Document:

EXHIBIT 10.10

RELIV' INTERNATIONAL, INC.            148671-2006943                    HH/as/ph

                               LINE OF CREDIT NOTE

                                                             St. Louis, Missouri
$1,000,000.00 and interest                                    November 15, 2002

      On Demand, and if no demand be made, then on the 1st day of December,
2003, the undersigned promise(s) to pay to the order of SOUTWEST BANK OF ST.
LOUIS, St. Louis, Missouri, 63110-3498 (herein called "Bank") at its office in
said City or to such other place as the holder hereof shall from time to time
designate, the principal sum of ONE MILLION AND 00/100 Dollars, or the then
outstanding and unpaid principal balance of the sums advanced hereunder together
with accrued interest. Each borrowing hereunder shall bear interest from the
date advanced by Bank at the rate of 0.00% in excess of Southwest Bank of St.
Louis' Prime Rate, to be adjusted with each change thereto, payable monthly, and
shall be calculated on the actual number of days on the basis of a year of 360
days. This note shall bear interest after maturity whether by demand,
acceleration or otherwise at the rate of five percent (5 %) over the stated
rate. As used herein, the term "Prime Rate" shall mean the rate of interest
announced from time to time by the Bank as its "Prime Rate", such term being
used only as a reference rate and not necessarily representing the lowest rate
charged to any customer of the Bank. In the event the Bank ceases to use the
term "Prime Rate" in setting a base rate for commercial loans, the term "Prime
Rate" as used herein shall be determined by reference to the rate used by the
Bank as its base rate of interest for commercial loans.

      Until the occurrence of any event of default herein described or any
default or any event which with the passage of time or giving of notice, or
both, would constitute a default under any agreements listed below, or the
maturity of this note, whether by demand, acceleration or otherwise, the
undersigned may borrow and repay and re-borrow such amounts, hereunder, except
that each advance or repayment will be in a minimum amount of ONE THOUSAND AND
00/100 Dollars or any multiples thereof, but not exceeding the maximum amount
set forth above. Unless otherwise instructed by the undersigned, all advances
under this note will be credited to checking account No.058726 carried on the
books of Bank in the name of Reliv' International, Inc. and the undersigned
agrees that Bank may make advances at its discretion, upon oral instructions of
any of the undersigned or upon occurrence of an overdraft in said checking
account. If any payment of principal or interest under this Note is not paid
within thirty (30) days after the payment is due, then the Undersigned shall pay
to Bank a late charge of ten percent (10%) of such payment, but in any event not
less than Ten Dollars ($10.00).

      Upon the occurrence of any of the following events of default: failure of
the undersigned to make any payments required hereunder or comply with any of
the provisions contained in this note or any other obligations of the
undersigned to Bank or to any other party, and the continuation of such default
following applicable notice and cure rights, if any, or if any instrument,
document, agreement or guaranty delivered in connection with any of the
indebtedness evidenced by this note or otherwise owed to Bank, shall not be, or
shall cease to be, enforceable in accordance with its terms or be contested by
any obligor thereunder, or death, dissolution, termination of existence,
insolvency, failure to pay debts as they mature, appointment of a receiver of
any part of the property of, an assignment for the benefit of creditors, or the
commencement of any proceedings under bankruptcy or insolvency laws, by or
against any of the undersigned, then or at any time thereafter, this note and
all other obligations of each of the undersigned to the Bank shall, at the
option of Bank, become due and payable without notice or

<PAGE>

demand and no further advances will thereafter be made by Bank under the terms
of this note. Furthermore, Bank reserves the right to offset without notice all
funds or other property held by Bank against matured debts owing to Bank by
undersigned. The undersigned will pay on demand all costs of collection, legal
expenses and attorney's fees incurred or paid in collecting or enforcing this
note including representation in any bankruptcy or insolvency proceedings and
whether or not any lawsuit is ever Filed with respect thereto. Each of the
undersigned hereby waives presentment, protest, demand, notice of dishonor or
default and consents to any and all renewals, extensions, and/or the release of
any collateral or party directly or indirectly liable for the payment hereof,
all without notice to and without affecting the liability of any of the
undersigned. As used herein "undersigned" shall mean each maker and each
endorser, and each jointly and severally, agrees to all the provisions hereof.
This note shall be governed by the laws of the State of Missouri without regard
to conflict of law principle and shall bind the undersigned and shall inure to
the benefit of the Bank and any holder hereof.

      In addition to all other rights and security of Bank, security for this
note and all other indebtedness owing to Bank:

Security Agreement dated 5/25/99 and 1/2/96 covering Accounts, Inventory and
Equipment.

