Document:

EX-4.3

 Exhibit 4.3 

AMERICAN HOMES 4 RENT, L.P., 
 AS
ISSUER, 
 AND 
 U.S. BANK
NATIONAL ASSOCIATION, 
 AS TRUSTEE 

FOURTH SUPPLEMENTAL INDENTURE 

Dated as of July 8, 2021 

$300,000,000 3.375% SENIOR NOTES DUE 2051 

SUPPLEMENT TO INDENTURE 
 DATED AS
OF FEBRUARY 7, 2018, BETWEEN 
 AMERICAN HOMES 4 RENT, L.P., AS ISSUER, 

AND 
 U.S. BANK NATIONAL
ASSOCIATION, AS TRUSTEE 

 FOURTH SUPPLEMENTAL INDENTURE, dated as of July 8, 2021 (this “Fourth
Supplemental Indenture”), between AMERICAN HOMES 4 RENT, L.P., a Delaware limited partnership (the “Operating Partnership”), having its principal executive office located at 23975 Park Sorrento, Suite 300, Calabasas,
California 91302, and U.S. BANK NATIONAL ASSOCIATION, a national banking association organized and existing under the laws of the United States, as trustee (the “Trustee”), which supplements that certain Indenture, dated as of
February 7, 2018, by and between the Operating Partnership and the Trustee (the “Base Indenture,” and together with this Fourth Supplemental Indenture, the “Indenture”). 

RECITALS 
 WHEREAS, the
Operating Partnership has duly authorized the execution and delivery of the Base Indenture to the Trustee to provide for the issuance from time to time for its lawful purposes of debt securities evidencing the Operating Partnership’s
debentures, notes or other evidences of indebtedness. 
 WHEREAS, Section 301 of the Base Indenture provides that by means of a
supplemental indenture the Operating Partnership may create one or more series of the Operating Partnership’s debt securities and establish the form, terms and provisions thereof. 

WHEREAS, the Operating Partnership intends by this Fourth Supplemental Indenture to (i) create a series of the Operating
Partnership’s debt securities, in an initial aggregate principal amount equal to $300,000,000, entitled “3.375% Senior Notes due 2051” (the “Notes”) and (ii) establish the form and the terms and provisions of the
Notes. 
 WHEREAS, the consent of Holders to the execution and delivery of this Fourth Supplemental Indenture is not required, and all other
actions required to be taken under the Base Indenture with respect to this Fourth Supplemental Indenture have been taken. 
 NOW, THEREFORE
IT IS AGREED: 
 ARTICLE ONE 

DEFINITIONS, CREATION, FORM AND TERMS AND CONDITIONS OF THE DEBT SECURITIES 

Section 1.1    Definitions. Capitalized terms used but not otherwise defined in this Fourth Supplemental
Indenture shall have the meanings ascribed to them in the Base Indenture. In addition, the following terms shall have the following meanings to be equally applicable to both the singular and the plural forms of the terms set forth below: 

“Company” means American Homes 4 Rent, a Maryland real estate investment trust. 

“Consolidated Income Available for Debt Service” means, for any period of time, the Operating Partnership’s Consolidated
Net Income for such period, plus amounts which have been deducted and minus amounts which have been added for such period, without duplication: (a) Interest Expense on Indebtedness; (b) provision for taxes based on income;
(c) depreciation, amortization and all other non-cash items deducted at arriving at Consolidated Net Income and premium and deferred financing costs; (d) provision for gains, losses or impairments on
sales or other dispositions of properties and other investments; (e) extraordinary and non-recurring items, as the Operating Partnership determined in good faith; and
(f) non-controlling interests (other than with respect to cash dividends and distributions actually received and included in the definition of “Consolidated Net Income” as set forth below). In
each case for such period, the Operating Partnership will reasonably determine amounts in accordance with GAAP, except to the extent GAAP is not applicable with respect to the determination of non-cash and non-recurring items. 
 “Consolidated Net Income” means, for any period of time, the
amount of net income, or loss, for the Operating Partnership and its Consolidated Subsidiaries for such period, excluding, net income (or losses) attributable to non-controlling interests in unconsolidated
Persons except to the extent of cash dividends and 

  
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distributions actually received by the Operating Partnership or one of its Consolidated Subsidiaries during such period, all determined in accordance with GAAP. 

“Consolidated Financial Statements” means, with respect to any Person, collectively, the consolidated financial statements
and notes to those financial statements of that Person and its consolidated subsidiaries prepared in accordance with GAAP. 

“Consolidated Subsidiary” means each Subsidiary of the Operating Partnership that is consolidated in its Consolidated
Financial Statements. 
 “Credit Agreement” means the Amended and Restated Credit Agreement, dated April 15, 2021, by
and among the Operating Partnership, as borrower, the Company, as parent, Wells Fargo Bank, National Association, as administrative agent, and the other lending institutions that are parties thereto, as lenders, as it may be amended, supplemented,
modified, extended, restructured, renewed, refinanced, restated, refunded or replaced (in whole or in part, including with any new credit agreement or facility) from time to time. 

“Depository” means The Depository Trust Company or any successor securities clearing agency. 

“GAAP” means generally accepted accounting principles in the United States of America as in effect on the date of any
required calculation or determination. 
 “Incur” means, with respect to any Indebtedness or other obligation of any
Person, to create, assume, guarantee or otherwise become liable in respect of the Indebtedness or other obligation, and “Incurrence” and “Incurred” have meanings correlative to the foregoing. Indebtedness or other obligation of
the Operating Partnership or any Subsidiary of the Operating Partnership will be deemed to be Incurred by the Operating Partnership or such Subsidiary whenever the Operating Partnership or such Subsidiary shall create, assume, guarantee or otherwise
become liable in respect thereof. Indebtedness or other obligation of a Subsidiary of the Operating Partnership existing prior to the time it became a Subsidiary of the Operating Partnership will be deemed to be Incurred upon such Subsidiary
becoming a Subsidiary of the Operating Partnership; and Indebtedness or other obligation of a Person existing prior to a merger or consolidation of such Person with the Operating Partnership or any Subsidiary of the Operating Partnership in which
such Person is the successor to the Operating Partnership or such Subsidiary will be deemed to be Incurred upon the consummation of such merger or consolidation. Any issuance or transfer of capital stock that results in Indebtedness constituting
Intercompany Indebtedness being held by a Person other than the Operating Partnership, the Company or any Consolidated Subsidiary or any sale or other transfer of any Indebtedness constituting Intercompany Indebtedness to a Person that is not the
Operating Partnership, the Company or any Consolidated Subsidiary, will be deemed, in each case, to be an Incurrence of Indebtedness that is not Intercompany Indebtedness at the time of such issuance, transfer or sale, as the case may be. 

“Indebtedness,” of the Operating Partnership or any Consolidated Subsidiary means, without duplication, any of the Operating
Partnership’s indebtedness or that of any Consolidated Subsidiary, whether or not contingent, in respect of: (a) borrowed money evidenced by bonds, notes, debentures or similar instruments whether or not such indebtedness is secured by any
lien existing on property owned by the Operating Partnership or any Consolidated Subsidiary; (b) indebtedness for borrowed money of a Person other than the Operating Partnership or a Consolidated Subsidiary which is secured by any lien on
property or other asset owned by the Operating Partnership or any Consolidated Subsidiary, to the extent of the lesser of (i) the amount of indebtedness so secured, and (ii) the fair market value (determined in good faith by the Operating
Partnership) of the property subject to such lien; (c) reimbursement obligations, contingent or otherwise, in connection with any letters of credit actually issued; or (d) any lease of property by the Operating Partnership or any
Consolidated Subsidiary as lessee which is reflected on the Operating Partnership’s consolidated balance sheet as a finance lease in accordance with GAAP; to the extent, in the case of indebtedness under (a) through (c) above, that any
such items (other than letters of credit) would appear as a liability on the Operating Partnership’s consolidated balance sheet in accordance with GAAP. Indebtedness also (1) includes, to the extent not otherwise included, any non-contingent obligation by the Operating Partnership or any Consolidated Subsidiary to be liable for, or to pay, as obligor, guarantor or otherwise (other than for purposes of collection in the ordinary course of
business), indebtedness of another Person (other than the Operating Partnership or any Consolidated Subsidiary) of the type described in clauses (a)-(d) of this definition, other than obligations to be liable for the Indebtedness of another Person
solely as a result of customary exceptions to non-

  
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recourse indebtedness, such as for fraud, misapplication of funds, environmental indemnities, voluntary bankruptcy, collusive involuntary bankruptcy and other similar exceptions, and
(2) excludes, any such indebtedness (or obligation referenced in clause (1) above) that has been the subject of an “in substance” defeasance in accordance with GAAP. 

“Intercompany Indebtedness” means Indebtedness to which the only parties are any of the Operating Partnership and any
Consolidated Subsidiary; provided, however, that with respect to any such Indebtedness of which the Operating Partnership or any Guarantor is the borrower or issuer, such Indebtedness is subordinate in right of payment to the Notes.

 “Interest Expense” means, for any period of time, the interest expense of, the Operating Partnership and its
Subsidiaries’ Indebtedness, determined on a consolidated basis in accordance with GAAP, but excluding: (i) interest reserves funded from the proceeds of any loan; (ii) amortization of deferred financing costs, including gains or
losses on early extinguishment of debt; (iii) prepayment penalties; (iv) non-cash swap ineffectiveness charges; and (v) any expenses resulting from the discounting of any indebtedness in
connection with the application of purchase accounting in connection with any acquisition; and including, without duplication, effective interest in respect of original issue discount as determined in accordance with GAAP. 

