Document:

EXHIBIT 4.27

THIS WARRANT AND THE SHARES OF COMMON STOCK ISSUABLE UPON THE EXERCISE OF THIS
WARRANT (COLLECTIVELY, THE "SECURITIES") HAVE NOT BEEN REGISTERED UNDER THE
SECURITIES ACT OF 1933, AS AMENDED (THE "SECURITIES ACT"), AND MAY NOT BE
OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT, OR
PURSUANT TO AN AVAILABLE EXEMPTION FROM THE REGISTRATION REQUIREMENTS UNDER THE
SECURITIES ACT.

                               WARRANT TO PURCHASE

                    COMMON STOCK, PAR VALUE $.00001 PER SHARE

                                       OF

                          ADVANCED VIRAL RESEARCH CORP.

     This certifies that, for value received, [Name of Purchaser], or registered
assigns ("Warrantholder"), is entitled to purchase from ADVANCED VIRAL RESEARCH
CORP. (the "Company"), subject to the provisions of this Warrant, at any time
and from time to time until 5:00 p.m. Eastern Standard Time on February 28,
2005, _______ shares of the Company's Common Stock, par value $.00001 per share
("Warrant Shares"). The purchase price payable upon the exercise of this Warrant
shall be $.33 per Warrant Share. The Warrant Price and the number of Warrant
Shares which the Warrantholder is entitled to purchase is subject to adjustment
upon the occurrence of the contingencies set forth in Section 3 of this Warrant,
and as adjusted from time to time, such purchase price is hereinafter referred
to as the "Warrant Price."

         This Warrant is subject to the following terms and conditions:

1.   Exercise of Warrant.
     -------------------

         (a)  This Warrant may be exercised in whole or in part but not for a
              fractional share. Upon delivery of this Warrant at the offices of
              the Company or at such other address as the Company may designate
              by notice in writing to the registered holder hereof with the
              Subscription Form annexed hereto duly executed, accompanied by
              payment of the Warrant Price for the number of Warrant Shares
              purchased (in cash, by certified, cashier's or other check
              acceptable to the Company, by Common Stock of the Company having a
              Market Value (as hereinafter defined) equal to the aggregate
              Warrant Price for the Warrant Shares to be purchased, or any
              combination of the foregoing), the registered holder of this
              Warrant shall be entitled to receive a certificate or certificates
              for the Warrant Shares so purchased. Such certificate or
              certificates shall be promptly delivered

<PAGE>

              to the Warrantholder. Upon any partial exercise of this Warrant,
              the Company shall execute and deliver a new Warrant of like tenor
              for the balance of the Warrant Shares purchasable hereunder.

         (b)  In lieu of exercising this Warrant pursuant to Section 1(a), the
              holder may elect to receive shares of Common Stock equal to the
              value of this Warrant determined in the manner described below (or
              any portion thereof remaining unexercised) upon delivery of this
              Warrant at the offices of the Company or at such other address as
              the Company may designate by notice in writing to the registered
              holder hereof with the Notice of Cashless Exercise Form annexed
              hereto duly executed. In such event the Company shall issue to the
              holder a number of shares of the Company's Common Stock computed
              using the following formula:

                                   X = Y (A-B)
                                       -------
                                        A

Where X = the number of shares of Common Stock to be issued to the holder.

      Y = the number of shares of Common Stock purchasable under this Warrant
          (at the date of such calculation).

      A = the Market Value of the Company's Common Stock on the business day
          immediately preceding the day on which the Notice of Cashless Exercise
          is received by the Company.

      B = Warrant Price (as adjusted to the date of such calculation).

         (c)  The Warrant Shares deliverable hereunder shall, upon issuance, be
              fully paid and non_assessable and the Company agrees that at all
              times during the term of this Warrant it shall cause to be
              reserved for issuance such number of shares of its Common Stock as
              shall be required for issuance and delivery upon exercise of this
              Warrant.

