Document:

EX-10.14

 Exhibit 10.14 

SHARE RESTRICTION DEED 

THIS SHARE RESTRICTION DEED (this “Deed”) is made and entered into as of January 3, 2018 by and among Qtech Ltd.,
an exempted company duly incorporated and validly existing under the laws of the Cayman Islands (the “Company”), Li Lei (李磊), a citizen of the People’s Republic of China (the “Principal”), and News Optimizer (BVI) Ltd., a company duly incorporated and validly existing under the laws of the
British Virgin Islands (the “Principal Holding Company/ies”). 
 In consideration of the foregoing recitals
and the mutual promises hereinafter set forth, the sufficiency and adequacy of which consideration the parties hereby acknowledge, the parties hereto, intending to be legally bound, agree as follows. Unless otherwise provided herein, capitalized
terms shall have the meanings ascribed to them in the then effective Memorandum and Articles of Association of the Company (as amended and restated from time to time). 

1.    Obligation to Sell Principal’s Shares. 

1.1    General. 

(A)    3,750,000 Ordinary Shares held by the Principal through the Principal Holding Company(ies) (as appropriately
adjusted for share splits, combinations, reorganizations and any similar event, representing 50% of all the Ordinary Shares held by the Principal through the Principal Holding Company(ies) as of the date of consummation of the subscription of the
Series A1 Preferred Shares of the Company) that have not become vested pursuant to Section 1.2 shall be deemed “Restricted Shares” and shall be sold to, and be repurchased by, the Company if any the conditions described
in this Section 1.1 has been satisfied (the “Sale Obligation”). 
 (B)    In
the event that the Principal voluntarily and unilaterally terminates his employment/service contract with any applicable Group Company or the Principal’s employment or service relationship is terminated by any applicable Group Company for Cause
(each, a “Termination”), unless otherwise approved by the board of directors of the Company (the “Board”) (which approval must include the approval of all of the directors of the Company appointed by any
holder of preferred shares of the Company (the “Preferred Directors”)), the Principal Holding Company(ies) shall, and the Principal shall ensure that the Principal Holding Company(ies) shall, sell to the Company, and the Company
shall repurchase from the Principal Holding Company(ies), all of the Restricted Shares at a price of US$0.0001 per share (as adjusted for share splits and similar transactions). For purposes of this Deed. 

(i)    “Cause” means any one of the following grounds: (i) an unauthorized use or disclosure
by the Principal of a Group Company’s confidential information or trade secrets, which result in a Material Adverse Effect, (ii) a material breach by the Principal of any employment-related agreement or other agreement between the
Principal and any Group Company, (iii) a material failure by the Principal to comply with any Group Company’s written policies or rules which results in a Material Adverse Effect, (iv) the Principal’s engagement in any criminal
conduct or fraud, (v) the Principal’s gross negligence or willful misconduct which results in a Material Adverse Effect, (vi) a continued failure or incompetence by the Principal to perform his core responsibilities which results in a
Material Adverse Effect. 
 (ii)    “Control” of a given entity means the power or authority,
whether exercised or not, to direct the business, management and policies of such entity, directly or indirectly, whether through the ownership of voting securities, by Contract or otherwise; provided, that such power or authority shall conclusively
be presumed to exist upon possession of beneficial ownership or power to direct the vote of more than fifty percent (50%) of the votes entitled to be cast at a meeting of the members or shareholders of such entity or power to control the composition
of a majority of the board of directors of such entity. The terms “Controlled” and “Controlling” have meanings correlative to the foregoing 

  
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 (iii)    “Group Company” means each of the Company
and any other entity directly or indirectly Controlled by the Company, and “Group” refers to all of the Group Companies collectively. 

(iv)    “Material Adverse Effect” means any event, occurrence, fact, condition, change or
development that has had, has, or could reasonably be expected to have, individually or together with other events, occurrences, facts, conditions, changes or developments, a material adverse effect on the business, properties, assets, employees,
operations, results of operations, condition (financial or otherwise), prospects, assets or liabilities of the Group, taken as a whole. 

1.2    Vesting. 

(A)    Unless otherwise approved by the Board (which approval must include the approvals of the Preferred Directors), the
Restricted Shares shall vest according to the schedule set forth in this Section 1.2. For purposes of this Deed, the “Vesting Commencement Date” shall be the date hereof. Fifty percent (50%) of the total Restricted
Shares held by the Principal through the Principal Holding Company(ies) shall become vested and shall no longer be deemed Restricted Shares at the end of each anniversary of continuous, full-time employment with the applicable Group Company
completed by the Principal starting from the Vesting Commencement Date, so that at the end of two (2) years of continuous, full-time employment with the applicable Group Company starting from the Vesting Commencement Date, the entirety of the
Restricted Shares held by the Principal through the Principal Holding Company(ies) shall have become vested and shall no longer be deemed Restricted Shares. 

