Document:

Employment Agreement dated March 18, 2009 with Henry J. Fuchs

 Exhibit 10.1 
 EMPLOYMENT AGREEMENT 
 THIS EMPLOYMENT AGREEMENT (“Agreement”) made as of
March 18, 2009 (“Effective Date”) by and between BioMarin Pharmaceutical Inc., a Delaware corporation (the “Company”) and Henry J. Fuchs (“Employee”). 
 NOW THEREFORE, for good and valuable consideration (the receipt and adequacy of which are hereby acknowledged and agreed) the parties hereby covenant and
agree as follows: 
 1. Title; Duties. The Company hereby employs the Employee as Senior Vice President and Chief Medical Officer to
perform such duties consistent with his title and position as may be determined and assigned to him by the Company’s Chief Executive Officer (“CEO”). The Employee shall be based in Novato, California, provided that Employee
acknowledges that his job duties may require significant travel. 
 2. Time and Effort. The Employee agrees to devote substantially
all of his professional employment time and effort to the performance of his duties as Senior Vice President and Chief Medical Officer for the Company and to perform such other duties consistent with his title and position as are reasonably assigned
him from time to time by the CEO. 
 3. Term. The Company agrees to employ the Employee in accordance with the terms of this
Agreement, which terms shall be effective commencing on the Effective Date and continuing thereafter until terminated pursuant to Section 6 or 7 hereof (the “Term” of this Agreement). A review of the
Employee’s total compensation will be made by the Board of Directors of the Company (“Board”) at least annually in or about December of each year based on the overall performance of the Company and the Company’s assessment
of the Employee’s contributions to the Company’s performance, although the Board shall not be under any obligation to make adjustments other than pursuant to its discretion. 
 4. Compensation; Benefits. 
 (a)
Base Salary. For all the services to be rendered by the Employee in any capacity hereunder, including services as an executive officer, the Company agrees to pay the Employee a base salary (“Base Salary”) of not less than
four hundred ten thousand dollars ($410,000) per annum. Base Salary shall be payable in approximately equal installments in accordance with the Company’s customary payroll practices. The foregoing annual compensation amount may be, from time to
time, adjusted above the Base Salary specified above by action of the Board or appropriate Committee of the Board. In the event the Base Salary is adjusted upward by the Board, such adjusted amount will be deemed to be the new Base Salary.

 (b) Annual Bonus. The Employee shall be entitled to participate in the Company’s generally applicable employee bonus program,
with such targets and metrics as may be approved by the Board from time to time. For the 2009 bonus plan, Employee’s target bonus will be 40% of Base Salary. Notwithstanding the fact that Employee was hired on March 2, 2009, any amounts
earned by Employee under the 2009 bonus plan shall not be prorated. 

