Document:

Amendment No. 2 to Rights Agreement, dated as of August 28, 2007

    Exhibit
      4.1.1

     

    CYTORI
      THERAPEUTICS, INC.

     

    AMENDMENT
      NO. 2 TO RIGHTS AGREEMENT

     

    This
      Amendment No. 2 To Rights Agreement
      (this
“Amendment”)
      is
      made as of August 28, 2007 between Cytori
      Therapeutics, Inc. (formerly
      known as
      MacroPore Biosurgery, Inc.),
      a
      Delaware corporation (the “Corporation”),
      and
Computershare
      Trust Company, N.A.
      (as
      successor to
      Computershare Trust Company, Inc.),
      a
      Colorado Corporation (the “Rights
      Agent”).
      

     

    Whereas,
      the
      Corporation and the Rights Agent entered into that certain Rights Agreement
      dated as of May 29, 2003 (the “Rights
      Agreement”)
      (capitalized terms used in this Agreement but not defined herein shall have
      the
      meaning assigned to them in the Rights Agreement); and

     

    Whereas,
      the
      Corporation and the Rights Agent entered into that certain Amendment No. 1
      to
      Rights Agreement dated as of May 12, 2005 (the “Amendment
      No. 1”);
      and

     

    Whereas,
      the
      Corporation and the Rights Agent desire to irrevocably amend the Rights
      Agreement as provided below.

     

    Now,
      Therefore,
      in
      consideration of the foregoing premises and the mutual covenants and conditions
      set forth below, and for other good and valuable consideration, the receipt
      of
      which is hereby acknowledged, the parties to this Amendment No. 2 to Rights
      Agreement hereby agree as follows:

     

     

    AMENDMENT

     

    1.  Amendment
      of the Rights Agreement. 

     

    1.1  Preamble.
      The
      preamble of the Rights Agreement is hereby amended to reflect the name of the
      Corporation as, “Cytori Therapeutics, Inc. (formerly known as MacroPore
      Biosurgery, Inc.),” and the name of the Rights Agent as, “Computershare Trust
      Company, N.A. (as successor to Computershare Trust Company, Inc.).”

     

    1.2  Section
      1.10.
      Section
      1.10 of the Rights Agreement is hereby amended in its entirety, to read:

     

    ““Close
      of Business” on any given date means 5:00 P.M., Eastern time, on such date;
      provided, however, that if such date is not a Business Day it means 5:00 P.M.,
      Eastern time, on the next succeeding Business Day.”

     

    1.3  Section
      2.1.
      Section
      2.1 of the Rights Agreement is hereby amended in its entirety, to read:

     

    “The
      Corporation hereby appoints the Rights Agent to act as agent for the Corporation
      in accordance with the terms and conditions hereof, and the Rights 

     

    
      
         

      

      
        1

        
          

        

      

      
         

      

    

     

    Agent
      hereby accepts such appointment. The Corporation may from time to time appoint
      such co-Rights Agents as it may deem necessary or desirable, upon ten (10)
      days’
prior written notice to the Rights Agent. The Rights Agent shall have no duty
      to
      supervise, and in no event shall be liable for, the acts or omissions of any
      such co-Rights Agent.” 

     

    1.4  Section
      21.
      Section
      21 of the Rights Agreement is hereby amended in its entirety, to read:

     