Notwithstanding the foregoing, all the remaining Restricted Shares held by the Principal through the Principal Holding Company(ies)
shall vest immediately and no longer be deemed Restricted Shares upon a Deemed Liquidation Event or IPO of the Company. 

1.3    Mechanism of Repurchase. Within five (5) days after the occurrence of a Termination, the Principal
shall notify the Company and the Board of such Termination. Within ninety (90) days following a Termination with respect to the Principal (the “Repurchase Period”), the Principal and the Principal Holding Company(ies)
and the Company shall complete the repurchase of the Restricted Shares. At the Company’s option, the aggregate repurchase price of the Restricted Shares being repurchased may be paid: (i) by delivery with such notice of a check to the
Principal or his or her executor, or (ii) by cancellation by the Company of an amount of the Principal’s indebtedness to the Company, or (iii) by a combination of (i) and (ii) so that the combined payment and cancellation of
indebtedness equals such repurchase price. Upon the occurrence of a Termination and so long as the Company makes available payment of the repurchase price as provided herein, the repurchase shall be deemed completed, and the Restricted Shares being
repurchased and all rights and interests therein shall be canceled, and the Principal shall no longer be considered the owner of those Restricted Shares repurchased for record or any other purposes and will be entitled thereafter only to receipt of
the purchase price for the Restricted Shares repurchased. The Company shall update its register of members to reflect the above repurchase and cancel the portion of the repurchased Restricted Shares, within thirty (30) days after the Principal
or the Principal Holding Company(ies) receives the aggregate purchase price. 

  
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 2.    Prohibition on Transfer of Restricted Shares. 

2.1    Prohibition on Transfer. The Principal and Principal Holding Company(ies) shall not directly or indirectly
sell, assign, transfer, pledge, hypothecate, or otherwise encumber or dispose of in any way or otherwise grant any interest or right with respect to (“Transfer”) all or any part of any interest in any Restricted Shares. Any
Restricted Shares that have become vested shall be Transferred in accordance with the terms of this Deed, applicable Law and the Shareholders Agreement. Any attempt to Transfer the Restricted Shares in violation of this Deed or the Shareholders
Agreement shall be null and void, shall not be recorded on the register of members of the Company and shall not be recognized by the Company. 

2.2    No Indirect Transfers. Each of the Principal and Principal Holding Company(ies) further agrees not to
circumvent or otherwise avoid the transfer restrictions or intent thereof set forth in this Deed and the Shareholders Agreement by the direct or indirect holding of any Equity Securities of the Company through one or more entities in which interests
may be Transferred free of such restrictions. 
 3.    Additional Shares or Substituted Securities. In the event
of the declaration of a share dividend, the declaration of an extraordinary dividend payable in a form of Shares, a spin-off, a share split, an adjustment in conversion ratio, a recapitalization or a similar
transaction affecting the Company’s outstanding securities without receipt of consideration, the prohibition of transfer under this Section 3 and the Sale Obligation shall apply mutatis mutandis to any new,
substituted or additional securities or other property (including money paid other than as an ordinary cash dividend) that by reason of such transaction are distributed with respect to any Restricted Shares then subject to the Sale Obligation and
the prohibition of transfer, to the same extent as such Restricted Shares. 
 4.    Legends. The certificate or
certificates representing the Restricted Shares shall bear the following legends (as well as any legends required by the Shareholders Agreement, and any applicable securities Laws): 

THE SHARES REPRESENTED BY THIS CERTIFICATE MAY BE TRANSFERRED ONLY IN ACCORDANCE WITH THE TERMS OF THE SHARE RESTRICTION DEED AND THE
SHAREHOLDERS AGREEMENT BY AND AMONG THE HOLDER HEREOF, THE COMPANY, CERTAIN OTHER SHAREHOLDERS OF THE COMPANY AND CERTAIN OTHER PARTIES THERETO, RESPECTIVELY. COPIES OF SUCH DEED AND AGREEMENT ARE ON FILE WITH THE PRINCIPLE OFFICE OF THE COMPANY.

 5.    Miscellaneous.  

5.1    Severability. Whenever possible, each provision of this Deed shall be interpreted in such manner as to be
valid, legal, and enforceable under all applicable laws. If, however, any provision of this Deed shall be invalid, illegal, or unenforceable under any such applicable law in any jurisdiction, it shall, as to such jurisdiction, be deemed modified to
conform to the minimum requirements of such law, or, if for any reason it is not deemed so modified, it shall be invalid, illegal, or unenforceable only to the extent of such invalidity, illegality, or limitation on enforceability without affecting
the remaining provisions of this Deed, or the validity, legality, or enforceability of such provision in any other jurisdiction. 

