Document:

EX-10.4

 Exhibit 10.4 

CONTRAFECT CORPORATION 

INDEMNIFICATION AGREEMENT 

This Indemnification Agreement (“Agreement”) is made as of             ,
201     by and between ContraFect Corporation, a Delaware corporation (the “Company”), and             (“Indemnitee”). This Agreement supersedes and
replaces any and all previous Agreements between the Company and Indemnitee covering the subject matter of this Agreement. 
 RECITALS

 WHEREAS, highly competent persons have become more reluctant to serve publicly held corporations as directors or officers or in other
capacities unless they are provided with adequate protection through insurance or adequate indemnification against inordinate risks of claims and actions against them arising out of their service to and activities on behalf of the corporation; 

WHEREAS, the Board of Directors of the Company (the “Board”) has determined that, in order to attract and retain qualified
individuals, the Company will attempt to maintain on an ongoing basis, at its sole expense, liability insurance to protect persons serving the Company from certain liabilities. The Bylaws (the “Bylaws”) of the Company and the Certificate
of Incorporation of the Company (“the Certificate of Incorporation”) require indemnification of the officers and directors of the Company. Indemnitee may also be entitled to indemnification pursuant to the General Corporation Law of the
State of Delaware (the “DGCL”). The Bylaws and the Certificate of Incorporation and the DGCL expressly provide that the indemnification provisions set forth therein are not exclusive, and thereby contemplate that contracts may be entered
into between the Company and members of the board of directors, officers and other persons with respect to indemnification; 
 WHEREAS, the
uncertainties relating to such insurance and to indemnification have increased the difficulty of attracting and retaining such persons; 

WHEREAS, the Board has determined that the increased difficulty in attracting and retaining such persons is detrimental to the best interests
of the Company and its stockholders and that the Company should act to assure such persons that there will be increased certainty of such protection in the future; 

WHEREAS, it is reasonable, prudent and necessary for the Company to contractually obligate itself to indemnify, and to advance expenses on
behalf of, such persons to the fullest extent permitted by applicable law so that they will serve or continue to serve the Company free from undue concern that they will not be so indemnified; 

WHEREAS, this Agreement is a supplement to and in furtherance of the Bylaws and the Certificate of Incorporation and any resolutions adopted
pursuant thereto, and shall not be deemed a substitute therefor, nor to diminish or abrogate any rights of Indemnitee thereunder; 

WHEREAS, Indemnitee does not regard the protection available under the Bylaws and insurance as adequate in the present circumstances, and may
not be willing to serve as an officer or director without adequate protection, and the Company desires Indemnitee to serve in such capacity. Indemnitee is willing to serve, continue to serve and to take on additional service for or on behalf of the
Company on the condition that he be so indemnified; and 
 NOW, THEREFORE, in consideration of the premises and the covenants contained
herein, the Company and Indemnitee do hereby covenant and agree as follows: 
 Section 1. Services to the Company. Indemnitee
agrees to serve as a [director] [officer] [employee] [agent] of the Company. Indemnitee may at any time and for any reason resign from such position (subject to any other contractual obligation or any obligation imposed by operation of law), in
which event the Company shall have no obligation under this Agreement to keep Indemnitee in such position. This Agreement shall not be deemed an employment contract between the Company and Indemnitee. Indemnitee specifically acknowledges that
Indemnitee’s employment with the Company, if any, is at will, and the Indemnitee may be discharged at any time for any reason, with or without cause, except as may be otherwise provided in any written employment contract between Indemnitee and
the Company, other applicable formal severance policies duly adopted by the Board, or, with respect to service as a director or officer of the Company, by the Certificate of Incorporation, the Bylaws, and the DGCL. The foregoing notwithstanding,
this Agreement shall continue in force after Indemnitee has ceased to serve as an [officer] [director] [employee] [agent] of the Company. 

 Section 2. Definitions. As used in this Agreement: 

(a) References to “agent” shall mean any person who is or was a director, officer, or employee of the Company or other person
authorized by the Company to act for the Company, to include such person serving in such capacity as a director, officer, employee, fiduciary or other official of another corporation, partnership, limited liability company, joint venture, trust or
other Enterprise at the request of, for the convenience of, or to represent the interests of the Company. 
 (b) A “Change in
Control” shall be deemed to occur upon the earliest to occur after the date of this Agreement of any of the following events: 
 i.
Acquisition of Stock by Third Party. Any Person (as defined below) is or becomes the Beneficial Owner (as defined below), directly or indirectly, of securities of the Company representing more than fifty percent (50%) or more of the combined
voting power of the Company’s then outstanding securities; 
 ii. Change in Board. During any period of two (2) consecutive
years (not including any period prior to the execution of this Agreement), individuals who at the beginning of such period constitute the Board, and any new director (other than a director designated by a person who has entered into an agreement
with the Company to effect a transaction described in Sections 2(b)(i), 2(b)(iii) or 2(b)(iv)) whose election by the Board or nomination for election by the Company’s stockholders was approved by a vote of at least two-thirds (2/3) of
the directors then still in office who either were directors at the beginning of the period or whose election or nomination for election was previously so approved, cease for any reason to constitute at least a majority of the members of the Board;

 iii. Corporate Transactions. The effective date of a merger or consolidation of the Company with any other entity, other than a merger or
consolidation which would result in the voting securities of the Company outstanding immediately prior to such merger or consolidation continuing to represent (either by remaining outstanding or by being converted into voting securities of the
surviving entity) more than 51% of the combined voting power of the voting securities of the surviving entity outstanding immediately after such merger or consolidation and with the power to elect at least a majority of the board of directors or
other governing body of such surviving entity; 
 iv. Liquidation. The approval by the stockholders of the Company of a complete liquidation
of the Company or an agreement for the sale or disposition by the Company of all or substantially all of the Company’s assets; and 

v. Other Events. There occurs any other event of a nature that would be required to be reported in response to Item 6(e) of
Schedule 14A of Regulation 14A (or a response to any similar item on any similar schedule or form) promulgated under the Exchange Act (as defined below), whether or not the Company is then subject to such reporting requirement. 

For purposes of this Section 2(b), the following terms shall have the following meanings: 

(A) “Exchange Act” shall mean the Securities Exchange Act of 1934, as amended from time to time. 

(B) “Person” shall have the meaning as set forth in Sections 13(d) and 14(d) of the Exchange Act; provided,
however, that Person shall exclude (i) the Company, (ii) any trustee or other fiduciary holding securities under an employee benefit plan of the Company, and (iii) any corporation owned, directly or indirectly, by the stockholders of
the Company in substantially the same proportions as their ownership of stock of the Company. 
 (C) “Beneficial
Owner” shall have the meaning given to such term in Rule 13d-3 under the Exchange Act; provided, however, that Beneficial Owner shall exclude any Person otherwise becoming a Beneficial Owner by reason of the stockholders of the Company
approving a merger of the Company with another entity. 
 (c) “Corporate Status” describes the status of a person who is or
was a director, officer, employee or agent of the Company or of any other corporation, limited liability company, partnership or joint venture, trust, employee benefit plan or other enterprise which such person is or was serving at the request of
the Company. 
 (d) “Disinterested Director” means a director of the Company who is not and was not a party to the Proceeding
in respect of which indemnification is sought by Indemnitee. 
 (e) “Enterprise” shall mean the Company and any other
corporation, limited liability company, partnership, joint venture, trust, employee benefit plan or other enterprise of which Indemnitee is or was serving at the request of the Company as a director, officer, employee, agent or fiduciary. 

 (f) “Expenses” shall include all reasonable attorneys’ fees, retainers, court
costs, transcript costs, fees of experts, witness fees, travel expenses, duplicating costs, printing and binding costs, telephone charges, postage, delivery service fees, any federal, state, local or foreign taxes imposed on Indemnitee as a result
of the actual or deemed receipt of any payments under this Agreement, ERISA excise taxes and penalties, and all other disbursements or expenses of the types customarily incurred in connection with prosecuting, defending, preparing to prosecute or
defend, investigating, being or preparing to be a witness in, or otherwise participating in, a Proceeding. Expenses also shall include (i) Expenses incurred in connection with any appeal resulting from any Proceeding, including without
limitation the premium, security for, and other costs relating to any cost bond or other appeal bond or its equivalent, and (ii) for purposes of Section 14(d) only, Expenses incurred by Indemnitee in connection with the interpretation,
enforcement or defense of Indemnitee’s rights under this Agreement, by litigation or otherwise. The parties agree that for the purposes of any advancement of Expenses for which Indemnitee has made written demand to the Company in accordance
with this Agreement, all Expenses included in such demand that are certified by affidavit of Indemnitee’s counsel as being reasonable shall be presumed conclusively to be reasonable. Expenses, however, shall not include amounts paid in
settlement by Indemnitee or the amount of judgments or fines against Indemnitee. 
 (g) “Independent Counsel” means a law firm, or
a member of a law firm, that is experienced in matters of corporation law and neither presently is, nor in the past five years has been, retained to represent: (i) the Company or Indemnitee in any matter material to either such party
(other than with respect to matters concerning the Indemnitee under this Agreement, or of other indemnitees under similar indemnification agreements), or (ii) any other party to the Proceeding giving rise to a claim for indemnification
hereunder. Notwithstanding the foregoing, the term “Independent Counsel” shall not include any person who, under the applicable standards of professional conduct then prevailing, would have a conflict of interest in representing either the
Company or Indemnitee in an action to determine Indemnitee’s rights under this Agreement. The Company agrees to pay the reasonable fees and expenses of the Independent Counsel referred to above and to fully indemnify such counsel against any
and all Expenses, claims, liabilities and damages arising out of or relating to this Agreement or its engagement pursuant hereto. 
 (h) The
term “Proceeding” shall include any threatened, pending or completed action, suit, arbitration, alternate dispute resolution mechanism, investigation, inquiry, administrative hearing or any other actual, threatened or completed proceeding,
whether brought in the right of the Company or otherwise and whether of a civil, criminal, administrative legislative, or investigative (formal or informal) nature, including any appeal therefrom, in which Indemnitee was, is or will be involved as a
party, potential party, non-party witness or otherwise by reason of the fact that Indemnitee is or was a director or officer of the Company, by reason of any action taken by him or of any action on his part while acting as director or officer of the
Company, or by reason of the fact that he is or was serving at the request of the Company as a director, officer, employee or agent of another corporation, limited liability company, partnership, joint venture, trust or other enterprise, in each
case whether or not serving in such capacity at the time any liability or expense is incurred for which indemnification, reimbursement, or advancement of expenses can be provided under this Agreement. If the Indemnitee believes in good faith that a
given situation may lead to or culminate in the institution of a Proceeding, this shall be considered a Proceeding under this paragraph. 

