Document:

EX-10.7

 Exhibit 10.7 

EMPLOYMENT AGREEMENT 
 This
EMPLOYMENT AGREEMENT (this “Agreement”) is made and entered into as of this 17th day of February, 2016 by and between Albireo, Inc., a Delaware corporation (the “Company”), and Peter A. Zorn (the
“Executive”), effective as of July 11, 2015 (the “Effective Date”).
 RECITALS 

The Company desires to employ the Executive and the Executive desires to be employed on the terms and conditions set forth in this
Agreement. In consideration of the foregoing premises and the mutual promises, terms, provisions and conditions set forth in this Agreement, the parties hereby agree: 

1. Employment. Subject to the terms and conditions set forth in this Agreement, the Company hereby offers and the Executive
hereby accepts employment. 
 2. Term. This Agreement will continue in effect until terminated in accordance with Section 5. The
term of this Agreement is hereafter referred to as “the term of this Agreement” or “the term hereof.” 

3. Capacity and Performance. 

(a) During the term hereof, the Executive shall serve the Company and Albireo Limited (including any successor thereto,
“Parent”) as their General Counsel and Senior Vice President, Corporate Development. In addition, and without further compensation, the Executive shall serve as a director and/or officer of the Company and/or one or more of the
Company’s Affiliates if so elected or appointed from time to time. 
 (b) During the term hereof, the Executive shall be employed by
the Company on a full-time basis and shall perform the duties and responsibilities of his position and such other duties and responsibilities on behalf of the Company and its Affiliates as reasonably may be designated from time to time by the Chief
Executive Officer of Parent (the “CEO”). The Executive shall be a member of the executive leadership team for the Company and Parent (the “ELT”), as such team may be characterized from time to time. The
Executive’s principal work location shall be in Boston, MA. 

 (c) During the term hereof, the Executive shall devote his full business time and his best
efforts, business judgment, skill and knowledge exclusively to the advancement of the business and interests of the Company and its Affiliates and to the discharge of his duties and responsibilities hereunder. The Executive shall not engage in any
other business activity or serve in any industry, trade, professional, governmental or academic position during the term of this Agreement, except as may be expressly approved in advance by the CEO in writing; provided, however, that the Executive
may without advance consent participate in charitable activities and passive personal investment activities, provided that such activities do not, individually or in the aggregate, interfere with the performance of the Executive’s duties under
this Agreement, are not in conflict with the business interests of the Company or any of its Affiliates and do not violate Sections 7, 8 or 9 of this Agreement. 

(d) During the term hereof, the Executive shall comply with all Company policies, practices and procedures and all codes of ethics or
business conduct applicable to the Executive’s position, as in effect from time to time. 
 4. Compensation and
Benefits. As compensation for all services performed by the Executive hereunder during the term hereof, and subject to performance of the Executive’s duties and responsibilities to the Company and its Affiliates, pursuant to this
Agreement or otherwise: 
 (a) Base Salary. During the term of this Agreement, the Company shall pay the Executive a base salary
at the rate of Two Hundred Seventy Thousand Dollars ($270,000) per year, payable monthly in equal amounts in accordance with the normal payroll practices of the Company as in effect from time to time and subject to adjustment upward, but not
downward, from time to time by the Parent’s board of directors (the “Board”), in its sole discretion. Such base salary, as from time to time adjusted, is hereafter referred to as the “Base
Salary.” The Executive hereby consents to the direct deposit of any payments made by the Company under this Agreement into his designated U.S. bank account, and agrees to complete the paperwork necessary to allow for such direct
deposit. 
 (b) Annual Bonus Compensation. For each fiscal year completed during the term hereof, pro-rated for the partial
initial fiscal year of employment, the Executive shall be eligible to participate in any annual bonus plan provided by the Company (or Parent) for its executives generally, as in effect from time to time. The Executive’s annual target
bonus shall be thirty percent (30%) of the Base Salary, subject to adjustment upward, but not downward, from time to time by the Board in its sole discretion (the “Target Bonus”), with the actual amount of the bonus, if any, to be
determined by the Board (or, to the extent permitted or required by applicable law, regulation or stock exchange requirement, a compensation or remuneration committee thereof) or the CEO in accordance with applicable performance criteria reasonably

 
established by the Board. In order to earn an annual bonus under this Section 4(b) for any fiscal year, the Executive must be employed by the Company on the last date of the applicable
fiscal year. Any annual bonus payable hereunder will be paid at the same time as such bonuses are paid to other members of the ELT, but in no event later than two and one-half months following the end of the fiscal year for which the bonus is
earned.
 (c) Vacations. During the term hereof, the Executive shall be entitled to four (4) weeks of vacation per annum,
accrued ratably, to be taken at such times and intervals as shall be determined by the Executive, subject to the reasonable business needs of the Company. Vacation shall otherwise be governed by the policies of the Company, as in effect from
time to time. 
 (d) Employee Benefit Plans. During the term hereof and subject to any contribution therefore generally
required of similarly-situated employees of the Company, the Executive shall be entitled to participate in any and all Employee Benefit Plans from time to time in effect for similarly-situated employees of the Company generally, including any
short-term disability plan, long term disability and 401(k) retirement savings plan, except to the extent any Employee Benefit Plan provides for benefits otherwise provided to the Executive hereunder (e.g., a severance pay plan). Such
participation shall be subject to (i) the terms of the applicable plan documents and (ii) generally applicable Company policies. For purposes of this Agreement, “Employee Benefit Plan” shall have the meaning ascribed to such
term in Section 3(3) of ERISA, as amended from time to time. The Executive shall have no recourse against the Company under this Agreement in the event that the Company should alter, modify, add to or eliminate any or all of its Employee
Benefit Plans.
 (e) Business Expenses. The Company shall pay or reimburse the Executive for reasonable, customary and
necessary business expenses incurred or paid by the Executive in the performance of his duties and responsibilities hereunder, subject to such reasonable substantiation and documentation and to travel and other policies as may be required by the
Company from time to time. 
 (f) Stock Options. The Executive shall receive a stock option grant of at least 1% of the
outstanding shares of Parent on a fully diluted basis under an equity program sponsored by Parent, subject to the terms of the program. All rights to purchase capital stock (e.g., stock options, compensatory warrants, restricted stock or the
like) of Company or Parent held by the Executive from to time (collectively, “Options”) that are outstanding prior to a Change of Control (as defined below) shall, to the extent unvested or subject to vesting-like restrictions, be
fully vested and exercisable (and any vesting-like restrictions shall lapse in full) in the case of each such Option (i) at the time set forth in the equity program under which such Option was granted (and in accordance with the terms of such
program) or (ii) if earlier, upon the Change of Control. The foregoing sentence shall be (A) deemed incorporated into each option or similar agreement evidencing awards made to the Executive after the Effective Date and (B) without prejudice to
the Executive’s right to any earlier acceleration of vesting, continued period of vesting or post-termination rights for the Executive provided for in the applicable program under which such Option was granted or under applicable law.

 5. Termination of Employment and Severance Benefits. The Executive’s employment
hereunder shall terminate under the following circumstances: 
 (a) Death. In the event of the Executive’s death during the
term hereof, the date of death shall be the date of termination, and the Company shall pay or provide to the Executive’s designated beneficiary or, if no beneficiary has been designated by the Executive in a notice received by the Company, to
his estate: (i) any Base Salary earned but not paid through the date of termination, (ii) pay for any vacation time earned but not used through the date of termination, (iii) any business expenses incurred by the Executive but unreimbursed on
the date of termination, provided that such expenses and required substantiation and documentation are submitted within sixty (60) days following termination, that such expenses are reimbursable under Company policy, and that any such expenses
subject to Section 5(f)(iv) shall be paid not later than the deadline specified therein; and (iv) any annual bonus earned but not paid for the fiscal year preceding the fiscal year in which the date of termination occurs (all of the foregoing,
payable subject to the timing limitations described herein, “Final Compensation”). The Company shall have no further obligation or liability to the Executive. Other than business expenses described in Section 5(a)(iii),
Final Compensation shall be paid to the Executive’s designated beneficiary or estate at the time prescribed by applicable law and in all events within thirty (30) days following the date of death. 