  
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 5.2    Amendment; Waiver. This Deed may be amended, modified,
superseded, canceled, renewed or extended only by an Deed in writing executed by the Principal and the Company, provided that the Board (which approval must include the approvals of the Preferred Directors) approves such amendment. The failure by
any party at any time to require performance or compliance by the other of any of its obligations or agreements will in no way affect the right to require such performance or compliance at any time thereafter. The waiver by any party of a breach of
any provision of this Deed will not be treated as a waiver of any preceding or succeeding breach of such provision or as a waiver of the provision itself. No waiver of any kind will be effective or binding, unless it is in writing and is signed by
the party against whom such waiver is sought to be enforced. 
 5.3    Assignment. This Deed and the rights and
obligations of a party hereunder shall not otherwise be assigned without the consent of the other party. 

5.4    Governing law. This Deed shall be governed by and construed under the laws of Hong Kong Special
Administrative Region, without regard to the principles of conflicts of laws thereunder. 
 5.5    Dispute
Resolution. 
 (a)    Any dispute, controversy or claim (each, a “Dispute”) arising out of
or relating to this Deed, or the interpretation, breach, termination, validity or invalidity thereof, shall be referred to arbitration upon the demand of the claimant to the dispute with notice (the “Arbitration Notice”) to
the respondent(s) to the dispute. 
 (b)    The Dispute shall be settled by arbitration in Hong Kong by the Hong Kong
International Arbitration Centre (the “HKIAC”) in accordance with the Hong Kong International Arbitration Centre Administered Arbitration Rules (the “HKIAC Rules”) in force when the Arbitration Notice
is submitted in accordance with the HKIAC Rules. There shall be three (3) arbitrators. The claimant(s) to the dispute shall jointly select one arbitrator and the respondent(s) to the dispute shall jointly select one arbitrator. All selections
shall be made within 30 days after the selecting Party gives or receives the demand for arbitration. Such arbitrators shall be freely selected, and the Parties shall not be limited in their selection to any prescribed list. The Chairman of the HKIAC
shall select the third arbitrator, who shall be qualified to practice law in Hong Kong. 
 (c)    The arbitral
proceedings shall be conducted in English. To the extent that the HKIAC Rules are in conflict with the provisions of this Section, including the provisions concerning the appointment of the arbitrators, the provisions of this Section shall prevail.

 (d)    Each party to the arbitration shall cooperate with each other parties to the arbitration in making full
disclosure of and providing complete access to all information and documents requested by such other party in connection with such arbitral proceedings, subject only to any confidentiality obligations binding on such party. 

(e)    The award of the arbitral tribunal shall be final and binding upon the parties thereto, and the prevailing party
may apply to a court of competent jurisdiction for enforcement of such award. 
 (f)    The arbitral tribunal shall
decide any Dispute submitted by the parties to the arbitration strictly in accordance with the substantive Laws of Hong Kong, without regard to principles of conflict of laws thereunder, and shall not apply any other substantive Law. 

  
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 (g)    Any party to the Dispute shall be entitled to seek preliminary
injunctive relief from any court of competent jurisdiction pending the constitution of the arbitral tribunal. 

(h)    During the course of the arbitral tribunal’s adjudication of the Dispute, this Deed shall continue to
be performed except with respect to the part in dispute and under adjudication. 
 5.6    Specific Performance.
Each of the parties hereto recognizes and acknowledges that a breach by it of any covenants or agreements contained in this Deed will cause the other party to sustain damage for which it would not have an adequate remedy at law for money damages,
and therefore each of the parties hereto agrees that in the event of any such breach the aggrieved party shall be entitled to the remedy of specific performance of such covenants and agreements and injunctive and other equitable relief in addition
to any other remedy to which it may be entitled, at law or in equity. 
 5.7    Termination. This Deed will be
terminated and will be of no further force and effect upon a Deemed Liquidation Event or the IPO of the Company. 

5.8    Rights Cumulative. Each and all of the various rights, powers and remedies of a party hereto will be
considered to be cumulative with and in addition to any other rights, powers and remedies which such party may have at law or in equity in the event of the breach of any of the terms of this Deed. The exercise or partial exercise of any right, power
or remedy will neither constitute the exclusive election thereof nor the waiver of any other right, power or remedy available to such party. 

5.9    No Waiver. Failure to insist upon strict compliance with any of the terms, covenants, or conditions hereof
will not be deemed a waiver of such term, covenant, or condition, nor will any waiver or relinquishment of, or failure to insist upon strict compliance with, any right, power or remedy power hereunder at any one or more times be deemed a waiver or
relinquishment of such right, power or remedy at any other time or times. 
 5.10    No Presumption. The parties
acknowledge that any applicable law that would require interpretation of any claimed ambiguities in this Deed against the party that drafted it has no application and is expressly waived. If any claim is made by a party relating to any conflict,
omission or ambiguity in the provisions of this Deed, no presumption or burden of proof or persuasion will be implied because this Deed was prepared by or at the request of any party or its counsel. 