    “The
      Rights Agent or any successor Rights Agent may resign and be discharged from
      its
      duties under this Agreement upon thirty (30) days' notice in writing mailed
      to
      the Corporation and to each transfer agent of the Common Stock or Preferred
      Stock by registered or certified mail, and, at the expense of the Corporation,
      to the holders of the Right Certificates by first-class mail. In the event
      the
      transfer agency relationship in effect between the Company and the Rights Agent
      terminates, the Rights Agent will be deemed to resign automatically on the
      effective date of such termination; and any required notice will be sent by
      the
      Company. The Corporation may remove the Rights Agent or any successor Rights
      Agent upon sixty (60) days' notice in writing, mailed to the Rights Agent or
      successor Rights Agent, as the case may be, and to each transfer agent of the
      Common Stock or Preferred Stock by registered or certified mail, and to holders
      of the Right Certificates by first-class mail. If the Rights Agent shall resign
      or be removed or shall otherwise become incapable of acting, the Corporation
      shall appoint a successor to the Rights Agent. If the Corporation shall fail
      to
      make such appointment within a period of sixty (60) days after giving notice
      of
      such removal or after it has been notified in writing of such resignation or
      incapacity by the resigning or incapacitated Rights Agent or by the holder
      of a
      Right Certificate (who shall, with such notice, submit his Right Certificate
      for
      inspection by the Corporation), then the registered holder of any Right
      Certificate may apply to any court of competent jurisdiction for the appointment
      of a new Rights Agent. Any successor Rights Agent, whether appointed by the
      Corporation or by such a court, shall be (i) a Person organized and doing
      business under the laws of the United States or of any of the States of New
      York, New Jersey, Colorado or California (or of any other state of the United
      States so long as such Person is authorized to do business in any of the States
      of New York, New Jersey, Colorado or California), in good standing, having
      an
      office in any of such States, which is subject to supervision or examination
      by
      federal or state authority and which (or the parent corporation of which) has
      at
      the time of its appointment as Rights Agent a combined capital and surplus
      of at
      least $50,000,000 or (ii) an affiliate of such Person. After appointment, the
      successor Rights Agent shall be vested with the same powers, rights, duties
      and
      responsibilities as if it had been originally named as Rights Agent without
      further act or deed; but the predecessor Rights Agent shall deliver and transfer
      to the successor Rights Agent any property at the time held by it hereunder,
      and
      execute and deliver any further assurance, conveyance, act or deed necessary
      for
      the purpose. In case at the time such successor Rights Agent shall succeed
      to
      the agency created by this Agreement, any of the Right Certificates shall have
      been countersigned but not delivered, any 

    
      
         

      

      
        2

        
          

        

      

      
         

      

    

    such
      successor Rights Agent may adopt the countersignature of a predecessor Rights
      Agent and deliver such Right Certificates so countersigned; and in case at
      that
      time any of the Right Certificates shall not have been countersigned, any
      successor Rights Agent may countersign such Right Certificates either in the
      name of the predecessor or in the name of the successor Rights Agent; and in
      all
      such cases such Right Certificates shall have the full force provided in the
      Right Certificates and in this Agreement. Not later than the effective date
      of
      any such appointment, the Corporation shall file notice thereof in writing
      with
      the predecessor Rights Agent and each transfer agent of the Common Stock or
      Preferred Stock, and mail a notice thereof in writing to the registered holders
      of the Right Certificates. Failure to give any notice provided for in this
      Section 21, however, or any defect therein, shall not affect the legality or
      validity of the resignation or removal of the Rights Agent or the appointment
      of
      the successor Rights Agent, as the case may be.

     

    1.5  Section
      25.1.1.
      Section
      25.1.1 of the Rights Agreement is hereby amended to provide that notices or
      demands authorized by the Rights Agreement made to or on the Corporation shall
      be addressed to: 

     

    “Cytori
      Therapeutics, Inc.

    3020
      Callan Road

    San
      Diego, CA 92121

    Attention:
      Corporate Secretary”. 

     

    1.6  Section
      25.1.2.
      Section
      25.1.2 of the Rights Agreement is hereby amended to provide that notices or
      demands authorized by the Rights Agreement made to or on the Rights Agent shall
      be addressed to: 

     

    “Computershare
      Trust Company, N.A.

    655
      Montgomery Street

    San
      Francisco, CA 94111”. 

     

    1.7  Section
      25.10.
      A new
      Section 25.10 of the Rights Agreement is hereby added as follows: 

     

    “25.10.
      Force
      Majeure.
      

