Document:

3rd Amendment of Amgen Retirement & Savings Plan

 Exhibit 10.1 
  
 THIRD AMENDMENT TO THE 
 AMGEN RETIREMENT AND SAVINGS PLAN 
 (AS AMENDED AND RESTATED EFFECTIVE AS OF JANUARY 1, 2003)

  
 1. Section 2.51 of the Amgen Retirement and Savings Plan (As Amended and
Restated Effective as of January 1, 2003) (the “Plan”) is hereby amended and restated effective January 1, 2005, as follows: 
  

	 	“2.51	‘Year of Service’ means, for purposes of vesting prior to January 1, 2002, each Plan Year or portion thereof during which an Employee was credited with at least
1,000 Hours of Service.” 

  
 2. Subsection 3.3(b) of the Plan
is hereby amended and restated effective January 1, 2005, as follows: 
  

	 	“(b)	Unless excluded under (c) below, an individual classified by a Participating Company as a ‘regular part-time employee’ is an Eligible Employee.”

  
 3. Subsection 3.3(c) of the Plan is hereby amended and restated
effective as of January 1, 2003, as follows: 
  

	 	“(c)	Excluded Individuals. An individual shall not be an Eligible Employee for any period in which he or she is: 

  

	 	(1)	Included in a unit of employees covered by a collective-bargaining agreement that does not provide that such individual shall be eligible to participate in the Plan;

  

	 	(2)	Not on the Payroll of a Participating Company, even though such person may be deemed, for any reason, to be an employee; 

  

	 	(3)	Subject to an oral or written agreement that provides that such individual shall not be eligible to participate in the Plan; 

  

	 	(4)	Employed by a non-U.S. subsidiary of the Company; 

  

	 	(5)	Classified by a Participating Company as a ‘leased employee’ (within the meaning of Section 414(n) of the Code) with respect to such Participating Company or would be so
classified but for the period-of-service requirement of Code Section 414(n)(2)(B); 

  

	 	(6)	Any person or entity (including a temporary employee, independent contractor, or consultant) for whom a Participating Company does not withhold federal income and employment taxes
from such person’s or entity’s compensation; or 

	 	(7)	Classified as an intern or co-op on a Participating Company’s Payroll. 

  

If, during any period, a Participating Company has not regarded an individual as an Employee and, for that reason, has not withheld employment taxes
with respect to that individual, then that individual shall not be an Eligible Employee for that period, even in the event that the individual is determined, retroactively, to have been an Employee during all or any portion of that period.”

  
 4. Section 3.4 of the Plan is hereby amended and restated effective January 1,
2005, as follows: 
  

	 	“3.4	Reserved.” 

  
 5. Section 3.5 of the Plan is hereby amended and restated effective as of January 1, 2004, as follows: 
  

	 	“3.5	Suspension of Membership. A Participant’s participation in the Plan shall be suspended for any period of time during which the Participant: 

  

	 	(a)	Neither receives nor is entitled to receive any Compensation, including (without limitation) any leave of absence without pay; or 

  

	 	(b)	Does not qualify as an Eligible Employee but remains a Participant. 

  
 A Participant shall not make Participant Elected Contributions or receive any allocation of Company Contributions with respect to a period of suspended
participation, but a suspended Participant’s Accounts shall remain invested as a part of the Trust Fund and shall continue to share in the gains, income, losses and expenses of the Trust Fund. 
  
 Notwithstanding the foregoing, in accordance with Sections 10.8 and 11.4,
participation is also suspended for 12 months (6 months, effective January 1, 2005) if a Participant defaults on a Plan loan or 6 months if a Participant takes a Hardship Withdrawal. A Participant shall not make Participant Elected Contributions or
receive any allocation of Matching Contributions with respect to a period of suspended participation following a Participant’s default on a Plan loan or taking of a Hardship Withdrawal, but a suspended Participant’s Accounts shall remain
invested as a part of the Trust Fund and shall continue to share in the gains, income, losses and expenses of the Trust Fund. Notwithstanding the foregoing, a Participant who is suspended in accordance with Section 10.8 and 11.4 shall continue to
receive an allocation of Nonelective Contributions during the period of suspended participation.” 
  
