Document:

SECOND AMENDMENT TO
                            REVOLVING NOTE AGREEMENT

      This First Amendment to the Revolving Note Agreement ("the  AMENDMENT") is
entered into as of June 20,  2006,  by and among Marine  Growth  Ventures  Inc.,
Marine Growth Charter, Inc., Marine Growth Finance, Inc., Marine Growth Freight,
Inc., Marine Growth Real Estate,  Inc., and Gulf Casino Cruises,  Inc., Delaware
corporations   (collectively  the  "Borrower"),   and  Frank  P.  Crivello  (the
"Lender").

      WHEREAS,  the  Borrower  and the Lender are  parties to a  Revolving  Note
Agreement dated as of January 5, 2006 (the "NOTE AGREEMENT")  pursuant to which,
among other things, the Borrower promised to pay the Lender the principal sum of
up to Fifty Thousand Dollars ($50,000.00), or so much thereof as shall have been
advanced by the Lender to the Borrower plus  interest  thereon at an annual rate
equal to ten  percent  (10%) on the  Maturity  date of such Note  being June 30,
2006.

      WHEREAS, the Note Agreement was amended on March 31, 2006,  permitting the
Borrower to acquire an additional Fifty Thousand  Dollars  ($50,000.00) in funds
from the Lender.

      WHEREAS,  the  parties  desire  to make a certain  amendment  to the First
Amendment to the Revolving  Note  Agreement to permit the Borrower to acquire an
additional Fifty Thousand Dollars ($50,000.00) in funds from the Lender.

      NOW, THEREFORE,  in consideration of the premises and the mutual covenants
contained in this Amendment the parties agree as follows:

      1.  Paragraph One of the Note  Agreement is hereby amended and restated to
provide as follows:

            FOR VALUE  RECEIVED,  Marine  Growth  Ventures  Inc.,  Marine Growth
      Charter,  Inc., Marine Growth Finance,  Inc., Marine Growth Freight, Inc.,
      Marine Growth Real Estate,  Inc., and Gulf Casino Cruises,  Inc., Delaware
      corporations (collectively the "Borrower"), having an office at 3408 Dover
      Road, Pompano Beach, Florida 33062, hereby promises to pay to the order of
      Frank P. Crivello (the  "Lender"),  at the Lender's office located at 3408
      Dover Road,  Pompano  Beach,  Florida  33062 or at such other place in the
      continental  United  States as the Lender may  designate in writing,  upon
      demand, in lawful money of the United States, and in immediately available
      funds,  the  principal  sum of up to ONE HUNDRED  FIFTY  THOUSAND  DOLLARS
      ($150,000),  or so much thereof as shall have been  advanced by the Lender
      to the Borrower as hereinafter set forth and then be  outstanding,  and to
      pay interest  thereon on the Maturity  Date at an annual rate equal to ten
      percent (10%).

<PAGE>

      2. This Amendment constitutes the sole and entire agreement of the parties
with respect to the subject matter hereof.  Except as amended hereby,  all other
terms and  conditions  of the Note  Agreement  shall  remain  in full  force and
effect.

      IN WITNESS WHEREOF, the undersigned have executed this Amendment as of the
date first above written.

LENDER

/s/ Frank P. Crivello
Frank P. Crivello

BORROWER

/s/ Paul L. Schwabe                       /s/ Paul L. Schwabe
---------------------------               ------------------------
Paul L. Schwabe, Secretary                Paul L. Schwabe, Secretary
Marine Growth Ventures, Inc.              Marine Growth Charter, Inc.

/s/ Paul L. Schwabe                       /s/ Paul L. Schwabe
---------------------------               -------------------------
Paul L. Schwabe, Secretary                Paul L. Schwabe, Secretary
Marine Growth Finance, Inc.               Marine Growth Freight, Inc.

/s/ Paul L. Schwabe                       /s/ Paul L. Schwabe
---------------------------               ------------------------
Paul L. Schwabe, Secretary                Paul L. Schwabe, Secretary
Marine Growth Real Estate, Inc.           Gulf Casino Cruises, Inc.Cooperation Joint Venture Agreement for Formation of a New Entity

Chapter 1 Generals
According to the laws and  regulations of People's  Republic of China (herein"
PRC"),  and with the equality and mutual benefit,  Guangzhou  Konzern Medicine
Co.  Ltd.   (herein   "Konzern"),   Guangzhou   Ji'nan  Science  &  Technology
Industrial  Group Co., Ltd.  (herein  "JSIG" the agent of Ji'nan  University),
and the  technology  inventor Mr.  Dongshen  Yao,  agree to set up a high tech
stock holding corporation in Guangzhou after friendly negotiation.

