Document:

Exhibit 10.5.1

 

SECOND AMENDED AND RESTATED UNIT SUBSCRIPTION
AGREEMENT

 

This SECOND
AMENDED AND RESTATED UNIT SUBSCRIPTION AGREEMENT (this “Agreement”) is made as of this
14th day of June, 2017, by and between Constellation Alpha Capital Corp., a company incorporated in the British
Virgin Islands with number 1884971(the “Company”), having its principal place of business at
Emerald View, Suite 400, 2054 Vista Parkway, West Palm Beach, FL 33411, and Centripetal, LLC (the
“Purchaser”).

 

WHEREAS, on September
21, 2015, the Company and the Purchaser entered into that certain Unit Subscription Agreement (the “Original Agreement”).

 

WHEREAS, on May 17,
2017, the Company and the Purchaser entered into that certain Amended and Restated Unit Subscription Agreement (the “Amended
and Restated Agreement”) amending and restating the Original Agreement, pursuant to which the Purchaser, on a private placement basis (the “Offering”), a agreed to
purchase 280,000 Initial Units of the Company (and up to an additional 37,500 Additional Units if the Over-Allotment Option is
exercised), each Initial Unit comprised of one ordinary share of the Company, no par value per share (the “Ordinary
Shares”), one warrant (the “Warrant”) to purchase one-half (1/2) of one ordinary share
(the “Warrant Shares”) to be governed by the Warrant Agreement (defined herein) and one right to receive
one-tenth (1/10) of one Ordinary Share (the “Right”) to be governed by the Rights Agreement (defined
herein), for a purchase price of $2,800,000, or $10.00 per Initial Unit. The Ordinary Shares underlying the Rights are hereinafter
referred to as the “Right Shares”.

 

WHEREAS, the
Company and the Purchaser desire to amend and restate the Amended and Restated Agreement in its entirety to provide for the
purchase of 368,750 Units (the “Initial
Units”) for an aggregate purchase price of $3,687,500 (or  a total of 425,000 units if the Over-Allotment Option is exercised in full for
an aggregate purchase price of $4,250,000 if the Over-Allotment option is exercised
in full), or $10.00 per Initial Unit;

  

NOW, THEREFORE, in
consideration of the promises and the mutual covenants hereinafter set forth and other good and valuable consideration, the receipt
and sufficiency of which are hereby acknowledged, the Company and the Purchaser hereby agree as follows:

 

1. Agreement to
Subscribe

 

1.1. Purchase and
Issuance of the Initial Units. For the aggregate sum of $3,687,500 (the “Initial Purchase Price”),
upon the terms and subject to the conditions of this Agreement, the Purchaser hereby agrees to purchase from the Company, and the
Company hereby agrees to sell to the Purchaser, on the Closing Date (as defined in Section 1.2) 368,750 Initial Units at $10.00
per Initial Unit.

 

In addition to the
foregoing, the Purchaser hereby agrees to purchase up to an additional 56,250 Units (“Additional Units”
and together with the Initial Units, the “Units”) at $10.00 per Additional Unit (such aggregate amount,
the “Additional Purchase Price” and together with the Initial Purchase Price, the “Purchase
Price”). The purchase and issuance of the Additional Units shall occur only in the event that the underwriters’
45-day over-allotment option (“Over-Allotment Option”) in the Offering is exercised in full or part.
The total number of Additional Units to be purchased hereunder shall be in the same proportion as the amount of the Over-Allotment
Option that is exercised. Each purchase of Additional Units shall occur simultaneously with the consummation of any portion of
the Over-Allotment Option.

 

1.2. Closing.
The closing (the “Closing”) of the Offering shall take place at the offices of Ellenoff Grossman
& Schole LLP, 1345 Avenue of the Americas, New York, New York, 10105 simultaneously with the consummation of the
Company’s initial public offering (“IPO”) of 12,500,000 units consisting of Ordinary Shares,
Rights and Warrants and the consummation of the exercise of all or any portion of the Over-Allotment Option (each a
“Closing Date”).

 

1.3. Delivery of
the Purchase Price. At least one business day prior to the closing date of the Company’s IPO, or the date of the closing
of the Over-Allotment Option, if any, the Purchaser agrees to deliver the Initial Purchase Price or Additional Purchase Price,
as the case may be, by certified bank check or wire transfer of immediately available funds denominated in United States Dollars
to Continental Stock Transfer & Trust Company (“CST”) to deposit such funds on the applicable Closing
Date to the trust account which will be established for the benefit of the Company’s public shareholders, managed pursuant
to that certain Investment Management Trust Agreement to be entered into by and between the Company and CST and into which substantially
all of the proceeds of the IPO will be deposited (the “Trust Account”). If the IPO is not consummated
within 14 days of the date the Initial Purchase Price is delivered to CST, the Initial Purchase Price shall be returned to the
Purchaser by certified bank check or wire transfer of immediately available funds denominated in United States Dollars, without
interest or deduction.

         

     

     

    

  

1.4. Delivery of
Unit Certificate. Upon the applicable Closing Date after delivery of the Purchase Price in accordance with Section 1.3, the
Purchaser shall become irrevocably entitled to receive a unit certificate representing the Units purchased hereunder. 

 

2. Representations
and Warranties of the Purchaser

 

The Purchaser represents
and warrants to the Company that:

 

2.1. No Government
Recommendation or Approval. It understands that no United States federal or state agency or similar agency of any other country
has passed upon or made any recommendation or endorsement of the Company, the Offering, the Units, the Warrants, the Rights, Warrant
Shares or Right Shares, or the Ordinary Shares underlying the Units (excluding the Warrant Shares and Right Shares, the “Unit
Shares” and, collectively with the Units, Warrant Shares and Right Shares, the “Securities”).

 

2.2. Organization. 
It is a company, validly existing and in good standing under the laws of its jurisdiction and possesses all requisite power and
authority necessary to carry out the transactions contemplated by this Agreement.

 

2.3. Private Offering.
It is an “accredited investor” as such term is defined in Rule 501(a) of Regulation D under the Securities Act of 1933,
as amended (the “Securities Act”). It acknowledges that the sale contemplated hereby is being made in reliance on a
private placement exemption to “Accredited Investors” within the meaning of Section 501(a) of Regulation D under the
Securities Act and similar exemptions under state law.

 

2.4. Authority.
This Agreement has been validly authorized, executed and delivered by the Purchaser and is a valid and binding agreement enforceable
in accordance with its terms, except as such enforceability may be limited by applicable bankruptcy, insolvency, fraudulent conveyance
or similar laws affecting the enforcement of creditors’ rights generally and subject to general principles of equity (regardless
of whether enforcement is sought in a proceeding at law or in equity).

 

2.5. No Conflicts.
The execution, delivery and performance of this Agreement and the consummation by the Purchaser of the transactions contemplated
hereby do not violate, conflict with or constitute a default under (i) the Purchaser’s organizational documents, (ii) any
agreement, indenture or instrument to which the Purchaser is a party or (iii) any law, statute, rule or regulation to which the
Purchaser is subject, or any agreement, order, judgment or decree to which the Purchaser is subject.

 

2.6. No Legal Advice
from Company. It acknowledges it has had the opportunity to review this Agreement and the transactions contemplated by this
Agreement and the other agreements entered into between the parties hereto with its own legal counsel and investment and tax advisors.
Except for any statements or representations of the Company made in this Agreement and the other agreements entered into between
the parties hereto, it is relying solely on such counsel and advisors and not on any statements or representations of the Company
or any of its representatives or agents for legal, tax or investment advice with respect to this investment, the transactions contemplated
by this Agreement or the securities laws of any jurisdiction.

 

2.7. Access to
Information; Independent Investigation. Prior to the execution of this Agreement, it has had the opportunity to ask questions
of and receive answers from representatives of the Company concerning an investment in the Company, as well as the finances, operations,
business and prospects of the Company, and the opportunity to obtain additional information to verify the accuracy of all information
so obtained. In determining whether to make this investment, it has relied solely on its own knowledge and understanding of the
Company and its business based upon its own due diligence investigation and the information furnished pursuant to this paragraph.
It understands that no person has been authorized to give any information or to make any representations which were not furnished
pursuant to this Section 2 and it has not relied on any other representations or information in making its investment decision,
whether written or oral, relating to the Company, its operations and/or its prospects.

 

2.8. Reliance on
Representations and Warranties. It understands the Units are being offered and sold to it in reliance on exemptions from the
registration requirements under the Securities Act, and analogous provisions in the laws and regulations of various states, and
that the Company is relying upon the truth and accuracy of the representations, warranties, agreements, acknowledgments and understandings
of the Purchaser set forth in this Agreement in order to determine the applicability of such provisions.

