Document:

Exhibit
10.27

 

Fifth
Amendment to Transaction Documents

 

This
Fifth Amendment to the Transaction (this “Amendment”) is effective as of November 16, 2022 (“Effective Date”),
by and between Puritan Partners LLC, a New York limited liability company (“Puritan Partners”) and Curative Biotechnology,
Inc., a Florida corporation (the “Company”), having its principal place of business at 1825 NW Corporate Blvd., Suite
110 Boca Raton, FL 33431, each a “Party” and collectively the “Parties”. Capitalized terms used
herein without definition shall have the meanings ascribed to them in the Securities Purchase Agreement, dated as of March 2, 2022, as
amended, entered between the Parties (the “Securities Purchase Agreement”)

 

Recitals

 

WHEREAS,
pursuant to the Transaction Documents, Puritan Partners purchased a 12.5% Original Issue Discount Senior Secured Note in the
principal amount of $1,142,857.14 due March 2, 2023 ( as amended, the “Note”) and was issued a common stock purchase
warrant to purchase 22,857,143 shares of the common stock at $0.0001 exercise price ( as amended, the
“Warrant”);

 

WHEREAS, Puritan
Partners and Company are parties to the Transaction Documents, which were previously amended on August 18, 2022 , October 2, 2022,
October 14, 2022, and November 2, 2022, and the parties now desire to further amend the respective Transaction Documents in
accordance with the terms of this Amendment.

 

NOW,
THEREFORE, in consideration of the following and other consideration, the receipt of which is hereby acknowledged, the parties agree
as follows:

 

		a)	Monthly
                                            Redemption Date. The definition of “Monthly Redemption Date” set forth in Section
1 of the Note is deleted in its entirety and hereby replaced with the following:

 

“Monthly
Redemption Date” means the second of each month, commencing immediately upon December 17, 2022, and terminating upon the full
redemption of this Note. Provided however that upon completion of a Qualified Offering, the entire outstanding balance of the Note will
be due and payable at closing of the Qualified Offering.

 

		(b)	Monthly
                                            Redemption Amount. The definition of “Monthly Redemption Amount” set forth in
                                            Section 1 of the Note is deleted in its entirety and hereby replaced with the following:

 

“Monthly
Redemption Amount” means, as to a Monthly Redemption, one fourth of the original principal amount at 110% of such principal
amount, plus accrued but unpaid interest, liquidated damages and any other amounts then owing to the Holder in respect of this Note.

 

		(c)	The
                                            interest on the Note that is due and payable on December 2, 2022 as well as any other unpaid
                                            accrued and unpaid interest, shall instead be due and payable on the earlier of (i) December
                                            17, 2022 and (ii) the closing of the Qualified Offering.

	 	 	 
	 	(d)	In
                                            further consideration for extending by one month the straight-line amortization payment requirement
                                            under the Note, the Company agrees that (i) the number of shares underlying the Warrant shall
                                            be increased from 26,666,667 shares to 28,571,429shares (which amount may be subject to adjustment
                                            per the terms of the Warrant) and (ii) upon the closing of Company’s offering being
                                            registered pursuant to the S-1 Registration Statement (Registration. No. 333-264339), the
                                            outstanding principal balance, along with any accrued interest, fees or costs, will be repaid,
                                            in full pursuant to either the Optional Redemption provisions contained in Section 5(a) of
                                            the Note or the Mandatory Prepayment provisions contained in Section 5(d) of the Note, as
                                            the case may be.

 

    	 

     

    

 

Each
of the undersigned has caused this Amendment to be duly executed and delivered as of the date first written above and will become effective
as of the Effective Date.

 

	 	CURATIVE BIOTECHNOLOGY, INC.
	 	 	 
	 	By:	 
	 	Name:	Richard
    Garr                  
	 	Title:	Chief
    Executive Officer

 

	 	Puritan Partners LLC
	 	 	 
	 	By:	
	 	Name:	Richard
    Smithline
	 	Title:	Managing
    MemberExhibit 10.19

 

PRIVATE AGREEMENT

 

FOR THE EXTENSION OF THE SPONSORSHIP AGREEMENT

 

between

 

Brera Milano S.r.l., Tax Code (C.F. 09703750969),
with registered office in via Ripamonti 1/3, Milan (Italy), a company incorporated under Italian law, in the person of its pro tempore
legal representative Marco Sala, (the "Sponsor"),

 

and

 

