Document:

Exhibit 10.10

 

	 	 

                                                                     9 Bond Court
 Leeds
 LS1 2JZ

	 	 
	 	Tel: 0113 895 0130
	 	 
	 	www.4Dpharmaplc.com

 

	Private & Confidential

Dr Sandy Macrae

1241 Shrader Street

San Francisco

CA 94117

USA	
        

         

         

         

         

        

        

 

19 August 2019

 

Dear Sandy

 

Letter of appointment

 

The board of directors (Board)
of 4D pharma plc (Company) has appointed you as non-executive director. This letter sets out the terms of your appointment.
If you are unhappy with any of the terms, or need any more information, please let me know.

 

By accepting this appointment,
you agree that this letter is a contract for services and is not a contract of employment and you confirm that you are not subject
to any restrictions which prevent you from holding office as a director of the Company.

 

		1.	Appointment

 

		1.1	Subject to the remaining provisions of this letter, your
appointment shall continue unless terminated by either party giving to the other three months’ prior written notice.

 

		1.2	Your appointment is subject to the Company’s articles
of association, as amended from time to time (Articles). Nothing in this letter shall be taken to exclude or vary the terms
of the Articles as they apply to you as a director of the Company. You are required to retire and seek re-election by the shareholders
at the Company’s annual general meeting (AGM) as required by the Articles. The Articles require any director appointed
by the board to retire and seek re-election at the next AGM; and then generally one third of the directors to retire by rotation
and seek re-election at each AGM.

 

Registered Office: 4D pharma plc 9 Bond Court Leeds LS1 2JZ United Kingdom

 Registered In England and Wales, Company Number 08840579

 

     

     

    

 

		1.3	Continuation of your appointment is contingent on your
continued satisfactory performance and re-election by the shareholders and any relevant statutory provisions relating to removal
of a director. If the shareholders do not re-elect you as a director, or you are retired from office under the Articles, your
appointment shall terminate automatically, with immediate effect and without compensation beyond termination.

 

		1.4	You may be required to serve on one or more Board committees.
You will be provided with the relevant terms of reference on your appointment to such a committee.

 

		1.5	Notwithstanding paragraph 1.1 to paragraph 1.4, the Company
may terminate your appointment with immediate effect if you have:

 

		1.5.1	committed a material breach of your obligations under
this letter;

 

		1.5.2	committed any serious or repeated breach or non-observance
of your obligations to the Company (which include an obligation not to breach   your statutory, fiduciary or common-law
duties);

 

		1.5.3	been guilty of any fraud or dishonesty or acted in any
manner which, in the Company’s opinion, brings or is likely to bring you or the  Company into disrepute or is materially
adverse to the Company’s interests;

 

		1.5.4	been convicted of an arrestable criminal offence other
than a road traffic offence for which a fine or non-custodial penalty is imposed;

 

		1.5.5	been declared bankrupt or have made an arrangement with
or for the benefit of your creditors; or

 

		1.5.6	been disqualified from acting as a director.

 

		1.6	On termination of your appointment, you shall, at the Company’s request, resign from your
office as director of the Company and any offices you hold in any of the Company’s group companies.

 

		1.7	If matters arise which cause you concern about your role, you should discuss these matters with
the chairman. If you have any concerns which cannot be resolved, and you choose to resign for that, or any other, reason, you should
provide an appropriate written statement to the chairman for circulation to the Board.

 

		2.	Time Commitment

 

		2.1	You will be expected to devote such time as is necessary for the proper performance of your duties.
This will include attendance at bimonthly Board meetings and the AGM, meetings with the non-executive directors, meetings with
shareholders and meetings forming part of the Board evaluation process and updating and training meetings. In addition, you will
be required to consider all relevant papers before each meeting. Unless urgent and unavoidable circumstances prevent you from doing
so, it is expected that you will attend the meetings outlined in this paragraph.