5.11    Headings. The headings used in this Deed are used for convenience only and are not to be considered in
construing or interpreting this Deed. 
 5.12    Counterparts. This Deed may be executed in two or more
counterparts, each of which shall be treated as an original, but all of which together shall constitute one and the same instrument. Any counterpart or other signature delivered by facsimile shall be deemed for all purposes as being good and valid
execution and delivery of this Deed by that party. 
 [The remainder of this page has been intentionally left blank.] 

  
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 IN WITNESS WHEREOF, the parties have executed this Deed as of the date first above written. 

COMPANY: 
  

							
	
EXECUTED and DELIVERED              
           
	  	 	)	 	  	
	 as a DEED by
	  	 	)	 	  	
	 QTECH LTD.
	  	 	)	 	  	
	in the presence of:	  	 	)	 	  	

  

	
	 
	Name:
	Title:

  

	
	 
	Signature of witness
	Name:
	Address:

 [Signature Page to Share Restriction Deed] 

 IN WITNESS WHEREOF, the parties have executed this Deed as of the date first above written. 

PRINCIPAL HOLDING COMPANY: 
  

							
	
SIGNED, SEALED and DELIVERED            
            
	  	 	)	 	  	
	 as a DEED by
	  	 	)	 	  	
	NEWS OPTIMIZER (BVI) LTD.	  	 	)	 	  	
	in the presence of	  	 	)	 	  	

  

	
	 
	Name:
	Title:

  

	
	 
	Signature of witness
	Name:
	Address

 [Signature Page to Share Restriction Deed] 

 IN WITNESS WHEREOF, the parties have executed this Deed as of the date first above written. 

PRINCIPAL: 
  

							
	
SIGNED, SEALED and DELIVERED            
             
	  	 	)	 	  	
	 as a DEED by
	  	 	)	 	  	
		  	 	)	 	  	
	in the presence of	  	 	)	 	  	

  

	
	 
	Signature of witness
	Name:
	Address

 [Signature Page to Share Restriction Deed]EX-10.1

 Exhibit 10.1 
  

			
		
	[***]	 	Text omitted and filed separately with the Securities and Exchange Commission/Confidential Treatment Requested under 17 C.F.R. Section 240.24b-2

 FOURTH AMENDMENT TO LEASE 

This Fourth Amendment to Lease (this “Fourth Amendment”) is made and entered into by and between PRII 355 ALHAMBRA CIRCLE,
LLC, a Delaware limited liability company (“Landlord”), as successor-in-interest to 355 Alhambra Plaza, Ltd., a Florida limited partnership
(“Original Landlord”) and to CPT 355 Alhambra Circle, LLC, a Delaware limited liability company (“Intermediate Landlord”), and CATALYST PHARMACEUTICALS, INC. (f/k/a Catalyst Pharmaceutical Partners, Inc.), a
Delaware corporation (“Tenant”), effective as of the date this Fourth Amendment is executed by Landlord, as evidenced on the signature page attached hereto (the “Effective Date”). 

W I T N E S S E T H 

WHEREAS, Original Landlord and Tenant previously entered into that certain Lease dated March 26, 2007 (the “Original
Lease”), as amended by (i) that certain Lease Addendum by and between Original Landlord and Tenant, dated June 5, 2007 (the “Addendum”), (ii) that certain First Amendment to Lease by and between Intermediate
Landlord and Tenant, dated June 30, 2011 (the “First Amendment”), (iii) that certain Second Amendment to Lease by and between Intermediate Landlord and Tenant, dated February 4, 2014 (the “Second
Amendment”), and (iii) that certain Third Amendment to Lease by and between Intermediate Landlord and Tenant, dated March 16, 2015 (the “Third Amendment;” the Original Lease, as so amended, being the
“Lease”), for the lease by Tenant of certain premises consisting of approximately 5,247 rentable square feet, designated as Suite 1250 (the “Existing Premises”), in the building located at 355 Alhambra Circle, Coral
Gables, Florida (the “Building”), all as more particularly described in the Lease; 
 WHEREAS, Landlord has succeeded to
all of the rights, interests and obligations of Original Landlord and Intermediate Landlord under the Lease; 
 WHEREAS, the Term of the
Lease is currently scheduled to expire on November 30, 2022, and the Relocation Date, as defined in the Third Amendment, occurred on August 19, 2015; and 

