Document:

June 6, 2013

 

Scott Chisholm

2521 Steiner Street

San Francisco, CA 94115

 

Dear Scott:

 

This Transition
and Separation Agreement (the "Agreement") confirms the agreement between Redwood Trust, Inc. (together with its
subsidiaries and affiliates, the “Company”) and you regarding your transition and separation from the Company
as of the earlier of July 1, 2013 or the date upon which your employment is otherwise terminated by you or the Company (the
“Separation Date”). The Company has no liability to you for severance pay or for any other reason. Nonetheless,
contingent upon your provision of the transition services detailed herein, and to assist you in transitioning to other employment,
the Company has agreed to make the payments set forth in this Agreement, to which payments you agree you are not otherwise entitled,
subject to the terms and conditions set forth below.

 

1.Employment
Transition Period; Final Payment of Accrued Wages and Expenses.

 

a)During
the period beginning June 6, 2013 and ending on the Separation Date (the “Transition Period”), you will continue
to be employed in your current position and to receive salary and benefits at the level in effect as of June 6, 2013 (plus, in
the case of each of your June 15, 2013 and June 30, 2013 salary payments, an additional $1,000 of salary). During the Transition
Period, your employment will continue to be terminable on an at-will basis, without cause or notice, by either you or the Company.

 

		i)	In the event that your employment is terminated during the Transition Period by the Company for Cause, as defined in subsection
1a)iii), below, you will receive all wages and accrued, unused vacation or paid time off (“PTO”) owed to you
as of the termination date.

 

		ii)	In the event that your employment is terminated by the Company during the Transition Period other than for Cause, and within
14 days following such termination of employment you execute and allow to become effective the General Release of Claims (the “General
Release”) attached as Exhibit A hereto then you will receive $500,000 payable in a lump sum, on the next regular payroll
date following the effective date of the General Release.

 

		iii)	“Cause” for purposes of this Agreement shall mean and refer to your engaging in an act or omission that
is in bad faith and to the detriment of the Company; misconduct, willful malfeasance, or any act of dishonesty or moral turpitude
by you; your disclosure of Company confidential information not required by your duties; or your engaging in any act of commercial
bribery, any criminal act or perpetration of fraud.

 

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b)On
the Separation Date, you will be paid an amount equal to all accrued wages through the Separation Date, including vacation or PTO
accrued and unused through the Separation Date. You further acknowledge that you will be reimbursed for all preapproved expenses
incurred by you during the Transition Period and submitted by you for payment in accordance with the Company’s expense reimbursement
policies on or before the Separation Date. You agree that the only payments and benefits that you are entitled to receive from
the Company in the future are those specified in this Agreement.

 

2.Separation
Payments and Benefits.

 

a)In
the event you voluntarily resign your employment with the Company effective on the Separation Date, and contingent upon your execution
of the General Release no earlier than the Separation Date and no later than the 14th day following the Separation Date,
you shall be entitled to receive the following payments:

 

		i)	An amount equal to $500,000 payable in a one-time lump sum payment on the first regular payroll date following the effective
date of the General Release; and

 

		ii)	An amount equal to $1,250,000 payable in substantially equal installments on a monthly basis in accordance with the Company’s
normal payroll practices, during the period commencing on January 1, 2014 and ending on December 31, 2015.

 

b)Pursuant
to the terms of the applicable award agreements, in the event you voluntarily resign your employment with the Company effective
on the Separation Date, you will have vested in 76,531 shares of Company common stock pursuant to previously granted Deferred Stock
Units, and all unvested Performance Stock Units and unvested Deferred Stock Units shall be forfeited without payment of any consideration.

 

3.COBRA.
Medical, Dental, and Vision insurance coverage in effect as of the Separation Date will end on the last day of the month in which
the Separate Date falls. You may thereafter elect to continue your health, dental, and vision insurance coverage under COBRA, at
your own expense.

 

4.Return
of Company Property. You will return to the Company all Company documents, files and property in your possession on the
earlier of the Separation Date or the actual date of termination of your employment. Your receipt of the separation payments pursuant
to Section 2 is conditioned upon your compliance with the terms of this Section 4.

 

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5.Maintaining
Confidential Information. You will not disclose any confidential information you acquired while an employee of the Company
to any other person or use such information in any manner that is detrimental to the Company’s interests. By your execution
of this Agreement, you confirm your continuing obligations toward the Company under the Employment and Confidentiality Agreement
executed by you on September 9, 2009 in conjunction with your commencing employment with the Company (the “Confidentiality
Agreement”).

