Document:

exv4w6

 

Exhibit 4.6

OCULUS INNOVATIVE SCIENCES, INC.

AMENDED AND RESTATED

INVESTORS RIGHTS AGREEMENT

          THIS AMENDED AND RESTATED INVESTORS RIGHTS AGREEMENT (this “Agreement”) is made and
entered into effective as of the date set forth in Section 28 hereof, by and among (i) Oculus
Innovative Sciences, Inc., a California corporation (the “Company”), (ii) those parties
(each an “Existing Investor” and collectively the “Existing Investors”) listed on
Schedule A attached to that certain Series A Preferred Shares Investors’ Rights Agreement
previously entered into by and among such Existing Investors and the Company (the “Prior
Agreement”), (iii) those parties as set forth in Schedule A attached hereto (each a
“New Investor” and collectively the “New Investors”), and (iv) the individuals as
set forth in Schedule B attached hereto (each a “Principal Shareholder” and
collectively the “Principal Shareholders”). The Existing Investors and the New Investors
are referred to herein collectively as the “Investors”.

RECITALS

     WHEREAS, the Company and the Existing Investors have previously entered into the Prior
Agreement providing certain registration and other rights to the Existing Investors.

     WHEREAS, the Company proposes to sell and issue to certain New Investors and such New
Investors desire to purchase up to an aggregate of 3,500,000 shares of Series B Preferred Stock of
the Company (the “Series B Preferred”), any or all of which Series B Preferred may be sold
pursuant to a Private Placement Memorandum (the “Memorandum”) and the Series B Preferred
Share Subscription Agreement attached to the Memorandum as Exhibit C (the “Subscription
Agreement”), or such other documents as the Company may deem appropriate (the “Other
Documents”) (the Memorandum, Subscription Agreement, and the Other Documents are referred to
herein collectively as the “Purchase Documents”).

     WHEREAS, the Company may sell such number of shares of the Series B Preferred as may be
necessary to accommodate the exercise of the Existing Preemptive Rights held by the Existing
Investors under the Prior Agreement.

     WHEREAS, the Company may propose to sell to certain New Investors in the future shares of one
or more series of preferred stock of the Company to be designated in the future.

     WHEREAS, The Company, the Investors, and the Principal Shareholders desire that this Agreement
amend and supersede the Prior Agreement in its entirety to govern the registration and other rights
set forth herein with respect to all Investors and Principal Shareholders.

     NOW, THEREFORE, in consideration of the mutual promises and covenants hereinafter set forth,
the parties hereto agree as follows:

     1. Certain Definitions. As used in this Agreement, the following terms shall have the
following respective meanings:

          “Board” means the Board of Directors of the Company.

 

 

          “Change of Control” means (i) the Company’s sale of all or substantially of its
assets, (ii) any merger, consolidation or other similar transaction involving the Company, where
the shareholders of the Company immediately prior to such transaction fail to hold more than 50% of
the capital stock of the surviving entity immediately following such transaction, or (iii) any
transaction involving the transfer, directly or indirectly, of capital stock of the Company
representing 50% or more of the voting power of the Company.

          “Commission” means the Securities and Exchange Commission or any successor agency.

          “Common Shares” means the Common Stock of the Company.

          “Exchange Act” means the Securities Exchange Act of 1934, as amended.

          “Existing Preemptive Rights” means the preemptive rights held by the Existing
Investors under Section 16 of the Prior Agreement.

          “Holder” means any person owning of record outstanding Registrable Securities which
have not been sold to the public, or any assignee thereof in accordance with Sections 7 and 13
hereof. In addition, for purposes of Sections 2 through 12 hereof, the term “Holder” shall
also include the Managing Dealer and the parties to whom the rights of the Managing Dealer under
the Managing Dealer Warrants were transferred in accordance with Section 1.3 of each applicable
Managing Dealer Warrant.

          “Initial Public Offering” means an initial public offering of securities of the
Company pursuant to a registration statement filed and declared effective under the Securities Act,
upon completion of which the Company has a class of stock that is registered under the Exchange Act
and is listed or quoted on an exchange or quotation system.

          “Major Shareholder” means any shareholder, as of the applicable date, who is an
officer or director of the Company, or holder of more than 4.9% of the Company’s capital stock on a
fully-diluted basis as calculated by dividing (1) the number of Common Shares and Preferred Shares
held by such holder by (2) the sum of (i) the number of Common Shares outstanding at the applicable
time, plus (ii) the number of Common Shares into which any Preferred Shares outstanding at the
applicable time may be converted at the applicable conversion price then in effect, plus (iii) the
number of Common Shares and Preferred Shares for which any options to purchase, rights to
subscribe, warrants or other derivative equity securities are outstanding or authorized by any duly
adopted stock option plan or other plan of the Company at the applicable time, plus (iv) the number
of Common Shares into which any other convertible or exchangeable securities, including convertible
debt securities, outstanding at the applicable time may be converted or exchanged; provided,
however, that the term “Major Shareholder” shall not include any Holder.

          “Managing Dealer” means Brookstreet Securities Corporation, a California corporation.

          “Managing Dealer Warrants” means those certain warrants issued, as of the applicable
date, to the Managing Dealer pursuant to that certain Managing Dealer Agreement

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entered into
effective April 19, 2004 by and between the Company and the Managing Dealer, as may be subsequently
amended from time to time.

          “Parties” means the parties that are signatories of this Agreement or hereafter agree
in writing to be bound by this Agreement; “Party” shall refer to any one of the Parties.

          “Permitted Transfers” means (i) any sale or transfer by a Principal Shareholder of
less than 10% of the Shares such Principal Shareholder then owned in a single transaction or series
of related transactions, (ii) any transfer to another Holder, or (iii) any transfer of the Shares
to a Principal Shareholder’s ancestors, descendants or spouse, brother or sister of the Principal
Shareholder, the adopted child or adopted grandchild of the Principal Shareholder, or to a trust or
trusts for the benefit of such Principal Shareholder or such Principal Shareholder’s family members
as described above, or transfers by a Principal Shareholder by devise or descent, in all cases for
estate planning purposes.

          “Preferred Shares” means the Series A Preferred Stock and Series B Preferred Stock of
the Company, as well as any one or more series of the Preferred Stock of the Company to be
designated as of a future date.

          “Principal Shareholders” means the individuals identified in Schedule B
attached hereto, who are, as of the date of this Agreement, Major Shareholders.

          “Registrable Securities” means (i) Common Shares issued or issuable upon the
conversion of the Preferred Shares; and (ii) any other Common Shares issued as (or issuable upon
conversion or exercise of any warrant, right or other security which is issued as) a dividend or
other distribution with respect to or in exchange for or replacement of the Preferred Shares. In
addition, for purposes of Sections 2 through 12 hereof, the term “Registrable Securities”
shall also include Common Shares issued or issuable upon the exercise of the Managing Dealer
Warrants. Notwithstanding the foregoing, the term “Registrable Securities” shall not
include any securities (i) sold by a person to the public either pursuant to a registration
statement or Rule 144, or (ii) sold in a private transaction in which the transferor’s rights under
Section 2 or Section 3 of this Agreement are not assigned.

          The terms “register,” “registered” and “registration” refer to a
registration effected by preparing and filing a registration statement in compliance with the
Securities Act, and the declaration or ordering of the effectiveness of such registration
statement.

          “Registration Expenses” means all reasonable out-of-pocket expenses incurred by the
Company in complying with Sections 2 and 3 hereof, including, without limitation, all registration,
qualification and filing fees, printing expenses, escrow fees, fees and disbursements of counsel
for the Company, blue sky fees and expenses, accounting fees of the Company, and the reasonable
fees and expenses of one special counsel, if any, for the selling Holders, not to exceed $25,000.

          “Restricted Securities” has the meaning set forth in Section 12 hereof.

          “Securities Act” means the Securities Act of 1933, as amended.

