Document:

Warrant to Purchase Series F Preferred Stock dated December 19, 2003.

 Exhibit 10.19 
  
 THE SECURITIES REPRESENTED BY THIS WARRANT HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AND HAVE BEEN ACQUIRED FOR INVESTMENT
AND NOT WITH A VIEW TO, OR IN CONNECTION WITH, THE SALE OR DISTRIBUTION THEREOF. NO SUCH SALE OR DISTRIBUTION MAY BE EFFECTED WITHOUT AN EFFECTIVE REGISTRATION STATEMENT RELATED THERETO OR AN OPINION OF COUNSEL IN A FORM SATISFACTORY TO THE COMPANY
THAT SUCH REGISTRATION IS NOT REQUIRED UNDER THE SECURITIES ACT OF 1933. 

  

	 Warrant No. WPF-5 
	 Number of Shares: 4,208 

	 Date of Issuance: December 19, 2003 
	 (subject to adjustment) 

  
 XCYTE THERAPIES, INC. 
  
 Series F Preferred Stock Purchase Warrant 
  
 Xcyte Therapies, Inc., a Delaware corporation (the “Company”), for value received, hereby certifies that Oxford Finance Corporation, or its
registered assigns (the “Registered Holder”), is entitled, subject to the terms set forth below, to purchase from the Company, at any time after the date hereof and on or before the Expiration Date (as defined in Section 7 below), up to
4,208 shares of Series F Preferred Stock of the Company (“Preferred Stock”), at a purchase price of $2.78 per share. The shares purchasable upon exercise of this Warrant and the purchase price per share, as adjusted from time to time
pursuant to the provisions of this Warrant, are hereinafter referred to as the “Warrant Stock” and the “Purchase Price,” respectively. 
  
 1. Exercise. 
  
 (a) Manner of Exercise. This Warrant may be exercised by the Registered Holder, in whole or in part, by surrendering this Warrant, with the
purchase/exercise form appended hereto as Exhibit A duly executed by such Registered Holder or by such Registered Holder’s duly authorized attorney, at the principal office of the Company, or at such other office or agency as the Company
may designate, accompanied by payment in full of the Purchase Price payable in respect of the number of shares of Warrant Stock purchased upon such exercise. The Purchase Price may be paid by cash, check, wire transfer or by the surrender of
promissory notes or other instruments representing indebtedness of the Company to the Registered Holder. 
  
 (b) Effective Time of Exercise. Each exercise of this Warrant shall be deemed to have been effected immediately prior to the close of
business on the day on which this Warrant shall have been surrendered to the Company as provided in Section 1(a) above. At such time, the person or persons in whose name or names any certificates for Warrant Stock shall be issuable upon such
exercise as provided in Section 1(d) below shall be deemed to have become the holder or holders of record of the Warrant Stock represented by such certificates. 
  

(c) Net Issue Exercise. 
  
 (i) In lieu of exercising this Warrant in the manner provided above in Section 1(a), the Registered Holder may elect to receive shares equal to the value
of this Warrant (or the portion thereof being canceled) by surrender of this Warrant at the principal office of the 

  

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Company together with notice of such election on the purchase/exercise form appended hereto as Exhibit A duly executed by such Registered Holder or
such Registered Holder’s duly authorized attorney, in which event the Company shall issue to such Registered Holder a number of shares of Warrant Stock computed using the following formula: 
  
 X = Y (A - B)  
 A 
  

			
	 Where
	 	X = The number of shares of Warrant Stock to be issued to the Registered Holder.
		
	 	 	Y = The number of shares of Warrant Stock purchasable under this Warrant (at the date of such calculation).
		
	 	 	A = The fair market value of one share of Warrant Stock (at the date of such calculation).
		
	 	 	B = The Purchase Price (as adjusted to the date of such calculation).

  
 (ii) For purposes of
this Section 1(c), the fair market value of Warrant Stock on the date of calculation shall mean with respect to each share of Warrant Stock: 
  
 (A) if the exercise is in connection with an initial public offering of the Common Stock of the Company (the “Common Stock”), and if the
Company’s Registration Statement relating to such public offering has been declared effective by the Securities and Exchange Commission, then the fair market value shall be the product of (x) the initial “Price to Public” per share
specified in the final prospectus with respect to the offering and (y) the number of shares of Common Stock into which each share of Warrant Stock is convertible at the date of calculation; 
  
 (B) if this Warrant is exercised after, and not in connection with, the
Company’s initial public offering, and the Company’s Common Stock is traded on a securities exchange or The Nasdaq Stock Market or actively traded over the counter: 
  
