Document:

Exhibit 10.45

 

STEMONIX,
INC.

2015 STOCK OPTION PLAN

 

Section
1

DEFINED TERMS

 

In
addition to the other definitions contained herein, the following definitions shall apply:

 

1.1
Award. The term “Award” shall mean any award or benefit granted in accordance with the terms of the
Plan. Awards under the Plan may be in the form of Incentive Stock Options and/or Non-qualified Stock Options. The terms and conditions
of the Award shall be set forth in a Stock Option Agreement (as defined below).

 

1.2
Board. The term “Board” shall mean the Board of Directors of the Company.

 

1.3
Cause. “Cause” shall mean (a) the Eligible Individual’s violation of any provision of any noncompetition,
confidentiality or other written agreement with the Company; (b) an illegal or negligent action by the Eligible Individual that
materially and adversely affects the Company; (c) the Eligible Individual’s failure or refusal to perform his/her duties
(except when prevented by reason of illness or disability); or (d) conviction of the Eligible Individual of a felony involving
moral turpitude.

 

1.4
Change in Control. The term “Change in Control” shall mean:

 

	 	(a)	the
    acquisition by any person or group deemed a person under Sections 3(a)(9) and 13(d)(3) of the Exchange Act (other than the
    Company and its subsidiaries as determined immediately prior to that date) of beneficial ownership, directly or indirectly
    (with beneficial ownership determined as provided in Rule 13d-3, or any successor rule, under the Exchange Act), of a majority
    of the total combined voting power of all classes of Stock of the Company having the right under ordinary circumstances to
    vote at an election of the Board, if such person or group deemed a person prior to such acquisition was not a beneficial owner
    of at least five percent (5%) of such total combined voting power of the Company;
	 	 	 
	 	(b)	the
    merger or consolidation of the Company with another corporation or other entity where (i) shareholders of the Company immediately
    prior to such merger or consolidation would not beneficially own following such merger or consolidation shares entitling such
    shareholders to a majority of all votes (without consolidation of the rights of any class of stock to elect directors by a
    separate class vote) to which all shareholders of the surviving corporation would be entitled in the election of directors,
    or (ii) where the members of the Board, immediately prior to such merger or consolidation, would not, immediately after such
    merger or consolidation, constitute a majority of the board of directors of the surviving corporation; or
	 	 	 
	 	(c)	the
    sale of all or substantially all of the assets of the Company.

 

    	 

     

    

 

1.5
Code. The term “Code” shall mean the Internal Revenue Code of 1986, as amended. A reference to any provision
of the Code shall include reference to any successor provision of the Code.

 

1.6
Company. The term “Company” shall mean StemoniX, Inc., a Minnesota corporation.

 

1.7
Covered Shares. The term “Covered Shares” shall mean the number of shares of Stock that an Eligible
Individual may purchase pursuant to an Option.

 

1.8
Eligible Individual. The term “Eligible Individual” shall mean (a) any employee, prospective employee,
or officer of the Company, (b) members of the Board, (c) consultants and advisors to the Company, and (d) employees of any Related
Company. All Eligible Individuals must be natural persons who provide bona fide services to the Company or a Related Company.
An Award may be granted to an Eligible Individual prior to the date the Eligible Individual performs services for the Company
or Related Company, provided that such Award shall not become vested prior to the date the Eligible Individual first performs
such services.

 

1.9
Exchange Act. The term “Exchange Act” shall mean the Securities Act of 1934, as amended.

 

1.10
Exercise Price. The term “Exercise Price” shall mean the exercise price of each Option granted under
Section 4 established by the Board and determined by any reasonable method established by the Board at the time the Option is
granted. Options granted pursuant to Section 4 of the Plan shall not have an Exercise Price of less than 100% of the Fair Market
Value of the Company’s Stock on the date the Option is granted.

 

1.11
Fair Market Value. The term “Fair Market Value” of a share of Stock on a given date shall mean the fair
market value of the Stock as determined in good faith by the Board.

 

1.12
Incentive Stock Option. The term “Incentive Stock Option” or “ISO” shall mean an
Option that is intended to satisfy the requirements of Section 422(b) of the Code.