(b) Disability.
 (i) The
Company may terminate the Executive’s employment hereunder, upon notice to the Executive, in the event that the Executive becomes disabled during his employment hereunder through any illness, injury, accident or condition of either a physical
or psychological nature and, as a result, is unable to perform substantially all of his duties and responsibilities hereunder (notwithstanding the provision of any reasonable accommodation) for one hundred and eighty (180) days during any period of
three hundred and sixty-five (365) consecutive calendar days, whether or not consecutive. In the event of such termination, the Company shall have no further obligation or liability to the Executive, other than for payment of any Final
Compensation due the Executive. Other than business expenses described in Section 5(a)(iii), Final Compensation shall be paid to the Executive at the time prescribed by applicable law and in all events within thirty (30) days following the date
of termination of employment.
 (ii) The Board may designate another employee to act in the Executive’s place during any period of the
Executive’s disability. Notwithstanding any 

 
such designation, the Executive shall continue to receive the Base Salary in accordance with Section 4(a) and to participate in Employee Benefit Plans in accordance with Section 4(d), to the
extent permitted by the then-current terms of the applicable Employee Benefit Plans, until the Executive becomes eligible for disability income benefits under the Company’s disability income plan, if any, or until the termination of his
employment, whichever shall first occur. While receiving disability income payments under any Company’s disability income plan, the Executive shall not be entitled to receive any Base Salary under Section 4(a), but shall continue to
participate in the Employee Benefit Plans in accordance with Section 4(d) and to the extent permitted by and subject to the then-current terms of such plans, until the termination of his employment hereunder. 

(iii) If any question shall arise as to whether the Executive is disabled through any illness, injury, accident or condition of either a
physical or psychological nature so as to be unable to perform substantially all of his duties and responsibilities hereunder, the Executive may, and at the request of the Company shall, submit to a medical examination by a physician selected by the
Company to whom the Executive or his duly appointed guardian, if any, has no reasonable objection to determine whether the Executive is disabled, and such determination shall for the purposes of this Agreement be conclusive. If such question
shall arise and the Executive shall fail to submit to such medical examination, the Company’s determination of the issue shall be binding on the Executive. 

(c) By the Company for Cause. The Company may terminate the Executive’s employment hereunder for Cause at any time upon
notice to the Executive setting forth in reasonable detail the nature of such Cause. The following, as determined by the Board in its reasonable judgment, shall constitute Cause for termination: 

(i) The Executive’s willful failure to perform, or gross negligence in the performance of, the Executive’s material duties and
responsibilities to the Company or any of its Affiliates that, if capable of cure, is not cured within thirty (30) days of written notice of such failure or negligence by the Company to the Executive; provided, that the Company will not have to
provide more than one notice and opportunity to cure with respect to any multiple, repeated, related or substantially similar events or circumstances; 

(ii) Conduct by the Executive that constitutes fraud, embezzlement or other material dishonesty with respect to the Company or any of its
Affiliates; 
 (iii) The Executive’s commission of, or plea of nolo contendere to, (A) a felony or (B) other crime involving moral
turpitude; or 
 (iv) The Executive’s material breach of this Agreement, any shareholder or option agreement between the Executive and
the Company or any of its Affiliates or of any fiduciary duty that the Executive has to the Company or any of its 

 
Affiliates that, if capable of cure, is not cured within thirty (30) days of written notice of such breach by the Company to the Executive; provided, that the Company will not have to provide
more than one notice and opportunity to cure with respect to any multiple, repeated, related or substantially similar events or circumstances.
 Upon the
giving of notice of termination of the Executive’s employment hereunder for Cause, the Company shall have no further obligation or liability to the Executive, other than for any Final Compensation due to the Executive. Other than business
expenses described in Section 5(a)(iii), Final Compensation shall be paid to the Executive at the time prescribed by applicable law and in all events within thirty (30) days following the date of termination of employment. 

(d) By the Company Other Than for Cause. The Company may terminate the Executive’s employment hereunder other than for Cause
at any time upon notice to the Executive. In the event of such termination, in addition to any Final Compensation due to the Executive, the Executive will be entitled to the following (the “Severance Benefits”): 

(i) the Company will pay the Executive severance pay, at the same rate as the Base Salary, for twelve (12) months following the date of
termination of his employment (the “Severance Period”); 
 (ii) during the Severance Period, provided the Executive elects
and remains eligible for COBRA (or mini-COBRA), the Company will pay the Executive a monthly taxable amount equal to the portion of the Executive’s health insurance premiums that the Company paid immediately prior to the date of termination
(the “Monthly Contribution”); and 
 (iii) if such termination occurs concurrent with or within twelve (12) months
following, or in connection with but within the three (3) months prior to, a Change of Control, the Company will pay the Executive an amount equal to his then current Target Bonus, payable in substantially equal monthly installments during the
Severance Period. 
 Other than business expenses described in Section 5(a)(iii), Final Compensation shall be paid to the Executive at the time prescribed
by applicable law and in all events within thirty (30) days following the date of termination of employment. Any obligation of the Company to provide the Severance Benefits is conditioned, however, on the Executive signing and returning to the
Company (without revoking) a timely and effective general release of claims in the form (which shall be provided by the Company within seven (7) days following the date of termination, which shall exclude nonwaivable claims and the Executive’s
rights to Final Compensation and which shall not require the Executive to agree to post-employment obligations not specifically set forth in this Agreement) by the deadline specified therein, all of which (including the lapse of the period for
revoking the release of claims as specified in the release of claims) shall have occurred no later than 

 
the sixtieth (60th) calendar day following the date of termination (any such separation agreement submitted by such deadline, the “Release of Claims”) and on the
Executive’s continued compliance in material respects with the obligations of the Executive to the Company and its Affiliates that survive termination of his employment, including without limitation under Sections 7, 8 and 9 of this
Agreement. Subject to Section 5(g) below, all Severance Benefits to which the Executive is entitled hereunder shall be payable in accordance with the normal payroll practices of the Company, with the first payment, which shall be retroactive to
the day immediately following the date the Executive’s employment terminated, being due and payable on the Company’s next regular payday for executives that follows the effective date of the Release of Claims. Notwithstanding the
foregoing, if the time period to consider, return and revoke the Release of Claims covers two of the Executive’s taxable years, any portion of the Severance Benefits that constitutes deferred compensation subject to Section 409A (as defined
below) shall in all events be paid in the later taxable year. The Release of Claims required for Severance Benefits in accordance with this Section 5(d) creates legally binding obligations on the part of the Executive and the Company therefore
advises the Executive to seek the advice of an attorney before signing the Release of Claims. 
 (e) By the Executive for Good
Reason. The Executive may terminate his employment hereunder for Good Reason by (A) providing notice to the Company specifying in reasonable detail the condition giving rise to the Good Reason no later than the thirtieth (30th) day following the
occurrence of that condition; (B) providing the Company a period of thirty (30) days to remedy the condition and so specifying in the notice and (C) terminating his employment for Good Reason within thirty (30) days following the expiration of the
period to remedy if the Company fails to remedy the condition. The following, if occurring without the Executive’s consent, shall constitute “Good Reason” for termination by the Executive: 

(i) a material diminution in the nature or scope of the Executive’s title, duties, authority or responsibilities;

(ii) a requirement that the Executive relocate his principal work location to a location more than thirty (30) miles outside of Boston, MA;
or 
 (iii) a material reduction in Base Salary. 

In the event of a termination of employment in accordance with this Section 5(e), the Executive will be entitled to receive the Severance Benefits he
would have been entitled to receive had he been terminated by the Company other than for Cause pursuant to Section 5(d) above, provided that the Executive signs and returns (without revoking) a timely and effective Release of Claims as set forth in
Section 5(d). 
 (f) By the Executive. The Executive may terminate his employment hereunder at any time upon thirty (30) days’
prior written notice to the Company. In the event of termination of the Executive’s employment in accordance with this Section 5(e), 

 
the Board may elect to waive the period of notice, or any portion thereof, and, if the Board so elects, the Company will pay the Executive the Base Salary for the period so waived. The
Company shall also pay the Executive any Final Compensation due him (other than business expenses described in Section 5(a)(iii)) at the time prescribed by applicable law and in all events within thirty (30) days following the date of the
termination of employment. 
 (g) Timing of Payments and Section 409A. 

(i) Notwithstanding anything to the contrary in this Agreement, if at the time of the Executive’s termination of employment, the
Executive is a “specified employee,” as defined below, any and all amounts payable under this Section 5 on account of such separation from service that constitute deferred compensation and would (but for this provision) be payable
within six (6) months following the date of termination, shall instead be paid on the next business day following the expiration of such six (6) month period or, if earlier, upon the Executive’s death; except (A) to the extent of amounts that
do not constitute a deferral of compensation within the meaning of Treasury regulation Section 1.409A-1(b) (including without limitation by reason of the safe harbor set forth in Section 1.409A-1(b)(9)(iii), as determined by the Company in its
reasonable good faith discretion); (B) benefits that qualify as excepted welfare benefits pursuant to Treasury regulation Section 1.409A-1(a)(5); or (C) other amounts or benefits that are not subject to the requirements of Section 409A of the Code
(“Section 409A”).
 (ii) For purposes of this Agreement, all references to “termination of employment” and
correlative phrases shall be construed to require a “separation from service” (as defined in Section 1.409A-1(h) of the Treasury regulations after giving effect to the presumptions contained therein), and the term “specified
employee” means an individual determined by the Company to be a specified employee under Treasury regulation Section 1.409A-1(i).

