Document:

Exhibit 10.3

 

Chardan
Capital Markets, LLC

17 State Street, Suite 1600

New York, New York 10004

 

February ___,
2019

 

CONFIDENTIAL

 

Dr. Anil R. Diwan

Preseident

Nanoviricides, Inc.

1 Controls Drive

Shelton, CT 06484

 

Dear Dr. Diwan:

 

This letter (the “Agreement”)
constitutes the agreement between Chardan Capital Markets, LLC (“Chardan”) (the “Placement Agent”)
and Nanoviricides, Inc. (the “Company”), that Placement Agent shall serve as the exclusive placement agent for
the Company, on a “reasonable best efforts” basis, in connection with the proposed placement (the “Placement”)
of registered securities (the “Securities”) of the Company, including shares (the “Shares”)
of the Company’s common stock, par value $.001 per share (the “Common Stock”) and warrants to purchase
shares of Common Stock (the “Warrants”). The terms of such Placement and the Securities shall be mutually agreed upon
by the Company and the purchasers (each, a “Purchaser” and collectively, the “Purchasers”)
and nothing herein constitutes that Placement Agent would have the power or authority to bind the Company or any Purchaser or an
obligation for the Company to issue any Securities or complete the Placement. This Agreement and the documents executed and delivered
by the Company and the Purchasers in connection with the Placement shall be collectively referred to herein as the “Transaction
Documents.” The date of the closing of the Placement shall be referred to herein as the “Closing Date.”
The Company expressly acknowledges and agrees that Placement Agent’s obligations hereunder are on a reasonable best efforts
basis only and that the execution of this Agreement does not constitute a commitment by the Placement Agent to purchase the Securities
and does not ensure the successful placement of the Securities or any portion thereof or the success of the Placement Agent with
respect to securing any other financing on behalf of the Company.

 

SECTION 1.         COMPENSATION AND
OTHER FEES.

 

As compensation for
the services provided by the Placement Agent hereunder, the Company agrees to pay to the Placement Agent:

 

The fees set forth
below with respect to the Placement:

 

1.       A
cash fee payable immediately upon the closing of the Placement and equal to 9.0% of the aggregate gross proceeds raised in the
Placement. All fees shall be paid at closing and shall be split equally between Chardan and [ ].

 

2.       $25,000.00
payable to Ellenoff, Grossman and Schole at closing for legal services.

  

     

     

    

 

SECTION 2.         REGISTRATION STATEMENT.

 

The Company represents
and warrants to, and agrees with, the Placement Agent that:

 

(A)         The
Company has filed with the Securities and Exchange Commission (the “Commission”) a registration statement on
Form S-3 (Registration File No. 333-216345) under the Securities Act of 1933, as amended (the “Securities Act”),
which became effective on April 25, 2017, for the registration under the Securities Act of the Shares. At the time of such filing,
the Company met the requirements of Form S-3 under the Securities Act. The Company will file with the Commission pursuant to Rule
424(b) under the Securities Act, and the rules and regulations (the “Rules and Regulations”) of the Commission
promulgated thereunder, a supplement to the form of prospectus included in such registration statement relating to the placement
of the Shares and the plan of distribution thereof and has advised the Placement Agent of all further information (financial and
other) with respect to the Company required to be set forth therein. Each such registration statement, including the exhibits thereto,
as amended at the date of this Agreement, is hereinafter called the “Registration Statement”; such prospectus
in the form in which it appears in the Registration Statement is hereinafter called the “Base Prospectus”; and
the supplemented form of prospectus, in the form in which it will be filed with the Commission pursuant to Rule 424(b) (including
the Base Prospectus as so supplemented) is hereinafter called the “Prospectus Supplement.” Any reference in
this Agreement to the Registration Statement, the Base Prospectus or the Prospectus Supplement shall be deemed to refer to and
include the documents incorporated by reference therein (the “Incorporated Documents”) pursuant to Item 12 of
Form S-3 which were filed under the Securities Exchange Act of 1934, as amended (the “Exchange Act”), on or
before the date of this Agreement, or the issue date of the Base Prospectus or the Prospectus Supplement, as the case may be; and
any reference in this Agreement to the terms “amend,” “amendment” or “supplement” with respect
to the Registration Statement, the Base Prospectus or the Prospectus Supplement shall be deemed to refer to and include the filing
of any document under the Exchange Act after the date of this Agreement, or the issue date of the Base Prospectus or the Prospectus
Supplement, as the case may be, deemed to be incorporated therein by reference. All references in this Agreement to financial statements
and schedules and other information that is “contained,” “included,” “described,” “referenced,”
“set forth” or “stated” in the Registration Statement, the Base Prospectus or the Prospectus Supplement
(and all other references of like import) shall be deemed to mean and include all such financial statements and schedules and other
information that is or is deemed to be incorporated by reference in the Registration Statement, the Base Prospectus or the Prospectus
Supplement, as the case may be. No stop order suspending the effectiveness of the Registration Statement or the use of the Base
Prospectus or the Prospectus Supplement has been issued, and no proceeding for any such purpose is pending or has been initiated
or, to the Company's knowledge, is threatened by the Commission. For purposes of this Agreement, “free writing prospectus”
has the meaning set forth in Rule 405 under the Securities Act and the “Time of Sale Prospectus” means the preliminary
prospectus, if any, together with the free writing prospectuses, if any, used in connection with the Placement, including any documents
incorporated by reference therein.

 

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(B)         The
Registration Statement (and any further documents to be filed with the Commission) contains all exhibits and schedules as required
by the Securities Act. Each of the Registration Statement and any post-effective amendment thereto, at the time it became effective,
complied in all material respects with the Securities Act and the Exchange Act and the applicable Rules and Regulations and did
not and, as amended or supplemented, if applicable, will not, contain any untrue statement of a material fact or omit to state
a material fact required to be stated therein or necessary to make the statements therein not misleading. The Base Prospectus,
the Time of Sale Prospectus, if any, and the Prospectus Supplement, each as of its respective date, comply in all material respects
with the Securities Act and the Exchange Act and the applicable Rules and Regulations. Each of the Base Prospectus, the Time of
Sale Prospectus, if any, and the Prospectus Supplement, as amended or supplemented, did not and will not contain as of the date
thereof any untrue statement of a material fact or omit to state a material fact necessary in order to make the statements therein,
in light of the circumstances under which they were made, not misleading. The Incorporated Documents, when they were filed with
the Commission, conformed in all material respects to the requirements of the Exchange Act and the applicable Rules and Regulations,
and none of such documents, when they were filed with the Commission, contained any untrue statement of a material fact or omitted
to state a material fact necessary to make the statements therein (with respect to Incorporated Documents incorporated by reference
in the Base Prospectus or Prospectus Supplement), in light of the circumstances under which they were made not misleading; and
any further documents so filed and incorporated by reference in the Base Prospectus, the Time of Sale Prospectus, if any, or Prospectus
Supplement, when such documents are filed with the Commission, will conform in all material respects to the requirements of the
Exchange Act and the applicable Rules and Regulations, as applicable, and will not contain any untrue statement of a material fact
or omit to state a material fact necessary to make the statements therein, in light of the circumstances under which they were
made, not misleading. No post-effective amendment to the Registration Statement reflecting any facts or events arising after the
date thereof which represent, individually or in the aggregate, a fundamental change in the information set forth therein is required
to be filed with the Commission. There are no documents required to be filed with the Commission in connection with the transaction
contemplated hereby that (x) have not been filed as required pursuant to the Securities Act or (y) will not be filed within the
requisite time period. There are no contracts or other documents required to be described in the Base Prospectus, the Time of Sale
Prospectus, if any, or Prospectus Supplement, or to be filed as exhibits or schedules to the Registration Statement, that have
not been described or filed as required.

 

(C)          The
Company is eligible to use free writing prospectuses in connection with the Placement pursuant to Rules 164 and 433 under the Securities
Act. Any free writing prospectus that the Company is required to file pursuant to Rule 433(d) under the Securities Act has been,
or will be, filed with the Commission in accordance with the requirements of the Securities Act and the applicable rules and regulations
of the Commission thereunder. Each free writing prospectus that the Company has filed, or is required to file, pursuant to Rule
433(d) under the Securities Act or that was prepared by or behalf of or used by the Company complies or will comply in all material
respects with the requirements of the Securities Act and the applicable rules and regulations of the Commission thereunder. The
Company will not, without the prior consent of the Placement Agent, prepare, use or refer to, any free writing prospectus.

 

(D)         The
Company has delivered, or will as promptly as practicable deliver, to the Placement Agent complete conformed copies of the Registration
Statement and of each consent and certificate of experts, as applicable, filed as a part thereof, and conformed copies of the Registration
Statement (without exhibits), the Base Prospectus, the Time of Sale Prospectus, if any, and the Prospectus Supplement, as amended
or supplemented, in such quantities and at such places as the Placement Agent reasonably requests. Neither the Company nor any
of its directors and officers has distributed and none of them will distribute, prior to the Closing Date, any offering material
in connection with the offering and sale of the Shares other than the Base Prospectus, the Time of Sale Prospectus, if any, the
Prospectus Supplement, the Registration Statement, copies of the documents incorporated by reference therein and any other materials
permitted by the Securities Act.

 

SECTION 3.        REPRESENTATIONS
AND WARRANTIES. Except as set forth under the corresponding section of the Disclosure Schedules which Disclosure Schedules
shall be deemed a part hereof, the Company hereby makes the representations and warranties set forth below to the Placement Agent.

 

(a)       Subsidiaries.
The Company has no direct or indirect subsidiaries. Therefore, all other references to the Subsidiaries or any of them in the Transaction
Documents shall be disregarded.

 

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(b)
       Organization and Qualification. The Company and each of the Subsidiaries is an
entity duly incorporated or otherwise organized, validly existing and in good standing under the laws of the jurisdiction of its
incorporation or organization, with the requisite power and authority to own and use its properties and assets and to carry on
its business as currently conducted. Neither the Company nor any Subsidiary is in violation nor default of any of the provisions
of its respective certificate or articles of incorporation, bylaws or other organizational or charter documents. Each of the Company
and the Subsidiaries is duly qualified to conduct business and is in good standing as a foreign corporation or other entity in
each jurisdiction in which the nature of the business conducted or property owned by it makes such qualification necessary, except
where the failure to be so qualified or in good standing, as the case may be, could not have or reasonably be expected to result
in: (i) a material adverse effect on the legality, validity or enforceability of any Transaction Document, (ii) a material adverse
effect on the results of operations, assets, business, prospects or condition (financial or otherwise) of the Company and the Subsidiaries,
taken as a whole, or (iii) a material adverse effect on the Company’s ability to perform in any material respect on a timely
basis its obligations under any Transaction Document (any of (i), (ii) or (iii), a “Material Adverse Effect”) and no
Proceeding has been instituted in any such jurisdiction revoking, limiting or curtailing or seeking to revoke, limit or curtail
such power and authority or qualification.

 

(c)       Authorization;
Enforcement. The Company has the requisite corporate power and authority to enter into and to consummate the transactions contemplated
by this Agreement and each of the other Transaction Documents and otherwise to carry out its obligations hereunder and thereunder.
The execution and delivery of this Agreement and each of the other Transaction Documents by the Company and the consummation by
it of the transactions contemplated hereby and thereby have been duly authorized by all necessary action on the part of the Company
and no further action is required by the Company, the Board of Directors or the Company’s stockholders in connection herewith
or therewith other than in connection with the Required Approvals. This Agreement and each other Transaction Document to which
it is a party has been (or upon delivery will have been) duly executed by the Company and, when delivered in accordance with the
terms hereof and thereof, will constitute the valid and binding obligation of the Company enforceable against the Company in accordance
with its terms, except (i) as limited by general equitable principles and applicable bankruptcy, insolvency, reorganization, moratorium
and other laws of general application affecting enforcement of creditors’ rights generally, (ii) as limited by laws relating
to the availability of specific performance, injunctive relief or other equitable remedies and (iii) insofar as indemnification
and contribution provisions may be limited by applicable law.

 

(d)       No
Conflicts. The execution, delivery and performance by the Company of this Agreement and the other Transaction Documents to
which it is a party, the issuance and sale of the Securities and the consummation by it of the transactions contemplated hereby
and thereby do not and will not (i) conflict with or violate any provision of the Company’s or any Subsidiary’s certificate
or articles of incorporation, bylaws or other organizational or charter documents, or (ii) conflict with, or constitute a default
(or an event that with notice or lapse of time or both would become a default) under, result in the creation of any Lien upon any
of the properties or assets of the Company or any Subsidiary, or give to others any rights of termination, amendment, acceleration
or cancellation (with or without notice, lapse of time or both) of, any agreement, credit facility, debt or other instrument (evidencing
a Company or Subsidiary debt or otherwise) or other understanding to which the Company or any Subsidiary is a party or by which
any property or asset of the Company or any Subsidiary is bound or affected, or (iii) subject to the Required Approvals, conflict
with or result in a violation of any law, rule, regulation, order, judgment, injunction, decree or other restriction of any court
or governmental authority to which the Company or a Subsidiary is subject (including federal and state securities laws and regulations),
or by which any property or asset of the Company or a Subsidiary is bound or affected; except in the case of each of clauses (ii)
and (iii), such as could not have or reasonably be expected to result in a Material Adverse Effect.

 

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(e)       Filings,
Consents and Approvals. The Company is not required to obtain any consent, waiver, authorization or order of, give any notice
to, or make any filing or registration with, any court or other federal, state, local or other governmental authority or other
Person in connection with the execution, delivery and performance by the Company of the Transaction Documents, other than: (i)
the filings required pursuant to Section 4.4 of this Agreement, (ii) the filing with the Commission of the Prospectus Supplement,
(iii) application(s) to each applicable Trading Market for the listing of the Shares and Warrant Shares for trading thereon in
the time and manner required thereby and (iv) such filings as are required to be made under applicable state securities laws (collectively,
the “Required Approvals”).

 

(f)       Issuance
of the Securities; Registration. The Securities and Agent Wararnts are duly authorized and, when issued and paid for in accordance
with the applicable Transaction Documents, will be duly and validly issued, fully paid and nonassessable, free and clear of all
Liens imposed by the Company. The shares underlying the Warrants and the shares underlying the Agent Warrants (collectively, the
“Warrant Shares”) , when issued in accordance with the terms of the Warrants, will be validly issued, fully paid and
nonassessable, free and clear of all Liens imposed by the Company. The Company has reserved from its duly authorized capital stock
the maximum number of shares of Common Stock issuable pursuant to this Agreement and the Warrants. The Company has prepared and
filed the Registration Statement in conformity with the requirements of the Securities Act, which became effective on April 25,
2017 as to the initial registration statement (Registration File No. 333-216345) (the “Effective Date”), including
the Prospectus, and such amendments and supplements thereto as may have been required to the date of this Agreement. The Registration
Statement is effective under the Securities Act and no stop order preventing or suspending the effectiveness of the Registration
Statement or suspending or preventing the use of the Prospectus has been issued by the Commission and no proceedings for that
purpose have been instituted or, to the knowledge of the Company, are threatened by the Commission. The Company, if required by
the rules and regulations of the Commission, shall file the Prospectus with the Commission pursuant to Rule 424(b). At the time
the Registration Statement and any amendments thereto became effective, at the date of this Agreement and at the Closing Date,
the Registration Statement and any amendments thereto conformed and will conform in all material respects to the requirements
of the Securities Act and did not and will not contain any untrue statement of a material fact or omit to state any material fact
required to be stated therein or necessary to make the statements therein not misleading; and the Prospectus and any amendments
or supplements thereto, at time the Prospectus or any amendment or supplement thereto was issued and at the Closing Date, conformed
and will conform in all material respects to the requirements of the Securities Act and did not and will not contain an untrue
statement of a material fact or omit to state a material fact necessary in order to make the statements therein, in light of the
circumstances under which they were made, not misleading.

 

(g)       Capitalization.
The capitalization of the Company is as set forth on Schedule 3.1(g). The Company has not issued any capital stock since except
as disclosed in the SEC Reports as that term is defined in Section 3.1(h). under the Exchange Act, other than pursuant to the
exercise of employee stock options under the Company’s stock option plans, the issuance of shares of Common Stock to employees
pursuant to the Company’s employee stock purchase plans and pursuant to the conversion and/or exercise of Common Stock Equivalents
outstanding as of the date of the most recently filed report under the Exchange Act. No Person has any right of first refusal,
preemptive right, right of participation, or any similar right to participate in the transactions contemplated by the Transaction
Documents. Except as a result of the purchase and sale of the Securities, there are no outstanding options, warrants, scrip rights
to subscribe to, calls or commitments of any character whatsoever relating to, or securities, rights or obligations convertible
into or exercisable or exchangeable for, or giving any Person any right to subscribe for or acquire, any shares of Common Stock,
or contracts, commitments, understandings or arrangements by which the Company or any Subsidiary is or may become bound to issue
additional shares of Common Stock or Common Stock Equivalents. The issuance and sale of the Securities will not obligate the Company
to issue shares of Common Stock or other securities to any Person (other than the Purchasers) and will not result in a right of
any holder of Company securities to adjust the exercise, conversion, exchange or reset price under any of such securities. All
of the outstanding shares of capital stock of the Company are duly authorized, validly issued, fully paid and nonassessable, have
been issued in compliance with all federal and state securities laws, and none of such outstanding shares was issued in violation
of any preemptive rights or similar rights to subscribe for or purchase securities. No further approval or authorization of any
stockholder, the Board of Directors or others is required for the issuance and sale of the Securities. There are no stockholders
agreements, voting agreements or other similar agreements with respect to the Company’s capital stock to which the Company
is a party or, to the knowledge of the Company, between or among any of the Company’s stockholders.