 (c) Benefits Plans. The Employee also shall participate fully in all insurance, pension,
retirement, deferred compensation, stock and stock option, stock purchase or similar compensation and benefit plans and programs pursuant to the terms of such plans or programs. 
 (d) Vacation. The Employee shall be entitled to annual paid vacation time of four (4) weeks, accruing ratably over the course of each year of
employment, to be taken at such time or times as the Employee may select, consistent with his obligations hereunder. Vacation days not taken during an applicable fiscal year may be carried over to the extent permitted under the Company’s
vacation policy to the following fiscal year pursuant such policy. 
 (e) Expenses. The Company shall reimburse the Employee for all
reasonable and customary travel, business and entertainment expenses incurred in connection with the Employee’s performance of his services hereunder in accordance with the policies and procedures established by the Company and paid promptly
after the Employee makes a request therefore and no later than the end of the calendar year following the calendar year in which the expenses were incurred by the Employee. 
 (f) Withholding. The amounts payable pursuant to this Agreement shall be subject to withholding for appropriate taxes, assessments or withholdings
as required by applicable law. 
 5. Other Plans. The Company and the Employee hereby agree that nothing contained herein is intended
to or shall be deemed to affect any of the Employee’s rights as a participant under any retirement, stock option, stock purchase, pension, insurance, profit-sharing or similar plans of the Company now or hereafter declared to be in effect. The
Company recognizes that the Employee is induced to execute this Agreement and to accept compensation at the rate set forth herein in part because he expects to be a participant under such plans as are, from time to time, in effect for the
Company’s executives and/or employees in general. 
 6. Termination for Cause, Resignation Without Good Reason. 
 (a) Termination for Cause. This Agreement may be terminated for Cause (as defined below) by the Company before the expiration of the Term provided
for herein if, during the Term of this Agreement, the Employee (i) materially violates the provisions of the Non-Competition Agreement or the Confidentiality Agreements between the Company and Employee, (ii) is convicted of, or pleads
nolo contendere to, any crime involving misuse or misappropriation of money or other property of the Company or any felony; (iii) exhibits repeated willful or wanton failure or refusal to perform his duties in furtherance of the
Company’s business interest or in accordance with this Agreement, which failure or refusal is not remedied by the Employee within thirty (30) days after notice from the Company; (iv) commits an intentional tort against the Company,
which materially adversely affects the business of the Company; (v) commits any flagrant act of dishonesty or disloyalty or any act involving gross moral turpitude, which materially adversely affects the business of the Company; or
(vi) exhibits immoderate use of alcohol or drugs which, in the opinion of an independent physician selected by the Company, impairs the Employee’s ability to perform his duties hereunder (all of the foregoing clauses (i) through
(vi) constituting reasons for termination for “Cause”), provided that unsatisfactory business performance of the Company, or mere inefficiency, or good faith errors in judgment or discretion by the Employee shall not constitute
grounds for termination for Cause hereunder. In the event of a termination for Cause, the Company may by written notice immediately terminate his employment and, in that event, the Company shall be obligated only to pay the Employee the compensation
due him up to the date of termination, all accrued, vested or earned benefits under any applicable benefit plan and any other compensation to which the Employee is entitled under Section 4 up to and ending on the date of the
Employee’s termination. 

 (b) Resignation Without Good Reason. The benefits and compensation set forth in
Section 6(a) are the only compensation and benefits that the Employee will receive in the event that Employee resigns without Good Reason (as defined below). If the Employee resigns without Good Reason prior to a Change in Control (as
defined in the Company’s Change of Control Policy), the Employee agrees to give the Company at least four (4) weeks’ prior notice and in exchange the Company agrees to pay the Employee for all compensation Employee would be entitled
to pursuant to Section 4 for such four (4)-week period as if Employee had not resigned without Good Reason. Any resignation of the Employee hereunder, whether for Good Reason or otherwise, shall be deemed to include a resignation from
all positions and in all capacities with the Company and its subsidiaries, including, without limitation, membership on the boards of directors (and committees thereof) of subsidiaries of the Company, and the Employee shall execute such
documentation as requested by the Company with respect thereto. 
 7. Termination Without Cause; Resignation For Good Reason; Disability;
Death. 
 (a) Termination Without Cause; Resignation For Good Reason. The Company may terminate the Employee’s employment at
any time for any reason or no reason, upon written notice to the Employee. If (i) the Company terminates the Employee’s employment without Cause at any time prior to the end of the Term of the Agreement, or (ii) the Employee provides
the Company with written notice (a “Notice of Termination”) of his resignation for Good Reason (as defined below) at least four (4) weeks prior to the date of termination, then the Employee shall receive the Termination
Compensation (as defined below). 
 (b) Resignation for Good Reason. A resignation for any one or more of the following events, without
the written consent of Employee or his approval of such event in his capacity as Vice President, General Counsel, shall be referred to herein as “Good Reason”; 
 (i) a substantial reduction in the Employee’s duties, status, or reporting structure, in either case by reference to the position held by the
Employee on the Effective Date; 
 (ii) a relocation of the Employee’s assigned office more than fifty (50) miles from its
then-current location; 
 (iii) any decrease in the Employee’s Base Salary or a material decrease in his Company benefits in the
aggregate, other than as part of a reduction (not exceeding twenty-five percent) that equitably applies to all of the Company’s executive officers; or 
 (iv) a material breach of this Agreement by the Company. 
 (c) provided, however, that an event
that is or would constitute grounds for a resignation for Good Reason shall not constitute such grounds for a resignation for Good Reason unless (i) Employee first notifies the Company’s Board of Directors in writing of the event(s) within
ninety (90) days after the initial occurrence of the event, (ii) the Company does not cure such event(s) within thirty (30) days after its receipt of the Employee’s written notice, and (iii) the Employee does not terminate
his employment within thirty (30) days after the expiration of the cure period. Termination Compensation. For purposes of this Agreement, the term “Termination Compensation” shall mean: (i) one hundred forty percent
(140%) of Employee’s then current annual base salary which shall be payable in a lump sum within 2 weeks after separation of employment, conditioned on Employee executing the Company’s standard form severance and release agreement,
and shall be subject to customary withholding and other applicable payroll processes. Employee shall execute the Company’s standard form severance and release agreement within sixty (60) days after the Employee’s termination.

