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                                                                    EXHIBIT 10.3

                               INDEMNITY AGREEMENT

      THIS AGREEMENT is made and entered into this 19th day of February 2004 by
and between INVISION TECHNOLOGIES, INC., a Delaware corporation (the
"Corporation"), and Andrew Siegel ("Agent").

                                    RECITALS

      WHEREAS, Agent performs a valuable service to the Corporation in his
capacity as Senior Vice President, Corporate Development of the Corporation;

      WHEREAS, the stockholders of the Corporation have adopted bylaws (the
"Bylaws") providing for the indemnification of the directors, officers,
employees and other agents of the Corporation, including persons serving at the
request of the Corporation in such capacities with other corporations or
enterprises, as authorized by the Delaware General Corporation Law, as amended
(the "Code");

      WHEREAS, the Bylaws and the Code, by their non-exclusive nature, permit
contracts between the Corporation and its agents, officers, employees and other
agents with respect to indemnification of such persons; and

      WHEREAS, in order to induce Agent to continue to serve as Senior Vice
President, Corporate Development of the Corporation, the Corporation has
determined and agreed to enter into this Agreement with Agent;

      NOW, THEREFORE, in consideration of Agent's continued service as Senior
Vice President, Corporate Development after the date hereof, the parties hereto
agree as follows:

                                    AGREEMENT

      1.    SERVICES TO THE CORPORATION. Agent will serve, at the will of the
Corporation or under separate contract, if any such contract exists, as Senior
Vice President, Corporate Development of the Corporation or as a director,
officer or other fiduciary of an affiliate of the Corporation (including any
employee benefit plan of the Corporation) faithfully and to the best of his
ability so long as he is duly elected and qualified in accordance with the
provisions of the Bylaws or other applicable charter documents of the
Corporation or such affiliate; provided, however, that Agent may at any time and
for any reason resign from such position (subject to any contractual obligation
that Agent may have assumed apart from this Agreement) and that the Corporation
or any affiliate shall have no obligation under this Agreement to continue Agent
in any such position.

      2.    INDEMNITY OF AGENT. The Corporation hereby agrees to hold harmless
and indemnify Agent to the fullest extent authorized or permitted by the
provisions of the Bylaws and the Code, as the same may be amended from time to
time (but, only to the extent that such amendment permits the Corporation to
provide broader indemnification rights than the Bylaws or the Code permitted
prior to adoption of such amendment).

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      3.    ADDITIONAL INDEMNITY. In addition to and not in limitation of the
indemnification otherwise provided for herein, and subject only to the
exclusions set forth in Section 4 hereof, the Corporation hereby further agrees
to hold harmless and indemnify Agent:

            (a)   against any and all expenses (including attorneys' fees),
witness fees, damages, judgments, fines and amounts paid in settlement and any
other amounts that Agent becomes legally obligated to pay because of any claim
or claims made against or by him in connection with any threatened, pending or
completed action, suit or proceeding, whether civil, criminal, arbitrational,
administrative or investigative (including an action by or in the right of the
Corporation) to which Agent is, was or at any time becomes a party, or is
threatened to be made a party, by reason of the fact that Agent is, was or at
any time becomes a director, officer, employee or other agent of Corporation, or
is or was serving or at any time serves at the request of the Corporation as a
director, officer, employee or other agent of another corporation, partnership,
joint venture, trust, employee benefit plan or other enterprise; and

            (b)   otherwise to the fullest extent as may be provided to Agent by
the Corporation under the non-exclusivity provisions of the Code and Section 41
of the Bylaws.

      4.    LIMITATIONS ON ADDITIONAL INDEMNITY. No indemnity pursuant to
Section 3 hereof shall be paid by the Corporation:

            (a)   on account of any claim against Agent solely for an accounting
of profits made from the purchase or sale by Agent of securities of the
Corporation pursuant to the provisions of Section 16(b) of the Securities
Exchange Act of 1934 and amendments thereto or similar provisions of any
federal, state or local statutory law;

            (b)   on account of Agent's conduct that is established by a final
judgment as knowingly fraudulent or deliberately dishonest or that constituted
willful misconduct;

            (c)   on account of Agent's conduct that is established by a final
judgment as constituting a breach of Agent's duty of loyalty to the Corporation
or resulting in any personal profit or advantage to which Agent was not legally
entitled;

            (d)   for which payment is actually made to Agent under a valid and
collectible insurance policy or under a valid and enforceable indemnity clause,
bylaw or agreement, except in respect of any excess beyond payment under such
insurance, clause, bylaw or agreement;

            (e)   if indemnification is not lawful (and, in this respect, both
the Corporation and Agent have been advised that the Securities and Exchange
Commission believes that indemnification for liabilities arising under the
federal securities laws is against public policy and is, therefore,
unenforceable and that claims for indemnification should be submitted to
appropriate courts for adjudication); or

            (f)   in connection with any proceeding (or part thereof) initiated
by Agent, or any proceeding by Agent against the Corporation or its directors,
officers, employees or other agents, unless (i) such indemnification is
expressly required to be made by law, (ii) the

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proceeding was authorized by the Board of Directors of the Corporation, (iii)
such indemnification is provided by the Corporation, in its sole discretion,
pursuant to the powers vested in the Corporation under the Code, or (iv) the
proceeding is initiated pursuant to Section 9 hereof.

      5.    CONTINUATION OF INDEMNITY. All agreements and obligations of the
Corporation contained herein shall continue during the period Agent is a
director, officer, employee or other agent of the Corporation (or is or was
serving at the request of the Corporation as a director, officer, employee or
other agent of another corporation, partnership, joint venture, trust, employee
benefit plan or other enterprise) and shall continue thereafter so long as Agent
shall be subject to any possible claim or threatened, pending or completed
action, suit or proceeding, whether civil, criminal, arbitrational,
administrative or investigative, by reason of the fact that Agent was serving in
the capacity referred to herein.

      6.    PARTIAL INDEMNIFICATION. Agent shall be entitled under this
Agreement to indemnification by the Corporation for a portion of the expenses
(including attorneys' fees), witness fees, damages, judgments, fines and amounts
paid in settlement and any other amounts that Agent becomes legally obligated to
pay in connection with any action, suit or proceeding referred to in Section 3
hereof even if not entitled hereunder to indemnification for the total amount
thereof, and the Corporation shall indemnify Agent for the portion thereof to
which Agent is entitled.

      7.    NOTIFICATION AND DEFENSE OF CLAIM. Not later than thirty (30) days
after receipt by Agent of notice of the commencement of any action, suit or
proceeding, Agent will, if a claim in respect thereof is to be made against the
Corporation under this Agreement, notify the Corporation of the commencement
thereof; but the omission so to notify the Corporation will not relieve it from
any liability which it may have to Agent otherwise than under this Agreement.
With respect to any such action, suit or proceeding as to which Agent notifies
the Corporation of the commencement thereof:

            (a)   the Corporation will be entitled to participate therein at its
own expense;

            (b)   except as otherwise provided below, the Corporation may, at
its option and jointly with any other indemnifying party similarly notified and
electing to assume such defense, assume the defense thereof, with counsel
reasonably satisfactory to Agent. After notice from the Corporation to Agent of
its election to assume the defense thereof, the Corporation will not be liable
to Agent under this Agreement for any legal or other expenses subsequently
incurred by Agent in connection with the defense thereof except for reasonable
costs of investigation or otherwise as provided below. Agent shall have the
right to employ separate counsel in such action, suit or proceeding but the fees
and expenses of such counsel incurred after notice from the Corporation of its
assumption of the defense thereof shall be at the expense of Agent unless (i)
the employment of counsel by Agent has been authorized by the Corporation, (ii)
Agent shall have reasonably concluded, and so notified the Corporation, that
there is an actual conflict of interest between the Corporation and Agent in the
conduct of the defense of such action or (iii) the Corporation shall not in fact
have employed counsel to assume the defense of such action, in each of which
cases the fees and expenses of Agent's separate counsel shall be at the

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expense of the Corporation. The Corporation shall not be entitled to assume the
defense of any action, suit or proceeding brought by or on behalf of the
Corporation or as to which Agent shall have made the conclusion provided for in
clause (ii) above; and

            (c)   the Corporation shall not be liable to indemnify Agent under
this Agreement for any amounts paid in settlement of any action or claim
effected without its written consent, which shall not be unreasonably withheld.
The Corporation shall be permitted to settle any action except that it shall not
settle any action or claim in any manner which would impose any penalty or
limitation on Agent without Agent's written consent, which may be given or
withheld in Agent's sole discretion.

      8.    EXPENSES. The Corporation shall advance, prior to the final
disposition of any proceeding, promptly following request therefor, all expenses
incurred by Agent in connection with such proceeding upon receipt of an
undertaking by or on behalf of Agent to repay said amounts if it shall be
determined ultimately that Agent is not entitled to be indemnified under the
provisions of this Agreement, the Bylaws, the Code or otherwise.

      9.    ENFORCEMENT. Any right to indemnification or advances granted by
this Agreement to Agent shall be enforceable by or on behalf of Agent in any
court of competent jurisdiction if (i) the claim for indemnification or advances
is denied, in whole or in part, or (ii) no disposition of such claim is made
within ninety (90) days of request therefor. Agent, in such enforcement action,
if successful in whole or in part, shall be entitled to be paid also the expense
of prosecuting his claim. It shall be a defense to any action for which a claim
for indemnification is made under Section 3 hereof (other than an action brought
to enforce a claim for expenses pursuant to Section 8 hereof, provided that the
required undertaking has been tendered to the Corporation) that Agent is not
entitled to indemnification because of the limitations set forth in Section 4
hereof. Neither the failure of the Corporation (including its Board of Directors
or its stockholders) to have made a determination prior to the commencement of
such enforcement action that indemnification of Agent is proper in the
circumstances, nor an actual determination by the Corporation (including its
Board of Directors or its stockholders) that such indemnification is improper
shall be a defense to the action or create a presumption that Agent is not
entitled to indemnification under this Agreement or otherwise.

      10.   SUBROGATION. In the event of payment under this Agreement, the
Corporation shall be subrogated to the extent of such payment to all of the
rights of recovery of Agent, who shall execute all documents required and shall
do all acts that may be necessary to secure such rights and to enable the
Corporation effectively to bring suit to enforce such rights.

      11.   NON-EXCLUSIVITY OF RIGHTS. The rights conferred on Agent by this
Agreement shall not be exclusive of any other right which Agent may have or
hereafter acquire under any statute, provision of the Corporation's Certificate
of Incorporation or Bylaws, agreement, vote of stockholders or directors, or
otherwise, both as to action in his official capacity and as to action in
another capacity while holding office.

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      12.   SURVIVAL OF RIGHTS.

            (a)   The rights conferred on Agent by this Agreement shall continue
after Agent has ceased to be a director, officer, employee or other agent of the
Corporation or to serve at the request of the Corporation as a director,
officer, employee or other agent of another corporation, partnership, joint
venture, trust, employee benefit plan or other enterprise and shall inure to the
benefit of Agent's heirs, executors and administrators.

            (b)   The Corporation shall require any successor (whether direct or
indirect, by purchase, merger, consolidation or otherwise) to all or
substantially all of the business or assets of the Corporation, expressly to
assume and agree to perform this Agreement in the same manner and to the same
extent that the Corporation would be required to perform if no such succession
had taken place.

      13.   SEPARABILITY. Each of the provisions of this Agreement is a separate
and distinct agreement and independent of the others, so that if any provision
hereof shall be held to be invalid for any reason, such invalidity or
unenforceability shall not affect the validity or enforceability of the other
provisions hereof. Furthermore, if this Agreement shall be invalidated in its
entirety on any ground, then the Corporation shall nevertheless indemnify Agent
to the fullest extent provided by the Bylaws, the Code or any other applicable
law.

      14.   GOVERNING LAW. This Agreement shall be interpreted and enforced in
accordance with the laws of the State of Delaware.

      15.   AMENDMENT AND TERMINATION. No amendment, modification, termination
or cancellation of this Agreement shall be effective unless in writing signed by
both parties hereto.

      16.   IDENTICAL COUNTERPARTS. This Agreement may be executed in one or
more counterparts, each of which shall for all purposes be deemed to be an
original but all of which together shall constitute but one and the same
Agreement. Only one such counterpart need be produced to evidence the existence
of this Agreement.

      17.   HEADINGS. The headings of the sections of this Agreement are
inserted for convenience only and shall not be deemed to constitute part of this
Agreement or to affect the construction hereof.

      18.   NOTICES. All notices, requests, demands and other communications
hereunder shall be in writing and shall be deemed to have been duly given (i)
upon delivery if delivered by hand to the party to whom such communication was
directed or (ii) upon the third business day after the date on which such
communication was mailed if mailed by certified or registered mail with postage
prepaid:

            (a)   If to Agent, at the address indicated on the signature page
hereof.

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            (b)   If to the Corporation, to:

                  INVISION TECHNOLOGIES, INC.
                  7151 Gateway Blvd.
                  Newark, CA  94560

or to such other address as may have been furnished to Agent by the Corporation.

         IN WITNESS WHEREOF, the parties hereto have executed this Agreement on
and as of the day and year first above written.

                               INVISION TECHNOLOGIES, INC.

                               By: /s/ Sergio Magistri
                                   ---------------------------------------------
                                      Name: Sergio Magistri
                                      Title: President & Chief Executive Officer

                               AGENT

                                /s/ Andrew D. Siegel
                               -------------------------------------------------
                               Name: Andrew Siegel

                               Address:

                               901 Cotton Street
                               Menlo Park, CA 94025

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

                                                                   EXHIBIT 10.17

                       LICENSE AND COLLABORATION AGREEMENT

      THIS LICENSE and COLLABORATION AGREEMENT (together with the exhibits
attached hereto which are hereby incorporated by reference, the "Agreement") is
made and entered into as of the 28th day of January 2004 (the "Effective Date")
by and between Genelabs Technologies, Inc., a California corporation having its
principal place of business at 505 Penobscot Drive, Redwood City, California,
United States 94063 ("Genelabs"), and Tanabe Seiyaku Co., Ltd., a Japanese
corporation having its principal office at 2-10 Dosho-machi 3-chome, Chuo-ku,
Osaka, Japan ("Tanabe").

                                    RECITALS

      WHEREAS, Genelabs is a pharmaceutical company engaged in the research,
development and commercialization of drugs, including a proprietary product
containing dehydroepiandrosterone, also known as prasterone, which is currently
being developed in the United States ("U.S.") and Europe for systemic lupus
erythematosus ("SLE");

      WHEREAS, Tanabe is a pharmaceutical company interested in entering into a
business relationship with Genelabs for the development, registration and
commercialization of Tanabe Products (as hereinafter defined) in Japan;

      WHEREAS, Tanabe desires to develop and commercialize Tanabe Products (as
such term is hereinafter defined) in Japan under the terms and conditions set
forth in this Agreement;

      WHEREAS, Tanabe desires to obtain, and Genelabs is willing to grant to
Tanabe, an exclusive license to certain Genelabs patents and Prasterone-related
know-how to develop, register and commercialize Tanabe Products in Japan, on the
terms and conditions provided in this Agreement; and

      WHEREAS, Tanabe desires to purchase through Genelabs, and Genelabs is
willing to arrange for the supply to Tanabe of, API (as hereinafter defined)
and, if applicable, Tanabe Products (as hereinafter defined) to Tanabe for use
in developing, registering and commercializing Tanabe Products in Japan in
accordance with this Agreement.

      NOW, THEREFORE, in consideration of the foregoing and the covenants and
promises contained in this Agreement, the parties hereby agree as follows:

                                    AGREEMENT

1.    DEFINITIONS

As used herein, the following terms shall have the following meanings:

            1.1   "AFFILIATE" means any entity that, directly or indirectly,
through one or more intermediates, is (and for so long as it is) controlled by,
controls, or is under common control with Tanabe or Genelabs, as the case may
be, as of or after the Effective Date. For purposes of this definition only, the
term "control" means the possession of the power to direct or cause the
direction of the management and policies of an entity, whether by ownership of
voting stock or partnership interest, by contract or otherwise, including direct
or indirect ownership of more than fifty percent (50%) of the voting interest in
the entity in question; provided, however, that if local law requires a minimum
percentage of local ownership, control will be established by direct or indirect
beneficial ownership of one hundred percent (100%) of the maximum ownership
percentage that may, under such local law, be owned by foreign interests.

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

            1.2   "API" shall mean the bulk active pharmaceutical ingredient
Prasterone.

            1.3   "APPLICABLE LAWS" means all applicable laws, rules,
regulations and guidelines within or without the Territory that may apply to the
development, marketing or sale of Tanabe Products in the Territory or the
performance of either party's obligations under this Agreement including without
limitation laws, regulations and guidelines governing the import, export,
development, manufacture, marketing, distribution and sale of Tanabe Products in
the Territory, to the extent applicable and relevant, and including all Current
Good Manufacturing Practices (and applicable ICH rules and guidelines, such as
the International Conference on Harmonization Guidelines, Good Manufacturing
Practice Guidance for Active Pharmaceutical Ingredients), current Good Clinical
Practices standards, guidelines promulgated by the FDA and the Competent
Authorities, including trade association guidelines, where applicable, as well
as U.S. export control laws.

            1.4   "COGS" means the total amount charged to Genelabs by Genelabs'
Third Party manufacturer for API and/or Prasterone Product supplied by Genelabs
to or for Tanabe pursuant to Article 7, together with any delivery, freight,
handling, testing, storage, taxes, tariffs, duties and insurance related
expenses if incurred by or charged to Genelabs in connection with such supply.

            1.5   "COMPETENT AUTHORITIES" means collectively the entities
responsible for the regulation of medicinal products intended for human use in
Japan, including the Pharmaceutical and Medical Safety Bureau within the
Japanese Ministry of Health, Labour and Welfare ("MHLW").

            1.6   "CURRENT GOOD MANUFACTURING PRACTICES" or "CGMP" means the
applicable regulations set forth in 21 C.F.R. Subchapter C (Drugs) and
Subchapter H (Medical Devices), including Parts 210-211, 312, 808, 812 and 820,
and the requirements thereunder imposed by the FDA, and the equivalent
regulations and requirements in jurisdictions outside the U.S.

            1.7   "FDA" means the U.S. Food and Drug Administration, or any
successor thereto, having the administrative authority to regulate the marketing
of human pharmaceutical products or biological therapeutic products, delivery
systems and devices in the U.S.

            1.8   "FIELD" means the treatment and/or prevention of disease,
disorders or other conditions in humans.

            1.9   "GENELABS CLINICAL DATA" means any Results, owned, generated,
developed, created or originated in connection with (a) pre-clinical or clinical
trials or testing of Prasterone Products or (b) other development efforts with
respect to Prasterone Products, by Genelabs and/or its Affiliates (including by
employees, consultants and Third Party contractors working on behalf of Genelabs
or its Affiliates) and/or Genelabs Licensees and/or Third Party licensors, to
the extent Genelabs has the right under its agreements with such licensees
and/or licensors to provide or to sublicense such Results to Tanabe and solely
in accordance with Sections 2.4 and/or 2.5 hereunder.

            1.10  "GENELABS IMPROVEMENTS" means all Improvements invented,
owned, developed, created or conceived by Genelabs and/or its Affiliates
(including by employees, consultants or Third Party contractors (excluding
manufacturers) working on behalf of Genelabs or its Affiliates) and/or Genelabs
Licensees and/or Third Party licensors, to the extent Genelabs has the right
under its agreements with such licensees and/or such Third Party licensors to
provide or to sublicense such Improvements to Tanabe and solely in accordance
with Section 2.6 hereunder.

License and Collaboration Agreement (Prasterone)

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

            1.11  "GENELABS IMPROVEMENT PATENTS" means those Patents covering or
claiming Genelabs Improvements, or the manufacture or use thereof.

            1.12  "GENELABS KNOW-HOW" means all intellectual property and
proprietary rights, excluding any trademark rights and patent rights (but
including, without limitation, all trade secret, know-how, and copyright
rights), in, to and under Technology that is (a) invented, developed, created or
conceived by Genelabs, its Affiliates and/or Genelabs Licensees (including by
employees, consultants or Third Party contractors (excluding manufacturers)
working on behalf of Genelabs, its Affiliates and/or Genelabs Licensees) and/or
Third Party licensors, (b) owned by Genelabs, its Affiliates and/or Genelabs
Licensees and/or Third Party licensors, (c) useful or necessary for the
manufacture, use or sale of Tanabe Products in the Field in the Territory and
(d) solely to the extent that Genelabs has the right under its agreements with
Genelabs Licensees and/or Third Party licensors to license such rights to Tanabe
hereunder. Genelabs Know-How shall not include Genelabs Improvements or Genelabs
Clinical Data.

            1.13. "GENELABS LICENSEES" has the meaning set forth in Section 5.4.

