Document:

EXHIBIT 4.4

                  GENETIC VECTORS, INC. 1999 STOCK OPTION PLAN

                                   ARTICLE I.

                        PURPOSE AND ADOPTION OF THE PLAN

      1.1.  Purpose. The purpose of the Genetic Vectors,  Inc. 1999 Stock Option
Plan  (hereinafter  referred  to as the  "Plan")  is to assist  the  Company  in
attracting and retaining highly  competent  employees and to act as an incentive
in  motivating  selected  officers and other key  employees of the Company,  and
directors  and  consultants  of the  Company,  to  achieve  long-term  corporate
objectives.

      1.2.  Adoption  and  Term.  The  Plan has been  approved  by the  Board of
Directors of Genetic Vectors, Inc., to be effective as of December 31, 1999 (the
"Effective  Date");  provided,  however,  that no Incentive  Stock Option may be
granted   hereunder  unless  and  until  the  Plan  has  been  approved  by  the
shareholders  of the Company  within 12 months before or after the date the Plan
is adopted by the Board.  The Plan shall  remain in effect until  terminated  by
action of the Board; provided,  however, that no Option may be granted hereunder
after the tenth anniversary of the Effective Date.

                                   ARTICLE II.

                                   DEFINITIONS

      For the purpose of this Plan, the following  capitalized  terms shall have
the following meanings:

      2.1   "Beneficiary" means an individual,  trust or estate who or which, by
a written  designation of the Participant filed with the Company or by operation
of law, succeeds to the rights and obligations of the Participant under the Plan
and the Option Agreement upon the Participant's death.

      2.2   "Board" means the Board of Directors of the Company.

      2.3   "Change in Control" means, and shall be deemed to have occurred upon
the occurrence of, any one of the following events:

            a) The acquisition in one or more transactions,  other than from the
Company,  by any  individual,  entity or group  (within  the  meaning of Section
13(d)(3) or 14(d)(2) of the Exchange  Act) of beneficial  ownership  (within the
meaning of Rule 13d-3 promulgated under the Exchange Act) of a number of Company
Voting  Securities in excess of 15% of the Company Voting Securities unless such
acquisition has been approved by the Board;

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            b) Any  election  of persons to the Board that  causes a majority of
the Board to consist of persons  other than (i) persons who were  members of the
Board on the Effective  Date and (ii) persons who were nominated for election as
members of the Board at a time when a majority of the Board consisted of persons
who were members of the Board on the Effective Date; provided, however, that any
person nominated for election by a Board at least a majority of whom constituted
persons  described in clauses (i) and/or (ii) or by persons who were  themselves
nominated  by such  Board  shall,  for this  purpose,  be  deemed  to have  been
nominated by a Board composed of persons described in clause (i);

            c) Approval by the shareholders of the Company of a  reorganization,
merger  or  consolidation,  unless,  following  such  reorganization,  merger or
consolidation, all or substantially all of the individuals and entities who were
the respective  beneficial  owners of the  Outstanding  Common Stock and Company
Voting  Securities   immediately  prior  to  such   reorganization,   merger  or
consolidation,   following   such   reorganization,   merger  or   consolidation
beneficially own, directly or indirectly,  more than 80% of,  respectively,  the
then  outstanding  shares of common stock and the  combined  voting power of the
then outstanding voting securities entitled to vote generally in the election of
directors or  trustees,  as the case may be, of the entity  resulting  from such
reorganization,  merger or consolidation in substantially the same proportion as
their  ownership of the Outstanding  Common Stock and Company Voting  Securities
immediately prior to such reorganization,  merger or consolidation,  as the case
may be; or

            d) Approval  by the  shareholders  of the  Company of (i) a complete
liquidation or dissolution of the Company or (ii) a sale or other disposition of
all or substantially all the assets of the Company.

      2.4.  "Code"  means  the  Internal  Revenue  Code  of  1986,  as  amended.
References  to a  section  of the  Code  shall  include  that  section  and  any
comparable   section  or  sections  of  any  future   legislation  that  amends,
supplements or supersedes said section

      2.5.  "Committee" means the Committee defined in Section 3.1.

      2.6.  "Common  Stock" means  Common Stock of the Company,  par value $.001
per share.

      2.7.  "Company" means Genetic Vectors,  Inc., a Florida  corporation,  and
its successors.

      2.8.  "Company Voting  Securities"  means the combined voting power of the
Common Stock of the Company and all other outstanding  securities of the Company
entitled to vote generally in the election of directors of the Company.

      2.9.  "Date of Grant" means the date  designated  by the  Committee as the
date as of which it grants an Option,  which shall not be earlier  than the date
on which the Committee approves the granting of such Option.

      2.10. "Exchange  Act"  means  the  Securities  Exchange  Act of  1934,  as
amended.

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      2.11. "Fair Market Value" means,  as of any  applicable  date:  (i) if the
Common Stock is listed on a national  securities  exchange or is authorized  for
quotation on The Nasdaq  National  Market  System  ("NMS"),  the closing  price,
regular way, of the Common Stock on such exchange or NMS, as the case may be, on
such date or if no sale of the Common Stock shall have occurred on such date, on
the next  preceding date on which there was such a reported sale; or (ii) if the
Common  Stock is not listed for  trading on a national  securities  exchange  or
authorized for quotation on NMS, the closing bid price as reported by The Nasdaq
SmallCap  Market on such date,  or if no such price shall have been reported for
such date, on the next preceding  date for which such price was so reported;  or
(iii) if the Common  Stock is not listed  for  trading on a national  securities
exchange or authorized  for quotation on NMS or The Nasdaq  SmallCap  Market (if
applicable),  the last  reported  bid price  published  in the "pink  sheets" or
displaced on the National  Association  of  Securities  Dealers,  Inc.  ("NASD")
Over-the-Counter Bulletin Board, as the case may be; or (iv) if the Common Stock
is not listed for trading on a national securities  exchange,  is not authorized
for quotation on NMS or The Nasdaq  SmallCap  Market and is not published in the
"pink  sheets" or  displayed on the NASD  Electronic  Bulletin  Board,  the fair
market value of the Common Stock as  determined  in good faith under  procedures
established by the Board which  determination  shall be final and binding on all
Participants.

      2.12. "Incentive  Stock Option" means a stock option within the meaning of
Section 422 of the Code.

      2.13. "Merger"  means any  merger,  reorganization,  consolidation,  share
exchange,  transfer  of  assets  or  other  transaction  having  similar  effect
involving the Company.

      2.14. "Nonstatutory  Stock  Option"  means a stock  option which is not an
Incentive Stock Option.

      2.15. "Option Agreement" means a written agreement between the Company and
a Participant  specifically  setting forth the terms and conditions of an Option
granted under the Plan.

      2.16. "Option Price", with respect to Options,  shall have the meaning set
forth in Section 6.1(b).

      2.17. "Option Term" means,  with respect to an Option,  the period of time
set forth in the Option Agreement during which the Option may be exercised.

      2.18. "Options" means all  Nonstatutory  Stock Options and Incentive Stock
Options granted at any time under the Plan.

      2.19. "Outstanding  Common  Stock"  means,  at any time,  the  issued  and
outstanding shares of Common Stock.

