafter, to undertake detailed negotiations
                regarding key terms and/or enter into a transaction (including
                execution of a definitive agreement) relating to such
                Non-Injectable or Improved Enoxaparin Opportunity with a
                Commercial Third Party(ies), which, with respect only to clause
                (c) above, shall be on terms not less favorable, taken as a
                whole, to Momenta than those last offered to the applicable
                Sandoz Party. Momenta and the Sandoz Parties recognize that, in
                evaluating the favorability to Momenta of the terms of such
                Third Party transaction relating to such Non-Injectable or
                Improved Enoxaparin Opportunity, numerous factors may be taken
                into account and given appropriate weight, including, without
                limitation, the amount of up-front payments, the amount and
                timing of subsequent license or research payments, the royalty
                rate(s) or profit sharing terms, the definition of territory,
                marketing and promotion rights, the purchase and pricing of
                equity, if applicable, and the identity, experience and market
                position of such Third Party(ies) in the relevant markets. If,
                after the expiration of such [**] period, Momenta has not
                entered into a transaction with any Third Party with respect to
                such Non-Injectable or Improved Enoxaparin Opportunity, then
                Momenta and the Sandoz Parties shall again follow the procedures
                described in this Section 3.3.1 with respect to such
                Non-Injectable or Improved Enoxaparin Opportunity. Momenta shall
                not be obligated to reveal to the Sandoz Parties the identity of
                any Third Party involved in any such transaction.

                3.3.2   NON-U.S. TERRITORY.

                a.      During the Non-U.S. Option Period, Momenta shall provide
                        a Non-Injectable or Improved Enoxaparin Notice under
                        Section 3.3.1 to the Sandoz Parties if Momenta has a
                        bona fide present intent to begin detailed negotiations
                        regarding key terms or enter into any contract,
                        agreement, term sheet, understanding or arrangement
                        (verbal or written) with a Commercial Third Party at
                        such time with respect to a Non-Injectable or Improved
                        Enoxaparin Opportunity in the Non-U.S. Territory, and
                        the provisions of Section 3.3.1 shall apply MUTATIS
                        MUTANDIS with respect to the Non-U.S. Territory.

                b.      During the Initial Non-U.S. Territory Negotiation
                        Period, if any, and during the term of the Non-U.S.
                        Territory Agreement, Momenta shall

                                      -22-
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                        provide a Non-Injectable or Improved Enoxaparin Notice
                        under Section 3.3.1 to the Sandoz Parties if Momenta has
                        a bona fide present intent to begin detailed
                        negotiations regarding key terms or enter into any
                        contract, agreement, term sheet, understanding or
                        arrangement (verbal or written) with a Commercial Third
                        Party at such time with respect to a Non-Injectable or
                        Improved Enoxaparin Opportunity in the portion of the
                        Non-U.S. Territory for which a Sandoz Party has
                        exercised the Non-U.S. Option or executed the Non-U.S.
                        Territory Agreement, as applicable, and the provisions
                        of Section 3.3.1 shall apply with respect to such
                        countries.

                c.      Notwithstanding the provisions of Sections 3.3.2(a) and
                        3.3.2(b), (i) if neither Sandoz Party indicates during
                        the Non-U.S. Option Period that it is interested in
                        exercising the Non-U.S. Option or the Sandoz Parties
                        indicate in writing during the Non-U.S. Option Period
                        that they have no interest in exercising the Non-U.S.
                        Option, Momenta shall have no further obligations to the
                        Sandoz Parties or their Affiliates with respect to the
                        Non-Injectable or Improved Enoxaparin Opportunity in the
                        Non-U.S. Territory; (ii) Momenta shall not be obligated
                        to enter into definitive agreements with a Sandoz Party
                        with respect to a Non-Injectable or Improved Enoxaparin
                        Opportunity in the Non-U.S. Territory unless and until
                        Momenta and a Sandoz Party have entered into the
                        Non-U.S. Territory Agreement; PROVIDED, HOWEVER, that
                        the negotiation period for any such Non-Injectable or
                        Improved Enoxaparin Opportunity in the Non-U.S.
                        Territory shall be tolled without penalty during the
                        Non-U.S. Option Period and the Initial Non-U.S.
                        Territory Negotiation Period; (iii) if a Sandoz Party
                        exercises the Non-U.S. Option but Momenta and such
                        Sandoz Party do not enter into the Non-U.S. Territory
                        Agreement either prior to the expiration of the Initial
                        Non-U.S. Territory Negotiation Period or pursuant to
                        Section 3.4.5, Momenta shall have no further obligations
                        to the Sandoz Parties or their Affiliates with respect
                        to the Non-Injectable or Improved Enoxaparin Opportunity
                        in the Non-U.S. Territory; (iv) if a Sandoz Party
                        exercises the Non-U.S. Option with respect to only a
                        portion of the Non-U.S. Territory, Momenta shall have no
                        further obligations to the Sandoz Parties or their
                        Affiliates with respect to a Non-Injectable or Improved
                        Enoxaparin Opportunity with respect to those countries
                        in the Non-U.S. Territory for which a Sandoz Party did
                        not exercise the Non-U.S. Option; and (v) this Section
                        3.3 shall not prevent Momenta from participating in
                        general discussions or negotiations with Third Parties
                        with respect to a Non-Injectable or Improved Enoxaparin
                        Opportunity in the Non-U.S. Territory.

        3.4.    NON-U.S. TERRITORY OPTION.

                3.4.1   OPTION. Momenta hereby grants to either (but not both)
                of the Sandoz Parties the exclusive option to commence
                negotiations to obtain an exclusive license to Develop and
                Commercialize the Product in all or part of the Non-U.S.
                Territory on terms to be determined in accordance with the
                provisions of this

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                Section 3.4 (the "NON-U.S. OPTION"). A Sandoz Party shall notify
                Momenta in writing as to its exercise of the Non-U.S. Option
                within four (4) months after the Effective Date (the "NON-U.S.
                OPTION PERIOD"). During the Non-U.S. Option Period, no Party
                shall, and each Party shall ensure that its Affiliates do not,
                develop or commercialize the Product with a Third Party in the
                Non-U.S. Territory. During the Initial Non-U.S. Negotiation
                Period, if any, no Party shall, and each Party shall ensure that
                its Affiliates do not, develop or commercialize the Product with
                a Third Party in the portion of the Non-U.S. Territory for which
                a Sandoz Party has exercised the Non-U.S. Option.

                3.4.2   INITIAL NON-U.S. TERRITORY NEGOTIATION PERIOD. Upon
                exercise by a Sandoz Party of the Non-U.S. Option, Momenta and
                such Sandoz Party shall negotiate in good faith a definitive
                agreement containing terms and conditions for the exclusive
                license in the portion of the Non-U.S. Territory for which such
                Sandoz Party has exercised the Non-U.S. Option in Section 3.4.1
                (the "NON-U.S. TERRITORY AGREEMENT"). Unless extended by mutual
                agreement of Momenta and such Sandoz Party, the negotiations
                shall cease after the first anniversary of the Effective Date
                (the "INITIAL NON-U.S. TERRITORY NEGOTIATION PERIOD") if the
                Parties have not entered into the Non-U.S. Territory Agreement
                by such time.

                3.4.3   AGREED TERMS. Momenta and the Sandoz Parties agree that
                the Non-U.S. Territory Agreement will (a) be generally
                consistent with the terms of this Agreement (PROVIDED, HOWEVER,
                THAT the Non-U.S. Territory Agreement will, unless otherwise
                agreed by Momenta and the applicable Sandoz Party, permit
                sublicensing of marketing rights, and, if sublicensing of
                marketing rights by a Sandoz Party is permitted, the Non-U.S.
                Territory Agreement shall include such Sandoz Party's payment to
                Momenta of a mutually agreed percentage of any payment received
                by the Sandoz Party from a sublicense of the Product; and
                PROVIDED FURTHER THAT the Non-U.S. Territory Agreement shall
                include provisions specific to the relevant countries and/or to
                inter-jurisdictional agreements, which may include, without
                limitation, provisions with respect to tax withholding and
                addressing legal restrictions on inter-jurisdictional payments,
                as applicable), (b) take into consideration the economics of the
                international markets for enoxaparin, and (c) not include
                upfront payments or Development-related milestone payments.

                3.4.4   NON-EXERCISE OF OPTION. If the Sandoz Parties elect not
                to exercise the Non-U.S. Option pursuant to Section 3.4.1 within
                the Non-U.S. Option Period, or elect to exercise the Non-U.S.
                Option with respect to only a portion of the Non-U.S. Territory,
                on a country-by-country basis, Momenta shall be free to begin
                discussions or negotiations and/or enter into any contract,
                agreement, understanding or arrangement with Third Parties
                relating to the Development and/or Commercialization of the
                Product in the Non-U.S. Territory or, if applicable, the portion
                of the Non-U.S. Territory as to which the Sandoz Parties did not
                exercise the Non-U.S. Option.

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                3.4.5   FAILURE TO REACH AGREEMENT; RIGHT OF FIRST REFUSAL. If a
                Sandoz Party exercises the Non-U.S. Option but Momenta and such
                Sandoz Party do not enter into the Non-U.S. Territory Agreement
                prior to the expiration of the Initial Non-U.S. Territory
                Negotiation Period, Momenta shall be free to begin discussions
                or negotiations with Third Parties relating to the Development
                and/or Commercialization of the Product in the portion of the
                Non-U.S. Territory for which a Sandoz Party has exercised the
                Non-U.S. Option; PROVIDED THAT Momenta will not enter into any
                contract, agreement, term sheet, understanding or arrangement
                with a Commercial Third Party relating to the Development and/or
                Commercialization of the Product in the portion of the Non-U.S.
                Territory for which such Sandoz Party has exercised the Non-U.S.
                Option without first complying with the following procedures: At
                such time as Momenta has reached agreement on key terms with a
                Third Party relating to the Development and/or Commercialization
                of the Product in the portion of the Non-U.S. Territory for
                which a Sandoz Party has exercised the Non-U.S. Option (a "THIRD
                PARTY TERM SHEET"), Momenta shall provide a copy of such Third
                Party Term Sheet (which may be redacted to delete the name of
                the Third Party) to the applicable Sandoz Party (a "THIRD PARTY
                TERM SHEET NOTICE"). Within [**] after receipt of a Third Party
                Term Sheet Notice, such Sandoz Party shall indicate in writing
                to Momenta whether it wishes to negotiate and enter into
                definitive agreements reflecting the terms set forth in the
                Third Party Term Sheet. If the Sandoz Party indicates within
                such [**] period that it wishes to negotiate and enter into
                definitive agreements, Momenta and such Sandoz Party shall in
                good faith negotiate definitive agreements reflecting the terms
                set forth in the Third Party Term Sheet. If, despite such good
                faith negotiations, Momenta and the Sandoz Party have not
                entered into such definitive agreements within [**] after such
                Sandoz Party's receipt of the Third Party Term Sheet Notice (as
                such period may be extended by mutual agreement of the Parties),
                then Momenta shall be free to negotiate and enter into
                definitive agreements reflecting the terms set forth in the
                Third Party Term Sheet with the applicable Third Party. Momenta
                shall not be obligated to reveal to the Sandoz Parties the
                identity of any Third Party involved in any such transaction.

                3.4.6   LICENSE TO MOMENTA. Momenta shall have the right to use
                any and all preclinical, clinical, technical and other relevant
                data, records, reports, information, materials and technology in
                its possession or in the possession of the Sandoz Parties (to
                the extent the Sandoz Parties have the right to transfer the
                foregoing to Momenta) (including, without limitation,
                manufacturing technology) that arises from and is used in the
                Collaborative Program (collectively, "PROGRAM OUTPUT") in its
                Development and Commercialization of the Product for any country
                in the Non-U.S. Territory with respect to which a Sandoz Party
                has not exercised the Non-U.S. Option prior to the expiration of
                the Non-U.S. Option Period and for any country in the Non-U.S.
                Territory with respect to which Momenta and a Sandoz Party have
                not executed the Non-U.S. Territory Agreement either prior to
                the expiration of the Initial Non-U.S. Territory Negotiation
                Period or pursuant to Section 3.4.5. In the event that any item
                of

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                Program Output constitutes Sandoz IP, the Sandoz Parties
                automatically grant to Momenta, upon the expiration of the
                Non-U.S. Option Period and/or the expiration of the Initial
                Non-U.S. Territory Negotiation Period, as applicable, a
                non-exclusive, sublicenseable, royalty-free license under such
                Sandoz IP to (a) Develop, make, have made, use, sell, offer to
                sell, lease, import and export the Product in the Field in any
                country in the Non-U.S. Territory with respect to which a Sandoz
                Party has not exercised the Non-U.S. Option prior to the
                expiration of the Non-U.S. Option Period and in any country in
                the Non-U.S. Territory with respect to which Momenta and a
                Sandoz Party have not executed the Non-U.S. Territory Agreement
                either prior to the expiration of the Initial Non-U.S. Territory
                Negotiation Period or pursuant to Section 3.4.5, and (b) make
                and have made the Product anywhere in the world for the purpose
                of sale of the Product in the Field into any country in the
                Non-U.S. Territory with respect to which a Sandoz Party has not
                exercised the Non-U.S. Option prior to the expiration of the
                Non-U.S. Option Period and into any country in the Non-U.S.
                Territory with respect to which Momenta and a Sandoz Party have
                not executed the Non-U.S. Territory Agreement either prior to
                the expiration of the Initial Non-U.S. Territory Negotiation
                Period or pursuant to Section 3.4.5. Program Output shall
                expressly exclude, and Momenta shall have no right to use or
                share with any Third Party, any financial information (other
                than total per-unit costs of the Product with no breakdown of
                the components thereof), that was created, generated or compiled
                pursuant to the Collaborative Program and otherwise pursuant to
                this Agreement. Nothing in this Section 3.4.6 shall be
                interpreted or construed to in any way license, authorize or
                otherwise permit Momenta or any Third Party to use any Program
                Output or practice any Sandoz IP in any manner that is
                inconsistent with the Sandoz Parties' rights under this
                Agreement.

        3.5.    EQUITY INVESTMENT. Momenta hereby grants to Sandoz a
non-exclusive option to invest between U.S.$5,000,000 and U.S.$10,000,000 in a
class of preferred stock of Momenta to be substantially equivalent to Momenta's
Series B Convertible Preferred Stock, U.S.$0.01 par value per share, at a
mutually agreed share price and subject to such obligations and restrictions,
and entitled to such rights and preferences, as those currently imposed and
bestowed on the holders of Momenta's Series B Convertible Preferred Stock. The
exercise of such option shall be subject to the execution of definitive
agreements containing the terms and conditions customary in such agreements and
the approval thereof by the respective boards of directors of Momenta and
Sandoz, and, to the extent applicable, by certain stockholders of Momenta. The
option granted by Momenta pursuant to this Section 3.5 shall expire unless such
definitive agreements are executed within ninety (90) days after the Effective
Date, as such date may be extended by mutual consent of Momenta and Sandoz. In
the event of the exercise by Sandoz of its option pursuant to this Section 3.5,
Momenta and Sandoz agree to negotiate such definitive agreements in good faith
and to use Commercially Reasonable Efforts to obtain all necessary approvals and
execute such definitive agreements prior to the expiration of such ninety-day
period.

        3.6.    SANDOZ AFFILIATES. The Sandoz Parties may permit any of their
Affiliates to exercise all or any portion of the rights of the Sandoz Parties
pursuant to this Article 3 and in

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such event, all applicable references to 'Sandoz,' a 'Sandoz Party' or the
'Sandoz Parties' shall be considered references to such Affiliate(s); PROVIDED
THAT any such Affiliate(s) agree to be bound by the restrictions and obligations
applicable to the Sandoz Parties pursuant to the applicable provisions of this
Article 3.

4.      FINANCIAL PAYMENTS

        4.1.    CAPPED COSTS. Subject to the provisions of this Agreement, BCWI
shall be responsible for all Development Costs and Sandoz shall be responsible
for all Legal Expenses incurred by the Parties in performing their obligations
under this Agreement, up to a maximum of an aggregate of such Development Costs
and Legal Expenses of U.S.$[**] (the "COST CAP"). Within thirty (30) days after
the end of each Quarter during this Agreement, the Sandoz Parties shall provide
to Momenta a written report documenting any Capped Costs incurred by the Sandoz
Parties during such just-ended Quarter. Within thirty (30) days after the end of
each Quarter during this Agreement, Momenta shall provide to the Sandoz Parties
an invoice (together with supporting documentation) for any Capped Costs
incurred by Momenta during such just-ended Quarter (which, with respect to the
first Quarter under this Agreement, shall include the Pre-Existing Costs), and
payments will be due to be made to Momenta by the applicable Sandoz Party(ies)
for any Capped Costs incurred by Momenta within forty-five (45) days of receipt
of such invoice. Capped Costs shall be incurred by the Parties according to the
Annual Collaboration Plan. Any material deviation from the Annual Collaboration
Plan shall immediately be reported to the Joint Steering Committee.

        4.2.    FTE FUNDING. Momenta will provide [**] FTEs during the [**]
period commencing October 1, 2003 under this Agreement and [**] FTEs during the
following [**] period under this Agreement, devoted exclusively to efforts on
behalf and in furtherance of the Collaborative Program. As compensation for the
provision of such FTEs, BCWI shall pay Momenta, effective as of October 1, 2003,
at the FTE Rate. Additional FTEs, as mutually agreed to in the applicable Annual
Collaboration Plan, will be provided by Momenta, and paid for by BCWI (subject
to the provisions of Section 4.11.8) at the FTE Rate ("ADDITIONAL FTE'S").
Within thirty (30) days after the end of each Quarter during such time periods,
Momenta shall provide to BCWI a report of the number of FTEs actually devoted by
Momenta to the Collaborative Program during such just-ended Quarter and payments
will be due by BCWI within forty-five (45) days after receipt of such report,
based on the number of FTEs actually committed by Momenta to the Collaborative
Program during such Quarter at the FTE Rate, PRO RATA for such actual number of
FTEs. Momenta shall track the number of FTEs devoted to the Collaborative
Program on a monthly basis in accordance with Momenta's standard record-keeping
practices (including without limitation the use of at a minimum monthly
timesheets) (the "FTE RECORDS").

        4.3.    EXCESS COSTS. Subject to the provisions of Sections 4.11.8 and
11.5 and SCHEDULE 4.3, Sandoz shall bear responsibility for all Excess Costs.
Within fifteen (15) days after the end of each Quarter during this Agreement,
Momenta shall provide to Sandoz an invoice (together with supporting
documentation) for any Excess Costs paid by Momenta during such just-ended
Quarter, and payments will be due to be made to Momenta by Sandoz for any Excess
Costs paid by Momenta within forty-five (45) days of receipt of such invoice.

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        4.4.    COMMERCIALIZATION COSTS. Sandoz shall be responsible for all
Commercialization Costs. Momenta shall bear no responsibility for the
Commercialization Costs.

        4.5.    U.S. PROFIT INTEREST. In the event that, at the time of U.S.
Launch, there [**] (the "[**]Period"), then, subject to the provisions of
Section 4.9, for each Post-Launch Quarter during such [**] Period during which
Sandoz, its Affiliates or distributors is selling the Product in the U.S.
Territory, Sandoz shall pay Momenta an amount computed by multiplying [**]
percent ([**]%) times the Profits in the U.S. Territory during such Post-Launch
Quarter (the "PROFIT INTEREST"), which shall be adjusted pursuant to SCHEDULE
4.3. The [**] Period shall automatically terminate upon the existence of [**]
the U.S. Territory and the provisions of this Section 4.5 shall not apply
thereafter.