         (d)  For purposes of this Warrant, the Market Value of a share of
              Common Stock on any date shall be equal to (i) the closing bid
              price per share as published by a national securities exchange on
              which shares of Common Stock (or other units of the security) are
              traded (an "Exchange") on such date or, if there is no bid for
              Common Stock on such date, the bid price on such exchange at the
              close of trading on the next earlier date or, (ii) if shares of
              Common Stock are not listed on a national securities exchange on
              such date, the closing bid price per share as published on the
              National Association of Securities Dealers Automatic Quotation
              System ("NASDAQ") National Market System if the shares are quoted
              on such system on such date, or (iii) the closing bid price in the
              over-the-counter market at the close of trading on such date if
              the shares are not traded on an exchange or listed on the NASDAQ
              National Market System, or (iv) if the Common Stock is not traded
              on a national securities exchange or in the over-the-counter
              market, the fair market value of a share of Common Stock on such
              date as determined in good faith by the Board of Directors. If the
              holder disagrees with the determination of the Market Value of any
              securities of the Company determined by the Board of Directors
              under Section 1(d)(iv) the Market Value of such securities shall
              be determined by an independent appraiser acceptable to the
              Company and the holder (or, if they cannot agree on such an
              appraiser,

<PAGE>

              by an independent appraiser selected by each of them, and Market
              Value shall be the median of the appraisals made by such
              appraisers). If there is one appraiser, the cost of the appraisal
              shall be shared equally between the Company and the holder. If
              there are two appraisers, each of the Company and the holder shall
              pay for its own appraisal.

2.       Transfer or Assignment of Warrant.
         ---------------------------------

              (a) Any assignment or transfer of this Warrant shall be made by
                  surrender of this Warrant at the offices of the Company or at
                  such other address as the Company may designate in writing to
                  the registered holder hereof with the Assignment Form annexed
                  hereto duly executed and accompanied by payment of any
                  requisite transfer taxes, and the Company shall, without
                  charge, execute and deliver a new Warrant of like tenor in the
                  name of the assignee for the portion so assigned in case of
                  only a partial assignment, with a new Warrant of like tenor to
                  the assignor for the balance of the Warrant Shares
                  purchasable.

              (b) Prior to any assignment or transfer of this Warrant, the
                  holder thereof shall deliver an opinion of counsel to the
                  Company to the effect that the proposed transfer may be
                  effected without registration under the Act.

3.       Adjustment of Warrant Price and Warrant Shares -- Anti-Dilution
         ---------------------------------------------------------------
         Provisions.
         -----------

         A. (1) Except as hereinafter provided, in case the Company shall at any
time after the date hereof issue any shares of Common Stock (including shares
held in the Company's treasury) without consideration, then, and thereafter
successively upon each issuance, the Warrant Price in effect immediately prior
to each such issuance shall forthwith be reduced to a price determined by
multiplying the Warrant Price in effect immediately prior to such issuance by a
fraction:

                  (a)      the numerator of which shall be the total number of
                           shares of Common Stock outstanding immediately prior
                           to such issuance, and
                  (b)      the denominator of which shall be the total number of
                           shares of Common Stock outstanding immediately after
                           such issuance.

     For the purposes of any computation to be made in accordance with the
provisions of this clause (1), the following provisions shall be applicable:

                  (i)          Shares of Common Stock issuable by way of
                               dividend or other distribution on any stock of
                               the Company shall be deemed to have been issued
                               and to be outstanding at the close of business on
                               the record date fixed for the determination of
                               stockholders entitled to receive such dividend or
                               other distribution and shall be deemed to have
                               been issued without consideration. Shares of
                               Common Stock issued otherwise than as a dividend,
                               shall be deemed to have been issued and to be
                               outstanding at the close of business on the date
                               of issue.

                  (ii)         The number of shares of Common Stock at any time
                               outstanding shall not include any shares then
                               owned or held by or for the account of the
                               Company.

<PAGE>

                      (2) In case the Company shall at any time subdivide or
                  combine the outstanding shares of Common Stock, the Warrant
                  Price shall forthwith be proportionately decreased in the case
                  of the subdivision or proportionately increased in the case of
                  combination to the nearest one cent. Any such adjustment shall
                  become effective at the close of business on the date that
                  such subdivision or combination shall become effective.