Chapter 2 Capital Contribution Parties
1. The contribution parties to the Agreement are as below:
Party  A:  Guangzhou  Konzern  Medicine  Co.  Ltd.  Address:   Rm702,  Guangri
Mansion, No.9 Siyou Nan Rd, Wuyang New City, Guangzhou, Post code: 510600.

Party B:  Guangzhou  Ji'nan Science & Technology  Industrial  Group Co., Ltd.,
the agent of Ji'nan University.
Address: No.105 Zhongshan Avenue, Guangzhou

Party C: Mr. Dongsheng Yao, the new technology inventor.
Address:   Ji'nan   University,   No.601  Huangpu  Avenue,   Tianhe  District,
Guangzhou.

Chapter 3 Enterprise Nature
2. According to the laws and regulations of People's Republic of China (herein
"PRC"), the three shareholders above fully agree to set up a corporation named
________________ (herein "New Co"), and do the business as described below.

3. All the business activities we take part in should be permitted by the laws,
regulations and permissions of People's Republic of China or local government.
The corporation address is: Guangri Mansion, 7 FL, 9 Siyou Nan Rd, Wuyang New
City, Guangzhou.

4. This corporation is a limited liability company. The responsibility of each
shareholder is limited to its capital contribution. Each shareholder shall share
the income and take the risk according to the percentage of their capital
contribution in the New Co's registered capital.

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Chapter 4 Mission and Business Scope
5. The mission of this corporation is to strengthen the economy and technology
cooperation, exchange business management experience, serve the society, improve
the economic profitability, and obtain the satisfied income for all
shareholders.

6. The business scope includes (subject to the business license to be issued):
test equipment. bio products, enzyme products, the research, production and sale
of medical equipments, and technology transfer.

Chapter 5 Total Investment and the Registered Capital
7. The total investment of this corporation is RMB25million. Konzern will invest
RMB17.5million. The first installment of the registered capital shall be
RMB5million. JSIG and Mr. Dongsheng Yao will contribute four patents of
Aflatoxin-detoxifizyme evaluated at RMB7.5million which is treated as their
investment.

8.Konzern will have 70% ownership of the RMB5million registered capital of the
New Co. JSIG and Mr. Dongsheng Yao will each have 15% ownership of the New Co..
The payment of RMB5million of the registered capital will be remit by Konzern to
________________ [Account No. of the New Co] within 15 days after the Agreement
is signed. The rest RMB12.50million investment of Konzern will be paid in 2
years according to the progress of the project.

9. The equity structure will be adjusted with the increase of the registered
capital. But before the New Co get public, the total equity in the New Co held
by Party B and Party C shall be no less than 15%, among which Party B will hold
no less than 5%and Party C will hold no less than 10%.

10. The shareholder must get approval from other shareholders if it transfers
its partial or all shares to outside parties. Other shareholders have the right
of first refusal to purchase these shares. If other shareholders deem the
transfer price is too high, the selling shareholder need to have the asset
evaluation authority to evaluate its shares, and the transfer price will be
based on the evaluating result. If other shareholders still deem the price is
high and do not want to buy, the selling shareholder can transfer its shares to
outside parties.

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Chapter 6 Rights and Obligations of Shareholders.
11. The shareholders have the following rights:
(1) Voting rights and the rights to be voted;
(2) Dividend distribution according to the percentage of the investment;
(3) supervising, inquiring or censoring the daily management and business
activities of the corporation;
(4) Voting rights in the shareholders meetings on the important decision about
the company;
(5) Sharing the residual property in accordance to his investment proportion
after the corporation closes the business.