WHEREAS, Landlord and Tenant desire to amend the Lease to, among other things, expand the Premises (as such term is used in the Lease), and to
modify certain other terms and provisions of the Lease, all as more particularly provided below. 
 NOW, THEREFORE, for good and valuable
consideration, the receipt and sufficiency of which is hereby acknowledged, and pursuant to the foregoing, and in consideration of the mutual covenants and agreements contained in the Lease and herein, the Lease is hereby modified and amended as set
out below: 
 1.    Defined Terms. All capitalized terms used herein shall have the same meaning as defined in
the Lease, unless otherwise defined in this Fourth Amendment. 
 2.    Expansion of Premises. Effective upon the
earliest to occur of: (i) the date that the Expansion Improvements (as defined in Section 6 below) are substantially completed, or (ii) the date that the Expansion Improvements would have been substantially
completed except for Tenant-caused delays, or (iii) the date that Tenant, or any person occupying any of the Expansion Premises with Tenant’s permission, commences business operations from the Expansion Premises (such earliest date being
the “Expansion Date” and estimated to be August 1, 2018), the Premises shall be expanded to include that certain Suite 1500, which contains approximately 2,616 rentable square feet on the Fifteenth Floor of the Building, as
further depicted on Exhibit A attached hereto (the 

  
 1 

 
“Expansion Premises”), for a Term that is coterminous with the Lease Term (which is currently scheduled to expire on November 30, 2022) and which Expansion Premises shall be
leased by Tenant upon and subject to all of the existing terms and provisions of the Lease, except as otherwise amended herein. As of the Expansion Date, all references in the Lease to the “Premises” shall refer to both the Existing
Premises and the Expansion Premises and shall be stipulated to contain a total of 7,863 rentable square feet. Upon the Expansion Date, Landlord shall prepare and deliver to Tenant, an expansion commencement certificate which Tenant shall acknowledge
by executing a copy and returning it to Landlord. If Tenant fails to sign and return the expansion commencement certificate or provide to Landlord detailed comments thereto reasonably questioning the date set forth by Landlord within ten (10)
days of its receipt from Landlord, the expansion commencement certificate as sent by Landlord shall be deemed to have correctly set forth the Expansion Date and the other matters addressed in the expansion commencement certificate. Failure of
Landlord to send the expansion commencement certificate shall have no effect on the Expansion Date. 
 3.    Base
Rent. Tenant shall continue to pay Base Rent for the Existing Premises in accordance with the existing terms and provisions of the Lease applicable thereto. Commencing on the Expansion Date and continuing throughout the remainder of the Term,
Tenant shall also pay Base Rent for the Expansion Premises. Accordingly, the Base Rent payable for only the Expansion Premises (2,616 rsf) shall be as follows: 
  

											
	 Period
	 	
Annual Rate/RSF
	 	 Monthly Installments*

	 Expansion Date – August 31, 2018
	 	$[***]	 	$[***]
	 September 1, 2018 – August 31, 2019
	 	$[***]	 	$[***]
	 September 1, 2019 – August 31, 2020
	 	$[***]	 	$[***]
	 September 1, 2020 – August 31, 2021
	 	$[***]	 	$[***]
	 September 1, 2021 – August 31, 2022
	 	$[***]	 	$[***]
	 September 1, 2022 – November 30, 2022
	 	$[***]	 	$[***]

  

	*	 plus any sales, use or other applicable tax. 

	±	 Notwithstanding the foregoing, the Base Rent attributable to the Expansion Premises shall be abated for the
first sixty (60) days following the Expansion Date (such period, the “Abatement Period”; the abatement amount being estimated to be [***] per month the first month of such abatement and [***] for the second month of such
abatement, for an estimated total abatement of [***], subject to adjustment if the Expansion Date does not occur on August 1, 2018; the actual amount to be abated after the Expansion Date is determined being referred to herein, collectively, as
the “Abated Amount”); provided, however, that if at any time during the remaining Term of the Lease, Tenant fails to timely cure a monetary default under the Lease beyond any applicable notice and cure period, then, at
Landlord’s option (exercised in Landlord’s sole and absolute discretion), the unamortized portion of the Abated Amount (amortized on a straight-line basis over the Term of the Lease following the Expansion Date) shall immediately become
null and void and such unamortized portion of the Abated Amount shall become immediately due and payable to Landlord. The abatement of Base Rent attributable to the Expansion Premises provided during the Abatement Period shall not relieve Tenant
from the performance of Tenant’s other obligations under the Lease, including, without limitation, the obligation to pay in full and on a timely basis all other charges, including Tenant’s Proportionate Share of Increased Operating Costs
and all rent for the Existing Premises. 

