Document:

Amended and Restated Executive Employment Agreement

 Exhibit 10.1 
 InVivo Therapeutics Holdings Corp.  
 One Broadway, 14th Floor 
 Cambridge, MA 02142 
 March 5, 2012 
 Frank Reynolds 
 4116 Barberry Drive 
 Lafayette Hill, PA 19444 
  

	 	Re:	Amended and Restated Executive Employment Agreement 

 Dear Frank: 
 This letter agreement is to confirm our understanding with respect
to (i) your continued employment by InVivo Therapeutics Holdings Corp. and its subsidiaries (collectively, the “Company”), (ii) your agreement not to compete with the Company, (iii) your agreement to protect and
preserve information and property which is confidential and proprietary to the Company and (iv) your agreement with respect to the ownership of inventions, ideas, copyrights and patents which may be used in the business of the Company (the
terms and conditions agreed to in this letter are hereinafter referred to as the “Agreement”). This Agreement amends and restates, in its entirety, the Amended and Restated Executive Employment Agreement dated March 15, 2011 by and
between you and the Company, which agreement shall be of no further force or effect. In consideration of the mutual promises and covenants contained in this Agreement, and for other good and valuable consideration, the receipt and sufficiency of
which are hereby mutually acknowledged, we have agreed as follows: 
  

	 	1.	Employment. 

 (a) Subject to the terms and conditions of this Agreement, the Company will employ you, and you will be employed by the Company, as Chief Executive Officer, Chief Financial Officer and President reporting
only to the Company’s Board of Directors (the “Board”). You will have the responsibilities, duty and authority commensurate with the position of Chief Executive Officer, Chief Financial Officer and President. You will also perform
such other services of an executive nature for the Company as may be assigned to you from time to time by the Board and agreed to by you (for no additional compensation). The principal location for your employment will be the Company’s facility
located at One Broadway, 14th Floor Cambridge, MA 02142.
During the term of your employment as Chief Executive Officer and President, the Company will ensure that you are nominated and will use its best efforts to cause you to be elected, as a member of the Board and as a member of the board of directors
of any subsidiary of the Company. If your employment with the Company is terminated by the Company for Cause, you shall be deemed to have resigned, effective as of such termination, from your membership on the Board and as a director of any
subsidiary of the Company, and you hereby agree to promptly execute resignation letters documenting such resignations upon request of the Company. If your employment with the Company terminates for any reason, you shall be deemed to have resigned,
effective as of such termination, as an officer of any subsidiary of the Company, and you hereby agree to promptly execute resignation letters documenting such resignations upon request of the Company. 

(b) Devotion to Duties. For so long as you are employed by the Company, you will devote substantially all of your business
time and energies to the business and affairs of the Company, provided that, subject to Section 5(b), nothing contained in this Section 1(b) will be deemed to prevent or limit your right to manage your personal investments on your own
personal time, including, without 

 
limitation, the right to make passive investments in the securities of (i) any entity which you do not control, directly or indirectly, and which does not compete with the Company, or
(ii) any publicly held entity so long as your aggregate direct and indirect interest does not exceed 4.999 percent of the issued and outstanding securities of any class of securities of such publicly held entity, and provided, further that
nothing contained in this Agreement will be deemed to prohibit you from any involvement with any social and/or business organizations, and accepting any directorships for companies or other organizations, provided that such activities do not
interfere with the performance of your duties as an executive officer of the Company and provided that any such companies or organizations with which you become involved are not competitors of the Company or any of its subsidiaries. 

 

	 	2.	Term of Employment. 

(a) Term; Termination. Your employment with the Company shall be “at-will”, which means that either you or the
Company may terminate your employment at any time, for any reason, or for no reason, by providing notice thereof to the other party. You acknowledge that this Agreement does not constitute a contract of employment for any particular period of time
or impose on the Company any obligation to retain you as an employee. 
 (b) Definition of “Cause”. For
purposes of this Agreement, “Cause” means (i) your conviction of a felony, either in connection with the performance of your obligations to the Company or which otherwise materially and adversely affects your ability to perform such
obligations, (ii) your disloyalty or dishonesty, which results in damages or an injury to the Company, which shall include damages or an injury to the reputation of the Company, (iii) the commission by you of an act of fraud, theft or
embezzlement, or (iv) a breach by you of any material provision of this Agreement which breach is not cured within 30 days after delivery to you by the Company of written notice of such breach, provided that if such breach is not capable of
being cured within such 30 day period, you will have a reasonable additional period to cure such breach but only if you promptly commence and continue good faith efforts to cure such breach. Any determination under this Section 2(b) will be
made by the Board voting on such determination. With respect to any such determination, the Board will act fairly and in good faith and will give you and/or your legal counsel an opportunity to appear and be heard at a meeting of the Board and
present evidence on your behalf. 
 (c) Definition of “Good Reason”. For purposes of this Agreement,
“Good Reason” means any of the following: 
 (i) A change in the principal location at which you provide services to
the Company without your prior written consent, except for a new location which is within a 25 mile radius of the location at which you currently provide services to the Company; 