 (d) Employee’s Disability. The Company shall be entitled, by providing written notice to the
Employee, to terminate the Employee’s employment under this Agreement if the Employee shall become permanently disabled such that he is unable to carry out his duties hereunder for four (4) consecutive calendar months or for a period
aggregating one hundred twenty (120) days in any period of twelve (12) consecutive calendar months. If the Employee is eligible to receive benefits under the Company’s Long-Term Disability Plan, then the Company will pay the Employee
additional compensation so that the total received by the Employee (after taking into consideration the amounts payable to the Employee under the Long-Term Disability Plan) equals the Termination Compensation. If the Employee is not eligible to
receive benefits under such plan, then he will upon termination of his employment for permanent disability be entitled to receive the full Termination Compensation. Any delay or forbearance by the Company in exercising any such right to terminate
this Agreement shall not constitute a waiver thereof. 
 (e) Employee’s Death. The Employee’s employment will immediately
terminate upon the death of the Employee. The Employee’s surviving designated beneficiary, or, if none, the Employee’s estate, shall be entitled to receive the compensation due the Employee up to the date of the Employee’s death, all
accrued, vested or earned benefits under any applicable benefit plan and any other compensation to which the Employee is entitled under this Agreement up to and ending on the date of the Employee’s death. 
 8. Choice of Law; Venue. This Agreement shall be construed and performed in accordance to the laws (but not the conflicts of laws) of the State of
California. Venue of any proceeding shall be exclusively in the County of Marin in the foregoing state, and both parties consent and agree to such exclusive venue. 
 9. Arbitration. 
 (a) The Employee and the Company understand that litigation is a costly and
time-consuming process and agree that they will exclusively resolve any disputes between them by binding arbitration. The Employee and the Company understand that this agreement to arbitrate covers all disputes that the Company may have against the
Employee, or that the Employee might have against the Company or its related entities or employees, including those that relate to the Employee’s employment or termination of employment (for example claims of unlawful discrimination or
harassment). 
 (b) The arbitration will be conducted by an impartial arbitrator experienced in employment law (selected from either the JAMS
or the American Arbitration Association (at the Company’s election) panel of arbitrators) in accordance with the applicable entity’s then current employment arbitration rules (except as otherwise provided in this agreement or unless the
parties agree to use the then-current commercial arbitration rules). The Employee and the Company waive the right to institute a court action, except for requests for injunctive relief pending arbitration, and understand that they are giving up
their right to a jury trial. The parties shall be entitled to reasonable discovery. The arbitrator’s award and opinion shall be in writing and in the form typically rendered in labor and employment arbitrations. 
 (c) The Company will pay any filing fee and the fees and costs of the arbitrator, unless the Employee initiates the claim, in which case the Employee only
will be required to contribute an amount equal to the filing fee for a claim initiated in a court of general jurisdiction in the State of California. The Employee and the Company each shall be responsible for their own attorneys’ fees and
costs; provided, however, the arbitrator may award attorneys’ fees to the prevailing party, if permitted by applicable law. This arbitration agreement does not prohibit either the Employee or the Company from filing a claim with
an administrative agency (e.g., the EEOC), nor does it apply to claims for workers’ 

 
compensation or unemployment benefits, or claims for benefits under an employee welfare or pension plan that specifies a different dispute resolution
procedure. The arbitration shall take place in Marin County, California unless the Employee and the Company agree otherwise, 
 10.
Notices. All notices provided for or permitted to be given pursuant to this Agreement must be in writing. All notices shall be given to the other party by personal delivery, overnight courier (with receipt signature), or facsimile
transmission (with “answerback” confirmation of transmission), to the Company or the Employee at the Company’s principal executive offices if to the Company or to the residential address of the Employee as contained in Employee’s
personnel file if to Employee. Each such notice shall be deemed effective upon the date of actual receipt in the case of personal delivery, receipt signature in the case of overnight courier, or confirmation of transmission in the case of facsimile.