 

1.13
Non-Qualified Stock Option. The term “Non-Qualified Stock Option” or “NSO” shall
mean an Option that is not intended to satisfy the requirements applicable to an “incentive stock option” described
in Section 422(b) of the Code.

 

1.14
Option. The term “Option” or “Stock Option” shall mean an ISO or NSO granted pursuant
to the Plan. The grant of an Option entitles the Eligible Individual to purchase shares of Stock at an Exercise Price established
by the Board.

 

1.15
Plan. The term “Plan” shall mean this StemoniX, Inc. 2015 Stock Option Plan.

 

1.16
Related Company. The term “Related Company” shall mean any corporation other than the Company and any
partnership, joint venture or other entity in which the Company owns, directly or indirectly, at least a 20% beneficial ownership
interest. A Related Company includes a subsidiary of the Company and an unbroken chain of corporations beginning with the Company
if each of the corporations other than the last corporation in the unbroken chain owns 50% or more of the voting stock in one
of the other corporations in such chain.

 

    	2

     

    

 

1.17
Stock. The term “Stock” shall mean shares of common stock of the Company.

 

1.18
Stock Option Agreement. The term “Stock Option Agreement” or “Agreement” shall mean
any written agreement evidencing the terms and conditions of an ISO or NSO granted under the Plan. Each Agreement shall be subject
to the terms and conditions of the Plan.

 

Section
2

PURPOSE

 

The
Plan has been established by the Company to (a) attract and retain individuals eligible to participate in the Plan; (b) motivate
Eligible Individuals, by means of appropriate incentives, to achieve long-range goals; (c) provide incentive compensation opportunities
that are competitive with those of other similar companies; and (d) further align Eligible Individuals’ interests with those
of the Company’s shareholders through compensation that is based on the Stock, and thereby promote the long-term financial
interest of the Company and any Related Company, including the growth in value of the Company’s equity and enhancement of
long-term shareholder return.

 

Section
3

PARTICIPATION

 

Subject
to the terms and conditions of the Plan, the Board may determine and designate, from time to time, Eligible Individuals who will
be granted one or more Awards under the Plan. In its sole discretion and without shareholder approval, the Board may grant to
an Eligible Individual any Award or Awards permitted under the provisions of the Plan. Awards may be granted as alternatives to
or replacement of Awards outstanding under the Plan, or any other plan or arrangement of the Company or Related Company (including
a plan or arrangement of a business or entity, all or a portion of which is acquired by the Company or a Related Company). Only
employees are eligible to be granted Incentive Stock Options.

 

Section
4

STOCK OPTIONS

 

4.1
General. The grant of an Option entitles an Eligible Individual to purchase shares of Stock at an Exercise Price established
by the Board. Any Option awarded to Eligible Individuals under this Section 4 may be either an NSO or ISO, as determined in the
discretion of the Board. To the extent that any Stock Option does not qualify as an ISO, it shall constitute an NSO.

 

    	3

     

    

 

4.2
Option Awards. Subject to the following provisions, Options awarded under the Plan shall be in such form and shall have
such terms as the Board may determine and specify in a Stock Option Agreement entered into between the Eligible Individual and
the Company.

 

	 	(a)	Exercise
    of an Option. An Option shall be exercisable in accordance with such terms and conditions and during such periods as may
    be established by the Board.
	 	 	 
	 	(b)	Exercise
    Price. The Exercise Price of an Option granted under this Section 4 shall be established by the Board, except that the
    Exercise Price shall not be less than 100% of the Fair Market Value of a share of the Stock on the date of grant.
	 	 	 
	 	(c)	Payment
    of Option Exercise Price. The payment of the Exercise Price of an Option granted under this Section 4 shall be subject
    to the following:
	 	 	 	 
	 	 	(1)	Subject
    to the following provisions of this Section 4.2(c), the full Exercise Price for shares of Stock purchased upon the exercise
    of any Option shall be paid at the time of such exercise or such other time as approved by the Board.
	 	 	 	 