      All payments hereunder shall be made in immediately available funds by
1:00 p.m. St. Louis, Missouri time on the day when due. If any payment of
principal or interest on this note, shall become due on a Saturday, Sunday or
any day on which the Bank is legally closed to business, such payment shall be
made on the next succeeding business day and such extension of time shall be
included in computing interest in connection with such payment.

      The rights and remedies of the Bank under this note are cumulative and are
not in lieu of, but are in addition to any other rights or remedies which the
Bank shall have under any other instrument, or at law or in equity.

      THE UNDERSIGNED HEREBY CONSENTS TO THE JURISDICTION OF ANY STATE COURT
LOCATED WITIIIN THE CITY OF ST. LOUIS OR ST. LOUIS COUNTY, MISSOURI OR FEDERAL
COURT IN THE EASTERN DISTRICT OF MISSOURI, EASTERN DIVISION. THE UNDERSIGNED
WAVES ANY OBJECTION TO JURISDICTION AND VENUE OF ANY ACTION INSTITUTED AGAINST
IT AS PROVIDED HEREIN AND AGREES NOT TO ASSERT ANY DEFENSE BASED ON LACK OF
JURISDICTION OR VENUE. THE UNDERSIGNED EURTHER AGREES NOT TO ASSERT AGAINST THE
BANK (EXCEPT BY WAY OF A DEFENSE OR COUNTERCLAIM IN A PROCEEDING INITIATED BY
THE BANK) ANY CLAIM OR OTHER ASSERTION OF LIABILITY WITH RESPECT TO THIS NOTE,
THE BANK'S CONDUCT OR OTHERWISE IN ANY JURSDICTION OTHER THAN THE FOREGOING
JURISDICTIONS.

      THE UNDERSIGNED HEREBY WAIVES ANY RIGHT TO TRIAL BY JURY (WHICH THE BANK
ALSO WAIVES) IN ANY ACTION, SUIT, PROCEEDING OR COUNTERCLAIM OF ANY KIND ARISING
OUT OF OR RELATING TO THIS NOTE, THE OBLIGATIONS OF THE UNDERSIGNED HEREUNDER OR
THE BANK'S CONDUCT IN RESPECT OF ANY OF THE FOREGOING.

                                        2

<PAGE>

      The following notice is given pursuant to Section 432.045 of the Missouri
Revised Statutes; nothing contained in such notice shall be deemed to limit or
modify the terms of this note. ORAL AGREEMENTS OR COMMITTMENTS TO LEND MONEY,
EXTEND CREDIT OR TO FOREBEAR FROM ENFORCING REPAYMENT OF A DEBT INCLUDING
PROMISES TO EXTEND OR RENEW SUCH DEBT ARE NOT ENFORCEABLE. TO PROTECT YOU
(BORROWER(S)) AND US (CREDITOR) FROM MISUNDERSTANDING OR DISAPPOINTMENT, ANY
AGREEMENTS WE REACH COVERING SUCH MATTERS ARE CONTAINED IN THIS WRITING, WHICH
IS THE COMPLETE AND EXCLUSIVE STATEMENT OF THE AGREEMENT BETWEEN US, EXCEPT AS
WE MAY LATER AGREE IN WRITING TO MODIFY IT.

      Signature(s) below constitutes execution of this note and acknowledgement
of receipt of a copy of note.

                                      RELIV' INTERNATIONAL, INC.

                                      By:  /s/ Robert L. Montgomery
                                          -------------------------
                                      Name:  Robert L. Montgomery
                                      Its:  President

                                      By:  /s/ Steven D. Albright
                                          -------------------------
                                      Name:  Steven D. Albright
                                      Its:  Controller

                                      Address:  P.O. Box 405
                                                Chesterfield, MO 63006-0405

                                       3EXHIBIT 4.9

                                 PROMISSORY NOTE

                                December 27, 2002

FOR VALUE RECEIVED, Discovery Laboratories, Inc. a corporation located at the
address stated below ("Maker") promises, jointly and severally if more than one,
to pay to the order of General Electric Capital Corporation or any subsequent
holder hereof (each, a "Payee") at its office located at 401 Merritt 7 Suite 23,
Norwalk, CT 06851 or at such other place as Payee or the holder hereof may
designate, the principal sum of Two Hundred Eighty-Four Thousand Six Hundred
Fifty-Seven-37/100 Dollars ($284,657.37), with interest on the unpaid principal
balance, from the date hereof through and including the dates of payment, at a
fixed interest rate of Twelve and Fifty-Hundredths percent (12.50%) per annum,
to be paid in lawful money of the United States, in Thirty-Six (36) consecutive
monthly installments of principal and interest as follows:

       Periodic
      Installment                        Amount
      -----------------------------------------

      Thirty-Five (35)                  9,396.26

each ("Periodic Installment") and a final installment which shall be in the
amount of the total outstanding principal and interest. The first Periodic
Installment shall be due and payable on January 1, 2003 and the following
Periodic Installments and the final installment shall be due and payable on the
same day of each succeeding month each, a "Payment Date"). Such installments
have been calculated on the basis of a 360-day year of twelve 30-day months.
Each payment may, at the option of the Payee, be calculated and applied on an
assumption that such payment would be made on its due date.

