Document:

EX-10.6.2

 Exhibit 10.6.2 

 
 

 
 TECHNOLOGY INCUBATION PROGRAM (TIP) 

5th AMENDED LEASE AGREEMENT 

This Lease is made and entered into by and between the UNIVERSITY OF CONNECTICUT (hereinafter “UNIVERSITY”), a constituent
unit of the State of Connecticut System of Higher Education, acting herein by its Vice President for Research pursuant to the provisions of Conn. Gen. Stat. § 4b-38, as revised, and Frequency Therapeutic, Inc., (hereinafter
“COMPANY”) organized and existing under the laws of the Commonwealth of Massachusetts and having its principal address of 300 Technology Square, 8th Floor, Cambridge, MA 01239, and
acting herein by David Lucchino, its Chief executive Officer, duly authorized. 
 WHEREAS, UNIVERSITY and COMPANY entered into a
Lease Agreement (as amended), last executed on September 7, 2018, whereby UNIVERSITY leased to COMPANY certain real property in connection with UNIVERSITY’s Technology Incubation Program (hereinafter, referred to as the “Existing
Lease”); 
 WHEREAS, as of the commencement of the Lease Term, as hereinafter defined, UNIVERSITY and COMPANY desire to
terminate the leasehold tenancy under the Existing Lease and replace and supersede the terms of the Existing Lease; 
 WHEREAS, as of
the commencement of the Lease Term, COMPANY desires to lease from the UNIVERSITY certain Demised Premises, as hereinafter defined, in accordance with the terms of this Lease; 

NOW THEREFORE, in consideration of the mutual exchange of promises contained herein, the parties agree as follows: 

1.    LEASE OF PREMISES: The UNIVERSITY hereby leases unto the COMPANY approximately 2,133 square feet of space,
comprising Room(s) R2804, R2805, R2809, R2810, R2812 and R2840, in the building known as the Cell & Genome Science Building (hereinafter the “Building”) located on the grounds of the University of Connecticut Health Center campus
at Farmington, Connecticut, together with the right of ingress into and egress out of the said premises and together with the improvements, fixtures, equipment and facilities of the UNIVERSITY now located or to be located on said premises
(hereinafter the “Demised Premises”). 
 2.    TERM OF LEASE: The term of the Lease shall extend from
August 1, 2019 and end on July 31, 2020 (hereinafter “Lease Term”). 
 3.    RENT: 

3.1    The COMPANY shall pay the UNIVERSITY rent on the 1st day of
each calendar month, in advance, during the term of this Lease, based on the following schedule and allowing for the stated increases each year: 
  

									
	 Lease Period
	  	Monthly Rent	 	  	Total Rent	 
	 8/1/2019 to 7/31/2020
	  	$	4,977.00	 	  	$	59,724.00	 
	 MAXIMUM TOTAL AMOUNT PAYABLE DURING THE LEASE TERM
	  
	  	$	59,724.00	 

  
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 3.2    The COMPANY shall pay rent by check, payable to the University of
Connecticut, and mailed to: 
 University of Connecticut 

Cash Operations 
 233 Glenbrook
Road, U-4231 
 Storrs, Connecticut 06269-4231. 

3.3    If the COMPANY fails to pay the rent within ten (10) days of first of each month, as stated in Section 3.1
herein, the COMPANY shall pay the UNIVERSITY a late payment charge of $50.00 per occurrence. The payment of this late charge is in addition to other remedies available to the UNIVERSITY under this Lease. 

4.    USE OF PREMISES: The Demised Premises shall be used only for the purpose of housing the
office and laboratory, to be used as a research and development facility of COMPANY and to promote the development of products and sales of COMPANY emanating from such research. COMPANY agrees that all activities conducted within the Demised
Premises shall be in full compliance with all federal and/or State rules and regulations, as well as any University of Connecticut written policies. University policies may be found online at http://www.policy.uconn.edu/ and
http://www.policies.uchc.edu/ and on the TIP website at http://www.tip.uconn.edu. 
 5.     UNIVERSITY’S
OBLIGATIONS: 
 5.1    The UNIVERSITY will provide and pay for: electricity; one telephone connection and one
data jack; heat; hot and cold running water and sewer systems; snow and ice removal; sanding; grounds keeping; janitorial service; parking in common with the other tenants of the Building under the prevailing terms and conditions for
UNIVERSITY’S employees; security; refuse removal from the Demised Premises; any renovations necessary to comply with any applicable fire, health, handicap accessibility and safety codes, including without limitation the American with
Disabilities Act (ADA); replacement of burnt-out bulbs, tubes and ballasts; toilet supplies; and structural maintenance and repairs. Extra outfitting or upgrades to the Facilities will be at the expense of the COMPANY. 

5.2    The UNIVERSITY, through the TIP, will provide to the COMPANY: access to the UNIVERSITY’S library and computer
network; hazardous waste removal information for the coordination of services, training, inspection and a sample chemical hygiene plan; business support services; conference rooms; cold room; and fax/copier. TIP may offer, under special arrangement
with the COMPANY: (1) access to specialized equipment and instrumentation; (2) connections to researchers and scientists; (3) animal facilities, as space allows and with appropriate faculty collaboration; and (4) access to the
Bioservices Center at Storrs and Core Facilities at the University of Connecticut Health Center. 
 5.3    The UNIVERSITY
will provide orientation to the COMPANY’S employees related to applicable UNIVERSITY policies. 
 6.    COMPANY
OBLIGATIONS: 
 6.1    Except as otherwise provided for in Section 5, COMPANY shall be responsible for the
following expenses, services and financial obligations related to use of the Demised Premises: payment of personal property taxes limited to COMPANY’S personal property and, in the case of real property taxes, a percentage of such taxes equal
to the percentage of square footage of the Demised Premises (prorated for partial years of occupancy); assessments, special assessments or special permits, or similar charges, if any, related to the Demised Premises,

  
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of any nature whatsoever; utilities separately metered; leasehold improvements to the Demised Premises; plate glass replacement in the Demised Premises; signs, subject to reasonable consent of
the UNIVERSITY; repair and/or replacement for any damage caused to UNIVERSITY property by the COMPANY or its invitees; commercial extermination service for the Demised Premises; telephone installation and call charges; and any modifications or
renovations made at the request or under the direction of the COMPANY, subject to the prior written approval of the UNIVERSITY. 

6.2    The COMPANY agrees it will comply with all federal and state laws and regulations and all UNIVERSITY Environmental
Health and Safety (“EHS”) requirements including, but not limited to, requirements relating to hazardous waste removal, radiation safety, and animal health and welfare. 

Prior to execution of this Lease and on an annual basis (and/or upon any changes in the business), the COMPANY will complete EHS and Research
Compliance questionnaires. The COMPANY will require employees to attend all EHS trainings required by University. The COMPANY agrees to allow EHS personnel to conduct inspections of the Demised Premises upon occupancy and at any time thereafter with
twenty-four (24) hours’ advance notice. Said inspections shall be conducted in the University’s sole discretion and for the sole benefit of the University and may not be relied upon by the COMPANY for any purpose. COMPANY shall be
solely responsible for complying with all environmental health and safety laws and regulations and with University EHS requirements and for conducting its own monitoring and site inspections to ensure compliance therewith. 

6.3    The COMPANY shall be solely responsible for hazardous waste removal and satisfying its obligation to comply with all
federal and state laws and regulations and all EHS requirements. The COMPANY shall coordinate such removal with the EHS and the UNIVERSITY’s hazardous waste service provider. The COMPANY is responsible for scheduling, for signing for the
shipment and for payment directly to the UNIVERSITY’s hazardous waste service provider. Pickup can be arranged at the TIP location where the COMPANY resides. The COMPANY can contract directly with the UNIVERSITY’s provider to have its
hazardous waste removed, but it will be the COMPANY’s obligation to make all arrangements with the provider. The UNIVERSITY may, but is not required to, provide packaging through the EHS Office. 

6.4    The COMPANY agrees to provide to the UNIVERSITY’S TIP management brief quarterly updates on: the COMPANY’S
scientific progress, new and existing grants, and any company business issues. The COMPANY agrees to meet with the TIP management quarterly to provide an overall detailed status update on the COMPANY’S space needs. In addition, the COMPANY will
provide its financial statements to TIP upon request from TIP management. 
 6.5    The COMPANY will provide, before the
Lease is fully executed, a current certificate of liability insurance, in accordance with Section 16 of this Lease. A current certificate will be supplied by the COMPANY annually each year thereafter. 

6.6    The COMPANY will make a best effort to provide comprehensive updates, utilizing
non-confidential data, on scientific progress, new and existing grants, and business issues of COMPANY to the TIP committee within six (6) months of the start date for the Lease Term and annually
thereafter. 
 6.7    The COMPANY will ensure that the Demised Premises are fully staffed and that the COMPANY’S TIP
lab is adequately funded without any lengthy interruption through the term of this Lease. 
 6.8    The COMPANY will
provide the UNIVERSITY quarterly data regarding jobs, revenue, and taxes generated by its business with the understanding that the UNIVERSITY agrees that this data will only be used in the aggregate for determining TIP program impact. 

  
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 6.9    The COMPANY will supply TIP with copies, as they are executed, of
all consulting arrangements and/or use and occupancy agreements, supporting its TIP Lab, with other entities at the UNIVERSITY. 

6.10    The COMPANY will supply to the UNIVERSITY, upon execution of this Lease or any Lease Amendment, a copy of its
incorporation papers including documents indicating current officer names and ownership. 
 6.11    The COMPANY will
develop a full business plan utilizing non-confidential and non-proprietary data relative to its TIP operation. In addition, COMPANY will provide its financial statements if requested by TIP management. 

6.12    In year two of its occupancy, the COMPANY agrees that it will consider a plan for an eventual transition from the
TIP facilities to an independent location at the end of the third year of the Lease Term. The TIP management will work with the COMPANY to develop the transition plan and provide services to support this effort. 

6.13    The COMPANY agrees that improvements to the Demised Premises are the responsibility of the COMPANY and may be made
only with the written consent of the UNIVERSITY. The Company further agrees that all such improvements shall be made in accordance with Section 14. 

6.14    The COMPANY agrees that all costs associated with removing furniture and cabinets, including storage, from the
Demised Premises will be the responsibility of COMPANY. 
 6.15    The COMPANY agrees that rent in Section 3.1 will
be paid from the start date of the Lease regardless of occupancy of the Demised Premises, unless such postponement of occupancy is a result of delay by the UNIVERSITY. 

6.16    The COMPANY will immediately notify UNIVERSITY’S Department of Public Safety regarding any injuries or
accidents occurring on the Demised Premises. 
 6.17    The COMPANY will promptly notify UNIVERSITY of any new employees
who will be working at the Demised Premises to ensure that they receive timely orientation relative to applicable University policies. 