  

     

     

    

  

2.9. No Advertisements.
It is not subscribing for the Units as a result of or subsequent to any advertisement, article, notice or other communication published
in any newspaper, magazine, or similar media or broadcast over television or radio, or presented at any seminar or meeting.

 

2.10. Legend.
It acknowledges and agrees the certificates evidencing the Units and the Ordinary Shares, Warrants and Rights shall bear a restrictive
legend (the “Legend”), in form and substance as set forth in Section 4 hereof, prohibiting the offer,
sale, pledge or transfer of the securities, except (i) pursuant to an effective registration statement covering these securities
under the Securities Act or (ii) pursuant to any other exemptions from the registration requirements under the Securities
Act and such laws which, in the opinion of counsel for the Company, is available.

 

2.11. Experience,
Financial Capability and Suitability. It is (i) sophisticated in financial matters and is able to evaluate the risks and benefits
of the investment in the Securities and (ii) able to bear the economic risk of his investment in the Securities for an indefinite
period of time because the Securities have not been registered under the Securities Act and therefore cannot be sold unless subsequently
registered under the Securities Act or an exemption from such registration is available. It has substantial experience in evaluating
and investing in transactions of securities in companies similar to the Company so that it is capable of evaluating the merits
and risks of its investment in the Company and has the capacity to protect its own interests. It has substantial experience in
evaluating and investing in transactions of securities in companies similar to the Company so that it is capable of evaluating
the merits and risks of its investment in the Company and has the capacity to protect its own interests.

 

2.12. Investment
Purposes. It is purchasing the Securities solely for investment purposes, for its own account and not for the account or benefit
of any other person, and not with a view towards the distribution or dissemination thereof and it has no present arrangement to
sell the interest in the Securities to or through any person or entity.

 

2.13. Restrictions
on Transfer. It acknowledges and understands the Units are being offered in a transaction not involving a public offering in
the United States within the meaning of the Securities Act. The Securities have not been registered under the Securities Act, and,
if in the future, it decides to offer, resell, pledge or otherwise transfer the Securities, such Securities may be offered, resold,
pledged or otherwise transferred only (A) pursuant to an effective registration statement filed under the Securities Act,
(B) pursuant to an exemption from registration under Rule 144 promulgated under the Securities Act (“Rule 144”),
if available, or (C) pursuant to any other available exemption from the registration requirements of the Securities Act, and
in each case in accordance with any applicable securities laws of any state or any other jurisdiction. It agrees that if any transfer
of its Securities or any interest therein is proposed to be made, as a condition precedent to any such transfer, it may be required
to deliver to the Company an opinion of counsel satisfactory to the Company. Absent registration or another available exemption
from registration, it agrees it will not resell the Securities. It further acknowledges that because the Company is a shell company,
Rule 144 may not be available to it for the resale of the Securities until the one year anniversary following consummation of the
initial Business Combination (defined below) of the Company, despite technical compliance with the requirements of Rule 144 and
the release or waiver of any contractual transfer restrictions.

 

3. Representations
and Warranties of the Company

 

The Company represents
and warrants to the Purchaser that:

 

3.1. Valid Issuance
of Share Capital. The total number of all classes of share capital which the Company has authority to issue is (i) an unlimited
number of Ordinary Shares and (ii) an unlimited number of preferred shares. As of the date hereof, the Company has issued and outstanding
3,593,750 Ordinary Shares (of which 468,750 Ordinary Shares are subject to forfeiture as described in the registration statement
related to the IPO) and no preferred shares issued and outstanding. All of the issued share capital of the Company has been duly
authorized, validly issued, and are fully paid and non-assessable.

 

 

     

     

    

 

 

3.2. Title to Securities.
Upon issuance in accordance with, and payment pursuant to, the terms hereof, the warrant agreement to be entered into with a mutually
agreeable warrant agent on or prior to the closing of the IPO (“Warrant Agreement”), and that certain
rights agreement to be entered into with a mutual agreeable rights agent (the “Rights Agreement”), as
the case may be, each of the Warrants, Rights and the Ordinary Shares will be duly and validly issued, fully paid and non-assessable.
On the date of issuance of the Units, the Warrant Shares and Right Shares shall have been reserved for issuance. Upon issuance
in accordance with the terms hereof and the Warrant Agreement, the Purchaser will have or receive good title to the Warrant Shares,
free and clear of all liens, claims and encumbrances of any kind, and upon issuance in accordance with the terms hereof and the
Rights Agreement, the Purchaser will have or receive good title to the Right Shares, free and clear of all liens, claims and encumbrances
of any kind, other than (i) transfer restrictions hereunder and pursuant to the insider letter to be entered into on or prior to
the closing of the IPO (the “Insider Letter”) and (ii) transfer restrictions under federal and state
securities laws.

 

3.3. Organization
and Qualification. The Company has been duly incorporated and is validly existing as a British Virgin Islands business company
and has the requisite corporate power to own its properties and assets and to carry on its business as now being conducted.

 

3.4. Authorization;
Enforcement. (i) The Company has the requisite corporate power and authority to enter into and perform its obligations
under this Agreement and to issue the Securities in accordance with the terms hereof, (ii) the execution, delivery and performance
of this Agreement by the Company and the consummation by it of the transactions contemplated hereby have been duly authorized by
all necessary corporate action and no further consent or authorization of the Company or its Board of Directors or shareholders
is required, and (iii) this Agreement constitutes, and upon the execution and delivery thereof, the Warrants and Warrant Agreement
and the Rights and Rights Agreement will constitute, valid and binding obligations of the Company enforceable against the Company
in accordance with their respective terms, except as such enforceability may be limited by applicable bankruptcy, insolvency, fraudulent
conveyance, moratorium, reorganization, or similar laws relating to, or affecting generally the enforcement of, creditors’
rights and remedies or by equitable principles of general application and except as enforcement of rights to indemnity and contribution
may be limited by federal and state securities laws or principles of public policy.

 

3.5. No Conflicts.
The execution, delivery and performance of this Agreement and the consummation by the Company of the transactions contemplated
hereby do not (i) result in a violation of the Company’s Memorandum and Articles of Association, (ii) conflict
with, or constitute a default under any agreement, indenture or instrument to which the Company is a party or (iii) conflict with
any law statute, rule or regulation to which the Company is subject or any agreement, order, judgment or decree to which the Company
is subject. Other than any federal, state or foreign securities filings which may be required to be made by the Company subsequent
to the Closing, and any registration statement which may be filed pursuant thereto, the Company is not required under federal,
state or local law, rule or regulation to obtain any consent, authorization or order of, or make any filing or registration with,
any court or governmental agency or self-regulatory entity in order for it to perform any of its obligations under this Agreement
or issue the Units, the Warrants, the Rights or the Ordinary Shares underlying the Units, Warrants or Rights in accordance with
the terms hereof.

 

4. Legends

 

4.1. Legend.
The Company will issue the Units, the Warrants, the Rights and the Unit Shares, and when issued, the Warrant Shares and Right Shares,
purchased by the Purchaser, in the name of the Purchaser. The Securities will bear the following Legend and appropriate “stop
transfer” instructions:

 

THESE SECURITIES (i) HAVE NOT BEEN REGISTERED
UNDER THE UNITED STATES SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND THESE SECURITIES MAY NOT BE
OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED EXCEPT (A) PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT FILED UNDER THE SECURITIES
ACT, (B) PURSUANT TO AN EXEMPTION FROM REGISTRATION PROVIDED BY RULE 144 UNDER THE SECURITIES ACT (IF AVAILABLE) OR (C) PURSUANT
TO ANY OTHER EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT, IN EACH CASE IN ACCORDANCE WITH ANY APPLICABLE
SECURITIES LAWS OF ANY STATE OF THE UNITED STATES OR ANY OTHER JURISDICTION. HEDGING TRANSACTIONS INVOLVING THESE SECURITIES MAY
NOT BE CONDUCTED UNLESS IN COMPLIANCE WITH THE SECURITIES ACT.

 

     

     

    

  

“THE SECURITIES REPRESENTED BY THIS
CERTIFICATE ARE SUBJECT TO AN AGREEMENT BETWEEN CONSTELLATION ALPHA CAPITAL CORP. AND CENTRIPETAL, LLC AND MAY ONLY BE OFFERED,
SOLD, TRANSFERRED, PLEDGED OR OTHERWISE DISPOSED DURING THE TERM OF THE LOCKUP PURSUANT TO THE TERMS SET FORTH THEREIN.”

 

4.2. Purchaser’s
Compliance. Nothing in this Section 4 shall affect in any way the Purchaser’s obligations and agreements to comply
with all applicable securities laws upon resale of the Securities.

