Document:

Fourth Amended and Restated Voting Agreement

 Exhibit 10.10 
 SAGENT HOLDING CO. 
 FOURTH AMENDED AND RESTATED VOTING AGREEMENT

 This Fourth Amended and Restated Voting Agreement (this “Agreement”) is made and entered into as of
September 3, 2010, by and among Sagent Holding Co., a Cayman Islands exempted company (the “Company”), each of the members listed on Exhibit A attached hereto (collectively, the “Existing Investors”),
each of the members listed on Exhibit B attached hereto (collectively, the “Key Ordinary Shareholders”), and each of the members listed on Exhibit C attached hereto (the “New Investors”, and together
with the Existing Investors, the “Investors”). The Investors and Key Ordinary Shareholders are sometimes collectively referred to herein as the “Members.” 

RECITALS 

A. The Company is issuing to the New Investors additional Series B-1 Preference Shares of the Company (“Series B-1
Shares”) pursuant to the Series B-1 Preference Shares Purchase Agreement dated as of September 3, 2010 (as may be amended from time to time, the “B-1 Extension Purchase Agreement”). 

B. The Company, the Key Ordinary Shareholders and the Existing Investors are parties to that certain Third Amended and Restated Voting
Agreement dated as of April 6, 2010 (the “Prior Agreement”). 
 C. The Company’s Sixth Amended and
Restated Articles of Association (as may be amended from time to time, the “Amended Articles”) provide that, subject to certain shareholding requirements, (i) the holders of a majority of the outstanding Ordinary Shares of the
Company (“Ordinary Shares”) shall be entitled to elected one (1) director of the Company (the “Ordinary Share Director”), (ii) the holders of a majority of outstanding Series A Preference Shares of the
Company (the “Series A Shares”) shall be entitled to elect four (4) directors of the Company (the “Series A Directors”), (iii) the holders of a majority of the outstanding Series B-1 Shares shall be
entitled to elect one (1) director of the Company (the “Series B-1 Director”) and (iv) the holders of a majority of outstanding Ordinary Shares and Series A Shares, Series B Preference Shares and Series B-1 Shares
(collectively, the “Preference Shares”), voting together as a single class on an as-converted basis, shall be entitled to elect one (1) director of the Company (the “Independent Director”). 

D. It is a condition to the closing of the sale of additional Series B-1 Shares to the New Investors pursuant to the B-1 Extension
Purchase Agreement that the parties to the Prior Agreement to enter into this Agreement and amend and restate the Prior Agreement. 
 E. The undersigned parties and the Company (each a “Party” and collectively, the “Parties”) desire to amend and restate in its entirety the Prior Agreement as set forth
herein and to accept the rights and obligations created pursuant hereto in lieu of their rights and obligations under the Prior Agreement. 

  
 1 

 F. In connection with the closing of the sale of Series B-1 Shares pursuant to the B-1
Extension Purchase Agreement, the parties hereto have agreed to provide for the future voting of their shares of the Company’s capital stock as set forth below. 
 AGREEMENT 
 NOW, THEREFORE, in consideration of the foregoing premises and
certain other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the Parties hereto agree as follows: 
 1. Definitions. As used herein, the following terms shall have the following meanings: 
 (a) “Board” means the board of directors of the Company. 
 (b)
“Board Designee” means any individual who is designated for election to the Board pursuant to Section 4 of this Agreement. 
 (c) “Deemed Liquidation Event” has the meaning set forth in the Amended Articles, as may be amended from time to time. 

(d) “Designator” means any person, entity or group of persons or entities who, at the time in question, have the right
to designate any Board Designee. 
 (e) “Recapitalization” means any share split, share dividend, share
combination or consolidation, recapitalization, reclassification or other similar event in relation to shares of the Company. 

2. Agreement to Vote. The Members each hereby agree to hold all voting shares of the Company, including, but not limited to, any
Preference Shares and Ordinary Shares registered in their respective names or beneficially owned by them as of the date hereof and any and all other securities of the Company legally or beneficially acquired by them after the date hereof (the
“Shares”) subject to, and to vote such Shares in accordance with, the provisions of this Agreement. Upon the failure of any Member to vote its Shares in accordance with the terms of this Agreement, such Member hereby grants to a
member designated by the Board a proxy coupled with an interest in all Shares owned by such Member, which proxy shall be irrevocable until this Agreement terminates pursuant to its terms or this Section 2 is amended to remove such grant of
proxy in accordance with Section 14 hereof, to vote all such Shares in the matter provided in Sections 3, 4, and 5 hereof. 

3. Size of the Board. During the term of this Agreement, the Members agree to vote all Shares to maintain the authorized number of
members of the Board as set forth in the Amended Articles unless otherwise agreed to in writing by the members of the Company in accordance with the Amended Articles. 
 4. Designation of Directors. Each of the Members shall vote at any regular or special meeting of members such number of Shares as may be necessary, or in lieu of any such meeting, shall give such
Member’s written consent with respect to such number of Shares as may be necessary, to elect: 

  
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 (a) as the one (1) Ordinary Share Director, the Board Designee nominated by the holders
of a majority of outstanding Ordinary Shares, which initial Board Designee shall be Jeffrey Yordon; 
 (b) as the four
(4) Series A Directors, each of the following: 
 (i) the Board Designee nominated by Vivo Ventures Fund
Cayman V, L.P., so long as Vivo Ventures Fund Cayman V, L.P. (together with its affiliates) holds at least 3,000,000 Series A Shares (as adjusted for any share split, dividend or combination with respect to the Series A Shares), which Board Designee
shall initially be Chen Yu; 
 (ii) the Board Designee nominated by Vivo Ventures Fund Cayman VI, L.P., so long
as Vivo Ventures Fund Cayman VI, L.P. (together with its affiliates) holds at least 3,000,000 Series A Shares (as adjusted for any share split, dividend or combination with respect to the Series A Shares), which Board Designee shall initially be
Frank Kung; and 
 (iii) the Board Designee nominated by Morgan Stanley Investment Management Inc., so long as
certain investment portfolios and separate accounts managed by Morgan Stanley Investment Management Inc. and its affiliates hold at least 3,000,000 Series A Shares (as adjusted for any share split, dividend or combination with respect to the Series
A Shares), which Board Designee shall initially be James Sperans; and 
 (iv) the Board Designee nominated by CNF
Investments II, LLC, so long as CNF Investments II, LLC (together with its affiliates) holds at least 3,000,000 Series A Shares (as adjusted for any share split, dividend or combination with respect to the Series A Shares), which Board Designee
shall initially be Robert Flanagan; and 
 (c) as the one (1) Series B-1 Director, the Board Designee nominated by Key Gate
Investments Limited, a British Virgin Islands company, so long as Key Gate Investments Limited and its affiliates hold at least 3,000,000 Series B-1 Shares (as adjusted for any share split, dividend or combination with respect to the Series B-1
Shares), which Board Designee shall initially be Mark Qiu; and 
 (d) as the one (1) Independent Director, the Board
Designee, who shall be an independent industry representative, nominated by the holders of a majority of outstanding Ordinary Shares and outstanding Preference Shares, voting together as a single class on an as-converted basis. 

  
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 5. Removal and Filling of Vacancies. From time to time during the term of this
Agreement, the Designator may, in its sole discretion: 
 (a) elect to remove from the Board any incumbent Board Designee who
occupies a Board seat for which such Designator then is entitled to designate the Board Designee under Section 4 above; and/or 
 (b) designate a new Board Designee for election to a Board seat for which such Designator is then entitled to designate the Board Designee under Section 4, above (whether to replace a prior Board
Designee or to fill a vacancy in such Board seat). 
 In the event of such removal and/or designation, each Member agrees to
vote its Shares as necessary under Section 4 above to cause the removal from the Board of any Board Designee so designated for removal by the appropriate Designator and the election to the Board of any new Board Designee so designated for
election to the Board by the then appropriate Designator. 
 6. Legend on Share Certificates. Each certificate
representing any Shares held by the Members shall be endorsed by the Company with a legend in substantially the following form: 

“THE SHARES REPRESENTED BY THIS CERTIFICATE ARE SUBJECT TO A VOTING AGREEMENT ENTERED INTO BY THE HOLDER OF THESE SHARES, THE COMPANY
AND CERTAIN MEMBERS OF THE COMPANY. A COPY OF SUCH AGREEMENT IS ON FILE AT THE PRINCIPAL OFFICE OF THE COMPANY. BY ACCEPTING ANY INTEREST IN SUCH SHARES THE PERSON ACCEPTING SUCH INTEREST SHALL BE DEEMED TO AGREE TO AND SHALL BECOME BOUND BY ALL THE
PROVISIONS OF SAID VOTING AGREEMENT.” 
 7. Binding Effect. The provisions of this Agreement shall be binding upon
the successors in interest to any of the Shares. The Company shall not permit the transfer of any of the Shares on its books or issue a new certificate representing any of the Shares unless and until the person to whom such security is to be
transferred shall have executed a written agreement, substantially in the form of this Agreement or a joinder agreement approved by the Company, pursuant to which such person becomes a party to this Agreement and agrees to be bound by all the
provisions hereof as if such person were an Investor or Key Ordinary Shareholder, as applicable. Any party who executes a joinder agreement with the Company in respect of this Agreement shall, for all purposes, be deemed an
“Investor” or a “Key Ordinary Shareholder” hereunder, as applicable. 
 8. Execution by the
Company. The Company, by its execution in the space provided below, agrees that it will cause the certificates evidencing the Shares to bear the legend required by Section 6 herein, and it shall supply, free of charge, a copy of this
Agreement to any holder of a certificate evidencing Shares containing such legend upon written request from such holder to the Company at its principal office. The Parties do hereby agree that the failure to cause the certificates evidencing the
appropriate Shares to bear the legend required by Section 6 herein and/or failure of the Company to supply, free of charge, a copy of this Agreement as provided under this Section 8 shall not affect the validity or enforcement of this
Agreement. 

  
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 9. Specific Enforcement. Except as otherwise provided herein, any and all remedies
expressly conferred upon a Party by this Agreement will be deemed cumulative with and not exclusive of any other remedy conferred hereby, or by law or equity upon such Party, and the exercise by a Party of any one remedy will not preclude the
exercise of any other remedy. The Parties agree that irreparable damage would occur in the event that any of the provisions of this Agreement were not performed in accordance with their specific terms or were otherwise breached. It is accordingly
agreed that the Parties shall be entitled to seek an injunction or injunctions to prevent breaches of this Agreement and to enforce specifically the terms and provisions hereof in any federal or state court in the State of California, this being in
addition to any other remedy to which they are entitled at law or in equity. 
 10. Captions. The captions, headings and
arrangements used in this Agreement are for convenience only and do not in any way limit or amplify the terms and provisions hereof. 
 11. Notices. All notices and other communications required or permitted hereunder shall be in writing and shall be mailed by electronic, registered or certified mail or by overnight courier or
otherwise delivered by hand or by messenger, addressed: 
 (a) if to an Investor, at the Investor’s address as shown on
Exhibit A or Exhibit C attached hereto, or at such other address as the Investors shall have furnished to the Company in writing; 
 (b) if to a Key Ordinary Shareholder, at the Key Ordinary Shareholder’s address as shown on Exhibit B attached hereto, or at such other address as the Key Ordinary Shareholders shall have
furnished to the Company in writing; 
 (c) if to any other holder of any Shares subject to this Agreement, at such address as
such holder shall have furnished the Company in writing, or, until any such holder so furnishes an address to the Company, then to and at the address of the last holder of such Shares who has so furnished an address to the Company; and 

(d) if to the Company, at the address of its principal corporate offices (attention: Chief Executive Officer), or at such other address
as the Company shall have furnished to the Members, 
 with a copy to: 

Carmen Chang 

Wilson Sonsini Goodrich & Rosati, P.C. 
 650 Page Mill Road 
 Palo Alto, CA 94304 

Facsimile: (650) 493-6811 
 Email: cchang@wsgr.com 

  
 5 

 Where a notice is sent by mail, service of the notice shall be effected by properly
addressing, pre-paying and mailing a letter containing the notice, and to have been effected at the expiration of three (3) business days after the letter containing the same is mailed as aforesaid. 

