Document:

Exhibit 4.6

 

SIEMENS ID

 

Agreement

 

by and between

 

Profound
Medical Inc.

 

(-
hereinafter referred to as “the Receiver” -)

 

and

 

SIEMENS Healthcare GmbH

 

(-
hereinafter referred to as “SIEMENS” -)

 

- the
Receiver and SIEMENS hereinafter referred to individually 

as “PARTY” or collectively as “PARTIES”
-

 

on the provision of information regarding
SIEMENS’ interface

 

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Contents

 

	Preamble 	3
	Article 1 - Definitions 	3
	Article 2 - License 	5
	Article 3 - Obligations of the PARTIES 	5
	Article 4 - INTERFACE 	7
	Article 5 - Provision of DEVELOPER SERVICES, INFORMATION and the SDK 	9
	Article 6 - Pricing 	12
	Article 7 - Limitations: Permits, Regulatory Approvals and Standards 	13
	Article 8 - Billing 	16
	Article 9 - Marketing 	17
	Article 10 - Monitoring of Usage Data 	17
	Article 11 - Revocation of the AUTHORIZATION KEY and LICENSE KEY 	17
	Article 12 - Notification Page 	18
	Article 13 - Support 	18
	Article 14 - Liability 	19
	Article 15 - Confidentiality 	20
	Article 16 - Agreement Term, Notification and CHANGE-OF-CONTROL 	21
	Article 17 - Force Majeure 	22
	Article 18 - Miscellaneous 	23
	Article 19 - Arbitration and Substantive Law 	24

 

Annex 1 – Specification of
INFORMATION

Annex 2 – Specification of
PRODUCTS

Annex 3 – Agreement for risks
exported in using Access-i

 

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Preamble

 

The
PARTIES entered in a co-marketing and co-selling
agreement on February 26, 2016 (the “Original Agreement”).

 

The
PARTIES now wish to substitute and replace the Original Agreement with this Agreement in connection with all sales and other activities
as of the Effective Date, such that all prior financial commitments
and obligations are released and replaced with the financial commitments and obligations of this Agreement.

 

SIEMENS
is prepared to supply certain interface information and/or other documentation to the Receiver to enable the Receiver to use the
Access-I interface for interfacing PRODUCTS to certain SIEMENS
MAGNETOM Scanners pursuant to the terms of this Agreement.

 

The PARTIES therefore agree as follows:

 

Article
1 - Definitions

 

		1.1	INFORMATION hereinafter refers to know-how,
information and/or documentation supplied by SIEMENS to the Receiver as
detailed in Annex 1.

 

		1.2	PRODUCTS hereinafter refer to Receiver’s products developed for the ablation of soft tissue
in conjunction with MRI scanners.

 

		1.3	SIEMENS MAGNETOM SCANNERS hereinafter
refer to certain SIEMENS MAGNETOM Scanners which the Receiver intends to interface to its PRODUCTS using the INFORMATION and
which are equipped with the INTERFACE.

 

		1.4	CHANGE OF CONTROL hereinafter means, with
respect to the Receiver, one of the following events or series
of related events: a) a sale of all or substantially all of the Receiver’s assets, voting stock or securities or business
relating to this Agreement; b) a merger, reorganization or consolidation
involving the Receiver in which the stockholders of the Receiver immediately prior to such transaction cease to own collectively
a majority of the voting equity securities of the successor entity; or c) a person or group of persons acting in concert acquire
fifty percent (50%) or more of the voting equity securities of
the Receiver.

 

		1.5	AFFILIATE shall mean, with
respect to a PARTY, a subsidiary, meaning
a company in which such PARTY owns or controls, directly or indirectly, more
than fifty percent (50%) of the stock or voting rights,
or a parent company, meaning
a company which owns or controls, directly or indirectly,
more than fifty percent (50%)
of the stock or voting rights of the relevant PARTY, or a company
which is a subsidiary of such PARTY’s parent company.

 

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		1.6	COMPETITOR hereinafter refers to any entity
which has a product line that competes with SIEMENS MAGNETOM SCANNERS.

 

		1.7	END USER hereinafter refers to an individual,
company, institution
or other legal entity other than the PARTIES or an AFFILIATE of SIEMENS that uses or intends to use the PRODUCTS in combination
with a SIEMENS MAGNETOM SCANNER to treat patients or to conduct any form of research.

 

		1.8	OTHERS hereinafter refers to any individual,
company, institution
or other legal entity other than the PARTIES or any AFFILIATE of either of the PARTIES or END USERS.

 

		1.9	IP hereinafter refers to intellectual
property, which is patents, rights
to inventions, copyright and related rights, trademarks, trade names and domain names, rights to sue for passing off, rights in
designs, rights in computer software, database rights, rights in
confidential information (including know-how and trade secrets)
and any other equivalent intellectual property rights, in each
case whether registered or unregistered and including all applications (or rights to apply) for, and renewals or extensions
of, such rights or and all similar or equivalent rights or forms
of protection which subsist now or in the future, in any part of
the world.

 

		1.10	INTERFACE hereinafter refers to the Access-i
(Scanner Remote Control) Interface for 3rd party device integration developed and provided through SIEMENS.

 

		1.11	DEVELOPER SERVICES hereinafter refers
to the activities conducted by SIEMENS to support the development efforts of the Receiver to achieve compatibility of the Receiver’s
PRODUCTS with the INTERFACE; this does not include any other development efforts in the Receiver’s PRODUCTS.

