Document:

FORM
OF

     

    0%
SENIOR SUBORDINATED CONVERTIBLE PROMISSORY NOTE

     

    THIS
PROMISSORY NOTE AND THE SECURITIES OBTAINABLE UPON CONVERSION HEREOF HAVE NOT
BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (“THE ACT”), OR THE
SECURITIES LAWS OF ANY STATE.  THE SECURITIES MAY NOT BE TRANSFERRED
EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT UNDER SUCH ACT AND
APPLICABLE STATE SECURITIES LAWS OR PURSUANT TO AN APPLICABLE EXEMPTION FROM OR
IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION REQUIREMENTS OF THE ACT AND IN
ACCORDANCE WITH APPLICABLE STATE SECURITIES LAWS AS EVIDENCED BY A LEGAL OPINION
OF COUNSEL TO THE TRANSFEROR TO SUCH EFFECT, THE SUBSTANCE OF WHICH SHALL BE
REASONABLY ACCEPTABLE TO THE COMPANY.

     

    
      0% SENIOR
SUBORDINATED CONVERTIBLE PROMISSORY NOTE

    

     

    
      	
              No.
      SPN-[   ]

            	
              ______
      __, 2009

            
	
              U.S.
      $ _____________

            	 
      

    

    

    FOR VALUE
RECEIVED, the undersigned, Vyteris, Inc., a Nevada corporation (the “Company”),
hereby unconditionally promises to pay, in accordance with the Subscription
Agreement (the “Subscription Agreement”), dated as of the date hereof, by and
between the Company and ____________________ (the “Purchaser”), on the Maturity
Date (as defined in Section 1 hereof) to
the order of the Purchaser, in lawful money of the United States of America and
in immediately available funds, the principal amount of _____________________
($________) Dollars (the “Principal Amount”).  No interest shall
accrue or shall be payable under this Note.

     

    This Note
is the promissory note referred to in the Subscription Agreement and the
Security Agreement (as hereinafter defined), and is entitled to the benefits
thereof, is secured as provided in the Security Agreement and is subject to
conversion as set forth herein.  This Note, and all representations,
warranties, covenants and agreements contained herein, and in the Subscription
Agreement and the Security Agreement, shall be binding upon the Company and its
successors and permitted assigns and shall inure to the benefit of the Purchaser
and its successors and assigns.  The Company may not assign or
delegate any of its duties or obligations under this Note without the written
consent of the Purchaser.

     

    This Note
is one of a series of 0% senior subordinated convertible promissory notes of
like tenor and ranking made by the Company in favor of certain investors and
issued, from time to time (collectively, the “Notes”), all upon terms set forth
in that certain Confidential Private Placement Memorandum, dated November 4,
2009, as same may be amended or supplemented from time to time (collectively
referred to herein as the “Memorandum”).  Each of the Notes shall rank
equally without preference or priority of any kind over one another, and all
payments on account of principal and interest with respect to any of the Notes
shall be applied ratably and proportionately on the outstanding Notes on the
basis of the principal amount of the outstanding indebtedness represented
thereby.

     

    
      
        
        

      

      
        B-1

        
          

        

      

      
        
        

      

       

    

    By its
execution of the Subscription Agreement in the form attached to the Memorandum
as Annex D, the
Purchaser has authorized Collateral Agents, LLC, a New York limited liability
company, to act as collateral agent (the “Collateral Agent”) on behalf of the
Purchaser and other purchasers of the Notes, and in such capacity to enter into
the Security Agreement in the form attached to the Memorandum as Annex C, as the same
may be amended, modified, restated or supplemented from time to time (the
“Security Agreement”), and to exercise for the benefit of the Purchaser all
rights, powers and remedies provided to it, under or pursuant to the Security
Agreement including, without limitation, those available upon an Event of
Default (as defined in Section 8 hereof),
subject always to the terms, conditions, limitations and restrictions provided
in the Security Agreement.

    

    1.         
Maturity.  Unless
otherwise converted into common stock of the Company, par value $.015 per share
(“Common Stock”), in accordance with the Section 5 hereof,
this Note shall mature on __________, 20121,
unless such date shall be otherwise extended in writing by the Purchaser (such
date, the “Maturity Date”).  On the Maturity Date, unless, and to the
extent, converted into shares of Common Stock in accordance with the provisions
hereof, any and all outstanding principal due and owing under the Note shall be
immediately paid by the Company.

     

    2.         
Senior. Except with
respect to indebtedness of up to $3.3 million owed to Ferring Pharmaceuticals,
Inc. and its related lien on the assets of the Company pursuant to that certain
security agreement between the Company and Ferring Pharmaceuticals, Inc., dated
March __, 2009 (the “Ferring Debt”), the indebtedness evidenced by this Note and
the payment of the Principal Amount shall be Senior (as hereinafter defined) to,
and have priority in right of payment over, all indebtedness for borrowed money
(except for other Notes) of the Company. “Senior” shall be deemed to mean that,
in the event of any default in the payment of the obligations represented by
this Note or of any liquidation, insolvency, bankruptcy, reorganization, or
similar proceedings relating to the Company, all sums payable on this Note,
shall first be paid in full, before any payment is made upon any other
indebtedness, now outstanding or hereinafter incurred (except for the Ferring
Debt), and, in any such event, any payment or distribution of any character
which shall be made in respect of any other indebtedness of the Company, shall
be paid over to the holder of this Note for application to the payment hereof,
unless and until the obligations under this Note (which shall mean the Principal
Amount and other obligations arising out of, premium, if any, and any costs and
expenses payable under, this Note) shall have been paid and satisfied in
full.

     

    3.   Affirmative
Covenants.  The Company covenants and agrees that, while any
amounts under this Note are outstanding, it shall:

     

    _________________________

    1 
Such date shall be inserted at
closing and shall be three years from the initial closing
date.

    
       

    

    
      
        
        

      

      
        B-2

        
          

        

      

      
        
        

      

       

    

     (a)   Do all
things necessary to preserve and keep in full force and effect its corporate
existence, including, without limitation, all licenses or similar qualifications
required by it to engage in its business in all jurisdictions in which it is at
the time so engaged; and continue to engage in business of the same general type
as conducted as of the date hereof; and continue to conduct its business
substantially as now conducted or as otherwise permitted hereunder;

     

     (b)   Pay and
discharge promptly when due all taxes, assessments and governmental charges or
levies imposed upon it or upon its income or profits or in respect of its
property before the same shall become delinquent or in default, which, if
unpaid, might reasonably be expected to give rise to liens or charges upon such
properties or any part thereof, unless, in each case, the validity or amount
thereof is being contested in good faith by appropriate proceedings and the
Company has maintained adequate reserves with respect thereto in accordance with
GAAP;

     

     (c)           Comply in
all material respects with all federal, state and local laws and regulations,
orders, judgments, decrees, injunctions, rules, regulations, permits, licenses,
authorizations and requirements applicable to it (collectively, “Requirements”)
of all governmental bodies, departments, commissions, boards, companies or
associations insuring the premises, courts, authorities, officials or officers
which are applicable to the Company or any of its properties, except where the
failure to so comply would not have a Material Adverse Effect (as defined in
this Section
3);

     

      (d)          Keep
proper records and books of account with respect to its business activities, in
which proper entries, reflecting all of their financial transactions, are made
in accordance with GAAP;

     

      (e)          Keep all
of its properties adequately insured at all times with responsible insurance
carriers against loss or damage by fire and other hazards, and maintain adequate
insurance at all times with responsible insurance carriers against liability on
account of damage or injury to persons and property; and

     

      (f)           Reserve
and keep available out of its authorized and unissued Common
Stock (as defined below) solely for the purpose of issuance
upon conversion of this Note as herein provided, free from preemptive rights or
any other actual contingent purchase rights of persons other than the Holder, such number of shares of Common Stock as
shall be issuable (taking into account the adjustments and restrictions of Section 6
hereof) upon the conversion of the aggregate principal amount of this Note.

