Document:

EX-10.1

 Exhibit 10.1 

EXECUTION COPY 
 SETTLEMENT
AGREEMENT AND GENERAL RELEASE 
 This Settlement Agreement and General Release (this “Agreement”) is entered into between
(a) GCA Savvian Advisors, LLC (“GCA Savvian” or “Plaintiff”), and (b) Violin Memory, Inc. (“Violin Memory” or “Defendant”) (collectively with Plaintiff, the “Parties”).1 Subject to the terms and conditions expressly provided herein, this Agreement is intended to fully, finally and forever compromise, settle, release, resolve, and dismiss with prejudice all claims
asserted in the Action. 
 WHEREAS: 

A. On or about September 21, 2010, the Parties executed an engagement letter (the “Engagement Letter”), pursuant to which GCA
Savvian would serve as Violin Memory’s financial advisor. 
 B. On August 23, 2012, GCA Savvian filed a one-count complaint for
breach of contract (the “GCA Savvian Action”) against Violin Memory in the Superior Court of the State of California, County of San Francisco, alleging that Violin Memory had not paid GCA Savvian fees that were allegedly owing under the
Engagement Letter. 
 C. On November 2, 2012, Violin Memory filed an answer and cross-complaint against GCA Savvian (the “Violin
Memory Action”). The cross-complaint brought claims against GCA Savvian for intentional fraud and deceit, constructive fraud, breach of fiduciary duty, negligent misrepresentation, breach of contract, and violation of the covenant of good faith
and fair dealing. 
 D. On August 26, 2013, GCA Savvian filed its First Amended Complaint (the “Complaint”), which is the
operative complaint in the Action. On October 2, 2013, Violin Memory served its answer to the Complaint. 
  

	1 	All terms with initial capitalization not otherwise defined herein shall have the meanings ascribed to them in ¶ 1 herein. 

 E. The Parties commenced discovery in 2013. The Parties exchanged thousands of documents during
the course of 2013 and conducted two depositions in 2014. 
 F. Beginning in February 2014, the Parties engaged in negotiations in an
attempt to resolve the Action. 
 G. This Agreement has been duly executed by the undersigned signatories and reflects the final and binding
agreement between the Parties. 
 H. This Agreement constitutes a compromise of matters that are in dispute between the Parties. The Parties
are entering into this Agreement solely to eliminate the uncertainty, burden and expense of further litigation. Each of the Parties has denied and continues to deny any wrongdoing, and this Agreement shall in no event be construed or deemed to be
evidence of or an admission or concession on the part of either of the Parties of their respective releasees with respect to any claim or allegation of any fault or liability or wrongdoing or damage whatsoever, or any infirmity in the defenses that
the Parties have, or could have, asserted. Violin Memory expressly denies that GCA Savvian has asserted any valid claims as to it, and expressly denies any and all allegations of fault, liability, wrongdoing or damages whatsoever. This Agreement
shall in no event be construed or deemed to be evidence of or an admission or concession on the part of GCA Savvian of any infirmity in any of the claims asserted in the GCA Savvian Action, or an admission or concession that any of Violin
Memory’s defenses to liability had any merit. Similarly, GCA Savvian expressly denies that Violin Memory has asserted any valid cross-claims as to it, and expressly denies any and all allegations of fault, liability, wrongdoing or damages
whatsoever. This Agreement shall in no event be construed or deemed to be evidence of or an admission or concession on the part of Violin Memory of any infirmity in any of the cross-claims asserted in the Violin Memory Action, or an admission or
concession that any of GCA Savvian’s 

  
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 defenses to liability had any merit. Each of the Parties recognizes and acknowledges, however, that the Action
has been initiated, filed, prosecuted and defended in good faith, and that the Action is being voluntarily settled with the advice of counsel. 

NOW THEREFORE, without any admission or concession by the Parties of any lack of merit of any claim, cross-claim, or defense in the Action,
and without any admission or concession of any liability or wrongdoing, it is hereby AGREED, by and among the Parties, that in consideration of the benefits flowing to the Parties from the Settlement, all Released Plaintiff’s Claims as against
the Violin Memory Releasees, and all Released Defendant’s Claims as against the GCA Savvian Releasees, shall be fully, finally and forever compromised, settled, released, discharged and dismissed with prejudice, upon and subject to the terms
and conditions set forth below. 
 DEFINITIONS 

1. As used in this Agreement, the following capitalized terms shall have the following meanings: 

(a) “Action” means the GCA Savvian Action and the Violin Memory Action, captioned GCA Savvian Advisors, LLC v.
Violin Memory, Inc., No. CGC 12-523598, in the Superior Court of the State of California, County of San Francisco. 
 (b)
“Cash Settlement Amount” means the amount of $2,000,000 in cash. 
 (c) “Court” means the Superior Court
of the State of California, County of San Francisco. 
 (d) “Effective Date” means the date of the execution of
this Agreement by the last to sign of Violin Memory and GCA Savvian. 