“Make-Whole Amount” means the excess of (1) the net present value, on the Redemption Date, of the principal being
redeemed and the amount of interest (exclusive of interest accrued to the date of redemption) that would have been payable if such redemption had not been made (calculated as if the maturity date of the Notes was the Par Call Date), over
(2) the aggregate principal amount of the Notes being redeemed. Net present value shall be calculated by discounting, on a semi-annual basis, such principal and interest at the Reinvestment Rate (as determined on the third Business Day
preceding the date of the notice of redemption) from the respective dates on which such principal and interest would have been payable if such redemption had not been made, to the date of redemption. 

“Reinvestment Rate” means 0.25%, plus the weekly yield for the most recent week set forth in the most recent Statistical
Release (as defined below) for the constant maturity U.S. Treasury security (rounded to the nearest month) corresponding to the remaining life to maturity (assuming, for the purposes of this definition, that the Notes mature on the Par Call Date),
as of the payment date of the principal being redeemed. If no maturity exactly corresponds to such maturity, yields for the two published maturities most closely corresponding to such maturity shall be calculated pursuant to the immediately
preceding sentence and the Reinvestment Rate shall be interpolated or extrapolated from such yields on a straight-line basis, rounding in each of such relevant periods to the nearest month. For the purpose of calculating the Reinvestment Rate, the
most recent Statistical Release published prior to the date of determination of the Make-Whole Amount shall be used. If the format or content of the Statistical Release changes in a manner that precludes determination of the yield in the above
manner, then the yield will be determined in the manner that most closely approximates the above manner, as the Operating Partnership reasonably determine. 

“Reporting Date” means each fiscal quarter covered in the Operating Partnership’s annual or quarterly report most
recently furnished to Holders of the Notes or filed with the Commission, as the case may be. 
 “Secured Debt” means, as of
any date, that portion of principal amount of outstanding Indebtedness, excluding Intercompany Indebtedness, of the Operating Partnership and its Consolidated Subsidiaries as of that date that is secured by a mortgage, trust deed, deed of trust,
deeds to secure Indebtedness, pledge, security interest, assignment for collateral purposes, deposit arrangement, or other security agreement, excluding any right of setoff but including, without limitation, any conditional sale or other title
retention agreement, any financing lease having substantially the same economic effect as any of the foregoing, and any other like agreement granting or conveying a security interest. 

“Statistical Release” means the statistical release designated “H.15” or any successor publication that is
published weekly by the Federal Reserve System (or comparable online data source or publication) which establishes yields on actively traded U.S. government securities adjusted to constant maturities, or, if such Statistical Release is not published
at the time of any determination under the Indenture, then such other reasonably comparable index which shall be designated by the Operating Partnership. 

  
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 “Subsidiary” means (1) any corporation at least a majority of the
total voting power of whose outstanding Voting Stock is owned, directly or indirectly, at the date of determination by the Operating Partnership and/or one or more other Subsidiaries, and (2) any other Person in which the Operating Partnership,
and/or one or more other Subsidiaries, directly or indirectly, at the date of determination, (x) own at least a majority of the outstanding ownership interests or (y) have the power to elect or direct the election of, or to appoint or
approve the appointment of, at least a majority of the directors, trustees or managing members of, or other persons holding similar positions with, such Person. 

“Total Assets” means, as of any time, the sum of, without duplication, Undepreciated Real Estate Assets and all other assets,
excluding accounts receivable and non-real estate intangibles, of the Operating Partnership and its Consolidated Subsidiaries, all determined in accordance with GAAP. 

“Total Unencumbered Assets” means, as of any time, the sum of, without duplication, those Undepreciated Real Estate Assets
which are not subject to a lien securing Indebtedness and all other assets, excluding accounts receivable and non-real estate intangibles, of the Operating Partnership and its Consolidated Subsidiaries not
subject to a lien securing Indebtedness, all determined in accordance with GAAP; provided, however, that all investments by the Operating Partnership or its Consolidated Subsidiaries in unconsolidated joint ventures, unconsolidated
limited partnerships, unconsolidated limited liability companies and other unconsolidated entities shall be excluded from Total Unencumbered Assets to the extent that such investments would have otherwise been included for the purposes of
Section 2.1(c). 
 “Undepreciated Real Estate Assets” means, as of any time, the cost (original cost plus capital
improvements) of the Operating Partnership’s real estate assets, right of use assets associated with a finance lease in accordance with GAAP and related intangibles and the real estate assets and related intangibles of the Operating
Partnership’s Consolidated Subsidiaries on such date, before depreciation and amortization, all determined in accordance with GAAP; provided, however, that “Undepreciated Real Estate Assets” shall not include the right
of use assets associated with an operating lease in accordance with GAAP. 
 “Unsecured Debt” means that portion of the
outstanding principal amount of the Operating Partnership and its Consolidated Subsidiaries’ Indebtedness, excluding Intercompany Indebtedness, that is not Secured Debt. 

“Voting Stock” means, with respect to any Person, any class or series of capital stock of, or other equity interests in, such
Person the holders of which are ordinarily, in the absence of contingencies, entitled to vote for the election of, or to appoint or to approve the appointment of, the directors, trustees or managing members of, or other persons holding similar
positions with, such Person. 
 Section 1.2    Creation of the Notes. In accordance with Section 301 of
the Base Indenture, the Operating Partnership hereby creates the Notes as a separate series of its senior unsecured debt securities, entitled “3.375% Senior Notes due 2051”, issued pursuant to the Indenture. The Notes shall initially be
limited to an aggregate principal amount equal to $300,000,000, subject to the exceptions set forth in Section 301(2) of the Base Indenture and Section 1.4(f) hereof. 

Section 1.3    Form of the Notes. The Notes will be issued in the form of one or more permanent fully
registered global securities (the “Global Note”) that will be deposited with, or on behalf of the Depository, and registered in the name of the Depository or its nominee, as the case may be, subject to Section 305 of the Base
Indenture. So long as the Depository, or its nominee, is the registered owner of the Global Note, the Depository or its nominee, as the case may be, will be considered the sole Holder of the Notes represented by the Global Note for all purposes
under the Indenture. 
 Section 1.4    Terms and Provisions of the Notes. The Notes shall be governed by all
of the terms and provisions of the Base Indenture, as supplemented and amended by this Fourth Supplemental Indenture, and in particular, the following provisions shall be terms of the Notes: 

(a)    Registration and Form. The Notes shall be issuable in registered form without coupons in minimum
denominations of $2,000 and integral multiples of $1,000 in excess thereof. Each Note shall be dated the 

  
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date of its authentication and shall be substantially in the form of Exhibit A attached hereto. The Operating Partnership, any Guarantor, the Trustee and any agent of the Operating Partnership,
any Guarantor or the Trustee shall treat the Person in whose name a Note is registered in the Security Register as the owner of such Note for all purposes whatsoever, and none of the Operating Partnership, any Guarantor, the Trustee or any agent of
the Operating Partnership, any Guarantor or the Trustee shall be affected by notice to the contrary. 

(b)    Payment of Principal and Interest. All payments of principal, Make-Whole Amount, if any, and interest in
respect of the Global Notes will be made by the Operating Partnership in immediately available funds to the Depository or its nominee, as the case may be, as the Holder of each of the Global Notes. The Notes shall mature, and the unpaid principal
thereon, shall be payable, on July 15, 2051, subject to the provisions of the Base Indenture. The rate per annum at which interest shall be payable on the Notes shall be 3.375%. Interest on the Notes will be payable semi-annually in arrears on
each January 15 and July 15, commencing January 15, 2022 (each, an “Interest Payment Date”) and on the Stated Maturity as specified in this Section 1.4(b), to the Persons in whose names the Notes are registered
in the Security Register applicable to the Notes at the close of business on January 1 for Interest Payment Dates of January 15 and July 1 for Interest Payment Dates of July 15 (in each case, whether or not a Business Day) (each,
a “Record Date”). Interest on the Notes shall be computed on the basis of a 360-day year consisting of twelve 30-day months. Interest on the Notes shall
accrue from July 8, 2021. 
 (c)    Sinking Fund. There shall be no sinking fund provided for the Notes.

 (d)    Redemption at the Option of the Operating Partnership. 

(1)    The Operating Partnership shall have the right to redeem the Notes at its option and in its sole discretion in
whole at any time or in part from time to time, (x) prior to January 15, 2051 (the “Par Call Date”), at a Redemption Price equal to the sum of: (1) 100% of the principal amount being redeemed, plus accrued and unpaid
interest thereon to, but not including, the Redemption Date; and (2) the Make-Whole Amount, if any, and (y) on or after the Par Call Date, at a Redemption Price equal to 100% of the principal amount of the Notes being redeemed plus accrued
and unpaid interest thereon to, but not including, the Redemption Date. 
 (2)    The Operating Partnership shall not
redeem the Notes pursuant to Section 1.4(d)(1) hereof on any date if the principal amount of the Notes has been accelerated, and such acceleration has not been rescinded or annulled on or prior to such date (except in the case of an
acceleration resulting from a default by the Operating Partnership in the payment of the Redemption Price with respect to the Notes to be redeemed). 

(e)    Payment of Notes Called for Redemption by the Operating Partnership. 

