Document:

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                                                              Exhibit 10.8

                              EMPLOYMENT AGREEMENT

         THIS EMPLOYMENT AGREEMENT (the "Agreement") is made effective as of
March 3, 2000 (the "Effective Date"), between AUTOLOGOUS WOUND THERAPY, INC., a
Delaware corporation (the "Company"), and DAVID C. DEMAREST ("Executive").

     WHEREAS, the Company desires to employ Executive on the terms and
conditions hereinafter set forth;

     WHEREAS, the Company recognizes that Executive's employment is critical to
the growth and success of the Company and therefore desires to assure the
Company of Executive's continued employment; and

     WHEREAS, based on the foregoing, the Company and Executive wish to enter
into this agreement to come into force as of the Effective Date.

     NOW, THEREFORE, in consideration of the promises and the mutual covenants
and agreements herein contained, the Company and Executive hereby agree as
follows:

                             ARTICLE 1. EMPLOYMENT

A. EMPLOYMENT AND DUTIES. The Company shall employ Executive for the Term (as
hereinafter defined) as Vice President, Secretary and General Counsel, to
perform such duties as he shall reasonably be directed by the President to
perform. Executive hereby accepts such employment and agrees to render such
services on behalf of the Company. Executive shall perform his duties and carry
out his responsibilities hereunder in a diligent manner, and shall devote his
exclusive and full working time, attention and effort to the affairs of the
Company, shall use all reasonable efforts to promote the interests of the
Company and shall be just and faithful in the performance of his duties and in
carrying out his responsibilities.

B. LOCATION. The principal location for performance of Executive's services
hereunder shall be at the Company's executive offices, which are to be
re-located to north suburban Chicago, Illinois, subject to reasonable travel
requirements during the course of performing such services.

                          ARTICLE 2. EMPLOYMENT TERM

     The term of Executive's employment hereunder (the "Term") shall be deemed
to commence on the Effective Date and shall end on December 31, 2001, unless
sooner terminated in accordance with the terms of this Agreement; provided,
however, that the Term shall be automatically renewed and extended for
additional and successive Terms of two (2) years each at the end of each Term
(and any subsequent renewal Term thereof) unless either party gives Notice of
Termination (as hereinafter defined) to the other party no later than ninety
(90) days before the expiry of the then-current Term.

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                     ARTICLE 3. COMPENSATION AND BENEFITS

         In consideration for performing services on behalf of the Company, the
Executive shall receive the following compensation and benefits:

A.   CASH COMPENSATION.

     i. BASE SALARY. The Company shall pay Executive an annual salary of One
     Hundred and Fifty Thousand Dollars ($150,000), payable in bi-weekly
     installments, in arrears (the "Base Salary"). The Base Salary shall be
     reviewed annually by the Company's Board of Directors and may be
     increased, but not decreased (unless mutually agreed upon by Executive and
     the Company).

     ii. BONUS AND INCENTIVE PLANS. The Company shall establish, and Executive
     shall be entitled to participate in, Executive Bonus Compensation and
     Long-Term Incentive Programs, which shall be substantially in accordance
     with the summary points contained in Part A of Appendix I, attached hereto
     and made part hereof.

     iii. PARTICIPATION IN BENEFIT PLANS. The Company shall establish, and
     Executive shall be entitled to participate in (and to the extent that
     Executive's position, title, tenure, salary, age, health, and other
     qualifications make him eligible to participate in), employee benefit
     plans or programs, which shall be substantially in accordance with the
     summary points contained in Part B of Appendix I. The Company does not
     guarantee the continuance of any particular employee benefit plan or
     program during the Term and Executive's participation in any such plans or
     programs shall be subject to all terms, provisions, rules, and regulations
     applicable thereto. Executive will be entitled to twenty (20) days of
     vacation per year, to be used in accordance with the Company's vacation
     policy for senior executives as may be in force from time to time. During
     the existence of a Benefit Period, if any, (as hereinafter defined), the
     Company will arrange to provide Executive with welfare benefits (including
     life and health insurance benefits) of substantially similar design and
     cost to Executive as the welfare benefits and other employee benefits
     available to Executive prior to Executive's or the Company's, as the case
     may be, receipt of Notice of Termination (as hereinafter defined). In the
     event that Executive shall obtain full-time employment providing
     comparable welfare benefits during the Benefit Period, such benefits as
     otherwise receivable hereunder by Executive shall be discontinued.

     iv. EXPENSES. The Company will pay or reimburse Executive for all
     reasonable and necessary out-of-pocket expenses incurred by him in the
     performance of his duties under this Agreement, including first class air
     travel and reasonable capital and operating expenses for an office in
     Executive's home. Executive shall keep detailed and accurate records of
     expenses incurred in connection with the performance of his duties
     hereunder

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     and reimbursement therefor shall be in accordance with policies and
     procedures to be established from time to time by the Company's Board of
     Directors.

B.   STOCK WARRANTS. As a special incentive to obtain the services of
     Executive, Company hereby grants Executive the option to purchase two
     hundred thousand (200,000) shares of the common stock of the Company at
     $7.00 per share at any time, under either periodic or accelerated exercise
     terms as described below.

     i. PERIODIC EXERCISE RIGHTS. Executive's option to purchase shares shall
     vest and become fully and freely exercisable with respect to the first
     sixty-seven thousand (67,000) shares on December 31, 2000; with respect to
     the next sixty-seven thousand (67,000) shares on December 31, 2001, and
     with respect to the final sixty-six thousand (66,000) shares on December
     31, 2002; subject, however, to the provisions of Sub-section (iii), of
     this Section (B):

     ii. ACCELERATED EXERCISE RIGHTS. Notwithstanding periodic exercise rights,
     all of Executive's options that are not already exercisable in accordance
     with Sub-section 3(B)(i) shall become immediately exercisable at such time
     that the common stock of the Company trades at or above 37 and 5/8ths
     dollars per share (the "Target Price") as quoted on the securities
     exchange where the Company stock is currently being traded and during
     either of the two periods, chosen at the option of the Executive:

          a. the closing price for the stock is at or above the Target Price
          for fifteen (15) consecutive trading days; or

          b. the closing price for the stock is at or above the Target Price
          for twenty (20) out of any thirty (30) consecutive trading days.

     The determination of the Target Price during either of such periods shall
     be conclusive as reported by any independent financial reporting service,
     such as Reuters or Bloomberg Financial Markets.

     iii. POST-TERMINATION EXERCISE RIGHTS. Notwithstanding any of the
     foregoing, Executive shall have the right to exercise options to purchase
     any stock warrants or other stock grants given by the Company in
     accordance with the following:

          (a) if Executive's employment is terminated for Cause (as defined in
          Article 4(A)(ii), hereunder), or in the event that Executive
          voluntarily resigns his employment with the Company, vesting of all
          options shall cease immediately upon the effective date of
          termination or resignation;

          (b) if Executive's employment is terminated by reason of Death or
          Disability (as defined in Article 4(B) hereunder), Executive's legal
          representatives, conservators, heirs or assigns shall have the right
          to exercise all such options until

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          such options expire in accordance with the option plan under which
          such options were granted. The rights granted under this
          Sub-paragraph (iii)(b) shall apply whether or not the option was
          vested at the time of Death or Disability; provided, however, tha
          Executive was employed by the Company for at least twelve (12) months
          after the grant of any option; or

          (c) if Executive's employment is terminated for any reason other than
          Death or Disability, or in the event that Executive voluntarily
          resigns, then Executive shall have the right to exercise all options
          that have already vested as of the effective date of termination or
          resignation (or that become vested by reason of termination or
          resignation) during a period of ninety (90) days following the
          effective date of termination or resignation.

     iv. ISSUANCE OF REGISTERED SHARES. The Company hereby guarantees that it
     will issue registered common stock (the term "registered" as defined in
     the Securities and Exchange Act of 1934) to the Executive pursuant to the
     exercise of his options under Sub-sections (i) - (iii) of this Section
     3(B). In the event that the Company does not have sufficient quantities of
     registered shares available to satisfy this obligation, it shall
     immediately take all steps necessary to issue a registration statement and
     to make sufficient registered shares available in satisfaction of this
     Sub-section (iv).

     v. DILUTION. In the event that the Company issues new or additional equity
     securities, debt securities convertible into equity, declares a stock
     dividend, stock split, grants stock rights, or performs any other action
     that would reasonably be expected to reduce the value of the warrants, the
     Company shall immediately reduce the purchase price, increase number of
     the warrants, or both, so that value of the warrants granted to Executive
     remains unchanged.

     vi. EXPIRATION DATE. The options to purchase shares shall expire ten (10)
     years from the date each option becomes exercisable.

                     ARTICLE 4. TERMINATION OF EMPLOYMENT

A.   DEFINITIONS. The following terms shall have the definitions as described
     in this Section A:

     i.   "Benefit Period" shall mean:

          a.   the twenty-four (24) month period commencing on the Date of
               Termination which occurs in connection with a termination of
               employment described in the first sentence of Section 4(E)(i);
               or

          b.   the period consisting of the remainder, if any, of the then
               current Term in which occurs a termination of employment
               described in the first sentence of Section 4(E)(ii), plus the
               immediately succeeding twenty-four (24) month period.

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     ii. "Cause" shall mean any of the following:

          a. any act or failure to act (or series or combination thereof) by
          Executive done with the intent to harm in any material respect to the
          interests of the Company;

          b. the commission by Executive of a felony involving moral turpitude;

          c. the perpetration by Executive of a dishonest act or common law
          fraud against the Company or any subsidiary thereof;

          d. a grossly negligent act or failure to act (or series or
          combination thereof) by Executive detrimental in any material respect
          to the interests of the Company;

          e. the material breach by Executive of his agreements or obligations
          under this Agreement; or

          f. the continued refusal to follow the directives of the President or
          Board of Directors that are consistent with Executive's duties and
          responsibilities identified in Section 1(A) hereof.

     iii. A "Change of Control" shall mean any of the following:

          a. a sale of all or substantially all of the assets of the Company;

          b. the acquisition of more than eighty percent (80%) of the Common
          Stock of the Company (with all classes or series thereof treated as a
          single class) by any person or group of persons, except a Permitted
          Shareholder (as hereinafter defined), acting in concert. A "Permitted
          Shareholder" means a holder, as of the date the Stock Option Plan was
          adopted by the Company, of Common Stock;

          c. a reorganization of the Company wherein the holders of Common
          Stock of the Company receive stock in another company, a merger of
          the Company with another company wherein there is an eighty percent
          (80%) or greater change in the ownership of the Common Stock of the
          Company as a result of such merger, or any other transaction in which
          the Company (other than as the parent corporation) is consolidated
          for federal income tax purposes or is eligible to be consolidated for
          federal income tax purposes with another corporation;

          d. in the event that the Common Stock is traded on an established
          securities market, a public announcement that any person has acquired
          or has the right to acquire beneficial ownership of fifty-one percent
          (51%) or more of the then-outstanding Common Stock and for this
          purpose the terms "person" and

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          "beneficial ownership" shall have the meanings provided in Section
          13(d) of the Securities and Exchange Act of 1934 or related rules
          promulgated by the Securities and Exchange Commission, or the
          commencement of or public announcement of an intention to make a
          tender offer or exchange offer for fifty-one percent (51%) or more of
          the then outstanding Common Stock;

          e. a majority of the Board of Directors is not comprised of
          Continuing Directors. A "Continuing Director" means a director
          recommended by the Board of Directors of the Company for election as
          a director of the Company by the stockholders; or

          f. the Board of Directors of the Company, in its sole and absolute
          discretion, determines that there has been a sufficient change in the
          share ownership of the Company to constitute a change of effective
          ownership or control of the Company.

     iv. "Good Reason" shall mean the occurrence of any one or more of the
     following events during the Term:

          a. the assignment to Executive of any duties inconsistent in any
          respect with Executive's position (including status, offices, title,
          and reporting requirements), authority, duties or other
          responsibilities or any other action of the Company that results in a
          diminishment in such position, authority, duties or responsibilities,
          other than an insubstantial and inadvertent action that is remedied
          by the Company promptly after receipt of notice thereof given by
          Executive;

          b. a reduction by the Company in Executive's Base Salary as in effect
          on the Effective Date and as the same shall be increased from time to
          time hereafter;

          c. the Company's requiring Executive to be based at a location in
          excess of fifteen (15) miles from the location of Executive's
          principal residence without the consent of Executive;

          d. the failure by the Company to: (a) continue in effect any material
          compensation or benefit plan, program, policy or practice in which
          Executive was participating during the Term of his employment or at
          the time of a Change of Control; or (b) provide Executive with
          compensation and benefits at least equal (in terms of benefit levels
          and/or reward opportunities) to those provided for under each
          employee benefit plan, program, policy and practice as in effect
          immediately prior to a Change of Control (or as in effect following
          the Change of Control, if greater);

          e. the failure of the Company to obtain a satisfactory agreement from
          any successor to the Company to assume and agree to perform this
          Agreement; or

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          f. any purported termination by the Company of Executive's employment
          that is not effected pursuant to a Notice of Termination (as defined
          below).

     v. "Date of Termination" shall mean the date specified in the Notice of
     Termination (as hereinafter defined) (except in the case of Executive's
     death, in which case Date of Termination shall be the date of death);
     provided, however, that if Executive's employment is terminated by the
     Company other than for Cause, the date specified in the Notice of
     Termination shall be at least thirty (30) days from the date the Notice of
     Termination is given to Executive and if Executive's employment is
     terminated by Executive for Good Reason, the date specified in the Notice
     of Termination shall not be more than sixty (60) days from the date the
     Notice of Termination is given to the Company.

     vi. "Notice of Termination" shall mean a written notice either from the
     Company to Executive, or Executive to the Company, that indicates Section
     2 or the specific provision of Section 4 of this Agreement relied upon as
     the reason for such termination or non-renewal, the Date of Termination,
     and, in reasonable detail, the facts and circumstances claimed to provide
     a basis for termination or non-renewal pursuant to Section 2 or this
     Section 4 of this Agreement.