 

4.3. Company’s
Refusal to Register Transfer of the Securities. The Company shall refuse to register any transfer of the Securities, if in
the sole judgment of the Company such purported transfer would not be made (i) pursuant to an effective registration statement
filed under the Securities Act, or (ii) pursuant to an available exemption from the registration requirements of the Securities
Act.

 

4.4. Registration
Rights. The Purchaser will be entitled to certain registration rights which will be governed by a registration rights agreement
(“Registration Rights Agreement”) to be entered into with the Company on or prior to the closing of the
IPO.

 

5. Lockup

 

The Purchaser acknowledges
and agrees that the Units, the Warrants, the Rights the Unit Shares, the Warrant Shares and the Right Shares shall not be transferable,
saleable or assignable until after the consummation of an acquisition, share exchange, purchase of all or substantially all of
the assets of, or any other similar business combination with one or more businesses or entities (a “Business Combination”),
except to permitted transferees (as defined in the Insider Letter).

 

6. Securities Laws
Restrictions

 

The Purchaser agrees
not to sell, transfer, pledge, hypothecate or otherwise dispose of all or any part of the Securities unless, prior thereto (a) a
registration statement on the appropriate form under the Securities Act and applicable state securities laws with respect to the
Securities proposed to be transferred shall then be effective or (b) the Company shall have received an opinion from counsel
reasonably satisfactory to the Company, that such registration is not required because such transaction complies with the Securities
Act and the rules promulgated by the Securities and Exchange Commission thereunder and with all applicable state securities laws.

 

7. Waiver of Distributions
from Trust Account

 

In connection with
the Securities purchased pursuant to this Agreement, the Purchaser hereby waives any and all right, title, interest or claim of
any kind in or to any distributions from the Trust Account.

 

8. Rescission Right
Waiver and Indemnification

 

8.1. Rescission
Waiver. The Purchaser understands and acknowledges that an exemption from the registration requirements of the Securities Act
requires there be no general solicitation of purchasers of the Units. In this regard, if the Offering were deemed to be a general
solicitation with respect to the Units, the offer and sale of such Units may not be exempt from registration and, if not, the Purchaser
may have a right to rescind its purchase of the Units. In order to facilitate the completion of the Offering and in order to protect
the Company, its shareholders and the Trust Account from claims that may adversely affect the Company or the interests of its shareholders,
the Purchaser hereby agrees to waive, to the maximum extent permitted by applicable law, any claims, right to sue or rights in
law or arbitration, as the case may be, to seek rescission of its purchase of the Units as a result of the issuance of the Units
being deemed to be in violation of Section 5 of the Securities Act. The Purchaser acknowledges and agrees this waiver is being
made in order to induce the Company to sell the Units to the Purchaser. The Purchaser agrees the foregoing waiver of rescission
rights shall apply to any and all known or unknown actions, causes of action, suits, claims or proceedings (collectively, “Claims”)
and related losses, costs, penalties, fees, liabilities and damages, whether compensatory, consequential or exemplary, and expenses
in connection therewith, including reasonable attorneys’ and expert witness fees and disbursements and all other expenses
reasonably incurred in investigating, preparing or defending against any Claims, whether pending or threatened, in connection with
any present or future actual or asserted right to rescind the purchase of the Units hereunder or relating to the purchase of the
Units and the transactions contemplated hereby.

  

     

     

    

  

8.2. No Recourse
Against Trust Account. The Purchaser agrees not to seek recourse against the Trust Account for any reason whatsoever in connection
with its purchase of the Units or any Claim that may arise now or in the future.

 

8.3. Section 8
Waiver. The Purchaser agrees that to the extent any waiver of rights under this Section 8 is ineffective as a matter of law,
the Purchaser has offered such waiver for the benefit of the Company as an equitable right that shall survive any statutory disqualification
or bar that applies to a legal right. The Purchaser acknowledges the receipt and sufficiency of consideration received from the
Company hereunder in this regard.

 

9. Terms of the
Unit

 

The Units shall be
substantially identical to the Units offered in the IPO as set forth in the Underwriting Agreement, except the Units: (i) will
be subject to the transfer restrictions described herein, and (ii) are being purchased pursuant to an exemption from the registration
requirements of the Securities Act and will become freely tradable only after certain conditions are met or the resale of the Units
is registered under the Securities Act.

 

10. Governing Law;
Jurisdiction; Waiver of Jury Trial

 

This Agreement shall
be governed by and construed in accordance with the laws of the British Virgin Islands for agreements made and to be wholly performed
within such territory. The parties hereto hereby waive any right to a jury trial in connection with any litigation pursuant to
this Agreement and the transactions contemplated hereby.

 

11. Assignment;
Entire Agreement; Amendment

 

11.1. Assignment.
Neither this Agreement nor any rights hereunder may be assigned by any party to any other person other than by the Purchaser, without
the prior consent of the Company, to one or more persons agreeing to be bound by the terms hereof. Upon such assignment by a Purchaser,
the assignee(s) shall become Purchaser hereunder and have the rights and obligations provided for herein to the extent of such
assignment.

 

11.2. Entire Agreement.
This Agreement sets forth the entire agreement and understanding between the parties as to the subject matter hereof and supersedes
any and all prior discussions, agreements and understandings of any and every nature.

 

11.3. Amendment.
Except as expressly provided in this Agreement, neither this Agreement nor any term hereof may be amended, waived, discharged or
terminated other than by a written instrument signed by the party against whom enforcement of any such amendment, waiver, discharge
or termination is sought.

 

11.4. Binding upon
Successors. This Agreement shall be binding upon and inure to the benefit of the parties hereto and to their respective heirs,
legal representatives, successors and permitted assigns.

 

12. Notices; Indemnity

 

12.1 Notices.
All notices, requests, consents and other communications hereunder shall be in writing, shall be addressed to the receiving party’s
address set forth herein or to such other address as a party may designate by notice hereunder, and shall be either (a) delivered
by hand, (b) sent by overnight courier, or (c) sent by certified mail, return receipt requested, postage prepaid. All notices,
requests, consents and other communications hereunder shall be deemed to have been given either (i) if by hand, at the time of
the delivery thereof to the receiving party at the address of such party set forth above, (ii) if sent by overnight courier, on
the next business day following the day such notice is delivered to the courier service, or (iii) if sent by certified mail, on
the fifth business day following the day such mailing is made.

  

     

     

    

  

12.2 Indemnification.
Except as set forth in Section 8, each party shall indemnify the other party against any loss, cost or damages (including reasonable
attorney’s fees and expenses) incurred as a result of such party’s breach of any representation, warranty, covenant
or agreement set forth in this Agreement.

 

13. Counterparts

 

This Agreement may
be executed in one or more counterparts, all of which when taken together shall be considered one and the same agreement and shall
become effective when counterparts have been signed by each party and delivered to the other party, it being understood that both
parties need not sign the same counterpart.  In the event that any signature is delivered by facsimile transmission or any
other form of electronic delivery, such signature shall create a valid and binding obligation of the party executing (or on whose
behalf such signature is executed) with the same force and effect as if such signature page were an original thereof.

 

14. Survival; Severability

 

14.1. Survival.
The representations, warranties, covenants and agreements of the parties hereto shall survive the Closing until one (1) year following
the consummation of an initial Business Combination.

 

14.2. Severability.
In the event that any provision of this Agreement becomes or is declared by a court of competent jurisdiction to be illegal, unenforceable
or void, this Agreement shall continue in full force and effect without said provision; provided that no such severability
shall be effective if it materially changes the economic benefit of this Agreement to any party.

 

15. Headings

 

The titles and subtitles
used in this Agreement are used for convenience only and are not to be considered in construing or interpreting this Agreement.

 

16. Construction

 

The parties hereto
have participated jointly in the negotiation and drafting of this Agreement. If an ambiguity or question of intent or interpretation
arises, this Agreement will be construed as if drafted jointly by the parties hereto and no presumption or burden of proof will
arise favoring or disfavoring any party hereto because of the authorship of any provision of this Agreement. The words “include,”
“includes,” and “including” will be deemed to be followed by “without limitation.”
Pronouns in masculine, feminine, and neuter genders will be construed to include any other gender, and words in the singular form
will be construed to include the plural and vice versa, unless the context otherwise requires. The words “this Agreement,”
“herein,” “hereof,” “hereby,” “hereunder,” and words
of similar import refer to this Agreement as a whole and not to any particular subdivision unless expressly so limited. The parties
hereto intend that each representation, warranty, and covenant contained herein will have independent significance. If any party
hereto has breached any representation, warranty, or covenant contained herein in any respect, the fact that there exists another
representation, warranty or covenant relating to the same subject matter (regardless of the relative levels of specificity) which
such party hereto has not breached will not detract from or mitigate the fact that such party hereto is in breach of the first
representation, warranty, or covenant.