7.    INTELLECTUAL PROPERTY: UNIVERSITY shall not claim ownership in any intellectual property to which it may be
entitled pursuant to Connecticut General Statutes Sections 10a-110 and 10a-110b, solely on the basis that such intellectual property was developed at or within the Demised Premises. Nothing in this or any other provision of this Lease shall prevent
the parties hereto from entering into a written agreement concerning ownership of intellectual property or rights thereto developed at or within the Demised Premises, nor shall the UNIVERSITY be prohibited from claiming an ownership interest in any
such intellectual property based on other factors contained in sections 10a-110 or 10a-110b. 
 8.    CONDITIONS OF
PREMISES: The Demised Premises are leased to and taken by the COMPANY “as is,” and in its present condition; provided, however, that nothing contained herein shall modify the UNIVERSITY’S obligations under Section 5
hereof, and this provision shall not apply to latent defects or conditions or to non-obvious structural matters. The COMPANY covenants that it will maintain the Demised Premises in a clean, orderly and safe condition, ordinary wear and tear
excepted, free from waste, and shall not permit any nuisance therein or the accumulation of trash or debris thereon or appurtenant thereto. 

  
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 9.    ASSIGNMENT AND SUBLETTING: The COMPANY shall not sublet the
Demised Premises, in whole or in part, or assign this Lease, or permit the Demised Premises to be used or occupied, in whole or in part, by others without the prior written consent of the UNIVERSITY, which consent shall not be unreasonably withheld,
delayed or conditioned. In the event such consent is given, the COMPANY shall not be relieved from any obligation under this Lease by reason of any such assignment or subletting. 

10.    UNIVERSITY’S RIGHT OF ENTRY: The COMPANY agrees that the UNIVERSITY shall have the right to enter upon
the Demised Premises at any time or from time to time for whatever purpose the UNIVERSITY deems necessary to enforce its rights or perform its obligations under this Lease, provided that UNIVERSITY will use its best efforts to avoid interfering with
COMPANY’S business on the Demised Premises. 
 11.    COMPLIANCE WITH LAWS: The COMPANY agrees that it will
use the Demised Premises so as to conform with and not violate any laws, regulations and/or requirements of the United States and/or the State of Connecticut and/or any ordinance, rule or regulation of the Town/City of Farmington, now or hereafter
made, relating to the use of the Demised Premises to the extent applicable, and the COMPANY shall indemnify and save the UNIVERSITY harmless from any fines, penalties or costs for violation of or noncompliance with the same, relating to the
operation of COMPANY’S business on the Demised Premises. The COMPANY will comply will all export control regulations, including the Export Administration Regulations (EAR) Title 15, sections 730-774 of the Code of Federal Regulations (CFR), and
the International Traffic in Arms Regulations (ITAR), 22 CFR sections 120-130. The UNIVERSITY does not provide export control advice to TIP Companies. The COMPANY acknowledges that certain exemptions from export control regulations applicable to the
University do not apply to private companies. 
 12.    LIENS: The COMPANY will not permit any lien for money
claimed against or owing by the COMPANY to be placed against the Demised Premises or the Building during the term hereof and should any such lien be recorded, the COMPANY shall, within fifteen (15) days after such lien is recorded, bond over or
pay and discharge same. Should any such lien be recorded and not be bonded over, released or discharged, the UNIVERSITY may, at the UNIVERSITY’S option (but without obligation so to pay or discharge such lien), pay and discharge any such lien,
at the cost and expense of the COMPANY. 
 13.    DEFAULT BY THE COMPANY; RIGHT TO TERMINATE: 

13.1    In the event the COMPANY shall: (a) fail to pay any rent payable pursuant to this Lease within ten
(10) days following written notice that same is due; or (b) if, for a period of thirty (30) days after notice thereof has been given to the COMPANY the COMPANY shall fail to perform or comply with any term hereof or any duty or
obligation imposed upon it by this Lease or by any other rule or regulation of the UNIVERSITY (provided, however, that if such cure cannot be accomplished within such thirty (30) days, and if the COMPANY promptly commences and diligently
pursues such cure, the COMPANY may have up to thirty (30) additional days to effect such a cure); or (c) if the COMPANY shall abandon the Demised Premises; or (d) there shall be filed by or against the COMPANY, or any guarantor of the
COMPANY’S obligations hereunder, a petition in bankruptcy or insolvency or for reorganization, dissolution, liquidation or for the appointment of a receiver or trustee of all or a portion of the COMPANY’S or such guarantor’s property
and in the case of an involuntary bankruptcy, the same is not discharged within sixty (60) days thereafter; or (e) if the COMPANY or such guarantor makes an assignment for the benefit of creditors or enters into an arrangement or admits
its inability to pay its debts as they become due, then and in any such event, the UNIVERSITY shall have the right, in addition to any other rights and remedies the UNIVERSITY may have, at the UNIVERSITY’S option, to enter upon the Demised
Premises, repossess, and enjoy the same in accordance with applicable law, as if this Lease had not been made, and thereupon this Lease shall terminate without prejudice. Upon demand by the UNIVERSITY, the COMPANY shall surrender to the UNIVERSITY
complete and peaceable possession of the Demised Premises. 

  
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 13.2    Without such re-entry as provided in Section 13.1, the
UNIVERSITY may recover possession of the Demised Premises in any manner permitted by law, including summary process, it being understood that no demand for rent or re-entry for condition broken, as at common law, shall be necessary to enable the
UNIVERSITY to recover such possession. 
 13.3    Upon the breach by the COMPANY of any terms and conditions of this
Lease, the parties hereto agree that this Lease may be terminated immediately at the option of the UNIVERSITY, without any obligations being thrust upon the UNIVERSITY of any nature whatsoever. 

13.4    Either party may terminate this Lease without cause or penalty upon sixty (60) days prior written notice. 

14.    ALTERATIONS AND IMPROVEMENTS: The COMPANY shall not make any alterations or improvements in or to the Demised
Premises without the prior written consent of the UNIVERSITY, which consent shall not be unreasonably withheld or delayed. Any approved alteration or improvement shall be done by contractors consented to by the UNIVERSITY, which consent shall not be
unreasonably withheld or delayed. Such approved alteration or improvement shall be made in a good and workmanlike manner and in a manner so that the structural integrity of the Building shall not be impaired. The COMPANY shall obtain all necessary
permits and, at the UNIVERSITY’S option, shall submit to the UNIVERSITY architectural renderings, insurance certificates and lien waivers as reasonably required by the UNIVERSITY. Upon the making of such alterations or improvements the same
shall become the property of the UNIVERSITY, provided, however, that should the UNIVERSITY require removal of such improvements, the UNIVERSITY shall notify the COMPANY in writing at the time consent is given that the UNIVERSITY will require that
the COMPANY remove the same at no expense to the UNIVERSITY and repair-any damage caused by such removal and that the Demised Premises shall be left by the COMPANY in the condition that the Demised Premises
were in at the commencement of the term of this Lease, ordinary wear and tear excepted. 
 15.    PERSONAL
PROPERTY: All personal property of every kind and description, which may at any time be on the Demised Premises, shall be at the COMPANY’s sole risk and the UNIVERSITY shall have no liability therefore. 

16.    INSURANCE: 

16.1    The COMPANY shall maintain its own insurance policy covering such personal property. 

16.2    The COMPANY shall obtain and keep in force at its sole expense during the Lease Term, the following insurance
coverage: 
  

	 	(a)	 Commercial General Liability 

 

							
	                      1.	 	Each Occurrence	  	 	$1,000,000	 
	                      2.	 	Personal and Advertising Injury	  	 	$1,000,000	 
	                      3.	 	General Aggregate	  	 	$2,000,000	 
	                      4.	 	Damage to Rented Premises	  	 	$   250,000	 

 The insurance shall provide for a retroactive date of placement prior to or coinciding with the effective date
of this Lease. 
  

	 	(b)	 Business Automobile Liability: Minimum Limits for Owned, Scheduled, Non Owned, or Hired Automobiles with a
combined single limit of not less than $1,000,000 per occurrence. 

  

	 	(c)	 Workers’ Compensation and Employer’s Liability: As required under state law. 

 

	 	(d)	 Such other insurance in such amounts which from time to time may reasonably be required by the mutual consent
of the UNIVERSITY and the COMPANY against other insurable hazards relating to performance. 

  
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 16.3    All policies of insurance provided for in this Section shall be
issued by insurance companies with general policyholder’s rating of not less than A- and a financial rating of not less than Class VIII as rated in the most current available A.M. Best Insurance Reports and be licensed to do business in
the State of Connecticut. All such policies shall be issued in the name of the COMPANY, and shall name, as Additional Insured, The State of Connecticut, University of Connecticut, with respects to liability arising out of operations, maintenance, or
use of the Demised Premises. Certificates thereof shall be delivered to the UNIVERSITY within thirty (30) days after Lease execution, and thereafter certificates thereof shall be delivered to the UNIVERSITY within ten (10) days prior to
the expiration of the term of each such policy, all at no cost to the UNIVERSITY. All certificates delivered to the UNIVERSITY shall contain a provision that the company writing said policy will give to the UNIVERSITY at least twenty
(20) days’ notice in writing in advance of any material change, cancellation, termination or lapse of the Effective Date of any reduction in the amounts of insurance below the requirements of the Lease. Policies shall waive the right of
recovery against the UNIVERSITY and shall be primary. 
 17.    INDEMNIFICATION: The COMPANY hereby indemnifies and
shall defend and hold harmless the UNIVERSITY, the State of Connecticut, its officers and its employees from and against any and all suits, actions, legal or administrative proceedings, claims, demands, liabilities, monetary loss, interest,
attorneys’ fees, costs and expenses of whatsoever kind or nature arising out of the performance of this agreement, including those arising out of injury to or death of COMPANY’s employees or subcontractors, whether arising before, during
or after completion of the services hereunder and in any manner directly or indirectly caused, occasioned or contributed to in whole or in part, by reason of any intentional, reckless or negligent act or omission of the COMPANY or its employees,
agents or subcontractors. 
 18.    SURRENDER OF PREMISES: At the expiration or other termination of this Lease,
the COMPANY will surrender the Demised Premises, after consultation with EH&S, to the UNIVERSITY in as good, broom-clean condition as that existing at the beginning of the Lease Term (excluding reasonable use and wear thereof), and except for
damage caused by unavoidable circumstances and any alterations or additions which may have been made by the COMPANY at the COMPANY’S expense with the written consent of the UNIVERSITY, or otherwise permitted hereunder. Any such alterations or
additions shall become, at no cost to the UNIVERSITY, the property of the UNIVERSITY, at the end of the Lease Term, unless as otherwise provided in Section 14 hereof. The UNIVERSITY reserves the right, however, at the termination or expiration
of the Lease, to demand, upon reasonable notice to the COMPANY, that the COMPANY remove such alterations and additions at the COMPANY’S expense, leaving the Demised Premises in substantially the same condition as it was at the beginning of the
Lease Term. 
 19.    HOLDING OVER: If at the expiration or termination of the Lease (including any applicable
extension option periods contained therein) the COMPANY shall hold over for any reason without the consent of the UNIVERSITY, the COMPANY thereafter shall be a tenant at sufferance, and the base rent shall be one hundred fifty percent (150%) of the
rent specified in the final year of the Lease. Any holding over by the COMPANY shall not operate to extend or renew this Lease. 

