Document:

Exhibit
10.1

FIRST
AMENDMENT TO

AMENDED AND RESTATED EMPLOYMENT AGREEMENT

This First
Amendment to the Amended and Restated Employment Agreement (this “Amendment”)
is made and entered into as of February 2, 2007 by and between Sciele Pharma,
Inc., a Delaware corporation (the “Company”) and Patrick Fourteau (“Executive”).

WHEREAS, Executive
is employed by the Company pursuant to the terms and conditions of that certain
Amended and Restated Employment Agreement dated January 24, 2006, by and
between First Horizon Pharmaceutical Corporation and Patrick Fourteau (the “Employment
Agreement”); and

WHEREAS, since the
effective date of the Employment Agreement, the Company has changed its name
from “First Horizon Pharmaceutical Corporation” to “Sciele Pharma, Inc.”; and

WHEREAS, the
parties desire to amend Section 5(d) of the Employment Agreement to delete the
provision that the Company will pay Executive’s moving expenses and replace it
with the fact that the Company will reimburse Executive his reasonable
commuting expenses;

NOW THEREFORE, in
consideration of Executive’s continued employment, the covenants set forth
herein and other good and valuable consideration, the receipt and sufficiency
of which are hereby acknowledged, the parties hereto do hereby agree as follows:

1.               Section 5(d) of the
Employment Agreement is hereby amended and restated in its entirety to state
the following:

                        d)            The Company will pay Executive’s
reasonable commuting expenses for his commute between his home 
                and the Company’s
corporate offices, including, without limitation, airfare, transportation
expenses, hotel 
                expenses and meal expenses
while in commute.

2.               Except as expressly amended by this
Amendment, the Employment Agreement shall remain in full force and effect
without modification or amendment.  This
Amendment will form a part of the Employment Agreement for all purposes and the
Employment Agreement and this Amendment will hereafter be read together.

[Signatures provided on following page.]

IN
WITNESS WHEREOF, the parties have executed this Amendment, effective as of the
date first above written.

	
  

  	
  EXECUTIVE:

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
  /s/ Patrick
  Fourteau

  	
   

  
	
   

  	
  Patrick Fourteau

  	
   

  
	
   

  	
  Chief Executive
  Officer and President

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
  COMPANY:

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
  SCIELE PHARMA,
  INC.

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
  /s/ Darrell
  Borne

  	
   

  
	
   

  	
  Darrell Borne

  	
   

  
	
   

  	
  Executive Vice
  President, Chief Financial Officer, Treasurer and SecretaryExhibit 10.1

AMENDMENT TO THE

XBOX 360 PUBLISHER LICENSING AGREEMENT

(Platinum/Classic
Hits Program)

This Amendment to the Xbox 360 Publisher License Agreement (this “Amendment”)
is entered into and effective as of October 1, 2006 (the “Amendment Effective
Date”) by and between Microsoft Licensing, GP,a Nevada general partnership (“Microsoft”), and THQ
Inc. (“Publisher”), and supplements that certain Xbox 360 Publisher License Agreementbetween the parties dated as of  October 31, 2005, as amended (the “Xbox 360
PLA”).

RECITALS

A.            Microsoft and Publisher entered into the Xbox 360 PLA to
establish the terms under which Publisher may publish video games for Microsoft’s
Xbox 360 video game system.

B.            The parties now wish to amend certain terms of the Xbox
360 PLA for Publisher’s continued manufacture and distribution of video games
for the Xbox 360.

Accordingly, for
and in consideration of the mutual covenants and conditions contained herein,
and for other good and valuable consideration, receipt of which each party
hereby acknowledges, Microsoft and Publisher agree as follows:

1.             Definitions; Interpretation

1.1           “Standard
FPU” means an FPU of a Software Title which is not a Hits FPU (defined below in
Section 2.1).

1.2           Except as expressly
provided otherwise in this Amendment, capitalized terms shall have the same
meanings ascribed to them in the Xbox 360 PLA or its amendments.

