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                                                                     Exhibit 4.3

                                  HOSPIRA, INC.

                          SUPPLEMENTAL INDENTURE NO. 1

                        $300,000,000 4.95% Notes due 2009
                        $400,000,000 5.90% Notes due 2014

     THIS SUPPLEMENTAL INDENTURE NO. 1, dated as of June 14, 2004 (the
"Supplemental Indenture"), between HOSPIRA, INC., a Delaware corporation (the
"Company"), and LASALLE BANK NATIONAL ASSOCIATION, a national banking
association, as trustee (the "Trustee").

                            RECITALS OF THE COMPANY:

     WHEREAS, the Company has heretofore executed and delivered to the Trustee
an Indenture, dated as of June 14, 2004 (the "Indenture"), providing for the
issuance from time to time of one or more series of Securities (as defined in
the Indenture);

     WHEREAS, Article Nine of the Indenture provides for various matters with
respect to any series of Securities issued under the Indenture to be established
in an indenture supplemental to the Indenture;

     WHEREAS, Section 9.1(7) of the Indenture provides that the Company and the
Trustee may enter into an indenture supplemental to the Indenture to establish
the form or terms of Securities of any series as permitted by Sections 2.1 and
3.1 of the Indenture; and

     WHEREAS, all the conditions and requirements necessary to make this
Supplemental Indenture, when duly executed and delivered, a valid and binding
agreement in accordance with its terms and for the purposes herein expressed,
have been performed and fulfilled.

     NOW THEREFORE, THIS SUPPLEMENTAL INDENTURE WITNESSETH:

     For and in consideration of the premises and the issuance of the series of
Securities provided for herein, the Company and the Trustee mutually covenant
and agree for the equal and proportionate benefit of the respective Holders of
the Securities of each such series as follows:

                                   ARTICLE ONE

            RELATION TO INDENTURE; DEFINITIONS; RULES OF CONSTRUCTION

     SECTION 1.1  RELATION TO INDENTURE. This Supplemental Indenture constitutes
an integral part of the Indenture.

     SECTION 1.2  DEFINITIONS. For all purposes of this Supplemental Indenture,
the following terms shall have the respective meanings set forth in this
Section.

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          "2009 Notes" means the $300,000,000 4.95% Notes due 2009.

          "2014 Notes" means the $400,000,000 5.90% Notes due 2014.

          "Applicable Procedures" means, with respect to any transfer or
     transaction involving a Regulation S Global Note or beneficial interest
     therein, the rules and procedures of the Depositary for such Global Note,
     Euroclear and Clearstream, in each case to the extent applicable to such
     transaction and as in effect from time to time.

          "Clearstream" means Clearstream Banking, societe anonyme, Luxembourg.

          "Definitive Note" means a certificated Initial Note or Exchange Note
     (bearing the Restricted Notes Legend if the transfer of such Note is
     restricted by applicable law) that does not include the Global Notes
     Legend.

          "Depositary" means The Depository Trust Company, its nominees and
     their respective successors.

          "Euroclear" means Euroclear Bank S.A./N.V., as operator of the
     Euroclear System.

          "Exchange Notes" means the Notes of the Company issued in exchange for
     Initial Notes pursuant to the Indenture and this Supplemental Indenture in
     connection with the Registered Exchange Offer.

          "Global Notes Legend" means the legend set forth in Exhibits A1 and A2
     to this Supplemental Indenture.

          "IAI" means an institutional "accredited investor" as described in
     Regulation D.

          "IAI Notes" means all Notes held by an IAI.

          "Initial Purchasers" means Morgan Stanley & Co. Incorporated, ABN AMRO
     Incorporated and Citigroup Global Markets Inc. and the other initial
     purchasers listed on Schedule I to the Purchase Agreement.

          "Initial Notes" means the IAI Notes, the Rule 144A Notes and the
     Regulation S Notes.

          "Notes" means the 2009 Notes and the 2014 Notes.

          "Notes Custodian" means the custodian with respect to a Global Note
     (as appointed by the Depositary) or any successor person thereto, who will
     initially be the Trustee.

          "Participant" means members of, or participants in, the Depositary.

          "Purchase Agreement" means the Purchase Agreement dated June 7, 2004,
     among the Company and the Initial Purchasers.

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          "QIB" means a "qualified institutional buyer" as defined in Rule 144A.

          "Registered Exchange Offer" means the offer by the Company, pursuant
     to the Registration Agreement, to certain Holders of Initial Notes, to
     issue and deliver to such Holders, in exchange for their Initial Notes, a
     like aggregate principal amount of Exchange Notes registered under the
     Securities Act.

          "Registration Agreement" means the Registration Rights Agreement dated
     June 14, 2004, among the Company and the Initial Purchasers.

          "Regulation D" means Rule 501(a)(1), (2), (3) and 7 under the
     Securities Act.

          "Regulation S" means Regulation S under the Securities Act.

          "Regulation S Notes" means all Notes offered and sold outside the
     United States in reliance on Regulation S.

          "Restricted Period" with respect to any Notes means the period of 40
     consecutive days beginning on and including the later of (i) the day on
     which such Notes are first offered to persons other than distributors (as
     defined in Regulation S under the Securities Act) in reliance on Regulation
     S and (ii) the Original Issue Date with respect to such Notes.

          "Restricted Notes Legend" means the legend set forth in Section
     2.4(e)(i) herein.

          "Rule 144A" means Rule 144A under the Securities Act.

          "Rule 144A Notes" means all Notes offered and sold to QIBs in reliance
     on Rule 144A.

          "Securities Act" means the Securities Act of 1933, as amended.

          "Shelf Registration Statement" means a registration statement filed
     by the Company in connection with the offer and sale of the Initial Notes
     pursuant to Section 2(b) of the Registration Agreement.

          "Transfer Restricted Notes" means Definitive Notes and any other
     Notes that bear or are required to bear the Restricted Notes Legend.

     SECTION 1.3  AMENDMENT TO SECTION 5.1 OF THE INDENTURE. For the sole
benefit of the Holders of the Notes, Section 5.1 of the Indenture shall be
amended by adding the following subsection (8) as an Event of Default:

     (8)  the failure to pay when due (subject to any applicable grace period)
     the Principal of, or acceleration of, any indebtedness for money borrowed
     by the Company or by any Domestic Subsidiary having an aggregate principal
     amount of at least $25.0 million, if in the case of any such failure, such
     indebtedness has not been discharged or, in the case of any such
     acceleration, such acceleration has not

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     been rescinded or annulled, in each case within 10 days after written
     notice has been given by the Trustee, or the Holders of at least 25% in
     aggregate principal amount of the outstanding Notes of that series.

     SECTION 1.4  RULES OF CONSTRUCTION.  For all purposes of this Supplemental
Indenture:

          (a)     capitalized terms used herein without definition shall have
     the meanings specified in the Indenture;

          (b)     all references herein to Articles and Sections, unless
     otherwise specified, refer to the corresponding Articles and Sections of
     this Supplemental Indenture;

          (c)     the terms "herein," "hereof," "hereunder" and other words of
     similar import refer to this Supplemental Indenture; and

          (d)     in the event of a conflict with the definition of terms in the
     Indenture, the definitions in this Supplemental Indenture shall control.

                                   ARTICLE TWO

                                 THE SECURITIES

     SECTION 2.1  TITLE OF THE NOTES. There shall be (i) a Series of securities
designated the 4.95% Notes due 2009 and (ii) a Series of securities designated
the 5.90% Notes due 2014.

     SECTION 2.2  LIMITATION ON AGGREGATE PRINCIPAL AMOUNT. The 4.95% Notes due
2009 will be initially issued in an aggregate principal amount of $300,000,000
and the 5.90% Notes due 2014 will be initially issued in an aggregate principal
amount of $400,000,000 .

     SECTION 2.3  FORM AND DATING.

     (a)  GENERAL.  The 2009 Notes and the Trustee's certificate of
authentication shall be substantially in the form of Exhibit A1 hereto. The 2014
Notes and the Trustee's certificate of authentication shall be substantially in
the form of Exhibit A2 hereto. The Notes may have notations, legends or
endorsements required by law, stock exchange rule or usage. Each Note shall be
dated the date of its authentication. The Notes shall be in denominations of
$1,000 and integral multiples thereof. Notes sold to IAIs shall be in a minimum
principal amount of $250,000.

     The terms and provisions contained in the Notes shall constitute, and are
hereby expressly made, a part of this Supplemental Indenture, and the Company
and the Trustee, by their execution and delivery of this Supplemental Indenture,
expressly agree to such terms and provisions and to be bound thereby. However,
to the extent any provision of any Note conflicts with the express provisions of
this Supplemental Indenture, the provisions of this Supplemental Indenture shall
govern and be controlling.

     The Initial Notes issued on the date hereof will be (i) offered and sold by
the Company pursuant to the Purchase Agreement and (ii) resold initially only to
(A) IAIs in accordance with

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Regulation D, (B) QIBs in reliance on Rule 144A and (C) Persons other than U.S.
Persons (as defined in Regulation S) in reliance on Regulation S. Such Initial
Notes may thereafter be transferred to, among others, QIBs and purchasers in
reliance on Regulation S and, except as set forth below, IAIs in accordance with
Regulation D.

     The Company hereby designates The Depository Trust Company as the initial
Depositary for the Global Notes.

     (b)  GLOBAL NOTES. The Rule 144A Notes shall be issued initially in the
form of one or more notes in registered, global form (collectively, the "Rule
144A Global Note") and the Regulation S Notes shall be issued initially in the
form of one or more temporary notes in registered, global form (collectively,
the "Regulation S Global Note"), in each case without interest coupons and
bearing the Global Notes Legend and Restricted Notes Legend, which shall be
deposited on behalf of the purchasers of the Notes represented thereby with the
Notes Custodian, and registered in the name of the Depositary or a nominee of
the Depositary, duly executed by the Company and authenticated by the Trustee as
provided in the Indenture. One or more global securities in definitive, fully
registered form without interest coupons and bearing the Global Notes Legend and
the Restricted Notes Legend (collectively, the "IAI Global Note") shall also be
issued on the date of this Supplemental Indenture, deposited with the Notes
Custodian, and registered in the name of the Depositary or a nominee of the
Depositary, duly executed by the Company and authenticated by the Trustee as
provided in this Supplemental Indenture to accommodate transfers of beneficial
interests in the Notes to IAIs subsequent to the initial distribution.
Beneficial ownership interests in the Regulation S Global Note shall not be
exchangeable for interests in the Rule 144A Global Note, the IAI Global Note or
any other Note without a Restricted Notes Legend until the expiration of the
Restricted Period. The Rule 144A Global Note, the Regulation S Global Note and
the IAI Global Note are each referred to herein as a "Global Note" and are
collectively referred to herein as "Global Notes." The aggregate principal
amount of the Global Notes may from time to time be increased or decreased by
adjustments made on the records of the Trustee and the Depositary or its nominee
as hereinafter provided.

     (c)  BOOK-ENTRY PROVISIONS. This Section 2.3(c) shall apply only to a
Global Note deposited with or on behalf of the Depositary. The Company shall
execute and the Trustee shall, in accordance with this Section 2.3(c) and
pursuant to an order of the Company, authenticate and deliver initially one or
more Global Notes that (a) shall be registered in the name of the Depositary for
such Global Note or Global Notes or the nominee of such Depositary and (b) shall
be delivered by the Trustee to such Depositary or pursuant to such Depositary's
instructions or held by the Trustee as Notes Custodian.

     Participants shall have no rights under the Indenture with respect to any
Global Note held on their behalf by the Depositary or by the Trustee as Notes
Custodian or under such Global Note, and the Depositary may be treated by the
Company, the Trustee and any agent of the Company or the Trustee as the absolute
owner of such Global Note for all purposes whatsoever. Notwithstanding the
foregoing, nothing herein shall prevent the Company, the Trustee or any agent of
the Company or the Trustee from giving effect to any written certification,
proxy or other authorization furnished by the Depositary or impair, as between
the Depositary and its

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Participants, the operation of customary practices of such Depositary governing
the exercise of the rights of a holder of a beneficial interest in any Global
Note.

     (d)  DEFINITIVE NOTES. Except as provided in Section 2.5, owners of
beneficial interests in Global Notes will not be entitled to receive physical
delivery of certificated Notes.

     SECTION 2.4  TRANSFER AND EXCHANGE.

     (a)  TRANSFER AND EXCHANGE OF DEFINITIVE NOTES. When Definitive Notes are
presented to the Registrar with a request:

          (i)     to register the transfer of such Definitive Notes; or

          (ii)    to exchange such Definitive Notes for an equal principal
     amount of Definitive Notes of other authorized denominations, the Registrar
     shall register the transfer or make the exchange as requested if its
     reasonable requirements for such transaction are met; provided, however,
     that the Definitive Notes surrendered for transfer or exchange:

                  (A)  shall be duly endorsed or accompanied by a written
          instrument of transfer in form reasonably satisfactory to the Company
          and the Registrar, duly executed by the Holder thereof or his attorney
          duly authorized in writing; and

                  (B)  are accompanied by the following additional information
          and documents, as applicable:

                       (x) if such Definitive Notes are being delivered to the
                  Registrar by a Holder for registration in the name of such
                  Holder, without transfer, a certification from such Holder to
                  that effect (in the form set forth on the reverse side of the
                  Initial Note); or

                       (y) if such Definitive Notes are being transferred to the
                  Company, a certification to that effect (in the form set forth
                  on the reverse side of the Initial Note); or

                  (C)  if such Definitive Notes are being transferred pursuant
          to an exemption from registration in accordance with Rule 144 under
          the Securities Act or in reliance upon another exemption from the
          registration requirements of the Securities Act, (i) a certification
          to that effect (in the form set forth on the reverse side of the
          Initial Note) and (ii) if the Company so requests, an opinion of
          counsel or other evidence reasonably satisfactory to it as to the
          compliance with the restrictions set forth in the legend set forth in
          Section 2.4(e)(i).

     (b)  RESTRICTIONS ON TRANSFER OF A DEFINITIVE NOTE FOR A BENEFICIAL
INTEREST IN A GLOBAL NOTE. A Definitive Note may not be exchanged for a
beneficial interest in a Global Note except upon satisfaction of the
requirements set forth below. Upon receipt by the Trustee of a Definitive Note,
duly endorsed or accompanied by a written instrument of transfer in form
reasonably satisfactory to the Company and the Registrar, together with:

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          (i)     certification (in the form set forth on the reverse side of
     the Initial Note) that such Definitive Note is being transferred (A) to a
     QIB in accordance with Rule 144A, (B) to an IAI that has furnished to the
     Trustee a signed letter substantially in the form of Exhibit B hereto and,
     at the request of the Company, delivers an opinion of counsel reasonably
     acceptable to the Company stating that the proposed transfer is being made
     pursuant to an exemption from, or in a transacting not subject to, the
     registration requirements of the Securities Act or (C) outside the United
     States in an offshore transaction within the meaning of Regulation S and in
     compliance with Rule 904 under the Securities Act; and

          (ii)    written instructions directing the Trustee to make, or to
     direct the Notes Custodian to make, an adjustment on its books and records
     with respect to such Global Note to reflect an increase in the aggregate
     principal amount of the Notes represented by the Global Note, such
     instructions to contain information regarding the Depositary account to be
     credited with such increase, then the Trustee shall cancel such Definitive
     Note and cause, or direct the Notes Custodian to cause, in accordance with
     the standing instructions and procedures existing between the Depositary
     and the Notes Custodian, the aggregate principal amount of Notes
     represented by the Global Note to be increased by the aggregate principal
     amount of the Definitive Note to be exchanged and shall credit or cause to
     be credited to the account of the Person specified in such instructions a
     beneficial interest in the Global Note equal to the principal amount of the
     Definitive Note so canceled. If no Global Notes are then outstanding and
     the Global Note has not been previously exchanged for certificated
     securities pursuant to Section 2.5, the Company shall issue and the Trustee
     shall authenticate, upon receipt of a Company Order, a new Global Note in
     the appropriate principal amount.