            1.14  "GENELABS PATENTS" means Patents listed in Exhibit A together
with any patents issued thereon or claiming priority back thereto. Genelabs
Patents shall not include Genelabs Improvement Patents or Genelabs Clinical
Data.

            1.15  "GOOD LABORATORY PRACTICES" or "GLP" means the regulations set
forth in 21 C.F.R. Part 58 and the requirements thereunder imposed by the FDA,
and the equivalent thereof in jurisdictions outside the U.S..

            1.16  "IMPROVEMENT" means any information, discoveries, processes,
procedures, devices, compositions of matter, know-how, trade secrets, designs,
formulae, specifications, methods, techniques, technical information, concepts,
developments or inventions which is useful or necessary to the manufacture, use
or sale of Prasterone Products and which is invented, generated, or otherwise
acquired on or after the Effective Date.

            1.17  "JOINT PATENT(S)" means any Patent claiming a Joint Invention
(as such term is defined in Section 9.1(a)); provided however that Joint Patents
shall not include patents covering Genelabs Improvements or Tanabe Improvements.

            1.18  "NDA" means a new drug application and any related
registrations or notifications to the FDA, or any comparable application in
Japan and related registrations or notifications.

            1.19  "NET SALES" means the amount billed or billable by Tanabe, its
Affiliates and/or Tanabe Sublicensees for sales, transfers or other dispositions
of Tanabe Products to Third Parties, less the following deductions or
allowances: (a) transportation and freight charges relating to Tanabe Product,
including handling and insurance relating thereto allocated in accordance to
Generally Accepted Accounting Principles in Japan but applied consistently with
their application to sales and other dispositions of other Tanabe products; (b)
sales taxes, exercise taxes, and other taxes (but excluding all income taxes)
and duties paid by Tanabe, its Affiliate or sublicensees in relation to Tanabe
Product imposed upon the importation, use or sale of such Tanabe Product; (c)
customary trade, quantity and cash discounts allowed and actually taken on
Tanabe Product; (d) credit for returns, refunds, rebates and allowance, or
trades to customers for returned or recalled Tanabe Product; (e) chargebacks for
uncollectible accounts provided however that any deduction or allowance taken by
Tanabe in any Tanabe fiscal year for such chargebacks shall not exceed one
percent (1%) of Net Sales for such fiscal year, and (f) customary product
rebates and product charge backs allowed and actually taken including those

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

granted to the wholesalers in the Territory. Tanabe Products provided free of
charge for compassionate use or other charitable purposes, the value of such
supply (based on the price to wholesalers) not to exceed one percent (1%) of Net
Sales in the Tanabe fiscal year of such supply, and transfers between Tanabe and
Tanabe Sublicensees (provided that such Sublicensees are not the end users of
Tanabe Products) shall not be included in the computation of Net Sales
hereunder.

            1.20  "PATENT(S)" means patents, inventors' certificates and patent
applications, together with any renewal, division, continuation, continued
prosecution application or continuation-in-part of any of such patents,
certificates and applications, any and all patents or certificates of invention
issuing thereon, and any and all reissues, reexaminations, extensions,
divisions, renewals of or to any of the foregoing, and any foreign counterparts
of any of the foregoing.

            1.21  "PRASTERONE" means dehydroepiandrosterone, including all
synthetic and natural forms thereof.

            1.22  "PRASTERONE PRODUCT" means any pharmaceutical product in which
Prasterone, including dehydroepiandrosterone Polymorph I and all synthetic and
natural forms thereof, is an active pharmaceutical ingredient, alone or together
with any other ingredient or component.

            1.23. "PRODUCT DEVELOPMENT PLAN" means the development plans
outlining the activities to be conducted by or for Tanabe to develop and obtain
Regulatory Approvals for Tanabe Products as set forth in Article 2, as amended
from time to time in accordance with Section 2.3.

            1.24  "REGULATORY APPROVAL" means approval by the Competent
Authorities having jurisdiction over a single application or set of applications
comparable to an NDA and satisfaction of any related applicable regulatory and
notification requirements, if any, together with any other approval necessary to
make (if applicable) and sell pharmaceuticals commercially in Japan.

            1.25  "RESULTS" means any research, pre-clinical, clinical,
development, post-marketing studies or other testing results, data or related
information or technology generated, developed, created or originated prior to
or during the term of this Agreement relating to Prasterone Products.

            1.26  "SLE" shall have the meaning given thereto in the first
"whereas" clause of this Agreement.

            1.27  "TANABE CLINICAL DATA" means any Results owned, generated,
developed, created or originated in connection with (a) pre-clinical or clinical
trials or testing of Prasterone Products or (b) other development efforts with
respect to Prasterone Products, by Tanabe, its Affiliates, and/or Tanabe
Sublicensees (including employees, consultants and Third Party contractors
working on behalf of Tanabe, its Affiliates and/or Tanabe Sublicensees) and/or
Third Party licensors, to the extent Tanabe has the right under its agreements
with its Third Party licensors to provide or to sublicense such Results to
Genelabs and solely in accordance with Section 2.5 hereunder.

            1.28  "TANABE IMPROVEMENTS" means all Improvements which are owned,
invented, developed, created or conceived by Tanabe, its Affiliates and/or
Tanabe Sublicensees (including by employees, consultants or other Third Party
contractors working on behalf of Tanabe, its Affiliates and/or Tanabe
Sublicensees) and/or Third Party licensors, to the extent Tanabe has the right
under its agreements with its Third Party licensors to provide or to sublicense
such Improvements to Genelabs and solely in accordance with Section 2.6
hereunder.

License and Collaboration Agreement (Prasterone)

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

            1.29  "TANABE IMPROVEMENT PATENTS" means those Patents covering or
claiming Tanabe Improvements, or the manufacture or use thereof.

            1.30  "TANABE PRODUCT(S)" means a Prasterone Product developed under
this Agreement by or for Tanabe.

            1.31  "TANABE SUBLICENSEE(S)" means any Third Party to whom Tanabe
has granted a sublicense under all or any part of the rights granted to it by
Genelabs under this Agreement in accordance with Section 3.2.

            1.32  "TECHNOLOGY" means, to the extent related to Prasterone, any
technical information; ideas; discoveries; knowledge; know-how; skill;
experience; concepts; data; processes; procedures; methods; techniques;
protocols; formulae; trade secrets; inventions (whether or not patentable);
media; research tools; compositions; software; hardware; instruments; documents;
works of authorship; formulations; and other physical, chemical or biological
materials and information, including, without limitation, clinical and
regulatory strategies; test data (including pharmacological, toxicological and
clinical test data), analytical and quality control data, manufacturing, patent,
marketing and legal data or descriptions; apparatus; devices; chemical
formulations; compound compositions of matter; product samples; assays and
similar information and inventions.

            1.33  "TERRITORY" means Japan.

            1.34  "THIRD PARTY" means any person or entity other than Tanabe or
Genelabs or an Affiliate of Tanabe or Genelabs.

            1.35  "VALID CLAIM" means (a) any claim of an issued and unexpired
Patent which has not been held unenforceable or invalid by a court or other
governmental agency of competent jurisdiction in an unappealed or unappealable
decision, and which has not been disclaimed or admitted to be invalid or
unenforceable through reissue or otherwise, or (b) a pending claim in a pending
patent application. Notwithstanding Section 1.35(b) above, in the event that a
pending claim in a pending patent application does not issue as a valid and
enforceable claim in an issued patent within five (5) years after the earliest
priority date of such patent application, such a pending claim shall not be a
Valid Claim, unless and until such pending claim subsequently issues as a claim
in an issued patent, in which case such claim shall be reinstated and be deemed
to be a Valid Claim as of the date of issuance of such patent provided that it
otherwise falls within the definition of this Section 1.35(a).

2.    DEVELOPMENT PROGRAM.

            2.1   DEVELOPMENT AND COMMERCIALIZATION OF TANABE PRODUCT. Tanabe
shall (a) use its commercially reasonable effort in conducting the development
(including the filing and obtaining of Regulatory Approvals) and
commercialization of Tanabe Products in the Territory, and (b) conduct such
efforts in accordance with the Product Development Plan, the Commercialization
Plan (as defined in Section 5.2), this Agreement and all Applicable Laws
applicable to the development, registration, manufacture, use, sale, offer for
sale, and importation of Tanabe Products by or on behalf of Tanabe. Tanabe shall
exercise commercially reasonable diligent efforts to develop, obtain Regulatory
Approval of and commercialize Tanabe Products in the Territory.

            2.2   JOINT STEERING COMMITTEE. Promptly after the Effective Date,
the parties will form a Joint Steering Committee ("JSC"). The JSC will oversee,
at a strategic level, the development and commercialization of Tanabe Products
as contemplated by this Agreement by coordinating the

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development and commercialization efforts of Tanabe in the Territory with the
goal of maximizing sales of Tanabe Products. Accordingly, in addition to the
specific matters addressed elsewhere in this Agreement, and subject to the other
provisions of this Agreement, the JSC shall oversee all Tanabe Product related
activities in the Territory and shall (i) determine the specific goals for the
development of Tanabe Products and the priorities thereof, (ii) monitor the
progress and results of the development process, (iii) review the objectives and
strategies of Tanabe's commercialization plans and other commercialization
information provided by Tanabe, (iv) monitor Tanabe's progress towards such
goals and objectives, (v) facilitating communication and information sharing
between the parties with respect to development and commercialization of Tanabe
Products, and (vi) undertake, review and approve such other matters as are
provided for the JSC under this Agreement or as may be mutually agreed by the
parties.

                  (a)   COMPOSITION, ETC. The JSC shall consist of two (2)
senior members from each party with appropriate authority. The composition of
the JSC may change based on the stage of the development and commercialization
of Tanabe Products. Each party will provide reasonable written notice to the
other party of any change in its representatives on the JSC. In addition to
generally overseeing Tanabe Product development and commercialization,
facilitating communication and information sharing between the parties and
managing Joint Inventions and Joint Patents, the JSC shall approve and oversee
Tanabe's Tanabe Product development strategies, development timelines, marketing
plans and annual sales forecast for the Territory.

                  (b)   MEETINGS. The JSC will meet at least every six (6)
months or at least two (2) times per year either in person or through
tele/video-conference. If in person, meeting location will generally alternate
between Tanabe's facility in Osaka, Japan and Genelabs' facility in Redwood
City, California unless otherwise agreed by the parties. The host of each
meeting will serve as chair thereof. In addition, teleconference meetings may be
held on a regular basis, as needed, to discuss data and progress of Tanabe
Products. The JSC will keep meeting minutes and prepare a written semi-annual
progress report for respective internal senior management review. Each party
shall bear all of its own travel, lodging, meals and other costs and expenses
properly allocable to the participation of its representatives on the JSC.

                  (c)   DISPUTES. The JSC shall resolve all issues by consensus
(i.e., by unanimous vote of all four (4) members). In the event that the JSC is
unable to resolve any disputes with respect to issues or matters under its
consideration, the JSC shall refer such dispute to the chairman of the board,
President, or the Chief Executive Officer of each party in writing, reasonably
describing such dispute and the respective positions of the parties. The party
executives shall meet in person or by video-conference within thirty (30) days
after receiving such notice. If such executive mediation is unable to resolve
such dispute, Tanabe shall have the deciding vote; provided however that Tanabe
shall not have the deciding vote where the dispute involves the filing,
prosecution, maintenance, enforcement and/or defense of Joint Patent or
treatment of Joint Inventions, in which case, the parties shall invoke a neutral
decision making process involving neutral third parties (e.g. arbitration) for
final resolution in accordance with the provisions set forth in Section 17.1.
For the avoidance of doubt, the JSC shall have no authority over determinations
concerning whether a party has complied with the terms and conditions of this
Agreement, including without limitation, disputes relating to the triggering and
payment of milestones under Section 6.2.

            2.3   PRODUCT DEVELOPMENT PLAN. Within six (6) months after the
Effective Date, Tanabe shall submit to the JSC a proposed Product Development
Plan, which is reasonably designed to successfully develop and obtain Regulatory
Approval for Tanabe Products for SLE indications. For clarity, the decision on
which subcategory of the SLE indications (e.g. steroid reduction or prevention
of bone mineral density ("BMD") loss) to be pursued shall be determined by
Tanabe. The JSC shall review

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and approve the Product Development Plan and any and all amendments thereto.
Tanabe shall, at its own cost and expense, conduct the development and
regulatory activities specified in, and in accordance with, the Product
Development Plan to obtain the Regulatory Approval of Tanabe Products in the
Territory. Tanabe shall also provide quarterly written updates summarizing its
progress under the Product Development Plan in reasonable detail for the JSC's
review.

            2.4   SHARING OF RESULTS AND TECHNOLOGY

                  (a)   Genelabs shall provide Tanabe a copy of its existing
electronic version of NDA No. 21-239 and EMEA/H/C/531, which electronic version
may not include the full NDA filing in its entirety, and an index thereto, also
in electronic form, upon the Effective Date. Thereafter, during the term of the
Agreement, in addition to sharing of information at JSC meetings, (i) Genelabs
shall share with Tanabe Genelabs Improvements, Genelabs Know-How and Genelabs
Clinical Data obtained by or for Genelabs after the Effective Date, to the
extent necessary or useful for Tanabe to develop, manufacture, use or sell
Tanabe Products in the Territory, including the preparation of regulatory
filings or fulfillment of regulatory obligations related to Tanabe Products and
(ii) Tanabe shall share with Genelabs know-how within the Tanabe Improvements
and Tanabe Clinical Data obtained by or for Tanabe, to the extent necessary or
useful for Genelabs to develop, manufacture, use or sell Prasterone Products
outside the Territory. Notwithstanding anything herein to the contrary,
disclosure by Genelabs to a Genelabs Licensee of such know-how of Tanabe and
Tanabe Clinical Data for use by such licensee shall be limited by Genelabs, on a
case by case basis, to the same extent that such Genelabs Licensee limits the
disclosure to and use by Tanabe of such licensee's Results or Improvements under
such licensee's agreement with Genelabs. For portions of NDA No. 21-239 and
EMEA/H/C/531 not made available to Tanabe in electronic format and/or underlying
information which is referred to or summarized in such regulatory filings
(including without limitation underlying raw data), Genelabs agrees to provide,
at Genelabs' expense, to Tanabe one copy of any of such portions or information
which are in Genelabs' possession, to the extent not previously provided to
Tanabe, within thirty (30) days after Tanabe's written request identifying such
requested portion or information in reasonable detail (e.g., by title and date
of document or by reference to the applicable citation in the regulatory
filings) and Tanabe's reasonable basis for such request.

                  (b)   Without limiting the information sharing obligations set
forth above in Section 2.4(a), Genelabs agrees that it will make available to
Tanabe any material correspondence between Genelabs and the FDA or U.S. Drug
Enforcement Agency ("DEA") in Genelabs' possession after the Effective Date,
which is not otherwise publicly available to Tanabe, and disclose any material
actions taken by Genelabs, the FDA or the DEA, which (i) relates to Genelabs'
submissions under NDA No. 21-239 and/or EMEA/H/C/531 bearing on the SLE
indication and necessary for Tanabe's fulfillment of its obligations to obtain
regulatory approval for the Tanabe Product in the Territory, (ii) relates to
Genelabs' petition to the FDA and the DEA to obtain a reclassification of
dehydroepiandrosterone from dietary supplements or (iii) which is material and,
either individually or in the aggregate, could reasonably be expected to have a
material adverse effect on (A) Genelabs' clinical development program for the
Prasterone Product for SLE indications or (B) the manufacture or supply of API
or Prasterone Product for SLE indications by or for Genelabs as contemplated
under Section 2.7 and/or Section 5.3. To the extent permissible under Genelabs'
Third Party agreements, including the agreements with Genelabs Licensees and/or
Third Party licensors, Genelabs agrees to grant to Tanabe the exclusive,
sublicensable, royalty-free right under the non-patented rights in, to and under
Genelabs Clinical Data obtained by or for Genelabs from Genelabs Licensees
and/or Third Party licensors including Watson Pharmaceuticals, Inc., to make,
have made, use, sell, offer for sale and import Tanabe Products in the Field in
the Territory.

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            2.5   THIRD PARTY CLINICAL DATA.

                  (a)   With respect to inventions arising out of Tanabe
Clinical Data that is covered by a Valid Claim within a Patent owned by Tanabe,
its Affiliate or Sublicensee (such Patent being a "Tanabe Clinical Data
Patent"), Genelabs shall have an option to license under the following terms.
Tanabe shall notify Genelabs upon the filing of any Tanabe Clinical Data Patent.
If Genelabs elects to license such Tanabe Clinical Data Patent from Tanabe, it
shall provide written notice thereof to Tanabe within six (6) months of
receiving Tanabe's notice of filing and, if Genelabs so elects, Tanabe agrees to
grant and hereby grants to Genelabs an exclusive, fully sublicensable,
royalty-bearing license under all such Tanabe Clinical Data Patents to develop,
make, use, sell, offer for sale and import Prasterone Products in the Field on a
world-wide basis outside the Territory, such license to be subject to mutually
agreed upon reasonable terms and conditions negotiated by the parties in good
faith and to be effective upon Genelabs' giving of notice of its intention to
license such Tanabe Clinical Data Patents. Prior to the expiration of the
foregoing six (6) month option period, Tanabe shall not license or otherwise
encumber such Tanabe Clinical Data Patents to the extent it relates to the scope
of the license set forth in this Section. Tanabe's license to Genelabs under
Tanabe's non-patent rights in, to and under Tanabe Clinical Data shall be
governed by Section 3.3.

                  (b)   With respect to Results owned, invented, generated,
developed, created, originated or conceived by Third Parties (other than Tanabe
Sublicensees which is addressed in Section 3.2) and licensed to Tanabe after the
Effective Date (collectively, "Tanabe Third Party Results"), Tanabe shall
provide prompt written notice to Genelabs describing such Tanabe Third Party
Results in reasonable detail, subject to appropriate confidentiality
obligations. If Genelabs is interested in receiving a license under such Tanabe
Third Party Results, Genelabs shall provide written notice of such interest to
Tanabe within six (6) months after Tanabe's notice hereunder and Tanabe shall
use commercially reasonable efforts to provide for such Tanabe Third Party
Results to be sublicensed to Genelabs hereunder at minimal cost; provided,
however that Genelabs must first agree to pay for any royalties or other
payments due to such Third Party on account of the grant of such sublicense to,
or the exercise of such sublicense by, Genelabs. Tanabe Third Party Results
shall only be included in Tanabe Clinical Data and licensed to Genelabs under
Sections 2.4 (b) and 3.3 hereunder if the Third Party grants Tanabe the right to
sublicense such Tanabe Third Party Results to Genelabs and Genelabs agrees to
receive a license under such Tanabe Third Party Results (at its option) and to
pay for any royalties or other payments resulting from such sublicense or the
exercise thereof.

                  (c)   With respect to Results owned, invented, generated,
developed, created, originated or conceived by Third Parties and licensed to
Genelabs after the Effective Date (collectively, "Genelabs Third Party
Results"), Genelabs shall provide prompt written notice to Tanabe describing
such Genelabs Third Party Results in reasonable detail, subject to appropriate
confidentiality obligations. If Tanabe is interested in receiving a license
under such Genelabs Third Party Results, Tanabe shall provide written notice of
such interest to Genelabs within six (6) months after Genelabs' notice hereunder
and Genelabs shall use commercially reasonable efforts to provide for such
Genelabs Third Party Results to be sublicensed to Tanabe hereunder at minimal
cost; provided, however that Tanabe must first agree to pay for any royalties or
other payments due to such Third Party on account of the grant of such
sublicense to, or the exercise of such sublicense by, Tanabe. Genelabs Third
Party Results shall only be licensed to Tanabe if the Third Party grants
Genelabs the right to sublicense such Genelabs Third Party Results to Tanabe and
Tanabe agrees to receive a license under such Genelabs Third Party Results (at
its option) to pay for any royalties or other payments resulting from such
sublicense or the exercise thereof.

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            2.6   THIRD PARTY IMPROVEMENTS

                  (a)   With respect to Improvements owned, invented, generated,
developed, created, originated or conceived by Third Parties (other than Tanabe
Sublicensees which is addressed in Section 3.2) and licensed to Tanabe after the
Effective Date (collectively, "Tanabe Third Party Improvements"), Tanabe shall
provide prompt written notice to Genelabs describing such Tanabe Third Party
Improvements in reasonable detail, subject to appropriate confidentiality
obligations. If Genelabs is interested in receiving a license under such Tanabe
Third Party Improvements, Genelabs shall provide written notice of such interest
to Tanabe within six (6) months after Tanabe's notice hereunder and Tanabe shall
use commercially reasonable efforts to provide for such Tanabe Third Party
Improvements to be sublicensed to Genelabs hereunder at minimal cost; provided,
however that Genelabs must first agree to pay for any royalties or other
payments due to such Third Party on account of the grant of such sublicense to,
or the exercise of such sublicense by, Genelabs. Tanabe Third Party Improvements
shall only be included in Tanabe Improvements and licensed to Genelabs under
Section 9.4(b) hereunder if the Third Party grants Tanabe the right to
sublicense such Third Party Improvements to Genelabs and Genelabs agrees to
receive a license under such Tanabe Third Party Improvements (at its option) and
to pay for any royalties or other payments resulting from such sublicense or the
exercise thereof.