(ii) The failure of the Board to appoint you as CEO and President of the Company, or removal as CEO and President of the Company provided
that such failure or removal is not in connection with a termination of your employment hereunder by the Company; 
 (iii) A
material adverse change or diminution by the Company in your duties, authority or responsibilities as President and Chief Executive Officer of the Company which causes your position with the Company to become of less responsibility or authority than
your position as of immediately following the date hereof, provided that such change is not in connection with a termination of your employment hereunder by the Company; 
 (iv) The assignment to you of duties not commensurate or consistent with your position as President and Chief Executive Officer of the Company without your prior written consent; 

  
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 (v) The reduction in your Base Salary (as defined below), target bonus or other benefits
except any reduction which you agree to in writing; 
 (vi) A material breach of this Agreement by the Company that has not been
cured within 30 days after written notice thereof by you to the Company; 
 (vii) The Company ceasing to be engaged in the
business of the treatment of spinal cord injuries; 
 (viii) The Company permanently ceasing its operations; or 

(viii) Failure by the Company to obtain the assumption of this Agreement by any successor to the Company, unless such assumption occurs
automatically as a matter of law. Notwithstanding anything to the contrary above, in order to establish “Good Reason” for a termination, (i) you must provide notice to the Company of the existence of the condition giving rise to the
“Good Reason” within ninety (90) days following the initial existence of the condition and (ii) the Company has thirty (30) days following receipt of such notice to remedy such condition (the “Remedy Period”).
Further, you must actually terminate your employment for Good Reason within ten (10) days following expiration of the Remedy Period to qualify as termination of employment with the Company by you for Good Reason. 

 

	 	3.	Compensation. 

(a) Base Salary. Effective as of January 1, 2012, while you are employed by the Company, the Company will pay you a
base salary at the annual rate of $545,000 (the “Base Salary”). The Base Salary will be reviewed annually by the Governance, Nominating and Compensation Committee (the “Committee”) of the Board and will be adjusted upward (but
not downward without your consent) no less frequently than annually. The Base Salary will be payable in substantially equal installments in accordance with the Company’s payroll practices as in effect from time to time. The Company will deduct
from each such installment any amounts required to be deducted or withheld under applicable law or under any employee benefit plan in which you participate. 

(b) Annual Bonus. You will be eligible to earn an annual cash bonus pursuant to the Annual Cash Bonus
Plan for Executive Officers attached hereto as Exhibit A (the “Annual Cash Bonus Plan”) based on your performance and achievement of performance targets established by the Committee each year under the Annual Cash Bonus Plan. For 2012,
your target bonus shall be $260,000. The Committee also has discretion to grant bonuses in excess of the bonus calculated based on the level of achievement and in excess of the target bonus if it determines that such bonuses are warranted under the
circumstances and are in the best interests of the Company and its stockholders. Notwithstanding anything to the contrary, (i) on or prior to December 1st of each year, the Committee will meet and determine the extent to which objective performance targets for such year
have been achieved as of such date and, based on that determination, will authorize the prompt payment of 80% of the bonus earned based on such targets and (ii) subsequent to the end of the applicable year, the Committee will meet and determine
the total bonus earned for the applicable year, with the balance (total bonus earned less amount previously paid pursuant to the foregoing clause (i)) being paid within the first seventy-five days after the end of the calendar year in which the
bonus was earned. If your employment ends during the calendar year but you have achieved some or all of the performance targets established by the Committee for such year as of the date of termination, then you will be paid the amount of bonus
represented by such performance targets, with that bonus paid within seventy-five days of your separation from the Company, regardless of whether the termination of your employment is voluntary or involuntary. The Annual Cash Bonus Plan, as well as
the specific performance goals and business criteria with respect to fiscal 2012, shall be adopted by the Committee prior to or concurrently with the Committee’s approval of this Agreement. 

  
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 (c) Equity Compensation. You will be granted 590,000 options to purchase
shares of the Common Stock (the “Performance Option”). The exercise price for the Performance Option will be the fair market value per share of the Common Stock on the date the Performance Option is granted, which will be the date you
execute this agreement. The Performance Option (i) will be an incentive stock option to the extent permissible under applicable law, (ii) will become vested and exercisable over the course of the four-year period beginning on
January 1, 2012 and ending on December 31, 2015 (the “Vesting Period”), with equal portions vesting monthly (12,291 shares per month, with 12,323 shares vesting in the final month of the Vesting Period), (iii) will otherwise
be on terms and conditions set forth and as evidenced by a stock option agreement applicable to all stock grants made as of the date the Performance Option is granted. 
 (d) CFO Bonus. As consideration for your service as Chief Financial Officer and your efforts to find and appoint a new Chief Financial Officer, you will be granted a one-time cash bonus of
$100,000 as follows: (i) a one-time cash bonus of $50,000 upon execution of this Agreement and (ii) a one-time cash bonus of $50,000 upon the earlier of (A) the appointment of a new Chief Financial Officer (provided that you continue
to serve as Chief Financial Officer through such appointment) or (B) December 1, 2012 (provided that you continue to serve as Chief Financial Officer through such date). 

