Document:

EX-10.46

 Exhibit 10.46 

THE SECURITIES WHICH ARE THE SUBJECT OF THIS AGREEMENT HAVE NOT BEEN QUALIFIED WITH THE COMMISSIONER OF CORPORATIONS OF THE STATE OF CALIFORNIA AND THE
ISSUANCE OF SUCH SECURITIES OR THE PAYMENT OR RECEIPT OF ANY PART OF THE CONSIDERATION THEREFOR PRIOR TO SUCH QUALIFICATION IS UNLAWFUL, UNLESS THE SALE OF SECURITIES IS EXEMPT FROM QUALIFICATION BY SECTION 25100, 25102, OR 25105 OF THE CALIFORNIA
CORPORATIONS CODE. THE RIGHTS OF ALL PARTIES TO THIS AGREEMENT ARE EXPRESSLY CONDITIONED UPON SUCH QUALIFICATION BEING OBTAINED, UNLESS THE SALE IS SO EXEMPT. 

THE SECURITIES WHICH ARE THE SUBJECT OF THIS AGREEMENT HAVE BEEN ACQUIRED FOR INVESTMENT AND NOT WITH A VIEW TO, OR IN CONNECTION WITH, THE SALE OR
DISTRIBUTION THEREOF. NO SUCH SALE OR DISPOSITION MAY BE EFFECTED WITHOUT AN EFFECTIVE REGISTRATION STATEMENT RELATED THERETO OR AN OPINION OF COUNSEL SATISFACTORY TO THE COMPANY THAT SUCH REGISTRATION IS NOT REQUIRED UNDER THE SECURITIES ACT OF
1933. 
 HISTOGEN INC. 

STOCK OPTION AGREEMENT 

Histogen Inc. has granted to the Participant named in the Notice of Grant of Stock Option (the “Grant
Notice”) to which this Stock Option Agreement (the “Option Agreement”) is attached an option (the “Option”) to purchase certain shares of Stock upon the terms and
conditions set forth in the Grant Notice and this Option Agreement. The Option has been granted pursuant to and shall in all respects be subject to the terms and conditions of the Histogen Inc. 2007 Stock Plan (the
“Plan”), as amended to the Date of Grant, the provisions of which are incorporated herein by reference. By signing the Grant Notice, the Participant: (a) acknowledges receipt of, and represents that the
Participant has read and is familiar with the terms and conditions of, the Grant Notice, this Option Agreement and the Plan, (b) accepts the Option subject to all of the terms and conditions of the Grant Notice, this Option Agreement and the
Plan, and (c) agrees to accept as binding, conclusive and final all decisions or interpretations of the Board upon any questions arising under the Grant Notice, this Option Agreement or the Plan. 

 

	 	1.	 DEFINITIONS AND CONSTRUCTION. 

1.1 Definitions. Unless otherwise defined herein, capitalized terms shall have the meanings assigned to such terms in the Grant Notice
or the Plan. 
 1.2 Construction. Captions and titles contained herein are for convenience only and shall not affect the meaning or
interpretation of any provision of this Option Agreement. Except when otherwise indicated by the context, the singular shall include the plural and the plural shall include the singular. Use of the term “or” is not intended to be
exclusive, unless the context clearly requires otherwise. 

  
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	 	2.	 TAX CONSEQUENCES. 

2.1 Tax Status of Option. This Option is intended to have the tax status designated in the Grant Notice. 

(a) Incentive Stock Option. If the Grant Notice so designates, this Option is intended to be an Incentive Stock Option
within the meaning of Section 422(b) of the Code, but the Company does not represent or warrant that this Option qualifies as such. The Participant should consult with the Participant’s own tax advisor regarding the tax effects of this
Option and the requirements necessary to obtain favorable income tax treatment under Section 422 of the Code, including, but not limited to, holding period requirements. (NOTE TO PARTICIPANT: If the Option is exercised more than three
(3) months (or any shorter period specified in this Option Agreement) after the date on which you cease to be an Employee (other than by reason of your death or permanent and total disability as defined in Section 22(e)(3) of the Code),
the Option will be treated as a Nonstatutory Stock Option and not as an Incentive Stock Option to the extent required by Section 422 of the Code.) 

(b) Nonstatutory Stock Option. If the Grant Notice so designates, this Option is intended to be a Nonstatutory Stock
Option and shall not be treated as an Incentive Stock Option within the meaning of Section 422(b) of the Code. 
 2.2 ISO Fair Market
Value Limitation. If the Grant Notice designates this Option as an Incentive Stock Option, then to the extent that the Option (together with all Incentive Stock Options granted to the Participant under all stock option plans of the
Participating Company Group, including the Plan) becomes exercisable for the first time during any calendar year for shares having a Fair Market Value greater than One Hundred Thousand Dollars ($100,000), the portion of such options which exceeds
such amount will be treated as Nonstatutory Stock Options. For purposes of this Section 2.2, options designated as Incentive Stock Options are taken into account in the order in which they were granted, and the Fair Market Value of stock is
determined as of the time the option with respect to such stock is granted. If the Code is amended to provide for a different limitation from that set forth in this Section 2.2, such different limitation shall be deemed incorporated herein
effective as of the date required or permitted by such amendment to the Code. If the Option is treated as an Incentive Stock Option in part and as a Nonstatutory Stock Option in part by reason of the limitation set forth in this Section 2.2,
the Participant may designate which portion of such Option the Participant is exercising. In the absence of such designation, the Participant shall be deemed to have exercised the Incentive Stock Option portion of the Option first. Separate
certificates representing each such portion shall be issued upon the exercise of the Option. (NOTE TO PARTICIPANT: If the aggregate Exercise Price of the Option (that is, the Exercise Price multiplied by the Number of Option Shares) plus the
aggregate exercise price of any other Incentive Stock Options you hold (whether granted pursuant to the Plan or any other stock option plan of the Participating Company Group) is greater than $100,000, you should contact the Chief Financial Officer
of the Company to ascertain whether the entire Option qualifies as an Incentive Stock Option.) 

  
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	 	3.	 ADMINISTRATION. 

All questions of interpretation concerning the Grant Notice, this Option Agreement and the Plan shall be determined by the Board. All
determinations by the Board shall be final and binding upon all persons having an interest in the Option. Any Officer shall have the authority to act on behalf of the Company with respect to any matter, right, obligation, or election which is the
responsibility of or which is allocated to the Company herein, provided the Officer has apparent authority with respect to such matter, right, obligation, or election. 
  

	 	4.	 EXERCISE OF THE OPTION. 

4.1 Right to Exercise. Except as otherwise provided herein, the Option shall 

be exercisable on and after the Initial Vesting Date and prior to the termination of the Option (as provided in Section 6) in an amount
not to exceed the number of Vested Shares less the number of shares previously acquired upon exercise of the Option, subject to the Company’s repurchase rights set forth in Section 11. In no event shall the Option be exercisable for more
shares than the Number of Option Shares, as adjusted pursuant to Section 9. 
 4.2 Method of Exercise. Exercise of the Option
shall be by means of electronic or written notice (the “Exercise Notice”) in a form authorized by the Company. An electronic Exercise Notice must be digitally signed or authenticated by the Participant in such manner
as required by the notice and transmitted to the Company or an authorized representative of the Company (including a third-party administrator designated by the Company). In the event that the Participant is not authorized or is unable to provide an
electronic Exercise Notice, the Option shall be exercised by a written Exercise Notice addressed to the Company, which shall be signed by the Participant and delivered in person, by certified or registered mail, return receipt requested, by
confirmed facsimile transmission, or by such other means as the Company may permit, to the Company, or an authorized representative of the Company (including a third-party administrator designated by the Company). Each Exercise Notice, whether
electronic or written, must state the Participant’s election to exercise the Option, the number of whole shares of Stock for which the Option is being exercised and such other representations and agreements as to the Participant’s
investment intent with respect to such shares as may be required pursuant to the provisions of this Option Agreement. Further, each Exercise Notice must be received by the Company prior to the termination of the Option as set forth in Section 6
and must be accompanied by full payment of the aggregate Exercise Price for the number of shares of Stock being purchased. The Option shall be deemed to be exercised upon receipt by the Company of such electronic or written Exercise Notice and the
aggregate Exercise Price. 
 4.3 Payment of Exercise Price. 

(a) Forms of Consideration Authorized. Except as otherwise provided below, payment of the aggregate Exercise Price for
the number of shares of Stock for which the Option is being exercised shall be made (i) in cash or by check or cash equivalent, (ii) if permitted by the Company, by tender to the Company, or attestation to the ownership, of whole shares of
Stock owned by the Participant having a Fair Market Value not less than the ageregate Exercise Price, (iii) by means of a Cashless Exercise, as defined in Section 4.3(b), or (iv) by any combination of the foregoing. 

  
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 (b) Limitations on Forms of Consideration. 

(i) Tender of Stock. Notwithstanding the foregoing, the Option may not be exercised by tender to the Company, or attestation to the
ownership, of shares of Stock to the extent such tender or attestation would constitute a violation of the provisions of any law, regulation or agreement restricting the redemption of the Company’s stock. If required by the Company, the Option
may not be exercised by tender to the Company, or attestation to the ownership, of shares of Stock unless such shares either have been owned by the Participant for more than six (6) months or such other period, if any, required by the Company
(and not used for another option exercise by attestation during such period) or were not acquired, directly or-indirectly, from the Company. 

(ii) Cashless Exercise. A “Cashless Exercise” means the delivery of a properly executed notice together
with irrevocable instructions to a broker in a form acceptable to the Company providing for the assignment to the Company of the proceeds of a sale or loan with respect to some or all of the shares of Stock acquired upon the exercise of the Option
pursuant to a program or procedure approved by the Company (including, without limitation, through an exercise complying with the provisions of Regulation T as promulgated from time to time by the Board of Governors of the Federal Reserve System).
The Company reserves, at any and all times, the right, in the Company’s sole and absolute discretion, to establish, decline to approve, or terminate any such program or procedure, including with respect to the Participant notwithstanding that
such program or procedures may be available to others. 
 4.4 Tax Withholding. At the time the Option is exercised, in whole or in
part, or at any time thereafter as requested by the Company, the Participant hereby authorizes withholding from payroll and any other amounts payable to the Participant, and otherwise agrees to make adequate provision for (including by means of a
Cashless Exercise to the extent permitted by the Company), any sums required to satisfy the federal, state, local and foreign tax withholding obligations of the Participating Company Group, if any, which arise in connection with the Option. The
Company shall have no obligation to deliver shares of Stock until the tax withholding obligations of the Participating Company Group have been satisfied by the Participant. 

4.5 Certificate Registration. Except in the event the Exercise Price is paid by means of a Cashless Exercise, the certificate for the
shares as to which the Option is exercised shall be registered in the name of the Participant, or, if applicable, in the names of the heirs of the Participant. 

4.6 Restrictions on Grant of the Option and Issuance of Shares. The grant of the Option and the issuance of shares of Stock upon
exercise of the Option shall be subject to compliance with all applicable requirements of federal, state or foreign law with respect to such securities. The Option may not be exercised if the issuance of shares of Stock upon exercise would
constitute a violation of any applicable federal, state or foreign securities laws or other law or regulations or the requirements of any stock exchange or market system upon which the Stock may then be listed. In addition, the Option may not be
exercised unless (i) a registration statement under the Securities Act shall at the time of exercise of the Option be in effect with 

  
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respect to the shares issuable upon exercise of the Option or (ii) in the opinion of legal counsel to the Company, the shares issuable upon exercise of the Option may be issued in accordance
with the terms of an applicable exemption from the registration requirements of the Securities Act. THE PARTICIPANT IS CAUTIONED THAT THE OPTION MAY NOT BE EXERCISED UNLESS THE FOREGOING CONDITIONS ARE SATISFIED. ACCORDINGLY, THE PARTICIPANT MAY NOT
BE ABLE TO EXERCISE THE OPTION WHEN DESIRED EVEN THOUGH THE OPTION IS VESTED. The inability of the Company to obtain from any regulatory body having jurisdiction the authority, if any, deemed by the Company’s legal counsel to be necessary to
the lawful issuance and sale of any shares subject to the Option shall relieve the Company of any liability in respect of the failure to issue or sell such shares as to which such requisite authority shall not have been obtained. As a condition to
the exercise of the Option, the Company may require the Participant to satisfy any qualifications that may be necessary or appropriate, to evidence compliance with any applicable law or regulation and to make any representation or warranty with
respect thereto as may be requested by the Company. 
 4.7 Fractional Shares. The Company shall not be required to issue fractional
shares upon the exercise of the Option. 
  

	 	5.	 NONTRANSFERABILITY OF THE OPTION. 

During the lifetime of the Participant, the Option shall be exercisable only by the Participant or the Participant’s guardian or legal
representative. The Option shall not be subject in any manner to anticipation, alienation, sale, exchange, transfer, assignment, pledge, encumbrance, or garnishment by creditors of the Participant or the Participant’s beneficiary, except
transfer by will or by the laws of descent and distribution. Following the death of the Participant, the Option, to the extent provided in Section 7, may be exercised by the Participant’s legal representative or by any person empowered to
do so under the deceased Participant’s will or under the then applicable laws of descent and distribution. 
  

	 	6.	 TERMINATION OF THE OPTION. 

The Option shall terminate and may no longer be exercised after the first to occur of (a) the close of business on the
Option Expiration Date, (b) the close of business on the last date for exercising the Option following termination of the Participant’s Service as described in Section 7, or (c) a Change in Control to the extent provided in
Section 8. 
  

