Document:

Prepared by R.R. Donnelley Financial -- Form of Subscription Agreement under the 2003 Employee Stock Purchase Plan

 EXHIBIT 10.4B 
  
 SAMPLE SUBSCRIPTION AGREEMENT 
  
 TERCICA, INC. 
  
 2003 EMPLOYEE STOCK PURCHASE PLAN 
  
 SUBSCRIPTION AGREEMENT 
  

	              Original Application
	  	Offering Date:             
	              Change in Payroll Deduction Rate
	  	 
	              Change of Beneficiary(ies)
	  	 

  

	1.	 	                         hereby elects to participate
in the Tercica, Inc. 2003 Employee Stock Purchase Plan (the “Plan”) and subscribes to purchase shares of the Company’s Common Stock in accordance with this Subscription Agreement and the Plan. 

  

	2.	 	I hereby authorize payroll deductions from each paycheck in the amount of         % of my Compensation on each payday (from 0 to 10%)
during the Offering Period in accordance with the Plan. (Please note that no fractional percentages are permitted.) 

  

	3.	 	I understand that said payroll deductions shall be accumulated for the purchase of shares of Common Stock at the applicable Purchase Price determined in accordance with the Plan. I
understand that if I do not withdraw from an Offering Period, any accumulated payroll deductions will be used to automatically exercise my option. 

  

	4.	 	I have received a copy of the complete Plan. I understand that my participation in the Plan is in all respects subject to the terms of the Plan. I understand that my ability to
exercise the option under this Subscription Agreement is subject to shareholder approval of the Plan. 

  

	5.	 	Shares of Common Stock purchased for me under the Plan should be issued in the name(s) of Employee or Employee and Spouse only. 

  

	6.	 	I understand that if I dispose of any shares received by me pursuant to the Plan within 2 years after the Offering Date (the first day of the Offering Period during which I
purchased such shares) or one year after the Exercise Date, I will be treated for federal income tax purposes as having received ordinary income at the time of such disposition in an amount equal to the excess of the fair market value of the shares
at the time such shares were purchased by me over the price which I paid for the shares. I hereby agree to notify the Company in writing within 30 days after the date of any disposition of my shares and I will make adequate provision for Federal,
state or other tax withholding obligations, if any, which arise upon the disposition of the Common Stock. The Company may, but will not be obligated to, withhold 

	    	 	from my compensation the amount necessary to meet any applicable withholding obligation including any withholding necessary to make available to the Company any tax deductions or
benefits attributable to sale or early disposition of Common Stock by me. If I dispose of such shares at any time after the expiration of the 2-year and 1-year holding periods, I understand that I will be treated for federal income tax purposes as
having received income only at the time of such disposition, and that such income will be taxed as ordinary income only to the extent of an amount equal to the lesser of (1) the excess of the fair market value of the shares at the time of such
disposition over the purchase price which I paid for the shares, or (2) 15% of the fair market value of the shares on the first day of the Offering Period. The remainder of the gain, if any, recognized on such disposition will be taxed as capital
gain. 

  

	7.	 	I hereby agree to be bound by the terms of the Plan. The effectiveness of this Subscription Agreement is dependent upon my eligibility to participate in the Plan.

  

	8.	 	In the event of my death, I hereby designate the following as my beneficiary(ies) to receive all payments and/or shares due me under the Plan: 

  

	 NAME: (Please print)
	 	  

	 	 	(First)	 	(Middle)	 	(Last)
	  

	 	  

	 Relationship
	 	 	 	 	 	 
	  

	 	  

	 Percentage Benefit
	 	(Address)	 	 	 	 
		
	 NAME: (please print)
	 	  

	 	 	(First)	 	(Middle)	 	(Last)
	  

	 	  

	 Relationship
	 	 	 	 	 	 
	  

	 	  

	 Percentage of Benefit
	 	(Address)	 	 	 	 

  

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	 Employee’s Social
 Security Number:
	 	 	 	 
	 	
	 	 
	 Employee’s Address:
	 	 	 	 
	 	
	 	 
	 	 	 	 	 
	 	
	 	 
	 	 	 	 	 
	 	
	 	 

  
 I UNDERSTAND THAT THIS SUBSCRIPTION
AGREEMENT SHALL REMAIN IN EFFECT THROUGHOUT SUCCESSIVE OFFERING PERIODS UNLESS TERMINATED BY ME. 
  