                  (b)   With respect to Improvements owned, invented, generated,
developed, created, originated or conceived by Third Parties and licensed to
Genelabs after the Effective Date (collectively, "Genelabs Third Party
Improvements"), Genelabs shall provide prompt written notice to Tanabe
describing such Genelabs Third Party Improvements in reasonable detail, subject
to appropriate confidentiality obligations. If Tanabe is interested in receiving
a license under such Genelabs Third Party Improvements, Tanabe shall provide
written notice of such interest to Genelabs within six (6) months after
Genelabs' notice hereunder and Genelabs shall use commercially reasonable
efforts to provide for such Genelabs Third Party Improvements to be sublicensed
to Tanabe hereunder at minimal cost; provided, however that Tanabe must first
agree to pay for any royalties or other payments due to such Third Party on
account of the grant of such sublicense to, or the exercise of such sublicense
by, Tanabe. Genelabs Third Party Improvements shall only be licensed to Tanabe
if the Third Party grants Genelabs the right to sublicense such Genelabs Third
Party Improvements to Tanabe and Tanabe agrees to receive a license under such
Genelabs Third Party Improvements (at its option) and to pay for any royalties
or other payments resulting from such sublicense or the exercise thereof.

            2.7   ADVERSE DRUG EVENT REPORTING. If either party becomes aware of
any serious adverse event relating to the API, Prasterone Product or Tanabe
Product, such party shall promptly inform the other of such event and comply
with Applicable Laws with respect to the reporting and treatment of such event.

3.    LICENSE GRANTS.

            3.1   LICENSE TO TANABE. Subject to the terms and conditions of this
Agreement, Genelabs hereby grants to Tanabe (a) a nontransferable (except in
accordance with Section 18.2), royalty bearing, exclusive license (exclusive
even as to Genelabs) in the Territory, including the right to grant sublicenses
(in accordance with Section 3.2), under all of Genelabs' right, title and
interest, in, to and under Genelabs Patents, Genelabs Know-How, Genelabs
Clinical Data, Joint Patents and Genelabs Improvement Patents to develop,
register, make and have made, use, sell, offer to sell, and import Tanabe
Products (and to have such rights exercised on Tanabe's behalf by Third Parties)
within the Field and in the Territory and (b) a nontransferable (except in
accordance with Section 18.2), royalty-free exclusive license (exclusive even as
to Genelabs) in the Territory, including the right to grant sublicenses (in
accordance with Section 3.2) under all of Genelabs' right, title and interest
in, to and under intellectual property rights covering non-patented Genelabs
Improvements to develop, register, make and have made, use, sell, offer to sell,
and

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

import Tanabe Products (and to have such rights exercised on Tanabe's behalf by
Third Parties) within the Field and in the Territory. The foregoing license is
subject to Genelabs' right to make, supply and import Tanabe Products for sale
by Tanabe or its designees in the Territory, and Tanabe's right to purchase the
same for sale by itself or its designees, both in accordance with this Agreement
and the M&S Agreement (as defined in Section 7.2). Genelabs agrees that Tanabe
may appoint one or more Third Party contractors to exercise Tanabe's rights or
fulfill Tanabe's obligations under this Agreement after receiving Genelabs'
prior written consent to such appointment; provided however that contract
research organizations and/or contract sales forces appointed by Tanabe, in the
ordinary course of business and subject to consultation with the JSC, to
exercise Tanabe's rights or to fulfill Tanabe's obligations under this Agreement
shall not require Genelabs' prior written consent thereto. In such case, Tanabe
shall first obtain from such Third Party contractors the written agreements
under which they undertake substantially the same obligations of Tanabe under
this Agreement, including without limitation obligations with respect to
confidentiality and licensing of intellectual property, and Tanabe shall be
responsible for the performance of the obligations by them.

            3.2   SUBLICENSE RIGHTS. Tanabe shall be entitled to sublicense the
rights granted to it under Section 3.1 and 15.2 subject to Genelabs' prior
written approval. Accordingly, prior to entering into any such sublicense with a
Third Party, Tanabe shall provide to Genelabs (a) a copy of a reasonably
detailed termsheet between Tanabe and such Third Party in English translation
for Genelabs' general review and approval, not to be unreasonably withheld or
delayed, and (b) a copy of the final sublicense agreement as agreed to but not
yet executed by Tanabe and such Third Party in English translation for Genelabs'
final review and approval, not to be unreasonably withheld or delayed. Genelabs
shall provide Tanabe with its decision on the termsheet provided hereunder as
soon as reasonably possible but no longer than thirty (30) days after Genelabs'
receipt thereof and its decision on such sublicense agreement provided hereunder
as soon as reasonably possible but no longer than thirty (30) days after
Genelabs' receipt thereof. Tanabe may only enter into such sublicense agreement
after receiving such written approval from Genelabs on such term sheet and such
sublicense agreement; provided however that in case Tanabe does not receive any
response from Genelabs within thirty (30) days of the providing such agreed upon
agreement to Genelabs, such agreement shall be deemed approved by Genelabs.
Tanabe shall provide to Genelabs a copy of any such executed sublicense
agreement within thirty (30) days after such execution. Without limiting any of
the foregoing obligations, any agreement between Tanabe and each such proposed
sublicensee shall be subject to this Agreement and provide for terms and
conditions consistent with, and at least as protective of Genelabs and its
rights as, the terms and conditions contained in this Agreement. For the
avoidance of doubt, Tanabe shall require all Tanabe Sublicensees to grant Tanabe
the right under all of such Sublicensee's rights in any Tanabe Clinical Data and
Tanabe Improvements (including Tanabe Clinical Data Patents and Tanabe
Improvement Patents) to fully sublicense such rights to Genelabs in accordance
with the licenses set forth in Sections 2.5(a), 2.5(b), 3.3 and 9.4(b).
Furthermore, as applicable, all Sublicensees shall be obligated to perform those
obligations of Tanabe applicable to the sublicensed rights as if it were Tanabe
hereunder. Upon execution of such agreement, Tanabe shall provide Genelabs with
an unredacted copy of such executed agreement, including an English translation
thereof if applicable.

            3.3   TANABE CLINICAL DATA AND JOINT PATENTS. Subject to the terms
and conditions of this Agreement, Tanabe hereby grants to Genelabs an exclusive
(solely with respect to the Tanabe Clinical Data), sublicensable (subject to
Section 2.4(a) solely with respect to the Tanabe Clinical Data), royalty-free
license under Tanabe's rights (excluding patent rights) in, to and under Tanabe
Clinical Data and Joint Patents to make, have made, use, sell, offer for sale
and import Prasterone Products in the Field world-wide except in the Territory.

            3.4   NO OTHER RIGHTS; AFFIRMATIVE COVENANTS. Tanabe acknowledges
and agrees that Genelabs and its licensors shall retain ownership of the
Genelabs Patents, Genelabs Know-How,

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

Genelabs Clinical Data, Genelabs Improvement Patents and Genelabs' right, title
and interest in the Joint Patents, subject only to the rights and licenses
granted to Tanabe herein. Except as expressly provided herein, no ownership
right, title, or interest is granted (by implication or otherwise) by Genelabs
to Tanabe in, to or under Genelabs Patents, Genelabs Know-How, Genelabs Clinical
Data, Genelabs Improvement Patents. Genelabs acknowledges and agrees that Tanabe
and its licensors shall retain ownership of the Tanabe Improvement Patents,
Tanabe Clinical Data and Tanabe's right, title and interest in the Joint
Patents, subject only to the rights and licenses granted to Genelabs herein.
Except as expressly provided herein, no ownership right, title, or interest is
granted (by implication or otherwise) by Tanabe to Genelabs in, to or under the
Tanabe Improvement Patents, Tanabe Clinical Data or Tanabe's right, title and
interest in the Joint Patents.

            3.5   AFFIRMATIVE COVENANTS. During the term of this Agreement and
subject to any conversion of the license grant to Tanabe pursuant to Section
5.2, Genelabs covenants that it shall not grant any licenses in, to or under the
Genelabs Patents, Genelabs Improvement Patents, Joint Patents, Genelabs Clinical
Data and/or Genelabs Know-How (or, if applicable Genelabs Third Party Results
and/or Genelabs Third Party Improvements) to develop, register, make and have
made, use, sell, offer to sell, and import Prasterone Products within the Field
and in the Territory. Tanabe covenants that, during the term of this Agreement,
it shall not develop, register, make, have made, use, sell, offer to sell, or
import Tanabe Products other than in the Field in the Territory.

            3.6   REGISTRATION OF EXCLUSIVE LICENSE. Genelabs and Tanabe agree
to execute a formal license agreement reflecting the terms and conditions of the
licenses granted in this Agreement for the purpose of registering the exclusive
patent license and trademark license granted under this Agreement with the
Japanese Patent Office. In respect of each Genelabs Patents and/or Genelabs
Improvement Patents, such registration shall be made as an exclusive license
("Senyo-jisshi-en") set forth in Section 77 of Japanese Patent Law; provided
however that such registration shall in no way expand upon the scope of rights
granted to Tanabe in this Agreement. Upon Tanabe's written request and at
Tanabe's expense, Genelabs shall assist Tanabe in effecting such registration by
executing such formal license agreement and delivering all other reasonably
necessary instruments and documents. Notwithstanding the foregoing, Tanabe shall
not establish any pledges on, or otherwise grant any security interests in, any
Genelabs Patents and/or Genelabs Improvement Patents to a Third Party without
the prior written consent of Genelabs.

4.    REGULATORY FILINGS.

            4.1   PREPARATION OF REGULATORY FILINGS. Tanabe and its Affiliates
shall use commercially reasonable efforts in filing for and obtaining Regulatory
Approval for Tanabe Products in the Territory and shall conduct such efforts in
accordance with the Product Development Plan and the express terms and
conditions of this Agreement. During the term of this Agreement, upon Tanabe's
reasonable written request, Genelabs shall provide Tanabe with reasonable
assistance in obtaining Regulatory Approval which is not otherwise expressly
stated herein for Tanabe Products at Tanabe's expense. All regulatory filings by
Tanabe for Tanabe Products shall constitute the sole property of Tanabe except
to the extent otherwise provided in this Article 4.

            4.2   RIGHTS TO REGULATORY FILINGS.

                  (a)   Subject to the terms and conditions of this Agreement,
for the term of this Agreement, Tanabe and Tanabe Sublicensees shall have, and
Genelabs hereby grants to Tanabe and Tanabe Sublicensees, a right of reference
to Genelabs' NDA No. 21-239 and EMEA/H/C/531 to the extent useful or necessary
for, and solely for the purposes of, preparing, filing or maintaining Tanabe's
regulatory filings for, and obtaining Regulatory Approval of, Tanabe Products in
the Territory. Pursuant

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

to this right of reference and with respect to the regulatory files for
Genelabs' NDA No. 21-239 and EMEA/H/C/531 provided to Tanabe in accordance with
Section 2.4(a), Tanabe may inspect, copy or forward to appropriate regulatory
authorities such NDA and such European filings as necessary or appropriate for
the commercialization of Tanabe Products in the Territory. Upon Tanabe's
reasonable written request, Genelabs shall provide appropriate information,
consents and notices to the FDA and other regulatory authorities as are useful
or necessary for Tanabe to effectuate the rights of reference granted to it in
this Section 4.2(a). Genelabs shall keep Tanabe reasonably informed in writing,
on a regular basis, of material developments relating to Prasterone Product
regulatory filings outside the Territory.

                  (b)   Tanabe and Tanabe Sublicensees shall be responsible for
preparing, filing and maintaining all regulatory dossiers and other filings
covering Tanabe Products in the Territory which Tanabe reasonably deems
appropriate. Tanabe or its designee shall be responsible for all interactions
with Competent Authorities relating thereto. Genelabs will, at Tanabe's
reasonable request and expense, prepare those sections of Tanabe's regulatory
filings covering Tanabe Products in the Territory related to Genelabs'
activities under this Agreement, and shall otherwise cooperate, as reasonably
requested by Tanabe and at Tanabe's expense, in the preparation and maintenance
of such regulatory filings. In addition, at Tanabe's reasonable request,
Genelabs shall make appropriate personnel reasonably available for meetings with
Competent Authorities when related to Tanabe Products. For the avoidance of
doubt, nothing in this Section shall be construed to oblige Genelabs to carry
out any additional studies requested by Tanabe which is specifically necessary
to prepare and maintain such regulatory filings in the Territory. Genelabs shall
have the right to have one or more of its employees or agents attend meetings of
Competent Authorities at its own expense. Tanabe shall keep Genelabs reasonably
informed in writing, on a regular basis, of material developments relating to
Tanabe Product regulatory filings.

                  (c)   Subject to the terms and conditions of this Agreement,
Tanabe hereby grants to Genelabs, its Affiliates and sublicensees, a right of
reference to any of Tanabe's regulatory filings for Tanabe Products, to the
extent necessary for, and solely for the purposes of, preparing, filing or
maintaining regulatory filings for, and obtaining Regulatory Approval of,
Prasterone Products outside the Territory. Genelabs may inspect and copy, at
Genelabs' expense, such filings as necessary or appropriate for the
commercialization of Prasterone Products outside the Territory. Upon Genelabs'
reasonable written request, Tanabe shall provide appropriate information,
consents and notices to the FDA and other regulatory authorities (including
without limitation the European Medicines Evaluation Agency) as are necessary
for Genelabs to effectuate the rights of reference granted to Genelabs in this
Section 4.2(c).

            4.3   NOTICE OF COMMUNICATION WITH REGULATORY AUTHORITIES. In
addition to the parties' reporting obligations under Section 4.2(a) and (b),
each party shall notify the other party of any written communications to or from
regulatory authorities on matters related to Prasterone Products or which may
reasonably be deemed to impact Tanabe Product development, manufacture or
regulatory approval in the other party's territory, and shall provide the other
party, upon the other party's request, with copies of any such written
communications (including an English summary thereof, if the original is not in
English ) promptly after the request thereof.

5.    COMMERCIALIZATION OBLIGATIONS.

            5.1   COMMERCIALIZATION DILIGENCE. Tanabe shall use commercially
reasonable, good faith efforts in connection with the marketing, promotion and
sales of Tanabe Products in the Territory with the goal of maximizing Net Sales
of Tanabe Products in the Territory. Without limiting the foregoing, Tanabe's
efforts under this Article 5 shall be in accordance with the applicable
Commercialization Plan, which has been approved by the JSC in accordance with
Section 5.2, this Agreement and all relevant Applicable Laws.

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

            5.2   COMMERCIALIZATION PLAN. Reasonably prior to the planned
commercial launch of Tanabe Products, Tanabe shall prepare a good faith,
commercially reasonable written commercialization plan ("Commercialization
Plan") for Tanabe Products in the Territory and submit such plan to the JSC at
least twelve (12) months before such planned launch for the committee's review
and approval. The Commercialization Plan will set forth in reasonable detail the
Tanabe Products' marketing and selling objectives, strategy and tactics for the
forthcoming calendar year, reasonable and good faith sales forecasts consistent
with Tanabe's actual commercially reasonable projected sales and other matters
appropriate and customary in the industry for such a plan, all of which shall
take into consideration reasonable market conditions and the experience and
perspective of Tanabe with respect to optimal marketing and selling practices in
the Territory. The Commercialization Plan will be discussed and reviewed
annually by appropriate representatives from each party and the final proposed
plan will be submitted to the JSC for its review and approval within ninety (90)
days before the end of each calendar year. Each Commercialization Plan shall
include the level of promotional and detailing effort necessary for Tanabe to at
least achieve the forecast described in the Commercialization Plan. If (i)
during either the ** or ** calendar years after the commercial launch of Tanabe
Products in the Territory, Tanabe's unit sales of Tanabe Products are less than
**, or (ii) during the ** calendar year after commercial launch of Tanabe
Products or any calendar year thereafter, Tanabe's unit sales of Tanabe Products
are less than **, and Tanabe's failure to achieve such unit sales of Tanabe
Products is not due to **, then Genelabs shall have the option to convert any
exclusive license under the Agreement for Tanabe Products into a non-exclusive
appointment and license upon ninety (90) days prior written notice to Tanabe. If
Genelabs converts the exclusive appointment and license under this Agreement to
a non-exclusive license, then Tanabe hereby agrees to allow and cooperate in
co-marketing of Tanabe Products in the Territory by Genelabs and/or designated
Third Parties under Tanabe's regulatory approval for Tanabe Products and under
the same Trademark (as such term is defined in Section 15.1) or Tanabe Trademark
(as such term is defined in Section 15.3) used by Tanabe in the Territory.

            5.3   ADVERSE DRUG EVENT REPORTING. Each party shall advise the
other, by telephone or facsimile, within such time as is required to comply with
Applicable Laws (but in any event promptly), after it becomes aware of any
potentially serious or unexpected adverse event (including adverse drug
experiences, as defined in 21 C.F.R. Section 314.80 or other applicable
regulations) involving Tanabe Products' development, use or commercialization in
the Territory (an "ADE"). Each party shall provide the other with a written
report delivered by confirmed facsimile of any ADE, stating the full facts known
to it, including but not limited to customer name, address, telephone number,
batch, lot and serial numbers, and other information as required by Applicable
Laws to the extent such ADE arises in the course of its development, use or
commercialization of Tanabe Product or Prasterone Product in its respective
territory (i.e. Japan for Tanabe, outside Japan for Genelabs). Each party shall
have responsibility, with reasonable assistance from the other for (i)
monitoring such ADE; (ii) data collection activities that occur between itself
and the patient and medical professional, or that are provided to it by the
other party, as appropriate, including any follow-up inquiries which it deems
necessary or appropriate; and (iii) making any reports to the Competent
Authorities in its respective territory. In the event either party requires
information regarding ADE with respect to reports required to be filed by it in
order to comply with Applicable Laws, including obligations to report ADEs to
the FDA or Competent Authorities, each party agrees to provide such information
to the other on a timely basis. Each party agrees to translate any non-English
documents to be provided under this Section 5.3 to the other into English.
Reasonably prior to the initiation of the clinical studies for the first Tanabe
Product, the parties shall agree upon additional standard operating procedures
for handling such ADE's in compliance with Applicable Laws.

            5.4   INTERNATIONAL MARKETING STRATEGIES. Genelabs plans to hold
periodic internal marketing strategy meetings to remain informed of any new
plans or marketing studies to be conducted by Genelabs Licensees under Genelabs
Patents and Genelabs Know-How for the manufacture, use and sale of Prasterone
Products for the SLE indication ("Genelabs Licensees"). Furthermore, Genelabs
agrees to use

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

commercially reasonable efforts to organize an international marketing strategy
meeting involving Genelabs Licensees. The purpose of such meeting would be to
discuss, under suitable confidentiality restrictions and subject to the terms
and conditions of the applicable license agreements, marketing and
commercialization strategies with the goal of maximizing the sale of Prasterone
Products worldwide.

            5.5   RECALL. The Parties agree that the M&S Agreement (as such term
is defined in Section 7.2) shall govern the management of any recall of a Tanabe
Product. Notwithstanding the foregoing, in the event that Tanabe or the
Regulatory Authority determines that a Tanabe Products recall or withdrawal in
the Territory is necessary, then Tanabe shall take all actions appropriate in
order to recall or withdraw such Tanabe Products. In case Tanabe determines that
a Tanabe Products recall or withdrawal in the Territory is necessary without any
decision of the Regulatory Authority, then it shall consult with Genelabs prior
to taking any action with respect to the Tanabe Products. Genelabs shall
reimburse Tanabe only for all reasonable out-of-pocket expenses (excluding any
claimed loss of profits, prospective sales, goodwill or any other indirect loss)
associated with any such recall or withdrawal caused in whole by the negligence
of Genelabs or by Genelabs' failure to manufacture the Tanabe Products in
accordance with the requirements of the M&S Agreement. Tanabe shall reimburse
Genelabs only for all reasonable out-of-pocket expenses (excluding any claimed
loss of profits, prospective sales, goodwill or any other indirect loss)
associated with any such recall or withdrawal caused in whole by the negligence
of Tanabe or by Tanabe's failure to comply with the terms and conditions of this
Agreement or any applicable regulatory requirements. In the event that any
Tanabe Products recall or withdrawal is caused in part by the negligence of
Tanabe and in part by the negligence of Genelabs, the Parties' direct
out-of-pocket expenses shall be apportioned between Genelabs and Tanabe in
relation to each Party's respective negligent acts or omissions.

