Document:

10.58a

    

    Second
      Amendment to Executive Employment Agreement

    

    This
      Second Amendment (the “Amendment”) is made on this 8th
      day of
      May, 2007, but as of the 23rd day of February, 2007 by and between Gene
      Logic
      Inc., a Delaware corporation (the “Company”), and Philip L. Rohrer, Jr. (the
“Executive”). 

    

    The
      parties to this amendment have previously entered into an Executive Employment
      Agreement dated October 11, 1999 that was amended by a First Amendment dated
      as
      of October 24, 2006 (said agreement and amendment being herein referred to
      collectively as the “Agreement”). 

    

    On
      February 22, 2007, the Company’s Board of Directors approved certain changes to
      the terms of the Executive’s Agreement and the Executive agreed to such terms
      and this amendment is being executed to document those changes and evidence
      the
      agreement of the parties to such terms. Terms not otherwise defined herein
      shall
      have the meanings as defined in the Agreement.

    

    

    Therefore,
      the parties to this amendment hereby agree as follows:

    

    
      	1.	
              Base
                Salary.
                Section 2 of the Agreement is hereby amended by adding a new sentence
                after the first sentence of Section 2 to read as follows:
                

            

    

    

    For
      calendar year 2007, Rohrer shall receive an annualized base salary of $275,000.
      

    

    
      	2.	
              Incentive
                Compensation.
                Subsection 4.1 is hereby amended by adding the following sentences
                at the
                end thereof as follows:

            

    

    

    For
      calendar year 2007, Rohrer shall receive incentive compensation of 50% of his
      base salary, payable within 2 1⁄2 months after the end of 2007, so long as
      Rohrer’s employment by the Company on a full -time basis continues through
      December 31, 2007. This payment is in lieu of any other cash bonus or cash
      incentive compensation payment from the Company for Rohrer’s work during 2007.
      If Rohrer’s employment by the Company on a full-time basis terminates prior to
      December 31, 2007, he shall not be entitled to any incentive compensation
      payment for his work in 2007 under this subsection, but may be entitled to
      compensation under Section X. 

    

    
      	3.	
              Severance
                Payment.
                Section X is hereby amended by adding a new bullet after the other
                bullets
                in subsection (a) as follows:

            

    

    

    
      	 	
              §

            	
              If
                employment of the Executive is terminated by the Company prior to
                the end
                of 2007 without cause, in addition to any other severance payment
                to which
                he is otherwise entitled, he will also receive, within fifteen days
                after
                termination of employment, a lump sum payment equal to the balance
                of his
                2007 salary and incentive compensation as if he had worked through
                December 31, 2007 that has not previously been
                paid.

            

    

    

    
      	4.	
              Additional
                Change of Control payment.
                Subsection (c) of Section X is hereby further amended by adding the
                following after the first sentence of such
                subsection:

            

    

    

    However,
      notwithstanding the preceding sentence or any conflicting or inconsistent terms
      of the Company’s Executive Severance Plan, if employment of the Executive is
      terminated by the Company prior to the end of 2007 without cause and if
      Executive is entitled to benefits under the Executive Severance Plan, in
      addition to any other severance payment to which he is otherwise entitled
      thereunder, the Executive will also receive, within fifteen days after
      termination of employment and
      becoming
      entitled to payment under the Executive Severance Plan, a lump sum payment
      equal
      to the balance of his 2007 salary and incentive compensation as if he had worked
      through December 31, 2007 that has not previously been paid, as described in
      subsection X(a) above.

    

    
      
         

      

      
         

        
          

        

      

      
         

      

    

     

    
      	5.	
              Term.
                Section 6 is hereby amended by adding a new sentence at the end of
                such
                subsection as follows:

            

    

    

    Notwithstanding
      the above, from and after February 22, 2007, the term of employment hereunder
      shall be for a period ending on December 31, 2007, subject to renewal by
      agreement of the parties, and, notwithstanding any stated term, Company may
      terminate this Agreement at any time as provided in Section 7, and subject
      to
      the terms of Section X. 

     

    
      	6.	
              Miscellaneous:

            

    

    Except
      as
      specifically provided herein, the Agreement remains in full force and effect
      and
      unmodified.

    

    To
      evidence their agreement to the terms of this Second Amendment, Executive has
      signed and Company has caused its duly authorized representative to sign this
      Second Amendment as of February 23, 2007

    

    
      	
              Gene
                Logic Inc.

               

              By:
                /s/
                Charles L. Dimmler, III

              Charles
                L. Dimmler, III

              CEO
                & President

            	
              Executive

               

              /s/
                Philip L. Rohrer, Jr.