Where a notice is sent by overnight courier, service of the notice shall be effected by properly addressing, and sending such notice
through an internationally recognized express courier service, delivery fees pre-paid, and to have been effected three (3) business days following the day the same is sent as aforesaid. 

Where a notice is delivered by electronic mail, by hand or by messenger, service of the notice shall be deemed to be effected upon
delivery. 
 12. Term. This Agreement shall terminate and be of no further force or effect upon the earlier to occur of:
(a) the effectiveness of the registration statement for the Company’s first firm commitment underwritten public offering registered under the Securities Act of 1933, as amended, or pursuant to the securities laws applicable to an offering
of securities in another jurisdiction pursuant to which such securities will be listed on an internationally-recognized securities exchange; (b) the effectiveness of a Deemed Liquidation Event; (c) any time when less than 5,000,000 Series
A Shares remain outstanding and less than 5,000,000 Series B-1 Shares remain outstanding. 
 13. Manner of Voting. The
voting of shares pursuant to this Voting Agreement may be effected in person, by proxy, by written consent, or in any other manner permitted by applicable law. 
 14. Amendments and Waivers. Any term hereof may be amended and the observance of any term hereof may be waived (either generally or in a particular instance and either retroactively or
prospectively) only with the written consent of (a) the Company, (b) the Investors holding a majority in interest of the then outstanding Preference Shares, (c) a majority-in-interest of the Key Ordinary Shareholders, (d) the
Investors holding a majority in interest of the then outstanding Series A Shares and (e) the Investors holding a majority in interest of the then outstanding Series B-1 Shares. All such amendments shall be binding on all parties hereto.

 15. Share Splits, Share Dividends, etc. In the event of any Recapitalization, such shares or securities shall be
deemed to be Shares for purposes of this Agreement and shall be endorsed with the legend set forth above. 
 16.
Severability. Whenever possible, each provision of this Agreement shall be interpreted in such manner as to be effective and valid under applicable law, but if any provision of this Agreement shall be held to be prohibited by or invalid under
applicable law, such provision shall be ineffective only to the extent of such prohibition or invalidity, without invalidating the remainder of such provision or the remaining provisions of this Agreement. 

17. Successors. This Agreement shall inure to the benefit of and be binding upon the Parties and their respective heirs,
successors, assigns, administrators, executors and other legal representatives. 

  
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 18. Governing Law. This Agreement shall be governed by, and construed and enforced in
accordance with, the internal laws of the State of California as such laws are applied to agreements between California residents entered into and to be performed within California. Each of the Parties irrevocably: (a) agrees that any dispute
or controversy arising out of, relating to, or concerning any interpretation, construction, performance or breach of this Agreement, shall be settled by arbitration to be held in Santa Clara County, California, in accordance with the rules then in
effect of the American Arbitration Association; (b) waives, to the fullest extent it may effectively do so, any objection which it may now or hereafter have to the laying of venue of any such arbitration; and (c) submits to the exclusive
jurisdiction of the State of California in any such arbitration. The Parties hereby acknowledge and agree that (a) any decision of the arbitrator shall be final, conclusive and binding on the parties to the arbitration; (b) judgment may be
entered on the arbitrator’s decision in any court having jurisdiction; and the parties to the arbitration shall each pay an equal share of the costs and expenses of such arbitration, and each such party shall separately pay for its respective
counsel fees and expenses; provided, however, that the prevailing party in any such arbitration shall be entitled to recover from the non-prevailing party its reasonable costs and attorney fees. 

19. Entire Agreement. This Agreement, along with the B-1 Extension Purchase Agreement and each of the exhibits thereto,
constitutes the full and entire understanding and agreement between the Parties with respect to the subject hereof and thereof and supersedes, merges, and renders void any and all prior understandings and/or agreements, written or oral, with respect
to such subject matter. 
 20. Counterparts; Facsimiles. This Agreement may be executed in two or more counterparts, each
of which shall be deemed an original, but all of which together shall constitute one and the same instrument. A facsimile, telecopy or other reproduction of this Agreement may be executed by one or more Parties and delivered by such Party by
facsimile or any similar electronic transmission device pursuant to which the signature of or on behalf of such Party can be seen. Such execution and delivery shall be considered valid, binding and effective for all purposes. At the request of any
Party, all Parties severally agree to execute and deliver an original of this Agreement as well as any facsimile, telecopy or other reproduction hereof. 
 21. Amendment and Restatement. The Prior Agreement is hereby superseded and amended in its entirety and restated in this Agreement. All provisions of, rights granted and covenants made in the
Prior Agreement are hereby terminated, waived, released and superseded in their entirety and shall have no further force or effect. 
 22. New Investors. Notwithstanding anything herein to the contrary, if pursuant to an agreement (including the B-1 Extension Purchase Agreement, as may be amended time to time), additional parties
may purchase Series B-1 Shares as “Purchasers” thereunder, then each such Purchaser shall become a Party to this Agreement as an “Investor” hereunder, without the need for any consent, approval or signature of any
Investor when such Purchaser has both (i) purchased Series B-1 Shares under such agreement, and paid the Company all consideration payable for such shares and (ii) executed a copy of this Agreement as an “Investor.”

 [REMAINDER OF PAGE INTENTIONALLY LEFT BLANK] 

  
 7 

 IN WITNESS WHEREOF, the Parties hereto have executed this Agreement as of the date first
above written. 
  

			
	COMPANY:
	
	SAGENT HOLDING CO.,
	a Cayman Islands exempted company
	
	By: /s/ Jeffrey
Yordon                                        
        
	Name:	 	Jeffrey Yordon
	Title:	 	President and Chief Executive Officer

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED VOTING AGREEMENT 

 IN WITNESS WHEREOF, the Parties hereto have executed this Agreement as of the date first
above written. 
  

	
	KEY ORDINARY SHAREHOLDERS:
	
	JEFFREY YORDON
	
	By: /s/ Jeffrey
Yordon                                        
        
	(signature)
	
	LORIN DRAKE
	
	By: /s/ Lorin
Drake                                        
            
	(signature)
	
	ANTHONY GULCZYNSKI
	
	By: /s/ Anthony
Gulczynski                                        

	(signature)

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED VOTING AGREEMENT 

 IN WITNESS WHEREOF, the Parties hereto have executed this Agreement as of the date first
above written. 
  

	
	KEY ORDINARY SHAREHOLDERS:
	
	VIVO VENTURES FUND CAYMAN V, L.P.
	
	By: Vivo Ventures Cayman V (GP), L.P.
	
	By: Vivo Ventures Cayman V General Partner Limited, its general partner
	
	By: /s/ Frank
Kung                                         
           
	(signature)
	
	Name: Frank Kung
	Title: Director
	
	VIVO VENTURES V AFFILIATES FUND, L.P.
	
	By: /s/ Frank
Kung                                         
           
	(signature)
	
	Name: Frank Kung
	 Title: Managing Member of Vivo Ventures V, LLC,
 its General Partner

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED VOTING AGREEMENT 

 IN WITNESS WHEREOF, the Parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	VIVO VENTURES FUND CAYMAN V, L.P.
	
	By: Vivo Ventures Cayman V (GP), L.P.
	
	By: Vivo Ventures Cayman V General Partner Limited, its general partner
	
	By: /s/ Frank
Kung                                         
           
	(signature)
	
	Name: Frank Kung
	Title: Director
	
	VIVO VENTURES V AFFILIATES FUND, L.P.
	
	By: /s/ Frank
Kung                                         
           
	(signature)
	
	Name: Frank Kung
	 Title: Managing Member of Vivo Ventures V, LLC,
 its General Partner

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED VOTING AGREEMENT 

 IN WITNESS WHEREOF, the Parties hereto have executed this Agreement as of the date first
above written. 
  

			
	INVESTORS:
	
	PACIFIC SEQUOIA HOLDINGS LLC
	
	By: /s/ John V.
Jonson                                        
        
	Name:	 	John V. Jonson
	Title:	 	Manager

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED VOTING AGREEMENT 

 IN WITNESS WHEREOF, the Parties hereto have executed this Agreement as of the date first
above written. 
  

			
	 INVESTORS:

	
	 THE SKOLL FOUNDATION

	
	By: /s/ John V.
Jonson                                        
        
	Name:	 	John V. Jonson
	Title:	 	Manager

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED VOTING AGREEMENT 

 IN WITNESS WHEREOF, the Parties hereto have executed this Agreement as of the date first
above written. 
  

			
	INVESTORS:
	
	THE SKOLL FUND
	
	By: /s/ John V.
Jonson                                        
        
	Name:	 	John V. Jonson
	Title:	 	Manager

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED VOTING AGREEMENT 

 IN WITNESS WHEREOF, the Parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	 WEYERHAEUSER COMPANY MASTER
 RETIREMENT TRUST

	 Managed by Morgan Stanley Investment
 Management, Inc.

	
	 By: The Bank of New York Mellon, not individually
 but solely in its capacity as Directed Trustee on
 behalf of the Trust

	
	By: /s/ Bernadette T.
Rist                                         
   
	Name: Bernadette T. Rist
	Authorized Signatory

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED VOTING AGREEMENT 

 IN WITNESS WHEREOF, the Parties hereto have executed this Agreement as of the date first
above written. 
  

			
	INVESTORS:
	
	 SAILORSHELL & CO. FOR THE BENEFIT
 OF MORGAN STANLEY AIP GLOBAL
 DIVERSIFIED FUND LP

		
	By:	 	Morgan Stanley Alternative Investment Partners LP, its general partner
	By:	 	Morgan Stanley AIP GP LP, its general partner
	By:	 	Morgan Stanley Alternative Investments Inc., its general partner

 

			
	By: /s/ James
Sperans                                        
          
	Name:	 	James Sperans
	Title:	 	Managing Director

  

			
	 SAILORPIER & CO. FOR THE BENEFIT OF
 AURORA CAYMAN LIMITED

		
	By:	 	Morgan Stanley Investment Management Inc., its investment manager

 

			
	By: /s/ James
Sperans                                        
          
	Name:	 	James Sperans
	Title:	 	Managing Director

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED VOTING AGREEMENT 

 IN WITNESS WHEREOF, the Parties hereto have executed this Agreement as of the date first
above written. 
  

			
	INVESTORS:
	
	STORMBAY & CO. FOR THE BENEFIT OF VIJVERPOORT HUIZEN C.V.
		
