Document:

Exhibit 10.1

 

THE MEDICINES COMPANY

 

2004 STOCK INCENTIVE PLAN

 

1.                                      Purpose

 

The purpose of this 2004 Stock Incentive Plan (the “Plan”) of The
Medicines Company, a Delaware corporation (the “Company”), is to advance the
interests of the Company’s stockholders by enhancing the Company’s ability to
attract, retain and motivate persons who are expected to make important
contributions to the Company and by providing such persons with equity
ownership opportunities and performance-based incentives that are intended to
better align their interests with those of the Company’s stockholders. Except
where the context otherwise requires, the term “Company” shall include any of
the Company’s present or future parent or subsidiary corporations as defined in
Sections 424(e) or (f) of the Internal Revenue Code of 1986, as
amended, and any regulations promulgated thereunder (the “Code”) and any other
business venture (including, without limitation, joint venture or limited
liability company) in which the Company has a controlling interest, as
determined by the Board of Directors of the Company (the “Board”).

 

2.                                      Eligibility

 

All of the Company’s employees, officers and directors (including
persons who have entered into an agreement with the Company under which they
will be employed by the Company in the future), as well as all of the Company’s
consultants and advisors that are natural persons, are eligible to be granted
options, restricted stock awards, stock appreciation rights or other
stock-based awards (each, an “Award”) under the Plan. Each person who has been
granted an Award under the Plan shall be deemed a “Participant”.

 

3.                                      Administration
and Delegation

 

(a)          Administration
by Board of Directors.  The
Plan will be administered by the Board. The Board shall have authority to grant
Awards and to adopt, amend and repeal such administrative rules, guidelines and
practices relating to the Plan as it shall deem advisable. The Board may
correct any defect, supply any omission or reconcile any inconsistency in the
Plan or any Award in the manner and to the extent it shall deem expedient to
carry the Plan into effect and it shall be the sole and final judge of such
expediency. All decisions by the Board shall be made in the Board’s sole
discretion and shall be final and binding on all persons having or claiming any
interest in the Plan or in any Award. No director or person acting pursuant to
the authority delegated by the Board shall be liable for any action or
determination relating to or under the Plan made in good faith.

 

(b)         Appointment
of Committees.  To the extent
permitted by applicable law, the Board may delegate any or all of its powers
under the Plan to one or more committees or subcommittees of the Board (a
“Committee”). All references in the Plan to the “Board” shall mean the Board or
a Committee of the Board or the officers referred to in Section 3(c) to
the extent that the Board’s powers or authority under the Plan have been
delegated to such Committee or officers.

 

(c)          Delegation
to Officers.  To the extent
permitted by applicable law, the Board may delegate to one or more officers of
the Company the power to grant Awards to employees of the Company and to
exercise such other powers under the Plan as the Board may determine, provided
that the Board shall fix the terms of the Awards to be granted by such officers
(including the exercise price of such Awards, which may include a formula by
which the exercise price will be determined) and the maximum number of shares
subject to Awards that the officers may grant; provided further, however, that
no officer shall be authorized to grant Awards to any “executive officer” of
the Company (as defined by Rule 3b-7

 

 

under the Securities Exchange Act of 1934, as amended (the “Exchange
Act”)) or to any “officer” of the Company (as defined by Rule 16a-1 under
the Exchange Act).

 

4.                                      Stock
Available for Awards

 

(a)          Number of Shares.  Subject to adjustment under Section 9,
Awards may be made under the Plan for up to 4,400,000 shares of common stock,
$.001 par value per share, of the Company (the “Common Stock”); provided,
however, that, notwithstanding the foregoing, no more than 400,000 shares of
Common Stock may be issued pursuant to Restricted Stock Awards or Other Stock
Unit Awards (as such terms are defined below). If any Award expires or is
terminated, surrendered or canceled without having been fully exercised or is
forfeited in whole or in part (including as the result of shares of Common
Stock subject to such Award being repurchased by the Company at the original
issuance price pursuant to a contractual repurchase right) or results in any
Common Stock not being issued, the unused Common Stock covered by such Award
shall again be available for the grant of Awards under the Plan, subject,
however, in the case of Incentive Stock Options (as hereinafter defined), to
any limitations under the Code. Shares issued under the Plan may consist in
whole or in part of authorized but unissued shares or treasury shares.

 

(b)         Per-Participant
Limit.  Subject to adjustment
under Section 9, the maximum number of shares of Common Stock with respect
to which Awards may be granted to any Participant under the Plan shall be
500,000 per calendar year. The per-Participant limit described in this
Section 4(b) shall be construed and applied consistently with
Section 162(m) of the Code (“Section 162(m)”).

