Document:

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                                                                    Exhibit 4.03

                               AMENDMENT NO. 1 TO
                          REGISTRATION RIGHTS AGREEMENT

         This AMENDMENT NO. 1 TO REGISTRATION RIGHTS AGREEMENT dated January 25,
2001 (this "AMENDMENT") amends that certain Registration Rights Agreement, dated
as of June 30, 2000, by and among Neoforma.com, Inc., a Delaware corporation
(the "COMPANY"), and the Investors (the "PRIOR RIGHTS AGREEMENT"). The
capitalized terms not otherwise defined herein have the respective meanings
given to them in the Prior Rights Agreement.

                                    RECITALS

         WHEREAS, Section 7.1 of the Prior Rights Agreement states in part that
any term or provision of the Prior Rights Agreement may be amended by a writing
signed by the Company and the holders of a majority of the shares of the
Registrable Securities.

         WHEREAS, the undersigned parties include the Company and the holders of
a majority of the shares of the Registrable Securities.

         NOW, THEREFORE, in consideration of the mutual promises made herein and
other good and valuable consideration, the receipt and adequacy of which are
hereby acknowledged, the parties hereto agree to amend the Prior Rights
Agreement as follows:

         1. Amendment of Section 1.7 of the Prior Rights Agreement. Section 1.7
of the Prior Rights Agreement is amended to add (i) the shares of Common Stock
issued to VHA pursuant to that certain Common Stock Purchase Agreement, dated as
of January 25, 2001, by and between the Company and VHA and (ii) the shares of
Common Stock issued to UHC pursuant to that certain Common Stock Purchase
Agreement, dated as of January 25, 2001, by and between the Company and UHC to
the definition of Registrable Securities. Section 1.7 shall read in its entirety
as follows:

                  "1.7 "REGISTRABLE SECURITIES" means shares of Common Stock of
         the Company (i) issued or issuable upon conversion of the Preferred
         Stock (the "CONVERSION STOCK") and (ii) issued or issuable with respect
         to, or in exchange for or in replacement of the Conversion Stock or
         other Registrable Securities, (iii) issued or issuable with respect to,
         or in exchange for or in replacement of other securities convertible
         into or exercisable for Preferred Stock upon any stock split, stock
         dividend, recapitalization, or similar event, (iv) issued to the former
         stockholders of Pharos Technologies, Inc., (the "PHAROS INVESTORS") in
         connection with its acquisition by the Company, (v) issued to the
         former stockholders of U.S. LifeLine, Inc. (the "USL INVESTORS") in
         connection with its acquisition by the Company, (vi) issued to the
         former stockholders of EquipMD, Inc., (the "EMI INVESTORS") in
         connection with its acquisition by the Company, (vii) issued to, or
         issuable upon exercise of warrants issued to, VHA, Inc., a Delaware
         corporation ("VHA") or University Healthsystem Consortium, an Illinois
         corporation ("UHC") in connection with the commercial agreement among
         Neoforma, Novation, LLC, a Delaware limited liability company
         ("NOVATION"), Healthcare Purchasing Partners International, LLC, a
         Delaware limited liability company, VHA and UHC, (viii) issued
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         to VHA pursuant to that certain Common Stock Purchase Agreement, dated
         as of January 25, 2001, by and between the Company and VHA and (ix)
         issued to UHC pursuant to that certain Common Stock Purchase Agreement,
         dated as of January 25, 2001, by and between the Company and UHC (the
         shares of Common Stock of the Company (or other securities convertible
         or exchangeable therefor) described in clauses (vii), (viii) and (ix),
         the "NOVATION REGISTRABLE SECURITIES"), excluding: (A) any shares of
         Common Stock that have been sold to or through a broker, dealer, market
         maker or underwriter in a public distribution or a public securities
         transaction or redeemed by the Company in accordance with its
         Certificate of Incorporation, (B) any shares of Common Stock of the
         Company (or Preferred Stock or other securities convertible or
         exercisable therefor) that have been sold in violation of this
         Agreement, and (C) all shares of Common Stock of the Company (or
         Preferred Stock or other securities convertible or exchangeable
         therefor) described in clause (i), (ii), (iii), (iv), (v), (vi), (vii),
         (viii) or (ix) of this Section 1.7 held by a Holder that can, in the
         opinion of counsel to the Company, be sold by such Holder in a
         three-month period without registration under the Securities Act
         pursuant to Rule 144."

         2. All Other Terms Unchanged. Except as expressly modified by this
Amendment, all terms of the Prior Rights Agreement shall remain in full force
and effect.

         3. Governing Law. This Amendment shall be governed by and construed
under the internal laws of the State of Delaware as applied to agreements among
Delaware residents entered into and to be performed entirely within Delaware,
without reference to principles of conflict of laws or choice of laws.

         4. Counterparts. This Amendment may be executed in two or more
counterparts, each of which will be deemed an original, but all of which
together will constitute one and the same instrument.

         [THE REMAINDER OF THIS PAGE HAS BEEN INTENTIONALLY LEFT BLANK]
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                 IN WITNESS WHEREOF, this Amendment has been executed as of the
date first above written.

COMPANY:                                       INVESTORS (Entity):

NEOFORMA.COM, INC.