	By:	 	Morgan Stanley Alternative Investment Partners LP, its general partner
	By:	 	Morgan Stanley AIP GP LP, its general partner
	By:	 	Morgan Stanley Alternative Investments Inc., its general partner

 

			
	By: /s/ James
Sperans                                        
          
	Name:	 	James Sperans
	Title:	 	Managing Director

  

			
	STORMLAUNCH & CO. FOR THE BENEFIT OF MORGAN STANLEY PRIVATE MARKETS FUND III LP
		
	By:	 	Morgan Stanley Alternative Investment Partners LP, its general partner
	By:	 	Morgan Stanley AIP GP LP, its general partner
	By:	 	Morgan Stanley Alternative Investments Inc., its general partner

 

			
	By: /s/ James
Sperans                                        
          
	Name:	 	James Sperans
	Title:	 	Managing Director

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED VOTING AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

			
	INVESTORS:
	
	STORMSTAR & CO. FOR THE BENEFIT OF MORGAN STANLEY PRIVATE MARKETS FUND EMPLOYEE INVESTORS III LP
		
	By:	 	Morgan Stanley Alternative Investment Partners LP, its general partner
	By:	 	Morgan Stanley AIP GP LP, its general partner
	By:	 	Morgan Stanley Alternative Investments Inc., its general partner

 

			
	By: /s/ James
Sperans                                        
          
	Name:	 	James Sperans
	Title:	 	Managing Director

  

			
	NUCLEAR ELECTRIC INSURANCE LIMITED
	
	By: Morgan Stanley Investment Management Inc., its investment manager
	
	By: /s/ James
Sperans                                        
          
	(signature)	 	
	Name: James Sperans
	Title: Executive Director

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED VOTING AGREEMENT 

 IN WITNESS WHEREOF, the Parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	FACTORY MUTUAL INSURANCE COMPANY
	
	By: /s/ Paul
LaFleche                                        
          
	Name: Paul LaFleche
	Title:   Senior Vice President of Investments

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED VOTING AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	CNF INVESTMENTS II, LLC
	
	 By:    /s/ Robert J.
Flanagan                                

	 (signature)

	
	 Name: Robert J. Flanagan

	 Title: Manager

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED VOTING AGREEMENT 

 IN WITNESS WHEREOF, the Parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	VIVO VENTURES VI AFFILIATES FUND L.P.
	By: Vivo Ventures VI, LLC, its Managing Member
	
	By: /s/ Frank
Kung                                         
             
	(signature)
	
	Name: Frank Kung
	Title: General Partner
	
	VIVO VENTURES FUND CAYMAN VI, L.P.
	By: Vivo Venture Cayman VI (GP), L.P.
	 By: Vivo Ventures Cayman VI General Partner
        Limited, its general partner

	
	By: /s/ Frank
Kung                                         
             
	(signature)
	
	Name: Frank Kung
	Title: Director

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED VOTING AGREEMENT 

 IN WITNESS WHEREOF, the Parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	KEY GATE INVESTMENTS LIMITED
	
	By: /s/ Andrew
Lo                                         
               
	(signature)
	
	Name: Andrew Lo
	Title: Authorized Representative

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED VOTING AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	LINK BEST CAPITAL LIMITED
	
	By: /s/ Shing Chi
Yap                                         
         
	(signature)
	
	Name: Shing Chi Yap
	Title: Director

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED VOTING AGREEMENT 

 IN WITNESS WHEREOF, the parties hereto have executed this Agreement as of the date first
above written. 
  

	
	INVESTORS:
	
	WESTFIELD CAPITAL MANAGEMENT
	
	 By: Westfield Partners, L.L.C., its General Partner
 By: Westfield Capital Management Company, L.P.,
 it’s Manager

By: WMS General Partner, LLC, its General Partner

	
	By: /s/ William A.
Muggia                                        
  
	 William A. Muggia, an Authorized Person

  

SIGNATURE PAGE TO SAGENT HOLDING CO.
FOURTH AMENDED AND RESTATED VOTING AGREEMENT 

 Exhibit A 

Existing Investors 

Vivo Ventures Fund Cayman VI, L.P. 
 575
High Street, Suite 201 
 Palo Alto, CA 94301 
 Attn: Chen Yu 
 Vivo Ventures Fund Cayman V, L.P. 

c/o Vivo Ventures V, LLC 
 575 High Street, Suite
201 
 Palo Alto, CA 94301 
 Attn: Chen
Yu 
 Vivo Ventures VI Affiliates Fund, L.P. 
 575 High Street, Suite 201 
 Palo Alto, CA 94301 

Attn: Chen Yu 
 Vivo Ventures V Affiliates
Fund, L.P. 
 c/o Vivo Ventures V, LLC 
 575 High Street, Suite 201 
 Palo Alto, CA 94301 

Attn: Chen Yu 
 Stormlaunch & Co.
for the Benefit of Morgan Stanley Private Markets Fund III LP 
 c/o Morgan Stanley Alternative Investments Inc. 

100 Front Street, Suite 400 
 West Conshohocken,
Pennsylvania 19428-2881 
 Attn: Matthew Allen, Executive Director 
 Stormstar & Co. for the Benefit of Morgan Stanley Private Markets Fund Employee Investors III LP 
 c/o Morgan Stanley Alternative Investments Inc. 
 100 Front Street, Suite 400 

West Conshohocken, Pennsylvania 19428-2881 

Attn: Matthew Allen, Executive Director 
 CNF
Investments II, LLC 
 7500 Old Georgetown Road 
 Bethesda, MD 20814 
 Attn: Robert Flanagan 

Weyerhaeuser Company Master Retirement Trust 
 c/o The Bank of New York Mellon 
 Legal Department 

500 Grant Street 
 BNY Mellon Center 

AIM: 151-1935 
 Pittsburgh, Pennsylvania
15258-0001 
 Attn: Bernadette Rist 

 Sailorshell & Co. for the benefit of Morgan Stanley AIP Global Diversified Fund LP

 c/o Morgan Stanley Alternative Investments Inc. 
 100 Front Street, Suite 400 
 West Conshohocken, Pennsylvania 19428-2881 

Attn: Matthew Allen, Executive Director 

Dohmen Investment Group, LLC  

215 North Water Street  

Milwaukee, WI 53202 
 Attn: John Vaughan, Chief
Financial Officer 
 Pacific Sequoia Holdings LLC 
   c/o Capricorn Management, LLC 
   250 University Avenue, Suite 300

   Palo Alto, CA 94301 

  Attn: John Johnson 
   c/o
Mellon Global Securities Services 
   135 Santilli Highway 
   026-0035 
   Everett, MA 02149 

  Attn: Nicole Strazzulla 

  c/o Seiler & Company 

  1100 Marshall Street 

  Redwood City, CA 94063 

  Attn: James G. B. DeMartini III, CPA 

Stormbay & Co. for the benefit of Vijverpoort Huizen C.V. 
 c/o Morgan Stanley Alternative Investments Inc. 
 100 Front Street, Suite 400 

West Conshohocken, Pennsylvania 19428-2881 

Attn: Matthew Allen, Executive Director 

Sailorpier & Co. for the benefit of Aurora Cayman Limited 
 c/o Morgan Stanley Alternative Investments Inc. 
 100 Front Street, Suite 400 

West Conshohocken, Pennsylvania 19428-2881 

Attn: Matthew Allen, Executive Director 
 The
Skoll Foundation 
   c/o Capricorn Management, LLC 
   250 University Avenue, Suite 300 
   Palo Alto, CA 94301 

  Attn: John Johnson 
   c/o
Mellon Global Securities Services 
   135 Santilli Highway 
   026-0035 
   Everett, MA 02149 

  Attn: Nicole Strazzulla 

  c/o Seiler & Company 

  1100 Marshall Street 

  Redwood City, CA 94063 

  Attn: James G. B. DeMartini III, CPA 

 The Skoll Fund 
   c/o Capricorn Management, LLC 
   250 University Avenue, Suite 300

   Palo Alto, CA 94301 

  Attn: John Johnson 
   c/o
Mellon Global Securities Services 
   135 Santilli Highway 
   026-0035 
   Everett, MA 02149 

  Attn: Nicole Strazzulla 

  c/o Seiler & Company 

  1100 Marshall Street 

  Redwood City, CA 94063 

  Attn: James G. B. DeMartini III, CPA 

Factory Mutual Insurance Company 
 225
Wyman Street 
 Waltham, MA 02454 

Attn: Paul LaFleche, Senior Vice President of Investments 
 Nuclear Electric Insurance Limited 
 1201 North Market Street, 11th Floor 

Wilmington, DE 19801 
 Attn: Robert MacGovern,
Vice President - Investments 
 CIBC WMC, Inc. 
 425 Lexington Ave. 
 New York, NY 10017 
 Attn: Kathryn Casparian 
 Zhejiang Hisun Pharmaceutical Co., Ltd. 

Key Gate Investments Limited 
 China
Renaissance Capital Investment 
 Suite 305 St. George’s Building 
 2 Ice House Street 
 Central, Hong Kong 
 Hong Kong SAR 
 Attn: Andrew Lo 

 Exhibit B 

Key Ordinary Shareholders 

Jeffrey Yordon 
 812 Lakeland Drive

 Schaumburg, IL 60173 
 Lorin
Drake 
 4065 Walt Whitman Road 

St. Charles, IL 60175 
 Anthony J. Gulczynski

 1232 Eagle Crest Drive 
 Lemont,
IL 60439 
 Vivo Ventures Fund Cayman V, L.P. 
 c/o Vivo Ventures V, LLC 
 575 High Street, Suite 201 

Palo Alto, CA 94301 
 Attn: Chen Yu 

Vivo Ventures V Affiliates Fund, L.P. 

c/o Vivo Ventures V, LLC 
 575 High Street, Suite
201 
 Palo Alto, CA 94301 
 Attn: Chen
Yu 

 Exhibit C 

New Investors 
 Link
Best Capital Limited 
 Room 2201, 22/F., Far East Consortium Building 
 121, Des Voeux Road, 
 Central, Hong Kong. 
 Attn: Yap Shing Chi 
 Westfield Capital Management 

One Financial Center, 24th Floor 

Boston, MA 02111-2621 
 Attn: Matthew StrobeckSagent Holding Co. Series A Preference Shares Purchase Agreement

 Exhibit 10.11 
 SAGENT HOLDING CO. 
 SERIES A PREFERENCE SHARES PURCHASE AGREEMENT

 This Series A Preference Shares Purchase Agreement (the “Agreement”) is made and entered into as of
May 19, 2009 by and among Sagent Holding Co., a Cayman Islands exempted company (the “Company”), and each of the entities, severally and not jointly, listed on the Schedule of Purchasers attached hereto as
Exhibit A-1 (each, a “Purchaser,” and collectively, the “Purchasers”). 
 NOW
THEREFORE, in consideration of the mutual covenants and representations set forth herein, the Company and the Purchasers agree as follows: 
 1. Purchase and Sale of Shares. Subject to the terms and conditions of this Agreement, the Company hereby agrees to issue to the Purchasers and the Purchasers hereby agree to acquire from
the Company, severally and not jointly, up to an aggregate of Thirty Million (30,000,000) shares of the Company’s Series A Preference Shares (the “Shares” or “Series A Shares”) at a price of
US$1.00 per share (the “Purchase Price”). On or prior to the First Closing (as defined in Section 2(b) below), the Company shall have authorized (a) the sale and issuance to the Purchasers of the Shares, and (b) the
issuance of such Ordinary Shares (as defined in Section 4(d) below) to be issued upon conversion of the Shares (the “Conversion Shares”). The Shares and the Conversion Shares shall have the rights, preferences, privileges and
restrictions set forth in the Third Amended and Restated Memorandum of Association of the Company, as amended (the “Amended Memorandum”) and the Third Amended and Restated Articles of Association, as amended (the “Amended
Articles”) of the Company, in the forms attached hereto as Exhibit B-1 and Exhibit B-2, respectively. 
 2. Closings. 
 (a) Closings. The purchase, sale and
issuance of the Shares shall take place in multiple closings, the first closing to be held on the date hereof or at such time and on such date as designated by the Company and the Purchasers (the “First Closing”) and one or more
subsequent closings to be held within sixty days of the date of the First Closing (each, a “Subsequent Closing”) for the issuance and sale of up to the balance of Shares not sold in the First Closing; provided that each Subsequent
Closing shall be approved by the Company and the Purchasers that purchased a majority of the Shares issued in the First Closing. 
 (b) Closing Mechanics. The First Closing and each Subsequent Closing are each referred to herein as a “Closing,” and the date applicable to any such Closing, a
“Closing Date.” Each Closing will take place by facsimile or PDF, at the offices of Wilson Sonsini Goodrich & Rosati, P.C., or at such other place as shall be designated by the Company and agreed to by Purchasers who have
agreed to purchase a majority of the Shares to be issued hereunder at such Closing. At or before each Closing, the Company and the Purchasers in such Closing (as designated on Exhibit A-1 hereto) will execute counterpart signature pages
to this Agreement and the Amended 