  
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 (e) “Exchange Act” means the Securities Exchange Act of 1934, as
amended, and the rules and regulations thereunder, or any successor statute or rules and regulations. 
 (f) “GCA
Savvian Releasees” means (i) GCA Savvian; (ii) each of the respective past or present parents, subsidiaries, affiliates, successors and predecessors of GCA Savvian; and (iii) the respective officers, directors, agents, employees,
attorneys, advisors, investment advisors, auditors, accountants, insurers, and assigns of the foregoing in (i) and (ii), in their capacities as such. 

(g) “Released Claims” means all Released Plaintiff’s Claims and all Released Defendant’s Claims. 

(h) “Released Defendant’s Claims” means all claims, debts, demands, rights or causes of action or liabilities
whatsoever (including, but not limited to, any claims for damages, interest, attorneys’ fees, expert or consulting fees, and any other costs, expenses or liabilities), whether known claims or Unknown Claims, whether arising under federal,
state, local, statutory, common or foreign law, or any other law, rule or regulation, whether fixed or contingent, accrued or un-accrued, liquidated or un-liquidated, at law or in equity, matured or un-matured, whether class or individual in nature,
that Violin Memory has asserted in this Action or could have asserted in any forum, whether as a claim, defense, cross-claim, or otherwise. 

(i) “Released Plaintiff’s Claims” means all claims, debts, demands, rights or causes of action or liabilities
whatsoever (including, but not limited to, any claims for damages, interest, attorneys’ fees, expert or consulting fees, and any other costs, expenses or liabilities), whether known claims or Unknown Claims, whether arising under federal,
state, 

  
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local, statutory common or foreign law, or any other law, rule or regulation, whether fixed or contingent, accrued or un-accrued, liquidated or un-liquidated, at law or in equity, matured or
un-matured, whether class or individual in nature, that GCA Savvian asserted in the Action or could have asserted in any forum, whether as a claim, defense, cross-claim, or otherwise, including without limitation those related to the issuance of the
Stock Settlement Amount. 
 (j) “Releasee(s)” means each and any of the GCA Savvian Releasees and each and any of
the Violin Memory Releasees. 
 (k) “Releases” means the releases set forth in ¶¶ 3-4 of this Agreement.

 (l) “Rule 144” means Rule 144 adopted by the SEC under the Securities Act, 17 C.F.R. § 230.144. 

(m) “SEC” means the United States Securities and Exchange Commission. 

(n) “Securities Act” means the Securities Act of 1933, as amended, and the rules and regulations thereunder, or any
successor statute or rules and regulations. 
 (o) “Settlement” means the resolution of the Action in accordance
with the terms and provisions of this Agreement. 
 (p) “Settlement Amount” means the Cash Settlement Amount and
the Stock Settlement Amount. 
 (q) “Stock Settlement Amount” means the number of duly authorized, validly issued
and fully paid and non-assessable shares of Violin Memory common stock, par value $0.0001 per share, calculated in the manner prescribed in ¶ 8 below. 

(r) “Unknown Claims” means any Released Plaintiff’s Claims which any GCA Savvian Releasee does not know or
suspect to exist in his, her or its favor at the time of the release of such claims, and any Released Defendant’s Claims which any Violin Memory 

  
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 Releasee does not know or suspect to exist in his, her, or its favor at the time of the release
of such claims, which, if known by him, her or it, might have affected his, her or its decision(s) with respect to this Settlement. 

(s) “Violin Memory Releasees” means (i) Violin Memory; (ii) each of the respective past or present parents,
subsidiaries, affiliates, successors and predecessors of Violin Memory; and (iii) the respective past or present officers, directors, agents, employees, attorneys, advisors, investment advisors, auditors, accountants, insurers and assigns, of
the foregoing in (i) and (ii) in their capacities as such. Notwithstanding the foregoing, Violin Memory Releasees does not include GCA Savvian. 

RELEASE OF CLAIMS 
 2. The
obligations incurred pursuant to this Agreement are in consideration of the full and final disposition of the Action between the Parties and the Releases provided for herein. 

3. Upon the Effective Date, without further action by anyone, the GCA Savvian Releasees shall have fully, finally and forever compromised,
settled, released, resolved, relinquished, waived and discharged each and every Released Plaintiff’s Claim against the Violin Memory Releasees and shall forever be enjoined from prosecuting any or all of the Released Plaintiff’s Claims
against any of the Violin Memory Releasees. 
 4. Upon the Effective Date, without further action by anyone, the Violin Memory Releasees
shall have fully, finally and forever compromised, settled, released, resolved, relinquished, waived and discharged each and every Released Defendant’s Claim against the GCA Savvian Releasees, and shall forever be enjoined from prosecuting any
or all of the Released Defendant’s Claims against any of the GCA Savvian Releasees. 

