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                                                                   EXHIBIT 10.28

                           ALTUS PHARMACEUTICALS INC.
                          DIRECTOR COMPENSATION POLICY

      The Compensation Committee of the Board of Directors of Altus
Pharmaceuticals Inc. (the "Company") has approved the following policy which
establishes compensation to be paid to non-employee directors of the Company,
effective as of the closing of the Company's initial public offering (the
"Effective Time"), to provide an inducement to obtain and retain the services of
qualified persons to serve as members of the Company's Board of Directors. All
stock option amounts set forth herein shall be subject to automatic adjustment
in the event of any stock split or other recapitalization affecting the
Company's common stock following the Effective Time.

APPLICABLE PERSONS

      This Policy shall apply to each director of the Company who is not an
employee of, or compensated consultant to, the Company or any Affiliate, unless
such compensation is received solely for services provided as a member of the
Scientific Advisory Board (each, an "Outside Director"). Affiliate shall mean a
corporation which is a direct or indirect parent or subsidiary of the Company,
as determined pursuant to Section 424 of the Internal Revenue Code of 1986, as
amended.

STOCK OPTION GRANTS

      Annual Grants

      Each Outside Director shall annually be granted a non-qualified stock
option to purchase 8,722 shares of the Company's common stock under the
Company's Amended and Restated 2002 Employee, Director and Consultant Stock Plan
(the "Stock Plan") at the annual meeting of the Board of Directors following the
Company's annual meeting of stockholders; provided that if there has been no
annual meeting of stockholders held by the first day of the third fiscal quarter
of the year in which the Effective Time occurs, each Outside Director will still
receive any annual grants of non-qualified stock options provided for under this
policy on the first day of the third fiscal quarter of the year; and provided
further, that if an annual meeting of stockholders is subsequently held during
the year in which the Effective Time occurs, no additional annual grant shall be
made. Unless otherwise specified by the Board or the Compensation Committee at
the time of grant, all options granted under this policy shall (i) vest
quarterly over four years, subject to the Outside Director's continued service
on the Board; provided that such options shall become exercisable in full
immediately prior to a change in control of the Company, (ii) have an exercise
price equal to the fair market value of the Company's common stock as determined
in the Stock Plan, and (iii) contain such other terms and conditions as the
Board or the Compensation Committee shall determine; and provided, further,
however, that any options granted under this policy on or before the first day
of the third fiscal quarter of 2006 to any Outside Director who was serving as
an Outside Director as of the Effective Time shall vest quarterly over four
years, and such vesting shall commence as of January 1, 2006.

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      Initial Grant For Newly Appointed or Elected Directors

      Each new Outside Director on the date of his or her initial appointment or
election to the Board of Directors shall be granted a non-qualified stock option
to purchase 17,444 shares of the Company's common stock under the Stock Plan.

ANNUAL CASH FEE

      Each Outside Director shall be compensated on an annual basis for
providing services to the Company. Each Outside Director shall receive an annual
fee of $20,000.

      Cash Payments

      Cash payments to be paid to an Outside Director shall be paid quarterly in
arrears as of the last day of each calendar quarter. If an Outside Director
dies, resigns or is removed during any quarter, he or she shall be entitled to a
cash payment on a pro rata basis through his or her last day of service.

      Initial Fee Upon Institution of Policy

      On the last day of the first fiscal quarter following the Effective Time,
each Outside Director then serving shall be paid his or her quarterly cash
compensation prorated for the period from January 1, 2006 through such date.
Thereafter, quarterly cash payments shall be made in accordance with this
policy.

      Initial Fee For Newly Appointed or Elected Directors

      On the last day of the first fiscal quarter following an Outside
Director's first election or appointment to the Board of Directors after the
Effective Time, such Outside Director shall receive his or her quarterly cash
compensation prorated in accordance with the terms of this Policy from the
beginning of the calendar quarter in which he or she was initially appointed or
elected and payable as set forth above.

                                       2exv10w01

 

Exhibit 10.01

THIRD AMENDMENT TO EMPLOYMENT AGREEMENT

     This THIRD AMENDMENT (this “Amendment”) is made as of the 10th day of January, 2006
between Fisher Scientific International Inc., a Delaware corporation having its primary place of
business at Liberty Lane, Hampton, New Hampshire 03842 (the “Company”) and David T. Della Penta,
residing at
(                  )
(the “Executive”).