(iii) Each payment made under this Agreement shall be treated as a separate payment and the right to a series of installment payments under
this Agreement is to be treated as a right to a series of separate payments. 
 (iv) Any payment of or reimbursement for expenses that
would constitute nonqualified deferred compensation subject to Section 409A shall be subject to the following additional rules: (i) no reimbursement or payment of any such expense shall affect the Executive’s right to reimbursement or payment
of any such expense in any other calendar year; (ii) reimbursement or payment of the expense shall be made, if at all, promptly, but not later than the end of the calendar year following the calendar year in which the expense was incurred; and (iii)
the right to reimbursement or payment shall not be subject to liquidation or exchange for any other benefit. 

 (v) In no event shall the Company have any liability relating to the failure or alleged failure
of any payment or benefit under this Agreement to comply with, or be exempt from, the requirements of Section 409A. 
 (h) Exclusive
Right to Severance. The Executive agrees that the Severance Benefits to be provided to him in accordance with the terms and conditions set forth in this Agreement are intended to be exclusive with respect to severance or termination pay and
post-employment employee benefits. The Executive hereby knowingly and voluntarily waives any right he might otherwise have to participate in or receive benefits under any other plan, program or policy of the Company providing for severance or
termination pay or benefits. 
 6. Effect of Termination. The provisions of this Section 6 shall apply to any termination
of the Executive’s employment under this Agreement, whether pursuant to Section 5 or otherwise. 
 (a) Provision by the Company
of Final Compensation and Severance Benefits, if any, that are due the Executive in each case under the applicable termination provision of Section 5 shall constitute the entire obligation of the Company to the Executive with respect to severance or
termination pay and post-employment employee benefits.
 (b) Except for any right of the Executive to continue group health plan
participation in accordance with applicable law, the Executive’s participation in all Employee Benefit Plans shall terminate pursuant to the terms of the applicable plan documents based on the date of termination of the Executive’s
employment without regard to any Base Salary for notice waived pursuant to Section 5(e) hereof or to any Severance Benefits or other payment made to or on behalf of the Executive following such date of termination.

(c) Provisions of this Agreement shall survive any termination of the Executive’s employment if so provided herein or if necessary or
desirable fully to accomplish the purposes of other surviving provisions, including without limitation the obligations of the Executive under Sections 7, 8 and 9. The obligation of the Company to provide Severance Benefits hereunder, and
Executive’s right to retain such payments, is expressly conditioned on the Executive’s continued compliance in all material respects with Sections 7, 8 and 9. The Executive recognizes that, except as expressly provided in
Section 5(d) or Section 5(e), or with respect to Base Salary paid for notice waived pursuant to Section 5(e), no cash compensation or benefits will be earned after termination of employment. 

7. Confidential Information.

 (a) The Executive acknowledges that the Company and its Affiliates continually develop
Confidential Information, that the Executive will develop Confidential Information for the Company or its Affiliates and that the Executive will learn of Confidential Information during the course of employment. The Executive agrees that all
Confidential Information which the Executive creates or to which he has access as a result of his employment or other associations with the Company or any of its Affiliates is and shall remain the sole and exclusive property of the Company or its
Affiliate, as applicable. The Executive shall comply with the policies and procedures of the Company and its Affiliates for protecting Confidential Information and shall never disclose to any Person (except as required by applicable law or for
the proper performance of his duties and responsibilities to the Company and its Affiliates), or use for his own benefit or gain or the benefit or gain of any other Person, any Confidential Information obtained by the Executive incident to his
employment or any other association with the Company or any of its Affiliates. The Executive understands that this restriction shall continue to apply after his employment terminates, regardless of the reason for such termination. Further,
the Executive agrees to furnish prompt notice to the Company of any required disclosure of Confidential Information sought pursuant to subpoena, court order or any other legal process or requirement, and agrees to provide the Company a reasonable
opportunity to seek protection of the Confidential Information prior to any such disclosure. The confidentiality obligation under this Section 7 shall not apply to information that has become generally known through no wrongful act on the part
of the Executive or any other Person having an obligation of confidentiality to the Company or any of its Affiliates. Nothing in this Agreement limits, restricts or in any other way affects the Executive from communicating with any governmental
agency or entity, or communicating with any official or staff person of a governmental agency or entity, concerning matters relevant to the governmental agency or entity. 

(b) All documents, records, tapes and other media of every kind and description relating to the business, present or otherwise, of the
Company or any of its Affiliates and any copies or derivatives (including without limitation electronic), in whole or in part, thereof (the “Documents”), whether or not prepared by the Executive, shall be the sole and exclusive
property of the Company and its Affiliates. Except in the proper performance of the Executive’s regular duties for the Company or as expressly authorized in writing in advance by the Board or its expressly authorized designee, the
Executive will not copy any Documents or remove any Documents or copies or derivatives thereof from the premises of the Company. The Executive shall safeguard all Documents and shall surrender to the Company at the time his employment
terminates, and at such earlier time or times as the Board or its designee may specify, all Documents and other property of the Company or any of its Affiliates and all documents, records and files of the customers and other Persons with whom the
Company or any of its Affiliates does business (“Third Party Documents”) and each individually a “Third Party Document”) then in the Executive’s possession or control; provided, however, that if a Document or
Third-Party Document is on electronic media, the Executive may, in lieu of surrendering 

 
the Document or Third-Party Document, provide a copy to the Company on electronic media and delete and overwrite all other electronic media copies thereof. The Executive also agrees that,
upon request of any duly authorized officer of the Company, the Executive shall disclose all passwords and passcodes necessary or desirable to enable the Company or any of its Affiliates or the Persons with whom the Company or any of its Affiliates
do business to obtain access to the Documents and Third-Party Documents. 
 8. Assignment of Rights to Intellectual
Property. The Executive shall promptly and fully disclose all Intellectual Property to the Company. The Executive hereby assigns and agrees to assign to the Company (or as otherwise directed by the Company) the Executive’s full
right, title and interest in and to all Intellectual Property. The Executive agrees to execute any and all applications for domestic and foreign patents, copyrights or other proprietary rights and to do such other acts (including without
limitation the execution and delivery of instruments of further assurance or confirmation) requested by the Company to assign the Intellectual Property to the Company (or as otherwise directed by the Company) and to permit the Company to enforce any
patents, copyrights or other proprietary rights to the Intellectual Property. The Executive will not charge the Company for time spent in complying with these obligations. All copyrightable works that the Executive creates shall be
considered “work made for hire” and shall, upon creation, be owned exclusively by the Company. 
 9. Restricted
Activities. The Executive agrees that the following restrictions on his activities during and after his employment are necessary to protect the goodwill, Confidential Information and other legitimate interests of the Company and its
Affiliates: 
 (a) While the Executive is employed by the Company and during the twelve (12) month period following the date his employment
terminates (or, in the case of a termination of employment by the Executive pursuant to Section 5(e), during the twelve (12) month period following the date, no more than thirty (30) days prior to the date of termination, when the Executive provides
written notice of termination to the Company), regardless of the reason therefore (in the aggregate, the “Restricted Period”), the Executive shall not, directly or indirectly, whether as owner, partner, investor, consultant, agent,
employee, co-venturer or otherwise, engage in any Competitive Business Activities in any geographic area in which the Company or any of its Affiliates engages in any business activity or is actively planning to engage in any business activity at any
time during the Executive’s employment with the Company or, with respect to the portion of the Restricted Period that follows termination of the Executive’s employment, at the time of such termination (the “Restricted
Area”). Specifically, but without limiting the foregoing, the Executive agrees not to work or provide services, in any capacity in the Restricted Area, whether as an employee, independent contractor or otherwise, whether with or
without compensation, to any Person who is engaged in the business of developing, marketing or selling (i) therapeutic drugs to treat liver disease or

 
constipation or (ii) any other drug that has a therapeutic purpose that is the same or substantially similar to the therapeutic purpose of any drug that the Company or any of its Affiliates is
developing, marketing or selling during the Executive’s employment with the Company or, with respect to the portion of the Restricted Period that follows termination of the Executive’s employment, at the time of such termination
(“Competitive Business Activities”). Nothing in this Section 9(a), however, shall prevent the Executive’s passive ownership of two (2) percent or less of the equity securities of any publicly traded company. 