1.3           The terms of the
Xbox 360 PLA are incorporated by reference, and except and to the extent
expressly modified by this Amendment or any previous amendments, the Xbox 360
PLA shall remain in full force and effect and is hereby ratified and
confirmed.   In the event of any conflict
between this Amendment and the Xbox 360 PLA or any prior amendments thereto,
the terms of this Amendment shall control. 
In the event of any conflict between this Amendment and the Xbox 360
Publisher Guide, the terms of this Amendment shall control.

2.             Hits Programs

2.1           Publisher may elect
to participate in certain Xbox 360 Platinum or Classic Hits or Platinum or Classic
Family Hits programs (collectively referred to herein as “Hits Programs”) for
qualified Software Titles (each unit of such Software Title qualified and
participating in a Hits Program is referred to herein as a “Hit FPU”).  If Publisher elects to participate in a Hits
Program, Publisher must provide Microsoft a) at least **** notice of its intent
to have a certain Software Title participate in the Hits Program; and b) a
completed and signed Hits Programs Election Form in the form attached hereto as
Exhibit 1 no later than **** prior to the targeted Commercial Release of
the Hit FPU.  If a Software Title meets
the applicable participation criteria in a particular Sales Territory at the
time of the targeted Commercial Release date of the Hit FPU and Microsoft
receives the Hits Programs Election Form on time, Publisher is authorized to
manufacture and distribute Hit FPUs in such Sales Territory and at the royalty rate
in Table 2 of Section 3 of this Amendment applicable to “Hit FPUs.”  In
order for a Software Title to qualify as a Hits FPU in a Sales Territory, the
following conditions, as applicable per Hits Program, must be satisfied:

2.1.1        For
all Hits Programs, the Software Title must have been commercially available as
a Standard FPU in the applicable Sales Territory for at least **** but not more
than ****.  Notwithstanding the
foregoing, a Software Title intended to qualify as a Hit FPU in the Japan or
Asian Sales Territories during the period starting on the Amendment Effective
Date until **** may qualify after ****.

* Confidential portion omitted and filed separately
with the Securities and Exchange Commission.

 1
 

2.1.2        To
qualify as a Platinum or Classic Family Hit, the Software Title must (i) have
received an “E,” or, in the event such rating is officially adopted by the
ESRB, an “E10” rating from the ESRB; a “PEGI 3+” or “PEGI 7+” rating in Europe, an “A: All Ages” rating from CERO in Japan
and/or an equivalent rating in the applicable Sales Territory (to the extent
Software Titles are rated by regulatory boards within the applicable Sales
Territory); and (ii) be character based and/or appeal, as determined by
Microsoft in its sole good faith discretion, to children 12 years of age and
younger.  Notwithstanding the foregoing,
annual sports titles will not qualify for the Platinum Family Hits program.

2.1.3        In
any calendar year in a Sales Territory, Publisher may not publish more than
**** Software Titles as part of the Platinum or Classic Hits Family Program.

2.1.4        As
of the date Publisher wishes to Commercially Release the Software Title as a
Hits FPU, Publisher must have manufactured the following minimum quantities of
Standard FPUs of the Software Title for the applicable time period, Sales
Territory and Hits Program.

	
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2.1.5        Software
Titles in the European Sales Region that had an original Commercial Release
date on Xbox 360 before **** may qualify to join the launch of the Classics Program in
Europe if they manufactured in excess of **** as opposed to the ****
listed above.  This is a one time
only choice and the Publisher must confirm its intent to participate by
submitting an Exhibit 1 form no later than ****.

2.2           All Marketing Materials for a Hit FPU must comply with all
Microsoft branding requirements as may be required in each Sales Territory and
Publisher shall submit all such Marketing Materials to Microsoft for its
approval in accordance with the Xbox 360 PLA. 
Notwithstanding the foregoing, all Hit FPUs must comply with the basic
branding and other requirements for Marketing Materials set forth in the Xbox
360 Publisher Guide.

