Document:

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                                                                    Exhibit 10.3

                            COR THERAPEUTICS, INC.
                       1991 EMPLOYEE STOCK PURCHASE PLAN

                            (Adopted May 14, 1991)
                                (Amended 1992)
                                (Amended 1993)
                           (Amended January 6, 1995)
                          (Amended November 15, 1996)
                          (Amended January 24, 1997)
                          (Amended November 20, 1998)
              (Adjusted for 2-for-1 Stock Split August 15, 2000)
                          (Amended February 14, 2001)

                            Termination Date: None

1.       Purpose.

         (a) The purpose of the 1991 Employee Stock Purchase Plan ("the Plan")
is to provide a means by which employees of COR Therapeutics, Inc., a Delaware
corporation (the "Company"), and its Affiliates, as defined in subparagraph
1(b), which are designated as provided in subparagraph 2(b), may be given an
opportunity to purchase stock of the Company.

         (b) The word "Affiliate" as used in the Plan means any parent
corporation or subsidiary corporation of the Company, as those terms are defined
in Sections 424(e) and (f), respectively, of the Internal Revenue Code of 1986,
as amended (the "Code").

         (c) The Company, by means of the Plan, seeks to retain the services of
its employees, to secure and retain the services of new employees, and to
provide incentives for such persons to exert maximum efforts for the success of
the Company.

         (d) The Company intends that the rights to purchase stock of the
Company granted under the Plan be considered options issued under an "employee
stock purchase plan" as that term is defined in Section 423(b) of the Code.

2.       Administration.

         (a) The Plan shall be administered by the Board of Directors (the
"Board") of the Company unless and until the Board delegates administration to a
Committee, as provided in subparagraph 2(c). Whether or not the Board has
delegated administration, the Board shall have the final power to determine all
questions of policy and expediency that may arise in the administration of the
Plan.

         (b) The Board shall have the power, subject to, and within the
limitations of, the express provisions of the Plan:
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             (i)    To determine when and how rights to purchase stock of the
Company shall be granted and the provisions of each offering of such rights
(which need not be identical).

             (ii)   To designate from time to time which Affiliates of the
Company shall be eligible to participate in the Plan.

             (iii)  To construe and interpret the Plan and rights granted under
it, and to establish, amend and revoke rules and regulations for its
administration. The Board, in the exercise of this power, may correct any
defect, omission or inconsistency in the Plan, in a manner and to the extent it
shall deem necessary or expedient to make the Plan fully effective.

             (iv)   To amend the Plan as provided in paragraph 13.

             (v)    Generally, to exercise such powers and to perform such acts
as the Board deems necessary or expedient to promote the best interests of the
Company.

         (c) The Board may delegate administration of the Plan to a Committee
composed of one (1) or more members of the Board (the "Committee"). If
administration is delegated to a Committee, the Committee shall have, in
connection with the administration of the Plan, the powers theretofore possessed
by the Board, subject, however, to such resolutions, not inconsistent with the
provisions of the Plan, as may be adopted from time to time by the Board. The
Board may abolish the Committee at any time and revest in the Board the
administration of the Plan.

3.       Shares Subject to the Plan.

         Subject to the provisions of paragraph 12 relating to adjustments upon
changes in stock, the stock that may be sold pursuant to rights granted under
the Plan shall not exceed in the aggregate two million five hundred fifty
thousand (2,550,000) shares/1/ of the Company's $0.0001 par value common stock
(the "Common Stock"). If any right under the Plan shall for any reason terminate
without having been exercised, the Common Stock not purchased under such right
shall again become available for the Plan.

4.       Grant of Rights; Offering.

         The Board or the Committee may from time to time grant or provide for
the grant of rights to purchase Common Stock of the Company under the Plan to
eligible employees (an "Offering") on a date or dates (the "Offering Date(s)")
selected by the Board or the Committee. Each Offering shall be in such form and
shall contain such terms and conditions as the Board or the Committee shall deem
appropriate. If an employee has more than one right outstanding under the Plan,
unless he or she otherwise indicates in agreements or notices delivered
hereunder (a) each agreement or notice delivered by that employee will be deemed
to apply to all of his or her rights under the Plan, and (b) a right with a
lower exercise price (or an earlier-granted right,

_________________
/1/ Pursuant to paragraph 12(a), the aggregate of 1,050,000 shares of Common
Stock in the share reserve was adjusted to an aggregate of 2,100,000 shares of
Common Stock to reflect the 2-for-1 stock split on August 15, 2000. On February
14, 2001 the Board of Directors increased this number by 450,000 shares, to a
total aggregate of 2,550,000 shares of Common Stock.