     

    Notwithstanding
      anything to the contrary contained herein, Rights Agent shall not be liable
      for
      any delays or failures in performance resulting from acts beyond its reasonable
      control including, without limitation, acts of God, terrorist acts, shortage
      of
      supply, breakdowns or malfunctions, interruptions or malfunction of computer
      facilities, or loss of data due to power failures or mechanical difficulties
      with information storage or retrieval systems, labor difficulties, war, or
      civil
      unrest.”

     

    1.8  Section
      28.
      A new
      Section 28 of the Rights Agreement is hereby added as follows: 

     

    
      
         

      

      
        3

        
          

        

      

      
         

      

    

     

    “28.
      Beneficial
      Ownership by Olympus Corporation.
      

     

    Notwithstanding
      anything to the contrary in this Agreement: (A) the Beneficial Ownership by
      Olympus Corporation, either individually or together with its Affiliates and
      Associates (collectively, “Olympus”)
      of 20%
      or less of the outstanding shares Common Stock shall not constitute Olympus
      an
      Acquiring Person; and (B) Olympus shall
      not
      be deemed an Acquiring Person either (i) as a result of the acquisition of
      Common Stock by the Corporation which, by reducing the number of shares of
      Common Stock outstanding, increases the proportional number of shares
      Beneficially Owned by Olympus; provided however
      that if
      (1) Olympus would become an Acquiring Person (but for the operation of this
      subclause (B)(i)) as a result of the acquisition of shares of Common Stock
      by
      the Corporation, and (2) after such share acquisition by the Corporation,
      Olympus becomes the Beneficial Owner of any additional shares of Common Stock,
      then Olympus shall be deemed an Acquiring Person, or (ii) if (1) within eight
      (8) days after Olympus would otherwise have become an Acquiring Person (but
      for
      the operation of this subclause (B)(ii)), Olympus notifies the Board of
      Directors of the Corporation that Olympus did so inadvertently and (2) within
      two (2) Business Days (as defined in Section 1.8 hereof) after such
      notification, Olympus is the Beneficial Owner of 20% or less of the outstanding
      shares of Common Stock.”

     

    2.  No
      Other Amendment.
      Except
      as modified by this Amendment, the Rights Agreement, as previously amended
      by
      Amendment No. 1, shall remain in full force and effect without any modification.
      By executing this Amendment below, the Corporation certifies that this Amendment
      has been executed and delivered in compliance with the terms of
      Section 25.2 of the Rights Agreement. This
      Amendment shall be deemed an amendment to the Rights Agreement and shall become
      effective when executed and delivered by the Corporation and the Rights Agent
      as
      provided under Section 25.2 of the Rights Agreement. 

     

    3.  Effect
      of Amendment.
      Except
      as and to the extent expressly modified by this Amendment, the Rights Agreement,
      as previously amended by Amendment No. 1, and the exhibits thereto, shall remain
      in full force and effect in all respects. In the event of a conflict or
      inconsistency between this Amendment and the Rights Agreement, as previously
      amended by Amendment No. 1, and the exhibits thereto, the provisions of this
      Amendment shall govern.

     

    4.  Counterparts.
      This
      Amendment may be executed in several counterparts, each of which shall
      constitute an original and all of which, when taken together, shall constitute
      one agreement.

     

    

    [THIS
      SPACE INTENTIONALLY LEFT BLANK]

     

    
      
        
            

        

         

      

      
        4

        
          

        

      

      
         

        
        

      

    

    The
      parties hereto have caused this Amendment to be executed and delivered as of
      the
      day and year first written above.

     

            Cytori
      Therapeutics,
      Inc.

     

            By:/s/
      Mark E. Saad 

     

            Mark
      E. Saad

            Chief
      Financial
      Officer

    

     

            Computershare
      Trust
      Company, N.A.

            (as
      successor to
      Computershare Trust Company, Inc.)

     

            By:/s/
      Dennis V. Moccia 

     

            Dennis
      V.
      Moccia

            Manager,
      Contract
      Administration

     

     

    
      
         

      

      
        5Exhibit 10.1(a)

THIRD AMENDMENT TO INDUSTRIAL
COMPLEX LEASE

THIS  THIRD AMENDMENT  TO INDUSTRIAL COMPLEX
LEASE (this “Amendment”) is
made and entered into as of January 16, 2007, by and between BRCP
CARIBBEAN PORTFOLIO, LLC, a Delaware limited liability company (“Landlord”), and
ACCURAY INCORPORATED, a California corporation
(“Tenant”).

