Document:

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                                                                   Exhibit 10.15

As of August 24, 2006

Harbor Business Acquisition Corp.
200 Highpoint Drive, Suite 215
Chalfont, PA 18914-3922

H.C. Wainwright & Co., Inc.
52 Vanderbilt Avenue - 12th Floor
New York, NY  10017

RE:      INITIAL PUBLIC OFFERING

Gentlemen:

The undersigned security holder of Harbor Business Acquisition Corp.
("Company"), in consideration of H.C. Wainwright & Co., Inc. ("H.C. Wainwright")
entering into a letter of intent ("Letter of Intent") to underwrite an initial
public offering of the securities of the Company ("IPO") and embarking on the
IPO process, hereby agrees as follows (certain capitalized terms used herein are
defined in paragraph 13 hereof):

1. If the Company solicits approval of its stockholders of a Business
Combination, the undersigned will vote (i) all Insider Shares owned by it in
accordance with the majority of the votes cast by the holders of the IPO Shares,
(ii) all of the shares that may be acquired by it in the Private Placement, the
IPO or in the aftermarket for the Business Combination and (iii) all Insider
Shares and all shares that may be acquired by it in the Private Placement, the
IPO or in the aftermarket for an amendment to the Company's Certificate of
Incorporation to provide for perpetual existence of the Company in the event the
Business Combination is approved.

2. In the event that the Company fails to consummate a Business Combination
within twenty-four-month period immediately following the date of the prospectus
related to the IPO (such date being referred to herein as the "Termination
Date"), the undersigned shall (i) cause the Trust Fund (as defined in the Letter
of Intent) to be liquidated and distributed to the holders of IPO Shares and
(ii) take all reasonable actions within its power to cause the Company to
liquidate as soon as reasonably practicable pursuant to the requirements of the
Delaware General Corporation Law. The undersigned hereby waives any and all
right, title, interest or claim of any kind ("Claim") in or to any liquidating
distributions by the Company, including, without limitation, any distribution of
the Trust Fund (as defined in the Letter of Intent), as a result of such
liquidation with respect to its Insider Shares and the Private Placement Shares
and hereby waives any Claim the undersigned may have in the future as a result
of, or arising out of, any contracts or agreements with the Company and will not
seek recourse against the Trust Fund for any reason whatsoever.

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Harbor Business Acquisition Corp.
H.C. Wainwright & Co., Inc.                               As of August 24, 2006

3. [The undersigned acknowledges and agrees that the Company will not vote in
favor of consummation of any Business Combination which involves a company which
is affiliated with any of the Insiders unless the Company obtains an opinion
from an independent investment banking firm reasonably acceptable to H.C.
Wainwright that the Business Combination is fair to the Company's stockholders
from a financial perspective].

4. Except for monthly payments of $7,500 to be made to Harbor Business Group,
LLC for administrative payments neither the undersigned nor any affiliate of the
undersigned ("Affiliate") will be entitled to receive and will not accept any
compensation for services rendered to the Company prior to the consummation of
the Business Combination.

5. Neither the undersigned nor any Affiliate of the undersigned will be entitled
to receive or accept a finder's fee or any other compensation in the event the
undersigned or any Affiliate of the undersigned originates a Business
Combination.

6. The undersigned will escrow its Insider Shares for the three-year period
commencing on the Effective Date subject to the terms of a Stock Escrow
Agreement which the Company will enter into with the undersigned and an escrow
agent acceptable to the Company.

7. The undersigned represents and warrants that it:

                  (a) is not subject to or a respondent in any legal action for,
any injunction, cease-and-desist order or order or stipulation to desist or
refrain from any act or practice relating to the offering of securities in any
jurisdiction;
                  (b) has never been convicted of or pleaded guilty to any crime
(i) involving any fraud or (ii) relating to any financial transaction or
handling of funds of another person, or (iii) pertaining to any dealings in any
securities and he is not currently a defendant in any such criminal proceeding;
and

                  (c) has never been suspended or expelled from membership in
any securities or commodities exchange or association or had a securities or
commodities license or registration denied, suspended or revoked.

8. The undersigned has full right and power, without violating any agreement by
which it is bound, to enter into this letter agreement and to be a security
holder of the Company.

9. The undersigned hereby waives its right to exercise conversion rights with
respect to any shares of the Company's common stock owned or to be owned by the
undersigned, directly or indirectly, and agrees that it will not seek conversion
with respect to such shares in connection with any vote to approve a Business
Combination.

10. Other than in connection with a Business Combination, the undersigned hereby
agrees to not to vote in favor of an amendment to the Company's Certificate of
Incorporation to extend the Company's existence. Should such a proposal be put
before stockholders in connection with a Business Combination, the undersigned
hereby agrees to vote against such proposal. This paragraph may not be modified
or amended under any circumstances.

                                      -2-
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Harbor Business Acquisition Corp.
H.C. Wainwright & Co., Inc.                               As of August 24, 2006

11. The undersigned agrees not to sell any of its Insider Shares until the
Company's completion of a Business Combination.

