Document:

Exhibit 10.1

 

AMENDMENT NO.
3 TO THE OPEN MARKET SALE AGREEMENTSM

 

March 4, 2021

 

JEFFERIES LLC

520 Madison Avenue

New York, New York 10022

 

Ladies and Gentlemen:

 

This
Amendment No. 3 to the Open Market Sale AgreementSM (this “Amendment”) is entered into as of the
date first written above by Arbutus Biopharma Corporation, a company incorporated under the laws of the Province of British Columbia
(the “Company”), and Jefferies LLC (“Agent”), that are parties to that certain Open Market
Sale AgreementSM, dated December 20, 2018 (the “Original Agreement”), as amended on December 20, 2019
and August 7, 2020. All capitalized terms not defined herein shall have the meanings ascribed to them in the Original Agreement.
The parties, intending to be legally bound, hereby amend the Original Agreement as follows:

 

1.            The
preamble to the Original Agreement is hereby deleted in its entirety and replaced with the following:

 

“Arbutus Biopharma
Corporation, a company incorporated under the laws of the Province of British Columbia (the “Company”), proposes,
subject to the terms and conditions stated herein, to issue and sell from time to time through Jefferies LLC, as sales agent and/or
principal (the “Agent”), the Company’s common shares, without par value per share (the “Common
Shares”), under one or more registration statements on Form S-3 filed with the Commission, on the terms set forth
in this agreement (this “Agreement”).”

 

2.            The
Company represents and warrants to, and agrees with the Agent that this Amendment has been duly authorized, executed and delivered
by, and is a valid and binding agreement of, the Company, enforceable in accordance with its terms, except as rights to indemnification
hereunder may be limited by applicable law and except as the enforcement hereof may be limited by bankruptcy, insolvency, reorganization,
moratorium or other similar laws relating to or affecting the rights and remedies of creditors or by general equitable principles.

 

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3.            This
Amendment together with the Original Agreement, as previously amended (including all schedules and exhibits attached hereto and
thereto and Placement Notices issued pursuant hereto and thereto), constitutes the entire agreement and supersedes all other prior
and contemporaneous agreements and undertakings, both written and oral, among the parties hereto with regard to the subject matter
hereof. Neither this Amendment nor any term hereof may be amended except pursuant to a written instrument executed by the Company
and the Agent. In the event that any one or more of the provisions contained herein, or the application thereof in any circumstance,
is held invalid, illegal or unenforceable as written by a court of competent jurisdiction, then such provision shall be given full
force and effect to the fullest possible extent that it is valid, legal and enforceable, and the remainder of the terms and provisions
herein shall be construed as if such invalid, illegal or unenforceable term or provision was not contained herein, but only to
the extent that giving effect to such provision and the remainder of the terms and provisions hereof shall be in accordance with
the intent of the parties as reflected in this Amendment. All references in the Original Agreement to the “Agreement”
shall mean the Original Agreement as amended by this Amendment; provided, however, that all references to “date of this Agreement”
in the Original Agreement shall continue to refer to the date of the Original Agreement.

 

4.            This
Amendment shall be governed by and construed in accordance with the internal laws of the State of New York applicable to agreements
made and to be performed in such state. Any legal suit, action or proceeding arising out of or based upon this Amendment or the
transactions contemplated hereby may be instituted in the federal courts of the United States of America located in the Borough
of Manhattan in the City of New York or the courts of the State of New York in each case located in the Borough of Manhattan in
the City of New York (collectively, the “Specified Courts”), and each party irrevocably submits to the exclusive
jurisdiction (except for proceedings instituted in regard to the enforcement of a judgment of any such court, as to which such
jurisdiction is non-exclusive) of such courts in any such suit, action or proceeding. Service of any process, summons, notice or
document by mail to such party’s address set forth above shall be effective service of process for any suit, action or other
proceeding brought in any such court. The parties irrevocably and unconditionally waive any objection to the laying of venue of
any suit, action or other proceeding in the Specified Courts and irrevocably and unconditionally waive and agree not to plead or
claim in any such court that any such suit, action or other proceeding brought in any such court has been brought in an inconvenient
forum. The provisions of this paragraph shall survive any termination of this Amendment.

 

5.            This
Amendment may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall
constitute one and the same instrument. Delivery of an executed amendment by one party to the other may be made by facsimile transmission
or electronic transmission (e.g., PDF).

 

[Remainder of Page Intentionally Blank]

 

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If the foregoing correctly
sets forth the understanding between the Company and the Agent, please so indicate in the space provided below for that purpose,
whereupon this letter shall constitute a binding amendment to the Original Agreement between the Company and the Agent.