      2.20. "Participant"  means a person  designated to receive an Option under
the Plan in accordance with Section 5.1.

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      2.21  "Plan"  means the Genetic  Vector,  Inc.  1999 Stock  Option Plan as
described herein, as the same may be amended from time to time.

      2.22. "Subsidiary" means a subsidiary of the Company within the meaning of
Section 424(f) of the Code.

      2.23. "Ten Percent  Shareholder" means any individual who, at the time the
Option is granted,  owns stock  possessing  more than ten  percent  (10%) of the
total combined voting power of all classes of stock of the Company.

                                  ARTICLE III.

                                 ADMINISTRATION

      3.1.  Committee.  The Plan shall be  administered  by the Board or, in the
discretion  of the  Board,  by the  Compensation  Committee  of the  Board  (the
"Committee") comprised of one or more persons. The Committee or Board shall have
exclusive and final  authority in each  determination,  interpretation  or other
action  affecting the Plan and its  Participants.  The Board or Committee  shall
have the sole  discretionary  authority to interpret  the Plan, to establish and
modify  administrative  rules  for the  Plan,  to  impose  such  conditions  and
restrictions on Options as it determines appropriate,  and to take such steps in
connection with the Plan and Options granted  hereunder as it may deem necessary
or  advisable.  The Board or  Committee  may  delegate  such of its  powers  and
authority  under the Plan as it deems  appropriate  to  designated  officers  or
employees  of the  Company.  In the event of such  delegation  of  authority  or
exercise of authority by the Board or  Committee,  references in the Plan to the
Committee  shall  be  deemed  to  refer  to the  delegate  of the  Board  or the
Committee,  as the case may be. For  purposes  of this Plan,  references  to the
Committee  shall be deemed  references to the Board to the extent that the Board
has not appointed a Committee to administer the Plan.

                                   ARTICLE IV.

                                     SHARES

      4.1.  Number of Shares  Issuable.  The maximum number of shares  initially
authorized to be issued under the Plan shall be four hundred thousand  (400,000)
shares of Common Stock.  The number of shares  available for issuance  under the
Plan shall be further  subject to adjustment in accordance with Section 7.6. The
shares to be offered  under the Plan shall be  authorized  and  unissued  Common
Stock, or issued Common Stock which shall have been reacquired by the Company.

      4.2.  Shares  Subject to Terminated  Options.  Common Stock covered by any
unexercised  portions of terminated Options (including canceled Options) granted
under  Article VI and Common Stock  subject to any Options  which are  otherwise
surrendered  by the  Participant  may again be subject to new Options  under the
Plan.

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                                   ARTICLE V.

                                  PARTICIPATION

      5.1  Eligible  Participants.  Participants  in  the  Plan  shall  be  such
officers,  key  employees,  directors  and  consultants  of the  Company  as the
Committee,  in its  sole  discretion,  may  designate  from  time to  time.  The
Committee's  designation  of a  Participant  in any year shall not  require  the
Committee  to  designate  such person to receive  Options or grants in any other
year.  The  Committee  shall  consider  such  factors as it deems  pertinent  in
selecting  Participants  and  in  determining  the  type  and  amount  of  their
respective Options.

                                   ARTICLE VI.

                                  STOCK OPTIONS

      6.1.  Option Awards.

            a)  General.  The Committee may grant, to such  Participants  as the
Committee may select,  Options  entitling the  Participant to purchase shares of
Common Stock from the Company in such number,  at such price,  and on such terms
and subject to such conditions, not inconsistent with the terms of this Plan, as
may be established by the Committee.  The terms of any Option granted under this
Plan shall be set forth in an Option Agreement.

            b)  Purchase  Price of  Options.  The Option  Price of each share of
Common Stock which may be purchased  upon  exercise of any Option  granted under
the Plan shall be determined by the Committee;  provided, however, that (i) with
respect to  Incentive  Stock  Options,  the Option  Price per share shall in all
cases be equal to or  greater  than the Fair  Market  Value of a share of Common
Stock on the Date of Grant as required  under Section 422 of the Code,  and (ii)
with  respect  to  any  Incentive  Stock  Option  granted  to  any  Ten  Percent
Shareholder,  the  Option  Price  per  share  shall in all  cases be equal to or
greater  than 110 percent of the Fair Market Value of a share of Common Stock on
the Date of Grant as required under Section 422 of the Code.

            c)  Designation of Options.  Except as otherwise  expressly provided
in the  Plan,  the  Committee  may  designate,  at the time of the grant of each
Option, the Option as an Incentive Stock Option or a Nonstatutory Stock Option.

            d)  Incentive Stock Option Share  Limitation.  No Participant may be
granted  Incentive  Stock  Options  under  the Plan (or any  other  plans of the
Company)  which would  result in shares  with an  aggregate  Fair  Market  Value
(measured on the Date of Grant) of more than $100,000 first becoming exercisable
in any one calendar year.

            e)  Rights as a  Shareholder.  A  Participant  or a transferee of an
Option  pursuant  to  Section  7.4 shall  have no rights as a  shareholder  with
respect to Common Stock covered by an Option until the Participant or transferee
shall have  become the holder of record of any such  shares,  and no  adjustment
shall be made for dividends in cash or other property or  distributions or other
rights with  respect to any such Common Stock for which the record date is prior
to the date on which the  Participant  or a transferee  of the Option shall have
become the holder of record of any such shares covered by the Option;  provided,
however,  that Participants are entitled to share adjustments to reflect capital
changes under Section 7.6.

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      6.2.  Terms of Stock Options.

            a)  Conditions  on  Exercise.  An Option  Agreement  with respect to
Options may contain such waiting  periods,  exercise dates and  restrictions  on
exercise  (including,  but not  limited  to,  periodic  installments)  as may be
determined by the Committee as of the Date of Grant.

            b)  Duration of Options.  Options shall terminate after the first to
occur of the following events:

                (i)   Expiration  of  the  Option  as  provided  in  the  Option
Agreement;

                (ii)  Termination  of the Option as  provided  in  Section  6.3,
following the Participant's termination of employment; or

                (iii) Ten years from the Date of Grant (five years from the Date
of Grant in the case of any  Incentive  Stock  Option  granted to a Ten  Percent
Shareholder).

            c)  Acceleration  of  Exercise  Time.  The  Committee,  in its  sole
discretion,  shall  have the right  (but  shall  not in any case be  obligated),
exercisable  at any time after the Date of Grant,  to permit the exercise of any
Option prior to the time such Option would otherwise  become  exercisable  under
the terms of the Option Agreement.

            d)  Extension  of  Exercise  Time.   The  Committee,   in  its  sole
discretion,  shall  have the right  (but  shall  not in any case be  obligated),
exercisable  on or at any time  after the Date of Grant,  to permit  any  Option
granted  under this Plan to be exercised  after its  expiration  date,  subject,
however, to the limitation described in Section 6.2(b)(iii).

