Document:

EX-10.20

 EXECUTION VERSION 
  

 
  

 
  

					
		 	 Confidential Materials omitted and filed separately with the

Securities and Exchange Commission. Double asterisks denote omissions.
	  	Exhibit 10.20

 CREDIT AGREEMENT 

dated as of October 31, 2013 

among 
 DURATA THERAPEUTICS
HOLDING C.V. 
 and 
 DURATA
THERAPEUTICS INTERNATIONAL B.V., 
 as Borrowers, 

DURATA THERAPEUTICS, INC., 
 as
Parent, 
 EACH SUBSIDIARY OF PARENT PARTY HERETO, 

PDL BIOPHARMA, INC., 
 as the
Lender, 
 and 
 PDL BIOPHARMA,
INC., 
 as the Agent 
  

 
  

 

 TABLE OF CONTENTS 

 

									
	 	 	 	  	 	  	 Page
	 
			
	 Section 1.
	 	 Definitions; Interpretation
	  	 	1	  
			
	 1.1.
	 	 Definitions
	  	 	1	  
			
	 1.2.
	 	 Interpretation
	  	 	13	  
			
	 Section 2.
	 	Credit Facilities	  	 	14	  
			
	 2.1.
	 	 Loans
	  	 	14	  
		 	 2.1.1.
	  	 Loans
	  	 	14	  
		 	 2.1.2.
	  	 General
	  	 	14	  
			
	 2.2.
	 	 Loan Accounting
	  	 	14	  
		 	 2.2.1.
	  	 Recordkeeping
	  	 	14	  
		 	 2.2.2.
	  	 Notes
	  	 	14	  
			
	 2.3.
	 	 Interest
	  	 	15	  
		 	 2.3.1.
	  	 Interest Rate
	  	 	15	  
		 	 2.3.2.
	  	 Interest Payments
	  	 	15	  
		 	 2.3.3.
	  	 Computation of Interest
	  	 	15	  
			
	 2.4.
	 	 Amortization; Prepayment
	  	 	16	  
		 	 2.4.1.
	  	 Amortization
	  	 	16	  
		 	 2.4.2.
	  	 Voluntary Prepayment
	  	 	16	  
			
	 2.5.
	 	 Payment Upon Maturity
	  	 	17	  
			
	 2.6.
	 	 Making of Payments
	  	 	17	  
			
	 2.7.
	 	 Application of Payments and Proceeds
	  	 	17	  
			
	 2.8.
	 	 Payment Dates
	  	 	17	  
			
	 2.9.
	 	 Set-off
	  	 	17	  
			
	 2.10.
	 	 Currency Matters
	  	 	17	  
			
	 2.11.
	 	 Fees
	  	 	17	  
		 	 2.11.1.
	  	 Closing Fee
	  	 	17	  
		 	 2.11.2.
	  	 Change of Control Fee
	  	 	17	  
			
	 Section 3.
	 	 Yield Protection
	  	 	18	  
			
	 3.1.
	 	 Taxes
	  	 	18	  
			
	 3.2.
	 	 Increased Cost
	  	 	20	  
			
	 3.3.
	 	 Mitigation of Circumstances
	  	 	21	  
			
	 3.4.
	 	 Conclusiveness of Statements; Survival
	  	 	21	  

  
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 TABLE OF CONTENTS (continued) 

 

									
	 	 	 	  	 	  	 Page
	 
			
	 Section 4.
	 	 Conditions Precedent
	  	 	21	  
			
	 4.1.
	 	 Tranche One Loan
	  	 	21	  
		 	 4.1.1.
	  	 Delivery of Loan Documents
	  	 	21	  
		 	 4.1.2.
	  	 Payment of Fees and Expenses
	  	 	22	  
		 	 4.1.3.
	  	 Representations and Warranties
	  	 	23	  
		 	 4.1.4.
	  	 No Default
	  	 	23	  
		 	 4.1.5.
	  	 No Material Adverse Change
	  	 	23	  
		 	 4.1.6.
	  	 Repayment of Existing Obligations
	  	 	23	  
			
	 4.2.
	 	 Tranche Two Loan
	  	 	23	  
		 	 4.2.1.
	  	 Delivery of Trance Two Milestone Notice
	  	 	23	  
		 	 4.2.2.
	  	 Tranche Two Milestone
	  	 	23	  
		 	 4.2.3.
	  	 Payment of Fees and Expenses
	  	 	23	  
		 	 4.2.4.
	  	 Representations and Warranties
	  	 	23	  
		 	 4.2.5.
	  	 No Default
	  	 	24	  
		 	 4.2.6.
	  	 No Material Adverse Change
	  	 	24	  
		 	4.2.7.	  	Note	  	 	24	  
			
	 4.3.
	 	 Delayed Draw Term Loan
	  	 	24	  
		 	 4.3.1.
	  	 Delivery of Borrowing Request
	  	 	24	  
		 	 4.3.2.
	  	 Tranche Two Milestone
	  	 	24	  
		 	 4.3.3.
	  	 Payment of Fees and Expenses
	  	 	24	  
		 	 4.3.4.
	  	 Representations and Warranties
	  	 	24	  
		 	 4.3.5.
	  	 No Default
	  	 	24	  
		 	 4.3.6.
	  	 No Material Adverse Change
	  	 	24	  
		 	 4.3.7.
	  	 Note
	  	 	24	  
			
	 Section 5.
	 	Representations and Warranties	  	 	25	  
			
	 5.1.
	 	Organization	  	 	25	  
			
	 5.2.
	 	Authorization; No Conflict	  	 	25	  
			
	 5.3.
	 	 Validity; Binding Nature
	  	 	25	  
			
	 5.4.
	 	 Financial Condition
	  	 	26	  
			
	 5.5.
	 	 No Material Adverse Change
	  	 	26	  
			
	 5.6.
	 	 Litigation
	  	 	26	  
			
	 5.7.
	 	 Ownership of Properties; Liens
	  	 	26	  
			
	 5.8.
	 	 Capitalization; Subsidiaries
	  	 	26	  
			
	 5.9.
	 	 Pension Plans
	  	 	27	  
			
	 5.10.
	 	 Compliance with Law; Investment Company Act; Other Regulated Entities
	  	 	27	  
			
	 5.11.
	 	 Margin Stock
	  	 	27	  
			
	 5.12.
	 	 Taxes
	  	 	27	  
			
	 5.13.
	 	 Solvency
	  	 	28	  

  
 ii 

 TABLE OF CONTENTS (continued) 

 

									
	 	 	 	  	 	  	 Page
	 
			
	 5.14.
	 	 Environmental Matters
	  	 	28	  
			
	 5.15.
	 	 Insurance
	  	 	29	  
			
	 5.16.
	 	 Information
	  	 	29	  
			
	 5.17.
	 	 Intellectual Property
	  	 	29	  
			
	 5.18.
	 	 Labor Matters
	  	 	29	  
			
	 5.19.
	 	 No Default
	  	 	30	  
			
	 5.20.
	 	 Foreign Assets Control Regulations and Anti-Money Laundering
	  	 	30	  
		 	5.20.1.	  	 OFAC
	  	 	30	  
		 	5.20.2.	  	 Patriot Act
	  	 	30	  
			
	 5.21.
	 	 [Reserved]
	  	 	30	  
			
	 5.22.
	 	 Internal Controls
	  	 	30	  
			
	 Section 6.
	 	Affirmative Covenants	  	 	31	  
			
	 6.1.
	 	 Information
	  	 	31	  
		 	6.1.1.	  	 Annual Report
	  	 	31	  
		 	6.1.2.	  	 Quarterly Reports
	  	 	31	  
		 	6.1.3.	  	 [Reserved]
	  	 	31	  
		 	6.1.4.	  	 Compliance Certificate
	  	 	31	  
		 	6.1.5.	  	 Notice of Default; Litigation; ERISA Matters
	  	 	31	  
		 	6.1.6.	  	 [Reserved]
	  	 	32	  
		 	6.1.7.	  	 Budgets
	  	 	32	  
		 	6.1.8.	  	 Other Information
	  	 	32	  
			
	 6.2.
	 	 Books; Records; Inspections
	  	 	32	  
			
	 6.3.
	 	Maintenance of Property; Insurance; Intellectual Property	  	 	32	  
			
	 6.4.
	 	Compliance with Laws and Contractual Obligations; Payment of Taxes and Liabilities	  	 	34	  
			
	 6.5.
	 	Maintenance of Existence	  	 	34	  
			
	 6.6.
	 	Environmental Matters	  	 	34	  
			
	 6.7.
	 	Further Assurances	  	 	34	  
			
	 6.8.
	 	Internal Controls	  	 	36	  
			
	 6.9.
	 	Tranche Two Milestone Notice	  	 	36	  
			
	 6.10.
	 	Conference Calls	  	 	36	  
			
	 6.11
	 	Post-Closing Obligations	  	 	36	  
			
	 Section 7.
	 	Negative Covenants	  	 	37	  
			
	 7.1.
	 	Debt	  	 	37	  

  
 iii 

 TABLE OF CONTENTS (continued) 

 

									
	 	 	 	  	 	  	 Page
	 
			
	 7.2.
	 	Liens	  	 	39	  
			
	 7.3.
	 	Restricted Payments	  	 	40	  
			
	 7.4.
	 	Mergers; Consolidations; Asset Sales	  	 	41	  
			
	 7.5.
	 	Modification of Organizational Documents	  	 	42	  
			
	 7.6.
	 	Use of Proceeds	  	 	42	  
			
	 7.7.
	 	Transactions with Affiliates	  	 	42	  
			
	 7.8.
	 	Inconsistent Agreements	  	 	43	  
			
	 7.9.
	 	Business Activities	  	 	43	  
			
	 7.10.
	 	Investments	  	 	43	  
			
	 7.11.
	 	Fiscal Year	  	 	44	  
			
	 7.12.
	 	Deposit Accounts and Securities Accounts	  	 	44	  
			
	 7.13.
	 	Sale-Leasebacks	  	 	45	  
			
	 7.14
	 	Hazardous Substances	  	 	45	  
			
	 7.15.
	 	ERISA Liability	  	 	45	  
			
	 7.16.
	 	Liquidity	  	 	45	  
			
	 Section 8.
	 	Events of Default; Remedies	  	 	45	  
			
	 8.1.
	 	Events of Default	  	 	45	  
		 	8.1.1.	  	Non-Payment of Credit Agreement	  	 	45	  
		 	8.1.2.	  	Default Under Other Debt	  	 	45	  
		 	8.1.3.	  	Bankruptcy; Insolvency	  	 	46	  
		 	8.1.4.	  	Non-Compliance with Loan Documents	  	 	46	  
		 	8.1.5.	  	Representations; Warranties	  	 	46	  
		 	8.1.6.	  	Judgments	  	 	46	  
		 	8.1.7	  	Invalidity of Collateral Documents	  	 	47	  
		 	8.1.8.	  	Invalidity of Subordination Provisions	  	 	47	  
		 	8.1.9.	  	Change of Control	  	 	47	  
			
	 8.2.
	 	Remedies	  	 	47	  
			
	 Section 9.
	 	The Agent	  	 	48	  
			
	 9.1.
	 	Appointment; Authorization	  	 	48	  
			
	 9.2.
	 	Delegation of Duties	  	 	48	  
			
	 9.3.
	 	Limited Liability	  	 	48	  
			
	 9.4.
	 	Successor Agent	  	 	48	  
			
	 9.5.
	 	Collateral Matters	  	 	49	  

  
 iv 

 TABLE OF CONTENTS (continued) 

 

									
	 	 	 	  	 	  	 Page
	 
			
	 Section 10.
	 	Miscellaneous	  	 	49	  
			
	 10.1.
	 	Waiver; Amendments	  	 	49	  
			
	 10.2.
	 	Notices	  	 	50	  
			
	 10.3.
	 	Costs; Expenses	  	 	50	  
			
	 10.4.
	 	Indemnification by the Borrower	  	 	50	  
			
	 10.5.
	 	Marshaling; Payments Set Aside	  	 	51	  
			
	 10.6.
	 	Nonliability of the Lender	  	 	51	  
			
	 10.7.
	 	Confidentiality	  	 	51	  
			
	 10.8.
	 	Captions	  	 	52	  
			
	 10.9.
	 	Nature of Remedies	  	 	52	  
			
	 10.10.
	 	Counterparts	  	 	52	  
			
	 10.11.
	 	Severability	  	 	52	  
			
	 10.12.
	 	Entire Agreement	  	 	52	  
			
	 10.13.
	 	Successors; Assigns	  	 	52	  
			
	 10.14.
	 	Governing Law	  	 	53	  
			
	 10.15.
	 	Forum Selection; Consent to Jurisdiction; Service of Process	  	 	53	  
			
	 10.16.
	 	Waiver of Jury Trial	  	 	53	  
			
	 10.17.
	 	Collateral Agent	  	 	54	  
			
	 10.18.
	 	Limitation of Liability	  	 	54	  

  
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 TABLE OF CONTENTS (continued) 

 

			
	Annexes	  	
		
	Annex I	  	Addresses

  

			
	Exhibits	  	
		
	Exhibit A	  	Form of Compliance Certificate
	Exhibit B	  	Form of Note
	Exhibit C	  	Form of Intellectual Property Security Agreements

  
 vi 

 CREDIT AGREEMENT 

This Credit Agreement dated as of October 31, 2013 (as amended, restated, supplemented or otherwise modified from time to time, this
“Agreement”), is made among DURATA THERAPEUTICS HOLDING C.V., a limited partnership organized under the laws of the Netherlands (“Durata C.V.”), DURATA THERAPEUTICS INTERNATIONAL B.V., a private company with limited
liability incorporated under the laws of the Netherlands having its official seat in Amsterdam, the Netherlands, and which is registered with the Dutch trade register under number 55527221 (“Durata B.V.” and together with Durata
C.V., each a “Borrower” and collectively, the “Borrowers”), DURATA THERAPEUTICS, INC., a Delaware corporation (“Parent”), PDL BIOPHARMA, INC., a Delaware corporation (the “Lender”),
each Subsidiary of Parent from time to time party hereto and PDL BIOPHARMA, INC., a Delaware corporation, not individually, but as the Agent (as defined below). 

Parent and each Borrower have agreed to enter into this Agreement with the Lender and the Agent evidencing each Borrower’s agreement to
incur the Loans, and in connection therewith, to make the representations and warranties, covenants and undertakings as hereinafter set forth. 
  

	Section 1.	Definitions; Interpretation. 

 1.1. Definitions. When used herein the following
terms shall have the following meanings: 
 “Acquisition” means any transaction or series of related transactions for the
purpose of or resulting, directly or indirectly, in (a) the acquisition of all or substantially all of the assets of a Person, or of all or substantially all of any business or division of a Person, (b) the acquisition of in excess of 50%
of the Stock of any Person, or otherwise causing any Person to become a Subsidiary, (c) a merger, consolidation, amalgamation or any other combination with another Person (other than a combination between two Persons that prior to the merger,
consolidation, amalgamation or combination were already Loan Parties) and (d) the acquisition of a brand, line of business, division, branch, product line, marketing rights, patent rights or other Intellectual Property rights with respect to a
product line, operating division, product or potential product, or other unit operation of any Person. 
 “Affiliate” of
any Person means (a) any other Person which, directly or indirectly, controls or is controlled by or is under common control with such Person and (b) any officer or director of such Person. A Person shall be deemed to be “controlled
by” any other Person if such Person possesses, directly or indirectly, power to vote 10% or more of the securities (on a fully diluted basis) having ordinary voting power for the election of directors or managers or power to direct or cause the
direction of the management and policies of such Person whether by contract or otherwise. Unless expressly stated otherwise herein, neither the Agent nor the Lender shall be deemed an Affiliate of any Loan Party. 

“Agent” means PDL BioPharma, Inc. in its capacity as administrative agent for the Lender hereunder and any successor thereto
in such capacity. 
 “Agreement” has the meaning set forth in the Preamble. 

  
 1 

 “Applicable Law” means all applicable provisions of all (i) constitutions,
treaties, statutes, laws, rules, regulations and ordinances of any Governmental Authority, (ii) authorizations, consents, approvals, permits or licenses issued by, or a registration or filing with, any Governmental Authority and
(iii) orders, decisions, judgments, awards and decrees of any Governmental Authority (including common law and principles of public policy). 

“Assistance Agreement” means that certain Assistance Agreement by and between Parent and the State of Connecticut (acting by
the Department of Economic and Community Development) dated as of May 2013, and the related security agreement, each as amended from time to time. 

“Audit Costs” means the reasonable out-of-pocket costs of any audit of the books and records of Parent and its Subsidiaries
with respect to amounts paid or payable under this Agreement, including all reasonable fees and expenses incurred in connection therewith. 

“Borrower” has the meaning set forth in the Preamble. 

“Borrowing Request” has the meaning set forth in Section 2.1.1(c). 

“Business Day” means any day on which commercial banks are open for commercial banking business in New York, New York. 

“Capital Lease” means, with respect to any Person, any lease of (or other agreement conveying the right to use) any real or
personal property by such Person that, in conformity with GAAP, as in effect on the Closing Date, is accounted for as a capital lease on the balance sheet of such Person. 

“Capital Stock” means, with respect to any Person, the Stock and Stock Equivalents of such Person. 

“Cash Equivalent Investment” means, at any time, (a) any evidence of Debt, maturing not more than one year after such
time, issued or guaranteed by the United States Government or any agency thereof, (b) commercial paper, or corporate demand notes, in each case rated at least A-l by Standard & Poor’s Ratings Group or P-l by Moody’s Investors
Service, Inc., (c) any certificate of deposit (or time deposit represented by a certificate of deposit) or banker’s acceptance maturing not more than one year after such time, or any overnight Federal Funds transaction that is issued or
sold by a commercial banking institution that is a member of the Federal Reserve System and has a combined capital and surplus and undivided profits of not less than $500,000,000, (d) any repurchase agreement entered into with any commercial
banking institution of the nature referred to in clause (c) above which (i) is secured by a fully perfected security interest in any obligation of the type described in any of clauses (a) through (c) above and (ii) has a
market value at the time such repurchase agreement is entered into of not less than 100% of the repurchase obligation of such commercial banking institution thereunder, (e) money market accounts or mutual funds which invest predominantly in
assets satisfying the foregoing requirements and (f) other short term liquid investments consistent with the Borrower’s investment policy as in effect on the Closing Date. 

“CFC” has the meaning set forth in Section 10.18. 

  
 2 

 “Change of Control” means an event or series of events by which: 

(a) the acquisition of beneficial ownership, directly or indirectly, by any Person or group (within the meaning of the Securities Exchange Act
of 1934 and the rules of the Securities & Exchange Commission thereunder as in effect on the date hereof) of Capital Stock representing more than 49% of the aggregate ordinary voting power represented by the issued and outstanding Capital
Stock of Parent; or 
 (b) all or substantially all of the assets of Parent or any Borrower are disposed of in any one or more related
transactions. 
 “Closing Date” means the date on which the conditions set forth in Section 4.1 have been
satisfied or waived by the Lender in its sole discretion. 
 “Closing Fee” means the fee due from the Borrower to the Agent
on or before the Closing Date in an amount equal to [**]% of the aggregate principal amount of the Tranche One Commitment. 

“Collateral” means all property and interests in property and proceeds thereof now owned or hereafter acquired by any Loan
Party and any other Person who has granted a Lien to the Agent, in or upon which a Lien now or hereafter exists in favor of the Lender or the Agent for the benefit of the Agent and the Lender, whether under this Agreement or under any other
documents executed by any such Persons and delivered to the Agent. 
 “Collateral Access Agreement” means an agreement in
form and substance satisfactory to the Agent in its reasonable discretion pursuant to which a lessor of real property on which Collateral is stored or otherwise located, or a warehouseman, processor or other bailee of inventory or other property
owned by any Loan Party, acknowledges the Liens of the Agent and provides access to any such Collateral, inventory or other property, which agreement will contain additional waivers or subordination approved by the Agent in its reasonable
discretion. 
 “Collateral Documents” means, collectively, the Security Agreement (including as may be supplemented by the
joinder of any Subsidiary of Parent thereto), any Subsidiary Guaranty, the Dutch Security Documents, the UK Share Charge Documents and each other agreement or instrument pursuant to or in connection with which any Loan Party or any other Person
grants a security interest in any Collateral to the Agent for the benefit of the Lender or pursuant to which any such security interest in Collateral is perfected, each as amended, restated or otherwise modified from time to time in accordance with
the terms hereof and thereof. 
 “Commitments” means the Tranche One Commitment, the Tranche Two Commitment and the Delayed
Draw Commitment. 
 “Compliance Certificate” means a certificate substantially in the form of Exhibit A. 

“Connecticut Assets” are all furniture, laptops, telepresence systems and phone lines of Parent located in Connecticut or
Illinois, all silhouette cameras of Parent located in Connecticut or purchased in connection with DISCOVER-1 or DISCOVER-2 studies and all televisions of Parent located in Illinois, whether now owned or hereafter acquired at any time by Parent or in

  
 3 

 
which Parent now has or at any time in the future may acquire any right, title or interest, all proceeds (including condemnation proceeds), all accessions and additions thereto, and all
substitutions and replacements therefor and products of any and all of the foregoing; in each case to the extent such assets are pledged by Parent to the State of Connecticut Acting by the Department of Economic and Community Development as set
forth in the Assistance Agreement substantially in the form provided to Agent prior to the Closing Date, for so long as such grant is in effect. 

“Connection Income Taxes” means Other Connection Taxes that are imposed on or measured by net income (however denominated) or
that are franchise Taxes or branch profits Taxes. 
 “Contingent Obligation” means any agreement, undertaking or
arrangement by which any Person guarantees, endorses or otherwise becomes or is contingently liable upon (by direct or indirect agreement, contingent or otherwise, to provide funds for payment, to supply funds to or otherwise to invest in a debtor,
to provide security for the obligations of a debtor or otherwise to assure a creditor against loss) any indebtedness, obligation or other liability of any other Person (other than by endorsements of instruments in the course of collection), or
guarantees the payment of dividends or other distributions upon the Stock of any other Person. The amount of any Person’s obligation in respect of any Contingent Obligation shall (subject to any limitation set forth therein) be deemed to be the
principal amount of the indebtedness, obligation or other liability supported thereby or the amount of the dividends or distributions guaranteed, as applicable. 

“Control Agreement” means a tri-party deposit account, securities account or commodities account Control Agreement by and
among the applicable Loan Party, the Agent and the depository, securities intermediary or commodities intermediary, and each in form and substance reasonably satisfactory to the Agent and in any event providing to the Agent “control” of
such deposit account, securities or commodities account within the meaning of Articles 8 and 9 of the UCC. 
 “Copyrights”
means all rights, title and interests (and all related IP Ancillary Rights) arising under any Applicable Law in copyrights and all mask work, database and design rights, whether or not registered or published, all registrations and recordations
thereof and all applications in connection therewith. 
 “Debt” of any Person means, without duplication, (a) all
indebtedness of such Person for borrowed money, (b) all indebtedness evidenced by bonds, debentures, notes or similar instruments, (c) all obligations of such Person as lessee under Capital Leases which have been or should be recorded as
liabilities on a balance sheet of such Person in accordance with GAAP as in effect on the date hereof, (d) all obligations of such Person to pay the deferred purchase price of property or services (excluding trade accounts payable in the
ordinary course of business), (e) all indebtedness secured by a Lien on the property of such Person, whether or not such indebtedness shall have been assumed by such Person (with the amount thereof being measured as the fair market value of
such property), (f) all obligations, contingent or otherwise, with respect to letters of credit (whether or not drawn), banker’s acceptances and surety bonds issued for the account of such Person, (g) all Hedging Obligations of such
Person, (h) all Contingent 

  
 4 

 
Obligations of such Person, (i) earn-out, purchase price adjustment and similar obligations, (j) all obligations of such Person in respect of Disqualified Capital Stock issued by such
Person, (k) all indebtedness of the types listed in (a) through (j) and (l) of any partnership of which such Person is a general partner and (l) all obligations of such Person under any synthetic lease transaction, where
such obligations are considered borrowed money indebtedness for tax purposes but the transaction is classified as an operating lease in accordance with GAAP. 

“Default” means any event that, if it continues uncured, will, with the lapse of time or the giving of notice or both,
constitute an Event of Default. 
 “Default Rate” has the meaning set forth in Section 2.3.1. 

“Delayed Draw Commitment” means, as to the Lender, the Lender’s commitment to provide the Delayed Draw Term Loan in the
aggregate principal amount of $30,000,000 pursuant to Section 2.1.1(c). 
 “Delayed Draw Term Loan” means the term
loan from the Lender in a principal amount of up to $30,000,000 made to the Borrower pursuant to Section 2.1.1(b). 

“Disclosure Letter” means the letter dated as of the date of this Agreement delivered by the Loan Parties to the Agent and
the Lender in connection with the execution and delivery of this Agreement. 
 “Disqualified Capital Stock” means any Stock
which, by its terms (or by the terms of any security into which it is convertible or for which it is exchangeable), or upon the happening of any event, (a) matures (excluding any maturity as the result of an optional redemption by the issuer
thereof) or is mandatorily redeemable or is redeemable at the option of the holder thereof, in whole or in part, on or prior to January 31, 2019 or (b) is convertible into or exchangeable (unless at the sole option of the issuer thereof)
for (i) debt securities or (ii) any Stock referred to in (a) above, in each case at any time on or prior to January 31, 2019. 

“Dollar” and “$” mean lawful currency of the United States of America. 

“Durata U.S.” means Durata Therapeutics U.S. Limited, a Delaware corporation 

“Durata UK” means Durata Therapeutics Limited, an entity organized under the laws of England and Wales, and a Wholly-Owned
Subsidiary of Durata B.V. 
 “Dutch Security Documents” means (a) that certain Security Agreement by and among Durata
B.V., Durata C.V., Parent and the Agent, (b) that certain Deed of Pledge of Shares (in the capital of Durata B.V.), in respect of the equity interests of Durata B.V (c) that certain Deed of Pledge of Partnership Interests by and among
Parent and Vicuron, as pledgers, the Agent, as pledgee, and Durata C.V., as partnership, in respect of the partnership interests in Durata C.V. and (d) any other documents and instruments requested by the Agent, in each case, in form and
substance acceptable to the Agent. 
 “Eligible Institution” means any Person that is a bank, institutional lender or other
recognized financing provider. 

  
 5 

 “Environmental Claims” means all claims, however asserted, by any governmental,
regulatory or judicial authority or other Person alleging potential liability or responsibility under or for violation of any Environmental Law, or for release or injury to the environment or any Person or property or natural resources. 

“Environmental Laws” means all present or future federal, state, provincial or local laws, statutes, common law duties,
rules, regulations, ordinances and codes, including all amendments, together with all administrative orders, directed duties, requests, licenses, authorizations and permits of, and agreements with, any Governmental Authority, in each case relating
to any matter arising out of or relating to health and safety, or pollution or protection of the environment, natural resources or the workplace, including any of the foregoing relating to the presence, use, production, recycling, reclamation,
generation, handling, transport, treatment, storage, disposal, distribution, discharge, release, emission, control, cleanup or investigation or management of any Hazardous Substance. 

“ERISA” means the Employee Retirement Income Security Act of 1974, as amended. 

“Event of Default” means any of the events described in Section 8.1. 

“Excluded Inventory” means any items of Inventory which consist of unfinished active pharmaceutical ingredients and are
maintained or stored in a particular location for a period of no longer than ninety (90) days all of which such Inventory is then (a) immediately transferred to a location in which a bailee or landlord waiver is in place (to the extent
that a bailee or landlord waiver is required pursuant to the terms hereof) or (b) otherwise sold. 
 “Excluded Taxes”
means any of the following Taxes imposed on or with respect to the Lender or required to be withheld or deducted from a payment to the Lender: (a) Taxes imposed on or measured by the Lender’s net income (however denominated), franchise
Taxes, and branch profits Taxes, in each case (i) imposed by the jurisdiction under which the Lender is organized or has its principal office or applicable lending office or (ii) that are Other Connection Taxes, (b) U.S. federal
withholding taxes pursuant to a law in effect at the time such Lender first becomes a party to this Agreement or changes its lending office, except to the extent that, pursuant to Section 3.1(a), amounts with respect to such Taxes were payable
to such Lender’s assignor immediately before such Lender became a party hereto or to such Lender immediately before it changed its lending office, (c) Taxes attributable to Lender’s failure to comply with Section 3.1(d)
and (d) any U.S. federal withholding taxes imposed pursuant to FATCA. 
 “Existing Loan Documents” means that certain
Loan and Security Agreement dated as of March 5, 2013, among Oxford Finance, LLC, a Delaware limited liability company, the lenders party thereto from time to time, each of the Borrowers and Parent, and all documents and instruments executed
and delivered from time to time in connection therewith. 
 “Existing Obligations” means all obligations, including accrued
interest, outstanding pursuant to the Existing Loan Documents. 
 “FATCA” means Sections 1471 through 1474 of the Code, as
of the date of this Agreement (or any amended or successor provision that is substantively comparable and not materially more burdensome to comply with), and any current or future regulations issued thereunder or official interpretations thereof.

  
 6 

 “Fiscal Quarter” means a fiscal quarter of a Fiscal Year. 

“Fiscal Year” means the fiscal year of Parent and its Subsidiaries, which period shall be the 12-month period ending on
December 31 of each year. 
 “FRB” means the Board of Governors of the Federal Reserve System or any successor
thereto. 
 “GAAP” means generally accepted accounting principles as in effect in the United States of America and, in
relation to any Borrower incorporated under Netherlands law, generally accepted accounting principles in the Netherlands, including IFRS, in each case, which are applicable to the circumstances as of the date of determination. 

“Governmental Authority” means any nation or government, any state, province, municipality or other political subdivision
thereof, any central bank (or similar monetary or regulatory authority) thereof, any entity exercising executive, legislative, judicial, regulatory or administrative functions of or pertaining to government (including any supra-national bodies such
as the European Union or the European Central Bank), and any corporation or other entity owned or controlled, through stock or capital ownership or otherwise, by any of the foregoing. 

“Hazardous Substances” means any waste, chemical, substance, or material listed, defined, classified, or regulated as a
hazardous waste, hazardous substance, pollutant, contaminant, toxic substance, or hazardous, dangerous or radioactive material, chemical or waste or any waste, chemical, substance, or material otherwise regulated by any Environmental Law, including,
without limitation, any petroleum or any derivative, waste, or byproduct thereof, radon, asbestos, and polychlorinated biphenyls, and any other substance, the storage, manufacture, disposal, treatment, generation, use, transportation, remediation,
release into or concentration in the environment of which is prohibited, controlled, regulated or licensed by any governmental authority under any Environmental Law. 

“Hedging Obligation” means, with respect to any Person, any liability of such Person under any interest rate, currency or
commodity swap agreement, cap agreement or collar agreement, and any other agreement or arrangement designed to protect a Person against fluctuations in interest rates, currency exchange rates or commodity prices. The amount of any Person’s
obligation in respect of any Hedging Obligation shall be deemed to be the net termination value thereof as of such date. 

“Holders” means, collectively, the holders of the Capital Stock of Parent as of the Closing Date, each natural relative who
is a rightful heir of the foregoing, and any trust maintained by or for the benefit of any of the foregoing. 
 “Indemnified
Liabilities” has the meaning set forth in Section 10.4. 

  
 7 

 “Indemnified Taxes” means (a) Taxes, other than Excluded Taxes, imposed on
or with respect to any payment made by or on account of any obligation of any Loan Party under any Loan Document and (b) to the extent not otherwise described in (a), Other Taxes. 

“Intellectual Property” means all rights, title and interests in intellectual property arising under any Applicable Law and
all IP Ancillary Rights relating thereto, including all Copyrights, Patents, Trademarks, Internet Domain Names, Trade Secrets, industrial designs, integrated circuit topographies, and rights under IP Licenses. 

“Interest-Only Period” shall mean the period beginning on the Closing Date and continuing through the fifth (5th) (or 4th if the Closing Date is an Interest Payment Date) Interest Payment Date after the Closing Date. 

“Interest Payment Date” means the last Business Day of each March, June, September and December. 

“Internet Domain Name” means all right, title and interest (and all related IP Ancillary Rights) arising under any Applicable
Law in internet domain names. 
 “Investment” means, with respect to any Person, (a) the purchase or other acquisition
of any debt or equity security of any other Person, (b) the making of any loan, advance or capital contribution to any other Person, (c) becoming obligated with respect to a Contingent Obligation in respect of obligations of any other
Person or (d) the making of an Acquisition. 
 “IP Ancillary Rights” means, with respect to an item of Intellectual
Property, all foreign counterparts to, and all divisionals, reversions, continuations, continuations-in-part, reissues, reexaminations, renewals and extensions of, such Intellectual Property and all income, royalties, proceeds and liabilities at any
time due or payable or asserted under or with respect to any of the foregoing or otherwise with respect to such Intellectual Property, including all rights to sue or recover at law or in equity for any past, present or future infringement,
misappropriation, dilution, violation or other impairment thereof, and, in each case, all rights to obtain any other IP Ancillary Right. 

“IP License” means all contractual obligations (and all related IP Ancillary Rights), whether written or oral, granting any
right, title and interest in any Intellectual Property. 
 “IRC” means the Internal Revenue Code of 1986, as amended. 

“IRS” has the meaning set forth in Section 3.1(d). 

“Legal Costs” means, with respect to any Person, (a) all reasonable fees and charges of any counsel, accountants,
auditors, appraisers, consultants and other professionals to such Person and (b) all court costs and similar reasonable legal expenses. 

“Lender Party” has the meaning set forth in Section 10.4. 

“Lender” has the meaning set forth in the Preamble. 

  
 8 

 “Lien” means, with respect to any Person, any interest granted by such Person in
any real or personal property, asset or other right owned or being purchased or acquired by such Person which secures payment or performance of any obligation and shall include any mortgage, lien, encumbrance, charge or other security interest of
any kind, whether arising by contract, as a matter of law, by judicial process or otherwise. 
 “Liquidity” means, at any
time, the aggregate amount of cash and Cash Equivalent Investments held by Parent and any of its domestic Subsidiaries at such time (in US deposit accounts that are subject to Control Agreements in form and substance reasonably satisfactory to the
Agent) that are not (A) subject to any Liens (other than Liens under the Collateral Documents and customary setoff rights with respect to deposit accounts or other funds maintained with depository institutions that are created by law or by
applicable account agreements in favor of such depositary institutions or securities intermediaries), (B) required to be maintained or kept segregated from the general assets of Parent or the applicable Subsidiary for the purpose of securing or
providing a source of payment for Debt or other obligations that are or from time to time may be owed to one or more creditors of Parent or any Subsidiary (other than to secure the Obligations) or (C) held by a Subsidiary (other than a Loan
Party) that is subject to restrictions on its ability to pay dividends or distributions. 
 “Loans” means the Tranche One
Loan, the Tranche Two Loan and the Delayed Draw Term Loan. 
 “Loan Documents” means (a) this Agreement, the Notes,
the Collateral Documents, the Perfection Certificate, the Disclosure Letter, any subordination agreements and (b) all other documents, instruments and agreements delivered in connection with the foregoing, all as amended, restated or otherwise
modified from time to time in accordance with the terms hereof and thereof. 
 “Loan Party” means Parent, each Borrower and
each Subsidiary of Parent that has executed and delivered a Subsidiary Guaranty and Security Agreement. 
 “Margin Stock”
means any “margin stock” as defined in Regulation T, U or X of the FRB. 
 “Material Adverse Effect” means
(a) a material adverse change in, or a material adverse effect upon, the operations, assets, business, properties or condition (financial or otherwise) of Parent and the Loan Parties taken as a whole, (b) a material impairment of the
ability of any Loan Party to perform in any material respect any of its Obligations under any Loan Document to which it is a party or (c) a material adverse effect upon the legality, validity, binding effect or enforceability against any Loan
Party of any Loan Document. 
 “Maturity Date” means October 31, 2018. 

“Note” means a promissory note in the form attached hereto as Exhibit B, as the same may be replaced, substituted,
amended, restated or otherwise modified from time to time. 
 “Obligations” means all liabilities, indebtedness and
obligations (including interest accrued at the rate provided in the applicable Loan Document after the commencement of a 

  
 9 

 
bankruptcy proceeding whether or not a claim for such interest is allowed) of any Loan Party under this Agreement, or any Loan Party under any other Loan Document, any Collateral Document or any
other document or instrument executed in connection herewith or therewith, in each case howsoever created, arising or evidenced, whether direct or indirect, absolute or contingent, now or hereafter existing, or due or to become due. 

“OFAC” has the meaning set forth in Section 5.20.1. 

“Other Connection Taxes” means, with respect to the Lender, Taxes imposed as a result of a present or former connection
between the Lender and the jurisdiction imposing such Tax (other than any such connection arising from the Lender having executed, delivered, become a party to, performed its obligations under, received payments under, received or perfected a
security interest under, engaged in any other transaction with respect to the Loan or enforced any Loan Document or sold or assigned an interest in any Loan or Loan Document). 

“Other Taxes” means all present or future stamp, court or documentary, intangible, recording, filing or similar Taxes that
arise from any payment made under, from the execution, delivery, performance, enforcement or registration of, from the receipt or perfection of a security interest under, or otherwise with respect to, any Loan Document, except any such Taxes that
are Other Connection Taxes imposed with respect to an assignment (other than an assignment made pursuant to Section 3.3). 

“Paid in Full” or “Payment in Full” means, with respect to any Obligations, the payment in full in cash and
performance of all such Obligations. 
 “Parent” has the meaning set forth in the Preamble. 