	 	 	(2)	Payment
    of the Exercise Price shall be made in such manner as the Board may provide in the Award, which may include cash and cash
    equivalents.
	 	 	 	 
	 	(d)	Settlement
    of Option. Shares of Stock delivered pursuant to the exercise of an Option shall be subject to such conditions, restrictions
    and contingencies as the Board, in its discretion, may establish in addition to such conditions, restrictions, and contingencies
    set forth in the Agreement.
	 	 	 
	 	(e)	Vesting.
    Eligible Individuals shall vest in all Options in accordance with the terms and conditions of the Agreement entered into by
    and between the Eligible Individual and the Company.
	 	 	 
	 	(f)	Option
    Term. The term of each Option shall be fixed by the Board. In the event that the Plan is terminated pursuant to terms
    and conditions of Section 8, the Plan shall remain in effect as long as any Awards under it are outstanding.
	 	 	 
	 	(g)	Termination
    of Employment. Following the termination of an Eligible Individual’s employment with the Company or a Related Company,
    any Option held by such Eligible Individual shall be exercisable to the extent determined by the Board and specified in the
    Stock Option Agreement. The Board may provide different post-termination exercise provisions with respect to termination of
    employment for different reasons.

 

    	4

     

    

 

	 	(h)	Incentive
    Stock Options. ISO grants may only be awarded to employees of the Company, a “parent corporation,” or a “subsidiary
    corporation” as those terms are defined in Sections 424(e) and 424(f) of the Code. In order for an employee to be eligible
    to receive an ISO grant, the employee must be employed by the Company, parent corporation, or subsidiary corporation during
    the period beginning on the date the Option is granted and ending on the day three (3) months prior to the date such Option
    is exercised. Notwithstanding the provisions of Section 4.2, no ISO shall (i) have an Exercise Price which is less than 100%
    of the Fair Market Value of the Stock on the date of the ISO Award, (ii) be exercisable more than ten (10) years after the
    ISO is awarded, or (iii) be awarded more than ten (10) years after the Effective Date of this Plan. No ISO awarded to an employee
    who owns more than 10% of the total combined voting power of all classes of stock of the Company, its “parent corporation”
    or any “subsidiary corporation” shall (i) have an Exercise Price of less than 110% of the Fair Market Value of
    the Stock on the date of the ISO Award or (ii) be exercisable more than five (5) years after the date of the ISO Award. To
    the extent that the aggregate fair market value (determined at the time of grant) of shares of Stock with respect to ISOs
    are exercisable for the first time by the employee during any calendar year, in combination with shares first exercisable
    under all other plans of the Company and any Related Company, exceeds $100,000, such Options shall be treated as NSOs.

 

Section
5

OPERATION AND ADMINISTRATION

 

5.1
General. The operation and administration of this Plan, including any Awards granted under this Plan, shall be subject
to the provisions of Section 5.

 

5.2
Effective Date. Subject to the approval of the shareholders of the Company, the Plan shall be effective as of [____________________],
2015 (the “Effective Date”) provided, however, that to the extent that Awards are granted under the Plan prior
to its approval by the shareholders of the Company, the Awards shall be subject to the approval of the Plan by the shareholders
of the Company. The term of the Plan shall be limited in duration to ten (10) years from the earlier of (a) the Effective Date
or (b) the date the Plan is approved by the Company’s shareholders.

 

5.3
Shares Subject to Plan. The shares of Stock for which Awards may be granted under this Plan shall be subject to the following:

 

	 	(a)	Subject
    to the following provisions of this Section 5.3, the maximum aggregate number of shares of Stock that may be issued and sold
    under the Plan shall be 560,250 shares. The shares of Stock may be authorized, but unissued, or reacquired Stock.
	 	 	 
	 	(b)	To
    the extent an Award terminates without having been exercised, or shares awarded are forfeited, such shares shall again be
    available issue under the Plan. Shares of Stock surrendered in payment of the Exercise Price and shares of Stock which are
    withheld in order to satisfy federal, state or local tax liability, shall not count against the maximum aggregate number of
    shares authorized to be issued pursuant to this Plan, and shall again be available for issuance pursuant to the terms of the
    Plan.

