Document:

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                                                                 EXHIBIT 10.34.4

BEBIG GmbH                        Amendment IV
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                                  Amendment IV

          Amendment to the Facility Set-Up and Contract Manufacturing
                        Agreement and License Agreement

                                    between

                            RMS Medical Systems Inc.
                                hereafter "RMS"
                   Located at 13700 Alton Parkway, Suite 160,
                       in Irvine, California, 92618, USA

                                      and

                    BEBIG Isotopen-und Medizintechnik GmbH,
                               hereafter "BEBIG"
                       located at Robert-Rossle-Str. 10,
                           in D-13125 Berlin, Germany

BACKGROUND

RMS and BEBIG have signed a FACILITY SET-UP AND CONTRACT MANUFACTURING
AGREEMENT including the ADDENDUM TO FACILITY SET-UP AND CONTRACT MANUFACTURING
AGREEMENT and a LICENSE AGREEMENT (collectively referred to as "the
Agreements"), both amended by the AMENDMENT TO THE FACILITY SET-UP AND CONTRACT
MANUFACTURING AGREEMENT AND THE LICENSE AGREEMENT (referred to as "Amendment
I") as well as Amendment II and Amendment III (referred to as such).

RMS desires that BEBIG provides some additional services to the customers of
RMS.

In light of the above, both parties desire to amend the existing Agreements
and the Amendments I, II, and III as follows:

1. GENERAL CUSTOMER SERVICES

BEBIG will provide service to the customers of RMS as set forth in Appendix I
"Customer Service Requirements" to this amendment excluding third party cost.
Both parties agree that for the services according to Appendix I RMS will pay
an annual fee of $95,000.00 plus taxes if any. The first annual fee will be
split into a payment of $48,000.00 due upon execution of this Amendment IV and
$47,000.00 due 6 months after the execution of this Amendment IV. The following
annual fees will be due in one payment annually after execution of this
Amendment IV.

RMS will reimburse BEBIG for third party costs involved with the customer
services (postage, phone cost etc.) above annually US$10,000.00 according to
actual cost plus a 30% handling charge plus taxes if any.

2. ADDITIONAL PHONE SERVICE

BEBIG will provide an operator phone service during BEBIG working hours (from
9:00 until 17:00 Central European Time). Additional operator phone service
outside of BEBIG working hours has to be provided by a call center outside of
BEBIG. If Radiance wishes such a service, it will reimburse BEBIG for all costs
involved with such a phone service at cost plus a 30% handling charge plus
taxes if any.
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BEBIG GmbH                         Amendment IV
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3. LICENSE FEE OFFSETS

Both parties agree, that amounts to be paid by RMS according to the provisions
of this Amendment IV are not subject to offsetting of the license fee or
royalties as provided by sec 4 LICENSE AGREEMENT.

4. MISCELLANEOUS

Except as specifically modified by this Amendment IV, all terms and conditions
of the Agreements and Amendment I, II, and III shall continue unchanged.

Date: 26 April 2001                             Date: 02 May, 2001

/s/ ANDRE HESS                                  /s/ JOSEPH A. BISHOP
---------------------------------               --------------------------------
    BEBIG GmbH                                      RMS

                                       2
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                   APPENDIX 1: CUSTOMER SERVICE REQUIREMENTS

ACCOUNTS RECEIVABLE

1.  Create a customer number for all new customers.

    a. Perform maintenance on a customer's account as requested by the customer
       or as directed by the appropriate Sales Manager or Controller of RMS, for
       all new and existing customers.

ORDER ENTRY

1.  Receive all purchase orders from the distributor and review against the
    distributor agreement to ensure that all contractual requirements are met.

2.  Create the Sales Order Form on the order entry system by entering the
    following critical information about the customer and the order.

    a. Assign the sales order reference number.

    b. Enter the customer number to get the billing and shipping addresses.

    c. Enter/Check the customers' purchase order number.

    d. Enter any special instructions given by the customer.

    e. Enter/Check the model numbers, quantities and the appropriate customer
       pricing per the agreement for the products being ordered.