     (c)  TRANSFER AND EXCHANGE OF GLOBAL NOTES.

          (i)     The transfer and exchange of Global Notes or beneficial
     interests therein shall be effected through the Depositary, in accordance
     with this Supplemental Indenture (including applicable restrictions on
     transfer set forth herein, if any) and the procedures of the Depositary
     therefor. A transferor of a beneficial interest in a Global Note shall
     deliver a written order given in accordance with the Depositary's
     procedures containing information regarding the participant account of the
     Depositary to be credited with a beneficial interest in such Global Note or
     another Global Note and such account shall be credited in accordance with
     such order with a beneficial interest in the applicable Global Note and the
     account of the Person making the transfer shall be debited by an amount
     equal to the beneficial interest in the Global Note being transferred.
     Transfers by an owner of a beneficial interest in an IAI Global Note or a
     Rule 144A Global Note to a transferee who takes delivery of such interest
     through a Regulation S Global Note, whether before or after the expiration
     of the Restricted Period, shall be made only upon receipt by the Trustee of
     a certification from the transferor to the effect that such transfer is
     being made in accordance with 903 or 904 of Regulation S or (if available)
     Rule 144 under the Securities Act and that, if such transfer is being made
     prior to the expiration of the Restricted Period, the interest transferred
     shall be held immediately thereafter through Euroclear or Clearstream.
     Transfers by an owner of a beneficial interest in a Rule 144A Global Note
     may be made to a transferee who takes delivery of such interest through an

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     IAI Global Note only if the transferee delivers to the Trustee a signed
     letter substantially in the form attached hereto as Exhibit B and, at the
     request of the Company, delivers an opinion of counsel reasonably
     acceptable to the Company stating that the proposed transfer is being made
     pursuant to an exemption from, or in a transaction not subject to, the
     registration requirements of the Securities Act.

          (ii)    If the proposed transfer is a transfer of a beneficial
     interest in one Global Note to a beneficial interest in another Global
     Note, the Registrar shall reflect on its books and records the date and an
     increase in the principal amount of the Global Note to which such interest
     is being transferred in an amount equal to the principal amount of the
     interest to be so transferred, and the Registrar shall reflect on its books
     and records the date and a corresponding decrease in the principal amount
     of Global Note from which such interest is being transferred.

          (iii)   Notwithstanding any other provisions of this Supplemental
     Indenture (other than the provisions set forth in Section 2.5), a Global
     Note may not be transferred as a whole except by the Depositary to a
     nominee of the Depositary or by a nominee of the Depositary to the
     Depositary or another nominee of the Depositary or by the Depositary or any
     such nominee to a successor Depositary or a nominee of such successor
     Depositary.

          (iv)    In the event that a Global Note is exchanged for Definitive
     Notes pursuant to Section 2.5 prior to the consummation of the Registered
     Exchange Offer or the effectiveness of the Shelf Registration Statement
     with respect to such Notes, such Notes may be exchanged only in accordance
     with such procedures as are substantially consistent with the provisions of
     this Section 2.4 (including the certification requirements set forth on the
     reverse of the Initial Notes intended to ensure that such transfers comply
     with Rule 144, Rule 144A, Regulation S or such other applicable exemption
     from registration under the Securities Act, as the case may be) and such
     other procedures as may from time to time be adopted by the Company.

     (d)  RESTRICTIONS ON TRANSFER OF REGULATION S GLOBAL NOTE.

          (i)     Prior to the expiration of the Restricted Period, interests in
     a Regulation S Global Note may only be held through Euroclear or
     Clearstream. During the Restricted Period, beneficial ownership interests
     in a Regulation S Global Note may only be sold, pledged or transferred
     through Euroclear or Clearstream in accordance with the Applicable
     Procedures and only (A) to the Company, (B) so long as such security is
     eligible for resale pursuant to Regulation D or Rule 144A, to a person whom
     the selling holder reasonably believes is an institutional accredited
     investor or a QIB that purchases for its own account or for the account of
     an institutional accredited investor or a QIB to whom notice is given that
     the resale, pledge or transfer is being made in reliance on Regulation D or
     Rule 144A, (C) in an offshore transaction in accordance with Regulation S,
     (D) pursuant to an exemption from registration under the Securities Act
     provided by Regulation D or Rule 144 (if applicable) under the Securities
     Act, (E) to an IAI purchasing for its own account, or for the account of
     such an IAI, in a minimum principal amount of Notes of $250,000 or (F)
     pursuant to an effective registration statement under

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     the Securities Act, in each case in accordance with any applicable
     securities laws of any state of the United States. Prior to the expiration
     of the Restricted Period, transfers by an owner of a beneficial interest in
     a Regulation S Global Note to a transferee who takes delivery of such
     interest through an IAI Global Note or Rule 144A Global Note shall be made
     only in accordance with the Applicable Procedures, pursuant to Rule 144 or
     144A of the Securities Act and upon receipt by the Trustee of a written
     certification from the transferor of the beneficial interest in the form
     provided on the reverse of the Initial Note to the effect that such
     transfer is being made (i) to a person whom the transferor reasonably
     believes is an institutional accredited investor or a QIB within the
     meaning of Regulation D or Rule 144A, respectively in a transaction meeting
     the requirements of Regulation D or 144A or (ii) an IAI purchasing for its
     own account, or for the account of such an IAI, in a minimum principal
     amount of the Notes of $250,000. Such written certification shall no longer
     be required after the expiration of the Restricted Period. In the case of a
     transfer of a beneficial interest in a Regulation S Global Note for an
     interest in a Rule 144A Global Note or an IAI Global Note, the transferee
     must furnish a signed letter substantially in the form of Exhibit B hereto
     and, at the request of the Company, deliver an opinion of counsel
     reasonably acceptable to the Company stating that the proposed transfer is
     being made pursuant to an exemption from, or in a transaction not subject
     to, the registration requirements of the Securities Act.

          (ii)    Upon the expiration of the Restricted Period, beneficial
     ownership interests in a Regulation S Global Note shall be transferable in
     accordance with applicable law and the other terms of the Indenture.

     (e)  LEGENDS FOR NOTES.

          (i)     Except as permitted by the following paragraphs (ii), (iii),
     (iv) or (vi), each Note certificate evidencing the Global Notes and the
     Definitive Notes (and all Notes issued in exchange therefor or in
     substitution thereof) shall bear a legend in substantially the following
     form (each defined term in the legend being defined as such for purposes of
     the legend only):

          THIS NOTE HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS
          AMENDED (THE "SECURITIES ACT"), AND ACCORDINGLY, MAY NOT BE OFFERED OR
          SOLD WITHIN THE UNITED STATES OR TO, OR FOR THE ACCOUNT OR BENEFIT OF,
          U.S. PERSONS EXCEPT AS SET FORTH IN THE FOLLOWING SENTENCE. BY ITS
          ACQUISITION HEREOF, THE HOLDER (1) REPRESENTS THAT (A) IT IS A
          "QUALIFIED INSTITUTIONAL BUYER" (AS DEFINED IN RULE 144A UNDER THE
          SECURITIES ACT), (B) IT IS AN INSTITUTIONAL "ACCREDITED INVESTOR" (AS
          DEFINED IN RULE 501(A)(1), (2), (3) OR (7) UNDER THE SECURITIES ACT)
          (AN "INSTITUTIONAL ACCREDITED INVESTOR"), OR (C) IT IS NOT A U.S.
          PERSON AND IS ACQUIRING THIS NOTE IN AN OFFSHORE TRANSACTION IN
          COMPLIANCE WITH RULE 904 UNDER THE SECURITIES ACT, (2) AGREES THAT IT
          WILL NOT, WITHIN THE TIME PERIOD REFERRED TO IN RULE 144(k) UNDER THE
          SECURITIES ACT AS IN EFFECT ON THE DATE OF THE TRANSFER OF THIS NOTE,

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          RESELL OR OTHERWISE TRANSFER THIS NOTE EXCEPT (A) TO THE ISSUER
          THEREOF OR ANY SUBSIDIARY THEREOF, (B) INSIDE THE UNITED STATES TO A
          QUALIFIED INSTITUTIONAL BUYER IN COMPLIANCE WITH RULE 144A UNDER THE
          SECURITIES ACT, (C) INSIDE THE UNITED STATES TO AN INSTITUTIONAL
          ACCREDITED INVESTOR THAT, PRIOR TO SUCH TRANSFER, FURNISHES TO THE
          TRUSTEE (OR A SUCCESSOR TRUSTEE, AS APPLICABLE), A SIGNED LETTER
          CONTAINING CERTAIN REPRESENTATIONS AND AGREEMENTS RELATING TO THE
          RESTRICTIONS ON TRANSFER OF THIS SECURITY (THE FORM OF WHICH LETTER
          CAN BE OBTAINED FROM THE TRUSTEE) AND, IF REQUESTED BY THE ISSUER, AN
          OPINION OF COUNSEL REASONABLY ACCEPTABLE TO THE ISSUER THEREOF TO THE
          EFFECT THAT THE TRANSFER IS BEING MADE PURSUANT TO AN EXEMPTION FROM,
          OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION REQUIREMENTS OF
          THE SECURITIES ACT, (D) OUTSIDE THE UNITED STATES IN AN OFFSHORE
          TRANSACTION IN COMPLIANCE WITH RULE 904 UNDER THE SECURITIES ACT, (E)
          PURSUANT TO THE EXEMPTION FROM REGISTRATION PROVIDED BY RULE 144 UNDER
          THE SECURITIES ACT (IF AVAILABLE) OR (F) PURSUANT TO AN EFFECTIVE
          REGISTRATION STATEMENT UNDER THE SECURITIES ACT, AND (3) AGREES THAT
          IT WILL DELIVER TO EACH PERSON TO WHOM THIS NOTE IS TRANSFERRED A
          NOTICE SUBSTANTIALLY TO THE EFFECT OF THIS LEGEND. IN CONNECTION WITH
          ANY TRANSFER OF THIS NOTE WITHIN THE TIME PERIOD REFERRED TO IN RULE
          144(k) UNDER THE SECURITIES ACT AFTER THE ORIGINAL ISSUANCE OF THE
          NOTES, THE HOLDER MUST TRANSFER AND SUBMIT THIS NOTE TO THE TRUSTEE.
          AS USED HEREIN, THE TERMS "OFFSHORE TRANSACTION," "UNITED STATES" AND
          "U.S. PERSON" HAVE THE MEANINGS GIVEN TO THEM BY REGULATION S UNDER
          THE SECURITIES ACT. THE INDENTURE CONTAINS PROVISIONS REQUIRING THE
          TRUSTEE TO REFUSE TO REGISTER ANY TRANSFER OF THIS NOTE IN VIOLATION
          OF THE FOREGOING RESTRICTIONS.

     Each Note evidencing a Global Note offered and sold to QIBs pursuant to
     Rule 144A shall bear a legend in substantially the following form:

          EACH PURCHASER OF THIS SECURITY IS HEREBY NOTIFIED THAT THE SELLER OF
          THIS SECURITY MAY BE RELYING ON THE EXEMPTION FROM THE PROVISIONS OF
          SECTION 5 OF THE SECURITIES ACT PROVIDED BY RULE 144A THEREUNDER.

     Each Definitive Note shall bear the following additional legend:

          IN CONNECTION WITH ANY TRANSFER, THE HOLDER WILL DELIVER TO THE
          REGISTRAR AND TRANSFER AGENT SUCH CERTIFICATES AND OTHER INFORMATION
          AS SUCH TRANSFER AGENT MAY

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          REASONABLY REQUIRE TO CONFIRM THAT THE TRANSFER COMPLIES WITH THE
          FOREGOING RESTRICTIONS.

          (ii)    Upon any sale or transfer of a Transfer Restricted Note that
     is a Definitive Note, the Registrar shall permit the Holder thereof to
     exchange such Transfer Restricted Note for a Definitive Note that does not
     bear the legends set forth above and rescind any restriction on the
     transfer of such Transfer Restricted Note if the Holder certifies in
     writing to the Registrar that its request for such exchange was made in
     reliance on Rule 144 (such certification to be in the form set forth on the
     reverse of the Initial Note).

          (iii)   After a transfer of any Initial Notes during the period of the
     effectiveness of a Shelf Registration Statement with respect to such
     Initial Notes, as the case may be, all requirements pertaining to the
     Restricted Notes Legend on such Initial Notes shall cease to apply and the
     requirements that any such Initial Notes be issued in global form shall
     continue to apply.

          (iv)    Upon the consummation of a Registered Exchange Offer with
     respect to the Initial Notes pursuant to which Holders of such Initial
     Notes are offered Exchange Notes in exchange for their Initial Notes, all
     requirements pertaining to Initial Notes that Initial Notes be issued in
     global form shall continue to apply, and Exchange Notes in global form
     without the Restricted Notes Legend shall be available to Holders that
     exchange such Initial Notes in such Registered Exchange Offer.

          (v)     Upon a sale or transfer after the expiration of the Restricted
     Period of any Initial Note acquired pursuant to Regulation S, all
     requirements that such Initial Note bear the Restricted Notes Legend shall
     cease to apply and the requirements requiring any such Initial Note be
     issued in global form shall continue to apply.

     (f)  CANCELLATION OR ADJUSTMENT OF GLOBAL NOTE. At such time as all
beneficial interests in a Global Note have either been exchanged for Definitive
Notes, transferred, redeemed, repurchased or canceled, such Global Note shall be
returned by the Depositary to the Trustee for cancellation or retained and
canceled by the Trustee. At any time prior to such cancellation, if any
beneficial interest in a Global Note is exchanged for Definitive Notes,
transferred in exchange for an interest in another Global Note, redeemed,
repurchased or canceled, the principal amount of Notes represented by such
Global Note shall be reduced and an adjustment shall be made on the books and
records of the Trustee (if it is then the Notes Custodian for such Global Note)
with respect to such Global Note, by the Trustee or the Notes Custodian, to
reflect such reduction.

     (g)  OBLIGATIONS WITH RESPECT TO TRANSFERS AND EXCHANGES OF NOTES.

          (i)     To permit registrations of transfers and exchanges, the
     Company shall execute and the Trustee shall authenticate, Definitive Notes
     and Global Notes at the Registrar's request.