(i) Reference to “other enterprise” shall include employee benefit plans; references to “fines” shall include any
excise tax assessed with respect to any employee benefit plan; references to “serving at the request of the Company” shall include any service as a director, officer, employee or agent of the Company which imposes duties on, or involves
services by, such director, officer, employee or agent with respect to an employee benefit plan, its participants or beneficiaries; and a person who acted in good faith and in a manner he reasonably believed to be in the best interests of the
participants and beneficiaries of an employee benefit plan shall be deemed to have acted in a manner “not opposed to the best interests of the Company” as referred to in this Agreement. 

Section 3. Indemnity in Third-Party Proceedings. The Company shall indemnify Indemnitee in accordance with the provisions of this
Section 3 if Indemnitee is, or is threatened to be made, a party to or a participant in any Proceeding, other than a Proceeding by or in the right of the Company to procure a judgment in its favor. Pursuant to this Section 3, Indemnitee
shall be indemnified to the fullest extent permitted by applicable law against all Expenses, judgments, fines and amounts paid in settlement actually and reasonably incurred by Indemnitee or on his behalf in connection with such Proceeding or any
claim, issue or matter therein, if Indemnitee acted in good faith and in a manner he reasonably believed to be in or not opposed to the best interests of the Company and, in the case of a criminal proceeding had no reasonable cause to believe that
his conduct was unlawful. The parties hereto intend that this Agreement shall provide to the fullest extent permitted by law for indemnification in excess of that expressly permitted by statute, including, without limitation, any indemnification
provided by the Certificate of Incorporation, the Bylaws, vote of the Company’s stockholders or disinterested directors or applicable law. 

 Section 4. Indemnity in Proceedings by or in the Right of the Company. The Company
shall indemnify Indemnitee in accordance with the provisions of this Section 4 if Indemnitee is, or is threatened to be made, a party to or a participant in any Proceeding by or in the right of the Company to procure a judgment in its favor.
Pursuant to this Section 4, Indemnitee shall be indemnified to the fullest extent permitted by applicable law against all Expenses actually and reasonably incurred by him or on his behalf in connection with such Proceeding or any claim, issue
or matter therein, if Indemnitee acted in good faith and in a manner he reasonably believed to be in or not opposed to the best interests of the Company. No indemnification for Expenses shall be made under this Section 4 in respect of any
claim, issue or matter as to which Indemnitee shall have been finally adjudged by a court to be liable to the Company, unless and only to the extent that the Delaware Court of Chancery or any court in which the Proceeding was brought shall determine
upon application that, despite the adjudication of liability but in view of all the circumstances of the case, Indemnitee is fairly and reasonably entitled to indemnification. 

Section 5. Indemnification for Expenses of a Party Who is Wholly or Partly Successful. Notwithstanding any other provisions of
this Agreement, to the fullest extent permitted by applicable law and to the extent that Indemnitee is a party to (or a participant in) and is successful, on the merits or otherwise, in any Proceeding or in defense of any claim, issue or matter
therein, in whole or in part, the Company shall indemnify Indemnitee against all Expenses actually and reasonably incurred by him in connection therewith. If Indemnitee is not wholly successful in such Proceeding but is successful, on the merits or
otherwise, as to one or more but less than all claims, issues or matters in such Proceeding, the Company shall indemnify Indemnitee against all Expenses actually and reasonably incurred by him or on his behalf in connection with or related to each
successfully resolved claim, issue or matter to the fullest extent permitted by law. For purposes of this Section and without limitation, the termination of any claim, issue or matter in such a Proceeding by dismissal, with or without prejudice,
shall be deemed to be a successful result as to such claim, issue or matter. 
 Section 6. Indemnification For Expenses of a
Witness. Notwithstanding any other provision of this Agreement, to the fullest extent permitted by applicable law and to the extent that Indemnitee is, by reason of his Corporate Status, a witness or otherwise asked to participate in any
Proceeding to which Indemnitee is not a party, he shall be indemnified against all Expenses actually and reasonably incurred by him or on his behalf in connection therewith. 

Section 7. Partial Indemnification. If Indemnitee is entitled under any provision of this Agreement to indemnification by the
Company for some or a portion of Expenses, but not, however, for the total amount thereof, the Company shall nevertheless indemnify Indemnitee for the portion thereof to which Indemnitee is entitled. 

Section 8. Additional Indemnification. 

(a) Notwithstanding any limitation in Sections 3, 4, or 5, the Company shall indemnify Indemnitee to the fullest extent permitted by
applicable law if Indemnitee is a party to or threatened to be made a party to any Proceeding (including a Proceeding by or in the right of the Company to procure a judgment in its favor) against all Expenses, judgments, fines and amounts paid in
settlement actually and reasonably incurred by Indemnitee in connection with the Proceeding. 
 (b) For purposes of Section 8(a),
the meaning of the phrase “to the fullest extent permitted by applicable law” shall include, but not be limited to: 
 i. to the
fullest extent permitted by the provision of the DGCL that authorizes or contemplates additional indemnification by agreement, or the corresponding provision of any amendment to or replacement of the DGCL, and 

ii. to the fullest extent authorized or permitted by any amendments to or replacements of the DGCL adopted after the date of this Agreement
that increase the extent to which a corporation may indemnify its officers and directors. 
 Section 9. Exclusions.
Notwithstanding any provision in this Agreement, the Company shall not be obligated under this Agreement to make any indemnity in connection with any claim made against Indemnitee: 

(a) for which payment has actually been made to or on behalf of Indemnitee under any insurance policy or other indemnity provision, except
with respect to any excess beyond the amount paid under any insurance policy or other indemnity provision; or 
 (b) for (i) an
accounting of profits made from the purchase and sale (or sale and purchase) by Indemnitee of securities of the Company within the meaning of Section 16(b) of the Exchange Act (as defined in Section 2(b) hereof) or similar provisions of
state statutory law or common law, or (ii) any reimbursement of the Company by the Indemnitee of any bonus or other incentive-based or equity-based compensation or of any profits realized by the Indemnitee from the sale of securities of the
Company, as required in each case under the Exchange Act (including any such reimbursements that arise from an accounting restatement of the Company pursuant to Section 304 of the Sarbanes-Oxley Act of 2002 (the “Sarbanes-Oxley Act”),
or the payment to the Company of profits arising from the purchase and sale by Indemnitee of securities in violation of Section 306 of the Sarbanes-Oxley Act); or 

 (c) except as provided in Section 14(d) of this Agreement, in connection with any
Proceeding (or any part of any Proceeding) initiated by Indemnitee, including any Proceeding (or any part of any Proceeding) initiated by Indemnitee against the Company or its directors, officers, employees or other indemnitees, unless (i) the
Board authorized the Proceeding (or any part of any Proceeding) prior to its initiation or (ii) the Company provides the indemnification, in its sole discretion, pursuant to the powers vested in the Company under applicable law. 

Section 10. Advances of Expenses. In accordance with Section 2 of Article VI of the Bylaws, and notwithstanding any
provision of this Agreement to the contrary, the Company shall advance, to the extent not prohibited by law, the Expenses incurred by Indemnitee in connection with any Proceeding, and such advancement shall be made within thirty (30) days
after the receipt by the Company of a statement or statements requesting such advances from time to time, whether prior to or after final disposition of any Proceeding. Advances shall be unsecured and interest free. Advances shall be made without
regard to Indemnitee’s ability to repay the Expenses and without regard to Indemnitee’s ultimate entitlement to indemnification under the other provisions of this Agreement. Advances shall include any and all reasonable Expenses incurred
pursuing an action to enforce this right of advancement, including Expenses incurred preparing and forwarding statements to the Company to support the advances claimed. The Indemnitee shall qualify for advances upon the execution and delivery to the
Company of this Agreement, which shall constitute an undertaking providing that the Indemnitee undertakes to repay the amounts advanced (without interest) to the extent that it is ultimately determined that Indemnitee is not entitled to be
indemnified by the Company. No other form of undertaking shall be required other than the execution of this Agreement. This Section 10 shall not apply to any claim made by Indemnitee for which indemnity is excluded pursuant to Section 9.