 6. Section 4.5 of the Plan is hereby amended effective as of January 1, 2002 by adding the following sentence at the end of the first paragraph thereof: 
  
 “Notwithstanding the foregoing, the Plan will not accept Rollover Contributions that include after-tax contributions,
unless the Rollover Contributions were previously accepted by and included in the assets of a qualified retirement plan that is subsequently merged into this Plan.” 
  

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 7. Section 5.1 of the Plan is hereby amended and restated effective as of January 1, 2004, as follows: 
  

	 	“5.1	Matching Contributions. 

  

	 	(a)	Subject to the limitations of Section 4.6, Section 5.6 and Articles 13-15, each Participating Company may, in its discretion, make Matching Contributions in an amount determined by
the Participating Company. A Matching Contributions formula may limit the amount of Participant Elected Contributions that are taken into account for purposes of allocating Matching Contributions or may limit allocations of Matching Contributions to
a specified group of Participants; provided, however, that the Matching Contribution formula(s) shall not discriminate in favor of Highly Compensated Employees. A Matching Contribution shall be paid to the Trustee as soon as reasonably practicable
after the pay period to which it relates and shall be allocated to the Accounts of Participants as provided in Section 6.5. 

  

	 	(b)	If a Participant ceases making Participant Elected Contributions before the full amount of Matching Contributions allowed for in the preceding paragraph have been made on behalf of
such Participant for a calendar quarter, a ‘true-up’ Matching Contribution shall be made on behalf of such Participant if the Participant is employed by a Participating Company on the last day of the calendar quarter. The amount of the
‘true-up’ Matching Contribution shall be the amount of the Matching Contribution allowed for on behalf of the Participant by the preceding paragraph less the amount of the Matching Contribution actually made on behalf of the Participant
for the calendar quarter, subject to such administrative procedures as the Participating Company may establish to reflect payroll periods that end on other than the last day of a calendar quarter. True-up Matching Contributions shall be made by each
Participating Company as soon administratively practicable following the end of each calendar quarter, but in no event later than the time prescribed by law. 

  

	 	(c)	Notwithstanding Subsection (b) above, if a Participant ceases making Participant Elected Contributions before the full amount of Matching Contributions allowed for in the first
paragraph above have been made on behalf of such Participant for the period between January 1, 2004 and the pay period ending immediately prior to September 30, 2004, a ‘true-up’ Matching Contribution shall be made on behalf of such
Participant regardless of whether such Participant is still employed by a Participating 

  

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 Company on September 30, 2004. The amount of the ‘true-up’ Matching Contribution shall be the
amount of the Matching Contribution allowed for on behalf of the Participant by the first paragraph above less the amount of the Matching Contribution actually made on behalf of the Participant during the period between January 1, 2004 and pay
period ending immediately prior to September 30, 2004. True-up Matching Contributions shall be made by each Participating Company as soon administratively practicable following September 30, 2004, but in no event later than the time prescribed by
law.” 
  
 8. Section 5.2 of the Plan is hereby amended and restated effective
as of January 1, 2004, as follows: 
  

	 	“5.2	Nonelective Contributions. 

  

	 	(a)	Subject to the limitations in Section 5.6 and Articles 13-15, a Participating Company shall make Nonelective Contributions on behalf of each Participant who satisfies the
eligibility requirements of Section 3. The Nonelective Contribution shall be an amount equal to 5% of each Participant’s Compensation and shall be allocated as of each pay period. For purposes of allocating such Nonelective Contributions for
any Plan Year or other allocation period based on an Employee’s Compensation, only Compensation attributable to periods in such Plan Year or other allocation period during which such Employee was an Eligible Employee shall be taken into
account. Nonelective Contributions shall be paid to the Trustee as soon as reasonably practicable following the close of the pay period to which it relates. 

