Document:

Second Amendment to Lease

 EXHIBIT 10.1 
 SECOND AMENDMENT TO LEASE 
 (NORTH CREEK CORPORATE CENTER) 

THIS SECOND AMENDMENT TO LEASE (“Second Amendment”) is made and entered into as of the 26th day of April, 2011 by
and between ARDEN REALTY LIMITED PARTNERSHIP, a Maryland limited partnership (“Landlord”) and SCOLR PHARMA, INC., a Delaware corporation (“Tenant”). 

R E C I T A L S : 

A. Landlord and Tenant entered into that certain Standard Multi-Tenant Lease dated as of June 19, 2008 (the “Original
Lease”), as amended by that certain First Amendment to Lease dated as of November 5, 2009 (the “First Amendment”), whereby Landlord leases to Tenant and Tenant leases from Landlord certain space located in that
certain building commonly known as North Creek Corporate Center located and addressed at 19204 Northcreek Parkway, Bothell, Washington (the “Building”). The Original Lease, as amended by the First Amendment, shall herein be
referred to, collectively, as the “Lease.” 
 B. Tenant currently subleases (i) a portion of the
Premises (as defined in Section 1 below) to Cancer Targeted Technology LLC, A Delaware limited liability company (“CTT”) pursuant to that certain Sublease dated as of January 17, 2011 by and between Tenant and CTT (the
“CTT Sublease”) and (ii) a portion of the Premises to Nanomaterials Discovery Corporation (“Nano”) pursuant to that certain Sublease dated March 15, 2010 by and between Tenant and Nano (the
“Nano Sublease”). The CTT Sublease and Nano Sublease may be referred to herein collectively, as the “Existing Subleases.” 
 C. Pursuant to Article 4 of the Original Lease (as amended by Sections 5 and 6 of the First Amendment), as of the date of the Default Notice (as defined below), Landlord held a cash security deposit (the
“Existing Security Deposit”) in the amount of Thirty-Eight Thousand Eight Six Hundred Twenty-Nine and No/100 Dollars ($38,629.00) and was the beneficiary under a Letter of Credit issued by Silicon Valley Bank (the
“Letter of Credit”) with a Stated Amount of Two Hundred Fifty-Seven Thousand Four Hundred Six and No/100 Dollars ($257,406.00). 
 D. Tenant acknowledges that as of April 7, 2011, it was delinquent in the payment of Monthly Basic Rental and Additional Rent (including, without limitation, unpaid amounts related to Tenant’s
Proportionate Share of Direct Costs and late charges) payable by Tenant under the Lease in the amount of Sixty-Three Thousand Seven and 51/100 Dollars ($63,007.51) (the “Delinquent Rent”). In connection with Tenant’s
failure to pay the Delinquent Rent, Landlord delivered to Tenant a Notice to pay Rent or Surrender Premises (the “Default Notice”) on April 7, 2011. Tenant subsequently failed to pay the Delinquent Rent within the cure
period provided in the Lease and consequently, as further provided in this Second Amendment below, and as authorized under the Lease, Landlord applied the Existing Security Deposit against Tenant’s obligation to pay the Delinquent Rent and drew
upon the entire Stated Amount of the Letter of Credit (the “Draw”). 
 E. By this Second Amendment,
Landlord and Tenant now desire to: (i) provide for an early termination of the Lease, (ii) reduce the amount of Monthly Basic Rental and Tenant’s Proportionate Share of Direct Costs payable by Tenant under the Lease, and
(iii) otherwise modify the Lease as provided herein. 

 F. Unless otherwise defined herein, capitalized terms as used herein shall have the same
meanings as given thereto in the Original Lease. 
 NOW, THEREFORE, in consideration of the foregoing recitals and the mutual
covenants contained herein, and for other good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the parties hereto agree as follows: 
 A G R E E M E N T : 

1. The Premises. Landlord and Tenant hereby agree that pursuant to the Lease, Landlord currently, as of the date of this Second
Amendment, leases to Tenant and Tenant currently leases from Landlord that certain space located in the Building and containing a total of 15,516 rentable square feet (the “Premises”). The Premises is comprised of 4,507
rentable square feet of office space, 8,939 rentable square feet of laboratory space and 2,169 rentable square feet of warehouse space, all as further depicted on Exhibit “A” to the First Amendment. 