 (1) if the Company’s Common Stock is traded on a securities exchange or The Nasdaq Stock Market, the fair market value
shall be deemed to be the product of (x) the average of the closing prices over a 30-day period ending three days before the date of calculation and (y) the number of shares of Common Stock into which each share of Warrant Stock is convertible on
such date; or 
  
 (2) if the Company’s Common Stock is
actively traded over the counter, the fair market value shall be deemed to be the product of(x) the average of the closing bid or sales price (whichever is applicable) over the 30-day period ending three days before the date of calculation and (y)
the number of shares of Common Stock into which each share of Warrant Stock is convertible on such date; or 
  
 (C) if neither (A) nor (B) is applicable, the fair market value of Warrant Stock shall be at the highest price per share which the Company could obtain
on the date of calculation from a willing buyer (not a current employee or director) for shares of 

  

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Warrant Stock sold by the Company, from authorized but unissued shares, as determined in good faith by the Board of Directors, unless the Company is at such
time subject to an acquisition as described in Section 7(b) below, in which case the fair market value of Warrant Stock shall be deemed to be the value received by the holders of such stock pursuant to such acquisition. 
  
 (d) Delivery to Registered Holder. As soon as practicable after
the exercise of this Warrant in whole or in part, and in any event within ten (10) days thereafter, the Company at its expense will cause to be issued in the name of, and delivered to, the Registered Holder, or as such Registered Holder (upon
payment by such Registered Holder of any applicable transfer taxes) may direct: 
  
 (i) a certificate or certificates for the number of shares of Warrant Stock to which such Registered Holder shall be entitled, and 
  
 (ii) in case such exercise is in part only, a new warrant or warrants (dated the date hereof) of like tenor, calling in the
aggregate on the face or faces thereof for the number of shares of Warrant Stock equal (without giving effect to any adjustment therein) to the number of such shares called for on the face of this Warrant minus the number of such shares purchased by
the Registered Holder upon such exercise as provided in Section 1(a) or 1(c) above. 
  
 2. Adjustments. 
  
 (a) Redemption or Conversion of Preferred Stock. If all of the Preferred Stock is redeemed or converted into shares of Common Stock, then this Warrant shall automatically become exercisable for that number of shares of Common
Stock equal to the number of shares of Common Stock that would have been received if this Warrant had been exercised in full and the shares of Preferred Stock received thereupon bad been simultaneously converted into shares of Common Stock
immediately prior to such event, and the Exercise Price shall be automatically adjusted to equal the number obtained by dividing (i) the aggregate Purchase Price of the shares of Preferred Stock for which this Warrant was exercisable immediately
prior to such redemption or conversion, by (ii) the number of shares of Common Stock for which this Warrant is exercisable immediately after such redemption or conversion. 
  
 (b) Stock Splits and Dividends. If outstanding shares of the Company’s Preferred Stock shall be
subdivided into a greater number of shares or a dividend in Preferred Stock shall be paid in respect of Preferred Stock, the Purchase Price in effect immediately prior to such subdivision or at the record date of such dividend shall simultaneously
with the effectiveness of such subdivision or immediately after the record date of such dividend be proportionately reduced. If outstanding shares of Preferred Stock shall be combined into a smaller number of shares, the Purchase Price in effect
immediately prior to such combination shall, simultaneously with the effectiveness of such combination, be proportionately increased. When any adjustment is required to be made in the Purchase Price, the number of shares of Warrant Stock purchasable
upon the exercise of this Warrant shall be changed to the number determined by dividing (1) an amount equal to the number of shares issuable upon the exercise of this Warrant immediately prior to such adjustment, multiplied by the Purchase Price in
effect 

  

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immediately prior to such adjustment, by (ii) the Purchase Price in effect immediately after such adjustment. 
  
 (c) Reclassification, Etc. In case there occurs any
reclassification or change of the outstanding securities of the Company or of any reorganization of the Company (or any other corporation the stock or securities of which are at the time receivable upon the exercise of this Warrant) or any similar
corporate reorganization on or after the date hereof, then and in each such case the Registered Holder, upon the exercise hereof at any time after the consummation of such reclassification, change, or reorganization shall be entitled to receive, in
lieu of the stock or other securities and property receivable upon the exercise hereof prior to such consummation, the stock or other securities or property to which such Registered Holder would have been entitled upon such consummation if such
Registered Holder had exercised this Warrant immediately prior thereto, all subject to further adjustment pursuant to the provisions of this Section 2. 
  
 (d) Adjustment Certificate. When any adjustment is required to be made in the Warrant Stock or the Purchase Price pursuant to this Section
2, the Company shall promptly mail to the Registered Holder a certificate setting forth (i) a brief statement of the facts requiring such adjustment, (ii) the Purchase Price after such adjustment and (iii) the kind and amount of stock or other
securities or property into which this Warrant shall be exercisable after such adjustment. 
  