“Patents” means all (i) all patents and certificates of invention, or similar property rights, and applications for any
of the foregoing, of the United States, any other country or any political subdivision thereof, (ii) all reissues, divisions, continuations, continuations-in-part, extensions, renewals, and reexaminations thereof, (iii) all rights
corresponding thereto throughout the world, (iv) all inventions and improvements described therein, (v) all rights to sue for past, present and future infringements thereof, (vi) all licenses, claims, damages, and proceeds of suit
arising therefrom, (vii) all proceeds of the foregoing, including, without limitation, licenses, royalties, and income, and (viii) without duplication, all IP Ancillary Rights in respect of the foregoing. 

“Permitted Lien” means any Lien expressly permitted by Section 7.2. 

“Permitted Refinancing” means any replacement, renewal, refinancing or extension of any existing Debt, in any such case,
permitted by this Agreement (a) that does not exceed the aggregate principal amount (plus accrued interest and any applicable premium and associated fees and expenses) of the Debt being replaced, renewed, refinanced or extended, (b) that
does not have a weighted average life to maturity at the time of such replacement, renewal, refinancing or extension that is less than the weighted average life to maturity of the Debt being replaced, renewed, refinanced or extended, (c) that
does not rank at the time of such replacement, renewal, refinancing or extension senior to the Debt being replaced, renewed, refinanced or extended, (d) in which the primary obligor in respect of, and the Persons (if any) that guarantee, such
Debt (resulting from such replacement, renewal, refinancing or extension) are the primary obligor in 

  
 10 

 
respect of, and Persons (if any) that guaranteed, respectively, the Debt being replaced, renewed, refinanced or extended, and (e) that does not contain terms that are materially less
favorable to any Loan Party, as determined by such Loan Party in the exercise of its reasonable business judgment, than those applicable to the Debt being replaced, renewed, refinanced or extended. 

“Person” means any natural person, corporation, partnership, trust, limited liability company, association, Governmental
Authority or unit, or any other entity, whether acting in an individual, fiduciary or other capacity. 
 “Pfizer” means
Pfizer, Inc., a Delaware corporation, and any successor or assign of Pfizer, Inc. 
 “Prepayment Premium” means at any time
with respect to any Loan being prepaid in whole or in part (including without limitation any prepayment as a result of an acceleration of the Loans hereunder), an amount equal to the product of (x) the principal amount of Loans being prepaid
and (y) the applicable prepayment percentage set forth below opposite the period in which such prepayment is made: 
  

					
	 Period
	  	Prepayment
Percentage	 
	 On or prior to the first anniversary of the Closing Date
	  	 	[**	]% 
	 After the first anniversary of the Closing Date through and including the second anniversary of the Closing Date
	  	 	[**	]% 
	 After the second anniversary of the Closing Date through and including the third anniversary of the Closing Date
	  	 	[**	]% 
	 After the third anniversary of the Closing Date through and including the fourth anniversary of the Closing Date
	  	 	[**	]% 
	 After the fourth anniversary of the Closing Date but prior to the Maturity Date
	  	 	[**	]% 

 “Product” means and includes dalbavancin, any and all future iterations thereof and any other
products developed by any Loan Party. 
 “Qualified Capital Stock” of any person shall mean any Stock of such person that
is not Disqualified Capital Stock. 
 “Required Lenders” means, at any time, lenders hereunder holding Loans representing
more than 50% of the outstanding principal amount of Loans. 
 “Restricted Payment” has the meaning set forth in
Section 7.3. 

  
 11 

 “Security Agreement” means the Security Agreement, dated as of the Closing Date,
executed by Parent and its Subsidiaries in favor of the Agent, and governed by the laws of the State of New York, as amended, restated, supplemented or otherwise modified from time to time in accordance with the terms hereof and thereof. 

“Stock” means all shares of capital stock (whether denominated as common stock or preferred stock), equity interests,
beneficial, partnership or membership interests, joint venture interests, participations or other ownership or profit interests in, or equivalents (regardless of how designated) of, a Person (other than an individual), whether voting or non-voting.

 “Stock Equivalents” means all securities convertible into or exchangeable for Stock or any other Stock Equivalent and
all warrants, options or other rights to purchase, subscribe for or otherwise acquire any Stock or any other Stock Equivalent, whether or not presently convertible, exchangeable or exercisable. For the avoidance of doubt, “Stock
Equivalent” shall not include debt instruments that are convertible into Stock or Stock Equivalents. 
 “Subordinated
Debt” means Debt incurred by the Borrower or any of its Subsidiaries subordinated to all Obligations of the Borrower and its Subsidiaries to the Lender pursuant to a subordination, intercreditor or other similar agreement in form and
substance satisfactory to Agent and the Lender entered into between Agent, the applicable Loan Party or Loan Parties, the other creditor(s) of such Debt and any other Loan Parties as may be required by the Agent, on terms acceptable to Agent and the
Lender. 
 “Subsidiary” means, with respect to any Person, a corporation, partnership, limited liability company or other
entity of which such Person owns, directly or indirectly, such number of outstanding shares of voting Stock or Stock Equivalents as to have more than 50% of the ordinary voting power for the election of directors or other managers of such
corporation, partnership, limited liability company or other entity. Unless the context otherwise requires, each reference to Subsidiaries herein shall be a reference to Subsidiaries of Parent. 

“Subsidiary Guaranty” means each Subsidiary Guaranty executed and delivered by a Subsidiary in favor of the Agent pursuant to
Section 6.7, in form and substance satisfactory to the Agent and the Lender. 
 “Taxes” has the meaning set
forth in Section 3.1(a). 
 “Tax Returns” has the meaning set forth in Section 5.12. 

“Trade Secrets” means all right, title and interest (and all related IP Ancillary Rights) arising under any Applicable Law in
or relating to trade secrets. 
 “Trademark” means all rights, title and interests (and all related IP Ancillary Rights)
arising under any Applicable Law in trademarks, trade names, corporate names, company names, business names, fictitious business names, trade styles, service marks, logos and other source or business identifiers and, in each case, all goodwill
associated therewith, all registrations and recordations thereof and all applications in connection therewith. 

  
 12 

 “Tranche One Commitment” means, as to the Lender, the Lender’s commitment
to provide the Tranche One Loan in the aggregate principal amount of $25,000,000 pursuant to Section 2.1.1(a). 

“Tranche Two Commitment” means, as to the Lender, the Lender’s commitment to provide the Tranche Two Loan in the
aggregate principal amount of $15,000,000 pursuant to Section 2.1.1(b). 
 “Tranche One Loan” means the term loan
from the Lender in a principal amount of $25,000,000 made to the Borrower on the Closing Date pursuant to Section 2.1.1(a). 

“Tranche Two Loan” means the term loan from the Lender in a principal amount of $15,000,000 made to the Borrower pursuant to
Section 2.1.1(b). 
 “Tranche Two Milestone” has the meaning set forth in Section 4.2.2. 

“Tranche Two Milestone Notice” means written notice from the Borrower to the Agent that the Tranche Two Milestone has
occurred. 
 “UCC” means the Uniform Commercial Code as in effect in from time to time in the State of New York. 

“UK Share Charge Documents” means that certain Charge Over Shares, by Durata B.V. in favor of the Agent, over the equity
interests of Durata UK, and any other documents and instruments reasonably requested by the Agent, in each case, in form and substance reasonably acceptable to the Agent. 

“Vicuron” means Vicuron Pharmaceuticals, Inc., a Delaware corporation. 

“Wholly-Owned Subsidiary” means, as to any Subsidiary, all of the Stock and Stock Equivalents of which (except
directors’ qualifying shares) are at the time directly or indirectly owned by Parent and/or another Wholly-Owned Subsidiary of Parent. 

1.2. Interpretation. In the case of this Agreement and each other Loan Document, (a) the meanings of defined terms are equally
applicable to the singular and plural forms of the defined terms; (b) Annex, Exhibit, Schedule and Section references in each Loan Document are to the particular Annex, Exhibit, Schedule and Section of such Loan Document unless otherwise
specified; (c) the term “including” is not limiting and means “including but not limited to”; (d) in the computation of periods of time from a specified date to a later specified date, the word “from” means
“from and including”; the words “to” and “until” each mean “to but excluding”, and the word “through” means “to and including”; (e) unless otherwise expressly provided in such Loan
Document, (i) references to agreements and other contractual instruments shall be deemed to include all subsequent amendments and other modifications thereto, but only to the extent such amendments and other modifications are not prohibited by
the terms of any Loan Document, and (ii) references to any statute or regulation shall be construed as including all statutory and regulatory provisions amending, replacing, supplementing or interpreting such statute or regulation;
(f) this Agreement and the other Loan Documents may use several different limitations, tests or measurements to regulate the same or similar matters, all of which are 

  
 13 

 
cumulative and each shall be performed in accordance with its terms; and (g) this Agreement and the other Loan Documents are the result of negotiations among and have been reviewed by
counsel to the Agent, Parent, the Lender and the other parties hereto and thereto and are the products of all parties; accordingly, this Agreement and the other Loan Documents, in each case, shall not be construed against the Agent or the Lender
merely because of the Agent’s or the Lender’s involvement in their preparation. 
  

	Section 2.	Credit Facilities. 

 2.1. Loans. 

2.1.1. Loans. On the terms and subject to the conditions of this Agreement, the Lender agrees to lend to the Borrower funds in an
aggregate principal amount of up to the Commitment, in installments as follows: 
 (a) on the Closing Date, the entire amount
of its Tranche One Commitment, after which the Tranche One Commitment shall terminate; 
 (b) within five (5) Business
Days after receipt by the Agent from the Borrower of the Tranche Two Milestone Notice, the entire amount of its Tranche Two Commitment, after which the Tranche Two Commitment shall terminate in full; and 

(c) within nine (9) months after the occurrence of the Tranche Two Milestone, at the Borrower’s election, an amount
set forth in Borrower’s written borrowing request (“Borrowing Request”) and not to exceed the Delayed Draw Commitment, after which the Delayed Draw Commitment shall terminate in full; provided that the Borrowing Request must be
received by Lender no later than noon Pacific time three (3) Business Days prior to the date of such proposed borrowing. 
 2.1.2.
General. No portion of the Loans may be re-borrowed once repaid. The proceeds of the Tranche One Loan shall be used to repay and terminate the Existing Obligations in full concurrently with the incurrence of the Tranche One Loan and for
general corporate purposes, in each case, in compliance with the Loan Documents and Applicable Law. The Second Tranche Loan shall be used for general corporate purposes, in compliance with the Loan Documents and Applicable Law. The Delayed Draw Term
Loan shall be used for general corporate purposes, in compliance with the Loan Documents and Applicable Law. 
 2.2. Loan Accounting.

 2.2.1. Recordkeeping. The Agent, on behalf of the Lender, shall record in its records the date and amount of the Loans made by the
Lender, accrued interest and each repayment of principal or interest thereon. The aggregate unpaid principal amount so recorded shall be rebuttably presumptive evidence of the principal amount of the Loans owing and unpaid. The failure to so record
any such amount or any error in so recording any such amount shall not, however, limit or otherwise affect the Obligations of the Borrower hereunder or under any Note to repay the principal amount of the Loans hereunder, together with all interest
accruing thereon. 
 2.2.2. Notes. At the request of the Lender, the Loans shall be evidenced by one or more Notes, with appropriate
insertions, payable to the order of the Lender in a face principal amount equal to the Loans and payable in such amounts and on such dates as are set forth herein. 

  
 14 

 2.3. Interest. 

2.3.1. Interest Rate. 

(a) The Borrower promises to pay interest on the unpaid principal amount of the Tranche One Loan (i) for the period
commencing on the Closing Date and ending on the date of the occurrence of the Tranche Two Milestone, at a rate payable in cash per annum equal to 14.00% and (ii) for the period commencing on the date of the occurrence of the Tranche Two
Milestone until such Loan is Paid in Full, at a rate payable in cash per annum equal to 12.75%. The Borrower promises to pay interest on the unpaid principal amount of (i) the Tranche Two Loan for the period commencing on the borrowing date of
the Tranche Two Loan and (ii) the Delayed Draw Term Loan for the period commencing on the borrowing date of the Delayed Draw Term Loan, in each case until such Loans are Paid in Full, at a rate payable in cash per annum equal to 12.75%. 

(b) The foregoing notwithstanding, (i) at any time an Event of Default exists, the interest rate then applicable to the
Loans shall automatically be increased by two percent (2.00%) per annum (any such increased rate, the “Default Rate”) and (ii) any such increase may thereafter be rescinded by the Lender. In the event that the Obligations
are not Paid in Full as of the Maturity Date, or in the event that the Obligations shall be declared or shall become due and payable pursuant to Section 8.2, the Obligations shall bear interest subsequent thereto at the Default Rate and
such interest shall be payable in cash on demand. In no event shall interest or other amounts payable by the Borrower to the Lender hereunder exceed the maximum rate permitted under Applicable Law, and if any such provision of this Agreement is in
contravention of any such law, (x) any amounts paid hereunder shall be deemed to be and shall be applied against the principal amount of the Obligations to the extent necessary such that the amounts paid hereunder do not exceed the maximum rate
under Applicable Law and (y) such provision shall otherwise be deemed modified as necessary to limit such amounts paid to the maximum rate permitted under Applicable Law. 

2.3.2. Interest Payments. Interest accrued on the Loans during the period from the Closing Date until the Maturity Date shall accrue
and be payable in cash quarterly on each Interest Payment Date, in arrears, and, upon a prepayment of the Loans in accordance with Section 2.4 and at maturity, in each such case, in cash. After maturity and at any time an Event of
Default exists, all accrued interest on the Loans shall be payable in cash on demand at the rates specified in Section 2.3.1. 

2.3.3. Computation of Interest. Interest on the Loans shall be computed on the basis of a 360-day year comprised of twelve 30-day
months. 

  
 15 

 2.4. Amortization; Prepayment. 

2.4.1. Amortization. Commencing on the first Interest Payment Date following the Interest-Only Period, the Borrower shall repay to the
Agent for the account of the Lender on each Interest Payment Date, an amortization payment, plus accrued and unpaid interest, in respect of the outstanding Loans. Such amortization payments shall be equal to the quotient of the product of
(x) the principal amount of the Term Loans as of the first Interest Payment Date following the end of the Interest-Only Period and (y) the percentage applicable to the period in which such amortization payment is made as set forth in the
following schedule: 
  

					
	 Fiscal Quarter Ending
	  	Percentage	 
	 March 31, 2015
	  	 	1.25	% 
	 June 30, 2015
	  	 	1.25	% 
	 September 30, 2015
	  	 	1.25	% 
	 December 31, 2015
	  	 	1.25	% 
	 March 31, 2016
	  	 	5	% 
	 June 30, 2016
	  	 	5	% 
	 September 30, 2016
	  	 	5	% 
	 December 31, 2016
	  	 	5	% 
	 March 31, 2017
	  	 	8.75	% 
	 June 30, 2017
	  	 	8.75	% 
	 September 30, 2017
	  	 	8.75	% 
	 December 31, 2017
	  	 	8.75	% 
	 March 31, 2018
	  	 	10	% 
	 June 30, 2018
	  	 	10	% 
	 September 30, 2018
	  	 	10	% 
	 October 31, 2018
	  	 	10	% 

 If the Delayed Draw Term Loan is funded on or after March 31, 2015, the funded portion of the Delayed Draw Term Loan
shall instead amortize in equal amounts over the remaining amortization payments during such year to achieve an amortization rate for such year of 5%. Each amortization payment hereunder shall be applied pro rata according to the respective
outstanding principal amounts of the Term Loans. 
 2.4.2. Voluntary Prepayment. The Borrowers may, on at least three (3)
Business Days’ written notice to the Agent, not later than 12:00 noon New York City time on such day, prepay the Loans in whole or in part (together with the applicable Prepayment Premium and accrued and unpaid interest to the date of
prepayment on such prepaid amount); provided, however, that each partial prepayment that is not of the entire outstanding amount of any Loan shall be in an aggregate amount that is an integral multiple of $1,000,000. 

  
 16 

 2.5. Payment Upon Maturity. The Loans shall be Paid in Full on the Maturity Date. 

2.6. Making of Payments. All payments on the Loans in accordance with this Agreement, including any payment in respect of the
Prepayment Premium and all payments of fees and expenses, shall be made by the Borrower to the Agent without setoff, recoupment or counterclaim and in immediately available funds, in United States Dollars, by wire transfer to the account of the
Agent specified by the Agent, in any case, not later than 3:00 p.m. New York City time on the date due, and funds received after that hour shall be deemed to have been received by the Agent on the following Business Day. The Agent shall promptly
remit to the Lender all payments received in collected funds by the Agent for the account of such Lender. 
 2.7. Application of Payments
and Proceeds. Each prepayment of the outstanding Loans pursuant to Section 2.4.2 shall be applied pro rata to the remaining principal repayment installments of the Loans. 

2.8. Payment Dates. If any payment of principal of or interest on a Loan, or of any fees, falls due on a day which is not a Business
Day, then such payment shall be made on the Business Day immediately preceding such Interest Payment Date. 
 2.9. Set-off. The
Borrowers agree that the Agent and the Lender have all rights of set-off and bankers’ lien provided by Applicable Law, and in addition thereto, the Borrowers agree that at any time an Event of Default has occurred and is continuing, the Agent
and the Lender may apply to the payment of any Obligations of the Borrowers hereunder, whether or not then due, any and all balances, credits, deposits, accounts or moneys of the Borrowers then or thereafter maintained with the Agent or such Lender.

 2.10. Currency Matters. All amounts payable under this Agreement and the other Loan Documents to the Agent and the Lender shall be
payable in Dollars. 
 2.11. Fees. 

2.11.1. Closing Fee. As consideration for the agreements of the Lender hereunder, the Borrowers agree, jointly and severally, to pay to
the Lender, for its own account, on or prior to the Closing Date, the Closing Fee. 
 2.11.2. Change of Control Fee. Upon the
occurrence of a Change of Control on or before the date of the repayment in full of the Obligations (other than contingent indemnification obligations and other obligations that by the express terms of this Agreement survive the repayment of the
Loans) (on the Maturity Date, by prepayment pursuant to Section 2.4.2 or in the event that the Obligations shall be declared or shall become due and payable pursuant to Section 8.2), the Borrowers agree to pay to the Lender, for its
own account, a change of control fee equal to [**]% of the sum of (i) the full principal amount of the Tranche One Loan, (ii) if borrowed, the full principal amount of the Tranche Two Loan and (iii) if borrowed, the full principal
amount of the Delayed Draw Term Loan which was borrowed by the Borrowers. For the avoidance of doubt, the change of control fee described in the immediately preceding sentence shall be paid in addition to any Prepayment Premium. 

  
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	Section 3.	Yield Protection. 

 3.1. Taxes. 

(a) All payments of principal and interest on the Loan and all other amounts payable under any Loan Document shall be made free
and clear of and without deduction or withholding for any present or future income, excise, stamp, documentary, property or franchise taxes or other taxes, fees, duties, levies, withholdings (including backup withholding) or other charges of any
nature whatsoever imposed by any taxing authority, including any interest, additions to tax or penalties applicable thereto (“Taxes”), except as required by Applicable Law. If any withholding or deduction from any payment to be made
by any Loan Party hereunder is required in respect of any Taxes pursuant to any Applicable Law (as determined in the good faith reasonable discretion of the applicable Loan Party or the Agent), then the applicable Loan Party shall: (i) timely
pay directly to the relevant taxing authority the full amount required to be so withheld or deducted; (ii) within thirty (30) days after the date of any such payment of Taxes, forward to the Agent an official receipt or other documentation
satisfactory to the Agent evidencing such payment to such relevant taxing authority; and (iii) in the case of Indemnified Taxes pay to the Agent for the account of the Lender such additional amount or amounts as is necessary to ensure that the
net amount actually received by the Lender will equal the full amount the Lender would have received had no such withholding or deduction for Indemnified Taxes (including withholdings and deductions applicable to any additional sums payable under
this Section 3.1) been required. 
 (b) The Borrowers shall timely pay to the relevant Governmental Authority in
accordance with Applicable Law, or at the option of the Agent timely reimburse it for the payment of, any Other Taxes. 
 (c)
The Borrowers shall jointly and severally reimburse and indemnify, within 10 days after receipt of written demand therefor (with copy to the Agent), the Agent and the Lender for all Indemnified Taxes (including any additional Indemnified Taxes
imposed by any jurisdiction on amounts payable under this Section 3.1) paid by the Agent or the Lender, or required to be withheld or deducted from a payment to the Agent or the Lender, and any reasonable expenses arising therefrom or
with respect thereto, whether or not such Taxes were correctly or legally asserted. A certificate of the Agent or the Lender (or of the Agent on behalf of the Lender) claiming any compensation under this clause (c), setting forth the amounts to be
paid thereunder and delivered to the Borrowers with a copy to the Agent, shall be conclusive, binding and final for all purposes, absent manifest error. 

(d) On or prior to the date it becomes a party to this Agreement, and from time to time thereafter as required by law or
reasonably requested in 

  
 18 

 
writing by the Borrowers, the Lender (including for purposes of this Section 3.1(d), any assignee of the Lender that becomes a party to this Agreement) shall (but only so long as the
Lender remains lawfully able to do so) provide the Borrowers with such properly completed and executed documents and forms as prescribed by Applicable Law or reasonably requested by a Borrower in order for the Loan Parties to determine if the Lender
is subject to withholding or information reporting requirements and if the Lender is entitled to an exemption from or reduction of withholding Tax, to permit payments to the Lender to be made without withholding or at a reduced rate of withholding
on payments pursuant to this Agreement or any other Loan Document. Notwithstanding anything to the contrary in the preceding sentence, the completion, execution and submission of such documentation shall not be required if in the Lender’s
reasonable judgment such completion, execution or submission would subject such Lender to any material unreimbursed cost or expense, would be disadvantageous to such Lender in any material respect (including any material prejudice to the legal or
commercial position of such Lender) or would require such Lender to disclose information it reasonably deems confidential. The Lender agrees that if any form of certification it previously delivered pursuant to this Section 3.1(d)
expires or becomes obsolete or inaccurate in any respect, it shall promptly update such form or certification. 
 (e) If the
Lender determines, in its sole discretion exercised in good faith, that it has received a refund of any Indemnified Taxes or Other Taxes as to which it has been indemnified by the Borrowers or with respect to which the Borrowers have paid additional
amounts pursuant to this Section, the Lender shall pay to the Borrowers an amount equal to such refund (but only to the extent of indemnity payments made, or additional amounts paid, by the Borrowers under this Section with respect to the taxes
giving rise to such refund), net of all out-of-pocket expenses (including Taxes) incurred by the Lender, and without interest (other than any interest paid by the relevant taxing authority with respect to such refund), provided that the
Borrowers, upon the request of the Lender, agrees to repay the amount paid over to the Borrowers (plus any penalties, interest or other charges imposed by the relevant taxing authority) to the Lender in the event the Lender is required to repay such
refund to such taxing authority. Notwithstanding anything to the contrary in this paragraph (e), in no event will the Lender be required to pay any amount to the Borrowers pursuant to this paragraph (e) the payment of which would place the
Lender in a less favorable net after-Tax position than the Lender would have been in if the Tax subject to indemnification and giving rise to such refund had not been deducted, withheld or otherwise imposed and the indemnification payments or
additional amounts with respect to such Tax had never been paid. This paragraph (e) shall not be construed to require the Lender to make available its tax returns (or any other information relating to its taxes that it deems confidential) to
the Borrowers or any other Person. 
 (f) The provisions of this Section 3.1 shall survive the resignation or
replacement of the Agent, assignment of rights by a Lender, and termination of this Agreement and repayment of all Obligations. 

  
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 3.2. Increased Cost. 

(a) If, after the Closing Date, the adoption or taking effect of, or any change in, any Applicable Law, rule, regulation or
treaty, or any change in the interpretation or administration of any Applicable Law, rule, regulation or treaty by any Governmental Authority, central bank or comparable agency charged with the interpretation or administration thereof, or compliance
by the Lender with any request, rule, guideline or directive (whether or not having the force of law) of any such authority, central bank or comparable agency: (i) shall impose, modify or deem applicable any reserve (including any reserve
imposed by the FRB), special deposit or similar requirement against assets of, deposits with or for the account of, or credit extended by the Lender; (ii) subject the Lender or the Agent to any Taxes (other than Taxes described in clauses
(b) through (d) of the definition of Excluded Taxes, Indemnified Taxes and Connection Income Taxes); or (iii) shall impose on the Lender any other condition affecting its Loan, its Note or its obligation to make the Loan; and the
result of anything described in clauses (i) through (iii) above is to increase the cost to (or to impose a cost on) such Lender of making or maintaining its Loan, or to reduce the amount of any sum received or receivable by such Lender
under this Agreement or under its Note with respect thereto, then, upon demand by such Lender (which demand shall be accompanied by a statement setting forth the basis for such demand and a calculation of the amount thereof in reasonable detail, a
copy of which shall be furnished to the Agent), the Borrowers shall, jointly and severally, pay directly to the Lender such additional amount as will compensate the Lender for such increased cost or such reduction. 

(b) If the Lender shall reasonably determine that any change in, or the adoption or phase-in of, any Applicable Law, rule or
regulation regarding capital adequacy, or any change in the interpretation or administration thereof by any Governmental Authority, central bank or comparable agency charged with the interpretation or administration thereof, or the compliance by the
Lender or any Person controlling the Lender with any request or directive regarding capital adequacy (whether or not having the force of law) of any such authority, central bank or comparable agency, has or would have the effect of reducing the rate
of return on the Lender’s or such controlling Person’s capital as a consequence of such Lender’s Commitments hereunder to a level below that which the Lender or such controlling Person could have achieved but for such change,
adoption, phase-in or compliance (taking into consideration the Lender’s or such controlling Person’s policies with respect to capital adequacy) by an amount deemed by the Lender or such controlling Person to be material, then from time to
time, upon demand by the Lender (which demand shall be accompanied by a statement setting forth the basis for such demand and a calculation of the amount thereof in reasonable detail, a copy of which shall be furnished to the Agent), the Borrowers
shall, jointly and severally, pay to the Lender such additional amount as will compensate the Lender or such controlling Person for such reduction. 

  
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 (c) Notwithstanding anything herein to the contrary, (i) all requests,
rules, guidelines, requirements and directives promulgated by the Bank for International Settlements, the Basel Committee on Banking Supervision (or any successor or similar authority) or by United States or foreign regulatory authorities, in each
case pursuant to Basel III, and (ii) the Dodd-Frank Wall Street Reform and Consumer Protection Act and all requests, rules, guidelines, requirements and directives thereunder or issued in connection therewith or in implementation thereof, shall
in each case be deemed to be a change in Applicable Law, regardless of the date enacted, adopted, issued or implemented. 
 3.3.
Mitigation of Circumstances. The Lender shall promptly notify the Borrowers and the Agent of any event of which it has knowledge which will result in, and will use commercially reasonable efforts available to it (and not, in such
Lender’s sole judgment, otherwise disadvantageous to such Lender) to mitigate or avoid, any obligation by the Borrowers to pay any amount pursuant to Section 3.1 or 3.2; provided, that this Section 3.3
shall not apply to, or operate to prevent, any assignment of the Loan and the rights and obligations of the Lender pursuant to Section 10.13. The Borrowers hereby, jointly and severally, agree to pay all reasonable costs and expenses
incurred by the Lender in connection with this Section 3.3. 
 3.4. Conclusiveness of Statements; Survival.
Determinations and statements of the Lender pursuant to Sections 3.1 or 3.2 shall be conclusive absent demonstrable error provided that the Lender or the Agent provided the Borrowers with written notification of such determinations and
statements. The Lender may use reasonable averaging and attribution methods in determining compensation under Sections 3.1 or 3.2 and the provisions of such Sections shall survive repayment of the Loan, cancellation of the Notes and
termination of this Agreement. 
  

	Section 4.	Conditions Precedent. 

 4.1. Tranche One Loan. The obligation of the Lender to
make the Tranche One Loan on the Closing Date is subject to the following conditions precedent, each of which shall be satisfactory in all respects to the Agent and the Lender: 

4.1.1. Delivery of Loan Documents. Parent and each Borrower shall have delivered the following documents in form and substance
satisfactory to the Agent (and, as applicable, duly executed by all Persons named as parties thereto and dated the Closing Date or an earlier date satisfactory to the Agent): 

(a) Agreement. This Agreement. 

(b) Notes. A Note in respect of the Tranche One Loan. 

(c) Collateral Documents. Except as permitted by Section 6.11, the Security Agreement and all other
Collateral Documents, and all instruments, documents, certificates and agreements executed or delivered pursuant thereto (including pledged equity and limited liability company interests in Parent’s Subsidiaries, if any, with undated
irrevocable transfer powers executed in blank), in each case, executed and delivered by each Loan Party and each other Person named as a party thereto. 

  
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 (d) Financing Statements. Except as permitted by Section 6.11,
properly completed Uniform Commercial Code financing statements and other filings and documents required by law or the Loan Documents to provide the Agent perfected first priority Liens (subject only to Permitted Liens) in the Collateral. 

(e) Lien Searches. Copies of Uniform Commercial Code search reports listing all effective financing statements or
equivalent filings filed against any Loan Party, with copies of such financing statements and filings; and copies of Patent, Trademark, Copyright and Internet Domain Name search reports. 

(f) Authorization Documents. For each Loan Party, such Person’s (i) charter (or similar formation document),
certified as of a recent date by the appropriate Governmental Authority (as applicable) in its jurisdiction of incorporation (or formation), (ii) if this concept exists in the relevant jurisdiction, good standing certificates (or the equivalent
thereof) in its jurisdiction of incorporation (or formation) and in each other jurisdiction where such Loan Party is qualified to conduct business, in each case, dated as of a recent date, (iii) limited liability company agreement, partnership
agreement or bylaws (or equivalent governing document) (as applicable), (iv) resolutions of its board of directors (or similar governing body) approving and authorizing such Person’s execution, delivery and performance of the Loan
Documents to which it is party and the transactions contemplated thereby, and (v) signature and incumbency certificates of its directors and/or officers executing any of the Loan Documents, all certified by its secretary or an assistant
secretary (or similar officer) as being in full force and effect without modification. 
 (g) Opinions of Counsel.
Opinions of counsel for the Parent and each other Loan Party, in form and substance reasonably requested by the Agent. 
 (h)
Insurance. Certificates or other evidence of insurance in effect as required by Section 6.3(b), with endorsements naming the Agent as lenders’ loss payee and/or additional insured, as applicable to be delivered no later than
30 days after the Closing Date. 
 (i) Chattel Paper. Except as permitted by Section 6.11, any tangible
chattel paper (or any other instrument (other than checks received in the ordinary course of business) evidencing any account of any Loan Party) held by any Loan Party, accompanied by instruments of transfer or assignment duly executed in blank, to
be held by the Agent as Collateral pursuant to the Security Agreement. 
 4.1.2. Payment of Fees and Expenses. The Borrowers shall
have paid, on or prior to the Closing Date, (i) all reasonable fees and expenses owing and payable to the Agent and the Lender as of the Closing Date, including the Closing Fee; and (ii) subject to Section 10.3

  
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and without duplication, all reasonable fees, expenses and other amounts payable set forth herein and reasonable costs and expenses incurred by the Agent and the Lender in connection with the
transactions contemplated hereby which are required to be paid by the Borrowers, and shall provide evidence acceptable to the Agent of each of the foregoing. 

4.1.3. Representations and Warranties. Each representation and warranty by each Loan Party contained herein or by each Loan Party in
any other Loan Document to which such Loan Party is a party, shall be true and correct in all material respects (without duplication of any materiality qualifier contained therein) as of the Closing Date. 

4.1.4. No Default. No Default or Event of Default shall have occurred and be continuing. 

4.1.5. No Material Adverse Change. Since December 31, 2012, there has been no event or occurrence that has had or could reasonably
be expected to result in a Material Adverse Effect. 
 4.1.6. Repayment of Existing Obligations. The Loan Parties shall have paid in
full, on or prior to the Closing Date, all Existing Obligations. 
 4.2. Tranche Two Loan. The obligation of the Lender to make the
Tranche Two Loan is subject to the following conditions precedent, each of which shall be satisfactory in all respects to the Agent and the Lender: 

4.2.1. Delivery of Trance Two Milestone Notice. The Borrower shall have delivered the Tranche Two Milestone Notice in respect of the
Tranche Two Milestone. 
 4.2.2. Tranche Two Milestone. On or prior to December 31, 2014, the Borrower shall have received
marketing approval from the United States government of dalbavancin (the “Tranche Two Milestone”). For the avoidance of doubt, if the Tranche Two Milestone has not occurred on or prior to December 31, 2014, the condition set
forth in this Section 4.2.2 shall not be satisfied. 
 4.2.3. Payment of Fees and Expenses. The Borrowers shall have paid, on or
prior to the borrowing date of the Tranche Two Loan, (i) all fees and expenses owing and payable to the Agent and the Lender as of such date and (ii) subject to Section 10.3 and without duplication, all fees, expenses and other
amounts payable set forth herein and costs and expenses incurred by the Agent and the Lender in connection with the transactions contemplated hereby which are required to be paid by the Borrowers on or prior to such borrowing date, and shall provide
evidence acceptable to the Agent of each of the foregoing. 
 4.2.4. Representations and Warranties. Each representation and warranty
by each Loan Party contained herein or by in any other Loan Document to which such Loan Party is a party shall be true and correct in all material respects (without duplication of any materiality qualifier contained therein) as of the proposed
borrowing date of the Tranche Two Loan (except for any representations and warranties that are expressly made as of a prior date, in which case such representations and warranties shall have been true and correct in all material respects on and as
of such earlier date). 

  
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 4.2.5. No Default. No Default or Event of Default shall have occurred and be continuing.

 4.2.6. No Material Adverse Change. Since December 31, 2012, there has been no event or occurrence that has had or could
reasonably be expected to result in a Material Adverse Effect. 
 4.2.7. Note. The Borrowers shall have delivered a Note in respect
of the Tranche Two Loan, duly executed by each Borrower. 
 4.3. Delayed Draw Term Loan. The obligation of the Lender to make the
Delayed Draw Loan is subject to the following conditions precedent, each of which shall be satisfactory in all respects to the Agent and the Lender: 

4.3.1. Delivery of Borrowing Request. The Borrowers shall have delivered a Borrowing Request in respect of the Delayed Draw Term Loan
no later than noon Pacific time at least five (5) Business Days prior to the proposed borrowing date. 
 4.3.2. Tranche Two
Milestone. On or prior to December 31, 2014, the Tranche Two Milestone shall have occurred. For the avoidance of doubt, if the Tranche Two Milestone has not occurred on or prior to December 31, 2014, the condition set forth in this
Section 4.3.2 shall not be satisfied. 
 4.3.3. Payment of Fees and Expenses. The Borrowers shall have paid, on or prior to the
borrowing date of the Delayed Draw Term Loan, (i) all reasonable fees and expenses owing and payable to the Agent and the Lender as of such date and (ii) subject to Section 10.3 and without duplication, all reasonable fees,
expenses and other amounts payable set forth herein and costs and expenses incurred by the Agent and the Lender in connection with the transactions contemplated hereby which are required to be paid by the Borrowers, and shall provide evidence
acceptable to the Agent of each of the foregoing. 
 4.3.4. Representations and Warranties. Each representation and warranty by each
Loan Party contained herein or by in any other Loan Document to which such Loan Party is a party, shall be true and correct in all material respects (without duplication of any materiality qualifier contained therein) as of the proposed borrowing
date of the Delayed Draw Term Loan (except for any representations and warranties that are expressly made as of a prior date, in which case such representations and warranties shall have been true and correct in all material respects on and as of
such earlier date). 
 4.3.5. No Default. No Default or Event of Default shall have occurred and be continuing. 

4.3.6. No Material Adverse Change. Since December 31, 2012, there has been no event or occurrence that has had or could reasonably
be expected to result in a Material Adverse Effect. 
 4.3.7. Note. The Borrowers shall have delivered a Note in respect of the
Delayed Draw Term Loan, duly executed by each Borrower. 

  
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	Section 5.	Representations and Warranties. 

 To induce the Agent and the Lender to enter into this
Agreement and to induce the Lender to advance the Loans hereunder, each Loan Party represents and warrants to the Agent and the Lender as follows: 

5.1. Organization. Each Borrower is a corporation validly existing and in good standing under the laws of the Netherlands; and each
other Loan Party is validly existing and in good standing (as applicable) under the laws of the jurisdiction of its organization; and each Loan Party is duly qualified to do business in each jurisdiction where, because of the nature of its
activities or properties, such qualification is required (except where the failure to be so qualified in such jurisdiction would not reasonably be expected to have a Material Adverse Effect). 

5.2. Authorization; No Conflict. Each Borrower and each other Loan Party is duly authorized to execute and deliver each Loan Document
to which it is a party, each Borrower is duly authorized to borrow monies hereunder, the granting of the security interests pursuant to the Collateral Documents is within the corporate purposes of each Borrower and each other Loan Party thereto, and
each Borrower and each other Loan Party is duly authorized to perform its Obligations under each Loan Document to which it is a party. The execution, delivery and performance by each Borrower of this Agreement and by each Borrower and each Loan
Party of each Loan Document to which it is a party, and the borrowings by the Borrowers hereunder, do not and will not (a) require any consent or approval of any Governmental Authority (other than (i) any consent or approval which has been
obtained and is in full force and effect and (ii) recordings and filings in connection with the Liens granted to the Agent under the Collateral Documents), (b) conflict with (i) any provision of Applicable Law, (ii) the charter,
by-laws, limited liability company agreement, partnership agreement or other organizational documents of any Loan Party or (iii) any material agreement, indenture, instrument or other document, or any judgment, order or decree, which is binding
upon any Loan Party or any of their respective properties or (c) require, or result in, the creation or imposition of any Lien on any asset of either Borrower or any other Loan Party (other than Liens in favor of the Agent created pursuant to
the Collateral Documents). 
 5.3. Validity; Binding Nature. Each of this Agreement and each other Loan Document to which either
Borrower or any other Loan Party is a party is the legal, valid and binding obligation of such Person, enforceable against such Person in accordance with its terms, subject to bankruptcy, insolvency and similar laws affecting the enforceability of
creditors’ rights generally and to general principles of equity. 