     

    For
purposes hereof, “Material Adverse Effect” shall an event, matter, condition or
circumstance which has or would reasonably be expected to have a material
adverse effect on the business, operations, economic performance, assets,
financial condition, material agreements or results of operations of the Company
and its wholly owned subsidiary, Vyteris, Inc., a Delaware corporation,
considered as a whole.

    

    4.           
Negative
Covenants.  The Company covenants and agrees that while any
amount of this Note is outstanding it will not directly or
indirectly:

     

    
      
        
        

      

      
        B-3

        
          

        

      

      
        
        

      

       

    

    (a)          
Incur,
guarantee, assume or otherwise become responsible for (directly or indirectly)
any indebtedness for borrowed money (except for other Notes) that is senior or
pari passu to the Notes, without the prior written consent of the holders of
more than fifty percent (50%) of the outstanding principal of the Notes (the
“Requisite Consent”);

     

    (b)         
Create,
incur, assume or permit to exist any lien on any property or assets now owned or
hereafter acquired by it or on any income or revenues or rights in respect of
any thereof

     

    (c)          
Declare
or pay, directly and indirectly, any dividends or make any distributions,
whether in cash, property, securities or a combination thereof, with respect to
(whether by reduction of capital or otherwise) any shares of its capital stock
(including without limitation any preferred stock) or directly or indirectly
redeem, purchase, retire or otherwise acquire for value any shares of any class
of its capital stock or any option, warrant or other right to purchase or
acquire any such shares (in each case other than repurchases from terminated
employees of the Company) or set aside any amount for any such purpose;
or

     

    (d)          
Sell,
transfer, discount or otherwise dispose of any claim or debt owing to it,
including, without limitation, any notes, accounts receivable or other rights to
receive payment, except for reasonable consideration and in the ordinary course
of business.

     

    5.           
Conversion.

     

    (a)           Conversion Price and
Optional Conversion.  The Holder shall have the right, at its
option, to convert all or a portion of the Principal Amount of this Note into
shares of the Company’s Common Stock at a conversion price equal to $___ per
share1,
subject to adjustment as set forth in Section 6) (the
“Conversion
Price”).  The Holder shall exercise its right to convert this
Note by delivering to the Company a written notice setting forth its election to
convert (a “Written
Election to Convert”) in the form attached hereto as Exhibit A and
surrendering this Note.  Upon receipt of the Written Election to
Convert and the surrender of this Note, the Company shall issue and cause to be
delivered with all reasonable dispatch to or upon the written order of the
Holder, and in such name or names as the Holder may designate, a certificate or
certificates for the full number of shares of Common Stock so purchased upon
conversion of this Note.  Such certificate or certificates shall be
deemed to have been issued and any person so designated to be named therein
shall be deemed to have become a holder of record of such securities as of the
date of delivery of the Election to Convert, notwithstanding that the
certificate or certificates representing such securities shall not actually have
been delivered or that the stock transfer books of the Company shall then be
closed.  In the event that the Principal Amount of this Note exceeds
the amount being converted, the Company shall, upon such conversion execute and
deliver to the Holder a new Note for the Principal Amount of this Note
surrendered which is not being converted.

    __________________________

    
       

      1 
Such conversion price shall be inserted at closing and shall be
the lower of (i) $0.20 or (ii) average VWAP during the 10 trading days prior to
the applicable closing date.

    

     

    
      
        
        

      

      
        B-4

        
          

        

      

      
        
        

      

       

    

    (b)           Automatic
Conversion.  If any time prior to the Maturity Date, the
closing bid price of the Company Company’s Common Stock reaches or exceeds 300%
of the then applicable Conversion Price for twenty consecutive trading days, the
entire Principal Amount owing on this Note shall, without any action taken on
the part of the Purchaser, automatically convert into shares of the Company’s
Common Stock at a price equal to the then effective Conversion Price (the date
such contingency event is met hereinafter the “Effective Automatic Conversion
Date”).  The Company will promptly send written notice to the Holder
of this automatic conversion event and shall promptly (but in no event later
than ten trading days after the Effective Automatic Conversion Date) issue or
cause to be issued and cause to be delivered to the Purchaser, a certificate for
the Common Stock.  The Purchaser shall be deemed to have become holder
of record of such Common Stock as of the Effective Automatic Conversion
Date.

     

    (c)           Fractional
Shares.  No fractional shares of the Common Stock shall be
issued upon conversion of the Note.  In lieu of any fractional shares
to which the Purchaser would otherwise be entitled, the Company shall round up
as nearly as practicable to the nearest whole the number of shares of Common
Stock to be issued.

     

    6.            Adjustments.

     

                   (a)          Stock Dividends and
Splits. If the Company, at any time while this Note is outstanding: (A)
pays a stock dividend or otherwise make a distribution or distributions on
shares of its Common Stock or any other equity or equity equivalent securities
payable in shares of Common Stock, (B) subdivides outstanding shares of Common
Stock into a larger number of shares, (C) combines (including by way of reverse
stock split) outstanding shares of Common Stock into a smaller number of shares,
or (D) issues by reclassification of shares of the Common Stock any shares of
capital stock of the Company, then in each case the Conversion Price shall be
multiplied by a fraction of which the numerator shall be the number of shares of
Common Stock (excluding treasury shares, if any) outstanding immediately before
such event and of which the denominator shall be the number of shares of Common
Stock outstanding immediately after such event and the number of shares issuable
upon conversion of this Note shall be proportionately adjusted.  Any
adjustment made pursuant to this Section 6(a) shall
become effective immediately after the record date for the determination of
stockholders entitled to receive such dividend or distribution and shall become
effective immediately after the effective date in the case of a subdivision,
combination or re-classification.

     

    (b)           Additional Issuances of
Equity Securities.  If the Company, at any time while this Note
is outstanding, shall issue or sell any Equity Securities (as defined below) at
an effective price per share less than the then effective Conversion Price (such
lower price, the “Base
Share Price” and such issuances collectively, a “Dilutive
Issuance”), as adjusted hereunder (if the holder of the Equity Securities
so issued shall at any time, whether by operation of purchase price adjustments,
reset provisions, conversion, floating conversion, exercise or exchange prices
or otherwise, or due to warrants, options or rights per share which is issued in
connection with such issuance, be entitled to receive shares of Common Stock at
an effective price per share which is less than the  then effective
Conversion Price, such issuance shall be deemed to have occurred for less than
the then effective Conversion Price on such date of the Dilutive Issuance),
then, the Conversion Price shall be reduced and only reduced to equal the Base
Share Price.  Notwithstanding the foregoing, no adjustments shall be
made, paid or issued under this Section 6(b) in
respect of Exempt Issuances (as defined below).  The Company shall
notify the Holder in writing as promptly as reasonably possible following the
issuance of any Equity Securities subject to this section, indicating therein
the applicable issuance price, or of applicable reset price, exchange price,
conversion price and other pricing terms (such notice the “Dilutive
Issuance Notice”).  For purposes of clarification, whether or
not the Company provides a Dilutive Issuance Notice pursuant to this Section 6(b), upon
the occurrence of any Dilutive Issuance while this Note is outstanding, after
the date of such Dilutive Issuance the Holder is entitled to the Base Share
Price regardless of whether the Holder accurately refers to the Base Share Price
in the Written Election to Convert.

     

    
      
        
        

      

      
        B-5

        
          

        

      

      
        
        

      

       

    

    For purposes of this Section 6(b), the
following definitions shall apply:

     

    “Common
Stock Equivalents” means any securities of the Company or its
subsidiaries which would entitle the holder thereof to acquire at any time
Common Stock, including, without limitation, any debt, preferred stock, rights,
options, warrants or other instrument that is at any time convertible into or
exercisable or exchangeable for, or otherwise entitles the holder thereof to
receive, Common Stock.