B. TERMINATION UPON DEATH OR DISABILITY. This Agreement, and Executive's
employment hereunder, shall terminate automatically and without the necessity
of any action on the part of the Company upon the death of Executive. In
addition, if at any time during the Term Executive shall become physically or
mentally disabled, whether totally or partially, so that he is unable
substantially to perform his duties and services hereunder for:

     i. a period of six (6) consecutive months; or

     ii. for shorter periods aggregating six (6) months during any twelve (12)
     month period;

then, the Company may at any time after the last day of the sixth consecutive
month of disability or the day on which the shorter periods of disability shall
have equaled an aggregate of six (6) months, by written notice to Executive
(but before Executive has recovered from such disability), terminate this
Agreement and Executive's employment hereunder.

C. COMPANY'S AND EXECUTIVE'S RIGHT TO TERMINATE PRIOR TO CHANGE OF CONTROL.
Prior to a Change of Control, this Agreement and Executive's employment
hereunder may be terminated at any time by the Company, with or without Cause,
upon thirty (30) days prior written notice to Executive, and by Executive, at
any time, upon thirty (30) days prior written notice to the Company. Any
termination of Executive's employment by the Company without Cause prior to a
Change of Control that occurs at the request or insistence of any person (other
than the

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Company) relating to such Change of Control shall be deemed to have
occurred after the Change of Control for the purposes of this Agreement.

D. COMPANY'S AND EXECUTIVE'S RIGHT TO TERMINATE FOLLOWING A CHANGE OF CONTROL.
Following a Change of Control, this Agreement and Executive's employment
hereunder may be terminated at any time:

     i. by the Company, with or without Cause, upon thirty (30) days prior
     written notice to Executive, or

     ii. by Executive for Good Reason upon thirty (30) days prior written
     notice to the Company. Executive's right to terminate his employment
     pursuant to this Section 4(D) shall not be affected by incapacity due to
     physical or mental illness. Executive's continued employment following a
     Change of Control shall not constitute consent to, or a waiver of, rights
     with respect to, any circumstance constituting Good Reason hereunder.

E. COMPENSATION UPON TERMINATION.

     i. TERMINATION PRIOR TO CHANGE OF CONTROL. In the event the Company
     terminates (or elects not to renew) this Agreement without Cause, and such
     termination (or non-renewal) without Cause occurs prior to any Change of
     Control, Executive shall be entitled to receive his Base Salary through
     the Date of Termination, the welfare benefits described in Section
     3(A)(iii) for the Benefit Period, and not later than thirty (30) days
     after the Date of Termination, a lump sum severance payment equal to the
     product of two (2) times the sum of Executive's then-current Base Salary
     plus the arithmetic average of payments made to Executive pursuant to the
     Company's Executive Bonus Compensation Program with respect to the three
     (3) fiscal years immediately preceding the fiscal year in which the Date
     of Termination occurs. In addition to the foregoing, to the extent not
     otherwise required under the Company's Stock Option Plan or any award
     agreement with Executive, any unvested stock option awards theretofore
     awarded to Executive shall vest and become exercisable on the Date of
     Termination. In the event this Agreement is terminated (or not renewed)
     for any reason other than by the Company without Cause, and such
     termination (or non-renewal) occurs prior to a Change of Control,
     Executive shall not be entitled to the continuation of any compensation,
     bonuses or benefits provided hereunder, or any other payments following
     the Date of Termination, other than Base Salary earned through such Date
     of Termination.

     ii. TERMINATION FOLLOWING CHANGE OF CONTROL. If this Agreement is
     terminated (or not renewed)

          a. by the Company without Cause; or

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          b. by the Executive for Good Reason during the twelve (12) month
          period immediately following a Change of Control, and such
          termination (or non-renewal) occurs following a Change of Control;

     then, the Executive shall be entitled to receive his full Base Salary
     through the Date of Termination, the welfare benefits described in Section
     3(A)(iii) for the Benefit Period and, not later than thirty (30) days
     after the Date of Termination, a lump sum severance payment equal to the
     sum of the Base Salary which would otherwise have been payable for the
     remainder (if any) of the then current Term, plus an amount equal the
     product of two (2) times the sum of Executive's then current annual Base
     Salary plus the arithmetic average of payments made to Executive pursuant
     to the Company's Executive Bonus Compensation Program with respect to the
     three (3) fiscal years immediately preceding the fiscal year in which the
     Date of Termination occurs.

     In addition to the foregoing, to the extent not otherwise required under
     the Company's Stock Option Plan or any other award agreement with
     Executive, any unvested stock option awards theretofore awarded to
     Executive shall vest and become immediately exercisable in full. In the
     event this Agreement is terminated (or not renewed) for any reason other
     than by the Company without Cause, or by Executive for Good Reason, and
     such termination (or non-renewal) occurs following a Change of Control,
     Executive shall not be entitled to the continuation of any compensation,
     bonuses or benefits provided hereunder, or any other payments following
     the Date of Termination, other than Base Salary earned through the Date of
     Termination.

     iii. At Executive's option to be exercised by written notice to the
     Company, the severance benefits payable under this Section 4(E) shall be
     paid in accordance with the Company's normal payroll procedures in
     installments over a twenty-four (24) month period corresponding to the
     amount of the payments instead of in a lump sum.

     iv. Anything to the contrary contained herein notwithstanding, as a
     condition to Executive receiving severance benefits to be paid pursuant to
     this Section 4(E), Executive shall execute and deliver to the Company a
     general release in form and substance reasonably satisfactory to the
     Company releasing the Company and its officers, directors, employees and
     agents from all liabilities, claims and obligations of any nature
     whatsoever, excepting only the Company's obligations under this Agreement,
     under any Stock Option Award Agreements, and under any other employee
     benefit plans or programs in which Executive participates under Section 3
     hereof, subject to all terms and conditions of such plans or programs and
     this Agreement.

                        ARTICLE 5. EMPLOYMENT COVENANTS

A. TRADE SECRETS AND CONFIDENTIAL INFORMATION. Executive agrees that he shall,
during the course of his employment and for a period of five (5) years
thereafter, hold inviolate and keep secret all documents, materials, knowledge
or other confidential business or technical

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information of any nature whatsoever disclosed to or developed by him or to
which he had access as a result of his employment (hereinafter referred to as
"Confidential Information"). Such Confidential Information shall include
technical and business information, including, but not limited to, inventions,
research and development, engineering, products, designs, manufacture, methods,
systems, improvements, trade secrets, formulas, processes, marketing,
merchandising, selling, licensing, servicing, customer lists, records or
financial information, manuals or Company strategy concerning its business,
strategy or policies. Executive agrees that all Confidential Information shall
remain the sole and absolute property of the Company. During the course of his
employment, Executive shall not use, disclose, disseminate, publish, reproduce
or otherwise make available such Confidential Information to any person, firm,
corporation or other entity, except for the purpose of conducting business on
behalf of the Company. Following the Term, Executive shall not use, disclose,
disseminate, publish, reproduce, or otherwise make available such Confidential
Information to any person, firm, corporation, or other entity. Upon termination
of his employment with the Company, Executive will leave with or deliver to the
Company all records and any compositions, articles, devices, equipment and
other items which disclose or embody Confidential Information including all
copies or specimens thereof, whether prepared by his or by others. The
foregoing restrictions on disclosure of Confidential Information shall apply so
long as the information has not properly come into the public domain through no
action of Executive.

B. TRANSFER OF INVENTIONS. Executive, for himself and his heirs and
representatives, will promptly communicate and disclose to the Company, and
upon request will, without additional compensation, execute all papers
reasonably necessary to assign to the Company or the Company's nominees, free
of encumbrance or restrictions, all inventions, discoveries, improvements,
whether patentable or not, conceived or originated by Executive solely or
jointly with others, at the Company's expense or at the Company's facilities,
or at the Company's request, or in the course of his employment, or based on
knowledge or information obtained through his employment during the Term. All
such assignments shall include the patent rights in this and all foreign
countries. Notwithstanding the foregoing, this Section 5(B) shall not apply to
any invention for which no equipment, supplies, facilities or trade secret
information of the Company was used and which was developed entirely on
Executive's own time; and

     i. that does not relate:

          a. directly to the business of the Company, or

          b. to the Company's actual or demonstrably anticipated research or
          development; or

     ii. that does not result from any work performed by Executive for the
     Company.

C. EXCLUSIVITY OF EMPLOYMENT. During the Term, Executive shall not directly or
indirectly engage in any activity competitive with or adverse to the Company's
business or welfare or render a material level of services of a business,
professional or commercial nature to any other

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person or firm, whether for compensation or otherwise, except for serving as a
director of another firm.

D. COVENANT NOT TO COMPETE. Executive agrees to be bound and abide by the
following covenants not to compete:

     i. TERM AND SCOPE. During his employment with the Company and for a period
     of two (2) years after the Term, Executive will not render to any
     Conflicting Organization (as hereinafter defined), services, directly or
     indirectly, anywhere in the world in connection with any Conflicting
     Product, except that Executive may accept employment with a large
     Conflicting Organization whose business is diversified (and which has
     separate and distinct divisions) if Executive first certifies to the Board
     of Directors in writing that he has provided a copy of Section 5 of this
     Agreement to such prospective employer, that such prospective employer is
     a separate and distinct division of the Conflicting Organization and that
     Executive will not render services directly or indirectly in respect of
     any Conflicting Product (as hereinafter defined). Such two-year time
     period shall be tolled during any period that Executive is engaged in
     activity in violation of this covenant.

     ii. JUDICIAL ACTION. Executive and the Company agree that, if the period
     of time or the scope of the restrictive covenant not to compete contained
     in this Section 5(D) shall be adjudged unreasonable in any court
     proceeding, then the period of time and/or scope shall be reduced
     accordingly, so that this covenant may be enforced in such scope and
     during such period of time as is judged by the court to be reasonable. In
     the event of a breach or violation of this Section 5(D) by Executive, the
     parties agree than in addition to all other remedies, the Company shall be
     entitled to equitable relief for specific performance, and Executive
     hereby agrees and acknowledges that the Company has no adequate remedy at
     law for the breach of the covenants contained herein.

     iii. DEFINITIONS. For purposes of the covenants contained in this Section
     5(D), the following terms shall have the following meanings:

          a. "Conflicting Product" means any product, method or process, system
          or service of any person or organization other than the Company, in
          existence or under development at the time Executive's employment
          with the Company terminates, that is the same as or substantially or
          directly competes with a product, method or process, system or
          service of or provided by the Company or any of its affiliates or
          about which Executive acquires Confidential Information.

          b. "Conflicting Organization" means any person or organization which
          is engaged in or about to become engaged in, research on or
          development, production, marketing, licensing, selling or servicing
          of a Conflicting Product.

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     iv. DISCLOSURE TO PROSPECTIVE EMPLOYERS. Executive will disclose to any
     prospective employer, prior to accepting employment, the existence of
     Section 5 of this Agreement. The obligation imposed by this Section 5(D)
     shall terminate two (2) years after termination of Executive's employment
     with the Company; provided, however, the running of such two-year period
     shall be tolled to the extent the covenant not to compete contained in
     Section 5(D) hereof is tolled.

                           ARTICLE 6. MISCELLANEOUS

A. NOTICES. Any notice required or permitted to be delivered hereunder shall be
in writing and shall be deemed to be delivered on the earlier of:

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     i. the date received; or

     ii. the date of delivery, refusal or non-delivery indicated on the return
     receipt, if deposited in a United States Postal Service depository,
     postage prepaid, sent registered or certified mail, return receipt
     requested, addressed to the party to receive the same at the address of
     such party set forth below:

         If to the Company:               If to the Executive:

         Autologous Wound Therapy, Inc.   David C. Demarest
         1523 Bowman Road, Suite A        c/o Michael J. Caywood, Esq.
         Little Rock, Arkansas            Dresser, Dresser, Gilbert & Haas, PC
         72211  USA                       112 South Monroe Street
                                          Sturgis, Michigan
                                          49091  USA

     A Party may change its address from time to time by Notice addressed to
the other Party.

B. HEADINGS. The headings of the articles and sections of this Agreement are
inserted for convenience only and shall not be deemed a part of or affect the
construction or interpretation of any provision hereof.

C. MODIFICATIONS & WAIVER. No modification of any provision of this Agreement
or waiver of any right or remedy herein provided shall be effective for any
purpose unless specifically set forth in a writing signed by the party to be
bound thereby. No waiver of any right or remedy in respect of any occurrence or
event on one occasion shall be deemed a waiver of such right or remedy in
respect of such occurrence or event on any other occasion.

D. ENTIRE AGREEMENT. This Agreement contains the entire agreement of the
parties with respect to the subject matter hereof and supersedes all other
agreements; oral or written, heretofore made with respect thereto.

E. SEVERABILITY. Any provision of this Agreement prohibited by or unlawful or
unenforceable under any applicable law of any jurisdiction shall as to such
jurisdiction be ineffective without affecting any other provision hereof. To
the full extent, however, that the provisions of such applicable law may be
waived, they are hereby waived, to the end that this Employment Agreement be
deemed to be a valid and binding agreement enforceable in accordance with its
terms.

F. GOVERNING LAW AND JURISDICTION. This Agreement shall be deemed to have been
entered into by the parties in the State of Illinois and shall be continued and
enforced in accordance with the laws of that State. Any disputes arising under
the terms and conditions of this Agreement shall be resolved in a court of
competent jurisdiction of that State and the parties hereto irrevocably submit
to such jurisdiction.

                                    Page 13

<PAGE>

G. ASSIGNMENTS. The Company shall have the right to assign this Agreement and
to delegate all rights, duties and obligations hereunder to any entity that
controls the Company, that the Company controls or that may be the result of
the merger, consolidation, acquisition or reorganization of the Company and
another entity. Executive agrees that this Agreement is personal to him and his
rights and interest hereunder may not be assigned, nor may his obligations and
duties hereunder be delegated (except as to delegation in the normal course of
operation of the Company), and any attempted assignment or delegation in
violation of this provision shall be void. Notwithstanding any of the
foregoing, all of Executive's rights and interest hereunder shall be assignable
to Executive's legal representatives, executors or conservators in the event of
Executive's Death or Disability.

