Document:

EX-10.35

 Exhibit 10.35 

LICENSE AGREEMENT 
  

			
	A	 	LICENSOR – NAME, NOTICE AND RENT PAYMENT ADDRESS
	  
 Licensor:
        JAMESTOWN 21-23-25 DRYDOCK, L.P.

Address:          c/o Jamestown

Ponce City Market, 7Th Floor
 675 Ponce de Leon Avenue, NE

Atlanta, Georgia 30308

Attn: General Counsel; Asset Manager: Bronstein

		 
	B	 	LICENSEE – NAME AND NOTICE ADDRESS
	  
 Licensee:
       GINKGO BIOWORKS, INC.
 Address:          27 Drydock Avenue,
Floor 8
 Boston, Massachusetts 02210

		
	C	 	TERMS

  

			
	Effective Date:	 	September 11, 2020
		
	Premises:	 	Suite 23-110W containing 1,694 square feet as shown on Exhibit A, located in the building commonly known as the Bronstein Building (the “Building”).
		
	Percentage Rent:	 	Four percent (4%) of Gross Sales (as defined below)
		
	Utilities:	 	No charge for use of electricity, water and HVAC. Licensor has right to impose a surcharge as set forth in Section 3(C).
		
	Term:	 	 Commencement Date: September 14, 2020

  

From and after the Commencement Date, Licensee shall have the right to occupy the Premises on a
month-to-month basis. Licensor and Licensee shall each have the right to terminate this Agreement upon a minimum of sixty (60) days prior written notice to the
other party.

		
	Permitted Use:	 	Subject to all applicable law, and further provided Licensee obtains all requisite permits, Licensee shall have the right to operate a COVID-19 testing site from the Premises and uses
accessory thereto. Any and all testing and related services shall be performed by licensed medical professions when required in accordance with all applicable law.

  

			
	Executed as of the Effective Date:
		
	For and on behalf of the Licensor:	 	For and on behalf of the Licensee:
		
	JAMESTOWN 21-23-25 DRYDOCK, L.P.,	 	GINKGO BIOWORKS, INC.,
	a Delaware limited partnership	 	a Delaware corporation

  

									
	By:	 	JT 21-23-25 Drydock Crop.,	 	By:	 	 /s/ Barry Canton

		 	a Delaware corporation	 	Name:	 	Barry Canton
		 	its general partner	 	Title:	 	Co-Founder, CTO
		 		 		 		 	
		 	By:	 	 /s/ Dana Griffin
	 		 	
		 		 	Name:  Dana Griffin	 		 	
		 		 	Authorized Signatory	 		 	

 1.     Agreement. We (“Licensor”) hereby license to you
(“Licensee”) the Premises described on Exhibit A, at the Building for the Term set forth on page one of this License Agreement (“Agreement”). No provision of this Agreement will be deemed to have been waived
by us unless the waiver is in writing signed by us. This Agreement may not be modified or discharged, except in writing.  
 2.
    Use. (A) You must use the Premises only for the use stated on page one. During the Term, you will have the right to enter the Premises at any time. Any personal property left outside the Premises will be
discarded, at your expense. We will not be liable for any damage to or loss of objects left in these areas. You must keep the Premises clean, at your expense, in a manner reasonably satisfactory to us. Licensee may not use the Premises in violation
of any existing exclusive use agreement between Licensor and any other tenant or licensee of the Building. Licensee shall have no right to sell or serve alcoholic beverages on the Premises. 

(B)     At all times, your use of electrical current may not exceed the capacity of existing installations. You may not
alter any wiring installations or other electrical facilities without our prior written consent. We are not responsible for any changes in the quantity and/or quality of electrical service. 

(C)     You shall keep the Premises, the Building and your interest therein free and clear of any lien or encumbrance of
any kind including, without limitation, mechanics’ liens. 
 3.     Payment. (A) Commencing on the
Commencement Date, you agree to pay all additional rents and charges, as set forth on page one, as set forth herein. You agree to pay all other additional rents and charges within 10 business days from delivery of written demand, in each case at the
address on page one, or any other address we designate, without any setoff, defense or deduction. 
 (B)     If you
fail to pay any Percentage Rent or additional rent (collectively “Rent”) on the due date thereof, and such failure continues for more than ten (10) days after written notice, then in addition to our other rights under this
Agreement, you shall be in default and this Agreement shall be terminated at our election while such default continues. However, if we give you such 10-day notice more than one time in any 12-month period, then we will have no obligation to give written notice of any subsequent default and we will thereafter have the right to terminate this Agreement if you fail to pay any rent or additional rent on
the due date. If we elect to terminate this Agreement, we shall terminate the Agreement by giving you a cancellation notice. Such cancellation notice will state the date on which the Term will end, which may be no less than ten (10) days after
the date of the notice. On the cancellation date set forth in such notice, this Agreement and the Term hereof shall cease, come to an end and expire as fully and completely and with the same force and effect as if the cancellation date fixed in said
cancellation notice was the date originally fixed herein as the expiration date. 
 (C)     If the value of the water,
electrical service or HVAC furnished to Licensee exceeds a reasonable amount (as determined in Licensor’s sole but reasonable discretion), Licensor may impose a surcharge to reflect the value of such utilities provided, which will be paid as
additional rent. We will provide reasonable documentation of the basis for the increase.

 (D)     You agree to pay Percentage Rent in the amount set forth in
Section C above, no later than the twenty-fifth (25th) day of each month of the Term. The Percentage Rent shall be based on the Gross Sales from the prior month of the Term. 

4.     Condition of Premises. You have inspected the Premises and accept them as is, and we have no obligation to prepare the
Premises for occupancy. You are responsible for any and all installations to prepare the Premises for opening, subject to our approval of such installations, which approval shall not be unreasonably withheld, conditioned or delayed. Neither we nor
our agents have made any representations as to the condition of the Building or the Premises, or any other matter related to the Premises (except as herein expressly set forth). All systems will be delivered in good working order. The taking of
possession of the Premises shall be conclusive evidence that the Premises and the Building were in good and satisfactory condition at such time, except as to latent defects. Any signage shall be installed by Licensee, subject to Licensor’s
prior written approval, which approval shall not be unreasonably withheld, conditioned or delayed. 
 5.     Compliance with Law and
Rules. In the conduct of your business and in your use of the Premises and common areas, you must comply with all insurance requirements and the building Rules and Regulations attached hereto as Exhibit B. You must not do anything that
may increase the insurance premiums we pay. We reserve the right to prescribe the weight and position of all safes and 
 mechanical equipment. You will
give prompt notice to us of any notice you receive of the violation of any law or requirement of any public authority with respect to the Premises, the Building or the use or occupation thereof. We have no obligation to enforce the Rules and
Regulations or covenants in any other occupancy agreement for the Building, and we will not be liable for violation of same by any other occupant of the Building. You agree to follow any reasonable requested protocols established by Licensor in
order to mitigate the spread of COVID-19 as a result of your use of the Premises. You shall comply with all laws applicable to Licensee’s activities including, without limitation, the following: 

(A)     Licensee shall be responsible for obtaining at its expense any licenses or permits necessary in connection with
Licensee’s activities on the Premises, including without limitation, obtaining (and providing a copy of the same to Licensor) any required business licenses and any required permits; and 

(B)     Licensee shall be responsible for collecting and remitting all required sales taxes applicable to the sale of
Licensee’s products, if applicable.  
 6.     Insurance. Licensor and Licensee arc parties to that certain Lease
dated March 18, 2016, by and between Licensor, as Landlord, and Licensee, as Tenant for premises located in the Building (as amended, the “Lease”). Licensee shall, at its full cost and expense, procure and continue in force,
during the term of this Agreement, all insurance required by Tenant under the Lease, such insurance to include the Premises licensed hereunder.