 

		1.12	SOFTWARE DEVELOPER KIT (SDK) hereinafter
refers to a software tool developed and provided through SIEMENS to support the development efforts of the Receiver to achieve
compatibility of the Receiver’s PRODUCTS with the INTERFACE.

 

		1.13	AUTHORIZATION KEY hereinafter refers to
an authorization key file installed on the Receiver’s PRODUCTS enabling the use of the PRODUCTS in connection with the INTERFACE
by End Users. The AUTHORIZATION KEY is time limited and unique to each individual MAGNETOM SCANNER.

 

		1.14	LICENSE KEY hereinafter refers to a software
license and license key file installed on the SIEMENS MAGNETOM SCANNERS enabling the INTERFACE on SIEMENS MAGNETOM SCANNERS.
The LICENSE KEY has to be purchased by the END USER (at no additional
cost to Receiver) from Siemens as a one-time purchase. The
provision and the cost of this LICENSE KEY are not covered by this agreement.

 

		1.15	EFFECTIVE DATE hereinafter means January
21st, 2019.

 

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Article
2 - License

 

		2.1	Subject to the terms and conditions set
out in this Agreement, SIEMENS shall make available and provide
to the Receiver (and its personnel and subcontractors) the INFORMATION, DEVELOPER
SERVICES, the SDK and the AUTHORIZATION KEY and herewith grants
to the Receiver under this Agreement the following rights:

 

		2.2	A non-exclusive,
non-transferable, worldwide
right and license to use the INFORMATION, DEVELOPER SERVICES,
the SDK and the AUTHORIZATION KEY for the sole purpose of interfacing
PRODUCTS to certain SIEMENS MAGNETOM SCANNERS and to make available and deliver such adapted PRODUCTS for use by END USERS for
use in connection with SIEMENS MAGNETOM SCANNERS for research and/or development purposes and/or for medical treatment.
The license granted herein includes the right to grant sublicenses to
Receiver’s AFFILIATES and service providers to Profound carrying out Profounds business and shall exclusively apply to the
Receiver’s PRODUCTS and any successor product to the Receiver’s PRODUCTS which replaces the PRODUCT in question,
but not cover any other product of the Receiver. Receiver will not reverse
engineer the SDK, the INTERFACE or the AUTHORIZATION KEY for the
purpose of the development of adaptations of the Receiver’s PRODUCTS to any other customer other than SIEMENS customers.

 

Notwithstanding
the above, nothing in this Agreement shall limit the Receiver from
developing PRODUCTS that can interface with scanners from multiple suppliers (i.e. that can interface with both SIEMENS MAGNETOM
SCANNERS and scanners from other manufacturers) as long as Receiver does not use or disclose to such other manufacturers any CONFIDENTIAL
INFORMATION provided to the Receiver under this Agreement in the development of interfaces for such other manufacturers’
scanners.

 

Article
3 - Obligations of the PARTIES

 

		3.1	Obligations
of SIEMENS:

 

		3.1.1	SIEMENS will provide the Receiver with
information on the related product risks as referred to in Annex 3 and inform the Receiver of any updates during the lifetime of
the INTERFACE.

 

		3.1.2	SIEMENS will provide the Receiver with
AUTHORIZATION KEYS on a perpetual basis for each individual SIEMENS MAGNETOM SCANNER enabling the use of the INTERFACE according
to the INTERFACE description.

 

		3.1.3	SIEMENS will provide the END USER with
the LICENSE KEY to enable use of the SDK with the INTERFACE.

 

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		3.1.4	SIEMENS will use commercially reasonable
efforts to notify the Receiver of any actual or planned change regarding the INTERFACE that might compromise the compatible use
of the Receivers PRODUCTS with the SIEMENS INTERFACE, and to provide
the Receiver with such INFORMATION and/or collaborative testing as may be reasonably required in order for the Receiver to sufficiently
maintain or update the Receiver’s PRODUCTS and, if applicable,
the Technical Documentation and/or clinical dossier of such PRODUCTS in
accordance with Directive 93/42/EEC or Regulation (EU) 2017/745 on medical devices, as applicable, to
ensure continued compatible use with the INTERFACE in view of such change no less than 120 days
in advance of the time at which the change becomes effective for End Users SIEMENS MAGNETOM SCANNERs. More generally Siemens
will aid reasonable requests to support the attainment of data for validation runs, compatibility
testing and other such assistance; however the determination of reasonable will be at Siemens discreation.

 

		3.1.5	SIEMENS will use commercially reasonable
efforts to provide the DEVELOPER SERVICES and the SDK to the Receiver.

 

		3.1.6	SIEMENS shall not have any other obligations
than those expressly described in this Agreement. For the sake
of clarity, SIEMENS shall not be obligated to disclose any further
information than the INFORMATION described in Annex 1.

 

		3.2	Obligations
of the Receiver:

 

		3.2.1	The Receiver acknowledges and agrees that
the AUTHORIZATION KEY enables the use of the INTERFACE according to the INTERFACE description and that its improper use could cause
damage to the system and patient injury. It is the responsibility
of the Receiver to comply with all applicable legal requirements related to the PRODUCTS, to understand all consequences of using
the PRODUCTS or the INTERFACE on the basis of the INFORMATION provided by SIEMENS in Annex 1 and the product risk information provided
in Annex 3, and to refrain from such use if there is any reasonable
question of legality, hardware or other property damage, or patient
injury.