(1)    If notice of redemption has been given as provided in Article Eleven of the Base Indenture, the Notes or portion of
Notes with respect to which such notice has been given shall become irrevocably due and payable on the Redemption Date and at the place or places stated in such notice at the Redemption Price, and unless the Operating Partnership shall default in
the payment of the Redemption Price, so long as the Paying Agent holds funds irrevocably deposited with it sufficient to pay the Redemption Price of the Notes to be redeemed on the Redemption Date, then (a) such Notes will cease to be
Outstanding on and after the date of the deposit, (b) interest on the Notes or portion of Notes so called for redemption shall cease to accrue on and after the Redemption Date, and (c) the Holders of the Notes being redeemed shall have no
right in respect of such Notes except the right to receive the Redemption Price thereof. On surrender of such Notes at the place of payment specified in such notice of redemption, the said Notes or the specified portions thereof shall be paid and
redeemed by the Operating Partnership at the Redemption Price. 
 (2)    The Notes will not be convertible or
exchangeable for any other security or property. 
 (f)    Additional Issues. The Operating Partnership may, from
time to time, without notice to or the consent of the Holders of the Notes, increase the principal amount of the Notes by issuing additional debt securities, in which case any additional debt securities so issued will have the same form and terms
(other than the date of issuance and, under certain circumstances, the public offering price and the date from which interest thereon will begin to accrue), and will carry the same right to receive accrued and unpaid interest, as the Notes.
Additional debt 

  
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securities issued in this manner will be consolidated with, and form a single series of debt securities with, the Notes; provided, however, that such additional debt securities will not be
issued with the same CUSIP number as the Notes unless such additional debt securities are treated as part of the same issue as the Notes for U.S. federal income tax purposes. 

(g)    Other. The public offering price of the Notes issued on the date hereof was 97.962% of par value. 

Section 1.5    Book-Entry Provisions. This Section 1.5 shall apply only to the Global Notes deposited
with or on behalf of the Depository. 
 (a)    The Operating Partnership shall execute and the Trustee shall, in
accordance with this Section 1.5 and Section 303 of the Base Indenture, authenticate and deliver the Global Notes that shall be registered in the name of the Depository or its nominee and shall be held by the Trustee as custodian for the
Depository. 
 (b)    Participants of the Depository shall have no rights either under the Indenture or with respect to
the Global Notes. The Depository or its nominee, as applicable, shall be treated by the Operating Partnership, the Trustee and any agent of the Operating Partnership or the Trustee as the absolute owner and Holder of each such Global Note for all
purposes under the Indenture. Notwithstanding the foregoing, nothing herein shall prevent the Operating Partnership or the Trustee from giving effect to any written certification, proxy or other authorization furnished by the Depository or its
nominee, as applicable, or impair, as between the Depository and its participants, the operation of customary practices of such Depository governing the exercise of the rights of an owner of a beneficial interest in the Global Notes. 

ARTICLE TWO 
 ADDITIONAL
COVENANTS FOR THE BENEFIT OF HOLDERS OF NOTES 
 In addition to the covenants set forth in the Base Indenture, the Operating Partnership
hereby further covenants as follows, the following covenants being for the sole benefit of the Holders of the Notes: 

Section 2.1    Negative Covenants. 

(a)    Limitation on Indebtedness. The Operating Partnership will not, and will not permit any of its Subsidiaries
to, Incur any Indebtedness, other than Intercompany Indebtedness and guarantees of Indebtedness Incurred by the Operating Partnership or any of its Subsidiaries in compliance with the Indenture, if, immediately after giving effect to the Incurrence
of such Indebtedness and the application of the proceeds thereof, the aggregate principal amount of the Operating Partnership and its Consolidated Subsidiaries’ outstanding Indebtedness, excluding Intercompany Indebtedness, would be greater
than 60% of the sum of, without duplication: (1) Total Assets as of the end of the most recent Reporting Date; and (2) the aggregate purchase price of any assets acquired, and the aggregate amount of any debt or securities offering
proceeds received (to the extent that such proceeds were not used to acquire assets or used to reduce Indebtedness), by the Operating Partnership or any of its Subsidiaries since the end of the most recent Reporting Date, including those proceeds
obtained in connection with the Incurrence of such additional Indebtedness. 
 (b)    Limitation on Secured Debt.
The Operating Partnership will not, and will not permit any of its Subsidiaries to, Incur any Secured Debt, other than Intercompany Indebtedness and guarantees of Secured Debt Incurred by the Operating Partnership or any of its Subsidiaries in
compliance with the Indenture, if, immediately after giving effect to the Incurrence of such Secured Debt and the application of the proceeds thereof, the aggregate principal amount of Secured Debt would be greater than 40% of the sum of, without
duplication: (1) Total Assets as of the end of the most recent Reporting Date; and (2) the aggregate purchase price of any assets acquired, and the aggregate amount of any debt or securities offering proceeds received (to the extent that
such proceeds were not used to acquire assets or used to reduce Indebtedness), by the Operating Partnership or any of its Subsidiaries since the end of the most recent Reporting Date, including those proceeds obtained in connection with the
Incurrence of such additional Secured Indebtedness. 

  
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 (c)    Maintenance of Unencumbered Assets. The Operating
Partnership will have at all times Total Unencumbered Assets of not less than 150% of the aggregate principal amount of all of the Operating Partnership and its Subsidiaries’ outstanding total Unsecured Debt, determined on a consolidated basis
in accordance with GAAP. 
 (d)    Debt Service Ratio. The Operating Partnership will not permit the ratio of
Consolidated Income Available for Debt Service to Interest Expense for the period consisting of the four consecutive fiscal quarters ended on the most recent Reporting Date to be less than 1.5:1 as of such Reporting Date. 

Section 2.2    Guarantees. 

(a)    Future Guarantors. If on or after the date of this Fourth Supplemental Indenture, the Company or any
Subsidiary of the Operating Partnership guarantees the Operating Partnership’s indebtedness under, or otherwise becomes an obligor with respect to, the Credit Agreement (if the Company or such Subsidiary, as the case may be, is not already a
Guarantor of the Notes), such entity (each, a “Possible Future Guarantor”) shall immediately be and become, automatically and without the execution or delivery of any supplemental indenture or other instrument or other action by any
Person, jointly and severally with any other Guarantors of the Notes, a Guarantor of the Notes and shall be subject to and bound by all of the terms and provisions of the Indenture applicable to a Guarantor of the Notes (subject to
Section 2.2(b)); provided that the Operating Partnership shall cause such Possible Future Guarantor to within thirty (30) calendar days, (i) execute and deliver to the Trustee a supplemental indenture substantially in the form
of Exhibit B to acknowledge such Guarantee in accordance with this Section 2.2 and Article Sixteen of the Indenture, and (ii) deliver to the Trustee, in addition to any other documents to be delivered to the Trustee pursuant to
Section 903 of the Base Indenture, an Opinion of Counsel to the effect that (x) the execution of such supplemental indenture is authorized or permitted by the Base Indenture, and (y) such supplemental indenture, has been duly
authorized, executed and delivered by, and is a valid and binding obligation of such entity, enforceable against such entity in accordance with its terms, subject to customary exceptions. For so long as any Possible Future Guarantor provides a
Guarantee, such Possible Future Guarantor shall agree that it waives and will not in any manner whatsoever claim or take the benefit or advantage of any right of reimbursement, indemnity or subrogation or any other rights against the Operating
Partnership as a result of any payment by it under its guarantee until the Notes have been paid in full. 

(b)    Release of Guarantee. The Guarantee of any Guarantor shall automatically and unconditionally terminate and
be released and the Indenture and any supplemental indenture, to the extent relating thereto, shall no longer have any effect, upon: (i) such Guarantor no longer guaranteeing or otherwise being an obligor with respect to the Credit Agreement;
provided that the foregoing provisions of this clause (i) and any release of such Guarantor’s Guarantee pursuant to this clause (i) shall not limit the obligation of such Guarantor to guarantee the Notes at any time thereafter
pursuant to this Section 2.2; or (ii) legal defeasance, covenant defeasance or discharge of the Notes, as provided under Article Four of the Base Indenture. 

Section 2.3    Covenant Defeasance and Waiver of Covenant. The covenants set forth in Sections 2.1 and 2.2
shall be subject to covenant defeasance under Section 402(3) of the Base Indenture and subject to waiver under Section 1006 thereof. 

ARTICLE THREE 

ADDITIONAL AMENDMENTS 

Section 3.1    Events of Default. Section 3.1(a) shall replace Section 501(5) of the Base Indenture
with respect to the Notes only. 
 (a)    failure to pay any recourse indebtedness for monies borrowed by the Operating
Partnership in an outstanding principal amount in excess of $50,000,000 at final maturity or upon acceleration after the expiration of any applicable notice and grace period, which recourse indebtedness is not discharged, or such default in payment
or acceleration is not cured or rescinded, within thirty (30) calendar days after written notice to the Operating Partnership from the Trustee (or to the Operating Partnership and the Trustee from Holders of at least twenty five percent (25%)
in aggregate principal amount of the Notes then outstanding); 

  
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 ARTICLE FOUR 

TRUSTEE 

Section 4.1    Trustee. The Trustee is appointed as the principal paying agent, transfer agent and registrar
for the Notes and for the purposes of Section 1002 of the Base Indenture. The Notes may be presented for payment at the Corporate Trust Office of the Trustee or at any other agency as may be appointed from time to time by the Operating
Partnership in the United States of America (or otherwise in accordance with applicable procedures of DTC in the case of global notes). The Trustee shall not be responsible in any manner whatsoever for or in respect of the validity or sufficiency of
this Fourth Supplemental Indenture or the due execution hereof by the Operating Partnership. The recitals of fact contained herein shall be taken as the statements solely of the Operating Partnership and the Trustee assumes no responsibility for the
correctness thereof. 
 Section 4.2    Preferential Collection of Claims. If the Trustee shall be or become
a creditor of the Operating Partnership (or any other obligor upon the Notes), the Trustee shall be subject to the provisions of the Trust Indenture Act regarding the collection of the claims against the Operating Partnership (or any such other
obligor). The Trustee is permitted to engage in other transactions with the Operating Partnership and its Affiliates. If, however, it acquires any conflicting interest under the Trust Indenture Act relating to any of its duties with respect to the
Notes, it must eliminate that conflict or resign, subject to its right under the Trust Indenture Act to seek a stay of its duty to resign. 