	 Dated:
	  	  

	  	 	  	  

	 	  	 	  	 	  	Signature of Employee
				
	 	  	 	  	 	  	  

	 	  	 	  	 	  	Spouse’s Signature (If beneficiary other than spouse)

  

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 SAMPLE WITHDRAWAL NOTICE 
  
 TERCICA, INC. 
  
 2003 EMPLOYEE STOCK PURCHASE PLAN 
  
 NOTICE OF WITHDRAWAL 
  
 The undersigned participant in the Offering Period of the Tercica, Inc. 2003 Employee Stock Purchase Plan which began on
                        ,          (the “Offering Date”) hereby
notifies the Company that he or she hereby withdraws from the Offering Period. He or she hereby directs the Company to pay to the undersigned as promptly as practicable all the payroll deductions credited to his or her account with respect to such
Offering Period. The undersigned understands and agrees that his or her option for such Offering Period will be automatically terminated. The undersigned understands further that no further payroll deductions will be made for the purchase of shares
in the current Offering Period and the undersigned shall be eligible to participate in succeeding Offering Periods only by delivering to the Company a new Subscription Agreement. 
  

	 Name and Address of Participant:

	
	
  

  

	
	 Signature:

	  

		
	 Date:Prepared by R.R. Donnelley Financial -- Form of Indemnification Agreement

 EXHIBIT 10.5 
  
 TERCICA MEDICA, INC. 
  
 INDEMNIFICATION AGREEMENT 
  
 This Indemnification Agreement (“Agreement”) is made as of
                , by and between Tercica Medica, Inc., a Delaware corporation (the “Company”), and (“Indemnitee”). 
  
 Recitals 
  
 A.    The Company desires to attract and retain qualified directors, officers, employees and other
agents, and to provide them with protection against liability and expenses incurred while acting in that capacity; 
  
 B.    The Certificate of Incorporation and Bylaws of the Company contain provisions for indemnifying directors and officers of the
Company, and the Certificate of Incorporation, Bylaws and Delaware law contemplate that separate contracts may be entered into between the Company and its directors and officers, employees and other agents with respect to their indemnification by
the Company, which contracts may provide greater protection than is afforded by the Certificate of Incorporation and Bylaws; 
  
 C.    The Company understands that Indemnitee has reservations about serving or continuing to serve the Company without adequate
protection against personal liability arising from such service, and that it is also of critical importance to Indemnitee that adequate provision be made for advancing costs and expenses of legal defense; and 
  
 D.    The Board of Directors of the Company has approved
as being in the best interests of the Company indemnity contracts substantially in the form of this Agreement for directors and officers of the Company and its subsidiaries and for certain other employees and agents of the Company designated by the
Board of Directors. 
  
 NOW, THEREFORE, in order to induce
Indemnitee to serve or to continue to serve as a director and/or officer of the Company, and in consideration of Indemnitee’s service to the Company, the parties agree as follows: 
  
 1.    Contractual Indemnity.    In addition to the indemnification provisions
of the Certificate of Incorporation and Bylaws of the Company, the Company hereby agrees, subject to the limitations of Sections 2 and 5 hereof: 
  
 (a)    To indemnify, defend and hold Indemnitee harmless to the greatest extent possible under applicable law from and
against any and all judgments, fines, penalties, amounts paid in settlement and any other amounts reasonably incurred or suffered by Indemnitee (including attorneys’ fees) in connection with any threatened, pending or completed action, suit or
proceeding, whether civil, criminal, administrative or investigative, including an action by or in the right of the Company, to which Indemnitee is, was or at any time becomes a party, or is threatened to be made a 

 
party, by reason of the fact that Indemnitee is, was or at any time becomes a director, officer, employee or agent of the Company or is or was serving or at
any time serves at the request of the Company as a director, officer, employee or agent of another corporation, partnership, joint venture, trust or other enterprise (collectively referred to hereafter as a “Claim”), whether or not arising
prior to the date of this Agreement. 
  
