Document:

<PAGE>

                                                                    Exhibit 10.2

                                 April 29, 2001

Aurora Biosciences Corporation
11010 Torreyana Road
San Diego, CA 92121

Re:      Stockholder Agreement

Gentlemen:

         The undersigned (the "Stockholder") owns of record and beneficially the
number of shares (the "Shares") of common stock of Vertex Pharmaceuticals
Incorporated, a Massachusetts corporation ("Acquiror"), as set forth below. It
is contemplated that Acquiror, Aurora Biosciences Corporation, a Delaware
corporation ("Target") and Ahab Acquisition Sub, Inc., a Delaware corporation
and a newly organized wholly owned subsidiary of Acquiror ("Merger Sub"), will
enter into an Agreement and Plan of Merger (the "Agreement") with respect to the
merger (the "Merger") of Merger Sub with and into Target. Pursuant to the
Merger, each outstanding share of Target common stock will be converted into the
right to receive shares of Acquiror's common stock, all as more specifically
provided in the Agreement. The Stockholder wishes to facilitate the proposed
Merger and acknowledges that the proposed Merger will benefit the Stockholder.

         In consideration of the foregoing, and for other good and valuable
consideration, the receipt and sufficiency of which are hereby acknowledged, and
intending to be legally bound hereby, the Stockholder agrees as follows:

         1.       STANDSTILL. The Stockholder agrees that, until the earlier of
the Effective Time (as defined in the Agreement), or the termination of the
Agreement in accordance with its terms, Stockholder shall not offer, sell,
contract to sell, transfer or otherwise dispose of, or grant any option to
purchase, or convert, any of the Shares. The restrictions on transfer contained
in this Paragraph 1 shall not apply to transfers by the Stockholder (i) to the
Stockholder's spouse, children or other member of the Stockholder's immediate
family, or a trust for the benefit of such persons, (ii) to the trustee or
trustees of a trust revocable solely by the Stockholder, (iii) to the
Stockholder's guardian or conservator, or (iv) in the event of the Stockholder's
death, to the Stockholder's executor(s), administrator(s) or trustee(s) under
the Stockholder's will (collectively, the "Permitted Transferees"); provided,
however, that in any such event the Shares so transferred in the hands of each
such Permitted Transferee shall remain subject to the provisions of this
Agreement, and each such Permitted Transferee shall so acknowledge in writing as
a condition precedent to the effectiveness of such transfer. As security for the
Stockholder's obligations under this paragraph, the Stockholder hereby assigns
to and grants to Target a lien upon and a security interest in the Shares.

         2.       PROXY.

         (a)      As further security for the Stockholder's obligations under
paragraph 1, the Stockholder hereby (i) revokes any previous proxies relating to
the Shares and (ii) irrevocably appoints, Stuart Collinson, Chairman, Chief
Executive Officer and President of the Target, Tom Klopack, Senior Vice
President and Chief Operating Officer of the Target, and Chris Krueger, General
Counsel and Vice President, Strategic Alliances of the Target, and each of them,
attorneys and proxies, with power of substitution in each of them, of the
Stockholder to (w) attend any and all meetings (and at all adjournments,
continuations or postponements, thereof) (the "Meeting(s)") of the stockholders
of Acquiror at which the Merger is presented for approval of such stockholders,
(x) represent the Stockholder at any such Meeting(s), (y) vote the Shares in
favor of the Merger on the terms set forth in the Agreement as executed (with
such changes as are not material to the rights of the Stockholder in the Merger)
at any such Meeting(s) and to vote the Shares in favor of other matters in
connection therewith, and (z) otherwise act for the Stockholder in the same
manner and with the same effect as if the Stockholder were personally present at
such Meeting(s) and voting the Shares or personally acting on any matters in
connection with the Merger submitted to the stockholders of Acquiror for
approval or consent (including executing waivers and consents in connection with
the Merger). Stuart Collinson, Tom Klopack and Chris Krueger hereby agree that
they shall vote the Shares at any such Meeting(s) in favor of the Merger on the
terms set forth in the Agreement as executed (with such changes as are not
material to the rights of the Stockholder in the Merger), and with respect to
other matters in connection therewith, provided, however, that the Target's
conditions to closing set forth in the Agreement have been satisfied.