        4.6.    U.S. POST-[**] ROYALTY.

                4.6.1   Upon termination of the [**] Period, Section 4.5 shall
                no longer apply. Subject to the provisions of Section 4.8, if
                such termination occurs after the [**] anniversary of the U.S.
                Launch, then, following such termination (subject to the
                provisions of Section 4.9), for each Post-Launch Quarter during
                which Sandoz, its Affiliates or distributors is selling the
                Product in the U.S. Territory (the "[**] PERIOD"), Sandoz shall
                pay Momenta a royalty (the "[**][**] ROYALTY") as a percentage
                of Net Sales of the Product in the U.S. Territory to be computed
                according to the following table, by multiplying Net Sales in
                the U.S. Territory for such Post-Launch Quarter times the
                applicable percentage listed in the following table:

<Table>
<Caption>
                        Net Sales in U.S. Territory
                        During a Post-Launch Year                      Royalty Rate
                        ---------------------------                    ------------
                        <S>                                               <C>
                        First U.S.$[**] Million in Net Sales in
                        the U.S. Territory                                [**]%

                        Over U.S.$[**] Million in Net Sales in
                        the U.S. Territory                                [**]%
</Table>

                4.6.2   The amounts payable under Section 4.6.1 shall be
                adjusted pursuant to SCHEDULE 4.3.

        4.7.    U.S. [**] ROYALTY.

                4.7.1   In the event that (a) at the time of U.S. Launch there
                are [**] or (b) termination of the [**] Period occurs on or
                before the [**] anniversary of the U.S. Launch (in which case,
                upon such termination the provisions of Section 4.5 shall no
                longer apply), then, subject to the provisions of Sections 4.8
                and 4.9, for each Post-Launch Quarter during which Sandoz, its
                Affiliates or distributors is selling the Product in the U.S.
                Territory (the "[**] PERIOD"), Sandoz shall pay Momenta a
                royalty (the "[**] ROYALTY") as a percentage of Net Sales of the
                Product in the

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                U.S. Territory to be computed according to the following table,
                by multiplying Net Sales in the U.S. Territory for such
                Post-Launch Quarter times the applicable percentage listed in
                the table:

<Table>
<Caption>
                        Net Sales in U.S. Territory During a
                        Post-Launch Year                               Royalty Rate
                        ------------------------------------           ------------
                        <S>                                               <C>
                        First U.S.$[**] Million in Net Sales in the
                        U.S. Territory                                    [**]%

                        Over U.S.$[**] Million in Net Sales in the
                        U.S. Territory                                    [**]%
</Table>

                4.7.2   The amounts payable under Section 4.7.1 shall be
                adjusted pursuant to SCHEDULE 4.3.

        4.8.    AVENTIS [**].

                4.8.1   If the [**] Period (i) terminates because there is [**],
                or (ii) never existed as a result of [**]; then (subject to the
                provisions of Section 4.9) thereafter until such time as there
                is [**] (the "Aventis [**]"), at which time the provisions of
                Section 4.6 or Section 4.7, as applicable, shall govern, Sandoz
                shall pay the Post-[**] Royalty during each Post-Launch Year (or
                portion thereof) until such time as the total Profits for the
                Product in the U.S. Territory for such Post-Launch Year (or
                portion thereof) equal the Aventis [**], and thereafter, solely
                with respect to any Profits exceeding the Aventis [**], during
                the remainder of such Post-Launch Year, Sandoz shall pay Momenta
                the Profit Interest with respect to such excess. The Aventis
                [**] shall automatically terminate upon the existence of [**] in
                the U.S. Territory and the provisions of this Section 4.8 shall
                not apply thereafter.

                4.8.2   The amounts payable under Section 4.8.1 shall be
                adjusted pursuant to SCHEDULE 4.3.

        4.9.    ALLOCATION BETWEEN PERIODS. In the event that a termination of
the [**] and/or the Aventis [**] falls on a day other than the first day of a
Post-Launch Quarter, the Profit Interest and Post-[**] Royalty or [**] Royalty,
as the case may be, for such Post-Launch Quarter shall be paid for such
Post-Launch Quarter based upon the actual Net Sales made during such Post-Launch
Quarter under the [**] Period, the Aventis [**] and/or the Post-[**] Royalty
Period or [**] Royalty Period, as the case may be.

        4.10.   MILESTONE PAYMENTS.

                4.10.1  REGULATORY MILESTONE PAYMENT. The Sandoz Parties shall
                pay Momenta a one-time non-creditable, non-refundable milestone
                payment equal to [**] Dollars (U.S.$[**]) ("REGULATORY MILESTONE
                PAYMENT") on the earlier of (a) Final Legal Clearance or (b)
                U.S. Launch; PROVIDED, HOWEVER, THAT the Regulatory Milestone
                Payment is payable only if (i) Sandoz receives ANDA Final
                Approval for an

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                ANDA filed by Sandoz or any of its Affiliates for the Product
                before any Third Party (other than [**]) receives ANDA Final
                Approval for an ANDA filed by such Third Party for a
                Lovenox(R)-Equivalent Product, and (ii) (A) if U.S. Launch
                occurs prior to Final Legal Clearance, there is [**] in the U.S.
                Territory at the time of U.S. Launch, or (B) if Final Legal
                Clearance occurs prior to U.S. Launch, no Third Party (other
                than [**]) has received ANDA Final Approval for an ANDA filed by
                such Third Party for a Lovenox(R)-Equivalent Product at the time
                of Final Legal Clearance.

                4.10.2  COMMERCIAL MILESTONE PAYMENTS.

                a.      The Sandoz Parties shall pay Momenta the following
                        milestone payments (the "FULL MILESTONE PAYMENTS") (as
                        shall be adjusted pursuant to SCHEDULE 4.3, the
                        "COMMERCIAL MILESTONE PAYMENTS"); PROVIDED THAT each
                        such milestone payment shall be payable only if (i)
                        Sandoz has sold the Product during the twelve (12)
                        months immediately preceding the events described below,
                        or Sandoz's failure to sell the Product during such
                        period is a breach of this Agreement, and (ii) as of
                        each anniversary described below, there is [**] in the
                        U.S. Territory:

<Table>
<Caption>
                                 Milestone Event              Amount of Milestone
                                 --------------               -------------------
                        <S>                                        <C>
                        [**] anniversary of U.S. Launch            U.S.$[**]
                        [**] anniversary of U.S. Launch            U.S.$[**]
                        [**] anniversary of U.S. Launch            U.S.$[**]
                        [**] anniversary of U.S. Launch            U.S.$[**]
                        [**] anniversary of U.S. Launch            U.S.$[**]
</Table>

                b.      Each Commercial Milestone Payment shall be made within
                        forty-five (45) days after the end of the applicable
                        Post-Launch Quarter in which the Milestone Event
                        referenced in the above table occurs; PROVIDED, HOWEVER,
                        that if any Milestone Event occurs prior to Final Legal
                        Clearance, the applicable Commercial Milestone Payment
                        for such Milestone Event shall be made within forty-five
                        (45) days after the end of the Post-Launch Quarter in
                        which Final Legal Clearance occurs. For purposes of this
                        Agreement, each such Post-Launch Quarter when a
                        Commercial Milestone Payment is actually made shall be a
                        "MILESTONE PAYMENT QUARTER". For example, if Final Legal
                        Clearance occurs midway between the [**] and [**]
                        anniversary of U.S. Launch, the first two (2) Commercial
                        Milestone Payments shall be due 45 days after the end of
                        the Post-Launch Quarter in which Final Legal Clearance
                        occurs. For the avoidance of doubt, if Final Legal
                        Clearance does not occur during the Term, no Commercial
                        Milestone Payment(s) shall be due to Momenta.

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        4.11.   PAYMENT/ACCOUNTING.

                4.11.1  TIME AND MANNER OF PAYMENT OF ROYALTIES. The Sandoz
                Parties (and/or Momenta in the event Section 11.6.3 applies)
                shall report the amount of Product sold in each Post-Launch
                Quarter, the gross amount invoiced, the deductions used in the
                calculation of Net Sales, the applicable Manufacturing Costs and
                the resulting calculation of Profit Interest or royalties due to
                Momenta (or the Sandoz Parties, as applicable), within
                forty-five (45) days after the end of such Post-Launch Quarter.
                With each such report, the Sandoz Parties (or Momenta, as
                applicable) shall pay the amount of Profit Interest or royalties
                due. If no Profit Interest or royalties are due, the report
                shall so state. Reports shall provide a reconciliation showing
                the amount due.

                4.11.2  COMPUTATION. All payments due shall be payable in United
                States dollars. Such payments shall be without deduction of
                exchange, collection, or other charges, and, specifically,
                without deduction of withholding or similar taxes or other
                government imposed fees or taxes, except as otherwise permitted
                in the definition of "Net Sales" or by this Section 4.11.

                4.11.3  INTEREST. Interest shall be payable on the aggregate
                amount of any payments that are not paid on or before the date
                such payments are due under this Agreement at a rate per annum
                equal to the lesser of (a) two percentage points above the prime
                rate of interest, as reported by THE WALL STREET JOURNAL for the
                applicable period, or (b) the highest rate permitted by
                applicable law, in each case calculated on the number of days
                such payments are paid after the date they are due.

                4.11.4  RECORD KEEPING. The Sandoz Parties and Momenta shall
                keep, and shall require their Affiliates, distributors,
                licensees and sublicensees to keep, accurate and complete
                accounting records of the Products sold under this Agreement
                ("PRODUCT RECORDS") appropriate to determine the amount of
                Profit Interest or royalties due hereunder and to support the
                reports made pursuant to Section 4.11.1. Such records shall be
                retained for at least five (5) years following a given reporting
                period.

                4.11.5  SANDOZ AUDIT. Upon sixty (60) days' prior written
                notice, the Sandoz Parties shall permit their books and records
                of Capped Costs, Excess Costs and Product Records to be examined
                for a particular calendar year, no more than once annually,
                during normal business hours, by an independent auditor
                appointed by Momenta and reasonably acceptable to the Sandoz
                Parties, and at Momenta's expense, to the extent necessary to
                verify the accuracy of the Profit Interest and royalty reports
                delivered by the Sandoz Parties under this Agreement. Any
                information received as a result of such inspection shall be
                maintained as the Sandoz Parties' Confidential Information.

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                4.11.6  MOMENTA AUDIT. Upon sixty (60) days' prior written
                notice, Momenta will permit its books and records of Capped
                Costs, Excess Costs, the FTE Records and Product Records to be
                examined for a particular calendar year, no more than once
                annually, during normal business hours, by an independent
                auditor appointed by Sandoz (on behalf of itself and BCWI) and
                reasonably acceptable to Momenta, and at Sandoz's expense, to
                the extent necessary to verify the accuracy of the invoices and
                royalty reports delivered by Momenta under this Agreement. Any
                information received as a result of such inspection shall be
                maintained as Momenta's Confidential Information.

                4.11.7  UNDERPAYMENT/OVERPAYMENT AND PAYMENT DISPUTES. In the
                event an examining auditor specified in Sections 4.11.5 or
                4.11.6 concludes that an underpayment or overpayment was made,
                the auditor will specify such in a written report along with the
                information on which such conclusion is based. This report will
                be shared promptly with the audited Party. The amount of any
                such underpayment or the reimbursement of any such overpayment
                shall be due and payable by the audited Party within forty-five
                (45) days of the date of such report, PROVIDED THAT if a Party
                disputes the conclusion of the auditor, the Parties will resolve
                the dispute according to Article 13. If the underpayment by the
                audited Party or the overpayment by the auditing Party differs
                by greater than five percent (5%) from the amount that was
                otherwise due, the audited Party shall pay all of the costs of
                such review, together with interest calculated on the amount of
                such underpayment or overpayment in the manner provided in
                Section 4.11.3.

                4.11.8  RELATIONSHIP BETWEEN THE SANDOZ PARTIES. As between
                Sandoz and BCWI, (a) BCWI shall bear responsibility for all
                Development Costs to the extent such Development Costs are part
                of Capped Costs and for FTE costs for the first fifteen (15)
                FTEs in accordance with Section 4.2; (b) Sandoz shall bear
                responsibility for all payments under Sections 4.3, 4.4, 4.5,
                4.6, 4.7 and 4.8, unless Sandoz otherwise makes arrangements
                with BCWI for any such payments; and (c) the Sandoz Parties
                shall bear responsibility for all payments under Section 4.10.
                Sandoz and BCWI are permitted to enter into an agreement between
                themselves pursuant to which each Sandoz Party shall bear its
                portion of the Profit Interest and royalties due to Momenta
                pursuant to this Agreement and for payment of Development Costs
                that are part of Excess Costs and for Additional FTEs. Sandoz
                shall guarantee all obligations of BCWI under this Agreement,
                other than those obligations guaranteed by Sandoz GmbH, as set
                forth on the signature page of this Agreement.

        4.12.   TRUE-UP. Notwithstanding any other provision of this Agreement,
the Parties agree that for a two-year period after the end of the Term, the
Sandoz Parties shall submit to Momenta, on a quarterly basis within forty-five
(45) days following the close of each Quarter, a schedule showing any adjustment
to the calculations of the Profits from the Product and Net Sales, and the
resulting adjustment to payments made to Momenta hereunder, which occurred in
such Quarter, and the Party owing any amounts pursuant to such reconciliation
shall, within forty-five (45) days of the receipt of such reconciliation, submit
payment to the other Party.

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5.      JOINT DEVELOPMENT AND COMMERCIALIZATION

        5.1.    JOINT COLLABORATION. Sandoz and Momenta, and, to the extent
appropriate, BCWI, shall jointly collaborate in the Development and
Commercialization of the Product and the Legal Activities, using Commercially
Reasonable Efforts to Develop the Product, to achieve Legal Clearance, to bring
the Product to the market in the U.S. Territory within a commercially reasonable
time period (subject to the provisions of Section 6.2.1) and to Commercialize
the Product in the U.S. Territory. Sandoz shall be responsible for ensuring that
representatives of BCWI participate in the Development and Commercialization
activities and the Legal Activities as appropriate.

        5.2.    JOINT PROJECT TEAM. The Development and Commercialization
activities and Legal Activities shall be conducted and managed on a day-to-day
basis through a Joint Project Team ("JOINT PROJECT TEAM" or "JPT"). Momenta and
Sandoz shall each appoint one (1) Project Leader promptly following the
Effective Date and may change its Project Leader at any time by giving written
notice to the other. The JPT shall consist of three (3) (or such other mutually
agreed number) representatives from each of Sandoz and Momenta (including each
Party's then-current Project Leader), which representatives shall be directly
involved with and responsible for Development and Commercialization activities
and Legal Activities. Promptly after the Effective Date, Momenta and Sandoz
shall each appoint its representatives to the JPT. Momenta and Sandoz may each
change its JPT representatives at any time by giving written notice to the
other. The JPT shall meet within thirty (30) days after the Effective Date and,
thereafter, at least quarterly during the course of the Collaborative Program.
Additional representatives of a Party may attend meetings of the JPT on an AD
HOC invited basis as appropriate.

        5.3.    JPT RESPONSIBILITIES. Except as provided in Sections 5.10, 6.1
and 6.2.1, the JPT shall be responsible for: (a) directing all day-to-day
aspects of the Development and Commercialization of, and the Legal Activities
with respect to, the Product; (b) preparing and submitting to the Joint Steering
Committee ("JOINT STEERING COMMITTEE" or "JSC") an Annual Collaboration Plan for
each Contract Year; (c) discussing and resolving ongoing issues; and (d)
periodically reporting to the JSC and referring any disputes not resolved by the
JPT to the JSC for resolution. The JPT shall only act unanimously and each
Party, acting through its representatives, shall have one vote on the JPT.
Within thirty (30) days after each meeting, the Project Leaders will jointly
provide the JSC with a written report describing, in reasonable detail, the
status of the Collaborative Program and the Development and Commercialization
of, and Legal Activities with respect to, the Product, including, without
limitation, a summary of the results and progress to date, the status of the
then-current budget in the Annual Collaboration Plan (actuals vs. estimates),
project timelines, critical path issues and any other issues requiring
resolution, proposed solutions to such issues, and the agreed resolution of
previously reported issues.

        5.4.    JOINT STEERING COMMITTEE. The JSC shall consist of six (6)
members, three (3) representatives from each of Sandoz and Momenta, each of whom
shall have experience and seniority sufficient to enable him or her to make
decisions on behalf of the Party he or she represents. Promptly after the
Effective Date, Momenta and Sandoz shall each appoint its

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representatives to the JSC. Momenta and Sandoz may each change its JSC
representatives at any time by giving written notice to the other.

        5.5.    JSC ADMINISTRATION. The JSC shall appoint a chairperson from
among its members, which shall rotate annually between the representatives from
Sandoz and the representatives from Momenta. The chairperson shall be
responsible for calling meetings of the JSC and for leading the meetings. A JSC
member of the Party hosting a meeting of the JSC (or someone designated by the
JSC) shall serve as secretary of that meeting. The secretary of the meeting
shall prepare and distribute to all members of the JSC draft minutes of the
meeting within thirty (30) days following the meeting to allow adequate review
and comment. Such minutes shall provide a description in reasonable detail of
the discussions held at the meeting and a list of any actions, decisions or
determinations approved by the JSC. Minutes of each JSC meeting shall be
approved or disapproved, and revised as necessary, at the next meeting. Final
minutes of each meeting shall be distributed to the members of the JSC by the
chairperson.

        5.6.    JSC MEETINGS. The location of meetings of the JSC shall
alternate between Sandoz's principal place of business and Momenta's principal
place of business, or as otherwise agreed by the Parties. The JSC may also meet
by means of a telephone conference call or videoconference. Each Party shall use
reasonable efforts to cause its representatives to attend the meetings of the
JSC. If a representative of a Party is unable to attend a meeting, such Party
may designate an alternate to attend such meeting in place of the absent
representative. In addition, each of Momenta and Sandoz may, at its discretion,
invite non-voting employees, and, with the consent of Sandoz and Momenta,
respectively, consultants or scientific advisors, to attend the meetings of the
JSC to, among other things, review and discuss the Collaborative Program and its
results. Either Momenta or Sandoz may convene a special meeting of the JSC for
the purpose of resolving disputes.

        5.7.    JSC RESPONSIBILITIES. Except as provided in Sections 5.10, 6.1
and 6.2.1, the JSC shall be responsible for: (a) overseeing the Development and
Commercialization activities and Legal Activities under the Collaborative
Program (including, without limitation, (i) determining the strategy to achieve
Legal Clearance, such as the decision regarding which Locked Manufacturing
Process to employ, (ii) determining the enforcement strategy with respect to the
Joint Collaboration IP, and (iii) determining the patent prosecution and
enforcement strategy with respect to those Product-Specific Patent Rights
relevant to the exercise by Sandoz of the licenses granted in Section 2.1); (b)
providing overall guidance to the JPT; (c) approving the Annual Collaboration
Plan or any changes thereto, including without limitation, the budget contained
therein pursuant to Section 5.8 and any changes thereto; (d) reviewing progress
toward milestones in the Annual Collaboration Plan; (e) attempting to resolve
disputes; and (f) performing such other tasks and undertaking such other
responsibilities as are set forth in this Agreement. The JSC shall only act
unanimously and each of Momenta and Sandoz, acting through its representatives,
shall have one vote on the JSC. The JSC shall meet within thirty (30) days after
the Effective Date and, thereafter, at least quarterly during the course of the
Collaborative Program. Within thirty (30) days after each meeting, the persons
appointed by the JSC will provide Sandoz (on behalf of Sandoz and BCWI) and
Momenta with a written report describing, in reasonable detail, the status of
the Collaborative Program and the Development and Commercialization of, and
Legal Activities with respect to, the Product, a summary of the

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results and progress to date, any issues requiring resolution, and the agreed
resolution of previously reported issues. Disputes shall be resolved pursuant to
Article 13.

        5.8.    ANNUAL COLLABORATION PLAN. The Parties shall undertake the
Collaborative Program in accordance with the Annual Collaboration Plans. The JPT
shall prepare the Annual Collaboration Plan (a) for the First Contract Year
within thirty (30) days after the Effective Date, (b) for the Second Contract
Year at least sixty (60) days prior to the commencement of such Contract Year,
and (c) for the Third Contract Year and subsequent Contract Years at least
ninety (90) days prior to the commencement of such Contract Year. The JSC shall
review and approve the Annual Collaboration Plan (i) for the First Contract Year
within forty-five (45) days after the Effective Date, (ii) for the Second
Contract Year at least thirty (30) days prior to the commencement of such
Contract Year, and (iii) for the Third Contract Year and subsequent Contract
Years at least sixty (60) days prior to the commencement of such Contract Year.
The JPT shall prepare, and the JSC shall review and approve, updates and
amendments, as appropriate, to the then-current Annual Collaboration Plan during
the course of the applicable Contract Year. Each Annual Collaboration Plan shall
be consistent with the other terms and conditions of this Agreement. Each Annual
Collaboration Plan shall specify, among other things, (A) specific objectives of
the Collaborative Program during the applicable Contract Year, (B) specific
activities to be performed by each Party, or by Third Parties, in support of the
Collaborative Program during the applicable Contract Year, and (C) a budget
reflecting the resources (including FTEs) to be assigned and amounts expended by
each Party in support of the Collaborative Program. In particular, to support
the Development and Commercialization of, and Legal Activities with respect to,
the Product, the Annual Collaboration Plan shall specify the activities to be
performed by each Party, or by Third Parties, and the related resources
(including FTEs) to be assigned and the strategic marketing plan for the Product
in the U.S. Territory. In preparing the initial Annual Collaboration Plan, the
JPT shall assign specific activities to the relevant Party(ies). While all
activities will be considered joint activities within the collaboration, the JPT
shall assign specific activities to the relevant Party(ies) to execute. SCHEDULE
5.8 provides a preliminary list of activities to be included in the Annual
Collaboration Plan, along with a preliminary assignment of the Party(ies)
responsible for each activity. The Annual Collaboration Plan, to be approved by
the JSC, will include a complete list of activities and the assignment of the
relevant Party(ies) for each such activity. While a given Party may be assigned
the lead responsibility for an activity, it will be the responsibility of such
Party to achieve cross-company alignment on the strategy and the plans to
complete the activity consistent with the integrated strategy as defined in the
Annual Collaboration Plan.