 (e) Acknowledgement. In order to avoid doubt, it is acknowledged that the holder of this Warrant shall be entitled to the benefit of all adjustments in the number of shares of Common Stock of the Company
issuable upon conversion of the Preferred Stock of the Company which occur prior to the exercise of this Warrant, including without limitation, any increase in the number of shares of Common Stock issuable upon conversion as a result of a dilutive
issuance of capital stock. 
  
 3. Transfers.

  
 (a) Unregistered Security. Each holder of this
Warrant acknowledges that this Warrant, the Warrant Stock and the Common Stock of the Company have not been registered under the Securities Act of 1933, as amended (the “Securities Act”), and agrees not to sell, pledge, distribute,
offer for sale, transfer or otherwise dispose of this Warrant, any Warrant Stock issued upon its exercise or any Common Stock issued upon conversion of the Warrant Stock in the absence of (i) an effective registration statement under the Securities
Act as to this Warrant, such Warrant Stock or such Common Stock and registration or qualification of this Warrant, such Warrant Stock or such Common Stock under any applicable U.S. federal or state securities law then in effect, or (ii) an exemption
from registration or qualification under the Securities Act. Each certificate or other instrument for Warrant Stock issued upon the exercise of this Warrant shall bear a legend substantially to the foregoing effect. 
  
 (b) Transferability. Subject to the provisions of Sections 3(a)
and 6 hereof, this Warrant and all rights hereunder are transferable, in whole or in part, upon surrender of the Warrant with a properly executed assignment (in the form of Exhibit B hereto) at the principal office of the Company;
provided, however, that this Warrant may not be transferred in whole or in part without the prior written consent of the Company. 
  

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 (c) Warrant Register. The Company will maintain a register containing the names and
addresses of the Registered Holders of this Warrant. Until any transfer of this Warrant is made in the warrant register, the Company may treat the Registered Holder of this Warrant as the absolute owner hereof for all purposes; provided, however,
that if this Warrant is properly assigned in blank, the Company may (but shall not be required to) treat the bearer hereof as the absolute owner hereof for all purposes, notwithstanding any notice to the contrary. Any Registered Holder may change
such Registered Holder’s address as shown on the warrant register by written notice to the Company requesting such change. 
  
 4. No Impairment. The Company will not, by amendment of its charter or through reorganization, consolidation, merger, dissolution, sale of
assets or any other voluntary action, avoid or seek to avoid the observance or performance of any of the terms of this Warrant, but will (subject to Section 15 below) at all times in good faith assist in the carrying out of all such terms and in the
taking of all such action as may be necessary or appropriate in order to protect the rights of the holder of this Warrant against impairment. 
  
 5. Representations and Warranties of the Registered Holder. The Registered Holder hereby represents and warrants to the Company that:

  
 (a) Authorization. The Registered Holder has
full power and authority to enter into this Warrant. The Warrant, when executed and delivered by the Registered Holder, will constitute a valid and legally binding obligation of the Registered Holder, enforceable in accordance with its terms, except
as limited by applicable bankruptcy, insolvency, reorganization, moratorium, fraudulent conveyance, and any other laws of general application affecting enforcement of creditors’ rights generally, and as limited by laws relating to the
availability of specific performance, injunctive relief, or other equitable remedies. 
  
 (b) Purchase Entirely for Own Account. This Warrant is issued to the Registered Holder in reliance upon the Registered Holder’s representation to the Company, which by the Registered Holder’s
acceptance of this Warrant, the Registered Holder hereby confirms, that the Warrant to be acquired by the Registered Holder, the Warrant Stock and the Common Stock to be issued upon the conversion of the Warrant Stock (collectively, the
“Securities”) will be acquired for investment for the Registered Holder’s own account, not as a nominee or agent, and not with a view to the resale or distribution of any part thereof, and that the Registered Holder has no
present intention of selling, granting any participation in, or otherwise distributing the same. By accepting this Warrant, the Registered Holder further represents that the Registered Holder does not presently have any contract, undertaking,
agreement or arrangement with any person to sell, transfer or grant participations to such person or to any third person, with respect to any of the Securities. The Registered Holder has not been formed for the specific purpose of acquiring the
Securities. 
  
 (c) Disclosure of Information. The
Registered Holder has had an opportunity to discuss the Company’s business, management, financial affairs and the terms and conditions of the offering of the Securities with the Company’s management and has had an opportunity to review the
Company’s facilities. The Registered Holder understands that such discussions, as well as any written information delivered by the Company to the Registered Holder, were intended to describe the aspects of the Company’s business which it
believes to be material. 
  