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          “Selling Expenses” means all underwriting discounts, selling commissions and share
transfer taxes applicable to the securities registered by the Holders pursuant to this Agreement
inclusive of all fees and disbursements of counsel for any Holder (excluding amounts specified
under the definition for Registration Expenses).

          “Series A Preferred” means the Series A Preferred Stock of the Company.

          “Series B Director” means the director on the Board for whom the holders of Series B
Preferred have a right to elect under the Company’s Articles of Incorporation.

          “Series B Holder” means the holder of any Series B Preferred.

          “Series B Preferred” means the Series B Preferred Stock of the Company.

          “Shares” has the meaning set forth in Section 9 hereof.

     2. Piggyback Registration Rights.

          2.1 Obligation to Register. If the Company determines, in its discretion, to register
any of its securities under the Securities Act in connection with the public offering of such
securities for cash, either for its own account or the account of a security holder on a form in
which the Registrable Securities may be included, other than (i) a registration relating to
employee stock option, stock purchase or other benefit plans, (ii) a registration relating to Rule
145 of the Securities Act or similar transaction, or (iii) a registration on any form that does not
include substantially the same information as could be required to be included in a registration
statement covering the sale of Registrable Securities, the Company will (i) promptly give to each
Holder written notice thereof; and (ii) include in such registration (and any related qualification
under blue sky laws or other compliance), and in any underwriting involved therein, all the
Registrable Securities specified in a written request or requests, made within twenty (20) days
after mailing of written notice by the Company, by any Holder, except as set forth in Section 2.2
below.

          2.2 Underwriting. If the registration is for a registered public offering involving
an underwriting, the Company shall so advise the Holders as part of the written notice given
pursuant to Section 2.1 above and the right of any Holder to registration pursuant to this Section
2 shall be conditioned upon such Holder’s participation in such underwriting and the inclusion of
such Holder’s Registrable Securities in the underwriting to the extent provided herein. All
Holders proposing to distribute their securities through such underwriting shall (together with the
Company and other holders distributing their securities through such underwriting) enter into an
underwriting agreement in customary form with the underwriter or underwriters selected for such
underwriting by the Company. Notwithstanding any other provision of this Section 2, if the
managing underwriter advises the Company in writing that in its opinion pricing or marketing
factors make advisable a limitation of the number of shares to be underwritten, then (i) in the
Company’s Initial Public Offering of Common Shares, the managing underwriter may exclude all
Registrable Securities from such registration involving an underwriting; and (ii) in a registered
public offering and underwriting not involving an Initial Public Offering, limit the number of
Registrable Securities to be included in the registration and underwriting by reducing the number
of Registrable Securities included on behalf of the Holders on a pro rata basis based on the total
number of Registrable Securities entitled to registration held

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by each Holder; provided, however,
that no Registrable Securities shall be excluded from a registration under this clause (ii) until
all other outstanding securities of the Company held by the Major Shareholders shall have first
been excluded from such registration and underwriting and provided further that in no event may the
number of Registrable Securities to be included in a registration and underwriting other than the
Company’s Initial Public Offering of Common Shares be reduced to less than 30% of the total number
of shares to be included in such registration and underwriting. The Company shall advise all
Holders of Registrable Securities which would otherwise be registered and underwritten pursuant
hereto of any such limitations.

     3. Demand Registration. If, at any time after six months following the Company’s
Initial Public Offering of Common Shares, the Holders holding at least 50% of the total Registrable
Securities (“Initiating Holders”) request in writing that the Company file a registration
statement on a form in which the Registrable Securities may be included, the Company shall (i)
promptly give written notice of the proposed registration to all other Holders; and (ii) cause all
or such portion of such Registrable Securities as are specified in such request in writing received
by the Company within thirty (30) days after mailing of such written notice from the Company to be
registered on such form (or any successor thereto). Notwithstanding the foregoing, if the Board
determines that such a filing would not be in the best interest of the Company at the time of the
request, the Company may delay the filing of a registration statement requested pursuant to this
Section 3 for a period (a “Company Delay Period”) not in excess of 120 days, which right
may not be exercised more than twice in any 12-month period provided that in the aggregate any and
all Company Delay Periods shall not exceed 120 days. The Company shall be required to file no more
than one registration statement pursuant to this Section 3. The Company may elect to use Form S-3
(or any successor thereto) to satisfy any registration pursuant to this Section 3 if such form is
available.

     4. Expenses of Registration. All Registration Expenses incurred in connection with
any registration, qualification or compliance pursuant to Section 2 and Registration Expenses of up
to one registration pursuant to Section 3 shall be borne by the Company, provided, however, that
the Company shall not be required to pay for any expenses of any registration proceeding begun
pursuant to such Section 3 if the registration request is subsequently withdrawn at the request of
the Holder(s) that requested such registration or the Holders of a majority of the Registrable
Securities to be registered (in which case such Holders shall bear such expenses). All Selling
Expenses relating to securities registered by the Holders shall be borne by the Holders of such
securities.

     5. Registration Procedures. In the case of each registration, qualification or
compliance effected by the Company with respect to Registrable Securities pursuant to this
Agreement, the Company will keep each Holder advised in writing as to the initiation of each
registration, qualification or compliance and as to the completion thereof, and, at the Company’s
expense, will:

          5.1 Effectiveness. Prepare and file with the Commission a registration statement with
respect to such Registrable Securities and use its commercially reasonable best efforts to cause
such registration statement to become and remain effective for at least 90 days or until the
distribution described in the registration statement has been completed, whichever is shorter;
provided, however, that such 90 day period shall be extended (i) to the extent required by Section
5.7, and (ii) for a period of time equal to any period the Holder refrains from selling any

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securities during the effectiveness of such registration at the request of an underwriter or the
Company pursuant to Section 9;

          5.2 Amendments. Prepare and file with the Commission such amendments and supplements
to such registration statement and the prospectus used in connection with such registration
statement as may be necessary to comply with the provisions of the Securities Act with respect to
the disposition of all securities covered by such registration statement;

          5.3 Copies of Documents. Furnish to the Holders participating in such registration
and to the underwriters of the securities being registered such reasonable number of copies of the
registration statement, preliminary prospectus, final prospectus and such other documents as such
underwriters or such Holders may reasonably request in order to facilitate the public offering of
such Registrable Securities;

          5.4 Blue Sky Laws. Use its commercially reasonable best efforts to register and
qualify the Registrable Securities covered by such registration statement under such other
securities or blue sky laws of such jurisdictions as shall be reasonably requested by the Holders;
provided that the Company shall not be required in connection therewith or as a condition thereto
to qualify to do business or to file a general consent to service of process in any such states or
jurisdictions, unless the Company is already subject to service in such jurisdiction and except as
may be required by the Securities Act;

          5.5 Underwriting Agreement. In the event of any underwritten public offering, enter
into and perform its obligations under an underwriting agreement, in usual and customary form, with
the managing underwriter of such offering; provided that each Holder participating in such
underwriting shall also enter into and perform its obligations under such underwriting agreement;

          5.6 Notification. Notify each Holder of Registrable Securities covered by such
registration statement if at any time the Company shall determine that the registration statement
or any prospectus included therein shall contain an untrue statement of material fact or omit a
material fact necessary to make the statements therein, in the light of the circumstances in which
they were made, not misleading, and thereafter, subject to Section 5.7 and the last paragraph of
this Section 5, promptly prepare and file with the Commission an amendment to the registration
statement or a supplement to the prospectus as may be necessary to correct such untrue statement or
omission, and notify the selling Holders of such filing;

          5.7 Amendment or Supplement to Registration Statement. In the event that, at any time
when a prospectus relating to such Registrable Securities is required to be delivered under the
Securities Act, the Company determines that any event shall have occurred as the result of which
any such prospectus or any other prospectus then in effect would include an untrue statement of a
material fact or omit a material fact necessary to make the statements therein, in light of the
circumstances in which they were made, not misleading or if the Company determines that an
amendment to the registration statement or supplement to the prospectus is advisable before further
sales of Registrable Securities should be made, prepare and file as soon as reasonable with the
Commission such amendment to the registration statement or supplement to the prospectus and
promptly notify each Holder of Registrable Securities covered by such registration statement of the
filing of such amendment or supplement to the registration statement or prospectus as may be
necessary to correct any statements or omissions; provided