 

    	5

     

    

 

	 	(c)	In
    the event of any merger, reorganization, consolidation, recapitalization, stock dividend, stock split, combination or reverse
    stock split, spin-off, split-up, split-off, distribution of assets or other change in corporate structure affecting the Stock,
    a substitution or adjustment, as may be determined to be appropriate by the Board in its sole discretion, shall be made in
    the aggregate number of shares reserved for issuance under the Plan. However, no such adjustment shall exceed the aggregate
    value of any outstanding Award prior to such substitution or adjustment. In addition, upon an event described herein, the
    Board shall make an appropriate adjustment in the number of shares and the per-share option price of any options outstanding,
    but not yet exercised. The Board may make such other adjustments as it deems appropriate.

 

5.4
Securities Laws Restrictions. Issuance of shares of Stock under the Plan shall be subject to the following:

 

	 	(a)	If
    at any time the Board determines that the issuance of Stock under the Plan is or may be unlawful under the laws of any applicable
    jurisdiction, the right to exercise any Stock Option shall be suspended until the Board determines that such issuance is lawful.
    The Company shall have no obligation to effect any registration of qualification of the Stock under federal or state laws.
	 	 	 
	 	(b)	Any
    person exercising a Stock Option shall make such representations (including representations to the effect that such person
    will not dispose of the Stock so acquired in violation of federal and state securities laws) and furnish such information
    as may, in the opinion of counsel for the Company, be appropriate to permit the Company to issue the Stock in compliance with
    applicable federal and state securities laws. The Board may refuse to permit the exercise of a Stock Option until such representations
    and information have been provided.
	 	 	 
	 	(c)	The
    Company may place an appropriate legend evidencing any transfer restrictions on all shares of Stock issued under the Plan
    and may issue stop transfer instructions in respect thereof.

 

5.5
Tax Withholding. Each Eligible Individual shall, no later than the date as of which the value of an Award first becomes
includible in such person’s gross income for applicable tax purposes, pay, pursuant to such arrangements as the Company
may establish from time to time, any federal, state, local or other taxes of any kind required by law to be withheld with respect
to the Award. The obligations of the Company under the Plan shall be conditional on such payment, and the Company (and, where
applicable, any Related Company), shall, to the extent permitted by law, have the right to deduct any such taxes from any payment
of any kind otherwise due to the Eligible Individual.

 

    	6

     

    

 

5.6
Payments. Awards may be settled in any of the methods described in Section 4.2(c). Any Award settlement may be subject
to such conditions, restrictions and contingencies as the Board shall determine. Each Related Company shall be liable for payment
of cash due under the Plan with respect to any Eligible Individual to the extent that such benefits are attributable to the services
rendered for that Related Company by the Eligible Individual. Any disputes relating to liability of a Related Company for cash
payments shall be resolved by the Board.

 

5.7
Transferability. Except as otherwise provided by the Board, Awards under the Plan may not be sold, pledged, assigned, hypothecated,
transferred, or disposed of in any manner. If the Board makes an Award transferable, the Stock Option Agreement shall set forth
such additional terms and conditions regarding transferability as the Board deems appropriate.

 

5.8
Form and Time of Elections. Unless otherwise specified herein, each election required or permitted to be made by any Eligible
Individual or other person entitled to benefits under the Plan, and any permitted modification, or revocation thereof, shall be
in writing filed with the Board at such times, in such form, and subject to such restrictions and limitations, not inconsistent
with the terms of the Plan, as the Board shall require.

 

5.9
Agreement With Company. Any Award under the Plan shall be subject to such terms and conditions, not inconsistent with the
Plan, as the Board shall, in its sole discretion, prescribe. The terms and conditions of any Award shall be reflected in a Stock
Option Agreement. A copy of the Stock Option Agreement shall be provided to the Eligible Individual, and the Board may, but need
not require, the Eligible Individual to sign the Stock Option Agreement.