     The Company and the Executive entered into an employment agreement as of the 31st day of
March, 1998, which was amended as of December 31st, 2003, and again as of August 2, 2005
(as amended, the “Employment Agreement”). The Employment Agreement originally provided, in
Section 1 thereof, for an Employment Period of three years (commencing as of April 20, 1998), which
Employment Period was subject to automatic extensions of one year, which extensions occurred on
each anniversary of April 20, 1998 (absent notice of non-renewal from either party). On January
10, 2006, the Company’s Compensation Committee accepted the Executive’s notification of retirement,
effective December 30, 2006. Accordingly, the Employment Agreement is hereby amended, as set forth
below:

     1. Section 1 of the Employment Agreement is hereby amended and restated in its entirety to
read:

     EMPLOYMENT PERIOD. Subject to the terms and conditions of this Agreement, the Company hereby
agrees to employ the Executive, and the Executive hereby agrees to be employed by the Company for
the period commencing on April 20, 1998 (the “Effective Date”) and ending on the third anniversary
of such date, together with any extension thereof (the “Employment Period”). On each anniversary of
the date hereof, unless either party hereto shall have given the other party thirty (30) days’
advance notice to the contrary, the Employment Period shall be extended by an additional year, so
that on each anniversary of the date hereof the Employment Period shall always consist of three
years. Notwithstanding the foregoing, the Employment Period shall terminate effective as of
December 30, 2006, on account of the Executive’s retirement, which retirement shall be treated for
purposes of this Agreement as a resignation by the Executive without Good Reason.

     2. Except as expressly provided in this Amendment, the terms and provisions of the Employment
Agreement shall remain in full force and effect.

     The Executive has hereunto set the Executive’s hand and, pursuant to the authorization from
its Board of Directors, the Company has caused this Agreement to be executed in its name on its
behalf, all as of the day and year first above written.

	 	 	 	 	 
	 	 	FISHER SCIENTIFIC INTERNATIONAL INC.
	/s/
David T. Della Penta
	 	 	 	 
	 
	 	 	 	 
	DAVID T. DELLA PENTA
	 	By:	 	/s/ Kevin P. Clark
	 
	 	 	 	 
	 
	 	 	 	KEVIN P. CLARK

1exv10w02

 

Exhibit 10.02

SECOND AMENDMENT TO EMPLOYMENT AGREEMENT

     This SECOND AMENDMENT (this “Amendment”) is made as of the 10th day of January,
2006 between Fisher Scientific International Inc., a Delaware corporation having its primary place
of business at Liberty Lane, Hampton, New Hampshire 03842 (the “Company”) and Paul M. Meister (the
“Executive”).

     The Company and the Executive entered into an Amended and Restated Employment Agreement as of
the 31st day of December, 2003, as amended as of August 2, 2005 (the “Employment Agreement”). The
Company and the Executive have agreed to amend the provisions of the Employment Agreement dealing
with the definition of Good Reason. Accordingly, the Employment Agreement is hereby amended, as
set forth below:

     1. Section 4(c) of the Employment Agreement is hereby amended and restated in its entirety to
read:

     (c) Good Reason. The Executive’s employment may be terminated by the
Executive for Good Reason at any time within 90 days after the Executive first
has actual knowledge of the occurrence of such Good Reason. For purposes of this
Agreement, “Good Reason” shall mean:

     (i) the assignment to the Executive of any duties inconsistent in any respect with the
Executive’s position (including status and offices), authority, duties or responsibilities as
contemplated by Section 2 of this Agreement, or any other action by the Company which results in a
diminution in such position, authority, duties or responsibilities;

     (ii) any adverse change to the Executive’s title or reporting lines or relationships,
including a change in the individual who is currently serving as the
Company’s Chief Executive
Officer;

     (iii) any failure by the Company to comply with any of the provisions of Section 3 of this
Agreement;

     (iv) the Company’s (1) requiring the Executive to be based at any office or location other
than as provided in Section 2 hereof or the Company’s requiring the Executive to travel on Company
business to a substantially greater extent than required immediately prior to the Effective Date or
(2) relocating its principal executive offices to a location more than 25 miles from their location
on January 10, 2006;

     (v) any purported termination by the Company of the Executive’s employment otherwise than as
expressly permitted by this Agreement;

     (vi) the occurrence of a Change in Control of the Company, as defined in the Company’s 2005
Equity and Incentive Plan, as in effect on January 10, 2006;

     (vii) any delivery by the Company of a Notice of Non-Extension; or

1

 

     (viii) any failure by the Company to comply with and satisfy Section 9 of this Agreement.

For purposes of this Section 4(c), any good faith determination of “Good Reason” made by the
Executive shall be conclusive.

     2. Except as expressly provided in this Amendment, the terms and provisions of the Employment
Agreement shall remain in full force and effect.

     The Executive has hereunto set the Executive’s hand and, pursuant to the authorization from
its Board of Directors, the Company has caused this Agreement to be executed in its name on its
behalf, all as of the day and year first above written.

	 	 	 	 	 
	 	 	FISHER SCIENTIFIC INTERNATIONAL INC.
	 	 	 	 	 
	/s/ Paul M. Meister 
	 	By:	 	/s/ Kevin P. Clark
	 

	 	 	 	 
	PAUL M. MEISTER
	 	 	 	KEVIN P. CLARK

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