Document:

<PAGE>

                                                                   Exhibit 10.56

THESE SECURITIES HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS
AMENDED (THE "1933 ACT"). THEY MAY NOT BE SOLD, OFFERED FOR SALE, PLEDGED, OR
HYPOTHECATED IN THE ABSENCE OF AN EFFECTIVE REGISTRATION STATEMENT RELATED
THERETO OR AN OPE41ON OF COUNSEL (WHICH MAY BE COMPANY COUNSEL) REASONABLY
SATISFACTORY TO THE COMPANY THAT SUCH REGISTRATION IS NOT REQUIRED UNDER THE
1933 ACT.

                               WARRANT AGREEMENT

                 To Purchase 10,000 Shares of Common Stock of

                                ONTOGENY, INC.

              Dated as of October 1, 1997 (the "Effective Date")

     WHEREAS, Ontogeny, Inc., a Delaware corporation (the "Company") has entered
into a Master Equipment Lease Agreement dated as of November 7, 1995, Lease Line
Schedule No. 03, and certain other related schedules and other documents
(collectively, as amended or supplemented from time to time the "Leases") with
Lighthouse Capital Partners. L.P., a Delaware limited partnership (the
"Warrantholder"); and

     WHEREAS, the Company desires to grant to Warrantholder, in consideration
for such Leases, the right to purchase shares of its Common Stock:

     NOW, THEREFORE, in consideration of the Warrantholder executing and
delivering such Leases and in consideration of the mutual covenants and
agreements contained herein, the Company and Warrantholder agree as follows:

1.   GRANT OF THE RIGHT TO PURCHASE COMMON STOCK

     The Company hereby grants to the Warrantholder, and the Warrantholder is
entitled, upon the terms and subject to the conditions hereinafter set forth, to
subscribe to and purchase, from the Company, at a price per share equal to $2.50
(the "Exercise Price"), 10,000 fully paid and nonassessable shares of the
Company's Common Stock, $.01 par value per share (the "Common Stock"). The
number and purchase price of such shares are subject to adjustment as provided
in Section 8 hereof;

2.   TERM OF THE WARRANT AGREEMENT.

     (a)  Except as otherwise provided for herein, the term of this Warrant
Agreement and the right to purchase Common Stock as granted herein shall
commence on the Effective Date and shall be exercisable for a period of ten (10)
years.

     (b)  Acceleration of Term Upon Initial Public Offering. Notwithstanding the
term of this Warrant Agreement fixed pursuant to Section 2(a) hereof,
Warrantholders right to purchase Common Stock as granted herein shall expire, if
not previously exercised, immediately upon the closing of the issuance and sale
of shares of Common Stock of the Company in the Company's first public offering
of securities for its own account pursuant to an effective registration
statement under the 1933 Act (the "Initial Public Offering"), provided that the
underwriters request that the Warrantholder exercise
<PAGE>

this Warrant within a reasonable period of time, anything to the contrary in
this Warrant Agreement notwithstanding, the rights to purchase will not expire
until ten (10) business days after the Company delivers such notice to the
Warrantholder. Such notice shall also contain such details of the proposed
Initial Public Offering as are reasonable in the circumstances and notice that
this Warrant Agreement is expected to expire upon the later of (i) the closing
of the Initial Public Offering or (ii) the date which is ten (10) days after the
date the Warrantholder receives the notice. If such closing does not take place
within six (6) months, the Company shall promptly notify the Warrantholder that
such proposed transaction has been terminated. Anything to the contrary in this
Warrant Agreement notwithstanding the Warrantholder may rescind any exercise of
its purchase rights promptly after such notice of termination of the proposed
transaction if the exercise of Warrants occurred after the Company notified the
Warrantholder that the Initial Public Offering was proposed or if the exercise
were otherwise precipitated by such proposed Initial Public Offering. In the
event of such rescission, the Warrants will continue to be exercisable on the
same terms and conditions.

3.   EXERCISE OF THE PURCHASE RIGHTS.

     The purchase rights set forth in this Warrant Agreement are exercisable by
the Warrantholder, in whole or in part, at any time, or from time to time, prior
to the expiration of the term set forth in Section 2 above, by tendering to the
Company at its principal office a notice of exercise in the form attached hereto
as Exhibit I (the "Notice of Exercise"), duly completed and executed. Promptly
upon receipt of the Notice of Exercise and the payment of the purchase price in
accordance with the terms set forth below, and in no event later than twenty-one
(21) days thereafter, the Company shall issue to the Warrantholder a certificate
for the number of shares of Common Stock purchased and shall execute the Notice
of Exercise indicating the number of shares which remain subject to future
purchases, if any.

     The Exercise Price may be paid at the Warrantholder's election either (i)
by cash or check, (ii) by the surrender by the Warrantholder to the Company of
any promissory notes or other obligations issued by the Company, with all such
notes and obligations so surrendered being credited against the Exercise Price
in an amount equal to the principal amount thereof plus accrued interest to the
date of surrender, (iii) by surrender of Warrants ("Net Issuance") as determined
below, or (iv) by any combination of the foregoing. If the Warrantholder elects
the Net Issuance method, the Company will issue Common Stock in accordance with
the following formula:

          X    =         Y(A-B)
                         ------
                            A

Where:    X    =         the number of shares of Common Stock to be issued to
                         the Warrantholder.

          Y    =         the number of shares of Common Stock requested to be
                         exercised under this Warrant Agreement.

          A    =         the fair market value of one (1) share of Common Stock.

          B    =         the Exercise Price in effect under the Warrant
                         Agreement at the

                                      -2-
<PAGE>

                         time the net issue election is made pursuant to this
                         Section 3.

     As used herein, current fair market value of a share of Common Stock shall
mean with respect to each share of Common Stock:

          (i)    if the exercise is in connection with an initial public
offering, and if the Company's Registration Statement relating to such public
offering has been declared effective by the SEC, then the initial "Price to
Public" specified in the final prospectus with respect to the offering;

          (ii)   if this Warrant is exercised after, and not in connection with
the Company's initial public offering, and:

                 (1)  if traded on a securities exchange, the fair market value
of the Common Stock dull be deemed to be the average of the closing prices over
a twenty-one (2 1) day period ending three days before the day the current fair
market value of the securities is being determined and the fair market value of
the Common Stock shall be deemed to be such fair market value of the Common
Stock:

                 (2)  if actively traded over-the-counter, the fair market value
of the Common Stock shall be deemed to be the average of the closing bid and
asked prices quoted on the NASDAQ system (or similar system) over the twenty-one
(21) day period ending three days before the day the current fair market value
of the securities is being determined and the fair market value of the Common
Stock shall be deemed to be such fair market value of the Common Stock; and

          (iii)  if at any time the Common Stock is not listed on any securities
exchange or quoted in the NASDAQ System or the over-the-counter market the
current fair market value of the Common Stock shall be the highest price per
share which the Company could obtain from a willing buyer (not a current
employee or director) for shares of Common Stock sold by the Company, from
authorized but unissued shares, as determined in good faith by its Board of
Directors, and the fair market value of the Common Stock shall be deemed to be
such fair market value of the Common Stock; provided, that if the Company shall
become subject to a merger, acquisition or other consolidation pursuant to which
the Company is not me surviving party, the fair market value of the Common Stock
shall be deemed to be the value per share of the consideration received by the
holders of the Company's Common Stock pursuant to such merger or acquisition and
the fair market value of the Common Stock shall be deemed to be such fair market
value of the Common Stock.

     Upon partial exercise by either cash or Net Issuance, the Company shall
promptly issue an amended Warrant Agreement representing the remaining number of
shares purchasable hereunder. All other term and conditions of such amended
Warrant Agreement shall be identical to those contained herein, including, but
not limited to the Effective Date hereof.

                                      -3-
<PAGE>

4.   RESERVATION OF SHARES.

     (a)  Authorization and Reservation of Shares. During the term of this
Warrant Agreement, the Company will at all times have authorized and reserved a
sufficient number of shares of its Common Stock to provide for the exercise of
the rights to purchase Common Stock as provided for herein.