(b) The Executive agrees that, during his employment with the Company, he will not undertake any outside activity, whether or not competitive
with the business of the Company or its Affiliates that could reasonably give rise to a conflict of interest or otherwise interfere with any of his duties or obligations to the Company or any of its Affiliates.

(c) The Executive agrees that, during the Restricted Period, he will not directly or indirectly: (i) solicit or encourage any customer or
business partner of the Company or any of its Affiliates to terminate or diminish its relationship with them; or (ii) seek to persuade any such customer or business partner or any prospective customer or business partner of the Company or any
of its Affiliates to conduct with anyone else any business or activity which such customer or business partner conducts, or such prospective customer or business partner could conduct, with the Company or any of its Affiliates; provided,
however, that these restrictions shall apply (A) only with respect to those Persons who are or have been a customer or business partner of the Company or any of its Affiliates at any time within the immediately preceding two (2)-year period or whose
business has been solicited on behalf of the Company or any of the Affiliates by any of their officers, employees or agents within such two (2)-year period, other than by form letter, blanket mailing or published advertisement, and (B) only if the
Executive has performed work for such Person during his employment with the Company or one of its Affiliates or been introduced to, or otherwise had contact with, such Person as a result of his employment or other associations with the Company
or one of its Affiliates or has had access to Confidential Information which would assist in the Executive’s solicitation of such Person. 

(d) The Executive agrees that, during the Restricted Period (excluding any activities undertaken on behalf of the Company or any of its
Affiliates in the course of his duties hereunder), the Executive will not, and will not assist any other Person to, (i) hire, engage or solicit for hiring or engagement any employee of the Company or any of its Affiliates or seek to persuade any
employee of the Company or any of its Affiliates to discontinue employment or (ii) solicit or encourage any independent contractor providing services to the Company or any of its Affiliates to terminate or diminish its relationship with them;
provided, however, that these restrictions shall apply only to employees and independent contractors who have provided services to the Company or any of its Affiliates at any time within the immediately preceding two-(2) year period. 

 10. Enforcement of Covenants. The Executive acknowledges that he has carefully read
and considered all the terms and conditions of this Agreement, including the restraints imposed upon him pursuant to Sections 7, 8 and 9. The Executive agrees without reservation that each of the restraints contained herein is necessary
for the reasonable and proper protection of the goodwill, Confidential Information and other legitimate interests of the Company and its Affiliates; that each and every one of these restraints is reasonable in respect to subject matter, length of
time and geographic area; and that these restraints, individually or in the aggregate, will not prevent him from obtaining other suitable employment during the period in which the Executive is bound by them. The Executive further agrees that he
will never assert, or permit to be asserted on his behalf, in any forum, any position contrary to the foregoing. The Executive further acknowledges that, were he to breach any of the covenants contained in Sections 7, 8 or 9, the damage to
the Company and its Affiliates would be irreparable. The Executive therefore agrees that the Company, in addition to any other remedies available to it, shall be entitled to preliminary and permanent injunctive relief against any breach or
threatened breach by the Executive of any of said covenants, without having to post bond, and will additionally be entitled to an award of attorney’s fees incurred in connection with securing any relief hereunder. The parties further agree
that, in the event that any provision of Section 7, 8 or 9 shall be determined by any court of competent jurisdiction to be unenforceable by reason of its being extended over too great a time, too large a geographic area or too great a range of
activities, such provision shall be deemed to be modified to permit its enforcement to the maximum extent permitted by law. The Executive agrees that the Restricted Period shall be tolled, and shall not run, during any period of time in which
he is in violation of the terms thereof, in order that the Company and its Affiliates shall have all of the agreed-upon temporal protection recited herein. No breach of any provision of this Agreement by the Company, or any other claimed breach
of contract or violation of law, or change in the nature or scope of the Executive’s employment relationship with the Company, shall operate to extinguish the Executive’s obligation to comply with Sections 7, 8 and 9. Each of the
Company’s Affiliates shall have the right to enforce all of the Executive’s obligations to that Affiliate under this Agreement, including without limitation pursuant to Section 7, 8 or 9. 

11. No Conflicting Agreements. The Executive hereby represents and warrants that the execution of this Agreement and the
performance of his obligations hereunder will not breach or be in conflict with any other agreement to which the Executive is a party or is bound and that the Executive is not now subject to any covenants against competition or similar covenants or
any other obligations to any Person or to any court order, judgment or decree that would affect the performance of his obligations hereunder. The Executive will not disclose to or use on behalf of the Company any proprietary information of a
third party without such party’s consent. 

 12. Definitions. Capitalized words or phrases shall have the meanings provided in
this Section 12 and as provided elsewhere herein: 
 (a) “Affiliate” means any person or entity directly or indirectly
controlling, controlled by or under common control with the Company, where control may be by either management authority or equity interest. 

(b) “Code” means the Internal Revenue Code of 1986, as amended. 

(c) “Change of Control” has the meaning ascribed to such term in the Rules of the Albireo Limited Share Option Plan to be
adopted in 2016, as may be amended from time to time, which meaning is incorporated herein by reference as if restated in its entirety. 

(d) “Confidential Information” means any and all information of the Company and its Affiliates that is not generally
available to the public, and any and all information, publicly known in whole or in part or not, which, if disclosed by the Company or any of its Affiliates, would assist in competition against any of them. Confidential Information includes
without limitation such information relating to (i) the development, research, testing, manufacturing, marketing and financial activities of the Company and its Affiliates, (ii) the Products, (iii) the costs, sources of supply, financial
performance and strategic plans of the Company and its Affiliates, (iv) the identity and special needs of the patients of the Company and its Affiliates and (v) the people and organizations with whom the Company and its Affiliates have
business relationships and the nature and substance of those relationships. Confidential Information also includes information that the Company or any of its Affiliates has received, or may receive hereafter, belonging to others or that was
received by the Company or any of its Affiliates with any understanding, express or implied, that it would not be disclosed. 
 (e)
“Intellectual Property” means inventions, discoveries, developments, methods, processes, compositions, works, concepts and ideas (whether or not patentable or copyrightable or constituting trade secrets) conceived, made, created,
developed or reduced to practice by the Executive (whether alone or with others, whether or not during normal business hours or on or off Company premises) during the Executive’s employment and during the period of six (6) months immediately
following termination of his employment that relate either to the Services or to any prospective activity of the Company or any of its Affiliates or that result from any work performed by the Executive for the Company or any of its Affiliates or
that make use of Confidential Information or any of the equipment or facilities of the Company or any of its Affiliates.
 (f)
“Person” means a natural person, a corporation, a limited liability company, an association, a partnership, an estate, a trust and any other entity or organization, other than the Company or any of its Affiliates. 

 (g) “Products” means all products planned, researched, developed, tested, sold,
licensed, leased, or otherwise distributed or put into use by the Company or any of its Affiliates, together with all services provided or otherwise planned by the Company or any of its Affiliates, during the Executive’s employment. 

13. Withholding. All payments made by the Company under this Agreement shall be reduced by any tax or other amounts required to be
withheld by the Company under applicable law. 
 14. Section 280G.

(a) In the event that the Company or Parent undergoes a “change in ownership or control” (within the meaning of Section 280G of the
Code and the regulations and guidance promulgated thereunder (“Section 280G”)) before the Company or Parent or any Affiliate of the Company or Parent that would be treated, together with the Company or Parent, as a single
corporation under Section 280G has stock that is readily tradeable on an established securities market or otherwise (within the meaning of Section 280G) and all, or any portion, of the payments provided under this Agreement, either alone or together
with other payments or benefits which the Executive receives or is entitled to receive from the Company or Parent (collectively, the “Total Payments”), could constitute an “excess parachute payment” within the meaning of
Code Section 280G, the Company will use its reasonable best efforts to seek shareholder approval of the Total Payments in a manner that satisfies the requirements of the “shareholder approval” exception to Section 280G, such that, if
approved, all Total Payments may be made to the Executive without the application of the excise tax imposed by Section 4999 of the Code. 