  
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 5. The Parties, having been advised by counsel, acknowledge that they are familiar with the
provisions of Section 1542 of the California Civil Code, which provides as follows: 
 A GENERAL RELEASE DOES NOT EXTEND TO CLAIMS
WHICH THE CREDITOR DOES NOT KNOW OR SUSPECT TO EXIST IN HIS OR HER FAVOR AT THE TIME OF EXECUTING THE RELEASE, WHICH IF KNOWN BY HIM OR HER MUST HAVE MATERIALLY AFFECTED HIS OR HER SETTLEMENT WITH THE DEBTOR. 

The Parties expressly waive and relinquish, to the fullest extent permitted by law, all rights and benefits under Section 1542 of the California
Civil Code, and any law or legal principle of similar effect in any jurisdiction, whether federal or state, with respect to the releases and/or discharges granted in this Agreement. The Parties fully understand that the facts upon which this
Agreement is executed may hereafter be other than or different from the facts now believed by the Parties and/or their counsel to be true and expressly accept and assume the risk of such possible difference in facts and agree that this Agreement
shall remain effective notwithstanding any such difference in facts. The Parties acknowledge and agree that the Parties’ respective waivers pursuant to this Paragraph is an essential and material term of this Agreement and the Settlement that
underlies it and that without such waivers the Settlement would not have been accepted. 
 6. Notwithstanding ¶¶ 3-5
above, nothing in this Agreement shall bar any action by the Parties to enforce or effectuate the terms of this Agreement. 

  
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 THE SETTLEMENT CONSIDERATION 

7. In consideration of the settlement of the Released Plaintiff’s Claims against the Violin Memory Releasees, and the settlement of the
Released Defendant’s Claims against the GCA Savvian Releasees, Violin Memory agrees to do the following: 
 (a) No later
than five (5) business days after this Agreement’s Effective Date, Violin Memory shall pay the Cash Settlement Amount to GCA Savvian by wire transfer based on wire instructions to be provided by GCA Savvian. 

(b) No later than five (5) business days after this Agreement’s Effective Date, Violin Memory shall issue to GCA
Savvian through a private placement the number of shares representing the Stock Settlement Amount, which will be issued in an uncertificated form on the books of Violin Memory’s transfer agent. 

8. The Stock Settlement Amount shall be the number of shares of Violin Memory common stock equal to $500,000, based on the average of the
closing bid price of Violin Memory common stock for the five (5) days prior to the Effective Date, rounded to the nearest whole share and reduced, if necessary, so that the number of shares does not exceed 19.9% of all outstanding Violin Memory
common stock on such date. 
 9. Violin Memory represents and warrants that it is, and has been for more than 90 days, subject to the
reporting requirements of section 13 or 15(d) of the Exchange Act. 
 10. With a view to making available to GCA Savvian the benefits of
Rule 144, Violin Memory agrees to: (a) make and keep public information available, as those terms are understood and defined in Rule 144; (b) file with the SEC in a timely manner all reports and other documents required of Violin Memory
under the Securities Act and the Exchange Act so long as it remains subject to such requirements and the filing of such reports and other documents is required for the applicable provisions of Rule 144; and (c) furnish to CGA Savvian so long as
it owns shares constituting the Stock Settlement Amount, promptly upon request, (i) a written statement by Violin Memory, if true, that to the best of its knowledge, it has complied with the reporting, submission and posting requirements of
Rule 144 and the Exchange Act, and (ii) such other information as may be reasonably requested to permit GCA Savvian to sell such securities pursuant to Rule 144 without registration. 

  
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 11. GCA Savvian hereby expressly acknowledges that (a) the Stock Settlement Amount is an
expressly bargained-for and material term of this Agreement; (b) the Stock Settlement Amount entails economic and other risks; and (c) Violin Memory makes no representations about the future performance of any Violin Memory common stock
issued pursuant to this Agreement. GCA Savvian represents and warrants that it is familiar with the risks inherent in stock ownership; has evaluated and been advised as to those risks; has reviewed Violin Memory’s filings made with the SEC
pursuant to the Exchange Act; has had an opportunity to ask Violin Memory such questions as it deems appropriate about the stock constituting the Stock Settlement Amount; and is entering into this Agreement expressly assuming all such risks. 