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that if the Board of Directors of the
Company determines that amending the registration statement or supplementing the prospectus might
be detrimental to the Company, then, notwithstanding this Section 5.7, the Company may defer such
amendment or supplement for up to 120 days, provided that: (i) the Company shall not use such right
of deferral with respect to any registration statement for more than an aggregate of 120 days in
any 12-month period; and (ii) the number of days the Company is required to keep the registration
statement effective shall be extended by the number of days for which the Company shall have used
such right of deferral;

          5.8 Stop Order. Advise each Holder of Registrable Securities covered by such
registration statement promptly after it shall receive notice or obtain knowledge thereof, of the
issuance of any stop order by the Commission suspending the effectiveness of the Registration
Statement or the initiation or threatening of any proceeding for that purpose and promptly use its
commercially reasonable best efforts to prevent the issuance of any stop order or to obtain its
withdrawal if such stop order should be issued;

          5.9 Listing. Cause such Registrable Securities registered hereunder to be listed on
each securities exchange or quoted on a quotation system on which similar securities issued by the
Company are then listed; and

          5.10 Transfer Agent and Registrar. Provide a transfer agent and registrar for all
Registrable Securities registered hereunder and a CUSIP number for all such Registrable Securities,
in each case not later than the effective date of such registration.

     If a Holder receives a notification from the Company pursuant to this Section 5 that a
registration statement or prospectus contains an untrue statement or omission or that the Company
is exercising its rights pursuant to Section 5.7, then such Holder shall: (i) keep the fact of such
notification and its contents confidential, and (ii) immediately suspend all sales of securities of
the Company and any use of the registration statement or prospectus as to which the notification
applies, until such time as such Holder receives notification from the Company that an amendment to
the registration statement or a supplement to the prospectus has been filed and that sales may be
made.

     6. Termination of Registration Rights. Except as provided elsewhere in this
Agreement, the registration rights granted pursuant to this Agreement shall terminate on the first
to occur of the following: (i) as to all Holders, on the second anniversary of the closing of the
Initial Public Offering, and (ii) as to any Holder, at anytime after the Initial Public Offering
that such Holder holds less than 1% of the total outstanding Common Shares of the Company, or (iii)
as to any Holder, at such time as such Holder is eligible to sell all Registrable Securities held
by it pursuant to Rule 144 promulgated under the Securities Act. 

     7. Transfer of Registration Rights. The rights granted hereunder to cause the Company
to register securities or to participate in a registration of the Company may not be assigned to
any transferee or assignee of Restricted Securities unless the transferee agrees to be bound by the
terms and conditions of this Agreement and the Company receives written notice within twenty (20)
days after such transfer.

     8. Indemnification.

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          8.1 Company Indemnification. The Company will indemnify each Holder, each of its
officers, directors and partners, and each person controlling such Holder within the meaning of
Section 15 of the Securities Act, with respect to which registration, qualification or compliance
has been effected pursuant to this Agreement, and each underwriter, if any, and each person who
controls any underwriter within the meaning of Section 15 of the Securities Act, against all
expenses, claims, losses, damages and liabilities (or actions in respect thereof), including any of
the foregoing incurred in settlement of any litigation, arising out of or based on any untrue
statement (or alleged untrue statement) of a material fact contained in any registration statement,
prospectus, offering circular or other document, or any amendment or supplement thereto, incident
to any such registration, qualification or compliance, or based on any omission (or alleged
omission) to state therein a material fact required to be stated therein or necessary to make the
statements therein not misleading, or any violation by the Company of any rule or regulation
promulgated under the Securities Act applicable to the Company and relating to action or inaction
required of the Company in connection with any such registration, qualification or compliance, and
will reimburse each such Holder, each of its officers, directors and partners, and each person
controlling such Holder, each such underwriter and each person who controls any such underwriter,
for any legal and any other expenses reasonably incurred in connection with investigating,
preparing or defending any such claim, loss, damage, liability or action, provided the Company
shall not be liable for amounts paid in settlement of any claims if such settlement is made without
the consent of the Company, which consent shall not be unreasonably withheld, and that the Company
will not be liable in any such case to the extent that any such claim, loss, damage, liability or
expense arises out of or is based on any untrue statement or omission or alleged untrue statement
or omission, made in reliance upon and in conformity with written information furnished to the
Company by a Holder or underwriter specifically for use therein.

          8.2 Holder Indemnification. Each Holder will, if Registrable Securities held by such
Holder are included in the securities as to which registration, qualification or compliance has
been effected pursuant to this Agreement, indemnify the Company, each of its directors and
officers, each underwriter, if any, of the Company’s securities covered by such a registration
statement, each person who controls the Company or such underwriter within the meaning of Section
15 of the Securities Act, and each other such Holder, each of its officers and directors and each
person controlling such Holder within the meaning of Section 15 of the Securities Act, against all
claims, losses, damages and liabilities (or actions in respect thereof) arising out of or based on
any untrue statement (or alleged untrue statement) of a material fact contained in any such
registration statement, prospectus, offering circular or other document, or any omission (or
alleged omission) to state therein a material fact required to be stated therein or necessary to
make the statements therein not misleading, and will reimburse the Company, such Holders, such
directors, officers, underwriters or control persons for any legal or any other expenses reasonably
incurred in connection with investigating or defending any such claim, loss, damage, liability or
action, in each case to the extent, but only to the extent, that such untrue statement (or alleged
untrue statement) or omission (or alleged omission) is made in such registration statement,
prospectus, offering circular or other document in reliance upon and in conformity with written
information furnished to the Company by or on behalf of such Holder and stated to be specifically
for use therein; provided, however, that the obligations of any such Holder hereunder shall be
limited to an amount equal to the gross proceeds before expenses and commissions to such Holder of
Registrable Securities sold as contemplated herein.

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          8.3 Notification of Claim. Each party entitled to indemnification under this Section
8 (the “Indemnified Party”) shall give notice to the party required to provide
indemnification (the “Indemnifying Party”) promptly after such Indemnified Party has actual
knowledge of any claim as to which indemnity may be sought, and shall permit the Indemnifying Party
to assume the defense of any such claim or any litigation resulting therefrom, provided that
counsel for the Indemnifying Party, who shall conduct the defense of such claim or litigation,
shall be approved by the Indemnified Party (whose approval shall not be unreasonably withheld), and
the Indemnified Party may participate in such defense at such party’s expense; provided, however,
that the Indemnified Party (together with all other Indemnified Parties that may be represented
without conflict by one counsel) shall have the right to retain one separate counsel, with the fees
and expenses to be paid by the Indemnifying Party, if representation of such Indemnified Party by
the counsel retained by the Indemnifying Party would be inappropriate due to differing interests
between such Indemnified Party and any other party represented by such counsel in such proceeding;
and provided further that the failure of any Indemnified Party to give notice as provided herein
shall not relieve the Indemnifying Party of its obligations under this Agreement, except to the
extent, but only to the extent, that the Indemnifying Party’s ability to defend against such claim
or litigation is impaired as a result of such failure to give notice. No Indemnifying Party, in
the defense of any such claim or litigation, shall, except with the consent of each Indemnified
Party, consent to entry of any judgment or enter into any settlement which does not include as an
unconditional term thereof the giving by the claimant or plaintiff to such Indemnified Party of a
release from all liability in respect to such claim or litigation.