 

6.Cooperation
With the Company. You will cooperate fully with the Company in its defense of or other participation in any administrative,
judicial or other proceeding arising from any charge, complaint or other action which has been or may be filed.

 

7.General
Release of the Company. You understand that by agreeing to this release you are agreeing not to sue, or otherwise file
any claim against, the Company or any of its employees or other agents for any reason whatsoever based on anything that has occurred
as of the date you sign this Agreement.

a)On
behalf of yourself and your heirs and assigns, you hereby release and forever discharge the “Releasees” hereunder,
consisting of the Company, and each of its owners, affiliates, subsidiaries, divisions, parent corporations, predecessors, successors,
assigns, agents, directors, officers, partners, employees, and insurers, and all persons acting by, through, under or in concert
with them, or any of them, of and from any and all manner of action or actions, cause or causes of action, in law or in equity,
suits, debts, liens, contracts, agreements, promises, liability, claims, demands, damages, loss, cost or expense, of any nature
whatsoever, known or unknown, fixed or contingent (hereinafter called “Claims”), which you now have or may hereafter
have against the Releasees, or any of them, by reason of any matter, cause, or thing whatsoever from the beginning of time to the
date hereof, including, without limiting the generality of the foregoing, any Claims arising out of, based upon, or relating to
your hire, employment, remuneration or resignation by the Releasees, or any of them, including any Claims arising under
Title VII of the Civil Rights Act of 1964, as amended by the Civil Rights Act of 1991, 42 U.S.C. § 2000 et seq.;
the Equal Pay Act, 29 U.S.C. § 206(d); the Civil Rights Act of 1866, 42 U.S.C. § 1981; the Family and Medical Leave
Act of 1993, 29 U.S.C. § 2601 et seq.; the Americans with Disabilities Act of 1990, 42 U.S.C. § 12101 et seq.;
the False Claims Act , 31 U.S.C. § 3729 et seq.; the Employee Retirement Income Security Act, 29 U.S.C. § 1001
et seq.; the Worker Adjustment and Retraining Notification Act, 29 U.S.C.  § 2101 et seq. the Fair Labor Standards
Act, 29 U.S.C. § 215 et seq., the Sarbanes-Oxley Act of 2002; the California Labor Code; the employment and civil rights
laws of California; Claims for breach of contract; Claims arising in tort, including, without limitation, Claims of wrongful dismissal
or discharge, discrimination, harassment, retaliation, fraud, misrepresentation, defamation, libel, infliction of emotional distress,
violation of public policy, and/or breach of the implied covenant of good faith and fair dealing; and Claims for damages or other
remedies of any sort, including, without limitation, compensatory damages, punitive damages, injunctive relief and attorney’s
fees.

 

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b)Notwithstanding
the generality of the foregoing, you do not release the following claims:

 

(i)Claims
for unemployment compensation or any state disability insurance benefits pursuant to the terms of applicable state law;

 

(ii)Claims
for workers' compensation insurance benefits under the terms of any worker's compensation insurance policy or fund of the Company;

 

(iii)Claims
to continued participation in certain of the Company's group benefit plans pursuant to the terms and conditions of the federal
law known as COBRA;

(iv)Your
right to bring to the attention of the Equal Employment Opportunity Commission or the California Department of Fair Employment
and Housing claims of discrimination, harassment and retaliation; provided, however, that you do release your right to secure any
damages for such alleged discriminatory treatment;

 

(v)Claims
by you against the Company to enforce the terms of this Agreement, including, without limitation, (A) claims for the payment of
the cash amounts set forth in Sections 1 and 2 of this Agreement in accordance with the terms of this Agreement and (B) claims
for the delivery of the shares of Company common stock underlying the vested Deferred Stock Units described in Section 2 of this
Agreement in accordance with the terms of this Agreement, the applicable award agreements, and applicable law and regulation; and

 

(vi)
Any other obligation of the Company that cannot be waived as a matter of law.