H. ATTORNEY FEES. In the event of litigation between the parties, to enforce
their respective rights under this Agreement, the prevailing party shall be
entitled to receive from the non-prevailing party reimbursement of the
prevailing party's reasonable attorney's fees and costs at all levels of trial
and appeal.

     IN WITNESS WHEREOF, the parties have executed this Agreement as of the
Effective Date.

         Executive                        Autologous Wound Therapy, Inc.

         /s/ David C. Demarest            By: /s/ Dennis G. Hendren
         -----------------------             ------------------------
         David C. Demarest
                                              Title:  President/CEO

                                    Page 14
<PAGE>

                                   APPENDIX I

                       Part A - Bonus and Incentive Plans

1.   ANNUAL BONUS. In addition to Executive's Base Salary, the Company shall
     pay to the Executive an annual bonus in an initial amount of Seventy-Five
     Thousand Dollars ($75,000). The bonus shall be payable depending on the
     achievement of the Executive and the Company of a specified list of
     performance and payment criteria to be agreed to between the Executive and
     the Company and approved by the Company's Board of Directors. In
     accordance with the Executive's annual salary review, the Executive's
     annual bonus shall be reviewed and increased by the Company's Board of
     Directors as may be appropriate.

2.   LONG TERM INCENTIVE PROGRAM. During the Term of Executive's employment by
     the Company, Executive shall be entitled to participate in the Company's
     Executive Long Term Incentive Program which will be established by the
     Company's Board of Director's in accordance with a strategic plan
     developed for the Company and on appropriate terms and conditions.

                  Part B - Employee Benefit Plans and Programs

1.   INSURANCE PROGRAM. The Company shall establish for the benefit of the
     Executive an insurance program, which shall include, among other things,
     life, health, dental and long-term disability coverage. Such insurance
     program shall be no less competitive than similar benefit programs that
     are established for other health care companies or comparable industries.

2.   PENSION OR PROFIT-SHARING PROGRAMS. In addition to the insurance program,
     the Company shall establish a suitable pension, (401(k)) or other profit
     sharing program, which shall be no less competitive than similar pension
     or profit-sharing programs that are established for other health care
     companies or comparable industries.

                                    Page 15<PAGE>

                                                              Exhibit 10.9

                     * * * * * * * * * * * * * * * * * * * *

                                      Lease

                               THREE PARKWAY NORTH

                     * * * * * * * * * * * * * * * * * * * *

                                     Between

                                 CYTOMEDIX, INC.
                                    (Tenant)

                                       and

                         CARRAMERICA REALTY CORPORATION
                                   (Landlord)

<PAGE>

                                      Lease
                                                                       Page
                                                                       ----

1.       LEASE AGREEMENT................................................. 2

2.       RENT............................................................ 2
         A.      Types of Rent........................................... 2
                 (1)      Base Rent...................................... 2
                 (2)      Additional Rent................................ 2
                 (3)      Rent........................................... 2
         B.      Definitions............................................. 2
                 (1)      Lease Year..................................... 2
                 (2)      Fiscal Year.................................... 3
         C.      Computation of Base Rent and Rent Adjustments........... 3
                 (1)      Prorations..................................... 3
                 (2)      Default Interest............................... 3
                 (3)      Rent Adjustments............................... 3
                 (4)      Miscellaneous.................................. 3

3.       PREPARATION AND CONDITION OF PREMISES; POSSESSION AND
         SURRENDER OF PREMISES .......................................... 3
         A.      Condition of Premises................................... 3
         B.      Tenant's Possession..................................... 3
         C.      Maintenance............................................. 3

4.       PROJECT SERVICES................................................ 4
         A.      Heating and Air Conditioning............................ 4
         B.      Elevators............................................... 4
         C.      Electricity............................................. 4
         D.      Water................................................... 4
         E.      Janitorial Service...................................... 4
         F.      Interruption of Services................................ 4

5.       ALTERATIONS AND REPAIRS......................................... 5
         A.      Landlord's Consent and Conditions....................... 5
         B.      Damage to Systems....................................... 6
         C.      No Liens................................................ 6
         D.      Ownership of Improvements............................... 6
         E.      Removal at Termination.................................. 7

6.       USE OF PREMISES................................................. 7

7.       GOVERNMENTAL REQUIREMENTS AND BUILDING RULES.................... 7

                                       i

<PAGE>

                                                                         Page
                                                                         ----

8.       WAIVER OF CLAIMS; INDEMNIFICATION; INSURANCE.....................  8
         A.      Waiver of Claims.........................................  8
         B.      Indemnification..........................................  8
         C.      Tenant's Insurance.......................................  8
         D.      Insurance Certificates................................... 10
         E.      Landlord's Insurance..................................... 10

9.       FIRE AND OTHER CASUALTY.......................................... 10
         A.      Termination.............................................. 10
         B.      Restoration.............................................. 10

10.      EMINENT DOMAIN.  ................................................ 10

11.      RIGHTS RESERVED TO LANDLORD...................................... 11
         A.      Name..................................................... 11
         B.      Signs.................................................... 11
         C.      Window Treatments........................................ 11
         D.      Keys..................................................... 11
         E.      Access................................................... 11
         F.      Preparation for Reoccupancy.............................. 11
         G.      Heavy Articles........................................... 11
         H.      Show Premises............................................ 11
         I.      Relocation of Tenant..................................... 11
         J.      Use of Lockbox........................................... 12
         K.      Repairs and Alterations.................................. 12
         L.      Landlord's Agents........................................ 12
         M.      Building Services........................................ 12
         N.      Other Actions............................................ 12

12.      TENANT'S DEFAULT................................................. 12
         A.      Rent Default............................................. 12
         B.      Assignment/Sublease or Hazardous Substances Default...... 12
         C.      Other Performance Default................................ 13
         D.      Credit Default........................................... 13
         E.      Vacation or Abandonment Default.......................... 13

13.      LANDLORD REMEDIES................................................ 13
         A.      Termination of Lease or Possession....................... 13
         B.      Lease Termination Damages................................ 13
         C.      Possession Termination Damages........................... 14
         D.      Landlord's Remedies Cumulative........................... 14
         E.      WAIVER OF TRIAL BY JURY.................................. 14

                                       ii
<PAGE>
                                                                         Page
                                                                         ----

         F.      Litigation Costs......................................... 14

14.      SURRENDER........................................................ 14

15.      HOLDOVER......................................................... 15

16.      SUBORDINATION TO GROUND LEASES AND MORTGAGES..................... 15
         A.      Subordination............................................ 15
         B.      Termination of Ground Lease or Foreclosure of Mortgage... 15
         C.      Security Deposit......................................... 15
         D.      Notice and Right to Cure................................. 15
         E.      Definitions.............................................. 16

17.      ASSIGNMENT AND SUBLEASE.......................................... 16
         A.      In General............................................... 16
         B.      Landlord's Consent....................................... 16
         C.      Procedure................................................ 17
         D.      Change of Management or Ownership........................ 17
         E.      Excess Payments.......................................... 17
         F.      Recapture................................................ 17

18.      CONVEYANCE BY LANDLORD........................................... 17

19.      ESTOPPEL CERTIFICATE............................................. 17

20.      SECURITY DEPOSIT................................................. 18

21.      FORCE MAJEURE.................................................... 18

22.      TENANT'S PERSONAL PROPERTY AND FIXTURES.......................... 18

23.      NOTICES.......................................................... 18
         A.      Landlord................................................. 19
         B.      Tenant................................................... 19

24.      QUIET POSSESSION................................................. 20

25.      REAL ESTATE BROKER............................................... 20

26.      MISCELLANEOUS.................................................... 20
         A.      Successors and Assigns................................... 20
         B.      Date Payments Are Due.................................... 20

                                      iii

<PAGE>
                                                                         Page
                                                                         ----

         C.      Meaning of "Landlord", "Re-Entry, "including"
                 and "Affiliate".......................................... 20
         D.      Time of the Essence...................................... 20
         E.      No Option................................................ 20
         F.      Severability............................................. 20
         G.      Governing Law............................................ 20
         H.      Lease Modification....................................... 21
         I.      No Oral Modification..................................... 21
         J.      Landlord's Right to Cure................................. 21
         K.      Captions................................................. 21
         L.      Authority................................................ 21
         M.      Landlord's Enforcement of Remedies....................... 21
         N.      Entire Agreement......................................... 21
         O.      Landlord's Title......................................... 21
         P.      Light and Air Rights..................................... 21
         Q.      Singular and Plural...................................... 21
         R.      No Recording by Tenant................................... 21
         S.      Exclusivity.............................................. 22
         T.      No Construction Against Drafting Party................... 22
         U.      Survival................................................. 22
         V.      Rent Not Based on Income................................. 22
         W.      Building Manager and Service Providers................... 22
         X.      Late Charge and Interest on Late Payments................ 22
         Y.      Tenant's Financial Statements............................ 22

27.      UNRELATED BUSINESS INCOME........................................ 22

28.      HAZARDOUS SUBSTANCES............................................. 22

29.      EXCULPATION...................................................... 23

30.      RELOCATION OPTION; TERMINATION OPTION............................ 23

APPENDIX A - PLAN OF THE PREMISES
APPENDIX B - RULES AND REGULATIONS
APPENDIX C - TENANT IMPROVEMENT AGREEMENT
APPENDIX D - MORTGAGES CURRENTLY AFFECTING THE PROJECT
APPENDIX E - COMMENCEMENT DATE CONFIRMATION

                                       iv

<PAGE>

                                      LEASE

         THIS LEASE (the "Lease") is made as of April 19, 2000 between
CarrAmerica Realty Corporation, a Maryland corporation, t/a Parkway North III
(the "Landlord") and Tenant as named in the Schedule below. The term "Project"
means the building (the "Building") known as "Three Parkway North Center" and
the land (the "Land") located at Three Parkway North Boulevard, Deerfield,
Illinois. "Premises" means that part of the Project leased to Tenant described
in the Schedule and outlined on Appendix A.

         The following schedule (the "Schedule") is an integral part of this
Lease. Terms defined in this Schedule shall have the same meaning throughout the
Lease.

                                    SCHEDULE

         1.       TENANT: Cytomedix, Inc.

         2.       PREMISES: A portion of the second (2nd) floor as outlined on
                  Appendix A

         3.       RENTABLE SQUARE FEET OF THE PREMISES: 5,642

         4.       SECURITY DEPOSIT: None

         5.       TENANT'S REAL ESTATE BROKER FOR THIS LEASE: Trammell Crow
                  Company

         6.       LANDLORD'S REAL ESTATE BROKER FOR THIS LEASE: N/A

         7.       TENANT IMPROVEMENTS, IF ANY: See the Tenant Improvement
                  Agreement attached hereto as Appendix C

         8.       COMMENCEMENT DATE: May 7, 2000, but if the Premises are
                  subject to new construction pursuant to Appendix C, then the
                  Completion Date, as defined therein, if it is later; Landlord
                  and Tenant shall execute a Commencement Date Confirmation
                  substantially in the form of Appendix E promptly following the
                  Commencement Date.

         9.       TERMINATION DATE/TERM: May 31, 2003, three (3) years after the
                  Commencement Date, or if the Commencement Date is not the
                  first day of a month, then after the first day of the
                  following month.

         10.      GUARANTOR: None

         11.      BASE RENT: $26.50 per rentable square foot per year (Annual
                  Base Rent = $149,513.00; Monthly Base Rent = $12,459.42)

<PAGE>

         1. LEASE AGREEMENT. On the terms stated in this Lease, Landlord leases
the Premises to Tenant, and Tenant leases the Premises from Landlord, for the
Term beginning on the Commencement Date and ending on the Termination Date
unless extended or sooner terminated pursuant to this Lease.

         2. RENT.

         A. Types of Rent. Tenant shall pay the following Rent in the form of a
check to Landlord at the following address:

                  CarrAmerica Realty Corporation
                  c/o NationsBank of Georgia
                  P.O. Box 277923
                  Atlanta, GA 30384-7923

or by wire transfer as follows:

                  NationsBank, N.A. (South)
                  ABA Number 061-000-052
                  Account Number 325 183 2566

or in such other manner as Landlord may notify Tenant:

                  (1) Base Rent in monthly installments in advance, the first
         twelve (12) monthly installments (aggregating $149,513) payable
         concurrently with the execution of this Lease and thereafter on or
         before the first day of each month of the Term in the amount set forth
         on the Schedule.

                  (2) Additional Rent in the amount of all costs, expenses,
         liabilities, and amounts which Tenant is required to pay under this
         Lease, excluding Base Rent but including any interest for late payment
         of any item of Rent.

                  (3) Rent as used in this Lease means Base Rent and Additional
         Rent. Tenant's agreement to pay Rent is an independent covenant, with
         no right of setoff, deduction or counterclaim of any kind.

         B. Definitions.

                  a. Lease Year. "Lease Year" means each consecutive
         twelve-month period beginning with the Commencement Date, except that
         if the Commencement Date is not the first day of a calendar month, then
         the first Lease Year shall be the period from the Commencement Date
         through the final day of the twelve months after the first day of the

                                       2
<PAGE>

         following month, and each subsequent Lease Year shall be the twelve
         months following the prior Lease Year.

                  b. Fiscal Year. "Fiscal Year" means the calendar year, except
         that the first fiscal year and the last fiscal year of the Term may be
         a partial calendar year.

         C. Computation of Base Rent and Rent Adjustments.

                  a. Prorations. If this Lease begins on a day other than the
         first day of a month, the Base Rent shall be prorated for such partial
         month based on the actual number of days in such month.

                  b. Default Interest. Any sum due from Tenant to Landlord not
         paid when due shall bear interest from the date due until paid at
         eighteen percent (18%) per annum.

                  c. Rent Adjustments. The square footage of the Premises and
         the Building set forth in the Schedule are conclusively deemed to be
         the actual square footage thereof, without regard to any subsequent
         remeasurement of the Premises or the Building.

                  d. Miscellaneous. So long as Tenant is in default of any
         obligation under this Lease, Tenant shall not be entitled to any refund
         of any amount from Landlord.