  
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 5.4. Financial Condition. The unaudited consolidated financial statements of Parent and
its Subsidiaries (presented on a consolidated basis) as at June 30, 2013, and the audited consolidated financial statements of Parent and its Subsidiaries (presented on a consolidated basis) as at December 31, 2012, have been prepared in
accordance with GAAP and present fairly the consolidated financial condition of such Persons as at such dates and the results of their operations for the periods then ended (except for the absence of footnotes and subject to year-end adjustments).
As of the Closing Date, Parent and its Subsidiaries have no material liabilities other than as set forth on the foregoing financial statements and other than reimbursement obligations with respect to letters of credit. 

5.5. No Material Adverse Change. Since December 31, 2012, there has been no event or occurrence that has or could reasonably be
expected to result in a Material Adverse Effect. 
 5.6. Litigation. No litigation (including derivative actions), arbitration
proceeding or governmental investigation or proceeding is pending, or threatened in writing, against any Loan Party or any of their respective properties which (i) purport to affect or pertain to this Agreement, any other Loan Document or any
of the transactions contemplated hereby or (ii) that could reasonably be expected to have, either individually or in the aggregate, a Material Adverse Effect. No injunction, writ, temporary restraining order or any order of any nature has been
issued by any court or other Governmental Authority purporting to enjoin or restrain the execution, delivery or performance of this Agreement, any other Loan Document, or directing that the transactions provided for herein not be consummated as
herein provided. As of the Closing Date, no Loan Party is the subject of an audit or, to each Loan Party’s knowledge, any review or investigation by any Governmental Authority (excluding the IRS and other taxing authorities) concerning the
violation or possible violation of any requirement of law. 
 5.7. Ownership of Properties; Liens. There are no Liens on the
Collateral other than those granted in favor of the Agent to secure the Obligations and Permitted Liens. Each Borrower and each other Loan Party owns good and, in the case of real property, marketable, title to all of its properties and assets, real
and personal, tangible and intangible, of any nature whatsoever (including patents, trademarks, trade names, service marks and copyrights), free and clear of all Liens, charges and claims (including infringement claims with respect to Intellectual
Property) other than Permitted Liens. 
 5.8. Capitalization; Subsidiaries. 

(a) Equity Interests. Except as set forth in Section 5.8 of the Disclosure Letter, as of the Closing Date,
Parent has no Subsidiaries and does not hold any Capital Stock of any other Person. All Stock and Stock Equivalents of each Loan Party are duly and validly issued and, in the case of each entity that is a corporation, are fully paid and
non-assessable, and, other than the Stock and Stock Equivalents of Parent, are owned by Parent, directly or indirectly through Wholly-Owned Subsidiaries. Each Loan Party is the record and beneficial owner of, and has good and marketable title to,
the Stock and Stock Equivalents pledged by it to the Agent under the Collateral Documents, free of any and all Liens, rights or claims of other persons, except the security interest created by the Collateral Documents, and there are no outstanding
warrants, options or other 

  
 26 

 
rights to purchase, or shareholder, voting trust or similar agreements outstanding with respect to, or property that is convertible into, or that requires the issuance or sale of, any such Stock
and Stock Equivalents. As of the Closing Date, no Loan Party is engaged in any joint venture with any other Person. 
 (b)
No Consent of Third Parties Required. Other than with respect to consents required by the Dutch Security Documents, no consent of any Person including any other general or limited partner, any other member of a limited liability company, any
other shareholder or any other trust beneficiary is necessary for the creation, perfection or first priority status of the security interest of the Agent in any Stock and Stock Equivalents pledged to the Agent for the benefit of the Lender under the
Collateral Documents or the exercise by the Agent of the voting or other rights provided for in the Collateral Documents or the exercise of remedies in respect thereof. 

5.9. Pension Plans. No Loan Parties have any liability under ERISA and no Loan Party sponsors any “pension plan” or has any
liability subject to Title IV of ERISA. 
 5.10. Compliance with Law; Investment Company Act; Other Regulated Entities. Each Borrower
and each other Loan Party possesses all necessary authorizations, permits, licenses and approvals from all Governmental Authorities in order to conduct their respective businesses as presently conducted, except where the failure to do so could not
reasonably be expected to result in a Material Adverse Effect. All business and operations of each Borrower and each other Loan Party complies with all applicable federal, state and local laws and regulations, except where the failure so to comply
could not reasonably be expected to result in a Material Adverse Effect. Neither Borrower nor any other Loan Party is an “investment company” or a company “controlled” by an “investment company” or a
“subsidiary” of an “investment company”, within the meaning of the Investment Company Act of 1940. No Loan Party nor any Subsidiary of any Loan Party is subject to regulation under any Federal or state statute, rule or regulation
limiting its ability to incur Debt, pledge its assets or perform its Obligations under the Loan Documents. 
 5.11. Margin Stock.
Neither Borrower nor any Loan Party is engaged principally, or as one of its important activities, in the business of extending credit for the purpose of purchasing or carrying Margin Stock. No portion of the Obligations is secured directly or
indirectly by Margin Stock. 
 5.12. Taxes. Each Borrower and each other Loan Party has filed all federal, state, provincial, local
and foreign income, sales, goods and services, harmonized sales and franchise and other material tax returns, reports and statements (collectively, the “Tax Returns”) with the appropriate Governmental Authorities in all
jurisdictions in which such Tax Returns are or were required to be filed. All such Tax Returns are true, correct and complete in all material respects. All material Taxes reflected therein or otherwise due and payable have been paid prior to the
date on which any liability may be added thereto for non-payment thereof, except for those contested in good faith by appropriate proceedings diligently conducted and for which adequate reserves are maintained on the books of the appropriate Loan
Party, as applicable. As of the Closing Date, no Tax Return is under audit or examination by any Governmental Authority and no notice of such an audit or examination or any assertion of any claim for Taxes has been given

  
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or made by any Governmental Authority. Proper and accurate amounts have been withheld by each Loan Party, as applicable, from their respective employees for all periods in material compliance
with the tax, social security and unemployment withholding provisions of Applicable Law and such withholdings have been timely paid to the respective Governmental Authorities in accordance with Applicable Law. As of the Closing Date, no Loan Party
has been a member of an affiliated, combined or unitary group, other than a group of which a Loan Party is the common parent, or has liability for Taxes of any other person (other than customary indemnification obligations contained in commercial
agreements not principally related to Taxes (including credit or other commercial lending agreements, stock or asset purchase agreements, or arrangements with landlords, lessors, customers and vendors). 

5.13. Solvency. Both immediately before and after giving effect to (a) the Loan made on or prior to the date this representation
and warranty is made or remade, (b) the disbursement of proceeds of such Loan, and (c) the payment and accrual of all transaction costs in connection with the foregoing, with respect to Parent and each other Loan Party, on a consolidated
basis, (i) the fair value of the assets of Parent and each other Loan Party, on a consolidated basis, is greater than the amount of the liabilities (including disputed, contingent and unliquidated liabilities) of Parent and each other Loan
Party, on a consolidated basis, as such value is established and liabilities evaluated, (ii) the present fair saleable value of the assets of Parent and each other Loan Party, on a consolidated basis, is not less than the amount that will be
required to pay the probable liability on the debts of Parent and each other Loan Party, on a consolidated basis, as they become absolute and matured, (iii) Parent and each other Loan Party, on a consolidated basis, are able to realize upon
their assets and pay their debts and other liabilities (including disputed, contingent and unliquidated liabilities) as they mature in the normal course of business, (iv) neither Parent nor any other Loan Party intends to incur debts or
liabilities beyond its ability to pay as such debts and liabilities mature, (v) neither Parent nor any other Loan Party is engaged in business or a transaction, and is not about to engage in business or a transaction, for which its property
would constitute unreasonably small capital, and (vi) each of Parent and its Subsidiaries are “solvent” within the meaning given that term and similar terms under applicable laws relating to bankruptcy, insolvency and fraudulent
transfers and conveyances. 
 5.14. Environmental Matters. The on-going operations of the Borrower and each other Loan Party comply
in all respects with all Environmental Laws, except such non-compliance which could not (if enforced in accordance with Applicable Law) reasonably be expected to result in a Material Adverse Effect. Each Borrower and each other Loan Party have
obtained, and maintained in good standing, all licenses, permits, authorizations and registrations required under any Environmental Law and necessary for their respective ordinary course operations, and each Borrower and each other Loan Party are in
compliance with all material terms and conditions thereof, except in each case where the failure to do so could not reasonably be expected to result in a Material Adverse Effect. None of the Borrowers, any other Loan Party or any of their respective
properties or operations is subject to any outstanding written order from or agreement with any federal, state or local Governmental Authority, nor subject to any judicial or docketed administrative proceeding, nor subject to any indemnification
agreement or other contractual obligation in each case that could reasonably be expected to have a Material Adverse Effect, respecting any Environmental Law, Environmental Claim or Hazardous Substance. There are no Hazardous Substances or other
environmental conditions or circumstances existing with respect to any property, or arising from operations prior to the Closing Date, of either 

  
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Borrower or any other Loan Party that could reasonably be expected to result in a Material Adverse Effect. Neither Borrower nor any other Loan Party has any underground or above ground storage
tanks that are not properly registered or permitted under applicable Environmental Laws or that are leaking or disposing of Hazardous Substances. 

5.15. Insurance. Each Borrower and each other Loan Party and their respective properties are insured with financially sound and
reputable insurance companies which are not Affiliates of Parent, in such amounts, with such deductibles and covering such risks as are customarily carried by companies engaged in similar businesses and owning similar properties in localities where
each Borrower or such other Loan Party operates. A true and complete listing of such insurance as of the Closing Date, including issuers and coverages, is set forth in Section 5.15 of the Disclosure Letter. 

5.16. Information. All information heretofore or contemporaneously herewith furnished in writing by either Borrower or any other Loan
Party to the Agent or the Lender for purposes of or in connection with this Agreement and the transactions contemplated hereby is, and all written information hereafter furnished by or on behalf of either Borrower or any Loan Party to the Agent or
the Lender pursuant hereto or in connection herewith will be, taken together with all such other information, true and accurate in every material respect on the date as of which such information is dated or certified, and none of such information is
or will be incomplete, taken together with all such other information, by omitting to state any material fact necessary to make such information not misleading in light of the circumstances under which made (it being recognized by the Agent and the
Lender that any projections and forecasts provided by Parent are based on good faith estimates and assumptions believed by Parent to be reasonable as of the date of the applicable projections or assumptions and that actual results during the period
or periods covered by any such projections and forecasts may differ from projected or forecasted results). 
 5.17. Intellectual
Property. Each Loan Party owns, or is licensed or otherwise has the right to use, all Intellectual Property necessary to conduct its business as currently conducted except for such Intellectual Property the failure of which to own or have a
license or other right to use would not reasonably be expected to have, either individually or in the aggregate, a Material Adverse Effect. To the knowledge of each Loan Party, (a) the conduct and operations of the businesses of each Loan Party
do not, and the anticipated products and Intellectual Property applications of the Loan Parties will not, infringe upon, misappropriate, dilute or violate any Intellectual Property owned by any other Person and (b) no other Person has contested
any right, title or interest of any Loan Party in any Intellectual Property or any anticipated products and applications derived or expected to be derived therefrom, other than, in each case, as cannot reasonably be expected to have, individually or
in the aggregate, a Material Adverse Effect. The Intellectual Property of the Loan Parties is sufficient, and conveys adequate rights, title and interests, for each Borrower and other Loan Parties to develop and commercialize its anticipated
products and Intellectual Property applications. 
 5.18. Labor Matters. Neither Borrower nor any other Loan Party is subject to any
labor or collective bargaining agreement. There are no existing or threatened strikes, lockouts or other labor disputes involving either Borrower or any other Loan Party that individually or in the aggregate could reasonably be expected to have a
Material Adverse Effect. Hours worked by 

  
 29 

 
and payment made to employees of either Borrower and the other Loan Parties are not in violation of the Fair Labor Standards Act or any other Applicable Law, rule or regulation dealing with such
matters. 
 5.19. No Default. No Loan Party is in default under or with respect to any contractual obligation in any respect which,
individually or together with all such defaults, would reasonably be expected to have a Material Adverse Effect. 
 5.20. Foreign Assets
Control Regulations and Anti-Money Laundering. 
 5.20.1. OFAC. Each Loan Party is and will remain in compliance in all material
respects with all U.S. economic sanctions laws, Executive Orders and implementing regulations as promulgated by the U.S. Treasury Department’s Office of Foreign Assets Control (“OFAC”) and all applicable anti-money laundering
and counter-terrorism financing provisions of the Bank Secrecy Act and all regulations issued pursuant to any of the foregoing. No Loan Party (i) is a Person designated by the U.S. government on the list of the Specially Designated Nationals
and Blocked Persons (the “SDN List”) with which a U.S. Person cannot deal with or otherwise engage in business transactions, (ii) is a Person who is otherwise the target of U.S. economic sanctions laws such that a U.S. Person
cannot deal or otherwise engage in business transactions with such Person or (iii) is controlled by (including without limitation by virtue of such person being a director or owning voting shares or interests), or acts, directly or indirectly,
for or on behalf of, any person or entity on the SDN List, a Terrorist List or a foreign government that is the target of U.S. economic sanctions prohibitions such that the entry into, or performance under, this Agreement or any other Loan Document
would be prohibited under U.S. law. 
 5.20.2. Patriot Act. The Loan Parties are in compliance in all material respects with
(a) the Trading with the Enemy Act, and each of the foreign assets control regulations of the United States Treasury Department (31 CFR, Subtitle B Chapter V, as amended) and any other enabling legislation or executive order relating thereto
and (b) the Patriot Act. No part of the proceeds of any Loan will be used directly or indirectly for any payments to any government official or employee, political party, official of a political party, candidate for political office, or anyone
else acting in an official capacity, in order to obtain, retain or direct business or obtain any improper advantage, in violation of the United States Foreign Corrupt Practices Act of 1977. 

5.21. [Reserved]. 
 5.22.
Internal Controls. Parent acknowledges that its management is responsible for establishing and maintaining effective internal control over financial reporting and assessing the effectiveness of internal control over financial reporting.
Parent has performed an evaluation and made an assessment of the effectiveness of the Company’s internal control over financial reporting as of December 31, 2012. Based on Parent’s assessment, Parent has concluded that it maintained
effective internal control over financial reporting as of December 31, 2012. 

  
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	Section 6.	Affirmative Covenants. 

 Until all Obligations (other than contingent indemnification
obligations to the extent no claim giving rise thereto has been asserted and other obligations that by the express terms of this Agreement survive the repayment of the Loans) are Paid in Full, each Loan Party agrees that, unless at any time the
Lender shall otherwise expressly consent in writing, it will: 
 6.1. Information. Furnish to the Agent and the Lender: 

6.1.1. Annual Report. Promptly when available and in any event within 90 days of the end of each Fiscal Year of Parent beginning with
the Fiscal Year ending December 31, 2013, the audited consolidated financial statements of Parent and its Subsidiaries as at the end of such Fiscal Year prepared on a basis consistent with GAAP. 

6.1.2. Quarterly Reports. Commencing with respect to the first Fiscal Quarter of 2014, promptly when available and in any event within
45 days of the end of such Fiscal Quarter and each subsequent Fiscal Quarter (except in each case for the fourth Fiscal Quarter of any Fiscal Year of the Parent), a consolidated balance sheet of Parent and its Subsidiaries as of the end of such
fiscal quarter, together with consolidated statements of income and cash flows for such period prepared on a basis consistent with GAAP, and a management discussion and analysis relating to such information in reasonable detail, together with a
comparison with the corresponding period of the previous Fiscal Year, certified by the chief financial officer of Parent pursuant to a Compliance Certificate. 

6.1.3. [Reserved.] 

6.1.4. Compliance Certificate. Contemporaneously with the furnishing of the financial statements required pursuant to Sections
6.1.1 and 6.1.2, a duly completed Compliance Certificate signed by the chief financial officer of Parent to the effect that such officer has not become aware of any Event of Default or Default that has occurred and is continuing or, if
there is any such Event of Default, describing it and the steps, if any, being taken to cure it, and providing such other information as required thereby. 

6.1.5. Notice of Default; Litigation; ERISA Matters. Promptly upon becoming aware of any of the following, written notice describing
the same and the steps being taken by the Borrowers or the applicable Loan Party affected thereby with respect thereto: 

(a) the occurrence of an Event of Default or a Default; 

(b) any litigation, arbitration or governmental investigation or proceeding not previously disclosed by the Borrowers to the
Lender which has been instituted or is threatened in writing against a Borrower or any other Loan Party, or to which any of the properties of any thereof is subject, which could reasonably be expected to have a Material Adverse Effect; 

(c) any cancellation or material change in coverage in any insurance maintained by a Borrower or any other Loan Party; or 

(d) any other event (including (i) any violation of any Environmental Law or the assertion of any Environmental Claim,
(ii) the enactment or effectiveness of any law, rule or regulation, (iii) any violation or noncompliance with any law or (iv) any breach or non-performance of, or any default under, any contractual obligation of any Loan Party) which
could reasonably be expected to have a Material Adverse Effect. 

  
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 6.1.6. [Reserved.] 

6.1.7. Budgets. As soon as practicable, and in any event not later than 31 days after the commencement of each Fiscal Year, a
consolidated budget of Parent and its Subsidiaries for such Fiscal Year (including quarterly operating and cash flow budgets), accompanied by a certificate of the chief financial officer of Parent to the effect that (a) such budget was prepared
by Parent, in good faith, (b) Parent has a reasonable basis for the assumptions contained in such budget and (c) such budget has been prepared in accordance with such assumptions. 

6.1.8. Other Information. Promptly from time to time, such other information concerning either Borrower and any other Loan Party as the
Lender or the Agent may reasonably request. 
 6.2. Books; Records; Inspections. Keep, and cause each Loan Party to keep, its books
and records in accordance with sound business practices sufficient to allow the preparation of financial statements in accordance with GAAP; permit, and cause each Loan Party to permit (but no more than once per year unless an Event of Default has
occurred and is continuing), the Agent or any representative of the Agent to inspect, at any reasonable time and with reasonable notice (or at any time without notice if an Event of Default exists), the properties and operations of such Loan Party;
and permit (but no more than once per year unless an Event of Default has occurred and is continuing), and cause each Loan Party to permit, at any reasonable time and with reasonable notice (or at any time without notice if an Event of Default
exists), the Agent or any representative of the Agent to visit any or all of its offices, to discuss its financial matters with its directors or officers and its independent auditors, if any (and Parent hereby authorizes such independent auditors,
if any, to discuss such financial matters with the Lender or the Agent or any representative thereof), and to examine (and, at the expense of the Borrowers or the applicable Loan Party, photocopy extracts from) any of its books or other records; and
permit, and cause each Loan Party to permit, the Agent and its representatives to inspect (but no more than once per year unless an Event of Default has occurred and is continuing), at any reasonable time and with reasonable notice (or at any time
without notice if an Event of Default exists), the Collateral and other tangible assets of such Loan Party, to perform appraisals of the equipment of such Loan Party, and to inspect, audit, check and make copies of and extracts from the books,
records, computer data, computer programs, journals, orders, receipts, correspondence and other data relating to any Collateral, for purposes of or otherwise in connection with conducting a review, audit or appraisal of such books and records. 

6.3. Maintenance of Property; Insurance; Intellectual Property. 

(a) Keep, and cause each other Loan Party to keep, all property useful and necessary in the business of either Borrower or such
other Loan Party (other than Intellectual Property) in good working order and condition, ordinary wear and tear excepted. 

  
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 (b) Maintain, and cause each other Loan Party to maintain, with responsible
insurance companies, such insurance coverage as shall be required by all laws, governmental regulations and court decrees and orders applicable to it and such other insurance, to such extent and against such hazards and liabilities, as is
customarily maintained by similarly situated companies. Upon request of the Agent, Parent shall furnish to the Agent a certificate setting forth in reasonable detail the nature and extent of all insurance maintained by Parent and each other Loan
Party. Parent shall cause each issuer of an insurance policy to provide the Agent with an endorsement (i) showing the Agent as a loss payee with respect to each policy of property or casualty insurance and naming the Agent as an additional
insured with respect to each policy of liability insurance and (ii) providing that 30 days’ notice will be given to the Agent prior to any cancellation of such policy (except 10 days’ notice of cancellation for non-payment). Upon
request of the Agent, Parent will use commercially reasonable efforts to execute and deliver to the Agent a collateral assignment, in form and substance reasonably satisfactory to the Agent, of any business interruption insurance policy maintained
by the Loan Parties. 
 (c) Unless Parent provides the Agent with evidence of the continuing insurance coverage required by
this Agreement, after request by the Agent, the Agent may purchase insurance (to the extent of such insurance coverage as shall be required by clause (b) above) at Parent’s expense to protect the Agent’s and the Lender’s
interests in the Collateral. This insurance may, but need not, protect the Borrowers’ and each other Loan Party’s interests. The coverage that the Agent purchases may, but need not, pay any claim that is made against the Borrowers or any
other Loan Party in connection with the Collateral. Parent may later cancel any insurance purchased by the Agent, but only after providing the Agent with evidence that Parent has obtained the insurance coverage required by this Agreement. If the
Agent purchases insurance for the Collateral, as set forth above, Parent will be responsible for the costs of that insurance, including interest and any other charges that may be imposed with the placement of the insurance, until the effective date
of the cancellation or expiration of the insurance and the costs of the insurance may be added to the principal amount of the Loan owing hereunder. 

(d) Each Loan Party and each of its Subsidiaries shall: (i) use commercially reasonable efforts to protect, defend and
maintain the validity and enforceability of its Intellectual Property that is material to its business; (ii) promptly advise the Agent in writing of material infringement of which it is aware by a third party of its Intellectual Property; and
(iii) not allow any Intellectual Property material to its business to be abandoned, forfeited or dedicated to the public without the Agent’s prior written consent; provided, that the Agent’s consent shall not be required if
such Loan Party’s decision to abandon the prosecution of or otherwise not maintain such Intellectual Property is made for strategic business reasons and such Intellectual Property is not registered in the United States, the United Kingdom,
France, Spain, Italy or Germany. 

  
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 6.4. Compliance with Laws and Contractual Obligations; Payment of Taxes and Liabilities.
(a) Comply, and cause each other Loan Party to comply, with all Applicable Laws, rules, regulations, decrees, orders, judgments, licenses and permits and all indentures, agreements and other instruments binding upon it or its property, except
where failure to comply could not reasonably be expected to have a Material Adverse Effect; (b) without limiting clause (a) above, ensure, and cause each other Loan Party to ensure, that no Loan Party is or shall be (i) listed on the
Specially Designated Nationals and Blocked Person List maintained by OFAC, Department of the Treasury, and/or any other similar lists maintained by OFAC pursuant to any authorizing statute, Executive Order or regulation or (ii) a person
designated under Section 1(b), (c) or (d) of Executive Order 13224, any related enabling legislation or any other similar Executive Orders; (c) without limiting clause (a) above, comply and cause each
other Loan Party to comply, with all applicable Bank Secrecy Act and anti-money laundering laws and regulations; and (d) timely prepare and file all material Tax Returns required to be filed by Applicable Law and pay, and cause each other Loan
Party to pay, prior to delinquency, all material Taxes against it or any of its property, as well as claims of any kind which, if unpaid, could become a Lien on any of its property; provided that the foregoing shall not require the Borrowers
or any other Loan Party to pay any such Tax or charge so long as it shall promptly contest the validity thereof in good faith by appropriate proceedings and shall set aside on its books adequate reserves with respect thereto in accordance with GAAP.

 6.5. Maintenance of Existence. Maintain and preserve, and (subject to Section 7.4) cause each other Loan Party to
maintain and preserve, (a) its existence and good standing (as applicable) in the jurisdiction of its organization and (b) its qualification to do business and good standing (as applicable) in each jurisdiction where the nature of its
business makes such qualification necessary, other than in the case of this clause (b) any such jurisdiction where the failure to be qualified or in good standing could not reasonably be expected to have a Material Adverse Effect. 

6.6. Environmental Matters. If any release or disposal of Hazardous Substances shall occur or shall have occurred on or from any real
property of either Borrower or any other Loan Party, cause, or direct the applicable Loan Party to cause, the prompt containment and removal of such Hazardous Substances and the remediation of such real property or other assets as is necessary to
comply in all material respects with all Environmental Laws and to preserve the value of such real property or other assets. Without limiting the generality of the foregoing, each Borrower shall, and shall cause each other Loan Party to, comply with
each Applicable Law and judicial or administrative order requiring the performance at any real property by such Borrower or any other Loan Party of activities in response to the release or threatened release of a Hazardous Substance. If any
violation of any Environmental Law shall occur or shall have occurred at any real property of either Borrower or any other Loan Party or otherwise in connection with their operations, cause, or direct the applicable Loan Party to cause, the prompt
correction of such violation. 
 6.7. Further Assurances. 

(a) General Assurances. Promptly upon request by the Agent, the Loan Parties shall (and, subject to the limitations
hereinafter set forth, shall cause each of their Subsidiaries to) take such additional actions as the Agent may 

  
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reasonably require from time to time in order (i) to subject to the Liens created by any of the Collateral Documents any of the properties, rights or interests, whether now owned or
hereafter acquired, covered or intended to be covered by any of the Collateral Documents, (ii) to perfect and maintain the validity, effectiveness and priority of any of the Collateral Documents and the Liens intended to be created thereby, and
(iii) to better assure, convey, grant, assign, transfer, preserve, protect and confirm to the Agent and the Lender the rights granted or now or hereafter intended to be granted to the Agent and the Lender under any Loan Document or under any
other document executed in connection therewith. Notwithstanding the foregoing, no additional actions shall be required with respect to Intellectual Property other than Intellectual Property registered with any United States Governmental Authority
or with any Governmental Authority in the United Kingdom, France, Spain, Italy and Germany. 
 (b) Subsidiaries.
Without limiting the generality of the foregoing and except as otherwise approved in writing by the Lender, the Loan Parties shall cause each of their Subsidiaries, including any such Subsidiary formed or acquired after the Closing Date, to guaranty
the Obligations and cause each such Subsidiary to grant to the Agent, for the benefit of the Agent and the Lender, a security interest in, subject to the limitations set forth herein or set forth in the Security Agreement, all of such
Subsidiary’s property to secure such guaranty, in each case pursuant to the execution and delivery of a Subsidiary Guaranty and a joinder to the Security Agreement and such other documents as may be reasonably requested, each in form and
substance reasonably satisfactory to the Agent; provided, however that Durata UK shall not be required to execute and delivery a Subsidiary Guaranty. Furthermore and except as otherwise approved in writing by the Lender, each Borrower shall, and
shall cause each of its Subsidiaries to, pledge all of the Stock and Stock Equivalents of each of its Subsidiaries to the Agent for the benefit of the Agent and the Lender, to secure the Obligations, in each case pursuant to documents in form and
substance reasonably satisfactory to the Agent. In connection with each pledge of Capital Stock that is certificated, Parent and each Subsidiary shall deliver, or cause to be delivered, to the Agent, irrevocable proxies and stock powers and/or
assignments, as applicable, duly executed in blank, in each case pursuant to documents in form and substance reasonably satisfactory to the Agent. 

(c) Collateral Access Agreements. Parent and each Loan Party shall be under an ongoing obligation to use commercially
reasonable efforts to obtain a Collateral Access Agreement from the lessor of each leased property and bailee in possession of any Collateral (other than Excluded Inventory) with a book value in excess of $250,000 with respect to each location
within the United States (except in respect of the Hospira Facility occupied as of the Closing Date) where such Collateral is stored or located, which Collateral Access Agreement shall be in form and substance reasonably satisfactory to the Agent.

 (d) Intellectual Property. In the event that any Loan Party shall acquire any material registered Patent, Copyright
or Trademark or register any 

  
 35 

 
material Patent, Copyright, Trademark, or other Intellectual Property with any United States Governmental Authority or with any Governmental Authority in the United Kingdom, France, Spain, Italy
and Germany, or register any application for, or license in respect of, any of the foregoing with such Governmental Authority, Parent shall notify the Agent thereof within five (5) Business Days after the last day of the fiscal quarter in which
(or, with respect to any Copyright, within five (5) Business Days after) such filing occurs and shall promptly thereafter execute and deliver to the Agent, for the benefit of the Lender, such Intellectual Property Security Agreements, in form
and substance substantially as set forth in Exhibit C hereto with respect to Intellectual Property in the United States and otherwise in form and substance reasonably acceptable to the Agent with respect to Intellectual Property outside of
the United States in order to secure and perfect the security interest in respect of such Intellectual Property in the United States, the United Kingdom, France, Spain, Italy and Germany. In no event shall any such Intellectual Property Security
Agreements contain covenants, representations or defaults that are inconsistent with, or more detailed than, the provisions in Section 6.3(d) of this Loan Agreement. 

6.8. Internal Controls. The internal controls of Parent and each other Loan Party over financial reporting will comply with Applicable
Law in all material respects. 
 6.9. Tranche Two Milestone Notice. As promptly as practicable and in any event within five
(5) Business Days after the occurrence of the Tranche Two Milestone, the Borrowers shall deliver to Agent (i) the Tranche Two Milestone Notice and (ii) a certificate of the Borrowers signed by the chief financial officer of the
Borrowers certifying as to the occurrence of the Tranche Two Milestone. 
 6.10. Conference Calls. After delivery of the financial
statements pursuant to Section 6.1.1 and 6.1.2, at the request of the Agent, cause its chief financial officer or its vice president of finance and accounting to participate in conference calls with the Agent and the Lender to
discuss, among other things, the financial condition of the Loan Parties and any financial or earnings reports. 
 6.11. Post-Closing
Obligations. Notwithstanding any provision herein or in any other Loan Document to the contrary, to the extent not actually delivered on or prior to the Closing Date, the Borrowers shall, and shall cause each applicable to Loan Party: 

(a) no later than 30 days after the Closing Date, the Borrowers shall have delivered endorsements naming the Agent as
lenders’ loss payee and/or additional insured, as applicable, with respect to the insurance in effect as required by Section 6.3(b); 

(b) no later than 60 days after the Closing Date (or such later date as the Agent may agree) the Borrowers shall have
delivered fully executed Dutch Security Documents and an opinion of counsel to the Borrowers in form and substance reasonably satisfactory to the Agent; 

  
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 (c) except as permitted by Section 7.12 with respect to certain
accounts not subject to the requirement to deliver control agreements, no later than 10 Business Days after the Closing Date (or such later date as the Agent may agree) deliver to the Agent full executed account control agreements for each deposit
account and securities account maintained by any Loan Party organized in the United States, in form and substance reasonably satisfactory to Agent; 

(d) within 10 Business Days after the Closing Date, the Borrowers shall have delivered the UK Share Charge Documents, stock
transfer forms and certified copies of the share register to the Agent; 
 (e) within 10 Business Days after the Closing
Date, the Borrowers shall have delivered the stock certificates stock certificates of Vicuron and Durata UK to the Agent; 

(f) within 90 days after the Closing Date, each of the Borrowers shall have either (i) transferred each of its primary
operating accounts to an account located in the United States and in respect of which it has delivered a Control Agreement to Agent or (ii) notified bank account depositaries holding the Borrowers’ primary operating accounts in the
Netherlands of the Liens of the Lenders and Agent and take such actions under Dutch law as would be reasonably required to give the Lenders and the Agent and effective Lien on the Borrowers’ primary operating accounts in the Netherlands;
provided, however, that this Section 6.11(f) shall not apply to any primary operating account holding an average balance of less than $500,000; 

(g) no later than 10 days after the Closing Date, each foreign Loan Party shall finalize its appointment of CT Corporation
System as such Loan Party’s agent where notices and demands to or upon such Loan Party in respect of this Agreement, the Security Agreement, the Intellectual Property Security Agreements (as defined in the Security Agreement) or the Subsidiary
Guaranties may be served (without prejudice to the right of the Agent or the Lender to serve process in any other manner permitted by law); and 

(h) no later than 10 days after the Closing Date, the Borrowers shall have delivered the $75,000,000 Promissory Note from
Durata C.V. to Parent dated June 8, 2012 from Oxford Finance, LLC to the Agent. 
  

	Section 7.	Negative Covenants. 

 Until the Obligations are Paid in Full, each Loan Party agrees that,
unless at any time the Lender shall otherwise expressly consent in writing (such consent to be withheld in the Lender’s sole discretion), it will: 

7.1. Debt. Not, and not suffer or permit any Loan Party or any other Subsidiary, to, create, incur, assume or suffer to exist any Debt,
except for the following: 
 (a) Obligations under this Agreement and the other Loan Documents; 

  
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 (b) Debt in respect of Capital Leases and purchase money Debt, in each case
incurred for the purpose of financing all or any part of the cost of acquiring, repair, construction or improvement of fixed or capital assets; provided that the aggregate principal amount of all such Debt at any time outstanding shall not
exceed $250,000; 
 (c) Debt of Parent to any Loan Party that is a Wholly-Owned Subsidiary of Parent or Debt of any Loan
Party that is a Wholly-Owned Subsidiary of Parent to Parent or another Loan Party that is a Wholly-Owned Subsidiary of Parent; 

(d) Debt described in Section 7.1 of the Disclosure Letter as of the Closing Date, and any Permitted Refinancing
thereof; 
 (e) Contingent Obligations arising with respect to customary indemnification obligations in favor of purchasers
in connection with dispositions permitted under Section 7.4; 
 (f) Debt arising from the honoring by a bank or
other financial institution of a check, draft or similar instrument drawn against insufficient funds in the ordinary course of business, provided that such Debt is extinguished within 2 Business Days of notice to Parent or the relevant
Subsidiary of its incurrence; 
 (g) Debt incurred in connection with the financing of insurance premiums in the ordinary
course of business; 
 (h) Unsecured Debt owing to Pfizer arising out of or in connection with that certain Stock Purchase
Agreement between Pfizer and Parent dated as of December 11, 2009 not to exceed the aggregate principal amount of $25,000,000, plus accrued or capitalized interest thereon; provided that no payments on account of such Debt may be made during
the term of this Agreement without the Agent’s prior written consent, which may be withheld in Agent’s sole discretion; 

(i) Debt in connection with Parent’s obligations under the Assistance Agreement with respect to a grant to Parent in the
amount of $2,250,000; 
 (j) guaranties by the Borrower of the Debt of any Loan Party that is a Wholly-Owned Subsidiary of
Parent or guaranties by any Subsidiary thereof of the Debt of the Borrower in each case so long as such Debt is otherwise permitted under this Section 7.1(a), (b), (e), (k) or (o); 

(k) Subordinated Debt in an aggregate principal amount not to exceed $5,000,000; 

(l) unsecured Debt to trade creditors incurred in the ordinary course of business; 

  
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 (m) reimbursement obligations under corporate credit cards not to exceed $250,000
in the aggregate at any time; 
 (n) reimbursement obligations with respect to letters of credit for the account of lessors
not to exceed $2,000,000 in the aggregate at any time; 
 (o) other Debt in an amount not to exceed $100,000 in the aggregate
at any time outstanding; and 
 (p) Debt incurred in connection with interest rate, foreign currency and other swap
arrangements that are entered into to mitigate risk and not for speculative purposes. 
 7.2. Liens. Not, and not suffer or permit
any Loan Party or any other Subsidiary to, create or permit to exist any Lien on any of its real or personal properties, assets or rights of whatsoever nature (whether now owned or hereafter acquired), except: 

(a) Liens for Taxes or other governmental charges not at the time delinquent or thereafter payable without penalty, or being
diligently contested in good faith by appropriate proceedings and for which it maintains adequate reserves in accordance with GAAP; provided that no notice of any lien has been filed under the IRC; 

(b) (i) Liens of carriers, warehousemen, mechanics, customs brokers, landlords and materialmen and other similar Liens imposed
by law and (ii) Liens consisting of pledges or deposits incurred in connection with worker’s compensation, unemployment compensation and other types of social security (excluding Liens arising under ERISA) or in connection with surety
bonds, bids, performance bonds and similar obligations for sums not more than 30 days overdue or being diligently contested in good faith by appropriate proceedings and not involving any deposits or advances or borrowed money or the deferred
purchase price of property or services and, in each case, for which it maintains adequate reserves in accordance with GAAP; 

(c) Liens described in Section 7.2 of the Disclosure Letter as of the Closing Date and the replacement, extension
or renewal thereof upon or in the same property subject thereto arising out of the Permitted Refinancing of the Debt secured thereby; 

(d) Liens securing Debt permitted by Section 7.1(b); provided, however, that any such Lien (i) attaches only
to the property being leased or financed and any accessions thereto and proceeds thereof, and (ii) attaches to such property within 60 days of the acquisition thereof and attaches solely to the property so acquired and any accessions thereto
and proceeds thereof; 
 (e) attachments, appeal bonds, judgments and other similar Liens in connection with judgments the
existence of which do not constitute an Event of Default; 

  
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 (f) easements, encroachments, rights of way, leases, subleases, restrictions,
minor defects or irregularities in title and other similar Liens not interfering in any material respect with the ordinary conduct of the business of Parent or any Subsidiary; 

(g) any interest or title of a lessor or sublessor under any lease (other than a Capital Lease) or of a licensor or sublicensor
under any license, in each case permitted by this Agreement; 
 (h) leases, licenses, subleases or sublicenses granted to
third parties in the ordinary course of business which do not (i) interfere in any material respect with, or materially detract from the value of, the business of Parent and its Subsidiaries, taken as a whole, as determined by Parent in its
reasonable, good-faith business judgment or (ii) secure any Debt; 
 (i) Liens arising from precautionary uniform
commercial code financing statements filed under any lease (other than a Capital Lease) permitted by this Agreement; 
 (j)
Liens arising under the Loan Documents; 
 (k) bankers’ liens, rights of setoff and Liens in favor of financial
institutions incurred in the ordinary course of business arising in connection with deposit accounts or securities accounts held at such institutions solely to secure payment of fees and similar costs and expenses; 

(l) Liens on the Connecticut Assets; 

(m) Liens securing cash collateral (or Cash Equivalent Investments) for Debt incurred pursuant to Sections 7.1(m),
(n), (o) and (p); and 
 (n) Liens arising from judgments that do not constitute an Event of
Default. 
 7.3. Restricted Payments. Not, and not suffer or permit any Loan Party or any other Subsidiary to, (i) declare or
make any dividend payment or other distribution of assets, properties, cash, rights, obligations or securities on account of any Stock or Stock Equivalent issued by such Loan Party or Subsidiary, (ii) purchase, redeem or otherwise acquire for
value any Stock or Stock Equivalent issued by such Loan Party or Subsidiary now or hereafter outstanding or (iii) make any payment or prepayment of principal of, premium, if any, interest, fees, redemption, exchange, purchase, retirement,
defeasance, sinking fund or similar payment with respect to, Debt that is subordinated by its terms to the payment of the Obligations (except as permitted under the applicable subordination agreement satisfactory to the Agent) (the items described
in clauses (i), (ii) and (iii) above are referred to as “Restricted Payments”) except that (w) any Subsidiary of Parent may declare and pay dividends to, repay intercompany debt owed to, or make
internal profit-sharing payments to, Parent or any other Loan Party that is a Wholly-Owned Subsidiary of Parent, (x) (I) any Loan Party may purchase, redeem or acquire for value Stock or Stock Equivalent issued by any Loan Party that is a
Wholly Owned Subsidiary of the 

  
 40 

 
Parent, and (II) Parent may make repurchases from any present or former employee, director, officer or consultant (or the assigns, estate, heirs or current or former spouses thereof) upon the
death, disability or termination of employment of such employee, director, officer or consultant provided such repurchases do not exceed $1,000,000 in the aggregate per Fiscal Year and (y) Parent may make cash payments in lieu of the issuance
of fractional shares upon such conversion or in connection with the exercise of warrants or similar securities. For the avoidance of doubt, a capital contribution or other Investment in respect of the Stock of the Borrowers or any Subsidiary of the
Parent shall not constitute a Restricted Payment. 
 7.4. Mergers; Consolidations; Asset Sales. 

