Document:

Form of Amended and Restated Restricted Stock Unit Award Agreement

 Exhibit 10.9.1 
 MAXYGEN, INC. 
 2006 EQUITY INCENTIVE PLAN 
 FORM OF AMENDED AND RESTATED 
 RESTRICTED STOCK UNIT AWARD AGREEMENT 
 Unless otherwise defined herein, the terms defined in the Maxygen, Inc. 2006 Equity
Incentive Plan (the “Plan”) shall have the same defined meanings in this Restricted Stock Unit Award Agreement (the “Agreement”). 
 I. NOTICE OF GRANT OF RESTRICTED STOCK UNIT 
 Name:
[                                    ] (referred to herein as
“Participant” or “you”) 
 You have been granted an Award of Restricted Stock Units (“RSUs”), subject to the
terms and conditions of the Plan and this Agreement, as follows: 
  

			
	Date of Grant:	 	 [                                ]

		
	Total Number of RSUs Granted:	 	 [                                ]

 Vesting Schedule: The RSUs awarded by this Agreement shall vest in accordance with the following
schedule: 
 [25% of the RSUs awarded by this Agreement shall vest on May 1, 2009 and the remaining 75% shall vest on May 3, 2010],
subject to your remaining a Consultant, Employee or Director through those dates; provided, however, that, subject to Participant entering into and not revoking a release of claims in substantially the form attached hereto as Exhibit A within
forty-five (45) days of the accelerated vesting event, 100% of the unvested RSUs hereunder shall vest earlier upon the first to occur of (i) Participant’s involuntary employment termination without Cause (as defined herein), or
(ii) ninety (90) days, or such shorter period of time as is determined by the management of the Company (or the applicable successor to the Company) in its sole discretion, following (A) a Change of Control (as defined herein) or
(B) the Participant’s termination of Company employment following their acceptance of an employment offer with a person or Group that has acquired any asset from the Company; provided that the solicitation of such employment is authorized
in writing (or by e-mail) by a duly authorized officer of the Company (other than Participant). 
 For the purposes of this Agreement,
“Cause” means your willful and continued failure to substantially perform your duties with the Company (other than as a result of physical or mental disability) after a written demand for substantial performance is delivered to you by the
Company, which demand specifically identifies the manner in which the Company believes that you have not substantially performed your duties and that has not been cured by you within fifteen (15) days following your receipt of the written
demand; (ii) your commission of a felony (other than a traffic-related offense) that in the written determination of the Company is likely to cause or has caused material injury to the Company’s business; (iii) your dishonesty with
respect to a significant matter relating to the Company’s business; or (iv) your material breach of any agreement by and between you and the Company, which material breach has not been cured within fifteen (15) days following your
receipt of written notice from the Company identifying such material breach. 
 For the purposes of this Agreement, “Change of
Control” means the occurrence of any of the following dates: 
 (i) Change in Ownership of the Company. The date that any one
person, or more than one person acting as a Group (as defined herein), acquires ownership of stock of the Company that, together with stock held by such person or group, constitutes more than fifty percent (50%) of the total fair market value
or total voting power of the stock of the Company; or 