         B. In the event that the number of outstanding shares of Common Stock
is increased by a stock dividend payable in shares of Common Stock or by a
subdivision of the outstanding shares of Common Stock, which may include a stock
split, then from and after the time at which the adjusted Warrant Price becomes
effective pursuant to the foregoing Subsection A of this Section by reason of
such dividend or subdivision, the number of shares issuable upon the exercise of
this Warrant shall be increased in proportion to such increase in outstanding
shares. In the event that the number of outstanding shares of Common Stock is
decreased by a combination of the outstanding shares of Common Stock, then, from
and after the time at which the adjusted Warrant Price becomes effective
pursuant to such Subsection A of this Section by reason of such combination, the
number of shares issuable upon the exercise of this Warrant shall be decreased
in proportion to such decrease in outstanding shares.

         C. In the event of an adjustment of the Warrant Price, the number of
shares of Common Stock (or reclassified stock) issuable upon exercise of this
Warrant after such adjustment shall be equal to the number determined by
dividing:

                  (1) an amount equal to the product of (i) the number of shares
                      of Common Stock issuable upon exercise of this Warrant
                      immediately prior to such adjustment, and (ii) the Warrant
                      Price immediately prior to such adjustment, by

                  (2) the Warrant Price immediately after such adjustment.

         D. In the case of any reorganization or reclassification of the
outstanding shares of Common Stock (other than a change in par value, or from
par value to no par value, or from no par value to par value, or as a result of
a subdivision or combination) or in the case of any consolidation of the Company
with, or merger of the Company with, another corporation, or in the case of any
sale, lease or conveyance of all, or substantially all, of the property, assets,
business and goodwill of the Company as an entity, the holder of this Warrant
shall thereafter have the right upon exercise to purchase the kind and amount of
shares of stock and other securities and property receivable upon such
reorganization, reclassification, consolidation, merger or sale by a holder of
the number of shares of Common Stock which the holder of this Warrant would have
received had all Warrant Shares issuable upon exercise of this Warrant been
issued immediately prior to such reorganization, reclassification,
consolidation, merger or sale, at a price equal to the Warrant Price then in
effect pertaining to this Warrant (the kind, amount and price of such stock and
other securities to be subject to adjustment as herein provided).

<PAGE>

         E. In case the Company shall, at any time prior to the expiration of
this Warrant and prior to the exercise thereof, dissolve, liquidate or wind up
its affairs, the Warrantholder shall be entitled, upon the exercise thereof, to
receive, in lieu of the Warrant Shares of the Company which it would have been
entitled to receive, the same kind and amount of assets as would have been
issued, distributed or paid to it upon such Warrant Shares of the Company, had
it been the holder of record of shares of Common Stock receivable upon the
exercise of this Warrant on the record date for the determination of those
entitled to receive any such liquidating distribution. After any such
dissolution, liquidation or winding up which shall result in any distribution in
excess of the Warrant Price provided for by this Warrant, the Warrantholder may
at its option exercise the same without making payment of the aggregate Warrant
Price and in such case the Company shall upon the distribution to said
Warrantholder consider that the aggregate Warrant Price has been paid in full to
it and in making settlement to said Warrantholder, shall deduct from the amount
payable to such Warrantholder an amount equal to the aggregate Warrant Price.

         F. In case the Company shall, at any time prior to the expiration of
this Warrant and prior to the exercise thereof make a distribution of assets
(other than cash) or securities of the Company to its stockholders (the
"Distribution") the Warrantholder shall be entitled, upon the exercise thereof,
to receive, in addition to the Warrant Shares it is entitled to receive, the
same kind and amount of assets or securities as would have been distributed to
it in the Distribution had it been the holder of record of shares of Common
Stock receivable upon exercise of this Warrant on the record date for
determination of those entitled to receive the Distribution.

         G. Irrespective of any adjustments in the number of Warrant Shares and
the Warrant Price or the number or kind of shares purchasable upon exercise of
this Warrant, this Warrant may continue to express the same price and number and
kind of shares as originally issued.