          (ii)    No service charge shall be made for any registration of
     transfer or exchange, but the Company may require payment of a sum
     sufficient to cover any transfer tax, assessments, or similar governmental
     charge payable in connection therewith

                                       11
<Page>

     (other than any such transfer taxes, assessments or similar governmental
     charge payable upon exchange or transfer pursuant to Sections 9.6 or 11.6
     of the Indenture).

          (iii)   Prior to the due presentation for registration of transfer of
     any Note, the Company, the Trustee, the Paying Agent or the Registrar may
     deem and treat the person in whose name a Note is registered as the
     absolute owner of such Note for the purpose of receiving payment of
     principal of and interest on such Note and for all other purposes
     whatsoever, whether or not such Note is overdue, and none of the Company,
     the Trustee, the Paying Agent or the Registrar shall be affected by notice
     to the contrary.

          (iv)    The Company shall not be required to make and the Registrar
     need not register transfers or exchanges of Notes selected for redemption
     (except, in the case of Notes to be redeemed in part, the portion thereof
     not to be redeemed) or any Notes for a period of 15 days before the mailing
     of a notice of redemption of Notes to be redeemed.

          (v)     All Notes issued upon any transfer or exchange pursuant to the
     terms of this Supplemental Indenture shall evidence the same Debt and shall
     be entitled to the same benefits under the Indenture as the Notes
     surrendered upon such transfer or exchange.

     (h)  NO OBLIGATION OF THE TRUSTEE.

          (i)     The Trustee shall have no responsibility or obligation to any
     beneficial owner of a Global Note, a member of, or a participant in the
     Depositary or any other Person with respect to the accuracy of the records
     of the Depositary or its nominee or of any participant or member thereof,
     with respect to any ownership interest in the Notes or with respect to the
     delivery to any participant, member, beneficial owner or other Person
     (other than the Depositary) of any notice (including any notice of
     redemption or repurchase) or the payment of any amount, under or with
     respect to such Notes. All notices and communications to be given to the
     Holders and all payments to be made to Holders under the Notes shall be
     given or made only to the registered Holders (which shall be the Depositary
     or its nominee in the case of a Global Note). The rights of beneficial
     owners in any Global Note shall be exercised only through the Depositary
     subject to the applicable rules and procedures of the Depositary. The
     Trustee may rely and shall be fully protected in relying upon information
     furnished by the Depositary with respect to its members, participants and
     any beneficial owners.

          (ii)    The Trustee shall have no obligation or duty to monitor,
     determine or inquire as to compliance with any restrictions on transfer
     imposed under this Supplemental Indenture or under applicable law with
     respect to any transfer of any interest in any Note (including any
     transfers between or among Depositary participants, members or beneficial
     owners in any Global Note) other than to require delivery of such
     certificates and other documentation or evidence as are expressly required
     by, and to do so if and when expressly required by, the terms of this
     Supplemental Indenture, and to examine the same to determine substantial
     compliance as to form with the express requirements hereof.

                                       12
<Page>

     SECTION 2.5  DEFINITIVE NOTES.

     (a)  A Global Note deposited with the Depositary or with the Trustee as
Notes Custodian pursuant to Section 2.3 shall be transferred to the beneficial
owners thereof in the form of Definitive Notes in an aggregate principal amount
equal to the principal amount of such Global Note, in exchange for such Global
Note, only if such transfer complies with Section 2.4 and (i) the Company
notifies the Trustee that the Depositary, Euroclear or Clearstream is no longer
willing or able to act as a depositary or clearing system for the Notes or the
Depositary or the Depositary ceases to be a "clearing agency" registered under
the Exchange Act, and a successor depositary or clearing system is not appointed
by the Company within 90 days of such notice or cessation, (ii) the Company, in
its sole discretion, notifies the Trustee in writing that it elects to cause the
issuance of Definitive Notes under the Indenture, or (iii) upon the occurrence
and continuation of an Event of Default.

     (b)  Any Global Note that is transferable to the beneficial owners thereof
pursuant to this Section 2.5 shall be surrendered by the Depositary to the
Trustee, to be so transferred, in whole or from time to time in part, without
charge, and the Trustee shall authenticate and deliver, upon such transfer of
each portion of such Global Note, an equal aggregate principal amount of
Definitive Notes of authorized denominations. Any portion of a Global Note
transferred pursuant to this Section 2.5 shall be executed, authenticated and
delivered only in denominations of $1,000 of principal amount and any integral
multiple thereof and registered in such names as the Depositary shall direct.
Any certificated Initial Note in the form of a Definitive Note delivered in
exchange for an interest in the Global Note shall, except as otherwise provided
by Section 2.4, bear the Restricted Notes Legend.

     (c)  The registered Holder of a Global Note may grant proxies and otherwise
authorize any Person, including Participants and Persons that may hold interests
through Participants, to take any action which a Holder is entitled to take
under the Indenture or the Notes.

     (d)  In the event of the occurrence of any of the events specified in
Section 2.5(a)(i), (ii) or (iii), the Company will promptly make available to
the Trustee a reasonable supply of Definitive Notes in fully registered form
without interest coupons.

                                  ARTICLE THREE

                            MISCELLANEOUS PROVISIONS

     SECTION 3.1  RATIFICATION. The Indenture, as supplemented and amended by
this Supplemental Indenture, is in all respects hereby adopted, ratified and
confirmed.

     SECTION 3.2  COUNTERPARTS. This Supplemental Indenture may be executed in
any number of counterparts, each of which when so executed shall be deemed an
original, and all such counterparts shall together constitute but one and the
same instrument.

     SECTION 3.3  GOVERNING LAW. THIS SUPPLEMENTAL INDENTURE AND EACH SECURITY
SHALL BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE STATE OF
NEW YORK WITHOUT REGARD TO THE CHOICE OF LAW PRINCIPLES THEREOF.

                                       13
<Page>

                            [signature page follows]

                                       14
<Page>

     IN WITNESS WHEREOF, the parties hereto have caused this Supplemental
Indenture No. 1 to be duly executed as of the day and year first above written.

                                  HOSPIRA, INC.

                                  By: /s/ Terrence C. Kearney
                                      ----------------------------------------
                                      Name:  Terrence C. Kearney
                                      Title: Senior Vice President, Finance
                                             and Chief Financial Officer

                                  LASALLE BANK NATIONAL
                                      ASSOCIATION,
                                      as Trustee

                                  By: /s/ Wayne Evans
                                      ----------------------------------------
                                      Name:  Wayne Evans
                                      Title: First Vice President

                                       15
<Page>

                    EXHIBIT A1 - FORM OF 4.95% NOTE DUE 2009

 [INSERT APPROPRIATE LEGEND(S), PURSUANT TO SECTION 2.5(e)(i) OF SUPPLEMENTAL
                                   INDENTURE]

                                  HOSPIRA, INC.

                               4.95% NOTE DUE 2009

NO.                                                                            $
CUSIP NO.

     This Security is a Security in a global form within the meaning of the
Indenture and Supplemental Indenture hereinafter referred to and is registered
in the name of the Depository or a nominee of the Depository. This global
Security is exchangeable for Securities registered in the name of a Person other
than the Depository or its nominee only in the limited circumstances described
in the Indenture, and no transfer of this Security (other than a transfer of
this Security as a whole by the Depository to a nominee of the Depository or by
a nominee of the Depository to the Depository or another nominee of the
Depository) may be registered except in such limited circumstances.

     Unless this Security is presented by an authorized representative of The
Depository Trust Company (55 Water Street, New York, New York) to the issuer or
its agent for registration of transfer, exchange or payment, and any Security
issued upon registration of transfer of, or in exchange for, or in lieu of, this
Security is registered in the name of Cede & Co. or such other name as requested
by an authorized representative of The Depository Trust Company and any payment
hereon is made to Cede & Co., ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE
OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL since the registered owner hereof,
Cede & Co., has an interest herein.

<Page>

                                  HOSPIRA, INC.

     HOSPIRA, INC., a corporation duly organized and existing under the laws of
Delaware (herein called the "Company," which term includes any successor Person
under the Indenture and Supplemental Indenture hereinafter referred to), for
value received, hereby promises to pay to Cede & Co., as nominee for The
Depository Trust Company, or registered assigns, the principal sum of
Million Dollars ($     ) on June 15, 2009 and to pay interest thereon from June
15, 2004 or from the most recent Interest Payment Date to which interest has
been paid or duly provided for, semi-annually on June 15 and December 15 in each
year, commencing December 15, 2004, at the rate of 4.95% per annum, until the
principal hereof is paid or made available for payment. The interest so payable,
and punctually paid or duly provided for, on any Interest Payment Date will, as
provided in such Indenture, be paid to the Person in whose name this Security
(or one or more Predecessor Securities) is registered at the close of business
on the Regular Record Date for such interest, which shall be the June 1 or
December 1 (whether or not a Business Day), as the case may be, next preceding
such Interest Payment Date. Any such interest not so punctually paid or duly
provided for will forthwith cease to be payable to the Holder on such Regular
Record Date and may either be paid to the Person in whose name this Security (or
one or more Predecessor Securities) is registered at the close of business on a
Special Record Date for the payment of such Defaulted Interest to be fixed by
the Trustee, notice whereof shall be given to Holders of Securities of this
series not less than 10 days prior to such Special Record Date, or be paid at
any time in any other lawful manner not inconsistent with the requirements of
any securities exchange on which the Securities of this series may be listed,
and upon such notice as may be required by such exchange, all as more fully
provided in said Indenture.

     Payment of the principal of (and premium, if any) and any such interest on
this Security will be made at the office or agency of the Company maintained for
that purpose in Chicago, Illinois, in such coin or currency of the United States
of America as at the time of payment is legal tender for payment of public and
private debts; PROVIDED, HOWEVER, that at the option of the Company payment of
interest may be made by check mailed to the address of the Person entitled
thereto as such address shall appear in the Security Register.

     Reference is hereby made to the further provisions of this Security set
forth on the reverse hereof, which further provisions shall for all purposes
have the same effect as if set forth at this place.

     Unless the certificate of authentication hereon has been executed by the
Trustee referred to herein by manual signature, this Security shall not be
entitled to any benefit under the Indenture or be valid or obligatory for any
purpose.

<Page>

     IN WITNESS WHEREOF, the Company has caused this instrument to be duly
executed under its corporate seal.

Dated:     , 2004

                                           HOSPIRA, INC.

                                             By:
                                                 -------------------------------
                                             Name:
                                             Title:

Attest:

------------------

                     TRUSTEE'S CERTIFICATE OF AUTHENTICATION

     This is one of the Securities designated therein referred to in the
within-mentioned Indenture.

                                           LASALLE BANK NATIONAL
                                             ASSOCIATION,
                                             as Trustee

                                           By
                                              ----------------------------------
                                             Name:  Wayne Evans
                                             Title: First Vice President

<Page>

                          [FORM OF REVERSE OF SECURITY]

     This Security is one of a duly authorized issue of securities of the
Company (herein called the "Securities"), issued and to be issued in one or more
series under an Indenture, dated as of June 14 , 2004 (herein called the
"Indenture") and Supplemental Indenture No. 1, dated as of June 14, 2004 (herein
called the "Supplemental Indenture"), both between the Company and LaSalle Bank
National Association, as Trustee (herein called the "Trustee," which term
includes any successor trustee under the Indenture), to which Indenture and
Supplemental Indenture reference is hereby made for a statement of the
respective rights, limitations of rights, duties and immunities thereunder of
the Company, the Trustee and the Holders of the Securities and of the terms upon
which the Securities are, and are to be, authenticated and delivered. This
Security is one of the series designated on the face hereof, limited in
aggregate principal amount to $300,000,000.

     The Securities of this series may be redeemed at any time at the Company's
option, in whole or from time to time in part, at a redemption price equal to
the sum of (1) the principal amount of any Securities of this series being
redeemed plus accrued interest to the redemption date and (2) the Make-Whole
Amount (as defined below), if any.

     If the Company has given notice as provided in the Indenture and funds for
the redemption of any Securities of this series called for redemption have been
made available on the redemption date, such Securities will cease to bear
interest on the date fixed for redemption. Thereafter, the only right of the
Holders of such Securities will be to receive payment of the redemption price.

     The Company will give notice of any optional redemption to Holders at their
addresses, as shown in the Security Register for such Securities, not more than
60 nor less than 30 days prior to the date fixed for redemption. The notice of
redemption will specify, among other items, the redemption price and the
principal amount of the Securities of this series held by such Holder to be
redeemed.

     The Company will notify the Trustee at least 45 days prior to giving notice
of redemption (or such shorter period as is satisfactory to the Trustee) of the
aggregate principal amount of the Securities of this series to be redeemed and
their redemption date. If less than all of the Securities of this series are to
be redeemed, the Trustee shall select which Securities are to be redeemed in a
manner it deems to be fair and appropriate.

     "Make-Whole Amount" means the excess of (1) the aggregate present value, on
the redemption date, of the principal being redeemed or paid and the amount of
interest (exclusive of interest accrued to the date of redemption or accelerated
payment) that would have been payable if such redemption or accelerated payment
had not been made, over (2) the aggregate principal amount of the Securities of
this series being redeemed or paid. Net present value shall be determined by
discounting, on a semi-annual basis, such principal and interest at the
Reinvestment Rate (as defined below and as determined on the third business day
preceding the

<Page>

date such notice of redemption is given or declaration of acceleration is made)
from the respective dates on which such principal and interest would have been
payable if such redemption or accelerated payment had not been made.

     "Reinvestment Rate" means 0.15% plus the arithmetic mean of the yields
under the respective heading "Week Ending" published in the most recent
Statistical Release (as defined below) under the caption "Treasury Constant
Maturities" for the maturity (rounded to the nearest month) corresponding to the
remaining life to maturity, as of the payment date of the principal being
redeemed or paid. If no maturity exactly corresponds to such maturity, yields
for the two published maturities most closely corresponding to such maturity
shall be calculated pursuant to the immediately preceding sentence and the
Reinvestment Rate shall be interpolated or extrapolated from such yields on a
straight-line basis, rounding in each of such relevant periods to the nearest
month. For the purpose of calculating the Reinvestment Rate, the most recent
Statistical Release published prior to the date of determination of the
Make-Whole Amount shall be used.

     "Statistical Release" means the statistical release designated "H.15(519)"
or any successor publication which is published weekly by the Federal Reserve
System and which establishes yields on actively traded United States government
securities adjusted to constant maturities, or, if such statistical release is
not published at the time of any determination under the Indenture, then such
other reasonably comparable index which shall be designated by the Company.

     The Securities of this series do not provide for a sinking fund.

     If an Event of Default with respect to Securities of this series shall
occur and be continuing, the principal of the Securities of this series may be
declared due and payable in the manner and with the effect provided in the
Indenture.

     The Indenture contains provisions for defeasance at any time of the entire
indebtedness of this Security or certain restrictive covenants and Events of
Default with respect to this Security, in each case upon compliance with certain
conditions set forth therein.

