Document:

Exhibit 10.57

 

TENTH
AMENDMENT TO LEASE ASSIGNMENT, ASSUMPTION, and CONSENT TO ASSIGNMENT

 

THIS
TENTH AMENDMENT TO LEASE, ASSIGNMENT, ASSUMPTION, AND CONSENT TO ASSIGNMENT (the “Tenth Amendment to Lease”),
made as of the 15th day of July, 2014, by and between SOUTHPORT BUSINESS PARK LIMITED PARTNERSHIP, a North Carolina limited
partnership (the “Landlord”), and GENTRIS CORPORATION, a Delaware corporation (the “Assignor”)
and GENTRIS, LLC, a Delaware limited liability company ( the “Assignee”).

 

WITNESSETH

 

A. WHEREAS,
Landlord and Assignor, as Tenant, entered into a certain Lease Agreement dated as of June 12, 2004, amended by letter agreement
dated October 21, 2004, by Second Amendment to Lease dated June 17, 2005, by Letter Agreement dated September 19, 2005, by Third
Amendment to Lease dated May 25, 2006, by Fourth Amendment to Lease dated December 20, 2007, by Fifth Amendment to Lease dated
June 15, 2009, by Sixth Amendment to Lease dated June 3, 2010, by Seventh Amendment to Lease dated October 26, 2010, by Eighth
Amendment to Lease (the “Eighth Amendment”) dated July 29, 2011 and the Ninth Amendment to Lease dated November 7,
2012 (collectively, the “Lease”), a copy of which is attached as Exhibit A, for certain space known as Suite 400,
in the Building located at 133 Southcenter Court, Morrisville, Wake County, North Carolina, as more particularly described in
the Lease; and

 

B. Pursuant
to and in connection with a certain transaction involving Assignor and Assignee (the “Transaction”), all of Assignor’s
right, title and interest in and to the Lease is being acquired by and assigned to Assignee as of the effective date of the Transaction
(the “Transaction Effective Date”), which is anticipated to occur on or before July 15, 2014.

 

C. In
connection with the Transaction, the Lease requires the Landlord to consent to such assignment.

 

D. The
Landlord and Assignee in conjunction with this Transaction wish to extend the term of the Lease, and set forth the Monthly Minimum
Rent for the extended term along with amending certain other terms of the Lease;

 

NOW
THEREFORE, in consideration of the premises contained herein, the sum of Ten Dollars ($10.00) and other good and valuable consideration,
the mutual receipt and sufficiency of which is hereby acknowledged, the parties agree to amend the Lease as follows:

 

1.
 Assignment, Assumption, and Consent: As of the Transaction Effective Date, Assignor
hereby assigns and transfers unto Assignee all of Assignor’s rights, title and interest as Tenant in and to the Lease. Assignee
hereby accepts this Assignment and agrees to assume and be bound by and to perform all of the duties and obligations as Tenant
under the Lease, and shall be liable to Landlord for the performance thereof. After the Transaction Effective Date, all references
in the Lease to Tenant shall mean the Assignee. Assignor shall not be released from any obligations or duties under the Lease
and shall remain fully liable thereon notwithstanding this Assignment. As part of the assignment, Assignor will assign its current
Security Deposit with a balance of $22,726.73 to Assignee and any future refund of the Security Deposit, if any, shall be made
exclusively to Assignee. The Landlord hereby consents to the assignment and assumption of this Lease. Assignor and Assignee agree
and acknowledge that the Demised Premises shall be used for the use as defined in the Lease, and for no other purpose whatsoever
without the written consent of Landlord.

 

2. Notices:
Assignor’s address for purposes of notice and for all other purposes under the Lease shall be:

 

c/o
Hughes Pittman & Gupton, LLP

1500 Sunday Drive, Suite 300

Raleigh, NC 27607 Telephone: 919-232-5900

Facsimile: 919-232-5901

Attention: Tim C. Gupton

 

Assignee’s
address for purposes of notice and for all other purposes under the Lease shall be:

 

c/o
Cancer Genetics, Inc.