 

c)YOU
ACKNOWLEDGE THAT YOU HAVE BEEN ADVISED OF AND ARE FAMILIAR WITH THE PROVISIONS OF CALIFORNIA CIVIL CODE SECTION 1542, WHICH PROVIDES
AS FOLLOWS:

 

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"A
GENERAL RELEASE DOES NOT EXTEND TO CLAIMS WHICH THE CREDITOR DOES NOT KNOW OR SUSPECT TO EXIST IN HIS OR HER FAVOR AT THE TIME
OF EXECUTING THE RELEASE, WHICH, IF KNOWN BY HIM OR HER, MUST HAVE MATERIALLY AFFECTED HIS OR HER SETTLEMENT WITH THE DEBTOR."

 

BEING
AWARE OF SAID CODE SECTION, YOU HEREBY EXPRESSLY WAIVE ANY RIGHTS YOU MAY HAVE THEREUNDER, AS WELL AS UNDER ANY OTHER STATUTES
OR COMMON LAW PRINCIPLES OF SIMILAR EFFECT.

 

8.Non-disparagement.
You shall not disparage or otherwise communicate to any Company employee, customer, competitor or other person or entity negative
statements about the Company, its employees, products, services, or business. The Company shall instruct its officers and
directors to not disparage or otherwise communicate negative statements about you. If contacted by prospective employers, the Company
will provide, consistent with its standard policy, your job title and dates of employment (and, if you should request us to do
so, we will also provide any such prospective employer with your compensation history while employed by the Company).

 

9.Non-Solicitation.
You acknowledge and agree that the Company has invested substantial time, effort and expense in compiling its confidential and
trade secret information and in assembling its present staff of personnel. In order to protect the confidentiality of the Company’s
Confidential Information (as defined in the Confidentiality Agreement), you agree that, during period from the Separation Date
through December 31, 2015, you shall not do the following:

 

		a)	approach, contact, or otherwise communicate in any way with any customer of the Company with the use or assistance of the Company’s
Confidential Information that you obtained during your employment with the Company for the purpose of engaging in, or assisting
others in, soliciting business from that customer for the sale or distribution of financial products similar to those sold by the
Company or related products or services that would replace those sold by the Company (for the avoidance of doubt, you are not restricted
from approaching, contacting, or otherwise communicating with customers of the Company for the purpose of engaging in, or assisting
others in, soliciting business from those customers for the sale or distribution of financial products similar to those sold by
the Company or related products or services that would replace those sold by the Company provided that you do so without the use
or assistance of the Company’s Confidential Information that you obtained during your employment with the Company unless
that same Confidential Information is independently obtained by you without a breach of your confidentiality obligations to the
Company);

 

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		b)	approach, counsel or attempt to induce any person who is then in the employ of the Company to leave the employ of the Company,
or solicit for employment any person who is in the employ of the Company; or

 

		c)	aid, assist or counsel any other person, firm or corporation to do any of the above.

 

Notwithstanding any provision
of this Agreement or the Confidentiality Agreement, for purposes of both this Agreement and the Confidentiality Agreement the Company’s
Confidential Information shall not include the names and contact information of customers of the Company.

 

10.Injunctive
Relief. You recognize and acknowledge that a breach of the covenants contained in this Agreement will cause irreparable
damage to Company and its goodwill, the exact amount of which will be difficult or impossible to ascertain, and that the remedies
at law for any such breach will be inadequate. Accordingly, you agree that in the event of a breach of any of the covenants contained
in this Agreement, in addition to any other remedy which may be available at law or in equity, the Company will be entitled to
specific performance and injunctive relief.

 

11.Severability.
The provisions of this Agreement are severable. If any provision is held to be invalid or unenforceable, it shall not affect
the validity or enforceability of any other provision.

 

12.Choice
of Law. This Agreement shall in all respects be governed and construed in accordance with the laws of the State of California,
including all matters of construction, validity and performance, without regard to conflicts of law principles.

 

13.Voluntary
and Knowing Agreement. You represent that you have thoroughly read and considered all aspects of this Agreement, that you
understand all its provisions and that you are voluntarily entering into said Agreement.

 

14.Entire
Agreement; Amendment. This Agreement sets forth the entire agreement between you and the Company and supersedes any and
all prior oral or written agreements or understanding between you and the Company concerning the subject matter hereof. This Agreement
may not be altered, amended or modified, except by a further written document signed by both (i) you and (ii) one of the Chief
Executive Officer or the General Counsel of the Company, on behalf of the Company.

 

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If the above
accurately reflects your understanding, please date and sign the enclosed copy of this letter in the places indicated below and
return that copy to Andrew Stone, General Counsel, by email or fax at (415) 381-1773.