     

    “Equity
Securities” means (i) Common Stock and (ii) Common Stock
Equivalents, including, but not limited to, Notes issued subsequent to the date
of this Note.

    

    “Exempt
Issuance” means (i) any Equity Securities issued or issuable pursuant to
options, warrants or other rights issued or issuable to employees, officers or
directors of, or consultants or advisors to the Company or any subsidiary,
pursuant to equity incentive plans or other employee benefit arrangements; (ii)
any Equity Securities issued or issuable pursuant to any rights or agreements,
options, warrants or convertible securities outstanding as of the issuance date
of this Note; (iii) any Equity Securities issued or issuable for consideration
other than cash pursuant to a merger, consolidation, strategic alliance,
acquisition or similar business combination; (iv) any Equity Securities issued
or issuable in connection with any stock split, stock dividend, distribution or
recapitalization by the Company; (v) any Equity Securities issued or issuable
pursuant to any equipment loan or leasing arrangement, real property leasing
arrangement, or debt financing from a bank or similar financial or lending
institution; (vi) any Equity Securities issued or issuable to the Placement
Agent or its affiliates in connection with the offering of Notes pursuant to the
Memorandum; and (v) any Equity Securities issued to the Holder pursuant to the
Subscription Agreement, dated as of the date hereof, between the Company and the
Holder.  For clarification purposes, Notes that are issued pursuant to
the Memorandum at closings subsequent to the closing in which this Note has been
issued shall not be deemed to be
an Exempt Issuance hereunder.

    

    (c)           Mergers, Consolidations,
Etc. In the event of any consolidation or merger of Company with or into
another corporation or the conveyance of all or substantially all of the assets
of Company to another corporation or entity, this Note shall thereafter be
convertible into the number of shares of capital stock or other securities or
property to which a holder of the number of Common Stock deliverable upon
conversion hereof would have been entitled upon such consolidation, merger or
conveyance; and, in any such case, appropriate adjustment shall be made in the
application of the provisions herein set forth with respect to the rights and
interest of Holder thereafter, to the end that the provisions set forth herein
(including provisions with respect to adjustments in the Conversion Price) shall
thereafter be applicable, as nearly as may be practicable, in relation to any
shares of stock or other property thereafter deliverable upon the conversion
hereof.

     

    
      
        
        

      

      
        B-6

        
          

        

      

      
        
        

      

       

    

    (d)           Three Month Automatic
Adjustment.  The Conversion Price shall automatically be
reduced by 1.5% of the initial Conversion Price as set forth in Section 5(a) hereto
at the end of each ninety (90) day period following the issuance date hereof and
through the earlier of the Maturity Date or the date that all principal
hereunder shall have been converted to Common Stock.   The
foregoing adjustment shall take place irrespective of any other adjustments that
may have occurred hereunder.

    

     (e)           Calculations. All
calculations under this Section 6 shall be
made to the nearest cent or the nearest 1/100th of a share, as the case may be.
For purposes of this Section 6, the number
of shares of Common Stock deemed to be issued and outstanding as of a given date
shall be the sum of the number of shares of Common Stock (excluding treasury
shares, if any) issued and outstanding.

    

    (f)           Voluntary Adjustment By
Company. The provisions of this Section 6 shall similarly
apply to successive, stock dividends, stock spits or combinations,
reclassifications, exchanges, substitutions, Dilutive Issuances or other
events.

    

    7.           Security
Interest.  This Note shall be secured by the assets of the
Company as set forth in the Security Agreement.

    

    8.           Events of
Default.  Subject to the terms of the Security Agreement, the
entire unpaid Principal Amount under this Note shall, at the option of the
Collateral Agent, acting on behalf of the Purchaser and the other purchasers of
the Notes, exercised by written notice to the Company, forthwith become and be
due and payable, without presentment, demand, protest or other notice of any
kind, all of which are hereby expressly waived, if any one or more of the
following events (herein called “Events of Default”) shall have occurred (for
any reason whatsoever and whether such happening shall be voluntary or
involuntary or come about or be effected by operation of law or pursuant to or
in compliance with any judgment, decree or order of any court or any order, rule
or regulation of any administrative or governmental body) and be continuing at
the time of such notice, that is to say:

    

    (a)           a
material breach by the Company of the Security Agreement;

     

    (b)           the
Company shall default in the performance of, or violate any of the covenants and
agreements contained in this Note or the Security Agreement, including without
limitation, the failure to pay amounts due under this Note on its Maturity Date,
or any of the other Notes on their Maturity Date;

     

    (c)           there
shall be a dissolution, termination of existence, suspension or discontinuance
of the Company’s business for a continuous period of 20 days or it ceases to
operate as going concern;

     

    
      
        
        

      

      
        B-7

        
          

        

      

      
        
        

      

       

    

    (d)           if
the Company shall:

     

    (i)           admit
in writing its inability to pay its debts generally as they become
due;

    (ii)          file
a petition in bankruptcy or a petition to take advantage of any insolvency
act;

    (iii)         convey
any material portion of the assets of the Company to a trustee, mortgage or
liquidating agent or make an assignment for the benefit of
creditors;

    

    (iv)         consent
to the appointment of a receiver, trustee, custodian or similar official, for
the Company or any material portion of the property or assets of the Company;
or

    

    (v)          on
a petition in bankruptcy filed against it, be adjudicated a bankrupt;
or

    

    (vi)         file
a petition or answer seeking reorganization or arrangement under the federal
bankruptcy laws or any other applicable law or statute of the United States of
America or any State, district or territory thereof;

    

    (e)           if
a court of competent jurisdiction shall enter an order, judgment, or decree
appointing, without the consent of the Company, a receiver of the whole or any
substantial part of the Company’s assets, and such order, judgment or decree
shall not be vacated or set aside or stayed within 60 days from the date of
entry thereof;

     

    (f)           if,
under the provisions of any other law for the relief or aid of debtors, any
court of competent jurisdiction shall assume custody or control of the whole or
any substantial part of the Company’s assets and such custody or control shall
not be terminated or stayed within 60 days from the date of assumption of such
custody or control;

     

    (g)          the
Company shall default in any of its obligations under any other promissory note,
indenture or any mortgage, credit agreement or other facility, indenture
agreement, factoring agreement or other instrument under which there may be
issued, or by which there may be secured or evidenced any indebtedness for
borrowed money or money due under any long term leasing or factoring arrangement
of the Company in an amount exceeding $100,000, whether such indebtedness now
exists or shall hereafter be created and such default shall result in such
indebtedness becoming or being declared due and payable prior to the date on
which it would otherwise become due and payable; or

     

    (h)          any
representation or warranty made by the Company in the Security Agreement was,
when made, untrue or misleading, the result of which is reasonably likely to
have a Material Adverse Effect.

     

    
      
        
        

      

      
        B-8

        
          

        

      

      
        
        

      

       

    

    9.           Guarantor.  Vyteris,
Inc., a Delaware corporation (the “Guarantor”), hereby
irrevocably, absolutely and unconditionally guarantees to the Purchaser the
prompt, complete and full performance, when due, and no matter how the same
shall become due, of all obligations and undertakings of the Company to
Purchaser under, by reason of, or pursuant to this Note and the Security
Agreement (the “Obligations”), including any amendments, extensions, renewals
and increases hereof or hereto, and all reasonable costs and expenses of the
Purchaser  incurred in the enforcement or collection of the foregoing,
including reasonable attorneys' fees and disbursements, court costs, collection
agency costs, and other ordinary out of pocket expenses incurred in enforcing
Purchaser’s rights hereunder or thereunder.  If the Company fails for
any reason whatsoever punctually to perform the Obligations, the Guarantor shall
cause each and every such Obligation to be satisfied and performed as if the
Guarantor instead of the Company were the primary obligor of the Company’s
obligations under this Note.  Guarantor hereby agrees that his
obligations under this Guarantee shall be unconditional and irrevocable and that
Guarantor shall be fully liable in respect of the Obligations and whether or not
any action has been taken to enforce the same or any judgment obtained against
the Company, whether or not any time or indulgence has been granted to the
Company by or on behalf of the Purchaser.  The Guarantor represents
and warrants to Purchaser that this guarantee is a valid and binding obligation
of the Guarantor and is enforceable against it in accordance with its
terms.