  
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 20.    NOTICES: All notices, demands or requests provided for or
permitted to be given pursuant to this Lease must be in writing. All notices demands and requests shall be deemed to have been properly served if sent by Federal Express or other reputable express carrier for next business day delivery, charges
billed to or prepaid by shipper; or if deposited in the United States mail, registered or certified with return receipt requested, proper postage prepaid, addressed as follows: 

If directed to the UNIVERSITY, written notice shall be addressed to: 

Technology Incubation Program 

University of Connecticut 

Advanced Technology Laboratory 

1392 Storrs Road, Unit 4213 

Storrs, CT 06269-1177 
 If
directed to the COMPANY, written notice shall be directed to: 
 David Lucchino 

Frequency Therapeutic, Inc. 

300 Technology Square, 8th Floor 

Cambridge, MA 02139 

21.    COMPLETE AGREEMENT: No prior stipulations, agreements or understandings, verbal or otherwise, of the parties
hereto or their agents, shall be valid or enforceable unless embodied in the provisions of this Lease. 

22.    NON-DISCRIMINATION: References in this Section to “Contract” shall mean this Lease and references to
“Contractor” shall mean this COMPANY. 
 (a)    For purposes of this Section, the following terms are defined as follows: (i)
“Commission” means the Commission on Human Rights and Opportunities; (ii) “Contract” and “contract” include any extension or modification of the Contract or contract; (iii) “Contractor” and
“contractor” include any successors or assigns of the Contractor or contractor; (iv) “Gender identity or expression” means a person’s gender-related identity, appearance or behavior, whether or not that gender-related
identity, appearance or behavior is different from that traditionally associated with the person’s physiology or assigned sex at birth, which gender-related identity can be shown by providing evidence including, but not limited to, medical
history, care or treatment of the gender-related identity, consistent and uniform assertion of the gender-related identity or any other evidence that the gender-related identity is sincerely held, part of a person’s core identity or not being
asserted for an improper purpose; (v) “good faith” means that degree of diligence which a reasonable person would exercise in the performance of legal duties and obligations; (vi) “good faith efforts” shall include, but not be
limited to, those reasonable initial efforts necessary to comply with statutory or regulatory requirements and additional or substituted efforts when it is determined that such initial efforts will not be sufficient to comply with such requirements;
(vii) “marital status” means being single, married as recognized by the State of Connecticut, widowed, separated or divorced; (viii) “mental disability” means one or more mental disorders, as defined in the most recent edition of
the American Psychiatric Association’s “Diagnostic and Statistical Manual of Mental Disorders”, or a record of or regarding a person as having one or more such disorders; (ix) “minority business enterprise” means any small
contractor or supplier of materials fifty-one percent or more of the capital stock, if any, or assets of which is owned by a person or persons: (1) who are active in the daily affairs of the enterprise, (2) who have the power to direct the
management and policies of the enterprise, and (3) who are members of a minority, as such term is defined in subsection (a) of Connecticut General Statutes § 32-9n; and (x) “public works contract” means any agreement between
any individual, firm or corporation and the State or any political subdivision of the State other than a municipality for construction, rehabilitation, conversion, extension, demolition or repair of a public building, highway or other changes or
improvements in real property, or which is financed in whole or in part by the State, including, but not limited to, matching expenditures, grants, loans, insurance or guarantees. 

For purposes of this Section, the terms “Contract” and “contract” do not include a contract where each contractor is (1) a political
subdivision of the state, including, but not limited to, a municipality, (2) a quasi-public agency, as defined in Conn. Gen. Stat. Section 1-120, (3) any other state, including but not limited to any federally recognized Indian tribal
governments, as defined in Conn. Gen. Stat. Section 1-267, (4) the federal government, (5) a foreign government, or (6) an agency of a subdivision, agency, state or government described in the immediately preceding enumerated items
(1), (2), (3), (4) or (5). 
 (b)    (1) The Contractor agrees and warrants that in the performance of the Contract such Contractor will
not discriminate or permit discrimination against any person or group of persons on the grounds of race, color, religious creed, age, marital status, national origin, ancestry, sex, gender identity or expression, mental retardation, mental
disability or physical disability, including, but not limited to, blindness, unless it is shown by such Contractor that such disability prevents performance of the work involved, in any manner prohibited by the laws of the United States or of the
State of Connecticut; and the Contractor further agrees to take affirmative action to insure that applicants with job-related qualifications are employed and that employees are treated when employed without regard to their race, color, religious
creed, age, marital status, national origin, ancestry, sex, gender identity or expression, mental retardation, mental disability or physical disability, including, but not limited to, blindness, unless it is shown by the Contractor that such
disability prevents performance of the work involved; (2) the Contractor agrees, in all solicitations or advertisements for employees placed by or on behalf of the Contractor, to state that it is an “affirmative action-equal opportunity
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accordance with regulations adopted by the Commission; (3) the Contractor agrees to provide each labor union or representative of workers with which the Contractor has a collective
bargaining Agreement or other contract or understanding and each vendor with which the Contractor has a contract or understanding, a notice to be provided by the Commission, advising the labor union or workers’ representative of the
Contractor’s commitments under this section and to post copies of the notice in conspicuous places available to employees and applicants for employment; (4) the Contractor agrees to comply with each provision of this Section and Connecticut
General Statutes §§ 46a-68e and 46a-68f and with each regulation or relevant order issued by said Commission pursuant to Connecticut General Statutes §§
46a-56, 46a-68e and 46a-68f; and (5) the Contractor agrees to provide the Commission on Human Rights and Opportunities with
such information requested by the Commission, and permit access to pertinent books, records and accounts, concerning the employment practices and procedures of the Contractor as relate to the provisions of this Section and Connecticut General
Statutes § 46a-56. If the contract is a public works contract, the Contractor agrees and warrants that he will make good faith efforts to employ minority business enterprises as subcontractors and
suppliers of materials on such public works projects. 
 (c)    Determination of the Contractor’s good faith efforts shall include,
but shall not be limited to, the following factors: The Contractor’s employment and subcontracting policies, patterns and practices; affirmative advertising, recruitment and training; technical assistance activities and such other reasonable
activities or efforts as the Commission may prescribe that are designed to ensure the participation of minority business enterprises in public works projects. 

(d)     The Contractor shall develop and maintain adequate documentation, in a manner prescribed by the Commission, of its good faith
efforts. 
 (e)    The Contractor shall include the provisions of subsection (b) of this Section in every subcontract or purchase
order entered into in order to fulfill any obligation of a contract with the State and such provisions shall be binding on a subcontractor, vendor or manufacturer unless exempted by regulations or orders of the Commission. The Contractor shall take
such action with respect to any such subcontract or purchase order as the Commission may direct as a means of enforcing such provisions including sanctions for noncompliance in accordance with Connecticut General Statutes §46a-56; provided if
such Contractor becomes involved in, or is threatened with, litigation with a subcontractor or vendor as a result of such direction by the Commission, the Contractor may request the State of Connecticut to enter into any such litigation or
negotiation prior thereto to protect the interests of the State and the State may so enter. 
 (f)    The Contractor agrees to comply
with the regulations referred to in this Section as they exist on the date of this Contract and as they may be adopted or amended from time to time during the term of this Contract and any amendments thereto. 

(g)    (1) The Contractor agrees and warrants that in the performance of the Contract such Contractor will not discriminate or permit
discrimination against any person or group of persons on the grounds of sexual orientation, in any manner prohibited by the laws of the United States or the State of Connecticut, and that employees are treated when employed without regard to their
sexual orientation; (2) the Contractor agrees to provide each labor union or representative of workers with which such Contractor has a collective bargaining Agreement or other contract or understanding and each vendor with which such
Contractor has a contract or understanding, a notice to be provided by the Commission on Human Rights and Opportunities advising the labor union or workers’ representative of the Contractor’s commitments under this section, and to post
copies of the notice in conspicuous places available to employees and applicants for employment; (3) the Contractor agrees to comply with each provision of this section and with each regulation or relevant order issued by said Commission
pursuant to Connecticut General Statutes § 46a-56; and (4) the Contractor agrees to provide the Commission on Human Rights and Opportunities with such information requested by the Commission, and
permit access to pertinent books, records and accounts, concerning the employment practices and procedures of the Contractor which relate to the provisions of this Section and Connecticut General Statutes §
46a-56. 
 (h)    The Contractor shall include the provisions of the foregoing paragraph in every
subcontract or purchase order entered into in order to fulfill any obligation of a contract with the State and such provisions shall be binding on a subcontractor, vendor or manufacturer unless exempted by regulations or orders of the Commission.
The Contractor shall take such action with respect to any such subcontract or purchase order as the Commission may direct as a means of enforcing such provisions including sanctions for noncompliance in accordance with Connecticut General Statutes
§ 46a-56; provided, if such Contractor becomes involved in, or is threatened with, litigation with a subcontractor or vendor as a result of such direction by the Commission, the Contractor may request the
State of Connecticut to enter into any such litigation or negotiation prior thereto to protect the interests of the State and the State may so enter. 

23.    EXECUTIVE ORDERS: This Contract is subject to the provisions of Executive Order No. Three of Governor Thomas
J. Meskill, promulgated June 16, 1971, concerning labor employment practices, Executive Order No. Seventeen of Governor Thomas J. Meskill, promulgated February 15, 1973, concerning the listing of employment openings and Executive Order No. Sixteen
of Governor John G. Rowland promulgated August 4, 1999, concerning violence in the workplace, all of which are incorporated into and are made a part of the Contract as if they had been fully set forth in it. The Contract may also be subject to
Executive Order No. 14 of Governor M. Jodi Rell, promulgated April 17, 2006, concerning procurement of cleaning products and services and to Executive Order No. 49 of Governor Dannel P. Malloy, promulgated May 22, 2015, mandating
disclosure of certain gifts to public employees and contributions to certain 

  
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candidates for office. If Executive Order 14 and/or Executive Order 49 are applicable, they are deemed to be incorporated into and are made a part of the Contract as if they had been fully set
forth in it. At the Contractor’s request, the Client Agency or DAS shall provide a copy of these orders to the Contractor. 