RECITALS

A.                                   Landlord (as successor in interest to MP
Caribbean, Inc., a Delaware corporation) and Tenant are parties to that certain
Industrial Complex Lease, dated July 9, 2003 (the “Original
Lease”), which Original Lease has been previously amended by that
certain First Amendment to Industrial Complex Lease, dated December 9, 2004,
and that certain Second Amendment to Industrial Complex Lease (the “Second Amendment”), dated September 25, 2006 (collectively,
the “Lease”).  Pursuant to the Lease, Landlord has leased to
Tenant space currently containing approximately 125,568
rentable square feet (the “Premises”)
described as approximately 40,000 rentable square feet of space in that certain
building located at 1310 Chesapeake Terrace, Sunnyvale, California, approximately
32,576 rentable square feet of space in that certain building located at 1314
Chesapeake Terrace, Sunnyvale, California and approximately 52,992 rentable
square feet of space in that certain building located at 1315 Chesapeake
Terrace, Sunnyvale, California (each of the foregoing a “Building”
and together, collectively, the “Buildings”),
which are a part of the approximately 253,540 rentable square foot industrial complex
commonly known as Caribbean Corporate Center (the “Industrial
Complex”).

B.                                     Tenant and Landlord mutually desire that the
Lease be amended on and subject to the following terms and conditions.

NOW, THEREFORE, in consideration of the mutual covenants and
agreements herein contained and other good and valuable consideration, the
receipt and sufficiency of which are hereby acknowledged, Landlord and Tenant
agree as follows:

1.                                       Amendment.  Effective as of the date hereof
(unless different effective date(s) is/are specifically referenced in this
Section), Landlord and Tenant agree that the Lease shall be amended in
accordance with the following terms and conditions:

1.1                                Expansion Space Improvements.

1.1.1                        Tenant hereby acknowledges
and agrees that on December 19, 2006, Landlord delivered to Tenant at that
portion of the Premises located in the Building at 1315 Chesapeake Terrace,
Sunnyvale, California  (the “Carpet Delivery Date”) the new carpeting described in
Section 1 of Exhibit B to the Second Amendment (the “Carpeting”).  Notwithstanding anything in the Second
Amendment to the contrary, Landlord shall have no obligation to install the
Carpeting at the Premises nor to provide any allowance or other incentive in
connection with the same, except as expressly provided below.  On or before June 1, 2007, Tenant shall
install the Carpeting at the Premises in accordance with the terms and
conditions hereof and otherwise in accordance with the terms of the Lease.  Landlord
shall have the right to approve the contractor to be retained by Tenant to
install the Carpeting in the Premises. 
Tenant shall be responsible for all elements of the

 1
 

installation
of the Carpeting at the Premises. 
Landlord’s approval of the contractors to install the Carpeting shall
not be unreasonably withheld.

Provided
Tenant is not in default under the Lease, as amended hereby, beyond any
applicable notice and cure periods, Landlord
agrees to contribute up to $37,992.00 (“Landlord’s Contribution”) toward the
cost of installing the Carpeting in the Premises.  Landlord’s Contribution shall be paid to
Tenant within thirty (30) days following receipt by Landlord of
(a) receipted bills covering all labor expended in connection with the
installation of the Carpeting in the Premises; (b) a sworn contractor’s
affidavit from the contractor and a request to disburse from Tenant containing
an approval by Tenant of the work done; (c) full and final waivers of
lien; and (d) the certification of Tenant and its contractor that the
Carpeting has been installed in a good and workmanlike manner and in accordance
with applicable laws, codes and ordinances. 
Landlord’s Contribution shall be disbursed in the amount reflected on
the receipted bills meeting the requirements above.  Notwithstanding anything herein to the
contrary, Landlord shall not be obligated to disburse any portion of Landlord’s
Contribution during the continuance of an uncured default under the Lease, as
amended hereby, and Landlord’s obligation to disburse shall only resume when
and if such default is cured.