         3. PREPARATION AND CONDITION OF PREMISES; POSSESSION AND SURRENDER OF
PREMISES.

         A. Condition of Premises. Except to the extent of the Tenant
Improvements item on the Schedule, Landlord is leasing the Premises to Tenant
"as is", without any obligation to alter, remodel, improve, repair or decorate
any part of the Premises. Landlord shall cause the Premises to be completed in
accordance with the Tenant Improvement Agreement attached as Appendix C.

         B. Tenant's Possession. Tenant's taking possession of any portion of
the Premises shall be conclusive evidence that the Premises was in good order,
repair and condition, subject to latent defects in any Initial Improvements
constructed by Landlord (the repair of which shall be the responsibility of
Landlord only if Tenant notifies Landlord of the existence of such defects
within one [1] year from the date of substantial completion of the Initial
Improvements). Except as set forth in this subsection, Landlord shall have no
obligation or liability to Tenant for latent defects. If Landlord authorizes
Tenant to take possession of any part of the Premises prior to the Commencement
Date for purposes of doing business, all terms of this Lease shall apply to such
pre-Term possession, including Base Rent at the rate set forth for the First
Lease Year in the Schedule prorated for any partial month.

         C. Maintenance. Throughout the Term, Tenant shall maintain the Premises
in their condition as of the Completion Date, loss or damage caused by the
elements, ordinary wear, and fire

                                       3
<PAGE>

and other casualty excepted, and at the termination of this Lease, or Tenant's
right to possession, Tenant shall return the Premises to Landlord in broom-clean
condition. To the extent Tenant fails to perform either obligation, Landlord
may, but need not, restore the Premises to such condition and Tenant shall pay
the cost thereof.

         4. PROJECT SERVICES.

         Landlord shall furnish services as follows:

                  A. Heating and Air Conditioning. During the normal business
         hours of 8:00 a.m. to 6:00 p.m., Monday through Friday, and 8:00 a.m.
         to 1:00 p.m. on Saturday, Landlord shall furnish heating and air
         conditioning to provide a comfortable temperature, in Landlord's
         judgment, for normal business operations, except to the extent Tenant
         installs equipment which adversely affects the temperature maintained
         by the air conditioning system. If Tenant installs such equipment,
         Landlord may install supplementary air conditioning units in the
         Premises, and Tenant shall pay to Landlord upon demand as Additional
         Rent the cost of installation, operation and maintenance thereof.

                  Landlord shall furnish heating and air conditioning after
         business hours if Tenant provides Landlord reasonable prior notice, and
         pays Landlord all then current charges for such additional heating or
         air conditioning.

                  B. Elevators. Landlord shall provide passenger elevator
         service during normal business hours to Tenant in common with Landlord
         and all other tenants. Landlord shall provide limited passenger service
         at other times, except in case of an emergency.

                  C. Electricity. All electricity used in the Premises shall be
         supplied by the electricity company through a separate meter and shall
         be paid for by Tenant. Tenant shall pay for the installation of any
         submeter required on any floor of its Premises. Tenant shall not
         install or operate in the Premises any electrically operated equipment
         or other machinery, other than business machines and equipment normally
         employed for general office use which do not require high electricity
         consumption for operation, without obtaining the prior written consent
         of Landlord.

                  D. Water. Landlord shall furnish hot and cold tap water for
         drinking and toilet purposes. Tenant shall pay Landlord for water
         furnished for any other purpose as Additional Rent at rates fixed by
         Landlord. Tenant shall not permit water to be wasted.

                  E. Janitorial Service. Landlord shall furnish janitorial
         service as generally provided to other tenants in the Building.

                  F. Interruption of Services. If any of the Building equipment
         or machinery ceases to function properly for any cause Landlord shall
         use reasonable diligence to repair

                                       4
<PAGE>

         the same promptly. Landlord's inability to furnish, to any extent, the
         Project services set forth in this Section 4, or any cessation thereof
         resulting from any causes, including without limitation any entry for
         repairs pursuant to this Lease, and any renovation, redecoration or
         rehabilitation of any area of the Building shall not render Landlord
         liable for damages to either person or property or for interruption or
         loss to Tenant's business, nor be construed as an eviction of Tenant,
         nor work an abatement of any portion of Rent, nor relieve Tenant from
         fulfillment of any covenant or agreement hereof. However, in the event
         that an interruption of the Project services set forth in this Section
         4 is within Landlord's reasonable control and such interruption causes
         the Premises to be untenantable for a period of at least ten (10)
         consecutive business days, monthly Rent shall thereafter be abated
         proportionately.

         5. ALTERATIONS AND REPAIRS.

         A. Landlord's Consent and Conditions.

Tenant shall not make any improvements or alterations to the Premises (the
"Work") without in each instance submitting plans and specifications for the
Work to Landlord and obtaining Landlord's prior written consent. Tenant shall
pay Landlord's standard charge for review of the plans and all other items
submitted by Tenant. Landlord will be deemed to be acting reasonably in
withholding its consent for any Work which (a) impacts the base structural
components or systems of the Building, (b) impacts any other tenant's premises,
or (c) is visible from outside the Premises.

Tenant shall reimburse Landlord for actual costs incurred for review of the
plans and all other items submitted by Tenant. Tenant shall pay for the cost of
all Work. All Work shall become the property of Landlord upon its installation,
except for Tenant's trade fixtures and for items which Landlord requires Tenant
to remove at Tenant's cost at the termination of the Lease pursuant to Section
3E.

The following requirements shall apply to all Work:

                  a. Prior to commencement, Tenant shall furnish to Landlord
         building permits, certificates of insurance satisfactory to Landlord,
         and, at Landlord's request, security for payment of all costs.

                  b. Tenant shall perform all Work so as to maintain peace and
         harmony among other contractors serving the Project and shall avoid
         interference with other work to be performed or services to be rendered
         in the Project.

                  c. The Work shall be performed in a good and workmanlike
         manner, meeting the standard for construction and quality of materials
         in the Building, and shall comply with all insurance requirements and
         all applicable governmental laws, ordinances and regulations
         ("Governmental Requirements").

                                       5
<PAGE>

                  d. Tenant shall perform all Work so as to minimize or prevent
         disruption to other tenants, and Tenant shall comply with all
         reasonable requests of Landlord in response to complaints from other
         tenants.

                  e. Tenant shall perform all Work in compliance with Landlord's
         "Policies, Rules and Procedures for Construction Projects" in effect at
         the time the Work is performed.

                  f. Tenant shall permit Landlord to supervise all Work.
         Landlord may charge a supervisory fee not to exceed fifteen percent
         (15%) of labor, material, and all other costs of the Work.

                  g. Upon completion, Tenant shall furnish Landlord with
         contractor's affidavits and full and final statutory waivers of liens,
         as-built plans and specifications, and receipted bills covering all
         labor and materials, and all other close-out documentation required in
         Landlord's "Policies, Rules and Procedures for Construction Projects".

         B. Damage to Systems. If Tenant becomes aware that any part of the
mechanical, electrical or other systems in the Premises shall be or have become
damaged, Tenant shall promptly notify Landlord, and Landlord shall repair such
damage. Landlord may also at any reasonable time make any repairs or alterations
which Landlord deems necessary for the safety or protection of the Project, or
which Landlord is required to make by any court or pursuant to any Governmental
Requirement. Tenant shall at its expense make all other repairs necessary to
keep the Premises, and Tenant's fixtures and personal property, in good order,
condition and repair; to the extent Tenant fails to do so, Landlord may make
such repairs itself. The cost of any repairs made by Landlord on account of
Tenant's default, or on account of the mis-use or neglect by Tenant or its
invitees, contractors or agents anywhere in the Project, shall become Additional
Rent payable by Tenant on notice.

         C. No Liens. Tenant has no authority to cause or permit any lien or
encumbrance of any kind to affect Landlord's interest in the Project; any such
lien or encumbrance shall attach to Tenant's interest only. If any mechanic's
lien shall be filed or claim of lien made for work or materials furnished to
Tenant, then Tenant shall at its expense within ten (10) days thereafter either
discharge or contest the lien or claim. If Tenant contests the lien or claim,
then Tenant shall (i) within such ten (10) day period, provide Landlord adequate
security for the lien or claim, (ii) contest the lien or claim in good faith by
appropriate proceedings that operate to stay its enforcement, and (iii) pay
promptly any final adverse judgment entered in any such proceeding. If Tenant
does not comply with these requirements, Landlord may discharge the lien or
claim, and the amount paid, as well as attorney's fees and other expenses
incurred by Landlord, shall become Additional Rent payable by Tenant on demand.

         D. Ownership of Improvements. All Work as defined in this Section 5,
partitions, hardware, equipment, machinery and all other improvements and all
fixtures except trade fixtures, constructed in the Premises by either Landlord
or Tenant, (i) shall become Landlord's property upon

                                       6
<PAGE>

installation without compensation to Tenant, unless Landlord consents otherwise
in writing, and (ii) shall at Landlord's option either (a) be surrendered to
Landlord with the Premises at the termination of the Lease or of Tenant's right
to possession, or (b) be removed in accordance with Subsection 5E below (unless
Landlord at the time it gives its consent to the performance of such
construction expressly waives in writing the right to require such removal);
provided, that Tenant shall not be required to remove the kitchen or lunch room
facilities installed in the Premises by or on behalf of Tenant.

         E. Removal at Termination. Upon the termination of this Lease or
Tenant's right of possession Tenant shall remove from the Project its trade
fixtures, furniture, moveable equipment and other personal property, any
improvements which Landlord elects shall be removed by Tenant pursuant to
Section 5D, and any improvements to any portion of the Project other than the
Premises. Tenant shall repair all damage caused by the installation or removal
of any of the foregoing items. If Tenant does not timely remove such property,
then Tenant shall be conclusively presumed to have, at Landlord's election (i)
conveyed such property to Landlord without compensation or (ii) abandoned such
property, and Landlord may dispose of or store any part thereof in any manner at
Tenant's sole cost, without waiving Landlord's right to claim from Tenant all
expenses arising out of Tenant's failure to remove the property, and without
liability to Tenant or any other person. Landlord shall have no duty to be a
bailee of any such personal property. If Landlord elects abandonment, Tenant
shall pay to Landlord, upon demand, any expenses incurred for disposition.

         6. USE OF PREMISES. Tenant shall use the Premises only for general
office purposes. Tenant shall not allow any use of the Premises which will
negatively affect the cost of coverage of Landlord's insurance on the Project.
Tenant shall not allow any inflammable or explosive liquids or materials to be
kept on the Premises. Tenant shall not allow any use of the Premises which would
cause the value or utility of any part of the Premises to diminish or would
interfere with any other tenant or with the operation of the Project by
Landlord. Tenant shall not permit any nuisance or waste upon the Premises, or
allow any offensive noise or odor in or around the Premises.

         If any governmental authority shall deem the Premises to be a "place of
public accommodation" under the Americans with Disabilities Act or any other
comparable law as a result of Tenant's use, Tenant shall either modify its use
to cause such authority to rescind its designation or be responsible for any
alterations, structural or otherwise, required to be made to the Building or the
Premises under such laws.

         7. GOVERNMENTAL REQUIREMENTS AND BUILDING RULES. Tenant shall comply
with all Governmental Requirements applying to its use of the Premises. Tenant
shall also comply with all reasonable rules established for the Project from
time to time by Landlord. The present rules and regulations are contained in
Appendix B. Failure by another tenant to comply with the rules or failure by
Landlord to enforce them shall not relieve Tenant of its obligation to comply
with the rules or make Landlord responsible to Tenant in any way. Landlord shall
use reasonable efforts to apply the rules and regulations uniformly with respect
to Tenant and tenants in the Building

                                       7
<PAGE>

under leases containing rules and regulations similar to this Lease. In the
event of alterations and repairs performed by Tenant, Tenant shall comply with
the provisions of Section 5 of this Lease and also Landlord's "Policies, Rules
and Procedures for Construction Projects".

         8. WAIVER OF CLAIMS; INDEMNIFICATION; INSURANCE.

         A. Waiver of Claims. To the extent permitted by law, Tenant waives any
claims it may have against Landlord or its officers, directors, employees or
agents for business interruption or damage to property sustained by Tenant as
the result of any act or omission of Landlord.

         To the extent permitted by law, Landlord waives any claims it may have
against Tenant or its officers, directors, employees or agents for loss of rents
(other than Rent) or damage to property sustained by Landlord as the result of
any act or omission of Tenant.

         B. Indemnification. Tenant shall indemnify, defend and hold harmless
Landlord and its officers, directors, employees and agents against any claim by
any third party for injury to any person or damage to or loss of any property
occurring in the Project and arising from the use of the Premises or from any
other act or omission or negligence of Tenant or any of Tenant's employees or
agents. Tenant's obligations under this section shall survive the termination of
this Lease.

         Landlord shall indemnify, defend and hold harmless Tenant and its
officers, directors, employees and agents against any claim by any third party
for damage to person or Premises or from any other act or omission or negligence
of Landlord or any of Landlord's employees or agents. Landlord's obligations
under this section shall survive the termination of this Lease.

         C. Tenant's Insurance. Tenant shall maintain insurance as follows, with
such other terms, coverages and insurers, as Landlord shall reasonably require
from time to time:

                  a. Commercial General Liability Insurance, with (a)
         Contractual Liability including the indemnification provisions
         contained in this Lease, (b) a severability of interest endorsement,
         (c) limits of not less than Two Million Dollars ($2,000,000) combined
         single limit per occurrence and not less than Two Million Dollars
         ($2,000,000) in the aggregate for bodily injury, sickness or death, and
         property damage, and umbrella coverage of not less than Five Million
         Dollars ($5,000,000).

                  b. Property Insurance against "All Risks" of physical loss
         covering the replacement cost of all improvements, fixtures and
         personal property. Tenant waives all rights of subrogation, and
         Tenant's property insurance shall include a waiver of subrogation in
         favor of Landlord.

                  c. Workers' compensation or similar insurance in form and
         amounts required by law, and Employer's Liability with not less than
         the following limits:

                                       8
<PAGE>

                  Each Accident                               $500,000
                  Disease--Policy Limit                       $500,000
                  Disease--Each Employee                      $500,000

                  Such insurance shall contain a waiver of subrogation provision
         in favor of Landlord and its agents.