 

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(h)       SEC
Reports; Financial Statements. The Company has filed all reports, schedules, forms, statements and other documents required
to be filed by the Company under the Securities Act and the Exchange Act, including pursuant to Section 13(a) or 15(d) thereof,
for the two years preceding the date hereof (or such shorter period as the Company was required by law or regulation to file such
material) (the foregoing materials, including the exhibits thereto and documents incorporated by reference therein, together with
the Prospectus and the Prospectus Supplement, being collectively referred to herein as the “SEC Reports”) on a timely
basis or has received a valid extension of such time of filing and has filed any such SEC Reports prior to the expiration of any
such extension. As of their respective dates, the SEC Reports complied in all material respects with the requirements of the Securities
Act and the Exchange Act, as applicable, and none of the SEC Reports, when filed, contained any untrue statement of a material
fact or omitted to state a material fact required to be stated therein or necessary in order to make the statements therein, in
the light of the circumstances under which they were made, not misleading. The Company has never been an issuer subject to Rule
144(i) under the Securities Act. The financial statements of the Company included in the SEC Reports comply in all material respects
with applicable accounting requirements and the rules and regulations of the Commission with respect thereto as in effect at the
time of filing. Such financial statements have been prepared in accordance with United States generally accepted accounting principles
applied on a consistent basis during the periods involved (“GAAP”), except as may be otherwise specified in such financial
statements or the notes thereto and except that unaudited financial statements may not contain all footnotes required by GAAP,
and fairly present in all material respects the financial position of the Company and its consolidated Subsidiaries as of and for
the dates thereof and the results of operations and cash flows for the periods then ended, subject, in the case of unaudited statements,
to normal, immaterial, year-end audit adjustments.

 

(i)       Material
Changes; Undisclosed Events, Liabilities or Developments. Since the date of the latest audited financial statements
included within the SEC Reports, except as specifically disclosed in a subsequent SEC Report filed prior to the date hereof,
(i) there has been no event, occurrence or development that has had or that could reasonably be expected to result in a
Material Adverse Effect, (ii) the Company has not incurred any liabilities (contingent or otherwise) other than (A) trade
payables and accrued expenses incurred in the ordinary course of business consistent with past practice and (B) liabilities
not required to be reflected in the Company’s financial statements pursuant to GAAP or disclosed in filings made with
the Commission, (iii) the Company has not altered its method of accounting, (iv) the Company has not declared or made any
dividend or distribution of cash or other property to its stockholders or purchased, redeemed or made any agreements to
purchase or redeem any shares of its capital stock and (v) the Company has not issued any equity securities to any officer,
director or Affiliate, except pursuant to existing Company stock option plans. The Company does not have pending before the
Commission any request for confidential treatment of information. Except for the issuance of the Securities contemplated by
this Agreement or as set forth on Schedule 3.1(i), no event, liability, fact, circumstance, occurrence or development has
occurred or exists or is reasonably expected to occur or exist with respect to the Company or its Subsidiaries or their
respective businesses, prospects, properties, operations, assets or financial condition that would be required to be
disclosed by the Company under applicable securities laws at the time this representation is made or deemed made that has not
been publicly disclosed at least 1 Trading Day prior to the date that this representation is made.

 

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(j)       Litigation.
There is no action, suit, inquiry, notice of violation, proceeding or investigation pending or, to the knowledge of the Company,
threatened against or affecting the Company, any Subsidiary or any of their respective properties before or by any court, arbitrator,
governmental or administrative agency or regulatory authority (federal, state, county, local or foreign) (collectively, an “Action”)
which (i) adversely affects or challenges the legality, validity or enforceability of any of the Transaction Documents or the Securities
or (ii) could, if there were an unfavorable decision, have or reasonably be expected to result in a Material Adverse Effect. Neither
the Company nor any Subsidiary, nor any director or officer thereof, is or has been the subject of any Action involving a claim
of violation of or liability under federal or state securities laws or a claim of breach of fiduciary duty. There has not been,
and to the knowledge of the Company, there is not pending or contemplated, any investigation by the Commission involving the Company
or any current or former director or officer of the Company. The Commission has not issued any stop order or other order suspending
the effectiveness of any registration statement filed by the Company or any Subsidiary under the Exchange Act or the Securities
Act. 

 

(k)       Labor
Relations. No labor dispute exists or, to the knowledge of the Company, is imminent with respect to any of the employees of
the Company, which could reasonably be expected to result in a Material Adverse Effect. None of the Company’s or its Subsidiaries’
employees is a member of a union that relates to such employee’s relationship with the Company or such Subsidiary, and neither
the Company nor any of its Subsidiaries is a party to a collective bargaining agreement, and the Company and its Subsidiaries believe
that their relationships with their employees are good. To the knowledge of the Company, no executive officer of the Company or
any Subsidiary, is, or is now expected to be, in violation of any material term of any employment contract, confidentiality, disclosure
or proprietary information agreement or non-competition agreement, or any other contract or agreement or any restrictive covenant
in favor of any third party, and the continued employment of each such executive officer does not subject the Company or any of
its Subsidiaries to any liability with respect to any of the foregoing matters. The Company and its Subsidiaries are in compliance
with all U.S. federal, state, local and foreign laws and regulations relating to employment and employment practices, terms and
conditions of employment and wages and hours, except where the failure to be in compliance could not, individually or in the aggregate,
reasonably be expected to have a Material Adverse Effect.

 

(l)       Compliance.
The Company is not: (i) in default under or in violation of (and no event has occurred that has not been waived that, with notice
or lapse of time or both, would result in a default by the Company or any Subsidiary under), nor has the Company or any Subsidiary
received notice of a claim that it is in default under or that it is in violation of, any indenture, loan or credit agreement or
any other agreement or instrument to which it is a party or by which it or any of its properties is bound (whether or not such
default or violation has been waived), (ii) in violation of any judgment, decree or order of any court, arbitrator or other governmental
authority or (iii) in violation of any statute, rule, ordinance or regulation of any governmental authority, including without
limitation all foreign, federal, state and local laws relating to taxes, environmental protection, occupational health and safety,
product quality and safety and employment and labor matters, except in each case as could not have or reasonably be expected to
result in a Material Adverse Effect.

 

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(m)       Regulatory
Permits. The Company and the Subsidiaries possess all certificates, authorizations and permits issued by the appropriate federal,
state, local or foreign regulatory authorities necessary to conduct their respective businesses as described in the SEC Reports,
except where the failure to possess such permits could not reasonably be expected to result in a Material Adverse Effect (“Material
Permits”), and neither the Company nor any Subsidiary has received any notice of proceedings relating to the revocation or
modification of any Material Permit.

 

(n)       Title
to Assets. The Company and the Subsidiaries have good and marketable title in fee simple to all real property owned by them
and good and marketable title in all personal property owned by them that is material to the business of the Company and the Subsidiaries,
in each case free and clear of all Liens, except for (i) Liens as do not materially affect the value of such property and do not
materially interfere with the use made and proposed to be made of such property by the Company and the Subsidiaries and (ii) Liens
for the payment of federal, state or other taxes, for which appropriate reserves have been made in accordance with GAAP and, the
payment of which is neither delinquent nor subject to penalties. Any real property and facilities held under lease by the Company
and the Subsidiaries are held by them under valid, subsisting and enforceable leases with which the Company and the Subsidiaries
are in compliance.

 

(o)       Intellectual
Property. The Company and the Subsidiaries have, or have rights to use, all patents, patent applications, trademarks, trademark
applications, service marks, trade names, trade secrets, inventions, copyrights, licenses and other intellectual property rights
and similar rights necessary or required for use in connection with their respective businesses as described in the SEC Reports
and which the failure to so have could have a Material Adverse Effect (collectively, the “Intellectual Property Rights”).
None of, and neither the Company nor any Subsidiary has received a notice (written or otherwise) that any of, the Intellectual
Property Rights has expired, terminated or been abandoned, or is essential for the Company’s business and is expected to
expire or terminate or be abandoned, within two (2) years from the date of this Agreement. Neither the Company nor any Subsidiary
has received, since the date of the latest audited financial statements included within the SEC Reports, a written notice of a
claim or otherwise has any knowledge that the Intellectual Property Rights violate or infringe upon the rights of any Person, except
as could not have or reasonably be expected to not have a Material Adverse Effect. To the knowledge of the Company, all such Intellectual
Property Rights are enforceable and there is no existing infringement by another Person of any of the Intellectual Property Rights.
The Company and its Subsidiaries have taken reasonable security measures to protect the secrecy, confidentiality and value of all
of their intellectual properties, except where failure to do so could not, individually or in the aggregate, reasonably be expected
to have a Material Adverse Effect.

 

(p)       Insurance.
The Company and the Subsidiaries are insured by insurers of recognized financial responsibility against such losses and risks and
in such amounts as are prudent and customary in the businesses in which the Company is engaged, including, but not limited to,
directors and officers insurance coverage at least equal to the aggregate Subscription Amount. Neither the Company nor any Subsidiary
has any reason to believe that it will not be able to renew its existing insurance coverage as and when such coverage expires or
to obtain similar coverage from similar insurers as may be necessary to continue its business without a significant increase in
cost.

 

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(q)       Transactions
With Affiliates and Employees. Except as set forth in the SEC Reports, none of the officers or directors of the Company or
any Subsidiary and, to the knowledge of the Company, none of the employees of the Company or any Subsidiary is presently a party
to any transaction with the Company or any Subsidiary (other than for services as employees, officers and directors), including
any contract, agreement or other arrangement providing for the furnishing of services to or by, providing for rental of real or
personal property to or from, providing for the borrowing of money from or lending of money to or otherwise requiring payments
to or from any officer, director or such employee or, to the knowledge of the Company, any entity in which any officer, director,
or any such employee has a substantial interest or is an officer, director, trustee, stockholder, member or partner, in each case
in excess of $120,000 other than for (i) payment of salary or consulting fees for services rendered, (ii) reimbursement for expenses
incurred on behalf of the Company and (iii) other employee benefits, including stock option agreements under any stock option plan
of the Company.

 

(r)       Sarbanes-Oxley;
Internal Accounting Controls. The Company and the Subsidiaries are in compliance with any and all applicable requirements of
the Sarbanes-Oxley Act of 2002 that are effective as of the date hereof, and any and all applicable rules and regulations promulgated
by the Commission thereunder that are effective as of the date hereof and as of the Closing Date. Except as set forth in the SEC
Reports, the Company and the Subsidiaries maintain a system of internal accounting controls sufficient to provide reasonable assurance
that: (i) transactions are executed in accordance with management’s general or specific authorizations, (ii) transactions
are recorded as necessary to permit preparation of financial statements in conformity with GAAP and to maintain asset accountability,
(iii) access to assets is permitted only in accordance with management’s general or specific authorization, and (iv) the
recorded accountability for assets is compared with the existing assets at reasonable intervals and appropriate action is taken
with respect to any differences. Except as set forth in the SEC Reports, the Company and the Subsidiaries have established disclosure
controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) for the Company and the Subsidiaries and designed
such disclosure controls and procedures to ensure that information required to be disclosed by the Company in the reports it files
or submits under the Exchange Act is recorded, processed, summarized and reported, within the time periods specified in the Commission’s
rules and forms. The Company’s certifying officers have evaluated the effectiveness of the disclosure controls and procedures
of the Company and the Subsidiaries as of the end of the period covered by the most recently filed periodic report under the Exchange
Act (such date, the “Evaluation Date”). The Company presented in its most recently filed periodic report under the
Exchange Act the conclusions of the certifying officers about the effectiveness of the disclosure controls and procedures based
on their evaluations as of the Evaluation Date. Since the Evaluation Date, there have been no changes in the internal control over
financial reporting (as such term is defined in the Exchange Act) of the Company and its Subsidiaries that have materially affected,
or is reasonably likely to materially affect, the internal control over financial reporting of the Company and its Subsidiaries.

 

(s)       Certain
Fees. Except for a fee payable to Chardan and [ ] as set forth in the Prospectus Supplement, no brokerage or finder’s
fees or commissions are or will be payable by the Company to any broker, financial advisor or consultant, finder, placement agent,
investment banker, bank or other Person with respect to the transactions contemplated by the Transaction Documents. The Purchasers
shall have no obligation with respect to any fees or with respect to any claims made by or on behalf of other Persons for fees
of a type contemplated in this Section that may be due in connection with the transactions contemplated by the Transaction Documents.

 

    	 	9	 

     

    

 

(t)       Investment
Company. The Company is not, and is not an Affiliate of, and immediately after receipt of payment for the Securities, will
not be or be an Affiliate of, an “investment company” within the meaning of the Investment Company Act of 1940, as
amended. The Company shall conduct its business in a manner so that it will not become an “investment company” subject
to registration under the Investment Company Act of 1940, as amended.

 

(u)       Registration
Rights. No Person has any right to cause the Company to effect the registration under the Securities Act of any securities
of the Company.

 

(v)       Listing
and Maintenance Requirements. The Common Stock is registered pursuant to Section 12(b) or 12(g) of the Exchange Act, and the
Company has taken no action designed to, or which to its knowledge is likely to have the effect of, terminating the registration
of the Common Stock under the Exchange Act nor has the Company received any notification that the Commission is contemplating terminating
such registration. The Company has not, in the 12 months preceding the date hereof, received notice from any Trading Market on
which the Common Stock is or has been listed or quoted to the effect that the Company is not in compliance with the listing or
maintenance requirements of such Trading Market. The Company is, and has no reason to believe that it will not in the foreseeable
future continue to be, in compliance with all such listing and maintenance requirements.

 

(w)       Application
of Takeover Protections. The Company and the Board of Directors have taken all necessary action, if any, in order to render
inapplicable any control share acquisition, business combination, poison pill (including any distribution under a rights agreement)
or other similar anti-takeover provision under the Company’s certificate of incorporation (or similar charter documents)
or the laws of its state of incorporation that is or could become applicable to the Purchasers as a result of the Purchasers and
the Company fulfilling their obligations or exercising their rights under the Transaction Documents, including without limitation
as a result of the Company’s issuance of the Securities and the Purchasers’ ownership of the Securities.

 

(x)       Disclosure.
Except with respect to the material terms and conditions of the transactions contemplated by the Transaction Documents, the Company
confirms that neither it nor any other Person acting on its behalf has provided any of the Purchasers or their agents or counsel
with any information that it believes constitutes or might constitute material, non-public information which is not otherwise disclosed
in the Prospectus Supplement. The Company understands and confirms that the Purchasers will rely on the foregoing representation
in effecting transactions in securities of the Company. All of the disclosure furnished by or on behalf of the Company to the Purchasers
regarding the Company and its Subsidiaries, their respective businesses and the transactions contemplated hereby, including the
Disclosure Schedules to this Agreement, is true and correct and does not contain any untrue statement of a material fact or omit
to state any material fact necessary in order to make the statements made therein, in light of the circumstances under which they
were made, not misleading. The press releases disseminated by the Company during the twelve months preceding the date of this Agreement
taken as a whole do not contain any untrue statement of a material fact or omit to state a material fact required to be stated
therein or necessary in order to make the statements therein, in light of the circumstances under which they were made and when
made, not misleading. The Company acknowledges and agrees that no Purchaser makes or has made any representations or warranties
with respect to the transactions contemplated hereby other than those specifically set forth in Section 3.2 hereof.

 

(y)       No
Integrated Offering. Assuming the accuracy of the Purchasers’ representations and warranties set forth in Section 3.2,
neither the Company, nor any of its Affiliates, nor any Person acting on its or their behalf has, directly or indirectly, made
any offers or sales of any security or solicited any offers to buy any security, under circumstances that would cause this offering
of the Securities to be integrated with prior offerings by the Company for purposes of any applicable shareholder approval provisions
of any Trading Market on which any of the securities of the Company are listed or designated.

 

    	 	10	 

     

    

 

(z)
       Debts. The Company does not intend to incur debts beyond its ability to pay such
debts as they mature (taking into account the timing and amounts of cash to be payable on or in respect of its debt). The Company
has no knowledge of any facts or circumstances which lead it to believe that it will file for reorganization or liquidation under
the bankruptcy or reorganization laws of any jurisdiction within one year from the Closing Date. Schedule 3.1(z) sets forth as
of the date hereof all outstanding secured and unsecured Indebtedness of the Company or any Subsidiary, or for which the Company
or any Subsidiary has commitments. For the purposes of this Agreement, “Indebtedness” means (x) any liabilities for
borrowed money or amounts owed in excess of $50,000 (other than trade accounts payable incurred in the ordinary course of business),
(y) all guaranties, endorsements and other contingent obligations in respect of indebtedness of others, whether or not the same
are or should be reflected in the Company’s consolidated balance sheet (or the notes thereto), except guaranties by endorsement
of negotiable instruments for deposit or collection or similar transactions in the ordinary course of business; and (z) the present
value of any lease payments in excess of $50,000 due under leases required to be capitalized in accordance with GAAP. Neither the
Company nor any Subsidiary is in default with respect to any Indebtedness.

 

(aa)      Tax
Status. Except for matters that would not, individually or in the aggregate, have or reasonably be expected to result in a
Material Adverse Effect, the Company and its Subsidiaries each (i) has made or filed all United States federal, state and local
income and all foreign income and franchise tax returns, reports and declarations required by any jurisdiction to which it is subject,
(ii) has paid all taxes and other governmental assessments and charges that are material in amount, shown or determined to be due
on such returns, reports and declarations and (iii) has set aside on its books provision reasonably adequate for the payment of
all material taxes for periods subsequent to the periods to which such returns, reports or declarations apply. There are no unpaid
taxes in any material amount claimed to be due by the taxing authority of any jurisdiction, and the officers of the Company or
of any Subsidiary know of no basis for any such claim.

 

(bb)      Foreign
Corrupt Practices. Neither the Company nor any Subsidiary, nor to the knowledge of the Company or any Subsidiary, any agent
or other person acting on behalf of the Company or any Subsidiary, has (i) directly or indirectly, used any funds for unlawful
contributions, gifts, entertainment or other unlawful expenses related to foreign or domestic political activity, (ii) made any
unlawful payment to foreign or domestic government officials or employees or to any foreign or domestic political parties or campaigns
from corporate funds, (iii) failed to disclose fully any contribution made by the Company or any Subsidiary (or made by any person
acting on its behalf of which the Company is aware) which is in violation of law, or (iv) violated in any material respect any
provision of FCPA.

 

(cc)      Accountants.
The Company’s accounting firm is set forth on Schedule 3.1(cc) of the Disclosure Schedules. To the knowledge and belief of
the Company, such accounting firm (i) is a registered public accounting firm as required by the Exchange Act and (ii) shall express
its opinion with respect to the financial statements to be included in the Company’s Annual Report for the fiscal year ended
June 30, 2018.