(a) Not, and not suffer or permit any Loan Party or any other Subsidiary to, be a party to any merger, consolidation or
amalgamation, except for any such merger, amalgamation or consolidation (i) of a Borrower with the other Borrower, of any Subsidiary of a Borrower into such Borrower (so long as such Borrower survives such merger) or with any Loan Party that is
a Wholly-Owned Subsidiary of Parent (so long as a Loan Party that is a Wholly-Owned Subsidiary of Parent survives such merger, amalgamation or consolidation), or (ii) in which the Obligations shall be Paid in Full prior to or concurrently with
the consummation of such transaction. 
 (b) Not, and not suffer or permit any Loan Party or any other Subsidiary to, sell,
transfer, dispose of, convey or lease any of its assets or the Capital Stock of any Loan Party (except for the Capital Stock of Parent) or any other Subsidiary, or sell or assign with or without recourse any receivables (any such transaction, a
“Disposition”), except for (i) Dispositions of inventory, worn-out or surplus equipment, all in the ordinary course of business, (ii) the abandonment of Intellectual Property permitted pursuant to
Section 6.3(d)(iii), or other Disposition of Intellectual Property so long as the decision to Dispose of such Intellectual Property is made for strategic business reasons and such Intellectual Property is not registered in the United
States, the United Kingdom, France, Spain, Italy or Germany, (iii) Dispositions of cash and Cash Equivalent Investments, (iv) licenses, sublicenses, leases or subleases (including any license or sublicense of Intellectual Property) granted
to third parties in the ordinary course of business not interfering with the business of the Loan Parties in any material respect as determined by Parent in its reasonable business judgment, (v) the granting of Liens permitted under
Section 7.2, Restricted Payments permitted by Section 7.3, transactions permitted by Section 7.4(a) and Investments permitted by Section 7.10, (vi) Dispositions resulting from any casualty or
other insured damage to, or any taking under power of eminent domain or by condemnation or similar proceeding of, any property or asset of any Loan Party provided the proceeds thereof are promptly applied to repair or replace such assets
(vii) other Dispositions not to exceed $1,000,000 per year,(viii) Dispositions among Loan Parties and (viii) Dispositions in which the Obligations shall be Paid in Full prior to or concurrently with the consummation of such transaction.

 (c) Not, and not suffer or permit any Loan Party or any other Subsidiary to, sell, transfer, dispose of, convey or license
any of its Intellectual Property other than as permitted by the foregoing clauses (a) or (b) of this Section 7.4. 

  
 41 

 7.5. Modification of Organizational Documents. Not waive, amend or modify, and not suffer
or permit any waiver, amendment or modification of, any term of the charter, limited liability company agreement, partnership agreement, articles of incorporation, by-laws or other organizational documents of either Borrower or any other Loan Party,
in each case except for those amendments and modifications that do not materially adversely affect the interests of the Agent or the Lender under the Loan Documents or in the Collateral (it being understood and agreed that any adverse impact on the
effectiveness or validity of any Collateral Document or the Liens granted to the Agent thereunder shall each be deemed to materially adversely affect such interests of the Agent and the Lender). 

7.6. Use of Proceeds. Not use the proceeds of the Loan for any purposes other than solely as expressly provided in
Section 2.1.2. 
 7.7. Transactions with Affiliates. Not, and not suffer or permit any Loan Party or any other Subsidiary
to, enter into any transaction or arrangement with any Affiliate of Parent, of any such Loan Party or of any such Subsidiary, except: 

(a) Restricted Payments permitted by Section 7.3, intercompany loans among Loan Parties permitted by
Section 7.1(c), transactions permitted by Section 7.1(j), (k), Section 7.4(a) and clause (viii) of Section 7.4(b) and Investments permitted by Section 7.10(a), (b), (j) or
(k); 
 (b) in the ordinary course of business and pursuant to the reasonable requirements of the business of such Loan
Party or such Subsidiary; provided that, in the case of this clause (b), such transaction shall be upon fair and reasonable terms no less favorable to such Loan Party than would be obtained in a comparable arm’s length transaction with a
Person not an Affiliate of Parent; 
 (c) payment of compensation and benefits (including customary indemnities) to officers,
directors and employees of the Loan Parties or another Subsidiary for actual services rendered to the Loan Parties or such Subsidiary in the ordinary course of business; 

(d) Investments permitted pursuant to Section 7.10(h) and (i); 

(e) advances for reasonable travel and entertainment expenses and reasonable relocation costs and expenses and other reasonable
loans and advances in the ordinary course of business; and 
 (f) Subordinated Debt and equity investments from investors, to
the extent not a Change of Control or otherwise prohibited hereunder. 

  
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 7.8. Inconsistent Agreements. Not, and not suffer or permit any other Loan Party or any
other Subsidiary to, enter into any agreement containing any provision which would (i) prohibit the Borrower or any other Loan Party from granting to the Agent a Lien on any of its assets that constitute Collateral or (ii) other than
pursuant to the Loan Documents, create or permit to exist or become effective any encumbrance or restriction on the ability of any other Subsidiary to (x) pay dividends or make other distributions to Parent or any Wholly-Owned Subsidiary, or
pay any Debt owed to Parent or any Wholly-Owned Subsidiary, (y) make loans or advances to Parent or any Wholly-Owned Subsidiary or (z) transfer any Collateral to Parent or any Wholly-Owned Subsidiary, except, in each case,
(a) negative pledges and restrictions (i) under agreements permitted under Section 7.1(b), (d), (m) ̧ (n), and (p), Section 7.2(g), (h) and (i) and Section 7.4
but solely to the extent any negative pledge or limitation on Liens relates to the property that is the subject of such Debt or applicable agreement or the cash securing such Debt or applicable obligations, and the proceeds and products thereof, and
(ii) in respect of the Connecticut Assets and the proceeds and products thereof, (b) customary restrictions on leases, subleases, licenses or asset sale agreements otherwise permitted hereby so long as such restrictions relate to the
assets subject thereto, (c) customary provisions restricting assignment of any agreement entered into in the ordinary course of business, and (d) prohibitions and limitations that exist pursuant to Applicable Law. 

7.9. Business Activities. Not, and not suffer or permit any Loan Party to, engage in any line of business other than the businesses
engaged in on the Closing Date and businesses reasonably related thereto. As of the Closing Date, the Borrowers, the other Loan Parties and any other Subsidiary thereof engage in the business of the development, manufacture, sale, licensing and
distribution of antibiotic therapies intended to advance patient care in infectious disease. 
 7.10. Investments. Not, and not
suffer or permit any Loan Party or any other Subsidiary to, make or permit to exist, any Investment in any other Person, except the following: 

(a) Investments between or among Parent and the Loan Parties that are Wholly-Owned Subsidiaries; 

(b) Investments constituting Debt permitted by Section 7.1(c); 

(c) Contingent Obligations constituting Debt permitted by Section 7.1; 

(d) Cash Equivalent Investments or investments maintained in securities accounts in compliance with Section 7.12;

 (e) Investments listed in Section 7.10 of the Disclosure Letter as of the Closing Date; 

(f) extensions of trade credit in the ordinary course of business; 

(g) notes payable, or stock or other securities issued by an account debtor pursuant to settlement in the ordinary course of
business of such account debtor’s accounts receivable owing to Parent or its Subsidiaries; 

  
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 (h) loans or advances to employees, officers and directors of a Loan Party for
reasonable travel and entertainment expenses and reasonable relocation costs and expenses and other ordinary business purposes; provided, however, that the aggregate outstanding principal amount of all loans and advances permitted
pursuant to this clause (h) shall not exceed $250,000 at any time; 
 (i) Investments consisting of non-cash
loans to employees, officers, directors or consultants for the purpose of purchasing Capital Stock in Parent so long as the proceeds of such loans are used entirely to pay the purchase price of such Capital Stock; 

(j) Investments consisting of the endorsement of negotiable instruments for deposit or collection or similar transactions in
the ordinary course of business; 
 (k) Investments by any Loan Party in any other Loan Party; 

(l) Loans to employees, officers or directors relating to the purchase of equity securities of any Loan Party or any of their
Subsidiaries pursuant to employee stock purchase plans or agreements approved by Parent’s Board of Directors not to exceed $250,000 in the aggregate in any fiscal year; 

(m) Investments (including debt obligations) received in connection with the bankruptcy or reorganization of customers or
suppliers and in settlement of delinquent obligations of, and other disputes with, customers or suppliers arising in the ordinary course of business; 

(n) Investments consisting of notes receivable of, or prepaid royalties and other credit extensions, to customers and suppliers
who are not Affiliates, in the ordinary course of business; provided that this paragraph shall not apply to Investments of Parent in any Subsidiary; and 

(o) other Investments in an aggregate amount not to exceed $250,000 at any time outstanding. 

7.11. Fiscal Year. Not, and not suffer or permit any other Loan Party to, change its Fiscal Year. 

7.12. Deposit Accounts and Securities Accounts. Not, and not suffer or permit any Loan Party to, maintain or establish any deposit
account or securities account in the United States other than the domestic deposit accounts and securities accounts set forth in Section 7.12 of the Disclosure Letter and any domestic deposit accounts of the Borrowers in connection with
Section 6.11(f) without prior written notice to the Agent and unless the Agent, the applicable Borrower or such other Loan Party and the bank or securities intermediary at which such deposit account or securities account, as applicable,
is to be opened or maintained enter into a Control Agreement regarding such deposit account or securities account, as applicable, on terms reasonably satisfactory to the Agent, provided that no such Control Agreement shall be required for any
deposit account, commodities account or securities account established to provide Liens 

  
 44 

 
permitted under Section 7.2(m). In addition, each of the Borrowers shall either (i) maintain its primary operating account in the United States in an account subject to a Control
Agreement or (ii) comply with the provisions of Section 6.11(f)(ii). 
 7.13. Sale-Leasebacks. Not and not suffer or
permit any Loan Party or any other Subsidiary to, engage in a sale leaseback, synthetic lease or similar transaction involving any of its assets. 

7.14. Hazardous Substances. Not, and not suffer or permit any other Loan Party to, cause or suffer to exist any release of any
Hazardous Substances at, to or from any real property owned, leased, subleased or otherwise operated or occupied by any Loan Party that would violate any Environmental Law, form the basis for any Environmental Claims or otherwise adversely affect
the value or marketability of any real property (whether or not owned by any Loan Party), other than such violations, Environmental Claims and effects that would not, in the aggregate, be reasonably be expected to have a Material Adverse Effect.
Notwithstanding the foregoing, under no circumstances will any Loan Party cause or suffer to exist any disposal of any Hazardous Substances at, on, under or in any real property owned, leased, subleased, or otherwise operated or occupied by any Loan
Party. 
 7.15. ERISA Liability. Not suffer or permit any liability under ERISA and the sponsorship of any “pension plan”
or any liability subject to Title IV of ERISA. 
 7.16. Liquidity. Not suffer or permit Liquidity to be less than $2,000,000 at any
time. 
  

	Section 8.	Events of Default; Remedies. 

 8.1. Events of Default. Each of the following shall
constitute an Event of Default under this Agreement: 
 8.1.1. Non-Payment of Credit Agreement. Any default in the payment when due
of the principal of the Loan or of any default not cured within 3 Business Days of any interest, fee, or other amount payable hereunder, including any payment in respect of any amount due under any other Loan Document, shall occur. 

8.1.2. Default Under Other Debt. 

(a) Any default in the payment of principal or interest when due (giving effect to all applicable grace periods, if any) shall
occur under the terms applicable to any Debt (other than the Obligations) of any Loan Party having an aggregate principal amount (for all such Debt so affected and including amounts owing to all creditors under any combined or syndicated credit
arrangement) exceeding $250,000; and 
 (b) Any default shall occur under the terms applicable to any Debt (other than the
Obligations) of any Loan Party having an aggregate principal amount (for all such Debt so affected and including undrawn committed or available amounts and amounts owing to all creditors under any combined or syndicated credit arrangement) exceeding
$250,000 and such default shall result 

  
 45 

 
in the acceleration of the maturity of such Debt or permit the holder or holders thereof, or any trustee or agent for such holder or holders, to cause such Debt to become due and payable (or
require either Borrower or any other Loan Party to purchase or redeem such Debt or post cash collateral in respect thereof) prior to its expressed maturity. 

8.1.3. Bankruptcy; Insolvency. (i) Any Loan Party becomes insolvent or generally fails to pay, or admits in writing its inability
to pay, debts as they become due; (ii) any Loan Party commences any case, proceeding or other action (x) under any existing or future law of any jurisdiction, domestic or foreign, relating to bankruptcy, insolvency, reorganization or
relief of debtors, seeking to have an order for relief entered with respect to it, or seeking to adjudicate it a bankrupt or insolvent, or seeking reorganization, arrangement, adjustment, winding up, liquidation, dissolution, composition or other
relief with respect to it or its debts, or (y) seeking appointment of a receiver, trustee, custodian, conservator or other similar official for it or for all or any substantial part of its assets; or (iii) there shall be commenced against
any Loan Party any case, proceeding or other action of a nature referred to in clause (ii) above that (x) results in the entry of an order for relief or any such adjudication or appointment or (y) remains undismissed or undischarged
for a period of 60 days; (iv) there shall be commenced against any Loan Party any case, proceeding or other action seeking issuance of a warrant of attachment, execution, distraint or similar process against all or any substantial part of its
assets that results in the entry of an order for any such relief that shall not have been vacated, discharged, or stayed or bonded pending appeal within 60 days from the entry thereof; (v) any Loan Party shall take any action in furtherance of,
or indicating its consent to, approval of, or acquiescence in, any of the acts set forth in clause (ii), (iii) or (iv) above; or (vi) any Loan Party shall make a general assignment for the benefit of its creditors. 

8.1.4. Non-Compliance with Loan Documents. (a) Failure by the Borrower or any other Loan Party to comply with or to perform any
covenant set forth in Sections 6.1(a) (with respect to existence), 6.5, 6.9, 6.11 and 7; or (b) failure by either Borrower or any other Loan Party to comply with or to perform any other provision of this
Agreement or any other Loan Document applicable to it (and not constituting an Event of Default under any other provision of this Section 8), and continuance of such failure described in this clause (b) for 30 days. 

8.1.5. Representations; Warranties. Any representation or warranty made by or in respect of any Loan Party herein or any other Loan
Document is breached or is false or misleading in any material respect (without duplication of any materiality qualifier contained therein), or any schedule, certificate, financial statement, report, notice or other writing furnished by any Loan
Party to the Agent or the Lender in connection herewith is false or misleading in any material respect on the date as of which the facts therein set forth are stated or certified. 

8.1.6. Judgments. 

(a) Final judgments which exceed an aggregate of $250,000 (to the extent not covered by third-party insurance as to which the
insurer has been notified of such judgment or order and does not dispute coverage therefor) shall be rendered against any Loan Party and shall not have been paid, discharged or vacated or had execution thereof stayed pending appeal within 30 days
after entry or filing of such judgments; or 

  
 46 

 (b) One or more non-monetary judgments, orders or decrees shall be rendered
against any one or more of the Loan Parties or any of their respective Subsidiaries which has had or would reasonably be expected to have, either individually or in the aggregate, a Material Adverse Effect, and there shall be any period of 30
consecutive days during which a stay of enforcement of such judgment or order, by reason of a pending appeal or otherwise, shall not be in effect. 

8.1.7. Invalidity of Collateral Documents. Any Collateral Document shall cease to be in full force and effect; or any Loan Party or
other grantor or pledgor (or any Person by, through or on behalf of any Loan Party, grantor or pledgor) shall contest in any manner the validity, binding nature or enforceability of any Collateral Document. 

8.1.8. Invalidity of Subordination Provisions. Any subordination provision in any document or instrument governing Debt that is
intended to be subordinated to the Obligations or any subordination provision in any subordination agreement that relates to any such Debt, or any subordination provision in any guaranty by any Loan Party of any such Debt, shall cease to be in full
force and effect, or any Person (including the holder of any applicable Debt) shall contest in any manner the validity, binding nature or enforceability of any such provision. 

8.1.9. Change of Control. (a) A Change of Control shall occur, or (b) a “Change of Control” shall occur, as defined
under any agreement evidencing Debt of a Loan Party with an aggregate principal amount of $1,000,000 or greater, and such “Change of Control” is a default, or would require the payment in full of such Debt (or the offer to purchase such
Debt to be made by a Loan Party. 
 8.2. Remedies. If any Event of Default described in Section 8.1.3 shall occur, the
Loan and all other Obligations shall become immediately due and payable and all outstanding Commitments shall terminate, all without presentment, demand, protest or notice of any kind; and, if any other Event of Default shall occur and be
continuing, the Agent may, and upon the written request of the Lender shall, declare all or any part of the Loan and other Obligations to be due and payable and/or all or any part of the Commitments then outstanding to be terminated, whereupon the
Loan and other Obligations shall become immediately due and payable (in whole or in part, as applicable), and such Commitments shall immediately terminate (in whole or in part, as applicable), all without presentment, demand, protest or notice of
any kind. The Agent shall promptly advise the Borrowers of any such declaration, but failure to do so shall not impair the effect of such declaration. Any cash collateral delivered hereunder shall be applied by the Agent to any remaining Obligations
and any excess remaining after the Obligations shall have been Paid in Full shall be delivered to the Borrowers or as a court of competent jurisdiction may elect. Upon the declaration of the Obligations to be, or the Obligations becoming, due and
payable pursuant to this Section 8.2 such Obligations shall bear interest at the Default Rate as provided in Section 2.3.1. 

  
 47 

	Section 9.	The Agent. 

 9.1. Appointment; Authorization. 

(a) Lender hereby irrevocably appoints, designates and authorizes the Agent to take such action on its behalf under the
provisions of this Agreement and each other Loan Document and to exercise such powers and perform such duties as are expressly delegated to it by the terms of this Agreement or any other Loan Document, together with such powers as are reasonably
incidental thereto. Notwithstanding any provision to the contrary contained elsewhere in this Agreement or in any other Loan Document, the Agent shall not have any duty or responsibility except those expressly set forth herein, nor shall the Agent
have or be deemed to have any fiduciary relationship with the Lender, and no implied covenants, functions, responsibilities, duties, obligations or liabilities shall be read into this Agreement or any other Loan Document or otherwise exist against
the Agent. 
 9.2. Delegation of Duties. The Agent may execute any of its duties under this Agreement or any other Loan Document by
or through agents, employees or attorneys in fact and shall be entitled to advice of counsel concerning all matters pertaining to such duties. The Agent shall not be responsible for the negligence or misconduct of any agent or attorney in fact that
it selects with reasonable care. 
 9.3. Limited Liability. None of the Agent or any of its directors, officers, employees or agents
shall (a) be liable for any action taken or omitted to be taken by any of them under or in connection with this Agreement or any other Loan Document or the transactions contemplated hereby (except to the extent resulting from its own gross
negligence or willful misconduct as determined in a final non-appealable judgment by a court of competent jurisdiction), or (b) be responsible in any manner to the Lender for any recital, statement, representation or warranty made by any Loan
Party or Affiliate of any Loan Party, or any officer thereof, contained in this Agreement or in any other Loan Document, or in any certificate, report, statement or other document referred to or provided for in, or received by the Agent under or in
connection with, this Agreement or any other Loan Document, or the validity, effectiveness, genuineness, enforceability or sufficiency of this Agreement or any other Loan Document (or the creation, perfection or priority of any Lien or security
interest therein), or for any failure of any Loan Party or any other party to any Loan Document to perform its Obligations hereunder or thereunder. The Agent shall not be under any obligation to the Lender to ascertain or to inquire as to the
observance or performance of any of the agreements contained in, or conditions of, this Agreement or any other Loan Document, or to inspect the properties, books or records of any Loan Party or Affiliate of any Loan Party. 

9.4. Successor Agent. The Agent may resign as the Agent at any time upon 30 days’ prior notice to the Lender. If the Agent resigns
under this Agreement, the Lender shall, with (so long as no Event of Default exists) the consent of the Borrower (which shall not be unreasonably withheld or delayed), appoint a successor agent for the Lender. If no successor agent is appointed
prior to the effective date of the resignation of the Agent, the Agent may appoint, on behalf of the Lender after consulting with the Lender and (so long as no Event of Default exists) 

  
 48 

 
the Borrowers, a successor agent. Upon the acceptance of its appointment as successor agent hereunder, such successor agent shall succeed to all the rights, powers and duties of the retiring
Agent and the term “the Agent” shall mean such successor agent, and the retiring Agent’s appointment, powers and duties as the Agent shall be terminated. After any retiring the Agent’s resignation hereunder as the Agent, the
provisions of this Section 9 and Sections 10.4 and 10.5 shall continue to inure to its benefit as to any actions taken or omitted to be taken by it while it was the Agent under this Agreement. If no successor agent has
accepted appointment as the Agent by the date which is 30 days following a retiring the Agent’s notice of resignation, the retiring Agent’s resignation shall nevertheless thereupon become effective and the Lender shall perform all of the
duties of the Agent hereunder until such time as the Lender shall appoint a successor agent as provided for above. 
 9.5. Collateral
Matters. Lender irrevocably authorizes the Agent, at its option and in its discretion, to release any Lien granted to or held by the Agent under any Collateral Document (i) when all Obligations have been Paid in Full; (ii) constituting
property sold or to be sold or disposed of as part of or in connection with any sale or other disposition permitted hereunder (it being agreed and understood that the Agent may conclusively rely without further inquiry on a certificate of an officer
of the Borrower as to the sale or other disposition of property being made in compliance with this Agreement); or (iii) subject to Section 10.1, if approved, authorized or ratified in writing by the Lender. Upon request by the Agent
at any time, the Lender will confirm in writing the Agent’s authority to release types or items of Collateral pursuant to this Section 9.5. The Agent shall have the right, in accordance with the Collateral Documents, to sell, lease
or otherwise dispose of any Collateral for cash, credit or any combination thereof, and the Agent may purchase any Collateral at public or, if permitted by law, private sale and, in lieu of actual payment of the purchase price, may credit bid and
setoff the amount of such price against the Obligations. 
  

	Section 10.	Miscellaneous. 

 10.1. Waiver; Amendments. No delay on the part of the Agent or
the Lender in the exercise of any right, power or remedy shall operate as a waiver thereof, nor shall any single or partial exercise by any of them of any right, power or remedy preclude other or further exercise thereof, or the exercise of any
other right, power or remedy. No amendment, modification or waiver of, or consent with respect to, any provision of this Agreement, the Notes or any of the other Loan Documents (or any subordination and intercreditor agreement or other subordination
provisions relating to any other Debt) shall in any event be effective unless the same shall be in writing and approved by the Agent and the Required Lenders, and then any such amendment, modification, waiver or consent shall be effective only in
the specific instance and for the specific purpose for which given. Notwithstanding the foregoing, no amendment or modification shall be effective that would (i) extend the Maturity Date; (ii) amend this Section 10.1; (iii) amend
the definition of Required Lenders; (iv) increase the amount of Loans hereunder; (vi) release Collateral, except as currently contemplated by the Loan Documents; or (vii) release any Loan Party from liability for any Obligations, in
each case, without the consent of all lenders holding Loans at such time. No provision of Section 9 or other provision of this Agreement affecting the Agent in its capacity as such shall be amended, modified or waived without the consent
of the Agent. 

  
 49 

 10.2. Notices. All notices hereunder shall be in writing (including facsimile
transmission) and shall be sent to the applicable party at its address shown on Annex I or at such other address as such party may, by written notice received by the other parties, have designated as its address for such purpose. Notices sent
by facsimile or other electronic transmission shall be deemed to have been given when sent; notices sent to the Borrowers by mail shall be deemed to have been given three Business Days after the date when sent by registered or certified mail,
postage prepaid; and notices sent by hand delivery or overnight courier service shall be deemed to have been given when received. 
 10.3.
Costs; Expenses. Each Borrower agrees, jointly and severally, to pay on demand (a) all reasonable out-of-pocket costs and expenses of the Agent and the Lender (including Legal Costs) in connection with the administration (including
perfection and protection of Collateral subsequent to the Closing Date) of this Agreement, the other Loan Documents and all other documents provided for herein or delivered or to be delivered hereunder or in connection herewith (including any
proposed or actual amendment, supplement or waiver to any Loan Document), and (b) all reasonable out-of-pocket costs and expenses (including Legal Costs) incurred by the Agent and the Lender in connection with the collection of the Obligations
and enforcement of this Agreement, the other Loan Documents or any such other documents. All Obligations provided for in this Section 10.3 shall survive repayment of the Loan, cancellation of the Notes and termination of this Agreement.

 10.4. Indemnification by the Borrowers. In consideration of the execution and delivery of this Agreement by the Agent and
the Lender and the agreement to extend the Commitments provided hereunder, each of the Borrowers hereby, jointly and severally, agrees to indemnify, exonerate and hold the Agent, the Lender and each of the officers, directors, employees, Affiliates,
controlling persons, advisors and agents of the Agent and the Lender (each a “the Lender Party”) free and harmless from and against any and all actions, causes of action, suits, losses, liabilities (including, without limitation,
strict liabilities), obligations, damages, penalties, judgments, fines, disbursements, expenses and costs, including Legal Costs (collectively, the “Indemnified Liabilities”), incurred by the Lender Parties or asserted against the
Lender Party by any Person (including in connection with any action, suit or proceeding brought by any Holder, either Borrower, any other Loan Party or any Lender Party) as a result of, or arising out of, or relating to the execution, delivery,
performance, administration or enforcement of this Agreement or any other Loan Document, the use of proceeds of the Loans, or the violation of, noncompliance with or liability under, any Environmental Law applicable to the operations of any Loan
Party, except to the extent any such Indemnified Liabilities result from the applicable Lender Party’s own gross negligence, willful misconduct, or material breach of any Loan Document, in each case as determined by a court of competent
jurisdiction in a final, non-appealable determination. If and to the extent that the foregoing undertaking may be unenforceable for any reason, each of Parent and the Borrowers hereby agrees, jointly and severally, to make the maximum contribution
to the payment and satisfaction of each of the Indemnified Liabilities which is permissible under Applicable Law. All Obligations provided for in this Section 10.4 shall survive repayment of the Loan, cancellation of the Notes, any
foreclosure under, or any modification, release or discharge of, any or all of the Collateral Documents and termination of this Agreement. This Section 10.4 shall not apply with respect to Taxes, other than Taxes that represent losses,
claims, damages, etc. arising from any non-Tax claim. 

  
 50 

 10.5. Marshaling; Payments Set Aside. Neither the Agent nor the Lender shall be under any
obligation to marshal any assets in favor of the Borrowers or any other Person or against or in payment of any or all of the Obligations. To the extent that either Borrower or any other Loan Party makes a payment or payments to the Agent or the
Lender, or the Agent or the Lender enforces its Liens or exercises its rights of set-off, and such payment or payments or the proceeds of such enforcement or set-off or any part thereof are subsequently invalidated, declared to be fraudulent or
preferential, set aside or required (including pursuant to any settlement entered into by the Agent or the Lender in its discretion) to be repaid to a trustee, receiver or any other party in connection with any bankruptcy, insolvency or similar
proceeding, or otherwise, then (a) to the extent of such recovery, the obligation hereunder or part thereof originally intended to be satisfied shall be revived and continued in full force and effect as if such payment had not been made or such
enforcement or setoff had not occurred and (b) the Lender severally agrees to pay to the Agent upon demand its ratable share of the total amount so recovered from or repaid by the Agent to the extent paid to such Lender. 

10.6. Nonliability of the Lender. The relationship between the Borrowers on the one hand and the Lender and the Agent on the other hand
shall be solely that of borrower and lender. Neither the Agent nor the Lender shall have any fiduciary responsibility to either Borrower or any other Loan Party. Neither the Agent nor the Lender undertakes any responsibility to either Borrower or
any other Loan Party to review or inform (including payment of all outstanding principal) such Borrower or any other Loan Party of any matter in connection with any phase of such Borrower’s or any other Loan Party’s business or operations.
Execution of this Agreement by the Borrowers constitutes a full, complete and irrevocable release of any and all claims which the Borrower may have at law or in equity in respect of all prior discussions and understandings, oral or written, relating
to the subject matter of this Agreement and the other Loan Documents. Neither Borrower, the Agent nor the Lender shall have any liability with respect to, and each Borrower, Agent and Lender each hereby waives, releases and agrees not to sue for,
any special, indirect, punitive or consequential damages or liabilities. 
 10.7. Confidentiality. The Agent and the Lender agree to
maintain as confidential all information provided to them designated as confidential by any Loan Party, except that the Agent and the Lender may disclose such information (a) to Persons employed or engaged by the Agent or such Lender or any of
their Affiliates (including collateral managers of the Lender) in evaluating, approving, structuring or administering the Loan and the Commitments (provided that such persons have agreed to comply with the covenant contained in this
Section 10.7); (b) to any assignee or participant or potential assignee or participant that has agreed to comply with the covenant contained in this Section 10.7 (and any such assignee or participant or potential assignee or
participant may disclose such information to Persons employed or engaged by them as described in clause (a) above); (c) as required or requested by any federal or state regulatory authority or examiner, or as reasonably believed by the
Agent or such Lender to be compelled by any court decree, subpoena or legal or administrative order or process; (d) as, on the advice of the Agent’s or such Lender’s counsel, is required by law; (e) in connection with the
exercise of any right or remedy under the Loan Documents or in connection with any litigation to which the Agent or such Lender is a party; (f) to any nationally recognized rating agency or investor of the Lender that requires access to
information about the Lender’s investment portfolio in connection with ratings issued or investment decisions with respect to such Lender; or (g) that ceases to be confidential through no fault of the Agent or the Lender; provided,
that in each case, the Agent 

  
 51 

 
and any such Lender provides prior written notice of such required disclosure (or in the event prior written notice is not possible, as promptly as reasonably practicable after such required
disclosure) to Parent and takes reasonable and lawful actions to avoid and/or minimize the extent of such disclosure. 
 10.8.
Captions. Captions used in this Agreement are for convenience only and shall not affect the construction of this Agreement. 
 10.9.
Nature of Remedies. All Obligations of the Borrowers and rights of the Agent and the Lender expressed herein or in any other Loan Document shall be in addition to and not in limitation of those provided by Applicable Law. No failure to
exercise and no delay in exercising, on the part of the Agent or the Lender, any right, remedy, power or privilege hereunder, shall operate as a waiver thereof; nor shall any single or partial exercise of any right, remedy, power or privilege
hereunder preclude any other or further exercise thereof or the exercise of any other right, remedy, power or privilege. 
 10.10.
Counterparts. This Agreement may be executed in any number of counterparts and by the different parties hereto on separate counterparts and each such counterpart shall be deemed to be an original, but all such counterparts shall together
constitute but one and the same Agreement. Receipt by telecopy or electronic transmission of any executed signature page to this Agreement or any other Loan Document shall constitute effective delivery of such signature page. 

10.11. Severability. The illegality or unenforceability of any provision of this Agreement or any instrument or agreement required
hereunder shall not in any way affect or impair the legality or enforceability of the remaining provisions of this Agreement or any instrument or agreement required hereunder. 

10.12. Entire Agreement. This Agreement, together with the other Loan Documents, embodies the entire agreement and understanding among
the parties hereto and supersedes all prior or contemporaneous agreements and understandings of such Persons, verbal or written, relating to the subject matter hereof and thereof and any prior arrangements made with respect to the payment by the
Borrower of (or any indemnification for) any fees, costs or expenses payable to or incurred (or to be incurred) by or on behalf of the Agent or the Lender 

10.13. Successors; Assigns. This Agreement shall be binding upon Parent, each Borrower, each other Loan Party party hereto, the Lender
and the Agent and their respective successors and assigns, and shall inure to the benefit of Parent, each Borrower, each other Loan Party party hereto, the Lender and the Agent and the successors and assigns of the Lender and the Agent. No other
Person shall be a direct or indirect legal beneficiary of, or have any direct or indirect cause of action or claim in connection with, this Agreement or any of the other Loan Documents. Parent, each Borrower and each other Loan Party party hereto
may not assign or transfer any of its rights or Obligations under this Agreement without the prior written consent of the Agent and the Lender. The Lender may sell, transfer, or assign all or less than all of its rights and obligations hereunder to
any Person pursuant to assignment documentation reasonably acceptable to Lender and such assignee and with the consent of the Borrowers (such consent not to be unreasonably withheld); provided, that no such consent of the Borrowers will be
required 

  
 52 

 
during the occurrence and continuance of an Event of Default. The Agent (acting solely for this purpose as the agent of each Borrower) shall maintain a register for the recordation of the names
and addresses of the Lender and its assignees, and the amounts of principal and interest owing to any of them hereunder from time to time (the “Register”). The entries in the Register shall be conclusive absent manifest error, and
the Borrowers, Agent, the Lender and its assignees shall treat each person whose name is recorded in the Register pursuant to the terms hereof as a Lender hereunder for all purposes of this Agreement and all references to the Lender in this
Agreement shall include any such assignee of the Lender. 
 10.14. Governing Law. THIS AGREEMENT AND EACH NOTE SHALL BE A CONTRACT
MADE UNDER AND GOVERNED BY THE INTERNAL LAWS OF THE STATE OF NEW YORK APPLICABLE TO CONTRACTS MADE AND TO BE PERFORMED ENTIRELY WITHIN SUCH STATE, WITHOUT REGARD TO CONFLICT OF LAWS PRINCIPLES (OTHER THAN SECTION 5-1401 OF THE NEW YORK GENERAL
OBLIGATIONS LAW). 
 10.15. Forum Selection; Consent to Jurisdiction; Service of Process. ANY LITIGATION BASED HEREON, OR ARISING OUT
OF, UNDER, OR IN CONNECTION WITH THIS AGREEMENT OR ANY OTHER LOAN DOCUMENT, SHALL BE BROUGHT AND MAINTAINED EXCLUSIVELY IN THE COURTS OF THE STATE OF NEW YORK OR IN THE UNITED STATES DISTRICT COURT FOR THE SOUTHERN DISTRICT OF NEW YORK;
PROVIDED THAT ANY SUIT SEEKING ENFORCEMENT AGAINST ANY COLLATERAL OR OTHER PROPERTY MAY BE BROUGHT, AT AGENT’S OPTION, IN THE COURTS OF ANY JURISDICTION WHERE SUCH COLLATERAL OR OTHER PROPERTY MAY BE FOUND. EACH LOAN PARTY HEREBY
EXPRESSLY AND IRREVOCABLY SUBMITS TO THE JURISDICTION OF THE COURTS OF THE STATE OF NEW YORK AND OF THE UNITED STATES DISTRICT COURT FOR THE SOUTHERN DISTRICT OF NEW YORK FOR THE PURPOSE OF ANY SUCH LITIGATION AS SET FORTH ABOVE. EACH LOAN PARTY
FURTHER IRREVOCABLY CONSENTS TO THE SERVICE OF PROCESS BY REGISTERED MAIL, POSTAGE PREPAID, OR BY PERSONAL SERVICE WITHIN OR WITHOUT THE STATE OF NEW YORK. EACH LOAN PARTY HEREBY EXPRESSLY AND IRREVOCABLY WAIVES, TO THE FULLEST EXTENT PERMITTED BY
LAW, ANY OBJECTION WHICH IT MAY NOW OR HEREAFTER HAVE TO THE LAYING OF VENUE OF ANY SUCH LITIGATION BROUGHT IN ANY SUCH COURT REFERRED TO ABOVE AND ANY CLAIM THAT ANY SUCH LITIGATION HAS BEEN BROUGHT IN AN INCONVENIENT FORUM. Each foreign Loan Party
hereby appoints CT Corporation System, 111 Eighth Avenue, New York, New York 10011, as such Loan Party’s agent where notices and demands to or upon such Loan Party in respect of this Agreement, the Security Agreement, the Intellectual Property
Security Agreements (as defined in the Security Agreement) or the Subsidiary Guaranties may be served (without prejudice to the right of the Agent or the Lender to serve process in any other manner permitted by law). If for any reason such process
agent is unable to serve as such, such Loan Party will within 30 days appoint a substitute process agent located in the State of New York and give notice of such appointment to the Agent. 