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if two rights have identical exercise prices), will be exercised to the fullest
possible extent before a right with a higher exercise price (or a later-granted
right, if two rights have identical exercise prices) will be exercised. The
provisions of separate Offerings need not be identical, but each Offering shall
include (through incorporation of the provisions of this Plan by reference in
the Offering or otherwise) the substance of the provisions contained in
paragraphs 5 through 8, inclusive.

5.       Eligibility.

         (a) Rights may be granted only to employees of the Company or, as the
Board or the Committee may designate as provided in subparagraph 2(b), to
employees of any Affiliate of the Company. Except as provided in subparagraph
5(b), an employee of the Company or any Affiliate shall not be eligible to be
granted rights under the Plan, unless, on the Offering Date, such employee has
been in the employ of the Company or any Affiliate for such continuous period
preceding such grant as the Board or the Committee may require, but in no event
shall the required period of continuous employment be equal to or greater than
two (2) years. In addition, unless otherwise determined by the Board or the
Committee and set forth in the terms of the applicable Offering, no employee of
the Company or any Affiliate shall be eligible to be granted rights under the
Plan, unless, on the Offering Date, such employee's customary employment with
the Company or such Affiliate is at least twenty (20) hours per week and at
least five (5) months per calendar year.

         (b) The Board or the Committee may provide that each person who, during
the course of an Offering, first becomes an eligible employee of the Company or
designated Affiliate will, on a date or dates specified in the Offering which
coincides with the day on which such person becomes an eligible employee or
occurs thereafter, receive a right under that Offering, which right shall
thereafter be deemed to be a part of that Offering. Such right shall have the
same characteristics as any rights originally granted under that Offering, as
described herein, except that:

             (i)    the date on which such right is granted shall be the
"Offering Date" of such right for all purposes, including determination of the
exercise price of such right;

             (ii)   the Purchase Period (as defined below) for such right shall
begin on its Offering Date and end coincident with the end of such Offering; and

             (iii)  the Board or the Committee may provide that if such person
first becomes an eligible employee within a specified period of time before the
end of the Purchase Period (as defined below) for such Offering, he or she will
not receive any right under that Offering.

         (c) No employee shall be eligible for the grant of any rights under the
Plan if, immediately after any such rights are granted, such employee owns stock
possessing five percent (5%) or more of the total combined voting power or value
of all classes of stock of the Company or of any Affiliate. For purposes of this
subparagraph 5(c), the rules of Section 424(d) of the Code shall apply in
determining the stock ownership of any employee, and stock which such employee
may purchase under all outstanding rights and options shall be treated as stock
owned by such employee.

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         (d) An eligible employee may be granted rights under the Plan only if
such rights, together with any other rights granted under "employee stock
purchase plans" of the Company and any Affiliates, as specified by Section
423(b)(8) of the Code, do not permit such employee's rights to purchase stock of
the Company or any Affiliate to accrue at a rate which exceeds twenty-five
thousand dollars ($25,000) of fair market value of such stock (determined at the
time such rights are granted) for each calendar year in which such rights are
outstanding at any time.

6.       Rights; Purchase Price.

         (a) On each Offering Date, each eligible employee, pursuant to an
Offering made under the Plan, shall be granted the right to purchase the number
of shares of Common Stock of the Company purchasable with up to fifteen percent
(15%) (or such lower percentage as the Board determines for a particular
Offering) of such employee's Earnings (as defined in paragraph 7(a)) during the
period which begins on the Offering Date (or such later date as the Board
determines for a particular Offering) and ends on the date stated in the
Offering, which date shall be no more than twenty-seven (27) months after the
Offering Date (the "Purchase Period"). In connection with each Offering made
under this Plan, the Board or the Committee shall specify a maximum number of
shares which may be purchased by any employee as well as a maximum aggregate
number of shares which may be purchased by all eligible employees pursuant to
such Offering. In addition, in connection with each Offering which contains more
than one Exercise Date (as defined in the Offering), the Board or the Committee
may specify a maximum aggregate number of shares which may be purchased by all
eligible employees on any given Exercise Date under the Offering. If the
aggregate purchase of shares upon exercise of rights granted under the Offering
would exceed any such maximum aggregate number, the Board or the Committee shall
make a pro rata allocation of the shares available in as nearly a uniform manner
as shall be practicable and as it shall deem to be equitable.

         (b) The purchase price of stock acquired pursuant to rights granted
under the Plan shall be not less than the lesser of:

             (i)  an amount equal to eighty-five percent (85%) of the fair
market value of the stock on the Offering Date; or

             (ii) an amount equal to eighty-five percent (85%) of the fair
market value of the stock on the Exercise Date.