	 	7.	 EFFECT OF TERMINATION OF SERVICE. 

7.1 Option Exercisability. The Option shall terminate immediately upon the Participant’s termination of Service to the extent that
it is then unvested and shall be exercisable after the Participant’s termination of Service to the extent it is then vested only during the applicable time period as determined below and thereafter shall terminate. 

(a) Disability. If the Participant’s Service terminates because of the Disability of the Participant, the Option, to
the extent unexercised and exercisable for Vested Shares on the date on which the Participant’s Service terminated, may be exercised by the Participant (or the Participant’s guardian or legal representative) at any time prior to the
expiration of twelve (12) months after the date on which the Participant’s Service terminated, but in any event no later than the Option Expiration Date. 

  
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 (b) Death. If the Participant’s Service terminates because
of the death of the Participant, the Option, to the extent unexercised and exercisable for Vested Shares on the date on which the Participant’s Service terminated, may be exercised by the Participant’s legal representative or other person
who acquired the right to exercise the Option by reason of the Participant’s death at any time prior to the expiration of twelve (12) months after the date on which the Participant’s Service terminated, but in any event no later than
the Option Expiration Date. The Participant’s Service shall be deemed to have terminated on account of death if the Participant dies within three (3) months after the Participant’s termination of Service. 

(c) Other Termination of Service. If the Participant’s Service terminates for any reason, except Disability
or death, the Option, to the extent unexercised and exercisable for Vested Shares by the Participant on the date on which the Participant’s Service terminated, may be exercised by the Participant at any time prior to the expiration of ninety
(90) days after the date on which the Participant’s Service terminated, but in any event no later than the Option Expiration Date. 

7.2 Extension if Exercise Prevented by Law. Notwithstanding the foregoing, if the exercise of the Option within the applicable time
periods set forth in Section 7.1 is prevented by the provisions of Section 4.6, the Option shall remain exercisable until thirty (30) days after the date the Participant is notified by the Company that the Option is exercisable, but
in any event no later than the Option Expiration Date. 
  

	 	8.	 EFFECT OF CHANGE IN CONTROL. 

In the event of a Change in Control, the surviving, continuing, successor, or purchasing entity or parent thereof, as the case may be (the
“Acquiror”), may, without the consent of the Participant, assume or continue in full force and effect the Company’s rights and obligations under the Option or any portion thereof or substitute for the Option or
any portion thereof a substantially equivalent option for the Acquiror’s stock. For purposes of this Section, the Option shall be deemed assumed if, following the Change in Control, the Option confers the right to receive, subject to the terms
and conditions of the Plan and this Option Agreement, for each share of Stock subject to the Option immediately prior to the Change in Control, the consideration (whether stock, cash, other securities or property or a combination thereof) to which a
holder of a share of Stock on the effective date of the Change in Control was entitled; provided, however, that if such consideration is not solely common stock of the Acquiror, the Board may, with the consent of the Acquiror, provide for the
consideration to be received upon the exercise of the Option, for each share of Stock subject to the Option, to consist solely of common stock of the Acquiror equal in Fair Market Value to the per share consideration received by holders of Stock
pursuant to the Change in Control. In the event that the Acquiror fails to assume or substitute for this Option in connection with a Change in Control, and if the Participant has at least two full years of continuous Service as of the effective date
of the Change in Control, the Participant shall be fully and immediately vested in one hundred percent (100%) of the shares subject to this Option effective immediately prior to the consummation of the Change in Control, so long as the
Participant’s Service has not terminated prior to the effective date of the Change in Control. In the event that the Acquiror fails to assume or substitute for this Option in connection with a Change in Control, and if the Participant has less
than two full years of continuous Service as of the effective date of the Change in Control, the Participant shall be 

  
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vested in fifty percent (50%) of the shares subject to this Option that were not otherwise vested immediately prior to the consummation of the Change in Control, which vesting shall occur
effective immediately prior to the consummation of the Change in Control, so long as the Participant’s Service has not terminated prior to the effective date of the Change in Control. In the event that the Acquiror assumes or substitutes for
this Option in connection with a Change in Control, the Change in Control shall not change or affect the vested status of the shares subject to this Option. The exercise or vesting of any Option and any shares acquired upon the exercise thereof that
was permissible solely by reason of this Section shall be conditioned upon the consummation of the Change in Control. The Option shall terminate and cease to be outstanding effective as of the time of consummation of the Change in Control to the
extent that the Option is neither assumed or continued by the Acquiror in connection with the Change in Control nor exercised as of the effective date of the Change in Control. Notwithstanding the foregoing, shares acquired upon exercise of the
Option prior to the Change in Control and any consideration received pursuant to the Change in Control with respect to such shares shall continue to be subject to all applicable provisions of this Option Agreement except as otherwise provided
herein. 
  

	 	9.	 ADJUSTMENTS FOR CHANGES IN CAPITAL STRUCTURE. 

Subject to any required action by the shareholders of the Company, in the event of any change in the Stock effected without receipt of
consideration by the Company, whether through merger, consolidation, reorganization, reincorporation, recapitalization, reclassification, stock dividend, stock split, reverse stock split, split-up, split-off, spin-off, combination of shares, exchange of shares, or similar change in the capital structure of the Company, or in the event of payment of a dividend or
distribution to the shareholders of the Company in a form other than Stock (excepting normal cash dividends) that has a material effect on the Fair Market Value of shares of Stock, appropriate and proportionate adjustments shall be made in the
number, Exercise Price and kind of shares subject to the Option, in order to prevent dilution or enlargement of the Participant’s rights under the Option. For purposes of the foregoing, conversion of any convertible securities of the Company
shall not be treated as “effected without receipt of consideration by the Company.” Any fractional share resulting from an adjustment pursuant to this Section shall be rounded down to the nearest whole number and the Exercise Price shall
be rounded up to the nearest whole cent. In no event may the Exercise Price be decreased to an amount less than the par value, if any, of the stock subject to the Option. Such adjustments shall be determined by the Board, and its determination shall
be final, binding and conclusive. 
  

	 	10.	 RIGHTS AS A SHAREHOLDER, DIRECTOR, EMPLOYEE OR CONSULTANT. 

The Participant shall have no rights as a shareholder with respect to any shares covered by the Option until the date of the issuance of the
shares for which the Option has been exercised (as evidenced by the appropriate entry on the books of the Company or of a duly authorized transfer agent of the Company). No adjustment shall be made for dividends, distributions or other rights for
which the record date is prior to the date the shares are issued, except as provided in Section 9. If the Participant is an Employee, the Participant understands and acknowledges that, except as otherwise provided in a separate, written
employment agreement between a Participating Company and the Participant, the Participant’s employment is “at will” and is for no specified term. Nothing in this Option Agreement shall confer upon the Participant any right to continue
in the Service of a Participating Company or interfere in any way with any right of the Participating Company Group to terminate the Participant’s Service as a Director, an Employee or Consultant, as the case may be, at any time. 

  
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	 	11.	 REPURCHASE OPTION. 

11.1 Grant of Repurchase Option. In the event the Participant’s Service is terminated for any reason or no reason, with or without
cause, the Company shall have the right to repurchase the shares acquired upon exercise of this Option (the “Shares”) under the terms and subject to the conditions set forth in this Section (the “Repurchase
Option”). 
 11.2 Exercise of Repurchase Option. The Company may exercise the Repurchase Option by written notice
to the Participant within ninety (90) days after (a) termination of the Participant’s Service or (b) in the case of Shares issued upon exercise of this Option after termination of Service, within ninety (90) days after the
date of exercise. If the Company fails to give notice within such ninety (90) day period, the Repurchase Option shall terminate unless the Company and the Participant have extended the time for the exercise of the Repurchase Option. The
Repurchase Option may be exercised, if at all, for all or any portion of the Shares, as determined in the sole discretion of the Company. 

11.3 Payment for Shares and Return of Shares to Company. The purchase price per Share being repurchased by the Company shall be an
amount equal to the Fair Market Value of the Shares on the Participant’s date of termination of Service (the “Repurchase Price”). The Company shall pay the aggregate Repurchase Price to the Participant in cash on
or before the termination of the ninety (90) day period described in Section 11.2. The Shares being repurchased shall be delivered to the Company by the Participant at the same time as the delivery of the Repurchase Price to the
Participant. 
 11.4 Assignment of Repurchase Option. The Company shall have the right to assign the Repurchase Option at any time,
whether or not such option is then exercisable, to one or more persons as may be selected by the Company. 
 11.5 Ownership Change
Event. Upon the occurrence of an Ownership Change Event, any and all new, substituted or additional securities or other property to which the Participant is entitled by reason of the Participant’s ownership of Shares shall be immediately
subject to the Repurchase Option and included in the terms “Stock” and “Shares” for all purposes of the Repurchase Option with the same force and effect as the Shares immediately prior to the Ownership Change Event. While the
aggregate Repurchase Price shall remain the same after such Ownership Change Event, the Repurchase Price per Share upon exercise of the Repurchase Option following such Ownership Change Event shall be adjusted as appropriate. 

11.6 Termination of Vested Share Repurchase Option. The Repurchase Option shall terminate and be of no further force and effect upon the
existence of a public market for the class of shares subject to the Repurchase Option. A “public market” shall be deemed to exist if (i) such stock is listed on a national securities exchange (as that term is used
in the Exchange Act) or (ii) such stock is traded on the over-the-counter market and prices therefor are published daily on business days in a recognized financial
journal. 

  
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	 	12.	 RIGHT OF FIRST REFUSAL. 

12.1 Grant of Right of First Refusal. Except as provided in Section 12.7 and Section 17 below, in the event the Participant, the
Participant’s legal representative, or other holder of shares acquired upon exercise of the Option proposes to sell, exchange, transfer, pledge, or otherwise dispose of any Shares (the “Transfer Shares”) to any
person or entity, including, without limitation, any shareholder of a Participating Company, the Company shall have the right to repurchase the Transfer Shares under the terms and subject to the conditions set forth in this Section 12 (the
“Right of First Refusal”). 
 12.2 Notice of Proposed Transfer. Prior to any proposed transfer of the
• Transfer Shares, the Participant shall deliver written notice (the “Transfer Notice”) to the Company describing fully the proposed transfer, including the number of Transfer Shares, the name and address of the
proposed transferee (the “Proposed Transferee”) and, if the transfer is voluntary, the proposed transfer price, and containing such information necessary to show the bona fide nature of the proposed transfer. In the
event of a bona fide gift or involuntary transfer, the proposed transfer price shall be deemed to be the Fair Market Value of the Transfer Shares, as determined by the Board in good faith. If the Participant proposes to transfer any Transfer Shares
to more than one Proposed Transferee, the Participant shall provide a separate Transfer Notice for the proposed transfer to each Proposed Transferee. The Transfer Notice shall be signed by both the Participant and the Proposed Transferee and must
constitute a binding commitment of the Participant and the Proposed Transferee for the transfer of the Transfer Shares to the Proposed Transferee subject only to the Right of First Refusal. 

12.3 Bona Fide Transfer. If the Company determines that the information provided by the Participant in the Transfer Notice is
insufficient to establish the bona fide nature of a proposed voluntary transfer, the Company shall give the Participant written notice of the Participant’s failure to comply with the procedure described in this Section 12, and the
Participant shall have no right to transfer the Transfer Shares without first complying with the procedure described in this Section 12. The Participant shall not be permitted to transfer the Transfer Shares if the proposed transfer is not bona
fide. 
 12.4 Exercise of Right of First Refusal. If the Company determines the proposed transfer to be bona fide, the Company shall
have the right to purchase all, but not less than all, of the Transfer Shares (except as the Company and the Participant otherwise agree) at the purchase price and on the terms set forth in the Transfer Notice by delivery to the Participant of a
notice of exercise of the Right of First Refusal within thirty (30) days after the date the Transfer Notice is delivered to the Company. The Company’s exercise dr failure to exercise the Right of First Refusal with respect to any proposed
transfer described in a Transfer Notice shall not affect the Company’s right to exercise the Right of First Refusal with respect to any proposed transfer described in any other Transfer Notice, whether or not such other Transfer Notice is
issued by the Participant or issued by a person other than the Participant with respect to a proposed transfer to the same Proposed Transferee. lithe Company exercises the Right of First Refusal, the Company and the Participant shall thereupon
consummate the sale of the Transfer 

  
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Shares to the Company on the terms set forth in the Transfer Notice within sixty (60) days after the date the Transfer Notice is delivered to the Company (unless a longer period is offered
by the Proposed Transferee); provided, however, that in the event the Transfer Notice provides for the payment for the Transfer Shares other than in cash, the Company shall have the option of paying for the Transfer Shares by the present value cash
equivalent of the consideration described in the Transfer Notice as reasonably determined by the Company. For purposes of the foregoing, cancellation of any indebtedness of the Participant to any Participating Company shall be treated as payment to
the Participant in cash to the extent of the unpaid principal and any accrued interest canceled. 
 12.5 Failure to Exercise Right of
First Refusal. If the Company fails to exercise the Right of First Refusal in full (or to such lesser extent as the Company and the Participant otherwise agree) within the period specified in Section 12.4 above, the Participant may conclude
a transfer to the Proposed Transferee of the Transfer Shares on the terms and conditions described in the Transfer Notice, provided such transfer occurs not later than ninety (90) days following delivery to the Company of the Transfer Notice.
The Company shall have the right to demand further assurances from the Participant and the Proposed Transferee (in a form satisfactory to the Company) that the transfer of the Transfer Shares was actually carried out on the terms and conditions
described in the Transfer Notice. No Transfer Shares shall be transferred on the books of the Company until the Company has received such assurances, if so demanded, and has approved the proposed transfer as bona fide. Any proposed transfer on terms
and conditions different from those described in the Transfer Notice, as well as any subsequent proposed transfer by the Participant, shall again be subject to the Right of First Refusal and shall require compliance by the Participant with the
procedure described in this Section 12. 
 12.6 Transferees of Transfer Shares. All transferees of the Transfer Shares or any
interest therein, other than the Company, shall be required as a condition of such transfer to agree in writing (in a form satisfactory to the Company) that such transferee shall receive and hold such Transfer Shares or interest therein subject to
all of the terms and conditions of this Option Agreement, including this Section 12 providing for the Right of First Refusal with respect to any subsequent transfer. Any sale or transfer of any shares acquired upon exercise of the Option shall
be void unless the provisions of this Section 12 are met. 
 12.7 Transfers Not Subject to Right of First Refusal. The Right of
First Refusal shall not apply to any transfer or exchange of the Shares acquired upon exercise of the Option if such transfer or exchange is in connection with an Ownership Change Event. If the consideration received pursuant to such transfer or
exchange consists of stock of a Participating Company, such consideration shall remain subject to the Right of First Refusal unless the provisions of Section 12.9 below result in a termination of the Right of First Refusal. 

