Document:

Engagement Letter

 Exhibit 10.16 
 Synthetic Blood International, Inc. 
 3189 Airway Avenue, Building C 
 Costa Mesa, CA 92626 
 To: 
 Mr. Christian J. Stern 
 9431 Oglebay Court 
 Raleigh, N.C. 27617 
 Engagement Letter 
 Dear Chris: 
 Subject to our by-laws we herewith confirm your engagement as
a director and chairman of the board of our company (SYBD). 
 We agreed that monetary compensation shall be through a consulting contract with IFEM
Management Consultants, Inc. 
 Independent of the aforementioned consulting contract, we will pay you the following stock compensation for your services:

 Stock options (3 years life), exercisable at a price of $0.245, as follows: 
 1,000,000 with this appointment to the board of directors; 
 4,000,000 at closing of a license agreement, or sale of the
company within 24 months after appointment to the board of directors. 
 With regard to the services to be performed by you pursuant to the terms of this
engagement, you shall not be liable to SYBD, or to anyone who may claim any right due to any relationship with SYBD, for any acts or omissions in the performance of services on your part. SYBD shall hold your free and harmless from any obligations,
costs, claims, judgments, attorneys’ fees, and attachments arising from or growing out of the services rendered to SYBD pursuant to the terms of this agreement or in any way connected with the rendering of services, except when you are adjudged
to be guilty of willful misconduct or gross negligence by a court of competent jurisdiction. SYBD shall maintain an appropriate director’s and officer’s (D&O) insurance at all times and cover you under such a policy. 
  

			
	 Sincerely,
 Synthetic Blood International, Inc. (SYBD)

  
 /s/                                       
                         11/19/07
  
 By:                                       
                       Date:
	 	 Accepted:
  
 /s/                                       
                                     11/19/07
  
 Christian (a.K.a. Chris) J. Stern
                            Date:

 Synthetic Blood International, Inc. 
 3189 Airway Avenue, Building C 
 Costa Mesa, CA 92626 
 To: 
 Mr. Christian J. Stern 
 9431 Oglebay Court 
 Raleigh, N.C. 27617 
 Amendment of Engagement Letter 
 Dear Chris: 
 On March 25, 2008 the board of directors of Synthetic Blood International, Inc. decided to amend your engagement as follows: 
 Additional to your unchanged role as director and chairman of the board of our company (SYBD), we have elected you to be Chief Executive Officer. 
 We agreed that additional monetary compensation shall be through an amendment of your consulting contract with IFEM Management Consultants, Inc. 
 Independent of the aforementioned consulting contract, we will pay you the following additional stock compensation for your services: 
 14,000 restricted shares per month, issuable every 1st
 of the month, beginning April 1, 2008. 
 Additional benefit to serve on the Executive Committee: An
additional (to any other already existing) severance package of $200,000 in cash and 100,000 shares of SYBD, payable at date/the day of termination, should the company terminate you as a board member for whatever reason, cause or no cause.

 All other clauses unchanged. 
  

			
	 Sincerely,
 Synthetic Blood International, Inc. (SYBD)

  
 /s/                                       
                       03/26/08
  
 By:    Richard M.
Kiral                            Date:
	 	 Accepted:
  
  
 /s/                                       
                                     03/26/08
  
 Christian (a.K.a. Chris) J.
Stern                            Date:Business Consultant Agreement

 Exhibit 10.17 
 BUSINESS CONSULTANT AGREEMENT 
 This agreement dated November 19, 2007, is made By and Between Synthetic Blood,
International, Inc., whose address is 3189 Airway Avenue, Building C, Costa Mesa, CA 92626, (“Company”), AND IFEM Management Consultants, Inc., whose address is 9431 Oglebay Court, Raleigh, NC 27617, (“Consultant.”) 