 

 7.     Damages and Repairs. You must take good care of all parts of the Premises,
including installations made by us, and make all repairs, maintenance and replacements during the Term. You must not alter any part without our prior written consent. You are liable for any damage caused by you or those on the Premises with your
permission. 
 8.     Licensor’s Rights and Obligations. (A) We have the right at any time to make changes to the
exterior of the Building and interior of the Building outside of the Premises. We reserve the right to impose controls on access to the Building by your visitors as we deem reasonably necessary for the Building’s security without incurring
liability. 
 (B)     We will perform structural repairs to the Premises (meaning to columns, beams, exterior walls
(excluding windows) or floor slabs) and building systems unless caused by your acts, and we will perform any repairs necessary so the roof remains leak free during the Term, but we are not obligated to perform any capital improvements to the roof.

 (C)     We have no obligation to carry insurance on, and will not be responsible for damage to, the Premises or any
of your property. 
 (D)     We have the right to enter the Premises at reasonable hours and with reasonable advance
notice to show to prospective tenants, licensees, investors, purchasers and mortgagees of the Building. We have the right to perform construction work, improvements and repairs in and around the Building at all times as we deem necessary in our sole
and absolute discretion, but in so doing we will use commercially reasonable efforts not to unreasonably interfere with your operations in the Premises. 

9.     Exculpation. We and our principals, agents, contractors and employees are not liable for any damage or claim with respect to
any injury to persons or any damage to, or loss or destruction of any property of any third party, including without limitation, your employees or your guests, unless due to negligence or willful misconduct on our part. You agree to maintain
insurance to cover such risks. You agree to indemnify, defend and save us harmless against and from all liability, including reasonable attorney’s fees, to third parties arising out of use or occupancy of the Premises or common areas, unless
due to negligence or willful misconduct on our part. If any action or proceeding is brought against us by reason of such claim, upon written notice from us, you may, at your expense, resist or defend such action or proceeding by counsel approved by
us in writing, which approval shall not be unreasonably withheld, conditioned or delayed. In case of fire or other casualty, you will look to your insurance for recovery for any loss or damage to your fixtures, personal property and inventory; you
waive all rights of recovery from us and we are not obligated to repair any damage to the Premises. Notwithstanding anything to the contrary herein, neither Licensor nor Licensee shall be liable under this Agreement for consequential, special or
punitive damages. 

 10.     Reporting. You agree to deliver to us on a monthly basis, within fifteen
(15) days following the end of the previous month, a report of your Gross Sales from your business operations at the Premises, in form and substance reasonably prescribed by, and reasonably acceptable to us. We will use commercially reasonable
efforts to keep such reports confidential, except as required by law. 
 Furthermore, we have the right to disclose such reports to our investors, lenders,
accountants and others with a reasonable “need to know”, subject to the same confidentiality requirements Within sixty (60) days after receiving any gross monthly sales figures, Licensor shall have right to conduct an audit of any
such sales figures. Licensor or its agents, in performing such audit, shall have the right to inspect the records of Gross Sales relating to the Premises at reasonable times during ordinary business hours upon notice. lf any audit by Licensor shows
an error in Licensee’s original monthly sales figure prejudicial to Licensor’s receipt of Percentage Rent reported by Licensee’s statement for the period of the audit, Licensee shall promptly pay to Licensor the amount of the
deficiency with interest thereon. 
 As used in this Agreement, “Gross Sales” means the total sales from or relating to the
Premises when received, no matter how they are paid, including, without limitation, all proceeds from testing taking place at the Premises (whether or not the results of such tests are processed on-or off-site) with the exception of any payment
related to an individual who is tested under the Ginkgo organization as a Ginkgo employee or contractor or a family member of any Ginkgo employee or contractor. 

11.     Default. (A) (i) If you default in fulfilling any of your obligations under this Agreement (other than the obligation to
pay any Rent (which is covered by Section 3 above)); (ii) if you vacate the Premises and/or fail to continuously and uninterruptedly operate the business in the Premises; (iii) if you take advantage of any law for relief from creditors; (iv) if a
petition for relief in bankruptcy or reorganization or arrangement is filed against you; (v) if you dissolve or lack legal capacity to meet your obligations under this Agreement; or (vi) if any execution or attachment shall be issued against you or
any of your property whereupon the Premises shall be taken or occupied by someone other than you, then we shall serve a written 30 days’ notice specifying the nature of said default. Upon the expiration of said 30 days, if such default is not
cured, then this Agreement shall terminate at our election. This Agreement will terminate immediately upon your bankruptcy, at our election. We may enter the Premises at any reasonable time to cure any default by you after notice and the expiration
of the applicable cure period, if any. Bills for expenses incurred by us in connection with any such actions shall be paid by you within 10 business days of demand. 

(B)     In the event of the termination of this Agreement, you shall immediately remove any personal property from the
Premises, immediately pay us an amount equal to all Rent and other sums payable pursuant to this Agreement with respect to the term from the Effective Date through the expiration date, and restore the Premises to the condition described above. We
shall have the right to re-enter the Premises in accordance with this Agreement and applicable law. 

 

 12.     Termination. Upon the expiration or earlier termination of the Term, you must
surrender the Premises, broom clean, in the order and condition received (ordinary wear and damages excepted), with any holes in masonry patched and painted, and emptied of your property and shall pay for our reasonable costs to remove any of your
personal property (including furniture). All property permitted or required to be removed at the end of the Term remaining in the Premises after your removal will be deemed abandoned and may, at our election, either be retained or may be removed
from the Premises, at your expense. 
 13.     Holdover. If possession of the Premises is not
surrendered to us on or prior to the date of termination of this Agreement, we may exercise any rights or remedies we may have hereunder or at law, including collecting any damages suffered by us and arising from your failure to so surrender the
Premises. 
 14.     Liability of Licensor. In the event of any default by us, you shall look only to our estate and interest in
the Premises and Building for the satisfaction of any judgment, and no other property or assets shall be subject to levy, execution or other enforcement procedure for the satisfaction of the same. Neither our members, directors, officers, agents and
employees nor your members, directors, officers, agents and employees shall be liable for the performance of any obligations under this Agreement. 

15. Brokers. Each party represents and warrants to the other that it has not dealt with any broker in connection
with this Agreement. Each party shall indemnify, defend and hold harmless the other from and against any and all claims for commission, fee or other compensation by any person or entity who shall claim to have dealt with such party in connection
with this Agreement and for any and all costs incurred by such party in connection with such claims, including reasonable attorneys’ fees and disbursements. 

16.     Owner-Occupant Relationship. (A) You agree that this agreement should be deemed a “license,” and that upon
termination of this Agreement, or after the end of the Term, we may remove you from the Premises without need for resort to any judicial process. The laws of the state where the Building is located govern this Agreement. You (and we) agree to hereby
waive trial by jury in any action, proceeding or counterclaim brought by either of the parties, except where the law would invalidate such waiver. You will not interpose any counterclaim in any summary proceeding brought by us relating to this
Agreement other than compulsory counterclaims. 
 (B)     We have no other agreement with you, other than the Lease.
Any work in the Premises which may be permitted by us shall be done at your sole cost and expense and in accordance with this Agreement and any additional requirements we deem necessary or desirable. 

(C)     All our rights and remedies herein created or otherwise existing at law or equity are cumulative, and the
exercise of one or more such rights or remedies shall not be deemed to exclude or waive the right to the exercise of any other rights or remedies. All such rights and remedies may be exercised and enforced concurrently and whenever and as often as
deemed desirable. 