 

    	 	11	 

     

    

 

(dd)     Acknowledgment Regarding Purchasers’ Purchase of Securities. The Company acknowledges and agrees that each of the
Purchasers is acting solely in the capacity of an arm’s length purchaser with respect to the Transaction Documents and the
transactions contemplated thereby. The Company further acknowledges that no Purchaser is acting as a financial advisor or fiduciary
of the Company (or in any similar capacity) with respect to the Transaction Documents and the transactions contemplated thereby
and any advice given by any Purchaser or any of their respective representatives or agents in connection with the Transaction Documents
and the transactions contemplated thereby is merely incidental to the Purchasers’ purchase of the Securities. The Company
further represents to each Purchaser that the Company’s decision to enter into this Agreement and the other Transaction Documents
has been based solely on the independent evaluation of the transactions contemplated hereby by the Company and its representatives.

 

(ee)      Acknowledgement
Regarding Purchaser’s Trading Activity. Anything in this Agreement or elsewhere herein to the contrary notwithstanding
(except for Sections 3.2(e) and 4.14 hereof), it is understood and acknowledged by the Company that: (i) none of the Purchasers
has been asked by the Company to agree, nor has any Purchaser agreed, to desist from purchasing or selling, long and/or short,
securities of the Company, or “derivative” securities based on securities issued by the Company or to hold the Securities
for any specified term; (ii) past or future open market or other transactions by any Purchaser, specifically including, without
limitation, Short Sales or “derivative” transactions, before or after the closing of this or future private placement
transactions, may negatively impact the market price of the Company’s publicly-traded securities; (iii) any Purchaser, and
counter-parties in “derivative” transactions to which any such Purchaser is a party, directly or indirectly, presently
may have a “short” position in the Common Stock, and (iv) each Purchaser shall not be deemed to have any affiliation
with or control over any arm’s length counter-party in any “derivative” transaction. The Company further understands
and acknowledges that (y) one or more Purchasers may engage in hedging activities at various times during the period that the Securities
are outstanding, including, without limitation, during the periods that the value of the Warrant Shares deliverable with respect
to Securities are being determined, and (z) such hedging activities (if any) could reduce the value of the existing stockholders'
equity interests in the Company at and after the time that the hedging activities are being conducted. The Company acknowledges
that such aforementioned hedging activities do not constitute a breach of any of the Transaction Documents.

 

(ff)        Regulation
M Compliance. The Company has not, and to its knowledge no one acting on its behalf has, (i) taken, directly or indirectly,
any action designed to cause or to result in the stabilization or manipulation of the price of any security of the Company to facilitate
the sale or resale of any of the Securities, (ii) sold, bid for, purchased, or, paid any compensation for soliciting purchases
of, any of the Securities, or (iii) paid or agreed to pay to any Person any compensation for soliciting another to purchase any
other securities of the Company, other than, in the case of clauses (ii) and (iii), compensation paid to the Company’s placement
agent in connection with the placement of the Securities.

 

(gg)     Office
of Foreign Assets Control. Neither the Company nor any Subsidiary nor, to the Company's knowledge, any director, officer, agent,
employee or affiliate of the Company or any Subsidiary is currently subject to any U.S. sanctions administered by the Office of
Foreign Assets Control of the U.S. Treasury Department (“OFAC”).

 

(hh)      U.S.
Real Property Holding Corporation. The Company is not and has never been a U.S. real property holding corporation within the
meaning of Section 897 of the Internal Revenue Code of 1986, as amended, and the Company shall so certify upon Purchaser’s
request.

 

(ii)        Bank
Holding Company Act. Neither the Company nor any of its Subsidiaries or Affiliates is subject to the Bank Holding Company Act
of 1956, as amended (the “BHCA”) and to regulation by the Board of Governors of the Federal Reserve System (the “Federal
Reserve”). Neither the Company nor any of its Subsidiaries or Affiliates owns or controls, directly or indirectly, five percent
(5%) or more of the outstanding shares of any class of voting securities or twenty-five percent or more of the total equity of
a bank or any entity that is subject to the BHCA and to regulation by the Federal Reserve. Neither the Company nor any of its Subsidiaries
or Affiliates exercises a controlling influence over the management or policies of a bank or any entity that is subject to the
BHCA and to regulation by the Federal Reserve.

 

    	 	12	 

     

    

 

(jj)        Money
Laundering. The operations of the Company and its Subsidiaries are and have been conducted at all times in compliance with
applicable financial record-keeping and reporting requirements of the Currency and Foreign Transactions Reporting Act of 1970,
as amended, applicable money laundering statutes and applicable rules and regulations thereunder (collectively, the “Money
Laundering Laws”), and no action, suit or proceeding by or before any court or governmental agency, authority or body or
any arbitrator involving the Company or any Subsidiary with respect to the Money Laundering Laws is pending or, to the knowledge
of the Company or any Subsidiary, threatened.

 

SECTION 4.        ENGAGEMENT TERM.
Placement Agent’s engagement hereunder will be for the period of 10 days. Notwithstanding anything to the contrary contained
herein, the provisions concerning confidentiality, indemnification and contribution contained herein and the Company’s obligations
contained in the Indemnification Provisions will survive any expiration or termination of this Agreement, and the Company’s
obligation to pay fees actually earned and payable pursuant to Section 1 hereof, will survive any expiration or termination of
this Agreement. Placement Agent agrees not to use any confidential information concerning the Company provided to them by the Company
for any purposes other than those contemplated under this Agreement.

 

SECTION 5.         PLACEMENT AGENT’S
INFORMATION. The Company agrees that any information or advice rendered by the Placement Agent in connection with this engagement
is for the confidential use of the Company only in their evaluation of the Placement and, except as otherwise required by law,
the Company will not disclose or otherwise refer to the advice or information in any manner without the Placement Agent’
prior written consent.

 

SECTION 6.         NO FIDUCIARY RELATIONSHIP.
This Agreement does not create, and shall not be construed as creating rights enforceable by any person or entity not a party hereto,
except those entitled hereto by virtue of the indemnification provisions hereof. The Company acknowledges and agrees that the Placement
Agent are not and shall not be construed as a fiduciary of the Company and shall have no duties or liabilities to the equity holders
or the creditors of the Company or any other person by virtue of this Agreement or the retention of the Placement Agent hereunder,
all of which are hereby expressly waived.

 

SECTION 7.         CLOSING. The
obligations of the Placement Agent and the Purchasers, and the closing of the sale of the Securities hereunder are subject to the
accuracy, when made and on the Closing Date, of the representations and warranties on the part of the Company and its Subsidiaries
contained herein, to the accuracy of the statements of the Company and its Subsidiaries made in any certificates pursuant to the
provisions hereof, to the performance by the Company and its Subsidiaries of their obligations hereunder, and to each of the following
additional terms and conditions:

 

(A)         No
stop order suspending the effectiveness of the Registration Statement shall have been issued and no proceedings for that purpose
shall have been initiated or threatened by the Commission, and any request for additional information on the part of the Commission
(to be included in the Registration Statement, the Base Prospectus or the Prospectus Supplement or otherwise) shall have been complied
with to the reasonable satisfaction of the Placement Agent.

 

    	 	13	 

     

    

 

(B)          The
Placement Agent shall not have discovered and disclosed to the Company on or prior to the Closing Date that the Registration Statement,
the Base Prospectus or the Prospectus Supplement or any amendment or supplement thereto contains an untrue statement of a fact
which, in the opinion of counsel for the Placement Agent, is material or omits to state any fact which, in the opinion of such
counsel, is material and is required to be stated therein or is necessary to make the statements therein not misleading.

 

(C)         All
corporate proceedings and other legal matters incident to the authorization, form, execution, delivery and validity of each of
this Agreement, the Securities, the Registration Statement, the Base Prospectus and the Prospectus Supplement and all other legal
matters relating to this Agreement and the transactions contemplated hereby shall be reasonably satisfactory in all material respects
to counsel for the Placement Agent, and the Company shall have furnished to such counsel all documents and information that they
may reasonably request to enable them to pass upon such matters.

 

(D)         The
Placement Agent shall have received from outside counsel to the Company such counsel’s written opinion, addressed to the
Placement Agent and the Purchasers dated as of the Closing Date, in form and substance reasonably satisfactory to the Placement
Agent, which opinion shall include a “10b-5” representation from such counsel.

 

(E)          Neither
the Company nor any of its Subsidiaries shall have sustained since the date of the latest audited financial statements included
or incorporated by reference in the Base Prospectus, any loss or interference with its business from fire, explosion, flood, terrorist
act or other calamity, whether or not covered by insurance, or from any labor dispute or court or governmental action, order or
decree, otherwise than as set forth in or contemplated by the Base Prospectus and (ii) since such date there shall not have been
any change in the capital stock or long-term debt of the Company or any of its Subsidiaries or any change, or any development involving
a prospective change, in or affecting the business, general affairs, management, financial position, stockholders’ equity,
results of operations or prospects of the Company and its Subsidiaries, otherwise than as set forth in or contemplated by the Base
Prospectus, the effect of which, in any such case described in clause (i) or (ii), is, in the judgment of the Placement Agent,
so material and adverse as to make it impracticable or inadvisable to proceed with the sale or delivery of the Securities on the
terms and in the manner contemplated by the Base Prospectus, the Time of Sale Prospectus, if any, and the Prospectus Supplement.

 

(F)          The
Common Stock is registered under the Exchange Act and, as of the Closing Date, the Shares shall be listed and admitted and authorized
for trading on the Trading Market, and satisfactory evidence of such actions shall have been provided to the Placement Agent. The
Company shall have taken no action designed to, or likely to have the effect of terminating the registration of the Common Stock
under the Exchange Act or delisting or suspending from trading the Common Stock from the Trading Market, nor has the Company received
any information suggesting that the Commission or the Trading Market is contemplating terminating such registration or listing.

 

(G)         Subsequent
to the execution and delivery of this Agreement, and prior to the expiration of its term, there shall not have occurred any of
the following: (i) trading in securities generally on the New York Stock Exchange, the Nasdaq National Market or the NYSE Alternext
US or in the over-the-counter market, or trading in any securities of the Company on any exchange or in the over-the-counter market,
shall have been suspended or minimum or maximum prices or maximum ranges for prices shall have been established on any such exchange
or such market by the Commission, by such exchange or by any other regulatory body or governmental authority having jurisdiction,
(ii) a banking moratorium shall have been declared by federal or state authorities or a material disruption has occurred in commercial
banking or securities settlement or clearance services in the United States, (iii) the United States shall have become engaged
in hostilities in which it is not currently engaged (excluding military or other action against the Syrian Arab Republic), the
subject of an act of terrorism, there shall have been an escalation in hostilities involving the United States, or there shall
have been a declaration of a national emergency or war by the United States, or (iv) there shall have occurred any other calamity
or crisis or any change in general economic, political or financial conditions in the United States or elsewhere, if the effect
of any such event in clause (iii) or (iv) makes it, in the sole judgment of the Placement Agent, impracticable or inadvisable to
proceed with the sale or delivery of the Securities on the terms and in the manner contemplated by the Base Prospectus and the
Prospectus Supplement.

 

    	 	14	 

     

    

 

(H)          No
action shall have been taken and no statute, rule, regulation or order shall have been enacted, adopted or issued by any governmental
agency or body which would, as of the Closing Date, prevent the issuance or sale of the Securities or materially and adversely
affect or potentially and adversely affect the business or operations of the Company; and no injunction, restraining order or order
of any other nature by any federal or state court of competent jurisdiction shall have been issued as of the Closing Date which
would prevent the issuance or sale of the Securities or materially and adversely affect or potentially and adversely affect the
business or operations of the Company.

 

(I)           The
Company shall have prepared and filed with the Commission a Current Report on Form 8-K with respect to the Placement, including
as an exhibit thereto this Agreement.

 

(J)          The
Company shall have entered into subscription agreements with each of the Purchasers and such agreements shall be in full force
and effect and shall contain representations and warranties of the Company as agreed between the Company and the Purchasers.

 

(K)         FINRA
shall have raised no objection to the fairness and reasonableness of the terms and arrangements of this Agreement. In addition,
the Company shall, if requested by the Placement Agent, make or authorize Placement Agent’s counsel to make on the Company’s
behalf, an Issuer Filing with FINRA pursuant to FINRA Rule 5110 with respect to the Registration Statement and pay all filing fees
required in connection therewith.

 

(L)          Prior
to the Closing Date, the Company shall have furnished to the Placement Agent such further information, certificates and documents
as the Placement Agent may reasonably request.

 

All opinions, letters,
evidence and certificates mentioned above or elsewhere in this Agreement shall be deemed to be in compliance with the provisions
hereof only if they are in form and substance reasonably satisfactory to counsel for the Placement Agent.

 

SECTION 8.         INDEMNIFICATION.(A)
To the extent permitted by law, the Company will indemnify the Placement Agent and its affiliates, stockholders, directors, officers,
employees and controlling persons (within the meaning of Section 15 of the Securities Act or Section 20 of the Exchange Act) against
all losses, claims, damages, expenses and liabilities, as the same are incurred (including the reasonable fees and expenses of
counsel), relating to or arising out of its activities hereunder or pursuant to this engagement letter, except to the extent that
any losses, claims, damages, expenses or liabilities (or actions in respect thereof) are found in a final judgment (not subject
to appeal) by a court of law to have resulted primarily and directly from Placement Agent’s willful misconduct or gross negligence
in performing the services described herein.

 

    	 	15	 

     

    

 

(B)         Promptly
after receipt by the Placement Agent of notice of any claim or the commencement of any action or proceeding with respect to which
Placement Agent is entitled to indemnity hereunder, the Placement Agent will notify the Company in writing of such claim or of
the commencement of such action or proceeding, and the Company will assume the defense of such action or proceeding and will employ
counsel reasonably satisfactory to the Placement Agent and will pay the fees and expenses of such counsel. Notwithstanding the
preceding sentence, the Placement Agent will be entitled to employ counsel separate from counsel for the Company and from any other
party in such action if counsel for the Placement Agent reasonably determines that it would be inappropriate under the applicable
rules of professional responsibility for the same counsel to represent both the Company and the Placement Agent. In such event,
the reasonable fees and disbursements of no more than one such separate counsel will be paid by the Company. The Company will have
the exclusive right to settle the claim or proceeding provided that the Company will not settle any such claim, action or proceeding
without the prior written consent of the Placement Agent, which will not be unreasonably withheld.

 

(C)         The
Company agrees to notify the Placement Agent promptly of the assertion against it or any other person of any claim or the commencement
of any action or proceeding relating to a transaction contemplated by this engagement letter.

 

(D)         If
for any reason the foregoing indemnity is unavailable to the Placement Agent or insufficient to hold the Placement Agent harmless,
then the Company shall contribute to the amount paid or payable by the Placement Agent as a result of such losses, claims, damages
or liabilities in such proportion as is appropriate to reflect not only the relative benefits received by the Company on the one
hand and the Placement Agent on the other, but also the relative fault of the Company on the one hand and the Placement Agent on
the other that resulted in such losses, claims, damages or liabilities, as well as any relevant equitable considerations. The amounts
paid or payable by a party in respect of losses, claims, damages and liabilities referred to above shall be deemed to include any
legal or other fees and expenses incurred in defending any litigation, proceeding or other action or claim. Notwithstanding the
provisions hereof, the Placement Agent’s share of the liability hereunder shall not be in excess of the amount of fees actually
received, or to be received, by the Placement Agent under this engagement letter (excluding any amounts received as reimbursement
of expenses incurred by the Placement Agent).

 

(E)         These
indemnification provisions shall remain in full force and effect whether or not the transaction contemplated by this engagement
letter is completed and shall survive the termination of this engagement letter, and shall be in addition to any liability that
the Company might otherwise have to any indemnified party under this engagement letter or otherwise.

 

SECTION 9.         GOVERNING LAW.
This Agreement will be governed by, and construed in accordance with, the laws of the State of New York applicable to agreements
made and to be performed entirely in such State. This Agreement may not be assigned by either party without the prior written consent
of the other party. This Agreement shall be binding upon and inure to the benefit of the parties hereto, and their respective successors
and permitted assigns. Any right to trial by jury with respect to any dispute arising under this Agreement or any transaction or
conduct in connection herewith is waived. Any dispute arising under this Agreement may be brought into the courts of the State
of New York or into the Federal Court located in New York, New York and, by execution and delivery of this Agreement, the Company
hereby accepts for itself and in respect of its property, generally and unconditionally, the jurisdiction of aforesaid courts.
Each party hereto hereby irrevocably waives personal service of process and consents to process being served in any such suit,
action or proceeding by delivering a copy thereof via overnight delivery (with evidence of delivery) to such party at the address
in effect for notices to it under this Agreement and agrees that such service shall constitute good and sufficient service of process
and notice thereof. Nothing contained herein shall be deemed to limit in any way any right to serve process in any manner permitted
by law. If either party shall commence an action or proceeding to enforce any provisions of a Transaction Document, then the prevailing
party in such action or proceeding shall be reimbursed by the other party for its attorneys fees and other costs and expenses incurred
with the investigation, preparation and prosecution of such action or proceeding.

 

    	 	16	 

     

    

 

SECTION 10.       ENTIRE AGREEMENT/MISC.
This Agreement (including the attached Indemnification Provisions) embodies the entire agreement and understanding between the
parties hereto, and supersedes all prior agreements and understandings, relating to the subject matter hereof. If any provision
of this Agreement is determined to be invalid or unenforceable in any respect, such determination will not affect such provision
in any other respect or any other provision of this Agreement, which will remain in full force and effect. This Agreement may not
be amended or otherwise modified or waived except by an instrument in writing signed by both Placement Agent and the Company. The
representations, warranties, agreements and covenants contained herein shall survive the closing of the Placement and delivery
and/or exercise of the Securities, as applicable. This Agreement may be executed in two or more counterparts, all of which when
taken together shall be considered one and the same agreement and shall become effective when counterparts have been signed by
each party and delivered to the other party, it being understood that both parties need not sign the same counterpart. In the event
that any signature is delivered by facsimile transmission or a .pdf format file, such signature shall create a valid and binding
obligation of the party executing (or on whose behalf such signature is executed) with the same force and effect as if such facsimile
or .pdf signature page were an original thereof.