Section 4.3    Calculation with Respect to the Notes. The Operating Partnership shall be responsible for
making all calculations required under this Fourth Supplemental Indenture or with respect to the Notes. The Operating Partnership will make such calculations in good faith and, absent manifest error, the Operating Partnership’s calculations
will be final and binding on the Trustee and the Holders of the Notes. The Operating Partnership shall provide a schedule of its calculations to the Trustee promptly after it makes such calculations, and the Trustee shall be entitled to rely upon
the accuracy of the Operating Partnership’s calculations without independent verification. The Trustee shall forward the Operating Partnership’s calculations to any Holder of the Notes upon request. 

Section 4.4    Additional Provisions Concerning the Trustee. U.S. Bank National Association is acting under
this Fourth Supplemental Indenture solely in its capacity as Trustee under the Base Indenture and not in its individual capacity. In acting hereunder, the Trustee shall be entitled to all of the rights, privileges and immunities granted to it under
the Base Indenture, as if such rights, privileges and immunities were set forth herein. 
 ARTICLE FIVE 

MISCELLANEOUS PROVISIONS 

Section 5.1    Ratification of Base Indenture. This Fourth Supplemental Indenture is executed and shall be
construed as an indenture supplemental to the Base Indenture, and as supplemented and modified hereby, the Base Indenture is in all respects ratified and confirmed, and the Base Indenture and this Fourth Supplemental Indenture shall be read, taken
and construed as one and the same instrument. In the event of a conflict between the language of this Fourth Supplemental Indenture and the Base Indenture, the language of this Fourth Supplemental Indenture shall control. 

Section 5.2    Effect of Headings. The Article and Section headings herein are for convenience only and shall
not affect the construction hereof. 
 Section 5.3    Successors and Assigns. All covenants and agreements
in this Fourth Supplemental Indenture by the Operating Partnership shall bind its successors and assigns, whether so expressed or not. 

Section 5.4    Separability Clause. In case any one or more of the provisions contained in this Fourth
Supplemental Indenture shall for any reason be held to be invalid, illegal or unenforceable in any respect, the validity, legality and enforceability of the remaining provisions shall not in any way be affected or impaired thereby. 

  
 9 

 Section 5.5    GOVERNING LAW. THIS FOURTH
SUPPLEMENTAL INDENTURE SHALL BE GOVERNED BY, AND CONSTRUED IN ACCORDANCE WITH, THE LAWS OF THE STATE OF NEW YORK. THIS FOURTH SUPPLEMENTAL INDENTURE IS SUBJECT TO THE PROVISIONS OF THE TRUST INDENTURE ACT, THAT ARE REQUIRED TO
BE PART OF THIS FOURTH SUPPLEMENTAL INDENTURE AND SHALL, TO THE EXTENT APPLICABLE, BE GOVERNED BY SUCH PROVISIONS. 

Section 5.6    Counterparts. This Fourth Supplemental Indenture may be executed in several counterparts, each
of which shall be an original and all of which shall constitute one and the same instrument. The exchange of copies of this Fourth Supplemental Indenture and of signature pages by facsimile or PDF transmission shall constitute effective execution
and delivery of this Fourth Supplemental Indenture as to the parties hereto and may be used in lieu of the original Fourth Supplemental Indenture and signature pages for all purposes. Signatures of the parties hereto transmitted by facsimile or PDF
shall be deemed to be their original signatures for all purposes. All notices, approvals, consents, requests and any communications hereunder must be in writing (provided that any such communication sent to the Trustee hereunder must be in the form
of a document that is signed manually or by way of a digital signature provided by DocuSign (or such other digital signature provider as specified in writing to the Trustee by the authorized representative), in English. The Operating
Partnership agrees to assume all risks arising out of the use of using digital signatures and electronic methods to submit communications to the Trustee, including without limitation the risk of the Trustee acting on unauthorized instructions, and
the risk of interception and misuse by third parties. 

  
 10 

 IN WITNESS WHEREOF, the parties hereto have caused this Fourth Supplemental Indenture to be
duly executed all as of the day and year first above written. 
  

					
	AMERICAN HOMES 4 RENT, L.P.
		
	By:	 	American Homes 4 Rent, its general partner
		
	By:	 	 /s/ Christopher C. Lau

		 	Name:	 	Christopher C. Lau
		 	Title:	 	Chief Financial Officer

  
 11 

 
					
	U.S. BANK NATIONAL ASSOCIATION,
	as Trustee
		
	By:	 	 /s/ Bradley E. Scarbrough

		 	Name:	 	Bradley E. Scarbrough
		 	Title:	 	Vice President

  
 12 

 EXHIBIT A 

Form of 3.375% Senior Notes due 2051 
 THIS
GLOBAL NOTE IS HELD BY OR ON BEHALF OF THE DEPOSITORY (AS DEFINED IN THE FOURTH SUPPLEMENTAL INDENTURE GOVERNING THIS NOTE) OR ITS NOMINEE IN CUSTODY FOR THE BENEFIT OF THE BENEFICIAL OWNERS HEREOF, AND IS NOT TRANSFERABLE TO ANY PERSON UNDER ANY
CIRCUMSTANCES EXCEPT THAT (1) THE TRUSTEE MAY MAKE SUCH NOTATIONS HEREON AS MAY BE REQUIRED PURSUANT TO SECTION 305 OF THE BASE INDENTURE, (2) THIS GLOBAL NOTE MAY BE EXCHANGED IN WHOLE BUT NOT IN PART PURSUANT TO SECTION 305 OF THE BASE
INDENTURE, (3) THIS GLOBAL NOTE MAY BE DELIVERED TO THE TRUSTEE FOR CANCELLATION PURSUANT TO SECTION 309 OF THE BASE INDENTURE AND (4) THIS GLOBAL NOTE MAY BE TRANSFERRED TO A SUCCESSOR DEPOSITORY WITH THE PRIOR WRITTEN CONSENT OF THE
ISSUER. 
 UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR NOTES IN DEFINITIVE FORM, THIS NOTE MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE
DEPOSITORY TO A NOMINEE OF THE DEPOSITORY OR BY A NOMINEE OF THE DEPOSITORY TO THE DEPOSITORY OR ANOTHER NOMINEE OF THE DEPOSITORY OR BY THE DEPOSITORY OR ANY SUCH NOMINEE TO A SUCCESSOR DEPOSITORY OR A NOMINEE OF SUCH SUCCESSOR DEPOSITORY. UNLESS
THIS CERTIFICATE IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY (55 WATER STREET, NEW YORK, NEW YORK) (“DTC”), TO THE ISSUER OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE
ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR SUCH OTHER NAME AS MAY BE REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC (AND ANY PAYMENT IS MADE TO CEDE & CO. OR SUCH OTHER ENTITY AS MAY BE REQUESTED BY AN AUTHORIZED
REPRESENTATIVE OF DTC), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL INASMUCH AS THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN. 

 AMERICAN HOMES 4 RENT, L.P. 

3.375% SENIOR NOTES DUE 2051 
  

			
	No. [●]	  	
	CUSIP No.:	  	02666T AD9
	ISIN:	  	US02666TAD90

 $[●] 

AMERICAN HOMES 4 RENT, L.P., a Delaware limited partnership (herein called the “Operating Partnership,” which term includes any successor
entity under the Indenture referred to on the reverse hereof), for value received hereby promises to pay to [Cede & Co.]*, or its registered assigns, the principal sum of [●]
($[●]), [or such lesser amount as is set forth in the Schedule of Increases or Decreases In the Global Note on the other side of this Note]*, on July 15, 2051 at the office or agency of the Operating Partnership maintained for that
purpose in accordance with the terms of the Indenture, in such coin or currency of the United States of America as at the time of payment shall be legal tender for the payment of public and private debts, and to pay interest, semi-annually on
January 15 and July 15 of each year, commencing January 15, 2022 on said principal sum at said office or agency, in like coin or currency, at the rate per annum of 3.375%, from the January 15 or July 15, as the case may be,
next preceding such Interest Payment Date to which interest has been paid or duly provided for, unless no interest has been paid or duly provided for on the Notes, in which case from July 8, 2021 until payment of said principal sum has been
paid or duly provided for. Unless otherwise provided in or pursuant to the Indenture, at the option of the Operating Partnership, interest on the Notes due and payable on any Interest Payment Date may be paid by mailing a check to the address of the
Person entitled thereto as such Person’s name and address shall appear in the Security Register or by transfer to an account maintained by such Person with a bank located in the United States of America. Any such interest which is punctually
paid or duly provided for on any Interest Payment Date shall be paid to the Person in whose name this Note (or one or more Predecessor Securities) is registered in the Security Register as of the close of business on the January 1 or
July 1 (whether or not a Business Day) next preceding such Interest Payment Date. 
 Reference is made to the further provisions of this Note set forth
on the reverse hereof and the Indenture governing this Note. Such further provisions shall for all purposes have the same effect as though fully set forth at this place. In the event of a conflict between the terms of this Note and the terms of the
Indenture, the terms of the Indenture shall control. 
 This Note shall not be valid or become obligatory for any purpose until the certificate of
authentication hereon shall have been signed manually by the Trustee or a duly authorized authenticating agent under the Indenture. 
  