3.  Create the Picking Sheet Form for the purpose of selecting the lot numbers
    against the products to be picked and shipped to the customer.

4.  BEBIG will take care of the order processing using the software package
    provided by Radiance.

BILLING PROCEDURE

    a. Mail original invoice to the customer.

    b. File and maintain a copy of the invoice with the sales and purchase
       order, along with any other written correspondence pertaining to the
       sales order in the Accounts Receivable File.

    c. File a copy of the invoice in the Numerical Invoice File.

    d. Mail the original freight bill to the customer and attach a copy to the
       Accounts Receivable copy of the invoice.
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OTHER CS/ DUTIES

      1. Answer routine questions and inquiries from the distributors and the
         sales managers regarding products, pricing and availability.

      2. Receive and process literature requests from distributors and others.

      3. Process and resolve any billing or related issues.

      4. Support RMS staff to generate on a weekly basis the 1 month rolling
         sales forecast.

      5. Review, coordinate, and process government tenders and letters of
         credit orders.

      6. Run and distribute the weekly sales reports and open order reports.

      7. Review inventory availability and coordinate orders.

      8. Perform month end closing of Accounts Receivable, Inventory, and Order
         Entry Run associated reports and file in the structure provided by RMS.

      9. Interface with Radiance Sales and Marketing personnel

     10. Administrative support for Radiance exhibit and training

                                       2[GRAPHIC OMITTED]

                          Global Home Marketing, Inc.

                                                          CUSIP NO.  37938H 10 1

                      AUTHORIZED STOCK: 50,000,000 SHARES
                           PAR VALUE: $.001 PER SHARE

THIS CERTIFIES THAT

IS THE RECORD HOLDER OF

     SHARES OF THE COMMON STOCK OF Global Home Marketing,  Inc.  transferable on
the  books of the  Corporation  in person or by duly  authorized  attorney  upon
surrender of this Certificate  properly endorsed.  This Certificate in not valid
until countersigned by the Transfer Agent and registered by the Registrar.

     Witness the facsimile seal of the Corporation and the facsimile  signatures
of its duly appointed officers.

                               [GRAPHIC OMITTED]
                                (Corporate Seal)

----------------                                                ----------------
   Secretary                                                       PresidentSUBSCRIPTION AGREEMENT

                                       AND

                       PROSPECTIVE PURCHASER QUESTIONNAIRE

                            GLOBAL HOME MARKETING, INC.

<PAGE>

                             SUBSCRIPTION AGREEMENT

TO: GLOBAL HOME STING, INC., "The Company", Seller

1. The undersigned hereby subscribes for the purchase of  ________________common
shares of  stock,  @$1.00  per  share,  of  Global  Home  Marketing,  Inc.  (the
"Company") in accordance with the terms and conditions of this Agreement.

2. This subscription is one of a limited number of such subscriptions for common
shares  of  stock  of the  Company.  The  execution  of  this  Agreement  of the
undersigned shall constitute an offer by the undersigned to subscribe for common
shares  of  stock  in the  amount  specified  below.  The  Seller,  Global  Home
Marketing,  Inc.,  shall have the right (in its sole  discretion) to reject such
offer for any reason whatsoever,  or, by executing a copy of this Agreement,  to
accept such offer. If such offer is accepted,  Global Home Marketing,  Inc. will
return an executed copy of this Agreement to the undersigned, along with a valid
share  certificate from the Company's  transfer agent,  National Stock Transfer,
Inc., 1512 South 1100 East, Salt Lake City, Utah 84105. If this  subscription is
rejected or if the offering is not consummated for any reason, the undersigned's
subscription  payment  will  be  returned,  uncashed,  as  soon  as  practicable
following  termination of the offering or the date of rejection,  as applicable.
It is understood that this subscription is not binding on Global Home Marketing,
Inc.  unless  and  until it is  accepted  by Global  Home  Marketing,  Inc.,  as
evidenced by its execution of this Subscription Agreement where indicated below.