Tenant's insurance shall be primary and not contributory to that carried by
Landlord, its agents, or mortgagee. Landlord, and if any, Landlord's building
manager or agent and ground lessor shall be named as additional insureds as
respects to insurance required of Tenant in Section 8C(1). The company or
companies writing any insurance which Tenant is required to maintain under this
Lease, as well as the form of such insurance, shall at all times be subject to
Landlord's approval, and any such company shall be licensed to do business in
the state in which the Building is located. Such insurance companies shall have
an A.M. Best rating of A VI or better.

Tenant shall cause any contractor of Tenant performing work on the Premises to
maintain insurance as follows, with such other terms, coverages and insurers, as
Landlord shall reasonably require from time to time:

                  (1) Commercial General Liability Insurance, including
         contractor's liability coverage, contractual liability coverage,
         completed operations coverage, broad form property damage endorsement,
         and contractor's protective liability coverage, to afford protection
         with limits, for each occurrence, of not less than One Million Dollars
         ($1,000,000) with respect to personal injury, death or property damage.

                  (2) Workers' compensation or similar insurance in form and
         amounts required by law, and Employer's Liability with not less than
         the following limits:

                     Each Accident                               $500,000
                     Disease--Policy Limit                       $500,000
                     Disease--Each Employee                      $500,000

                  Such insurance shall contain a waiver of subrogation provision
         in favor of Landlord and its agents.

         Tenant's contractor's insurance shall be primary and not contributory
to that carried by Tenant, Landlord, their agents or mortgagees. Tenant and
Landlord, and if any, Landlord's building manager or agent, mortgagee or ground
lessor shall be named as additional insured on Tenant's contractor's insurance
policies.

         D. Insurance Certificates. Tenant shall deliver to Landlord
certificates evidencing all required insurance no later than five (5) days prior
to the Commencement Date and each renewal

                                       9
<PAGE>

date. Each certificate will provide for thirty (30) days prior written notice of
cancellation to Landlord and Tenant.

         E. Landlord's Insurance. Landlord shall maintain "All-Risk" property
insurance at replacement cost, including loss of rents, on the Building, and
Commercial General Liability insurance policies covering the common areas of the
Building, each with such terms, coverages and conditions as are normally carried
by reasonably prudent owners of properties similar to the Project. With respect
to property insurance, Landlord and Tenant mutually waive all rights of
subrogation, and the respective "All-Risk" coverage property insurance policies
carried by Landlord and Tenant shall contain enforceable waiver of subrogation
endorsements.

         9. FIRE AND OTHER CASUALTY.

         A. Termination. If a fire or other casualty causes substantial damage
to the Building or the Premises, Landlord shall engage a registered architect to
certify within one (1) month of the casualty to both Landlord and Tenant the
amount of time needed to restore the Building and the Premises to tenantability,
using standard working methods. If the time needed exceeds nine (9) months from
the beginning of the restoration, or two (2) months therefrom if the restoration
would begin during the last twelve (12) months of the Lease, then in the case of
the Premises, either Landlord or Tenant may terminate this Lease, and in the
case of the Building, Landlord may terminate this Lease, by notice to the other
party within ten (10) days after the notifying party's receipt of the
architect's certificate. The termination shall be effective thirty (30) days
from the date of the notice and Rent shall be paid by Tenant to that date, with
an abatement for any portion of the Premises which has been untenantable after
the casualty.

         B. Restoration. If a casualty causes damage to the Building or the
Premises but this Lease is not terminated for any reason, then subject to the
rights of any mortgagees or ground lessors, Landlord shall obtain the applicable
insurance proceeds and diligently restore the Building and the Premises subject
to current Governmental Requirements. Tenant shall replace its damaged
improvements, personal property and fixtures. Rent shall be abated on a per diem
basis during the restoration for any portion of the Premises which is
untenantable, except to the extent that Tenant's negligence caused the casualty.

         10. EMINENT DOMAIN. If a part of the Project is taken by eminent domain
or deed in lieu thereof which is so substantial that the Premises cannot
reasonably be used by Tenant for the operation of its business, then either
party may terminate this Lease effective as of the date of the taking. If any
substantial portion of the Project is taken without affecting the Premises, then
Landlord may terminate this Lease as of the date of such taking. Rent shall
abate from the date of the taking in proportion to any part of the Premises
taken. The entire award for a taking of any kind shall be paid to Landlord, and
Tenant shall have no right to share in the award. All obligations accrued to the
date of the taking shall be performed by the party liable to perform said
obligations, as set forth herein.

                                       10
<PAGE>

         11. RIGHTS RESERVED TO LANDLORD.

         Landlord may exercise at any time any of the following rights
respecting the operation of the Project without liability to Tenant of any kind:

         A. Name. To change the name or street address of the Building or the
suite number(s) of the Premises.

         B. Signs. To install and maintain any signs on the exterior and in the
interior of the Building, and to approve at its sole discretion, prior to
installation, any of Tenant's signs in the Premises visible from the common
areas or the exterior of the Building.

         C. Window Treatments. To approve, at its discretion, prior to
installation, any shades, blinds, ventilators or window treatments of any kind,
as well as any lighting within the Premises that may be visible from the
exterior of the Building or any interior common area.

         D. Keys. To retain and use at any time passkeys to enter the Premises
or any door within the Premises. Tenant shall not alter or add any lock or bolt.

         E. Access. To have access to inspect the Premises upon reasonable prior
notice to Tenant (except in the case of emergency, in which case no notice shall
be required), and to perform its obligations, or make repairs, alterations,
additions or improvements, as permitted by this Lease.

         F. Preparation for Reoccupancy. To decorate, remodel, repair, alter or
otherwise prepare the Premises for reoccupancy at any time after Tenant abandons
the Premises, without relieving Tenant of any obligation to pay Rent.

         G. Heavy Articles. To approve the weight, size, placement and time and
manner of movement within the Building of any safe, central filing system or
other heavy article of Tenant's property. Tenant shall move its property
entirely at its own risk.

         H. Show Premises. To show the Premises to prospective purchasers,
tenants, brokers, lenders, investors, rating agencies or others at any
reasonable time, provided that Landlord gives prior notice to Tenant and does
not materially interfere with Tenant's use of the Premises.

         I. Relocation of Tenant. To relocate Tenant, upon thirty days' prior
written notice, from all or part of the Premises (the "Old Premises") to another
area in the Project (the "new premises"), provided that:

         (1)      the size of the new premises is at least equal to the size of
                  the Old Premises;

         (2)      Landlord pays the cost of moving Tenant and improving the new
                  premises to the standard of the Old Premises. Tenant shall
                  cooperate with Landlord in all reasonable

                                       11
<PAGE>

                  ways to facilitate the move, including supervising the
                  movement of files or fragile equipment, designating new
                  locations for furniture, equipment and new telephone and
                  electrical outlets, and determining the color of paint in the
                  new premises.

         J. Use of Lockbox. To designate a lockbox collection agent for
collections of amounts due Landlord. In that case, the date of payment of Rent
or other sums shall be the date of the agent's receipt of such payment or the
date of actual collection if payment is made in the form of a negotiable
instrument thereafter dishonored upon presentment. However, Landlord may reject
any payment for all purposes as of the date of receipt or actual collection by
mailing to Tenant within 21 days after such receipt or collection a check equal
to the amount sent by Tenant.

         K. Repairs and Alterations. To make repairs or alterations to the
Project and in doing so transport any required material through the Premises, to
close entrances, doors, corridors, elevators and other facilities in the
Project, to open any ceiling in the Premises, or to temporarily suspend services
or use of common areas in the Building. Landlord may perform any such repairs or
alterations during ordinary business hours, except that Tenant may require any
Work in the Premises to be done after business hours if Tenant pays Landlord for
overtime and any other expenses incurred. Landlord may do or permit any work on
any nearby building, land, street, alley or way.

         L. Landlord's Agents. If Tenant is in default under this Lease,
possession of Tenant's funds or negotiation of Tenant's negotiable instrument by
any of Landlord's agents shall not waive any breach by Tenant or any remedies of
Landlord under this Lease.

         M. Building Services. To install, use and maintain through the
Premises, pipes, conduits, wires and ducts serving the Building, provided that
such installation, use and maintenance does not unreasonably interfere with
Tenant's use of the Premises.

         N. Other Actions. To take any other action which Landlord deems
reasonable in connection with the operation, maintenance or preservation of the
Building.

         12. TENANT'S DEFAULT.

         Any of the following shall constitute a default by Tenant:

         A. Rent Default. Tenant fails to pay any Rent when due;

         B. Assignment/Sublease or Hazardous Substances Default. Tenant defaults
in its obligations under Section 17 Assignment and Sublease or Section 28
Hazardous Substances;

         C. Other Performance Default. Tenant fails to perform any other
obligation to Landlord under this Lease, and, in the case of only the first two
(2) such failures during the Term of this Lease, this failure continues for
fifteen (15) days after written notice from Landlord, except that if Tenant

                                       12
<PAGE>

begins to cure its failure within the fifteen (15) day period but cannot
reasonably complete its cure within such period, then, so long as Tenant
continues to diligently attempt to cure its failure, the fifteen (15) day period
shall be extended to sixty (60) days, or such lesser period as is reasonably
necessary to complete the cure;

         D. Credit Default. One of the following credit defaults occurs:

                  (1) Tenant commences any proceeding under any law relating to
         bankruptcy, insolvency, reorganization or relief of debts, or seeks
         appointment of a receiver, trustee, custodian or other similar official
         for Tenant or for any substantial part of its property, or any such
         proceeding is commenced against Tenant and either remains undismissed
         for a period of thirty days or results in the entry of an order for
         relief against Tenant which is not fully stayed within seven days after
         entry;

                  (2) Tenant becomes insolvent or bankrupt, does not generally
         pay its debts as they become due, or admits in writing its inability to
         pay its debts, or makes a general assignment for the benefit of
         creditors;

                  (3) Any third party obtains a levy or attachment under process
         of law against Tenant's leasehold interest.

         E. Vacation or Abandonment Default. Tenant vacates or abandons the
Premises.

         13. LANDLORD REMEDIES.

         A. Termination of Lease or Possession. If Tenant defaults, Landlord may
elect by notice to Tenant either to terminate this Lease or to terminate
Tenant's possession of the Premises without terminating this Lease. In either
case, Tenant shall immediately vacate the Premises and deliver possession to
Landlord, and Landlord may repossess the Premises and may, at Tenant's sole
cost, remove any of Tenant's signs and any of its other property, without
relinquishing its right to receive Rent or any other right against Tenant.

         B. Lease Termination Damages. If Landlord terminates the Lease, Tenant
shall pay to Landlord all Rent due on or before the date of termination, plus
Landlord's reasonable estimate of the aggregate Rent that would have been
payable from the date of termination through the Termination Date, reduced by
the rental value of the Premises calculated as of the date of termination for
the same period, taking into account anticipated vacancy prior to reletting,
reletting expenses and market concessions, both discounted to present value at
the rate of five percent (5%) per annum. If Landlord shall relet any part of the
Premises for any part of such period before such present value amount shall have
been paid by Tenant or finally determined by a court, then the amount of Rent
payable pursuant to such reletting (taking into account vacancy prior to
reletting and any reletting expenses or concessions) shall be deemed to be the
reasonable rental value for that portion of the Premises relet during the period
of the reletting.

                                       13
<PAGE>

         C. Possession Termination Damages. If Landlord terminates Tenant's
right to possession without terminating the Lease and Landlord takes possession
of the Premises itself, Landlord may relet any part of the Premises for such
Rent, for such time, and upon such terms as Landlord in its sole discretion
shall determine, without any obligation to do so prior to renting other vacant
areas in the Building. Any proceeds from reletting the Premises shall first be
applied to the expenses of reletting, including redecoration, repair,
alteration, advertising, brokerage, legal, and other reasonably necessary
expenses. If the reletting proceeds after payment of expenses are insufficient
to pay the full amount of Rent under this Lease, Tenant shall pay such
deficiency to Landlord monthly upon demand as it becomes due. Any excess
proceeds shall be retained by Landlord.

         D. Landlord's Remedies Cumulative. All of Landlord's remedies under
this Lease shall be in addition to all other remedies Landlord may have at law
or in equity. Waiver by Landlord of any breach of any obligation by Tenant shall
be effective only if it is in writing, and shall not be deemed a waiver of any
other breach, or any subsequent breach of the same obligation. Landlord's
acceptance of payment by Tenant shall not constitute a waiver of any breach by
Tenant, and if the acceptance occurs after Landlord's notice to Tenant, or
termination of the Lease or of Tenant's right to possession, the acceptance
shall not affect such notice or termination. Acceptance of payment by Landlord
after commencement of a legal proceeding or final judgment shall not affect such
proceeding or judgment. Landlord may advance such monies and take such other
actions for Tenant's account as reasonably may be required to cure or mitigate
any default by Tenant. Tenant shall immediately reimburse Landlord for any such
advance, and such sums shall bear interest at the default interest rate until
paid.

         E. WAIVER OF TRIAL BY JURY. EACH PARTY WAIVES TRIAL BY JURY IN THE
EVENT OF ANY LEGAL PROCEEDING BROUGHT BY THE OTHER IN CONNECTION WITH THIS
LEASE. EACH PARTY SHALL BRING ANY ACTION AGAINST THE OTHER IN CONNECTION WITH
THIS LEASE IN A FEDERAL OR STATE COURT LOCATED IN ILLINOIS, CONSENTS TO THE
JURISDICTION OF SUCH COURTS, AND WAIVES ANY RIGHT TO HAVE ANY PROCEEDING
TRANSFERRED FROM SUCH COURTS ON THE GROUND OF IMPROPER VENUE OR INCONVENIENT
FORUM.