      6.3.  Exercise of Options upon Termination of Employment.

            a)  General.  In  event  of the  termination  of  employment  of the
Participant by the  Participant or the Company for any reason  whatsoever  other
than death or Permanent Disability (as defined in Section 6.3(b)), any vested or
nonvested Options which are not exercised (or exercisable)  prior to the date of
such  termination  of employment  shall  terminate on such date and shall not be
exercisable  at  any  time  thereafter.   For  purposes  of  this  Section  6.3,
termination  of employment  with respect to a  Participant  who is a director or
consultant  and who is not  otherwise  an  employee  of the  Company  shall mean
voluntary  or  involuntary  termination  of  Board  service  or  the  consulting
relationship, as the case may be, for any reason.

            b)  Death or Complete Disability. In the event of the termination of
the employment of the  Participant  by reason of death or Permanent  Disability,
any Options  that were vested prior to the date of such  termination  (and which
were not previously  exercised),  together with any other Options  designated in
writing by the  Committee,  shall  terminate  on the earliest of (i) one hundred
eighty  days  after  the date of such  termination,  or (ii) the last day of the
Option  Term.  Any  Options  that  were  not  vested  prior  to the date of such
termination  and do not become  vested  pursuant  to the  immediately  preceding
sentence  shall  terminate as of the date of such  termination  and shall not be
exercisable  at any time  thereafter.  As used in this Plan,  the term "Complete

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Disability" means the inability of the Participant,  due to illness, accident or
any other physical or mental  incapacity,  to perform  services on behalf of the
Company  for an  aggregate  of sixty (60) days  within any period of twelve (12)
consecutive months during the term hereof.

      6.4.  Exercise  Procedures.  Each Option  granted  under the Plan shall be
exercised by written notice to the Company which must be received by the officer
or employee of the Company  designated in the Option  Agreement on or before the
close of business on the  expiration  date of the  Option.  The Option  Price of
shares purchased upon exercise of an Option granted under the Plan shall be paid
in full in cash by the Participant  pursuant to the Option Agreement;  provided,
however, that the Committee may (but shall not be required to) permit payment to
be made by delivery to the Company of either (a) Common Stock (which may include
shares otherwise issuable in connection with the exercise of the Option, subject
to such rules as the Committee deems  appropriate),  (b) any combination of cash
and Common  Stock,  (c) by the delivery to the Company by the  Participant  of a
full  recourse  promissory  note  containing  such  terms as the  Committee  may
determine,  or (d) such other  consideration as the Committee deems appropriate.
In the event  that any  Common  Stock  shall be  transferred  to the  Company to
satisfy  all or any part of the Option  Price,  the part of the  Purchase  Price
deemed to have been satisfied by such transfer of Common Stock shall be equal to
the product  derived by  multiplying  the Fair Market Value of a share of Common
Stock as of the date of  exercise  times the  number  of shares of Common  Stock
transferred to the Company.  The  Participant may not transfer to the Company in
satisfaction of the Option Price any fractional  share of Common Stock. Any part
of the Option  Price paid in cash upon the exercise of any Option shall be added
to the general  funds of the  Company  and may be used for any proper  corporate
purpose.  Unless the  Committee  shall  otherwise  determine,  any Common  Stock
transferred  to the  Company as payment of all or part of the Option  Price upon
the exercise of any Option shall be held as treasury shares.

      6.5.  Change in Control. Unless otherwise provided by the Committee in the
applicable  Option Agreement,  in the event of a Change in Control,  all Options
outstanding  on the date of such  Change in  Control  that  have not  previously
vested or terminated  under the terms of the applicable  Option  Agreement shall
become  immediately  and fully  exercisable.  The provisions of this Section 6.5
shall not be applicable to any Options granted to a Participant if any Change in
Control results from such Participant's beneficial ownership (within the meaning
of rule 13d-3 under the Exchange Act) of Company Voting Securities.

                                  ARTICLE VII.

                                  MISCELLANEOUS

      7.1   Plan Provisions Control  Option  Terms.  The terms of the Plan shall
govern all Options  granted under the Plan,  and in no event shall the Committee
have the power to grant any Option  under the Plan which is  contrary  to any of
the  provisions of the Plan.  In the event any provision of any Options  granted
under the Plan shall  conflict with any term in the Plan as  constituted  on the
Date of Grant of such Option, the term in the Plan as constituted on the Date of
Grant of such  Option  shall  control.  Except as  provided  in Section  7.3 and
Section 7.6, the terms of any Option  granted  under the Plan may not be changed
after the Date of Grant of such Option so as to materially decrease the value of
the Option without the express written approval of the holder.

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      7.2.  Option  Agreement.  No person shall have any rights under any Option
granted under the Plan unless and until the Company and the  Participant to whom
such Option shall have been granted  shall have executed and delivered an Option
Agreement  or  received  any  other  Option  acknowledgment  authorized  by  the
Committee expressly granting the Option to such person and containing provisions
setting forth the terms of the Option.

      7.3.  Modification of Option After Grant. No Option granted under the Plan
to a Participant may be modified (unless such  modification  does not materially
decrease  the value of the  Option)  after the Date of Grant  except by  express
written  agreement  between the Company and the  Participant,  provided that any
such change (a) shall not be  inconsistent  with the terms of the Plan,  and (b)
shall be approved by the Committee.

      7.4. Limitation on Transfer. A Participant's rights and interest under the
Plan  may not be  assigned  or  transferred  other  than by will or the  laws of
descent and  distribution,  and during the lifetime of a  Participant,  only the
Participant  personally  (or  the  Participant's  personal  representative)  may
exercise rights under the Plan. The  Participant's  Beneficiary may exercise the
Participant's rights to the extent they are exercisable under the Plan following
the death of the Participant.

      7.5.  Taxes.  The Company  shall be entitled,  if the  Committee  deems it
necessary or desirable,  to withhold (or secure payment from the  Participant in
lieu of withholding)  the amount of any withholding or other tax required by law
to be withheld or paid by the Company with respect to any amount  payable and/or
shares issuable with respect to such  Participant's  Option,  or with respect to
any  income  recognized  upon a  disqualifying  disposition  of shares  received
pursuant to the exercise of an Incentive Stock Option, and the Company may defer
payment or issuance of shares upon exercise of an Option unless  indemnified  to
its  satisfaction  against any  liability  for any such tax.  The amount of such
withholding  or tax payment  shall be  determined  by the Committee and shall be
payable  by the  Participant  at such  time  as the  Committee  determines.  The
Participant  shall meet his or her withholding  requirement by direct payment to
the  Company in cash of the amount of any taxes  required  to be  withheld  with
respect to such Option; provided, however, that the Committee may (but shall not
be  required  to)  permit  the  Participant  to  meet  his  or  her  withholding
requirement by (i) having withheld from such Option at the appropriate time that
number of shares of Common Stock, rounded up to the next whole share, whose Fair
Market  Value  is  equal to the  amount  of  withholding  taxes  due,  or (ii) a
combination of shares and cash.