 17.     Assignment; Successors. You shall not, either directly or indirectly,
assign, hypothecate, encumber or transfer this Agreement, any interest therein or any interest in the Licensee. You shall not, either directly or indirectly, license or sublicense the use of the Premises in whole or in part. The covenants contained
in this Agreement shall bind and inure to the benefit of you and your respective heirs, distributees, executors, administrators, and successors. 
 18.
    Notices. Notice under this agreement shall be delivered by hand or sent by recognized overnight courier service to the parties at the addresses set forth on page one of this Agreement. Notices shall be deemed effective,
if delivered by hand, upon delivery and, if sent by courier service, one business day after such notices are deposited with the courier service. 
 19.
    Subordination. This Agreement is subject and subordinate to all ground or underlying leases and to all mortgages which may now or hereafter affect any of the Building and to all renewals, modifications, consolidations,
replacements and extensions of any such underlying leases and mortgages. 
 20.     Eminent Domain; Casualty. In the event that
some or all of the Premises arc taken for any public or quasi public use or purpose by any lawful power or authority by the exercise of the right of condemnation or eminent domain, this Agreement shall terminate on the date of such taking. You shall
have no claim for the value of any unexpired term and assign to us your entire interest in any such award. In the event of a fire or other casualty, we shall be responsible for restoring the structural components of the Building and base building
systems, and you shall be responsible for restoring the Premises, fixtures and personal property. Notwithstanding the foregoing, we will have the right to terminate this Agreement if there is substantial damage to the Building, whether or not the
Premises are damaged, and we elect not to restore the same. In that event, you must surrender the Premises on the date specified by us and you will have no further rights hereunder. 

21.     Intentionally Deleted. 

22.     Jurisdiction and Service of Process. (A) You hereby irrevocably: 

(1)     submit to the jurisdiction of the state courts and federal courts in the state which the Building is located for
the purposes of each and every suit, action or other proceeding arising out of or based upon this Agreement or the subject matter hereof brought by us; and 

(2)     waive, and agree not to assert, by way of motion, as a defense, or otherwise, in any such suit, action or
proceeding brought in any such court, any claim that you are not subject personally to the jurisdiction of the above-named courts, that your property is exempt or immune from attachment or execution, that the suit, action or proceeding is brought in
an inconvenient forum, that the venue of the suit, action or proceeding is improper or that this Agreement or the subject matter hereof may not be enforced in or by such court, and further agrees to waive, to the fullest extent permitted under
applicable law, the benefit of any defense that would hinder, fetter or delay the levy, execution or collection of any amount to which we or our successors or assigns arc entitled pursuant to the final judgment of any court having jurisdiction.

 

  
 4 

 
 (B)     You represent and warrant to us that you are duly organized,
validly existing and in good standing under the laws of the state where the Building is located, with full power and authority to enter into and perform this Agreement; you have received all approvals necessary for the execution and delivery of this
Agreement and performance of your obligations hereunder and this Agreement constitutes the legal, valid and binding obligation of you, enforceable against you in accordance with its terms. Neither the execution and delivery of this Agreement nor the
performance by you of your obligations hereunder will violate, be in conflict with, result in a breach of, or constitute (with due notice or lapse of time, or both) a default under any applicable law or under any agreement or order binding upon you,
or require any consents which have not been obtained. 
 23.     Intentionally Deleted. 

24.     Publicity. You agree not to make or provide any public statement, press release or other public disclosure
related to this Agreement and/or the opening of Licensee’s business at the Building (including, without limitation, by means of statements, press releases or disclosures displayed or accessible electronically, on the internet and/or on social
media, such as, by way of example only, Facebook, Twitter and lnstagram) without the prior written consent of Licensor, which consent shall not be unreasonably withheld, conditioned or delayed. These restrictions on disclosure shall survive the
termination or expiration of this Agreement. 
 All announcements, advertisements, emails, social media, and other correspondence by Licensee related to
Licensee’s business at the Premises will mention the name of Licensor’s property as the host location and, when appropriate, will include the Licensor’s logo. Any such social media posts by Licensee will tag and/or geotag
Licensor’s corresponding social media accounts (including, but not limited to, Facebook and lnstagram) and will utilize the handles and hashtags provided by Licensor. 

25.     Counterparts. This Agreement may be executed in counterparts all of which shall be considered on and the same
agreement and shall become effective when one or more counterparts have been signed by each of the parties, it being understood that all parties need not sign the same counterpart. This Agreement may be executed by facsimile or e-mail, and any
signature so given shall be deemed an original. 
 26.     OFAC. Licensor and Licensee each represent and warrant to the other
(for themselves, only) that each is currently in compliance with, and shall at all times during the term of this Agreement (including any extension thereof) remain in compliance with, the regulations of the Office of Foreign Asset Control
(“OFAC”) of the Department of the Treasury (including those named on OFAC’s Specially Designated and Blocked Persons List) and any statute, executive order (including the September 24, 2001, Executive Order Blocking Property
and Prohibiting Transactions with Persons Who Commit, Threaten to Commit, or Support Terrorism), or other governmental action relating thereto. Licensee shall provide documentary and other evidence of Licensee’s identity and ownership as may be
reasonably requested by Licensor at any time to enable Licensor to verify identity or to comply with any legal requirement.

 27.     Miscellaneous. Except as otherwise required by law, you agree not to
disclose the terms of this Agreement to anyone other than your attorneys, accountants, officers, directors, investors and lenders. Time shall be of the essence with respect to all of the terms and conditions of this Agreement. In the event that we
engage an attorney to enforce your obligations under this Agreement, you will be responsible for paying the amount of any reasonable attorneys’ fees and costs we incur. No estate passes to Licensee under this Agreement, and Licensee shall have
a license only. This Agreement sets forth all the covenants, promises, agreements, conditions and understandings between us concerning the Premises. 

28.     Prime Lease. Licensee recognizes and acknowledges the existence of the Prime Lease (as hereinafter defined) and that this
Lease is a sublease of a portion of Licensor’s leasehold estate created by the Prime Lease. The termination of the Prime Lease for any reason whatsoever shall never constitute a default by Licensor hereunder nor shall such termination entitle
Licensee to terminate this Lease or the payment of any Rent or other sums due by Licensee hereunder. Licensee further agrees that this Lease is subject to all of the terms and provisions of the Prime Lease and hereby agrees to be bound by provisions
thereof, including but not limited to the provisions relating to employment and non-discrimination. By execution hereof, Licensee hereby acknowledges that it has received a copy of all provisions of the Prime Lease relating to employment and
non-discrimination all as set forth in the Prime Lease. Prime Lease shall mean that certain long term lease agreement dated January 30, 2007 by and between The Economic Development and Industrial Corporation of Boston, a corporation organized under
the laws of the Commonwealth of Massachusetts, as Prime Lessor and CV Drydock Avenue LLC, as Prime Lessee, as amended by First Amendment dated January 21, 2015, covering the Building and certain real property on which the Building is situated, as
the same may be further amended from time to time. 

 

  
 5EX-10.36

 Exhibit 10.36 

SUPPLY AGREEMENT 
 This Supply Agreement
(this “Agreement”) is entered into as of March 2, 2018, but is effective as of March 1, 2018 (the “Effective Date”), by and between Twist Bioscience Corporation, a Delaware corporation with offices at 455
Mission Bay Blvd South, San Francisco, CA 94158 (“Twist”), and Ginkgo Bioworks, Inc., a Delaware corporation with offices at 27 Drydock Avenue, 8th Floor, Boston, Massachusetts 02210 (“Customer”). 

1. RELATIONSHIP 
 1.1 General. 

(a) Transactions Generally. During the Supply Term (as defined below), Customer may issue a blanket purchase order under which, from time to time,
subject to the terms of this Agreement, Customer may issue individual orders (each a “Transaction”) for (i) synthesis of certain designated DNA products (“Clonal Products” &
“Non-clonal Sequences” as defined below) based on Sequence Submissions as defined below (“Deliverables,” and each synthesized sequence individually, a
“Deliverable”), or (ii) any Additional Services (as defined in Section 1.1(d) below). Twist will use all commercially reasonable efforts to confirm acceptance of any Transactions within [***] of receipt of such
Transaction, subject to the terms of this Agreement. The Deliverables consist of: 
  

	 	(i)	 “Clonal Products” which consist of the following: 

 

	 	(a)	 “300-1,000bp Clonal Genes” which are defined as
clonally perfect genes greater than 300 base pairs but less than or equal to 1.0 kilobase pairs (“kbp”) in length; 

  

	 	(b)	 “Short Clonal Genes” which are defined as clonally perfect genes greater than 1.0 kbp but less
than or equal to 1.8 kbp in length; 

  

	 	(c)	 “Clonal Genes” which are defined as clonally perfect genes greater than 1.8 kbp but less than
or equal to 3.2 kbp in length; and 

  

	 	(d)	 “Long Clonal Genes” which are defined as clonally perfect genes greater than 3.2 kbp but less
than or equal to 5 kbp in length. 