 

[remainder of page intentionally left blank]

  

     

     

    

  

This subscription is accepted by the Company
as of the date first written above.

 

	 	CONSTELLATION ALPHA CAPITAL CORP.
	 	 	 
	 	By:	/s/ Rajiv Shukla
	 	 	 
	 	Name: 	 Rajiv Shukla
	 	Title: 	Chief Executive Officer and Chairman of the Board

 

Accepted and agreed this

14th day of June, 2017

 

	CENTRIPETAL, LLC	 
	 	 	 
	By:	/s/ Rajiv Shukla	 
	Name:	Rajiv Shukla	 
	Title:	Authorized PersonExhibit 10.6.1

AMENDED AND RESTATED

UNIT SUBSCRIPTION AGREEMENT

 

This AMENDED AND RESTATED UNIT SUBSCRIPTION AGREEMENT
(this “Agreement”) is made as of this ____ day of June 2017, by and between Constellation Alpha
Capital Corp., a British Virgin Islands business company (the “Company”), having its principal place
of business at Emerald View, Suite 400, 2054 Vista Parkway, West Palm Beach, FL 33411, and Cowen Investments LLC (the “Purchaser”).

 

WHEREAS, the Company and the Purchaser entered
into that certain Unit Subscription Agreement, dated as of May 17, 2017 (the "Initial Agreement"), pursuant
to which the Purchaser agreed to purchase on a private placement basis (the "Offering"), an aggregate of
100,000 units of the Company, each such unit comprised of one ordinary share of the Company, no par value per share (the “Ordinary
Shares”), one right to receive one-tenth (1/10) of one share of common stock (the “Right”),
and one warrant (the “Warrant”) to purchase one-half of one Ordinary Share (the “Warrant
Shares”), for an aggregate purchase price of $1,000,000, or $10.00 per unit; and, in conjunction therewith, the Company
agreed to issue to the Purchaser 100,000 Ordinary Shares (the "Private Shares") for no additional consideration
(which Ordinary Shares shall be identical to the Ordinary Shares (the "Founder Shares") purchased by Centripetal,
LLC (the "Sponsor") prior to the Company’s initial public offering ("IPO"))
and, in connection therewith, the Sponsor agreed to forfeit by surrendering without consideration to the Company 100,000 Founder
Shares;

 

WHEREAS, simultaneously with the consummation
of the Company’s IPO of 12,500,000 units (the “Public Units”) consisting of Ordinary Shares, the
Rights and Warrants, the Sponsor agreed to purchase on a private placement basis an aggregate of 280,000 units (or 317,500 units
if the over-allotment option is exercised in full) that are identical to the units to be purchased by the Purchaser, for an aggregate
purchase price of $2,800,000 (or $3,175,000 if the over-allotment option is exercised in full), or $10.00 per unit;

 

WHEREAS, the Sponsor has now agreed to purchase
an additional 88,750 units (or 107,500 units if the over-allotment option is exercised in full) for a total of 368,750 units (or
a total of 425,000 units if the over-allotment option is exercised in full) (the “Founder Units”) for
an aggregate purchase price of $3,687,500 (or $4,250,000 if the over-allotment option is exercised in full), or $10.00 per Founder
Unit;

 

WHEREAS, as a result of the purchase by the Sponsor
of additional Founder Units, the Company and the Purchaser desire to amend and restate the Initial Agreement to provide for the
purchase by the Purchaser of an additional 36,250 units for a total of 136,250 units (the "Private Units")
for an aggregate purchase price of $1,362,500, or $10.00 per Private Unit;

 

WHEREAS, concurrently with the issuance of the
Private Units, the Company agrees to issue to the Purchaser 136,250 Ordinary Shares (the "Private Shares")
for no additional consideration, which Ordinary Shares shall be identical to the Ordinary Shares (the "Founder Shares")
purchased by the Sponsor prior to the Company’s IPO and, in connection therewith, the Sponsor shall forfeit by surrendering
without consideration to the Company 136,250 Founder Shares; and

 

WHEREAS, the Purchaser desires to purchase the
Private Units and the Company wishes to accept such subscription.

 

    	 	1	 

     

    

 

NOW, THEREFORE, in consideration of the promises
and the mutual covenants hereinafter set forth and other good and valuable consideration, the receipt and sufficiency of which
are hereby acknowledged, the Company and the Purchaser hereby agree as follows:

 

1. Agreement to Subscribe

 

1.1. Purchase and Issuance of the Private
Units; Issuance of Private Shares. For the aggregate sum of $1,362,500 (the “Purchase Price”), or
$10.00 per Private Unit, upon the terms and subject to the conditions of this Agreement, the Purchaser hereby agrees to purchase
from the Company, and the Company hereby agrees to sell to the Purchaser, on the Closing Date (as defined in Section 1.2) 136,250
Private Units, free and clear of any and all liens, claims, options, charges, pledges, security interests, voting agreements, voting
trusts, encumbrances, or restrictions of any nature (“Liens”) (other than restrictions under applicable
securities laws and the restrictions contained herein). Concurrently with the purchase of the Private Units by the Purchaser, the
Company agrees to issue to the Purchaser 136,250 Ordinary Shares, free and clear of any and all Liens (other than restrictions
under applicable securities laws and the restrictions contained herein).

  

1.2. Closing. The closing (the “Closing”)
of the subscription of the Private Units and the issuance of the Private Shares shall take place at the offices of Ellenoff Grossman
& Schole LLP, 1345 Avenue of the Americas, New York, New York, 10105 simultaneously with the consummation of the Company’s
IPO (such date, the “Closing Date”).

 

1.3. Delivery of the Purchase Price.
On the Closing Date, the Purchaser agrees to deliver the Purchase Price by certified bank check or wire transfer of immediately
available funds denominated in United States Dollars to Continental Stock Transfer & Trust Company, which funds shall be deposited
on the Closing Date to the trust account established for the benefit of the Company’s public shareholders, managed pursuant
to that certain Investment Management Trust Agreement to be entered into by and between the Company and Continental Stock Transfer
& Trust Company, as trustee, and into which substantially all of the proceeds of the IPO will be deposited (the “Trust
Account”). For the avoidance of doubt, if the size of the IPO is reduced after the date hereof, this Agreement shall
become null and void and be of no further force and effect.

 

1.4. Delivery of Securities; Forfeiture
of Founder Shares. Upon the Closing Date after delivery of the Purchase Price in accordance with Section 1.3, the Company shall
(ii) issue to the Purchaser, and the Purchaser shall become irrevocably entitled to receive, a unit certificate representing the
Private Units purchased hereunder and a certificate representing the Private Shares, and (ii) cause the forfeiture by the Sponsor
of 136,250 Founder Shares.  In furtherance of the foregoing, the Company shall register the Purchaser as the owner of the
Private Units and the Private Shares in the register of members of the Company and with the Company’s transfer agent by book
entry on or promptly after the Closing Date.

 

1.5 Closing Conditions.

 

(a) The obligation of the Purchaser to purchase
the Private Units at the Closing under this Agreement shall be subject to the fulfillment, at or prior to the Closing of each of
the following conditions, any of which, to the extent permitted by applicable laws, may be waived by the Purchaser:

 

(i) The representations and warranties of the
Company set forth in Section 3 of this Agreement shall have been true and correct as of the date hereof and shall be true and correct
as of the Closing, with the same effect as though such representations and warranties had been made on and as of such date (other
than any such representation or warranty that is made by its terms as of a specified date, which shall be true and correct as of
such specified date), except where the failure to be so true and correct would not have a material adverse effect on the Company
or its ability to consummate the transactions contemplated by this Agreement;

 

    	 	2	 

     

    

 

(ii) The Company shall have performed, satisfied
and complied in all material respects with the covenants, agreements and conditions required by this Agreement to be performed,
satisfied or complied with by the Company or the Sponsor at or prior to the Closing;

 

(iii) No order, writ, judgment, injunction,
decree, determination, or award shall have been entered by or with any governmental, regulatory, or administrative authority or
any court, tribunal, or judicial, or arbitral body, and no other legal restraint or prohibition shall be in effect, preventing
the purchase by the Purchaser of the Securities.

 

(iv) The Company shall have duly executed and
delivered the Underwriting Agreement relating to the IPO.

 

(v) The Sponsor shall have forfeited by surrendering
without consideration to the Company 136,250 Founder Shares.

 

(vi) The Company shall have furnished opinions
of Ellenoff Grossman & Schole LLP, counsel for the Company, and Ogier, British Virgin Islands counsel for the Company, each
addressed to the Purchaser, and dated the Closing Date, and each in form and substance satisfactory to the Purchaser.