6.    PAYMENT OBLIGATIONS.

            6.1   INITIAL CONSIDERATION.

                  (a)   In consideration of the clinical supply and as
reimbursement for the portion of FTE engaged in the ongoing development work,
Tanabe shall pay to Genelabs two million dollars (U.S. $2,000,000) upon
execution of this Agreement. This payment shall be non-refundable and
non-creditable. Prior to payment of such amount by Tanabe, Genelabs will provide
to Tanabe a written invoice regarding ongoing clinical development work in
Prasterone Product by Genelabs FTEs.

                  (b)   Tanabe shall make the following equity investment
("Equity Investment") in Genelabs upon execution of this Agreement ("Investment
Date") all in accordance with and subject to the terms and conditions of the
stock purchase agreement to be entered into by the parties of even date herewith
(the "Stock Purchase Agreement"): Tanabe shall purchase the number of shares
purchasable with U.S. $2,600,000 with each share to be purchased at the price
set forth in the Stock Purchase Agreement.

                  (c)   Tanabe shall issue irrevocable instructions to its bank
to transfer by wire the initial consideration in Section 6.1(a) and the Equity
Investment in Section 6.1(b), in accordance with Genelabs' written instructions,
to Genelabs within twenty-four (24) hours after execution of this Agreement. The
foregoing payment obligation is unconditional, and Tanabe shall not have any
rights under this Agreement or under the Stock Purchase Agreement until such
payment is received by Genelabs.

            6.2   MILESTONE PAYMENTS.

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

                  (a)   Tanabe shall make the following non-refundable,
non-creditable milestone payments (the "Milestone Payments") to Genelabs within
thirty (30) days after Tanabe's achievement of the applicable milestone for
Tanabe Products set forth below.

<TABLE>
<CAPTION>
                      Milestone Event                                  Milestone Payment
                      ---------------                                  -----------------
<S>                                                          <C>
Initiation of Pivotal/Bridging Study (i.e., Phase II/III)    U.S. $2,000,000
in Japan
Filing of NDA in Japan                                       U.S. $2,000,000
National Health Insurance ("NHI") Price Listing in Japan     U.S. $6,000,000 (subject to Section 6.2(b))
</TABLE>

                  (b)   Tanabe shall pay a non-refundable, non-creditable six
million dollar (U.S. $6,000,000) milestone payment to Genelabs within thirty
(30) days after a Tanabe Product has been added to the NHI Price List in Japan,
provided however that if the MHLW only grants the indication of ** in the
initial labeling for such Tanabe Product, such initial milestone payment shall
be reduced to ** dollars (U.S. $**) or if only ** is granted in the initial
labeling, such initial milestone payment shall be reduced to ** dollars (U.S.
$**); provided however that if such initial labeling is subsequently expanded to
include other indications (including, without limitation, ** in the event Tanabe
only obtained initial labeling for ** or ** in the event that Tanabe only
obtained initial labeling for **), Tanabe shall provide Genelabs with prompt
written notice of such additional labeling right and pay to Genelabs the unpaid
remainder of the U.S. $6,000,000 milestone for NHI price listing in Japan within
thirty (30) days after obtaining such additional labeling right. For the
avoidance of doubt, in all other circumstances except for the two expressly set
forth above (i.e., Tanabe is only granted ** or ** in the initial labeling for
Tanabe Products), Tanabe shall make the full NHI price listing milestone payment
to Genelabs. Notwithstanding the foregoing potential initial milestone
reduction, in the event that Tanabe elects, in its sole discretion pursuant to
Section 2.3, to pursue the development and/or regulatory approval, including
without limitation NHI listing, of only one indication referenced above (i.e.,
** or **) under this Agreement, Tanabe shall provide Genelabs with prompt
written notice of such election and Tanabe shall make the full NHI price listing
milestone payment of six million dollars (U.S. $6,000,000) to Genelabs within
thirty (30) days after achieving such milestone, regardless of the indication(s)
is included in the labeling for the applicable Tanabe Product.

            6.3   ROYALTIES.

                  (a)   Subject to the provisions of this Section 6.3 and the
terms and conditions of this Agreement, in consideration for the license granted
to Tanabe under Section 3.1, Tanabe shall pay to Genelabs incremental royalties
based on the cumulative annual Net Sales of all Tanabe Products sold in the
Territory by Tanabe, its Affiliates and Tanabe Sublicensees as follows:

                        (i)   ** percent (**%) of the portion of annual Net
Sales for such calendar year which are equal to or less than U.S. ** dollars
(U.S. $**); and

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

                        (ii)  ** percent (**%) of the portion of annual Net
Sales for such calendar year which are greater than U.S. ** dollars (U.S. $**)
but less than or equal to U.S. ** dollars (U.S. $**); and

                        (iii) ** percent (**%) of the portion of annual Net
Sales for such calendar year which are greater than U.S. ** dollars (U.S. $**).

                  (b)   For the avoidance of doubt, the cumulative annual Net
Sales for any given calendar year shall be reset to zero upon the beginning of
the subsequent calendar year for purposes of applying the applicable royalty
rate under Section 6.3(a).

            6.4   ROYALTY PAYMENT TERMS.

                  (a)   Within fifteen (15) days after the end of each calendar
month, Tanabe shall provide to Genelabs a written report setting forth (i) the
calendar month covered by such report; (ii) a good faith estimate of the gross
sales and Net Sales for such month; and (iii) the estimated accrued royalties
for such month. The foregoing report shall cover sales activity by Tanabe, its
Affiliates and Tanabe Sublicensees.

                  (b)   Payments due under Section 6.3 shall be payable within
thirty (30) calendar days after the end of each calendar quarter with respect to
Net Sales in such quarter. Each such payment shall be accompanied by a written
report ("Quarterly Report") showing: (i) the calendar quarter for which such
payment applies; (ii) the gross amount billed to Third Parties for Tanabe
Products during such quarter; (iii) the total deductions from the amount billed
to arrive at Net Sales; and (iv) the amount of royalties due under Section 6.2.
The foregoing report shall cover sales activity by Tanabe, its Affiliates and
Tanabe Sublicensees. Tanabe shall require its Sublicensees to prepare similar
reports with respect to Sublicensee sales activities (excluding item (iv)) and
Tanabe shall make such Sublicensee reports available to Genelabs upon request.
Any late payments under this Agreement shall bear interest at a rate of prime
plus two percent (2%) per annum, or the maximum rate permitted by law, whichever
is less.

                  (c)   Tanabe's obligation to pay the full royalty amount to
Genelabs under Section 6.3 shall begin with the first commercial sale of a
Tanabe Product by Tanabe, its Affiliate or a Tanabe Sublicensee, and, subject to
Section 6.5, continue until the end of the royalty term as set forth in Section
6.9. No reduction of the royalty amounts set forth in Section 6.3 shall occur
unless and until, and solely in the event that, the conditions therefore under
Section 6.5 are satisfied.

            6.5   ROYALTY STEP-DOWN.

                  (a)   Provided that Tanabe's royalty obligations under Section
6.3 have not already been reduced under Section 6.5(b) (that is either Section
6.5(a) or (b) will apply to such royalty obligations, but not both), such
royalty obligations shall be reduced by ** of what would otherwise be due
pursuant to Section 6.3(a) (i.e., only ** of the royalty rates under Section
6.3(a) would apply to Net Sales) upon the occurrence of the later of (i) the
expiration, disclaimer or final (unappealed or unappealable) determination of
invalidity or unenforceability by a court or authority of competent jurisdiction
of the last Valid Claim within the Genelabs Patents, Joint Patents or the
Genelabs Improvement Patents in the Territory, or (ii) the expiration of the
last to expire of any regulatory or data exclusivity period (i.e.,
saishinsa-kikan, including without limitation those exclusivities afforded
through orphan designation). If reduced hereunder, such royalties shall remain
at such reduced level for the remainder of the royalty term of this Agreement.

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<PAGE>

                                             ** CONFIDENTIAL TREATMENT REQUESTED

                  (b)   Provided that Tanabe's royalty obligations under Section
6.3 have not already been reduced under Section 6.5(a) (that is either Section
6.5(a) or (b) will apply to such royalty obligations, but not both), Tanabe's
royalty obligations under Section 6.3 with respect to Net Sales of Tanabe
Products for SLE shall be reduced by ** of what would otherwise be due pursuant
to Section 6.3(a) (i.e., only ** of the royalty rates under Section 6.3(a) would
apply to Net Sales) upon the general commercial availability of a Competitive
Product in the Territory; provided that, and only during the period during
which, there exists no Valid Claim within the Genelabs Patents, Joint Patents or
Genelabs Improvement Patents in the Territory.

                  Tanabe shall continue to pay royalties under Section 6.3(a) at
this reduced rate for as long as (but only for so long as) such Competitive
Product remains on the market in the Territory. For purposes of this Section
6.5(b), "Competitive Product" shall mean a Prasterone Product, developed and
commercialized by a Third Party who is not a Tanabe Sublicensee or an Affiliate,
collaborator or other licensee of Tanabe, which Prasterone Product has received
Regulatory Approval for the treatment of a SLE indication and the sales of which
have a significant adverse impact upon the sales of Tanabe Products in the
Territory.

            6.6   CURRENCY OF PAYMENT. All payments to be made under this
Agreement shall be made in U.S. Dollars. Net Sales shall be first determined in
Japanese Yen and shall be converted quarterly into an amount in U.S. Dollars at
the average of the bid and ask prices reported in the Wall Street Journal as of
the close of the last business day of such quarter in which such royalty is due.

            6.7   SINGLE ROYALTY. No multiple royalties or payments related to
Net Sales shall be payable hereunder because the relevant Tanabe Product, its
manufacture, sale or use is covered by more than one Valid Claim within the
Genelabs Patents or Genelabs Improvement Patents.

            6.8   TAXES. Each party shall be responsible for and pay all taxes,
duties and levies directly imposed by all foreign, federal, state, local or
other taxing authorities (including, without limitation, export, sales, use,
excise, and value-added taxes) based on such party's transactions or payments
under this Agreement, other than taxes imposed or based on the other party's net
income. In the event that Tanabe is prohibited by law from remitting payments to
Genelabs unless Tanabe deducts or withholds taxes therefrom on behalf of the
local taxing jurisdiction, then Tanabe shall:

                  (a)   deduct those taxes from the otherwise remittable
payments,

                  (b)   timely pay the taxes to the proper tax authority in
accordance with applicable law, and

                  (c)   give Genelabs any reasonable assistance, which shall
include the provision of such documentation as may be required by the tax
authority to enable Genelabs to claim exemption from or obtain a tax credit,
repayment of or reduction of tax. All taxes levied on a party's net income
arising from the effect of this Agreement shall be borne by such party.

            6.9   ROYALTY TERM. Tanabe's royalty obligations under Section 6.3
shall terminate upon the later of (i) the expiration, disclaimer or final
(unappealed or unappealable) determination of invalidity or unenforceability by
a court or authority of competent jurisdiction of the last Valid Claim within
the Genelabs Patents, Joint Patents, or Genelabs Improvement Patents in the
Territory which, absent rights hereunder, would be infringed by the development,
manufacture, use, importation, sale or offer for sale of Tanabe Products or (ii)
ten (10) years after the first commercial launch of a Tanabe Product.
Notwithstanding the above, (a) Tanabe shall be obligated after expiration of the
royalty term to pay any

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

royalty amounts that accrued under Section 6.3 prior to such expiration, and (b)
after expiration of the ten (10)-year period following the first commercial
launch of a Tanabe Product, if for purposes of the foregoing clause (i), the
only unexpired, non-disclaimed, valid and enforceable Valid Claim(s) (as
described in clause (i)) is within the Joint Patents and not within the Genelabs
Patents or the Genelabs Improvement Patents, then Tanabe's royalty obligations
shall be reduced by ** of what would otherwise be due pursuant to Section 6.3(a)
or 6.5(b). For the avoidance of doubt, if the foregoing Section 6.9(b) event and
Section 6.5(b) event occurs, then Tanabe's royalty obligations shall be ** of
what would otherwise be due pursuant to Section 6.3(a).

7.    SUPPLY OBLIGATIONS.

            7.1   SUPPLY OF API AND PRASTERONE PRODUCT FOR PRE-CLINICAL AND
CLINICAL USE.

                  (a)   Genelabs shall supply Tanabe with API and Prasterone
Product in capsule form reasonably necessary for Tanabe to conduct any
pre-clinical studies, formulation development and clinical studies required to
obtain Regulatory Approval for Tanabe Products in the Territory at Genelabs'
cost, which is included in the Initial Consideration set forth in Section
6.1(a); provided however that Genelabs' obligation to supply API and Prasterone
Product in capsule form under this Section 7.1(a) shall not exceed in the
aggregate five hundred kilograms total of API (500 kg total), with Prasterone
Product not to exceed 10% of the total API.

                  (b)   Unless otherwise agreed to in writing by the parties,
all deliveries by Genelabs of API hereunder shall be F.C.A. Genelabs' or its
Third Party subcontractor's facility (Incoterms 2000) by means of a common
carrier reasonably designated by Tanabe or, in the absence of Tanabe's
designation, to a common carrier reasonably chosen by Genelabs. Tanabe shall
bear the risk of loss to any units of API and/or Prasterone Product in capsule
form from the F.C.A. point of delivery (at which point all title to such API
shall pass to Tanabe). Tanabe shall be responsible for all risk and expense
(including without limitation all delivery, freight, handling, taxes, tariffs,
duties and insurance related expenses) after the deliveries made by Genelabs to
Tanabe under this Section 7.1; for the avoidance of doubt, however, in no event
shall Tanabe be required to pay any amounts to Genelabs that have already been
paid by Tanabe pursuant to Section 7.2(a) and/or 7.2(b).

            7.2   SUPPLY OF API AND PRASTERONE PRODUCT FOR COMMERCIAL EFFORTS.
Within twelve (12) months of the Effective Date, Tanabe and Genelabs shall
negotiate in good faith and enter into a manufacturing and supply agreement
("M&S Agreement") for the supply of API and/or Prasterone Product, polymorphic
form 1 in 50mg capsules, to or for Tanabe by Genelabs for commercial purposes,
containing the following terms and such other reasonable terms and conditions as
the parties may mutually agree:

                  (a)   Genelabs shall provide for the manufacture of and supply
to Tanabe, and Tanabe shall purchase from Genelabs, API on such time schedules
as are agreed upon by the parties in the M&S Agreement at a price equaling the
sum of ** thereof.

                  (b)   If Tanabe intends to sell as Tanabe Products the capsule
forms of Prasterone Products developed by Genelabs, Genelabs shall, at Tanabe's
request, provide for the manufacture of and supply to Tanabe, and Tanabe shall
purchase from Genelabs, Prasterone Product in capsule form for Tanabe's
commercial use as Tanabe Products in such quantities and on such time schedules
agreed upon by the parties in the M&S Agreement at a price equaling the sum of
** thereof.

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

                  (c)   Each party shall have the right to terminate the M&S
Agreement upon the termination of Tanabe's royalty obligations as provided in
Section 6.9; provided however, that Genelabs shall use reasonable efforts to
facilitate Tanabe's securing an alternative supply source for Tanabe Product in
the event of such termination of the M&S Agreement.

                  (d)   The M&S Agreement will include other provisions
customarily found in agreements for products of similar nature, as mutually and
reasonably agreed upon by the parties.

                  (e)   Upon the initiation of negotiations by the parties of
the M&S Agreement, Tanabe shall propose, subject to Genelabs' reasonable
approval, a reasonable, initial written forecast of estimated purchases of API
and, if applicable, Prasterone Product in capsule form over the next five (5)
years for purposes of setting Genelabs' manufacturing capacity. For the
avoidance of doubt, this forecast shall be for facility and material planning
purposes only and shall not constitute a firm order. The M&S Agreement shall
provide for periodic review and updating of such forecast, such review and
updating to occur on at least a quarterly basis. In addition to the foregoing,
the M&S Agreement shall contain binding and partially binding forecasting
mechanisms, to be periodically updated, and provisions for firm purchase orders
which must be within certain agreed parameters as compared to forecasted
amounts.

                  (f)   Subject to the terms, conditions and specifications for
API and Prasterone Product as referenced NDA No. 21-239 and/or EMEA/H/C/531, and
any amendments thereto, and as agreed to by Genelabs in Genelabs' Third Party
manufacturing and supply agreements, as amended, the M&S Agreement shall
address, inter alia, specifications to be used for the acceptance for the supply
of both API and Tanabe Product, respectively, both of which shall be agreeable
to both parties (provided that the initial specifications for API and Prasterone
Product submitted by Genelabs from Genelabs' Third Party manufacturing contracts
and reviewed by Tanabe are agreeable to the parties), take into account
amendments to the specifications required by the MHLW required for Regulatory
Approval of the Tanabe Product and API (in which event Tanabe shall provide
written notice to Genelabs of such required amendment and Genelabs shall use
reasonable efforts to obtain its Third Party manufacturing contractors'
agreement to amend the specifications for supply of Tanabe Product or API in
accordance with the MHLW requirements and, in the event a Third Party
manufacturer refuses to agree to the amended specifications, then Genelabs will
use reasonable efforts to work with Tanabe to secure an alternative to such
Third Party manufacturer under such amended specifications) and shall be
attached to the M&S Agreement; audit right to the manufacturing site and
manufacturing records, related quality and environmental controls; procedures
for ensuring pro-active COGS management by Genelabs; Genelabs' right to make
process changes that does not affect agreed specifications or which does not
require Tanabe to conduct additional non-clinical or clinical studies, subject
to Tanabe being given a reasonably sufficient time to deal with revision of the
Regulatory Approvals and Genelabs' obligation to delay such change until Tanabe
is able to achieve such revision; procedures for release/testing; Tanabe's
rights to demand a refund or replacement in case of release/testing
non-compliance or detection of any latent defect, cost reimbursement procedures
in case of recall attributable to Genelabs' responsibility defined under the
terms of this Agreement or the M&S Agreement; procedures appropriately
addressing temporary rights in the event, or the likely event, of the occurrence
of any default in supply and/or prolonged force majeure event, which includes
preparation of dual manufacturing source. The specifications to be used
temporarily between the parties for the supply of API and/or Prasterone Product
prior to the M&S Agreement being agreed to shall reference Genelabs' NDA No.
21-239.

8.    RECORD KEEPING, RECORD RETENTION AND AUDITS.

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<PAGE>

                                             ** CONFIDENTIAL TREATMENT REQUESTED

            8.1   RECORD KEEPING. Each party shall require its employees,
consultants and Third Party contractors to disclose any inventions arising under
the Agreement in writing promptly after conception.

            8.2   RECORDS RETENTION. Tanabe shall keep complete and accurate
records of its regulatory communications and development and commercialization
activities related to Tanabe Products in sufficient detail to permit Genelabs to
confirm, in accordance with Section 8.3, the accuracy of calculations of all
payments made under Article 6. Tanabe shall also require Tanabe Sublicensees to
keep similar records and to provide reasonable access to Tanabe or its
representative to such information in such records as may be required for Tanabe
to comply with its obligations in this Section 8.2 and in Section 8.3. The
records to be maintained by Tanabe under this Section 8.2 shall be maintained
for a minimum of five (5) years following the date in which the corresponding
efforts or payments, as the case may be, were made under this Agreement, or
longer if required by law.

            8.3   AUDIT REQUEST. Genelabs shall, at its expense (except as
provided below), have the right to audit, on an annual basis, the records
maintained by Tanabe under Section 8.2 in order to determine, with respect to
any payments made to Genelabs by or for Tanabe under Article 6. If Genelabs
desires to audit such records, it shall engage an independent accountant
reasonably acceptable to Tanabe to examine such records during normal business
hours; provided, however, that such right to audit shall be exercised only on at
least ten (10) business days advance written notice, shall not occur more than
once in any twelve (12) month period and not more than once per year in the five
(5) years following termination or expiration of this Agreement (with such audit
rights expiring upon the fifth anniversary of the end of each year subject to
such audit). Such accountant shall, prior to the audit, enter into a
confidentiality agreement with Tanabe prohibiting the auditor from disclosing or
using information obtained in connection with the audit, provided however that
the accountant shall be permitted to provide to Genelabs a report on the
findings of the agreed upon procedures verifying any report made or payment
submitted by Tanabe during such period. The expense of such audit shall be borne
by Genelabs; provided, however, that if an underpayment by Tanabe of more than
five percent (5%) for any payment due under Article 6 is discovered, then such
expenses shall be paid by Tanabe. Any information received by Genelabs pursuant
to this Section 8.3 shall be deemed to be Tanabe Confidential Information.