 

    -2-

     

    

 

		2.2	The nature of the role makes it impossible to be specific about the maximum time commitment. You
may be required to devote additional time to the Company in respect of preparation time and ad hoc matters which may arise and
particularly when the Company is undergoing a period of increased activity. At certain times it may be necessary to convene additional
Board, committee or shareholder meetings.

 

		2.3	By accepting this appointment, you confirm that, taking into account all of your other commitments,
you are able to allocate sufficient time to the Company to discharge your responsibilities effectively.

 

3.              
Role and Duties

 

		3.1	The Board as a whole is collectively responsible for the success of the Company. The Board’s
role is to:

 

		3.1.1	provide entrepreneurial leadership of the Company within
a framework of prudent and effective controls which enable risk to be assessed and managed;

 

		3.1.2	set the Company’s strategic aims, ensure that the
necessary financial and human resources are in place for the Company to meet its objectives, and review management performance;
and

 

		3.1.3	set the Company’s values and standards and ensure
that its obligations to its shareholders and others are understood and met.

 

		3.2	As a non-executive director you shall have the same general
legal responsibilities to the Company as any other director. You are expected to perform your duties (whether statutory, fiduciary
or common law) faithfully, diligently and to a standard commensurate with the functions of your role and your knowledge, skills
and experience.

 

		3.3	You shall exercise your powers in your role as a non-executive
director having regard to relevant obligations under prevailing law and regulation, including the Companies Act 2006 and the Rules
for Companies relating to the AIM market operated by the London Stock Exchange.

 

		3.4	You shall have particular regard to the general duties
of directors in Part 10, Chapter 2 of the Companies Act 2006, including the duty to promote the success of the Company under which
all directors must act in the way they consider, in good faith, would be most likely to promote the success of the Company for
the benefit of its members as a whole. In doing so, as a director, you must have regard (among other matters) to:

 

3.4.1         
the likely consequences of any decision in the long term;

 

3.4.2         
the interests of the Company’s employees;

 

3.4.3         
the need to foster the Company’s business relationships with suppliers, customers and others;

 

3.4.4         
the impact of the Company’s operations on the community and the environment;

 

    -3-

     

    

 

3.4.5         
 the desirability of the Company maintaining a reputation for high standards of business conduct; and

 

3.4.6         
the need to act fairly as between the members of the Company.

 

3.5           
In your role as a non-executive director, you shall also be required to:

 

		3.5.1	constructively challenge and help develop proposals on
strategy;

 

		3.5.2	scrutinise the performance of management in meeting agreed
goals and objectives and monitor the reporting of performance;

 

		3.5.3	satisfy yourself on the integrity of financial information
and that financial controls and systems of risk management are robust and defensible;

 

		3.5.4	be responsible for determining appropriate levels of
remuneration of executive directors and have a prime role in appointing and, where necessary, removing senior management and in
succession planning;

 

		3.5.5	devote time to developing and refreshing your knowledge
and skills;

 

		3.5.6	uphold high standards of integrity and probity and support
the executive directors in instilling the appropriate culture, values and behaviours in the boardroom and beyond;

 

		3.5.7	insist on receiving high-quality information sufficiently
in advance of Board meetings;

 

		3.5.8	take into account the views of shareholders and other
stakeholders where appropriate;

 

		3.5.9	make sufficient time available to discharge your responsibilities
effectively;

 

		3.5.10	exercise relevant powers under, and abide by, the Articles;

 

		3.5.11	 disclose
the nature and extent of any direct or indirect interest you may have in any matter being considered at a Board or committee meeting
and, except as permitted under the Articles you will not vote on any resolution of the Board, or of one of its committees, on
any matter where you have any direct or indirect interest;

 

		3.5.12	immediately report your own wrongdoing or the wrongdoing
or proposed wrongdoing of any employee or other director of the Company of which you become aware to the chairman;

 

		3.5.13	exercise your powers as a director in accordance with
the Company’s policies and procedures; and

 

		3.5.14	not do anything that would cause you to be disqualified
from acting as a director.