         F. Litigation Costs. Tenant shall pay Landlord's reasonable attorneys'
fees and other costs in enforcing this Lease, whether or not suit is filed.

         14. SURRENDER. Upon termination of this Lease or Tenant's right to
possession, Tenant shall return the Premises to Landlord in good order and
condition, ordinary wear and casualty damage excepted. If Landlord requires
Tenant to remove any alterations, then Tenant shall remove the alterations in a
good and workmanlike manner and restore the Premises to its condition prior to
their installation.

         15. HOLDOVER. Tenant shall have no right to holdover possession of the
Premises after the expiration or termination of this Lease without Landlord's
prior written consent, which

                                       14
<PAGE>

consent Landlord may withhold in its sole and absolute discretion. If Tenant
retains possession of any part of the Premises after the Term, Tenant shall
become a month-to-month tenant for the entire Premises upon all of the terms of
this Lease as might be applicable to such month-to-month tenancy, except that
Tenant shall pay Base Rent at double the rate in effect immediately prior to
such holdover, computed on a monthly basis for each full or partial month Tenant
remains in possession. Tenant shall also pay Landlord all of Landlord's direct
and consequential damages resulting from Tenant's holdover. No acceptance of
Rent or other payments by Landlord under these holdover provisions shall operate
as a waiver of Landlord's right to regain possession or any other of Landlord's
remedies.

         16. SUBORDINATION TO GROUND LEASES AND MORTGAGES.

         A. Subordination. This Lease shall be subordinate to any present or
future ground lease or mortgage respecting the Project, and any amendments to
such ground lease or mortgage, at the election of the ground lessor or mortgagee
as the case may be, effected by notice to Tenant in the manner provided in this
Lease. The subordination shall be effective upon such notice, but at the request
of Landlord or ground lessor or mortgagee, Tenant shall within ten (10) days of
the request, execute and deliver to the requesting party any reasonable
documents provided to evidence the subordination. Any mortgagee has the right,
at its option, to subordinate its mortgage to the terms of this Lease, without
notice to, nor the consent of, Tenant.

         B. Termination of Ground Lease or Foreclosure of Mortgage. If any
ground lease is terminated or mortgage foreclosed or deed in lieu of foreclosure
given and the ground lessor, mortgagee, or purchaser at a foreclosure sale shall
thereby become the owner of the Project, Tenant shall attorn to such ground
lessor or mortgagee or purchaser without any deduction or setoff by Tenant, and
this Lease shall continue in effect as a direct lease between Tenant and such
ground lessor, mortgagee or purchaser. The ground lessor or mortgagee or
purchaser shall be liable as Landlord only during the time such ground lessor or
mortgagee or purchaser is the owner of the Project. At the request of Landlord,
ground lessor or mortgagee, Tenant shall execute and deliver within ten (10)
days of the request any document furnished by the requesting party to evidence
Tenant's agreement to attorn.

         C. Security Deposit. Any ground lessor or mortgagee shall be
responsible for the return of any security deposit by Tenant only to the extent
the security deposit is received by such ground lessor or mortgagee.

         D. Notice and Right to Cure. The Project is subject to any ground lease
and mortgage identified with name and address of ground lessor or mortgagee in
Appendix D to this Lease (as the same may be amended from time to time by
written notice to Tenant). Tenant agrees to send by registered or certified mail
to any ground lessor or mortgagee identified either in such Appendix or in any
later notice from Landlord to Tenant a copy of any notice of default sent by
Tenant to Landlord. If Landlord fails to cure such default within the required
time period under this Lease, but ground lessor or mortgagee begins to cure
within ten (10) days after such period and proceeds

                                       15
<PAGE>

diligently to complete such cure, then ground lessor or mortgagee shall have
such additional time as is necessary to complete such cure, including any time
necessary to obtain possession if possession is necessary to cure, and Tenant
shall not begin to enforce its remedies so long as the cure is being diligently
pursued.

         E. Definitions. As used in this Section 16, "mortgage" shall include
"deed of trust" and/or "trust deed" and "mortgagee" shall include "beneficiary"
and/or "trustee", "mortgagee" shall include the mortgagee of any ground lessee,
and "ground lessor", "mortgagee", and "purchaser at a foreclosure sale" shall
include, in each case, all of its successors and assigns, however remote.

         17. ASSIGNMENT AND SUBLEASE.

         A. In General. Tenant shall not, without the prior consent of Landlord
in each case, (i) make or allow any assignment or transfer, by operation of law
or otherwise, of any part of Tenant's interest in this Lease, (ii) grant or
allow any lien or encumbrance, by operation of law or otherwise, upon any part
of Tenant's interest in this Lease, (iii) sublet any part of the Premises, or
(iv) permit anyone other than Tenant and its employees to occupy any part of the
Premises. Tenant shall remain primarily liable for all of its obligations under
this Lease, notwithstanding any assignment or transfer. No consent granted by
Landlord shall be deemed to be a consent to any subsequent assignment or
transfer, lien or encumbrance, sublease or occupancy. Tenant shall pay all of
Landlord's attorneys' fees and other expenses incurred in connection with any
consent requested by Tenant or in reviewing any proposed assignment or
subletting. Any assignment or transfer, grant of lien or encumbrance, or
sublease or occupancy without Landlord's prior written consent shall be void. If
Tenant shall assign this Lease or sublet the Premises in its entirety any rights
of Tenant to renew this Lease, extend the Term or to lease additional space in
the Project shall be extinguished thereby and will not be transferred to the
assignee or subtenant, all such rights being personal to Tenant named herein.

         B. Landlord's Consent. Landlord will not unreasonably withhold its
consent to any proposed assignment or subletting. It shall be reasonable for
Landlord to withhold its consent to any assignment or sublease if (i) Tenant is
in default under this Lease, (ii) the proposed assignee or sublessee is a tenant
in the Project or an affiliate of such a tenant or a party that Landlord has
identified as a prospective tenant in the Project, (iii) the financial
responsibility, nature of business, and character of the proposed assignee or
subtenant are not all reasonably satisfactory to Landlord, (iv) in the
reasonable judgment of Landlord the purpose for which the assignee or subtenant
intends to use the Premises (or a portion thereof) is not in keeping with
Landlord's standards for the Building or are in violation of the terms of this
Lease or any other leases in the Project, (v) the proposed assignee or subtenant
is a government entity, or (vi) the proposed assignment is for less than the
entire Premises or for less than the remaining Term of the Lease. The foregoing
shall not exclude any other reasonable basis for Landlord to withhold its
consent.

         C. Procedure. Tenant shall notify Landlord of any proposed assignment
or sublease at least thirty (30) days prior to its proposed effective date. The
notice shall include the name and address of the proposed assignee or subtenant,
its corporate affiliates in the case of a corporation and

                                       16
<PAGE>

its partners in a case of a partnership, an execution copy of the proposed
assignment or sublease, and sufficient information to permit Landlord to
determine the financial responsibility and character of the proposed assignee or
subtenant. As a condition to any effective assignment of this Lease, the
assignee shall execute and deliver in form satisfactory to Landlord at least
fifteen (15) days prior to the effective date of the assignment, an assumption
of all of the obligations of Tenant under this Lease. As a condition to any
effective sublease, subtenant shall execute and deliver in form satisfactory to
Landlord at least fifteen (15) days prior to the effective date of the sublease,
an agreement to comply with all of Tenant's obligations under this Lease, and at
Landlord's option, an agreement (except for the economic obligations which
subtenant will undertake directly to Tenant) to attorn to Landlord under the
terms of the sublease in the event this Lease terminates before the sublease
expires.

         D. Change of Management or Ownership. Any transfer of the direct or
indirect power to affect the management or policies of Tenant or direct or
indirect change in 25% or more of the ownership interest in Tenant shall
constitute an assignment of this Lease.

         E. Excess Payments. If Tenant shall assign this Lease or sublet any
part of the Premises for consideration in excess of the pro-rata portion of Rent
applicable to the space subject to the assignment or sublet, then Tenant shall
pay to Landlord as Additional Rent 50% of any such excess immediately upon
receipt.

         F. Recapture. Landlord may, by giving written notice to Tenant within
thirty (30) days after receipt of Tenant's notice of assignment or subletting,
terminate this Lease with respect to the space described in Tenant's notice, as
of the effective date of the proposed assignment or sublease and all obligations
under this Lease as to such space shall expire except as to any obligations that
expressly survive any termination of this Lease.

         18. CONVEYANCE BY LANDLORD. If Landlord shall at any time transfer its
interest in the Project or this Lease, Landlord shall be released of any
obligations occurring after such transfer, except the obligation to return to
Tenant any security deposit not delivered to its transferee, and Tenant shall
look solely to Landlord's successors for performance of such obligations. This
Lease shall not be affected by any such transfer.

         19. ESTOPPEL CERTIFICATE. Each party shall, within ten (10) days of
receiving a request from the other party, execute, acknowledge in recordable
form, and deliver to the other party or its designee a certificate stating,
subject to a specific statement of any applicable exceptions, that the Lease as
amended to date is in full force and effect, that Tenant is paying Rent and
other charges on a current basis, and that to the best of the knowledge of the
certifying party, the other party has committed no uncured defaults and has no
offsets or claims. The certifying party may also be required to state the date
of commencement of payment of Rent, the Commencement Date, the Termination Date,
the Base Rent, the status of any improvements required to be completed by
Landlord, the amount of any security deposit, and such other matters as may be
reasonably requested. Failure to deliver such statement within the time required
shall be conclusive evidence against the

                                       17
<PAGE>

non-certifying party that this Lease, with any amendments identified by the
requesting party, is in full force and effect, that there are no uncured
defaults by the requesting party, that not more than one month's Rent has been
paid in advance, that the non-certifying party has not paid any security
deposit, and that the non-certifying party has no claims or offsets against the
requesting party.

20. SECURITY DEPOSIT. Tenant shall deposit with Landlord on the date of this
Lease, security for the performance of all of its obligations in the amount set
forth on the Schedule. If Tenant defaults under this Lease, Landlord may use any
part of the Security Deposit to make any defaulted payment, to pay for
Landlord's cure of any defaulted obligation, or to compensate Landlord for any
loss or damage resulting from any default. To the extent any portion of the
deposit is used, Tenant shall within five (5) days after demand from Landlord
restore the deposit to its full amount. Landlord may keep the Security Deposit
in its general funds and shall not be required to pay interest to Tenant on the
deposit amount. If Tenant shall perform all of its obligations under this Lease
and return the Premises to Landlord at the end of the Term, Landlord shall
return all of the remaining Security Deposit to Tenant within thirty (30) days
after the end of the Term. The Security Deposit shall not serve as an advance
payment of Rent or a measure of Landlord's damages for any default under this
Lease.

         If Landlord transfers its interest in the Project or this Lease,
Landlord may transfer the Security Deposit to its transferee. Upon such
transfer, Landlord shall have no further obligation to return the Security
Deposit to Tenant, and Tenant's right to the return of the Security Deposit
shall apply solely against Landlord's transferee.

21. FORCE MAJEURE. Neither party shall be in default under this Lease to the
extent such party is unable to perform any of its obligations on account of any
strike or labor problem, energy shortage, governmental pre-emption or
prescription, national emergency, or any other cause of any kind beyond the
reasonable control of such party ("Force Majeure"); provided, however, that
nothing contained herein shall be construed to extend (a) the due date for
payment of any installment or payment of Rent, or (b) the date upon which Tenant
is required to vacate and surrender the Premises.

         22. TENANT'S PERSONAL PROPERTY AND FIXTURES. Intentionally omitted.

         23. NOTICES. All notices, consents, approvals and similar
communications to be given by one party to the other under this Lease, shall be
given in writing, mailed or personally delivered as follows:

                                       18
<PAGE>

         A. Landlord. To Landlord as follows:

            CarrAmerica Realty Corporation
            Parkway North Center
            Three Parkway North
            Deerfield, IL 60015
            Attn: Gerald J. O'Malley

            with a copy to each of:

            CarrAmerica Realty Corporation
            1850 K Street, N.W.
            Suite 500
            Washington, D.C. 20006
            Attn: Lease Administration

            and:

            CarrAmerica Realty Corporation
            1850 K Street, N.W.
            Suite 500
            Washington, D.C. 20006
            Attn: General Counsel

            and:

            Mayer, Brown & Platt
            190 South LaSalle Street
            Chicago, IL 60603
            Attn: Ivan P. Kane, Esq.

or to such other person at such other address as Landlord may designate by
notice to Tenant.

         B. Tenant. To Tenant as follows:

            ------------------------------------

            ------------------------------------

            ------------------------------------

            ------------------------------------

or to such other person at such other address as Tenant may designate by notice
to Landlord.

                                       19
<PAGE>

         Mailed notices shall be sent by United States certified or registered
mail, or by a reputable national overnight courier service, postage prepaid.
Mailed notices shall be deemed to have been given on the earlier of actual
delivery or three (3) business days after posting in the United States mail in
the case of registered or certified mail, and one business day in the case of
overnight courier.

         24. QUIET POSSESSION. So long as Tenant shall perform all of its
obligations under this Lease, Tenant shall enjoy peaceful and quiet possession
of the Premises against any party claiming through Landlord.

         25. REAL ESTATE BROKER. Tenant represents to Landlord that Tenant has
not dealt with any real estate broker with respect to this Lease except for any
broker(s) listed in the Schedule, and no other broker is in any way entitled to
any broker's fee or other payment in connection with this Lease. Tenant shall
indemnify and defend Landlord against any claims by any other broker or third
party for any payment of any kind in connection with this Lease.

         26. MISCELLANEOUS.

         A. Successors and Assigns. Subject to the limits on Tenant's assignment
contained in Section 17, the provisions of this Lease shall be binding upon and
inure to the benefit of all successors and assigns of Landlord and Tenant.