 

	 	Very truly yours,
	 	 
	 	Jefferies LLC
	 	 
	 	By: 	/s/ Michael Magarro
	 	Name:	Michael Magarro
	 	Title:	Managing Director
	 	 
	 	ACCEPTED as of the date
	 	first-above written:
	 	 
	 	Arbutus Biopharma Corporation
	 	 
	 	By: 	/s/ William H. Collier
	 	Name: 	William H. Collier
	 	Title: 	President and Chief Executive OfficerEX-10.1

 Exhibit 10.1 

EXECUTION 
 AMENDMENT NO.
6 TO 
 MASTER REPURCHASE AGREEMENT 

Amendment No. 6 to Master Repurchase Agreement, dated as of March 1, 2021 (this “Amendment”), among CREDIT SUISSE
FIRST BOSTON MORTGAGE CAPITAL LLC (the “Administrative Agent”), CREDIT SUISSE AG, a company incorporated in Switzerland, acting through its Cayman Islands Branch (“CS Cayman” and a “Buyer”), ALPINE
SECURITIZATION LTD (“Alpine” and a “Buyer” and together with CS Cayman, the “Buyers”) and LOANDEPOT.COM, LLC (the “Seller”). 

RECITALS 
 The
Administrative Agent, CS Cayman and the Seller are parties to that certain (i) Master Repurchase Agreement, dated as of March 10, 2017 (as amended by Amendment No. 1, dated as of August 11, 2017, Amendment No. 2, dated as of
January 31, 2018, Amendment No. 3, dated as of April 8, 2019, Amendment No. 4, dated as of February 26, 2020 and Amendment No. 5, dated as of September 25, 2020, the “Existing Repurchase
Agreement”; and as further amended by this Amendment, the “Repurchase Agreement”) and (ii) Pricing Side Letter, dated as of March 10, 2017 (as amended, restated, supplemented or otherwise modified from time to
time, the “Pricing Side Letter”). Capitalized terms used but not otherwise defined herein shall have the meanings given to them in the Repurchase Agreement or Pricing Side Letter, as applicable. 

The Administrative Agent, the Buyers and the Seller have agreed, subject to the terms and conditions of this Amendment, that the Existing
Repurchase Agreement be amended to reflect certain agreed upon revisions to the terms of the Existing Repurchase Agreement. 
 Accordingly,
the Administrative Agent, the Buyers and the Seller hereby agree, in consideration of the mutual promises and mutual obligations set forth herein, that the Existing Repurchase Agreement is hereby amended as follows: 

SECTION 1. Definitions. Section 2 of the Existing Repurchase Agreement is hereby amended by adding the following definitions in
their proper alphabetical order: 
 “GNMA Haircut Amount” means, with respect to a Simultaneously Funded Early Buyout Loan,
an amount equal to (i) the amount due to GNMA to repurchase such Mortgage Loan from GNMA less (ii) the Purchase Price for such Mortgage Loan. 

“Simultaneously Funded Early Buyout Loan” means an Early Buyout which Seller intends to be repurchased from GNMA
substantially concurrently with the funding of the related Transaction hereunder. 
 SECTION 2. Program; Initiation of Transactions.
Section 3(d) of the Existing Repurchase Agreement is hereby amended by deleting such section in its entirety and replacing it with the following: 

d. With respect to a Simultaneously Funded Early Buyout Loan for which Seller has submitted a Transaction Request, provided that the GNMA
Haircut Amount has been 

 
remitted to the Administrative Agent, Administrative Agent shall remit the purchase price due to GNMA for such Simultaneously Funded Early Buyout Loan to the general payment clearing account of
Servicer. Within one (1) Business Day of such remittance, Seller shall cause Servicer to (i) segregate and remit such purchase price to the custodial account held for the Seller and (ii) report to GNMA that such Simultaneously Funded
Early Buyout Loan has been repurchased from GNMA. In the event that Servicer fails to repurchase such Simultaneously Funded Early Buyout Loan, Seller shall cause Servicer to remit the Purchase Price for such Simultaneously Funded Early Buyout Loan
to the account set forth in Section 9 within one (1) Business Day following the related Purchase Date. Notwithstanding the foregoing, when a Simultaneously Funded Early Buyout Loan is repurchased, the Purchase Date
hereunder shall be deemed the date of remittance of proceeds by Administrative Agent to Servicer. 
 SECTION 3. Conditions Precedent.
Section 10.b(3)(b) of the Existing Repurchase Agreement is hereby amended by deleting such section in its entirety and replacing it with the following: 