12.8 Assignment of Right of First Refusal. The Company shall have the right to assign the Right of First Refusal at any time, whether or
not there has been an attempted transfer, to one or more persons as may be selected by the Company. 

  
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 12.9 Early Termination of Right of First Refusal. The other provisions of this Option
Agreement notwithstanding, the Right of First Refusal shall terminate and be of no further force and effect upon (a) the occurrence of a Change in Control, unless the Acquiror assumes the Company’s rights and obligations under the Option
or substitutes a substantially equivalent option for the Acquiror’s stock for the Option, or (b) the existence of a public market for the class of shares subject to the Right of First Refusal. A “public market”
shall be deemed to exist if (i) such stock is listed on a national securities exchange (as that term is used in the Exchange Act) or (ii) such stock is traded on the
over-the-counter market and prices therefor are published daily on business days in a recognized financial journal. 

 

	 	13.	 STOCK DISTRIBUTIONS SUBJECT TO OPTION AGREEMENT. 

If, from time to time, there is any stock dividend, stock split or other change, as described in Section 9, in the character or amount of
any of the outstanding stock of the corporation the stock of which is subject to the provisions of this Option Agreement, then in such event any and all new, substituted or additional securities to which the Participant is entitled by reason of the
Participant’s ownership of the shares acquired upon exercise of the Option shall be immediately subject to the Right of First Refusal with the same force and effect as the shares subject to the Right of First Refusal immediately before such
event. 
  

	 	14.	 NOTICE OF SALES UPON DISQUALIFYING DISPOSITION. 

The Participant shall dispose of the shares acquired pursuant to the Option only in accordance with the provisions of this Option Agreement. In
addition, if the Grant Notice designates this Option as an Incentive Stock Option, the Participant shall (a) promptly notify the Chief Financial Officer of the Company if the Participant disposes of any of the shares acquired pursuant to
the Option within one (1) year after the date the Participant exercises all or part of the Option or within two (2) years after the Date of Grant and (b) provide the Company with a description of the circumstances of such disposition.
Until such time as the Participant disposes of such shares in a manner consistent with the provisions of this Option Agreement, unless otherwise expressly authorized by the Company, the Participant shall hold all shares acquired pursuant to the
Option in the Participant’s name (and not in the name of any nominee) for the one-year period immediately after the exercise of the Option and the two-year period
immediately after Date of Grant. At any time during the one-year or two-year periods set forth above, the Company may place a legend on any certificate representing
shares acquired pursuant to the Option requesting the transfer agent for the Company’s stock to notify the Company of any such transfers. The obligation of the Participant to notify the Company of any such transfer shall continue
notwithstanding that a legend has been placed on the certificate pursuant to the preceding sentence. 
  

	 	15.	 LEGENDS. 

The Company may at any time place legends referencing the Right of First Refusal and any applicable federal, state or foreign securities law
restrictions on all certificates representing shares of stock subject to the provisions of this Option Agreement. The Participant shall, at the request of the Company, promptly present to the Company any and all certificates representing shares
acquired pursuant to the Option in the possession of the Participant in order to carry out the provisions of this Section. Unless otherwise specified by the Company, legends placed on such certificates may include, but shall not be limited to, the
following: 

  
 11 

 15.1 “THE SECURITIES EVIDENCED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE
SECURITIES ACT OF 1933, AS AMENDED, AND MAY NOT BE SOLD, TRANSFERRED, ASSIGNED OR HYPOTHECATED UNLESS THERE IS AN EFFECTIVE REGISTRATION STATEMENT UNDER SUCH ACT COVERING SUCH SECURITIES, THE SALE IS MADE IN ACCORDANCE WITH RULE 144 OR RULE 701
UNDER THE ACT, OR THE COMPANY RECEIVES AN OPINION OF COUNSEL REASONABLY SATISFACTORY TO THE COMPANY, STATING THAT SUCH SALE, TRANSFER, ASSIGNMENT OR HYPOTHECATION IS EXEMPT FROM THE REGISTRATION AND PROSPECTUS DELIVERY REQUIREMENTS OF SUCH
ACT.” 
 15.2 “THE SHARES REPRESENTED BY THIS CERTIFICATE ARE SUBJECT TO CERTAIN RESTRICTIONS ON TRANSFER, INCLUDING A RIGHT OF
FIRST REFUSAL OPTION AND RIGHT OF REPURCHASE IN FAVOR OF THE CORPORATION OR ITS ASSIGNEE SET FORTH IN AN AGREEMENT BETWEEN THE CORPORATION AND THE REGISTERED HOLDER, OR SUCH HOLDERS PREDECESSOR IN INTEREST, A COPY OF WHICH IS ON FILE AT THE
PRINCIPAL OFFICE OF THIS CORPORATION.” 
 15.3 “THE SHARES EVIDENCED BY THIS CERTIFICATE WERE ISSUED BY THE CORPORATION TO THE
REGISTERED HOLDER UPON EXERCISE OF AN INCENTIVE STOCK OPTION AS DEFINED IN SECTION 422 OF THE INTERNAL REVENUE CODE OF 1986, AS AMENDED (“ISO”). IN ORDER TO OBTAIN THE PREFERENTIAL TAX TREATMENT AFFORDED TO ISOs, THE SHARES SHOULD NOT BE
TRANSFERRED PRIOR TO [INSERT DISQUALIFYING DISPOSITION DATE HERE]. SHOULD THE REGISTERED HOLDER ELECT TO TRANSFER ANY OF THE SHARES PRIOR TO THIS DATE AND FOREGO ISO TAX TREATMENT, THE TRANSFER AGENT FOR THE SHARES SHALL NOTIFY THE
CORPORATION IMMEDIATELY. THE REGISTERED HOLDER SHALL HOLD ALL SHARES PURCHASED UNDER THE INCENTIVE STOCK OPTION IN THE REGISTERED HOLDER’S NAME (AND NOT IN THE NAME OF ANY NOMINEE) PRIOR TO THIS DATE OR UNTIL TRANSFERRED AS DESCRIBED
ABOVE.” 
  

	 	16.	 LOCK-UP AGREEMENT. 

The Participant hereby agrees that in the event of any underwritten public offering of stock, including an initial public offering of stock,
made by the Company pursuant to an effective registration statement filed under the Securities Act, the Participant shall not offer, sell, contract to sell, pledge, hypothecate, grant any option to purchase or make any short sale of, or otherwise
dispose of any shares of stock of the Company or any rights to acquire stock of the Company for such period of time from and after the effective date of such registration statement as may be established by the underwriter for such public offering;
provided, however, that such period of time shall not exceed one hundred eighty (180) days from the effective date of the registration statement to be filed in connection with such public offering. The foregoing limitation shall not apply to
shares registered in the public offering under the Securities Act. The Participant hereby agrees to enter into any agreement reasonably required by the underwriters to implement the foregoing within a reasonable timeframe if so requested by the
Company. 

  
 12 

	 	17.	 RESTRICTIONS ON TRANSFER OF SHARES. 

No shares acquired upon exercise of the Option may be sold, exchanged, transferred (including, without limitation, any transfer to a nominee or
agent of the Participant), assigned, pledged, hypothecated or otherwise disposed of, including by operation of law in any manner which violates any of the provisions of this Option Agreement, and any such attempted disposition shall be void. The
Company shall not be required (a) to transfer on its books any shares which will have been transferred in violation of any of the provisions set forth in this Option Agreement or (b) to treat as owner of such shares or to accord the right
to vote as such owner or to pay dividends to any transferee to whom such shares will have been so transferred. 
  

	 	18.	 MISCELLANEOUS PROVISIONS. 

18.1 Further Instruments. The parties hereto agree to execute such further instruments and to take such further action as may reasonably
be necessary to carry out the intent of this Option Agreement. 
 18.2 Binding Effect. Subject to the restrictions on transfer set
forth herein, this Option Agreement shall inure to the benefit of and be binding upon the parties hereto and their respective heirs, executors, administrators, successors and assigns. 

18.3 Termination or Amendment. The Board may terminate or amend the Plan or the Option at any time; provided, however, that except as
provided in Section 8 in connection with a Change in Control, no such termination or amendment may adversely affect the Option or any unexercised portion hereof without the consent of the Participant unless such termination or amendment is
necessary to comply with any applicable law or government regulation. No amendment or addition to this Option Agreement shall be effective unless in writing. Notwithstanding any other provision of this Option Agreement to the contrary, the Board
may, in its sole and absolute discretion and without the consent of the Participant, amend this Option Agreement, to take effect retroactively or otherwise, as it deems necessary or advisable for the purpose of conforming this Option Agreement to
any present or future law, regulation or rule applicable to this Option Agreement, including, but not limited to, Section 409A of the Code and all applicable guidance promulgated thereunder. 

18.4 Delivery of Documents and Notices. Any document relating to participation in the Plan, or any notice required or permitted
hereunder shall be given in writing and shall be deemed effectively given (except to the extent that this Option Agreement provides for effectiveness only upon actual receipt of such notice) upon personal delivery electronic delivery at the e-mail address, if any, provided for the Participant by the Participating Company, or, upon deposit in the U.S. Post Office or foreign postal service, by registered or certified mail, or with a nationally recognized
overnight courier service with postage and fees prepaid, addressed to the other party at the address of such party set forth in the Grant Notice or at such other address as such party may designate in writing from time to time to the other party.

  
 13 

 (a) Description of Electronic Delivery. The Plan documents, which may include but do
not necessarily include: the Plan, the Grant Notice, this Option Agreement, and any reports of the Company provided eenerally to the Company’s shareholders, may be delivered to the Participant electronically. In addition, if permitted by the
Company, the Participant may deliver electronically the Grant Notice and Exercise Notice called for by Section 4.2 to the Company or to such third party involved in administering the Plan as the Company may designate from time to time. Such
means of electronic delivery may include but do not necessarily include the delivery of a link to a Company intranet or the intemet site of a third party involved in administering the Plan, the delivery of the document via e-mail or such other means of electronic delivery specified by the Company. 
 (b) Consent to
Electronic Delivery. The Participant acknowledges that the Participant has read Section 18.4(a) of this Option Agreement and consents to the electronic delivery of the Plan documents and, if permitted by the Company, the delivery of the
Grant Notice and Exercise Notice, as described in Section 18.4(a). The Participant acknowledges that he or she may receive from the Company a paper copy of any documents delivered electronically at no cost to the Participant by contacting the
Company by telephone or in writing. The Participant further acknowledges that the Participant will be provided with a paper copy of any documents if the attempted electronic delivery of such documents fails. Similarly, the Participant understands
that the Participant must provide the Company or any designated third party administrator with a paper copy of any documents if the attempted electronic delivery of such documents fails. The Participant may revoke his or her consent to the
electronic delivery of documents described in Section 18.4(a) or may change the electronic mail address to which such documents are to be delivered (if Participant has provided an electronic mail address) at any time by notifying the Company of
such revoked consent or revised e-mail address by telephone, postal service or electronic mail. Finally, the Participant understands that he or she is not required to consent to electronic delivery of
documents described in Section 18.4(a). 
 18.5 Integrated Agreement. The Grant Notice, this Option Agreement and the Plan,
together with any employment, service or other agreement with the Participant and a Participating Company referring to the Option, shall constitute the entire understanding and agreement of the Participant and the Participating Company Group with
respect to the subject matter contained herein or therein and supersede any prior agreements, understandings, restrictions, representations, or warranties among the Participant and the Participating Company Group with respect to such subject matter.
To the extent contemplated herein or therein, the provisions of the Grant Notice, the Option Agreement and the Plan shall survive any exercise of the Option and shall remain in full force and effect. 

18.6 Applicable Law. This Option Agreement shall be governed by the laws of the State of California as such laws are applied to
agreements between California residents entered into and to be performed entirely within the State of California. 
 18.7 Counterparts.
The Grant Notice may be executed in counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. 