 

(b) The obligation of the Company to sell the
Private Units at the Closing under this Agreement shall be subject to the fulfillment, at or prior to the Closing of each of the
following conditions, any of which, to the extent permitted by applicable laws, may be waived by the Company;

 

(i) The representations and warranties of the
Purchaser set forth in Section 2 of this Agreement shall have been true and correct as of the date hereof and shall be true and
correct as of the Closing, with the same effect as though such representations and warranties had been made on and as of such date
(other than any such representation or warranty that is made by its terms as of a specified date, which shall be true and correct
as of such specified date), except where the failure to be so true and correct would not have a material adverse effect on the
Purchaser or its ability to consummate the transactions contemplated by this Agreement;

 

(ii) The Purchaser shall have performed, satisfied
and complied in all material respects with the covenants, agreements and conditions required by this Agreement to be performed,
satisfied or complied with by the Purchaser at or prior to the Closing; and

 

(iii) No order, writ, judgment, injunction,
decree, determination, or award shall have been entered by or with any governmental, regulatory, or administrative authority or
any court, tribunal, or judicial, or arbitral body, and no other legal restraint or prohibition shall be in effect, preventing
the purchase by the Purchaser of the Private Units.

 

2. Representations and Warranties of the
Purchaser

 

The Purchaser represents and warrants to the
Company that:

 

    	 	3	 

     

    

 

2.1. No Government Recommendation or Approval.
It understands that no United States federal or state agency or similar agency of any other country has passed upon or made any
recommendation or endorsement of the Company, the Private Units, the Rights, the Warrants, or Warrant Shares, the Ordinary Shares
underlying the Private Units or the Ordinary Shares issuable upon conversion of the Rights (excluding the Warrant Shares, the “Private
Unit Shares” and, collectively with the Private Units and Warrant Shares, the “Securities”)
or the Private Shares.

 

2.2. Organization.  It is a limited
liability company, validly existing and in good standing under the laws of its jurisdiction and possesses all requisite power and
authority necessary to carry out the transactions contemplated by this Agreement.

 

2.3. Private Offering. It is an “accredited
investor” as such term is defined in Rule 501(a) of Regulation D under the Securities Act of 1933, as amended (the “Securities
Act”). It acknowledges that the sale contemplated hereby is being made in reliance on a private placement exemption
to “accredited investors” within the meaning of Section 501(a) of Regulation D under the Securities Act and similar
exemptions under state law.

 

2.4. Authority. This Agreement has been
validly authorized, executed and delivered by the Purchaser and is a valid and binding agreement enforceable in accordance with
its terms, except as such enforceability may be limited by applicable bankruptcy, insolvency, fraudulent conveyance or similar
laws affecting the enforcement of creditors’ rights generally and subject to general principles of equity (regardless of
whether enforcement is sought in a proceeding at law or in equity).

 

2.5. No Conflicts. The execution, delivery
and performance of this Agreement and the consummation by the Purchaser of the transactions contemplated hereby do not violate,
conflict with or constitute a default under (i)  the Purchaser’s organizational documents, (ii) any agreement,
indenture or instrument to which the Purchaser is a party or (iii) any law, statute, rule or regulation to which the Purchaser
is subject, or any agreement, order, judgment or decree to which the Purchaser is subject.

 

2.6. No Legal Advice from Company. It
acknowledges it has had the opportunity to review this Agreement and the transactions contemplated by this Agreement and the other
agreements entered into between the parties hereto with its own legal counsel and investment and tax advisors. Except for any statements
or representations of the Company made in this Agreement and the other agreements entered into between the parties hereto, it is
relying solely on such counsel and advisors and not on any statements or representations of the Company or any of its representatives
or agents for legal, tax or investment advice with respect to this investment, the transactions contemplated by this Agreement
or the securities laws of any jurisdiction.

 

2.7. Access to Information; Independent
Investigation. Prior to the execution of this Agreement, it has had the opportunity to ask questions of and receive answers
from representatives of the Company concerning an investment in the Company, as well as the finances, operations, business and
prospects of the Company, and the opportunity to obtain additional information to verify the accuracy of all information so obtained.
In determining whether to make this investment, it has relied solely on its own knowledge and understanding of the Company and
its business based upon its own due diligence investigation and the information furnished pursuant to this paragraph. It understands
that no person has been authorized to give any information or to make any representations which were not furnished pursuant to
this Section 2 and it has not relied on any other representations or information in making its investment decision, whether written
or oral, relating to the Company, its operations and/or its prospects.

 

    	 	4	 

     

    

 

2.8. Reliance on Representations and Warranties.
It understands the Private Units are being offered and sold to it in reliance on exemptions from the registration requirements
under the Securities Act, and analogous provisions in the laws and regulations of various states, and that the Company is relying
upon the truth and accuracy of the representations, warranties, agreements, acknowledgments and understandings of the Purchaser
set forth in this Agreement in order to determine the applicability of such provisions.

 

2.9. No Advertisements. It is not subscribing
for the Private Units as a result of or subsequent to any advertisement, article, notice or other communication published in any
newspaper, magazine, or similar media or broadcast over television or radio, or presented at any seminar or meeting.

 

2.10. Legend. It acknowledges and agrees
the certificates (if any) evidencing (i) the Private Units and the Ordinary Shares, the Rights and Warrants underlying the Private
Units and (ii) the Private Shares shall bear a restrictive legend (the “Legend”), in form and substance
as set forth in Section 4.1 hereof, prohibiting the offer, sale, pledge or transfer of the securities, except (1) pursuant
to an effective registration statement covering these securities under the Securities Act or (2) pursuant to any other exemptions
from the registration requirements under the Securities Act and such laws which, in the opinion of counsel for the Company, is
available.

 

2.11. Experience, Financial Capability and
Suitability. It is (i) sophisticated in financial matters and is able to evaluate the risks and benefits of the investment
in the Securities and the Private Shares and (ii) able to bear the economic risk of its investment in the Securities and the Private
Shares for an indefinite period of time because the Securities and the Private Shares have not been registered under the Securities
Act and therefore cannot be sold unless subsequently registered under the Securities Act or an exemption from such registration
is available. It has substantial experience in evaluating and investing in transactions of securities in companies similar to the
Company so that it is capable of evaluating the merits and risks of its investment in the Company and has the capacity to protect
its own interests.  

 

2.12. Investment Purposes. It is acquiring
the Securities and the Private Shares solely for investment purposes, for its own account and not for the account or benefit of
any other person, and not with a view towards the distribution or dissemination thereof and it has no present arrangement to sell
the interest in the Securities or the Private Shares to or through any person or entity.

 

2.13. Restrictions on Transfer. It acknowledges
and understands the Private Units and the Private Shares are being offered in a transaction not involving a public offering in
the United States within the meaning of the Securities Act. The Securities and the Private Shares have not been registered under
the Securities Act, and, if in the future, it decides to offer, resell, pledge or otherwise transfer the Securities or the Private
Shares, such Securities or such Private Shares, as applicable, may be offered, resold, pledged or otherwise transferred only (A) pursuant
to an effective registration statement filed under the Securities Act, (B) pursuant to an exemption from registration under
Rule 144 promulgated under the Securities Act (“Rule 144”), if available, or (C) pursuant to any
other available exemption from the registration requirements of the Securities Act, and in each case in accordance with any applicable
securities laws of any state or any other jurisdiction. It agrees that if any transfer of its Securities or Private Shares or any
interest therein is proposed to be made, as a condition precedent to any such transfer, it may be required to deliver to the Company
an opinion of counsel satisfactory to the Company. Absent registration or another available exemption from registration, it agrees
it will not resell the Securities or the Private Shares. It further acknowledges that because the Company is a shell company, Rule
144 may not be available to it for the resale of the Securities or the Private Shares until the one year anniversary following
consummation of the initial Business Combination (defined below) of the Company, despite technical compliance with the requirements
of Rule 144 and the release or waiver of any contractual transfer restrictions.

 

    	 	5	 

     

    

 

3. Representations and Warranties of the
Company

 

The Company represents and warrants to the
Purchaser that:

 

3.1. Valid Issuance of Share Capital.
The total number of all classes of share capital which the Company has authority to issue is (i) an unlimited number of Ordinary
Shares and (ii) an unlimited number of preferred shares. As of the date hereof, the Company has issued 3,593,750 Ordinary Shares
(of which 468,750 Ordinary Shares are subject to forfeiture as described in the registration statement related to the IPO), and
no preferred shares issued and outstanding. All of the issued share capital of the Company has been duly authorized, validly issued,
and are fully paid and non-assessable.