      7.6.  Adjustments to Reflect Capital Changes.

            a)  Recapitalization.  The  number  and kind of  shares  subject  to
outstanding  Options,  the Option Price for such shares,  the number and kind of
shares available for Options subsequently granted under the Plan and the maximum
number of shares in respect of which Options can be made to any  Participant  in
any calendar year shall be appropriately adjusted to reflect any stock dividend,
stock split,  combination or exchange of shares, merger,  consolidation or other

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change in capitalization  with a similar substantive effect upon the Plan or the
Options  granted  under the Plan.  The  Committee  shall have the power and sole
discretion to determine the amount of the adjustment to be made in each case.

            b)  Merger.  After any Merger in which the Company is the  surviving
corporation, each Participant shall, at no additional cost, be entitled upon any
exercise of an Option or receipt of another  Option to  receive,  subject to any
required action by shareholders, in lieu of the number of shares of Common Stock
receivable  or  exercisable  pursuant  to such  Option,  the number and class of
shares or other  securities to which such  Participant  would have been entitled
pursuant  to the  terms  of the  Merger  if,  at the  time of the  Merger,  such
Participant  had been the  holder of  record of a number of shares  equal to the
number of shares receivable or exercisable  pursuant to such Option.  Comparable
rights shall accrue to each  Participant  in the event of successive  Mergers of
the character  described above. In the event of a Merger in which the Company is
not  the  surviving  corporation,  the  surviving,  continuing,   successor,  or
purchasing corporation, as the case may be (the "Acquiring Corporation"),  shall
either assume the Company's  rights and  obligations  under  outstanding  Option
Agreements or substitute awards in respect of the Acquiring  Corporation's stock
for such outstanding Options. In the event the Acquiring  Corporation elects not
to assume or substitute for such  outstanding  Options,  the Board shall provide
that any unexercisable  and/or unvested portion of the outstanding Options shall
be  immediately  exercisable  and  vested as of a date  prior to such  merger or
consolidation,  as the Board so determines.  The exercise  and/or vesting of any
Option that was  permissible  solely by reason of this  Section  7.6(b) shall be
conditioned  upon the consummation of the merger or  consolidation.  Any Options
which are neither  assumed by the Acquiring  Corporation nor exercised as of the
date of the Merger shall  terminate  effective as of the  effective  date of the
Merger.

            c)  Options to Purchase Shares of Stock of Acquired Companies. After
any  merger  in  which  the  Company  or  a  Subsidiary  shall  be  a  surviving
corporation, the Committee may grant substituted options under the provisions of
the Plan,  pursuant to Section 424 of the Code,  replacing  old options  granted
under a plan of another party to the merger whose shares of stock subject to the
old  options  may no  longer be  issued  following  the  merger.  The  foregoing
adjustments  and manner of  application  of the  foregoing  provisions  shall be
determined by the Committee in its sole  discretion.  Any such  adjustments  may
provide for the  elimination  of any  fractional  shares  which might  otherwise
become subject to any Options.

      7.7.  No Right to  Employment.  No employee or other person shall have any
claim of right to be granted an Option under this Plan. Neither the Plan nor any
action taken hereunder shall be construed as giving any employee any right to be
retained in the employ of the Company.

      7.8.  Options Not Includable for Benefit  Purposes.  Common Stock received
by a Participant pursuant to the provisions of the Plan shall not be included in
the  determination  of benefits  under any  pension,  group  insurance  or other
benefit plan applicable to the  Participant  which is maintained by the Company,
except as may be  provided  under the terms of such plans or  determined  by the
Board.

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      7.9.  Governing Law. All determinations made and actions taken pursuant to
the Plan shall be governed by the laws of the State of Florida and  construed in
accordance therewith.

      7.10. No  Strict  Construction.  No rule of strict  construction  shall be
implied against the Company,  the Board,  the Committee,  or any other person in
the interpretation of any of the terms of the Plan, any Option granted under the
Plan or any rule or procedure established by the Committee.

      7.11. Captions. The captions (i.e., all Section headings) used in the Plan
are for convenience only, do not constitute a part of the Plan, and shall not be
deemed to limit,  characterize  or affect in any way any provisions of the Plan,
and all  provisions  of the Plan shall be construed as if no captions  have been
used in the Plan.

      7.12.  Severability.  Whenever  possible,  each  provision in the Plan and
every Option at any time  granted  under the Plan shall be  interpreted  in such
manner as to be effective and valid under  applicable  law, but if any provision
of the Plan or any Option at any time granted under the Plan shall be held to be
prohibited by or invalid under  applicable law, then (a) such provision shall be
deemed  amended to  accomplish  the  objectives  of the  provision as originally
written to the fullest extent  permitted by law and (b) all other  provisions of
the Plan and every other Option at any time granted  under the Plan shall remain
in full force and effect.

      7.13. Amendment and Termination.

            a) Amendment.  The Board shall have complete  power and authority to
amend the Plan at any time. No termination or amendment of the Plan may, without
the consent of the  Participant to whom any Option shall  theretofore  have been
granted under the Plan, adversely affect the right of such individual under such
Option.

            b)  Termination.  The  Board  shall  have the right and the power to
terminate  the Plan at any time. No Option shall be granted under the Plan after
the  termination of the Plan, but the termination of the Plan shall not have any
other effect and any Option  outstanding  at the time of the  termination of the
Plan may be  exercised  after  termination  of the Plan at any time prior to the
expiration  date of such Option to the same  extent such Option  would have been
exercisable had the Plan not terminated.

                                      * * *EXHIBIT 10.28

                         EXECUTIVE EMPLOYMENT AGREEMENT

      THIS EXECUTIVE  EMPLOYMENT  AGREEMENT  ("AGREEMENT") is made as of January
17, 2000 by and between GENETIC VECTORS,  INC., a Florida corporation,  with its
principal executive offices at 5201 N.W. 77th Avenue,  Suite 100, Miami, Florida
33166 (the "COMPANY") and JEROME STREIFEL, an individual residing at the address
set forth in Section 13 hereof (the "EXECUTIVE").

      WHEREAS,  the Executive has been offered the position of Vice President of
Operations  ("VICE  PRESIDENT")  of the  Company and will begin to serve in such
capacities on the Effective Date (as herein defined);

      WHEREAS,  the  Company  wishes to assure  itself  of the  services  of the
Executive  for the period  provided  for herein and the  Executive is willing to
serve in the employ of the Company for said period upon the terms and conditions
hereinafter provided; and

      WHEREAS, the Company's Board has determined that the best interests of the
Company  and its  shareholders  would be served by  providing  for the terms and
conditions of the Executive's employment as set forth herein.

      NOW, THEREFORE,  in consideration of the mutual covenants herein contained
and intending to be legally bound hereby,  the Company and the Executive  hereby
agree as follows:

      Section 1. DEFINITIONS. As used herein, the following terms shall have the
meanings set forth below.

      "DISABILITY"  of the Executive  means that, as a result of the Executive's
incapacity  due to physical or mental  illness,  the  Executive  shall have been
absent  from his duties on a full time  basis for thirty  (30) days in any three
(3) month  period.  If the  Executive is prevented  from  performing  his duties
because of Disability,  upon request by the Company,  the Executive shall submit
to an  examination  by a physician  selected by the  Company,  at the  Company's
expense,  and the  Executive  shall also  authorize  his  personal  physician to
disclose to the selected physician all of the Executive's medical records.

      "FISCAL YEAR" means any fiscal year of the Company, as applicable.