  

	 	(ii)	 “Non-clonal Sequences” which consist of the following:

  

	 	(a)	 “Non-clonal Sequences (1.8kB)” which are defined as
linear DNA greater than 300 base pairs but less than or equal to 1.8 kbp in length with a maximum error rate of [***] including adapter sequences. 

  

	 	(b)	 “Non-clonal Sequences (3.2kB)” which are defined as
linear DNA greater than 1.8 kbp base pairs but less than or equal to 3.2 kbp in length with a maximum error rate of [***] including adapter sequences. 

(b) Deliverables. If Customer desires that Twist create any Deliverables, Customer shall provide Twist with genetic sequences to be synthesized (each a
“Sequence Submission”) and a corresponding Transaction consistent with this Agreement. If any such Sequence Submission requests Deliverables that do not meet the Sequence Guidelines (as defined below in Section 1.5), upon
receipt of any such Sequence Submission, Twist will use commercially reasonable efforts to analyze and score such Sequence Submission pursuant to the Sequence Guidelines. Upon completion of such analysis, and in no event later than [***]
after receipt of any such Sequence Submission, Twist will notify Customer of the results in writing, and Customer shall have the opportunity to, at Customer’s discretion, revise such Sequence Submission and
re-submit the Sequence Submission to Twist, to confirm its desire to include such Sequence Submission in the Transaction if it has a score of [***], or to remove/cancel such Sequence Submission from the
Transaction. The foregoing process may be repeated as many times as desired by Customer. Twist shall be obligated to accept any Transactions with respect to Sequence Submissions that meet the Sequence Guidelines, and with respect to any other
Sequence Submissions that have a score of [***] as determined in accordance with the process stated above, subject to Section 1.5; provided that the Deliverables ordered in such 

  

	‡	 Certain confidential information contained in this Exhibit has been omitted because it is (i) not
material and (ii) of the type that the registrant treats as private or confidential. 

 
Transaction do not exceed the applicable maximum length restrictions described in the following sentence. Customer agrees that Deliverables will not exceed the maximum length described in the
definition of each Deliverable in Section 1.1 (a) above), provided that Twist may in its discretion offer to increase the permitted number of base pairs in Deliverables by written notice to Customer (in which case the definitions above shall be
automatically modified to reflect such increase for such particular Transaction). Twist shall notify Customer of the acceptance (or partial acceptance) of each Transaction within [***] of receipt of such Transaction with respect to Sequence
Submissions meeting the Sequence Guidelines and within [***] of receipt by Twist of Customer’s confirmation to proceed with such Sequence Submission in light of the relevant score determination of [***] as set forth above with
respect to Sequence Submissions not meeting the Sequence Guidelines and not canceled by Customer as provided above. Twist will initiate synthesis when new Transactions totaling at least [***] have been placed (“Minimum Size
Order”). High Priority Clonal Sequences are exempt from the Minimum Size Order as described below. Customer may submit individual Transactions for any number of Deliverables. For clarity, the distinction between Minimum Size Order and
Transaction gives Customer the ability to group related Deliverables for tracking purposes and to ensure minimum yields (as defined below under Reasonable Efforts) for the Transaction and gives Twist the ability to aggregate efficient batches for
manufacturing. Notwithstanding Section 8.6, the ordering and scoring process described above may be conducted by the parties via email or other electronic means as agreed by the parties. Twist will use commercially reasonable efforts to create
the Deliverables under accepted Transactions and to produce and deliver to Customer such Deliverables, subject to Sections 1.5 and 1.8, and to ensure that the Deliverables conform to the relevant Transaction, all in accordance with the terms
and conditions of this Agreement, the Transaction, and the Sequence Submission. In the event that, despite its commercially reasonable efforts, Twist determines that its efforts to synthesize any Sequence Submission have failed, Twist will promptly
communicate such determination to Customer. 
 (c) High Priority Sequences. The parties agree that Twist will use a first pass protocol to synthesize
Deliverables for Transactions it has accepted. If Twist delivers at [***] of the Non-clonal Sequences in a given Transaction or [***] of Clonal Products in a given Transaction, it may, at its
discretion and following written notice to Customer, abandon attempts to construct the remaining Deliverables in the Transaction, provided that any ordered and undelivered Deliverables will still count towards the Quarterly Minimums (defined below).
Customer may order Clonal Products as high-priority sequences (“High Priority Clonal Sequences”), and such High Priority Clonal Sequences will be put on highest priority on each production step and include [***] which should
yield a final pass rate up to [***]. Customer shall clearly designate in writing any High Priority Clonal Sequences in the Transaction and the special pricing for such High Priority Clonal Sequences specified in Section 2 below shall
apply. No more than [***] of orders in any single month may be designated as High Priority Clonal Sequences. High priority Clonal Sequences will count towards the Minimums (defined below). 

(d) Additional Services. Customer may request that Twist perform additional services, which may include using a vector provided by Customer (a
“Customer Vector”) to provide the Deliverables (“Additional Services”), in each case subject to the terms of this Agreement and (except for using a Customer Vector to provide Deliverables) subject to Twist’s
prior written agreement to perform such Additional Services (not to be unreasonably withheld so long as such Additional Services are substantially related to Twist’s other activities hereunder and Twist has the ability, expertise and capacity
to perform them), provided that if the fees for such Additional Services are not provided Customer and Twist shall agree on the fees in writing for such Additional Services prior to Twist performing any such Additional Services and Twist will then
use commercially reasonable efforts to perform such Additional Services. The parties agree to a [***] for each new customer vector that must be validated by Twist. 

(e) Modification of Transactions. Except as expressly provided herein, Customer may not cancel any Transactions once accepted by Twist. In connection
with ordering and delivering services and products hereunder, Twist and Customer may employ their standard forms, but no additional terms contained in any Transaction or other form shall bind either party or be construed to modify or amend the terms
of this Agreement and, in the event of any conflict with the terms hereof, this Agreement shall control. 
 1.2 Cooperation; Customer
Materials. Customer hereby grants to Twist a non-exclusive, non-transferrable license during the Term to use and develop the sequences and other information provided
in the Sequence Submission and the Customer Vectors (collectively, the “Customer Materials”) for the sole purpose of providing the services ordered by Customer hereunder (including without limitation to synthesize Deliverables and
perform Additional Services). Customer acknowledges that Customer’s timely cooperation and provision of complete and accurate information (“Cooperation”) is essential to the performance of the services hereunder. If Customer
fails to provide Cooperation to Twist, Twist will not be liable for any deficiency or delay in performing any services to the extent arising from a failure to provide Cooperation. 