        5.9.    COMPLIANCE WITH LAWS. Each Party agrees to use Commercially
Reasonable Efforts to carry out all work assigned to such Party in the Annual
Collaboration Plan and its other obligations under this Agreement in material
compliance with all applicable federal, state or local laws, regulations and
guidelines governing the conduct of such work, including, without limitation,
(a) the FD&C Act and any applicable implementing regulations; (b) cGMPs; (c) all
other applicable FDA guidelines; (d) all other applicable laws, including all
applicable U.S., federal, state, foreign and local environmental, health and
safety laws in effect at the time and place of manufacture of a Product; and (e)
all applicable export and import control laws.

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        5.10.   LEGAL CLEARANCE. Sandoz shall have sole responsibility to make
decisions with respect to Legal Clearance (except with respect to the
determination of whether Legal Clearance has occurred, which shall be determined
in accordance with the definitions herein of District Court Legal Clearance and
Final Legal Clearance); PROVIDED THAT such decisions are generally consistent
with the strategy set therefor by the JSC, and subject to the provisions of
Section 13.2.

6.      COMMERCIALIZATION BY SANDOZ

        6.1.    REVIEW AND OVERSIGHT. Other than with respect to Section 6.2.1,
which shall be in the sole discretion of Sandoz, all responsibilities of the
Parties with respect to Commercialization of the Product shall be subject to the
oversight and review of the Joint Project Team and the Joint Steering Committee
as set forth in Article 5. Notwithstanding Section 5.8 or any other provision of
this Agreement, Sandoz and its Affiliates (or, with respect to Section 11.6.1,
Momenta, its Affiliates and sublicensees) shall have the sole discretion and
exclusive authority to set the prices for the Product sold to Third Parties. The
Parties shall agree upon the trademark to be used for the Product, which shall
not include any trademark or tradename or a part thereof that uses the name
"Novartis" or "Sandoz" or a derivative thereof or any other trademark or part or
derivative thereof that is the name or derivative of a name of any other Sandoz
Affiliate.

        6.2.    PRE FINAL LEGAL CLEARANCE LAUNCH.

                6.2.1   Notwithstanding any other provision in this Agreement,
                the Parties agree that, if ANDA Final Approval for an ANDA filed
                by Sandoz or any of its Affiliates for the Product has been
                obtained and a District Court Decision has been obtained but
                Final Legal Clearance has not yet been obtained, Sandoz may, in
                its sole discretion, decide whether to proceed with U.S. Launch,
                or to defer U.S. Launch until Final Legal Clearance. Upon
                deciding to proceed with Pre Final Legal Clearance Launch,
                Sandoz shall promptly notify Momenta of such decision and shall
                use Commercially Reasonable Efforts to Commercialize the
                Product.

                6.2.2   Notwithstanding anything else herein to the contrary,
                the Parties agree that, consistent with the provisions of
                Section 12.1(c), Sandoz shall bear, and Momenta shall not be
                responsible for, any damages of Aventis in the event that Sandoz
                or its Affiliates are held liable for [**] under Patent
                Litigation, other than with respect to Momenta's responsibility
                for a portion of Settlement Costs pursuant to the provisions of
                Section 4.3.

7.      REGULATORY MATTERS

        7.1.    REVIEW AND OVERSIGHT. All responsibilities under this Article 7
shall be subject to the review and oversight of the Joint Project Team and the
Joint Steering Committee as set forth in Article 5.

        7.2.    ANDA FILING. Sandoz shall file an ANDA for the Product in
accordance with the Annual Collaboration Plans. The ANDA for the Product shall
be filed with the FDA by Sandoz under Sandoz's name. If the ANDA for the Product
includes a certification pursuant to 21

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U.S.C. 355(b)(2)(iv) or 355(j)(2)(A)(vii), Sandoz shall also provide to the
applicable Aventis Person notice, as required by 21 USC Section 355(b)(3) or 21
U.S.C. Section 355(j)(2)(B), respectively.

        7.3.    OWNERSHIP OF THE ANDAs. Sandoz shall own all ANDAs for the
Product and all rights in all data supporting the ANDAs for the Product.

        7.4.    ANDA RESPONSIBILITY. The JSC shall determine the
responsibilities of each Party with respect to the preparation of the ANDAs for
the Product and related activities.

        7.5.    REGULATORY INTERACTION. The JSC shall determine the
responsibilities of each Party with respect to interactions with the FDA with
respect to the Product; PROVIDED, HOWEVER, THAT Sandoz shall interact with the
FDA with respect to adverse event reporting obligations.

8.      INTELLECTUAL PROPERTY

        8.1.    OWNERSHIP.

                8.1.1   SINGLE OWNERSHIP. As between Momenta and the Sandoz
                Parties, the Sandoz Parties shall own all Sandoz IP and Momenta
                shall own all Momenta IP. Momenta hereby assigns to the Sandoz
                Parties all right, title and interest in and to any Improvements
                to Sandoz Know-How or Improvements to Sandoz Collaboration
                Know-How that are conceived and reduced to practice or developed
                solely by Momenta or its Affiliates, or jointly by a Sandoz
                Party or its Affiliates, on the one hand, and by Momenta or its
                Affiliates, on the other hand, during, and in the conduct of,
                the Collaborative Program ("MOMENTA ASSIGNED IMPROVEMENTS").
                Each of Sandoz and BCWI hereby assigns to Momenta all right,
                title and interest in and to any Improvements to Momenta
                Know-How or Improvements to Momenta Collaboration Know-How that
                are conceived and reduced to practice or developed solely by
                Sandoz or BCWI, or jointly by Sandoz or BCWI, on the one hand,
                and by Momenta or its Affiliates, on the other hand, during, and
                in the conduct of, the Collaborative Program ("SANDOZ ASSIGNED
                IMPROVEMENTS"). The assigning Party shall execute all documents
                necessary to effectuate this Section 8.1.1. Notwithstanding
                anything to the contrary herein, BCWI, with respect to the
                Sandoz IP, and Momenta, with respect to the Momenta IP, shall
                have the right to assign the Sandoz IP, in the case of BCWI, or
                the Momenta IP, in the case of Momenta, to its respective
                Affiliates, without the consent of the other Party, or to Third
                Parties, with the consent of the other Party, such consent not
                to be unreasonably withheld, so long as any such assignment
                pursuant to this sentence is subject to the licenses granted
                pursuant to this Agreement and is otherwise consistent with this
                Agreement.

                8.1.2   Momenta hereby grants to Sandoz and BCWI an irrevocable,
                perpetual, non-exclusive, royalty-free, sublicensable license to
                practice the Sandoz Assigned Improvements outside of the Field.
                Each Sandoz Party hereby grants to Momenta an irrevocable,
                perpetual, non-exclusive, royalty-free, sublicensable license to
                practice the Momenta Assigned Improvements outside of the Field.

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                8.1.3   JOINT OWNERSHIP. All Joint Collaboration IP shall be
                owned jointly on the basis of an undivided one-half interest by
                BCWI and Momenta. Notwithstanding anything to the contrary
                herein, BCWI and Momenta shall each have the right to sell,
                license or otherwise transfer such Joint Collaboration IP to its
                Affiliates or any Third Party without the consent of the other
                Party so long as such sale, license or transfer is subject to
                the licenses granted pursuant to this Agreement and is otherwise
                consistent with this Agreement.

                8.1.4   INVENTORSHIP. Inventorship shall be determined by the
                Parties in good faith in accordance with relevant patent laws.
                In the event of a dispute regarding inventorship or the
                ownership of Collaboration Know-How that the Parties are unable
                to resolve, mutually acceptable outside patent counsel not
                regularly employed by any Party or their Affiliates shall be
                retained to resolve such dispute.

                8.1.5   POLICIES. In order to protect the Parties' Patent Rights
                under United States laws in any inventions conceived or reduced
                to practice during or as a result of the Collaborative Program,
                each Party agrees to maintain a policy that requires its
                employees, individual contractors, consultants and agents to
                record and maintain all data and information developed in the
                course of the Collaborative Program in such a manner as to
                enable the Parties to use such records to establish the earliest
                date of conception, invention and/or to document diligent
                reduction to practice. At a minimum, the policy shall require
                such individuals to record all inventions generated by them in
                standard laboratory notebooks that are dated and corroborated by
                non-inventors on a regular, contemporaneous basis.

        8.2.    PATENT PROSECUTION.

                8.2.1   MOMENTA PATENT RIGHTS. Subject to any contractual
                obligations to, or restrictions imposed by, Momenta's Third
                Party licensors, Momenta shall use Commercially Reasonable
                Efforts to timely prepare, file, prosecute and maintain, at its
                expense, Momenta Patent Rights and Momenta Collaboration Patent
                Rights (in each case, other than any Product-Specific Patent
                Rights relevant to the exercise by the Sandoz Parties of the
                licenses granted in Section 2.1) in the United States and
                throughout the world.

                8.2.2   SANDOZ PATENT RIGHTS. Subject to any contractual
                obligations to, or restrictions imposed by, the Sandoz Parties'
                Third Party licensors, the Sandoz Parties shall use Commercially
                Reasonable Efforts to timely prepare, file, prosecute and
                maintain, at its expense, Sandoz Patent Rights and Sandoz
                Collaboration Patent Rights (in each case, other than any
                Product-Specific Patent Rights relevant to the exercise by the
                Sandoz Parties of the licenses granted in Section 2.1) in the
                United States and throughout the world.

                8.2.3   JOINT PATENT RIGHTS. Subject to any contractual
                obligations to, or restrictions imposed by, the Parties' Third
                Party licensors, the JSC shall make all decisions regarding
                whether and how to file, prosecute and maintain any Joint

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                Collaboration Patent Rights (other than any Product-Specific
                Patent Rights), including without limitation, the ability of
                Momenta or a Sandoz Party, as the case may be, to assume control
                of the filing, prosecution or maintenance of such Joint
                Collaboration Patent Rights in the name of the Sandoz Parties or
                Momenta, respectively, if the Sandoz Parties or Momenta,
                respectively, decline to file, prosecute or maintain such Joint
                Collaboration Patent Rights, elect to allow any such Joint
                Collaboration Patent Rights to lapse or elect to abandon any
                such Joint Collaboration Patent Rights before all appeals within
                the respective patent office have been exhausted; PROVIDED,
                HOWEVER, THAT, in the event of a dispute with respect to such
                decisions that the Parties are unable to resolve, mutually
                acceptable outside patent counsel not regularly employed by any
                Party or their Affiliates shall be retained to resolve such
                dispute.

                8.2.4   PRODUCT-SPECIFIC PATENT RIGHTS. Subject to any
                contractual obligations to, or restrictions imposed by, the
                Parties' Third Party licensors, the JSC shall make all decisions
                regarding whether and how to file, prosecute and maintain any
                Product-Specific Patent Rights relevant to the exercise by the
                Sandoz Parties of the licenses granted in Section 2.1, including
                without limitation, the ability of Momenta or a Sandoz Party, as
                the case may be, to assume control of the filing, prosecution or
                maintenance of such Product-Specific Patent Rights of the Sandoz
                Parties or Momenta, respectively, in the name of the Sandoz
                Parties or Momenta, respectively, if the Sandoz Parties or
                Momenta, respectively, decline to file, prosecute or maintain
                such Product-Specific Patent Rights, elect to allow any such
                Product-Specific Patent Right to lapse or elect to abandon any
                such Product-Specific Patent Right before all appeals within the
                respective patent office have been exhausted; PROVIDED, HOWEVER,
                THAT, in the event of a dispute with respect to such decisions
                that the Parties are unable to resolve, mutually acceptable
                outside patent counsel not regularly employed by any Party or
                their Affiliates shall be retained to resolve such dispute.

                8.2.5   COOPERATION AND ASSISTANCE. The Parties agree to
                cooperate with each other and render all reasonable assistance
                as may be necessary to support any patent application filed by
                another Party under this Section 8.2, including, but not limited
                to, consulting and coordinating with each other on any such
                patent filing activities to ensure that any Patent Rights or
                Confidential Information are not unduly compromised.

        8.3.    PARTICIPATION OF OTHER PERSONS.

                8.3.1   Each of the Sandoz Parties and Momenta shall be
                responsible for executing an appropriate agreement with each
                employee, individual contractor, consultant or agent (including,
                for purposes of clarity, individuals who regularly work for
                Affiliates of the Sandoz Parties or Momenta) working on their
                respective behalves on the Collaborative Program, including a
                provision requiring such employee, individual contractor,
                consultant or agent to assign to a Sandoz Party or Momenta,
                respectively, all Know-How and Patent Rights which he or she

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                develops or conceives and/or reduces to practice during his or
                her work on the Collaborative Program so that such Know-How and
                Patent Rights are Controlled by such Sandoz Party or Momenta,
                respectively.

                8.3.2   In the event that a Sandoz Party elects to contribute
                any Know-How of an Affiliate of such Sandoz Party and any
                associated Patent Rights to the Collaborative Program, such
                Sandoz Party shall be responsible for executing an appropriate
                agreement with such Affiliate requiring such Affiliate to assign
                to such Sandoz Party, or to exclusively license to such Sandoz
                Party in the Field, all such Know-How and/or Patent Rights so
                that such Know-How and/or Patent Rights are Controlled by such
                Sandoz Party. For purposes of clarity, the decision whether or
                not to contribute any such Know-How and associated Patent Rights
                for use in the Collaborative Program shall be in the sole
                discretion of such Sandoz Party.

                8.3.3   Except as the Parties may otherwise agree in writing,
                each of the Sandoz Parties and Momenta shall be responsible for
                executing an appropriate agreement with each Affiliate or Third
                Party contracting entity working on their respective behalves on
                the Collaborative Program, including a provision requiring such
                entity to assign to such Sandoz Party or Momenta, respectively,
                or exclusively license to such Sandoz Party or Momenta,
                respectively, in the Field, all Know-How and Patent Rights with
                respect to the Field which such entity develops or conceives
                and/or reduces to practice during its work on the Collaborative
                Program so that such Know-How and Patent Rights are Controlled
                by such Sandoz Party or Momenta, respectively.

                8.3.4   Each Party shall use Commercially Reasonable Efforts to
                enforce the terms of their respective agreements described in
                Sections 8.3.1, 8.3.2 and 8.3.3.

        8.4.    ENFORCEMENT OF NON-PRODUCT-SPECIFIC PATENT RIGHTS.

                8.4.1   INITIAL RIGHTS. Subject to any contractual obligations
                to, or restrictions imposed by, its Third Party licensors, the
                Owning Party shall have the initial right, but not the
                obligation, to institute an infringement action or take other
                appropriate action that it believes is reasonably required to
                protect the Owning Party's IP (other than any Product-Specific
                Patent Rights relevant to the exercise by the Sandoz Parties of
                the licenses granted in Section 2.1) from infringement in the
                Field, when, from its own knowledge or upon notice from another
                Party, the Owning Party becomes aware of the reasonable
                probability that such infringement exists in the Field. With
                respect to infringement in the Field in the U.S. Territory, the
                Non-Owning Party may at any time join in any infringement action
                brought by the Owning Party and may be represented by counsel of
                its choice, but control of such action shall remain with the
                Owning Party. Each other Party shall join in any infringement
                action as a party at the Owning Party's request in the event
                that an adverse party asserts, or the Owning Party determines in
                good faith, that a court lacks jurisdiction based on such other
                Party's absence as a party in such suit.

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                8.4.2   STEP-IN RIGHTS. Subject to any contractual obligations
                to, or restrictions imposed by, the Owning Party's Third Party
                licensors, in the event that the Owning Party shall not, within
                six (6) months of written notice from another Party of a
                suspected infringement of the Owning Party's IP (other than any
                Product-Specific Patent Rights relevant to the exercise by the
                Sandoz Parties of the licenses granted in Section 2.1) by a
                Third Party making, using, selling, offering to sell or
                importing a product in the Field in the U.S. Territory, commence
                and vigorously pursue an action to enjoin such infringement, the
                Non-Owning Party shall be entitled, at its expense, to commence
                the action in its name; PROVIDED, HOWEVER, THAT the Non-Owning
                Party shall consult with the Owning Party with respect to such
                action and shall give due consideration to the Owning Party's
                advice and the Owning Party's intellectual property protection
                strategy. The Owning Party shall join in any infringement action
                as a party, at the request of the Non-Owning Party, in the event
                that the court rules or other laws then applicable shall require
                the joinder of the Owning Party as the owner of the Owning
                Party's IP (other than any Product-Specific Patent Rights
                relevant to the exercise by the Sandoz Parties of the licenses
                granted in Section 2.1) for purposes of prosecuting such
                infringement action, but shall have no obligation to actively
                participate or incur expenses beyond the minimum level necessary
                to appear for the purpose of sustaining jurisdiction.

                8.4.3   COSTS. Each Party shall assume and pay all of its own
                out-of-pocket costs incurred in connection with any litigation
                or proceedings described in this Section 8.4, including, without
                limitation, the fees and expenses of such Party's counsel.

                8.4.4   RECOVERIES. Subject to any contractual obligations to,
                or restrictions imposed by, the Owning Party's Third Party
                licensors, any recovery obtained by a Party(ies) as a result of
                any proceeding described in this Section 8.4 or from any
                counterclaim or similar claim asserted in a proceeding described
                in Section 8.5, by settlement or otherwise, shall be applied as
                follows:

                        a.      First, to reimburse each Party for all
                                litigation costs in connection with such
                                proceeding paid by that Party (on a pro rata
                                basis based on each Party's respective
                                litigation costs, to the extent the recovery was
                                less than all such litigation costs); and

                        b.      Second, the remainder of the recovery shall be
                                paid [**] percent ([**]%) to the Sandoz Parties
                                and [**] ([**]%) to Momenta.

                8.4.5   COOPERATION; SETTLEMENTS. In the event that any Party
                takes action pursuant to this Section 8.4, each other Party
                shall cooperate with the Party so acting to the extent
                reasonably possible, including the joining of suit as required
                by this Agreement or as otherwise desirable. No Party
                participating in such suit shall settle or compromise any claim
                or proceeding relating to another Party's Patent Rights or
                Know-How without obtaining the prior written consent of such
                other Party, such consent not to be unreasonably withheld, it
                being understood that the consent of a Third Party licensor of
                such other Party may also be required

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                in order to settle or compromise any claim or proceeding
                relating to such Party's Patent Rights or Know-How.

        8.5.    CLAIMED INFRINGEMENT. In the event that a Party becomes aware
that the manufacture, use, sale, offer to sell or importation of the Product
infringes, or is likely to or is alleged to infringe, the Patent Rights or
Know-How of any Third Party, such Party shall promptly notify the other Parties
in writing, and, with respect to activities undertaken pursuant to this
Agreement, the Parties shall cooperate and shall mutually agree, through the
JSC, upon an appropriate course of action and shall act in accordance with such
JSC-approved course of action; PROVIDED, HOWEVER, that, to the extent that any
action would involve the enforcement of a Party's Patent Rights or the defense
of an Invalidity Claim with respect to a Party's Patent Rights, the general
concepts of Section 8.4 shall apply to the enforcement of such Party's Patent
Rights or the defense of such Invalidity Claim (i.e., the Owning Party shall
have the initial right, and the Non-Owning Party shall have a step-in right in
the case of claims in the Field in the U.S. Territory, to enforce or defend).
Each Party shall provide to each other Party copies of any notices it receives
from Third Parties regarding any patent nullity actions, any declaratory
judgment actions, or any alleged infringement or misappropriation of Momenta IP,
Sandoz IP or the Patent Rights or Know-How of any Third Party. Such notices
shall be provided promptly, but in no event after more than fifteen (15) days
following receipt thereof.