            8.4   SURVIVAL. This Article 8 shall survive any termination of this
Agreement for a period of five (5) years.

9.    PATENTS.

            9.1   OWNERSHIP OF INVENTIONS.

                  (a)   All Results, Improvements, Technology or other
discoveries acquired, invented, developed, created or conceived by employees,
consultants or Third Party contractors of a party in connection with its
activities under this Agreement ("Sole Inventions") shall be the property of
such party. In the event that at least one employee, consultant or Third Party
contractor of each of Tanabe and Genelabs jointly invent, develop, create or
conceive any Results, Improvements, Technology or other discoveries in the
performance of this Agreement, Tanabe and Genelabs shall each own an undivided
one-half (1/2) interest in, to and under such invention ("Joint Invention") and
all rights therein, thereunder and thereto (including any Patents claiming such
Joint Inventions), without a duty of accounting to, or the requirement of
obtaining consent for licensing or exploitation of such Joint Inventions from,
the other party (subject to the licenses expressly granted herein). Inventorship
shall be determined in accordance with U.S. patent law.

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

                  (b)   Each party shall ensure (and hereby covenants) that all
employees and other persons acting on behalf of such party in performance of
obligations under this Agreement (including without limitation consultants and
Third Party subcontractors) shall be obligated under a binding written agreement
to (i) assign to such party all inventions invented, developed, created or
conceived by such employee or other person in the course of performance of this
Agreement, and (ii) preserve the proprietary and confidential nature of
Confidential Information substantially to the extent provided for in Article 13
(Confidential Information).

            9.2   SOLE PARTY PATENT FILINGS. Each party shall have sole
discretion and responsibility to prepare, file, prosecute and maintain Patents
for Sole Inventions made by such party under this Agreement and shall be
responsible for related interference proceedings which may be performed at its
sole discretion. Each party shall use reasonable efforts to file and prosecute
claims in such Patents specifically directed to the use of Prasterone Products
in the Field and licensed to the other party under this Agreement.

            9.3   JOINT PATENT FILINGS. The JSC shall determine which party
shall be responsible (the "Responsible Party") for filing, prosecuting and
maintaining Joint Patents based on the following principle: Tanabe shall be
responsible for filing, prosecuting and maintaining Joint Patents in the
Territory and Genelabs shall be responsible for filing, prosecuting and
maintaining Joint Patents outside of the Territory. Each party shall provide the
other with reasonable cooperation and assistance in the filing, prosecution and
maintenance of Joint Patents. At least twenty (20) days prior to the
contemplated filing or as soon as reasonably practicable, the Responsible Party
shall submit a substantially completed draft of the Joint Patent application to
the other party for its approval, which shall not be unreasonably withheld.
Except as set forth below, the parties shall bear the costs of the preparation,
filing, prosecution and maintenance of all Joint Patent in which it is
responsible for filing pursuant to this Section 9.3. If the Responsible Party
decides not to file, prosecute or maintain any Joint Patent or maintain such
Joint Patent in a particular country, such Responsible Party shall promptly
provide notice to the other party of such decision and shall promptly grant the
other party any necessary authority to file, prosecute and maintain such Joint
Patent application or maintain such Joint Patent in the name of both parties. If
either party decides not to pay its portion of any shared costs for a Joint
Patent (a "Rejected Patent"), such party shall promptly provide notice to the
other party of such decision and the other party may proceed with such Rejected
Patent in its own name and at its sole expense, in which case the party electing
not to pay its share of costs shall assign its entire right, title and interest
in and to such Rejected Patent to the other party and the invention of such
Rejected Patent shall be treated as a Sole Invention of the assignee under
Section 9.2.

            9.4   IMPROVEMENTS.

                  (a)   GENELABS IMPROVEMENTS. In the event that Genelabs
invents, develops, creates or conceives of any Genelabs Improvements (or such
Genelabs Improvements are made on Genelabs' behalf), Genelabs shall give prompt
written notice to Tanabe describing such Genelabs Improvements in reasonable
detail and such Genelabs Improvements shall be automatically included within the
license grant to Tanabe set forth in Section 3.1 and subject to the terms and
conditions of this Agreement.

                  (b)   TANABE IMPROVEMENTS. In the event that Tanabe, its
Affiliates and/or Tanabe Sublicensees invent, develop, create or conceive of any
Tanabe Improvements (or such Tanabe Improvements are made by Third Party
contractors on their behalf), Tanabe shall give prompt written notice to
Genelabs describing such Tanabe Improvements in reasonable detail and prompt
written notice of any Tanabe Improvement Patents filed with respect thereto.
With respect to intellectual property and proprietary rights (excluding patent
rights and trademark rights) in, to and under Tanabe Improvements,

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

Tanabe hereby grants to Genelabs a fully sublicensable, exclusive royalty-free
license under such rights in, to and under non- patented Tanabe Improvements to
develop, make, have made, use, sell, offer for sale and import Prasterone
Product in the Field on a world-wide basis except in the Territory. Such license
shall be immediately effective upon the giving of such notice by Tanabe of such
non-patentable Tanabe Improvement or, if no such notice is given, the date of
the invention, development, creation or conception of such non-patentable Tanabe
Improvement. With respect to any patented Tanabe Improvements (i.e., rights in,
to and under any Tanabe Improvement Patents), Genelabs shall provide written
notice to Tanabe if Genelabs elects to license such patent rights in, to and
under such Tanabe Improvement from Tanabe within six (6) months of receiving
such notice. If Genelabs so elects, Tanabe agrees to grant and hereby grants to
Genelabs a fully sublicensable, exclusive, royalty-bearing license under Tanabe
Improvement Patents to develop, make, have made, use, sell, offer for sale and
import Prasterone Product in the Field on a world-wide basis except in the
Territory, such license to be subject to mutually agreed upon reasonable terms
and conditions negotiated by the parties in good faith and effective upon
Genelabs' giving of notice of its intention to license such Tanabe Improvement
Patents. Prior to the expiration of the foregoing six (6) month option period,
Tanabe shall not license or otherwise encumber such Tanabe Improvement Patents.

            9.5   EXTENSION OF PATENTS. In the event that Applicable Law in the
Territory provides for the extension of the term of any Genelabs Patents and/or
Genelabs Improvement Patents, Genelabs shall apply, at its own expense for, and
use its reasonable efforts to obtain, such an extension and Tanabe agrees to
co-operate with Genelabs in obtaining such extension. In the event that
Applicable Law in the Territory provides for the extension of the term of any
Joint Patents, Tanabe shall apply, at its own expense for, and use its
reasonable efforts to obtain, such an extension and Genelabs agrees to
co-operate with Tanabe in obtaining such extension.

10.   INFRINGEMENT AND ENFORCEMENT.

            10.1  INFRINGEMENT OF THIRD PARTY RIGHTS.

                  (a)   NOTICE. If Tanabe's sale of Tanabe Products in the
Territory results in a claim that such activity infringes or misappropriates the
patent rights or other intellectual property rights of a Third Party ("Tanabe
Product Infringement"), the party to this Agreement first having notice shall
promptly notify the other party in writing. The notice shall set forth the facts
of the claim in reasonable detail.

                  (b)   DEFENSE BY GENELABS. Subject to Section 10.1(a),
Genelabs shall, at its sole expense, defend such claims of Tanabe Product
Infringement and Tanabe shall provide such assistance and cooperation to
Genelabs as may be necessary to successfully defend any such claim or proceeding
at Genelabs' expense and may be reimbursed of all the expenses related thereto.
Genelabs may not settle any such claim without Tanabe's prior approval if such
settlement would materially and adversely affect Tanabe's interests under this
Agreement.

                  (c)   EXCLUSIONS. Notwithstanding the language in Sections
10.1(a) and (b), Genelabs shall have no obligation to defend Tanabe under this
Section 10.1 if such claim or proceeding relates to or arises from (i) actions,
activities or omissions of or for Tanabe other than the sale by Tanabe of Tanabe
Products in the Territory, (ii) the manufacturing (including formulation,
finishing and/or packaging) of Tanabe Products by or for Tanabe, (iii)
formulations of or components or modifications to Tanabe Products which have
been developed, designed or manufactured by Tanabe, (iv) the combination of the
API or Prasterone Product supplied by Genelabs to Tanabe hereunder with any
ingredients or components, where such combination is the basis for such claim or
proceeding or (v) the manufacturing (including formulation, finishing and/or
packaging), use, marketing and/or sale of Tanabe Products by or

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

for Tanabe for any indications other than for a SLE indication or other
indications of a Tanabe Product covered by Genelabs Patents, Genelabs
Improvement Patents or Joint Patents. If a claim is brought against Tanabe based
upon any of the foregoing, Tanabe shall defend such claims or proceedings at its
sole discretion and at its sole expense.

                  (d)   THIRD PARTY ROYALTIES. If Genelabs is required to make
any payment (including, but not limited to, royalties or other license fees) to
a Third Party to obtain a license or similar right to resolve a claim of Tanabe
Product Infringement, or otherwise secure the right of Tanabe to manufacture,
use or sell Tanabe Products in the Territory without infringing or
misappropriating the intellectual property rights of Third Parties, for any
indication other than for a SLE indication ("Third Party Royalty"), Genelabs
shall have the right to pass through to Tanabe, and, if Tanabe elects to receive
such rights, Tanabe agrees to pay, that portion of such Third Party Royalty
directly attributable to Tanabe's manufacture, use and/or sale of Tanabe
Products in the Territory.

            10.2  INFRINGEMENT BY THIRD PARTIES.

                  (a)   NOTICE. If any of the Joint Patents, Genelabs Patents or
Genelabs Improvement Patents licensed to Tanabe hereunder is infringed in the
Territory by a Third Party product which competes with, or reduces the market
value of, a Tanabe Product in the Field in the Territory (a "Third Party
Infringement"), the party first having knowledge of such infringement shall
promptly notify the other party in writing. The notice shall set forth the facts
of such infringement in reasonable detail.

                  (b)   ENFORCEMENT. Genelabs may at its sole discretion and at
its sole expense, prosecute the judicial or administrative proceedings against
such Third Party Infringement. Tanabe shall provide such assistance and
cooperation to Genelabs as may be reasonably requested to successfully prosecute
any action against Third Party Infringement (including agreeing to be named as a
party in such proceedings) and Genelabs agrees to reimburse Tanabe for all
reasonable expenses incurred by Tanabe as a result of such assistance and
cooperation. Any award in such action shall first be used to reimburse the
parties for their unreimbursed expenses actually incurred under this Section
10.2(b), and the remainder of such award shall be shared equally between the
parties. In the event Genelabs fails to take any action to institute proceedings
to terminate such Third Party infringement, within one hundred eighty (180) days
after notice provided under Section 10.2(a), Tanabe may, in its sole discretion,
take such action as it deems appropriate, including without limitation, the
filing of a lawsuit against such Third Party. In such event Genelabs will
provide such assistance and cooperation to Tanabe as may be reasonably
requested. Any award in such action shall first be used to reimburse the parties
for their unreimbursed expenses actually incurred under this Section 10.2(b) and
the remainder of such award shall be retained by Tanabe and treated as Net Sales
with royalties thereon due and owing to Genelabs.

            10.3  INFRINGEMENT OF JOINT PATENTS.

                  (a)   NOTICE. If any of the Joint Patents, which excludes
Rejected Patents, is infringed by a Third Party product, the party first having
knowledge of such infringement shall promptly notify the other party in writing.
The notice shall set forth the facts of such infringement in reasonable detail.

                  (b)   ENFORCEMENT OUTSIDE THE TERRITORY. Genelabs shall have
the right, but not the obligation, to prosecute, at its own expense, any
judicial or administrative proceedings against such Third Party for such
infringement outside the Territory. Tanabe shall provide such assistance and
cooperation to Genelabs as may be reasonably requested to successfully prosecute
any action against such Third Party (including agreeing to be named as a party
in such proceedings). Any award in such action shall be retained by Genelabs. If
Genelabs fails to initiate any judicial or administrative proceedings against
such

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

Third Party to terminate such infringement within ninety (90) days after
receiving or issuing notice pursuant to Section 10.3(a), Tanabe shall have the
right, but not the obligation, to bring such proceedings at its own expense. In
such event, Genelabs will provide such assistance and cooperation to Tanabe as
may be reasonably requested. Any award in such action brought by Tanabe shall be
retained by Tanabe.

                  (c)   ENFORCEMENT INSIDE THE TERRITORY. Subject to Section
10.2, Tanabe shall have the right, but not the obligation, to prosecute, at its
own expense, any judicial or administrative proceedings against such Third Party
for such infringement inside the Territory. Genelabs shall provide such
assistance and cooperation to Tanabe as may be reasonably requested to
successfully prosecute any action against such Third Party (including agreeing
to be named as a party in such proceedings). Any award in such action shall be
retained by Tanabe. If Tanabe fails to initiate any judicial or administrative
proceedings against such Third Party to terminate such infringement within
ninety (90) days after receiving or issuing notice pursuant to Section 10.3(a),
Genelabs shall have the right, but not the obligation, to bring such proceedings
at its own expense. In such event, Tanabe will provide such assistance and
cooperation to Genelabs as may be reasonably requested. Any award in such action
brought by Genelabs shall be retained by Genelabs.

11.   REPRESENTATIONS, WARRANTIES AND COVENANTS.

            11.1  Each of Genelabs and Tanabe hereby represents, warrants and
covenants to the other party the following:

                  (a)   It is a corporation duly organized and validly existing
and in good standing under the laws of the jurisdiction of its incorporation,
and in each state where a failure to be in good standing would have a material
adverse effect on the operations of such party.

                  (b)   To the best of its knowledge, it has sufficient legal
and/or beneficial title under its intellectual property rights, or sufficient
rights licensed from Third Parties, to grant the rights and licenses provided
hereunder.

                  (c)   All of its Affiliates, employees, officers, Third Party
contractors and consultants (and, solely with respect to Tanabe, Tanabe
Sublicensees) have executed agreements requiring assignment to the party of all
inventions made during the course of and as a result of their association with
such party and obligating the individual to maintain as confidential the
Confidential Information of such party; except where any failure by a party to
obtain such agreements would not have a materially adverse impact on the rights
and licenses granted to the other party under this Agreement.

                  (d)   To the best of its knowledge, it has all necessary
right, power and authority to enter into this Agreement and the performance of
its obligations hereunder will not violate any other agreement to which it is a
party.

                  (e)   It has taken all corporate action necessary to authorize
the execution and delivery of this Agreement.

                  (f)   It has not entered, nor shall it enter, into any
agreement or arrangement with a Third Party that is in conflict with the rights
granted to the other party under this Agreement.

            11.2  Genelabs represents and warrants to Tanabe the following that,
as of the Effective Date:

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

                  (a)   it owns or controls all rights, title and interest in
and to the Genelabs Patents and Genelabs Know-How, that it has full right and
authority to license the rights granted to Tanabe hereunder and that, to the
best of its knowledge without actual investigation, each patent within the
Genelabs Patents is valid and enforceable.

                  (b)   it owns or possesses all right, title and interest in
and to the Genelabs Patents and the Genelabs Know-How free and clear of all
encumbrances, and has the right to convey to Tanabe, in accordance with this
Agreement, the unencumbered licenses set forth herein. Genelabs warrants and
represents as of the Effective Date that it and its Affiliates have not granted
any interest in Genelabs Patents or Genelabs Know-How, are not party to any
agreement (written or oral) or any other arrangement and/or not subject to any
order, judgment or decision from any competent governmental authority, in all
cases which would conflict with this Agreement or the rights granted herein.

                  (c)   to the best of its knowledge without actual
investigation, no intellectual property rights of Genelabs licensed to Tanabe
under this Agreement (including, without limitation, the Genelabs Know- How and
Genelabs Patents) are being infringed by any Third Party.

                  (d)   to the best of its knowledge without actual
investigation, the practice of Genelabs Patents and Genelabs Know- How by Tanabe
in accordance with and as contemplated by the parties in this Agreement in the
Territory does not infringe the patent rights of any Third Party.

                  (e)   to the best of its knowledge without actual
investigation, it has made available to Tanabe all material negative information
in its control as of the Effective Date that may reasonably be expected to have
a material adverse effect on: (i) Genelabs' clinical development program for the
Prasterone Product for SLE indications or (ii) the manufacture or supply of API
or Prasterone Product for SLE indications by or for Genelabs.

                  (f)   The paper copies of the NDA No. 21-239 and EMEA/H/C/531
made available to Tanabe prior to the Effective Date are true and correct copies
of the NDA No. 21-239 and EMEA/H/C/531, respectively, filed by or for Genelabs
with the FDA and the EMEA, respectively.

            11.3  Tanabe represents and warrants to Genelabs the following:

                  (a)   Without limiting any of Tanabe's obligations set forth
in Sections 5.1 and 5.2, Tanabe shall use its best efforts to calculate and
provide sales forecasts in each Commercialization Plan which represent Tanabe's
diligent, good faith and commercially reasonable estimates of projected sales of
Tanabe Products, consistent with the goal of maximizing Net Sales of Tanabe
Products.

            11.4  DISCLAIMER OF WARRANTIES. EXCEPT AS EXPRESSLY PROVIDED FOR IN
THIS AGREEMENT, NEITHER PARTY MAKES, AND EACH PARTY HEREBY DISCLAIMS, ANY AND
ALL REPRESENTATIONS AND WARRANTIES OF ANY KIND, EXPRESS OR IMPLIED, WITH RESPECT
TO THE SUBJECT MATTER OF THIS AGREEMENT, INCLUDING WITHOUT LIMITATION,
WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND
NON-INFRINGEMENT AND ANY WARRANTY ARISING OUT OF PRIOR COURSE OF DEALING AND
USAGE OF TRADE.

12.   MUTUAL INDEMNIFICATION; LIMITATION OF LIABILITY.

            12.1  TANABE'S INDEMNIFICATION OBLIGATION. Tanabe shall indemnify,
defend and hold harmless each of Genelabs, its Affiliates, successors and
assigns and their respective sublicensees,

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

directors, officers, employees and agents from and against any and all
liabilities, damages, losses, settlements, penalties, fines, costs and expenses,
including, without limitation, reasonable attorneys' fees (any of the foregoing
to be referred to herein as "Damages") of whatever kind or nature (but not
including taxes), to the extent arising from any Third Party claim, action, suit
or proceeding (but excluding claims otherwise covered under Section 10.1) based
on: (a) the manufacture, use, sale, offer to sell, import or promotion of Tanabe
Products by or for Tanabe, its Affiliates and/or Tanabe Sublicensees in the
Territory (except if such Damages arises as a result of claims listed in
following (i) through (vii) of this Section 12.01); (b) the negligence or
intentional misconduct of Tanabe or any of its agents or employees; (c) breach
by Tanabe of any term of this Agreement; or (d) any misrepresentation by Tanabe
under Article 11 (all such claims listed above in (a) through (d) collectively
to be referred to as "Genelabs Claims"), in each case except to the extent
attributable to: (i) the negligence or intentional misconduct of Genelabs or any
of its agents or employees; (ii) a material breach by Genelabs of any term of
this Agreement; (iii) the failure of Genelabs to manufacture or supply API or
Prasterone Product in compliance with cGMP or other Applicable Laws; (iv) any
misrepresentation by Genelabs under Article 11; (v) a manufacturing defect in
the API or Prasterone Product as provided by Genelabs or its agents to Tanabe
under this Agreement, or (vi) any other action for which Genelabs is responsible
under Section 12.2.

            12.2  GENELABS' INDEMNIFICATION OBLIGATION. Genelabs shall
indemnify, defend and hold harmless each of Tanabe, its Affiliates, successors
and assigns and their respective sublicensees, directors, officers, employees
and agents from and against any and all Damages of whatever kind or nature (but
not including taxes), to the extent arising from any Third Party claim, action,
suit or proceeding (but excluding claims otherwise covered under Section 10.1)
based on: (a) manufacturing defects in the API or Prasterone Product as provided
to Tanabe by Genelabs or its agents under this Agreement; (b) any defect in the
design of the Prasterone Product as provided to Tanabe by Genelabs or its agents
under this Agreement, (c) the negligence or intentional misconduct of Genelabs
or any or its employees or agents in the performance of its obligations
hereunder; (d) the breach by Genelabs of any term of this Agreement; (e) the
failure of Genelabs to manufacture or supply API hereunder in compliance with
cGMP or any other Applicable Laws; or (f) any misrepresentation by Genelabs
under Article 11 (all such claims listed above in (a) through (f) collectively
to be referred to as, "Tanabe Claims"), in each case except to the extent
attributable to: (i) the negligence or intentional misconduct of Tanabe or any
or its agents or employees; (ii) a material breach by Tanabe of any term of this
Agreement; (iii) any misrepresentation by Tanabe under Article 11; (iv) the
marketing or promotion of Tanabe Products by or for Tanabe (except if such
Damages arise as a result of Tanabe Claims); or (v) any action for which Tanabe
is responsible under Section 12.1.