 

5.                                      Stock
Options

 

(a)          General.  The Board may grant options to purchase
Common Stock (each, an “Option”) and determine the number of shares of Common
Stock to be covered by each Option, the exercise price of each Option and the
conditions and limitations applicable to the exercise of each Option, including
conditions relating to applicable federal or state securities laws, as it
considers necessary or advisable. An Option which is not intended to be an Incentive
Stock Option (as hereinafter defined) shall be designated a “Nonstatutory Stock
Option”.

 

(b)         Incentive
Stock Options.  An Option
that the Board intends to be an “incentive stock option” as defined in
Section 422 of the Code (an “Incentive Stock Option”) shall only be
granted to employees of The Medicines Company, any of The Medicines Company’s
present or future parent or subsidiary corporations as defined in
Sections 424(e) or (f) of the Code, and any other entities the
employees of which are eligible to receive Incentive Stock Options under the
Code, and shall be subject to and shall be construed consistently with the
requirements of Section 422 of the Code. The Company shall have no
liability to a Participant, or any other party, if an Option (or any part
thereof) that is intended to be an Incentive Stock Option is not an Incentive
Stock Option.

 

(c)          Exercise
Price.  The Board shall
establish the exercise price at the time each Option is granted and specify it
in the applicable option agreement; provided, however, that the exercise price
shall be not less than 100% of the fair market value as determined by (or in a
manner approved by) the Board at the time the Option is granted.

 

(d)         Duration of
Options.  Each Option shall
be exercisable at such times and subject to such terms and conditions as the
Board may specify in the applicable option agreement; provided, however, that
no Option will be granted for a term in excess of 10 years.

 

(e)          Exercise
of Option.  Options may be
exercised by delivery to the Company of a written notice of exercise signed by
the proper person or by any other form of notice (including electronic notice)
approved by the Board together with payment in full as specified in
Section 5(f) for the number of shares for which the Option is exercised.

 

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(f)            Payment
Upon Exercise.  Common Stock
purchased upon the exercise of an Option granted under the Plan shall be paid
for as follows:

 

(1)          in cash or by check, payable to the order of
the Company;

 

(2)          except as the Board may otherwise provide in
an option agreement, by (i) delivery of an irrevocable and unconditional
undertaking by a creditworthy broker to deliver promptly to the Company
sufficient funds to pay the exercise price and any required tax withholding or
(ii) delivery by the Participant to the Company of a copy of irrevocable
and unconditional instructions to a creditworthy broker to promptly pay to the
Company the exercise price and any required tax withholding;

 

(3)          when the Common Stock is registered under the
Exchange Act, by delivery of shares of Common Stock owned by the Participant
valued at their fair market value as determined by (or in a manner approved by)
the Board, provided (i) such method of payment is then permitted under
applicable law, (ii) such Common Stock, if acquired directly from the
Company, was owned by the Participant at least six months prior to such
delivery and (iii) such Common Stock is not subject to any repurchase,
forfeiture, unfulfilled vesting or other similar requirements;

 

(4)          to the extent permitted by applicable law and
by the Board, by (i) delivery of a promissory note of the Participant to
the Company on terms determined by the Board, or (ii) payment of such
other lawful consideration as the Board may determine; or

 

(5)          by any combination of the above permitted
forms of payment.

 

(g)         Substitute
Options.  In connection with
a merger or consolidation of an entity with the Company or the acquisition by
the Company of property or stock of an entity, the Board may grant Options in
substitution for any options or other stock or stock-based awards granted by
such entity or an affiliate thereof prior to such merger, consolidation or
acquisition. Substitute Options may be granted on such terms as the Board deems
appropriate in the circumstances, notwithstanding any limitations on Options
contained in the other sections of this Section 5 or in Section 2.

 

(h)         No
Repricing.  Without prior
stockholder approval, the Company may not engage in any repricing with respect
to any Option or Options which requires stockholder approval under the rules of
the Nasdaq National Market or the principal market on which the Company’s
Common Stock is then traded.

 

(i)             No Reload Rights.  No Option granted under the Plan shall
contain any provision entitling the optionee to the automatic grant of
additional Options in connection with any exercise of the original Option.

 

6.                                      Stock
Appreciation Rights

 

(a)          Nature of
Stock Appreciation Rights.  A
Stock Appreciation Right is an Award entitling the holder on exercise to
receive an amount in cash or Common Stock or a combination thereof (such form
to be determined by the Board) determined in whole or in part by reference to
appreciation, from and after the date of grant, in the fair market value of a
share of Common Stock (an “SAR Award”). A Stock Appreciation Right may be based
solely on appreciation in the fair market value of Common Stock or on a
comparison of such appreciation with some other measure of market growth such
as (but not limited to) appreciation in a recognized market index. The date as
of which such appreciation or other measure is determined shall be the exercise
date unless another date is specified by the Board in the SAR Award.