 

		3.6	Unless the Board specifically authorises you to do so,
you shall not enter into any legal or other commitment or contract on behalf of the Company.

 

		3.7	You shall be entitled to request all relevant information
about the Company’s affairs as is reasonably necessary to enable you to discharge your duties.

 

    -4-

     

    

 

		4.	Fees and Expenses

 

		4.1	You shall be paid an annual fee of £50,000 gross
(current at the date of this letter), which shall be paid in equal instalments monthly in arrear after deduction of any taxes
and other amounts that are required by law, which shall be subject to an annual review by the Board. This fee covers all duties,
including service on any Board committee.

 

		4.2	The Company shall reimburse you for all reasonable and
properly documented expenses that you incur in performing the duties of your office.

 

		4.3	On termination of your appointment, you shall only be
entitled to such fees as may have accrued to the date of termination, together with reimbursement in the normal way of any expenses
properly incurred before that date.

 

		5.	Independent Professional Advice

 

In some circumstances you may
consider that you need professional advice in the furtherance of your duties and it may be appropriate for you to seek advice from
independent advisers at the Company’s expense. A copy of the Board’s agreed procedure under which directors may obtain
such independent advice is available from the Board. The Company shall reimburse the reasonable cost of expenditure incurred by
you in accordance with its policy.

 

		6.	Outside Interests

 

		6.1	You have already disclosed to the Board the significant commitments you have outside your role
in the Company, including with respect to your role as President and Chief Executive Officer of, and as a member of the board of
directors of, Sangamo Therapeutics, Inc. You must inform the chairman in advance of any changes to these commitments.

 

		6.2	It is accepted and acknowledged that you have business interests other than those of the Company
and have declared any conflicts that are apparent to you at present. If you become aware of any further potential or actual conflicts
of interest, these should be disclosed to the chairman and company secretary as soon as you become aware of them.

 

		7.	Confidentiality

 

		7.1	You acknowledge that all information that should be reasonably understood by you to be confidential
or proprietary information of the Company and that is furnished or disclosed to you by the Company in the provision of your services
to the Company is confidential to the Company and should not be released, communicated or disclosed to third parties or used for
any reason other than in the interests of the Company, either during your appointment or following termination (by whatever means),
without prior clearance from the chairman. This restriction shall (a) not apply to any disclosure required by law or by the requirements
or regulations of any applicable regulatory authority, (b) cease to apply to any confidential information which may (other than
by reason of your breach) become available to the public generally and (c) otherwise cease to apply to you on the date that is
five (5) years following the termination of your service as a director of the Company. Notwithstanding the foregoing, it is understood
that this letter shall not prohibit or otherwise restrict you from using or disclosing information that was
either known to you prior to your appointment or that was independently learned by you outside of your relationship as a director
of the Company.

 

    -5-

     

    

 

		7.2	Nothing in this paragraph 7 shall prevent you from disclosing information which you are entitled
to disclose under the Public Interest Disclosure Act 1998, provided that the disclosure is made in accordance with the provisions
of that Act.

 

		8.	Inside Information and Dealing in the Company’s
Shares

 

		8.1	Your attention is drawn to the requirements under both law and regulation as to the disclosure
of inside information, in particular to the EU Market Abuse Regulation, the Disclosure and Transparency Rules of the UK Listing
Authority and section 52 of the Criminal Justice Act 1993 on insider dealing. You should avoid making any statements that might
risk a breach of these requirements. If in doubt, please contact the chairman or company secretary.

 

		8.2	During your period of appointment you are required to comply with the provisions of such code as
the Company may adopt from time to time which sets out the terms for dealings by directors in the Company’s publicly traded
or quoted securities. A copy of the current share dealing code adopted by the Company will be provided to you separately.

 

		9.	Training

 

On an ongoing basis, and further
to the annual evaluation process, the Company will arrange for you to develop and refresh your skills and knowledge in areas which
are mutually identified as being likely to be required, or of benefit to you, in carrying out your duties effectively. You should
try to make yourself available for any relevant training sessions which may be organised for the Board.