 (b)    To pay any and all expenses reasonably incurred by Indemnitee in defending any Claim or Claims (including reasonable attorneys’ fees and other reasonable costs of investigation and defense), as the same are
incurred and in advance of the final disposition of any such Claim or Claims, upon receipt of an undertaking by or on behalf of Indemnitee to reimburse such amounts if it shall be ultimately determined that Indemnitee (i) is not entitled to be
indemnified by the Company under this Agreement, and (ii) is not entitled to be indemnified by the Company under the Certificate of Incorporation or the Bylaws of the Company or under applicable law. 
  
 The termination of any action or proceeding by judgment,
order, settlement, conviction, or upon a plea of nolo contendere or its equivalent, shall not, of itself, create a presumption that (i) Indemnitee did not act in good faith and in a manner which Indemnitee reasonably believed to be in the
best interests of the Company, or (ii) with respect to any criminal action or proceeding, Indemnitee had reasonable cause to believe that Indemnitee’s conduct was unlawful. 
  
 2.    Limitations on Contractual Indemnity.    Indemnitee shall not be
entitled to indemnification or advancement of expenses under Section 1: 
  
 (a)    if a court of competent jurisdiction, by final judgment or decree, shall determine that (i) the Claim or Claims in respect of which indemnity is sought arise from Indemnitee’s
fraudulent, dishonest or willful misconduct, or (ii) such indemnity is not permitted under applicable law; or 
  
 (b)    on account of any suit in which judgment is rendered for an accounting of profits made from the purchase or
sale by Indemnitee of securities of the Company in violation of the provisions of Section 16(b) of the Securities Exchange Act of 1934 and amendments thereto or similar provisions of any federal, state or local statutory law; or 
  
 (c)    for any acts or omissions or
transactions from which a director may not be relieved of liability under the Delaware General Corporation Law; or 
  
 (d)    with respect to proceedings or claims initiated or brought voluntarily by Indemnitee and not by way of defense,
except (i) with respect to proceedings brought in good faith to establish or enforce a right to indemnification under this Agreement or any other statute or law, or (ii) at the Company’s discretion, in specific cases if the Board of Directors
of the Company has approved the initiation or bringing of such suit; or 
  
 (e)    for expenses or liabilities of any type whatsoever (including, but not limited to, judgments, fines, ERISA excise taxes or penalties, and amounts paid in settlement) which have been paid
directly to Indemnitee by an insurance carrier under a policy of directors’ and officers’ liability insurance maintained by the Company; or 
  

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 (f)    on account of any suit brought against Indemnitee for misuse
or misappropriation of non-public information, or otherwise involving Indemnitee’s status as an “insider” of the Company, in connection with any purchase or sale by Indemnitee of securities of the Company. 
  
 3.    Continuation of Contractual
Indemnity.    Subject to the termination provisions of Section 11, all agreements and obligations of the Company contained herein shall continue for so long as Indemnitee shall be subject to any possible action, suit,
proceeding or other assertion of a Claim or Claims. 
  
 4.    Expenses; Advancement Procedure.    The Company shall advance all expenses incurred by Indemnitee in connection with the investigation, defense, settlement or appeal of any civil or
criminal action or proceeding referenced in Section 1 hereof (it being understood that amounts actually paid in settlement of any such action or proceeding shall not be treated as expenses under this Agreement). Indemnitee hereby undertakes to repay
such amounts advanced if, and to the extent that, it shall ultimately be determined that Indemnitee is not entitled to be indemnified by the Company as authorized hereby. The advances to be made hereunder shall be paid by the Company to Indemnitee
within twenty (20) days following receipt by the Company of a written request therefor from Indemnitee. 
  