Fudbalsky Klub Akademija Pandev, with registered
office at Spiro Zahov 28, Strumica (North Macedonia), a company incorporated under Macedonian law, (hereinafter, for the sake of brevity,
also referred to as "FKAP"), in the person of its pro tempore legal representative Goran Pandev, also in his capacity
as full and exclusive owner of the FKAP, (the "Sponsee"),

 

hereinafter also referred to as “the Parties”,

 

WHEREAS:

 

		-	On
16 August 2022 Brera Milano S.r.l., formerly KAP S.r.l., and FKAP entered into a non-exclusive sponsorship agreement (the "Sponsoring
Agreement") - which is attached to this document under Annex A, constituting an integral part thereof – by virtue of which
the Sponsee has granted the Sponsor the right to qualify as "Main Sponsor" and to use the name and logo of "Fudbalsky
Klub Akademija Pandev" in all communication campaigns of the Sponsor itself (see Annex A, art. 2 );

 

		-	The
validity of the Sponsorship Agreement was agreed between the Parties from the signing date of 16 August 2022 until 30 June 2022 (recte:
30 June 2023) (see Annex A, art. 7);

 

		-	By
way of consideration, the Sponsor paid FKAP the agreed amount of Euro 70,000 (seventy thousand);

 

		-	Pursuant
to the Sponsorship Contract, the Parties have agreed that any modification must be agreed to in writing (see Annex A, art. 11);

 

		-	It
is now the intention of the Parties to extend the validity of the Sponsorship Agreement under the terms and conditions agreed herein;

 

With all the above stated, to form an integral
part of this agreement,

 

IT IS AGREED

 

as follows.

 

		1.	Brera Milano S.r.l. and Fudbalsky Klub Akademija Pandev agree
to extend the validity of the Sponsorship Agreement to 31 December 2023, without prejudice to the exclusion of tacit renewal.

 

		2.	The Parties agree that Brera Milano S.r.l. undertakes to pay
FKAP the amount of Euro 30,000 (thirty thousand) by way of consideration within ten days of the signing of this agreement. Said payment
must be made by bank transfer on the basis of the coordinates already known to the Sponsor (see Annex A, art. 5).

 

     

     

    

 

		3.	It is expressly understood between the Parties that the failure,
or inexact or non-punctual fulfillment of the payment agreed in the previous art. 2 will produce the effect of the legal termination
of this agreement pursuant to art. 1456 of the Italian civil code.

 

In such an event, this writing shall
become null and void, without prejudice to the validity of the current Sponsorship Contract under Attachment A.

 

		4.	Except for what expressly agreed herein, the Parties mutually
acknowledge that any residual agreement of the Sponsorship Agreement remains firm, in the terms governed therein.

 

		5.	Any modification of this agreement shall be agreed in writing
between the Parties.

 

		6.	Any and all confidentiality obligations provided for in the
Sponsorship Agreement remain valid and also apply to what is hereby agreed (see Annex A, art. 12).

 

		7.	What is agreed to in this document is subject to the application
of Italian law and to the competence of the Italian jurisdiction.

 

Any disputes as may arise in relation
to this private agreement, including, for example but not by way of limitation, any disputes relating to its validity, effectiveness,
interpretation, execution, and resolution, will be the exclusive jurisdiction of the Court of Milan.

 

		8.	The Parties mutually acknowledge that the terms covered by this
agreement are the result of their common will and of free negotiations between them, without prejudice to the application of articles 1341
and 1342 of the Italian Civil Code.

 

Read, confirmed and signed.

 

Milan, 25 November 2022

 

	Brera Milano S.r.l.	 	Fudbalsky Klub Akademija Pandev
	 	 	 
	Marco Sala	 	Goran Pandev
	 	 	 
	/s/ Marco Sala	 	/s/ Goran PandevExhibit 10.20

 

PRIVATE AGREEMENT

 

between

 

Brera Holdings PLC with registered office
in Connaught House, 5th Floor, One Burlington Road, Dublin 4, D04 C5Y6, Ireland, a company incorporated under Irish law, registered with
the Dublin Companies Registrar under no. 721923, Italian tax code 91058900, in the person of its pro tempore legal representative
Sergio Scalpelli,

 

and

 

Marco Sala, born in Lecco on 17 August
1981, domiciled in Milan, via Gargano n. 46, tax code SLA MRC 81M17 E507,

 

hereinafter also jointly referred to as “the
Parties”,

 

WHEREAS:

 