  

	[***]	 Confidential Treatment Requested 

  
 2 

 4.    Additional Rent. Tenant shall continue to pay all items of
Additional Rent, including, without limitation, Tenant’s Proportionate Share of Increased Operating Costs, in accordance with the existing terms and conditions of the Lease, including, without limitation, Section 7 of
the Third Amendment. Commencing on the Expansion Date and continuing thereafter for the remainder of the Term, Tenant shall also pay Additional Rent with respect to the Expansion Premises, including, without limitation, Tenant’s Proportionate
Share of Increased Operating Costs; provided, however, (i) Tenant’s Proportionate Share for the Expansion Premises shall be deemed to be 1.1666% (2,616 rsf / 224,241 rsf), and (ii) the “Base Year” solely with respect to the
Expansion Premises shall be the calendar year 2019 (it being understood that Tenant’s obligations with respect to Tenant’s Proportionate Share of Increased Operating Costs attributable solely to the Expansion Premises shall not commence
until January 1, 2020). 
 5.    Parking. In connection with the Expansion Premises, Tenant shall be
entitled to an additional eight (8) unreserved parking spaces. Tenant shall pay for each such parking space in accordance with the terms set forth in Section 10 of the Third Amendment. Tenant shall, in addition, be
permitted additional parking spaces, subject to availability (as determined by Landlord), on a month to month basis, and Tenant shall pay Landlord the prevailing monthly rates (plus applicable taxes) for such additional parking spaces. 

6.    Condition of the Premises. Tenant is currently in possession of the Existing Premises, and, as of the
Expansion Date, agrees to accept from Landlord through the expiration of the Term, the Expansion Premises in its existing “AS-IS,” “WHERE-IS,” and
“WITH ALL FAULTS” condition and, subject to any of Landlord’s existing obligations to maintain and repair the Building that are currently set forth in the lease, Landlord shall have no obligation whatsoever to refurbish the Existing
Premises or Expansion Premises at any time through the expiration of the Term; provided, however, Landlord shall, at Landlord’s sole cost and expense, (i) install new Building-standard carpet in the Expansion Premises, and
(ii) repaint the Expansion Premises using Building-standard paint ((i) and (ii), collectively, the “Expansion Improvements”). Tenant acknowledges and agrees that any obligations of Landlord originally existing in the Lease to
complete leasehold improvements or furnish allowance, if any, have been completed and satisfied in their entirety, including, without limitation, as set forth in Section 23 of the Lease Summary of the Original Lease,
Exhibit D of the Original Lease, Section 2 of the Addendum, Exhibit B to the First Amendment, in Exhibit B to the Second Amendment, and Exhibit B to the Third Amendment. 

7.    Insurance. Section 6.1(c) of the Original Lease is amended to require Tenant to
maintain umbrella/excess liability coverage of at least $5 million. On all insurance to be required to be carried by Tenant under the Lease, Tenant shall name, as additional insureds, Landlord (PRII 355 Alhambra Circle, LLC), Landlord’s
property manager, Landlord’s mortgagee, and the Landlord Entities (defined in Section 11 below), subject to the requirement that Landlord provide Tenant with written notice of the identity of such additional insureds
to the extent that they are not named in this Fourth Amendment. 
 8.    Preferential Rights or Options.
Notwithstanding anything contained in the Lease to the contrary, Landlord and Tenant stipulate and agree that, except for the Termination Option set forth in Section 12 of the Third Amendment and the renewal option in
Section 14 of the Third Amendment, Tenant has no preferential rights or options under the Lease, as herein amended, such as any rights of renewal, expansion, reduction, refusal, offer, purchase, termination, relocation or
any other such preferential rights or options, such rights originally set forth in the Lease being 

  
 3 

 
hereby null and void in their entirety and of no further force or effect. The Termination Payment (as defined in Section 12 of the Third Amendment) shall be increased to
include both (i) the Leasing Costs related to the Third Amendment, as defined and calculated in Section 12 of the Third Amendment, and (ii) the “Fourth Amendment Leasing Costs,” which shall be defined as
the “worth at the time of the termination” of (a) the brokerage commissions paid by Landlord in connection with this Fourth Amendment in accordance with Section 10 of this Fourth Amendment, and (b) the
cost of the Expansion Improvements paid by Landlord. For purposes of this Section, the “worth at the time of the termination” is computed by amortizing the Fourth Amendment Leasing Costs over the period from the Expansion Date through
November 30, 2022 at an interest rate of eight percent (8%) per annum to determine the portion allocated to the period after the Early Termination Date. Accordingly, the [***] limit set forth in Section 12 of the Third
Amendment shall be increased to include the Fourth Amendment Leasing Costs, estimated to be [***] if the cost of the Expansion Improvements is [***] per rsf and the Expansion Date is September 1, 2018. Landlord shall provide Tenant with the
amount and its calculation of the Termination Payment (including reasonable detail with respect to payments for the Expansion Improvements) within thirty (30) days following the date Tenant sends Landlord a written request therefor. 

9.    Landlord’s Address. Landlord’s notice address for all notices to be delivered under the Lease,
originally set forth in Section 3 of the Lease Summary of the Original Lease, is hereby amended to be as follows (or to such other address that Landlord may later designate in writing):. 