Meadows Office Complex

201 Route 17 North, 2nd Floor

Rutherford, NJ 07070

Telephone: 201-529-9200

Facsimile: 201-528-9201

Attention: Panna Sharma, President

 

3. Conditions
Precedent. Notwithstanding anything to the contrary, this Tenth Amendment to Lease shall become effective only upon receipt
by Landlord of written notice of the consummation of the Transaction from Assignor, and if such notice is not received by Landlord
on or before October 1, 2014, this Tenth Amendment to Lease shall be null and void.

 

    	 	 	 

    	 

    

 

4. In
connection with the extension of the Lease term and setting forth of Monthly Minimum Rents, Landlord and Tenant agree to the following:

 

	 	a.	Page
    Two - Section 1.02 - Term of the Lease. Delete “May 31, 2019” and insert “May 31, 2020” in its
    place.
	 	 	 
	 	b.	Page
    Three - Section 1.04 - Monthly Minimum Rent and Adjusted Monthly Minimum Rent. At the end of the rent table that states:

 

	Date Range	 	Rentable 

Square Feet	 	 	Minimum

 Annual Rent	 	 	Monthly

 Minimum Rent	 	 	Per Rentable

 Square Foot	 
	06/01/2018 Through 05/31/2019	 	 	24,906	 	 	$	316,272.40	 	 	$	26,356.03	 	 	$	12.70	 

 

Insert
the following:

 

	Date Range	 	Rentable 

Square Feet	 	 	Minimum

 Annual Rent	 	 	Monthly

 Minimum Rent	 	 	Per Rentable

 Square Foot	 
	06/01/2019 Through 05/31/2020	 	 	24,906	 	 	$	324,179.21	 	 	$	27,014.93	 	 	$	13.07	 

 

	 	c.	Page
    Four - Section 1.06 - Rent Abatement. Add the following at the end of Section 1.06:
	 	 	 
	 	 	Notwithstanding
    the rent chart set forth in Section 2 of the Eight Amendment to Lease, Twelve Thousand Dollars ($12,000.00) monthly of the
    Monthly Minimum Rent due for each of the months from July, 2014 through December, 2014 shall be abated (the “Tenth Amendment
    Abatement Months”). During the Tenth Amendment Abatement Months, Tenant shall continue to pay the balance of Eleven
    Thousand Eight Hundred Seventy-seven and 27/100 Dollars ($11,877.27) monthly of the Monthly Minimum Rent along with all Direct
    Expenses due under the Lease. The entire Monthly Minimum Rent that was abated for the Tenth Amendment Abatement Months, along
    with any previous Rent Abatement afforded by the Lease shall immediately become due and payable upon the occurrence of an
    Event of Default past all applicable cure periods, by Tenant under the Lease.
	 	 	 
	 	d.	Termination
    of all Rights of First Offer, Rights of First Refusal, and Expansion Rights: All rights contained in the Lease and its
    amendments that give Tenant any rights to spaces in the Property other than the Demised Premises are hereby terminated. This
    includes, but is not limited to the following:

 

	 	(i)	Sixth
    Amendment to Lease - Section 8 - Contingent Space. This section is deleted in its entirety.
	 	 	 
	 	(ii)	Eighth
    Amendment to Lease - Section 11 - Right of First Offer. This section is deleted in its entirety.
	 	 	 
	 	(iii)	Eight
    Amendment to Lease - Section 12 - Right of First Refusal. This section is deleted in its entirety.
	 	 	 
	 	(iv)	Ninth
    Amendment to Lease - Section 2. This section is deleted in its entirety.