 Section 11. Procedure for Notification and Defense of Claim. 

(a) Indemnitee shall notify the Company in writing of any matter with respect to which Indemnitee intends to seek indemnification or
advancement of Expenses hereunder as soon as reasonably practicable following the receipt by Indemnitee of written notice thereof. The written notification to the Company shall include a description of the nature of the Proceeding and the facts
underlying the Proceeding. To obtain indemnification under this Agreement, Indemnitee shall submit to the Company a written request, including therein or therewith such documentation and information as is reasonably available to Indemnitee and is
reasonably necessary to determine whether and to what extent Indemnitee is entitled to indemnification following the final disposition of such action, suit or proceeding. The omission by Indemnitee to notify the Company hereunder will not relieve
the Company from any liability which it may have to Indemnitee hereunder or otherwise than under this Agreement, and any delay in so notifying the Company shall not constitute a waiver by Indemnitee of any rights under this Agreement. The Secretary
of the Company shall, promptly upon receipt of such a request for indemnification, advise the Board in writing that Indemnitee has requested indemnification. 

(b) The Company will be entitled to participate in the Proceeding at its own expense. 

Section 12. Procedure Upon Application for Indemnification. 

(a) Upon written request by Indemnitee for indemnification pursuant to Section 11(a), a determination, if required by applicable law,
with respect to Indemnitee’s entitlement thereto shall be made in the specific case: (i) if a Change in Control shall have occurred, by Independent Counsel in a written opinion to the Board, a copy of which shall be delivered to
Indemnitee; or (ii) if a Change in Control shall not have occurred, (A) by a majority vote of the Disinterested Directors, even if less than a quorum of the Board, (B) by a committee of Disinterested Directors designated by a majority
vote of the Disinterested Directors, even if less than a quorum of the Board, (C) if there are no such Disinterested Directors or, if such Disinterested Directors so direct, by Independent Counsel in a written opinion to the Board, a copy of
which shall be delivered to Indemnitee or (D) if so directed by the Board, by the stockholders of the Company; and, if it is so determined that Indemnitee is entitled to indemnification, payment to Indemnitee shall be made within
ten (10) days after such determination. Indemnitee shall cooperate with the person, persons or entity making such determination with respect to Indemnitee’s entitlement to indemnification, including providing to such person, persons
or entity upon reasonable advance request any documentation or information which is not privileged or otherwise protected from disclosure and which is reasonably available to Indemnitee and reasonably necessary to such determination. Any costs or
Expenses (including attorneys’ fees and disbursements) incurred by Indemnitee in so cooperating with the person, persons or entity making such determination shall be borne by the Company (irrespective of the determination as to
Indemnitee’s entitlement to indemnification) and the Company hereby indemnifies and agrees to hold Indemnitee harmless therefrom. 

 (b) In the event the determination of entitlement to indemnification is to be made by
Independent Counsel pursuant to Section 12(a) hereof, the Independent Counsel shall be selected as provided in this Section 12(b). If a Change in Control shall not have occurred, the Independent Counsel shall be selected by the Board, and
the Company shall give written notice to Indemnitee advising him of the identity of the Independent Counsel so selected. If a Change in Control shall have occurred, the Independent Counsel shall be selected by Indemnitee (unless Indemnitee shall
request that such selection be made by the Board, in which event the preceding sentence shall apply), and Indemnitee shall give written notice to the Company advising it of the identity of the Independent Counsel so selected. In either event,
Indemnitee or the Company, as the case may be, may, within ten (10) days after such written notice of selection shall have been given, deliver to the Company or to Indemnitee, as the case may be, a written objection to such selection;
provided, however, that such objection may be asserted only on the ground that the Independent Counsel so selected does not meet the requirements of “Independent Counsel” as defined in Section 2 of this Agreement, and
the objection shall set forth with particularity the factual basis of such assertion. Absent a proper and timely objection, the person so selected shall act as Independent Counsel. If such written objection is so made and substantiated, the
Independent Counsel so selected may not serve as Independent Counsel unless and until such objection is withdrawn or a court has determined that such objection is without merit. If, within twenty (20) days after the later of submission by
Indemnitee of a written request for indemnification pursuant to Section 11(a) hereof and the final disposition of the Proceeding, no Independent Counsel shall have been selected and not objected to, either the Company or Indemnitee may petition
a court of competent jurisdiction for resolution of any objection which shall have been made by the Company or Indemnitee to the other’s selection of Independent Counsel and/or for the appointment as Independent Counsel of a person selected by
the Court or by such other person as the Court shall designate, and the person with respect to whom all objections are so resolved or the person so appointed shall act as Independent Counsel under Section 12(a) hereof. Upon the due commencement
of any judicial proceeding or arbitration pursuant to Section 14(a) of this Agreement, Independent Counsel shall be discharged and relieved of any further responsibility in such capacity (subject to the applicable standards of professional
conduct then prevailing). 
 Section 13. Presumptions and Effect of Certain Proceedings. 

(a) In making a determination with respect to entitlement to indemnification hereunder, the person or persons or entity making such
determination shall, to the fullest extent not prohibited by law, presume that Indemnitee is entitled to indemnification under this Agreement if Indemnitee has submitted a request for indemnification in accordance with Section 11(a) of this
Agreement, and the Company shall, to the fullest extent not prohibited by law, have the burden of proof to overcome that presumption in connection with the making by any person, persons or entity of any determination contrary to that presumption.
Neither the failure of the Company (including by its directors or independent legal counsel) to have made a determination prior to the commencement of any action pursuant to this Agreement that indemnification is proper in the circumstances because
Indemnitee has met the applicable standard of conduct, nor an actual determination by the Company (including by its directors or independent legal counsel) that Indemnitee has not met such applicable standard of conduct, shall be a defense to the
action or create a presumption that Indemnitee has not met the applicable standard of conduct. 
 (b) Subject to Section 14(e), if
the person, persons or entity empowered or selected under Section 12 of this Agreement to determine whether Indemnitee is entitled to indemnification shall not have made a determination within sixty (60) days after receipt by the
Company of the request therefor, the requisite determination of entitlement to indemnification shall, to the fullest extent not prohibited by law, be deemed to have been made and Indemnitee shall be entitled to such indemnification, absent
(i) a misstatement by Indemnitee of a material fact, or an omission of a material fact necessary to make Indemnitee’s statement not materially misleading, in connection with the request for indemnification, or (ii) a prohibition of
such indemnification under applicable law; provided, however, that such 60-day period may be extended for a reasonable time, not to exceed an additional thirty (30) days, if the person, persons or entity making the determination with
respect to entitlement to indemnification in good faith requires such additional time for the obtaining or evaluating of documentation and/or information relating thereto; and provided, further, that the foregoing provisions of this
Section 13(b) shall not apply (i) if the determination of entitlement to indemnification is to be made by the stockholders pursuant to Section 12(a) of this Agreement and if (A) within fifteen (15) days after receipt by
the Company of the request for such determination the Board has resolved to submit such determination to the stockholders for their consideration at an annual meeting thereof to be held within seventy-five (75) days after such receipt and
such determination is made thereat, or (B) a special meeting of stockholders is called within fifteen (15) days after such receipt for the purpose of making such determination, such meeting is held for such purpose within
sixty (60) days after having been so called and such determination is made thereat, or (ii) if the determination of entitlement to indemnification is to be made by Independent Counsel pursuant to Section 12(a) of this Agreement.

 (c) The termination of any Proceeding or of any claim, issue or matter therein, by judgment, order, settlement or conviction, or upon
a plea of nolo contendere or its equivalent, shall not (except as otherwise expressly provided in this Agreement) of itself adversely affect the right of Indemnitee to indemnification or create a presumption that Indemnitee did not act
in good faith and in a manner which he reasonably believed to be in or not opposed to the best interests of the Company or, with respect to any criminal Proceeding, that Indemnitee had reasonable cause to believe that his conduct was unlawful. 

 (d) Reliance as Safe Harbor. For purposes of any determination of good faith,
Indemnitee shall be deemed to have acted in good faith if Indemnitee’s action is based on the records or books of account of the Enterprise, including financial statements, or on information supplied to Indemnitee by the officers of the
Enterprise in the course of their duties, or on the advice of legal counsel for the Enterprise or on information or records given or reports made to the Enterprise by an independent certified public accountant or by an appraiser or other expert
selected with the reasonable care by the Enterprise. The provisions of this Section 13(d) shall not be deemed to be exclusive or to limit in any way the other circumstances in which the Indemnitee may be deemed to have met the applicable
standard of conduct set forth in this Agreement. 
 (e) Actions of Others. The knowledge and/or actions, or failure to act, of
any director, officer, agent or employee of the Enterprise shall not be imputed to Indemnitee for purposes of determining the right to indemnification under this Agreement. 

Section 14. Remedies of Indemnitee. 