PRII 355 Alhambra Circle, LLC 

c/o PGIM Real Estate 

7 Giralda Farms 

Madison, NJ 07940 

Attention: PRISA II Asset Manager 

With a copy to: 

PRII 355 Alhambra Circle, LLC 

c/o PGIM Real Estate 

7 Giralda Farms 

Madison, NJ 07940 

Attention: Legal 

And 

PRII 355 Alhambra Circle, LLC 

c/o Cushman & Wakefield 

355 Alhambra Circle, Suite 1520 

Coral Gables, Florida 33134 

Attention: Property Manager 

10.    Broker. Tenant warrants that it has had no dealings with any broker or agent other than Cushman &
Wakefield and Jones Lang LaSalle (collectively, the “Brokers”) in connection with the negotiation or execution of this Fourth Amendment, and Tenant agrees to indemnify Landlord and hold Landlord harmless from and against any and all
costs, expenses or liability for commissions or other compensations or charges claimed by any broker or agent, other than Brokers, with respect to this Fourth Amendment. 
  

	[***]	 Confidential Treatment Requested 

 

  
 4 

 11.    ERISA. Tenant represents, warrants and covenants to
Landlord that, as of the Effective Date and throughout the Term of the Lease, Tenant is not, and is not entering into the Lease on behalf of, (i) an employee benefit plan, (ii) a trust holding assets of such a plan or (iii) an entity
holding assets of such a plan. Notwithstanding any terms to the contrary in this Fourth Amendment, in no event may Tenant assign or transfer its interest under the Lease to a third party who is, or is entering into the Lease on behalf of,
(i) an employee benefit plan, (ii) a trust holding assets of such a plan or (iii) an entity holding assets of such a plan if such transfer would could cause Landlord to incur any prohibited transaction excise tax penalties or other
materially adverse consequences under the Employee Retirement Income Security Act of 1974, as amended, Section 4975 of the Internal Revenue Code of 1986, as amended or similar law. The representations, warranties, covenants and agreements set
forth in this Section are intended to inure to the benefit of both Landlord and the Landlord Entities and the Landlord Entities shall be entitled to rely hereon and enforce the provisions of this Section. Tenant acknowledges and agrees that as a
condition to the effectiveness of any assignment of, or sublease under, the Lease, and as a requirement and condition of the effectiveness of any consent to assignment or sublease by Landlord pursuant to the Lease, Tenant shall cause the assignee or
sublessee to reaffirm, on behalf of such assignee or sublessee, the representations of this Section 11 and Section 12 below, and it shall be reasonable for Landlord to refuse to consent to an
assignment of the Lease or sublease of the Premises in the absence of such reaffirmation. The “Landlord Entities” shall mean, collectively, The Prudential Insurance Company of America; PGIM, Inc.; PRISA II LHC, LLC; and any
designated affiliates of the foregoing, and any other legal or d/b/a name under which foregoing entities do business from time-to-time. 

12.    OFAC Compliance. Tenant certifies, represents, warrants and covenants to Landlord and the Landlord Entities
that: (i) it is not, and shall not during the Term become, a person or entity with whom Landlord is restricted from doing business under the Uniting and Strengthening America by Providing Appropriate Tools Required to Intercept and Obstruct
Terrorism Act of 2001, H. R. 3162, Public Law 107-56 (commonly known as the “USA Patriot Act”) and Executive Order Number 13224 on Terrorism Financing, effective September 24, 2001 and
regulations promulgated pursuant thereto (collectively, “Anti-Terrorism Laws”), including, without limitation, persons and entities named on the Office of Foreign Assets Control Specially Designated Nationals and Blocked Persons
List (collectively, “Prohibited Persons”); (ii) to the best of its knowledge, it is not currently engaged in any transactions or dealings with, or otherwise associated with, any Prohibited Persons, nor otherwise engaged in any
activity that would violate Anti-Terrorism Laws in connection with the use or occupancy of the Premises or the Building; (iii) it will not, during the Term, engage in any transactions or dealings with, or be otherwise associated with, any
Prohibited Persons, nor will it engage in any other activity that would violate Anti-Terrorism Laws in connection with the use or occupancy of the Premises or the Building; (iv) if at any time after the date hereof it becomes a Prohibited
Person, then it shall notify Landlord within five (5) business days after becoming aware of such designation; (v) if it breaches any representation or covenant set forth in this paragraph, or it hereafter becomes a Prohibited Person, then
in any such event, same shall constitute an event of default hereunder, entitling Landlord to any and all remedies under the Lease or at law or in equity (including the right to terminate the Lease), without affording the defaulting party any notice
or cure period; and (vi) it hereby agrees to defend (with counsel reasonably acceptable to Landlord), indemnify, and hold harmless Landlord and the Landlord Entities from and against any and all claims arising from or related to any such breach
of the foregoing certifications, representations, warranties and covenants. 
 13.    Entire Agreement/Conflict.
The transmission of this document by Landlord does not constitute an offer by Landlord and shall not be binding on Landlord until its execution by Landlord. The Lease, as amended by this Fourth Amendment, sets forth the entire agreement