  
 14 

							
	☐ Incentive Stock Option	 	        	  	Participant:	  	  

	☐ Nonstatutory Stock Option	 		  	Date:	  	  

 STOCK OPTION EXERCISE NOTICE 

Histogen Inc. 
 Attention: Chief Financial Officer 

San Diego, CA 
 Ladies and Gentlemen: 

Option. I was granted an option (the
“Option-) to purchase shares of the common stock (the “Shares”) of Histogen Inc. (the “Company”)
pursuant to the Company’s 2007 Stock Plan (the “Plan”), my Notice of Grant of Stock Option (the “Grant Notice”) and my Stock Option Agreement (the “Option Agreement”)
as follows: 
  

			
	Date of Grant:	  	  

		
	 Number of Option
 Shares:
	  	  

		
	 Exercise Price per
 Share:
	  	 $

 2. Exercise of Option. I hereby elect to exercise the Option to purchase the
following number of Shares, all of which are Vested Shares, in accordance with the Grant Notice and the Option Agreement: 
  

			
	Total Shares Purchased:	  	  

		
	Total Exercise Price (Total Shares X Price per Share)	  	 $

 3. Payments. I enclose payment in full of the total exercise price for the
Shares in the following form(s), as authorized by my Option Agreement: 
  

			
	☐ Cash:	  	  

		
	☐ Check:	  	  

		
	☐ Tender of Company Stock:	  	Contact Plan Administrator

 4. Tax Withholding. I authorize payroll withholding and otherwise will make
adequate provision for the federal, state, local and foreign tax withholding obligations of the Company, if any, in connection with the Option. If I am exercising a Nonstatutory Stock Option, I enclose payment in full of my withholding taxes,
if any, as follows: 
 (Contact Plan Administrator for amount of tax due.) 

 

			
	☐ Cash:	  	  

		
	☐ Check:	  	  

  
 15 

 5. Participant Information. 

 

	
	My address
is:                                        
                                         
                                         
                                         
             
	                                      
                                         
                                         
                                         
                                       

 My Social Security Number
is:                                        
                                         
                                         
                       
 6.
Notice of Disqualifying Disposition. If the Option is an Incentive Stock Option, I agree that I will promptly notify the Chief Financial Officer of the Company if I transfer any of the Shares within one (1) year from the date I
exercise all or part of the Option or within two (2) years of the Date of Grant. 
 7. Binding Effect. I
agree that the Shares are being acquired in accordance with and subject to the terms, provisions and conditions of the Grant Notice, the Option Agreement, including the Right of First Refusal set forth therein, and the Plan, to all of which
I hereby expressly assent. This Agreement shall inure to the benefit of and be binding upon my heirs, executors, administrators, successors and assigns. 

8. Transfer. I understand and acknowledge that the Shares have not been registered under the Securities Act of 1933, as amended
(the “Securities Act”), and that consequently the Shares must be held indefinitely unless they are subsequently registered under the Securities Act, an exemption from such registration is available, or they are sold in
accordance with Rule 144 or Rule 701 under the Securities Act. I further understand and acknowledge that the Company is under no obligation to register the Shares. I understand that the certificate or certificates evidencing the Shares will be
imprinted with legends which prohibit the transfer of the Shares unless they are registered or such registration is not required in the opinion of legal counsel satisfactory to the Company. 

I am aware that Rule 144 under the Securities Act, which permits limited public resale of securities acquired in a nonpublic offering, is not
currently available with respect to the Shares and, in any event, is available only if certain conditions are satisfied. I understand that any sale of the Shares that might be made in reliance upon Rule 144 may only be made in limited amounts in
accordance with the terms and conditions of such rule and that a copy of Rule 144 will be delivered to me upon request. 
 I understand that
I am purchasing the Shares pursuant to the terms of the Plan, the Grant Notice and my Option Agreement, copies of which I have received and carefully read and understand. 

 

	
	Very truly yours,
	
	  
 (Signature)

 Receipt of the above is hereby acknowledged. 
  

			
	HISTOGEN INC.
		
	By:	 	  

	Title:	 	  

	Dated:	 	  

  
 16EX-10.47

 Exhibit 10.47 

EXECUTIVE EMPLOYMENT AGREEMENT 

This EXECUTIVE EMPLOYMENT AGREEMENT (the “Agreement”) is entered into as of December 11, 2018 by and between
Histogen Inc., a Delaware corporation (“Employer”), and Richard W. Pascoe (“Employee”). 
 RECITALS

 WHEREAS, Employer desires to employ Employee as Chief Executive Officer of Employer on the terms and conditions hereinafter
set forth; and 
 WHEREAS, Employee desires to be employed by Employer as Chief Executive Officer on the terms and conditions
hereinafter set forth. 
 AGREEMENT 

NOW THEREFORE, in consideration of the foregoing premises and the mutual covenants and agreements set forth herein, Employee and
Employer agree as follows: 
 1. Employment Term. The term of this Agreement (the “Employment Term”)
shall commence on Employee’s actual start date (the “Effective Date”), which is anticipated to be on or before January 1, 2019, and will continue until terminated as provided in Section 7
below.  
 2. Scope of Employment. 

(a) Position and Duties. Employee agrees that as of the Effective Date he shall become an employee of Employer with the title of
“Chief Executive Officer”. Employee further agrees that during the Employment Term, he shall use his best efforts and his skills and experiences in the best interests of Employer. Employee shall report to the Board of Directors of Employer
(the “Board”) and perform the job duties and have the responsibilities and authority customarily performed and held by an employee in his position or as otherwise may be assigned or delegated to him by the Board. In addition,
Employee will be appointed to the Board and as the Chairman of the Board. Upon Employee’s cessation of service as Employer’s Chief Executive Officer, unless otherwise agreed between Employee and Employer in writing, Employee will be deemed
to have voluntarily resigned as a member of the Board, as a member of the board of any subsidiary of Employer of which Employee is then a member and as an officer of Employer or any of its subsidiaries of which Employee is an officer, effective
immediately. Except as may be mutually agreed between Employer and Employee, Employee shall be based at Employer’s headquarters in San Diego, California except for when business needs require Employee to travel. 

(b) Exclusive Efforts. During Employee’s employment by Employer, Employee shall render services to Employer exclusively, and shall
not render, directly or indirectly, any services or engage in business activities with any other person or entity, either as an employee, employer, consultant, agent, principal, partner, equityholder, corporate officer, director, or in any other
individual or representative capacity, without the prior written consent of the Board. Employee agrees to serve Employer faithfully, to execute to the best of his abilities the duties of his position, and to devote his entire business time,
attention, and efforts to the interests and business of Employer. Notwithstanding the foregoing, but subject at all times to the restrictions in Sections 4 and 5, and subject to approval of the Board, not to be unreasonably withheld,
Employee shall not be restricted from participating as an 

  
 -1- 

 
advisor, director or in similar capacities with charitable or professional organizations, so long as such participation (i) complies with Employer’s written employment policies, and
(ii) does not materially interfere with the satisfaction of Employee’s obligations hereunder . While employed by Employer, Employee shall not, without the prior written consent of the Board, directly or indirectly, whether as a partner,
employee, creditor, shareholder, or otherwise, promote, participate or engage in any activity or other business competitive with Employer’s business. Notwithstanding the foregoing provisions of this Section 3(b),
Employee may (A) make passive investments of not more than one percent (1%) of the outstanding shares of, or any other equity interest in, a company listed on a national securities exchange or in an over-the-counter securities market and Employee is not otherwise associated directly or indirectly with such company or with any affiliate of such company and (B) serve on the boards of directors of the
companies and organizations set forth on Schedule 1 hereto, and such investments or service shall not constitute a breach of this Section 2(b). 

(c) Compliance with Laws and Policies. Employee agrees at all times to strictly adhere to all applicable laws, rules and regulations and
with the written policies and procedures of Employer in effect from time to time and provided to Employee (to the extent such written policies and procedures are not inconsistent with the terms of this Agreement). 

(d) Representations and Covenants by Employee. Employee hereby represents and warrants that: (i) Employee’s execution,
delivery and performance of this Agreement does not and will not conflict with, breach, violate or cause a default under any contract, agreement, instrument, order, judgment or decree to which Employee is a party or by which Employee is bound,
(ii) Employee is not a party to or bound by any agreement or understanding of any type, whether written or oral, or by any statutory or common law duty or obligation which, in any case, would in any way restrict his ability to be employed by
Employer or any affiliate thereof, or Employee’s ability to compete freely with any other person, (iii) Employee is not subject to or in breach of any nondisclosure agreement, including any agreement concerning trade secrets or
confidential information owned by any other party, and (iv) Employee has the legal capacity to execute this Agreement. There is no action or proceeding pending or, to Employee’s actual knowledge, threatened against Employee that would
prevent, hinder or materially delay the performance by Employee of any of his obligations hereunder. Employee further acknowledges that Employer has a legitimate business interest in protecting the business, acquired goodwill, Trade Secrets, Records
and other Confidential Information, each capitalized term as defined on Exhibit A hereto. Employee also acknowledges and recognizes the highly competitive nature of the business of Employer. 

3. Compensation and Benefits. 

(a) Base Salary. Employer shall pay to Employee an annual base salary of ($450,000) (the “Base Salary”), minus taxes
and applicable withholdings, payable in accordance with Employer’s regularly scheduled payroll policies. Base Salary will be subject to review and adjustment (but not decrease) in accordance with Employer’s normal performance review
practices, but no less frequently than annually. Effective as of the date of any change to Employee’s Base Salary, the Base Salary as so changed shall be considered the new Base Salary for all purposes of this Agreement. 

(b) Cash Incentive Bonus. Employee is eligible to receive an annual discretionary bonus (“Cash Bonus”), paid after the
close of the applicable performance period based upon performance metrics jointly established by the Board (or any applicable committee thereof) and Employee. The target amount of Employee’s Cash Bonus will be 50% of the Base Salary (the
“Target Cash Bonus”). The Cash Bonus, if any, shall be paid to Employee in Employer’s fiscal year following the fiscal year for which it is earned. Except as set forth in Section 8(c) or
(d) of this Agreement, Employee shall not be entitled to receive the Cash Bonus if he is not employed at the time that such bonus is paid. 

  
 -2- 

 (c) Equity Awards. 

(i) New Hire Option Award. As soon as reasonably practicable following the Effective Date, Employee shall be granted a stock option to
purchase shares of Employer’s common stock representing five percent (5%) of Employer’s Fully Diluted Capitalization (the “New Hire Option Award”) as of the Effective Date. Sixty percent (60%) of the New Hire Option Award
will vest as to one-fourth (1/4th) of such shares one (1) year after the Effective Date, and as to one forty-eighth (1/48th) of such shares monthly thereafter, and the remaining forty percent (40%) of the
New Hire Option Award will vest upon the earliest to occur of (A) the closing of an underwritten initial public offering by Employer of its securities that is registered under the Securities Act of 1933, as amended, or (B) forty-five
(45) days following a Change in Control (as defined below), in each case, subject to Employee continuing to provide services to Employer through the relevant vesting dates. 

(ii) Anti-Dilution Protection. On the one (1)-year anniversary date of the Effective Date (the
“One-Year Anniversary Date”) and subject to Employee’s continued employment or service through such date, Employee shall be entitled to receive an additional grant of a stock option to
purchase shares of Employer’s common stock (the “Additional Option Award” and together with the New Hire Option Award, the “Option Awards”) in an amount of shares of Employer’s common stock as is required
such that Employee’s Option Awards, in the aggregate, represent five percent (5%) of Employer’s Fully Diluted Capitalization as of the One-Year Anniversary Date. The Additional Option Award shall be
subject to the same vesting schedule described in subclause (i) above as if such Additional Option Award was granted at the same time as the New Hire Option Award. 

(iii) Terms of Option Awards. The exercise price per share of the Option Awards will be equal to the fair market value per share on the
date the Option Awards are granted. The term of the Option Awards shall be ten (10) years, subject to earlier expiration as provided in Employer’s equity incentive or stock option plan (the “Plan”) or the Option Agreement,
as defined below. The Option Awards shall be in all respects subject to the Plan and any amendments thereto, and conditioned upon Employee’s execution of stock option agreements evidencing the grant of the Option Awards (the “Option
Agreements”). The terms and conditions upon which the Option Awards may be exercised, including, if at all, after termination of Employee’s employment or service, are governed by the Plan and the Option Agreements. 

(iv) Future Awards. Employee will continue to be eligible to receive such other long-term incentive awards as determined by the Board
in its sole discretion. 
 For purposes of this Agreement, “Fully Diluted Capitalization” includes all outstanding shares of Employer’s
capital stock, on a fully-diluted basis, determined under the treasury stock method. For purposes of Section 3(c)(ii), Fully Diluted Capitalization will be determined by the Board in its sole discretion. 

(d) Paid Time Off and Benefits. During the Employment Term, Employee shall receive personal time off (“PTO”) benefits
consistent with such benefits currently offered to Employer’s executives and any Employer’s policies as in effect from time to time. In addition, during the Employment Term, Employee shall be eligible to participate in the employee benefit
plans 

  
 -3- 

 
maintained by Employer and generally available to similarly situated employees of Employer, subject in each case to the generally applicable terms and conditions of the plan in question and to
the determinations of any person or committee administering such employee benefit plan. Employer reserves the right to cancel or change the employee benefit plans and programs it offers to its employees at any time. 

(e) Expense Reimbursement. Employer shall reimburse Employee for reasonable and necessary actual out-of-pocket business expenses incurred by Employee in connection with the performance of his duties hereunder; provided, that (i) such expenses were incurred in accordance with Employer’s
policies, including any required pre-approvals thereunder, and (ii) Employee timely provides proper documentation and receipts prior to being entitled to any reimbursement for such amounts. 

4. Trade Secrets, Confidential Information. 

(a) Employee acknowledges that, during his employment with Employer he will acquire Trade Secrets and other Confidential Information (as
defined in Exhibit A attached hereto), including information relating to the business of Employer, business methods, customers and suppliers. Employer considers the identity of customers and suppliers of Employer’s business, the contact
person for those customers and suppliers, and any other information related to business conducted between such persons and Employer to be Trade Secrets and, as such, the confidential, sole and exclusive property of Employer. 