    

    10.           Remedies.  Subject
to the terms of the Security Agreement and the Requisite Consent, in case any
one or more of the Events of Default specified in Section 8 hereof
shall have occurred and be continuing, the Collateral Agent, on behalf of the
Purchaser and the other purchasers of the Notes, may proceed to protect and
enforce the Purchaser’s rights either by suit in equity and/or by action at law,
whether for the specific performance of any covenant or agreement contained in
this Note or in aid of the exercise of any power granted in this Note, or the
Collateral Agent may proceed to enforce the payment of all sums due upon this
Note or to enforce any other legal or equitable right of the
Purchaser.

     

    11.           Amendments and
Waivers.  The terms of this Note may be amended and the
observance of any term of this Note may be waived (either generally or in a
particular instance and either retroactively or prospectively) with the written
consent of the Company and the Requisite Consent, except with respect to the
Maturity Date and the Conversion Price, which can only be amended with the
Purchaser’s consent.

     

    12.         
Notices.  Any
notice, request or other document required or permitted to be given or delivered
to the Purchaser by the Company shall be delivered in accordance with the notice
provisions of the Subscription Agreement.

     

    With a copy to the Collateral
Agent:

     

    Collateral
Agents, LLC,

    111 West
57th Street, Suite 1416

    New York,
NY 10019

    Fax:
(212) 245-9102

    

    (ii)           Any
party may give any notice, request, consent or other communication under this
Note using any other means (including personal delivery, messenger service,
telecopy, first class mail or electronic mail), but no such notice, request,
consent or other communication shall be deemed to have been duly given unless
and until it is actually received by the party for whom it is
intended.  Any party may change the address to which notices,
requests, consents or other communications hereunder are to be delivered by
giving the other parties notice in the manner set forth in this Section
11.

    

    
      
        
        

      

      
        B-9

        
          

        

      

      
        
        

      

       

    

    13.           Severability.  The
unenforceability or invalidity of any provision or provisions of this Note as to
any persons or circumstances shall not render that provision or those provisions
unenforceable or invalid as to any other provisions or circumstances, and all
provisions hereof, in all other respects, shall remain valid and
enforceable.

     

    14.           Governing
Law.  This Note shall be governed by and construed under the
laws of the State of New York applicable to agreements made and to be performed
entirely within such jurisdiction.

     

    15.           Waivers.  The
nonexercise by either party of any of its rights hereunder in any particular
instance shall not constitute a waiver thereof in that or any subsequent
instance.

     

    [Signature
Page Follows]

     

    
      
        
        

      

      
        B-10

        
          

        

      

      
        
        

      

    

     

    IN
WITNESS WHEREOF, the Company and the Guarantor have caused its duly authorized
officers to execute this Note as of the date first written above.

     

    
      
        
          
            	
                    COMPANY:

                  
	 
      
	
                    VYTERIS, INC., a Nevada
      corporation

                  
	 
      
	
                    By:

                  	 
      
	 
      	
                    Name:

                  
	 
      	
                    Title

                  
	 
      
	
                    GUARANTOR:

                  
	 
      
	
                    VYTERIS, INC., a
      Delaware corporation

                  
	 
      
	
                    By:

                  	 
      
	 
      	
                    Name:

                  
	 
      	
                    Title

                  

          

        

      

    

    

    
      
        
        

      

      
        B-11NEITHER
THIS SECURITY NOR THE SECURITIES INTO WHICH THIS SECURITY IS EXERCISABLE HAVE
BEEN REGISTERED WITH THE SECURITIES AND EXCHANGE COMMISSION OR THE SECURITIES
COMMISSION OF ANY STATE IN RELIANCE UPON AN EXEMPTION FROM REGISTRATION UNDER
THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND, ACCORDINGLY,
MAY NOT BE OFFERED OR SOLD EXCEPT PURSUANT TO AN EFFECTIVE REGISTRATION
STATEMENT UNDER THE SECURITIES ACT OR PURSUANT TO AN AVAILABLE EXEMPTION FROM,
OR IN A TRANSACTION NOT SUBJECT TO, THE REGISTRATION REQUIREMENTS OF THE
SECURITIES ACT AND IN ACCORDANCE WITH APPLICABLE STATE SECURITIES LAWS AS
EVIDENCED BY A LEGAL OPINION OF COUNSEL TO THE TRANSFEROR TO SUCH EFFECT, THE
SUBSTANCE OF WHICH SHALL BE REASONABLY ACCEPTABLE TO THE COMPANY.

    

    FORM
OF

    

    COMMON
STOCK PURCHASE WARRANT

    

    
      	
              No.
      VYT-

            	
              Dated:
      ___________

            

    

    

    VYTERIS,
INC.

     

    THIS COMMON STOCK PURCHASE
WARRANT (the “Warrant”)
certifies that, for value received, [_____________] (the “Holder”),
is entitled, upon the terms and subject to the limitations on exercise and the
conditions hereinafter set forth, at any time on or after the date hereof (the
“Initial
Exercise Date”) and on or prior to the close of business on the fifth
(5th) year anniversary of the Initial Exercise Date (the “Termination
Date”), to subscribe for and purchase from Vyteris, Inc., a Nevada
corporation (the “Company”),
up to [________]1
shares (the “Warrant
Shares”) of Common Stock, par value $0.015 per share, of the Company (the
“Common
Stock”).  The purchase price of one share of Common Stock under
this Warrant shall be equal to the Exercise Price, as defined in Section
2(b).

     

    1.           Definitions.  Capitalized
terms used and not otherwise defined herein shall have the meanings set forth in
that certain Subscription Agreement (the “Subscription
Agreement”) between the Company and the Holder which is attached to that
certain Confidential Private Placement Memorandum, dated November 4, 2009, as
same may be amended or supplemented from time to time (collectively referred to
herein as the “Memorandum”).

    _____________________

    
      1  Such
number shall be inserted at closing and shall be 100% of the shares of Common
Stock that the Note is initially convertible into.

      
         

      

    

    
      
         

      

      
         

        
          

        

      

      
         

      

       

    

    2.           Exercise.

     

    (a)           Exercise of
Warrant.  Exercise of the purchase rights represented by this
Warrant may be made, in whole or in part, at any time or times on or after the
Initial Exercise Date and on or before the Termination Date by delivery to the
Company of a duly executed facsimile copy of the Notice of Exercise Form annexed
hereto (or such other office or agency of the Company as it may designate by
notice in writing to the registered Holder at the address of such Holder
appearing on the books of the Company); provided, however, within
five (5) trading days of the date said Notice of Exercise is delivered to the
Company, the Holder shall have surrendered this Warrant to the Company and the
Company shall have received  payment of the aggregate Exercise Price
of the shares thereby purchased by wire transfer or check drawn on a United
States bank.

     

    (b)           Exercise
Price.  The exercise price of the Common Stock under this
Warrant shall be $[____]2,
subject to adjustment hereunder (the “Exercise
Price”).