 

3.2. Title to Securities. Upon issuance
in accordance with, and payment pursuant to, the terms hereof, the warrant agreement to be entered into with a mutually agreeable
warrant agent on or prior to the closing of the IPO (“Warrant Agreement”) and the rights agreement to
be entered into with a mutually agreeable rights agent on or prior to the closing of the IPO (the “Rights Agreement”),
as the case may be, each of the Warrants, the Rights, the Ordinary Shares and the Private Shares will be duly and validly issued,
fully paid and non-assessable, free and clear of any Liens (other than restrictions under applicable securities laws and the restrictions
contained herein). On the date of issuance of the Private Units, the Warrant Shares shall have been reserved for issuance. Upon
issuance in accordance with the terms hereof and the Warrant Agreement, the Purchaser will have or receive good title to the Warrant
Shares, free and clear of any and all Liens (other than restrictions under applicable securities laws and the restrictions contained
herein). Upon issuance in accordance with the terms hereof and the Rights Agreement, the Purchaser will have or receive good title
to the Ordinary Shares issuable upon conversion of the Rights, free and clear of any and all Liens (other than restrictions under
applicable securities laws and the restrictions contained herein).

 

3.3. Organization and Qualification.
The Company has been duly incorporated and is validly existing as a British Virgin Islands business company and has the requisite
corporate power to own its properties and assets and to carry on its business as now being conducted.

 

3.4. Authorization; Enforcement. (i) The
Company has the requisite corporate power and authority to enter into and perform its obligations under this Agreement and to issue
the Securities in accordance with the terms hereof, (ii) the execution, delivery and performance of this Agreement by the
Company and the consummation by it of the transactions contemplated hereby have been duly authorized by all necessary corporate
action and no further consent or authorization of the Company or its Board of Directors or shareholders is required, and (iii) this
Agreement constitutes, and upon the execution and delivery thereof, each of the Rights, the Rights Agreement, the Warrants and
the Warrant Agreement will constitute, valid and binding obligations of the Company enforceable against the Company in accordance
with their respective terms, except as such enforceability may be limited by applicable bankruptcy, insolvency, fraudulent conveyance,
moratorium, reorganization, or similar laws relating to, or affecting generally the enforcement of, creditors’ rights and
remedies or by equitable principles of general application and except as enforcement of rights to indemnity and contribution may
be limited by federal and state securities laws or principles of public policy.

 

    	 	6	 

     

    

 

3.5. No Conflicts. The execution, delivery
and performance of this Agreement and the consummation by the Company of the transactions contemplated hereby do not (i) result
in a violation of the Company’s Memorandum and Articles of Association, (ii) conflict with, or constitute a default
under any agreement, indenture or instrument to which the Company is a party or (iii) conflict with any law statute, rule or regulation
to which the Company is subject or any agreement, order, judgment or decree to which the Company is subject. Other than any federal,
state or foreign securities filings which may be required to be made by the Company subsequent to the Closing, and any registration
statement which may be filed pursuant thereto, the Company is not required under federal, state or local law, rule or regulation
to obtain any consent, authorization or order of, or make any filing or registration with, any court or governmental agency or
self-regulatory entity in order for it to perform any of its obligations under this Agreement or issue (1) the Private Units, the
Rights, the Warrants or the Ordinary Shares underlying the Private Units, the Rights or Warrants or (2) the Private Shares, in
each case, in accordance with the terms hereof.

 

3.6. Operations. As of the date hereof,
the Company has not conducted, and prior to the IPO Closing the Company will not conduct, any operations other than organizational
activities and activities in connection with offerings of the Securities.

 

3.7 Foreign Corrupt Practices. Neither
the Company, nor any director, officer, agent, employee or other Person acting on behalf of the Company has, in the course of its
actions for, or on behalf of, the Company (i) used any corporate funds for any unlawful contribution, gift, entertainment or other
unlawful expenses relating to political activity; (ii) made any direct or indirect unlawful payment to any foreign or domestic
government official or employee from corporate funds; (iii) violated or is in violation of any provision of the U.S. Foreign Corrupt
Practices Act of 1977, as amended; or (iv) made any unlawful bribe, rebate, payoff, influence payment, kickback or other unlawful
payment to any foreign or domestic government official or employee.

 

3.8 Compliance with Anti-Money Laundering
Laws. The operations of the Company are and have been conducted at all times in compliance with applicable financial recordkeeping
and reporting requirements and all other applicable U.S. and non-U.S. anti-money laundering laws and regulations, including, but
not limited to, those of the Currency and Foreign Transactions Reporting Act of 1970, as amended, the USA Patriot Act of 2001 and
the applicable money laundering statutes of all applicable jurisdictions, the rules and regulations thereunder and any related
or similar rules, regulations or guidelines, issued, administered or enforced by any governmental agency (collectively, the “Anti-Money
Laundering Laws”), and no action, suit or proceeding by or before any court or governmental agency, authority or
body or any arbitrator involving the Company with respect to the Anti-Money Laundering Laws is pending or, to the knowledge of
the Company, threatened.

 

3.9 Absence of Litigation. There is
no action, suit, proceeding, inquiry or investigation before or by any court, public board, government agency, self-regulatory
organization or body pending or, to the knowledge of the Company, threatened against or affecting the Company or any of the Company’s
officers or directors, whether of a civil or criminal nature or otherwise, in their capacities as such.

 

3.10 Choice of Law. The Company has
the power to submit, legally, validly, effectively and irrevocably, to the jurisdiction of any state courts in the State of New
York or the United States District Court for the Southern District of New York.

 

4. Legends

 

4.1. Legend. The Company will issue
(i) the Private Units, the Rights, the Warrants and the Private Unit Shares, and when issued, the Warrant Shares and the Ordinary
Shares issuable upon conversion of the Rights, purchased by the Purchaser, and (ii) the Private Shares, in each case, in the name
of the Purchaser. Each register and book entry for each of the Securities and the Private Shares shall contain a notation, and
each certificate (if any) evidencing the Securities and the Private Shares shall be stamped or otherwise imprinted with a legend,
in substantially the following form

 

    	 	7	 

     

    

 

THESE SECURITIES (i) HAVE NOT BEEN
REGISTERED UNDER THE UNITED STATES SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), AND THESE SECURITIES
MAY NOT BE OFFERED, SOLD, PLEDGED OR OTHERWISE TRANSFERRED EXCEPT (A) PURSUANT TO AN EFFECTIVE REGISTRATION STATEMENT FILED UNDER
THE SECURITIES ACT, (B) PURSUANT TO AN EXEMPTION FROM REGISTRATION PROVIDED BY RULE 144 UNDER THE SECURITIES ACT (IF AVAILABLE)
OR (C) PURSUANT TO ANY OTHER EXEMPTION FROM THE REGISTRATION REQUIREMENTS OF THE SECURITIES ACT, IN EACH CASE IN ACCORDANCE WITH
ANY APPLICABLE SECURITIES LAWS OF ANY STATE OF THE UNITED STATES OR ANY OTHER JURISDICTION. HEDGING TRANSACTIONS INVOLVING THESE
SECURITIES MAY NOT BE CONDUCTED UNLESS IN COMPLIANCE WITH THE SECURITIES ACT.

 

“THE SECURITIES REPRESENTED
BY THIS CERTIFICATE ARE SUBJECT TO AN AGREEMENT BETWEEN CONSTELLATION ALPHA CAPITAL CORP. AND COWEN INVESTMENTS LLC AND MAY ONLY
BE OFFERED, SOLD, TRANSFERRED, PLEDGED OR OTHERWISE DISPOSED DURING THE TERM OF THE LOCKUP PURSUANT TO THE TERMS SET FORTH THEREIN.”

 

4.2. Purchaser’s Compliance. Nothing
in this Section 4 shall affect in any way the Purchaser’s obligations and agreements to comply with all applicable securities
laws upon resale of the Securities.

 

4.3. Company’s Refusal to Register
Transfer of the Securities and the Private Shares. The Company shall refuse to register any transfer of the Securities or the
Private Shares, if in the reasonable judgment of the Company such purported transfer would not be made (i) pursuant to an
effective registration statement filed under the Securities Act, or (ii) pursuant to an available exemption from the registration
requirements of the Securities Act.

 

4.4. Registration Rights. The Purchaser
will be entitled to certain registration rights which will be governed by a registration rights agreement (“Registration
Rights Agreement”) to be entered into with the Company on or prior to the closing of the IPO; provided, however,
that the Purchaser may not exercise its demand and “piggy back” registration rights pursuant to such Registration Rights
Agreement after five (5) and seven (7) years after the effective date of the Registration Statement, respectively, and the Purchaser
may not exercise its demand registration rights thereunder more than one time.