 

	*	 Include only if the Note is issued in global form. 

  
 A-2 

 IN WITNESS WHEREOF, the Operating Partnership has caused this Note to be duly executed. 

Dated: [●] 
  

					
	AMERICAN HOMES 4 RENT, L.P.
		
	By:	 	American Homes 4 Rent, its general partner
			
		 	By:	 	
                     
                                        

		 		 	Name:
		 		 	Title:

  
 A-3 

 TRUSTEE’S CERTIFICATE OF AUTHENTICATION 

This is one of the Securities of the series designated therein referred to in the within-named Indenture. 

Dated: [●] 
  

			
	 U.S. BANK NATIONAL ASSOCIATION,
 as
Trustee

		
	By:	 	
                     
                    

		 	Name:
		 	Title:

  
 A-4 

 REVERSE SIDE OF NOTE 

AMERICAN HOMES 4 RENT, L.P. 

3.375% SENIOR NOTES DUE 2051 
 This Note is
one of a duly authorized issue of Notes of the Operating Partnership, designated as its 3.375% Senior Notes due 2051 (herein called the “Notes”), issued under and pursuant to an Indenture dated as of February 7, 2018 (herein
called the “Base Indenture”), between the Operating Partnership and U.S. Bank National Association, as trustee (herein called the “Trustee”), as supplemented by the Fourth Supplemental Indenture dated as of
July 8, 2021 (herein called the “Fourth Supplemental Indenture,” and together with the Base Indenture, the “Indenture”), between the Operating Partnership and the Trustee, to which Indenture and any indentures
supplemental thereto reference is hereby made for a description of the rights, limitations of rights, obligations, duties and immunities thereunder of the Trustee, the Operating Partnership and the Holders of the Notes. Defined terms used but not
otherwise defined in this Note shall have the respective meanings ascribed thereto in the Indenture. 
 The Operating Partnership shall have the right to
redeem the Notes at its option and in its sole discretion in whole at any time or in part from time to time, (x) prior to January 15, 2051 (the “Par Call Date”), at a Redemption Price equal to the sum of: (1) 100% of the
principal amount being redeemed, plus accrued and unpaid interest thereon to, but not including, the Redemption Date; and (2) the Make-Whole Amount, if any, and (y) on or after the Par Call Date, at a Redemption Price equal to 100% of the
principal amount of the Notes being redeemed plus accrued and unpaid interest thereon to, but not including, the Redemption Date. 
 The Operating
Partnership shall not redeem the Notes pursuant to Section 1.4(d)(1) of the Fourth Supplemental Indenture on any date if the principal amount of the Notes has been accelerated, and such acceleration has not been rescinded or annulled on or
prior to such date (except in the case of an acceleration resulting from a default by the Operating Partnership in the payment of the Redemption Price with respect to the Notes to be redeemed). 

If an Event of Default (other than an Event of Default specified in Section 501(6), 501(7) or 501(8) of the Base Indenture) occurs and is continuing, the
principal of, premium, if any, and accrued and unpaid interest on all the Notes may be declared to be due and payable immediately by either the Trustee or the Holders of at least twenty five percent (25%) in aggregate principal amount of the Notes
then outstanding, and, upon said declaration the same shall be immediately due and payable. If an Event of Default specified in Section 501(6), 501(7) or 501(8) of the Base Indenture occurs, the principal of and premium, if any, and accrued and
unpaid interest on all the Notes shall be immediately due and payable without any declaration or other act on the part of the Trustee or the Holders. 
 The
Indenture contains provisions permitting the Operating Partnership and the Trustee, with the consent of the Holders of not less than a majority in aggregate principal amount of the Notes at the time outstanding, to execute supplemental indentures
adding any provisions to or changing in any manner or eliminating any of the provisions of the Indenture or of any supplemental indenture with respect to the Notes or any Guarantee or modifying in any manner the rights of the Holders of the Notes,
subject to exceptions set forth in Section 901 and Section 902 of the Base Indenture. Subject to the provisions of the Indenture, the Holders of not less than a majority in aggregate principal amount of the Notes at the time outstanding
may, on behalf of the Holders of all of the Notes, waive any past default or Event of Default with respect to the Notes, subject to exceptions set forth in the Indenture. 

No reference herein to the Indenture and no provision of this Note or of the Indenture shall impair, as among the Operating Partnership and the Holder of the
Notes, the obligation of the Operating Partnership, which is absolute and unconditional, to pay the principal of, premium, if any, on and interest on this Note at the place, at the respective times, at the rate and in the coin or currency herein and
in the Indenture prescribed. 
 Interest on the Notes shall be computed on the basis of a 360-day year consisting of
twelve 30-day months. 
 The Notes are issuable in fully registered form, without coupons, in minimum denominations
of $2,000 and integral multiples of $1,000 in excess thereof. At the office or agency of the Operating Partnership referred to on the face hereof, and in the manner and subject to the limitations provided in the Indenture, without payment of any
service charge but with payment of a sum sufficient to cover any tax, assessment or other governmental charge that may be imposed in connection with any registration of transfer or exchange of Notes, Notes may be transferred or may be exchanged for
a like aggregate principal amount of Notes of any other authorized denominations. The Operating 

  
 A-5 

 
Partnership, any Guarantor, the Trustee and any agent of the Operating Partnership, any Guarantor or the Trustee shall treat the Person in whose name a Note is registered in the Security Register
as the owner of such Note for all purposes whatsoever, and none of the Operating Partnership, any Guarantor, the Trustee or any agent of the Operating Partnership, any Guarantor or the Trustee shall be affected by notice to the contrary. 

The Notes are not subject to redemption through the operation of any sinking fund. 

No recourse for the payment of the principal of or any premium or interest on this Note, or for any claim based hereon or otherwise in respect hereof, and no
recourse under or upon any obligation, covenant or agreement of the Operating Partnership in the Indenture or any supplemental indenture or in any Note, or because of any indebtedness evidenced thereby, shall be had against any past, present or
future general partner, limited partner, member, employee, incorporator, controlling person, shareholder, officer, trustee, director or agent, as such, of the Operating Partnership, the Company, any Possible Future Guarantor or of any of the
Operating Partnership’s, the Company’s or any Possible Future Guarantor’s predecessors or successors, either directly or through the Operating Partnership, the Company or any Possible Future Guarantor or any predecessor or successor
of the Operating Partnership, Company or any Possible Future Guarantor, under any rule of law, statute or constitutional provision or by the enforcement of any assessment or by any legal or equitable proceeding or otherwise, all such liability being
expressly waived and released by the acceptance of the Notes by the Holders thereof and as part of the consideration for the issue of the Notes. 

  
 A-6 

 ASSIGNMENT FORM 

To assign this Note, fill in the form below: 

(I) or (we) assign and transfer this Note to: 
  

	
	  

	
	  

	(Insert assignee’s legal name)
	
	  

	
	  

	
	  

	
	  

	
	  

 (Print or type assignee’s name, address and zip code) 

and irrevocably appoint                      to
transfer this Note on the books of the Operating Partnership. The agent may substitute another to act for him. 
 Date:
                     
  

	
	Your Signature:
	
	  

	
	                     (Sign exactly as your
name appears
                     on the face of this
Note)

 Signature Guarantee*:
                                         
                    
  

	*	 Participant in a recognized Signature Guarantee Medallion Program (or other signature guarantor acceptable to
the Trustee). 

  
 A-7 

 SCHEDULE OF INCREASES OR DECREASES IN THE GLOBAL NOTE * 
 The following increases or decreases in the principal amount of this Global Note
have been made: 
  

															
	Date of
Increase or
Decrease	  	Amount of
decrease in
Principal Amount
at maturity of
this Global Note	 	  	Amount of
increase in
Principal Amount
at maturity of
this Global Note	 	  	Principal Amount
at maturity of
this Global Note
following such
decrease (or
increase)	 	  	Signature of
authorized officer
of Trustee or
Custodian
		  				  				  				  	
		  				  				  				  	
		  				  				  				  	

  

	*	 This schedule should be included only if the Note is issued in global form. 

  
 A-8 

 EXHIBIT B 

[FORM OF SUPPLEMENTAL INDENTURE TO BE DELIVERED BY 

POSSIBLE FUTURE GUARANTORS] 

Supplemental Indenture (this “Supplemental Indenture”), dated as of [●], among AMERICAN HOMES 4 RENT, L.P., a Delaware
limited partnership (the “Operating Partnership”), [POSSIBLE FUTURE GUARANTOR] (the “New Guarantor”), an affiliate of the Operating Partnership, and U.S. BANK NATIONAL ASSOCIATION, a national banking association
organized and existing under the laws of the United States, as trustee (the “Trustee”). 
 RECITALS 

WHEREAS, the Operating Partnership and the Trustee are parties to an Indenture, dated as of February 7, 2018 (the “Base
Indenture”), providing for the issuance from time to time for its lawful purposes of debt securities evidencing the Operating Partnership’s debentures, notes or other evidences of indebtedness, which may be guaranteed by certain
entities. 
 WHEREAS, the Operating Partnership and the Trustee are parties to the Fourth Supplemental Indenture, dated as of July 8,
2021 (the “Fourth Supplemental Indenture,” and together with the Base Indenture, as amended from time to time, the “Indenture”), entered into pursuant to the Base Indenture, which established and provided for the
issuance of, in an initial aggregate principal amount of $300,000,000, a series of the Operating Partnership’s debt securities designated as the “3.375% Senior Notes due 2051” (the “Notes”); 

WHEREAS, the Indenture provides, among other things, that under certain circumstances the New Guarantor shall execute and deliver to the
Trustee a supplemental indenture pursuant to which the New Guarantor shall guarantee the Notes on the terms and conditions set forth in Article Sixteen of the Base Indenture and Section 2.2 of the Fourth Supplemental Indenture; and 

WHEREAS, pursuant to Section 901 of the Base Indenture, the Trustee is authorized to execute and deliver this Supplemental Indenture
without the consent of the Holders. 
 NOW, THEREFORE IT IS AGREED: 

Section 1.    Capitalized terms used herein and not otherwise defined herein are used as defined in the Indenture.