 

		3.2.2	If
the use of the INTERFACE is for the purpose of research conducted or sponsored by the Receiver involving human subjects,
it requires appropriate documentation, review
and approval by an appropriate Ethics Committee or by the Receiver’s Institutional Review Board (“IRB”) according
to applicable medical device law and compliance with all Ethics Committee/IRB recommendations and requirements. No human subject
research may be commenced by Receiver or a party sponsored by Receiver before Ethics Committee/IRB approval has been granted.

 

		3.2.3	The Receiver accepts the exported product
risks described in Annex 3 to this contract and any risks as updated by SIEMENS according to Article 3.1.1.
It is the responsibility of the Receiver to assess the measures defined
in Annex 3 within their processes and to ensure that reasonable measures are in place to mitigate these risks in using the
INTERFACE’s functionality.

 

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		3.2.4	For the issuance of an AUTHORIZATION KEY,
the Receiver has to provide to SIEMENS the serial number of the SIEMENS
MAGNETOM SCANNER the PRODUCT will be interfaced with and the duration the PRODUCT is intended to be compatible with the SIEMENS
MAGNETOM SCANNER, whereas AUTHORIZATION KEYS can be deactivated
on request

 

		3.2.5	The AUTHORIZATION KEY mentioned in Article
3.1.2 (and any other information provided by SIEMENS) shall be
(i) used by the Receiver exclusively to use the INTERFACE for interfacing PRODUCTS to certain SIEMENS MAGNETOM SCANNERS,
unless otherwise expressly agreed to in writing by SIEMENS and (ii)
kept strictly confidential and encrypted or in some secure fashion by the Receiver with the same degree of care as is used with
respect to the Receiver’s own equally important confidential information to avoid disclosure to any third party, but
at least with reasonable care. Without limiting use of the PRODUCTS
by END USERS the AUTHORIZATION KEY shall not be made available to OTHERs and shall be made available to AFFILIATES, Receiver’s
personnel, contractors for the sole purpose of interfacing and
using the PRODUCTS with the dedicated SIEMENS MAGNETOM SCANNER according to the terms and conditions of this Agreement.

 

		3.2.6	The Receiver has the sole responsibility
for the combined products and it is the Receiver’s responsibility to ensure that all legal and country specific requirements
for such a combination are adhered to, following the obligations
of the country in which the combination is used. This includes,
for example, that no unacceptable risks can be caused by the combination to patients or users. SIEMENS takes no responsibility
regarding the combination of the products even though SIEMENS supports the connectivity to the INTERFACE; provided that any damage
occurred, if any, was
not caused by a gross negligent act or omission of SIEMENS.

 

Article
4 - INTERFACE

 

		4.1	Update Cycles

 

SIEMENS
is prepared to continuously develop new functionalities and features for the INTERFACE at no additional cost to Receiver. Such
new features and functionalities are intended to be released in up to two application updates per year in accordance with Section
3.1.4.
Security related updates and patches can be introduced whenever deemed necessary by SIEMENS. SIEMENS
will use commercially reasonable efforts to maintain the compatibility
of the PRODUCT with the SIEMENS MAGNETOM SCANNER and provide all necessary information and assistance to Receiver as outlined
in Section 3.1.4.

 

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		4.2	Changes to Requirements

 

SIEMENS
may change and/or issue additional technical requirements for the combination of the PRODUCT with the SIEMENS MAGNETOM SCANNER
using the INTERFACE at any time by using commercially reasonable efforts to notifying the Receiver at SIEMENS’ earliest
convenience, but no less than 120 days
before the changed technical requirements become effective, provided that SIEMENS will endeavor to maintain compatibility of the
INTERFACE with any of the Receiver’s PRODUCTS compliant with the requirements at the time of their submission during next
two (2) update cycles of the INTERFACE following the submission of the respective PRODUCT at minimum. Notwithstanding
the foregoing, the Receiver has to ensure that the combination
of its PRODUCTS to the SIEMENS MAGNETOM SCANNER is still working with the changes in the requirement and SIEMENS shall provide
all necessary information and assistance in this respect, as outlined
in Section 3.1.4. Such notice period may be shortened by SIEMENS,
and the requirements regarding maintenance of compatibility will not apply
only to the extent that, based on SIEMENS’ reasonable judgment,
SIEMENS believes that a shorter notice period or incompatibility is
necessary in order to avoid any: (i) threat to the security or functionality of the INTERFACE or the DEVELOPER SERVICES; (ii) adverse
impact on the Receiver, SIEMENS, the
Receiver’s or SIEMENS’ AFFILIATES, END USERS,
or any third party, including,
without limitation, any risk of personal injury; and/or (iii) subject the Receiver, SIEMENS, the
Receiver’s or SIEMENS’ AFFILIATES, END USERS,
or any third party to material liability for personal injury or IP infringement;
in each case, so long as SIEMENS takes commercially reasonable efforts to maintain the compatibility of the PRODUCT with the SIEMENS
MAGNETOM SCANNER. To the extent the Receiver is, due
to such changes, materially deprived of the benefits of the INTERFACE or the SDK, the Receiver is entitled to terminate the Agreement
in writing with effect upon effectiveness of the change at the earliest and the Receiver will be entitled to a refund of all amounts
paid with regards to the affected AUTHORIZATION KEYs by Receiver to SIEMENS over the period of incompatability.