 

		e.	At
                                         Landlord’s request with ninety (90) days prior written notice from Landlord, Tenant
                                         agrees to relinquish any or all of that part of the Demised Premises identified as the
                                         Third Expansion Space on the Eighth Amendment to Lease (that being the Four Thousand
                                         Three Hundred Fifty (4,350) rentable square feet) as shown on Exhibit A of the Eighth
                                         Amendment to Lease (the “Relinquished Portion”). The Monthly Minimum Rent
                                         will be reduced based on the size of the Relinquished Portion on a per square foot basis
                                         effective as of the date that Landlord takes possession of the Relinquished Portion.
                                         In addition, the Direct Expenses will be reduced to reflect the decreased square footage
                                         of the Demised Premises and its pro-rata share. Landlord will pay for the costs of separating
                                         the Relinquished Portion from the Demised Premises.

 

5. Assignor
and Assignee warrant there have been no dealings with any broker other than Aldene E. “Dee” Creech Osborne of NAI
Carolantic Realty, Inc. in connection with this Tenth Amendment to Lease.

 

6. This
Tenth Amendment to Lease may be executed in counterparts, each of which when so executed shall be deemed to be an original and
such counterparts shall together be constitute and be one and the same instrument. Counterpart signatures need not be on the same
page and shall be deemed effective upon receipt.

 

7. Except
as herein amended, the terms and conditions of the Lease shall remain in full force and effect. Each person signing as Landlord,
Assignor or Assignee warrants and represents that she or he is authorized to execute and deliver this Tenth Amendment to Lease
and to make it a binding obligation of Landlord, Assignor or Assignee. Capitalized terms not otherwise defined in this Tenth Amendment
to Lease shall have the meaning set forth in the Lease.

 

    	 	-2-	 

    	 

    

 

IN
WITNESS WHEREOF, the parties hereto have caused this instrument to be executed the date and year first above written.

 

	 	LANDLORD:
	 	 
	 	SOUTHPORT
    BUSINESS PARK LIMITED PARTNERSHIP, a North Carolina limited partnership
	 	 	 
	 	By:	SOUTHPORT
    BUSINESS PARK INVESTORS CORPORATION, a North Carolina corporation, 

its general partner
	 	 	 
	 	By:	 
	 	 	Richard
    G. Sullivan
	 	 	Vice
    President
	 	 	 
	 	ASSIGNOR:
	 	 
	 	GENTRIS
    CORPORATION, 
	 	a
    Delaware corporation
	 	 	 
	 	By:
    	 
	 	Name:
    	 
	 	Title:	 
	 	 	 
	 	ASSIGNEE:
	 	 
	 	GENTRIS
    LLC,
	 	a
    Delaware limited liability company
	 	 	 
	 	By:
    	 
	 	Name:	 
	 	Title:	 

 

    	 	-3-	 

    	 

    

 

EXHIBIT
A - Lease

 

[Intentionally
omitted]Exhibit
10.58

 

STATE
OF NORTH CAROLINA

 

ASSIGNMENT
OF LEASE

 

COUNTY
OF WAKE

 

THIS
ASSIGNMENT OF LEASE (“Assignment”) is entered into and effective this 15th day
of July, 2019· (“Effective Date”) by and between Cancer Genetics, Inc., a Delaware corporation, successor-in-interest
to Gentris, LLC, a Delaware limited liability company, (hereinafter the “Assignor”) and Interpace BioPharma, Inc.,
a Delaware corporation (hereinafter the “Assignee”), with the consent of Southport Business Park Limited Partnership,
a North Carolina limited partnership (hereinafter the “Landlord”).