 

(b)         Grants.  Stock Appreciation Rights may be granted in
tandem with, or independently of, Options granted under the Plan.

 

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(1)          Rules Applicable to
Tandem Awards.When Stock Appreciation Rights are expressly granted in tandem
with Options, the Stock Appreciation Right will be exercisable only at such
time or times, and on such conditions, as the Board may specify in the SAR
Award or the related Options.

 

(2)          Exercise of Independent
Stock Appreciation Rights.A Stock Appreciation Right not expressly granted in
tandem with an Option will become exercisable at such time or times, and on
such conditions, as the Board may specify in the SAR Award.

 

(c)          Exercise.  Any exercise of a Stock Appreciation Right
must be in writing, signed by the proper person and delivered or mailed to the
Company, accompanied by any other documents required by the Board.

 

7.                                      Restricted
Stock.

 

(a)          Grants.  The Board may grant Awards entitling
recipients to acquire shares of Common Stock, subject to the right of the
Company to repurchase all or part of such shares at their issue price or other
stated or formula price (or to require forfeiture of such shares if issued at
no cost) from the recipient in the event that conditions specified by the Board
in the applicable Award are not satisfied prior to the end of the applicable
restriction period or periods established by the Board for such Award (each, a
“Restricted Stock Award”).

 

(b)         Terms and
Conditions.  The Board shall
determine the terms and conditions of a Restricted Stock Award, including the
conditions for repurchase (or forfeiture) and the issue price, if any.

 

(c)          Limitation
on Vesting.  Restricted Stock
Awards shall not vest earlier than the first anniversary of the date of grant.
Notwithstanding any other provision of this Plan, the Board may, in its
discretion, either at the time a Restricted Stock Award is made or at any time
thereafter, waive its right to repurchase shares of Common Stock (or waive the
forfeiture thereof) or remove or modify any part or all of the restrictions
applicable to the Restricted Stock Award, provided that the Board may only
exercise such rights in extraordinary circumstances which shall include,
without limitation, death or disability of the Participant; a merger,
consolidation, sale, reorganization, recapitalization, or change in control of
the Company; or any other nonrecurring significant event affecting the Company,
a Participant or the Plan.

 

(d)         Stock
Certificates.  Any stock
certificates issued in respect of a Restricted Stock Award shall be registered
in the name of the Participant and, unless otherwise determined by the Board,
deposited by the Participant, together with a stock power endorsed in blank,
with the Company (or its designee). At the expiration of the applicable restriction
periods, the Company (or such designee) shall deliver the certificates no
longer subject to such restrictions to the Participant or if the Participant
has died, to the beneficiary designated, in a manner determined by the Board,
by a Participant to receive amounts due or exercise rights of the Participant
in the event of the Participant’s death (the “Designated Beneficiary”). In the
absence of an effective designation by a Participant, “Designated Beneficiary”
shall mean the Participant’s estate.

 

8.                                      Other
Stock-Based Awards.

 

Other Awards of shares of Common Stock, and other Awards that are
valued in whole or in part by reference to, or are otherwise based on, shares
of Common Stock or other property, may be granted hereunder to Participants
(“Other Stock Unit Awards”), including without limitation Awards entitling
recipients to receive shares of Common Stock to be delivered in the future.
Such Other Stock Unit Awards shall also be available as a form of payment in
the settlement of other Awards granted under the Plan or as payment in lieu of
compensation to which a Participant is otherwise entitled. Other Stock Unit
Awards may be paid in shares of Common Stock or cash, as the Board shall
determine.

 

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Subject to the provisions of the Plan, the Board shall determine the
conditions of each Other Stock Unit Awards, including any purchase price
applicable thereto. At the time any Award is granted, the Board may provide
that, at the time Common Stock would otherwise be delivered pursuant to the
Award, the Participant will instead receive an instrument evidencing the
Participant’s right to future delivery of the Common Stock.

 

9.                                      Adjustments
for Changes in Common Stock and Certain Other Events.

 

(a)          Changes in
Capitalization.  In the event
of any stock split, reverse stock split, stock dividend, recapitalization,
combination of shares, reclassification of shares, spin-off or other similar
change in capitalization or event, or any distribution to holders of Common Stock
other than an ordinary cash dividend, (i) the number and class of
securities available under this Plan, (ii) the limits on Awards set forth
in Section 4(a) and the per-Participant limit set forth in
Section 4(b), (iii) the number and class of securities and exercise
price per share subject to each outstanding Option, (iv) the repurchase
price per share subject to each outstanding Restricted Stock Award and
(v) the share- and per-share-related provisions of each outstanding Stock
Appreciation Right and Other Stock Unit Award shall be appropriately adjusted
by the Company (or substituted Awards may be made, if applicable) to the extent
determined by the Board.