     The Indenture permits, with certain exceptions as therein provided, the
amendment thereof and the modification of the rights and obligations of the
Company and the rights of the Holders of the Securities of each series to be
affected under the Indenture at any time by the Company and the Trustee with the
consent of the Holders of a majority in principal amount of the Securities at
the time Outstanding of each series to be affected. The Indenture also contains
provisions permitting the Holders of specified percentages in principal amount
of the Securities of each series at the time Outstanding, on behalf of the
Holders of all Securities of such series, to waive compliance by the Company
with certain provisions of the Indenture and certain past defaults under the
Indenture and their consequences. Any such consent or waiver by the Holder of
this Security shall be conclusive and binding upon such Holder and upon all
future Holders of this Security and of any Security issued upon the registration
of transfer hereof or in exchange herefor or in lieu hereof, whether or not
notation of such consent or waiver is made upon this Security.

<Page>

     No reference herein to the Indenture or Supplemental Indenture and no
provision of this Security or of the Indenture or Supplemental Indenture shall
alter or impair the obligation of the Company, which is absolute and
unconditional, to pay the principal of and any premium and interest on this
Security at the times, place and rate, and in the coin or currency, herein
prescribed.

     As provided in the Indenture and subject to certain limitations therein set
forth, the transfer of this Security is registerable in the Security Register,
upon surrender of this Security for registration of transfer at the office or
agency of the Company in any place where the principal of and any premium and
interest on this Security are payable, duly endorsed by, or accompanied by a
written instrument of transfer in form satisfactory to the Company and the
Security Registrar duly executed by, the Holder hereof or his attorney duly
authorized in writing, and thereupon one or more new Securities of this series
and of like tenor, of authorized denominations and for the same aggregate
principal amount, will be issued to the designated transferee or transferees.

     The Securities of this series are issuable only in registered form without
coupons in denominations of $1,000 and any integral multiple thereof. As
provided in the Indenture and Supplemental Indenture and subject to certain
limitations therein set forth, Securities of this series are exchangeable for a
like aggregate principal amount of Securities of this series and of like tenor
of a different authorized denomination, as requested by the Holder surrendering
the same.

     No service charge shall be made for any such registration of transfer or
exchange, but the Company may require payment of a sum sufficient to cover any
tax or other governmental charge payable in connection therewith.

     Prior to due presentment of this Security for registration of transfer, the
Company, the Trustee and any agent of the Company or the Trustee may treat the
Person in whose name this Security is registered as the owner hereof for all
purposes, whether or not this Security be overdue, and neither the Company, the
Trustee nor any such agent shall be affected by notice to the contrary.

     All terms used in this Security which are defined in the Indenture and
Supplemental Indenture shall have the meanings assigned to them in the Indenture
and Supplemental Indenture.

     This Security is a Book-Entry Security within the meaning of the Indenture
hereinafter referred to and is registered in the name of a Depository or a
nominee of a Depository. This Security is exchangeable for Securities registered
in the name of a person other than the Depository or its nominee only in the
limited circumstances described in the Indenture and may not be transferred
except as a whole by the Depository to a nominee of the Depository or by a
nominee of the Depository to the Depository or another nominee of the
Depository.

                                    *  *  *

<Page>

                    CERTIFICATE TO BE DELIVERED UPON EXCHANGE
                    OR REGISTRATION OF TRANSFER OF SECURITIES

     This Certificate relates to $_____________ principal amount of Securities
held in (check applicable space) ___ book-entry or ___ definitive form by
_________________________ (the "Transferor").

The Transferor (check one box below):

     has requested the Trustee by written order to deliver in exchange for its
     beneficial interest in the global Security held by the Depositary a
     Security or Securities in definitive, registered form of authorized
     denominations in an aggregate principal amount equal to its beneficial
     interest in such global Security (or the portion thereof indicated above);
     or

     has requested the Trustee by written order to exchange or register the
     transfer of a Security or Securities.

     In connection with any transfer of any of the Securities evidenced by this
certificate occurring prior to the expiration of the period referred to in Rule
144(k) under the Securities Act of 1933, the undersigned confirms that such
Securities are being transferred in accordance with its terms:

CHECK ONE BOX BELOW

     (1)   / /    to the Company; or

     (2)   / /    pursuant to an effective registration statement under the
                  Securities Act of 1933; or

     (3)   / /    inside the United States to a "qualified institutional buyer"
                  (as defined in Rule 144A under the Securities Act of 1933)
                  that purchases for its own account or for the account of a
                  qualified institutional buyer to whom notice is given that
                  such transfer is being made in reliance on Rule 144A, in each
                  case pursuant to and in compliance with Rule 144A under the
                  Securities Act of 1933; or

     (4)   / /    outside the United States in an offshore transaction within
                  the meaning of Regulation S under the Securities Act in
                  compliance with Rule 904 under the Securities Act of 1933; or

     (5)   / /    to an institutional "accredited investor" (as defined in Rule
                  501(a)(1), (2), (3) or (7) under the Securities Act of 1933)
                  that has furnished to the Trustee a signed letter containing
                  certain representations and agreements; or

     (6)   / /    pursuant to another available exemption from registration
                  provided by Rule 144 under the Securities Act of 1933.

<Page>

     Prior to the expiration of the period referred to in Rule 144(k), unless
one of the boxes is checked, the Trustee will refuse to register any of the
Securities evidenced by this certificate in the name of any Person other than
the registered holder thereof; provided, however, that if box (4), (5) or (6) is
checked, the Trustee may require, prior to registering any such transfer of the
Securities, such legal opinions, certifications and other information
satisfactory to the Company and the Trustee to confirm that such transfer is
being made pursuant to an exemption from, or in a transaction not subject to,
the registration requirements of the Securities Act of 1933.

                                           ------------------------------
                                           [INSERT NAME OF TRANSFEROR]

Dated:
      -------------
       By:-------------------------------

<Page>

                              SCHEDULE OF EXCHANGES

     The following exchanges of a part of this Book-Entry Security have been
made:

<Table>
<Caption>
                                           Amount of increase in    Principal Amount of this         Signature of
               Amount of decrease in        Principal Amount of        Book-Entry Security       authorized signatory
 Date of        Principal Amount of           this Book-Entry        following such decrease         of Trustee or
Exchange     this Book-Entry Security            Security                (or increase)            Security Custodian
<S>          <C>                           <C>                      <C>                          <C>

</Table>

<Page>

                                 ASSIGNMENT FORM

To assign this Security, fill in the form below:
I or we assign and transfer this Security to

______________________________________________________________________
          (Print or type assignee's name, address and zip code)

______________________________________________________________________
               (Insert assignee's soc. sec. or tax I.D. No.)

and irrevocably appoint _____________________________________agent to transfer
this Security on the books of the Company. The agent may substitute another to
act for him.

Date:                        Your Signature:
     -----------------------                -------------------------------

______________________________________________________________________________

     Sign exactly as your name appears on the other side of this Security.

<Page>

                    EXHIBIT A2 - FORM OF 5.90% NOTE DUE 2014

 [INSERT APPROPRIATE LEGEND(S), PURSUANT TO SECTION 2.5(e)(i) OF SUPPLEMENTAL
                                   INDENTURE]

                                  HOSPIRA, INC.

                               5.90% NOTE DUE 2014

NO.                                                                            $
CUSIP NO.

     This Security is a Security in a global form within the meaning of the
Indenture and Supplemental Indenture hereinafter referred to and is registered
in the name of the Depository or a nominee of the Depository. This global
Security is exchangeable for Securities registered in the name of a Person other
than the Depository or its nominee only in the limited circumstances described
in the Indenture, and no transfer of this Security (other than a transfer of
this Security as a whole by the Depository to a nominee of the Depository or by
a nominee of the Depository to the Depository or another nominee of the
Depository) may be registered except in such limited circumstances.

     Unless this Security is presented by an authorized representative of The
Depository Trust Company (55 Water Street, New York, New York) to the issuer or
its agent for registration of transfer, exchange or payment, and any Security
issued upon registration of transfer of, or in exchange for, or in lieu of, this
Security is registered in the name of Cede & Co. or such other name as requested
by an authorized representative of The Depository Trust Company and any payment
hereon is made to Cede & Co., ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE
OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL since the registered owner hereof,
Cede & Co., has an interest herein.

<Page>

                                  HOSPIRA, INC.

     HOSPIRA, INC., a corporation duly organized and existing under the laws of
Delaware (herein called the "Company," which term includes any successor Person
under the Indenture and Supplemental Indenture hereinafter referred to), for
value received, hereby promises to pay to Cede & Co., as nominee for The
Depository Trust Company, or registered assigns, the principal sum of
Million Dollars ($      ) on June 15 , 2014 and to pay interest thereon from
June 15, 2004 or from the most recent Interest Payment Date to which interest
has been paid or duly provided for, semi-annually on June 15 and December 15 in
each year, commencing December 15, 2004, at the rate of 5.90% per annum, until
the principal hereof is paid or made available for payment. The interest so
payable, and punctually paid or duly provided for, on any Interest Payment Date
will, as provided in such Indenture, be paid to the Person in whose name this
Security (or one or more Predecessor Securities) is registered at the close of
business on the Regular Record Date for such interest, which shall be the June 1
or December 1 (whether or not a Business Day), as the case may be, next
preceding such Interest Payment Date. Any such interest not so punctually paid
or duly provided for will forthwith cease to be payable to the Holder on such
Regular Record Date and may either be paid to the Person in whose name this
Security (or one or more Predecessor Securities) is registered at the close of
business on a Special Record Date for the payment of such Defaulted Interest to
be fixed by the Trustee, notice whereof shall be given to Holders of Securities
of this series not less than 10 days prior to such Special Record Date, or be
paid at any time in any other lawful manner not inconsistent with the
requirements of any securities exchange on which the Securities of this series
may be listed, and upon such notice as may be required by such exchange, all as
more fully provided in said Indenture.

     Payment of the principal of (and premium, if any) and any such interest on
this Security will be made at the office or agency of the Company maintained for
that purpose in Chicago, Illinois, in such coin or currency of the United States
of America as at the time of payment is legal tender for payment of public and
private debts; PROVIDED, HOWEVER, that at the option of the Company payment of
interest may be made by check mailed to the address of the Person entitled
thereto as such address shall appear in the Security Register.

     Reference is hereby made to the further provisions of this Security set
forth on the reverse hereof, which further provisions shall for all purposes
have the same effect as if set forth at this place.

     Unless the certificate of authentication hereon has been executed by the
Trustee referred to herein by manual signature, this Security shall not be
entitled to any benefit under the Indenture or be valid or obligatory for any
purpose.

<Page>

     IN WITNESS WHEREOF, the Company has caused this instrument to be duly
executed under its corporate seal.

Dated:     , 2004

                                            HOSPIRA, INC.

                                              By:
                                                 -------------------------------
                                              Name:
                                              Title:

Attest:

--------------------

                     TRUSTEE'S CERTIFICATE OF AUTHENTICATION

     This is one of the Securities designated therein referred to in the
within-mentioned Indenture.

                                            LASALLE BANK NATIONAL
                                              ASSOCIATION,
                                              as Trustee

                                            By
                                               ---------------------------------
                                               Name:  Wayne Evans
                                               Title: First Vice President

<Page>

                          [FORM OF REVERSE OF SECURITY]

     This Security is one of a duly authorized issue of securities of the
Company (herein called the "Securities"), issued and to be issued in one or more
series under an Indenture, dated as of June 14, 2004 (herein called the
"Indenture") and Supplemental Indenture No. 1, dated as of June 14, 2004 (herein
called the "Supplemental Indenture"), both between the Company and LaSalle Bank
National Association, as Trustee (herein called the "Trustee," which term
includes any successor trustee under the Indenture), to which Indenture and
Supplemental Indenture reference is hereby made for a statement of the
respective rights, limitations of rights, duties and immunities thereunder of
the Company, the Trustee and the Holders of the Securities and of the terms upon
which the Securities are, and are to be, authenticated and delivered. This
Security is one of the series designated on the face hereof, limited in
aggregate principal amount to $400,000,000.

     The Securities of this series may be redeemed at any time at the Company's
option, in whole or from time to time in part, at a redemption price equal to
the sum of (1) the principal amount of any Securities of this series being
redeemed plus accrued interest to the redemption date and (2) the Make-Whole
Amount (as defined below), if any.

     If the Company has given notice as provided in the Indenture and funds for
the redemption of any Securities of this series called for redemption have been
made available on the redemption date, such Securities will cease to bear
interest on the date fixed for redemption. Thereafter, the only right of the
Holders of such Securities will be to receive payment of the redemption price.

     The Company will give notice of any optional redemption to Holders at their
addresses, as shown in the Security Register for such Securities, not more than
60 nor less than 30 days prior to the date fixed for redemption. The notice of
redemption will specify, among other items, the redemption price and the
principal amount of the Securities of this series held by such Holder to be
redeemed.

     The Company will notify the Trustee at least 45 days prior to giving notice
of redemption (or such shorter period as is satisfactory to the Trustee) of the
aggregate principal amount of the Securities of this series to be redeemed and
their redemption date. If less than all of the Securities of this series are to
be redeemed, the Trustee shall select which Securities are to be redeemed in a
manner it deems to be fair and appropriate.

     "Make-Whole Amount" means the excess of (1) the aggregate present value, on
the redemption date, of the principal being redeemed or paid and the amount of
interest (exclusive of interest accrued to the date of redemption or accelerated
payment) that would have been payable if such redemption or accelerated payment
had not been made, over (2) the aggregate principal amount of the Securities of
this series being redeemed or paid. Net present value shall be determined by
discounting, on a semi-annual basis, such principal and interest at the
Reinvestment Rate (as defined below and as determined on the third business day
preceding the

<Page>

date such notice of redemption is given or declaration of acceleration is made)
from the respective dates on which such principal and interest would have been
payable if such redemption or accelerated payment had not been made.

     "Reinvestment Rate" means 0.20% plus the arithmetic mean of the yields
under the respective heading "Week Ending" published in the most recent
Statistical Release (as defined below) under the caption "Treasury Constant
Maturities" for the maturity (rounded to the nearest month) corresponding to the
remaining life to maturity, as of the payment date of the principal being
redeemed or paid. If no maturity exactly corresponds to such maturity, yields
for the two published maturities most closely corresponding to such maturity
shall be calculated pursuant to the immediately preceding sentence and the
Reinvestment Rate shall be interpolated or extrapolated from such yields on a
straight-line basis, rounding in each of such relevant periods to the nearest
month. For the purpose of calculating the Reinvestment Rate, the most recent
Statistical Release published prior to the date of determination of the
Make-Whole Amount shall be used.

     "Statistical Release" means the statistical release designated "H.15(519)"
or any successor publication which is published weekly by the Federal Reserve
System and which establishes yields on actively traded United States government
securities adjusted to constant maturities, or, if such statistical release is
not published at the time of any determination under the Indenture, then such
other reasonably comparable index which shall be designated by the Company.

     The Securities of this series do not provide for a sinking fund.

     If an Event of Default with respect to Securities of this series shall
occur and be continuing, the principal of the Securities of this series may be
declared due and payable in the manner and with the effect provided in the
Indenture.