 

		10.	Review Process

 

The performance of individual
directors and the whole Board and its committees is evaluated annually. If, in the interim, there are any matters which cause you
concern about your role you should discuss them with the chairman as soon as you can.

 

		11.	Insurance and Indemnity

 

		11.1	The Company has directors’ and officers’
liability insurance with an indemnity limit of £5,000,000 and it intends to maintain such cover for the full term of your
appointment and for a period of not less than 6 years after it terminates. A copy of the policy document is available from the
Board.

 

		11.2	The Company shall grant you a deed of indemnity against
certain liabilities that may be incurred as a result of your office to the extent permitted by section 234 of the Companies Act
2006.

 

		12.	Changes to Personal Details

 

You shall advise the company
secretary promptly of any change in your address or other personal contact details.

 

    -6-

     

    

 

		13.	Return of Property

 

On termination of your appointment
with the Company however arising, or at any time at the Board’s request, you shall immediately return to the Company all
documents, records, papers or other property belonging to the Company or any company in the Company’s group which may be
in your possession or under your control, and which relate in any way to the Company’s or a group company’s business
affairs and you shall not retain any copies thereof.

 

		14.	Moral Rights

 

You hereby irrevocably waive
any moral rights in all works prepared by you, in the provision of your services to the Company, to which you are now or may at
any future time be entitled under Chapter IV of the Copyright Designs and Patents Act 1988 or any similar provisions of law in
any jurisdiction, including (but without limitation) the right to be identified, the right of integrity and the right against false
attribution, and agree not to institute, support, maintain or permit any action or claim to the effect that any treatment, exploitation
or use of such works or other materials, infringes your moral rights.

 

		15.	Data Protection

 

		15.1.1	By signing this letter you consent to the Company holding
and processing data about you for legal, personnel, administrative and management purposes including, as appropriate:

 

		15.1.2	information about your physical or mental health or condition
in order to monitor sick leave and take decisions as to your fitness to perform your duties; or

 

		15.1.3	your racial or ethnic origin or religious or similar
beliefs in order to monitor compliance with equal opportunities legislation; or

 

		15.2	information relating to any criminal proceedings in which
you have been involved for insurance purposes and in order to comply with legal requirements and obligations to third parties.

 

		15.3	You consent to the Company making such information available
to any of its group companies, those who provide products or services to the Company or any company in the Company’s group
(such as advisers and payroll administrators), regulatory authorities, potential or future employers, governmental or quasi-governmental
organisations and potential purchasers of the Company or the business in which you work.

 

		15.3	You also consent to the transfer of such information to the Company’s or any group company’s
business contacts outside the European Economic Area in order to further their business interests even where the country or territory
in question does not maintain adequate data protection standards.

 

    -7-

     

    

 

		16.	Third Party Rights

 

No one other than you and the
Company shall have any rights to enforce the terms of this letter.

 

		17.	Entire Agreement

 

		17.1	This letter and any document referred to in it constitutes
the entire terms and conditions of your appointment and supersedes and extinguishes all previous agreements, promises, assurances,
warranties, representations and understandings between you and the Company, whether written or oral, relating to its subject matter.

 

		17.2	17.2You agree that you shall have no remedies in
respect of any representation, assurance or warranty (whether made innocently or negligently) that is not set out in this letter
and you shall not have any claim for innocent or negligent misrepresentation based on any statement in this letter.

 

		18.	Variation

 

No variation of this letter shall
be effective unless it is in writing and signed by you and the Company (or respective authorised representatives).

 

		19.	Governing Law and Jurisdiction

 

Your appointment with the Company
and any dispute or claim arising out of or in connection with it or its subject matter or formation (including non-contractual
disputes or claims) shall be governed by and construed in accordance with the law of England and Wales and you and the Company
irrevocably agree that the courts of England and Wales shall have exclusive jurisdiction to settle any dispute or claim that arises
out of or in connection with this appointment or its subject matter or formation (including non-contractual disputes or claims).