 1.3 Minimum Volume Commitment. 

(a) Customer agrees to place Transactions for Deliverables meeting the Sequence Guidelines or otherwise meeting the criteria for acceptance (including the kbp
limits) as provided in Section 1.1(b) (“Acceptable Transactions”) for at least the quarterly minimum volume commitments as provided in Exhibit A, attached hereto and incorporated herein, (the “Quarterly
Minimums”). Customer agrees to place Transactions for approximately One Billion, Three Hundred Million (1,300,000,000) base pairs of DNA or at least [***] prior to the end of the Supply Term (collectively, the “Total
Minimum” and with the Quarterly Minimums, the “Minimums”), where the Total Minimum is subject to all adjustments (as defined and further described in this Section 1.3). Customer will provide to Twist a non-binding, rolling three (3) month forecast of anticipated Product demand by the 15th of each month. The distribution of products that makes up a Quarterly Minimum for a future quarter may be increased
or decreased by no more than [***] at Customer’s sole discretion, so long as Customer provides prior written notice to Twist of such adjustment at least one quarter in advance; adjustments of up to [***] may be made at
Customer’s sole discretion so long as Customer provides prior written notice to Twist at least two quarters in advance. The Parties acknowledge that quarterly product demand may vary; provided however that prices provided herewith reflect a
maximum of [***] of Deliverables ordered being comprised of Long Clonal Genes. 
 (b) The Minimums will be modified under the following scenarios:

  

	 	(i)	 for any quarter that the Long Clonal Genes product is not available, the Minimum Volume Commitment is reduced
by the volume listed in the table below for that product in that quarter; 

  

	 	(ii)	 for any quarter in which an Application Program Interface feature (defined in Section 1.10) is not
available for a product, the Minimum Volume Commitment is reduced by [***] of the volume listed in the table below for that product in that quarter; 

  

	 	(iii)	 for any Deliverables where average Standard TAT (as defined in Section 1.7) measured over two consecutive
quarters is more than [***] than Standard TAT, Customer’s commitment for that product for the following two quarters shall be reduced by [***]; and 

 

	 	(iv)	 in the event average yield for a Clonal Product measured over two consecutive quarters is greater than
[***], Customer’s commitment for that Clonal Product for the following two quarters shall be reduced by the corresponding number of genes. 

For the avoidance of doubt, any and all Transactions placed by Customer in accordance with this Agreement on or after the beginning of the Supply Term and
before the expiration of the Supply Term and meeting the Sequence Guidelines, regardless of when such order is delivered or not delivered as further provided herein, will be applied against the Minimums. 

(c) If, within the [***] after the end of each of the [***] quarters (i.e., 3 month period) of the Supply Term, Customer determines
that the actual yield for Clonal Products exceeds [***] aggregated across the preceding quarter, then Customer shall provide Twist written notice of such occurrence (a “High Yield Event”). In the event of a High Yield Event
Twist will, upon request by Customer, adjust down the Quarterly Minimums over the aggregate of the next immediate succeeding quarter to reflect such overage from the previous quarter’s High Yield Event “(High Yield
Adjustment”), provided that in no case will the Quarterly Minimums be reduced below [***] of the original Quarterly Minimum for such month. 

(d) In the event that Customer fails to place sufficient acceptable Transactions in accordance with the Agreement for the Minimums measured every 6 months from
the start of the agreement, Customer agrees to pay Twist an amount equal to [***] per Deliverable times the difference between the scheduled volume in Exhibit A (including any modifications as described above) and the amount actually ordered
during such 6-month period (a “Shortfall Payment”) within [***] of Twist’s invoice therefor. 

1.4 Sequence Guidelines. Twist will provide Customer with its current sequence guidelines (the “Sequence Guidelines”). In the
event that Twist, in its sole discretion, issues an updated set of Sequence Guidelines, this Agreement will be amended to include such updated Sequence Guidelines. For clarity, such Sequence Guidelines shall at all times be consistent with those
offered generally to Twist’s other customers for similar services. However, if such Sequence Guidelines are reasonably determined by Customer to be more restrictive than the then-current 

 
Sequence Guidelines under this Agreement, then Customer may reduce the Quarterly Minimums proportionally to the degree that that Sequence Guidelines become more restrictive. Any updates shall
apply to Transactions placed more than ten (10) days after Customer’s receipt of the updated Sequence Guidelines. Sequence Guidelines may be in the form of an algorithm or as a descriptive list of guidelines. The initial Sequence
Guidelines are as follows: 
 (a) To be in conformance with the Sequence Guidelines, the Sequence Submission must contain: [***] 

(b) [***] 
 Twist will score each received Sequence Submission
for complexity on a scale of 1 (simple) – 5 (very complex) using its algorithms. 
 Sequence Guidelines for
Non-clonal Sequences are the same as for Clonal Products. Non-clonal Sequences include a short standardized adapter sequence on each end. Twist has their own preferred
adapter sequence however if Customer requires their own adapter sequence they must provide Twist the opportunity to verify the Customer adapter sequence in Twist processes. 

In addition, Customer will provide Twist with prior written notice of any Transaction that Customer believes, to the best of its knowledge, meets the
definition of “Toxic Sequences” as described in Exhibit B, where such Exhibit B may be updated from time to time by Customer at its discretion or by the Parties mutual agreement. 

The Sequence Guidelines and all related algorithms are Confidential Information of Twist. 

1.5 Termination of a Transaction. Twist may terminate a Transaction, in Twist’s sole discretion and upon prior written notice to Customer,
if Twist determines that such cancellation is reasonably necessary for biosecurity, biosafety, patent infringement, including without limitation any export restrictions. No terms other than as provided herein will be binding on either party. 

1.6 [***] 
 1.7 Delivery; Inspection. 

(a) Twist will ship the Deliverables to Customer at the address provided in the Transaction Ex Works (Incoterms 2010). All Deliverables will be shipped as
follows: 
 Quarters 1-4: [***] 

Quarters 5-8: [***] 

Quarters 9-12: [***] 

Quarters 3-16: [***] 

The first number in each cell indicates the normal number of business days for delivery after purchase order acceptance. The second number in each cell
indicates the outside number of business days after purchase order acceptance (“Maximum TAT”). After the Maximum TAT, Customer may choose to cancel the order at no cost but, for clarity, the ordered sequences not delivered by the
Maximum TAT will still count towards the Minimums. 
 To smooth demand on capacity, Customer may submit a large Transaction of Deliverables that Customer
wishes to be exempt from turnaround time requirements provided herein (a “Low Priority Transaction”). Twist will acknowledge receipt of Low Priority status within [***]. Customer may also change the priority status of
existing Transactions depending upon Customer’s requirements. Proposed changes in the status of existing Transactions shall be discussed by the parties at the next scheduled weekly meeting between Twist and Customer and mutually agreed to by
the parties in writing. Any existing Transaction for which its priority status is changed from a lower priority to a higher priority will have the turnaround time of the new priority effective [***] from the date the change in priority was
agreed to by the parties. 

 The provisions of this Section 1.7(a) shall be Customer’s sole and exclusive remedy for
Twist’s failure to timely deliver the Deliverables. All deliveries will be via overnight courier. [***] 
 (b) All Deliverables will be delivered
in 96- or 384-well plates along with an associated plate map. Clonal Products can be delivered in Twist’s in-house
maintenance vector, or in a Customer Vector, at Customer’s discretion and as noted in the relevant Transaction. The minimum acceptable yield for Clonal Products is [***] but Customer may accept lower yields in its sole discretion. The
minimum acceptable yield for Non-clonal Sequences is [***] of size-verified DNA but Customer may accept lower yields in its sole discretion. 

(c) Twist will ship the Deliverables in a single shipment upon completion of the relevant Transaction or, at Customer’s written request, whenever at least
[***] Deliverables are ready to ship. 
 (d) If Customer reasonably determines that any Deliverables do not materially comply with the relevant
Sequence Submission, Customer shall have [***] from receipt of such Deliverables (the “Test Period”) to provide Twist with written notice specifying how the Deliverables fail to conform and, if requested by Twist, return the non-conforming Deliverables to Twist. Following the notice of non-conformity, unless Twist reasonably determines that the Deliverables do in fact conform, Twist shall, as
directed by Customer, [***]. If Customer fails to provide written notice of non-conformity during the Test Period, the relevant Deliverables will be deemed accepted. The foregoing shall be
Customer’s sole and exclusive remedy for any Deliverables that fail to conform. 
 1.8 Restrictions on Deliverables. 

(a) Twist’s standard cloning plasmids serve only as carriers for the de novo synthesized DNA only and shall not be used for any other purpose, including
without limitation for expression. Twist makes no representation or warranty that the combination of these plasmids with specific de novo synthesized DNA will not infringe any third party patents or rights. Twist does not accept responsibility for
the correctness of the vector backbone sequence, the presence or absence of restriction sites, antibiotic markers, promoters or other sequence elements in the vector backbone that were not created by Twist. 