     

    (c)           Cashless
Exercise.  This Warrant may also be exercised at any time or
times on or after the Initial Exercise Date and on or before the Termination
Date by means of a “cashless exercise” in which the Holder shall be entitled to
receive a certificate for the number of Warrant Shares equal to the quotient
obtained by dividing [(A-B) (X)] by (A), where:

     

    
      
        	
              	
                (A)
      =

              	
                the
      VWAP (as defined below) on the trading day immediately preceding the date
      of such election;

              

      

    

    

    
      
        	
              	
                (B)
      =

              	
                the
      Exercise Price of this Warrant, as adjusted;
and

              

      

    

    

    
      
        	
              	
                (X)
      =

              	
                the
      number of Warrant Shares issuable upon exercise of this Warrant in
      accordance with the terms of this Warrant by means of a cash exercise
      rather than a cashless
exercise.

              

      

    

    

              “Trading
Market” means whichever of the New York Stock Exchange, the NYSE AMEX,
the Nasdaq Global Select Market, the Nasdaq Global Market, the Nasdaq Capital
Market on which the Common Stock is listed or quoted for trading on the date in
question.

    

              “VWAP”
means, for any date, the price determined by the first of the following clauses
that applies: (a) if the Common Stock is then listed or quoted on a Trading
Market, the daily volume weighted average price of the Common Stock for such
date (or the nearest preceding date) on the Trading Market on which the Common
Stock is then listed or quoted as reported by Bloomberg Financial L.P. (based on
a trading day from 9:30 a.m. Eastern Time to 4:02 p.m. Eastern Time);
(b)  if the Common Stock is not then listed or quoted on a Trading
Market and if prices for the Common Stock are then quoted on the OTC Bulletin
Board, the volume weighted average price of the Common Stock for such date (or
the nearest preceding date) on the OTC Bulletin Board; (c) if the Common Stock
is not then listed or quoted on the OTC Bulletin Board and if prices for the
Common Stock are then reported in the “Pink Sheets” published by the Pink
Sheets, LLC (or a similar organization or agency succeeding to its functions of
reporting prices), the most recent bid price per share of the Common Stock so
reported; or (c) in all other cases, the fair market value of a share of Common
Stock as determined by an independent appraiser selected in good faith by the
Company.

    _____________________

    
      2 
Such price to be inserted at closing and shall be equal to 125% of
the initial conversion price of the Notes (100% of the initial conversion price
of the Notes for purchasers that participate in the first closing of the
offering).

    

     

    
      
         

      

      
        C-2

        
          

        

      

      
         

      

    

     

    (d)           Mechanics of
Exercise.

     

    (i)           Authorization of Warrant
Shares.  The Company covenants that all Warrant Shares which
may be issued upon the exercise of the purchase rights represented by this
Warrant will, upon exercise of the purchase rights represented by this Warrant,
be duly authorized, validly issued, fully paid and nonassessable and free from
all taxes, liens and charges imposed by the Company in respect of the issue
thereof (other than taxes in respect of any transfer occurring contemporaneously
with such issue).

     

    (ii)           Delivery of Certificates
Upon Exercise.  Certificates for shares purchased hereunder
shall be transmitted by the transfer agent of the Company to the Holder by
crediting the account of the Holder’s prime broker with the Depository Trust
Company through its Deposit Withdrawal Agent Commission (“DWAC”)
system if the Company is a participant in such system, and otherwise by physical
delivery to the address specified by the Holder in the Notice of Exercise within
three (3) trading days from the delivery to the Company of the Notice of
Exercise Form, surrender of this Warrant and payment of the aggregate Exercise
Price as set forth above (“Warrant Share
Delivery Date”).  This Warrant shall be deemed to have been
exercised on the date the Exercise Price and completed Notice of Exercise are
received by the Company.  The Warrant Shares shall be deemed to have
been issued, and Holder or any other person so designated to be named therein
shall be deemed to have become a holder of record of such shares for all
purposes, as of the date the Warrant has been exercised by payment to the
Company of the Exercise Price and all taxes required to be paid by the Holder,
if any, pursuant to Section 2(d)(vi)
prior to the issuance of such shares, have been paid.

     

    (iii)           Delivery of New Warrants
Upon Exercise.  If this Warrant shall have been exercised in
part, the Company shall, at the time of delivery of the certificate or
certificates representing Warrant Shares, deliver to Holder a new Warrant
evidencing the rights of Holder to purchase the unpurchased Warrant Shares
called for by this Warrant, which new Warrant shall in all other respects be
identical with this Warrant.

     

    (iv)           Buy-In
Rights.  In addition to any other rights available to a Holder,
if the Company fails to deliver to the Holder a certificate representing Warrant
Shares by the fifth trading day after the date on which delivery of such
certificate is required by this Warrant, and if after such fifth trading day the
Holder purchases (in an open market transaction or otherwise) shares of Common
Stock to deliver in satisfaction of a sale by the Holder of the Warrant Shares
that the Holder anticipated receiving from the Company (a “Buy-In”), then the Company
shall, within ten trading days after the Holder’s request, honor its obligation
to deliver to the Holder a certificate or certificates representing such Common
Stock and pay cash to the Holder in an amount equal to the excess (if any) of
the amount equal to the Holder’s total purchase price (including brokerage
commissions, if any) for the shares of Common Stock so purchased over the
product of (A) such number of shares of Common Stock, times (B) the Closing
Price on the date of the event giving rise to the Company’s obligation to
deliver such certificate.

     

    
      
         

      

      
        C-3

        
          

        

      

      
         

      

       

    

    (v)           No Fractional Shares or
Scrip.  No fractional shares or scrip representing fractional
shares shall be issued upon the exercise of this Warrant.  As to any
fraction of a share which Holder would otherwise be entitled to purchase upon
such exercise, the Company shall pay a cash adjustment in respect of such final
fraction in an amount equal to such fraction multiplied by the Exercise
Price.

     

    (vi)           Charges, Taxes and
Expenses.  Issuance of certificates for Warrant Shares shall be
made without charge to the Holder for any issue or transfer tax or other
incidental expense in respect of the issuance of such certificate, all of which
taxes and expenses shall be paid by the Company, and such certificates shall be
issued in the name of the Holder or in such name or names as may be directed by
the Holder; provided,
however, that in the event certificates for Warrant Shares are to be
issued in a name other than the name of the Holder, this Warrant when
surrendered for exercise shall be accompanied by the Assignment Form attached
hereto duly executed by the Holder; and the Company may require, as a condition
thereto, the payment of a sum sufficient to reimburse it for any transfer tax
incidental thereto.

     

    (vii)           Closing of
Books.  The Company will not close its stockholder books or
records prior to the Termination Date in any manner which prevents the timely
exercise of this Warrant, pursuant to the terms hereof.

     

    3.           Certain
Adjustments.

     

    (a)           Stock Dividends and
Splits. If the Company, at any time while this Warrant is outstanding:
(A) pays a stock dividend or otherwise make a distribution or distributions on
shares of its Common Stock or any other equity or equity equivalent securities
payable in shares of Common Stock (which, for avoidance of doubt, shall not
include any shares of Common Stock issued by the Company pursuant to this
Warrant), (B) subdivides outstanding shares of Common Stock into a larger number
of shares, (C) combines (including by way of reverse stock split) outstanding
shares of Common Stock into a smaller number of shares, or (D) issues by
reclassification of shares of the Common Stock any shares of capital stock of
the Company, then in each case the Exercise Price shall be multiplied by a
fraction of which the numerator shall be the number of shares of Common Stock
(excluding treasury shares, if any) outstanding immediately before such event
and of which the denominator shall be the number of shares of Common Stock
outstanding immediately after such event and the number of shares issuable upon
exercise of this Warrant shall be proportionately adjusted.  Any
adjustment made pursuant to this Section 3(a) shall
become effective immediately after the record date for the determination of
stockholders entitled to receive such dividend or distribution and shall become
effective immediately after the effective date in the case of a subdivision,
combination or re-classification.