     (b)  Registration or Listing. If any shares of Common Stock required to be
reserved hereunder require registration with or approval of any governmental
authority under any Federal or State law (other than any registration under the
1933 Act, as then in effect, or any similar Federal statute then enforced, or
any state securities law, required by reason of any transfer involved in such
conversion), or listing on any domestic securities exchange, before such shares
may be issued upon conversion, the Company will, at its expense and as
expeditiously as possible, use its best efforts to cause such shares to be duly
registered, listed or approved for listing on such domestic securities exchange,
as the case may be.

5.   NO FRACTIONAL SHARES OR SCRIP.

     No fractional shares or scrip representing Fractional shares shall be
issued upon the exercise of the Warrant, but in lieu of such fractional shares
the Company shall make a cash payment therefor upon the basis of the Exercise
Price then in effect.

6.   NO RIGHTS AS SHAREHOLDER.

     This Warrant Agreement does not entitle the Warrantholder to any voting
rights or other rights as a shareholder of the Company prior to the exercise of
the Warrant

7.   WARRANTHOLDER REGISTRY.

     The Company shall maintain a registry showing the name and address of the
registered holder of this Warrant Agreement.

8.   ADJUSTMENT RIGHTS.

     The purchase price per share and the number of shares of Common Stock
purchasable hereunder are subject to adjustment as follows:

     (a)  Merger and Sale of Assets. If at any time there shall be a capital
reorganization of the shares of the Company's stock (other than a combination,
reclassification, exchange or subdivision of shares otherwise provided for
herein), or a merger or consolidation of the Company with or into another
corporation when the Company is not the surviving corporation, or the sale of
all or substantially all of the Company's properties and assets to any other
person (hereinafter referred to as a "Merger Event"), then, as a part of such
Merger Event, lawful provision shall be made so that the Warrantholder shall
thereafter be entitled to receive, upon exercise of the Warrant, the number and
kind of shares of stock or other securities of the successor corporation or cash
or other property that the Warrantholder would have been entitled to receive if
such Warrantholder had exercised this Warrant immediately prior to the Merger
Event. In any such case, appropriate adjustment (as determined in good faith by
the Company's Board of Directors) shall be made in the application of the
provisions of

                                      -4-
<PAGE>

this Warrant Agreement with respect to the rights and interest of the
Warrantholder after the Merger Event to the end that the provisions of this
Warrant Agreement (including adjustments of the Excuse Price and number of
shares of Common Stock purchasable) shall be applicable to the greatest extent
possible.

     (b)  Reclassification of Shares. If the Company at any time shall, by
combination, reclassification, exchange or subdivision of securities or
otherwise, change any of the Common Stock into the same or a different number of
securities of any other class or classes, this Warrant Agreement shall
thereafter represent the right to acquire such number and kind of securities as
would have been issuable as the result of such change with respect to the
securities which were subject to the purchase rights under this Warrant
Agreement immediately prior to such combination, reclassification, exchange,
subdivision or other change.

     (c)  Subdivision or Combination of Shares. If the Company at any time shall
combine or subdivide (by split-up or otherwise) its Common Stock or issue
additional shares of Common Stock in payment of a stock dividend on the Common
Stock, the number of shares of Common Stock issuable on the exercise of this
Warrant Agreement shall forthwith be proportionately increased in the case of a
subdivision or stock dividend, or proportionately decreased in the case of a
combination, and the Exercise Price shall be proportionately decreased in the
case of a subdivision or stock dividend, or proportionately increased in the
case of a combination.

     (d)  Antidilution Rights. Additional antidilution rights applicable to the
Common Stock purchasable hereunder are as set forth in the Company's Certificate
of Incorporation, as amended through the Effective Date, a true and complete
copy of which is attached hereto as Exhibit III (the "Charter"). The Company
shall promptly provide the Warrantholder with any restatement, amendment,
modification or waiver of the Charter affecting such anti-dilution rights. The
Company will give Warrantholder notices of all dilutive issuances of its stock.

     (e)  Notice of Adjustments. If: (i) the Company shall declare any dividend
or distribution upon its stock, whether in cash, property, stock or other
securities; (ii) the Company shall offer for subscription pro rata to the
holders of any class of its Preferred Stock or other convertible stock any
additional shares of stock of any class or other rights; (iii) there shall be
any Merger Event; or (iv) there shall be any voluntary or involuntary
dissolution, liquidation or winding up of the Company; then, in connection with
each such event the Company shall send to the Warrantholder (A) at least twenty
(20) days prior written notice of the date on which the books of the Company
shall close or a record shall be taken for such dividend, distribution,
subscription rights (specifying the date on which the holders of Common Stock
shall be entitled thereto) or for determining rights to vote in respect of such
Merger Event dissolution, liquidation or winding up; and (B) in the case of any
such Merger Event, dissolution, liquidation or winding up, at least twenty (20)
days prior written notice of the date when the same shall take place (and
specifying the date on which the holders of Common Stock shall be entitled to
exchange their Common Stock for securities or other property deliverable upon
such Merger Event dissolution, liquidation or winding up).

     Each such written notice shall set forth, in reasonable detail (i) the
event requiring the adjustment, (iii) the amount of the adjustment (iii) the
method by which such adjustment was calculated, (iv) the Exercise Price, and (v)
the number of shares

                                      -5-
<PAGE>

subject to purchase hereunder after giving effect to such adjustment, and shall
be given by first class mail, postage prepaid, addressed to the Warrantholder,
at the address as shown on the books of the Company.

     (f)  Timely Notice. Failure to timely provide such notice required by
subsection (e) above shall entitle Warrantholder to retain the benefit of the
applicable notice period notwithstanding anything to the contrary contained in
any insufficient notice received by Warrantholder. The notice period shall begin
on the date Warrantholder actually receives a written notice containing all the
information specified above.

9.   REPRESENTATIONS, WARRANTIES AND COVENANTS OF THE COMPANY.

     (a)  Reservation of Common Stock. The Common Stock issuable upon exercise
of the Warrantholders rights and the Common Stock issuable upon conversion
thereof has been duty and validly reserved and, when issued in accordance with
the provisions of this Warrant Agreement, will be validly issued, fully paid and
non-assessable, and will be free of any taxes, liens, charges or encumbrances of
any nature whatsoever; provided, however, that the Common Stock issuable
pursuant to this Warrant Agreement may be subject to restrictions on transfer
under state and/or Federal securities laws. The Company has made available to
the Warrantholder true, correct and complete copies of its Charter and Bylaws,
as amended, and minutes of all Board of Directors (including all committees of
the Board of Directors, if any) and Shareholder meetings from inception through
September 8, 1997. The issuance of certificates for shares of Common Stock upon
exercise of the Warrant shall be made without charge to the Warrantholder for
any issuance tax in respect thereof, or other cost incurred by the Company in
connection with such exercise and the related issuance of shares of Common
Stock. the Company shall not be required to pay any tax which may be payable in
respect of any transfer involved and the issuance and delivery of any
certificate in a name other than that of the Warrantholder

     (b)  Due Authority. The execution and delivery by the Company of this
Warrant Agreement and the performance of all obligations of the Company
hereunder, including the issuance to Warrantholder of the right to acquire the
shares of Common Stock, have been duly authorized by all necessary corporate
action on the part of the Company, and the Leases and this Warrant Agreement are
not inconsistent with the Company's Charter or Bylaws, do not contravene any law
or governmental rule, regulation or order applicable to it, do not and will not
contravene any provision of, or constitute a default under, any indenture,
mortgage, contract or other instrument to which it is a party or by which it is
bound, and the Leases and this Warrant Agreement constitute legal, valid and
binding agreements of the Company, enforceable in accordance with their
respective terms.