              Philip
                L. Rohrer, Jr.Exhibit 10.80a

    10.80a

    

    GUARANTY
      OF LEASE

    

    FOR
      V ALUE
      RECEIVED, and in consideration for, and as an inducement to Oxbridge Development
      at Crown Pointe, L.C., a Maryland limited liability company, to consent to
      an
      assignment by merger of the lease for space at 610 Professional Drive,
      Gaithersburg, Md. 20879 dated as of June 22, 2001, as amended September 25,
      2001
      and as further amended in January, 2003 (such amendment being signed by Joseph
      Angle on behalf of the then tenant on January 21, 2003 and last initialed by
      Landlord on January 24, 2003) (the "Lease"), in which it is "Landlord" to GLA
      II
      Corp., a Delaware corporation (to be renamed TherImmune Research Corporation
      at
      the time of the merger) (“Tenant"), a wholly-owned subsidiary of the undersigned
      and successor in interest by merger to TherImmune Research Corporation, a
      Maryland corporation, the original tenant under the Lease, the undersigned,
      whether one or more, jointly and severally do hereby unconditionally guarantee
      to Landlord (i)l the punctual and full payment of all rents of every kind,
      additional rents and all other charges to be paid by Tenant under the Lease
      and
      (ii) the full and timely performance and observance of all the covenants,
      conditions, and agreements to be performed and observed by Tenant under the
      Lease. The undersigned shall indemnify, defend and hold harmless Landlord and
      its affiliates from any loss, damages or costs (including without limitation,
      the reasonable fees of Landlord's attorneys and court costs, but excluding
      any
      indirect, consequential, exemplary or punitive damages) arising out of any
      failure to pay the aforesaid rents and other charges or the failure to perform
      any of the aforesaid covenants, conditions and agreements under the Lease,
      except to the extent arising out of the negligence or intentional misconduct
      of
      Landlord or its agents or property manager. The undersigned further expressly
      agree that the validity of this Lease and the obligations of the undersigned
      hereunder shall in no way be terminated, affected or impaired by reason of
      any
      forbearances, settlements or compromises between Landlord and Tenant or the
      relief of Tenant from any of Tenant's obligations under the Lease by operation
      of law, such as the rejection or assignment of the Lease in connection with
      proceedings under any present or future provision of the federal Bankruptcy
      Act,
      or any similar law or statute of the United States or any state
      thereof.

    

    The
      undersigned further covenant and agree that this Guaranty of Lease shall be
      and
      remain in full force and effect as to any renewal, modification or extension
      of
      the Lease, whether or not known to or approved by the undersigned, but this
      Guaranty shall not remain in effect if the Tenant's interest in the Lease is
      assigned, with Landlord's written consent, to a third party which is not owned
      and controlled by the undersigned. In the event of any termination of the Lease
      by Landlord, the undersigned's liability hereunder shall not be terminated,
      but
      the undersigned shall be and remain fully liable for the performance of the
      Tenant's obligations, if any, under the Lease. If the undersigned shall,
      directly or indirectly, advance .any sums to Tenant, such sums and indebtedness
      shall be subordinate in all respects to the amounts then and thereafter due
      and
      owing by Tenant under the Lease.

    

    Wherever
      reference is made to the liability of Tenant in the Lease, such reference shall
      he deemed likewise to refer to the undersigned, jointly and severally, with
      Tenant. The liability of the undersigned for the obligations of Tenant under
      the
      Lease shall be primary, absolute and unconditional. In any right of action
      which
      shall accrue to Landlord under the Lease, Landlord may, at Landlord's option,
      proceed against any one or more of the undersigned and/or Tenant, jointly or
      severally, and .may proceed against any one or more of the undersigned without
      having demanded performance of, commenced any action against or having obtained
      any judgment against Tenant The undersigned hereby expressly waive: (i) notice
      of acceptance of this Guaranty of Lease and of presentment, demand and protest;
      and (ii) notice to the undersigned of any default hereunder or under the Lease;
      provided, however that this waiver shall not constitute a waiver of any
      obligation of the Landlord pursuant to the Lease to give Tenant notice and
      an
      opportunity to cure defaults under the Lease. This Guaranty of Lease is a
      guaranty of payment and not a guaranty of collection. The undersigned agree
      that
      in the event this Guaranty of Lease shall be enforced by suit or otherwise,
      and
      the Landlord shall prevail in any such action, the undersigned will reimburse
      the Landlord, upon demand, for an expenses incurred in connection therewith,
      including, without limitation, reasonable attorneys' fees.

    

    
      
         

      

      
         

        
          

        

      

      
         

      

    

     

    The
      undersigned hereby waive, to the maximum extent permitted bylaw, any statute.
      of
      limitations affecting the enforcement of this Guaranty of Lease.