(b) Employee understands that all Records (as defined in Exhibit A hereto) also constitute Confidential Information (and may constitute
Trade Secrets) of Employer, and that his obligations continue at all times during and after his employment. These Records do not become any less confidential or proprietary to Employer because Employee may commit some of them to memory or because he
may otherwise maintain them outside of Employer’s offices. 
 (c) Employee shall not, at any time during the term of his employment or
after the termination of his employment, disclose to others, either directly or indirectly, or take or use for Employee’s own purposes or the purposes of others, either directly or indirectly, any Trade Secret or any Confidential Information of
Employer. Employee understands and acknowledges that this obligation applies not only to technical information and customer information, but also to any business information that Employer treats as confidential. Employee agrees that all Confidential
Information of Employer is to be used by him solely and exclusively for the purpose of conducting business on behalf of Employer or its affiliated companies. If Employee resigns or is terminated from his employment for any reason, he agrees to
immediately return all Confidential Information, including Confidential Information maintained by him in his office, personal electronic devices, and/or at home. 

(d) Employee agrees to keep the terms of this Agreement confidential and shall not disclose any terms herein except to Employee’s spouse,
if applicable, attorneys or tax preparer or other professional advisors to whom such disclosure is necessary to effectuate the purposes for which Employee has consulted such professional advisors, or as required by law. Employee shall inform all
future employers that Employee is bound by this confidentiality provision. 

  
 -4- 

 (e) Notwithstanding anything to the contrary contained herein, this Agreement does not
prohibit Employee from exercising his legal rights under applicable law, including but not limited to reporting what he reasonably and in good faith believes are possible violations of applicable law or regulation to any governmental agency or
self-regulatory organization (such as but not limited to the Department of Justice, the Securities and Exchange Commission, the National Labor Relations Board, the Congress, and any agency Inspector General, or any other similar state agency), or
making other disclosures that are protected under the whistleblower provisions of applicable law or regulation. Employee does not need Employer’s prior authorization to make any such report or disclosure, nor is Employee required to notify
Employer that Employee has made any such report or disclosure. Furthermore, nothing herein is intended to prohibit Employee from cooperating in an investigation conducted by such a governmental agency or to otherwise limit his right, if any, to
receive an award for information provided to any governmental agency or entity. Notwithstanding anything to the contrary contained herein, Employee will not be held criminally or civilly liable under any federal or state trade secret law for any
disclosure of a trade secret that is made: (i) in confidence to a federal, state, or local government official, either directly or indirectly; and (ii) solely for the purpose of reporting or investigating a suspected violation of law; or
is made in a complaint or other document that is filed under seal in a lawsuit or other proceeding. If Employee files a lawsuit for retaliation by Employer for reporting a suspected violation of law, Employee may disclose Employer’s trade
secrets to Employee’s attorney and use the trade secret information in the court proceeding if Employee: (x) files any document containing the trade secret under seal; and (y) does not disclose the trade secret, except pursuant to
court order. 
 5. Nonsolicitation; Non-Disparagement. 

(a) Nonsolicitation. To the fullest extent permitted under applicable law, during the period commencing on the date of this
Agreement and continuing until the first anniversary of the date when Employee’s employment is terminated for any reason, Employee shall not directly or indirectly, personally or through others, solicit, recruit or attempt to solicit or recruit
(on Employee’s own behalf or on behalf of any other person or entity) either (a) any employee or any consultant of Employer or any of Employer’s affiliates or (b) the business of any customer of Employer or any of Employer’s
affiliates on whom Employee called or with whom Employee became acquainted during his employment, if Employee is using confidential or proprietary information of Employer to effectuate the solicitation of any such customer. Employee represents that
he (i) is familiar with the foregoing covenant not to solicit, and (ii) is fully aware of his obligations hereunder, including, without limitation, the reasonableness of the length of time, scope and geographic coverage of these covenants.

 (b) Non-Disparagement. For the consideration herein provided, Employee agrees not to
disparage or defame in any manner, whether directly or indirectly, Employer, its affiliates, officers, directors, employees, products or services following termination of employment. 

(c) Survival. Employee hereby acknowledges and agrees that given the knowledge he will acquire during his employment with Employer,
including knowledge regarding the strategy, products, customers and goodwill of the business and assets of Employer, it is of paramount importance to Employer that this Agreement contains enforceable restrictive covenants, such that Employer is
willing to provide Employee with the compensation and benefits described in this Agreement for his adherence to such covenants following the termination of his employment, regardless of the reason for his termination. Accordingly, Employee agrees
that Sections 4, 5 and 6 shall survive the termination of this Agreement. 

  
 -5- 

 6. Remedies Upon Breach. Employee hereby acknowledges and agrees that the services to
be rendered by him to Employer are of a special and unique character, which gives this Agreement a peculiar value to Employer. Employee further acknowledges and agrees that a breach or threatened breach by him of any of the provisions contained in
Section 4 or Section 5 will cause irreparable injury to Employer. Employee therefore agrees that, in addition to any other right or remedy Employer may have, Employer shall be entitled to a
temporary restraining order and to a preliminary and permanent injunction enjoining or restraining the breach or threatened breach of Section 4 or Section 5 by Employee, without the necessity of
proving the inadequacy of monetary damages or the posting of any bond or security. Employee further agrees that Employer shall have the right to have the provisions of Section 4 and Section 5
specifically enforced and to require Employee to account for and pay over to Employer all compensation, profits, moneys, accruals, increments or other benefits derived or received by Employee as the result of any transactions constituting a breach
of such provisions. 
 7. Termination. 

(a) Employment at Will. Employee’s employment shall be “at will,” meaning that either Employee or Employer shall be
entitled to terminate Employee’s employment at any time and for any reason, with or without Cause or notice. This Agreement shall constitute the full and complete agreement between Employee and Employer on the
“at-will” nature of Employee’s employment, which may only be changed in an express written agreement signed by Employee and an authorized officer of Employer. 

(b) Rights Upon Termination. Except as expressly provided in Section 8, upon the termination of
Employee’s employment with Employer, Employee shall only be entitled to the accrued but unpaid Base Salary due to him through the date of termination, any earned but unused PTO through the date of termination in accordance with Employer’s
PTO policy, any vested benefits under Employer’s welfare and pension benefit plans (other than any severance plans) pursuant to the terms of such plans, and any unreimbursed business expenses incurred by Employee in accordance with this
Agreement and Employer’s expense policies. 
 8. Payments and Obligations Upon Termination 

(a) Termination for Cause, Voluntary Termination, Death or Disability. If this Agreement terminates prior to the end of the Employment
Term due to Employer’s termination of Employee for Cause, Employee’s resignation other than for Good Reason (as defined below), Employee’s death or Employee’s Disability, then except as provided in
Section 7(b), Employee agrees that he shall not be eligible for any additional compensation or benefits. 
 (b)
Termination without Cause On or Prior to One-Year Anniversary Date. If, prior to and including the One-Year Anniversary Date (x) Employer terminates Employee
for a reason other than Cause, death or Disability or Employee resigns for Good Reason, , then, subject to Section 8(f), Employee shall be entitled to the payments set forth in Section 7(b)
and continuing compensation equal to one month of Base Salary for each full month of his employment through the termination date, payable in accordance with Employer’s then-current payroll policies and practices (the “Partial Year
Compensation Continuation”), and additionally such portion of the then-unvested New Hire Option Award shall immediately vest effective as of the termination date as would have vested through the termination date had such New Hire Option
Award been scheduled to vest in forty-eight (48) equal monthly installments following the Effective Date. 

  
 -6- 

 (c) Termination without Cause After One-Year
Anniversary Date. If, after the One-Year Anniversary Date (x) Employer terminates Employee for a reason other than Cause, death or Disability or Employee resigns for Good Reason, then, subject
to Section 8(f), Employee shall be entitled to the payments set forth in Section 7(b) and the following from Employer: 

(i) continuing compensation equal to twelve (12) months of the Base Salary, payable in accordance with Employer’s then-current
payroll policies and practices (together with the Partial Year Compensation Continuation, the “Compensation Continuation”); 

(ii) the Cash Bonus (if any) accrued, and unpaid, as of the date of termination for the calendar year prior to the calendar year in which the
termination occurs, payable when bonuses are otherwise payable by the Company; 
 (iii) the pro rata portion (as determined based on the
number of days that Employee was employed during a calendar year divided by 365) of Employee’s Target Cash Bonus for the calendar year in which the termination occurs (the “Pro Rata Bonus”), payable on the Payment Date (as
defined below); and 
 (iv) such portion of the then-unvested New Hire Option Award as would have vested during the twelve (12) month
period following the date of termination had Employee remained in continuous service with Employer during such period shall vest effective as of the termination date. 

(d) Termination without Cause or Resignation for Good Reason in Connection with a Change in Control. If, during the Change in Control
Period, (x) Employer (or any parent or successor of Employer) terminates Employee’s employment for a reason other than Cause, death or Disability or Employee resigns for Good Reason, as defined below, then, subject to
Section 8(f), Employee shall be entitled to the benefits as provided in Section 8(c) and (i) additionally 100% of the then-unvested Option Awards shall immediately vest and (ii) instead
of compensation described in Section 8(c)(iii), Employee’s Target Cash Bonus for the calendar year in which the termination occurs, payable on the Payment Date (as defined below). 

(e) Definitions. For purposes of this Section 8, the following definitions apply: 

(i) “Cause” means the occurrence of any of the following, as determined in the Board’s sole discretion:
(A) Employee’s failure to materially perform his duties to the standards required by Employer or repeated neglect of Employee’s duties under this Agreement (other than by reason of physical or mental illness or disability that does
not constitute a Disability), which failure remains uncured (if capable of cure as determined by the Board) for ten (10) business days following written notice thereof by Employer to Employee; provided, however, that, if such
failure is not reasonably capable of cure without material cost or liability to Employer, then this provision will be triggered immediately upon such failure; (B) Employee’s willful misconduct, material breach of any of Employer’s
written employment policies or gross insubordination, which act remains uncured (if capable of cure as determined by the Board) for ten (10) business days following written notice thereof by Employer to Employee; provided,
however, that, if such failure is not reasonably capable of cure without material cost or liability to Employer, then this provision will be triggered immediately upon such failure; (C) Employee’s engagement in any illegal act,
substance abuse or any other misconduct that has a material adverse effect on Employer’s reputation or business operations, assets, properties, results of operations or financial condition, as reasonably determined by the Board;
(D) Employee’s (i) commission of an act involving dishonesty in the execution of Employee’s duties, fraud, embezzlement or theft; (ii) (x) indictment for, or plea of guilty or nolo contendere to, any crime

  
 -7- 

 
constituting a felony or (y) conviction of, or plea of guilty or nolo contendere to, any crime (non-felony) involving moral turpitude; or
(iii) engaging in any activity that constitutes sexual harassment or misconduct, discrimination or other workplace misconduct or a material violation of any written Employer policy applicable thereto; or (E) Employee’s material breach
of this Agreement (which breach is not otherwise covered by the definition of Cause), which breach remains uncured (if capable of cure as determined by the Board) for ten (10) business days following written notice thereof by Employer to
Employee; provided, however, that that, if such failure is not reasonably capable of cure without material cost or liability to Employer, then this provision will be triggered immediately upon such failure. 

(ii) “Change in Control” means (A) the sale, lease exchange license or other disposition of all or substantially all of
Employer’s assets in one transaction or a series of related transactions, (B) a merger or consolidation as a result of which the holders of Employer’s issued and outstanding voting securities immediately before such transaction own or
control less than a majority of the voting securities of the continuing or surviving entity immediately after such transaction and/or (C) the acquisition (in one or more transactions) by any person or persons acting together or constituting a
“group” under Section 13(d) of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), together with any affiliates thereof (other than members of Employer as of the date hereof and their respective
affiliates) of beneficial ownership (as defined in Rule 13d-3 under such Exchange Act) or control, directly or indirectly, of at least fifty percent (50%) of the total voting power of all classes of securities
entitled to vote generally in the election of the Board or similar governing body; provided, that for the purposes of the immediately preceding clause (C) neither a public offering of Employer’s securities nor any financing
transaction or series of financing transactions, whether involving existing or new investors or both, shall constitute a Change in Control. 

(iii) “Change in Control Period” means the period that commences upon a Change in Control and ends on the one (1) year
anniversary following a Change in Control. 
 (iv) “Disability” shall mean if Employee is unable to perform the essential
functions of Employee’s position, with or without reasonable accommodation, due to legal, physical or mental incapacity for a period beyond any leave to which Employee is entitled under applicable law or Employer’s policies. Any leaves of
absence shall be unpaid unless otherwise required by applicable law. It is acknowledged and agreed that termination pursuant to this provision as defined herein shall not give rise to any right other than as expressly set forth herein. 

(v) “Good Reason” means the occurrence of any of the following without Employee’s consent: (A) a material
diminution in Employee’s duties and responsibilities or a material negative change in Employee’s reporting relationship (including any requirement that Employee stops reporting to the Board), including, without limitation, following an
IPO, the Employee ceasing to be the Chief Executive Officer of a publicly-traded company following the occurrence of a Change in Control, (B) a material reduction of Employee’s base compensation (other than in connection with a general
decrease in base salaries for the officers of Employer or successor corporation), (C) a requirement that Employee perform his services at a facility or location more than fifty (50) miles from Employer’s location as of the Effective Date,
or (D) Employer’s material breach of this Agreement. No event or condition will constitute Good Reason unless and until Employee has provided Employer with written notice of the event or condition no later than sixty (60) days after
the first occurrence and Employer has failed to fully remedy such event or condition within thirty (30) days of receiving such notice, and Employee must have terminated Employee’s employment with Employer within thirty (30) days after
the expiration of the thirty (30)-day remedial period. 