(e) Vacation. You will be entitled to paid vacation in each calendar year and paid holidays and personal days in accordance
with the Company’s policies for its senior executives as in effect from time to time, including 15 days paid vacation, 7 paid sick days, and 5 paid personal days in each calendar year. Accrued but unused vacation time that accrues after
December 31, 2011 may not be carried over from year to year. Upon execution of this Agreement, the Company shall pay you $128,423 in full satisfaction of your accrued vacation as of December 31, 2011. 

(f) Fringe Benefits. You will be entitled to participate in the same manner as other senior executives of the Company in
any employee benefit plans which the Company provides or may establish for the benefit of its senior executives generally (including, without limitation, group life, disability, medical, dental and other insurance, 401(k), flexible spending account,
retirement, pension, profit-sharing and similar plans) (collectively, the “Fringe Benefits”), provided that the Fringe Benefits will not include any stock option or similar plans relating to the grant of equity securities of the Company.
The Company will pay you $850 monthly during your employment with the Company to cover the cost of a late model car or truck, and will pay any and all additional business-related costs associated with such car or truck (including, but not limited
to, gasoline, maintenance, repairs and insurance). For so long as you are employed as Chief Executive Officer, the Company will pay an additional $6,000.00 per month to cover the cost of your housing and living expenses in Massachusetts, while you
continue to maintain your primary residence outside of Massachusetts. For so long as you are employed as Chief Executive Officer, until your daughter Margaret’s eighteenth birthday, the Company will also pay up to $10,000 per year in travel and
associated expenses to facilitate visits with your daughter Margaret during the year. If and to the extent any of the fringe benefits described in this Section 3(f), as such may be modified by mutual written agreement from time to time, are
taxable to you as ordinary income, the Company will provide a tax “gross-up,” as described in Section 4(f). 

(g) Life Insurance; Disability Insurance. The Company, at its expense, will purchase life insurance on your life in the
face amount of not less than $1 million with a beneficiary designated by you. The Company will also arrange and pay the premiums associated with short and long-term disability insurance on your behalf with annual benefits in an amount equal to 60%
of your Base Salary. During the time period during which you receive benefits under the short and long-term disability policy(-ies), the Company shall not be obligated to pay your Base Salary. 

  
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 (h) Reimbursement of Expenses. The Company will reimburse you for all ordinary
and reasonable out-of-pocket business expenses that are incurred by you in furtherance of the Company’s business in accordance with the Company’s policies with respect thereto as in effect from time to time, and which are supported by
valid receipts presented to the Company when you seek reimbursement. For so long as you are employed as Chief Executive Officer, the Company will pay directly the annual fee for membership in the Union League of Philadelphia. 

(i) Indemnification. The Company will indemnify you to the extent permitted by its charter and by-laws and by applicable
law, as set forth in the Company’s charter, by-laws and a separate indemnification agreement (provided that you execute such agreement). In connection with the foregoing, you will be covered under any liability insurance policy that protects
other officers of the Company. Such liability insurance shall be approved by the Board and cannot be reduced without your consent. 
 (j) Legal fees. The Company shall pay directly or reasonably reimburse you for all legal fees and related costs incurred or paid by you in connection with the preparation and/or negotiation
of this Agreement (but not for any future amendments or modifications). 
  

	 	4.	Severance Compensation. 

(a) Definition of Accrued Obligations. For purposes of this Agreement, “Accrued Obligations” means (i) the
portion of your Base Salary as has accrued prior to any termination of your employment with the Company and has not yet been paid, (ii) an amount equal to the value of your accrued unused vacation days, (iii) the amount of any annual bonus
earned, accrued and declared but not yet paid and (iv) the amount of any expenses properly incurred by you on behalf of the Company prior to any such termination and not yet reimbursed pursuant to Section 3(h) hereof. 

(b) Death or Disability. If your employment hereunder is terminated as a result of your death or Disability (defined
below): 
 (i) The Company will pay the Accrued Obligations to you (or your estate) promptly following such termination.

 (ii) The Company will continue to pay you (or your estate) an amount equal to the Base Salary at the rate in effect at the
date of such termination in accordance with Section 3(a) of this Agreement for a period of eighteen months commencing on the date of such termination (subject to execution, delivery and not revoking a waiver and release, as described herein).

 For purposes of this Agreement, “Disability” shall mean that you have been unable to perform your duties hereunder
as the result of your incapacity due to physical or mental illness, and such inability, which continues for at least 120 consecutive calendar days or 150 calendar days during any consecutive twelve-month period, if shorter, after its commencement,
is determined to be total and permanent by a physician selected by the Company and its insurers and acceptable to you or to your legal representative (with such agreement on acceptability not to be unreasonably withheld). 