10.16. Waiver of Jury Trial. EACH LOAN PARTY, AGENT AND LENDER HEREBY WAIVES ANY RIGHT TO A TRIAL BY JURY IN ANY ACTION OR PROCEEDING
TO 

  
 53 

 
ENFORCE OR DEFEND ANY RIGHTS UNDER THIS AGREEMENT, ANY NOTE, ANY OTHER LOAN DOCUMENT AND ANY AMENDMENT, INSTRUMENT, DOCUMENT OR AGREEMENT DELIVERED OR WHICH MAY IN THE FUTURE BE DELIVERED IN
CONNECTION HEREWITH OR THEREWITH OR ARISING FROM ANY LENDING RELATIONSHIP EXISTING IN CONNECTION WITH ANY OF THE FOREGOING, AND AGREES THAT ANY SUCH ACTION OR PROCEEDING SHALL BE TRIED BEFORE A COURT AND NOT BEFORE A JURY. 

10.17. Collateral Agent. Lender hereby appoints PDL BioPharma, Inc. as its collateral agent under the Security Agreement and agrees
that in so acting PDL BioPharma, Inc. will have all the rights, protections, exculpations, indemnities and other benefits provided to PDL BioPharma, Inc. under Section 9 hereof, and authorizes and directs PDL BioPharma, Inc. to take or
refrain from taking any and all action that it deems necessary or advisable in fulfilling its role as Collateral Agent under the Security Agreement. 

10.18. Limitation of Liability. Notwithstanding anything to the contrary contained in this Agreement or in the other Loan Documents,
the parties agree that: (a) no Borrower that is a controlled foreign corporation, as defined in Section 957 of the Code (a “CFC”) (or any other Loan Party that is organized in any jurisdiction outside of the United States
and is a CFC) shall be liable for any obligation of the Parent, Vicuron, Durata U.S. (or any other Loan Party that is organized in the United States or any state or territory thereof) arising under or with respect to any of the Loan Documents; and
(b) neither the Agent nor any Lender nor any Affiliate thereof, may set-off or apply any deposits of a Borrower that is a CFC (or any other Loan Party that is organized in any jurisdiction outside of the United States that is a CFC) or any
other obligations at the time owing to or for the credit of the account of any Borrower that is a CFC (or any other Loan Party that is organized in any jurisdiction outside of the United States that is a CFC), against any or all of the obligations
of the Parent, Vicuron, Durata U.S. (or any other Loan Party that is organized in the United States or any state or territory thereof), and (c) no Lien or Security Interest in any Property of a Borrower that is a CFC (or any other Loan Party
that is organized in any jurisdiction outside of the United States that is a CFC) shall secure any Obligations of the Parent, Vicuron, Durata U.S. (or any other Loan Party that is organized in the United States or a state or territory thereof) as
a Guarantor under this Agreement or the other Loan Documents. 
 [signature pages follow] 

  
 54 

 IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be duly executed and
delivered by their duly authorized officers as of the date first set forth above. 
  

							
	BORROWERS:
	
	 DURATA THERAPEUTICS HOLDING C.V.,

a limited partnership organized under the laws of the Netherlands

		
	By:	 	Durata Therapeutics, Inc. its general partner
			
		 	By:	 	 /s/ Corey N. Fishman

		 		 	Name:	 	Corey N. Fishman
		 		 	Title:	 	Secretary, Treasurer, Chief Financial Officer and Chief Operating Officer

 
							
	
	 DURATA THERAPEUTICS INTERNATIONAL B.V.,

a private company with limited liability incorporated under the laws of the Netherlands

		
	By:	 	 /s/ Corey N. Fishman

		 	Name:	 	Corey N. Fishman
		 	Title:	 	Managing Director

  

					
	PARENT:
	
	 DURATA THERAPEUTICS, INC.,
 a
Delaware corporation

		
	By:	 	 /s/ Corey N. Fishman

		 	Name:	 	Corey N. Fishman
		 	Title:	 	Secretary, Treasurer, Chief Financial Officer and Chief Operating Officer

  

[SIGNATURE PAGE TO CREDIT AGREEMENT] 

 
					
	GUARANTORS:
	
	 VICURON PHARMACEUTICALS INC.,

a Delaware corporation

		
	By:	 	 /s/ Corey N. Fishman

		 	Name:	 	Corey N. Fishman
		 	Title:	 	Secretary and Treasurer
	
	 DURATA THERAPEUTICS U.S. LIMITED,

a Delaware corporation

		
	By:	 	 /s/ Corey N. Fishman

		 	Name:	 	Corey N. Fishman
		 	Title:	 	President, Secretary and Treasurer

  

[SIGNATURE PAGE TO CREDIT AGREEMENT] 

 
					
	LENDER AND AGENT:
	
	 PDL BIOPHARMA, INC.,
 a
Delaware corporation

		
	By:	 	 /s/ John P. McLaughlin

		 	Name:	 	John P. McLaughlin
		 	Title:	 	President and Chief Executive Officer

  

[SIGNATURE PAGE TO CREDIT AGREEMENT] 

 ANNEX I 

Addresses 
 LOAN PARTIES 

Address for Notices: 
 200 South Wacker Drive, Suite 2550 

Chicago, Illinois 60606 
 Attn: Corey N. Fishman, Chief Financial
Officer 
 Telephone: (312) 219-7000 
 Fax:
(312) 612-5298 
 Email: cfishman@duratatherapeutics.com 

AGENT 
 PDL BioPharma, Inc., 

as the Agent and the Lender 
 Address for Notices: 

932 Southwood Boulevard 
 Incline Village, NV 89451 

Attention: General Counsel 
 Telephone: (775) 832-8500 

Facsimile: (775) 832-8501 

  
 II-1 

 EXHIBIT A 

COMPLIANCE CERTIFICATE 
 Date:
                    , 201     

This Compliance Certificate (this “Certificate”) is given by DURATA THERAPEUTICS, INC., a Delaware corporation
(“Parent”), pursuant to that certain Credit Agreement dated as of October 31, 2013 (the “Credit Agreement”; capitalized terms used and not defined herein shall have the meaning set forth in the Credit
Agreement), among DURATA THERAPEUTICS HOLDING C.V., a limited partnership organized under the laws of the Netherlands (“Durata C.V.”), DURATA THERAPEUTICS INTERNATIONAL B.V., a private company with limited liability incorporated
under the laws of the Netherlands, Parent, certain subsidiaries of Parent that are party thereto, and PDL BIOPHARMA, INC., a Delaware corporation, as Lender and Agent (“Agent”). 

Pursuant to Section 6.1.4 of the Credit Agreement, the undersigned hereby certifies that he or she is the duly appointed,
qualified, and acting chief financial officer of Parent, and in such capacity, certifies on behalf of Parent to Agent that: 

1. The financial statements delivered with this Certificate have been prepared in accordance with GAAP and fairly present the
consolidated financial condition and results of operations of Parent and its Subsidiaries as of the dates of and for the periods covered by such financial statements (except for the absence of footnotes and subject to year-end adjustments); 

2. Such officer has reviewed the terms of the Credit Agreement and made, or caused to be made under such officer’s
supervision, a review in reasonable detail of the transactions and conditions of Parent and its Subsidiaries during the accounting period covered by such financial statements; and 

3. Such officer has no knowledge of, the existence, as of the date hereof, of any condition or event that constitutes a Default
or an Event of Default, except as set forth on Schedule 1 hereto1, which includes a description of such Default or Event of Default and what action, if any, are being taken to cure such Default or Event of Default. 

IN WITNESS WHEREOF, Parent has caused this Certificate to be executed as of the date first written above. 

 

			
	 DURATA THERAPEUTICS, INC.,
 a
Delaware corporation

		
	By:	 	  

	Name:	 	
	Title:	 	

  

	1	Schedule 1 should be prepared and attached if a Default or Event of Default has occurred and is continuing. 

 EXHIBIT B 

FORM OF TERM NOTE 
  

			
	$[        .    ]	  	New York, New York
		  	[                 ,         ]

 FOR VALUE RECEIVED, the undersigned,
[                    ], a [                    ]
(the “Borrower”), hereby unconditionally promises to pay to PDL BIOPHARMA, INC., a Delaware corporation (the “Lender”), or its registered assigns at the address specified in the Credit Agreement (as hereinafter
defined) in lawful money of the United States and in immediately available funds, the unpaid amount of the Obligations outstanding under the Credit Agreement. Amounts evidenced hereby shall be paid in the amounts and on the dates specified in
Section 2 of the Credit Agreement. 
 The holder of this Note is authorized to endorse on the schedules annexed hereto and made a part
hereof or on a continuation thereof which shall be attached hereto and made a part hereof the date, the type and amount of the Obligations and the date, type and amount of each payment or prepayment in respect thereof. Each such endorsement shall
constitute prima facie evidence of the accuracy of the information endorsed. The failure to make any such endorsement or any error in any such endorsement shall not affect the Obligations. 

This Note (a) is one of the Notes referred to in the Credit Agreement, dated as of October [31], 2013 (as amended, supplemented or
otherwise modified from time to time, the “Credit Agreement”), by and among DURATA THERAPEUTICS HOLDING C.V., a limited partnership organized under the laws of the Netherlands, DURATA THERAPEUTICS INTERNATIONAL B.V., a private
company with limited liability incorporated under the laws of the Netherlands having its official seat in Amsterdam, the Netherlands, and which is registered with the Dutch trade register under number 55527221, DURATA THERAPEUTICS, INC., a Delaware
corporation (“Parent”), the Lender, each Subsidiary of Parent from time to time party thereto and PDL BIOPHARMA, INC., a Delaware corporation, not individually, but as the Agent (the “Agent”) and (b) is subject
to the provisions of the Credit Agreement. This Note is secured and guaranteed as provided in the Loan Documents. Reference is hereby made to the Loan Documents for a description of the properties and assets in which a security interest has been
granted, the nature and extent of the security and the guarantees, the terms and conditions upon which the security interests and each guarantee were granted and the rights of the holder of this Note in respect thereof. 

Upon the occurrence and during the continuance of any one or more of the Events of Default, all Obligations under the Credit Agreement, as
evidenced by this Note, shall become, or may be declared to be, immediately due and payable, all as provided in the Credit Agreement. 
 All
parties now and hereafter liable with respect to this Note, whether as maker, principal, surety, guarantor, endorser or otherwise, hereby waive presentment, demand, protest and all other notices of any kind. 

Unless otherwise defined herein, terms defined in the Credit Agreement and used herein shall have the meanings given to them in the Credit
Agreement. 

 NOTWITHSTANDING ANYTHING TO THE CONTRARY CONTAINED HEREIN OR IN THE CREDIT AGREEMENT, THIS
NOTE MAY NOT BE TRANSFERRED EXCEPT PURSUANT TO AND IN ACCORDANCE WITH THE CREDIT AGREEMENT. 
 THIS NOTE SHALL BE GOVERNED BY, AND
CONSTRUED AND INTERPRETED IN ACCORDANCE WITH, THE LAW OF THE STATE OF NEW YORK. 
 [Remainder of Page Intentionally Left Blank]

 
			
	BORROWER:
	
	
[                          
              ],
 a
[                                        
]

		
	By:	 	  

		 	Name:
		 	Title:

 SCHEDULE 

TERM NOTE 
  

							
	 Date
	 	 Type and Amount of Term Loan
	 	 Amount of Principal Paid or Prepaid
	  	Unpaid Principal
Amount of Note
	      
	 		 		  	
	      
	 		 		  	
	      
	 		 		  	
	      
	 		 		  	
	      
	 		 		  	
	      
	 		 		  	
	      
	 		 		  	
	      
	 		 		  	
	      
	 		 		  	
	      
	 		 		  	
	      
	 		 		  	
	      
	 		 		  	
	      
	 		 		  	
	      
	 		 		  	
	      
	 		 		  	
	      
	 		 		  	
	      
	 		 		  	
	      
	 		 		  	
	      
	 		 		  	
	      
	 		 		  	
	      
	 		 		  	
	      
	 		 		  	

 EXHIBIT C 

FORM OF IP SECURITY AGREEMENTS 

COPYRIGHT SECURITY AGREEMENT 

WHEREAS, [                    ], a
[                    ] (herein referred to as “Grantor”), having an address at
[                    ], has adopted, used and is using the copyrights listed on the annexed
Schedule 1-A, which copyrights are registered in the United States Copyright Office (the “Copyrights”); 

WHEREAS, the Grantor has entered into a Security Agreement, dated as of
[                    ], 2013 (said Security Agreement, as it may hereafter be amended or otherwise modified from time to time being the
“Security Agreement”, the terms defined therein and not otherwise defined herein being used herein as therein defined) in favor of the Agent, for itself and the Lender party to the Credit Agreement (in such capacity, the
“Secured Party”); and 
 WHEREAS, pursuant to the Security Agreement, the Grantor has granted to Secured Party a
security interest in all right, title and interest of the Grantor in and to the Copyrights, and the registrations and recordings thereof in the United States Copyright Office or any other country or any political subdivision thereof, all whether now
or hereafter owned or licensable by the Grantor and all extensions or renewals thereof and all Copyright licenses, and all proceeds of all of the foregoing, including, without limitation, any claims by the Grantor against third parties for
infringement thereof, to secure the payment and performance of the Obligations. 
 NOW, THEREFORE, for good and valuable
consideration, receipt of which is hereby acknowledged, the Grantor does hereby further confirm, and put on the public record: 

Section 1. Grant of Security Interest in Copyright Collateral. Each Grantor, as collateral security for the prompt and
complete payment and performance when due (whether at stated maturity, by acceleration or otherwise) of the Obligations of such Grantor, hereby mortgages, pledges and hypothecates to the Agent for the benefit of the Secured Creditors, and grants to
the Agent for the benefit of the Secured Creditors a Lien on and security interest in, all of its right, title and interest in, to and under the following Collateral of such Grantor (the “Copyright Collateral”): 

(i) all of its Copyrights, including, without limitation, those referred to on Schedule 1-A hereto; 

(ii) all renewals, reversions and extensions of the foregoing; and 

(iii) all income, royalties, proceeds and liabilities at any time due or payable or asserted under and with respect to any of the foregoing,
including, without limitation, all rights to sue and recover at law or in equity for any past, present and future infringement, misappropriation, dilution, violation or other impairment thereof. 

 Section 2. Security Agreement. The security interest granted pursuant to this
Copyright Security Agreement is granted in conjunction with the security interest granted to the Agent pursuant to the Security Agreement and each Grantor hereby acknowledges and agrees that the rights and remedies of the Agent with respect to the
security interest in the Copyright Collateral made and granted hereby are more fully set forth in the Security Agreement, the terms and provisions of which are incorporated by reference herein as if fully set forth herein. In the event of any
irreconcilable conflict between the terms of this Copyright Security Agreement and the terms of the Security Agreement, the terms of the Security Agreement shall control. 

SECTION 3. Grantor Remains Liable. Each Grantor hereby agrees that, anything herein to the contrary notwithstanding, such
Grantor shall assume responsibility for the prosecution, defense, enforcement or any other necessary or desirable actions in such Grantor’s reasonable business judgment in connection with their Copyrights subject to a security interest
hereunder. 
 SECTION 4. GOVERNING LAW THIS COPYRIGHT SECURITY AGREEMENT SHALL BE GOVERNED BY THE LAWS OF THE STATE OF
NEW YORK. 
 Section 5. Counterparts. This Copyright Security Agreement may be executed in any number of counterparts and
by different parties in separate counterparts, each of which when so executed shall be deemed to be an original and all of which taken together shall constitute one and the same agreement. Signature pages may be detached from multiple separate
counterparts and attached to a single counterpart. Delivery of a signature page of this Copyright Security Agreement by telecopy or other electronic means shall be effective as delivery of a manually executed counterpart of such Copyright Security
Agreement. 
 [SIGNATURE PAGES FOLLOW] 

 IN WITNESS WHEREOF, the undersigned Grantor has duly executed or caused this Copyright
Security Agreement to be duly executed as of the date first set forth above. 
  

			
	[                    ]
		
	By:	 	  

		 	Name:
		 	Title:

 Schedule 1-A to the COPYRIGHT SECURITY AGREEMENT

  

					
	 Copyright
	 	 Registration Date
	 	 Registration No.

	      
	 		 	
	      
	 		 	
	      
	 		 	
	      
	 		 	

 PATENT SECURITY AGREEMENT 

WHEREAS, [                    ], a
[                    ] (herein referred to as “Grantor”), having an address at
[                    ], owns the letters patent and/or applications for letters patent of the United States of America more particularly described on
Schedule 1-A annexed hereto as part hereof (the “Patents”); 

WHEREAS, the Grantor has entered into a Security Agreement, dated as of
[                    ], 2013 (said Security Agreement, as it may hereafter be amended or otherwise modified from time to time being the
“Security Agreement”, the terms defined therein and not otherwise defined herein being used herein as therein defined) in favor of the Agent, for itself and the Lender party to the Credit Agreement (in such capacity, the
“Secured Party”); and 
 WHEREAS, pursuant to the Security Agreement, the Grantor has granted to Secured Party a
security interest in all right, title and interest of Grantor in and to the Patents, together with all registrations and recordings thereof, including, without limitation, applications, registrations and recordings in the United States Patent and
Trademark Office or in any similar office or agency of the United States, any State thereof or any other country or any political subdivision thereof, all whether now or hereafter owned or licensable by Grantor, and all reissues, divisions,
continuations, continuations-in-part, term restorations or extensions thereof, all Patent licenses and all proceeds of all of the foregoing, including, without
limitation, any claims by Grantor against third parties for infringement thereof for the full term of the Patents, to secure the prompt payment and performance of the Obligations. 

NOW, THEREFORE, for good and valuable consideration, receipt of which is hereby acknowledged, the Grantor does hereby further confirm,
and put on the public record, its grant to Secured Party of a security interest in and mortgage on the Collateral to secure the prompt payment and performance of the Obligations. 

Section 1. Grant of Security Interest in Patents 

Each Grantor hereby grants to the Agent a security interest and continuing lien on all of such Grantor’s right, title and interest in, to
and under the following, in each case whether owned or existing or hereafter acquired or arising and wherever located (collectively, the “Patent Collateral”): all United States and foreign patents and certificates of invention, or
similar industrial property rights, including, but not limited to each patent referred to in Schedule 1-A hereto (as such schedule may be amended or supplemented from time to time), and with respect to any and all of the foregoing,
(i) all applications therefor including the patent applications referred to in Schedule 1-A hereto (as such schedule may be amended or supplemented from time to time), (ii) all reissues, divisions, continuations, continuations-in-part,
extensions, renewals, and reexaminations thereof, (iii) all rights corresponding thereto throughout the world, (iv) all inventions and improvements described therein, (v) all rights to sue for past, present and future infringements
thereof, (vi) all licenses, claims, damages, and proceeds of suit arising therefrom, and (vii) all proceeds, payments and rights to payments arising out of the sale, lease, license, assignment, or other disposition thereof. 

 Section 2. Security Agreement 

The security interests granted pursuant to this Patent Security Agreement are granted in conjunction with the security interests granted to
the Agent pursuant to the Security Agreement and each Grantor hereby acknowledges and affirms that the rights and remedies of the Agent with respect to the security interest in the Patent Collateral made and granted hereby are supplemental of, and
more fully set forth in, the Security Agreement, the terms and provisions of which are incorporated by reference herein as if fully set forth herein. In the event of any irreconcilable conflict between the terms of this Patent Security Agreement and
the terms of the Security Agreement, the terms of the Security Agreement shall control. 
 Section 3. Grantor Remains Liable.
Each Grantor hereby agrees that, anything herein to the contrary notwithstanding, such Grantor shall assume responsibility for the prosecution, defense, enforcement or any other necessary or desirable actions in such Grantor’s reasonable
business judgment in connection with their Patents subject to a security interest hereunder. 
 Section 4. GOVERNING LAW 

THIS PATENT SECURITY AGREEMENT SHALL BE GOVERNED BY THE LAWS OF THE STATE OF NEW YORK. 

Section 5. Counterparts.  

This Patent Security Agreement may be executed in counterparts, each of which shall constitute an original, but all of which when taken
together shall constitute a single contract. This Patent Security Agreement shall become effective when the Agent has received counterparts bearing the signatures of all parties hereto. Delivery of a signature page of this Patent Security Agreement
by telecopy or other electronic means shall be effective as delivery of a manually executed counterpart of such Patent Security Agreement. 

[SIGNATURE PAGE FOLLOWS] 

 IN WITNESS WHEREOF, the undersigned Grantor has duly executed or caused this Patent
Security Agreement to be duly executed as of the date first set forth above. 
  

			
	[                    ]
		
	By:	 	  

		 	Name:
		 	Title:

 Schedule 1-A to the PATENT SECURITY AGREEMENT 

 

					
	 Title
	  	 Date Filed

or Granted
	  	 Serial No. or

Patent No.

	     	  		  	
	     	  		  	
	     	  		  	
	     	  		  	

 TRADEMARK SECURITY AGREEMENT 

WHEREAS, [                    ], a
[                    ] (herein referred to as “Grantor”), having an address at
[                    ], (1) has adopted, used and is using, or (2) has intended to use and filed an application indicating that intention,
but has not yet filed an allegation of use under Section l(c) or l(d) of the Trademark Act, or (3) has filed an application based on an intention to use and has since used and has filed an allegation of use under Section l(c) or l(d)
of the Trademark Act, the trademarks, trade names, trade styles and service marks listed on the annexed Schedule 1-A, which trademarks, trade names, trade styles and service marks are registered, or for
which applications for registration have been filed in the United States Patent and Trademark Office (the “Trademarks”); and 

WHEREAS, the Grantor has entered into a Security Agreement, dated as of
[                    ], 2013 (said Security Agreement, as it may hereafter be amended or otherwise modified from time to time being the
“Security Agreement”, the terms defined therein and not otherwise defined herein being used herein as therein defined) in favor of the Agent, for itself and the Lender party to the Credit Agreement (in such capacity, the
“Secured Party”); and 
 WHEREAS, pursuant to the Security Agreement, the Grantor has granted to Secured Party a
security interest in all right, title and interest of the Grantor in and to the Trademarks, together with all prints and labels on which said Trademarks have appeared or appear, designs and general intangibles of like nature, now existing or
hereafter adopted or acquired, and the goodwill of the business symbolized by the Trademarks and the applications, registrations and recordings in the United States Patent and Trademark Office or in any similar office or agency of the United States
of America, any State thereof, or any other country or any political subdivision thereof, all whether now or hereafter owned or licensable by Grantor, and all reissues, extensions or renewals thereof, all Trademark licenses and all proceeds of all
of the foregoing, including, without limitation, any claims by Grantor against third parties for infringement thereof, to secure the payment and performance of the Obligations. 

NOW, THEREFORE, for good and valuable consideration, receipt of which is hereby acknowledged, the Grantor does hereby further confirm,
and put on the public record: 
 Section 1. Grant of Security Interest in Trademarks. 

Each Grantor hereby grants to the Agent a security interest and continuing lien on all of such Grantor’s right, title and interest in, to
and under the following, in each case whether owned or existing or hereafter acquired or arising and wherever located (collectively, the “Trademark Collateral”): 

(i) all United States, State and foreign trademarks, service marks, certification marks, collective marks, trade names,
corporate names, d/b/as, business names, fictitious business names, Internet domain names, trade styles, 

 
logos, other source or business identifiers, designs and general intangibles of a like nature and, with respect to any and all of the foregoing: (i) all registrations and applications
therefor including, but not limited to, the registrations and applications referred to in Schedule 1-A hereto (as such schedule may be amended or supplemented from time to time), 

(ii) the goodwill of the business symbolized thereby, 

(iii) all rights corresponding thereto throughout the world, 

(iv) all rights to sue for past, present and future infringement or dilution thereof or for any injury to goodwill, 

(v) all licenses, claims, damages, and proceeds of suit arising therefrom, and 

(vi) all payments and rights to payments arising out of the sale, lease, license assignment or other disposition thereof; 

provided that the security interest granted under Section 2 hereof shall not attach to, and the term “Trademark
Collateral” shall not include any applications for trademark filed in the United States Patent and Trademark Office pursuant to 15 U.S.C. § 1051 Section 1(b), only to the extent that the grant of a security interest therein would
result in the abandonment, invalidation or unenforceability of the trademarks matured from such application or rights hereunder and only until evidence of the use of such trademarks in commerce, as defined in 15 U.S.C. Section 1127, is
submitted to, and accepted by, the United States Patent and Trademark Office pursuant to 15 U.S.C. § 1051 Section 1(c) or 1(d), following which filing all such applications shall automatically become Trademark Collateral. 

Section 2. Security Agreement 

The security interests granted pursuant to this Trademark Security Agreement are granted in conjunction with the security interests granted to
the Agent pursuant to the Security Agreement and each Grantor hereby acknowledges and affirms that the rights and remedies of the Agent with respect to the security interest in the Trademark Collateral made and granted hereby are supplemental of,
and more fully set forth in, the Security Agreement, the terms and provisions of which are incorporated by reference herein as if fully set forth herein. In the event of any irreconcilable conflict between the terms of this Trademark Security
Agreement and the terms of the Security Agreement, the terms of the Security Agreement shall control. 
 Section 3. Grantor Remains
Liable. Each Grantor hereby agrees that, anything herein to the contrary notwithstanding, such Grantor shall assume responsibility for the prosecution, defense, enforcement or any other necessary or desirable actions in such Grantor’s
reasonable business judgment in connection with their Trademarks subject to a security interest hereunder. 

 Section 4. GOVERNING LAW 

THIS TRADEMARK SECURITY AGREEMENT SHALL BE GOVERNED BY THE LAWS OF THE STATE OF NEW YORK. 

Section 5. Counterparts. 

This Trademark Security Agreement may be executed in counterparts, each of which shall constitute an original, but all of which when taken
together shall constitute a single contract. This Trademark Security Agreement shall become effective when the Agent has received counterparts bearing the signatures of all parties hereto. Delivery of a signature page of this Trademark Security
Agreement by telecopy or other electronic means shall be effective as delivery of a manually executed counterpart of such Trademark Security Agreement. 

[SIGNATURE PAGE FOLLOWS] 

 IN WITNESS WHEREOF, the undersigned Grantor has duly executed or caused this Trademark
Security Agreement to be duly executed as of the date first set forth above. 
  

					
	[                     ]
		
	By:	 	  

		 	Name:
		 	Title:

 Schedule 1-A to the TRADEMARK SECURITY AGREEMENT

  

					
	 Trademark
	  	 Application or Registration Date
	  	 Application Serial

No. or Registration

No.EX-10.21

 Exhibit 10.21 

EXECUTION VERSION 

SECURITY AGREEMENT 
 DATED
AS OF OCTOBER 31, 2013 
 BY AND AMONG 

DURATA THERAPEUTICS HOLDING C.V., 

DURATA THERAPEUTICS INTERNATIONAL B.V., 

DURATA THERAPEUTICS, INC., 
 AND

 CERTAIN SUBSIDIARIES OF DURATA THERAPEUTICS, INC. PARTY HERETO 

AS GRANTORS, 
 IN FAVOR OF 

PDL BIOPHARMA, INC., 
 AS
COLLATERAL AGENT 

 TABLE OF CONTENTS 

 

							
	 	 	 	  	Page	 
			
	Section 1.	 	 Definitions.
	  	 	1	  
			
	 1.01.
	 	 Definition of Terms Used Herein Generally.
	  	 	1	  
			
	 1.02.
	 	 Definition of Certain Terms Used Herein.
	  	 	2	  
			
	 1.03.
	 	 Rules of Interpretation.
	  	 	5	  
			
	Section 2.	 	 Grant of Security Interest.
	  	 	6	  
			
	Section 3.	 	 Authorization to File Financing Statements.
	  	 	9	  
			
	Section 4.	 	 Relation to Intellectual Property Security Agreements.
	  	 	9	  
			
	Section 5.	 	 Representations and Warranties.
	  	 	9	  
			
	 5.01.
	 	 Grantors’ Legal Status.
	  	 	9	  
			
	 5.02.
	 	 Grantors’ Legal Names.
	  	 	9	  
			
	 5.03.
	 	 Grantors’ Locations.
	  	 	10	  
			
	 5.04.
	 	 Representations in the Credit Agreement.
	  	 	10	  
			
	 5.05.
	 	 Title to Collateral.
	  	 	10	  
			
	 5.06.
	 	 Nature of Collateral.
	  	 	10	  
			
	 5.07.
	 	 Compliance with Laws.
	  	 	11	  
			
	 5.08.
	 	 Validity of Security Interest.
	  	 	11	  
			
	 5.09.
	 	 Perfection Certificate; Intellectual Property Filings.
	  	 	11	  
			
	 5.10.
	 	 Investment Property.
	  	 	11	  
			
	 5.11.
	 	 Receivables.
	  	 	12	  
			
	 5.12.
	 	 Accounts.
	  	 	12	  
			
	 5.13.
	 	 Equipment and Inventory.
	  	 	12	  
			
	Section 6.	 	 Covenants.
	  	 	12	  
			
	 6.01.
	 	 Grantors’ Legal Status.
	  	 	12	  
			
	 6.02.
	 	 Grantors’ Names.
	  	 	12	  
			
	 6.03.
	 	 Grantors’ Organizational Numbers.
	  	 	12	  
			
	 6.04.
	 	 Locations.
	  	 	12	  
			
	 6.05.
	 	 Reserved.
	  	 	13	  
			
	 6.06.
	 	 Promissory Notes and Tangible Chattel Paper.
	  	 	13	  
			
	 6.07.
	 	 Deposit Accounts.
	  	 	13	  
			
	 6.08.
	 	 Investment Property.
	  	 	13	  
			
	 6.09.
	 	 Reserved.
	  	 	16	  
			
	 6.10.
	 	 Electronic Chattel Paper and Transferable Records.
	  	 	16	  

  
 - i - 

 TABLE OF CONTENTS 

(continued) 
  

							
	 	 	 	  	Page	 
			
	 6.11.
	 	 Letter-of-Credit Rights.
	  	 	16	  
			
	 6.12.
	 	 Commercial Tort Claims.
	  	 	17	  
			
	 6.13.
	 	 Intellectual Property.
	  	 	17	  
			
	 6.14.
	 	 Maintenance of Collateral; Compliance with Laws.
	  	 	17	  
			
	 6.15.
	 	 Dispositions of Collateral.
	  	 	17	  
			
	 6.16.
	 	 Maintenance of Insurance.
	  	 	17	  
			
	 6.17.
	 	 Periodic Certification.
	  	 	17	  
			
	 6.18.
	 	 Other Actions as to any and all Collateral.
	  	 	17	  
			
	Section 7.	 	 Reserved.
	  	 	18	  
			
	Section 8.	 	 Collateral Protection Expenses; Preservation of Collateral.
	  	 	18	  
			
	 8.01.
	 	 Expenses Incurred by the Agent.
	  	 	18	  
			
	 8.02.
	 	 Agent’s Obligations and Duties.
	  	 	18	  
			
	 8.03.
	 	 Duties as to Pledged Securities.
	  	 	20	  
			
	Section 9.	 	 Securities and Deposits.
	  	 	21	  
			
	Section 10.	 	 Notification to Account Debtors and Other Persons Obligated on Collateral.
	  	 	21	  
			
	Section 11.	 	 Power of Attorney.
	  	 	22	  
			
	 11.01.
	 	 Appointment and Powers of Agent.
	  	 	22	  
			
	 11.02.
	 	 Failure of Grantor to Perform.
	  	 	23	  
			
	 11.03.
	 	 Expenses of Attorney-in-Fact.
	  	 	23	  
			
	 11.04.
	 	 Ratification by Grantor.
	  	 	23	  
			
	 11.05.
	 	 No Duty on Agent.
	  	 	23	  
			
	Section 12.	 	 Remedies.
	  	 	24	  
			
	 12.01.
	 	 Default.
	  	 	24	  
			
	 12.02.
	 	 Remedies Upon Default.
	  	 	24	  
			
	 12.03.
	 	 Grant of License to Use Intellectual Property.
	  	 	26	  
			
	 12.04.
	 	 Waivers by Grantors.
	  	 	26	  
			
	 12.05.
	 	 Application of Proceeds.
	  	 	26	  
			
	 12.06.
	 	 Surplus, Deficiency.
	  	 	27	  
			
	 12.07.
	 	 Information Related to the Collateral.
	  	 	27	  
			
	 12.08.
	 	 Sale Exempt from Registration.
	  	 	28	  
			
	 12.09.
	 	 Rights and Remedies Cumulative.
	  	 	28	  
			
	 12.10.
	 	 No Direct Enforcement by Secured Creditors.
	  	 	29	  

 TABLE OF CONTENTS 

(continued) 
  

							
	 	 	 	  	Page	 
			
	Section 13.	 	 Standards for Exercising Remedies.
	  	 	29	  
			
	 13.01.
	 	 Commercially Reasonable Manner.
	  	 	29	  
			
	 13.02.
	 	 Standard of Care.
	  	 	30	  
			
	Section 14.	 	 Waivers by Grantor; Obligations Absolute.
	  	 	30	  
			
	 14.01.
	 	 Specific Waivers.
	  	 	30	  
			
	 14.02.
	 	 Obligations Absolute.
	  	 	30	  
			
	Section 15.	 	 Marshalling.
	  	 	31	  
			
	Section 16.	 	 Interest.
	  	 	31	  
			
	Section 17.	 	 Reinstatement.
	  	 	31	  
			
	Section 18.	 	 Miscellaneous.
	  	 	31	  
			
	 18.01.
	 	 Notices.
	  	 	31	  
			
	 18.02.
	 	 GOVERNING LAW; CONSENT TO JURISDICTION; SERVICE OF PROCESS.
	  	 	31	  
			
	 18.03.
	 	 WAIVER OF JURY TRIAL, ETC.
	  	 	32	  
			
	 18.04.
	 	 Counterparts.
	  	 	32	  
			
	 18.05.
	 	 Headings.
	  	 	32	  
			
	 18.06.
	 	 No Strict Construction.
	  	 	33	  
			
	 18.07.
	 	 Severability.
	  	 	33	  
			
	 18.08.
	 	 Survival of Agreement.
	  	 	33	  
			
	 18.09.
	 	 Fees and Expenses; Indemnification.
	  	 	33	  
			
	 18.10.
	 	 Binding Effect; Several Agreement.
	  	 	34	  
			
	 18.11.
	 	 Waivers; Amendment.
	  	 	34	  
			
	 18.12.
	 	 Limitation of Liability.
	  	 	34	  
			
	 18.13.
	 	 Integration.
	  	 	35	  
			
	 18.14.
	 	 Acknowledgments.
	  	 	35	  
			
	 18.15.
	 	 Additional Grantors.
	  	 	35	  
			
	 18.16.
	 	 Releases.
	  	 	35	  
			
	 18.17.
	 	 Intercompany Debt.
	  	 	36	  

 TABLE OF CONTENTS 

(continued) 
  

					
	 	 	 	  	Page
		
	 EXHIBITS
	  	
			
	 A
	 	Form of Copyright Security Agreement	  	
	 B
	 	Form of Patent Security Agreement	  	
	 C
	 	Form of Trademark Security Agreement	  	
	 D
	 	Form of Control Agreement in Respect of Uncertificated Securities	  	
		
	 ANNEXES
	  	
			
	 I
	 	Form of Joinder Agreement	  	

 SECURITY AGREEMENT (the “Agreement”), dated as of October 31, 2013, by
DURATA THERAPEUTICS HOLDING C.V., a limited partnership organized under the laws of the Netherlands (“Durata C.V.”), DURATA THERAPEUTICS INTERNATIONAL B.V., a private company with limited liability incorporated under the laws of the
Netherlands having its official seat in Amsterdam, the Netherlands, and which is registered with the Dutch trade register under number 55527221 (“Durata B.V.”), DURATA THERAPEUTICS, INC., a Delaware corporation
(“Parent”), Durata Therapeutics U.S. Limited, a Delaware corporation (“Durata U.S.”) and certain other subsidiaries of Parent that are party hereto (Durata U.S. together with such other subsidiaries, the
“Subsidiaries” and together with Durata C.V., Durata B.V., Parent, and any other entity that may become a party hereto as a grantor as provided herein, each a “Grantor” and collectively, jointly and severally, the
“Grantors”), in favor of PDL BIOPHARMA, INC., as Collateral Agent (in such capacity, the “Agent”) under the Credit Agreement, dated as of the date hereof (as amended, amended and restated, supplemented or otherwise
modified from time to time, the “Credit Agreement”) by and among Durata C.V. and Durata B.V., as borrowers (in such capacity, the “Borrowers”), Parent, the Subsidiaries, PDL BIOPHARMA, INC., as lender (in such
capacity, the “Lender”), and the Agent. 
 W I T N E S S E T
H: 
 WHEREAS, pursuant to the Credit Agreement, the Lender has agreed to make certain extensions of credit to the Borrowers upon the
terms and conditions set forth therein; and 
 WHEREAS, it is a condition precedent to the obligations of the Lender to make its extensions
of credit to the Borrowers under the Credit Agreement that the Grantors shall have executed and delivered this Agreement to the Agent. 

NOW, THEREFORE, in consideration of the premises set forth above and for other good and valuable consideration, the receipt and sufficiency of
which are hereby acknowledged, the parties hereto agree as follows: 
 Section 1. DEFINITIONS. 