4.   Officer's Certificate. Whenever the number of Warrant Shares and the
     Warrant Price shall be adjusted pursuant to the provisions hereof, the
     Company shall forthwith file, at its principal executive office a
     statement, signed by the Chairman of the Board, President, or one of the
     Vice Presidents of the Company and by its Chief Financial Officer or one of
     its Treasurers or Assistant Treasurers, stating the adjusted number of
     Warrant Shares and the new Warrant Price calculated to the nearest one
     hundredth and setting forth in reasonable detail the method of calculation
     and the facts requiring such adjustment and upon which such calculation is
     based. Each adjustment shall remain in effect until a subsequent adjustment
     hereunder is required. A copy of such statement shall be mailed to the
     Warrantholder.

5.   Charges, Taxes and Expenses. The issuance of certificates for Warrant
     Shares upon any exercise of this Warrant shall be made without charge to
     the Warrantholder for any tax or other expense in respect to the issuance
     of such certificates, all of which taxes and expenses shall be paid by the
     Company, and such certificates shall be issued only in the name of the
     Warrantholder.

<PAGE>

6.       Miscellaneous.
         --------------

         (a)  The terms of this Warrant shall be binding upon and shall inure to
              the benefit of any successors or assigns of the Company and of the
              holder or holders hereof and of the shares of Common Stock issued
              or issuable upon the exercise hereof.

         (b)  No holder of this Warrant, as such, shall be entitled to vote or
              receive dividends or be deemed to be a stockholder of the Company
              for any purpose, nor shall anything contained in this Warrant be
              construed to confer upon the holder of this Warrant, as such, any
              rights of a stockholder of the Company or any right to vote, give
              or withhold consent to any corporate action, receive notice of
              meetings, receive dividends or subscription rights, or otherwise.

              (c) Receipt of this Warrant by the holder hereof shall constitute
              acceptance of an agreement to the foregoing terms and conditions.

         (d)  The Warrant and the performance of the parties hereunder shall be
              construed and interpreted in accordance with the laws of the State
              of New York and the parties hereunder consent and agree that the
              State and Federal Courts which sit in the State of New York and
              the County of New York shall have exclusive jurisdiction with
              respect to all controversies and disputes arising hereunder.

     IN WITNESS WHEREOF, the Company has caused this Warrant to be signed by its
duly authorized officer and its corporate seal to be affixed hereto.

Dated: February 16, 2000

                           ADVANCED VIRAL RESEARCH CORP.

                           BY: /s/ Shalom Hirschman, M.D.
                               ------------------------------
                               Shalom Hirschman, M.D.
                               PresidentEXHIBIT 10.35

                              CONSULTING AGREEMENT
                              --------------------

         CONSULTING AGREEMENT dated as of the 7th day of February, 2000 by and
between Advanced Viral Research Corp., a Delaware corporation, with offices
located at 200 Corporate Boulevard South, Suite 4, Yonkers, New York 10701 (the
"Company") and Harbor View Group, Inc., a New York corporation, with offices
located at One Old Country Road, Carle Place, New York 11514 (the "Consultant").

                                    PREAMBLE:
                                    ---------

         A. Heretofore, Consultant has provided valuable services to the Company
in connection with the Company's search for a chief financial officer ("CFO")
and provided assistance to the Company in connection with its ultimate
engagement of Alan Gallantar as CFO.

         B. Consultant has considerable experience in corporate structuring,
financial transactions, financial public relations, corporate governance and
shareholder relations, which such experience it is willing to make available to
the Company.

         C. The Company desires to retain Consultant to provide the services
referred to in Paragraph B above, to provide additional advisory services as
requested, and to compensate Consultant for its prior contribution to the
Company as described in Paragraph A above.

         NOW, THEREFORE, in consideration of the promises and commitments set
forth herein, and for other good and valuable consideration, the receipt and
sufficiency of which are hereby acknowledged, the parties hereto, intending
legally to be bound, hereby agree as follows:

1. Term of Agreement. This Agreement shall commence as of the date hereof and
shall continue until December 31, 2000, unless sooner terminated in accordance
with the provisions of this Agreement.