(b) Deliverables are intended for research use only and not for use in human and/or animal diagnostic procedures, and Customer agrees to follow any reasonable
applicable use restrictions that are provided to Customer by Twist in writing. Should Customer use such Deliverables for any purpose other than internal research, Customer is solely responsible for qualifying such Deliverable for such use and
obtaining any intellectual property rights that might be required, and Twist shall have no liability for such use. 
 1.9 Export Control.
Deliverables may be subject to United States, European Union and local export-control laws and regulations. Customer may not, directly or indirectly, sell, export, re-export, transfer, divert, or otherwise
dispose of any such Deliverables or related information (including products derived from or based on the Deliverables or information) to any destination, entity, or person prohibited by United States, European Union or local laws or regulations.
Upon written request from Twist, Customer shall promptly provide Twist with information that Customer processes or to which it has access as needed for completion of exportation or importation governmental processes, including licensing, with
respect to Twist’s performance under this Agreement. 
 1.10 Application Program Interface (“API”). Twist will provide to
Customer a fully automated interface for placing Transactions dependent on Customer signing a separate API agreement for use. The API will enable Customer to validate, score, quote, and place Transactions for all product categories programmatically.
Furthermore, the API will enable Customer to query the status of placed Transactions and receive information about success or failure of the Deliverables within the Transaction at multiple points in the synthesis process. The API is expected to be
fully operational by the commencement of the Agreement. Within [***] of the commencement of the Agreement, the API will support customer vector setup. 

1.11 [***] 
 1.12 Project Management. At
Customer’s option, Twist will assign a dedicated project manager to handle Customer orders, Customer Vector onboarding and order fulfillment. 
 2.
FEES AND TAXES 
 2.1 In consideration of Twist’s performance of the services pursuant to this Agreement, Customer will pay to Twist the fees
provided below (the “Fees”). 

 For Deliverables: [***] 

Unclonable Genes 
 Upon agreement between Customer and
Twist, Twist will supply “in-process” Non-clonal Sequences for Deliverables that are deemed “unclonable” at a price of [***]. Non-clonal Sequences will meet normal specifications for that product category. 
 2.2 Twist will invoice Customer
upon shipment of the Deliverables. All undisputed invoiced amounts shall be due [***] from the date of invoice. If Customer disputes any amount for which Twist seeks payment, Customer shall provide Twist with prompt written notice of the
amount disputed and the basis therefor, and the parties will work together in good faith to resolve the matter. Overdue payments will be subject to interest at the rate of [***] The Fees are nonrefundable except as expressly set forth herein.
Customer will, in addition to the other amounts payable under this Agreement, pay any and all applicable customs, duties, sales, use, value added or other taxes, federal, state or otherwise, however designated, which are levied or imposed by reason
of the transactions contemplated by this Agreement (excluding taxes based on Twist’s net income). 
 3. CONFIDENTIALITY 

3.1 Duty. Each party will retain in confidence the non-public information and know-how disclosed or otherwise made available by the other party pursuant to this Agreement which should reasonably be understood to be confidential by a reasonable recipient (the “Confidential
Information”). For clarity, the Twist Materials (as defined in Section 4.2 below) shall be Twist’s Confidential Information and the Customer Materials shall be Customer’s Confidential Information. Notwithstanding anything to
the contrary herein, Customer agrees that Twist may, during and after the Term, use any generally applicable data or information developed by Twist or acquired from a third party while performing the services herein on an aggregated, non-Customer identifiable basis, provided that the foregoing shall not entitle Twist to use or disclose the Customer Materials or Customer Confidential Information except to provide the services herein and produce
the relevant Deliverables. The receiving party hereby agrees to: (a) preserve and protect the confidentiality of the disclosing party’s Confidential Information; (b) refrain from using the disclosing party’s Confidential
Information except as contemplated herein; and (c) not disclose such Confidential Information to any third party except to employees, agents and subcontractors as is reasonably required in connection with the performance of this Agreement or
the exercise of rights hereunder (and only subject to binding use and disclosure restrictions at least as protective as those set forth herein). The receiving party agrees to immediately notify the disclosing party of any unauthorized disclosure or
use of any of the disclosing party’s Confidential Information and to assist the disclosing party in remedying such unauthorized use or disclosure by taking such steps as are reasonably requested. Upon the disclosing party’s request or
within thirty (30) days after termination of this Agreement, the receiving party will return to the disclosing party or, on the disclosing party’s request, destroy all of the disclosing party’s Confidential Information and materials
containing any Confidential Information of the disclosing party in the receiving party’s possession. 
 3.2 Exceptions. Notwithstanding
the foregoing, the receiving party may disclose Confidential Information of the other party which is: (a) already publicly known without breach of this Agreement; (b) discovered or created by the receiving party without use of, or
reference to, Confidential Information provided by the disclosing party, as shown in the receiving party’s written records; or (c) otherwise known to the receiving party through no wrongful conduct of receiving party. If the receiving
party is required by a governmental authority or by order of a court of competent jurisdiction to disclose any Confidential Information of the disclosing party, such disclosure shall not be a violation of this Agreement provided that the receiving
party shall give the disclosing party prompt written notice of such requirement or order and provide reasonable assistance to the disclosing party to enable the disclosing party to seek a protective order or otherwise prevent or restrict such
disclosure. Moreover, the receiving party may disclose any Confidential Information hereunder to any court of competent jurisdiction as reasonably required to resolve any dispute between the parties hereto. 

3.3 Remedies. Each party agrees and acknowledges that any breach or threatened breach of this Section 3 may cause irreparable injury to the
disclosing party and that, in addition to any other remedies that may be available, in law, in equity or otherwise, the disclosing party will be entitled to seek injunctive relief against the threatened breach of this Agreement or the continuation
of any such breach by the receiving party, without the necessity of proving actual damages or posting any bond, in addition to any other rights or remedies provided by law. 

 4. PROPRIETARY RIGHTS 

4.1 Customer Materials. The parties acknowledge that Customer will retain ownership of the Customer Materials. 

4.2 Twist Materials. The parties acknowledge that Twist will retain ownership of any and all gene synthesis technology, inventions, works of
authorship, documents, diagrams, data, drawings, information, concepts, designs, algorithms, software, ideas, know-how, processes, protocols and other technology materials owned or developed by Twist in
connection with its performance of any services pursuant to this Agreement (other than the Deliverables, Customer Vectors and any other items listed above to the extent that they cannot exist and be used without use or disclosure of Customer
Confidential Information) including any updates, derivatives, modifications, or improvements thereof or thereto (collectively, “Twist Materials”). The Twist Materials shall include any Twist vectors. 

4.3 Deliverables. Subject to the terms and conditions of this Agreement, Customer shall own all right and title to the Deliverables, provided,
however that such rights in the Deliverables shall not include any rights in or to the Twist Materials, provided that Twist will grant and does hereby grant to Customer and its Affiliates (as defined in Section 8.7 below) a perpetual, non-exclusive, fully paid-up worldwide, sublicensable license to use Twist Materials incorporated into the Deliverables, in each case solely as incorporated into the
Deliverables and subject to the terms and conditions of this Agreement. 
 4.4 Reservation of Rights. Except as otherwise expressly provided
herein, nothing in this Agreement will be deemed to grant, directly or by implication, estoppel, or otherwise, any right or license with respect to a party’s intellectual property or materials, and each party retains all right, title, and
interest in such property and materials, including without limitation (a) patents, patent applications, patent disclosures and inventions (whether patentable or not), (b) trademarks, service marks, and registrations and applications for the
registration thereof, together with all goodwill associated therewith, (c) copyrights and copyrightable works (including computer programs), and registrations and applications for the registration thereof, and (d) trade secrets, know-how and other confidential and proprietary information. 
 5. WARRANTIES; DISCLAIMER AND LIMITATION OF LIABILITY

 5.1 Customer Warranties. Customer represents and warrants that (a) Customer has the right to provide and license the Customer
Materials as provided in this Agreement, including without limitation the right to allow Twist to create the Deliverables as provided herein, (b) Twist’s use of the Customer Materials as provided herein will not violate any contract, or
applicable law or regulation, and (c) to Customer’s knowledge, the Customer Materials do not infringe on or violate any third-party intellectual property rights. 