 

4.5 Removal of Legend. Following the
expiration of the transfer restrictions set forth herein, if any of the Securities or the Private Shares are eligible to be sold
without restriction under, and without the Company being in compliance with the current public information requirements of, Rule
144 under the Securities Act, then at the Purchaser’s request, the Company will cause the Company’s transfer agent
to remove the legend set forth in Section 4.1. In connection therewith, if required by the Company’s transfer agent, the
Company will promptly cause an opinion of counsel to be delivered to and maintained with its transfer agent, together with any
other authorizations, certificates and directions required by the transfer agent that authorize and direct the transfer agent to
issue such Securities without any such legend.

 

    	 	8	 

     

    

 

5. Transfer Restrictions

 

5.1 FINRA Lock-up. The Purchaser acknowledges
and agrees that the Private Units, the Warrants, the Private Unit Shares and the Warrant Shares shall not be transferable, saleable
or assignable until after the consummation of an acquisition, share exchange, purchase of all or substantially all of the assets
of, or any other similar business combination with one or more businesses or entities (a “Business Combination”),
except to permitted transferees. The Private Units, the Rights, the Warrants, the Private Unit Shares, the Warrant Shares, the
Ordinary Shares issuable upon conversion of the Rights, and the Private Shares will be deemed compensation by the Financial Industry
Regulatory Authority (“FINRA”) and will therefore be subject to lock-up for a period of 180 days immediately
following the date of effectiveness of the Registration Statement or commencement of sales of the IPO, subject to certain limited
exceptions, pursuant to Rule 5110(g)(1) of the FINRA Manual. Accordingly, the Private Units, the Rights, the Warrants, the Private
Unit Shares, the Warrant Shares, the Ordinary Shares issuable upon conversion of the Rights, and the Private Shares may not be
sold, transferred, assigned, pledged or hypothecated for 180 days immediately following the effective date of the Registration
Statement except to any underwriter or selected dealer participating in the IPO and the bona fide officers or partners of the Purchaser
and any such participating underwriter or selected dealer nor may they be the subject of any hedging, short sale, derivative, put
or call transaction that would result in the economic disposition of the securities by any person during such 180-day period.

 

5.2 Transfer Restrictions.

 

(i) Subject to Section 5.1, the Purchaser shall
not Transfer (as defined below) any Private Shares until, with respect to 50% of the Private Shares, the earlier of (1) one year
after the consummation of a Business Combination or earlier if, subsequent to such Business Combination, and (2) the date on which
the closing sale price of the Ordinary Shares equals or exceeds $12.50 per share (as adjusted for stock splits, stock dividends,
reorganizations, recapitalizations and the like) for any 20 trading days within any 30-trading day period commencing after such
Business Combination and, with respect to the remaining 50% of the Private Shares, upon one year after the consummation of a Business
Combination or earlier if, subsequent to such Business Combination, the Company consummates a subsequent liquidation, merger, stock
exchange or other similar transaction that results in all of the Company’s shareholders having the right to exchange their
Ordinary Shares for cash, securities or other property. For purposes of this Agreement, “Transfer” shall
mean the (x) sale of, offer to sell, contract or agreement to sell, hypothecate, pledge, grant of any option to purchase or otherwise
dispose of or agreement to dispose of, directly or indirectly, or establishment or increase of a put equivalent position or liquidation
with respect to or decrease of a call equivalent position within the meaning of Section 16 of the Securities Exchange Act of 1934,
as amended, and the rules and regulations of the Securities and Exchange Commission (the “Commission”)
promulgated thereunder with respect to, any security, (y) entry into any swap or other arrangement that transfers to another, in
whole or in part, any of the economic consequences of ownership of any security, whether any such transaction is to be settled
by delivery of such securities, in cash or otherwise, or (z) public announcement of any intention to effect any transaction specified
in clause (x) or (y).

 

(iii) Notwithstanding the provisions set forth
in paragraph 5.2(i), Transfers of the Private Shares and any Securities are permitted to (a) to any members of the Purchaser or
any affiliates of the Purchaser or any of its members; (b) by private sales or transfers made in connection with the consummation
of a Business Combination at prices no greater than the price at which the securities were originally purchased; (c) in the event
of the Company’s liquidation prior to the completion of a Business Combination; or (d) by virtue of the laws of the State
of Delaware or the Purchaser’s limited liability company agreement upon dissolution of the Purchaser; provided, however,
that in the case of clauses (a) through (c), these permitted transferees must enter into a written agreement agreeing to be bound
by the transfer restrictions described herein.

 

    	 	9	 

     

    

 

6. Securities Laws Restrictions

 

The Purchaser agrees not to sell, transfer,
pledge, hypothecate or otherwise dispose of all or any part of the Securities unless, prior thereto (a) a registration statement
on the appropriate form under the Securities Act and applicable state securities laws with respect to the Securities proposed to
be transferred shall then be effective or (b) the Company shall have received an opinion from counsel reasonably satisfactory
to the Company, that such registration is not required because such transaction complies with the Securities Act and the rules
promulgated by the Commission thereunder and with all applicable state securities laws.

 

7. Partial Forfeiture in Connection with
Business Combination Closing

 

If, in connection with the closing of the Business
Combination, the Sponsor agrees to forfeit any Founder Shares and/or Founder Units to the Company at no cost or subject its Founder
Shares and/or Founder Units to contractual terms or restrictions, convert its Founder Shares and/or Founder Units (including the
Ordinary Shares and Warrants comprising such Founder Units) into other securities or contractual rights or otherwise modify the
terms of its Founder Shares and/or Founder Units, then, provided that the Sponsor is not being issued any other equity or equity-related
securities in the Business Combination not also being issued to the Purchaser on a pro rata basis, the Purchaser agrees to forfeit,
subject, convert or modify its Private Shares and/or Private Units, as applicable, on a pro rata basis and on the same terms as
the Sponsor and any other holders of Founder Shares and/or Founder Units. Any forfeiture under this Agreement shall take effect
as a surrender for no consideration as a matter of British Virgin Islands law.

 

8. Waiver of Distributions from Trust Account

 

In connection with the Securities and the Private
Shares acquired pursuant to this Agreement, the Purchaser hereby waives any and all right, title, interest or claim of any kind
in or to any distributions from the Trust Account.

 

9. Rescission Right Waiver

 

9.1. Rescission Waiver. The Purchaser
understands and acknowledges that an exemption from the registration requirements of the Securities Act requires there be no general
solicitation of purchasers of the Private Units or the Private Shares. In this regard, if the Offering were deemed to be a general
solicitation with respect to the Private Units, the offer and sale of such Private Units may not be exempt from registration and,
if not, the Purchaser may have a right to rescind its purchase of the Private Units. In order to facilitate the completion of the
Offering and in order to protect the Company, its shareholders and the Trust Account from claims that may adversely affect the
Company or the interests of its shareholders, the Purchaser hereby agrees to waive, to the maximum extent permitted by applicable
law, any claims, right to sue or rights in law or arbitration, as the case may be, to seek rescission of its purchase of the Private
Units as a result of the issuance of the Private Units being deemed to be in violation of Section 5 of the Securities Act. The
Purchaser acknowledges and agrees this waiver is being made in order to induce the Company to sell the Private Units to the Purchaser.
The Purchaser agrees the foregoing waiver of rescission rights shall apply to any and all known or unknown actions, causes of action,
suits, claims or proceedings (collectively, “Claims”) and related losses, costs, penalties, fees, liabilities
and damages, whether compensatory, consequential or exemplary, and expenses in connection therewith, including reasonable attorneys’
and expert witness fees and disbursements and all other expenses reasonably incurred in investigating, preparing or defending against
any Claims, whether pending or threatened, in connection with any present or future actual or asserted right to rescind the purchase
of the Units hereunder or relating to the purchase of the Private Units and the transactions contemplated hereby.

 

    	 	10	 

     

    

 

9.2. No Recourse Against Trust Account.
The Purchaser agrees not to seek recourse against the Trust Account for any reason whatsoever in connection with its acquisition
of the Private Units or the Private Shares or any Claim that may arise now or in the future.

 

9.3. Section 8 Waiver. The Purchaser
agrees that to the extent any waiver of rights under this Section 9 is ineffective as a matter of law, the Purchaser has offered
such waiver for the benefit of the Company as an equitable right that shall survive any statutory disqualification or bar that
applies to a legal right. The Purchaser acknowledges the receipt and sufficiency of consideration received from the Company hereunder
in this regard.

