Document:

exv10w2

	 	 	 	 	 

Exhibit 10.2

FIRST AMENDMENT TO AMENDED AND RESTATED TEXAS LIMITED

PARTNERSHIP AGREEMENT

OF

HOLLIDAY FENOGLIO FOWLER, L.P.

          This FIRST AMENDMENT TO AMENDED AND RESTATED TEXAS LIMITED PARTNERSHIP AGREEMENT OF HOLLIDAY
FENOGLIO FOWLER, L.P. (this “First Amendment”) is dated as of May 6, 2011 and is effective as of
the date hereof, by and among (a) HOLLIDAY GP CORP., a Delaware corporation (the “General
Partner”), and (b) HFF LP ACQUISITION LLC, a Delaware limited liability company (“Acquisition”),
and HFF PARTNERSHIP HOLDINGS LLC, a Delaware limited liability company (“Holdco” and together with
Acquisition, each a “Limited Partner” and collectively, the “Limited Partners”). The General
Partner and the Limited Partners are each referred to herein as a “Partner” and collectively
referred to herein as the “Partners.” Capitalized terms not otherwise defined herein shall have
the respective meanings ascribed to such terms in the Partnership Agreement (as defined below).

RECITALS

          WHEREAS, on February 5, 2007, the Partners entered into that certain Amended and Restated
Texas Limited Partnership Agreement of Holliday Fenoglio Fowler, L.P. (the “Partnership
Agreement”);

          WHEREAS, the Partners desire to replace the Operating Committee of Holliday Fenoglio Fowler,
L.P. (the “Partnership”) with an Executive Committee and a Leadership Team; and

          WHEREAS, the Partners have agreed to enter into this First Amendment to the Partnership
Agreement to provide for the replacement of the Operating Committee of the Partnership with an
Executive Committee and a Leadership Team.

          NOW, THEREFORE, for good and valuable consideration, the receipt and sufficiency of which are
hereby acknowledged, the parties hereto agree as follows:

AGREEMENT

1. Amendments to the Partnership Agreement. The following amendments are hereby made to
the Partnership Agreement:

	 	(a)	 	Article I is hereby amended by deleting the text “Operating Committee” from
the definition of “Class A Common Stock Equivalent” therein and replacing it with the text
“Executive Committee.”
	 
	 	(b)	 	Article I is hereby further amended by deleting the text of the definition of
“Operating Committee” therein in its entirety.
	 
	 	(c)	 	Article I is hereby further amended by adding the following definitions
thereto:

 

 

“Executive Committee” shall have the meaning set forth in
Section 3.4(a) hereof.

“Leadership Team” shall have the meaning set forth in Section
3.4(a) hereof.

	 	(d)	 	Section 3.3(b) is hereby amended by deleting the text “and ‘Operating
Committee’” from the second line thereof.
	 
	 	(e)	 	Section 3.4 is hereby amended by deleting the text thereof in its entirety
and replacing it with the following text:

Section 3.4. Managing Member, Leadership Team and Executive
Committee.

(a) The Managing Member, the “Leadership Team” and the “Executive
Committee” shall be elected in accordance with the terms set forth
below. The sole rights and responsibilities of the Managing
Member, the Leadership Team and the Executive Committee hereunder
shall be to (i) participate in the process of preparing the
proposed Annual Operating Budget in accordance with and subject to
the provisions of Section 3.5 and (ii) consult with and make
non-binding recommendations to the General Partner in connection
with the General Partner’s performance of its duties and
obligations (and the exercise of its rights) hereunder.

(b) (i) The Managing Member shall be a Voting Right Holder, shall
be elected by Super Majority Vote and shall serve a term of two
(2) years, after which the Managing Member and any other Voting
Right Holder may stand for election or re-election, as the case
may be, by Super Majority Vote; (ii) the initial Managing Member
shall be John H. Pelusi, Jr.; and (iii) the Managing Member may be
removed by a vote of 75% or more of the Voting Interests (and in
any such event the replacement Managing Member shall subject to
the terms hereof serve the then remaining term of such removed
Managing Member).

(c) The Leadership Team shall
initially be comprised of (i)
each office head, line of business head or specialty head of the
Partnership and (ii) each member of the Executive Committee. The members of the Leadership
Team shall serve a term of one (1) year, after which each member of the Leadership Team may elect to stand for
re-appointment by majority vote of the Executive Committee members; provided that if such Leadership Team member
elects not to serve for re-appointment, or if the Executive Committee determines that such
Leadership Team member should not serve an additional term, the Executive Committee
may appoint any other qualified employee of the Partnership to serve on the Leadership Team.
The Executive Committee may by majority vote expand or reduce the size of the Leadership Team upon any increase or
decrease, respectively, in the number, size or scope of offices, lines of business or specialties of the Partnership.

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(c) The Executive Committee shall at all times be comprised of at
least three (3) but not more than seven (7) voting members and
may at any time include up to two (2) non-voting members, as each
such number shall be determined by a majority vote of the
non-Executive Committee members of the Leadership Team. The
members of the Executive Committee shall be elected by a majority
vote of the non-Executive Committee members of the Leadership Team
to serve a term of two (2) years, after which each member of the
Executive Committee and any other qualified employee of the
Partnership may stand for re-election or election, as the case may
be, by majority vote of the non-Executive Committee members of the
Leadership Team. The initial Executive Committee shall be
comprised of three voting members, who are: John H. Pelusi, Jr.,
Mark D. Gibson and Joe B. Thornton, Jr., one ad hoc member, John
P. Fowler (who shall be a non-voting member), and two non-voting
members, who are: Gregory R. Conley and Nancy O. Goodson. Any
member of the Executive Committee is subject to removal prior to
the end of his or her term by a recall majority vote of the
non-Executive Committee members of the Leadership Team and, if
such removal is voted, the non-Executive Committee members of the
Leadership Team shall vote to replace such Executive Committee
member by majority vote (and in such event the replacement
Executive Committee member shall (subject to the terms hereof)
serve the remaining term of the Executive Committee member so
recalled).

	 	(f)	 	Section 3.5 is hereby amended by deleting the text thereof in its entirety
and replacing it with the following text:

Section 3.5. Budget. The annual operating budget of the
Partnership and its Subsidiaries, if any, (the “Annual Operating
Budget”) shall be prepared by the Managing Member (or his
designee) by December 1st of each year for approval by
the Executive Committee in consultation with the Leadership Team.
The Annual Operating Budget shall be based on, inter
alia, information provided to the Managing Member by the
heads of each office and line of business of the Partnership and
its Subsidiaries, if any, and shall set forth in reasonable detail
budgeted monthly operating income and monthly operating capital
and other

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expenses for the Partnership and its Subsidiaries, if any
(including, without limitation, estimated bonuses for each office
and line of business). Upon approval by the Executive Committee
in consultation with the Leadership Team, the same shall be
submitted to the Voting Right Holders for approval by a Super
Majority Vote. If the Voting Right Holders fail to approve the
Annual Operating Budget by Super Majority Vote, the same will be
revised and resubmitted for approval as set forth above; this
process will be followed until an Annual Operating Budget is
approved by the Voting Right Holders as set forth above. Upon
such approval, the Annual Operating Budget will then be submitted
as a non-binding recommendation to the General Partner. The
General Partner may revise in any and all respects the process by
which the Annual Operating Budget is prepared at any time and from
time to time in its sole discretion. The duly authorized officers
of the Partnership shall have the right to incur expenses and make
expenditures in accordance with the terms of the approved Annual
Operating Budget.

2. Governing Law. THIS FIRST AMENDMENT SHALL BE GOVERNED BY AND CONSTRUED AND ENFORCED IN
ACCORDANCE WITH THE LAWS OF THE STATE OF TEXAS, INCLUDING BOTH MATTERS OF INTERNAL LAW AND CONFLICT
OF LAWS.

3. Severability. If this First Amendment or any portion thereof is, or the operations
contemplated hereby are, found to be inconsistent with or contrary to any valid applicable laws or
official orders, rules and regulations, the inconsistent or contrary provisions of this First
Amendment shall be null and void and such laws, orders, rules and regulations shall control and, as
so modified, shall continue in full force and effect; provided, however, that nothing herein
contained shall be construed as a waiver of any right to question or contest any such Law, order,
rule or regulation in any forum having jurisdiction.

4. Effectiveness. This First Amendment shall be made effective as of the date hereof and
binding on all Partners. Except as expressly provided herein, all other terms and provisions of
the Partnership Agreement shall remain in full force and effect.

5. Counterparts. This First Amendment may be executed in a number of counterparts, each of
which shall be deemed an original and all of which shall constitute one and the same First
Amendment.

[Signature Page Follows]

4

 

John H. Pelusi

          IN WITNESS WHEREOF, the parties hereto have caused this First Amendment to be duly executed
and delivered as of the day and year first above written.

	 	 	 	 	 
	 	GENERAL PARTNER:

HOLLIDAY GP CORP., a Delaware corporation

 	 
	 	By:  	/s/
John H. Pelusi, Jr.	 
	 	 	Name:  	John H. Pelusi, Jr. 	 
	 	 	Title:  	President 	 
	 
	 	LIMITED PARTNERS:

HFF LP ACQUISITION LLC, a Delaware limited liability company

 	 
	 	By:  	HFF Holdings LLC, a Delaware limited liability company, its sole Member
 	 
	 	 	 	 
	 	By:  	/s/
John H. Pelusi, Jr.	 
	 	 	Name:  	John H. Pelusi, Jr. 	 
	 	 	Title:  	Managing Member 	 
	 
	 	HFF PARTNERSHIP HOLDINGS LLC, a Delaware limited liability company

 	 
	 	By:  	HFF Inc., a Delaware corporation, its sole Member
 	 
	 	 	 	 
	 	By:  	/s/
John H. Pelusi, Jr.	 
	 	 	Name:  	John H. Pelusi, Jr. 	 
	 	 	Title:  	Chief Executive Officer 	 
	 

5exv4w3

Exhibit 4.3

INDENTURE

dated as of March 9, 2011

by and between

JPR ROYALTY SUB LLC,

a Delaware limited liability company,

as issuer of the Notes described herein,

and

U.S. BANK NATIONAL ASSOCIATION,

a national banking association,

as initial trustee of the Notes described herein

 

 

Table of Contents

	 	 	 	 	 
	 	 	Page	 
	GRANTING CLAUSE
	 	 	1	 
	HABENDUM CLAUSE
	 	 	2	 
	 
	ARTICLE I 

GENERAL	 	 	 	 
	 
	Section 1.1 Rules of Construction and Defined Terms
	 	 	3	 
	Section 1.2 Compliance Certificates and Opinions
	 	 	3	 
	Section 1.3 Acts of Noteholders
	 	 	4	 
	 
	ARTICLE II 

THE NOTES	 	 	 	 
	 
	Section 2.1 Amount of Notes; Terms; Form; Execution and Delivery
	 	 	5	 
	Section 2.2 Restrictive Legends
	 	 	8	 
	Section 2.3 Registrar, Paying Agent and Calculation Agent
	 	 	11	 
	Section 2.4 Paying Agent to Hold Money in Trust
	 	 	12	 
	Section 2.5 Method of Payment
	 	 	13	 
	Section 2.6 Minimum Denominations
	 	 	15	 
	Section 2.7 Transfer and Exchange; Cancellation
	 	 	15	 
	Section 2.8 Mutilated, Destroyed, Lost or Stolen Notes
	 	 	16	 
	Section 2.9 Payments of Transfer Taxes
	 	 	17	 
	Section 2.10 Book-Entry Provisions
	 	 	17	 
	Section 2.11 Special Transfer Provisions
	 	 	19	 
	Section 2.12 Temporary Definitive Notes
	 	 	23	 
	Section 2.13 Statements to Noteholders
	 	 	23	 
	Section 2.14 Identification Numbers
	 	 	25	 
	Section 2.15 Refinancing Notes
	 	 	25	 
	Section 2.16 Subordinated Notes
	 	 	27	 
	Section 2.17 Limitation on Number of Holders of Notes
	 	 	28	 
	 
	ARTICLE III 

ACCOUNTS; PRIORITY OF PAYMENTS	 	 	 	 
	 
	Section 3.1 Establishment of Accounts
	 	 	29	 
	Section 3.2 Investments of Cash
	 	 	31	 
	Section 3.3 Payments and Transfers in connection with Issuance of Notes
	 	 	32	 
	Section 3.4 Seller Payments
	 	 	33	 
	Section 3.5 Calculation Date Calculations
	 	 	33	 
	Section 3.6 Payment Date First Step Transfers
	 	 	35	 
	Section 3.7 Payment Date Second Step Withdrawals
	 	 	35	 

i

 

	 	 	 	 	 
	 	 	Page	 
	Section 3.8 Interest Reserve Account and Capital Account; Interest Shortfalls
	 	 	37	 
	Section 3.9 Redemptions
	 	 	38	 
	Section 3.10 Procedure for Redemptions
	 	 	39	 
	Section 3.11 Seller Shortfall
	 	 	40	 
	Section 3.12 Currency Exchange
	 	 	41	 
	 
	ARTICLE IV 

DEFAULT AND REMEDIES	 	 	 	 
	 
	Section 4.1 Events of Default
	 	 	42	 
	Section 4.2 Acceleration, Rescission and Annulment
	 	 	44	 
	Section 4.3 Other Remedies
	 	 	45	 
	Section 4.4 Limitation on Suits
	 	 	46	 
	Section 4.5 Waiver of Existing Defaults
	 	 	47	 
	Section 4.6 Restoration of Rights and Remedies
	 	 	47	 
	Section 4.7 Remedies Cumulative
	 	 	47	 
	Section 4.8 Authority of Courts Not Required
	 	 	48	 
	Section 4.9 Rights of Noteholders to Receive Payment
	 	 	48	 
	Section 4.10 Trustee May File Proofs of Claim
	 	 	48	 
	Section 4.11 Undertaking for Costs
	 	 	48	 
	Section 4.12 Control by Noteholders
	 	 	48	 
	Section 4.13 Senior Trustee
	 	 	49	 
	Section 4.14 Application of Proceeds
	 	 	49	 
	Section 4.15 Waivers of Rights Inhibiting Enforcement
	 	 	49	 
	Section 4.16 Security Interest Absolute
	 	 	49	 
	 
	ARTICLE V 

REPRESENTATIONS, WARRANTIES AND COVENANTS	 	 	 	 
	 
	Section 5.1 Representations and Warranties
	 	 	50	 
	Section 5.2 Covenants
	 	 	54	 
	Section 5.3 Reports and Other Deliverables by the Issuer
	 	 	61	 
	 
	ARTICLE VI 

THE TRUSTEE	 	 	 	 
	 
	Section 6.1 Acceptance of Trusts and Duties
	 	 	61	 
	Section 6.2 Copies of Documents and Other Notices
	 	 	62	 
	Section 6.3 Representations and Warranties
	 	 	62	 
	Section 6.4 Reliance; Agents; Advice of Counsel
	 	 	63	 
	Section 6.5 Not Acting in Individual Capacity
	 	 	65	 
	Section 6.6 Compensation of Trustee
	 	 	65	 
	Section 6.7 Notice of Defaults
	 	 	66	 
	Section 6.8 May Hold Notes
	 	 	66	 
	Section 6.9 Corporate Trustee Required; Eligibility
	 	 	66	 
	Section 6.10 Reports by the Trustee
	 	 	66	 
	Section 6.11 Pledge and Security Agreement and Other Deal Documents
	 	 	66	 
	Section 6.12 Custody of the Collateral
	 	 	67	 
	Section 6.13 Preservation and Disclosure of Noteholder Lists
	 	 	67	 

ii

 

	 	 	 	 	 
	 	 	Page	 
	Section 6.14 Audit Rights
	 	 	68	 
	Section 6.15 Compliance with Applicable Anti-Terrorism and Anti-Money
Laundering Regulations
	 	 	68	 
	Section 6.16 Jurisdiction of Trustee
	 	 	69	 
	Section 6.17 Notice of Event of Default to the Equityholders
	 	 	69	 
	 
	ARTICLE 

VII SUCCESSOR TRUSTEES, REGISTRARS, PAYING AGENTS AND CALCULATION AGENTS	 	 	 	 
	 
	Section 7.1 Resignation and Removal of Trustee, Registrar, Paying Agent
or Calculation Agent
	 	 	69	 
	Section 7.2 Appointment of Successor
	 	 	70	 
	 
	ARTICLE VIII 

INDEMNITY	 	 	 	 
	 
	Section 8.1 Indemnity
	 	 	71	 
	Section 8.2 Noteholders’ Indemnity
	 	 	72	 
	Section 8.3 Survival
	 	 	72	 
	 
	ARTICLE IX 

MODIFICATION	 	 	 	 
	 
	Section 9.1 Modification with Consent of Noteholders
	 	 	72	 
	Section 9.2 Modification Without Consent of Noteholders
	 	 	73	 
	Section 9.3 Subordination; Priority of Payments
	 	 	74	 
	Section 9.4 Execution of Amendments by Trustee
	 	 	74	 
	 
	ARTICLE X 

SUBORDINATION	 	 	 	 
	 
	Section 10.1 Subordination of the Notes
	 	 	75	 
	 
	ARTICLE XI 

DISCHARGE OF INDENTURE	 	 	 	 
	 
	Section 11.1 Discharge of Indenture
	 	 	76	 
	Section 11.2 Release of Security Interest in Certain Cash Collateral
	 	 	77	 
	 
	ARTICLE XII 

MISCELLANEOUS	 	 	 	 
	 
	Section 12.1 Right of Trustee to Perform
	 	 	77	 
	Section 12.2 Waiver
	 	 	77	 
	Section 12.3 Severability
	 	 	77	 
	Section 12.4 Restrictions on Exercise of Certain Rights
	 	 	78	 
	Section 12.5 Notices
	 	 	78	 
	Section 12.6 Assignments
	 	 	79	 
	Section 12.7 Application to Court
	 	 	79	 
	Section 12.8 GOVERNING LAW
	 	 	79	 

iii

 

	 	 	 	 	 
	 	 	Page
	Section 12.9 Jurisdiction

	 	 	79	 
	Section 12.10 Counterparts

	 	 	81	 
	Section 12.11 Table of Contents and Headings

	 	 	81	 
	Section 12.12 Trust Indenture Act

	 	 	81	 
	Section 12.13 Confidential Information

	 	 	81	 
	Section 12.14 Limited Recourse

	 	 	82	 
	Section 12.15 Tax Matters

	 	 	83	 
	Section 12.16 Waiver

	 	 	84	 
	Section 12.17 Distribution Reports

	 	 	84	 

	 	 	 

	Annex A

	 	Rules of Construction and Defined Terms
	Exhibit A

	 	Form of Original Class A Notes
	Exhibit B

	 	Form of Confidentiality Agreement
	Exhibit C

	 	Agents for Service of Process
	Exhibit D

	 	Coverage of Distribution Report
	Exhibit E

	 	UCC Financing Statements
	Exhibit F

	 	Form of Certificate of Euroclear or Clearstream for Permanent Regulation S Global Note
	Exhibit G

	 	Form of Certification of Beneficial Owner of Temporary Regulation S Global Note
	Exhibit H

	 	Form of Certification of Euroclear or Clearstream for Payments
	Exhibit I

	 	Form of Certificate of Proposed Transferor
	Exhibit J

	 	Form of Certificate of Certain Proposed Institutional Accredited Investor Transferees
	Exhibit K

	 	Form of Portfolio Interest Certificate

iv

 

INDENTURE

     This INDENTURE, dated as of March 9, 2011, is by and between JPR ROYALTY SUB LLC, a Delaware
limited liability company, as issuer of the Notes described herein, and U.S. BANK NATIONAL
ASSOCIATION, a national banking association, as initial trustee of the Notes described herein.

GRANTING CLAUSE

     NOW, THEREFORE, THIS INDENTURE WITNESSETH, that, in consideration of the premises and the
acceptance by the Trustee of the trusts hereby created and of the purchase and acceptance of the
Notes by the Noteholders, and for other good and valuable consideration, the receipt of which is
hereby acknowledged, in order to secure (i) the prompt payment of the principal of, Premium (if
any) and interest on, and all other amounts due with respect to, the Notes from time to time
Outstanding hereunder, (ii) the payment of any fees, expenses or other amounts that the Issuer is
obligated to pay under or in respect of the Notes, this Indenture or any other Transaction Document
to which the Issuer is a party, (iii) the payment and performance of all the obligations of the
Issuer in respect of any amendment, modification, extension, renewal or refinancing of the Notes
and (iv) the performance and observance by the Issuer of all the agreements, covenants and
provisions expressed or implied herein and in the Notes for the benefit of the Noteholders
(collectively, the “Secured Obligations”) and for the uses and purposes and subject to the
terms and provisions hereof, the Issuer does hereby grant, bargain, sell, assign, transfer, convey,
mortgage, pledge and confirm unto the Trustee, its successors and assigns, for the security and
benefit of the Trustee and the Noteholders from time to time, a security interest in all right,
title and interest of the Issuer in, to and under the following described property, rights and
privileges (such property, rights and privileges, including all other property, rights and
privileges hereafter specifically subjected to the lien of this Indenture or any indenture
supplemental hereto, being the “Collateral” and, collectively, including all other property
hereafter specifically subjected to the lien of this Indenture or any indenture supplemental
hereto, are included within and defined as the “Indenture Estate”):

     (1) the Purchased Assets;

     (2) the Deal Documents and other agreements to which the Issuer is a party, including those
relating to the rights of the Issuer in respect of the sale, transfer, conveyance, assignment,
contribution, grant and servicing of the Purchased Assets;

     (3) (A) all Accounts established under this Indenture at any time (other than the Escrow
Account), (B) all amounts from time to time credited to such Accounts (other than the Escrow
Account), (C) all cash, financial assets and other investment property, instruments, documents,
chattel paper, general intangibles, accounts and other property from time to time credited to such
Accounts (other than the Escrow Account) or representing investments and reinvestments of amounts
credited to such Accounts (other than the Escrow Account) and (D) all interest, principal payments,
dividends and other distributions payable on or with respect to, and all proceeds of, (i) all
property so credited or representing such investments and reinvestments and (ii) such Accounts
(other than the Escrow Account);

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     (4) all of the Issuer’s rents, issues, profits, revenues and other income of the property
subjected or required to be subjected to the lien of this Indenture;

     (5) all other property and assets of the Issuer with respect to which a security interest can
be created under Article 9 of the UCC, including all goods, deposit accounts (other than the Escrow
Account), investment property, financial assets, letter-of-credit rights, supporting obligations,
commercial tort claims, accounts, contract rights, general intangibles and all other cash;

     (6) all rights of the Issuer (contractual and otherwise) constituting, arising under,
connected with or in any way related to any or all of the foregoing property;

     (7) all books, records, ledger cards, files, correspondence, computer programs, tapes, disks
and related data processing software (owned by the Issuer) that at any time evidence or contain
information relating to any of the foregoing property or are otherwise necessary or helpful in the
collection thereof or realization thereupon;

     (8) all documents of title, policies and certificates of insurance, securities, chattel paper
and other documents or instruments evidencing or pertaining to any of the foregoing property of the
Issuer; and

     (9) all proceeds and products of any and all of the foregoing property;

     BUT SUBJECT TO all of the terms and conditions of this Indenture.

HABENDUM CLAUSE

     TO HAVE AND TO HOLD all and singular the aforesaid property unto the Trustee, its successors
and assigns, in trust for the benefit and security of the Noteholders from time to time of each
class of the Notes, without any priority of any one class of Notes over any other class of Notes by
reason of difference in time of issuance or otherwise, except as expressly provided herein, and for
the uses and purposes and subject to the terms and provisions set forth in this Indenture.

     PROVIDED, HOWEVER, that, notwithstanding any of the foregoing provisions or anything to the
contrary herein, so long as no Event of Default shall have occurred and be continuing, the Issuer
shall have the right, to the exclusion of the Trustee and the Noteholders, to exercise in the
Issuer’s name all rights and powers of the Issuer under the Purchase and Sale Agreement and any
other agreement (including any other Deal Documents) to which the Issuer is or may be a party or
third party beneficiary (including the Counterparty License Agreement), except as otherwise set
forth in any such agreement, and SUBJECT TO all of the terms and conditions of this Indenture.

     It is hereby further agreed that any and all property described or referred to in the Granting
Clause that is hereafter acquired by the Issuer shall ipso facto, and without any other conveyance,
assignment or act on the part of the Issuer or the Trustee, become and be subject to the Security
Interest herein granted as fully and completely as though specifically described

2

 

herein, but nothing contained in this paragraph shall be deemed to modify or change the
obligations of the Issuer contained in the foregoing paragraphs.

     The Issuer does hereby ratify and confirm this Indenture and the other Deal Documents to which
it is a party and, subject to the other terms of this Indenture, does hereby agree that it will not
take or omit to take any action, the taking or omission of which might result in an alteration or
impairment of the assignment hereunder or of any of the rights created by any thereof.

     It is expressly agreed that anything herein contained to the contrary notwithstanding, the
Issuer shall remain liable under the Deal Documents and any other contracts and agreements included
in the Collateral to the extent set forth therein and shall remain obligated to perform all of the
duties and obligations of the Issuer thereunder to the same extent as if this Indenture had not
been executed in accordance with and pursuant to the terms and provisions thereof, the exercise by
the Trustee of any of its rights hereunder shall not release the Issuer from any of its duties or
obligations under any such Deal Documents or other contracts or agreements included in the
Collateral, and, prior to the foreclosure of the lien of this Indenture under Section 4.3, the
Trustee and the Noteholders shall have no obligation or liability under any thereof by reason of or
arising out of this Indenture or the assignment hereunder, nor shall the Trustee or the Noteholders
be required or obligated in any manner to perform or fulfill any obligations or duties of the
Issuer under or pursuant to any Deal Document or any other contract or agreement included in the
Collateral or, except as herein expressly provided, to make any payment, make any inquiry as to the
nature or sufficiency of any payment received by it, present or file any claim or take any action
to collect or enforce any claim for payment assigned hereunder or the payment of any amounts that
may have been assigned to it or to which it may be entitled at any time or times; provided,
however, that, in exercising any right of the Issuer under any Deal Document or any other
contract or agreement included in the Collateral, the Trustee and the Noteholders shall be bound
by, and shall comply with, the provisions thereof applicable to the Issuer in respect of the
exercise of such right and the confidentiality provisions set forth therein to the extent permitted
by Applicable Law.

     IT IS HEREBY COVENANTED AND AGREED by and between the parties hereto as follows:

ARTICLE I

GENERAL

     Section 1.1 Rules of Construction and Defined Terms. The rules of construction set forth in
Annex A shall apply to this Indenture and are hereby incorporated by reference into this
Indenture as if set forth fully in this Indenture. Capitalized terms used but not otherwise
defined in this Indenture shall have the respective meanings given to such terms in Annex
A, which is hereby incorporated by reference into this Indenture as if set forth fully in this
Indenture. Not all terms defined in Annex A are used in this Indenture.

     Section 1.2 Compliance Certificates and Opinions. Upon any application or request by the Issuer to the Trustee to take any action under any
provision of this Indenture, the Issuer shall furnish to the Trustee an Officer’s Certificate
stating that, in the opinion of the signer thereof in his or her capacity as such, all conditions
precedent, if any, provided for in this

3

 

Indenture relating to the proposed action have been
complied with, and an Opinion of Counsel stating that, in the opinion of such counsel, all such
conditions precedent, if any, have been complied with, except that, in the case of any such
application or request as to which the furnishing of such documents is specifically required by any
provision of this Indenture relating to such particular application or request, no Officer’s
Certificate or Opinion of Counsel need be furnished.

     Every Officer’s Certificate or Opinion of Counsel with respect to compliance with a condition
or covenant provided for in this Indenture (other than a certificate provided pursuant to Section
5.3) or any indenture supplemental hereto shall include:

          (a) a statement that each individual signing such certificate or opinion has read such
covenant or condition and the definitions in this Indenture relating thereto;

          (b) a brief statement as to the nature and scope of the examination or investigation upon
which the statements or opinions contained in such certificate or opinion are based;

          (c) a statement that, in the opinion of each such individual in his or her capacity as such,
he or she has made such examination or investigation as is necessary to enable him or her to
express an informed opinion as to whether or not such covenant or condition has been complied with;
and

          (d) a statement as to whether, in the opinion of each such individual, such condition or
covenant has been complied with.

     Section 1.3 Acts of Noteholders.

          (a) Any direction, consent, waiver or other action provided by this Indenture in respect of
the Notes of any class to be given or taken by Noteholders may be embodied in and evidenced by one
or more instruments of substantially similar tenor signed by such Noteholders in person or by an
agent or proxy duly appointed in writing, and, except as herein otherwise expressly provided, such
action shall become effective when such instrument or instruments are delivered to the Trustee or
to the Issuer. Such instrument or instruments (and the action embodied therein and evidenced
thereby) are herein sometimes referred to as the “Act” of the Noteholders signing such
instrument or instruments. Proof of execution of any such instrument or of a writing appointing
any such agent shall be sufficient for any purpose under this Indenture and conclusive in favor of
the Trustee or the Issuer, if made in the manner provided in this Section 1.3(a).

          (b) The fact and date of the execution by any Person of any such
instrument or writing may be
proved by the certificate of any notary public or other officer of any jurisdiction authorized to
take acknowledgments of deeds or administer oaths that the Person executing such instrument
acknowledged to him or her the execution thereof, or by an affidavit of a witness to such execution
sworn to before any such notary or such other officer and, where such execution
is by an officer of a corporation or association, trustee of a trust or member of a
partnership, on behalf of such corporation, association, trust or partnership, such certificate or
affidavit shall also constitute sufficient proof of his or her authority. The fact and date of the
execution of any such

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instrument or writing, or the authority of the Person executing the same, may
also be proved in any other reasonable manner that the Trustee deems sufficient.

          (c) In determining whether the Noteholders have given any direction, consent, request, demand,
authorization, notice, waiver or other Act (a “Direction”) under this Indenture, Notes
owned by the Issuer, any Equityholder or any Affiliate of any such Person shall be disregarded and
deemed not to be Outstanding for purposes of any such determination. In determining whether the
Trustee shall be protected in relying upon any such Direction, only Notes that a Responsible
Officer of the Trustee actually knows to be so owned shall be so disregarded. Notwithstanding the
foregoing, if any such Person owns 100% of the Notes of any class Outstanding, such Notes shall not
be so disregarded as aforesaid.

          (d) Notwithstanding the definition of “Record Date”, the Issuer may, at its option, by
delivery of Officer’s Certificate(s) to the Trustee, set a record date other than the Record Date
to determine the Noteholders in respect of the Notes of any class entitled to give any Direction in
respect of such Notes. Such record date shall be the record date specified in such Officer’s
Certificate, which shall be a date not more than 30 days prior to the first solicitation of
Noteholders in connection therewith. If such a record date is fixed, such Direction may be given
before or after such record date, but only the Noteholders of the applicable class at the close of
business on such record date shall be deemed to be Noteholders for the purposes of determining
whether Noteholders of the requisite proportion of Outstanding Notes of such class have authorized,
agreed or consented to such Direction, and for that purpose the Outstanding Notes of such class
shall be computed as of such record date; provided, that no such Direction by the
Noteholders on such record date shall be deemed effective unless it shall become effective pursuant
to the provisions of this Indenture not later than one year after the record date.

          (e) Any Direction or other action by the Noteholder of any Note shall bind the Noteholder of
every Note issued upon the transfer thereof, in exchange therefor or in lieu thereof, whether or
not notation of such action is made upon such Note, and any Direction or other action by the
Beneficial Holder of any Beneficial Interest in any Note shall bind any transferee of such
Beneficial Interest.

ARTICLE II

THE NOTES

     Section 2.1 Amount of Notes; Terms; Form; Execution and Delivery.

          (a) The Outstanding Principal Balance of any class of Notes that may be authenticated and
delivered from time to time under this Indenture shall not exceed, with respect to the Original
Class A Notes, the initial Outstanding Principal Balance for the Original Class A Notes set forth
in the definition thereof or, with respect to any class (or sub-class) of Subordinated Notes or any
class of Refinancing Notes, the Outstanding Principal Balance authorized in the Resolution and set
forth in an indenture supplemental hereto establishing such Subordinated Notes or Refinancing
Notes; provided, that (i) any Refinancing Notes shall be
issued in accordance with Section 2.15 and (ii) any Subordinated Notes shall be issued in
accordance with Section 2.16.

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          (b) There shall be issued, authenticated and delivered on the Closing Date and on the date of
issuance of any Subordinated Notes or any Refinancing Notes to each of the Noteholders Notes in the
principal amounts and maturities and bearing the interest rates, in each case in registered form
and, in the case of the Original Class A Notes, substantially in the form set forth in Exhibit
A or, in the case of any Subordinated Notes or any Refinancing Notes, substantially in the form
set forth in any indenture supplemental hereto, with such appropriate insertions, omissions,
substitutions and other variations as are required or permitted by this Indenture, and may have
such letters, numbers or other marks of identification and such legends or endorsements
typewritten, printed, lithographed or engraved thereon, as may, consistently herewith, be
prescribed by the Trustee. The Trustee shall authenticate Notes and make Notes available for
delivery only upon the written order of the Issuer signed by a Responsible Officer of the Issuer.
Such order shall specify the aggregate principal amount of Notes to be authenticated, the date of
issue, whether they are to be issued as Global Notes or Definitive Notes and delivery instructions.

     Definitive Notes of each class shall be typewritten, printed, lithographed or engraved or
produced by any combination of these methods, as determined by the Trustee. Any Notes offered and
sold to Institutional Accredited Investors that are not QIBs that are not offered and sold in
offshore transactions in reliance on Regulation S shall be issued initially in the form of
Definitive Notes.

     Any Notes offered and sold to QIBs or sold in reliance on Rule 144A shall be issued initially
in the form of one or more permanent Global Notes in registered form, substantially in the form set
forth in the applicable Exhibit to this Indenture or in any indenture supplemental hereto (each, a
“144A Global Note”), registered in the name of the nominee of DTC, deposited with the
Trustee, as custodian for DTC, duly executed by the Issuer and authenticated by the Trustee as
hereinafter provided. The aggregate principal amount of each 144A Global Note may from time to
time be increased or decreased by adjustments made on the books and records of the Registrar, as
hereinafter provided.

     Any Notes offered and sold to Institutional Accredited Investors in offshore transactions in
reliance on Regulation S shall be issued initially in the form of one or more temporary global
Notes in registered form substantially in the form set forth in the applicable Exhibit to this
Indenture or in any indenture supplemental hereto (each, a “Temporary Regulation S Global
Note”), registered in the name of the nominee of DTC, deposited with the Trustee, as custodian
for DTC, duly executed by the Issuer and authenticated by the Trustee as hereinafter provided. At
any time following the applicable Regulation S Global Note Exchange Date, upon receipt by the
Trustee and the Issuer of a certificate substantially in the form of Exhibit F, executed by
Euroclear or Clearstream, as the case may be, together with copies of certificates from Euroclear
or Clearstream, as the case may be, certifying that it has received certification of non-U.S.
beneficial ownership of a Temporary Regulation S Global Note (or portion thereof) with respect to
any Notes to be exchanged, one or more permanent Global Notes for such Notes in registered form
substantially in the form set forth in the applicable Exhibit to this Indenture or in any indenture
supplemental hereto (each, a “Permanent Regulation S Global Note” and, together with
each Temporary Regulation S Global Note, the “Regulation S Global Notes”) duly
executed by the Issuer and authenticated by the Trustee as hereinafter provided shall be deposited
with the Trustee, as custodian for DTC, and the Registrar shall reflect on its books and records
the date

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and a decrease in the principal amount of the Temporary Regulation S Global Note of such
class in an amount equal to the principal amount of such Temporary Regulation S Global Note
exchanged. Until the Regulation S Global Note Exchange Date with respect to any Temporary
Regulation S Global Note, Beneficial Interests in such Temporary Regulation S Global Note may be
held only through Agent Members acting for and on behalf of Euroclear and Clearstream.

     Notes, if so provided herein or in any indenture supplemental hereto, shall be issued in the
form of permanent certificated Notes in registered form in substantially the form set forth in this
Section 2.1(b) (collectively with any definitive, fully registered Notes issued pursuant to Section
2.5(d) or Section 2.10(b), the “Definitive Notes”).

          (c) Interest shall accrue on any class of Fixed Rate Notes from the date of issuance of such
Fixed Rate Notes and shall be computed for each Interest Accrual Period on the basis of a 360-day
year consisting of twelve 30-day months on the Outstanding Principal Balance of such Notes.
Interest shall accrue on any class of Floating Rate Notes from the date of issuance of such
Floating Rate Notes and shall be computed for each Interest Accrual Period on the basis of a
360-day year and the actual number of days elapsed in such Interest Accrual Period on the
Outstanding Principal Balance of such Notes. If any interest payment is not made when due on a
Payment Date, the unpaid portion of such interest payment will accrue interest at the rate then
applicable to the Notes, compounded annually, until paid in full.

          (d) On the date of any Refinancing, the Issuer shall issue and deliver, as provided in Section
2.15, an aggregate principal amount of Refinancing Notes having the maturities and bearing the
interest rates and such other terms authorized by one or more Resolutions and set forth in any
indenture supplemental hereto providing for the issuance of such Refinancing Notes or specified in
the form of such Refinancing Notes, in each case in accordance with Section 2.15.

          (e) On the date of any Subordinated Note Issuance, the Issuer shall issue and deliver, as
provided in Section 2.16, an aggregate principal amount of Subordinated Notes having the maturities
and bearing the interest rates and such other terms authorized by one or more Resolutions and set
forth in any indenture supplemental hereto providing for the issuance of such Subordinated Notes or
specified in the form of such Subordinated Notes, in each case in accordance with Section 2.16.

          (f) The Notes shall be executed on behalf of the Issuer by the manual or facsimile signature
of a Responsible Officer of the Issuer or any individual authorized to do so by a Responsible
Officer of the Issuer.

          (g) Each Note bearing the manual or facsimile signature of any individual who at the time such
Note was executed was authorized to execute such Note by a Responsible Officer of the Issuer shall
bind the Issuer, notwithstanding that any such individual has ceased to hold such authority
thereafter but prior to the authentication and delivery of such Notes or any payment thereon.

          (h) At any time and from time to time after the execution of any Notes, the Issuer may deliver
such Notes to the Trustee for authentication and, subject to the provisions of

7

 

     Section 2.1(i), the
Trustee shall authenticate such Notes by manual signature upon receipt by it of a written order of
the Issuer. The Notes shall be authenticated on behalf of the Trustee by any Responsible Officer
of the Trustee.

          (i) No Note shall be entitled to any benefit under this Indenture or be valid or obligatory
for any purpose, unless it shall have been executed on behalf of the Issuer as provided in Section
2.1(f) and authenticated by or on behalf of the Trustee as provided in Section 2.1(h). Such
signatures shall be conclusive evidence that such Note has been duly executed and authenticated
under this Indenture. Each Note shall be dated the date of its authentication.

     Section 2.2Restrictive Legends. Each Note (and all Notes issued in exchange therefor or upon
registration of transfer or substitution thereof) shall bear the following legend on the face
thereof (the “Legend”):

THIS NOTE HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE
“SECURITIES ACT”), THE SECURITIES LAWS OF ANY STATE OR THE SECURITIES LAWS OF ANY
OTHER JURISDICTION, NOR IS SUCH REGISTRATION CONTEMPLATED. NEITHER THIS NOTE NOR
ANY INTEREST HEREIN MAY BE ASSIGNED, TRANSFERRED, PLEDGED, ENCUMBERED, SOLD OR
OFFERED FOR SALE OR OTHERWISE DISPOSED OF IN THE ABSENCE OF SUCH REGISTRATION UNDER
THE SECURITIES ACT OR AN EXEMPTION FROM SUCH REGISTRATION THEREUNDER AND ANY OTHER
APPLICABLE SECURITIES LAW REGISTRATION REQUIREMENTS. EACH PERSON WHO ACQUIRES OR
ACCEPTS THIS NOTE OR AN INTEREST HEREIN BY SUCH ACQUISITION OR ACCEPTANCE (1)
REPRESENTS THAT (A) IT IS A QUALIFIED INSTITUTIONAL BUYER (AS DEFINED IN RULE 144A
UNDER THE SECURITIES ACT) AND, IF SUBSEQUENT TO THE INITIAL ACQUISITION HEREOF, IS
PURCHASING THIS NOTE IN A TRANSACTION MEETING THE REQUIREMENTS OF RULE 144A UNDER
THE SECURITIES ACT, (B) IT IS AN INSTITUTIONAL ACCREDITED INVESTOR AS DEFINED IN
SUBPARAGRAPH (a) (1), (2), (3) OR (7) OF RULE 501 UNDER THE SECURITIES ACT (AN
“INSTITUTIONAL ACCREDITED INVESTOR”), HAS SUFFICIENT KNOWLEDGE AND EXPERIENCE IN
FINANCIAL AND BUSINESS MATTERS TO BE CAPABLE OF EVALUATING THE MERITS AND RISKS OF
THE PURCHASE OF THIS NOTE AND IS ABLE AND PREPARED TO BEAR THE ECONOMIC RISK OF
INVESTING IN AND HOLDING THIS NOTE OR (C) IT IS AN INSTITUTIONAL ACCREDITED INVESTOR
THAT IS NOT A U.S. PERSON AND IS ACQUIRING THIS NOTE IN AN OFFSHORE TRANSACTION IN
COMPLIANCE WITH RULE 903 OR 904 OF REGULATION S UNDER THE SECURITIES ACT, (2) AGREES
THAT IT WILL NOT OFFER, SELL OR OTHERWISE TRANSFER THIS NOTE OR AN INTEREST HEREIN,
EXCEPT (A) TO BIOCRYST
PHARMACEUTICALS, INC. (THE “SELLER”), THE ISSUER OR ANY OF THEIR RESPECTIVE
SUBSIDIARIES, (B) FOR SO LONG AS THIS NOTE IS ELIGIBLE FOR RESALE PURSUANT TO RULE
144A UNDER THE

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SECURITIES ACT, TO A PERSON IT REASONABLY BELIEVES IS A QUALIFIED
INSTITUTIONAL BUYER THAT PURCHASES FOR ITS OWN ACCOUNT OR FOR THE ACCOUNT OF A
QUALIFIED INSTITUTIONAL BUYER, TO WHOM NOTICE IS GIVEN THAT THE TRANSFER IS BEING
MADE IN RELIANCE ON RULE 144A UNDER THE SECURITIES ACT OR (C) TO AN INSTITUTIONAL
ACCREDITED INVESTOR THAT IS PURCHASING THIS NOTE OR AN INTEREST HEREIN, AS THE CASE
MAY BE, FOR ITS OWN ACCOUNT OR FOR THE ACCOUNT OF SUCH AN INSTITUTIONAL ACCREDITED
INVESTOR FOR INVESTMENT PURPOSES AND NOT WITH A VIEW TO, OR FOR OFFER OR SALE IN
CONNECTION WITH, ANY DISTRIBUTION IN VIOLATION OF THE SECURITIES ACT AND (3) AGREES
THAT IT WILL GIVE TO EACH PERSON TO WHOM THIS NOTE OR AN INTEREST HEREIN IS
TRANSFERRED A NOTICE SUBSTANTIALLY TO THE EFFECT OF THIS LEGEND; PROVIDED, THAT THE
ISSUER AND THE TRUSTEE SHALL HAVE THE RIGHT PRIOR TO ANY SUCH OFFER, SALE OR
TRANSFER PURSUANT TO CLAUSE (2)(C) OF THIS PARAGRAPH TO REQUIRE THE DELIVERY OF AN
OPINION OF COUNSEL, CERTIFICATION AND/OR OTHER INFORMATION SATISFACTORY TO EACH OF
THEM. THE TERMS “OFFSHORE TRANSACTION” AND “U.S. PERSON” HAVE THE RESPECTIVE
MEANINGS GIVEN TO THEM BY REGULATION S UNDER THE SECURITIES ACT. THE INDENTURE
REFERRED TO HEREINAFTER CONTAINS A PROVISION REQUIRING THE REGISTRAR APPOINTED
THEREUNDER TO REFUSE TO REGISTER ANY TRANSFER OF THIS NOTE IN VIOLATION OF THE
FOREGOING RESTRICTIONS.

BY ITS PURCHASE AND ACCEPTANCE OF THIS NOTE, EACH PURCHASER WILL BE DEEMED TO HAVE
REPRESENTED AND WARRANTED THAT EITHER (I) NO PLAN ASSETS WILL BE USED TO PURCHASE
THIS NOTE OR (II) PLAN ASSETS WILL BE USED TO PURCHASE THIS NOTE BUT (A) THE
PURCHASE, HOLDING AND DISPOSITION OF THIS NOTE WILL NOT CONSTITUTE A NON-EXEMPT
PROHIBITED TRANSACTION UNDER THE EMPLOYEE RETIREMENT INCOME SECURITY ACT OF 1974, AS
AMENDED (“ERISA”), OR THE INTERNAL REVENUE CODE OF 1986, AS AMENDED (THE “CODE”), BY
REASON OF THE APPLICATION OF ONE OR MORE STATUTORY OR ADMINISTRATIVE EXEMPTIONS OR
OTHERWISE AND WILL NOT CONSTITUTE A VIOLATION OF SIMILAR LAWS OR (B) SUCH ASSETS ARE
NOT CONSIDERED PLAN ASSETS BY REASON OF BEING HELD IN A SEPARATE ACCOUNT OF AN
INSURANCE COMPANY, UNDER WHICH AMOUNTS PAYABLE OR CREDITED TO THE PLAN AND TO ANY
PARTICIPANT OR BENEFICIARY OF THE PLAN ARE NOT AFFECTED BY THE INVESTMENT
PERFORMANCE OF THE SEPARATE ACCOUNT. “PLAN ASSETS” HAS THE MEANING GIVEN TO IT BY
SECTION 3(42) OF ERISA AND REGULATIONS OF THE DEPARTMENT OF LABOR, BUT ALSO INCLUDES
ASSETS OF AN EMPLOYEE BENEFIT PLAN (WITHIN THE MEANING OF SECTION 3(3) OF ERISA)
SUBJECT TO

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LAWS OR REGULATIONS THAT ARE SUBSTANTIALLY SIMILAR TO SECTION 406 OF
ERISA OR SECTION 4975 OF THE CODE.