 Section 2.    The New Guarantor hereby agrees in accordance with Article Sixteen of the Base Indenture and
Section 2.2 of the Fourth Supplemental Indenture to, jointly and severally with any other Guarantors of the Notes, fully and unconditionally guarantee the Operating Partnership’s obligations under the Notes on a direct, unsecured and
unsubordinated basis, including the due and punctual payment of principal of, premium, if any, and interest on, the Notes, whether at Stated Maturity, upon redemption, by acceleration or otherwise until released in accordance with the Indenture.

 Section 3.    The New Guarantor acknowledges that it has received and reviewed a copy of the Indenture and all
other documents it deems necessary to review in order to enter into this Supplemental Indenture, and acknowledges and agrees to (i) join and become a party to the Indenture as indicated by its signature below; (ii) be bound by the
Indenture, as of the date hereof, as if made by, and with respect to, each signatory hereto; and (iii) perform all obligations and duties required of a Guarantor pursuant to the Indenture. 

Section 4.    All notices or other communications to the New Guarantor shall be given as provided in Section 105
of the Base Indenture. 
 Section 5.    Except as expressly amended hereby, all the terms, conditions and
provisions of the Indenture shall remain in full force and effect. This Supplemental Indenture shall form a part of the Indenture for all purposes, and every Holder of Notes heretofore or hereafter authenticated and delivered shall be bound hereby.

 Section 6.    THIS SUPPLEMENTAL INDENTURE SHALL BE GOVERNED BY,
AND CONSTRUED IN ACCORDANCE WITH, THE LAWS OF THE STATE OF NEW YORK. THIS SUPPLEMENTAL INDENTURE IS SUBJECT TO THE PROVISIONS OF THE TRUST INDENTURE ACT, THAT ARE REQUIRED TO BE PART OF THIS SUPPLEMENTAL INDENTURE AND SHALL, TO THE EXTENT
APPLICABLE, BE GOVERNED BY SUCH PROVISIONS. 
 Section 7.    This Supplemental Indenture may be executed in
several counterparts, each of which shall be an original and all of which shall constitute one and the same instrument. The exchange of copies of this Supplemental Indenture and of signature pages by facsimile or PDF transmission shall constitute
effective execution and delivery of this Supplemental Indenture as to the parties hereto and may be used in lieu of the original Supplemental Indenture and signature pages for all purposes. Signatures of the parties hereto transmitted by facsimile
or PDF shall be deemed to be their original signatures for all purposes. 
 Section 8.    This Supplemental
Indenture is an indenture supplemental to the Indenture, and the Indenture and this Supplemental Indenture will henceforth be read together. 

Section 9.    The Trustee makes no representation as to and shall not be responsible in any manner whatsoever for or
in respect of the validity or sufficiency of this Supplemental Indenture, the Guarantee of the New Guarantor or for or in respect of the recitals contained herein, all of which recitals are made solely by the Operating Partnership and the New
Guarantor, and the Trustee assumes no responsibility for the same. This Supplemental Indenture is executed and accepted by the Trustee subject to all the terms and conditions set forth in the Indenture with the same force and effect as if those
terms and conditions were repeated at length herein and made applicable to the Trustee with respect hereto. In entering into this Supplemental Indenture, the Trustee shall be entitled to the benefit of every provision of the Indenture relating to
the conduct or affecting the liability or affording protection to the Trustee, whether or not elsewhere herein so provided. 
 [Signature
Page Follows] 

  
 B-2 

 
							
	AMERICAN HOMES 4 RENT, L.P.
		
	By:	 	American Homes 4 Rent, its general partner
			
		 	By:	 	
                     
                    

		 		 	Name:	 	
		 		 	Title:	 	
	
	[POSSIBLE FUTURE GUARANTOR]
		
	By:	 	
                     
                                    

		 	Name:
		 	Title:
	
	[TRUSTEE]
		
	By:	 	
                     
                    

		 	Name:
		 	Title:

  
 B-3ex10-1

 

Exhibit 10.1

 

VISTAGEN THERAPEUTICS, INC.

 

INDEMNIFICATION AGREEMENT

 

THIS
AGREEMENT is entered into, effective as of July 6, 2021 between
VistaGen Therapeutics, Inc., a Nevada corporation (the "Company"),
and Mary L. Rotunno, J.D. (the
“Indemnitee”).

 

WHEREAS, it is
essential to the Company to retain and attract as directors and
officers the most capable persons available;

 

WHEREAS, Indemnitee
is a director of the Company;

 

WHEREAS, both the
Company and Indemnitee recognize the increased risk of litigation
and other claims which may be asserted against directors and
officers of corporations; and

 

WHEREAS, in
recognition of lndemnitee's need for substantial protection against
personal liability in order to enhance Indemnitee's continued and
effective service to the Company, and in order to induce Indemnitee
to provide services to the Company as a director, the Company
wishes to provide in this Agreement for the indemnification of and
the advancing of expenses to Indemnitee to the fullest extent
(whether partial or complete) permitted by law and as set forth in
this Agreement, and, to the extent insurance is maintained, for the
coverage of Indemnitee under the Company's directors' and officers'
liability insurance policies.

 

NOW,
THEREFORE, in consideration of the above premises and of
lndemnitee's continuing to serve the Company directly or, at its
request, with another enterprise, and intending to be legally bound
hereby, the parties agree as follows:

 

1.
Certain Definitions:

 

(a)
Board: the Board of
Directors of the Company.

 

(b)
Change in Control:
shall be deemed to have occurred if (i) any "person" (as such term
is used in Sections 13(d) and 14(d) of the Securities Exchange Act
of 1934, as amended), other than a trustee or other fiduciary
holding securities under an employee benefit plan of the Company or
a corporation owned directly or indirectly by the shareholders of
the Company in substantially the same proportions as their
ownership of stock of the Company, is or becomes the "Beneficial
Owner" (as defined in Rule 13d-3 under said Act), directly or
indirectly, of securities of the Company representing 20% or more
of the total voting power represented by the Company's then
outstanding Voting Securities, or (ii) during any period of two
consecutive years, individuals who at the beginning of such period
constitute the Board and any new director whose election by the
Board or nomination for election by the Company's shareholders was
approved by a vote of at least two-thirds (2/3) of the directors
then still in office who either were directors at the beginning of
the period or whose election or nomination for election was
previously so approved, cease for any reason to constitute a
majority thereof, or (iii) the shareholders of the Company approve
a merger or consolidation of the Company with any other
corporation, other than a merger or consolidation that would result
in the Voting Securities of the Company outstanding immediately
prior thereto continuing to represent (either by remaining
outstanding or by being conve1ied into Voting Securities of the
surviving entity) at least 80% of the total voting power
represented by the Voting Securities of the Company or such
surviving entity outstanding immediately after such merger or
consolidation, or the shareholders of the Company approve a plan of
complete liquidation of the Company or an agreement for the sale or
disposition by the Company (in one transaction or a series of
transactions) of all or substantially all of the Company's
assets.

 

(c)
Expenses: any
expense, liability, or loss, including attorneys' fees, judgments,
fines, ERISA excise taxes and penalties, amounts paid or to be paid
in settlement, any interest, assessments, or other charges imposed
thereon, and any federal, state, local, or foreign taxes imposed as
a result of the actual or deemed receipt of any payments under this
Agreement, paid or incurred in connection with investigating,
defending, being a witness in, or participating in (including on
appeal), or preparing for any of the foregoing in, any Proceeding
relating to any Indemnifiable Event.

 

 

 

-1-

 

 

 

(d)
Indemnifiable
Event: any event or occurrence that takes place either prior
to or after the execution of this Agreement, related to the fact
that Indemnitee is or was a director of the Company, or while a
director is or was serving at the request of the Company as a
director, officer, employee, trustee, agent, or fiduciary of
another foreign or domestic corporation, partnership, joint
venture, employee benefit plan, trust, or other enterprise, or was
a director, officer, employee, or agent of a foreign or domestic
corporation that was a predecessor corporation of the Company or of
another enterprise at the request of such predecessor corporation,
or related to anything done or not done by Indemnitee in any such
capacity, whether or not the basis of the Proceeding is alleged
action in an official capacity as a director, officer, employee, or
agent or in any other capacity while serving as a director,
officer, employee, or agent of the Company, as described
above.

 

(e)
Independent
Counsel: the person or body appointed in connection with
Section 3.

 

(f)
Proceeding: any
threatened, pending, or completed action, suit, or proceeding
(including an action by or in the right of the Company), or any
inquiry, hearing, or investigation, whether conducted by the
Company or any other party, that Indemnitee in good faith believes
might lead to the institution of any such action, suit, or
proceeding, whether civil, criminal, administrative, investigative,
or other.

 

(g)
Reviewing Party:
the person or body appointed in accordance with Section
3.