 
Members Agreement, Amended Co-Sale Agreement and Amended Voting Agreement (each as defined in Section 4(a) below and together this Agreement, the “Agreements”). At or before
each Closing, each Purchaser shall deliver to the Company the aggregate Purchase Price of the Shares to be purchased by such Purchaser in such Closing, which is set forth opposite each Purchaser’s name in Exhibit A-1 hereto. The
payment shall be in the form of a cashier’s check, wire transfer of immediately available funds or cancellation of indebtedness. At each Closing, or as promptly thereafter as practicable, the Company will issue to each Purchaser a certificate
representing the Shares being purchased by such Purchaser in such Closing, as set forth opposite such Purchaser’s name in Exhibit A-1 hereto, registered in the name of such Purchaser. Upon delivery by each new Purchaser, if any, in
the Subsequent Closing of an executed counterpart signature page to this Agreement (and acceptance by the Company of such signature page), such Purchaser shall become a Party (as defined below) to this Agreement as a Purchaser with no further
amendment or action by any other Purchaser, and the Schedule of Purchasers attached hereto as Exhibit A-1 will be updated accordingly. 
 3. Purchaser’s Representations and Warranties. Each Purchaser hereby, severally and not jointly, represents and warrants to the Company as follows: 

(a) No Registration. The Purchaser understands that the Shares and the Conversion Shares, have not been, and will not
be, registered under the Securities Act of 1933, as amended (the “Securities Act”), by reason of a specific exemption from the registration provisions of the Securities Act, the availability of which depends upon, among other
things, the bona fide nature of the investment intent and the accuracy of each Purchaser’s representations as expressed herein or otherwise made pursuant hereto. 
 (b) Investment Intent. The Purchaser is acquiring the Shares and the Conversion Shares, for investment for its own account, not as a nominee or agent, and not with the view to, or for
resale in connection with, any distribution thereof, and that the Purchaser has no present intention of selling, granting any participation in, or otherwise distributing the same. The Purchaser further represents that it does not have any contract,
undertaking, agreement or arrangement with any person or entity to sell, transfer or grant participation to such person or entity or to any third person or entity with respect to any of the Shares or the Conversion Shares. 

(c) Investment Experience. The Purchaser, or its purchaser representative, within the meaning of Regulation D, Rule
501(h), promulgated by the Securities and Exchange Commission (its “Purchaser Representative”), has substantial experience in evaluating and investing in private placement transactions of securities in companies similar to the
Company and acknowledges that the Purchaser or its Purchaser Representative, can protect such Purchaser’s interests. The Purchaser or its Purchaser Representative has such knowledge and experience in financial and business matters so that the
Purchaser or its Purchaser Representative is capable of evaluating the merits and risks of its investment in the Company. 

(d) Speculative Nature of Investment. The Purchaser understands and acknowledges that the Company has a limited
financial and operating history and that an investment in the Company is highly speculative and involves substantial risks. The Purchaser can bear the economic risk of the Purchaser’s investment and is able, without impairing the
Purchaser’s financial condition, to hold the Shares and the Conversion Shares for an indefinite period of time and to suffer a complete loss of the Purchaser’s investment. 

  
 -2-

 (e) Access to Data. The Purchaser has had an opportunity to ask questions
of, and receive answers from, the officers of the Company concerning the Agreements, the exhibits and schedules attached hereto and thereto and the transactions contemplated by the Agreements, as well as the Company’s business, management and
financial affairs, which questions were answered to its satisfaction. The Purchaser understands that such discussions, as well as any information issued by the Company, were intended to describe certain aspects of the Company’s business and
prospects, but were not necessarily a thorough or exhaustive description. The Purchaser acknowledges that any business plans prepared by the Company have been, and continue to be, subject to change and that any projections included in such business
plans or otherwise are necessarily speculative in nature, and it can be expected that some or all of the assumptions underlying the projections will not materialize or will vary significantly from actual results. The Purchaser also acknowledges that
it is relying solely on its own counsel and not on any statements or representations of the Company or its agents for legal advice with respect to this investment or the transactions contemplated by the Agreements. 

(f) Accredited Investor. Unless the Purchaser is designated as a “Regulation S Investor” on
Exhibit A-2 hereto, such Purchaser is an “accredited investor” within the meaning of Regulation D, Rule 501(a), promulgated by the Securities and Exchange Commission under the Securities Act and shall submit to the Company such
further assurances of such status as may be reasonably requested by the Company. 
 (g) Residency. The
residency of the Purchaser (or, in the case of a partnership or corporation, such entity’s principal place of business) is correctly set forth on the Schedule of Purchasers. 

(h) Rule 144. The Purchaser acknowledges that the Shares and the Conversion Shares must be held indefinitely unless
subsequently registered under the Securities Act or an exemption from such registration is available. The Purchaser is aware of the provisions of Rule 144 promulgated under the Securities Act which permit resale of shares purchased in a private
placement subject to the satisfaction of certain conditions, which may include, among other things, the availability of certain current public information about the Company; the resale occurring not less than a specified period after a party has
purchased and paid for the security to be sold; the number of shares being sold during any three-month period not exceeding specified limitations; the sale being effected through a “brokers’ transaction,” a transaction directly with a
“market maker” or a “riskless principal transaction” (as those terms are defined in the Securities Act or the Securities Exchange Act of 1934, as amended, and the rules and regulations promulgated thereunder); and the filing of a
Form 144 notice, if applicable. The Purchaser understands that the current public information referred to above is not now available and the Company has no present plans to make such information available. The Purchaser acknowledges and
understands that notwithstanding any obligation under the Amended Members Agreement, the Company may not be satisfying the current public information requirement of Rule 144 at the time the Purchaser wishes to sell the Shares or the Conversion
Shares, and that, in such event, the Purchaser may be precluded from selling such securities under Rule 144, even if the other applicable requirements of Rule 144 have been satisfied. 

  
 -3-

 
The Purchaser acknowledges that, in the event the applicable requirements of Rule 144 are not met, registration under the Securities Act or an exemption from registration will be required for any
disposition of the Shares or the underlying Common Stock. The Purchaser understands that, although Rule 144 is not exclusive, the Securities and Exchange Commission has expressed its opinion that persons proposing to sell restricted securities
received in a private offering other than in a registered offering or pursuant to Rule 144 will have a substantial burden of proof in establishing that an exemption from registration is available for such offers or sales and that such persons and
the brokers who participate in the transactions do so at their own risk. 
 (i) No Public Market. The
Purchaser understands and acknowledges that no public market now exists for any of the securities issued by the Company and that the Company has made no assurances that a public market will ever exist for the Company’s securities. 

(j) Authorization.
 (i) The Purchaser has all requisite power and authority to execute and deliver the Agreements, to purchase the Shares hereunder and to carry out and perform its obligations under the terms of the
Agreements. All action on the part of the Purchaser necessary for the authorization, execution, delivery and performance of the Agreements, and the performance of all of the Purchaser’s obligations under the Agreements, has been taken or will
be taken prior to the Closing. 
 (ii) The Agreements, when executed and delivered by the Purchaser, will constitute valid and
legally binding obligations of the Purchaser, enforceable in accordance with their terms except: (i) to the extent that the indemnification provisions contained in the Amended Members Agreement may be limited by applicable law and principles of
public policy, (ii) as limited by applicable bankruptcy, insolvency, reorganization, moratorium and other laws of general application affecting enforcement of creditors’ rights generally, and (iii) as limited by laws relating to the
availability of specific performance, injunctive relief or other equitable remedies or by general principles of equity. 

(iii) No consent, approval, authorization, order, filing, registration or qualification of or with any court, governmental authority or
third person is required to be obtained by the Purchaser in connection with the execution and delivery of the Agreements by the Purchaser or the performance of the Purchaser’s obligations hereunder or thereunder. 

(k) Brokers or Finders. The Purchaser has not engaged any brokers, finders or agents, and neither the Company nor any
other Purchaser has, nor will, incur, directly or indirectly, as a result of any action taken by the Purchaser, any liability for brokerage or finders’ fees or agents’ commissions or any similar charges in connection with the Agreements.

 (l) Tax Advisors. The Purchaser has reviewed with its own tax advisors the U.S. federal, state, local and
foreign tax consequences of this investment and the transactions contemplated by the Agreements. With respect to such matters, the Purchaser relies solely on such advisors and not on any statements or representations of the Company or any of its
agents, written or oral. The Purchaser understands that it (and not the Company) shall be responsible for its own tax liability that may arise as a result of this investment or the transactions contemplated by the Agreements. 

  
 -4-

 (m) ERISA Status. If any Purchaser is a “benefit plan investor” (as
such term is defined in the regulations of the U.S. Department of Labor included within 29 C.F.R. section 2510.3-101) subject to the fiduciary responsibility provisions of part 4 of title I of the U.S. Employee Retirement Income Security Act of
1974, as amended from time to time (“ERISA”), such Purchaser shall indicate such status by writing “ERISA Purchaser” next to its name on Exhibit A-1 hereto. 

(n) Legends. The Purchaser understands and agrees that the certificates evidencing the Shares or the Conversion
Shares, or any other securities issued in respect of the Shares or the Conversion Shares upon any stock split, stock dividend, recapitalization, merger, consolidation or similar event, shall bear the following legend (in addition to any legend
required by the Ancillary Agreements or under applicable state securities laws): 
 “THE SECURITIES REPRESENTED HEREBY HAVE
NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”). SUCH SECURITIES MAY NOT BE TRANSFERRED UNLESS (A) A REGISTRATION STATEMENT UNDER THE ACT IS IN EFFECT AS TO SUCH TRANSFER OR (B) PURSUANT TO
RULE 144, OR (C) IN THE OPINION OF THE COMPANY, REGISTRATION UNDER THE ACT IS UNNECESSARY IN ORDER FOR SUCH TRANSFER TO COMPLY WITH THE ACT.” 
 (o) Investment Representations, Warranties and Covenants by Regulation S Investors. Each Purchaser that is designated as a Regulation S Investor on Exhibit A-2 hereby represents
and warrants to the Company as follows: 
 (i) This Agreement is made by the Company with the Purchaser, who is a
Non-U.S. person (as that term is defined in this Section 3(o)), in reliance upon such Non-U.S. person’s representations, warranties and covenants made in this Section 3(o). 