 (ii) Change in Effective Control of the Company. Either (a) the date any one person, or more
than one person acting as a Group, acquires (or has acquired during the twelve-month period ending on the date of the most recent acquisition by such person or persons) ownership of stock of the Company possessing thirty-five percent (35%) or
more of the total voting power of the stock of the Company, or (b) the date a majority of members of the Company’s board of directors is replaced during any 12-month period by directors whose appointment or election is not endorsed by a
majority of the members of the Company’s board of directors before the date of the appointment or election; or 
 (iii) Change in
Ownership of a Substantial Portion of the Company’s Assets. The date that any one person, or more than one person acting as a Group, acquires (or has acquired during the twelve-month period ending on the date of the most recent acquisition
by such person or persons) assets from the Company that have a total gross fair market value equal to or more than eighty percent (80%) of the total gross fair market value of all of the assets of the Company immediately before such acquisition
or acquisitions. 
 For the purposes of this Agreement, “Group” means a group as such term is defined in Treasury
Regulation §1.409A-3(i)(5)(vi)(B). 
 II. AGREEMENT 
 1. Grant of Restricted Stock Unit. The Company hereby grants to the Participant named in the Notice of the Grant of Restricted Stock Units attached as Part I of this Agreement (“Notice of
Grant”) an award of RSUs, as set forth in the Notice of Grant and subject to the terms and conditions in this Agreement and the Plan. 
 2. Company’s Obligation. Each RSU represents the right to receive a Share on the vesting date. Unless and until the RSUs vest, the Participant will have no right to receive Shares under such RSUs. Prior to actual
distribution of Shares pursuant to any vested RSUs, such RSUs will represent an unsecured obligation of the Company, payable (if at all) only from the general assets of the Company. 
 3. Vesting Schedule. Subject to paragraph 5, Plan Sections 15 and 16 and any other relevant Plan provisions, the RSUs awarded by this Agreement
will vest in the Participant according to the vesting schedule specified in the Notice of Grant. 
 4. Dividend Equivalents; Property
Distributions. From and after the effective date hereof, if the Company declares and pays a cash dividend to holders of Common Stock (a “Cash Dividend”) or if the Company distributes any securities (other than Shares) or other Company
property to holders of Common Stock (a “Property Distribution”), then the Participant shall receive for each RSU held by the Participant as of the record date of such Cash Dividend or Property Distribution (i) a Dividend Equivalent
equal to the per Share Cash Dividend, and (ii) a credit for any Property Distribution equal to the per Share Property Distribution. All such credits shall be made to a notional account established for the Participant. With respect to all or a
portion of any Property Distribution, the Administrator may, in its discretion, in lieu of crediting such notional account with the securities or other Company property comprising the Property Distribution, credit the Participant’s notional
account with a cash amount equal to the fair market value, as determined in the Administrator’s sole discretion, of all or a portion of any such Property Distribution attributable to the RSUs. Any Dividend Equivalent or Property Distribution
payable hereunder shall be subject to the same vesting and forfeiture restrictions and conditions applicable to the underlying RSUs as specified in sections 2 and 6 of this Agreement and in the Notice of Grant and shall only be paid or settled to
the extent that the underlying RSUs vest. 
 5. Forfeiture upon Termination as Employee, Director or Consultant. Notwithstanding any
contrary provision of this Agreement or the Notice of Grant, if the Participant terminates service as an Employee, Director or Consultant for any or no reason prior to vesting (except as set forth in the Notice of Grant), the unvested RSUs awarded
by this Agreement, together with any Dividend Equivalents or Property Distributions attributable to such unvested RSUs will thereupon be forfeited at no cost to the Company. 
  

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 6. Payment after Vesting. Any RSUs that vest in accordance with paragraph 3 will be paid to the
Participant (or in the event of the Participant’s death, to his or her estate) in Shares as soon as administratively feasible after the vesting date, Delivery of any cash payment or property credited to a Participant with respect to Dividend
Equivalents or Property Distributions attributable to RSUs shall be made on or about the date the Shares underlying the RSUs are distributed to the Participant. To the extent determined appropriate by the Company, the minimum statutorily required
federal, state and local withholding taxes with respect to such RSUs, Dividend Equivalents or Property Distributions will be paid by reducing the number of Shares, cash payments or other property, as applicable, actually paid or delivered to the
Participant. 
 7. Payments after Death. Any distribution or delivery to be made to the Participant under this Agreement will, if the
Participant is then deceased, be made to the administrator or executor of the Participant’s estate. Any such administrator or executor must furnish the Company with (a) written notice of his or her status as transferee, and
(b) evidence satisfactory to the Company to establish the validity of the transfer and compliance with any laws or regulations pertaining to said transfer. 
 8. Rights as Stockholder. Except as provided in paragraph 4 of this Agreement, neither the Participant nor any person claiming under or through the Participant will have any of the rights or privileges of a
stockholder of the Company in respect of any Shares deliverable hereunder unless and until certificates representing such Shares will have been issued, recorded on the records of the Company or its transfer agents or registrars, and delivered to the
Participant or Participant’s broker. 
 9. No Effect on Employment. The Participant’s employment with the Company and its
Subsidiaries is on an at-will basis only. Accordingly, the terms of the Participant’s employment with the Company and its Subsidiaries will be determined from time to time by the Company or the Subsidiary employing the Participant (as the case
may be), and the Company or the Subsidiary will have the right, which is hereby expressly reserved, to terminate or change the terms of the employment of the Participant at any time for any reason whatsoever, with or without good cause or notice.