 

(h)
Voting Securities:
any securities of the Company that vote generally in the election
of directors.

 

2.
Agreement to
Indemnify.

 

(a)
General Agreement.
General Agreement. In the event Indemnitee was, is, or becomes a
party to or witness or other participant in, or is threatened to be
made a party to or witness or other participant in, a Proceeding by
reason of (or arising in part out of) an Indemnifiable Event, the
Company shall indemnify Indemnitee from and against any and all
Expenses to the fullest extent permitted by law, as the same exists
or may hereafter be amended or interpreted (but in the case of any
such amendment or interpretation, only to the extent that such
amendment or interpretation permits the Company to provide broader
indemnification rights than were permitted prior thereto). The
parties hereto intend that this Agreement shall provide for
indemnification in excess of that expressly permitted by statute,
including, without limitation, any indemnification provided by the
Company's Articles of Incorporation, its Bylaws, vote of its
shareholders or disinterested directors, or applicable
law.

 

(b)
Initiation of
Proceeding. Notwithstanding anything in this Agreement to
the contrary, Indemnitee shall not be entitled to indemnification
pursuant to this Agreement in connection with any Proceeding
initiated by Indemnitee against the Company or any director of the
Company unless (i) the Company has joined in or the Board has
consented to the initiation of such Proceeding; (ii) the Proceeding
is one to enforce indemnification rights under Section 5; or (iii)
the Proceeding is instituted after a Change in Control (other than
a Change in Control approved by a majority of the directors on the
Board who were directors immediately prior to such Change in
Control) and Independent Counsel has approved its
initiation.

 

(c)
Expense Advances.
If so requested by Indemnitee, the Company shall advance (within
ten business days of such request) any and all Expenses to
Indemnitee (an "Expense Advance"); provided that, if and to the
extent that the Reviewing Party determines that Indemnitee would
not be permitted to be so indemnified under applicable law, the
Company shall be entitled to be reimbursed by Indemnitee (who
hereby agrees to reimburse the Company) for all such amounts
theretofore paid. If Indemnitee has commenced or commences legal
proceedings in a court of competent jurisdiction to secure a
determination that Indemnitee should be indemnified under
applicable law, as provided in Section 4, any determination made by
the Reviewing Party that Indemnitee would not be permitted to be
indemnified under applicable law shall not be binding ai1d
Indemnitee shall not be required to reimburse the Company for any
Expense Advance until a final judicial determination is made with
respect thereto (as to which all rights of appeal therefrom have
been exhausted or have lapsed). Indemnitee's obligation to
reimburse the Company for Expense Advances shall be unsecured and
no interest shall be charged thereon.

 

(d)
Mandatory
Indemnification. Notwithstanding any other provision of this
Agreement, to the extent that Indemnitee has been successful on the
merits in defense of any Proceeding relating in whole or in part to
an Indemnifiable Event or in defense of any issue or matter
therein, Indemnitee shall be indemnified against all Expenses
incurred in connection therewith.

 

 

-2-

 

 

 

 

(e)
Partial
Indemnification. If indemnitee is entitled under any
provision of this Agreement to indemnification by the Company for
some or a portion of Expenses, but not, however, for the total
amount thereof, the Company shall nevertheless indemnify Indemnitee
for the po1iion thereof to which Indemnitee is
entitled.

 

(f)
Prohibited
Indemnification. No indemnification pursuant to this
Agreement shall be paid by the Company on account of any Proceeding
in which final unappealed judgment beyond the right of appeal is
rendered against Indemnitee for an accounting of profits made from
the purchase or sale by Indemnitee of securities of the Company
pursuant to the provisions of Section 16(b) of the Securities
Exchange Act of 1934, as amended, or similar provisions of any
federal, state, or local laws.

 

3.
Reviewing Party.
Prior to any Change in Control, the Reviewing Party shall be any
appropriate person or body consisting of a member or members of the
Board or any other person or body appointed by the Board who is not
a party to the particular Proceeding with respect to which
Indemnitee is seeking indemnification; after a Change in Control,
the Reviewing Party shall be the Independent Counsel referred to
below. With respect to all matters arising after a Change in
Control (other than a Change in Control approved by a majority of
the directors on the Board who were directors immediately prior to
such Change in Control) concerning the rights of lndemnitee to
indemnity payments and Expense Advances under this Agreement or any
other agreement or under applicable law or the Company's Articles
of Incorporation or Bylaws now or hereafter in effect relating to
indemnification for Indemnifiable Events, the Company shall seek
legal advice only from Independent Counsel selected by Indemnitee
and approved by the Company (which approval shall not be
unreasonably withheld), and who has not otherwise performed
services for the Company or the Indemnitee (other than in
connection with indemnification matters) within the last five
years. The Independent Counsel shall not include any person who,
under the applicable standards of professional conduct then
prevailing, would have a conflict of interest in representing
either the Company or Indemnitee in an action to determine
Indemnitee's rights under this Agreement. Such counsel, among other
things, shall render its written opinion to the Company and
Indemnitee as to whether and to what extent the Indemnitee should
be permitted to be indemnified under applicable law. The Company
agrees to pay the reasonable fees of the Independent Counsel and to
indemnify fully such counsel against any and all expenses
(including attorneys' fees), claims, liabilities, loss, and damages
arising out of or relating to this Agreement or the engagement of
Independent Counsel pursuant hereto.

 

4.
Indemnification Process
and Appeal.

 

(a)
Indemnification
Payment. Indemnitee shall be entitled to indemnification of
Expenses, and shall receive payment thereof, from the Company in
accordance with this Agreement as soon as practicable after
Indemnitee has made written demand on the Company for
indemnification, unless the Reviewing Party has given a written
opinion to the Company that Indemnitee is not entitled to
indemnification under applicable law.

 

(b)
Suit to Enforce
Rights. Regardless of any action by the Reviewing Party, if
Indemnitee has not received full indemnification within thirty days
after making a demand in accordance with Section 4(a), Indemnitee
shall have the right to enforce its indemnification rights under
this Agreement by commencing litigation in any court in the State
of California having subject matter jurisdiction thereof and in
which venue is proper seeking an initial determination by the court
or challenging any determination by the Reviewing Party or any
aspect thereof. The Company hereby consents to service of process
and to appear in any such proceeding. Any determination by the
Reviewing Party not challenged by the Indemnitee shall be binding
on the Company and Indemnitee. The remedy provided for in this
Section 4 shall be in addition to any other remedies available to
Indemnitee in law or equity.

 

(c)
Defense to
Indemnification, Burden of Proof, and Presumptions. It shall
be a defense to any action brought by Indemnitee against the
Company to enforce this Agreement (other than an action brought to
enforce a claim for Expenses incurred in defending a Proceeding in
advance of its final disposition where the required undertaking has
been tendered to the Company) that it is not permissible under
applicable law for the Company to indemnify Indemnitee for the
amount claimed. In connection with any such action or any
determination by the Reviewing Party or otherwise as to whether
Indemnitee is entitled to be indemnified hereunder, the burden of
proving such a defense or determination shall be on the Company.
Neither the failure of the Reviewing Party or the Company
(including its Board, independent legal counsel, or its
shareholders) to have made a determination prior to the
commencement of such action by Indemnitee that indemnification of
the claimant is proper under the circumstances because he has met
the standard of conduct set forth in applicable law, nor an actual
determination by the Reviewing Party or Company (including its
Board, independent legal counsel, or its shareholders) that the
Indemnitee had not met such applicable standard of conduct, shall
be a defense to the action or create a presumption that the
Indemnitee has not met the applicable standard of conduct. For
purposes of this Agreement, the termination of any claim, action,
suit, or proceeding, by judgment, order, settlement (whether with
or without court approval), conviction, or upon a plea of nolo
contendere, or its equivalent, shall not create a presumption that
Indemnitee did not meet any particular standard of conduct or have
any particular belief or that a court has determined that
indemnification is not permitted by applicable law.

 

 

-3-

 

 

 

5.
Indemnification for
Expenses Incurred in Enforcing Rights. The Company shall
indemnify Indemnitee against any and all Expenses that are incurred
by Indemnitee in connection with any action brought by Indemnitee
for

 

(i)
indemnification of Expenses by the Company under this Agreement or
any other agreement or under applicable law or the Company's
Articles of Incorporation or Bylaws now or hereafter in effect
relating to indemnification for Indemnifiable Events,
and/or

 

(ii)
recovery under directors' and officers' liability insurance
policies maintained by the Company, but only in the event that
Indemnitee ultimately is determined to be entitled to such
indemnification or insurance recovery, as the case may be. In
addition, the Company shall, if so requested by Indemnitee, advance
the foregoing Expenses to Indemnitee, subject to and in accordance
with Section 2(c).

 

6.
Notification and Defense
of Proceeding.

 

(a)
Notice. Promptly
after receipt by Indemnitee of notice of the commencement of any
Proceeding, Indemnitee will, if a claim in respect thereof is to be
made against the Company under this Agreement, notify the Company
of the commencement thereof; but the omission so to notify the
Company will not relieve it from any liability that it may have to
Indemnitee, except as provided in Section 6(c).