 

 

	 	Respectfully,
	 	 
	 	/s/ Martin S. Hughes
	 	 
	 	Martin S. Hughes
	 	Chief Executive Officer,
	 	Redwood Trust, Inc.

 

	Accepted and agreed to on this 6th day of June, 2013.	 
	 	 	 
	 	 	 
	/s/ Scott Chisholm 	 	 
	Scott Chisholm	 	 

 

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EXHIBIT
A

 

GENERAL
RELEASE OF CLAIMS

 

This General
Release of Claims (“Release”) is entered into as of this ___ day of July, 2013, between you, and Redwood Trust, Inc.
(together with its subsidiaries and affiliates, the “Company”) (with you and the Company collectively referred to herein
as the “Parties”), effective eight days after your signature (the “Effective Date”), unless you revoke
your acceptance as provided in Paragraph 1(c), below.

 

		1.	General Release of the Company. You understand that by agreeing to this release you
are agreeing not to sue, or otherwise file any claim against, the Company or any of its employees or other agents for any reason
whatsoever based on anything that has occurred as of the date you sign this agreement.

 

		a)	On behalf of yourself and your heirs and assigns, you hereby release and forever discharge the
“Releasees” hereunder, consisting of the Company, and each of its owners, affiliates, subsidiaries, divisions,
parent corporations, predecessors, successors, assigns, agents, directors, officers, partners, employees, and insurers, and all
persons acting by, through, under or in concert with them, or any of them, of and from any and all manner of action or actions,
cause or causes of action, in law or in equity, suits, debts, liens, contracts, agreements, promises, liability, claims, demands,
damages, loss, cost or expense, of any nature whatsoever, known or unknown, fixed or contingent (hereinafter called “Claims”),
which you now have or may hereafter have against the Releasees, or any of them, by reason of any matter, cause, or thing whatsoever
from the beginning of time to the date hereof, including, without limiting the generality of the foregoing, any Claims arising
out of, based upon, or relating to your hire, employment, remuneration or resignation by the Releasees, or any of them, including
any Claims arising under the Age Discrimination in Employment Act (“ADEA”), as amended, 29 U.S.C. § 621,
et seq.; Title VII of the Civil Rights Act of 1964, as amended by the Civil Rights Act of 1991, 42 U.S.C. § 2000 et seq.;
the Equal Pay Act, 29 U.S.C. § 206(d); the Civil Rights Act of 1866, 42 U.S.C. § 1981; the Family and Medical Leave Act
of 1993, 29 U.S.C. § 2601 et seq.; the Americans with Disabilities Act of 1990, 42 U.S.C. § 12101 et seq.; the False
Claims Act , 31 U.S.C. § 3729 et seq.; the Employee Retirement Income Security Act, 29 U.S.C. § 1001 et seq.; the Worker
Adjustment and Retraining Notification Act, 29 U.S.C. § 2101 et seq. the Fair Labor Standards Act, 29 U.S.C. § 215 et
seq., the Sarbanes-Oxley Act of 2002; the California Labor Code; the employment and civil rights laws of California; Claims for
breach of contract; Claims arising in tort, including, without limitation, Claims of wrongful dismissal or discharge, discrimination,
harassment, retaliation, fraud, misrepresentation, defamation, libel, infliction of emotional distress, violation of public policy,
and/or breach of the implied covenant of good faith and fair dealing; and Claims for damages or other remedies of any sort, including,
without limitation, compensatory damages, punitive damages, injunctive relief and attorney’s fees.

 

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		b)	Notwithstanding the generality of the foregoing, you do not release the following
claims:

 

(i)Claims
for unemployment compensation or any state disability insurance benefits pursuant to the terms of applicable state law;

 

(ii)Claims
for workers' compensation insurance benefits under the terms of any worker's compensation insurance policy or fund of the Company;

 

(iii)Claims
to continued participation in certain of the Company's group benefit plans pursuant to the terms and conditions of the federal
law known as COBRA;

 

(iv)Your
right to bring to the attention of the Equal Employment Opportunity Commission or the California Department of Fair Employment
and Housing claims of discrimination, harassment and retaliation; provided, however, that you do release your right to secure any
damages for such alleged treatment;

 

(v)Claims
by you against the Company to enforce the terms of the Agreement dated as of June 6, 2013, including, without limitation, (A) claims
for the payment of the cash amounts set forth in Sections 1 and 2 of the Agreement dated as of June 6, 2013 in accordance with
the terms of that Agreement and (B) claims for the delivery of the shares of Company common stock underlying the vested Deferred
Stock Units described in Section 2 of the Agreement dated as of June 6, 2013 in accordance with the terms of that Agreement, the
applicable award agreements, and applicable law and regulation; and

 

(vi)Any
other obligation of the Company that cannot be waived as a matter of law.