THIS NOTE MAY NOT BE RESOLD OR TRANSFERRED EXCEPT AS SET FORTH IN THE INDENTURE
REFERRED TO HEREINAFTER, AND, IN ADDITION, EACH PERSON WHO ACQUIRES OR ACCEPTS THIS
NOTE OR AN INTEREST HEREIN BY SUCH ACQUISITION OR ACCEPTANCE AGREES THAT IT SHALL
CAUSE ANY PROPOSED TRANSFEREE TO EXECUTE A CONFIDENTIALITY AGREEMENT IN THE FORM
ATTACHED AS EXHIBIT B TO SUCH INDENTURE AND DELIVER SUCH CONFIDENTIALITY AGREEMENT
TO THE REGISTRAR (AS DEFINED IN SUCH INDENTURE) AND FURTHER AGREES TO OTHERWISE
COMPLY WITH THE TRANSFER RESTRICTIONS SET FORTH IN SUCH INDENTURE, INCLUDING SECTION
2.11 THEREOF, AND FURTHER ACKNOWLEDGES AND AGREES TO THE PROVISIONS SET FORTH IN
SECTION 2.5 OF SUCH INDENTURE.

THIS NOTE WAS ISSUED WITH ORIGINAL ISSUE DISCOUNT (“OID”) FOR UNITED STATES FEDERAL
INCOME TAX PURPOSES. UPON REQUEST TO THE ISSUER, THE ISSUER WILL PROMPTLY CAUSE TO
BE MADE AVAILABLE, TO THE HOLDER OF THIS NOTE, INFORMATION REGARDING THE ISSUE
PRICE, THE ISSUE DATE AND THE YIELD TO MATURITY OF, AND THE AMOUNT OF OID IN RESPECT
OF, THIS NOTE.

BY ITS ACQUISITION HEREOF, THE HOLDER ACKNOWLEDGES THAT THIS NOTE (OR ANY BENEFICIAL
INTEREST THEREIN) MAY NOT BE EXCHANGED OR TRANSFERRED IF, IMMEDIATELY AFTER SUCH
EXCHANGE OR TRANSFER, THERE WOULD BE MORE THAN 95 NOTEHOLDERS (IN THE CASE OF NOTES
THAT ARE DEFINITIVE NOTES) OR BENEFICIAL HOLDERS (IN THE CASE OF NOTES THAT ARE
GLOBAL NOTES), TAKEN TOGETHER IN THE AGGREGATE, AND ANY SUCH PURPORTED EXCHANGE OR
TRANSFER SHALL BE VOID AB INITIO.

Each Global Note shall also bear the following legend on the face thereof:

UNLESS THIS NOTE IS PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY
TRUST COMPANY TO THE ISSUER OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR
PAYMENT, AND ANY NOTE ISSUED IS REGISTERED IN THE NAME OF CEDE & CO. OR TO SUCH
OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST
COMPANY (AND ANY PAYMENT HEREON IS
MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED
REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY), ANY TRANSFER, PLEDGE OR OTHER USE
HEREOF FOR

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VALUE OR OTHERWISE BY OR TO ANY PERSON IS WRONGFUL SINCE THE REGISTERED
OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN.

TRANSFERS OF THIS NOTE SHALL BE LIMITED TO TRANSFERS IN WHOLE, BUT NOT IN PART, TO
NOMINEES OF CEDE & CO. OR TO A SUCCESSOR THEREOF OR SUCH SUCCESSOR’S NOMINEE AND
TRANSFERS OF PORTIONS OF THIS NOTE SHALL BE LIMITED TO TRANSFERS MADE IN ACCORDANCE
WITH THE RESTRICTIONS SET FORTH IN SECTION 2.11 OF THE INDENTURE REFERRED TO
HEREINAFTER.

     Each Temporary Regulation S Global Note shall also bear the following legend on the face
thereof:

THIS NOTE IS A TEMPORARY REGULATION S GLOBAL NOTE WITHIN THE MEANING OF THE
INDENTURE REFERRED TO HEREINAFTER AND IS SUBJECT TO RESTRICTIONS ON THE TRANSFER AND
EXCHANGE THEREOF AND ON THE PAYMENT OF INTEREST THEREON AS SPECIFIED IN THE
INDENTURE REFERRED TO HEREINAFTER.

     Section 2.3 Registrar, Paying Agent and Calculation Agent.

          (a) With respect to each class of Notes, there shall at all times be maintained an office or
agency in the location set forth in Section 12.5 where the Notes of such class may be presented or
surrendered for registration of transfer or for exchange (including any additional registrar, each,
a “Registrar”) and for payment thereof (including any additional paying agent, each, a
“Paying Agent”) and where notices and demands to or upon the Issuer in respect of such
Notes may be served. The Trustee shall be the initial Paying Agent and Registrar, and the Issuer
shall not be permitted to act as a Paying Agent or a Registrar. The Issuer shall cause each
Registrar to keep a register of such class of Notes for which it is acting as Registrar and of
their transfer and exchange (the “Register”). Written notice of the location of each such
other office or agency and of any change of location thereof shall be given by the Trustee to the
Issuer and the Noteholders of such class of Notes. In the event that no such office or agency
shall be maintained or no such notice of location or of change of location shall be given,
presentations and demands may be made and notices may be served at the Corporate Trust Office.

          (b) The Trustee shall act as the Calculation Agent hereunder. To the extent not otherwise
specifically provided herein, the Trustee shall furnish to the Calculation Agent, and the
Calculation Agent shall furnish to the Trustee, upon written request such information and copies of
such documents as the Trustee or the Calculation Agent may have and as are necessary for the
Calculation Agent and the Trustee to perform their respective duties under Article III or
otherwise.

          (c) Each Authorized Agent shall be a bank, trust company or corporation organized and doing
business under the laws of the U.S., any state or territory thereof or of the

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District of Columbia,
with a combined capital and surplus of at least $75,000,000 (or having a combined capital and
surplus in excess of $5,000,000 and the obligations of which, whether now in existence or hereafter
incurred, are fully and unconditionally Guaranteed by a bank, trust company or corporation
organized and doing business under the laws of the U.S., any state or territory thereof or of the
District of Columbia and having a combined capital and surplus of at least $75,000,000) and shall
be authorized under the laws of the U.S., any state or territory thereof or the District of
Columbia to exercise corporate trust powers, subject to supervision by federal or state authorities
(such requirements, the “Eligibility Requirements”). Each Registrar other than the Trustee
shall furnish to the Trustee, at least five Business Days prior to each Payment Date, and at such
other times as the Trustee may request in writing, a copy of the Register maintained by such
Registrar.

          (d) Any Person into which any Authorized Agent may be merged or converted or with which it may
be consolidated, or any Person resulting from any merger, consolidation or conversion to which any
Authorized Agent shall be a party, or any Person succeeding to all or substantially all of the
corporate trust business of any Authorized Agent (including the administration of the fiduciary
relationship contemplated by this Indenture), shall be the successor of such Authorized Agent
hereunder, if such successor is otherwise eligible under this Section 2.3, without the execution or
filing of any paper or any further act on the part of the parties hereto or such Authorized Agent
or such successor Person.

          (e) Any Authorized Agent may at any time resign by giving written notice of resignation to the
Trustee and the Issuer. The Issuer may, and at the request of the Trustee shall, at any time
terminate the agency of any Authorized Agent by giving written notice of termination to such
Authorized Agent and to the Trustee. Upon the resignation or termination of an Authorized Agent or
if at any time any such Authorized Agent shall cease to be eligible under this Section 2.3 (when,
in either case, no other Authorized Agent performing the functions of such Authorized Agent shall
have been appointed by the Trustee), the Issuer shall promptly appoint one or more qualified
successor Authorized Agents, reasonably satisfactory to the Trustee, to perform the functions of
the Authorized Agent that has resigned or whose agency has been terminated or who shall have ceased
to be eligible under this Section 2.3. The Issuer shall give written notice of any such
appointment made by it to the Trustee, and in each case the Trustee shall mail notice of such
appointment to all Noteholders of the related class of Notes as their names and addresses appear on
the Register for such class of Notes.

          (f) The Issuer agrees to pay, or cause to be paid, from time to time to each Authorized Agent
reasonable compensation for its services and to reimburse it for its reasonable expenses to be
agreed to pursuant to separate agreements with each such Authorized Agent.

     Section 2.4 Paying Agent to Hold Money in Trust. The Trustee shall require each Paying Agent
other than the Trustee to agree in writing that all moneys deposited with any Paying Agent for the
purpose of any payment on the Notes shall be deposited and held in trust for the benefit of the
Noteholders entitled to such payment, subject to the provisions of this Section 2.4. Moneys so
deposited and held in trust shall
constitute a separate trust fund for the benefit of the Noteholders with respect to which such
money was deposited.

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     The Trustee may at any time, for the purpose of obtaining the satisfaction and discharge of
this Indenture or for any other purpose, direct any Paying Agent to pay to the Trustee all sums
held in trust by such Paying Agent, and, upon such payment by any Paying Agent to the Trustee, such
Paying Agent shall be released from all further liability with respect to such money.

     Section 2.5 Method of Payment.

          (a) On each Payment Date, the Trustee shall, or shall instruct a Paying Agent to, pay, subject
to Section 3.7, to the extent of the Available Collections Amount for such Payment Date and any
funds withdrawn from the Interest Reserve Account or the Capital Account by the Trustee pursuant to
Section 3.8, to the Noteholders all interest, principal and Premium, if any, on each class of Notes
in the amounts determined by the Calculation Agent pursuant to Section 3.5; provided, that
payment on a Temporary Regulation S Global Note shall be made to the Noteholder thereof only in
conformity with Section 2.5(c) and payment on any Note may be deferred as provided in Section
2.5(d). Each payment on any Payment Date other than the final payment with respect to any class of
Notes shall be made by the Trustee or Paying Agent to the Noteholders as of the Record Date for
such Payment Date. The final payment with respect to any class of Notes, however, shall be made
only upon presentation and surrender of such Note by the Noteholder or its agent at an office or
agency of the Trustee or Paying Agent in New York City.

          (b) Subject to Section 2.5(d), at such time, if any, as the Notes of any class are issued in
the form of Definitive Notes, payments on a Payment Date shall be made by the Trustee or the Paying
Agent by check mailed to each Noteholder of a Definitive Note on the applicable Record Date at its
address appearing on the Register maintained with respect to such class of Notes. Alternatively,
upon application in writing to the Trustee, not later than the applicable Record Date, by a
Noteholder holding Definitive Notes with an Outstanding Principal Balance of at least $5,000,000,
subject to Section 2.5(d), any such payments shall be made by wire transfer to an account
designated by such Noteholder at a financial institution in New York City; provided, that,
in each case, the final payment for any class of Notes shall be made only upon presentation and
surrender of the Definitive Notes of such class by the Noteholder or its agent at an office or
agency of the Trustee or Paying Agent in New York City. Payments in respect of the Notes
represented by a Global Note (including principal, Premium, if any, and interest) shall be made by
wire transfer of immediately available funds to the account specified by DTC at a financial
institution in New York City.

          (c) The beneficial owner of a Temporary Regulation S Global Note may arrange to receive
payments through Euroclear or Clearstream on such Temporary Regulation S Global Note only after
delivery by such beneficial owner to Euroclear or Clearstream, as the case may be, of a written
certification substantially in the form of Exhibit G and upon delivery by Euroclear or
Clearstream, as the case may be, to the Paying Agent of a certification or certifications
substantially in the form of Exhibit H. No interest shall be paid to any beneficial owner
and no interest shall be paid to Euroclear or Clearstream on such beneficial owner’s
interest in a Temporary Regulation S Global Note unless Euroclear or Clearstream, as the case
may be, has provided such a certification to the Paying Agent with respect to such interest.

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          (d) Not later than five Business Days prior to each Payment Date or any other date on which a
Distribution Report is to be distributed to Noteholders and Beneficial Holders pursuant to Section
2.13(a), the Registrar shall use commercially reasonable efforts to (i) prepare a list (the
“Approved Holder List”) of each Noteholder and Beneficial Holder as of the Record Date
related to such Payment Date that has executed and delivered to the Registrar a Confidentiality
Agreement, (ii) obtain from DTC a list (the “DTC List”) of the Agent Members holding
Beneficial Interests in the Notes as of such Record Date, (iii) obtain from each such Agent Member
as of such Record Date the corresponding Beneficial Holders of the Beneficial Interests held by
each such Agent Member set forth on the DTC List as of such Record Date and prepare a list thereof
and of the Beneficial Interests owned by each such Beneficial Holder (the “Actual Beneficial
Holder List”), (iv) prepare a list (the “Escrow List”), if necessary, that identifies
any differences between (x) the Noteholders and Beneficial Holders listed on the Approved Holder
List and (y)(A) the Noteholders of Definitive Notes set forth in the Register and (B) the
Beneficial Holders listed on the Actual Beneficial Holder List (or those Beneficial Holders that
the Registrar actually knows have not executed and delivered to the Registrar Confidentiality
Agreements), in each case as of such Record Date, and (v) provide the Approved Holder List, the DTC
List, the Actual Beneficial Holder List and any Escrow List to the Issuer, the Servicer and the
Trustee. Each Noteholder, Agent Member and Beneficial Holder hereby agrees, acknowledges and
consents that (I) with respect to a Noteholder of any Notes (other than DTC or its nominee) that as
of such Record Date has not executed and delivered to the Registrar a Confidentiality Agreement
and, therefore, is listed on the Escrow List, the Trustee promptly (but in no event less than three
Business Days prior to the applicable Payment Date) shall use commercially reasonable efforts to
notify such Noteholder of such failure and, on the applicable Payment Date, if so instructed in
writing by the Issuer, cause any principal payment with respect to the Outstanding Principal
Balance or any payment of Premium, if any, or Interest Amount on such Notes to be paid directly to
the Escrow Account and (II) with respect to a Beneficial Holder of any Beneficial Interest in a
Note that as of such Record Date has not executed and delivered to the Registrar a Confidentiality
Agreement and, therefore, is listed on the Escrow List, the Trustee promptly (but in no event less
than three Business Days prior to the applicable Payment Date) shall use commercially reasonable
efforts to cause the Beneficial Interest of such Beneficial Holder to be transferred into the name
of the Trustee (including the Trustee acting as an Agent Member with respect to such Beneficial
Interests) and shall use commercially reasonable efforts to cause any payment of principal,
Premium, if any, or interest on such Notes or Beneficial Interests received on such Payment Date,
if so instructed in writing by the Issuer, to be deposited into the Escrow Account upon receipt
thereof. If so deposited into the Escrow Account, upon receipt by the Trustee and the Issuer of
written notice from the Registrar that the applicable Noteholder or Beneficial Holder has executed
and delivered to the Registrar a Confidentiality Agreement, the Trustee will distribute such
amounts, without interest, from the Escrow Account to the Trustee for distribution to each such
Noteholder or Beneficial Holder, but prior to the receipt thereof the Trustee shall be authorized
to treat such purported Noteholder or Beneficial Holder as not being a Noteholder or Beneficial
Holder, as the case may be, for purposes of this Indenture. If any purported Noteholder or
Beneficial Holder has not executed and delivered to the Registrar a Confidentiality Agreement, the
Issuer may, at its option, by delivery of an Officer’s Certificate to the Trustee, authorize the
Trustee to remove any Notes held by such
purported Noteholder or Beneficial Holder from the book-entry systems of DTC, Clearstream and
Euroclear and instead have such Notes be issued in definitive form until such time as receipt

14

 

by
the Trustee and the Issuer of written notice from the Registrar that such purported Noteholder or
Beneficial Holder has executed and delivered to the Registrar a Confidentiality Agreement. The
Trustee shall so remove such Notes immediately upon receipt of such Officer’s Certificate.

          (e) To the extent that the full Interest Amount due on the Class A Notes is not paid in full
on any Payment Date and funds are deposited into the Collection Account or the Capital Account
following such Payment Date but prior to the third Business Day prior to the immediately succeeding
Calculation Date, at the written direction of the Issuer (and, in the case of the Capital Account,
the Equityholder), only to the extent of dollars on deposit in the Collection Account and, if
directed by the Issuer and the Equityholder, the Capital Account, notwithstanding anything to the
contrary in this Indenture, the Trustee shall use such funds (subject to the requirement in Section
3.8 that such a withdrawal shall be made from the Capital Account only once) to pay to the
Noteholders of record the overdue Interest Amount; provided, that all Expenses with respect
to such preceding Payment Date contemplated by Section 3.7(a)(ii) and all Expenses for which the
Issuer has previously submitted supporting documentation pursuant to and as contemplated by Section
3.7(c), in each case, shall have been paid. With each such payment, the Trustee shall furnish a
brief statement to Noteholders eligible to receive Distribution Reports in accordance with this
Indenture indicating the aggregate amount of funds received and the balance of the unpaid Interest
Amount (together with Additional Interest thereon) to which the payment is being applied. Subject
to Section 2.5(d), any such payment shall be made to the Noteholders of record as of the third
Business Day preceding the date of each such payment. Any funds that are deposited on or after the
third Business Day prior to the immediately succeeding Calculation Date shall be held in the
Collection Account or the Capital Account, as applicable, and applied in accordance with this
Indenture on the next succeeding Payment Date.

          (f) The payment of any Interest Amount in respect of a class of Notes on a particular Payment
Date shall be deemed allocated first to any unpaid Interest Amount due prior to such Payment Date
(together with Additional Interest thereon) and second to any Interest Amount due on such Payment
Date.

     Section 2.6 Minimum Denominations. Each class of Notes shall be issued in minimum denominations
of $250,000 or integral multiples of $1,000 in excess thereof.

     Section 2.7 Transfer and Exchange; Cancellation. The Notes are issuable only in fully registered
form without coupons. A Noteholder or a Beneficial Holder may transfer a Note or a Beneficial
Interest therein only by written application to the Registrar stating the name of the proposed
transferee and otherwise complying with the terms of this Indenture, including the requirement for
the execution and delivery of a Confidentiality Agreement by such proposed transferee to the
Registrar relating to such transfer as set forth in Section 2.11(j). No such transfer shall be
effected until, and such proposed transferee shall succeed to the rights of a Noteholder or a
Beneficial Holder only upon, final
acceptance and registration of the transfer by the Registrar and confirmation by the Registrar
pursuant to Section 2.11(j) that such Noteholder or such Beneficial Holder has executed and
delivered an appropriate Confidentiality Agreement to the Registrar.

15

 

     Prior to the due presentment for registration of transfer of a Note and satisfaction of the
requirements specified in the last sentence of the preceding paragraph, the Issuer and the Trustee
may deem and treat the applicable registered Noteholder as the absolute owner and holder of such
Note for the purpose of receiving payment of all amounts payable with respect to such Note and for
all other purposes and shall not be affected by any notice to the contrary. The Registrar (if
different from the Trustee) shall promptly notify the Trustee in writing and the Trustee shall
promptly notify the Issuer of each request for a registration of transfer of a Note by furnishing
the Issuer a copy of such request.

     Furthermore, any Noteholder of a Global Note shall, by acceptance of such Global Note, agree
that, subject to Section 2.10(b) and Section 2.11, transfers of Beneficial Interests in such Global
Note may be effected only through a book-entry system maintained by the Noteholder of such Global
Note (or its agent) and that ownership of a Beneficial Interest in such Global Note shall be
required to be reflected in a book-entry system. When Notes are presented to the Registrar with a
request to register the transfer or to exchange them for an equal principal amount of Notes of
other authorized denominations, the Registrar shall register the transfer or make the exchange as
requested if its requirements for such transactions are met (including, in the case of a transfer,
that such Notes are duly endorsed or accompanied by a written instrument of transfer in form
satisfactory to the Trustee and Registrar duly executed by the Noteholder thereof or by an attorney
who is authorized in writing to act on behalf of the Noteholder). To permit registrations of
transfers and exchanges, the Issuer shall execute and the Trustee shall authenticate Notes at the
Registrar’s request. Except as set forth in Section 2.8 and Section 2.9, no service charge shall
be made for any registration of transfer or exchange or redemption of the Notes.

     The Registrar shall not be required to exchange or register the transfer of any Notes as above
provided during the 15-day period preceding the Final Legal Maturity Date of any such Notes or
during a 15-day period preceding the first mailing of any notice of Redemption or Refinancing of
Notes to be redeemed or refinanced. The Registrar shall not be required to exchange or register
the transfer of any Notes that have been selected, called or are being called for Redemption or
Refinancing except, in the case of any Notes where written notice has been given that such Notes
are to be redeemed in part, the portion thereof not so to be redeemed.

     Any Person (including the Issuer) at any time may deliver Notes to the Trustee for
cancellation. The Trustee and no one else shall cancel and destroy in accordance with its
customary practices in effect from time to time (subject to the record retention requirements of
the Exchange Act) any such Notes, together with any other Notes surrendered to it for registration
of transfer, exchange or payment. The Issuer may not issue new Notes (other than Refinancing Notes
issued in connection with any Refinancing) to replace Notes it (or any other Person) has redeemed,
paid or delivered to the Trustee for cancellation.

     Section 2.8 Mutilated, Destroyed, Lost or Stolen Notes. If any Note shall become mutilated, destroyed, lost or stolen, the Issuer shall, upon the
written request of the Noteholder thereof and presentation of the Note or satisfactory evidence of
destruction, loss or theft thereof to the Trustee or Registrar and a confirmation by the Registrar
to the Trustee that such Noteholder (or Beneficial Holder of the Beneficial Interest therein) has
executed and delivered to the Registrar a Confidentiality Agreement, issue, and the Trustee shall
authenticate and the

16

 

Trustee or Registrar shall deliver in exchange therefor or in replacement
thereof, a new Note, payable to such Noteholder in the same principal amount, of the same maturity,
with the same payment schedule, bearing the same interest rate and dated the date of its
authentication. If the Note being replaced has become mutilated, such Note shall be surrendered to
the Trustee or the Registrar and forwarded to the Issuer by the Trustee or such Registrar. If the
Note being replaced has been destroyed, lost or stolen, the Noteholder thereof shall furnish to the
Issuer, the Trustee and the Registrar (a) such security or indemnity as may be required by the
Issuer, the Trustee and the Registrar to save each of them harmless (an unsecured indemnity from
any QIB being satisfactory security or indemnity) and (b) evidence satisfactory to the Issuer, the
Trustee and the Registrar of the destruction, loss or theft of such Note and of the ownership
thereof (an affidavit from any QIB being satisfactory evidence). The Noteholders will be required
to pay any Tax or other governmental charge imposed in connection with such exchange or replacement
and any other expenses (including the reasonable fees and expenses of the Trustee and the
Registrar) connected therewith.

     Section 2.9 Payments of Transfer Taxes. Upon the transfer of any Note or Notes pursuant to
Section 2.7, the Issuer or the Trustee may require from the party requesting such new Note or Notes
payment of a sum to reimburse the Issuer or the Trustee for, or to provide funds for the payment
of, any transfer Tax or similar governmental charge payable in connection therewith.

     Section 2.10 Book-Entry Provisions.

          (a) Global Notes shall (i) be registered in the name of DTC or a nominee of DTC, (ii) be
delivered to the Trustee as custodian for DTC and (iii) bear the Legend. In accordance with the
requirements of DTC, the Issuer will cause the Trustee to authenticate an additional Global Note or
additional Global Notes in the appropriate principal amount such that no Global Note may exceed an
aggregate principal amount of $500,000,000 at any time.

     Members of, or participants in, DTC (“Agent Members”) shall have no rights under this
Indenture with respect to any Global Note held on their behalf by DTC, or the Trustee as its
custodian, or under such Global Note, and DTC may be treated by the Issuer, the Trustee and any
agent of the Issuer or the Trustee as the absolute owner of such Global Note for all purposes
whatsoever.

     Whenever notice or other communication to the Noteholders of any class of Global Notes is
required under this Indenture, unless and until Definitive Notes shall have been issued pursuant to
Section 2.10(b), the Trustee shall give all such notices and communications specified herein to be
given to Noteholders of such class of Global Notes to DTC and/or the Agent Members, and shall make
available additional copies as requested by such Agent Members, subject to the limitations on
distribution contained in Section 2.13.

     Notwithstanding the foregoing, nothing herein shall prevent the Issuer, the Trustee or any
agent of the Issuer or the Trustee from giving effect to any written certification, proxy or other
authorization furnished by DTC or impair, as between DTC and its Agent Members, the operation of
customary practices governing the exercise of the rights of a Noteholder under any Global Note.
Neither the Issuer nor the Trustee shall be liable for any delay by DTC in

17

 

identifying the Agent
Members in respect of the Global Notes, and the Issuer and the Trustee may conclusively rely on,
and shall be fully protected in relying on, instructions from DTC for all purposes (including with
respect to the registration and delivery, and the respective principal amounts, of any Global Notes
to be issued).

          (b) Transfers of a Global Note shall be limited to transfers of such Global Note in whole, but
not in part, to DTC, its successors or their respective nominees. Interests of Agent Members in a
Global Note may be transferred in accordance with the rules and procedures of DTC and the
provisions of Section 2.11. Except as set forth in Section 2.5(d) and Section 2.11(a), Definitive
Notes shall be issued to the individual Agent Members or Beneficial Holders or their nominees in
exchange for their Beneficial Interests in a Global Note with respect to any class of Notes only if
(i) the Issuer advises the Trustee in writing that DTC is no longer willing or able to properly
discharge its responsibilities as depositary with respect to such class of Notes and the Trustee or
the Issuer is unable to appoint a qualified successor within 90 days of such notice or (ii) during
the occurrence of an Event of Default with respect to such class of Notes, any Noteholder requests
that all or a portion of a Global Note be exchanged for a Definitive Note. Upon the occurrence of
any event described in the immediately preceding sentence, the Trustee shall notify all affected
Noteholders of such class, through DTC, of the occurrence of such event and of the availability of
Definitive Notes of such class; provided, however, that in no event shall the
Temporary Regulation S Global Note be exchanged for Definitive Notes prior to the later of (x) the
Regulation S Global Note Exchange Date and (y) the date of receipt by the Issuer of any
certificates determined by it to be required pursuant to Rule 903 or 904 under the Securities Act.
Upon surrender to the Trustee of the Global Notes of such class held by DTC, accompanied by
registration instructions from DTC for registration of Definitive Notes, the Issuer shall issue and
the Trustee shall authenticate and deliver the Definitive Notes of such class to the Agent Members
and Beneficial Holders of such class or their nominees in accordance with the instructions of DTC.

     None of the Issuer, the Registrar, the Paying Agent or the Trustee shall be liable for any
delay in delivery of such instructions and may conclusively rely on, and shall be fully protected
in relying on, such registration instructions. Upon the issuance of Definitive Notes of such
class, subject to Section 2.5(d), the Trustee shall recognize the Persons in whose name the
Definitive Notes are registered in the Register as Noteholders hereunder. Neither the Issuer nor
the Trustee shall be liable if the Trustee or the Issuer is unable to locate a qualified successor
to DTC.

     Definitive Notes of any class will be freely transferable and exchangeable for Definitive
Notes of the same class at the office of the Trustee or the office of the Registrar upon compliance
with the requirements set forth in this Indenture. In the case of a transfer of only part of a
holding of Definitive Notes, a new Definitive Note shall be issued to the transferee in respect of
the part transferred and a new Definitive Note in respect of the balance of the holding not
transferred shall be issued to the transferor and may be obtained at the office of the applicable
Registrar.

          (c) Any Beneficial Interest in one of the Global Notes as to any class that is transferred to
a Person who takes delivery in the form of an interest in another Global Note will, upon transfer,
cease to be an interest in such Global Note and become an interest in such other Global Note and,
accordingly, will thereafter be subject to all transfer restrictions, if any, and

18

 

other procedures
applicable to Beneficial Interests in such other Global Note for as long as it remains such an
interest.

          (d) Any Definitive Note delivered in exchange for an interest in a Global Note pursuant to
Section 2.5(d) or Section 2.10(b) shall bear the Legend applicable to a Global Note.

     Section 2.11 Special Transfer Provisions.

          (a) The following provisions shall apply with respect to any proposed transfer of a Beneficial
Interest in a 144A Global Note or a Permanent Regulation S Global Note or a proposed transfer of a
Definitive Note to any Institutional Accredited Investor that is not a QIB (excluding Non-U.S.
Persons):

          (i) The Registrar shall register the transfer of any Definitive Note if the proposed
transferee has delivered to the Registrar (A) a certificate substantially in the form of
Exhibit J (such certificate also to be delivered to the Issuer), (B) if requested by
the Issuer or the Trustee, an Opinion of Counsel acceptable to the Issuer that such transfer
is in compliance with the Securities Act and (C) a Confidentiality Agreement duly executed
by such transferee.

          (ii) If the proposed transferor is an Agent Member holding a Beneficial Interest in a
144A Global Note or a Permanent Regulation S Global Note, upon receipt by the Registrar of
(A) the documents required by Section 2.11(a)(i), including the Confidentiality Agreement,
and (B) instructions given in accordance with DTC’s and the Registrar’s procedures, the
Registrar shall reflect on its books and records the date and a decrease in the principal
amount of the 144A Global Note or the Permanent Regulation S Global Note, as the case may
be, in an amount equal to the principal amount of the Beneficial Interest in the Global Note
to be transferred, and the Issuer shall execute, and the Trustee shall authenticate and
deliver, one or more Definitive Notes of like tenor and amount.

          (b) The following provisions shall apply with respect to any proposed transfer of a Beneficial
Interest in a 144A Global Note or a Permanent Regulation S Global Note or a proposed transfer of a
Definitive Note to a QIB (excluding Non-U.S. Persons):

          (i) If the Note to be transferred consists of (A) Definitive Notes, the Registrar shall
reflect the transfer on its books and records if such transfer is being made by a proposed
transferor who has delivered such Note and checked the box provided for on the form of Note
stating, or has otherwise advised the Issuer and the Registrar in writing, that the sale has
been made in compliance with the provisions of Rule 144A to a transferee who has signed the
certification provided for on the form of Note stating, or has otherwise advised the Issuer
and the Registrar in writing, that (w) it is purchasing the Note for its own account or an
account with respect to which it exercises sole investment
discretion and that it and any such account are QIBs within the meaning of Rule 144A,
(x) it is or such QIBs are aware that the sale to it or them is being made in reliance on
Rule 144A and acknowledge that it has or they have received such information regarding the
Issuer as it has or they have requested pursuant to Rule 144A or has or have

19

 

determined not
to request such information, (y) it is or such QIBs are aware that the transferor is relying
upon the foregoing representations in order to claim the exemption from registration
provided by Rule 144A and (z) it has and all such QIBs have duly executed and delivered to
the Registrar a Confidentiality Agreement or (B) a Beneficial Interest in a 144A Global
Note, the transfer of such Beneficial Interest may be effected only through the book-entry
system maintained by DTC and to the extent provided in the agreement with DTC, and, in each
case, each transferee has delivered to the Registrar a Confidentiality Agreement duly
executed by such transferee.

          (ii) If the proposed transferee is an Agent Member, and the Note to be transferred is a
Definitive Note, upon receipt by the Registrar of the documents referred to in Section
2.11(b)(i), including the Confidentiality Agreement, and instructions given in accordance
with DTC’s and the Registrar’s procedures, the Registrar shall reflect on its books and
records the date and an increase in the principal amount at maturity of the 144A Global Note
in an amount equal to the principal amount at maturity of the Definitive Note to be
transferred, and the Trustee shall cancel the Definitive Note so transferred (upon written
direction from the Registrar if different from the Trustee).

          (iii) If the proposed transferee is an Agent Member, and the Note to be transferred is
represented by a Beneficial Interest in a Permanent Regulation S Global Note, upon receipt
by the Registrar of the documents referred to in Section 2.11(b)(i), including the
Confidentiality Agreement, and instructions given in accordance with DTC’s and the
Registrar’s procedures, the Registrar shall reflect on its books and records the date and a
decrease in the principal amount of the Permanent Regulation S Global Note in an amount
equal to the principal amount of the Beneficial Interest in the Permanent Regulation S
Global Note to be transferred, and the Registrar shall reflect on its books and records an
increase in the principal amount of the 144A Global Note in an amount equal to such
transferred amount.

          (c) With respect to any proposed transfer of a Beneficial Interest in a Temporary Regulation S
Global Note to an Institutional Accredited Investor, the Registrar shall reflect on its books and
records the transfer of such Beneficial Interest (A) if the proposed transferee is a Non-U.S.
Person, the proposed transferor has delivered to the Registrar a certificate substantially in the
form of Exhibit I (such certificate also to be delivered to the Issuer) and the proposed
transferee has duly executed and delivered to the Registrar a Confidentiality Agreement (in which
case the transferee will receive a corresponding Beneficial Interest in the Temporary Regulation S
Global Note) or (B) if the proposed transferee is a QIB and the proposed transferor has checked the
box provided for on the form of Note stating, or has otherwise advised the Issuer and the Registrar
in writing, that the sale has been made in compliance with the provisions of Rule 144A to a
transferee who has signed the certification provided for on the form of Note stating, or has
otherwise advised the Issuer and the Registrar in writing, that (w) it is purchasing the Note (or
the Beneficial Interest therein) for its own account or an account with respect to which it
exercises sole investment discretion and that it and any such account are QIBs within
the meaning of Rule 144A, (x) it is or such QIBs are aware that the
sale to it or them is
being made in reliance on Rule 144A and acknowledge that it has or they have received such
information regarding the Issuer as it has or they have requested pursuant to Rule 144A or has or
have determined not to request such information, (y) it is or such QIBs are aware that the

20

 

transferor is relying upon the foregoing representations in order to claim the exemption from
registration provided by Rule 144A and (z) it has and all such QIBs have duly executed and
delivered to the Registrar a Confidentiality Agreement (in which case the Registrar shall reflect
on its books and records the date and an increase in the principal amount of the 144A Global Note
of the relevant class, in an amount equal to the principal amount of the Temporary Regulation S
Global Note (or the Beneficial Interest therein) of such class to be transferred, and the Trustee
shall decrease the amount of the Temporary Regulation S Global Note of such class (upon written
direction from the Registrar if different from the Trustee)).

          (d) Except as set forth in Section 2.11(c), the following provisions shall apply with respect
to any transfer of a Note (or a Beneficial Interest therein) to a Non-U.S. Person:

          (i) Except as set forth in Section 2.11(c), prior to the applicable Regulation S Global
Note Exchange Date, the Registrar shall not register or reflect on its books and records any
proposed transfer of a Note (or a Beneficial Interest therein) to a Non-U.S. Person.

          (ii) The Registrar shall register or reflect on its books and records, as the case may
be, any proposed transfer of a Note (or a Beneficial Interest therein) to any Non-U.S.
Person that is an Institutional Accredited Investor if the Note to be transferred is a
Definitive Note or a Beneficial Interest in a 144A Global Note, upon receipt of a
certificate substantially in the form of Exhibit I from the proposed transferor and
a Confidentiality Agreement duly executed and delivered to the Registrar by such Non-U.S.
Person that is an Institutional Accredited Investor.

          (iii) (A) If the proposed transferor is an Agent Member holding a Beneficial Interest
in a 144A Global Note, upon receipt by the Registrar of (x) the documents, if any, required
by Section 2.11(d)(ii) and (y) instructions in accordance with DTC’s and the Registrar’s
procedures, the Registrar shall reflect on its books and records the date and a decrease in
the principal amount of the 144A Global Note in an amount equal to the principal amount of
the Beneficial Interest in such 144A Global Note to be transferred, and (B) if the proposed
transferee is an Agent Member, upon receipt by the Registrar of instructions given in
accordance with DTC’s and the Registrar’s procedures, the Registrar shall reflect on its
books and records the date and an increase in the principal amount of the Permanent
Regulation S Global Note of the relevant class in an amount equal to the principal amount of
the Beneficial Interest in such 144A Global Note or any Definitive Notes issued in exchange
for such Beneficial Interest in such 144A Global Note to be transferred, and the Trustee
shall cancel the Definitive Note, if any, so transferred or decrease the amount of the 144A
Global Note (upon written direction from the Registrar if different from the Trustee).

          (e) With respect to any proposed transfer of any Note (or a Beneficial Interest therein), the
Registrar shall reflect the transfer of such Note or Beneficial Interest on its books
and records (along with any appropriate increase or decrease in the principal amount at
maturity of any Global Note upon receipt by the Registrar of instructions given in accordance with
DTC’s and the Registrar’s procedures) if the proposed transferee has duly executed and delivered to
the Registrar a Confidentiality Agreement.

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          (f) Upon the transfer, exchange or replacement of Notes bearing the Legend, the
Registrar shall deliver only Notes that bear the Legend.

          (g) By its acceptance of any Note bearing the Legend, each Noteholder of such Note
acknowledges the restrictions on transfer of such Note set forth in this Indenture and in the
Legend and agrees that it will transfer such Note (or the Beneficial Interest therein) only as
provided in this Indenture and in accordance with the Legend. The Registrar shall not register or
reflect on its books and records a transfer of any Note (or any Beneficial Interest therein) unless
such transfer complies with the restrictions on transfer of such Note set forth in this Indenture
and in accordance with the Legend. In connection with any transfer of Notes (or Beneficial
Interests therein), each Noteholder (or Beneficial Holder) agrees by its acceptance of the Notes
(or Beneficial Interests therein) to furnish the Trustee the certifications and legal opinions (if
requested and required pursuant hereto) described herein to confirm that such transfer is being
made pursuant to an exemption from, or a transaction not subject to, the registration requirements
of the Securities Act; provided, that the Trustee shall not be required to determine (but
may rely on a determination made by the Issuer with respect to) the sufficiency of any such legal
opinions.

          (h) The Notes shall be issued pursuant to an exemption from registration under the Securities
Act. The Issuer agrees that it will not at any time (i) apply to list, list or list upon notice of
issuance, (ii) consent to or authorize an application for the listing or the listing of, or (iii)
enable or authorize the trading of, the Notes on an established securities market, including (w) a
national securities exchange registered under the Exchange Act or exempted from registration
because of the limited volume of transactions, (x) a foreign securities exchange that, under the
law of the jurisdiction where it is organized, satisfies regulatory requirements that are analogous
to the regulatory requirements under the Exchange Act applicable to exchanges described in Section
2.11(h)(iii)(w), (y) a regional or local exchange or (z) an over-the-counter market or interdealer
quotation system that regularly disseminates firm buy or sell quotations by identified brokers or
dealers by electronic means or otherwise, as the term “established securities market” and the terms
in this Section 2.11(h) are defined for purposes of Section 7704 of the Code.

          (i) The Trustee shall retain copies of all letters, notices and other written communications
received pursuant to Section 2.10 or this Section 2.11. The Issuer shall have the right to inspect
and make copies of all such letters, notices, Confidentiality Agreements or other written
communications at any reasonable time upon the giving of reasonable written notice to the Trustee.

          (j) Each Noteholder, Agent Member and Beneficial Holder agrees, by acceptance of any Note or
any Beneficial Interest therein, that it will not take any action to transfer any Note (or any
Beneficial Interest therein) to a proposed transferee without causing such proposed transferee to
execute and deliver to the Registrar an appropriate Confidentiality Agreement relating to such
transfer as set forth in this Section 2.11. After the Closing Date with respect to the Original
Class A Notes (or the date of issuance with respect to any Subordinated Notes or any Refinancing
Notes), forms of Confidentiality Agreements will be available to Noteholders, Agent Members and
Beneficial Holders and proposed transferees of the Notes (or the Beneficial Interests therein) from
the Registrar, initially at the Corporate Trust Office. Each

22

 

such Confidentiality Agreement shall be delivered to the Registrar promptly upon execution by the
parties thereto and the Registrar shall record the receipt of such Confidentiality Agreement. The
Registrar shall promptly, but in any event no later than two Business Days after receipt of any
such executed Confidentiality Agreement, furnish a copy of such executed Confidentiality Agreement
to the Trustee, the Issuer and the Servicer and shall maintain a list of proposed transferees
(including Noteholders and Beneficial Holders) who have furnished such executed Confidentiality
Agreements, whether or not such proposed transferees purchase any Notes (or any Beneficial
Interests therein), and make such list available for inspection at the request of the Trustee, the
Issuer or the Servicer.

          (k) Notwithstanding any other provision contained in this Indenture to the contrary, any
Noteholder or Beneficial Holder may assign a security interest in, or pledge, all or any portion of
the Notes (or any interest therein) held by it to a lender or a trustee or collateral agent (or
other similar representative) under any indenture, loan agreement or similar agreement to which
such Noteholder or Beneficial Holder is party in support of any obligations of such Noteholder or
Beneficial Holder to a holder or holders of securities or other obligations issued by such
Noteholder or Beneficial Holder; provided, that no such assignment or pledge shall release
the assigning or pledging Noteholder or Beneficial Holder from its obligations hereunder;
provided, further, that any assignee or pledgee shall be required to execute and
deliver to the Registrar an appropriate Confidentiality Agreement as a condition of such assignment
or pledge.

     Section
2.12 Temporary Definitive Notes. Pending the preparation of Definitive Notes of any class,
the Issuer may execute and the Trustee may authenticate and deliver temporary Definitive Notes of
such class that are printed, lithographed, typewritten or otherwise produced, in any denomination,
containing substantially the same terms and provisions as are set forth in the applicable Exhibit
or in any indenture supplemental hereto, except for such appropriate insertions, omissions,
substitutions and other variations relating to their temporary nature as a Responsible Officer of
the Issuer executing such temporary Definitive Notes may determine, as evidenced by his or her
execution of such temporary Definitive Notes.

     If temporary Definitive Notes of any class are issued, the Issuer shall cause such Definitive
Notes of such class to be prepared without unreasonable delay. After the preparation of Definitive
Notes of such class, the temporary Definitive Notes shall be exchangeable for Definitive Notes upon
surrender of such temporary Definitive Notes at the Corporate Trust Office, without charge to the
Noteholder thereof. Upon surrender for cancellation of any one or more temporary Definitive Notes
of any class, the Issuer shall execute and the Trustee shall authenticate and deliver in exchange
therefor Definitive Notes of like class, in authorized denominations and in the same aggregate
principal amounts. Until so exchanged, such temporary Definitive Notes shall in all respects be
entitled to the same benefits under this Indenture as Definitive Notes.

     Section 2.13 Statements to Noteholders.

          (a) On each Payment Date and any other date for distribution of any payments with respect to
any class of Notes then Outstanding, the Trustee shall deliver a report, covering
the information set forth in Exhibit D and prepared by the Servicer, giving effect to
such payments (each, a “Distribution Report”), to (i) each Noteholder and Beneficial Holder
included

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on the Approved Holder List, (ii) the Issuer, (iii) the Calculation Agent and (iv) the
Equityholders, and to no other Person. Each Noteholder and Beneficial Holder shall be entitled to
receive a Distribution Report only if such Noteholder or Beneficial Holder has executed and
delivered to the Registrar a Confidentiality Agreement.

          (b) Each Distribution Report provided to each Noteholder and Beneficial Holder by the Trustee
for each Payment Date pursuant to Section 2.13(a), commencing September 1, 2011, shall be
accompanied by (i) a statement prepared by the Servicer setting forth an analysis of the Collection
Account activity for the period commencing on the day next following the preceding Calculation Date
and ending on the Calculation Date relating to such Payment Date and which shall set forth, among
other things, the aggregate amount payable or paid to the Seller pursuant to Section 3.4 and (ii)
the information with respect to collections and payments, if any, that the Issuer shall have
provided to the Trustee pursuant to Section 5.3 (or the Servicer shall have provided to the Trustee
pursuant to Section 3.1 of the Servicing Agreement) during the Interest Accrual Period then ended
(including any reports produced by Counterparty pursuant to Section 9.3(f) of the Counterparty
License Agreement, documentation evidencing the receipt and calculation of any Currency Hedge
Payments and documentation evidencing the exchange of yen to dollars pursuant to Section 3.12 or
pursuant to the Currency Hedge Agreement (including the rate of exchange and calculation of the
amounts payable in respect of such exchange)), all of which information shall be treated
confidentially pursuant to the terms of the Confidentiality Agreement. Notwithstanding the
foregoing, the Trustee shall distribute, within five Business Days of the Trustee’s receipt from
the Servicer, any reports that the Servicer indicates in writing were produced by Counterparty
pursuant to Section 9.3(f) of the Counterparty License Agreement to each Noteholder and Beneficial
Holder included on the Approved Holder List.