12. Within three (3) business days of the later of GCA Savvian’s receipt of the Cash Settlement Amount or GCA Savvian’s receipt
of the Stock Settlement Amount, the Parties shall execute and file with the Court a stipulation of dismissal with prejudice of all claims, cross-claims, and defenses pleaded by each Party in the Action, with each Party to bear its own
attorneys’ fees and costs incurred in the Action. The Parties shall take any further actions reasonably necessary to ensure that the Court enters an order of dismissal. 

PLACEMENT AND REMOVAL OF LEGENDS 

13. GCA Savvian hereby expressly acknowledges that the Stock Settlement Amount will bear a restrictive private placement legend substantially
in the following form: 
 THE SECURITIES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS
AMENDED (THE “SECURITIES ACT”), AND MAY NOT BE SOLD OR TRANSFERRED IN THE ABSENCE OF AN EFFECTIVE REGISTRATION STATEMENT UNDER THE SECURITIES ACT OR AN EXEMPTION FROM REGISTRATION THEREUNDER. 

  
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 14. Violin Memory agrees that, subject to applicable law, it shall remove the restrictive private
placement legend from the stock delivered to GCA Savvian pursuant to ¶ 7(b) if at the time GCA Savvian requests such removal, GCA Savvian provides a shareholder representation letter and, if applicable, broker letter, addressed to Violin Memory
and its transfer agent covering customary factual matters establishing the availability of Rule 144 for proposed resales, which may include (a) a representation and acknowledgement that GCA Savvian has held the restricted securities for at
least six months and has not transferred, directly or indirectly, the economic consequence of ownership during such period and (b) a representation and acknowledgement that GCA Savvian is not – and has not been for at least 90 days –
an affiliate of Violin Memory as that term is defined in Rule 405 of the Securities Act and as that term has been interpreted by the SEC. Within five (5) business days of receiving the required representations from GCA Savvian, Violin Memory
shall arrange for the removal of the private placement restrictive legend. 
 NO ADMISSION OF WRONGDOING 

15. Whether or not the Settlement is consummated, this Agreement, the negotiations leading to the execution of this Agreement, and any
proceedings taken pursuant to or in connection with this Agreement shall not be offered against any of the Releasees as evidence of, or construed as, or deemed to be evidence of any presumption, concession, or admission with respect to the truth of
any fact alleged, or the validity of any claim or cross-claim that was or could have been asserted, or the deficiency of any defense that has been or could have been asserted in this Action or in any other litigation, or of any liability,
negligence, fault, or other wrongdoing of any kind, in any civil, criminal or administrative action or proceeding, other than such proceedings as may be necessary to effectuate the provisions of this Agreement. 

  
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 MISCELLANEOUS PROVISIONS 

16. Subject to the provisions of ¶ 19 below, the terms of the Settlement, as reflected in this Agreement, may not be modified or
amended, nor may any of its provisions be waived, except by a writing signed on behalf of both GCA Savvian and Violin Memory (or their successors-in-interest). The Parties expressly agree that the provisions of California Civil Code § 1698
do not apply and that the terms of this Agreement may not be modified by the Parties’ course of performance or otherwise, except in accordance with this ¶ 16. 

17. The headings herein are used for the purpose of convenience only and are not meant to have legal effect. 

18. The administration and consummation of the Settlement as embodied in this Agreement shall be under the authority of the Court, and the
Court shall retain jurisdiction for the purpose of enforcing the terms of the Settlement. 
 19. Any condition in this Agreement may be
waived by the party entitled to enforce the condition in a writing signed by that party or its counsel. The waiver of any breach of this Agreement shall not be deemed a waiver of any other prior or subsequent breach of this Agreement. The Parties
may agree to reasonable extensions of time to carry out any of the provisions of this Agreement. 
 20. This Agreement constitutes the
entire agreement among the Parties concerning the Settlement. The Parties acknowledge that no other agreements, representations, warranties, or inducements have been made by any Party hereto concerning this Agreement other than those contained and
memorialized herein. 
 21. This Agreement may be executed in one or more counterparts, including by signature transmitted via facsimile or
by a .pdf/.tif image of the signature transmitted via email. All executed counterparts and each of them shall be deemed to be one and the same instrument. 

  
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 22. This Agreement shall be binding upon and inure to the benefit of the successors and assigns
of the Parties, including any and all Releasees and any corporation, partnership, or other entity into or with which any Party hereto may merge, consolidate or reorganize. 

23. The construction, interpretation, operation, effect and validity of this Agreement and all documents necessary to effectuate it shall be
governed by the internal laws of the State of California without regard to conflicts of laws, except to the extent that federal law requires that federal law govern. 

24. Any action arising under or to enforce this Agreement or any portion thereof, shall be commenced only in the Court, unless such action is
required to be brought in Federal court, in which case such action shall be commenced in the United States District Court for the Northern District of California. 