7.       Participation; Withdrawal; Termination.

         (a) An eligible employee may become a participant in an Offering by
delivering a participation agreement to the Company within the time specified in
the Offering, in such form as the Company provides. Each such agreement shall
authorize payroll deductions of up to fifteen percent (15%) (or such lower
percentage as the Board determines for a particular Offering) of such employee's
Earnings during the Purchase Period. "Earnings" is defined as an employee's
total compensation, including all salary, wages and other remuneration paid to
an employee (including amounts elected to be deferred by the employee, that
would otherwise have been paid, under any cash or deferred arrangement
established by the Company), overtime pay, commissions, bonuses, profit sharing,
and any special payments for extraordinary services,

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provided, however, that the Board in its sole discretion may limit the above
definition from time to time with respect to each Offering. The payroll
deductions made for each participant shall be credited to an account for such
participant under the Plan and shall be deposited with the general funds of the
Company. A participant may reduce, increase or begin such payroll deductions
after the beginning of any Purchase Period only as provided for in the Offering.
A participant may make additional payments into his or her account only if
specifically provided for in the Offering and only if the participant has not
had the maximum amount withheld during the Purchase Period.

         (b) At any time during a Purchase Period a participant may terminate
his or her payroll deductions under the Plan and withdraw from the Offering by
delivering to the Company a notice of withdrawal in such form as the Company
provides. Such withdrawal may be elected at any time prior to the end of the
Purchase Period. Upon such withdrawal from the Offering by a participant, the
Company shall distribute to such participant all of his or her accumulated
payroll deductions (reduced to the extent, if any, such deductions have been
used to acquire stock for the participant) under the Offering, without interest
unless the terms of the Offering specifically so provide, and such participant's
interest in that Offering shall be automatically terminated. A participant's
withdrawal from an Offering will have no effect upon such participant's
eligibility to participate in any other Offerings under the Plan but such
participant will be required to deliver a new participation agreement in order
to participate in subsequent Offerings under the Plan.

         (c) Rights granted pursuant to any Offering under the Plan shall
terminate immediately upon cessation of any participating employee's employment
with the Company or an Affiliate, for any reason, and the Company shall
distribute to such terminated employee all of his or her accumulated payroll
deductions (reduced to the extent, if any, such deductions have been used to
acquire stock for the terminated employee) under the Offering, without interest
unless the terms of the Offering specifically so provide.

         (d) Rights granted under the Plan shall not be transferable otherwise
than by will or the laws of descent and distribution, or by a beneficiary
designation as provided below and, otherwise during his or her lifetime, shall
be exercisable only by the person to whom such rights are granted.

             (i)    A participant under the Plan may file a written designation
of a beneficiary who is to receive any shares and/or cash, if any, from the
participant's account under the Plan in the event of such participant's death
subsequent to the end of an Offering but prior to delivery to the participant of
such shares and cash. In addition, a participant may file a written designation
of a beneficiary who is to receive any cash from the participant's account under
the Plan in the event of such participant's death during an Offering.

             (ii)   The participant may change such designation of beneficiary
at any time by written notice. In the event of the death of a participant and in
the absence of a beneficiary validly designated under the Plan who is living at
the time of such participant's death, the Company shall deliver such shares
and/or cash to the executor or administrator of the estate of the participant,
or if no such executor or administrator has been appointed (to the knowledge of
the Company), the Company, in its sole discretion, may deliver such shares
and/or cash to the

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spouse or to any one or more dependents or relatives of the participant, or if
no spouse, dependent or relative is known to the Company, then to such other
person as the Company may designate.

8.       Exercise.

         (a) On each exercise date as defined in the relevant Offering (an
"Exercise Date"), each participant's accumulated payroll deductions (without any
increase for interest unless the terms of the Offering specifically so provide)
will be applied to the purchase of whole shares of stock of the Company, up to
the maximum number of shares permitted pursuant to the terms of the Plan and the
applicable Offering, at the purchase price specified in the Offering. No
fractional shares shall be issued upon the exercise of rights granted under the
Plan. The amount, if any, of accumulated payroll deductions remaining in each
participant's account after the purchase of shares which is less than the amount
required to purchase one share of stock on the final Exercise Date of an
Offering shall be held in each such participant's account for the purchase of
shares under the next Offering under the Plan, unless such participant withdraws
from such next Offering, as provided in subparagraph 7(b), or is no longer
eligible to be granted rights under the Plan, as provided in paragraph 5, in
which case such amount shall be distributed to the participant after said final
Exercise Date, without interest unless the terms of the Offering specifically so
provide. The amount, if any, of accumulated payroll deductions remaining in any
participant's account after the purchase of shares which is equal to the amount
required to purchase whole shares of stock on the final Exercise Date of an
Offering shall be distributed in full to the participant after such Exercise
Date, without interest unless the terms of the Offering specifically so provide.