		-	On 21 June 2018, Mr. Marco Sala was appointed,
until revocation, Sole Director of Brera Milano S.r.l., formerly KAP S.r.l., Tax Code and Business Registry number 09703750969, with registered
office in Milan, via Ripamonti n. 1/3;

 

		-	On 29 July 2022, Brera Holdings PLC purchased
the shares representing the entire share capital of Brera Milano S.r.l., becoming its sole shareholder;

 

		-	It is the intention of Brera Holdings PLC to
appoint a new Sole Director to replace Mr. Marco Sala, preventing the onset of any conflicts;

 

		-	Mr. Marco Sala is willing to voluntarily resign
from office;

 

		-	Mr. Marco Sala, as Sole Director of Brera Milano
S.r.l., is still a creditor towards the same Brera Milano S.r.l. for the amount of approximately Euro 43,000 (forty-three thousand) by
way of residual emoluments for the office, accrued during the current year 2022 and not paid by the company;

 

		-	Mr. Marco Sala claims the right to receive from
Brera Milano S.r.l. an indemnity of Euro 11,000 (eleven thousand) by way of severance;

 

		-	The Parties therefore intend to reach an amicable
agreement to settle any pending issues, current or potential, that may find a basis in the organic relationship between Mr. Marco Sala
and Brera Milano S.r.l.;

 

With all the above stated, to form an integral
part of this agreement,

 

     

     

    

 

IT IS AGREED

 

as follows.

 

		1.	Mr. Marco Sala undertakes to resign from the position of Sole Director of Brera Milano S.r.l. during the
ordinary shareholders’ meeting of the company to be held today in full form.

 

		2.	Mr. Marco Sala undertakes to forfeit, and hereby forfeits, to receive from Brera Milano S.r.l. the residual
amount of approximately Euro 43,000 (forty-three thousand) by way of emoluments for the position of Sole Director accrued and not paid
by Brera Milano S.r.l. during the current year 2022, also acknowledging it at the shareholders’ meeting.

 

		3.	Mr. Marco Sala also undertakes to forfeit, and hereby forfeits, to receive from Brera Milano S.r.l. the
indemnity of Euro 11,000 (eleven thousand) which would be due to him by way of severance, also acknowledging it at the meeting.

 

		4.	As consideration for the commitments assumed by Mr. Marco Sala referred to at points 1., 2. and 3. of
the present agreement, Brera Holdings PLC undertakes to pay Mr. Marco Sala the total and all-inclusive amount of Euro 43,000 (forty-three
thousand.)

 

		5.	The Parties agree that Brera Holdings PLC will make the payment of the agreed amount of Euro 43,000 (forty-three
thousand) referred to at point 4 above within 5 (five) days of the signing of this agreement and on the condition of effective fulfillment
of the commitments undertaken by Mr. Marco Sala referred to at points 1., 2. and 3. of this agreement.

 

Said payment shall be made by bank
transfer to Mr. Marco Sala’s bank account: IBAN IT94B0347501605CC0010437860.

 

		6.	With the exact fulfillment of the payment obligation agreed to per point 4. above, Mr. Marco Sala, also
recalling the waivers referred to at points 2. and 3. of the present agreement, acknowledges that he expects nothing else from Brera Milano
S.r.l. for any title, reason, or cause, particularly in relation to the office of Sole Director of Brera Milano S.r.l. and of the relevant
activity carried out by him in that capacity.

 

		7.	With the exact fulfillment of the commitments assumed by Mr. Marco Sala referred to at points 1., 2. and
3. above, Brera Holdings PLC thanks Mr. Marco Sala for the work done and declares that it recognizes Mr. Marco Sala ample discharge for
the work carried out during his tenure as Sole Director of Brera Milano S.r.l.

 

		8.	What agreed to in the present agreement is subject to Italian law and to the competence of the Italian
jurisdiction.

 

Any and all disputes that might arise
in relation to this private agreement, including, by way of example but not of limitation, those relating to its validity, effectiveness,
interpretation, execution and resolution, will be the exclusive jurisdiction of the Court of Milan.

 

		9.	The Parties mutually acknowledge that the agreements covered by this document are the result of their
common will and of free negotiations between them, without prejudice to the application of articles 1341 and 1342 of the Italian civil
code.

 

Read, confirmed and signed.

 

Milan, 30 November 2022

 

	Brera Holdings PLC	 	Marco Sala
	Sergio Scalpelli	 	/s/ Marco Sala
	/s/ Sergio Scalpelli

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