 3.  The undersigned hereby makes the following representations and warranties:

     a. The undersigned  has been furnished with and has carefully  reviewed the
Memorandum and documents attached thereto.

     b. All information  provided to the Global Home Marketing,  Inc., including
that in the  Prospective  Purchaser  Questionnaire,  is  true  and  correct  and
complete in all respects as of the date hereof.

     c. The undersigned is at least  twenty-one (21) years of age and sufficient
legal capacity to execute this Agreement.

     d. The undersigned has sufficient knowledge and expertise in business,  and
financial matters to evaluate the merits and risk of an investment.

     e. The  undersigned  is an  accredited  investor as that term is defined in
Regulation D, adopted under the Securities Act of 1933, as amended.

     f. The undersigned  has analyzed and reviewed the information  contained in
the Summary Investment Memorandum and has had an opportunity to ask questions of
and receive  answers  from the Company,  or any person or persons  acting on its
behalf,  concerning  the terms and conditions of this  investment,  and all such
questions have been answered to the full satisfaction of the undersigned.

     g. The  undersigned  has adequate  means of providing for his current needs
and  possible  personal  contingencies  and has no need  for  liquidity  in this
investment,  and his overall  commitment  to  investments  which are not readily
marketable is not  disproportionate  to his net worth, and his investment in the
shares will not cause such overall commitment to become excessive.

<PAGE>

     h. The  undersigned  understands  that the common shares of stock have been
registered  under the Securities Act of 1933, as amended (the "Act") pursuant to
the completion of an SB-2 Registration Statement but not with any state.

     i. The  undersigned  is  acquiring  the common  shares of stock for his own
account for  investment  purposes only and is not  purchasing the subject shares
for an undisclosed third party.

     j. If the  undersigned  is a  corporation,  partnership,  trust,  or  other
entity, it represents:

          (i) It is duly organized, validly existing, and in good standing under
     the laws of the United States of America, or elsewhere,  and has all of the
     requisite power and authority to invest in the shares as provided herein.

          (ii) Such  investment does not result in any violation of, or conflict
     with,  any  term  of  the  charter  or  bylaws  of the  undersigned  or any
     instrument to which it is bound or any law or regulation applicable to it.

          (iii) Such  investment  has been duly  authorized by all the necessary
     action on behalf of the undersigned.

          (iv) This  Agreement has been duly executed and delivered on behalf of
     the undersigned and constitutes a legal, valid and binding agreement of the
     undersigned.

     The foregoing  representations and warranties shall be true and accurate as
of the date  hereof  and as of the date of  delivery  of the  purchase  price to
Global Home Marketing, Inc., and shall survive such delivery period.

4.     Miscellaneous

     a. This Agreement, any amendments or replacements hereof, and the legality,
validity,  and  performance  of the terms  hereof,  shall be  governed  by,  and
enforced,  determined and construed in accordance with, the laws of the State of
Nevada applicable to contracts, transactions and obligations entered into and to
be performed in such State.

     b. This Agreement  contains the entire agreement  between the parties.  The
provisions of this Agreement may not be modified or waived except in writing.

     c. This Agreement and the rights, powers and duties set forth herein shall,
except  as set  forth  herein,  bind and  inure  to the  benefit  of the  heirs,
executors, administrators, legal representatives, successors and assignes of the
parties hereto. The undersigned may not assign any of his rights or interests in
and under this  Agreement  wihout the prior  written  consent of the Global Home
Marketing, Inc., and any attempted assignment without such consent shall be void
and without effect.

     d. It is  understood  that this  Subscription  is offered on a subject  top
prior sale basis and is not binding on Global  Home  Marketing,  Inc.  until the
Company accepts it, which  acceptance is at the sole  discretion of Company,  by
executing this Subscription Agreement where indicated.