(a) Subject to Section 14(e), in the event that (i) a determination is made pursuant to Section 12 of this Agreement that
Indemnitee is not entitled to indemnification under this Agreement, (ii) advancement of Expenses is not timely made pursuant to Section 10 of this Agreement, (iii) no determination of entitlement to indemnification shall have been
made pursuant to Section 12(a) of this Agreement within ninety (90) days after receipt by the Company of the request for indemnification, (iv) payment of indemnification is not made pursuant to Section 5, 6 or 7 or the last
sentence of Section 12(a) of this Agreement within ten (10) days after receipt by the Company of a written request therefor, (v) payment of indemnification pursuant to Section 3, 4 or 8 of this Agreement is not made within
ten (10) days after a determination has been made that Indemnitee is entitled to indemnification, or (vi) in the event that the Company or any other person takes or threatens to take any action to declare this Agreement void or
unenforceable, or institutes any litigation or other action or Proceeding designed to deny, or to recover from, the Indemnitee the benefits provided or intended to be provided to the Indemnitee hereunder, Indemnitee shall be entitled to an
adjudication by a court of his entitlement to such indemnification or advancement of Expenses. Alternatively, Indemnitee, at his option, may seek an award in arbitration to be conducted by a single arbitrator pursuant to the Commercial Arbitration
Rules of the American Arbitration Association. Indemnitee shall commence such proceeding seeking an adjudication or an award in arbitration within 180 days following the date on which Indemnitee first has the right to commence such proceeding
pursuant to this Section 14(a); provided, however, that the foregoing clause shall not apply in respect of a proceeding brought by Indemnitee to enforce his rights under Section 5 of this Agreement. The Company shall not
oppose Indemnitee’s right to seek any such adjudication or award in arbitration. 
 (b) In the event that a determination shall
have been made pursuant to Section 12(a) of this Agreement that Indemnitee is not entitled to indemnification, any judicial proceeding or arbitration commenced pursuant to this Section 14 shall be conducted in all respects as a de
novo trial, or arbitration, on the merits and Indemnitee shall not be prejudiced by reason of that adverse determination. In any judicial proceeding or arbitration commenced pursuant to this Section 14 the Company shall have the burden
of proving Indemnitee is not entitled to indemnification or advancement of Expenses, as the case may be. 
 (c) If a determination shall
have been made pursuant to Section 12(a) of this Agreement that Indemnitee is entitled to indemnification, the Company shall be bound by such determination in any judicial proceeding or arbitration commenced pursuant to this Section 14,
absent (i) a misstatement by Indemnitee of a material fact, or an omission of a material fact necessary to make Indemnitee’s statement not materially misleading, in connection with the request for indemnification, or (ii) a
prohibition of such indemnification under applicable law. 
 (d) The Company shall, to the fullest extent not prohibited by law, be
precluded from asserting in any judicial proceeding or arbitration commenced pursuant to this Section 14 that the procedures and presumptions of this Agreement are not valid, binding and enforceable and shall stipulate in any such court or
before any such arbitrator that the Company is bound by all the provisions of this Agreement. It is the intent of the Company that, to the fullest extent permitted by law, the Indemnitee not be required to incur legal fees or other Expenses
associated with the interpretation, enforcement or defense of Indemnitee’s rights under this Agreement by litigation or otherwise because the cost and expense thereof would substantially detract from the benefits intended to be extended to the
Indemnitee hereunder. The Company shall, to the fullest extent permitted by law, indemnify Indemnitee against any and all Expenses and, if requested by Indemnitee, shall (within ten (10) days after receipt by the Company of a written
request therefor) advance, to the extent not prohibited by law, such Expenses to Indemnitee, which are incurred by Indemnitee in connection with any action brought by Indemnitee for indemnification or advancement of Expenses from the Company under
this Agreement or under any directors’ and officers’ liability insurance policies maintained by the Company if Indemnitee is wholly successful on the underlying claims; if Indemnitee is not wholly successful on the underlying claims, then
such indemnification and advancement shall be only to the extent Indemnitee is successful on such underlying claims or otherwise as permitted by law, whichever is greater. 

 (e) Notwithstanding anything in this Agreement to the contrary, no determination as to
entitlement of Indemnitee to indemnification under this Agreement shall be required to be made prior to the final disposition of the Proceeding. 

Section 15. Non-exclusivity; Survival of Rights; Insurance; Subrogation. 

(a) The rights of indemnification and to receive advancement of Expenses as provided by this Agreement shall not be deemed exclusive of
any other rights to which Indemnitee may at any time be entitled under applicable law, the Certificate of Incorporation, the Bylaws, any agreement, a vote of stockholders or a resolution of directors, or otherwise. No amendment, alteration or repeal
of this Agreement or of any provision hereof shall limit or restrict any right of Indemnitee under this Agreement in respect of any action taken or omitted by such Indemnitee in his Corporate Status prior to such amendment, alteration or repeal. To
the extent that a change in Delaware law, whether by statute or judicial decision, permits greater indemnification or advancement of Expenses than would be afforded currently under the Bylaws, the Certificate of Incorporation and this Agreement, it
is the intent of the parties hereto that Indemnitee shall enjoy by this Agreement the greater benefits so afforded by such change. No right or remedy herein conferred is intended to be exclusive of any other right or remedy, and every other right
and remedy shall be cumulative and in addition to every other right and remedy given hereunder or now or hereafter existing at law or in equity or otherwise. The assertion or employment of any right or remedy hereunder, or otherwise, shall not
prevent the concurrent assertion or employment of any other right or remedy. 
 (b) To the extent that the Company maintains an
insurance policy or policies providing liability insurance for directors, officers, employees, or agents of the Company or of any other corporation, partnership, joint venture, trust, employee benefit plan or other enterprise which such person
serves at the request of the Company, Indemnitee shall be covered by such policy or policies in accordance with its or their terms to the maximum extent of the coverage available for any such director, officer, employee or agent under such policy or
policies. If, at the time of the receipt of a notice of a claim pursuant to the terms hereof, the Company has director and officer liability insurance in effect, the Company shall give prompt notice of such claim or of the commencement of a
proceeding, as the case may be, to the insurers in accordance with the procedures set forth in the respective policies. The Company shall thereafter take all necessary or desirable action to cause such insurers to pay, on behalf of the Indemnitee,
all amounts payable as a result of such proceeding in accordance with the terms of such policies. 
 (c) In the event of any payment
under this Agreement, the Company shall be subrogated to the extent of such payment to all of the rights of recovery of Indemnitee, who shall execute all papers required and take all action necessary to secure such rights, including execution of
such documents as are necessary to enable the Company to bring suit to enforce such rights. 
 (d) The Company shall not be liable under
this Agreement to make any payment of amounts otherwise indemnifiable (or for which advancement is provided hereunder) hereunder if and to the extent that Indemnitee has otherwise actually received such payment under any insurance policy, contract,
agreement or otherwise. 
 (e) The Company’s obligation to indemnify or advance Expenses hereunder to Indemnitee who is or was
serving at the request of the Company as a director, officer, employee or agent of any other corporation, limited liability company, partnership, joint venture, trust, employee benefit plan or other enterprise shall be reduced by any amount
Indemnitee has actually received as indemnification or advancement of Expenses from such other corporation, limited liability company, partnership, joint venture, trust, employee benefit plan or other enterprise. 

Section 16. Duration of Agreement. This Agreement shall continue until and terminate upon the later of:
(a) ten (10) years after the date that Indemnitee shall have ceased to serve as a [director] [officer] [employee] [agent] of the Company or (b) one (1) year after the final termination of any Proceeding then pending in
respect of which Indemnitee is granted rights of indemnification or advancement of Expenses hereunder and of any proceeding commenced by Indemnitee pursuant to Section 14 of this Agreement relating thereto. This Agreement shall be binding upon
the Company and its successors and assigns and shall inure to the benefit of Indemnitee and his heirs, executors and administrators. 

Section 17. Severability. If any provision or provisions of this Agreement shall be held to be invalid, illegal or unenforceable
for any reason whatsoever: (a) the validity, legality and enforceability of the remaining provisions of this Agreement (including without limitation, each portion of any Section of this Agreement containing any such provision held to be
invalid, illegal or unenforceable, that is not itself invalid, illegal or unenforceable) shall not in any way be affected or impaired thereby and shall remain enforceable to the fullest extent permitted by law; (b) such provision or provisions
shall be deemed reformed to the extent necessary to conform to applicable law and to give the maximum effect to the intent of the parties hereto; and (c) to the fullest extent possible, the provisions of this Agreement (including, without
limitation, each portion of any Section of this Agreement containing any such provision held to be invalid, illegal or unenforceable, that is not itself invalid, illegal or unenforceable) shall be construed so as to give effect to the intent
manifested thereby. 

 Section 18. Enforcement. 

(a) The Company expressly confirms and agrees that it has entered into this Agreement and assumed the obligations imposed on it hereby in
order to induce Indemnitee to serve as a director or officer of the Company, and the Company acknowledges that Indemnitee is relying upon this Agreement in serving as a director or officer of the Company. 

(b) This Agreement constitutes the entire agreement between the parties hereto with respect to the subject matter hereof and supersedes
all prior agreements and understandings, oral, written and implied, between the parties hereto with respect to the subject matter hereof; provided, however, that this Agreement is a supplement to and in furtherance of the Certificate of
Incorporation, the Bylaws and applicable law, and shall not be deemed a substitute therefor, nor to diminish or abrogate any rights of Indemnitee thereunder. 

Section 19. Modification and Waiver. No supplement, modification or amendment of this Agreement shall be binding unless executed
in writing by the parties thereto. No waiver of any of the provisions of this Agreement shall be deemed or shall constitute a waiver of any other provisions of this Agreement nor shall any waiver constitute a continuing waiver. 