12. Obligations of the shareholders:
(1) Paying investment according to the contract;
(2) Taking the responsibilities in accordance to his investment proportion;
(3) The investment can not be drew back once the capital was invested.;
(4) Carrying out the corporation's regulations and stipulations, keeping the
business secret and technique confidential;
(5) Providing reasonable advice for better management;
(6) Within one month from the formation of the New Co, it shall pay Party B and
Party C technology fee at the aggregate of RMB1million.
(7) After the establishment of the New Co., Party B and Party C should transfer
the 4 aflatoxin patents, originally held by the Ji'nan Univerisity, to the New
Co, to be owned by the New Co., within 2 months after the New Co. pay Party B
and Party C the initial technique service fee of RMB 1 million. Without the
consensus of all shareholders, no one can transfer the intellectual property or
entrust the implementation or any other actions to implement the intellectual
property. The above mentioned contributed initial technology achievements and
the further achievement derived from development such technology are owned by
the New Co. The honors of the achievements (with the exception of thesis and
articles) are shared by the Party A, Party B and Party C. The rights of
authorship of the thesis and articles mainly belong to Party B and Party C.

13 Each Party shall not release the technology materials to any other third
party. Otherwise, the breaching party shall bear the breach liability.

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<PAGE>

Chapter 7 Organization
14 The New Co. has its R&D center which locates in the Ji'nan University and is
responsible for relevant technology achievement development and technology study
with the support of Ji'nan University. (The purchased equipments according to
the research development are located in the R&D centre for usage but are owned
by the New Co.) The R&D center is also responsible for application for relevant
technology projects to the government and for striving to obtain the support
from the government. The other departments of the New Co. are responsible for
the market operation of the New Co. and assist to obtain the support and
relevant preferential policies, which are to be owned by the New Co., from the
government.

15 The New Co. has shareholder meeting. The shah older meeting is the highest
decision making authority which will make all the important decisions for the
company. The following activities must be approved by all shareholders,
including the change of share holders, change of the share proportion,
investments or guaranty to others, the merger, separation or the dissolution of
the company, the change of the company's articles of association, and the change
of the business model. All the other activities could be approved by majority
shareholders.

16 The New Co.  has  board.  The  board  is  responsible  to the  shareholding
meeting.  The  official  establishment  date of the board is the date that the
New Co. obtain the registration.

17 The board has five directors. Three directors will be designated by Party A.
Party B and Party C will designate one director each. The board will have one
chairman and two vice chairmen. The chairman will be designated by Party A, and
vice chairman will be designated by Party B and Party C. The term of board
member is three years and can be renewed through designation.

18 The chairman of the board is the legal representative of the New Co. The
chairman can appoint the vice chairman or other directors to implement the
powers of if the chairman cannot implement its power for some reasons.

19 The board meeting will be held at least once each year. The meeting is called
and hosted by the chairman. The chairman can call the temporary meeting if more
than one third of the directors propose. The meeting records shall be filed and
saved. Only when two thirds of the directors or more attend the meeting, such
meeting can be held. If the director cannot attend the meeting, it will be
deemed valid if he can submit the writing opinion within 15 days after receiving
the notice. If the director neither attend the meeting nor submit the writing
opinion and reasonable reasons within 1 month after receiving the notice so that
the board decisions cannot passed by due number of directors, the shareholders
representing more than 10% voting power can call and host the meeting and pass
valid resolutions.

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<PAGE>

20 The New Co. has supervisory commission, which is composed by three members.
Party B and Party will designate one each. Party C will recommend a
representative from the employees.

21 The New Co. has 1 general manager, employed by the board, who will be
responsible for the daily operation and submitting the proposal on the
management structure and management personnel to the board for the approval.

22 Party C, the inventor of the patents, will be fully responsible for the
research and development of the company, and can be appointed as vice general
manager and Chief Technology Officer upon his consent.

Chapter 8 Taxes, Accounting, Audit
23 The New Co. will pay taxes  according to the related  laws and  regulations
of China.

24 The New  Co.  will  set up  accounting  department  and  employ  accounting
personnel  according  to the  related  accounting  regulations  of  the  joint
venture.  The accountant and cashier will be designated by Party A and Party B
one each. The  accounting  bylaws of the New Co. will be reported to the local
finance department.

Chapter 9 Cooperation Term
25. The term of the New Co. is twenty years. The incorporation date is the date
of the issuance of the business license of the New Co.
    Proposed by one Party and approved by all directors, the New Co. can apply
for extension of the term to the local government six months prior to the
termination.

Chapter 10 Asset Disposal after the Term Expiration
26 When the term is expired or the term is terminated in advance, the New Co.
will conduct liquidation according to the related laws and regulations. The
liquidated assets will be allocated among investors according to the share
proportion.