 

(b)         Reorganization
and Change in Control Events

 

(1)          Definitions

 

(a)          A “Reorganization Event” shall mean:

 

(i)             any merger or consolidation of the Company
with or into another entity as a result of which all of the Common Stock of the
Company is converted into or exchanged for the right to receive cash,
securities or other property;

 

(ii)          any exchange of all of the Common Stock of
the Company for cash, securities or other property pursuant to a share exchange
transaction; or

 

(iii)       any liquidation or dissolution of the Company.

 

(b)         A “Change in Control Event” shall mean:

 

(i)             any sale or transfer of all or
substantially all of the assets of the Company to another corporation or
entity, any merger, consolidation or reorganization of the Company into or with
another corporation or entity, with the result that, upon conclusion of the
transaction, the voting securities of the Company immediately prior thereto do
not represent (either by remaining outstanding or by being converted into
voting securities of the surviving entity) more than 50% of the combined voting
power of the voting securities of the continuing or surviving entity of such
consolidation, merger or reorganization; or

 

(ii)          a disclosure that any person (as the term
“person” is used in Section 13(d)(3) or Section 14(d)(2) of the
Exchange Act), other than (A) the Company or (B) any corporation
owned directly or indirectly by the stockholders of the Company in
substantially the same proportion as their ownership of stock of the Company,
becomes the beneficial owner as the term “beneficial owner” is defined under
Rule 13d-3 or any successor rule or regulation thereto under the Exchange
Act) of securities representing 30% or more of the combined voting power of the
then outstanding voting securities of the Company; or

 

(iii)       such time as individuals who as of the date of
the initial adoption of this Plan constitute the Board of Directors of the
Company, and any new director (other

 

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than a director designated by a person who has entered into an
agreement with the Company to effect any transaction described in
clause (i) or (ii) of this section) whose election by the Board or
nomination for election by the Company’s stockholders was approved by a vote of
at least two-thirds of the directors then still in office who were either
directors at the beginning of the period or whose election or whose nomination
for election was previously so approved, cease for any reason to constitute a
majority of the Board of Directors; or

 

(iv)      the liquidation or dissolution of the Company.

 

(c)          “Cause” shall mean
(i) conviction of any felony or any crime involving moral turpitude or
dishonesty; (ii) participation in a fraud or act of dishonesty against the
Company (or, if applicable, a successor corporation to the Company);
(iii) willful and material breach of the Company’s policies (or, if
applicable, a successor corporation to the Company); (iv) intentional and
material damage to the Company’s property (or, if applicable, a successor
corporation to the Company); or (v) material breach of the Participant’s
confidentiality obligations or duties under the Participant’s non-disclosure,
non-competition or other similar agreement with the Company (or, if applicable,
a successor corporation to the Company).

 

(d)         “Termination Event” shall
mean the termination of the Participant’s employment (i) by the Company or
the acquiring or succeeding corporation without Cause; (ii) as a result of
Participant’s death or disability (within the meaning of Section 22(4)(3)
of the Code); or (iii) by the Participant upon written notice given promptly
after the Company’s or the acquiring or succeeding corporation’s taking of any
of the following actions, which actions shall not have been cured within a
30-day period following such notice: (A) the principal place of the
performance of the Participant’s responsibilities (the “Principal Location”) is
changed to a location outside of a 30 mile radius from the Principal Location
immediately prior to the Reorganization Event; (B) there is a material
reduction in the Participant’s responsibilities without Cause; (C) there
is a material reduction in the Participant’s salary; or (D) there is a
significant diminution in the scope of the Participant’s responsibilities
without the Participant’s agreement (excluding increases in responsibility and
sideways moves to jobs with similar descriptions).