Section 20. Notice by Indemnitee. Indemnitee agrees promptly to notify the Company in writing upon being served with any summons,
citation, subpoena, complaint, indictment, information or other document relating to any Proceeding or matter which may be subject to indemnification or advancement of Expenses covered hereunder. The failure of Indemnitee to so notify the Company
shall not relieve the Company of any obligation which it may have to the Indemnitee under this Agreement or otherwise. 
 Section 21.
Notices. All notices, requests, demands and other communications under this Agreement shall be in writing and shall be deemed to have been duly given if (a) delivered by hand and receipted for by the party to whom said notice or other
communication shall have been directed, (b) mailed by certified or registered mail with postage prepaid, on the third business day after the date on which it is so mailed, (c) mailed by reputable overnight courier and receipted for by the
party to whom said notice or other communication shall have been directed or (d) sent by facsimile transmission, with receipt of oral confirmation that such transmission has been received: 

(a) If to Indemnitee, at the address indicated on the signature page of this Agreement, or such other address as Indemnitee shall provide
to the Company. 
 (b) If to the Company to 

28 Wells Avenue, Third Floor 

Yonkers, New York 10701 

Attention: Michael Messinger 
 or
to any other address as may have been furnished to Indemnitee by the Company. 
 Section 22. Contribution. To the fullest extent
permissible under applicable law, if the indemnification provided for in this Agreement is unavailable to Indemnitee for any reason whatsoever, the Company, in lieu of indemnifying Indemnitee, shall contribute to the amount incurred by Indemnitee,
whether for judgments, fines, penalties, excise taxes, amounts paid or to be paid in settlement and/or for Expenses, in connection with any claim relating to an indemnifiable event under this Agreement, in such proportion as is deemed fair and
reasonable in light of all of the circumstances of such Proceeding in order to reflect (i) the relative benefits received by the Company and Indemnitee as a result of the event(s) and/or transaction(s) giving cause to such Proceeding; and/or
(ii) the relative fault of the Company (and its directors, officers, employees and agents) and Indemnitee in connection with such event(s) and/or transaction(s). 

Section 23. Applicable Law and Consent to Jurisdiction. This Agreement and the legal relations among the parties shall be governed
by, and construed and enforced in accordance with, the laws of the State of Delaware, without regard to its conflict of laws rules. Except with respect to any arbitration commenced by Indemnitee pursuant to Section 14(a) of this Agreement, the
Company and Indemnitee hereby irrevocably and unconditionally (i) agree that any action or proceeding arising out of or in connection with this Agreement shall be brought only in the Chancery Court of the State of Delaware (the “Delaware
Court”), and not in any other state or federal court in the United States of America or any court in any other country, (ii) consent to submit to the exclusive jurisdiction of the Delaware Court for purposes of any action or proceeding
arising out of or in connection with this Agreement, (iii) appoint, to the extent such party is not otherwise subject to service of process in the State of Delaware, irrevocably The Corporation Service Company, 2711 Centerville Road, Suite 400,
City of Wilmington, County of New Castle, Delaware 19808 as its agent in the State of Delaware as such party’s agent for acceptance of legal process in connection with any such action or proceeding against such party with the same legal force
and validity as if served upon such party personally within the State of Delaware, (iv) waive any objection to the laying of venue of any such action or proceeding in the Delaware Court, and (v) waive, and agree not to plead or to make,
any claim that any such action or proceeding brought in the Delaware Court has been brought in an improper or inconvenient forum. 

 Section 24. Identical Counterparts. This Agreement may be executed in one or more
counterparts, each of which shall for all purposes be deemed to be an original but all of which together shall constitute one and the same Agreement. Only one such counterpart signed by the party against whom enforceability is sought needs to be
produced to evidence the existence of this Agreement. 
 Section 25. Miscellaneous. Use of the masculine pronoun shall be deemed
to include usage of the feminine pronoun where appropriate. The headings of this Agreement are inserted for convenience only and shall not be deemed to constitute part of this Agreement or to affect the construction thereof. 

IN WITNESS WHEREOF, the parties have caused this Agreement to be signed as of the day and year first above written. 

 

									
	CONTRAFECT CORPORATION	  		  	INDEMNITEE
				
	By:	 	  
	  		  	  

	Julia P. Gregory, Chief Executive Officer	  		  	Name:
					
		 		  		  	Address:EX-10.6

 Exhibit 10.6 

EMPLOYMENT AGREEMENT 

THIS EMPLOYMENT AGREEMENT (the “Agreement”) is entered into by and between ContraFect Corporation, a Delaware corporation
(the “Employer”), and Julia P. Gregory, a resident of the State of New York (the “Employee”), as of April 29, 2014. 

WHEREAS, Employer and Employee entered into that certain Employment Agreement (the “Prior Agreement”), dated as of
July 3, 2012, pursuant to which Employee served in the capacity of Employer’s Chief Financial Officer; 
 WHEREAS, subsequent to
the execution of the Prior Agreement, Employee has assumed the position of Chief Executive Officer (“CEO”), though Employer and Employee have not amended the terms of the Prior Agreement to set forth the terms and conditions of
Employee’s service as CEO; and 
 WHEREAS, the Board of Directors of Employer (the “Board”) and Employee desire to
memorialize the terms of Employee’s continued employment as CEO as of Effective Date on the terms set forth herein. 
 NOW, THEREFORE,
in consideration of the mutual agreements set forth below, the parties agree as follows: 
 1.    Employment and
Duties of Employee 
 (a)    Employer hereby employs Employee to serve Employer in the capacity of CEO, reporting to
the Board. Subject to the Board’s direction, as it may change from time to time, Employee shall be responsible for duties commensurate with Employee’s position as CEO. The responsibilities of Employee in Employee’s capacity as CEO may
change depending on the then needs of Employer as determined by the Board in its reasonable discretion. Employee agrees to devote Employee’s full business time, attention, ability, skill and energies to the performance of Employee’s duties
hereunder. 
 (b)    Employee shall comply with all bylaws, policies, procedures, standards and regulations of Employer
now or hereafter promulgated, and which have been provided to Employee in writing, copies of which Employee hereby acknowledges receipt. At Employer’s expense, Employee shall participate in such continuing education as may be required under
applicable ethical or licensing standards, laws, rules and regulations applying to Employee’s profession or as may otherwise be required by Employer. Employee shall obtain and maintain all required licenses, credentials, approvals or other
certifications to perform Employee’s duties and services hereunder. 
 (c)    As of the Effective Date, except as
set forth below, Employee represents that, other than this Agreement, Employee had no, and does not have any, ongoing financial interests or compensation arrangements (“Arrangements”) in any entity or person that develops or sells,
researches, or licenses scientific information or products for the therapy of human diseases (each a “Biotech Venture”). Employee shall not enter into any Arrangements with any Biotech Venture without the prior written consent of
the Board, which consent may be withheld in the reasonable discretion of the Board; provided, however, that Employee is permitted to maintain Employee’s current board activities with Clinipace World Wide and The Global TB Alliance
for Drug Development. Employee is permitted to be on other boards of businesses, civic and not-for –profit organizations so long as such activities do not interfere with the performance of Employee’s duties hereunder. 

 2.    Hours and Place of Employment. Employee and Employer agree that
Employee shall maintain a regular work week as assigned by Employer to similarly situated senior executives of Employer. Employee shall be assigned to work at Employer’s headquarters located in Yonkers, New York, except for usual and customary
travel on Employer’s business. 
 3.    Term of Employment. The term of Employee’s employment under
this Agreement (the “Term”) commenced on April 1, 2014 (the “Effective Date”) and shall last until the first anniversary of the Effective Date, unless terminated earlier in accordance with the terms hereof.
Unless either party elects to terminate this Agreement at the end of the Term or any renewal term by giving the other party notice of such election at least 90 days before the expiration of the Term, this Agreement shall be deemed to have been
renewed for an additional term of one year commencing on the day after the expiration of the then-current term and so on from year to year. 