 

SECTION 11.       NOTICES. Any
and all notices or other communications or deliveries required or permitted to be provided hereunder shall be in writing and shall
be deemed given and effective on the earliest of (a) the date of transmission, if such notice or communication is delivered via
facsimile at the facsimile number specified on the signature pages attached hereto prior to 6:30 p.m. (New York City time) on a
business day, (b) the next business day after the date of transmission, if such notice or communication is delivered via facsimile
at the facsimile number on the signature pages attached hereto on a day that is not a business day or later than 6:30 p.m. (New
York City time) on any business day, (c) the business day following the date of mailing, if sent by U.S. nationally recognized
overnight courier service, or (d) upon actual receipt by the party to whom such notice is required to be given. The address for
such notices and communications shall be as set forth on the signature pages hereto.

 

********************

 

    	 	17	 

     

    

 

Please confirm that
the foregoing correctly sets forth our agreement by signing and returning to the Placement Agent a copy of this Agreement.

 

	 	Very truly yours
	 	 
	 	CHARDAN CAPITAL MARKETS, LLC
	 	 
	 	By: 	
	 	Name:
	 	Title:
	 	 
	 	Address for notice:
	 	17 State Street, Suite 1600
	 	New York, New York 10004
	 	 
	 	[                 ],
    LLC
	 	 
	 	By:  	 
	 	Name:
	 	Title:
	 	 
	 	Address for notice:

 

	Accepted and Agreed to as of	 
	the date first written above:	 
	 	 
	NANOVIRICIDES, INC.	 

 

	By:	 	 

	Name:  Dr. Anil Diwan	 
	Title:   President	 

 

	Address for notice:	 
	 	 
	NanoViricides, Inc.	 
	1 Controls Drive	 
	Shelton, CT 06484	 

 

    	 	18EX-4.2

 Exhibit 4.2 
  

 
 FIRST SUPPLEMENTAL INDENTURE 

among 
 TELEFÓNICA
EMISIONES, S.A.U., 
 as Issuer, 

TELEFÓNICA, S.A.,  

as Guarantor 
 and

 THE BANK OF NEW YORK MELLON,  

as Trustee, Transfer Agent, Registrar and Paying Agent 

March 1, 2019 

$1,250,000,000 
 FIXED RATE SENIOR
NOTES DUE 2049 
  
  

  

 TABLE OF CONTENTS 

 

							
	 	  	 	  	PAGE	 
	ARTICLE 1	 
	DEFINITIONS AND OTHER PROVISIONS OF GENERAL APPLICATION	 
	 Section 1.01.
	  	Definitions	  	 	1	 
	 Section 1.02.
	  	Conflict with Trust Indenture Act	  	 	3	 
	 Section 1.03.
	  	Effect of Headings and Table of Contents	  	 	3	 
	 Section 1.04.
	  	Successors and Assigns	  	 	3	 
	 Section 1.05.
	  	Separability Clause	  	 	3	 
	 Section 1.06.
	  	Benefits of Supplemental Indenture	  	 	3	 
	 Section 1.07.
	  	Governing Law	  	 	3	 
	 Section 1.08.
	  	Execution in Counterparts	  	 	4	 
	 Section 1.09.
	  	Recitals by the Issuer and the Guarantor	  	 	4	 
	 Section 1.10.
	  	Ratification and Incorporation of Original Indenture	  	 	4	 
	ARTICLE 2	 
	DESIGNATED SECURITIES	 
	 Section 2.01.
	  	Creation of Designated Securities	  	 	4	 
	 Section 2.02.
	  	Limitation on Aggregate Principal Amount of Designated Securities	  	 	4	 
	 Section 2.03.
	  	Payment of Principal	  	 	4	 
	 Section 2.04.
	  	Interest and Interest Rate	  	 	4	 
	 Section 2.05.
	  	Paying Agent	  	 	5	 
	 Section 2.06.
	  	Place of Payment	  	 	7	 
	 Section 2.07.
	  	Denominations	  	 	7	 
	 Section 2.08.
	  	Listing	  	 	7	 
	 Section 2.09.
	  	Security Certificates	  	 	7	 
	 Section 2.10.
	  	Defeasance and Covenant Defeasance	  	 	8	 
	 Section 2.11.
	  	Additional Amounts	  	 	8	 
	 Section 2.12.
	  	Redemption	  	 	9	 
	 Section 2.13.
	  	Consolidation, Merger, Conveyance, Transfer or Lease; Assumption	  	 	10	 
	 Section 2.14.
	  	Procedures; Payment Statement	  	 	10	 
	 Section 2.15.
	  	Maintenance of Tax Procedures	  	 	10	 
	 Section 2.16.
	  	Certificated Securities	  	 	11	 
	 Section 2.17.
	  	USA Patriot Act	  	 	11	 
	 Section 2.18.
	  	Additional Rights	  	 	11	 
	 EXHIBIT A
	  	Form of Security Certificate Representing Designated Securities	  	 	A-1	 
	 EXHIBIT B
	  	Procedures to be Performed by the Issuer, the Guarantor and the Paying Agent in Connection with Spanish Law 10/2014, of June 26 and Royal Decree 1065/2007, of July 27	  	 	B-1	 

  
 i 

 THIS FIRST SUPPLEMENTAL INDENTURE, dated as of March 1, 2019, among Telefónica
Emisiones, S.A.U., a sociedad anónima unipersonal incorporated under the laws of the Kingdom of Spain (the “Issuer”), Telefónica, S.A., a sociedad anónima incorporated under the laws of the Kingdom
of Spain (the “Guarantor”), and The Bank of New York Mellon, a New York banking corporation, as trustee, transfer agent, registrar (the “Trustee”, which term includes any successor Trustee) and paying agent (the
“Paying Agent”, which term includes any successor Paying Agent). 
 WHEREAS, the Issuer has heretofore entered into an
Indenture, dated as of April 20, 2018 (as amended and supplemented, the “Original Indenture”), with the Guarantor and the Trustee; 

WHEREAS, the Original Indenture is incorporated herein by reference and the Original Indenture, as supplemented by this Supplemental Indenture
with respect to the Designated Securities (as this term is defined in Section 2.01 below), is herein called the “Indenture”; 

WHEREAS, the Issuer proposes to create a new series of Securities under the Indenture; 

WHEREAS, Mr. Carlos David Maroto Sobrado, as Joint and Several Director (Administrador Solidario) of the Issuer and in the context
of a general authorization approved by the Guarantor as sole shareholder of the Issuer on April 13, 2018 in favor of the Joint and Several Directors (Administradores Solidarios) of the Issuer, hereby resolves to issue the
Designated Securities in an aggregate principal amount of $1,250,000,000 and with the terms and conditions referred to in this Supplemental Indenture; and 

WHEREAS, all things necessary to make this Supplemental Indenture a valid agreement of the Issuer and the Guarantor, in accordance with its
terms, have been done; 
 NOW, THEREFORE, for and in consideration of the premises and the purchases of the Designated Securities by the
Holders thereof, it is mutually covenanted and agreed, for the equal and proportionate benefit of all Holders of Designated Securities, as follows: 

ARTICLE 1 
 DEFINITIONS AND OTHER
PROVISIONS OF GENERAL APPLICATION 
 Section 1.01.    Definitions. For all purposes of this Supplemental
Indenture, except as otherwise expressly provided or unless the context otherwise requires: 
 (a)    the terms defined
in this Article have the meanings assigned to them in this Article and include the plural as well as the singular; 

(b)     all other terms used herein which are defined in the Trust Indenture Act, either directly or by reference therein,
have the meanings assigned to them therein; 
 (c)    all accounting terms not otherwise defined herein have the
meanings assigned to them in accordance with generally accepted accounting principles, and, except as otherwise herein expressly provided, the term “generally accepted accounting principles”, or “GAAP”, with respect
to any computation required or permitted hereunder shall mean (i) in the case of the Issuer’s and the Guarantor’s unconsolidated financial statements, the accounting principles generally accepted in the Kingdom of Spain and
(ii) in the case of the Guarantor’s consolidated financial statements, International Financial Reporting Standards (“IFRS”) as adopted by the European Union, in each case as in effect at the date of such computation and as
applied by the Issuer or the Guarantor, as the case may be; 
 (d)    unless the context otherwise requires, any
reference to an “Article” or a “Section” means an Article or a Section, as the case may be, of this Supplemental Indenture; 

(e)    the words “herein”, “hereof” and “hereunder” and other words of
similar import refer to this Supplemental Indenture as a whole and not to any particular Article, Section or other subdivision; and 

  
 1 

 (f)    all terms used but not defined in this Supplemental Indenture,
which are defined in the Original Indenture, shall have the meanings assigned to them in the Original Indenture. 
 “Business
Day” means a day other than a Saturday, a Sunday or any other day on which banking institutions in New York, New York or the city of Madrid, Spain, are authorized or required by law or executive order to close. 

“Comparable Treasury Issue” means the United States Treasury security selected by an Independent Investment Banker as having
a maturity comparable to the remaining term of the Designated Securities to be redeemed (assuming for this purpose that the Designated Securities mature on the Par Call Date (as defined below)) that would be utilized, at the time of selection and in
accordance with customary financial practice, in pricing new issues of corporate debt securities of comparable maturity to the remaining term of the Designated Securities being redeemed. 

“Comparable Treasury Price” means, with respect to any Redemption Date prior to the Par Call Date, (1) the average of
the Reference Treasury Dealer Quotations for such Redemption Date, after excluding the highest and lowest such Reference Treasury Dealer Quotations, or (2) if the Independent Investment Banker obtains fewer than three such Reference Treasury
Dealer Quotations, the average of all such Quotations or, if only one such Quotation is obtained, such Quotation. 

“Depositary” means The Depository Trust Company and its successors. 

“Designated Guarantee” means that certain guarantee dated March 1, 2019, executed and delivered by the Guarantor and
endorsed on each Security Certificate representing Designated Securities, pursuant to which, among other things, the Guarantor shall unconditionally and irrevocably guarantee to the Holders of the Designated Securities the due and punctual payment
of principal of, premium, if any, and interest and all other amounts due under the Indenture and the Designated Securities. 

“Designated Securities” has the meaning ascribed in Section 2.01. 

“Fixed Rate Business Day” means a day other than a Saturday, a Sunday or any other day on which banking institutions in New
York, New York, London, England or the city of Madrid, Spain are authorized or required by law or executive order to close. 

“Guarantor” means the Person named as “Guarantor” in the first paragraph of this Supplemental Indenture. 

“Independent Investment Banker” means an independent investment banking institution of national standing appointed by the
Issuer and the Guarantor. 
 “Interest Payment Date” has the meaning ascribed in Section 2.04(b). 

“Issuer” means the Person named as “Issuer” in the first paragraph of this Supplemental Indenture. 

“New York Business Day” means a day other than a Saturday, a Sunday or any other day on which banking institutions in New
York, New York are authorized or required by law or executive order to close. 
 “Par Call Date” means September 1,
2048. 
 “Paying Agent” means the Person named as “Paying Agent” in the first paragraph of this Supplemental
Indenture. 
 “Payment Statement” means the statement to be delivered to the Issuer and the Guarantor by the Paying Agent,
substantially in the form set forth in Annex I to Exhibit B, pursuant to Section 2.14. 
 “Prospectus Supplement”
means the Final Prospectus Supplement dated February 26, 2019 and filed with the SEC on February 28, 2019 relating to the offering of the Designated Securities. 

“Redemption Date” has the meaning ascribed in Section 2.12. 

“Redemption Price” has the meaning ascribed in Section 2.12. 

  
 2 

 “Reference Treasury Dealer” means (1) each of Barclays Capital Inc.,
Goldman Sachs & Co. LLC and Merrill Lynch, Pierce, Fenner & Smith Incorporated and their affiliates or their respective successors, provided that if any of the foregoing shall cease to be a primary U.S. government securities
dealer in New York City (a “Primary Treasury Dealer”), the Issuer and the Guarantor will substitute therefor another Primary Treasury Dealer and (2) any other Primary Treasury Dealer selected by the Issuer and the Guarantor.

 “Reference Treasury Dealer Quotations” means, with respect to each Reference Treasury Dealer and any Redemption Date
prior to the Par Call Date, the average, as determined by the Independent Investment Banker, of the bid and asked prices for the Comparable Treasury Issue (expressed in each case as a percentage of its principal amount) quoted in writing to the
Independent Investment Banker by the Reference Treasury Dealer at 5:00 p.m. on the third New York Business Day preceding such Redemption Date. 

“Regular Record Date” means the tenth New York Business Day prior to the applicable Interest Payment Date. 

“Relevant Date” means, in respect of any payment, the date on which such payment first becomes due and payable, but if the
full amount of the moneys payable has not been received by the Paying Agent on or prior to such due date, it means the first date on which, the full amount of such moneys having been so received and made available for payment to Holders, notice to
that effect is duly given to the Holders in accordance with the Indenture. 
 “Stated Maturity” means March 1, 2049.

 “Supplemental Indenture” means this instrument as originally executed or as it may from time to time be supplemented or
amended in accordance with the terms of the Indenture. 
 “Treasury Rate” means, with respect to any Redemption Date prior
to the Par Call Date, the rate per annum equal to the semi-annual equivalent yield to maturity or, if such equivalent is not available, the interpolated maturity (on a day count basis) of the Comparable Treasury Issue, calculated assuming a price
for the Comparable Treasury Issue (expressed as a percentage of its principal amount) equal to the Comparable Treasury Price for such Redemption Date. The Treasury Rate shall be calculated by the Independent Investment Banker on the third New York
Business Day preceding the Redemption Date. 
 “Trustee” means the Person named as “Trustee” in the first
paragraph of this Supplemental Indenture. 
 Section 1.02. Conflict with Trust Indenture Act. If any provision hereof limits,
qualifies or conflicts with a provision of the Trust Indenture Act that is required under such Act to be a part of and govern the Indenture, the provision of the Trust Indenture Act shall control. If any provision of this Supplemental Indenture
modifies or excludes any provision of the Trust Indenture Act that may be so modified or excluded, the provision of the Trust Indenture Act shall be deemed to apply to this Supplemental Indenture as so modified or to be excluded, as the case may be.

 Section 1.03. Effect of Headings and Table of Contents. The Article and Section headings herein and the Table of Contents are
for convenience only and shall not affect the construction hereof. 
 Section 1.04. Successors and Assigns. All covenants and
agreements in this Supplemental Indenture by the Issuer or the Guarantor shall bind their respective successors and assigns, whether so expressed or not. 

Section 1.05. Separability Clause. In case any provision in this Supplemental Indenture, the Designated Securities or the
Designated Guarantee shall be invalid, illegal or unenforceable, the validity, legality and enforceability of the remaining provisions shall not in any way be affected or impaired thereby. 

Section 1.06. Benefits of Supplemental Indenture. Nothing in this Supplemental Indenture, the Indenture, the Designated Securities
or the Designated Guarantee, express or implied, shall give to any Person, other than the parties hereto and their successors hereunder and the Holders of Designated Securities, any benefit or any legal or equitable right, remedy or claim under the
Indenture. 
 Section 1.07. Governing Law. Pursuant to Section 5-1401 of the
General Obligations Law of the State of New York, this Supplemental Indenture, the Designated Securities and the Designated Guarantee shall be governed by, and construed in accordance with, the laws of the State of New York. 

  
 3 

 Section 1.08. Execution in Counterparts. This Supplemental Indenture may be
executed in any number of counterparts, each of which so executed shall be deemed to be an original, but all such counterparts shall together constitute but one and the same instrument. 

Section 1.09. Recitals by the Issuer and the Guarantor. The recitals in this Supplemental Indenture are made by the Issuer and the
Guarantor only and not by the Trustee, and all of the provisions contained in the Original Indenture in respect of the rights, privileges, immunities, powers and duties of the Trustee shall be applicable in respect of the Designated Securities, the
Designated Guarantee and of this Supplemental Indenture as fully and with like effect as if set forth herein in full. 

Section 1.10. Ratification and Incorporation of Original Indenture. As supplemented hereby, the Original Indenture is in all
respects ratified and confirmed, and the Original Indenture and this Supplemental Indenture shall be read, taken and construed as one and the same instrument. 

ARTICLE 2 
 DESIGNATED SECURITIES

 Section 2.01.    Creation of Designated Securities. There is hereby created a new series of Securities to
be issued under the Indenture, to be designated as Fixed Rate Senior Notes due 2049 (the “Designated Securities”). The Designated Securities have been designated as series “V” of the Issuer in the public deed of issuance
executed by one of the Joint and Several Directors (Administradores Solidarios) of the Issuer on February 27, 2019. 

Section 2.02.    Limitation on Aggregate Principal Amount of Designated Securities. The aggregate principal
amount of the Designated Securities shall initially be limited to $1,250,000,000 (except for Designated Securities represented by any Security Certificate authenticated and delivered upon registration of transfer of, or in exchange for, or in lieu
of, other Designated Securities pursuant to Section 2.4, 2.5, 2.7, 9.6 or 11.7 of the Original Indenture and except for any Designated Securities which, pursuant to Section 2.3 of the Original Indenture, are deemed never to have been
authenticated and delivered under the Indenture). The Issuer may from time to time, without the consent of the Holders of Designated Securities, create and issue further securities having the same terms and conditions as the previously issued
Designated Securities in all respects (or in all respects except for the issue date, the first Interest Payment Date (as defined herein) and/or the issue price), so that such further issue shall be consolidated and form a single series with the
Outstanding Designated Securities; provided, however, that any such further issuance will only be made if either such additional securities are issued with no more than de minimis original issue discount for U.S. federal income
tax purposes or any such further issuance is a “qualified reopening” as such term is defined under U.S. Treasury Regulations Section 1.1275-2(k)(3) promulgated under the U.S. Internal Revenue
Code of 1986, as amended. 
 Section 2.03.    Payment of Principal. The principal of the Outstanding
Designated Securities shall be due and payable at the Stated Maturity. 
 Section 2.04.    Interest and Interest
Rate.  
 (a)    The Designated Securities will bear interest from March 1, 2019 or from the most recent date
through which the Issuer has paid or provided for interest on the Designated Securities at an annual rate of 5.520%. 

(b)    The Issuer or the Guarantor, as the case may be, will pay interest on the Designated Securities semi-annually on
March 1 and September 1 of each year, beginning on September 1, 2019 until the Stated Maturity, and on the Stated Maturity (each an “Interest Payment Date”). 