 10. Notices. All notices and other communications under this Agreement shall be in writing or posted electronically on the E*TRADE
Securities LLC website. Unless and until Participant is notified in writing to the contrary, all notices, communications, and documents directed to the Company and related to the Agreement shall be delivered to Maxygen, Inc., 515 Galveston Drive,
Redwood City, CA 94063, Attention: Stock Administration. Unless and until the Company is notified in writing to the contrary, all notices, communications, and documents directed to Participant and related to this Agreement shall be mailed to
Participant’s last known address as shown on the Company’s books or posted electronically on the E*TRADE Securities LLC website. Notices and communications shall be delivered by hand, mailed by first class mail, postage prepaid, sent by
reputable overnight courier or posted electronically on the E*TRADE Securities LLC website. All mailings and deliveries related to this Agreement shall be deemed received when actually received, if by hand delivery, two business days after mailing,
if by mail, the next business day after being sent by reputable overnight courier, or 30 days after the date of posting for notices posted electronically on the E*TRADE Securities LLC website. 
 11. Grant is Not Transferable. Except to the limited extent provided in paragraph 8, this grant and the rights and privileges conferred hereby,
including rights to any Dividend Equivalents or Property Distributions attributable to the RSUs, will not be transferred, assigned, pledged or hypothecated in any way (whether by operation of law or otherwise) and will not be subject to sale under
execution, attachment or similar process. Upon any attempt to transfer, assign, pledge, hypothecate or otherwise dispose of this grant, or any right or privilege conferred hereby, or upon any attempted sale under any execution, attachment or similar
process, this grant and the rights and privileges conferred hereby immediately will become null and void. 
 12. Binding Agreement.
Subject to the limitation on the transferability of this grant contained herein, this Agreement will be binding upon and inure to the benefit of the heirs, legatees, legal representatives, successors and assigns of the parties hereto. 
  

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 13. Additional Conditions to Issuance of Stock. If at any time the Company will determine, in its
discretion, that the listing, registration or qualification of the Shares upon any securities exchange or under any state or federal law, or the consent or approval of any governmental regulatory authority is necessary or desirable as a condition to
the issuance or delivery to the Participant (or his or her estate) of Shares or any securities or other property comprising Property Distributions, such issuance or delivery will not occur unless and until such listing, registration, qualification,
consent or approval will have been effected or obtained free of any conditions not acceptable to the Company. The Company will make all reasonable efforts to meet the requirements of any such state or federal law or securities exchange and to obtain
any such consent or approval of any such governmental authority. 
 14. Plan Governs. This Agreement and the Notice of Grant are
subject to all terms and provisions of the Plan. In the event of a conflict between one or more provisions of this Agreement or the Notice of Grant and one or more provisions of the Plan, the provisions of the Plan will govern. 
 15. Administrator Authority. The Administrator will have the power to interpret the Plan and this Agreement and to adopt such rules for the
administration, interpretation and application of the Plan as are consistent therewith and to interpret or revoke any such rules (including, but not limited to, the determination of whether or not any RSUs have vested). All actions taken and all
interpretations and determinations made by the Administrator in good faith will be final and binding upon Participant, the Company and all other interested persons. No member of the Administrator will be personally liable for any action,
determination or interpretation made in good faith with respect to the Plan or this Agreement. 
 By your signature and the signature of the
Company’s representative below, you and the Company agree that this Award is granted under and governed by the terms and conditions of the Plan and this Agreement. Participant has reviewed the Plan and this Agreement in their entirety, has had
an opportunity to obtain the advice of counsel prior to executing this Agreement and fully understands all provisions of the Plan and this Agreement. Participant hereby agrees to accept as binding, conclusive and final all decisions or
interpretations of the Administrator upon any questions relating to the Plan and this Agreement. Participant further agrees to notify the Company upon any change in the residence address indicated below. 
  

					
	PARTICIPANT:	 	MAXYGEN, INC.
			
	  
	 	By:	 	  

  