          8.4 Contribution. If the indemnification provided for in Sections 8.1 and 8.2 of this
Section 8 is unavailable or insufficient to hold harmless an Indemnified Party thereunder, then
each Indemnifying Party thereunder shall contribute to the account paid or payable by such
Indemnified Party as a result of the losses, claims, damages, costs, expenses, liabilities or
actions referred to in Sections 8.1 and 8.2 in such proportion as is appropriate to reflect the
relative fault of the Indemnifying Party on the one hand and the Indemnified Party on the other in
connection with statements or omissions which resulted in such losses, claims, damages or
liabilities, as well as any other relevant equitable considerations. The relative fault shall be
determined by a court of law by reference to, among other things, whether the untrue or alleged
untrue statement of a material fact or the omission or alleged omission to state a material fact
relates to information supplied by the Indemnifying Party or the Indemnified Party and the parties’
relative intent, knowledge, access to information and opportunity to correct or prevent such untrue
statements or omissions. The parties hereto agree that it would not be just and equitable if
contributions pursuant to this Section 8.4 were to be determined by pro rata or per capita
allocation or by any other method of allocation which does not take account of the equitable
considerations referred to in the first sentence of this Section 8.4. The amount paid by an
Indemnified Party as a result of the losses, claims, damages or liabilities referred to in the
first sentence of this Section 8.4 shall be deemed to include any legal or other expenses
reasonably incurred by such Indemnified Party in connection with investigating or defending any
action or claim which is the subject of this Section 8.4. Promptly after receipt by an Indemnified
Party of notice of the commencement of any action against such party in respect of which a claim
for contribution may be made against an Indemnifying Party under Section 8.4, such Indemnified
Party shall notify the Indemnifying Party in writing of the commencement thereof if the notice
specified in Section 8.3 has not been given with respect to such action; provided that the omission
so to notify the Indemnifying Party shall not relieve the Indemnifying Party from any liability
which it may have to any Indemnified Party otherwise under Section 8.4, except to the extent that
the Indemnifying Party is actually

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prejudiced by such failure to give notice. The parties hereto
agree with each other and shall agree with the underwriters of the Common Shares of the Company
pursuant to the terms hereof, if requested by such underwriters, that (i) the underwriters’ portion
of such contribution shall not exceed the underwriting discount, commission and other compensation,
and (ii) the amount of such contribution shall not exceed an amount equal to the proceeds received
by such Indemnifying Party from the sale of securities in the offering to which the losses, claims,
damages or liabilities of the indemnified parties relate. No person guilty of fraudulent
misrepresentation (within the meaning of Section 11(f) of the Securities Act) shall be entitled to
contribution from any person who was not guilty of such fraudulent misrepresentation.

     9. Lock-up Agreement. In consideration for the Company agreeing to its obligations
under this Agreement, each Holder severally hereby agrees that such Holder shall not, to the extent
requested by the managing underwriter of a public offering in which Shares (as defined below) are
sold, directly or indirectly, offer, sell, pledge, contract to sell, transfer the economic risk of
ownership in, make any short sale, grant any option to purchase or otherwise dispose of any
Registrable Securities or any securities convertible into or exchangeable or exercisable for or any
other rights to purchase or acquire Registrable Securities, including, without limitation, Common
Shares which may be deemed to be beneficially owned by the Holders in accordance with the rules and
regulations of the Commission and Common Shares which may be issued upon exercise of a stock option
or warrant, or enter into any Hedging Transaction (as defined below) relating to Registrable
Securities (each of the foregoing referred to as a “Disposition”) for a period of 180 days
after the effective date of the registration statement relating to such public offering (the
“Lock-Up Period”) unless the managing underwriter otherwise agrees; provided, however, that
all officers and directors of the Company enter into similar agreements. The foregoing restriction
is expressly intended to preclude any Holder from engaging in any Hedging Transaction or other
transaction which is designed to or reasonably expected to lead to or result in a Disposition
during the Lock-Up Period even if the securities would be disposed of by someone other than such
Holder. “Hedging Transaction” means any short sale (whether or not against the box) or any
purchase, sale or grant of any right (including, without limitation, any put or call option) with
respect to any security (other than a broad-based market basket or index) that includes, relates to
or derives any significant part of its value from the Shares. “Shares” shall mean equity
securities of the Company that are, or that are convertible directly or indirectly into, Common
Shares. Each Holder agrees that the Company may instruct its transfer agent to place stop transfer
notations in its records to enforce the provisions of this Section 9.

     10. Information by Holder. The Holder or Holders of Registrable Securities included
in any registration shall furnish to the Company such information regarding such Holder or Holders
and the distribution proposed by such Holder or Holders as the Company may request in writing and
as shall be required in connection with any registration, qualification or compliance referred to
in this Agreement.

     11. Rule 144 Reporting. With a view to making available the benefits of certain rules
and regulations of the Commission which may at any time permit the sale of the Restricted
Securities to the public without registration, after such time as a public market exists for the
Common Shares of the Company, the Company agrees to:

          11.1 Public Information. Make and keep public information available, as those terms
are understood and defined in Rule 144 under the Securities Act, at all times after 90 days

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from
the effective date of the first registration statement under the Securities Act filed by the
Company for an offering of its securities to the general public; 

          11.2 Filings with Commission. Use its commercially reasonable best efforts to file
with the Commission in a timely manner all reports and other documents required of the Company
under the Securities Act and the Exchange Act (at any time after it has become subject to such
reporting requirements); and

          11.3 Compliance Statement. Furnish to Holders of Registrable Securities forthwith
upon request, a written statement by the Company as to its compliance with the reporting
requirements of Rule 144 (at any time after 90 days after the effective date of the first
registration statement filed by the Company for an offering of its securities to the general
public), and of the Securities Act and the Exchange Act (at any time after it has become subject to
such reporting requirements), a copy of the most recent annual or quarterly report of the Company,
and such other reports and documents of the Company as a Holder of Registrable Securities may
reasonably request in availing itself of any rule or regulation of the Commission allowing such
Holder to sell any such securities without registration.

     12. Restrictive Legend. Each certificate representing (i) Common Shares, (ii)
Preferred Shares, (iii) Common Shares issued upon conversion of the Preferred Shares, and (iv) any
other securities issued in respect of the Preferred Shares and Common Shares issued upon conversion
of the Preferred Shares (any such securities listed in the preceding subsections (i), (ii), (iii)
or (iv), “Restricted Securities”), shall (unless otherwise permitted by the provisions of
Section 13 below) be stamped or otherwise imprinted with a legend substantially in the following
form (in addition to any legend required under applicable state securities laws):

THESE SECURITIES HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS
AMENDED. THEY MAY NOT BE SOLD, OFFERED FOR SALE, PLEDGED, HYPOTHECATED OR OTHERWISE
TRANSFERRED EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION UNDER THE SECURITIES ACT OF
1933, OR AN OPINION OF COUNSEL SATISFACTORY TO THE COMPANY THAT SUCH REGISTRATION IS
NOT REQUIRED. THE SHARES REPRESENTED BY THIS CERTIFICATE ARE SUBJECT TO AN
AGREEMENT RESTRICTING THEIR TRANSFER, A COPY OF WHICH IS ON FILE AT THE OFFICE OF
THE COMPANY AND WILL BE FURNISHED TO ANY PROSPECTIVE PURCHASERS ON REQUEST. THE
AGREEMENT PROVIDES, AMONG OTHER THINGS, FOR CERTAIN RESTRICTIONS ON THE SALE,
TRANSFER, PLEDGE, HYPOTHECATION OR OTHER DISPOSITION OF THE SHARES REPRESENTED BY
THIS CERTIFICATE.

     13. Restrictions on Transferability. Each Investor who holds certificate(s)
representing Restricted Securities, by acceptance thereof, agrees to comply in all respects with
the provisions of this Section 13. Prior to any proposed transfer of any Restricted Securities by
an Investor, unless there is in effect a registration statement under the Securities Act covering
the proposed transfer, such Investor shall give written notice to the Company of such Investor’s
intention to effect such transfer. Each such notice shall describe the manner and circumstances of
the proposed transfer in sufficient detail, and shall, if the Company so requests, be

11

 

accompanied
(except in transactions in compliance with Rule 144) by an unqualified written opinion of legal
counsel (to be paid for by the Company in an amount not to exceed $500) who shall be reasonably
satisfactory to the Company, addressed to the Company and reasonably satisfactory in form and
substance to the Company’s counsel, to the effect that the proposed transfer of the Restricted
Securities may be effected without registration under the Securities Act or applicable blue sky
laws. Each Investor shall cause any proposed transferee of the Registrable Securities held by such
Investor to agree to take and hold such securities subject to the provisions specified in this
Section 13 and Section 9 hereof. Each certificate evidencing the Restricted Securities transferred
as above provided shall bear the appropriate restrictive legend set forth in Section 12 above,
except that such certificate shall not bear such restrictive legend if in the opinion of counsel
for the Company such legend is not required in order to establish compliance with any provisions of
the Securities Act.