25. This Agreement shall not be construed more strictly against one Party than another merely by virtue of the fact that it, or any part of
it, may have been prepared by counsel for one of the Parties. This Agreement is the result of arm’s-length negotiations between the Parties and both Parties have contributed substantially and materially to the preparation of this Agreement.

 26. All persons executing this Agreement, or any related documents, warrant and represent that they have the full authority to do so and
that they have the authority to take appropriate action required or permitted to be taken pursuant to this Agreement to effectuate its terms. 

27. Each of the Parties has been advised by their respective counsel as to the terms of this Agreement. Neither Violin Memory nor Violin
Memory’s representatives, agents or attorneys has provided any advice or recommendations to GCA Savvian, including without limitation regarding the Stock Settlement Amount. GCA Savvian hereby expressly disclaims reliance on any

  
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representations made by Violin Memory or Violin Memory’s representatives, agents or attorneys with respect to this Agreement and the Stock Settlement Amount provided for herein. Similarly,
neither GCA Savvian nor GCA Savvian’s representatives, agents or attorneys has provided any advice or recommendations to Violin Memory, including without limitation regarding the Stock Settlement Amount. Violin Memory hereby expressly disclaims
reliance on any representations made by GCA Savvian or GCA Savvian’s representatives, agents or attorneys with respect to this Agreement and the Stock Settlement Amount provided for herein. 

28. Each Party shall bear its own costs and attorneys’ fees. 

29. Each Party shall be solely responsible for bearing its own tax liability, if any, relating to the Settlement Amount. Neither Party has
made any representations to the other, and neither Party is relying on any representations of the other, with respect to any potential tax liability. 

30. The Parties may disclose the terms and conditions of this Agreement to non-Parties in the following circumstances: (i) to the extent
necessary to enforce or comply with the provisions hereof or to comply with any insurance requirements; (ii) to the extent necessary to comply with any state or federal law, rule or regulation, or self-regulatory organization rule or
regulation; (iii) to the extent required by law or by judicial or administrative process, including a lawfully issued subpoena; and (iv) to the extent necessary in the ordinary course of business. Whether such circumstances exist shall be
determined from the perspective of a reasonable person in the disclosing Party’s position. If a Party is (a) subpoenaed in another action, (b) served with a demand or request in another action to which it is a party, or
(c) served with any legal process by any person or entity who is not a party to this Agreement, seeking information or documents regarding this Agreement, that Party shall notify the other Party of the request, demand, or

  
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subpoena as soon as practicable after receipt of the request, demand, or subpoena (and, at a minimum, fourteen (14) calendar days before a response is due) so as to allow the other Party to
seek protection from the relevant court(s), agency, or tribunal. In other circumstances not enumerated above, the Parties and their counsel and agents will not disclose the terms and conditions of this Agreement, but they may state without further
comment or characterization that the case has been settled to the Parties’ satisfaction. The Parties will not disclose the negotiations leading to this Agreement and will not issue press releases or use other means to publicize this Agreement.

 31. The Parties and their counsel agree that ¶ 30 is a material consideration for the Parties entering into this Agreement. However,
a breach of this provision shall not affect the continuing validity and effectiveness of the releases granted herein. 
 32. All agreements
made and orders entered during the course of this Action relating to the confidentiality of information, including without limitation the Stipulated Protective Order entered by the Court on April 16, 2013, shall survive this Settlement. 

33. Within three (3) business days of the entry of an order dismissing the Action, each Party shall inform any person or entity upon whom
it has served a third-party subpoena that the Action has been terminated and the subpoena withdrawn. 

  
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 IN WITNESS WHEREOF, the parties hereto have caused this Agreement to be executed as of the
dates indicated below. 
  

							
	 DATE: August 6, 2014
	 		 	GCA SAVVIAN ADVISORS, LLC
				
		 		 	By:	 	
			
		 		 	 /s/ Mark J. McInerney

		 		 	Signature
			
		 		 	 Mark J. McInerney

		 		 	Name
			
		 		 	 Managing Director

		 		 	Title
			
	 DATE: August 4, 2014
	 		 	VIOLIN MEMORY, INC.
				