      "PERSON" means any  individual,  sole  proprietorship,  general or limited
partnership,  joint venture, trust,  unincorporated  organization,  association,
corporation, institution, entity, party, limited liability company or government
(whether  territorial,  national,  federal,  state,  provincial,  county,  city,
municipal or otherwise,  including,  without  limitation,  any  instrumentality,
division, agency, body or department thereof).

      Section 2.  EMPLOYMENT AND TERM. The Company hereby employs the Executive,
and the  Executive  hereby  accepts  such  employment  by the  Company,  for the
purposes  and upon the terms and  conditions  contained  in this  Agreement  and

<PAGE>

subject to the  approval of the  Company's  Board of  Directors.  Subject to the
terms and  conditions  contained  herein  and the  approval  of the Board  ("the
"BOARD"), the initial term of this Agreement shall be for a two (2) year period,
commencing on the date on which  Executive  begins his employment at the Company
(the  "EFFECTIVE  DATE"),  and  terminating  on the  second  anniversary  of the
Effective  Date.  Thereafter,  the Company  shall have the  option,  in its sole
discretion to renew this Agreement on its then-current  terms and conditions for
subsequent  one (1) year  extension  terms upon written notice ninety (90) days'
prior to the then applicable term or extension term. The initial term hereof and
any extension term are referred to herein as the "EMPLOYMENT PERIOD."

      Section 3. EMPLOYMENT CAPACITY AND DUTIES. The Executive shall be employed
throughout  the  Employment  Period as the Vice  President of  Operations of the
Company.  The  Executive  shall have the duties  and  responsibilities  normally
associated  and incumbent  with the position of Vice  President of Operations of
the Company and shall  render  services to the Company as its Vice  President of
Operations  and in  connection  therewith  shall  perform  such  duties,  as the
Executive  may  reasonably  be  directed  to  perform  by the CEO and the Board.
Accordingly,  and not by way of  limitation,  as Vice President of Operations of
the  Company,  the  Executive at the request of the Chairman of the Board attend
all meetings of the shareholders of the Company or the Board and, subject to the
direction  or approval of the Board,  the  Executive  shall be  responsible  for
production  and  development  of the Company's  scientific  products,  including
product validation.  In addition,  he will participate in the Company's research
and development projects by providing certain scientific skills as needed.

      Section 4.  EXECUTIVE  PERFORMANCE  COVENANTS.  The Executive  accepts the
employment  described  in Section 3 herein and agrees to devote his full working
time and efforts (except for absences due to illness and appropriate  vacations)
to the business and affairs of the Company and the  performance of the aforesaid
duties and responsibilities as set forth in Section 3.

      Section  5.  SALARY  AND  BONUS.  The  Executive  shall  be paid a  salary
("SALARY") for the period  commencing on the Effective Date at an annual rate of
One Hundred Thousand ($100,000) payable in equal installments in accordance with
the  Company's  payroll  policies.  The Salary shall be pro-rated for any Fiscal
Year  hereunder  which is less than a full Fiscal Year.  The Executive  shall be
entitled to such bonuses as are determined by the Board of Directors.

      Section 6.  REIMBURSEMENT  OF EXPENSES.  The Company  shall  reimburse the
Executive for expenses incurred in providing  services to the Company,  upon the
Executive's submission of appropriate  documentation evidencing such expenses in
accordance with the Company's  reimbursement policies as determined from time to
time by the Board. If there is a dispute as to the eligibility of an expense for
reimbursement in accordance with the Company's reimbursement policies, then such
expense shall be determined to be  reimbursable if approved by a majority of the
Board.

      Section 7. EMPLOYEE BENEFITS,  VACATIONS. During the Employment Period, in
addition to any and all  compensation  and benefits  required or permitted to be

                                       2
<PAGE>

made by the Company to Executive  hereunder,  the  Executive  shall  receive the
benefits and enjoy the perquisites described below:

            a) VACATION.  The Executive shall be entitled to four (4) weeks paid
vacation per annum. Such vacation shall be taken at such times as are consistent
with the needs and policies of the Company; and

            b)  PARTICIPATION  IN BENEFIT PLANS. The Executive shall be entitled
to participate in any group hospitalization,  health, life or other insurance or
death benefit plan, travel or accident  insurance,  restricted or stock purchase
plan,  stock option plan,  retirement  income or pension  plan,  401(k) plan, or
other  present or future group  employee  benefit plan or program of the Company
for which  executives are or shall become  eligible.  Nothing  contained in this
Agreement  shall prevent the Board from amending or otherwise  altering any such
plan, program or arrangement during the Employment Period; and

            c)   INDEMNIFICATION.   The   Executive   shall   be   entitled   to
indemnification and protection from liability as set forth in Section 11.

      Section 8. TERMINATION OF EMPLOYMENT.

            a) NOTICE OF TERMINATION; EMPLOYMENT TERMINATION DATE.

                  (1)  Any  termination  of the  Executive's  employment  by the
Company or the Executive  shall be communicated by written Notice of Termination
to the other  party  hereto.  For  purposes  of this  Agreement,  a  "NOTICE  OF
TERMINATION"  shall mean a notice  which shall  indicate  the  provision in this
Agreement relied upon.

                  (2) "EMPLOYMENT TERMINATION DATE" shall mean the date on which
the  Employment  Period  and the  Executive's  right and  obligation  to perform
employment  services for the Company shall terminate effective upon the first to
occur of the following:

                        (i) If the  Executive's  employment  is  terminated  for
Disability, the date on which the Notice of Termination is given;

                        (ii) If the  Executive's  employment  is  terminated  by
voluntary  action of the Executive (see Section 8(e)), the date specified in the
Notice of Termination,  which date shall be no more than fifteen (15) days after
the date that the Notice of Termination is given;

                        (iii) The death of the Executive;

                        (iv) The expiration of the Employment Period;

                        (v) If the  Executive's  employment is terminated by the
Company  for  Cause  (see  Section  8(b)(1)),  the  date on  which a  Notice  of
Termination is given; and

                                       3
<PAGE>

                        (vi) If the Executive's  employment is terminated by the
Company  other than for Cause,  Disability or death of the  Executive,  the date
specified in the Notice of Termination  which date shall not be more than thirty
(30) days after the date that the Notice of Termination is given.

            b)  TERMINATION FOR CAUSE:

                  (1) The  Company  may  terminate  the  Executive's  employment
hereunder  and  the  Employment  Period  for  Cause.  For the  purposes  of this
Agreement,  "CAUSE"  shall  mean  termination  because of  Executive's  personal
dishonesty,  willful  misconduct,  breach of fiduciary duty  involving  personal
profit, failure to perform stated duties (after written notice and ten (10) days
to cure),  conviction of a violation of any law, rule or regulation  (other than
traffic violations or similar offenses) or breach of any other provision of this
Agreement (after written notice and ten (10) days to cure).