     (c)  Consents and Approvals. No consent or approval of, giving of notice
to, registration with, or taking of any other action in respect of any state,
Federal or other governmental authority or agency is required with respect to
the execution, delivery and performance by the Company of its obligations under
this Warrant Agreement, except for the filing of notices pursuant to Regulation
D under the 1933 Act and Section 25102(f) of the California Corporate Securities
Law, which filings will be affective by the time required thereby.

                                      -6-
<PAGE>

     (d)  Issued Securities. All issued and outstanding shares of Common Stock,
Preferred Stock or any other securities of the Company have been duly authorized
and validly issued and are fully paid and nonassessable. All outstanding shares
of Common Stock, Preferred Stock and any other securities were issued in full
compliance with all Federal and state securities laws. In addition:

          (i)    The authorized capital stock of the Company consists of (A)
40,000,000 shares of common stock, $.01 par value per share (the "Common
Stock"), 2,502,835 shares of which are issued and outstanding (including
1,377,835 shares issued pursuant to the 1994 Restricted Stock Plan of the
Company), (B) 5,000,000 shares of undesignated preferred stock, none of which
are issued or outstanding, (C) 4,922,299 shares of Series A Convertible
Preferred Stock, 4,853,334 shares of which are issued and outstanding, (D)
8,000,000 shares of Series B Convertible Preferred Stock, 7,447,223 shares of
which are issued or outstanding, (E) 1,000,000 shares, collectively, of Series C
Convertible Preferred Stock and Series D Convertible Preferred Stock, all of
which are issued and outstanding, and (G) 10,000,000 shares of Series E
Convertible Preferred Stock, all of which are issued or outstanding.

          (ii)   The Company has issued warrants to purchase 68,965 shares of
its Series A Convertible Preferred Stock at an average exercise price of $0.87
per share and 142,222 shares of its Series B Convertible Preferred Stock at an
average exercise price of $1.125 per share. The Company has reserved 4,000,000
shares of Common Stock for issuance pursuant to its 1995 Stock Option Plan. The
Company has reserved 3,040,000 shares of Common Stock for issuance pursuant to
its 1994 Restricted Stock Plan of which 1,377,835 shares are issued and
outstanding.

          (iii)  Except as stated in the Company's Charter and the Company's
Amended and Restated Registration Rights and Right of First Refusal Agreement,
no shareholder of the Company has preemptive rights to purchase new issuances of
the Company's capital stock.

     (e)  Insurance. The Company has in full force and effect insurance
policies, with extended coverage, insuring the Company and its property and
business against such losses and risks, and in such amounts, as are customary
for corporations engaged in a small business and similarly situated.

     (f)  Other Commitments to Register Securities. Except as set forth in this
Warrant Agreement, the Amended and Restated Registration Rights and Right of
First Refusal Agreement dated as of March 12, 1997 between the Company and
certain shareholders and the Stock Purchase Agreement dated September 2, 1994
between the Company and a certain Institution the Company is not, pursuant to
the term of any other agreement currently in existence, under any obligation to
register under the 1933 Act any of its presently outstanding securities or any
of its securities which may hereafter be issued.

     (g)  Exempt Transaction. Subject to the accuracy of the Warrantholder's
representations in Section 10 hereof, the issuance of the Common Stock upon
exercise of this Warrant will constitute a transaction exempt from (i) the
registration requirements of Section 5 of the 1933 Act, in reliance upon Section
4(2) thereof, and (ii) the qualification requirements of the California
Corporate Securities Law, in reliance upon Section 25102(f) thereof.

                                      -7-
<PAGE>

     (h)  Compliance with Rule 144. At the written request of the Warrantholder,
who proposes to sell Common Stock issuable upon the exercise of the Warrant in
compliance with Rule 144 promulgated by the Securities and Exchange Commission,
the Company shall furnish to the Warrantholder, within ten days after receipt of
such request, a written statement confirming the Company's compliance with the
filing requirements of the Securities and Exchange Commission as set forth in
such Rule, as such Rule may be amended from, time to time.

10.  REPRESENTATIONS AND COVENANTS OF THE WARRANTHOLDER.

     This Warrant Agreement has been entered into by the Company m reliance upon
the following representations and covenants of the Warrantholder.

     (a)  Investment Purpose. The right to acquire Common Stock or the Common
Stock issuable upon exercise of the Warrantholder's rights contained herein will
be acquired for investment and not with a view to the sale or distribution of
any part thereof, and the Warrantholder has no present intention of selling or
engaging in any public distribution of the same except pursuant to a
registration or exemption.

     (b)  Private Issue. The Warrantholder understands (i) that the Common Stock
issuable upon exercise of this Warrant is not registered under the 1933 Act or
qualified under applicable state securities laws on the ground that the issuance
contemplated by this Warrant Agreement will be exempt from the registration and
qualifications requirements thereof, and (ii) that the Company's reliance on
such exemption is predicated on die representations set forth in this Section
10.

     (c)  Disposition of Warrantholder's Rights. In no event will the
Warrantholder make a disposition of any of its rights to acquire Common Stock or
Common stock issuable upon exercise of such rights unless and until (i) it shall
have notified the Company of the proposed disposition, and (ii) if requested by
the Company, it shall have furnished the Company with an opinion of counsel
(which counsel may either be inside or outside counsel to the Warrantholder)
satisfactory to lie Company and its counsel to the effect that (A) appropriate
action necessary for compliance with the 1933 Act has been taken, or (B) an
exemption from the registration requirements of the 1933 Act is available.
Notwithstanding the foregoing, the restrictions imposed upon the transferability
of any of its rights to acquire Common Stock or Common Stock issuable on the
exercise of such rights do not apply to transfers from the beneficial owner of
any of the aforementioned securities to its nominee or from such nominee to its
beneficial owner, and shall terminate as to any particular share of Common Stock
when (1) such security shall have been effectively registered under the 1993 Act
and sold by the holder thereof in accordance with such registration or (2) such
security shall have been sold without registration in compliance with Rule 144
under the 1933 Act, or (3) a letter shall have been issued to the Warrantholder
at its request by the staff of the Securities and Exchange Commission stating
that no action shall be recommended by such staff or taken by such Commission,
as the case may be, if such security is transferred without registration under
the 1933 Act in accordance with the conditions set forth in such letter or
ruling and such letter or ruling specifies that no subsequent restrictions on
transfer are required. Whenever the restrictions imposed hereunder shall
terminate, as hereinabove provided, the Warrantholder or holder of a share of
Common Stock then outstanding as to which such restrictions have terminated
shall be entitled to receive from the Company,

                                      -8-
<PAGE>

without expense: to such holder, one or more new certificates for the Warrant or
for such shares of Common Stock not bearing any restrictive legend.

     Notwithstanding anything to the contrary contained herein:

          (i)    The Warrantholder shall not sell or transfer or agree to sell
or transfer any rights to acquire shares of stock of the Company or any shares
of stock of the Company (collectively, the "Offered Shares"), unless in each
case the Warrantholder shall have first complied with this Section 10(c). The
Warrantholder shall deliver to the Company a written notice of any proposed or
intended sale of Offered Shares (the "Offer"), which Offer shall (a) identify
the Offered Shares, (b) describe the price and other terms upon which they are
to be sold or transferred, and the number or amount of the Offered Shares to be
sold or transferred, and (c) offer to sell to the Company all (but not less than
all) such Offered Shares. The Company shall have the right, for a period of five
(5) days following delivery of the Offer, to purchase or acquire, at a price and
upon the other terms specified in the Offer, any and all Offered Shares
described above. The Offer by its term shall remain open and irrevocable for
such 5-day period.

          (ii)   To accept an Offer, the Company must deliver a written notice
to the Warrantholder prior to the end of the 5-day period of the Offer (the
"Notice of Acceptance"). If the Company does not accept the Offer, the
Warrantholder may sell the Offered Shares on the terms and conditions set forth
in the Offer for a period of forty-five (45) days following the end of the 5-day
period of the Offer.