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 Exhibit A 
 to Restricted Stock Unit Agreement 
 MAXYGEN, INC. 
 AGREEMENT AND RELEASE 
 I hereby
confirm my obligations under the Confidential Information, Secrecy and Invention Agreement that I have previously entered into with the Company. 
 I acknowledge that I have read and understand Section 1542 of the California Civil Code that reads as follows: 
 A general
release does not extend to claims which the creditor does not know or suspect to exist in his favor at the time of executing the release, which if known by him must have materially affected his settlement with debtor. 
 I hereby expressly waive and relinquish all rights and benefits under that section and any law of any jurisdiction of similar effect with respect to my
release of any claims I may have against the Company. 
 Except as otherwise set forth in this Agreement and Release (the
“Release”) and except for obligations of the Company set forth in the Restricted Stock Unit Agreement entered into between the Company and me, I hereby release, acquit and forever discharge the Company, its parents and subsidiaries, and
their officers, directors, agents, servants, employees, shareholders, successors, assigns and affiliates, of and from any and all claims, liabilities, demands, causes of action, costs, expenses, attorneys fees, damages, indemnities and obligations
of every kind and nature, in law, equity, or otherwise, known and unknown, suspected and unsuspected, disclosed and undisclosed (other than any claim for indemnification I may have as a result of any third party action against me based on my
employment with the Company), arising out of or in any way related to agreements, events, acts or conduct at any time prior to and including the Effective Date of this Release (as defined below), including but not limited to: all such claims and
demands directly or indirectly arising out of or in any way connected with my employment with the Company or the termination of that employment, including but not limited to, claims of intentional and negligent infliction of emotional distress, any
and all tort claims for personal injury, claims or demands related to salary, bonuses, commissions, stock, stock options, or any other ownership interests in the Company, vacation pay, fringe benefits, expense reimbursements, severance pay, or any
other form of compensation; claims pursuant to any federal, state or local law or cause of action including, but not limited to, the federal Civil Rights Act of 1964, as amended; the federal Age Discrimination in Employment Act of 1967, as amended
(“ADEA”); the federal Americans with Disabilities Act of 1990; the California Fair Employment and Housing Act, as amended; tort law; contract law; wrongful discharge; discrimination; fraud; defamation; emotional distress; and breach of the
implied covenant of good faith and fair dealing; provided, however, that nothing in this paragraph shall be construed in any way to release the Company from its obligation to [(i) indemnify me pursuant to any applicable indemnification agreement and
to provide me with continued coverage under the Company’s directors and officers liability insurance policy to the same extent that it has provided such coverage to previously departed officers and directors of the Company, (ii) provide
the benefits to me set forth in the Change of Control Agreement, as amended to date, entered into between the Company and me][for officers only] or (iii) provide the benefits to me set forth in the Restricted Stock Unit Agreement entered
into between the Company and me. 
 I acknowledge that I am knowingly and voluntarily waiving and releasing any rights I may have under ADEA.
I also acknowledge that the consideration given for the waiver and release in the preceding paragraph hereof is in addition to anything of value to which I was already entitled. If and only if I am covered by ADEA, I further acknowledge that I have
been advised by this writing, as required by the ADEA, that: (A) my waiver and release do not apply to any rights or claims that may arise after the Effective Date of this Release; (B) I have the right to consult with an attorney prior to
executing this Release; (c) I have twenty-one (21) days to consider this 

  

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Release (although I may choose to voluntarily execute this Release earlier); (D) I have seven (7) days following the execution of this Release to
revoke the Release; and (E) this Release shall not be effective until the date upon which the revocation period has expired, which shall be the eighth day after this Release is executed by me (the “Effective Date”). If I am not
covered by ADEA, I acknowledge that this Agreement shall be effective as of the date upon which this Release has been executed by me (the “Effective Date”). 
  

			
	By:	 	  

		 	EMPLOYEE
		
	Date:	 	  

  