(c) Termination for Cause or in the Absence of a Good Reason. If your employment hereunder is terminated either by the Company for
Cause or by you in the absence of a Good Reason, the Company will pay the Accrued Obligations to you promptly following such termination. 
 (d) Termination without Cause or for a Good Reason. If your employment hereunder is terminated either by the Company without Cause or by you for a Good Reason, the Company will pay the Accrued
Obligations to you promptly following such termination. In addition, provided that you first execute and deliver to the Company, and do not revoke during any applicable revocation period, a full and 

  
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general waiver and release of any and all claims you may have against the Company, its direct and indirect subsidiaries, its current and former officers, directors, stockholders, employees,
agents, representatives, insurers and related persons and parties, and provided that you are not in breach and have not breached this Agreement: 
 (i) The Company will continue to pay you an amount equal to the Base Salary at the rate in effect at such termination in accordance with Section 3(a) of this Agreement for a period of eighteen
(18) months. 
 (ii) The Company will continue to provide you with health insurance (through COBRA, in the Company’s
discretion), subject to applicable law and the terms of the respective policies, until the earlier of: (i) eighteen (18) months from the date of termination; (ii) you commence full-time employment with another company or provide full
time consulting services to another company; or (iii) you are covered by another health insurance plan. 
 (iii) The
Company will pay the target bonus for the then fiscal year, pro rated based on the number of days of such fiscal year that have elapsed as of your termination date, based on a 365 day year. 

(iv) All stock options, restricted stock and other equity awards previously granted to you shall become vested immediately and shall be
exercisable in full in accordance with the applicable stock option, restricted stock or other form of equity agreement and the terms of any applicable stock or equity plan. 
 (e) No Duty to Mitigate. Notwithstanding any other provision of this Agreement, you will have no obligation to mitigate your damages for any breach of this Agreement by the Company or for any
termination of this Agreement, whether by seeking employment or otherwise, provided, however, the amount of any benefit pursuant to §4 (d)(ii) of this Agreement otherwise due to you after the date of such termination pursuant to this Agreement
will be reduced or offset by any payment or benefit that you may receive from any other source. 
 (f) Tax Gross Up. In
the event that either (i) the fringe benefits described in Section 3(f) are taxable to you as ordinary income or (ii) the payments or benefits to you from the Company under this Agreement or any related equity agreement will cause you
to incur liability for excise taxes under Sections 280G of the Code, you will have the option to: (a) reduce or postpone such payments or benefits; or (b) elect to receive a “gross up payment” from the Company in an amount that
is sufficient to cover the both the excise taxes and the taxes imposed on you as a result of the gross up payment itself (the “Gross Up Payment”). In the event that you and the Company disagree on the amount of the Gross Up Payment, the
Company shall engage, at its sole expense, a mutually agreeable tax accounting firm, whose determination of the amount of the Gross Up Payment shall be conclusive and binding on the parties. The Company shall also indemnify you against additional
taxes and penalties that may be imposed on you in the event that a state or federal taxing authority later determines that the Gross Up Payment was insufficient to cover your tax liabilities for the payments and benefits referenced above.

 Notwithstanding the foregoing, in compliance with Section 409A of the Internal Revenue Code of 1986, as amended
(“Section 409A”) (to the extent applicable), and notwithstanding any other provision of the Company’s plans in effect from time to time: 
  

	 	i.	The amount of expenses eligible for reimbursement and the provision of in-kind benefits during any calendar year shall not affect the amount of expenses eligible for
reimbursement or the provision of in-kind benefits in any other calendar year; 

  
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	 	ii.	The reimbursement of an eligible expense shall be made on or before December 31 of the calendar year following the calendar year in which the expense was incurred;

  

	 	iii.	Reimbursement or right to an in-kind benefit shall not be subject to liquidation or exchange for another benefit; and 

 

	 	iv.	Each reimbursement payment or provision of in-kind benefit shall be one of a series of separate payments (and each shall be construed as a separate identified payment)
for purposes of Section 409A. 