24.    POWER TO EXECUTE: The individual signing this Lease on behalf of the COMPANY certifies that s/he has full
authority to execute the same on behalf of the COMPANY and that this Lease has been duly authorized, executed and delivered by the COMPANY and is binding upon the COMPANY in accordance with its terms. The COMPANY shall provide a corporate resolution
or other signature authority documentation certifying that the individual executing this Lease has been authorized by the governing body of the COMPANY to sign on behalf of the COMPANY, signed on or after the date of the Lease execution by the
COMPANY. 
 25.    ETHICS AFFIDAVITS AND NONDISCRIMINATION CERTIFICATION REQUIREMENTS: 

26.1    The UNIVERSITY, as an agency of the State of Connecticut, requires that notarized Gift and Campaign Contribution
Certificates (Office of Policy and Management “OPM” Form 1) and Consulting Agreement Affidavits (OPM Form 5) accompany all State contracts/agreements with a value of $50,000 or more in a calendar or fiscal year. (Form 1 is also used with a
multi-year contract to update the initial certification on an annual basis.) 
 26.2    An executed Nondiscrimination
Certification must also be provided by the COMPANY at the time of Lease execution for all Leases with individuals, corporations and other entities, regardless of type, term, cost or value. The Certification requires the signer to disclose his/her
title and certify that the COMPANY has in place a properly-adopted policy, which supports the nondiscrimination requirements of Connecticut law. This Certification is required for all original Leases as well as Lease Amendments, signed on or after
the date of the Lease execution by the COMPANY. 
 26.    GOVERNING LAW: This Lease shall be governed by the laws
of the State of Connecticut, without regard to its principles of conflicts of laws. 
 27.    CLAIMS AGAINST THE
STATE: The COMPANY agrees that the sole and exclusive means for the presentation of any claim against the State arising from this Lease shall be in accordance with Chapter 53 of the Connecticut General Statutes (Claims Against the State) and
the COMPANY further agrees not to initiate any legal proceedings in any state or federal court in addition to, or in lieu of, said Chapter 53 proceedings. 

28.    MODIFICATION: The terms of this Lease may be modified or altered only by written Amendment to Lease between
the UNIVERSITY and the COMPANY, and no act or omissions of any employee or agent of the UNIVERSITY or the COMPANY shall alter, change or modify any of the provisions hereof. 

29.    APPROVAL OF BOARD OF TRUSTEES, STATE TREASURER AND ATTORNEY GENERAL: This Lease shall not be binding on the
UNIVERSITY or the COMPANY unless approved by the UNIVERSITY’S Board of Trustees and executed by authorized representatives of the State of Connecticut Treasurer and, if required, the State of Connecticut Attorney General. 

30.    FORCE MAJEURE: The UNIVERSITY and the COMPANY shall be excused for the period of delay in the performance of
any of their respective obligations, excepting monetary obligations hereunder, and shall not be considered in default when prevented from so performing due to a labor strike, riot, war, fire, flood or other casualty, or Acts of God so extensive as
to prevent the COMPANY from conducting business or preventing the COMPANY or the UNIVERSITY from complying with their obligations under the Lease. 

  
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 31.    STATE ELECTION ENFORCEMENT COMMISSION (SEEC) CAMPAIGN CONTRIBUTION
BAN: This Lease may be subject to the provisions of the State Election Enforcement Commission (SEEC) Campaign Contribution Ban depending on the value as described herein. For all State contracts, including this Lease, as defined in P.A. 10-1 having a value in a calendar year of $50,000 or more or a combination or series of such agreements or contracts having a value of $100,000 or more, the authorized signatory to this Lease expressly
acknowledges receipt of the State Elections Enforcement Commission’s notice advising state contractors of state campaign contribution and solicitation prohibitions, and will inform its principals of the contents of the notice. See SEEC NOTICE,
attached hereto as Exhibit A. 
 IN WITNESS WHEREOF, the parties have hereunto set their hands. 

 

									
	UNIVERSITY OF CONNECTICUT	 		 	Frequency Therapeutic, Inc.
					
	By:	 	 /s/ Radenka Maric
	 		 	By:	 	 /s/ David L. Lucchino

					
	Name:	 	Radenka Maric, Ph.D.	 		 	Name:	 	David Lucchino
					
	Title:	 	Vice President for Research	 		 	Title:	 	Chief Executive Officer
					
	Date:	 	  
	 		 	Date:	 	 7/22/2019

 APPROVED pursuant to C. G. S. § 4b-38(g): 

					
			
	 /s/ Linda R. Savitsky
	 	    Date:	 	    September 19, 2019        
	Shawn T. Wooden, State Treasurer	 		 	
	(Or designee,     Linda R. Savitsky                        )	 		 	
	(Title of designee:    Deputy Treasurer                  )	 		 	

 University Approved Template rev. 1/31/2017 

  
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 EXHIBIT A 

NOTICE 
 CONNECTICUT STATE
ELECTIONS ENFORCEMENT COMMISSION - Rev. 1/11 
 NOTICE TO EXECUTIVE BRANCH STATE CONTRACTORS AND PROSPECTIVE STATE CONTRACTORS OF
CAMPAIGN CONTRIBUTION AND SOLICITATION LIMITATIONS 
 This notice is provided under the authority of Connecticut General Statutes §9-612(g)(2),
as amended by P.A. 10-1, and is for the purpose of informing state contractors and prospective state contractors of the following law (italicized words are defined below “Definitions). 

CAMPAIGN CONTRIBUTION AND SOLICITATION LIMITATIONS 

No state contractor, prospective state contractor, principal of a state contractor or principal of a prospective state contractor, with regard to a
state contract or state contract solicitation with or from a state agency in the executive branch or a quasi-public agency or a holder, or principal of a holder of a valid prequalification certificate, shall make a contribution to
(i) an exploratory committee or candidate committee established by a candidate for nomination or election to the office of Governor, Lieutenant Governor, Attorney General, State Comptroller, Secretary of the State or State Treasurer,
(ii) a political committee authorized to make contributions or expenditures to or for the benefit of such candidates, or (iii) a party committee (which includes town committees). 

In addition, no holder or principal of a holder of a valid prequalification certificate, shall make a contribution to (i) an exploratory committee or
candidate committee established by a candidate for nomination or election to the office of State senator or State representative, (ii) a political committee authorized to make contributions or expenditures to or for the benefit of such
candidates, or (iii) a party committee. 
 On and after January 1, 2011, no state contractor, prospective state contractor, principal of a state
contractor or principal of a prospective state contractor, with regard to a state contract or state contract solicitation with or from a state agency in the executive branch or a quasi-public agency or a holder, or principal of a holder of a valid
prequalification certificate, shall knowingly solicit contributions from the state contractor’s or prospective state contractor’s employees or from a subcontractor or principals of the subcontractor on behalf of
(i) an exploratory committee or candidate committee established by a candidate for nomination or election to the office of Governor, Lieutenant Governor, Attorney General, State Comptroller, Secretary of the State or State Treasurer,
(ii) a political committee authorized to make contributions or expenditures to or for the benefit of such candidates, or (iii) a party committee. 

DUTY TO INFORM 
 State contractors and
prospective state contractors are required to inform their principals of the above prohibitions, as applicable, and the possible penalties and other consequences of any violation thereof. 

PENALTIES FOR VIOLATIONS 
 Contributions
or solicitations of contributions made in violation of the above prohibitions may result in the following civil and criminal penalties: 
 Civil
penalties—Up to $2,000 or twice the amount of the prohibited contribution, whichever is greater, against a principal or a contractor. Any state contractor or prospective state contractor which fails to make reasonable efforts to comply with
the provisions requiring notice to its principals of these prohibitions and the possible consequences of their violations may also be subject to civil penalties of up to $2,000 or twice the amount of the prohibited contributions made by their
principals. 
 Criminal penalties—Any knowing and willful violation of the prohibition is a Class D felony, which may subject the violator
to imprisonment of not more than 5 years, or not more than $5,000 in fines, or both. 
 CONTRACT CONSEQUENCES 

In the case of a state contractor, contributions made or solicited in violation of the above prohibitions may resulting the contract being voided. 

In the case of a prospective state contractor, contributions made or solicited in violation of the above prohibitions shall result in the contract described
in the state contract solicitation not being awarded to the prospective state contractor, unless the State Elections Enforcement Commission determines that mitigating circumstances exist concerning such violation. 

The State shall not award any other state contract to anyone found in violation of the above prohibitions for a period of one year after the election for
which such contribution is made or solicited, unless the State Elections Enforcement Commission determines that mitigating circumstances exist concerning such violation. 

Additional information may be found on the website of the State Elections Enforcement Commission, www.ct.gov/seec. Click on the link to
“Lobbyist/Contractor Limitations.” 
 DEFINITIONS 

“State contractor” means a person, business entity or nonprofit organization that enters into a state contract. Such person, business entity or
nonprofit organization shall be deemed to be a state contractor until December thirty-first of the year in which such contract terminates. “State contractor” does not include a municipality or any other political subdivision of the state,
including any entities or associations duly created by the municipality or political subdivision exclusively amongst themselves to further any purpose authorized by statute or charter, or an employee in the executive or legislative branch of state
government or a quasi-public agency, whether in the classified or unclassified service and full or part-time, and only in such person’s capacity as a state or quasi-public agency employee. 

“Prospective state contractor” means a person, business entity or nonprofit organization that (i) submits a response to a state contract
solicitation by the state, a state agency or a quasi-public agency, or a proposal in response to a request for proposals by the state, a state agency or a quasi-public agency, until the contract 

  
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has been entered into, or (ii) holds a valid prequalification certificate issued by the Commissioner of Administrative Services under section 4a-100. “Prospective state contractor”
does not include a municipality or any other political subdivision of the state, including any entities or associations duly created by the municipality or political subdivision exclusively amongst themselves to further any purpose authorized by
statute or charter, or an employee in the executive or legislative branch of state government or a quasi-public agency, whether in the classified or unclassified service and full or part-time, and only in such person’s capacity as a state or
quasi-public agency employee. 
 “Principal of a state contractor or prospective state contractor” means (i) any individual who is a member
of the board of directors of, or has an ownership interest of five per cent or more in, a state contractor or prospective state contractor, which is a business entity, except for an individual who is a member of the board of directors of a nonprofit
organization, (ii) an individual who is employed by a state contractor or prospective state contractor, which is a business entity, as president, treasurer or executive vice president, (iii) an individual who is the chief executive
officer of a state contractor or prospective state contractor, which is not a business entity, or if a state contractor or prospective state contractor has no such officer, then the officer who duly possesses comparable powers and duties,
(iv) an officer or an employee of any state contractor or prospective state contractor who has managerial or discretionary responsibilities with respect to a state contract, (v) the spouse or a dependent child who is eighteen
years of age or older of an individual described in this subparagraph, or (vi) a political committee established or controlled by an individual described in this subparagraph or the business entity or nonprofit organization that is the state
contractor or prospective state contractor. 
 “State contract” means an agreement or contract with the state or any state agency or any
quasi-public agency, let through a procurement process or otherwise, having a value of fifty thousand dollars or more, or a combination or series of such agreements or contracts having a value of one hundred thousand dollars or more in a calendar
year, for (i) the rendition of services, (ii) the furnishing of any goods, material, supplies, equipment or any items of any kind, (iii) the construction, alteration or repair of any public building or public work, (iv) the
acquisition, sale or lease of any land or building, (v) a licensing arrangement, or (vi) a grant, loan or loan guarantee. “State contract” does not include any agreement or contract with the state, any state agency or any
quasi-public agency that is exclusively federally funded, an education loan, a loan to an individual for other than commercial purposes or any agreement or contract between the state or any state agency and the United States Department of the Navy
or the United States Department of Defense. 
 “State contract solicitation” means a request by a state agency or quasi-public agency, in whatever
form issued, including, but not limited to, an invitation to bid, request for proposals, request for information or request for quotes, inviting bids, quotes or other types of submittals, through a competitive procurement process or another process
authorized by law waiving competitive procurement. 
 “Managerial or discretionary responsibilities with respect to a state contract” means having
direct, extensive and substantive responsibilities with respect to the negotiation of the state contract and not peripheral, clerical or ministerial responsibilities. 