 

		4.3	Changes to the INTERFACE

 

SIEMENS
updates and further develops the technology, features and functionalities of the INTERFACE and is under no obligation to maintain
prior versions thereof. Upon the provision of a modified or new version of the INTERFACE, the Receiver is no longer entitled to
use previous versions. Should material changes to the INTERFACE be implemented which have an impact on the Receiver’s use,
whereas these impacts are known to SIEMENS, or should agreed functionalities be restricted or disabled, SIEMENS will use commercially
reasonable efforts to notify the Receiver at SIEMENS’ earliest convenience, but no less than 120 days before the changes
become effective. Such notice period may be shortened by SIEMENS only to the extent that, based on SIEMENS’ reasonable judgment,
SIEMENS believes that a shorter notice period is necessary in order to avoid any: (i) threat to the security or functionality
of the INTERFACE; (ii) adverse impact on the Receiver, SIEMENS, the Receiver’s or SIEMENS’ Affiliates, END USERS,
or any third party, including, without limitation, any risk of personal injury; and/or (iii) subject the Receiver, SIEMENS,
the Receiver’s or SIEMENS’ Affiliates, END
USERS, or any third party to material liability for personal injury
or IP infringement; in each case, so long as SIEMENS takes commercially
reasonable efforts to maintain the compatibility of the PRODUCT with the SIEMENS MAGNETOM SCANNER. To
the extent the Receiver is, due to such changes, materially deprived of the benefits of the INTERFACE, the
Receiver is entitled to terminate the Agreement in writing with effect upon effectiveness of the change at the earliest and Receiver
will be entitled to a refund of all amounts with regards to the affected AUTHORIZATION KEYs paid by Receiver to SIEMENS over the
period of incompatability.

 

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		4.4	Freedom from Defects in Title

 

SIEMENS
represents, warrants and covenants that during the term of this Agreement, the
Receiver’s use of the INTERFACE as permitted under the Agreement does not infringe upon a patent, copyright, trade secret,
or other intellectual property right in or to such INTERFACE in the country
where SIEMENS has its seat or in countries where SIEMENS have put SIEMENS MAGNETOM SCANNERS on the market. The
Receiver acknowledges that SIEMENS and/or its AFFILIATES is not responsible for an infringement of any such intellectual property
rights to the extent it is due to: (i) the Receiver’s failure to use the most current version of or a defect correction or
patch supplied by SIEMENS; (ii) the combination, operation,
or use of the INTERFACE in conjunction with any non-SIEMENS information
or with any third-party software, equipment, materials,
or products other than as contemplated by the INFORMATION; or (iii) an adjustment or configuration of the INTERFACE not made by
SIEMENS (or on its behalf). Notwithstanding any deviating and/or
additional obligations expressly set forth in the Agreement, SIEMENS will neither assume any additional obligation nor responsibility
that Receiver’s use of the INTERFACE complies with applicable law.

 

Article
5 - Provision of DEVELOPER SERVICES, INFORMATION
and the SDK

 

		5.1	Service Standards

 

During
the term of the Agreement and subject to Article 5.2 to Article
5.4, SIEMENS
will provide DEVELOPER SERVICES as a service in conformance with the features and functionalities as described in the Agreement
and the INFORMATION. SIEMENS will provide the Receiver with information
and make the SDK available in a manner suitable for adapting the Receiver’s PRODUCTS to the INTERFACE. This
service will include providing:

 

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		·	Technical descriptions

		·	SDK including

		o	INTERFACE Simulator

		o	Test Client for the INTERFACE

		·	Library of examples to demonstrate programming
and/ or usage of certain functionalities

		·	Introductory webinar support/ conference
call (up to one hour)

		·	Email support to answer basic questions

		·	Up to two follow-up
conference calls to discuss questions (up to one hour each)

		·	One introduction call for each regular
update (up to one hour)

 

The
service does not include code check or any development work, neither
software nor hardware related.

 

		5.2	Limitations

 

Except as set forth in the
Agreement:

 

(a)
SIEMENS assumes no obligations to the Receiver in connection with, and
any statements about the INTERFACE, the DEVELOPER SERVICES,
the SDK and the INFORMATION. It
does constitute merely technical information and not obligations of SIEMENS.

 

(b) None of the PARTIES’
obligations under the Agreement shall be deemed to constitute a guaranteed quality (zugesicherte Eigenschaft) or other guarantee
(Garantie); and

 

(c)
Each of the PARTIES disclaims any strict liability (verschuldensunabhängige Haftung) for defects and non-conformance already
existing when the Agreement was concluded.

 

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		5.3	Changes to DEVELOPER SERVICES

 

Unless
expressly agreed otherwise, SIEMENS provides the DEVELOPER SERVICES and the SDK as standard services and enables the Receiver
to use the agreed DEVELOPER SERVICES and the SDK made generally available by SIEMENS to its other receivers. SIEMENS will update
and further develop the technology, features and functionalities
of the DEVELOPER SERVICES and the SDK and is under no obligation to maintain prior versions thereof. Upon
the provision of a modified or new version of the DEVELOPER SERVICES and the SDK or any other content, the
Receiver is no longer entitled to use previous versions. Should material changes to the DEVELOPER SERVICES or the SDK be implemented
which have an impact on the Receivers use or should agreed DEVELOPER SERVICES or SDK functionalities be restricted or disabled,
SIEMENS will notify the Receiver at least one hundred eighty (180) days before the changes become effective. Such
notice period may be shortened only to the extent that, based on
SIEMENS reasonable judgment, SIEMENS believes that changes are
necessary in order to avoid any: (i) threat to the security or functionality of the INTERFACE or the DEVELOPER SERVICES or the
SDK; (ii) adverse impact on the Receiver, SIEMENS, the Receiver’s
or SIEMENS’ Affiliates, END USERS, or any third party,
including, without
limitation, any risk of personal injury; and/or (iii) subject the
Receiver, SIEMENS, the Receiver’s or SIEMENS’ Affiliates,
END USERS, or any third party to material liability for personal
injury or IP infringement; in each case, so long as SIEMENS takes
commercially reasonable efforts to maintain the compatibility of the PRODUCT with the SIEMENS MAGNETOM SCANNER. To
the extent the Receiver is, due to such changes, materially deprived
of the benefits of the DEVELOPER SERVICES or SDK, the Receiver
is entitled to terminate the Agreement in writing with effect upon effectiveness of the change at the earliest and Receiver will
be entitled to a refund of all amounts paid by Receiver with regards to the affected AUTHORIZATION KEYs to SIEMENS over the period
of incompatability.