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 (d) Restricted Securities. The Registered Holder understands that the Securities have not
been, and will not be, registered under the Securities Act, by reason of a specific exemption from the registration provisions of the Securities Act which depends upon, among other things, the bona fide nature of the investment intent and the
accuracy of the Registered Holder’s representations as expressed herein. The Registered Holder understands that the Securities are “restricted securities” under applicable U.S. federal and state securities laws and that, pursuant to
these laws, the Registered Holder must hold the Securities indefinitely unless they are registered with the Securities and Exchange Commission and qualified by state authorities, or an exemption from such registration and qualification requirements
is available. The Registered Holder acknowledges that the Company has no obligation to register or qualify the Securities for resale, The Registered Holder further acknowledges that if an exemption front registration or qualification is available,
it may be conditioned on various requirements including, but not limited to, the time and manner of sale, the holding period for the Securities, and on requirements relating to the Company which are outside of the Registered Holder’s control,
and which the Company is under no obligation and may not be able to satisfy. 
  
 (e) No Public Market. The Registered Holder understands that no public market now exists for any of the securities issued by the Company, and that the Company has made no assurances that a public market
will ever exist for the Securities. 
  
 (f) Accredited or
Sophisticated Investor. The Registered Holder is an accredited investor as defined in Rule 501(a) of Regulation D promulgated under the Securities Act. 
  

6. Lock-up Agreement. 
  
 (a) Lock-up Period; Agreement. In connection with the initial public offering of the Company’s securities and upon request of the
Company or the underwriters managing such offering of the Company’s securities, the Registered Holder agrees not to sell, make any short sale of, loan, grant any option for the purchase of, or otherwise dispose of any securities of the Company
(other than those included in the registration) without the prior written consent of the Company or such underwriters, as the case may be, for such period of time (not to exceed 180 days) from the effective date of such registration as may be
requested by the Company or such managing underwriters and to execute an agreement reflecting the foregoing as may be requested by the underwriters at the time of the Company’s initial public offering. 
  
 (b) Stop-Transfer Instructions. In order to enforce the
foregoing covenants, the Company may impose stop-transfer instructions with respect to the securities of the Registered Holder (and the securities of every other person subject to the restrictions in Section 6(a)). 
  
 (c) Transferees Bound. The Registered Holder agrees that prior
to the Company’s initial public offering it will not transfer securities of the Company unless each transferee agrees in writing to be bound by all of the provisions of this Section 6. 
  
 7. Termination. This Warrant (and the right to purchase
securities upon exercise hereof) shall terminate upon the earliest to occur of the following (the “Expiration Date”): (a) 

  

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December 19, 2010, (b) the sale, conveyance or disposal of all or substantially all of the Company’s property or business or the Company’s merger
with or into or consolidation with any other corporation (other than a wholly-owned subsidiary of the Company) or any other transaction or series of related transactions in which more than fifty percent (50%) of the voting power of the Company is
disposed of, provided that this Section 7 shall not apply to a merger effected exclusively for the purpose of changing the domicile of the Company or to an equity financing in which the Company is the surviving corporation, or (c) the closing of a
firm commitment underwritten public offering pursuant to a registration statement under the Securities Act. 
  
 8. Notices of Certain Transactions. In case: 
  
 (a) the Company shall take a record of the holders of its Preferred Stock (or other stock or securities at the time deliverable upon the exercise of this
Warrant) for the purpose of entitling or enabling them to receive any dividend or other distribution, or to receive any right to subscribe for or purchase any shares of stock of any class or any other securities, or to receive any other right, or

  
 (b) of any capital reorganization of the Company, any
reclassification of the capital stock of the Company, any consolidation or merger of the Company with or into another corporation (other than a consolidation or merger in which the Company is the surviving entity), or any transfer of all or
substantially all of the assets of the Company, or 
  
 (c) of the
voluntary or involuntary dissolution, liquidation or winding-up of the Company, or 
  
 (d) of any redemption of the Preferred Stock or mandatory conversion of the Preferred Stock into Common Stock of the Company, 
  
 then, and in each such case, the Company will mail or cause to be mailed to the Registered Holder of this Warrant a notice specifying, as the case may be, (i) the date on
which a record is to be taken for the purpose of such dividend, distribution or right, and stating the amount and character of such dividend, distribution or right, or (ii) the effective date on which such reorganization, reclassification,
consolidation, merger, transfer, dissolution, liquidation, winding-up, redemption or conversion is to take place, and the time, if any is to be fixed, as of which the holders of record of Preferred Stock (or such other stock or securities at the
time deliverable upon such reorganization, reclassification, consolidation, merger, transfer, dissolution, liquidation, winding-up, redemption or conversion) are to be determined. Such notice shall be mailed at least ten (10) days prior to the
record date or effective date for the event specified in such notice. 
  