            For purposes of clause (b) above, a design defect shall not be
deemed to exist if either (x) such defect or the facts or circumstances giving
rise to the Damages for which indemnification is sought has been described in
the scientific literature or art, or (y) Genelabs, its Affiliates and/or its
Third Party contractors have notified Tanabe of such defect or such facts or
circumstances, in either case as of the date the action alleging such defect has
been filed. In the event that a design defect is deemed to exist under the terms
of the preceding sentence (a "Compensable Claim"), then the following shall
apply:

            (I) notwithstanding Section 12.3 below, the Parties shall conduct a
joint defense of the action with each Party bearing its own costs and expenses
incurred in connection therewith;

            (II) neither Party shall settle such action without the prior
written consent of the other Party, not to be unreasonably withheld or delayed;

            (III) any settlement amounts agreed to by the Parties or amounts
paid pursuant to a final judgment by a court of competent authority in an
unappealed or unappealable decision (it being

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

understood and agreed that neither Party shall be required to bring an appeal)
shall be shared equally by the Parties (subject to clause (IV) below); and

            (IV) Genelabs shall not be required to pay any amounts pursuant to
clause (III) above, in the aggregate with respect to all Compensable Claims, in
excess of (A) in the event that Genelabs has obtained insurance coverage
applicable to such Compensable Claim, the maximum coverage limits of such
insurance policy or (B) in the event that Genelabs has not obtained such
insurance (it being understood and agreed that Genelabs will use reasonable
efforts to obtain such insurance), the aggregate amounts received by Genelabs
hereunder pursuant to Sections 6.1(a), 6.2 and 6.3 through the date of payments
made pursuant to clause (III) above.

            12.3  PROCESS FOR INDEMNIFICATION. For purposes of Sections 12.1 and
12.2, the indemnified party shall give prompt written notice to the indemnifying
party of any suits, claims, actions, proceedings or demands by Third Parties
that may give rise to a claim for which indemnification may be required under
this Article 12; provided, however, that failure to give such notice shall not
relieve the indemnifying party of its obligation to provide indemnification
hereunder except, if and to the extent that such failure materially and
adversely affects the ability of the indemnifying party to defend or mitigate
the applicable suit, claim, action, proceeding or demand. The indemnifying party
shall be entitled to assume the defense and control of any such suit, claim,
action proceeding or demand at its own cost and expense; provided, however, that
the other party shall have the right to be represented by its own counsel at its
own cost in such matters. Neither the indemnifying party nor the indemnified
party shall settle or dispose of any such matter in any manner that would
materially and adversely affect the rights or interests of the other party
(including the obligation to indemnify hereunder) without the prior written
consent of the other party, which shall not be unreasonably withheld or delayed.
Each party shall cooperate with the other party and its counsel in the course of
the defense of any such suit, claim, action, proceeding or demand, such
cooperation to include, without limitation, using reasonable efforts to provide
or make available documents, information and witnesses.

            12.4  LIMITATION OF LIABILITY. IN NO EVENT WILL EITHER PARTY BE
LIABLE TO THE OTHER FOR ANY SPECIAL, INCIDENTAL, CONSEQUENTIAL, LOST PROFITS OR
INDIRECT DAMAGES OF SUCH OTHER PARTY OF ANY KIND ARISING IN ANY WAY OUT OF THIS
AGREEMENT, HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY. NOTWITHSTANDING ANY
FAILURE OF ESSENTIAL PURPOSE OF ANY LIMITED WARRANTY PROVIDED HEREIN, THIS
LIMITATION WILL APPLY EVEN IF THE OTHER PARTY HAS BEEN ADVISED OF THE
POSSIBILITY OF SUCH DAMAGE. THE FOREGOING LIMITATION SHALL NOT APPLY, HOWEVER,
TO THE CONFIDENTIALITY OBLIGATIONS UNDER ARTICLE 13 OR TO ACTIONS BY A PARTY
AGAINST THE OTHER PARTY FOR PATENT INFRINGEMENT OR MISAPPROPRIATION OF TRADE
SECRETS OR OTHER ACTS OUTSIDE OF THE AGREEMENT OR in circumstances where such
damages have arisen due to fraud or intentional misrepresentation by such OTHER
Party.

13.   CONFIDENTIALITY.

            13.1  CONFIDENTIAL DISCLOSURE AGREEMENT. The parties entered into a
confidential disclosure agreement dated as of September 5, 2002 ("Confidential
Disclosure Agreement"). Upon execution of this Agreement, the Confidential
Disclosure Agreement shall be replaced and superceded by the confidentiality
provisions set forth in this Agreement with respect to any information disclosed
or used hereunder; provided, however, that such Confidential Disclosure
Agreement shall remain in full force and effect, in accordance with its terms,
with respect to information disclosed prior to the Effective Date (and

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

with respect to information that is not disclosed or used hereunder) and acts or
omissions of the parties with respect thereto. For the avoidance of doubt, the
terms and conditions of this Article 13 shall apply to information otherwise
qualifying as Confidential Information (as defined in Section 13.2 below) that
was already disclosed under the Confidential Disclosure Agreement prior to the
Effective Date to the extent such information is used by the receiving party
under this Agreement.

            13.2  CONFIDENTIALITY; EXCEPTIONS. In connection with this
Agreement, the parties may provide to each other Confidential Information,
including but not limited to each party's know-how, invention disclosures,
proprietary materials and/or technologies, economic information, business or
research strategies, trade secrets and material embodiments thereof. As used
herein, "Confidential Information" means any information of a confidential or
proprietary nature disclosed by a party to the other party. For the avoidance of
doubt, the regulatory materials provided by Genelabs to Tanabe pursuant to
Section 2.4 (NDA No. 21-239 and EMEA/H/C/531) and through the right of reference
granted to Tanabe pursuant to Section 4.2(a), all Tanabe Clinical Data and all
Genelabs Clinical Data shall be deemed to be Confidential Information of the
disclosing party hereunder. Notwithstanding the foregoing, Confidential
Information of a disclosing party shall not include:

                  (a)   information which, at the time of disclosure to the
receiving party by or for the disclosing party, was previously known to the
receiving party as demonstrated by contemporaneous written records;

                  (b)   information which, at the time of disclosure to the
receiving party by or for the disclosing party, is published or otherwise
generally available to the public;

                  (c)   information which, after disclosure to the receiving
party by or for the disclosing party, is published or otherwise becomes
generally available to the public through no breach of this Agreement by the
receiving party;

                  (d)   information which is received by the receiving party
from a Third Party which did not directly or indirectly receive the information
from the disclosing party, and which Third Party has the legal right to disclose
the same and which is not required to hold the same confidential;

                  (e)   information that is independently developed by the
receiving party without use of, application of or reference to the disclosing
party's Confidential Information; and

                  (f)   information concerning the tax treatment and tax
structure of the transactions contemplated by this Agreement and all materials
of any kind (including opinions or other tax analyses) that are provided to the
receiving party relating to such tax treatment and tax structure.

            13.3  CONFIDENTIALITY OBLIGATIONS. The recipient of a disclosing
party's Confidential Information shall maintain such Confidential Information in
confidence and shall disclose such Confidential Information only to its
employees, agents, consultants, Affiliates, sublicensees, attorneys, accountants
and advisors who have a reasonable need to know such Confidential Information
and who are bound by obligations of confidentiality and non-use no less
restrictive than those set forth herein. The recipient of the disclosing party's
Confidential Information shall use such Confidential Information solely to
exercise the receiving party's rights and perform the receiving party's
obligations as set forth in this Agreement (including, without limitation, the
right to use and disclose such Confidential Information in regulatory
applications and filings), unless otherwise mutually agreed in writing. The
recipient of the other party's Confidential Information shall take the same
degree of care that it uses to protect its own

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                                             ** CONFIDENTIAL TREATMENT REQUESTED

confidential and proprietary information of a similar nature and importance (but
in any event no less than reasonable care).

            13.4  PERMITTED DISCLOSURE. A receiving party may disclose
Confidential Information of the disclosing party under the following
circumstances, provided that the receiving party has promptly provided prior
written notice to the disclosing party, and shall provide reasonable cooperation
and assistance, to enable the disclosing party to seek a protective order or
otherwise prevent or limit disclosure and/or use of such Confidential
Information of the disclosing party: (a) as required, in connection with the
order of a court or other governmental body; (b) as required by or in compliance
with laws or regulations; (c) as required in the course of obtaining regulatory
and necessary institutional approvals to clinically test, sell or market Tanabe
Products or to perform research and development with respect to Tanabe Products;
and(d) as required to secure patent protection for an invention developed as a
result of the research and development activities undertaken pursuant to this
Agreement.

            13.5  SURVIVAL. This Article 13 shall survive the termination or
expiration of this Agreement for a period of ten (10) years.

14.   PUBLICITY.

            14.1  INITIAL PRESS RELEASE. The parties shall issue a mutually
approved, initial press release within thirty (30) days after the Effective
Date.

            14.2  PUBLIC ANNOUNCEMENTS. With the exception of Section 14.1,
neither Tanabe nor Genelabs shall make any public announcement concerning the
existence of or the terms of this Agreement, without the prior written approval
of the other party with regard to the form, content and precise timing of such
announcement, except and only to the extent that such as may be required to be
made by either party in order to comply with applicable law, regulations, court
order, or tax or securities filings. Such consent shall not be unreasonably
withheld or delayed by such other party. Prior to any such public announcement,
the party wishing to make the announcement will submit a draft of the proposed
announcement to the other party in sufficient time to enable the other party to
consider and comment thereon. Notwithstanding anything to the contrary in this
Agreement: (a) nothing in this Article 14 is intended to prohibit either party
from republishing or restating information relating to this Agreement that has
already been approved by the other party for use in a prior press release or
public announcement, and (b) Tanabe shall be permitted to issue press releases
or public announcements about Tanabe Products without Genelabs' prior written
consent after the Commercial Launch of a Tanabe Product, subject to reasonable
prior notice under the circumstances to Genelabs with respect to significant,
previously undisclosed beneficial or adverse matters concerning Tanabe Products
or a Prasterone Product.

15.   USE OF GENELABS' MARKS AND LOGOS ON PACKAGING; TRADEMARKS.

            15.1  USE OF GENELABS' TRADEMARKS. With respect to the development
and commercialization of Tanabe Products under this Agreement, Tanabe shall have
the choice, at its sole discretion, to (a) develop its own trademarks or (b) use
any of Genelabs trademarks set forth in Exhibit B (the "Trademarks"). Tanabe
shall provide written notice of its election under this Section 15.1 to Genelabs
within eighteen (18) months after the Effective Date.

            15.2  LICENSE OF TRADEMARKS. In the event that Tanabe elects to use
the Trademarks in connection with its development and/or commercialization of
Tanabe Products under this Agreement, Genelabs shall be responsible for the
filing, prosecution, maintenance and defense of Japanese character

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                                       29
<PAGE>

                                             ** CONFIDENTIAL TREATMENT REQUESTED

version (Katakana) of the Trademarks selected by Tanabe, at Tanabe's own
expense. Genelabs will agree to grant to Tanabe an exclusive, royalty-free,
non-transferable (but shall be sublicensable pursuant to and subject to Section
3.2) right and license to use the Trademarks and their Japanese character
version (Katakana) in connection with its marketing and commercialization of
Tanabe Products in the Territory under suitable terms and conditions to preserve
the strength and enforceability of any Trademark. The parties will enter into a
written agreement covering such terms and conditions when and if Tanabe so
elects to use the Trademarks.

            15.3  TANABE TRADEMARKS. In the event that Tanabe elects to develop
its own trademarks ("Tanabe Trademarks") in connection with the development and
commercialization of Tanabe Products under this Agreement, Tanabe shall be
responsible for the filing, prosecution, maintenance and defense of such
trademarks and their Japanese character version (Katakana). In the event of
termination of this Agreement by Tanabe pursuant to Section 16.3 or by Genelabs
pursuant to Section 16.4, Tanabe shall assign any such Tanabe Trademark to
Genelabs under terms and conditions drafted to preserve the strength and
enforceability of such trademark, as mutually agreed by the parties in writing.

16.   TERM AND TERMINATION.

            16.1  TERM. The term of this Agreement shall commence as of the
Effective Date and, unless sooner terminated in whole or in part as specifically
provided for in this Agreement, shall continue in effect until termination of
Tanabe's royalty obligations under Section 6.9. After the expiration of the term
in accordance with the foregoing (unless earlier terminated), Tanabe licenses
under Genelabs' rights in, to and under Genelabs Know-How, Genelabs Clinical
Data and Trademarks (subject to Article 15) to make, have made, use, sell, offer
for sale and import Tanabe Products in the Territory shall become royalty-free;
provided however that Tanabe may still be subject to the terms and conditions of
Genelabs' agreements with Third Parties and/or Genelabs Licensees as provided
for in this Agreement.

            16.2  TERMINATION FOR DEFAULT. If either party materially breaches
any material term or condition of this Agreement, the other party may notify the
breaching party in writing of such breach, setting forth the nature of the
breach in reasonable detail. If the breaching party fails to cure such breach
within sixty (60) days after the receipt of the foregoing notice from the
non-breaching party for any and all material breaches, then the non-breaching
party may terminate this Agreement effective immediately upon a second written
notice to the breaching party.

            16.3  VOLUNTARY TERMINATION. Prior to the commercial launch of the
first Tanabe Product, Tanabe shall have the right to terminate this Agreement,
with or without cause, upon one hundred eighty (180) days prior written notice
to Genelabs. Following the commercial launch of the first Tanabe Product, Tanabe
shall have the right to terminate this Agreement, with or without cause, upon
three hundred sixty-five (365) days prior written notice to Genelabs; provided
however that Tanabe shall provide commercially reasonable support to Genelabs to
ensure a smooth transition of responsibilities to Genelabs' new partner in the
Territory, including without limitation by providing reasonable copies of
documents and materials reasonably requested by Genelabs and to answer
reasonable questions and provide reasonable advice which relate to the Tanabe
Product.

            16.4  TERMINATION FOR REASONS OF INSOLVENCY OR TERMINATION OF
BUSINESS ACTIVITIES. Either party may forthwith terminate this Agreement by
giving a written notice of termination to the other party, if the other party
makes a general assignment for the benefit of creditors; applies for or consents
to the appointment of a receiver, trustee or liquidator for substantially all of
its assets or such a receiver, trustee or liquidator is appointed; or such other
party has filed against it an involuntary petition of bankruptcy that has not
been dismissed within thirty (30) days thereof, or files a voluntary petition of
bankruptcy, or a

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                                       30
<PAGE>

                                             ** CONFIDENTIAL TREATMENT REQUESTED

petition or answer seeking reorganization, or seeks to take advantage of any
other law relating to relief of debtors; or has wound up or liquidated its
business.

            16.5  SURVIVING OBLIGATIONS. Termination or expiration of this
Agreement shall not terminate Tanabe's obligation to pay all milestone payments,
royalties and other payments that shall have accrued hereunder prior to the date
of such expiration or termination. In the event Tanabe terminates this Agreement
pursuant to Section 16.3, the obligations of the parties under Sections 2.4
(with respect to Tanabe's obligation to provide information), 2.7, 3.3, 3.4,
4.2(c), 5.3, 5.5 (for as long as the parties have Prasterone Products in the
market), 9.1(a), 9.3, 9.4(b), 10.3, 15.3 and 16.5-7 and Articles 8, 12-13 and
17-18 of this Agreement shall survive the termination of this Agreement. In the
event of any other termination or expiration of the Agreement, the obligations
of the parties under Sections 2.4, 2.5, 2.7, 3.3, 3.4, 4.2 (excluding however
the parties' obligation to provide assistance and cooperation to each other in
connection with the other party's regulatory filings), 4.3, 5.3, 5.5 (for as
long as the parties have Prasterone Products in the market), 9.1, 9.2, 9.3,
10.3, 15.3 and 16.5-7 and Articles 8, 12-13 and 17-18 of this Agreement shall
survive the termination or expiration of this Agreement.

            16.6  CONTINUING LIABILITY. Termination or expiration of this
Agreement for any reason shall not release any party from any liability or
obligation that already has accrued prior to such expiration or termination, nor
affect the survival of any provision hereof to the extent it is expressly stated
to survive such termination. Termination of this Agreement for any reason shall
not constitute a waiver or release of, or otherwise be deemed to prejudice or
adversely affect, any rights, remedies or claims, whether for damages or
otherwise, that a party may have hereunder or that may arise out of or in
connection with such termination.

            16.7  DESTRUCTION OF CONFIDENTIAL INFORMATION. Within thirty (30)
days after the expiration or earlier termination of this Agreement, each party
shall destroy the Confidential Information of the other party disclosed under
this Agreement, such destruction to be confirmed in writing to such other party
by the destroying party; provided however that either party may retain the other
party's Confidential Information solely to the extent necessary to exercise its
rights surviving such termination or expiration as set forth under Section 16.5.

17.   DISPUTE RESOLUTION.

            17.1  ARBITRAL BODY MEDIATION.

                  (a)   Any claim or controversy arising out of or related to
this Agreement or any breach hereof that cannot be resolved by the parties or
through the procedure set forth in Section 2.2(c), including disputes relating
to an alleged breach or to termination of this Agreement shall first be
submitted to the parties' respective Chief Executive Officers for attempted
resolution by good faith negotiation within thirty (30) days after such referral
is made. In the event such officers are unable to resolve such dispute within
such thirty (30) day period, either party may assert its rights in a manner in
accordance with the provisions of Section 17.1(b) below.

                  (b)   If the parties are unable to resolve a dispute through
executive mediation as set forth in Section 17.1(a), such dispute shall be
finally and exclusively resolved by arbitration under the then obtaining Rules
of Arbitration of the International Chamber of Commerce, by which each party
hereto agrees to be bound. The arbitration shall consist of a single arbitrator
mutually agreed by the parties, or, in the absence of such agreement, each party
shall select an arbitrator and those two arbitrators shall select a third
arbitrator who shall arbitrate the dispute. Any arbitration shall take place in
San Francisco, California, U.S., if such arbitration is initiated by Tanabe, and
in Osaka, Japan, if such

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                                       31
<PAGE>

                                             ** CONFIDENTIAL TREATMENT REQUESTED

arbitration is initiated by Genelabs. The award of the arbitrator shall be final
and binding. The parties waive any right to appeal the arbitration award, to the
extent a right to appeal may be lawfully waived. Each party retains the right to
seek judicial assistance: (i) to compel arbitration; (ii) to obtain interim
measures of protection such as temporary injunctions or similar equitable relief
pending or during arbitration; and (iii) to enforce any decision of the
arbitrator, including the final award.

                  (c)   The arbitration shall be confidential and the arbitrator
shall take appropriate steps to safeguard each party's Confidential Information.
Except as required by law, no party shall make (or instruct the arbitrator to
make) any public announcement with respect to the proceedings or decision of the
arbitrator without the prior written consent of the other party. The existence
of any dispute submitted to arbitration, and the recommendation of the
arbitrator, shall be kept in confidence by the parties and the arbitrator,
except as otherwise required by Applicable Laws.

                  (d)   The arbitrator in any such dispute shall issue his or
her decision on any issues submitted for resolution under this Section 17.1 in a
reasonably prompt time frame under the circumstances, but in any event no later
than within one hundred twenty (120) days after the arbitrator has been
selected, unless the parties mutually agree otherwise.

18.   MISCELLANEOUS.

            18.1  AGENCY. Neither party is, nor shall it be deemed to be, an
employee, agent, co-venturer, partner or legal representative of the other party
for any purpose. Neither party shall be entitled to enter into any contracts in
the name of, or on behalf of, the other party, nor shall either party be
entitled to pledge the credit of the other party in any way or hold itself out
as having the authority to do so.

            18.2  SUCCESSORS AND ASSIGNS; ASSIGNMENT. The terms and provisions
of this Agreement shall inure to the benefit of, and be binding upon, Tanabe,
Genelabs and their respective successors and permitted assigns; provided,
however, that neither Tanabe nor Genelabs may transfer or assign any of its
rights and obligations hereunder without the prior written consent of the other,
such consent not to be unreasonably withheld, except that either party may
transfer or assign any of its rights and obligations hereunder to a person that
acquires all or substantially all of the assets of such party or pursuant to a
merger or consolidation involving substantially all of the assets to which this
Agreement relates, provided that such assignee or transferee promptly agrees in
writing to be bound by the terms and conditions of this Agreement. Each party
shall notify the other within thirty (30) days after any such transfer,
assignment, merger, sale or consolidation. The party receiving such notices
shall keep such information strictly confidential. Unless affirmed in writing by
the nonassigning party, any purported assignment in contravention of this
Section 18.2 shall be null and void and of no effect.

            18.3  FURTHER ACTIONS. Each party agrees to execute, acknowledge and
deliver such further instruments and to do all such other acts that may be
necessary or appropriate to carry out the purpose and intent of this Agreement.