     14. Information Rights. The Company shall furnish to any Investor, (i) within 90 days
after the end of each fiscal year, unaudited annual financial reports, or audited financial
statements if they are available, (ii) within 45 days after the end of each quarter, quarterly
management reports, and (iii) at least 30 days prior to the end of each fiscal year, an annual
budget. The Company shall also make its officers available to any Investor upon reasonable notice
to answer questions and shall make its financial records available to any Investor upon reasonable
notice. The information rights set forth in this Section 14 shall expire upon the earlier of: (i)
the closing date of the Initial Public Offering, (ii) the time the Company becomes a reporting
company under the Exchange Act, or (iii) a Change of Control.

     15. Co-Sale Rights.

          15.1 Notice of Proposed Transfer. Before a Principal Shareholder may effect any
transfer of any Common Shares owned by such Principal Shareholder (the “Offered Shares”)
other than pursuant to a Permitted Transfer, such Principal Shareholder (the “Selling Principal
Shareholder”) must give to the Company and to the Holders a written notice signed by the
Selling Principal Shareholder (the “Selling Principal Shareholder’s Notice”) stating (a)
the number of Offered Shares to be transferred, and (b) the bona fide cash price or, in reasonable
detail, other consideration, per share (the “Offered Price”) for which the Selling
Principal Shareholder proposes to transfer such Offered Shares.

          15.2 Rights of Co-Sale.

               (1) Each Holder will have the right to sell, on the terms and to the proposed transferee
described in the Selling Principal Shareholder’s Notice, that number of Shares equal to the product
obtained by multiplying (i) the aggregate number of Offered Shares by (ii) a fraction, the
numerator of which is the number of Shares then held by such Holder, and the denominator of which
is the total combined number of Shares then held by the Selling Principal Shareholder (including
shares transferred pursuant to Permitted Transfers by such selling Principal Shareholder in
accordance herewith) and the number of Shares issued or issuable to all Holders that desire to
exercise their co-sale rights pursuant to this Section 15. For purposes of making such
computation, the Holder shall be deemed to own the number of Shares issued or issuable upon
conversion of all its Preferred Shares. Holders may exercise such rights of co-sale by giving
written notice to the Selling Principal Shareholder within ten (10) days after the date of the
Selling Principal Shareholder’s Notice, specifying the number of Shares which the

12

 

Holder desires to
transfer to the Selling Principal Shareholder’s proposed transferee, in which case the number of
Offered Shares which the Selling Principal Shareholder may sell pursuant to the Selling Principal
Shareholder’s Notice shall be correspondingly reduced.

               (2) The Holder may effectuate its right of co-sale contemplated by this Section 15 by
delivering to the Selling Principal Shareholder for transfer to the proposed transferee one or more
certificates, properly endorsed for transfer, which represent:

                    i. the number of Common Shares which the Holder is entitled to, and elects to, sell pursuant
to this Section 15; or

                    ii. that number of Preferred Shares which is at such time convertible into the number of
Common Shares which such Holder elects to sell pursuant to this Section 15; provided, however, that
if the proposed transferee objects to the delivery of Preferred Shares in lieu of Common Shares,
the Holder may convert and deliver Common Shares as provided in subparagraph 15.2(2)(i) above.

          15.3 Deliveries. The stock certificate or certificates which a Holder delivers to a
Selling Principal Shareholder pursuant to Section 15.2 shall be transferred by such Selling
Principal Shareholder to the proposed transferee in consummation of the sale of the Shares pursuant
to the terms and conditions specified in the Selling Principal Shareholder’s Notice, and such
Selling Principal Shareholder shall promptly thereafter remit to such Holder that portion of the
sale proceeds to which such Holder is entitled by reason of its participation in such sale.

          15.4 Subsequent Sale of Shares. The exercise or non-exercise of the rights of any
Holder under this Section 15 to participate in one or more sales of the Shares made by a Selling
Principal Shareholder shall not adversely affect its right to participate in subsequent sales of
Shares by such Selling Principal Shareholder pursuant to this Section 15.

          15.5 Prohibited Transfers. In the event any Principal Shareholder should sell any
Shares in contravention of the right of co-sale set forth in this Section 15 (a “Prohibited
Transfer”), a Holder, in addition to such other remedies as may be available at law or in
equity or hereunder, shall have the put option provided Section 15.6 below, and such Principal
Shareholder shall be bound by the applicable provisions of such put option.

          15.6 Put Option. In the event of a Prohibited Transfer by a Principal Shareholder, a
Holder shall have the right (but shall not be obligated) to sell, to the Principal Shareholder who
made the Prohibited Transfer, a number of Common Shares (either directly or through conversion of
Preferred Shares) equal to the number of Shares that the Holder would have been entitled to
transfer to the proposed purchaser in the Prohibited Transfer pursuant to this Section 15, assuming
the Holder elected to exercise its co-sale rights under Section 15.2 to their fullest extent. Such
sale shall be made on the following terms and conditions:

               15.6.1 The price per share at which the Shares are to be sold to any such Principal
Shareholder shall be equal to the price per share paid by the purchaser to such Principal
Shareholder in the Prohibited Transfer. Such Principal Shareholder shall also reimburse the Holder
for any and all reasonable fees and expenses, including attorneys’ fees and expenses, incurred
pursuant to any exercise of the Holder’s rights under this Section 15.6.

13

 

               15.6.2 Within 90 days after the earlier of the dates on which the Holder (i) received notice
from such Principal Shareholder of the Prohibited Transfer, or (ii) otherwise obtained actual
knowledge of the Prohibited Transfer, the Holder shall, if exercising the put option created
hereby, deliver to such Principal Shareholder the certificate or certificates representing Shares
to be sold, each certificate to be properly endorsed for transfer. The failure of the Holder to
exercise the put option in such 90-day period shall constitute a waiver of the Holder’s right under
this Section 15.6.

               15.6.3 Such Principal Shareholder shall, upon receipt of the certificate or certificates for
the Shares to be sold by the Holder, pursuant to Section 15.6.2, pay the aggregate purchase price
therefor and the amount of fees and expenses reimbursable under Section 15.6.1, by check or wire
transfer made payable to the order of the Holder.

          15.7 Permitted Transfers. The rights of the Holders under Section 15 shall not
pertain or apply to Permitted Transfers; provided, however, that in the event of a Permitted
Transfer relating to any transfer of the Shares to a Principal Shareholder’s ancestors, descendants
or spouse, brother or sister of the Principal Shareholder, the adopted child or adopted grandchild
of the Principal Shareholder, or to a trust or trusts for the benefit of such Principal Shareholder
or such Principal Shareholder’s family members as described above, or transfers by a Principal
Shareholder by devise or descent, the Principal Shareholder shall inform the Company and the
Holders of such transfer prior to effecting it, and (2) the permitted transferee shall furnish the
Company and the Holders with a written agreement to be bound by and to comply with all provisions
of this Agreement applicable to such Principal Shareholder.

          15.8 Termination. The provisions of this Section 15 shall terminate upon the
occurrence of any one of the following events: (i) the closing of an Initial Public Offering; or
(ii) a Change of Control.