                                       -2-

<PAGE>

5.  Subscription.   The  undersigned  hereby  subscribes  for  the  purchase  of
______________common shares of stock of Global Home Marketing, Inc. and encloses
payment in the amount of $ ____________($1.00 per share) payable to "Global Home
Marketing, Inc., Special Account"

                       TYPE OF OWNERSHIP

                    _________ Individual

                    _________ Joint Tenants with Right of Survivorship

                    _________ Tenants in Common

                    _________ Community Property

                    _________ Other

Executed this _______ day of _________, 2001, at _______________________________

________________________________________________________________________________

______________________________________________
Print Name

______________________________________________
Signature of Investor

______________________________________________
Social Security or other identification number

If the Investor  has  indicated  that the shares will be held as joint  tenants,
tenants in common or as community property, please complete the following:

______________________________________________
Print Name of Spouse or Other Investor

______________________________________________
Signature of Spouse or Other Investor

______________________________________________
Social Security or other identification number

                                       -3-

<PAGE>

If the Investor is a partnership, corporation or trust, complete the following:

______________________________________________
Name of Partnership, Corporation or Trust
                                                 (affix seal, if any)

By:
   ___________________________________________

______________________________________________
Print Name of Individual Signing

______________________________________________
Capacity of Individual Signing

Accepted

Global Home Marketing, Inc.

By:
   ___________________________________________

Title:
      ________________________________________

______________________________________________
Date of Acceptance

                                      -4-
<PAGE>

                    PROSPECTIVE PURCHASER QUESTIONNAIRE

TO: GLOBAL HOME MARKETING, INC.

To Whom It May Concern:

The information  contained  herein is being furnished to you in order for you to
determine  whether the undersigned may purchase common shares of stock of Global
Home  Marketing,  Inc.,  pursuant to an SB-2  Registration  Statement,  from the
Company. The undersigned herein states that he (she) is a sophisticated investor
and has  knowledge  and  experience  in financial  and  business  matters and is
capable of evaluating the merits and risks of the proposed investment.

The undersigned further represents that (i) the information  contained herein is
complete  and  accurate  and may be relied upon by you and (ii) the  undersigned
will notify you  immediately of any material  change in any of such  information
occurring prior to the purchase of the subject common shares of stock.

The  undersigned  understands  and agrees that this  questionnaire  will be kept
strictly confidential.

In accordance with the foregoing, the following  representations and information
are hereby made and furnished by:

______________________________________________
Print Name of Prospective Purchaser

______________________________________________
Signature of Prospective Purchaser

                                        1

<PAGE>

  INSTRUCTIONS:      Please answer all questions. If the answer to any questions
                     is "None" or "Not Applicable," please so state.

 1 Full Name _______________________________________

    Social Security Number _________________________

    Age ________

    Occupation _____________________________________

    Citizenship___________________  Number of Dependents ___________

 Residential Address:

 ______________________________________________________

 ______________________________________________________

       Please indicate your preferred mailing address:

       (  ) Residential (  ) Business

2.   Was your  income  (from all  sources)  for each of the two latest  complete
     calendar years more than (check one):

   ______$ 30,000     _____$ 50.000     _____$100,000       _____$150,000
   ______$200.000     _____$250.000     _____$300,000       _____$350.000

     (a)  What percentage of your income as shown above was derived from sources
          other than salary?

          ___________________%

     (b)  Approximately  what  percentage of your income as shown above remained
          after payment of Federal,  state and local taxes, and after payment of
          all ordinary and necessary living expenses?

          ___________________%

    (c)   Does the above income represent your joint income with your spouse?

          Yes _______    No _______

3.   Is your  income from all  sources  anticipated  for the current tax year in
     excess of (check one):

   ______$ 30,000     _____$ 50.000     _____$100,000       _____$150,000
   ______$200.000     _____$250.000     _____$300,000       _____$350.000

     (a)  Does the above income represent your joint income with your spouse?

          Yes _______    No _______

                                        2

<PAGE>

4. Is your net worth as of the date hereof in excess of (check one):

   ______$ 30,000     _____$ 50.000     _____$100,000       _____$150,000
   ______$200.000     _____$250.000     _____$300,000       _____$350.000

     (a)  What  percentage  of your  net  worth as shown  above is  invested  in
          restricted  securities or investments in marketable securities (stock.
          bonds, debentures, or notes)?