 

W
I T N E S S E T H:

 

WHEREAS,
Assignor, successor-in-interest to Gentris, LLC, successor-in-interest to Gentris Corporation, who as tenant, previously entered
into a certain lease agreement dated as of June 12, 2004, as amended by letter agreement dated October 21, 2004, by Second Amendment
to Lease dated June 17, 2005, by Letter Agreement dated September 19, 2005, by Third Amendment to Lease dated May 25, 2006, by
Fourth Amendment to Lease dated December 20, 2007, by Fifth Amendment to Lease dated June 15, 2009, by Sixth Amendment to Lease
dated June 3, 2010, by Seventh Amendment to Lease dated October 26, 2010, by Eighth Amendment to Lease dated July 29, 2011, by
Ninth Amendment to Lease dated November 7, 2012 and by Tenth Amendment to Lease dated July 15, 2014 (collectively, the “Lease”)
with Landlord for certain premises located at 133 Southcenter Court, Suite 400, Morrisville, North Carolina 27650 (“Premises”);
and

 

WHEREAS,
as of the Effective Date, Assignor owes Landlord the amount of $79,323.70 (“Outstanding Balance”) pursuant to the
terms of the Lease.

 

WHEREAS,
Assignor is desirous of assigning all of its rights and responsibilities under the Lease to the Assignee consistent with the terms
and conditions set forth herein; and

 

WHEREAS,
Assignee desires to assume all of Assignor’s obligation under the Lease consistent with the terms and conditions set forth
herein;

 

WHEREAS,
Assignor and Assignee desire to obtain Landlord’s consent in connection therewith; and

 

NOW,
THEREFORE, for good and valuable consideration, the receipt and adequacy of which is hereby acknowledged and agreed, the parties
hereto agree as follows:

 

1.
Assignment. For good and valuable consideration, the receipt and adequacy of which are hereby acknowledged by Assignor,
as of the Effective Date, Assignor hereby assigns and transfers unto Assignee all of Assignor’s rights, title and interest
as Tenant in and to the Lease. As a material inducement for Assignee to execute this Assignment, Assignor represents and warrants
to Assignee that Assignor has not previously assigned or encumbered all or any portion of Assignor’s right, title and interest
arising under the Lease and that upon receipt of the Outstanding Balance and the Administrative Fee (as defined in Section 19
below) by Landlord, Assignor will not be in default in the performance of any of Assignor’s obligations under the Lease.

 

    	 

     

    

 

2.
Assumption. Assignee hereby accepts this Assignment and agrees to assume and be bound by and to perform all duties and
obligations as Tenant under the Lease, and shall be liable to Landlord for the performance thereof. Assignee hereby acknowledges
receipt of a fully executed copy of the Lease from Assignor.

 

3.
Consent to Assignment and Waiver of Termination Rights. Landlord hereby: (i) acknowledges and consents, for purposes of
Section 13.01 of the Lease, to the assignment of this Lease by Assignor to Assignee pursuant to the terms of this Assignment,
and waives any applicable termination or other rights under the Lease arising solely in connection with this Assignment, (ii)
asserts that, to the best of Landlord’s knowledge, the Lease is in full force and effect and (iii) acknowledges that, upon
receipt by Landlord of the full Outstanding Balance and the Administrative Fee, there is no default of Assignor under the Lease
which has remained uncured after any applicable period for notice and cure and no circumstance or set of circumstances exists
(including this Assignment) which, with the giving of notice or the passage of time, or both, would constitute a default under
the Lease.

 

4.
No Modification of Use. Assignor and Assignee agree and acknowledge that the Premises shall be used for the use as defined
in the Lease, and for no other purpose whatsoever without the written consent of Landlord.

 

5.
No Default. Neither Assignor nor any guarantor of the Original Lease shall be released from any obligations or duties under
the Lease and shall remain fully liable thereon notwithstanding this Assignment.

 

6.
Entire Agreement. This Assignment contains the entire agreement of Assignor and Assignee with respect to the subject matter
hereof.

 

7.
Notices. All notices to Assignee as Tenant under the Lease shall be delivered to:

 

Interpace
BioPharma, Inc.

c/o
Morris Corporate Center 1, Building C

300
Interpace Parkway

Parsippany,
New Jersey 07054

Attention:
Jack E. Stover, President & CEO

Telephone:
412-224-6100

 

Email:
jstover@interpacedx.com

 

All
notices to the Assignor shall be delivered to:

 

Cancer
Genetics, Inc.