         (b) No rights granted under the Plan may be exercised to any extent
unless the Plan (including rights granted thereunder) is covered by an effective
registration statement pursuant to the Securities Act of 1933, as amended. If on
an Exercise Date of any Offering hereunder the Plan is not so registered, no
rights granted under the Plan or any Offering shall be exercised on said
Exercise Date and all payroll deductions accumulated during the Purchase Period
(reduced to the extent, if any, such deductions have been used to acquire stock)
shall be distributed to the participants, without interest unless the terms of
the Offering specifically so provide.

9.       Covenants of the Company.

         (a) During the terms of the rights granted under the Plan, the Company
shall keep available at all times the number of shares of stock required to
satisfy such rights.

         (b) The Company shall seek to obtain from each regulatory commission or
agency having jurisdiction over the Plan such authority as may be required to
issue and sell shares of stock upon exercise of the rights granted under the
Plan. If, after reasonable efforts, the Company is unable to obtain from any
such regulatory commission or agency the authority which counsel for the Company
deems necessary for the lawful issuance and sale of stock under the Plan, the
Company shall be relieved from any liability for failure to issue and sell stock
upon exercise of such rights unless and until such authority is obtained.

10.      Use of Proceeds from Stock.

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         Proceeds from the sale of stock pursuant to rights granted under the
Plan shall constitute general funds of the Company.

11.      Rights as a Stockholder.

         A participant shall not be deemed to be the holder of, or to have any
of the rights of a holder with respect to, any shares subject to rights granted
under the Plan unless and until certificates representing such shares shall have
been issued.

12.      Adjustments upon Changes in Stock.

         (a) If any change is made in the stock subject to the Plan, or subject
to any rights granted under the Plan (through merger, consolidation,
reorganization, recapitalization, stock dividend, dividend in property other
than cash, stock split, liquidating dividend, combination of shares, exchange of
shares, change in corporate structure or otherwise), the Plan and outstanding
rights will be appropriately adjusted in the class(es) and maximum number of
shares subject to the Plan and the class(es) and number of shares and price per
share of stock subject to outstanding rights.

         (b) In the event of: (i) a dissolution or liquidation of the Company;
(ii) a merger or consolidation in which the Company is not the surviving
corporation; (iii) a reverse merger in which the Company is the surviving
corporation but the shares of the Company's Common Stock outstanding immediately
preceding the merger are converted by virtue of the merger into other property,
whether in the form of securities, cash or otherwise; or (iv) any other capital
reorganization in which more than fifty percent (50%) of the shares of the
Company entitled to vote are exchanged, then, as determined by the Board in its
sole discretion (A) any surviving corporation may assume outstanding rights or
substitute similar rights for those under the Plan, (B) such rights may continue
in full force and effect, or (C) participants' accumulated payroll deductions
may be used to purchase Common Stock immediately prior to the transaction
described above and the participants' rights under the ongoing Offering
terminated.

13.      Amendment of the Plan.

         (a) The Board at any time, and from time to time, may amend the Plan.
However, except as provided in paragraph 12 relating to adjustments upon changes
in stock, no amendment shall be effective unless approved by the stockholders of
the Company if such modification requires stockholder approval in order for the
Plan to obtain employee stock purchase plan treatment under Section 423 of the
Code or to comply with the requirements of Rule 16b-3 promulgated under the
Securities Exchange Act of 1934, as amended, or any Nasdaq or securities
exchange listing requirements. It is expressly contemplated that the Board may
amend the Plan in any respect the Board deems necessary or advisable to provide
eligible employees with the maximum benefits provided or to be provided under
the provisions of the Code and the regulations promulgated thereunder relating
to employee stock purchase plans and/or to bring the Plan and/or rights granted
under it into compliance therewith.

         (b) Rights and obligations under any rights granted before amendment of
the Plan shall not be altered or impaired by any amendment of the Plan, except
with the consent of the person to whom such rights were granted.

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14.      Termination or Suspension of the Plan.

         (a) The Board may suspend or terminate the Plan at any time. No rights
may be granted under the Plan while the Plan is suspended or after it is
terminated.

         (b) Rights and obligations under any rights granted while the Plan is
in effect shall not be altered or impaired by suspension or termination of the
Plan, except with the consent of the person to whom such rights were granted.