 11. Entire Agreement; Amendment. This Agreement contains the sole and entire agreement of the parties and supersedes all prior
agreements and understandings between the Employee and the Company and cannot be modified or changed by any oral or verbal promise or statement by whomsoever made; nor shall any written modification of it be binding upon the Company until such
written modification shall have been approved in writing by the CEO or the Board. 
 12. Waiver; Consent. In the event any term or
condition contained in this Agreement should be breached by any party and thereafter waived or consented to by the other party, which waiver or consent must be effectuated by a written instrument signed by the party against whom any waiver or
consent is sought (and, in the case of the Company, approved by the CEO or the Board), such waiver or consent shall be limited to the particular breach so waived or consented to and shall not be deemed to waive or consent to any other breach
occurring prior or subsequent to the breach so waived or consented to. 
 13. Severability. If any provisions of this Agreement or the
application thereof to any person or circumstances shall be invalid or unenforceable to any extent, the remainder of this Agreement and the application of such provisions to other persons or circumstances shall not be affected thereby and shall be
enforced to the extent permitted by law. 
 14. Survival. The provisions hereof which are to be performed or observed after the
termination of this Agreement, and the representations, covenants and agreements of the parties contained herein with respect thereto shall survive the termination of this Agreement and be effective according to their terms. 
 15. Successors. All of the terms and provisions of this Agreement shall be binding upon and shall inure to the benefit of and be enforceable by
and against the parties to this Agreement and the respective heirs, executors, and successors in interest; provided, however, that the duties of the Employee hereunder are personal in nature and may not be delegated without a written
consent of the Company. 
 16. Assignment. This Agreement and the rights and benefits contained herein may not be assigned by either
party hereto, except by the Company in connection with a merger, consolidation, share exchange, business combination or other reorganization of the Company or a sale of all or substantially all of the Company’s business or assets. 

17. Certain Representations, Covenants and Acknowledgements. 
 (a) The Employee represents that he is not subject to any employment, confidentiality, or other agreement or restriction that would prevent him from fully satisfying his duties under this Agreement or that would be
violated if he did so. 

 (b) Without the Company’s prior written approval, the Employee agrees not to: (i) disclose
proprietary information belonging to a former employer or other entity without its written permission; (ii) contact any former employer’s customers or employees to solicit their business or employment on behalf of the Company; or
(iii) distribute announcements about or otherwise publicize his employment with the Company. 
 (c) The Employee acknowledges that he is
free to seek advice from independent counsel with respect to this Agreement and the Employee has obtained such advice. The Employee is not relying on any representation or advice from the Company or any of its officers, directors, attorneys or other
representatives regarding this Agreement, its content or effect. 
 18. Construction. The masculine pronoun, wherever used herein,
shall be construed to include the feminine and the neuter, where appropriate, The singular form, wherever used herein, shall be construed to include the plural, where appropriate. 
 19. Drafting. The parties represent and acknowledge that they both have participated in the preparation and drafting of this Agreement and have
each given their approval to all of the language contained in this Agreement, and it is expressly agreed and acknowledged that if either party later claims that there is an ambiguity in the language of this Agreement, there shall be no presumption
that such ambiguity be construed for or against either party hereto. 
 20. Counterparts. This Agreement may be executed and delivered
(including by facsimile transmission) in one or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. 
 21. Compliance with Section 409A the Internal Revenue Code of 1986, as amended. If any amounts or benefits payable under this Agreement on
account of Employee’s termination of employment constitute deferred compensation subject to Section 409A of the Internal Revenue Code of 1986, as amended (the “Code”), no payments or benefits shall be paid or provided until
Employee incurs a separation from service within the meaning of Treas. Reg. § 1.409A-1(h) from the Company and any entity that would be considered a single employer with the Company under Code Sections 414(b) or 414(c) (“Separation from
Service”). If, at the time of Employee’s Separation from Service, the Employee is a “specified employee” (within the meaning of Code Section 409A and Treas. Reg. §1.409A-3(i)(2)), the Company will not pay or provide any
“Specified Benefits” (as defined herein) during the six-month period (the “409A Suspension Period”) beginning immediately after the Employee’s Separation from Service. For purposes of this Agreement, “Specified
Benefits” are any amounts or benefits that would be subject to Code Section 409A penalties if the Company were to pay them, pursuant to this Agreement, on account of the Employee’s Separation from Service. 
 This Agreement is intended to comply with (or be exempt from) Code Section 409A, and the Company shall have complete discretion to interpret and
construe this Agreement and any associated documents in any manner that establishes an exemption from (or otherwise conforms them to) the requirements of Code Section 409A. If, for any reason including imprecision in drafting, the Agreement
does not accurately reflect its intended establishment of an exemption from (or compliance with) Code Section 409A, as demonstrated by consistent interpretations or other evidence of intent, the provision shall be considered ambiguous and shall
be interpreted by the Company in a fashion consistent herewith, as determined in the sole and absolute discretion of the Company. The Company reserves the right to unilaterally amend this Agreement without the consent of the Employee in order to
accurately reflect its correct interpretation and operation, as well as to maintain an exemption from or compliance with Code Section 409A. Nevertheless, and notwithstanding any other provision of this Agreement, neither the Company nor any of
its employees, directors, or their agents shall have any obligation to mitigate, nor to hold the Employee harmless from, any or all taxes (including any imposed under Code Section 409A) arising under this Agreement. 