            18.4  FORCE MAJEURE. Neither party shall be held responsible for any
delay or failure in performance hereunder caused by strikes, embargoes,
unexpected government requirements, civil or military authorities, acts of God,
earthquake, or by the public enemy or other causes reasonably beyond such
party's control and without such party's fault or negligence; provided that the
affected party notifies the unaffected party as soon as reasonably possible, and
resumes performance hereunder as soon as reasonably possible following cessation
of such force majeure event. The party giving such notice shall thereupon be
excused from such of its obligations hereunder as it is thereby disabled from
performing for so long as it is so disabled and the party receiving notice shall
be similarly excused from its respective

License and Collaboration Agreement (Prasterone)

                                       32
<PAGE>

                                             ** CONFIDENTIAL TREATMENT REQUESTED

obligations which it is thereby disabled from performing; provided, however,
that party providing notice commences and continues reasonable and diligent
actions to cure such force majeure cause. Notwithstanding the foregoing, nothing
in this Section 18.4 shall excuse or suspend the obligation to make any payment
due hereunder in the manner and at the time provided.

            18.5  NOTICES. All notices, reports and other communications
hereunder shall be in English, in writing and shall be deemed given if delivered
personally or by facsimile transmission (receipt verified), telexed, mailed by
registered or certified mail (return receipt requested), postage prepaid or sent
by express courier service to the parties at the following addresses (or at such
other address for a party as shall be specified by like notice; provided that,
notices of a change of address shall be effective only upon receipt thereof):

         If to Tanabe,
         addressed to:             Tanabe Seiyaku Co., Ltd.
                                   2-10 Dosho-machi 3-chome,
                                   Chuo-Ku, Osaka, Japan
                                   Fax: +81 6 6202 5040
                                   Attention: General Manager of Legal Division

         If to Genelabs,
         addressed to:             Genelabs Technologies, Inc.
                                   505 Penobscot Drive,
                                   Redwood City, California, United States 94063
                                   Fax: +650-368-0709
                                   Attention:  General Counsel

            18.6  AMENDMENT. No amendment, modification or supplement of any
provision of this Agreement shall be valid or effective unless made in writing
and signed by a duly authorized officer of each party.

            18.7  WAIVER. The failure of a party to enforce any rights or
provisions of the Agreement shall not be construed to be a waiver of such rights
or provisions, or a waiver by such party to thereafter enforce such rights or
provision or any other rights or provisions hereunder. No waiver hereunder shall
be effective unless made in writing and signed by the waiving party.

            18.8  COUNTERPARTS. This Agreement may be executed in two or more
counterparts, each of which shall be deemed an original and all of which
together shall constitute one instrument.

            18.9  DESCRIPTIVE HEADINGS. The article, section and paragraph
headings contained herein are for the purposes of convenience only and are not
intended to define or limit the contents of the articles, sections or paragraphs
to which such headings apply.

            18.10 SEVERABILITY. Whenever possible, each provision of this
Agreement shall be interpreted in such manner as to be effective and valid under
applicable law, but if any provision of this Agreement is held to be prohibited
by or invalid under applicable law, such provision shall be ineffective only to
the extent of such prohibition or invalidity, without invalidating the remainder
of this Agreement. In the event of such invalidity, the parties shall seek to
agree on an alternative enforceable provision that preserves the original
purpose of this Agreement.

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                                       33
<PAGE>

                                             ** CONFIDENTIAL TREATMENT REQUESTED

            18.11 PATENT MARKING. Tanabe agrees to mark the appropriate patent
number or numbers on all Tanabe Products (or the container or label, as
appropriate) made or sold in accordance with all applicable governmental laws,
rules and regulations to the extent reasonably possible, and to require Tanabe
Sublicensees to do the same.

            18.12 GOVERNING LAW. This Agreement shall be governed by and
construed in accordance with the laws of California, without regard to conflicts
of laws principles or provisions that would result in the application of the
substantive laws of another jurisdiction.

            18.13 COMPLIANCE WITH LAW. Nothing in this Agreement shall be deemed
to permit either party to export, re-export or otherwise transfer any Technology
of the other party transferred hereunder or Tanabe Products manufactured
therefrom without complying with applicable laws.

            18.14 ENTIRE AGREEMENT OF THE PARTIES. This Agreement and the
Exhibits attached hereto, constitute and contain the complete, final and
exclusive understanding and agreement of the parties hereto and cancel and
supersede any and all prior negotiations, correspondence, understandings and
agreements, whether oral or written, between the parties respecting the subject
matter hereof (including without limitation the letter of intent dated as of
July 17, 2003 by and between the parties), and no party shall be liable or bound
to any other party in any manner by any representations, warranties, covenants
or agreements, except as specifically set forth herein or therein. Nothing in
this Agreement, express or implied, is intended to confer upon any party, other
than the parties hereto and their respective successors and assigns, any rights,
remedies, obligations or liabilities under or by reason of this Agreement,
except as expressly provided herein.

IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be executed
by their duly authorized representatives, as of the Effective Date.

GENELABS TECHNOLOGIES, INC.                  TANABE SEIYAKU CO., LTD.

By: /s/ IRENE A. CHOW                        By: /s/ N. HAYAMA

Date: 1/28/04                                Date: Jan 28 2004

Name: Irene A. Chow                          Name: Natsuki Hayama

Title: Chairman of the Board and             Title: President and Representative
       Chief Executive Officer                      Director

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                                       34
<PAGE>

                                             ** CONFIDENTIAL TREATMENT REQUESTED

                           EXHIBIT A: GENELABS PATENTS

WO/00/54763

WO/01/35949

WO/0135975

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                                       35
<PAGE>

                                             ** CONFIDENTIAL TREATMENT REQUESTED

                              EXHIBIT B: TRADEMARKS

ANASTAR(R)

      Registered 3/7/03, Renewal due 3/7/08

      Registration number: 4651389

      Description: Pharmaceutical preparations, namely, steroids

PRESTARA(R)

      Registered 7/19/02, Renewal due 7/19/07

      Registration number 4587650

      Description: Pharmaceutical preparations

License and Collaboration Agreement (Prasterone)

                                       36
<PAGE>

                            STOCK PURCHASE AGREEMENT

                                     between

                           GENELABS TECHNOLOGIES, INC.

                                       and

                            TANABE SEIYAKU CO., LTD.

                                   dated as of

                                January 28, 2004

<PAGE>

                            STOCK PURCHASE AGREEMENT

      THIS STOCK PURCHASE AGREEMENT dated as of January 28, 2004 (the
"AGREEMENT") is made between GENELABS TECHNOLOGIES, INC., a California
corporation, ("GENELABS") and TANABE SEIYAKU CO., LTD., a Japanese corporation
("TANABE").

                                 R E C I T A L S

      A.    Genelabs is willing to enter into a License and Collaboration
Agreement with Tanabe for the commercialization of products on the terms and
conditions set forth in the License and Collaboration Agreement of even date
herewith between Genelabs and Tanabe (the "LICENSE AND COLLABORATION
AGREEMENT").

      B.    In connection with the License and Collaboration Agreement, Genelabs
shall sell to Tanabe that number of shares of Genelabs common stock, no par
value (the "COMMON STOCK") equal to two million six hundred thousand dollars
($2,600,000) (the "Purchase Price") divided by the Determined Price per share
(defined below) (the "Purchased Shares"). If the calculation of the number of
Purchased Shares shall result in a fractional share, the number of Purchased
Shares shall be rounded down to the nearest whole share.

      NOW THEREFORE, in consideration of the premises and of the covenants
herein contained, the parties hereto mutually agree as follows:

      1.    Authorization of Sale of the Shares. Subject to the terms and
      conditions of this Agreement, Genelabs has authorized the sale to Tanabe
      of the Purchased Shares.

            (a)   Purchase and Sale. Following the execution and delivery of
this Agreement, Genelabs shall sell to Tanabe, and Tanabe shall purchase from
Genelabs, upon the terms and conditions hereinafter set forth, the Purchased
Shares. For purposes of this Agreement, the Determined Price per share shall be
a price that is 115% of the Market Price per share. The Market Price per share
shall be the average of the closing prices of the Common Stock as quoted on
Nasdaq for the ten-trading-day period ending January 27, 2004. In calculating
the average of the closing prices of the Common Stock, three (3) decimals shall
be effective.

      2.    Deliveries at Closing.

            2.1   Delivery of the Purchased Shares and Purchase Price at the
      Closing. The closing (the "Closing") of the purchase and sale of the
      Purchased Shares shall occur immediately upon Genelabs's receipt of the
      Purchase Price by wire transfer from Tanabe following the execution of
      this Agreement. Upon receipt of the wire transfer of the Purchase Price,
      Genelabs shall deliver to Tanabe via express/overnight courier one or more
      stock certificates representing the Purchased Shares registered in the
      name of Tanabe. Genelabs' obligation to complete the purchase and sale of
      the Purchased Shares

<PAGE>

      at the Closing shall be subject to receipt by Genelabs of a wire transfer
      in the full amount of the Purchase Price for the Purchased Shares and the
      accuracy in all material respects of the representations and warranties
      made by Tanabe herein, except to the extent that Genelabs shall elect to
      waive all or a part of such conditions. Tanabe's obligation to accept
      delivery of such stock certificate(s) and to pay for the Purchased Shares
      shall be subject to the accuracy in all material respects of the
      representations and warranties made by Genelabs herein, except to the
      extent that Tanabe shall elect to waive all or a part of such conditions.

      3.    Representations and Warranties of Genelabs. Except as set forth on
      the Disclosure Schedule attached hereto, Genelabs hereby represents and
      warrants to Tanabe as follows:

            3.1   Organization and Qualification. Genelabs and each of its
      Subsidiaries (each a "SUBSIDIARY" and together the "SUBSIDIARIES") as
      listed on the Disclosure Schedule is an entity duly incorporated or
      otherwise organized, validly existing and in good standing under the laws
      of the jurisdiction of its incorporation or organization (as applicable),
      with the requisite power and authority to own and use its properties and
      assets and to carry on its business as currently conducted. Neither
      Genelabs nor any Subsidiary is in violation of any of the provisions of
      its respective certificate or articles of incorporation, bylaws or other
      organizational or charter documents that could have or could reasonably be
      expected to result in a Material Adverse Effect (as defined below). Each
      of Genelabs and each Subsidiary is duly qualified to conduct business and
      is in good standing as a foreign corporation or other entity in each
      jurisdiction in which the nature of the business conducted or property
      owned by it makes such qualification necessary, except where the failure
      to be so qualified or in good standing, as the case may be, could not,
      individually or in the aggregate, have or reasonably be expected to result
      in a material and adverse effect on the results of operations, business or
      financial condition of Genelabs and the Subsidiaries, taken as a whole (a
      "MATERIAL ADVERSE EFFECT").

            3.2   Authorized Capital Stock. As of the date hereof, the
      authorized capital stock of Genelabs consists of (a) 125,000,000 shares of
      Common Stock, of which on December 31, 86,935,492 shares were validly
      issued and outstanding, fully paid and non-assessable and (b) 4,990,000
      shares of undesignated preferred stock, no par value per share, none of
      which are issued and outstanding. Except for the options and warrants to
      purchase shares of Common Stock listed on the Disclosure Schedule, there
      are not outstanding any options, warrants, rights (including conversion or
      preemptive rights) or agreements for the purchase or acquisition from
      Genelabs of any shares of its capital stock. The Disclosure Schedule also
      lists the number of shares reserved for the exercise of options granted in
      the future.

            3.3   Authorization, Execution and Enforcement. Genelabs has the
      requisite corporate power and authority to enter into and to perform the
      transactions contemplated by this Agreement and otherwise to carry out its
      obligations hereunder. The execution and delivery of this Agreement by
      Genelabs and the consummation by it of the

<PAGE>

      transactions contemplated hereby have been duly authorized by all
      necessary action on the part of Genelabs and no further action is required
      by Genelabs in connection herewith. Upon the execution and delivery of
      this Agreement, this Agreement shall constitute a valid and binding
      obligation of Genelabs enforceable in accordance with its terms, except as
      enforceability may be limited by applicable bankruptcy, insolvency,
      reorganization, moratorium or similar laws affecting creditors' and
      contracting parties' rights generally and except as enforceability may be
      subject to general principles of equity (regardless of whether such
      enforceability is considered in a proceeding in equity or at law).

            3.4   No Conflicts. The execution, delivery and performance of this
      Agreement by Genelabs and the consummation by Genelabs of the transactions
      contemplated hereby do not: (i) conflict with or violate any provision of
      Genelabs' or any Subsidiary's certificate or articles of incorporation,
      bylaws or other organizational or charter documents, or (ii) conflict
      with, or constitute a default (or an event that with notice or lapse of
      time or both would become a default) under, or give to others any rights
      of termination, amendment, acceleration or cancellation (with or without
      notice, lapse of time or both) of, any agreement, credit facility, debt or
      other instrument (evidencing a Genelabs or Subsidiary debt or otherwise)
      or other understanding to which Genelabs or any Subsidiary is a party or
      by which any property or asset of Genelabs or any Subsidiary is bound or
      affected, or (iii) result in a violation of any law, rule, regulation,
      order, judgment, injunction, decree or other restriction of any court or
      governmental authority to which Genelabs or a Subsidiary is subject
      (including federal and state securities laws and regulations), or by which
      any property or asset of Genelabs or a Subsidiary is bound or affected, or
      (iv) result in the creation or imposition of any lien, security interest,
      mortgage, pledge, charge or other encumbrance on any properties or assets
      of Genelabs or any Subsidiary; except in the case of each of clauses (ii)
      and (iii), such as could not, individually or in the aggregate, have or
      reasonably be expected to result in a Material Adverse Effect.

            3.5   Filings, Consents and Approvals. Other than an approval or
      determination under the rules of the NASDAQ National Market that the
      Purchased Shares may be issued without approval of the shareholders of
      Genelabs, Genelabs is not required to obtain any consent, waiver,
      authorization or order of, give any notice to, or make any filing or
      registration with, any court or other federal, state, local or other
      governmental authority or other person in connection with the execution,
      delivery and performance by Genelabs of this Agreement.

            3.6   Issuance of the Purchased Shares. The Purchased Shares have
      been duly authorized and, when issued and paid for in accordance with this
      Agreement, will be duly and validly issued, fully paid and nonassessable,
      free and clear of all liens, charges, encumbrances, security interests,
      rights of first refusal or other restrictions of any kind.

            3.7   SEC Reports; Financial Statements. Genelabs has filed all
      reports required to be filed by it under the Securities Act of 1933, as
      amended (the "SECURITIES ACT"), and

<PAGE>
      the Exchange Act of 1934, as amended (the "EXCHANGE ACT"), including
      pursuant to Section 13(a) or 15(d) thereof, for the thirty-six months
      preceding the date hereof (the foregoing materials being collectively
      referred to herein as the "SEC REPORTS" and, together with the Disclosure
      Schedule, the "DISCLOSURE MATERIALS") or has filed an extension of such
      time of filing and has filed any such SEC Reports prior to the expiration
      of any such extension. As of their respective dates, the SEC Reports
      complied in all material respects with the requirements of the Securities
      Act and the Exchange Act and the rules and regulations of the Securities
      and Exchange Commission (the "Commission") promulgated thereunder, and
      none of the SEC Reports, when filed, contained any untrue statement of a
      material fact or omitted to state a material fact required to be stated
      therein or necessary in order to make the statements therein, in light of
      the circumstances under which they were made, not misleading. The
      financial statements of Genelabs included in the SEC Reports comply in all
      material respects with applicable accounting requirements and the rules
      and regulations of the Commission with respect thereto as in effect at the
      time of filing. Such financial statements have been prepared in accordance
      with generally accepted accounting principles applied on a consistent
      basis during the periods involved ("GAAP"), except as may be otherwise
      specified in such financial statements or the notes thereto, and fairly
      present in all material respects the financial position of Genelabs and
      its consolidated Subsidiaries as of and for the dates thereof and the
      results of operations and cash flows for the periods then ended.

            3.8   Material Changes. Since the date of the latest audited
      financial statements included within the SEC Reports, except as
      specifically disclosed in the SEC Reports, there has been no event,
      occurrence or development that has had or that could reasonably be
      expected to result in a Material Adverse Effect.

            3.9   Certain Fees. No brokerage or finder's fees or commissions are
      or will be payable by Genelabs to any broker, financial advisor or
      consultant finder, placement agent, investment banker, bank or other
      person with respect to the transactions contemplated by this Agreement.
      Tanabe shall have no obligation with respect to any fees or with respect
      to any claims (other than such fees or commissions owed by Tanabe pursuant
      to agreements executed or entered into by Tanabe which fees or commissions
      shall be the sole responsibility of Tanabe) made by or on behalf of other
      persons for fees of a type contemplated in this Section that may be due in
      connection with the transactions contemplated by this Agreement.

            3.10  Securities Law Compliance. Assuming the accuracy of the
      representations and warranties of Tanabe contained in Section 5, the
      offer, issuance, sale and delivery of the Securities constitute an exempt
      transaction under the Securities Act.

            3.11  Registration Rights. Except as contemplated by Section 6 of
      this Agreement or disclosed in the Disclosure Schedule, Genelabs is
      currently not under any obligation to register any of its securities.

<PAGE>
      4.    Representations, Warranties and Covenants of Tanabe. Tanabe
      represents and warrants to, and covenants with, Genelabs as follows:

            4.1   Investment Considerations.

                  (a)   Tanabe is knowledgeable, sophisticated and experienced
      in making, and is qualified to make, decisions with respect to investments
      in shares presenting an investment decision like that involved in the
      purchase of the Purchased Shares, including investments in securities
      issued by companies comparable to Genelabs;

                  (b)   Tanabe acknowledges that it has reviewed the Disclosure
      Materials and has been afforded (i) the opportunity to ask such questions
      as it has deemed necessary of, and to receive answers from,
      representatives of the Genelabs concerning the terms and conditions of the
      offering of the Purchased Shares and the merits and risks of investing in
      such shares; (ii) access to information about Genelabs and the
      Subsidiaries and their financial condition, results of operations,
      business, properties, management and prospects sufficient to enable it to
      evaluate its investment; and (iii) the opportunity to obtain such
      additional information that Genelabs possesses or can acquire without
      unreasonable effort or expense that is necessary to make an informed
      investment decision with respect to the investment;

                  (c)   Tanabe is acquiring the Purchased Shares for its own
      account for investment only and with no present intention of distributing
      any of such shares or any arrangement or understanding with any other
      persons regarding the distribution of such Shares;

                  (d)   Tanabe understands that the Purchased Shares it is
      purchasing are "restricted securities" under the federal securities laws
      inasmuch as they are being acquired from Genelabs in a transaction not
      involving a public offering and that under such laws and applicable
      regulations such securities may be resold without registration under the
      Securities Act only in certain limited circumstances. In this connection
      Tanabe represents that it is familiar with Rule 144, as presently in
      effect, and understands the resale limitations imposed thereby and by the
      Securities Act;

                  (e)   Tanabe qualifies as an "accredited investor" within the
      meaning of Rule 501 of Regulation D promulgated under the Securities Act;
      and

                  (f)   It is understood that the certificates evidencing the
      Purchased Shares shall bear the following legend:

      "These securities have not been registered under the Securities Act of
1933, as amended (the "Act"). They may not be sold, offered for sale, pledged or
hypothecated in the absence of a registration statement in effect with respect
to the securities under such Act or, if requested by Genelabs, an opinion of
counsel reasonably satisfactory to Genelabs and its counsel, that such
registration is not required under such Act."

<PAGE>

            4.2   Due Execution, Delivery and Performance of the
      Agreement. Tanabe is a corporation duly organized, validly existing and in
      good standing under the laws of the jurisdiction of incorporation and has
      the requisite corporate power and authority to enter into and to perform
      the transactions contemplated by this Agreement and otherwise to carry out
      its obligations hereunder. The execution, delivery and performance of this
      Agreement have been duly authorized by all necessary action on the part of
      Tanabe and no further action is required by Tanabe in connection herewith.
      Upon the execution and delivery of this Agreement, this Agreement shall
      constitute a valid and binding obligation of Tanabe enforceable in
      accordance with its terms, except as enforceability may be limited by
      applicable bankruptcy, insolvency, reorganization, moratorium or similar
      laws affecting creditors' and contracting parties' rights generally and
      except as enforceability may be subject to general principles of equity
      (regardless of whether such enforceability is considered in a proceeding
      in equity or at law).

            4.3   Shareholders Meetings.

                  (a)   Quorum. For so long as Tanabe and its affiliates hold
      the Securities they shall vote all of the Purchased Shares in any and all
      meetings of the shareholders of Genelabs.