  

	 	(b)	With respect to the Nonelective Contribution, which is intended to constitute a ‘nonelective contribution’ under Code Section 401(k)(12) (i.e., a ‘safe harbor
contribution’), the Company shall distribute within a reasonable period prior to each Plan Year, an ‘annual safe harbor notice’ in accordance with the guidance issued by the Internal Revenue Service with respect to such notices. To
the extent the Company elects to amend the Plan to freeze (or thereafter reinstate) Nonelective Contributions with respect to subsequent Plan Years, the Company shall timely notify Eligible Employees in accordance with the guidance issued by the
Internal Revenue Service. At a minimum the annual safe harbor notice shall: 

  

	 	(1)	Be sufficiently accurate and comprehensive to inform the Eligible Employee of his or her rights and obligations under the Plan; 

  

	 	(2)	Be written in a manner calculated to be understood by the average Employee Eligible to participate in the Plan, and shall describe: 

  

	 	(A)	the Nonelective Contribution formula used under the Plan; 

  

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	 	(B)	any other contributions under the Plan (including the potential for discretionary matching contributions) and the conditions under which such contributions are made;

  

	 	(C)	the type and amount of Compensation that may be deferred under the Plan; 

  

	 	(E)	how to make Participant Elected Contribution elections, including any administrative requirements that apply to such elections; 

  

	 	(F)	the periods available under the Plan for making Participant Elected Contributions; 

  

	 	(G)	withdrawal and vesting provisions applicable to contributions under the Plan; and 

  

	 	(H)	Information that makes it easy to obtain additional information about the Plan (including an additional copy of the summary plan description) such as telephone numbers, addresses
and, if applicable, electronic addresses, of individuals or offices from whom Employees can obtain such Plan information. 

  

	 	(c)	Notwithstanding the foregoing and subject to the limitations in Section 5.6 and Articles 13-15, each Participating Company may, in its discretion, make a special Nonelective
Contribution to each Participant who in his or her initial year of employment with the Participating Company may not make the maximum Participant Elected Contributions permitted under the Plan because in the same Plan Year he or she previously made
pre-tax salary deferrals under a prior, unrelated employer’s qualified plan. The amount of the special Nonelective Contribution shall be determined by the Participating Company. Such Nonelective Contributions shall be allocated as a percent of
each eligible Participant’s Compensation. The special Nonelective Contribution shall only be made on behalf of Participants that are Nonhighly Compensated Employees (as defined in Section 12.3).” 

  
 9. Section 6.6 of the Plan is hereby amended effective as of January 1, 2004, by deleting the
last two sentences thereof. 
  
 10. Section 8.10 of the Plan is hereby amended
effective as of January 1, 2003, by substituting the following sentence for the first sentence thereof: 
  
 “Subject to Section 8.11, a Participant’s Beneficiary shall be the person(s), estate or trust(s) so designated by the Participant.”

  

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	11.	Section 8.13 of the Plan is amended and restated effective January 1, 2005, as follows: 

  

	 	“8.13	Incompetency. Whenever and as often as any person entitled to receive a distribution under the Plan shall be under a legal disability or, in the sole judgment of the Company,
shall otherwise be unable to care for such distributions to the person’s own best interest and advantage, the Company, in the exercise of its discretion, may direct such distributions to be made in any one or more of the following ways:

  

	 	(a)	directly to such person; 

  

	 	(b)	to such person’s spouse; 

  

	 	(c)	to such person’s legal guardian or conservator; or 

  

	 	(d)	to any other person to be held and used for such person’s benefit. 

  
 The decision of the Company shall, in each case, be final and binding upon all parties, and any distribution made pursuant to the power herein conferred
on the Company shall, to the extent so made, be a complete discharge of the obligations under the Plan of the Participating Companies, the Trustee and the Plan Administrator with respect to such person.” 
  
 12. Section 9.2 of the Plan is hereby amended effective as of January 1, 2003, by
substituting the following sentence for the third sentence thereof: 
  
 “The transfers to the Alternate Payee Accounts shall be made pro rata from the Participant’s Accounts.” 
  
 13. Section 9.5 of the Plan is hereby amended effective as of January 1, 2003, by adding the following sentence after the last sentence thereof: 
  
 “Notwithstanding Section 8.6 of the Plan or any other provisions of the
Plan to the contrary, distributions to Alternate Payees shall only be made in the form of single sum distributions.” 
  