2. Responsibilities of Consultant. Subject to the terms and conditions
hereinafter set forth, the Company hereby retains Consultant and Consultant
hereby agrees, to use its expertise to render assistance to the Company in
connection with the matters referred to in Preamble paragraphs A and B hereof.
Consultant shall devote such time as it deems necessary and required to carry
out its duties in assisting the Company hereunder. Consultant shall not have
authority to execute any agreements or make any commitments on behalf of the
Company, but Consultant may advise others that it is engaged as a consultant for
the Company. Consultant shall not be an employee or agent of the Company; all
services will be rendered as an independent contractor. Consultant shall act in
good faith to carry forward the reputation of the Company and shall take no
action which would jeopardize the Company from doing business anywhere in the
world.

<PAGE>

3. Compensation. As full compensation for its services hereunder Consultant
shall receive the following compensation: (a) a warrant to purchase 1,750,000
shares of the Company's Common Stock, par value $.00001 per share, at an
exercise price of $.21 per share, and (b) a warrant to purchase 1,750,000 shares
of the Company's Common Stock, par value $.00001 per share, at an exercise price
of $.26 per share. The warrants shall be exercisable in whole or in part at any
time and from time to time prior to 5:00 p.m. Eastern Standard Time on February
28, 2005, and shall otherwise contain substantially the same terms and
conditions as are set forth in the exhibit attached hereto as Exhibit A. Except
as otherwise agreed to in writing, the Company shall not be responsible to
reimburse Consultant for any out-of-pocket expenses incurred by Consultant in
connection with the performance of its duties hereunder.

         It is specifically understood that Consultant shall have the right to
engage experienced people or entities in the financial community to assist it in
the performance of its duties hereunder provided that such persons or entities
enjoy favorable reputations in the financial and business community and are
otherwise acceptable to the Company. Any compensation earned by such persons or
entities shall be the responsibility of Consultant, who shall have the right to
assign part of its warrant interest herein thereto, subject to all of the terms
and conditions of this Agreement.

         The warrants granted hereunder shall otherwise be non-transferable
provided, however, that Consultant shall have the right to transfer all or any
part of the warrants to any principal of Consultant, to the spouse or child of
any principal of Consultant or to any trust for the benefit of any of the
aforesaid persons if the provisions of such trust are permissive thereof. Any
such transfer shall be subject to the provisions of this Agreement and have the
terms of the warrants.

         Consultant represents that it is an Accredited Investor as that term is
defined in Rule 501 of Regulation D under the Securities Act of 1933.

4.       Transaction.
         -----------

         4.1 The Company shall have the absolute right, in the exercise of its
sole discretion, to accept or reject any proposal for investment brought to it
by Consultant. If, and at such time as, the Company shall enter into and
consummate a transaction with one or more private investors (other than those
security holders of the Company as of the date hereof), the Company will pay
Consultant a fee which shall be negotiated in good faith based upon the size and
terms of the investment secured by Consultant.

         4.2 If, during the term of this Agreement, Consultant introduces a
prospective investor to the Company and the Company consummates a transaction
with such investor during the term of this Agreement or within one year
thereafter, Consultant shall be entitled to compensation as referred to in this
Paragraph 4.

<PAGE>

5.       Property Rights of Parties.
         --------------------------

         5.1. Consultant shall not disclose any trade secrets of the Company,
directly or indirectly, nor use them in any way either during the term of this
Agreement or at any time thereafter except as required in the course of its
consulting. All files, records, documents, drawings, specifications, equipment
and similar items relating to the business of the Company, whether or not
prepared by Consultant, shall remain the exclusive property of the Company and
shall not be removed from the premises of the Company under any circumstances,
except in pursuit of the trade and business of the Company and as approved in
writing in advance by a senior officer of the Company.

         5.2. On the termination of this Agreement or whenever requested by the
Company, Consultant shall immediately deliver to the Company all property in
Consultant's possession or under Consultant's control belonging to the Company,
including, but not limited to, all accounting records, computer terminals and
tapes, disks, or other data storage mechanisms, accounting machines, and all
office furniture and fixtures, supplies and other personal property in the
possession or under the control of Consultant, in good condition, ordinary wear
and tear excepted, and including, without limitation, all correspondence files,
research data, and patent information or data, of every sort.