 9. Reservation of Stock. The Company will at all times reserve and keep available, solely for the issuance and delivery upon the exercise of this Warrant, such shares of Warrant Stock and other stock, securities and property,
as from time to time shall be issuable upon the exercise of this Warrant. 
  
 10. Exchange of Warrants. Upon the surrender by the Registered Holder of any Warrantor Warrants, properly endorsed, to the Company at the principal office of the Company, the Company will, subject to the
provisions of Section 3 hereof, issue and deliver to or upon the 

  

 7 

 
order of such Registered Holder, at the Company’s expense, a new Warrant or Warrants of like tenor, in the name of such Registered Holder or as such
Registered Holder (upon payment by such Registered Holder of any applicable transfer taxes) may direct, calling in the aggregate on the face or faces thereof for the number of shares of Preferred Stock called for on the face or faces of the Warrant
or Warrants so surrendered. 
  
 11. Replacement of
Warrants. Upon receipt of evidence reasonably satisfactory to the Company of the loss, theft, destruction or mutilation of this Warrant and (in the case of loss, theft or destruction) upon delivery of an indemnity agreement (with surety if
reasonably required) in an amount reasonably satisfactory to the Company, or (in the case of mutilation) upon surrender and cancellation of this Warrant, the Company will issue, in lieu thereof, a new Warrant of like tenor. 
  
 12. No Rights as Stockholder. Until the exercise of this
Warrant, the Registered Holder of this Warrant shall not have or exercise any rights by virtue hereof as a stockholder of the Company. 
  
 13. No Fractional Shares. No fractional shares of Preferred Stock will be issued in connection with any exercise hereunder. In lieu of any
fractional shares which would otherwise be issuable, the Company shall pay cash equal to the product of such fraction multiplied by the fair market value of one share of Preferred Stock on the date of exercise, as determined in good faith by the
Company’s Board of Directors. 
  
 14. Amendment or
Waiver. Any term of this Warrant may be amended or waived only by an instrument in writing signed by the party against which enforcement of the amendment or waiver is sought. 
  
 15. Headings. The headings in this Warrant are for purposes of reference only and shall not limit or otherwise
affect the meaning of any provision of this Warrant 
  
 16.
Governing Law. This Warrant shall be governed, construed and interpreted in accordance with the laws of the State of Washington, without giving effect to principles of conflicts of law. 
  
 17. Survival of Representations. Unless otherwise set forth in
this Warrant, the warranties, representations and covenants of the Company and the Purchasers contained in or made pursuant to this Warrant shall survive the execution and delivery of this Warrant. 
  
 18. Transfer: Successors and Assigns. The terms and conditions
of this Warrant shall inure to the benefit of and be binding upon the respective successors and assigns of the parties. Nothing in this Warrant, express or implied, is intended to confer upon any party other than the parties hereto or their
respective successors and assigns any rights, remedies, obligations, or liabilities under or by reason of this Warrant, except as expressly provided in this Warrant. 
  
 19. Counterparts. This Warrant may be executed in two or more counterparts, each of which shall be deemed an
original and all of which together shall constitute one instrument. 
  

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 20. Attorney’s Fees. If any action at law or in equity (including arbitration) is
necessary to enforce or interpret the terms of any of this Warrant, the prevailing party shall be entitled to reasonable attorney’s fees, costs and necessary disbursements in addition to any other relief to which such party may be entitled.

  
 21. Severability. If one or more provisions of
this Warrant are held to he unenforceable under applicable law, the parties agree to renegotiate such provision in good faith. In the event that the parties cannot reach a mutually agreeable and enforceable replacement for such provision, then (a)
such provision shall be excluded from this Warrant, (b) the balance of this Warrant shall be interpreted as if such provision were so excluded and (c) the balance of this Warrant shall be enforceable in accordance with its terms. 
  
 22. Delays or Omissions. No delay or omission to exercise any
right, power or remedy accruing to any party under this Warrant, upon any breach or default of any other party under this Warrant, shall impair any such right, power or remedy of such non-breaching or non-defaulting party nor shall it be construed
to be a waiver of any such breach or default, or an acquiescence therein, or of or in any similar breach or default thereafter occurring; nor shall any waiver of any single breach or default be deemed a waiver of any other breach or default
theretofore or thereafter occurring. Any waiver, permit, consent or approval of any kind or character on the part of any party of any breach or default under this Warrant, or any waiver on the part of any party of any provisions or conditions of
this Warrant, must be in writing and shall be effective only to the extent specifically set forth in such writing. All remedies, either under this Warrant or by law or otherwise afforded to any party, shall be cumulative and not alternative.