 

Please indicate your acceptance of these
terms by signing and returning the attached copy of this letter.

 

Yours sincerely

 

Laurie Dale

Company Secretary

For and on behalf of 4D pharma plc

 

    -8-

     

    

 

I confirm and agree to the above terms
of my appointment as a non-executive director of 4D pharma plc as set out in this letter.

 

Signed on         August 2019 by Dr Sandy Macrae

 

    -9-Exhibit 10.11

 

 

	 	9 Bond Court
	 	Leeds
	 	LS1 2JZ
	 	 
	 	Tel: 0113 895 0130
	 	 
	 	www.4Dpharmaplc.com

 

Private & Confidential

Ed Baracchini, Ph.D., M.B.A.

322 Nautilus Street

La Jolla

CA 92037

USA

 

[06 December 2018]

 

Dear Ed

 

Letter of appointment

 

The board of directors (Board) of
4D pharma plc (Company) has appointed you as non-executive director. This letter sets out the main terms of your appointment.
If you are unhappy with any of the terms, or need any more information, please let me know.

 

By accepting this appointment, you agree
that this letter is a contract for services and is not a contract of employment and you confirm that you are not subject to any
restrictions which prevent you from holding office as a director.

 

		1	Appointment

 

		1.1	Subject to the remaining provisions of this letter, your appointment shall continue unless terminated
by either party giving to the other three months' prior written notice.

 

		1.2	Your appointment is subject to the Company's articles of association, as amended from time to time
(Articles). Nothing in this letter shall be taken to exclude or vary the terms of the Articles as they apply to you as a
director of the Company. You are required to retire and seek re-election by the shareholders at the Company's annual general meeting
(AGM) as required by the Articles. The Articles require any director appointed by the board to retire and seek re-election
at the next AGM; and then generally one third of the directors to retire by rotation and seek re-election at each AGM.

 

		1.3	Continuation of your appointment is contingent on your continued satisfactory performance and
                                                           re-election by the shareholders and any relevant statutory provisions relating to removal of a director. If the shareholders
                                                           do not re-elect you as a director, or you are retired from office under the Articles, your appointment shall terminate
                                                           automatically, with immediate effect and without compensation.

 

     

     

    

 

		1.4	You may be required to serve on one or more Board committees. You will be provided with the relevant
terms of reference on your appointment to such a committee.

 

		1.5	Notwithstanding paragraph 1.1 to paragraph 1.4, the Company may terminate your appointment with
immediate effect if you have-

 

		1.5.1	committed a material breach of your obligations under this letter;

 

		1.5.2	committed any serious or repeated breach or non-observance of your obligations to the Company (which
include an obligation not to breach your statutory, fiduciary or common-law duties);

 

		1.5.3	been guilty of any fraud or dishonesty or acted in any manner which, in the Company's opinion,
brings or is likely to bring you or the Company into disrepute or is materially adverse to the Company's interests;

 

		1.5.4	been convicted of an arrestable criminal offence other than a road traffic offence for which a
fine or non-custodial penalty is imposed;

 

		1.5.5	been declared bankrupt or have made an arrangement with or for the benefit of your creditors; or

 

		1.5.6	been disqualified from acting as a director.

 

		1.6	On termination of your appointment, you shall, at the Company's request, resign from your office
as director of the Company and any offices you hold in any of the Company's group companies.

 

		1.7	If matters arise which cause you concern about your role, you should discuss these matters with
the chairman If you have any concerns which cannot be resolved, and you choose to resign for that, or any other, reason, you should
provide an appropriate written statement to the chairman for circulation to the Board

 

		2	Time Commitment

 

		2.1	You will be expected to devote such time as is necessary for the proper performance of your duties
This will include attendance at bimonthly Board meetings and the AGM, meetings with the non-executive directors, meetings with
shareholders and meetings forming part of the Board evaluation process and updating and training meetings. In addition, you will
be required to consider all relevant papers before each meeting. Unless urgent and unavoidable circumstances prevent you from doing
so, it is expected that you will attend the meetings outlined in this paragraph.

