Document:

Third Amendment to Lease of Premises at 630 Fifth Avenue, New York, New York

 Exhibit 10.1 
 THIRD AMENDMENT TO LEASE 
 This THIRD AMENDMENT TO LEASE dated as of March 23, 2001 (this
“Amendment”) between RCPI TRUST, a Delaware business trust having an office c/o Tishman Speyer Properties, L.P., 45 Rockefeller Plaza, New York, New York 10111 (“Landlord”), and ANTIGENICS, INC., a
Delaware corporation having an office at 630 Fifth Avenue, New York, New York 10111 (“Tenant”). 
 WITNESSETH:

 WHEREAS, Landlord’s predecessor-in-interest, Rockefeller Center Properties, and Tenant’s predecessor-in-interest, GHA
Management Corporation, entered into that certain Lease dated December 6, 1995 (the “Original Lease”), as assigned by GHA Management Corporation to Tenant pursuant to that certain Assignment of Lease dated as of January 3,
2000, which Assignment of Lease was consented to by Landlord pursuant to that certain Consent to Assignment dated as of August 24, 2000, and as amended by (i) First Amendment to Lease, dated as of October 23, 1996 (the “First
Amendment to Lease”), and (ii) Second Amendment to Lease, dated as of February 25, 2000 (the “Second Amendment to Lease”) (as amended by the First Amendment to Lease and the Second Amendment to Lease, the
“Original Lease”), covering a portion of the 16th floor and a portion of the 21st floor (the “Original Premises”) of the building located at 630 Fifth Avenue, New York, New York (the
“Building”), all as more particularly described in the Original Lease; and 
 WHEREAS, Landlord and Tenant desire to modify
the Original Lease to (i) provide for the leasing by Tenant of a portion of the 22nd floor of the Building, designated as Space ‘C’, and being more particularly shown on Exhibit A attached hereto (the “Third Additional
Premises”), and (ii) otherwise modify the terms and conditions of the Original Lease, all as hereinafter set forth (the Original Lease, as modified by this Amendment, the “Lease”). 
 NOW, THEREFORE, in consideration of the mutual covenants herein contained, and other good and valuable consideration, the receipt and sufficiency of
which is hereby acknowledged, Landlord and Tenant agree as follows: 
 1. Capitalized Terms. All capitalized terms used and not
otherwise defined in this Amendment shall have the respective meanings ascribed to them in the Original Lease. 
 2. Lease of Third
Additional Premises. (a) Landlord hereby leases to Tenant, and Tenant hereby leases from Landlord, subject and subordinate to the Qualified Encumbrances, the Third Additional Premises for a term commencing on the date that Landlord delivers
possession of the Third Additional Premises to Tenant free of all tenancies and occupants (the “Third Additional Premises Commencement Date”) (provided, however, Tenant shall not be required to accept possession of the Third
Additional Premises prior to March 19, 2001) and ending on December 31, 2006 (the “Third Additional Premises Expiration Date”), or such earlier date upon which the term of the Lease may expire or be terminated pursuant to
any of the conditions of limitation or other provisions of the Lease or pursuant to law, upon all of the terms and conditions of the Original Lease, as modified by this Amendment. 
 (b) Landlord shall deliver possession of the Third Additional Premises to Tenant on the Third Additional Premises Commencement Date by giving Tenant
notice that the Third Additional Premises are vacant and available for Tenant’s occupancy. Landlord shall not be liable for failure to deliver possession of the Third Additional Premises to Tenant on any specified date, and such failure shall
not impair the validity of this Amendment. There shall be no postponement of the Third Additional Premises Commencement Date for any delay in the delivery of possession of the Third Additional Premises to Tenant that results from any Tenant Delay.
The provisions of this paragraph are intended to constitute “an express provision to the contrary” within the meaning of Section 223a of the New York Real Property Law or any successor Requirement. 

 (c) Effective as of the Third Additional Premises Commencement Date, Tenant shall lease the Third
Additional Premises upon all of the terms and conditions of the Original Lease, except as follows: 
 (i) The fixed rent
payable under the Lease with respect to the Third Additional Premises shall be an amount equal to $173,604.00 per annum ($14,467.00 per month) for the period commencing on the date which is three (3) months following the Third Additional
Premises Commencement Date and ending on the Third Additional Premises Expiration Date, both dates inclusive. Tenant shall pay one installment of fixed rent upon the execution and delivery of this Amendment. If the Third Additional Premises
Commencement Date is on the first day of the month, such payment shall be credited towards such month’s installment of fixed rent. If the Third Additional Premises Commencement Date is not the first day of a month, then on the Third Additional
Premises Commencement Date Tenant shall pay fixed rent for the period from the Third Additional Premises Commencement Date through the last day of such month, and the payment made by Tenant on the date of execution and delivery of this Amendment
shall be credited towards monthly fixed rent for the next succeeding calendar month. 
 (ii) The Third Additional Premises
shall be deemed to consist of 2,553 rentable square feet for all purposes of this Amendment and the Lease. 
 (iii) Tenant
shall pay all additional rent payable pursuant to the Original Lease including Article Twenty-Four hereof, except with respect to the Third Additional Premises only, (i) “Base Real Estate Taxes” shall mean the R.E. Tax
Share of the Real Estate Taxes for the Computation Year beginning on January 1, 2001 and ending on December 31, 2001 (i.e., one-half of the R.E. Tax Share of the Real Estate Taxes for the Tax Year beginning on July 1, 2000 and
ending on June 30, 2001 and one-half of the R.E. Tax Share of the Real Estate Taxes for the Tax Year beginning on July 1, 2001 and ending on June 30, 2002) and (ii) “Base COM” shall mean the O.E. Share of the
Cost of Operation and Maintenance for the Computation Year beginning on January 1, 2001 and ending on December 31, 2001. 
 (iv) Tenant has inspected the Third Additional Premises and agrees (i) to accept possession of the Third Additional Premises in their “as is” condition existing on the Third Additional Premises Commencement Date,
(ii) that neither Landlord nor Landlord’s agents have made any representations or warranties with respect to the Third Additional Premises or the Building except as expressly set forth herein, and (iii) Landlord has no obligation to
perform any work, supply any materials, incur any expense or make any alterations or improvements to the Third Additional Premises to prepare the Third Additional Premises for Tenant’s occupancy (except as expressly set forth herein).
Tenant’s occupancy of any part of the Third Additional Premises shall be conclusive evidence, as against Tenant, that (A) Tenant has accepted possession of the Third Additional Premises in their then current condition, and (B) the
Third Additional Premises and the Building are in a good and satisfactory condition as required by this Amendment. 
 (v) The
provisions of Article Thirty of the Original Lease shall apply to the Third Additional Premises, except that the reference to “$67,385.00” contained in Section 30.5 of the Original Lease shall be replaced with
“$72,760.50”. 
 (vi) Tenant shall maintain in good order and repair, the sprinkler system and fire alarm and life
safety system serving the Third Additional Premises. Such maintenance shall be performed by Tenant in accordance with the Lease, the rules and regulations and all Requirements. If the Fire Insurance Rating Organization or any Governmental Authority
or any of Landlord’s insurers requires or recommends any modifications or Alterations be made or any additional equipment be supplied in connection with the sprinkler system or fire alarm and life-safety system serving the Building or the Third
Additional Premises by reason of Tenant’s business, or the location of the partitions, trade fixtures, or other contents of the Third Additional Premises, Landlord (to the extent such modifications or Alterations are structural, affect any
Building System or involve the performance of work outside the Third Additional Premises), or Tenant (to the extent such modifications or Alterations are nonstructural, do not affect any Building System and do not involve the performance of work
outside the Third Additional Premises) shall make such modifications or Alterations, and supply such additional equipment, in either case at Tenant’s expense. 
  