          (c) After the end of each calendar year but not later than the latest date permitted by law,
the Trustee shall (or shall instruct any Paying Agent to) furnish to each Person who at any time
during such calendar year was a Noteholder of any class of Notes a statement (for example, a Form
1099 or any other means required by law) prepared by the Trustee containing the sum of the amounts
determined pursuant to the information covered by Exhibit D with respect to the class of
Notes for such calendar year or, in the event such Person was a Noteholder of any class of Notes
during only a portion of such calendar year, for the applicable portion of such calendar year, and
such other items as are readily available to the Trustee and that a Noteholder shall reasonably
request as necessary for the purpose of such Noteholder’s preparation of its U.S. federal income or
other tax returns. So long as any of the Notes are registered in the name of DTC or its nominee,
such report and such other items will be prepared on the basis of such information supplied to the
Trustee by DTC and the Agent Members and will be delivered by the Trustee to DTC and by DTC to the
applicable Beneficial Holders in the manner described above. In the event that any such
information has been provided by any Paying Agent directly to such Person through other tax-related
reports or otherwise, the Trustee in its capacity as Paying Agent shall not be obligated to comply
with such request for information.

          (d) At such time, if any, as the Notes of any class are issued in the form of Definitive
Notes, the Trustee shall prepare and deliver the information described in Section
2.13(c) to each Noteholder of a Definitive Note of such class for the relevant period of
registered ownership of such Definitive Note as appears on the books and records of the Trustee,
subject to

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confirmation that each such Noteholder has executed and delivered to the Registrar a
Confidentiality Agreement.

          (e) The Trustee shall be at liberty to sanction any method of giving notice to the Noteholders
of any class if, in its opinion, such method is reasonable, having regard to the number and
identity of the Noteholders of such class and/or to market practice then prevailing, is in the best
interests of the Noteholders of such class, and any such notice shall be deemed to have been given
on such date as the Trustee may approve; provided, that notice of such method is given to
the Noteholders of such class in such manner as the Trustee shall require.

     Section 2.14
Identification Numbers. The Issuer in issuing the Notes may use CUSIP, CINS, ISIN,
private placement or other identification numbers (if then generally in use), and, if so, the
Trustee shall use such CUSIP, CINS, ISIN, private placement or other identification numbers, as the
case may be, in notices of redemption or exchange as a convenience to Noteholders;
provided, that any such notice shall state that no representation is made as to the
correctness of such numbers either as printed on the Notes or as contained in any notice of
redemption or exchange and that reliance may be placed only on the other identification numbers
printed on the Notes; provided, further, that failure to use CUSIP, CINS, ISIN,
private placement or other identification numbers in any notice of redemption or exchange shall not
affect the validity or sufficiency of such notice.

     Section 2.15 Refinancing Notes.

          (a) Subject to Section 2.15(b), Section 2.15(c) and Section 2.15(d), the Issuer may issue
Refinancing Notes pursuant to this Indenture solely for the purpose of refinancing all, but not
part, of the Outstanding Principal Balance of any class of Notes (including a refinancing of
Refinancing Notes). Each refinancing of any class of Notes with the proceeds of an offering of
Refinancing Notes (a “Refinancing”) shall be authorized pursuant to one or more
Resolutions. Each Refinancing Note shall be designated generally as a Note for all purposes under
this Indenture, with such further designations added or incorporated in such title as specified in
the related Resolution and set forth in any indenture supplemental hereto providing for the
issuance of such Notes or specified in the form of such Notes, as the case may be. The Refinancing
Notes shall be issued on the Redemption Date on which the Redemption in whole of the class of Notes
being refinanced is to occur as provided in Section 3.10 and shall rank equal in priority relative
to the class of Notes being refinanced.

          (b) A Refinancing of any class of Notes shall be effected as a Redemption pursuant to Section
3.9, provided that a Refinancing of the Original Class A Notes shall be effected as an Optional
Redemption pursuant to Section 3.9(b). On the date of any Refinancing, the Issuer shall issue and
sell an aggregate principal amount of Refinancing Notes (when added to the Available Collections
Amount and any funds in the Interest Reserve Account, the Redemption Account or the Capital Account
used or to be used in connection with such Refinancing) resulting in proceeds in an amount
sufficient to pay in full the applicable Redemption Price of the Notes being refinanced in whole
thereby plus the Refinancing Expenses
relating thereto. The proceeds of each sale of Refinancing Notes shall be used to the extent
necessary to make the deposit required by Section 3.10 and to pay such Refinancing Expenses.
Subject to Section 3.10(b), once a notice of a Redemption in respect of any Refinancing is

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published in accordance with Section 3.10(a), each class of Notes to which such notice applies
shall become due and payable on the Redemption Date stated in such notice at their Redemption
Price.

          (c) Each Refinancing Note shall contain such terms as may be established in or pursuant to the
related Resolution (subject to Section 2.1) and set forth in any indenture supplemental hereto
providing for the issuance of such Notes or specified in the form of such Notes to the extent
permitted below. Prior to the issuance of any Refinancing Notes, any or all of the following, as
applicable, with respect to the related issue of Refinancing Notes shall have been determined by
the Issuer and set forth in such Resolution and in any indenture supplemental hereto providing for
the issuance of such Notes or specified in the form of such Notes, as the case may be:

          (i) the class of Notes to be refinanced by such Refinancing Notes;

          (ii) the aggregate principal amount of each class of Refinancing Notes that may be
issued in respect of such Refinancing;

          (iii) the proposed date of such Refinancing;

          (iv) the Final Legal Maturity Date of each class of such Refinancing Notes;

          (v) the rate at which such Refinancing Notes shall bear interest or the method by which
such rate shall be determined;

          (vi) the denomination or denominations in which any class of such Refinancing Notes
shall be issuable;

          (vii) whether such Refinancing Notes will be subject to redemption pursuant to Section
3.9(c);

          (viii) whether any such Refinancing Notes are to be issuable initially in temporary or
permanent global form and, if so, whether beneficial owners of interests in any such
permanent global Refinancing Note may exchange such interests for Refinancing Notes of such
class and of like tenor and of any authorized form and denomination and the circumstances
under which any such exchanges may occur, if other than in the manner provided in Section
2.7, and the circumstances under which and the place or places where any such exchanges may
be made and the identity of any initial depositary therefor; and

          (ix) any other terms, conditions, rights and preferences (or limitations on such rights
and preferences) relating to the class of Refinancing Notes (which terms shall comply with
Applicable Law and not violate any restrictions of this Indenture).

          (d) If any of the terms of any issue of Refinancing Notes are established by action taken
pursuant to one or more Resolutions, such Resolutions shall be delivered to the Trustee setting
forth the terms of such Refinancing Notes.

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     Section 2.16 Subordinated Notes.

          (a) Subject to Section 2.16(b), Section 2.16(c) and Section 2.16(d), the Issuer may issue
Subordinated Notes pursuant to this Indenture (each, a “Subordinated Note Issuance”) for
any purpose, including, at the option of the Issuer, for the purpose of funding a redemption of the
Class A Notes, in whole or in part. Each Subordinated Note Issuance shall be authorized pursuant
to one or more Resolutions. Each Subordinated Note shall be designated generally as a Note for all
purposes under this Indenture. Each Subordinated Note shall have such further designations added
or incorporated in such title as specified in the related Resolution and set forth in any indenture
supplemental hereto providing for the issuance of such Notes or specified in the form of such
Notes, as the case may be. There are no limitations on the use of proceeds from the issuance of
any such Subordinated Notes, including making dividends or distributions to the Equityholders and
redeeming the Class A Notes in whole or in part. If the proceeds of any Subordinated Notes are
being used to redeem the Class A Notes, in whole or in part, such Subordinated Notes shall be
issued on the Redemption Date on which the Optional Redemption of the Class A Notes being
refinanced is to occur as provided in Section 3.10.

          (b) If the proceeds of any Subordinated Notes are being used to redeem any Class A Notes, such
redemption shall be effected as an Optional Redemption pursuant to Section 3.9(b). On the date of
any such Optional Redemption, the Issuer shall issue and sell an aggregate principal amount of
Subordinated Notes in an amount not less than the amount sufficient to pay in full the applicable
Redemption Price of the Notes being redeemed thereby plus the Transaction Expenses relating
thereto. The proceeds of each sale of such Subordinated Notes shall be used to make the deposit
required by Section 3.10, to the extent applicable, to pay such Transaction Expenses and/or for
such other purposes, if any, as shall be specified in the Resolution authorizing the issuance of
such Subordinated Notes. Subject to Section 3.10(b), once a notice of Redemption in respect of any
Subordinated Note Issuance is published in accordance with Section 3.10(a), each class of Notes to
which such notice applies shall become due and payable on the Redemption Date stated in such notice
at their Redemption Price.

          (c) Each Subordinated Note shall contain such terms as may be established in or pursuant to
the related Resolution (subject to Section 2.1) and set forth in any indenture supplemental hereto
providing for the issuance of such Notes or specified in the form of such Notes to the extent
permitted herein, shall rank in priority relative to any other classes (or sub-classes) of
Subordinated Notes as specified in such Resolution and set forth in an indenture supplemental
hereto and, in any event, shall be subordinate to the Class A Notes to the extent provided in this
Indenture. Prior to the issuance of any such Subordinated Notes, any or all of the following, as
applicable, with respect to the related Subordinated Note Issuance shall have been determined by
the Issuer and set forth in such Resolution and in any indenture supplemental hereto or specified
in the form of such Subordinated Notes, as the case may be, with respect to the such Subordinated
Notes to be issued:

          (i) the aggregate principal amount of any such Subordinated Notes that may be issued;

          (ii) the proposed date of such Subordinated Note Issuance;

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          (iii) the Final Legal Maturity Date of any such Subordinated Notes;

          (iv) whether any such Subordinated Notes are to have the benefit of any reserve account
and, if so, the amount and terms thereof;

          (v) the rate at which such Subordinated Notes shall bear interest or the method by
which such rate shall be determined;

          (vi) the denomination or denominations in which such Subordinated Notes shall be
issuable;

          (vii) whether such Subordinated Notes will be subject to redemption pursuant to Section
3.9(c);

          (viii) whether any such Subordinated Notes are to be issuable initially in temporary or
permanent global form and, if so, whether beneficial owners of interests in any such
permanent global Subordinated Note may exchange such interests for Subordinated Notes of
like tenor and of any authorized form and denomination and the circumstances under which any
such exchanges may occur, if other than in the manner provided in Section 2.7, and the
circumstances under which and the place or places where any such exchanges may be made and
the identity of any initial depositary therefor;

          (ix) the ranking in priority of such Subordinated Notes relative to any other classes
(or sub-classes) of Subordinated Notes;

          (x) the use of proceeds of such Subordinated Note Issuance; and

          (xi) any other terms, conditions, rights and preferences (or limitations on such rights
and preferences) relating to such Subordinated Notes (which terms shall comply with
Applicable Law and not violate any restrictions of this Indenture).

          (d) If any of the terms of any issue of Subordinated Notes are established by action taken
pursuant to one or more Resolutions, such Resolutions shall be delivered to the Trustee setting
forth the terms of such Subordinated Notes.

          (e) Any Subordinated Notes shall be subordinated to the Class A Notes pursuant to the priority
of payment provisions under this Indenture, and no payments of principal, interest or Premium, if
any, may be made on such Subordinated Notes from the Available Collections Amount until the Class A
Notes have been paid in full. In addition, while any Class A Notes are Outstanding, Subordinated
Notes may only be redeemed by the Issuer with proceeds from Refinancing Notes in respect of such
Subordinated Notes or capital contributions from the Equityholders.

     Section 2.17 Limitation on Number of Holders of Notes. The Issuer shall not issue, and the
Registrar shall not issue or exchange or register the transfer of, any Note if, immediately after
such issuance, exchange or transfer, there would be more than 95 Noteholders (in the case of Notes
that are Definitive Notes) or Beneficial Holders (in the case of Notes that are Global Notes),
taken together in the aggregate, and any purported issuance, exchange or transfer in

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violation of this Section 2.17 shall be void ab initio and result in the purported Noteholder
or Beneficial Holder not being treated as a Noteholder or Beneficial Holder, as the case may be,
for purposes of this Indenture. The Issuer shall (i) immediately notify the Registrar if the
Issuer has actual knowledge that there are more than 95 Noteholders and Beneficial Holders, taken
together in the aggregate (an “Excess Holder Event”), and (ii) furnish to the Registrar
such additional information available to it as the Registrar may reasonably request from time to
time to permit the Registrar to prepare the Approved Holder Lists, the DTC Lists, the Actual
Beneficial Holder Lists and the Escrow Lists (collectively, the “Holder Lists”) pursuant to
Section 2.5(d). In determining whether an Excess Holder Event has occurred, or for any other
purpose under this Indenture, the Registrar may assume without further inquiry that the only
Noteholders and Beneficial Holders that it must take into consideration are those named in the most
recently updated Holder Lists maintained by the Registrar. For the avoidance of doubt, neither the
Trustee nor the Registrar is required to inquire into or update the Holder Lists except as required
by Section 2.5(d).

ARTICLE III

ACCOUNTS; PRIORITY OF PAYMENTS

     Section 3.1 Establishment of Accounts.

          (a) Pursuant to the terms of the Servicing Agreement, the Issuer will cause the Servicer,
acting on behalf of the Issuer, to establish and maintain with the Operating Bank on its books and
records in the name of the Issuer, subject to the Liens established under this Indenture, (i) a
collection account (the “Collection Account”), (ii) a redemption account (the
“Redemption Account”), (iii) a capital contribution account (the “Capital
Account”), (iv) an escrow account (the “Escrow Account”), (v) an interest reserve
account (the “Interest Reserve Account”) and (vi) any additional accounts the establishment
of which is set forth in a Resolution delivered by the Issuer to the Servicer and the Trustee, in
each case at such time as is set forth in this Section 3.1 or in such Resolution. Each Account
(other than the Escrow Account) shall be established and maintained as an Eligible Account so as to
create, perfect and establish the priority of the Liens established under this Indenture in such
Account (other than the Escrow Account) and all cash, Eligible Investments and other property from
time to time deposited therein and otherwise to effectuate the Liens under this Indenture.

          (b) The Trustee as the Operating Bank shall have sole dominion and control over the Accounts
(other than the Escrow Account) (including, among other things, the sole power to direct
withdrawals or transfers from such Accounts and to direct the investment and reinvestment of funds
in such Accounts, subject to Section 3.2). The Trustee as the Operating Bank shall make
withdrawals and transfers from the Accounts in accordance with the terms of this Indenture based on
the Relevant Information and as calculated by it pursuant to this Indenture. Each of the Issuer
and the Trustee as the Operating Bank acknowledges and agrees that the Accounts (other
than the Escrow Account) are “deposit accounts” or “investment property” within the meaning of
Section 9-102 of the UCC and that the Trustee has “control”, for purposes of Section 9-314 of the
UCC, of such Accounts (other than the Escrow Account) that are maintained with the Trustee as the
Operating Bank. The Issuer agrees that, if any Account (other than the Escrow Account) is
established or maintained with any Operating Bank other than the Trustee, the Issuer shall direct
the Servicer to cause such Operating Bank to enter into an agreement with the Trustee, the

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Issuer and the Servicer pursuant to which such Operating Bank agrees to comply with any and all
instructions of the Trustee directing the disposition, investment and reinvestment of funds in all
Accounts (other than the Escrow Account) maintained with such Operating Bank without the further
consent of the Issuer (or the Servicer), and the Issuer shall take such other actions as are
reasonably required by the Trustee to establish its “control”, for purposes of Section 9-314 of the
UCC, over any such Accounts (other than the Escrow Account). The Trustee as the Operating Bank
hereby confirms that it has established the following accounts in the name of the Issuer: (a) the
Collection Account (account number 145651000); (b) the Redemption Account (account number
145651002); (c) the Capital Account (account number 145651004); (d) the Escrow Account (account
number 145651003); and (e) the Interest Reserve Account (account number 145651005) (collectively,
the “Closing Day Accounts”). The Trustee, the Issuer and the Trustee as the Operating Bank
hereby agree that (i) the Trustee as the Operating Bank shall comply with all instructions
originated by the Trustee directing the disposition of funds in any Closing Day Account or any
other Account maintained with the Trustee as the Operating Bank (other than the Escrow Account) and
all entitlement orders originated by the Trustee with respect to any Closing Day Account or any
other Account (other than the Escrow Account), in each case without further consent by the Issuer,
and (ii) the jurisdiction of the Trustee as the Operating Bank for purposes of the UCC shall be the
State of New York.

          (c) If, at any time, any Account (other than the Escrow Account) ceases to be an Eligible
Account, the Issuer will cause the Servicer or an agent thereof to, within ten Business Days,
establish a new Account meeting the conditions set forth in this Section 3.1 in respect of such
Account and transfer any cash or investments in the existing Account to such new Account, and, from
the date such new Account is established, it shall have the same designation as the existing
Account. If the Operating Bank should change at any time, then the Issuer will cause the Servicer,
acting on behalf of the Issuer, to thereupon promptly establish replacement Accounts as necessary
at the successor Operating Bank and transfer the balance of funds in each Account then maintained
at the former Operating Bank pursuant to the terms of the Servicing Agreement to such successor
Operating Bank.

          (d) The Issuer will cause the Servicer to maintain the Collection Account at the Operating
Bank not later than the Closing Date, and the Collection Account shall bear a designation clearly
indicating that the funds or other assets deposited therein are held for the benefit of the
Trustee. Except as expressly provided herein, all Collections shall be deposited in the Collection
Account and transferred therefrom in accordance with the terms of this Indenture. No funds shall
be deposited in the Collection Account that do not constitute Collections, except as expressly
provided in this Indenture, without the prior written consent of the Trustee.

          (e) The Issuer will cause the Servicer to maintain the Redemption Account at the Operating
Bank that shall bear a designation clearly indicating that the funds or other assets deposited
therein are held for the benefit of the Trustee, who shall hold such amounts for the
benefit of the Noteholders of Notes that are the subject of such Redemption. All amounts
received for the purpose of any such Redemption shall be deposited in such Redemption Account and
shall be held in such Account until such amounts are applied to pay the Redemption Price of such
Notes (together with related Expenses) and such Notes are cancelled by the Trustee.

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          (f) The Issuer will cause the Servicer to maintain the Capital Account at the Operating Bank
not later than the Closing Date, and the Capital Account shall bear a designation clearly
indicating that the funds or other assets deposited therein are held for the benefit of the
Trustee. Except as expressly provided herein, all capital contributions made to the Issuer shall
be deposited and held in the Capital Account and transferred therefrom (i) to the Noteholders in
payment of any Interest Amount in accordance with Section 3.8, (ii) on the Final Legal Maturity
Date, to the Noteholders in payment of the Outstanding Principal Balance in accordance with Section
3.8, (iii) to the Redemption Account only to the extent specifically provided for in any written
notice of an Optional Redemption delivered to the Trustee pursuant to Section 3.9(b), (iv) to the
Equityholders only to the extent permitted by Section 5.2(b) (solely as relates to the issuance of
Capital Securities of the Issuer in accordance with such Section 5.2(b)) and (v) to the
Equityholders only to the extent permitted by Section 3.8.

          (g) The Issuer will cause the Servicer to maintain the Escrow Account at the Operating Bank in
the name of the Trustee that shall bear a designation clearly indicating that the funds or other
assets deposited therein are held for the benefit of any such Noteholder, Agent Member or
Beneficial Holder. All amounts withheld from such Noteholder, Agent Member or Beneficial Holder
pursuant to Section 2.5(d) shall be deposited in such Escrow Account and shall be held in such
Escrow Account until such amounts are distributed as provided in Section 2.5(d).

          (h) The Issuer will cause the Servicer to maintain the Interest Reserve Account at the
Operating Bank that shall bear a designation clearly indicating that the funds deposited therein
are held for the benefit of the Trustee. Amounts shall be deposited into the Interest Reserve
Account only pursuant to Section 3.3(a)(iii) or Section 3.8. All such amounts shall be held in
such Interest Reserve Account and transferred therefrom only pursuant to Section 3.8.

     Section 3.2 Investments of Cash. So long as no Event of Default has occurred and is continuing,
the Servicer may direct the Trustee in writing to invest and reinvest the funds on deposit in the
Collection Account and the Interest Reserve Account in Eligible Investments, to the extent such
Eligible Investments are available to the relevant Operating Bank, and advise the Trustee in
writing of any depository institution or trust company described in the proviso to the definition
of Eligible Investments; provided, however, that, so long as an Event of Default
has occurred and is continuing, the Trustee shall direct each Operating Bank to invest such amount
in Eligible Investments described in clause (a) of the definition thereof from the time of receipt
thereof until such time as such amounts are required to be distributed pursuant to the terms of
this Indenture. In the absence of written direction delivered to the Trustee from the Servicer,
the Trustee shall direct each Operating Bank to invest any funds in Eligible Investments described
in clause (a) of the definition thereof. The Trustee shall direct each Operating Bank to make such
investments and reinvestments in accordance with the terms of the following provisions:

          (a) the Eligible Investments shall have maturities and other terms such that sufficient funds
shall be available to make required payments pursuant to this Indenture on the Business Day
immediately preceding the next occurring Payment Date after such investment is made;

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          (b) if any funds to be invested are received in the Accounts after 1:00 p.m., New York City
time, on any Business Day, such funds shall, if possible, be invested in overnight Eligible
Investments;

          (c) all interest and earnings on Eligible Investments held in the Accounts shall be invested
in Eligible Investments on an overnight basis and credited to the appropriate Account until the
next Payment Date; and

          (d) the Issuer acknowledges that regulations of the U.S. Comptroller of the Currency grant the
Issuer the right to receive confirmations of security transactions as they occur, and the Issuer
specifically waives receipt of such confirmations to the extent permitted by Applicable Law and
acknowledges that the Operating Bank will instead furnish monthly cash transaction statements that
will detail all investment transactions as set forth in this Indenture.

     Section 3.3 Payments and Transfers in connection with Issuance of Notes.

          (a) On the Closing Date, the Trustee shall, subject to the receipt of written direction from
the Issuer, upon receipt of the Note Purchase Price from the sale by the Issuer of the Original
Class A Notes, make the following payments from such proceeds in the amounts so directed by the
Issuer:

          (i) to such Persons and in such amounts as shall be specified by the Issuer, such
Transaction Expenses as shall be due and payable in connection with the issuance and sale of
the Notes;

          (ii) to the Seller, in accordance with the Purchase and Sale Agreement, the amount by
which the Note Purchase Price exceeds the sum of (x) such Transaction Expenses and (y) the
Initial Interest Reserve Amount; and

          (iii) to the Interest Reserve Account, the Initial Interest Reserve Amount.

          (b) On the date of issuance of any Subordinated Notes or any Refinancing Notes, the Trustee
shall, subject to the receipt of written direction from the Issuer upon receipt of the proceeds of
the sale by the Issuer of such Notes, make such payments and transfers as shall be specified in
this Indenture, the related Resolution and any indenture supplemental hereto in respect of such
Notes, copies of which Resolution and indenture supplemental hereto shall be attached to such
written direction.

          (c) The Trustee shall hold all funds received on or prior to the Closing Date from the Note
Purchasers in trust for the Note Purchasers pending the Closing Date. Upon receipt by the Trustee
of the aggregate Note Purchase Price from all Note Purchasers, the Trustee shall disburse the Note
Purchase Price in accordance with this Section 3.3. If the aggregate Note Purchase Price shall not
have been received by the Trustee by 3:30 p.m. (New York City time)
on the Closing Date, or if the closing of the transactions contemplated by the Purchase
Agreements shall not otherwise be capable of being consummated by 3:30 p.m. (New York City time) on
the Closing Date, then each Note Purchaser who has paid its respective portion of the Note Purchase
Price shall have the right to instruct the Trustee in writing at or after 3:30 p.m. (New York City
time) on the Closing Date to return such portion of the Note Purchase Price to

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such Note Purchaser
prior to the close of business on the Closing Date or as soon thereafter as reasonably practicable.

     Section 3.4 Seller Payments. Subject to Section 11.2, within ten Business Days of receipt of
Royalties (whether denominated in dollars or yen) in the Collection Account from Counterparty, the
Trustee shall remit 4% of the gross amount of such Royalties (the “Seller Payments”) to the
Seller at such account or accounts as the Seller shall designate in writing to the Trustee.

     Section 3.5 Calculation Date Calculations.

          (a) As soon as reasonably practicable after each Calculation Date (a “Relevant Calculation
Date”), but in no event later than 12:00 noon (New York City time) on the second Business Day
prior to the immediately succeeding Payment Date, the Calculation Agent shall, based on the
Calculation Date Information received by the Calculation Agent, and based on information known to
it or Relevant Information provided to it, make the following determinations and calculations (and
each of the Trustee and the Issuer (for itself and on behalf of the Servicer) agrees to provide any
Relevant Information reasonably requested by the Calculation Agent for the purpose of making such
determinations and calculations):

          (i) the Available Collections Amount for such Payment Date;

          (ii) (x) the amount of Collections received during the period commencing on the day
immediately following the Calculation Date that immediately preceded such Relevant
Calculation Date and ending on such Relevant Calculation Date and (y) the amount, if any, to
be transferred from the Interest Reserve Account and the Capital Account as of the Relevant
Calculation Date to the Collection Account on such Payment Date in accordance with Section
3.8 and as calculated pursuant to Section 3.5(a)(x);

          (iii) the balance of funds on deposit in each Account other than the Collection Account
on such Relevant Calculation Date and the amount of interest and earnings (net of losses and
investment expenses), if any, on investments of funds on deposit therein from the day
immediately following the Calculation Date that immediately preceded such Relevant
Calculation Date and ending on such Relevant Calculation Date;

          (iv) the balance of funds on deposit in the Collection Account on such Relevant
Calculation Date and the amount of interest and earnings (net of losses and investment
expenses), if any, on investments of funds on deposit therein from the day immediately
following the Calculation Date that immediately preceded such Relevant Calculation Date and
ending on such Relevant Calculation Date;

          (v) Taxes owed by the Issuer;

          (vi) the amounts that have been paid or otherwise become payable to the Seller pursuant
to Section 3.4 from the day immediately following the Calculation Date that immediately
preceded such Relevant Calculation Date and ending on such Relevant Calculation Date;

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          (vii) (x) all other Expenses due and payable on such Payment Date and not previously
paid or reimbursed, and to be paid or reimbursed, pursuant to Section 3.7(a)(ii), in the
amounts shown on all supporting documentation therefor and attached to the Calculation Date
Information received by the Calculation Agent, and (y) all Expenses previously reimbursed
and paid to the Issuer in respect of Expenses pursuant to Section 3.7(c) from the day
immediately following the Calculation Date that immediately preceded such Relevant
Calculation Date and ending on such Relevant Calculation Date;

          (viii) the applicable interest rate on each class of Floating Rate Notes (if any)
determined on the Reference Date for the Interest Accrual Period beginning on such Payment
Date and the Interest Amount (including any Additional Interest) on each class of Floating
Rate Notes and Fixed Rate Notes for such Payment Date;

          (ix) if such Payment Date is a Redemption Date on which a Redemption of Notes is
scheduled to occur, the amount necessary to pay the Redemption Price (and related Expenses)
of the Notes to be repaid on such Redemption Date and the Redemption Premium, if any, to be
paid as part of such Redemption Price;

          (x) the Interest Amount due to Noteholders of Class A Notes on such Payment Date and
the difference, if any, between the Interest Amount due to the Noteholders of Class A Notes
on such Payment Date and the Available Collections Amount for such Payment Date, after
giving effect to the payment of all amounts to be paid or reimbursed on such Payment Date
pursuant to Section 3.7(a)(i) and Section 3.7(a)(ii) (such difference, an “Interest
Shortfall”), and, with respect to each Interest Shortfall, the amount to be withdrawn
from the Interest Reserve Account and/or the Capital Account, if any, determined as provided
in Section 3.8;

          (xi) the Outstanding Principal Balance of each class of Notes on such Payment Date
immediately prior to any principal payment with respect to the Outstanding Principal Balance
on such Payment Date and the amount of any principal payment with respect to the Outstanding
Principal Balance to be made in respect of each class of Notes on such Payment Date, taking
into account the other payments to be made on such Payment Date entitled to priority
pursuant to Section 3.7;

          (xii) the amounts, if any, distributable to the Issuer on such Payment Date pursuant to
Section 3.7(a)(viii);

          (xiii) the amount of the Seller Shortfall Payment, if any, to be made on such Payment
Date pursuant to Section 3.11;

          (xiv) any amounts payable to the Interest Reserve Account on such Payment Date pursuant
to Section 3.7(a)(iv); and

          (xv) any other information, determinations and calculations reasonably required in
order to give effect to the terms of this Indenture and the other Deal Documents.

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          (b) Following the calculations and determinations by the Calculation Agent described in
Section 3.5(a), and not later than 1:00 p.m., New York City time, on the second Business Day
prior to the immediately succeeding Payment Date, the Calculation Agent shall provide to
each of the Issuer, the Servicer and the Trustee a calculation report (a “Calculation
Report”) listing the determinations and calculations set forth in Section 3.5(a).

     Section 3.6
Payment Date First Step Transfers. On each Payment Date, the Trustee shall transfer
from any Account (other than the Collection Account and the Capital Account) to the Collection
Account the amount of interest and earnings (net of losses and investment expenses), if any, earned
as a result of investments of funds on deposit therein from the day immediately following the
Calculation Date that immediately preceded the Relevant Calculation Date and ending on the Relevant
Calculation Date.

     Section 3.7 Payment Date Second Step Withdrawals.

          (a) Subject to Section 3.4 and Section 3.7(d), on each Payment Date, after the applicable
transfers provided for in Section 3.6 have been made, after the making of any Seller Shortfall
Payment pursuant to Section 3.11 and after giving effect to Section 3.7(e), the Trustee shall
distribute (or instruct the Paying Agent to distribute) from the Collection Account the amounts set
forth below in the order of priority set forth below but, in each case, only to the extent that all
amounts then required to be paid ranking prior thereto have been paid in full:

          (i) first, to the Issuer for the payment of all Taxes owed by the Issuer, if
any;

          (ii) second, to the payment of all Expenses not previously paid or reimbursed,
in the amounts shown in all supporting documentation attached to the Calculation Date
Information received by the Calculation Agent;

          (iii) third, to the Trustee for distribution to the Noteholders of the Class A
Notes, the ratable payment of the Interest Amount then due and payable on the Class A Notes,
taking into account any amounts previously paid pursuant to Section 2.5(e) and any
adjustment to be made pursuant to Section 3.7(d) and any amounts to be paid pursuant to
Section 3.8, in each case on such Payment Date;

          (iv) fourth, as long as no Event of Default has occurred and is continuing, on
the September 1, 2014 Payment Date, the September 1, 2015 Payment Date or the September 1,
2016 Payment Date, to the Interest Reserve Account, the amount set forth in a written
direction to the Trustee from the Issuer on or prior to the related Calculation
Date; provided, that such application of funds, together with any such prior
application of funds, shall not exceed $2,100,000 in the aggregate;

          (v) fifth, to the Trustee for distribution to the Noteholders of the Class A
Notes, principal payments with respect to the Outstanding Principal Balance on the Class A
Notes (without Premium or penalty), allocated pro rata in proportion to the Outstanding
Principal Balance of such Class A Notes held by such Noteholders, until the Outstanding
Principal Balance of the Class A Notes has been paid in full;

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          (vi) sixth, after the Class A Notes have been paid in full, to the Trustee for
distribution to the Noteholders of the Subordinated Notes, if any, the principal amount of
and any Interest Amount on the Subordinated Notes in accordance with the terms of the
Subordinated Notes, until the Subordinated Notes have been paid in full;

          (vii) seventh, after the Notes have been paid in full, to the ratable payment
of all other obligations under this Indenture until all such amounts are paid in full; and

          (viii) eighth, after the Notes and all amounts owing under clause (vii) above
have been paid in full, to the Issuer, all remaining amounts.

          (b) To the extent the Issuer receives amounts from the Trustee from the Collection Account
pursuant to Section 3.7(a)(viii), such amounts may be distributed by the Issuer to the
Equityholders (or as otherwise directed by the Equityholders or any Person designated by the
Equityholders to give such directions) in their sole discretion. The provisions contained in this
Section 3.7(b) may not be amended, modified, waived or terminated (including pursuant to any
termination of this Indenture) without the prior written consent of the Equityholders materially
and adversely affected thereby, and the provisions contained in this Section 3.7(b) shall survive
the termination of this Indenture. The parties hereto specifically agree that each Equityholder
materially and adversely affected thereby (i) is and shall be an express third-party beneficiary of
the provisions of this Section 3.7(b) and (ii) shall have the right to enforce any provision of
this Section 3.7(b).

          (c) Notwithstanding anything herein to the contrary, but subject to the prior payment of funds
pursuant to Section 3.4, so long as no Event of Default shall have occurred and be continuing, the
Calculation Agent shall, on the 15th day of each calendar month (other than any month in which a
Payment Date falls), reimburse and pay to the Issuer (or such other appropriate Person identified
at the written instruction of the Issuer), from the Collection Account, an amount equal to the
lesser of (i) all Expenses not previously paid or reimbursed and (ii) the balance of the Collection
Account, in either case upon delivery to the Calculation Agent by the Issuer, not less than three
Business Days prior to such 15th day, of supporting documentation therefor in writing.

          (d) Notwithstanding anything herein to the contrary, the priority of payments set forth in
Section 3.7(a) shall be adjusted to give effect to (i) any inaccuracy set forth in any report of an
accounting firm pursuant to Section 6.14(b), such that each Person shall be restored on the
immediately succeeding Payment Date (or, if necessary, the immediately succeeding Payment Dates) to
the cash flow position that such Person would have been in had the accurate amounts
set forth in such report been paid in accordance with Section 3.7(a) on the relevant prior
Payment Dates, and (ii) the amount by which any Audit Expenses exceed $20,000 per annum (to the
extent that such excess amount is to be borne by the Noteholders in accordance with Section
6.14(b)), such that any payments to the Noteholders pursuant to Section 3.7(a) shall first be
offset against the payment of such Audit Expenses; provided, that the Issuer (or the
Servicer) shall notify the Trustee in writing of the occurrence of the events described in the
proviso to Section 6.14 and an itemization of the impact on the cash flows pursuant to Section
3.7(a).

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          (e) To the extent that any monies are deposited in the Collection Account to reimburse prior
distributions in respect of a Seller Shortfall, such monies shall be paid to the Trustee on behalf
of the Noteholders before making any other distributions pursuant to Section 3.7(a) to the extent
that such monies otherwise would have been paid to such Noteholders on the prior respective Payment
Date in accordance with this Section 3.7 in the absence of such Seller Shortfall.

     Section 3.8
Interest Reserve Account and Capital Account; Interest Shortfalls. If the Calculation
Agent has determined that an Interest Shortfall exists pursuant to the Calculation Report with
respect to any Payment Date and there is a positive balance in the Interest Reserve Account on the
Relevant Calculation Date immediately preceding such Payment Date, then on such Payment Date the
Trustee shall withdraw from the Interest Reserve Account an amount equal to the lesser of the
Interest Shortfall and the balance in the Interest Reserve Account and distribute it to the
Noteholders of the Class A Notes in payment of the Interest Amount; provided, that, if the
amount available in the Interest Reserve Account (if any) is less than the amount of such Interest
Shortfall and there is a positive balance in the Capital Account on the Relevant Calculation Date
immediately preceding such Payment Date, then on such Payment Date the Trustee shall, if directed
in writing by the Issuer and the Seller, withdraw from the Capital Account an amount equal to the
lesser of (i) the amount by which the Interest Shortfall exceeds the amount, if any, withdrawn from
the Interest Reserve Account and (ii) the balance in the Capital Account and distribute it to the
Noteholders of the Class A Notes in payment of the Interest Amount; provided,
further, that the Trustee shall (a) make such a withdrawal from the Capital Account only
once, whether in respect of such Payment Date or on any other Business Day, and (b) distribute any
funds remaining in the Capital Account to the Equityholders upon their written request in the event
that such one-time withdrawal from the Capital Account has been made. If funds from the Interest
Reserve Account and the Capital Account are insufficient or otherwise not made available to pay the
remaining Interest Shortfall, then the unpaid Interest Shortfall shall accrue interest at the
interest rate applicable to the Class A Notes compounded annually. If such unpaid Interest
Shortfall (and interest thereon) in the case of any Payment Date other than the Final Legal
Maturity Date is not paid in full on or prior to the next succeeding Payment Date following the
Payment Date on which such interest was first payable, an Event of Default shall occur on such next
succeeding Payment Date (but not before such date). Notwithstanding the foregoing, if, on the
Final Legal Maturity Date, (x) the portion of the Available Collections Amount available to pay in
full the Outstanding Principal Balance on the Class A Notes, after giving effect to the other
payments to be made on the Final Legal Maturity Date and entitled to priority pursuant to Section
3.7, are insufficient to pay in full the Outstanding Principal Balance on the Class A Notes, and
(y) there is a positive balance in the Capital Account after giving effect to any withdrawal
therefrom in respect of any Interest
Shortfall, then on the Final Legal Maturity Date the Trustee shall withdraw from the Capital
Account an amount equal to the lesser of the Outstanding Principal Balance on the Class A Notes and
the balance of the Capital Account and distribute it to the Noteholders of the Class A Notes for
payment of all or any portion of the Outstanding Principal Balance on the Class A Notes.

     From and including the September 1, 2014 Payment Date to and including the September 1, 2016
Payment Date, if no Event of Default has occurred and is continuing, the Issuer may, at its option
upon written direction to the Trustee on or prior to the related Calculation Date, replenish the
Interest Reserve Account from time to time from the Available Collections Amount

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on such Payment
Date (after the payment of the amounts described in Section 3.4, Section 3.7(a)(i), Section
3.7(a)(ii) and Section 3.7(a)(iii)); provided, however, that all such
replenishments (if any) taken together shall not exceed $2,100,000 in the aggregate.

     On each of the September 1, 2013 Payment Date and the September 1, 2017 Payment Date, any
funds remaining in the Interest Reserve Account (after any application of the first paragraph of
this Section 3.8 on such September 1, 2013 Payment Date or September 1, 2017 Payment Date, as the
case may be) shall be transferred to the Collection Account and included in the Available
Collections Amount and applied as provided in Section 3.7 on such September 1, 2013 Payment Date or
September 1, 2017 Payment Date, as the case may be.

     Section 3.9 Redemptions.

          (a) On any Redemption Date, the Trustee shall distribute the amounts in the applicable
Redemption Account as provided herein and in the applicable Resolution, including:

          (i) to the extent Subordinated Notes or Refinancing Notes were issued for the purpose
of funding such Redemption, paying to such Persons as shall be specified by the Issuer such
Transaction Expenses as shall be due and payable in connection with the issuance and sale of
the applicable Subordinated Notes or Refinancing Notes;

          (ii) remitting to the Noteholders of such class of Notes, in accordance with the
Resolution authorizing such Redemption (and, if such Redemption Date is a Payment Date,
after application of Section 3.7 and Section 3.8), an amount equal to the Redemption Price
plus Premium, if any, allocated, in the event of a Redemption of such Notes in part, pro
rata in proportion to the Outstanding Principal Balance of such Notes held by such
Noteholders; and

          (iii) making such other distributions and payments as shall be authorized and directed
by the Resolution and indentures supplemental hereto executed in connection with such
Redemption.

          (b) Subject to the provisions of Section 3.9(c) and Section 3.10, on any Redemption Date (and,
if such Redemption Date is a Payment Date, to the extent that any class of Notes will remain
Outstanding after application of Section 3.7 and Section 3.8), the Issuer may elect to redeem such
class of Notes, in whole, but not in part, out of the proceeds of any Refinancing Notes and any
funds in the Interest Reserve Account in the case of a Refinancing of such class of Notes, or, in
whole or in part, out of amounts available in the Capital Account or the Redemption Account for
such purpose, if any, including the proceeds of any Subordinated
Notes (but excluding in the case of a Redemption in part any funds in the Interest Reserve
Account, except for any payment in respect thereof representing interest payable in connection with
the Redemption), in each case, at the Redemption Price (any such redemption, an “Optional
Redemption”). The Issuer shall give written notice of any such Optional Redemption to the
Trustee and the Servicer not later than five Business Days prior to the date on which notice is to
be given to Noteholders in accordance with Section 3.10(a) (unless the Trustee and any such
Servicer agree to waive or limit the requirement for such notice). Such written notice to the
Trustee shall include a copy of the Resolution authorizing such Optional Redemption and shall

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set
forth the relevant information regarding such Optional Redemption, including the information to be
included in the notice given pursuant to Section 3.10(a).

          (c) An indenture supplemental hereto providing for the issuance of any Subordinated Notes or
Refinancing Notes may authorize one or more redemptions, in whole or in part, of such Notes, on
such terms and subject to such conditions as shall be specified in such indenture supplemental
hereto; provided, that, while any Class A Notes are Outstanding, such Subordinated Notes
may only be redeemed by the Issuer with proceeds from Refinancing Notes in respect of such
Subordinated Notes or capital contributions from the Equityholders.

          (d) The application of Royalties or Currency Hedge Payments to principal payments on any Notes
shall not be deemed to be a redemption or partial redemption of such Notes.

     Section 3.10 Procedure for Redemptions.

          (a) The Trustee (or the Servicer acting as its agent (or any authorized agent of any such
Servicer)) shall give written notice in respect of any Redemption of any class of Notes under
Section 3.9 to each Noteholder of such Notes at least 30 days but not more than 60 days before such
Redemption Date. Each notice in respect of a Redemption given pursuant to this Section 3.10(a)
shall state (A) the expected applicable Redemption Date, (B) the arrangements for making payments
in respect of such Redemption, (C) the projected Redemption Price of the Notes to be redeemed, (D)
in the case of a Redemption of the Notes of any class in part, the portion of the Outstanding
Principal Balance of the Notes that is expected to be redeemed, (E) that Notes to be redeemed in a
Redemption in whole must be surrendered (which action may be taken by any Noteholder or its
authorized agent) to the Trustee to collect the Redemption Price on such Notes and (F) that, unless
the Issuer fails to pay the Redemption Price, interest on Notes called for Redemption in whole
shall cease to accrue on and after the Redemption Date. If mailed in the manner herein provided,
the notice shall be conclusively presumed to have been given whether or not the Noteholder receives
such notice.

          (b) If, at the time of the mailing of any notice in respect of a Redemption, the Issuer shall
not have irrevocably directed the Trustee to apply funds then on deposit with the Trustee or held
by the Issuer and available to be used for such Redemption to redeem all of the Notes called for
Redemption, such notice, at the election of the Issuer, may state that such Redemption is
conditional and subject to the receipt of the redemption moneys in an amount sufficient to pay the
principal of and Premium, if any, and interest on the Notes being redeemed and related Transaction
Expenses by the Trustee on or before the Redemption Date and that such
notice shall be of no force and effect, and the Issuer shall not be required to redeem such
Notes, unless such Redemption moneys are so received on or before such Redemption Date.

          (c) If notice in respect of a Redemption for any Notes shall have been given as provided in
Section 3.10(a) and such notice shall not contain the language permitted at the Issuer’s option
under Section 3.10(b), such Notes shall become due and payable on the Redemption Date at the
Corporate Trust Office at the applicable Redemption Price, and, unless there is a default in the
payment of the applicable Redemption Price, interest on such Notes shall cease to accrue on and
after the Redemption Date. Upon presentation and surrender of such

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Notes at the Corporate Trust
Office, such Notes shall be paid and redeemed at the applicable Redemption Price. On or before any
Redemption Date in respect of such a Redemption, the Issuer shall, to the extent an amount equal to
the Redemption Price of such Notes (and any Transaction Expenses relating thereto as of the
Redemption Date) is not then held by the Issuer or on deposit in the Redemption Account, deposit or
cause to be deposited in the Redemption Account an amount in immediately available funds so that
the total amount in the Redemption Account shall be sufficient to pay such Redemption Price (and
any Transaction Expenses relating thereto as of the Redemption Date).

          (d) If notice in respect of a Redemption for any Notes shall have been given as provided in
Section 3.10(a) and such notice shall contain the language permitted at the Issuer’s option under
Section 3.10(b), such Notes shall become due and payable on the Redemption Date at the Corporate
Trust Office at the applicable Redemption Price and interest on such Notes shall cease to accrue on
and after the Redemption Date; provided, that, in each case, the Issuer shall have
deposited in the Redemption Account on or prior to 11:00 a.m. (New York City time) on the
Redemption Date an amount sufficient to pay the Redemption Price (and any Transaction Expenses
relating thereto as of the Redemption Date). Upon the Issuer making such deposit and presentation
and surrender of such Notes at the Corporate Trust Office, such Notes shall be paid and redeemed at
the applicable Redemption Price. If the Issuer shall not make such deposit on or prior to 11:00
a.m. (New York City time) on the Redemption Date, the notice in respect of Redemption shall be of
no force and effect, and the principal on such Notes or specified portions thereof shall continue
to bear interest as if such notice in respect of Redemption had not been given.

          (e) All Notes that are redeemed will be surrendered to the Trustee for cancellation and may
not be reissued or resold.