(c)    Interest on the Designated Securities will be computed on the basis of a
360-day year of twelve 30-day months. Except as described below for the first Interest Payment Date, on each Interest Payment Date, the Issuer or the Guarantor, as the
case may be, will pay interest on the Designated Securities for the period commencing on and including the immediately preceding Interest Payment Date and ending on and including the day immediately preceding that Interest Payment Date. 

  
 4 

 (d)    On the first Interest Payment Date, the Issuer or the Guarantor,
as the case may be, will pay interest for the period beginning on and including the issue date of the Designated Securities and ending on and including August 31, 2019. 

(e)    If any Interest Payment Date falls on a day that is not a Fixed Rate Business Day, the interest payment shall be
postponed to the next day that is a Fixed Rate Business Day, and no interest on such payment shall accrue for the period from and after such Interest Payment Date. 

(f)    If the Stated Maturity of any Designated Security is not a Fixed Rate Business Day, payment of principal and
interest on the applicable Designated Security will be made on the next succeeding day that is a Fixed Rate Business Day, and no interest will accrue for the period from and after such Stated Maturity. 

(g)    Interest on each Designated Security will be paid only to the Person in whose name such Designated Security was
registered at the close of business on the Regular Record Date for the applicable Interest Payment Date. 

Section 2.05.    Paying Agent.  

(a)    Upon the terms and subject to the conditions contained herein, the Issuer hereby appoints The Bank of New York
Mellon as the initial Paying Agent under the Indenture for the purpose of performing the functions of the Paying Agent with respect to the Designated Securities. 

(b)    The Paying Agent shall exercise due care in performing the functions of the Paying Agent for the Designated
Securities. 
 (c)    The Paying Agent accepts its obligations set forth herein, upon the terms and subject to the
conditions hereof, including the following, to all of which the Issuer and the Guarantor agree: 

(i)    The Paying Agent shall be entitled to such compensation as may be agreed in writing with the Issuer
and the Guarantor for all services rendered by the Paying Agent, and the Issuer and the Guarantor promise to pay such compensation and to reimburse the Paying Agent for the reasonable
out-of-pocket expenses (including reasonable counsel fees and expenses) incurred by it in connection with the services rendered by it hereunder upon receipt of such
invoices as the Issuer and the Guarantor shall reasonably require. The Issuer and the Guarantor agree to indemnify the Paying Agent for, and to hold it harmless against, any and all loss, liability, damage, claims or expenses (including the costs
and expenses of defending against any claim of liability) incurred by the Paying Agent that arises out of or in connection with its acting as Paying Agent hereunder, except such as may result from the negligence, willful misconduct or bad faith of
the Paying Agent or any of its agents or employees. The Paying Agent shall incur no liability and shall be indemnified and held harmless by the Issuer and the Guarantor for, or in respect of, any actions taken, omitted to be taken or suffered to be
taken in good faith by the Paying Agent in reliance upon (A) the written opinion of counsel satisfactory to it and upon obtaining the prior written consent of the Issuer or the Guarantor or (B) written instructions from the Issuer and the
Guarantor. The provisions of this paragraph shall survive the termination of this Supplemental Indenture. 

(ii)    In acting under the Indenture and in connection with the Designated Securities, the Paying Agent is
acting solely as agent of the Issuer and the Guarantor and does not assume any obligations to, or relationship of agency or trust for or with, any of the Holders of the Designated Securities. 

(iii)    The Paying Agent shall be protected and shall incur no liability for or in respect of any action
taken or omitted to be taken or anything suffered by it in reliance upon the terms of the Designated Securities, any notice, direction, certificate, affidavit, statement or other paper, document or communication reasonably believed by it to be
genuine and to have been approved or signed by the proper party or parties. 

  
 5 

 (iv)    The Paying Agent shall be obligated to perform
only such duties as are herein specifically set forth and any duties necessarily incidental thereto, and no implied duties or obligations shall be read into the Indenture against the Paying Agent. 

(v)    Unless herein otherwise specifically provided, any order, certificate, notice, request, direction or
other communication from the Issuer or the Guarantor made or given by it under any provision of the Indenture shall be sufficient if signed by any proper officer or an authorized person of the Issuer or the Guarantor, as the case may be. 

(vi)    The Paying Agent may perform any duties hereunder either directly or by or through agents or
attorneys, and the Paying Agent shall not be responsible for any misconduct or negligence on the part of any agent or attorney appointed with due care by it hereunder. 

(d)    (i) The Paying Agent may at any time resign as Paying Agent by giving written notice to the Issuer and the
Guarantor of such intention on its part, specifying the date on which its desired resignation shall become effective; provided, however, that such date shall not be earlier than 60 days after the receipt of such notice by the Issuer
and the Guarantor, unless the Issuer and the Guarantor agree in writing to accept less notice. The Paying Agent may be removed (with or without cause) at any time by the filing with it of any instrument in writing signed on behalf of the Issuer and
the Guarantor by any proper officer or an authorized person thereof and specifying such removal and the date when it is intended to become effective, subject to (if such Paying Agent is not the Trustee) the written consent of the Trustee, which
consent shall not be unreasonably withheld. Such resignation or removal shall take effect only upon the date of the appointment by the Issuer and the Guarantor, as hereinafter provided, of a successor Paying Agent. If within 60 days after notice of
resignation or removal has been given, a successor Paying Agent has not been appointed, the Paying Agent may petition a court of competent jurisdiction to appoint a successor Paying Agent. A successor Paying Agent shall be appointed by the Issuer
and the Guarantor by an instrument in writing signed on behalf of the Issuer and the Guarantor, as the case may be, by any proper officer or an authorized person thereof and the successor Paying Agent. Upon the appointment of a successor Paying
Agent and acceptance by it of such appointment, the Paying Agent so superseded shall cease to be such Paying Agent hereunder. Upon its resignation or removal, the Paying Agent shall be entitled to the payment by the Issuer and the Guarantor of its
compensation, if any is owed to it, for services rendered hereunder and to the reimbursement of all reasonable out-of-pocket expenses incurred in connection with the
services rendered by it hereunder. 
 (ii)    Any successor Paying Agent appointed hereunder shall
execute and deliver to its predecessor and to the Issuer and the Guarantor an instrument accepting such appointment hereunder, and thereupon such successor Paying Agent, without any further act, deed or conveyance, shall become vested with all the
authority, rights, powers, trusts, immunities, duties and obligations of such predecessor with like effect as if originally named as such Paying Agent hereunder, and such predecessor, upon payment of its charges and disbursements then unpaid, shall
thereupon become obliged to transfer and deliver, and such successor Paying Agent shall be entitled to receive, copies of any relevant records maintained by such predecessor Paying Agent. 

(iii)    Any Person into which the Paying Agent may be merged or converted or with which the Paying Agent
may be consolidated, or any Person resulting from any merger, conversion or consolidation to which the Paying Agent shall be a party, or any Person succeeding to all or substantially all of the assets and business of the Paying Agent, or all or
substantially all of the corporate trust business of the Paying Agent shall, to the extent permitted by applicable law and provided that it shall have an established place of business in The City of New York, be the successor Paying Agent under the
Indenture without the execution or filing of any paper or any further act on the part of any of the parties hereto. Notice of any such merger, conversion, consolidation or sale shall forthwith be given to the Issuer and the Guarantor within 30 days
of such merger, conversion, consolidation or sale. 
 (iv)    Any notice, communication or other document
(other than a notice, communication or other document delivered pursuant to the procedures set forth in Exhibit B, including a Payment Statement) 

  
 6 

 
required to be given by the Paying Agent to any person hereunder shall be given in accordance with Section 1.5 of the Original Indenture. Any notice, communication or other document (other
than a notice, communication or other document delivered pursuant to the procedures set forth in Exhibit B, including a Payment Statement) to be given to the initial Paying Agent shall be delivered in person, sent by letter or communicated by
telephone (subject, in the case of communications by telephone, to confirmation dispatched within twenty-four hours by letter), to the following address (or to any other address of which the Paying Agent shall have notified the others in writing):
The Bank of New York Mellon, 240 Greenwich Street, New York, New York 10007, Attention: International Corporate Trust. Any notice, communication or other document hereunder given or delivered by telephone or letter shall be deemed to be received
when in the ordinary course of transmission or post, as the case may be, it would be received. 

Section 2.06.    Place of Payment. (a) The place or places where, subject to the provisions of
Section 10.2 of the Original Indenture, the principal of, and any premium and interest on, and any Additional Amounts in respect of, the Designated Securities shall be payable, Security Certificates representing the Designated Securities may be
surrendered for exchange or conversion of the Designated Securities represented thereby and notices and demands to or upon the Issuer or the Guarantor in respect of the Designated Securities and the Indenture may be served shall be the Corporate
Trust Office of the Trustee. 
 (b)    Upon the deposit with the Paying Agent of a sum sufficient to pay the principal
of, or any premium or interest on, or any Additional Amounts in respect of, as the case may be, the Designated Securities on or prior to the Relevant Date, the Issuer or the Guarantor, as the case may be, will have fully complied with its payment
obligations under Section 10.3(b) of the Original Indenture with respect to any such amount. 

Section 2.07.    Denominations. The Designated Securities may be issued in denominations of $1,000 and
integral multiples thereof. 
 Section 2.08.    Listing. From and including the issue date of the Designated
Securities to and including the first Interest Payment Date in respect of the Designated Securities, the Issuer will use its reasonable best efforts to obtain or maintain, as applicable, a listing of the Designated Securities on the New York Stock
Exchange or another regulated market, multilateral trading facility or other organized market. 

Section 2.09.    Security Certificates.  

(a)    The Designated Securities shall initially be represented by one or more Global Certificates substantially in the
form of Exhibit A, which shall be deposited with a custodian for the Depositary and the Designated Securities represented thereby will be registered in the name of a nominee of the Depositary, for the accounts of participants in the Depositary. 

(b)    Designated Securities represented by a Global Certificate may be transferred, in whole and not in part, only:
(i) by the Depositary to a nominee of the Depositary, (ii) by a nominee of the Depositary to the Depositary or to another nominee of the Depositary, or (iii) by the Depositary or any such nominee to a successor Depositary or a nominee
of such successor Depositary. 
 (c)    Beneficial interests in any Designated Securities represented by a Global
Certificate will be exchangeable for Designated Securities represented by Definitive Certificates only if: (i) the Depositary notifies the Issuer that it is unwilling or unable to continue to act as Depositary or that it is no longer a clearing
agency registered under the Exchange Act and, in either case, a successor Depositary is not appointed by the Issuer within 120 days after the date of such notice from the Depositary, (ii) the Issuer notifies the Trustee in writing that it has
reasonably elected to cause the issuance of Designated Securities represented by Definitive Certificates or (iii) there shall have occurred and be continuing an Event of Default with respect to the Designated Securities and the Designated
Securities will be accelerated in accordance with their terms and the terms of the Indenture. 
 (d)    Upon the
occurrence of any of the events specified in (i), (ii) or (iii) of (c) above, Designated Securities represented by Definitive Certificates shall be (i) delivered by the Trustee in exchange for beneficial interest in Designated
Securities represented by Global Certificates and (ii) registered in such names, and issued in such authorized denominations, as shall be requested by or on behalf of the Depositary in accordance with its customary procedures. 

  
 7 

 Section 2.10.    Defeasance and Covenant Defeasance. The
provisions of Sections 4.3 and 10.8 of the Original Indenture will apply to the Designated Securities, except that: 

(i)    Section 4.3(c) of the Original Indenture shall be deleted with respect to the Designated Securities
only and shall not apply to the Designated Securities and shall, with respect to the Designated Securities only, be replaced by the following provision: 

“the Issuer or the Guarantor has delivered to the Trustee an Opinion of Counsel of recognized standing with respect to U.S. federal income
tax matters (which opinion must state that it is based on a change in law or a ruling received from the Internal Revenue Service) to the effect that Beneficial Owners of the Securities of that series will not recognize income, gain or loss for
United States federal income tax purposes as a result of such deposit, Defeasance and discharge and will be subject to United States federal income tax on the same amount and in the same manner and at the same times, as would have been the case if
such deposit, Defeasance and discharge had not occurred; and”; 
 (ii)    Section 10.8(a)(iv) of the
Original Indenture shall be deleted with respect to the Designated Securities only and shall not apply to the Designated Securities and shall, with respect to the Designated Securities only, be replaced by the following provision: 

“the Issuer or the Guarantor has delivered to the Trustee an Opinion of Counsel of recognized standing with respect to U.S. federal income
tax matters to the effect that the Beneficial Owners of the Securities of that series will not recognize income, gain or loss for United States federal income tax purposes as a result of such deposit and Covenant Defeasance and will be subject to
United States federal income tax on the same amount and in the same manner and at the same times, as would have been the case if such deposit and Covenant Defeasance had not occurred; and”. 

Section 2.11.    Additional Amounts.  

(a)    Except as otherwise provided in this Section 2.11, the provisions of Section 10.4 of the Original
Indenture will apply to the Designated Securities; provided, however, that the Issuer and the Guarantor will not be required to pay any Additional Amounts in respect of any Designated Security: 

(i)    in respect of which the Holder (or the Beneficial Owner for whose benefit it holds such Designated
Security) is liable for such taxes, duties, assessments or governmental charges by reason of it (or the Beneficial Owner for whose benefit it holds such Designated Security) having some connection with the Kingdom of Spain other than (a) the
mere holding of such Designated Security (or such beneficial interest) or (b) the receipt of principal, redemption amount, interest or other amount in respect of such Designated Security; 

(ii)    in respect of which the Issuer or the Guarantor have not received such documentation or information
as may be necessary to allow payments on such Designated Security to be made free and clear of Spanish withholding tax or deduction on account of Spanish taxes, including a duly executed and completed Payment Statement from the Paying Agent,
pursuant to Law 10/2014 of June 26 and Royal Decree 1065/2007 of July 27, each as amended, and any implementing legislation or regulation, or pursuant to any other law or regulation substituting or amending such law or regulation; 

(iii)    in relation to any estate, inheritance, gift, sales, transfer or similar taxes; 

  
 8 

 (iv)    presented for payment (where presentation is
required) more than 30 days after the Relevant Date, except to the extent that the relevant Holder would have been entitled to such Additional Amounts on presenting the same for payment on the expiry of such period of 30 days; 

(v)    presented for payment (where presentation is required) by or on behalf of a Holder (or Beneficial
Owner) who would have been able to avoid such withholding or deduction by presenting the relevant Designated Security to another paying agent; 

(vi)    in the event that the Designated Securities are redeemed pursuant to Section 2.12(b) hereof;
or 
 (vii)    in respect of any withholding or deduction that is imposed pursuant to Sections 1471
through 1474 of the U.S. Internal Revenue Code of 1986 and the U.S. Treasury regulations thereunder (“FATCA”), any intergovernmental agreement between the United States and any other jurisdiction implementing or relating to FATCA,
any law, regulation, guidance or interpretations enacted or issued in any jurisdiction with respect thereto, or any agreements entered into in connection with the implementation thereof; 

provided further that Additional Amounts in respect of the Designated Securities will also not be paid with respect to
any payment to a Holder of any Designated Securities who is a fiduciary, a partnership, a limited liability company or anything other than the sole Beneficial Owner of that payment, to the extent to which that payment would be required by the laws
of the Kingdom of Spain (or any political subdivision thereof or any authority or agency therein or thereof having power to tax) to be included in the income, for tax purposes, of a beneficiary or settlor with respect to the fiduciary, a member of
that partnership, an interest holder in that limited liability company or a Beneficial Owner who would not have been entitled to any Additional Amounts had it been the Holder. 

(b)    In the event of an early redemption of the Designated Securities pursuant to Section 2.12(b) of this
Supplemental Indenture, the Issuer or the Guarantor, as the case may be, will be required to withhold tax and will pay interest in respect of the principal amount of the Designated Securities redeemed net of the Spanish withholding tax applicable to
such payments. If this were to occur, Beneficial Owners will have to follow the Direct Refund from Spanish Tax Authorities Procedures set forth in Annex A to the Prospectus Supplement in order to apply directly to the Spanish tax authorities for any
refund to which they may be entitled. 
 Section 2.12.    Redemption. (a) The provisions of Article 11
of the Original Indenture will apply to the Designated Securities, except that the notice of redemption of Designated Securities to be redeemed at the option of the Issuer pursuant to Section 11.2 of the Original Indenture, shall be given not
less than 15 nor more than 60 days prior to the Redemption Date to each Holder of the Designated Securities to be redeemed (rather than in accordance with the period set forth in Section 11.4 of the Original Indenture) and otherwise in
accordance with Section 11.4 of the Original Indenture. The “Redemption Price” means: (A) with respect to any Designated Securities to be redeemed pursuant to Section 11.2 of the Original Indenture prior to the Par
Call Date, an amount equal to the greater of: (x) 100% of the principal amount of such Designated Securities to be redeemed plus accrued and unpaid interest thereon to, but excluding, the Redemption Date (as defined below) of such Designated
Securities and (y) as determined by the Independent Investment Banker, the sum of the present values of the remaining scheduled payments of principal and interest on the Designated Securities being redeemed that would be due if such Designated
Securities matured on the Par Call Date (exclusive of accrued and unpaid interest thereon to, but excluding, the Redemption Date) discounted to the Redemption Date of the Designated Securities being redeemed on a semiannual basis (assuming a 360-day year consisting of twelve 30-day months) at the Treasury Rate plus 40 basis points for the Designated Securities being redeemed, plus accrued and unpaid interest on
the principal amount of such Designated Securities (or any portion thereof) being redeemed to, but excluding, the Redemption Date of the Designated Securities (or any portion thereof) being redeemed; and (B) with respect to any Designated
Securities to be redeemed pursuant to Section 11.2 of the Original Indenture on or after the Par Call Date, Section 11.8 of the Original Indenture or Section 2.12(b) of this Supplemental Indenture, an amount equal to their principal
amount, together with accrued and unpaid interest, if any, thereon to, but excluding, the Redemption Date. The “Redemption Date” of any Designated Securities to be redeemed will be any Fixed Rate Business Day fixed by the Issuer for
redemption of such Designated Securities and specified in the applicable notice of redemption provided by the 

  
 9 

 
Issuer to the Trustee pursuant to Section 11.2 of the Original Indenture; provided, however, that the Redemption Date of any Designated Securities to be redeemed pursuant to
Section 11.8(a) of the Original Indenture shall be an Interest Payment Date. 
 (b)    In addition, if the
Designated Securities are not listed on a regulated market, multilateral trading facility or other organized market no later than 45 days prior to the first Interest Payment Date, the Issuer or the Guarantor, as the case may be, may, at its
respective option and having given no less than 15 days’ notice (ending on a day which is no later than the Business Day immediately preceding such first Interest Payment Date) to the Holders of the Designated Securities and upon proper notice
as provided in the Indenture (which notice shall be irrevocable) redeem all of the Outstanding Designated Securities at the applicable Redemption Price specified in Section 2.12(a)(B) of this Supplemental Indenture; provided that from
and including the issue date of the Designated Securities to and including such Interest Payment Date, the Issuer will use its reasonable best efforts to obtain or maintain such listing, as applicable. 