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 (vii) Except as provided in this Amendment, all references in the Original Lease to the
“Premises” shall be deemed to mean the Original Premises and the Third Additional Premises for all purposes of the Lease. With respect to the Third Additional Premises only, all references in the Original Lease to “term” or
“term of this Lease” or words of similar import shall be deemed to refer to the term of the leasing of the Third Additional Premises commencing on the Third Additional Premises Commencement Date and ending on the Third Additional Premises
Expiration Date. 
 (viii) Landlord shall provide heating, ventilation and air-conditioning service to the Premises in
accordance with the provisions of Article Twenty of the Original Lease, except that such heating, ventilation and air-conditioning service shall be provided in accordance with the standards set forth in Exhibit B attached hereto during
Business Hours on Business Days. Landlord shall not be responsible if the normal operation of the Building system providing heating, ventilation and air-conditioning to the Premises (the “HVAC System”) shall fail to provide cooled
or heated air, as the case may be, in accordance with the specifications set forth in Exhibit B by reason of (x) any machinery or equipment installed by or on behalf of Tenant, which shall have an electrical load in excess of the average
electrical load and human occupancy factors for the HVAC System as designed, as the case may be, or (y) any rearrangement of partitioning or other alterations made or performed by or on behalf of Tenant. For purposes hereof, “Business
Days” shall mean all days, excluding Saturdays, Sundays and all days observed by either the State of New York, the Federal Government or the labor unions servicing the Building as legal holidays. 
 (ix) Landlord shall cause the Premises to be cleaned in accordance with the provisions of Article Twenty of the Original Lease,
except that such cleaning shall be done in accordance with the standards set forth in Exhibit C attached hereto. Any areas of the Premises requiring cleaning which Landlord is not required to clean under Section 20.1 of the
Original Lease, and any additional cleaning of any portion of the Premises requested by Tenant shall be done, at Tenant’s expense, by Landlord’s employees or Landlord’s contractor, at rates which shall be competitive with rates of
other cleaning contractors providing services to first-class office buildings in midtown Manhattan. Landlord’s cleaning personnel shall have access to the Premises at all times except between 8:00 A.M. and 5:30 P.M. on Business Days.

 (x) Third Additional Premises End of Term. (a) Expiration. Upon the Third Additional Premises Expiration
Date or the expiration or other termination of the Lease, Tenant shall quit and surrender the Third Additional Premises to Landlord, vacant, broom clean and in good order and condition, ordinary wear and tear and damage for which Tenant is not
responsible under the terms of the Lease excepted, and Tenant shall remove all of Tenant’s personal property and any alterations made by Tenant or on Tenant’s behalf within the Third Additional Premises and Center. 
 (b) Holdover Rent. Landlord and Tenant recognize that the damage to Landlord resulting from any failure by Tenant to timely
surrender possession of the Third Additional Premises may be substantial, may exceed the amount of the fixed rent and additional rent theretofore payable hereunder, and will be impossible to accurately measure. Tenant, therefore, agrees that if
possession of the Third Additional Premises is not surrendered to Landlord on or before the Third Additional Premises Expiration Date or sooner termination of the Term, in addition to any other rights or remedies Landlord may have hereunder or at
law, Tenant shall 
 (i) pay to Landlord for each month (or any portion thereof) during which Tenant holds over in the Third
Additional Premises after the Third Additional Premises Expiration Date or sooner termination of the Term, a sum equal to the greater of (1) two times the fixed rent and additional rent applicable to the Third Additional Premises payable under
the Lease for the last full calendar month of the Term, or (2) one and one-half times the fair market rental value of the Third Additional Premises for such month (as reasonably determined by Landlord); 
 (ii) be liable to Landlord for (1) any payment or rent concession which Landlord may be required to make to any tenant obtained by
Landlord for all or any part of the Third Additional Premises (a “New Tenant”) in order to induce such New Tenant not to terminate its lease by reason of the holding over by Tenant, and (2) the loss of the benefit of the
bargain if any New Tenant shall terminate its lease by reason of the holding over by Tenant; and 
  

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 (iii) indemnify Landlord against all claims for damages by any New Tenant. 

No holding over by Tenant, nor the payment to Landlord of the amounts specified above, shall operate to extend the Term. Nothing herein contained shall
be deemed to permit Tenant to retain possession of the Third Additional Premises after the Third Additional Premises Expiration Date or sooner termination of the Lease, and no acceptance by Landlord of payments from Tenant after the Third Additional
Premises Expiration Date or sooner termination of the Term shall be deemed to be other than on account of the amount to be paid by Tenant in accordance with the provisions of this clause (x). Nothing contained in this clause (x) shall be deemed
to modify the provisions of Section 25.7 of the Original Lease with respect to a holdover by Tenant in that portion of the Premises that excludes the Third Additional Premises. 
 (c) Waiver of Stay. Tenant expressly waives, for itself and for any person or entity claiming through or under Tenant, any rights
which Tenant or any such person or entity may have under the provisions of Section 2201 of the New York Civil Practice Law and Rules and of any successor law of like import then in force, in connection with any holdover summary proceedings
which Landlord may institute to enforce the foregoing provisions of this clause (x). 
 3. Modifications. Effective as of the date
hereof, the Original Lease shall be amended as follows: 
 (a) Section 6.1 (k) of the Original Lease is amended by
(i) deleting the reference to “$1,000,000” contained therein and substituting “$5,000,000” therefor; (ii) deleting the reference to “$2,000,000” contained therein and substituting “$5,000,000”
therefor; and (iii) deleting the last sentence thereof and inserting the following provision in its place: 
 “In addition, Tenant, at
Tenant’s expense, shall obtain and keep in full force and effect during the term of this Lease, (i) insurance against loss or damage by fire, and such other risks and hazards as are insurable under then available standard forms of
“all risk” property insurance policies with extended coverage, insuring Tenant’s goods, furniture and furnishings, all Fixtures removable by Tenant as provided in this Lease, and all of Tenant’s alterations and improvements to
the Premises, for the full insurable value thereof or replacement cost value thereof, having a deductible amount, if any, as reasonably determined by Landlord; (ii) during the performance of any alteration, until completion thereof,
Builder’s risk insurance on an “all risk” basis and on a completed value form including a Permission to Complete and Occupy endorsement, for full replacement value covering the interest of Landlord and Tenant (and their respective
contractors and subcontractors), any lessor of an underlying lease and any holder of an underlying mortgage in all work incorporated in the Building and all materials and equipment in or about the Premises; (iii) Workers’ Compensation
Insurance, as required by law; (iv) Business Interruption Insurance; and (v) such other insurance in such amounts as Landlord, any holder of an underlying mortgage and/or any lessor of an underlying lease may reasonably require from time
to time. All insurance required to be carried by Tenant pursuant to the terms of this Lease shall contain a provision that (x) the policy shall not be canceled unless Landlord and each additional insured shall have received 30 days’ prior
notice of the same, by certified mail, return receipt requested, (y) Tenant shall be solely responsible for the payment of all premiums under such policies and Landlord, the lessors of underlying leases and holders of underlying mortgages shall
have no obligation for the payment thereof, and (z) shall be effected under valid and enforceable policies issued by reputable and independent insurers permitted to do business in the State of New York, and rated in Best’s Insurance Guide,
or any successor thereto (or if there be none, an organization having a national reputation) as having a Best’s Rating of “A” and a “Financial Size Category” of at least “IX” or if such ratings are not then in
effect, the equivalent thereof or such other financial rating as Landlord may at any time consider appropriate. Landlord and Tenant shall each procure an appropriate clause in or endorsement to any property insurance covering the Premises, the
Building and personal property, fixtures and equipment located therein, wherein the insurance companies shall waive subrogation or consent to a waiver of right of recovery, and Landlord and Tenant agree not to make any claim against, or seek to
recover from, the other for any loss or damage to its property or the property of others resulting from fire and other hazards to the extent covered by such property insurance; provided, however, that the release, discharge, exoneration and 

  