          (iii)  Any Offered Shares not acquired by the Company or other persons
in accordance with this Section 10(c) may not be issued sold or exchanged until
they are again offered to the Company under the procedures specified in this
Agreement

          (iv)   The provisions of this Section 10(c) shall terminate upon the
closing of the Company's initial public offering of shares of Common Stock
pursuant to am effective registration statement under the Securities Act.

     (d)  Financial Risk. The Warrantholder has such knowledge and experience in
financial and business matters and in investing in companies similar to the
Company as to be capable of evaluating the merits and risks of its investment,
and has the ability to bear the economic risks of its investment.

     (e)  Authority. The Warrantholder has full power and authority to enter
into and to perform this Agreement in accordance with its terms. The
Warrantholder has not been organized, reorganized or recapitalized specifically
for the purpose of investing in the Company.

     (f)  Risk of No Registration. The Warrantholder understands that if the
Company does not register with the Securities and Exchange Commission pursuant
to Section 12 of the 1933 Act, or file reports pursuant to Section 15(d), of the
Securities Exchange Act of 1934 (the "1934 Act"), or if a registration statement
covering the securities under the 1933 Act is not in effect when it desires to
sell (i) the rights to purchase Common Stock pursuant to this Warrant Agreement,
or (ii) the Common Stock issuable upon exercise of the right to purchase, it may
be required to hold such securities for an indefinite period. The Warrantholder
also understands that any sale of its rights of the Warrantholder to purchase
Common Stock or Common Stock which might be made

                                      -9-
<PAGE>

by it in reliance upon Rule 144 under the 1933 Act may be made only in
accordance with the terms and conditions of that Rule.

11.  TRANSFERS.

     (a)  Subject to the tam and conditions contained in Section 10 hereof, this
Warrant Agreement and all rights hereunder are transferable in whole or in part
by the Warrantholder and any successor transferee, provided, however, in no
event shall the number of transfers of the rights and interests in all of the
Warrants exceed three (3) transfers. The transfer shall be recorded on the books
of the Company upon receipt by the Company of a notice of transfer in the form
attached hereto as Exhibit II (the "Transfer Notice"), at its principal offices
and the payment to the Company of all transfer taxes and other governmental
charges imposed on such transfer.

     (b)  Legends. Each certificate or agreement representing rights to acquire
shares of Common Stock shall bear a legend substantially in the following form:

          "The securities represented by this certificate have not
          been registered under the Securities Act of 1933, as
          amended, and may not be offered, sold or otherwise
          transferred, pledged or hypothecated unless and until such
          shares are registered under such Act, or an opinion of
          counsel satisfactory to the Company is obtained to the
          effect that such registration is not required."

     The foregoing legend shall be removed from the certificates representing
any Restricted Shares, at the request of the holder thereof, at such time as
they become eligible for resale pursuant to Rule 144 under the Securities Act.

     (c)  If any of the provisions set forth in this Agreement are violated, the
Company shall not be required (i) to transfer on its books any of the rights to
acquire shares of Common Stock, or (ii) to treat as owner of such rights to
acquire shares of Common Stock or to pay dividends to any transferee to whom any
such rights to acquire shares of Common Stock shall have been so sold or
transferred.

12.  MISCELLANEOUS

     (a)  Effective Date. The provisions of this Warrant Agreement shall be
construed and dull be given effect in all respects as if it had bow executed and
delivered by the Company on the date hereof. This Warrant Agreement shall be
binding upon any successors or assigns of the Company.

     (b)  Attorney's Fees. In any litigation, arbitration or court proceeding
between the Company and the Warrantholder relating hereto, the prevailing party
shall be entitled to attorneys' fees and expenses and all costs of proceedings
incurred in enforcing this Warrant Agreement.

     (c)  Governing Law. This Warrant Agreement shall be governed by and
construed for all purposes under and in accordance with the laws of the State of
California.

                                      -10-
<PAGE>

     (d)  Counterparts. This Warrant Agreement may be executed in two or more
counterparts, each of which shall be deemed an original, but all of which
together shall constitute one and the same instrument.

     (e)  Notices. Any notice required or permitted hereunder shall be governed
in writing and shall be deemed effectively given upon personal delivery,
facsimile transmission (provided that the original is sent by personal delivery
or mail as hereinafter set forth) or seven (7) days after deposit in the United
States mail, by registered or certified mail, addressed (i) to the Warrantholder
at 100 Drakes Landing Road, Suite 260, Greenbrae, CA 94904 with a copy to
William S. Veatch, Esq., c/o Cooley, Godward, Castro, Huddleson & Tatum, Five
Palo Alto Square, 3000 El Camino Real, Palo Alto, CA 94306-2155 and (ii) to the
Company at 45 Moulton Street,, Cambridge, MA 02138, (and/or if by facsimile,
(617) 876-0866), c/o Chief Financial Officer or at such other address as any
such party may subsequently designate by written notice to the other party.

     (f)  Remedies. In the event of any default hereunder, the non-defaulting
party may proceed to protect and enforce its rights either by suit in equity
and/or by action at law, including but not limited to an action for damages as a
result of any such default, and/or an action for specific performance for any
default where Warrantholder will not have an adequate remedy at law and where
damages will not be readily ascertainable.

     (g)  No Impairment of Rights. The Company will not, by amendment of its
Charter or through any other means, avoid or seek to avoid the observance or
performance of any of the term of this Warrant, but will at all times in good
faith assist in the carrying out of all such terms and in the taking of all such
actions as may be necessary or appropriate in order to protect the rights of the
Warrantholder against impairment. Any and all costs incurred by the Company in
assisting the Warrantholder in the protection of the Warrantholder's rights
shall be paid for, or reimbursed, by the Warrantholder.

     (h)  Survival. The representations, warranties, covenants and conditions of
the respective parties contained herein or made pursuant to this Warrant
Agreement shall survive the execution and delivery of this Warrant Agreement.

     (i)  Severability. In the event any one or more of the provisions of this
Warrant Agreement shall for any reason be held invalid, illegal or
unenforceable, the remaining provisions of this Warrant Agreement shall be
unimpaired and the invalid, illegal or unenforceable provision shall be replace
by a mutually acceptable valid, legal and enforceable provision, which comes
closest to the intention of the parties underlying the invalid, illegal or
unenforceable provision.

     (j)  Amendments. Any provision of this Warrant Agreement may be amended by
a written instrument signed by the Company and by the Warrantholder.

     (k)  Additional Documents. The Company, upon execution of this Warrant
Agreement shall provide the Warrantholder with certified resolutions with
respect to the representations, warranties and covenants set forth in
subparagraphs (a) through (d), (f) and (g) of Section 9 above. The Company shall
also supply such other documents as the Warrantholder may from time to time
reasonably request.

                                      -11-
<PAGE>

     IN WITNESS WHEREOF, the parties hereto have cause this Warrant Agreement to
be executed by its officers thereunto duly authorized as of the Effective Date.

                                        COMPANY:

                                        ONTOGENY, INC.

                                        By:    /s/ George Eldridge
                                               ---------------------------------

                                        Name:  George Eldridge
                                               ---------------------------------

                                        Title: Vice President of Finance
                                               ---------------------------------

                                        WARRANTHOLDER:

                                        LIGHTHOUSE CAPITAL PARTNERS, L.P.

                                        By:  LIGHTHOUSE MANAGEMENT
                                             PARTNERS, L.P., its general partner

                                        By:  LIGHTHOUSE CAPITAL PARTNERS,
                                             INC., its general partner

                                        By:    /s/ Gwill E. York
                                               ---------------------------------

                                        Name:  Gwill E. York
                                               ---------------------------------

                                        Title: Managing Director
                                               ---------------------------------

                                     -12-
<PAGE>

                                   EXHIBIT I

                              NOTICE OF EXERCISE

To:  __________________________________

(1)  The undersigned Warrantholder hereby elects to purchase _____________shares
     of the Common Stock of __________, pursuant to the terms of the Warrant
     Agreement dated the ____ day of __________, 19__ (the "Warrant Agreement")
     between ________________________ and the Warrantholder, and tenders
     herewith payment of the purchase price for such shares in full.