          15.9 Legends. Each certificate representing Shares now or hereafter owned by the
Principal Shareholders or issued to any permitted transferee pursuant to this Section 15 above
shall be endorsed with a legend in substantially the following form:

THE SHARES REPRESENTED BY THIS CERTIFICATE ARE SUBJECT TO CERTAIN
RIGHTS OF CO-SALE AS SET FORTH IN AN AMENDED AND RESTATED INVESTORS
RIGHTS AGREEMENT DATED [______ ___], 2004, BY AND AMONG THE
REGISTERED HOLDER, THE CORPORATION AND OTHERS. COPIES OF SUCH
AGREEMENT MAY BE OBTAINED BY THOSE PERSONS OR ENTITIES HAVING A
LEGITIMATE INTEREST UPON WRITTEN REQUEST TO THE SECRETARY OF THE
CORPORATION.

          15.10 Amendment of Co-Sale Rights. The observance of any provision of this Section 15
may be waived (either generally or in a particular instance and either retroactively or
prospectively) only with the written consent of Holders owning a majority of the Preferred Shares
(including shares issuable upon conversion of Preferred Shares) or their permitted transferees of
such rights. Any provision of this Section 15 may be amended or terminated only with the written
consent of (i) the Company; (ii) Holders owning a majority of the Preferred Shares (including
shares issuable upon conversion of Preferred Shares) or their permitted

14

 

transferees of such rights,
and (iii) the Principal Shareholders holding a majority of the shares of capital stock of the
Company then held by such Principal Shareholders.

     16. Rights of First Refusal.

          16.1 Subsequent Offerings. Each Holder shall have a right of first refusal to
purchase its pro rata share of all Equity Securities, as defined below, that the Company may, from
time to time, propose to sell and issue for cash after the date of this Agreement, other than the
Equity Securities excluded by Section 16.7 hereof; provided, however, that such Holder shall be, at
the time of the offer of such Equity Securities, an “accredited investor” as such term is defined
under Rule 501(a) promulgated under the Securities Act and shall have provided to the Company with
evidence reasonably satisfactory to the Company that such Holder is an “accredited investor.” Each
Holder’s pro rata share is equal to the ratio of (a) the number of Common Shares (including all
Common Shares issued or issuable upon conversion of the Preferred Shares) which such Holder is
deemed to be a holder immediately prior to the issuance of such Equity Securities to (b) the total
number of shares of the Company’s Fully Diluted Common immediately prior to the issuance of the
Equity Securities. The term “Equity Securities” shall mean (i) any Common Shares,
Preferred Shares or other equity security of the Company, (ii) any equity security convertible,
with or without consideration, into any Common Shares, Preferred Shares or other equity security
(including any option to purchase such a convertible security), (iii) any security carrying any
warrant or right to subscribe to or purchase any Common Shares, Preferred Shares or other equity
security or (iv) any such warrant or right. For purposes of calculating a Holder’s pro rata share
pursuant to this Section 16.1, the number of shares of the Company’s Common Shares which such
Holder is deemed to hold may, at the election of such Holder, include shares held by any entity
affiliated with such Holder, provided that, if such affiliated entity is also a Holder, such shares
shall only be counted once in such pro rata calculation, such that the shares are included for only
one such Holder. The term “Fully Diluted Common” shall mean the sum of (i) the number of
Common Shares outstanding immediately prior to such issuance, plus (ii) the number of Common Shares
into which any Preferred Shares outstanding immediately prior to such issuance may be converted at
the applicable conversion price then in effect, plus (iii) the number of Common Shares and
Preferred Shares for which any options to purchase, rights to subscribe, warrants or other
derivative equity securities are outstanding or authorized by any duly adopted stock option plan or
other plan of the Company prior to such issuance, plus (iv) the number of Common Shares into which
any other convertible or exchangeable securities, including convertible debt securities,
outstanding immediately prior to such issuance may be converted or exchanged.

          16.2 Exercise of Rights. If the Company proposes to issue any Equity Securities, it
shall give each Holder written notice (the “First Refusal Notice”) of its intention,
describing the Equity Securities, the price and the terms and conditions upon which the Company
proposes to issue the same. Each Holder shall have 15 days from the giving of such notice to agree
to purchase its pro rata share of the Equity Securities for the price and upon the terms and
conditions specified in the notice by giving written notice to the Company and stating therein the
quantity of Equity Securities to be purchased. If the Holders fail to exercise in full the rights
of first refusal, the Company shall have 90 days thereafter to sell the Equity Securities in
respect of which the Holders’ rights were not exercised, at a price and upon general terms and
conditions no more favorable to the purchasers thereof than specified in the First

15

 

Refusal Notice.
If the Company has not sold such Equity Securities within 90 days of the date of the First Refusal
Notice, the Company shall not thereafter issue or sell any Equity Securities, without first
offering such securities to the Holders in the manner provided above. Notwithstanding the
foregoing, the Company shall not be required to offer or sell such Equity Securities to any Holder
who would cause the Company to be in violation of applicable federal or state securities laws by
virtue of such offer or sale.

          16.3 Reserved.

          16.4 Sale Without Notice. In lieu of giving notice to the Holders prior to the
issuance of Equity Securities as provided in Section 16.2, the Company may elect to give notice to
the Holders within 30 days after the issuance of Equity Securities. Such notice shall describe the
type, price and terms of the Equity Securities. Each Holder shall have 30 days from the date of
receipt of such notice to elect to purchase its pro rata share of Equity Securities (as defined in
Section 16.1, and calculated by excluding such already issued Equity Securities from the Fully
Diluted Common). The closing of such sale shall occur within 60 days of the date of notice to the
Holders.

          16.5 Termination and Waiver of Rights of First Refusal. The rights of first refusal
established by this Section 16 shall terminate immediately prior to the effective date of the
registration statement pertaining to the Company’s Initial Public Offering.

          16.6 Transfer of Rights of First Refusal. The rights of first refusal of each Holder
under this Section 16 may be transferred to the same parties, subject to the same restrictions as
any transfer of registration rights pursuant to Section 7.

          16.7 Excluded Securities. The rights of first refusal established by this Section 16
shall have no application to any of the following Equity Securities:

               (1) Equity Securities issued pursuant to stock splits, stock dividends or other
recapitalization transactions;

               (2) Equity Securities issued to employees, officers, directors, consultants, contractors or
advisors of the Company pursuant to stock purchase or stock option plans or agreements or other
incentive stock arrangements approved by the Board of Directors of the Company;

               (3) Equity Securities issued to lenders, equipment lessors or other parties providing goods or
services to the Company;

               (4) Equity Securities issued in connection with acquisition transactions;

               (5) Equity Securities issued upon exercise of the Managing Dealer Warrants;

               (6) Equity Securities issued in strategic partnership transactions;

16

 

               (7) Any shares of the Series B Preferred (provided, however, that the Existing Preemptive
Rights held by holders of the Series A Preferred shall apply to the Series B Preferred); and

               (8) Equity Securities issued in any other transaction in which exemption from the right of
first refusal provisions of this Section 16 is approved by the Holders of a majority of the then
outstanding Preferred Shares.

          16.8 Waiver of Rights of First Refusal. The Existing Investors hereby waive the right
of first refusal under Section 16 of the Prior Agreement with respect to an additional 17,911
shares of Series A Preferred issued and sold by the Company in connection with the Offering (as
such term is defined under the Prior Agreement). The waiver of right of first refusal as provided
under this Section 16.8 shall not affect the Existing Preemptive Rights of the Existing Investors
with respect to the offering of the Series B Preferred.