                  (2) If the  Executive's  employment  shall be  terminated  for
Cause,  the  Company  shall pay the  Executive  his unpaid  Salary  through  the
Employment Termination Date.

            c)  TERMINATION  FOR  DISABILITY.  The  Company  may  terminate  the
Executive's employment because of the Disability of the Executive and thereafter
the Company  shall pay to the Executive  (or his  successors)  his unpaid Salary
through the Employment Termination Date.

            d)  TERMINATION  UPON  EXECUTIVE'S   DEATH.  In  the  event  of  the
Executive's  death,  the Company shall pay to the Executive's  estate any unpaid
amount of Salary through the date of death.

            e) VOLUNTARY  TERMINATION BY EXECUTIVE.  In the event that Executive
voluntarily  terminates his employment  with the Company prior to the expiration
of the Employment  Period, the Company shall pay the Executive his unpaid Salary
through the Employment Termination Date.

            f) COMPENSATION UPON TERMINATION OTHER THAN FOR CAUSE.

                  (1) If the Company shall terminate the Executive's  employment
for any reason  other than  pursuant  to  Sections  8(b),  (c) or (d),  then the
Company  shall,  pay to the Executive his unpaid Salary through the remainder of
the  applicable  term or  extension  term as the case may be and any accrued but
unpaid bonus previously  awarded by the Board of Directors at the same time such
Salary or bonus would have been paid had the Executive not been terminated.

      Section 9. STOCK  OPTIONS.  The Company  shall  provide to  the  Executive
pursuant to the terms and  conditions  of the Stock  Options  Addendum  attached
hereto,  stock options (the "STOCK OPTIONS") to acquire Sixty Thousand  (60,000)
common shares of the Company's  capital stock  ("COMMON  SHARES") at an exercise
price equal to the closing price of the Common Shares on the date of grant.

                                       4
<PAGE>

<TABLE>
<CAPTION>
    PERCENTAGE OF STOCK OPTIONS VESTING                           VESTING DATE

                   <S>                                <C>
                   33.3%                                  One year after Effective Date

                   66.6%                               Two years after the Effective Date

                   100%                               Three years after the Effective Date
</TABLE>

      The Stock Options shall be granted under and shall be subject to the terms
and  conditions of the Stock Option  Addendum and the  provisions  thereof shall
control in the event of the termination of Executive's employment.

      Section  10.  CERTAIN  COMPANY   PROTECTION   PROVISIONS.   The  following
provisions  apply  for  the  protection  of  the  Company,   and  shall  survive
indefinitely, beyond the duration of this Agreement:

            (a)  NONCOMPETITION.  During the Employment  Period and for a period
for two (2) years thereafter (the "RESTRICTED PERIOD"),  the Executive shall not
directly or indirectly compete with the Company by owning,  managing,  managing,
controlling or  participating  in the ownership,  management or control of or be
employed by or engaged in any  Competitive  Business (as defined  herein) in any
location in the United States in which the Company is doing business (the "TRADE
AREA").  As used herein,  a  "COMPETITIVE  BUSINESS"  is any other  corporation,
partnership, proprietorship, firm or other business entity which is engaged in a
"core  business  of the  Company."  A  "core  business  of the  Company"  is the
development,  manufacture, distribution or sale of a particular type of product,
reagent or kit involved in the  detection  or  preparation  of nucleic  acids in
which the Company or DNA Sciences, Inc., a California corporation,  has invested
or expended more than Two Hundred  Thousand  Dollars  ($200,000) in the eighteen
(18) months prior to the "Measurement Date" (as defined herein). The MEASUREMENT
DATE shall be the point in time during the Restricted  Period that the Executive
becomes  associated with a Competitive  Business  whether such association is by
employment,   engagement  or  by  directly  or  indirectly   owning,   managing,
controlling  or  participating  in the  ownership,  management  or  control of a
Competitive  Business.  In the event of any period of investment or  expenditure
which  commenced  less than eighteen (18) months from the  Measurement  Date the
amount  invested or expended  shall be  annualized  for such eighteen (18) month
period.

            Notwithstanding  the above,  the Executive may become employed by or
engaged  by a  "Competitive  Business"  so  long  as the  Executive  (a) was not
directly  involved with or  participating  in the areas of "core business of the
Company" which makes the other business a "Competitive  Business", or (b) if the
Executive is not involved,  directly,  in that part of the Competitive  Business
which is competitive  with the "core business of the Company." In addition,  the
Executive  may be  employed by or engaged by any  business  which after the date
hereof  becomes  a  "Competitive  Business,"  if the  employment  or  engagement
occurred prior to the Company entering into a new "core business of the Company"
(whether by acquisition or through the Company's own  initiative),  which caused

                                       5
<PAGE>

such other business to become a Competitive Business.  Also, this section is not
violated  if the  Executive  owns no more than 5% of the  stock of any  publicly
traded Competitive Business.

            (b)  NON-INTERFERENCE.  During the Restricted  Period, the Executive
shall not for his own  benefit  or the  benefit of any other  person,  induce or
solicit  any  employee  of the  Company or any person  doing  business  with the
Company to terminate  his or her  employment or business  relationship  with the
Company or otherwise interfere with any such relationship.

            (c) CONFIDENTIALITY.  The Executive agrees and acknowledges that, by
reason of the nature of his duties as an officer and  employee,  he will have or
may have access to and become  informed of confidential  and secret  information
which  is a  competitive  asset  of the  Company  ("CONFIDENTIAL  INFORMATION"),
including  without  limitation any lists of customers or subscribers,  financial
statistics,  research data or any other statistics and plans contained in profit
plans,  capital  plans,  critical issue plans,  strategic  plans or marketing or
operation  plans or other trade  secrets of the Company and any of the foregoing
which belong to any person or company but to which the  Executive has had access
by reason of his employment  relationship with the Company. The Executive agrees
faithfully to keep in strict confidence, and not, either directly or indirectly,
to make known, divulge,  reveal,  furnish, make available or use (except for use
in  the  regular  course  of  his  employment   duties)  any  such  Confidential
Information.  The Executive  acknowledges that all manuals,  instruction  books,
price  lists,  experiment  logs or papers,  information  and  records  and other
information and aids relating to the Company's  business,  and any and all other
documents containing Confidential  Information furnished to the Executive by the
Company or otherwise acquired or developed by the Executive,  shall at all times
be the property of the Company.  Upon termination of the Employment  Period, the
Executive  shall return to the Company any such property or documents  which are
in his  possession,  custody or control,  but his obligation of  confidentiality
shall survive such  termination  of the  Employment  Period until and unless any
such  Confidential  Information  shall  have  become,  through  no  fault of the
Executive,  generally known to the trade. The obligations of the Executive under
this  subsection are in addition to, and not in limitation or preemption of, all
other obligations of confidentiality which the Executive may have to the Company
under general legal or equitable principles.

            (d)  REMEDIES.  It is  expressly  agreed  by the  Executive  and the
Company that these  provisions are reasonable for purposes of preserving for the
Company its business,  goodwill and Confidential Information.  It is also agreed
that if any provision is found by a court having jurisdiction to be unreasonable
because  of  scope,  area or time,  then  that  provision  shall be  amended  to
correspond in scope, area and time to that considered  reasonable by a court and
as  amended  shall  be  enforced  and  the  remaining  provisions  shall  remain
effective. In the event of any breach of these provisions by the Executive,  the
parties  recognize and  acknowledge  that a remedy at law will be inadequate and
the Company may suffer irreparable  injury. The Executive  acknowledges that the
services to be rendered by him are of a character  giving them  peculiar  value,
the loss of which cannot be adequately compensated for in damages;  accordingly,
the Executive  consents to injunctive  and other  appropriate  equitable  relief
without  the  posting  of any type of bond or  surety  upon the  institution  of
proceedings  therefor by the Company in order to protect the  Company's  rights.