        8.6.    PATENT INVALIDITY CLAIM. Subject to any contractual obligations
to, or restrictions imposed by, a Party's Third Party licensors, if a Third
Party at any time asserts a claim that any Momenta IP or Sandoz IP (in each
case, other than any Product-Specific Patent Rights relevant to the exercise by
Sandoz of the licenses granted in Section 2.1) is invalid or otherwise
unenforceable (an "INVALIDITY CLAIM"), whether as a defense in an infringement
action brought by a Party pursuant to Section 8.4 or in an action brought
against a Party under Section 8.5, the general concepts of Section 8.4 shall
apply to such Invalidity Claim (i.e., the Owning Party shall have the initial
right, and the Non-Owning Party shall have a step-in right in the case of claims
in the Field in the U.S. Territory, to defend such Invalidity Claim). No Party
shall settle or compromise any Invalidity Claim without obtaining the prior
written consent of Momenta or BCWI (or Sandoz, if so designated in writing by
the Sandoz Parties), such consent not to be unreasonably withheld, it being
understood that the consent of a Third Party licensor of Momenta or BCWI (or
Sandoz, if so designated in writing by the Sandoz Parties), respectively, may
also be required in order to settle or compromise such Invalidity Claim.

        8.7.    JOINT COLLABORATION IP AND PRODUCT-SPECIFIC PATENT RIGHTS.
Subject to any contractual obligations to, or restrictions imposed by, the
Parties' Third Party licensors, the JSC shall make all decisions regarding
enforcement of the Joint Collaboration IP and of those Product-Specific Patent
Rights relevant to the exercise by the Sandoz Parties of the licenses granted in
Section 2.1, in the Field, and responses to any assertions by a Third Party that
the Joint Collaboration IP or those Product-Specific Patent Rights relevant to
the exercise by the Sandoz Parties of the licenses granted in Section 2.1 are
invalid or otherwise unenforceable; PROVIDED, HOWEVER, THAT, in the event of a
dispute within the JSC with respect to such decisions, mutually acceptable
outside patent counsel not regularly employed by any Party or their Affiliates
shall be retained to resolve such dispute. Each Party shall provide to the other
Parties copies of any notices it receives from Third Parties regarding any
patent nullity actions, any

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declaratory judgment actions, any alleged infringement or any alleged
misappropriation of the Joint Collaboration IP or those Product-Specific Patent
Rights relevant to the exercise by the Sandoz Parties of the licenses granted in
Section 2.1. Such notices shall be provided promptly, but in no event after more
than fifteen (15) days following receipt thereof.

        8.8.    OBLIGATIONS TO LICENSORS. Notwithstanding anything to the
contrary in this Article 8, the terms of this Article 8 are subject to and
limited by the provisions of any applicable agreement with Third Party
licensors, including, as applicable, the MIT Agreement. Neither Momenta nor the
Sandoz Parties shall amend any agreement existing as of the Effective Date
(including, without limitation, the MIT Agreement) in a manner that would be
inconsistent with this Agreement, nor enter into any agreement after the
Effective Date that would be inconsistent with this Agreement.

        8.9.    PATENT MARKING. Sandoz shall, and shall cause its Affiliates and
distributors, to (a) mark the Product that is manufactured, offered for sale,
sold or imported under this Agreement with the number of each issued patent
under the Momenta IP, Sandoz IP or Joint Collaboration IP that applies to the
Product and (b) comply with the patent marking statutes in each country in which
the Product is manufactured by or on behalf of Sandoz or its Affiliates.

9.      WARRANTIES

        9.1.    REPRESENTATIONS AND WARRANTIES OF THE PARTIES. Each of Momenta,
on the one hand, and each Sandoz Party, on the other hand, (the "REPRESENTING
PARTY") represents and warrants, or covenants, to the Sandoz Parties and
Momenta, respectively, that:

                9.1.1   The Representing Party is a corporation duly organized,
                validly existing and in good standing under the laws of its
                state of incorporation or foreign jurisdiction;

                9.1.2   The Representing Party has the requisite corporate power
                and authority to execute and deliver this Agreement and to
                perform all of its obligations hereunder. The execution and
                delivery of this Agreement and the performance by the
                Representing Party of its obligations hereunder have been
                authorized by all requisite corporate action on its part. This
                Agreement has been validly executed and delivered by the
                Representing Party, and, assuming that such document has been
                duly authorized, executed and delivered by the other Party,
                constitutes a valid and binding obligation of the Representing
                Party, enforceable against such Party in accordance with its
                terms;

                9.1.3   Except as otherwise set forth in this Agreement, no
                material filing with, and no material permit, authorization,
                consent or approval of any governmental authority is necessary
                for the consummation by the Representing Party of the
                transactions contemplated by this Agreement, except for those
                filings, permits, authorizations, consents or approvals, the
                failure of which to be made or obtained would not materially
                impair such Party's ability to consummate the transactions

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                contemplated hereby or materially delay the consummation of the
                transactions contemplated hereby;

                9.1.4   The execution and delivery of this Agreement by the
                Representing Party and the performance by such Party of its
                obligations hereunder, will not (a) violate the certificate of
                incorporation, by-laws or other organizational document of such
                Party; (b) conflict in any material respect with or result in a
                material violation or breach of, or constitute a material
                default under, any material contract, agreement or instrument to
                which such Party is bound, or result in the creation of
                imposition of any material lien upon the Product; or (c) violate
                or conflict in any material respect with any material law, rule,
                regulation, judgment, order or decree of any court or
                governmental authority applicable to such Party or the Product;

                9.1.5   The Representing Party has the full power and right to
                grant to the relevant Party the license rights set forth in
                Article 2 and Sections 3.4.6, 11.6.1 and 11.6.2, free of any
                liens or encumbrances (other than the rights of any Third Party
                licensors therein);

                9.1.6   The Representing Party has not, as of the Effective
                Date, received any notice from any Third Party that the practice
                of the Momenta IP, if the Representing Party is Momenta, or the
                Sandoz IP, if the Representing Party is Sandoz or BCWI,
                infringes any patent or other proprietary rights of any Third
                Party, and the Representing Party has, as of the Effective Date,
                no knowledge that any Third Party patent or proprietary rights
                are infringed as of the Effective Date by the practice by
                Momenta of the Momenta IP, if the Representing Party is Momenta,
                or by the practice by the Sandoz Parties of the Sandoz IP, if
                the Representing Party is Sandoz or BCWI;

                9.1.7   As of the Effective Date, there are no interferences or
                oppositions pending before any court or administrative office or
                agency relating to the Momenta IP, if the Representing Party is
                Momenta, or the Sandoz IP, if the Representing Party is Sandoz
                or BCWI;

                9.1.8   To the Representing Party's best knowledge, as of the
                Effective Date, all Momenta IP, if the Representing Party is
                Momenta, or Sandoz IP, if the Representing Party is Sandoz or
                BCWI, is valid and enforceable and has not been challenged in
                any judicial or administrative proceeding; and

                9.1.9   There is no action or proceeding pending or, insofar as
                the Representing Party knows as of the Effective Date,
                threatened against the Representing Party before any court,
                administrative agency or other tribunal that might have a
                material adverse effect on the Representing Party's performance
                of this Agreement.

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        9.2.    MOMENTA REPRESENTATIONS. Momenta represents and warrants to
Sandoz that Momenta has delivered to Sandoz, on or before the Effective Date, a
copy of each invention assignment agreement between Momenta and each employee of
Momenta employed as of or prior to the Effective Date, in which such employee
has assigned to Momenta all of such employee's rights in any invention which is
encompassed by the Momenta IP and which is or was conceived, reduced to practice
or developed by such employee during the term of his or her employment with
Momenta.

        9.3.    SANDOZ PARTIES REPRESENTATIONS. Each Sandoz Party represents and
warrants to Momenta that Sandoz and BCWI are Affiliates of each other.

        9.4.    COVENANT. In performing its obligations hereunder, Momenta shall
not, during the Term, use any research tool, patent or know how for the [**]
where the use of such tool, in and of itself, would constitute the willful
infringement or misappropriation of the Patent Rights or trade secret rights of
any Third Party, it being understood that if a Party becomes aware of such an
infringement, or likelihood of or allegation of such an infringement or
misappropriation, of the Patent Rights or trade secret rights of a Third Party,
the provisions of Section 8.5 shall apply to such circumstance.

        9.5.    NO RELIANCE BY THIRD PARTIES. The representations, warranties
and covenants of a Party set forth in this Agreement are intended for the sole
and exclusive benefit of the other Party hereto and the Indemnified Parties, and
may not be relied upon by any Third Party other than the Indemnified Parties,
and may only be relied on by the Indemnified Parties for purposes of their
indemnity hereunder.

        9.6.    NO OTHER WARRANTIES. Nothing in this Agreement shall be
construed as a representation made or warranty given by any Party that (a) any
patents will issue based on pending patent applications, (b) any pending patent
applications or patents issued thereon will be valid, or (c) no Third Party will
bring a claim against Sandoz, BCWI, Momenta or any of their Affiliates or
licensees claiming infringement or misappropriation of such Third Party's Patent
Rights, Know-How or confidential information. EXCEPT AS OTHERWISE EXPRESSLY SET
FORTH IN THIS AGREEMENT, EACH PARTY EXPRESSLY DISCLAIMS, WAIVES, RELEASES AND
RENOUNCES ANY WARRANTY, EXPRESS OR IMPLIED, INCLUDING, WITHOUT LIMITATION, ANY
WARRANTY OF TITLE, NON-INFRINGEMENT, MERCHANTABILITY AND FITNESS FOR A
PARTICULAR PURPOSE.

10.     CONFIDENTIALITY

        10.1.   PRIOR CONFIDENTIALITY AGREEMENT. Momenta and Sandoz are parties
to a certain Confidentiality Agreement dated as of June 17, 2003 (the "PRIOR
CONFIDENTIALITY AGREEMENT"). The provisions of this Article 10 shall apply to
all Confidential Information, and to all Proprietary Information (as that term
is defined in the Prior Confidentiality Agreement) disclosed pursuant to the
Prior Confidentiality Agreement (which shall be deemed to be Confidential
Information, subject to the exceptions in Section 1.18, for purposes of this
Agreement). The nature or terms of this Agreement shall be deemed to be
Confidential Information of each Party, subject to the exceptions in Section
1.18, for purposes of this Agreement.

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        10.2.   CONFIDENTIAL INFORMATION. Each of Sandoz, BCWI and Momenta (the
"RECEIVING PARTY") shall keep strictly confidential any Confidential Information
disclosed by any other Party (the "DISCLOSING PARTY"), using at least the same
degree of care that it uses to protect its own confidential or proprietary
information but in no event less than reasonable care.

        10.3.   NONDISCLOSURE OF CONFIDENTIAL INFORMATION. The Receiving Party
shall use Confidential Information solely for the purposes of this Agreement and
the transactions contemplated hereby and shall not disclose or disseminate any
Confidential Information to any Person at any time, except for disclosure to
those of its Affiliates, directors, officers, employees, consultants,
accountants, attorneys, advisers and agents that have a need to know such
information to permit the Receiving Party to exercise its rights or fulfill its
obligations pursuant to this Agreement, PROVIDED THAT such Persons are bound to
maintain the confidentiality of such Confidential Information to the same extent
as if they were parties hereto.

        10.4.   EXCEPTIONS. The foregoing confidentiality and nondisclosure
obligations are subject to the following exceptions:

                10.4.1  The Receiving Party may disclose the Disclosing Party's
                Confidential Information that is required to be publicly
                disclosed by law or by regulation; PROVIDED, HOWEVER, THAT

                a.      the Receiving Party shall (i) use its best efforts to
                        ensure that it discloses the minimum amount of the
                        Disclosing Party's Confidential Information necessary to
                        comply with law, (ii) where possible, seeks confidential
                        treatment for any such information which is disclosed to
                        a governmental agency or group, and (iii) provides the
                        Disclosing Party with prompt advance notice of such
                        disclosure (which notice shall be given at least two (2)
                        Business Days in advance of such disclosure if possible)
                        and reasonable opportunity to review any such disclosure
                        so that the Disclosing Party has the opportunity if it
                        so desires to seek a protective order or other
                        appropriate remedy;

                b.      Momenta shall give Sandoz, on behalf of the Sandoz
                        Parties, a reasonable opportunity to review all filings
                        by Momenta with the United States Securities and
                        Exchange Commission describing the terms of this
                        Agreement prior to submission of such filings, and shall
                        give due consideration to any reasonable comments by
                        Sandoz, on behalf of the Sandoz Parties, relating to
                        such filing, including without limitation the provisions
                        of this Agreement for which confidential treatment
                        should be sought; and

                c.      the Sandoz Parties or their Affiliates may disclose the
                        terms of this Agreement in any filings with the United
                        States Securities and Exchange Commission (provided that
                        the Sandoz Parties or such Affiliates, as applicable,
                        use Commercially Reasonable Efforts to seek confidential
                        treatment for any financial terms).

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                10.4.2  Notwithstanding anything to the contrary in this
                Agreement, each Party, and its employees, representatives or
                other agents, may disclose to any and all Persons, including,
                without limitation, the U.S. Internal Revenue Service, the
                federal tax treatment and tax structure of the transaction and
                all materials of any kind (including opinions or other tax
                analyses) that are provided to such Party relating to such tax
                treatment and tax structure.

                10.4.3  Pursuant to an agreement to maintain confidentiality,
                any Party may discuss the terms of this Agreement with, or
                provide a copy of this Agreement to, its accountants, its
                attorneys and its current, future or potential investors or
                shareholders.

                10.4.4  Any Party may discuss the general terms of this
                Agreement with, but not provide a copy of this Agreement or a
                redacted copy of this Agreement to, a current, future or
                potential investor or shareholder who does not execute an
                agreement to maintain confidentiality, PROVIDED THAT (i) after a
                preliminary conversation, such Party has used Commercially
                Reasonable Efforts to have such investor or shareholder execute
                an agreement to maintain confidentiality and (ii) any disclosure
                pursuant to this Section 10.4.4 may not include the names of the
                other Parties, the specific financial terms of this Agreement
                (including without limitation the specific percentages of Profit
                Interest and royalties and the details of the payment of the
                Development Costs, Legal Expenses and FTE's), the specific terms
                of the rights granted to the Sandoz Parties under Article III,
                or the specifics of the indemnification provided hereunder (in
                each case, unless and until such information is otherwise
                publicly disclosed).

                10.4.5  Pursuant to an agreement to maintain confidentiality,
                Momenta may provide a copy of this Agreement or relevant
                portions thereof, to MIT and any other Third Party licensor, if
                required pursuant to the relevant license agreement with respect
                to Momenta IP.

                10.4.6  Any other disclosure of the nature or terms of this
                Agreement (including, without limitation, any public
                announcements, press releases or similar publicity with respect
                to this Agreement) by Momenta, on the one hand, or either Sandoz
                Party, on the other hand, must be approved in advance in writing
                by Sandoz or Momenta, respectively, as to form and content of
                such disclosure; PROVIDED, HOWEVER, that the contents of any
                public announcement, press release or similar publicity which
                has been reviewed and approved by the reviewing Party can be
                re-released by either Party in any form without a requirement
                for re-approval. The Parties agree that Momenta and the Sandoz
                Parties (or an Affiliate thereof) shall issue a joint press
                release in a mutually agreeable form on an agreed upon date
                within fourteen (14) days after the mutual execution and
                delivery of this Agreement to all Parties.

        10.5.   IDENTIFICATION. In any disclosure by Sandoz or BCWI permitted
hereunder which refers to Momenta IP or the Joint Collaboration IP, Sandoz or
BCWI, as the case may be, shall

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identify Momenta as the inventor, co-inventor, originator, owner, co-owner
and/or licensee, as appropriate, of such Momenta IP or Joint Collaboration IP.
In any disclosure by Momenta permitted hereunder which refers to Sandoz IP or
Joint Collaboration IP, Momenta shall identify Sandoz or BCWI as the inventor,
co-inventor, originator, owner, co-owner and/or licensee, as appropriate, of
such Sandoz IP or Joint Collaboration IP.

        10.6.   EQUITABLE RELIEF. The Receiving Party agrees that any breach of
this Article 10 may cause the Disclosing Party substantial and irreparable
injury and, therefore, in the event of any such breach, in addition to other
remedies that may be available, the Disclosing Party shall have the right to
specific performance and other injunctive and equitable relief.

        10.7.   SURVIVAL. The confidentiality and nondisclosure obligations of
this Article 10 shall survive the expiration or termination of this Agreement
and remain in effect for a period of ten (10) years following the expiration or
termination of this Agreement.

11.     TERM & TERMINATION

        11.1.   TERM. The term of this Agreement (the "TERM") shall begin on the
Effective Date and continue until the last sale of the Product by Sandoz, its
Affiliates or distributors anywhere in the U.S. Territory, unless earlier
terminated by either Party pursuant to the provisions of this Agreement.

        11.2.   TERMINATION FOR CAUSE.

                11.2.1  Momenta, on the one hand, and Sandoz (on behalf of the
                Sandoz Parties), on the other hand, may terminate this Agreement
                for any breach of a material provision by a Sandoz Party or
                Momenta, respectively, [**] after written notice containing
                details of the breach if the breach remains uncured at the end
                of the notice period.

                11.2.2  Notwithstanding Section 11.2.1, in the event that the
                Sandoz Parties are unable to perform any of their respective
                obligations under this Agreement as a result of any interruption
                of the Supply Chain or manufacturing capability for the Product,
                including as a result of any action taken or threatened by the
                FDA or other Regulatory Authority (each such event a "SUPPLY
                INTERRUPTION"), and such inability to perform hereunder would
                otherwise constitute a breach of a material provision of this
                Agreement, and such breach is not cured within [**] following
                receipt by Sandoz (on behalf of the Sandoz Parties) of written
                notice from Momenta of such breach, such Supply Interruption
                shall not be considered a breach of this Agreement provided that
                Sandoz (on behalf of the Sandoz Parties) provides the JSC with
                written notice and evidence, in form and substance reasonably
                satisfactory to the JSC, that the alleged breach is as a result
                of a Supply Interruption within [**] following receipt by Sandoz
                (on behalf of the Sandoz Parties) from Momenta of notice of such
                alleged breach (a "SUPPLY INTERRUPTION NOTICE"). Such Supply
                Interruption Notice shall extend the [**] cure period set forth
                in Section 11.2.1 in accordance with the following procedure:
                (a)

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                Sandoz (on behalf of the Sandoz Parties) shall furnish to the
                JSC a written plan (the "SUPPLY CONTINUATION PLAN") within [**]
                following the JSC's receipt of the Supply Interruption Notice
                setting forth the actions that the Sandoz Parties shall take to
                cure the Supply Interruption as soon as commercially possible
                following the occurrence of the Supply Interruption; (b) the
                Supply Continuation Plan shall be subject to the review and
                approval of the JSC, which shall not be unreasonably withheld,
                conditioned or delayed; (c) following the JSC's review and
                approval of the Supply Continuation Plan, such plan may be
                amended or modified with the prior consent and approval of the
                JSC, which shall approve any reasonable request by the Sandoz
                Parties for such an amendment or modification; and (d) the
                Sandoz Parties shall not be considered in breach of this
                Agreement under Section 11.2.1 as a result of the Supply
                Interruption if the Supply Continuation Plan is approved by the
                JSC and the Sandoz Parties use Commercially Reasonable Efforts
                to execute the Supply Continuation Plan.

                11.2.3  To the extent permitted under applicable law, Momenta,
                on the one hand, and Sandoz (on behalf of the Sandoz Parties),
                on the other hand, may terminate this Agreement effective
                immediately with written notice if a Sandoz Party or Momenta,
                respectively, shall file for bankruptcy, shall be adjudicated
                bankrupt, shall file a petition under insolvency laws, shall be
                dissolved or shall have a receiver appointed for substantially
                all of its property.

                11.2.4  With respect to a default or breach of this Agreement,
                failure of a Party to provide notice to the defaulting or
                breaching Party provided in this Article 11 shall not constitute
                a waiver of the right to give such notice with respect to any
                subsequent default or breach.