(ii) Such Non-U.S. person has been advised and acknowledges that: 

(1) the Shares and the Conversion Shares have not been, and when issued, will not be registered under the Securities Act, the
securities laws of any state of the United States or the securities laws of any other country; 
 (2) in issuing and
selling the Shares and the Conversion Shares to such Non-U.S. person pursuant hereto, the Company is relying upon the “safe harbor” provided by Regulation S and/or on Section 4(2) under the Securities Act; 

(3) it is a condition to the availability of the Regulation S “safe harbor” that the Shares and the Conversion Shares
not be offered or sold in the United States or to a U.S. person until the expiration of a one-year “distribution compliance period” (or a six-month “distribution compliance period,” if the issuer is a “reporting
issuer,” as defined in Regulation S) following the Closing Date; and 

  
 -5-

 (4) notwithstanding the foregoing, prior to the expiration of the one-year
“distribution compliance period” (or six-month “distribution compliance period,” if the issuer is a “reporting issuer,” as defined in Regulation S) after the Closing (the “Restricted Period”), the
Shares and the Conversion Shares may be offered and sold by the holder thereof only if such offer and sale is made in compliance with the terms of this Agreement and either: (A) if the offer or sale is within the United States or to or for the
account of a U.S. person (as such terms are defined in Regulation S), the securities are offered and sold pursuant to an effective registration statement or pursuant to Rule 144 under the Securities Act or pursuant to an exemption from the
registration requirements of the Securities Act; or (B) the offer and sale is outside the United States and to other than a U.S. person. 
 (iii) As used herein, the term “United States” means the United States of America, its territories and possessions, any State of the United States, and the District of Columbia,
and the term “U.S. person” (as defined in Regulation S) means: 
 (1) a natural person resident in the
United States; 
 (2) any partnership or corporation organized or incorporated under the laws of the United States;

 (3) any estate of which any executor or administrator is a U.S. person; 

(4) any trust of which any trustee is a U.S. person; 
 (5) any agency or branch of a foreign entity located in the United States; 

(6) any nondiscretionary account or similar account (other than an estate or trust) held by a dealer or other fiduciary for the
benefit or account of a U.S. person; 
 (7) any discretionary account or similar account (other than an estate or trust)
held by a dealer or other fiduciary organized, incorporated and (if an individual) resident in the United States; and 
 (8)
a corporation or partnership organized under the laws of any foreign jurisdiction and formed by a U.S. person principally for the purpose of investing in securities not registered under the Securities Act, unless it is organized or incorporated,
and owned, by accredited investors (as defined in Rule 501(a) under the Securities Act) who are not natural persons, estates or trusts. 
 As used herein, the term “Non-U.S. person” means any person who is not a U.S. person or is deemed not to be a U.S. person under Rule 902(k)(2) of the Securities Act. 

(iv) Such Non-U.S. person agrees that with respect to the Shares and the Conversion Shares, until the expiration of the
Restricted Period: 
 (1) such Non-U.S. person, its agents or its representatives have not and will not solicit offers
to buy, offer for sale or sell any of the Shares and the Conversion Shares, or any beneficial interest therein in the United States or to or for the account of a U.S. person; and 

  
 -6-

 (2) notwithstanding the foregoing, the Shares and the Conversion Shares may be
offered and sold by the holder thereof only if such offer and sale is made in compliance with the terms of this Agreement and either: (A) if the offer or sale is within the United States or to or for the account of a U.S. person (as such terms
are defined in Regulation S), the securities are offered and sold pursuant to an effective registration statement or pursuant to Rule 144 under the Securities Act or pursuant to an exemption from the registration requirements of the Securities Act;
or (B) the offer and sale is outside the United States and to other than a U.S. person; and 
 (3) such Non-U.S.
person shall not engage in hedging transactions with regard to the Shares and the Conversion Shares unless in compliance with the Securities Act. 
 The foregoing restrictions are binding upon subsequent transferees of the Shares and the Conversion Shares, except for transferees pursuant to an effective registration statement. Such Non-U.S. person
agrees that after the Restricted Period, the Shares and the Conversion Shares may be offered or sold within the United States or to or for the account of a U.S. person only pursuant to applicable securities laws. 

(v) Such Non-U.S. person has not engaged, nor is it aware that any party has engaged, and such Non-U.S. person will not engage or
cause any third party to engage, in any directed selling efforts (as such term is defined in Regulation S) in the United States with respect to the Shares and the Conversion Shares. 

(vi) Such Non-U.S. person: (i) is domiciled and has its principal place of business outside the United States;
(ii) certifies it is not a U.S. person and is not acquiring the Shares or the Conversion Shares for the account or benefit of any U.S. person; and (iii) at the time of the Closing Date, the Non-U.S. person or persons acting on Non-U.S.
person’s behalf in connection therewith will be located outside the United States. 
 (vii) At the time of offering
to such Non-U.S. person and communication of such Non-U.S. person’s order to purchase the Shares or the Conversion Shares and at the time of such Non-U.S. Person’s execution of this Agreement, the Non-U.S. person was located outside the
United States. 
 (viii) Such Non-U.S. person is not a “distributor” (as defined in Regulation S) or a
“dealer” (as defined in the Securities Act). 
 (ix) Such Non-U.S. person acknowledges that the Company shall
make a notation in its stock books regarding the restrictions on transfer set forth in this Section 3(o) and shall transfer such shares on the books of the Company only to the extent consistent therewith. 

  
 -7-

 In particular, such Non-U.S. person acknowledges that the Company shall refuse to register
any transfer of the Shares or the Conversion Shares not made in accordance with the provisions of Regulation S, pursuant to registration under the Securities Act or pursuant to an available exemption from registration. 

(x) Such Purchaser understands and agrees that each certificate held by such Non-U.S. person representing the Shares or the
Conversion Shares, or any other securities issued in respect of the Shares or any the Conversion Shares upon conversion thereof upon any stock split, stock dividend, recapitalization, merger, consolidation or similar event, shall bear the following
legend (in addition to any legend required by the Ancillary Agreement or under applicable state securities laws): 
 THE
SECURITIES REPRESENTED HEREBY HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND MAY NOT BE SOLD, TRANSFERRED, ASSIGNED, PLEDGED OR HYPOTHECATED EXCEPT IN ACCORDANCE WITH THE PROVISIONS
OF REGULATION S PROMULGATED UNDER THE SECURITIES ACT, PURSUANT TO REGISTRATION UNDER THE SECURITIES ACT OR PURSUANT TO AN AVAILABLE EXEMPTION FROM REGISTRATION. HEDGING TRANSACTIONS INVOLVING THE SHARES REPRESENTED HEREBY MAY NOT BE CONDUCTED UNLESS
IN COMPLIANCE WITH THE SECURITIES ACT. THIS CERTIFICATE MUST BE SURRENDERED TO THE COMPANY OR ITS TRANSFER AGENT AS A CONDITION PRECEDENT TO THE SALE, PLEDGE, HYPOTHECATION OR ANY OTHER TRANSFER OF ANY INTEREST IN ANY OF THE SHARES REPRESENTED BY
THIS CERTIFICATE. 
 (p) Representations by Non-United States persons. If a Purchaser is not a United States
person, the Purchaser hereby represents that the Purchaser is satisfied as to the full observance of the laws of the Purchaser’s jurisdiction in connection with any invitation to subscribe for the Shares and the Conversion Shares or any use of
the Agreements, including (i) the legal requirements within the Purchaser’s jurisdiction for the purchase of the Shares and the Conversion Shares, (ii) any foreign exchange restrictions applicable to such purchase, (iii) any
governmental or other consents that may need to be obtained and (iv) the income tax and other tax consequences, if any, that may be relevant to the purchase, holding, redemption, sale or transfer of such securities. The Purchaser’s
subscription and payment for, and the Purchaser’s continued beneficial ownership of, the Shares and the Conversion Shares will not violate any applicable securities or other laws of the Purchaser’s jurisdiction. 

4. Company’s Representations. Except as set forth in the Schedule of Exceptions attached hereto as
Schedule A, the Company hereby represents, warrants and covenants to each Purchaser as of the applicable Closing Date as set forth below. Except for Sections (a), (b), (c), (d), (e) and (f) below, for purposes of this
Section 4, all references to the “Company” shall refer to and include the Company and its wholly owned subsidiaries, Sagent International, a Cayman Islands exempted company (the “Cayman Sub”), and Sagent
Pharmaceuticals, a Wyoming corporation (the “Wyoming Sub”) (each, a “Subsidiary” and together, the “Subsidiaries”). 

  
 -8-

 (a) Corporate Power. The Company presently has, and as of the Closing will
have, full legal right, power and capacity and all necessary consents, approvals and authorizations, whether corporate, member, governmental or otherwise, as may be required to execute and deliver this Agreement and the related ancillary agreements
(the “Ancillary Agreements,” which include the Amended and Restated Members Agreement (the “Amended Members Agreement”), in the form attached hereto as Exhibit C, the Amended and Restated Right of First
Refusal and Co-Sale Agreement (the “Amended Co-Sale Agreement”), substantially in the form attached hereto as Exhibit D, and the Amended and Restated Voting Agreement (the “Amended Voting Agreement”),
substantially in the form attached hereto as Exhibit E), to issue and sell the Shares and the Conversion Shares to each Purchaser pursuant hereto in the manner contemplated hereby and to carry out the provisions of this Agreement, the
Ancillary Agreements and the Amended Articles. 
 (b) Organization, Good Standing and Qualification. The Company
is an exempted company duly incorporated, validly existing and in good standing under the laws of the Cayman Islands, and is qualified and is authorized to do business as a foreign corporation in all jurisdictions where the failure to be so
qualified and/or authorized would have a material adverse effect on the business, assets, properties, prospects, results of operations and financial condition of the Company and its Subsidiaries, taken as a whole (a “Material Adverse
Effect”). The Company has all requisite corporate power and authority to own and operate its business, properties and assets and to carry on its business as presently conducted and as presently proposed to be conducted. 

(c) Subsidiaries. Except for the Cayman Sub and the Wyoming Sub, both of which are wholly owned subsidiaries, the Company
does not own or control, directly or indirectly, or hold any rights to acquire any equity security or other interest of any other corporation, limited partnership or other business entity. Except as set forth in the Schedule of Exceptions, the
Company is not a participant in any joint venture, partnership or similar arrangement. Each Subsidiary is duly organized and existing under the laws of its jurisdiction of incorporation and is in good standing under such laws, and all of the
outstanding shares, including shares of capital stock (or other voting interests), in each Subsidiary are owned by the Company. Each Subsidiary does not own or lease property or engage in any activity in any jurisdiction that might require its
qualification to do business as a foreign corporation and in which the failure so to qualify would have a Material Adverse Effect. 
 (d) Capitalization. Immediately prior to the First Closing, the authorized capital of the Company consists of: 
 (i) Preference Shares. One Hundred Thirteen Million (113,000,000) Preference Shares of the Company, par value US$0.00001 per share (“Preference Shares”), all of which
are designated as Series A Shares and 83,000,000 of which are issued and outstanding. The rights, privileges and preferences of the Series A Shares are as stated in the Amended Articles. 

  
 -9-

 (ii) Ordinary Shares. One Hundred Sixty Four Million Four Hundred Thousand
(164,400,000) Ordinary Shares of the Company, par value US$0.00001 per share (“Ordinary Shares”), of which (A) 15,569,001 shares are issued and outstanding, and (B) One Hundred Thirteen Million
(113,000,000) shares have been reserved for issuance upon conversion of the Series A Shares. The Company has reserved Thirteen Million Two Hundred Thousand (13,200,000) of its Ordinary Shares to be granted to employees, consultants
and directors pursuant to the Company’s 2007 Global Share Plan (the “Option Plan”). There are currently Six Million Three Hundred Thirteen Thousand Two Hundred Fifty Six (6,313,256) options outstanding to purchase Ordinary
Shares under the Option Plan. The outstanding Ordinary Shares (and, with respect to the following Clauses 2 and 3 of this Section d(ii), the outstanding options for Ordinary Shares) (1) have been duly authorized and validly issued,
and are fully paid and nonassessable, (2) were issued in compliance with all applicable state, foreign and federal laws concerning the issuance of securities, and (3) were not issued in violation of any applicable statutory, contractual or
other preemptive rights, pro rata rights, rights of first refusal or similar rights. All options granted or pledged to be granted and Ordinary Shares issued vest as follows: twenty-five percent (25%) of the shares vest one (1) year
following the vesting commencement date, with the remaining seventy-five percent (75%) vesting in equal monthly installments over the next three (3) years. Except as set forth in the Schedule of Exceptions, no share plan, share purchase,
share option or other agreement or understanding between the Company and any holder of any equity securities or rights to purchase equity securities provides for acceleration or other changes in the vesting provisions or other terms of such
agreement or understanding as the result of (i) termination of employment or consulting services (whether actual or constructive); (ii) any merger, consolidated sale of shares or assets, change in control or any other transaction(s) by the
Company; or (iii) the occurrence of any other event or combination of events 
 (iii) Except as otherwise set forth
herein or in the Ancillary Agreements, there are no outstanding options, warrants, rights (including conversion or preemptive rights and rights of first refusal), proxy or member agreements or agreements of any kind to purchase any of the
Company’s authorized and unissued shares. 
 (iv) Purchasers who are subject to ERISA (as previously described
herein) will not at any time own 25% or more of the Series A Shares and/or the Ordinary Shares then currently issued. 
 (v)
Each Series A Share is convertible into an Ordinary Share on a one-for-one basis as of the date hereof. The Conversion Shares have been duly and validly reserved for issuance. When issued in compliance with the provisions of this Agreement
and the Amended Articles, the Shares and the Conversion Shares will be validly issued, fully paid and nonassessable, and will be free of any liens or encumbrances other than liens and encumbrances created by or imposed upon the Purchasers;
provided, however, that the Shares and the Conversion Shares may be subject to restrictions on transfer under the terms of this Agreement and the Ancillary Agreements, and under applicable state, federal and/or foreign securities laws.
No provisions of applicable law (including any laws of the Cayman Islands) or the Amended Articles gives the Company the right to make any capital call or similar demand for contributions from any member of the Company. 