 

		5.4	Discontinuation of Services

 

SIEMENS
may discontinue the provision of DEVELOPER SERVICES or the SDK in relation to a PRODUCT for use by an END USER at any time if the
respective AUTHORIZATION KEY or LICENSE KEY has been revoked by SIEMENS according to Article 11 - Suspension
of the AUTHORIZATION KEY and LICENSE KEY or the Agreement has been terminated according to Article16.2.

 

		5.5	Place of Performance

 

SIEMENS
provides the Receiver access to the DEVELOPER SERVICES and the SDK to be provided over the internet at the WAN exit of the data
center used by SIEMENS. Unless otherwise agreed, SIEMENS
will use a data center in Germany to provide the DEVELOPER SERVICES and the SDK. SIEMENS
reserves the right to change the data center location and use additional data centers at any time and will inform the Receiver
of this in due time, provided that any such data centers will be
within the European Union. SIEMENS will ensure that AUTHORIZATION
KEYS are generated, transferred, and/or revoked from the SIEMENS
Headquarter only.

 

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		5.6	Freedom from Defects in Title

 

SIEMENS
represents, warrants and covenants that during the term of this
Agreement, the Receiver’s use of the DEVELOPER SERVICES and SDK as permitted under the Agreement does not infringe upon a
patent, copyright, trade secret, or
other intellectual property right in or to such DEVELOPER SERVICES and SDK in the country where SIEMENS has its seat or in countries
where SIEMENS have put SIEMENS MAGNETOM SCANNERS on the market. The
Receiver acknowledges that SIEMENS and/or its AFFILIATES is not responsible for an infringement of any such intellectual property
rights to the extent it is due to: (i) the Receiver’s failure to use the most current version of or a defect correction
or patch supplied by SIEMENS for DEVELOPER SERVICES or the SDK; (ii) the combination, operation,
or use of the DEVELOPER SERVICES or the SDK in conjunction with any non-SIEMENS
information or with any third-party software, equipment, materials,
or products other than as contemplated by the INFORMATION; or (iii) an adjustment or configuration of the DEVELOPER SERVICES
or SDK not made by SIEMENS (or on its behalf). Notwithstanding any deviating and/or additional obligations expressly set forth
in the Agreement, SIEMENS will neither assume any additional obligation
nor responsibility that Receiver’s use of the DEVELOPER SERVICES or the SDK comply with applicable law.

 

Article
6 - Pricing

 

		6.1	As consideration that SIEMENS fulfills
the described obligations and provides the described support the PARTIES agree upon a one-time
fixed license fee of $100,000 USD to be paid to SIEMENS.

 

		6.2	SIEMENS shall be entitled to invoice the
Receiver the one-time fixed license fee ten (10)
days after the effective date.

 

		6.3	As consideration for the licenses granted under this Agreement the PARTIES agree upon a yearly
license fee calculated based on the number of SIEMENS MAGNETOM SCANNERS being used for patient treatment:

 

		•	[pricing information redacted]
USD per scanner per year for the first 10 connected SIEMENS MAGNETOM
SCANNERS (Scanner 1 – 10)

 

		•	[pricing information redacted]
USD per scanner per year for additional 20 connected SIEMENS MAGNETOM
SCANNERS (Scanner 11 – 30)

 

		•	[pricing information redacted] USD per scanner per year for additional 70 connected SIEMENS
MAGNETOM SCANNERS (Scanner 31 – 100)

 

		•	[pricing information redacted]
USD per scanner for additional SIEMENS MAGNETOM SCANNERS exceeding 100.

 

The
yearly license fee shall be prorated based on the number of days that elapsed during the year during which the SIEMENS MAGNETOM
SCANNERS are in use during the applicable year. There shall be
no yearly license fees due in respect of SIEMENS MAGNETOM SCANNERS which are already in use as of the Effective Date until the
beginning of the second year of this Agreement.

 

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Any
SIEMENS MAGNETOM SCANNERS which are in any year used solely for the purpose of pre-clinical
or clinical research, whereas the Receiver is not getting any revenue from the END USER, will
not be subject to any license fees. Receiver will advise SIEMENS
of the specific SIEMENS MAGNETOM SCANNERS being used solely for pre-clinical or clinical research and, upon
request, Receiver will provide an annual attestation as to the
number and location of any such SIEMENS MAGNETOM SCANNERS.