4.    Termination. 

(a)    Either party shall have the right to terminate Employee’s employment under this Agreement at any time for any
reason or no reason upon 30 days’ prior written notice. In the event that Employer or Employee gives notice to terminate pursuant to the foregoing sentence, Employer may elect to have Employee cease working immediately so long as Employer
continues to pay Employee’s Base Salary in accordance with the provisions of this Section (4)(a) for the entire 30 day notice period. In the event Employer elects to have Employee immediately cease working during the 30 day notice period
as provided in the foregoing sentence and Employee finds alternative employment that is not in violation of any provision herein, including, without limitation, Sections 10 and 11 hereof, Employee may accept and engage in the alternative
employment. 
 (b)    In the event that, during the Term, (i) Employee is terminated by Employer without Cause (as
defined below) or (ii) Employee resigns for Good Reason (as defined below) (each a “Qualifying Termination”), then Employee shall be entitled to receive severance benefits commencing on the day after Employee’s last day of
employment. Such benefits will include: (1) 18 months of severance at the Applicable Rate (as defined below), payable in accordance with Employer’s payroll practices in effect from time to time; (2) deemed vesting as to 100% of
any such unvested portion of both the Initial Option Grant (as defined below) and the option granted on February 27, 2013 that would have vested in the 18-month period following the date of such termination, with such vesting occurring as of
the date of Employee’s termination of employment; (3) accelerated vesting of such portion of the CEO Option Grant that would have vested through March 31st of the year following the
year in which termination occurs; and (4) applicable premiums (inclusive of premiums for Employee’s dependents) pursuant to COBRA for 12 months from the date of termination for the health insurance (and dental and vision insurance if then
in force and subject to COBRA) plan sponsored by the Company, all the foregoing provided that Employee executes and does not revoke a release of claims in a form prescribed by Employer, which release shall become effective no later than the 60th day following Employee’s termination of employment, provided that if the execution of the release spans two taxable years, no severance payments shall be made until the beginning of the
second taxable year. Severance payments shall be made over a period of 18 months from the date of Employee’s termination of employment, unless specified otherwise. In no event shall any severance payments become payable until the first payroll
period after the release of claims required pursuant to this Section 4(b) becomes effective, with payments otherwise to have been made prior to the effectiveness of the release to be paid on the first payroll period following effectiveness. For
purposes of this Section 4(b) only, the term “Applicable Rate” shall mean (x) in the event that Employer elects to renew the Agreement after the first anniversary of the Effective Date, then for any Qualifying Termination
that occurs on or following April 1, 2015, salary continuation at the Base Salary for the entire 18-month salary continuation period, plus an amount up to 50% of Base Salary for the Target Bonus, all payable over the 18-month severance period or (y) for any Qualifying Termination that occurs prior to the first anniversary of the Effective Date, salary continuation at the Base Salary for the period beginning on the date of
termination and continuing through March 31, 2015, and at the Reduced Salary for the period beginning on April 1, 2015 and continuing through the balance of the of the 18-month salary continuation period, plus an amount equal to, as
applicable, either (I) up to 50% of Base Salary for the Target Bonus (the actual amount of the Target Bonus to be reasonably determined by the Compensation Committee of the Board based on Employee’s contributions to the Company, and her
length of service, during the termination year) or (II) solely in the case of Qualifying Termination as a result of a resignation for Good Reason pursuant to the event described in Section 4(c)(ii) below occurring prior to April 1, 2015,
an amount no less than 25% of the Reduced Salary, all payable over the 18-month severance period. 

  
 2 

 (c)    Good Reason shall mean the occurrence of any of the events or
circumstances described in the following subsections (i) through (vi) that occur during the Term without Employee’s consent: 

(i)    a diminution in Employee’s title as CEO or requiring Employee to perform on a regular basis
duties materially inconsistent with Employee’s position as CEO; 
 (ii)    an election by Employer
not to renew the Agreement at the end of the Term or any subsequent extension thereof; 
 (iii)    a
material reduction in Employee’s Base Salary; 
 (iv)    any material breach by Employer or any of
its successors and assigns of this Agreement that is not cured within 30 days Employee provides Employer with written notice of the facts comprising the alleged material breach; 

(v)    the failure of Employer’s successors and/or assigns to assume the obligations of Employer
under this Agreement, either by written agreement or by operation of law; or 

  
 3 

 (vi)    the relocation of Employee’s principal place of
employment to a location that is more than 50 miles “as the crow flies” from Employee’s place of employment as of the Effective Date. 

Employee must provide written notice (“Notice of Good Reason”) to Employer of the existence of a condition described in subsections
(i) through (vi) above within 30 days of Employee’s knowledge of the initial existence of the condition or such right is waived. The Notice of Good Reason shall fully set forth the facts comprising the event(s) or circumstance(s)
giving rise to Good Reason. Employer shall have a period (the “Good Reason Notice Period”) of 30 days during which it may remedy the condition so that it shall not constitute Good Reason or inform Employee that is does not believe
Good Reason exists. If Employee believes that the condition has not been cured, or that Good Reason exists notwithstanding Employer’s belief that it does not, then Employee shall either abandon the contention that Good Reason exists or
terminate employment within 30 days. If Employee continues to work beyond the 30th day without resigning, Employee shall be deemed to have waived Good Reason for the event(s) or circumstance(s)
set forth in the Notice of Good Reason. 
 5.    Compensation of Employee. 

(a)    Base Salary. As compensation for the services to be performed by Employee during the Term, Employer agrees
to pay Employee a base salary of $475,000 per annum (the “Base Salary”), which Base Salary shall be retroactive to January 1, 2014. All such payments shall be prorated for any partial month or year and shall be payable in
accordance with Employer’s customary payroll practices in effect from time to time. Employer will review Employee’s performance annually and discuss the review with Employee. Employee’s Base Salary may subsequently be increased, but
not decreased, as a result of such performance review. For purposes of Section 4(b) only, the term “Reduced Salary” shall mean an amount equal to $424,000 per annum. 

(b)    Annual Bonus Opportunity. For each calendar year during the Term, Employee shall be eligible to receive a
bonus (the “Target Bonus”) up to a maximum amount of 50% of Base Salary for performance at the maximum level; provided, however, that Employee must be employed as CEO as of December 31st of the year to which the Target Bonus relates in order to be paid the Target Bonus. The calculation of the Target Bonus shall be based upon corporate performance factors established and assessed by
the Board or a committee thereof that will take into account the performance of Employer’s business as a whole. The Target Bonus shall be paid in a lump sum cash payment as soon as reasonably practicable following December 31st of the year to which the Target Bonus relates; provided, however, that the Target Bonus will be paid no later than March 15th
of the year following the year to which the Target Bonus relates. 

  
 4 

 (c)    CEO Option Grant. As soon as reasonably practicable following
the execution of this Agreement, the Board or a committee thereof intends to approve a grant of stock options (the “CEO Option Grant”) covering 2,400,000 option shares. The CEO Option Grant shall be pursuant to the Employer’s
Amended & Restated 2008 Equity Incentive Plan. Employer shall deliver an award agreement to Employee that sets forth the terms and conditions of the CEO Option Grant (the “CEO Award Agreement”). The CEO Award Agreement
shall provide that the option shares subject to the CEO Option Grant shall vest in equal quarterly installments while Employee serves as CEO hereunder over a period of three years, which vesting shall commence on the Effective Date. If Employee
ceases to serve as CEO, but remains employed by Employer in another capacity, Employee shall forfeit any unvested portion of the CEO Option Grant (after giving effect to any pro rata vesting of the portion of the CEO Option Grant that would have
become vested at the end of the then-current quarter based on the number of days that Employee served as CEO in the calendar quarter in which Employee ceases to serve as CEO), and the vested portion of the CEO Option Grant shall remain outstanding
and exercisable by Employee during continued employment with Employer and for such post-employment exercise period as is specified in the CEO Award Agreement. In the event that Employee’s employment is terminated during the Term, Employee shall
forfeit any unvested portion of the CEO Option Grant (after giving effect to any accelerated vesting resulting from a Qualified Termination), and any vested portion of the CEO Option Grant shall remain exercisable by Employee for the post-employment
exercise period specified in the CEO Award Agreement. 
 (d)    Initial Option Grant. In connection with the
execution of the Prior Agreement, Employer granted Employee 470,000 stock options to purchase shares of Employer’s common stock (the “Initial Grant”), which was memorialized in that certain Stock Option Agreement dated as of
August 11, 2012 (the “Initial Award Agreement”). This Agreement is not intended to, nor does it, in any way alter or amend the terms of the Initial Grant as set forth in the Initial Award Agreement. 

(e)    Corporate Bonus. During the 2014 calendar year only, Employee shall be eligible to receive a bonus based on
capital raised or third-party investments secured by Employer during the 2014 calendar year (the “Corporate Bonus”). The Corporate Bonus shall be calculated as follows. 

(i)    Part B – should Employer raise cash or investments in the aggregate totaling $20 million
during calendar year 2014, Employee shall receive $100,000 with which Employee may purchase shares of fully-vested common stock. 
 The Corporate
Bonus, if any, shall be paid as soon as reasonably practicable following December 31, 2014; provided, however, that the Corporate Bonus shall be paid no later than March 15, 2015. Employer acknowledges and agrees that
Employee is entitled to, and will be paid, a $50,000 cash bonus in respect of capital raised by Employer during calendar year 2013. 

(f)    Employee shall be entitled to participate in such fringe benefit programs as Employer may offer to its senior
employees generally, including payment of health insurance premiums for Employee, Employee’s spouse and Employee’s eligible dependents. Employer’s current health insurance plan is with Oxford and also includes optical and
dental coverage. Employer reserves the right, subject to decisions of its Board of Directors, to amend, decrease or discontinue any benefit program at any time without advance notice to or consent of Employee, consistent with the manner in which
Employer changes the benefit programs for other similarly situated senior executives of Employer. 

  
 5 

 6.    Absences and Vacation. In each calendar year of Employee’s
employment Employee shall have off as paid vacation the Christmas/New Year’s break starting with December 24 as the first day off and ending on January 1 of the following year (the “Winter Vacation”). In addition, in
each calendar year of Employee’s employment Employee shall be entitled to 14 days paid vacation on dates that are subject to the approval of Employer and are not within one month of the Winter Vacation. Employee shall be entitled to five paid
sick days and two personal days in each year of Employee’s employment. Except as to sick days, vacation time off shall be taken at a time reasonably convenient to Employer. In the event Employee’s employment terminates prior to the end of
the term hereof, such entitlement shall be prorated. Any unused time off at the end of any calendar year of this Agreement shall not entitle Employee to payment therefor and may not be carried forward into any subsequent period of employment. All
vacation and sick time shall be prorated if Employee’s employment shall start or end during a calendar year. 