 

		2.2	The nature of the role makes it impossible to be specific about the maximum time commitment. You
may be required to devote additional time to the Company in respect of preparation time and ad hoc matters which may arise and
particularly when the Company is undergoing a period of increased activity. At certain times it may be necessary to convene additional
Board, committee or shareholder meetings.

 

     

     

    

 

		2.3	By accepting this appointment, you confirm that, taking into account all of your other commitments,
you are able to allocate sufficient time to the Company to discharge your responsibilities effectively.

 

		3	Role and Duties

 

		3.1	The Board as a whole is collectively responsible for the success of the Company. The Board's role
is to:

 

		3.1.1	provide entrepreneurial leadership of the Company within a framework of prudent and effective controls
which enable risk to be assessed and managed;

 

		3.1.2	set the Company's strategic aims, ensure that the necessary financial and human resources are in
place for the Company to meet its objectives, and review management performance; and

 

		3.1.3	set the Company's values and standards and ensure that its obligations to its shareholders and
others are understood and met.

 

		3.2	As a non-executive director you shall have the same general legal responsibilities to the Company
as any other director. You are expected to perform your duties (whether statutory, fiduciary or common law) faithfully, diligently
and to a standard commensurate with the functions of your role and your knowledge, skills and experience.

 

		3.3	You shall exercise your powers in your role as a non-executive director having regard to relevant
obligations under prevailing law and regulation, including the Companies Act 2006 and the Rules for Companies relating to the AIM
market operated by the London Stock Exchange.

 

		3.4	You shall have particular regard to the general duties of directors in Part 10, Chapter 2 of the
Companies Act 2006, including the duty to promote the success of the Company under which all directors must act in the way they
consider, in good faith, would be most likely to promote the success of the Company for the benefit of its members as a whole.
In doing so, as a director, you must have regard (among other matters) to:

 

		3.4.1	the likely consequences of any decision in the long term;

 

		3.4.2	the interests of the Company's employees;

 

		3.4.3	the need to foster the Company's business relationships with suppliers, customers and others;

 

		3.4.4	the impact of the Company's operations on the community and the environment;

 

		3.4.5	the desirability of the Company maintaining a reputation for high standards of business conduct;
and

 

		3.4.6	the need to act fairly as between the members of the Company.

 

		3.5	In your role as a non-executive director, you shall also be required to:

 

		3.5.1	constructively challenge and help develop proposals on strategy;

 

     

     

    

 

		3.5.2	scrutinise the performance of management in meeting agreed goals and objectives and monitor the
reporting of performance;

 

		3.5.3	satisfy yourself on the integrity of financial information and that financial controls and systems
of risk management are robust and defensible;

 

		3.5.4	be responsible for determining appropriate levels of remuneration of executive directors and have
a prime role in appointing and, where necessary, removing senior management and in succession planning;

 

		3.5.5	devote time to developing and refreshing your knowledge and skills;

 

		3.5.6	uphold high standards of integrity and probity and support the executive directors in instilling
the appropriate culture, values and behaviours in the boardroom and beyond;

 

		3.5.7	insist on receiving high-quality information sufficiently in advance of Board meetings

 

		3.5.8	take into account the views of shareholders and other stakeholders where appropriate;

 

		3.5.9	make sufficient time available to discharge your responsibilities effectively;

 

		3.5.10	exercise relevant powers under, and abide by, the Articles;

 

		3.5.11	disclose the nature and extent of any direct or indirect interest you may have in any matter being
considered at a Board or committee meeting and, except as permitted under the Articles you will not vote on any resolution of the
Board, or of one of its committees, on any matter where you have any direct or indirect interest;

 

		3.5.12	immediately report your own wrongdoing or the wrongdoing or proposed wrongdoing of any employee
or other director of the Company of which you become aware to the chairman.