(b) If not a Wet-Ink Mortgage Loan, the Request for Certification and the related Asset Schedule
delivered by Seller, and (i) with respect to Mortgage Loans other than Simultaneously Funded Early Buyout Loans, the Trust Receipt and the Custodial Asset Schedule or (ii) with respect to Mortgage Loans that are Simultaneously Funded Early
Buyout Loans, a preliminary Custodial Asset Schedule, in each case, delivered by the Custodian. 
 SECTION 4. Conditions Precedent.
This Amendment shall become effective as of the date hereof (the “Amendment Effective Date”), subject to the satisfaction of the following conditions precedent: 

4.1 Delivered Documents. On the Amendment Effective Date, the Administrative Agent on behalf of Buyers shall have
received the following documents, each of which shall be satisfactory to the Administrative Agent in form and substance: 

(a) this Amendment, executed and delivered by the duly authorized officers of the Administrative Agent, Buyers, and the Seller;
and 
 (b) such other documents as the Administrative Agent or counsel to the Administrative Agent may reasonably request.

 SECTION 5. Representations and Warranties. The Seller hereby represents and warrants to the Administrative Agent and Buyers that
it is in compliance with all the terms and provisions set forth in the Repurchase Agreement on Seller’s part to be observed or performed, and that no Event of Default has occurred or is continuing, and Seller hereby confirms and reaffirms the
representations and warranties contained in Section 13 of the Repurchase Agreement as of the date hereof are true and correct in all material respects, except to the extent such representations relate to a date prior to the date hereof, in
which case the representations and warranties are true and correct in all material respects as of such date. 
 SECTION 6. Limited
Effect. Except as expressly amended and modified by this Amendment, the Existing Repurchase Agreement shall continue to be, and shall remain, in full force and effect in accordance with its terms. 

  
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 SECTION 7. Severability. Each provision and agreement herein shall be treated as
separate and independent from any other provision or agreement herein and shall be enforceable notwithstanding the unenforceability of any such other provision or agreement. 

SECTION 8. Counterparts. This Amendment may be executed by each of the parties hereto on any number of separate counterparts, each of
which shall be an original and all of which taken together shall constitute one and the same instrument. Delivery of an executed counterpart of a signature page of this Amendment in a Portable Document Format (PDF) or by facsimile shall be effective
as delivery of a manually executed original counterpart of this Amendment. The parties agree that this Amendment, any addendum or amendment hereto or any other document necessary for the consummation of the transactions contemplated by this
Amendment may be accepted, executed or agreed to through the use of an electronic signature in accordance with the E-Sign, UETA and any applicable state law. Any document accepted, executed or agreed to
in conformity with such laws will be binding on all parties hereto to the same extent as if it were physically executed and each party hereby consents to the use of any secure third party electronic signature capture service providers with
appropriate document access tracking, electronic signature tracking and document retention as may be approved by the Administrative Agent in its sole discretion. 

SECTION 9. GOVERNING LAW. THIS AMENDMENT SHALL BE GOVERNED BY, AND CONSTRUED IN ACCORDANCE WITH, THE LAWS OF THE STATE OF NEW
YORK WITHOUT REFERENCE TO THE CHOICE OF LAW PROVISIONS THEREOF. 
 [SIGNATURE PAGES FOLLOW] 

  
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 IN WITNESS WHEREOF, the parties have caused their names to be signed hereto by their
respective officers thereunto duly authorized as of the day and year first above written. 
  

			
	CREDIT SUISSE FIRST BOSTON MORTGAGE CAPITAL LLC, as Administrative Agent

 
			
		
	By:	 	  

 
			
	Name:
	Title:

 
			
	
	 CREDIT SUISSE AG, Cayman Islands

Branch, as a Buyer

 
			
		
	By:	 	  

	Name:
	Title:

 
			
		
	By:	 	  

	Name:
	Title:

 
			
	
	 ALPINE SECURITIZATION LTD, as a

Buyer, by Credit Suisse AG, New York Branch
 as Attorney-in-Fact

 
			
		
	By:	 	  

	Name:
	Title:

 
			
		
	By:	 	  

	Name:
	Title:

  
 Signature Page to
Amendment No. 6 to Master Repurchase Agreement 

 
			
	LOANDEPOT.COM, LLC, as Seller

 
			
		
	By:	 	 /s/ Patrick Flanagan

			
	Name: Patrick Flanagan
	Title: Chief Financial Officer

  
 Signature Page to
Amendment No. 6 to Master Repurchase Agreement

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