     The Indenture contains provisions for defeasance at any time of the entire
indebtedness of this Security or certain restrictive covenants and Events of
Default with respect to this Security, in each case upon compliance with certain
conditions set forth therein.

     The Indenture permits, with certain exceptions as therein provided, the
amendment thereof and the modification of the rights and obligations of the
Company and the rights of the Holders of the Securities of each series to be
affected under the Indenture at any time by the Company and the Trustee with the
consent of the Holders of a majority in principal amount of the Securities at
the time Outstanding of each series to be affected. The Indenture also contains
provisions permitting the Holders of specified percentages in principal amount
of the Securities of each series at the time Outstanding, on behalf of the
Holders of all Securities of such series, to waive compliance by the Company
with certain provisions of the Indenture and certain past defaults under the
Indenture and their consequences. Any such consent or waiver by the Holder of
this Security shall be conclusive and binding upon such Holder and upon all
future Holders of this Security and of any Security issued upon the registration
of transfer hereof or in exchange herefor or in lieu hereof, whether or not
notation of such consent or waiver is made upon this Security.

<Page>

     No reference herein to the Indenture or Supplemental Indenture and no
provision of this Security or of the Indenture or Supplemental Indenture shall
alter or impair the obligation of the Company, which is absolute and
unconditional, to pay the principal of and any premium and interest on this
Security at the times, place and rate, and in the coin or currency, herein
prescribed.

     As provided in the Indenture and subject to certain limitations therein set
forth, the transfer of this Security is registerable in the Security Register,
upon surrender of this Security for registration of transfer at the office or
agency of the Company in any place where the principal of and any premium and
interest on this Security are payable, duly endorsed by, or accompanied by a
written instrument of transfer in form satisfactory to the Company and the
Security Registrar duly executed by, the Holder hereof or his attorney duly
authorized in writing, and thereupon one or more new Securities of this series
and of like tenor, of authorized denominations and for the same aggregate
principal amount, will be issued to the designated transferee or transferees.

     The Securities of this series are issuable only in registered form without
coupons in denominations of $1,000 and any integral multiple thereof. As
provided in the Indenture and Supplemental Indenture and subject to certain
limitations therein set forth, Securities of this series are exchangeable for a
like aggregate principal amount of Securities of this series and of like tenor
of a different authorized denomination, as requested by the Holder surrendering
the same.

     No service charge shall be made for any such registration of transfer or
exchange, but the Company may require payment of a sum sufficient to cover any
tax or other governmental charge payable in connection therewith.

     Prior to due presentment of this Security for registration of transfer, the
Company, the Trustee and any agent of the Company or the Trustee may treat the
Person in whose name this Security is registered as the owner hereof for all
purposes, whether or not this Security be overdue, and neither the Company, the
Trustee nor any such agent shall be affected by notice to the contrary.

     All terms used in this Security which are defined in the Indenture and
Supplemental Indenture shall have the meanings assigned to them in the Indenture
and Supplemental Indenture.

     This Security is a Book-Entry Security within the meaning of the Indenture
hereinafter referred to and is registered in the name of a Depository or a
nominee of a Depository. This Security is exchangeable for Securities registered
in the name of a person other than the Depository or its nominee only in the
limited circumstances described in the Indenture and may not be transferred
except as a whole by the Depository to a nominee of the Depository or by a
nominee of the Depository to the Depository or another nominee of the
Depository.

                                    *  *  *

<Page>

                    CERTIFICATE TO BE DELIVERED UPON EXCHANGE
                    OR REGISTRATION OF TRANSFER OF SECURITIES

     This Certificate relates to $_____________ principal amount of Securities
held in (check applicable space) ___ book-entry or ___ definitive form by
_________________________ (the "Transferor").

The Transferor (check one box below):

     has requested the Trustee by written order to deliver in exchange for its
     beneficial interest in the global Security held by the Depositary a
     Security or Securities in definitive, registered form of authorized
     denominations in an aggregate principal amount equal to its beneficial
     interest in such global Security (or the portion thereof indicated above);
     or

     has requested the Trustee by written order to exchange or register the
     transfer of a Security or Securities.

     In connection with any transfer of any of the Securities evidenced by this
certificate occurring prior to the expiration of the period referred to in Rule
144(k) under the Securities Act of 1933, the undersigned confirms that such
Securities are being transferred in accordance with its terms:

CHECK ONE BOX BELOW

     (1)   / /    to the Company; or

     (2)   / /    pursuant to an effective registration statement under the
                  Securities Act of 1933; or

     (3)   / /    inside the United States to a "qualified institutional buyer"
                  (as defined in Rule 144A under the Securities Act of 1933)
                  that purchases for its own account or for the account of a
                  qualified institutional buyer to whom notice is given that
                  such transfer is being made in reliance on Rule 144A, in each
                  case pursuant to and in compliance with Rule 144A under the
                  Securities Act of 1933; or

     (4)   / /    outside the United States in an offshore transaction within
                  the meaning of Regulation S under the Securities Act in
                  compliance with Rule 904 under the Securities Act of 1933; or

     (5)   / /    to an institutional "accredited investor" (as defined in Rule
                  501(a)(1), (2), (3) or (7) under the Securities Act of 1933)
                  that has furnished to the Trustee a signed letter containing
                  certain representations and agreements; or

     (6)   / /    pursuant to another available exemption from registration
                  provided by Rule 144 under the Securities Act of 1933.

<Page>

     Prior to the expiration of the period referred to in Rule 144(k), unless
one of the boxes is checked, the Trustee will refuse to register any of the
Securities evidenced by this certificate in the name of any Person other than
the registered holder thereof; provided, however, that if box (4), (5) or (6) is
checked, the Trustee may require, prior to registering any such transfer of the
Securities, such legal opinions, certifications and other information
satisfactory to the Company and the Trustee to confirm that such transfer is
being made pursuant to an exemption from, or in a transaction not subject to,
the registration requirements of the Securities Act of 1933.

                                           ------------------------------
                                           [INSERT NAME OF TRANSFEROR]

Dated:
       --------------
       By:
           ------------------------

<Page>

                              SCHEDULE OF EXCHANGES

     The following exchanges of a part of this Book-Entry Security have been
made:

<Table>
<Caption>
                                           Amount of increase in    Principal Amount of this         Signature of
               Amount of decrease in        Principal Amount of        Book-Entry Security       authorized signatory
 Date of        Principal Amount of           this Book-Entry        following such decrease         of Trustee or
Exchange     this Book-Entry Security            Security                (or increase)            Security Custodian
<S>          <C>                           <C>                      <C>                          <C>

</Table>

<Page>

                                 ASSIGNMENT FORM

To assign this Security, fill in the form below:
I or we assign and transfer this Security to

_________________________________________________________________________
          (Print or type assignee's name, address and zip code)

_________________________________________________________________________
               (Insert assignee's soc. sec. or tax I.D. No.)

and irrevocably appoint _____________________________________agent to transfer
this Security on the books of the Company. The agent may substitute another to
act for him.

Date:                        Your Signature:
      ----------------------                --------------------------------

______________________________________________________________________________
     Sign exactly as your name appears on the other side of this Security.

<Page>

                                    EXHIBIT B

      FORM OF LETTER TO BE DELIVERED BY INSTITUTIONAL ACCREDITED INVESTORS

Hospira, Inc.
275 N. Field Drive
Lake Forest, Illinois 60064

LaSalle Bank National Association
Corporate Trust Services Division
135 S. LaSalle Street, Suite 1960
Chicago, IL 60603

Dear Sirs and Mesdames:

         We are delivering this letter in connection with a request to a
transfer of $      principal amount of the [ % Notes due 20 ] [ % Notes due 20 ]
(the "Securities") of Hospira, Inc., a Delaware corporation (the "Company").

     We hereby confirm that:

      (i)    we are an institutional "accredited investor" within the meaning of
          Rule 501(a) (1), (2), (3) or (7) under the Securities Act of 1933, as
          amended (the "Securities Act") (an "institutional accredited
          investor");

      (ii)   any purchase of the Securities by us will be for our own account or
          for the account of one or more other institutional accredited
          investors for which we exercise sole investment discretion;

      (iii)  in the event that we purchase any of the Securities, we will
          acquire % Notes due 20 in an aggregate principal amount of not less
          than $250,000 and % Notes due 20 in an aggregate principal amount of
          not less than $250,000, in each case for our own account or for any
          separate account for which we are acting;

      (iv)   we have such knowledge and experience in financial and business
          matters that we are capable of evaluating the merits and risks of
          purchasing the Securities;

      (v)    we are not acquiring the Securities with a view to, or for offer or
          sale in connection with, any distribution in violation of the
          Securities Act; provided that the disposition of our property and the
          property of any accounts for which we are acquiring Securities shall
          remain at all times within our and their control; and

      (vi)   we have received a copy of the offering memorandum relating to the
          offering of the Securities and acknowledge that we have had access to
          such financial and other information, and have been afforded the
          opportunity to ask such questions of representatives of the Company
          and receive answers thereto, as we deem necessary in connection with
          our decision to purchase the Securities.

         We understand that the Securities are being offered in a transaction
not involving any public offering within the United States within the meaning of
the Securities Act and that the Securities have not been registered under the
Securities Act, and we agree, on our own behalf and on behalf of each account
for which we acquire any Securities, that if in the future we decide to offer,
resell, pledge or otherwise transfer such Securities, such Securities may be
offered, resold, pledged or otherwise transferred only (i) to the Company or any
of its subsidiaries, (ii) to a person whom we reasonably believe is a "qualified
institutional buyer" (as defined in Rule 144A under the Securities Act), (iii)
to a person who we reasonably believe is an institutional accredited investor
within the meaning of Rule

<Page>

501(a) (1), (2), (3) or (7) under the Securities Act of 1933 in a transaction in
which the institutional accredited investor, prior to the transfer, furnishes to
the trustee a signed letter containing certain representations and agreements
relating to the restrictions on transfer of the Securities (the form of which
letter can be obtained from the trustee for the Securities) and, if requested by
the Company, an opinion of counsel reasonably acceptable to the Company to the
effect that the transfer is being made pursuant to an exemption from, or in a
transaction not subject to, the registration requirements of the Securities Act,
(iv) outside the United States in a transaction in accordance with Rule 904
under the Securities Act, (v) pursuant to an exemption from registration
provided by Rule 144 under the Securities Act (if available) or (vi) pursuant to
an effective registration statement under the Securities Act, in each of cases
(i) through (vi) in accordance with any applicable Securities laws of any state
of the United States or any other applicable jurisdiction. We understand that,
prior to any transfer referred to in clause (iii), (iv) or (v) of the preceding
sentence, we must furnish to the trustee for the Securities such certifications,
legal opinions and other information as the Company may reasonably require to
confirm that such transfer is being made pursuant to an exemption from, or in a
transaction not subject to, the registration requirements of the Securities Act.

         We acknowledge that you, the Company and others will rely upon our
confirmations, acknowledgments and agreements set forth herein, and we agree to
notify you promptly in writing if any of our representations or warranties
herein ceases to be accurate and complete.

     THIS LETTER SHALL BE GOVERNED BY, AND CONSTRUED IN ACCORDANCE WITH, THE
LAWS OF THE STATE OF NEW YORK, WITHOUT REGARD TO PRINCIPLES OF CONFLICTS OF
LAWS.

                                        ------------------------------------
                                            (Name of Transferee)

                                        By:
                                           ---------------------------------
                                           Name:
                                           Title:
                                           Address:

Date:<Page>

================================================================================
                                                                     Exhibit 4.4

                          REGISTRATION RIGHTS AGREEMENT

                               Dated June 14, 2004

                                     Between

                                  HOSPIRA, INC.

                                       And

                        MORGAN STANLEY & CO. INCORPORATED
                              ABN AMRO INCORPORATED
                          CITIGROUP GLOBAL MARKETS INC

================================================================================

<Page>

                          REGISTRATION RIGHTS AGREEMENT

          THIS REGISTRATION RIGHTS AGREEMENT (the "Agreement") is made and
entered into as of June 14, 2004, by and among Hospira, Inc., a Delaware
corporation (the "Company"), and the several initial purchasers named in
Schedule I hereto (the "Initial Purchasers").

          This Agreement is made pursuant to the Purchase Agreement dated June
7, 2004, between the Company and the Initial Purchasers (the "Purchase
Agreement"), which provides for the sale by the Company to the Initial
Purchasers of (i) $300,000,000 principal amount of its 4.95% Notes Due 2009 (the
"4.95% Notes") and (ii) $400,000,000 principal amount of its 5.90% Notes Due
2014 (the "5.90% Notes," and together with the 4.95% Notes, the "Securities").
In order to induce the Initial Purchasers to enter into the Purchase Agreement,
the Company has agreed to provide to the Initial Purchasers and their direct and
indirect transferees the registration rights with respect to the Securities set
forth in this Agreement. The execution of this Agreement is a condition to the
closing under the Purchase Agreement.

          In consideration of the foregoing, the parties hereto agree as
follows:

          1.      DEFINITIONS.

          As used in this Agreement, the following capitalized defined terms
shall have the following meanings:

          "1933 ACT" shall mean the Securities Act of 1933, as amended from time
to time.

          "1934 ACT" shall mean the Securities Exchange Act of 1934, as amended
from time to time.

          "BASE INTEREST" shall mean the interest that would otherwise accrue on
the Securities under the terms thereof and the applicable Indenture, without
giving effect to the provisions of this Agreement.

          "CLOSING DATE" shall mean the Closing Date as defined in the Purchase
Agreement.

          "COMPANY" shall have the meaning set forth in the preamble and shall
also include the Company's successors.

          "EXCHANGE DATES" shall have the meaning set forth in Section 2(a)(ii)
hereof.

          "EXCHANGE OFFER" shall mean the exchange offer by the Company of
Exchange Securities for Registrable Securities pursuant to Section 2(a) hereof.

<Page>

          "EXCHANGE OFFER REGISTRATION" shall mean a registration under the 1933
Act effected pursuant to Section 2(a) hereof.

          "EXCHANGE OFFER REGISTRATION STATEMENT" shall mean an exchange offer
registration statement on Form S-4 (or, if applicable, on another appropriate
form) and all amendments and supplements to such registration statement, in each
case including the Prospectus contained therein, all exhibits thereto and all
material incorporated by reference therein.

          "EXCHANGE SECURITIES" shall mean the debt securities issued by the
Company to be offered to Holders in exchange for Securities pursuant to the
Exchange Offer or otherwise pursuant to a registration of securities containing
terms identical to the Securities for which they are exchanged, except that (i)
interest thereon shall accrue from the last date on which interest was paid on
the Securities or, if no such interest has been paid, from the date of issuance
of the Securities, (ii) the Exchange Securities will not contain terms with
respect to transfer restrictions, and (iii) certain provisions relating to an
increase in the stated rate of interest on the Securities shall be eliminated.

          "HOLDER" shall mean each Initial Purchaser, for so long as it owns any
Registrable Securities, and each of its successors, assigns and direct and
indirect transferees who become registered owners of Registrable Securities
under the Indenture; PROVIDED that for purposes of Sections 4 and 5 of this
Agreement, the term "Holder" shall include Participating Broker-Dealers (as
defined in Section 4(a)).