 

		c)	YOU ACKNOWLEDGE THAT YOU HAVE BEEN ADVISED OF AND ARE
FAMILIAR WITH THE PROVISIONS OF CALIFORNIA CIVIL CODE SECTION 1542, WHICH PROVIDES AS FOLLOWS:

 

"A
GENERAL RELEASE DOES NOT EXTEND TO CLAIMS WHICH THE CREDITOR DOES NOT KNOW OR SUSPECT TO EXIST IN HIS OR HER FAVOR AT THE TIME
OF EXECUTING THE RELEASE, WHICH, IF KNOWN BY HIM OR HER, MUST HAVE MATERIALLY AFFECTED HIS OR HER SETTLEMENT WITH THE DEBTOR."

 

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BEING
AWARE OF SAID CODE SECTION, YOU HEREBY EXPRESSLY WAIVE ANY RIGHTS YOU MAY HAVE THEREUNDER, AS WELL AS UNDER ANY OTHER STATUTES
OR COMMON LAW PRINCIPLES OF SIMILAR EFFECT.

 

		2.	OWBPA Notice. In accordance with the Older Workers Benefit Protection Act of 1990, you acknowledge that you are
aware of the following:

 

		a)	This paragraph, and this Release, are written in a manner
calculated to be understood by you.

		 	 

		b)	The waiver and release of claims under the ADEA contained
in this Release does not cover rights or claims that may arise after the date on which you sign this Release.

		 	 

		c)	Together with the Agreement dated as of June 6, 2013,
this Release provides for consideration in addition to anything of value to which you are already entitled.

		 	 

		d)	You have been advised to consult an attorney before signing
this Release.

		 	 

		e)	You have been granted twenty-one (21) days after you
are presented with this Release to decide whether or not to sign this Release. If you execute this Release prior to the expiration
of such period, you do so voluntarily and after having had the opportunity to consult with an attorney, and hereby waive the remainder
of the twenty-one (21) day period.

		 	 

		f)	You have the right to revoke this Release within seven (7)
days of signing it. In the event this Release is revoked, the June 6, 2013 Agreement will be null and void in its entirety, and
you will not receive the benefits of that Agreement.

 

If
you wish to revoke this agreement, you must deliver written notice stating that intent to revoke to Andy Stone, General Counsel,
by email or fax at (415) 381-1773, on or before 5:00 p.m. on the seventh (7th) day after the date on which you sign
this Release.

 

3.Employee’s
Representations. You represent and warrant that:

 

		a)	You have returned to the Company all Company property in your possession;

 

		b)	You have been paid all wages, commissions, bonuses or other compensation, owed to you;

 

		c)	During the course of your employment you did not sustain any injuries for which you might be entitled
to compensation pursuant to worker’s compensation law;

 

		d)	You have not made any disparaging comments about the Company, nor will you do so in the future;
and

 

		e)	You have not initiated any adversarial proceedings of any kind against the Company or against any
other person or entity released herein, nor will you do so in the future, except as specifically allowed by this Agreement.

 

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5.Severability.
The provisions of this Release are severable. If any provision is held to be invalid or unenforceable, it shall not affect
the validity or enforceability of any other provision.

 

6.Choice of Law.
The Agreement dated June 6, 2013 and this Release shall in all respects be governed and construed in accordance with the laws of
the State of California, including all matters of construction, validity and performance, without regard to conflicts of law principles.

 

7.Integration Clause.
This Release and the Agreement dated June 6, 2013 contain our entire agreement with regard to the transition and separation of
your employment, and supersede and replace any prior agreements as to those matters, whether oral or written. This Release may
not be changed or modified, in whole or in part, except by an instrument in writing signed by both (i) you and (ii) one of the
Chief Executive Officer or the General Counsel of the Company, on behalf of the Company.

 

8.Execution in Counterparts.
This Release may be executed in counterparts with the same force and effectiveness as though executed in a single document. Facsimile
signatures shall have the same force and effectiveness as original signatures.

 

The Parties have carefully read
this Release in its entirety; fully understand and agree to its terms and provisions; and intend and agree that it is final and
binding on all Parties.