15.      Effective Date of Plan.

         The Plan shall become effective as determined by the Board, but no
rights granted under the Plan shall be exercised unless and until the Plan has
been approved by the stockholders of the Company.

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                                                                    Exhibit 10.4

                            COR THERAPEUTICS, INC.
                1994 NON-EMPLOYEE DIRECTORS' STOCK OPTION PLAN

                         (Adopted on January 21, 1994)
                  (Approved by Stockholders on May 20, 1994)
                         (Amended on January 24, 1997)
                          (Amended on March 19, 1999)
             (Adjusted for 2-for-1 Stock Split on August 15, 2000)
                        (Amended on February 14, 2001)

                            Termination Date: None

1.   Purpose.

     (a) The purpose of the 1994 Non-Employee Directors' Stock Option Plan (the
"Plan") is to provide a means by which each director of COR Therapeutics, Inc.,
a Delaware corporation (the "Company"), who is not otherwise an employee or a
consultant of the Company or of any Affiliate of the Company (each such person
being hereafter referred to as a "Non-Employee Director") will be given an
opportunity to purchase stock of the Company.

     (b) The word "Affiliate" as used in the Plan means any parent corporation
or subsidiary corporation of the Company as those terms are defined in Sections
424(e) and (f), respectively, of the Internal Revenue Code of 1986, as amended
from time to time (the "Code").

     (c) The word "Fair Market Value" as used in the Plan means, as of any date,
the average of the high and low sales prices of a share of the Company's common
stock as quoted on the National Market System of the National Association of
Securities Dealers, Inc. Automated Quotation System, on the last market trading
day prior to the day of determination, as reported in The Wall Street Journal or
such other source as the Board of Directors of the Company (the "Board") deems
reliable.

     (d) The Company, by means of the Plan, seeks to retain the services of
persons now serving as Non-Employee Directors of the Company, to secure and
retain the services of persons capable of serving in such capacity, and to
provide incentives for such persons to exert maximum efforts for the success of
the Company.

2.   Administration.

     (a) The Plan shall be administered by the Board unless and until the Board
delegates administration to a committee, as provided in subparagraph 2(b).

     (b) The Board may delegate administration of the Plan to a committee
composed of two (2) or more members of the Board (the "Committee"), all of the
members of which Committee may (but need not) be, in the discretion of the
Board, "non-employee directors" within the meaning of Rule 16b-3 promulgated
under the Securities Exchange Act of 1934, as amended (the "Exchange Act"). If
administration is delegated to a Committee, the Committee shall have, in
connection with the administration of the Plan, the powers theretofore possessed
by

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the Board, subject, however, to such resolutions, not inconsistent with the
provisions of the Plan, as may be adopted from time to time by the Board. The
Board may abolish the Committee at any time and revest in the Board the
administration of the Plan.

3.   Shares Subject To The Plan.

     (a) Subject to the provisions of paragraph 10 relating to adjustments upon
changes in stock, the stock that may be sold pursuant to options granted under
the Plan shall not exceed in the aggregate seven hundred thousand (700,000)
shares/1/ of the Company's common stock. If any option granted under the Plan
shall for any reason expire or otherwise terminate without having been exercised
in full, the stock not purchased under such option shall again become available
under the Plan.

     (b) The stock subject to the Plan may be unissued shares or reacquired
shares, bought on the market or otherwise.

4.   Eligibility.

     Options shall be granted only to Non-Employee Directors of the Company.

5.   Non-Discretionary Grants.

     (a) Upon the date of the approval of the Plan by the Board (the "Adoption
Date"), each person who is then a Non-Employee Director shall be granted an
option to purchase fifty thousand (50,000) shares/2/ of common stock of the
Company on the terms and conditions set forth herein (an "Initial Grant").

     (b) Each person who is, after the Adoption Date, elected for the first time
to be a Non-Employee Director shall, upon the date of such person's initial
election to be a Non-Employee Director by the Board or stockholders of the
Company, be granted an Initial Grant.

     (c) Each person who, on or after March 19, 1999, is serving as a
Non-Employee Director shall be granted options to purchase twenty thousand
(20,000) shares/3/ of common stock of the Company on the terms and conditions
set forth herein (i) on the date of the first Board meeting held both on or
after March 19, 1999 and after the date on which the Non-Employee Director has
completed three (3) years of service as a director of the Company; and (ii)
every two years thereafter on the anniversary date of the grant made under the
foregoing clause (i) (each grant described in clauses (i) and (ii), a
"Supplemental Grant").