(2)  In exercising its rights to purchase the Common Stock of ____________, the
     undersigned hereby confirms and acknowledges the investment representations
     and warranties made in Section 10 of the Warrant Agreement.

(3)  Please issue a certificate or certificates representing said shares of
     Common Stock in the name of the undersigned or in such other name as is
     specified below.

___________________________________________
(Name)

___________________________________________
(Address)

Warrantholder:

By:    ____________________________________

Title: ____________________________________

Date:  ____________________________________

                          ACKNOWLEDGMENT OF EXERCISE

     The undersigned __________________, hereby acknowledge receipt of the
"Notice of Exercise" from _____________ to purchase ________ shares of the
Common Stock of _________________, pursuant to the terms of the Warrant
Agreement, and further acknowledges that _______ shares remain subject to
purchase under the terms of the Warrant Agreement.

                                              Company:

                                              By:    ________________________

                                              Title: ________________________

                                      -13-
<PAGE>

                                              Date:__________________________

                                      -14-
<PAGE>

                           NET ISSUE ELECTION NOTICE

To:  _____________________________________________________       Date:

_____________________

     The undersigned hereby elects under Section 3 to surrender the right to
purchase _____________ shares of Common Stock pursuant to this Warrant Agreement
The certificate(s) for such shares issuable upon such net issue election shall
be issued in the name of the undersigned or as otherwise indicated below:

                                        ----------------------------------------
                                        Signature

                                        ----------------------------------------
                                        Name for Registration

                                        ----------------------------------------
                                        Mailing Address

                                      -15-
<PAGE>

                                  EXHIBIT II

                                TRANSFER NOTICE

     (To transfer or assign the foregoing Warrant Agreement execute this form
     and supply required information. Do not use this form to purchase shares.)

     FOR VALUE RECEIVED, the foregoing Warrant Agreement and all rights
evidenced thereby are hereby transferred and assigned to _____________________
                                                            (Please Print)

___________________________ whose address is ___________________________________

________________________________________________________________________________

               Dated: ________________________________________

               Holder's Signature: ___________________________

               Holder's Address: _____________________________

                                      -16-
<PAGE>

                                  EXHIBIT III

                   Copy of the Certificate of Incorporation

                                      -17-<PAGE>

                                                                   Exhibit 10.57

THESE SECURITIES HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS
AMENDED (THE "SECURITIES ACT"), OR ANY STATE SECURITIES LAWS. THEY MAY NOT BE
SOLD OR OFFERED FOR SALE, PLEDGED OR HYPOTHECATED IN THE ABSENCE OF AN EFFECTIVE
REGISTRATION STATEMENT RELATED THERETO OR AN OPINION OF COUNSEL (WHICH MAY BE
COUNSEL FOR THE COMPANY) REASONABLY SATISFACTORY TO THE COMPANY THAT SUCH
REGISTRATION IS NOT REQUIRED UNDER THE SECURITIES ACT.

                                      No.

                          STOCK SUBSCRIPTION WARRANT

                          To Purchase Common Stock of

                        ONTOGENY, INC. (the "Company")

                  DATE OF INITIAL ISSUANCE:  November 21, 1997

          THIS CERTIFIES THAT for value received, MM VENTURES or its registered
assigns (hereinafter called the "Holder") is entitled to purchase from the
Company, at any time during the Term of this Warrant, One Thousand Three Hundred
Fifty (1,350) shares of common stock, $.01 par value, of the Company (the
"Common Stock"), at the Warrant Price, payable as provided herein.  The exercise
of this Warrant shall be subject to the provisions, limitations and restrictions
herein contained, and may be exercised in whole or in part.

SECTION 1.    Definitions.
              -----------

          For all purposes of this Warrant, the following terms shall have the
meanings indicated:

          Common Stock - shall mean and include the Company's authorized Common
          ------------
Stock, $.01 par value, as constituted at the date hereof.

          Exchange Act - shall mean the Securities Exchange Act of 1934, as
          ------------
amended from time to time.

          Securities Act - the Securities Act of 1933, as amended.
          --------------

          Term of this Warrant - shall mean the period beginning on the date of
          --------------------
initial issuance hereof and ending on November 21, 2002, subject to the
provisions of Section 2.3 below.

          Warrant Price - $2.50 per share, subject to adjustment in accordance
          -------------
with Section 5 hereof.

          Warrants - this Warrant and any other Warrant or Warrants issued in
          --------
connection with a Commitment Letter dated September 16, 1997 executed by the
Company and Transamerica Business Credit Corporation (the "Commitment Letter")
to the original holder of this Warrant, or any transferees from such original
holder or this Holder.
<PAGE>

        Warrant Shares - shares of Common Stock purchased or purchasable by
        --------------
the Holder of this Warrant upon the exercise hereof.

SECTION 2.    Exercise of Warrant.
              -------------------

        2.1.  Procedure for Exercise of Warrant.  This Warrant may be
              ---------------------------------
exercised in whole or in part by the Holder at any time, or from time to time,
prior to the expiration of the Term.  To exercise this Warrant in whole or in
part (but not as to any fractional share of Common Stock), the Holder shall
deliver to the Company at its office referred to in Section 13 hereof at any
time and from time to time during the Term of this Warrant: (i) the Notice of
Exercise in the form attached hereto, (ii) cash, certified or official bank
chock payable to the order of the Company or wire transfer of funds to the
Company's account (or any combination of any of the foregoing) in the amount of
the Warrant Price for each share being purchased, and (iii) this Warrant.
Notwithstanding any provisions herein to the contrary, if the Current Market
Price (as defined in Section 5) is greater than the Warrant Price (at the date
of exercise, as set forth below), in lieu of exercising this Warrant as
hereinabove permitted, the Holder may elect to receive shares of Common Stock
equal to the value (as determined below) of this Warrant (or the portion thereof
being canceled) by surrender of this Warrant at the office of the Company
referred to in Section 13 hereof, together with the Notice of Exercise, in which
event the Company shall issue to the Holder that number of shares of Common
Stock computed using the following formula:

                              CS = WCS x (CMP-WP)
                                   --------------
                                      CMP

Where

        CS   equals the number of shares of Common Stock to be issued to the
             Holder

        WCS  equals the number of shares of Common Stock purchasable under the
             Warrant or, if only a portion of the Warrant is being exercised,
             the portion of the Warrant being exercised (at the date of
             exercise)

        CMP  equals the Current Market Price (at the date of exercise)

        WP   equals the Warrant Price (as adjusted to the date of exercise)

In the event of any exercise of the rights represented by this Warrant, a
certificate or certificates for the shares of Common Stock so purchased,
registered in the name of the Holder or such other name or names as may be
designated by the Holder, shall be delivered to the Holder hereof within a
reasonable time, not exceeding fifteen (15) days, after the rights represented
by this Warrant shall have been so exercised; and, unless this Warrant has
expired, a new Warrant representing the number of shares (except a remaining
fractional share), if any, with respect to which this Warrant shall not then
have been exercised shall also be issued to the Holder hereof within such time.
The person in whose name any certificate for shares of Common Stock is issued
upon exercise of this Warrant shall for all purposes be deemed to have become
the holder of record of such shares on the date on which the Notice of Exercise
and Warrant is delivered to the Company and payment of the Warrant Price and any
applicable taxes is made, irrespective of the date of delivery of such
certificate, except that, if the date of such surrender and payment is a

                                       2
<PAGE>

date when the stock transfer books of the Company are closed, such person shall
be deemed to have become the holder of such shares at the close of business on
the next succeeding date on which the stock transfer books are open.