 You acknowledge and agree that after the date of termination of your
employment, but prior to payment of any of the severance payments and benefits, you or your estate, as applicable, shall execute a release (as described herein). You understand and agree that the payment of any of the severance payments and benefits
is contingent upon your or your estate’s, as applicable, execution and delivery to the Company of the Release and such Release being effective and not revoked on the sixtieth (60th) day following the date of termination. The severance payments and benefits herein (other than the Accrued
Obligations) shall commence on the sixtieth
(60th) day after your date of termination provided
that the release is effective on such date; provided that the pro rata amount of the target bonus pursuant to Section 4(d)(iii) shall be paid on the sixtieth (60th) day after your date of termination provided that the release is effective on such date. If the release is not
effective on the sixtieth (60th) day after the date
of termination, then you shall not be entitled to any severance payments and benefits and you shall only be entitled to receive the Accrued Obligations through the date of termination, in accordance with the Company’s normal payroll procedures
unless otherwise provided by law. Notwithstanding the foregoing, the Company may immediately terminate any or all severance payments and benefits upon material breach by you of the release or any other agreement or contract with the Company. The
remedy set forth in the proceeding sentence is in addition to all other remedies of the Company available at law and/or in equity and shall not in any way impair or terminate the effectiveness of the release. Your rights to any severance payments
and benefits shall constitute your sole remedy in the event of termination of your employment. For purposes of this Agreement, your termination of employment shall mean your “separation from service” within the meaning of Treasury
Regulation Section 1.409(A)-1(h). 
 Payments to you under Section 4(b) or 4(d) shall be bifurcated into two portions, consisting of
the portion, if any, that includes the maximum amount of the payments that does not constitute “nonqualified deferred compensation” within the meaning of Section 409A, and the portion, if any, that includes the excess of the total
payments that does constitute nonqualified deferred compensation. Payments hereunder shall first be made from the portion that does not consist of nonqualified deferred compensation until such portion is exhausted and then shall be made from the
portion that does constitute nonqualified deferred compensation. Notwithstanding the foregoing, if you are a “specified employee” as defined in Section 409A(a)(3)(B)(i) of the Internal Revenue Code of 1986, as amended, the
commencement of the delivery of the portion that constitutes nonqualified deferred compensation will be delayed to the date that is 6 months and one day after your termination of employment (the “Earliest Payment Date”). Any payments that
are delayed pursuant to the preceding sentence shall be paid pro rata during the period beginning on the Earliest Payment Date and ending on the date that is 6 months following the Earliest Payment Date. The determination of whether, and the extent
to which, any of the payments to be made to you hereunder are nonqualified deferred compensation shall be made after the application of all applicable exclusions under Treasury Reg. § 1.409A-1(b)(9). Any payments that are intended to qualify
for the exclusion for separation pay due to involuntary separation from 

  
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service set forth in Treasury Regulation Section 1.409A- 1 (b)(9)(iii) must be paid no later than the last day of the second taxable year following the taxable year in which you termination
of employment occurs. 
  

	 	5.	Prohibited Competition. 

(a) Certain Acknowledgements and Agreements. 
 (i) We have discussed, and you recognize and acknowledge the competitive and proprietary aspects of the business of the Company. For purposes of this Section 5, the “Company” shall include
any and all direct and indirect subsidiaries of the Company. 
 (ii) You acknowledge that a business will be deemed competitive
with the Company if it performs any of the services or manufactures or sells any of the products provided or offered (or planned to be provided or offered, if you are aware of such planned products) by the Company or if it performs any other
services and/or engages in the production, manufacture, distribution or sale of any product similar to services or products, which services or products were performed, produced, manufactured, distributed or sold by the Company during the period
while you are employed hereunder. 
 (iii) You further acknowledge that, while you are employed hereunder, the Company will
furnish, disclose or make available to you Confidential Information (as defined below) related to the Company’s business and that the Company may provide you with unique and specialized training. You also acknowledge that such Confidential
Information and such training have been developed and will be developed by the Company through the expenditure by the Company of substantial time, effort and money and that all such Confidential Information and training could be used by you to
compete with the Company. 
 (iv) For purposes of this Agreement, “Confidential Information” means confidential and
proprietary information of the Company, whether in written, oral, electronic or other form, including but not limited to, information and facts concerning business plans, customers, future customers, suppliers, licensors, licensees, partners,
investors, affiliates or others, training methods and materials, financial information, sales prospects, client lists, inventions, or any other scientific, technical or trade secrets of the Company or of any third party provided to you or the
Company under a condition of confidentiality, provided that Confidential Information will not include information that is (1) in the public domain other than through any fault or act by you, (2) known to you prior to its disclosure to you
in the course of your employment with the Company or a predecessor or subsidiary, or (3) lawfully disclosed to you by a source other than the Company or a predecessor or subsidiary which source has a legal right to disclose such information.

 (b) Non-Competition; Non-Solicitation. During the period while you are employed hereunder and either: (x) for a
period of eighteen (18) months following the termination of your employment if for any reason you are entitled to receive payment pursuant to §4(b)(ii) or §4(d) of this Agreement, or (y) for a period of twelve (12) months
following the termination of your employment if you are not entitled to payment pursuant to §4(b)(ii) or §4(d) of this Agreement, you will not during any such period, without the prior written consent of the Company: 

(i) For yourself or on behalf of any other person or entity, directly or indirectly, either as principal, partner, stockholder, officer,
director, member, employee, consultant, agent, representative or in any other capacity, own, manage, operate or control, or be concerned, connected or employed by, or otherwise associate in any manner with, engage in, or have a financial interest
in, any business which is directly or indirectly competitive with the business of the Company (each, a “Restricted Activity”) anywhere in the world (the “Restricted Territory”), except that (A) nothing contained herein