 

Article
7 - Limitations: Permits, Regulatory Approvals and Standards

 

		7.1	The
Receiver acknowledges and agrees that:

 

		7.1.1	Operation of SIEMENS MAGNETOM SCANNERS
demands observance of the applicable statutory provisions (e.g.,
in the EU, Directive
93/42/EEC on medical devices (“MDD”) and Regulation (EU) 2017/745 on medical devices (“MDR”), to become
fully applicable on 26 May 2020) or any future revisions / successor
requirements and is limited to particular indicated uses.

 

		7.1.2	Any changes to SIEMENS MAGNETOM SCANNERS
by the Receiver, its AFFILIATES or OTHERS are not covered by CE labeling or regulatory approval or other applicable statutory provisions
and can be relevant for patient safety.

 

		7.1.3	As part of the INFORMATION, SIEMENS
shall only provide the documentation outlined in Annex 1 and does not foresee providing customized documentation, in particular
not any part of the END USER documentation for the PRODUCTS and the combination of the PRODUCTS to the SIEMENS MAGNETOM SCANNER.
Upon Receiver’s request, SIEMENS shall however provide reasonable
assistance and information needed for testing and documenting such combination as related to the INTERFACE only and not for MR
compatability in general. However, more generally Siemens will aid reasonable requests to support the attainment of data for validation
runs, compatibility testing and other such assistance; however the determination of reasonable will be at Siemens discreation.

 

		7.1.4	SIEMENS does not assume any responsibility
for the proper or safe functioning of the Receiver’s PRODUCTS and/or its combination with SIEMENS MAGNETOM SCANNERS.
The Receiver will remain fully responsible for their PRODUCTS including
the combination with the SIEMENS MAGNETOM SCANNER, and the manufacture,
sale, marketing and service of the PRODUCTS. SIEMENS
however endeavors to provide complete and accurate INFORMATION.

 

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		7.1.5	SIEMENS is not responsible for an infringement
of any third party intellectual property rights due to: (i) The Receiver’s failure to use the most current version of or
a defect correction or patch supplied by SIEMENS for the DEVELOPER SERVICES, the
SDK or the INTERFACE; (ii) the combination, operation, or
use of the DEVELOPER SERVICES; the SDK or the INTERFACE in conjunction with any Receiver content or with any third-party
software, equipment, materials,
or products; or (iii) an adjustment or configuration of the DEVELOPER SERVICES; the SDK or the INTERFACE not made by, or
on behalf of, SIEMENS or its AFFILIATES (or as contemplated by Section 7.1.7);
provided always that the DEVELOPER SERVICES, SDK or the INTERFACE
as supplied by SIEMENS are not the root cause for such infringement. Notwithstanding
any deviating and/or additional obligations expressly set forth in the Agreement, SIEMENS will neither assume any additional obligation
nor responsibility that the DEVELOPER SERVICES, the SDK or the
INTERFACE and/or the Receiver’s use of the DEVELOPER SERVICES, the SDK or the INTERFACE comply with applicable law.

 

		7.1.6	This Agreement does not cover service
related issues for either party at the Receiver’s site or at the END USER’s site and SIEMENS is not responsible for
any service or support related to the Receiver’s PRODUCTS and the combination of the PRODUCTS to the SIEMENS MAGNETOM SCANNER
unless otherwise agreed upon in writing.

 

		7.1.7	SIEMENS may engage any of its AFFILIATES
and any other business partners for and in connection with the provision of DEVELOPER SERVICES, the
AUTHORIZATION KEY, INTERFACE, billing
or payment. The Receiver agrees to provide all reasonable cooperation
required by SIEMENS should it become necessary or desirable, in
SIEMENS’ sole discretion, for SIEMENS to use a new or different
service providers. SIEMENS will be responsible for any of its obligations hereunder which are performed by its AFFILIATES,
business partners and other service providers.

 

		7.1.8	The Receiver may, without
accounting to SIEMENS, use and modify information and documentation
in order to generate its END USER documentation of the PRODUCTS and the combination of the PRODUCTS to the SIEMENS MAGNETOM SCANNER,
provided this is done:

 

		•	at the Receiver’s own cost, responsibility and risk,

		•	ensuring that the documentation conforms
to the regulations applicable in the target countries and continuously updating it to the newest revision level, in
particular as such information and documentation provided by SIEMENS may be country or region-specific
and subject to change,

		•	without in any way portraying SIEMENS
as responsible for the content of the END USER documentation, and
clearly identifying the Receiver as responsible for marketing, sale,
market-observation
and service, subject to customary disclaimers and limitation on liability.

 

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	 	7.2	The
                                         Receiver agrees to:
	 	 	 
		7.2.1	Generate
                                         and provide all END USER documentation.

 

		7.2.2	Complete risk assessments, risk mitigation,
integration and system testing, compatibility
testing, etc. for their PRODUCTS and comply with all applicable
statutory provisions and regulations (e.g. those
stipulated by the FDA or the European Commission or Japanese equivalent regulatory bodies) of the target country in which the combined
product will be operated before releasing the PRODUCT into the market. Upon
SIEMENS discretion which will not be unreasonably withheld, SIEMENS
will use commercially reasonable efforts to provide standard documentation and reasonable support in connection with such activities
upon request.

 

		7.2.3	Ensure that the Receiver’s END-USER’s
are provided with all reasonably relevant instructions, warnings and, if
required, training for the Receiver’s PRODUCTS and its combination
with the SIEMENS MAGNETOM SCANNERS, particularly if these are safety-relevant.