1.01. Definition of Terms Used Herein Generally. Except as otherwise provided herein, all capitalized terms used herein (including in
the preamble hereto) but not defined herein shall have the meanings ascribed to such terms in the Credit Agreement. Notwithstanding the foregoing, except as specifically provided herein, all terms used herein and defined in the NYUCC shall have the
same definitions herein as ascribed to such terms therein as of the date hereof; provided, however, that if a term is defined in Article 9 of the NYUCC differently than in another Article of the NYUCC, the term has the meaning
ascribed to such term in Article 9 of the NYUCC as of the date hereof. 

 1.02. Definition of Certain Terms Used Herein. As used herein, the following terms shall
have the following meanings: 
 “Additional Grantor”: as defined in Annex I hereto. 

“Agent”: as defined in the preamble. 

“Agreement”: this Security Agreement, as the same may be amended, supplemented, replaced or otherwise modified from time to
time. 
 “Bankruptcy Code”: Title 11 of the United States Code (11 U.S.C. Section 101 et seq.), or any successor
statute, as amended. 
 “Borrowers”: as defined in the preamble. Any references herein to “each”,”
“either” or “such” Borrower or to the “applicable” Borrower, or to “the Borrower” shall mean and refer to such Borrower as the context requires. 

“Collateral”: as defined in Section 2. 

“Copyright Office”: the United States Copyright Office. 

“Copyright Security Agreement”: a supplement to this Agreement, executed by one or more Grantors in favor of the Agent,
substantially in the form of Exhibit A hereto. 
 “Credit Agreement”: as defined in the preamble. 

“Durata B.V.”: as defined in the preamble. 

“Durata C.V.”: as defined in the preamble. 

“Durata U.S.”: as defined in the preamble. 

“Event”: as defined in Section 8.03. 

“Foreign Collateral”: as defined in Section 2 

“Foreign Guarantor Obligations”: the obligations owed by any Guarantor under the Foreign Guarantee Agreement. 

“Foreign Guarantee Agreement”: that certain Guarantee Agreement, if any, to be entered into by and among any foreign
Guarantor time to time and the Agent, as amended, modified and in effect from time to time. 
 “Foreign Obligations”: the
Borrower Obligations and the Foreign Guarantor Obligations. 
 “General Intangibles”: all “general intangibles”
as such term is defined in Section 9-102(42) of the NYUCC as in effect on the date hereof and, in any event, including, without limitation, with respect to any Grantor, all contracts, agreements, instruments and

  
 2 

 
indentures and all licenses and permits issued by Governmental Authorities in any form, and portions thereof, to which such Grantor is a party or under which such Grantor has any right, title or
interest or to which such Grantor or any property of such Grantor is subject, as the same may from time to time be amended, supplemented, replaced or otherwise modified, including, without limitation, (i) all rights of such Grantor to receive
moneys due and to become due to it thereunder or in connection therewith; (ii) all rights of such Grantor to receive proceeds of any insurance, indemnity, warranty or guaranty with respect thereto; (iii) all rights of such Grantor to
damages arising thereunder; (iv) all rights of such Grantor to receive any tax refunds; and (v) all rights of such Grantor to terminate and to perform, to compel performance and to exercise all remedies thereunder. 

“Grantor(s)”: as defined in the preamble. 

“Intellectual Property Security Agreement”: each Copyright Security Agreement, Patent Security Agreement and Trademark
Security Agreement. 
 “Intercompany Debt”: as defined in Section 18.17. 

“Investment Property”: the collective reference to (i) all “investment property” as such term is defined in
Section 9-102(48) of the NYUCC on the date hereof including, without limitation, all certificated securities and uncertificated securities, all security entitlements, and all securities accounts, and (ii) security entitlements, in the case
of any United States Treasury book-entry securities, as defined in 31 C.F.R. § 357.2, or, in the case of any United States federal agency book-entry securities, as defined in the corresponding United States federal regulations
governing such book-entry securities; and (iii) whether or not constituting “investment property” as so defined, all Pledged Notes, all Pledged Stock and all Pledged Security Entitlements. 

“Issuers”: the collective reference to each issuer of a Pledged Security. 

“Joinder Agreement”: each agreement, in the form of Annex I hereto, executed and delivered by each Person that shall
become an Additional Grantor hereunder. 
 “Lease”: any lease of personal property under which any Grantor is the lessee.

 “Lender”: as defined in the preamble. 

“NYUCC”: the Uniform Commercial Code as in effect in the State of New York from time to time. 

“Parent”: as defined in the preamble. 

“Patent Security Agreement”: a supplement to this Agreement, executed by one or more Grantors in favor of Agent,
substantially in the form of Exhibit B hereto. 
 “Perfection Certificate”: shall mean that certain Perfection
Certificate dated as of the date hereof executed by the Borrowers in favor of the Agent, as updated by the 

  
 3 

 
Borrower or any other Grantor from time to time after the Closing Date (including pursuant to a Perfection Supplement), and as supplemented from time to time with Annex I-A to each Joinder
Agreement executed and delivered to the Agent by each Person that shall become an Additional Grantor hereunder. 
 “Perfection
Supplement”: shall have the meaning assigned to such term in Section 6.17. 
 “Pledged Debt
Securities”: the debt securities owned by any Grantor and set forth in the Perfection Certificate, together with any other certificates, options, rights or security entitlements of any nature whatsoever in respect of the debt securities of
any Person that may be issued or granted to, or held by, any Grantor while this Agreement is in effect. 
 “Pledged Notes”:
all promissory notes owned by any Grantor and set forth in the Perfection Certificate, all intercompany notes at any time issued to any Grantor and all other promissory notes issued to or held by any Grantor. 

“Pledged Securities”: the collective reference to the Pledged Debt Securities, the Pledged Notes and the Pledged Stock. 

“Pledged Stock”: the shares of capital stock or other equity interests owned at any time or from time to time by any Grantor,
including, without limitation, in the case of the Borrowers, all shares of capital stock, or membership interests, as applicable, in all Grantors that are Subsidiaries of any Borrower, together with any other shares, stock certificates, options,
rights or security entitlements of any nature whatsoever in respect of the capital stock or other equity interests of any Person that may be issued or granted to, or held by, any Grantor while this Agreement is in effect. 

“Proceeds”: all “proceeds” as such term is defined in Section 9-102(64) of the NYUCC in effect on the date
hereof and, in any event, shall include, without limitation, all dividends or other income from the Pledged Securities, collections thereon or distributions or payments with respect thereto. 

“Property”: any right or interest in or to property of any kind whatsoever, whether real, personal or mixed and whether
tangible or intangible, including capital stock or other equity interests. 
 “PTO”: the United States Patent and Trademark
Office. 
 “Receivable”: any right to payment on account of any obligation that could create any right to receive money,
whether or not such right is evidenced by an instrument or chattel paper and whether or not it has been earned by performance (including, without limitation, any account or payment intangible). 

  
 4 

 “Secured Creditors”: the Agent, in both its capacities as administrative agent
under the Credit Agreement and collateral agent under the Collateral Documents, and the Lender under the Credit Agreement, and each of their successors and assigns. 

“Securities Act”: the Securities Act of 1933, as amended. 

“Security Documents”: this Agreement (as supplemented from time to time by any Joinder Agreement), any Subsidiary Guaranty,
the Intellectual Property Security Agreements, all deposit account control agreements and all other pledge or security agreements, assignments or other similar agreements or instruments executed and delivered by any Grantor pursuant to
Section 4.1.1, Section 6.7, Section 6.11 or Section 7.12 of the Credit Agreement or otherwise in connection with the transactions contemplated thereby, in each case as amended, modified, restated or
supplemented from time to time. 
 “Security Interest”: the security interest granted pursuant to Section 2, as
well as all other security interests created or assigned as additional security for the U.S. Guarantor Obligations or the Foreign Obligations, as applicable, pursuant to the provisions of this Agreement. 

“Subsidiaries”: as defined in the preamble. 

“Trademark Security Agreement”: a supplement to this Agreement, executed by the Grantor in favor of Agent, substantially in
the form of Exhibit C hereto. 
 “U.S. Guarantee Agreement”: that certain Guarantee Agreement of even date
herewith, by and among the Parent, Vicuron, Durata U.S., any other parties party thereto from time to time and the Agent, as amended, modified and in effect from time to time. 

“U.S. Guarantor Collateral”: as defined in Section 2 

“U.S. Guarantor Obligations”: the “Guaranteed Obligations” as defined in the U.S. Guarantee Agreement. 

“UCC”: the Uniform Commercial Code as in effect in any jurisdiction (except as otherwise contemplated in
Section 6.18). References to particular sections of Article 9 of the UCC shall be, unless otherwise indicated, references to revised Article 9 of the UCC adopted and effective in certain jurisdictions on or after July 1, 2001. 

“Vicuron”: Vicuron Pharmaceuticals, Inc., a Delaware corporation. 

1.03. Rules of Interpretation. The rules of interpretation specified in Section 1.2 of Credit Agreement shall be applicable
to this Agreement. References to “Sections,” “Exhibits” and “Schedules” shall be to Sections, Exhibits and Schedules, respectively, of this Agreement unless otherwise specifically provided. Any of the terms defined in
this Section 1 may, unless the context otherwise requires, be used in the singular or the plural depending on the reference. All references to statutes and related regulations shall include (unless otherwise specifically provided herein)
any amendments of same and any successor statutes and regulations. 

  
 5 

 Section 2. GRANT OF SECURITY
INTEREST. 
 Each of Parent, Vicuron, Durata U.S. and each other Grantor that is organized in the United States or a state or
territory thereof, hereby grants to the Agent, for the ratable benefit of the Secured Creditors, a security interest in, and mortgage on, all of the Property now owned or at any time hereafter acquired by such Grantor or in which such Grantor now
has, or at any time in the future may acquire, any right, title or interest (collectively, the “U.S. Guarantor Collateral”), as collateral security for the prompt and complete payment and performance when due (whether at the stated
maturity, by acceleration or otherwise) of the U.S. Guarantor Obligations owed by such Grantor, including, without limitation: 
 a. all
Accounts; 
 b. all Chattel Paper, including tangible chattel paper and electronic chattel paper; 

c. all Goods; 
 d. all
Documents; 
 e. all Equipment; 

f. all Fixtures; 
 g. all
General Intangibles, including all Payment Intangibles; 
 h. all Instruments; 

i. all Intellectual Property; 

j. all Inventory; 
 k. all
Investment Property; 
 l. all Leases; 

m. all Letter-of-Credit Rights; 

n. all money; 
 o. all
Supporting Obligations; 
 p. all tort claims, including Commercial Tort Claims; 

  
 6 

 q. all Deposit Accounts, all claims now or hereafter arising therefrom, all funds now or
hereafter held therein, all amounts now or hereafter credited thereto and all certificates and instruments, if any, from time to time representing or evidencing such bank accounts; 

r. all other property not otherwise described above; 

s. all books and records pertaining to the U.S. Guarantor Collateral; and 

t. to the extent not otherwise included, all Proceeds and products of any and all of the foregoing and all collateral security and guarantees
given by any Person with respect to any of the foregoing. 
 Each of the Borrowers and each other Grantor that is organized outside of the
United States or a state or territory thereof, hereby grants to the Agent, for the ratable benefit of the Secured Creditors, a security interest in, and mortgage on, to the extent possible under the laws of its location, all of the Property now
owned or at any time hereafter acquired by such Grantor or in which such Grantor now has, or at any time in the future may acquire, any right, title or interest (collectively, the “Foreign Collateral”; and together with the U.S.
Guarantor Collateral, the “Collateral”), as collateral security for the prompt and complete payment and performance when due (whether at the stated maturity, by acceleration or otherwise) of the Foreign Obligations owed by such
Grantor, including, without limitation: 
 a. all Accounts; 

b. all Chattel Paper, including tangible chattel paper and electronic chattel paper; 

c. all Goods; 
 d. all
Documents; 
 e. all Equipment; 

f. all Fixtures; 
 g. all
General Intangibles, including all Payment Intangibles; 
 h. all Instruments; 

i. all Intellectual Property; 

j. all Inventory; 
 k. all
Investment Property; 
 l. all Leases; 

m. all Letter-of-Credit Rights; 

  
 7 

 n. all money; 

o. all Supporting Obligations; 

p. all tort claims, including Commercial Tort Claims; 

q. all Deposit Accounts, all claims now or hereafter arising therefrom, all funds now or hereafter held therein, all amounts now or hereafter
credited thereto and all certificates and instruments, if any, from time to time representing or evidencing such bank accounts; 
 r. all
other property not otherwise described above; 
 s. all books and records pertaining to the Foreign Collateral; and 

t. to the extent not otherwise included, all Proceeds and products of any and all of the foregoing and all collateral security and guarantees
given by any Person with respect to any of the foregoing. 
 Notwithstanding anything herein to the contrary, in no event shall the
Collateral include or the security interest granted under this Section 2 attach to (A) any lease, license, contract or agreement to which any Grantor is a party if and for so long as the grant of such security interest shall
constitute or result in (i) the invalidation or unenforceability of any right, title or interest of any Grantor therein or (ii) a breach or termination pursuant to the terms of, or a default under, any such lease, license, contract or
agreement (other than to the extent that any such term would be rendered ineffective pursuant to Sections 9-406, 9-407, 9-408 or 9-409 of the UCC (or any successor provision or provisions) of any relevant jurisdiction or any other Applicable Law
(including the Bankruptcy Code) or principles of equity); provided, however that the Collateral shall include and such security interest shall attach immediately at such time as the condition causing such invalidation or
unenforceability shall be remedied and to the extent severable, shall attach immediately to any portion of such lease, license, contract or agreement that does not result in any of the consequences specified in clause (i) or (ii) above or
(B) any trademark applications filed in the United States Patent and Trademark Office on the basis of such Grantor’s “intent-to-use” such trademark to the extent that granting a security interest in such trademark application
prior to such filing would result in the unenforceability, invalidation or voiding of such trademark application, unless and until use of the trademark has been filed with and accepted by the United States Patent and Trademark Office pursuant to
Section 1(c) or Section 1(d) of the Lanham Act (15 U.S.C. 1051, et seq.), whereupon such trademark application will be deemed automatically included in the Collateral, (C) any equipment financed by a third party and products and
proceeds thereof subject to a lien permitted by Section 7.2(d) of the Credit Agreement to the extent that the security interest is prohibited by the terms of the agreement governing such financing, (D) any collateral securing letter
of credit or credit card reimbursement obligations or hedging obligations permitted under the Credit Agreement, or (E) the Connecticut Assets. 

  
 8 

 Section 3. AUTHORIZATION TO FILE
FINANCING STATEMENTS. Each Grantor hereby irrevocably authorizes the Agent at any time and from time to time to file in any applicable jurisdiction in which the UCC has been adopted any initial financing statements and
amendments thereto that (a) indicate the Collateral (i) as “all assets” of such Grantor or words of similar effect, regardless of whether any particular asset comprised in the Collateral falls within the scope of Article 9
of the NYUCC or such jurisdiction, or (ii) as being of an equal or lesser scope or with greater detail, and (b) contain any other information required by part 5 of Article 9 of the UCC for the sufficiency or filing office
acceptance of any initial financing statement or amendment, including whether such Grantor is an organization, the type of organization and any organization identification number issued to such Grantor. Each Grantor agrees to furnish any such
information to the Agent promptly upon request. Each Grantor also ratifies its authorization for the Agent to have filed in any UCC jurisdiction any like initial financing statements or amendments thereto if filed prior to the date hereof. 

Section 4. RELATION TO INTELLECTUAL PROPERTY SECURITY
AGREEMENTS. Concurrently herewith the Grantor is executing and delivering to the Agent for recording in the PTO the Patent Security Agreement and the Trademark Security Agreement. As of the Closing Date the Grantors hold no Copyrights
or applications in respect thereof that are registered with the Copyright Office. The provisions of any current or any future Patent Security Agreement, Trademark Security Agreement or Copyright Security Agreement are supplemental to the provisions
of this Agreement. Nothing contained in any current or future Patent Security Agreement, Trademark Security Agreement or Copyright Security Agreement shall derogate from any of the rights or remedies of any Secured Creditor hereunder, nor shall
anything contained in any such current or future Patent Security Agreement, Trademark Security Agreement or Copyright Security Agreement be deemed to prevent or extend the time of attachment or perfection of any Security Interest in such Collateral
created hereby. 
 Section 5. Representations and Warranties. To induce the Agent and the Lender to enter into the Credit
Agreement and to induce the Lender to make its extensions of credit to the Borrowers thereunder, each Grantor hereby represents and warrants to the Secured Creditors that: 

5.01. Grantors’ Legal Status. As of the Closing Date and thereafter, subject to permitted modifications in accordance with
Sections 6.01, 6.02 and 6.03, (a) such Grantor is an organization as set forth in the Perfection Certificate; (b) such organization is of the type and is organized in the jurisdiction set forth in the Perfection Certificate; and
(c) the Perfection Certificate sets forth such Grantor’s correct organizational identification number or accurately states that such Grantor has none. 

5.02. Grantors’ Legal Names. As of the Closing Date and thereafter, subject to permitted modifications in accordance with
Sections 6.01, 6.02 and 6.03, such Grantor’s exact legal name is that set forth in the Perfection Certificate and as of the date hereof on the signature page hereof. 

  
 9 

 5.03. Grantors’ Locations. As of the Closing Date and thereafter, subject to
permitted modifications in accordance with Sections 6.01, 6.02 and 6.03, the Perfection Certificate sets forth such Grantor’s place of business or (if it has more than one place of business) its chief executive office, as well as its
mailing address if different from either. 
 5.04. Representations in the Credit Agreement. The representations and warranties set
forth in Section 5 of the Credit Agreement and as otherwise made by such Grantor in each other Loan Document to which such Grantor is a party, each of which is hereby incorporated herein by reference, are true and correct in all material
respects as of the date hereof, and the Secured Creditors shall be entitled to rely on each of them as if they were fully set forth herein. 

5.05. Title to Collateral. The Collateral of such Grantor is owned by such Grantor free and clear of any Lien, except for Liens
expressly permitted pursuant to the Credit Agreement. Such Grantor has not filed or consented to the filing of (a) any financing statement or analogous document under the UCC or any other Applicable Laws covering any of its Collateral,
(b) any assignment (other than pursuant to a disposition expressly permitted by the Credit Agreement) in which such Grantor assigns any Collateral or any security agreement or similar instrument covering any Collateral with the PTO or the
Copyright Office or (c) any assignment (other than pursuant to a disposition expressly permitted by the Credit Agreement) in which such Grantor assigns any Collateral or any security agreement or similar instrument covering any Collateral with
any foreign governmental, municipal or other office, which financing statement or analogous document, assignment, security agreement or similar instrument is still in effect, except, in each case, with respect to Liens expressly permitted pursuant
to the Credit Agreement. 
 5.06. Nature of Collateral. None of the Collateral of such Grantor constitutes, or is the proceeds of,
farm products and none of the Collateral has been purchased or will be used by such Grantor primarily for personal, family or household purposes, and as of the Closing Date, except as indicated in the Perfection Certificate: 

(a) none of the account debtors or other persons obligated on any of the Collateral of such Grantor is a Governmental Authority subject to
the Federal Assignment of Claims Act or like federal, state or local statute or rule in respect of such Collateral; 
 (b) such Grantor
holds no Commercial Tort Claims that it has asserted against any other Person; 
 (c) such Grantor has no deposit accounts or other bank
accounts; 
 (d) such Grantor owns no motor vehicles; 

(e) such Grantor has no securities accounts or securities entitlements or commodities accounts or commodities contracts; 

(f) such Grantor holds no interest in, title to or power to transfer, any patents, trademarks, copyrights, inbound licenses or other
intellectual property. 

  
 10 

 5.07. Compliance with Laws. Such Grantor has at all times operated its business in
compliance with Applicable Law, except as could not reasonably be expected to have a Material Adverse Effect. 
 5.08. Validity of
Security Interest. (a) The Security Interest granted by each Grantor constitutes a legal and valid security interest in all of the Collateral of such Grantor securing the payment and performance of the U.S. Guarantor Obligations or Foreign
Obligations, as applicable, and (b) upon the filing of financing statements describing the Collateral in the offices listed on the Perfection Certificate, the recording in the PTO of the Patent Security Agreement and Trademark Security
Agreement, and the taking of the applicable actions in respect of perfection contemplated by this Agreement, in respect of Collateral, the Security Interest will be valid, enforceable and perfected in all Collateral of such Grantor. The Security
Interest is and shall be prior to any other Lien on the Collateral, other than Liens expressly permitted to be prior to the Security Interest under the Credit Agreement. 

5.09. Perfection Certificate; Intellectual Property Filings. 

(a) All information set forth on the Perfection Certificate is, and all information set forth on each Perfection Supplement shall be, true,
accurate and complete in all material respects. 
 (b) As of the Closing Date, a fully executed Patent Security Agreement and Trademark
Security Agreement containing a description of all material Collateral of such Grantor consisting of United States registered Patents and United States registered Trademarks (and Patents and Trademarks for which United States registration
applications are pending) have been delivered to the Agent for recording by the PTO. 
 5.10. Investment Property. 

(a) The shares of Pledged Stock pledged by such Grantor hereunder, if any, constitute all of the issued and outstanding shares of all classes
of the capital stock or other equity interests of each Issuer owned by such Grantor. 
 (b) All the shares of the Pledged Stock pledged by
such Grantor have been duly and validly issued, and are fully paid and non-assessable. 
 (c) The terms of any uncertificated limited
liability company interests and partnership interests, in any limited liability company or partnership organized under the laws of the United States or any state thereof, included in the Pledged Stock expressly provide that they are securities
governed by Article 8 of the UCC in effect from time to time in the “issuer’s jurisdiction” of each Issuer thereof (as such term is defined in the UCC in effect in such jurisdiction). 

  
 11 

 (d) Such Grantor is the record and beneficial owner of, and has good and marketable title to,
the Pledged Securities pledged by it hereunder, free of any and all Liens or options in favor of, or claims of, any other Person, except the Security Interest created by this Agreement and the other Liens (other than Permitted Liens) created in
favor of the Agent by the Security Documents. 
 5.11. Receivables. No amount payable to such Grantor in excess of $500,000 under or in
connection with any Receivable is evidenced by any instrument or tangible chattel paper which has not been delivered to the Agent. 
 5.12.
Accounts. To the extent applicable, (i) each account of such Grantor is genuine and in all respects what they purport to be and (ii) each account arises out of (A) a bona fide sale of goods sold and delivered by such Grantor
(or is in the process of being delivered) or (B) services theretofore actually rendered or to be rendered by such Grantor to the account debtor named therein. 

5.13. Equipment and Inventory. With respect to any equipment and/or inventory of such Grantor, each such Grantor has exclusive
possession and control of such equipment and inventory of such Grantor except for (i) equipment leased by such Grantor as a lessor permitted by Section 7.1(b) or (d) of the Credit Agreement, (ii) equipment or inventory in
transit with common or other carriers, (iii) Excluded Inventory or (iv) as otherwise permitted under Section 6.7 (Collateral Access Agreements) of the Credit Agreement. No inventory is held by such Grantor pursuant to
consignment, sale or return, sale on approval or similar arrangement. 
 Section 6. COVENANTS. Each Grantor covenants
and agrees with the Agent, in each case at such Grantor’s own cost and expense, as follows. 
 6.01. Grantors’ Legal
Status. Such Grantor shall not change its type of organization, jurisdiction of organization except upon not less than thirty (30) days’ prior written notice to the Agent. 

6.02. Grantors’ Names. Such Grantor shall not change its name except upon not less than thirty (30) days’ prior written
notice to the Agent. 
 6.03. Grantors’ Organizational Numbers. Without providing at least thirty (30) days’ prior
written notice to the Agent, such Grantor shall not change its organizational identification number if it has one. If such Grantor does not have an organizational identification number and later obtains one, such Grantor shall forthwith notify the
Agent of such organizational identification number promptly, but in any case, within three (3) business days, upon obtaining such identification number. 

6.04. Locations. Without providing at least thirty (30) days’ prior written notice to the Agent, such Grantor shall not
change its place of business or (if it has more than one place of business) its chief executive office and shall promptly, but in any case, within the time period required under Section 6.17, notify the Agent of any new location of
Collateral with a value in excess of $250,000 (except for Excluded Inventory and inventory in transit) owned by any Borrower or a Subsidiary thereof that is not set forth on a Perfection Certificate or Perfection Supplement. 

  
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 6.05. [Reserved]. 

6.06. Promissory Notes and Tangible Chattel Paper. If such Grantor, together with the other Grantors, shall at any time hold or acquire
any promissory notes with face amounts, that in the aggregate, exceed $500,000, such Grantor shall forthwith endorse, assign and deliver the same to the Agent, accompanied by such instruments of transfer or assignment duly executed in blank as the
Agent may from time to time specify to be held by the Agent as Collateral pursuant to this Agreement. Each Grantor shall promptly endorse, assign and deliver to the Agent any tangible chattel paper (or any other instrument (other than checks
received in the ordinary course of business) evidencing any account of such Grantor) in an aggregate amount in excess of $500,000 held by such Grantor, accompanied by such instruments of transfer or assignment duly executed in blank as the Agent may
from time to time specify to be held by the Agent as Collateral pursuant to this Agreement. 
 6.07. Deposit Accounts. For each
deposit account that such Grantor at any time opens or maintains, such Grantor shall comply with the provisions of Section 7.12 of the Credit Agreement. 

6.08. Investment Property. 

(a) If any of the Collateral shall be or become evidenced or represented by an uncertificated security, subject to applicable law for foreign
Grantors and subject to Section 6.11, such Grantor shall cause the Issuer thereof either (i) to register the Agent as the registered owner of such uncertificated security, upon original issue or registration of transfer or
(ii) to agree in writing with such Grantor and the Agent that such Issuer will comply with instructions with respect to such uncertificated security originated by the Agent without further consent of such Grantor, such agreement to be in
substantially the form of Exhibit D or such other form as the Agent shall approve in its reasonable discretion; provided, however, that if such foreign Grantor complies with foreign security documents entered into by such
foreign Grantor and the Agent with respect to a specific portion of the Collateral such foreign Grantor shall be demed to have complied with Section 6.08(a). 

(b) Subject to Section 7.12 of the Credit Agreement, if any of the Collateral shall be or become evidenced or represented by a security
entitlement, such Grantor shall cause the securities intermediary with respect to such security entitlement either (i) to identify in its records the Agent as having such security entitlement against such securities intermediary or (ii) to
agree in writing with such Grantor and the Agent that such securities intermediary will comply with entitlement orders originated by the Agent without further consent of such Grantor, such agreement to be in such form as the Agent shall approve.

  
 13 

 (c) [Reserved] 

(d) Subject to Section 7.12 of the Credit Agreement, if any of the Collateral shall be or become evidenced or represented by or held in
a securities account, such Grantor shall comply with clause (b) of this Section 6.08 with respect to all security entitlements carried in such securities account. 

(e) If such Grantor shall receive any stock or other ownership certificate (including, without limitation, any certificate representing a
stock dividend or a distribution in connection with any reclassification, increase or reduction of capital or any certificate issued in connection with any reorganization), or other certificated option or rights in respect of the capital stock or
other equity interests of any Issuer, whether in addition to, in substitution of, as a conversion of, or in exchange for, any shares of or other ownership interests in the Pledged Stock, or otherwise in respect thereof, such Grantor shall accept the
same as the agent of the Secured Creditors, hold the same in trust for the Secured Creditors and deliver the same forthwith to the Agent in the exact form received, duly endorsed by such Grantor to the Agent, if required, together with an undated
stock power covering such certificate duly executed in blank by such Grantor, to be held by the Agent, subject to the terms hereof, as additional collateral security for the U.S. Guarantor Obligations or the Foreign Obligations, as applicable. 

(f) Subject to Section 6.08(h) hereof, such Grantor shall be entitled: 

(i) to exercise in a manner not inconsistent with the terms hereof and of the Credit Agreement, the voting power with respect to the Pledged
Stock of such Grantor, and for that purpose the Agent shall (if any Pledged Stock shall be registered in the name of the Agent or its nominee) execute or cause to be executed from time to time, at the expense of such Grantor, such proxies or other
instruments in favor of such Grantor or its nominee, in such form and for such purposes as shall be reasonably required by such Grantor and shall be specified in a written request therefor, to enable it to exercise such voting power with respect to
the Pledged Stock; and 
 (ii) except as otherwise provided in paragraphs (g) and (h) of this Section 6.08, to
receive and retain for its own account any and all payments made in respect of the Pledged Securities to the extent such are permitted pursuant to the terms of the Credit Agreement. 

(g) Any sums paid upon or in respect of the Pledged Securities upon the liquidation or dissolution of any Issuer, unless otherwise subject to
a perfected security interest in favor of the Agent, shall be paid over to the Agent to be held by it hereunder as additional collateral security for the U.S. Guarantor Obligations or the Foreign Obligations, as applicable, and in case any
distribution of capital shall be made on or in respect of the Pledged Securities or any property shall be distributed upon or with respect to the Pledged Securities pursuant to the recapitalization or reclassification of the capital of any Issuer or
pursuant to the reorganization thereof, the property so 

  
 14 

 
distributed shall, unless otherwise subject to a perfected security interest in favor of the Agent, be delivered to the Agent to be held by it hereunder as additional collateral security for the
U.S. Guarantor Obligations or the Foreign Obligations, as applicable. If any sums of money or property so paid or distributed in respect of the Pledged Securities shall be received by such Grantor, such Grantor shall (unless otherwise subject to a
perfected security interest in favor of the Agent) until such money or property is paid or delivered to the Agent, hold such money or property in trust for the Secured Creditors, segregated from other funds of such Grantor, as additional collateral
security for the U.S. Guarantor Obligations or the Foreign Obligations, as applicable. 
 (h) Upon the occurrence and during the
continuance of any Event of Default, all rights of such Grantor to exercise or refrain from exercising the voting and other consensual rights that it would otherwise be entitled to exercise pursuant to Section 6.08(f)(i) hereof and to
receive the payments pursuant to Section 6.08(f)(ii) hereof shall automatically cease, and thereupon the Agent shall be entitled to exercise all voting power with respect to the Pledged Securities and to receive and retain, as additional
collateral hereunder, any and all such payments any time declared or paid upon any of the Pledged Securities during such an Event of Default and otherwise to act with respect to the Pledged Securities as outright owner thereof. 

(i) At any time and from time to time with respect to Pledged Securities other than Pledged Stock of any Borrower or a Subsidiary of any
Borrower and at any time and from time to time during the continuance of an Event of Default with respect to Pledged Stock of a Subsidiary of any Borrower, subject to Applicable Law, the Agent may cause all or any of the Pledged Securities to be
transferred to or registered in its name or the name of its nominee or nominees. 
 (j) Without the prior written consent of the Agent,
such Grantor will not (i) sell, assign, transfer, exchange, or otherwise dispose of, or grant any option with respect to, any of the Investment Property or Proceeds thereof or any interest therein (except pursuant to a transaction permitted by
the Credit Agreement); (ii) create, incur or permit to exist any Lien or option in favor of, or any claim of any Person with respect to, any of the Investment Property or Proceeds thereof, or any interest therein, except for the Security
Interests created by this Agreement and except for nonconsensual Liens permitted by the Credit Agreement (and other, Liens permitted by Sections 7.2(k) and 7.2(m) of the Credit Agreement); or (iii) enter into any agreement or undertaking
expressly restricting the foreclosure of the Agent’s Security Interest in any of the Investment Property or Proceeds thereof or any interest therein (except as expressly permitted by the Credit Agreement). 

(k) In the case of each Grantor which is an Issuer, such Issuer agrees that (i) it will be bound by the applicable terms of this
Agreement relating to the Pledged Securities issued by it and will comply with such terms insofar as such terms are applicable to it, (ii) it will notify the Agent promptly in writing of the occurrence of any of the events described in
Section 6.08(e) or Section 6.08(g) with respect to the Pledged Securities issued by it, and (iii) the terms of Section 6.18 shall apply to it, mutatis 

  
 15 

 
mutandis, with respect to all actions that may be required of it with respect to the Pledged Securities issued by it. Each Grantor which is an Issuer consents to the grant of a Security
Interest in capital stock or other equity interests of such Issuer to the extent provided herein and the exercise of rights by the Agent in respect of such capital stock or other equity interests, including (to the extent permitted hereunder and
under applicable law) the foreclosure thereon, and the Agent, its nominee or transferee becoming a partner or member of any such Issuer that is a partnership or limited liability company. 

(l) If the organizational documents of any Issuer of Pledged Securities restrict the transfer of such Pledged Securities, each such Issuer
shall deliver to the Agent all consents required to authorize the transfer of such Pledged Securities to the Agent or its nominee, or to a third-party transferee upon the exercise by the Agent of it rights and remedies hereunder after the occurrence
and during the continuance of an Event of Default. 
 6.09. Reserved. 

6.10. Electronic Chattel Paper and Transferable Records. If such Grantor shall at any time hold or acquire interests in any electronic
chattel paper or any “transferable record,” as that term is defined in Section 201 of the federal Electronic Signatures in Global and National Commerce Act or in Section 16 of the Uniform Electronic Transactions Act as in effect
in any relevant jurisdiction, such Grantor shall promptly notify the Agent thereof and shall take such action to vest in the Agent control, under Section 9-105 of the UCC, of such electronic chattel paper or control under Section 201 of
the federal Electronic Signatures in Global and National Commerce Act or, as the case may be, Section 16 of the Uniform Electronic Transactions Act, as so in effect in such jurisdiction, of such transferable record. The Agent agrees with such
Grantor that the Agent shall arrange, pursuant to procedures reasonably satisfactory to the Agent and so long as such procedures will not result in the Agent’s loss of control, for such Grantor to make alterations to the electronic chattel
paper or transferable record permitted under Section 9-105 of the UCC or, as the case may be, Section 201 of the federal Electronic Signatures in Global and National Commerce Act or Section 16 of the Uniform Electronic Transactions
Act, unless an Event of Default has occurred and is continuing or would occur after taking into account any action by such Grantor with respect to such electronic chattel paper or transferable record. 

6.11. Letter-of-Credit Rights. If such Grantor shall at any time be beneficiaries under one or more letters of credit, with an
aggregate face value in excess of $250,000 such Grantor shall promptly, but in any case, within five (5) days, notify the Agent thereof and, at the option of the Agent, such Grantor shall either (a) arrange, for the issuer and any
nominated person with respect to such letter of credit to consent, pursuant to an agreement or other authenticated record with and in such form and in substance satisfactory to the Agent, to an assignment to the Agent of the proceeds of any drawing
under the letter of credit or (b) arrange for the Agent to become the transferee beneficiary of the letter of credit. 

  
 16 

 6.12. Commercial Tort Claims. If such Grantor shall at any time hold or acquire one or
more Commercial Tort Claim that it has asserted in an aggregate amount in excess of $500,000 against any other Person or Persons, such Grantor shall immediately, but in any case, within five (5) days, notify the Agent in a writing signed by
such Grantor of the brief details thereof and grant to the Agent for the benefit of the Secured Creditors in such writing a security interest therein and in the proceeds thereof, all upon the terms of this Agreement, with such writing to be in form
and substance reasonably satisfactory to the Agent. 
 6.13. Intellectual Property. Such Grantor agrees to execute one or more
applicable Intellectual Property Security Agreements with respect to its Intellectual Property in order to record the Security Interest granted herein to the Agent for the ratable benefit of the Secured Creditors with the PTO, the Copyright Office,
and, at the Collateral Agent’s request, any other applicable Governmental Authority in the United Kingdom, France, Germany, Spain and Italy within the time period set forth in Section 6.7 of the Credit Agreement. 

6.14. Maintenance of Collateral; Compliance with Laws. Such Grantor shall keep the Collateral provided by it in good order and repair
and shall not use the same in violation in any material respect of any law, subject to Section 6.3 of the Credit Agreement. 
 6.15.
Dispositions of Collateral. Such Grantor shall not sell or otherwise dispose of the Collateral provided by it or any interest therein except for dispositions expressly permitted by the Credit Agreement. 

6.16. Maintenance of Insurance. Such Grantor, at its sole cost and expense, shall maintain or cause to be maintained insurance covering
physical loss or damage to the Collateral provided by it in accordance with the Credit Agreement. 
 6.17. Periodic Certification.
Concurrently with the delivery of each Compliance Certificate, such Grantor shall deliver to the Agent a supplemental perfection certificate (each, a “Perfection Supplement”) executed by such Grantor setting forth a supplement
to the Perfection Certificate with respect to the following items (to the same extent required in the Perfection Certificate delivered on the Closing Date) (i) Name and Related Information, (ii) Intellectual Property, (iii) Current
Locations, (iv) Real Property Owned and Leased, and (v) Deposit Accounts. 
 6.18. Other Actions as to any and all
Collateral. Such Grantor further agrees to take any other action requested by the Agent to insure the attachment, perfection and first priority (subject to Permitted Liens) of, and the ability of the Agent to enforce, the Security Interest in
any and all of the Collateral provided by such Grantor including, without limitation, (a) executing, delivering and, where appropriate, filing financing statements and amendments relating thereto under the UCC, to the extent, if any, that such
Grantor’s signature thereon is required therefor; (b) causing the Agent’s name to be noted as secured party on any certificate of title for a titled good if such 

  
 17 

 
notation is a condition to attachment, perfection or priority of, or ability of the Agent to enforce, the Security Interest in such Collateral; (c) complying with any provision of any
statute, regulation or treaty of the United States of America as to any Collateral if compliance with such provision is a condition to the attachment, perfection or priority of, or the ability of the Agent to enforce, the Security Interest in such
Collateral; (d) obtaining governmental and other third-party consents and approvals, including without limitation any consent of any licensor, lessor or other person obligated on such Collateral; (e) obtaining waivers from mortgagees,
bailees, landlords and any other person who has possession of or any interest in any Collateral or any real property on which any such Collateral may be located, in form and substance satisfactory to the Agent, but only to the extent required by
Section 6.7 of the Credit Agreement; (f) to the extent required in the Credit Agreement, providing to the Agent “control” over such Collateral, to the extent that perfection can only be achieved under the UCC by control or
where obtaining perfection by control provides more protection to the Secured Creditors that perfection by filing a financing statement; and (g) taking all actions required by the UCC or by other law, as applicable in any relevant UCC
jurisdiction, or by other law as applicable in any foreign jurisdiction; provided, that (i) no actions in respect of Intellectual Property shall be required to be taken outside the United States, Germany, France, Italy, Spain or the
United Kingdom, and (ii) no further actions, undertakings or representations with respect to Intellectual Property shall be required other than those set forth in the Forms of Intellectual Property Security Agreements attached to this Security
Agreement. 
 Section 7. RESERVED. 