 IN WITNESS WHEREOF, the parties to this Agreement have executed this Agreement as of the date indicated
above. 
  

			
	BIOMARIN PHARMACEUTICAL INC.
		
	By:	 	/s/ Jean-Jacques Bienaimé
		 	Name: Jean-Jacques Bienaimé
		 	Its: Chief Executive Officer

  

			
	EMPLOYEE
		
	By:	 	/s/ Henry J. Fuchs
	Henry J. FuchsFirst Amendment to Loan, Guaranty and Security Agreement

 Exhibit 10.1 
 FIRST AMENDMENT TO LOAN, GUARANTY AND SECURITY AGREEMENT 
 FIRST AMENDMENT TO LOAN, GUARANTY
AND SECURITY AGREEMENT (this “Agreement”), dated as of March 18, 2009, among Design Within Reach, Inc. (“Borrower”), the financial institutions party hereto from time to time (together with their respective
successors and assigns, “Lenders”) and Wells Fargo Retail Finance, LLC, as Agent for all Lenders. Terms not defined herein have the meanings given to them in the Loan Agreement (as hereinafter defined). 
 BACKGROUND 
 A.
Borrower, Lenders and Agent are party to that certain Loan, Guaranty and Security Agreement dated as of February 2, 2007 (the “Loan Agreement”). 
 B. Borrower has requested that Agent and Lenders consent to an amendment of the Loan Agreement on the terms set forth herein. 
 C. Agent and Lenders are willing to enter into this Agreement to consent to such transactions, upon the terms and conditions set forth below. 
 NOW THEREFORE, in consideration of the matters set forth in the recitals and the covenants and provisions herein set forth, and other valuable
consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto agree as follows: 
 1. Amendments.

 (a) Section 1.1 of the Loan Agreement is hereby amended by adding the following new definition thereto in appropriate
alphabetical order: 
 “Securities Account Availability Agreement” means that certain Securities Account
Availability Agreement dated as of March 18, 2009 by and among the Agent and the Borrower (as the same may be amended, restated or otherwise modified from time to time). 
 (b) Section 1.1 of the Loan Agreement is hereby amended by adding the phrase “the Securities Account Availability Agreement,”
between the phrases “Letter of Credit,” and “Officers’ Certificate” where the same appear in the definition of “Loan Documents” in such Section. 
 (c) Section 2.1(a) of the Loan Agreement is hereby amended by adding the following language immediately at the end thereof: 
 “Notwithstanding the foregoing, so long as there is at least $2,000,000 in the USBNA Accounts (as defined in the Securities Account
Availability Agreement) subject to the Agent’s perfected first priority lien, Agent and Lenders hereby agree, subject to the other conditions to borrowing hereunder being met, to make available up to an additional $1,000,000 in Advances in the
aggregate pursuant to this Section 2.1(a) (provided that in no event shall outstanding Advances exceed the Maximum Revolver Amount less the Letter of Credit Usage less outstanding Advances).” 