7.    Expenses. Employer agrees to reimburse Employee for approved expenses reasonably incurred during the course
of Employee’s employment. Such reimbursement shall be made upon presentation of receipts satisfactory to Employer for expenses actually incurred in connection with the foregoing. 

8.    Termination Other Than For Cause. 

(a)    In the event of Employee’s death, Employee’s employment shall terminate immediately and Employee’s
estate shall be paid Employee’s accrued Base Salary and accrued 2014 Bonus or Target Bonus (as applicable), if any, through the date on which such death occurred. 

(b)    If Employee after working for six months for Employer becomes unable to perform the essential functions of
Employee’s duties (with reasonable accommodation, if requested) due to partial or total disability or incapacity resulting from a mental or physical illness or injury or any similar cause, Employer will continue the payment of Employee’s
Base Salary for a period of three months, or until Employee is able to return to work, whichever is shorter, provided, however, that Employee shall first be required to use any accrued and unused vacation time, sick time and personal
days before Employer’s obligation to begin Base Salary continuation commences. Following the end of the Base Salary continuation provided for in this Section 8(b), Employer shall have no obligation to continue to pay Employee’s Base
Salary to Employee during the continuance of such disability or incapacity. Any disability payments that are paid to Employee from Employer provided disability insurance shall be applied as an offset against Employer’s Base Salary continuation
under this subsection 8(b). Notwithstanding anything to the contrary contained herein, Employee shall not be entitled to receive Base Salary pursuant to this subsection 8(b) for more than three months in any consecutive 12 month period. At such time
as the Family and Medical Leave Act shall apply to Employer, if ever, Employee shall have such rights as are provided for thereunder. 

9.    Termination for Cause. 

(a)    Employee’s employment under this Agreement shall be deemed to be terminated upon the occurrence of any of the
following events that shall constitute Cause, immediately upon Employer giving written notice of such termination to Employee: 

  
 6 

 (i)    Employee’s conviction of, or plea of no contest
to, any felony or a crime involving moral turpitude; 
 (ii)    Employee’s repeated failure or
refusal to follow, in any material respect, the instructions of Employer, the Board or the bylaws, policies, standards or regulations of or applicable to Employer that have been provided to Employee in writing, which from time to time may be
established or changed; 
 (iii)    Employee’s continued failure or refusal to faithfully and
diligently perform, in any material respect, the usual and customary duties of Employee’s employment hereunder; or 

(iv)    Employee’s conduct is fraudulent, or Employee willfully disregards lawful instructions of the
Board, which is not cured within 30 days after being given written notice of the facts. 
 No termination for Cause may occur unless Employer delivers a
written notice to Employee setting forth the conduct allegedly constituting Cause within 30 days of Employer’s knowledge of the initial existence of the condition of the event(s) or circumstance(s) constituting Cause and specifying the
particulars thereof in reasonable detail, and Employee has been provided an opportunity to be heard in person by the Board. 

10.    Proprietary and Confidential Information. 

(a)    Confidential Information. Employee acknowledges that, during the course of Employee’s service with
Employer, Employee will have access to Confidential Information (as defined below) and materials not generally known outside Employer. For all purposes of this Agreement, “Confidential Information” means all information and
materials (whether conceived or developed by Employee or others), marketing and other business plans, customers and customer information, data strategies, research, reports, copyrights and patents related to Employer. During the Term, Employee shall
not, without the prior written consent of Employer, communicate or divulge any Confidential Information or materials to anyone other than Employer and its partners, affiliates, employees, consultants and those designated by it, except in the course
of carrying out Employee’s duties or as required by law. Employee acknowledges that Confidential Information is and shall remain the property of Employer. The confidentiality obligations hereunder shall not apply to Confidential Information
which: (i) is, or later becomes, public knowledge other than by Employee’s breach of this Agreement; (ii) is in the possession of Employee with the full right to disclose same prior to Employee’s receipt of it from Employer; or
(iii) is independently received by Employee from a third party, with no restrictions of disclosure. Furthermore, Employee agrees not to use Confidential Information for any purposes other than to perform duties for Employer hereunder. Employee
shall also execute Employer’s standard Confidentiality Agreement in the form set forth in Exhibit 10(a) and thereafter in such form as Employer may present to Employee. 

  
 7 

 (b)    Ownership of Patents and Intellectual Property. Employee agrees
that any work prepared for Employer during the course of Employee’s employment by Employer that is eligible for copyright and patent protection under the laws of the United States or any other country and any proprietary know-how developed by
Employee while rendering services for Employer, will vest in Employer. Employee hereby grants, transfers and assigns all right, title and interest in such work and all copyrights and patents in such work and all renewals and extensions thereof to
Employer, and agrees to provide all assistance reasonably requested by Employer in the establishment, preservation and enforcement of Employer’s copyright and patents in such work, such assistance to be provided at Employer’s expense but
without any additional compensation to Employee if Employee is employed by Employer at the time such assistance is requested and for reasonable compensation and subject to Employee’s reasonable availability if such assistance is requested
following Employee’s termination of employment. If Employer cannot, after reasonable effort, secure Employee’s signature on any documents needed to apply for or prosecute any patent, copyright or other right or protection relating to an
invention, whether because of Employee’s physical or mental incapacity or for any other reason whatsoever, Employee hereby irrevocably designates and appoints Employer and its duly authorized officers and agents as Employee’s agent and
attorney-in-fact, to act for and on Employee’s behalf and in Employee’s name and stead for the purpose of executing and filing any such application or applications and taking all other lawfully permitted actions to further the prosecution
and issuance of patents, copyrights, or similar protections thereon, with the same legal force and effect as if executed by Employee. 

(c)    Litigation. Employee agrees to render assistance to and cooperate with Employer at its request regarding any
matter, dispute or controversy with which Employer may become involved and of which Employee has useful knowledge, information or expertise. Such assistance shall be provided at Employer’s expense but without any additional compensation to
Employee if Employee is employed by Employer at the time such assistance is requested, and for reasonable compensation and subject to Employee’s reasonable availability if such assistance is requested following Employee’s termination of
employment. Following termination of Employee’s employment, Employee shall not be required to cooperate other than as a fact witness. Employer agrees to pay all expenses reasonably incurred or to be incurred by Employee in connection with any
cooperation requested by Employer. 
 11.    Covenants not to Compete. 

(a)    Non-competition. Employee acknowledges that Employee’s duties hereunder and the services Employee will
provide to Employer are of a special, unique, unusual and extraordinary character, which gives this Agreement particular value to Employer, and that the knowledge Employee will learn while working for Employer is such that it will necessarily be
valuable to a competitor and almost impossible to keep confidential if Employee were to work for a competitor. Therefore, during the Term and for a period of one year after Employee’s termination of employment for any reason (such period, the
“Restricted Period”), Employee will not, directly or indirectly, enter into, organize, control, engage in, be employed by, serve as a consultant to, be an officer or director of, or have any direct investment of more than 5% of the
outstanding shares in, any business, person, partnership, association, firm, corporation, or other entity engaged in any business activity (including, but not limited to, research, development, manufacturing, selling, leasing, licensing or providing
services) which is competitive with the business of Employer. For purposes of this Agreement, a business activity is competitive with the business of Employer if it is being done on behalf of any business, person, partnership, association, firm,
corporation, or other entity that owns, develops, sells, researches, or licenses scientific information or products involving antibodies, lysins and other bacterial products specifically for the treatment of human pathogens. This does not preclude
Employee working for a diversified biotech company that discovers and develops therapies to address multiple therapeutic areas (including, without limitation, oncology, inflammation, metabolic disease or neurology in addition to infectious disease),
as long as Employee does not directly or indirectly engage in work and projects aimed at addressing infectious disease in ways that would directly compete with Employer during the Restricted Period. 

  
 8 

 (b)    Non-diversion. During the Restricted Period, Employee will not
divert or attempt to divert or take advantage of or attempt to take advantage of any actual or potential business or opportunities of Employer. 

(c)    Non-recruitment. Employee acknowledges that Employer has and will continue to invest substantial time and
effort in assembling its workforce. Accordingly, Employee agrees that, during the Restricted Period, Employee will not directly or indirectly (i) hire away any individuals who were employed by, or providing independent contractor services to,
Employer during the one-year period prior to the date of termination of Employee’s service with Employer, or (ii) directly or indirectly, entice, solicit or seek to induce or influence any such employees or independent contractors to leave
or curtail their service with Employer or to provide services to others. In addition, during the Restricted Period, Employee agrees that Employee will not directly or indirectly solicit any customer of Employer for the benefit of Employee or any
other business venture. 
 12.    Remedies. 

(a)    Employee acknowledges and agrees that the restrictions contained in Sections 10 and 11, in view of the nature of
the business of Employer, are reasonable and necessary in order to protect the legitimate interests of Employer. Employee acknowledges that any violation of such restrictions are likely to result in irreparable injuries to Employer, and Employee
therefore acknowledges that, in the event of Employee’s violation of any of these restrictions, Employer shall be entitled to seek from any court of competent jurisdiction preliminary and permanent injunctive relief without proving actual
damage or immediate or irreparable harm and without posting any bond. In addition, Employer shall be entitled to seek damages and an equitable accounting of all earnings, profits and other benefits received by Employee arising from such violation,
which rights shall be cumulative and in addition to any other rights or remedies to which Employer may be entitled. 