________________
/1/ Pursuant to subparagraph 10(a), the aggregate of 200,000 shares of common
stock in the share reserve was adjusted to 400,000 shares of common stock to
reflect the 2-for-1 stock split on August 15, 2000. On February 14, 2001 the
Board of Directors increased this number by 300,000 shares, to a total aggregate
of 700,000 shares of common stock.

/2/ Pursuant to subparagraph 10(a), the 25,000 shares of common stock were
adjusted to 50,000 shares of common stock to reflect the 2-for-1 stock split on
August 15, 2000.

/3/ Pursuant to subparagraph 10(a), the 10,000 shares of common stock were
adjusted to 20,000 shares of common stock to reflect the 2-for-1 stock split on
August 15, 2000.

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6.   Option Provisions.

     Each option shall contain the following terms and conditions:

     (a) The term of each option commences on the date it is granted and, unless
sooner terminated as set forth herein, expires on the date ("Expiration Date")
ten (10) years from the date of grant. If the optionee's service as a
Non-Employee Director of the Company terminates for any reason or for no reason,
the option shall terminate on the earlier of the Expiration Date or the date
three (3) months following the date of termination of service; provided,
however, that (i) if such termination is due to such person's permanent and
total disability, within the meaning of Section 422(c)(6) of the Code, the
option shall terminate on the earlier of the Expiration Date or twelve (12)
months following such termination; or (ii) if such termination of service is due
to the optionee's death, the option shall terminate on the earlier of the
Expiration Date or eighteen (18) months following the date of the optionee's
death. In any and all circumstances, an option may be exercised following
termination of the optionee's service as a Non-Employee Director of the Company
only as to that number of shares as to which it was exercisable on the date of
termination of such service under the provisions of subparagraph 6(e).

     (b) The exercise price of each option shall be one hundred percent (100%)
of the Fair Market Value of the stock subject to such option on the date such
option is granted.

     (c) Payment of the exercise price of each option is due in full in cash
upon any exercise when the number of shares being purchased upon such exercise
is less than two thousand (2,000) shares;/4/ but when the number of shares being
purchased upon an exercise is two thousand (2,000) or more shares,/5/ the
optionee may elect to make payment of the exercise price under one of the
following alternatives:

         (i)   Payment of the exercise price per share in cash at the time of
exercise; or

         (ii)  Provided that at the time of the exercise the Company's common
stock is publicly traded and quoted regularly in The Wall Street Journal,
payment by delivery of shares of common stock of the Company already owned by
the optionee, held for the period required to avoid a charge to the Company's
reported earnings, and owned free and clear of any liens, claims, encumbrances
or security interest, which common stock shall be valued at Fair Market Value
(with the "day of determination" being the date of exercise); or

         (iii) Payment by a combination of the methods of payment specified in
subparagraph 6(c)(i) and 6(c)(ii) above; or

         (iv)  Payment pursuant to a program developed under Regulation T as
promulgated by the Federal Reserve Board which results in the receipt of cash
(or check) by the Company prior to the issuance of shares of the Company's
common stock.

_______________
/4/ Pursuant to subparagraph 10(a), the 1,000 shares of common stock were
adjusted to 2,000 shares of common stock to reflect the 2-for-1 stock split on
August 15, 2000.

/5/ Pursuant to subparagraph 10(a), the 1,000 shares of common stock were
adjusted to 2,000 shares of common stock to reflect the 2-for-1 stock split on
August 15, 2000.

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     (d) An option shall not be transferable except by will or by the laws of
descent and distribution or pursuant to a domestic relations order, and shall be
exercisable during the lifetime of the person to whom the option is granted only
by such person or by his or her guardian or legal representative, unless
otherwise specified in the option, in which case the option may be transferred
upon such terms and conditions as are set forth in the option, as the Board or
the Committee shall determine in its discretion at the time of grant. The person
to whom the option is granted may, by delivering written notice to the Company,
in a form satisfactory to the Company, designate a third party who, in the event
of the death of the optionee, shall thereafter be entitled to exercise the
option.

     (e) Each Initial Grant shall become exercisable in installments over a
period of sixty (60) months from the date of grant at the rate of eight hundred
thirty-three and one-third (833 1/3) shares/6/ per month in sixty (60) equal
monthly installments commencing on the date one month after the date of grant of
the option, provided that the optionee has, during the entire period prior to
such vesting date, continuously served as a Non-Employee Director of the
Company, whereupon such option shall become fully exercisable in accordance with
its terms with respect to that portion of the shares represented by that
installment. Each Supplemental Grant shall be fully vested and exercisable on
the date on which it is granted.