  
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 (vi) A “termination of employment” shall mean the date that Employee
permanently ceases performing services for Employer as an employee even though Employee may remain on Employer’s books and records as an employee so that Employer may fulfill its obligations under this Section 8. 

(f) Conditions to Receipt of Severance. Notwithstanding any other provision of this Agreement, the receipt of any termination benefits
(not otherwise required to be provided to Employer under applicable law) pursuant to this Section 8 will be subject to Employee signing and not revoking a separation agreement and release of claims with Employer in
substantially the form attached hereto as Exhibit C (the “Release”) and provided that such Release becomes effective and irrevocable no later than sixty (60) days following Employee’s “separation of
service” within the meaning of Section 409A of the Internal Revenue Code of 1986, as amended and restated (the “Code” and such Code section, “Section 409A”) (the “Release
Deadline”). The termination benefits shall be paid or provided or shall commence on the first payroll period following the date the Release becomes effective (the “Payment Date”) and the first payment shall include all
accrued amounts from the date of termination, provided that if the period during which you may deliver the Release required hereunder spans two (2) calendar years, the Payment Date shall be no earlier than January 1 of the second calendar
year, provided that if the period during which the Release Deadline may occur spans two calendar years, the Payment Date will be no earlier than January 1 of the second calendar year. If the Release does not become effective and
irrevocable by the Release Deadline, Employee will forfeit any rights to termination benefits under this Agreement. In no event will termination benefits be paid or provided until and unless the Release becomes effective and irrevocable by the
Release Deadline. In addition, in the event that Employee materially breaches (and fails to cure, within ten (10) business days of receipt of written notice from Employer of such material breach, if such breach is capable of cure) the
provisions of Sections 4 and 5, all Compensation Continuation and benefits to which he may otherwise be entitled pursuant to this Section 8 will immediately cease. 

9. Ownership of Work Product and Inventions. 

(a) Ownership. Employer shall own all rights to “Work Product” (as defined below) created by Employee. Employee hereby assigns
to Employer all copyright, trademark, trade secrecy, and patent rights in the Work Product. Employee will take all action reasonably requested by Employer to transfer rights to the Work Product to Employer and to permit Employer to obtain copyright,
trademark, patent, or similar protection for the Work Product in its own name in any jurisdiction. Employee hereby waives in whole any moral rights which he may have in any such Work Product or any part or parts thereof. If Employee makes any
“Invention” (as defined below) during the Employment Term that Employee believes does not belong to Employer under this Agreement, then Employee will promptly notify the Board and will supply a written explanation of the reasons for such
belief. Employee is not the owner of any invention as of the date hereof. Employee agrees that even if his employment is terminated by Employer, Employee shall at all times provide reasonable cooperation with Employer in the prosecution or defense
of any lawsuit related to Employer activities in connection with any copyright of Employer.  
 (b) Definitions. For purposes
of this Agreement, the following terms shall have the following meanings: 
 (i) “Work Product” means written materials
created by Employee, Inventions made by Employee, programs, fixes, routines, inventions, ideas, designs, manuals, improvements, discoveries, processes, and any other results or properties of Employee’s efforts whether produced alone or with
others, a) relating to Employer’s actual or anticipated business, or b) made or conceived during working hours or developed with the aid of Employer’s personnel or assets. 

  
 -9- 

 (ii) “Invention” means any invention, including, without limitation,
information, inventions, contributions, improvements, ideas, or discoveries, whether patentable or copyrightable or not, and whether or not conceived or made during work hours. 

(c) Limitations. All provisions of this Agreement relating to the assignment by Employee of any invention or innovation are subject to
the provisions of California Labor Code Sections 2870, 2871 and 2872. Employee understands that, in accordance with Section 2870 of the California Labor Code, the provisions of this Agreement requiring assignment to Employer, without
payment, of any rights in any Inventions would not apply to any invention for which no equipment, supplies, facility, or trade secret information of Employer was used and which was developed entirely on Employee’s own time, unless (i) the
invention relates (A) directly to the business of Employer, or (B) to Employer’s actual or demonstrably anticipated research or development, or (ii) the invention results from any work performed by Employee for Employer. A copy
of California Labor Code Sections 2870, 2871 and 2872 is attached to this Agreement as Exhibit B. 
 10.
Compliance with Internal Revenue Code Section 409A. In the event that any compensation or other payments payable under this Agreement are subject to Section 409A, then Employee acknowledges and agrees that Employer
shall adhere to the provisions of Section 409A and any regulations or other guidance issued thereunder. Employee agrees that he has reviewed or been advised to review (and had ample opportunity to review) the provisions of this Agreement with
applicable legal and tax counsel to ensure compliance with Section 409A and that Employer shall not be responsible for any adverse tax consequences experienced by Employee in connection with this Agreement. Employee’s right to receive any
installment payments pursuant to this Agreement will be treated as a right to receive a series of separate payments. For purposes of this Agreement, references to “termination of employment” (and substantially similar phrases) will be
interpreted to mean a “separation from service” within the meaning of Section 409A. If, as of the date of Employee’s “separation from service” from Employer, Employee is a “specified employee” (within the
meaning of Section 409A), then: (a) each installment of the Compensation Continuation that, in accordance with the dates and terms set forth in this Agreement, will in all circumstances, regardless of when the “separation from
service” occurs, be paid within the short-term deferral period (as defined in Section 409A) will be treated as a “short-term deferral” within the meaning of Treas. Reg.
Section 1.409A-l(b)(4) to the maximum extent permissible under Section 409A and will be paid on the dates and terms set forth in this Agreement; and (b) each installment of the Compensation
Continuation that is not described in clause (a) above and that would, absent this clause (b), be paid within the six-month period following Employee’s “separation from service” from
Employer will not be paid until the date that is six months and one day after such “separation from service” (or, if earlier, Employee’s death), with any such installments that are required to be delayed being accumulated during the six-month period and paid in a lump sum on the date that is six months and one day following Employee’s “separation from service” and any subsequent installments, if any, being paid in accordance with
the dates and terms set forth in this Agreement; provided, however, that the preceding provisions of this clause (b) will not apply to any installment of the Compensation Continuation if and to the maximum extent that that such
installment is deemed to be paid under a separation pay plan that does not provide for a deferral of compensation by reason of the application of Treas. Reg. Section 1.409A-l(b)(9)(iii) (relating to
separation pay upon an involuntary separation from service). Any installments that qualify for the exception under Treas. Reg. Section 1.409A-l(b)(9)(iii) must be paid no later than the last day of
Employee’s second taxable year following the taxable year in which the “separation from service” 

  
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occurs. The determination of whether and when Employee’s “separation from service” from Employer has occurred will be made in a manner consistent with, and based on the
presumptions set forth in, Treas. Reg. Section l.409A-1(h). Solely for purposes of this paragraph, “Employer” will include all persons with whom Employer would be considered a single employer under
Section 414(b) and 414(c) of the Code. All reimbursements and in-kind benefits provided under this Agreement will be made or provided in accordance with the requirements of Section 409A to the extent
that such reimbursements or in-kind benefits are subject to Section 409A, including, where applicable, the requirements that (i) any reimbursement is for expenses incurred during Employee’s
lifetime (or during a shorter period of time specified in this Agreement), (ii) the amount of expenses eligible for reimbursement during a calendar year may not affect the expenses eligible for reimbursement in any other calendar year,
(iii) the reimbursement of any eligible expense will be made on or before the last day of the calendar year following the year in which the expense is incurred, and (iv) the right to reimbursement is not subject to set off or liquidation
or exchange for any other benefit. 
 11. Section 280G. Notwithstanding anything to the contrary contained in this Agreement, to the
extent that any of the payments and benefits provided for under this Agreement or any other agreement or arrangement between Employer and Employee (collectively, the “Payments”) (a) constitute a “parachute payment” within
the meaning of Section 280G of the Code (“Section 280G”) and (b) but for this Section 11, would be subject to the excise tax imposed by Section 4999 of the Code
(“Section 4999”), then (i) if immediately prior to transaction that constitutes a “Change in Control” of Employer under Treas. Reg. Section 1.280G which resulted in the Payments, the stock of
Employer is not publicly traded and the exemption described in Section 280G(b)(5) of the Code would apply to payments by Employer to the Employee in connection with a Change in Control (as defined in Section 280G and the regulations
promulgated thereunder), Employer and Employee shall cooperate in good faith in connection with Employer satisfying the shareholder approval exemption under Section 280G(b)(5) of the Code and the regulations thereunder, and (ii) if clause
(i) does not apply, the Payments will be reduced to the extent necessary so that no portion of such Payments retained by Employee will be subject to excise tax under Section 4999; provided, however, such reduction will only
occur if after taking into account the applicable federal, state and local income taxes and the excise tax imposed by Section 4999, such reduction results in Employee’s receipt on an after-tax basis,
of the greatest amount of benefits under this Agreement, notwithstanding that all or some portion of such benefits may be taxable under Section 4999 of the Code. To the extent permitted by applicable law, and not a violation of Sections 280G,
409A or 4999 of the Code, Employee will be entitled to elect the order in which payments will be reduced. If Employee electing the order in which payments will be reduced would result in violation of Section 409A or loss of the benefit of
reduction under Sections 280G or 4999, payments will be reduced in the following order (1) severance payment based on multiple of Base Salary and/or Cash Bonus; (2) other cash payments; (3) any
pro-rated Cash Bonus paid as severance; (4) acceleration of vesting of stock options with an exercise price that exceeds the then fair market value of stock subject to the option, provided such options
are not permitted to be valued under Treas. Reg. Section 1.280G-1 Q/A – 24(c); (5) any equity awards accelerated or otherwise valued at full value, provided such equity awards are not permitted to be
valued under Treas, Reg. Section 1.280G-1 Q/A – 24(c); (6) acceleration of vesting of stock options with an exercise price that exceeds the then fair market value of stock subject to the option,
provided such options are permitted to be valued under Treas. Reg. Section 1.280G-1 Q/A – 24(c); (7) acceleration of vesting of all other stock options and equity awards; and (8) within any
category, reductions will be from the last due payment to the first. All determinations regarding the application of this Section 11 shall be made by an accounting firm or consulting group with nationally recognized
standing and substantial expertise and experience in performing calculations regarding the applicability of Section 280G of the Code retained by Employer prior to the date of the applicable change in control and reasonably acceptable

  
 -11- 

 
to Employee (the “280G Firm”). The 280G Firm will be directed to submit its determination and detailed supporting calculations to both Employee and Employer within thirty
(30) days after notification from either Employer or Employee that Employee may receive Payments which may be “parachute payments” within the meaning of Section 280G (or such earlier or later date as Employer and Employee may
agree). Employee and Employer will each provide the 280G Firm access to and copies of any books, records, and documents in their possession as may be reasonably requested by the 280G Firm, and otherwise cooperate with the 280G Firm in connection
with the preparation and issuance of the determinations and calculations contemplated by this letter agreement. The fees and expenses of the 280G Firm for its services in connection with the determinations and calculations contemplated by this
Section 11 will be borne by Employer. The costs of obtaining such determination and all related fees and expenses (including related fees and expenses incurred in any later audit) shall be borne by Employer. 

12. Notices. All notices, requests, demands, claims, consents and other communications that are required or otherwise delivered
hereunder shall be in writing and shall be deemed to have been duly given if (a) personally delivered, (b) sent by nationally recognized overnight courier, (c) mailed by registered or certified mail with postage prepaid, return
receipt requested, or (d) transmitted by email, to the parties hereto at the following addresses (or at such other address for a party as shall be specified by like notice): 

if to Employer, to: 

Histogen Inc. 

10655 Sorrento Valley Road 

San Diego, California 92121 

Attention: HR Department 

Email:
                                     

With a copy to (which will not constitute notice): 

Sheppard, Mullin, Richter & Hampton LLP 

333 South Hope Street, 48th Floor 

Los Angeles, California 90071 

Attention: Will Chuchawat 

Email: wchuchawat@sheppardmullin.com 

if to Employee, to such address as set forth in Employer’s records, 

or to such other address as the party to whom such notice or other communication is to be given may have furnished to each other party in writing in
accordance herewith. Any such notice or communication shall be deemed to have been received (i) when delivered, if personally delivered, (ii) when sent, if sent by e-mail during normal business hours
on a business day (or, if not sent during normal business hours on a business day, on the next business day after the date sent by facsimile), (iii) on the next business day after dispatch, if sent by nationally recognized, overnight courier
guaranteeing next business day delivery, and (iv) on the fifth business day following the date on which the piece of mail containing such communication is posted, if sent by mail. 

13. Governing Law. This Agreement shall be governed by and construed in accordance with the domestic laws of the State of California
without giving effect to any choice of law or conflict of law provision or rule (whether of the State of California or any other jurisdiction) that would cause the application of the laws of any jurisdiction other than the State of California. 

  
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 14. Arbitration. 