         B. Date Payments Are Due. Except for payments to be made by Tenant
under this Lease which are due upon demand or are due in advance (such as Base
Rent), Tenant shall pay to Landlord any amount for which Landlord renders a
statement of account within ten days of Tenant's receipt of Landlord's
statement.

         C. Meaning of "Landlord", "Re-Entry, "including" and "Affiliate". The
term "Landlord" means only the owner of the Project and the lessor's interest in
this Lease from time to time. The words "re-entry" and "re-enter" are not
restricted to their technical legal meaning. The words "including" and similar
words shall mean "without limitation." The word "affiliate" shall mean a person
or entity controlling, controlled by or under common control with the applicable
entity. "Control" shall mean the power directly or indirectly, by contract or
otherwise, to direct the management and policies of the applicable entity.

         D. Time of the Essence. Time is of the essence of each provision of
this Lease.

         E. No Option. This document shall not be effective for any purpose
until it has been executed and delivered by both parties; execution and delivery
by one party shall not create any option or other right in the other party.

         F. Severability. The unenforceability of any provision of this Lease
shall not affect any other provision.

                                       20
<PAGE>

         G. Governing Law. This Lease shall be governed in all respects by the
laws of the state in which the Project is located, without regard to the
principles of conflicts of laws.

         H. Lease Modification. Tenant agrees to modify this Lease in any way
requested by a mortgagee which does not cause increased expense to Tenant or
otherwise materially adversely affect Tenant's interests under this Lease.

         I. No Oral Modification. No modification of this Lease shall be
effective unless it is a written modification signed by both parties.

         J. Landlord's Right to Cure. If Landlord breaches any of its
obligations under this Lease, Tenant shall notify Landlord in writing and shall
take no action respecting such breach so long as Landlord promptly begins to
cure the breach and diligently pursues such cure to its completion. Landlord may
cure any default by Tenant; any expenses incurred shall become Additional Rent
due from Tenant on demand by Landlord.

         K. Captions. The captions used in this Lease shall have no effect on
the construction of this Lease.

         L. Authority. Landlord and Tenant each represents to the other that it
has full power and authority to execute and perform this Lease.

         M. Landlord's Enforcement of Remedies. Landlord may enforce any of its
remedies under this Lease either in its own name or through an agent.

         N. Entire Agreement. This Lease, together with all Appendices,
constitutes the entire agreement between the parties. No representations or
agreements of any kind have been made by either party which are not contained in
this Lease.

         O. Landlord's Title. Landlord's title shall always be paramount to the
interest of Tenant, and nothing in this Lease shall empower Tenant to do
anything which might in any way impair Landlord's title.

         P. Light and Air Rights. Landlord does not grant in this Lease any
rights to light and air in connection with Project. Landlord reserves to itself,
the Land, the Building below the improved floor of each floor of the Premises,
the Building above the ceiling of each floor of the Premises, the exterior of
the Premises and the areas on the same floor outside the Premises, along with
the areas within the Premises required for the installation and repair of
utility lines and other items required to serve other tenants of the Building.

         Q. Singular and Plural. Wherever appropriate in this Lease, a singular
term shall be construed to mean the plural where necessary, and a plural term
the singular. For example, if at any

                                       21
<PAGE>

time two parties shall constitute Landlord or Tenant, then the relevant term
shall refer to both parties together.

         R. No Recording by Tenant. Tenant shall not record in any public
records any memorandum or any portion of this Lease.

         S. Exclusivity. Landlord does not grant to Tenant in this Lease any
exclusive right except the right to occupy its Premises.

         T. No Construction Against Drafting Party. The rule of construction
that ambiguities are resolved against the drafting party shall not apply to this
Lease.

         U. Survival. All obligations of Landlord and Tenant under this Lease
which accrue or arise during the Term of this Lease shall survive the
termination of this Lease.

         V. Rent Not Based on Income. No rent or other payment in respect of the
Premises shall be based in any way upon net income or profits from the Premises.
Tenant may not enter into or permit any sublease or license or other agreement
in connection with the Premises which provides for a rental or other payment
based on net income or profit.

         W. Building Manager and Service Providers. Landlord may perform any of
its obligations under this Lease through its employees or third parties hired by
Landlord.

         X. Late Charge and Interest on Late Payments. Without limiting the
provisions of Section 12A, if Tenant fails to pay any installment of Rent or
other charge to be paid by Tenant pursuant to this Lease within five (5)
business days after the same becomes due and payable, then Tenant shall pay a
late charge equal to five percent (5%) of the amount of such payment. In
addition, interest shall be paid by Tenant to Landlord on any late payments of
Rent from the date due until paid at the rate provided in Section 2D(2). Such
late charge and interest shall constitute Additional Rent due and payable by
Tenant to Landlord upon the date of payment of the delinquent payment referenced
above.

         Y. Tenant's Financial Statements. Upon request from Landlord, Tenant
shall provide Landlord with current audited annual and quarterly financial
statements (income and balance sheet).

         27. UNRELATED BUSINESS INCOME. If Landlord is advised by its counsel at
any time that any part of the payments by Tenant to Landlord under this Lease
may be characterized as unrelated business income under the United States
Internal Revenue Code and its regulations, then Tenant shall enter into any
amendment proposed by Landlord to avoid such income, so long as the amendment
does not require Tenant to make more payments or accept fewer services from
Landlord, than this Lease provides.

                                       22
<PAGE>

         28. HAZARDOUS SUBSTANCES. Tenant shall not cause or permit any
Hazardous Substances to be brought upon, produced, stored, used, discharged or
disposed of in or near the Project unless Landlord has consented to such storage
or use in its sole discretion. "Hazardous Substances" include those hazardous
substances described in the Comprehensive Environmental Response, Compensation
and Liability Act of 1980, as amended, 42 U.S.C. Section 9601 et seq., the
Resource Conservation and Recovery Act, as amended, 42 U.S.C. Section 6901 et
seq., any other applicable federal, state or local law, and the regulations
adopted under these laws. If any lender or governmental agency shall require
testing for Hazardous Substances in the Premises, Tenant shall pay for such
testing.

         29. EXCULPATION. Landlord shall have no personal liability under this
Lease; its liability shall be limited to its interest in the Project, and shall
not extend to any other property or assets of Landlord. In no event shall any
officer, director, employee, agent, shareholder, partner, member or beneficiary
of Landlord be personally liable for any of Landlord's obligations hereunder.

         30. RELOCATION OPTION; TERMINATION OPTION. Subject to Subsections B and
C below, Tenant may at its option relocate from the Premises to a vacant space
(such space to be determined by Landlord in its sole discretion) in any Building
located within Parkway North Center and owned by Landlord or an affiliate of
Landlord, which space contains at least 10,000 rentable square feet (the
approximate square footage required to be identified by Tenant in its notice to
Landlord as set forth below) (the "Relocation Space"), upon the same terms
contained in this Lease, excluding the provisions of Appendix C of the Lease and
except for the amount of Base Rent payable during the Relocation Term and the
length of the Term. The term length of the lease with respect to the Relocation
Space shall be five (5) years (the "Relocation Term"). Tenant shall have no
additional relocation option. Upon the commencement of the Relocation Term, this
Lease shall terminate and the parties shall enter into a new lease upon the
terms set forth herein, provided that the obligations of each party accruing
under this Lease prior to the commencement of the Relocation Term shall survive
such termination. Vacant space shall not be eligible to be the Relocation Space
if it is subject to any expansion or renewal options of any current tenant in
the building in which such space is located.

         A. The Base Rent during the Relocation Term shall be the then
prevailing market rate for a comparable term commencing on the first day of the
Relocation Term for tenants of comparable size and creditworthiness for
comparable space in the Building and other first class office buildings in the
vicinity of the Building as reasonably determined by Landlord.

         B. To exercise its option, Tenant must deliver a binding notice (the
"Relocation Notice") to Landlord not less than three (3) months prior to the
last day of the first Lease Year, which notice shall set forth the approximate
amount of square footage required by Tenant in the Relocation Space (but in no
event less than 10,000 rentable square feet). If Tenant fails to give either its
binding notice timely, Tenant will be deemed to have waived its option to
relocate. Following receipt of the Relocation Notice, Landlord shall attempt to
identify a particular Relocation Space containing approximately the amount of
square footage required by Tenant (+/- 20%) and, if Landlord

                                       23
<PAGE>

determines in its sole discretion that a Relocation Space is available, shall
calculate and inform Tenant of the Base Rent for the Relocation Space. Such
calculation shall be final and shall not be recalculated at the actual
commencement of the Relocation Term, if any. On or before the last day of the
first Lease Year, Landlord shall either identify the Relocation Space and inform
Tenant of the Base Rent for the Relocation Space, or shall notify Tenant that it
is unable, in its sole and absolute discretion, to identify a Relocation Space.
Tenant's option to relocate is also subject to the condition that Landlord,
using commercially reasonable efforts, is able in its sole discretion to
identify a Relocation Space. Landlord shall not be liable for any costs,
expenses, claims, or damages arising from its inability to identify a Relocation
Space, and Landlord makes no representations or warranties to Tenant regarding
the Relocation Space.

         C. Tenant's option to relocate is subject to the conditions that: (i)
on the date that Tenant delivers the Relocation Notice to Landlord, Tenant is
not in default under this Lease, and (ii) Tenant shall not have assigned this
Lease, or sublet any portion of the Premises under a sublease which is in effect
at any time during the final 12 months prior to the Relocation Term.

         D. In the event Landlord notifies Tenant that is unable to identify
such Relocation Space, then Tenant may at its option terminate this Lease in its
entirety (the "Termination Option") effective as of the first day of the fourth
(4th) month of the second (2nd) Lease Year (the "Early Termination Date") by
delivering written notice of its intent to terminate this Lease (the
"Termination Notice") to Landlord within fifteen days after the last day of the
first (1st) Lease Year, and simultaneously paying to Landlord the Termination
Fee. If Tenant fails to deliver its Termination Notice timely, Tenant will be
deemed to have waived such Termination Option. If there are any defaults by
Tenant under this Lease as of the date Tenant delivers the Termination Notice or
as of the Early Termination Date, the Termination Option shall be void, and the
Lease shall remain in effect. If Tenant properly exercises its Termination
Option, this Lease shall terminate as of the Early Termination Date. The
"Termination Fee" shall be the sum of the total aggregate amount of the
brokerage commissions, the costs of the Initial Improvements, any rental
abatement, and any other concession granted to Tenant under the terms of this
Lease, which would be unamortized as of the Early Termination Date, assuming
that such total aggregate amount were to be fully amortized over the initial
term of the Lease using an interest rate of ten percent (10%) per annum.

                                       24
<PAGE>

         IN WITNESS WHEREOF, the parties hereto have executed this Lease.

                             LANDLORD:

                             CARRAMERICA REALTY CORPORATION,
                             a Maryland corporation, t/a Parkway North III

                             By: /s/ Gerald J. O'Malley
                             -------------------------------------------------
                             Print Name:  Gerald O'Malley
                             -------------------------------------------------
                             Print Title: Managing Director
                             -------------------------------------------------

                             TENANT:

                             CYTOMEDIX, INC., a Delaware corporation

                             By: /s/ James Cour
                             -------------------------------------------------
                             Print Name:  James Cour
                             -------------------------------------------------
                             Print Title: President
                             -------------------------------------------------

                                       25
<PAGE>

                                   APPENDIX A

                              PLAN OF THE PREMISES

                                  CARRAMERICA

                              THREE PARKWAY NORTH

                                  SECOND FLOOR

                                [GRAPHIC OMITTED]

12/06/99           THREE PARKWAY NORTH        DEERFIELD, ILLINOIS
--------------------------------------------------------------------------------

                                   APPENDIX A
                                  Page 1 of 1
<PAGE>

                                   APPENDIX B

                              RULES AND REGULATIONS

         1. Tenant shall not place anything, or allow anything to be placed near
the glass of any window, door, partition or wall which may, in Landlord's
judgment, appear unsightly from outside of the Premises.

         2. The Project directory shall be available to Tenant solely to display
names and their location in the Project, which display shall be as directed by
Landlord.

         3. The sidewalks, halls, passages, exits, entrances, elevators and
stairways shall not be obstructed by Tenant or used by Tenant for any purposes
other than for ingress to and egress from the Premises. Tenant shall lend its
full cooperation to keep such areas free from all obstruction and in a clean and
sightly condition and shall move all supplies, furniture and equipment as soon
as received directly to the Premises and move all such items and waste being
taken from the Premises (other than waste customarily removed by employees of
the Building) directly to the shipping platform at or about the time arranged
for removal therefrom. The halls, passages, exits, entrances, elevators,
stairways, balconies and roof are not for the use of the general public and
Landlord shall, in all cases, retain the right to control and prevent access
thereto by all persons whose presence in the judgment of Landlord, reasonably
exercised, shall be prejudicial to the safety, character, reputation and
interests of the Project. Neither Tenant nor any employee or invitee of Tenant
shall go upon the roof of the Project.

         4. The toilet rooms, urinals, wash bowls and other apparatuses shall
not be used for any purposes other than that for which they were constructed,
and no foreign substance of any kind whatsoever shall be thrown therein, and to
the extent caused by Tenant or its employees or invitees, the expense of any
breakage, stoppage or damage resulting from the violation of this rule shall be
borne by Tenant.

         5. Tenant shall not cause any unnecessary janitorial labor or services
by reason of Tenant's carelessness or indifference in the preservation of good
order and cleanliness.

         6. Tenant shall not install or operate any refrigerating, heating or
air conditioning apparatus, or carry on any mechanical business without the
prior written consent of Landlord; use the Premises for housing, lodging or
sleeping purposes; or permit preparation or warming of food in the Premises
(warming of coffee and individual meals with employees and guests excepted).
Tenant shall not occupy or use the Premises or permit the Premises to be
occupied or used for any purpose, act or thing which is in violation of any
Governmental Requirement or which may be dangerous to persons or property.