     (f) The Company may require any optionee, or any person to whom an option
is transferred under subparagraph 6(d), as a condition of exercising any such
option: (i) to give written assurances satisfactory to the Company as to the
optionee's knowledge and experience in financial and business matters; and (ii)
to give written assurances satisfactory to the Company stating that such person
is acquiring the stock subject to the option for such person's own account and
not with any present intention of selling or otherwise distributing the stock.
These requirements, and any assurances given pursuant to such requirements,
shall be inoperative if (i) the issuance of the shares upon the exercise of the
option has been registered under a then-currently-effective registration
statement under the Securities Act of 1933, as amended (the "Securities Act"),
or (ii), as to any particular requirement, a determination is made by counsel
for the Company that such requirement need not be met in the circumstances under
the then-applicable securities laws. The Company may, upon advice of counsel to
the Company, place legends on stock certificates issued under the Plan as such
counsel deems necessary or appropriate in order to comply with applicable
securities laws, including, but not limited to, legends restricting the transfer
of the stock.

     (g) Notwithstanding anything to the contrary contained herein, an option
may not be exercised unless the shares issuable upon exercise of such option are
then registered under the Securities Act or, if such shares are not then so
registered, the Company has determined that such exercise and issuance would be
exempt from the registration requirements of the Securities Act.

________________
/6/ Pursuant to subparagraph 10(a), each monthly installment of 416 2/3 shares
of common stock was adjusted to 833 1/3 shares of common stock to reflect the 2-
for-1 stock split on August 15, 2000.

                                       4
<PAGE>

7.   Covenants Of The Company.

     (a) Subject to the provisions of subparagraph 7(b) hereof, during the terms
of the options granted under the Plan, the Company shall keep available at all
times the number of shares of stock required to satisfy such options.

     (b) Notwithstanding the provisions of subparagraph 7(a) hereof, at any such
time or times that the number of shares of common stock reserved for issuance
under the Plan pursuant to subparagraph 3(a) hereof that have been approved by
the stockholders of the Company are insufficient to make a timely
non-discretionary Initial Grant and/or a Supplemental Grant as specified in
paragraph 5 hereof (a "Grant"), then, without any further action of the Board,
such Grant shall be made in the following manner:

         (i)   The number of shares of common stock remaining in the share
reserve of the Plan, as provided in subparagraph 3(a) hereof, that have been
approved by the stockholders of the Company shall be applied to the Grants on a
pro-rated basis.

         (ii)  To the extent that there are insufficient shares of
stockholder-approved common stock available under the Plan to cover the Grants,
any additional number of shares of common stock required for the Grants shall be
deemed to have been made under the COR Therapeutics, Inc. 1991 Equity Incentive
Plan ("Equity Incentive Plan") and shall be applied to the Grants on a pro-rated
basis to the extent that such shares of common stock remaining in the share
reserve of the Equity Incentive Plan, as provided in subparagraph 3(a) of the
Equity Incentive Plan, have been approved by the stockholders of the Company.
Notwithstanding the foregoing, no Grants shall be made under the Plan or the
Equity Incentive Plan pursuant to paragraph 5 which give the right to purchase
fractional shares.

         (iii) The Grants otherwise shall be made on the terms and conditions
specified in paragraph 6 hereof.

         (iv)  To the extent that there are insufficient shares of
stockholder-approved common stock available under both the Plan and the Equity
Incentive Plan to cover the Grants, the Grants shall be delayed, in whole or in
part, as the case may be, until such time as shares of stockholder-approved
common stock under the Plan and/or the Equity Incentive Plan are available to
cover the Grants.

         (v)   In the event of any conflict between the terms and conditions of
the Plan and the Equity Incentive Plan, the terms and conditions of the Plan
shall control.

         (vi)  Notwithstanding anything in the Plan or the Equity Incentive Plan
to the contrary, the terms and conditions of the Plan shall survive the
termination of the Plan as to any Grant made pursuant to this subparagraph 7(b).

     (c) The Company shall seek to obtain from each regulatory commission or
agency having jurisdiction over the Plan such authority as may be required to
issue and sell shares of stock upon exercise of the options granted under the
Plan; provided, however, that this undertaking shall not require the Company to
register under the Securities Act either the Plan,

                                       5
<PAGE>

any option granted under the Plan, or any stock issued or issuable pursuant to
any such option. If, after reasonable efforts, the Company is unable to obtain
from any such regulatory commission or agency the authority which counsel for
the Company deems necessary for the lawful issuance and sale of stock under the
Plan, the Company shall be relieved from any liability for failure to issue and
sell stock upon exercise of such options.