2. Cure of Default. Landlord agrees that, as of the date of this Second Amendment, and following Landlord’s actions referred
to in Recital D above, the Delinquent Rent has been paid by Tenant under the Lease and the Event of Default that is the subject of the Default Notice has been cured. 
 3. Reduced Term. Pursuant to the Lease, the Lease Expiration Date is currently as of the date of this Second Amendment, January 31, 2016 (the “Current Expiration
Date”). However, effective as of the date of this Second Amendment, the Current Expiration Date shall be accelerated such that the Lease shall terminate on March 31, 2012 (“New Expiration Date”). The period from
May 1, 2011 through the New Expiration Date specified above, shall be referred to herein as the “Reduced Term.” Tenant shall not have any right to extend the Lease beyond the Reduced Term and consequently, Article 31 of
the Original Lease is hereby deleted and shall be null and void. 
 4. Reduced Monthly Basic Rental.
Notwithstanding anything to the contrary in the Lease, during the Reduced Term, Tenant shall pay, in accordance with the provisions of this Section 4, Monthly Basic Rental for the Premises in the amount of Eleven Thousand Fifty and No/100
Dollars ($11,050.00) per month (which amount shall also be deemed to satisfy Tenant’s obligation to pay Tenant’s Proportionate Share of any Direct Costs during the Reduced Term) (the “Reduced Rent”). In addition to
paying Reduced Rent, Tenant shall remain responsible at all times during the Reduced Term for the payment of all of its other monetary obligations under the Lease (as amended hereby) including, without limitation, Tenant’s obligation to pay for
all utility usage in the Premises as set forth in Article 11 of the Original Lease. The Reduced Rent shall be payable on the first (1st) day of each month in advance during the Reduced Term, at the same time and in the same manner as Monthly Basic
Rental for the Premises. Tenant and Landlord hereby acknowledge that during the Reduced Term, Tenant’s Proportionate Share of any Direct Costs, required to be paid by Tenant under the Lease shall be paid by Tenant as part of the Reduced Rent
and Tenant agrees that Landlord may allocate any portion of the Reduced 

  
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Rent to Direct Costs as Landlord may from time to time in its sole discretion determine to be appropriate. In addition, Tenant agrees that Landlord shall not be obligated to provide Tenant with
any Estimate Statement and/or Statement relating to the actual and/or estimated Direct Costs for any accounting period during the Reduced Term and/or Landlord’s allocation of the Reduced Rent paid by Tenant to such charges. 

5. Consideration to Landlord. Tenant agrees that as material consideration for Landlord’s agreement to enter into this Second
Amendment and to provide the substantial benefits to Tenant hereunder, including without limitation, the Reduced Term set forth in Section 3 above, the Reduced Rent set forth in Section 4 above, and the cancellation of the default and
preservation of the Lease notwithstanding the expiration of cure period set forth in the Default Notice as described in Recital D above, Landlord shall be entitled to retain as a fee (the “Consideration Fee”), without
liability to Tenant, (i) the Existing Security Deposit as set forth in Recital D above, which Tenant hereby relinquishes to Landlord, and (ii) the proceeds of the Draw on the LC, which the issuing bank paid to Landlord. Tenant further
agrees that the Draw was permissible under the Lease and that to the extent necessary, Section 4(b) of the Original Lease (as previously modified by Section 5 of the First Amendment) is hereby deemed to be amended to confirm that Landlord
may retain as its sole property the Consideration Fee. Landlord hereby agrees that Tenant shall not be required to restore (a) the Security Deposit to its full amount and/or (b) the Letter of Credit. 

6. Landlord Termination Right/Right to Market Premises. Notwithstanding any contrary provision in the Lease, and in addition to
any other right of termination that Landlord may have under the Lease, Landlord shall have the right (“Landlord’s Termination Right”), at no additional cost to Landlord, to terminate the Lease (as amended by this Second
Amendment) at any time after the mutual execution and delivery of this Second Amendment by Landlord and Tenant, upon not less than seventy-five (75) days prior written notice to Tenant. On or before the effective date of such termination (the
“Landlord Termination Date”), Tenant shall pay to Landlord any unpaid rent due under the Lease, as amended hereby through the Landlord Termination Date, which rent shall be prorated for any partial month prior to the
Termination Date. In addition to any entry rights of Landlord set forth in the Lease, during the Reduced Term, Landlord shall have the right to market the Premises for lease and, upon at least twenty-four (24) hours prior written or verbal
notice to Tenant, to exhibit all or any portion of the Premises to prospective tenants. 
 7. Confidentiality. Tenant
acknowledges that the terms of this Second Amendment have been negotiated between Landlord and Tenant based upon particular and unique circumstances, and that it is of the utmost importance to Landlord that the terms of this Second Amendment not be
disclosed to any third parties, including without limitation, other tenants or occupants of the Building. Therefore Tenant, on behalf of itself and its employees, agents and contractors, agrees not to disclose the terms of this Second Amendment to
any third parties, including without limitation, other tenants or occupants of the Building other than to Tenant’s agents, employees, financial and legal consultants, provided, however, that Tenant may disclose the terms to its lenders,
purchasers, investors, and subtenants under the Existing Subleases or pursuant to any regulatory or legal obligation, including without limitation applicable requirements of the U.S. Securities and Exchange Commission or any securities exchange on
which Tenants securities are listed. In the event that Tenant breaches the provisions of this Section 5, then Landlord shall be 