     Section 3.11 Seller Shortfall. If, no later than ten Business Days prior to any Calculation Date,
the Trustee receives written notice of the existence of a Seller Shortfall, the Trustee shall
promptly (but in no event later than the next succeeding Business Day following receipt of such
written notice) notify the Servicer, the Seller and the Issuer of such existence of a Seller
Shortfall. Upon the Issuer or the Seller receiving notification of the same, or upon the Issuer or
the Seller otherwise becoming aware of a Seller Shortfall, the Issuer shall cause the Servicer, no
later than such Calculation Date, to confirm the amount of any such Seller Shortfall in writing to
the Trustee, with a copy to the Issuer and the Seller. Unless the Trustee shall have received
prior to the related Payment Date (i) written notification from the Seller or the Servicer
certifying that any such Seller
Shortfall has been cured in full or (ii) written notice from at least two-thirds of the
Outstanding Principal Balance of the Senior Class of Notes that such payment shall not be made on
such Payment Date, then prior to making any other distributions pursuant to Section 3.7 or Section
3.8, the Trustee shall make a Seller Shortfall Payment to Counterparty or the Currency Hedge
Provider, as the case may be, on such Payment Date in the amount of such Seller Shortfall from the
Collection Account; provided, that if Counterparty or the Currency Hedge Provider, as the
case may be, shall refuse to accept such payment, then such funds shall be returned to the
Collection Account for distribution in accordance with this Indenture on the first possible Payment
Date. The Trustee shall have no duty under this Section 3.11 to determine whether a Seller
Shortfall exists, and the Trustee may assume that no Seller Shortfall has occurred until and unless
the Trustee receives written notice thereof. The Trustee is not a party

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to and has no duties with
respect to the Counterparty License Agreement or the Currency Hedge Agreement.

     Section 3.12 Currency Exchange.

          (a) Yen accumulated in the Collection Account as of 10:00 a.m., New York City time, on May 18
of any year (if such date is the expiration date of an Option), in an amount of yen equal to the
lesser of (i) the amount of yen then accumulated in the Collection Account and (ii) an amount of
yen equal to the notional amount of yen covered by such Option, shall be exchanged by the Issuer
into dollars at such time to the extent that the yen-dollar foreign currency exchange spot rate at
such time is $1£¥100 (provided, however, that the Issuer, in its discretion, may exchange a greater
amount of yen on such date in its sole discretion). Such currency exchange shall be effected
through the Currency Hedge Provider or an affiliate thereof in one or more foreign currency
exchange spot market transactions at the then-prevailing yen-dollar foreign currency exchange spot
rate. To the extent such date is the expiration date of an Option and the yen-dollar foreign
currency exchange spot rate at such time is $1>¥100, the Issuer shall exchange yen for dollars
through the physical settlement of such Option with respect to an amount of yen equal to the lesser
of (A) the amount of yen then accumulated in the Collection Account and (B) an amount of yen equal
to the notional amount of yen covered by such Option. Notwithstanding anything in the immediately
preceding sentences of this Section 3.12(a) to the contrary, the Issuer shall not be required to
exchange yen for dollars pursuant to the first or third sentence of this Section 3.12(a) on any May
18 that is an expiration date of an Option (whether or not the yen-dollar foreign currency exchange
spot rate as of 10:00 a.m., New York City time, on such May 18 is $1£¥100) in an amount that is
greater than, and the Issuer’s obligation to exchange yen for dollars pursuant to such first or
third sentence of this Section 3.12(a) shall be limited to, that amount of yen determined by
subtracting (x) the amount of yen, if any, exchanged by the Issuer pursuant to Section 3.12(c)
subsequent to the immediately preceding Calculation Date and prior to such May 18 from (y) the
notional amount of yen with respect to such May 18 covered by such Option; provided, however, that
the Issuer, in its discretion, may exchange a greater amount of yen on such date to the extent that
such exchange otherwise complies with the provisions of Section 3.12(c) (without regard to the
provisions limiting the effect of Section 3.12(c) to any Business Day other than the expiration
date of an Option or another date on which the Issuer is required to effect an exchange of yen for
dollars as described in this Section 3.12(a) or Section 3.12(b)). For the avoidance of doubt, if
any May 18 is not the expiration date of an Option, the Issuer shall not be required to exchange
yen in the Collection Account on such date for dollars pursuant to this Section 3.12(a) (even if
the then-current yen-dollar foreign currency exchange spot rate is $1£¥100); provided,
however, that, in
such case, the Issuer may, in its sole discretion, elect to exchange yen for dollars to the
extent otherwise permitted on such date in accordance with Section 3.12(c).

          (b) All yen accumulated in the Collection Account as of 10:00 a.m., New York City time, on
August 18 of any year or on November 18, 2020 shall be exchanged by the Issuer into dollars at such
time, regardless of the then-prevailing yen-dollar foreign currency exchange spot rate or whether
or not such date is the expiration date of an Option. Such currency exchanges shall take place in
a foreign currency exchange spot market transaction at the then-prevailing foreign currency
exchange spot rate through the Currency Hedge Provider or an

41

 

affiliate thereof and/or, if such date
is also the expiration date of an Option, through physical settlement by the Currency Hedge
Provider of such Option (or a portion thereof).

          (c) On any Business Day other than the expiration date of an Option or another date on which
the Issuer is required to effect an exchange of yen for dollars as described in Section 3.12(a) or
Section 3.12(b), the Issuer shall have the right (but not the obligation), in its discretion, to
effect foreign currency exchange spot market transactions through the Currency Hedge Provider or an
affiliate thereof in order to exchange all or a portion of the yen then accumulated in the
Collection Account for dollars at the then-current yen-dollar foreign currency exchange spot rate;
provided, that, at such time, such yen-dollar foreign currency exchange spot rate is
$1£¥100.

          (d) To the extent any date on which the Issuer is required to exchange yen for dollars is a
day that is not a Business Day, such currency exchange will not be required to be effected until
the next succeeding Business Day.

          (e) Notwithstanding anything in this Section 3.12 to the contrary, any currency exchange
contemplated by this Section 3.12 may be effected through a Person other than the Currency Hedge
Provider or an affiliate thereof in the event of a material breach of the Currency Hedge Agreement
by the Currency Hedge Provider.

          (f) Any foreign currency exchange transaction under this Section 3.12 shall occur upon written
direction from the Issuer to the Trustee designating the amount of yen for exchange and providing
wire instructions for delivery of such yen. Upon such written direction, the Trustee shall make
such withdrawals from the Collection Account, and accept such deposits into the Collection Account,
and otherwise reasonably cooperate with the Issuer, to facilitate such foreign currency exchange
transactions. The Trustee shall have no duties under this Section 3.12 other than to follow such
written direction of the Issuer with respect to delivery of yen for exchange to dollars. Without
limitation of the foregoing, the Trustee shall have no duty to monitor Option expiration dates or
yen-dollar foreign currency exchange spot rates, whether absolutely or relative to dollars.

ARTICLE IV

DEFAULT AND REMEDIES

     
Section 4.1 Events of Default. Each of the following events or occurrences shall constitute an “Event of Default”
hereunder with respect to any class of Notes (except for clauses (a), (b), (c) and (d) below in
which the potential events or occurrences that would constitute an Event of Default are specific to
certain classes of Notes, in which case such Event of Default shall be constituted only with
respect to such classes of Notes (and not all classes of Notes)), and each such Event of Default
shall be deemed to exist and continue so long as, but only so long as, it shall not have been
waived or remedied, as applicable:

          (a) (i) failure to pay interest on the Class A Notes due on any Payment Date (other than the
Final Legal Maturity Date or any Redemption Date) within five Business Days of such Payment Date,
but only to the extent of the Available Collections Amount available for interest payments pursuant
to the priority of payments in Section 3.7, any funds in the Interest

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Reserve Account and any
capital contributed to the Issuer by the Equityholders as described in Section 3.1(f) and available
for interest payments pursuant to Section 3.8, or (ii) failure to pay principal of the Class A
Notes due on any Payment Date (other than the Final Legal Maturity Date or any Redemption Date)
within five Business Days of such Payment Date, but only to the extent of the Available Collections
Amount available for principal payments pursuant to the priority of payments in Section 3.7;

          (b) (i) failure to pay interest on the Class A Notes due on any Payment Date (other than the
Final Legal Maturity Date or any Redemption Date or as set forth in Section 4.1(a)) in full on or
prior to the next succeeding Payment Date, together with Additional Interest on any interest not
paid on the Payment Date on which it was originally due, and (ii) in the case of any class of Notes
other than the Class A Notes, except as provided in the related Resolution and set forth in any
indenture supplemental hereto providing for the issuance of such Notes pursuant to Section 2.15 or
Section 2.16, failure to pay interest on any Notes of such class within 30 days of the Payment Date
on which such interest is due (or, in the case of the Final Legal Maturity Date or any Redemption
Date with respect to such class of Notes, on such Final Legal Maturity Date or such Redemption
Date, as the case may be), in each case regardless of whether or not funds are then available
therefor in the Collection Account;

          (c) (i) failure to pay principal of and Premium, if any, and accrued and unpaid interest on
any Notes of such class on the applicable Final Legal Maturity Date or (ii) if all conditions to
the Redemption have been satisfied and subject to Section 3.10(b), failure to pay the Redemption
Price when due on any Redemption Date for such class;

          (d) failure to pay any other amount in respect of the Notes when due and payable in connection
with such class of Notes and the continuance of such default for a period of 30 or more days after
written notice thereof is given to the Issuer by the Trustee;

          (e) failure by the Issuer to comply with any covenant, obligation, condition or provision
binding on it under this Indenture or the Notes (other than a payment default for which provision
is made in Section 4.1(a), Section 4.1(b), Section 4.1(c) or Section 4.1(d)); provided,
that, (i) if the consequences of the failure can be cured, such failure continues for a period of
30 days or more after written notice thereof has been given to the Issuer by the Trustee at the
Direction of Noteholders of a majority of the Outstanding Principal Balance of the Senior Class
of Notes, and (ii) except in respect of a covenant, obligation, condition or provision already
qualified in respect of Material Adverse Change, such failure is a Material Adverse Change;

          (f) the Issuer becomes subject to a Voluntary Bankruptcy or an Involuntary Bankruptcy;

          (g) any judgment or order for the payment of money in excess of $1,000,000 (not paid or
covered by insurance) shall be rendered against the Issuer and either (i) enforcement proceedings
have been commenced by any creditor upon such judgment or order or (ii) there is any period of 30
consecutive days during which a stay of enforcement of such judgment or order, by reason of a
pending appeal or otherwise, shall not be in effect;

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          (h) the Issuer becomes an investment company required to be registered under the
Investment Company Act of 1940, as amended;

          (i) the Issuer is classified as a corporation or publicly traded partnership taxable as a
corporation for U.S. federal income tax purposes;

          (j) the Seller shall have failed to perform any of its covenants under the Purchase and
Sale Agreement where such failure is a Material Adverse Change;

          (k) the Equityholders shall have failed to perform any of their covenants under the Pledge
and Security Agreement where such failure is a Material Adverse Change; or

          (l) the Trustee shall fail to have a first-priority perfected security interest in any of
the Collateral, in any of the Issuer Pledged Equity or in any material portion of the other Issuer
Pledged Collateral.

     Section 4.2 Acceleration, Rescission and Annulment.

          (a) If an Event of Default with respect to the Notes (other than an Acceleration Default)
occurs and is continuing, the Senior Trustee may, and, upon the Direction of Noteholders of a
majority of the Outstanding Principal Balance of the Senior Class of Notes, shall, give an
Acceleration Notice to the Issuer. Upon delivery of such an Acceleration Notice (and so long as
such Acceleration Notice has not been rescinded and annulled pursuant to this Indenture), the
Outstanding Principal Balance of the Notes and all accrued and unpaid interest thereon shall be
immediately due and payable. At any time after the Senior Trustee or such Noteholders have so
declared the Outstanding Principal Balance of the Notes to be immediately due and payable, and
prior to the exercise of any other remedies pursuant to this Article IV, the Senior Trustee, upon
the Direction of Noteholders of a majority of the Outstanding Principal Balance of the Senior Class
of Notes, shall, subject to Section 4.5(a), by written notice to the Issuer, rescind and annul such
declaration and thereby annul its consequences if (i) there has been paid to or deposited with the
Trustee an amount sufficient to pay all overdue installments of interest on the Notes, and the
principal of, and Premium, if any, on, the Notes that would have become due otherwise than by such
declaration of acceleration, (ii) the rescission would not conflict with any judgment or decree and
(iii) all other Defaults and Events of Default, other than non-payment of interest and Premium, if
any, on and principal of the Notes that have become due solely because of such declaration of
acceleration, have been cured or waived. If an Acceleration Default occurs, the Outstanding
Principal Balance of the Notes and all accrued and unpaid interest thereon shall automatically
become immediately due and payable without any further action by any party.

          (b) Notwithstanding this Section 4.2, Section 4.3 and Section 4.12, after the occurrence
and during the continuation of an Event of Default, no Noteholders of any class of Notes other than
the Senior Class of Notes shall be permitted to give or direct the giving of an Acceleration
Notice, or to exercise any remedy in respect of such Event of Default, and no Person other than the
Senior Trustee, at the Direction of Noteholders of a majority of the Outstanding Principal Balance
of the Senior Class of Notes, may give an Acceleration Notice or exercise any such remedy.

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          (c) Within 30 days after the occurrence of an Event of Default in respect of any class of
Notes, the Trustee shall give to the Noteholders notice, transmitted by mail, of all uncured or
unwaived Defaults known to it on such date; provided, that the Trustee may withhold such
notice with respect to a Default (other than a payment default with respect to interest, principal
or Premium, if any) if it determines in good faith that withholding such notice is in the interest
of the affected Noteholders.

     Section 4.3 Other Remedies. Subject to the provisions of this Indenture and the Pledge and
Security Agreement, if an Event of Default shall have occurred and be continuing, then the Senior
Trustee may, but only at the Direction of Noteholders of a majority of the Outstanding Principal
Balance of the Senior Class of Notes, pursue any available remedy by proceeding at law or in equity
to collect the payment of principal, Premium, if any, or interest due on the Notes or to enforce
the performance of any provision of the Notes, this Indenture, the Servicing Agreement, the Pledge
and Security Agreement or the Currency Hedge Agreement, including any of the following, to the
fullest extent permitted by law, subject to the receipt of such Direction:

          (a) The Senior Trustee may obtain the appointment of a Receiver of the Indenture Estate as
provided in Section 12.7 and the Issuer consents to and waives any right to notice of any such
appointment.

          (b) The Senior Trustee may, without notice to the Issuer and at such time as the Senior
Trustee in its sole discretion may determine, exercise any or all of the Issuer’s rights in, to and
under or in any way connected with or related to any or all of the Indenture Estate, including (i)
demanding and enforcing payment and performance of, and exercising any or all of the Issuer’s
rights and remedies with respect to the collection, enforcement or prosecution of, any or all of
the Indenture Estate (including the Purchased Assets and the Issuer’s rights under the Purchase and
Sale Agreement), in each case by legal proceedings or otherwise, (ii) settling, adjusting,
compromising, extending, renewing, discharging and releasing any or all of, and any legal
proceedings brought to collect or enforce any or all of, the Purchased Assets and otherwise under
the Deal Documents and (iii) preparing, filing and signing the name of the Issuer on (A) any proof
of claim or similar document to be filed in any bankruptcy or similar proceeding involving the
Indenture Estate (including the Purchased Assets) and (B) any notice of lien, assignment or
satisfaction of lien, or similar document in connection with the Indenture Estate (including the
Purchased Assets).

          (c) Subject to the Pledge and Security Agreement (including the provisions of Section 11.1
of the Pledge and Security Agreement), the Senior Trustee may, without notice except as specified
herein, and as required by Applicable Law, in accordance with Applicable Law, sell or cause the
sale of all or any part of the Indenture Estate in one or more parcels at public or private sale,
at any of the Senior Trustee’s offices or elsewhere, for cash, on credit or for future delivery,
and upon such other terms as the Senior Trustee may deem commercially reasonable, provided,
that, so long as the Counterparty License Agreement remains in force, the Senior Trustee shall make
any such sale only to a Person that is a Permitted Holder. The Issuer agrees that, to the extent
notice of sale shall be required by law, at least ten days’ notice to the Issuer of the time and
place of any public sale or the time after which any private sale is to be
made shall constitute reasonable notification. The Senior Trustee shall not be obligated to
make

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any sale of all or any part of the Indenture Estate regardless of notice of sale having been
given. The Senior Trustee may adjourn any public or private sale from time to time by announcement
at the time and place fixed therefor, and such sale may, without further notice, be made at the
time and place to which it was so adjourned.

          (d) The Senior Trustee may, instead of exercising the power of sale conferred upon it by
Section 4.3(c) and Applicable Law, proceed by a suit or suits at law or in equity to foreclose the
Security Interest and sell all or any portion of the Indenture Estate under a judgment or a decree
of a court or courts of competent jurisdiction, provided, that, so long as the Counterparty
License Agreement remains in force, the Senior Trustee shall make any such foreclosure sale only to
a Person that is a Permitted Holder.

          (e) The Senior Trustee may require the Issuer to, and the Issuer hereby agrees that it
shall at its expense and upon request of the Senior Trustee, forthwith assemble all or part of the
Indenture Estate as directed by the Senior Trustee and make it available to the Senior Trustee at a
place to be designated by the Senior Trustee that is reasonably convenient to both parties.

          (f) In addition to the rights and remedies provided for in this Indenture, the Senior
Trustee may exercise in respect of the Indenture Estate all the rights and remedies of a secured
party upon default under the UCC (whether or not the UCC applies to the affected property included
in the Indenture Estate) and under all other Applicable Law; provided, that, so long as the
Counterparty License Agreement remains in force, the Senior Trustee shall cause any sale of the
Collateral to be made only to a Person that is a Permitted Holder.

          (g) The Senior Trustee may maintain a proceeding even if it does not possess any of the
Notes or does not produce any of them in the proceeding.

     Section 4.4 Limitation on Suits. Without limiting the provisions of Section 4.9 and the final
sentence of Section 12.4, no Noteholder shall have any right to institute any proceeding, judicial
or otherwise, with respect to this Indenture, the Pledge and Security Agreement or the Notes, for
the appointment of a receiver or trustee or for any other remedy hereunder, unless:

          (a) such Noteholder is a holder of the Senior Class of Notes and has previously given
written notice to the Senior Trustee of a continuing Event of Default;

          (b) the Noteholders of a majority of the Outstanding Principal Balance of the Senior Class
of Notes make a written request to the Senior Trustee to pursue a remedy hereunder;

          (c) such Noteholder or Noteholders offer to the Senior Trustee an indemnity reasonably
satisfactory to the Senior Trustee against any costs, expenses and liabilities to be incurred in
complying with such request;

          (d) the Senior Trustee does not comply with such request within 60 days after receipt of
the request and the offer of indemnity; and

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          (e) during such 60-day period, Noteholders of a majority of the Outstanding Principal
Balance of the Senior Class of Notes do not give the Senior Trustee a Direction inconsistent with
such request.

     No one or more Noteholders may use this Indenture to affect, disturb or prejudice the rights
of another Noteholder or to obtain or seek to obtain any preference or priority not otherwise
created by this Indenture and the terms of the Notes over any other Noteholder or to enforce any
right under this Indenture, except in the manner herein provided.

     Section 4.5 Waiver of Existing Defaults.

          (a) The Senior Trustee, upon the Direction of Noteholders of a majority of the Outstanding
Principal Balance of the Senior Class of Notes, by written notice to the Issuer may waive any
existing Default (or Event of Default) hereunder and its consequences, except a Default (or Event
of Default) (i) in the payment of the interest on, principal of and Premium, if any, on any Note or
(ii) in respect of a covenant or provision hereof that under Article IX cannot be modified or
amended without the consent of the Noteholder of each Note affected thereby. Upon any such waiver,
such Default shall cease to exist, and any Event of Default arising therefrom shall be deemed to
have been cured for every purpose of this Indenture, but no such waiver shall extend to any
subsequent or other Default (or Event of Default) or impair any right consequent thereon.

          (b) Any written waiver of a Default or an Event of Default given by the Senior Trustee to
the Issuer in accordance with the terms of this Indenture shall be binding upon the Senior Trustee
and the other parties hereto. Unless such writing expressly provides to the contrary, any waiver
so granted shall extend only to the specific event or occurrence that gave rise to the Default or
Event of Default so waived and not to any other similar event or occurrence that occurs subsequent
to the date of such waiver.

     Section 4.6 Restoration of Rights and Remedies. If the Senior Trustee or any Noteholder of the
Senior Class of Notes has instituted any proceeding to enforce any right or remedy under this
Indenture, and such proceeding has been discontinued or abandoned for any reason or has been
determined adversely to the Senior Trustee or such Noteholder, then in every such case the Issuer,
the Senior Trustee and the Noteholders shall, subject to any determination in such proceeding, be
restored severally and respectively to their former positions hereunder, and thereafter all rights
and remedies of the Senior Trustee and the Noteholders shall continue as though no such proceeding
has been instituted.

     Section 4.7 Remedies Cumulative. Each and every right, power and remedy herein given to the
Trustee specifically or otherwise in this Indenture shall be cumulative and shall, to the extent
permitted by law, be in addition to every other right, power and remedy herein specifically given
or now or hereafter existing at law, in equity or by statute, and each and every right, power and
remedy whether
specifically herein given or otherwise existing may be exercised from time to time and as
often and in such order as may be deemed expedient by the Trustee, and the exercise or the
beginning of the exercise of any power or remedy shall not be construed to be a waiver of the right
to exercise at the same time or thereafter any other right, power or remedy. No delay or omission
by the Trustee in the exercise of any right, remedy or

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power or in the pursuance of any remedy
shall impair any such right, power or remedy or be construed to be a waiver of any Default on the
part of the Issuer or to be an acquiescence.

     Section 4.8 Authority of Courts Not Required. The parties hereto agree that, to the greatest
extent permitted by law, the Trustee shall not be obliged or required to seek or obtain the
authority of, or any judgment or order of, the courts of any jurisdiction in order to exercise any
of its rights, powers and remedies under this Indenture, and the parties hereby waive any such
requirement to the greatest extent permitted by law.

     Section 4.9 Rights of Noteholders to Receive Payment. Notwithstanding any other provision of this
Indenture, the right of any Noteholder to receive payment of interest on, principal of, or Premium,
if any, on any Note on or after the respective due dates therefor expressed in such Note, or to
bring suit for the enforcement of any such payment on or after such respective dates, shall not be
impaired or affected without the consent of such Noteholder.

     Section 4.10 Trustee May File Proofs of Claim. The Trustee may file such proofs of claim and other
papers or documents as may be necessary or advisable in order to have the claims of the Trustee and
of any Noteholder allowed in any judicial proceedings relating to any obligor on the Notes, its
creditors or its property.

     Section 4.11 Undertaking for Costs. All parties to this Indenture agree, and each Noteholder by
its acceptance hereof shall be deemed to have agreed, that, in any suit for the enforcement of any
right or remedy under this Indenture or in any suit against the Trustee for any action taken or
omitted by it as Trustee, a court in its discretion may require the filing by any party litigant in
such suit of an undertaking to pay the costs of such suit, and the court in its discretion may
assess reasonable costs, including reasonable attorneys’ fees, against any party litigant in such
suit, having due regard to the merits and good faith of the claims or defense made by the party
litigant. This Section 4.11 does not apply to a suit instituted by the Trustee, a suit instituted
by any Noteholder for the enforcement of the payment of interest, principal, or Premium, if any, on
any Note on or after the respective due dates expressed in such Note or a suit by a Noteholder or
Noteholders of at least 10% of the Outstanding Principal Balance of the Notes.

     Section 4.12 Control by Noteholders. Subject to this Article IV and to the rights of the Trustee
hereunder, Noteholders of a majority of the Outstanding Principal Balance of the Notes shall have
the right to direct the time,
method and place of conducting any proceeding for any remedy available to the Trustee or
exercising any trust, right or power conferred on the Trustee under any Transaction Document;
provided, that:

          (a) such Direction shall not be in conflict with any rule of law or with this Indenture
and would not involve the Trustee in personal liability or expense;

          (b) the Trustee shall not determine that the action so directed would be unjustly
prejudicial to the Noteholders of such class not taking part in such Direction; and

          (c) the Trustee may take any other action deemed proper by the Trustee that is not
inconsistent with such Direction.

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     Section 4.13 Senior Trustee. The Trustee irrevocably agrees (and the Noteholders (other than the
Noteholders represented by the Senior Trustee) shall be deemed to agree by virtue of their purchase
of the Notes) that the Senior Trustee shall have all of the rights granted to it under this
Indenture, including the right to direct the Trustee to take certain action as provided for in this
Indenture, and the Trustee hereby agrees to act in accordance with each such authorized direction
of the Senior Trustee.

     Section 4.14 Application of Proceeds. All cash proceeds received by the Senior Trustee in respect
of any sale of, collection from or other realization upon all or any part of the Indenture Estate
shall be deposited in the Collection Account and distributed as provided in Article III. Any
surplus of such cash proceeds held and remaining after payment in full of all Secured Obligations
shall be paid over to the Issuer or whomsoever may be lawfully entitled to receive such surplus as
provided in Section 3.7. Any amount received for any sale or sales conducted in accordance with
the terms of Section 4.3 shall to the extent permitted by Applicable Law be deemed conclusive and
binding on the Issuer and the Noteholders.

     Section 4.15 Waivers of Rights Inhibiting Enforcement. The Issuer waives (a) any claim that, as to
any part of the Indenture Estate, a private or public sale, should the Senior Trustee elect so to
proceed, is, in and of itself, not a commercially reasonable method of sale for such part of the
Indenture Estate, (b) except as otherwise provided in any of the Deal Documents, TO THE EXTENT
PERMITTED BY APPLICABLE LAW, NOTICE OR JUDICIAL HEARING IN CONNECTION WITH THE TRUSTEE’S TAKING
POSSESSION OR DISPOSITION OF ANY OF THE INDENTURE ESTATE, INCLUDING ANY AND ALL PRIOR NOTICE AND
HEARING FOR ANY PREJUDGMENT REMEDY OR REMEDIES AND ANY SUCH RIGHT THAT THE ISSUER WOULD OTHERWISE
HAVE UNDER THE CONSTITUTION OR ANY STATUTE OF THE U.S. OR OF ANY STATE, AND ALL OTHER REQUIREMENTS
AS TO THE TIME, PLACE AND TERMS OF SALE OR OTHER REQUIREMENTS WITH RESPECT TO THE ENFORCEMENT OF
THE TRUSTEE’S RIGHTS HEREUNDER, (c) all rights of redemption, appraisement, valuation, stay and
extension or moratorium and (d) except as otherwise provided in any of the Deal Documents
(including Section 11.1 of the Pledge and Security Agreement), all other rights the exercise
of which would, directly or indirectly, prevent, delay or inhibit the enforcement of any of the
rights or remedies under this Indenture or the absolute sale of the Indenture Estate, now or
hereafter in force under any Applicable Law, and the Issuer, for itself and all who may claim under
it, insofar as it or they now or hereafter lawfully may, hereby waives the benefit of all such laws
and rights.

     Section 4.16 Security Interest Absolute. All rights of the Trustee and security interests
hereunder, and all obligations of the Issuer hereunder, shall be absolute and unconditional
irrespective of, and the Issuer hereby irrevocably waives any defenses it may now have or may
hereafter acquire in any way relating to, any or all of the following:

          (a) any lack of validity or enforceability of any of the Deal Documents or any other
agreement or instrument relating thereto (other than against the Trustee);

          (b) any change in the time, manner or place of payment of, or in any other term of, all or
any of the Secured Obligations, or any other amendment or waiver of or any consent to any departure
from the Deal Documents or any other agreement or instrument relating thereto;

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          (c) any taking, exchange, surrender, release or non-perfection of any Collateral or any
other collateral, or any release or amendment or waiver of or consent to any departure from any
guaranty, for all or any of the Secured Obligations;

          (d) any manner of application of any Collateral or any other collateral, or proceeds
thereof, to all or any of the Secured Obligations, or any manner of sale or other disposition of
any Collateral or any other collateral for all or any of the Secured Obligations or any other
obligations of the Issuer under or in respect of the Deal Documents or any other assets of the
Issuer;

          (e) any change, restructuring or termination of the limited liability company structure or
existence of the Issuer;

          (f) the failure of any other Person to execute this Indenture or any other agreement or
the release or reduction of liability of the Issuer or other grantor or surety with respect to the
Secured Obligations; or

          (g) any other circumstance (including any statute of limitations) or any existence of or
reliance on any representation by the Trustee that might otherwise constitute a defense available
to, or a discharge of, the Issuer.

ARTICLE V

REPRESENTATIONS, WARRANTIES AND COVENANTS

     Section 5.1 Representations and Warranties. The Issuer represents and warrants, as of the date of
this Indenture, to the Trustee as follows:

          (a) The Issuer is a limited liability company duly formed, validly existing and in good
standing under the laws of the State of Delaware, is duly qualified to do business and in good
standing in the State of Delaware and has full limited liability company power and authority to
conduct its business and to execute, deliver and perform this Indenture, each other instrument to
be delivered by it pursuant to this Indenture and each other Deal Document to which it is a party,
and the Issuer is not in liquidation or bankruptcy and has not become subject to a Voluntary
Bankruptcy or an Involuntary Bankruptcy.

          (b) The Issuer has not engaged in any activities or become subject to any Losses or other
obligations since its organization (other than those incidental to its organization and permitted
by the Issuer Organizational Documents, the execution and performance of the Deal Documents to
which it is a party and the activities referred to in or contemplated by such agreements and, in
respect of Losses or other obligations since its organization, assuming the accuracy of the
representations and warranties of the Seller in the Purchase and Sale Agreement and the due and
timely performance by the Seller of its obligations under the Purchase and Sale Agreement), and the
Issuer has not paid any dividends or made any similar distributions since its organization.

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          (c) The creation of the Notes and the issuance, execution and delivery, and the compliance
by the Issuer with the terms, of the Notes and each of the other Deal Documents to which it is a
party:

          (i) do not at the Closing Date conflict with, result in a breach of any of the
terms or provisions of or constitute a default under (A) the Issuer Organizational Documents
or (B) assuming the accuracy of the representations and warranties of the Seller in the
Purchase and Sale Agreement and the due and timely performance by the Seller of its
obligations under the Purchase and Sale Agreement, any judgment, order or decree of any
Governmental Authority having jurisdiction over the Issuer, its assets or its properties or,
except where it would not be a Material Adverse Change, any Applicable Law; and

          (ii) assuming the accuracy of the representations and warranties of the Seller in
the Purchase and Sale Agreement and the due and timely performance by the Seller of its
obligations under the Purchase and Sale Agreement, do not at the Closing Date violate, or
constitute a default under, any deed, indenture, agreement or other instrument or obligation
to which the Issuer is a party or by which it or any part of its assets, property or
revenues are bound.

          (d) The creation, execution and issuance of the Notes, the execution and delivery by the
Issuer of the Deal Documents executed by it and the performance by the Issuer of its obligations
hereunder and thereunder and the arrangements contemplated hereby and thereby to be performed by it
have been duly authorized, executed and delivered by the Issuer.

          (e) This Indenture constitutes, and the other Deal Documents to which it is a party, when
duly authorized, executed and delivered by the other party or parties thereto, and, in the case of
the Notes, when issued and authenticated in accordance with the provisions of this Indenture, will
constitute, valid, legally binding and (subject to general equitable principles, and
laws relating to insolvency, liquidation, reorganization and other laws of general application
relating to creditors’ rights or claims or to laws of prescription or the concepts of materiality,
reasonableness, good faith and fair dealing) enforceable obligations of the Issuer.

          (f) Assuming the accuracy of the representations and warranties of the Seller in the
Purchase and Sale Agreement and the due and timely performance by the Seller of its obligations
under the Purchase and Sale Agreement, on the Closing Date, there exists no Event of Default nor
any event that, had the Notes already been issued, would constitute a Default or an Event of
Default.

          (g) On the Closing Date, subject to the Liens created in favor of the Trustee and except
for any other Permitted Liens, there exists no Lien over the assets of the Issuer.

          (h) Assuming the accuracy of the representations and warranties of the Seller in the
Purchase and Sale Agreement and the due and timely performance by the Seller of its obligations
under the Purchase and Sale Agreement, on the Closing Date, all consents, approvals, authorizations
or other orders of all Governmental Authorities required (excluding any required by the other
parties to the Deal Documents) for or in connection with the execution, delivery and

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performance of
the Deal Documents by the Issuer and the issuance and performance of the Notes and the offering of
the Notes by the Issuer have been obtained and are in full force and effect and are not contingent
upon fulfillment of any condition except for those required by the securities or blue sky laws of
various states. No consent of any Governmental Authority or any other party (including directors,
officers, partners, members, managers or creditors of the Issuer) is required that has not been
obtained for the pledge by the Issuer of the Collateral pursuant to this Indenture, except for such
consents as may have already been obtained.

          (i) Assuming compliance with Section 6.9 and after giving pro forma effect to the use of
proceeds as contemplated by the Memorandum, the Issuer would not be required to register as an
“investment company” within the meaning of the Investment Company Act of 1940, as amended.

          (j) Assuming the accuracy of the representations and warranties of the Seller in the
Purchase and Sale Agreement and the due and timely performance by the Seller of its obligations
under the Purchase and Sale Agreement, there is no action, suit, investigation or proceeding
pending or, to the knowledge of the Issuer, threatened against the Issuer before any Governmental
Authority that in any manner challenges or seeks to prevent, enjoin, alter or materially delay the
transactions contemplated by this Indenture and the other Deal Documents to which the Issuer is a
party.

          (k) The Issuer has no Subsidiaries.

          (l) Assuming the accuracy of the representations and warranties of the Seller in the
Purchase and Sale Agreement and the due and timely performance by the Seller of its obligations
under the Purchase and Sale Agreement, the Issuer is the sole legal and beneficial owner of the
Purchased Assets and the other assets and properties constituting the Collateral, free and clear of
any Liens other than Permitted Liens.

          (m) Under the laws of the State of Delaware, the laws of the State of New York and U.S.
federal law in force at the Closing Date, it is not necessary that this Indenture or any other Deal
Document (other than evidences and perfection of the Liens) be filed, recorded or enrolled by the
Issuer with any court or other Governmental Authority in any such jurisdictions or that any stamp,
registration or similar Tax be paid by the Issuer on or in relation to this Indenture or any of the
other Deal Documents (other than filings with the SEC, Uniform Commercial Code financing statements
set forth in Exhibit E, the notice to Counterparty contained in the Counterparty
Instruction and the various consents and agreements, if any, pursuant hereto).

          (n) The filings of financing statements under the UCC and other recordings, if any, in the
appropriate offices therefor and any other actions required to perfect a security interest in favor
of the Trustee in the Collateral, including the Purchased Assets sold, transferred, conveyed,
assigned, contributed and granted on the Closing Date pursuant to the Purchase and Sale Agreement,
have been or shall have been duly made by the Closing Date, and, subject to the terms and
provisions of this Indenture, the Issuer has or shall have the same rights as the Seller has or
would have with respect to the Purchased Assets (if the Seller were still the owner of such
Purchased Assets) against Counterparty. No other security agreement, financing statement or

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other
public notice with respect to all or any part of the Collateral (other than any of the foregoing
that is referenced in Exhibit E to this Indenture or otherwise names the Trustee as secured
party) is on file or of record in any public office that perfects a valid security interest
therein. This Indenture creates a valid security interest in the Collateral securing the payment
of the Secured Obligations.

          (o) Assuming the accuracy of the representations and warranties of the Seller in the
Purchase and Sale Agreement and the due and timely performance by the Seller of its obligations
under the Purchase and Sale Agreement, the Issuer has determined, and by virtue of its entering
into the transactions contemplated hereby and its authorization, execution and delivery of this
Indenture and the other Deal Documents to which it is party, that its incurrence of Indebtedness
and any other liability hereunder or thereunder or contemplated hereby or thereby, (i) does not
leave the fair saleable value of its assets less than the sum of its debts and other obligations,
including contingent liabilities, (ii) does not leave the present fair saleable value of its assets
less than the amount that would be required to pay its probable liabilities on its existing debts
and other obligations, including contingent liabilities, as they become absolute and matured, (iii)
does not leave it unable to realize upon its assets and pay its debts and other obligations,
including contingent obligations, as they mature, (iv) does not leave it with unreasonably small
capital with which to engage in its business or unable to pay its debts as they mature, (v) will
not cause it to become subject to any Voluntary Bankruptcy or Involuntary Bankruptcy and (vi) will
not render it insolvent within the meaning of Section 101(32) of the Bankruptcy Code. The Issuer
has not incurred and does not have present plans or intentions to incur debts or other obligations
or liabilities beyond its ability to pay such debts or other obligations or liabilities as they
become absolute and matured.

          (p) Assuming the accuracy of the representations and warranties of the Seller in the
Purchase and Sale Agreement and the due and timely performance by the Seller of its obligations
under the Purchase and Sale Agreement, no material adverse change in the business,
condition (financial or otherwise), operations, earnings, performance, properties or prospects
of the Issuer has occurred since its date of formation.

          (q) The Issuer is an entity that is disregarded as separate from the initial Equityholder
for U.S. federal income tax purposes. The Issuer has never filed any tax return or report under
any name other than its exact legal name. The Issuer has filed (or caused to be filed) all tax
returns and reports required by law to have been filed by it and has paid all Taxes required to be
paid by it. The Issuer does not have any express or implied obligation to indemnify any other
Person with respect to Taxes.

          (r) No step has been taken or is intended by the Issuer or, so far as it is aware, any
other Person for the winding-up, liquidation, dissolution, administration, merger or consolidation
or for the appointment of a receiver or administrator of the Issuer or all or any of its assets.

          (s) Subject to Permitted Liens, the Issuer has not assigned or pledged any of its right,
title or interest in the Collateral to anyone other than the Trustee.

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          (t) Assuming the accuracy of the representations and warranties of the Seller in the
Purchase and Sale Agreement and the due and timely performance by the Seller of its obligations
under the Purchase and Sale Agreement, the Issuer is in compliance with the requirements of all
Applicable Laws, a breach of any of which would be a Material Adverse Change.

          (u) The Issuer is not engaged in the business of extending credit for the purpose of
buying or carrying margin stock, and no portion of the Note Purchase Price shall be used by the
Issuer for a purpose that violates Regulation T, U or X promulgated by the Board of Governors of
the Federal Reserve System from time to time.

          (v) The representations and warranties made by the Issuer to the Noteholders in any of the
other Transaction Documents to which it is a party are true and accurate as of the date made.

     Section 5.2 Covenants. The Issuer covenants with the Trustee that, so long as any Notes are
Outstanding, it will perform and comply with each of the following covenants and not engage in any
activity prohibited by this Indenture without the prior written consent of the Trustee pursuant to
Section 9.1 or Section 9.2, as applicable, authorizing the Issuer not to perform any such covenants
or to engage in any such activity prohibited by this Indenture, in each case on such terms and
conditions, if any, as shall be specified in such prior written consent:

          (a) Except as described under Article IX, the Issuer shall not take any action, whether
orally or in writing, that would amend, waive, modify, supplement, restate, cancel or terminate, or
discharge or prejudice the validity or effectiveness of, this Indenture, the Notes, the Servicing
Agreement or the Pledge and Security Agreement, or permit any party to any such document to be
released from its obligations thereunder (unless, in each case, expressly permitted thereunder).

          (b) The Issuer shall not, directly or indirectly, (i) declare or pay any dividend or make
any distribution on its Capital Securities, whether in cash, property, securities or a combination
thereof, to the Equityholders or otherwise with respect to any ownership of the Issuer’s Capital
Securities, except that the Issuer may distribute to the Equityholders (x) any amounts pursuant to
Section 3.8, (y) pursuant to Section 3.7(b), all or any portion of any amounts transferred to the
Issuer pursuant to Section 3.7(a)(viii), or (z) any proceeds from an issuance of Notes or Capital
Securities in accordance with this Indenture, (ii) purchase, redeem, retire or otherwise acquire
for value any issued Capital Securities of the Issuer, (iii) make any payment of principal,
interest or Premium, if any, on the Notes or make any voluntary or optional redemption, repurchase,
defeasance or other acquisition or retirement for value of, or make any deposit (including the
payment of amounts into a sinking fund or other similar fund) with respect to, Indebtedness of the
Issuer other than as permitted by the Notes and this Indenture (including in connection with any
issuance or sale of any Subordinated Notes, Refinancing Notes or Capital Securities expressly
permitted by the Notes and this Indenture) or (iv) make any loan or advance to any Person, any
purchase or other acquisition of any beneficial interest, Capital Securities, warrants, rights,
options, obligations or other securities of such Person, any capital contribution to such Person or
any other investment in such Person (other than Eligible Investments and

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investments permitted
under Section 5.2(f)). The foregoing shall not restrict the Equityholder or its Affiliates (other
than the Issuer) from making open market purchases or otherwise acquiring or purchasing Notes.

          (c) The Issuer shall not (and shall not consent to the Equityholders taking any action
that would cause the Issuer to) incur or suffer to exist any Lien over or with respect to any of
the Issuer’s assets, including the Collateral, other than any Permitted Lien (including any
security interest created or required to be created hereunder, including in connection with the
issuance of any Subordinated Notes and any Refinancing Notes).

          (d) The Issuer shall not incur, create, issue, assume, Guarantee or otherwise become
liable for or with respect to, or become responsible for, the payment or performance of,
contingently or otherwise, whether present or future (in any such case, to “Incur”),
Indebtedness; provided, however, that the Issuer may Incur Indebtedness in respect
of the Original Class A Notes, any Subordinated Notes and any Refinancing Notes issued in
accordance with this Indenture.

          (e) Except as expressly permitted by the Deal Documents, the Issuer shall not liquidate or
dissolve and shall not consolidate with, merge with or into, sell, convey, transfer, lease or
otherwise dispose of the Purchased Assets or all or any portion of its other property and assets
to, or purchase or otherwise acquire all or substantially all of the assets of, any other Person,
or permit any other Person to merge with or into, or consolidate or otherwise combine with, the
Issuer.

          (f) The Issuer shall not, directly or indirectly, transfer, issue, deliver or sell, or
consent to transfer, issue, deliver or sell, any Capital Securities of the Issuer unless (i) such
Capital Securities are pledged to the Trustee pursuant to the Pledge and Security Agreement, (ii)
after giving effect to such issuance, delivery and sale, any such Equityholder is not subject to
Japanese withholding tax in respect of the Royalties and (iii) prior to such issuance, delivery or
sale, the Trustee shall have been provided with an Opinion of Counsel from a law firm with a
nationally recognized tax practice that such issuance, delivery or sale should not cause a
“significant modification” of the Notes for U.S. federal income tax purposes; provided,
however, that, notwithstanding anything in this Section 5.2(f)(iii), the Trustee shall not
be required to be provided with such an Opinion of Counsel if there has been a Change in Law and
counsel to such Equityholder determines in good faith that it is unable to render such an Opinion
of Counsel (whereas it would have been able to render such an Opinion of Counsel had the Change in
Law not occurred). Notwithstanding the foregoing, the Issuer is permitted to accept capital
contributions from the Equityholders after the Closing Date provided such amount is deposited into
the Capital Account and used only as permitted by Section 3.1(f).

          (g) The Issuer shall not engage in any business or activity other than entering into the
Purchase and Sale Agreement, the Servicing Agreement and this Indenture, purchasing, holding,
servicing and pledging the Purchased Assets, collecting the Royalties and any Currency Hedge
Payments, issuing Notes, issuing Capital Securities (subject to the provisions of Section 5.2(f)),
undertaking any action contemplated by the Purchase and Sale Agreement, the Servicing Agreement or
this Indenture or necessary or reasonably appropriate to maintain, enforce or enjoy the full
benefit of any current or residual rights granted by or arising out of the Purchase and Sale

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Agreement, the Servicing Agreement or this Indenture and entering into, remaining a party to, and
otherwise performing any of the obligations contemplated by, and exercising any right or remedy
granted to the Issuer pursuant to or arising out of, the Deal Documents and the Counterparty
License Agreement and other matters reasonably related thereto.

          (h) The Issuer shall not, directly or indirectly, enter into, renew or extend any
transaction (including the purchase, sale, lease or exchange of property or assets, or the
rendering of any service) with any Affiliate of the Issuer, except for (i) the Transaction
Documents and the Issuer Organizational Documents and (ii) engaging in transactions permitted by
the Transaction Documents and the Issuer Organizational Documents.

          (i) The Issuer shall not, without the written consent of the Independent Member, take any
action to become subject to a Voluntary Bankruptcy or an Involuntary Bankruptcy. The Issuer shall
promptly provide the Trustee with written notice of the institution of any proceeding by or against
the Issuer seeking to adjudicate it a bankrupt or insolvent, or seeking liquidation, winding-up,
reorganization, arrangement, adjustment, protection, relief or composition of its debts under any
law relating to bankruptcy, insolvency or reorganization or relief of debtors, or seeking the entry
of an order for relief or the appointment of a receiver, trustee or other similar official for it
or for any substantial part of its property. The Issuer shall not, without the written consent of
the Independent Member, take any action to waive, repeal, amend, vary, supplement or otherwise
modify any provisions of any of the Issuer Organizational Documents that require written consent of
the Independent Member. The Issuer shall comply with, and cause compliance with, the Issuer
Organizational Documents.

          (j) The Issuer shall not take any action to waive, repeal, amend, vary, supplement or
otherwise modify the Issuer Organizational Documents in a manner that would materially adversely
affect (x) the rights, remedies, privileges or preferences of the Noteholders or (y) the validity,
perfection or priority of the Lien on any Collateral (including the Purchased Assets) or any Issuer
Pledged Collateral.

          (k) The Issuer shall duly and punctually pay principal with respect to the Outstanding
Principal Balance, Premium, if any, and Interest Amount on the Notes in dollars in accordance with
the terms of this Indenture and such Notes; provided, that the Issuer shall be in
compliance with this covenant with respect to any Payment Date (other than the Final Legal Maturity
Date or any Redemption Date subject to Section 3.10(b)) if any such interest in excess of the
portion of the Available Collections Amount available to pay such interest on the relevant Payment
Date and funds in the Interest Reserve Account and the Capital Account (subject to Section 3.8) are
paid in full not later than the next succeeding Payment Date (together with Additional Interest
thereon).