Section 2.13.    Consolidation, Merger, Conveyance, Transfer or Lease; Assumption. The provisions of Article
8 of the Original Indenture will apply to the Designated Securities, except that Section 8.1(b) of the Original Indenture shall be deleted with respect to the Designated Securities only and shall not apply to the Designated
Securities and shall, with respect to the Designated Securities only, be replaced by the following provision: 
 “if the Person formed
by such consolidation or into which the Issuer or the Guarantor is merged or to whom the Issuer or the Guarantor has conveyed, transferred or leased its properties or assets is a Person organized and validly existing under the laws of a jurisdiction
other than the Kingdom of Spain such Person agrees to indemnify the Holder of each Security of each series against any costs or expenses of the act of such consolidation, merger, conveyance, transfer or lease;”. 

Section 2.14.    Procedures; Payment Statement. The Issuer, the Guarantor and the Paying Agent shall, in
connection with any Interest Payment Date or Redemption Date (other than a Redemption Date in respect of an early redemption of the Designated Securities pursuant to Section 2.12(b) of this Supplemental Indenture), comply with the procedures
set forth in Exhibit B, including the timely provision by the Paying Agent of a duly executed and completed Payment Statement to the Issuer and the Guarantor. Compliance with the procedures set forth in Exhibit B, including the timely provision by
the Paying Agent of a duly executed and completed Payment Statement to the Issuer and the Guarantor, shall not be required in connection with an early redemption of the Designated Securities pursuant to Section 2.12(b) of this Supplemental
Indenture. If the timely provision of a duly executed and completed Payment Statement is no longer necessary under Spanish law to allow payments on the Designated Securities to be made free and clear of Spanish withholding tax or deduction on
account of Spanish taxes, this Section 2.14 of this Supplemental Indenture shall cease to be in effect and the Issuer, the Guarantor and the Paying Agent shall no longer be required to comply with the procedures set forth in Exhibit B,
including the timely provision by the Paying Agent of a duly executed and completed Payment Statement to the Issuer and the Guarantor with respect to any Interest Payment Date or Redemption Date occurring on or after the date on which the timely
provision of such Payment Statement is no longer necessary under Spanish law to allow payments on the Designated Securities to be made free and clear of Spanish withholding tax or deduction on account of Spanish taxes. Notwithstanding anything
contained herein to the contrary, the Paying Agent shall not be liable for any amounts owed to any person due to its failure to properly comply with the tax procedures referred to in Section 2.14 and Section 2.15 of this Supplemental
Indenture, except such as may result from the negligence, willful misconduct or bad faith of the Paying Agent or any of its agents or employees. 

Section 2.15.    Maintenance of Tax Procedures. So long as any principal amount of the Designated Securities
remains outstanding, the Issuer and the Guarantor shall, insofar as it is practicable, maintain, implement or arrange for the implementation of procedures to facilitate the timely provision by the Paying Agent of a duly executed and completed
Payment Statement in respect of the payments referred to in Section 2.14 of this Supplemental Indenture under the Designated Securities or the collection of any other documentation concerning the Designated Securities that may be required under
Spanish law to allow payments on the Designated Securities to be made free and clear of Spanish withholding tax. 

  
 10 

 Section 2.16.    Certificated Securities. Any Certificated
Securities issued in exchange for Beneficial Interests in the Designated Securities represented by Global Certificates pursuant to Section 2.5 of the Original Indenture shall be issued in the State of New York. 

Section 2.17.    USA Patriot Act. The parties hereto acknowledge that, in accordance with Section 326 of
the USA Patriot Act (Title III of Pub. L. 107-56 (signed into law October 26, 2001)) (as amended, modified or supplemented from time to time, the “USA Patriot Act”), the Trustee, like all
financial institutions, is required to obtain, verify, and record information that identifies each person or legal entity that opens an account. The parties to this Supplemental Indenture agree that they will provide the Trustee with such
information regarding the identification of the Issuer and the Guarantor as the Trustee may request in order for the Trustee to satisfy the requirements of the USA Patriot Act. 

Section 2.18.    Additional Rights. In addition to their rights under the Original Indenture, the parties
hereto shall be provided with the following additional rights: 
 (a)    The permissive rights of the Trustee enumerated
herein shall not be construed as duties. 
 (b)     The parties hereto shall not be responsible or liable to one
another for any failure or delay in the performance of its obligations under the Indenture arising out of or caused, directly or indirectly, by circumstances beyond its reasonable control, including without limitation, acts of God; earthquakes;
fires; floods; wars; civil or military disturbances; sabotage; epidemics; riots; interruptions, loss or malfunctions of utilities, computer (hardware or software) or communications service; accidents; labor disputes; acts of civil or military
authority or governmental actions; it being understood that the parties hereto shall use their best efforts to resume performance as soon as practicable under the circumstances. 

(c)    Under no circumstances will any party to this Supplemental Indenture be liable to any other party to this
Supplemental Indenture for any special, indirect, punitive or consequential loss or damage (including, but not limited to, the loss of business, goodwill, opportunity or profit) whether or not foreseeable and even if advised of the possibility of
such loss or damage and regardless of whether the claim for loss or damage is made in negligence, for breach of contract, breach of trust, breach of fiduciary obligation or otherwise. 

  
 11 

 IN WITNESS WHEREOF, each of the parties hereto has caused this First
Supplemental Indenture to be duly executed on its behalf as of the date first above written. 
  

			
	 TELEFÓNICA EMISIONES, S.A.U.,

as Issuer

		
	By:	 	 /s/ Carlos David Maroto

	Name:	 	Carlos David Maroto
	Title:	 	Joint and Several Director

  

			
	 TELEFÓNICA, S.A.,
 as
Guarantor

		
	By:	 	 /s/ Jesús Romero Albarracín

	Name:	 	Jesús Romero Albarracín
	Title:	 	Authorised Officer

  

			
	 THE BANK OF NEW YORK MELLON,
 as
Trustee, Transfer Agent, Registrar and Paying Agent

		
	By:	 	 /s/ Laurence J. O’Brien

	Name:	 	Laurence J. O’Brien
	Title:	 	Vice President

 FIRST SUPPLEMENTAL INDENTURE 

 EXHIBIT A 

FORM OF SECURITY CERTIFICATE REPRESENTING DESIGNATED SECURITIES 

TELEFÓNICA EMISIONES, S.A.U. 

Fixed Rate Senior Notes due 2049 

Guaranteed by 

TELEFÓNICA, S.A. 
  

			
	No.         	  	CUSIP No. 87938W AX1
		  	ISIN No. US87938W AX11

 UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR DEFINITIVE CERTIFICATES, THIS GLOBAL CERTIFICATE MAY
BE TRANSFERRED, IN WHOLE AND NOT IN PART, ONLY: (I) BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY, (II) BY A NOMINEE OF THE DEPOSITARY TO THE DEPOSITARY OR TO ANOTHER NOMINEE OF THE DEPOSITARY, OR (III) BY THE DEPOSITARY OR ANY
SUCH NOMINEE TO A SUCCESSOR DEPOSITARY OR A NOMINEE OF SUCH SUCCESSOR DEPOSITARY, AND TRANSFERS OF THE SECURITIES REPRESENTED BY THIS GLOBAL CERTIFICATE AND ANY BENEFICIAL INTERESTS IN ANY SECURITIES REPRESENTED BY THIS GLOBAL CERTIFICATE SHALL BE
LIMITED TO TRANSFERS MADE IN ACCORDANCE WITH THE RESTRICTIONS SET FORTH IN THE INDENTURE REFERRED TO BELOW. 
 UNLESS THIS CERTIFICATE IS
PRESENTED BY AN AUTHORIZED REPRESENTATIVE OF THE DEPOSITORY TRUST COMPANY, A NEW YORK CORPORATION (“DTC”), TO THE ISSUER OR ITS AGENT FOR REGISTRATION OF TRANSFER, EXCHANGE OR PAYMENT, AND ANY CERTIFICATE ISSUED IS REGISTERED BY AN
AUTHORIZED REPRESENTATIVE OF DTC (AND ANY PAYMENT IS MADE TO CEDE & CO. OR TO SUCH OTHER ENTITY AS IS REQUESTED BY AN AUTHORIZED REPRESENTATIVE OF DTC), ANY TRANSFER, PLEDGE OR OTHER USE HEREOF FOR VALUE OR OTHERWISE BY OR TO ANY PERSON IS
WRONGFUL INASMUCH AS THE REGISTERED OWNER HEREOF, CEDE & CO., HAS AN INTEREST HEREIN. 
 TELEFÓNICA EMISIONES, S.A.U., a
sociedad anónima unipersonal incorporated under the laws of the Kingdom of Spain (herein called the “Issuer”, which term includes any successor Person under the Indenture referred to hereinafter), for value received,
hereby promises to pay to Cede & Co., or registered assigns, the principal sum of $                , as revised by the Schedule of Increases or Decreases
attached hereto, on March 1, 2049, and to pay interest thereon from March 1, 2019, or from the most recent Interest Payment Date to which interest has been paid or duly provided for, in arrears on March 1 and September 1 of each
year, beginning on September 1, 2019 at the rate of 5.520% per annum until the Stated Maturity, and on the Stated Maturity. 
 The
Designated Securities are issuable in denominations of $1,000 and integral multiples thereof. 
 Interest will be computed on the basis of a
360-day year of twelve 30-day months. Except as provided below for the first Interest Payment Date, on each Interest Payment Date, the Issuer or the Guarantor (as
defined herein), as the case may be, will pay interest on the Designated Securities (as defined herein) for the period commencing on and including the immediately preceding Interest Payment Date and ending on and including the day immediately
preceding that Interest Payment Date. On the first Interest Payment Date, the Issuer or the Guarantor (as defined herein), as the case may be, will pay interest for the period beginning on and including the issue date and ending on and including
August 31, 2019. If any Interest Payment Date falls on a day that is not a Fixed Rate Business Day, the interest payment shall be postponed to the next day that is a Fixed Rate Business Day and no interest on such payment shall accrue for the
period from and after such Interest Payment Date. If the Stated Maturity of the Designated Securities is not a Fixed Rate Business Day, payment of principal and interest on the Designated Securities will be made on the next succeeding day that is a
Fixed Rate Business Day and no interest will accrue for the period from and after the Stated Maturity. 

  
 A-1 

 The interest so payable, and punctually paid or duly provided for, on any Interest Payment
Date will, as provided in the Indenture, be paid to the Person in whose name the Designated Securities represented hereby (or one or more Predecessor Securities) are registered at the close of business on the Regular Record Date for such Interest
Payment Date, which shall be the tenth New York Business Day prior to the applicable Interest Payment Date. Any such interest not so punctually paid or duly provided for will forthwith cease to be payable to the Holder on such Regular Record Date
and may either be paid to the Person in whose name the Designated Securities represented hereby (or one or more Predecessor Securities) are registered at the close of business on a Special Record Date for the payment of such Defaulted Interest to be
fixed by the Trustee, notice whereof shall be given to Holders of Designated Securities not less than 10 days prior to such Special Record Date, or be paid at any time in any other lawful manner not inconsistent with the requirements of any
securities exchange on which the Designated Securities may be listed, and upon such notice as may be required by such exchange, all as more fully provided in the Indenture. 

For informational purposes only, without any substantive effect whatsoever and solely in order to comply with Article 413, letter (d) of
the Spanish Law on Corporations (Ley de Sociedades de Capital), approved by Royal Decree (Real Decreto Legislativo) 1/2010, of July 2, it is hereby noted that the aggregate principal amount of the Designated Securities was
equivalent to €1,102,098,395.30 based on the Noon Buying Rate as determined and published by the Federal Reserve, as of February 22, 2019, for the Euro of $1.1342 per €1.00. Amounts due under the Designated Securities shall not under
any circumstances whatsoever be payable in any currency other than U.S. dollars or such coin or currency of the United States as at the time of payment shall be legal tender for the payment of public and private debts. 

The Bank of New York Mellon shall initially act as Trustee, Transfer Agent, Registrar and Paying Agent with respect to the Designated
Securities. 
 Reference is hereby made to the further provisions of the Designated Securities set forth on the reverse of this Security
Certificate, which further provisions shall for all purposes have the same effect as if set forth at this place. 
 Unless the certificate
of authentication hereon has been executed by the Trustee referred to on the reverse hereof, directly or through an Authenticating Agent, by manual signature of an authorized signatory, the Designated Securities represented by this Security
Certificate shall not be entitled to any benefit under the Indenture or be valid or obligatory for any purpose. 
 The public deed of
issuance (escritura de emisión) related to the Designated Securities represented hereby was granted on February 27, 2019 before Mr. José Miguel García Lombardía, Notary of Madrid with the number 911 of
his files. 

  
 A-2 

 IN WITNESS WHEREOF, the Issuer has caused this instrument to be duly executed manually or in
facsimile. 
  

							
	Dated: March 1, 2019	 		 	TELEFÓNICA EMISIONES, S.A.U.
				
		 		 	By:	 	
                

		 		 	Name:	 	
		 		 	Title:	 	

  
 A-3 

 CERTIFICATE OF AUTHENTICATION 

This is one of the Security Certificates representing the Securities of the series designated thereon referred to in the within-mentioned
Indenture. 
  

							
	Dated: March 1, 2019	 		 	 THE BANK OF NEW YORK MELLON
 as
Trustee

				
		 		 	Manually By:	 	             

		 		 	Name:	 	
		 		 	Title:	 	

  
 A-4 

 GUARANTEE 

For value received, Telefónica, S.A., a sociedad anónima organized under the laws of the Kingdom of Spain, having its
registered office at Gran Vía, 28, 28013 Madrid, Spain (herein called the “Guarantor” which term includes any successor Person under the Indenture referred to in each Security Certificate representing the Securities of any
series upon which this Guarantee is endorsed (the “Indenture”)), hereby unconditionally and irrevocably guarantees to the Holders of the Securities of any series represented by each Security Certificate upon which this Guarantee is
endorsed and to the Trustee, in its individual and trust capacities, and on behalf of each such Holder, the due and punctual payment of the principal of, premium, if any, and interest and all other amounts due under the Indenture and the Securities
of any such series when and as the same shall become due and payable, whether at the Stated Maturity, by declaration of acceleration, call for redemption or otherwise, on an unsubordinated and unconditional basis according to the terms thereof and
of the Indenture referred to therein. In case of the failure of Telefónica Emisiones, S.A.U. (the “Issuer”, which term includes any successor Person under the Indenture), punctually to make any such payment of principal,
premium, if any, and interest and all other amounts due under the Indenture and on such Securities of any such series, the Guarantor hereby agrees to cause any such payment to be made punctually when and as the same shall become due and payable,
whether at the Stated Maturity or by declaration of acceleration, call for redemption or otherwise, and as if such payment were made by the Issuer. 

The Guarantor hereby further agrees that any amounts to be payable by the Guarantor under this Guarantee (whether in respect of principal,
redemption amount, interest or otherwise) will be made free and clear of and without withholding or deduction for or on account of any present or future taxes, duties, assessments or governmental charges of whatever nature imposed or levied by or on
behalf of the Kingdom of Spain or any political subdivision thereof or any authority or agency therein or thereof having power to tax, unless the withholding or deduction of such taxes, duties, assessments or governmental charges is required by law.
Subject to the exceptions set forth in Section 10.4 of the Original Indenture (as such term is defined in each Security Certificate representing the Securities of any series upon which this Guarantee is endorsed) and any Supplemental Indenture
supplementing the Original Indenture pursuant to which the Securities of any series upon which this Guarantee is endorsed have been issued, in the event that such withholding or deduction is required by law, the Guarantor shall pay such Additional
Amounts as will result in receipt by the Holders of the Securities of any such series of such amounts as would have been received by them had no such withholding or deduction been required. 

The Guarantor hereby agrees that its obligations hereunder shall be as if it were principal debtor and not merely surety, and shall be
absolute, full and unconditional, irrespective of, and shall be unaffected by, any invalidity, irregularity or unenforceability of such Securities of any such series or the Indenture, any failure to enforce the provisions of such Securities of any
such series or the Indenture, or any waivers, modification or indulgence granted to the Issuer in respect thereof by the Holders of such Securities of any such series or the Trustee or any other circumstance which may otherwise constitute a legal or
equitable discharge of a surety or guarantee; provided, however, that, notwithstanding the foregoing, no such waiver, modification or indulgence shall, without the consent of the Guarantor, increase the principal amount of such Securities of
any such series, or increase the interest rate thereon, or increase any premium payable upon redemption thereof, or change the currency of payment thereon, or change the provisions relating to payments of Additional Amounts thereon, or alter the
Stated Maturity thereof or increase the principal amount of any Original Issue Discount Security that would be due and payable upon a declaration of acceleration of the maturity thereof pursuant to Section 5.2 of the Original Indenture. The
Guarantor hereby waives diligence, presentment, demand of payment, filing of claims with a court in the event of merger or bankruptcy of the Issuer, the benefits of orden, división and excusión under Spanish law, any
right to require a proceeding first against the Issuer, protest or notice with respect to such Security or the indebtedness evidenced thereby and all demands whatsoever, and covenants that this Guarantee will not be discharged except by payment in
full of the principal of, premium, if any, and interest (including Additional Amounts, if any) on such Securities of any such series and the Guarantor shall have fully performed all its obligations in accordance with the provisions of the Securities
of any such series, this Guarantee and the Indenture; after such time, this Guarantee shall not be valid or obligatory for any purpose. 