 14. Section 10.8 of the Plan is hereby amended effective January 1, 2005, by substituting the number “6” for the number “12” in the third sentence
thereof. 
  

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 15. Section 13.2 of the Plan is hereby amended effective as of January 1, 2004, by substituting the following sentence
for the first sentence thereof: 
  
 “The provisions of the
Plan (including this Section 13.2) that relate to the actual deferral percentage test, as provided in Code Section 401(k)(3) and the regulations issued thereunder, shall not apply unless the Participating Companies do not make Nonelective
Contributions that satisfy the safe harbor requirements of Code Section 401(k)(12) with respect to a Plan Year on behalf of each Nonhighly Compensated Employee who is an Eligible Employee.” 
  
 16. Section 13.2 of the Plan is hereby amended effective as of January 1, 2004, by
substituting the term “current” for the term “preceding” in each place that the latter term appears in Subsection (c) thereof. 
  
 17. Section 14.1 of the Plan is hereby amended effective as of January 1, 2004, by substituting the following sentence for the first sentence thereof: 
  
 “The provisions of the Plan (including this Section 14.1) that relate
to the actual contribution percentage test, as provided in Code Section 401(m)(2) and the regulations issued thereunder, shall not apply unless the Participating Companies do not make Nonelective Contributions that satisfy the safe harbor
requirements of Code Section 401(m)(11) with respect to a Plan Year on behalf of each Nonhighly Compensated Employee who is an Eligible Employee.” 
  
 18. Section 14.1 of the Plan is hereby amended effective as of January 1, 2004, by substituting the term “current” for the term “preceding” in each
place that the latter term appears in Subsection (c) thereof. 
  
 19. Section 16.4
of the Plan is hereby amended and restated effective as of January 1, 2003, as follows: 
  

	 	“16.4	Administrative Expenses. Except as otherwise explicitly stated in the Plan (including Sections 9.6, 10.6 and 11.6 hereof) and the Trust Agreement, the Participating Companies
or the Trust Fund shall pay the administrative expenses of the Plan and Trust Fund.” 

  
 20. Section 18.6 of the Plan is hereby amended and restated effective as of January 1, 2003, as follows: 
  

	 	“18.6	Exhaustion of Administrative Remedies. No legal or equitable action for benefits under the Plan shall be brought unless and until the claimant (a) has submitted a written
application for benefits in accordance with Section 18.1, (b) has been notified that the application is denied, (c) has filed a written request for a review of the application in accordance with Section 18.3, and (d) has been notified in writing or
electronically that the Fiduciary Committee has affirmed the denial of the application. Effective October 15, 2004, if the claimant has entered into an 

  

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 arbitration agreement with the Company or a Participating Company, the provisions of that arbitration
agreement will govern following the claimant’s compliance with the foregoing provisions of this Article 18, and shall be the sole and exclusive remedy following compliance with the foregoing provisions.” 
  
 To record this Third Amendment to the Plan as set forth herein, the Company has caused its
authorized Officer to execute this document this 7th day of October, 2004 
  

			
	 AMGEN INC.

		
	 By:
	 	 /s/ BRIAN MCNAMEE

		
	 Title:
	 	 Senior Vice President, Human Resources

  

 8Amgen Supplemental Retirement Plan

 Exhibit 10.2 
  
 AMGEN INC. SUPPLEMENTAL 
  
 RETIREMENT PLAN 
  
 (As Amended and Restated Effective January 1, 2005) 

 AMGEN SUPPLEMENTAL RETIREMENT PLAN 
 (As Amended and Restated Effective January 1, 2005) 
  
 ARTICLE I 
 INTRODUCTION AND PLAN PURPOSE 
  
 1.1 History, Purpose and Effective Date. The Amgen Supplemental Retirement Plan (the
“Plan”) was established by Amgen Inc. (the “Company”) effective as of January 1, 1993, was amended and restated effective January 1, 1998, and again effective November 1, 1999. The purpose of this Plan is to provide benefits to
employees of the Company and certain of its affiliates and subsidiaries whose Matching Contributions and Nonelective Contributions are limited under the Amgen Inc. Retirement and Savings Plan (the “Retirement Plan”), whether because of
statutory limitations or because of employee deferrals to the Amgen Nonqualified Deferred Compensation Plan (the “NQDC”), or both. The Company intends that the Plan will provide benefits to a select group of management or highly
compensated employees. The following provisions constitute and amendment and restatement of the Plan generally effective January 1, 2005, unless a different effective date is stated herein. 
  