 

		3.5.13	exercise your powers as a director in accordance with the Company's policies and procedures; and

 

		3.5.14	not do anything that would cause you to be disqualified from acting as a director.

 

		3.6	Unless the Board specifically authorises you to do so, you shall not enter into any legal or other
commitment or contract on behalf of the Company.

 

		3.7	You shall be entitled to request all relevant information about the Company's affairs as is reasonably
necessary to enable you to discharge your duties.

 

		4	Fees and Expenses

 

		4.1	You shall be paid an annual fee of £50.000 gross (current at the date of this letter), which
shall be paid in equal instalments monthly in arrear after deduction of any taxes and other amounts that are required by law, which
shall be subject to an annual review by the Board. This fee covers all duties, including service on any Board committee.

 

     

     

    

 

		4.2	The Company shall reimburse you for all reasonable and properly documented expenses that you incur
in performing the duties of your office

 

		4.3	On termination of your appointment, you shall only be entitled to such fees as may have accrued
to the date of termination, together with reimbursement in the normal way of any expenses properly incurred before that date.

 

		5	Independent Professional Advice

 

In some circumstances you may
consider that you need professional advice in the furtherance of your duties and it may be appropriate for you to seek advice from
independent advisers at the Company's expense. A copy of the Board's agreed procedure under which directors may obtain such independent
advice is available from the Board. The Company shall reimburse the reasonable cost of expenditure incurred by you in accordance
with its policy.

 

		6	Outside Interests

 

		6.1	You have already disclosed to the Board the significant commitments you have outside your role
in the Company You must inform the chairman in advance of any changes to these commitments.

 

		6.2	It is accepted and acknowledged that you have business interests other than those of the Company
and have declared any conflicts that are apparent at present. If you become aware of any further potential or actual conflicts
of interest, these should be disclosed to the chairman and company secretary as soon as you become aware of them.

 

		7	Confidentiality

 

		7.1	You acknowledge that all information acquired during your appointment is confidential to the Company
and should not be released, communicated or disclosed to third parties or used for any reason other than in the interests of the
Company, either during your appointment or following termination (by whatever means), without prior clearance from the chairman
This restriction shall not apply to any disclosure required by law or by the requirements or regulations of any applicable regulatory
authority, and shall cease to apply to any confidential information which may (other than by reason of your breach) become available
to the public generally.

 

		7.2	Nothing in this paragraph 7 shall prevent you from disclosing information which you are entitled
to disclose under the Public Interest Disclosure Act 1998, provided that the disclosure is made in accordance with the provisions
of that Act.

 

		8	inside Information and Dealing In the Company's Shares

 

		8.1	Your attention is drawn to the requirements under both law and regulation as to the disclosure
of inside information, in particular to the EU Market Abuse Regulation, the Disclosure and Transparency Rules of the UK Listing
Authority and section 52 of the Criminal Justice Act 1993 on insider dealing. You should avoid making any statements that might
risk a breach of these requirements. If in doubt, please contact the chairman or company secretary.

 

		8.2	During your period of appointment you are required to comply with the provisions of such code as
the Company may adopt from time to time which sets out the terms for dealings by directors in theCompany's publicly traded or
quoted securities. A copy of the current share dealing code adopted by the Company will be provided to you separately

 

     

     

    

 

		9	Training

 

On an ongoing basis, and further
to the annual evaluation process, the Company will arrange for you to develop and refresh your skills and knowledge in areas which
are mutually identified as being likely to be required, or of benefit to you, in carrying out your duties effectively You should
try to make yourself available for any relevant training sessions which may be organised for the Board.

 

		10	Review Process

 

The performance of individual
directors and the whole Board and its committees is evaluated annually. If, in the interim, there are any matters which cause you
concern about your role you should discuss them with the chairman as soon as you can.

 

		11	Insurance and Indemnity

 

		11.1	The Company has directors' and officers' liability insurance and it intends to maintain such cover
for the full term of your appointment. A copy of the policy document is available from the Board.