 5.    Notification and Defense of Claim.    If any action, suit, proceeding or other Claim is brought
against Indemnitee in respect of which indemnity may be sought under this Agreement: 
  
 (a)    Indemnitee will promptly notify the Company in writing of the commencement thereof, and the Company and any
other indemnifying party similarly notified will be entitled to participate therein at its own expense or to assume the defense thereof and to employ counsel reasonably satisfactory to Indemnitee. Notice to the Company shall be directed to the Chief
Executive Officer of the Company at the address shown on the signature page of this Agreement (or such other address as the Company shall designate in writing to Indemnitee). Notice shall be deemed received three (3) business days after the date
postmarked if sent by domestic certified or registered mail, properly addressed; otherwise notice shall be deemed received when such notice shall actually be received by the Company. Indemnitee shall have the right to employ its own counsel in
connection with any such Claim and to participate in the defense thereof, but the fees and expenses of such counsel shall be at the expense of Indemnitee unless (i) the Company shall not have assumed the defense of the Claim and employed counsel for
such defense, or (ii) the named parties to any such action (including any impleaded parties) include both Indemnitee and the Company, and Indemnitee shall have reasonably concluded that joint representation is inappropriate under applicable
standards of professional conduct due to a material conflict of interest between Indemnitee and the Company, in either of which events the reasonable fees and expenses of such counsel to the Indemnitee shall be borne by the Company upon receipt by
the Company of the undertaking referred to in subparagraph (b) of Section 1. However, in no event will the Company be obligated to pay the fees or expenses of more than one firm of attorneys representing Indemnitee and any other agents of the
Company in connection with any one Claim or separate but substantially similar or related Claims in the same jurisdiction arising out of the same general allegations or circumstances. 
  

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 (b)    The Company shall not be liable to indemnify Indemnitee for
any amounts paid in settlement of any Claim effected without the Company’s written consent, and the Company shall not settle any Claim in a manner which would impose any penalty or limitation on Indemnitee without Indemnitee’s written
consent; provided, however, that neither the Company nor Indemnitee will unreasonably withhold its consent to any proposed settlement and, provided further, that if a claim is settled by the Indemnitee with the Company’s written consent, or if
there be a final judgment or decree for the plaintiff in connection with the Claim by a court of competent jurisdiction, the Company shall indemnify and hold harmless Indemnitee from and against any and all losses, costs, expenses and liabilities
incurred by reason of such settlement or judgment. 
  
 (c)    Indemnitee shall give the Company such information and cooperation as it may reasonably require and as shall be within Indemnitee’s power. 
  
 (d)    Any indemnification provided for in Section 1 shall be made no later than
forty-five (45) days after receipt of the written request of Indemnitee. If a Claim under this Agreement, under any statute, or under any provision of the Company’s Certificate of Incorporation or Bylaws providing for indemnification, is not
paid in full by the Company within forty-five (45) days, or any advance of expenses pursuant to Section 4 is not paid in full by the Company within twenty (20) days, after a written request for payment thereof has first been received by the Company,
Indemnitee may, but need not, at any time thereafter bring an action against the Company to recover the unpaid amount of the claim and, subject to Section 13 of this Agreement, Indemnitee shall also be entitled to be reimbursed for the expenses
(including attorneys’ fees) of bringing such action. It shall be a defense to any such action (other than an action brought to enforce a claim for expenses incurred in connection with any action or proceeding in advance of its final
disposition) that Indemnitee has not met the standards of conduct which make it permissible under applicable law for the Company to indemnify Indemnitee for the amount claimed but the burden of proving such defense shall be on the Company, and
Indemnitee shall be entitled to receive interim payments of expenses pursuant to Subsection 4 unless and until such defense may be finally adjudicated by court order or judgment from which no further right of appeal exists. It is the parties’
intention that if the Company contests Indemnitee’s right to indemnification, the question of Indemnitee’s right to indemnification shall be for the court to decide, and neither the failure of the Company (including its Board of Directors,
any committee or subgroup of the Board of Directors, independent legal counsel, or its stockholders) to have made a determination that indemnification of Indemnitee is proper in the circumstances because Indemnitee has met the applicable standard of
conduct required by applicable law, nor an actual determination by the Company (including its Board of Directors, any committee or subgroup of the Board of Directors, independent legal counsel, or its stockholders) that Indemnitee has not met such
applicable standard of conduct, shall create a presumption that Indemnitee has or has not met the applicable standard of conduct. 
  