                                       5
<PAGE>

Chapter 11 Insurance
27 The New Co.'s various property insurance shall choose the People's Insurance
Company of China as insurer. The insurance type, valuation and term shall be
determined by the board of directors in accordance with the stipulations of the
People's Insurance Company of China.

Chapter 12 The Amendment, Alteration and Termination of the Contract 28 The
amendment of this Agreement or its appendices shall come into force only after
the Parties sign the written agreement and the local government approves such
amendment.

29 In case the Agreement cannot be enforce due to Force Majeure or the company
has losses in successive years and is unable to continue to operation, with the
consents of the Parties, the New Co. can submit for approval from the local
government to terminate the joint venture agreement in advance.

Chapter 13 Liabilities for Breach of Contract
30 None of the Party A, Party B nor Party C should transfer, lease, or authorize
in any other form to a third party. Otherwise, the breaching party shall pay the
non-breaching party 20% of registered capital of the New Co. as the liquidated
damages and compensate all arising economic losses to the non-breaching party.

31 After the establishment of the New Co., all of the research products,
patents, non-patent technologies developed by the New Co. are owned by the New
Co. Neither Party can unilaterally transfer, lease and authorize such
intellectual property to any third party. Otherwise, the breaching party shall
undertake all arising losses.

32 This project is a confidential project of the Ministry of Science and
Technology of China. None of Parties can disclose any of information of the
project to the third party. The breaching Party should bear all breach
responsibilities and criminal liabilities, if any.

33 If Party A fails to contribute the capital according to Article 7 of this
Agreement, which impairs the development of the project, the share proportion of
Party A will be reduced accordingly to its actual investment in the New Co.. The
reduced portion of equity interest will be assigned to the Party B and Party C
or the Party B and Party C will have the right to look for new investor.

                                       6
<PAGE>

Chapter 14 Force Majeure
34 Should the enforcement of the Agreement is influenced or the Agreement cannot
be enforced as agreed, due to Force Majerue such as earthquake, typhoon, flood,
war and other unforeseen events, the happening and consequences of which are
unpreventable and unavoidable, the prevented party shall immediately notify the
board by telegram, and within 15 days thereafter provide the detailed
information of the events and a valid document for evidence issued by the
relevant public notary organization for explaining the reason of its inability
to execute or delay of the execution of all or part of the Agreement. All
parties shall negotiate to decide whether to terminate the Agreement, to exempt
the part of obligations for implementation of the Agreement, or to delay the
implementation of the Agreement according to the effects of the events on the
enforcement of the Agreement.

Chapter 15 Applicable Law
35 The formation of this Agreement, its validity, interpretation, execution and
settlement of disputes shall be governed by the laws of the People's Republic of
China.

Chapter 16 Result of Dispute
36 Any dispute arising from or in connection with this Contract shall be
resolved through friendly negotiation by the Parties. If the disputes cannot be
solved by negotiation, the dispute will be submitted to the local court where
Party B resides. The Party who fail will bear all the litigation costs. The
Parties can also submit the disputes to the Guangdong Arbitration Commission.

37 In the process of arbitration, the enforcement of the Agreement shall be
continued except those disputable parts under litigation.

Chapter 17 Effectiveness of the Contract and Others
38 The appendices executed in accordance with various principles of this
Agreement are integral parts of this Agreement.

39 The Agreement and its appendices shall come into force from the date of
approval by the local authority, if required, or upon signature if no approval
is required. .

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<PAGE>

40 Should notices in connection with any party's rights and obligations be sent
by Party A, Party B and Party C by telegram, telex and etc., the written notices
shall be sent afterwards. The legal addresses of Party A, Party B and Party C
listed in this Agreement are the mail addresses.

41 The Agreement is the basic legal guideline for each party to establish the
New Co. Should there be any conflicts with other relevant documents, the
Agreement will prevail.

42 The Agreement is signed by the authorized representative of each Party on ,
2006. The will be four originals of the Agreement. Each Party has one and the
New Co. will have one too, which has the same legal validity.

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<PAGE>

Party A:  Guangzhou Konzern Medicine Co. Ltd.
(Signature by legal representative and sealed by company)

Signed and Sealed

Date: July 7, 2006

Party B: Guangzhou Ji'nan Science & Technology Industrial Group Co., Ltd.
(Signature by legal representative and sealed by company)

Signed and Sealed

Date: July 7, 2006

Party C: Mr. Dongsheng Yao (the technology inventor)

Signed and Fingerprinted

Date: July 7, 2006

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