Section 8. COLLATERAL PROTECTION EXPENSES; PRESERVATION OF
COLLATERAL. 
 8.01. Expenses Incurred by the Agent. Upon the occurrence and during the continuation of any Default or
Event of Default, the Agent may, if the relevant Grantor fails to do so, discharge taxes and other encumbrances at any time levied or placed on any portion of the Collateral, make repairs thereto and pay any necessary filing fees or insurance
premiums. Subject to Section 18.12, each Grantor agrees to reimburse the Agent on demand for any and all expenditures so made, and all sums disbursed by the Agent in connection with this Section 8.01, including reasonable
attorneys’ fees, court costs, expenses and other charges relating thereto, shall be payable, upon demand, by such Grantor to the Agent shall bear interest at the per annum rate specified in Section 16 and shall constitute additional
U.S. Guarantor Obligations or Foreign Obligations, as applicable. The Agent shall have no obligation to any Grantor to make any such expenditures, nor shall the making thereof relieve any Grantor of any default. 

8.02. Agent’s Obligations and Duties. 

(a) Neither the Agent nor any other Secured Creditor shall have any obligation or liability under any contract or agreement constituting
Collateral by reason 

  
 18 

 
of or arising out of this Agreement or the receipt by the Agent or any other Secured Creditor of any payment relating to any of the Collateral, nor shall the Agent or any other Secured Creditor
be obligated in any manner to perform any of the obligations of any Grantor under or pursuant to any such contract or agreement, to make inquiry as to the nature or sufficiency of any payment received by the Agent or any other Secured Creditor in
respect of the Collateral or as to the sufficiency of any performance by any party under any such contract or agreement, to present or file any claim, to take any action to enforce any performance or to collect the payment of any amounts which may
have been assigned to the Agent or any other Secured Creditor or to which the Agent or any other Secured Creditor may be entitled at any time or times. 

(b) The Agent’s sole duty with respect to the custody, safekeeping and physical preservation of the Collateral in its possession, under
Section 9-207 of the NYUCC or otherwise, shall be to deal with such Collateral in the same manner as the Agent deals with similar property for its own account. 

(c) Neither the Agent, nor any other Secured Creditor nor any of their respective officers, directors, partners, employees, agents, attorneys
and other advisors, attorneys-in-fact or affiliates shall be liable for failure to demand, collect or realize upon any of the Collateral or for any delay in doing so or shall be under any obligation to sell or otherwise dispose of any Collateral
upon the request of any Grantor or any other Person or to take any other action whatsoever with regard to the Collateral or any part thereof. The powers conferred on the Secured Creditors hereunder are solely to protect the Secured Creditors’
interests in the Collateral and shall not impose any duty upon any Secured Creditor to exercise any such powers. The Secured Creditors shall be accountable only for amounts that they actually receive as a result of the exercise of such powers, and
neither they nor any of their officers, directors, partners, employees, agents, attorneys and other advisors, attorneys-in-fact or affiliates shall be responsible to any Grantor for any act or failure to act hereunder, except to the extent that any
such act or failure to act is found by a final and non-appealable decision of a court of competent jurisdiction to have resulted from their respective gross negligence or willful misconduct. 

(d) Each Grantor acknowledges that the rights and responsibilities of the Agent under this Agreement with respect to any action taken by the
Agent or the exercise or non-exercise by the Agent of any option, voting right, request, judgment or other right or remedy provided for herein or resulting or arising out of this Agreement shall, as between the Agent and the other Secured Creditors,
be governed by the Credit Agreement and by such other agreements with respect thereto as may exist from time to time among them, but, as between the Agent and the Grantors, the Agent shall be conclusively presumed to be acting as agent for the
Secured Creditors with full and valid authority so to act or refrain from acting, and no Grantor shall be under any obligation, or entitlement, to make any inquiry respecting such authority. 

  
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 8.03. Duties as to Pledged Securities. 

(a) With respect to any calls, conversions, exchanges, redemptions, offers, tenders or similar matters relating to any such Pledged
Securities (herein called “Events”), any duty in connection therewith imposed on the Agent by Applicable Law shall be fully satisfied if: 

(i) the Agent exercises reasonable care to ascertain the occurrence and to give reasonable notice to the applicable Grantor of any Events
applicable to any Pledged Securities that are registered and held in the name of Agent or its nominee; 
 (ii) the Agent gives the
applicable Grantor reasonable notice of the occurrence of any Events of which the Agent has received actual knowledge, which Events are applicable to any securities that are in bearer form or are not registered and held in the name of the Agent or
its nominee (each Grantor agreeing to give the Agent reasonable notice of the occurrence of any Events of which such Grantor has knowledge, which Events are applicable to any securities in the possession of the Agent); and 

(iii) the Agent endeavors to take such action with respect to any of the Events as the applicable Grantor may reasonably and specifically
request in writing in sufficient time for such action to be evaluated and taken or, if the Agent believes that the action requested would adversely affect the value of the Pledged Securities as collateral or the collection of the U.S. Guarantor
Obligations or the Foreign Obligations, as applicable, or would otherwise prejudice the interests of any Secured Creditor, the Agent gives notice to such Grantor that any such requested action will not be taken and, if the Agent makes such
determination or if such Grantor fails to make such timely request, the Agent takes such other action as it deems advisable in the circumstances. 

(b) Except as hereinabove specifically set forth, neither the Agent nor any other Secured Creditor shall have any further obligation to
ascertain the occurrence of, or to notify any Grantor with respect to, any Events and shall not be deemed to assume any such further obligation as a result of the establishment by the Agent or any other Secured Creditor of any internal procedures
with respect to any securities in its possession, nor shall the Agent or any other Secured Creditor be deemed to assume any other responsibility for, or obligation or duty with respect to, any Pledged Securities or its use of any nature or kind, or
any matter or proceedings arising out of or relating thereto, including, without limitation, any obligation or duty to take any action to collect, preserve or protect its or any Grantor’s rights in the Pledged Securities or against any prior
parties thereto, but the same shall be at such Grantor’s sole risk and responsibility at all times. 
 (c) Nothing contained in this
Section 8.03 shall be deemed to create any obligation in respect of Events on the Agent, the purpose of this Section 8.03 being solely to provide standards, in the event that Applicable Law imposes any obligations on the
Agent as to Events. 

  
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 Section 9. SECURITIES AND DEPOSITS. Without
limitation of Section 6.08, but subject to Section 6.08(f)(i), after the occurrence and during the continuation of an Event of Default, the Agent may at any time at its option, transfer to itself or any nominee any securities
constituting Collateral, and, subject to Section 6.08(f)(ii), receive any income thereon and hold such income as additional Collateral or apply it to the U.S. Guarantor Obligations or the Foreign Obligations, as applicable. The Agent may
after the occurrence and during the continuance of an Event of Default demand, sue for, collect, or make any settlement or compromise which it deems desirable with respect to the Collateral. 

Section 10. NOTIFICATION TO ACCOUNT DEBTORS AND
OTHER PERSONS OBLIGATED ON COLLATERAL. If an Event of Default shall have occurred and be continuing, each Grantor shall, at the request of Agent, notify account debtors and
other persons obligated on any of the Collateral of such Grantor of the Security Interest in any account, chattel paper, General Intangible, instrument or other claims constituting Collateral that payment thereof is to be made directly to the Agent
or to any financial institution designated by the Agent as the Agent’s agent therefor, and the Agent may itself, if an Event of Default shall have occurred and be continuing, without notice to or demand upon any Grantor, so notify account
debtors and other persons obligated on Collateral. After the making of such a request or the giving of any such notification, each Grantor shall hold any proceeds of collection of accounts, chattel paper, General Intangibles, instruments and other
claims constituting Collateral received by the Grantor as trustee for the Secured Creditors without commingling the same with other funds of the Grantor and shall turn the same over to the Agent in the identical form received, together with any
necessary endorsements or assignments. The Agent shall have no liability or responsibility to any Grantor for acceptance of a check, draft or other order for payment of money bearing the legend “payment in full” or words of similar import
or any other restrictive legend or endorsement or be responsible for determining the correctness of any remittance. Without limitation of the foregoing, during the continuation of an Event of Default (1) the Agent shall have the right, but not
the obligation, to make test verifications of the accounts in any manner and through any medium that it reasonably considers advisable, and the Grantors shall furnish all such assistance and information as the Agent may require in connection with
such test verifications, and (2) the Agent in its own name or in the name of others may communicate with account debtors on the accounts to verify with them to the Agent’s satisfaction the existence, amount and terms of any accounts.
Subject to Section 18.12, during the continuation of an Event of Default, the Agent may apply the proceeds of collection of accounts, chattel paper, general intangibles, instruments and other claims constituting Collateral received by
the Agent or any other Secured Creditor to the Foreign Obligations or the U.S. Guarantor Obligations, as applicable, and unless otherwise subject to a perfected security interest in favor of the Agent, hold such proceeds as additional Collateral, at
the option of the Agent. The provisions of Section 9-209 of the NYUCC shall not apply to any account, chattel paper or payment intangible as to which notification of assignment has been sent to the account debtor or other person obligation on
the Collateral, whether under this Section 9, Section 11 or Section 12. 

  
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 Section 11. POWER OF ATTORNEY. 

11.01. Appointment and Powers of Agent. Upon the occurrence and during the continuation of an Event of Default, each Grantor hereby
irrevocably constitutes and appoints the Agent and any officer or agent thereof, with full power of substitution, as its true and lawful attorney-in-fact with full irrevocable power and authority in the place and stead of such Grantor and in the
name of such Grantor or in its own name, for the purpose of carrying out the terms of this Agreement, to take any and all appropriate action and to execute any and all documents and instruments which may be necessary or desirable to accomplish the
purposes of this Agreement, and, without limiting the generality of the foregoing, each Grantor hereby gives the Agent the power and right, on behalf of such Grantor, without notice to or assent by such Grantor, to do any or all of the following:

 (a) in the name of such Grantor or its own name, or otherwise, take possession of and endorse and collect any checks, drafts, notes,
acceptances or other instruments for the payment of moneys due under any Receivable or with respect to any other Collateral and file any claim or take any other action or proceeding in any court of law or equity or otherwise deemed appropriate by
the Agent for the purpose of collecting any and all such moneys due under any Receivable or with respect to any other Collateral whenever payable; 

(b) in the case of any Intellectual Property, execute and deliver, and record or have recorded, any and all agreements, instruments,
documents and papers as the Agent may request to evidence the Security Interest in such Intellectual Property, and the goodwill and General Intangibles of such Grantor relating thereto or represented thereby; 

(c) pay or discharge taxes and Liens levied or placed on or threatened against the Collateral, effect any repairs or provide any insurance
and pay all or any part of the premiums therefor and the costs thereof; 
 (d) execute, in connection with any sale provided for in
Section 12, any endorsements, assignments or other instruments of conveyance or transfer with respect to the Collateral; 
 (e)
exercise all rights of such Grantor as owner of the Pledged Securities or as party to any partnership, limited liability company or similar agreement, including, without limitation, the right to sign any and all amendments, instruments,
certificates, proxies, and other writings and exercise all voting and consent rights with respect to the Pledged Securities; 
 (f) (1)
direct any party liable for any payment under any of the Collateral to make payment of any and all moneys due or to become due thereunder directly to the Agent or as the Agent shall direct; (2) ask or demand for, collect, and receive payment of
and receipt for, any and all moneys, claims and other amounts due or 

  
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to become due at any time in respect of or arising out of any Collateral; (3) sign and endorse any invoices, freight or express bills, bills of lading, storage or warehouse receipts, drafts
against debtors, assignments, verifications, notices and other documents in connection with any of the Collateral; (4) commence and prosecute any suits, actions or proceedings at law or in equity in any court of competent jurisdiction to
collect the Collateral or any portion thereof and to enforce any other right in respect of any Collateral; (5) defend any suit, action or proceeding brought against such Grantor with respect to any Collateral; (6) settle, compromise or
adjust any such suit, action or proceeding and, in connection therewith, give such discharges or releases as the Agent may deem appropriate; (7) assign any Copyright, Patent or Trademark (along with the goodwill of the business to which any
such Copyright, Patent or Trademark pertains) throughout the world for such term or terms, on such conditions, and in such manner, as the Agent shall in its sole discretion determine; and (8) generally, sell, transfer, pledge and make any
agreement with respect to or otherwise deal with any of the Collateral as fully and completely as though the Agent were the absolute owner thereof for all purposes, and do, at the Agent’s option and such Grantor’s expense, at any time, or
from time to time, all acts and things which the Agent deems necessary to protect, preserve or realize upon the Collateral and the Security Interest therein and to effect the intent of this Agreement, all as fully and effectively as such Grantor
might do; and 
 (g) to the extent that such Grantor’s authorization given in Section 3 is not sufficient, to file such
financing statements or similar documents under the laws of any jurisdiction with respect hereto, with or without such Grantor’s signature, or a photocopy of this Agreement in substitution for a financing statement or such other document, as
the Agent may deem appropriate and to execute in such Grantor’s name such financing statements, other such documents and amendments thereto and continuation statements which may require such Grantor’s signature. 

11.02. Failure of Grantor to Perform. If any Grantor fails to perform or comply with any of its agreements contained herein, the Agent,
at its option, but without any obligation so to do, may perform or comply, or otherwise cause performance or compliance, with such agreement. 

11.03. Expenses of Attorney-in-Fact. The expenses of the Agent incurred in connection with actions undertaken as provided in this
Section 11, together with interest thereon at a rate per annum equal to the Default Rate, from the date of payment by the Agent to the date reimbursed by the relevant Grantor, shall be payable by such Grantor to the Agent on demand. 

11.04. Ratification by Grantor. To the extent permitted by law, each Grantor hereby ratifies all that said attorneys shall lawfully do
or cause to be done by virtue of this Section 11. This power of attorney is a power coupled with an interest and is irrevocable. 

11.05. No Duty on Agent. The powers conferred on the Agent, its directors, officers and agents pursuant to this Section 11
are solely to protect the Secured 

  
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Creditors’ interests in the Collateral and shall not impose any duty upon any of them to exercise any such powers. Each Secured Creditor shall be accountable only for the amounts that it
actually receives as a result of the exercise of such powers, and neither it nor any of its officers, directors, employees or agents shall be responsible to any Grantor for any act or failure to act, except for such Secured Creditor’s own gross
negligence or willful misconduct as determined in a final and non-appealable judgment by a court of competent jurisdiction. 

Section 12. REMEDIES. 

12.01. Default. Grantors shall be in default under this Agreement (a) whenever any Event of Default has occurred and is continuing
(and each of the Grantors shall thereupon be in default hereunder without regard to whether or to what degree any Grantor individually may have caused, participated in, or had any knowledge of the occurrence of such Event of Default) and (b) at
all times after any Loan has become due and payable and remains unpaid beyond any applicable grace period, whether at maturity, upon acceleration pursuant to the Credit Agreement or otherwise. 

12.02. Remedies Upon Default. At any time when any Grantor is in default under this Agreement as set forth in
Section 12.01, the Agent may exercise and enforce, in any order, (i) each and all of the rights and remedies available to a secured party upon default under the NYUCC or any other applicable UCC or other Applicable Law,
(ii) each and all of the rights and remedies available to it under the Credit Agreement or any other Loan Document, and (iii) each and all of the following rights and remedies: 

(a) Collection Rights. Without notice to any Grantor or any other Loan Party, the Agent may notify any or all account debtors and
obligors on any accounts, instruments, general intangibles or other claims constituting Collateral of the Secured Creditors’ Security Interests therein and may direct, demand and enforce payment thereof directly to the Agent. The provisions of
Section 9-209 of the NYUCC shall not apply to any account, chattel paper or payment intangible as to which notification of assignment has been sent to the account debtor. 

(b) Taking Possession. The Agent may (i) enter upon any and all premises owned or leased by any Grantor where Collateral is
located (or believed by the Agent to be located), with or (to the fullest extent permitted by law) without judicial process and without any obligation to pay rent; (ii) prior to the disposition of the Collateral, store, process, repair or
recondition the Collateral or otherwise prepare the Collateral for disposition in any manner to the extent the Agent deems appropriate; (iii) take possession of any Grantor’s premises or place custodians in exclusive control thereof,
remain on such premises and use the same and any Grantor’s equipment for the purpose of completing any work in process or otherwise preparing the Collateral for sale or selling or otherwise transferring the Collateral; (iv) take possession
of all items of Collateral that are not then in its possession, either upon such premises or by removal from such premises; and (v) require any Grantor or the Person in possession thereof to deliver such Collateral to the Agent at one or more
locations designated by the Agent and reasonably convenient to it and each Grantor owning an interest therein. 

  
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 (c) Foreclosure. The Agent may sell, lease, license or otherwise dispose of or transfer
any or all of the Collateral or any part thereof in one or more parcels at public sale or in private sale or transaction, on any exchange or market or at the Agent’s offices or on any Grantor’s premises or at any other location, for cash,
on credit or for future delivery, and may enter into all contracts necessary or appropriate in connection therewith, without any notice whatsoever unless required by law. Where permitted by law, one or more of the Secured Creditors may be the
purchasers at any such sale and in such event, the Secured Creditors bidding at such sale may bid part or all of the U.S. Guarantor Obligations or the Foreign Obligations, as applicable, owing to them without necessity of any cash payment on account
of the purchase price, even though any other purchaser at such sale is required to bid a purchase price payable in cash. Each Grantor agrees that at least ten (10) business days’ written notice to such Grantor of the time and place of any
public sale of Collateral owned by it (or, to the extent such Grantor is entitled by law to notice thereof, the public sale of any other Collateral), or the time after which any private sale of Collateral owned by it (or, to the extent such Grantor
is entitled by law to notice thereof, the private sale of any other Collateral) is to be made, shall be commercially reasonable. For purposes of such notice, to the fullest extent permitted by law (i) each Grantor waives notice of any sale of
Collateral owned by any other Grantor and (ii) each Grantor agrees that notice given to any Borrower shall constitute notice given to such Grantor. The giving of notice of any such sale or other disposition shall not obligate the Agent to
proceed with the sale or disposition, and any such sale or disposition may be postponed or adjourned from time to time, without further notice. 

(d) Voting Rights. The Agent may exercise any and all rights of any Grantor as the owner of any Pledged Securities, including, without
limitation, voting rights, rights to give or withhold consent under any agreement under which any Pledged Security is issued and all other rights referred to in Section 11.01(e). 

(e) Use of Intellectual Property. The Agent may, on a royalty-free basis, use and license use of any Trademark, Trade Secret, trade
name, trade style, Copyright, Patent, technical knowledge or process or other Intellectual Property owned, held or used by any Grantor in respect of any Collateral as to which any right or remedy of the Agent is exercised or enforced. In addition,
the Agent may exercise and enforce such rights and remedies for collection as may be available to it by law or agreement. Each Grantor grants a license pursuant to Section 12.03 in connection therewith. 

(f) Use of Collateral. With respect to any Collateral in the possession of the Agent or any other Secured Creditor, or a bailee or
other third party holding on its behalf, the Agent or such other Secured Creditor may use or operate such Collateral in any manner and to the extent determined by the Agent or such Secured Creditor. 

  
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 (g) Appointment of Receiver. Without limiting any other right or remedy of the Agent in
this Agreement, upon the occurrence and during the continuance of any Event of Default, the Agent may by instrument in writing appoint any person as a receiver of all or any part of the Collateral of each applicable Grantor. The Agent may from time
to time remove or replace a receiver, or make application to any court of competent jurisdiction for the appointment of a receiver. Any receiver appointed by the Agent shall (for purposes relating to responsibility for the receiver’s acts or
omissions) be considered to be the agent of each applicable Grantor. The Agent may from time to time fix the receiver’s remuneration and the Grantors shall pay the amount of such remuneration to the Agent. The Agent shall not be liable to any
Grantor or any other person in connection with appointing or not appointing a receiver or in connection with the receiver’s actions or omissions. 

12.03. Grant of License to Use Intellectual Property. For the purpose of enabling the Agent to exercise rights and remedies
under this Section 12 at such time as the Agent shall be lawfully and otherwise entitled to exercise such rights and remedies, each Grantor hereby grants to the Agent an irrevocable, nonexclusive license (exercisable without payment of
royalty or other compensation to such Grantor) to use, license or sub-license any of the Collateral consisting of Intellectual Property now owned or hereafter acquired by the Grantor to the extent that such Grantor is not legally or contractually
prohibited from doing so (Grantor agreeing to use commercially reasonable efforts not to enter into, after the Closing Date, any such contractual prohibition), and wherever the same may be located, and including in such license reasonable access to
all media in which any of the licensed items may be recorded or stored and to all computer software and programs used for the compilation or printout thereof. The use of such license by the Agent shall be exercised, at the Agent’s option, only
upon the occurrence and during the continuation of an Event of Default; provided that any license, sub-license or other transaction entered into by the Agent in accordance herewith shall be binding upon each Grantor notwithstanding any
subsequent cure, waiver or other termination of an Event of Default. 
 12.04. Waivers by Grantors. Each Grantor hereby irrevocably
waives (a) all rights of redemption from any foreclosure sale; (b) the benefit of all valuation, appraisal, exemption and moratorium laws; (c) to the fullest extent permitted by law, all rights to notice or a hearing prior to the
exercise by the Agent of its right to take possession of any Collateral, whether by self-help or by legal process and any right to object to the Agent taking possession of any Collateral by self-help; and (d) if the Agent seeks to obtain
possession of any Collateral by replevin, claim and delivery, attachment, levy or other legal process, (i) any notice or demand for possession prior to the commencement of legal proceedings, (ii) the posting of any bond or security in any
such proceedings, and (iii) any requirement that the Agent retain possession and not dispose of any Collateral until after a trial or final judgment in such proceedings. 

12.05. Application of Proceeds. Subject to Section 18.12, and except as expressly provided elsewhere in this Agreement, all
proceeds received by the Agent in respect of any sale of, collection from, or other realization upon all or any part of the 

  
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Collateral may, in the discretion of the Agent, be held by the Agent as Collateral for, or then, or at any other time thereafter, applied in full or in part by the Agent against, the U.S.
Guarantor Obligations and the Foreign Obligations, as applicable, in the following order of priority: 
 FIRST: to the
payment of all reasonable costs and expenses of such sale, collection or other realization, including reasonable compensation to the Agent and its agents and counsel, and all other reasonable expenses, liabilities and advances made or incurred by
the Agent in connection therewith, and all amounts for which the Agent is entitled to indemnification hereunder and all reasonable advances made by the Agent hereunder for the account of any Grantor, and to the payment of all reasonable costs and
expenses paid or incurred by the Agent in connection with the exercise of any right or remedy hereunder, all in accordance with Section 18.09; 

SECOND: to the payment of all other U.S. Guarantor Obligations and Foreign Obligations (for the ratable benefit of the holders
thereof) then due and payable in the manner and order provided in the Credit Agreement; 
 THIRD: to any payments required
by Section 9-608(a)(1)(C) or 9-615(a)(3) of the NYUCC or in accordance with other Applicable Law; and 
 FOURTH, to the
payment to or upon the order of the Grantor entitled thereto, or to whomsoever may be lawfully entitled to receive the same or as a court of competent jurisdiction may direct, of any surplus then remaining from such proceeds. 

12.06. Surplus; Deficiency. Any surplus proceeds of any sale or other disposition by the Agent of any Collateral remaining after
discharge of the Credit Agreement and after all U.S. Guarantor Obligations or the Foreign Obligations, as applicable are Paid in Full and in cash and any payments required by Section 9-608(a)(1)(C) or 9-615(a)(3) of the NYUCC are Paid in Full
shall be paid over to the Grantor entitled thereto, or to whomever may be lawfully entitled to receive such surplus or as a court of competent jurisdiction may direct, but prior to termination and discharge of the Credit Agreement, such surplus
proceeds may be retained by the Agent and held as Collateral until termination and discharge of the Credit Agreement. The Borrowers and each other Grantor shall be and remain liable for any deficiency. 

12.07. Information Related to the Collateral. If, during the continuance of an Event of Default, the Agent determines to sell or
otherwise transfer any Collateral, each Grantor shall, and shall cause any Person controlled by it to, furnish to the Agent all information the Agent may request that pertains or could pertain to the value or condition of the Collateral or that
would or might facilitate such sale or transfer. The Agent shall have the right, notwithstanding any confidentiality obligation or agreement otherwise binding upon it, freely (but not in violation of any law, including federal securities laws) to
disclose such information, and any and all other information 

  
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(including confidential information) pertaining in any manner to the Collateral or the assets, liabilities, results of operations, business or prospects of any Secured Creditors, freely to any
Person that the Agent in good faith believes to be a potential or prospective purchaser in such sale or transfer, without liability for any disclosure, dissemination or use that may be made as to such information by any such Person. 

12.08. Sale Exempt from Registration. The Agent shall be entitled at any such sale or other transfer, if it deems it advisable to do
so, to restrict the prospective bidders or purchasers to Persons who will provide assurances satisfactory to the Agent that the Collateral may be offered and sold to them without registration under the Securities Act, and without registration or
qualification under any other applicable state or federal law. Upon the consummation of any such sale, the Agent shall have the right to assign, transfer and deliver to the purchaser or purchasers thereof the Collateral so sold. The Agent may
solicit offers to buy the Collateral, or any part of it, from a limited number of investors deemed by the Agent, in its good faith judgment or in good faith reliance upon advice of its counsel, to meet the requirements to purchase securities under
Regulation D promulgated under the Securities Act (or any other regulation of similar import). If the Agent solicits such offers from such investors, then the acceptance by the Agent of the highest offer obtained from any of them shall be deemed to
be a commercially reasonable method of disposition of the Collateral. Each Grantor recognizes that, by reason of certain prohibitions contained in the Securities Act and applicable state securities laws, Agent may be compelled, with respect to any
sale of all or any part of the Pledged Securities conducted without prior registration or qualification of such Pledged Securities under the Securities Act and/or such state securities laws, to limit purchasers to those who will agree, among other
things, to acquire the Pledged Securities for their own account, for investment and not with a view to the distribution or resale thereof. Each Grantor acknowledges that any such private placement may be at prices and on terms less favorable than
those obtainable through a sale without such restrictions (including an offering made pursuant to a registration statement under the Securities Act) and, notwithstanding such circumstances and the registration rights granted to Agent by such Grantor
pursuant hereto, each Grantor agrees that any such private placement shall not be deemed, in and of itself, to be commercially unreasonable solely because it is a private placement and that Agent shall have no obligation to delay the sale of any
Pledged Securities for the period of time necessary to permit the issuer thereof to register it for a form of sale requiring registration under the Securities Act or under applicable state securities laws, even if such issuer would, or should, agree
to so register it. If Agent determines to exercise its right to sell any or all of the Pledged Securities, upon written request, each Grantor shall and shall cause each issuer of any Pledged Securities to be sold hereunder from time to time to
furnish to Agent all such information as Agent may request in order to determine the amount of Pledged Securities which may be sold by Agent in exempt transactions under the Securities Act and the rules and regulations of the Securities and Exchange
Commission thereunder, as the same are from time to time in effect. 
 12.09. Rights and Remedies Cumulative. The rights provided for
in this Agreement and the other Loan Documents are cumulative and are not exclusive of any 

  
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other rights, powers or privileges or remedies provided by law or in equity, or under any other instrument, document or agreement. The Agent may exercise and enforce each right and remedy
available to it either before or concurrently with or after, and independently of, any exercise or enforcement of any other right or remedy of the Agent or any other Secured Creditor against any Person or property. All such rights and remedies shall
be cumulative, and no one of them shall exclude or preclude any other. 
 12.10. No Direct Enforcement by Secured Creditors. The
Agent may freely exercise and enforce any and all of its rights and remedies hereunder, for the benefit of the Secured Creditors. Except to the extent the Agent may consent in writing, no Secured Creditor, other than the Agent, shall have any
independent right to collect, take possession of, foreclose against or otherwise enforce the Security Interests granted hereby. 

Section 13. STANDARDS FOR EXERCISING REMEDIES. 

13.01. Commercially Reasonable Manner. To the extent that Applicable Law imposes duties on the Agent to exercise remedies in a
commercially reasonable manner, each Grantor acknowledges and agrees that it is not commercially unreasonable for the Agent (a) to fail to incur expenses reasonably deemed significant by the Agent to prepare Collateral for disposition or
otherwise to complete raw material or work in process into finished goods or other finished products for disposition or to postpone any such disposition pending any such preparation or processing; (b) to fail to obtain third-party consents for
access to Collateral to be disposed of, or to obtain or, if not required by other law, to fail to obtain governmental or third-party consents for the collection or disposition of Collateral to be collected or disposed of; (c) to fail to
exercise collection remedies against account debtors or other persons obligated on Collateral or to remove any Lien on or any adverse claims against Collateral; (d) to exercise collection remedies against account debtors and other persons
obligated on Collateral directly or through the use of collection agencies and other collection specialists; (e) to advertise dispositions of Collateral through publications or media of general circulation, whether or not the Collateral is of a
specialized nature; (f) to contact other persons, whether or not in the same business as such Grantor, for expressions of interest in acquiring all or any portion of the Collateral; (g) to hire one or more professional auctioneers to
assist in the disposition of Collateral, whether or not the collateral is of a specialized nature; (h) to dispose of Collateral by utilizing Internet sites that provide for the auction of assets of the types included in the Collateral or that
have the reasonable capability of doing so, or that match buyers and sellers of assets; (i) to dispose of assets in wholesale rather than retail markets; (j) to disclaim disposition warranties; (k) to purchase insurance or credit
enhancements to insure the Agent against risks of loss, collection or disposition of Collateral or to provide to the Agent a guaranteed return from the collection or disposition of Collateral; or (l) to the extent deemed appropriate by the
Agent, to obtain the services of other brokers, investment bankers, consultants and other professionals to assist the Agent in the collection or disposition of any of the Collateral. Each Grantor acknowledges that the purpose of this
Section 13 is to provide non-exhaustive indications of what actions or omissions by the Agent would not be commercially 

  
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unreasonable in the Agent’s exercise of remedies against the Collateral and that other actions or omissions by the Agent shall not be deemed commercially unreasonable solely on account of
not being indicated in this Section 13. Without limiting the foregoing, nothing contained in this Section 13 shall be construed to grant any rights to any Grantor or to impose any duties on the Agent that would not have been
granted or imposed by this Agreement or by Applicable Law in the absence of this Section 13. 
 13.02. Standard of Care.
The powers conferred on the Agent hereunder are solely to protect its interest in the Collateral and shall not impose any duty upon it to exercise any such powers. Except for the exercise of reasonable care in the custody of any Collateral in its
possession and the accounting for moneys actually received by it hereunder, the Agent shall have no duty as to any Collateral or as to the taking of any necessary steps to preserve rights against prior parties or to protect, preserve, vote or
exercise any rights pertaining to any Collateral. The Agent shall be deemed to have exercised reasonable care in the custody and preservation of Collateral in its possession if such Collateral is accorded treatment substantially equal to that which
the Agent accords its own property or if it selects, with reasonable care, a custodian to hold such Collateral on its behalf. 

Section 14. WAIVERS BY GRANTOR; OBLIGATIONS ABSOLUTE. 

14.01. Specific Waivers. Each Grantor waives demand, notice, protest, notice of acceptance of this Agreement, notice of loans made,
credit extended, Collateral received or delivered or other action taken in reliance hereon and all other demands and notices of any description other than those required pursuant to the Credit Agreement or any other Loan Documents to which such
Grantor is a party. 
 14.02. Obligations Absolute. All rights of the Agent hereunder, the Security Interest and all obligations of
the Grantors hereunder shall be absolute and unconditional irrespective of (a) any lack of validity or enforceability of the Credit Agreement, any other Loan Document, any agreement with respect to any of the U.S. Guarantor Obligations or the
Foreign Obligations, as applicable, or any other agreement or instrument relating to any of the foregoing; (b) any change in the time, manner or place of payment of, or in any other term of, all or any of the U.S. Guarantor Obligations or the
Foreign Obligations, as applicable, or any other amendment or waiver of or any consent to any departure from the Credit Agreement, any other Loan Document, or any other agreement or instrument; (c) any exchange, release or non-perfection of any
Lien on other collateral, or any release or amendment or waiver of or consent under or departure from or any acceptance of partial payment thereon and or settlement, compromise or adjustment of any Secured Obligation or of any guarantee, securing or
guaranteeing all or any of the U.S. Guarantor Obligations or the Foreign Obligations, as applicable; or (d) any other circumstance that might otherwise constitute a defense available to, or a discharge of, any Grantor in respect of the U.S.
Guarantor Obligations or the Foreign Obligations, as applicable, or this Agreement other than the prompt and complete performance and payment in full of the U.S. Guarantor Obligations or the Foreign Obligations, as applicable. 

  
 30 

 Section 15. MARSHALLING. The Agent shall not be required to marshal any
present or future collateral security (including but not limited to this Agreement and the Collateral) for, or other assurances of payment of, the U.S. Guarantor Obligations or the Foreign Obligations, as applicableor any of them or to resort to
such collateral security or other assurances of payment in any particular order, and all of its rights hereunder and in respect of such collateral security and other assurances of payment shall be cumulative and in addition to all other rights,
however existing or arising. To the extent that it lawfully may, each Grantor hereby agrees that it shall not invoke any law relating to the marshalling of collateral which might cause delay in or impede the enforcement of the Agent’s rights
under this Agreement or under any other instrument creating or evidencing any of the U.S. Guarantor Obligations or the Foreign Obligations, as applicable, or under which any of the Obligations is outstanding or by which any of the U.S. Guarantor
Obligations or the Foreign Obligations, as applicable, is secured or payment thereof is otherwise assured, and, to the extent that it lawfully may, each Grantor hereby irrevocably waives the benefits of all such laws. 

Section 16. INTEREST. Until paid, all amounts due and payable by each Grantor hereunder shall be a debt secured by the
Collateral and shall bear, whether before or after judgment, interest at a rate per annum equal to the Default Rate, from the date of payment by the Agent to the date reimbursed by such Grantor, and such interest shall be payable by such Grantor to
the Agent on demand. 
 Section 17. REINSTATEMENT. The obligations of each Grantor pursuant to this Agreement shall
continue to be effective or automatically be reinstated, as the case may be, if at any time payment of any of the U.S. Guarantor Obligations or the Foreign Obligations, as applicable, is rescinded or otherwise must be restored or returned by the
Agent or any other Secured Creditor upon the insolvency, bankruptcy, dissolution, liquidation or reorganization of such Grantor or any other obligor or otherwise, all as though such payment had not been made. 

Section 18. MISCELLANEOUS. 

18.01. Notices. All notices, requests and demands to or upon the Agent or any Grantor hereunder shall be effected in the manner
provided for in Section 10.2 of the Credit Agreement. 
 18.02. GOVERNING LAW; CONSENT TO JURISDICTION; SERVICE OF PROCESS. THIS
AGREEMENT SHALL BE A CONTRACT MADE UNDER AND GOVERNED BY THE INTERNAL LAWS OF THE STATE OF NEW YORK APPLICABLE TO CONTRACTS MADE AND TO BE PERFORMED ENTIRELY WITHIN SUCH STATE, WITHOUT REGARD TO CONFLICT OF LAWS PRINCIPLES (OTHER THAN SECTION
5-1401 OF THE NEW YORK GENERAL OBLIGATIONS LAW). ANY LITIGATION BASED HEREON, OR ARISING OUT OF, UNDER, OR IN CONNECTION WITH THIS AGREEMENT OR ANY OTHER LOAN DOCUMENT, SHALL BE BROUGHT AND MAINTAINED EXCLUSIVELY IN THE COURTS OF THE STATE OF NEW
YORK OR IN THE 

  
 31 

 
UNITED STATES DISTRICT COURT FOR THE SOUTHERN DISTRICT OF NEW YORK; PROVIDED THAT ANY SUIT SEEKING ENFORCEMENT AGAINST ANY COLLATERAL OR OTHER PROPERTY MAY BE BROUGHT, AT AGENT’S
OPTION, IN THE COURTS OF ANY JURISDICTION WHERE SUCH COLLATERAL OR OTHER PROPERTY MAY BE FOUND. EACH PARTY HERETO HEREBY EXPRESSLY AND IRREVOCABLY SUBMITS TO THE JURISDICTION OF THE COURTS OF THE STATE OF NEW YORK AND OF THE UNITED STATES DISTRICT
COURT FOR THE SOUTHERN DISTRICT OF NEW YORK FOR THE PURPOSE OF ANY SUCH LITIGATION AS SET FORTH ABOVE. EACH PARTY HERETO FURTHER IRREVOCABLY CONSENTS TO THE SERVICE OF PROCESS BY REGISTERED MAIL, POSTAGE PREPAID, OR BY PERSONAL SERVICE WITHIN OR
WITHOUT THE STATE OF NEW YORK. EACH PARTY HERETO HEREBY EXPRESSLY AND IRREVOCABLY WAIVES, TO THE FULLEST EXTENT PERMITTED BY LAW, ANY OBJECTION WHICH IT MAY NOW OR HEREAFTER HAVE TO THE LAYING OF VENUE OF ANY SUCH LITIGATION BROUGHT IN ANY SUCH
COURT REFERRED TO ABOVE AND ANY CLAIM THAT ANY SUCH LITIGATION HAS BEEN BROUGHT IN AN INCONVENIENT FORUM. To the extent not already appointed under the Credit Agreement, each Grantor hereby appoints CT Corporation as such Grantor’s agent where
notices and demands to or upon such Grantor in respect of this Agreement, the Credit Agreement, the Intellectual Property Security Agreements or the Subsidiary Guaranties may be served (without prejudice to the right of the Agent or the Lender to
serve process in any other manner permitted by law). If for any reason such process agent is unable to serve as such, such Grantor will within 30 days appoint a substitute process agent located in the State of New York and give notice of such
appointment to the Agent. 
 18.03. WAIVER OF JURY TRIAL, ETC. EACH PARTY HERETO HEREBY WAIVES ANY RIGHT TO A TRIAL BY JURY IN ANY
ACTION OR PROCEEDING TO ENFORCE OR DEFEND ANY RIGHTS UNDER THIS AGREEMENT, ANY NOTE, ANY OTHER LOAN DOCUMENT AND ANY AMENDMENT, INSTRUMENT, DOCUMENT OR AGREEMENT DELIVERED OR WHICH MAY IN THE FUTURE BE DELIVERED IN CONNECTION HEREWITH OR THEREWITH
OR ARISING FROM ANY LENDING RELATIONSHIP EXISTING IN CONNECTION WITH ANY OF THE FOREGOING, AND AGREES THAT ANY SUCH ACTION OR PROCEEDING SHALL BE TRIED BEFORE A COURT AND NOT BEFORE A JURY. 