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covenant not to sue contained herein shall be limited by and coextensive with the terms and provisions of the waiver of subrogation or waiver of right of
recovery. If the payment of an additional premium is required for the inclusion of, or consent to, a waiver of subrogation, each party shall advise the other, in writing, of the amount of any such additional premiums and the other party may pay such
additional premium. If such other party shall not elect to pay such additional premium, then the first party shall not be required to obtain such waiver of subrogation or consent to waiver. Tenant acknowledges that Landlord shall not carry insurance
on, and shall not be responsible for, (i) damage to any Alterations or improvements to the Premises, to the extent they exceed Building standard installations, (ii) any property of Tenant, and (iii) any loss suffered by Tenant due to
interruption of Tenant’s business. Tenant shall deliver to Landlord appropriate policies of insurance, including evidence of waivers of subrogation, required to be carried by it pursuant to this Lease. Evidence of each renewal or replacement of
a policy shall be delivered by Tenant to Landlord at least 10 days prior to the expiration of such policy. In lieu of the policies of insurance required to be delivered to Landlord pursuant to this paragraph (the ‘Policies’), Tenant
may deliver to Landlord a certification from Tenant’s insurance company (on the form currently designated “Acord 27”, or the equivalent, rather than on the form currently designated “Acord 25-S”, or the equivalent) which
shall be binding on Tenant’s insurance company, and which shall expressly provide that such certification (1) conveys to Landlord and any other named insured and/or additional insureds thereunder (the ‘Insured Parties’)
all the rights and privileges afforded under the Policies as primary insurance, and (2) contains an unconditional obligation of the insurance company to advise all Insured Parties in writing at least 30 days in advance of any termination of the
Policies.” 
 (b) Article Eight of the Original Lease is amended by adding the following Section 8.3 at the end thereof:

 “8-3. Fire Alarm System; Sprinklers. If due to a change in Requirements the Premises are required to be
sprinklered, Landlord may at any time during the Term install a sprinkler system and fire alarm and life safety system in the Premises. Tenant shall pay, within 30 days after demand, as Additional Rent, the cost of such installation, which cost
shall be pro-rated based on the remaining portion of the Term; provided, however, if such systems are required to be installed any time during the last 2 years of the Term, Landlord shall pay for the cost of such installation. Tenant shall afford
Landlord and its employees, contractors and agents access to the Premises at all times for the performance of such work (and there shall be no Rent abatement or allowance to Tenant for a diminution of rental value, no actual or constructive eviction
of Tenant, in whole or in part, no relief from any of Tenant’s obligations under this Lease, and no liability on the part of Landlord, by reason of inconvenience, annoyance or injury to business arising from the performance of such work).
Landlord shall use reasonable efforts to minimize interference with Tenant’s use and occupancy of the Premises during the performance of any such repair or restoration; provided, however, Landlord shall have no obligation to employ contractors
or labor at overtime or other premium pay rates or to incur any other overtime costs or additional expenses whatsoever. Tenant shall thereafter maintain in good order and repair, the sprinkler system and fire-alarm and life-safety system serving the
Premises. Such maintenance shall be performed by Tenant in accordance with this Lease, the Rules and Regulations and all Requirements. If the Fire Insurance Rating Organization or any Governmental Authority or any of Landlord’s insurers
requires or recommends any modifications or Alterations be made or any additional equipment be supplied in connection with the sprinkler system or fire alarm and life-safety system serving the Building or the Premises by reason of Tenant’s
particular manner of use of the Premises (as distinguished from general office use), or the location of the partitions, trade fixtures, or other contents of the Premises, Landlord (to the extent such modifications or Alterations are structural,
affect any Building System or involve the performance of work outside the Premises), or Tenant (to the extent such modifications or Alterations are non-structural, do not affect any Building System and do not involve the performance of work outside
the Premises) shall make such modifications or Alterations, and supply such additional equipment, in either case at Tenant’s expense.” 
 (c) Section 2(c)(iii) of the Second Amendment to Lease is amended by deleting the first reference to “Tax Year” contained therein and by substituting the reference to “Computation Year” therefor. 
  

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 (d) Article Twenty-Six of the Original Lease, Section 6 of the First Amendment to
Lease, and Section 2(c)(v) of the Second Amendment to Lease are deleted and replaced by the following: 
 “ARTICLE
TWENTY-SIX 
 SECURITY 
 Section 26.1 Security Deposit. (a) Tenant shall deposit $154,252 (the ‘Security Deposit’) with Landlord upon the execution of the Third Amendment to Lease in respect of this Lease in cash
as security for the faithful performance and observance by Tenant of the terms, covenants and conditions of this Lease, including the surrender of possession of the Premises to Landlord as herein provided. 
 (b) Landlord shall deposit the Security Deposit in a standard interest-bearing security deposit account in a bank located in New York
State. To the extent not prohibited by law, Landlord shall be entitled to receive and retain as an administrative expense an amount equal to interest on the Security Deposit at the rate of 1% per annum, which fee Landlord shall have the right
to withdraw, at any time and from time to time, as Landlord may determine. The balance of the interest shall be paid to Tenant annually, within a reasonable time following the date upon which the depository bank customarily makes interest payments.
Landlord shall not be required to credit Tenant with any interest for any period during which Landlord does not receive interest on the Security Deposit. 
 Section 26.2 Letter of Credit. In lieu of a cash deposit, Tenant may deliver the Security Deposit to Landlord in the form of a clean, irrevocable, non-documentary and unconditional
letter of credit in the amount of the Security Deposit (the ‘Letter of Credit’) issued by and drawable upon any commercial bank, trust company, national banking association or savings and loan association with offices for banking
and drawing purposes in the City of New York (the ‘Issuing Bank’), which has outstanding unsecured, uninsured and unguaranteed indebtedness, or shall have issued a letter of credit or other credit facility that constitutes the
primary security for any outstanding indebtedness (which is otherwise uninsured and unguaranteed), that is then rated, without regard to qualification of such rating by symbols such as “+” or “-” or numerical notation,
“Aa” or better by Moody’s Investors Service and “AA” or better by Standard & Poor’s Ratings Service (and is not on credit-watch with negative implications), and has combined capital, surplus and undivided
profits of not less than $500,000,000. The Letter of Credit shall (i) name Landlord as beneficiary, (ii) be in the amount of the Security Deposit, (iii) have a term of not less than one year, (iv) permit multiple drawings, (v) be
fully transferable by Landlord without the payment of any fees or charges, and (vi) otherwise be in form and content satisfactory to Landlord; provided, however, that Landlord shall in no event be obligated to accept a Letter of Credit for any
amount less than $50,000. If upon any transfer of the Letter of Credit, any fees or charges shall be so imposed, then such fees or charges shall be payable solely by Tenant and the Letter of Credit shall so specify. The Letter of Credit shall
provide that it shall be deemed automatically renewed, without amendment, for consecutive periods of one year each thereafter during the Term through the date that is at least 60 days after the Expiration Date, unless the Issuing Bank sends a notice
(the ‘Non-Renewal Notice’) to Landlord by certified mail, return receipt requested, not less than 30 days prior to the then-current expiration date of the Letter of Credit, stating that the Issuing Bank has elected not to renew the
Letter of Credit. Landlord shall have the right, upon receipt of a Non-Renewal Notice, to draw the full amount of the Letter of Credit, by sight draft on the Issuing Bank, and shall thereafter hold or apply the cash proceeds of the Letter of Credit
pursuant to the terms of this Article 26. The Letter of Credit shall state that drafts drawn under and in compliance with the terms of the Letter of Credit will be duly honored upon presentation to the Issuing Bank at an office location in
New York City. The Letter of Credit shall be subject in all respects to the International Standby Practices 1998, International Chamber of Commerce Publication No. 590. 
 Section 26.3 Application of Security. If Tenant defaults in the payment or performance of any the terms,
covenants or conditions of this Lease, including the payment of Rent, Landlord may use, apply or retain the whole or any part of the cash Security Deposit or may notify the Issuing Bank and thereupon 

  