“Dependent child” means a child residing in an individual’s household who may legally be claimed as a dependent on the federal income tax of
such individual. 
 “Solicit” means (A) requesting that a contribution be made, (B) participating in any fund-raising activities for a
candidate committee, exploratory committee, political committee or party committee, including, but not limited to, forwarding tickets to potential contributors, receiving contributions for transmission to any such committee or bundling
contributions, (C) serving as chairperson, treasurer or deputy treasurer of any such committee, or (D) establishing a political committee for the sole purpose of soliciting or receiving contributions for any committee. Solicit does not
include: (i) making a contribution that is otherwise permitted by Chapter 155 of the Connecticut General Statutes; (ii) informing any person of a position taken by a candidate for public office or a public official, (iii) notifying
the person of any activities of, or contact information for, any candidate for public office; or (iv) serving as a member in any party committee or as an officer of such committee that is not otherwise prohibited in this section. 

“Subcontractor” means any person, business entity or nonprofit organization that contracts to perform part or all of the obligations of a state
contractor’s state contract. Such person, business entity or nonprofit organization shall be deemed to be a subcontractor until December thirty first of the year in which the subcontract terminates. “Subcontractor” does not include
(i) a municipality or any other political subdivision of the state, including any entities or associations duly created by the municipality or political subdivision exclusively amongst themselves to further any purpose authorized by statute or
charter, or (ii) an employee in the executive or legislative branch of state government or a quasi-public agency, whether in the classified or unclassified service and full or part-time, and only in such person’s capacity as a state or
quasi-public agency employee. 
 “Principal of a subcontractor” means (i) any individual who is a member of the board of directors of, or has
an ownership interest of five per cent or more in, a subcontractor, which is a business entity, except for an individual who is a member of the board of directors of a nonprofit organization, (ii) an individual who is employed by a
subcontractor, which is a business entity, as president, treasurer or executive vice president, (iii) an individual who is the chief executive officer of a subcontractor, which is not a business entity, or if a subcontractor has no such
officer, then the officer who duly possesses comparable powers and duties, (iv) an officer or an employee of any subcontractor who has managerial or discretionary responsibilities with respect to a subcontract with a state contractor,
(v) the spouse or a dependent child who is eighteen years of age or older of an individual described in this subparagraph, or (vi) a political committee established or controlled by an individual described in this subparagraph or the
business entity or nonprofit organization that is the subcontractor. 

  
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 Exhibit 10.7 

SECOND AMENDED AND RESTATED 

EXECUTIVE EMPLOYMENT AGREEMENT 

This Second Amended and Restated Executive Employment Agreement (the “Agreement”) is entered into as of September 20, 2019, by
and between Frequency Therapeutics, Inc., a Delaware corporation (“Frequency” or the “Company”), and David Lucchino (“Mr. Lucchino” or the “Executive”) (each a “Party” and collectively, the
“Parties”). 
 WHEREAS, the Company and Executive previously entered into an Executive Employment Agreement, effective as of
June 1, 2016, as amended and restated on August 31, 2018 (the “Prior Agreement”); 
 WHEREAS, in connection with the
Company’s initial public offering of stock pursuant to an effective registration statement filed under the Securities Act of 1933, as amended (the “IPO”), the Company wishes to continue to employ the Executive in the position of Chief
Executive Officer, and the Executive and the Company desire to amend and restate the Prior Agreement to set forth in a written agreement the terms and conditions of the Executive’s continued employment by and services to the Company; 

NOW, THEREFORE, for good and valuable consideration, the receipt and adequacy of which is hereby acknowledged, the Parties agree to amend and
restate the Prior Agreement in its entirety as set forth herein, and the parties hereto further agree as follows: 
 1.
Employment. 
 a. Effective on the closing of the IPO (the “Effective Date”), and subject to the terms and
conditions of this Agreement, the Company shall continue to employ the Executive as President and Chief Executive Officer (“CEO”), reporting only to the Company’s Board of Directors (the “Board”). Executive will have the
responsibilities, duties, and authority customarily assigned to the President and CEO position within corporations of the size, type and nature similar to that of the Company. The Executive shall serve as a member of the Board while he is the CEO.

 b. During his employment with the Company, and excluding any periods of vacation and sick
leave to which the Executive is entitled, the Executive shall devote substantially all of his full business attention and time to the Company’s business and affairs and shall use his best efforts to carry out such responsibilities faithfully
and efficiently, and in accordance with Company policy and procedures. Subject to Company approval where required by applicable policy, it shall not be considered a violation of the foregoing for the Executive to (i) serve on corporate, civic
or charitable boards or committees, (ii) serve as a member of the board of directors of up to two (2) organizations that are not competitors of the Company (or such greater number as approved by the Board), (iii) deliver lectures, fulfill
speaking engagements or teach at educational institutions and (iv) manage personal investments, so long as such activities do not materially interfere with the performance of the Executive’s responsibilities on behalf of the Company,
violate the Company’s standards of conduct then in effect or raise a conflict under the Company’s conflict of interest policies as then in effect. For the avoidance of doubt, the Board has already consented to Executive’s service on
the boards of directors set forth on Exhibit A hereto. 
 As an officer of the Company, the Executive shall be entitled to
indemnification and other related protections, to the fullest extent allowed under the law and the Company’s Certificate of Incorporation, as may be amended from time to time. Executive will also be covered under a directors and officers
liability insurance policy paid for by the Company to the extent that the Company maintains such a liability insurance policy now or in the future. 

2. At-Will Employment. The Parties agree that Executive’s employment with the
Company will be “at-will” employment and may be terminated at any time by either Party with or without cause or notice, subject to the provisions of Section 5 of this Agreement. Executive
understands and agrees that neither his job performance nor promotions, commendations, bonuses or the like from the Company give rise to or in any way serve as the basis for modification, amendment, or extension, by implication or otherwise, of his
employment with the Company. The term “Employment Period” means the period during which the Executive is employed under this Agreement. 

  
 2 

 3. Compensation; Benefits; Equity. 

a. Base Salary. As compensation for the Executive’s services hereunder, during the Employment Period, the Company will pay the
Executive a base salary at the annual rate of $525,000 (“Base Salary”), payable at such times and intervals as the Company pays the base salaries of its other executive employees. Base Salary shall be reviewed at least annually by the
Board for possible increase. The Base Salary shall not be reduced after any such increase (other than a general salary reduction that applies to all of the Company’s senior executive staff), and the term “Base Salary” shall thereafter
refer to the Base Salary as so modified. 
 b. Annual Bonus. During the Employment Period, the Executive will be eligible for an
annual bonus for each full year of employment targeted at 55% of his Base Salary (the “Target Bonus”), based on the attainment of mutually agreed performance objectives between the Executive and the Board established in writing during the
first quarter of the applicable bonus year. The Board shall, in good faith, determine whether the Executive has attained such objectives and, as a result, the amount of any bonus (the “Annual Bonus”). The Annual Bonus shall be calculated
and paid no later than March 15 of the year following the calendar year for which performance was measured and the Executive was eligible for such Target Bonus. 

c. Long-Term Incentive Awards. The Executive shall be eligible for other or additional long-term incentives in the discretion of the
Board. Such other or additional incentive awards shall be on a level, and on terms and conditions, that are commensurate with his position and responsibilities at the Company and appropriate in light of corresponding incentive awards to other senior
executives of the Company. 
 d. Equity. 

(i) As a founder of the Company, Executive purchased restricted stock from the Company pursuant to a Restricted Stock Agreement entered into
on November 13, 2014 (the “Founder’s RSA”). The Founder’s RSA is incorporated herein by reference and remains in full force and effect. The Executive also acknowledges having received options to purchase shares of the
Company’s common stock and that the terms of such options remain in full force and effect. 

  
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 (ii) If all or a portion of the Company’s assets are spun out into a newly created
entity or the Company is reorganized into a limited liability company (“LLC”) or holding company structure (with subsidiaries), the Company agrees that Executive’s ownership of such entities and/or the LLC holding company, as the case
may be, shall represent the same relative percentage ownership as it was immediately prior to the spin out or reorganization. For the avoidance of doubt, if such assets are contributed to a newly created entity in which the Company and a third party
own an equity interest in such newly created entity (e.g., a joint venture), Executive shall be deemed to have the same relative ownership of such subsidiary or entity for purposes of the foregoing sentence. 

(iii) Executive shall be eligible to receive equity awards under the Incentive Plan annually or on such regular basis as awards are made to
employees of the Company. 
 (iv) In the event of a Change of Control (as defined below), 100% of Executive’s then outstanding
time-based Equity Awards will accelerate and vest. 
 e. Benefits. During the Employment Period, the Executive shall participate in
all employee benefit plans, programs, arrangements and perquisites made available generally to the Company’s senior executives or to its employees generally. Executive shall also receive such additional fringe benefits and perquisites as the
Company may, in its discretion, from time-to-time provide. 

f. Vacation. During the Employment Period, the Executive shall be entitled to four (4) weeks of paid vacation time per calendar
year. 
 g. Reimbursement of Expenses. The Company shall reimburse the Executive for all out-of-pocket business expenses incurred by the Executive during the Employment Period in furtherance of the Company’s business in accordance with Company policies, upon presentation by Executive of
documentation, expense statements, receipts, vouchers and/or such other supporting information as the Company may reasonably request. The expenses eligible for reimbursement in one taxable year may not affect the expenses eligible for reimbursement
in any other taxable year; reimbursement will be made in accordance with the Company’s normal practices; and the right to reimbursement is not subject to liquidation or exchange for another benefit. 