 

(2)          Effect
on Options

 

(a)          Reorganization Event.  Upon the occurrence of a Reorganization
Event (regardless of whether such event also constitutes a Change in Control
Event), or the execution by the Company of any agreement with respect to a
Reorganization Event (regardless of whether such event will result in a Change
in Control Event), the Board shall provide that all outstanding Options shall
be assumed, or equivalent options shall be substituted, by the acquiring or succeeding
corporation (or an affiliate thereof); provided that if such Reorganization
Event also constitutes a Change in Control Event, except to the extent
specifically provided to the contrary in the instrument evidencing any Option
or any other agreement between a Participant and the Company, such assumed or
substituted options shall become immediately exercisable in full if, on or
prior to the first anniversary of the date of the consummation of the Change in
Control Event, a Termination Event occurs. For purposes hereof, an Option shall
be considered to be assumed if, following consummation of the Reorganization
Event, the Option confers the right to purchase, for each share of Common Stock
subject to the Option immediately prior to the consummation of the
Reorganization Event, the consideration (whether cash, securities or other
property) received as a result of the Reorganization Event by holders of Common
Stock for each share of Common Stock held immediately prior to the consummation
of the Reorganization Event (and if holders were

 

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offered a choice of consideration, the type
of consideration chosen by the holders of a majority of the outstanding shares
of Common Stock); provided, however, that if the consideration received as a
result of the Reorganization Event includes but does not solely consist of
common stock of the acquiring or succeeding corporation (or an affiliate
thereof), the Company may, with the consent of the acquiring or succeeding corporation,
provide for the consideration to be received upon the exercise of Options to
consist solely of common stock of the acquiring or succeeding corporation (or
an affiliate thereof) equivalent in fair market value to the per share
consideration received by holders of outstanding shares of Common Stock as a
result of the Reorganization Event.

 

Notwithstanding
the foregoing, (i) if the acquiring or succeeding corporation (or an
affiliate thereof) does not agree to assume, or substitute for, such Options, or
in the event of a liquidation or dissolution of the Company, the Board shall,
upon written notice to the Participants,
provide that all then unexercised Options will become exercisable in full as of
a specified time prior to the Reorganization Event and will terminate
immediately prior to the consummation of such Reorganization Event, except to
the extent exercised by the Participants before the consummation of such
Reorganization Event, and (ii) in the event of a Reorganization Event
under the terms of which holders of Common Stock will receive upon consummation
thereof a cash payment for each share of Common Stock surrendered pursuant to
such Reorganization Event (the “Acquisition Price”), the Board shall either
(A) upon written notice to the Participants, provide that all then
unexercised Options will become exercisable in full as of a specified time
prior to the Reorganization Event and will terminate immediately prior to the
consummation of such Reorganization Event, except to the extent exercised by the
Participants before the consummation of such Reorganization Event or
(B) provide that all outstanding Options shall terminate upon consummation
of such Reorganization Event and that each Participant shall receive, in
exchange therefor, a cash payment equal to the amount (if any) by which
(x) the Acquisition Price multiplied by the number of shares of Common
Stock subject to such outstanding Options (whether or not then exercisable),
exceeds (y) the aggregate exercise price of such Options.

 

(b)         Change in Control Event
that is not a Reorganization Event.  Upon
the occurrence of a Change in Control Event that does not also constitute a
Reorganization Event, except to the extent specifically provided to the
contrary in the instrument evidencing any Option or any other agreement between
a Participant and the Company, each such Option shall become immediately
exercisable in full if, on or prior to the first anniversary of the date of the
consummation of the Change in Control Event, a Termination Event occurs.

 

(3)          Effect on Restricted
Stock Awards

 

(a)          Reorganization Event
that is not a Change in Control Event. 
Upon the occurrence of a Reorganization Event that is not a Change in
Control Event, the repurchase and other rights of the Company under each
outstanding Restricted Stock Award shall inure to the benefit of the Company’s
successor and shall apply to the cash, securities or other property which the
Common Stock was converted into or exchanged for pursuant to such
Reorganization Event in the same manner and to the same extent as they applied
to the Common Stock subject to such Restricted Stock Award.

 

(b)         Change in Control Event.  Upon the occurrence of a Change in Control
Event (regardless of whether such event also constitutes a Reorganization
Event), except to the extent specifically provided to the contrary in the
instrument evidencing any Restricted Stock Award or any other agreement between
a Participant and the Company, each such Restricted Stock Award shall
immediately become free from all conditions or restrictions if, on or prior to
the first anniversary of the date of the consummation of the Change in Control
Event, a Termination Event occurs.

 

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(4)          Effect on Stock
Appreciation Rights and Other Stock Unit Awards

 

The Board may specify in an Award at the time
of the grant the effect of a Reorganization Event and Change in Control Event
on any SAR and Other Stock Unit Award.