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receive all or a portion of the Security Deposit represented by the Letter of Credit, and use, apply, or retain the whole or any part of such proceeds, as
the case may be, to the extent required for the payment of any Rent or any other sum as to which Tenant is in default, including (i) any sum which Landlord may expend or may be required to expend by reason of Tenant’s default, and (ii) any
damages or Deficiency to which Landlord is entitled pursuant to this Lease or applicable Requirements, whether such damages or Deficiency accrues before or after summary proceedings or other reentry by Landlord. If Landlord uses, applies or retains
any part of the Security Deposit, Tenant, upon demand, shall deposit with Landlord the amount so applied or retained so that Landlord shall have the full Security Deposit on hand at all times during the Term. If Tenant shall fully and faithfully
comply with all of the terms, covenants and conditions of this Lease, the Security Deposit (or so much thereof as remains) shall be returned to Tenant after the Expiration Date and after delivery of possession of the Premises to Landlord in the
manner required by this Lease. Tenant expressly agrees that Tenant shall have no right to apply any portion of the Security Deposit against any of Tenant’s obligations to pay Rent hereunder. 
 Section 26.4 Transfer. Upon a sale of the Building or the Real Property or a leasing of the Building, or any financing
of Landlord’s interest therein, Landlord shall have the right to transfer the cash Security Deposit or the Letter of Credit, as applicable, to the vendee, lessee or lender. With respect to the Letter of Credit, within 10 days after notice from
Landlord of any such anticipated sale, leasing or financing, Tenant, at its sole cost, shall arrange for the transfer of the Letter of Credit to the new landlord or lender, as designated by Landlord in the foregoing notice, or to have the Letter of
Credit reissued in the name of the new landlord or lender. Tenant shall look solely to the new landlord or lender for the return of such cash Security Deposit or Letter of Credit, and the provisions of this Section 26.4 shall apply to
every transfer or assignment made of the Security Deposit to a new landlord. Tenant will not assign or encumber, or attempt to assign or encumber, the cash Security Deposit or Letter of Credit, and neither Landlord nor its successors or assigns
shall be bound by any such actual or attempted assignment or encumbrance. 
 Section 26.5
Reduction. If Tenant (a) has not previously defaulted in its obligation to pay fixed rent or additional rent to Landlord within the time periods set forth in the Lease beyond any applicable notice and cure period,
and (b) is not then in default in the due keeping, observance or performance of any term or condition of the Lease, then, provided that Tenant complies with the provisions of this Section 26.5, on or after the 3rd anniversary of the Second
Additional Premises Commencement Date, the Security Deposit shall be reduced to $130,359.50. The Security Deposit shall be reduced as follows: (A) if the Security Deposit is in the form of cash, Landlord shall, within 30 Business Days following
notice by Tenant to Landlord that Tenant is entitled to reduce the Security Deposit pursuant to this Section 26.5, deliver to Tenant the amount by which the Security Deposit is reduced, or (B) if the Security Deposit is in the form of a
Letter of Credit, Tenant shall deliver to Landlord an amendment to the Letter of Credit (which amendment must be reasonably acceptable to Landlord in all respects), reducing the amount of the Letter of Credit by the amount of the permitted
reduction, and Landlord shall execute the amendment and such other documents as are reasonably necessary to reduce the amount of the Letter of Credit in accordance with the terms hereof. If Tenant delivers to Landlord an amendment to the Letter of
Credit in accordance with the terms hereof, Landlord shall, within 30 Business Days after delivery of such amendment, either (1) provide its reasonable objections to such amendment or (2) execute such amendment of the Letter of Credit in
accordance with the terms hereof.” 
 4. Brokerage. Each of Landlord and Tenant represents and warrants to the other that it has
not dealt with any broker in connection with this Amendment other than Tishman Speyer Properties, L.P. (“Broker”) and that, to the best of its knowledge, no other broker negotiated this Amendment or is entitled to any fee or
commission in connection herewith. Landlord shall pay Broker any commission which may be due in connection with this Amendment pursuant to a separate agreement. Each of Landlord and Tenant shall indemnify, defend, protect and hold the other party
harmless from and against any and all losses, liabilities damages, claims, judgments, fines, suits, demands, costs, interest and expenses of any kind or nature (including reasonable attorneys’ fees and disbursements) incurred in connection with
any claim, proceeding or judgment and the defense thereof which the indemnified party may incur by reason of any claim of or liability to any broker, finder or like agent (other than 

  

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Broker) arising out of any dealings claimed to have occurred between the indemnifying party and the claimant in connection with this Amendment, or the above
representation being false. The provisions of this Paragraph 4 shall survive the expiration or earlier termination of the term of the Lease. 
 5. Representations and Warranties. Tenant represents and warrants to Landlord that, as of the date hereof, (a) the Original Lease is in full force and effect and has not been modified except pursuant to this Amendment;
(b) there are no defaults existing under the Lease; (c) there exist no valid abatements, causes of action, counterclaims, disputes, defenses, offsets, credits, deductions, or claims against the enforcement of any of the terms and
conditions of the Lease; (d) this Amendment has been duly authorized, executed and delivered by Tenant and constitutes the legal, valid and binding obligation of Tenant; (e) Landlord has paid all amounts and performed all work required to
be paid or performed under the Lease in connection with Tenant’s initial occupancy of the Premises under the Lease; and (f) Landlord is not in default of any of its obligations or covenants under the Lease. 
 6. Miscellaneous. 
 (a) Except as set forth herein, nothing contained in this Amendment shall be deemed to amend or modify in any respect the terms of the Original Lease and such terms shall remain in full force and effect as modified hereby. If there is any
inconsistency between the terms of this Amendment and the terms of the Original Lease, the terms of this Amendment shall be controlling and prevail. 
 (b) This Amendment contains the entire agreement of the parties with respect to its subject matter and all prior negotiations, discussions, representations, agreements and understandings heretofore had among the
parties with respect thereto are merged herein. 
 (c) This Amendment may be executed in duplicate counterparts, each of which
shall be deemed an original and all of which, when taken together, shall constitute one and the same instrument. 
 (d) This
Amendment shall not be binding upon Landlord or Tenant unless and until Landlord shall have delivered a fully executed counterpart of this Amendment to Tenant. 
 (e) This Amendment shall be binding upon and inure to the benefit of Landlord and Tenant and their successors and permitted assigns.

 (f) This Amendment shall be governed by the laws of the State of New York without giving effect to conflict of laws
principles thereof. 
 (g) The captions, headings, and titles in this Amendment are solely for convenience of reference and
shall not affect its interpretation. 
  

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 IN WITNESS WHEREOF, Landlord, and Tenant have executed this Amendment as of the day and year first above
written. 
  

			
	 LANDLORD:

	
	RCPI TRUST
		
	By:	 	 Tishman Speyer Properties, L.P., its Agent

		
	By:	 	

		 	 Geoffrey P. Wharton
 Senior Managing Director

	
	 TENANT:

	
	ANTIGENICS, INC.
		
	By:	 	

		 	 Garo Armen
 Chief Executive Officer

  

 9 

 EXHIBIT A 
 THIRD ADDITIONAL PREMISES FLOOR PLAN 
 The floor plan that follows is intended solely to identify the
general location of the Third Additional Premises of the Building and should not be used for any other purpose. All areas, dimensions, and location’s are approximate, and any physical conditions indicated may not exist as shown. 
  

 10 

 [Floorplan graphic omitted as not material to investors; a copy will be furnished upon request.]

  

 11 

 EXHIBIT B 
 HEATING, VENTILATION AND AIR CONDITIONING SPECIFICATIONS 
 The HVAC System shall be capable of
maintaining 78 degrees Fahrenheit when summer outdoor conditions are 92 degrees Fahrenheit dry bulb and 74 degrees Fahrenheit wet bulb. The HVAC System shall be capable of maintaining 68 degrees Fahrenheit at winter outdoor conditions of 11 degrees
Fahrenheit. The HVAC System shall be capable of handling (i) an electrical usage load of not more than 4 watts per usable square foot; (ii) an occupancy rate of one (1) person per 150 usable square feet; and (iii) a ventilation
make-up rate of 20 cubic feet per minute per person with the blinds or shades drawn on the exposure subject to direct solar radiation. 
  