     

    
      
         

      

      
        C-4

        
          

        

      

      
         

      

       

    

    (b)           Additional Issuances of
Equity Securities.  If the Company, at any time while this
Warrant is outstanding, shall issue or sell any Equity Securities (as defined
below) at an effective price per share less than the then effective Exercise
Price (such lower price, the “Base Share
Price” and such issuances collectively, a “Dilutive
Issuance”), as adjusted hereunder (if the holder of the Equity Securities
so issued shall at any time, whether by operation of purchase price adjustments,
reset provisions, conversion, floating conversion, exercise or exchange prices
or otherwise, or due to warrants, options or rights per share which is issued in
connection with such issuance, be entitled to receive shares of Common Stock at
an effective price per share which is less than the Exercise Price, such
issuance shall be deemed to have occurred for less than the Exercise Price on
such date of the Dilutive Issuance), then, the Exercise Price shall be reduced
and only reduced to equal the Base Share Price.  Notwithstanding the
foregoing, no adjustments shall be made, paid or issued under this Section 3(b) in
respect of Exempt Issuances (as defined below).  The Company shall
notify the Holder in writing as promptly as reasonably possible following the
issuance of any Equity Securities subject to this section, indicating therein
the applicable issuance price, or of applicable reset price, exchange price,
conversion price and other pricing terms (such notice the “Dilutive Issuance
Notice”).  For purposes of clarification, whether or not the
Company provides a Dilutive Issuance Notice pursuant to this Section 3(b), upon
the occurrence of any Dilutive Issuance while this Warrant is outstanding, after
the date of such Dilutive Issuance the Holder is entitled to the Base Share
Price regardless of whether the Holder accurately refers to the Base Share Price
in the Notice of Exercise.

     

    For purposes of this Section 3(b), the
following definitions shall apply:

     

    “Common Stock
Equivalents” means any securities of the Company or its subsidiaries
which would entitle the holder thereof to acquire at any time Common Stock,
including, without limitation, any debt, preferred stock, rights, options,
warrants or other instrument that is at any time convertible into or exercisable
or exchangeable for, or otherwise entitles the holder thereof to receive, Common
Stock.

     

    “Equity
Securities” means (i) Common Stock and (ii) Common Stock
Equivalents.

    

    “Exempt
Issuance” means (i) any Equity Securities issued or issuable pursuant to
options, warrants or other rights issued or issuable to employees, officers or
directors of, or consultants or advisors to the Company or any subsidiary,
pursuant to equity incentive plans or other employee benefit arrangements; (ii)
any Equity Securities issued or issuable pursuant to any rights or agreements,
options, warrants or convertible securities outstanding as of the Closing Date;
(iii) any Equity Securities issued or issuable for consideration other than cash
pursuant to a merger, consolidation, strategic alliance, acquisition or similar
business combination; (iv) any Equity Securities issued or issuable in
connection with any stock split, stock dividend or recapitalization by the
Company; (v) any Equity Securities issued or issuable pursuant to any equipment
loan or leasing arrangement, real property leasing arrangement, or debt
financing from a bank or similar financial or lending institution; and (vi) any
Equity Securities issued or issuable to the Placement Agent or its
affiliates.  For clarification purposes, warrants that are issued at a
Base Share Price pursuant to the Memorandum at closings subsequent to the
issuance of this Warrant shall not be deemed to be
an Exempt Issuance hereunder.

    

    (c)           Warrant
Shares.   Simultaneously with any adjustment to the
Exercise Price pursuant to paragraph (b) of this Section, the number of Warrant
Shares that may be purchased upon exercise of this Warrant shall be increased or
decreased proportionately, as applicable, so that after such adjustment the
aggregate Exercise Price payable hereunder for the increased or decreased, as
applicable, number of Warrant Shares shall be the same as the aggregate Exercise
Price in effect immediately prior to such adjustment.

    

    
      
         

      

      
        C-5

        
          

        

      

      
         

      

       

    

    (d)           Fundamental
Transaction. If, at any time while this Warrant is outstanding, (A) the
Company effects any merger or consolidation of the Company with or into another
Person (other than a transaction effected solely to change the domicile of the
Company), (B) the Company effects any sale of all or substantially all of its
assets in one or a series of related transactions, (C) any tender offer or
exchange offer (whether by the Company or another Person) is completed pursuant
to which holders of Common Stock are permitted to tender or exchange their
shares for other securities, cash or property, (D) consummate a stock purchase
agreement or other business combination (including, without limitation, a
reorganization, recapitalization, spin-off or scheme of arrangement) with
another Person whereby such other Person acquires more than the 50% of the
outstanding shares of Common Stock (not including any shares of Common Stock
held by the other Person or other Persons making or party to, or associated or
affiliated with the other Persons making or party to, such stock purchase
agreement or other business combination) or (E) the Company effects any
reclassification of the Common Stock or any compulsory share exchange pursuant
to which the Common Stock is effectively converted into or exchanged for other
securities, cash or property (in any such case, a “Fundamental
Transaction”), then, upon any subsequent exercise of this Warrant, the
Holder shall have the right to receive, for each Warrant Share that would have
been issuable upon such exercise immediately prior to the occurrence of such
Fundamental Transaction upon exercise of this Warrant, the number of shares of
Common Stock of the successor or acquiring corporation or of the Company, if it
is the surviving corporation, and any additional consideration (the “Alternate
Consideration”) receivable upon or as a result of such Fundamental
Transaction by a Holder, of the number of shares of Common Stock for which this
Warrant is exercisable immediately prior to such event.  For purposes
of any such exercise, the determination of the Exercise Price shall be
appropriately adjusted to apply to such Alternate Consideration based on the
amount of Alternate Consideration issuable in respect of one share of Common
Stock in such Fundamental Transaction, and the Company shall apportion the
Exercise Price among the Alternate Consideration in a reasonable manner
reflecting the relative value of any different components of the Alternate
Consideration.  If holders of Common Stock are given any choice as to
the securities, cash or property to be received in a Fundamental Transaction,
then the Holder shall be given the same choice as to the Alternate Consideration
it receives upon any exercise of this Warrant following such Fundamental
Transaction.  To the extent necessary to effectuate the foregoing
provisions, any successor to the Company or surviving entity in such Fundamental
Transaction shall issue to the Holder a new warrant consistent with the
foregoing provisions and evidencing the Holder’s right to exercise such warrant
into Alternate Consideration. The terms of any agreement pursuant to which a
Fundamental Transaction is effected shall include terms requiring any such
successor or surviving entity to comply with the provisions of this Section 3(d) and
insuring that this Warrant (or any such replacement security) will be similarly
adjusted upon any subsequent transaction analogous to a Fundamental
Transaction.

     

    (e)           Calculations. All
calculations under this Section 3 shall be
made to the nearest cent or the nearest 1/100th of a share, as the case may be.
For purposes of this Section 3, the number
of shares of Common Stock deemed to be issued and outstanding as of a given date
shall be the sum of the number of shares of Common Stock (excluding treasury
shares, if any) issued and outstanding.

     

    
      
         

      

      
        C-6

        
          

        

      

      
         

      

       

    

    (f)           Voluntary Adjustment By
Company. The Company may at any time during the term of this Warrant
reduce the then current Exercise Price to any amount and for any period of time
deemed appropriate by the board of directors of the Company.

     

    (h)           Notice to
Holders.