 

IN WITNESS WHEREOF, and intending
to be legally bound, the Parties have executed the foregoing on the dates shown below.

 

	SCOTT CHISHOLM	 	REDWOOD TRUST, INC.
	 	 	 	 	 
	 	 	 	 	 
	 	 	 
	 	 	 	By:  	 
	 	 	 	Title:  	 
	 	 	 	 	 
	 	 	 	 	 
	Date	 	 	Date	 

 

    	11AMENDMENT NO. 1 TO THE PURCHASE AGREEMENT

 

This Amendment No.
1 (the “Amendment”) is executed as of June 7, 2013 and is made to that certain Purchase Agreement (the “Purchase
Agreement”), dated as of February 18, 2013, by and between Cytomedix, Inc., a Delaware corporation, (the “Company”),
and Lincoln Park Capital Fund, LLC, an Illinois limited liability company (the “Investor”). The Company and the Investor
are referred to collectively as the Parties and individually as a Party. Terms used as defined terms herein and not otherwise defined
shall have the meanings provided thereto in the Purchase Agreement.

 

RECITALS

 

WHEREAS, on
February 18, 2013, the Company and the Investor entered into the Purchase Agreement; and

 

WHEREAS, Section
12(o) provides, in pertinent part, that no provision of the Purchase Agreement may be amended or waived by the parties from and
after the date that is a business day immediately preceding the initial filing of the Registration Statement with the SEC, and,
subject to the immediately preceding sentence, no provision of this Purchase Agreement may be amended other than by a written instrument
signed by both parties thereto; and

 

WHEREAS, the
parties to the Purchase Agreement wish to amend certain terms of the Purchase Agreement as set forth below, and a Registration
Statement has not been filed with the SEC.

 

NOW THEREFORE,
in consideration of the mutual covenants contained in this Agreement, and for other good and valuable consideration, the receipt
and adequacy of which are hereby acknowledged, the Company and the Investor hereby agree as follows:

 

1.Section 2 of the Purchase Agreement
is hereby amended and modified by adding Section 2(f) set forth below to read in its entirety as follows:

 

(f)Compliance with Rules of
Principal Market.

 

(i)Exchange Cap. Subject
to Section 2(f)(ii) below, the Company shall not issue or sell any shares of Common Stock pursuant to this Agreement, and the
Investor shall not purchase or acquire any shares of Common Stock pursuant to this Agreement, to the extent that after giving
effect thereto, the aggregate number of shares of Common Stock that would be issued pursuant to this Agreement would exceed the
maximum number of shares of Common Stock that the Company may issue pursuant to this Agreement (taking into account all shares
of Common Stock issued or issuable pursuant to any transaction or series of transactions that may be aggregated with the transactions
contemplated by this Agreement under applicable rules of The NASDAQ Stock Market or any other Principal Market on which the Common
Stock may be listed or quoted) without (1) breaching the Company’s obligations under the applicable rules of The NASDAQ
Stock Market or any other Principal Market on which the Common Stock may be listed or quoted or (2) obtaining stockholder approval
under the applicable rules of The NASDAQ Stock Market or any other Principal Market on which the Common Stock may be listed or
quoted (the “Exchange Cap”), unless and until the Company elects to solicit stockholder approval of the transactions
contemplated by this Agreement and the stockholders of the Company have in fact approved the transactions contemplated by this
Agreement in accordance with the applicable rules and regulations of The NASDAQ Stock Market, any other Principal Market on which
the Common Stock may be listed or quoted, and the Restated Certificate of Formation and By-laws of the Company. For the avoidance
of doubt, the Company may, but shall be under no obligation to, request its stockholders to approve the transactions contemplated
by this Agreement; provided, that if stockholder approval is not obtained in accordance with this Section 2(f)(i), the Exchange
Cap shall be applicable for all purposes of this Agreement and the transactions contemplated hereby at all times during the term
of this Agreement (except as set forth in Section 2(f)(ii) below).

    	 

    	 

    

 

(ii)At-Market Transaction.
Notwithstanding Section 2(f)(i) above, the Exchange Cap shall not be applicable for any purposes of this Agreement and the transactions
contemplated hereby, solely to the extent that (and only for so long as) the Average Price shall equal or exceed the Base Price
(it being hereby acknowledged and agreed that the Exchange Cap shall be applicable for all purposes of this Agreement and the transactions
contemplated hereby at all other times during the term of this Agreement, unless the stockholder approval referred to in Section
2(f)(i) is obtained).