2.3           The Hit FPU version
must be the same or substantially equivalent to the Standard FPU version of the
Software Title.  Publisher may modify or
add additional content or features to the Hit FPU version of the Software Title
(e.g., demos or game play changes) subject to Microsoft’s review and approval,
which approval shall not be unreasonably withheld, and Publisher acknowledges
that any such modifications or additions may require the Software Title to be
re-Certified at Publisher’s expense.

2.4           Publisher
acknowledges that Microsoft may change any of the qualifications for
participation in a Hit Program upon **** advanced written notice to
Publisher.

3.             New Royalty Tables

3.1           The royalty rate
tables in Section 1 of Exhibit A of the Xbox 360 PLA are hereby replaced by the
following:

****

* Confidential portion omitted and filed separately
with the Securities and Exchange Commission.

 2
 

For purposes of
clarification, none of the other royalty provisions of the Xbox 360 PLA are
changed by this Amendment.  The addition
of the “Hits FPU” row in Table 1 above establishes the allowed Wholesale Price
for each Sales Territory (except ****,
which has a Suggested Retail Price) at which the Publisher may sell a Hit
FPU.  If Publishers desires to sell a Hit
FPU for a higher Wholesale or Suggested Retail Price, then that Software Title
will not qualify as a Hit FPU and the Publisher must choose **** royalty rate.  The addition of the “Hits FPU” row in Table 2
above establishes the royalty rate for Hit FPUs manufactured in the three
Manufacturing Regions.

4.             Asia Simship Program

Section 4 of Exhibit 1 to
the Xbox 360 PLA, is hereby deleted in its entirety and replaced by the
following:

The purpose of this program is to encourage Publisher
to release Japanese, North American or European FPUs, that have been
multi-region signed to run on NTSC-J boxes (hereinafter collectively referred
to as “Simship Titles”), in Hong Kong, Singapore and Taiwan (referred to as “Simship
Territory”) at the same time as Publisher releases the Software Title in the
Japan, European and/or North American Sales Territories.  In order for a Software Title to qualify as a
Simship Title, Publisher must release the Software Title in the Simship
Territory on the same date as the Commercial Release date of such Software Title
in the Japan, European and/or North American Sales Territories, wherever the
Software Title was first Commercially Released (referred to as “Original
Territory”).  To the extent that a
Software Title qualifies as a Simship Title, the applicable royalty tier (under
Section 1.b of this Exhibit 1 above) and Unit Discount (under Section
1.d of this Exhibit 1 above) is determined as if all FPUs of such
Software Title manufactured for distribution in both the Original Territory and
the Simship Territory were manufactured for distribution in the Original
Territory.  For example, if a Publisher
initially manufactures **** of a
Software Title for the Japan Sales Territory and simships **** of those units to the Simship
Territory, the royalty fee for all of the FPUs is determined by ****. 
In this example, Publisher would also receive a **** Unit Discount on ****
units for having exceeded the Unit Discount level specified in Section
1. d of this Exhibit 1 above applicable to the Japan Sales
Territory.  Publisher must provide
Microsoft with written notice of its intention to participate in the Asian
Simship Program with respect to a particular Software Title at least **** prior to manufacturing any FPUs
it intends to qualify for the program. 
In its notice, Publisher shall provide all relevant information, including
total number of FPUs to be manufactured, number of FPUs to be simshipped into
the Simship Territory, date of simship, etc. 
Publisher remains responsible for complying with all relevant import,
distribution and packaging requirements as well as any other applicable
requirements set forth in the Xbox 360 Publisher Guide.

5.             North American Sales Territory

Chile is hereby added to
the definition of the North American Sales Territory.