     2.2. Transfer Restriction Legend.  Each certificate for Warrant Shares
          ---------------------------
shall bear the following legend (and any additional legend required by (i) any
applicable state securities laws and (ii) any securities exchange upon which
such Warrant Shares may, at the time of such exercise, be listed) on the face
thereof unless at the time of exercise such Warrant Shares shall be registered
under the Securities Act:

          "The shares represented by this certificate have not been
          registered under the Securities Act of 1933, as amended,
          and may not be offered, sold or otherwise transferred,
          pledged or hypothecated unless and until such shares are
          registered under such Act, or an opinion of counsel
          satisfactory to the Company is obtained to the effect that
          such registration is not required."

Any certificate issued at any time in exchange or substitution for any
certificate bearing such legend (except a new certificate issued upon completion
of a public distribution under a registration statement of the securities
represented thereby) shall also bear such legend unless, in the opinion of
counsel for the holder thereof (which counsel shall be reasonably satisfactory
to counsel for the Company) the securities represented thereby are not, at such
time, required by law to bear such legend.

     2.3.  Acceleration of Term Upon Initial Public Offering.  Notwithstanding
           -------------------------------------------------
any provision to the contrary contained in this Warrant, the Holder's right to
exercise this Warrant shall expire, if not previously exercised, immediately
upon the closing of the issuance and sale of shares of Common Stock in the
Company's first public offering of securities for its own account pursuant to an
effective registration statement under the Securities Act (the "Initial Public
Offering"), provided that the underwriters request that the Holder exercise this
Warrant and provide at least fifteen (15) business days' opportunity to
exercise.

The Company shall notify the Holder if the Initial Public Offering is proposed,
within a reasonable period of time prior to the filing of a registration
statement.  Such notice shall contain such details of the proposed Initial
Public Offering as are reasonable in the circumstances and notice that this
Warrant is expected to expire upon closing thereof (provided such notice is
delivered at least fifteen (15) business days prior thereto).  If such closing
does not take place, the Company shall promptly notify the Holder that such
proposed transaction has been terminated.  Anything to the contrary in this
Warrant notwithstanding, the Holder may rescind any exercise promptly after such
notice of termination of the proposed transaction if the exercise occurred after
the Company notified the Holder that the Initial Public Offering was proposed or
if the exercise were otherwise precipitated by such proposed Initial Public
Offering.  In the event of such rescission, this Warrant will continue to be
exercisable on the same terms and conditions.

SECTION 3. Covenants as to Common Stock.  The Company covenants and agrees
           ----------------------------
that all shares of Common Stock that may be issued upon exercise of the rights
represented by this Warrant will, upon issuance, be validly issued, fully paid
and nonassessable, and free from all

                                       3
<PAGE>

taxes, liens and charges with respect to the issue thereof. The Company further
covenants and agrees that it will pay when due and payable any and all federal
and state taxes (not including taxes on or measured by the net income or capital
gains of the Holder) which may be payable in respect of the issue of this
Warrant or any Common Stock or certificates therefor issuable upon the exercise
of this Warrant. The Company further covenants and agrees that the Company will
at all times have authorized and reserved, free from preemptive rights, a
sufficient number of shares of Common Stock to provide for the exercise of the
rights represented by this Warrant. The Company further covenants and agrees
that if any shares of capital stock to be reserved for the purpose of the
issuance of shares upon the exercise of this Warrant require registration with
or approval of any governmental authority under any federal or state law before
such shares may he validly issued or delivered upon exercise, then the Company
will in good faith and as expeditiously as possible endeavor to secure such
registration or approval, as the case may be. If and so long as the Common Stock
issuable upon the exercise of this Warrant is listed on any national securities
exchange, the Company will, if permitted by the rules of such exchange, list and
keep listed on such exchange, upon official notice of issuance, all shares of
such Common Stock issuable upon exercise of this Warrant.

SECTION 4.  Adjustment of Number of Shares.  Upon each adjustment of the
            ------------------------------
Warrant Price as provided in Section 5, the Holder shall thereafter be entitled
to purchase, at the Warrant Price resulting from such adjustment, the number of
shares (calculated to the nearest tenth of a share) obtained by multiplying the
Warrant Price in effect immediately prior to such adjustment by the number of
shares purchasable pursuant hereto immediately prior to such adjustment and
dividing the product thereof by the Warrant Price resulting from such
adjustment.

SECTION 5.  Adjustment of Warrant Price.  The Warrant Price shall be subject
            ---------------------------
to adjustment from time to time as follows:

     (i)    If, at any time during the Term of this Warrant, the number of
shares of Common Stock outstanding is increased by a stock dividend payable in
shares of Common Stock or by a subdivision or split-up of shares of Common
Stock, then, following the record date fixed for the determination of holders of
Common Stock entitled to receive such stock dividend, subdivision or split-up,
the Warrant Price shall be appropriately decreased so that the number of shares
of Common Stock issuable upon the exercise hereof shall be increased in
proportion to such increase in outstanding shares.

     (ii)   If, at any time during the Term of this Warrant, the number of
shares of Common Stock outstanding is decreased by a combination of the
outstanding shares of Common Stock, then, following the record date for such
combination, the Warrant Price shall appropriately increase so that the number
of shares of Common Stock issuable upon the exercise hereof shall be decreased
in proportion to such decrease in outstanding shares.

     (iii)  All calculations under this Section 5 shall be made to the nearest
cent or to the nearest one tenth (l/10) of a share, as the case may be.

     (iv)   The Current Market Price at any date of one share of Common Stock
shall be deemed to be the average of the daily closing prices for the 15
consecutive business days ending on the third business day before the day in
question (as adjusted for any stock dividend, split,

                                       4
<PAGE>

combination or reclassification that took effect during such 15 business day
period). The closing price for each day shall be the last reported sales price
or, in case no such reported sales took place on such day, the average of the
last reported bid and asked prices, in either case on the principal national
securities exchange on which the Common Stock is listed or admitted to trading
or as reported by Nasdaq (or if the Common Stock is not at the time listed or
admitted for trading on any such exchange or if prices of the Common Stock are
not reported by Nasdaq then such price shall be equal to the average of the last
reported bid and asked prices on such day as reported by The National Quotation
Bureau Incorporated or any similar reputable quotation and reporting service, if
such quotation is not reported by The National Quotation Bureau Incorporated);
provided, however, that if the Common Stock is not traded in such manner that
the quotations referred to in this clause (v) are available for the period
required hereunder, the Current Market Price shall be determined in good faith
by the Board of Directors of the Company or, if such determination cannot be
made, by a nationally recognized independent investment banking firm selected by
the Board of Directors of the Company (or if such selection cannot be made, by a
nationally recognized independent investment banking firm selected by the
American Arbitration Association in accordance with its rules).

     (v)    Whenever the Warrant Price shall be adjusted as provided in Section
5, the Company shall prepare a statement showing the facts requiring such
adjustment and the Warrant Price that shall be in effect after such adjustment.
The Company shall cause a copy of such statement to be sent by mail, first class
postage prepaid, to each Holder of this Warrant at its, his or her address
appearing on the Company's records. Where appropriate, such copy may be given in
advance and may be included as part of the notice required to be mailed under
the provisions of subsection (viii) of this Section 5.

     (vi)   Adjustments made pursuant to clauses (i) and (ii) above shall be
made on the date such dividend, subdivision, split-up, combination or
distribution, as the case may be, is made, and shall become effective at the
opening of business on the business day next following the record date for the
determination of stockholders entitled to such dividend, subdivision, split-up,
combination or distribution.

     (vii)  In the event the Company shall propose to take any action of the
types described in clauses (i) or (ii) of this Section 5, the Company shall
forward, at the same time and in the same manner, to the Holder of this Warrant
such notice, if any, which the Company shall give to the holders of Common Stock
of the Company.

     (viii) In any case in which the provisions of this Section 5 shall require
that an adjustment shall become effective immediately after a record date for an
event, the Company may defer until the occurrence of such event issuing to the
Holder of all or any part of this Warrant which is exercised after such record
date and before the occurrence of such event the additional shares of capital
stock issuable upon such exercise by reason of the adjustment required by such
event over and above the shares of capital stock issuable upon such exercise
before giving effect to such adjustment exercise; provided, however, that the
Company shall deliver to such Holder a due bill or other appropriate instrument
evidencing such Holder's right to receive such additional shares upon the
occurrence of the event requiring such adjustment.