                  (b)   Voting. For a period of two (2) years from the date
      hereof, Tanabe and its affiliates shall vote all of the Purchased Shares
      for any and all proposals submitted by Genelabs to the vote of its
      shareholders, including but not limited to the election of directors, in
      accordance with the recommendations of the Board of Directors of Genelabs,
      or any committee thereof, to the shareholders with respect to such
      proposals.

            4.4   Purchase of Voting Securities. For a period of two (2) years
      from the date hereof, Tanabe and its affiliates shall not, in the
      aggregate, purchase, acquire or beneficially own, or offer or agree to
      purchase, acquire or beneficially own, directly or indirectly, or alone or
      in concert with others, by purchase, gift, or otherwise, an aggregate of
      nineteen and nine-tenths percent (19.9%) or more of any class of voting
      securities of Genelabs, or any successor to or affiliate of Genelabs by
      merger, consolidation, sale of assets, combination or otherwise.

            4.5   Transfer of Purchased Shares. For a period of two (2) years
      from the date hereof, Tanabe and its affiliates agree that, without the
      prior written consent of Genelabs, they (a) will not, directly or
      indirectly, offer, sell, agree to offer or sell, solicit offers to
      purchase, grant any call option or purchase any put option with respect
      to, pledge, borrow or otherwise dispose of any of the Purchased Shares,
      and (b) will not establish or increase any "put equivalent position" or
      liquidate or decrease any "call equivalent position" with respect to the
      Purchased Shares (in each case within the meaning of Section 16 of the
      Securities Exchange Act of 1934, as amended, and the rules and regulations
      promulgated thereunder), or otherwise enter into any swap, derivative or
      other transaction or arrangement that transfers to another, in whole or in
      part, any economic consequence of ownership of the Purchased Shares,
      whether or not such transaction is to be settled by delivery of the
      Purchased Shares, other securities, cash or other consideration.

<PAGE>

      5.    Registration Rights

            5.1   Certain Definitions. As used in this Section, the following
      terms shall have the following respective meanings:

                  (a)   "Registration Expenses" shall mean all expenses incurred
      in complying with registrations, filings or qualifications under Sections
      5.2 and 5.3 hereof, including, without limitation, all registration,
      qualification and filing fees, accounting fees, printing expenses, escrow
      fees, fees and disbursements of counsel for Genelabs, blue sky fees and
      expenses, the expense of any special audits incident to or required by any
      such registration (but excluding the compensation of regular employees of
      Genelabs and Selling Expenses), and fees and expenses of one special
      counsel, if any, for the Tanabe not to exceed $25,000.

                  (b)   "Selling Expenses" shall mean all underwriting discounts
      and selling commissions applicable to the sale, inclusive of all fees and
      disbursements of counsel for Tanabe (excluding amounts to be paid to one
      special counsel for Tanabe under Registration Expenses).

            5.2   Piggyback Registration.

                  (a)   Triggering Event. The rights described in this Section
      5.2 shall be available to Tanabe on and after the second anniversary of
      the date of this Agreement if and only if (i) Tanabe shall desire to sell
      some or all of the Purchased Shares, (ii) Tanabe shall contact one or more
      reputable brokerage or investment banking firms to assist Tanabe in
      executing such sale, and (iii) Tanabe shall be advised by such firms (and
      provide reasonable evidence of such advice to Genelabs) that the stock
      price, trading commission and trading execution terms available to Tanabe
      in selling the Purchased Shares are not substantially similar to the
      price, commission and terms that would be available to any other person
      seeking to sell a similar number of shares that are registered under the
      Securities Act of 1933.

                  (b)   Registration. Provided that the rights provided
      hereunder are available under the provisions of Section 5.2(a), if at any
      time or from time to time, Genelabs shall determine to register any of its
      securities, either for its own account or the account of a security holder
      or holders exercising their respective demand registration rights, other
      than a Special Registration Statement, which shall mean: (i) a
      registration on Form S-8 (or a similar or successor form) relating solely
      to employee stock option, stock purchase or other benefit plans, or (ii) a
      registration on Form S-4 (or similar or successor form) relating solely to
      a Commission Rule 145 transaction, Genelabs will:

                        (i)   promptly give to Tanabe written notice thereof;
      and

                        (ii)  include in such registration (and any related
      qualification under blue sky laws or other compliance), and in any
      underwriting involved therein, all the Purchased Shares specified in a
      written request or requests, made by Tanabe within twenty (20) days after
      mailing of written notice by Genelabs.

<PAGE>
                  (c)   Underwriting. If the registration of which Genelabs
      gives notice is for a registered public offering involving an
      underwriting, Genelabs shall so advise Tanabe as a part of the written
      notice given pursuant to Section 5.2(b)(i). In such event the right of
      Tanabe to registration pursuant to Section 5.2 shall be conditioned upon
      Tanabe's participation in such underwriting and the inclusion of Tanabe's
      Purchased Shares in the underwriting to the extent provided herein. Tanabe
      shall (together with Genelabs and the other holders distributing their
      securities through such underwriting) enter into an underwriting agreement
      in customary form with the representative of the underwriter
      ("Underwriter's Representative"). Notwithstanding any other provision of
      this Section 5.2, if the Underwriter's Representative determines that
      marketing factors require a limitation of the number of shares to be
      underwritten, the underwriter may limit the number of Purchased Shares to
      be included in the registration and underwriting and such number shall be
      allocated, first, to Genelabs, second to Tanabe and other holders who have
      registration rights electing to participate in such underwriting, on a pro
      rata basis based on the total number of shares held by Tanabe and such
      participating holders, and, third, to any other shareholder of Genelabs on
      a pro rata basis. If Tanabe disapproves of the terms of any such
      underwriting, Tanabe may elect to withdraw therefrom by written notice to
      Genelabs and the Underwriter's Representative. Any securities excluded or
      withdrawn from such underwriting shall be withdrawn from such
      registration.

            5.3   Expenses of Registration. All Registration Expenses incurred
      in connection with any registration, qualification or compliance pursuant
      to Sections 5.2 shall be borne by Genelabs; and, unless otherwise stated,
      all Selling Expenses relating to shares registered by Tanabe shall be
      borne by Tanabe on the basis of the number of shares so registered.

            5.4   Registration Procedures. In the case of each registration,
      qualification or compliance effected by Genelabs pursuant to this Section
      6, Genelabs will keep Tanabe advised in writing as to the initiation of
      each registration, qualification and compliance and as to the completion
      thereof. Genelabs will as expeditiously as reasonably possible:

                  (a)   Prepare and file with the Commission a registration
      statement with respect to such securities and use its best efforts to
      cause such registration statement to become and remain effective for a
      period of one hundred twenty (120) days or until Tanabe has completed the
      distribution described in the registration statement relating thereto,
      whichever occurs first.

                  (b)   Furnish to Tanabe and to each underwriter such number of
      copies of the registration statement and the prospectus included therein
      (including each preliminary prospectus) as such persons may reasonably
      request in order to facilitate the intended disposition of the Purchased
      Shares covered by such registration statement.

                  (c)   Prepare and file with the Commission such amendments and
      supplements to such registration statement and the prospectus used in
      connection with such registration statement as may be necessary to comply
      with the provisions of the Securities Act with respect to the disposition
      of all securities covered by such registration statement for the period
      set forth in paragraph (a) above.

<PAGE>

                  (d)   Use its best efforts to register and qualify the
      securities covered by such registration statement under such other
      securities or blue sky laws of such jurisdictions as shall be reasonably
      requested by Tanabe; provided that Genelabs shall not be required in
      connection therewith or as a condition thereto to qualify to do business
      or to file a general consent to service of process in any such states or
      jurisdictions.

                  (e)   In the event of any underwritten public offering, enter
      into and perform its obligations under an underwriting agreement, in usual
      and customary form, with the Underwriter's Representative of such
      offering. Tanabe shall also enter into and perform its obligations under
      such an agreement.

                  (f)   Notify Tanabe at any time when a prospectus relating
      thereto is required to be delivered under the Securities Act of the
      happening of any event as a result of which the prospectus included in
      such registration statement, as then in effect, includes an untrue
      statement of a material fact or omits to state a material fact required to
      be stated therein or necessary to make the statements therein not
      misleading in the light of the circumstances then existing. Genelabs will
      use reasonable efforts to amend or supplement such prospectus in order to
      cause such prospectus not to include any untrue statement of a material
      fact or omit to state a material fact required to be stated therein or
      necessary to make the statements therein not misleading in light of the
      circumstances then existing.

                  (g)   Use its best efforts to furnish, on the date that such
      Purchased Shares are delivered to the underwriters for sale, if such
      securities are being sold through underwriters, (i) an opinion, dated as
      of such date, of the counsel representing Genelabs for the purposes of
      such registration, in form and substance as is customarily given to
      underwriters in an underwritten public offering, addressed to the
      underwriters, if any, and (ii) a letter dated as of such date, from the
      independent certified public accountants of Genelabs, in form and
      substance as is customarily given by independent certified public
      accountants to underwriters in an underwritten public offering addressed
      to the underwriters.

                  (h)   Cause all such Purchased Shares registered pursuant
      hereto to be listed on each securities exchange on which similar
      securities issued by Genelabs are then listed; or, if not previously
      listed on any exchange, then cause all such Purchased Shares to be listed
      on the New York Stock Exchange, American Stock Exchange or the NASDAQ
      National Market System.

                  (i)   Provide a transfer agent and registrar for all Purchased
      Shares registered pursuant hereunder and a CUSIP number for all such
      Purchased Shares, in each case not later than the effective date of such
      registration.

<PAGE>

            5.5   Indemnification.

                  (a)   To the extent permitted by law, Genelabs will, and does
      hereby undertake to, indemnify and hold harmless Tanabe, each of its
      officers, directors and partners, and each person controlling Tanabe
      within the meaning of Section 15 of the Securities Act, with respect to
      which registration, qualification or compliance has been effected pursuant
      to this Section 5, and each underwriter, if any, and each person who
      controls any underwriter within the meaning of Section 15 of the
      Securities Act, against all expenses, claims, losses, damages and
      liabilities (or actions in respect thereof), including settlement of any
      litigation, commenced or threatened, to which they may become subject
      under the Securities Act, the Exchange Act, or other federal or state law,
      arising out of or based on compliance with, any untrue statement (or
      alleged untrue statement) of a material fact contained in any registration
      statement, prospectus (preliminary or final), offering circular or other
      document or amendments thereto, or arising out of or based on any omission
      (or alleged omission) to state therein a material fact required to be
      stated therein or necessary to make the statements therein, in light of
      the circumstances in which they were made, not misleading, or arising out
      of or any violation by Genelabs of any federal, state or common law rule
      or regulation applicable to Genelabs and relating to action or inaction
      required of Genelabs in connection with any such registration,
      qualification or compliance, and will reimburse Tanabe, each of its
      officers, directors and partners, and each person controlling Tanabe, each
      such underwriter and each person who controls any such underwriter, for
      any legal and any other expenses reasonably incurred in connection with
      investigating, preparing or defending any such claim, loss, damage,
      liability or action, provided that Genelabs will not be liable in any such
      case to the extent that any such claim, loss, damage, liability or expense
      arises out of or is based on any untrue statement or omission or alleged
      untrue statement or omission, made in reliance upon and in conformity with
      written information furnished to Genelabs by an instrument executed by
      Tanabe or underwriter expressly for use in connection with such
      registration.

                  (b)   To the extent permitted by law, Tanabe will, if
      Purchased Shares held by Tanabe are included in the securities as to which
      such registration, qualification or compliance is being effected,
      indemnify and hold harmless Genelabs, each of its directors and officers,
      agents and employees, each underwriter, if any, of Genelabs' securities
      covered by such a registration statement, each person who controls
      Genelabs or such underwriter within the meaning of Section 15 of the
      Securities Act, and Tanabe, each of its officers, directors and partners
      and each person controlling Tanabe within the meaning of Section 15 of the
      Securities Act, against all claims, losses, damages and liabilities (or
      actions in respect thereof to which they may become subject) arising out
      of or based on any of the following: (i) any untrue statement or alleged
      untrue statement of a material fact contained in such registration
      statement or incorporated reference therein, including any preliminary
      prospectus or final prospectus contained therein or any amendments or
      supplements thereto, (ii) the omission or alleged omission to state
      therein a material fact required to be stated therein, or necessary to
      make the statements therein not misleading, or (iii) any violation or
      alleged violation by Genelabs of the Securities

<PAGE>

      Act (collectively, a "Holder Violation"), in each case to the extent (and
      only to the extent) that such Holder Violation occurs in reliance upon and
      in conformity with written information furnished by Tanabe under an
      instrument duly executed by Tanabe and stated to be specifically for use
      in connection with such registration; and Tanabe will reimburse any legal
      or other expenses reasonably incurred by Genelabs or any such director,
      officer, controlling person, or underwriter in connection with
      investigating or defending any such loss, claim, damage, liability or
      action if it is judicially determined that there was such a Holder
      Violation; provided, however, that the indemnity agreement contained in
      this Section 5.5(b) shall not apply to amounts paid in settlement of any
      such loss, claim, damage, liability or action if such settlement is
      effected without the consent of Tanabe, which consent shall not be
      unreasonably withheld; provided further, that in no event shall any
      indemnity under this Section 5.5 exceed the net proceeds from the offering
      received by Tanabe.

                  (c)   Each party entitled to indemnification under this
      Section 5.5 (the "Indemnified Party") shall give notice to the party
      required to provide indemnification (the "Indemnifying Party") promptly
      after such Indemnified Party has actual knowledge of any claim as to which
      indemnity may be sought, and shall deliver written notice to the
      Indemnifying Party of commencement thereof. The Indemnifying Party, at its
      sole option, may participate in or assume the defense of any such claim or
      any litigation resulting therefrom with counsel reasonably satisfactory to
      the Indemnified Party, and the Indemnified Party may participate in such
      defense at Indemnified Party's expense. The failure of any Indemnified
      Party to give notice as provided herein shall not relieve the Indemnifying
      Party of its obligations under this Section 6 except to the extent that
      such failure to give notice shall materially adversely affect the
      Indemnifying Party in the defense of any such litigation. No Indemnifying
      Party, in the defense of any such claim or litigation shall, except with
      the consent of each Indemnified Party, consent to entry of any judgment or
      enter into any settlement which does not include as an unconditional term
      a release from all liability in respect to such claim or litigation by the
      claimant or plaintiff to such Indemnified Party.

                  (d)   If the indemnification provided for in this Section 5.5
      is held by a court of competent jurisdiction to be unavailable to an
      indemnified party with respect to any losses, claims, damages or
      liabilities referred to herein, the indemnifying party, in lieu of
      indemnifying such indemnified party thereunder, shall to the extent
      permitted by applicable law contribute to the amount paid or payable by
      such indemnified party as a result of such loss, claim, damage or
      liability in such proportion as is appropriate to reflect the relative
      fault of the indemnifying party on the one hand and of the indemnified
      party on the other in connection with the violation(s) that resulted in
      such loss, claim, damage or liability, as well as any other relevant
      equitable considerations. The relative fault of the indemnifying party and
      of the indemnified party shall be determined by a court of law by
      reference to, among other things, whether the untrue or alleged untrue
      statement of a material fact or the omission to state a material fact
      relates to information supplied by the indemnifying party or by the
      indemnified party and the parties' relative intent, knowledge, access to
      information and opportunity to correct or prevent such

<PAGE>

      statement or omission; provided, that in no event shall any contribution
      by Tanabe hereunder exceed the net proceeds from the offering received by
      Tanabe.

                  (e)   The obligations of Genelabs and Tanabe under this
      Section 5.5 shall survive completion of any offering of Purchased Shares
      in a registration statement and the termination of this Agreement. No
      Indemnifying Party, in the defense of any such claim or litigation, shall,
      except with the consent of each Indemnified Party, consent to entry of any
      judgment or enter into any settlement which does not include as an
      unconditional term thereof the giving by the claimant or plaintiff to such
      Indemnified Party of a release from all liability in respect to such claim
      or litigation.

            5.6   Information From Tanabe. Tanabe shall furnish to Genelabs such
      information regarding Tanabe and the distribution proposed by Tanabe as
      Genelabs may reasonably request in writing and as shall be required in
      connection with any registration, qualification or compliance referred to
      in this Section 5.

            5.7   Rule 144 Reporting. With a view to making available the
      benefits of certain rules and regulations of the Commission which may at
      any time permit the sale of the Purchased Shares to the public without
      registration, Genelabs agrees to:

                  (a)   Make and keep public information available, as those
      terms are understood and defined in Rule 144 under the Securities Act at
      all times;

                  (b)   File with the Commission in a timely manner all reports
      and other documents required of Genelabs under the Securities Act and the
      Exchange Act; and

                  (c)   Furnish Tanabe forthwith upon request a written
      statement as to its compliance with the reporting requirements of Rule
      144, and of its compliance with the Securities Act and the Exchange Act;
      Genelabs shall provide forthwith upon written request a copy of the most
      recent annual or quarterly report of Genelabs, and such other reports and
      documents of Genelabs as Tanabe may reasonably request in availing itself
      of any rule or regulation of the Commission allowing Tanabe to sell any
      such Purchased Shares without registration.

            5.8   Assignment of Registration Rights. The rights to cause
      Genelabs to register the Purchased Shares and related rights granted
      Tanabe under Section 5 may be assigned to any transferee upon a transfer
      of any Purchased Shares; provided, that Genelabs receives notice of such
      assignment, and the transferee agrees to be bound by the registration
      rights provisions in Section 5 of this Agreement.

      6.    Survival of Representations, Warranties and Agreements.
      Notwithstanding any investigation made by any party to this Agreement, all
      covenants, agreements, representations and warranties made by Genelabs and
      Tanabe herein shall survive the execution of this Agreement, the delivery
      to Tanabe of the Purchased Shares being purchased and the payment
      therefor, except to the extent otherwise provided herein.

<PAGE>
      7.       Miscellaneous.

               7.1   Notices. Any consent, notice or report required or
      permitted to be given or made under this Agreement by one of the parties
      hereto to the other shall be in writing, delivered personally or by
      facsimile (and promptly confirmed by telephone, personal delivery or
      courier) or courier, postage prepaid (where applicable), addressed to such
      other party at its address indicated below, or to such other address as
      the addressee shall have last furnished in writing to the addressor and
      shall be effective upon receipt by the addressee.

IF TO GENELABS:                     Genelabs Technologies, Inc.
                                    505 Penobscot Drive
                                    Redwood City, CA 94063
                                    Attn: General Counsel
                                    Facsimile: (650) 368-0709

IF TO TANABE:                       Tanabe Seiyaku Co., Ltd
                                    2-10 Dosho-machi 3-chome
                                    Chuo-ku, Osaka, Japan
                                    Attn: General Manager of Legal Division
                                    Facsimile: +81 6 6202 5040

               7.2   Entire Agreement. This Agreement contains the entire
      understanding of the parties with respect to the subject matter hereof.
      All express or implied agreements and understandings, either oral or
      written, heretofore made are expressly merged in and made a part of this
      Agreement.

               7.3   Amendments and Waivers. This Agreement may not be modified
      or amended except pursuant to an instrument in writing signed by Genelabs
      and Tanabe. The waiver by either party hereto of any right hereunder or
      the failure to perform or of a breach by the other party shall not be
      deemed a waiver of any other right hereunder or of any other breach or
      failure by said other party whether of a similar nature or otherwise.

               7.4   Headings. The headings of the various sections of this
      Agreement have been inserted for convenience of reference only and shall
      not be deemed to be part of this Agreement.

               7.5   Severability. In case any provision contained in this
      Agreement should be invalid, illegal or unenforceable in any respect, the
      validity, legality and enforceability of the remaining provisions
      contained herein shall not in any way be affected or impaired thereby.

               7.6   Governing Law. This Agreement shall be governed by and
      construed in accordance with the laws of the State of California (without
      giving effect to the choice of law provisions thereof) and the federal law
      of the United States of America.

<PAGE>

               7.7   Counterparts. This Agreement may be executed in two or more
      counterparts, each of which shall constitute an original, but all of
      which, when taken together, shall constitute but one instrument, and shall
      become effective when one or more counterparts have been signed by each
      party hereto and delivered to the other parties.

               7.8   Expenses. Except as otherwise specifically provided herein,
      each party shall bear its own expenses in connection with this Agreement.

               7.9   Publicity. Neither party hereto shall issue any press
      releases or otherwise make any public statement with respect to the
      transactions contemplated by this Agreement without the prior written
      consent of the other party, except as may be required by applicable law or
      regulation.

<PAGE>

      IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be
      executed by their duly authorized representatives as of the day and year
      first above written.

GENELABS TECHNOLOGIES, INC.

By: ___________________________________________
Name: Irene A. Chow, Ph.D.
Its:  Chairman and Chief Executive Officer

TANABE SEIYAKU CO., LTD.

By: ___________________________________________
Name:
Its:

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00065-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00065-of-00352.parquet"}]]