          "INDENTURE" shall mean the Indenture relating to the Securities dated
as of June 14, 2004 between the Company and LaSalle Bank National Association,
as trustee, and as the same may be amended from time to time in accordance with
the terms thereof, as supplemented by a First Supplemental Indenture dated June
14, 2004 (the "Supplemental Indenture") between the Company and the Trustee.

          "INITIAL PURCHASERS" shall have the meaning set forth in the preamble.

          "MAJORITY HOLDERS" shall mean the Holders of a majority of the
aggregate principal amount of outstanding Registrable Securities; PROVIDED that
whenever the consent or approval of Holders of a specified percentage of
Registrable Securities is required hereunder, Registrable Securities held by the
Company or any of its affiliates (as such term is defined in Rule 405 under the
1933 Act) (other than the Initial Purchasers or subsequent Holders of
Registrable Securities if such subsequent holders are deemed to be such
affiliates solely by reason of their holding of such Registrable Securities)
shall not be counted in determining whether such consent or approval was given
by the Holders of such required percentage or amount.

          "PARTICIPATING BROKER-DEALER" shall have the meaning set forth in
Section 4(a) hereof.

          "PERSON" shall mean an individual, partnership, limited liability
company, corporation, trust or unincorporated organization, or a government or
agency or political subdivision thereof.

                                        2
<Page>

          "PROSPECTUS" shall mean the prospectus included in a Registration
Statement, including any preliminary prospectus, and any such prospectus as
amended or supplemented by any prospectus supplement, including a prospectus
supplement with respect to the terms of the offering of any portion of the
Registrable Securities covered by a Shelf Registration Statement, and by all
other amendments and supplements to such prospectus, and in each case including
all material incorporated by reference therein.

          "PURCHASE AGREEMENT" shall have the meaning set forth in the preamble.

          "REGISTRABLE SECURITIES" shall mean the Securities; PROVIDED, HOWEVER,
that the Securities shall cease to be Registrable Securities (i) when a
Registration Statement with respect to such Securities shall have been declared
effective under the 1933 Act and such Securities shall have been disposed of
pursuant to such Registration Statement, (ii) when such Securities have been
sold to the public pursuant to Rule 144(k) (or any similar provision then in
force, but not Rule 144A) under the 1933 Act or (iii) when such Securities shall
have ceased to be outstanding.

          "REGISTRATION DEFAULT" shall have the meaning set forth in Section
2(e) hereof.

          "REGISTRATION EXPENSES" shall mean any and all reasonable expenses
incident to performance of or compliance by the Company with this Agreement,
including without limitation: (i) all SEC, stock exchange or National
Association of Securities Dealers, Inc. registration and filing fees, (ii) all
fees and expenses incurred in connection with compliance with state securities
or blue sky laws (including reasonable fees and disbursements of counsel for any
underwriters or Holders in connection with blue sky qualification of any of the
Exchange Securities or Registrable Securities), (iii) all expenses of any
Persons in preparing or assisting in preparing, word processing, printing and
distributing any Registration Statement, any Prospectus, and any amendments or
supplements thereto, (iv) all rating agency fees, (v) all fees and disbursements
relating to the qualification of the Indenture under applicable securities laws,
(vi) the fees and disbursements of the Trustee and its counsel, (vii) the fees
and disbursements of counsel for the Company and, in the case of a Shelf
Registration Statement, the reasonable fees and disbursements of one counsel for
the Holders (which counsel shall be selected by the Majority Holders and which
counsel may also be counsel for the Initial Purchasers) and (viii) the fees and
disbursements of the independent public accountants of the Company, including
the expenses of any special audits or "cold comfort" letters required by or
incident to such performance and compliance, but excluding fees and expenses of
counsel to the underwriters (other than fees and expenses set forth in clause
(ii) above) or the Holders and underwriting discounts and commissions and
transfer taxes, if any, relating to the sale or disposition of Registrable
Securities by a Holder.

          "REGISTRATION STATEMENT" shall mean any registration statement of the
Company filed with the SEC that covers any of the Exchange Securities or the
Registrable Securities pursuant to the provisions of this Agreement and all
amendments and supplements to any such Registration Statement, including
post-effective

                                        3
<Page>

amendments, in each case including the Prospectus contained therein, all
exhibits thereto and all material incorporated by reference therein.

          "SEC" shall mean the Securities and Exchange Commission.

          "SHELF REGISTRATION" shall mean a registration effected pursuant to
Section 2(b) hereof.

          "SHELF REGISTRATION STATEMENT" shall mean a "shelf" registration
statement of the Company pursuant to the provisions of Section 2(b) of this
Agreement which covers all of the Registrable Securities (but no other
securities unless approved by the Holders whose Registrable Securities are
covered by such Shelf Registration Statement) on an appropriate form under Rule
415 under the 1933 Act, or any similar rule that may be adopted by the SEC, and
all amendments and supplements to such registration statement, including
post-effective amendments, in each case including the Prospectus contained
therein, all exhibits thereto and all material incorporated by reference
therein.

          "SPECIAL INTEREST" shall have the meaning set forth in Section 2(e)
hereof.

          "TIA" shall have the meaning set forth in Section 3 hereof.

          "TRUSTEE" shall mean the trustee with respect to the Securities under
the Indenture.

          "UNDERWRITERS" shall have the meaning set forth in Section 3 hereof.

          "UNDERWRITTEN REGISTRATION" or "Underwritten Offering" shall mean a
registration in which Registrable Securities are sold to an Underwriter for
reoffering to the public.

          2.      REGISTRATION UNDER THE 1933 ACT.

                  (a)  To the extent not prohibited by any applicable law or
applicable interpretation of the Staff of the SEC, the Company shall use its
reasonable best efforts to (i) file the Exchange Offer Registration Statement
with the SEC on or prior to the 120th day after the Closing Date; (ii) have the
Exchange Offer Registration Statement declared effective by the SEC no later
than the 180th day after the Closing Date; and (iii) consummate the Exchange
Offer no later than the 210th day after the Closing Date. The Company shall
commence the Exchange Offer by mailing the related exchange offer Prospectus and
accompanying documents to each Holder stating, in addition to such other
disclosures as are required by applicable law:

                       (i)    that the Exchange Offer is being made pursuant to
     this Registration Rights Agreement and that all Registrable Securities
     validly tendered will be accepted for exchange;

                                        4
<Page>

                       (ii)   the dates of acceptance for exchange (which shall
     be a period of at least 20 business days from the date such notice is
     mailed) (the "Exchange Dates");

                       (iii)  that any Registrable Security not tendered will
     remain outstanding and continue to accrue interest, but will not retain any
     rights under this Agreement;

                       (iv)   that Holders electing to have a Registrable
     Security exchanged pursuant to the Exchange Offer will be required to
     surrender such Registrable Security, together with the enclosed letters of
     transmittal, to the institution and at the address specified in the notice
     prior to the close of business on the last Exchange Date; and

                       (v)    that Holders will be entitled to withdraw their
     election, not later than the close of business on the last Exchange Date,
     by sending to the institution and at the address specified in the notice a
     facsimile transmission or letter setting forth the name of such Holder, the
     aggregate principal amount of Registrable Securities delivered for exchange
     and a statement that such Holder is withdrawing his election to have such
     Registrable Securities exchanged.

          As soon as practicable after the last Exchange Date, the Company
shall:

                       (i)    accept for exchange Registrable Securities or
     portions thereof tendered and not validly withdrawn pursuant to the
     Exchange Offer; and

                       (ii)   deliver, or cause to be delivered, to the Trustee
     for cancellation all Registrable Securities or portions thereof so accepted
     for exchange by the Company and issue, and cause the Trustee to promptly
     authenticate and mail to each Holder, an Exchange Security equal in
     aggregate principal amount to the aggregate principal amount of the
     Registrable Securities surrendered by such Holder.

The Company shall use its reasonable best efforts to complete the Exchange Offer
as provided above and shall comply with the applicable requirements of the 1933
Act, the 1934 Act and other applicable laws and regulations in connection with
the Exchange Offer. The Exchange Offer shall not be subject to any conditions,
other than that the Exchange Offer does not violate applicable law or any
applicable interpretation of the Staff of the SEC. The Company shall inform the
Initial Purchasers of the names and addresses of the Holders to whom the
Exchange Offer is made, and the Initial Purchasers shall have the right, subject
to applicable law, to contact such Holders and otherwise facilitate the tender
of Registrable Securities in the Exchange Offer.

                  (b)  In the event that (i) the Company determines that the
Exchange Offer Registration provided for in Section 2(a) above is not available
or may not be consummated as soon as practicable after the last Exchange Date
because it would violate applicable law or the applicable interpretations of the
Staff of the SEC, (ii) the

                                        5
<Page>

Exchange Offer is not for any other reason consummated within 210 days after the
Closing Date or (iii) the Exchange Offer has been completed and in the
reasonable opinion of counsel for the Initial Purchasers a Registration
Statement must be filed and a Prospectus must be delivered by the Initial
Purchasers in connection with any offering or sale of Registrable Securities,
the Company shall use its reasonable best efforts to cause to be filed as soon
as practicable, but no later than 30 days after such determination, date or
notice of such opinion of counsel is given to the Company, as the case may be, a
Shelf Registration Statement providing for the sale by the Holders of all of the
Registrable Securities and to have such Shelf Registration Statement declared
effective by the SEC no later than 90 days after such Shelf Registration
Statement is filed. In the event the Company is required to file a Shelf
Registration Statement solely as a result of the matters referred to in clause
(iii) of the preceding sentence, the Company shall use its reasonable best
efforts to file and have declared effective by the SEC both an Exchange Offer
Registration Statement pursuant to Section 2(a) with respect to all Registrable
Securities and a Shelf Registration Statement (which may be a combined
Registration Statement with the Exchange Offer Registration Statement) with
respect to offers and sales of Registrable Securities held by the Initial
Purchasers after completion of the Exchange Offer. The Company agrees to use its
reasonable best efforts to keep the Shelf Registration Statement continuously
effective until the expiration of the period referred to in Rule 144(k) under
the 1933 Act with respect to the Registrable Securities or such shorter period
that will terminate when all of the Registrable Securities covered by the Shelf
Registration Statement have been sold pursuant to the Shelf Registration
Statement. The Company further agrees to supplement or amend the Shelf
Registration Statement if required by the rules, regulations or instructions
applicable to the registration form used by the Company for such Shelf
Registration Statement or by the 1933 Act or by any other rules and regulations
thereunder for shelf registration or if reasonably requested by a Holder with
respect to information relating to such Holder, and to use its reasonable best
efforts to cause any such amendment to become effective and such Shelf
Registration Statement to become usable as soon as practicable thereafter. The
Company agrees to furnish to the Holders of Registrable Securities copies of any
such supplement or amendment promptly after its being used or filed with the
SEC.

                  (c)  The Company shall pay all Registration Expenses in
connection with the registration pursuant to Section 2(a) and Section 2(b). Each
Holder shall pay all underwriting discounts and commissions and transfer taxes,
if any, relating to the sale or disposition of such Holder's Registrable
Securities pursuant to a Shelf Registration Statement.

                  (d)  An Exchange Offer Registration Statement pursuant to
Section 2(a) hereof or a Shelf Registration Statement pursuant to Section 2(b)
hereof will not be deemed to have become effective unless it has been declared
effective by the SEC; PROVIDED, HOWEVER, that, if, after it has been declared
effective, the offering of Registrable Securities pursuant to a Shelf
Registration Statement is interfered with by any stop order, injunction or other
order or requirement of the SEC or any other governmental agency or court, such
Registration Statement will be deemed not to have become effective during the
period of such interference until the offering of Registrable Securities
pursuant to such Registration Statement may legally resume.

                                        6
<Page>

                  (e)  In the event that (i) the Company has not filed the
Exchange Offer Registration Statement or Shelf Registration Statement on or
before the date on which such registration statement is required to be filed
pursuant to Section 2(a) or 2(b), respectively, or (ii) such Exchange Offer
Registration Statement or Shelf Registration Statement has not become effective
or been declared effective by the Commission on or before the date on which such
registration statement is required to become or be declared effective pursuant
to Section 2(a) or 2(b), respectively, or (iii) the Exchange Offer has not been
completed within 210 days after Closing Date (if the Exchange Offer is then
required to be made) or (iv) any Exchange Offer Registration Statement or Shelf
Registration Statement required by Section 2(a) or 2(b) hereof is filed and
declared effective but shall thereafter either be withdrawn by the Company or
shall become interfered with by any stop order, injunction or other order or
requirement of the SEC or any other governmental agency or court (each such
event referred to in clauses (i) through (iv), a "Registration Default"), then,
as liquidated damages for such Registration Default, subject to the provisions
of Section 2(f) hereof, special interest ("Special Interest"), in addition to
the Base Interest, shall accrue on the Registrable Securities at a rate of 0.25%
per annum following the first Registration Default, and following the occurrence
of the second Registration Default, such Special Interest shall increase by an
additional 0.25% per annum, up to a maximum amount of 0.50% per annum. Such
Special Interest shall remain in effect until the Exchange Offer is completed or
the Shelf Registration Statement is declared effective.

                  (f)  Without limiting the remedies available to the Initial
Purchasers and the Holders, the Company acknowledges that any failure by the
Company to comply with its obligations under Section 2(a) and Section 2(b)
hereof may result in material irreparable injury to the Initial Purchasers or
the Holders for which there is no adequate remedy at law, that it will not be
possible to measure damages for such injuries precisely and that, in the event
of any such failure, the Initial Purchasers or any Holder may obtain such relief
as may be required to specifically enforce the Company's obligations under
Section 2(a) and Section 2(b) hereof.