201
Route 17 North, 2nd Floor

Rutherford,
New Jersey 07070

Attention:
Jay Roberts, President & CEO

Telephone:
201-528-9200

Facsimile:
201-528-920

 

Email:
Jay.Roberts@CGI.com

 

    	 

     

    

 

8.
Security Deposit. As part of the assignment, Assignor will assign its current security deposit balance with Landlord in
the amount of $22,726.73 to Assignee and upon the effectiveness of this agreement any future refund of the deposit,
if any, shall be made exclusively to Assignee. In addition, simultaneously upon the execution of this Assignment, Assignee shall
deposit the additional sum of $11,190.77 as additional security deposit with Landlord so that as of the Effective
Date, the security deposit on hand shall be $33,917.50.

 

9.
No Other Amendment. Except as set forth herein, the Lease shall remain in full force and effect, and shall be binding and
enforceable against Assignor and Assignee and Landlord. Except as otherwise set forth herein, capitalized terms shall have the
meanings attributed to them in the Lease.

 

10.
Guaranty of Lease. Simultaneously upon the execution of this Assignment, Assignee shall cause Interpace Diagnostics Group,
Inc., a Delaware corporation, to sign a guaranty of lease in the same form as that guaranty of lease attached hereto as Exhibit
A.

 

11.
Counterparts. This Assignment may be executed in counterparts, each of which shall be deemed an original, but all of which
together shall constitute one and the same agreement.

 

12.
Binding Effect. This Assignment shall be binding upon and inure to the benefit of the parties hereto and their respective
successors and assigns.

 

13.
Governing Law. This Assignment shall be construed and interpreted under, and governed and enforced according to, the laws
of the State of North Carolina. The parties hereto hereby submit to the jurisdiction of the courts of the State of North Carolina
in the event of any action or dispute arising hereunder.

 

14.
Headings and Construction. The headings set forth in this Assignment are inserted only for convenience and are not in any
way to be construed as part of this Assignment or a limitation on the scope of the particular section to which it refers.

 

15.
Authority. Landlord, Assignor, Assignee and Guarantor warrant and represent that the individual executing this Assignment
on behalf of such entity is authorized to execute and deliver this Assignment and to make it a binding obligation of Landlord,
Assignor, Assignee and Guarantor. This Assignment shall be binding upon the respective parties hereto, and upon their heirs, executors,
successors and assigns.

 

    	 

     

    

 

16.
No Options or Inducements: Condition of Premises. Assignee acknowledges and agrees that, as of the Effective Date and notwithstanding
anything to the contrary set forth in the Lease or this Assignment, Assignee shall have no extension, renewal, termination or
other options whatsoever with regard to the Premises or under the Lease. Assignee further acknowledges and agrees that Assignee
is not and shall not be entitled to any allowances, concessions, upfit work or other inducements of any kind in connection with
the Premises or under the Lease. In the latter regard, Assignee acknowledges and agrees that from and after the Effective Date,
Landlord is leasing the Premises to Assignee “as is,” without any representations or warranties of any kind (including,
without limitation, any express or implied warranties of merchantability, fitness or habitability) and without any obligation
on the part of Landlord to alter, remodel, improve or decorate the Premises or any part thereof.

 

17.
Acknowledgment of Non-Existence of Claims and Waiver. Assignor and Assignee acknowledges that as of the Effective Date,
there are no claims by Assignor or Assignee against Landlord arising under the Lease. Assignor and Assignee release and discharge
Landlord, and its successors and assigns, from any demands for injuries or damages of any kind or nature arising out of or related
to the Lease or the Premises that occurred on or prior to the Effective Date.