Tenant is solely responsible for the condition and repair
of the Carpeting and any damage caused to the Carpeting.  None of the Indemnities (as defined in
Article 21 of the Original Lease) shall be liable and Tenant hereby waives all
claims against them for any damage to the Carpeting (except to the extent the
same is caused by the gross negligence or willful misconduct of Landlord) and/or
injury caused by the presence of such Carpeting in the Premises.  Tenant shall protect, indemnify and hold the
Indemnitees harmless from and against any and all loss, claims, liability or
costs (including court costs and attorney’s fees) incurred by reason of any
damage to the Carpeting (excluding any damage caused by the gross negligence or
willful misconduct of Landlord) and/or any injury caused by the presence of the
Carpeting in the Premises.  The foregoing
provisions of this Section 1.1 shall survive the termination of the Lease, as
amended hereby, with respect to any claims or liability accruing prior to such
termination.

1.1.2                       Notwithstanding anything herein or in the Second Amendment to the
contrary, Tenant hereby acknowledges and agrees that (a) except with
respect to the performance of any restoration or repairs on the base Building
systems in the Expansion Space required of Landlord pursuant to Section 9 of
the Second Amendment (as referenced in Paragraph 3 of Exhibit B to the Second
Amendment) (the foregoing exception referred to herein as the “Exception”), as of the Carpet Delivery Date, Landlord has fully
satisfied Landlord’s obligations with respect to the completion of the
Expansion Space Improvements set forth in Exhibit B to the Second Amendment and
Tenant hereby waives any claims against the Indemnitees with respect to any
Expansion Space Improvements described in Exhibit B to the Second Amendment
that were not complete as of the Carpet Delivery Date, and (b) Tenant
hereby accepts the Expansion Space in its as-is condition as of the Carpet
Delivery Date, except with respect to the Exception.

 2
 

1.1.3                       Landlord and Tenant acknowledge and agree that, notwithstanding
anything set forth herein to the contrary, the following obligation of Landlord
pursuant to Paragraph 1 of Exhibit B to the Second Amendment shall
remain in full force and effect: Landlord’s obligation to obtain from the
appropriate governmental authorities all approvals necessary for the occupancy
of the Premises with respect to the Expansion Space Improvements actually
performed by Landlord or its contractors in the Expansion Space (the fifth
sentence of Paragraph 1 of Exhibit B to the Second Amendment).

1.2                                 Expansion Effective Date. 
Landlord and Tenant hereby acknowledge and confirm that the Expansion
Effective Date occurred on November 15, 2006, and that as of the Expansion
Effective Date, Tenant’s obligation to pay the minimum guaranteed rental with
respect to the Expansion Space set forth in the Second Amendment commenced.

2.                                       Miscellaneous.

2.1                                This
Amendment sets forth the entire agreement between the parties with respect to
the matters set forth herein.  There have
been no additional oral or written representations or agreements.  Under no circumstances shall Tenant be
entitled to any rent abatement, improvement allowance, leasehold improvements,
or other work to the Premises, or any similar economic incentives that may have
been provided Tenant in connection with entering into the Lease, unless
specifically set forth in this Amendment or the Second Amendment.

2.2                                Except
as herein modified or amended, the provisions, conditions and terms of the
Lease shall remain unchanged and in full force and effect.

2.3                                In
the case of any inconsistency between the provisions of the Lease and this
Amendment, the provisions of this Amendment shall govern and control.

2.4                                Submission
of this Amendment by Landlord is not an offer to enter into this Amendment but
rather is a solicitation for such an offer by Tenant.  Landlord shall not be bound by this Amendment
until Landlord has executed and delivered the same to Tenant.

2.5                                The
capitalized terms used in this Amendment shall have the same definitions as set
forth in the Lease to the extent that such capitalized terms are defined
therein and not redefined in this Amendment.