 1.2 Merger of Immunex Plan. Effective January 1, 2005, the Immunex Key Employee Plan
(the “Immunex Plan”) is merged with and into the Plan. As of such date, the balances of each participant’s account in the Immunex Plan will be transferred to this Plan and credited to a separate account in the Participant’s name.
Thereafter, such account will be subject to the provisions of this Plan, including the earnings provisions of Section 4.3 and the distribution provisions of Article V, unless specifically provided otherwise in the Plan. 
  
 ARTICLE II 
 DEFINITIONS 
  
 For the purposes of this Plan, the following terms, when capitalized, have the following meanings. Any capitalized term in this Plan that is not defined in this Article II has the meaning given such term in the Retirement Plan. 

 
 2.1 Account means the Account maintained by the Company in accordance with Article
IV with respect to Plan Credits and Earnings. 
  
 2.2 Beneficiary means the
person, persons or entity entitled under Article VI to receive Plan benefits payable in the event of your death. 
  
 2.3 Board means the Board of Directors of the Company. 
  
 2.4 Code means the Internal Revenue Code of 1986, as amended. 
  

 1 

 2.5 Committee means the Compensation Committee of the Company’s Board. 
  
 2.6 Company means Amgen Inc. or any subsidiary or affiliate of Amgen Inc. selected by
the Board or the Committee to participate in the Plan and excludes any disregarded entity pursuant to Treasury Regulations section 301.7701-3, unless such disregarded entity is selected by the Board or Committee to participate in the Plan.

  
 2.7 Compensation has the same meaning as such term has under the
Retirement Plan, except that, for purposes of this Plan, Compensation is not limited by the Salary Cap, includes amounts that are deferred into the NQDC. 
  
 2.8 Deferral Commitment means the election to defer “Participant Elected Contributions,” as described in the Retirement Plan. 
  
 2.9 Earnings means the amount credited to your Account under Section 4.3 of the Plan.

  
 2.10 Immunex Account means the account established to record account
balances that were transferred from the Immunex Plan, and Earnings thereon. Your Immunex Account will be credited with Earnings in accordance with Section 4.3 and, except as specifically provided otherwise in the Plan, will be subject to the
distribution provisions of Article V. 
  
 2.11 Normal Retirement Date means
the first day of the month coinciding with or next following your attainment of age 65. 
  
 2.12 NQDC means the Amgen Nonqualified Deferred Compensation Plan. 
  
 2.13 Participation Agreement means the agreement you file with the Committee acknowledging the terms of the Plan and enrolling in the Plan. 
  
 2.14 Plan means this Amgen Inc. Supplemental Retirement Plan. 
  
 2.15 Plan Credits means the amount credited to your Account under Section 4.2 and, where applicable, also includes Core Credits and Matching Credits that were made
to your Account for periods prior to January 1, 2005. 
  
 2.16 Retirement
Plan means the Amgen Inc. Retirement and Savings Plan. 
  
 2.17 Salary
Cap means the highest level of compensation that can be considered for the purpose of calculating benefits under Section 401(a)(17) of the Code. 
  
 2.18 Spouse means your wife or husband who is lawfully married to you at the time of your death. 
  

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 2.19 Years of Service means, effective April 1, 2004, a continuous period of employment beginning on your date of
hire with the Company and ending on the date your employment with the Company terminates for any reason. You will be credited with one Year of Service for each consecutive 12-month-period beginning on your hire date, and each anniversary thereof,
that you remain employed with the Company. If your employment with the Company terminates and you are later rehired, your prior Years of Service under the Plan will be disregarded and your Years of Service for purposes of vesting in Plan Credits
after the rehire date will be determined from the date of your rehire until your subsequent termination of employment. 
  
