Document:

Exhibit 10.47

 

SECOND
AMENDMENT TO

STEMONIX, INC.

2015 STOCK OPTION PLAN

THIS
SECOND AMENDMENT TO STEMONIX, INC. 2015 STOCK OPTION PLAN (this “Amendment”) is made effective as December 12,
2019.

 

RECITALS

 

A.
StemoniX, Inc., a Minnesota corporation (the “Company”) adopted that certain 2015 Stock Option Plan (the “Plan”)
as of May 4, 2015, as amended by that certain First Amendment, dated as of February 17, 2017.

 

B.
Section 8 of the Plan permits the Board of Directors of the Company (the “Board”) to amend the Plan.

 

C.
On the date hereof, the Board approved an amendment to the Plan to increase by 500,000 the number of shares issuable under the
Plan.

 

NOW,
THEREFORE, in consideration of the foregoing and for other good and valuable consideration, the receipt and sufficiency of
which are hereby acknowledged, the Plan is hereby amended as follows:

 

1.
Shares Subject to Plan. Section
5.3(a) of the Plan is hereby amended and restated in its entirety to read as follows:

 

Subject
to the following provisions of this Section 5.3, the maximum aggregate number of shares of Stock that may be issued and sold under
the Plan shall be 1,177,338 shares. The shares of Stock may be authorized, but unissued, or reacquired Stock.

 

2.
Remaining Terms. Except as expressly
set forth in this Amendment, all other terms and provisions of the Plan shall remain in full force and effect.

 

3.
Governing Law. This Amendment and
the rights of the parties hereunder will be governed by, interpreted, and enforced in accordance with the internal laws, without
regard to the law pertaining to choice or conflict of laws, of the State of Minnesota.

 

4.
Method of Execution. This Amendment
may be executed by pdf or other facsimile.

 

5.
Binding Effect. This Amendment
shall be binding upon the Company and recipients of awards under the Plan, and their respective successors and permitted assigns.

 

[SIGNATURE
PAGE FOLLOWS]

 

    	 

     

    

 

IN
WITNESS WHEREOF, the undersigned has executed this Amendment as of the date first written above.

 

	 	StemoniX, Inc.
	 	 	 
	 	By:	/s/
    Yung-Ping Yeh 
	 	Name:
    	Yung-Ping
    Yeh
	 	Its:	Chief
    Executive OfficerExhibit 10.48

 

THIRD
AMENDMENT TO

STEMONIX, INC.

2015 STOCK OPTION PLAN

THIS
THIRD AMENDMENT TO STEMONIX, INC. 2015 STOCK OPTION PLAN (this “Amendment”) is made effective as July 31,
2020.

 

RECITALS

 

A.
StemoniX, Inc., a Minnesota corporation (the “Company”) adopted that certain 2015 Stock Option Plan (the “Plan”)
as of May 4, 2015, as amended by that certain First Amendment, dated as of February 17, 2017, and as further amended by that certain
Second Amendment, dated as of December 12, 2019.

 

B.
Section 8 of the Plan permits the Board of Directors of the Company (the “Board”) to amend the Plan.

 

C.
On the date hereof, the Board approved an amendment to the definition of “Change in Control” as defined in Section
1.4 of the Plan to add a clarifying sentence at the end of the definition of “Change in Control.”

 

NOW,
THEREFORE, in consideration of the foregoing and for other good and valuable consideration, the receipt and sufficiency of
which are hereby acknowledged, the Plan is hereby amended as follows:

 

1.
Change in Control. Section 1.4
of the Plan is hereby amended and restated in its entirety to read as follows:

 

The
term “Change in Control” shall mean:

 

(a)
the acquisition by any person or group deemed a person under Sections 3(a)(9) and 13(d)(3) of the Exchange Act (other than the
Company and its subsidiaries as determined immediately prior to that date) of beneficial ownership, directly or indirectly (with
beneficial ownership determined as provided in Rule 13d-3, or any successor rule, under the Exchange Act), of a majority of the
total combined voting power of all classes of Stock of the Company having the right under ordinary circumstances to vote at an
election of the Board, if such person or group deemed a person prior to such acquisition was not a beneficial owner of at least
five percent (5%) of such total combined voting power of the Company;

 

    	 

     

    

 

(b)
the merger or consolidation of the Company with another corporation or other entity where (i) shareholders of the Company immediately
prior to such merger or consolidation would not beneficially own following such merger or consolidation shares entitling such
shareholders to a majority of all votes (without consolidation of the rights of any class of stock to elect directors by a separate
class vote) to which all shareholders of the surviving corporation would be entitled in the election of directors, or (ii) where
the members of the Board, immediately prior to such merger or consolidation, would not, immediately after such merger or consolidation,
constitute a majority of the board of directors of the surviving corporation; or

 

(c)
the sale of all or substantially all of the assets of the Company.

 

For
the avoidance of doubt, notwithstanding anything to the contrary herein, a “Change in Control” shall not include a
transaction or series of transactions following which the shareholders of the Company as of immediately prior to such transaction
or series of transactions hold a majority of the voting power of the continuing or surviving entity, or of an entity controlling
the continuing or surviving entity, immediately after such transaction or series of transactions.