 

10.                               General
Provisions Applicable to Awards

 

(a)          Transferability
of Awards.  Except as the
Board may otherwise determine or provide in an Award, Awards shall not be sold,
assigned, transferred, pledged or otherwise encumbered by the person to whom
they are granted, either voluntarily or by operation of law, except by will or
the laws of descent and distribution or, other than in the case of an Option
intended to be an Incentive Stock Option, pursuant to a qualified domestic
relations order, and, during the life of the Participant, shall be exercisable
only by the Participant. References to a Participant, to the extent relevant in
the context, shall include references to authorized transferees.
Notwithstanding the foregoing, a Participant may transfer any Award by means of
a gift to a family member (as such term is defined in General Instruction A to
Form S-8, as may be amended from time to time) of such Participant,
provided that prior written notice of such gift is provided to the Company.

 

(b)         Documentation.  Each Award shall be evidenced in such form
(written, electronic or otherwise) as the Board shall determine. Each Award may
contain terms and conditions in addition to those set forth in the Plan.

 

(c)          Board
Discretion.  Except as
otherwise provided by the Plan, each Award may be made alone or in addition or
in relation to any other Award. The terms of each Award need not be identical,
and the Board need not treat Participants uniformly.

 

(d)         Termination
of Status.  The Board shall
determine the effect on an Award of the disability, death, retirement,
authorized leave of absence or other change in the employment or other status
of a Participant and the extent to which, and the period during which, the
Participant, or the Participant’s legal representative, conservator, guardian
or Designated Beneficiary, may exercise rights under the Award.

 

(e)          Withholding.   Each Participant shall pay to the Company,
or make provision satisfactory to the Company for payment of, any taxes
required by law to be withheld in connection with Awards to such Participant
pursuant to such rules and procedures as the Company may adopt. Except as the
Board may otherwise provide in an Award, when the Common Stock is registered
under the Exchange Act, Participants may satisfy such tax obligations in whole
or in part by delivery of shares of Common Stock, including shares retained
from the Award creating the tax obligation, valued at their fair market value
as determined by (or in a manner approved by) the Board; provided, however,
that the total tax withholding where stock is being used to satisfy such tax obligations
cannot exceed the Company’s minimum statutory withholding obligations (based on
minimum statutory withholding rates for federal and state tax purposes,
including payroll taxes, that are applicable to such supplemental taxable
income). Shares surrendered to satisfy tax withholding requirements cannot be
subject to any repurchase, forfeiture, unfulfilled vesting or other similar
requirements. The Company may, to the extent permitted by law, deduct any such
tax obligations from any payment of any kind otherwise due to a Participant.

 

(f)            Amendment
of Award.  Except as
prohibited by Section 5(h), the Board may amend, modify or terminate any
outstanding Award, including but not limited to, substituting therefor another
Award of the same or a different type, changing the date of exercise or
realization, and converting an Incentive Stock Option to a Nonstatutory Stock
Option, provided that the Participant’s consent to such action shall be
required unless the Board determines that the action, taking into account any
related action, would not materially and adversely affect the Participant.

 

(g)         Conditions
on Delivery of Stock.  The
Company will not be obligated to deliver any shares of Common Stock pursuant to
the Plan or to remove restrictions from shares previously delivered under

 

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the Plan until (i) all conditions of the Award have been met or
removed to the satisfaction of the Company, (ii) in the opinion of the
Company’s counsel, all other legal matters in connection with the issuance and
delivery of such shares have been satisfied, including any applicable
securities laws and any applicable stock exchange or stock market rules and
regulations, and (iii) the Participant has executed and delivered to the Company
such representations or agreements as the Company may consider appropriate to
satisfy the requirements of any applicable laws, rules or regulations.

 

(h)         Acceleration.  The Board may at any time provide that any
Award shall become immediately exercisable in full or in part, free of some or
all restrictions or conditions, or otherwise realizable in full or in part, as
the case may be.

 

(i)             Deferrals.  The Board may permit Participants to defer
receipt of any Common Stock issuable upon exercise of an Option or upon the
lapse of any restriction applicable to any Restricted Stock Award, subject to
such rules and procedures as it may establish.

 

11.                               Miscellaneous

 

(a)          No Right To Employment
or Other Status.  No person shall
have any claim or right to be granted an Award, and the grant of an Award shall
not be construed as giving a Participant the right to continued employment or
any other relationship with the Company. The Company expressly reserves the
right at any time to dismiss or otherwise terminate its relationship with a
Participant free from any liability or claim under the Plan, except as
expressly provided in the applicable Award.