 

		11.2	The Company shall grant you a deed of indemnity against certain liabilities that may be incurred
as a result of your office to the extent permitted by section 234 of the Companies Act 2006.

 

		12	Changes to Personal Details

 

You shall advise the company
secretary promptly of any change in your address or other personal contact details.

 

		13	Return of Property

 

On termination of your appointment
with the Company however arising, or at any time at the Board's request, you shall immediately return to the Company all documents,
records, papers or other property belonging to the Company or any company in the Company's group which may be in your possession
or under your control, and which relate in any way to the Company's or a group company's business affairs and you shall not retain
any copies thereof

 

		14	Moral Rights

 

You hereby irrevocably waive
any moral rights in all works prepared by you, in the provision of your services to the Company, to which you are now or may at
any future time be entitled under Chapter IV of the Copyright Designs and Patents Act 1988 or any similar provisions of law in
any jurisdiction, including (but without limitation) the right to be identified, the right of integrity and the right against false
attribution, and agree not to institute, support, maintain or permit any action or claim to the effect that any treatment, exploitation
or use of such works or other materials, infringes your moral rights.

 

		15	Data Protection

 

		15.1	By signing this letter you consent to the Company holding and processing data about you for legal,
personnel, administrative and management purposes including, as appropriate:

 

     

     

    

 

		15.1.1	information about your physical or mental health or condition in order to monitor sick leave and
take decisions as to your fitness to perform your duties; or

 

		15.1.2	your racial or ethnic origin or religious or similar beliefs in order to monitor compliance with
equal opportunities legislation; or

 

		15.1.3	information relating to any criminal proceedings in which you have been involved for insurance
purposes and in order to comply with legal requirements and obligations to third parties.

 

		15.2	You consent to the Company making such information available to any of its group companies, those
who provide products or services to the Company or any company in the Company's group (such as advisers and payroll administrators),
regulatory authorities, potential or future employers, governmental or quasi-governmental organisations and potential purchasers
of the Company or the business in which you work.

 

		15.3	You also consent to the transfer of such information to the Company's or any group company's business
contacts outside the European Economic Area in order to further their business interests even where the country or territory in
question does not maintain adequate data protection standards.

 

		16	Third Party Rights

 

No one other than you and the
Company shall have any rights to enforce the terms of this letter

 

		17	Entire Agreement

 

		17.1	This letter and any document referred to in it constitutes the entire terms and conditions of your
appointment and supersedes and extinguishes all previous agreements, promises, assurances, warranties, representations and understandings
between you and the Company, whether written or oral, relating to its subject matter.

 

		17.2	You agree that you shall have no remedies in respect of any representation, assurance or warranty
(whether made innocently or negligently) that is not set out in this letter and you shall not have any claim for innocent or negligent
misrepresentation based on any statement in this letter.

 

		18	Variation

 

No variation of this letter shall
be effective unless it is in writing and signed by you and the Company (or respective authorised representatives)

 

		19	Governing Law and Jurisdiction

 

Your appointment with the Company
and any dispute or claim arising out of or in connection with it or its subject matter or formation (including non-contractual
disputes or claims) shall be governed by and construed in accordance with the law of England and Wales and you and the Company
irrevocably agree that the courts of England and Wales shall have exclusive jurisdiction to settle any dispute or claim that arises
out of or in connection with this appointment or its subject matter or formation (including non-contractual disputes or claims).

 

Please indicate your acceptance of these
terms by signing and returning the attached copy of this letter

 

     

     

    

 

Yours sincerely

 

Laurie Dale

Company Secretary

For and on behalf of
4D pharma plc

 

I confirm and agree to the above terms
of my appointment as a non-executive director of 4D pharma plc as set out in this letter.

 

Signed on 9th December 2018
by Ed Baracchini

 

 

 

Registered Office. 4D pharma plc 9 Bond
Court Leeds LS1 2JZ United Kingdom

Registered In England and Wales, Company Number 08840579

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