        11.3.   TERMINATION DUE TO LACK OF COMMERCIAL VIABILITY. If (a) there is
a withdrawal from the market of all [**] Products due to material safety
concerns, which withdrawal could significantly impact the commercial viability
of the Product, (b) a new product [**] enters the market and the number of units
of [**] sold during the immediately following [**] period is less than [**]
percent ([**]%) of the number of units sold in the twelve-month period
immediately prior to such entry, (c) at least [**] Products (other than [**])
have been on the market in the U.S. Territory for at least [**] each prior to
the U.S. Launch, (d) at least [**] Third-Party Competitors have received
tentative approval of [**] Products prior to Sandoz's receipt of tentative
approval of the [**] for the Product or (e) the Product fails to generate
Profits equal to or greater than [**] percent ([**]%) of corresponding Net Sales
for any Post-Launch Year during the Post-[**] Period, the [**] Period or the
Aventis [**] Period (each, a "COMMERCIAL VIABILITY TRIGGER"), then, for a period
of thirty (30) days after the occurrence of such Commercial Viability Trigger,
Sandoz (on behalf of the Sandoz Parties) shall have the right to terminate this
Agreement upon thirty (30) days' prior written notice to Momenta. The
termination rights specified in this Section 11.3 shall be termed a "COMMERCIAL
VIABILITY TERMINATION".

        11.4.   SANDOZ MILESTONE TERMINATION. If, for any reason other than as a
result of a breach by Sandoz or BCWI under this Agreement, (a) the drug product
form of the Product is not ready for initiation of Stability Studies on or
before [**] or (b) during the course of the Parties'

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attempt to achieve District Court Legal Clearance, a decision by a District
Court, a United States Court of Appeals, or the United States Supreme Court is
issued, or an applicable law or regulation is enacted or amended, which
materially and substantially diminishes achievement of Final Legal Clearance
based on the legal theories and strategies then being pursued by the Parties to
achieve District Court Legal Clearance (including, without limitation, a
District Court Decision that the marketing of the Product by Sandoz or its
Affiliates [**] Patent Rights) (a "LEGAL STRATEGY DIMINISHMENT") (each of
subsections 11.4(a) and 11.4(b) a "SANDOZ MILESTONE TRIGGER"), then for a period
of [**] after the later of the occurrence of such Sandoz Milestone Trigger or
Sandoz's actual knowledge of such Sandoz Milestone Trigger, Sandoz (on behalf of
the Sandoz Parties) shall have the right to terminate this Agreement upon [**]
prior written notice to Momenta (PROVIDED, HOWEVER, THAT, (i) if there is a
dispute between the Parties as to whether a Legal Strategy Diminishment has
occurred, outside patent counsel not regularly employed by any Party or their
Affiliates who is mutually acceptable to the Parties shall be retained to
resolve such dispute, and (ii) if there is a dispute between the Sandoz Parties,
on the one hand, and Momenta, on the other hand, as to whether a Sandoz
Milestone Trigger has occurred, the Agreement shall not be terminated pursuant
to this Section 11.4 unless and until such dispute is resolved, in accordance
with the terms of this Agreement, in Sandoz's favor). The termination rights
specified in this Section 11.4 shall be termed a "SANDOZ MILESTONE TERMINATION".

        11.5.   EXCESSIVE COST TERMINATION. Sandoz (on behalf of the Sandoz
Parties) shall have the right to terminate this Agreement in the event of
excessive Capped Costs, as follows:

                11.5.1  In the event that, prior to the U.S. Launch, the Capped
                Costs exceed the Cost Cap (the "INITIAL EXCESSIVE COST
                TRIGGER"), Sandoz shall have the option, in its sole discretion,
                to terminate this Agreement (the "INITIAL EXCESSIVE COST
                TERMINATION") effective immediately upon written notice thereof
                to Momenta, which option may be exercised by Sandoz within [**]
                after the Parties have, pursuant to Section 4.1, exchanged the
                written reports and invoices which reflect that the Initial
                Excessive Cost Trigger was achieved in the prior Quarter (the
                "INITIAL EXCESSIVE COST TERMINATION OPTION PERIOD").
                Notwithstanding Section 4.1, in the event of an Initial
                Excessive Cost Termination, the Sandoz Parties shall not be
                responsible for any Capped Costs in excess of the Cost Cap,
                except as provided in Section 11.6.1. If Sandoz does not
                exercise its right to an Initial Excessive Cost Termination, the
                Sandoz Parties shall continue to be responsible for Capped Costs
                in excess of the Cost Cap, subject to the provisions of Section
                11.5.2 and SCHEDULE 4.3.

                11.5.2  If, prior to the U.S. Launch, (a) the Capped Costs
                exceed the Cost Cap by more than the then-current Additional
                Costs Amount and (b) more than twelve (12) months have elapsed
                since the expiration of the immediately preceding Excessive Cost
                Termination Option Period (each, an "ADDITIONAL EXCESSIVE COST
                TRIGGER"), Sandoz shall have the option, in its sole discretion,
                to terminate this Agreement (each, an "ADDITIONAL EXCESSIVE COST
                TERMINATION") effective immediately upon written notice thereof
                to Momenta, which option may be exercised by Sandoz within [**]
                after the later of (i) the exchange by the Parties,

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                pursuant to Section 4.1, of the written reports and invoices
                which reflect that such Additional Excessive Cost Trigger was
                achieved in the prior Quarter (each, an "ADDITIONAL EXCESSIVE
                COST TERMINATION OPTION PERIOD") or (ii) the end of such
                twelve-month period. Notwithstanding Section 4.1, in the event
                of an Additional Excessive Cost Termination, the Sandoz Parties
                shall not be responsible for any Capped Costs in excess of the
                amount that triggered the applicable Additional Excessive Cost
                Trigger, except as provided in Section 11.6.1. If Sandoz does
                not exercise its right to an Additional Excessive Cost
                Termination, (A) the Sandoz Parties shall continue to be
                responsible for Capped Costs in excess of the sum of the Cost
                Cap and the then-current Additional Costs Amount, subject to the
                provisions of this Section 11.5.2 and SCHEDULE 4.3, and (B) the
                Additional Costs Amount shall be increased by [**] Dollars
                (U.S.$[**]).

        11.6.   EFFECTS OF TERMINATION.

                11.6.1  In the event of termination of this Agreement by Sandoz
                (on behalf of the Sandoz Parties) pursuant to Sections 11.3,
                11.4 or 11.5, or by Momenta pursuant to Section 11.2, (a) all
                licenses granted by Momenta to the Sandoz Parties or their
                Affiliates shall terminate; (b) all licenses granted by the
                Sandoz Parties to Momenta under Article 2 shall remain in effect
                on an irrevocable, perpetual, sublicenseable (provided that such
                sublicensees comply with the relevant provisions of this
                Agreement) and exclusive basis and shall be converted to
                licenses to (i) Develop, make, have made, use, sell, offer to
                sell, lease, import and export the Product in the Field anywhere
                in the world (subject to the terms of the Non-U.S. Territory
                Agreement, if such has been executed prior to the date of
                termination of this Agreement) and (ii) make, have made and use
                the Product in the Non-U.S. Territory (subject to the terms of
                the Non-U.S. Territory Agreement, if such has been executed
                prior to the date of termination of this Agreement) but only for
                the purposes of sale of the Product in or into the U.S.
                Territory and any country which is not subject to the terms of
                the Non-U.S. Territory Agreement; (c) the license granted by the
                Sandoz Parties to Momenta pursuant to Section 3.4.6 shall remain
                in effect on an irrevocable and perpetual basis; (d) each of
                Sandoz and BCWI shall cease to use and shall assign to Momenta
                all of its right, title and interest in and to all clinical,
                technical and other relevant reports, records, data, information
                and materials relating to the Product and all regulatory filings
                and Marketing Approvals in the U.S. Territory relating to the
                Product (and the Sandoz Parties shall deliver to Momenta, at
                Momenta's expense (or at Sandoz's expense in the case of
                termination by Momenta under Section 11.2), one (1) copy of each
                physical embodiment of the aforementioned items within thirty
                (30) days after termination); (e) Sandoz and BCWI shall cease to
                use in the Field any technology arising out of the Collaborative
                Program, including, without limitation, any manufacturing
                processes; (f) Sandoz and BCWI shall promptly return to Momenta
                all materials and records in their possession or control
                containing Confidential Information of Momenta; (g) Sandoz and
                BCWI shall transfer and assign to Momenta all trademarks and
                tradenames of the Product that have received Marketing Approval
                in the U.S. Territory, except for any such

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                trademarks or tradenames or a part thereof that use the name
                "Novartis" or "Sandoz" or a derivative thereof or any other
                trademark or tradename or part or derivative thereof that is the
                name or derivative of a name of any other Sandoz Affiliate; (h)
                if so requested by Momenta, the Sandoz Parties shall, at
                Momenta's expense (or at Sandoz's expense in the case of
                termination by Momenta under Section 11.2), take reasonable
                steps to assist Momenta in establishing a contract manufacturing
                relationship with their suppliers (if any) of the Product, it
                being understood that Sandoz and BCWI in no way guarantees the
                ability to transfer any such relationship to Momenta; (i) at
                Momenta's request, Sandoz and BCWI shall sell to Momenta at
                Manufacturing Cost all units of the Product, whether in finished
                product or work-in-process form, in their inventory for sale in
                or into the U.S. Territory; (j) subject to any contractual
                obligations to, or restrictions imposed by, the Sandoz Parties'
                Third Party licensors, the Sandoz Parties shall continue to use
                Commercially Reasonable Efforts to timely prepare, file,
                prosecute and maintain, at their expense, Sandoz Patent Rights
                and Sandoz Collaboration Patent Rights in the Field in the U.S.
                Territory; PROVIDED, HOWEVER, THAT if the Sandoz Parties decline
                to file, prosecute or maintain any such Patent Right or if the
                Sandoz Parties elect to allow any such Patent Right to lapse or
                elects to abandon any such Patent Right before all appeals
                within the respective patent office have been exhausted, then,
                subject to any contractual obligations to, or restrictions
                imposed by, the Sandoz Parties' Third Party licensors, (1)
                Momenta shall have the right, at its own expense and upon
                written notice to the relevant Sandoz Party(ies), to assume
                control of the filing, prosecution and maintenance of such
                Patent Right in the relevant Sandoz Party's name or the name of
                its Third Party licensor, as applicable, in which event, the
                relevant Sandoz Party shall provide assistance to and cooperate
                with Momenta in prosecuting the subject Patent Right, should
                Momenta elect to prosecute and maintain the subject Patent
                Right, and (2) the relevant Sandoz Party shall provide Momenta
                with reasonable notice of its decision to decline to file,
                prosecute or maintain any such Patent Right or its election to
                allow any such Patent Right to lapse or its election to abandon
                any such Patent Right so as to permit Momenta (A) to review the
                patent or application, (B) to decide whether to prosecute or
                maintain the same, and (C) to take appropriate action to
                prosecute or maintain the patent application or patent; (k) the
                provisions of Sections 8.4 and 8.8 shall continue to apply with
                respect to Sandoz Patent Rights (and, notwithstanding anything
                therein, any Product-Specific Patent Rights therein) in the
                Field in the U.S. Territory; and (l) the Sandoz Parties shall be
                responsible for all amounts incurred and owing to Momenta
                pursuant to Article 4 hereof (as modified by SCHEDULE 4.3, as
                applicable) prior to the date of termination but not previously
                paid, which payments shall be made in the time and manner
                provided under Article 4. The post-termination license rights
                granted to Momenta in (b) and (c) of this subsection shall apply
                only as to any Sandoz IP that has actually been used in the
                Collaborative Program prior to the date of termination of this
                Agreement, and shall expressly exclude any other Sandoz IP.

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                11.6.2  In the event of termination of this Agreement by Sandoz
                (on behalf of the Sandoz Parties) pursuant to Section 11.2, (a)
                all licenses granted by the Sandoz Parties to Momenta shall
                terminate; (b) all licenses granted by Momenta to the Sandoz
                Parties under this Agreement shall remain in effect on an
                irrevocable, perpetual, sublicenseable (provided that such
                sublicensees comply with the relevant provisions of this
                Agreement) and exclusive basis; (c) Momenta shall cease to use
                and shall assign to Sandoz all of its right, title and interest
                in and to all clinical, technical and other relevant reports,
                records, data, information and materials relating to the Product
                and all regulatory filings and Marketing Approvals in the U.S.
                Territory relating to the Product (and Momenta shall deliver to
                Sandoz, at Momenta's expense, one (1) copy of each physical
                embodiment of the aforementioned items within thirty (30) days
                after termination); (d) Momenta shall promptly return to Sandoz
                or BCWI, as the case may be, all materials and records in
                Momenta's possession or control containing Confidential
                Information of Sandoz or BCWI, respectively; (e) subject to any
                contractual obligations to, or restrictions imposed by,
                Momenta's Third Party licensors, Momenta shall continue to use
                Commercially Reasonable Efforts to timely prepare, file,
                prosecute and maintain, at its expense, Momenta Patent Rights
                and Momenta Collaboration Patent Rights in the Field in the U.S.
                Territory; PROVIDED, HOWEVER, THAT if Momenta declines to file,
                prosecute or maintain any such Patent Right or if Momenta elects
                to allow any such Patent Right to lapse or elects to abandon any
                such Patent Right before all appeals within the respective
                patent office have been exhausted, then, subject to any
                contractual obligations to, or restrictions imposed by,
                Momenta's Third Party licensors, (1) BCWI (or Sandoz, if so
                designated in writing by the Sandoz Parties) shall have the
                right, at its own expense and upon written notice to Momenta, to
                assume control of the filing, prosecution and maintenance of
                such Patent Right in Momenta's name or the name of its Third
                Party licensor, as applicable, in which event, Momenta shall
                provide assistance to and cooperate with BCWI (or Sandoz, if so
                designated in writing by the Sandoz Parties) in prosecuting the
                subject Patent Right, should BCWI (or Sandoz, if so designated
                in writing by the Sandoz Parties) elect to prosecute and
                maintain the subject Patent Right, and (2) Momenta shall provide
                BCWI (or Sandoz, if so designated in writing by the Sandoz
                Parties) with reasonable notice of its decision to decline to
                file, prosecute or maintain any such Patent Right or its
                election to allow any such Patent Right to lapse or its election
                to abandon any such Patent Right so as to permit BCWI (or
                Sandoz, if so designated in writing by the Sandoz Parties) (A)
                to review the patent or application, (B) to decide whether to
                prosecute or maintain the same, and (C) to take appropriate
                action to prosecute or maintain the patent application or
                patent; (f) the financial obligations set forth in Article 4
                (other than Sections 4.1 and 4.2), including the provisions of
                SCHEDULE 4.3, each as applicable, the patent marking obligations
                set forth in Section 8.9, and the insurance obligations of
                Section 12.4 shall remain in effect; (g) in the event the Sandoz
                Parties' rights under Section 3.4 have not yet lapsed at the
                time of termination, the rights of the Sandoz Parties under
                Section 3.4 shall survive in accordance with the terms thereof;
                (h) subject to the provisions of Article 3, for as

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                long as Sandoz is marketing the Product and abiding by its
                financial obligations to Momenta pursuant to subsection (f) of
                this Section 11.6.2, Momenta shall not provide any Patent
                Rights, Know-How or any other assistance to any third party to
                Characterize, develop, produce, manufacture or Commercialize
                Lovenox(R)-Equivalent Products in the Field in the U.S.
                Territory, or, in the event that the Sandoz Parties' rights
                under Section 3.4 have not yet lapsed at the time of such
                termination, worldwide; and (i) the provisions of Sections 8.4
                and 8.8 shall continue to apply with respect to Momenta Patent
                Rights (and, notwithstanding anything therein, any
                Product-Specific Patent Rights therein) in the Field in the U.S.
                Territory. The post-termination license rights granted to the
                Sandoz Parties in (b) and (c) of this subsection shall apply
                only as to any Momenta IP that has actually been used in the
                Collaborative Program prior to the date of termination of this
                Agreement, and shall expressly exclude any other Momenta IP.

                11.6.3  In the event that, subsequent to any Initial Excessive
                Cost Termination or Additional Excessive Cost Termination,
                Momenta, its Affiliates, licensees or distributors is selling
                the Product in the U.S. Territory, then, in addition to the
                provisions of Section 11.6.1, for each Quarter during which
                Momenta, its Affiliates or licensees is selling the Product in
                the U.S. Territory, Momenta shall pay the Sandoz Parties (in the
                proportion designated by Sandoz) a royalty (the "SANDOZ PARTIES
                ROYALTY") as a percentage of Net Sales by Momenta, its
                Affiliates, licensees or distributors of the Product in the U.S.
                Territory, to be computed according to the following table, by
                multiplying Net Sales by Momenta, its Affiliates or licensees in
                the U.S. Territory for such Quarter times the applicable
                percentage listed in the table:

<Table>
<Caption>
                                                              Royalty Rate
                                                              ------------
                 <S>                                     <C>               <C>
                 NET SALES IN THE U.S.
                 TERRITORY DURING SUCH QUARTER           [**]              [**]

                 For all such Net Sales                  [**]%             [**]%
</Table>

                If, during a particular Quarter, the number of Third-Party
                Competitors changes, the Sandoz Parties Royalty shall be paid
                based on actual Net Sales made during such Quarter under the
                respective royalty rates.

        11.7.   BANKRUPTCY. All rights and licenses granted under or pursuant to
any Section of this Agreement are, and shall otherwise be deemed to be, for
purposes of Section 365(n) of the Bankruptcy Code, licenses of rights to
"intellectual property" as defined under Section 101(35A) of the Bankruptcy
Code. The Parties shall retain and may fully exercise all of their respective
rights and elections under the Bankruptcy Code. Upon the bankruptcy of any
Party, the non-bankrupt Party shall further be entitled to a complete duplicate
of (or complete access to, as appropriate) any such intellectual property, and
such, if not already in its possession, shall be promptly delivered to the
non-bankrupt Party, unless the bankrupt Party elects to continue, and continues,
to perform all of its obligations under this Agreement.

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        11.8.   SURVIVAL. Upon expiration or termination of this Agreement for
any reason, (a) nothing in this Agreement shall be construed to release either
Party from any obligations that were incurred prior to the effective date of
expiration or termination; (b) the following provisions shall expressly survive
any such expiration or termination: Articles 1, 10 and 14, Sections 2.5, Article
3 (to the extent that the Agreement has terminated as a result of a breach by
Momenta under Section 11.2), Sections 4.11, 4.12, 8.1, 8.2.3, 9.6, 11.6 (as
applicable), 11.7, 11.8, 11.9, 13.2, 13.3, and SCHEDULE 4.3 (to the extent
applicable); and (c) (i) the obligations to indemnify under Sections 12.1 and
12.2 (subject to Section 12.3) shall survive the expiration or termination of
this Agreement with respect to any Liabilities, whether asserted during or after
the Term, that result from activities that occurred before or during the Term,
(ii) the obligations of Momenta to indemnify the Sandoz Indemnified Parties
under Section 12.2 (subject to Section 12.3) shall survive the expiration or
termination of this Agreement with respect to any Liabilities that result from
activities that occur after the Term pursuant to Section 11.6.1, (iii) the
obligations of the Sandoz Parties to indemnify the Momenta Indemnified Parties
under Section 12.1 (subject to Section 12.3) shall survive the expiration or
termination of this Agreement with respect to any Liabilities that result from
activities that occur after the Term pursuant to Section 11.6.2, and (iv)
otherwise there shall be no continuing obligation of the Indemnifying Party to
indemnify, defend or hold harmless the Indemnified Party after the date of
expiration or termination of this Agreement.

        11.9.   NON-EXCLUSIVE REMEDY. Termination of this Agreement shall be in
addition to, and shall not prejudice, the Parties' remedies at law or in equity,
including, without limitation, the Parties' ability to receive legal damages
and/or equitable relief with respect to any breach of this Agreement, regardless
of whether or not such breach was the reason for the termination.

12.     INDEMNIFICATION

        12.1.   SANDOZ INDEMNIFICATION OF MOMENTA. The Sandoz Parties shall
indemnify, defend and hold harmless the Momenta Indemnified Parties from and
against all losses, costs, damages, judgments, settlements, interest, fees or
expenses (including all reasonable attorneys' fees, experts' or consultants'
fees, expenses and costs) ("LIABILITIES") awarded to a Third Party against any
Momenta Indemnified Party, or that may be incurred or paid by any Momenta
Indemnified Party in the defense or compromise of legal or equitable claims
asserted by a Third Party, arising out of or resulting from (a) any breach of
any obligation by Sandoz or BCWI hereunder, (b) any misrepresentation by Sandoz
or BCWI hereunder (including but not limited to any such breach by Sandoz or
BCWI of Article 9 - Warranties), (c) any Patent Litigation, (d) any property
damage or personal injury (including, without limitation, death) resulting from
the development, use, manufacture, sale, offering for sale or importation of the
Product by Sandoz, its Affiliates or their Third Party contractors or
distributors, or (e) any claims or demands related to the Product that are
commenced by [**] any Third Party against any Momenta Indemnified Party based on
the activities of Momenta or the Sandoz Parties (including those undertaken by
Affiliates or Third Parties on behalf of Momenta or the Sandoz Parties) [**]
pursuant to this Agreement; PROVIDED, HOWEVER, that the Sandoz Parties shall
have no obligation to indemnify the Momenta Indemnified Parties against
Liabilities under (a) through (e) to the extent that such Liabilities arise from
any Third Party legal or equitable claim that is subject to Momenta's obligation
to indemnify, defend, and hold the Sandoz Indemnified Parties harmless under
Section 12.2.