 6Sixth Amendment to Lease

 Exhibit 10.10.6 
 SIXTH AMENDMENT TO LEASE 
 This Sixth Amendment to Lease (“Amendment”) is entered into, and
dated for reference purposes, as of February 6, 2009 (the “Execution Date”) by and between METROPOLITAN LIFE INSURANCE COMPANY, a New York corporation (“Metropolitan”), as Landlord (“Landlord”), and MAXYGEN, INC.,
a Delaware corporation (“Maxygen”), as Tenant (“Tenant”), with reference to the following facts (“Recitals”): 
 A. Landlord and Tenant entered into that Lease (the “Original Lease”) dated as of October 21, 1998 for certain premises consisting of the entire building known as 515 Galveston Drive (the “Original Premises” or
“515 Galveston Premises”) Redwood City, California, as amended by that First Amendment to Lease dated as of February 26, 1999 (the “First Amendment”) for the lease of Expansion Space A (which may also be referred to as the
“220 Penobscot Premises”), that certain written Second Amendment To Lease dated October 24, 2000 (the “Second Amendment”) for the lease of Expansion Space B (which may also be referred to as the “200 Penobscot
Premises”), that certain written Third Amendment To Lease dated October 22, 2003 (the “Third Amendment”) for the surrender of all of the 220 Penobscot Premises and part of the 200 Penobscot Premises, that certain written Fourth
Amendment To Lease dated December, 2004 (the “Fourth Amendment”) for extension of the Term of the 515 Galveston Premises, and that certain written Fifth Amendment to Lease dated as of August 24, 2008 (“Fifth Amendment”), all
as more particularly described in the Original Lease, First Amendment, Second Amendment, Third Amendment, Fourth Amendment and Fifth Amendment (collectively, the “Existing Lease”, and the Premises as of the Execution Date is collectively
referred to as the “Premises”). 
 B. Landlord and Tenant desire to extend the current Term for the Premises in accordance with
Tenant’s exercise of its Option To Extend, as set forth in Section 6 of the Fifth Amendment, which is also known as the 515 Galveston Premises and which consists of an agreed 31,166 square feet of Rentable Area, and provide for other
amendments of the Existing Lease as more particularly set forth below. 
 NOW, THEREFORE, in consideration of the foregoing, and of the
mutual covenants set forth herein and of other good and valuable consideration, the receipt and adequacy of which are hereby acknowledged, the parties hereto agree as follows: 
 Section 1. Scope of Amendment; Defined Terms. Except as expressly provided in this Amendment, the Existing Lease shall remain in full
force and effect. Should any inconsistency arise between this Amendment and the Existing Lease as to the specific matters which are the subject of this Amendment, the terms and conditions of this Amendment shall control. The term “Lease”
as used herein and in the Existing Lease shall refer to the Existing Lease as modified by this Amendment, except as expressly provided in this Amendment. All capitalized terms used in this Amendment and not defined herein shall have the meanings set
forth in the Existing Lease unless the context clearly requires otherwise. 
 Section 2. Extension of Term for 515 Galveston
Premises. Notwithstanding any provision of the Existing Lease to the contrary, Landlord and Tenant acknowledge and agree as follows: 
 (a) The current Term pursuant to the Existing Lease will expire on February 28, 2009. 
 (b) The Term is hereby extended for
the period of twelve (12) months (the “Third Extended Term”) commencing on March 1, 2009 (the “Third Extension Commencement Date”) and expiring February 28, 2010 (hereafter, the “Expiration Date” in lieu
of the date provided in the Existing Lease), unless sooner terminated pursuant to the terms of the Lease. 
 (c) Landlord and Tenant
acknowledge and agree that this Amendment provides all rights and obligations of the parties with respect to extension of the current Term, whether or not in accordance with any other provisions, if any, of the Existing Lease regarding renewal or
extension, and any such provisions, options or rights for renewal or extension provided in the Existing Lease are hereby deleted as of the Execution Date, and without 

  

 1 

 
limiting the generality of the foregoing, Tenant and Landlord acknowledge and agree that the Option to Extend set forth in Section 6 of the Fifth
Amendment is hereby deleted as of the Execution Date. 
 Section 3. Monthly Base Rent for Third Extended Term.
Notwithstanding any provision of the Existing Lease to the contrary, commencing on the Third Extension Commencement Date and continuing through the Expiration Date of the Third Extended Term, the amount of Monthly Base Rent due and payable by Tenant
for the Premises shall be as set forth in the table below: 
  

							
	 Period from/to (inclusive)
	  	Monthly Installment of
Monthly Base Rent	  	Monthly Rate/Rentable Sq. Ft.
	 Months 01 – 12
	  	$	70,123.50	  	$	2.25

 Section 4. Tenant’s Share of Operating Expenses. Notwithstanding any
provision of the Existing Lease to the contrary, the parties acknowledge and agree that the Rentable Area of Phase I is 301,824, and commencing on the Third Extension Commencement Date and continuing through the Expiration Date of the Third Extended
Term, Tenant shall continue to pay Tenant’s Share of Operating Expenses as set forth in Article Four of the Existing Lease, and as of the Third Extension Commencement Date, Tenant’s Share for the Premises continues to be as follows:

  

				
	 Tenant’s Building Share:
	  	100.00	%
	 Tenant’s Phase Share:
	  	10.33	%
	 Tenant’s Project Share:
	  	5.80	%