 12 

 EXHIBIT C 
 CLEANING SPECIFICATIONS 
 GENERAL 
 All hard surface flooring to be dust mopped nightly. All other floor maintenance shall be done at Tenant’s expense. 
 All carpeting and rugs to be carpet swept nightly and vacuumed twice monthly. 
 Hand dust nightly all furniture tops and exposed surfaces of shelves, ledges and bookcases within reach. 
 Empty and wipe clean all wastebaskets nightly and remove the contents thereof from the Premises. 
 Empty and wipe clean all ash trays and screen all sand urns nightly. 
 Wash clean all water fountains and coolers nightly. 
 Dust all door and other ventilating louvers within
reach, as necessary. 
 Dust all telephones as necessary. 
 Sweep all private stairway structures nightly. 
 All windows, interiors and exteriors, are to be washed
approximately five times per year. 
 Do all high dusting approximately once every three months, namely: 
 Dust all pictures, frames, charts, graphs and similar wall hangings not reached in nightly cleaning. 
 Dust clean all vertical surfaces, such as walls, partitions, doors, bucks and other surfaces not reached in nightly cleaning. 
 Dust clean all pipes, ventilating and air conditioning louvers, ducts, diffusers, high moldings and other high areas not reached in nightly cleaning.

 Dust all lighting fixtures, including exterior surfaces of diffusers and enclosures. 
 Dust all venetian blinds. 
 CORE
LAVATORIES 
 Sweep and wash all lavatory floors nightly, using disinfectants. 
 Wash and disinfect all basins, bowls and urinals nightly. 
 Wash and disinfect all toilet seats nightly. 
 Hand dust and clean, washing where necessary, all partitions,
tile walls, dispensers and receptacles in all lavatories and restrooms nightly. 
  

 13 

 Empty paper towel receptacles and transport wastepaper from the Premises nightly. 
 Fill toilet tissue holders nightly (tissue to be furnished by Landlord). 
 Empty sanitary disposal receptacles nightly. 
 Wash interior of wastecans and receptacles at least once a
week. 
 If core lavatory is within Tenant’s space, the soap and towel dispenser will be filled at Tenant’s direction at
Tenant’s expense. If core lavatory is on a public corridor, the soap and towel dispenser will be maintained by Landlord. 
 PUBLIC AND
CORE AREAS AND ELEVATORS 
 Dust mop all floors nightly and wash once a week. Spray buff resilient tile flooring on a semi-monthly
schedule. 
 Inspect, maintain and keep clean firehoses, extinguishers and similar equipment as necessary. 
 Spot wash walls of corridors and public stairways as necessary. 
 Empty and screen all cigarette urns daily. 
 Mop floor in public stairwells once per week. 
 Dust elevator doors and frames, and Building directories as required. 
 ******** 
 “Nightly”, as used herein, shall be exclusive of Saturdays, Sundays and
holidays. 
  

 14Fifth Supplemental Indenture

 Exhibit 4.16 
 Execution Copy 
  

 TAMPA ELECTRIC COMPANY 
 and 
 THE BANK OF NEW YORK 
 As Trustee 
  

 FIFTH SUPPLEMENTAL INDENTURE

 dated as of May 1, 2006 
 Supplementing the Indenture 
 dated as of July 1, 1998 
  

 $250,000,000 
 6.55% Notes Due 2036 
  

 TABLE OF CONTENTS 
  

					
	 	  	 	  	Page
	 ARTICLE ONE
	  	DEFINITIONS AND OTHER PROVISIONS OF GENERAL APPLICATION	  	2
			
	         Section 101.
	  	        Definitions	  	2
			
	         Section 102.
	  	        Section References	  	3
			
	 ARTICLE TWO
	  	DESIGNATION AND TERMS OF THE NOTES	  	3
			
	         Section 201.
	  	        Establishment of Series	  	3
			
	         Section 202.
	  	        Variations in Terms of the Notes	  	3
			
	         Section 203.
	  	        Amount and Denominations; the Depositary	  	4
			
	         Section 204.
	  	        Stated Maturity	  	4
			
	         Section 205.
	  	        Interest Rates and Interest Payment Dates	  	4
			
	         Section 206.
	  	        Form and Other Terms of the Notes	  	4
			
	         Section 207.
	  	        Authentication and Delivery	  	5
			
	         Section 208.
	  	        Redemption; No Sinking Fund	  	5
			
	 ARTICLE THREE
	  	MISCELLANEOUS	  	6
			
	         Section 301.
	  	        Effect On Original Indenture	  	6
			
	         Section 302.
	  	        Counterparts	  	6
			
	         Section 303.
	  	        Recitals	  	6
			
	         Section 304.
	  	        Governing Law	  	6
		
	 EXHIBIT A    FORM OF NOTE
	  	
		
	 EXHIBIT B    FORM OF SUPPLEMENTAL COMPANY ORDER
	  	

  

 -i- 

 This Fifth Supplemental Indenture, dated as of May 1, 2006, is between Tampa Electric Company, a
corporation duly organized and existing under the laws of the State of Florida (hereinafter called the “Company”) and having its principal office at TECO Plaza, 702 North Franklin Street, Tampa, Florida 33602, and The Bank of
New York, as trustee (hereinafter called the “Trustee”) and having its principal corporate trust office at 101 Barclay Street, 11th Floor East, New York, New York 10286. 
 WITNESSETH: 
 WHEREAS, the Company and the
Trustee entered into an Indenture, dated as of July 1, 1998, as amended by a Third Supplemental Indenture, dated as of June 15, 2001, between the Company and the Trustee (the “Original Indenture”), pursuant to which one or
more series of debt of the Company (the “Securities”) may be issued from time to time; and 
 WHEREAS, Section 201 of
the Original Indenture permits the terms of any series of Securities to be established in an indenture supplemental to the Original Indenture; and 
 WHEREAS, Section 901(7) of the Original Indenture provides that a supplemental indenture may be entered into by the Company and the Trustee without the consent of any Holders of the Securities to establish the form and terms of the
Securities of any series; and 
 WHEREAS, the Company has requested the Trustee to join with it in the execution and delivery of this Fifth
Supplemental Indenture in order to supplement and amend the Original Indenture by, among other things, establishing the form and terms of a series of Securities to be known as the Company’s “6.55% Notes due 2036” (the
“Notes”); and 
 WHEREAS, the Company and the Trustee desire to enter into this Fifth Supplemental Indenture for the
purposes set forth in Sections 201 and 901 of the Original Indenture as referred to above; and 
 WHEREAS, the Company has furnished the
Trustee with a Board Resolution authorizing the execution of this Fifth Supplemental Indenture; and 
 WHEREAS, all things necessary to make
this Fifth Supplemental Indenture a valid agreement of the Company and the Trustee and a valid supplement to the Original Indenture have been done, 

 NOW, THEREFORE, THIS FIFTH SUPPLEMENTAL INDENTURE WITNESSETH: 
 For and in consideration of the premises and the purchase of the Notes to be issued hereunder by holders thereof, the Company and the Trustee mutually
covenant and agree, for the equal and proportionate benefit of the respective holders from time to time of the Notes, as follows: 
 ARTICLE ONE 
 Definitions and Other Provisions of General Application 
 Section 101. Definitions 
 All capitalized terms
that are used herein and not otherwise defined herein shall have the meanings assigned to them in the Original Indenture. The Original Indenture together with this Fifth Supplemental Indenture are hereinafter sometimes collectively referred to as
the “Indenture.” 
 “Business Day” means any day other than a Saturday or Sunday that is neither a legal
holiday nor a day on which banking institutions are authorized or required by law or regulations to close in the City of New York. 
 “Comparable Treasury Issue” means the United States Treasury security selected by an Independent Investment Banker as having a maturity comparable to the remaining term of the Notes to be redeemed that would be used, at the
time of selection and in accordance with customary financial practice, in pricing new issues of corporate debt securities of comparable maturity to the remaining term of such Notes; provided, however, that if the remaining term of the Notes
to be redeemed is less than one year, the weekly average yield on actually traded United States Treasury securities adjusted to a constant maturity of one year will be used. 
 “Comparable Treasury Price” means (1) the average of five Reference Treasury Dealer Quotations for such redemption date, after
excluding the highest and lowest Reference Treasury Dealer Quotations, or (2) if an Independent Investment Banker obtains fewer than five such Reference Treasury Dealer Quotations, the average of all such quotations. 
 “Depositary” means The Depository Trust Company or its successor. 
 “Independent Investment Banker” means any of Citigroup Global Markets Inc., J.P. Morgan Securities Inc. or Morgan Stanley & Co.
Incorporated or any of their respective successors, as designated by the Company, or if all of those firms are unwilling or unable to serve as such, an independent investment and banking institution of national standing appointed by the Company.