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        12.2.   MOMENTA INDEMNIFICATION OF SANDOZ. Momenta shall indemnify,
defend and hold harmless the Sandoz Indemnified Parties from and against all
Liabilities awarded to a Third Party against the Sandoz Indemnified Parties or
that may be incurred or paid by any of the Sandoz Indemnified Parties in the
defense or compromise of legal or equitable claims asserted by a Third Party,
arising out of or resulting from (a) any breach of any obligation by Momenta
hereunder, including, without limitation, the covenant in Section 9.4, (b) any
misrepresentation by Momenta hereunder (including but not limited to any such
breach by Momenta of Article 9 - Warranties) of this Agreement, or (c) any
actual misappropriation by any Momenta Indemnified Party of any Third Party
trade secret or know-how, provided that, (i) with respect to actual
misappropriation, there has been a final adjudication of liability for
misappropriation by a court of competent jurisdiction, or, (ii) with respect to
misappropriation that has been alleged but not finally adjudicated, there is a
settlement with a Third Party which the Parties determine by mutual agreement
constitutes an acknowledgement by Momenta of actual misappropriation. (either
case under (i) or (ii) being a "FINAL MISAPPROPRIATION DETERMINATION"). If there
is a dispute between the Parties as to whether a settlement constitutes such an
acknowledgement, nationally-recognized outside counsel not regularly employed by
any Party or their Affiliates who is mutually acceptable to the Parties shall be
retained to resolve such dispute. In the event that Sandoz has, pursuant to the
provisions of Section 12.1, incurred Liabilities with respect to an actual or
alleged misappropriation by any Momenta Indemnified Party of any Third Party
trade secret or know-how and a Final Misappropriation Determination occurs,
Momenta shall, in addition to indemnifying the Sandoz Indemnified Parties for
such Liabilities incurred by them pursuant to subsection (c) of this Section
12.2, reimburse Sandoz for any Liabilities which Sandoz previously paid to or
incurred on behalf of any of the Momenta Indemnified Parties that are allocable
to the misappropriation claim that gave rise to the Final Misappropriation
Determination.

        12.3.   PROCEDURE. If any Momenta Indemnified Party or any Sandoz
Indemnified Party (in each case, an "INDEMNIFIED PARTY") receives any written
claim or demand which such Indemnified Party believes is the subject of
indemnity hereunder by Sandoz or Momenta as the case may be (in each case, an
"INDEMNIFYING PARTY"), the Indemnified Party shall, as soon as reasonably
practicable after forming such belief, give notice thereof to the Indemnifying
Party; PROVIDED THAT the failure to give timely notice to the Indemnifying Party
as contemplated hereby shall not release the Indemnifying Party from any
liability to the Indemnified Party unless the Indemnifying Party demonstrates
that the defense of such claim is materially prejudiced by such failure. The
Indemnifying Party shall assume and diligently pursue the defense of such claim,
at its cost, with counsel reasonably satisfactory to the Indemnified Party. The
Indemnifying Party shall have absolute control of the conduct of the litigation;
PROVIDED, HOWEVER, THAT

                12.3.1  the Indemnified Party may, nevertheless, participate
                therein through counsel of its choice and at its cost, and shall
                be permitted to effectively associate with the Indemnifying
                Party in the defense, the prosecution and the negotiation of any
                settlement of the claim or demand;

                12.3.2  the Indemnifying Party shall keep the Indemnified Party
                informed, through the JSC, of the status of the litigation;

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                12.3.3  the Indemnifying Party shall provide the Indemnified
                Party with a reasonable opportunity to review and comment on all
                pleadings, motions and other papers exchanged with the opposing
                party or filed with any court by the Indemnifying Party with
                respect to such claim or demand (collectively, the "PLEADINGS")
                and the Indemnifying Party shall consider in good faith any
                input provided by the Indemnified Party with respect to the
                Pleadings; and

                12.3.4  if the suit includes a defense of Momenta IP or an
                Invalidity Claim with respect to Momenta IP or the Joint
                Collaboration IP (in the event Momenta is the Indemnified
                Party), then the Indemnifying Party's conduct of the litigation
                with respect to such claim(s) shall be subject to:

                a.      the approval of Momenta and/or

                b.      any contractual obligations to, or restrictions imposed
                        by, the relevant Third Party licensor.

        The Party not assuming the defense of any such claim or demand shall
render all reasonable assistance to the Party assuming such defense as requested
by such defending Party, and all reasonable out-of-pocket costs of such
assistance shall be for the account of the Indemnifying Party. No such claim or
demand shall be settled other than by the Party defending the same, and then
only with the consent of the other Party, which shall not be unreasonably
withheld; PROVIDED THAT the Indemnified Party shall have no obligation to
consent to any settlement of any such claim which imposes on the Indemnified
Party any liability or obligation which cannot be assumed and performed in full
by the Indemnifying Party (subject, in the case of a Settlement, to the terms of
Section 4.3) or which agrees that any element of any of Momenta IP or Joint
Collaboration IP (in the event Momenta is the Indemnified Party) is invalid, not
infringed or unenforceable.

        12.4.   INSURANCE. The Sandoz Parties shall be self-insured. To the
extent Momenta is required to obtain the consent or waiver of MIT under the MIT
Agreement to permit such self-insurance by the Sandoz Parties, Momenta shall use
its best efforts to obtain such waiver or consent. Momenta shall comply with the
insurance obligations imposed on Momenta pursuant to the MIT Agreement.

13.     DISPUTE RESOLUTION

        13.1.   FIRST LEVEL RESOLUTION. Unless otherwise expressly provided for
herein, any claim or controversy between Momenta, on the one hand, and the
Sandoz Parties, on the other hand, arising out of or relating to the execution,
interpretation and performance of this Agreement (including the validity, scope
and enforceability of this provision) which has not been resolved by the JPT
will be identified in writing and presented by the JPT to the JSC. The JSC shall
meet within fourteen (14) days after delivery of the notice of dispute pursuant
to this Section 13.1 and attempt in good faith to resolve the dispute. If the
JSC is unable to decide or resolve an issue unanimously or in the event of any
dispute or claim arising out of or relating to this Agreement, or to the breach,
termination, or validity of this Agreement a notice of dispute shall be
submitted

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to the relevant Executive Officers of the Parties for resolution by good-faith
negotiations pursuant to Section 13.2.

        13.2.   NEGOTIATION BETWEEN EXECUTIVES. Within fourteen (14) days after
delivery of the notice of dispute pursuant to Section 13.1, the Sandoz Executive
Officer (unless the Sandoz Parties designate, within one (1) Business Day after
delivery of the notice of dispute pursuant to Section 13.1, that the BCWI
Executive Officer shall participate instead) and the Momenta Executive Officer
shall meet at a mutually acceptable time and place, and thereafter as often as
they reasonably deem necessary, to attempt to resolve the dispute in good faith.
All reasonable requests for information made by one Party to another will be
honored. All negotiations pursuant to this clause are confidential and shall be
treated as compromise and settlement negotiations for purposes of applicable
rules of evidence. If such Executive Officers cannot resolve such dispute within
fourteen (14) days after such meeting, then each Party reserves its right to any
and all remedies available under law or equity with respect to any other
dispute. Notwithstanding the foregoing, such Executive Officers shall meet and
attempt to resolve any dispute regarding the strategy to achieve Legal Clearance
within seven (7) days (or such other mutually agreed period) after delivery of
the notice of dispute pursuant to Section 13.1, and, if such Executive Officers
cannot resolve such dispute within such time period, then (except as provided in
Section 11.4) such dispute shall be considered resolved in Sandoz's favor.

        13.3.   LEGAL REMEDIES. Notwithstanding anything to the contrary in this
Article 13, any Party may seek immediate injunctive or other interim relief from
any court of competent jurisdiction as necessary to enforce and prevent
infringement or misappropriation of the patent rights, copyright rights,
trademarks, confidential information, trade secrets, or other intellectual
property rights owned or controlled by a Party or its Affiliates or to prevent
breach of Article 10.

14.     ADDITIONAL PROVISIONS

        14.1.   ENTIRE AGREEMENT. This Agreement, including the Schedules
hereto, contains the entire agreement and understanding between the Parties
relating to the subject matter hereof and all prior agreements and
understandings between the Parties and relating to the subject matter hereof,
including, without limitation, the Prior Confidentiality Agreement, are
superseded by this Agreement. Neither Party shall be liable or bound to any
other Party in any manner by any representations, warranties or covenants
relating to such subject matter except as specifically set forth herein.

        14.2.   AMENDMENTS AND WAIVER. This Agreement may not be amended except
by an instrument in writing signed on behalf of each of the Parties. By an
instrument in writing either Party may waive compliance by the other Party with
any term or provision of this Agreement that such other Party was or is
obligated to comply with or perform. Any failure of a Party to enforce at any
time, or for any period of time, any of the provisions of this Agreement shall
not be deemed or construed to be a waiver of such provisions or a waiver of any
right of such Party thereafter to enforce each and every such provision on any
succeeding occasion or breach thereof.

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        14.3.   ASSIGNMENT. This Agreement shall be assignable only: (a) by a
Party to an Affiliate of that Party, without the consent of the other Parties,
PROVIDED THAT in such case, the assigning Party remains liable with the assignee
for all of its obligations hereunder; (b) by a Party with the written consent of
the other Parties; or (c) automatically by a Party without the consent of the
other Parties to (i) the purchaser of (A) all or substantially all of the
assets, or (B) a majority of the voting equity securities, of the assigning
Party's business to which this Agreement relates, or (ii) the surviving Person,
in the event of a merger of the assigning Party and another Person, and any such
purchaser or successor shall be bound by the terms hereof. Any attempted
assignment that does not comply with the terms of this Section 14.3 shall be
void. This Agreement shall be binding upon and inure to the benefit of the
Parties, their successors and permitted assigns.

        14.4.   NATURE OF RELATIONSHIP. In making and performing this Agreement,
the Parties are acting, and intend to be treated, as independent entities and
nothing contained herein shall be deemed or implied to create an agency,
distributorship, joint venture or partnership relationship among the Parties
hereto. Except as otherwise expressly provided herein, no Party may make any
representation, warranty or commitment, whether express or implied, on behalf of
or incur any charges or expenses for, or in the name of, any other Party. Except
as provided in Article 12 or Section 4.11.8, no Party shall be liable for the
act of any other Party unless such act is expressly authorized in writing by the
Parties hereto.

        14.5.   NOTICES. All notices and other communications required or
permitted to be given or made pursuant to this Agreement shall be in writing
signed by the sender and shall be deemed duly given (a) on the date delivered,
if personally delivered, (b) on the date sent by telecopier with automatic
confirmation by the transmitting machine showing the proper number of pages were
transmitted without error, (c) on the Business Day after being sent by Federal
Express or another recognized overnight mail service which utilizes a written
form of receipt for next day or next business day delivery, or (d) two (2)
Business Days after mailing, if mailed by United States postage-prepaid
certified or registered mail, return receipt requested, in each case addressed
to the applicable party at the address set forth below; PROVIDED THAT a Party
may change its address for receiving notice by the proper giving of notice
hereunder:

        IF TO SANDOZ:                           IF TO MOMENTA:

        Geneva Pharmaceuticals, Inc.            Momenta Pharmaceuticals, Inc.
        506 Carnegie Center, Suite 400          43 Moulton Street
        Princeton, NJ 08540                     Cambridge, MA 02138
        Attn: Chief Executive Officer           Attn: Chief Executive Officer
        Tele: (609) 627-8500                    Tele: 617-491-9700
        Fax:  (609) 627-8684                    Fax:  617-491-9701

        WITH A COPY TO:                         WITH A COPY TO:

        Geneva Pharmaceuticals, Inc.            Hale and Dorr LLP
        506 Carnegie Center, Suite 400          60 State Street

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        Princeton, NJ 08540                     Boston, MA 02109
        Attn: Chief Executive Officer           Attn: Steven D. Singer, Esq.
        Tele: (609) 627-8500                    Tele: (617) 526-6000
        Fax:  (609) 627-8684                    Fax:  (617) 526-5000

        IF TO BCWI:                             IF TO SANDOZ GMBH:

        Biochemie West Indies N.V.              Sandoz GmbH
        Pietermaai 6A                           Biochemiestrasse 10
        Willemstad, Curacao                     Kundl, Austria
        Netherlands Antilles                    Attn: Legal Counsel
        Attn: Guido Schwaiger, Head Caribic     Tele: 01143 5338 200 2207
        Tele: 599-9-461-4084                    Fax:  01143 5338 8828
        Fax: 599-9-461-1460

        WITH A COPY TO:
        Sandoz GmbH
        Biochemiestrasse 10
        Kundl, Austria
        Attn: Legal Counsel
        Tele: 01143 5338 200 2207
        Fax:  01143 5338 8828

        14.6.   GOVERNING LAW. This Agreement and any and all matters arising
directly or indirectly herefrom shall be governed by and construed and enforced
in accordance with the internal laws of the State of New York applicable to
agreements made and to be performed entirely in such state, without giving
effect to the conflict of law principles thereof.

        14.7.   JURY WAIVER. EACH PARTY HERETO HEREBY WAIVES, TO THE FULLEST
EXTENT PERMITTED BY APPLICABLE LAW, ANY RIGHT IT MAY HAVE TO A TRIAL BY JURY IN
RESPECT OF ANY CLAIM BASED UPON, DIRECTLY OR INDIRECTLY ARISING OUT OF, UNDER OR
IN CONNECTION WITH THIS AGREEMENT AND THE TRANSACTIONS CONTEMPLATED HEREBY. EACH
PARTY HERETO ACKNOWLEDGES THAT IT AND THE OTHER PARTY HERETO HAVE BEEN INDUCED
TO ENTER INTO THIS AGREEMENT BY, AMONG OTHER THINGS, THE MUTUAL WAIVERS AND
CERTIFICATIONS IN THIS SECTION 14.7.

        14.8.   COUNTERPARTS; FACSIMILE SIGNATURE. This Agreement may be
executed in any number of counterparts, each of which shall be an original, but
all of which together shall constitute one instrument. This Agreement may also
be executed via facsimile, which shall be deemed an original.

        14.9.   SEVERABILITY. In the event that any one or more of the
provisions contained herein, or the application thereof in any circumstances, is
held invalid, illegal or unenforceable in any respect for any reason, the
Parties shall negotiate in good faith with a view to the substitution therefor
of a suitable and equitable solution in order to carry out, so far as may be
valid and

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enforceable, the intent and purpose of such invalid provision; PROVIDED,
HOWEVER, THAT the validity, legality and enforceability of any such provision in
every other respect and of the remaining provisions contained herein shall not
be in any way impaired thereby, it being intended that all of the rights and
privileges of the Parties hereto shall be enforceable to the fullest extent
permitted by law.

        14.10.  EXPENSES. Each Party hereto shall bear its own direct and
indirect expenses incurred in connection with the negotiation and preparation of
this Agreement and, except as set forth in this Agreement, the performance of
the obligations contemplated hereby and thereby.

        14.11.  FURTHER ACTIONS AND DOCUMENTS. Each Party agrees to execute,
acknowledge and deliver all such further instruments, and to do all such further
acts, as may be reasonably necessary or appropriate to carry out the intent and
purposes of this Agreement.

        14.12.  USE OF TRADE NAMES AND TRADEMARKS. Each Party recognizes that
the name of the other Party represents valuable assets of such other Party and
that substantial recognition and goodwill are associated with such assets. Each
Party hereby agrees that neither it nor any of its Affiliates shall use such
assets of the other Party without prior written authorization from such other
Party. Nothing in this Agreement constitutes a license entitling any Party to
use any other Party's name, logos or trademarks; provided, however, that any
Party may use any other Party's name, logos or trademarks to the extent
permitted in Section 10.4.

        14.13.  AFFILIATES. To the extent that the rights granted to a Party
hereunder may be and are exercised by an Affiliate of such Party, such Affiliate
shall be bound by the corresponding obligations of such Party.

        14.14.  EXPORTS. The Parties acknowledge that the export of technical
data, materials or products is subject to the exporting Party receiving any
necessary export licenses and that the Parties cannot be responsible for any
delays attributable to export controls that are beyond the reasonable control of
either Party. The Parties agree not to export or re-export, directly or
indirectly, any information, technical data, the direct product of such data,
samples or equipment received or generated under this Agreement in violation of
any governmental regulations that may be applicable. The Parties agree to obtain
similar covenants from their licensees with respect to the subject matter of
this Section 14.14.

        14.15.  FORCE MAJEURE. No failure or omission by a Party hereto in the
performance of any obligation of this Agreement (excluding payment obligations)
shall be deemed a breach of this Agreement or create any liability if the same
shall arise from any cause or causes beyond the reasonable control of such
Party, including, but not limited to, the following: acts of God; acts or
omissions of any government; any rules, regulations or orders issued by any
governmental authority or by any officer, department, agency or instrumentality
thereof; fire; storm; flood; earthquake; accident; war; rebellion; terrorism;
insurrection; riot; and invasion (a "FORCE MAJEURE EVENT"); and PROVIDED THAT
such failure or omission resulting from a Force Majeure Event is cured as soon
as is practicable after the occurrence of such Force Majeure Event. The Party
claiming force majeure shall notify the other Party with notice of the Force
Majeure Event as soon as practicable, but in no event later than fourteen (14)
days after its occurrence, which

                                      -61-
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                                                                  EXECUTION COPY

notice shall reasonably identify such obligations under this Agreement and the
extent to which performance thereof will be affected. In such event, the Parties
shall meet promptly to determine an equitable solution to the effects of any
such Force Majeure Event.

        14.16.  NON-USE OF MIT NAME. Neither Sandoz nor its Affiliates shall use
the name of "MIT," "Lincoln Laboratory" or any variation, adaptation, or
abbreviation thereof, or of any of its trustees, officers, faculty, students,
employees, or agents (collectively, "MIT ASSOCIATES"), or any trademark owned by
MIT, or any terms of the MIT Agreement, in any promotional material or other
public announcement or disclosure without the prior written consent of MIT, or
in the case of the name of any MIT Associate, the written consent of such MIT
Associate. The immediately preceding sentence notwithstanding, without the
consent of MIT (but subject to the provisions of Article 10), Sandoz and its
Affiliates may state that they are sublicensed by MIT under one or more of the
applicable Momenta Patent Rights, may make statements of facts, and may make
disclosures or statements required by law.

        14.17.  HEADINGS. The captions or headings of the Sections or other
subdivisions hereof are inserted only as a matter of convenience or for
reference and are not part of the agreement of the parties and shall have no
effect on the meaning of the provisions hereof. All references in this Agreement
to Sections and Schedules are to sections and schedules to this Agreement,
unless otherwise indicated.

        14.18.  KEY PERSON LIFE INSURANCE. Sandoz may, at its option and sole
expense, secure life insurance policies, naming Sandoz as the beneficiary, with
respect to any principal scientist of Momenta. Momenta shall, at Sandoz's
expense, reasonably cooperate with Sandoz's attempts to secure such life
insurance policies.

        14.19.  NO CONSEQUENTIAL DAMAGES. UNLESS RESULTING FROM A PARTY'S
WILLFUL MISCONDUCT OR FROM A PARTY'S BREACH OF ARTICLE 10, NO PARTY HERETO WILL
BE LIABLE TO ANY OTHER PARTY OR ITS AFFILIATES FOR SPECIAL, INCIDENTAL,
CONSEQUENTIAL, EXEMPLARY, PUNITIVE, MULTIPLE OR OTHER INDIRECT DAMAGES ARISING
OUT OF THIS AGREEMENT OR THE EXERCISE OF ITS RIGHTS HEREUNDER, OR FOR LOSS OF
PROFITS, LOSS OF DATA OR LOSS OF USE DAMAGES ARISING FROM OR RELATING TO ANY
BREACH OF THIS AGREEMENT WHETHER BASED UPON WARRANTY, CONTRACT, TORT, STRICT
LIABILITY OR OTHERWISE, REGARDLESS OF ANY NOTICE OF SUCH DAMAGES. NOTHING IN
THIS SECTION 14.19 IS INTENDED TO LIMIT OR RESTRICT THE INDEMNIFICATION RIGHTS
OR OBLIGATIONS OF ANY PARTY UNDER THIS AGREEMENT.