  
 5 

 
between the parties with respect to the matters set forth herein and any exhibits, schedules and appendixes attached to this Fourth Amendment are incorporated herein as if fully set forth in this
Fourth Amendment and shall be deemed to be a part of this Fourth Amendment. There have been no additional oral or written representations or agreements. With the exception of those terms and conditions specifically modified and amended herein, the
herein referenced Lease shall remain in full force and effect in accordance with all its terms and conditions; however, Tenant shall not be entitled, in connection with entering into this Fourth Amendment, to any free rent, allowance, alteration,
improvement or similar economic incentive to which Tenant may have been entitled in connection with entering into the Lease, except as otherwise may be expressly provided in this Fourth Amendment. In the event of any conflict between the terms and
provisions of this Fourth Amendment and the terms and provisions of the Lease, the terms and provisions of this Fourth Amendment shall supersede and control. 

14.    Miscellaneous. This Fourth Amendment shall be construed and enforced in accordance with the laws of the
state in which the Premises are located. Time is of the essence with respect to all of Tenant’s obligations and deadlines set forth in this Fourth Amendment. No provision of this Fourth Amendment may be amended or added to except by an
agreement in writing signed by the parties hereto or their respective successors in interest. The illegality, invalidity or unenforceability of any provision of this Fourth Amendment shall in no way impair or invalidate any other provision of this
Fourth Amendment, and such remaining provisions shall remain in full force and effect. If two or more parties shall sign this Fourth Amendment as Tenant, the liability of each such party shall be deemed to be joint and several, and if the Tenant
consists of multiple parties, then any act of or notice from, or notice or refund to, or the signature of any one or more of them, with respect to the tenancy of the Lease, shall be binding upon each and all of them as Tenant with the same force as
if each and all of them had so acted, so given or received such notice or refund, or so signed. 
 15.    Joint
Product/Headings. This Fourth Amendment is the result of arms-length negotiations between Landlord and Tenant, both of whom were represented by their respective attorneys. Accordingly, neither party shall be deemed to be the author of this
Fourth Amendment and this Fourth Amendment shall not be construed against either party. The section and paragraph headings of this Fourth Amendment are for convenience only and in no way limit or enlarge the scope or meaning of the language hereof.

 16.    Counterparts. This Fourth Amendment may be executed in any number of counterparts, each of which shall
be deemed an original, and all of such counterparts shall constitute one agreement. To facilitate execution of this Fourth Amendment, the parties may execute such counterparts and exchange copies of such executed counterparts via telefax or e-mail, and such telefaxed or e-mailed copies shall serve as originals. 

17.    Authority. Each signatory of this Fourth Amendment for Tenant hereby represents that he or she has the
authority to execute and deliver the same on behalf of Tenant. 
 [Signature Page Follows] 

  
 6 

 1.    IN WITNESS WHEREOF, the parties hereto have executed this Fourth
Amendment to be effective as of the Effective Date. 
  

											
	Witnesses:	  		 		 	LANDLORD
			
	/s/ Ryan Smith	 		 	 PRII 355 ALHAMBRA CIRCLE, LLC,

a Delaware limited liability company

	Print Name	  	Ryan Smith	 	
				
	/s/ Chris Bell	 		 	By:	 	 PRISA II LHC, LLC, a Delaware limited

liability company, its sole member

	Print Name	  	Chris Bell	 		 		 		 	
		  		 		 		 	By:	 	/s/ Amy Ziegler
		  		 		 		 	Name:	 	Amy Ziegler
		  		 		 		 	Title:	 	Vice President
		  		 		 		 	Date:	 	8/13/18
				
		  		 		 	TENANT
				
	Witnesses:	  		 		 	 CATALYST PHARMACEUTICALS, INC.

(f/k/a Catalyst Pharmaceutical Partners, Inc.), a Delaware corporation

	/s/ Isabel Nunez	 	
	Print Name	  	Isabel Nunez	 		 		 		 	
					
	/s/ Ismaris Bouchard	 		 		 	By:	 	/s/ Patrick J. McEnany
	Print Name	  	Ismaris Bouchard	 		 		 	Name:	 	Patrick J. McEnany
		  		 		 		 	Title:	 	CEO
		  		 		 		 	Date:	 	8/8/18

 [End of Signatures] 

  
 7 

 EXHIBIT A 

EXPANSION PREMISES 
 [***]

  

	[***]	 Confidential Treatment Requested 

 

  
 8

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