(a) Agreement to Arbitrate. Employee and Employer agree that any and all disputes, claims or controversies whatsoever between them (and
their affiliates, if any) arising out of or related to (i) Employee’s employment with Employer, or the termination thereof, (ii) Employee’s performance of services for Employer, or (iii) this Agreement, will be settled by
final and binding arbitration in accordance with the rules and procedures of the Judicial Arbitration and Mediation Services, Inc. (“JAMS”) applicable to the dispute. JAMS rules for Employment Arbitration are available at
http://www.jamsadr.com/rules-employment-arbitration/. 
 (b) Claims Subject to Arbitration. Claims subject to arbitration shall
include, but are not limited to, claims concerning the Employee’s employment with Employer, Employee’s performance of services for Employer, and this Agreement, including claims based on any federal, state, or local law, statute, or
regulation, including, but not limited to, any claims of discrimination, harassment, retaliation or other conduct in violation of or arising under Title VII of the Civil Rights Act of 1964 (as amended by the Civil Rights Act of 1991), the Age
Discrimination in Employment Act, the Older Workers Benefit Protection Act, the Americans with Disabilities Act, the Family and Medical Leave Act, the California Fair Employment and Housing Act, and the California Family Rights Act, claims for
unpaid wages, commissions, bonuses, stock options or other employment compensation, claims for breach of contract or breach of implied covenant (express or implied), claims of wrongful termination in violation of contract or public policy,
promissory estoppel, claims arising under common law, and tort claims. 
 (c) Claims Not Subject to Arbitration. This arbitration
provision does not apply to or cover the following claims: (i) claims by Employee for workers’ compensation benefits; (ii) claims by Employee for unemployment compensation benefits; and (iii) any claim that may not be compelled
to arbitration as a matter of law. Further, either Employee or Employer, in a court of competent jurisdiction, may seek to compel arbitration under this Agreement, to enforce an arbitration award or to obtain preliminary injunctive and/or other
equitable relief in support of claims to be prosecuted in an arbitration to the extent allowed by California Code of Civil Procedure Section 1281.8. 

(d) Arbitration Procedures. The arbitration shall take place in San Diego County, California. The arbitration will be conducted
before an arbitrator who is a member of JAMS and mutually selected by the parties from the JAMS Panel. In the event that the parties are unable to mutually agree upon an arbitrator, selection of an arbitrator shall be governed by the applicable
JAMS rules. The arbitrator shall have the authority to grant all monetary or equitable relief (including, without limitation, injunctive relief, ancillary costs and fees and punitive damages) available under state and federal law. Either
party shall have the right to appeal any adverse rulings or judgments to the JAMS Panel of Retired Appellate Court Justices. The arbitrator may grant any remedy or relief to which the parties would have otherwise been entitled had the matter
been heard in a court of law, and shall not grant any remedy or relief that could not have been granted had the matter been heard in a court of law. The parties agree that the arbitrator shall not have the power to commit errors of law or legal
reasoning, and that the award may be vacated or corrected on appeal to a California state court of competent jurisdiction for any such error. Judgment on any award rendered by the arbitrator may be entered and enforced by any court having
jurisdiction thereof. 

  
 -13- 

 To the extent permitted by law, the hearing and all filings and other proceedings shall be treated in a
private and confidential manner by the arbitrator and all parties and representatives, and shall not be disclosed except as necessary for any related judicial proceedings or as required by applicable law. 

(e) Attorneys’ Fees and Costs. Except as provided by applicable law, Employer and Employee shall equally pay the arbitrator’s
fees, arbitration expenses and any other costs unique to the arbitration proceeding. All other costs, expenses and attorneys’ fees shall be borne by the party incurring them. Any postponement or cancellation fee imposed by the arbitration
service will be paid by the party requesting the postponement or cancellation, unless the arbitrator determines otherwise. Any other fees charged or imposed by JAMS or the arbitrator shall be paid as directed by JAMS or the arbitrator, as
applicable. The arbitrator shall award attorneys’ fees, costs and other expenses of arbitration to the prevailing party in the manner and to the extent authorized by applicable law. At the conclusion of the arbitration, each party agrees to pay
promptly any arbitration award imposed against that party. 
 (f) Remedy. Except as provided by the JAMS rules or this Agreement,
arbitration shall be the sole, exclusive and final remedy for any dispute between Employee and Employer. Accordingly, except as provided for by the JAMS rules or this Agreement, neither Employee nor Employer will be permitted to pursue court
action regarding claims that are subject to arbitration and THE PARTIES HEREBY WAIVE THEIR RIGHT TO HAVE ANY DISPUTE, CLAIM OR CONTROVERSY DECIDED BY A JUDGE OR JURY IN A COURT. 

BY SIGNING THIS AGREEMENT, THE PARTIES FURTHER AGREE THAT EACH MAY BRING OR PURSUE CLAIMS AGAINST THE OTHER ONLY IN THEIR INDIVIDUAL CAPACITIES, AND MAY
NOT BRING OR PURSUE CLAIMS OR ACT AS A PLAINTIFF, CLASS MEMBER OR REPRESENTATIVE IN ANY PURPORTED CLASS, REPRESENTATIVE OR COLLECTIVE PROCEEDING, SUBJECT TO AND CONSISTENT WITH APPLICABLE LAW. THE PARTIES FURTHER AGREE THAT THE ARBITRATOR MAY
NOT PRESIDE OVER ANY FORM OF A REPRESENTATIVE OR CLASS PROCEEDING. NOTWITHSTANDING THE FORGOING, NOTHING IN THIS AGREEMENT PREVENTS EITHER PARTY FROM PURSUING A REPRESENTATIVE OR COLLECTIVE ACTION IN COURT THAT MAY NOT BE COMPELLED TO
ARBITRATION AS A MATTER OF LAW. 
 15. Consent to Jurisdiction. In any proceeding seeking equitable relief, to enforce arbitration
or an arbitral award, or in the event that arbitration cannot be enforced, each of the parties hereby irrevocably and unconditionally agrees to submit to the exclusive jurisdiction of the appropriate state and federal courts situated in San Diego,
California in any dispute, controversy, suit or action arising out of or in connection with this Agreement or any associated agreement or document and hereby waives in advance any objection or defense to such jurisdiction, including any defense
based on lack of personal jurisdiction or forum non conveniens. Each of the parties hereby acknowledges that it is the intent of all parties hereto that any judgment, order or decree of any such court may be enforced in any court or other
tribunal of competent jurisdiction in the United States of America or any other jurisdiction throughout the world and hereby waives and agrees not to assert any defense to the enforcement of any such judgment, order or decree in any such court or
tribunal. 
 16. Withholding Taxes. All payments made under this Agreement shall be subject to reduction to reflect taxes or other
charges required to be withheld by law. 

  
 -14- 

 17. Severability. It is the desire and intent of the parties that the provisions of
this Agreement be enforced to the fullest extent permissible under the law and public policies applied in each jurisdiction in which enforcement is sought. Accordingly, in the event that any provision of this Agreement would be held in any
jurisdiction to be invalid, prohibited or unenforceable for any reason, such provision, as to such jurisdiction, shall be ineffective, without invalidating the remaining provisions of this Agreement or affecting the validity or enforceability of
such provision in any jurisdiction. Notwithstanding the foregoing, if such provision could be more narrowly drawn so as not be invalid, prohibited or unenforceable in such jurisdiction, it shall, as to such jurisdiction, be so narrowly drawn,
without invalidating the remaining provisions of this Agreement or affecting the validity or enforceability of such provision in any other jurisdiction. 

18. Amendments, Modifications and Waivers. The terms and provisions of this Agreement may not be modified or amended, nor may any
of the provisions hereof be waived, temporarily or permanently, except pursuant to a written instrument in ink executed by the parties hereto. Any waiver shall not operate or be construed as a waiver of any subsequent breach by another party. 

19. Successors and Assigns. The provisions of this Agreement shall be binding upon and inure to the benefit of the parties and their
respective successors and assigns; provided, that no party may assign, delegate or otherwise transfer any of its rights or obligations under this Agreement without the written consent of each other party, except that Employer may assign and
transfer all or any portion of its rights and obligations under this Agreement to any of its affiliates; provided, however, that no such assignment shall affect Employer’s obligations under this Agreement. Any attempted assignment
in violation of this Section shall be void. This Agreement is personal in nature as to Employee and may not be assigned by him. The parties agree that this Agreement shall survive Employee’s employment by Employer and is binding upon
Employee’s heirs and legal representatives, and that Employer is an express third party beneficiary of this Agreement. 
 20.
Captions. The captions are included in this Agreement for convenience of reference only and shall be ignored in the construction or interpretation of this Agreement. 

21. Counterparts. This Agreement may be signed in any number of counterparts, each of which shall be an original, with the same effect
as if such signatures were upon the same instrument. A facsimile, photocopied signature (which may be delivered by facsimile) or email with scan attachment shall be deemed to be the functional equivalent of an original for all purposes. This
Agreement shall become effective when each party has received a counterpart of this Agreement signed by the other party. 
 22. Entire
Agreement. This Agreement constitutes the entire agreement among the parties hereto with respect to the subject matters addressed herein and supersedes any prior understandings, agreements or representations, by or among such parties, whether
written or oral. 
 23. Construction. The parties have participated jointly, with counsel of their own choosing, in the negotiation
and drafting of this Agreement. If an ambiguity or question of intent or interpretation arises, this Agreement will be construed as if drafted jointly by the parties and no presumption or burden of proof will arise favoring or disfavoring any party
because of the authorship of any provision of this Agreement. 

  
 -15- 

 24. Acknowledgment. Employee acknowledges that he has had the opportunity to consult
with independent counsel of his own choice concerning this Agreement, and that he has taken advantage of that opportunity to the extent that he desires. Employee further acknowledges that he has read and understands this Agreement, is fully aware of
its legal effect, and has entered into it voluntarily based on his own judgment. 
 [Signature page follows] 

  
 -16- 

 IN WITNESS WHEREOF, the undersigned have executed this Agreement as of the date first
written above. 
  

									
	Richard W. Pascoe	 		 	Histogen Inc.
					
	By:	 	 /s/ Richard W. Pascoe
	 		 	By:	 	 /s/ Stephen Chang

		 		 		 		 	Name: Stephen Chang
		 		 		 		 	Title: Chairman

  

  
 Signature Page to
Executive Employment Agreement 

 Schedule 1 

Pre-Approved Boards 

KemPharm Inc (public) 
 Seelos Therapeutics (public) 

Biocom (Trade Association) 
 Johnny Mac Soldiers Fund (non-profit) 

  
 Schedule 1 

 EXHIBIT A 

DEFINITIONS 
 For
purposes of this Exhibit A only, “Employer” means Employer and its affiliates. 
 A. “Trade Secrets”
are defined as information of Employer, including, but not limited to, a formula, pattern, compilation, program, device, method, technique, or process, that: (1) derives independent economic value, actual or potential, from not being generally
known to the public or to other persons who can obtain economic value from its disclosure or use, and (2) is the subject of efforts that are reasonable under the circumstances to maintain its secrecy. 

B. “Records” include, but are not limited to, all books and records of Employer and its subsidiaries, including all accounting
(including accounting work papers), financial reporting, tax, business, marketing, environmental, legal, corporate and other files, documents, instruments and papers, whether originals, copies (including computer generated, recorded or stored
records) or otherwise, customer lists, advertising and promotional materials, financial statements, budgets, projections, financial, tax and accounting records, personnel records, compliance records, ledgers, journals, deeds, legal documents, title
policies, manuals, minute books, stock certificates and books, stock transfer ledgers, contracts, franchises, permits, licenses, reports, management information systems, computer tapes, discs and other files, retrieval programs, operating data or
plans and environmental studies. 
 C. “Confidential Information” is defined as Employer’s Trade Secrets, Records and
other proprietary information relating to Employer’s businesses, business methods, personnel and customers. 
 D. Notwithstanding
anything to the contrary as set forth in this Exhibit A, Trade Secrets, Records or Confidential Information shall not include information that: (a) is already available to and known by third parties in the public domain through no fault
of Employee, (b) becomes available to and known by third parties in the public domain through no fault of Employee, or (c) is obtained by Employee from a third party not under confidentiality obligations and without a breach of any
obligations of confidentiality. 

  
 Exhibit A 

 EXHIBIT B 

CALIFORNIA LABOR CODE SECTIONS 

2870. (a) Any provision in an employment agreement which provides that an employee shall assign, or offer to assign, any of his or her rights in an invention
to his or her employer shall not apply to an invention that the employee developed entirely on his or her own time without using the employer’s equipment, supplies, facilities, or trade secret information except for those inventions that
either: 
 (1) Relate at the time of conception or reduction to practice of the invention to the employer’s business, or actual or demonstrably
anticipated research or development of the employer; or 
 (2) Result from any work performed by the employee for the employer. 

(b) To the extent a provision in an employment agreement purports to require an employee to assign an invention otherwise excluded from being required to be
assigned under subdivision (a), the provision is against the public policy of this state and is unenforceable. 
 2871. No employer shall require a
provision made void and unenforceable by Section 2870 as a condition of employment or continued employment. Nothing in this article shall be construed to forbid or restrict the right of an employer to provide in contracts of employment for
disclosure, provided that any such disclosures be received in confidence, of all of the employee’s inventions made solely or jointly with others during the term of his or her employment, a review process by the employer to determine such issues
as may arise, and for full title to certain patents and inventions to be in the United States, as required by contracts between the employer and the United States or any of its agencies. 

2872. If an employment agreement entered into after January 1, 1980, contains a provision requiring the employee to assign or offer to assign any of his
or her rights in any invention to his or her employer, the employer must also, at the time the agreement is made, provide a written notification to the employee that the agreement does not apply to an invention which qualifies fully under the
provisions of Section 2870. In any suit or action arising thereunder, the burden of proof shall be on the employee claiming the benefits of its provisions. 

  
 Exhibit B 

 EXHIBIT C 

RELEASE 
 See
attached. 

  
 Exhibit C 

 CONFIDENTIAL SEVERANCE AGREEMENT AND GENERAL RELEASE 

This Confidential Severance Agreement and General Release (the “Agreement”) is entered into by and between Richard W. Pascoe
(“Employee”) and Histogen Inc. (the “Company”) (each a “Party” and collectively the “Parties”). 