 

		7.2.4	The Receiver is responsible for post market
surveillance (as required by applicable laws and regulations where Receiver’s PRODUCTS are approved and in use) of their
PRODUCTS and the combination of their PRODUCTS with SIEMENS MAGENTOM SCANNERS.

 

Furthermore,
the Receiver has the responsibility for the proper handling and, in case of adverse events, reporting to regulatory bodies customer
complaints related to the combination of their PRODUCTS to the SIEMENS MAGNETOM SCANNERS (as required by applicable laws and regulations
where Receiver’s PRODUCTS are approved and in use).

 

The
Receiver has the obligation to inform SIEMENS without undue delay about material adverse events in relation to the combination
of their PRODUCTS and the SIEMENS MAGNETOM SCANNER to the best of the Receiver’s knowledge.

 

The Receiver has the responsibility
to perform field updates and recalls, if necessary conduct reporting to reduce a risk to health and bring back the combination
into specification.

 

SIEMENS will not take any responsibility
related to post market surveillance / vigilance of the combination of the Receiver’s PRODUCTS with the SIEMENS MAGNETOM
SCANNERS other than as set out in Section 4.

 

		7.3	The Receiver shall indemnify, defend
and hold harmless SIEMENS and its AFFILIATES from any and all proceedings, costs,
expenses, damages, fees, penalties, and losses (including reasonable attorney fees), in
each case arising from a third party claim, that result from:

 

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		7.3.1	A culpable breach of an obligation under this Agreement by the Receiver, Receiver’s AFFILIATES
and their respective employees and agents; and

 

		7.3.2	failures of the SIEMENS MAGNETOM SCANNERS
to function in accordance with their INFORMATION to the extent caused by the combination of the Receiver’s PRODUCTS with
SIEMENS MAGNETOM SCANNERS.

 

		7.4	SIEMENS shall indemnify, defend
and hold harmless Receiver and its AFFILIATES from any and all proceedings, costs,
expenses, damages, fees, penalties, and losses (including reasonable
attorney fees), in each case arising from a third party claim,
that result from:

 

		7.4.1	A non-fulfillment,
wrongful act or omission or a culpable breach of an obligation under this
Agreement by SIEMENS, SIEMENS AFFILIATES and their respective employees
and agents; and

 

		7.4.2	failures of the SIEMENS MAGNETOM SCANNERS,
the INTERFACE, or
the SDK to function in accordance with their INFORMATION to the extent they are not caused by the combination of the Receiver’s
PRODUCTS with SIEMENS MAGNETOM SCANNERS, the INTERFACE,
or the SDK; and

 

		7.4.3	a claim that the SIEMENS MAGNETOM SCANNERS,
the INTERFACE, or
the SDK infringe or misappropriate an OTHER’s IP other than where such infringement or misappropriation would not have occurred
but for the combination of the SIEMENS MAGNETOM SCANNERS, the INTERFACE,
or the SDK with the PRODUCT.

 

Article
8 - Billing

 

The
services and responsibilities described under this Agreement make SIEMENS eligible to receive a yearly license fee calculated as
outlined in Article 6.3. The
invoices will refer to an applicable timeframe. Receiver will pay
all properly invoiced amounts within 30 days of its receipt of
the applicable invoice.

 

The
license fee will be paid in US currency to SIEMENS or its respective AFFILIATES. Each
PARTY will ensure that its AFFILIATES adopt and comply with the provisions of this Agreement applicable to such transactions to
the extent allowed under local law.

 

Within
thirty (30) business days after the end of each calendar quarter, SIEMENS
will invoice the Receiver the license fee for the applicable quarter as defined in Article 6 - Pricing
based on all connected SIEMENS MAGNETOM SCANNERS and based on the analysis of the received customer data; the number of issued
AUTHORIZATION KEYS and the resulting license fee and prorated for the applicable portion of the quarter.

 

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lf
the Receiver is required by law to make any deduction or to withhold from any sum payable directly to SIEMENS or any of its AFFILIATES
hereunder, the Receiver shall promptly effect payment thereof to
the applicable tax authorities, and shall also promptly provide SIEMENS or any of its AFFILIATES with official tax receipts or
other evidence sufficient to establish that the taxes have been paid and to enable SIEMENS or any of its AFFILIATES to support
a claim for income tax credits for such payments. Failure to provide official tax receipts or other evidence of payment shall
result in the Receiver paying directly to SIEMENS or any of its AFFILIATES such amounts deducted or withheld from the original
payment. The Receiver shall also assist SIEMENS or any of its AFFILIATES in minimizing the withholding rate available under an
applicable tax treaty, or otherwise, by supplying SIEMENS or any
of its AFFILIATES with any appropriate documentation upon reasonable request.

 

Article
9 - Marketing

 

SIEMENS
may, but is not obligated to, advertise
the PRODUCTS offered by the Receiver. For this purpose, the Receiver grants SIEMENS a non-exclusive,
non-transferable,
sub-licensable,
and royalty-free worldwide license to use all trademarks or trade
names of the Receiver’s PRODUCTS.

 

RECEIVER
may, but is not obligated to, advertise the combination of SIEMENS
MAGNETOM SCANNERS and the Receiver’s PRODUCTS.

 

All
such advertising materials created by either PARTY using any trademark or trade names of the other PARTY will be subject to prior
approval, not to be unreasonably withheld or delayed.

 

The
PARTIES will discuss in good faith the possibilities for a joint marketing collaboration between the PARTIES, aiming
towards each of the PARTIES being able to market a joint offering of the PRODUCTS together with SIEMENS MAGNETOM SCANNERS.
Any such expanded collaboration shall be agreed upon separately between
the PARTIES.