 

18.
Brokerage. Assignor and Assignee represent to Landlord that neither Assignor nor Assignee have entered into any agreements
with any brokers in connection with this Assignment. Assignor and Assignee indemnify, hold harmless and agree to defend Landlord,
its members, principals, partners, officers, directors, employees and agents and the respective principals, officers and directors
of any such agents from and against any and all claims of any brokers claiming to have represented Assignor or Assignee in connection
with this Assignment.

 

19,
Administrative Fee. On or prior to the Effective Date, Assignor shall pay the sum of $1,500.00 to Landlord to compensate
Landlord for legal fees, cost of administration, and other expenses incurred in connection with the negotiation and processing
of this Assignment (“Administrative Fee”). To the extent Assignor fails to compensate Landlord for such Administrative
Fee, Assignee shall be responsible for such fee within five (5) days of an invoice from Landlord.

 

20.
Counterparts. This Agreement may be executed in any number of counterparts with the same effect as if all signing parties
had signed the same document. All counterparts shall be construed together and constitute the same instrument. Such counterparts
may be transmitted electronically and any such electronically transmitted counterparts shall be deemed to be an original executed
counterpart.

 

[SIGNATURE
PAGE TO FOLLOW]

 

    	 

     

    

 

IN
WITNESS WHEREOF, the parties have set their hands as of the day and year first above written.

 

	 	 	 	ASSIGNOR:
	 	 	 	 
	 	 	 	CANCER
    GENETICS, Inc.,
	 	 	 	a
    Delaware corporation
	 	 	 	 	 
	 	 	 	/s/
    John A. Roberts
	 	 	 	By:	John
    A. Roberts
	 	 	 	Its:	President
    & CEO
	 	 	 	 	 
	 	 	 	ASSIGNEE:
	 	 	 	 
	 	 	 	INTERPACE
    BIOPHARMA, INC.,
	 	 	 	a
    Delaware corporation
	 	 	 	 	 
	 	 	 	/s/
    Jack E. Stover
	 	 	 	By:	Jack
    Stover 
	 	 	 	Its:	President
    & Chief Executive Officer
	 	 	 	 	 
	Acknowledged
    and Agreed to by: 	 	 	 
	 	 	 	 	 
	GENTRIS,
    LLC, 	 	 	 
	a
    Delaware limited liability company	 	 	 
	 	 	 	 	 
	/s/
    John A. Roberts	 	 	 
	By:	John
A. Roberts	 	 	 
	Its:	President & CEO	 	 	 

 

[REMAINDER
OF PAGE INTENTIONALLY LEFT BLANK]

 

[Signature
Page to Assignment of NC Lease]

 

    	 

     

    

 

ACKNOWLEDGEMENT
AND CONSENT OF GUARANTOR

 

For
good and valuable consideration, the receipt and sufficiency of which are hereby acknowledged, the guarantor of the Lease hereby
acknowledges and consents to the terms of this Assignment and reaffirms its obligations under that certain Unconditional Guaranty
of Lease effective July 15, 2014 in favor of Landlord.

 

	 	GUARANTOR:
	 	 
	 	CANCER
    GENETICS, Inc.,
	 	a
    Delaware corporation
	 	 
	 	/s/
    John A. Roberts
	 	By:
    	John
    A. Roberts
	 	Its:
    	President
    & CEO

 

    	 

     

    

 

ACKNOWLEDGEMENT
AND CONSENT OF LANDLORD:

 

Landlord
has acknowledges and consents to the above referenced Assignment as of the Effective Date.

 

	 	LANDLORD:
	 	 
	 	Southport
    Business Park Limited Partnership,
	 	a
    North Carolina limited partnership
	 	 
	 	By: Southport Business Park Investors Corporation, general
    partner
	 	 
	 	/s/
    Richard G. Sullivan
	 	Richard G. Sullivan, Vice President

 

    	 

     

    

 

EXHIBIT
A

 

Guaranty
of Lease

 

[Intentionally omitted.]

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