 

5.10
Limitation of Implied Rights.

 

	 	(a)	Neither
    an Eligible Individual nor any other person shall, by reason of participation in the Plan, acquire any right in or title to
    any assets, funds or property of the Company or any Related Company whatsoever, including, without limitation, any specific
    funds, assets, or other property which the Company or any Related Company, in its sole discretion, may set aside in anticipation
    of a liability under the Plan. An Eligible Individual shall have only a contractual right to the Stock unsecured by any assets
    of the Company or any Related Company.
	 	 	 
	 	(b)	This
    Plan does not constitute a contract of employment, and selection as a Eligible Individual will not give the Eligible Individual
    the right to be retained in the employ of the Company or any Related Company, nor any right or claim to any future grants
    or to any benefit under the Plan, unless such right or claim has specifically accrued under the terms of the Plan. Except
    as otherwise provided in the Plan, no Award under the Plan shall confer upon an Eligible Individual any rights of a shareholder
    of the Company prior to the date on which the Eligible Individual fulfills all conditions for receipt of such rights, including
    exercising the option and paying the exercise price.

 

    	7

     

    

 

5.11
Termination for Cause. If the employment of an Eligible Individual is terminated by the Company or a Related Company for
Cause, then the Board shall have the right to cancel any vested but unexercised Options granted to the Eligible Individual under
the Plan.

 

5.12
Evidence. Evidence required of anyone under the Plan may be by certificate, affidavit, document or other information which
the person acting on it considers pertinent and reliable, and signed, made or presented by the proper party or parties.

 

Section
6

CHANGE IN CONTROL

 

In
the event of a Change in Control, all of the outstanding Stock Options awarded to an Eligible Individual under the Plan shall
become fully exercisable and vested, provided that the individual remains an Eligible Individual on the date of the Change in
Control.

 

The
Board shall have the right to cancel Awards in the event of a Change in Control, provided that in exchange for such cancellation,
the Eligible Individual shall receive a cash payment equal to the Change in Control consideration less the exercise price of the
Awards.

 

Section
7

BOARD

 

7.1
Administration. The Plan shall be administered by the Board. All determinations made by the Board pursuant to the provisions
of the Plan shall be final and binding on all persons, including the Company and Eligible Individuals.

 

7.2
Powers of Board. The Board shall have the following authority with respect to Awards under the Plan: to grant Awards; to
adopt, alter and repeal such administrative rules, guidelines and practices governing the Plan as it shall deem advisable; to
interpret the terms and provisions of the Plan and any Award granted under the Plan; and to otherwise supervise the administration
of the Plan. In particular, and without limiting its authority and powers, the Board shall have the authority:

 

	 	(a)	to
    determine whether and to what extent any Award or combination of Awards will be granted hereunder;
	 	 	 
	 	(b)	to
    select the Eligible Individuals to whom Awards will be granted;
	 	 	 
	 	(c)	to
    determine the number of shares of Stock to be covered by each Award granted hereunder subject to the limitations contained
    herein;
	 	 	 
	 	(d)	to
    determine the terms and conditions of any Award granted hereunder, including, but not limited to, any vesting or other restrictions
    based on such performance objectives and such other factors as the Board may establish, and to determine whether the performance
    objectives and other terms and conditions of the Award are satisfied;

 

    	8

     

    

 

	 	(e)	to
    determine the treatment of Awards upon the Eligible Individual’s retirement, disability, death, termination for cause
    or other termination of employment or service;
	 	 	 
	 	(f)	to
    amend the terms of any Award, prospectively or retroactively; provided, however, that no amendment shall impair the rights
    of the Eligible Individual without his or her written consent; and
	 	 	 
	 	(g)	to
    determine the Fair Market Value of Stock, in good faith, as of any date.

 

Determinations
by the Board under the Plan relating to the form, amount, and terms and conditions of Awards need not be uniform, and may be made
selectively among Eligible Individuals who receive Awards under the Plan, whether or not such Eligible Individuals are similarly
situated.

 

7.3
Delegation by Board. Except to the extent prohibited by applicable law or the applicable rules of a stock exchange, the
Board may delegate all or any portion of its responsibilities and powers to any one or more of its members or any other person
or persons selected by it. Any such delegation may be revoked by the Board at any time.