          (l) The Issuer shall not employ any employees other than as required by any provisions of
local law; provided, that the Members, the Manager and the Service Providers shall not be
deemed to be employees for purposes of this Section 5.2(l).

          (m) The Issuer shall not (v) assign, amend, waive, modify, supplement, restate, cancel or
terminate (or consent to any cancellation or termination of) the Purchase and Sale Agreement or the
Currency Hedge Agreement, (w) breach any of the provisions of the Purchase

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and Sale Agreement, (x)
enter into any new agreement in respect of the Purchased Assets or RAPIACTA in respect of the
Territory, (y) waive any obligation of, or grant any consent to, the Seller under or in respect of
the Purchased Assets, the Purchase and Sale Agreement, the Currency Hedge Agreement or RAPIACTA in
respect of the Territory or the Counterparty License Agreement or (z) consent to an assignment of
the Purchase and Sale Agreement by the Seller, the Counterparty License Agreement by Counterparty
or the Currency Hedge Agreement by the Currency Hedge Provider. Nothing in this Section 5.2(m)
shall prohibit the Issuer from taking any action reasonably requested by the Seller to facilitate
any cancellation, unwind, termination, disposition, amendment or modification of an Option or the
Currency Hedge Agreement permitted by Section 4.11 of the Purchase and Sale Agreement.

          (n) The Issuer shall at all times use its commercially reasonable efforts to exercise and
enforce its rights and remedies under the Purchase and Sale Agreement, the Servicing Agreement, the
Currency Hedge Agreement, the Counterparty License Agreement and any agreement entered into in
connection with the execution of foreign currency exchange transactions permitted or required by
this Indenture, in each case, in a timely and commercially reasonable manner; provided,
that, following the occurrence and continuation of an Event of Default, the Issuer shall give
notice to the Trustee on behalf of the Noteholders of any contemplated enforcement of such rights
and remedies and will follow any Direction regarding enforcement of such rights and remedies
provided by Noteholders of a majority of the Outstanding Principal Balance of the Senior Class of
Notes (or the Senior Trustee on their behalf) that it has received.

          (o) The Issuer shall maintain its existence separate and distinct from any other Person in
all material respects, including using its commercially reasonable efforts in taking the following
actions, as appropriate:

          (i) maintaining in full effect its existence, properties, rights and franchises as
a Delaware limited liability company and obtaining and preserving its qualification to do
business in each jurisdiction in which such qualification is necessary
to protect the validity and enforceability of this Indenture and each other instrument
or agreement necessary to properly administer this Indenture and permit and effectuate the
transactions contemplated hereby and thereby;

          (ii) maintaining its own deposit accounts, separate from those of the
Equityholders, the Manager, any of the Members (including the Independent Member) and their
respective Affiliates;

          (iii) conducting its affairs separately from those of the Equityholders, the
Manager, any of the Members (including the Independent Member) or any of their respective
Affiliates and maintaining separate books, records and accounts and financial statements in
accordance with GAAP, including in connection with the purchase of the Purchased Assets from
the Seller; provided, however, that activities conducted by the Servicer in
its capacity as such will not be deemed to violate this Section 5.2(o)(iii);

          (iv) acting solely in its own name and not that of any other Person, including the
Equityholders, the Manager, any of the Members (including the

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Independent Member) or any of
their respective Affiliates, and at all times using its own stationery, invoices and checks
separate from those of the Equityholders, the Manager, any of the Members (including the
Independent Member) or any of their respective Affiliates;

          (v) not holding itself out as having agreed to pay or guarantee, or as otherwise
being liable for, the obligations of the Equityholders, the Manager, any of the Members
(including the Independent Member) or any of their respective Affiliates;

          (vi) causing any financial reports prepared by the Issuer and disclosing the
accounting effects of the purchase of the Purchased Assets from the Seller to be in
compliance with GAAP;

          (vii) maintaining all of its assets in its own name and not commingling its assets
with those of any other Person except as permitted or required under the Transaction
Documents;

          (viii) paying its own operating expenses and other liabilities out of its own
funds;

          (ix) observing all formalities required by the Issuer Organizational Documents;

          (x) not acquiring obligations of the Equityholders, the Manager, any of the Members
(including the Independent Member) or any of their respective Affiliates except as permitted
or required under the Transaction Documents;

          (xi) holding itself out to the public as a legal entity separate and distinct from
any other Person, including the Equityholders or any Affiliate of any Equityholder;

          (xii) correcting any known misunderstanding regarding its separate identity;

          (xiii) not forming, acquiring or holding any Subsidiary;

          (xiv) not sharing any common logo with or identifying itself as a department or
division of the Equityholders, the Manager, any of the Members (including the Independent
Member) or any of their respective Affiliates; provided, however, that the
Issuer may identify itself as an investment of and as owned and/or managed by any such
Equityholders or any of their respective Affiliates, as a Subsidiary of the Seller and as
employing the Servicer to act on its behalf pursuant to the Servicing Agreement;

          (xv) except as permitted by Section 5.2(g), conducting no material transactions
between the Issuer and the Equityholders, other than entering into and performing its
obligations under the Transaction Documents to which it is party, receiving any capital
contributions from the Equityholders, entering into and performing its obligations under the
Servicing Agreement, or as otherwise permitted by the Transaction Documents; and

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          (xvi) allocating fairly and reasonably the cost of any shared overhead expenses,
including office space, if applicable, with the Equityholders, the Manager, any of the
Members (including the Independent Member) or any of their respective Affiliates.

          (p) The Issuer shall provide written notice to the Trustee of any capital contributions
received by the Issuer from any Equityholder and will immediately forward any such amounts to the
Trustee for deposit in the Capital Account.

          (q) The Issuer will not change, amend or alter its exact legal name at any time except
following 30 days’ notice given by the Issuer to the Trustee.

          (r) The Issuer will not assign or pledge, so long as the assignment hereunder shall remain
in effect and has not been terminated pursuant to Section 11.1, any of its right, title or interest
in the Collateral hereby assigned to anyone other than the Trustee; provided, that the sale
or other disposition of the Capital Securities of the Issuer by any Equityholder (or any interest
therein) in compliance with the Pledge and Security Agreement or any issuance of Capital Securities
by the Issuer (subject to the provisions of Section 5.2(f)) shall not be considered a violation of
this Section 5.2(r).

          (s) The Issuer agrees that, at any time and from time to time, at the Issuer’s expense and
upon the Trustee’s written request, the Issuer will promptly and duly execute and deliver or cause
to be duly executed and delivered any and all such further instruments and documents, and take all
further action, that may be necessary in the reasonable discretion of the Trustee, in order to
perfect the security interest in the Collateral and to carry out the provisions of this Indenture
or to enable the Trustee to exercise and enforce its rights and remedies hereunder with respect to
any Collateral. The Issuer also agrees that, at any time and from time to time, at the Issuer’s
expense, the Issuer will file (or cause to be filed) such UCC continuation statements and such
other instruments or notices as may be necessary, including UCC financing statements or amendments
thereto, that the Trustee may reasonably request in order to perfect and preserve
the security interests and other rights granted or purported to be granted to the Trustee
hereby. With respect to the foregoing and the grant of the security interest hereunder, the Issuer
hereby authorizes the Trustee to file one or more financing or continuation statements, and
amendments thereto, relative to all or any part of the Collateral. The Issuer hereby authorizes
the Trustee to file financing statements describing as the collateral covered thereby “all of the
debtor’s personal property or assets” or words to that effect, notwithstanding that such wording
may be broader in scope than the Collateral described in this Indenture.

          (t) The Issuer will maintain in the Borough of Manhattan, The City of New York, an office
or agency of the Trustee, Registrar and Paying Agent where Notes may be presented or surrendered
for payment, where Notes may be surrendered for registration of transfer, exchange or purchase and
where notices and demands to or upon the Issuer in respect of the Notes and this Indenture may be
served. Each of the Corporate Trust Office and each office or agency of the Trustee in the Borough
of Manhattan, The City of New York shall initially be one such office or agency for all of the
aforesaid purposes. The Issuer shall give prompt written notice to the Trustee of the location,
and of any change in the location, of any such office or agency (other than a change in the
location of the office of the Trustee). If at any time the Issuer shall fail to maintain any such
required office or agency or shall fail to furnish the Trustee with

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the address thereof, such
presentations, surrenders, notices and demands may be made or served at the address of the Trustee
set forth in Section 12.5. The Issuer may also from time to time designate one or more other
offices or agencies where the Notes may be presented or surrendered for any or all such purposes
and may from time to time rescind such designations; provided, however, that no
such designation or rescission shall in any manner relieve the Issuer of its obligation to maintain
an office or agency in the Borough of Manhattan, The City of New York, for such purposes.

          (u) The Issuer shall use commercially reasonable efforts to file any form (or comply with
any other administrative formalities) required for an exemption from or a reduction of any
withholding tax for which it is eligible. The Issuer shall maintain its status as an entity that
is not classified as a corporation or publicly traded partnership taxable as a corporation for U.S.
federal income tax purposes. The Issuer shall use commercially reasonable efforts to maintain its
status as either (i) an entity that is disregarded as separate from the Equityholder if there is
one Equityholder for U.S. federal income tax purposes or (ii) a partnership if there is more than
one Equityholder for U.S. federal income tax purposes, in each case for U.S. federal income tax
purposes and, to the extent permitted by Applicable Law, state and local tax purposes. The Issuer
shall not file any tax return or report under any name other than its exact legal name. The Issuer
shall treat the Notes as debt for U.S. federal income tax purposes. Neither the Issuer nor the
Trustee shall treat any Noteholder or Beneficial Holder as a “partner” of the Issuer for U.S.
federal income tax purposes with respect to the ownership of the Notes. The Issuer and the Trustee
will treat all interest paid or otherwise accruing on the Notes as interest for U.S. federal income
tax purposes. The Issuer will prepare and file all tax returns of the Issuer consistent with the
covenants set forth in this Section 5.2(u) and will not take any inconsistent position in any
communication or agreement with any taxing authority unless required by a final “determination” of
a court of law within the meaning of Section 1313(a)(1) of the Code. The Issuer shall not enter
into or incur any express or implied obligation to indemnify any other Person with respect to
Taxes. The Issuer shall file (or cause to be filed) all tax returns and reports required by law to
be filed by it and pay all Taxes required to be paid by it.

          (v) The Issuer shall timely and fully perform and comply with each of its duties and
obligations to the Noteholders under the Transaction Documents to which it is a party, including
all covenants, conditions and other provisions with respect to the Purchased Assets;
provided, that the Issuer shall be in compliance with this Section 5.2(v) with respect to
any Payment Date (other than the Final Legal Maturity Date or any Redemption Date) if any such
interest in excess of the portion of the Available Collections Amount available to pay such
interest on the relevant Payment Date and funds in the Interest Reserve Account and the Capital
Account (subject to Section 3.8) are paid in full not later than the next succeeding Payment Date
(together with Additional Interest thereon).

          (w) During any period in which the Issuer is not subject to Section 13 or 15(d) of the
Exchange Act, the Issuer shall make available to any Noteholder or Beneficial Holder in connection
with any sale of any or all of its Notes and any prospective purchaser of such Notes from such
Noteholder or Beneficial Holder the information required by Rule 144A(d)(4) under the Securities
Act.

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          (x) The Issuer shall not, and shall not permit any of its Affiliates to, directly or
indirectly, pay or cause to be paid any consideration of any type or form (whether in cash,
property, by way of interest or fee or otherwise) to or for the benefit of any Noteholder or
Beneficial Holder for or as an inducement to any forbearance, consent, waiver or amendment of any
of the terms or provisions hereof or of the Notes, or any agreement in respect thereof, unless such
consideration is, on the same terms and conditions, offered to all Noteholders and Beneficial
Holders and paid to all Noteholders and Beneficial Holders that agree to such forbearance, consent,
waiver or amendment, or agreement in respect thereof.

     Section 5.3 Reports and Other Deliverables by the Issuer.

          (a) The Issuer shall furnish to the Trustee, within 120 days after the end of each fiscal
year commencing with the fiscal year ending December 31, 2011, a certificate from a Responsible
Officer of the Issuer as to his or her knowledge of the Issuer’s compliance with all of its
obligations under this Indenture (it being understood that, for purposes of this Section 5.3, such
compliance shall be determined without regard to any period of grace or requirement of notice
provided under this Indenture but shall reflect any Interest Amount paid on the Original Class A
Notes (other than on the Final Legal Maturity Date) by the Payment Date immediately following the
Payment Date on which such Interest Amount was first payable as contemplated by the proviso to
Section 5.2(k) as have been timely paid).

          (b) The Issuer shall deliver written notice to the Trustee of the occurrence of any
Default or Event of Default under this Indenture promptly and in any event within five Business
Days of a Responsible Officer of the Issuer (including the Manager) becoming aware of such Default
or Event of Default.

          (c) The Issuer shall promptly (and in any event within five Business Days of receipt
thereof) provide to the Trustee and the Servicer copies of written materials that the Issuer
receives from the Seller pursuant to Sections 4.1, 4.5, 4.7, 4.11 and 4.12 of the Purchase and Sale
Agreement or otherwise in respect of the Counterparty License Agreement; provided,
however, that the Issuer shall not be required to provide any written materials received by
it from the
Seller to the extent such materials are not, in the reasonable judgment of the Issuer,
material in the context of the Royalties or the transactions contemplated by the Deal Documents.

          (d) Within 120 days after the beginning of each fiscal year commencing with the fiscal
year beginning January 1, 2012, the Issuer shall furnish to the Trustee an opinion of its legal
counsel, which opinion shall state either that (i) in the opinion of such counsel, all action has
been taken with respect to any filing, re-filing, recording or re-recording with respect to the
Collateral as is necessary to maintain the security interest on the Collateral in favor of the
Trustee and the Noteholders, or (ii) in the opinion of such counsel, no such action is necessary to
maintain such security interest.

ARTICLE VI

THE TRUSTEE

     Section 6.1 Acceptance of Trusts and Duties. Except during the continuance of an Event of
Default, the Trustee undertakes to perform such duties and only such duties as are

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specifically set
forth in this Indenture, and no implied covenants or obligations shall be read into this Indenture
against the Trustee; provided, that, to the extent those duties are qualified, limited or
otherwise affected by the provisions of any other Deal Document, the Trustee shall be required to
perform those duties only as so qualified, limited or otherwise affected. The duties and
responsibilities of the Trustee shall be as provided by the Trust Indenture Act (as if the Trust
Indenture Act applied to this Indenture) and as set forth herein. The Trustee accepts the trusts
hereby created and applicable to it and agrees to perform the same but only upon the terms of this
Indenture and the Trust Indenture Act (as if the Trust Indenture Act applied to this Indenture) and
agrees to receive and disburse all moneys received by it in accordance with the terms hereof. The
Trustee in its individual capacity shall not be answerable or accountable under any circumstances
except for its own willful misconduct or negligence or breach of any of its representations or
warranties set forth herein, and the Trustee shall not be liable for any action or inaction of the
Issuer or any other parties to any of the Deal Documents. Any amounts received by or due to the
Trustee under this Indenture, including the fees, out-of-pocket expenses and indemnities of the
Trustee, shall be Expenses of the Issuer.

     The Issuer does hereby constitute and appoint the Trustee the true and lawful attorney of the
Issuer, irrevocably, granted for good and valuable consideration and coupled with an interest and
with full power of substitution, and with full power (in the name of the Issuer or otherwise), to
ask, require, demand, receive, compound and give acquittance for any and all monies and claims for
monies (in each case including insurance and requisition proceeds) due and to become due under or
arising out of any Deal Document and all other property that now or hereafter constitutes part of
the Indenture Estate, to endorse any checks or other instruments or orders in connection therewith
and to file any claims or take any action or institute any proceedings that the Trustee may deem to
be necessary or advisable in the premises; provided, that the Trustee shall not exercise
any such rights except upon the occurrence and during the continuance of an Event of Default
hereunder in accordance with Section 4.3.

     Section 6.2 Copies of Documents and Other Notices.

          (a) The Trustee, upon written request, shall furnish to each requesting Noteholder or
Beneficial Holder included on the Approved Holder List and the Servicer, promptly upon receipt
thereof, duplicates or copies of all reports, Notices, requests, demands, certificates, financial
statements and other instruments furnished to the Trustee under or in connection with this
Indenture.

          (b) The Trustee shall furnish to Noteholders and Beneficial Holders included on the
Approved Holder List and the Servicer promptly after receipt thereof any reports or notices
received from any of the Issuer, the Equityholders, the Seller, the Currency Hedge Provider or
Counterparty.

     Section 6.3 Representations and Warranties. The Trustee does not make and shall not be deemed to
have made any representation or warranty as to the validity, legality or enforceability of this
Indenture, the Notes or any other document or instrument or as to the correctness of any statement
contained in any thereof, except that the Trustee in its individual capacity hereby represents and
warrants as follows:

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          (a) The Trustee is a national banking association and is validly existing and in good
standing under the laws of the United States, and is duly authorized and licensed under applicable
law to conduct its business as presently conducted.

          (b) The Trustee has all requisite right, power and authority to execute and deliver this
Indenture and its related documents and to perform all of its duties as Trustee hereunder and
thereunder.

          (c) The execution and delivery by the Trustee of this Indenture and the other Deal
Documents to which it is a party, and the performance by the Trustee of its duties hereunder and
thereunder, have been duly authorized by all necessary corporate proceedings, and no further
approvals or filings, including any governmental approvals, are required for the valid execution
and delivery by the Trustee, or the performance by the Trustee, of this Indenture and such other
Deal Documents to which it is a party.

          (d) The execution, delivery and performance by the Trustee of this Indenture and the other
Deal Documents to which it is a party (i) to the best of the Trustee’s knowledge and without
independent inquiry or investigation into the facts thereto, do not violate any provision of any
Applicable Law and (ii) do not violate any provision of its corporate charter or by-laws.

          (e) The execution, delivery and performance by the Trustee of this Indenture and the other
Deal Documents to which it is a party, to the best of the Trustee’s knowledge and without
independent inquiry or investigation into the facts thereto, do not require the authorization,
consent or approval of, the giving of notice to, the filing or registration with, or the taking of
any action in respect of, any Governmental Authority.

          (f) The Trustee has duly executed and delivered this Indenture and each other Deal
Document to which it is a party, and each of this Indenture and each such other Deal
Document constitutes the legal, valid and binding obligation of the Trustee in accordance with
its terms, except as (i) such enforceability may be limited by bankruptcy, insolvency,
reorganization, moratorium and similar laws relating to or affecting the enforcement of creditors’
rights generally and (ii) the availability of equitable remedies may be limited by equitable
principles of general applicability.

          (g) The Trustee meets the requirements of Section 6.9.

     Section 6.4 Reliance; Agents; Advice of Counsel. The Trustee shall incur no liability to anyone
acting upon any signature, instrument, notice, resolution, request, consent, order, certificate,
report, opinion, bond or other document or paper believed by it to be genuine and believed by it to
be signed by the proper party or parties. The Trustee may accept a copy of a resolution of the
governing body of any party to any Deal Document (including the Issuer), certified in an
accompanying Officer’s Certificate as duly adopted and in full force and effect, as conclusive
evidence that such resolution has been duly adopted and that the same is in full force and effect.
As to any fact or matter the manner of ascertainment of which is not specifically described herein,
the Trustee shall be entitled to receive and may for all purposes hereof conclusively rely on a
certificate, signed by an officer of any duly authorized Person, as to such fact or matter, and
such certificate shall constitute full protection to the Trustee for any action

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taken or omitted to
be taken by it in good faith in reliance thereon. To the extent not otherwise specifically
provided herein, the Trustee shall assume, and shall be fully protected in assuming, that the
Issuer is authorized by its constitutional documents to enter into this Indenture and to take all
action permitted to be taken by it pursuant to the provisions hereof and shall not be required to
inquire into the authorization of the Issuer with respect thereto. To the extent not otherwise
specifically provided herein, the Trustee shall furnish to the Issuer or the Servicer upon written
request such information and copies of such documents as the Trustee may have and as are necessary
for the Issuer or any such Servicer to perform its duties under Article II and Article III or
otherwise.

     The Trustee shall not be liable for any action it takes or omits to take in good faith that it
believes to be authorized or within its rights or powers or for any action it takes or omits to
take in accordance with the Direction of the Noteholders in accordance with Section 4.12 relating
to the time, method and place of conducting any proceeding for any remedy available to the Trustee,
or exercising any trust, right or power conferred upon the Trustee, under any Transaction Document.

     The Trustee may execute any of the trusts or powers hereunder or perform any duties hereunder
or under any other Transaction Document either directly or by or through agents or attorneys or a
custodian or nominee, and the Trustee shall not be responsible for any misconduct or negligence on
the part of, or for the supervision of, any such agent, attorney, custodian or nominee appointed
with due care by it hereunder.

     The Trustee may consult with counsel as to any matter relating to this Indenture or any other
Transaction Document and any Opinion of Counsel or any advice of such counsel shall be full and
complete authorization and protection in respect of any action taken or suffered or omitted by it
hereunder in good faith and in accordance with such advice or Opinion of Counsel.

     The Trustee shall be under no obligation to exercise any of the rights or powers vested in it
by this Indenture or any other Transaction Document, or to institute, conduct or defend any
litigation hereunder or in relation hereto, at the request, order or Direction of any of the
Noteholders, pursuant to the provisions of this Indenture or any other Transaction Document, unless
such Noteholders shall have offered to the Trustee security or indemnity reasonably satisfactory to
it against the costs, expenses and liabilities that may be incurred therein or thereby.

     The Trustee shall not be required to expend or risk its own funds or otherwise incur any
financial liability in the performance of any of its duties hereunder or under any other
Transaction Document, or in the exercise of any of its rights or powers, if there is reasonable
ground for believing that the repayment of such funds or indemnity satisfactory to it against such
risk or liability is not reasonably assured to it, and none of the provisions contained in this
Indenture or any other Transaction Document shall in any event require the Trustee to perform, or
be responsible or liable for the manner of performance of, any obligations of the Issuer or the
Servicer under this Indenture or any of the other Transaction Documents.

     The Trustee shall not be liable for any Losses or Taxes (except for Taxes relating to any
compensation, fees or commissions of any entity acting in its capacity as Trustee hereunder) or

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in
connection with the selection of Eligible Investments or for any investment losses resulting from
Eligible Investments.

     When the Trustee incurs expenses or renders services in connection with an Acceleration
Default, such expenses (including the fees and expenses of its counsel) and the compensation for
such services are intended to constitute expenses of administration under any bankruptcy law or law
relating to creditors’ rights generally.

     The Trustee shall not be charged with knowledge of an Event of Default unless a Responsible
Officer of the Trustee obtains actual knowledge of such event or has received written notice of
such event at its Corporate Trust Office from the Issuer, the Servicer or Noteholders of not less
than 10% of the Outstanding Principal Balance of the Notes.

     The Trustee shall have no duty to monitor the performance of the Issuer, the Servicer or any
other party to the Deal Documents, nor shall it have any liability in connection with the
malfeasance or nonfeasance by such parties.

     Whenever in the administration of the provisions of this Indenture the Trustee shall deem it
necessary or desirable that a matter be proved or established prior to taking or suffering any
action to be taken hereunder or under any other Transaction Document, such matter (unless other
evidence in respect thereof be herein specifically prescribed) may, in the absence of gross
negligence or bad faith on the part of the Trustee, be deemed to be conclusively proved and
established by a certificate signed by a Responsible Officer of the Issuer and delivered to the
Trustee, and such certificate, in the absence of gross negligence or bad faith on the part of the
Trustee, shall be full warrant to the Trustee for any action taken, suffered or omitted by it under
the provisions of this Indenture or any other Transaction Document upon the faith thereof.

     Except as provided expressly hereunder, the Trustee shall have no obligation to invest and
reinvest any cash held in the Accounts in the absence of timely and specific written investment
direction by or on behalf of the Issuer. In no event shall the Trustee be liable for the selection
of investments or for investment losses incurred thereon. The Trustee shall have no liability in
respect of losses incurred as a result of the liquidation of any investment prior to its stated
maturity or the failure of the Issuer to provide timely written investment direction.

     When the Trustee incurs expenses after the occurrence of a Default specified in Section 4.1
with respect to the Issuer, if the surviving entity has failed to honor such obligation, the
expenses are intended to constitute expenses of administration under any insolvency law or under
the Bankruptcy Code.

     Section 6.5 Not Acting in Individual Capacity. The Trustee acts hereunder solely as trustee
unless otherwise expressly provided, and all Persons, other than the Noteholders to the extent
expressly provided in this Indenture, having any claim against the Trustee by reason of the
transactions contemplated hereby shall look, subject to the lien and priorities of payment as
provided herein or in any other Transaction Document, only to the property of the Issuer for
payment or satisfaction thereof.

     Section 6.6 Compensation of Trustee. The Trustee agrees that it shall have no right against the
Noteholders or, except as provided in Section 3.7(a), the property of the Issuer, for

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any fee as
compensation for its services hereunder. The Issuer shall pay to the Trustee from time to time
such compensation as is agreed between the two parties. The priority of such compensation shall be
subject to Section 3.7(a).

     Section 6.7 Notice of Defaults. As promptly as practicable after, and in any event within 30 days
after, the occurrence of any Default hereunder, the Trustee shall transmit by mail to the Issuer,
the Servicer and the Noteholders of the related class, in accordance with Section 313(c) of the
Trust Indenture Act (as if the Trust Indenture Act applied to this Indenture), notice of such
Default hereunder actually known to a Responsible Officer of the Trustee, unless such Default shall
have been cured or waived; provided, however, that, except in the case of a Default
on the payment of the interest, principal or Premium, if any, on any Note, the Trustee shall be
fully protected in withholding such notice if and so long as a trust committee of Responsible
Officers of the Trustee in good faith determines that the withholding of such notice is in the
interests of the Noteholders of the related class.

     Section 6.8 May Hold Notes. The Trustee, any Paying Agent, the Registrar or any of their
Affiliates or any other agent in their respective individual or any other capacity may become the
owner or pledgee of the Notes and, subject to Sections 310(b) and 311 of the Trust Indenture Act
(as if the Trust Indenture Act applied to this Indenture), may otherwise deal with the Issuer with
the same rights it would have if it were not the Trustee, Paying Agent, Registrar or such other
agent.

     Section 6.9 Corporate Trustee Required; Eligibility. There shall at all times be a Trustee that
shall (a) be eligible to act as a trustee under Section 310(a) of the Trust Indenture Act (as if
the Trust Indenture Act applied to this Indenture), (b) meet the requirements of Rule 3a-7(a)(4)(i)
under the Investment Company Act of 1940, as amended, and (c) meet the Eligibility Requirements.
If such corporation publishes reports of conditions at least annually, pursuant to law or to the
requirements of any federal, state, foreign, territorial or District of Columbia supervising or
examining authority, then, for the purposes of this Section 6.9, the combined capital and surplus
of such corporation shall be deemed to be its combined capital and surplus as set forth in its most
recent report of conditions so published.

     In case at any time the Trustee shall cease to be eligible in accordance with the provisions
of this Section 6.9 to act as Trustee, the Trustee shall resign immediately as Trustee in the
manner and with the effect specified in Section 7.1.

     Section 6.10 Reports by the Trustee. Within 60 days after May 15 of each year commencing with the
first full calendar year following the issuance of any class of Notes, the Trustee shall, if
required by Section 313(a) of the Trust Indenture Act (as if the Trust Indenture Act applied to
this Indenture), transmit to the Noteholders of each class, as provided in Section 313(c) of the
Trust Indenture Act (as if the Trust Indenture Act applied to this Indenture), a brief report
describing, among other things, any changes in eligibility and qualifications of the Trustee and
any Subordinated Note Issuance.

     Section 6.11 Pledge and Security Agreement and Other Deal Documents. The Trustee shall enter into
the Pledge and Security Agreement with the Equityholders on the Closing Date and shall hold the
collateral pledged thereunder as part of the Collateral and the Indenture Estate

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for purposes of
this Indenture. The provisions of this Article VI shall apply to the Trustee’s exercise of rights
and remedies under the Pledge and Security Agreement, mutatis mutandis. In addition, the Trustee
shall enter into such other Deal Documents on the Closing Date to which it is party.

     Section 6.12 Custody of the Collateral. The Trustee shall hold such of the Indenture Estate as
consists of instruments, deposit accounts, negotiable documents, money, goods, letters of credit
and advices of credit in the State of New York. The Trustee shall hold such of the Indenture
Estate as constitutes investment property through a securities intermediary, which securities
intermediary shall agree with the Trustee that (a) such investment property shall at all times be
credited to a securities account of the Trustee, (b) such securities intermediary shall treat the
Trustee as entitled to exercise the rights that comprise each financial asset credited to such
securities account, (c) all property credited to such securities account shall be treated as a
financial asset, (d) such securities intermediary shall comply with entitlement orders originated
by the Trustee without the further consent of any other Person, (e) such securities intermediary
will not agree with any Person other than the Trustee to comply with entitlement orders originated
by such other Person, (f) such securities account and the property credited thereto shall not be
subject to any lien, security
interest or right of set-off in favor of such securities intermediary or anyone claiming
through it (other than the Trustee) and (g) such agreement shall be governed by the laws of the
State of New York. Except as permitted by this Section 6.12 or as otherwise permitted by any
Transaction Document, the Trustee shall not hold any part of the Indenture Estate through an agent
or a nominee.

     Section 6.13 Preservation and Disclosure of Noteholder Lists. The Registrar shall preserve, in as
current a form as is reasonably practicable, all information as to the names and addresses of the
Noteholders received by it, including the Approved Holder List. At any time when a default or an
Event of Default has occurred and is continuing, in case either (a) three or more Noteholders that
have executed and delivered to the Registrar a Confidentiality Agreement or (b) one or more
Noteholders of at least 25% of the Outstanding Principal Balance of the Senior Class of Notes that
have executed and delivered to the Registrar a Confidentiality Agreement (in each case,
“Applicants”) apply in writing to the Registrar and furnish to the Registrar reasonable
proof that each such Applicant has owned a Note for a period of at least three months preceding the
date of such application, and such application states that the Applicants desire to communicate
with other Noteholders with respect to their rights under this Indenture or under the Notes and
such application is accompanied by a copy of the form of proxy or other communication that such
Applicants propose to transmit, then the Registrar shall, within five Business Days after the
receipt of such application, inform such Applicants as to the approximate number of Noteholders
whose names and addresses appear in such information and as to the approximate cost of mailing to
such Noteholders the form of proxy or other communication, if any, specified in such application.
The Registrar shall, upon the written request of such Applicants, mail to each Noteholder whose
name and address appears in such information a copy of the form of proxy or other communication
that is specified in such request, with reasonable promptness after a tender to the Registrar of
the material to be mailed and of payment, or provision for the payment, of the reasonable expenses
of mailing. Each and every Noteholder, by receiving and holding the same, agrees with the Issuer
and the Registrar that neither the Registrar nor any agent of the Issuer or the Registrar shall be
held accountable by reason of mailing any material pursuant to a request made under this Section
6.13.

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     Section 6.14 Audit Rights.

          (a) At the Direction of Noteholders of at least 35% of the Outstanding Principal Balance
of the Senior Class of Notes, the Senior Trustee shall instruct the Servicer on behalf of the
Issuer to exercise the Issuer’s rights pursuant to Section 9.8 of the Counterparty License
Agreement to have the financial books and records of Counterparty audited by an independent
certified public accountant permitted by the Counterparty License Agreement (which audit may only
be made at the times and in the manner provided by and otherwise in conformity with the
requirements of the audit rights of the Seller provided for by Section 9.8 of the Counterparty
License Agreement), and the Issuer shall promptly provide to the Trustee for distribution to
Noteholders and Beneficial Holders on the Approved Holder List within five Business Days after
receipt thereof any written report that the Issuer receives with respect to such inspection or
audit, which written report shall be treated confidentially pursuant to the terms of the
Confidentiality Agreement; provided, however, that nothing in this Section 6.14(a)
shall prohibit or restrict the
Issuer’s ability to unilaterally exercise its rights pursuant to Section 4.7 of the Purchase
and Sale Agreement in the absence of any such Direction of the Noteholders.

          (b) At the Direction of Noteholders of at least 35% of the Outstanding Principal Balance
of the Senior Class of Notes, the Issuer shall, upon not less than ten Business Days’ prior written
notice to the Issuer, permit an independent public accounting firm of nationally recognized
standing selected by such Noteholders to make such inspection and audit of the books and records of
the Issuer as may reasonably be necessary to determine the correctness of any Distribution Report,
including the calculations made by the Calculation Agent in respect of any Calculation Date, as set
forth in Section 3.5, and the payments made pursuant to Section 3.7 with respect thereto. Such
inspection and audit (x) may not be conducted more than once during any calendar year, (y) shall be
conducted by such accounting firm during normal business hours at such place or places where such
books and records are held and (z) may not be conducted more than once in respect of any given
Calculation Date. Subject to this Section 6.14(b), the Issuer shall make available to such
accounting firm such books and records of the Issuer reasonably pertinent to such inspection and
audit and shall reasonably cooperate with such accounting firm in connection therewith. Any and
all fees and expenses of such accounting firm incurred in connection with any such inspection and
audit (the “Audit Expenses”) shall constitute Expenses; provided, that any and all
such Audit Expenses exceeding $20,000 per annum shall be borne solely by the Noteholders in
accordance with Section 3.7(d) if the report prepared by such accounting firm does not disclose
that there was a shortfall of 5% or more in the amounts paid during such period(s) when compared to
the amounts that should have been paid during such period(s) in accordance with this Indenture.
Such accounting firm shall prepare a report disclosing its conclusions with respect to the accuracy
or inaccuracy of the amounts inspected and audited and shall furnish such report to the Trustee for
distribution to Noteholders and Beneficial Holders on the Approved Holder List. In the event of
any inaccuracy reported by such accounting firm, the Issuer shall cause the amounts to be paid to
the Collection Account for distribution on the immediately succeeding Payment Date pursuant to
Section 3.7(a) to be adjusted in accordance with Section 3.7(d).

     Section 6.15 Compliance with Applicable Anti-Terrorism and Anti-Money Laundering Regulations. In
order to comply with Applicable Laws in effect from time to time applicable to banking
institutions, including those relating to the funding of terrorist activities and money

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laundering,
the Trustee is required to obtain, verify and record certain information relating to Persons that
maintain a business relationship with the Trustee. Accordingly, the Issuer agrees to provide to
the Trustee upon its request from time to time such identifying information and documentation as
may be available for the Issuer in order to enable the Trustee to comply with such Applicable Laws.

     Section 6.16 Jurisdiction of Trustee. Each of the Issuer and the Trustee agrees that the State of
New York shall be the Trustee’s jurisdiction for purposes of Sections 8-110, 9-304 and 9-305 of the
UCC.

     Section 6.17 Notice of Event of Default to the Equityholders. If an Event of Default of which the Trustee has been provided written notice or has actual
knowledge shall have occurred and be continuing, the Trustee shall deliver written notice to each
Equityholder, in accordance with the notice information provided in the Pledge and Security
Agreement to which such Equityholder is party, of the occurrence and continuance of such Event of
Default promptly and in any event within five Business Days of a Responsible Officer of the Trustee
so becoming aware of such Event of Default; provided, that the Trustee shall not be deemed
to have any fiduciary duty to any Equityholder by reason of this Section 6.17, and the Trustee
shall not be liable to any Equityholder for any failure to comply with this Section 6.17.

ARTICLE VII

SUCCESSOR TRUSTEES, REGISTRARS, PAYING AGENTS AND CALCULATION AGENTS

     Section 7.1 Resignation and Removal of Trustee, Registrar, Paying Agent or Calculation Agent. Any
of the Trustee, the Registrar, the Paying Agent and the Calculation Agent may resign as to all or
any of the classes of Notes at any time without cause by giving at least 30 days’ prior written
notice to the Issuer, the Servicer and the Noteholders. Noteholders of a majority of the
Outstanding Principal Balance of any class of Notes may at any time remove one or more of the
Trustee, the Registrar, the Paying Agent and the Calculation Agent as to such class without cause,
with the consent of the Issuer (such consent not to be unreasonably withheld) if no Event of
Default shall have occurred and be continuing, by an instrument in writing delivered to the Issuer,
the Servicer and the Trustee, Registrar, Paying Agent or Calculation Agent being removed. In
addition, the Issuer may remove the Trustee, the Registrar, the Paying Agent or the Calculation
Agent as to any class of Notes if (a) such Trustee, Registrar, Paying Agent or Calculation Agent
fails to comply with Section 310 of the Trust Indenture Act (as if the Trust Indenture Act applied
to this Indenture) after written request therefor by the Issuer or the Noteholders of the related
class who have been bona fide Noteholders for at least six months, (b) such Trustee, Registrar,
Paying Agent or Calculation Agent fails to comply with Section 7.2(d) or any other provision
hereof, (c) such Trustee, Registrar, Paying Agent or Calculation Agent is adjudged a bankrupt or an
insolvent, (d) a receiver or public officer takes charge of such Trustee, Registrar, Paying Agent
or Calculation Agent or its property or (e) such Trustee, Registrar, Paying Agent or Calculation
Agent becomes incapable of acting. References to the Trustee, Registrar, Paying Agent and
Calculation Agent in this Indenture include any successor Trustee, Registrar, Paying Agent or
Calculation Agent, as the case may be, as to all or any of the classes of Notes appointed in
accordance with this Article VII. Any resignation or removal of the Trustee, Registrar, Paying
Agent or Calculation Agent pursuant to this Section

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7.1 shall not be effective until a successor
Trustee, Registrar, Paying Agent or Calculation Agent, as the case may be, shall have been duly
appointed and vested as Trustee, Registrar, Paying Agent or Calculation Agent, as the case may be,
pursuant to Section 7.2.

     Section 7.2 Appointment of Successor.

          (a) In the case of the resignation or removal of the Trustee, Registrar, Paying Agent or
Calculation Agent as to any class of Notes under Section 7.1, the Issuer shall promptly
appoint a successor Trustee, Registrar, Paying Agent or Calculation Agent as to such class.
Every successor Trustee, Registrar, Paying Agent or Calculation Agent (i) shall be a national or
state bank or trust company that is authorized by law to perform all the duties imposed upon it by
this Indenture and to exercise corporate trust powers and (ii) shall have (or, in the case of a
corporation included in a bank holding company system, the related bank holding company shall have)
a combined capital and surplus of at least $50,000,000 as set forth in its (or its related bank
holding company’s) most recent published annual report of condition. If a successor Trustee,
Registrar, Paying Agent or Calculation Agent as to any class of Notes shall not have been appointed
and accepted its appointment hereunder within 60 days after the Trustee, Registrar, Paying Agent or
Calculation Agent, as the case may be, gives notice of resignation as to such class, the retiring
Trustee, Registrar, Paying Agent or Calculation Agent, as the case may be, the Issuer, the Servicer
or a majority of the Outstanding Principal Balance of such class of Notes may petition any court of
competent jurisdiction for the appointment of a successor Trustee, Registrar, Paying Agent or
Calculation Agent as to such class.

          (b) Any successor Trustee, Registrar, Paying Agent or Calculation Agent as to any class of
Notes, however appointed, shall execute and deliver to the Issuer, the Servicer and the predecessor
Trustee, Registrar, Paying Agent or Calculation Agent as to such class an instrument accepting such
appointment, and thereupon such successor Trustee, Registrar, Paying Agent or Calculation Agent,
without further act, shall become vested with all the estates, properties, rights, powers, duties
and trusts of such predecessor Trustee, Registrar, Paying Agent or Calculation Agent hereunder in
the trusts hereunder applicable to it with like effect as if originally named the Trustee,
Registrar, Paying Agent or Calculation Agent as to such class herein; provided, that, upon
the written request of such successor Trustee, Registrar, Paying Agent or Calculation Agent, such
predecessor Trustee, Registrar, Paying Agent or Calculation Agent shall, upon payment of all
amounts due and owing to it, execute and deliver an instrument transferring to such successor
Trustee, Registrar, Paying Agent or Calculation Agent, upon the trusts herein expressed applicable
to it, all the estates, properties, rights, powers and trusts of such predecessor Trustee,
Registrar, Paying Agent or Calculation Agent, and such predecessor Trustee, Registrar, Paying Agent
or Calculation Agent shall duly assign, transfer, deliver and pay over to such successor Trustee,
Registrar, Paying Agent or Calculation Agent all moneys or other property then held by such
predecessor Trustee, Registrar, Paying Agent or Calculation Agent hereunder solely for the benefit
of such class of Notes.

          (c) If a successor Trustee, Registrar, Paying Agent or Calculation Agent is appointed with
respect to one or more (but not all) classes of the Notes, the Issuer, the predecessor Trustee,
Registrar, Paying Agent or Calculation Agent and each successor Trustee, Registrar, Paying Agent or
Calculation Agent with respect to each class of Notes shall execute and deliver an indenture
supplemental hereto that shall contain such provisions as shall be

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deemed necessary or desirable to
confirm that all the rights, powers, trusts and duties of the predecessor Trustee, Registrar,
Paying Agent or Calculation Agent with respect to the classes of Notes as to which the predecessor
Trustee, Registrar, Paying Agent or Calculation Agent is not retiring shall continue to be vested
in the predecessor Trustee, Registrar, Paying Agent or Calculation Agent, and shall add to or
change any of the provisions of this Indenture as shall be necessary to provide for or facilitate
the administration of the Notes hereunder by more than one Trustee, Registrar, Paying Agent or
Calculation Agent.

          (d) Each Trustee, Registrar, Paying Agent or Calculation Agent shall be an Eligible
Institution and shall meet the Eligibility Requirements and the requirements of Section 6.9, if
there be such an institution willing, able and legally qualified to perform the duties of a
Trustee, Registrar, Paying Agent or Calculation Agent hereunder.

          (e) Any Person into which the Trustee, Registrar, Paying Agent or Calculation Agent may be
merged or converted or with which it may be consolidated, or any Person resulting from any merger,
conversion or consolidation to which the Trustee, Registrar, Paying Agent or Calculation Agent
shall be a party, or any Person to which all or substantially all of the corporate trust business
of the Trustee, Registrar, Paying Agent or Calculation Agent (including the administration of the
trust created by this Indenture) may be transferred, shall, subject to the terms of Section 7.2(c),
be the Trustee, Registrar, Paying Agent or Calculation Agent, as the case may be, under this
Indenture without the execution or filing of any paper with any party hereto or any further act on
the part of any party hereto, except where an instrument of transfer or assignment is required by
law to effect such succession, anything herein to the contrary notwithstanding.

ARTICLE VIII

INDEMNITY

     Section 8.1 Indemnity. The Issuer shall indemnify and defend the Trustee (and its officers,
directors, managers, employees and agents) for, and hold it harmless from and against, and
reimburse the Trustee for, any loss, liability or expense incurred by it without bad faith, gross
negligence or willful misconduct on its part in connection with the acceptance or administration of
this Indenture and its performance of its duties under this Indenture and the Notes or any other
Transaction Document, including the costs and expenses of defending itself against any claim or
liability and of complying with any process served upon it or any of its officers in connection
with the exercise or performance of any of its powers or duties, and hold it harmless against any
loss, liability or reasonable expense incurred without bad faith, gross negligence or willful
misconduct on its part, arising out of or in connection with actions taken or omitted to be taken
in reliance on any Officer’s Certificate furnished hereunder, or the failure to furnish any such
Officer’s Certificate required to be furnished hereunder. The Trustee shall notify the Issuer
promptly of any claim asserted against the Trustee for which it may seek indemnity;
provided, however, that failure to provide such notice shall not invalidate any
right to indemnity hereunder. The Issuer shall defend any such claim and the Trustee shall
cooperate in the defense thereof. The Trustee may have separate counsel and the Issuer shall pay
the reasonable fees and expenses of one separate outside counsel for the Trustee. The Issuer need
not pay for any settlements made without its consent; provided, that such consent shall not
be unreasonably withheld or delayed. The Issuer need not reimburse any expense or provide any

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indemnity against any loss, liability or expense incurred by the Trustee through bad faith, gross
negligence or willful misconduct.

     Section 8.2 Noteholders’ Indemnity. The Trustee shall be entitled, subject to such Trustee’s duty
during a Default to act with the standard of care required under this Indenture, to be indemnified
by the Noteholders of any
class of Notes before proceeding to exercise any right or power under this Indenture or any
other Transaction Document at the request or Direction of such Noteholders.

     Section 8.3 Survival. The provisions of Section 8.1 and Section 8.2 shall survive the termination
of this Indenture or the earlier resignation or removal of the Trustee.