		 		 	By:	 	
			
		 		 	 /s/ Gary Lloyd

		 		 	Signature
			
		 		 	 Gary Lloyd

		 		 	Name
			
		 		 	 Vice President, General Counsel & Secretary

		 		 	Title

  
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	Approved as to Form:	 		 		 	
				
	 /s/ Matthew D. Brown
	 		 		 	 /s/ Orin Snyder

	Matthew D. Brown	 		 		 	Orin Snyder
	Gordon C. Atkinson	 		 		 	Goutam U. Jois
	Laura Elliott	 		 		 	GIBSON, DUNN & CRUTCHER LLP
	COOLEY LLP	 		 		 	200 Park Avenue
	101 California Street, Fifth Floor	 		 		 	New York, NY 10166
	San Francisco, CA 94111-5800	 		 		 	(212) 351-4000
	(415) 693-2000	 		 		 	(212) 351-4035 fax
	(415) 693-2222 fax	 		 		 	
				
		 		 		 	Vanessa A. Pastora
	Counsel for GCA Savvian Advisors, LLC	 		 		 	GIBSON, DUNN & CRUTCHER LLP
		 		 		 	555 Mission Street
		 		 		 	San Francisco, CA 94105-0921
		 		 		 	(415) 393-8200
		 		 		 	(415) 393-8306 fax
				
		 		 		 	Counsel for Violin Memory, Inc.

  
 16EX-10.1

 Exhibit 10.1 

KERYX BIOPHARMACEUTICALS, INC. 

THIRD AMENDED AND RESTATED DIRECTORS EQUITY COMPENSATION PLAN 

 KERYX BIOPHARMACEUTICALS, INC. 

THIRD AMENDED AND RESTATED DIRECTORS EQUITY COMPENSATION PLAN 

ARTICLE 1 
 PURPOSE

 1.1. PURPOSE. The purpose of the Keryx Biopharmaceuticals, Inc. Third Amended and Restated Directors Equity
Compensation Plan is to attract, retain and compensate highly-qualified individuals who are not employees of Keryx Biopharmaceuticals, Inc. or any of its subsidiaries or affiliates for service as members of the Board by providing them with an
opportunity to participate in the Company’s future growth through the granting of stock-based incentive awards. The Company intends that the Plan will benefit the Company and its stockholders by allowing Non-Employee Directors to have a
personal financial stake in the Company through an ownership interest in the Common Stock and will closely associate the interests of Non-Employee Directors with that of the Company’s stockholders. 

1.2. ELIGIBILITY. All active Non-Employee Directors shall automatically be participants in the Plan. 

ARTICLE 2 
 DEFINITIONS

 2.1. DEFINITIONS. Capitalized terms used herein and not otherwise defined shall have the meanings given such terms in
the LTIP. Unless the context clearly indicates otherwise, the following terms shall have the following meanings: 
 (a) “Award”
means any Option or Restricted Stock Award granted to a Non-Employee Director under Article 5 of the Plan. 
 (b) “Award
Certificate” means a written document, in such form as the Board prescribes from time to time, setting forth the terms and conditions of the Award. 

(c) “Board” means the Board of Directors of the Company. 

(d) “Code” means the Internal Revenue Code of 1986, as amended from time to time. 

(e) “Company” means Keryx Biopharmaceuticals, Inc., a Delaware corporation. 

(f) “Common Stock” means the common stock, $0.001 par value, of the Company. 

(g) “Disability” has the same meaning as provided in the long-term disability plan or policy maintained by the Company or if
applicable, most recently maintained, by the Company, whether or not such Grantee actually receives disability benefits under such plan or policy. If no long-term disability plan or policy was ever maintained on behalf of Grantee, Disability means
Permanent and Total Disability as defined in Section 22(e)(3) of the Code. In the event of a dispute, the determination whether a Grantee is Disabled will be made by the Board and may be supported by the advice of a physician competent in the
area to which such Disability relates. 

 (h) “Grantee” means a Non-Employee Director of the Company to whom an Award has been
granted under Article 5. 
 (i) “LTIP” means the Keryx Biopharmaceuticals, Inc. 2013 Incentive Plan, or any subsequent equity
compensation plan approved by the Board and designated as the LTIP for purposes of this Plan. 
 (j) “Non-Employee Director” means
a director of the Company who is not an employee of the Company or any of its Subsidiaries or Affiliates. 
 (k) “Option” means an
option to purchase Common Stock granted under Article 5 of the Plan. Options granted under the Plan are not incentive stock options within the meaning of Section 422 of the Code. 

(l) “Plan” means the Keryx Biopharmaceuticals, Inc. Second Amended and Restated Directors Equity Compensation Plan, as amended from
time to time. 
 (m) “Restricted Stock” means Common Stock granted under Article 5 of the Plan that is subject to certain
restrictions and to risk of forfeiture. 
 (n) “Retirement” means retirement as a director of the Company in accordance with
normal Company policies. 
 ARTICLE 3 

ADMINISTRATION 
 3.1.
ADMINISTRATION. The Plan shall be administered by the Board. Subject to the provisions of the Plan, the Board shall be authorized to interpret the Plan, to establish, amend and rescind any rules and regulations relating to the Plan,
and to make all other determinations necessary or advisable for the administration of the Plan. The Board’s interpretation of the Plan, and all actions taken and determinations made by the Board pursuant to the powers vested in it hereunder,
shall be conclusive and binding upon all parties concerned including the Company, its stockholders and persons granted awards under the Plan. Notwithstanding the above, the selection of the directors to whom Awards are to be granted, the timing of
such grants, the number of shares subject to such grant, the exercise price of any Option, the periods during which any Option may be exercised or any Restricted Stock vests, and the term of any Award shall be as hereinafter provided, and the Board
shall have no discretion as to such matters. The Board may appoint a plan administrator to carry out the ministerial functions of the Plan, but the administrator shall have no other authority or powers of the Board. 