    

    THE
      UNDERSIGNED HEREBY KNOWINGLY, VOLUNTARILY AND INTENTIONALLY WAIVE THE RIGHT
      TO A
      TRIAL BY JURY IN RESPECT OF ANY LITIGATION BASED HEREON, ARISING OUT OF, UNDER
      OR IN CONNECTION WITH THIS GUARANTY OF LEASE OR ANY DOCUMENTS CONTEMPLATED
      TO BE
      EXECUTED IN CONNECTION HEREWITH OR ANY COURSE OF CONDUCT, COURSE OF DEALINGS,
      STATEMENTS (WHETHER ORAL OR WRITTEN) OR ACTIONS OF THE UNDERSIGNED OR LANDLORD
      ARISING OUT OR RELATED IN ANY MANNER WITH THIS GUARANTY OF LEASE (INCLUDING
      WITHOUT LIMITATION, ANY ACTION TO RESCIND OR CANCEL THIS GUARANTY OF LEASE
      OR
      ANY CLAIMS OR DEFENSES ASSERTING THAT THIS GUARANTY OF LEASE WAS FRAUDULENTLY
      INDUCED OR IS OTHERWISE VOID OR VOIDABLE). THIS WAIVER IS A MATERIAL INDUCEMENT
      FOR LANDLORD TO CONSENT TO THE ASSIGNMENT OF THE LEASE AS DESCRIBED
      ABOVE.

    

    The
      undersigned hereby assign to Landlord any rights the undersigned may have to
      file a claim and proof of claim in any bankruptcy or similar proceeding of
      Tenant and any awards of payments thereon to which the undersigned would
      otherwise be entitled.

    

    It
      is
      further agreed that all of the terms and provisions hereof shall inure to the
      benefit of and may be enforced by the respective heirs, executors, successors
      and assigns of Landlord and the holder of any mortgage to which the Lease may
      be
      subject and subordinate from time to time, and shall be binding upon the
      respective heirs, executors, successors and assigns of the undersigned. Landlord
      may, without notice, assign this Guaranty of Lease (in connection with the
      assignment of the Lease), and no such assignment shall increase or diminish
      the
      undersigned's liability under this Guaranty of Lease.

    

    In
      the
      event more than one person or entity executes this Guaranty of Lease, the
      liability of such signatories hereunder shall be joint and several. In the
      event
      only one person or entity executes this Guaranty of Lease, an provisions hereof
      which refer to more than one guarantor shall be automatically modified to refer
      to only one guarantor, and otherwise this Guaranty of Lease shall remain
      unmodified and in full force and effect

    

    It
      is
      understood that other agreements similar to this Guaranty of Lease may, at
      Landlord's sole option and discretion, be executed by other persons with respect
      to the Lease. This Guaranty of Lease shall be cumulative of any such agreements
      and the liabilities and obligations of the undersigned hereunder shall in no
      event be affected or diminished by reason of such other agreements. Moreover,
      in
      the event Landlord obtains the signature of more than one guarantor on this
      Guaranty of Lease or obtains additional guarantee agreements, or both, the
      undersigned agree that Landlord, in Landlord's sole discretion, may (i) compound
      or settle with anyone or more of the guarantors for such consideration as
      Landlord may deem proper, and (ii) release one or more of the guarantors from
      liability. The undersigned further agree that no such action shall impair the
      rights of Landlord to enforce the Lease against any remaining guarantor or
      guarantors, including the undersigned.

    

    The
      undersigned agree to execute and deliver to Landlord, from time to time, upon
      ten (10) business days notice from Landlord, a certificate addressed to
      Landlord, any mortgagee or prospective mortgagee, or any prospective purchase,
      certifying (i) that this Guaranty of Lease is unmodified and in full force
      and
      effect and (ii) to such other matters as Landlord may reasonably
      request.

    

    
      
         

      

      
         

        
          

        

      

      
         

      

    

     

    If
      any
      provision of this Guaranty of Lease or the application thereof to any person
      or
      circumstance shall, for any reason and to any extent, be invalid or
      unenforceable, the remainder of this Guaranty of Lease and the application
      of
      that provision to other persons or circumstances shall not be affected but
      rather shall be enforced to the fullest extent permitted by law.

    

    If
      the
      undersigned is a corporation (including any form of professional association),
      then each individual executing or attesting this Guaranty of Lease on behalf
      of
      such corporation covenants, warrants and represents that he or she is duly
      authorized to execute or attest and deliver this Guaranty of Lease on behalf
      of
      such corporation. If the undersigned is a partnership (general or limited)
      or
      limited liability company, then each individual executing this Guaranty of
      Lease
      on behalf of the partnership or company hereby covenants, warrants and
      represents that he or she is duly authorized to execute and deliver this
      Guaranty of Lease on behalf of the partnership or company in accordance with
      the
      partnership agreement or membership agreement, as the case may be, or an
      amendment thereto, now in effect.

    

    This
      Guaranty of Lease shall be governed by the Jaws of the State of Maryland,
      exc1uding choice of laws principles.

    

    EXECUTED
      UNDER SEAL as of the 1st day of April 2003

    

     

    
      	 	GUARANTOR:
	 	 
	 	GENE
              LOGIC INC., a Delaware corporation

    

     

    
      
        	
                 

              	
                By:

              	
                /s/
                  Philip L. Rohrer, Jr.

              	
              
	 
	
                 

              	
                Name:

              	
                Philip
                  L Rohrer, Jr.

              	
              
	 
	
                 

              	
                Title:

              	
                Chief
                  Financial Officer

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