          3.      REGISTRATION PROCEDURES.

          In connection with the obligations of the Company with respect to the
Registration Statements pursuant to Section 2(a) and Section 2(b) hereof, the
Company shall promptly:

                  (a)  prepare and file with the SEC a Registration Statement on
the appropriate form under the 1933 Act, which form (x) shall be selected by the
Company and (y) shall, in the case of a Shelf Registration, be available for the
sale of the Registrable Securities by the selling Holders thereof and (z) shall
comply as to form in all material respects with the requirements of the
applicable form and include all financial statements required by the SEC to be
filed therewith, and use its reasonable best efforts to cause such Registration
Statement to become effective and remain effective in accordance with Section 2
hereof;

                                        7
<Page>

                  (b)  prepare and file with the SEC such amendments and
post-effective amendments to each Registration Statement as may be necessary to
keep such Registration Statement effective for the applicable period and cause
each Prospectus to be supplemented by any required prospectus supplement and, as
so supplemented, to be filed pursuant to Rule 424 under the 1933 Act; to keep
each Prospectus current during the period described under Section 4(3) and Rule
174 under the 1933 Act that is applicable to transactions by brokers or dealers
with respect to the Registrable Securities or Exchange Securities;

                  (c)  in the case of a Shelf Registration, furnish to each
Holder of Registrable Securities, to counsel for the Initial Purchasers, to
counsel for the Holders and to each Underwriter of an Underwritten Offering of
Registrable Securities, if any, without charge, as many copies of each
Prospectus, including each preliminary Prospectus, and any amendment or
supplement thereto, including financial statements and schedules, and, if the
Holder so requests in writing, all exhibits thereto (including those, if any,
incorporated by reference) and such other documents as such Holder or
Underwriter may reasonably request, in order to facilitate the public sale or
other disposition of the Registrable Securities; and the Company consents to the
use of such Prospectus and any amendment or supplement thereto in accordance
with applicable law by each of the selling Holders of Registrable Securities and
any such Underwriters in connection with the offering and sale of the
Registrable Securities covered by and in the manner described in such Prospectus
or any amendment or supplement thereto in accordance with applicable law;

                  (d)  use its reasonable best efforts (i) to register or
qualify the Registrable Securities under all applicable state securities or
"blue sky" laws of such jurisdictions as any Holder of Registrable Securities
covered by a Registration Statement shall reasonably request in writing by the
time the applicable Registration Statement is declared effective by the SEC and
(ii) to cooperate with such Holders in connection with any filings required to
be made with the National Association of Securities Dealers, Inc. and do any and
all other acts and things which may be reasonably necessary or advisable to
enable such Holder to consummate the disposition in each such jurisdiction of
such Registrable Securities owned by such Holder; PROVIDED, HOWEVER, that the
Company shall not be required to (A) qualify as a foreign corporation or as a
dealer in securities in any jurisdiction where it would not otherwise be
required to qualify but for this Section 3(d), (B) file any general consent to
service of process or (C) subject itself to taxation in any such jurisdiction if
it is not so subject;

                  (e)  in the case of a Shelf Registration, notify each Holder
of Registrable Securities, counsel for the Holders and counsel for the Initial
Purchasers promptly and, if requested by any such Holder or counsel, confirm
such advice in writing, (i) when a Registration Statement has become effective
and when any post-effective amendment thereto has been filed and becomes
effective, (ii) of any request by the SEC or any state securities authority for
amendments and supplements to a Registration Statement and Prospectus or for
additional information after the Registration Statement has become effective,
(iii) of the issuance by the SEC or any state securities authority of any stop
order suspending the effectiveness of a Registration Statement or the initiation

                                        8
<Page>

of any proceedings for that purpose, (iv) if, between the effective date of a
Registration Statement and the closing of any sale of Registrable Securities
covered thereby, the representations and warranties of the Company contained in
any underwriting agreement, securities sales agreement or other similar
agreement, if any, relating to the offering cease to be true and correct in all
material respects or if the Company receives any notification with respect to
the suspension of the qualification of the Registrable Securities for sale in
any jurisdiction or the initiation of any proceeding for such purpose, (v) of
the happening of any event during the period a Shelf Registration Statement is
effective which makes any statement made in such Registration Statement or the
related Prospectus untrue in any material respect or which requires the making
of any changes in such Registration Statement or Prospectus in order to make the
statements therein not misleading and (vi) of any determination by the Company
that a post-effective amendment to a Registration Statement would be
appropriate;

                  (f)  make every reasonable effort to obtain the withdrawal of
any order suspending the effectiveness of a Registration Statement at the
earliest possible moment and provide immediate notice to each Holder of the
withdrawal of any such order;

                  (g)  in the case of a Shelf Registration, furnish to each
Holder of Registrable Securities, without charge, at least one conformed copy of
each Registration Statement and any post-effective amendment thereto (without
documents incorporated therein by reference or exhibits thereto, unless
requested);

                  (h)  in the case of a Shelf Registration, cooperate with the
selling Holders of Registrable Securities to facilitate the timely preparation
and delivery of certificates representing Registrable Securities to be sold and
not bearing any restrictive legends and enable such Registrable Securities to be
in such denominations (consistent with the provisions of the Indenture) and
registered in such names as the selling Holders may reasonably request at least
one business day prior to the closing of any sale of Registrable Securities;

                  (i)  in the case of a Shelf Registration, upon the occurrence
of any event contemplated by Section 3(e)(v) hereof, use its reasonable best
efforts to prepare and file with the SEC a supplement or post-effective
amendment to a Registration Statement or the related Prospectus or any document
incorporated therein by reference or file any other required document so that,
as thereafter delivered to the purchasers of the Registrable Securities, such
Prospectus will not contain any untrue statement of a material fact or omit to
state a material fact necessary to make the statements therein, in light of the
circumstances under which they were made, not misleading. The Company agrees to
notify the Holders to suspend use of the Prospectus as promptly as practicable
after the occurrence of such an event, and the Holders hereby agree to suspend
use of the Prospectus until the Company has amended or supplemented the
Prospectus to correct such misstatement or omission;

                  (j)  a reasonable time prior to the filing of any Registration
Statement, any Prospectus, any amendment to a Registration Statement or
amendment or

                                        9
<Page>

supplement to a Prospectus or any document which is to be incorporated by
reference into a Registration Statement or a Prospectus after initial filing of
a Registration Statement, provide copies of such document to the Initial
Purchasers and their counsel (and, in the case of a Shelf Registration
Statement, the Holders and their counsel) and make such of the representatives
of the Company as shall be reasonably requested by the Initial Purchasers or
their counsel (and, in the case of a Shelf Registration Statement, the Holders
or their counsel) available for discussion of such document, and shall not at
any time file or make any amendment to the Registration Statement, any
Prospectus or any amendment of or supplement to a Registration Statement or a
Prospectus or any document which is to be incorporated by reference into a
Registration Statement or a Prospectus, of which the Initial Purchasers and
their counsel (and, in the case of a Shelf Registration Statement, the Holders
and their counsel) shall not have previously been advised and furnished a copy
or to which the Initial Purchasers or their counsel (and, in the case of a Shelf
Registration Statement, the Holders or their counsel) shall object in writing,
except for any amendment or supplement or document (a copy of which has been
previously furnished to the Initial Purchasers and their counsel (and, in the
case of a Shelf Registration Statement, the Holders and their counsel)) which
counsel to the Company shall advise the Company in writing is required in order
to comply with applicable law;

                  (k)  obtain a CUSIP number for all Exchange Securities or
Registrable Securities, as the case may be, not later than the effective date of
a Registration Statement and provide the Trustee with certificates for the
Exchange Notes or Registrable Notes, as the case may be, in form eligible for
deposit with The Depository Trust Company;

                  (l)  cause the Indenture to be qualified under the Trust
Indenture Act of 1939, as amended (the "TIA"), in connection with the
registration of the Exchange Securities or Registrable Securities, as the case
may be, cooperate with the Trustee and the Holders to effect such changes to the
Indenture as may be required for the Indenture to be so qualified in accordance
with the terms of the TIA and execute, and use its reasonable best efforts to
cause the Trustee to execute, all documents as may be required to effect such
changes and all other forms and documents required to be filed with the SEC to
enable the Indenture to be so qualified in a timely manner;

                  (m)  in the case of a Shelf Registration, make available for
inspection by a representative of the Holders of the Registrable Securities, any
Underwriter participating in any disposition pursuant to such Shelf Registration
Statement, and attorneys and accountants designated by the Holders, at
reasonable times and in a reasonable manner, all financial and other records,
pertinent documents and properties of the Company, and cause the respective
officers, directors and employees of the Company to supply all information
reasonably requested by any such representative, Underwriter, attorney or
accountant in connection with a Shelf Registration Statement;

                  (n)  in the case of a Shelf Registration, use its reasonable
best efforts to cause all Registrable Securities to be listed on any securities
exchange or any automated quotation system on which similar securities issued by
the Company are then

                                       10
<Page>

listed if requested by the Majority Holders, to the extent such Registrable
Securities satisfy applicable listing requirements;

                  (o)  use its reasonable best efforts to cause the Exchange
Securities or Registrable Securities, as the case may be, to be rated by two
nationally recognized statistical rating organizations (as such term is defined
in Rule 436(g)(2) under the 1933 Act);

                  (p)  if reasonably requested by any Holder of Registrable
Securities covered by a Registration Statement, (i) promptly incorporate in a
Prospectus supplement or post-effective amendment such information with respect
to such Holder as such Holder reasonably requests to be included therein and
(ii) make all required filings of such Prospectus supplement or such
post-effective amendment as soon as the Company has received notification of the
matters to be incorporated in such filing; and

                  (q)  in the case of a Shelf Registration, enter into such
customary agreements and take all such other reasonable actions in connection
therewith (including those requested in writing by the Holders of a majority of
the Registrable Securities being sold) in order to expedite or facilitate the
disposition of such Registrable Securities including, but not limited to, an
Underwritten Offering and in such connection, (i) to the extent possible, make
such representations and warranties to the Holders and any Underwriters of such
Registrable Securities with respect to the business of the Company and its
subsidiaries, the Registration Statement, Prospectus and documents incorporated
by reference or deemed incorporated by reference, if any, in each case, in form,
substance and scope as are customarily made by issuers to underwriters in
underwritten offerings and confirm the same if and when requested in writing,
(ii) obtain opinions of counsel to the Company (which counsel and opinions, in
form, scope and substance, shall be reasonably satisfactory to the Holders and
such Underwriters and their respective counsel) addressed to each selling Holder
and Underwriter of Registrable Securities, covering the matters customarily
covered in opinions requested in underwritten offerings, (iii) obtain "cold
comfort" letters from the independent certified public accountants of the
Company (and, if necessary, any other certified public accountant of any
subsidiary of the Company, or of any business acquired by the Company for which
financial statements and financial data are or are required to be included in
the Registration Statement) addressed to each Underwriter of Registrable
Securities, such letters to be in customary form and covering matters of the
type customarily covered in "cold comfort" letters in connection with
underwritten offerings, and (iv) deliver such documents and certificates as may
be reasonably requested in writing by the Holders of a majority in principal
amount of the Registrable Securities being sold or the Underwriters, and which
are customarily delivered in underwritten offerings, to evidence the continued
validity of the representations and warranties of the Company made pursuant to
clause (i) above and to evidence compliance with any customary conditions
contained in an underwriting agreement.

          In the case of a Shelf Registration Statement, the Company may require
each Holder of Registrable Securities to furnish to the Company such information

                                       11
<Page>

regarding the Holder and the proposed distribution by such Holder of such
Registrable Securities as the Company may from time to time reasonably request
in writing.

          In the case of a Shelf Registration Statement, each Holder agrees
that, upon receipt of any notice from the Company of the happening of any event
of the kind described in Section 3(e)(v) hereof, such Holder will forthwith
discontinue disposition of Registrable Securities pursuant to a Registration
Statement until such Holder's receipt of the copies of the supplemented or
amended Prospectus contemplated by Section 3(i) hereof, and, if so directed by
the Company, such Holder will deliver to the Company (at its expense) all copies
in its possession, other than permanent file copies then in such Holder's
possession, of the Prospectus covering such Registrable Securities current at
the time of receipt of such notice. If the Company shall give any such notice to
suspend the disposition of Registrable Securities pursuant to a Registration
Statement, the Company shall extend the period during which the Registration
Statement shall be maintained effective pursuant to this Agreement by the number
of days during the period from and including the date of the giving of such
notice to and including the date when the Holders shall have received copies of
the supplemented or amended Prospectus necessary to resume such dispositions.
The Company may give any such notice only twice during any 365 day period and
any such suspensions may not exceed 30 days for each suspension and there may
not be more than two suspensions in effect during any 365 day period.

          The Holders of Registrable Securities covered by a Shelf Registration
Statement who desire to do so may sell such Registrable Securities in an
Underwritten Offering. In any such Underwritten Offering, the investment banker
or investment bankers and manager or managers (the "Underwriters") that will
administer the offering will be selected by the Majority Holders of the
Registrable Securities included in such offering.

          4.      PARTICIPATION OF BROKER-DEALERS IN EXCHANGE OFFER.

                  (a)  The Company understands that the Staff of the SEC has
taken the position that any broker-dealer that receives Exchange Securities for
its own account in the Exchange Offer in exchange for Securities that were
acquired by such broker-dealer as a result of market-making or other trading
activities (a "Participating Broker-Dealer"), may be deemed to be an
"underwriter" within the meaning of the 1933 Act in connection with any resale
of such Exchange Securities.

          The Company understands that it is the Staff's position that if the
Prospectus contained in the Exchange Offer Registration Statement includes a
plan of distribution containing a statement to the above effect and the means by
which Participating Broker-Dealers may resell the Exchange Securities, without
naming the Participating Broker-Dealers or specifying the amount of Exchange
Securities owned by them, such Prospectus may be delivered by Participating
Broker-Dealers to satisfy their prospectus delivery obligation under the 1933
Act in connection with resales of Exchange Securities for their own accounts, so
long as the Prospectus otherwise meets the requirements of the 1933 Act.

                                       12
<Page>

                  (b)  In light of the above, notwithstanding the other
provisions of this Agreement, the Company agrees that the provisions of this
Agreement as they relate to a Shelf Registration shall also apply to an Exchange
Offer Registration to the extent, and with such reasonable modifications thereto
as may be, reasonably requested by the Initial Purchasers or by one or more
Participating Broker-Dealers, in each case as provided in clause (ii) below, in
order to expedite or facilitate the disposition of any Exchange Securities by
Participating Broker-Dealers consistent with the positions of the Staff recited
in Section 4(a) above; provided that:

                       (i)    the Company shall not be required to amend or
     supplement the Prospectus contained in the Exchange Offer Registration
     Statement, as would otherwise be contemplated by Section 3(i), for a period
     exceeding 90 days after the last Exchange Date (as such period may be
     extended pursuant to the penultimate paragraph of Section 3 of this
     Agreement) and Participating Broker-Dealers shall not be authorized by the
     Company to deliver and shall not deliver such Prospectus after such period
     in connection with the resales contemplated by this Section 4; and

                       (ii)   the application of the Shelf Registration
     procedures set forth in Section 3 of this Agreement to an Exchange Offer
     Registration, to the extent not required by the positions of the Staff of
     the SEC or the 1933 Act and the rules and regulations thereunder, will be
     in conformity with the reasonable request to the Company by the Initial
     Purchasers or with the reasonable request in writing to the Company by one
     or more broker-dealers who certify to the Initial Purchasers and the
     Company in writing that they anticipate that they will be Participating
     Broker-Dealers; and provided further that, in connection with such
     application of the Shelf Registration procedures set forth in Section 3 to
     an Exchange Offer Registration, the Company shall be obligated (x) to deal
     only with one entity representing the Participating Broker-Dealers, which
     shall be Morgan Stanley & Co. Incorporated unless it elects not to act as
     such representative, (y) to pay the fees and expenses of only one counsel
     representing the Participating Broker-Dealers, which shall be counsel to
     the Initial Purchasers unless such counsel elects not to so act and (z) to
     cause to be delivered only one, if any, "cold comfort" letter with respect
     to the Prospectus in the form existing on the last Exchange Date and with
     respect to each subsequent amendment or supplement, if any, effected during
     the period specified in clause (i) above.