The acceptance by Payee of any payment which is less than payment in full of all
amounts due and owing at such time shall not constitute a waiver of Payee's
right to receive payment in full at such time or at any prior or subsequent
time.

The Maker hereby expressly authorizes the Payee to insert the date value is
actually given in the blank space on the face hereof and on all related
documents pertaining hereto.

This Note may be secured by a security agreement, chattel mortgage, pledge
agreement or like instrument (each of which is hereinafter called a "Security
Agreement").

Time is of the essence hereof. If any installment or any other sum due under
this Note or any Security Agreement is not received within ten (10) days after
its due date, the Maker agrees to pay, in addition to the amount of each such
installment or other sum, a late payment charge of five percent (5%) of the
amount of said installment or other sum, but not exceeding any lawful maximum.
If (i) Maker fails to make payment of any amount due hereunder within ten (10)
days after the same becomes due and payable; or (ii) Maker is in default under,
or fails to perform under any term or condition contained in any Security
Agreement, then the entire principal sum remaining unpaid, together with all
accrued interest thereon and any other sum payable under this Note or any
Security Agreement, at the election of Payee, shall immediately become due and
payable, with interest thereon at the lesser of eighteen percent (18%) per annum
or the highest rate not prohibited by applicable law from the date of such
accelerated maturity until paid (both before and after any judgment).

Notwithstanding anything to the contrary contained herein or in the Security
Agreement, Maker may not prepay in full or in part any indebtedness hereunder
without the express written consent of Payee in its sole discretion.

It is the intention of the parties hereto to comply with the applicable usury
laws; accordingly, it is agreed that, notwithstanding any provision to the
contrary in this Note or any Security Agreement, in no event shall this Note or
any Security Agreement require the payment or permit the collection of interest
in excess of the maximum amount permitted by applicable law. If any such excess
interest is contracted for, charged or received under this Note or any Security
Agreement, or if all of the principal balance shall be prepaid, so that under
any of such circumstances the

<PAGE>

amount of interest contracted for, charged or received under this Note or any
Security Agreement on the principal balance shall exceed the maximum amount of
interest permitted by applicable law, then in such event (a) the provisions of
this paragraph shall govern and control, (b) neither Maker nor any other person
or entity now or hereafter liable for the payment hereof shall be obligated to
pay the amount of such interest to the extent that it is in excess of the
maximum amount of interest permitted by applicable law, (c) any such excess
which may have been collected shall be either applied as a credit against the
then unpaid principal balance or refunded to Maker, at the option of the Payee,
and (d) the effective rate of interest shall be automatically reduced to the
maximum lawful contract rate allowed under applicable law as now or hereafter
construed by the courts having jurisdiction thereof. It is further agreed that
without limitation of the foregoing, all calculations of the rate of interest
contracted for, charged or received under this Note or any Security Agreement
which are made for the purpose of determining whether such rate exceeds the
maximum lawful contract rate, shall be made, to the extent permitted by
applicable law, by amortizing, prorating, allocating and spreading in equal
parts during the period of the full stated term of the indebtedness evidenced
hereby, all interest at any time contracted for, charged or received from Maker
or otherwise by Payee in connection with such indebtedness; provided, however,
that if any applicable state law is amended or the law of the United States of
America preempts any applicable state law, so that it becomes lawful for the
Payee to receive a greater interest per annum rate than is presently allowed,
the Maker agrees that, on the effective date of such amendment or preemption, as
the case may be, the lawful maximum hereunder shall be increased to the maximum
interest per annum rate allowed by the amended state law or the law of the
United States of America.