(b) In the event that the Company or Parent undergoes a “change in ownership or control” (within the meaning of Section 280G)
before the Company or Parent or any Affiliate of the Company or Parent that would be treated, together with the Company or Parent, as a single corporation under Section 280G has stock that is readily tradeable on an established securities market or
otherwise (within the meaning of Section 280G) and all, or any portion, of the Total Payments could constitute an “excess parachute payment” within the meaning of Section 280G, then the Executive shall be entitled to receive (i) an amount
limited (to the minimum extent necessary) so that no portion of the Total Payments shall be non-deductible for US federal income taxes by reason of Section 280G (the “Limited Amount”), or (ii) if the amount of the Total Payments
(without regard to clause (i)) reduced by the excise tax imposed by Section 4999 of the Code (the “Excise Tax”) and the amount of all other applicable federal, state and local taxes (with income taxes all computed at the highest
applicable marginal rate) is greater than the Limited Amount reduced by the amount of all taxes applicable thereto 

 
(with income taxes all computed at the highest marginal rate), the amount of the Total Payments otherwise payable without regard to clause (i). If it is determined that the Limited Amount will
maximize the Employee’s after-tax proceeds, the Total Payments shall be reduced to equal the Limited Amount in the following order: (i) first, by reducing cash severance payments that are exempt from Section 409A, (ii) second, by reducing other
payments and benefits that are exempt from Section 409A and to which Q&A 24(c) of Section 1.280G-1 of the Treasury Regulations does not apply, (iii) third, by reducing all remaining payments and benefits that are exempt from Section 409A and
(iv) finally, by reducing payments and benefits that are subject to Section 409A, in each case, with all such reductions done on a pro rata basis. All determinations made pursuant this Section 14 will be made at the Company’s or its
Affiliates’ expense by an accounting firm or consulting group with experience in performing calculations regarding the applicability of Section 280G and Section 4999 of the Code selected by the Company for such purpose (the “Independent
Advisors”). For purposes of such determinations, no portion of the Total Payments shall be taken into account which, in the opinion of the Company and its legal advisors, (y) does not constitute a “parachute payment” within
the meaning of Section 280G(b)(2) of the Code (including by reason of Section 280G(b)(4)(A) of the Code) or (z) constitutes reasonable compensation for services actually rendered, within the meaning of Section 280G(b)(4)(B) of the Code, in excess of
the “base amount” (as defined in Section 280G(b)(3) of the Code) allocable to such reasonable compensation. In the event it is later determined that (A) a greater reduction in the Total Payments should have been made to implement
the objective and intent of this Section 14, the excess amount shall be returned immediately by the Executive to the Company or (B) a lesser reduction in the Total Payments should have been made to implement the objective and intent of this
Section 14, the additional amount shall be paid immediately by Parent, the Company, or any Affiliate of Parent or the Company, as applicable, to the Executive.

15. Assignment. Neither the Company nor the Executive may make any assignment of this Agreement or any interest herein, by
operation of law or otherwise, without the prior written consent of the other; provided, however, that the Company may assign its rights and obligations under this Agreement without the consent of the Executive to one of its Affiliates or in the
event that the Company shall hereafter effect a reorganization with, consolidate with, or merge into, an Affiliate or any Person or transfer all or substantially all of its properties, stock, or assets to an Affiliate or any Person. This
Agreement shall inure to the benefit of and be binding upon the Company and the Executive, and their respective successors, executors, administrators, heirs and permitted assigns. 

16. Severability. If any portion or provision of this Agreement shall to any extent be declared illegal or unenforceable by a
court of competent jurisdiction, then the remainder of this Agreement, or the application of such portion or provision in circumstances other than those as to which it is so declared illegal or unenforceable, shall not be affected thereby, and each
portion and provision of this Agreement shall be valid and enforceable to the fullest extent permitted by law. 

 17. Waiver. No waiver of any provision hereof shall be effective unless made in
writing and signed by the waiving party. The failure of either party to require the performance of any term or obligation of this Agreement, or the waiver by either party of any breach of this Agreement, shall not prevent any subsequent
enforcement of such term or obligation or be deemed a waiver of any subsequent breach. 
 18. Notices. Any and all notices,
requests, demands and other communications provided for by this Agreement shall be in writing and shall be effective when delivered in person, consigned to a reputable national courier service or deposited in the United States mail, postage prepaid,
registered or certified, and addressed to the Executive at his last known address on the books of the Company or, in the case of the Company, at its principal place of business, attention of the CEO, or to such other address as either party may
specify by notice to the other actually received. 
 19. Entire Agreement. This Agreement constitutes the entire agreement
between the parties and supersedes and terminates all prior communications, agreements and understandings, written or oral, with respect to the terms and conditions of the Executive’s employment relationship with the Company. 

20. Amendment. This Agreement may be amended or modified only by a written instrument signed by the Executive and by an expressly
authorized representative of the Company. 
 21. Headings. The headings and captions in this Agreement are for convenience only
and in no way define or describe the scope or content of any provision of this Agreement. 
 22. Counterparts. This Agreement
may be executed in two or more counterparts, each of which shall be an original and all of which together shall constitute one and the same instrument. 

23. Governing Law. This is a Massachusetts contract and shall be construed and enforced under and be governed in all respects by
the laws of Massachusetts, without regard to any conflict of laws principles that would result in the application of the laws of any other jurisdiction.

 24. Guaranty. 

(a) Guaranty. As a material inducement to the Executive to enter into this Agreement, each of Parent and Albireo AB does hereby
unconditionally, absolutely and irrevocably guarantee the payment of all compensation, payments, awards and other amounts that the Company is obligated to pay or provide the Executive pursuant to this Agreement (together, the
“Guaranty”). Such compensation, payments, awards, obligations are hereinafter referred to as the “Payment Obligations.” If the Company does not timely pay all or any part of the Payment Obligations due
under this Agreement to the Executive when they become due and payable, following notice to the Company and a reasonable opportunity of not less than thirty (30) days to cure, the Executive may immediately enforce the Guaranty against either or both
of Parent and Albireo AB for the Payment Obligations, without any obligation to first pursue payment of some or all of the Payment Obligations from the Company. 

(b) Nature, Scope and Duration of Guaranty. The Guaranty shall be directly enforceable against either or both of Parent and
Albireo AB and without resorting to the Company, or exhausting any or all remedies against them. Neither Parent nor Albireo AB shall be discharged or released from liability for any of the following reasons: bankruptcy, receivership or other
similar proceedings. The Guaranty shall be binding upon Parent, Albireo AB, and their respective successors and assigns, and shall inure to the benefit of the Executive and his heirs and assigns. No assignment or delegation by Parent or
Albireo AB shall release Parent or Albireo AB of its obligations under this Section 24. The Guaranty shall be a continuing guaranty and shall remain in force until the termination of this Agreement and payment in full of the Payment
Obligations. 
 (c) Waiver. The failure of the Executive to enforce any of the provisions of this
Section 24 at any time, or for any period of time, shall not be construed to be a waiver of any such provision or of the right thereafter to enforce the same. 

(d) Survival. This Section 24, including without limitation the rights of the Executive and obligations of Parent and Albireo AB
under this Section 24, shall survive the end of the term of this Agreement and the termination of the Executive’s employment with the Company. 

(e) Jurisdiction. Each of Parent and Albireo AB hereby consents to personal jurisdiction of the state and federal
courts situated within Suffolk County, Massachusetts solely for purposes of enforcing this Section 24, and waives any objections that it might have to personal jurisdiction or venue in those courts for purposes of enforcing this Section 24. 

 [The remainder of this page has been left blank intentionally.] 

 IN WITNESS WHEREOF, this Agreement has been executed as a sealed instrument by the Company, by
its duly authorized representative, and by the Executive, as of the date first above written. 
  

					
	THE EXECUTIVE:	 		 	THE COMPANY:
			
	/s/ Peter A. Zorn            	 		 	By:  /s/ Ron Cooper                  
		 		 	Name:  Ron Cooper                  
		 		 	Title:  President & CEO            

 IN WITNESS WHEREOF, Parent and Albireo AB execute this Agreement, solely with respect to Section 24, effective
as of the Effective Date. 
  

					
	Albireo Limited	 		 	Albireo AB
			
	By: /s/ Ron Cooper                    	 		 	By: /s/ Jan Mattsson                      
	Name:  Ron Cooper                  	 		 	Name:  Jan Mattsson                      
	Title:    President & CEO          	 		 	Title:    COOEX-10.8

 Exhibit 10.8 

FORM OF INDEMNIFICATION AGREEMENT 

THIS INDEMNIFICATION AGREEMENT (this “Agreement”) is made and entered into this
     day of                     , 2016, by and between Albireo Pharma, Inc., a Delaware corporation (the
“Company”), and              (“Indemnitee”). 