                  [REMAINDER OF PAGE INTENTIONALLY LEFT BLANK]

                                      -62-
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                                                                  EXECUTION COPY

IN WITNESS WHEREOF, the Parties have executed this Collaboration and License
Agreement in counterparts, effective as of the 1st day of November, 2003.

MOMENTA PHARMACEUTICALS, INC.               GENEVA PHARMACEUTICALS, INC.

By:        /s/ Alan Crane                   By:          [illegible]
       --------------------------                 ------------------------------
Name    Alan Crane                          Name:
       --------------------------                 ------------------------------
Title:  Chief Executive Officer             Title:   Vice President, Bus. Dev.
       --------------------------                 ------------------------------

BIOCHEMIE WEST INDIES, N.V.
By: NOVARTIS INTERNATIONAL A.G., its Managing Director

By:            [illegible]
       --------------------------
Name:
       --------------------------
Title:
       --------------------------

By: SANDOZ GMBH, its Managaing Director

By:        [illegible]                                     [illegible]
       --------------------------                 ------------------------------
Name:
       --------------------------                 ------------------------------
Title:     CFO                                           General Counsel
       --------------------------                 ------------------------------

Sandoz GmbH, a corporation organized under the laws of Austria, hereby
guarantees the performance of the obligations of its subsidiary, Biochemie West
Indies, N.V., under Sections 4.1, 4.2 and 4.3 of the Agreement.

SANDOZ GMBH

By:        [illegible]                                     [illegible]
       --------------------------                 ------------------------------
Name:
       --------------------------                 ------------------------------
Title:     CFO                                           General Counsel
       --------------------------                 ------------------------------

                                      -63-
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                                                                  EXECUTION COPY

                                  SCHEDULE 1.22
                               PRE-EXISTING COSTS

<Table>
<Caption>
     Entity to Be Paid                                    Payment Amount
     -----------------                                    --------------
<S>                                                     <C>
[**]                                                    U.S.$[**]
[**]                                                             [**]
[**]                                                             [**]
[**]                                                             [**]
[**]                                                             [**]
[**]                                                       Up to [**]
[**]                                                             [**]
APPROXIMATE TOTAL:                                      U.S.$[**]
</Table>

NOTE: The above payments exclude the following costs: $[**] to [**] (incurred
through August 2003) and $[**] to [**] (incurred through August 2003), which are
being or were paid solely by Momenta.

*Costs paid as of September 22, 2003. All other costs have been invoiced or
committed. After the Effective Date, further payments will be due under the
agreements with [**]and [**] and the anticipated agreement with [**]. With
respect to [**], a portion of the up to $[**] will be for services conducted
prior to the Effective Date and a portion of the up to $[**] will be for
services conducted on or after the Effective Date. Invoices from [**] for a
total of $[**] have been received to date for the month of September 2003.

**This is only the amount due on 11/01/03.

***Exact amount will be determined from invoices.

****This is only the amount due for initial equipment purchase.

                                      -64-
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                                  SCHEDULE 1.48
                       CALCULATION OF MANUFACTURING COSTS

Manufacturing Cost with respect to a Party's or its Affiliates' cost to
manufacture and/or Label the Product in finished form shall be calculated as the
sum of [Actual Cost of Raw Materials] + [Actual Direct Labor Costs] +
[Manufacturing Overhead Costs], where:

ACTUAL COST OF RAW MATERIALS. The Actual Cost of Raw Materials means: (a) the
actual purchase unit cost of raw materials, including, without limitation, all
starting materials, biological products, biological molecules, chemicals,
precursors, intermediates, reagents, and active pharmaceutical ingredients; and
(b) the actual purchase unit cost of packaging components necessary to
manufacture or Label the Product, as the case may be; in each case of (a) and
(b), multiplied by the actual quantity consumed in the production and
manufacturing and/or Labeling process, as the case may be, including any usage
or yield variances and any write-offs caused by expiration, obsolescence,
accident and/or book-to-physical differences, and (c) all direct shipping costs
to the manufacturer associated with (a) and (b) above.

ACTUAL DIRECT LABOR COSTS. Actual Direct Labor Costs means the actual cost of
direct labor (salary and benefits) to manufacture and/or Label the Product,
including, without limitation, (a) any efficiency, activity and spending
variances from standards; (b) material adjustments for off-grade or defective
material, handling losses, physical adjustments, and salvage; and (c) shipment
charges, including all direct costs of shipping from the Party's manufacturing
and/or distribution facility to a Third Party Labeler and from such Third Party
Labeler to such Party's destination facility.

MANUFACTURING OVERHEAD COSTS. Manufacturing Overhead Costs means the reasonable
manufacturing overhead resources consumed in the manufacturing and production
and/or Labeling process, as the case may be, of a specified quantity of the
Product, which, with respect to any plant, except a plant, or a part of a plant,
built exclusively for the manufacture of the Product, shall be based on the
then-current Full Capacity of the relevant plant, rather than the actual level
of demand throughput, and which shall include, without limitation: (a) normal
depreciation of building, machinery, and equipment; and (b) plant management.
"FULL CAPACITY" means, (x) with respect to a plant operating at or below [**]%
of its Entire Capacity, [**]% of the Entire Capacity, and (y) with respect to a
plant operating above [**]% of its Entire Capacity, the actual demand throughput
at which the plant is operating. "ENTIRE CAPACITY" means production at [**]
percent ([**]%), which shall not exclude any loss of capacity resulting from
planned maintenance.

For the sake of clarity, and by way of examples, (1) if a plant is operating at
[**]% of its Entire Capacity, and [**]% percent of the plant's Entire Capacity
is devoted to the manufacture of the Product, [**]% ([**]) of the plant's
overhead shall be allocated to the Product, and (2) if a plant is operating at
[**]% of its Entire Capacity and [**]% of the plant's Entire Capacity is devoted
to the manufacture of the Product, [**]% ([**]) of the plant's overhead shall be
allocated to the Product.

                                      -65-
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                                  SCHEDULE 1.58
                          CURRENT MOMENTA PATENT RIGHTS

PATENT RIGHTS [**] (LICENSED TO MOMENTA BY MIT IN ACCORDANCE WITH THE MIT
AGREEMENT):

I.       UNITED STATES PATENTS AND APPLICATIONS

                  M.I.T. CASE NO. [**]
                  Entitled: [**]
                           USA Serial No. [**]
                           Entitled: [**]

                  M.I.T. CASE NO. [**]
                  Entitled: [**]
                           USA Serial No. [**]
                           Entitled: [**]

                  M.I.T. CASE NO. [**]
                  Entitled: [**]
                           USA Patent No. [**]
                           Entitled: [**]

                           USA Serial No. [**]
                           Entitled: [**]

                  M.I.T. CASE NO. [**]
                  Entitled: [**]
                           USA Serial No. [**]
                           Entitled: [**]

                  M.I.T. CASE NO. [**](IN PART AS NOTED BELOW)
                  Entitled: [**]

                           USA Serial No. [**]
                           Entitled: [**]

II.      INTERNATIONAL (NON-U.S.) PATENTS AND APPLICATIONS

                  M.I.T. CASE NO. [**]
                  Entitled: [**]
                           EPC Application No. [**]
                           Entitled: [**]
                           Canada Application No.  [**]
                           Entitled: [**]
                           Japanese Application No. [**]
                           Entitled: [**]

                                      -66-
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                                                                  EXECUTION COPY

                  M.I.T. CASE NO. [**]
                  Entitled: [**]
                           EPC Application No. [**]
                           Entitled: [**]
                           Canada Application No. [**]
                           Entitled: [**]
                           Japanese Application No. [**]
                           Entitled: [**]

                  M.I.T. CASE NO. [**]
                  Entitled: [**]
                           PCT Application No. [**]
                           Entitled: [**]

                  M.I.T. CASE NO. [**] (IN PART AS NOTED BELOW)
                  Entitled: [**]
                           WO Application Serial No. [**]
                           Entitled: [**]

PATENT RIGHTS [**](LICENSED TO MOMENTA BY MIT IN ACCORDANCE WITH THE MIT
AGREEMENT):

I.       UNITED STATES PATENTS AND APPLICATIONS

                  M.I.T. CASE NO. [**]
                  Entitled:  [**]

                           USA Patent No. [**]
                           Entitled: [**]

                           USA Patent No. [**]
                           Entitled: [**]

                  M.I.T. CASE NO. [**]
                  Entitled: [**]

                           USA Patent No. [**]
                           Entitled: [**]

                           USA Patent No. [**]
                           Entitled: [**]

                                      -67-
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                                                                  EXECUTION COPY

II.      INTERNATIONAL (NON-U.S.) PATENTS AND APPLICATIONS

                  M.I.T. CASE NO. [**]
                  Entitled: [**]

                           AT Patent No. [**]
                           BE Patent No. [**]
                           CH Patent No. [**]
                           DE Patent No. [**]
                           DK Patent No. [**]
                           ES Patent No. [**]
                           FR Patent No. [**]
                           GB Patent No. [**]
                           GR Patent No. [**]
                           IE Patent No. [**]
                           IT Patent No. [**]
                           LI Patent No. [**]
                           LU Patent No. [**]
                           MC Patent No. [**]
                           NL Patent No. [**]
                           SE Patent No. [**]
                           EP Patent No. [**]
                           All Entitled: [**]

                           CA Patent Application Serial No. [**]
                           Entitled: [**]

                           JP Patent Application Serial No. [**]
                           Entitled: [**]

                                      -68-
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                                                                  EXECUTION COPY

                  M.I.T. CASE NO. 5981
                           Entitled [**]

                           EP Patent No. [**]
                           Entitled: [**]

                           CA Patent No. [**]
                           Entitled: [**]

                           JP Patent Application Serial No. [**]
                           Entitled: [**]

PATENT RIGHTS [**] (LICENSED TO MOMENTA BY MIT IN ACCORDANCE WITH THE MIT
AGREEMENT):

I.       UNITED STATES PATENTS AND APPLICATIONS

                  M.I.T. CASE NO. [**]
                  Entitled: [**]

                           USA Patent No. [**]
                           Entitled: [**]

PATENT RIGHTS [**] (LICENSED TO MOMENTA BY MIT IN ACCORDANCE WITH THE MIT
AGREEMENT):

I.       UNITED STATES PATENTS AND APPLICATIONS

                  M.I.T. CASE NO. [**]
                  Entitled: [**]

                           USA Serial No. [**]
                           Entitled: [**]

                  M.I.T. CASE NO. [**]
                  Entitled: "[**]

                           USA Serial No. [**]
                           Entitled: [**]

                  M.I.T. CASE NO. [**]
                  Entitled: [**]

II.      INTERNATIONAL (NON-U.S.) PATENTS AND APPLICATIONS

                  M.I.T. CASE NO. [**]
                  Entitled: [**]

                           PCT Application No. [**]

                                      -69-
<Page>

                                                                  EXECUTION COPY

                           Entitled: [**]

                  M.I.T. CASE NO. [**]
                  Entitled: [**]

                           JP Patent Application Serial No. [**]
                           Entitled: [**]

MOMENTA-OWNED PATENT RIGHTS:

                  Entitled: [**]
                           US Application No. [**]

                                      -70-
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                                  SCHEDULE 4.3
                               ADJUSTMENT SCHEDULE

A.      OVERVIEW

        The Parties agree that the Sandoz Parties shall have the right to offset
Excess Costs against Commercial Milestone Payments, Profit Interest and
royalties (whether paid pursuant to Sections 4.6.1, 4.7.1 or 4.8.1), to the
extent, and subject to the limitations, set forth in this Schedule.

DEFINITIONS:

        "ACTUAL MOMENTA ECONOMIC INTEREST". Actual Momenta Economic Interest
means, with respect to a Post-Launch Quarter, the percentage calculated in
accordance with the following table:

<Table>
<Caption>
              Quarter                     Actual Momenta Economic Interest
              -------                     --------------------------------
<S>                                    <C>
Each of the First Post-Launch          The percentage calculated by dividing:
Quarter through the [**] Post-Launch
Quarter                                (i)  the sum of the [**] pursuant to this
                                            SCHEDULE 4.3) during such
                                            Post-Launch Quarter and all
                                            preceding Post-Launch Quarters; by

                                       (ii) the [**] for such Post-Launch
                                            Quarter and all preceding
                                            Post-Launch Quarters

The [**] Post-Launch Quarter or any    The percentage calculated by dividing:
subsequent Post-Launch Quarter
                                       (i)  the sum of the [**] pursuant to this
                                            SCHEDULE 4.3) for the [**]
                                            Post-Launch Quarter and any
                                            subsequent Post-Launch Quarters
                                            through the relevant Post-Launch
                                            Quarter; by

                                       (ii) the [**] for the [**] Post-Launch
                                            Quarter and any subsequent
                                            Post-Launch Quarters through the
                                            relevant Post-Launch Quarter
</Table>

        "CARRYFORWARD". Carryforward means that portion of Momenta Share of
Excess Costs and True-Up Amounts that are not deductible from the Profit
Interest or royalties (whether paid pursuant to Sections 4.6.1, 4.7.1 or 4.8.1),
due to the provisions of subsection D of this SCHEDULE 4.3, as shall be adjusted
from time to time pursuant to subsections B.2 and C.3 of this SCHEDULE 4.3.

                                      -71-
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                                                                  EXECUTION COPY

        "ECONOMIC INTEREST VARIANCE". Economic Interest Variance means (a) with
respect to the [**] Post-Launch Year, the difference between the Momenta
Economic Interest for the Fourth Post-Launch Quarter and the Momenta Economic
Interest for the First Post-Launch Quarter, and (b) with respect to the [**]
through [**] Post-Launch Years, the difference between the Momenta Economic
Interest for the last Post-Launch Quarter of such Post-Launch Year and the
Momenta Economic Interest for the last Post-Launch Quarter of the previous
Post-Launch Year.

        "MOMENTA ECONOMIC INTEREST". Momenta Economic Interest means, with
respect to a Post-Launch Quarter, the percentage calculated in accordance with
the following table:

<Table>
<Caption>
                        Quarter                                             Momenta Economic Interest
                        -------                                             --------------------------
<S>                                                          <C>
The [**] Post-Launch Quarter through the [**] Post-Launch    The lesser of (a) the then-current Estimated Momenta
Quarter, inclusve                                            Economic Interest of [**]% or (b) the Actual Momenta
                                                             Economic Interest for the [**] Post-Launch Quarter

The [**] Post-Launch Quarter through the [**] Post-Launch    The lesser of (a) the then-current Estimated Momenta
Quarter, inclusive                                           Economic Interest of [**]% or (b) the Actual Momenta
                                                             Economic Interest for the [**] Post-Launch Quarter

The [**] Post-Launch Quarter through the [**] Post-Launch    The lesser of (a) the then-current Estimated Momenta
Quarter, inclusive                                           Economic Interest of [**]% or (b) the Actual Momenta
                                                             Economic Interest for the [**] Post-Launch Quarter

The [**] Post-Launch Quarter through the [**] Post-Launch    The lesser of (a) the then-current Estimated Momenta
Quarter, inclusive                                           Economic Interest of [**]% or (b) the Actual Momenta
                                                             Economic Interest for the [**] Post-Launch Quarter

The [**] Post-Launch Quarter through the [**] Post-Launch    The lesser of (a) the then-current Estimated Momenta
Quarter, inclusive                                           Economic Interest of [**]% or (b) the Actual Momenta
                                                             Economic Interest for the [**] Post-Launch Quarter

The [**] Post-Launch Quarter                                 The lesser of (a) the then-current Estimated Momenta
                                                             Economic Interest of [**]% or (b) the Actual Momenta
                                                             Economic Interest for the [**]Post-Launch Quarter

The [**] through the [**] Post-Launch Quarter, inclusive     The Actual Momenta Economic Interest for the [**]
                                                             Post-Launch Quarter

The [**] Post-Launch Quarter in the [**]and every            The Actual Momenta Economic Interest for the [**]
subsequent Post-Launch Years                                 Post-Launch Quarter in such Post-Launch Year

Each of the [**] Post-Launch Quarters in the [**] and        The Actual Momenta Economic Interest for the [**]
every subsequent Post-Launch Years                           Post-Launch Quarter in the prior Post-Launch Year
</Table>

        "MOMENTA SHARE OF EXCESS COSTS". Momenta Share of Excess Costs means,
with respect to a Post-Launch Quarter, the product of the New Excess Costs for
such Post-Launch Quarter

                                      -72-
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                                                                  EXECUTION COPY

multiplied by the Momenta Economic Interest for such Post-Launch Quarter, as
shall be adjusted from time to time pursuant to subsections B.2 and C.2 of this
SCHEDULE 4.3.

        "NEW EXCESS COSTS". New Excess Costs means (a) with respect to the [**]
Post-Launch Quarter, the sum of any Excess Costs which were incurred during the
[**] Post-Launch Quarter and all Excess Costs which were incurred prior to the
[**] Post-Launch Quarter, and (b) with respect to any subsequent Post-Launch
Quarter, any Excess Costs which were incurred during such Post-Launch Quarter.

        "TRUE-UP AMOUNT". True-Up Amount means with respect to each of the
[**]through the [**] Post-Launch Years, an amount equal to the product of the
Economic Interest Variance for such Post-Launch Year multiplied by the sum of
the New Excess Costs for the [**] Post-Launch Quarter and each additional
Post-Launch Quarter thereafter, through the [**] Post-Launch Quarter in such
Post-Launch Year.

OPERATIVE PROVISIONS:

B.      OFFSETS AGAINST COMMERCIAL MILESTONE PAYMENTS

        1.      SANDOZ'S [**]% PROFIT MINIMUM. The Commercial Milestone
Payment(s) shall be the lesser of (a) the Full Milestone Payment(s) which is to
be made (in accordance with the timing in Section 4.10.2(b) for an applicable
Milestone Payment Quarter, or (b) the remainder after (i) the aggregate portions
of Profits paid to Momenta (excluding the effects of subsections C and E of this
SCHEDULE 4.3) for all Post-Launch Quarters (including the then-current Milestone
Payment Quarter) after the most recent prior Milestone Payment Quarter (or, if
no prior Milestone Payment Quarter has occurred, all Post-Launch Quarters), are
deducted from (ii) [**]percent ([**]%) of the aggregate Profits for all
Post-Launch Quarters (including the then-current Milestone Payment Quarter)
after the most recent prior Milestone Payment Quarter (or, if no prior Milestone
Payment Quarter has occurred, all Post-Launch Quarters). FOR EXAMPLE, IF FINAL
LEGAL CLEARANCE IS ACHIEVED PRIOR TO THE [**] ANNIVERSARY OF THE U.S. LAUNCH AND
[**], AND IF PROFITS FOR THE [**] POST-LAUNCH QUARTERS ARE U.S.$[**], THEN
MOMENTA'S PORTION OF THE PROFITS WOULD BE U.S.$[**]. THE COMMERCIAL MILESTONE
PAYMENT WOULD BE REDUCED TO U.S. $[**] (I.E., THE LESSER OF (a) U.S.$[**] OR (b)
U.S.$[**] (I.E., U.S.$[**] - U.S.$[**] ([**]% OF THE U.S.$[**] PROFITS MINUS THE
PORTION OF PROFITS DUE TO MOMENTA))).

        2.      CARRYFORWARD AND MOMENTA SHARE OF EXCESS COSTS DEDUCTION. After
the provisions of subsection B.1 of this SCHEDULE 4.3 have been applied, if
there are New Excess Costs with respect to the Milestone Payment Quarter or a
Carryforward exists at the start of such Milestone Payment Quarter, then the
amounts of the Carryforward and the Momenta Share of Excess Costs with respect
to such Post-Launch Quarter shall first be applied to reduce the amount of the
Commercial Milestone Payment to be paid by Sandoz, and any Carryforward or
Momenta Share of Excess Costs remaining with respect to such Post-Launch Quarter
after the applicable Milestone Payment(s) has been reduced to zero in accordance
with this subsection B.2 shall then be applied in accordance with the provisions
of subsection C of this SCHEDULE 4.3.

                                      -73-
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C.      OFFSETS AGAINST PAYMENTS OF PROFIT INTEREST AND ROYALTIES

        1.      FULL MILESTONE PAYMENT DEDUCTION. If, pursuant to subsection B.1
of this SCHEDULE 4.3, the Commercial Milestone Payment(s) to be paid in a
Milestone Payment Quarter is equal to the applicable Full Milestone Payment(s),
the Profit Interest for such Post-Launch Quarter shall be adjusted to equal the
product of (a) [**] percent ([**]%) times (b) the remaining Profits after such
Full Milestone Payment(s) are deducted from Profits in the U.S. Territory for
the applicable Post-Launch Quarter.