ARTICLE IX

MODIFICATION

     Section 9.1 Modification with Consent of Noteholders. Subject to Section 3.7(b), with the consent
of Noteholders of a majority of the Outstanding Principal Balance of the Notes (voting or acting as
a single class), the Trustee may agree to amend, modify or waive any provision of (or consent to
the amendment, modification or waiver of) this Indenture, the Notes, the Pledge and Security
Agreement or the Servicing Agreement; provided, however, that if there shall be
Notes of more than one class Outstanding and if a proposed amendment, modification, consent or
waiver shall directly affect the rights of Noteholders of one or more, but less than all, of such
classes, then the consent only of the Noteholders of a majority of the Outstanding Principal
Balance of each affected class of Notes, each voting or acting as a single class, shall be
required; provided, further, however, that no such amendment, modification,
consent or waiver may, without the consent of Noteholders of 100% of the Outstanding Principal
Balance of the class of Notes affected thereby:

          (a) reduce the percentage of Noteholders of any such class of Notes required to take or
approve any action hereunder or thereunder;

          (b) reduce the amount or change the time of payment of any amount owing or payable with
respect to any such class of Notes (including pursuant to any Redemption) or change the rate of
interest or change the manner of calculation of interest payable with respect to any such class of
Notes;

          (c) alter or modify in any adverse respect the provisions of this Indenture with respect
to the Collateral for the Notes, the provisions of the Pledge and Security Agreement with respect
to the related Issuer Pledged Collateral for the Notes or the manner of payment or the order of
priority in which payments or distributions hereunder will be made as between the Noteholders of
such Notes and the Issuer or as among the Noteholders (including pursuant to Section 3.7) (except,
with respect to Subordinated Notes or as among classes of Subordinated Notes, alterations or
modifications to Section 3.7(a)(vi), at the time such Subordinated Notes are established, provided
such alterations or modifications do not change the order of priority as between the Class A Notes
and the Subordinated Notes);

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          (d) consent to any assignment of the Issuer’s rights to a party other than the Trustee for
the benefit of the Noteholders;

          (e) alter the provisions relating to the Interest Reserve Account in a manner adverse to
any Noteholder; or

          (f) increase the amount of Seller Payments as a percentage of Royalties under Section 3.4;

provided, that the Noteholders of a majority of the Outstanding Principal Balance of the
Senior Class of Notes, by written notice to the Trustee, may waive any Default or Event of Default
to the extent provided in Section 4.5.

     It shall not be necessary for the consent of the Noteholders under this Section 9.1 to approve
the particular form of any proposed amendment or waiver, but it shall be sufficient if such consent
approves the substance thereof. Any such modification approved by the required Noteholders of any
class of Notes will be binding on the Noteholders of the relevant class of Notes and each party to
this Indenture.

     After an amendment under this Section 9.1 becomes effective, the Issuer or, at the direction
of the Issuer, the Trustee shall mail to the Noteholders a notice briefly describing such
amendment. Any failure of the Issuer or the Trustee to mail such notice, or any defect therein,
shall not, however, in any way impair or affect the validity of any such amendment.

     After an amendment under this Section 9.1 becomes effective, it shall bind every Noteholder,
whether or not notation thereof is made on any Note held by such Noteholder.

     Section 9.2 Modification Without Consent of Noteholders. Subject to Section 3.7(b), the Trustee
may, without the consent of any Noteholder, agree to amend, modify or waive any provision of (or
consent to the amendment, modification or waiver of) this Indenture, the Notes, the Pledge and
Security Agreement or the Servicing Agreement to:

          (a) establish the terms of any Refinancing Notes or Subordinated Notes pursuant to Section
2.15 and Section 2.16, respectively (including, with respect to Subordinated Notes or as among
classes of Subordinated Notes, modifications to Section 3.7(a)(vi));

          (b) evidence the succession of a successor to the Trustee, Registrar or Calculation Agent,
the removal of the Trustee, Registrar or Calculation Agent or the appointment of any separate or
additional trustee or trustees or co-trustees and to define the rights, powers, duties and
obligations conferred upon any such separate trustee or trustees or co-trustees;

          (c) correct, confirm or amplify the description of any property at any time subject to the
lien of this Indenture or to convey, transfer, assign, mortgage or pledge any property to or with
the Trustee;

          (d) cure any ambiguity in or correct or supplement any defective or inconsistent provision
of this Indenture, the Notes, the Pledge and Security Agreement or the Servicing

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Agreement in any
manner that will not adversely affect the interests of the Noteholders in any material respect as
confirmed in an Officer’s Certificate of the Issuer;

          (e) grant or confer upon the Trustee for the benefit of the Noteholders any additional
rights, remedies, powers, authority or security that may be lawfully granted or conferred and that
are not contrary to this Indenture;

          (f) add to the covenants or agreements to be observed by the Issuer, which are not
contrary to this Indenture, or to add Events of Default for the benefit of the Noteholders;

          (g) comply with the requirements of the SEC or any other regulatory body or any Applicable
Law;

          (h) effect any indenture supplemental hereto or any other amendment, modification,
supplement, waiver or consent with respect to this Indenture, the Notes, the Pledge and Security
Agreement or the Servicing Agreement; provided, that such indenture supplemental hereto,
amendment, modification, supplement, waiver or consent will not adversely affect the interests of
the Noteholders in any material respect as confirmed in an Officer’s Certificate of the Issuer; or

          (i) reduce, waive or eliminate the amount of Seller Payments as a percentage of Royalties
under Section 3.4.

     After an amendment under this Section 9.2 becomes effective, the Issuer or, at the direction
of the Issuer, the Trustee shall mail to the Noteholders a notice briefly describing such
amendment. Any failure of the Issuer or the Trustee to mail such notice, or any defect therein,
shall not, however, in any way impair or affect the validity of any such amendment.

     After an amendment under this Section 9.2 becomes effective, it shall bind every Noteholder,
whether or not notation thereof is made on any Note held by such Noteholder.

     Section 9.3 Subordination; Priority of Payments. The subordination provisions contained in
Article X may not be amended or modified without the consent of Noteholders of 100% of the
Outstanding Principal Balance of the class of Notes affected thereby. In no event shall the
provisions set forth in Section 3.7 relating to the priority of payment of Expenses be amended or
modified.

     Section 9.4 Execution of Amendments by Trustee. In executing, or accepting the additional trusts
created by, any amendment or modification to this Indenture permitted by this Article IX or the
modifications thereby of the trusts created by this Indenture, the Trustee shall be entitled to
receive, and shall be fully protected in relying upon, an Officer’s Certificate and an Opinion of
Counsel stating that the execution of such amendment is authorized or permitted by this Indenture.
The Trustee may, but shall not be obligated to, enter into any such amendment that affects the
Trustee’s own rights, duties or immunities under this Indenture or otherwise.

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ARTICLE X

SUBORDINATION

     Section 10.1 Subordination of the Notes.

          (a) Each of the Issuer and the Trustee (on behalf of the Noteholders) covenants and
agrees, and each Noteholder, by its acceptance of a Note, covenants and agrees, that the Notes of
each class will be issued subject to the provisions of this Article X. Each Noteholder, by its
acceptance of a Note, further agrees that all amounts payable on any Note will, to the extent
provided in Section 3.7 and in the manner set forth in this Article X, be subordinated in right of
payment to the prior payment in full of all Taxes owed by the Issuer (if any), all Expenses payable
to the Service Providers pursuant to this Indenture and the other Transaction Documents. Each
Noteholder of a Subordinated Note, by its acceptance of a Subordinated Note, further agrees that
all amounts payable on any Subordinated Note will, to the extent provided in Section 3.7 and in the
manner set forth in this Article X, be subordinated in right of payment to the payment in full of
the Class A Notes. Any claim to payment so stated to be subordinated is referred to as a
“Subordinated Claim”; each claim to payment to which another claim to payment is a
Subordinated Claim is referred to as a “Senior Claim” with respect to such Subordinated
Claim.

          (b) If, prior to the payment in full of all Senior Claims then due and payable, the
Trustee or any Noteholder of a Subordinated Claim shall have received any payment or distribution
in respect of such Subordinated Claim in excess of the amount to which such Noteholder was then
entitled under Section 3.7, then such payment or distribution shall be received and held in trust
by such Person and paid over or delivered to the Trustee for application as provided in Section
3.7.

          (c) If any Service Provider, any Equityholder, the Trustee or any Noteholder of any Senior
Claim receives any payment in respect of any Senior Claim that is subsequently invalidated,
declared preferential, set aside and/or required to be repaid to a trustee, receiver or other
party, then, to the extent such payment is so invalidated, declared preferential, set aside and/or
required to be repaid, such Senior Claim shall be revived and continue in full force and effect and
shall be entitled to the benefits of this Article X, all as if such payment had not been received.

          (d) The Trustee (on its own behalf and on behalf of the Noteholders) and the Issuer each
confirm that the payment priorities specified in Section 3.7 shall apply in all circumstances.

          (e) Each Noteholder, by its acceptance of a Note, authorizes and expressly directs the
Trustee on its behalf to take such action as may be necessary or appropriate to effectuate the
subordination provided in this Article X, and appoints the Trustee its attorney-in-fact for such
purposes, including, in the event of any dissolution, winding-up, liquidation or reorganization of
the Issuer (whether in bankruptcy, insolvency, receivership, reorganization or similar proceedings
or upon an assignment for the benefit of creditors or otherwise), any actions tending towards
liquidation of the property and assets of the Issuer or the filing of a claim for the unpaid
balance of its Notes in the form required in those proceedings.

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          (f) If payment on the Notes is accelerated as a result of an Event of Default, the Issuer
shall promptly notify the holders of the Senior Claims of such acceleration.

          (g) After all Senior Claims are paid in full and until the Subordinated Claims are paid in
full, and to the extent that such Senior Claims shall have been paid with funds that would, but for
the subordination pursuant to this Article X, have been paid to and retained by such holders of
Subordinated Claims, the holders of Subordinated Claims shall be subrogated to the rights of
holders of Senior Claims to receive payments applicable to Senior Claims. A payment made under
this Article X to holders of Senior Claims that otherwise would have been made to the holders of
Subordinated Claims is not, as between the Issuer and the holders of Subordinated Claims, a payment
by the Issuer.

          (h) No right of any holder of any Senior Claim to enforce the subordination of any
Subordinated Claim shall be impaired by an act or failure to act by the Issuer or the Trustee or by
any failure by either the Issuer or the Trustee to comply with this Indenture.

          (i) Each Noteholder by accepting a Note acknowledges and agrees that the foregoing
subordination provisions are, and are intended to be, an inducement and a consideration to each
holder of any Senior Claim, whether such Senior Claim was created or acquired before or after the
issuance of such Noteholder’s claim, to acquire and continue to hold such Senior Claim, and such
holder of any Senior Claim shall be deemed conclusively to have relied on such subordination
provisions in acquiring and continuing to hold such Senior Claim. Each holder of a Subordinated
Claim agrees to comply with the provisions of Article IV.

ARTICLE XI

DISCHARGE OF INDENTURE

     Section 11.1 Discharge of Indenture.

          (a) When (i) all outstanding Secured Obligations have been satisfied and the Issuer
delivers to the Trustee all Outstanding Notes (other than Notes replaced pursuant to Section 2.8)
for cancellation or (ii) all Outstanding Notes have become due and payable, whether at maturity or
as a result of the mailing of a notice of an Optional Redemption pursuant to Section 3.9(b) or any
other Redemption pursuant to Section 3.9(c), in each case that is subject to Section 3.10(c), and
the Issuer irrevocably deposits in the Redemption Account funds sufficient to pay all remaining
Expenses accrued and payable through such date and to pay all principal of and interest and Premium
(if any) on Outstanding Notes at maturity or upon redemption all Outstanding Notes, including
interest and any Premium thereon to maturity or the Redemption Date (other than Notes replaced
pursuant to Section 2.8), and if in either case the Issuer pays all other sums payable hereunder by
the Issuer, then this Indenture shall, subject to Section 11.1(b), cease to be of further effect
and the Security Interest granted to the Trustee hereunder in the Collateral and the Indenture
Estate shall terminate. The Trustee shall acknowledge satisfaction and discharge of this
Indenture, file all UCC termination statements and similar documents prepared by the Issuer and
take other actions in order to terminate the Security Interest, on demand of the Issuer accompanied
by an Officer’s Certificate and an Opinion of Counsel, at the cost and expense of the Issuer, to
the effect that any conditions precedent to a discharge of this Indenture have been met.

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          (b) Notwithstanding Section 11.1(a), the Issuer’s obligations in Section 3.7(b) and
Section 8.1 and the Trustee’s obligations in Section 12.13 and Section 12.14 shall survive the
satisfaction and discharge of this Indenture.

     Section 11.2 Release of Security Interest in Certain Cash Collateral. Upon distribution or
transfer of (a) cash amounts permitted to be distributed or transferred by Article III and (b) cash
proceeds from the Notes issued in accordance with this Indenture, the security interest in such
cash amounts or such cash proceeds, as the case may be, shall terminate, and such item(s) of
Collateral shall be released therefrom, immediately upon such distribution or transfer, without any
further action by the Trustee; provided, however, that such release shall not apply
to any other Collateral.

ARTICLE XII

MISCELLANEOUS

     Section 12.1 Right of Trustee to Perform. If the Issuer for any reason fails to observe or
punctually to perform any of its obligations to the Trustee, whether under this Indenture, under
any of the other Transaction Documents or otherwise, the Trustee shall have the power (but shall
have no obligation), on behalf of or in the name of the Issuer or otherwise, to perform such
obligations or cause performance of such obligations and to take any steps that the Trustee may, in
its absolute discretion, consider appropriate with a view to remedying, or mitigating the
consequences of, such failure by the Issuer, in which case the reasonable expenses of the Trustee,
including the reasonable fees and expenses of its counsel, incurred in connection therewith shall
be payable by the Issuer under Section 8.1; provided, that no exercise or failure to
exercise this power by the Trustee shall in any way prejudice the Trustee’s other rights under this
Indenture or any of the other Transaction Documents.

     Section 12.2 Waiver. Any waiver by any party of any provision of this Indenture or any right,
remedy or option hereunder shall only prevent and estop such party from thereafter enforcing such
provision, right, remedy or option if such waiver is given in writing and only as to the specific
instance and for the specific purpose for which such waiver was given. The failure or refusal of
any party hereto to insist in any one or more instances, or in a course of dealing, upon the strict
performance of any of the terms or provisions of this Indenture by any party hereto or the partial
exercise of any right, remedy or option hereunder shall not be construed as a waiver or
relinquishment of any such term or provision, but the same shall continue in full force and effect.
No failure on the part of the Trustee to exercise, and no delay on its part in exercising, any
right or remedy under this Indenture will operate as a waiver thereof, nor will any single or
partial exercise of any right or remedy preclude any other or further exercise thereof or the
exercise of any other right or remedy. The rights and remedies provided in this Indenture are
cumulative and not exclusive of any rights or remedies provided by law.

     Section 12.3 Severability. In the event that any provision of this Indenture or the application thereof to any
party hereto or to any circumstance or in any jurisdiction governing this Indenture shall, to any
extent, be invalid or unenforceable under any applicable statute, regulation or rule of law, then
such provision shall be deemed inoperative to the extent that it is invalid or unenforceable, and
the remainder of this Indenture, and the application of any such

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invalid or unenforceable provision to the parties, jurisdictions or circumstances other than
to whom or to which it is held invalid or unenforceable, shall not be affected thereby nor shall
the same affect the validity or enforceability of this Indenture. The parties hereto further agree
that the holding by any court of competent jurisdiction that any remedy pursued by the Trustee
hereunder is unavailable or unenforceable shall not affect in any way the ability of the Trustee to
pursue any other remedy available to it.

     Section 12.4 Restrictions on Exercise of Certain Rights. The
Trustee and, during the continuance of a payment Default with respect to the Senior Class of Notes,
the Senior Trustee, except as otherwise provided in Section 4.4, Section 4.9 and Section 4.11, may
sue for recovery or take any other steps for the purpose of recovering any of the obligations
hereunder or any other debts or liabilities whatsoever owing to it by the Issuer. Each of the
Noteholders shall at all times be deemed to have agreed by virtue of the acceptance of the Notes
that only the Trustee and, during the continuance of a payment Default with respect to the Senior
Class of Notes, the Senior Trustee, except as provided in Section 4.4, Section 4.9 and Section
4.11, may take any steps for the purpose of procuring the appointment of an administrative
receiver, examiner, receiver or similar officer or the making of an administration order or for
instituting any bankruptcy, reorganization, arrangement, insolvency, winding-up, liquidation,
composition, examination or any like proceedings under Applicable Law.

     Section 12.5 Notices. All Notices shall be in writing and shall be effective (a) upon receipt when
sent through the mails, registered or certified mail, return receipt requested, postage prepaid,
with such receipt to be effective the date of delivery indicated on the return receipt, (b) upon
receipt when sent by an overnight courier, (c) on the date personally delivered to an authorized
officer of the party to which sent, (d) on the date transmitted by legible telecopier transmission
with a confirmation of receipt or (e) in the case of reports under Article III and any other report
that is of a routine nature, on the date sent by first class mail or overnight courier or
transmitted by legible telecopier transmission, in all cases, with a copy emailed to the recipient
at the applicable address, addressed to the recipient as follows:

if to the Issuer, to:

JPR Royalty Sub LLC

c/o BioCryst Pharmaceuticals, Inc.

4505 Emperor Boulevard, Suite 200

Durham, North Carolina 27703

Attention: General Counsel

Telephone: 919-859-1302

Facsimile: 919-851-1416

Email: abarnes@biocryst.com

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if to the Trustee, the Registrar, the Paying Agent or the Calculation Agent, to:

U.S. Bank National Association

One Federal Street, 3rd Floor

Boston, Massachusetts 02110

Attention: Corporate Trust Services (JPR Royalty Sub LLC / BioCryst)

Telephone: 617-603-6553

Facsimile: 617-603-6683

A copy of each notice given hereunder to any party hereto shall also be given to each of the other
parties hereto. Each party hereto may, by notice given in accordance herewith to each of the other
parties hereto, designate any further or different address to which subsequent Notices shall be
sent.

     Section 12.6 Assignments. This Indenture shall be a continuing obligation of the Issuer and shall
(a) be binding upon the Issuer and its successors and assigns and (b) inure to the benefit of and
be enforceable by the Trustee and by its successors, transferees and assigns and, as and to the
extent provided in Section 3.7(b), the Equityholders. The Issuer may not assign any of its
obligations under this Indenture or delegate any of its duties hereunder.

     Section 12.7 Application to Court. The Trustee may at any time after the service of an
Acceleration Notice apply to any court of competent jurisdiction for an order that the terms of
this Indenture be carried into execution under the direction of such court and for the appointment
of a Receiver of the Collateral or any part thereof and for any other order in relation to the
administration of this Indenture as the Trustee shall deem fit, and it may assent to or approve any
application to any court of competent jurisdiction made at the instigation of any of the
Noteholders and shall be indemnified by the Issuer against all costs, charges and expenses incurred
by it in relation to any such application or proceedings.

     Section 12.8 GOVERNING LAW. THIS INDENTURE SHALL BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH
THE INTERNAL SUBSTANTIVE LAWS OF THE STATE OF NEW
YORK WITHOUT REFERENCE TO THE RULES THEREOF RELATING TO CONFLICTS OF LAW OTHER THAN SECTION
5-1401 OF THE GENERAL OBLIGATIONS LAW OF THE STATE OF NEW YORK, AND THE OBLIGATIONS, RIGHTS AND
REMEDIES HEREUNDER SHALL BE DETERMINED IN ACCORDANCE WITH SUCH LAWS.

     Section 12.9 Jurisdiction.

          (a) Each of the parties hereto agrees that the U.S. federal and State of New York courts
located in the Borough of Manhattan, The City of New York shall have jurisdiction to hear and
determine any suit, action or proceeding, and to settle any disputes, which may arise out of or in
connection with this Indenture and, for such purposes, submits to the jurisdiction of such courts.
Each of the parties hereto waives any objection that it might now or hereafter have to the U.S.
federal or State of New York courts located in the Borough of Manhattan, The City of New York being
nominated as the forum to hear and determine any suit, action or proceeding, and to settle any
disputes, which may arise out of or in connection with this Indenture and agrees not to

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claim that any such court is not a convenient or appropriate forum. Each of the parties hereto has
irrevocably designated, appointed and empowered the respective Persons named in Exhibit C
as its designee, appointee and agent to receive, accept and acknowledge for and on its behalf, and
its properties, assets and revenues, service of any and all legal process, summons, notices and
documents that may be served in any suit, action or proceeding brought against such party in any
United States or state court arising out of or relating to this Indenture or the Notes. If for any
reason any such designee, appointee and agent hereunder shall cease to be available to act as such,
such party agrees to designate a new designee, appointee and agent in the Borough of Manhattan, The
City of New York on the terms and for the purposes of this Section 12.9 satisfactory to such other
party. Each party further hereby irrevocably consents and agrees to the service of any and all
legal process, summons, notices and documents in any suit, action or proceeding against such party
by serving a copy thereof upon the relevant agent for service of process referred to in this
Section 12.9 (whether or not the appointment of such agent shall for any reason prove to be
ineffective or such agent shall accept or acknowledge such service) or by mailing copies thereof by
registered or certified mail, postage prepaid, to such party at its address specified in or
designated pursuant to this Indenture. Each party agrees that the failure of any such designee,
appointee and agent to give any notice of such service to it shall not impair or affect in any way
the validity of such service or any judgment rendered in any action or proceeding based thereon.
Nothing herein shall in any way be deemed to limit the ability of the Issuer or the Trustee and the
Noteholders, as the case may be, to serve any such legal process, summons, notices and documents in
any other manner permitted by Applicable Law or to obtain jurisdiction over such party or bring
suits, actions or proceedings against such party in such other jurisdictions, and in such manner,
as may be permitted by Applicable Law.

          (b) The submission to the jurisdiction of the courts referred to in Section 12.9(a) shall
not (and shall not be construed so as to) limit the right of the Trustee to take proceedings
against the Issuer in any other court of competent jurisdiction, nor shall the taking of
proceedings in any one or more jurisdictions preclude the taking of proceedings in any other
jurisdiction, whether concurrently or not.

          (c) Each of the parties hereto hereby consents generally in respect of any legal action or
proceeding arising out of or in connection with this Indenture to the giving of any relief
or the issue of any process in connection with such action or proceeding, including the
making, enforcement or execution against any property whatsoever (irrespective of its use or
intended use) of any order or judgment that may be made or given in such action or proceeding.

          (d) If, for the purpose of obtaining a judgment or order in any court, it is necessary to
convert a sum due hereunder to any Noteholder from dollars into another currency, the Issuer has
agreed, and each Noteholder by holding a Note will be deemed to have agreed, to the fullest extent
that they may effectively do so, that the rate of exchange used shall be that at which, in
accordance with normal banking procedures, such Noteholder could purchase dollars with such other
currency in the Borough of Manhattan, The City of New York on the Business Day preceding the day on
which final judgment is given.

          (e) The obligation of the Issuer in respect of any sum payable by it to a Noteholder
shall, notwithstanding any judgment or order in a currency other than dollars (the “Judgment
Currency”), be discharged only to the extent that, on the Business Day following

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receipt by such Noteholder of such security of any sum adjudged to be so due in the Judgment
Currency, such Noteholder may in accordance with normal banking procedures purchase dollars with
the Judgment Currency. If the amount of dollars so purchased is less than the sum originally due
to such Noteholder in the Judgment Currency (determined in the manner set forth in Section
12.9(d)), the Issuer agrees, as a separate obligation and notwithstanding any such judgment, to
indemnify such Noteholder against such loss, and, if the amount of the dollars so purchased exceeds
the sum originally due to such Noteholder, such Noteholder agrees to remit to the Issuer such
excess, provided that such Noteholder shall have no obligation to remit any such excess as long as
the Issuer shall have failed to pay such Noteholder any obligations due and payable under the Notes
of such Noteholder, in which case such excess may be applied to such obligations of the Issuer
under such Notes in accordance with the terms thereof. The foregoing indemnity shall constitute a
separate and independent obligation of the Issuer and shall continue in full force and effect
notwithstanding any such judgment or order as aforesaid.

          (f) EACH OF THE PARTIES HERETO IRREVOCABLY WAIVES ALL RIGHT OF TRIAL BY JURY IN ANY
ACTION, PROCEEDING OR COUNTERCLAIM ARISING OUT OF OR IN CONNECTION WITH THIS INDENTURE OR ANY
MATTER ARISING HEREUNDER.

     Section 12.10 Counterparts. This Indenture may be executed in one or more counterparts by the
parties hereto, and each such counterpart shall be considered an original and all such counterparts
shall constitute one and the same instrument.

     Section 12.11 Table of Contents and Headings. The Table of Contents and headings of the Articles
and Sections of this Indenture have been inserted for convenience of reference only, are not to be
considered a part hereof and shall in no way modify or restrict any of the terms or provisions
hereof.

     Section 12.12 Trust Indenture Act. This Indenture shall not be qualified under the Trust Indenture Act and shall not be
subject to the provisions of the Trust Indenture Act.

     Section 12.13 Confidential Information. The Trustee, in its individual capacity and as Trustee,
agrees and acknowledges that all information (including Confidential Information) provided to the
Trustee by an Equityholder, the Seller or the Issuer may be considered to be proprietary and
confidential information of Counterparty. The Trustee agrees to take all reasonable precautions
necessary to keep such information confidential, which precautions shall be no less stringent than
those that the Trustee employs to protect its own confidential information. The Trustee shall not
disclose to any third party other than as set forth herein, and shall not use for any purpose other
than the exercise of the Trustee’s rights and the performance of its obligations under this
Indenture, any such information without the prior written consent of Counterparty. In addition,
the Trustee agrees to be bound by the provisions of Section 4.2 of the Purchase and Sale Agreement
to the extent it receives confidential information of Counterparty pursuant to Section 3.1 of the
Servicing Agreement or Section 5.3. The Trustee shall limit access to such information received
hereunder to (a) its directors, officers, managers and employees and (b) its legal advisors, to
each of whom disclosure of such information is necessary for the purposes described above;
provided, however, that in each case such party has

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expressly agreed to maintain such information in confidence under terms and conditions
substantially identical to the terms of this Section 12.13.

     The Trustee agrees that Counterparty does not have any responsibility whatsoever for any
reliance on such information by the Trustee or by any Person to whom such information is disclosed
in connection with this Indenture, whether related to the purposes described above or otherwise.
Without limiting the generality of the foregoing, the Trustee agrees that Counterparty makes no
representation or warranty whatsoever to it with respect to such information or its suitability for
such purposes. The Trustee further agrees that it shall not acquire any rights against
Counterparty or any employee, officer, director, manager, representative or agent of Counterparty
(together with Counterparty, “Confidential Parties”) as a result of the disclosure of such
information to the Trustee or to any Noteholder or Beneficial Holder and that no Confidential Party
has any duty, responsibility, liability or obligation to any Person as a result of any such
disclosure.

     In the event the Trustee is required to disclose any such information received hereunder in
order to comply with any laws, regulations or court orders, it may disclose such information only
to the extent necessary for such compliance; provided, however, that it shall give
Counterparty and the Issuer reasonable advance written notice of any such court proceeding in which
such disclosure may be required pursuant to a court order so as to afford Counterparty a full and
fair opportunity to oppose the issuance of such order and to appeal therefrom and shall cooperate
reasonably with Counterparty in opposing such order and in securing confidential treatment of any
such information to be disclosed and/or obtaining a protective order narrowing the scope of such
disclosure.

     The Trustee agrees that Counterparty is an express third-party beneficiary of the provisions
of this Section 12.13.

     Each of the Calculation Agent, the Paying Agent and the Registrar agrees to be bound by this
Section 12.13 to the same extent as the Trustee.

     Section 12.14
Limited Recourse. Each of the parties hereto accepts that the enforceability against
the Issuer of the obligations of the Issuer hereunder and under the Notes shall be limited to the
assets of the Issuer, whether tangible or intangible, real or personal (including the Collateral)
and the proceeds thereof. Once all such assets have been realized upon and such assets (and
proceeds thereof) have been applied in accordance with Article III, any outstanding obligations of
the Issuer shall be extinguished. For the avoidance of doubt, this Section 12.14 does not affect
the obligations of the Equityholders under the Pledge and Security Agreement or the ability of the
Trustee or any Noteholder to exercise any rights or remedies it may have under the Pledge and
Security Agreement. Each of the parties hereto further agrees that it shall take no action against
any employee, director, officer or administrator of the Issuer, an Equityholder or the Trustee in
relation to this Indenture; provided, that nothing herein shall limit the Issuer (or its
permitted successors or assigns, including any party hereto that becomes such a successor or
assign) from pursuing claims, if any, against any such Person. The provisions of this Section
12.14 shall survive termination of this Indenture; provided, further, that the
foregoing shall not in any way limit, impair or otherwise affect any rights of the Trustee or the
Noteholders to proceed against any such Person (a) for intentional and willful fraud or

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intentional and willful misrepresentations on the part of or by such Person or (b) for the
receipt of any distributions or payments to which the Issuer or any successor in interest is
entitled, other than distributions expressly permitted pursuant to this Indenture and the other
Deal Documents.

     Section 12.15 Tax Matters.

          (a) The Issuer has entered into this Indenture, and the Notes will be issued, with the
intention that, for all Tax purposes, the Notes will qualify as indebtedness. The Issuer, by
entering into this Indenture, and each Noteholder and Beneficial Holder, agree to treat the Notes
as debt for all Tax purposes.

          (b) The Issuer shall not be obligated to pay any additional amounts to the Noteholders or
Beneficial Holders as a result of any withholding or deduction for, or on account of, any present
or future Taxes imposed on payments in respect of the Notes. If a Global Note is issued, in
accordance with the procedures of DTC, the Issuer shall (or shall direct the Trustee in writing to)
request the Notes to be coded as eligible for the “portfolio interest exemption”. Unless otherwise
required by Applicable Law, if Definitive Notes are issued, so long as a Person shall have
delivered to the Issuer a properly completed IRS Form W-9, IRS Form W-8BEN, IRS Form W-8ECI or
other applicable IRS form or, in the case of a Person claiming the exemption from U.S. federal
withholding tax under Section 871(h) of the Code or Section 881(c) of the Code with respect to
payments of “portfolio interest”, the appropriate properly completed IRS form together with a
certificate substantially in the form of Exhibit K, neither the Issuer nor the Trustee
shall withhold Taxes on payments of interest made to any such Person. Any such IRS Form W-8BEN
shall specify whether the Noteholder or Beneficial Holder to whom the form relates is entitled to
the benefits of any applicable income tax treaty.

          (c) Provided that the Issuer complies with Section 5.2(u), Section 12.15(a) and Section
12.15(b), if Definitive Notes are issued, (i) if any withholding Tax is imposed on the Issuer’s
payment under the Notes to any Noteholder or Beneficial Holder, such Tax shall reduce the amount
otherwise distributable to such Noteholder or Beneficial Holder, as the case may be, (ii) the
Trustee is hereby authorized and directed to retain from amounts otherwise distributable to any
Noteholder or Beneficial Holder sufficient funds for the payment of any withholding Tax that is
legally owed by the Issuer (but such authorization shall not prevent the Trustee from contesting
any such withholding Tax in appropriate proceedings and withholding payment of such Tax, if
permitted by Applicable Law, pending the outcome of such proceedings) and (iii) the amount of any
withholding Tax imposed with respect to any Noteholder or Beneficial Holder shall be treated as
cash distributed to such Noteholder or Beneficial Holder, as the case may be, at the time it is
withheld by the Trustee and remitted to the appropriate taxing authority. Provided that the Issuer
complies with Section 5.2(u), Section 12.15(a) and Section 12.15(b), if there is a possibility that
withholding Tax is payable with respect to a payment under the Notes, the Trustee may (but shall
have no obligation to) withhold such amounts in accordance with this Section 12.15. Nothing herein
shall impose an obligation on the part of the Trustee to determine the amount of any Tax or
withholding obligation on the part of the Issuer or in respect of the Notes.

83

 

     Section 12.16 Waiver. The Issuer waives any right to contest or otherwise assert
that the Purchase and Sale Agreement is other than a true, absolute and irrevocable sale and
assignment by the Seller to the Issuer of the Purchased Assets under Applicable Law.

     Section 12.17 Distribution Reports. Each party hereto acknowledges and agrees that the Trustee may
effect delivery of any Distribution Report (including the materials accompanying such Distribution
Report) by making such Distribution Report and accompanying materials available by posting such
Distribution Report and accompanying materials on IntraLinks or a substantially similar electronic
transmission system; provided, however, that, upon written notice to the Trustee,
any Noteholder may decline to receive such Distribution Report and accompanying materials via
IntraLinks or a substantially similar electronic transmission system, in which case such
Distribution Report and accompanying materials shall be provided as otherwise set forth in the Deal
Documents. Subject to the conditions set forth in the proviso in the immediately preceding
sentence, nothing in this Section 12.17 shall prejudice the right of the Trustee to make such
Distribution Report and accompanying materials available in any other manner specified in the Deal
Documents.

[SIGNATURE PAGE FOLLOWS]

84

 

     IN WITNESS WHEREOF, the parties hereto have executed this Indenture to be duly executed, all
as of the date first written above.

	 	 	 	 	 
	 	JPR ROYALTY SUB LLC,
as Issuer

 	 
	 	By:  	BioCryst Pharmaceuticals, Inc., its Manager
 	 
	 
	 	 	 
	 	By:  	/s/ Stuart Grant
 	 
	 	 	Name:  	Stuart Grant 	 
	 	 	Title:  	Chief Financial Officer 	 
	 

	 	 	 	 	 
	 	U.S. BANK NATIONAL ASSOCIATION,
as Trustee

 	 
	 	By:  	/s/ Alison D. B. Nadeau
 	 
	 	 	Name:  	Alison D.B. Nadeau 	 
	 	 	Title:  	Vice President 	 

 

 

	 	 	 	 	 

ANNEX A

RULES OF CONSTRUCTION AND DEFINED TERMS

Unless the context otherwise requires, in this Annex A and each Transaction Document (or
other document) to which this Annex A is attached:

	(a)	 	A term has the meaning assigned to it and an accounting term not otherwise defined has
the meaning assigned to it in accordance with GAAP.

	(b)	 	Unless otherwise defined, all terms used herein or therein that are defined in the UCC
shall have the meanings stated in the UCC.

	(c)	 	Words of the masculine, feminine or neuter gender shall mean and include the correlative
words of other genders, and words in the singular shall include the plural, and vice versa.

	(d)	 	The terms “include”, “including” and similar terms shall be construed as if followed by
the phrase “without limitation”.

	(e)	 	References to an agreement or other document include references to such agreement or
document as amended, restated, reformed, supplemented or otherwise modified in accordance with
the terms thereof and include any Annexes, Exhibits and Schedules attached thereto, and the
provisions thereof apply to successive events and transactions.

	(f)	 	References to any statute or other legislative provision shall include any statutory or
legislative modification or re-enactment thereof, or any substitution therefor.

	(g)	 	References to any Person shall be construed to include such Person’s successors and
permitted assigns.

	(h)	 	The word “will” shall be construed to have the same meaning and effect as the word
“shall”.

	(i)	 	The words “hereof”, “herein”,
“hereunder” and similar terms when used in this Annex A or any
Transaction Document (or other document) shall refer to this Annex A or such
Transaction Document (or other document) as a whole and not to any particular provision hereof
or thereof, and Article, Section, Annex, Schedule and Exhibit references herein and therein
are references to Articles and Sections of, and Annexes, Schedules and Exhibits to, the
relevant Transaction Document (or other document) unless otherwise specified.

	(j)	 	In the computation of a period of time from a specified date to a later specified date,
the word “from” means “from and including” and each of the
words “to” and “until” means ”to but excluding”.

	(k)	 	References to a class of Notes shall be to the Original Class A Notes, to a class of
Subordinated Notes or to a class of Refinancing Notes, as applicable.

 

 

	(l)	 	References to the Notes include the terms and conditions in the relevant Transaction
Document (or other document) applicable to the Notes, and any reference to any amount of money
due or payable by reference to the Notes shall include any sum covenanted to be paid by the
Issuer under the relevant Transaction Document (or other document) in respect of the Notes.

	(m)	 	References to any action, remedy or method of judicial proceeding for the enforcement of
the rights of creditors or of security shall be deemed to include, in respect of any
jurisdiction other than the State of New York, references to such action, remedy or method of
judicial proceeding for the enforcement of the rights of creditors or of security available or
appropriate in such jurisdiction as shall most nearly approximate such action, remedy or
method of judicial proceeding described or referred to in the relevant Transaction Document
(or other document).

	(n)	 	Where any payment is to be made, any funds are to be applied or any calculation is to be
made under any Transaction Document (or other document) on a day that is not a Business Day,
unless any Transaction Document (or other document) otherwise provides, such payment shall be
made, such funds shall be applied and such calculation shall be made on the next succeeding
Business Day, and payments shall be adjusted accordingly, including interest unless otherwise
specified; provided, however, that no interest shall accrue in respect of any
payments made on Fixed Rate Notes on that next succeeding Business Day.

	(o)	 	References to any Calculation Date or Relevant Calculation Date, in each case that would
be prior to the first Calculation Date that follows the Closing Date, shall be deemed to refer
to the Closing Date.

	(p)	 	Any reference herein to a term that is defined by reference to its meaning in the
Counterparty License Agreement or the UAB Agreement shall refer to such term’s meaning in the
Counterparty License Agreement or the UAB Agreement, as the case may be, as in existence on
the date of the relevant Transaction Document (or other document) to which this Annex
A is attached (and not to any new, substituted or amended version thereof).

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     “144A Global Note” has the meaning set forth in Section 2.1(b) of the Indenture.

     “Acceleration Default” means any Event of Default of the type described in Section
4.1(f) of the Indenture.

     “Acceleration Notice” means a written notice given after the occurrence and
continuation of an Event of Default to the Issuer by the Senior Trustee pursuant to Section 4.2 of
the Indenture declaring all Outstanding principal of and accrued and unpaid interest on the Notes
to be immediately due and payable.

     “Accounts” means the Collection Account, the Redemption Account, the Escrow Account,
the Capital Account, the Interest Reserve Account and any other account established pursuant to
Section 3.1 of the Indenture.

     “Act” has the meaning set forth in Section 1.3(a) of the Indenture.

     “Actual Beneficial Holder List” has the meaning set forth in Section 2.5(d) of the
Indenture.

     “Additional Interest” means, with respect to the Notes, interest accrued on the amount
of any interest and Premium, if any, in respect of such Notes that is not paid when due at the
Stated Rate of Interest of such Notes for each Interest Accrual Period until any such unpaid
interest or Premium is paid in full, compounded annually on each Payment Date, to the fullest
extent permitted by Applicable Law.

     “Affiliate” means, with respect to any Person, any other Person that, directly or
indirectly, controls, is controlled by or is under common control with such Person or is a
director, officer or manager of such Person. For purposes of this definition, “control” of
a Person means the possession, directly or indirectly, of the power to direct or cause the
direction of the management and policies of such Person, whether through the ownership of Voting
Securities, by contract or otherwise, and the terms “controlled” and “controlling”
have meanings correlative to the foregoing.

     “Agent Members” has the meaning set forth in Section 2.10(a) of the Indenture.

     “Applicable Law” means, with respect to any Person, all laws, rules, regulations and
orders of Governmental Authorities applicable to such Person or any of its properties or assets.

     “Applicants” has the meaning set forth in Section 6.13 of the Indenture.

     “Approved Holder List” has the meaning set forth in Section 2.5(d) of the Indenture.

     “Audit Expenses” has the meaning set forth in Section 6.14(b) of the Indenture.

     “Authorized Agent” means, with respect to the Notes, any authorized Calculation Agent,
Paying Agent or Registrar acting as such for the Notes.

A-3

 

     “Available Collections Amount” means, for any Payment Date, the sum of (a) the amount
of U.S. dollars on deposit in the Collection Account as of the Calculation Date immediately
preceding such Payment Date and (b) the amount of any net investment income on amounts on deposit
in the Accounts (other than the Capital Account) as of such Calculation Date.

     “Bankruptcy Code” means Title 11 of the United States Code, as amended.

     “Beneficial Holder” means any Person that holds a Beneficial Interest in any Global
Note through an Agent Member.

     “Beneficial Interest” means any beneficial interest in any Global Note, whether held
directly by an Agent Member or held indirectly through an Agent Member’s beneficial interest in
such Global Note.

     “Bill of Sale” means that certain bill of sale dated as of the Closing Date executed
by the Seller and the Issuer.

     “Business Day” means (a) any day that is not a Saturday, Sunday or other day on which
commercial banks in New York City are authorized or required by Applicable Law to remain closed or
a day on which the Corporate Trust Office is closed for business and (b) for purposes of
calculating any amounts at the London interbank offered rate and related calculations relative to
the making, continuing, prepaying or repaying of Indebtedness in respect thereof, any day that is a
Business Day described in clause (a) that is also a day on which dealings in dollars are carried on
in the London interbank market.

     “Calculation Agent” means U.S. Bank National Association, a national banking
association, as Calculation Agent under the Indenture, and any successor appointed pursuant to
Section 2.3 of the Indenture.

     “Calculation Date” means, for any Payment Date, the fifth Business Day preceding such
Payment Date.

     “Calculation Date Information” means, with respect to any Calculation Date, the
information provided by the Servicer under Section 3.1(c) of the Servicing Agreement with respect
to such Calculation Date.

     “Calculation Report” has the meaning set forth in Section 3.5(b) of the Indenture.

     “Capital Account” has the meaning set forth in Section 3.1(a) of the Indenture.

     “Capital Securities” means, with respect to any Person, all shares, interests,
participations or other equivalents (however designated, whether voting or non-voting) of such
Person’s capital, whether now outstanding or issued after the Closing Date, including common
shares, ordinary shares, preferred shares, membership interests or share capital in a limited
liability company or other Person, limited or general partnership interests in a partnership,
beneficial interests in trusts or any other equivalent of such ownership interest or any options,
warrants and other rights to acquire such shares or interests, including rights to allocations and
distributions,

A-4

 

dividends, redemption payments and liquidation payments, but in any event excluding any membership
interest in the Issuer held by the Independent Member.

     “Change in Law” means the occurrence, after the date of the Memorandum, of any of the
following: (a) the adoption or taking effect of any law, rule, statute, ordinance, regulation or
treaty; (b) any change in any law, rule, statute, ordinance, regulation or treaty or in the
administration, interpretation or application thereof by any Governmental Authority whether or not
such change can be relied on as precedent; or (c) the making or issuance of any guideline,
directive, private ruling or administrative guidance (whether or not having the force of law) by
any Governmental Authority (including any IRS private letter ruling or field service advisory).

     “Change of Control” means, with respect to an Equityholder (or any parent entity of an
Equityholder), any merger, consolidation or amalgamation (or any transaction substantially similar
to any of the foregoing) with, or, in the case of clause (a) below, a sale of all or substantially
all of the assets of such Equityholder (or such parent entity) to, any other Person if such
Equityholder (or such parent entity) (a) is not the continuing or surviving entity but the
continuing or surviving entity shall have assumed all of the obligations of such Equityholder under
the Deal Documents to which such Equityholder is a party immediately prior to such transaction
(including such Equityholder’s obligations under the Pledge and Security Agreement in accordance
with Sections 6.1 and 17.1 of the Pledge and Security Agreement) or (b) is the continuing or
surviving entity.

     “Class A Notes” means the Original Class A Notes and any Refinancing Notes issued to
refinance the foregoing.

     “Clearstream” means Clearstream Banking, a French société anonyme.

     “Closing Date” means March 9, 2011.

     “Closing Day Accounts” has the meaning set forth in Section 3.1(b) of the Indenture.

     “Code” means the Internal Revenue Code of 1986, as amended, and the regulations
thereunder.

     “Collateral” has the meaning set forth in the Granting Clause of the Indenture.

     “Collection Account” has the meaning set forth in Section 3.1(a) of the Indenture.

     “Collections” means, without duplication, (a) the Royalties, (b) the Currency Hedge
Payments, (c) any net investment income on amounts on deposit in the Accounts (other than the
Capital Account) and (d) any other amounts received by the Issuer (other than the proceeds of any
Notes and capital contributions from the Equityholders), including any amounts payable to the
Issuer pursuant to Section 4.5(c) of the Purchase and Sale Agreement or Article VI of the Purchase
and Sale Agreement in respect of the Royalties.

     “Compound” has the meaning set forth in Section 1.1(m) of the Counterparty License
Agreement.

A-5

 

     “Confidential Information” means, as it relates to the Seller and its Affiliates, the
Licensed Products and the Intellectual Property Rights, all information (whether written or oral,
or in electronic or other form) furnished after the Closing Date involving or relating in any way,
directly or indirectly, to the Purchased Assets or the Royalties, including (a) any license,
sublicense, assignment, product development, royalty, sale, supply or other agreements (including
the Counterparty License Agreement, the UAB Agreement and the Currency Hedge Agreement) involving
or relating in any way, directly or indirectly, to the Purchased Assets, the Royalties or the
intellectual property, compounds or products giving rise to the Purchased Assets, and including all
terms and conditions thereof and the identities of the parties thereto, (b) any reports, data,
materials or other documents of any kind concerning or relating in any way, directly or indirectly,
to the Seller, the Purchased Assets, the Royalties or the intellectual property, compounds or
products giving rise to the Purchased Assets, and including reports, data, materials or other
documents of any kind delivered pursuant to or under any of the agreements referred to in clause
(a) above, and (c) any inventions, devices, improvements, formulations, discoveries, compositions,
ingredients, patents, patent applications, know-how, processes, trial results, research,
developments or any other intellectual property, trade secrets or information involving or relating
in any way, directly or indirectly, to the Purchased Assets or the compounds or products giving
rise to the Purchased Assets.