3.2. RELIANCE. In administering the Plan, the Board may rely upon any information furnished by the Company, its public accountants and
other experts. No individual will have personal liability by reason of anything done or omitted to be done by the Company or the Board in connection with the Plan. 

3.3. INDEMNIFICATION. Each person who is or has been a member of the Board or who otherwise participates in the administration or
operation of the Plan shall be indemnified by the Company against, and held harmless from, any loss, cost, liability or expense that may be imposed upon or incurred by him or her in connection with or resulting from any claim, action, suit or
proceeding in which such person may be involved by reason of any action taken or failure to act under the Plan and shall be fully 

  
 – 2 – 

 
reimbursed by the Company for any and all amounts paid by such person in satisfaction of judgment against him or her in any such action, suit or proceeding, provided he or she will give the
Company an opportunity, by written notice to the Board, to defend the same at the Company’s own expense before he or she undertakes to defend it on his or her own behalf. This right of indemnification shall not be exclusive of any other rights
of indemnification. 
 ARTICLE 4 

SHARES 
 4.1. SOURCE OF
SHARES FOR THE PLAN. The Awards and shares of Common Stock that may be issued pursuant to the Plan shall be issued under the LTIP, subject to all of the terms and conditions of the LTIP. The terms contained in the LTIP are incorporated
into and made a part of this Plan with respect to Awards granted pursuant hereto and any such Awards shall be governed by and construed in accordance with the LTIP. In the event of any actual or alleged conflict between the provisions of the LTIP
and the provisions of this Plan, the provisions of the LTIP shall be controlling and determinative. This Plan does not constitute a separate source of shares for the grant of the Awards provided herein. 

ARTICLE 5 
 EQUITY AWARDS

 5.1 INITIAL OPTION AWARD. Subject to share availability under the LTIP, on the first date a Non-Employee Director is initially
elected or appointed to the Board, he or she shall receive an Option to purchase 50,000 shares of Common Stock. Such Option shall vest and become exercisable as to one-third of the Option on each of the first three anniversaries of the date of grant
of the Option. Such Option shall be subject to the terms and restrictions described below in this Article 5. 
 5.2 ANNUAL OPTION
AWARD. Effective as of the 2014 annual meeting and subject to share availability under the LTIP, on the day following each annual meeting of the Company’s stockholders, each Non-Employee Director serving as such on that date (other than a
director who first became a Non-Employee Director at the stockholders meeting held on the previous day) shall be granted an Option to purchase 30,000 shares of Common Stock. Such Option shall vest and become exercisable as to one-third of the Option
on each of the first three anniversaries of the date of grant of the Option. Such Option shall be subject to the terms and restrictions described below in this Article 5, and shall be in addition to any otherwise applicable annual grant of
Restricted Stock granted to such Non-Employee Director under Section 5.3. 
 5.3 ANNUAL RESTRICTED STOCK AWARD. Effective as of
the 2014 annual meeting and subject to share availability under the LTIP, on the day following each annual meeting of the Company’s stockholders, each Non-Employee Director serving as such on that date (other than a director who first became a
Non-Employee Director at the stockholders meeting held on the previous day) shall be granted 10,000 shares of Restricted Stock. Such Restricted Stock shall vest and become non-forfeitable as to one-third of the shares on each of the first three
anniversaries of the date of grant of the Restricted Stock. Such Restricted Stock shall be subject to the terms and restrictions described below in this Article 5, and shall be in addition to any otherwise applicable annual grant of Options granted
to such Non-Employee Director under Section 5.2. 

  
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 5.4 TERMS AND CONDITIONS OF AWARDS. Awards granted under this Article 5 shall be subject
to the terms and conditions described below and in the LTIP. 
 (a) Vesting. Each Award granted under this Plan shall vest as
provided in Sections 5.1, 5.2 and 5.3 above, respectively; provided, however, that each Award shall become fully vested upon the occurrence of a Change of Control. 

(b) Exercise Price of Options. The exercise price per Share under an Option shall be equal to Fair Market Value of the underlying
Common Stock on the date of grant. 
 (c) Effect of Termination of Directorship. 