 ARTICLE III 
 ELIGIBILITY AND
PARTICIPATION 
  
 3.1 Eligibility. You are eligible to receive
credits in your Account as provided in Section 4.2 of the Plan during the time you are eligible to participate in the Retirement Plan and either your Compensation for the relevant calendar year is in excess of the Salary Cap, or you elect to make a
deferral into the NQDC, or both. 
  
 3.2 Automatic Participation. Once you
satisfy the eligibility requirements under Section 3.1, you will automatically be enrolled in the Plan and eligible to receive Plan Credits under Article IV of the Plan. 
  
 3.3 Participation. After you first become eligible, you will continue to participate in the Plan (that is, you will receive Earnings
on the balance in your Account) as long as you have not received a distribution of your Account, even if you are no longer eligible to receive credits under the Plan. 
  
 ARTICLE IV 
 CREDITS TO YOUR ACCOUNT 
  
 4.1 Account. For record
keeping purposes only, an Account will be maintained for all persons participating in the Plan. Your Account will be used solely to determine the amounts to be paid to you under the Plan. Your Account will not constitute or be treated as a trust
fund for your benefit. 
  
 4.2 Credits. For each year you are eligible, the
Company will credit your Account with your share of Plan Credits in an amount equal to (i) ten percent (10%), multiplied by (ii) your Compensation for the year that is not recognized under the Retirement Plan either because it is in excess of the
Salary Cap, or deferred under the NQDC, or both. 
  
 4.3 Earnings.
Your Account will be credited with Earnings with respect to the investments of the Plan Credits credited to your Account. Earnings will be credited at the rate declared by the Committee, acting in its sole discretion, after taking into account the

  

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 investment performance of the investment vehicles selected by the Committee, or, if the Committee permits, selected by
you from among the investment vehicles available under the Retirement Plan (excluding the Amgen Inc. Stock Fund). 
  
 4.4 Vesting of Your Account. Your Account will become fully vested upon termination of your employment with the Company on or after (1) your Normal Retirement
Date, (2) the date of your Disability, or (3) your death. If your employment with the Company is terminated for any other reason, your Account will be vested in accordance with the following schedule: 
  

			
	 Years of Service

	 	 Vested Percentage

	 Less than 3
	 	0%
	 3 or more
	 	100%

  
 Notwithstanding the foregoing vesting
schedule, if a portion of your Compensation for a year consists of amounts that were deferred under the NQDC, then a portion of that year’s Plan Credits in an amount equal to (i) 10%, multiplied by (ii) the amount of Compensation deferred under
the NQDC that would have been taken into account under the Retirement Plan if it had not been deferred, shall be immediately vested. 
  
 Any portion of your Account that is not vested on your termination of employment will be permanently forfeited. All Accounts will be subject to the creditors of the
Company in the event of the insolvency of the Company. 
  
 4.5 Determination of
Accounts. Your Account will consist of all your credited Plan Credits and Earnings. 
  
 4.6 Statement of Accounts. Prior to March 1 of each year or at such other time as determined by the Committee, the Committee will distribute statements to you showing the balance of your Account. 
  
 ARTICLE V 
 DISTRIBUTIONS 
  
 5.1 Distributions. Following the termination of your employment with the Company, the Company will pay you the vested balance in your Account. The payment will be made to you in a lump sum cash payment as soon as administratively
practicable following your termination of employment. In the event of your death prior to receiving a distribution of your vested Account balance, the unpaid balance will be paid to your Beneficiary as soon as administratively practicable following
your death. 
  

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 5.2 Withholding Payroll Taxes. The Company will withhold any taxes required to be withheld from payments made from
the Plan to satisfy any federal, state, or local requirements regarding tax withholding. 
  
 5.3 Payments to Incompetents. Whenever and as often as any person entitled to receive a distribution under the Plan shall be under a legal disability or, in the sole judgment of the Committee, shall otherwise
be unable to care for such distributions to the person’s own best interest and advantage, the Committee, in the exercise of its discretion, may direct such distributions to be made in any one or more of the following ways: 
  

	 	(a)	directly to such person; 

  

	 	(b)	to such person’s spouse; 

  

	 	(c)	to such person’s legal guardian or conservator; or 

  

	 	(d)	to any other person to be held and used for such person’s benefit. 