     “Confidentiality Agreement” means, with respect to Noteholders or Beneficial Holders
at the Closing Date with respect to the Original Class A Notes (or, with respect to Noteholders or
Beneficial Holders with respect to any Subordinated Notes or any Refinancing Notes), a
confidentiality agreement for the benefit of the Issuer provided to the Registrar on or prior to
the Closing Date (or on or prior to the date of issuance of any such Subordinated Notes or
Refinancing Notes), and otherwise means a confidentiality agreement for the benefit of the Issuer
substantially in the form of Exhibit B to the Indenture or substantially in the form of any
confidentiality agreement referenced in Schedule 1 to an applicable Purchase Agreement.

     “Confidential Parties” has the meaning set forth in Section 12.13 of the Indenture.

     “Corporate Trust Office” means the office of the Trustee in the city at which at any
particular time the Trustee’s duties under the Transaction Documents shall be principally
administered and, on the Closing Date, shall be U.S. Bank National Association, One Federal Street,
3rd Floor, Boston, Massachusetts 02110, Attention: Corporate Trust Services (JPR Royalty Sub LLC /
BioCryst).

     “Counterparty” means Shionogi & Co., Ltd., a Japanese corporation.

     “Counterparty Instruction” has the meaning set forth in Section 1.1 of the Purchase
and Sale Agreement.

     “Counterparty License Agreement” means that certain License, Development and
Commercialization Agreement dated as of February 28, 2007, as amended by that certain First
Amendment to License, Development and Commercialization Agreement dated as of September 30, 2008,
that certain letter agreement dated May 10, 2010 and that certain Consent Agreement dated as of
November 2, 2010, between the Seller and Counterparty.

A-6

 

     “Currency Hedge Agreement” means that certain Confirmation (including the related
letter agreement) dated as of March 9, 2011 and the ISDA Master Agreement (including the schedule
and credit support annex included therein) (solely insofar as such ISDA Master Agreement relates to
such Confirmation and not to any other “Transaction” as such term is defined in such ISDA Master
Agreement) dated as of March 7, 2011, in each case between the Seller and the Currency Hedge
Provider (and any replacement foreign currency hedge arrangement entered into by the Seller as
permitted by Section 4.11(e)(i) of the Purchase and Sale Agreement) and, with respect to such
letter agreement, among the Seller, the Currency Hedge Provider, the Issuer and the Trustee.

     “Currency Hedge Payments” means the amounts required to be paid to the Seller by the
Currency Hedge Provider pursuant to the Currency Hedge Agreement (subject to all of the Currency
Hedge Provider’s rights under the Currency Hedge Agreement (including, to the extent provided in
the Currency Hedge Agreement, liquidation, netting and setoff rights, specified conditions
precedent to the Currency Hedge Provider’s required payments and performance and rights to realize
on margin or other collateral)) except any amount required to be paid to the Seller by the Currency
Hedge Provider pursuant to the Currency Hedge Agreement as a result of a termination of the
Currency Hedge Agreement by the Seller permitted by Section 4.11(e) of the Purchase and Sale
Agreement.

     “Currency Hedge Provider” means Morgan Stanley Capital Services Inc.

     “Deal Documents” means the Transaction Documents, the Purchase and Sale Agreement, the
Bill of Sale and the Counterparty Instruction.

     “Default” means a condition, event or act that, with the giving of notice or the lapse
of time or both, would constitute an Event of Default.

     “Definitive Notes” has the meaning set forth in Section 2.1(b) of the Indenture.

     “Direction” has the meaning set forth in Section 1.3(c) of the Indenture.

     “Distribution Report” has the meaning set forth in Section 2.13(a) of the Indenture.

     “Dollar” or the sign “$” means United States dollars.

     “DTC” means The Depository Trust Company, its nominees and their respective
successors.

     “DTC List” has the meaning set forth in Section 2.5(d) of the Indenture.

     “Eligibility Requirements” has the meaning set forth in Section 2.3(c) of the
Indenture.

     “Eligible Account” means a trust account maintained on the books and records of an
Eligible Institution in the name of the Issuer.

     “Eligible Institution” means any bank organized under the laws of the U.S. or any
state thereof or the District of Columbia (or any domestic branch of a foreign bank), which at all
times

A-7

 

has either (a) a long-term unsecured debt rating of at least A2 by Moody’s and A by S&P or (b) a
certificate of deposit rating of at least P-1 by Moody’s and A-1 by S&P.

     “Eligible Investments” means, in each case, book-entry securities, negotiable
instruments or securities represented by instruments in bearer or registered form that evidence:

     (a) direct obligations of, and obligations fully Guaranteed as to timely payment of
principal and interest by, the U.S. or any agency or instrumentality thereof the obligations
of which are backed by the full faith and credit of the U.S. (having original maturities of
no more than 365 days or such lesser time as is required for the distribution of funds); or

     (b) demand deposits, time deposits or certificates of deposit of the Operating Bank
or of depositary institutions or trust companies organized under the laws of the U.S. or any
state thereof or the District of Columbia (or any domestic branch of a foreign bank) with
capital and surplus of not less than $500,000,000 (i) having original maturities of no more
than 365 days or such lesser time as is required for the distribution of funds;
provided, that, at the time of investment or contractual commitment to invest
therein, the short-term debt rating of such depositary institution or trust company shall be
at least P-1 by Moody’s and A-1 by S&P or (ii) having maturities of more than 365 days and,
at the time of the investment or contractual commitment to invest therein, a rating of at
least A2 by Moody’s and A by S&P;

provided, however, that no investment shall be made in any obligations of any
depositary institution or trust company that is identified in a written notice to the Trustee from
the Issuer or the Servicer as having a contractual right to set off and apply any deposits held, or
other indebtedness owing, by the Issuer to or for the credit or the account of such depositary
institution or trust company, unless such contractual right by its terms expressly excludes all
Eligible Investments.

     “Equityholder” means a holder of Capital Securities of the Issuer. The only
Equityholder as of the Closing Date is the Seller.

     “ERISA” means the U.S. Employee Retirement Income Security Act of 1974, as amended.

     “ERISA Affiliate” means any trade or business that is treated as a single employer
with the Issuer or the Seller under Section 414 of the Code.

     “Escrow Account” has the meaning set forth in Section 3.1(a) of the Indenture.

     “Escrow List” has the meaning set forth in Section 2.5(d) of the Indenture.

     “Euroclear” means Euroclear Bank S.A./N.V., as operator of the Euroclear system.

     “Event of Default” has the meaning set forth in Section 4.1 of the Indenture.

     “Excess Holder Event” has the meaning set forth in Section 2.17 of the Indenture.

A-8

 

     “Exchange Act” means the U.S. Securities Exchange Act of 1934, as amended.

     “Expenses” means any and all reasonable out-of-pocket fees, costs and expenses of the
Issuer, including the reasonable fees, expenses and indemnities of the Service Providers
(provided, that, with respect to the Servicer, such expenses shall only be the Servicing
Fee and reasonable out-of-pocket expenses), reasonable and customary directors and officers
liability insurance for any directors and officers of the Issuer, the fees and out-of-pocket
expenses of counsel to the Independent Member, the Trustee and the Issuer incurred after the
Closing Date in connection with the transactions contemplated by the Deal Documents, any Audit
Expenses, the fees and expenses of any nationally recognized independent public accounting firm
engaged as auditors of the Issuer (including any fees incurred by any accounting firm in connection
with auditing the records of Counterparty), any expenses incurred in connection with the exercise
of audit rights at the direction of the Issuer or at the direction of the Noteholders pursuant to
Section 6.14(a) of the Indenture and any payments by the Issuer to third parties in respect of
obligations for which indemnification payments have been received from the Seller;
provided, however, that, except as expressly provided in the Indenture, Expenses
shall not include any Transaction Expenses, any amounts related to any indemnification or
contribution obligations of the Issuer set forth in the Issuer Organizational Documents, any
Servicing Fee to the extent greater than $20,000 per year, any amounts payable on the Notes
pursuant to Section 3.7(a)(i), 3.7(a)(iii), 3.7(a)(iv) and 3.7(a)(v) of the Indenture, any fees,
costs or expenses relating to the Subordinated Notes or any other amounts ranking pari passu with
or junior to interest payable on the Class A Notes in the priority of payments set forth under
Section 3.7 of the Indenture.

     “Field” has the meaning set forth in Section 1.1(u) of the Counterparty License
Agreement.

     “Final Legal Maturity Date” means, with respect to (a) the Original Class A Notes,
December 1, 2020, and (b) with respect to any Subordinated Notes or Refinancing Notes, the date
specified in the indenture supplemental to the Indenture providing for their issuance;
provided, that the Final Legal Maturity Date with respect to any Subordinated Notes where
the proceeds thereof are not used to redeem or refinance all of the Outstanding Class A Notes shall
be no earlier than December 1, 2020.

     “Fixed Rate Notes” means (a) the Original Class A Notes and (b) any Subordinated Notes
or Refinancing Notes issued with a fixed rate of interest.

     “Floating Rate Notes” means any Subordinated Notes or Refinancing Notes issued with a
floating or variable rate of interest.

     “GAAP” means generally accepted accounting principles in effect in the United States
from time to time.

     “Global Notes” means any 144A Global Note and Regulation S Global Note.

     “Governmental Authority” means the government of the United States, any other nation
or any political subdivision thereof, whether state or local, and any agency, authority (including
supranational authority), commission, instrumentality, regulatory body, court, central bank or

A-9

 

other Person exercising executive, legislative, judicial, taxing, regulatory or administrative
powers or functions of or pertaining to government.

     “Guarantee” means any obligation, contingent or otherwise, of any Person directly or
indirectly guaranteeing any Indebtedness or other obligation of any other Person and, without
limiting the generality of the foregoing, any obligation, direct or indirect, contingent or
otherwise, of such Person (a) to purchase or pay (or advance or supply funds for the purchase or
payment of) such Indebtedness or other obligation of such other Person or (b) entered into for
purposes of assuring in any other manner the obligee of such Indebtedness or other obligation of
the payment thereof or to protect such obligee against loss in respect thereof (in whole or in
part); provided, that the term “Guarantee” shall not include endorsements for
collection or deposit in the ordinary course of business. The term “Guarantee” when used
as a verb has a corresponding meaning.

     “Holder Lists” has the meaning set forth in Section 2.17 of the Indenture.

     “Incur” has the meaning set forth in Section 5.2(d) of the Indenture.

     “Indebtedness” means, with respect to any Person at any date of determination (without
duplication), (a) all indebtedness of such Person for borrowed money or other similar monetary
obligations, (b) all obligations of such Person evidenced by bonds, debentures, notes or other
similar instruments, (c) all obligations of such Person as an account party in respect of letters
of credit or other similar instruments (including reimbursement obligations with respect thereto),
(d) all the obligations of such Person to pay the deferred and unpaid purchase price of property or
services (other than obligations to trade creditors incurred in the ordinary course of business in
connection with the obtaining of goods, materials or services), which purchase price is due more
than 90 days after the date of purchasing such property or service or taking delivery and title
thereto or the completion of such services, and payment deferrals arranged primarily as a method of
raising funds to acquire such property or service, (e) all monetary obligations of such Person and
its Subsidiaries under any leasing or similar arrangement that have been (or, in accordance with
GAAP, should be) classified as capitalized leases, (f) all Guarantees of such Person in respect of
any of the foregoing, (g) all monetary obligations of such Person with respect to any interest rate
hedge, cap, floor, swap, option or other interest rate hedge agreement, (h) all Indebtedness (as
defined in clauses (a) through (g) of this definition) of other Persons secured by a lien on any
asset of such Person, whether or not such Indebtedness is assumed by such Person, and (i) all
Indebtedness (as defined in clauses (a) through (g) of this definition) of other Persons Guaranteed
by such Person. Notwithstanding the foregoing, “Indebtedness” shall not include any surety
or performance bonds required to be obtained in connection with the performance or enforcement by
the Issuer of any Deal Document or the Counterparty License Agreement or the Issuer’s defense of
any action, suit or proceeding.

     “Indemnitee” has the meaning set forth in Section 19.1 of the Pledge and Security
Agreement.

     “Indemnitees” has the meaning set forth in Section 19.1 of the Pledge and Security
Agreement.

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     “Indenture” means that certain indenture, dated as of the Closing
Date, by and between the Issuer and the Trustee.

     “Indenture Estate” has the meaning set forth in the Granting Clause of the Indenture.

     “Independent Member” means a Member (i) who is not at the time of such Person’s
admission to the Issuer, (ii) who is not and (iii) who has not been at any time during the
preceding five years: (a) a director, manager, officer or employee of the Issuer or an Equityholder
(other than in the capacity of Independent Member) or any Affiliate of the Issuer or an
Equityholder (other than in the capacity of Independent Member); (b) a Person related to any
officer, director, manager or employee of the Issuer or an Equityholder (other than in the capacity
of Independent Member) or any Affiliate of the Issuer or an Equityholder (other than in the
capacity of Independent Member); (c) a holder (directly or indirectly) of any Voting Securities of
the Issuer or an Equityholder or any Affiliate of the Issuer or an Equityholder (other than in the
capacity of Independent Member); (d) a Person related to a holder (directly or indirectly) of any
Voting Securities of the Issuer or an Equityholder or any Affiliate of the Issuer or an
Equityholder (other than in the capacity of Independent Member); (e) a creditor, supplier,
contractor, purchaser, customer or any other Person who derives any of his, her or its revenues
from interactions with the Issuer or an Equityholder or any Affiliate of the Issuer or an
Equityholder or a family member of such creditor, supplier, contractor, purchaser, customer or
other Person; (f) a trustee in bankruptcy or other insolvency proceeding for, or a reorganization
of, an Equityholder or any Affiliate of an Equityholder; or (g) a Person who controls (directly or
indirectly) the Issuer or an Equityholder or any Affiliate of the Issuer or an Equityholder or any
creditor, supplier, employee, officer, director, manager or contractor of the Issuer or an
Equityholder or any Affiliate of the Issuer or an Equityholder.

     “Initial Interest Reserve Amount” means $3,000,000.

     “Institutional Accredited Investor” means a Person that is an accredited investor as
that term is defined in Rule 501(a)(1), (2), (3) or (7) under the Securities Act.

     “Intellectual Property Rights” has the meaning set forth in Section 1.1 of the
Purchase and Sale Agreement.

     “Interest Accrual Period” means the period beginning on (and including) the Closing
Date (or, with respect to any Subordinated Notes or any Refinancing Notes, the date of issuance of
such Subordinated Notes or Refinancing Notes) and ending on (and including) September 1, 2011 and
each successive period beginning on (and including) September 2 of each year and ending on (and
including) September 1 of the succeeding year; provided, however, that the final
Interest Accrual Period shall end on but exclude the final Payment Date (or, if earlier, with
respect to any class of Notes repaid in full, the date such class of Notes is repaid in full).

     “Interest Amount” means, with respect to the Outstanding Principal Balance of any
class of Notes, on any Payment Date, the amount of accrued and unpaid interest at the Stated Rate
of Interest with respect to the Outstanding Principal Balance of such class of Notes on such
Payment Date (including any Additional Interest, if any), determined in accordance with the

A-11

 

terms thereof (including interest accruing after the commencement of a proceeding in bankruptcy,
insolvency or similar law, whether or not permitted as a claim under such law).

     “Interest Reserve Account” has the meaning set forth in Section 3.1(a) of the
Indenture.

     “Interest Shortfall” has the meaning set forth in Section 3.5(a)(x) of the Indenture.

     “Involuntary Bankruptcy” means, without the consent or acquiescence of the Issuer, the
entering of an order for relief or approving a petition for relief or reorganization or any other
petition seeking any reorganization, arrangement, composition, readjustment, liquidation,
dissolution or other similar relief under any present or future bankruptcy, insolvency or similar
statute, law or regulation, or the filing of any such petition against the Issuer, or, without the
consent or acquiescence of the Issuer, the entering of an order appointing a trustee, custodian,
receiver or liquidator of the Issuer or of all or any substantial part of the property of the
Issuer, in each case where such petition or order shall remain unstayed or shall not have been
stayed or dismissed within 90 days from entry thereof.

     “IRS” means the U.S. Internal Revenue Service.

     “Issuer” means JPR Royalty Sub LLC, a Delaware limited liability company, as issuer of
the Notes pursuant to the Indenture.

     “Issuer Organizational Documents” means the certificate of formation of the Issuer
dated January 14, 2011 and effective January 20, 2011 and the limited liability company agreement
of the Issuer dated as of the Closing Date.

     “Issuer Pledged Collateral” has the meaning set forth in Section 2.1 of the Pledge and
Security Agreement.

     “Issuer Pledged Equity” has the meaning set forth in Section 2.1(a) of the Pledge and
Security Agreement.

     “Judgment Currency” has the meaning set forth in Section 12.9(e) of the Indenture.

     “Legend” has the meaning set forth in Section 2.2 of the Indenture.

     “Licensed Product” has the meaning set forth in Section 1.1(jj) of the Counterparty
License Agreement.

     “Lien” means any security interest, mortgage, pledge, hypothecation, assignment,
deposit arrangement, encumbrance, lien (statutory or otherwise), charge against or interest in
property or other priority or preferential arrangement of any kind or nature whatsoever, including
any conditional sale, any sale with recourse or any agreement to give any security interest.

     “Loss” means any loss, set-off, off-set, rescission, counterclaim, reduction,
deduction, defense, cost, charge, expense, interest, fee, payment, demand, liability, claim,
action, proceeding, penalty, fine, damages, judgment, order or other sanction.

A-12

 

     “Manager” means the manager of the Issuer.

     “Material Adverse Change” means any event, circumstance or change resulting in a
material adverse effect on (a) the legality, validity or enforceability of any of the Deal
Documents, the Counterparty License Agreement or the back-up security interest granted pursuant to
Section 2.1(d) of the Purchase and Sale Agreement, (b) the right or ability of the Seller (or any
permitted assignee), the Issuer or the Servicer, as the case may be, to perform its obligations
under any of the Deal Documents or the Counterparty License Agreement, in each case to which it is
a party, or to consummate the transactions contemplated under any of the Transaction Documents or
the Counterparty License Agreement, (c) the rights or remedies of the Issuer under any of the Deal
Documents or the Counterparty License Agreement, (d) the timing, amount or duration of the
Royalties or any Currency Hedge Payments, (e) the Purchased Assets, (f) the Intellectual Property
Rights or (g) the ability of the Trustee to realize the practical benefit of the Pledge and
Security Agreement (including any failure to have a perfected Lien on any of the Issuer Pledged
Collateral as required by the Indenture).

     “Member” means a member of the Issuer.

     “Memorandum” means the private placement memorandum of the Issuer for the Original
Class A Notes dated March 1, 2011.

     “Moody’s” means Moody’s Investors Service, Inc. and any successor thereto or, if such
corporation or its successor shall for any reason no longer perform the functions of a rating
agency, “Moody’s” shall be deemed to refer to any other nationally recognized statistical
rating organization (within the meaning ascribed thereto by the Exchange Act) designated by the
Issuer.

     “Non-U.S. Person” means a person who is not a U.S. person within the meaning of
Regulation S.

     “Noteholder” means any Person in whose name a Note is registered from time to time in
the Register for such Note.

     “Note Purchase Price” has the meaning set forth in Section 3.1 of the Purchase
Agreements.

     “Note Purchasers” has the meaning set forth in Section 1.1 of the Purchase Agreements.

     “Notes” means the Original Class A Notes, any Subordinated Notes and any Refinancing
Notes.

     “Notices” means notices, demands, certificates, requests, directions, instructions and
communications.

     “Officer’s Certificate” means a certificate signed by, with respect to the Issuer, a
Responsible Officer of the Issuer and, with respect to any other Person, any officer, director,
manager, partner, trustee or equivalent representative of such Person.

A-13

 

     “Operating Bank” means U.S. Bank National Association or any other Eligible
Institution at which the Accounts are held; provided, that (a) upon the resignation or
removal and the replacement of the Trustee pursuant to the terms of the Indenture, the successor
trustee appointed thereunder shall be the Operating Bank, and (b) if at any time the Operating Bank
ceases to be an Eligible Institution, a successor shall be appointed by the Issuer (or the
Servicer) on behalf of the Trustee and all Accounts shall thereafter be transferred to and be
maintained at such successor in the name of the Trustee and such successor shall thereafter be the
“Operating Bank”.

     “Opinion of Counsel” means a written opinion signed by legal counsel, who may be an
employee of or counsel to the Issuer or the Seller, that meets the requirements of Section 1.2 of
the Indenture.

     “Option” means a foreign currency exchange option set forth in the Currency Hedge
Agreement.

     “Options” means, collectively, the foreign currency exchange options set forth in the
Currency Hedge Agreement.

     “Optional Redemption” has the meaning set forth in Section 3.9(b) of the Indenture.

     “Original Class A Notes” means the JPR PhaRMASM Senior Secured 14% Notes
due 2020 of the Issuer in the initial Outstanding Principal Balance of $30,000,000, substantially
in the form of Exhibit A to the Indenture.

     “Other Agreements” has the meaning set forth in Section 3.1 of the Purchase
Agreements.

     “Other Note Purchasers” has the meaning set forth in Section 3.1 of the Purchase
Agreements.

     “Other Prices” has the meaning set forth in Section 3.1 of the Purchase Agreements.

     “Outstanding” means (a) with respect to the Notes of any class at any time, all Notes
of such class theretofore authenticated and delivered by the Trustee except (i) any such Notes
cancelled by, or delivered for cancellation to, the Trustee, (ii) any such Notes, or portions
thereof, for the payment of principal of and accrued and unpaid interest on which moneys have been
distributed to Noteholders by the Trustee and any such Notes, or portions thereof, for the payment
or redemption of which moneys in the necessary amount have been deposited in the Redemption Account
for such Notes; provided, that, if such Notes are to be redeemed prior to the maturity
thereof in accordance with the requirements of Section 3.9 of the Indenture, written notice of such
Redemption shall have been given and not rescinded as provided in Section 3.10 of the Indenture, or
provision satisfactory to the Trustee shall have been made for giving such written notice, and, if
Redemption does not occur, then this clause (ii) ceases to apply as of the Payment Date that was
supposed to be the date of Redemption, and (iii) any such Notes in exchange or substitution for
which other Notes, as the case may be, have been authenticated and delivered, or which have been
paid pursuant to the terms of the Indenture (unless proof satisfactory to the Trustee is presented
that any of such Notes is held by a Person in whose hands such Note is a legal, valid and binding
obligation of the Issuer), and (b) when used with respect

A-14

 

to any other evidence of Indebtedness, at any time, any principal amount thereof then unpaid and
outstanding (whether or not due or payable).

     “Outstanding Principal Balance” means, with respect to any Note or other evidence of
Indebtedness Outstanding, the total principal amount of such Note or other evidence of Indebtedness
unpaid and Outstanding at any time, as determined in the case of the Notes in the Calculation
Report to be provided to the Issuer (or the Servicer) and the Trustee by the Calculation Agent
pursuant to Section 3.5 of the Indenture.

     “Paying Agent” has the meaning set forth in Section 2.3(a) of the Indenture.

     “Payment Date” means each September 1, commencing on September 1, 2011, and the Final
Legal Maturity Date; provided, that, if any such date would otherwise fall on a day that is
not a Business Day, the Payment Date falling on such date shall be the first following day that is
a Business Day; provided, further, however, that, if any such date on or
after September 1, 2016 would otherwise fall on a day that is not a Business Day, the Payment Date
falling on such date shall be the first preceding day that is a Business Day (in which case the
full interest payment for the related Interest Accrual Period shall nonetheless be payable on such
first preceding Business Day).

     “Permanent Regulation S Global Note” has the meaning set forth in Section 2.1(b) of
the Indenture.

     “Permitted Holder” means (a) the Seller, (b) the Issuer and (c) any Person (including
the Noteholders) that has executed a Confidentiality Agreement and delivered such Confidentiality
Agreement to the Registrar in accordance with the terms of the Indenture.

     “Permitted Lien” means (a) any lien for Taxes, assessments and governmental charges or
levies not yet due and payable or that are being diligently contested in good faith by appropriate
proceedings and for which adequate reserves in accordance with GAAP have been set aside on the
books of the relevant Person, (b) any Lien created in favor of the Trustee and (c) any other Lien
expressly permitted under the Deal Documents (including any security interest created or required
to be created under the Indenture, including in connection with the issuance of any Subordinated
Notes and any Refinancing Notes).

     “Person” means any natural person, firm, corporation, limited liability company,
partnership, joint venture, association, joint-stock company, trust, unincorporated organization,
Governmental Authority or any other legal entity, including public bodies, whether acting in an
individual, fiduciary or other capacity.

     “Placement Agent” means Morgan Stanley & Co. Incorporated.

     “Plan” means, with respect to any Person, any employee benefit plan (within the
meaning of Section 3(3) of ERISA), whether or not subject to ERISA, in each case that is (or within
the preceding six years has been) maintained, or to which contributions are (or within the
preceding six years have been) required to be made by such Person or an ERISA Affiliate or with
respect to which such Person may have any liability.

A-15

 

     “Plan Assets” has the meaning given to such term by Section 3(42) of ERISA and
regulations issued by the U.S. Department of Labor, but also includes assets of an employee benefit
plan (within the meaning of Section 3(3) of ERISA) subject to Similar Laws.

     “Pledge and Security Agreement” means that certain pledge and security agreement dated
as of the Closing Date made by the Equityholders to the Trustee.

     “Premium” means, with respect to any Note on any Redemption Date, any Redemption
Premium, if applicable, or, with respect to any Redemption Date, the portion of the Redemption
Price of the Notes being redeemed in excess of the Outstanding Principal Balance of the Notes being
redeemed.

     “Price” has the meaning set forth in Section 3.1 of the Purchase Agreements.

     “Purchase Agreement” means that certain note purchase agreement dated the Closing Date
among the Issuer, the Seller and the Purchaser party thereto.

     “Purchase Agreements” means, collectively, each Purchase Agreement and the Other
Agreements.

     “Purchase and Sale Agreement” means that certain purchase and sale agreement dated as
of the Closing Date between the Seller and the Issuer.

     “Purchased Assets” has the meaning set forth in Section 1.1 of the Purchase and Sale
Agreement.

     “Purchase Price” has the meaning set forth in Section 2.3 of the Purchase and Sale
Agreement.

     “Purchaser” has the meaning set forth in Section 1.1 of the Purchase Agreements.

     “Purchaser Indemnified Party” has the meaning set forth in Section 6.1 of the Purchase
and Sale Agreement.

     “QIB” means a qualified institutional buyer within the meaning of Rule 144A.

     “RAPIACTA” means (i) the brand name for peramivir in Japan and (ii) the equivalent
product sold by Counterparty or its Affiliates in Taiwan under such brand name or another brand
name.

     “Receiver” means any Person or Persons appointed as (and any additional Person or
Persons appointed or substituted as) administrative receiver, receiver, manager or receiver and
manager.

     “Record Date” means, with respect to each Payment Date, the close of business on the
fifteenth day preceding such Payment Date and, with respect to the date on which any Direction is
to be given by the Noteholders, the close of business on the last Business Day prior to the
solicitation of such Direction.

A-16

 

     “Redemption” means any Optional Redemption and any other redemption of Notes described
in Section 3.9(c) of the Indenture.

     “Redemption Account” has the meaning set forth in Section 3.1(a) of the Indenture.

     “Redemption Date” means the date, which may be any Business Day on or after March 9,
2012, on which Notes are redeemed pursuant to a Redemption.

     “Redemption Premium” means, in the case of any Subordinated Notes or Refinancing
Notes, the amount, if any, specified in the Resolution and set forth in any indenture supplemental
to the Indenture to be paid in the event of a Redemption of such Subordinated Notes or Refinancing
Notes separately from the Redemption Price.

     “Redemption Price” means (a) in respect of an Optional Redemption of the Original
Class A Notes, an amount equal to the product of (x) the applicable Class A Redemption Percentage
as set forth below and (y) the Outstanding Principal Balance of the Original Class A Notes that are
being redeemed on such Business Day, plus the accrued and unpaid interest to the Redemption Date on
the Original Class A Notes that are being redeemed:

	 	 	 
	Business Day	 	Class A Redemption Percentage
	From and including March 9, 2012
to and including March 8, 2013
	 	107.00%
	From and including March 9, 2013
to and including March 8, 2014
	 	103.50%
	From and including March 9, 2014 and thereafter
	 	100.00%

and (b) in respect of any Subordinated Notes or Refinancing Notes, the redemption price, if any,
plus the accrued and unpaid interest to the Redemption Date on the Subordinated Notes or
Refinancing Notes, as the case may be, established by or pursuant to a Resolution and set forth in
any indenture supplemental to the Indenture providing for the issuance of such Notes or designated
as such in the form of such Notes (any such Redemption Price in respect of any Subordinated Notes
or Refinancing Notes may include a Redemption Premium, and such Resolution and indenture
supplemental to the Indenture may specify a separate Redemption Premium).

     “Reference Date” means, with respect to each Interest Accrual Period, the day that is
two Business Days prior to the Payment Date on which such Interest Accrual Period commences;
provided, however, that the Reference Date with respect to the initial Interest
Accrual Period means the date that is two Business Days prior to the Closing Date (or, with respect
to any Subordinated Notes or any Refinancing Notes, the date that is two Business Days prior to the
date of issuance of such Subordinated Notes or Refinancing Notes).

     “Refinancing” has the meaning set forth in Section 2.15(a) of the Indenture.

     “Refinancing Expenses” means all Transaction Expenses incurred in connection with an
offering and issuance of Refinancing Notes.

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     “Refinancing Notes” means any class (or sub-class) of Notes issued by the Issuer under
the Indenture at any time and from time to time after the Closing Date pursuant to Section 2.15 of
the Indenture, the proceeds of which are used to repay all of the Outstanding Principal Balance of
a class of Notes.

     “Register” has the meaning set forth in Section 2.3(a) of the Indenture.

     “Registrar” has the meaning set forth in Section 2.3(a) of the Indenture.

     “Regulation S” means Regulation S under the Securities Act.

     “Regulation S Global Note Exchange Date” means the date of exchange of any Temporary
Regulation S Global Note for any Permanent Regulation S Global Note, which date shall be 40 days
after the Closing Date (or, with respect to any Subordinated Notes or any Refinancing Notes, 40
days after the date of issuance of such Subordinated Notes or Refinancing Notes).

     “Regulation S Global Notes” has the meaning set forth in Section 2.1(b) of the
Indenture.

     “Relevant Calculation Date” has the meaning set forth in Section 3.5(a) of the
Indenture.

     “Relevant Information” means any information provided to the Trustee, the Calculation
Agent or the Paying Agent in writing by any Service Provider retained from time to time by the
Issuer pursuant to the Deal Documents.

     “Resolution” means a copy of a resolution certified by a Responsible Officer of the
Issuer as having been duly adopted by the Issuer and being in full force and effect on the date of
such certification.

     “Responsible Officer” means (a) with respect to the Trustee, any officer within the
Corporate Trust Office, including any principal, vice president, managing director, director,
manager, associate or other officer of the Trustee customarily performing functions similar to
those performed by any of the above-designated officers and also, with respect to a particular
matter, any other officer to whom such matter is referred because of such officer’s knowledge and
familiarity with the particular subject, (b) with respect to the Seller, any officer of the Seller,
and (c) with respect to the Issuer, any officer of the Manager or person designated by the
governing body of the Manager as a Responsible Officer for purposes of the Deal Documents.

     “Royalties” has the meaning set forth in Section 1.1 of the Purchase and Sale
Agreement.

     “Rule 144A” means Rule 144A under the Securities Act.

     “S&P” means Standard & Poor’s Ratings Services, a division of The McGraw-Hill
Companies, Inc., and any successor thereto or, if such division or its successor shall for any
reason no longer perform the functions of a rating agency, “S&P” shall be deemed to refer
to any other nationally recognized statistical rating organization (within the meaning ascribed
thereto by the Exchange Act) designated by the Issuer.

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     “SEC” means the U.S. Securities and Exchange Commission.

     “Secured Obligations” has the meaning set forth in the Granting Clause of the
Indenture.

     “Securities Act” means the U.S. Securities Act of 1933, as amended.

     “Security Interest” means the security interest granted or expressed to be granted in
the Collateral pursuant to the Granting Clause of the Indenture and in the Issuer Pledged
Collateral pursuant to the Pledge and Security Agreement.

     “Seller” means BioCryst Pharmaceuticals, Inc., a Delaware corporation.

     “Seller Payments” has the meaning set forth in Section 3.4 of the Indenture.

     “Seller Shortfall” means the amount, if any, payable by the Seller to Counterparty
under the Counterparty License Agreement or to the Currency Hedge Provider under the Currency Hedge
Agreement that is due and payable but that has not been paid by the Seller.

     “Seller Shortfall Payment” means any payment made by the Trustee in respect of any
Seller Shortfall.

     “Senior Claim” has the meaning set forth in Section 10.1(a) of the Indenture.

     “Senior Class of Notes” means (a) so long as any Class A Notes are Outstanding, the
Class A Notes, or (b) if no Class A Notes are Outstanding, the class or classes (or sub-class or
sub-classes) of Subordinated Notes defined as such pursuant to the Resolution(s) and/or
indenture(s) supplemental to the Indenture providing for the issuance of such Subordinated Notes.

     “Senior Trustee” means the Trustee, acting in its capacity as the trustee of the
Senior Class of Notes.

     “Service Providers” means the Servicer, the Trustee, the Independent Member, the
Calculation Agent, the Paying Agent, the Registrar, the Operating Bank, any outside law firm or
accounting firm providing services to the Issuer and any Person that becomes a Servicer, the
Trustee, the Independent Member, the Calculation Agent, the Paying Agent, the Registrar or the
Operating Bank in accordance with the terms of the applicable agreement and, subject to the written
approval of the Noteholders of a majority of the Outstanding Principal Balance of the Senior Class
of Notes, any other Person designated as a Service Provider by the Issuer.

     “Servicer” means the Seller, acting in its capacity as servicer pursuant to the
Servicing Agreement (or any other Person appointed to succeed the Seller as such or any successor
thereto pursuant to the Servicing Agreement).

     “Servicer Termination Event” means any one of the following events:

     (a) the Seller shall resign as Servicer in accordance with the terms of the
Servicing Agreement;

A-19

 

     (b) the Servicer shall fail to pay any amount when due under the Servicing
Agreement and such failure shall continue unremedied for five Business Days;

     (c) the Servicer shall fail to deliver the Distribution Report and the other
required accompanying materials with respect to any Payment Date in accordance with the
provisions of the Servicing Agreement within five Business Days of the date such
Distribution Report and the other required accompanying materials are required to be
delivered under the Servicing Agreement; provided, however, that the
Servicer shall have received in a timely manner any Calculation Report (unless the failure
to receive such Calculation Report was due to the breach by the Servicer of Section
3.1(c)(vi) of the Servicing Agreement);

     (d) the Servicer shall fail to carry out its obligations under Section 3.1(c)(ii)
of the Servicing Agreement that shall have or reasonably be expected to have a material
adverse effect on the Noteholders;

     (e) the Servicer shall fail to carry out its obligations under Section 3.1(c)(v),
Section 3.1(c)(viii) or Section 3.1(c)(ix) of the Servicing Agreement;

     (f) the Servicer shall fail to observe or perform in any material respect any of
the covenants or agreements on the part of the Servicer contained in the Servicing Agreement
(other than for which provision is made in clauses (a) through (e) above) and such failure
shall continue unremedied for a period of 30 days after the date on which written notice of
such failure requiring the same to be remedied shall have been given to the Servicer by the
Trustee, and such failure continues to materially adversely affect the Noteholders for such
period;

     (g) a court having jurisdiction in the premises enters a decree or order for (i)
relief in respect of the Servicer under any Applicable Law relating to bankruptcy,
insolvency, receivership, winding-up, liquidation, reorganization, examination, relief of
debtors or other similar law in effect now or after the Closing Date, (ii) appointment of a
receiver, liquidator, examiner, assignee, custodian, trustee, sequestrator or similar
official of the Servicer or (iii) the winding-up or liquidation of the affairs of the
Servicer and, in each case, such decree or order shall remain unstayed or such writ or other
process shall not have been stayed or dismissed within 90 days from entry thereof;

     (h) the Servicer (i) commences a voluntary case under any Applicable Law relating
to bankruptcy, insolvency, receivership, winding-up, liquidation, reorganization,
examination, relief of debtors or other similar law in effect now or after the Closing Date,
or consents to the entry of an order for relief in any involuntary case under any such law,
(ii) consents to the appointment of or taking possession by a receiver, liquidator,
examiner, assignee, custodian, trustee, sequestrator or similar official of the Servicer or
for all or substantially all of the property and assets of the Servicer or (iii) effects any
general assignment for the benefit of creditors;

     (i) the Servicer’s business activities are terminated by any Governmental
Authority;

A-20

 

     (j) a material adverse change occurs in the financial condition or operations of
the Servicer that is a Material Adverse Change;

     (k) an Event of Default shall have occurred, other than an Event of Default solely
caused by the Trustee, the Calculation Agent, the Paying Agent or the Registrar failing to
perform any of its respective obligations under the Indenture or any other Transaction
Document; or

     (l) so long as the Seller is the Servicer, the Seller sells, transfers, conveys,
assigns, contributes or grants a majority of the Capital Securities of the Issuer to another
Person or Persons.

     “Servicing Agreement” means that certain servicing agreement dated as of the Closing
Date between the Issuer and the Seller.

     “Servicing Fee” has the meaning set forth in Section 2.1 of the Servicing Agreement.

     “Similar Laws” means, with respect to a Plan that is not subject to Section 406 of
ERISA or Section 4975 of the Code, all Applicable Laws that may affect the Plan’s investment in the
Notes and that is substantially similar to Section 406 of ERISA or Section 4975 of the Code.

     “Stated Rate of Interest” means, with respect to any class of the Notes for any
Interest Accrual Period, the interest rate set forth in such class of Notes for such Interest
Accrual Period.

     “Subordinated Claim” has the meaning set forth in Section 10.1(a) of the Indenture.

     “Subordinated Note Issuance” has the meaning set forth in Section 2.16(a) of the
Indenture.

     “Subordinated Notes” means any class (or sub-class) of Notes issued in such form as
shall be authorized by a Resolution and set forth in any indenture supplemental to the Indenture in
respect thereof pursuant to Section 2.16 of the Indenture and any Refinancing Notes issued to
refinance the foregoing.

     “Subsidiary” means, with respect to any Person, any other Person of which more than
50% of the outstanding Voting Securities of such other Person (irrespective of whether at the time
Capital Securities of any other class or classes of such other Person shall or might have voting
power upon the occurrence of any contingency) is at the time directly or indirectly owned or
controlled by such Person, by such Person and one or more other Subsidiaries of such Person or by
one or more other Subsidiaries of such Person.

     “Taxes” means (a) any and all taxes, fees, levies, duties, tariffs, imposts and other
charges of any kind (together with any and all interest, penalties, loss, damage, liability,
expense, additions to tax and additional amounts or costs incurred or imposed with respect thereto)
now or hereafter imposed, levied, collected, withheld or otherwise assessed by the U.S. or by any
state, local, foreign or other Governmental Authority (or any subdivision or agency thereof) or
other taxing authority, including taxes or other charges on or with respect to income, franchise,
windfall or other profits, gross receipts, property, sales, use, capital stock, payroll,
employment,

A-21

 

social security, workers’ compensation, unemployment compensation or net worth and similar charges
and taxes or other charges in the nature of excise, deduction, withholding, ad valorem, stamp,
transfer, value added, taxes on goods and services, escheat, gains taxes, license, registration and
documentation fees, customs duties, tariffs and similar charges, (b) liability for such a tax that
is imposed by reason of United States Treasury Regulation Section 1.1502-6 or similar provision of
law and (c) liability for the payment of any amounts as a result of any express or implied
obligation to indemnify any other Person with respect to the payment of any amounts described in
clause (a) or clause (b).

     “Temporary Regulation S Global Note” has the meaning set forth in Section 2.1(b) of
the Indenture.

     “Territory” means Japan and Taiwan.

     “Transaction Documents” means the Indenture, the Notes, the Servicing Agreement, the
Pledge and Security Agreement, the Purchase Agreements and the Currency Hedge Agreement, and each
other agreement pursuant to which the Trustee (or its agent) is granted a Lien to secure the
obligations under the Indenture or the Notes.

     “Transaction Expenses” means the out-of-pocket expenses payable by the Issuer in
connection with (a) the issuance of the Original Class A Notes, including placement fees, any
initial fees payable to Service Providers and the documented fees and expenses of Pillsbury
Winthrop Shaw Pittman LLP, counsel to the Noteholders in connection with the offering and issuance
of the Original Class A Notes, as set forth in the Purchase Agreements, and (b) the offering and
issuance of any Subordinated Notes or any Refinancing Notes, to the extent specified in the
Resolution authorizing such offering and issuance.

     “Trustee” means U.S. Bank National Association, a national banking association, as
initial trustee of the Notes under the Indenture, and any successor appointed in accordance with
the terms of the Indenture; provided, that, for purposes of Section 3.1(b) of the
Indenture, “Trustee” means U.S. Bank National Association, a national banking association,
as the Operating Bank and/or initial trustee of the Notes under the Indenture, as the context may
require.

     “Trustee Closing Account” means the account of the Issuer maintained with the Trustee
at U.S. Bank National Association, ABA No. 091000022, Account No. 173103321092, Ref. JPR Royalty,
Attention: Josh Tripi.

     “Trust Indenture Act” means the U.S. Trust Indenture Act of 1939, as amended.

     “UAB” means The UAB Research Foundation, a non-profit corporation.

     “UAB Agreement” means that certain Joint Research and License Agreement dated as of
November 23, 1994 between the Seller and UAB, as amended by that certain letter agreement dated
October 9, 1996 and by that certain Agreement dated as of December 16, 2010 between the Seller and
UAB.

A-22

 

     “UCC” means the Uniform Commercial Code as in effect from time to time in the State of
New York; provided, that, if, with respect to any financing statement or by reason of any
provisions of law, the perfection or the effect of perfection or non-perfection of the Liens
granted to the Trustee pursuant to the applicable Transaction Document is governed by the Uniform
Commercial Code as in effect in a jurisdiction of the United States other than the State of New
York, then “UCC” means the Uniform Commercial Code as in effect from time to time in such
other jurisdiction for purposes of the provisions of each Transaction Document and any financing
statement relating to such perfection or effect of perfection or non-perfection.

     “United States Treasury” means the U.S. Department of the Treasury.

     “U.S.” or “United States” means the United States of America, its 50 states,
each territory thereof and the District of Columbia.

     “U.S. Person” means a U.S. person within the meaning of Regulation S.

     “Voluntary Bankruptcy” means (a) an admission in writing by the Issuer of its
inability to pay its debts generally or a general assignment by the Issuer for the benefit of
creditors, (b) the filing of any petition or answer by the Issuer seeking to adjudicate itself as
bankrupt or insolvent, or seeking for itself any liquidation, winding-up, reorganization,
arrangement, adjustment, protection, relief or composition of the Issuer or its debts under any law
relating to bankruptcy, insolvency, receivership, winding-up, liquidation, reorganization,
examination, relief of debtors or other similar law now or hereafter in effect, or seeking,
consenting to or acquiescing in the entry of an order for relief in any case under any such law, or
the appointment of or taking possession by a receiver, trustee, custodian, liquidator, examiner,
assignee, sequestrator or other similar official for the Issuer or for any substantial part of its
property, or (c) limited liability company action taken by the Issuer to authorize any of the
actions set forth in clause (a) or clause (b) above.

     “Voting Securities” means, with respect to any Person, Capital Securities of any class
or kind ordinarily having the power to vote for the election of directors, managers or other voting
members of the governing body of such Person.

     “Yen” or the sign “¥” means Japanese yen.

A-23

 

EXHIBIT A

FORM OF ORIGINAL CLASS A NOTE

[INSERT THE APPLICABLE LEGEND(S) SET FORTH IN SECTION 2.2]

JPR ROYALTY SUB LLC

JPR PhaRMASM Senior Secured 14% Notes due 2020

Class A

			
	 	 	 
	No. __________
	 	CUSIP: __________

U.S.$__________

     JPR ROYALTY SUB LLC, a limited liability company organized under the laws of the State of
Delaware (herein referred to as the “Issuer”), for value received, hereby promises to pay
to CEDE & CO., or registered assigns, the principal amount set forth on Schedule I hereto
on or before December 1, 2020 (the “Final Legal Maturity Date”) and to pay interest
annually on the Outstanding Principal Balance hereof at a rate per annum equal to 14% (the
“Stated Rate of Interest”), from the date hereof until the Outstanding Principal Balance
hereof is paid or duly provided for, which interest shall be due and payable on each Payment Date;
provided, that, with respect to any Payment Date (other than the Final Legal Maturity Date
or any Redemption Date), any such interest in excess of the portion of the Available Collections
Amount available to pay such interest on such Payment Date and funds in the Interest Reserve
Account and the Capital Account (and available for interest payments pursuant to Section 3.8 of the
Indenture (as defined below)) shall be payable in full not later than the immediately succeeding
Payment Date (together with Additional Interest on the amount of unpaid interest from the Payment
Date on which it was due until the date on which it is paid, compounded annually on each Payment
Date). Interest on this Note in each Interest Accrual Period shall be calculated on the basis of a
360-day year consisting of twelve 30-day months on the Outstanding Principal Balance of this Note.
If this Note is issued in the form of a Global Note, in accordance with the requirements of DTC,
the Issuer will cause the Trustee to authenticate an additional Note or additional Notes in the
appropriate principal amount such that neither this Note nor any other such Note may exceed an
aggregate principal amount of U.S.$500,000,000 at any time.