                                       5
<PAGE>

SECTION 6.  Ownership.
            ---------

       6.1. Ownership of This Warrant.  The Company may deem and treat the
            -------------------------
person in whose name this Warrant is registered as the holder and owner hereof
(notwithstanding any notations of ownership or writing hereon made by anyone
other than the Company) for all purposes and shall not be affected by any notice
to the contrary until presentation of this Warrant for registration of transfer
as provided in this Section 6.

       6.2. Transfer and Replacement.  This Warrant and all rights hereunder
            ------------------------
are transferable in whole or in part upon the books of the Company by the Holder
hereof in person or by duly authorized attorney, and a new Warrant or Warrants,
of the same tenor as this Warrant but registered in the name of the transferee
or transferees (and in the name of the Holder, if a partial transfer is
effected) shall be made and delivered by the Company upon surrender of this
Warrant duly endorsed, at the office of the Company referred to in Section 13
hereof. In the event of any purported transfer of this Warrant not in accordance
with the terms hereof, the Company shall not be required (i) to transfer on its
books any of the rights to acquire shares of Common Stock or Common Stock
issuable upon the exercise of such rights, or (ii) to treat as owner of such
rights to acquire shares of Common Stock or Common Stock issuable upon the
exercise of such rights. Upon receipt by the Company of evidence reasonably
satisfactory to it of the loss, theft or destruction, and, in such case, of
indemnity or security reasonably satisfactory to it, and upon surrender of this
Warrant if mutilated, the Company will make and deliver a new Warrant of like
tenor, in lieu of this Warrant; provided that if the Holder hereof is an
instrumentality of a state or local government or an institutional holder or a
nominee for such an instrumentality or institutional holder an irrevocable
agreement of indemnity by such Holder shall be sufficient for all purposes of
this Section 6, and no evidence of loss or theft or destruction shall be
necessary. This Warrant shall be promptly cancelled by the Company upon the
surrender hereof in connection with any transfer or replacement. Except as
otherwise provided above, in the case of the loss, theft or destruction of a
Warrant, the Company shall pay all expenses, taxes (not including taxes on or
measured by the net income or capital gains of the Holder) and other charges
payable in connection with any transfer or replacement of this Warrant, other
than stock transfer taxes (if any) payable in connection with a transfer of this
Warrant, which shall be payable by the Holder. Notwithstanding anything to the
contrary herein, Holder will not transfer this Warrant and the rights hereunder
except in compliance with federal and state securities laws.

SECTION 7.   Mergers, Consolidation, Sales.  In the case of any proposed
             -----------------------------
consolidation or merger of the Company with another entity, or the proposed sale
of all or substantially all of its assets to another person or entity, or any
proposed reorganization or reclassification of the capital stock of the Company,
then, as a condition of such consolidation, merger, sale, reorganization or
reclassification, lawful and adequate provision shall be made whereby the Holder
of this Warrant shall thereafter have the right to receive upon the basis and
upon the terms and conditions specified herein, in lieu of the shares of the
Common Stock of the Company immediately theretofore purchasable hereunder, such
shares of stock, securities or assets as may (by virtue of such consolidation,
merger, sale, reorganization or reclassification) be issued or payable with
respect to or in exchange for the number of shares of such Common Stock
purchasable hereunder immediately before such consolidation, merger, sale,
reorganization or reclassification.  In any such case appropriate provision
shall be made with respect to the rights and interests of the

                                       6
<PAGE>

Holder of this Warrant to the end that the provisions hereof shall thereafter be
applicable as nearly as may be, in relation to any shares of stock, securities
or assets thereafter deliverable upon the exercise of this Warrant.

SECTION 8.  Notice of Dissolution or Liquidation.  In case of any
            ------------------------------------
distribution of the assets of the Company in dissolution or liquidation (except
under circumstances when the foregoing Section 7 shall be applicable), the
Company shall give notice thereof to the Holder hereof and shall make no
distribution to shareholders until the expiration of twenty (20) days from the
date of mailing of the aforesaid notice and, in any case, the Holder hereof may
exercise this Warrant within twenty (20) days from the date of the giving of
such notice, and all rights herein granted not so exercised within such thirty-
day period shall thereafter become null and void.

SECTION 9.  Notice of Extraordinary Dividends.  If the Board of Directors of
            ---------------------------------
the Company shall declare any dividend or other distribution on its Common Stock
except out of earned surplus or by way of a stock dividend payable in shares of
its Common Stock, the Company shall mail notice thereof to the Holder hereof not
less than twenty (20) days prior to the record date fixed for determining
shareholders entitled to participate in such dividend or other distribution, and
the Holder hereof shall not participate in such dividend or other distribution
unless this Warrant is exercised prior to such record date.  The provisions of
this Section 9 shall not apply to distributions made in connection with
transactions covered by Section 7.

SECTION 10. Fractional Shares.  Fractional shares shall not be issued upon
            -----------------
the exercise of this Warrant but in any case where the Holder would, except for
the provisions of this Section 10, be entitled under the terms hereof to receive
a fractional share upon the complete exercise of this Warrant, the Company
shall, upon the exercise of this Warrant for the largest number of whole shares
then called for, pay a sum in cash equal to the excess of the Current Market
Price over the Warrant Price for such fractional share.

SECTION 11. Special Arrangements of the Company.  The Company covenants and
            -----------------------------------
agrees that during the Term of this Warrant, unless otherwise approved by the
Holder of this Warrant.

     11.1.  Will Reserve Shares.  The Company will reserve and set apart and
            -------------------
have available for issuance at all times, free from preemptive or other
preferential rights, the number of shares of authorized but unissued Common
Stock deliverable upon the exercise of this Warrant.

     11.2.  Will Not Amend Certificate.  The Company will not amend its
            --------------------------
Certificate of Incorporation to eliminate as an authorized class of capital
stock that class denominated as "Common Stock" on the date hereof.

     11.3.  Will Bind Successors.  This Warrant shall be binding upon any
            --------------------
corporation or other person or entity succeeding to the Company by merger,
consolidation or acquisition of all or substantially all of the Company's
assets.

SECTION 12. Representations and Covenants of the Holder.  This Warrant has
            -------------------------------------------
been entered into by the Company in reliance upon the following representations
and covenants of the Holder:

     (a)    Investment Purpose.  The right to acquire Common Stock or the Common
Stock issuable upon exercise of the Holder's rights contained herein will be
acquired for investment

                                       7
<PAGE>

and not with a view to the sale or distribution of any part thereof, and the
Holder has no present intention of selling or engaging in any public
distribution of the same except pursuant to a registration or exemption.

     (b)    Private Issue.  The Holder understands (i) that the Common Stock
issuable upon exercise of this Warrant is not registered under the Securities
Act or qualified under applicable state securities laws on the ground that the
issuance contemplated by this Warrant will be exempt from registration and
qualifications requirements, and (ii) that the Company's reliance on such
exemption is predicated on the representations set forth in this Section 12.