                                               ---------------------------------
                                                    (Printed Entity Name Here)

By: --------------------------------------
     Andrew L. Guggenhime                      By:
     Chief Financial Officer and Secretary        ------------------------------

                                               Name:
                                                    ----------------------------

                                               Title:
                                                    ----------------------------

                                               INVESTORS (Individual):

                                               ---------------------------------
                                               Signature Here

                                               ---------------------------------
                                               Printed Name Here

      [SIGNATURE PAGE TO AMENDMENT NO. 1 TO REGISTRATION RIGHTS AGREEMENT]<PAGE>   1

                                                                   EXHIBIT 10.17

                    FIRST AMENDMENT OF CO-BRANDING AGREEMENT

THIS FIRST AMENDMENT OF CO-BRANDING AGREEMENT (the "Amendment"), entered into as
of February 6, 2001 ("Amendment Effective Date"), is by and between VerticalNet
LLC, a Delaware limited liability company having a principal place of business
at 700 Dresher Road, Suite 100, Horsham, Pennsylvania 19044 ("VerticalNet") and
Neoforma.com, Inc., a Delaware corporation, having a principal place of business
at 3061 Zanker Road, San Jose, CA 95134 ("Neoforma").

                                    RECITALS

A.   WHEREAS, VerticalNet and Neoforma entered into a Co-Branding Agreement on
or about November 19, 1999 (the "Agreement").

B.   WHEREAS, pursuant to the Agreement, VerticalNet is to, inter alia, promote
Neoforma Shop, Neoforma Plan and Neoforma Auction within certain of
VerticalNet's vertical trade communities.

C.   WHEREAS, the Parties desire to amend the Agreement to change the operative
commercial terms and the Term of the Agreement.

THEREFORE, the Parties, intending to be legally bound, agree as follows:

1.   AMENDMENT

     1.1. Pursuant to Section 16.6 of the Agreement, Section 1.9 of the
Agreement shall be deleted in its entirety and replaced with the following
paragraph, which shall become part of the Agreement:

          1.9  INITIAL TERM shall mean the Effective Date through December 31,
          2000, unless earlier terminated pursuant to Section 11.

     1.2  Pursuant to Section 16.6 of the Agreement, Sections 10.2 of the
Agreement shall be deleted in its entirety and replaced with the following
paragraph, which shall become part of the Agreement:

          10.2 PROMOTIONAL FEES. In consideration of the performance by
          VerticalNet of its obligation to promote the Neoforma Shop, Neoforma
          Plan and Neoforma Auction under Section 8.2, Neoforma shall pay to
          VerticalNet a promotional fee equal to $750,000, payable in four equal
          quarterly and non-refundable installments of $187,500, with the first
          installment payable on the Effective Date, the second installment
          payable on the three month anniversary of the Effective Date, the
          third installment payable on the six month anniversary of the
          Effective Date, and the fourth and final installment payable on
          December 1, 2000.

     1.3  Pursuant to Section 16.6 of the Agreement, Section 11.1 of the
Agreement shall be deleted in its entirety.

2.   OTHER OBLIGATIONS, RIGHTS, REPRESENTATIONS AND WARRANTIES

     2.1  All other obligations, rights, representations and warranties set
forth in the Agreement remain unchanged and in full effect.
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     2.2  Each of VerticalNet and Neoforma agree that nothing set forth herein
will relieve either VerticalNet or Neoforma from those provisions of the
Agreement that by the provisions of the Agreement are to survive termination of
the Agreement and that each will comply with its obligations under Section 11.3
("Upon Termination") of the Agreement.

     2.3  Neither VerticalNet nor Neoforma shall publicly disclose the fact that
they have entered into this Amendment, or any of the terms, conditions or
provisions of this Amendment, except as may be required by any applicable law,
rule or regulation.

3.   GENERAL

     3.1  Capitalized Terms. All capitalized terms not defined herein shall have
the meaning ascribed to them in the Agreement.

     3.2  Titles. The headings appearing at the beginning of the sections
contained herein have been inserted for identification and reference purposes
only and shall not be used to determine the construction or interpretation of
this Amendment. The nomenclature of the defined terms used herein shall only be
used for the construction of this Amendment, and are not to be used for any
other purpose, including, but not limited to, interpretation for accounting
purposes.

     3.3  Counterparts. This Amendment may be executed in one or more
counterparts, each of which shall be deemed an original and all of which
together shall constitute one and the same instrument. This Amendment shall
become binding when any one or more counterparts hereof, individually or taken
together, bear the signatures of both Parties. For the purposes hereof, a
facsimile copy of this Amendment, including the signature pages hereto, shall be
deemed an original.

IN WITNESS WHEREOF, the parties have caused this Amendment to be executed by
their duly authorized representatives as of the dates set forth below.

VERTICALNET LLC                           NEOFORMA.COM, INC.

By: /s/ CHRISTOPHER G. KUHN               By: /s/ ANDREW GUGGENHIME
   -----------------------------------       -----------------------------------
Name: Christopher G. Kuhn                 Name: Andrew Guggenhime
     ---------------------------------         ---------------------------------
Title: VP, Legal Affairs                  Title: Chief Financial Officer
      --------------------------------          --------------------------------
Date: 2/7/01                              Date: 2/6/01
     ---------------------------------         ---------------------------------

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