 (e)    If, at the time of the receipt of a notice of a Claim, the Company has director and officer liability insurance
in effect, the Company shall give prompt notice of the commencement of such proceeding to the insurers in accordance with the procedures set forth in the respective policies. The Company shall thereafter take all necessary or desirable action to
cause such insurers to pay, on behalf of the Indemnitee, all amounts payable as a result of such proceeding in accordance with the terms of such policies. 
  

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 6.    Scope.    Notwithstanding any other provision of
this Agreement, the Company hereby agrees to indemnify the Indemnitee against any Claim to the fullest extent permitted by law, notwithstanding that such indemnification is not specifically authorized by the other provisions of this Agreement, the
Company’s Certificate of Incorporation, the Company’s Bylaws or by statute. In the event of any change, after the date of this Agreement, in any applicable law, statute or rule which expands the right of a Delaware corporation to indemnify
a member of its board of directors, an officer or other corporate agent, such changes shall be, ipso facto, within the purview of Indemnitee’s rights and Company’s obligations, under this Agreement. In the event of any change in any
applicable law, statute, or rule which narrows the right of a Delaware corporation to indemnify a member of its Board of Directors, an officer, or other corporate agent, such changes, to the extent not otherwise required by applicable law to be
applied to this Agreement, shall have no effect on this Agreement or the parties’ rights and obligations hereunder. 
  
 7.    Partial Indemnification.    If Indemnitee is entitled under any provision of this Agreement to
indemnification by the Company for some or a portion of the expenses, judgments, fines or penalties actually or reasonably incurred by him in the investigation, defense, appeal or settlement of any civil or criminal action or proceeding, but not,
however, for the total amount thereof, the Company shall nevertheless indemnify Indemnitee for the portion of such expenses, judgments, fines or penalties to which Indemnitee is entitled. 
  
 8.    Public Policy.    Both the Company and Indemnitee acknowledge that in
certain instances, Federal law or applicable public policy may prohibit the Company from indemnifying its directors and officers under this Agreement or otherwise. Indemnitee understands and acknowledges that the Company has undertaken or may be
required in the future to undertake with the Securities and Exchange Commission to submit the question of indemnification to a court in certain circumstances for a determination of the Company’s right under public policy to indemnify
Indemnitee. 
  
 9.    Insurance.    Although the Company may from time to time maintain insurance for the purpose of indemnifying Indemnitee and other agents of the Company against personal liability,
including costs of legal defense, nothing in this Agreement shall obligate the Company to do so. 
  
 10.    No Restrictions.    The rights and remedies of Indemnitee under this Agreement shall not be deemed
to exclude or impair any other rights or remedies to which Indemnitee may be entitled under the Certificate of Incorporation or Bylaws of the Company, or under any other agreement, provision of law or otherwise, nor shall anything contained herein
restrict the right of the Company to indemnify Indemnitee in any proper case even though not specifically provided for in this Agreement, nor shall anything contained herein restrict Indemnitee’s right to contribution as may be available under
applicable law. 
  
 11.    Termination.    The Company may terminate this Agreement at any time upon 90 days written notice, but any such termination will not affect Claims relating to events occurring prior to
the effective date of termination. 
  