The terms “reserve,” “reservation” or similar words have no technical meaning under the Companies Law (2007 Revision)
of the Cayman Islands. For the purpose only of this Agreement, “reserve,” “reservation” or similar words shall mean that the Company shall and the Board of 

  
 -10-

 
Directors shall procure that the Company shall refrain from issuing (i) a number of Series A Shares sufficient to enable the Company to comply with its obligations pursuant to this
Agreement so that such number of Series A Shares will remain in the authorized but unissued share capital of the Company until the rights to purchase the Series A Shares are exercised in accordance with the terms of this Agreement, and
(ii) a number of Ordinary Shares sufficient to satisfy the conversion rights of the holders of Series A Shares and the purchase rights of the holders of options to purchase Ordinary Shares, so that such number of Ordinary Shares will
remain in the authorized but unissued share capital of the Company until the aforementioned conversion and/or purchase rights are exercised in accordance with the terms of the Amended Articles or the Option Plan (and the related option agreements),
as applicable. 
 (vi) All holders of outstanding securities of the Company, including, without limitation, all
outstanding shares of the Company, all shares of the Company issuable upon the conversion or exercise of all convertible or exercisable securities and all other securities that the Company is obligated to issue, are subject to a one hundred eighty
(180) day “market stand-off” restriction upon an initial public offering of the Company’s securities pursuant to a registration statement filed with the SEC pursuant to the Act in a form no less restrictive to such holder than
that contained in the Amended Members Agreement. 
 (e) Enforceability. This Agreement and the Ancillary
Agreements, when executed and delivered by the Company, will be duly and validly executed and delivered by the Company and will constitute the Company’s legally binding obligations enforceable against the Company in accordance with their terms,
except to the extent that such enforcement may be limited by bankruptcy, insolvency or similar laws now or hereafter in effect relating to creditors’ rights and remedies generally. All corporate action on the part of the Company, its officers,
directors and members necessary for the authorization of this Agreement and the Ancillary Agreements, the performance of all obligations of the Company hereunder and thereunder at the Closing and the authorization, sale, issuance and delivery of the
Shares pursuant hereto and the Conversion Shares pursuant to the Amended Articles has been taken or will be taken prior to the Closing. The sale of the Shares and the subsequent conversion of the Shares into Conversion Shares are not and will not be
subject to any preemptive rights or rights of first refusal that have not been properly waived or complied with. 
 (f)
Offering. Provided that the representations and warranties made by each Purchaser herein are complete, true and accurate, then the offer, issuance and sale of the Shares and the Conversion Shares pursuant to this Agreement will be exempt
from the registration requirements of the Act, and are exempt from registration and qualification under the registration, permit or qualification requirements of all applicable United States state and foreign securities laws. 

(g) Financial Statements. The Company has delivered to the Purchasers and/or a Purchaser’s investment manager the
unaudited consolidated balance sheet, income statement and cash flow statement of the Company as of and for the year ended December 31, 2008 (the “Balance Sheet Date”) (the foregoing financial statements and notes thereto, as
applicable, are hereinafter referred to as the “Financial Statements”). The Financial Statements are correct in all material respects, present fairly the financial condition and operating results of the Company as of the date(s) and
during the period(s) indicated therein and were prepared in accordance with United States generally accepted accounting principles. 

  
 -11-

 (h) Changes. Since Balance Sheet Date, there has not been any event or
condition of any type that has had or that the Company expects to have a Material Adverse Effect. 
 (i) Title to
Property and Assets. The Company has good and marketable title to its property and assets, and has good title to all its leasehold interests, in each case subject to no mortgage, pledge, lien, lease, encumbrance or charge that materially
detracts from the value of the property subject thereto or materially impairs the operations of the Company. All facilities, machinery, equipment, fixtures, vehicles and other properties owned, leased or used by the Company that are material to the
business of the Company are in good operating condition and repair, normal wear and tear excepted, and are reasonably fit and usable for the purposes for which they are being used. The Company is in compliance with all material terms of each lease
to which it is a party or is otherwise bound. 
 (j) Litigation. There is no action, suit, proceeding or
investigation pending or, to the knowledge of the Company, currently threatened against the Company. There is no action, suit, proceeding or investigation by the Company currently pending or which the Company intends to initiate. 

(k) Intellectual Property Rights. The Company owns, or has the right to use (or can obtain the right to use on reasonable
commercial terms), all copyrights, licenses, trade secrets, mask works or other proprietary rights, and, to the knowledge of the Company, without having conducted any special investigation or patent search, all patents, trademarks, service names,
and trade names, necessary to its business as now conducted or presently proposed to be conducted without any infringement of the rights of others. The Company has not received any written communication of any pending infringement claims regarding
any third party’s patents, copyrights, trademarks, trade secrets or proprietary rights and processes against the Company. The Company is not aware of any violation by a third party of any of its patents, copyrights, trademarks, trade secrets or
other proprietary rights. The Company has taken reasonable security measures to protect the secrecy, confidentiality and value of its proprietary information and the Company is not aware that any of its employees is obligated under any contract
(including licenses, covenants or commitments of any nature) or other agreement, or subject to any judgment, decree or order of any court or administrative agency, that would interfere with their duties to the Company or that would conflict with the
Company’s business as proposed to be conducted. 
 (l) Proprietary Information and Invention Assignment. Each
employee and technical consultant (e.g., other than professional service providers such as accountants and attorneys) of the Company has executed a confidential information and invention assignment agreement substantially in the form(s) previously
delivered to counsel to the Purchasers. No former or current employee or technical consultant of the Company has excluded works or inventions made prior to such person’s employment or consultancy with the Company from such person’s
assignment of inventions pursuant to such confidential information and inventions agreement. 

  
 -12-

 (m) Liabilities. Except as set forth in the Financial Statements, the Company
has no material liabilities, contingent or otherwise, except current liabilities incurred in the ordinary course of business since the Balance Sheet Date which have not caused and are not expected to cause a Material Adverse Effect. 

(n) Compliance with Other Instruments. The Company is not in violation or default of any term of the Amended Memorandum or
Amended Articles, or in any material respect of any provision of any material mortgage, indenture, agreement, instrument or contract to which it is party or by which it is bound or of any judgment, decree, order or writ. The execution, delivery, and
performance of and compliance with this Agreement, and the Ancillary Agreements, and the issuance and sale of the Shares pursuant hereto, and of the Conversion Shares pursuant to the Amended Articles, will not, with or without the passage of time or
giving of notice, (i) result in any such violation, (ii) be in conflict with or constitute a default under any such term, or (iii) result in the creation of any mortgage, pledge, lien, encumbrance or charge upon any of the properties
or assets of the Company or the suspension, revocation, impairment, forfeiture or nonrenewal of any permit, license, authorization or approval applicable to the Company, its business or operations or any of its assets or properties. The Company has
not performed any act or omitted any act, the occurrence or omission of which would result in the Company’s loss of any right granted under any license, distribution agreement or other agreement required to be disclosed on the Schedule of
Exceptions, whereby the loss of such right would have a Material Adverse Effect. 
 (o) Agreements. 

(i) Except for the agreements contemplated hereby and agreements between the Company and its employees with respect to sales of
Ordinary Shares and confidentiality and invention assignment agreements, there are no agreements, understandings or proposed transactions between the Company and any of its officers, directors, affiliates, or any affiliate thereof. There are no
obligations of the Company to officers, directors, member, or employees of the Company other than (a) for payment of salary for services rendered, (b) reimbursement for reasonable expenses incurred on behalf of the Company and (c) for
other standard employee benefits made generally available to all employees (including stock option agreements outstanding under any share option plan approved by the Board). None of the officers, directors, key employees or members of the Company is
indebted to the Company. None of the officers, directors, or, to the best of the Company’s knowledge, key employees or members of the Company or any members of their immediate families, has any direct or indirect ownership interest in any firm
or corporation with which the Company is affiliated or with which the Company has a business relationship, or any firm or corporation that competes with the Company, other than (i) passive investments in publicly traded companies (representing
less than 1% of such company) which may compete with the Company and (ii) service as a board member of a Company due to a person’s affiliation with a venture capital fund or similar institutional investor in such Company. No officer,
director or member, or any member of their immediate families, is, directly or indirectly, interested in any material contract with the Company (other than such contracts as relate to any such person’s ownership of share capital or other
securities of the Company). The Company is not a guarantor or indemnitor of any indebtedness of any third party. 

  
 -13-

 (ii) There are no agreements, understandings, instruments, contracts, proposed
transactions, judgments, orders, writs or decrees to which the Company is a party or by which it is bound that may involve (1) obligations (contingent or otherwise) of, or payments by the Company in excess of, US$250,000, (2) the license
of any patent, copyright, trade secret or other proprietary right to or from the Company, (3) the granting of any rights affecting the development, manufacture, licensing, marketing, sale or distribution of the Company’s products or
services, or (4) indemnification by the Company with respect to infringements of proprietary rights. 
 (p)
Taxes. The Company has timely filed all tax returns and reports as required by law. These returns and reports are true and correct in all material respects. The Company has paid all taxes and other assessments due. 

(q) Governmental Consents. Subject in part to information provided by the Purchasers, no consent, approval, order or
authorization of, or registration, qualification, designation, declaration or filing with, any United States federal, state or local or Cayman Islands governmental authority on the part of the Company is required in connection with the consummation
of the transactions contemplated by this Agreement, except for filings pursuant to applicable United States state securities or blue sky laws and/or filings pursuant to Regulation D under the Act. 

(r) Registration Rights. Except as set forth in the Amended Members Agreement, the Company is not under any obligation and
has not granted any rights to register under the Act any of its presently outstanding securities or any of its securities that may hereafter be issued. 
 (s) Permits. The Company has all franchises, permits, licenses, and any similar authority necessary for the conduct of its business as now being conducted by it, the lack of which would have
a Material Adverse Effect, and believes it can obtain, without undue burden or expense, any similar authority for the conduct of its business as presently planned to be conducted. The Company is not in default in any material respect under any
of such franchises, permits, licenses or other similar authority. 
 (t) Employees. The Company has no collective
bargaining agreements with any of its employees. There is no labor union organizing activity pending or, to the Company’s knowledge, threatened with respect to the Company. The Company is not a party to or bound by any currently effective
employment contract, deferred compensation arrangement, bonus plan, incentive plan, profit sharing plan, retirement agreement or other employee compensation plan or agreement, other than the Plan and option grants thereunder. No employee of the
Company has been granted the right to continued employment by the Company or to any material compensation following termination of employment with the Company. To the Company’s knowledge, no employee of the Company, nor any consultant with whom
the Company has contracted, is in violation of any term of any employment contract, proprietary information agreement or any other agreement relating to the right of any such individual to be employed by, or to contract with, the Company because of
the nature of the business to be conducted by the Company; and to the Company’s knowledge the continued employment by the Company of its present employees, and the performance of the Company’s contracts with its independent contractors,
will not result in any such violation. The Company has not received any notice alleging that any such violation has occurred. No employee of 

  
 -14-

 
the Company has been granted the right to continued employment by the Company or to any material compensation following termination of employment with the Company. The Company is not aware that
any officer, or key employee, or that any group of key employees, intends to terminate his, her or their employment with the Company, nor does the Company have a present intention to terminate the employment of any officer, key employee or group of
key employees. 
 (u) Brokers or Finders. The Company has not incurred, and will not incur, directly or
indirectly, as a result of any action taken by the Company, any liability for brokerage or finders’ fees or agents’ commissions or any similar charges in connection with this Agreement or any of the transactions contemplated hereby.