WHEREAS, qualified persons are reluctant to serve corporations as directors, officers or otherwise unless they are provided
with broad indemnification and insurance against claims arising out of their service to and activities on behalf of the corporations; and 

WHEREAS, the Company has determined that attracting and retaining such persons is in the best interests of the Company’s
stockholders and that it is reasonable, prudent and necessary for the Company to indemnify such persons to the fullest extent permitted by applicable law and to provide reasonable assurance regarding insurance; 

NOW, THEREFORE, the Company and Indemnitee hereby agree as follows: 

1. Defined Terms; Construction. 

(a) Defined Terms. As used in this Agreement, the following terms shall have the following meanings: 

“Change in Control” means, and shall be deemed to have occurred if, on or after the date of this Agreement, (i) any
“person” (as such term is used in Sections 13(d) and 14(d) of the Securities Exchange Act of 1934, as amended), other than (A) a trustee or other fiduciary holding securities under an employee benefit plan of the Company or any Company
Subsidiary acting in such capacity, or (B) a corporation owned directly or indirectly by the stockholders of the Company in substantially the same proportions as their ownership of stock of the Company, is or becomes the “beneficial owner”
(as defined in Rule 13d-3 under said Act), directly or indirectly, of securities of the Company representing more than 20% of the total voting power represented by the Company’s then outstanding Voting Securities, (ii) during any period of two
consecutive years, individuals who at the beginning of such period constitute the board of directors of the Company and any new director whose election by the board of directors of the Company or nomination for election by the Company’s
stockholders was approved by a vote of at least two-thirds (2/3) of the directors then still in office who either were directors at the beginning of the period or whose election or nomination for election was previously so approved, cease for any
reason to constitute a majority thereof, (iii) the stockholders of the Company approve a merger or consolidation of the Company with any other corporation other than a merger or consolidation that would result in the Voting Securities of the Company
outstanding immediately prior thereto continuing to represent (either by remaining outstanding or by being converted into Voting Securities of the surviving entity) at least 80% of the total voting power represented by the Voting Securities of the
Company or such surviving entity outstanding immediately after such merger or consolidation, (iv) the stockholders of the Company approve a plan of complete liquidation of the Company or an agreement for the sale or disposition by the Company of (in
one transaction or a series of related transactions) all or substantially all of its assets, or (v) the Company shall file or have filed against it, and such filing shall not be dismissed, any bankruptcy, insolvency or dissolution proceedings, or a
trustee, administrator or creditors committee shall be appointed to manage or supervise the affairs of the Company. 

 “Company Subsidiary” means any direct or indirect subsidiary of the Company from
time to time. 
 “Corporate Status” means the status of a person who is or was a director (or a member of any committee of
a board of directors), officer, employee or agent (including without limitation a manager of a limited liability company) of the Company or any Company Subsidiary, or of any predecessor thereof, or is or was serving at the request of the Company as
a director (or a member of any committee of a board of directors), officer, employee or agent (including without limitation a manager of a limited liability company) of another entity, or of any predecessor thereof, including service with respect to
an employee benefit plan. 
 “Determination” means a determination that either (x) there is a reasonable basis for
the conclusion that indemnification of Indemnitee is proper in the circumstances because Indemnitee met a particular standard of conduct (a “Favorable Determination”) or (y) there is no reasonable basis for the conclusion
that indemnification of Indemnitee is proper in the circumstances because Indemnitee met a particular standard of conduct (an “Adverse Determination”). An Adverse Determination shall include the decision that a Determination
was required in connection with indemnification and the decision as to the applicable standard of conduct. 
 “DGCL” means
the General Corporation Law of the State of Delaware, as amended from time to time. 
 “Expenses” means all (i)
attorneys’ fees and expenses, retainers, court, arbitration and mediation costs, transcript costs, fees and expenses of experts, witness and public relations consultants bonds and fees, traveling expenses, costs of collecting and producing
documents, travel expenses, duplicating costs, printing and binding costs, telephone charges, postage, delivery service fees and all other disbursements or expenses of the types customarily incurred in connection with prosecuting, defending,
preparing to prosecute or defend, investigating, being or preparing to be a witness in, appealing or otherwise participating in a Proceeding or responding to, or objecting to, a request to provide discovery in any Proceeding, (ii) damages,
judgments, fines and amounts paid in settlement and any other amounts that Indemnitee becomes legally obligated to pay (including any federal, state or local taxes imposed on Indemnitee as a result of receipt of reimbursements or advances of
expenses under this Agreement) and (iii) the premium, security for, and other costs relating to any costs bond, supersedes bond or other appeal bond or its equivalent, whether civil, criminal, arbitrational, administrative or investigative with
respect to any Proceeding actually and reasonably incurred by Indemnitee, or on Indemnitee’s behalf, because of any claim or claims made against or by him in connection with any Proceeding, whether formal or informal (including an action by or
in the right of the Company), to which Indemnitee is, was or at any time becomes a party or a witness, or is threatened to be made a party to, participant in or a witness with respect to, by reason of Indemnitee’s Corporate Status. 

“Independent Legal Counsel” means an attorney or firm of attorneys competent to render an opinion under the applicable law,
selected in accordance with the provisions of Section 5(e), who has not performed any services (other than services similar to those contemplated to be performed by Independent Legal Counsel under this Agreement) for the Company or any Company
Subsidiary or for Indemnitee within the last three years. 
 “Proceeding” means a threatened, pending or completed action,
suit or proceeding, whether civil, criminal, administrative or investigative, including without limitation a claim, demand, discovery request, formal or informal investigation, inquiry, administrative hearing, arbitration or other form of
alternative dispute resolution, including an appeal from any of the foregoing. 

  
 2 

 “Voting Securities” means any securities of the Company that vote generally in
the election of directors. 
 (b) Construction. For purposes of this Agreement, 

(i) References to the Company or to a Company Subsidiary shall include any corporation, limited liability company, partnership,
joint venture, trust or other entity or enterprise that before or after the date of this Agreement is party to a merger or consolidation with the Company or such Company Subsidiary or that is a successor to the Company as contemplated by Section
8(e) (whether or not such successor has executed and delivered the written agreement contemplated by Section 8(e)). 
 (ii)
References to “fines” shall include any excise taxes assessed on Indemnitee with respect to an employee benefit plan. 

(iii) References to a “witness” in connection with a Proceeding shall include any interviewee or person called upon
to produce documents in connection with such Proceeding. 
 2. Agreement to Serve. 

Indemnitee agrees to serve as a director or officer of the Company or one or more Company Subsidiaries and in such other capacities as
Indemnitee may serve at the request of the Company from time to time. By its execution of this Agreement the Company confirms its request that Indemnitee serve as a director or officer and in such other capacities. Indemnitee shall be entitled to
resign or otherwise terminate such service with immediate effect at any time, and neither such resignation or termination nor the length of such service shall affect Indemnitee’s rights under this Agreement. This Agreement shall not
constitute an employment agreement, supersede any employment agreement to which Indemnitee is a party or create any right of Indemnitee to continued employment or appointment. 

3. Indemnification. 
 (a)
General Indemnification. The Company shall indemnify Indemnitee, to the fullest extent permitted by applicable law in effect on the date hereof or as amended to increase the scope of permitted indemnification, against Expenses, losses,
liabilities, judgments, fines, penalties and amounts paid in settlement (including all interest, taxes, assessments and other charges in connection therewith) incurred by Indemnitee or on Indemnitee’s behalf in connection with any Proceeding in
any way connected with, resulting from or relating to Indemnitee’s Corporate Status. 
 (b) Additional Indemnification Regarding
Expenses. Without limiting the foregoing, in the event any Proceeding is initiated by Indemnitee, the Company or any other person to enforce or interpret this Agreement or any rights of Indemnitee to indemnification or advancement of
Expenses (or related obligations of Indemnitee) under the Company’s or any applicable Company Subsidiary’s certificate of incorporation, bylaws or other organizational agreement or instrument, any other agreement to which Indemnitee and
the Company or any Company Subsidiary are party, any 

  
 3 

 
vote of stockholders or directors of the Company or any Company Subsidiary, the DGCL, any other applicable law or any liability insurance policy, the Company shall indemnify Indemnitee against
Expenses incurred by Indemnitee or on Indemnitee’s behalf in connection with such Proceeding in proportion to the success achieved by Indemnitee in such Proceeding and the efforts required to obtain such success, as determined by the court
presiding over such Proceeding. 
 (c) Partial Indemnification. If Indemnitee is entitled under any provision of this Agreement
to indemnification by the Company for a portion of any Expenses, losses, liabilities, judgments, fines, penalties and amounts paid in settlement incurred by Indemnitee, but not for the total amount thereof, the Company shall nevertheless indemnify
Indemnitee for such portion. 
 (d) Nonexclusivity. The indemnification provided by this Agreement shall not be deemed exclusive
of any rights to which Indemnitee may be entitled under the certificate of incorporation, bylaws or other organizational agreement or instrument of the Company or any Company Subsidiary, any other agreement, any vote of stockholders or directors,
the DGCL, any other applicable law or any liability insurance policy. 
 (e) Exceptions. Any other provision herein to the
contrary notwithstanding, the Company shall not be obligated under the Agreement to indemnify Indemnitee: 
 (i) For Expenses
incurred in connection with Proceedings initiated or brought voluntarily by the Indemnitee and not by way of defense, counterclaim or crossclaim, except (x) as contemplated by Section 3(b), (y) in specific cases if the board of
directors of the Company has approved the initiation or bringing of such Proceeding, and (z) as may be required by law. 