6.             Selling FPUs Across Sales Territories

For the purpose of
clarification, Publisher may not sell FPUs in a certain Sales Territory that
were manufactured and paid for at a different royalty tier than the royalty
tier selected for that Sales Territory. 
For example, if Publisher were to manufacture FPUs for sale in the Asian
Sales Territory, where it has selected and paid **** royalties, Publisher could not sell those FPUs in the
European Sales Territory where it had selected a **** royalty rate.  In other
words, a Publisher may only sell FPUs in a Sales Territory for which it paid
the royalty rate that was selected for that Sales Territory.

* Confidential portion omitted and filed separately
with the Securities and Exchange Commission.

 3
 

IN WITNESS
WHEREOF, the parties hereto have caused this Amendment to be executed as of the
Amendment Effective Date.

	
  MICROSOFT LICENSING, GP

  	
   

  	
  THQ INC.

  
	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  
	
  By (sign)

  	
   

  	
  By (sign)

  
	
   

  	
   

  	
   

  
	
  Name (Print)

  	
   

  	
  Name (Print)

  
	
   

  	
   

  	
   

  
	
  Title

  	
   

  	
  Title

  
	
   

  	
   

  	
   

  
	
  Date (Print
  mm/dd/yy)

  	
   

  	
  Date (Print mm/dd/yy)

  

 

 4
 

EXHIBIT 1

XBOX 360
HITS PROGRAMS ELECTION FORM

PLEASE COMPLETE THE BELOW INFORMATION, SIGN THE
FORM, AND FAX IT TO MICROSOFT AT +1 (425) 708-2300 TO THE ATTENTION OF
MICROSOFT LICENSING, GP (MSLI) AND YOUR ACCOUNT MANAGER.

NOTES:

·                  THIS FORM MUST BE SUBMITTED BY A PUBLISHER AT LEAST ****.

·                 A SEPARATE
FORM MUST BE SUBMITTED FOR EACH SALES TERRITORY IN WHICH THE PUBLISHER WISHES
TO PUBLISH A SOFTWARE TITLE AS PART OF A HITS PROGRAM AND FOR EACH HITS PROGRAM.

	
  1)    Publisher Name:

  	
   

  
	
   

  	
   

  
	
  2)   Xbox 360 Software Title Name:

  	
   

  
	
   

  	
   

  
	
  3)   XMID Number:

  	
   

  
	
   

  	
   

  
	
  4)   Hits Program (circle one)

  	
   

  
	
   

  	
   

  
	
  

  	
  Platinum Hits

  	
   

  	
  Platinum Family Hits

  
	
   

  	
  Classic Hits

  	
   

  	
  Classic Family Hits

  
	
   

  	
   

  
	
  5)   Sales Territory for which
  Publisher wants to publish the Software Title as a Hit FPU (check one):

  
	
   

  	
   

  
	
   

  	
  North American Sales Territory

  	
   

  	
  Japan Sales Territory

  
	
   

  	
  European Sales Territory

  	
   

  	
  Asian Sales Territory

  
	
   

  	
   

  
	
  6)   Date of Commercial Release of
  Software Title in applicable Sales Territory:

  	
   

  
	
   

  	
   

  
	
  7)   Number of Standard FPUs
  manufactured to date for the Software Title in the applicable Sales
  Territory:

  	
   

  
	
   

  	
   

  
	
  8)   Projected Commercial Release
  date of Software Title in the applicable Sales Territory as part of Hits
  Program:

  	
   

  
	
   

  	
   

  
	
  9)   Manufacturing Region for Hit
  FPUs (circle one):        North
  American           European                   Asian

  
														

 

The undersigned
represents that he/she has authority to submit this form on behalf of the above
publisher, and that the information contained herein is true and accurate.

	
   

  	
   

  
	
  

  	
  By (sign)

  
	
   

  	
   

  
	
   

  	
  Name, Title
  (Print)

  
	
   

  	
   

  
	
   

  	
  E-Mail Address
  (for confirmation of receipt)

  
	
   

  	
   

  
	
   

  	
  Date (Print
  mm/dd/yy)

  

 

* Confidential portion omitted and filed separately
with the Securities and Exchange Commission.

 

 5

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