  
 23. Notices. Any notice required or permitted by
this Warrant shall be in writing and shall be deemed sufficient upon delivery, when delivered personally or by overnight courier or sent by fax, or 48 hours after being deposited in the U.S. mail, as certified or registered mail, with postage
prepaid, addressed to the party to be notified at such party’s address as set forth on the signature page, or as subsequently modified by written notice. 
  

24. Entire Agreement. This Warrant, and the documents referred to herein constitute the entire agreement between the parties hereto
pertaining to the subject matter hereof, and any and all other written or oral agreements relating to the subject matter hereof existing between the parties hereto are expressly canceled. 
  

			
	 XCYTE THERAPIES, INC.

		
	 By:
	 	 /s/ Ronald J. Berenson

	 Ronald J. Berenson, M.D., President

  

			
	 Address:
	    	 1124 Columbia Street

	 	    	 Suite 130

	 	    	 Seattle, WA 98104

		
	 Fax Number:
	    	 (206) 262-0900

  

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 Accepted and Agreed: 
  
 REGISTERED HOLDER 
  

			
	 /s/ Michael J. Altenburger

	 Oxford Finance Corporation

  

			
	 Address:
	 	 133 N. Fairfax Street

	 	 	 Alexandria, VA 22314

		
	 Fax Number:
	 	 703-519-5225

  

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 EXHIBIT A 
  
 PURCHASE/EXERCISE FORM 
  

	 To:     Xcyte Therapies, Inc. 
	 Dated:                                 

  
 The undersigned, pursuant to the provisions act forth in the attached Warrant
No. WPF-5, hereby irrevocably elects to (a) purchase              shares of the Preferred Stock covered by such Warrant and herewith makes payment of
$            , representing the full purchase price for such shares at the price per share provided for in such Warrant, or (b) exercise such Warrant for
             shares purchasable under the Warrant pursuant to the Net Issue Exercise provisions of Section 1(c) of the Warrant, 
  
 The undersigned acknowledges that it has reviewed the representations and
warranties contained in Section 5 of the Warrant and by its signature below hereby makes such representations and warranties to the Company as of the date hereof 
  

			
	 Signature:
	 	  

		
	 Name (print):
	 	  

		
	 Title (if applic.):
	 	  

		
	 Company.(if applic.):
	 	  

  

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 EXHIBIT B 
  
 ASSIGNMENT FORM 
  
 FOR VALUE RECEIVED,
                                        
                                     hereby sells, assigns and
transfers all of the rights of the undersigned under the attached Warrant with respect to the number of shares of Series F Preferred Stock covered thereby set forth below, unto: 
  

					
	 Name of Assignee

	 	 Address/Fax Number

	 	 No. of Shares

  

					
	 Dated:                    
	 	 Signature:
	 	  

			
	 	 	 	 	  

			
	 	 	 Witness:
	 	  

  

 12Third Amendment to Lease dated November 12, 2003.

 EXHIBIT 10.26 
  
 THIRD AMENDMENT TO LEASE 
  
 THIS THIRD AMENDMENT TO LEASE (this “Third Amendment”) is made as of this 12th day of November, 2003, by and between ALEXANDRIA REAL
ESTATE EQUITIES, INC., a Maryland corporation (“Landlord”), and XCYTE THERAPIES, INC., a Delaware corporation (“Tenant”). 
  
 RECITALS 
  
 A. Landlord and Tenant have entered into that certain Lease Agreement dated as of June 21, 1999 (the “Original Lease”), pursuant to which
Landlord leases to Tenant certain premises containing approximately 20,659 rentable square feet in the building located at 1124 Columbia Street, Seattle, Washington (the “Building”), and more particularly described in the Original
Lease (the “Original Premises”). 
  
 B. Pursuant
to that certain First Amendment to Lease dated as of October 23, 2001 (the “First Amendment”), Landlord and Tenant amended the Original Lease to, among other things, add the Expansion Space (as defined in the First Amendment) to the
Original Premises. Pursuant to that certain Second Amendment to Lease dated as of March 26, 2003 (the “Second Amendment”), Landlord and Tenant amended the Original Lease (as amended by the First Amendment) to, among other things,
(i) add the Basement Premises (as defined in the Second Amendment) to the Original Premises, and (ii) terminate the Original Lease (as modified by the First Amendment) with respect to the Expansion Space. The Original Lease, as amended by the First
Amendment and the Second Amendment is hereinafter referred to as the “Lease.” Capitalized terms used herein without definition shall have the meanings defined for such terms in the Lease. 
  
 C. Landlord and Tenant desire, subject to the terms and conditions set forth
herein, to amend the Lease to expand the size of the Original Premises by adding Suite 120 located on the first floor of the Building, consisting of approximately 2,874 rentable square feet, and more particularly shown on Exhibit A attached
hereto (the “Suite 120 Space”). 
  