     

    (i)           Adjustment to Exercise
Price. Whenever the Exercise Price is adjusted pursuant to this Section 3, the
Company shall promptly as reasonably possible mail to each Holder a notice
setting forth the Exercise Price after such adjustment.  If the
Company issues a variable rate security, the Company shall be deemed to have
issued Equity Securities at the lowest possible conversion or exercise price at
which such securities may be converted or exercised in the case of a Variable
Rate Transaction (as defined in the following sentence).  The term
“Variable
Rate Transaction” shall mean a transaction in which the Company issues or
sells (i) any debt or equity securities that are convertible into, exchangeable
or exercisable for, or include the right to receive additional shares of Common
Stock either (A) at a conversion, exercise or exchange rate or other price that
is based upon and/or varies with the trading prices of or quotations for the
shares of Common Stock at any time after the initial issuance of such debt or
equity securities, or (B) with a conversion, exercise or exchange price that is
subject to being reset at some future date after the initial issuance of such
debt or equity security or upon the occurrence of specified or contingent events
directly or indirectly related to the business of the Company or the market for
the Common Stock or (ii) enters into any agreement, including, but not limited
to, an equity line of credit, whereby the Company may sell securities at a
future determined price.

     

    (ii)           Notice to Allow Exercise by
Holder. If (A) the Company shall declare a dividend (or any other
distribution) on the Common Stock; (B) the Company shall declare a special
nonrecurring cash dividend on or a redemption of the Common Stock; (C) the
Company shall authorize the granting to all holders of the Common Stock rights
or warrants to subscribe for or purchase any shares of capital stock of any
class or of any rights; (D) the approval of any stockholders of the Company
shall be required in connection with any reclassification of the Common Stock,
any consolidation or merger to which the Company is a party, any sale or
transfer of all or substantially all of the assets of the Company, of any
compulsory share exchange whereby the Common Stock is converted into other
securities, cash or property; (E) the Company shall authorize the voluntary or
involuntary dissolution, liquidation or winding up of the affairs of the
Company; then, in each case, the Company shall cause to be mailed to the Holder
at its last address as it shall appear upon the Warrant Register of the Company,
at least five (5) calendar days prior to the applicable record or effective date
hereinafter specified, a notice stating (x) the date on which a record is to be
taken for the purpose of such dividend, distribution, redemption, rights or
warrants, or if a record is not to be taken, the date as of which the holders of
the Common Stock of record to be entitled to such dividend, distributions,
redemption, rights or warrants are to be determined or (y) the date on which
such reclassification, consolidation, merger, sale, transfer or share exchange
is expected to become effective or close, and the date as of which it is
expected that holders of the Common Stock of record shall be entitled to
exchange their shares of the Common Stock for securities, cash or other property
deliverable upon such reclassification, consolidation, merger, sale, transfer or
share exchange; provided,
that the failure to mail such notice or any defect therein or in the
mailing thereof shall not affect the validity of the corporate action required
to be specified in such notice.  The Holder is entitled to exercise
this Warrant during the 5-day period commencing on the date of such notice to
the effective date of the event triggering such notice.

     

    
      
         

      

      
        C-7

        
          

        

      

      
         

      

       

    

    4
..           Transfer of
Warrant.

     

    (a)           Transferability.  Subject
to compliance with any applicable securities laws and the conditions set forth
in Sections
5(a) and 4(d) hereof and to
the provisions of the Subscription Agreement, this Warrant and all rights
hereunder are transferable, in whole or in part, upon surrender of this Warrant
at the principal office of the Company, together with a written assignment of
this Warrant substantially in the form attached hereto duly executed by the
Holder or its agent or attorney and funds sufficient to pay any transfer taxes
payable upon the making of such transfer.  Upon such surrender and, if
required, such payment, the Company shall execute and deliver a new Warrant or
Warrants in the name of the assignee or assignees and in the denomination or
denominations specified in such instrument of assignment, and shall issue to the
assignor a new Warrant evidencing the portion of this Warrant not so assigned,
and this Warrant shall promptly be cancelled.  A Warrant, if properly
assigned, may be exercised by a new holder for the purchase of Warrant Shares
without having a new Warrant issued.

     

    (b)           New Warrants. This
Warrant may be divided or combined with other Warrants upon presentation hereof
at the aforesaid office of the Company, together with a written notice
specifying the names and denominations in which new Warrants are to be issued,
signed by the Holder or its agent or attorney.  Subject to compliance
with Section
4(a), as to any transfer which may be involved in such division or
combination, the Company shall execute and deliver a new Warrant or Warrants in
exchange for the Warrant or Warrants to be divided or combined in accordance
with such notice.

     

    (c)           Warrant Register. The
Company shall register this Warrant, upon records to be maintained by the
Company for that purpose (the “Warrant
Register”), in the name of the record Holder hereof from time to
time.  The Company may deem and treat the registered Holder of this
Warrant as the absolute owner hereof for the purpose of any exercise hereof or
any distribution to the Holder, and for all other purposes, absent actual notice
to the contrary.

     

    (d)           Transfer
Restrictions. If, at the time of the surrender of this Warrant in connection with
any transfer of this Warrant, the transfer of this Warrant shall not be
registered pursuant to an effective registration statement under the Securities Act and under applicable state securities or blue sky laws, the
Company may require, as a condition of allowing such transfer (i) that the
Holder or transferee of this Warrant, as the case may be, furnish to the Company
a written opinion of counsel (which opinion shall be in form, substance and
scope customary for opinions of counsel in comparable transactions) to the
effect that such transfer may be made without registration under the Securities Act of 1933 (the “Securities
Act”) and under applicable state securities
or blue sky laws, (ii) that the holder or transferee execute and deliver to the
Company an investment letter in form and substance acceptable to the Company and
(iii) that the transferee be an “accredited
investor” as defined in Rule 501(a)(1), (a)(2), (a)(3), (a)(7),
or (a)(8) promulgated under the Securities Act or a qualified institutional
buyer as defined in Rule 144A(a) under the Securities Act.

     

    
      
         

      

      
        C-8

        
          

        

      

      
         

      

       

    

    5. 
           Miscellaneous.

     

    (a)           Title to
Warrant.  Prior to the Termination Date and subject to
compliance with applicable laws and Section 4 of this
Warrant, this Warrant and all rights hereunder are transferable, in whole or in
part, at the office or agency of the Company by the Holder in person or by duly
authorized attorney, upon surrender of this Warrant together with the Assignment
Form annexed hereto properly endorsed.  The transferee shall sign an
investment letter in form and substance reasonably satisfactory to the
Company.

     

    (b)           No Rights as Shareholder
Until Exercise.  Except as may be specifically set forth
herein, this Warrant does not entitle the Holder to any voting rights or other
rights as a shareholder of the Company prior to the exercise
hereof.  Upon the surrender of this Warrant and the payment of the
aggregate Exercise Price (or by means of a cashless exercise), the Warrant
Shares so purchased shall be and be deemed to be issued to such Holder as the
record owner of such shares as of the close of business on the later of the date
of such surrender or payment.

     

    (c)           Loss, Theft, Destruction or
Mutilation of Warrant. The Company covenants that upon receipt by the
Company of evidence reasonably satisfactory to it of the loss, theft,
destruction or mutilation of this Warrant or any stock certificate relating to
the Warrant Shares, and in case of loss, theft or destruction, of indemnity or
security reasonably satisfactory to it (which, in the case of the Warrant, shall
not include the posting of any bond), and upon surrender and cancellation of
such Warrant or stock certificate, if mutilated, the Company will make and
deliver a new Warrant or stock certificate of like tenor and dated as of such
cancellation, in lieu of such Warrant or stock certificate.

     

    (d)           Saturdays, Sundays,
Holidays, etc.  If the last or appointed day for the taking of
any action or the expiration of any right required or granted herein shall be a
Saturday, Sunday or a legal holiday, then such action may be taken or such right
may be exercised on the next succeeding day not a Saturday, Sunday or legal
holiday.