     17. Series B Director.

          17.1 Covenants of Series B Holders. Each Investor who now holds or hereafter acquires
any shares of the Series B Preferred hereby agrees as follows:

               (1) At any time prior to the receipt by such Investor of written notice from the Company
stating that the aggregate gross proceeds resulting from the sale of the Series B Preferred
pursuant to that certain Managing Dealer Agreement dated April 19, 2004 by and between the Company
and the Managing Dealer, as may be subsequently amended from time to time (the “Managing Dealer
Agreement”), has reached an amount of no less than $3,000,000, such Investor shall not exercise
its right to elect the Series B Director as provided for in the Company’s Articles of
Incorporation;

               (2) In the event that the aggregate gross proceeds resulting from the sale of the Series B
Preferred pursuant to the Managing Dealer Agreement shall be less than $3,000,000 upon the
termination of such agreement, such Investor shall take all such action as may be requested by the
Company to facilitate the amendment of the Articles of Incorporation of the Company so as to remove
the rights of Series B Preferred Holders to elect the Series B Director;

               (3) For purposes of this Section 17, in determining the aggregate gross proceeds resulting
from the sale of the Series B Preferred pursuant to the Managing Dealer Agreement, there shall not
be included any proceeds resulting from the sale of shares of the Series B Preferred pursuant to
the Existing Preemptive Rights; and

               (4) In the event of an Initial Public Offering or Change of Control, such Investor shall (i)
take all such action as may be requested by the Company to facilitate the amendment of the Articles
of Incorporation of the Company so as to remove the rights of the Series B Preferred Holders to
elect the Series B Director; (ii) not exercise its right to elect the Series B Director as provided
for in the Company’s Articles of Incorporation; and (iii) take all such action as may be requested
by the Company to remove the Series B Director, if any, then serving on the Board.

17

 

          17.2 Voting Shares. Each Party to this Agreement agrees to hold all of its Common
Shares and Preferred Shares and any and all other voting securities of the Company legally or
beneficially acquired by each such Party after the date hereof (the “Voting Shares”)
subject to, and to vote such shares (and consent to actions taken by written consent) in accordance
with, the provisions of this Section 17. In the event that the Articles of Incorporation of the
Company are required to be amended by the terms of Section 17.1 above, each Party shall vote all of
its Voting Shares (and consent to actions taken by written consent) in favor of such amendment
pursuant to the terms of Section 17.1 above.

          17.3 Successors in Interest. The provisions of this Section 17 shall be binding upon
and inure to the benefit of all transferees or assignees of the Voting Shares. The Company shall
not permit the transfer of any of the Voting Shares on its books or issue a new certificate
representing any of the Voting Shares unless and until the person to whom such security is to be
transferred agrees to be bound by the terms and conditions of this Agreement.

          17.4 Legend Requirement. In addition to other legends that are required, either by
agreement or by the relevant federal or state securities laws, each certificate representing any of
the Voting Shares shall be marked by the Company with a legend substantially in the following form:

THE SHARES EVIDENCED HEREBY ARE SUBJECT TO CERTAIN VOTING
RESTRICTIONS AS SET FORTH IN AN AMENDED AND RESTATED INVESTORS
RIGHTS AGREEMENT DATED [______ ___], 2004, BY AND AMONG THE
REGISTERED HOLDER, THE CORPORATION AND OTHERS (A COPY OF WHICH MAY
BE OBTAINED FROM THE COMPANY) AND BY ACCEPTING ANY INTEREST IN SUCH
SHARES, THE PERSON HOLDING SUCH INTEREST SHALL BE DEEMED TO AGREE TO
AND SHALL BE BOUND BY ALL THE PROVISIONS OF SAID AGREEMENT.

          17.5 Specific Performance. The Parties recognize that irreparable injury will result
from a breach of any provision of this Section 17 and that money damages will be inadequate to
fully remedy the injury. Accordingly, in the event of a breach or threatened breach of this
Section 17, any Party who may be injured (in addition to any other remedies which may be available
to that Party) will be entitled to one or more preliminary or permanent orders (i) restraining and
enjoining any act which would constitute a breach, or (ii) compelling the performance of any
obligation which, if not performed, would constitute a breach.

     18. Governing Law; Jurisdiction and Venue. This Agreement shall be governed in all
respects by the internal laws of the State of California, without giving effect to principles of
conflicts of laws. The Parties submit to the jurisdiction of the Courts of the County of Orange,
State of California, or a Federal Court empanelled in the State of California for the resolution of
all legal disputes arising under the terms of this Agreement.

     19. Entire Agreement. This Agreement and, as applicable, the Purchase Documents,
constitute the full and entire understanding and agreement among the parties regarding the
transactions contemplated herein and therein. Except as otherwise expressly provided herein and

18

 

therein, the provisions hereof shall inure to the benefit of, and be binding upon, the successors,
assigns, heirs, executors and administrators of the parties hereto.

     20. Notices, etc. All notices required or permitted hereunder shall be in writing and
shall be deemed effectively given (i) upon personal delivery to the party to be notified, (ii)
three days after deposit in the United States mail, postage prepaid and properly addressed to the
party to be notified as set forth on the signature page hereof or at such other address as such
party may designate by ten days’ advance written notice to the other parties hereto, or (iii) when
transmitted if transmitted by telecopy (to be followed by U.S. mail), electronic or digital
transmission method. In each case notice shall be sent to (a) if to a New Investor, to the address
of such New Investor as set forth in Schedule A attached hereto; (b) if to an Existing
Investor, to the address of such Existing Investor as set forth on the signature page to the Prior
Agreement; (c) if to a Principal Shareholder, to the address of such Principal Shareholder as set
forth on Schedule B attached hereto; and (d) if to the Company, to the address set forth on
the signature page hereto; or in all cases, at such other address as a Party may designate by ten
(10) days’ advance written notice to the other Parties pursuant to the provisions of this Section
20.

     21. Counterparts. This Agreement may be executed in any number of counterparts, each
of which may be executed by fewer than all of the parties hereto, each of which shall be
enforceable against the parties actually executing such counterparts, and all of which together
shall constitute one and the same instrument. Signatures to this Agreement may be transmitted by
facsimile and such signatures shall be deemed to be originals.

     22. Amendment. Subject to Section 15.10 hereof, any provision of this Agreement may
be amended, waived, modified, discharged or terminated only with the written consent of the Company
and the Holders of a majority in interest of the Registrable Securities. Any amendment or waiver
effected in accordance with this paragraph will be binding upon the Company and each holder of any
securities subject to this Agreement (including securities into which such securities are
convertible) and future holders of all such securities. Any Holder may waive his or her rights or
the Company’s obligations hereunder without obtaining the consent of any other person.
Notwithstanding the foregoing, any purchaser purchasing Series B Preferred pursuant to any of the
Purchase Documents after the date hereof, as well as any purchaser purchasing shares of one or more
series of Preferred Shares to be designated in the future, may be required by the Company to
execute a signature page to this Agreement (after such purchaser has been provided with a copy of
this Agreement and an opportunity to review this Agreement) upon which execution such purchaser
shall be deemed a party hereto and the Company shall be authorized to unilaterally amend
Schedule A hereto to reflect the addition of any such purchaser as a New Investor.

     23. Successors and Assigns. Except as otherwise provided herein, the provisions
hereof shall inure to the benefit of, and be binding upon, the successors, assigns, heirs,
executors and administrators of the parties hereto.

     24. Severability. If any provision of this Agreement is held to be invalid or
unenforceable to any extent in any context, it shall nevertheless be enforced to the fullest extent
allowed by law in that and other contexts, and the validity and force of the remainder of this
Agreement shall not be affected thereby.

19

 

     25. Attorneys’ Fees. In the event that any dispute among the parties to this
Agreement should result in litigation, the prevailing party in such dispute shall be entitled to
recover from the losing party all reasonable fees, costs and expenses of enforcing any right of
such prevailing party under or with respect to this Agreement, including without limitation, such
reasonable fees and expenses of attorneys and accountants, which shall include, without limitation,
all reasonable fees, costs and expenses of appeals.

     26. Titles and Subtitles. The titles and subtitles used in this Agreement are used
for convenience only and are not to be considered in construing or interpreting this Agreement.

     27. Prior Agreement. The Parties who are parties to the Prior Agreement hereby agree
that, upon the effectiveness of this Agreement, the Prior Agreement shall be superseded and
replaced in its entirety by this Agreement; provided, however, that the effectiveness of this
Agreement shall not affect the Existing Preemptive Rights of the Existing Investors as applied to
the Series B Preferred.

     28. Effective Date of Agreement. This Agreement shall become effective upon the first
closing in the Company’s offering of its Series B Preferred, subject to the execution of this
Agreement by the Company and the holders of a majority of the outstanding shares of Series A
Preferred.