  
 The decision of the Committee shall, in each case, be final and binding upon all parties, and any distribution made pursuant to the power herein conferred on the
Committee shall, to the extent so made, be a complete discharge of the obligations under the Plan of the Company and the Committee with respect to such person. 
  

ARTICLE VI 
 BENEFICIARY
DESIGNATION 
  
 6.1 Beneficiary Designation. Your Beneficiary under
the Plan will be the same Beneficiary you select under the Retirement Plan. If you change your Beneficiary designation under the Retirement Plan, your Beneficiary designation under the Plan will automatically change as well. 
  
 6.2 No Beneficiary Designation. If you fail to designate a Beneficiary under the
Retirement Plan, or if the Beneficiary you designate dies before you or before complete distribution of your benefits, your designated Beneficiary will be the first of the following classes in which there is a survivor: 
  

	 	(a)	your surviving Spouse; 

  

	 	(b)	your children, except if any of the children predecease you but leave surviving issue, then such issue will take by right of representation the share the parent would have taken if
living; 

  

	 	(c)	your estate. 

  

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 6.3 Effect of Payment. The distribution to the Beneficiary completely discharges Company’s obligations under
this Plan. 
  
 ARTICLE VII 
 ADMINISTRATION 
  
 7.1 Committee; Duties. This Plan is administered by the Committee, or its duly appointed delegate or delegates, who may or may not be employees of the Company. The
Committee (or its delegates) has the same duties, discretionary and interpretive authority and rights under this Plan as the Global Benefits Committee, and its appointees and delegates, has under the Retirement Plan; provided, however, nothing in
this Section 7.1 shall be construed to impose any fiduciary duty on the Committee or its delegates under ERISA. The decisions or actions of the Committee with respect to any question arising out of or in connection with the administration,
interpretation or application of the Plan and the rules or regulations promulgated hereunder will be final, conclusive and binding upon all persons having any interest in the Plan. 
  
 7.2 Indemnity of Committee. The Company will indemnify and hold harmless the members of the Committee against any and all claims,
loss, damage, expense or liability arising from any action or failure to act with respect to this Plan, except in the case of the Committee’s gross negligence or willful misconduct. 
  
 7.3 Claims Procedure. The Claims Procedure under the Plan is the same as that under the Retirement Plan, including the arbitration
requirements set forth therein. 
  
 ARTICLE VIII 

AMENDMENT AND TERMINATION OF PLAN 
  
 8.1 Amendment. The Committee may at any time amend the Plan in whole or in part. No amendment may decrease or restrict the amount accrued in any Account maintained
under the Plan through the date of Amendment. 
  
 8.2 Company’s Right to
Terminate. The Board may at any time partially or completely terminate the Plan if, in its judgment, the tax, accounting, or other effects of the continuance of the Plan, or potential payments thereunder, would not be in the best interests of
the Company. 
  

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 ARTICLE IX 
 MISCELLANEOUS 
  
 9.1 Unfunded
Plan. This Plan is intended to be an unfunded plan for tax law purposes and for purposes of Title I of the Employee Retirement Income Act of 1974, as amended (“ERISA”), maintained primarily to provide benefits for a select group of
management or highly compensated employees. This Plan is not intended to create an investment contract, but to provide tax planning opportunities and retirement benefits to eligible individuals who have elected to participate in the Plan. Eligible
individuals are members of management who, by virtue of their position with the Company, are uniquely informed as to the Company’s operations and have the ability to materially affect the Company’s profitability and operations. 

 
 9.2 Unsecured General Creditor. Neither you nor your Beneficiaries, heirs,
successors and assigns will have any legal or equitable rights, interest or claims in any property or assets of the Company, nor will they be Beneficiaries of, or have any rights, claims or interests in any life insurance policies, annuity contracts
or the proceeds therefrom owned or which may be acquired by the Company. Such policies or other assets of the Company will not be held under any trust for your benefit or that of your Beneficiaries, heirs, successors or assigns, or held in any way
as collateral security for the fulfilling of the obligations of the Company under this Plan. Any and all of the Company’s assets and policies will be, and remain, the general, unpledged, unrestricted assets of the Company. The Company’s
obligation under the Plan will be that of an unfunded and unsecured promise of the Company to pay money in the future. 
  