The Maker and all sureties, endorsers, guarantors or any others (each such
person, other than the Maker, an "Obligor") who may at any time become liable
for the payment hereof jointly and severally consent hereby to any and all
extensions of time, renewals, waivers or modifications of, and all substitutions
or releases of, security or of any party primarily or secondarily liable on this
Note or any Security Agreement or any term and provision of either, which may be
made, granted or consented to by Payee, and agree that suit may be brought and
maintained against any one or more of them, at the election of Payee without
joinder of any other as a party thereto, and that Payee shall not be required
first to foreclose, proceed against or exhaust any security hereof in order to
enforce payment of this Note. The Maker and each Obligor hereby waives
presentment, demand for payment, notice of nonpayment, protest, notice of
protest, notice of dishonor, and all other notices in connection herewith, as
well as filing of suit (if permitted by law) and diligence in collecting this
Note or enforcing any of the security hereof, and agrees to pay (if permitted by
law) all expenses incurred in collection, including Payee's actual attorneys'
fees. Maker and each Obligor agrees that fees not in excess of twenty percent
(20%) of the amount then due shall be deemed reasonable.

Maker hereby irrevocably authorizes and empowers the Prothonotary or Clerk, or
any attorney for any Court of record to appear for Maker in such Courts, at any
time, and confess a judgement against Maker, without process, in favor of any
holder hereof, without the filing of a declaration of default, with release of
errors, without stay of execution, for such amount as may appear from the face
hereof to be due hereunder (or, if such attorney so elects, for the amount which
may be due hereon as evidenced by an affidavit signed by a representative of
holder setting forth the amount then due) together with charges, attorney's fees
and costs as herein provided, and Maker hereby waives and releases all benefits
and relief from any and all appraisement, stay or exemption laws of any state,
now in force or hereafter to be passed. If a copy hereof, verified by an
affidavit, shall have been filed in said proceeding, it shall not be necessary
to file the original as a warrant of attorney. No single exercise of the
foregoing warrant and power to confess judgement shall be deemed to exhaust the
power, whether or not such exercise shall be held by any Court to be invalid,
voidable, or void, but the power shall continue undiminished and may be
exercised from time to time as often as the holder hereof shall elect, until all
sums payable or that may become payable hereunder by Maker have been paid in
full.

THE MAKER HEREBY UNCONDITIONALLY WAIVES ITS RIGHTS TO A JURY TRIAL OF ANY CLAIM
OR CAUSE OF ACTION BASED UPON OR ARISING OUT OF, DIRECTLY OR INDIRECTLY, THIS
NOTE, ANY OF THE RELATED DOCUMENTS, ANY DEALINGS BETWEEN MAKER AND PAYEE
RELATING TO THE SUBJECT MATTER OF THIS TRANSACTION OR ANY RELATED TRANSACTIONS,
AND/OR THE RELATIONSHIP THAT IS BEING ESTABLISHED BETWEEN MAKER AND PAYEE. THE
SCOPE OF THIS WAIVER IS INTENDED TO BE ALL ENCOMPASSING OF ANY AND ALL DISPUTES
THAT MAY BE FILED IN ANY COURT (INCLUDING, WITHOUT LIMITATION, CONTRACT CLAIMS,
TORT CLAIMS, BREACH OF DUTY CLAIMS, AND ALL OTHER COMMON LAW AND STATUTORY
CLAIMS.) THIS WAIVER IS IRREVOCABLE MEANING

<PAGE>

THAT IT MAY NOT BE MODIFIED EITHER ORALLY OR IN WRITING, AND THE WAIVER SHALL
APPLY TO ANY SUBSEQUENT AMENDMENTS, RENEWALS, SUPPLEMENTS OR MODIFICATIONS TO
THIS NOTE, ANY RELATED DOCUMENTS, OR TO ANY OTHER DOCUMENTS OR AGREEMENTS
RELATING TO THIS TRANSACTION OR ANY RELATED TRANSACTION. IN THE EVENT OF
LITIGATION, THIS NOTE MAY BE FILED AS A WRITTEN CONSENT TO A TRIAL BY THE COURT.

This Note and any Security Agreement constitute the entire agreement of the
Maker and Payee with respect to the subject matter hereof and supercedes all
prior understandings, agreements and representations, express or implied.

No variation or modification of this Note, or any waiver of any of its
provisions or conditions, shall be valid unless in writing and signed by an
authorized representative of Maker and Payee. Any such waiver, consent,
modification or change shall be effective only in the specific instance and for
the specific purpose given.

Any provision in this Note or any Security Agreement which is in conflict with
any statute, law or applicable rule shall be deemed omitted, modified or altered
to conform thereto.

                                        Discovery Laboratories, Inc.

/s/ David Kille                         By:    /s/ John G. Cooper
--------------------------------           -------------------------------------
(Witness)

David Kille                             Name:  John G. Cooper
(Print Name)

350 S. Main St., Suite 307
Doylestown, PA 18901                    Title: Senior VP, CFO
(Address)
                                        Federal Tax ID #: 94-3171943

                                        Address: 350 South Main St. Suite 307,
                                        Doylestown, Bucks County, PA 18901

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