     This Note is a duly authorized issue of Notes of the Issuer, designated as its “JPR
PhaRMASM Senior Secured 14% Notes due 2020”, issued under the Indenture dated as of
March 9, 2011 (as amended, restated, supplemented or otherwise modified from time to time in
accordance with the terms thereof, the “Indenture”), by and between the Issuer and U.S.
Bank National Association, as trustee (including any successor appointed in accordance with the
terms of the Indenture, the “Trustee”). The Indenture also provides for the issuance of
Refinancing Notes and Subordinated Notes. All capitalized terms used in this Note and not defined
herein shall have the respective meanings assigned to such terms in the Indenture. Reference is
made to the Indenture and all indentures supplemental thereto for a statement of the respective
rights and obligations thereunder of the Issuer, the Trustee and the Noteholders. This Note is
subject to all terms of the Indenture.

A-1

 

     The Issuer will pay the Outstanding Principal Balance of this Note on or prior to the Final
Legal Maturity Date on the Payment Date specified in the Indenture, subject to the availability of
the Available Collections Amount therefor after making payments entitled to priority under Section
3.7 of the Indenture.

     The indebtedness evidenced by the Original Class A Notes is, to the extent and in the manner
provided in the Indenture, senior in right of payment to the right of payment of the Subordinated
Notes, and this Note is issued subject to such provisions. The maturity of this Note is subject to
acceleration upon the occurrence and during the continuance of the Events of Default specified in
the Indenture.

     The Issuer may redeem all or part of the Outstanding Principal Balance of this Note prior to
the Final Legal Maturity Date on any Redemption Date, in the amounts and under the circumstances
specified in the Indenture.

     Any amount of Premium or interest on this Note that is not paid when due shall, to the fullest
extent permitted by Applicable Law, bear interest (“Additional Interest”) at an interest
rate per annum equal to the Stated Rate of Interest from the date when due until such amount is
paid or duly provided for, compounded annually and payable on the next succeeding Payment Date,
subject to the availability of the Available Collections Amount therefor (and, to the extent
provided in Section 3.8, the Interest Reserve Account and the Capital Account) after making
payments entitled to priority under Section 3.7 of the Indenture.

     This Note is and will be secured by the Collateral and the Issuer Pledged Equity pledged as
security therefor as provided in the Indenture and the Pledge and Security Agreement, respectively.

     Subject to and in accordance with the terms of the Indenture, there will be distributed
annually from the Collection Account on each Payment Date commencing on September 1, 2011, to the
Person in whose name this Note is registered at the close of business on the Record Date with
respect to such Payment Date, in the manner specified in Section 3.7 of the Indenture, such
Person’s pro rata share (based on the aggregate percentage of the Outstanding Principal Balance of
the Original Class A Notes held by such Person) of the aggregate amount distributable to all
Noteholders of Original Class A Notes on such Payment Date.

     All amounts payable in respect of this Note shall be payable in dollars in the manner provided
in the Indenture to the Noteholder hereof on the Record Date relating to such payment. The final
payment with respect to this Note, however, shall be made only upon presentation and surrender of
this Note by the Noteholder or its agent at an office or agency of the Trustee or Paying Agent in
New York City. At such time, if any, as this Note is issued in the form of one or more Definitive
Notes (other than by reason of Section 2.5(d) of the Indenture), payments on a Payment Date shall
be made by check mailed to each Noteholder of such a Definitive Note on the applicable Record Date
at its address appearing on the Register maintained with respect to the Original Class A Notes.
Alternatively, upon application in writing to the Trustee or other Paying Agent, not later than the
applicable Record Date, by a Noteholder (but only if this Note has an Outstanding Principal Balance
of at least $5,000,000), any such payments shall be made by wire transfer to an account designated
by such Noteholder at a financial institution in New

A-2

 

York City; provided, that, in each
case, the final payment with respect to any such Definitive Note shall be made only upon
presentation and surrender of such Definitive Note by the Noteholder or its agent at an office or
agency of the Trustee or Paying Agent in New York City. Notwithstanding the foregoing, payments in
respect of this Note issued in the form of a Global Note (including principal, Premium, if any, and
interest) shall be made by wire transfer of immediately available funds to the account specified by
DTC. Any reduction in the Outstanding Principal Balance of this Note (or any one or more
predecessor Original Class A Notes) effected by any payments made on any Payment Date shall be
binding upon all future Noteholders of this Note and of any Original Class A Note issued upon the
registration of transfer of, in exchange or in lieu of or upon the refinancing of this Note,
whether or not noted hereon.

     The Noteholder of this Note agrees, by acceptance hereof, to pay over to the Trustee any money
(including principal, Premium, if any, and interest) paid to it in respect of this Note in the
event that the Trustee, acting in good faith, determines subsequently that such monies were not
paid in accordance with the priority of payment provisions of the Indenture or as a result of any
other mistake of fact or law on the part of the Trustee in making such payment.

     This Note is issuable only in registered form. A Noteholder or Beneficial Holder may transfer
this Note or a Beneficial Interest herein only by delivery of a written application to the
Registrar stating the name of the proposed transferee, a Confidentiality Agreement duly executed
and delivered to the Registrar by such transferee and otherwise complying with the terms of the
Indenture. No such transfer shall be effected until, and such transferee shall succeed to the
rights of a Noteholder only upon, final acceptance and registration of the transfer by the
Registrar in the Register. When this Note is presented to the Registrar with a request to register
the transfer or to exchange it for an equal principal amount of Original Class A Notes of other
authorized denominations, the Registrar shall register the transfer or make the exchange as
requested if its requirements for such transactions are met (including, in the case of a transfer,
that such Note is duly endorsed or accompanied by a written instrument of transfer in form
satisfactory to the Trustee and Registrar duly executed by the Noteholder thereof or by an attorney
who is authorized in writing to act on behalf of the Noteholder and that the transferee has
executed and delivered to the Registrar a Confidentiality Agreement). No service charge shall be
made for any registration of transfer or exchange of this Note, but the party requesting such new
Original Class A Note or Original Class A Notes may be required to pay a sum sufficient to cover
any transfer Tax or similar governmental charge payable in connection therewith.

     Prior to the registration of transfer of this Note, the Issuer and the Trustee may deem and
treat the Person in whose name this Note (as of the day of determination or as of such other date
as may be specified in the Indenture) is registered as the absolute owner and Noteholder hereof for
the purpose of receiving payment of all amounts payable with respect to this Note and for all other
purposes, and neither the Issuer nor the Trustee shall be affected by notice to the contrary.

     Subject to Section 3.7(b) of the Indenture, the Indenture permits the amendment or
modification of the Indenture and the Original Class A Notes by the Issuer with the consent of the
Noteholders of a majority of the Outstanding Principal Balance of the Notes (voting or acting as a
single class); provided, however, that if there shall be Notes of more than one
class Outstanding and if a proposed amendment, modification, consent or waiver shall directly
affect the rights of Noteholders of one or more, but less than all, of such classes, then the
consent only

A-3

 

of the Noteholders of a majority of the Outstanding Principal Balance of each affected
class of Notes, each voting or acting as a single class, shall be required; provided,
further, however, that no amendment or modification of the Indenture or the
Original Class A Notes may, without the consent of Noteholders of 100% of the Outstanding Principal
Balance of the class of Notes affected thereby, (i) reduce the percentage of Noteholders of any
such class of Notes required to take or approve any action under the Indenture, (ii) reduce the
amount or change the time of payment of any amount owing or payable with respect to any such class
of Notes (including pursuant to any Redemption) or change the rate of interest or change the manner
of calculation of interest payable with respect to any such class of Notes, (iii) alter or modify
in any adverse respect the provisions with respect to the Collateral or any Issuer Pledged
Collateral for the Notes, the provisions of the Pledge and Security Agreement with respect to the
related Issuer Pledged Collateral for the Notes or the manner of payment or the order of priorities
in which payments or distributions under the Indenture will be made as between the Noteholders of
such Notes and the Issuer or as among the Noteholders (including pursuant to Section 3.7 of the
Indenture), (iv) consent to any assignment of the Issuer’s rights to a party other than the Trustee
for the benefit of the Noteholders or (v) alter the provisions relating to the Interest Reserve
Account in a manner adverse to any Noteholder. Any such amendment or modification shall be binding
on every Noteholder hereof, whether or not notation thereof is made upon this Note.

     The subordination provisions contained in Article X of the Indenture may not be amended or
modified without the consent of Noteholders of 100% of the Outstanding Principal Balance of the
class of Notes affected thereby. In no event shall the provisions set forth in Section 3.7 of the
Indenture relating to the priority of payment of Expenses be amended or modified.

     The Indenture also contains provisions permitting the Noteholders of a majority of the
Outstanding Principal Balance of the Senior Class of Notes, on behalf of the Noteholders of all of
the Original Class A Notes, to waive compliance by the Issuer with certain provisions of the
Indenture and certain past defaults under the Indenture and their consequences. Any such consent
or waiver shall be conclusive and binding upon all present and future Noteholders of this Note and
of any Original Class A Note issued upon the registration of transfer of, in exchange or in lieu of
or upon the refinancing of this Note, whether or not notation of such consent or waiver is made
upon this Note.

     The Original Class A Notes are issuable only in registered form in denominations as provided
in the Indenture, subject to certain limitations therein set forth.

     THIS NOTE SHALL BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH THE INTERNAL SUBSTANTIVE LAWS
OF THE STATE OF NEW YORK WITHOUT REFERENCE TO THE RULES THEREOF RELATING TO CONFLICTS OF LAW OTHER
THAN SECTION 5-1401 OF THE GENERAL OBLIGATIONS LAW OF THE STATE OF NEW YORK, AND THE OBLIGATIONS,
RIGHTS AND REMEDIES HEREUNDER SHALL BE DETERMINED IN ACCORDANCE WITH SUCH LAWS.

     The enforceability against the Issuer of the obligations of the Issuer under the Indenture and
under the Notes shall be limited to the assets of the Issuer, whether tangible or intangible, real
or personal (including the Collateral) and the proceeds thereof. Once all such assets have

A-4

 

been
realized upon and such assets (and proceeds thereof) have been applied in accordance with Article
III of the Indenture, any outstanding obligations of the Issuer shall be extinguished. Each of the
parties to the Indenture shall take no action against any employee, director, officer or
administrator of the Issuer, an Equityholder or the Trustee in relation to the Indenture;
provided, that nothing therein shall limit the Issuer (or its permitted successors or
assigns, including any party thereto that becomes such a successor or assign) from pursuing claims,
if any, against any such Person. The provisions of Section 12.14 of the Indenture shall survive
termination of the Indenture; provided, further, that the foregoing shall not in
any way limit, impair or otherwise affect any rights of the Trustee or the Noteholders to proceed
against any such Person (a) for intentional and willful fraud or intentional and willful
misrepresentations on the part of or by such Person or (b) for the receipt of any distributions or
payments to which the Issuer or any successor in interest is entitled, other than distributions
expressly permitted pursuant to the Indenture and the other Deal Documents.

     Unless the certificate of authentication hereon has been executed by the Trustee whose name
appears below by manual signature, this Note shall not be entitled to any benefit under the
Indenture, or be valid or obligatory for any purpose.

A-5

 

     IN WITNESS WHEREOF, the Issuer has caused this Note to be signed manually or by facsimile by
its duly authorized Manager.

	 	 	 	 	 
	Date: March 9, 2011 	 JPR ROYALTY SUB LLC

By: BioCryst Pharmaceuticals, Inc., its Manager

 	 
	 	By:  	 	 
	 	 	Name:  	 	 
	 	 	Title:  	 	 
	 

TRUSTEE’S CERTIFICATE OF AUTHENTICATION

     This Note is one of the JPR PhaRMASM Senior Secured 14% Notes due 2020 designated
above and referred to in the within-mentioned indenture.

	 	 	 	 	 
	Date: March 9, 2011 	U.S. BANK NATIONAL ASSOCIATION,

as Trustee

 	 
	 	By:  	 	 
	 	 	Authorized Signatory 	 
	 	 	 	 

A-6

 

	 	 	 	 	 

FORM OF TRANSFER NOTICE

     FOR VALUE RECEIVED the undersigned registered holder hereby sell(s), assign(s) and transfer(s)
unto

Insert Taxpayer Identification No. _____________________

 
 (Please print or typewrite name and address including zip code of assignee)

the within Note and all rights thereunder, hereby irrevocably constituting and appointing
_________________________________________ attorney to transfer said Note on the books of the Issuer
with full power of substitution in the premises.

	 	 	 

	 
	 	 
	Date
	 	Signature of Transferor

NOTE: The signature to this assignment must correspond with the name as written upon the face of
the within-mentioned instrument in every particular, without alteration or any change whatsoever.

[THE FOLLOWING PROVISIONS TO BE INCLUDED ON ALL NOTES]

     In connection with any transfer of the within-mentioned Note, the undersigned confirms without
utilizing any general solicitation or general advertising that:

[Check One]

__(a) the within-mentioned Note is being transferred in compliance with the exemption from
registration under the Securities Act provided by Rule 144A thereunder

__(b) the within-mentioned Note is being transferred other than in accordance with clause (a) above
and documents are being furnished that comply with the conditions of transfer set forth in the
within-mentioned Note and the Indenture

If neither of the foregoing boxes is checked, the Trustee or other Registrar shall not be obligated
to register the within-mentioned Note in the name of any Person other than the Noteholder hereof
unless and until the conditions to any such transfer of registration set forth herein and in
Section 2.11 of the Indenture shall have been satisfied.

	 	 	 

	 
	 	 
	Date
	 	NOTICE: The signature to this assignment must correspond with the name as written upon the
face of the within-mentioned instrument in every particular, without alteration or any change
whatsoever.

A-7

 

TO BE COMPLETED BY PURCHASER IF CLAUSE (a) ABOVE IS CHECKED.

     The undersigned represents and warrants that it is purchasing the within-mentioned Note for
its own account or an account with respect to which it exercises sole investment discretion and
that each of it and any such account is a “qualified institutional buyer” within the meaning of
Rule 144A and is aware that the sale to it is being made in reliance on Rule 144A and acknowledges
that it has received such information regarding the Issuer as the undersigned has requested
pursuant to Rule 144A or has determined not to request such information and that it is aware that
the transferor is relying upon the undersigned’s foregoing representations in order to claim the
exemption from registration provided by Rule 144A and has executed and delivered to the Registrar a
Confidentiality Agreement.

Dated: __________

	 	 	 	 	 
	 	
Executive Officer

 	 

A-8

 

	 	 	 	 	 

SCHEDULE I

JPR ROYALTY SUB LLC

JPR PhaRMASM Senior Secured 14% Notes due 2020

No. ____

	 	 	 	 	 	 	 
	 	 	 	 	Notation Explaining	 	Authorized Signature
	 	 	 	 	Principal Amount	 	of Trustee or
	Date	 	Principal Amount	 	Recorded	 	Custodian
	 	 	 	 	 	 	 

A-9

 

EXHIBIT B

FORM OF CONFIDENTIALITY AGREEMENT

No. ____

BioCryst Pharmaceuticals, Inc.

4505 Emperor Boulevard, Suite 200

Durham, North Carolina 27703

JPR Royalty Sub LLC

c/o BioCryst Pharmaceuticals, Inc.

4505 Emperor Boulevard, Suite 200

Durham, North Carolina 27703

__________, 20__

CONFIDENTIALITY AGREEMENT

     In connection with our possible interest in the purchase of the JPR PhaRMASM Senior
Secured Notes (the “Notes”) issued by JPR Royalty Sub LLC, a Delaware limited liability
company (the “Company”) (the “Transaction”), we have requested a copy of the
Private Placement Memorandum relating to the Notes (the “Memorandum”). In addition to
receiving the Memorandum, we may also request that you or your directors, officers, managers,
members, partners, employees, affiliates, assigns, representatives (including, without limitation,
financial advisors, attorneys and accountants), agents or similar persons (collectively, “your
Representatives”) furnish us or our directors, officers, managers, members, partners,
employees, affiliates, assigns, representatives (including, without limitation, financial advisors,
attorneys and accountants), agents or similar persons (collectively, “our Representatives”)
with certain Confidential Information (as defined in the Indenture described below) and with
certain other information relating to the Company, the Transaction and the rights being acquired by
the Company from BioCryst Pharmaceuticals, Inc., a Delaware corporation (the “Seller”).
All such information (whether written, visual or oral, and whether tangible or electronic)
furnished on or after the date hereof by you or your Representatives (including any such
information provided in a dataroom via IntraLinks or otherwise) to us or our Representatives,
including, without limitation, the Memorandum, any agreements between the Seller and Shionogi &
Co., Ltd., any royalty reports required to be delivered thereunder, any agreements between the
Seller and The UAB Research Foundation (“UAB RF”) and any materials containing, based on or
derived from any such information (including, without limitation, any financial models or other
analyses, compilations, forecasts, studies or other documents based thereon) prepared by us or our
Representatives in connection with our or our Representatives’ review of, or our interest in, the
Transaction is hereinafter referred to as the “Information”. The term Information will
not, however, include information that (i) is already known by us at the time that such information
is disclosed (unless such information was disclosed to us under a confidentiality agreement with
you), (ii) is or thereafter becomes available in the public domain, other than by breach by us or
our Representatives of our obligations hereunder or (iii) is obtainable by us from another source
without breach of such source’s obligations of confidentiality to you.

B-1

 

     As a condition to receiving the Information, we hereby agree as follows:

     1. We and our Representatives hereby agree (i) to keep the Information confidential and to use
at least the same level of care in safeguarding such Information as we use with our own
confidential information, and in no event less than reasonable care under the circumstances, (ii)
that the Information will be used solely for the purpose of evaluating, entering into, monitoring
or enforcing the Transaction, (iii) not to, without your prior written consent, disclose any
Information in any manner whatsoever, and (iv) not to decompile, disassemble or reverse engineer
the Information; provided, however, that we may reveal the Information to (a) our
Representatives who need to know the Information for the purpose of evaluating, entering into,
monitoring or enforcing the Transaction or (b) third parties in order to comply with any applicable
law, rule, regulation or legal process or pursuant to requests of governmental authorities or
regulatory agencies having oversight over us or our Representatives, and only after compliance with
paragraph 3 below, provided, that all of such persons listed in clause (a) above shall
agree to keep such Information confidential, and only to use such Information, on terms that are
substantially the same as the terms we are subject to herein, and, provided,
further, that we shall be wholly responsible for the full compliance of such
confidentiality agreement or confidentiality undertaking by any of the persons listed in clause (a)
above to which we disclosed Information. Notwithstanding and without limitation of the foregoing,
we and our Representatives agree not to reveal Information to advisors who are principally engaged
in the business of investment banking, capital markets, securitization of financial assets or in
any other business that may include the provision of capital without the prior written consent of
your Representative, Morgan Stanley & Co. Incorporated (“Morgan Stanley”).

     2. We and our Representatives agree, whether or not the Transaction is consummated, not to
(except as required by applicable law, rule, regulation or legal process or pursuant to requests of
governmental authorities or regulatory agencies having oversight over us or our Representatives,
and only after compliance with paragraph 3 below), without your prior written consent, disclose to
any person the fact that the Information or the Transaction exists or has been made available, that
we are considering the Transaction, that (if prior to consummation of the Transaction) you are
considering the Transaction, or that discussions or negotiations are taking or have taken place
concerning the Transaction or any term, condition or other fact relating to the Transaction or such
discussions or negotiations, including, without limitation, the status thereof.

     3. In the event that we or any of our Representatives are required by applicable law, rule,
regulation or legal process or pursuant to requests of governmental authorities or regulatory
agencies having oversight over us or our Representatives to disclose any of the Information, we
agree to notify you promptly (unless such notice is not permitted by applicable law, rule or
regulation) so that you may seek, at your own expense, but with our cooperation, a protective order
or other appropriate remedy or, in your sole discretion, waive compliance with the terms of this
Confidentiality Agreement. In the event that no such protective order or other remedy is obtained,
or that you do not waive compliance with the terms of this Confidentiality Agreement, we agree to
furnish only that portion of the Information that we are advised by counsel (which may be internal
counsel) is legally required and will exercise all commercially reasonable efforts to obtain
reliable assurance that confidential treatment will be accorded the Information.

B-2

 

     4. If we determine not to proceed with the Transaction or we cease to have an interest arising
from the Transaction, we will promptly inform you in writing (including, without limitation, via
email) of that decision or event and, in that case, and at any time upon your request or the
request of any of your Representatives, we and our Representatives agree to (i) promptly deliver to
you all copies of the Information in our possession (except as described in the following proviso),
(ii) promptly destroy all copies of any written Information (whether in tangible or electronic
form, or otherwise) that we and our Representatives have created, including, without limitation,
any notes we have taken on any discussions with you or your Representatives, and upon your request
such destruction shall be certified in writing (including, without limitation, via email) to you by
an authorized officer supervising such destruction (provided in each case that an appropriate
person within our organization may retain one copy of the Information, subject to the provisions of
this Confidentiality Agreement, if required to comply with internal record retention policies or
regulatory considerations, in which case, regardless of paragraph 16 below, the confidentiality
provisions of this Confidentiality Agreement will continue to apply to such Information for so long
as it is retained by such person or any other of our Representatives) and (iii) certify that
clauses (i) and (ii) above have been complied with. Any visual, oral or other Information not
returned to you or destroyed in accordance with the preceding sentence will continue to be subject
to the terms of this Confidentiality Agreement, regardless of paragraph 16 below.

     5. We acknowledge that you have not updated, and have no obligation to update, the Memorandum
in any respect for events, developments or circumstances. We further acknowledge that neither you
nor any of your Representatives, nor any of your or their respective officers, directors, managers,
members, partners, employees, agents or controlling persons within the meaning of Section 20 of the
Securities Exchange Act of 1934, as amended, makes any express or implied representation or
warranty as to the accuracy or completeness of the Information, and we agree that no such person
will have any liability relating to the Information or for any errors therein or omissions
therefrom. We further agree that we are not entitled to rely on the accuracy or completeness of
the Information and that we will be entitled to rely solely on such representations and warranties
as may be included in any definitive written agreement with respect to the Transaction, subject to
such limitations and restrictions as may be contained therein.

     6. We acknowledge that we are aware of the restrictions imposed by the United States
securities laws on the purchase or sale of securities of an issuer (such as the Seller) or an
affiliate or controlling person of the issuer while in possession of material, non-public
information and on the communication of such information to any other person. We represent that we
maintain effective internal procedures with respect to maintaining the confidentiality and use of
the Information, that we will not trade in securities of, or derivative instruments relating to,
the Seller while in possession of material nonpublic information relating to the Seller, and that
we will not otherwise use the Information for any purpose in violation of United States securities
laws or any other applicable laws. We further represent that we are a qualified institutional
buyer (as defined in Rule 144A under the Securities Act of 1933, as amended (the “Securities
Act”)) or a non-U.S. person within the meaning of Regulation S under the Securities Act that is
also an institutional accredited investor (as defined in subparagraph (a) (1), (2), (3) or (7) of
Rule 501 under the Securities Act of 1933, as amended) and acknowledge and agree that,

B-3

 

by our
purchase of any Notes, we will be deemed to have made the representations, agreements and
acknowledgments set forth in the Memorandum under “Transfer Restrictions”.

     7. We represent and warrant that (i) we are not, and will not become, a partnership,
Subchapter S corporation or grantor trust for U.S. federal income tax purposes or (ii) we are or
may become a partnership, Subchapter S corporation or grantor trust for U.S. federal income tax
purposes but (A) none of the direct or indirect beneficial owners of any of our interests have
allowed or caused, or will allow or cause, 50% or more of the value of such interests to be
attributable to the ownership of Notes plus the ownership, if any, of equity of the Company or (B)
such partnership, Subchapter S corporation or grantor trust was not formed with a principal purpose
of permitting the Company to satisfy the 100-partner limitation in Treasury Regulation Section
1.7704-1(h)(1)(ii).

     8. We agree that, at any time prior to your consummation of the Transaction, (i) you reserve
the right, in your sole discretion, to change the terms of the Transaction at any time without
prior notice to us or any other person, to reject any and all proposals or offers made by us or any
of our Representatives with regard to the Transaction, and to terminate discussions and
negotiations with us at any time and for any reason, and (ii) except to the extent set forth in any
definitive written agreement concerning the Transaction, you will not have any liability to us with
respect to the Transaction, whether by virtue of this Confidentiality Agreement, any other written
or oral expression with respect to the Transaction or otherwise.

     9. We acknowledge that remedies at law may be inadequate to protect you against any actual or
threatened breach of this Confidentiality Agreement by us or our Representatives, and, without
prejudice to any other rights and remedies otherwise available to you, we agree to permit you to
seek the granting of injunctive or other equitable relief in your favor without proof of actual
damages.

     10. We acknowledge and agree that each of the Seller, Shionogi & Co., Ltd., UAB RF and Morgan
Stanley is a third party beneficiary of this Confidentiality Agreement and shall have the right to
enforce any provision of this Confidentiality Agreement.

     11. We acknowledge and agree that neither this Confidentiality Agreement nor any disclosure of
Information made hereunder by you shall be construed, deemed or interpreted, by implication or
otherwise, to vest in us or our Representatives any license or other ownership rights in, to or
under any of such Information or other copyrights, intellectual property, know-how, moral rights,
trade secrets, trademark rights or other proprietary rights whatsoever.

     12. We agree that no failure or delay by you in exercising any right, power or privilege
hereunder will operate as a waiver thereof, nor will any single or partial exercise thereof
preclude any other or further exercise thereof or the exercise of any right, power or privilege
hereunder.

     13. This Confidentiality Agreement shall be binding upon and inure to the benefit of the
parties hereto and their respective successors and assigns. We agree that we will not assign this
Confidentiality Agreement without your prior written consent.

B-4

 

     14. This Confidentiality Agreement shall be governed by, and construed, interpreted and
enforced in accordance with, the laws of the State of New York, without giving effect to the
principles of conflicts of law thereof (other than the provisions of Section 5-1401 of the General
Obligations Law of the State of New York).

     15. This Confidentiality Agreement contains the entire agreement between you and us, and
supersedes all prior agreements and understandings, whether written or oral, between you and us,
concerning the confidentiality of the Information, and no modifications of this Confidentiality
Agreement or waiver of the terms and conditions hereof will be binding upon you or us, unless
approved in writing by each of you and us.

     16. This Confidentiality Agreement will terminate (i) if we do not proceed with the
Transaction, 24 months after the date hereof, and (ii) if we do proceed with the Transaction, 24
months from the date we cease to have an interest arising from the Transaction, whether through a
sale of our interest, the maturity or repayment of our interest or otherwise.

     17. If we propose to purchase, transfer, sell or otherwise dispose of any of our interest at
any time, we agree to (i) abide by any transfer restrictions described in the Memorandum, (ii)
inform any proposed transferee of such interest of any such transfer restrictions, including,
without limitation, any requirement that such proposed transferee execute a confidentiality
agreement, and (iii) not furnish any Information to such proposed transferee. We acknowledge that
the servicer for the Transaction shall be responsible for the delivery of all Information to any
such prospective transferee following execution by such prospective transferee of an appropriate
confidentiality agreement.

     18. This Confidentiality Agreement may be executed by facsimile signature and such facsimile
signature shall be deemed an original. This Confidentiality Agreement may be executed in one or
more counterparts by the parties hereto, and each such counterpart shall be considered an original
and all such counterparts shall constitute one and the same instrument.

     In accordance with Section 2.11(j) of the Indenture that will have been entered into by and
between you and U.S. Bank National Association, a national banking association, as trustee (the
“Indenture”), we will provide a fully executed copy of this Confidentiality Agreement to
the Registrar (as defined in the Indenture) promptly after executing this Confidentiality
Agreement.

B-5

 

	 	 	 	 	 
	 	Very truly yours,

[Please insert prospective purchaser’s name on line above]

 	 
	 	By:  	 	 
	 	 	Name:  	 	 
	 	 	Title:
Address:  	 	 
	 

Accepted and agreed as of the date

first written above:

	 	 	 	 	 
	 	BIOCRYST PHARMACEUTICALS, INC.

 	 
	 	By:  	 	 
	 	 	Name:  	 	 
	 	 	Title:  	 	 
	 
	 	JPR ROYALTY SUB LLC

 	 
	 	By:  	BioCryst Pharmaceuticals, Inc.,
     as authorized signatory for JPR Royalty Sub LLC
 	 
	 	 	 
	 	By:  	 	 
	 	 	Name:  	 	 
	 	 	Title:  	 	 

B-6

 

	 	 	 	 	 

EXHIBIT C

AGENTS FOR SERVICE OF PROCESS

	 	 	 	 	 
	Party	 	Jurisdiction	 	Appointed Agent
	JPR Royalty Sub LLC

	 	Delaware
	 	Corporation Service Company

C-1

 

EXHIBIT D

COVERAGE OF DISTRIBUTION REPORT

	(i)	 	With respect to the current Payment Date, (A) the balances on deposit in the Collection
Account and any other Account established under the Indenture on the Calculation Date
immediately preceding the prior Payment Date (or, with respect to the first Payment Date, on
the Closing Date) (the “Preceding Calculation Date”), (B) the aggregate amounts of
deposits into and withdrawals from the Collection Account and any other Account established
under the Indenture from but excluding the Preceding Calculation Date to and including the
Calculation Date immediately preceding the Payment Date (the “Current Calculation
Date”) and (C) the balances on deposit in the Collection Account and any other Account
established under the Indenture on the Current Calculation Date

	(ii)	 	Analysis of currency hedge and currency exchange transactions from the Preceding Calculation
Date to the Current Calculation Date

	(iii)	 	Analysis of Collection Account activity from the Preceding Calculation Date to the Current
Calculation Date

	 	 	Balance on the Preceding Calculation Date

	 	 	Collections from but excluding the Preceding Calculation Date to and including the Current
Calculation Date (“Current Collections”)

	 	 	Aggregate Note payments from but excluding the Preceding Calculation Date to and including
the Current Calculation Date, including pursuant to Section 2.5(e)

	 	 	Expense payments payable on the Current Calculation Date, including normal and routine bank
fees (“Current Expenses”)

	 	 	Payments to the Seller pursuant to Section 3.4

	 	 	Balance on the Current Calculation Date

	(iv)	 	Amount, if any, to be transferred from the Interest Reserve Account to the Collection Account
on the current Payment Date

	(v)	 	Payments on the current Payment Date
	 
	 	 	Current Expenses

Interest Amount

Additional Interest, if any

Payments to the Interest Reserve Account, if any

Principal payments, if any
	 
	(vi)	 	Outstanding Principal Balance

	 	 	Opening Outstanding Principal Balance

Principal payments, if any, made on the current Payment Date

Closing Outstanding Principal Balance

D-1

 

	(vii)	 	Amount distributed to the Issuer from the Collection Account, if any, with respect to the
current Payment Date

	(viii)	 	A withholding obligation may be included

	(ix)	 	Appropriate modifications will be made to contemplate any Refinancing Notes and/or
Subordinated Notes

D-2

 

EXHIBIT E

UCC FINANCING STATEMENTS

	1.	 	A Form UCC-1 Financing Statement will be filed with the Secretary of State of the State of
Delaware naming the Issuer as debtor and the Trustee as secured party.

E-1

 

EXHIBIT F

FORM OF CERTIFICATE OF EUROCLEAR OR CLEARSTREAM FOR PERMANENT REGULATION S GLOBAL NOTE

__________, 20__

U.S. Bank National Association,

     as Trustee

One Federal Street, 3rd Floor

Boston, Massachusetts 02110

Attention: Corporate Trust Services (JPR Royalty Sub LLC / BioCryst)

JPR Royalty Sub LLC

c/o BioCryst Pharmaceuticals, Inc.

4505 Emperor Boulevard, Suite 200

Durham, North Carolina 27703

Attention: General Counsel

	 	Re: 	 	 JPR Royalty Sub LLC (the “Issuer”)

Ladies and Gentlemen:

     This letter relates to U.S.$__________ principal amount of JPR PhaRMASM Senior
Secured 14% Notes due 2020 of the Issuer (the “Notes”) represented by a Note that bears a
legend (the “Legended Note”) outlining restrictions upon transfer of such Legended Note.
Pursuant to Section 2.1 of the Indenture dated as of March 9, 2011 (the “Indenture”)
relating to the Notes and certain other classes of notes of the Issuer, we hereby certify that we
are (or we will hold such securities on behalf of) an Institutional Accredited Investor (as defined
in the Indenture) outside the United States to whom the Notes may be transferred in accordance with
Rule 904 of Regulation S promulgated under the U.S. Securities Act of 1933, as amended
(“Regulation S”). Accordingly, you are hereby requested to exchange the Legended Note for
a Permanent Regulation S Global Note (as defined in the Indenture) representing an identical
principal amount of Notes, all in the manner provided for in the Indenture.

     Each of you is entitled to rely upon this letter and is irrevocably authorized to produce this
letter or a copy hereof to any interested party in any administrative or legal proceeding or
official inquiry with respect to the matters covered hereby. Certain terms used in this
certificate have the meanings set forth in Regulation S.

	 	 	 	 	 
	 	Very truly yours,

[Euroclear Bank S.A./N.V.][Clearstream Banking]

 	 
	 	By:  	 	 
	 	 	Authorized Signatory 	 
	 	 	 	 

F-1

 

	 	 	 	 	 

EXHIBIT G

FORM OF CERTIFICATE OF BENEFICIAL OWNER OF TEMPORARY
REGULATION S GLOBAL NOTE

Euroclear Bank S.A./N.V.

[Address]

AND/OR

Clearstream Banking

[Address]

	 	Re: 	 	 JPR Royalty Sub LLC (the “Issuer”)

     Reference is hereby made to the Indenture, dated as of March 9, 2011 (the
“Indenture”), made by and between the Issuer and U.S. Bank National Association, as trustee
(the “Trustee”). Capitalized terms used but not defined herein shall have the meanings
given to them in the Indenture.

     This
letter relates to
U.S.$__________ principal
amount of JPR
PhaRMASM Senior
Secured 14% Notes due 2020 that are held in the form of a Beneficial Interest in the Temporary
Regulation S Global Note (CUSIP No. __________) through DTC by the undersigned (the
“Holder”) in the name of __________. The Holder of such Temporary Regulation S Global Note
hereby requests the receipt of payments due and payable on the applicable Payment Date pursuant to
Section 2.5 of the Indenture.

     The Holder hereby represents and warrants that it (i) is an Institutional Accredited Investor,
(ii) is not a U.S. Person, (iii) does not hold the above-referenced Temporary Regulation S Global
Note for the account or benefit of a U.S. Person (other than a distributor) and (iv) has executed
and delivered to the Registrar a Confidentiality Agreement. Certain terms in this certificate not
otherwise defined in the Indenture have the meanings given to them in Regulation S.

     This certificate and the statements contained herein are made for your benefit and the benefit
of the Paying Agent.

	 	 	 	 	 
	 	[Name of Holder]

 	 
	 	By:  	 	 
	 	 	Name:  	 	 
	 	 	Title:  	 	 

G-1

 

	 	 	 	 	 

EXHIBIT H

FORM OF CERTIFICATE OF EUROCLEAR OR CLEARSTREAM FOR PAYMENTS

	 

	U.S. Bank National Association,

     as Paying Agent 

One Federal Street, 3rd Floor 

Boston, Massachusetts 02110

Attention: Corporate Trust Services (JPR Royalty Sub LLC / BioCryst)

	 	Re: 	 	 JPR Royalty Sub LLC (the “Issuer”)

     Reference is hereby made to the Indenture, dated as of March 9, 2011 (the
“Indenture”), made by and between the Issuer and U.S. Bank National Association, as trustee
(the “Trustee”). Capitalized terms used but not defined herein shall have the meanings
given to them in the Indenture.

     This
letter relates to
U.S.$__________ principal
amount of JPR
PhaRMASM Senior
Secured 14% Notes due 2020 that are held in the form of a Beneficial Interest in the Temporary
Regulation S Global Note (CUSIP No. __________) through DTC by the undersigned (the
“Holder”) in the name of __________. Certain Holders of the Beneficial Interests in such
Temporary Regulation S Global Note have requested the receipt of payments due and payable on the
applicable Payment Date pursuant to Section 2.5 of the Indenture.

     We have received from such Holders certifications to the effect that they (i) are
Institutional Accredited Investors, (ii) are not U.S. Persons, (iii) do not hold the
above-referenced Temporary Regulation S Global Note for the account or benefit of U.S. Persons
(other than distributors) and (iv) have executed and delivered to the Registrar a Confidentiality
Agreement. Certain terms in this certificate not otherwise defined in the Indenture have the
meanings given to them in Regulation S.

     Accordingly, the Holders of the Beneficial Interests in the Temporary Regulation S Global Note
are entitled to receive interest, principal and Premium, if any, in accordance with the terms of
the Indenture in the amount of U.S.$__________.

	 	 	 	 	 
	 	[Clearstream Banking][Euroclear Bank S.A./N.V.]

 	 
	 	By:  	 	 
	 	 	Name:  	 	 
	 	 	Title:  	 	 

H-1

 

	 	 	 	 	 

EXHIBIT I

FORM OF CERTIFICATE OF PROPOSED TRANSFEROR

__________, 20__

U.S. Bank National Association,

     as Registrar

One Federal Street, 3rd Floor

Boston, Massachusetts 02110

Attention: Corporate Trust Services (JPR Royalty Sub LLC / BioCryst)

JPR Royalty Sub LLC

c/o BioCryst Pharmaceuticals, Inc.

4505 Emperor Boulevard, Suite 200

Durham, North Carolina 27703

Attention: General Counsel

	 	Re: 	 	 JPR Royalty Sub LLC (the “Issuer”)

Ladies and Gentlemen:

     In connection with our proposed sale of U.S.$__________ aggregate principal amount of JPR
PhaRMASM Senior Secured 14% Notes due 2020 of the Issuer (the “Notes”), we
confirm that such sale has been effected pursuant to and in accordance with Regulation S under the
U.S. Securities Act of 1933, as amended (“Regulation S”) and, accordingly, we represent
that:

     (1) the offer of the Notes was not made to a person in the U.S.;

     (2) at the time the buy order was originated, the transferee was an institutional accredited
investor (as defined in subparagraph (a) (1), (2), (3) or (7) of Rule 501 under the U.S. Securities
Act of 1933, as amended) outside the U.S. or we and any person acting on our behalf reasonably
believed that the transferee was an institutional accredited investor outside the U.S.;

     (3) no directed selling efforts have been made by us in the U.S. in contravention of the
requirements of Rule 903(b) or Rule 904(b) of Regulation S, as applicable;

     (4) the transaction is not part of a plan or scheme to evade the registration requirements of
the U.S. Securities Act of 1933; and

     (5) the transferee has entered into the confidentiality agreement required in connection with
the purchase of the Notes.

     Each of you is entitled to rely upon this letter and is irrevocably authorized to produce this
letter or a copy hereof to any interested party in any administrative or legal proceeding or
official inquiry with respect to the matters covered hereby. Certain terms used in this
certificate have the meanings set forth in Regulation S.

I-1

 

	 	 	 	 	 
	 	Very truly yours,

[Name of Transferor]

 	 
	 	By:  	 	 
	 	 	Authorized Signatory 	 
	 	 	 	 

I-2

 

	 	 	 	 	 

EXHIBIT J

FORM OF CERTIFICATE OF CERTAIN PROPOSED INSTITUTIONAL

ACCREDITED INVESTOR TRANSFEREES

__________, 20__

U.S. Bank National Association,

      as Registrar

One Federal Street, 3rd Floor

Boston, Massachusetts 02110

Attention: Corporate Trust Services (JPR Royalty Sub LLC / BioCryst)

JPR Royalty Sub LLC

c/o BioCryst Pharmaceuticals, Inc.

4505 Emperor Boulevard, Suite 200

Durham, North Carolina 27703

Attention: General Counsel

Ladies and Gentlemen:

     In connection with our proposed purchase of Notes (the “Notes”) of JPR Royalty Sub LLC
(the “Issuer”), we confirm that:

     1. We have duly executed and delivered to the Registrar (as defined in that certain Indenture
dated as of March 9, 2011 (the “Indenture”) by and between the Issuer and U.S. Bank
National Association, as trustee, as amended, restated, supplemented or otherwise modified from
time to time in accordance with the terms thereof) a Confidentiality Agreement and have
subsequently received a copy of the Private Placement Memorandum dated March 1, 2011 (the
“Memorandum”) relating to the Notes and such other information as we deem necessary in
order to make our investment decision. We acknowledge that we have read and agreed to the matters
stated in the section entitled “Transfer Restrictions” of such Memorandum and the restrictions on
duplication and circulation of such Memorandum.

     2. We understand that any subsequent transfer of the Notes is subject to certain restrictions
and conditions set forth in the Memorandum under “Transfer Restrictions” and the undersigned agrees
to be bound by, and not to resell, pledge or otherwise transfer the Notes except in compliance
with, such restrictions and conditions and the U.S. Securities Act of 1933, as amended (the
“Securities Act”).

     3. We understand that the offer and sale of the Notes have not been registered under the
Securities Act, that the Notes will only be in the form of definitive physical certificates and
that the Notes may not be offered or sold except as permitted in the following sentence. We agree,
on our own behalf and on behalf of any accounts for which we are acting as hereinafter stated,
that, if we should sell any Notes in the future, we will do so only (1) (A) to the Issuer or any
subsidiary thereof, (B) in accordance with Rule 144A under the Securities Act to a qualified
institutional buyer (as defined therein), (C) to an institutional accredited investor (as defined
in Rule 501(a)(1), (2), (3) or (7) of Regulation D under the Securities Act) (“Institutional

J-1

 

Accredited Investor”) that, prior to such transfer, furnishes to the Trustee (as defined in the
Indenture) a signed letter containing certain representations and agreements relating to the
restrictions on transfer of the Notes (the form of which letter can be obtained from the Trustee)
and an opinion of counsel acceptable to the Issuer that such transfer is in compliance with the
Securities Act, (D) to an Institutional Accredited Investor in an offshore transaction in
compliance with Rule 904 of Regulation S under the Securities Act or (E) to an Institutional
Accredited Investor after the relevant time period referred to in Rule 144 under the Securities Act
expires, and we further agree to provide to any entity purchasing any of the Notes from us a notice
advising such purchaser that resales of the Notes are restricted as stated herein and (2) in each
case, in accordance with any applicable securities laws of any state in the U.S. or any other
applicable jurisdiction and in accordance with the legend to be set forth in the Notes, which will
reflect the substance of this paragraph.

     4. We understand that, on any proposed resale of any Notes, we will be required to furnish to
the Issuer and the Trustee such certifications, legal opinions and other information as the Issuer
and the Trustee may reasonably require to confirm that the proposed sale complies with the
foregoing restrictions. We further understand that a confidentiality agreement is required under
the Indenture to be executed and delivered by any proposed transferee to whom we wish to sell any
Notes.

     5. We are an Institutional Accredited Investor and have such knowledge and experience in
financial and business matters as to be capable of evaluating the merits and risks of our
investment in the Notes, and we and any accounts for which we are acting are able to bear the
economic risks of our or their investment.

     6. We are acquiring the Notes purchased by us for our own account or for one or more accounts
(each of which is an Institutional Accredited Investor) as to each of which we exercise sole
investment discretion.

     7. We are not acquiring the Notes with a view to distribution thereof or with any present
intention of offering or selling the Notes, except as permitted above, provided that the
disposition of our property and property of any accounts for which we are acting as fiduciary shall
remain at all times within our control.

     You, the Issuer and the Trustee are entitled to rely upon this letter and are irrevocably
authorized to produce this letter or a copy hereof to any interested party in any administrative or
legal proceeding or official inquiry with respect to the matters covered hereby.

	 	 	 	 	 
	 	Very truly yours,

 	 
	 	By:  	 	 
	 	 	Name:  	 	 
	 	 	Title 	 

J-2

 

	 	 	 	 	 

EXHIBIT K

FORM OF PORTFOLIO INTEREST CERTIFICATE

________________________________ hereby certifies that:

	1.	 	It is (one must be checked):

	 	(1)	 	____ a natural individual person;
	 
	 	(2)	 	____ treated as a corporation for U.S. federal income tax purposes;
	 
	 	(3)	 	____ disregarded for U.S. federal income tax purposes (in which
case a copy of this certificate is completed and signed by its sole beneficial
owner); or
	 
	 	(4)	 	____ treated as a partnership for U.S. federal income tax
purposes (in which case each partner also has completed as to itself and signed
a copy of this certificate and an appropriate IRS Form W-8, a copy of each of
which is attached, or, if applicable, has completed as to itself and signed an
IRS Form W-9, a copy of which is attached).

	2.	 	It is not a bank, as such term is used in Section 881(c)(3)(A) of the Internal
Revenue Code of 1986, as amended (the “Code”).
	 
	3.	 	It is not a 10-percent shareholder of JPR Royalty Sub LLC (the
“Issuer”) or BioCryst Pharmaceuticals, Inc. (the “Equityholder”) within
the meaning of Section 871(h)(3) of the Code or Section 881(c)(3)(B) of the Code.
	 
	4.	 	It is not a controlled foreign corporation that is related to the Issuer or the
Equityholder within the meaning of Section 881(c)(3)(C) of the Code.
	 
	5.	 	Amounts received by it on the JPR PhaRMASM Senior Secured 14% Notes
due 2020 are not effectively connected with its conduct of a trade or business in the
United States.

	 	 	 	 	 
	 	[Fill in name of holder]

 	 
	 	By:  	 	 
	 	 	Name:  	 	 
	 	 	Title:
Date:  	 	 
	 

K-1

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