8.   Use Of Proceeds From Stock.

     Proceeds from the sale of stock pursuant to options granted under the Plan
shall constitute general funds of the Company.

9.   Miscellaneous.

     (a) Neither an optionee nor any person to whom an option is transferred
under subparagraph 6(d) shall be deemed to be the holder of, or to have any of
the rights of a holder with respect to, any shares subject to such option unless
and until such person has satisfied all requirements for exercise of the option
pursuant to its terms.

     (b) Throughout the term of any option granted pursuant to the Plan, the
Company shall make available to the holder of such option, not later than one
hundred twenty (120) days after the close of each of the Company's fiscal years
during the option term, upon request, such financial and other information
regarding the Company as comprises the annual report to the stockholders of the
Company provided for in the Bylaws of the Company and such other information
regarding the Company as the holder of such option may reasonably request.

     (c) Nothing in the Plan or in any instrument executed pursuant thereto
shall confer upon any Non-Employee Director any right to continue in the service
of the Company or any Affiliate or shall affect any right of the Company, its
Board or stockholders or any Affiliate to terminate the service of any
Non-Employee Director with or without cause.

     (d) No Non-Employee Director, individually or as a member of a group, and
no beneficiary or other person claiming under or through such person, shall have
any right, title or interest in or to any option reserved for the purposes of
the Plan except as to such shares of common stock, if any, as shall have been
reserved for such person pursuant to an option granted to such person.

     (e) In connection with each option granted pursuant to the Plan, it shall
be a condition precedent to the Company's obligation to issue or transfer shares
to a Non-Employee Director, or to evidence the removal of any restrictions on
transfer, that such Non-Employee Director make arrangements satisfactory to the
Company to insure that the amount of any federal or other withholding tax
required to be withheld with respect to such sale or transfer, or such removal
or lapse, is made available to the Company for timely payment of such tax.

10.  Adjustments Upon Changes In Stock.

     (a) If any change is made in the stock subject to the Plan, or subject to
any option granted under the Plan (through merger, consolidation,
reorganization, recapitalization, stock

                                       6
<PAGE>

dividend, dividend in property other than cash, stock split, liquidating
dividend, combination of shares, exchange of shares, change in corporate
structure or otherwise), the Plan and outstanding options will be appropriately
adjusted in the class(es) and maximum number of shares subject to the Plan and
the class(es) and number of shares and price per share of stock subject to
outstanding options.

     (b) In the event of: (i) a merger or consolidation in which the Company is
not the surviving corporation; (ii) a reverse merger in which the Company is the
surviving corporation but the shares of the Company's common stock outstanding
immediately preceding the merger are converted by virtue of the merger into
other property, whether in the form of securities, cash or otherwise; or (iii)
any other capital reorganization in which more than fifty percent (50%) of the
shares of the Company entitled to vote are exchanged, then any surviving
corporation, other than the Company, shall assume any options outstanding under
the Plan or shall substitute similar options for those outstanding under the
Plan or, if the Company is the surviving corporation, such options shall
continue in full force and effect.

11.  Amendment Of The Plan.

     (a) The Board at any time, and from time to time, may amend the Plan.
Except as provided in paragraph 10 relating to adjustments upon changes in
stock, no amendment shall be effective unless approved by the stockholders of
the Company to the extent stockholder approval is necessary for the Plan to
satisfy the requirements of Rule 16b-3 under the Exchange Act or any Nasdaq or
securities exchange listing requirements.

     (b) Rights and obligations under any option granted before any amendment of
the Plan shall not be impaired by such amendment unless (i) the Company requests
the consent of the person to whom the option was granted and (ii) such person
consents in writing.

     (c) The Board at any time, and from time to time, may amend the terms of
any one or more options; provided, however, that the rights and obligations
under any option shall not be impaired by any such amendment unless (i) the
Company requests the consent of the person to whom the option was granted and
(ii) such person consents in writing.

12.  Termination Or Suspension Of The Plan.

     (a) The Board may suspend or terminate the Plan at any time. No options may
be granted under the Plan while the Plan is suspended or after it is terminated.

     (b) Rights and obligations under any option granted while the Plan is in
effect shall not be altered or impaired by suspension or termination of the
Plan, except with the consent of the person to whom the option was granted.

13.  Effective Date Of Plan; Conditions Of Exercise.

     (a) The Plan shall become effective upon adoption by the Board of
Directors, subject to the condition subsequent that the Plan is approved by the
stockholders of the Company.

                                       7
<PAGE>

     (b) No option granted under the Plan shall be exercised or exercisable
unless and until the condition of subparagraph 13(a) above has been met.

                                       8

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