 Section 5. “AS IS” Condition. Tenant acknowledges that Tenant
presently occupies and has occupied the 515 Galveston Premises since the Commencement Date of the Original Lease. Notwithstanding any provision of the Existing Lease to the contrary, Tenant hereby leases for the Third Extended Term and accepts the
Premises in its “AS IS” condition existing on the Execution Date, without any express or implied representations or warranties of any kind by Landlord, its brokers, manager or agents, or the employees of any of them regarding the Premises;
and Landlord shall not have any obligation to construct or install any tenant improvements or alterations or to pay for any such construction or installation. 
 Section 6. Brokers. Landlord represents that it has had no dealings with any real estate broker or agent in connection with this Amendment except for Cornish & Carey Commercial which
represents Landlord (“Landlord’s Broker”), and it knows of no other real estate broker or agent who is entitled to a commission in connection with this Amendment. Landlord agrees to indemnify, protect, defend and hold harmless Tenant
against and from all claims, liability, loss, damage, cost and expense arising out of any claims for brokerage commissions or fees by any broker or agent claiming to represent Landlord in connection with the subject matter of this Amendment. Tenant
represents that it has had no dealings with any real estate broker or agent in connection with this Amendment except for Landlord’s Broker, and it knows of no other real estate broker or agent who is entitled to a commission in connection with
this Amendment. Tenant agrees to indemnify, protect, defend and hold harmless Landlord against and from all claims, liability, loss, damage, cost and expense arising out of any claims for brokerage commissions or fees by any broker or agent claiming
to represent or to have dealt with Tenant (except Landlord’s Broker) in connection with the subject matter of this Amendment. The foregoing representations and obligations shall survive the expiration or sooner termination of the Lease.

 Section 7. Time of Essence. Without limiting the generality of any other provision of the Lease, time is of the essence
to each and every term and condition of this Amendment. 
 Section 8. Attorneys’ Fees. Each party to this
Amendment shall bear its own attorneys’ fees and costs incurred in connection with the discussions preceding, negotiations for and documentation of this Amendment. In the event that either party brings any suit or other proceeding with respect
to the subject matter or enforcement of this Amendment or the Lease, the parties acknowledge and agree that the provisions of Section 11.03 of the Existing Lease shall apply. 
  

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 Section 9. Effect of Headings; Recitals; Exhibits. The titles or headings of the
various parts or sections hereof are intended solely for convenience and are not intended and shall not be deemed to or in any way be used to modify, explain or place any construction upon any of the provisions of this Amendment. Any and all
Recitals set forth at the beginning of this Amendment are true and correct and constitute a part of this Amendment as if they had been set forth as covenants herein. Exhibits, schedules, plats and riders hereto which are referred to herein are a
part of this Amendment. 
 Section 10. Entire Agreement; Amendment. This Amendment taken together with the Existing Lease,
together with all exhibits, schedules, riders and addenda to each, constitutes the full and complete agreement and understanding between the parties hereto and shall supersede all prior communications, representations, understandings or agreements,
if any, whether oral or written, concerning the subject matter contained in this Amendment and the Existing Lease, as so amended, and no provision of the Lease as so amended may be modified, amended, waived or discharged, in whole or in part, except
by a written instrument executed by all of the parties hereto. 
 Section 11. Authority. Each party represents and
warrants to the other that it has full authority and power to enter into and perform its obligations under this Amendment, that the person executing this Amendment is fully empowered to do so, and that no consent or authorization is necessary from
any third party. Landlord may request that Tenant provide Landlord evidence of Tenant’s authority. 
 [Remainder of the page
intentionally left blank.] 
  

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 Section 12. Counterparts. This Amendment may be executed in duplicates or
counterparts, or both, and such duplicates or counterparts together shall constitute but one original of the Amendment, and the signature of any party to any counterpart shall be deemed a signature to, and may be appended to, any other counterpart.
Each duplicate and counterpart shall be equally admissible in evidence, and each original shall fully bind each party who has executed it. 
 IN WITNESS WHEREOF, the parties hereto have executed this Amendment as of the date first set forth above. 
  

					
	TENANT:	 	 MAXYGEN, INC.,
 a Delaware
corporation

			
		 	By:	 	 /S/    RUSSELL J.
HOWARD        

		 	Print Name:	 	Russell J. Howard
		 	Title:	 	CEO
		 		 	(Chairman of Board, President or Vice President)
			
		 	By:	 	 /S/    LAWRENCE W.
BRISCOE        

		 	Print Name:	 	Lawrence W. Briscoe
		 	Title:	 	CFO
		 		 	 (Secretary, Assistant Secretary,
 CFO or Assistant Treasurer)

		
	LANDLORD:	 	 METROPOLITAN LIFE INSURANCE COMPANY,
 a New York corporation

			
		 	By:	 	 /S/    GREG H.
HILL        

		 	Print Name:	 	Greg H. Hill
		 	Title:	 	Director

  

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