(i) Options. Upon termination of a Grantee’s membership on the Board for any reason other than for cause (including
without limitation, by reason of death, Disability, Retirement or failure to be re-nominated or re-elected as a director), (i) the Grantee’s Options, to the extent they were exercisable on the date of termination, shall remain exercisable
until the first anniversary of the Grantee’s termination as a director, and (ii) the Grantee’s Options that were not exercisable on the date of termination shall expire upon the date of such termination. In the event of the death of a
Grantee, the Grantee’s personal representatives, heirs or legatees may exercise the Options held by the Grantee on the date of death, upon proof satisfactory to the Company of their authority. Such exercise otherwise shall be subject to the
terms and conditions of the Plan. If a Grantee’s membership on the Board is terminated for cause, all of such Grantee’s Options, whether vested or unvested, shall expire upon the date of such termination. 

(ii) Restricted Stock. Upon termination of a Grantee’s membership on the Board for any reason (including without
limitation, by reason of death, Disability, Retirement or failure to be re-nominated or re-elected as a director), the Grantee shall forfeit all of his or her right, title and interest in and to any unvested shares of Restricted Stock as of the date
of such termination from the Board and such Restricted Stock shall be reconveyed to the Company without further consideration or any act or action by the Grantee. 

(d) Transferability of Awards. No right or interest of a Grantee in any Award may be pledged, encumbered, or hypothecated to or in
favor of any party other than the Company or an affiliate, or shall be subject to any lien, obligation, or liability of such Grantee to any other party other than the Company, an affiliate, or a member of the Grantee’s immediate family, a trust
for the benefit of the Grantee or such family members, or a partnership or other entities in which the Grantee and such family members are the only partners, stockholders, or owners (each a “Permitted Transferee”). Unless otherwise
specifically provided in an Award Certificate, no Award shall be assignable or transferable by a Grantee other than (a) by will or the laws of descent and distribution, or (b) pursuant to a domestic relations order that would satisfy
Section 414(p)(1)(A) of the Code if such Section applied to an Award under the Plan, or (c) except in the case of an Award for which such transferability would result in accelerated taxation, to a Permitted Transferee. 

(e) Rights as Stockholder. No Option gives a Grantee any of the rights of a stockholder of the Company unless and until shares of
Common Stock are in fact issued to such person in connection with such Option. The Grantee shall have all of the rights of a stockholder with respect to the Restricted Stock. 

  
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 (f) No Awards after Ten Years. No Award shall be granted except within a period of ten
(10) years after the effective date of the Plan. 
 (g) Award Certificates. All Awards shall be evidenced by a written Award
Certificate between the Company and the Non-Employee Director, which shall include such provisions, not inconsistent with the Plan or the LTIP, as may be specified by the Board. 

5.5 ADJUSTMENTS. The adjustment provisions of the LTIP shall apply with respect to Awards granted pursuant to this Plan. Without
limiting the foregoing, in the event of a subdivision of the outstanding Common Stock (stock-split), a declaration of a dividend payable in shares of Common Stock, or a combination or consolidation of the outstanding Common Stock into a lesser
number of shares of Common Stock, the number of Awards to be granted to Grantees in accordance with Article 5 hereof shall be adjusted proportionately and the shares of Common Stock then subject to each Award shall automatically be adjusted
proportionately without any change in the aggregate purchase price therefore. 
 ARTICLE 6 

AMENDMENT, MODIFICATION AND TERMINATION 

6.1. AMENDMENT, MODIFICATION AND TERMINATION. The Board may, at any time and from time to time, amend, modify or terminate the Plan
without stockholder approval; provided, however, that if an amendment to the Plan would, in the reasonable opinion of the Board, require stockholder approval under applicable laws, policies or regulations or the applicable listing or other
requirements of a securities exchange on which the Common Stock is listed or traded, then such amendment shall be subject to stockholder approval; and provided further, that the Board may condition any other amendment or modification on the approval
of stockholders of the Company for any reason. 
 ARTICLE 7 

GENERAL PROVISIONS 
 7.1.
EXPENSES OF THE PLAN. The expenses of administering the Plan shall be borne by the Company. 
 7.2. EFFECTIVE DATE AND
DURATION OF THE PLAN. The Plan shall be effective as of the date it is approved by the Board. The Plan shall remain in effect until terminated by the Board. The Plan was originally adopted by the Board on March 7, 2005. The first amended
and restated Plan was adopted by the Board on September 19, 2006, and subsequently amended on September 20, 2007. The Second Amended and Restated Plan was adopted by the Board of Directors on June 15, 2010. The Third Amended and
Restated Plan was adopted by the Board of Directors on June 23, 2014. 
  

			
	KERYX BIOPHARMACEUTICALS, INC.
		
	By:	 	 /s/ Ron Bentsur

  
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