2.6                                Tenant
hereby represents to Landlord that Tenant has dealt with no broker in connection
with this Amendment.  Tenant agrees to
indemnify and hold Landlord, its members, principals, beneficiaries, partners,
officers, managers, investors, directors, employees, mortgagee(s) and agents,
and the respective principals and members of any such agents harmless from all
claims of any brokers claiming to have represented Tenant in connection with
this Amendment.  Landlord hereby
represents to Tenant that Landlord has dealt with no broker in connection with
this Amendment.  Landlord agrees to
indemnify and hold Tenant, its members, principals, beneficiaries, partners,
officers, directors, employees, and agents, and the respective principals and
members of any such agents harmless from all claims of any brokers claiming to
have represented Landlord in connection with this Amendment.

 3
 

2.7                                Each
signatory of this Amendment represents hereby that he or she has the authority
to execute and deliver the same on behalf of the party hereto for which such
signatory is acting.  Tenant hereby
represents and warrants that neither Tenant, nor any persons or entities
holding any legal or beneficial interest whatsoever in Tenant, are (i) the
target of any sanctions program that is established by Executive Order of the
President or published by the Office of Foreign Assets Control, U.S. Department
of the Treasury (“OFAC”); (ii)
designated by the President or OFAC pursuant to the Trading with the Enemy Act,
50 U.S.C. App.  § 5, the International
Emergency Economic Powers Act, 50 U.S.C. §§ 1701-06, the Patriot Act, Public Law
107-56, Executive Order 13224 (September 23, 2001) or any Executive Order of
the President issued pursuant to such statutes; or (iii) named on the following
list that is published by OFAC: “List of Specially Designated Nationals and
Blocked Persons.” If the foregoing representation is untrue at any time during
the Term, an uncured event of default under the Lease will be deemed to have
occurred, without the necessity of notice to Tenant.

2.8                                Redress
for any claim against Landlord under the Lease and this Amendment shall be
limited to and enforceable only against and to the extent of Landlord’s
interest in the Building.  The
obligations of Landlord under the Lease are not intended to and shall not be
personally binding on, nor shall any resort be had to the private properties
of, any of its trustees or board of directors and officers, as the case may be,
its investment manager, the general partners thereof, or any beneficiaries,
stockholders, employees, or agents of Landlord or the investment manager.

IN WITNESS
WHEREOF, Landlord and
Tenant have entered into and executed this Amendment as of the date first
written above.

 4
 

 

	
  

  	
  LANDLORD:

  
	
   

  	
   

  
	
   

  	
  BRCP CARIBBEAN PORTFOLIO, LLC, 

  a Delaware limited liability company

  
	
   

  	
   

  
	
   

  	
   

  
	
   

  	
  By:

  	
   

  	
  /s/ Craig Vought

  	
   

  	
   

  
	
   

  	
   

  
	
   

  	
  Name:

  	
   

  	
  Craig Vought

  	
   

  	
   

  	
   

  
	
   

  	
   

  
	
   

  	
  Title:

  	
   

  	
  Managing Partner

  	
   

  	
   

  
	
   

  	
   

  
	
   

  	
   

  
	
   

  	
  TENANT:

  
	
   

  	
   

  
	
   

  	
  ACCURAY INCORPORATED, 

  a California corporation

  
	
   

  	
   

  
	
   

  	
  By:

  	
   

  	
  /s/ Chris A.
  Raanes

  	
   

  	
   

  
	
   

  	
   

  
	
   

  	
  Name:

  	
   

  	
  Chris A. Raanes

  	
   

  	
   

  	
   

  
	
   

  	
   

  
	
   

  	
  Title:

  	
   

  	
  COO

  	
   

  	
   

  
										

 

 

	
  

  	
  By:

  	
  /s/ Darren J.
  Milliken

  	
   

  	
   

  
	
   

  	
  Name:

  	
  Darren J.
  Milliken

  	
   

  
	
   

  	
   

  
	
   

  	
  Title:

  	
  General Counsel

  	
   

  
							

 

 5

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