  
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entitled to recover any and all damages incurred by Landlord as a result of Tenant’s breach and pursue any and all other rights and remedies against Tenant for such breach as provided under
the Lease (as amended hereby) and as otherwise provided by law or in equity. 
 8. Right of First Offer. Effective as of
the Effective Date hereof, Article 32 of the Original Lease is deleted in its entirety and shall have no further force or effect. 
 9. Release of Liability. As a material inducement to Landlord for entering into this Second Amendment, Tenant, for itself, and for all of its successors-in-interest, assigns, heirs, executors,
agents, representatives, consultants, transferees, predecessors, employees, directors, shareholders, affiliates, partners, co-venturers, attorneys, insurers, administrators, and all others who may take any interest in the matters herein released,
does fully and forever release, acquit and discharge Landlord and Landlord’s successors-in-interest, assigns, heirs, executors, agents, representatives, consultants, transferees, predecessors, employees, affiliates, partners, co-venturers,
attorneys, insurers, and administrators from any and all causes of action, charges, claims, costs, damages, losses, debts, demands, expenses, fees, liabilities, and/or obligations of every nature, character and description which either may have
against Landlord as of the date of full execution and delivery of this Second Amendment by Landlord and Tenant, whether known or unknown, arising out of or related to the Lease, the Premises, the Building and/or drawing down the entire $257,406.00
Letter of Credit in April 2011 and applying such Letter of Credit proceeds as set forth herein. 
 10. Overriding
Agreement. Landlord’s agreement to reduce the obligations of Tenant under the Lease as set forth above in this Second Amendment is expressly conditioned upon Landlord receiving and retaining each and every benefit of its bargain under this
Second Amendment, expressly including, without limitation, the ability to receive, retain, and apply the Consideration Fee as set forth in Section 5 above. Tenant hereby agrees and acknowledges that without being able to retain the
Consideration Fee, Landlord would not agree to the concessions granted to Tenant in this Second Amendment and accordingly, notwithstanding anything to the contrary contained in this Second Amendment, if (i) Tenant, a creditor or shareholder of
Tenant, or any other party files a lawsuit, petition, motion, or other similar proceeding (however styled, an “Action”) seeking to, or (ii) any court of competent jurisdiction grants relief in any such Action that does:
(A) avoid or set aside any transfer of value by Tenant (or on Tenant’s behalf) to Landlord, including without limitation, the Consideration Fee, or (B) secure any other relief that would have the effect of frustrating the intent of
the parties as evidenced by this Second Amendment (any such action, a “Challenge”), then the concessions granted by Landlord herein shall be void ab initio and in such event, this Second Amendment shall be of no force or
effect and Landlord shall be entitled to retain and apply the Consideration Fee and any other payments made under the terms of this Second Amendment to Tenant’s obligation to pay Monthly Basic Rental and Tenant’s Proportionate Share of any
Direct Costs in the amounts stated in the Lease during the Term (which in such case, shall be expire on January 31, 2016) without regard to this Second Amendment. 
 11. Brokers. Each party represents and warrants to the other that no broker, agent or finder negotiated or was instrumental in negotiating or consummating this Second Amendment. Each party further
agrees to defend, indemnify and hold harmless the other party from and against any claim for commission or finder’s fee by any person or entity who claims or alleges that they were retained or engaged by the indemnifying party or at the request
of such party in connection with this Second Amendment. 