                  (c)  The Initial Purchasers shall have no liability to the
     Company or any Holder with respect to any request that it may make pursuant
     to Section 4(b) above.

          5.      INDEMNIFICATION AND CONTRIBUTION.

                  (a)  The Company agrees to indemnify and hold harmless each
Initial Purchaser, each Holder, each Person, if any, who controls any Initial
Purchaser or any Holder within the meaning of either Section 15 of the 1933 Act
or Section 20 of the 1934 Act, and each affiliate of any Initial Purchaser or
any Holder within the meaning of

                                       13
<Page>

Rule 405 under the Securities Act, from and against all losses, claims, damages
and liabilities (including, without limitation, any legal or other expenses
reasonably incurred in connection with defending or investigating any such
action or claim) caused by any untrue statement or alleged untrue statement of a
material fact contained in any Registration Statement (or any amendment thereto)
pursuant to which Exchange Securities or Registrable Securities were registered
under the 1933 Act, including all documents incorporated therein by reference,
or caused by any omission or alleged omission to state therein a material fact
required to be stated therein or necessary to make the statements therein not
misleading, or caused by any untrue statement or alleged untrue statement of a
material fact contained in any Prospectus (as amended or supplemented if the
Company shall have furnished any amendments or supplements thereto), or caused
by any omission or alleged omission to state therein a material fact necessary
to make the statements therein in light of the circumstances under which they
were made not misleading, except insofar as such losses, claims, damages or
liabilities are caused by (i) any such untrue statement or omission or alleged
untrue statement or omission based upon information relating to any Initial
Purchasers or any Holder furnished to the Company in writing by Morgan Stanley &
Co. Incorporated or any selling Holder expressly for use therein or (ii) the
failure by such Initial Purchaser or such Holder to deliver a supplement or
amendment to any Prospectus which would have corrected such untrue statement or
omission or alleged untrue statement or omission.

                  (b)  Each Holder agrees, severally and not jointly, to
indemnify and hold harmless the Company, the Initial Purchasers and the other
selling Holders, and each of their respective directors, officers who sign the
Registration Statement and each Person, if any, who controls the Company, any
Initial Purchaser and any other selling Holder within the meaning of either
Section 15 of the 1933 Act or Section 20 of the 1934 Act to the same extent as
the foregoing indemnity from the Company to the Initial Purchasers and the
Holders, but only with reference to information relating to such Holder
furnished to the Company in writing by such Holder expressly for use in any
Registration Statement (or any amendment thereto) or any Prospectus (or any
amendment or supplement thereto).

                  (c)  In case any proceeding (including any governmental
investigation) shall be instituted involving any Person in respect of which
indemnity may be sought pursuant to either paragraph (a) or paragraph (b) above,
such Person (the "indemnified party") shall promptly notify the Person against
whom such indemnity may be sought (the "indemnifying party") in writing and the
indemnifying party, upon request of the indemnified party, shall retain counsel
reasonably satisfactory to the indemnified party to represent the indemnified
party and any others the indemnifying party may designate in such proceeding and
shall pay the fees and disbursements of such counsel related to such proceeding.
In any such proceeding, any indemnified party shall have the right to retain its
own counsel, but the fees and expenses of such counsel shall be at the expense
of such indemnified party unless (i) the indemnifying party and the indemnified
party shall have mutually agreed to the retention of such counsel or (ii) the
named parties to any such proceeding (including any impleaded parties) include
both the indemnifying party and the indemnified party and representation of both
parties by the same counsel would be inappropriate due to actual or potential
differing interests between them. It is

                                       14
<Page>

understood that the indemnifying party shall not, in connection with any
proceeding or related proceedings in the same jurisdiction, be liable for (a)
the fees and expenses of more than one separate firm (in addition to any local
counsel) for the Initial Purchasers and all Persons, if any, who control any
Initial Purchaser within the meaning of either Section 15 of the 1933 Act or
Section 20 of the 1934 Act, (b) the fees and expenses of more than one separate
firm (in addition to any local counsel) for the Company, its directors, its
officers who sign the Registration Statement and each Person, if any, who
controls the Company within the meaning of either such Section and (c) the fees
and expenses of more than one separate firm (in addition to any local counsel)
for all Holders and all Persons, if any, who control any Holders within the
meaning of either such Section, and that all such fees and expenses shall be
reimbursed as they are incurred. In such case involving the Initial Purchasers
and Persons who control the Initial Purchasers, such firm shall be designated in
writing by Morgan Stanley & Co. Incorporated. In such case involving the Holders
and such Persons who control Holders, such firm shall be designated in writing
by the Majority Holders. In all other cases, such firm shall be designated by
the Company. The indemnifying party shall not be liable for any settlement of
any proceeding effected without its written consent but, if settled with such
consent or if there be a final judgment for the plaintiff, the indemnifying
party agrees to indemnify the indemnified party from and against any loss or
liability by reason of such settlement or judgment. Notwithstanding the
foregoing sentence, if at any time an indemnified party shall have requested an
indemnifying party to reimburse the indemnified party for fees and expenses of
counsel as contemplated by the second and third sentences of this paragraph, the
indemnifying party agrees that it shall be liable for any settlement of any
proceeding effected without its written consent if (i) such settlement is
entered into more than 60 days after receipt by such indemnifying party of the
aforesaid request and (ii) such indemnifying party shall not have reimbursed the
indemnified party for such fees and expenses of counsel in accordance with such
request prior to the date of such settlement. No indemnifying party shall,
without the prior written consent of the indemnified party, effect any
settlement of any pending or threatened proceeding in respect of which such
indemnified party is or could have been a party and indemnity could have been
sought hereunder by such indemnified party, unless such settlement includes an
unconditional release of such indemnified party from all liability on claims
that are the subject matter of such proceeding.

                  (d)  If the indemnification provided for in paragraph (a) or
paragraph (b) of this Section 5 is unavailable to an indemnified party or
insufficient in respect of any losses, claims, damages or liabilities, then each
indemnifying party under such paragraph, in lieu of indemnifying such
indemnified party thereunder, shall contribute to the amount paid or payable by
such indemnified party as a result of such losses, claims, damages or
liabilities in such proportion as is appropriate to reflect the relative fault
of the indemnifying party or parties on the one hand and of the indemnified
party or parties on the other hand in connection with the statements or
omissions that resulted in such losses, claims, damages or liabilities, as well
as any other relevant equitable considerations. The relative fault of the
Company and the Holders shall be determined by reference to, among other things,
whether the untrue or alleged untrue statement of a material fact or the
omission or alleged omission to state a material fact relates to information
supplied by the Company or by the Holders and the parties' relative

                                       15
<Page>

intent, knowledge, access to information and opportunity to correct or prevent
such statement or omission. The Holders' respective obligations to contribute
pursuant to this Section 5(d) are several in proportion to the respective
principal amount of Registrable Securities of such Holder that were registered
pursuant to a Registration Statement.

                  (e)  The Company and each Holder agree that it would not be
just or equitable if contribution pursuant to this Section 5 were determined by
PRO RATA allocation or by any other method of allocation that does not take
account of the equitable considerations referred to in paragraph (d) above. The
amount paid or payable by an indemnified party as a result of the losses,
claims, damages and liabilities referred to in paragraph (d) above shall be
deemed to include, subject to the limitations set forth above, any legal or
other expenses reasonably incurred by such indemnified party in connection with
investigating or defending any such action or claim. Notwithstanding the
provisions of this Section 5, no Holder shall be required to indemnify or
contribute any amount in excess of the amount by which the total price at which
Registrable Securities were sold by such Holder exceeds the amount of any
damages that such Holder has otherwise been required to pay by reason of such
untrue or alleged untrue statement or omission or alleged omission. No Person
guilty of fraudulent misrepresentation (within the meaning of Section 11(f) of
the 1933 Act) shall be entitled to contribution from any Person who was not
guilty of such fraudulent misrepresentation. The remedies provided for in this
Section 5 are not exclusive and shall not limit any rights or remedies which may
otherwise be available to any indemnified party at law or in equity.

          The indemnity and contribution provisions contained in this Section 5
shall remain operative and in full force and effect regardless of (i) any
termination of this Agreement, (ii) any investigation made by or on behalf of
the Initial Purchasers, any Holder or any Person controlling any Initial
Purchaser or any Holder, or by or on behalf of the Company, its officers or
directors or any Person controlling the Company, (iii) acceptance of any of the
Exchange Securities and (iv) any sale of Registrable Securities pursuant to a
Shelf Registration Statement.

          6.      MISCELLANEOUS.

                  (a)  NO INCONSISTENT AGREEMENTS. The Company has not entered
into, and on or after the date of this Agreement will not enter into, any
agreement which is inconsistent with the rights granted to the Holders of
Registrable Securities in this Agreement or otherwise conflicts with the
provisions hereof. The rights granted to the Holders hereunder do not in any way
conflict with and are not inconsistent with the rights granted to the holders of
the Company's other issued and outstanding securities under any such agreements.

                  (b)  AMENDMENTS AND WAIVERS. The provisions of this Agreement,
including the provisions of this sentence, may not be amended, modified or
supplemented, and waivers or consents to departures from the provisions hereof
may not be given unless the Company has obtained the written consent of Holders
of at least a majority in aggregate principal amount of the outstanding
Registrable Securities affected by such amendment, modification, supplement,
waiver or consent; provided, however,

                                       16
<Page>

that no amendment, modification, supplement, waiver or consent to any departure
from the provisions of Section 5 hereof or which would have the effect of
reducing the rate or extending the time of payment of interest on any
Registrable Security shall be effective as against any Holder of Registrable
Securities unless consented to in writing by such Holder.

                  (c)  NOTICES. All notices and other communications provided
for or permitted hereunder shall be made in writing by hand-delivery, registered
first-class mail, facsimile, or any courier guaranteeing overnight delivery (i)
if to a Holder, at the most current address given by such Holder to the Company
by means of a notice given in accordance with the provisions of this Section
6(c), which address initially is, with respect to the Initial Purchasers, the
address set forth in the Purchase Agreement; and (ii) if to the Company,
initially at the Company's address set forth in the Purchase Agreement and
thereafter at such other address, notice of which is given in accordance with
the provisions of this Section 6(c).

          All such notices and communications shall be deemed to have been duly
given: at the time delivered by hand, if personally delivered; five business
days after being deposited in the mail, postage prepaid, if mailed; when receipt
is acknowledged, if sent by facsimile; and on the next business day if timely
delivered to an air courier guaranteeing overnight delivery.

          Copies of all such notices, demands, or other communications shall be
concurrently delivered by the Person giving the same to the Trustee, at the
address specified in the Indenture.

                  (d)  SUCCESSORS AND ASSIGNS. This Agreement shall inure to the
benefit of and be binding upon the successors, assigns and transferees of each
of the parties, including, without limitation and without the need for an
express assignment, subsequent Holders; provided that nothing herein shall be
deemed to permit any assignment, transfer or other disposition of Registrable
Securities in violation of the terms of the Purchase Agreement. If any
transferee of any Holder shall acquire Registrable Securities, in any manner,
whether by operation of law or otherwise, such Registrable Securities shall be
held subject to all of the terms of this Agreement, and by taking and holding
such Registrable Securities such Person shall be conclusively deemed to have
agreed to be bound by and to perform all of the terms and provisions of this
Agreement and such Person shall be entitled to receive the benefits hereof. The
Initial Purchasers (in their capacity as Initial Purchasers) shall have no
liability or obligation to the Company with respect to any failure by a Holder
to comply with, or any breach by any Holder of, any of the obligations of such
Holder under this Agreement.

                  (e)  PURCHASES AND SALES OF SECURITIES. The Company shall not,
and shall use its reasonable best efforts to cause its affiliates (as defined in
Rule 405 under the 1933 Act) not to, purchase and then resell or otherwise
transfer any Securities.

                  (f)  THIRD PARTY BENEFICIARY. The Holders shall be third party
beneficiaries to the agreements made hereunder between the Company, on the one
hand,

                                       17
<Page>

and the Initial Purchasers, on the other hand, and shall have the right to
enforce such agreements directly to the extent it deems such enforcement
necessary or advisable to protect its rights or the rights of Holders hereunder.

                  (g)  COUNTERPARTS. This Agreement may be executed in any
number of counterparts and by the parties hereto in separate counterparts, each
of which when so executed shall be deemed to be an original and all of which
taken together shall constitute one and the same agreement.

                  (h)  HEADINGS. The headings in this Agreement are for
convenience of reference only and shall not limit or otherwise affect the
meaning hereof.

                  (i)  GOVERNING LAW. This Agreement shall be governed by the
laws of the State of New York.

                  (j)  SEVERABILITY. In the event that any one or more of the
provisions contained herein, or the application thereof in any circumstance, is
held invalid, illegal or unenforceable, the validity, legality and
enforceability of any such provision in every other respect and of the remaining
provisions contained herein shall not be affected or impaired thereby.

                                       18
<Page>

          IN WITNESS WHEREOF, the parties have executed this Agreement as of the
date first written above.

                                        HOSPIRA, INC.

                                        By /s/ Terrence C. Kearney
                                           ------------------------------
                                           Name: Terrence C. Kearney
                                           Title: Senior Vice President, Finance
                                                  and Chief Financial Officer

Confirmed and accepted as of
the date first above written:

As representatives of the Initial Purchasers

MORGAN STANLEY & CO. INCORPORATED
ABN AMRO INCORPORATED
CITIGROUP GLOBAL MARKETS INC.

By:MORGAN STANLEY & CO. INCORPORATED

By /s/ Harold J. Hendershot III
   -----------------------------------
   Name: Harold J. Hendershot III
   Title: Executive Director

By: ABN AMRO INCORPORATED

By /s/ Paul Hatton
   -----------------------------------
   Name:  Paul Hatton
   Title: Director

By: CITIGROUP GLOBAL MARKETS INC.

By /s/ Darin Bay
   --------------------------
   Name: Darin Bay
   Title:  Vice President

                                       19
<Page>

                                   SCHEDULE I

<Table>
<Caption>
                                          PRINCIPAL AMOUNT   PRINCIPAL AMOUNT
                                          OF 4.95% NOTES TO  OF 5.90% NOTES TO
        INITIAL PURCHASER                   BE PURCHASED       BE PURCHASED
<S>                                       <C>                <C>
Morgan Stanley & Co. Incorporated........ $    80,000,000    $   106,667,000
ABN AMRO Incorporated....................      80,000,000        106,667,000
Citigroup Global Markets Inc.............      80,000,000        106,667,000
Banc of America Securities LLC...........      12,000,000         16,000,000
Banc One Capital Markets, Inc............      12,000,000         16,000,000
BNP Paribas Securities Corp. ............       6,000,000          8,000,000
Commerzbank Capital Markets Corp. .......       6,000,000          8,000,000
Harris Nesbitt Corp. ....................       6,000,000          8,000,000
Tokyo-Mitsubishi International plc.......       6,000,000          8,000,000
SunTrust Capital Markets, Inc. ..........       6,000,000          8,000,000
Wachovia Capital Markets, LLC............       6,000,000          8,000,000
         Total:.......................... $   300,000,000    $   400,000,000
</Table>

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