  
 4 

 h. Financial and Legal Services. In addition, the Company shall reimburse Executive
for his reasonable legal costs incurred in the development and negotiation of this Agreement (and any subsequent amendment of this Agreement), up to a maximum of $7,500 for each calendar year during the Agreement is being developed, amended and/or
negotiated. 
 4. Termination and Defined Terms. As set forth in Section 2, Executive’s employment is “at-will” and may be terminated at any time by either Party with or without cause or notice. However, under certain terminations of employment, Executive will be eligible to receive benefits set forth in
Section 5. This Section 4 sets forth defined meanings of certain terms related to termination of employment. 
 a. Cause.
For purposes of this Agreement, “Cause” means: (i) misappropriation of the funds or property of the Company; (ii) conviction of, a felony or any crime involving fraud, embezzlement or any other act of moral turpitude;
(iii) willful and gross misconduct or neglect in carrying out his duties under this Agreement (not due to sickness or disability), resulting, in either case, in material economic harm to the Company; provided, however, that this
clause (iii) shall not apply to any conduct by the Executive if the Executive believed in good faith that such conduct was in, or not opposed to, the best interests of the Company unless such conduct is inconsistent with a direct instruction
from the Board; (iv) Executive’s unauthorized use or disclosure of any proprietary information or trade secrets of the Company or any other party to whom Executive owes an obligation of
non-disclosure as a result of Executive’s relationship with the Company; or (v) Executive’s repeated failure to substantially perform Executive’s assigned duties or responsibilities as an
employee as directed or assigned by the Board (other than a failure resulting from the Executive’s disability) after written notice thereof from the Board to Executive describing in reasonable detail Executive’s failure to perform such
duties or responsibilities and Executive having had the opportunity to address the Board, with counsel, regarding such alleged failures and Executive’s failure to remedy same within thirty (30) 

  
 5 

 
days of receiving written notice. The Company shall give the Executive notice of termination specifying which of the foregoing provisions is applicable. With respect to any action or inaction for
Cause that is curable (as reasonably determined by the Board in good faith), Executive will be afforded a cure period of not less than 30 days following the date of notice to cure any action or inaction determined to be Cause. 

b. Good Reason. For purposes of this Agreement “Good Reason” means Executive’s resignation following (i) being
removed as CEO of the Company without the Executive’s express written consent or material and adverse changes to Executive’s duties, status, reporting relationship, authority or responsibilities; (ii) a material reduction in
Executive’s Base Salary; (iii) a material diminution in the budget over which the Executive retains authority; (iv) the change of the Executive’s principal place of employment to a location more than twenty-five miles from
Boston, MA; (v) the failure of the Company to obtain the assumption in writing of its obligation to fully perform this Agreement by any successor to all or substantially all of the assets of the Company on or before the closing date of any
merger, consolidation, sale or similar transaction; or (vi) any other material breach by the Company (or any affiliate) of a provision of this Agreement or any agreement between the Executive and the Company (or any affiliate). The Executive
shall give the Company Notice of Good Reason specifying which of the foregoing provisions is applicable within ninety (90) days of the occurrence of such event and the factual basis therefor, and if the Company fails to remedy such condition
within thirty (30) days of receipt of such note, the Executive’s last day of actual employment with the Company shall be the 30th business day after such Notice is given or such other date as the Company and the Executive shall agree. 

c. Disability. For purposes of this Agreement, the term “Disability” means the inability of the Executive, due to a physical
or mental disability, for a period of 180 days, whether or not consecutive, during any 360-day period, to perform the services contemplated under this Agreement. A determination of disability shall be made by
a physician satisfactory to both the Executive and the Company, provided that if the Executive and the Company do not agree on a physician, the Executive and Company shall each select a physician and these two together shall select a third
physician, whose determination as to disability shall be binding on all parties; 

  
 6 

 5. Effect of Employment Termination. 

a. By the Company for Cause or by the Executive without Good Reason. If the Executive’s employment is terminated by the Company
for Cause or by the Executive without Good Reason, the Company shall pay to the Executive the compensation and benefits otherwise payable to him through the last day of his actual employment, all reimbursements for expenses incurred on the
Company’s behalf and any annual bonus payment from the prior year that was unpaid as of the date of termination (the “Accrued Obligations”). 

b. By the Executive for Good Reason; by the Company without Cause Or Upon Non-Renewal of this
Agreement for Good Reason or Without Cause, or upon Death or Disability of Executive. If the Executive’s employment is terminated by the Executive for Good Reason or by the Company other than for Cause, or in the case of the death or
Disability of the Executive (in each case, a “Qualifying Termination”), the Executive, or his estate in the case of Executive’s death, shall be entitled to the following, subject to the release requirement set forth in
Section 5(d): 
 (i) Severance payment. The Company shall pay to the Executive or his estate the Accrued Obligations plus an
amount equal to (A) Executive’s monthly Base Salary (disregarding any salary reduction that forms the basis for Good Reason) for a period equal to twelve (12) months (the “Severance Measurement Period”), (B) 100% of
Executive’s full Target Bonus for the year that includes the termination of employment assuming 100% achievement of the performance metrics for such year (for illustrative purposes, if Executive is terminated in 2017, then he receives 100% of
the Target Bonus for 2018 under this clause (B) assuming 100% achievement of the performance metrics for 2018) and (C) an additional payment equal to Executive’s Target Bonus for the year that includes the termination of employment,
but prorated based on the portion of the year that Executive was employed prior to termination (for illustrative purposes, if Executive is terminated on July 1, 2018, then he receives 50% of this Target Bonus

  
 7 

 
for 2018 under this clause (C) because he was employed for 50% of 2018). All payments under this subsection (i) shall be paid less applicable tax withholding in a single lump-sum payment on the first Company payroll date after the Release Deadline (as defined below), but in no event later than March 15th of the year following the
year of the Qualifying Termination. 
 (ii) Equity Awards. Prior to a Change of Control, notwithstanding any provision of any plan,
award or agreement to the contrary, all equity awards granted to the Executive by the Company (or an affiliate), including, but not limited to, the options held by Executive and the Founder’s Shares (collectively, the “Equity Awards”)
shall, on the termination date, accelerate and vest as to a number of shares that would have vested had Executive remained employed through the date six (6) months following the termination of employment date. For clarity, acceleration under
this Section 5(b)(ii) is limited to time-based Equity Awards. In addition, the Company agrees that in connection with such termination that Executive may request and shall receive a reasonable extension of the exercise period under
Executive’s option Equity Awards, or some other mutually agreeable and reasonable arrangement to enable the Executive to exercise all or a portion of such vested option Equity Awards following termination. Executive acknowledges that the
foregoing may have tax consequences to Executive and that Executive has sought his own tax advice in connection therewith. 
 (iii)
Benefits. In the event that the Executive and/or his dependents participate in any health insurance plan offered by the Company as of the Executive’s last day of actual employment, if the Executive and/or his dependents elect
continuation coverage under the Consolidated Omnibus Budget Reconciliation Act of 1985, as amended (“COBRA”), the Company will pay any premiums associated with such continuation coverage during the Severance Measurement Period. 

c. Change of Control-Related Termination. Notwithstanding Section 5(b), in the event of a Qualifying Termination following a
Change of Control (as defined below), then Executive will receive the same benefits set forth in Section 5(b), except that (x) the Severance Measurement Period for purposes of Section 5(c)(i) and 5(c)(iii) will be eighteen
(18) months and (y) in lieu of Section 5(c)(ii), 100% of Executive’s Equity Awards will accelerate and vest, including any performance-based vesting Equity Awards which will accelerate and vest at target level of achievement. 

  
 8 

 For purposes of this Agreement, “Change of Control” means the occurrence of any of
the following events after the Effective Date: 
 (i) any one person, or more than one person acting as a group (“Person”) becomes
the beneficial owner, directly or indirectly, of securities of the Company representing fifty percent (50%) or more of the combined voting power of the Company’s then outstanding securities, excluding, however, any Person (or group of which
such Person forms a part and of which such Person owns at least 20%) that is currently an Affiliate of the Company; or 
 (ii) during any
period of two (2) consecutive years (not including any period prior to the Effective Date), individuals who at the beginning of such period constitute the Board (and any new director, whose election by the Company’s stockholders was
approved by a vote of at least a majority of the directors then still in office who either were directors at the beginning of the period or whose election or nomination for election was so approved), cease for any reason to constitute a majority
thereof; 
 (iii) the consummation of (A) a sale or disposition of all or substantially all of the Company’s assets; or
(B) a merger, consolidation, or reorganization of the Company with or involving any other corporation, other than a merger, consolidation, or reorganization that would result in the holders of voting securities of the Company outstanding
immediately prior thereto owning more than fifty percent (50%) of the combined voting power of the voting securities of the Company (or such surviving entity) outstanding immediately after such merger, consolidation, or reorganization, excluding,
however, any Person (or group of which such Person forms a part and of which such Person owns at least 20%) that is currently an Affiliate of the Company; or 

(iv) the approval of a plan of complete liquidation of the Company by the stockholders of the Company. 

  
 9 

 d. Release Requirement. The receipt of any severance payments or benefits under
Sections 5(b) or (c) (other than the Accrued Obligations) pursuant to this Agreement is subject to Executive signing and not revoking the Company’s customary separation and release of claims agreement (the “Release”), which must
become effective and irrevocable no later than the 60th day following Executive’s termination of employment (the “Release Deadline”). If the Release does not become effective and irrevocable by the Release Deadline, Executive will
forfeit any right to severance payments or benefits under this Agreement. In no event will severance payments or benefits be paid or provided until the Release actually becomes effective and irrevocable. The Release will not include any additional
post-employment restrictive covenants other than as set forth in Executive’s Founder Non-Competition and Non-Solicitation Agreement (the “Non-Compete Agreement”) or Executive’s Founder Invention and Non-Disclosure Agreement (the “Proprietary Agreement”). 

e. No Mitigation; No Set Off. In the event of any termination of employment hereunder, the Executive shall be under no obligation to
seek other employment and there shall be no offset against any amounts due to the Executive under this Agreement on account of any remuneration attributable to any subsequent employment that Executive may obtain. 

6. Section 409A. In compliance with Section 409A of the Internal Revenue Code of 1986, as amended
(“Section 409A”) (to the extent applicable), and notwithstanding any other provision of this Agreement: (i) the amount of expenses eligible for reimbursement and the provision of in-kind
benefits during any calendar year shall not affect the amount of expenses eligible for reimbursement or the provision of in-kind benefits in any other calendar year; (ii) the reimbursement of an eligible
expense shall be made on or before December 31 of the calendar year following the calendar year in which the expense was incurred; (iii) reimbursement or right to an in-kind benefit shall not be
subject to liquidation or exchange for another benefit; and (iv) each reimbursement payment or provision of in-kind benefit shall be one of a series of separate payments (and each shall be construed as a
separate identified payment) for purposes of Section 409A. 

  
 10 

 A termination of employment or employment termination under this Agreement shall be deemed
to occur only if it meets the requirements of a “Separation from Service” as defined at Treasury Regulation Section §1.409A-1(h). 