 “Interest Payment Date” means May 15 and November 15 of each year. 
 “Notes” has the meaning set forth in Section 201 hereof. 
 “Original Issue Date” means the date upon which the Notes are initially issued by the Company, such date to be set forth on the face of
each Note. 
 “Record Date” means the fifteenth calendar day (whether or not a Business Day) immediately preceding the
related Interest Payment Date. The Record Date shall constitute the Regular Record Date for purposes of the Original Indenture. 
  

 - 2 - 

 “Reference Treasury Dealer” means: 
 (i) Citigroup Global Markets Inc., J.P. Morgan Securities Inc. and Morgan Stanley & Co. Incorporated, and each of their
respective successors; provided that, if any such Reference Treasury Dealer ceases to be a primary U.S. Government securities dealer in New York City (a “Primary Treasury Dealer”), the Company will substitute another Primary
Treasury Dealer; and 
 (ii) up to two other Primary Treasury Dealers selected by the Company. 
 “Reference Treasury Dealer Quotations” means, with respect to each Reference Treasury Dealer and any redemption date, the average, as
determined by an Independent Investment Banker, of the bid and asked prices for the Comparable Treasury Issue (expressed in each case as a percentage of its principal amount) quoted in writing to an Independent Investment Banker at 5:00 p.m., New
York City time, on the third Business Day preceding such redemption date. 
 “Treasury Rate” means, as of any redemption
date, the rate per annum equal to the semiannual equivalent yield to maturity (computed as of the second business day immediately preceding that redemption date) of the Comparable Treasury Issue, assuming a price for the Comparable Treasury Issue
(expressed as a percentage of its principal amount) equal to the Comparable Treasury Price for that redemption date. 
 Section 102. Section
References 
 Each reference to a particular section set forth in this Fifth Supplemental Indenture shall, unless the context otherwise
requires, refer to this Fifth Supplemental Indenture. 
 ARTICLE TWO 
 Designation and Terms of the Notes 
 Section 201. Establishment of Series

 There is hereby created a series of Securities to be known and designated as the “6.55% Notes due 2036” (the
“Notes”), which shall rank equally with each other and all other unsecured and unsubordinated indebtedness of the Company. For the purposes of the Original Indenture, the Notes shall constitute a single series of Securities.

 Section 202. Variations in Terms of the Notes 
 Subject to the terms and conditions set forth in the Original Indenture and in this Fifth Supplemental Indenture, the terms of any particular Note may vary from the terms of any other Note as contemplated by
Section 301 of the Original Indenture, and the terms for a particular Note will be set forth in such Note as delivered to the Trustee or an Authenticating Agent for authentication pursuant to Section 303 of the Original Indenture.

  

 - 3 - 

 Section 203. Amount and Denominations; the Depositary 
 (a) The initial principal amount of Notes that may be issued under this Fifth Supplemental Indenture shall be $250,000,000. Additional Notes may be issued
under this Fifth Supplemental Indenture in unlimited principal amounts as permitted by the Original Indenture. The authorized denominations of Notes shall be $1,000 or integral multiples of $1,000 in excess thereof. 
 (b) The Notes shall be issuable only in fully registered form, without coupons, and will initially be registered in the name of the Depositary, or its
nominee who is hereby designated as “U.S. Depositary” under the Original Indenture. 
 Section 204. Stated Maturity 
 The Stated Maturity of the principal amount of the Notes shall be May 15, 2036. 
 Section 205. Interest Rates and Interest Payment Dates 
 (a) Interest Rate. The Notes
shall bear interest at the annual rate of 6.55% from the Original Issue Date to the date on which the principal shall become due on the Stated Maturity, and if such principal is not fully paid on the Stated Maturity, until such principal is paid in
full. Interest on the Notes will be payable semi-annually on each Interest Payment Date, commencing on November 15, 2006. Such interest will be payable to the holder thereof as of the related Record Date. 
 (b) Computation of Interest. The amount of interest payable for any period will be computed on the basis of a year of 360 days consisting of
twelve 30-day months. Except for the effect of any adjustment in the Interest Payment Date as provided in the following sentence, the amount of interest payable for any period shorter than a full six-month period for which interest is computed, will
be computed on the basis of the actual number of days elapsed in such a 180-day period. If any Interest Payment Date would otherwise be a day that is not a Business Day, the payment required to be made on such Interest Payment Date will be postponed
to the next succeeding Business Day, and no interest will accrue on such payment for the period from and after such Interest Payment Date to the date of such payment on the next succeeding Business Day, except that, if such Business Day is in the
next succeeding calendar year, such payment shall be made on the immediately preceding Business Day, in each case with the same force and effect as if made on such Interest Payment Date. 
 Section 206. Form and Other Terms of the Notes 
 (a) Attached hereto as Exhibit A is the
form of Note, which form is hereby established as the form in which the Notes may be issued and which shall be completed with the series designation, Stated Maturity, interest rate and CUSIP number applicable to the Notes upon such issuance.

  

 - 4 - 

 (b) Subject to (a) above, any Note may be issued in such other form as may be provided by, or not
inconsistent with, the terms of the Original Indenture and this Fifth Supplemental Indenture. 
 Section 207. Authentication and Delivery

 As provided in and pursuant to Section 303 of the Original Indenture, each time that the Company delivers Notes to the Trustee or
Authenticating Agent for authentication after the initial issuance of Notes under this Fifth Supplemental Indenture, the Company shall deliver a Supplemental Company Order in the form of Exhibit B to this Fifth Supplemental Indenture
(which form shall be completed upon delivery with the series designation applicable to the Notes) for the authentication and delivery of such Notes and the Trustee or such Authenticating Agent shall authenticate and deliver such Notes. 

Section 208. Redemption; No Sinking Fund 
 (a)
The Notes are subject to redemption, in whole or in part, at any time, at the option of the Company, at a redemption price equal to the greater of: 
 (i) 100% of the principal amount of Notes then outstanding to be redeemed, 
 or 
 (ii) the sum of the present values of the remaining scheduled payments of principal and interest on the Notes then outstanding to be
redeemed (not including any portion of such payments of interest accrued as of the redemption date) discounted to the redemption date on a semiannual basis (computed based on a 360-day year consisting of twelve 30-day months) at the Treasury Rate,
plus 25 basis points (0.25%), as calculated by an Independent Investment Banker, 
 plus, in either of the above cases,
accrued and unpaid interest thereon to the redemption date. 
 (b) The Company will mail a notice of redemption at least 30 days but no more
than 60 days before the redemption date to each holder of Notes to be redeemed. If the Company elects to partially redeem the Notes, the Trustee will select in a fair and appropriate manner the Notes to be redeemed. 
 (c) Unless the Company defaults in payment of the redemption price, on and after the redemption date, interest will cease to accrue on the Notes or
portions thereof called for redemption. 
 (d) The Notes are not entitled to the benefit of any sinking fund or analogous provision.

  

 - 5 - 

 ARTICLE THREE 
 Miscellaneous 
 Section 301. Effect On Original Indenture 
 The Fifth Supplemental Indenture is a supplement to the Original Indenture. As supplemented by this Fifth Supplemental Indenture, the Original Indenture
is in all respects ratified, approved and confirmed, and the Original Indenture and this Fifth Supplemental Indenture shall together constitute one and the same instrument. 
 Section 302. Counterparts 
 This Fifth Supplemental Indenture may be executed in any number of
counterparts, each of which so executed shall be deemed to be an original, but all such counterparts shall together constitute one and the same instrument. 
 Section 303. Recitals 
 The recitals contained herein shall be taken as the statements of the Company, and the Trustee
assumes no responsibility for their correctness. The Trustee makes no representations as to the validity or sufficiency of this Fifth Supplemental Indenture. 
 Section 304. Governing Law 
 This Fifth Supplemental Indenture shall be governed by and construed in accordance with the
laws of the jurisdiction that govern the Original Indenture and its construction. 
 [The balance of this page intentionally left blank.]