 

7.4
Information to be Furnished to Board. The Company and any Related Company shall furnish the Board with such data and information
as it determines may be required for it to discharge its duties. The records of the Company and any Related Company as to an Eligible
Individual’s employment, termination of employment, leave of absence, reemployment and compensation shall be conclusive
on all persons unless determined to be incorrect. Eligible Individuals and other persons entitled to benefits under the Plan must
furnish the Board such evidence, data or information as the Board considers desirable to carry out the terms of the Plan.

 

7.5
Non-Liability of Board. No member of the Board, nor any officer or employee of the Company acting on behalf of the Board,
shall be personally liable for any action, determination or interpretation taken or made with respect to the Plan, and all members
of the Board and all officers or employees of the Company acting on its behalf shall, to the extent permitted by law, be fully
indemnified and protected by the Company with respect to any such action, determination or interpretation.

 

Section
8

AMENDMENT AND TERMINATION

 

The
Board may, at any time, amend or terminate the Plan, provided that no amendment or termination may, in the absence of written
consent to the change by any affected Eligible Individual (or, if the Eligible Individual is not then living, the affected beneficiary),
adversely affect the rights of any Eligible Individual or beneficiary under any Award granted under the Plan prior to the date
such amendment is adopted by the Board; provided that adjustments made pursuant to Section 5.3(c) shall not be subject to the
foregoing limitations of this Section 8. An amendment shall be subject to approval by the Company’s shareholders only to
the extent required by applicable laws, regulations or rules of a stock exchange or similar entity.

 

    	9

     

    

 

Section
9

INVESTMENT PURPOSES

 

Unless
a registration statement under the Securities Act of 1933, as amended (the “Act”) is in effect with respect
to Stock to be purchased upon exercise of Options to be granted under the Plan, the Company shall require that the Eligible Individual
agree with and represent to the Company in writing that he or she is acquiring such shares of Stock for the purpose of investment
and with no present intention to transfer, sell or otherwise dispose of such shares of Stock other than by transfers which may
occur by will or by the laws of descent and distribution, and no shares of Stock may be transferred unless, in the opinion of
counsel to the Company, such transfer would be in compliance with applicable securities laws. In addition, unless a registration
statement under the Act is in effect with respect to the Stock to be purchased under the Plan, each certificate representing any
shares of Stock issued to any Eligible Individual hereunder shall have endorsed thereon a legend in substantially the following
form:

 

THE
SHARES REPRESENTED BY THIS CERTIFICATE WERE ISSUED WITHOUT REGISTRATION UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “ACT”)
AND WITHOUT REGISTRATION UNDER ANY APPLICABLE STATE SECURITIES LAWS, IN RELIANCE UPON EXEMPTION(S) CONTAINED THEREIN. NO TRANSFER
OF THESE SHARES OR ANY INTEREST THEREIN MAY BE MADE EXCEPT PURSUANT TO EFFECTIVE REGISTRATION UNDER SAID LAWS UNLESS THE COMPANY
HAS RECEIVED AN OPINION OF COUNSEL SATISFACTORY TO IT THAT SUCH TRANSFER OR DISPOSITION DOES NOT REQUIRE REGISTRATION UNDER SAID
LAWS AND, FOR ANY SALES UNDER RULE 144 OF THE ACT, SUCH EVIDENCE AS IT SHALL REQUEST FOR COMPLIANCE WITH THAT RULE, OR APPLICABLE
STATE SECURITIES LAWS.

 

Section
10

GENERAL PROVISIONS

 

10.1
Stock Option Agreements. No Eligible Individual will have rights under an Award granted to such Eligible Individual unless
and until a Stock Option Agreement has been duly executed on behalf of the Company and, if required by the Company, by the Eligible
Individual.

 

10.2
No Limit on Other Compensation Arrangements. Nothing contained in the Plan shall prevent the Company or any Related Company
from adopting or continuing in effect other or additional compensation arrangements, and such arrangements may be either generally
applicable or applicable only in specific cases.