  
 A-5 

 The Guarantor shall be subrogated to all rights of the Holders of such Securities of any
such series and the Trustee against the Issuer in respect of any amounts paid to such Holders by the Guarantor pursuant to the provisions of this Guarantee; provided, however, that the Guarantor shall not be entitled to enforce, or to receive
any payments arising out of or based upon such right of subrogation until the principal of, premium, if any, and interest (including Additional Amounts, if any) on all Securities of any such series issued under the Indenture shall have been paid in
full. 
 No reference herein to the Indenture and no provision of this Guarantee or of the Indenture shall alter or impair the guarantee of
the Guarantor, which is absolute and unconditional, of the due and punctual payment of the principal of, premium, if any, interest on, Additional Amounts, if any, and all other amounts due under the Securities of any series represented by each
Security Certificate upon which this Guarantee is endorsed. 
 The obligations of the Guarantor under this Guarantee shall, without any
further act or thing being required to be done or to occur, extend to the obligations of any successor Person who is not the Guarantor arising in respect of the Securities of any such series by virtue of a substitution pursuant to the Indenture.

 The obligations of the Guarantor under this Guarantee in respect of the Securities of any such series will constitute direct,
unconditional, unsubordinated and unsecured obligations of the Guarantor under this Guarantee and will rank pari passu without any preference among such obligations of the Guarantor under this Guarantee in respect of the Securities of any
such series and at least pari passu with all other unsubordinated and unsecured indebtedness and monetary obligations involving or otherwise related to borrowed money of the Guarantor, present and future; provided that the obligations
of the Guarantor under this Guarantee in respect of the Securities of each series will be effectively subordinated to those obligations that are preferred under Law 22/2003 (Ley Concursal) dated July 9, 2003 regulating insolvency
proceedings in the Kingdom of Spain. 
 This Guarantee shall not be valid or obligatory for any purpose until the certificate of
authentication with respect to each Security Certificate representing the Securities of any such series upon which this Guarantee has been endorsed shall have been manually executed by or on behalf of the Trustee under the Indenture. 

All capitalized terms used in this Guarantee, which are not otherwise defined herein, shall have the meanings assigned to them in the
Indenture. 
 The Guarantee shall be governed by and construed in accordance with the laws of the State of New York. 

  
 A-6 

 IN WITNESS WHEREOF, the Guarantor has caused this Guarantee to be duly executed manually or
in facsimile. 
  

							
	Dated: March 1, 2019	 		 	TELEFÓNICA, S.A.
				
		 		 	By:	 	         

		 		 	Name:	 	
		 		 	Title:	 	

  
 A-7 

 REVERSE OF SECURITY CERTIFICATE 

This Security Certificate is one of the Security Certificates representing a duly authorized issue of Fixed Rate Senior Notes due 2049 (the
“Designated Securities”), issued under an Indenture, dated as of April 20, 2018 (as amended and supplemented, the “Original Indenture”), among the Issuer, Telefónica, S.A., a sociedad
anónima incorporated under the laws of the Kingdom of Spain (herein called the “Guarantor”, which term includes any successor Person under the Indenture referred to herein), and The Bank of New York Mellon, a New York
banking corporation, as Trustee (herein called the “Trustee”, which term includes any other successor trustee under the Indenture), as supplemented with respect to the Designated Securities by the First Supplemental Indenture, dated
as of March 1, 2019 among the Issuer, the Guarantor and The Bank of New York Mellon, as Trustee, Transfer Agent, Registrar and Paying Agent (the “First Supplemental Indenture” and, together with the Original Indenture, as
supplemented, the “Indenture”) and reference is hereby made to the Indenture for a statement of the respective rights, limitations of rights, duties and immunities thereunder of the Issuer, the Guarantor, the Trustee and the Holders
of the Designated Securities and of the terms upon which each Security Certificate representing the Designated Securities is, and is to be, authenticated and delivered. 

The Designated Securities will be subject to redemption at any time upon not less than 15 nor more than 60 days’ notice, as a whole or in
part, at the election of the Issuer at a Redemption Price which is equal to: (i) with respect to any Designated Securities to be redeemed prior to the Par Call Date, the greater of: (a) 100% of the principal amount of the Designated
Securities to be redeemed plus accrued and unpaid interest thereon to, but excluding, the Redemption Date of the Designated Securities to be redeemed; and (b) as determined by the Independent Investment Banker, the sum of the present values of
the remaining scheduled payments of principal and interest on the Designated Securities being redeemed that would be due if such Designated Securities matured on the Par Call Date (exclusive of accrued and unpaid interest thereon to, but excluding,
the Redemption Date) discounted to the Redemption Date of the Designated Securities being redeemed on a semiannual basis (assuming a 360-day year consisting of twelve
30-day months) at the Treasury Rate plus 40 basis points for the Designated Securities being redeemed, plus accrued and unpaid interest on the principal amount of such Designated Securities (or any portion
thereof) being redeemed to, but excluding, the Redemption Date of the Designated Securities (or any portion thereof) being redeemed; and (ii) with respect to any Designated Securities to be redeemed on or after the Par Call Date, 100% of the
principal amount of the Designated Securities to be redeemed plus accrued and unpaid interest thereon to, but excluding, the Redemption Date of the Designated Securities to be redeemed. Any such redemption will be made in accordance with the terms
of the Indenture. 
 “Comparable Treasury Issue” means the United States Treasury security selected by an Independent
Investment Banker as having a maturity comparable to the remaining term of the Designated Securities to be redeemed (assuming for this purpose that the Designated Securities mature on the Par Call Date) that would be utilized, at the time of
selection and in accordance with customary financial practice, in pricing new issues of corporate debt securities of comparable maturity to the remaining term of the Designated Securities being redeemed. 

“Comparable Treasury Price” means, with respect to any Redemption Date prior to the Par Call Date, (1) the average of
the Reference Treasury Dealer Quotations for such Redemption Date, after excluding the highest and lowest such Reference Treasury Dealer Quotations, or (2) if the Independent Investment Banker obtains fewer than three such Reference Treasury
Dealer Quotations, the average of all such Quotations or, if only one such Quotation is obtained, such Quotation. 
 “Independent
Investment Banker” means an independent investment banking institution of national standing appointed by the Issuer and the Guarantor. 

“Par Call Date” means September 1, 2048. 

“Reference Treasury Dealer” means (1) each of Barclays Capital Inc., Goldman Sachs & Co. LLC and Merrill Lynch,
Pierce, Fenner & Smith Incorporated and their affiliates or their respective successors, provided that if any of the foregoing shall cease to be a primary U.S. government securities dealer in New York City (a “Primary
Treasury Dealer”), the Issuer and the Guarantor will substitute therefor another Primary Treasury Dealer and (2) any other Primary Treasury Dealer selected by the Issuer and the Guarantor. 

  
 A-8 

 “Reference Treasury Dealer Quotations” means, with respect to each
Reference Treasury Dealer and any Redemption Date prior to the Par Call Date, the average, as determined by the Independent Investment Banker, of the bid and asked prices for the Comparable Treasury Issue (expressed in each case as a percentage of
its principal amount) quoted in writing to the Independent Investment Banker by the Reference Treasury Dealer at 5:00 p.m. on the third New York Business Day preceding such Redemption Date. 

“Treasury Rate” means, with respect to any Redemption Date prior to the Par Call Date, the rate per annum equal to the
semi-annual equivalent yield to maturity or, if such equivalent is not available, the interpolated maturity (on a day count basis) of the Comparable Treasury Issue, calculated assuming a price for the Comparable Treasury Issue (expressed as a
percentage of its principal amount) equal to the Comparable Treasury Price for such Redemption Date. The Treasury Rate shall be calculated by the Independent Investment Banker on the third New York Business Day preceding the Redemption Date. 

The Issuer may from time to time, without the consent of the Holders of Designated Securities, create and issue further Securities having the
same terms and conditions as the previously issued Designated Securities in all respects (or in all respects except for the issue date, the first Interest Payment Date and/or the issue price), so that such further issue shall be consolidated and
form a single series with the Outstanding Designated Securities; provided, however, that any such further issuance will only be made if either such additional securities are issued with no more than de minimis original issue
discount for U.S. federal income tax purposes or any such further issuance is a “qualified reopening” as such term is defined under U.S. Treasury Regulations Section 1.1275-2(k)(3) promulgated
under the U.S. Internal Revenue Code of 1986, as amended. 
 The Designated Securities may be redeemed upon not less than 30 nor more than
60 days’ notice (ending on a day upon which interest is payable) given as provided in the Indenture, if (i) as a result of any change in the laws or regulations of the Kingdom of Spain or any political subdivision thereof or any authority
or agency therein or thereof having power to tax, or in the interpretation or administration of any such laws or regulations which becomes effective on or after the date of issuance of the Designated Securities, (x) the Issuer or the Guarantor,
as the case may be, is or would be required to pay any Additional Amounts (y) the Guarantor is or would be required to deduct or withhold tax on any payment to the Issuer to enable the Issuer to make any payment of principal, premium, if any,
or interest on the Designated Securities; provided, that such payment cannot with reasonable effort by the Guarantor be structured to avoid such deduction or withholding and (ii) such circumstances are evidenced by the delivery by the
Issuer or the Guarantor, as the case may be, to the Trustee of a certificate signed by an authorized officer or director of the Issuer or the Guarantor, as the case may be, stating that such circumstances prevail and describing the facts leading to
such circumstances, together with an opinion of independent legal advisers of recognized standing to the effect that such circumstances prevail, at a Redemption Price equal to their principal amount, together with accrued and unpaid interest, if
any, thereon to but excluding the Redemption Date. 
 If the Designated Securities are not listed on a regulated market, multilateral
trading facility or other organized market no later than 45 days prior to the first Interest Payment Date on such Designated Securities, the Issuer or the Guarantor, as the case may be, may, at its respective option and having given no less than 15
days’ notice (ending on a day which is no later than the Business Day immediately preceding such first Interest Payment Date) to the Holders of such Designated Securities and upon proper notice as provided in the Indenture, which notice shall
be irrevocable, redeem all of the Outstanding Designated Securities at a Redemption Price equal to their principal amount, together with accrued and unpaid interest, if any, thereon to but excluding the Redemption Date; provided that from and
including the issue date of such Designated Securities to and including such Interest Payment Date, the Issuer will use its reasonable best efforts to obtain or maintain such listing, as applicable. 

In the event of redemption of the Designated Securities represented by this Security Certificate in part only, a new Security Certificate
representing the unredeemed portion of the Designated Securities represented hereby will be issued and registered in the name of the Holder of the Designated Securities represented hereby upon the cancellation hereof. 

All amounts payable (whether in respect of principal, redemption amount, interest or otherwise) in respect of the Designated Securities and
the Designated Guarantee by the Issuer or the Guarantor will be made free and clear of and without withholding or deduction for or on account of any present or future taxes, duties, assessments or governmental charges of whatever nature imposed or
levied by or on behalf of the Kingdom of Spain or any political subdivision thereof or any authority or agency therein or thereof having power to tax, unless the withholding or deduction of such taxes, duties, assessments or governmental charges is
required by law. In the event that such withholding or deduction is required by law, the Issuer or the Guarantor shall pay such Additional Amounts as will 

  
 A-9 

 
result in receipt by the Holders of the Designated Securities of such amounts as would have been received by them had no such withholding or deduction been required; provided,
however, that the Issuer and the Guarantor will not be required to pay any Additional Amounts in respect of any Designated Security: 

(i)    in respect of which the Holder (or the Beneficial Owner for whose benefit it holds such Designated
Security) is liable for such taxes, duties, assessments or governmental charges in respect of such Designated Security by reason of it (or the Beneficial Owner for whose benefit it holds such Designated Security) having some connection with the
Kingdom of Spain other than (a) the mere holding of such Designated Security (or such beneficial interest) or (b) the receipt of principal, redemption amount, interest or other amount in respect of such Designated Security; 

(ii)    in respect of which the Issuer or the Guarantor have not received such documentation or information
as may be necessary to allow payments on such Designated Security to be made free and clear of Spanish withholding tax or deduction on account of Spanish taxes, including a duly executed and completed Payment Statement from the Paying Agent,
pursuant to Law 10/2014 of June 26 and Royal Decree 1065/2007 of July 27, each as amended, and any implementing legislation or regulation, or pursuant to any other law or regulation substituting or amending such law or regulation; 

(iii)    in relation to any estate, inheritance, gift, sales, transfer or similar taxes; 

(iv)    presented for payment (where presentation is required) more than 30 days after the Relevant Date
(as defined below), except to the extent that the relevant Holder would have been entitled to such Additional Amounts on presenting the same for payment on the expiry of such period of 30 days; 

(v)    presented for payment (where presentation is required) by or on behalf of a Holder (or Beneficial
Owner) who would have been able to avoid such withholding or deduction by presenting the relevant Designated Security to another paying agent; 

(vi)    in the event that the Designated Securities are redeemed pursuant to Section 2.12(b) of the
First Supplemental Indenture; or 
 (vii)    in respect of any withholding or deduction that is imposed
pursuant to Sections 1471 through 1474 of the U.S. Internal Revenue Code of 1986 and the U.S. Treasury regulations thereunder (“FATCA”), any intergovernmental agreement between the United States and any other jurisdiction
implementing or relating to FATCA, any law, regulation, guidance or interpretations enacted or issued in any jurisdiction with respect thereto, or any agreements entered into in connection with the implementation thereof; 

provided further that Additional Amounts in respect of the Designated Securities will also not be paid with respect to any payment to a Holder of any
Designated Securities who is a fiduciary, a partnership, a limited liability company or anything other than the sole Beneficial Owner of that payment, to the extent to which that payment would be required by the laws of the Kingdom of Spain (or any
political subdivision thereof or any authority or agency therein or thereof having power to tax) to be included in the income, for tax purposes, of a beneficiary or settlor with respect to the fiduciary, a member of that partnership, an interest
holder in that limited liability company or a Beneficial Owner who would not have been entitled to any Additional Amounts had it been the Holder. 

“Relevant Date” means, in respect of any payment, the date on which such payment first becomes due and payable, but if the
full amount of the moneys payable has not been received by the Paying Agent on or prior to such due date, it means the first date on which the full amount of such moneys having been so received and being available for payment to Holders, notice to
that effect is duly given to the Holders in accordance with the Indenture. 
 The foregoing provisions shall apply mutatis mutandis
to any withholding or deduction for or on account of any present or future taxes, assessments or governmental charges of whatever nature of any jurisdiction in which any successor Person to the Issuer or the Guarantor, as the case may be, is
organized, or any political subdivision or taxing authority thereof or therein, subject to exceptions equivalent to those set forth above. 

  
 A-10 

 The Indenture permits, with certain exceptions as therein provided, the amendment thereof
and the modification of the rights and obligations of the Issuer and the Guarantor and the rights of the Holders of the Securities of each series to be affected under the Indenture at any time by the Issuer, the Guarantor and the Trustee with the
consent of the Holders of a majority in principal amount of the Securities at the time Outstanding of each series to be affected. The Indenture also contains provisions permitting the Holders of specified percentages in principal amount of the
Securities of each series at the time Outstanding, on behalf of the Holders of all Securities of such series, to waive compliance by the Issuer or the Guarantor with certain provisions of the Indenture and certain past defaults under the Indenture
and their consequences. Any such consent or waiver by the Holder of the Designated Securities represented by this Security Certificate shall be conclusive and binding upon such Holder and upon all future Holders of the Designated Securities
represented by this Security Certificate and of the Designated Securities represented by any Security Certificate issued upon the registration of transfer of the Designated Securities represented by this Security Certificate or in exchange thereof
or in lieu thereof, whether or not notation of such consent or waiver is made upon this Security Certificate. 
 As set forth in, and
subject to, the provisions of the Indenture, if any Event of Default shall occur in relation to the Designated Securities (taking into account any applicable grace period), the Trustee or the Holders of not less than 25% in principal amount of the
Outstanding Designated Securities may, by written notice to the Issuer, at the Corporate Trust Office (and to the Trustee if given by the Holders), declare that the Designated Securities, including principal, any premium thereon and all interest
then accrued and unpaid on the Designated Securities, as the case may be, shall be immediately due and payable, whereupon the same shall, to the extent permitted by applicable law, become immediately due and payable at their principal amount
together with all interest, if any, accrued and unpaid thereon and premium, if any, payable in respect thereof without presentment, demand, protest or other notice of any kind, all of which the Issuer or the Guarantor, as the case may be, will
expressly waive, unless, prior thereto, all Events of Default in respect of such Designated Securities shall have been cured. 
 No
reference herein to the Indenture and no provision of the Designated Securities or of the Indenture shall alter or impair the obligation of the Issuer, which is absolute and unconditional, to pay the principal of and interest and, to the extent that
payment of such interest shall be legally enforceable, interest on any overdue principal or premium on any overdue interest, on the Designated Securities at the rate or rates herein prescribed. 

Except as set forth in the Indenture, the Designated Securities represented hereby may be transferred, in whole and not in part, only:
(i) by the Depositary to a nominee of the Depositary, (ii) by a nominee of the Depositary to the Depositary or to another nominee of the Depositary, or (iii) by the Depositary or any such nominee to a successor Depositary or a nominee
of such successor Depositary. Beneficial interests in a Designated Security represented by a Global Certificate will be exchangeable for Certificated Securities of this series only if: (a) the Depositary notifies the Issuer that it is unwilling
or unable to continue to act as Depositary or that it is no longer a clearing agency registered under the Exchange Act and, in either case, a successor Depositary is not appointed by the Issuer within 120 days after the date of such notice from the
Depositary, (b) the Issuer notifies the Trustee in writing that it has reasonably elected to cause the issuance of Certificated Securities of this series or (c) there shall have occurred and be continuing an Event of Default with respect
to the Designated Securities and the Designated Securities will be accelerated in accordance with their terms and the terms of the Indenture. Upon the occurrence of any of the events specified in (a), (b) or (c) above, Certificated
Securities of this series shall be (x) delivered by the Trustee in exchange for beneficial interest in Designated Securities represented by Global Certificates and (y) registered in such names, and issued in such authorized denominations,
as shall be requested by or on behalf of the Depositary in accordance with its customary procedures. 
 As provided in the Indenture, the
Issuer shall cause to be kept at the Corporate Trust Office of the Trustee a Register in which, subject to such reasonable regulations as it may prescribe, the Issuer shall provide for the registration of Designated Securities and of transfers of
Designated Securities. 
 No service charge shall be made for any such registration of transfer or exchange, but the Issuer or the Trustee
may require payment of a sum sufficient to cover any transfer tax or similar governmental charge payable in connection therewith other than as set forth in the Indenture. 