 

(b)
Defense. With
respect to any Proceeding as to which Indemnitee notifies the
Company of the commencement thereof, the Company will be entitled
to participate in the Proceeding at its own expense and except as
otherwise provided below, to the extent the Company so wishes, it
may assume the defense thereof with counsel reasonably satisfactory
to Indemnitee. After notice from the Company to Indemnitee of its
election to assume the defense of any Proceeding, the Company will
not be liable to Indemnitee under this Agreement or otherwise for
any Expenses subsequently incurred by Indemnitee in connection with
the defense of such Proceeding other than reasonable costs of
investigation or as otherwise provided below. Indemnitee shall have
the right to employ his own counsel in such Proceeding, but all
Expenses related thereto incurred after notice from the Company of
its assumption of the defense shall be at Indemnitee's expense
unless: (i) the employment of counsel by Indemnitee has been
authorized by the Company, (ii) Indemnitee has reasonably
determined that there may be a conflict of interest between
Indemnitee and the Company in the defense of the Proceeding, after
a Change in Control (other than a Change in Control approved by a
majority of the directors on the Board who were directors
immediately prior to such Change in Control), the employment of
counsel by Indemnitee has been approved by the Independent Counsel,
or (iv) the Company shall not in fact have employed counsel to
assume the defense of such Proceeding, in each of which case all
Expenses of the Proceeding shall be borne by the Company. The
Company shall not be entitled to assume the defense of any
Proceeding brought by or on behalf of the Company or as to which
Indemnitee shall have made the determination provided for in (ii)
above.

 

(c)
Settlement of
Claims. The Company shall not be liable to indemnify
Indemnitee under this Agreement or otherwise for any amounts paid
in settlement of any Proceeding effected without the Company's
written consent, provided, however, that if a Change in Control has
occurred (other than a Change in Control approved by a majority of
the directors on the Board who were directors immediately prior to
such Change in Control), the Company shall be liable for
indemnification of Indemnitee for amounts paid in settlement if the
Independent Counsel has approved the settlement. The Company shall
not settle any Proceeding in any manner that would impose any
penalty or limitation on Indemnitee without Indemnitee's written
consent. Neither the Company nor the Indemnitee will unreasonably
withhold their consent to any proposed settlement. The Company
shall not be liable to indemnify the Indemnitee under this
Agreement with regard to any judicial award if the Company was not
given a reasonable and timely opportunity, at its expense, to
participate in the defense of such action; the Company's liability
hereunder shall not be excused if participation in the Proceeding
by the Company was barred by this Agreement.

 

 

-4-

 

 

 

7.
Establishment of
Trust. In the event of a Change in Control (other than a
Change in Control approved by a majority of the directors on the
Board who were directors immediately prior to such Change in
Control) the Company shall, upon written request by Indemnitee,
create a Trust for the benefit of the Indemnitee and from time to
time upon written request of Indemnitee shall fund the Trust in an
amount sufficient to satisfy any and all Expenses reasonably
anticipated at the time of each such request to be incurred in
connection with investigating, preparing for, participating in,
and/or defending any Proceeding relating to an Indemnifiable Event.
The amount or amounts to be deposited in the Trust pursuant to the
foregoing funding obligation shall be determined by the Reviewing
Party. The terms of the Trust shall provide that (i) the Trust
shall not be revoked or the principal thereof invaded, without the
written consent of the Indemnitee, (ii) the Trustee shall advance,
within ten business days of a request by the Indemnitee, any and
all Expenses to the Indemnitee (and the Indemnitee hereby agrees to
reimburse the Trust under the same circumstances for which the
Indemnitee would be required to reimburse the Company under Section
2(c) of this Agreement), (iii) the Trust shall continue to be
funded by the Company in accordance with the funding obligation set
forth above, (iv) the Trustee shall promptly pay to the Indemnitee
all amounts for which the Indemnitee shall be entitled to
indemnification pursuant to this Agreement or otherwise, and (v)
all unexpended funds in the Trust shall revert to the Company upon
a final determination by the Reviewing Party or a court of
competent jurisdiction, as the case may be, that the Indemnitee has
been fully indemnified under the terms of this Agreement. The
Trustee shall be chosen by the Indemnitee. Nothing in this Section
7 shall relieve the Company of any of its obligations under this
Agreement. All income earned on the assets held in the Trust shall
be reported as income by the Company for federal, state, local, and
foreign tax purposes. The Company shall pay all costs of
establishing and maintaining the Trust and shall indemnify the
Trustee against any and all expenses (including attorneys' fees),
claims, liabilities, loss, and damages arising out of or relating
to this Agreement or the establishment and maintenance of the
Trust.

 

8.
Non-Exclusivity.
The rights of Indemnitee hereunder shall be in addition to any
other rights Indemnitee may have under the Company's Articles of
Incorporation, Bylaws, applicable law, or otherwise. To the extent
that a change in applicable law (whether by statute or judicial
decision) permits greater indemnification by agreement than would
be afforded currently under the Company's Articles of
Incorporation, Bylaws, applicable law, or this Agreement, it is the
intent of the parties that Indemnitee enjoy by this Agreement the
greater benefits so afforded by such change.

 

9.
Liability
Insurance. To the extent the Company maintains an insurai1ce
policy or policies providing directors' and officers' liability
insurance, Indemnitee shall be covered by such policy or policies,
in accordance with its or their terms, to the maximum extent of the
coverage available for any Company director or
officer.

 

10.
Period of
Limitations. No legal action shall be brought and no cause
of action shall be asserted by or on behalf of the Company or any
affiliate of the Company against Indemnitee, Indemnitee's spouse,
heirs, executors, or personal or legal representatives after the
expiration of two (2) years from the date of accrual of such cause
of action, or such longer period as may be required by state law
under the circumstances. Any claim or cause of action of the
Company or its affiliate shall be extinguished and deemed released
unless asserted by the timely filing of a legal action within such
period; provided, however, that if any shorter period of
limitations is otherwise applicable to any such cause of action the
shorter period shall govern.

 

11.
Amendment of this
Agreement. No supplement, modification, or amendment of this
Agreement shall be binding unless executed in writing by both of
the parties hereto. No waiver of any of the provisions of this
Agreement shall be binding unless in the form of a writing signed
by the pa1iy against whom enforcement of the waiver is sought, and
no such waiver shall operate as a waiver of any other provisions
hereof (whether or not similar), nor shall such waiver constitute a
continuing waiver. Except as specifically provided herein, no
failure to exercise or any delay in exercising any right or remedy
hereunder shall constitute a waiver thereof.

 

12.
Subrogation. In the
event of payment under this Agreement, the Company shall be
subrogated to the extent of such payment to all of the rights of
recovery of Indemnitee, who shall execute all papers required and
shall do everything that may be necessary to secure such rights,
including the execution of such documents necessary to enable the
Company effectively to bring suit to enforce such
rights.

 

 

 

-5-

 

 

 

13.
No Duplication of
Payments. The Company shall not be liable under this
Agreement to make any payment in connection with any claim made
against Indemnitee to the extent Indemnitee has otherwise received
payment (under any insurance policy, Bylaw, or otherwise) of the
amounts otherwise Indemnifiable hereunder.

 

14.
Binding Effect.
This Agreement shall be binding upon and inure to the benefit of
and be enforceable by the parties hereto and their respective
successors (including any direct or indirect successor by purchase,
merger, consolidation, or otherwise to all or substantially all of
the business and/or assets of the Company), assigns, spouses,
heirs, and personal and legal representatives. The Company shall
require and cause any successor (whether direct or indirect by
purchase, merger, consolidation, or otherwise) to all,
substantially all, or a substantial part, of the business and/or
assets of the Company, by written agreement in form and substance
satisfactory to Indemnitee, expressly to assume and agree to
perform this Agreement in the same manner and to the same extent
that the Company would be required to perform if no such succession
had taken place. The indemnification provided under this Agreement
shall continue as to Indemnitee for any action taken or not taken
while serving in an indemnified capacity pertaining to an
Indemnifiable Event even though he may have ceased to serve in such
capacity at the time of any Proceeding.

 

15.
Severability. If
any provision (or portion thereof) of this Agreement shall be held
by a court of competent jurisdiction to be invalid, void, or
otherwise unenforceable, the remaining provisions shall remain
enforceable to the fullest extent permitted by law. Furthermore, to
the fullest extent possible, the provisions of this Agreement
(including, without limitation, each portion of this Agreement
containing any provision held to be invalid, void, or otherwise
unenforceable, that is not itself invalid, void, or unenforceable)
shall be construed so as to give effect to the intent manifested by
the provision held invalid, void, or unenforceable.

 

16.
Governing Law. This
Agreement shall be governed by and construed and enforced in
accordance with the laws of the State of California applicable to
contracts made and to be performed in such State without giving
effect to the principles of conflicts of laws.

 

17.
Notices. All
notices, demands, and other communications required or permitted
hereunder shall be made in writing and shall be deemed to have been
duly given if delivered by hand, against receipt, or mailed,
postage prepaid, certified or registered mail, return receipt
requested, and addressed to the Company at:

 

VistaGen
Therapeutics, Inc.

343
Allerton Avenue

South
San Francisco, CA 94080

Attention: Chief
Executive Officer

 

and to
Indemnitee at:

 

Mary L.
Rotunno, J.D.

169 San
Aleso Avenue

San
Francisco, CA 94127

 

Notice
of change of address shall be effective only when done in
accordance with this Section. All notices complying with this
Section shall be deemed to have been received on the date of
delivery or on the third business day after mailing.

 

 

 

 

 

-6-

 

 

 

IN
WITNESS WHEREOF, the parties hereto have duly executed and
delivered this Agreement as of the day specified
above.

 

VISTAGEN
THERAPEUTICS, INC.

 

 

 

By:
/s/ Shawn K.
Singh

Name:
Shawn K. Singh

Title:
Chief Executive Officer

 

/s/ 
Mary L. Rotunno, J.D.

Mary L.
Rotunno, J.D.

 

 

 

-7-

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