12. The undersigned authorizes any financial institution or credit reporting
agency to release to H.C. Wainwright and its legal representatives or agents
(including any investigative search firm retained by H.C. Wainwright) any
information they may have about the undersigned's background and finances
("Information"). Neither H.C. Wainwright nor its agents shall be violating the
undersigned's right of privacy in any manner in requesting and obtaining the
Information and the undersigned hereby releases them from liability for any
damage whatsoever in that connection.

13. As used herein, (i) a "Business Combination" shall have the meaning set
forth in the form of Amended and Restated Certificate of Incorporation filed as
an exhibit to the registration statement filed in connection with the IPO; (ii)
"Insiders" shall mean all officers, directors and stockholders of the Company
immediately prior to the IPO; (iii) "Insider Shares" shall mean all of the
shares of Common Stock of the Company owned by an Insider prior to the IPO and
the Private Placement; (iv) "IPO Shares" shall mean the shares of Common Stock
issued in the Company's IPO; (v) "Private Placement Shares" shall mean the
shares of Common Stock underlying the 150,000 units issued in the Company's
private placement effected prior to the IPO; (vi) "Private Placement" shall mean
the Company's private placement effected prior to the IPO and (vii) "Convertible
Loans" shall mean the loans made by each of Harbor Healthcare Holding LLC and
Moreco Partners LLC in an aggregate amount of $800,000 ($920,000 if the
over-allotment option is exercised in full) as more fully described in the
prospectus for the IPO.

14. This letter agreement shall be governed by and construed and enforced in
accordance with the laws of the State of New York, without giving effect to
conflicts of law principles that would result in the application of the
substantive laws of another jurisdiction. The undersigned hereby agrees that any
action, proceeding or claim against the undersigned arising out of or relating
in any way to this Agreement shall be brought and enforced in the courts of the
State of New York or the United States District Court for the Southern District
of New York, and irrevocably submits to such jurisdiction, which jurisdiction
shall be exclusive. The undersigned hereby waives any objection to such
exclusive jurisdiction and that such courts represent an inconvenience forum.

                                  MORECO PARTNERS LLC

                                  By:  ______________________________
                                       Name:
                                       Title:

                                      -3-Exhibit 10.22

    
      

    

    Exhibit
      10.22

    

    CALCULATION
      OF US PRODUCT PROFIT SHARE FOR SCHEDULE II CLASSIFICATION

    

    During
      the first twenty-four (24) months following First Commercial Sale of the first
      Collaboration Product for ADHD, New River's share of US Product Profits pursuant
      to clause (b) of Section 7.4.1 shall be the greater of: (i) 25%, and (ii) the
      value of "X" determined as follows:

    

    X
      =
      {(0.25 * A) + [0.35 * (B - A)] + [0.1 * (B - 2A)]} / B

    

    A
      = the
      CII Threshold Sales for the applicable calendar year, as defined
      below

    

    B
      = the
      Net Sales of the applicable Collaboration Product in the US Territory during
      such calendar year

    

    After
      such twenty-four (24) month period, New River's share of US Product Profits
      pursuant to clause (b) of Section 7.4.1 shall be the greater of: (i) 50%, and
      (ii) the value of "Y" determined as follows:

    

    Y
      = {(0.5
      * A) + [0.6 * (B - A)] + [0.1 * (B - 2A)]} / B

    

    A
      = the
      CII Threshold Sales for the applicable calendar year, as defined
      below

    

    B
      = the
      Net Sales of the applicable Collaboration Product in the US Territory during
      such calendar year

    

    During
      all periods, Shire's share of US Product Profits will be equal to 100% minus
      New
      River's share of US Product Profits.

    

    By
      way of
      example, if the first Collaboration Product for ADHD receives Regulatory
      Approval in 2007, is classified as CII, and achieves U.S. sales of $312.5
      million in calendar year 2010, then New River's share of US Product Profit
      in
      that year would be (calculated in millions, for simplicity):

    

    X
      = {(0.5
      * 125) + [0.6 * (312.5 - 125)] + [0.1 * (312.5 - 2 * 125)]} / 312.5

    

    X
      = {62.5
      + 112.5 + 6.25} / 312.5

    

    X
      =
      0.58

    

    Thus,
      in
      this example, New River's share of US Product Profit for the first Collaboration
      Product for ADHD would be 58% and Shire's share would be 42%.

    

    For
      purposes of this Exhibit
      B,
      "CII
      Threshold Sales"
      means
      the following amount of Net Sales of a Collaboration Product in the US Territory
      during each of the following calendar years: 

    
      
        
        

      

      
        
        

        
          

        

      

      
        
        

      

    

     

    
      	
              Calendar
                Year

            	 	
              U.S.
                Sales

            
	 	 	 
	
              2007

            	 	
              $
                  32 million

            
	 	 	 
	
              2008

            	 	
              $  
                61 million

            
	 	 	 
	
              2009

            	 	
              $  
                95 million

            
	 	 	 
	
              2010

            	 	
              $
                125 million

            
	 	 	 
	
              2011

            	 	
              $
                155 million

            
	 	 	 
	
              2012

            	 	
              $
                200 million

            
	 	 	 
	
              and
                future years

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