5.2 Disclaimer and Limitation of Liability. EXCEPT AS EXPRESSLY PROVIDED IN THIS AGREEMENT, TWIST MAKES NO OTHER REPRESENTATIONS OR WARRANTIES,
EXPRESS, IMPLIED, STATUTORY, OR OTHERWISE, WITH RESPECT TO ANY SERVICES PROVIDED UNDER THIS AGREEMENT, DELIVERABLES, THE API, ADDITIONAL SERVICES, OR ANY OTHER MATERIAL PROVIDED HEREUNDER. TWIST SPECIFICALLY DISCLAIMS ALL OTHER WARRANTIES, EXPRESS
AND IMPLIED, INCLUDING WITHOUT LIMITATION THE IMPLIED WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT, THOSE WARRANTIES ARISING FROM A COURSE OF DEALING OR USAGE OR TRADE, OR ANY WARRANTIES REGARDING NON-TWIST ITEMS, AND ALL SUCH WARRANTIES ARE HEREBY EXCLUDED TO THE FULLEST EXTENT PERMITTED BY LAW. EXCEPT AS EXPRESSLY PROVIDED HEREIN, ANY SERVICES PROVIDED UNDER THIS AGREEMENT, DELIVERABLES, THE API, AND
ADDITIONAL SERVICES ARE PROVIDED ON AN “AS IS” AND “AS AVAILABLE” BASIS. IN NO EVENT WILL TWIST’S LIABILITY ARISING UNDER THIS AGREEMENT EXCEED THE FEES PAID BY CUSTOMER TO TWIST HEREUNDER IN THE TWELVE (12) MONTHS
PRECEDING THE CLAIM UNDER WHICH SUCH LIABILITY AROSE. IN NO EVENT WILL EITHER PARTY BE LIABLE UNDER THIS AGREEMENT FOR ANY CONSEQUENTIAL, INCIDENTAL, SPECIAL, INDIRECT, PUNITIVE OR EXEMPLARY DAMAGES, INCLUDING WITHOUT LIMITATION LOST PROFITS,
REVENUE, GOODWILL, OR COSTS OF PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES, OR FOR ANY CLAIM OR DEMAND BY ANY THIRD PARTY, HOWEVER CAUSED AND (TO THE FULLEST EXTENT PERMITTED BY LAW) UNDER ANY THEORY OF LIABILITY (INCLUDING NEGLIGENCE) EVEN IF SUCH
PARTY HAS BEEN ADVISED OF THE POSSIBILITY OF SUCH DAMAGES. THE PARTIES AGREE THAT THE AMOUNTS PAYABLE HEREUNDER ARE BASED IN PART ON THESE LIMITATIONS, AND THESE LIMITATIONS WILL APPLY NOTWITHSTANDING ANY FAILURE OF ESSENTIAL PURPOSE OF ANY LIMITED
REMEDY. 

 6. INDEMNIFICATION 

6.1 Twist will defend or settle, at its own expense, any third-party action against Customer or its officers, directors, employees, agents, successors,
or assigns to the extent based on a claim that any Twist Materials infringe or otherwise violate such third-party’s U.S. trade secret or U.S. copyright, and will pay such damages or costs as are finally awarded against Customer attributable to
such claim. Should any Twist Materials become, or in Twist’s opinion be likely to become, the subject of such an infringement claim, Twist may, at its option, (a) procure the right to use the Twist Materials; (b) replace or modify, in
whole or in part, the Twist Materials to make it non-infringing; or (c) terminate the Agreement and refund the Fees paid for any affected Deliverables supplied to Customer. Twist assumes no liability
under this Section 6.1 for: (i) the Deliverables, (ii) any compliance with the Sequence Submission; or (iii) any Customer Materials or Twist’s use of such Customer Materials as provided in this Agreement; and Customer will
indemnify, defend, and hold harmless Twist and its officers, directors, employees, agents, successors, and assigns against any damages, losses, and expenses (including reasonable attorneys’ fees) arising from any third-party action against
Twist or its officers, directors, employees, agents, successors, or assigns to the extent based on a claim that services provided under this Agreement, Deliverables, or Additional Services infringe or otherwise violate such third-party’s
intellectual property or other proprietary rights due to any of (i) through (iii) (inclusive). 
 6.2 The indemnification obligations set forth
in Section 6.1 are contingent upon the indemnified party: (a) promptly notifying the indemnifying party of the claim for which indemnification is sought; (b) giving the indemnifying party sole control of the defense and settlement of
the action, provided that any settlement that imposes any material obligation on the indemnified party will require the indemnified party’s prior written consent, not to be unreasonably withheld or delayed; and (c) giving the indemnifying
party all reasonable cooperation and assistance in its defense or settlement of the action at the written request and expense of the indemnifying party. THIS SECTION 6 SETS FORTH TWIST’S ENTIRE LIABILITY AND OBLIGATION, AND CUSTOMER’S
SOLE REMEDY, FOR ANY CLAIM OF INFRINGEMENT OR VIOLATION OF ANY INTELLECTUAL PROPERTY RIGHTS HEREUNDER. 
 7. TERM AND TERMINATION 

7.1 Term. Unless earlier terminated as provided in this Section 7, this Agreement will be effective as of the Effective Date and will
continue thereafter until the end of the Supply Term (the “Term”). The “Supply Term” shall start on March 1, 2018 and shall end forty eight (48) months after the Effective Date. 

7.2 Termination by Mutual Agreement. At any time during the Term, the Agreement may be terminated upon the mutual written consent of the Parties.

 7.3 Termination for Specified Change in Control. Twist shall provide Customer [***] prior written notice (a “Specified Change in Control
Notice”) of any Specified Change in Control (as defined below). Customer may terminate this Agreement in its sole and absolute discretion upon written notice given to Twist not later than [***] after the receipt of such Specified Change in
Control Notice. For purposes of this Agreement, “Specified Change in Control” means the consummation of a merger or sale of Twist or of substantially all of the assets of Twist to which this Agreement applies, in each case, with or
to a Specified Party or an Affiliate thereof; provided, that a Specified Change in Control shall not include any bona fide investment transaction, in which Twist issues shares of its capital stock to the investor(s) participating in such bona
fide investment transaction, and (ii) “Specified Party” means [***] 
 7.4 Termination for Material Breach. Either party may
terminate this Agreement for the material breach of the other party upon sixty (60) days’ prior written notice to such other party describing such breach in reasonable detail and upon providing an opportunity to cure for the breaching
party before the end of such 60-day period (and in the case of such a cure, this Agreement shall remain in full force and effect). Expiration or termination of this Agreement shall not relieve the parties of
any obligation accruing prior to such expiration or termination. The rights and obligations of Twist and Customer in Sections 1.3 (pro-rated through the termination date), 1.6(b) (which will survive for the
originally agreed upon Term plus six (6) months after the Term), 1.9, and 2 through 8 (inclusive) will survive any termination of this Agreement. 

 7.5 Termination for Shortfall. Notwithstanding the foregoing, should Customer fail to place
more than [***] of the Quarterly Minimum set forth in Exhibit A for two consecutive quarters, Twist shall have the right to terminate this Agreement. 