 (v) Obligations of Management. Each officer and key employee of the Company is currently devoting substantially
all of his business time to the conduct of the business of the Company. The Company is not aware that any officer or key employee of the Company is planning to work less than full time at the Company in the future. No officer or key employee is
currently working or, to the Company’s knowledge, plans to work for a competitive enterprise, whether or not such officer or key employee is or will be compensated by such enterprise. 

(w) Disclosure. To the Company’s knowledge, (a) none of the Agreement or Ancillary Agreements, when taken as a
whole, or any other document delivered by the Company to Purchasers in connection with the Agreement or Ancillary Agreements, contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements contained
herein or therein not misleading in light of the circumstances under which they were made and (b) its offering and accepting payment for the Shares will not violate any applicable securities or other laws of the Company’s or any
Purchaser’s jurisdiction. The Company does not represent or warrant that it will achieve any financial projections provided to the Purchasers and represents only that such projections were prepared in good faith. 

5. Conditions to Closing of Purchasers. Unless otherwise specifically stated, each Purchaser’s obligation to purchase
the Shares at the applicable Closing, is, at the option of each Purchaser, subject to the fulfillment of the following conditions: 
 (a) Representations and Warranties. The representations and warranties made by the Company in Section 4 hereof shall be true and correct in all material respects as of the applicable
Closing Date with the same force and effect as if they had been made as of such Closing Date, and the Company shall have performed or complied with all obligations and conditions herein required to be performed or complied with by it on or prior to
the Closing. 
 (b) Covenants. All covenants, agreements and conditions contained in this Agreement to be
performed by the Company on or prior to the Closing shall have been complied with or performed. 
 (c)
Qualifications. All authorizations, approvals or permits, if any, of any governmental authority or regulatory body of the United States, of any state or foreign body that are required in connection with the lawful issuance and sale of the
Shares pursuant to the Agreement and the Ancillary Agreements shall be duly obtained and effective as of the applicable Closing Date, except for such as may be properly obtained subsequent to the Closing. 

  
 -15-

 (d) Memorandum and Articles of Association. The Amended Memorandum and the
Amended Articles shall have been approved by all of the members of the Company on or prior to the applicable Closing Date and shall be in full force and effect as of the applicable Closing Date. 

(e) Compliance Certificate. The Company shall have delivered to the Purchasers a Compliance Certificate, executed by the
President of the Company, dated the applicable Closing Date, to the effect that the conditions specified in subsections (a) and (b) of this Section 5 have been satisfied. 

(f) Secretary’s Certificate. The Purchasers and/or their investment manager (as applicable) shall have received from
the Company’s Secretary, a certificate having attached thereto (i) the Amended Memorandum and the Amended Articles as in effect at the time of the Closing, (ii) resolutions approved by the Board of Directors authorizing the
transactions contemplated hereby, (iii) resolutions approved by the Company’s members adopting the Amended Articles and authorizing the filing of the Amended Memorandum and the Amended Articles, and (iv) good standing certificates
with respect to the Company from the applicable authority(ies) in the Cayman Islands, dated a recent date before the Closing. 

(g) Board of Directors. Effective as of the First Closing, the directors of the Company shall be Jeffrey Yordon, Frank
Kung, Chen Yu, James Sperans, and Robert Flanagan. 
 (h) Members Agreement. The Company, the Purchasers and
certain members of the Company shall have entered into the Amended Members Agreement. 
 (i) Right of First Refusal
and Co-Sale Agreement. The Company, the Purchasers and certain members of the Company shall have entered into the Amended Co-Sale Agreement. 
 (j) Voting Agreement. The Company, the Purchasers and certain members of the Company shall have entered into the Amended Voting Agreement. 

(k) Legal Opinions. For the First Closing only, the Purchaser and/or their investment manager (as applicable) shall have
received from Wilson Sonsini Goodrich & Rosati, P.C., United States counsel to the Company, and Maples and Calder, Cayman Islands counsel to the Company, opinions addressed to each Purchaser respectively, each dated as of the First Closing,
in substantially the forms attached hereto as Exhibit F-1 and Exhibit F-2, respectively. 
 (l)
Budget. Prior to the First Closing, the Company’s 2009 and 2010 pro forma budgets shall have been approved by the Board of Directors of the Company, including the approval of at least two (2) directors nominated or elected by
the holders of Series A Preference Shares. 
 6. Conditions to Closing of the Company. The Company’s
obligation to sell and issue the Shares to each Purchaser at the applicable Closing is, at the option of the Company, subject to the fulfillment as of the applicable Closing Date of the following conditions: 

(a) Representations and Warranties Correct. The representations and warranties made severally by each Purchaser in
Section 3 hereof shall be true and correct in all material respects when made, and shall be true and correct on the applicable Closing Date, and each such Purchaser shall have performed or complied with all obligations and conditions herein
required to be performed or complied with by it on or prior to the Closing. 

  
 -16-

 (b) Qualifications. All authorizations, approvals or permits, if any, of any
governmental authority or regulatory body of the United States, of any state or foreign body that are required in connection with the lawful issuance and sale of the Shares pursuant to the Agreement and the Ancillary Agreements shall be duly
obtained and effective as of the applicable Closing Date, except for such as may be properly obtained subsequent to the Closing. 
 (c) Memorandum and Articles of Association. The Amended Memorandum and the Amended Articles shall have been approved by the members of the Company on or prior to the applicable Closing Date
and shall be in full force and effect as of the applicable Closing Date. 
 (d) Members Agreement. The Company,
the Purchasers and certain members of the Company shall have entered into the Amended Members Agreement. 
 (e) Right
of First Refusal and Co-Sale Agreement. The Company, the Purchasers and certain members of the Company shall have entered into the Amended Co-Sale Agreement. 
 (f) Voting Agreement. The Company, the Purchasers and certain members of the Company shall have entered into the Amended Voting Agreement. 

7. Miscellaneous. 
 (a) Intent. The parties hereto (each, a “Party” and collectively, the “Parties”) agree to execute such further instruments and to take such further action
as may reasonably be necessary to carry out the intent of this Agreement. 
 (b) Expenses. The Company agrees to
reimburse the reasonable legal fees and disbursements incurred by a single legal counsel for the Purchasers in connection with the transactions hereof in the aggregate not to exceed US$30,000.00. 

(c) Notices. All notices and other communications required or permitted hereunder shall be in writing and shall be sent by
facsimile or mailed by electronic, registered or certified mail or by overnight courier or otherwise delivered by hand or by messenger, addressed: 
 (i) if to a Purchaser, at the Purchaser’s address, as shown on Exhibit A-1 hereto, or at such other address as the Purchaser shall have furnished to the Company in writing,

  
 -17-

 (ii) if to the Company, at the address of the Company’s principal corporate
offices to the attention of President, or at such other address as the Company shall have furnished to the Purchasers in writing, 
 with a copy to: 
 Carmen Chang 

Wilson Sonsini Goodrich &Rosati, P.C. 
 650 Page Mill Road 
 Palo Alto, CA 94304 

Facsimile: (650) 493-6811 
 Email: cchang@wsgr.com 
 Where a notice is sent by mail, service of the notice
shall be effected by properly addressing, pre-paying and mailing a letter containing the notice, and to have been effected at the expiration of three (3) business days after the letter containing the same is mailed as aforesaid. 

Where a notice is sent by overnight courier, service of the notice shall be effected by properly addressing, and sending such notice
through an internationally recognized express courier service, delivery fees pre-paid, and to have been effected three (3) business days following the day the same is sent as aforesaid. 

Where a notice is delivered by electronic mail, by hand or by messenger, service of the notice shall be deemed to be effected upon
delivery. 
 (d) Successors and Assigns. Except as otherwise expressly provided herein, the provisions hereof
shall inure to the benefit of, and be binding upon, the successors, assigns, heirs, executors and administrators of the Parties. 
 (e) Amendment. This Agreement may be amended by a written instrument executed by the Company and the Purchasers who hold a majority of the Shares issued pursuant hereto, provided that
any amendment that, by its terms, treats any Purchaser or group of Purchasers in a materially adverse manner that is different than any other Purchaser will require the separate approval of such Purchaser or a majority in interest of such group of
Purchasers. 
 (f) Governing Law. This Agreement shall be governed by, and construed and enforced in accordance
with, the internal laws of the State of California as such laws are applied to agreements between California residents entered into and to be performed within California. Each of the Parties hereto irrevocably: (i) agrees that any dispute or
controversy arising out of, relating to, or concerning any interpretation, construction, performance or breach of this Agreement, shall be settled by arbitration to be held in Santa Clara County, California, in accordance with the rules then in
effect of the American Arbitration Association; (ii) waives, to the fullest extent it may effectively do so, any objection which it may now or hereafter have to the laying of venue of any such arbitration; and (iii) submits to the
exclusive jurisdiction of the State of California in any such arbitration. The decision of the arbitrator shall be final, conclusive and binding on the Parties to the arbitration. Judgment may be entered on the arbitrator’s decision in any
court having jurisdiction. 

  
 -18-

 
The Parties to the arbitration shall each pay an equal share of the costs and expenses of such arbitration, and each Party shall separately pay for its respective counsel fees and expenses;
provided, however, that the prevailing Party in any such arbitration shall be entitled to recover from the non-prevailing Party its reasonable costs and attorney fees. 
 (g) Specific Enforcement. Except as otherwise provided herein, any and all remedies expressly conferred upon a Party by this Agreement will be deemed cumulative with and not exclusive of any
other remedy conferred hereby, or by law or equity upon such Party, and the exercise by a Party of any one remedy will not preclude the exercise of any other remedy. The Parties agree that irreparable damage may occur in the event that any of the
provisions of this Agreement were not performed in accordance with their specific terms or were otherwise breached. It is accordingly agreed that the Parties shall be entitled to jointly or severally seek an injunction or injunctions to prevent
breaches of this Agreement and to enforce specifically the terms and provisions hereof in any federal or state court in the State of California, this being in addition to any other remedy to which they are entitled at law or in equity. 

(h) Survival: The representations, warranties, covenants and agreements made herein shall survive any investigation made by
any Purchaser and the closing of the transactions contemplated hereby for one (1) year. All statements as to factual matters contained in any certificate or other instrument delivered by or on behalf of the Company pursuant to
Sections 5(e) and 5(f) hereof shall be deemed to be representations and warranties by the Company hereunder solely as of the date of such certificate or instrument. 
 (i) Broker’s Fees. Each Party severally represents and warrants that no agent, broker, investment banker, person or firm acting on behalf of or under the authority of such Party is or
will be entitled to any broker’s or finder’s fee or any other commission directly or indirectly in connection with the transactions contemplated herein. Each Party further agrees to indemnify each other Party for any claims, losses or
expenses incurred by such other Party as a result of the representation in this Section 7(i) being untrue. 
 (j)
Exculpation Among Purchasers. Each Purchaser acknowledges that it is not relying upon any person, firm, or corporation, other than the Company, its officers and directors, and each Purchaser’s own advisors, in making its investment
or decision to invest in the Company. 
 (k) Counterparts; Facsimiles. This Agreement may be executed in two or
more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. A facsimile, telecopy or other reproduction of this Agreement may be executed by one or more Parties and delivered
by such Party by facsimile or any similar electronic transmission device pursuant to which the signature of or on behalf of such Party can be seen. Such execution and delivery shall be considered valid, binding and effective for all purposes. At the
request of any Party, all Parties severally agree to execute and deliver an original of this Agreement as well as any facsimile, telecopy or other reproduction hereof. 
 (l) Titles and Subtitles. The titles and subtitles used in this Agreement are used for convenience only and are not to be considered in construing or interpreting this Agreement. 