WHEREAS, the Employee signed an Executive Employment Agreement with the Company on [______________] (the “Employment
Agreement”), the Employee has been employed by the Company on an at-will basis since on or about [____________]; 

WHEREAS, the Employee’s employment, positions and offices with the Company have terminated effective ____________, 20[ ] (the
“Separation Date”); and 
 WHEREAS, the Parties wish to resolve any and all disputes, claims, complaints,
grievances, charges, actions, petitions, and demands that the Employee may have against the Company and any of the Company Releasees as defined below, including, but not limited to, any and all claims arising out of or in any way related to the
Employee’s employment with or separation from the Company. 
 NOW, THEREFORE, the Company and the Employee, for good and
valuable consideration receipt of which is hereby acknowledged, hereby agree as follows: 
 1. Separation of Employment; Stock Options; Benefits. 

(a) Separation of Employment. The Employee’s employment with the Company ended, and the Employee shall be deemed to have separated
from any and all offices and positions with the Company and with any of its related entities, for all purposes, on the Separation Date. The Employee acknowledges and represents that, other than the consideration set forth in this Agreement, the
Company has paid or provided all salary, wages, bonuses, accrued vacation/paid time off, premiums, leaves, housing allowances, relocation costs, interest, severance, outplacement costs, fees, reimbursable expenses, commissions, stock, stock options,
vesting, and any and all other benefits and compensation due to the Employee 
 (b) Stock Options. Employee was granted options to
purchase shares of common stock of the Company as set forth on Exhibit A1 hereto (the “Option Awards”), pursuant to the Company’s [____________] Plan (the
“Plan”) and the stock option agreement thereunder (the “Option Agreement”). The Employee acknowledges and agrees that the Option Awards are the only stock options or other capital stock of the Company that Employee
has received. All vesting of the Option Awards ceased as of the Separation Date and all unvested stock options under the Option Awards were immediately forfeited on the Separation Date. Any vested, but unexercised, stock options under the Option
Awards will continue to be subject to the Plan and the Option Agreement. The Employee further acknowledges that he may exercise any outstanding vested, and unexercised, stock options under the Option Awards at any time within his applicable
post-termination exercise period for each Option Award (which post-termination exercise period is set forth on Exhibit A). If the Employee does not exercise his vested stock options under the Option Awards by the end of the applicable
post-termination exercise period, then any such unexercised stock options will terminate. 
  

	1 	 NTD: Exhibit A to include list of each stock option grant, number of shares vested and unvested as of the
Separation Date, and the post-termination exercise period. Section to be revised if accelerated vesting is part of severance. 

  
 Exhibit C 

-1- 

 (c) Benefits. The Employee’s health insurance benefits shall cease on
[____________]2, subject to the Employee’s right to continue his health insurance under COBRA (as defined herein), provided the Employee timely elects continuation coverage pursuant to the
Consolidated Omnibus Budget Reconciliation Act of 1985, as amended (“COBRA”), within the time period prescribed pursuant to COBRA. The Employee’s participation in all benefits and incidents of employment, including, but not
limited to, vesting in stock options, and the accrual of bonuses, vacation, and paid time off, ceased as of the Separation Date. The Company will provide the Employee with a COBRA notice within the time period by law. 

2. Severance. In consideration for Employee signing this Agreement, and subject to the conditions set forth below, provided Employee does not revoke
Employee’s acceptance in the manner set forth in paragraph 5, Employee will receive the following severance benefits (“Severance”): 

(a) Severance Payment. Employee will be paid the severance described in Section 8(__) of the Employment Agreement pursuant to the
terms of the Employment Agreement. 
 (b) Conditions. Employee agrees that Employee’s full compliance in all respects with each
and every term of this Agreement, including without limitation, the obligations set forth in paragraphs 4 and 5, is an express condition to the Company’s obligation to provide the Severance set forth herein. 

3. Release. Employee, and Employee’s successors, heirs, agents, and assigns, release and forever discharge the Company and its current and former
parent companies, subsidiaries, agents, employees, officers, directors, owners, executives, trustees, representatives, attorneys, related organizations, assigns, and successors (hereafter referred to collectively as the “Released
Parties”), and each of them, from any and all liabilities, claims, causes of action, charges, complaints, commissions, obligations, costs, losses, damages, injuries, attorneys’ fees, and other legal responsibilities, of any form
whatsoever, whether known or unknown, unforeseen, unanticipated, unsuspected or latent, that Employee has incurred or expects to incur, or now owns or holds, or has at any time heretofore owned or held, or may at any time own, hold, or claim to hold
by reason of any matter or thing arising from any cause whatsoever prior to the date of Employee’s execution of this Agreement, including but not limited to Employee’s employment with the Company, and the termination of that employment.

 This release extends to any and all claims including, but not limited to, any alleged: (a) violation of the California Fair
Employment and Housing Act, the California Wage Orders, the Private Attorneys General Act, the Employee Retirement Income Security Act of 1974, Title VII of the Civil Rights Act, the Age Discrimination in Employment Act, the Worker Adjustment and
Retraining Notification Act, the California Labor Code, the California Government Code, the Fair Labor Standards Act, the Occupational Safety and Health Act, the Consolidated Omnibus Budget Reconciliation Act of 1985, the Americans With Disabilities
Act, the Family Medical Leave Act, the California Family Rights Act, the California Business and Professions Code, and/or state and federal False Claims acts; (b) discrimination, harassment, retaliation, breach of any express or implied
employment contract or agreement, wrongful discharge, breach of the implied covenant of good faith and fair dealing, intentional or negligent infliction of emotional distress, misrepresentation, fraud, defamation, interference with prospective
economic advantage, and/or failure to pay wages due or other monies owed; and (c) violation of any local, state or federal law, regulation, ordinance, and/or public policy, violation of any contract, or tort or common law claim having any
bearing whatsoever on the terms and conditions and/or cessation of employment with any of the Released Parties. Notwithstanding the releases set forth above, this Agreement does not release any claim that is prohibited from being released as a
matter of law. 
 Employee understands that nothing in this release prevents Employee from filing a charge or complaint with or from
participating in an investigation or proceeding conducted by the Equal Employment Opportunity Commission (“EEOC”), National Labor Relations Board, or any other federal, state, or local agency charged with the enforcement of any
employment laws, although Employee understands that by 
  
  

	2 	 NTD: To be Separation Date or such other date in accordance with the Company health benefit plan.

  
 Exhibit C 

-2- 

 
signing this Agreement, Employee waives the right to recover any damages or to receive other relief in any claim or suit brought by or through the EEOC, or any other state or local deferral
agency on Employee’s behalf. This Agreement also does not affect Employee’s right to report a violation of securities laws or participate in an investigation conducted by the U.S. Securities and Exchange Commission. 

4. Section 1542. Employee expressly waives any and all rights that Employee may have under Section 1542 of the Civil Code of the State of
California, which states, in part: “A GENERAL RELEASE DOES NOT EXTEND TO CLAIMS WHICH THE CREDITOR DOES NOT KNOW OR SUSPECT TO EXIST IN HIS OR HER FAVOR AT THE TIME OF EXECUTING THE RELEASE, WHICH IF KNOWN BY HIM OR HER MUST HAVE MATERIALLY
AFFECTED HIS OR HER SETTLEMENT WITH THE DEBTOR.” Employee expressly waives and releases any and all right to benefits that Employee may have under California Civil Code § 1542, to the fullest extent Employee may do so lawfully.
Employee further acknowledges that Employee may later discover facts different from or in addition to those facts now known to Employee or believed by Employee to be true with respect to any or all of the matters covered by this Agreement, and
Employee agrees that this Agreement nevertheless shall remain in full and complete force and effect. 
 5. Older Worker’s Benefit Protection Act.
This Agreement constitutes a knowing and voluntary waiver of any and all rights or claims that Employee has or may have under the Federal Age Discrimination In Employment Act, as amended by the Older Workers’ Benefit Protection Act of 1990,
29 U.S.C. §§ 621 et seq. This paragraph and this Agreement are written in a manner calculated to be understood by Employee. Employee is hereby advised in writing to consult with an attorney before signing this
Agreement. Employee acknowledges that, in return for this Agreement, Employee will receive consideration beyond that which Employee was already entitled to receive before entering into this Agreement. Employee acknowledges that Employee has had a
reasonable time of up to 21 days in which to consider this Agreement, as required by the Older Workers’ Benefits Protection Act. If Employee decides not to use all 21 days, Employee knowingly and voluntarily waives any claims that Employee
was not given the 21-day period or did not use the entire 21 days to consider this Agreement. Employee may revoke this Agreement at any time within the 7-day period
following the date Employee signs this Agreement by providing written notice of revocation to the Company. This Agreement shall not become effective or enforceable until 12:01 a.m. on the 8th day after Employee signs the Agreement. 

6. No Admissions. Neither this Agreement nor the furnishing of the consideration for this Agreement shall be deemed or construed as an admission of
liability or wrongdoing on the part of the Released Parties, nor shall this Agreement or the furnishing of the consideration for this Agreement be admissible as evidence in any proceeding other than for the enforcement of this Agreement. 

7. Indemnification. No Party or attorney for any Party has made any representations or warranties regarding the taxability of the monetary payment made
herein. Employee will assume all risks regarding the tax consequences of the monetary payment to Employee, if any. Employee agrees to indemnify and hold harmless the Released Parties against any assessment of payroll, withholding, FICA, or other
taxes or penalties to Employee on said payment, if any. 
 8. Further Claims. Employee has not and will not file any charges against any of the
Released Parties based upon, arising out of, or relating to any claim, demand, or cause of action released herein. Employee has not and will not institute a lawsuit in any state or federal court, based upon, arising out of, or relating to any claim,
demand, or cause of action released herein. Employee has not and will not participate, assist, or cooperate in any claim, charge, suit, complaint, action or proceeding against any of the Released Parties, unless and to the extent required or
compelled by law. Employee has not and will not encourage and/or solicit any third party to file any claim, charge, suit, complaint, action or proceeding against any of the Released Parties. This provision does not apply to claims challenging the
validity of the Agreement under the Age Discrimination in Employment Act or any other charges or rights that cannot be waived as a matter of law. 

  
 Exhibit C 

-3- 

 9. Further Payments. Employee acknowledges that the Company has already provided Employee with
payment for any and all wages, compensation, commissions, vacation, sick leave, overtime, expenses, options, bonuses, profit sharing, benefits, insurance, and/or any other form of payment from the Released Parties arising out of or related in any
way to Employee’s employment with the Company. 
 10. Workplace Injuries. Employee represents and acknowledges that Employee has not sustained
any workplace injury of any kind during Employee’s employment with the Company, and Employee does not intend to file any claim or seek any benefits of any kind under workers’ compensation. 

11. Prior Agreements. This Agreement does not alter, modify or impact the confidentiality provisions and the restrictive covenants set forth in any
prior agreements between the Parties, including, without limitation, the provisions in the Employment Agreement regarding nondisclosure of the Company’s Trade Secrets and Confidential Information (as defined therein), ongoing nonsolicitation
and nondisparagement obligations and all other ongoing or post-employment obligations therein or in any other agreement with or for the benefit of the Company, which shall continue in full force and effect, nor does it affect Employee’s
obligation to comply with those provisions and covenants. 
 12. Rehire. Employee agrees that Employee will not seek reemployment with the Company or
employment with the Released Parties, and acknowledges that such entities have no obligation to employ, hire, rehire, or consider Employee for hire. Employee’s forbearance from seeking employment with the Released Parties is purely contractual
and voluntary, and does not constitute discrimination or retaliation in any respect. Employee agrees that in the event such employment occurs in the future, this provision shall serve as good and just cause for termination of that employment.
Employee knowingly and voluntarily waives all rights Employee may have under federal and/or state law to reinstatement of Employee’s employment with the Company or the Released Parties. 

13. Miscellaneous. Employee has full authority to enter into this Agreement and to be bound by it. Employee is voluntarily entering into this Agreement
free of any duress or coercion. Employee was advised to and has had the opportunity to consult legal counsel of Employee’s own choosing with respect to the execution and legal effect of this Agreement. This Agreement constitutes the entire
agreement between the Parties and supersedes any and all other agreements or understandings, either oral or written, between the Parties with respect to the subject matter hereof, provided that Employee must continue to comply with the agreements
referenced in Paragraph 11 herein. Each Party to this Agreement acknowledges that no representations, inducements, promises, or other agreements have been made by or on behalf of any Party except those covenants, agreements and promises embodied in
this Agreement. This Agreement cannot be modified in any respect except in a written instrument signed by the Parties. In the event that any provision of this Agreement is held to be void, null or unenforceable, the remaining portions will remain in
full force and effect. Any uncertainty or ambiguity in the Agreement will not be construed for or against any Party based on the attribution of drafting to any Party. This Agreement may be executed by the Parties in any number of counterparts, which
are defined as duplicate originals, all of which taken together will be construed as one document. A faxed or .pdf copy of this Agreement may be deemed an original. This Agreement will be construed and governed by the laws of the State of
California. 
 14. Attorneys’ Fees and Costs For Legal Proceedings. If any party to this Agreement is required to enforce any term of this
Agreement in any proceeding, the prevailing party shall be entitled to all reasonable attorneys’ fees and costs expended to enforce this Agreement, in addition to any other relief to which the prevailing party may be entitled. 

  
 Exhibit C 

-4- 

 PLEASE READ CAREFULLY, THIS AGREEMENT INCLUDES A RELEASE OF ALL 

KNOWN AND UNKNOWN CLAIMS. 
  

							
	DATED:                             	 		 	  

		 		 	Richard W. Pascoe
			
		 		 	Histogen Inc.
				
	DATED:                             	 		 	By	  	              

				
		 		 	Title:	  	              

  
 Exhibit C 

-5-

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