 

(b)         No Rights As Stockholder.  Subject to the provisions of the applicable
Award, no Participant or Designated Beneficiary shall have any rights as a
stockholder with respect to any shares of Common Stock to be distributed with
respect to an Award until becoming the record holder of such shares.
Notwithstanding the foregoing, in the event the Company effects a split of the
Common Stock by means of a stock dividend and the exercise price of and the
number of shares subject to such Option are adjusted as of the date of the
distribution of the dividend (rather than as of the record date for such
dividend), then an optionee who exercises an Option between the record date and
the distribution date for such stock dividend shall be entitled to receive, on
the distribution date, the stock dividend with respect to the shares of Common
Stock acquired upon such Option exercise, notwithstanding the fact that such
shares were not outstanding as of the close of business on the record date for
such stock dividend.

 

(c)          Effective Date and Term
of Plan.  The Plan shall become
effective on the date on which it is adopted by the Board, but no Award may be
granted unless and until the Plan has been approved by the Company’s
stockholders. No Awards shall be granted under the Plan after the date
10 years from the date on which the Plan was adopted by the Board,
provided that Awards granted prior to that date may extend beyond such date.

 

(d)         Amendment of Plan.  The Board may amend, suspend or terminate
the Plan or any portion thereof at any time; provided that, to the extent
determined by the Board, no amendment requiring stockholder approval under any
applicable legal, regulatory or listing requirement shall become effective
until such stockholder approval is obtained. No Award shall be made that is
conditioned upon stockholder approval of any amendment to the Plan.

 

(e)          Provisions for Foreign
Participants.  The Board may,
without amending the Plan, modify Awards or Options granted to Participants who
are foreign nationals or employed outside the United States or establish
subplans under the Plan to recognize differences in laws, rules, regulations or
customs of such foreign jurisdictions with respect to tax, securities,
currency, employee benefit or other matters.

 

(f)            Governing Law.  The provisions of the Plan and all Awards
made hereunder shall be governed by and interpreted in accordance with the laws
of the State of Delaware, without regard to any applicable conflicts of law.

 

9Exhibit
10.2

 

THE MEDICINES COMPANY

 

Nonstatutory Stock
Option Agreement

Under 2004 Stock Incentive Plan

 

1.                                       Grant
of Option.

 

(a)                                  This
agreement evidences the grant by The Medicines Company, a Delaware corporation
(the “Company”), on         , 2004
(the “Grant Date”) to
                           ,
an [employee], [consultant] of the Company (the “Participant”), of an option to
purchase, in whole or in part, on the terms provided herein and in the
Company’s 2004 Stock Incentive Plan (the “Plan”),  a total of                    shares
(the “Shares”) of common stock, $0.001 par value per share (“Common Stock”), of
the Company at a price of $              per
Share.  Unless earlier terminated, this
option shall expire on the tenth anniversary of the Grant Date (the “Final
Exercise Date”).  

 

(b)                                 It
is intended that the option evidenced by this agreement shall not be an
incentive stock option as defined in Section 422 of the Internal Revenue
Code of 1986, as amended and any regulations promulgated thereunder (the
“Code”).  Except as otherwise indicated
by the context, the term “Participant”, as used in this option, shall be deemed
to include any person who acquires the right to exercise this option validly
under its terms.

 

2.                                       Vesting
Schedule.

 

(a)                                  This
option will become exercisable (“vest”) in equal monthly installments in
arrears over the four-year period commencing on the Grant Date.  This option shall expire upon, and will not
be exercisable after, the Final Exercise Date.

 

(b)                                 The
right of exercise shall be cumulative so that to the extent the option is not
exercised in any period to the maximum extent permissible it shall continue to
be exercisable, in whole or in part, with respect to all Shares for which it is
vested until the earlier of the Final Exercise Date or the termination of this
option under Section 3 hereof or the Plan. 

 

(c)                                  Notwithstanding anything in this option
to the contrary, in the event that the Participant’s relationship with the
Company is terminated by reason of death or disability (within the meaning of
Section 22(e)(3) of the Code), then, in addition to the Shares as to which
this option is exercisable as of such termination date pursuant to the terms
hereof, this option shall also become exercisable for an additional number of Shares
equal to 50% of the Shares covered by this option which were not otherwise

 

 

exercisable as of such
termination date.  For example, if as of
the termination date, 6,000 shares of a 10,000 share stock option had vested
and no shares covered by such option had been exercised, upon such termination
date, the option would become exercisable for an additional 2,000 shares (50%
of (10,000 - 6,000)) or total of 8,000 shares. 

 

3.                                       Exercise
of Option.

 

(a)                                  Form
of Exercise.  Each election to
exercise this option shall be in writing, signed by the Participant, and
received by the Company at its principal office, accompanied by this agreement,
and payment in full in the manner provided in the Plan.  The Participant may purchase less than the
number of Shares covered hereby, provided that no partial exercise of this
option may be for any fractional share or for fewer than ten whole shares.