<PAGE>

         (b)      The Stockholder authorizes such proxies to substitute any
other person or persons to act hereunder, to revoke any such substitution and to
file this proxy and any such substitution or revocation with the Secretary of
Acquiror.

         (c)      THIS PROXY IS IRREVOCABLE AND COUPLED WITH AN INTEREST AND
SHALL TERMINATE ON THE EARLIER OF THE EFFECTIVE TIME OR THE TERMINATION OF THE
AGREEMENT PURSUANT TO THE TERMS THEREOF.

         3.       REPRESENTATIONS AND WARRANTIES BY STOCKHOLDER. The Stockholder
represents and warrants to Target that:

         (a)      the Stockholder has all necessary power and authority to
execute this letter agreement including the proxy appointment contained herein;

         (b)      this letter agreement and proxy has been duly executed and
delivered by the Stockholder and constitutes a valid and binding agreement of
the Stockholder, enforceable in accordance with its terms; and

         (c)      neither the execution nor delivery of this letter agreement
and proxy by the Stockholder will (i) require the consent, waiver, approval,
license or authorization, or any filing with, any person or public authority,
(ii) with or without the giving of notice or the lapse of time, or both,
conflict with or constitute a violation of, or default under, or give rise to
any right of acceleration under any indenture, contract, commitment, agreement,
arrangement or other instrument of any kind to which the Stockholder is a party
or by which the Stockholder is bound, or (iii) violate any applicable law, rule,
regulation, judgment, order or degree of any governmental instrumentality or
court having jurisdiction over the Stockholder.

         4.       MISCELLANEOUS. The Stockholder will not take any action that
would prevent or frustrate Target's rights under the Agreement.

           [The remainder of this page is intentionally left blank.]

<PAGE>

         IN WITNESS WHEREOF, the Stockholder has executed this agreement and
proxy as of the date and year first above written.

                                    STOCKHOLDER:

                                    (Individual)

                                    /s/ Joshua Boger
                                    --------------------------------------------
                                    Print Name: Joshua Boger
                                                --------------------------------

                                    (Entity)

                                    --------------------------------------------
                                    By:
                                       -----------------------------------------
                                       Name:
                                            ------------------------------------
                                       Title:
                                             -----------------------------------

                                    Number of Shares of
                                    Common Stock  1,063,751  1,646,198 (OPTIONS)
                                                --------------------------------

The undersigned hereby acknowledges their obligation to vote the Shares at any
Meeting(s) in favor of the Merger as provided in Section 2(a) hereof.

/s/ Stuart Collinson
------------------------------
Stuart Collinson

/s/ Tom Klopack
------------------------------
Tom Klopack

/s/ C. W. Krueger
------------------------------
Chris Krueger

<PAGE>

                     Schedule of Other Stockholders Signing
                       This Form of Stockholder Agreement

Bruce I. Sachs
Charles A. Sanders
Donald R. Conklin
John Alam
Lynne Brum
Iain Buchanan
Roger W. Brimblecombe
Elaine Ullian
Vicki Sato
Barry M. BloomPrepared by MERRILL CORPORATION

QuickLinks
 -- Click here to rapidly navigate through this document

Exhibit 4.1  

	NUMBER	LIBERTY LIVEWIRE CORPORATION	SHARES
	LLW	INCORPORATED UNDER THE LAWS OF THE STATE OF DELAWARE

CLASS A COMMON STOCK	 
	 	 	CUSIP 530709 10 4
 SEE REVERSE FOR CERTAIN DEFINITIONS
	THIS CERTIFIES THAT	 	 

is the owner of 

    FULLY-PAID AND NON-ASSESSABLE SHARES OF THE PAR VALUE OF $0.1 EACH OF THE CLASS A COMMON STOCK OF LIBERTY LIVEWIRE CORPORATION,
transferable in person or by duly authorized attorney upon surrender of this Certificate properly endorsed. This Certificate and the shares represented hereby are subject to all of the terms and
conditions contained in the Certificate of Incorporation of the Corporation and all amendments thereto. This Certificate is not valid unless countersigned by the Transfer Agent and registered by the
Registrar. 