7.6 Effects of Termination. Transactions not delivered before the effective date of expiration or termination of this Agreement shall survive
expiration or termination of this Agreement until completed, unless this Agreement is terminated for breach by a Party or insolvency of a Party. Twist shall be entitled to receive and retain all Fees due for Transactions surviving the effective date
of termination. 
 7.7 Survival. Sections 1.3, 1.6, 1.8, 1.9, 2, 3, 4, 5, 6, 7.6, 7.7 and 8 shall survive any termination or expiration of this
Agreement. Termination or expiration of this Agreement shall not affect Customer’s liability for any obligations or liabilities that have accrued prior to such expiration or termination (including without limitation any Fees owed by Customer)
or any breach of this Agreement committed before such expiration or termination. 
 8. MISCELLANEOUS 

8.1 Entire Agreement; Modification; Waiver; Counterparts. This Agreement, as of the Effective Date, together with any accepted Transactions (to
the extent provided herein), represents the entire agreement between the parties, and supersedes all prior agreements and understandings, written or oral, with respect to the matters covered herein, and is not intended to confer on any third-party
any rights or remedies hereunder. No modification of, or amendment to, nor any waiver of any rights under, this Agreement will be effective unless in a mutually signed writing. The waiver of one breach or default or any delay in exercising any
rights will not constitute a waiver of any later breach or default. This Agreement may be executed in counterparts (including by PDF or other electronic form), each of which will be deemed an original and all of which together will constitute one
instrument. 
 8.2 Delays. If either party is prevented from performing or is unable to perform any of its obligations under this Agreement
(other than any payment obligation) due to any Act of God, major forces, fire, casualty, flood, earthquake, war, strike, lockout, epidemic, destruction of production facilities, riot, insurrection, material unavailability, or any other cause beyond
the reasonable control of the party invoking this Section, and if such party will have used its commercially reasonable efforts to mitigate its effects, such party will give prompt written notice to the other party, and the time for the performance
will be extended for the period of delay or inability to perform due to such occurrences. 
 8.3 Governing Law; Arbitration; Fees. This
Agreement will in all respects be governed by the laws of the State of Delaware without reference to its principles of conflicts of laws. Any dispute or claim arising out of or in connection with this Agreement will be finally settled by binding
arbitration in Wilmington, Delaware under the Rules of Arbitration of the American Arbitration Association, by at least one arbitrator appointed in accordance with said rules. The arbitrator shall apply Delaware law, without reference to rules of
conflicts or law or rules of statutory arbitration, to the resolution of any dispute. Judgment on the award rendered by the arbitrator may be entered in any court having jurisdiction thereof. Notwithstanding the foregoing, the parties may apply to
any court of competent jurisdiction for preliminary or interim equitable relief, or to compel arbitration in accordance with this paragraph, without breach of this arbitration provision. If any action at law or in equity (including arbitration) is
necessary to enforce or interpret the terms of this Agreement, the prevailing party will be entitled to reasonable attorney’s fees, costs and necessary disbursements in addition to any other relief to which such party may be entitled. 

8.4 Relationship of the Parties. Nothing in this Agreement is to be construed as creating an agency, partnership, or joint venture relationship
between the parties hereto. Neither party will have any right or authority to assume or create any obligations or to make any representations or warranties on behalf of any other party, whether express or implied, or to bind the other party in any
respect whatsoever. Each party may identify the other as a customer or supplier, as applicable. 
 8.5 Publicity. The Parties have issued a
joint press release to announce the forthcoming execution of this Agreement, and, following the issuance of such press release, Twist and Customer may each disclose to Third Parties the information contained in such press release without the need
for further approval by the other. Neither Party shall issue any other public announcement, press release, or other public disclosure regarding this Agreement or its subject matter without the other Party’s prior written consent (which shall
not be unreasonably withheld, delayed, or conditioned). Following issuance of the press release, in the event a Party desires to issue any public announcement, press release, or other public disclosure, such Party shall submit the proposed
disclosure in writing to the other Party at least fourteen (14) Business Days prior to the anticipated date of disclosure; provided that if the 

 
other Party has not provided its consent (or indicated that it does not consent) to such proposed disclosure within such fourteen (14) day period, such consent shall be deemed to have been
given and the disclosing Party may make the proposed disclosure. With respect to such press releases, the terms of this Agreement and all activities under this Agreement will be kept confidential except as specifically agreed to by the parties or as
otherwise required by law. 
 8.6 Notices. Any notice, demand or request required or permitted to be given under this Agreement must, unless
otherwise specified in this Agreement, be in writing and will be deemed sufficient when delivered personally or by overnight courier providing evidence of receipt, addressed to the party to be notified at such party’s address as set forth on
the first page of this Agreement, as subsequently modified by written notice. Notice shall be deemed effective upon receipt. 
 8.7 Right to Notice
of Proposed Acquisitions; Discussions of Consequential Changes. Twist agrees to provide prompt written notice to Customer (an “Offer Notice”) upon Twist’s receipt of a bona fide notice, proposal, or offer, in each case in
writing, from a Specified Party in connection with a proposed merger or sale of Twist or of substantially all of the assets of Twist to which this Agreement applies (in each case a “Proposed Acquisition”) on condition that
Twist’s board of directors determines to proceed with negotiations in respect of such Proposed Acquisition. For the avoidance of doubt, (i) any Offer Notice provided pursuant to this Section 8.7 shall only be required to include an
indication that the circumstances contemplated by the first sentence of Section 8.7 have occurred and need not include any terms of such Proposed Acquisition nor the identity of the third party offeror with respect to such Proposed Acquisition
and (ii) the first sentence of Section 8.7 shall not apply to any consolidation or merger of Twist with or into any other entity in which the holders of Twist’s outstanding voting securities immediately before such consolidation or
merger, immediately after such consolidation or merger, retain voting securities representing a majority of the voting power of the surviving entity or voting securities representing a majority of the voting power of an entity that wholly owns,
directly or indirectly, the surviving entity. 
 8.8 Terminal Order. Upon receipt of a Notice of Consummated Change in Control within the last
twelve (12) months of the Term, in addition to any other rights Customer may have hereunder, Customer shall be entitled to place a single Transaction in respect to a number of Deliverables not to exceed [***] (the “Terminal
Order”) on or prior to the last day of the Term. Subject to the last sentence of this Section 8.8, Customer’s notice to Twist of its election to place a Terminal Order shall constitute a binding obligation by Customer to purchase
the quantities of Deliverables referenced therein and by Twist to supply such quantities of Deliverables. Twist shall update Customer periodically (but no less frequently than quarterly) regarding its status and progress on the Terminal Order build.
Customer, by written notice to Twist, may request to modify the specific Deliverables or quantities set forth in the Terminal Order solely to the extent that (i) Twist has not commenced the manufacture or production of such Deliverables prior
to the date Twist actually receives such notice from Customer and (ii) the number of Deliverables in the Terminal Order, as modified by such notice, does not exceed 100,000 Deliverables. 

8.9 Assignment. Neither party may assign the Agreement, in whole or in part, without the prior written consent of other party, such consent to
not be unreasonably withheld or delayed, except that either Party may make such assignment without the prior written consent of the other Party to an Affiliate, as defined below (so long as such Party shall remain jointly and severally liable with
such Affiliate with respect to all obligations so assigned and so long as such Affiliate is not a direct competitor of the other party). Subject to Customer’s right to terminate this 

Agreement in connection with a Specified Change in Control, either party may assign this Agreement without consent to the relevant acquiring entity in
connection with a merger or sale of such party or of substantially all of the assets to which this Agreement applies; [***] For purposes of this Agreement, “Affiliate” shall mean any company or entity controlled by,
controlling, or under common control with a party hereto, where “control” shall mean (i) the beneficial ownership (direct or indirect) of at least fifty percent (50%) or more of the voting stock or other ownership interest of
the subject entity entitled to vote in the election of directors (or, in the case of an entity that is not a corporation, for the election of the corresponding managing authority), or (ii) the power (direct or indirect) to direct or cause the
direction of the management and policies of the subject entity, whether through the ownership or control of voting securities, by contract or otherwise. 

[Signature Page to Follow On Next Page] 

 In witness whereof, the parties have caused this Agreement to be duly executed as of the date first
written above. 
  

									
	Twist Bioscience Corporation	 		  	Ginkgo Bioworks, Inc.
					
	By:	 	 /s/ William Banyai
	 	        	  	By:	  	 /s/ Barry Canton

	Name: William Banyai	 		  	Name: Barry Canton
	Title: Chief Operating Officer	 		  	Title: Founder

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