  
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will preclude you from purchasing or owning securities of any such business if such securities are publicly traded, and provided that your holdings do not exceed three percent of the issued and
outstanding securities of any class of securities of such business, and (B) nothing contained herein will prevent you from engaging in a Restricted Activity for or with respect to any subsidiary, division or affiliate or unit (each, a
“Unit”) of an entity if that Unit is not engaged in any business which is competitive with the business of the Company, irrespective of whether some other Unit of such entity engages in such competition (as long as you do not engage in a
Restricted Activity for such other Unit); or 
 (ii) Either individually or on behalf of or through any third party, directly or
indirectly, solicit, divert or appropriate or attempt to solicit, divert or appropriate, for the purpose of competing with the Company, any customers or patrons of the Company, or any prospective customers or patrons with respect to which the
Company has developed or made a sales presentation (or similar offering of services); or 
 (iii) Either individually or on
behalf of or through any third party, solicit, entice or persuade or attempt to solicit, entice or persuade any employee of or consultant to the Company to leave the service of the Company. 

(c) Survival of Acknowledgements and Agreements. Your acknowledgements and agreements set forth in this Section 5 will
survive the termination of your employment hereunder for any reason or for no reason. 
 6. Protected Information. You
will at all times, both during the period while you are employed by the Company and after the termination of your employment by the Company for any reason or for no reason, maintain in confidence and will not, without the prior written consent of
the Company, use, except in the course of performance of your duties for the Company or by court order, disclose or give to others any Confidential Information. Upon the termination of your employment hereunder for any reason or for no reason, you
will return to the Company all tangible Confidential Information and copies thereof (regardless how such Confidential Information or copies are maintained) and you will delete and destroy all electronic copies of Confidential Information.

 7. Ownership of Ideas, Copyrights and Patents. 

(a) Property of the Company. All ideas, discoveries, creations, manuscripts and properties, innovations, improvements,
know-how, inventions, designs, developments, apparatus, techniques, methods, biological processes, cell lines, laboratory notebooks and formulae (collectively the “Inventions”), whether patentable, copyrightable or not, which you may
conceive, reduce to practice or develop while you are employed by the Company or using the Company’s property or resources, including any confidential information of the Company, alone or in conjunction with another or others, and whether at
the request or upon the suggestion of the Company or otherwise, will be the sole and exclusive property of the Company, and that you will not publish any of the Inventions without the prior written consent of the Company. You hereby assign to the
Company all of your right, title and interest in and to all of the foregoing. 
 (b) Cooperation. At any time
during your employment with the Company or after the termination of your employment with the Company for any reason or for no reason, you will fully cooperate with the Company and its attorneys and agents in the preparation and filing of all papers
and other documents as may be required to perfect the Company’s rights in and to any of such Inventions, including, but not limited to, joining in any proceeding to obtain letters patent, copyrights, trademarks or other legal rights with
respect to any such Inventions in the United States and in any and all other countries, provided that the Company will bear the expense of such proceedings, and that any 

  
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patent or other legal right so issued to you personally will be assigned by you to the Company or its designee without charge by you. The Company will reimburse you for reasonable expenses
incurred by you in connection with the performance of your obligations under this Section 7. 
 8. Records. Upon
termination of your employment with the Company for any reason or for no reason, you will deliver to the Company any property of the Company which may be in your possession, including products, materials, memoranda, notes, records, reports or other
documents or photocopies of the same. 
 9. Insurance. The Company, in its sole discretion, may apply for and purchase
key person life insurance on your life in an amount determined by the Company with the Company as beneficiary. You will submit to any medical or other examinations and to execute and deliver any applications or other instruments in writing that are
reasonably necessary to effectuate such insurance. 
 10. General. 

(a) Notices. All notices, requests, consents and other communications hereunder will be in writing, will be addressed to
the receiving party’s address set forth above or to such other address as a party may designate by notice hereunder, and will be either (i) delivered by hand, (ii) sent by overnight courier, or (iii) sent by registered or
certified mail, return receipt requested, postage prepaid. All notices, requests, consents and other communications hereunder will be deemed to have been given either (i) if by hand, at the time of the delivery thereof to the receiving party at
the address of such party set forth above, (ii) if sent by overnight courier, on the next business day following the day such notice is delivered to the courier service, or (iii) if sent by registered or certified mail, on the fifth
business day following the day such mailing is made. Notices to the Company shall also be sent to Bradley A. Jacobson, Greenberg Traurig, LLP, One International Place, Boston, MA 02110. Notices to you shall be sent to the most recent address on
record with the Company; copies of Notices to you shall also be sent to Martha J. Zackin, Esq., Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C., One Financial Center, Boston, MA 02111. 

(b) Entire Agreement. This Agreement and the other agreements specifically referred to herein, embodies the entire
agreement and understanding between the parties hereto with respect to the subject matter hereof and supersedes all prior oral or written agreements and understandings relating to the subject matter hereof. No statement, representation, warranty,
covenant or agreement of any kind not expressly set forth in this Agreement will affect, or be used to interpret, change or restrict, the express terms and provisions of this Agreement. 