(ii) For an accounting of profits arising from the purchase and sale by the Indemnitee of securities within the meaning of
Section 16(b) of the Securities Exchange Act of 1934, as amended, or any similar provisions of any federal, state or local law if the final, non-appealable judgment of a court of competent jurisdiction finds Indemnitee to be liable for disgorgement
under such Section 16(b). 
 (iii) On account of Indemnitee’s conduct that is established by a final, non-appealable
judgment of a court of competent jurisdiction as knowingly fraudulent or deliberately dishonest or that constituted willful misconduct. 

(iv) For which payment is actually made to Indemnitee under a valid and collectible insurance policy or under a valid and
enforceable indemnity clause, bylaw or agreement, except in respect of any excess beyond payment actually received by Indemnitee under such insurance, clause, bylaw or agreement. 

(v) if and to the extent indemnification is prohibited by applicable law. 

(f) Subrogation. In the event of payment under this Agreement, the Company shall be subrogated to the extent of such payment to
all of the rights of recovery of the Indemnitee, who shall execute such documents and do such acts as the Company may reasonably request to secure such rights and to enable the Company effectively to bring suit to enforce such rights. 

  
 4 

 4. Advancement of Expenses. 

The Company shall pay all Expenses incurred by Indemnitee in connection with any Proceeding in any way connected with, resulting from or
relating to Indemnitee’s Corporate Status, other than a Proceeding initiated by Indemnitee for which the Company would not be obligated to indemnify Indemnitee pursuant to Section 3(e)(i), in advance of the final disposition (in accordance with
Section 5(c)) of such Proceeding and without regard to whether Indemnitee will ultimately be entitled to be indemnified for such Expenses and without regard to whether an Adverse Determination has been made, except as contemplated by the last
sentence of Section 5(f). The right to advances under this Section 4 shall in all events continue until final disposition of any Proceeding, including any appeal therein. Advances shall be made without regard to Indemnitee’s ability to
repay the expenses and without regard to Indemnitee’s ultimate entitlement to indemnification under the other provisions of this Agreement. Indemnitee shall qualify for advances upon the execution and delivery to the Company of this Agreement
and Indemnitee shall repay such amounts advanced only if and to the extent that it shall ultimately be determined in a decision by a court of competent jurisdiction from which no appeal can be taken that Indemnitee is not entitled to be indemnified
by the Company for such Expenses. The right to advancement described in this Section 4 is vested. Such repayment obligation shall be unsecured and shall not bear interest. The Company shall not impose on Indemnitee additional
conditions to advancement or require from Indemnitee additional undertakings regarding repayment. 
 5. Indemnification Procedure.

 (a) Notice of Proceeding; Cooperation. Indemnitee shall give the Company notice in writing as soon as practicable, and, in
any event, no later than 30 days after Indemnitee becomes aware, of any Proceeding for which indemnification will or could be sought under this Agreement; provided that any failure or delay in giving such notice shall not relieve the Company of its
obligations under this Agreement unless and to the extent that (i) neither the Company nor any Company Subsidiary is party to or aware of such Proceeding and (ii) the Company is materially prejudiced by such failure. 

(b) Settlement. The Company will not, without the prior written consent of Indemnitee, which may be provided or withheld in
Indemnitee’s sole discretion, effect any settlement of any Proceeding against Indemnitee or which could have been brought against Indemnitee unless such settlement solely involves the payment of money by persons other than Indemnitee and
includes an unconditional release of Indemnitee from all liability on any matters that are the subject of such Proceeding and an acknowledgment that Indemnitee denies all wrongdoing in connection with such matters. The Company shall not be
obligated to indemnify Indemnitee against amounts paid in settlement of a Proceeding against Indemnitee if such settlement is effected by Indemnitee without the Company’s prior written consent, which shall not be unreasonably withheld. 

(c) Request for Payment; Timing of Payment. To obtain indemnification payments or advances under this Agreement, Indemnitee shall
submit to a Company a written request therefor, together with such invoices or other supporting information as may be reasonably requested by the Company and reasonably available to Indemnitee. The Company shall make indemnification payments to
Indemnitee no later than 30 days, and advances to Indemnitee no later than 20 days, after receipt of the written request of Indemnitee. 

  
 5 

 (d) Determination. The Company intends that Indemnitee shall be indemnified to the fullest
extent permitted by law as provided in Section 3 and that no Determination shall be required in connection with such indemnification. In no event shall a Determination be required in connection with advancement of Expenses pursuant to Section 4
or in connection with indemnification for Expenses incurred as a witness or incurred in connection with any Proceeding or portion thereof with respect to which Indemnitee has been successful on the merits or otherwise. Any decision that a
Determination is required by law in connection with any other indemnification of Indemnitee, and any such Determination, shall be made within 30 days after receipt of Indemnitee’s written request for indemnification, as follows: 

(i) If no Change in Control has occurred, (w) by a majority vote of the directors of the Company who are not parties to
such Proceeding, even though less than a quorum, with the advice of Independent Legal Counsel, or (x) by a committee of such directors designated by majority vote of such directors, even though less than a quorum, with the advice of
Independent Legal Counsel, or (y) if there are no such directors, or if such directors so direct, by Independent Legal Counsel in a written opinion to the Company and Indemnitee, or (z) by the stockholders of the Company. 

(ii) If a Change in Control has occurred, by Independent Legal Counsel in a written opinion to the Company and Indemnitee. 

The Company shall pay all Expenses incurred by Indemnitee in connection with a Determination. 

(e) Independent Legal Counsel. If there has not been a Change in Control, Independent Legal Counsel shall be selected by the board
of directors of the Company and approved by Indemnitee (which approval shall not be unreasonably withheld or delayed). If there has been a Change in Control, Independent Legal Counsel shall be selected by Indemnitee and approved by the Company
(which approval shall not be unreasonably withheld or delayed). The Company shall pay the fees and expenses of Independent Legal Counsel and indemnify Independent Legal Counsel against any and all expenses (including attorneys’ fees),
claims, liabilities and damages arising out of or relating to its engagement. 
 (f) Consequences of Determination; Remedies of
Indemnitee. The Company shall be bound by and shall have no right to challenge a Favorable Determination. If an Adverse Determination is made, or if for any other reason the Company does not make timely indemnification payments or
advances of Expenses, Indemnitee shall have the right to commence a Proceeding before a court of competent jurisdiction to challenge such Adverse Determination and/or to require the Company to make such payments or advances. Indemnitee shall be
entitled to be indemnified for all Expenses incurred in connection with such a Proceeding in accordance with Section 3(b) and to have such Expenses advanced by the Company in accordance with Section 4. If Indemnitee fails to timely challenge an
Adverse Determination, or if Indemnitee challenges an Adverse Determination and such Adverse Determination has been upheld by a final judgment of a court of competent jurisdiction from which no appeal can be taken, then, to the extent and only to
the extent required by such Adverse Determination or final judgment, the Company shall not be obligated to indemnify or advance Expenses to Indemnitee under this Agreement. 

  
 6 

 (g) Presumptions; Burden and Standard of Proof. In connection with any Determination,
or any review of any Determination, by any person, including a court: 
 (i) It shall be a presumption that a Determination
is not required. 
 (ii) It shall be a presumption that Indemnitee has met the applicable standard of conduct and that
indemnification of Indemnitee is proper in the circumstances. 
 (iii) The burden of proof shall be on the Company to
overcome the presumptions set forth in the preceding clauses (i) and (ii), and each such presumption shall only be overcome if the Company establishes that there is no reasonable basis to support it. 