     

    (e)           Authorized
Shares.  The Company covenants that during the period the
Warrant is outstanding, it will reserve from its authorized and unissued Common
Stock a sufficient number of shares to provide for the issuance of the Warrant
Shares upon the exercise of any purchase rights under this
Warrant.  The Company further covenants that its issuance of this
Warrant shall constitute full authority to its officers who are charged with the
duty of executing stock certificates to execute and issue the necessary
certificates for the Warrant Shares upon the exercise of the purchase rights
under this Warrant.  The Company will take all such reasonable action
as may be necessary to assure that such Warrant Shares may be issued as provided
herein without violation of any applicable law or regulation, or of any
requirements of the Trading Market or OTC Bulletin Board upon which the Common
Stock may be listed/traded.

     

    
      
         

      

      
        C-9

        
          

        

      

      
         

      

       

    

    Except
and to the extent as waived or consented to by the Holder, the Company shall not
by any action, including, without limitation, amending its certificate of
incorporation or through any reorganization, transfer of assets, consolidation,
merger, dissolution, issue or sale of securities or any other voluntary action,
avoid or seek to avoid the observance or performance of any of the terms of this
Warrant, but will at all times in good faith assist in the carrying out of all
such terms and in the taking of all such actions as may be necessary or
appropriate to protect the rights of Holder as set forth in this Warrant against
impairment.  Without limiting the generality of the foregoing, the
Company will (a) not increase the par value of any Warrant Shares above the
amount payable therefor upon such exercise immediately prior to such increase in
par value, (b) take all such action as may be necessary or appropriate in order
that the Company may validly and legally issue fully paid and nonassessable
Warrant Shares upon the exercise of this Warrant, and (c) use commercially
reasonable efforts to obtain all such authorizations, exemptions or consents
from any public regulatory body having jurisdiction thereof as may be necessary
to enable the Company to perform its obligations under this
Warrant.

     

    Before
taking any action which would result in an adjustment in the number of Warrant
Shares for which this Warrant is exercisable or in the Exercise Price, the
Company shall obtain all such authorizations or exemptions thereof, or consents
thereto, as may be necessary from any public regulatory body or bodies having
jurisdiction thereof.

     

    (f)           Jurisdiction. All
questions concerning the construction, validity, enforcement and interpretation
of this Warrant shall be determined in accordance with the provisions of the
Subscription Agreement.

     

    (g)           Restrictions.  The
Holder acknowledges that the Warrant Shares acquired upon the exercise of this
Warrant, if not registered, will have restrictions upon resale imposed by state
and federal securities laws.

     

    (h)           Nonwaiver.  No
course of dealing or any delay or failure to exercise any right hereunder on the
part of Holder shall operate as a waiver of such right or otherwise prejudice
Holder’s rights, powers or remedies, notwithstanding the fact that all rights
hereunder terminate on the Termination Date.

     

    (i)           Notices.  Any
notice, request or other document required or permitted to be given or delivered
to the Holder by the Company shall be delivered in accordance with the notice
provisions of the Subscription Agreement.

     

    (j)           Limitation of
Liability.  No provision hereof, in the absence of any
affirmative action by Holder to exercise this Warrant or purchase Warrant
Shares, and no enumeration herein of the rights or privileges of Holder, shall
give rise to any liability of Holder for the purchase price of any Common Stock
or as a stockholder of the Company, whether such liability is asserted by the
Company or by creditors of the Company.

     

    (k)           Successors and
Assigns.  Subject to applicable securities laws, this Warrant
and the rights and obligations evidenced hereby shall inure to the benefit of
and be binding upon the successors of the Company and the successors and
permitted assigns of Holder.  The provisions of this Warrant are
intended to be for the benefit of all Holders from time to time of this Warrant
and shall be enforceable by any such Holder or holder of Warrant
Shares.

     

    (l)           Amendment.  This
Warrant may be modified or amended or the provisions hereof waived with the
written consent of the Company and the Holder.

     

    
      
         

      

      
        C-10

        
          

        

      

      
         

      

       

    

    (m)           Severability.  Wherever
possible, each provision of this Warrant shall be interpreted in such manner as
to be effective and valid under applicable law, but if any provision of this
Warrant shall be prohibited by or invalid under applicable law, such provision
shall be ineffective to the extent of such prohibition or invalidity, without
invalidating the remainder of such provisions or the remaining provisions of
this Warrant.

     

    (n)           Headings.  The
headings used in this Warrant are for the convenience of reference only and
shall not, for any purpose, be deemed a part of this Warrant.

     

    [Remainder
of page left intentionally blank]

     

    
      
         

      

      
        C-11

        
          

        

      

      
         

      

    

     

    IN
WITNESS WHEREOF, the Company has caused this Warrant to be executed by its
officer thereunto duly authorized as of the date first set forth
above.

     

    
      
        
          
            
              	
                      VYTERIS,
      INC.

                    
	 
      
	
                      By:

                    	 
      
	 
      
	
                      Print
      Name:

                    	 
      
	 
      
	
                      Title:

                    	 
      

            

          

        

      

    

    

    
      
         

      

      
        
        

        
          

        

      

      
         

      

    

     

    NOTICE
OF EXERCISE

    

    TO:           VYTERIS,
INC.

    

    (1)   The
undersigned hereby elects to purchase ________ Warrant Shares of the Company
pursuant to the terms of the attached Warrant (only if exercised in full), and
tenders herewith payment of the exercise price in full, together with all
applicable transfer taxes, if any.

     

    (2)   Payment
shall take the form of (check applicable box):

     

    [  ]
in lawful money of the United States; or

     

    [ ] the
cancellation of such number of Warrant Shares as is necessary, in accordance
with the formula set forth in subsection 2(c), to exercise this Warrant with
respect to the maximum number of Warrant Shares purchasable pursuant to the
cashless exercise procedure set forth in subsection 2(c).

     

    (3)   Please
issue a certificate or certificates representing said Warrant Shares in the name
of the undersigned or in such other name as is specified below:

     

    _______________________________

     

    The
Warrant Shares shall be delivered to the following:

    

    _______________________________

    

    _______________________________

    

    _______________________________

    

    (4)  Accredited
Investor.  The undersigned is an “accredited investor” as
defined in Regulation D promulgated under the Securities Act of 1933, as
amended.

     

    [SIGNATURE
OF HOLDER]

     

    Name of
Investing Entity:
________________________________________________________

     

    Signature of Authorized Signatory of
Investing Entity: ___________________________________

     

    Name of
Authorized Signatory:
____________________________________________________

     

    Title of
Authorized Signatory:
_____________________________________________________

     

    Date:
_________________________________________________________________________

     

    
      
         

      

      
        
        

        
          

        

      

      
         

      

    

     

    ASSIGNMENT
FORM

    

    (To
assign the foregoing warrant, execute

    this form
and supply required information.

    Do not
use this form to exercise the warrant.)

     

    FOR VALUE
RECEIVED, the foregoing Warrant and all rights evidenced thereby are hereby
assigned to

     

    _______________________________________________
whose address is

    

    _______________________________________________________________.

    

    _______________________________________________________________

    

    
      	 
      	
              Dated:  ______________,
      _______

            

    

     

    
      	 
      	
              Holder’s
      Signature:

            	
              _____________________________

            
	 
      	 
      	 
      
	 
      	
              Holder’s
      Address:

            	
              _____________________________

            
	 
      	 
      	 
      
	 
      	 
      	
              _____________________________

            

    

    

    Signature
Guaranteed:  ___________________________________________

     

    NOTE:  The
signature to this Assignment Form must correspond with the name as it appears on
the face of the Warrant, without alteration or enlargement or any change
whatsoever, and must be guaranteed by a bank or trust
company.  Officers of corporations and those acting in a fiduciary or
other representative capacity should file proper evidence of authority to assign
the foregoing Warrant.

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