 

2.
Remaining Terms. Except as expressly
set forth in this Amendment, all other terms and provisions of the Plan shall remain in full force and effect.

 

3.
Governing Law. This Amendment and
the rights of the parties hereunder will be governed by, interpreted, and enforced in accordance with the internal laws, without
regard to the law pertaining to choice or conflict of laws, of the State of Minnesota.

 

4.
Method of Execution. This Amendment
may be executed by pdf or other facsimile.

 

5.
Binding Effect. This Amendment
shall be binding upon the Company and recipients of awards under the Plan, and their respective successors and permitted assigns.

 

[SIGNATURE
PAGE FOLLOWS]

 

    	 

     

    

 

IN
WITNESS WHEREOF, the undersigned has executed this Amendment as of the date first written above.

 

	 	StemoniX,
    Inc.
	 	 	 
	 	By:
    	/s/
    Yung-Ping Yeh
	 	Name:	Yung-Ping
    Yeh
	 	Its:
    	Chief
    Executive OfficerExhibit 10.49

 

FOURTH
AMENDMENT TO

STEMONIX, INC.

2015 STOCK OPTION PLAN

THIS
FOURTH AMENDMENT TO STEMONIX, INC. 2015 STOCK OPTION PLAN (this “Amendment”) is made effective as of August 19,
2020.

 

RECITALS

 

A.
StemoniX, Inc., a Minnesota corporation (the “Company”) adopted that certain 2015 Stock Option Plan (the “Plan”)
as of May 4, 2015, as amended by that certain First Amendment, dated as of February 17, 2017, as further amended by that certain
Second Amendment, dated as of December 12, 2019 and as further amended by that certain Third Amendment, dated as of July 31, 2020.

 

B.
Section 8 of the Plan permits the Board of Directors of the Company (the “Board”) to amend the Plan.

 

C.
On the date hereof, the Board approved an amendment to the Plan to (i) state the maximum number of shares that may be issued in
respect of Incentive Stock Options (as defined in the Plan) under the Plan and (ii) clarify the effects of certain changes in
corporate structure as set forth in Section 5.3(c) of the Plan.

 

NOW,
THEREFORE, in consideration of the foregoing and for other good and valuable consideration, the receipt and sufficiency of
which are hereby acknowledged, the Plan is hereby amended as follows:

 

1.
Section 5.3 of the Plan is hereby amended and
restated in its entirety to read as follows:

 

(a)
Subject to the following provisions of this Section 5.3, the maximum aggregate number of shares of Stock that may be issued and
sold under the Plan shall be 1,177,338 shares, 1,060,250 of which may, but need not, be issued in respect of Incentive Stock Options.
The shares of Stock may be authorized, but unissued, or reacquired Stock.

 

(b)
To the extent an Award terminates without having been exercised, or shares awarded are forfeited, such shares shall again be available
issue under the Plan. Shares of Stock surrendered in payment of the Exercise Price and shares of Stock which are withheld in order
to satisfy federal, state or local tax liability, shall not count against the maximum aggregate number of shares authorized to
be issued pursuant to this Plan, and shall again be available for issuance pursuant to the terms of the Plan.

 

    	 

     

    

 

(c)
In the event of any merger, reorganization, consolidation, recapitalization, stock dividend, stock split, combination or reverse
stock split, spin-off, split-up, split-off, distribution of assets or other change in corporate structure affecting the Stock,
a substitution or adjustment, as may be determined to be appropriate by the Board in its sole discretion, shall be made in the
aggregate number of shares reserved for issuance under the Plan. However, no such adjustment shall exceed the aggregate value
of any outstanding Award prior to such substitution or adjustment. In furtherance of the foregoing, a Stock Option and this Plan
may assumed by an acquirer of or successor-in-interest to the Company and in such an event, any assumed Stock Option shall be
converted into the right to purchase shares of stock of such acquirer or successor-in-interest. In addition, upon an event described
herein, the Board shall make an appropriate adjustment in the number of shares and the per-share option price of any options outstanding,
but not yet exercised. The Board may make such other adjustments as it deems appropriate.

 

2.
Remaining Terms. Except as expressly
set forth in this Amendment, all other terms and provisions of the Plan shall remain in full force and effect.

 

3.
Governing Law. This Amendment and
the rights of the parties hereunder will be governed by, interpreted, and enforced in accordance with the internal laws, without
regard to the law pertaining to choice or conflict of laws, of the State of Minnesota.

 

4.
Method of Execution. This Amendment
may be executed by pdf or other facsimile.

 

5.
Binding Effect. This Amendment
shall be binding upon the Company and recipients of awards under the Plan, and their respective successors and permitted assigns.

 

[SIGNATURE
PAGE FOLLOWS]

 

    	 

     

    

 

IN
WITNESS WHEREOF, the undersigned has executed this Amendment as of the date first written above.

 

	 	StemoniX, Inc.
	 	 	 
	 	By:
    	/s/
    Yung-Ping Yeh
	 	Name:	Yung-Ping
    Yeh
	 	Its:
    	Chief
    Executive Officer

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