(iv) The termination of any Proceeding by judgment, order, finding, settlement (whether with or without court approval) or
conviction, or upon a plea of nolo contendere, or its equivalent, shall not create a presumption that indemnification is not proper or that Indemnitee did not meet the applicable standard of conduct or that a court has determined that
indemnification is not permitted by this Agreement or otherwise. 
 (v) Neither the failure of any person or persons to have
made a Determination nor an Adverse Determination by any person or persons shall be a defense to Indemnitee’s claim or create a presumption that Indemnitee did not meet the applicable standard of conduct, and any Proceeding commenced by
Indemnitee pursuant to Section 5(f) shall be de novo with respect to all determinations of fact and law. 
 6. Directors and
Officers Liability Insurance. 
 (a) Maintenance of Insurance. So long as the Company maintains liability insurance for any
directors, officers, employees or agents of the Company, the Company shall ensure that Indemnitee is covered by such insurance in such a manner as to provide Indemnitee the same rights and benefits as are accorded to the most favorably insured of
the Company’s then current directors and officers. If at any date (i) such insurance ceases to cover acts and omissions occurring during all or any part of the period of Indemnitee’s Corporate Status or (ii) the Company does not maintain
any such insurance, the Company shall ensure that Indemnitee is covered, with respect to acts and omissions prior to such date, for at least six years (or such shorter period as is available on commercially reasonable terms) from such date, by other
directors and officers liability insurance, in amounts and on terms (including the portion of the period of Indemnitee’s Corporate Status covered) no less favorable to Indemnitee than the amounts and terms of the liability insurance maintained
by the Company on the date hereof. 
 (b) Notice to Insurers. Upon receipt of notice of a Proceeding pursuant to Section 5(a),
the Company shall give or cause to be given prompt notice of such Proceeding to all insurers providing liability insurance in accordance with the procedures set forth in all applicable or potentially applicable policies. The Company shall
thereafter take all necessary action to cause such insurers to pay all amounts payable in accordance with the terms of such policies. 
 7.
Exculpation, etc. 
 (a) Limitation of Liability. If Indemnitee is a director of the Company or any Company Subsidiary,
Indemnitee shall not be personally liable to the Company or such Company Subsidiary or to the stockholders of the Company or such Company Subsidiary for monetary damages for breach of fiduciary duty as a director of the Company or such Company
Subsidiary; provided, however, that the foregoing shall not eliminate or limit the liability of the Indemnitee (i) 

  
 7 

 
for any breach of the Indemnitee’s duty of loyalty to the Company or such Company Subsidiary or the stockholders thereof; (ii) for acts or omissions not in good faith or which involve
intentional misconduct or a knowing violation of the law; (iii) under Section 174 of the DGCL or any similar provision of other applicable corporations law; or (iv) for any transaction from which the Indemnitee derived an improper personal
benefit. If the DGCL or such other applicable law shall be amended to permit further elimination or limitation of the personal liability of directors, then the liability of the Indemnitee shall, automatically, without any further action, be
eliminated or limited to the fullest extent permitted by the DGCL or such other applicable law as so amended. 
 (b) Period of
Limitations. No legal action shall be brought and no cause of action shall be asserted by or in the right of the Company or any Company Subsidiary against Indemnitee or Indemnitee’s estate, spouses, heirs, executors, personal or legal
representatives, administrators or assigns after the expiration of two years from the date of accrual of such cause of action, and any claim or cause of action of the Company shall be extinguished and deemed released unless asserted by the timely
filing of a legal action within such two-year period; provided that, if any shorter period of limitations is otherwise applicable to any such cause of action, such shorter period shall govern. 

8. Miscellaneous. 
 (a)
Non-Circumvention. The Company shall not seek or agree to any order of any court or other governmental authority that would prohibit or otherwise interfere, and shall not take or fail to take any other action if such action or failure
would reasonably be expected to have the effect of prohibiting or otherwise interfering, with the performance of the Company’s indemnification, advancement or other obligations under this Agreement. 

(b) Severability. If any provision or provisions of this Agreement shall be held to be invalid, illegal or unenforceable for any
reason whatsoever: (i) the validity, legality and enforceability of the remaining provisions of this Agreement (including without limitation, each portion of any section of this Agreement containing any such provision held to be invalid,
illegal or unenforceable, that is not itself invalid, illegal or unenforceable) shall not in any way be affected or impaired thereby and shall remain enforceable to the fullest extent permitted by law; (ii) such provision or provisions shall be
deemed reformed to the extent necessary to conform to applicable law and to give the maximum effect to the intent of the parties hereto; and (iii) to the fullest extent possible, the provisions of this Agreement (including, without limitation, each
portion of any section of this Agreement containing any such provision held to be invalid, illegal or unenforceable, that is not itself invalid, illegal or unenforceable) shall be construed so as to give effect to the intent manifested thereby. 

(c) Notices. All notices, requests, demands and other communications under this Agreement shall be in writing and shall be deemed duly
given (i) on the date of delivery if delivered personally, or by facsimile, upon confirmation of receipt, (ii) on the first business day following the date of dispatch if delivered by a recognized next-day courier service or (iii) on the third
business day following the date of mailing if delivered by domestic registered or certified mail, properly addressed, or on the fifth business day following the date of mailing if sent by airmail from a country outside of North America, to
Indemnitee at the address shown on the signature page of this Agreement, to the Company at the address shown on the signature page of this Agreement, or in either case as subsequently modified by written notice. 

  
 8 

 (d) Amendment and Termination. No amendment, modification, termination or
cancellation of this Agreement shall be effective unless it is in writing signed by all the parties hereto. No waiver of any of the provisions of this Agreement shall be deemed or shall constitute a waiver of any other provisions hereof
(whether or not similar), nor shall such waiver constitute a continuing waiver. 
 (e) Successors and Assigns. This Agreement
shall be binding upon the Company and its respective successors and assigns, including without limitation any acquiror of all or substantially all of the Company’s assets or business, any person (as such term is used in Sections 13(d) and 14(d)
of the Securities Exchange Act of 1934, as amended) that acquires beneficial ownership of securities of the Company representing more than 20% of the total voting power represented by the Company’s then outstanding Voting Securities and any
survivor of any merger or consolidation to which the Company is party, and shall inure to the benefit of and be enforceable by Indemnitee and Indemnitee’s estate, spouses, heirs, executors, personal or legal representatives, administrators and
assigns. The Company shall require and cause any such successor, by written agreement in form and substance satisfactory to Indemnitee, expressly to assume and agree to perform this Agreement as if it were named as the Company herein, and the
Company shall not permit any such purchase of assets or business, acquisition of securities or merger or consolidation to occur until such written agreement has been executed and delivered. No such assumption and agreement shall relieve the
Company of any of its obligations hereunder, and this Agreement shall not otherwise be assignable by the Company. This Agreement is personal in nature and neither of the parties hereto shall, without the consent of the other, assign or delegate this
Agreement or any rights or obligations. Without limiting the generality or effect of the foregoing, Indemnitee’s right to receive payments hereunder shall not be assignable, whether by pledge, creation of a security interest or otherwise,
other than by a transfer by the Indemnitee’s will or by estate law, and, in the event of any attempted assignment or transfer contrary to this Section 8(e), the Company shall have no liability to pay any amount so attempted to be assigned or
transferred. 
 (f) Choice of Law; Consent to Jurisdiction. This Agreement shall be governed by and its provisions construed in
accordance with the laws of the State of Delaware, as applied to contracts between Delaware residents entered into and to be performed entirely within Delaware, without regard to the conflict of law principles thereof. The Company and
Indemnitee each hereby irrevocably consents to the jurisdiction of the courts of the State of Delaware for all purposes in connection with any Proceeding which arises out of or relates to this Agreement and agree that any action instituted under
this Agreement shall be brought only in the state courts of the State of Delaware. 
 (g) Integration and Entire Agreement. This
Agreement sets forth the entire understanding between the parties hereto and supersedes and merges all previous written and oral negotiations, commitments, understandings and agreements relating to the subject matter hereof between the parties
hereto, provided that the provisions hereof shall not supersede the provisions of the Company’s certificate of incorporation, bylaws or other organizational agreement or instrument, any other agreement, any vote of stockholders or directors,
the DGCL or other applicable law, to the extent any such provisions shall be more favorable to Indemnitee than the provisions hereof. 
 (h)
Counterparts. This Agreement may be executed in two counterparts, each of which shall constitute an original. 

  
 9 

 IN WITNESS WHEREOF, the parties hereto have executed
this Agreement as of the date first above written. 
  

			
	ALBIREO PHARMA, INC.
		
	By:	 	 

 
			
	 Name:
	 	
	 Title:
	 	

 
			
		
	Address:	 	 
		 	 
		 	 

  

			
	AGREED TO AND ACCEPTED:
		
	INDEMNITEE:	 	

			
		
	 	 	 

			
	 Name:
	 	

			
		
	Address:	 	 
		 	 
		 	 

  
 10

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