                                   APPENDIX B
                                  Page 1 of 5

<PAGE>

         7. Tenant shall not bring upon, use or keep in the Premises or the
Project any kerosene, gasoline or inflammable or combustible fluid or material,
or any other articles deemed hazardous to persons or property, or use any method
of heating or air conditioning other than that supplied by Landlord.

         8. Landlord shall have sole power to direct electricians as to where
and how telephone and other wires are to be introduced. No boring or cutting for
wires is to be allowed without the consent of Landlord. The location of
telephones, call boxes and other office equipment affixed to the Premises shall
be subject to the approval of Landlord.

         9. No additional locks shall be placed upon any doors, windows or
transoms in or to the Premises. Tenant shall not change existing locks or the
mechanism thereof. Upon termination of the lease, Tenant shall deliver to
Landlord all keys and passes for offices, rooms, parking lot and toilet rooms
which shall have been furnished Tenant.

         In the event of the loss of keys so furnished, Tenant shall pay
Landlord therefor. Tenant shall not make, or cause to be made, any such keys and
shall order all such keys solely from Landlord and shall pay Landlord for any
keys in addition to the two sets of keys originally furnished by Landlord for
each lock.

         10. Tenant shall not install linoleum, tile, carpet or other floor
covering so that the same shall be affixed to the floor of the Premises in any
manner except as approved by Landlord.

         11. No furniture, packages, supplies, equipment or merchandise will be
received in the Project or carried up or down in the freight elevator, except
between such hours and in such freight elevator as shall be designated by
Landlord. Tenant shall not take or permit to be taken in or out of other
entrances of the Building, or take or permit on other elevators, any item
normally taken in or out through the trucking concourse or service doors or in
or on freight elevators.

         12. Tenant shall cause all doors to the Premises to be closed and
securely locked and shall turn off all utilities, lights and machines before
leaving the Project at the end of the day.

         13. Without the prior written consent of Landlord, Tenant shall not use
the name of the Project or any picture of the Project in connection with, or in
promoting or advertising the business of, Tenant, except Tenant may use the
address of the Project as the address of its business.

         14. Tenant shall cooperate fully with Landlord to assure the most
effective operation of the Premises' or the Project's heating and air
conditioning, and shall refrain from attempting to adjust any controls, other
than room thermostats installed for Tenant's use. Tenant shall keep corridor
doors closed.
                                   APPENDIX B
                                  Page 2 of 5
<PAGE>

         15. Tenant assumes full responsibility for protecting the Premises from
theft, robbery and pilferage, which may arise from a cause other than Landlord's
negligence, which includes keeping doors locked and other means of entry to the
Premises closed and secured.

         16. Peddlers, solicitors and beggars shall be reported to the office of
the Project or as Landlord otherwise requests.

         17. Tenant shall not advertise the business, profession or activities
of Tenant conducted in the Project in any manner which violates the letter or
spirit of any code of ethics adopted by any recognized association or
organization pertaining to such business, profession or activities.

         18. No bicycle or other vehicle and no animals or pets shall be allowed
in the Premises, halls, freight docks, or any other parts of the Building except
that blind persons may be accompanied by "seeing eye" dogs. Tenant shall not
make or permit any noise, vibration or odor to emanate from the Premises, or do
anything therein tending to create, or maintain, a nuisance, or do any act
tending to injure the reputation of the Building.

         19. Tenant acknowledges that Building security problems may occur which
may require the employment of extreme security measures in the day-to-day
operation of the Project.

         Accordingly:

                  (a) Landlord may, at any time, or from time to time, or for
regularly scheduled time periods, as deemed advisable by Landlord and/or its
agents, in their sole discretion, require that persons entering or leaving the
Project or the Property identify themselves to watchmen or other employees
designated by Landlord, by registration, identification or otherwise.

                  (b) Tenant agrees that it and its employees will cooperate
fully with Project employees in the implementation of any and all security
procedures.

                  (c) Such security measures shall be the sole responsibility of
Landlord, and Tenant shall have no liability for any action taken by Landlord in
connection therewith, it being understood that Landlord is not required to
provide any security procedures and shall have no liability for such security
procedures or the lack thereof.

         20. Tenant shall not do or permit the manufacture, sale, purchase, use
or gift of any fermented, intoxicating or alcoholic beverages without obtaining
written consent of Landlord.

         21. Tenant shall not disturb the quiet enjoyment of any other tenant.

                                   APPENDIX B
                                  Page 3 of 5

<PAGE>

         22. Tenant shall not provide any janitorial services or cleaning
without Landlord's written consent and then only subject to supervision of
Landlord and at Tenant's sole responsibility and by janitor or cleaning
contractor or employees at all times satisfactory to Landlord.

         23. Landlord may retain a pass key to the Premises and be allowed
admittance thereto at all times to enable its representatives to examine the
Premises from time to time and to exhibit the same and Landlord may place and
keep on the windows and doors of the Premises at any time signs advertising the
Premises for Rent.

         24. No equipment, mechanical ventilators, awnings, special shades or
other forms of window covering shall be permitted either inside or outside the
windows of the Premises without the prior written consent of Landlord, and then
only at the expense and risk of Tenant, and they shall be of such shape, color,
material, quality, design and make as may be approved by Landlord.

         25. Tenant shall not during the term of this Lease canvas or solicit
other tenants of the Building for any purpose.

         26. Tenant shall not install or operate any phonograph, musical or
sound- producing instrument or device, radio receiver or transmitter, TV
receiver or transmitter, or similar device in the Building, nor install or
operate any antenna, aerial, wires or other equipment inside or outside the
Building, nor operate any electrical device from which may emanate electrical
waves which may interfere with or impair radio or television broadcasting or
reception from or in the Building or elsewhere, without in each instance the
prior written approval of Landlord. The use thereof, if permitted, shall be
subject to control by Landlord to the end that others shall not be disturbed.

         27. Tenant shall promptly remove all rubbish and waste from the
Premises.

         28. Tenant shall not exhibit, sell or offer for sale, Rent or exchange
in the Premises or at the Project any article, thing or service, except those
ordinarily embraced within the use of the Premises specified in Section 6 of
this Lease, without the prior written consent of Landlord.

         29. Tenant shall list all furniture, equipment and similar articles
Tenant desires to remove from the Premises or the Building and deliver a copy of
such list to Landlord and procure a removal permit from the Office of the
Building authorizing Building employees to permit such articles to be removed.

         30. Tenant shall not overload any floors in the Premises or any public
corridors or elevators in the Building.

         31. Tenant shall not do any painting in the Premises, or mark, paint,
cut or drill into, drive nails or screws into, or in any way deface any part of
the Premises or the Building, outside or inside, without the prior written
consent of Landlord.

                                   APPENDIX B
                                   Page 4 of 5

<PAGE>

         32. Whenever Landlord's consent, approval or satisfaction is required
under these Rules, then unless otherwise stated, any such consent, approval or
satisfaction must be obtained in advance, such consent or approval may be
granted or withheld in Landlord's sole discretion, and Landlord's satisfaction
shall be determined in its sole judgment.

         33. Tenant and its employees shall cooperate in all fire drills
conducted by Landlord in the Building.

                                   APPENDIX B
                                  Page 5 of 5

<PAGE>

                                   APPENDIX C

                          TENANT IMPROVEMENT AGREEMENT

         1. INITIAL IMPROVEMENTS. Landlord shall cause to be performed the
improvements (the "Initial Improvements") in the Premises in accordance with
plans and specifications approved by Landlord. The Initial Improvements shall be
performed at Landlord's cost, using Building standard materials.

         The Initial Improvements shall consist of the following improvments to
the Premises:

         (a)      Landlord shall demolish all interior non-load bearing walls
                  currently in the Premises as of the date of this Lease, and
                  shall also remove from such walls any existing electrical
                  wiring;

         (b)      Landlord shall patch the walls and repair the ceiling as
                  reasonably required due to the demolition work described
                  above;

         (c)      Landlord shall install light switches near to the entrance to
                  the Premises;

         (d)      Landlord shall paint the wall surfaces in the Premises;

         (e)      Landlord shall install a sink, upper and lower cabinents, a
                  small dishwasher, and an electrical outlet sufficient to serve
                  a normal-size household refrigerator, all as reasonably
                  designated or selected by Landlord.

         In addition to the Initial Improvements, Tenant shall, at Tenant's sole
cost and expense and using materials previously approved in writing by Landlord,
remove all carpeting existing in the Premises as of the date of this Lease and
install new carpeting of Building standard grade or better.

         2. CHANGE ORDERS. If, prior to the Commencement Date, Tenant shall
require improvements or changes (individually or collectively, "Change Orders")
to the Premises in addition to, revision of, or substitution for the Initial
Improvements, Tenant shall deliver to Landlord for its approval plans and
specifications for such Change Orders. If Landlord does not approve of the plans
for Change Orders, Landlord shall advise Tenant of the revisions required.
Tenant shall revise and redeliver the plans and specifications to Landlord
within five (5) business days of Landlord's advice or Tenant shall be deemed to
have abandoned its request for such Change Orders. Tenant shall pay for all
preparations and revisions of plans and specifications, and the construction of
all Change Orders.

                                   APPENDIX C
                                  Page 1 of 3

<PAGE>

         3. COMMENCEMENT DATE DELAY. Commencement Date shall be delayed until
the Initial Improvements have been substantially completed (the "Completion
Date"), except to the extent that the delay shall be caused by any one or more
of the following (a "Tenant Delay"):

                  (a) Tenant's request for Change Orders whether or not any such
Change Orders are actually performed; or

                  (b) Contractor's performance of any Change Orders; or

                  (c) Tenant's request for materials, finishes or installations
requiring unusually long lead times; or

                  (d) Tenant's delay in reviewing, revising or approving plans
and specifications beyond the periods set forth herein; or

                  (e) Tenant's delay in providing information critical to the
normal progression of the project. Tenant shall provide such information as soon
as reasonably possible, but in no event longer than one week after receipt of
such request for information from Landlord; or

                  (f) Tenant's delay in making payments to Landlord for costs of
the Initial Improvements and/or Change Orders in excess of the Landlord's
Contribution; or

                  (g) Any other act or omission by Tenant, its agents,
contractors or persons employed by any of such persons.

If the Commencement Date is delayed for any reason, then Landlord shall cause
Landlord's Architect to certify the date on which the Initial Improvements would
have been completed but for such Tenant Delay, or were in fact completed without
any Tenant Delay.

         4. ACCESS BY TENANT PRIOR TO COMMENCEMENT OF TERM. Landlord at its
discretion may permit Tenant and its agents to enter the Premises prior to the
Commencement Date to prepare the Premises for Tenant's use and occupancy. Any
such permission shall constitute a license only, conditioned upon Tenant's:

                  (a) working in harmony with Landlord and Landlord's agents,
contractors, workmen, mechanics and suppliers and with other tenants and
occupants of the Building;

                  (b) obtaining in advance Landlord's approval of the
contractors proposed to be used by Tenant and depositing with Landlord in
advance of any work (i) security satisfactory to Landlord for the completion
thereof, and (ii) the contractor's affidavit for the proposed work and the
waivers of lien from the contractor and all subcontractors and suppliers of
material; and

                                   APPENDIX C
                                  Page 2 of 3

<PAGE>

                  (c) furnishing Landlord with such insurance as Landlord may
require against liabilities which may arise out of such entry.

         Landlord shall have the right to withdraw such license for any reason
upon twenty-four (24) hours' written notice to Tenant. Landlord shall not be
liable in any way for any injury, loss or damage which may occur to any of
Tenant's property or installations in the Premises prior to the Commencement
Date. Tenant shall protect, defend, indemnify and save harmless Landlord from
all liabilities, costs, damages, fees and expenses arising out of the activities
of Tenant or its agents, contractors, suppliers or workmen in the Premises or
the Building. Any entry and occupation permitted under this Section shall be
governed by Section 5 and all other terms of the Lease.

         5. MISCELLANEOUS.

         Terms used in this Appendix C shall have the meanings assigned to them
in the Lease. The terms of this Appendix C are subject to the terms of the
Lease.

                                   APPENDIX C
                                  Page 3 of 3

<PAGE>

                                   APPENDIX D

                    MORTGAGES CURRENTLY AFFECTING THE PROJECT

Instrument                              Name and Address of Holder
----------                              --------------------------

None                                    N/A

                                   APPENDIX D
                                   Page 1 of 1

<PAGE>

                                   APPENDIX E

                         COMMENCEMENT DATE CONFIRMATION

Landlord:         CarrAmerica Realty Corporation, a Maryland corporation

Tenant:           Cytomedix, Inc., a ________ corporation

This Commencement Date Confirmation is made by Landlord and Tenant pursuant to
that certain Lease dated as of _________, 2000 (the "Lease") for certain
premises known as Suite ____ in the building commonly known as Three Parkway
North (the "Premises"). This Confirmation is made pursuant to Item 8 of the
Schedule to the Lease.

         1. Lease Commencement Date, Termination Date. Landlord and Tenant
hereby agree that the Commencement Date of the Lease is _____________, 2000, and
the Termination Date of the Lease is _______________, 2003.

         2. Acceptance of Premises. Tenant has inspected the Premises and
affirms that the Premises is acceptable in all respects in its current "as is"
condition.

         3. Incorporation. This Confirmation is incorporated into the Lease, and
forms an integral part thereof. This Confirmation shall be construed and
interpreted in accordance with the terms of the Lease for all purposes.

                                  TENANT:

                                  Cytomedix, Inc., a ________ corporation

                                  By:
                                  ---------------------------------------------
                                  Name:
                                  ---------------------------------------------
                                  Title:
                                  ---------------------------------------------

                                  LANDLORD:

                                  CarrAmerica Realty Corporation, a Maryland
                                  corporation, t/a Parkway North III

                                  By:
                                  ---------------------------------------------
                                  Name:
                                  ---------------------------------------------
                                  Title:
                                  ---------------------------------------------

                                   APPENDIX E
                                   Page 1 of 1

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