Notwithstanding any other provisions of this Agreement to the contrary, and solely if and to the extent necessary for compliance with
Section 409A and not otherwise eligible for exclusion from the requirements of Section 409A, if as of the date of the Executive’s separation from service from the Company, he is deemed to be a “specified employee” (within
the meaning of Section 409A), no payment or other distribution required to be made to the Executive hereunder (including any payment of cash, any transfer of property and any provision of taxable benefits) solely as a result of his separation
from service shall be made until the date that is the earlier of (1) the first day of the seventh month following the date on which the Executive separates from service with the Company or (2) the date of the Executive’s death, if and
to the extent required under Section 409A. Upon the expiration of the foregoing delay period, all payments and benefits delayed pursuant to the foregoing shall be paid or reimbursed to the Executive in a lump sum, and all remaining payments and
benefits due under this Agreement shall be paid or provided in accordance with the normal payment dates specified for them herein. 
 This
Agreement shall be interpreted and at all times administered in a manner that avoids the inclusion of compensation in income under Section 409A, or the payment of increased taxes, excise taxes or other penalties under Section 409A. The
Parties intend this Agreement to be in compliance with or exempt from Section 409A. 
 7. Succession and
Assignment. This Agreement shall be binding upon and inure to the benefit of the Parties named herein and their respective successors and permitted assigns. No Party may assign either this Agreement or any of its rights, interests or
obligations hereunder without the prior written approval of the other Party; provided, that the Company (a) may assign its rights, interests or obligations hereunder to a subsidiary, subdivision or affiliate, provided that the Company shall
remain responsible to the Executive for such obligations in the event they are not met by such assignee; or (b) shall assign its obligations hereunder to a person, corporation, organization or other entity that acquires (whether by stock
purchase or merger or otherwise) all or substantially all of the business or assets of the Company. 

  
 11 

 8. Arbitration. 

a. Arbitration. IN CONSIDERATION OF EXECUTIVE’S EMPLOYMENT WITH THE COMPANY, ITS PROMISE TO ARBITRATE ALL EMPLOYMENT-RELATED
DISPUTES, AND EXECUTIVE’S RECEIPT OF THE COMPENSATION, PAY RAISES AND/OR OTHER BENEFITS PAID TO EXECUTIVE BY THE COMPANY, AT PRESENT AND IN THE FUTURE, EXECUTIVE AGREES THAT ANY AND ALL CONTROVERSIES, CLAIMS, OR DISPUTES WITH ANYONE (INCLUDING
THE COMPANY AND ANY EMPLOYEE, OFFICER, DIRECTOR, SHAREHOLDER OR BENEFIT PLAN OF THE COMPANY, IN THEIR CAPACITY AS SUCH OR OTHERWISE), ARISING OUT OF, RELATING TO, OR RESULTING FROM EXECUTIVE’S EMPLOYMENT OR RELATIONSHIP WITH THE COMPANY OR THE
TERMINATION OF EXECUTIVE’S EMPLOYMENT OR RELATIONSHIP WITH THE COMPANY, INCLUDING ANY BREACH OF THIS AGREEMENT, SHALL BE SUBJECT TO BINDING ARBITRATION UNDER THE ARBITRATION PROVISIONS SET FORTH IN THE GENERAL LAWS OF MASSACHUSETTS, CHAPTER 251
(THE “RULES”) AND PURSUANT TO MASSACHUSETTS LAW. THE FEDERAL ARBITRATION ACT SHALL CONTINUE TO APPLY WITH FULL FORCE AND EFFECT. EXECUTIVE AGREES THAT EXECUTIVE MAY ONLY COMMENCE AN ACTION IN ARBITRATION, OR ASSERT COUNTERCLAIMS IN
AN ARBITRATION, ON AN INDIVIDUAL BASIS AND, THUS, EXECUTIVE HEREBY WAIVES EXECUTIVE’S RIGHT TO COMMENCE OR PARTICIPATE IN ANY CLASS OR COLLECTIVE ACTION(S) AGAINST THE COMPANY, AS PERMITTED BY LAW. DISPUTES THAT EXECUTIVE AGREES TO ARBITRATE,
AND THEREBY AGREE TO WAIVE ANY RIGHT TO A TRIAL BY JURY, INCLUDE ANY STATUTORY CLAIMS UNDER LOCAL, STATE, OR FEDERAL LAW, INCLUDING, BUT NOT LIMITED TO, CLAIMS UNDER TITLE VII OF THE CIVIL RIGHTS ACT OF 1964, THE CIVIL RIGHTS ACT OF 1991, THE FAIR
LABOR STANDARDS ACT, THE AMERICANS WITH DISABILITIES ACT OF 1990, THE AGE DISCRIMINATION IN EMPLOYMENT ACT OF 1967, THE OLDER WORKERS BENEFIT PROTECTION ACT, THE SARBANES-OXLEY ACT, THE WORKER ADJUSTMENT AND RETRAINING NOTIFICATION ACT, THE FAIR
CREDIT REPORTING ACT, THE EMPLOYEE RETIREMENT INCOME SECURITY ACT OF 1974, THE FAMILY AND MEDICAL LEAVE ACT, THE MASSACHUSETTS FAIR EMPLOYMENT PRACTICES ACT, THE MASSACHUSETTS CIVIL RIGHTS ACT, THE MASSACHUSETTS EQUAL PAY ACT, THE MASSACHUSETTS
EQUAL RIGHTS ACT, THE GENERAL LAWS OF MASSACHUSETTS, CLAIMS RELATING TO EMPLOYMENT STATUS, CLASSIFICATION AND RELATIONSHIP WITH THE COMPANY, CLAIMS OF HARASSMENT, DISCRIMINATION AND WRONGFUL TERMINATION, AND ANY STATUTORY OR COMMON LAW CLAIMS.
EXECUTIVE ALSO AGREES TO ARBITRATE ANY AND ALL DISPUTES ARISING OUT OF OR RELATING TO THE INTERPRETATION OR APPLICATION OF THIS AGREEMENT TO ARBITRATE, BUT NOT DISPUTES ABOUT THE ENFORCEABILITY, REVOCABILITY OR VALIDITY OF THIS AGREEMENT TO
ARBITRATE OR ANY PORTION HEREOF OR THE CLASS, COLLECTIVE AND REPRESENTATIVE PROCEEDING WAIVER HEREIN. WITH 

  
 12 

 
RESPECT TO ALL SUCH CLAIMS AND DISPUTES THAT EXECUTIVE AGREES TO ARBITRATE, EXECUTIVE HEREBY EXPRESSLY AGREES TO WAIVE, AND DO WAIVE, ANY RIGHT TO A TRIAL BY JURY. NOTWITHSTANDING THE FOREGOING,
EXECUTIVE UNDERSTANDS THAT NOTHING IN THIS AGREEMENT CONSTITUTES A WAIVER OF EXECUTIVE’S RIGHTS UNDER SECTION 7 OF THE NATIONAL LABOR RELATIONS ACT. EXECUTIVE FURTHER UNDERSTANDS THAT THIS AGREEMENT TO ARBITRATE ALSO APPLIES TO ANY DISPUTES
THAT THE COMPANY MAY HAVE AGAINST EXECUTIVE. 
 b. Procedure. EXECUTIVE AGREES THAT ANY ARBITRATION WILL BE ADMINISTERED BY JUDICIAL
ARBITRATION & MEDIATION SERVICES, INC. (“JAMS”), PURSUANT TO ITS EMPLOYMENT ARBITRATION RULES & PROCEDURES (THE “JAMS RULES”), PROVIDED, HOWEVER, THAT THE JAMS RULES SHALL NOT CONTRADICT OR OTHERWISE ALTER THE
TERMS OF THIS AGREEMENT, INCLUDING, BUT NOT LIMITED TO, THE BELOW COST SHARING PROVISION. THE ARBITRATION SHALL BE BEFORE A SINGLE ARBITRATOR WHO SHALL BE A FORMER FEDERAL OR STATE COURT JUDGE. THE ARBITRATION SHALL APPLY THE FEDERAL RULES OF CIVIL
PROCEDURE, EXCEPT TO THE EXTENT SUCH RULES CONFLICT WITH THE JAMS RULES. EXECUTIVE UNDERSTANDS THAT THE PARTIES TO THE ARBITRATION SHALL EACH PAY AN EQUAL SHARE OF THE COSTS AND EXPENSES OF SUCH ARBITRATION (“ARBITRATION COSTS”), EXCEPT AS
PROHIBITED BY LAW, AND UNDERSTAND THAT EACH PARTY SHALL SEPARATELY PAY ITS RESPECTIVE ATTORNEYS’ FEES AND COSTS, UNLESS OTHERWISE ORDERED BY THE ARBITRATOR. EXECUTIVE AGREES THAT THE ARBITRATOR SHALL CONSIDER AND SHALL HAVE THE POWER TO DECIDE
ANY MOTIONS BROUGHT BY ANY PARTY TO THE ARBITRATION, INCLUDING MOTIONS FOR SUMMARY JUDGMENT AND/OR ADJUDICATION, AND MOTIONS TO DISMISS, PRIOR TO ANY ARBITRATION HEARING. EXECUTIVE AGREES THAT THE ARBITRATOR SHALL ISSUE A WRITTEN DECISION ON THE
MERITS. EXECUTIVE ALSO AGREES THAT THE ARBITRATOR SHALL HAVE THE POWER TO AWARD ANY REMEDIES AVAILABLE UNDER APPLICABLE LAW, INCLUDING MULTIPLE DAMAGES AND ATTORNEYS’ FEES. EXECUTIVE AGREES THAT THE DECREE OR AWARD RENDERED BY THE ARBITRATOR
MAY BE ENTERED AS A FINAL AND BINDING JUDGMENT IN ANY COURT HAVING JURISDICTION THEREOF. EXECUTIVE AGREES THAT THE ARBITRATOR SHALL APPLY SUBSTANTIVE MASSACHUSETTS LAW TO ANY DISPUTE OR CLAIM, WITHOUT REFERENCE TO RULES OF CONFLICT OF LAW. TO THE
EXTENT THAT THE JAMS RULES CONFLICT WITH SUBSTANTIVE MASSACHUSETTS LAW, MASSACHUSETTS LAW SHALL TAKE PRECEDENCE. EXECUTIVE AGREES THAT THE DECISION OF THE ARBITRATOR SHALL BE IN WRITING. EXECUTIVE AGREES THAT ARBITRATION UNDER THIS AGREEMENT SHALL
BE CONDUCTED IN MIDDLESEX COUNTY, MASSACHUSETTS. 
 c. Remedy. EXCEPT AS PROVIDED BY THE RULES AND THIS AGREEMENT, ARBITRATION SHALL
BE THE SOLE, EXCLUSIVE AND FINAL REMEDY FOR ANY DISPUTE BETWEEN EXECUTIVE AND THE COMPANY. ACCORDINGLY, EXCEPT AS PROVIDED FOR BY THE RULES AND THIS AGREEMENT, NEITHER EXECUTIVE NOR THE COMPANY WILL BE PERMITTED TO PURSUE COURT ACTION REGARDING
CLAIMS THAT ARE SUBJECT TO ARBITRATION. 