 NOW,
THEREFORE, in consideration of the foregoing Recitals, which are incorporated herein by this reference, the mutual promises and conditions contained herein, and for other good and valuable consideration, the receipt and sufficiency of which are
hereby acknowledged, Landlord and Tenant hereby agree as follows: 
  

	1.	New Defined Terms. The following new defined terms are hereby added on the first page of the Original Lease after the definition of “Permitted
Use”: 

  
 Suite 120 Space:
That portion of the Project commonly known as Suite 120, containing approximately 2,874 rentable square feet, as determined by Landlord, as shown on Exhibit A to the Third Amendment. 
  
 Suite 120 Space Commencement Date: The earlier to occur of (a)
January 1, 2004, or (b) the date upon which Landlord reasonably determines that the Wall Opening (as defined in the Third Amendment) has been completed. 

 Suite 120 Space Term: The period of time commencing on the Suite 120 Space Commencement Date and
ending on June 30, 2004; provided, however, that if Tenant gives Landlord written notice of Tenant’s desire to extend the Suite 120 Space Term prior to April 30, 2004 (the “Suite 120 Extension Notice”), the Suite 120 Space Term
shall terminate on the last day of the Term. 
  
 Third
Amendment: That certain Third Amendment to Lease dated as of November 12, 2003, by and between Landlord and Tenant. 
  

	2.	Premises. The defined term “Premises” on page 1 of the Original Lease is deleted in its entirety and replaced with the following:

  
 Premises: That portion of the Project,
containing approximately 20,659 rentable square feet, as determined by Landlord, as shown on Exhibit A to the Original Lease, and that portion of the Project commonly known as Suite 70, containing approximately 700 rentable square feet, as
determined by Landlord, as shown on Exhibit A to the Second Amendment, and, during the Suite 120 Space Term, the Suite 120 Space. 
  

	3.	Base Rent. Commencing on the Suite 120 Space Commencement Date, in addition to paying Base Rent for the Premises as provided for in the Lease, Tenant shall be
required to pay Base Rent for the Suite 120 Space in the amount of $4,178.17 per month during the Suite 120 Space Term. During the Suite 120 Space Term, the defined term “Base Rent” shall mean Base Rent for the Original Premises, Base Rent
for the Basement Premises and Base Rent for the Suite 120 Space. Base Rent shall continue to be adjusted as provided for in Section 4 of the Original Lease. 

  

	4.	Operating Expenses. Commencing on the Suite 120 Space Commencement Date, in addition to paying Operating Expenses for the Original Premises as provided for in
the Original Lease, Tenant shall be required to pay Operating Expenses for the Suite 120 Space during the Suite 120 Space Term. Notwithstanding anything to the contrary contained in the second paragraph of Section 5 of the Original Lease,
during the Suite 120 Space Term, “Tenant’s First Floor Operating Expenses” shall equal 10,903 rentable square feet multiplied by the First Floor Operating Expense Rate. 

  

	5.	Delivery of Suite 120 Space. 

  
 (a) Prior to the Suite 120 Space Commencement Date, Landlord shall, at its cost and expense, open a portion of the common wall between the first
floor Premises existing on the date hereof (the “Existing First Floor Premises”) and the Suite 120 Space such that an individual is reasonably able to move directly from the Existing First Floor Premises to the Suite 120 Space and
directly back to the Existing First Floor Premises (the area so opened, the “Wall Opening”); provided, however, that Landlord shall have no obligation to install a door, door frame, hardware or otherwise mark the Wall Opening.
Tenant understands that the work required to create the Wall Opening may adversely impact Tenant’s use and occupancy of the Premises. Tenant agrees not to interfere with such work and to comply with any reasonable requirements imposed by
Landlord in connection with such work. Tenant acknowledges and agrees that Landlord shall have no 

 liability to Tenant in connection with such work and that Tenant shall not be entitled to any rental
abatement or offset in connection therewith. 
  
 (b)
Landlord shall deliver the Suite 120 Space to Tenant on the Suite 120 Space Commencement Date on an absolute “as is” basis, and (i) Tenant shall accept the Suite 120 Space in its existing condition as of the Suite 120 Space
Commencement Date, subject to all applicable Legal Requirements; (ii) Landlord shall have no obligation for any defects in the Suite 120 Space; and (iii) Tenant’s taking possession of the Suite 120 Space shall be conclusive evidence that Tenant
accepts the Suite 120 Space and that the Suite 120 Space was in good condition at the time possession was taken. Tenant agrees and acknowledges that neither Landlord nor any agent of Landlord has made any representation or warranty with respect to
the condition of any or all of the Suite 120 Space, and/or the suitability of the Suite 120 Space for the conduct of Tenant’s business, and Tenant waives any implied warranty that the Suite 120 Space is suitable for Tenant’s intended
purposes. 
  