 

(b)                                 Continuous
Relationship with the Company Required. 
Except as otherwise provided in this Section 3, this option may not
be exercised unless the Participant, at the time he or she exercises this
option, is, and has been at all times since the date of grant of this option,
an employee, officer or director of, or consultant or advisor to, the Company
or any parent or subsidiary of the Company as defined in Section 424(e) or
(f) of the Code (an “Eligible Participant”).

 

(c)                                  Termination
of Relationship with the Company. 
If the Participant ceases to be an Eligible Participant for any reason,
then, except as provided in paragraphs (d) and (e) below, the right to exercise
this option shall terminate three months after such cessation (but in no event
after the Final Exercise Date), provided  that this option shall
be exercisable only to the extent that the Participant was entitled to exercise
this option on the date of such cessation. 
Notwithstanding the foregoing, if the Participant, prior to the Final
Exercise Date, violates the non-competition or confidentiality provisions of
any employment contract, confidentiality and nondisclosure agreement or other
agreement between the Participant and the Company, the right to exercise this
option shall terminate immediately upon written notice to the Participant from
the Company describing such violation.

 

(d)                                 Exercise
Period Upon Death or Disability.  If
the Participant dies or becomes disabled (within the meaning of
Section 22(e)(3) of the Code) prior to the Final Exercise Date while he or
she is an Eligible Participant and the Company has not terminated such
relationship for “cause” as specified in paragraph (e) below, this option shall
be exercisable for a period of one year following the date of death or
disability of the Participant, provided  that this option shall be
exercisable only to the extent that this option was exercisable by the Participant
on the date of his or her death or disability, and further provided that this
option shall not be exercisable after the Final Exercise Date.

 

2

 

(e)                                  Discharge
for Cause.  If the Participant,
prior to the Final Exercise Date, is discharged by the Company for Cause, the
right to exercise this option shall terminate immediately upon the effective
date of such discharge.  “Cause” shall
mean:  (i) conviction of any felony or
any crime involving moral turpitude or dishonesty; (ii) participation in a
fraud or act of dishonesty against the Company (or, if applicable, a successor
corporation to the Company); (iii) willful and material breach of the Company’s
policies (or, if applicable, the policies of a successor corporation to the
Company); (iv) intentional and material damage to the Company’s property (or,
if applicable, the property of a successor corporation to the Company); or (v)
material breach of such Participant’s non-disclosure, non-competition or other
similar agreement with the Company (or, if applicable, a successor corporation
to the Company). 

 

4.                                       Withholding.

 

No Shares will be issued
pursuant to the exercise of this option unless and until the Participant pays
to the Company, or makes provision satisfactory to the Company for payment of,
any federal, state or local withholding taxes required by law to be withheld in
respect of this option.

 

5.                                       Non-transferability
of Option.

 

This option may not be
sold, assigned, transferred, pledged or otherwise encumbered by the
Participant, either voluntarily or by operation of law, except by will or the
laws of descent and distribution and, during the lifetime of the Participant,
this option shall be exercisable only by the Participant.  Notwithstanding the foregoing, a Participant
may transfer this option by means of a gift to a family member (as such term is
defined in General Instruction A to Form S-8, as may be amended from time to
time) of such Participant, provided that prior written notice of such gift is
provided to the Company.

 

6.                                       Provisions
of the Plan.

 

This option is subject to
the provisions of the Plan, a copy of which is furnished to the Participant
with this option.  

 

3

 

IN WITNESS WHEREOF, the
Company has caused this option to be executed under its corporate seal by its
duly authorized officer.  This option
shall take effect as a sealed instrument. 

 

	
   

  	
  The Medicines Company

  
	
   

  	
   

  
	
  Dated: 

  	
   

  	
   

  	
  By:

  	
   

  	
   

  
	
   

  	
  Name:

  	
  Steven Koehler

  
	
   

  	
  Title:

  	
  CFO

  
							

 

 

PARTICIPANT’S
ACCEPTANCE

 

The undersigned hereby
accepts the foregoing option and agrees to the terms and conditions
thereof.  The undersigned hereby
acknowledges receipt of a copy of the Company’s 2004 Stock Incentive Plan
Prospectus.

 

	
   

  	
  PARTICIPANT:

  
	
   

  	
   

  
	
   

  	
   

  
	
   

  	
   

  	
   

  
	
   

  	
  [Name]

  	
   

  
	
   

  	
  Date:

  	
   

  	
   

  
	
   

  	
   

  	
   

  	
   

  
	
   

  	
  Address:

  	
   

  	
   

  
	
   

  	
   

  	
   

  	
   

  
	
   

  	
   

  	
   

  	
   

  
					

 

4

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