 

(iii)General. The Company
shall not issue any shares of Common Stock pursuant to this Agreement if such issuance would reasonably be expected to result in
a breach of the rules and regulations of The NASDAQ Stock Market or any other Principal Market on which the Common Stock may be
listed or quoted. The provisions of this Section 2(f) shall be implemented in a manner otherwise than in strict conformity
with the terms hereof only if necessary to ensure compliance with the rules and regulations of The NASDAQ Stock Market or any other
Principal Market on which the Common Stock may be listed or quoted. As used in this Section 2(f), “Average Price”
means a price per Purchase Share (rounded to the nearest tenth of a cent) equal to the quotient obtained by dividing (i) the aggregate
gross purchase price paid by the Investor for all Purchase Shares purchased pursuant to this Agreement, by (ii) the aggregate number
of Purchase Shares issued pursuant to this Agreement. “Base Price” means a price per Purchase Share equal to
the sum of (i) the Signing Market Price and (ii) $0.0182 (subject to adjustment for any reorganization, recapitalization, non-cash
dividend, stock split, reverse stock split or other similar transaction that occurs on or after the date of this Amendment). “Signing
Market Price” means $0.49, representing the consolidated closing bid price of the Common Stock on The NASDAQ Capital
Market on the Business Day immediately preceding the date of this Amendment.

 

2.Section 4(d) of the Purchase Agreement
is hereby amended, modified and restated in its entirety to read as follows:

 

“(d)Issuance
of Securities. Upon issuance and payment thereof in accordance with the terms and conditions of this Agreement, the Purchase
Shares shall be validly issued, fully paid and nonassessable and free from all taxes, liens, charges, restrictions, rights
of first refusal and preemptive rights with respect to the issue thereof, with the holders being entitled to all rights accorded
to a holder of Common Stock. 10,000,000 shares of Common Stock have been duly authorized and reserved for issuance upon purchase
under this Agreement as Purchase Shares. 375,000 shares of Common Stock (subject to equitable adjustment for any reorganization,
recapitalization, non-cash dividend, stock split or other similar transaction) have been duly authorized and reserved
for issuance as Additional Commitment Shares (as defined below in Section 5(e)) in accordance with this Agreement. When
issued in accordance with this Agreement, the Commitment Shares shall be validly issued, fully paid and non-assessable
and free from all taxes, liens, charges, restrictions, rights of first refusal and preemptive rights with respect to the
issue thereof, with the holders being entitled to all rights accorded to a holder of Common Stock.”

 

3.Section 8(g) of the Purchase Agreement
is hereby amended, modified and restated in its entirety to read as follows:

 

    	 

    	 

    

“(g)As of
the Commencement Date, the Company shall have reserved out of its authorized and unissued Common Stock, (A) solely for
the purpose of effecting purchases of Purchase Shares hereunder, 10,000,000 shares of Common Stock and (B) as Additional Commitment
Shares in accordance with Section 5(e) hereof, 375,000 shares of Common Stock;”

 

4.Section 10 of the Purchase Agreement
is hereby amended and modified by adding Section 10(i) set forth below to read in its entirety as follows:

 

“(i)if
at any time after the Commencement Date, the Exchange Cap is reached (to the extent such Exchange Cap is applicable pursuant to
Section 2(f) hereof).”

 

All
other terms and conditions of the Purchase Agreement shall remain unchanged and in full force and effect and the terms of and
provisions of Section 12 of the Purchase Agreement are hereby incorporated by reference herein.

 

IN WITNESS WHEREOF, the Investor
and the Company have caused this Amendment to be duly executed as of the date first written above.

 

	 	THE COMPANY:
	 	 	 
	 	CYTOMEDIX, INC.
	 	 	 
	 	By: 	/s/ Martin P. Rosendale
	 	Name: 	Martin P. Rosendale
	 	Title:   	Chief Executive Officer
	 	 	 
	 	 	 
	 	INVESTOR:
	 	 	 
	 	LINCOLN PARK CAPITAL FUND, LLC
	 	BY: LINCOLN PARK CAPITAL, LLC
	 	BY: ALEX NOAH INVESTORS, INC. 
	 	 	 
	 	By:	/s/ Jonathan Cope
	 	Name: 	Jonathan Cope
	 	Title: 	President

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00218-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00218-of-00352.parquet"}]]