                                       6
<PAGE>

Such relief shall be in addition to any other relief to which the Company may be
entitled at law or in equity.

      Section 11.  INDEMNIFICATION.  As an officer of the Company, the Executive
shall be  indemnified  by the  Company in  accordance  with the  indemnification
provisions  of the  Company's  Bylaws  as in  effect  on the  date  hereof,  and
otherwise to the extent to which officers of a corporation  organized  under the
laws of Florida may be indemnified  pursuant to Section  607.0850 of the Florida
Statutes,  as the  same may be  amended  from  time to time  (or any  subsequent
statute of similar  tenor and effect),  subject to the terms and  conditions  of
such statute.

      Section  12.  SUCCESSORS  AND  ASSIGNS.  Except as  hereinafter  expressly
provided,  the  agreements,  covenants,  terms and  provisions of this Agreement
shall bind the  respective  heirs,  executors,  administrators,  successors  and
assigns of the parties.

      This  Agreement  is personal  in nature and neither of the parties  hereto
shall,  without the consent of the other,  assign or transfer this  Agreement or
any rights or  obligations  hereunder,  except as provided  in this  Section 12.
Without  limiting  the  foregoing,  the  Executive's  right to receive  payments
hereunder shall not be assignable or transferable,  whether by pledge,  creation
of a  security  interest  or  otherwise,  and in  the  event  of  any  attempted
assignment  or transfer in  contravention  of this Section 12 the Company  shall
have no liability to pay to the purported  assignee or transferee  any amount so
attempted to be assigned or transferred.

      Section  13.  NOTICES.  All  notices  and  other  communications  that are
required or may be given under this  Agreement  shall be in writing and shall be
delivered  personally or by certified mail  addressed to the party  concerned at
the following addresses:

If to the Company:         Genetic Vectors, Inc.
                           5201 N.W. 77th Avenue
                           Suite 100
                           Attn: Mead M. McCabe, Jr., President

With a copy to:            Kirkpatrick & Lockhart LLP
                           201 South Biscayne Boulevard
                           Miami Center, 20th Floor
                           Miami, Florida 33131
                           Attn:  Clayton E. Parker, Esq.

If to Executive:           Jerome Streifel

                           ---------------------
                           ---------------------
                           ---------------------

With a copy to:            William R. Soderstrom, Esquire
                           622 North Water Street, Suite 500
                           Milwaukee, Wisconsin 92024

                                       7
<PAGE>

All notices shall be effective upon receipt.

      Section 14. WAIVER; REMEDIES CUMULATIVE.  No waiver of any right or option
hereunder  by any party shall  operate as a waiver of any other right or option,
or the same  right  or  option  as  respects  any  subsequent  occasion  for its
exercise,  or of any legal remedy.  No waiver by any party of any breach of this
Agreement  or of any  agreement  or covenant  contained  herein shall be held to
constitute  a waiver of any other breach or a  continuation  of the same breach.
All remedies  provided by this  Agreement are in addition to all other  remedies
provided under this Agreement or applicable law.

      Section 15.  GOVERNING LAW;  SEVERABILITY.  This Agreement and its various
terms, provisions,  covenants and agreements, and the performance thereof, shall
be construed,  interpreted  and enforced under and with reference to the laws of
the State of Florida.  It is the  intention of the Company and the  Executive to
comply fully with all laws and matters of public  policy  relating to employment
agreements and  restrictive  covenants,  and this  Agreement  shall be construed
consistently with such laws and public policy to the extent possible.  If and to
the extent any one or more covenants,  agreements,  terms and provisions of this
Agreement  or  any  portion  or  portions  thereof  shall  be  held  invalid  or
unenforceable  by a  court  of  competent  jurisdiction,  then  such  covenants,
agreements, terms and provisions (or portions thereof) shall be deemed separable
from the remaining covenants, agreements, terms and provisions of this Agreement
and such holding shall in no way affect the validity or enforceability of any of
the other covenants, agreements, terms and provisions hereof.

      Section  16.   MISCELLANEOUS.   This  Agreement   constitutes  the  entire
understanding  of the parties  hereto with respect to the subject matter hereof.
This  Agreement  may not be  modified,  changed or  amended  except in a writing
signed by each of the parties  hereto.  This Agreement may be signed in multiple
counterparts,  each of which shall be deemed an original hereof. The captions of
the several  sections and  subsections  of this  Agreement are not a part of the
context hereof,  are inserted only for convenience in locating such sections and
subsections and shall be ignored in construing this Agreement.

                           [SIGNATURE PAGE TO FOLLOW]

                                       8
<PAGE>

      IN WITNESS WHEREOF, the Company and Executive have executed this Agreement
as of the date first above written.

                                   EXECUTIVE:

                                   JEROME STREIFEL

                                   ----------------------------------------

                                    COMPANY:

                                    GENETIC VECTORS, INC.,
                                    A FLORIDA CORPORATION

                                    By:
                                   ----------------------------------------
                                        Its:
                                             ------------------------------

                                       9
<PAGE>

                              STOCK OPTION ADDENDUM
                                       TO
                         EXECUTIVE EMPLOYMENT AGREEMENT
                                     BETWEEN
                              GENETIC VECTORS, INC.
                                       AND
                                 JEROME STREIFEL

      Subject  to  all  of  the  terms  and  conditions  contained  herein,  the
undersigned,  Genetic  Vectors,  Inc., a Florida  corporation  (the  "COMPANY"),
hereby grants to JEROME  STREIFEL  (the  "Executive")  the following  options to
purchase shares (the "EXECUTIVE OPTION SHARES") of the Company's $.001 par value
common stock (the "COMMON SHARES") as follows:

      The Company and the Executive hereby agree as follows:

      Subject to all of the terms and conditions  contained herein,  the Company
hereby grants to Executive the following options to purchase Common Shares:

      OPTIONS.  The Company  hereby  grants to  Executive  the right and option,
pursuant to the  Company's  1999 Stock  Incentive  Plan,  to  purchase  from the
Company Sixty Thousand (60,000) Common Shares (the "OPTIONS") upon the following
terms and conditions:

       TERM OF OPTIONS. The Options shall be effective throughout the Employment
Period and for a period of ten years from the date of grant.

       PURCHASE  PRICE.  The purchase price for the Option shall be equal to the
Closing Price of the Common Shares on the date of grant.

       OPTIONS  NON-TRANSFERABLE.  The option rights with respect to the Options
are  non-transferable and are personal to Executive and may be exercised only by
Executive and non one else.

       TIME OF EXERCISE.  Except as set forth herein, there are no conditions to
the exercise or the exercisability by the Executive of the Options.