 12.    Severability.    Each of the provisions of this Agreement is a separate and distinct agreement and independent of the others, so that if any provision hereof shall be held to be invalid
or 

  

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unenforceable for any reason, such invalidity or unenforceability shall not affect the validity or enforceability of the other provisions hereof. 

 
 13.    Attorneys’
Fees.    In the event of any litigation or other action or proceeding to enforce or interpret this Agreement, the prevailing party as determined by the court shall be entitled to an award of its reasonable attorneys’
fees and other costs, in addition to such relief as may be awarded by a court or other tribunal. 
  
 14.    Further Assurances.    The parties will do, execute and deliver, or will cause to be done, executed
and delivered, all such further acts, documents and things as may be reasonably required for the purpose of giving effect to this Agreement and the transactions contemplated hereby. 
  
 15.    Acknowledgment.    The Company expressly acknowledges that it has
entered into this Agreement and assumed the obligations imposed on the Company hereunder in order to induce Indemnitee to serve or to continue to serve as an agent of the Company, and acknowledges that Indemnitee is relying on this Agreement in
serving or continuing to serve in such capacity. 
  
 16.    Construction of Certain Phrases. 
  
 (a)    “Company”:    For purposes of this Agreement, references to the “Company” shall also include, in addition to the resulting corporation in any
consolidation or merger to which the Company is a party, any constituent corporation (including any constituent of a constituent) absorbed in consolidation or merger which, if its separate existence had continued, would have had power and authority
to indemnify its directors, officers, employees or agents, so that if Indemnitee is or was a director, officer, employee or agent of such constituent corporation, or is or was serving at the request of such constituent corporation as a director,
officer, employee or agent of another corporation, partnership, joint venture, trust or other enterprise, Indemnitee shall stand in the same position under the provisions of this Agreement with respect to the resulting or surviving corporation as
Indemnitee would have with respect to such constituent corporation if its separate existence had continued. 
  
 (b)    Benefit Plans:    References to “fines” contained in this Agreement shall
include any excise taxes assessed on Indemnitee with respect to an employee benefit plan; and references to “serving at the request of the Company” shall include any service as a director, officer, employee or agent of the Company which
imposes duties on, or involves services by, such director, officer, employee or agent with respect to an employee benefit plan, its participants, or beneficiaries. 
  
 17.    Counterparts.    This Agreement may be executed in one or more
counterparts, each of which shall constitute an original. 
  
 18.    Notice.    All notices, requests, demands and other communications under this Agreement shall be in writing and shall be deemed duly given (i) if delivered by hand and receipted for by
the party addressee, on the date of such receipt, or (ii) if mailed by domestic certified or registered mail with postage prepaid, on the third business day after the date postmarked. Addresses for notice to either party are as shown on the
signature page of this Agreement, or as subsequently modified by written notice. 
  

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 19.    Governing Law; Binding Effect; Amendment. 
  
 (a)    This Agreement shall be
interpreted and enforced in accordance with the laws of the State of Delaware applicable to contracts entered into in Delaware. 
  
 (b)    This Agreement shall be binding upon Indemnitee and the Company, their successors and assigns, and shall inure
to the benefit of Indemnitee, his heirs, personal representatives and assigns and to the benefit of the Company, its successors and assigns. 
  
 (c)    No amendment, modification, termination or cancellation of this Agreement shall be effective unless in writing
signed by both parties hereto. 
  
 IN WITNESS WHEREOF, the
parties hereto have executed this Agreement as of the date first above written. 
  

	TERCICA MEDICA, INC.
	
	By:
                                        
                                        
               
	
	Its:
                                        
                                        
                
	
	Address:
                                        
                                        
     
	
	              
                                        
                                        
     

  

	INDEMNITEE
	
	Signature:
                                        
                                        
  
	
	Name:
                                        
                                        
         
	
	Address:
                                        
                                        
     
	
	              
                                        
                                        
     

  

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