  
 13 

 d. Availability of Injunctive Relief. EXECUTIVE AGREES THAT ANY PARTY MAY ALSO
PETITION THE COURT FOR INJUNCTIVE RELIEF WHERE EITHER PARTY ALLEGES OR CLAIMS A VIOLATION OF THE AT-WILL EMPLOYMENT, CONFIDENTIAL INFORMATION, INVENTION ASSIGNMENT, AND ARBITRATION AGREEMENT BETWEEN EXECUTIVE
AND THE COMPANY OR ANY OTHER AGREEMENT REGARDING TRADE SECRETS, CONFIDENTIAL INFORMATION, NONCOMPETITION OR NONSOLICITATION. EXECUTIVE UNDERSTANDS THAT ANY BREACH OR THREATENED BREACH OF SUCH AN AGREEMENT WILL CAUSE IRREPARABLE INJURY AND THAT MONEY
DAMAGES WILL NOT PROVIDE AN ADEQUATE REMEDY THEREFOR AND BOTH PARTIES HEREBY CONSENT TO THE ISSUANCE OF AN INJUNCTION WITHOUT POSTING OF A BOND. 

e. Administrative Relief. EXECUTIVE UNDERSTANDS THAT THIS AGREEMENT DOES NOT PROHIBIT EXECUTIVE FROM PURSUING AN ADMINISTRATIVE CLAIM
WITH A LOCAL, STATE, OR FEDERAL ADMINISTRATIVE BODY OR GOVERNMENT AGENCY THAT IS AUTHORIZED TO ENFORCE OR ADMINISTER LAWS RELATED TO EMPLOYMENT, INCLUDING, BUT NOT LIMITED TO, THE MASSACHUSETTS COMMISSION AGAINST DISCRIMINATION, THE EQUAL EMPLOYMENT
OPPORTUNITY COMMISSION, THE NATIONAL LABOR RELATIONS BOARD, OR THE WORKERS’ COMPENSATION BOARD. THIS AGREEMENT DOES, HOWEVER, PRECLUDE EXECUTIVE FROM PURSUING COURT ACTION REGARDING ANY SUCH CLAIM, EXCEPT AS PERMITTED BY LAW. 

f. Voluntary Nature of Agreement. EXECUTIVE ACKNOWLEDGES AND AGREE THAT EXECUTIVE IS EXECUTING THIS AGREEMENT VOLUNTARILY AND WITHOUT
ANY DURESS OR UNDUE INFLUENCE BY THE COMPANY OR ANYONE ELSE. EXECUTIVE FURTHER ACKNOWLEDGES AND AGREES THAT EXECUTIVE HAS CAREFULLY READ THIS AGREEMENT AND THAT EXECUTIVE HAS ASKED ANY QUESTIONS NEEDED FOR EXECUTIVE TO UNDERSTAND THE TERMS,
CONSEQUENCES, AND BINDING EFFECT OF THIS AGREEMENT AND FULLY UNDERSTAND IT, INCLUDING THAT EXECUTIVE IS WAIVING EXECUTIVE’S RIGHT TO A JURY TRIAL. FINALLY, EXECUTIVE AGREES THAT EXECUTIVE HAS BEEN PROVIDED AN OPPORTUNITY TO SEEK THE ADVICE OF
AN ATTORNEY OF EXECUTIVE’S CHOICE BEFORE SIGNING THIS AGREEMENT. 
 9. Parachute Payments. 

a. Parachute Payments. Notwithstanding any other provisions of this Agreement, in the event that any payment or benefit by the Company
or otherwise to or for the benefit of Executive, whether paid or payable or distributed or distributable pursuant to the terms of this Agreement or otherwise (all such payments and benefits, including the payments and

  
 14 

 
benefits under Section 5(b)(i), Section 5(b)(ii), and Section 5(c) hereof, being hereinafter referred to as the “Total Payments”), would be subject (in whole or in part)
to the excise tax imposed by Section 4999 of the Code (the “Excise Tax”), then the Total Payments shall be reduced (in the order provided in this Section 9 below) to the minimum extent necessary to avoid the imposition of the
Excise Tax on the Total Payments, but only if (a) the net amount of such Total Payments, as so reduced (and after subtracting the net amount of federal, state and local income and employment taxes on such reduced Total Payments and after taking
into account the phase out of itemized deductions and personal exemptions attributable to such reduced Total Payments), is greater than or equal to (b) the net amount of such Total Payments without such reduction (but after subtracting the net
amount of federal, state and local income and employment taxes on such Total Payments and the amount of the Excise Tax to which Executive would be subject in respect of such unreduced Total Payments and after taking into account the phase out of
itemized deductions and personal exemptions attributable to such unreduced Total Payments). The Total Payments shall be reduced in the following order: (i) reduction on a pro-rata basis of any cash
severance payments that are exempt from Section 409A, (ii) reduction on a pro-rata basis any non-cash severance payments or benefits that are exempt from
Section 409A, (iii) reduction on a pro-rata basis of any other payments or benefits that are exempt from Section 409A, and (iv) reduction of any payments or benefits otherwise payable to
Executive on a pro-rata basis or such other manner that complies with Section 409A; provided, in case of clauses (ii), (iii) and (iv), that reduction of any payments attributable to the acceleration of
vesting of Company equity awards shall be first applied to Company equity awards that would otherwise vest last in time. All determinations regarding the application of this Section 9 shall be made by an accounting firm or consulting group with
experience in performing calculations regarding the applicability of Section 280G of the Code and the Excise Tax selected by the Company (the “Independent Advisors”). For purposes of determinations, no portion of the Total Payments
shall be taken into account which, in the opinion of the Independent Advisors, (x) does not constitute a “parachute payment” within the meaning of Section 280G(b)(2) of the Code (including by reason of Section 280G(b)(4)(A)
of 

  
 15 

 
the Code) or (y) constitutes reasonable compensation for services actually rendered, within the meaning of Section 280G(b)(4)(B) of the Code, in excess of the “base amount”
(as defined in Section 280G(b)(3) of the Code) allocable to such reasonable compensation. The costs of obtaining such determination and all related fees and expenses (including related fees and expenses incurred in any later audit) shall be
borne by the Company. In the event it is later determined that a greater reduction in the Total Payments should have been made to implement the objective and intent of this Section 9, the excess amount shall be returned immediately by Executive
to the Company. 
 10. Whistleblower Protections; Trade Secrets. Nothing in this Agreement, the Proprietary Agreement, Non-Compete Agreement or any other prior agreement between Executive and the Company (together, the “Subject Documents”) prevents Executive from reporting possible violations of law or regulation to any
governmental agency or entity in accordance with the provisions of and rules promulgated under Section 21F of the Securities Exchange Act of 1934 or Section 806 of the Sarbanes-Oxley Act of 2002, or any other whistleblower
protection provisions of state or federal law or regulation (including the right to receive an award for information provided to any such government agencies). Furthermore, in accordance with 18 U.S.C. § 1833, notwithstanding anything to the
contrary in any Subject Document: (a) Executive shall not be in breach of any Subject Document, and shall not be held criminally or civilly liable under any federal or state trade secret law (i) for the disclosure of a trade secret that is
made in confidence to a federal, state, or local government official or to an attorney solely for the purpose of reporting or investigating a suspected violation of law, or (ii) for the disclosure of a trade secret that is made in a complaint
or other document filed in a lawsuit or other proceeding, if such filing is made under seal; and (b) if Executive files a lawsuit for retaliation by the Company for reporting a suspected violation of law, Executive may disclose the trade secret
to Executive’s attorney, and may use the trade secret information in the court proceeding, if Executive files any document containing the trade secret under seal, and does not disclose the trade secret, except pursuant to court order. 

  
 16 

 11. General Provisions. 

a. Waiver. Either Party’s failure to enforce any provision of this Agreement shall not in any way be construed as a waiver of any
such provision, or prevent that Party thereafter from enforcing each and every other provision of this Agreement. 
 b. Severability.
In the event any provision of this Agreement is found to be unenforceable by a court of competent jurisdiction, such provision shall be deemed modified to the extent necessary to allow enforceability of the provision as so limited, it being intended
that the Parties shall receive the benefits contemplated in this Agreement to the fullest extent permitted by law. If a deemed modification is not satisfactory in the judgment of such arbitrator or court, the unenforceable provision shall be deemed
deleted, and the validity and enforceability of the remaining provisions shall not be affected. 
 c. Interpretation. The headings
set forth in this Agreement are for convenience only and shall not be used in interpreting this Agreement. 
 d. Notices. Except as
otherwise specifically provided herein, any notice required or permitted by this Agreement shall be in writing and shall be delivered as follows with notice deemed given as indicated: (i) by personal delivery when delivered personally;
(ii) by overnight courier upon written verification of receipt; (iii) by facsimile transmission upon acknowledgment of receipt of electronic transmission; or (iv) by certified or registered mail, return receipt requested, upon
verification of receipt. 
 e. Modifications and Amendments. This Agreement may be amended or modified only with the written consent
of the Executive and a duly authorized officer of the Company. No oral waiver, amendment or modification will be effective under any circumstances whatsoever. Notwithstanding anything herein to the contrary, to the extent that the Executive or the
Company reasonably believe that Section 409A of the Code will result in adverse tax consequences to the Executive as a result of this Agreement, then the Executive and the Company shall renegotiate this Agreement in good faith in order to
minimize or eliminate such tax consequences and retain the basic after-tax economics of this Agreement for the Executive to the extent possible. 

  
 17 

 f. Governing Law and Venue. This Agreement and the rights and obligations of the
Parties hereunder shall be construed in accordance with and governed by the law of Massachusetts without giving effect to the conflict of law principles thereof. 

g. Entire Agreement. This Agreement, together with the other agreements specifically referenced herein, including the Founder’s
RSA, the Non-Compete Agreement, and the Proprietary Agreement, embodies the entire agreement and understanding between the Parties hereto with respect to the subject matter hereof and supersedes all prior oral
or written agreements and understandings relating to the subject matter hereof, including the Prior Agreement. No statement, representation, warranty, covenant or agreement of any kind not expressly set forth in this Agreement shall affect, or be
used to interpret, change or restrict, the express terms and provisions of this Agreement. 
 h. Counterparts. This Agreement may be
executed in counterparts, each of which shall be original and all of which together shall constitute one and the same instrument. 
 i.
Company Representations. The Company represents and warrants that it is duly authorized to enter into this Agreement, that there is no law, agreement or other legal restriction on its entering into this Agreement, that its shareholders and
Board of Directors has approved this Agreement and that the officer signing this Agreement is duly authorized and empowered to sign this Agreement on behalf of the Company. 

THE PARTIES TO THIS AGREEMENT HAVE READ THIS AGREEMENT AND FULLY UNDERSTAND EACH AND EVERY PROVISION. 

  
 18 

 IN WITNESS WHEREOF, this Agreement has been executed by the Company, by its duly authorized
representative, and by the Executive, as of the date first above written. 
  

			
	FREQUENCY THERAPEUTICS, INC.

			
		
	By:	 	/s/ Marc A. Cohen

			
		
	Name:	 	MARC A. COHEN
		
	Title:	 	EXECUTIVE CHAIRMAN

  

	
	DAVID LUCCHINO
	
	/s/ David Lucchino
	Signature

  
 19

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