(c) Modifications and Amendments. The terms and provisions of this Agreement may be modified or amended only by written
agreement executed by the parties hereto. 
 (d) Waivers and Consents. The terms and provisions of this Agreement
may be waived, or consent for the departure therefrom granted, only by written document executed by the party entitled to the benefits of such terms or provisions. No such waiver or consent will be deemed to be or will constitute a waiver or consent
with respect to any other terms or provisions of this Agreement, whether or not similar. Each such waiver or consent will be effective only in the specific instance and for the purpose for which it was given, and will not constitute a continuing
waiver or consent. 
 (e) Assignment. You may not assign your rights and obligations under this Agreement without
the prior written consent of the Company. 

  
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 (f) Benefit. All statements, representations, warranties, covenants and
agreements in this Agreement will be binding on the parties hereto and will inure to the benefit of the respective successors and permitted assigns of each party hereto. Nothing in this Agreement will be construed to create any rights or obligations
except among the parties hereto, and no person or entity will be regarded as a third-party beneficiary of this Agreement. 

(g) Governing Law. This Agreement and the rights and obligations of the parties hereunder will be construed in accordance
with and governed by the law of the Commonwealth of Massachusetts, without giving effect to the conflict of law principles thereof. 
 (h) Severability. The parties intend this Agreement to be enforced as written. However, (i) if any portion or provision of this Agreement is to any extent be declared illegal or
unenforceable by a duly authorized court having jurisdiction, then the remainder of this Agreement, or the application of such portion or provision in circumstances other than those as to which it is so declared illegal or unenforceable, will not be
affected thereby, and each portion and provision of this Agreement will be valid arid enforceable to the fullest extent permitted by law and (ii) if any provision, or part thereof, is held to be unenforceable because of the duration of such
provision, the geographic area covered thereby, or other aspect of the scope of such provision, the court making such determination will have the power to reduce the duration, geographic area of such provision, or other aspect of the scope of such
provision, and/or to delete specific words and phrases (“blue-penciling”), and in its reduced or blue-penciled form, such provision will then be enforceable and will be enforced. 

(i) Headings and Captions. The headings and captions of the various subdivisions of this Agreement are for convenience of
reference only and will in no way modify or affect the meaning or construction of any of the terms or provisions hereof 

(j) No Waiver of Rights, Powers and Remedies. No failure or delay by a party hereto in exercising any right, power or
remedy under this Agreement, and no course of dealing between the parties hereto, will operate as a waiver of any such right, power or remedy of the party. No single or partial exercise of any right, power or remedy under this Agreement by a party
hereto, nor any abandonment or discontinuance of steps to enforce any such right, power or remedy, will preclude such party from any other or further exercise thereof or the exercise of any other right, power or remedy hereunder. The election of any
remedy by a party hereto will not constitute a waiver of the right of such party to pursue other available remedies. No notice to or demand on a party not expressly required under this Agreement will entitle the party receiving such notice or demand
to any other or further notice or demand in similar or other circumstances or constitute a waiver of the rights of the party giving such notice or demand to any other or further action in any circumstances without such notice or demand. 

(k) Counterparts. This Agreement may be executed in two or more counterparts, and by different parties hereto on separate
counterparts, each of which will be deemed an original, but all of which together will constitute one and the same instrument. 

(l) 409A Disclaimer. This Agreement is intended to comply with the provisions of Section 409A and the Agreement shall,
to the extent practicable, be construed in accordance therewith. Terms defined in the Agreement shall have the meanings given such terms under Section 409A if and to the extent required in order to comply with Section 409A. No payments to
be made under this Agreement may be accelerated or deferred except as specifically permitted under Section 409A. In the event that the Agreement shall be deemed not to comply with Section 409A, then neither the Company, the Board nor its
or their designees, agents or representatives shall be liable to you for any excise taxes or additional payments or liabilities for which you may be responsible as a result of such failure or otherwise. 

  
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 If the foregoing accurately sets forth our agreement, please so indicate by signing and returning to us the
enclosed copy of this letter. 
 Very truly yours, 
  

			
	InVivo Therapeutics Holdings Corp.
		
	By:	 	 /s/ Christi M. Pedra

	Christi M. Pedra, GNC Committee Chairperson
	
	Accepted and Approved:
	
	 /s/ Frank Reynolds

	Print Name: Frank Reynolds
	Date: March 5, 2012

 Exhibit A 
 ANNUAL CASH BONUS PLAN FOR EXECUTIVE OFFICERS 
 (attached)InVivo Therapeutics Holdings Corp. Annual Cash Bonus Plan

 Exhibit 10.2 
 INVIVO THERAPEUTICS HOLDINGS CORP. 
 ANNUAL CASH BONUS PLAN

 FOR EXECUTIVE OFFICERS 
 Section 1: Purpose 
 The InVivo Therapeutics Holdings Corp. Annual Cash Bonus Plan for
Executive Officers (the “Plan”) is designed to: 
  

	 	•	 	 Attract and retain highly qualified executives and other personnel by providing competitive annual incentive opportunities.