  

 - 6 - 

 IN WITNESS WHEREOF, the parties hereto have caused this Fifth Supplemental Indenture to be duly
executed as of the date and year first written above. 
  
  

			
	TAMPA ELECTRIC COMPANY
		
	By:	 	 /s/ Sandra W. Callahan

	Name:	 	Sandra W. Callahan
	Title:	 	Vice President – Treasurer and Assistant Secretary
	
	THE BANK OF NEW YORK, AS TRUSTEE
		
	By:	 	 /s/ Van K. Brown

	Name:	 	Van K. Brown
	Title:	 	Vice President

 Signature Page of Fifth Supplemental Indenture 

 EXHIBIT A 
 FORM OF NOTE 
  

			
	 CUSIP NO.:  _________________
	 	PRINCIPAL AMOUNT: $2__,000,000
		 	
	REGISTERED NO. ____	 	

 TAMPA ELECTRIC COMPANY 
 _____% Notes Due 20__ 
  

	x	Check this box if the Note is a Global Note. 

	    	Applicable if the Note is a Global Note: 

 UNLESS THIS CERTIFICATE IS
PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY, A NEW YORK CORPORATION, TO THE ISSUER OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED IN THE NAME OF CEDE &
CO. OR IN SUCH OTHER NAME AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY (AND ANY PAYMENT IS MADE TO CEDE & CO. OR SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST
COMPANY), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL INASMUCH AS THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN. 
 This Note is a Global Security within the meaning of the Indenture hereinafter referred to and is registered in the name of Cede & Co., or such
other nominee of The Depository Trust Company, a New York corporation, or any successor depositary (“Depositary”), as requested by an authorized representative of the Depositary. This Note is exchangeable for Notes registered in the
name of a person other than the Depositary or its nominee only in the limited circumstances described in the Indenture and may not be transferred except as a whole by the Depositary to a nominee of the Depositary or by a nominee of the Depositary to
the Depositary or another nominee of the Depositary. 
  

  

					
	 ORIGINAL ISSUE DATE:
 May __, 2006
  
 ISSUE PRICE: _____% (as a

 percentage of principal
amount)
	  	 INTEREST PAYMENT DATES: _______ and ______ of each year commencing _____, 2006.
  
 SPECIFIED CURRENCY: U.S. dollars
	  	SINKING FUND: None  
 YIELD TO MATURITY: N/A

			
	 STATED MATURITY: May __, 20__
  
 INTEREST RATE: _____% per annum.
	  	AUTHORIZED DENOMINATIONS: N/A (Only applicable if specified currency is other than U.S. dollars)	  	REDEMPTION: Redeemable in
whole or in part, at the Company’s
option, from time to time at the
redemption prices described on the
reverse of this Note.  

			
		  		  	DEPOSITARY: The Depository Trust
Company, or any successor depository  

 TAMPA ELECTRIC COMPANY, a corporation duly organized and existing under the laws of the State of Florida
(herein called the “Company,” which term includes any successor corporation under the Indenture hereinafter referred to), for value received, hereby promises to pay to CEDE & CO., or registered assigns, the principal sum
set forth on the face of this Note on the Stated Maturity, upon the presentation and surrender hereof at the principal corporate trust office of The Bank of New York, or its successor in trust (the “Trustee”) or such other office as
the Trustee has designated in writing, and to pay interest on the unpaid principal balance hereof at a rate per annum (computed based on a 360-day year consisting of twelve 30-day months) equal to the Interest Rate set forth on the face of this Note
for the period from the Original Issue Date to, but excluding, the Stated Maturity. 
 Interest will be payable on the Interest Payment Dates
to the Person in whose name this Note is registered at the close of business on the related Record Date, which is the fifteenth calendar day (whether or not a Business Day) immediately preceding the related Interest Payment Date. In each case,
payments shall be made in accordance with the provisions hereof, until the principal hereof is paid or duly made available for payment. 
 Payment of the principal of (and premium, if any) and any such interest on this Note shall be made in immediately available funds at the office or agency of the Company maintained for that purpose in the City of New York in the State of New
York, in such coin or currency of the United States of America as at the time of payment is legal tender for payment of public and private debts. 
 Reference is hereby made to the further provisions of this Note set forth on the reverse hereof, which further provisions shall for all purposes have the same effect as if set forth at this place. 
 Unless the certificate of authentication hereon has been executed by the Trustee referred to on the reverse hereof by manual signature, this Note shall
not be entitled to any benefit under the Indenture or be valid or obligatory for any purpose. 

 IN WITNESS WHEREOF, TAMPA ELECTRIC COMPANY has caused this instrument to be duly executed. 
 Dated: ____________, 2006 
  

									
	 TRUSTEE’S CERTIFICATE
 OF AUTHENTICATION
	 		 	 TAMPA ELECTRIC COMPANY

	 This is one of the series
 designated therein referred
 to in the within-mentioned
 Indenture.
	 		 	 By:
	 	  
		 		 		 	 Name:
	 	
		 		 		 	 Title:
	 	
	 THE BANK OF NEW YORK,
 as Authenticating Agent for the Trustee
	 		 		 	
					
	 By:
	 	  	 		 		 	
		 	 Authorized signatory
	 		 		 	

 (REVERSE OF NOTE) 
 TAMPA ELECTRIC COMPANY 
 _____% Notes Due 20__ 
 This Note is one of a duly authorized series of securities of the Company (herein called the “Notes”), issued and to be issued under an
Indenture dated as of July 1, 1998, as supplemented by the Fifth Supplemental Indenture, dated as of May __, 2006 (as such has been or shall be amended or supplemented, the “Indenture”), between the Company and The Bank of New
York, as trustee (the “Trustee”, which term includes any successor Trustee under the Indenture), to which Indenture reference is hereby made for a statement of the respective rights, limitations of rights, duties and immunities
thereunder of the Company, the Trustee and the Holders of the Notes and of the terms upon which the Notes are, and are to be, authenticated and delivered. This Note is one of the securities of the series designated on the face hereof, in an initial
aggregate principal amount of $2__,000,000. 
 DEFINITIONS 
 The following terms, as used herein, have the following meanings unless the context or use clearly indicates another or different meaning or intent:

 “Business Day” means any day other than a Saturday or Sunday that is neither a legal holiday nor a day on which banking
institutions are authorized or required by law or regulations to close in the City of New York. 
 “Comparable Treasury
Issue” means the United States Treasury security selected by an Independent Investment Banker as having a maturity comparable to the remaining term of the Notes to be redeemed that would be used, at the time of selection and in accordance
with customary financial practice, in pricing new issues of corporate debt securities of comparable maturity to the remaining term of such Notes; provided, however, that if the remaining term of the Notes to be redeemed is less than
one year, the weekly average yield on actually traded United States Treasury securities adjusted to a constant maturity of one year will be used. 
 “Comparable Treasury Price” means (1) the average of five Reference Treasury Dealer Quotations for such redemption date, after excluding the highest and lowest Reference Treasury Dealer Quotations, or (2) if an
Independent Investment Banker obtains fewer than five such Reference Treasury Dealer Quotations, the average of all such quotations. 
 “Depositary” shall mean The Depository Trust Company or any successor depositary. 
 “Independent
Investment Banker” means any of Citigroup Global Markets Inc., J.P. Morgan Securities, Inc. or Morgan Stanley & Co. Incorporated or any of their respective successors, as designated by the Company, or if all of those firms are
unwilling or unable to serve as such, an independent investment and banking institution of national standing appointed by the Company. 

 “Interest Payment Date” means each of the dates on which interest on this Note is
payable, which dates are set forth on the face of this Note. 
 “Reference Treasury Dealer” means: 
  

	 	(i)	Citigroup Global Markets Inc., J.P. Morgan Securities Inc. and Morgan Stanley & Co. Incorporated, and each of their respective successors; provided that, if any such
Reference Treasury Dealer ceases to be a primary U.S. Government securities dealer in New York City (a “Primary Treasury Dealer”), the Company will substitute another Primary Treasury Dealer; and 

  

	 	(ii)	up to two other Primary Treasury Dealers selected by the Company. 