  
 -19-

 (m) Delays or Omissions. No delay or omission to exercise any right, power or
remedy accruing to any Party under this Agreement, upon any breach or default of any other Party under this Agreement, shall impair any such right, power or remedy of such non-breaching or non-defaulting Party nor shall it be construed to be a
waiver of any such breach or default, or an acquiescence therein, or of or in any similar breach or default thereafter occurring; nor shall any waiver of any single breach or default be deemed a waiver of any other breach or default theretofore or
thereafter occurring. Any waiver, permit, consent or approval of any kind or character on the part of any Party of any breach or default under this Agreement, or any waiver on the part of any Party of any provisions or conditions of this Agreement,
must be in writing and shall be effective only to the extent specifically set forth in such writing. All remedies, either under this Agreement or by law otherwise affording to any Party, shall be cumulative and not alternative. 

(n) Severability. If one or more provisions of this Agreement are held to be unenforceable under applicable law, the
Parties agree to renegotiate such provision in good faith. In the event that the Parties cannot reach a mutually agreeable and enforceable replacement for such provision, then (i) such provision shall be excluded from this Agreement,
(ii) the balance of the Agreement shall be interpreted as if such provision were so excluded and (iii) the balance of the Agreement shall be enforceable in accordance with its terms. 

(o) Entire Agreement. This Agreement, and the documents referred to herein constitute the entire agreement between the
Parties to the subject matter hereof, and any and all other written or oral agreements relating to the subject matter hereof existing between the Parties are expressly canceled. 

[Remainder of Page Intentionally Left Blank] 

  
 -20-

 IN WITNESS WHEREOF, the Parties have executed this Agreement as of the date first above
written. 
  

	
	COMPANY
	
	 SAGENT HOLDING CO.,
 a
Cayman Islands exempted company

	
	 /s/ Jeffrey Yordon

	Jeffrey Yordon
	President and CEO

  

SIGNATURE PAGE TO SAGENT HOLDING CO.

 SERIES A PREFERENCE SHARES PURCHASE AGREEMENT

 IN WITNESS WHEREOF, the Parties have executed this Agreement as of the date first above
written. 
  

	
	PURCHASERS:
	
	DOHMEN INVESTMENT GROUP, LLC
	
	By: /s/ Cynthia
LaConte                                        
    
	(signature)
	
	Name: Cynthia LaConte
	Title:   President
	
	CNF INVESTMENTS II, LLC
	
	By: /s/ Robert J.
Flanagan                                        
  
	(signature)
	
	Name: Robert J. Flanagan
	Title: Manager

  

SIGNATURE PAGE TO SAGENT HOLDING CO.

 SERIES A PREFERENCE SHARES PURCHASE AGREEMENT

 IN WITNESS WHEREOF, the Parties have executed this Agreement as of the date first above
written. 
  

	
	PURCHASERS:
	
	VIVO VENTURES FUND CAYMAN V, L.P.
	
	By: Vivo Ventures Cayman V (GP), L.P.
	
	By: Vivo Ventures Cayman V General Partner Limited, its general partner
	
	 By: /s/ Frank
Kung                                         
           

	(signature)
	
	Name: Frank
Kung                                         
           
	(print name)
	
	Title: Director
	
	VIVO VENTURES V AFFILIATES FUND, L.P.
	
	By: /s/ Frank
Kung                                         
           
	(signature)
	
	Name: Frank Kung
	 Title: Managing Member of Vivo Ventures V, LLC,
 its general partner

  

SIGNATURE PAGE TO SAGENT HOLDING CO.

 SERIES A PREFERENCE SHARES PURCHASE AGREEMENT

 IN WITNESS WHEREOF, the Parties have executed this Agreement as of the date first above
written. 
  

	
	PURCHASERS:
	
	VIVO VENTURES VI AFFILIATES FUND L.P.
	By: Vivo Ventures VI, LLC, its general partner
	
	By: /s/ Frank
Kung                                         
           
	(signature)
	
	Name: Frank Kung
	Title: Managing Member
	
	VIVO VENTURES FUND CAYMAN VI, L.P.
	By:  Vivo Venture Cayman VI (GP), L.P.
	 By:  Vivo Ventures Cayman VI General Partner
         Limited, its general partner

	
	By: /s/ Frank
Kung                                         
           
	(signature)
	
	Name: Frank Kung
	Title: Director

SIGNATURE PAGE TO SAGENT HOLDING CO.

 SERIES A PREFERENCE SHARES PURCHASE AGREEMENT

 IN WITNESS WHEREOF, the Parties have executed this Agreement as of the date first above
written. 
  

	
	PURCHASERS:
	
	 STORMLAUNCH & CO. FOR THE BENEFIT OF MORGAN STANLEY PRIVATE MARKETS

FUND III LP

	
	 By: Morgan Stanley Alternative Investment
 Partners LP, its general partner

	By: Morgan Stanley AIP GP LP, its general partner
	 By: Morgan Stanley Alternative Investments Inc.,
 its general partner

	
	By: /s/ James
Sperans                                        
            
	Name: James Sperans
	Title: Executive Director
	
	 STORMSTAR & CO. FOR THE BENEFIT OF
 MORGAN STANLEY PRIVATE MARKETS
 FUND EMPLOYEE INVESTORS III LP

	
	 By: Morgan Stanley Alternative Investment
 Partners LP, its general partner

	By: Morgan Stanley AIP GP LP, its general partner
	 By: Morgan Stanley Alternative Investments Inc.,
 its general partner

	
	By: /s/ James
Sperans                                        
            
	Name: James Sperans
	Title: Executive Director

SIGNATURE PAGE TO SAGENT HOLDING CO.

 SERIES A PREFERENCE SHARES PURCHASE AGREEMENT

 IN WITNESS WHEREOF, the Parties have executed this Agreement as of the date first above
written. 
  

	
	PURCHASERS:
	
	FACTORY MUTUAL INSURANCE COMPANY
	
	By: /s/ Paul
LaFleche                                        
        
	Name: Paul LaFleche
	Title: Senior Vice President of Investments
	
	NUCLEAR ELECTRIC INSURANCE LIMITED
	
	 By: Morgan Stanley Investment Management Inc.,
 its investment manager

	
	By: /s/ James
Sperans                                        
        
	Name: James Sperans
	Title: Executive Director

SIGNATURE PAGE TO SAGENT HOLDING CO.

 SERIES A PREFERENCE SHARES PURCHASE AGREEMENT

 Schedule A 

Schedule of Exceptions 

  

SIGNATURE PAGE TO SAGENT HOLDING CO.

 SERIES A PREFERENCE SHARES PURCHASE AGREEMENT

 Exhibit A-1 

Schedule of Purchasers 
  

																					
	FIRST CLOSING	  
	 Name and Address of
 Purchaser
	  	ERISA
Purchaser	 	  	Number of
Shares	 	  	Aggregate
Purchase 
Price	 	  	Purchase
Amount in Cash	 	  	Purchase
Amount
in
Cancellation
of
Indebtedness
(including
interest

accrued)	 
	 Dohmen Investment Group, LLC

 
 215 North Water Street, Suite 300 Milwaukee,
WI 53202
 Attn: Daniel J. Jagla
	  				  	 	5,000,000	  	  	$	5,000,000	  	  	$	5,000,000	  	  			
						
	 CNF Investments II, LLC

 
 7500 Old Georgetown Road

Bethesda, MD 20814

Attn: Robert J. Flanagan, Manager
	  				  	 	5,000,000	  	  	$	5,000,000	  	  	$	5,000,000	  	  			
						
	 Vivo Ventures Fund Cayman V, L.P.

 
 c/o Vivo Ventures V, LLC

575 High Street, Suite 201

Palo Alto, CA 94301

Attn: Chen Yu
	  				  	 	1,853,250	  	  	$	1,853,250	  	  	$	1,853,250	  	  			
						
	 Vivo Ventures V Affiliates Fund, L.P.

 
 c/o Vivo Ventures V, LLC

575 High Street, Suite 201

Palo Alto, CA 94301

Attn: Chen Yu
	  				  	 	21,750	  	  	$	21,750	  	  	$	21,750	  	  			
						
	 Vivo Ventures VI Affiliates Fund, L.P.

 
 575 High Street, Suite 201

Palo Alto, CA 94301

Attn: Chen Yu
	  				  	 	22,727	  	  	$	22,727	  	  	$	22,727	  	  			

  

																			
	FIRST CLOSING	  
	 Name and Address of
 Purchaser
	  	ERISA
Purchaser	  	Number of
Shares	 	  	Aggregate
Purchase Price	 	  	Purchase
Amount 
in
Cash	 	  	Purchase
Amount
in
Cancellation
of
Indebtedness
(including
interest
accrued)	 
	 Vivo Ventures Fund Cayman VI, L.P.
  

575 High Street, Suite 201

Palo Alto, CA 94301

Attn: Chen Yu
	  		  	 	3,102,273	  	  	$	3,102,273	  	  	$	3,102,273	  	  			
						
	 Stormlaunch & Co. for the Benefit of Morgan Stanley

Private Markets Fund III LP
  

c/o Morgan Stanley Alternative Investments Inc.

One Tower Bridge
 100 Front Street, Suite 1100
 West Conshohocken,
Pennsylvania 19428-2881
 Attn.: Matthew Allen, Vice President
	  		  	 	13,000,000	  	  	$	13,000,000	  	  	$	13,000,000	  	  			
						
	 Stormstar & Co. for the Benefit of Morgan Stanley Private

Markets Fund Employee Investors III LP

 
 c/o Morgan Stanley Alternative Investments
Inc.
 One Tower Bridge

100 Front Street, Suite 1100

West Conshohocken, Pennsylvania 19428-2881

Attn.: Matthew Allen, Vice President
	  		  	 	400,000	  	  	$	400,000	  	  	$	400,000	  	  			
						
	 Factory Mutual Insurance Company

 
 225 Wyman Street

Waltham, MA 02454

Attn: Paul LaFleche
	  		  	 	800,000	  	  	$	800,000	  	  	$	800,000	  	  			

																					
	FIRST CLOSING	  
	 Name and Address of
 Purchaser
	  	ERISA
Purchaser	 	  	Number of
Shares	 	  	Aggregate
Purchase Price	 	  	Purchase
Amount in Cash	 	  	Purchase
Amount
in
Cancellation
of
Indebtedness
(including
interest

accrued)	 
	 Nuclear Electric Insurance Limited
  

1201 North Market Street, 11th Floor

Wilmington, DE 19801

Attn: Robert MacGovern
	  				  	 	800,000	  	  	$	800,000	  	  	$	800,000	  	  			
	 First Closing Total:
	  				  	 	30,000,000	  	  	$	30,000,000	  	  	$	30,000,000	  	  			

  

																					
	SUBSEQUENT CLOSING	  
	 Name and Address of
 Purchaser
	  	ERISA
Purchaser	 	  	Number of
Shares	 	  	Aggregate
Purchase 
Price	 	  	Purchase
Amount in Cash	 	  	Purchase
Amount in
Cancellation of
Indebtedness	 
						
	 Subsequent Closing Total:
	  				  				  				  				  			

 Exhibit A-2 

Regulation S Investors 
 [none]

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