IN
WITNESS WHEREOF the Corporation has caused the facsimile signatures of its duly authorized officers to be hereunto affixed. 

Date: 

	/s/	 	/s/
	
	 	

	Vice President/Treasurer	 	Chief Executive Officer

Countersigned and Registered:  

 CONTINENTAL STOCK TRANSFER AND TRUST COMPANY

(Jersey City, New Jersey)  

 Transfer Agent

and Registrar  

 By      

Authorized
Officer 

 
 

LIBERTY LIVEWIRE CORPORATION    
  

    The Corporation is authorized to issue Class A Common Stock, Class B Common Stock and one or more series of Preferred Stock. Each holder of
Class A Common Stock is entitled to one vote for each share of such stock held, and each holder of Class B Common Stock is entitled to ten votes for each share of such stock held, on all
matters presented to holders of Common Stock. Holders of Class A Common Stock and holders of Class B Common Stock vote together as a single class. Each share of Class B Common
Stock is convertible, at the option of the holder thereof, into one share of Class A Common Stock. 

    THE
CORPORATION WILL FURNISH TO EACH STOCKHOLDER, UPON REQUEST AND WITHOUT CHARGE, THE POWERS, DESIGNATIONS, PREFERENCES AND RELATIVE PARTICIPATING, OPTIONAL OR OTHER SPECIAL RIGHTS
OF EACH CLASS OF STOCK OR SERIES THEREOF AND THE QUALIFICATIONS, LIMITATIONS OR RESTRICTIONS OF SUCH PREFERENCES AND/OR RIGHTS. 

    The following abbreviations, when used in the inscription on the face of this certificate, shall be construed as though they were written out in
full according to applicable laws or regulations: 

	TEN COM	 	—	as tenants in common	 	UNIF GIFT MIN ACT—	 	
	 	Custodian	 	

	 	 	 	 	 	 	 	(Cust)	 	 	 	(Minor)
	TEN ENT	 	—	as tenants by the entireties	 	 	 	 	 	 	 	 
	JT TEN	 	—	as joint tenants with right

of survivorship and not as tenants in common	 	 	 	under Uniform Gifts to Minors Act
 (State)

Additional abbreviations may also be used though not in the above list 

    For
Value Received,            hereby sells, assigns and transfers unto 

	
 PLEASE INSERT SOCIAL SECURITY OR

OTHER IDENTIFYING NUMBER OF ASSIGNEE	 	 
	

Please print or typewrite name and address including postal zip code of assignee 

Shares of the capital stock represented by the within Certificate, and does hereby irrevocably constitute and 

	appoint	 	

Attorney
to transfer the said stock on the books of the within-named Corporation with full power of substitution in the premises. 

Dated,            

	NOTICE: The signature to this assignment must correspond with the name as written upon the face of the certificate in every particular, without alteration or enlargement or any change whatsoever.	 	X	 	 
 Signature

	SIGNATURE(S) GUARANTEED:	 	  
THE SIGNATURE(S) MUST BE GUARANTEED BY AN ELIGIBLE GUARANTOR INSTITUTION (BANKS, STOCKBROKERS, SAVINGS AND LOAN ASSOCIATIONS AND CREDIT UNIONS WITH MEMBERSHIP IN AN APPROVED
SIGNATURE GUARANTEE MEDALLION PROGRAM), PURSUANT TO S.E.C. RULE 17AD-15.

	KEEP THIS CERTIFICATE IN A SAFE PLACE. IF IT IS LOST, STOLEN, MUTILATED OR DESTROYED, THE CORPORATION WILL REQUIRE A BOND OF INDEMNITY AS A CONDITION TO THE ISSUANCE OF A REPLACEMENT CERTIFICATE.	 	 	 	 

QuickLinks

LIBERTY LIVEWIRE CORPORATION

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00024-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00024-of-00352.parquet"}]]