 “Reference Treasury Dealer Quotations” means, with respect to each Reference Treasury Dealer and any redemption date, the average, as determined by an Independent Investment Banker, of the bid and asked prices for the
Comparable Treasury Issue (expressed in each case as a percentage of its principal amount) quoted in writing to an Independent Investment Banker at 5:00 p.m., New York City time, on the third Business Day preceding such redemption date. 

“Treasury Rate” means, as of any redemption date, the rate per annum equal to the semiannual equivalent yield to maturity (computed
as of the second business day immediately preceding that redemption date) of the Comparable Treasury Issue, assuming a price for the Comparable Treasury Issue (expressed as a percentage of its principal amount) equal to the Comparable Treasury Price
for that redemption date. 
 INTEREST RATE 
 This Note will bear interest at the rate per annum (computed based on a 360-day year consisting of twelve 30-day months) identified on the face of this Note. Except for the effect of any adjustment in the Interest
Payment Date as provided in the following sentence, the amount of interest payable for any period shorter than a full six-month period for which interest is computed, will be computed on the basis of the actual number of days elapsed in such a
180-day period. If any Interest Payment Date would otherwise be a day that is not a Business Day, the payment required to be made on such Interest Payment Date will be postponed to the next succeeding Business Day, and no interest will accrue on
such payment for the period from and after such Interest Payment Date to the date of such payment on the next succeeding Business Day, except that, if such Business Day is in the next succeeding calendar year, such payment shall be made on the
immediately preceding Business Day, in each case with the same force and effect as if made on such Interest Payment Date. 
 OPTIONAL
REDEMPTION 
 The Notes are subject to redemption, in whole or in part, at any time, at the option of the Company, at a redemption price
equal to the greater of: 
  

	 	(i)	100% of the principal amount of the Notes then outstanding to be redeemed, or 

	 	(ii)	the sum of the present values of the remaining scheduled payments of principal and interest on the Notes then outstanding to be redeemed (not including any portion of such payments
of interest accrued as of the redemption date) discounted to the redemption date on a semiannual basis (computed based on a 360-day year consisting of twelve 30-day months) at the Treasury Rate, plus _____ basis points (____%), as calculated by an
Independent Investment Banker, 

 plus, in either of the above cases, accrued and unpaid interest thereon to
the redemption date. 
 The Company will mail a notice of redemption at least 30 days but no more than 60 days before the redemption date to
each holder of the Notes to be redeemed. If the Company elects to partially redeem the Notes, the Trustee will select in a fair and appropriate manner the Notes to be redeemed. 
 Unless the Company defaults in payment of the redemption price, on and after the redemption date, interest will cease to accrue on the Notes or portions
thereof called for redemption. 
 The Notes are not entitled to the benefit of any sinking fund or analogous provision. 
 TRANSFER OR EXCHANGE 
 As provided in
the Indenture and subject to certain limitations herein and therein set forth, the transfer of this Note is registerable in the Security Register, upon surrender of this Note for registration of transfer at the office or agency of the Company in any
place where the principal of (and premium, if any) and interest on this Note are payable, duly endorsed by, or accompanied by a written instrument of transfer in form satisfactory to the Company and the Security Registrar duly executed by, the
Holder hereof or his attorney duly authorized in writing, and thereupon one or more new Notes of this series and of like tenor, of authorized denominations and for the same aggregate principal amount, will be issued to the designated transferee or
transferees. 
 The Notes are issuable only in registered form without coupons and, except for such Notes issued in book-entry form, only in
denominations of $1,000 and any integral multiple of $1,000. As provided in the Indenture and subject to certain limitations herein and therein set forth, this Note is exchangeable for a like aggregate principal amount of Notes of this series and of
like tenor of a different authorized denomination, as requested by the Holder surrendering the same. 
 No service charge shall be made for
any such registration of transfer or exchange, but the Company may require payment of a sum sufficient to cover any tax or other governmental charge payable in connection therewith. 
 Prior to due presentment of this Note for registration of transfer, the Company or the Trustee and any agent of the Company or the Trustee may treat the
Person in whose name this Note is registered as the owner hereof for all purposes, whether or not this Note be overdue, and neither the Company, the Trustee nor any such agent shall be affected by notice to the contrary. 

 OTHER PROVISIONS 
 The Indenture permits, with certain exceptions as therein provided, the amendment thereof and the modification of the rights and obligations of the Company and the rights of the Holders of the Securities of each
series to be affected under the Indenture at any time by the Company and the Trustee with the consent of the Holders of a majority in principal amount of the Securities at the time Outstanding of each series to be affected and of the Holders of
66 2/3% in principal amount of the Securities at the time Outstanding of all series to be affected. The Indenture also contains provisions permitting the Holders of specified percentages in principal amount of the Securities of each series at
the time Outstanding, on behalf of the Holders of all Securities of such series, to waive compliance by the Company with certain provisions of the Indenture and certain past defaults under the Indenture and their consequences. To the extent
permitted by law, any such consent or waiver by the Holder of this Note shall be conclusive and binding upon such Holder and upon all future Holders of this Note and of any Note issued upon the registration of transfer hereof or in exchange hereof
or in lieu hereof, whether or not notation of such consent or waiver is made upon this Note. 
 No reference herein to the Indenture and no
provision of this Note or of the Indenture shall alter or impair the obligation of the Company, which is absolute and unconditional, to pay the principal of (and premium, if any) and interest on this Note at the times, place and rate, and in the
coin or currency, herein prescribed. 
 All terms used in this Note that are defined in the Indenture shall have the meanings assigned to
them in the Indenture. 
 This Note shall be governed by and construed in accordance with the laws of The State of New York. 

 ABBREVIATIONS 
 The following abbreviations, when used in the inscription on the face of this instrument, shall be construed as though they were written out in full
according to applicable laws or regulations: 
  

			
	 TEN COM —
	  	as tenants in common UNIF GIFT MIN ACT—______ CUSTODIAN_____
		  	                                       
                                        
 (Cust)                         (Minor)
		
	 TEN ENT —
	  	as tenants by the entireties
		
	 JT TEN —
	  	 as joint tenants with right of survivorship Under Uniform Gifts to Minors Act
 and   not as tenants in common ___________________________

		  	                                       
                                 (State)

 Additional abbreviations may also be used though not in the above list. 
 FOR VALUE RECEIVED, the undersigned hereby sell(s), assign(s) and transfer(s) unto 
  

			
	 Please Insert Social Security or
 Other Identifying Number of Assignee            
  
	  	 
	  	  	 

                                       
                                        
                                        
                                        
                                        
                                        
                    
 PLEASE PRINT OR TYPEWRITE NAME AND ADDRESS INCLUDING POSTAL ZIP CODE OF ASSIGNEE 
                                       
                                        
                                        
                                        
                                        
                                        
                    
                                       
                                        
                                        
                                        
                                        
                                        
                    
 the within Security of TAMPA ELECTRIC
COMPANY and does hereby irrevocably constitute and appoint __________________________________________________ attorney to transfer said Security on the books of the Company, with full power of substitution in the premises. 
  

							
	 Dated:
	 	   	    	 	    	   
		 	 	    	 	    	 
		 		    		    	  

 NOTICE: The signature to this assignment must correspond with the name as written upon the face of the within
instrument in every particular, without alteration or enlargement or any change whatsoever. 

 EXHIBIT B 
 TAMPA ELECTRIC COMPANY 
             %
NOTES DUE 20     
 SUPPLEMENTAL COMPANY ORDER 
 Pursuant to Section 207 of Article Two of the Fifth Supplemental Indenture, dated as of May 1, 2006, to the Indenture, dated as of July 1,
1998, as amended, you are instructed to prepare and authenticate a Note, of the series identified above, in the principal amount of $            . 
 IN WITNESS WHEREOF, I have hereunto set my hand this      day of
            ,     . 
  

			
	TAMPA ELECTRIC COMPANY
		
	By:	 	  

	Name:	 	
	Title:

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