 3. Representations and Warranties. To induce Agent and Lenders to enter into this
Agreement, Borrower represents and warrants to Agent and the Lenders that the execution, delivery and performance is within its corporate powers, as applicable, has been duly authorized by all necessary corporate action, and does not and will not
contravene or conflict with any provision of law applicable to Borrower, the Certificate of Incorporation, or Bylaws, of Borrower, or any order, judgment or decree of any court or other agency of government or any contractual obligation binding upon
Borrower; and the Loan Agreement as of the date hereof is the legal, valid and binding obligation of Borrower enforceable against such Person in accordance with its terms, subject to bankruptcy, insolvency, moratorium and similar laws affecting the
enforceability of creditors’ rights generally and to general principals of equity. Borrower hereby further represents and warrants that its warranties and representations contained in the Loan Agreement and the other Loan Documents are true and
correct both before and after the Effective Date (both before and after giving effect to the transactions contemplated hereby) with the same effect as though made on such date (except to the extent stated to relate to an earlier date, in which case
such representations and warranties were true and correct as of such earlier date). 
 4. Conditions. The effectiveness of the
consents stated in this Agreement is subject to each of the following conditions precedent (the date of consummation of which shall be the “Effective Date”): 
 (A) Agreement. Agent shall have received counterparts of this Agreement duly executed by Borrower, Agent and each Lender.

 (B) No Default. After giving effect to this Agreement, no Default or Event of Default under the Loan Agreement shall
have occurred and be continuing. 
 (C) Securities Account Availability Agreement. The Securities Account Availability
Agreement shall have been executed by the Borrower and Agent and shall be in full force and effect. 
 (D) Warranties and
Representations. The warranties and representations of Borrower contained in this Agreement, the Loan Agreement and the other Loan Documents, shall each be true and correct as of the effective date hereof, with the same effect as though made on
such date (except to the extent expressly stated to relate to an earlier date, in which case such representations and warranties were true and correct as of such earlier date). 
 (E) Additional Deliveries. Borrower shall have executed and delivered such additional certificates and documents as Agent may
require in connection with the transactions contemplated by this Agreement. 
 5. Miscellaneous. 
 (A) Captions. Section captions used in this Agreement are for convenience only, and shall not affect the construction of this
Agreement. 
 (B) Governing Law. This Agreement shall be governed by and shall be construed and enforced in accordance
with the internal laws of the State of New York, without regard to conflict of laws principles. 
 (C) Counterparts.
This Agreement may be executed in any number of counterparts, and each such counterpart shall be deemed to be an original, but all such counterparts shall together constitute but one and the same Agreement. Delivery of an executed signature page to
this Agreement by telecopy shall be deemed to constitute delivery of an originally executed signature page hereto. 
 (D)
Successors and Assigns. This Agreement shall be binding upon and inure to the benefit of the parties hereto and their respective successors and assigns. 
  

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 (E) References. Any reference to the Loan Agreement contained in any notice,
request, certificate, or other document executed concurrently with or after the execution and delivery of this Agreement shall be deemed to include this Agreement unless the context shall otherwise require. 
 (F) Payment of Expenses. Borrower agrees to pay all reasonable out of pocket expenses (including reasonable attorney’s fees)
of Agent in connection with the preparation and execution of this Agreement. 
 [Signature Pages Follow] 
  

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 Witness the due execution hereof by the respective duly authorized officers of the undersigned as of the
date first above written. 
  

			
	DESIGN WITHIN REACH, INC.
		
	By:	 	/s/ Theodore R. Upland III
	Name:	 	Theodore R. Upland III
	Title:	 	Chief Financial Officer

  

			
	WELLS FARGO RETAIL FINANCE, LLC,
as Agent and a Lender
		
	By:	 	/s/ Joseph Burt
	Name:	 	Joseph Burt
	Title:	 	Vice President

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