Prior to due presentment of this Security Certificate for registration of transfer of any Designated Security represented hereby, the Issuer,
the Guarantor, the Trustee and any agent of the Issuer, the Guarantor or the Trustee may treat the Person in whose name such Designated Security is registered as the owner of such Designated Security

  
 A-11 

 
for the purpose of receiving payment of principal of and any premium and (subject to Section 2.8 of the Original Indenture) any interest on such Designated Security and for all other
purposes whatsoever, whether or not such Designated Security be overdue, and neither the Issuer, the Guarantor, the Trustee nor any agent of the Issuer, the Guarantor or the Trustee shall be affected by notice to the contrary. 

Pursuant to Section 5-1401 of the General Obligations Law of the State of New York, the
Indenture, the Designated Securities and the Designated Guarantee shall be governed by, and construed in accordance with, the laws of the State of New York. 

The Designated Securities and this Security Certificate will be deemed to have been issued in the State of New York. 

All terms used in this Security Certificate which are not otherwise defined herein shall have the meanings assigned to them in the Indenture.

  
 A-12 

 SCHEDULE OF INCREASES OR DECREASES 

The initial principal amount of this Security Certificate is $____. The following increases or decreases in this Security Certificate have been made: 

 

									
	 Date of

Increase/Decrease
	  	 Amount of

Decrease in
 Principal Amount

of this Security

Certificate
	  	 Amount of

Increase in
 Principal Amount

of this Security

Certificate
	  	 Principal amount of this Security Certificate following such decrease or

increase
	  	 Signature of authorized signatory of Trustee or Paying

Agent

  
 A-13 

 EXHIBIT B 

PROCEDURES TO BE PERFORMED BY THE ISSUER, THE GUARANTOR AND THE PAYING AGENT IN CONNECTION WITH SPANISH LAW 10/2014, OF JUNE 26 AND ROYAL
DECREE 1065/2007, OF JULY 27 
 These procedures set forth the steps to be followed by Telefónica Emisiones, S.A.U., a
sociedad anónima unipersonal incorporated under the laws of the Kingdom of Spain (the “Issuer”), Telefónica, S.A., a sociedad anónima incorporated under the laws of the Kingdom of Spain (the
“Guarantor”), and The Bank of New York Mellon, a New York banking corporation, as paying agent (in such capacity, the “Paying Agent”, which term includes any successor Paying Agent) in connection with the Fixed Rate
Senior Notes due 2049 (the “Designated Securities”) pursuant to Section 2.14 of the First Supplemental Indenture (as defined below). The Designated Securities were issued under an Indenture, dated as of April 20, 2018 (as
amended and supplemented, the “Original Indenture”), among the Issuer, the Guarantor and The Bank of New York Mellon, as Trustee, as supplemented with respect to the Designated Securities by the First Supplemental Indenture, dated
as of March 1, 2019, among the Issuer, the Guarantor and The Bank of New York Mellon, as Trustee, Transfer Agent, Registrar and Paying Agent (the “First Supplemental Indenture” and, together with the Original Indenture, as
supplemented, the “Indenture”). All terms used in this Exhibit B which are not otherwise defined herein shall have the meanings assigned to them in the Indenture. 

“DTC” means The Depository Trust Company. 

“Payment Amount” means (i) with respect to an Interest Payment Date, the aggregate amount of interest payable on such
date, and (ii) with respect to a Redemption Date (other than a Redemption Date in respect of an early redemption of the Designated Securities pursuant to Section 2.12(b) of the First Supplemental Indenture), the aggregate amount of the
difference, if any, between the aggregate Redemption Price of the Designated Securities being redeemed on such date and the aggregate principal amount of such Designated Securities. 

“Payment Date” means an Interest Payment Date or a Redemption Date (other than a Redemption Date in respect of an early
redemption of the Designated Securities pursuant to Section 2.12(b) of the First Supplemental Indenture), as applicable. 
  

	 	(1)	 At least 15 New York Business Days prior to a Payment Date, the Issuer or the Guarantor, as the case may be,
shall (a) provide an issuer announcement to The Depository Trust Company (“DTC”) that will form the basis for a DTC important notice (the “Important Notice”) regarding the relevant payment and tax relief
entitlement information for the Designated Securities, and (b) request DTC to post such Important Notice on its website. 

  

	 	(2)	 In the case of a Redemption Date (other than a Redemption Date in respect of an early redemption of the
Designated Securities pursuant to Section 2.12(b) of the First Supplemental Indenture), no later than 5:00 p.m. New York Time on the New York Business Day prior to such Redemption Date, the Issuer or the Guarantor, as the case may be, shall
notify the Paying Agent of the Payment Amount. 

  

	 	(3)	 On or prior to each Payment Date, prior to giving the instruction referred to in step (6) or step
(7) below, as applicable, the Issuer shall deposit with the Paying Agent an amount of funds sufficient to pay the applicable Payment Amount gross of Spanish withholding tax, in accordance with Section 10.3(b) of the Original Indenture,
together with any other amounts to be deposited thereunder. 

  

	 	(4)	 No later than 1:00 a.m. New York Time on each Payment Date, the Paying Agent shall deliver an executed Payment
Statement to the Issuer and the Guarantor, which the Paying Agent shall reasonably believe to be duly completed, substantially in the form set forth in Annex I hereto, setting forth certain details relating to the Designated Securities, including
the relevant Payment Date, the Payment Amount to be paid by the Issuer and the Guarantor on such Payment Date, and the portion of the Payment Amount corresponding to each clearing agency located
outside Spain (including DTC). 

 The Payment Statement shall be dated as of the business day immediately preceding the
relevant Payment Date (“PD-1”), shall set forth information as of the close of business of PD-1 and shall be executed after the close of business of PD-1. 

  
 B-1 

	 	(5)	 The Issuer or the Guarantor, as the case may be, shall review the Payment Statement submitted by the Paying
Agent as soon as practicable. If the Issuer or the Guarantor, as the case may be, believes that the information contained in the Payment Statement is incomplete or inaccurate or that the Payment Statement is otherwise not in compliance with the
applicable regulation, it will notify the Paying Agent and state the reasons for such belief. Following such notification, the Paying Agent shall deliver to the Issuer and the Guarantor a further executed Payment Statement, revised, if necessary, as
reasonably determined by the Paying Agent and which the Paying Agent shall reasonably believe to be duly completed, as soon as possible but in any event no later than 9:30 a.m. New York Time on the relevant Payment Date (the “First Statement
Deadline”). 

  

	 	(6)	 Upon receipt of a duly executed and completed Payment Statement no later than the First Statement Deadline, the
Issuer or the Guarantor, as the case may be, shall, no later than 10:00 a.m. New York Time on the relevant Payment Date, instruct the Paying Agent to pay the Payment Amount free and clear of Spanish withholding tax. 

 

	 	(7)	 If the Paying Agent fails or for any reason is unable to deliver a duly executed and completed Payment
Statement to the Issuer and the Guarantor by the First Statement Deadline, the Issuer or the Guarantor, as the case may be, shall, no later than 10:00 a.m. New York Time on the relevant Payment Date, instruct the Paying Agent to pay the Payment
Amount net of the Spanish withholding tax applicable to such payments (currently 19%). The Paying Agent shall retain any amount so withheld (the “Amount Withheld”) until such Amount Withheld is either reimbursed to DTC Participants
pursuant to step (10) below or transferred to the Issuer pursuant to step (11) below, as applicable. In addition, the Paying Agent, no later than 11:00 a.m. New York Time on the relevant Payment Date, shall send an email to DTC at
Internationaltax@dtcc.com (or to such email address as DTC shall have notified the Paying Agent in writing) stating: “The payment of income made today on the 5.520% Fixed Rate Senior Notes due 2049 of Telefónica
Emisiones, S.A.U. (CUSIP: 87938W AX1; ISIN: US87938WAX11) was made net of Spanish withholding tax, at the rate of [indicate the applicable withholding tax rate], since the Issuer and the Guarantor did not receive a duly executed and
completed Payment Statement from the Paying Agent on a timely basis.” 

 Procedures applicable if the Paying
Agent does not deliver a duly executed and completed Payment Statement to the Issuer and the Guarantor by the First Statement Deadline 
  

	 	(8)	 If the Paying Agent fails or for any reason is unable to deliver a duly executed and completed Payment
Statement to the Issuer and the Guarantor by the First Statement Deadline, the Paying Agent undertakes to make all reasonable efforts to provide an executed Payment Statement to the Issuer and the Guarantor, which the Paying Agent shall reasonably
believe to be duly completed, as soon as possible but no later than 4:00 p.m. New York Time on the 10th calendar day of the month immediately following the relevant Payment Date (or if such day is not a New York Business Day, the first New York
Business Day immediately preceding such day). The Payment Statement shall be dated as of PD-1 and shall set forth information as of the close of business of PD-1.

  

	 	(9)	 The Issuer or the Guarantor, as the case may be, shall review the Payment Statement submitted by the Paying
Agent as soon as practicable. If the Issuer or the Guarantor, as the case may be, believes that the information contained in the Payment Statement is incomplete or inaccurate or that the Payment Statement is otherwise not in compliance with the
applicable regulation, it will notify the Paying Agent and state the reasons for such belief. Following such notification, the Paying Agent shall deliver to the Issuer and the Guarantor a further executed Payment Statement, revised, if necessary, as
reasonably determined by the Paying Agent and which the Paying Agent shall reasonably believe to be duly completed, as soon as possible but in any event no later than 5:00 p.m. New York Time on the 10th calendar day of the month immediately
following the relevant Payment Date (or if such day is not a New York Business Day, the first New York Business Day immediately preceding such day) (the “Second Statement Deadline”). 

 

	 	(10)	 If the Issuer and the Guarantor receive a duly executed and completed Payment Statement by the Second Statement
Deadline, the Issuer or the Guarantor, as the case may be, shall, no later than the 18th calendar day of the month immediately following the relevant Payment Date (or if such day is not a New York Business Day, the first New York Business Day
immediately preceding such day), instruct the Paying Agent to, within one New York Business Day of such date, transfer to each DTC Participant the portion of the Amount Withheld initially withheld from such DTC Participant for the benefit of
Beneficial Owners. 

  
 B-2 

	 	(11)	 If the Paying Agent fails or for any reason is unable to deliver a duly executed and completed Payment
Statement to the Issuer and the Guarantor by the Second Statement Deadline, the Paying Agent shall, within one New York Business Day of the date of the Second Statement Deadline, transfer the Amount Withheld to the Issuer. If this were to occur,
Beneficial Owners will have to follow the Direct Refund from Spanish Tax Authorities Procedures set forth in Annex A to the Prospectus Supplement in order to apply directly to the Spanish tax authorities for any refund to which they may be entitled.

 Original copies 
  

	 	(12)	 The Paying Agent must deliver an original copy of any duly executed and completed Payment Statement issued
hereunder to the Issuer and the Guarantor no later than the 15th calendar day of the month immediately following the relevant Payment Date. 

Notices, etc. 
 Any
notice, statement or other paper, document or communication made or given by the Issuer or the Guarantor, as the case may be, to the Paying Agent pursuant to the procedures set forth in this Exhibit B shall be sent by email or fax or communicated by
telephone, as follows (or as the Paying Agent shall have notified the others in writing): timothy.burke@bnymellon.com; Fax: +1 212 815 5366; Tel.: +1 212 815 5811. Any notice, statement or other paper, document or communication made or given
by the Paying Agent to the Issuer or the Guarantor, as the case may be, pursuant to the procedures set forth in this Exhibit B, other than a Payment Statement, shall be sent by email or fax or communicated by telephone, as follows (or as the Issuer
or the Guarantor, as the case may be, shall have notified the Paying Agent in writing): lorena.munozdomper@telefonica.com; Fax: +34 91 727 1484; Tel.: +34 91 482 3704. Non-original copies of a Payment
Statement shall be sent by email or fax to the Issuer and the Guarantor. The original copy of a duly executed and completed Payment Statement shall be sent by posted mail to the Issuer and the Guarantor at the following address: Lorena Muñoz
Domper, Distrito Telefónica, Edificio Central Plta. 2, Ronda de la Comunicación, s/n, 28050 Madrid. 

  
 B-3 

 Annex I 

Anexo al Reglamento General de las actuaciones y los procedimientos de gestión e inspección tributaria y de desarrollo de las
normas comunes de los procedimientos de aplicación de los tributos, aprobado por Real Decreto 1065/2007 
 Modelo de
declaración a que se refieren los apartados 3, 4 y 5 del artículo 44 del Reglamento General de las actuaciones y los procedimientos de gestión e inspección tributaria y de desarrollo de las normas comunes de los
procedimientos de aplicación de los tributos 
 Annex to Royal Decree 1065/2007, of 27 July, approving the General
Regulations of the tax inspection and management procedures and developing the common rules of the procedures to apply taxes 
 Declaration
form referred to in paragraphs 3, 4 and 5 of Article 44 of the General Regulations of the tax inspection and management procedures and developing the common rules of the procedures to apply taxes 

Don (nombre), con número de identificación fiscal (...)(1), en nombre y
representación de (entidad declarante), con número de identificación fiscal (....)(1) y domicilio en (...) en calidad de (marcar la letra que proceda): 

Mr. (name), with tax identification number (...)(1), in the name and on behalf of (entity), with
tax identification number (....)(1) and address in (...) as (function - mark as applicable): 
  

	(a)	 Entidad Gestora del Mercado de Deuda Pública en Anotaciones. 

 

	(a)	 Management Entity of the Public Debt Market in book entry form. 

 

	(b)	 Entidad que gestiona el sistema de compensación y liquidación de valores con sede en el
extranjero. 

  

	(b)	 Entity that manages the clearing and settlement system of securities resident in a foreign country.

  

	(c)	 Otras entidades que mantienen valores por cuenta de terceros en entidades de compensación y
liquidación de valores domiciliadas en territorio español. 

  

	(c)	 Other entities that hold securities on behalf of third parties within clearing and settlement systems domiciled
in the Spanish territory. 

  

	(d)	 Agente de pagos designado por el emisor. 

 

	(d)	 Issue and Paying Agent appointed by the issuer. 

Formula la siguiente declaración, de acuerdo con lo que consta en sus propios registros: 

Makes the following statement, according to its own records: 
  

	1	 En relación con los apartados 3 y 4 del artículo 44: 

 

	1	 In relation to paragraphs 3 and 4 of Article 44: 

 

	1.1	 Identificación de los
valores........................................................................ 

  

	1.1	 Identification of the
securities........................................................................ 

  

	1.2	 Fecha de pago de los rendimientos (o de reembolso si son valores emitidos al descuento o segregados)

  

	1.2	 Income payment date (or refund if the securities are issued at discount or are segregated)

  

	1.3	 Importe total de los rendimientos (o importe total a reembolsar, en todo caso, si son valores emitidos al
descuento o segregados).............................................................................. 

 

	1.3	 Total amount of income (or total amount to be refunded, in any case, if the securities are issued at discount
or are segregated) 

  
 B-4 

	1.4	 Importe de los rendimientos correspondiente a contribuyentes del Impuesto sobre la Renta de las Personas
Físicas, excepto cupones segregados y principales segregados en cuyo reembolso intervenga una Entidad
Gestora........................................................................ 

  

	1.4	 Amount of income corresponding to Personal Income Tax taxpayers, except segregated coupons and segregated
principals for which reimbursement an intermediary entity is involved.................. 

  

	1.5	 Importe de los rendimientos que conforme al apartado 2 del artículo 44 debe abonarse por su importe
íntegro (o importe total a reembolsar si son valores emitidos al descuento o segregados). 

  

	1.5	 Amount of income which according to paragraph 2 of Article 44 must be paid gross (or total amount to be
refunded if the securities are issued at discount or are segregated). 

  

	2	 En relación con el apartado 5 del artículo 44. 

 

	2	 In relation to paragraph 5 of Article 44. 

 

	2.1	 Identificación de los
valores........................................................................ 

  

	2.1	 Identification of the
securities........................................................................ 

  

	2.2	 Fecha de pago de los rendimientos (o de reembolso si son valores emitidos al descuento o segregados)

  

	2.2	 Income payment date (or refund if the securities are issued at discount or are segregated)

  

	2.3	 Importe total de los rendimientos (o importe total a reembolsar si son valores emitidos al descuento o
segregados................................................................................. 

 

	2.3	 Total amount of income (or total amount to be refunded if the securities are issued at discount or are
segregated) 

  

	2.4	 Importe correspondiente a la entidad que gestiona el sistema de compensación y liquidación de
valores con sede en el extranjero A. 

  

	2.4	 Amount corresponding to the entity that manages the clearing and settlement system of securities resident in a
foreign country A. 

  

	2.5	 Importe correspondiente a la entidad que gestiona el sistema de compensación y liquidación de
valores con sede en el extranjero B. 

  

	2.5	 Amount corresponding to the entity that manages the clearing and settlement system of securities resident in a
foreign country B. 

  

	2.6	 Importe correspondiente a la entidad que gestiona el sistema de compensación y liquidación de
valores con sede en el extranjero C. 

  

	2.6	 Amount corresponding to the entity that manages the clearing and settlement system of securities resident in a
foreign country C. 

 Lo que declaro en ........................a .... de ...............de
.... 
 I declare the above in ............... ... on the.... of............... ... of.... 

 

	(1) 	 En caso de personas, físicas o jurídicas, no residentes sin establecimiento permanente se
hará constar el número o código de identificación que corresponda de conformidad con su país de residencia 

  

	(1)	 In case of non-residents (individuals or corporations) without
permanent establishment in Spain it shall be included the number or identification code which corresponds according to their country of residence. 

  
 B-5

Source: [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00292-of-00352.parquet"}, [{"source": "alea-institute/alea-institute/kl3m-data-edgar-agreements/train-00292-of-00352.parquet"}]]