         5.3. Consultant does not claim any rights or interests in and to trade
secrets, formulas, devices, inventions, processes, patents, applications,
continuations, copyrights, trademarks, compilations of information, records,
specifications, rights, interests and data of any other sort, affecting or
pertaining directly or indirectly to the business of the Company as now
conducted, or to the patents, trade secrets, and other rights now owned by the
Company.

         5.4. Consultant hereby irrevocably releases and forever discharges the
Company, its successors, assigns, representatives, directors, officers,
employees and agents from any and all causes of action, suits, claims, debts,
accounts, reckonings, claims for attorneys fees, interests, contracts, promises,
damages and demands of any nature arising out of any services performed by
Consultant to the Company prior to the date hereof, including, without
limitation, any fees for finding any person, firm or entity employed by the
Company or which has invested in or provided financing for the Company.

6. Entire Agreement. This Agreement constitutes the entire Agreement of the
parties hereto with respect to the subject matter hereof and no amendment or
modification hereof shall be valid or binding unless made in writing and signed
by the party against whom enforcement thereof is sought.

7. Notices. Any notice required, permitted or desired to be given pursuant to
any of the provisions of this Agreement shall be deemed to have been
sufficiently given or served for all purposes if delivered in person or sent by
telephone facsimile or sent by certified mail, return receipt requested, or sent
by responsible overnight delivery service, postage and fees prepaid, to the
parties hereto at their respective addresses set forth in the preamble to this
Agreement. Either

<PAGE>

of the parties hereto may at any time and from time to time change the address
to which notice shall be sent hereunder by notice to the other party given under
this Section 7. The date of the giving of any notice sent by mail shall be three
business days following the date of the posting of the mail, the date delivered
in person, the next business day following delivery to an overnight delivery
service or the date sent by telephone facsimile, as applicable. All notices to
the Company, to be valid, shall simultaneously be delivered to Robert E.
Fischer, Wolf, Block, Schorr and Solis-Cohen, LLP, 250 Park Avenue, New York,
New York 10177.

8. No Assignment. This Agreement may not be assigned by Consultant. This
Agreement shall be binding upon Consultant and the Company and their respective
successors and assigns.

9. No Waiver. No course of dealing nor any delay on the part of the Company in
exercising any rights hereunder shall operate as a waiver of any such rights. No
waiver of any default or breach of this Agreement shall be deemed a continuing
waiver or a waiver of any other breach or default.

10. Governing Law. This Agreement shall be governed, interpreted and construed
in accordance with the substantive laws of the State of New York applicable to
Agreements entered into and to be performed entirely therein. Any suit, action
or proceeding with respect to this Agreement shall be brought exclusively in the
courts of the State of New York, County of New York or in the United States
District Court for the Southern District of New York.

11. Severability. If any clause, paragraph, section or part of this Agreement
shall be held or declared to be void, invalid or illegal, for any reason, by any
court of competent jurisdiction, such provision shall be ineffective but shall
not in any way invalidate or affect any other clause, paragraph, section or part
of this Agreement. The parties intend that all clauses, paragraphs, sections or
parts of this Agreement shall be enforceable to the fullest extent permitted by
law.

12. Counterparts. This Agreement may be executed in one or more counterparts,
each of which counterparts, when taken together, shall constitute but one and
the same agreement.

<PAGE>

         IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be
duly executed as of the day and year first above written.

                                                  ADVANCED VIRAL RESEARCH CORP.

                                                  By: /s/ Shalom Z. Hirschman, M
                                                      --------------------------
                                                  Name:  Shalom Hirschman, M.D.
                                                  Title: President

                                                  HARBOR VIEW GROUP, INC.

                                                  By: /s/ Lawrence J. Pomeranz
                                                      --------------------------
                                                  Name:  Lawrence J. Pomeranz
                                                  Title: Chairman

Agreed to as to Paragraph 5

/s/ Lawrence J. Pomeranz
-------------------------
    Lawrence J. Pomerantz

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