(b)    If the time, geographic, or other limitations specified in Sections 10 and 11 above should be adjudged to exceed
limitations permitted by applicable law in any proceeding, then the affected provisions shall be deemed reformed in such jurisdiction to the maximum time, geographic, product or service or other limitations permitted by applicable law. If Employee
violates any of the restrictions contained in the foregoing Sections 10 and 11, the Restricted Period shall be tolled during the time of any such breach. 

(c)    In view of the difficulty of determining the amount of damages that may result to the parties hereto from the
breach of the provision of Section 10 or 11, it is the intent of the parties hereto that, in addition to monetary damages, any non-breaching party shall have the right to prevent any such breach in equity or otherwise, including without
limitation prevention by means of injunctive relief. The prevailing party in any such action shall be entitled to an award of its reasonable attorney’s fees and costs. 

  
 9 

 13.    Publicity. If Employee is terminated without Cause, Employer
and Employee will agree on oral and written statements to be released publicly regarding Employee’s departure. 

14.    Non-disparagement. Employee and Employer mutually agree that, during Term and for a period of five years
thereafter, neither will directly or indirectly disparage the other. 
 15.    Entire Agreement; Amendments. This
Agreement and its attachments constitutes the entire agreement and understanding between Employer and Employee relating to the subject matter hereof, and shall not be amended or changed except by written instrument signed by each of the undersigned
parties. There are no prior or contemporaneous oral or written understandings or agreements between the parties regarding Employee’s employment by Employer or any other matter. 

16.    No Waiver. Neither Employee nor Employer shall by any act, delay, indulgence, omission or otherwise be
deemed to have waived any right or remedy hereunder or to have acquiesced in any default in or breach of any of the terms and conditions hereof. No failure to exercise, nor any delay in exercising, on the part of Employee or Employer, any right,
power or privilege hereunder shall operate as a waiver thereof. No single or partial exercise of any right, power or privilege hereunder shall preclude any other or further exercise thereof or the exercise of any other right, power or privilege.

 17.    Waiver of Jury Trial. The parties hereto waive any and all rights to a trial by jury with respect to
any action arising hereunder. 
 18.    Governing Law, Venue, Interpretation of Language. The parties agree that
this Agreement shall be governed by the laws of the State of New York, without regard to conflict of laws principles, and that venue for any action between the parties that arises out of this Agreement shall be in New York County, State of New York.
In the event an ambiguity or question of intent or interpretation arises, this Agreement shall be construed as if drafted jointly by the parties and no presumption or burden of proof shall arise favoring or disfavoring any party by virtue of the
authorship of any of the provisions of this Agreement. 
 19.    Resignation as Officer and Director. In the
event that Employee’s employment with Employer is terminated for any reason whatsoever, Employee agrees to immediately resign from any position Employee may hold as an officer or director of, or on behalf of, Employer. 

20.    Notices. Any notices under this Agreement shall be given in writing in person or by registered or certified
U.S. mail, postage prepaid, return receipt requested, or by facsimile with confirmation, to the parties at their respective addresses set forth below, and such notices shall be deemed given when received or three days after placed in the mail in the
manner provided above. Either party may change such party’s address for notice by giving notice as provided herein. 

  
 10 

 If to Employer: 

ContraFect Corporation 
 28 Wells
Avenue, Third Floor 
 Yonkers, NY 10701 

ATTN: General Counsel 
 With a
copy (which shall not constitute notice) to: 
 John J. Cannon, III 

Shearman & Sterling LLP 

599 Lexington Avenue 
 New York,
NY 10022 
 If to Employee: 

At the last known address in Employer’s files 

21.    Prior Agreements. Employee represents to Employer that (a) there are no restrictions, agreements or
understandings to which Employee is a party that would prevent or make unlawful Employee’s execution of this Agreement or Employee’s continued employment hereunder, (b) Employee’s execution of this Agreement and Employee’s
employment hereunder shall not constitute a breach of any contract, agreement or understanding, oral or written, to which Employee is a party or by which Employee is bound, (c) Employee is free and able to execute this Agreement and to enter
into employment by Employer, and (d) Employee shall not divulge to Employer any trade secrets or proprietary information that belongs to any other person or entity. 

22.    No Assignment. This Agreement and the rights and obligations of both parties hereunder are personal in
nature, and shall not be assignable by either party hereto, except by operation of law. Notwithstanding the foregoing, Employer shall be required to assign all of its rights hereunder to a successor in interest. 

23.    Headings. Headings used in this Agreement are solely for the convenience of the parties and shall be given
no effect in the construction or interpretation of this Agreement. 
 24.    Compliance with Section 409A.
The parties intend that any compensation, benefits and other amounts payable or provided to Employee under this Agreement be paid or provided in compliance with Section 409A of the Internal Revenue Code and all regulations, guidance, and other
interpretative authority issued thereunder (collectively, “Section 409A”) such that there will be no adverse tax consequences, interest, or penalties for Employee under Section 409A as a result of the payments and benefits paid
or provided to Employee. The parties agree to modify this Agreement, or the timing (but not the amount) of the payment of severance or other compensation, or both, to the extent necessary and permissible to comply with Section 409A. In
addition, notwithstanding anything to the contrary contained in any other provision of this Agreement, the payments and benefits provided to Employee under this Agreement shall be subject to the provisions set forth below: 

  
 11 

 (a)    The date of Employee’s “separation from service,” as
defined in the regulations issued under Section 409A, shall be treated as Employee’s date of termination for purposes of determining the time of payment of any amount that becomes payable to Employee pursuant to Section 3 hereof upon
the termination of Employee’s employment and that is treated as an amount of deferred compensation for purposes of Section 409A. 

(b)    In the case of any amounts that are payable to Employee under this Agreement, or under any other “nonqualified
deferred compensation plan” (within the meaning of Section 409A) maintained by Employer in the form of installment payments, Employee’s right to receive such payments shall be treated as a right to receive a series of separate
payments under Treas. Reg. §1.409A-2(b)(2)(iii). 
 (c)    If Employee is a “specified employee” within
the meaning of Section 409A at the time of Employee’s “separation from service” within the meaning of Section 409A, then any payment otherwise required to be made to Employee under this Agreement on account of
Employee’s separation from service, to the extent such payment (after taking in to account all exclusions applicable to such payment under Section 409A) is properly treated as deferred compensation subject to Section 409A, shall not
be made until the first business day after (i) the date that is six months from the date of Employee’s separation from service, or (ii) if earlier, the date of Employee’s death (the “Delayed Payment Date”). On
the Delayed Payment Date, there shall be paid to Employee or to Employee’s estate, in a single cash lump sum, an amount equal to aggregate amount of the payments delayed pursuant to the preceding sentence. 

(d)    To the extent that the reimbursement of any expenses or the provision of any in-kind benefits pursuant to
this Agreement is subject to Section 409A, (i) the amount of such expenses eligible for reimbursement, or in-kind benefits to be provided hereunder during any one calendar year shall not affect the amount of such expenses eligible for
reimbursement or in-kind benefits to be provided hereunder in any other calendar year; provided, however, that the foregoing shall not apply to any limit on the amount of any expenses incurred by Employee that may be reimbursed or paid
under the terms of Employer’s medical plan, if such limit is imposed on all similarly situated participants in such plan; (ii) all such expenses eligible for reimbursement hereunder shall be paid to Employee as soon as administratively
practicable after any documentation required for reimbursement for such expenses has been submitted, but in any event by no later than December 31 of the calendar year following the calendar year in which such expenses were incurred; and
(iii) Employee’s right to receive any such reimbursements or in-kind benefits shall not be subject to liquidation or exchange for any other benefit. 

25.    Withholding. Employer shall have the right to withhold from any amount payable hereunder any Federal, state
and local taxes in order for Employer to satisfy any tax and other lawful withholding obligations it may have under any applicable law or regulation. 

26.    Entire Agreement. This Agreement contains the entire agreement between Employer and Employee with respect to
Employer’s employment of Employee and, except as expressly provided for in this Agreement, supersedes and nullifies all previous agreements between the parties hereto regarding Employer’s employment of Employee. 

  
 12 

 27.    Miscellaneous. 

(a)    Counterparts. This Agreement may be executed in any number of counterparts, each of which shall be deemed to
be an original as against any party whose signature appears thereon, and all of which shall together constitute one and the same instrument. This Agreement shall become binding when one or more counterparts hereof, individually or taken together,
shall bear the signatures of all of the parties reflected hereon as the signatories. 
 (b)    Provisions
Separable. The provisions of this Agreement are independent of and separable from each other, and no provision shall be affected or rendered invalid or unenforceable by virtue of the fact that for any reason any other or others of them may be
invalid or unenforceable in whole or in part. 
 (c)    Survival. Upon the expiration or other termination of
this Agreement, the respective rights and obligations of the parties hereto shall survive such expiration or other termination to the extent necessary to carry out the intentions of the parties under this Agreement. 

[END OF TEXT. SIGNATURE PAGE FOLLOWS.] 

  
 13 

 IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be signed and delivered as
of the date first written above. 

			
	EMPLOYER:
		
	By:	 	 
	Name:	 	
	Title:	 	

  
  

			
	EMPLOYEE:
		
	By:	 	 
		 	Julia P. Gregory

  
 [Signature Page to Employment
Agreement]

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00232-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00232-of-00352.parquet"}]]