  
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 12. Tenant Representations. Each person executing this Second Amendment on behalf of
Tenant represents and warrants to Landlord that: (a) Tenant is properly formed and validly existing under the laws of the state in which Tenant is formed and Tenant is authorized to transact business in the state in which the Building is
located; (b) Tenant has full right and authority to enter into this Second Amendment and to perform all of Tenant's obligations hereunder; and (c) each person (and both persons if more than one signs) signing this Second Amendment on
behalf of Tenant is duly and validly authorized to do so. 
 13. Time of the Essence. Time is of the essence in this
Second Amendment and the provisions contained herein. 
 14. Further Assurances. Landlord and Tenant hereby agree to
execute such further documents or instruments as may be necessary or appropriate to carry out the intention of this Second Amendment. 
 15. Voluntary Agreement. Tenant has read this Second Amendment and the release as contained herein, and on the advice of counsel Tenant has freely and voluntarily entered into this Second
Amendment. 
 16. Counterparts and Fax Signatures. This Second Amendment may be executed in counterparts, each of which
shall be deemed an original, but such counterparts, when taken together, shall constitute one agreement. This Second Amendment may be executed by a party's signature transmitted by facsimile or other electronic means (collectively,
“faxed signatures”), and copies of this Second Amendment executed and delivered by means of faxed signatures shall have the same force and effect as copies hereof executed and delivered with original signatures. All parties
hereto may rely upon faxed signatures as if such signatures were originals. Any party executing and delivering this Second Amendment by facsimile or other electronic means shall promptly thereafter deliver a counterpart signature page of this Second
Amendment containing said party's original signature. All parties hereto agree that a faxed signature page may be introduced into evidence in any proceeding arising out of or related to this Second Amendment as if it were an original signature page.

 17. No Further Modification. Except as set forth in this Second Amendment, all of the terms and provisions of the
Lease shall remain unmodified and in full force and effect. Effective as of the date hereof, all references to the "Lease" shall refer to the Lease as amended by this Second Amendment. 

[SIGNATURES ATTACHED HERETO] 

  
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 IN WITNESS WHEREOF, this Second Amendment has been executed as of the day and year first
above written. 
  

									
	 “LANDLORD”
	  	 ARDEN REALTY LIMITED PARTNERSHIP,
 a Maryland limited partnership

			
		  	By:	  	 ARDEN REALTY, INC.,
 a Maryland corporation
 Its: Sole General Partner

				
		  		  	By:	  	 /s/ JOAQUIN DE MONET

		  		  		  	Its:	  	 PRESIDENT & CEO

 

					
	 “TENANT”
	  		  	 SCOLR PHARMA, INC.,
 a
Delaware corporation

			
		  	By:	  	 /s/ RICHARD M. LEVY

		  	 Print Name:Richard M.
Levy                                        
                    
 Title:Executive
Vice President and Chief Financial

Officer                        
                                         
                               

[NOTARY ACKNOWLEDGEMENTS ATTACHED HERETO] 

  
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	State of Washington	 	)
		
	County of King	 	)

 Subscribed and
sworn to (or affirmed) before me on this 19th day of
April, 2011, by Richard M. Levy, proved to me on the basis of satisfactory evidence to be the person(s) who appeared before me. 
  

	
	Seal:
                                         
                                   
	
	Signature /s/ JESSIE STEWART BROWN

  

			
	State of	 	)
		
	County of                           
                          	 	)

 Subscribed and sworn to (or affirmed)
before me on this      day of             , 2011, by
                                , proved to me on the basis of satisfactory
evidence to be the person(s) who appeared before me. 
  

	
	Seal:
                                         
                                   
	
	Signature
                                         
                           

  
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	State of California	 	)
		
	County of Los Angeles	 	)

 Subscribed and sworn to (or affirmed)
before me on this 25 day of April, 2011, by Joaquin de Monet, proved to me on the basis of satisfactory evidence to be the person(s) who appeared before me. 
  

	
	Seal:
                                         
                                   
	
	Signature /s/ SHERRY M. HUNTER-FINE

  
 -8-Amendment to Executive Employment Agreement

 EXHIBIT 10.2 
 AMENDMENT TO 
 EXECUTIVE EMPLOYMENT AGREEMENT 

Stephen J. Turner 
 THIS AMENDMENT TO EXECUTIVE EMPLOYMENT AGREEMENT (“Amendment”) is made and entered into as of the last date set forth on the Signature Page hereof, to be effective immediately, by and
between SCOLR Pharma, Inc. a Delaware corporation (“SCOLR”), and Stephen J. Turner (“Executive”). 
 Recitals 
 A. Executive is currently an employee of SCOLR pursuant to the
terms of that certain Employment Agreement dated April 14, 2008, as amended or modified prior to the date hereof (the “Current Employment Agreement”). 
 B. This Amendment is entered into in order to modify the terms of the Severance and Change in Control provisions of the Current Employment Agreement. 

NOW, THEREFORE, for and in consideration of the premises and of the mutual covenants and agreements hereinafter stipulated, the parties
agree the following provisions should be incorporated into the existing Agreement, and should a conflict in provisions arise, the provisions of the Amendment should control. 
 Agreement 
 1. Amendments. 