1. Consultation Services. The company hereby employs the consultant to perform the following services in accordance with the terms and conditions set forth in this
agreement: The consultant will consult with the officers and employees of the company concerning matters relating to the management and organization of the company, their financial policies, the terms and conditions of employment, and generally any
matter arising out of the business affairs of the company. 
 2. Terms of Agreement. This agreement will begin November 19, 2007. Either party may
cancel this agreement on ninety (90) days notice to the other party in writing, by certified mail or personal delivery. 
 3. Time Devoted by
Consultant. It is anticipated the consultant will assign Dr. Chris J. Stern to this account and that he will spend approximately five days per month in fulfilling its obligations under this contract. The particular amount of time may vary
from day to day or week to week. However, the consultant shall devote sufficient time to its duties in accordance with this agreement. 
 4. Place Where
Services Will Be Rendered. The consultant will perform most services in accordance with this contract at a location of consultant’s discretion. In addition the consultant will perform services on the telephone and at such other places as
necessary to perform these services in accordance with this agreement. 
 5. Payment to Consultant.
The consultant will be paid at the rate of $15,000 per month for work performed in accordance with this agreement. Payment will be by electronic transfer on, or before the 20th day of each month, as long as the agreement is in force. Consultant is entitled to reimbursement of reasonable expenses for travel. The company will reimburse the consultant expenses as indicated by statements
submitted by the consultant within ten (10) days of receipt. 
 6. Independent Contractor. Both the company and the consultant agree that the consultant
will act as an independent contractor in the performance of its duties under this contract. Accordingly, the consultant shall be responsible for payment of all taxes including Federal, State and local taxes arising out of the consultant’s
activities in accordance with this contract, including by way of illustration but not limitation, Federal and State income tax, Social Security tax, Unemployment Insurance taxes, and any other taxes or business license fee as required. 

7. Confidential Information. The consultant agrees that any information received by the consultant during any furtherance of the consultant’s obligations in
accordance with this contract, which concerns the personal, financial or other affairs of the company will be treated by the consultant in full confidence and will not be revealed to any other persons, firms or organizations. 
  

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 8. Employment of Others. The company may from time to time request that the consultant arrange for the services of
others. All costs to the consultant for those services will be paid by the company but in no event shall the consultant employ others without the prior authorization of the company. 
 9. Liability. With regard to the services to be performed by the Consultant pursuant to the terms of this agreement, the Consultant shall not be liable to the Company, or to anyone who may claim any right due to any
relationship with the Corporation, for any acts or omissions in the performance of services on the part of the Consultant or on the part of the agents or employees of the Consultant. The Company shall hold the Consultant free and harmless from any
obligations, costs, claims, judgments, attorneys’ fees, and attachments arising from or growing out of the services rendered to the Company pursuant to the terms of this agreement or in any way connected with the rendering of services, except
when the Consultant is adjudged to be guilty of willful misconduct or gross negligence by a court of competent jurisdiction. 
 10. Arbitration. Any
controversy or claim arising out of or relating to this contract, or the breach thereof, shall be settled by arbitration in accordance of the rules of the American Arbitration Association, and judgment upon the award rendered by the arbitrator(s)
shall be entered in any court having jurisdiction thereof. For that purpose, the parties hereto consent to the jurisdiction and venue of an appropriate court located in Wake County, State of North Carolina. In the event that litigation results from
or arises out of this Agreement or the performance thereof, the parties agree to reimburse the prevailing party’s reasonable attorney’s fees, court costs, and all other expenses, whether or not taxable by the court as costs, in addition to
any other relief to which the prevailing party may be entitled. In such event, no action shall be entertained by said court or any court of competent jurisdiction if filed more than one year subsequent to the date the cause(s) of action actually
accrued regardless of whether damages were otherwise as of said time calculable. 
  

			
	By: Company	 	By: Consultant
		
	/s/	 	/s/
		
	Synthetic Blood International, Inc.	 	Institute for Efficient Management, Inc.
	By: Robert Larsen, President	 	By: Chris J. Stern, President

  

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 AMENDMENT #1 OF BUSINESS CONSULTANT AGREEMENT 
 This is an amendment #1 dated March 25, 2008 to the agreement dated November 19, 2007, made By and Between Synthetic Blood, International, Inc., whose address
is 3189 Airway Avenue, Building C, Costa Mesa, CA 92626, (“Company”), AND IFEM Management Consultants, Inc., whose address is 9431 Oglebay Court, Raleigh, NC 27617, (“Consultant.”) 
 5. Payment to Consultant. The pay to the consultant will be increased at the rate of $5,000 per month for work performed in accordance with this agreement. The
consultant will also be paid $2,500 per month for additional secretarial and administration expenses. 
 All other clauses unchanged. 
 March 25, 2008 
  

			
	By: Company	 	By: Consultant
		
	/s/	 	/s/
		
	Synthetic Blood International, Inc.	 	Institute for Efficient Management, Inc.
	By: Richard M. Kiral	 	By: Chris J. Stern

  

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