18.04. Counterparts. This Agreement may be executed in counterparts (and by different parties hereto in different counterparts), each
of which shall constitute an original, but all of which when taken together shall constitute a single contract. 
 18.05. Headings.
The headings of each section of this Agreement are for convenience only and shall not define or limit the provisions thereof. 

  
 32 

 18.06. No Strict Construction. The parties hereto have participated jointly in the
negotiation and drafting of this Agreement. In the event an ambiguity or question of intent or interpretation arises, this Agreement shall be construed as if drafted jointly by the parties hereto and no presumption or burden of proof shall arise
favoring or disfavoring any party by virtue of the authorship of any provisions of this Agreement. 
 18.07. Severability. The
illegality or unenforceability of any provision of this Agreement or any instrument or agreement required hereunder shall not in any way affect or impair the legality or enforceability of the remaining provisions of this Agreement or any instrument
or agreement required hereunder. 
 18.08. Survival of Agreement. All representations, warranties and agreements made by or on behalf
of any Grantor or any other Loan Party in this Agreement and in the other Loan Documents shall survive the execution and delivery hereof or thereof and the making and repayment of the Loans. In addition, notwithstanding anything herein or under
Applicable Law to the contrary, the provisions of this Agreement and the other Loan Documents relating to indemnification or payment of costs and expenses, including, without limitation, the provisions of Sections 3.1, 3.2, 3.3, 3.4 and
10.4 of the Credit Agreement, shall survive the Payment in Full of the Loans, the termination of the Commitments and any termination of this Agreement or any of the other Loan Documents. 

18.09. Fees and Expenses; Indemnification. 

(a) Subject to Section 18.12, the Grantors, agree to pay upon demand the amount of any and all reasonable expenses, including the
fees, disbursements and other charges of counsel and of any experts or agents, which (i) any Secured Creditor may incur in connection with (x) enforcing or preserving any rights under this Agreement and the other Loan Documents,
(y) the exercise, enforcement or protection of any of the rights of such Secured Creditor hereunder or (z) the failure of any Grantor to perform or observe any of the provisions hereof, and (ii) the Agent may incur in connection with
(x) the administration of this Agreement or (y) the custody or preservation of, or the sale of, collection from or other realization upon any of the Collateral. 

(b) Subject to Section 18.12, each Grantor agrees to pay, and to save the Secured Creditors harmless from, any and all
liabilities, obligations, losses, damages, penalties, actions, judgments, suits, costs, expenses or disbursements of any kind or nature whatsoever with respect to the execution, delivery, enforcement, performance and administration of this Agreement
to the extent any Borrower would be required to do so pursuant to Section 10.4 of the Credit Agreement. 
 (c) The agreements
in this Section shall survive repayment of the U.S. Guarantor Obligations or the Foreign Obligations, as applicable, and all other amounts payable under the Credit Agreement and the other Loan Documents. 

  
 33 

 18.10. Binding Effect; Several Agreement. This Agreement is binding upon each
Grantor and the Secured Creditors and their respective successors and permitted assigns, and shall inure to the benefit of the Grantors, the Secured Creditors and their respective successors and permitted assigns, except that no Grantor shall have
any right to assign or transfer its rights or obligations hereunder or any interest herein, except as specifically permitted by the Credit Agreement, without the prior written consent of the Agent (and any such assignment or transfer shall be void).

 18.11. Waivers; Amendment.  

(a) No failure or delay of the Agent in exercising any power or right hereunder shall operate as a waiver thereof, nor shall any single or
partial exercise of any such right or power, or any abandonment or discontinuance of steps to enforce such a right or power, preclude any other or further exercise thereof or the exercise of any other right or power. The rights and remedies of the
Secured Creditors hereunder and of the Secured Creditors under the Credit Agreement and other Loan Documents are cumulative and are not exclusive of any rights or remedies that they would otherwise have. No waiver of any provisions of this Agreement
or consent to any departure by any Grantor therefrom shall in any event be effective unless the same shall be permitted by paragraph (b) below, and then such waiver or consent shall be effective only in the specific instance and for the purpose
for which given. No notice to or demand on any Grantor in any case shall entitle such or any other Grantor to any other or further notice or demand in similar or other circumstances. 

(b) Neither this Agreement nor any provision hereof may be waived, amended or modified except pursuant to an agreement or agreements in
writing entered into by the Agent and each affected Grantor; provided that any provision of this Agreement imposing obligations on any Grantor may be waived by the Agent in a written instrument executed by the Agent in accordance with
Section 10.1 of the Credit Agreement. 
 18.12. Limitation of Liability. Notwithstanding anything to the contrary
contained in this Agreement or in the other Loan Documents, the parties agree that: (a) no Borrower that is a CFC (or any other Loan Party that is organized in any jurisdiction outside of the United States and is a CFC) shall be liable for any
obligation of the Parent, Vicuron, Durata U.S. (or any other Loan Party that is organized in the United States or any state or territory thereof) arising under or with respect to any of the Loan Documents; (b) neither the Agent nor any Lender
nor any Affiliate thereof, may set-off or apply any deposits of a Borrower that is a CFC (or any other Loan Party that is organized in any jurisdiction outside of the United States that is a CFC) or any other obligations at the time owing to or for
the credit of the account of any Borrower that is a CFC (or any other Loan Party that is organized in any jurisdiction outside of the United States that is a CFC), against any or all of the obligations of the Parent, Vicuron, Durata U.S. (or any
other Loan Party that is organized in the United States or any state or territory thereof), and (c) no Lien or Security Interest in any Property of a Borrower that is a CFC (or any other Loan Party that is organized in any jurisdiction outside
of the 

  
 34 

 
United States that is a CFC) shall secure any Obligations of the Parent, Vicuron, Durata U.S. (or any other Loan Party that is organized in the United States or a state or territory thereof) as a
Guarantor under this Agreement or the other Loan Documents. 
 18.13. Integration. This Agreement and the other Loan Documents
constitute the entire contract among the parties relating to the subject matter hereof and supersede any and all previous agreements and understandings, oral or written, relating to the subject matter hereof. 

18.14. Acknowledgments. Each Grantor hereby acknowledges that: 

(a) it has been advised by counsel in the negotiation, execution and delivery of this Agreement and the other Loan Documents to which it is a
party; 
 (b) no Secured Creditor has any fiduciary relationship with or duty to any Grantor arising out of or in connection with this
Agreement or any of the other Loan Documents, and the relationship between the Grantors, on the one hand, and the Secured Creditors, on the other hand, in connection herewith or therewith is solely that of debtor and creditor; and 

(c) no joint venture is created hereby or by the other Loan Documents or otherwise exists by virtue of the transactions contemplated hereby
among the Secured Creditors or among the Grantors and the Secured Creditors. 
 18.15. Additional Grantors. Each Subsidiary of any
Borrower that is required to become a party to this Agreement pursuant to Section 6.7 of the Credit Agreement shall become a Grantor for all purposes of this Agreement upon execution and delivery by such Subsidiary of an Joinder
Agreement in the form of Annex I hereto and shall concurrently therewith deliver to the Agent a Subsidiary Guaranty as required by the Credit Agreement. 

18.16. Releases. 
 (a)
Notwithstanding anything to the contrary contained in the Credit Agreement, herein or in any other Loan Document, upon request of the applicable Borrower in connection with any disposition of Property permitted by the Loan Documents, the Agent shall
(without notice to or vote or consent of any other Secured Creditor) take such actions as shall be required to release the Security Interest in any Collateral being disposed of in such disposition, to the extent necessary to permit consummation of
such disposition in accordance with the Loan Documents; provided that such Borrower shall have delivered to the Agent, at least five (5) Business Days prior to the date of the proposed release, a written request for release identifying
the relevant Collateral being disposed of in such disposition and the terms of such disposition in reasonable detail, together with a certification by such Borrower stating that such transaction is in compliance with the Credit Agreement and the
other Loan Documents and that the proceeds of such disposition will be applied in accordance with the Credit Agreement and the other Loan Documents. 

  
 35 

 (b) At the request and sole expense of any Borrower, a Grantor (other than the Borrowers) shall
be released from its obligations hereunder in the event that all the capital stock or other equity interests of such Grantor shall be disposed of in a transaction permitted by the Credit Agreement; provided that such Borrower shall have
delivered to the Agent, at least five (5) Business Days prior to the date of the proposed release, a written request for release identifying the relevant Grantor and the terms of the disposition in reasonable detail, together with a
certification by such Borrower stating that such transaction is in compliance with the Credit Agreement and the other Loan Documents and that the Proceeds of such disposition will be applied in accordance therewith. 

18.17. Intercompany Debt. 

(a) Each Grantor hereby agrees that any intercompany Debt or other intercompany payables or receivables directly or indirectly made by or
owed to such Grantor by any other Grantor (collectively, “Intercompany Debt”), of whatever nature at any time outstanding shall be subordinate and subject in right of payment to the prior payment in full in cash of the U.S.
Guarantor Obligations or the Foreign Obligations, as applicable. Each Grantor hereby agrees that following a single written notice to the Borrowers from Agent, such Grantor will not, while any Event of Default is continuing, accept any payment,
including by offset, on any Intercompany Debt until all U.S. Guarantor Obligations or the Foreign Obligations, as applicable, have been Paid in Full and the Commitments have been terminated, in each case, except with the prior written consent of the
Agent. 
 (b) In the event that any payment on any Intercompany Debt shall be received by a Grantor other than as permitted by this
Section 18.17 before all U.S. Guarantor Obligations or the Foreign Obligations, as applicable, have been Paid in Full and the Commitments have been terminated pursuant to the Credit Agreement, such Grantor shall receive such payments and
hold the same in trust for, segregate the same from its own assets and shall immediately pay over to, the Agent for the benefit of the Agent and the other Secured Creditors all such sums to the extent necessary so that the Agent and the other
Secured Creditors shall have been Paid in Full, in cash, all U.S. Guarantor Obligations or Foreign Obligations, as applicable, owed or which may become owing. 

(c) Upon any payment or distribution of any assets of any Grantor of any kind or character, whether in cash, property or securities by
set-off, recoupment or otherwise, to creditors in any liquidation or other winding-up of such Grantor or in the event of any case, proceeding or other action described in Section 8.1.3 of the Credit Agreement, the Agent and the other
Secured Creditors shall first be entitled to receive payment in full in cash, in accordance with the terms of the U.S. Guarantor Obligations or the Foreign Obligations, as applicable, and of this Agreement, of all amounts payable under or in respect
of such U.S. Guarantor Obligations or the Foreign Obligations, as applicable, before any payment or distribution is made on, or in respect of, any Intercompany Debt, in any such case, proceeding or other action, any distribution or

  
 36 

 
payment, to which the Agent or any other Secured Creditor would be entitled except for the provisions hereof shall be paid by such Grantor, or by any receiver, trustee in bankruptcy, liquidating
trustee, agent or other person making such payment or distribution directly to the Agent (for the benefit of the Agent and the other Secured Creditors) to the extent necessary to pay all such U.S. Guarantor Obligations or the Foreign Obligations, as
applicable, in full in cash, after giving effect to any concurrent payment or distribution to the Agent and other Secured Creditors (or to the Agent for the benefit of the Agent and the other Secured Creditors). 

[Remainder of Page Intentionally Left Blank; Signature Pages Follow] 

  
 37 

 IN WITNESS WHEREOF, each of the undersigned has caused this Security Agreement to be duly
executed and delivered as of the date first above written. 
  

					
	GRANTORS:
	
	 DURATA THERAPEUTICS HOLDING C.V.,

a limited partnership organized under the laws of the Netherlands

		
	By:	 	  

		 	Name:	 	
		 	Title:	 	
	
	 DURATA THERAPEUTICS INTERNATIONAL B.V.,

a private company with limited liability incorporated under the laws of the Netherlands

		
	By:	 	  

		 	Name:	 	
		 	Title:	 	
	
	 DURATA THERAPEUTICS, INC.,
 a
Delaware corporation

		
	By:	 	  

		 	Name:	 	
		 	Title:	 	
	
	 VICURON PHARMACEUTICALS INC.,

a Delaware corporation

		
	By:	 	  

		 	Name:	 	
		 	Title:	 	

 [SIGNATURE PAGE TO SECURITY
AGREEMENT] 

 
					
	 DURATA THERAPEUTICS U.S. LIMITED,

a Delaware corporation

		
	By:	 	  

		 	Name:	 	
		 	Title:	 	

 [SIGNATURE PAGE TO SECURITY
AGREEMENT] 

 
					
	AGENT:
		
		 	 PDL BIOPHARMA, INC.,
 a
Delaware corporation

		
	By:	 	  

		 	Name:	 	
		 	Title:	 	

 [SIGNATURE PAGE TO SECURITY
AGREEMENT] 

 Exhibit A to Security Agreement 

COPYRIGHT SECURITY AGREEMENT 

WHEREAS, [            ], a
[            ] (herein referred to as “Grantor”), having an address at [            ], has adopted, used and is
using the copyrights listed on the annexed Schedule 1-A, which copyrights are registered in the United States Copyright Office (the “Copyrights”); 

WHEREAS, the Grantor has entered into a Security Agreement, dated as of
[            ], 2013 (said Security Agreement, as it may hereafter be amended or otherwise modified from time to time being the “Security Agreement”, the terms defined
therein and not otherwise defined herein being used herein as therein defined) in favor of the Agent, for itself and the Lender party to the Credit Agreement (in such capacity, the “Secured Party”); and 

WHEREAS, pursuant to the Security Agreement, the Grantor has granted to Secured Party a security interest in all right, title and
interest of the Grantor in and to the Copyrights, and the registrations and recordings thereof in the United States Copyright Office or any other country or any political subdivision thereof, all whether now or hereafter owned or licensable by the
Grantor and all extensions or renewals thereof and all Copyright licenses, and all proceeds of all of the foregoing, including, without limitation, any claims by the Grantor against third parties for infringement thereof, to secure the payment and
performance of the Obligations. 
 NOW, THEREFORE, for good and valuable consideration, receipt of which is hereby acknowledged, the
Grantor does hereby further confirm, and put on the public record: 
 Section 1. Grant of Security Interest in Copyright
Collateral. Each Grantor, as collateral security for the prompt and complete payment and performance when due (whether at stated maturity, by acceleration or otherwise) of the Obligations of such Grantor, hereby mortgages, pledges and
hypothecates to the Agent for the benefit of the Secured Creditors, and grants to the Agent for the benefit of the Secured Creditors a Lien on and security interest in, all of its right, title and interest in, to and under the following Collateral
of such Grantor (the “Copyright Collateral”): 
 (i) all of its Copyrights, including, without limitation, those referred
to on Schedule 1-A hereto; 
 (ii) all renewals, reversions and extensions of the foregoing; and 

(iii) all income, royalties, proceeds and liabilities at any time due or payable or asserted under and with respect to any of the foregoing,
including, without limitation, all rights to sue and recover at law or in equity for any past, present and future infringement, misappropriation, dilution, violation or other impairment thereof. 

 Section 2. Security Agreement. The security interest granted pursuant to this
Copyright Security Agreement is granted in conjunction with the security interest granted to the Agent pursuant to the Security Agreement and each Grantor hereby acknowledges and agrees that the rights and remedies of the Agent with respect to the
security interest in the Copyright Collateral made and granted hereby are more fully set forth in the Security Agreement, the terms and provisions of which are incorporated by reference herein as if fully set forth herein. In the event of any
irreconcilable conflict between the terms of this Copyright Security Agreement and the terms of the Security Agreement, the terms of the Security Agreement shall control. 

SECTION 3. Grantor Remains Liable. Each Grantor hereby agrees that, anything herein to the contrary notwithstanding, such Grantor
shall assume responsibility for the prosecution, defense, enforcement or any other necessary or desirable actions in such Grantor’s reasonable business judgment in connection with their Copyrights subject to a security interest hereunder. 

SECTION 4. GOVERNING LAW THIS COPYRIGHT SECURITY AGREEMENT SHALL BE GOVERNED BY THE LAWS OF THE STATE OF NEW YORK. 

Section 5. Counterparts. This Copyright Security Agreement may be executed in any number of counterparts and by different parties
in separate counterparts, each of which when so executed shall be deemed to be an original and all of which taken together shall constitute one and the same agreement. Signature pages may be detached from multiple separate counterparts and attached
to a single counterpart. Delivery of a signature page of this Copyright Security Agreement by telecopy or other electronic means shall be effective as delivery of a manually executed counterpart of such Copyright Security Agreement. 

[SIGNATURE PAGES FOLLOW] 

 IN WITNESS WHEREOF, the undersigned Grantor has duly executed or caused this Copyright Security Agreement
to be duly executed as of the date first set forth above. 
  

					
	[                    ]
		
	By:	 	  

		 	Name:	 	
		 	Title:	 	

 Schedule 1-A to the COPYRIGHT SECURITY AGREEMENT

  

					
	 Copyright
	  	 Registration

Date
	  	 Registration No.

 

 Exhibit B to Security Agreement 

PATENT SECURITY AGREEMENT 

WHEREAS, [            ], a
[            ] (herein referred to as “Grantor”), having an address at [            ], owns the letters patent
and/or applications for letters patent of the United States of America more particularly described on Schedule 1-A annexed hereto as part hereof (the “Patents”); 

WHEREAS, the Grantor has entered into a Security Agreement, dated as of
[            ], 2013 (said Security Agreement, as it may hereafter be amended or otherwise modified from time to time being the “Security Agreement”, the terms defined
therein and not otherwise defined herein being used herein as therein defined) in favor of the Agent, for itself and the Lender party to the Credit Agreement (in such capacity, the “Secured Party”); and 

WHEREAS, pursuant to the Security Agreement, the Grantor has granted to Secured Party a security interest in all right, title and
interest of Grantor in and to the Patents, together with all registrations and recordings thereof, including, without limitation, applications, registrations and recordings in the United States Patent and Trademark Office or in any similar office or
agency of the United States, any State thereof or any other country or any political subdivision thereof, all whether now or hereafter owned or licensable by Grantor, and all reissues, divisions, continuations, continuations-in-part, term restorations or extensions thereof, all Patent licenses and all proceeds of all of the foregoing, including, without limitation, any claims by Grantor against third parties for
infringement thereof for the full term of the Patents, to secure the prompt payment and performance of the Obligations. 
 NOW,
THEREFORE, for good and valuable consideration, receipt of which is hereby acknowledged, the Grantor does hereby further confirm, and put on the public record, its grant to Secured Party of a security interest in and mortgage on the Collateral
to secure the prompt payment and performance of the Obligations. 
 Section 1. Grant of Security Interest in Patents 

Each Grantor hereby grants to the Agent a security interest and continuing lien on all of such Grantor’s right, title and interest in, to
and under the following, in each case whether owned or existing or hereafter acquired or arising and wherever located (collectively, the “Patent Collateral”): all United States and foreign patents and certificates of invention, or
similar industrial property rights, including, but not limited to each patent referred to in Schedule 1-A hereto (as such schedule may be amended or supplemented from time to time), and with respect to any and all of the foregoing,
(i) all applications therefor including the patent applications referred to in Schedule 1-A hereto (as such schedule may be amended or supplemented from time to time), (ii) all reissues, divisions, continuations, continuations-in-part,
extensions, renewals, and reexaminations thereof, (iii) all rights corresponding thereto throughout the world, (iv) all inventions and improvements described therein, (v) all rights to sue for past, present and future

 
infringements thereof, (vi) all licenses, claims, damages, and proceeds of suit arising therefrom, and (vii) all proceeds, payments and rights to payments arising out of the sale,
lease, license, assignment, or other disposition thereof. 
 Section 2. Security Agreement 

The security interests granted pursuant to this Patent Security Agreement are granted in conjunction with the security interests granted to
the Agent pursuant to the Security Agreement and each Grantor hereby acknowledges and affirms that the rights and remedies of the Agent with respect to the security interest in the Patent Collateral made and granted hereby are supplemental of, and
more fully set forth in, the Security Agreement, the terms and provisions of which are incorporated by reference herein as if fully set forth herein. In the event of any irreconcilable conflict between the terms of this Patent Security Agreement and
the terms of the Security Agreement, the terms of the Security Agreement shall control. 
 Section 3. Grantor Remains Liable.
Each Grantor hereby agrees that, anything herein to the contrary notwithstanding, such Grantor shall assume responsibility for the prosecution, defense, enforcement or any other necessary or desirable actions in such Grantor’s reasonable
business judgment in connection with their Patents subject to a security interest hereunder. 
 Section 4. GOVERNING LAW 

THIS PATENT SECURITY AGREEMENT SHALL BE GOVERNED BY THE LAWS OF THE STATE OF NEW YORK. 

Section 5. Counterparts.  

This Patent Security Agreement may be executed in counterparts, each of which shall constitute an original, but all of which when taken
together shall constitute a single contract. This Patent Security Agreement shall become effective when the Agent has received counterparts bearing the signatures of all parties hereto. Delivery of a signature page of this Patent Security Agreement
by telecopy or other electronic means shall be effective as delivery of a manually executed counterpart of such Patent Security Agreement. 

[SIGNATURE PAGE FOLLOWS] 

 IN WITNESS WHEREOF, the undersigned Grantor has duly executed or caused this Patent Security Agreement to
be duly executed as of the date first set forth above. 
  

					
	[                    ]
		
	By:	 	  

		 	Name:	 	
		 	Title:	 	

 Schedule 1-A to the PATENT SECURITY AGREEMENT 

 

					
	 Title
	  	 Date Filed

or Granted
	  	 Serial No. or

Patent No.

 Exhibit C to Security Agreement 

TRADEMARK SECURITY AGREEMENT 

WHEREAS, [            ], a
[            ] (herein referred to as “Grantor”), having an address at [            ], (1) has adopted,
used and is using, or (2) has intended to use and filed an application indicating that intention, but has not yet filed an allegation of use under Section l(c) or l(d) of the Trademark Act, or (3) has filed an application based on an
intention to use and has since used and has filed an allegation of use under Section l(c) or l(d) of the Trademark Act, the trademarks, trade names, trade styles and service marks listed on the annexed Schedule
1-A, which trademarks, trade names, trade styles and service marks are registered, or for which applications for registration have been filed in the United States Patent and Trademark Office (the
“Trademarks”); and 
 WHEREAS, the Grantor has entered into a Security Agreement, dated as of
[            ], 2013 (said Security Agreement, as it may hereafter be amended or otherwise modified from time to time being the “Security Agreement”, the terms defined
therein and not otherwise defined herein being used herein as therein defined) in favor of the Agent, for itself and the Lender party to the Credit Agreement (in such capacity, the “Secured Party”); and 

WHEREAS, pursuant to the Security Agreement, the Grantor has granted to Secured Party a security interest in all right, title and
interest of the Grantor in and to the Trademarks, together with all prints and labels on which said Trademarks have appeared or appear, designs and general intangibles of like nature, now existing or hereafter adopted or acquired, and the goodwill
of the business symbolized by the Trademarks and the applications, registrations and recordings in the United States Patent and Trademark Office or in any similar office or agency of the United States of America, any State thereof, or any other
country or any political subdivision thereof, all whether now or hereafter owned or licensable by Grantor, and all reissues, extensions or renewals thereof, all Trademark licenses and all proceeds of all of the foregoing, including, without
limitation, any claims by Grantor against third parties for infringement thereof, to secure the payment and performance of the Obligations. 

NOW, THEREFORE, for good and valuable consideration, receipt of which is hereby acknowledged, the Grantor does hereby further confirm,
and put on the public record: 
 Section 1. Grant of Security Interest in Trademarks. 

Each Grantor hereby grants to the Agent a security interest and continuing lien on all of such Grantor’s right, title and interest in, to
and under the following, in each case whether owned or existing or hereafter acquired or arising and wherever located (collectively, the “Trademark Collateral”): 

(i) all United States, State and foreign trademarks, service marks, certification marks, collective marks, trade names,
corporate names, d/b/as, business names, fictitious business names, Internet domain names, trade styles, logos, other source or business identifiers, designs and general intangibles of a like nature and, with respect to any and all of the foregoing:
(i) all registrations and applications therefor including, but not limited to, the registrations and applications referred to in Schedule 1-A hereto (as such schedule may be amended or supplemented from time to time), 

 (ii) the goodwill of the business symbolized thereby, 

(iii) all rights corresponding thereto throughout the world, 

(iv) all rights to sue for past, present and future infringement or dilution thereof or for any injury to goodwill, 

(v) all licenses, claims, damages, and proceeds of suit arising therefrom, and 

(vi) all payments and rights to payments arising out of the sale, lease, license assignment or other disposition thereof; 

provided that the security interest granted under Section 2 hereof shall not attach to, and the term “Trademark
Collateral” shall not include any applications for trademark filed in the United States Patent and Trademark Office pursuant to 15 U.S.C. § 1051 Section 1(b), only to the extent that the grant of a security interest therein would
result in the abandonment, invalidation or unenforceability of the trademarks matured from such application or rights hereunder and only until evidence of the use of such trademarks in commerce, as defined in 15 U.S.C. Section 1127, is
submitted to, and accepted by, the United States Patent and Trademark Office pursuant to 15 U.S.C. § 1051 Section 1(c) or 1(d), following which filing all such applications shall automatically become Trademark Collateral. 

Section 2. Security Agreement 

The security interests granted pursuant to this Trademark Security Agreement are granted in conjunction with the security interests granted to
the Agent pursuant to the Security Agreement and each Grantor hereby acknowledges and affirms that the rights and remedies of the Agent with respect to the security interest in the Trademark Collateral made and granted hereby are supplemental of,
and more fully set forth in, the Security Agreement, the terms and provisions of which are incorporated by reference herein as if fully set forth herein. In the event of any irreconcilable conflict between the terms of this Trademark Security
Agreement and the terms of the Security Agreement, the terms of the Security Agreement shall control. 
 Section 3. Grantor Remains
Liable. Each Grantor hereby agrees that, anything herein to the contrary notwithstanding, such Grantor shall assume responsibility 

 
for the prosecution, defense, enforcement or any other necessary or desirable actions in such Grantor’s reasonable business judgment in connection with their Trademarks subject to a security
interest hereunder. 
 Section 4. GOVERNING LAW 

THIS TRADEMARK SECURITY AGREEMENT SHALL BE GOVERNED BY THE LAWS OF THE STATE OF NEW YORK. 

Section 5. Counterparts. 

This Trademark Security Agreement may be executed in counterparts, each of which shall constitute an original, but all of which when taken
together shall constitute a single contract. This Trademark Security Agreement shall become effective when the Agent has received counterparts bearing the signatures of all parties hereto. Delivery of a signature page of this Trademark Security
Agreement by telecopy or other electronic means shall be effective as delivery of a manually executed counterpart of such Trademark Security Agreement. 

[SIGNATURE PAGE FOLLOWS] 

 IN WITNESS WHEREOF, the undersigned Grantor has duly executed or caused this Trademark Security Agreement
to be duly executed as of the date first set forth above. 
  

					
	[                    ]
		
	By:	 	  

		 	Name:	 	
		 	Title:	 	

 Schedule 1-A to the TRADEMARK SECURITY AGREEMENT

  

					
	 Trademark
	 	 Application or

Registration

Date
	 	 Application Serial

No. or Registration

No.

 Exhibit D to Security Agreement 

FORM OF CONTROL AGREEMENT 

This CONTROL AGREEMENT (as amended, supplemented or otherwise modified from time to time, this “Control Agreement”) dated as
of             , 20     is made by and among             , a
            (the “Grantor”), [            ], as Agent (in such capacity, the “Agent”) for the
Secured Creditors (as defined in the Security Agreement referred to below), and             , a             corporation (the
“Issuer”). 
 WHEREAS, the Grantor has granted to the Agent for the benefit of the Secured Creditors a security
interest in the uncertificated securities of the Issuer owned by the Grantor from time to time (collectively, the “Pledged Securities”), and all additions thereto and substitutions and Proceeds thereof (collectively, with the
Pledged Securities, the “Collateral”) pursuant to a Security Agreement, dated as of [            ], 2013 (as amended, supplemented, replaced or otherwise modified from time
to time, the “Security Agreement”), by the Grantor and the other persons party thereto as grantors in favor of the Agent. 

WHEREAS, the following terms which are defined in Articles 8 and 9 of the Uniform Commercial Code in effect in the State of New York on
the date hereof (the “UCC”) are used herein as so defined (whether or not such terms are capitalized in the UCC): Adverse Claim, Control, Instruction, Issuer’s Jurisdiction, Proceeds and Uncertificated Security. 

NOW, THEREFORE, for good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto
agree as follows: 
 SECTION 1. Notice of Security Interest. The Grantor, the Agent and the Issuer are entering into this Control
Agreement to perfect, and to confirm the priority of, the Agent’s security interest in the Collateral. The Issuer acknowledges that this Control Agreement constitutes written notification to the Issuer of the Agent’s security interest in
the Collateral. The Issuer agrees to promptly make all necessary entries or notations in its books and records to reflect the Agent’s security interest in the Collateral and, upon request by the Agent, to register the Agent as the registered
owner of any or all of the Pledged Securities. The Issuer acknowledges that the Agent has control over the Collateral. 
 SECTION 2.
Collateral. The Issuer hereby represents and warrants to, and agrees with the Grantor and the Agent that (i) the terms of any limited liability company interests or partnership interests, in any limited liability company or partnership
organized under the laws of the United States or any state thereof, included in the Collateral from time to time shall expressly provide that they are securities governed by Article 8 of the Uniform Commercial Code in effect from time to time in the
State of [            ], (ii) the Pledged Securities are Uncertificated Securities, (iii) the Issuer’s 

 
Jurisdiction is, and during the term of this Control Agreement shall remain, the State of [            ], (iv) Schedule 1
contains a true and complete description of the Pledged Securities as of the date hereof and (v) except for the claims and interests of the Agent and the Grantor in the Collateral, the Issuer does not know of any claim to or security interest
or other interest in the Collateral. 
 SECTION 3. Control. The Issuer hereby agrees, upon written direction from the Agent and
without further consent from the Grantor, (a) to comply with all Instructions and directions of every kind originated by the Agent concerning the Collateral, to liquidate or otherwise dispose of the Collateral as and to the extent directed by
the Agent and to pay over to the Agent all Proceeds of the Collateral without any setoff or deduction, and (b) except as otherwise directed by the Agent, not to comply with the Instructions or directions of any kind originated by the Grantor or
any other person with respect to the Collateral. 
 SECTION 4. Other Agreements. The Issuer shall notify promptly the Agent and the
Grantor if any other person asserts any lien, encumbrance, claim (including any adverse claim) or security interest in or against any of the Collateral. In the event of any conflict between the provisions of this Control Agreement and any other
agreement governing the Pledged Securities or the Collateral, the provisions of this Control Agreement shall control. 
 SECTION 5.
Protection of Issuer. The Issuer may rely and shall be protected in acting upon any notice, instruction or other communication that it reasonably believes to be genuine and authorized. 

SECTION 6. Termination. This Control Agreement shall terminate automatically upon receipt by the Issuer of written notice executed by
the Agent terminating this Agreement. 
 SECTION 7. Notices. All notices, requests and demands to or upon the respective parties
hereto to be effective shall be in writing (including by telecopy), and, unless otherwise expressly provided herein, shall be deemed to have been duly given or made when delivered, or three days after being deposited in the mail, postage prepaid,
or, in the case of telecopy notice, when received, to the Grantor’s and the Agent’s addresses as set forth in the Security Agreement, and to the Issuer’s address as set forth below, or to such other address as any party may give to
the others in writing for such purpose: 
  

					
	[Name of Issuer]	 	
	[Address of Issuer]	 	
	Attention:	 	  
	 	
	Telephone: (    )	 	  
	 	
	Telecopy: (    )	 	  
	 	

 SECTION 8. Amendments in Writing. None of the terms or provisions of this Control
Agreement may be waived, amended, supplemented or otherwise modified except by a written instrument executed by the parties hereto. 

SECTION 9. Entire Agreement. This Control Agreement and the Security Agreement constitute the entire agreement and supersede all other
prior agreements and understandings, both written and oral, among the parties with respect to the subject matter hereof. 
 SECTION 10.
Execution in Counterparts. This Control Agreement may be executed in any number of counterparts (including by telecopy or other electronic commission), each of which when so executed shall be deemed to be an original and all of which taken
together shall constitute one and the same agreement. 
 SECTION 11. Successors and Assigns. This Control Agreement will be binding
upon and inure to the benefit of the parties hereto and their respective successors and assigns, except that the Grantor may not assign, transfer or delegate any of its rights or obligations under this Control Agreement without the prior written
consent of the Agent. 
 SECTION 12. Governing Law and Jurisdiction. This Control Agreement has been delivered to and accepted by the
Agent and will be deemed to be made in the State of New York. THIS CONTROL AGREEMENT SHALL BE GOVERNED BY, AND CONSTRUED AND INTERPRETED IN ACCORDANCE WITH, THE LAW OF THE STATE OF NEW YORK. Each of the parties hereto submits for itself and its
property in any legal action or proceeding relating to this Control Agreement, or for recognition and enforcement of any judgment in respect thereof, to the exclusive general jurisdiction of the Courts of the State of New York, the courts of the
United States of America for the Southern District of New York, and appellate courts from any thereof. 
 SECTION 13. WAIVER OF JURY
TRIAL. EACH OF THE PARTIES HERETO HEREBY IRREVOCABLY AND UNCONDITIONALLY WAIVES TRIAL BY JURY IN ANY LEGAL ACTION OR PROCEEDING RELATING TO THIS CONTROL AGREEMENT AND FOR ANY COUNTERCLAIM THEREIN. 

IN WITNESS WHEREOF, each of the undersigned has caused this Control Agreement to be duly executed and delivered as of the date first above
written. 
  

			
	[NAME OF GRANTOR]
		
	By:	 	  

	Name:	 	
	Title:	 	
	[            ], as

 
			
	Agent
		
	By:	 	  

	Name:	 	
	Title:	 	
	
	[NAME OF ISSUER]
		
	By:	 	  

	Name:	 	
	Title:	 	

 Annex I to Security Agreement 

JOINDER AGREEMENT, dated as of             , 20    , made by
            , a             (the “Additional Grantor”), in favor of
[            ], as Agent (in such capacity, the “Agent”) for (i) the lender (the “Lender”) party to the Credit Agreement referred to below and
(ii) the other Secured Creditors (as defined in the Security Agreement (as hereinafter defined)). All capitalized terms not defined herein shall have the meaning ascribed to them in such Credit Agreement. 

W I T N E S S E T H: 

WHEREAS,            (the “Borrower”), the Lender and the Agent
have entered into the Credit Agreement, dated as of [            ], 2013 (as amended, supplemented, replaced or otherwise modified from time to time, the “Credit
Agreement”); 
 WHEREAS, in connection with the Credit Agreement, the Borrower has entered into a Security Agreement, dated as of
[            ], 2013 (as amended, supplemented or otherwise modified from time to time, the “Security Agreement”) in favor of the Agent for the benefit of the Secured
Creditors; 
 WHEREAS, the Credit Agreement requires the Additional Grantor to become a party to the Security Agreement; and 

WHEREAS, the Additional Grantor has agreed to execute and deliver this Joinder Agreement in order to become a party to the Security Agreement;

 NOW, THEREFORE, IT IS AGREED: 

1. Security Agreement. By executing and delivering this Joinder Agreement, the Additional Grantor, as provided in
Section 18.15 of the Security Agreement, hereby becomes a party to the Security Agreement as a Grantor thereunder with the same force and effect as if originally named therein as a Grantor and, without limiting the generality of the
foregoing, hereby expressly assumes all obligations and liabilities of a Grantor thereunder. The information set forth in Annex I-A hereto is hereby added to the information set forth in the Perfection Certificate or Perfection Supplement
most recently delivered pursuant to the terms of the Security Agreement. The Additional Grantor hereby represents and warrants that each of the representations and warranties as to the Additional Grantor contained in Section 5 of the
Security Agreement is true and correct in all respects on and as the date hereof (after giving effect to this Joinder Agreement) as if made on and as of such date. 

2. GOVERNING LAW. THIS JOINDER AGREEMENT SHALL BE GOVERNED BY, AND CONSTRUED AND INTERPRETED IN ACCORDANCE WITH, THE LAW OF THE STATE
OF NEW YORK. 
 IN WITNESS WHEREOF, the undersigned has caused this Joinder Agreement to be duly executed and delivered as of the date first
above written. 

 
			
	[ADDITIONAL GRANTOR]
		
	By:	 	  

		 	Name:
		 	Title:

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