 

10. Terms of the Private Units and Private
Shares; Voting

 

10.1 Terms of the Private Units and Private
Shares. The Private Units shall be substantially identical to the Public Units, except the Private Units: (i) will be subject
to the transfer restrictions described herein; (ii) are being purchased pursuant to an exemption from the registration requirements
of the Securities Act and will become freely tradable only after certain conditions are met or the resale of the Private Units
is registered under the Securities Act; and (iii) the Warrants underlying the Private Units are not redeemable by the Company,
provided the Private Units are held by the Purchaser or its permitted transferees. The Private Shares shall be identical to the
Founder Shares, and the Private Shares shall be identical to the Ordinary Shares comprising the Public Units, except that the Private
Shares: (i) will be subject to the transfer restrictions described herein; (ii) are being purchased pursuant to an exemption from
the registration requirements of the Securities Act and will become freely tradable only after certain conditions are met or the
resale of the Private Units is registered under the Securities Act.

 

10.2 Voting. The Purchaser agrees that
if the Company seeks shareholder approval of a proposed Business Combination, then in connection with such proposed Business Combination,
the Purchaser shall vote the Private Shares and any other Ordinary Shares owned by it in favor of such proposed Business Combination.
The Purchaser agrees: (i) not to propose an amendment to the Company’s Memorandum and Articles of Association with respect
to its pre-Business Combination activities prior to the consummation of such a Business Combination unless the Company provides
dissenting public shareholders with the opportunity to redeem their Ordinary Shares in conjunction with any such amendment; and
(ii) not to redeem any Ordinary Shares owned by it (including the Private Shares) into the right to receive cash from the Trust
Account in connection with a shareholder vote to approve the Company’s proposed initial Business Combination (or to sell
any Ordinary Shares in a tender offer in connection with a proposed Business Combination if the Company does not seek shareholder
approval in connection therewith) or a vote to amend the provisions of the Company’s Memorandum and Articles of Association
relating to shareholders’ rights or pre-Business Combination activity.

 

11. Governing Law; Jurisdiction; Waiver
of Jury Trial

 

11.1 Governing Law. This Agreement,
the entire relationship of the parties hereto, and any litigation between the parties (whether grounded in contract, tort, statute,
law or equity) shall be governed by, construed in accordance with, and interpreted pursuant to the laws of the State of New York,
including, without limitation, Sections 5-1401 and 5-1402 of the New York General Obligations Law and New York Civil Practice Laws
and Rules 327(b).

 

    	 	11	 

     

    

 

11.2 Jurisdiction. The parties (i) hereby
irrevocably and unconditionally submit to the jurisdiction of the state courts of New York and to the jurisdiction of the United
States District Court for the Southern District of New York for the purpose of any suit, action or other proceeding arising out
of or based upon this Agreement, (b) agree not to commence any suit, action or other proceeding arising out of or based upon this
Agreement except in state courts of New York or the United States District Court for the Southern District of New York, and (c)
hereby waive, and agree not to assert, by way of motion, as a defense, or otherwise, in any such suit, action or proceeding, any
claim that it is not subject personally to the jurisdiction of the above-named courts, that its property is exempt or immune from
attachment or execution, that the suit, action or proceeding is brought in an inconvenient forum, that the venue of the suit, action
or proceeding is improper or that this Agreement or the subject matter hereof may not be enforced in or by such court.

 

11.3 Waiver of Jury Trial. The parties
hereto hereby waive any right to a jury trial in connection with any litigation pursuant to this agreement and the transactions
contemplated hereby.

 

12. Assignment; Entire Agreement; Amendment

 

12.1. Assignment. Neither this Agreement
nor any rights hereunder may be assigned by any party to any other person other than by the Purchaser, without the prior consent
of the Company, to one or more persons agreeing to be bound by the terms hereof. Upon such assignment by a Purchaser, the assignee(s)
shall become Purchaser hereunder and have the rights and obligations provided for herein to the extent of such assignment.

 

12.2. Entire Agreement. This Agreement,
together with any documents, instruments and writings that are delivered pursuant hereto or referenced herein, constitutes the
entire agreement and understanding between the parties as to the subject matter hereof and supersedes any and all prior discussions,
agreements and understandings of any and every nature.

 

12.3. Amendment. Except as expressly
provided in this Agreement, neither this Agreement nor any term hereof may be amended, waived, discharged or terminated other than
by a written instrument signed by the party against whom enforcement of any such amendment, waiver, discharge or termination is
sought.

 

12.4. Binding upon Successors. This
Agreement shall be binding upon and inure to the benefit of the parties hereto and to their respective heirs, legal representatives,
successors and permitted assigns.

 

13. Notices

 

All notices, requests, consents and other communications
hereunder shall be in writing, shall be addressed to the receiving party’s address set forth herein or to such other address
as a party may designate by notice hereunder, and shall be either (a) delivered by hand, (b) sent by overnight courier, or (c)
sent by certified mail, return receipt requested, postage prepaid. All notices, requests, consents and other communications hereunder
shall be deemed to have been given either (i) if by hand, at the time of the delivery thereof to the receiving party at the address
of such party set forth above, (ii) if sent by overnight courier, on the next business day following the day such notice is delivered
to the courier service, or (iii) if sent by certified mail, on the fifth business day following the day such mailing is made.

 

    	 	12	 

     

    

 

14. Tax Information

 

14.1 Form W-9. The Purchaser has, concurrently
with the execution of this Agreement, executed and delivered the Internal Revenue Service Form W-9 attached hereto as Exhibit
A.

 

14.2 QEF Election Information. As soon
as practicable following the close of each taxable year of the Company, the Company shall determine whether the Company is or was
deemed to be a “passive foreign investment company” (a “PFIC”) within the meaning of U.S.
Internal Revenue Code of 1986, as amended, and the regulations promulgated thereunder (collectively, the “Code”)
for such taxable year. If the Company determines that the Company is or was a PFIC in any year, for the year of determination and
for each year thereafter during which the Purchaser holds an equity interest in the Company, including Warrants, the Company shall
(i) make available to the Purchaser the information that may be required to make or maintain a “qualified electing fund”
election under the Code with respect to the Company and (ii) furnish the information required to be reported under Section 1298(f)
of the Code.

 

15. Counterparts

 

This Agreement may be executed in one or more
counterparts, all of which when taken together shall be considered one and the same agreement and shall become effective when counterparts
have been signed by each party and delivered to the other party, it being understood that both parties need not sign the same counterpart. 
In the event that any signature is delivered by facsimile transmission or any other form of electronic delivery, such signature
shall create a valid and binding obligation of the party executing (or on whose behalf such signature is executed) with the same
force and effect as if such signature page were an original thereof.

 

16. Survival; Severability

 

16.1. Survival. The representations
and warranties of the parties hereto shall survive the Closing until one (1) year following the consummation of an initial Business
Combination.

 

16.2. Severability. In the event that
any provision of this Agreement becomes or is declared by a court of competent jurisdiction to be illegal, unenforceable or void,
this Agreement shall continue in full force and effect without said provision; provided that no such severability shall
be effective if it materially changes the economic benefit of this Agreement to any party.

 

17. Headings

 

The titles and subtitles used in this Agreement
are used for convenience only and are not to be considered in construing or interpreting this Agreement.

 

18. Construction

 

The parties hereto have participated jointly
in the negotiation and drafting of this Agreement. If an ambiguity or question of intent or interpretation arises, this Agreement
will be construed as if drafted jointly by the parties hereto and no presumption or burden of proof will arise favoring or disfavoring
any party hereto because of the authorship of any provision of this Agreement. The words “include,” “includes,”
and “including” will be deemed to be followed by “without limitation.” Pronouns in masculine,
feminine, and neuter genders will be construed to include any other gender, and words in the singular form will be construed to
include the plural and vice versa, unless the context otherwise requires. The words “this Agreement,” “herein,”
“hereof,” “hereby,” “hereunder,” and words of similar import refer to
this Agreement as a whole and not to any particular subdivision unless expressly so limited. The parties hereto intend that each
representation, warranty, and covenant contained herein will have independent significance. If any party hereto has breached any
representation, warranty, or covenant contained herein in any respect, the fact that there exists another representation, warranty
or covenant relating to the same subject matter (regardless of the relative levels of specificity) which such party hereto has
not breached will not detract from or mitigate the fact that such party hereto is in breach of the first representation, warranty,
or covenant. 

 

[REMAINDER OF PAGE INTENTIONALLY LEFT BLANK]

 

    	 	13	 

     

    

 

This subscription is accepted by the Company as of the date first
written above.

 

	 	CONSTELLATION ALPHA CAPITAL CORP.
	 	 	 
	 	By:	 
	 	Name: 	 Rajiv Shukla
	 	Title: 	Chief Executive Officer

 

Accepted and agreed this

____ day of June, 2017

 

COWEN INVESTMENTS LLC

 

	By:	 	 
	Name:	 	 
	Title:    	 	 

 

[Signature Page to Unit Subscription Agreement]

 

     

     

    

 

Exhibit
A

 

FORM W-9

 

[Attached]

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00272-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00272-of-00352.parquet"}]]