  

	 	•	 	 Provide performance-based incentives that motivate and reward superior managerial performance. 

Section 2: Definition of Terms 
  

	 	a)	Board means the Board of Directors of the Company. 

  

	 	b)	Committee means the Governance, Nominating and Compensation Committee of the Board. 

 

	 	c)	Participants shall be the persons eligible to participate in the Plan, consisting of the Corporation’s “Executive Officers” (as defined under Rule
3b-7 under the Securities Exchange Act of 1934, as amended) and other named participants, as determined by the Committee from time to time. As of the effective date of the Plan, the sole Participant is the President & Chief Executive
Officer. 

 Section 3: Plan Administration 
 The Committee shall have sole and complete discretion to administer and interpret the Plan with respect to the Participants. The decisions of the Committee concerning administration and interpretation of
the Plan shall be final and binding. The Plan shall continue in its current form until and unless action is taken by the Board to modify or terminate the Plan. 
 Section 4: Plan Year 
 Each Plan performance year shall be the Company’s fiscal
year (January 1 – December 31). After the end of the applicable fiscal year, cash incentive payments earned under the Plan shall be determined and approved by the Committee in accordance with the provisions of the Plan. 

Section 5: Performance Targets and Measurement 
 The Plan, which has been approved by the Committee, outlines general performance goals and business criteria upon which each Participant’s performance will be evaluated. The target bonuses and the
specific 

 
performance goals and business criteria with respect to a particular Plan year will be approved each year by the Committee. Performance will be measured against these specific performance goals
and business criteria. Generally, performance will be evaluated based on financial and operational performance goals and business criteria. Financial performance goals and business criteria include, without limitation, targets tied to capital
raising, stock price, trading volume, research coverage and institutional ownership. Operational performance goals and business criteria include, without limitation, targets tied to regulatory filings and approvals, pre-clinical and clinical trials
and related results, publications, intellectual property, joint ventures and joint developments, product development, and manufacturing capabilities. The Committee also has discretion to grant bonuses in excess of the bonus calculated based on the
level of achievement and in excess of the target bonus if it determines that such bonuses are warranted under the circumstances and are in the best interests of the Company and its stockholders. 

Section 6: Earning an Award 
 The
President & CEO annually reviews other Participant’s performance with the Committee and makes recommendations to the Committee with respect to the appropriate payments to be made under the Plan. Based in part on the CEO’s
recommendations and other considerations, the Committee approves the incentive payments (other than the CEO). The Compensation Committee independently evaluates the performance of the CEO and determines and approves the incentive payment earned for
the given performance period. 
 Section 7: Approval 
 The Committee must approve all payments made under the Plan. 
 Section 8: Other Provisions

  

	(a)	Payment Under the Plan. Any applicable earned bonus under the Plan shall be paid within the first seventy-five days after the end of the calendar year in which
the bonus was earned. If the CEO’s employment ends during the calendar year but the CEO has achieved some or all of the performance targets approved by the Committee for such year as of the date of termination, then the CEO will be paid the
amount of bonus represented by such performance targets, with that bonus paid within seventy-five days of the CEO’s separation from the Company, regardless of whether the termination of employment was voluntary or involuntary, subject to the
CEO’s employment agreement with the Company. With respect to all other Participants, whether or not they are entitled to a bonus if their employment ends during the calendar year will be as set forth in the Participant’s employment
agreement, if any, or, if there is no employment agreement, as determined by the Committee at the time such Participant becomes eligible to participate in the Plan. 

 

	(b)	Plan Amendment. The Committee may, at any time and from time to time, amend, alter, suspend, discontinue or terminate the Plan, as it deems necessary or
appropriate to achieve the purposes of the Plan or for other business reasons. 

  

	(c)	No Right to Employment. The existence of this Plan shall not be construed as giving a Participant the right to continued employment or any future right to
participate in the Plan. 

  
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	(d)	Employment for a Portion of a Plan Year. The CEO may recommend and the Committee, at its sole discretion, may permit a Participant to participate in the Plan
during a fiscal year in which the Participant was not employed by the Company for the full fiscal year. Such participation may be on a pro rata basis or on such other basis as the Committee determines. 

 

	(e)	Unfunded Plan. The Plan shall be unfunded and shall not create (or be construed to create) a trust or separate fund(s). Likewise, the Plan shall not establish
any fiduciary relationship between the Company and any other Participant or other person. To the extent that any person holds any rights by virtue being a Participant under the Plan, such right shall be no greater than the right of an unsecured
general creditor of the Company. 

  

	(f)	Successors and Assignees. The Plan shall be binding on all successors and assignees of a Participant, including, without limitation, the estate of such
Participant and the executor, administrator or trustee of such estate, or any receiver or trustee in bankruptcy or representative of the Participant’s creditors. 

 

	(g)	Governing Law. The validity, construction and effect to the Plan and any actions taken under the Plan shall be determined in accordance with applicable laws of
the Commonwealth of Massachusetts. 

  
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