 9.3 Trust Fund. The Company will pay all Plan benefits. At its discretion, the Company may establish one or more trusts, with such trustees as the Board may
approve, for the purpose of providing for the payment of such benefits. Such trust or trusts may be irrevocable, but the assets thereof will be subject to the claims of the Company’s creditors. To the extent any benefits provided under the Plan
are actually paid from any such trust, the Company will have no further obligation with respect thereto, but to the extent not so paid, such benefits will remain the obligation of, and paid by, the Company. 
  
 9.4 Nonassignability. Neither you nor any other person may commute, sell, assign,
transfer, hypothecate or convey in advance of actual receipt the amounts, if any, payable hereunder, or any part thereof, which are expressly declared to be nonassignable and nontransferable. No part of the amounts payable will, prior to actual
payment, be subject to seizure or sequestration for the payment of any debts, judgments, alimony or separate maintenance owed by you or any other person (other than amounts owed to the Company’s creditors in the event of the Company’s
insolvency), nor be transferable by operation of law in the event of the bankruptcy or insolvency of you or any other person (other than the Company). Notwithstanding the above, vested benefits will be payable to an individual other than you under
this Plan in accordance with a court order upon the determination by the Committee that such order (i) has been issued by a court with appropriate jurisdiction (ii) has been properly served on the Company, (iii) is reasonably clear to, and
administrable by, the Committee, (iv) does not require any benefit not otherwise provided under the Plan, and (v) requires payment of a portion of your vested Account to someone other than you. 
  

 7 

 9.5 Not a Contract of Employment. The terms and conditions of this Plan may not be construed to constitute a
contract of employment between you and the Company and you (or your Beneficiary) will have no rights against the Company except as otherwise specifically provided herein. Moreover, nothing in this Plan will be deemed to give you the right to be
retained in the service of the Company as an employee or otherwise, or to interfere with the right of the Company to discipline or discharge you at any time. 
  
 9.6 Cooperation. You are required to cooperate with the Company by furnishing any and all information requested by the Company in order to facilitate the payment
of benefits hereunder. 
  
 9.7 Terms. Whenever words are used in this Plan
in the masculine they will be construed as though they were used in the feminine in all cases where they would so apply; and whenever any words are used in this Plan in the singular or in the plural, they will be construed as though they were used
in the plural or the singular, as the case may be, in all cases where they would so apply. 
  
 9.8 Captions. The captions of the articles, sections and paragraphs of this Plan are for convenience only and do not control or affect the meaning or construction of any of its provisions. 
  
 9.9 Governing Law. The provisions of this Plan are to be construed and interpreted
according to the laws of the State of California to the extent that they have not been preempted by federal law. 
  
 9.10 Validity. In case any provision of this Plan is found to be held illegal or invalid for any reason, said illegality or invalidity will not affect the
remaining parts hereof, but this 
  
 [Remainder of this page
intentionally left blank] 
  

 8 

 IN WITNESS WHEREOF, the Company has signed this amended and restated Plan document as of October 7, 2004.

  

			
	 “Company”

	
	 Amgen Inc., a Delaware corporation

		
	 By:
	 	 /s/ BRIAN MCNAMEE

	 Title:
	 	  
 Senior Vice President, Human
Resources

  

 9 

 APPENDIX A 
  
 Participating Subsidiaries and Affiliates of Amgen Inc. 
  

	1.	Amgen USA Inc. – January 1, 2002 

	2.	Immunex Corporation – January 1, 2003 

	3.	Immunex Manufacturing Corporation - January 1, 2003 

	4.	Immunex Rhode Island Corporation - January 1, 2003 

	5.	Amgen Worldwide Services, Inc. – January 1, 2004 

	6.	Amgen San Francisco, LLC - January 1, 2005 

	7.	Tularik Pharmaceutical Company – January 1, 2005 

  

 10

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