      VESTING OF OPTIONS.  Subject to the  provisions  of Section 3 hereof,  the
Options  shall vest as follows:  (1) one-third on the first  anniversary  of the
date first  written above (2)  one-third on the second  anniversary  of the date
first written above and (3) one third on the third anniversary of the date first
written  above,  provided,  however,  that  if  the  executive's  employment  is
terminated  for any reason other than death or permanent  disability (as defined
in the  Company's  1999 Stock  Option  Plan),  any and all Options that have not
vested  as of the  Employment  Termination  Date (as  defined  in the  Executive
Employment Agreement) shall expire on such Employment Termination Date.

      SECURITIES ACT, ETC. In the absence of an effective Registration Statement
under the  Securities  Act of 1933,  as from time to time in effect (the "ACT"),
relating  thereto,  the Company  shall not be required to register a transfer of
shares  delivered  or  deliverable  upon  exercise  of the  Options  ("DELIVERED
SHARES")  on its books  unless  the  Company  shall have been  provided  with an
opinion of counsel  satisfactory to it prior to such transfer that  registration
under the Act is not required in connection  with the  transaction  resulting in
such transfer.  Each certificate  evidencing Delivered Shares or issued upon any
transfer of  Delivered  Shares  shall bear an  appropriate  restrictive  legend,
except that such  certificate  shall not bear such a  restrictive  legend if the

                                       10
<PAGE>

opinion of counsel  referred to above is to the further  effect that such legend
is not required in order to establish compliance with the provisions of the Act.
Nothing in this  paragraph 2 shall  modify or  otherwise  affect the  provisions
applicable to the Delivered Shares.

      TERMINATION, EXERCISE, ETC.

      Except as set forth herein, the Options shall expire and terminate, to the
extent  not  previously  exercised,  as to all  Executive  Option  Shares on the
Employment Termination Date.

      Unless the Board of Directors  (the  "BOARD")  determines  otherwise,  the
Executive's  rights in  respect of any  outstanding  Options  shall  immediately
terminate and no shares (or cash) shall be delivered with respect to the Options
if prior to the delivery of the Executive  Option  Shares,  (i) the Executive is
terminated  for cause or (ii) the Executive  engages in conduct as determined by
the Board to violate the non-competition or non-disclosure  provisions set forth
in Section 10 of the Executive  Employment Agreement or (iii) failure to provide
the representations and certifications required in Section 3 hereof.

      Subject to the preceding  paragraph 3(a) and the other  provisions of this
addendum,  the  Options  may,  to the  extent  exercisable  but  not  previously
exercised,  be exercised at any time and from time to time, in whole or in part,
by written notice delivered to the Company signed by the Executive or the Estate
thereof. Such notice shall state the number of Option Shares in respect to which
the Options are being  exercised,  and shall  contain such  representations  and
warranties of the  Executive or the Estate  thereof as the Company may then deem
necessary or desirable in order to comply with federal or state  securities laws
or as may  otherwise  be  reasonably  requested  by the  Company  and  shall  be
accompanied  either (i) by payment in full (in cash, by personal check or by any
other method  acceptable to the Company) of the full  Exercise  Price in respect
thereof or (ii)  delivery to the  Company of a number of shares of Common  Stock
owned by the Executive and having a fair market value (determined reasonably and
in good faith by the Board of Directors  and, if reasonably  possible,  prior to
such exercise) equal to the full Exercise Price in respect thereof. In addition,
the Company  shall have the right to require  that the  Executive  or the Estate
thereof,  when exercising the Options in whole or in part,  remit to the Company
an amount  sufficient  to satisfy any federal,  state or local  withholding  tax
requirements  (or make other  arrangements  satisfactory  to the  Company)  with
regard to such taxes prior to the delivery of any Delivered  Shares  pursuant to
such exercise,  including,  without limitation,  by withholding Delivered Shares
otherwise deliverable upon such exercise,  and, if requested by the Executive or
such Estate, the Company shall so withhold at least a number of Delivered Shares
requested to be so withheld by the  Executive at the time of such  exercise.  As
soon as practicable after such notice and payment shall have been received,  the
Company shall deliver a certificate or certificates  representing  the number of
Delivered Shares with respect to which the Options were exercised, registered in
the name of the Executive or such other name as the Executive shall direct.

      All  Delivered  Shares that shall be  purchased  upon the  exercise of the
options as provided herein shall be fully paid and non-assessable.

      CERTAIN CONDITIONS.  In the event the Company (i) pays a dividend or makes
a distribution on its Common Stock,  (ii)  subdivides its outstanding  shares of
Common Stock into a greater  number of shares,  (iii)  combines its  outstanding
shares  of  Common  Stock  into  a  smaller  number  of  shares,  (iv)  makes  a
distribution  on its  Common  Stock in shares of its  capital  stock  other than
Common Stock, (v) issues by  reclassification  of its Common Stock any shares of
its  capital  stock,   or  (vi)   consummates  any  merger   reorganization   or
consolidation  pursuant to which any securities or other consideration is issued
to the holders of  outstanding  shares of capital  stock of the Company (each an
"ADJUSTMENT  EVENT"),  then the Options granted to the Executive hereunder shall

                                       11
<PAGE>

be so adjusted and upon the exercise of such  Options,  the  Executive  shall be
entitled to receive such securities of the Company or other consideration as the
Executive would have held immediately  after the consummation of such Adjustment
Event had the  Delivered  Shares  issuable  upon such  exercise been held by the
Executive on such record date.

      5. RIGHT OF OFFSET. The Company shall have the right to offset against the
obligation to deliver  Executive Option Shares (or cash) under this Stock Option
Addendum (i) any amounts or  liabilities of the Executive to the Company or (ii)
any claims of the Company against the Executive.

      6. NO  RIGHTS  TO  CONTINUED  EMPLOYMENT.  Nothing  in this  Stock  Option
Addendum  or the 1999  Stock  Incentive  Plan shall be  construed  as giving the
Executive any right to continue employment or affect any right which the Company
may have to  terminate  or alter  the terms and  conditions  of the  Executive's
Employment.

      7. BOARD OF DIRECTORS.  The Board shall have full  discretion with respect
to any  actions to be taken or  determined  to be made in  connection  with this
Stock  Option  Addendum  and its  determinations  shall be  final,  binding  and
conclusive.

      8.  AMENDMENT BY BOARD.  The Board reserves the right at any time to amend
the terms and conditions  set forth in this Stock Option  Addendum and the Board
may amend the 1999 Stock Incentive Plan in any respect.

      9. MISCELLANEOUS.  Except as specifically  otherwise provided in Section 4
hereof as to exercise by the Executive's Estate, the Options may not be assigned
or transferred,  in whole or in part, whether by operation of law, upon death or
otherwise, by the Executive without the written consent of the Company which the
Company may  withhold in its sole and absolute  discretion,  with or without any
reason.  The Options are not intended to constitute and "incentive stock option"
as that term is used in Section 422 of the  Internal  Revenue  Code of 1986,  as
amended,  and shall not be treated as incentive stock options. The Options shall
be  governed  by and  construed  in  accordance  with the  laws of the  State of
Florida.

                                          GENETIC VECTORS, INC.

                                          By:
                                             ---------------------------------
                                          Name:
                                               -------------------------------
                                          Title:
                                                ------------------------------

                                       12

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