        2.      NEW EXCESS COSTS DEDUCTION. If New Excess Costs exist with
respect to a Post-Launch Quarter, and Sandoz does not exercise its right to
terminate the Agreement pursuant to Section 11.5 (if applicable), then, to the
extent any Momenta Share of Excess Costs were not applied in full to reduce the
amount of the Commercial Milestone Payment(s) pursuant to subsection B.2 of this
SCHEDULE 4.3, the amount of any Profit Interest or royalties, as the case may
be, otherwise payable to Momenta for such Post-Launch Quarter shall be reduced
by the applicable Momenta Share of Excess Costs for such Post-Launch Quarter,
subject to the provisions of subsection D of this SCHEDULE 4.3.

        3.      CARRYFORWARD DEDUCTION. If a Carryforward exists with respect to
a Post-Launch Quarter, then, to the extent such Carryforward was not applied in
full to reduce the amount of the Commercial Milestone Payment pursuant to
subsection B.2 of this SCHEDULE 4.3, the amount of any Profit Interest or
royalties, as the case may be, otherwise payable to Momenta for such Post-Launch
Quarter shall be reduced by the applicable remaining Carryforward, subject to
the provisions of subsection D of this SCHEDULE 4.3.

D.      [**]% REDUCTION FLOOR

        1.      DEDUCTION LIMIT. With respect to any Post-Launch Quarter, the
deduction of the Momenta Share of Excess Costs for such Post-Launch Quarter, the
Carryforward and the True-Up Amount for such Post-Launch Quarter, collectively,
shall not reduce by more than [**]percent ([**]%) the portion of Profits
otherwise payable to Momenta for such Post-Launch Quarter under Sections 4.5 or
4.8 or the royalties otherwise payable to Momenta for such Post-Launch Quarter
under Sections 4.6, 4.7 or 4.8, as applicable, and any portion of the Momenta
Share of Excess Costs for such Post-Launch Quarter or the True-Up Amount for
such Post-Launch Quarter not deducted from Profits or royalties payable to
Momenta as a result of such limitation shall be added to the Carryforward for
subsequent Post-Launch Quarters.

E.      MOMENTA ECONOMIC INTEREST TRUE-UP.

        1.      OVERPAYMENT BY MOMENTA. If the Economic Interest Variance for a
Post-Launch Year is negative, then the Sandoz Parties shall pay to Momenta,
within forty-five (45) days after the end of such Post-Launch Year, an amount
equal to the absolute value of the True-Up Amount for such Post-Launch Year.

        2.      UNDERPAYMENT BY MOMENTA. If the Economic Interest Variance for a
Post-Launch Year is positive, then, prior to the payment of any portion of
Profits or the royalties to Momenta

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                                                                  EXECUTION COPY

with respect to the last Post-Launch Quarter in such Post-Launch Year, the
True-Up Amount for such Post-Launch Year shall first be deducted from the
portion of Profits or the royalties otherwise payable to Momenta for such last
Post-Launch Quarter in such Post-Launch Year, subject to the provisions of
subsection D of this SCHEDULE 4.3.

F.      EXAMPLES

THE FOLLOWING EXAMPLES ARE FOR ILLUSTRATIVE PURPOSES ONLY. Any errors or
omissions in this section should not be construed to change the meaning of the
rest of this SCHEDULE 4.3 or this Agreement. Figures 4.3(a) and 4.3(b) provide
spreadsheets with calculations through the [**] Post-launch Year.

ASSUMPTIONS. Net Sales, Manufacturing Costs, Selling Expenses, and New Excess
Costs are as reported in Figures 4.3(a) and 4.3(b). It is assumed for this
example that [**] until the beginning of the [**] Post-Launch Year (it is
assumed that [**] as of the first day of the [**] Launch Year and is not [**]).
It is also assumed that First Commercial Sale of the Product occurs part-way
through the [**] Post-Launch Quarter. Finally, it is assumed that First
Commercial Sale does not occur until after Final Legal Clearance in Figure
4.3(a), and that Final Legal Clearance occurs during the [**] Quarter of the
[**] Post-Launch Year in Figure 4.3(b). All numbers are reported to two decimal
points for ease of illustration and except as otherwise specified represent
millions of US dollars.

CALCULATIONS FOR FIGURE 4.3(a) (WORKING COLUMN BY COLUMN FROM LEFT TO RIGHT).

PROFIT. The total Profit is calculated by subtracting Manufacturing Costs and
Selling Expenses from Net Sales.

PRELIMINARY PROFIT/ROYALTY CALCULATION 1. The column entitled Preliminary
Profit/Royalty Calculation 1 (taking into account only Net Sales, Manufacturing
Costs, Selling Expenses and Third Party Competitor status), is calculated, based
on the assumptions listed above, as [**]% of Profits until a Third Party
Competitor exists at the beginning of the [**] Post-Launch Year, and then as
tiered Post-[**] Royalty rates on Net Sales of [**]% and [**]%, as applicable.

MOMENTA ECONOMIC INTEREST. In the first [**] Post-Launch Years, the Momenta
Economic Interest is calculated as the lesser of the Actual Momenta Economic
Interest or the Estimated Momenta Economic Interest (as described in subsection
A of this SCHEDULE 4.3). As an example, Actual Momenta Economic Interest in the
[**] Quarter of the [**] Post-Launch Year is calculated as follows. The sum of
the Profit/Royalty payable to Momenta (as calculated in the previous column) for
all Quarters from U.S. Launch through the [**] Quarter of the [**] Post-Launch
Year ($[**]) is divided by the sum of the Profits for the Product over the same
period ($[**]) to yield [**]%. Since this is less than the Estimated Momenta
Economic Interest of [**]% for that same Quarter, the Momenta Economic Interest
is [**]%. In the Sixth and subsequent Post-Launch Years, the Momenta Economic
Interest is calculated as described in subsection A of this SCHEDULE 4.3.

                                      -75-
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COMMERCIAL MILESTONE PAYMENT. The first Commercial Milestone Payment in the
illustration is reduced for two reasons. First, the Sandoz Parties' portion of
Profits would be less than [**]% if the full $[**] Commercial Milestone Payment
was made. Therefore, the Commercial Milestone is reduced as follows. [**]% of
the Profits since the last Milestone Payment Quarter (or since U.S. Launch in
this case, since it is the first Commercial Milestone Payment) is calculated.
Here, the total Profits are $[**], and [**]% of the sum of such Profits for the
[**] through the [**] Post-Launch Quarters is $[**]. From this [**]% of the
$[**] in Profits is subtracted any Profit/royalty payments made to Momenta
(excluding the effects of subsections C and E of this SCHEDULE 4.3) during the
same [**] Quarters (in this case, Profit payments, which total $[**]), resulting
in $[**]. This $[**] is the Commercial Milestone Payment adjusted for the
provision that ensures the Sandoz Parties' minimum [**]% Profit share
(subsection B.1 of this SCHEDULE 4.3). The first Commercial Milestone Payment is
then further adjusted (as described in subsection B.2 of this SCHEDULE 4.3) by
subtracting $[**] for the Momenta Share of Excess Costs in that Quarter,
resulting in a final adjusted Commercial Milestone Payment of $[**]. The second
and third Commercial Milestone Payments do not require similar adjustments and
are both $[**].

PRELIMINARY PROFIT/ROYALTY CALCULATION 2. The Preliminary Profit/Royalty
Calculation 2 in the next column now includes the impact of any deductions made
as a result of the Commercial Milestone Payments. Note that the first Commercial
Milestone Payment which is reduced due to the provision related to the Sandoz
Parties' [**]% Profit minimum, as described above, is not subtracted in the
Profit calculation (as described in subsection C of this SCHEDULE 4.3). The
second and third Commercial Milestone Payments, which are full $[**] payments,
are subtracted.

MOMENTA SHARE OF EXCESS COSTS. Momenta Share of Excess Costs are calculated by
multiplying New Excess Costs in the applicable Quarter by the applicable Momenta
Economic Interest for that same Quarter.

TRUE UP AMOUNT. The True-Up Amount is calculated by multiplying the Economic
Interest Variance by the sum of all previous Quarters' (but not including the
current Quarter's) New Excess Costs. For example, in Q4 of the [**] Post-Launch
Year, the Economic Interest Variance of [**]% ([**]%-[**]%) is multiplied by the
sum of $[**], $[**], and $[**] (but not $[**]) to yield $[**].

PRELIMINARY PROFIT/ROYALTY CALCULATION 3. The Preliminary Profit/Royalty
Calculation 3 in the next column now takes into account both the Momenta Share
of Excess Costs and the True-Up Amount. Note that in the [**] Post-launch
Quarter, the Momenta Share of Excess Costs would reduce the payment by more than
[**]%. Hence (as described in subsection D of this SCHEDULE 4.3), the payment
amount is only reduced here from $[**] to [**]% of this amount, or $[**] Thus
only $[**] of the $[**] of the Momenta Share of Excess Costs is paid in this
Quarter. The remaining $[**] becomes part of the Carryforward.

CARRYFORWARD AND FINAL PROFIT/ROYALTY CALCULATION. Carryforwards are subtracted
from the Preliminary Profit/Royalty Calculations 3 in the previous column to
complete the Final Profit/Royalty Calculation.

                                      -76-
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                                                                  EXECUTION COPY

DIFFERENCES IN CALCULATIONS FOR FIGURE 4.3(b). Except as provided in this
paragraph, the assumptions and calculations of Figure 4.3(a) apply to Figure
4.3(b). In Figure 4.3(b), Final Legal Clearance occurs during the first Quarter
of the [**] Post-Launch Year. As a result, no Commercial Milestone Payments are
made in the first Quarter of the [**] Post-Launch Year or in the first Quarter
of the [**] Post-Launch Year. In the first Quarter of the [**] Post-Launch Year,
the Momenta Share of Excess Costs is deducted from the Preliminary
Profit/Royalty Calculation 2 rather than from the Commercial Milestone Payment.
Finally, the Commercial Milestone Payment in Figure 4.3(b) is made in the
Quarter that Final Legal Clearance occurs. The payment is calculated according
to subsection B.1 of this SCHEDULE 4.3. This payment is also subtracted from
Profits to calculate the Preliminary Profit/Royalty 2 for the first Quarter of
the [**] Post-Launch Year in accordance with subsection C.1 of this SCHEDULE
4.3.

                                      -77-
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                                                                EXECUTION COPY

                             Figure 4.3(a) (page 1)

<Table>
<Caption>
                                                                            Preliminary
                                                                 Profit    Profit/Royalty    Momenta
            Net     Third Party   Manufacturing    Selling     (total for   Calculation      Economic        COMMERCIAL
           Sales    Competitor        Costs        Expenses     product)         1           Interest        MILESTONE
        -------------------------------------------------------------------------------------------------------------------
<S>        <C>         <C>             <C>           <C>          <C>           <C>            <C>             <C>
Q1 Yr 1    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q2 Yr 1    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q3 Yr 1    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q4 Yr 1    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q1 Yr 2    [**]        [**]            [**]          [**]         [**]          [**]           [**]%           [**]
Q2 Yr 2    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q3 Yr 2    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q4 Yr 2    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q1 Yr 3    [**]        [**]            [**]          [**]         [**]          [**]           [**]%           [**]
Q2 Yr 3    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q3 Yr 3    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q4 Yr 3    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q1 Yr 4    [**]        [**]            [**]          [**]         [**]          [**]           [**]%           [**]
Q2 Yr 4    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q3 Yr 4    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q4 Yr 4    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q1 Yr 5    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q2 Yr 5    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q3 Yr 5    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q4 Yr 5    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q1 Yr 6    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q2 Yr 6    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q3 Yr 6    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q4 Yr 6    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q1 Yr 7    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q2 Yr 7    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q3 Yr 7    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q4 Yr 7    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
</Table>

                                      -78-
<Page>

                                                                  EXECUTION COPY

                             Figure 4.3(a) (page 2)

<Table>
<Caption>
          Preliminary                                                 Preliminary
        Profit/Royalty                      Momenta                  Profit/Royalty                                      FINAL
          Calculation         New          Share of                   Calculation        New          Cummulative    PROFIT/ROYALTY
              2          Excess Costs    Excess Costs     True Up          3         Carryforward    Carryforward     CALCULATION
        ---------------------------------------------------------------------------------------------------------------------------
<S>           <C>             <C>            <C>            <C>           <C>            <C>             <C>              <C>
Q1 Yr 1       [**]            [**]           [**]                         [**]           [**]            [**]             [**]
Q2 Yr 1       [**]                                                        [**]                           [**]             [**]
Q3 Yr 1       [**]                                                        [**]                                            [**]
Q4 Yr 1       [**]                                          [**]          [**]                                            [**]
Q1 Yr 2       [**]            [**]           [**]                         [**]                                            [**]
Q2 Yr 2       [**]                                                        [**]                                            [**]
Q3 Yr 2       [**]                                                        [**]                                            [**]
Q4 Yr 2       [**]            [**]           [**]           [**]          [**]                                            [**]
Q1 Yr 3       [**]                                                        [**]                                            [**]
Q2 Yr 3       [**]                                                        [**]                                            [**]
Q3 Yr 3       [**]                                                        [**]                                            [**]
Q4 Yr 3       [**]            [**]           [**]           [**]          [**]                                            [**]
Q1 Yr 4       [**]                                                        [**]                                            [**]
Q2 Yr 4       [**]                                                        [**]                                            [**]
Q3 Yr 4       [**]                                                        [**]                                            [**]
Q4 Yr 4       [**]                                          [**]          [**]                                            [**]
Q1 Yr 5       [**]                                                        [**]                                            [**]
Q2 Yr 5       [**]                                                        [**]                                            [**]
Q3 Yr 5       [**]                                                        [**]                                            [**]
Q4 Yr 5       [**]                                          [**]          [**]                                            [**]
Q1 Yr 6       [**]                                                        [**]                                            [**]
Q2 Yr 6       [**]            [**]           [**]                         [**]                                            [**]
Q3 Yr 6       [**]                                                        [**]                                            [**]
Q4 Yr 6       [**]                                                        [**]                                            [**]
Q1 Yr 7       [**]                                                        [**]                                            [**]
Q2 Yr 7       [**]                                                        [**]                                            [**]
Q3 Yr 7       [**]                                                        [**]                                            [**]
</Table>

                                      -79-
<Page>

                                                                  EXECUTION COPY

<Table>
<S>           <C>             <C>            <C>            <C>           <C>            <C>             <C>              <C>
Q4 Yr 7       [**]                                                        [**]                                            [**]
</Table>

                                      -80-
<Page>

                                                                  EXECUTION COPY

                             Figure 4.3(b) (page 1)

<Table>
<Caption>
                                                                            Preliminary
                                                                 Profit    Profit/Royalty    Momenta
            Net     Third Party   Manufacturing    Selling     (total for   Calculation      Economic        COMMERCIAL
           Sales    Competitor        Costs        Expenses     product)         1           Interest        MILESTONE
        -------------------------------------------------------------------------------------------------------------------
<S>        <C>         <C>             <C>           <C>          <C>           <C>            <C>               <C>
Q1 Yr 1    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q2 Yr 1    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q3 Yr 1    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q4 Yr 1    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q1 Yr 2    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q2 Yr 2    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q3 Yr 2    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q4 Yr 2    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q1 Yr 3    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q2 Yr 3    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q3 Yr 3    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q4 Yr 3    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q1 Yr 4    [**]        [**]            [**]          [**]         [**]          [**]           [**]%             [**]
Q2 Yr 4    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q3 Yr 4    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q4 Yr 4    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q1 Yr 5    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q2 Yr 5    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q3 Yr 5    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q4 Yr 5    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q1 Yr 6    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q2 Yr 6    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q3 Yr 6    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q4 Yr 6    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q1 Yr 7    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q2 Yr 7    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q3 Yr 7    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
Q4 Yr 7    [**]        [**]            [**]          [**]         [**]          [**]           [**]%
</Table>

                                      -81-
<Page>

                             Figure 4.3(b) (page 2)

<Table>
<Caption>
          Preliminary                                                  Preliminary
        Profit/Royalty                       Momenta                  Profit/Royalty                                     FINAL
          Calculation         New           Share of                   Calculation         New         Cummulative   PROFIT/ROYALTY
              2           Excess Costs    Excess Costs     True Up          3         Carryforward    Carryforward     CALCULATION
        ---------------------------------------------------------------------------------------------------------------------------
<S>          <C>              <C>             <C>           <C>            <C>            <C>             <C>              <C>
Q1 Yr 1      [**]             [**]            [**]                         [**]           [**]            [**]             [**]
Q2 Yr 1      [**]                                                          [**]                           [**]             [**]
Q3 Yr 1      [**]                                                          [**]                                            [**]
Q4 Yr 1      [**]                                           [**]           [**]                                            [**]
Q1 Yr 2      [**]             [**]            [**]                         [**]                                            [**]
Q2 Yr 2      [**]                                                          [**]                                            [**]
Q3 Yr 2      [**]                                                          [**]                                            [**]
Q4 Yr 2      [**]             [**]            [**]          [**]           [**]                                            [**]
Q1 Yr 3      [**]                                                          [**]                                            [**]
Q2 Yr 3      [**]                                                          [**]                                            [**]
Q3 Yr 3      [**]                                                          [**]                                            [**]
Q4 Yr 3      [**]             [**]            [**]          [**]           [**]                                            [**]
Q1 Yr 4      [**]                                                          [**]                                            [**]
Q2 Yr 4      [**]                                                          [**]                                            [**]
Q3 Yr 4      [**]                                                          [**]                                            [**]
Q4 Yr 4      [**]                                           [**]           [**]                                            [**]
Q1 Yr 5      [**]                                                          [**]                                            [**]
Q2 Yr 5      [**]                                                          [**]                                            [**]
Q3 Yr 5      [**]                                                          [**]                                            [**]
Q4 Yr 5      [**]                                           [**]           [**]                                            [**]
Q1 Yr 6      [**]                                                          [**]                                            [**]
Q2 Yr 6      [**]             [**]            [**]                         [**]                                            [**]
Q3 Yr 6      [**]                                                          [**]                                            [**]
Q4 Yr 6      [**]                                                          [**]                                            [**]
Q1 Yr 7      [**]                                                          [**]                                            [**]
Q2 Yr 7      [**]                                                          [**]                                            [**]
Q3 Yr 7      [**]                                                          [**]                                            [**]
</Table>

                                      -82-
<Page>

<Table>
<S>          <C>              <C>             <C>           <C>            <C>            <C>             <C>              <C>
Q4 Yr 7      [**]                                                          [**]                                            [**]
</Table>

                                      -83-
<Page>

                                                                  EXECUTION COPY

                                  SCHEDULE 5.8
                           ANNUAL COLLABORATION PLAN:
      PRELIMINARY LIST OF ACTIVITIES AND ASSIGNMENT OF LEAD RESPONSIBILITY
                                  TO PARTY(IES)

<Table>
<Caption>
FUNCTIONAL AREA       ACTIVITY                                                  LEAD
---------------       --------                                                  ----
<S>                   <C>                                                       <C>
TECHNOLOGY /          Support [**]                                              [**]
CHARACTERIZATION      Complete [**] the Product
                      Continue to [**] the Product approval

REGULATORY            Prior to [**] the Product                                 [**]
                      -- Manage [**]
                      [**]-- [**] the Product
                      -- manage [**],
                         [**]-- submit [**]
                      -- [**]

PRE-CLINICAL /        Design [**] the Product and Product commercialization     [**]
CLINICAL

MANUFACTURING         [**]-- research [**]                                      [**]
                      --  secure [**]
                      [**]-- [**] process [**]
                      -- [**] and stability
                      -- [**] and stability
                      -- [**] support [**]
                      -- [**] stability
                      -- successful [**]
                      -- commercial [**]
                      -- commercial [**]
                      [**]-- [**]-- [**] and stability
                      -- [**] and stability
                      -- [**] methods [**]
                      -- manage [**]

LEGAL                 [**]-- to support [**]                                    [**]
                      [**] Litigation

COMMERCIAL            Pre-Launch Marketing Strategy and Plan                    [**]
                      Product Launch and Commercialization
</Table>

S =   Sandoz
M =   Momenta
S/M = Lead to be defined between Sandoz or Momenta by JPT

                                      -84-

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