Section 7.3 Termination Without Cause by the Company. Section 7.3 is hereby amended and restated in its entirety to read:

 7.3 Termination Without Cause by Company. Company may terminate Executive’s employment without Cause at any time
on thirty (30) days’ advance written notice to Executive, provided that Company may, in its sole discretion, elect to waive all or any part of such notice period. In the event of such termination, and contingent on the satisfaction of the
conditions outlined in Section 7.6 below (the “Severance Conditions”), Executive will be paid the Standard Entitlements and the Severance Package (defined below). Executive will be paid the Standard Entitlements for the
duration of the required notice period, even if Company elects to relieve Executive of Executive’s duties at an earlier time. All other Company obligations to Executive pursuant to this Agreement will be automatically terminated and completely
extinguished. 
 For purposes of this Agreement, the “Severance Package” shall consist of: 

  
 Page 1 – AMENDMENT TO
EXECUTIVE EMPLOYMENT AGREEMENT 

 (a) a one time payment of Seventy-Five Thousand and No/100 Dollars ($75,000.00); and

 (b) 100% acceleration of vesting, as of the termination date, of all of the then un-vested equity awards under any employee
benefit plan of Company held by Executive at the time of such termination or resignation for Good Reason (as defined below). 

Section 7.4 Voluntary Resignation by Executive for Good Reason Following a Change in Control. A new Section 7.4 is
hereby amended and restated in its entirety to read: 
 7.4 Voluntary Resignation by Executive for Good Reason Following a
Change in Control. In the event that in connection with or within twelve (12) months following a Change in Control (as defined below) Executive resigns for Good Reason (as defined below), following thirty (30) days’ advance
written notice to Company, provided that Company may, in its sole discretion, elect to waive all or any part of such notice period, Executive will be entitled to receive the Standard Entitlements and a one time payment of two times the cash amount
due under the Severance Package (a total of One Hundred Fifty Thousand and No/100 Dollars ($150,000.00)) as well as the non-cash elements of the Severance Package, contingent on the satisfaction of the Severance Conditions. As long as Executive
provides the required notice, Executive will be paid the Standard Entitlements for the duration of the required notice period, even if Company elects to relieve Executive of Executive’s duties at an earlier time. All other Company obligations
to Executive pursuant to this Agreement will become automatically terminated and completely extinguished. 
 Executive will be
deemed to have resigned for “Good Reason” if Executive resigns within ninety (90) days after any of the following have occurred, without Executive’s written consent: 

(a) Company reduces the level of Executive’s responsibility or changes Executive’s duties so that Executive’s duties are no
longer consistent with the position of a senior executive; 
 (b) Company reduces Executive’s Base Salary by more than ten
percent (10%), unless such reduction is made as part of, and is generally consistent with, a general reduction of senior executives’ compensation; 
 (c) Company relocates Executive’s principal place of work to a location more than fifty (50) miles from the location specified in Section 2.3; or 

(d) Company fails to assign the terms of this Agreement to any successors contemplated in Section 16.1. 

  
 Page 2 – AMENDMENT TO
EXECUTIVE EMPLOYMENT AGREEMENT 

 Notwithstanding the foregoing, Executive’s resignation as a result of any of the
foregoing conditions shall be considered a Voluntary Termination by Executive (as described in Section 7.1) unless Executive shall have provided written notification to the Company of the condition(s) allegedly constituting Good Reason and
Company shall have failed to correct such condition(s) within ten (10) days after Company’s receipt of such notice. 

2. Other Terms Unchanged. Except as expressly amended in this Agreement, the terms and conditions of the Current Employment
Agreement remain in full force and effect without modification. 
 3. Legal Counsel. Executive acknowledges having been
advised that the Company’s legal counsel does not represent the Executive in connection with the Current Employment Agreement or this Amendment. Executive further acknowledges having been afforded the opportunity to review and revise this
Amendment and to seek and obtain independent personal legal counsel in connection with the negotiation, review and execution of this Amendment. 
 [Remainder of this Page is Intentionally Blank] 

  
 Page 3 – AMENDMENT TO
EXECUTIVE EMPLOYMENT AGREEMENT 

 IN WITNESS WHEREOF, the parties have caused this Amendment to Executive Employment Agreement
to be executed to be effective as of the date of signing. 
  

									
	EXECUTIVE	 		 		 	SCOLR PHARMA, INC.
				
	 /s/ STEPHEN J. TURNER
	 		 	By:	 	 /s/ CARL J. JOHNSON

	Name: Stephen J. Turner	 		 		 	Name: CARL J. JOHNSON
		 		 		 		 	Title: CHAIRMAN
			
	 4/26/11
	 		 	 4/19/2011

	Date	 		 		 	Date	 	

  
 Page 4 – AMENDMENT TO
EXECUTIVE EMPLOYMENT AGREEMENT

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