	6.	Surrender of the Suite 120 Space. 

  
 (a) Unless Tenant timely delivers the Suite 120 Space Extension Notice to Landlord, Tenant agrees voluntarily to surrender the Suite 120 Space on
or before June 30, 2004 (“Initial Termination Date”), and in the condition which space is required under the Lease to be surrendered to Landlord at the expiration or earlier termination of the Term; provided, however, that, in
addition to the foregoing, Tenant, at its sole cost and expense, and prior to the Initial Termination Date, shall reconstruct the wall in which the Wall Opening is located to the same condition as existed immediately prior to the creation of the
Wall Opening, and otherwise in a manner satisfactory to Landlord. 
  
 (b) If Tenant timely delivers the Suite 120 Space Extension Notice to Landlord, then Tenant agrees voluntarily to surrender the Suite 120 Space on or before the last day of the Term (“Extended Termination Date”), and
in the condition which space is required under the Lease to be surrendered to Landlord at the expiration or earlier termination of the Term. 
  
 (c) Landlord and Tenant each agree that the other is excused as of the Initial Termination Date or Extended Termination Date, as applicable, from
any further obligations under the Lease with respect to the Suite 120 Space, excepting only such obligations under the Lease which are, by their terms, intended to survive a termination of the Lease, and as otherwise provided herein. In addition,
nothing herein shall be deemed to limit or terminate any common law or statutory rights Landlord may have with respect to Tenant in connection with any Hazardous Materials, or for violations of any Legal Requirements. Nothing herein shall excuse
Tenant from its obligations under the Lease with respect to the Suite 120 Space prior to the Initial Termination Date or Extended Termination Date, as applicable. 
  
 (d) In the event that Tenant fails to surrender the Suite 120 Space to Landlord in the time and manner required by
this Section 6, the provisions of Section 8 of the Lease shall apply to the Suite 120 Space. 

	7.	Miscellaneous. 

  
 (a) This Third Amendment is the entire agreement between the parties with respect to the subject matter hereof and supersedes all prior and
contemporaneous oral and written agreements and discussions. This Third Amendment may be amended only by an agreement in writing, signed by the parties hereto. 
  

(b) This Third Amendment is binding upon and shall inure to the benefit of the parties hereto, their respective agents, employees,
representatives, officers, directors, divisions, subsidiaries, affiliates, assigns, heirs, successors in interest and shareholders. 
  
 (c) This Third Amendment may be executed in any number of counterparts, each of which shall be deemed an original, but all of which when taken
together shall constitute one and the same instrument. The signature page of any counterpart may be detached therefrom without impairing the legal effect of the signature(s) thereon provided such signature page is attached to any other counterpart
identical thereto except having additional signature pages executed by other parties to this Third Amendment attached thereto. 
  
 (d) Landlord and Tenant each represent and warrant that it has not dealt with any broker, agent other person (collectively,
“Broker”) in connection with this transaction other GVA Kidder Mathews, and that no other Broker brought about this transaction. Landlord and Tenant each hereby agrees to indemnify and hold the other harmless from and against any
claims by any other Broker claiming a commission or other form of compensation by virtue of having dealt with Landlord or Tenant, as applicable, with regard to this leasing transaction. 
  
 (e) Except as amended and/or modified by this Third Amendment, the Lease is hereby ratified and confirmed and all
other terms of the Lease shall remain in full force and effect, unaltered and unchanged by this Third Amendment. In the event of any conflict between the provisions of this Third Amendment and the provisions of the Lease, the provisions of this
Third Amendment shall prevail. Whether or not specifically amended by this Third Amendment, all of the terms and provisions of the Lease are hereby amended to the extent necessary to give effect to the purpose and intent of this Third Amendment.

  
 [Signatures are on the next page.] 

 IN WITNESS WHEREOF, the parties hereto have executed this Second Amendment as of the day and year
first above written. 
  

									
	LANDLORD:	 	 	 	ALEXANDRIA REAL ESTATE EQUITIES, INC., a Maryland corporation
					
	 	 	 	 	 	 	By:	 	 /s/    Joel S. Marcus        

	 	 	 	 	 	 	 Its:
	 	 Chief Executive Officer

  

									
	TENANT:	 	 	 	 XCYTE THERAPIES, INC.,
 a Delaware corporation

					
	 	 	 	 	 	 	By:	 	 /s/    Kathi L. Cordova        

	 	 	 	 	 	 	 Its:
	 	 Senior V.P. of Finance & Treasurer

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