        Restrictive securities   ______________%

        Marketable securities    ______________%

                                 ==============%

     (b)  Do these net worth  representations  include your spouse's  assets and
          liabilities?

          Yes _______    No _______

     (c)  What  percentage  of your net worth as shown above  constitutes  home,
          furnishings, and automobiles? _____________%

     (d)  What  percentage of your net worth as shown above  constitutes  liquid
          assets (cash or assets readily convertible to cash)? _____________%

5.   For investors other than natural persons:

     (a)  Type of entity.  Corporation _______ Trust _______ Partnership _______
          Other (specify) ___________________

     (b)  Date or organization: ____________________

     (c)  Number of equity owners (stockholders, partners, beneficiaries, etc.):

     (d)  Was the entity  formed for the primary  purpose of investing in direct
          participation programs or other passive investments?

          Yes _______    No _______

6.   Please supply the following information with respect to the bank (or banks)
     at which you maintain a regular checking account:

    Name of Bank:_____________________________

    Address:__________________________________

    Telephone:________________________________

    Contact:__________________________________

7.  (a) Are you  aware  that  the  securities  proposed  to be  offered  will be
        nonmarketable,  requiring  your  capital  investment  to be  maintained
       for  an indefinite period of time?

       Yes _______    No _______

                                        3

<PAGE>

     (b)  Do you have any  investments or contingent  liabilities  which you can
          reasonably   anticipate   could   cause  the  need  for  sudden   cash
          requirements in excess of cash readily available to you'.'

          Yes _______    No _______

          If "Yes," please explain.

          ______________________________________________________________________

          ______________________________________________________________________

          ______________________________________________________________________

8.   Please list your business or professional  educational  background (schools
     attended and degrees obtained):

     Schools                        Degree              Dates Attended

________________________________________________________________________________

________________________________________________________________________________

________________________________________________________________________________

9.   Please  list any  professional  licenses  or  registrations  including  bar
     admissions, accounting certifications,  real estate brokerage licenses, and
     SEC or state broker-dealer registrations, held by you:

________________________________________________________________________________

________________________________________________________________________________

________________________________________________________________________________

10.  Please list your principal  employment and business  activities  during the
     last five years, as well as any relevant financial experience.

     Employer                     Position/Title             Employment Dates

________________________________________________________________________________

________________________________________________________________________________

________________________________________________________________________________

11.  Please describe your experience as an investor, including amounts invested,
     in securities, particularly investments in nonmarketable securities.

________________________________________________________________________________

________________________________________________________________________________

________________________________________________________________________________

                                        4

<PAGE>

12.  Have you participated in other private placements of securities?

     Yes _______    No _______

I understand  that the Company will be relying on the accuracy and  completeness
of my responses to the  foregoing  questions  and I represent and warrant to the
Company as follows:

  i. The  answers  to the above  questions  are  complete  and cornea and may be
     relied upon by the Company in  determining  whether the offering in which I
     propose to participate is exempt from registration under the Securities Act
     of 1933, as amended;

  ii.I will  notify  the  Company  immediately  of any  material  change  in any
     statement made herein occurring prior to the closing of any purchase.

  iii. I, am an  "accredited  investor" as that term is defined in  Regulation D
     adopted under the Securities  Act of 1933, as amended and, have  sufficient
     knowledge and experience in financial and business  matters to evaluate the
     merits  and  risks of the  prospective  investments;  I am able to bear the
     economic risk of the investment and currently  could afford a complete loss
     of such investment

    IN WITNESS WHEREOF, I have executed this Prospective Purchaser Questionnaire
    this _____ day of____________

_______________________________            __________________________________
Prospective Purchaser                      Prospective Purchaser
Signature                                  Signature

_______________________________            __________________________________
Print Name                                 Print Name

Sworn to me this _____ day of _____________, 199

_______________________________
Notary Public

_______________________________
My commission expires:                            (Notarial Seal)

                                        5

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