 

10.3
Headings. The headings of the sections and subsections of this Plan are intended for the convenience of the parties only
and shall in no way be held to explain, modify, construe, limit, amplify or aid in the interpretation of the provisions hereof.

 

    	10

     

    

 

10.4
Beneficiaries. An Eligible Individual may, from time to time, name any beneficiary or beneficiaries (who may be named contingently
or successively) to whom any benefit under the Plan may be paid or transferred in case of death. Each designation will revoke
all prior designations, shall be in a form prescribed by the Board, and will be effective only when filed by the Eligible Individual
in writing with the Board during his or her lifetime. In the absence of any such designation, benefits outstanding at the Eligible
Individual’s death shall be paid or transferred to his or her estate. There shall be no third party beneficiaries of or
to this Plan. Any beneficiary of the Eligible Individual shall have only a claim to such benefits as may be determined to be payable
hereunder, if any, and shall not, under any circumstances other than the right to claim such benefits, be deemed a third party
beneficiary of or to this Plan.

 

10.5
Governing Law. The Plan, and all agreements hereunder, shall be construed in accordance with and governed by the laws of
the State of Minnesota, except to the extent preempted by federal law, without regard to the principles of comity or the conflicts
of law provisions of any jurisdiction.

  

	 	STEMONIX, INC.
	 	 	 
	 	By:	/s/
    Yung-Ping Yeh
	 	Name:	Yung-Ping
    Yeh
	 	Its:
    	Chief
    Executive Officer
	 	 	 
	 	Dated:
    	May
    4, 2015

 

Approved
by Board of Directors on May 4, 2015.

Approved
by Shareholders on May 4, 2015.

 

    	11Exhibit 10.46

 

FIRST
AMENDMENT TO

STEMONIX, INC.

2015 STOCK OPTION PLAN

  

THIS
FIRST AMENDMENT TO STEMONIX, INC. 2015 STOCK OPTION PLAN (this “Amendment”) is made effective as of February 17,
2017.

 

RECITALS

 

A.
StemoniX, Inc., a Minnesota corporation (the “Company”) adopted that certain 2015 Stock Option Plan (the “Plan”)
as of May 4, 2015.

 

B.
Section 8 of the Plan permits the Board of Directors of the Company (the “Board”) to amend the Plan.

 

C.
By written action dated February 17, 2017, the Board approved an amendment to the Plan to increase to 677,338 the number of shares
issuable under the Plan.

 

NOW,
THEREFORE, in consideration of the foregoing and for other good and valuable consideration, the receipt and sufficiency of
which are hereby acknowledged, the Plan is hereby amended as follows:

 

1.
Shares Subject to Plan. Section
5.3(a) of the Plan is hereby amended and restated in its entirety to read as follows:

 

Subject
to the following provisions of this Section 5.3, the maximum aggregate number of shares of Stock that may be issued and sold under
the Plan shall be 677,338 shares. The shares of Stock may be authorized, but unissued, or reacquired Stock.

 

2.
Remaining Terms. Except as expressly
set forth in this Amendment, all other terms and provisions of the Plan shall remain in full force and effect.

 

3.
Governing Law. This Amendment and
the rights of the parties hereunder will be governed by, interpreted, and enforced in accordance with the internal laws, without
regard to the law pertaining to choice or conflict of laws, of the State of Minnesota.

 

4.
Method of Execution. This Amendment
may be executed by pdf or other facsimile.

 

5.
Binding Effect. This Amendment
shall be binding upon the Company and recipients of awards under the Plan, and their respective successors and permitted assigns.

 

[SIGNATURE
PAGE FOLLOWS]

 

    	 

    	 

    

 

IN
WITNESS WHEREOF, the undersigned has executed this Amendment as of the date first written above.

 

	 	StemoniX,
    Inc.
	 	 	 
	 	By:	/s/
    Yung-Ping Yeh
	 	Name:	Yung-Ping
    Yeh
	 	Its:
    	Chief
    Executive Officer

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00320-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00320-of-00352.parquet"}]]