[Signature Page Follows]

20

 

     IN WITNESS WHEREOF, the parties have executed this Amended and Restated Investors Rights
Agreement as of the date first set forth above.

	 	 	 	 	 	 	 	 	 	 	 
	OCULUS INNOVATIVE SCIENCES, INC.	 	 	 	 	 	 	 	 
	 
	 	 	 	 	 	 	 	 	 	 
	By:
	 	/s/ Hojabr Alimi	 	 	 	 	 	 	 	 
	 

	 	 	 	 	 	 	 	 	 	 
	Name:
	 	Hojabr Alimi	 	 	 	 	 	 	 	 
	 

	 	 	 	 	 	 	 	 	 	 
	Title:
	 	President & CEO	 	 	 	 	 	 	 	 
	 

	 	 	 	 	 	 	 	 	 	 
	Address:

	 	1129 No. McDowell Blvd.	 	 	 	 	 	 	 	 
	 

	 	Petaluma, CA 94954	 	 	 	 	 	 	 	 
	Fax No.:

	 	707-283-0551	 	 	 	 	 	 	 	 
	 
	 	 	 	 	 	 	 	 	 	 
	INVESTORS	 	 	 	PRINCIPAL SHAREHOLDERS	 	 
	 
	 	 	 	 	 	 	 	 	 	 
	 	 	 	 	 	 	 	 	 
	 
	 	 	 	 	 	 	 	 	 	 
	By:

	 	 	 	 	 	By:	 	 	 	 
	 

	 	 
	 	 	 	 	 	 	 	 
	Print Name:

	 	 	 	 	 	Print Name: 	 	 	 	 
	 

	 	 
	 	 	 	 	 	 	 	 
	Title:
	 	 	 	 	 	 	 	 	 	 
	 

	 	 	 	 	 	 	 	 	 	 
	 
	 	 	 	 	 	 	 	 	 	 
	BROOKSTREET SECURITIES CORPORATION	 	 	 	HOLDERS OF MANAGING DEALER WARRANTS	 	 
	(for purposes of Sections 2-12 only)	 	 	 	(for purposes of Sections 2-12 only)	 	 
	 
	 	 	 	 	 	 	 	 	 	 
	 
	 	 	 	 	 	 	 	 	 	 
	By:

	 	 	 	 	 	By:	 	 	 	 
	 

	 	 
	 	 	 	 	 	 	 	 
	Print Name:

	 	 	 	 	 	Print Name: 	 	 	 	 
	 

	 	 
	 	 	 	 	 	 	 	 
	Title:

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[SIGNATURE PAGE TO AMENDED AND RESTATED INVESTORS RIGHTS AGREEMENT]

21

 

SCHEDULE A

New Investors

	 	 	 
	Name	 	Address and Fax Number
	 
	 	 

 

 

SCHEDULE B

Principal Shareholders

	 	 	 
	Name	 	Address and Fax Number
	Akihisa Akao

	 	5-26-11 Nakagawa Tsuzuki-Ku

Yokohoma, Kanagawa 224-0001

Japan

Fax No.:                                                             
	 
	 	 
	Hojabr Alimi

	 	1129 No. McDowell Blvd.

Petaluma, CA 94954

Fax No.: 707-283-0551
	 
	 	 
	Richard Conley

	 	17331 Hillside Drive

Sonoma, CA 95476

Fax No.:                                                             
	 
	 	 
	Greg French

	 	941 Birkdale Court

Windsor, CA 95492

Fax No.:                                                             
	 
	 	 
	Thomas Moore

	 	68 Abbott Road

Wellesley Hills, MA 02481

Fax No.:exv4w7

 

Exhibit 4.7

FORM OF PROMISSORY NOTE

[Note No. X-XXX]

			
	 	 	 
	$                                         
	 	                                        ,200___
	 
	 	San Jose, California

     The undersigned (“Borrower”) promises to pay to the order of VENTURE LENDING & LEASING III,
INC., a Maryland corporation (“Lender”), at its office at 2010 North First Street, Suite 310, San
Jose, California 95131, or at such other place as Lender may designate in writing, in lawful money
of the United States of America, the principal sum of                                                              Dollars
($                    ), with Basic Interest thereon (except as otherwise provided herein) from the date
hereof until maturity, whether scheduled or accelerated, at a fixed rate per annum equal to [ the
Prime Rate on the Business Day Lender prepares the Note plus 5.797%, but in no event less than
9.797%; (the “Designated Rate”) [, and a Terminal Payment in the sum of 
          [5.00% of face amount]        Dollars ($                    ) payable on the Maturity Date.]

          This Note is one of the Notes referred to in, and is entitled to all the benefits of, a Loan
and Security Agreement dated as of March___, 2004, between Borrower and Lender (the “Loan
Agreement”). Each capitalized term not otherwise defined herein shall have the meaning set forth
in the Loan Agreement. The Loan Agreement contains provisions for the acceleration of the maturity
of this Note upon the happening of certain stated events.

     Principal of and interest on this Note shall be payable as follows:

     On the Borrowing Date, Borrower shall pay (i) interest at the Designated Rate on the
outstanding principal balance of this Note for the period from the Borrowing Date through 
[the last day of the same month]___; and (ii) a first (1st) amortization installment
of principal and Basic Interest at the Designated Rate in the amount of                                         , in
advance for the month of [first full month after Borrowing Date] and (iii) a thirty-third
(33rd) amortization installment of principal and Basic Interest at the Designated Rate in the
amount of $                     , in advance for the month of      [date of last regular amortization
payment]     .

     Commencing on the first day of the second full month after the Borrowing Date, and continuing
on the first day of each consecutive month thereafter, principal and Basic Interest at the
Designated Rate shall be payable, in advance, in thirty(30) equal consecutive installments of
                                                             Dollars ($                 
   ) each, with a thirty-first (31st)
installment equal to the entire unpaid principal balance and accrued Basic Interest at the
Designated Rate on                     , 200___. The Terminal Payment and unpaid expenses, fees,
interest and principal amount shall be due and payable on      [one month later]     ,
200___.]

     This Note may be voluntarily prepaid only as permitted under Section 2 of Part 2 of the
Supplement to the Loan Agreement.

     Any unpaid payments of principal or interest on this Note shall bear interest from their
respective maturities, whether scheduled or accelerated, at a rate per annum equal to the Default
Rate. Borrower shall pay such interest on demand.

     Interest, charges and fees shall be calculated for actual days elapsed on the basis of a
360-day year, which results in higher interest, charge or fee payments than if a 365-day year were
used. In no event shall Borrower be obligated to pay interest, charges or fees at a rate in excess
of the highest rate permitted by applicable law from time to time in effect.

 

 

     If Borrower is late in making any payment under this Note by more than five (5) days, Borrower
agrees to pay a “late charge” of five percent (5%) of the installment due, but not less than fifty
dollars ($50.00) for any one such delinquent payment. This late charge may be charged by Lender
for the purpose of defraying the expenses incidental to the handling of such delinquent amounts.
Borrower acknowledges that such late charge represents a reasonable sum considering all of the
circumstances existing on the date of this Note and represents a fair and reasonable estimate of
the costs that will be sustained by Lender due to the failure of Borrower to make timely payments.
Borrower further agrees that proof of actual damages would be costly and inconvenient. Such late
charge shall be paid without prejudice to the right of Lender to collect any other amounts provided
to be paid or to declare a default under this Note or any of the other Loan Documents or from
exercising any other rights and remedies of Lender.

     This Note shall be governed by, and construed in accordance with, the laws of the State of
California.

	 	 	 	 	 	 	 
	 	 	OCULUS INNOVATIVE SCIENCES, INC.	 	 
	 
	 	 	 	 	 	 
	 

	 	By:	 	 	 	 
	 

	 	 	 	 

	 	 
	 

	 	Name:	 	 	 	 
	 

	 	 	 	 

	 	 
	 

	 	Its:

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