     (c)    Disposition of Holder's Rights.  In no event will the Holder make a
disposition of any of its rights to acquire Common Stock or Common Stock
issuable upon exercise of such rights unless and until (i) it shall have
notified the Company of the proposed disposition, and (ii) if requested by the
Company, it shall have furnished the Company with an opinion of counsel (which
counsel may either be inside or outside counsel to the Warrantholder)
satisfactory to the Company and its counsel to the effect that (a) appropriate
action necessary for compliance with the Securities Act has been taken, or (B)
an exemption from the registration requirements of the Securities Act is
available.  Notwithstanding the foregoing, the restrictions imposed upon the
transferability of any of its rights to acquire Common Stock or Common Stock
issuable on the exercise of such rights do not apply to transfers from the
beneficial owner of any of the aforementioned securities to its nominee or from
such nominee to its beneficial owner, and shall terminate as to any particular
share of Common Stock when (1) such security shall have been effectively
registered under the Securities Act and sold by the holder thereof in accordance
with such registration or (2) such security may be sold without registration in
compliance with Rule 144 under the Securities Act, or (3) a letter shall have
been issued to the Holder at the request by the staff of the Securities and
Exchange Commission or a ruling shall have been issued to the Holder at its
request by such Commission stating that no action shall be recommended by such
staff or taken by such commission, as the case may be, if such security is
transferred without registration under the Securities Act in accordance with the
conditions set forth in such letter or ruling and such letter or ruling
specifies that no subsequent restrictions on transfer are required.  Whenever
the restrictions imposed hereunder shall terminate as hereinabove provided the
Holder or holder of a share of Common Stock then outstanding as to which such
restrictions have terminated shall be entitled to receive from the Company,
without expense to such holder, one or more new certificates for the Warrant or
for such shares of Common Stock not bearing any restrictive legend.

     (d)    Financial Risk.  The Holder has such knowledge and experience in
financial and business matters and in investing in companies similar to the
Company as to be capable of evaluating the merits and risk of its investment,
and has the ability to bear the economic risks of its investment.

     (e)    Authority.  The Holder has full power and authority to enter into
and to perform this Agreement in accordance with its terms. The Holder has not
been organized, reorganized or recapitalized specifically for the purpose of
investing in the Company .

     (f)    Risk of No Registration.  The Holder understands that if the Company
does not register with the Securities and Exchange Commission pursuant to
Section 12 of the Securities

                                       8
<PAGE>

Act, or file reports pursuant to Section 15(d) of the Securities Exchange Act of
1934, or if a registration statement covering the securities under the
Securities Act is not in effect when it desires to sell (i) the rights to
purchase Common Stock pursuant to this Warrant, or (ii) the Common Stock
issuable upon exercise of the right to purchase, it may be required to hold such
securities for an indefinite period. The Holder also understands that any sale
of its rights to purchase Common Stock or Common Stock which may be made by it
in reliance upon Rule 144 under the Securities Act may be made only in
accordance with the terms and conditions of that Rule.

SECTION 13.  Notices.  Any notice or other document required or permitted to
             -------
be given or delivered to the Holder shall be delivered at, or sent by certified
or registered mail to, the Holder at Meier Mitchell & Company, 4 Orinda Way,
Suite 200-B, Orinda, California 94563 or to such other address as shall have
been furnished to the Company in writing by the Holder.  Any notice or other
document required or permitted to be given or delivered to the Company shall be
delivered at, or sent by certified or registered mail to, the Company at 45
Moulton Street, Cambridge, Massachusetts 02138, Attention: Vice President,
Finance with a copy to Hale and Dorr LLP, 60 State Street, Boston, Massachusetts
02109, Attention: Mark G. Borden, Esq. or to such other address as shall have
been furnished in writing to the Holder by the Company.  Any notice so addressed
and mailed by registered or certified mail shall be deemed to be given when so
mailed.  Any notice so addressed and otherwise delivered shall be deemed to be
given when actually received by the addressee.

SECTION 14.  No Rights as Stockholder; Limitation of Liability.  This Warrant
             -------------------------------------------------
shall not entitle the Holder to any of the rights of a shareholder of the
Company except upon exercise in accordance with the terms hereof.  No provision
hereof, in the absence of affirmative action by the Holder to purchase shares of
Common Stock, and no mere enumeration herein of the rights or privileges of the
Holder, shall give rise to any liability of the Holder for the Warrant Price
hereunder or as a shareholder of the Company, whether such liability is asserted
by the Company or by creditors of the Company.

SECTION 15.  Law Governing.  THE VALIDITY, INTERPRETATION, AND ENFORCEMENT OF
             -------------
THIS WARRANT SHALL BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH THE, LAWS OF
THE STATE OF ILLINOIS WITHOUT GIVING EFFECT TO THE CONFLICT OF LAW PRINCIPLES
THEREOF.

SECTION 16.  Miscellaneous.  This Warrant and any provision hereof may be
             -------------
changed, waived, discharged or terminated only by an instrument in writing
signed by the Company and the Holder (or any respective successor in interest
thereof).  The headings in this Warrant are for purposes of reference only and
shall not affect the meaning or construction of any of the provisions hereof.

     IN WITNESS WHEREOF, the Company has caused this Warrant to be signed by its
duly authorized officer this __day of November, 1997.

[CORPORATE SEAL]                           ONTOGENY, INC.

                                           By:__________________________________

                                       9
<PAGE>

                                           Title:_______________________________

MM VENTURES

By:________________________________
Name:
Title:

                                       10
<PAGE>

                          FORM OF NOTICE OF EXERCISE

               [To be signed only upon exercise of the Warrant]

                   TO BE EXECUTED BY THE REGISTERED HOLDER
                        TO EXERCISE THE WITHIN WARRANT

     The undersigned hereby exercises the right to purchase __________ shares of
Common Stock which the undersigned is entitled to purchase by the terms of the
within Warrant according to the conditions thereof, and herewith

[check one]              [_]   makes payment of $  therefor; or

                         [_]   directs the Company to issue _____ shares, and to
                               withhold _____ shares in lieu of payment of the
                               Warrant.

All shares to be issued pursuant hereto shall be issued in the name of and the
initial address of such person to be entered on the books of the Company shall
be:

     The shares are to be issued in certificates of the following denominations:

     The Holder confirms and acknowledges the investment representations made in
Section 12 of the Warrant.

                              __________________________________________________
                              [Type Name of Holder]

                              By:_______________________________________________

                              Title:_______________________________

Dated: _________________

                                       11
<PAGE>

                               FORM OF ASSIGNMENT
                                    (ENTIRE)

              [To be signed only upon transfer of entire Warrant]

                    TO BE EXECUTED BY THE REGISTERED HOLDER
                         TO TRANSFER THE WITHIN WARRANT

     FOR VALUE RECEIVED ________________________ hereby sells, assigns and
transfers unto _______________________ all rights of the undersigned under and
pursuant to the within Warrant, and the undersigned does hereby irrevocably
constitute and  appoint ________________________, Attorney to transfer the said
Warrant on the books of the Company, with full power of substitution.

                              ____________________________________________
                              [Type Name of Holder]

                              By:_________________________________________

                              Title:______________________________________

Dated:

NOTICE

     The signature to the foregoing Assignment must correspond to the name as
written upon the face of the within Warrant in every particular, without
alteration or enlargement or any change whatsoever.

Acknowledged and accepted:

_______________________________________
[Type name of assignee]

                                       12
<PAGE>

                               FORM OF ASSIGNMENT
                                   (PARTIAL)

              [To he signed only upon partial transfer of Warrant]

                    TO BE EXECUTED BY THE REGISTERED HOLDER
                         TO TRANSFER THE WITHIN WARRANT

     FOR VALUE RECEIVED _____________________ hereby sells, assigns and
transfers unto _________________________ (i) the rights of the undersigned to
purchase ____ shares of Common Stock under and pursuant to the within Warrant,
and (ii) on a non-exclusive basis, all other rights of the undersigned under and
pursuant to the within Warrant, it being understood that the undersigned shall
retain, severally (and not jointly) with the transferee(s) named herein, all
rights assigned on such non exclusive basis. The undersigned does hereby
irrevocably constitute and appoint __________________________ Attorney to
transfer the said Warrant on the books of the Company, with full power of
substitution.

                              __________________________________________
                              [Type Name of Holder]

                              By:_______________________________________

                              Title:____________________________________

Dated: __________________

NOTICE

     The signature to the foregoing Assignment must correspond to the name as
written upon the face of the within Warrant in every particular, without
alteration or enlargement or any change whatsoever.

Acknowledged and accepted:

______________________________
[Type name of assignee]

                                       13

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00003-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00003-of-00352.parquet"}]]