 

Article 10 - Monitoring of Usage Data

 

SIEMENS
may and will use reasonable efforts to monitor the usage of the INTERFACE by END USERS, e.g.,
the number of users, for SIEMENS’ internal business purposes,
in particular: (i) for security and availability reasons; (ii) to the extent required to ensure compliance of the END USER with
the applicable END USER agreement and of the Receiver with this Agreement; and (iii) to detect, prevent,
and suspend any use of the INTERFACE exceeding the permitted use under the END USER agreement as well as this Agreement,
to charge for such excess use, and otherwise as necessary for payment
and billing related tasks.

 

Article 11 - Suspension of the AUTHORIZATION
KEY and LICENSE KEY

 

SIEMENS
is entitled to suspend the AUTHORIZATION KEY for the INTERFACE issued to the Receiver at any time, resulting
in the END USER no longer being able to use the Receiver’s PRODUCTS, if
in SIEMENS’ reasonable judgment there is a risk that the use of the Receiver’s PRODUCT by the END USER will: (i) constitute
a threat to the security or functionality of the END USER’S systems;(ii) adversely impact the END USER, the
Receiver, SIEMENS, the Receiver’s or SIEMENS’ AFFILIATES,
or any third party, including,
without limitation, any risk of personal injury; [or (iii) subject
the END USER, the Receiver, SIEMENS, the
Receiver’s or SIEMENS’ AFFILIATES, or any third party
to liability for personal injury or IP infringement]. Furthermore, SIEMENS
is entitled to suspend the LICENSE KEY if such revocation is required by law, a
court decision, or a request from a governmental body; and (iii) SIEMENS is entitled to revoke the END USER LICENSE KEY for the
relevant END USER if, in each case for security or compliance reasons
or requests from a governmental body, its access to the INTERFACE has been suspended or the agreement between SIEMENS and the END USER has been terminated by SIEMENS or the END USER.
SIEMENS will, whenever
reasonably possible, consult with Receiver in advance of the revocation
of a LICENSE KEY. SIEMENS will inform the Receiver about any revocation
of a LICENSE KEY as soon as possible. SIEMENS will reinstate any
suspended AUTHORIZATION KEY or LICENSE KEY once the circumstances giving rise to such suspension have been remedied.

 

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Article 12 - Notification Page

 

SIEMENS
is entitled to notify the Receiver, END USERS, and
authorities in a suitable form at any time, if: (i) in SIEMENS’
reasonable judgment there is a risk that the use of the Receiver’s PRODUCTS by the END USER will: (a) threaten the security
or functionality of the END USER’s systems; (b) adversely impact the END USER or any third party, including,
without limitation, any
risk of personal injury; or (c) subject the END USER or any third party to liability for personal injury or IP infringement; or
(ii) such notification is required by law, a court decision, or
a request from a governmental body; provided that SIEMENS will notify Receiver prior to providing any such notice to END USERS
or authorities.

 

The
Receiver acknowledges that a revocation of the AUTHORIZATION KEY or the LICENSE KEY pursuant to and in compliance with the conditions
of Article 11 - or a notification pursuant to and in compliance
with this Article by SIEMENS does not lead to any responsibility of SIEMENS.

 

Article 13 - Support

 

Where
END USERS contact SIEMENS for support queries, SIEMENS will: (i)
process queries concerning the SIEMENS MAGNETOM SCANNERS and provide all support with respect to the SIEMENS MAGNETOM SCANNERS;
and (ii) forward queries concerning the Receiver’s PRODUCT to the Receiver within a reasonable period of time and the Receiver
(and not SIEMENS) will have responsibility for providing the support. Upon
receipt, the Receiver will forward support queries from END USERS
concerning the SIEMENS MAGNETOM SCANNER to SIEMENS within a reasonable period of time. Each
PARTY may notify the other PARTY of changes to its point of contact at least two (2) weeks in advance, e-mail
being sufficient.

 

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Article 14 - Liability

 

		14.1	The PARTIES agree that other than as set
out in this Agreement: any information is made available “as is” and no warranties are given or liabilities of any
kind are assumed with respect to the quality of such information, including, but
not limited, to its fitness for the purpose, non-infringement
of third-party rights, its correctness or completeness. Furthermore,
none of the Parties’ obligations under this Agreement shall be deemed
to constitute a guaranteed quality or other guarantee. In addition, other
than as expressly set out in this agreement, each of the Parties
disclaims any strict liability for defects and non-conformance already existing when this contract was concluded.

 

		14.2	This clause 14 sets out the entire financial
liability of each of the PARTIES (including any liability for the acts or omissions of its AFFILIATES, employees,
agents, consultants and subcontractors) under this Agreement, including
in respect of any breach and any representation, statement or tortious act or omission (including negligence), indemnity,
warranty, or
strict liability arising under or in connection with this Agreement.

 

		14.3	Subject to clause 14.4
the liability of each PARTY under this Agreement shall be limited to direct losses and only to an amount of EUR 250,000-
for each single damage event and subject to a maximum of EUR 1,000,000-
for all such events. Claims for other indirect losses, including
but not limited to claims for business stoppage, indirect lost profit, loss
of information or data as well as consequential, special or incidental
losses shall be excluded regardless of their legal grounds.

 

		14.4	This disclaimer of liability shall not
apply in cases involving intent or gross negligence, or where liability is mandatory by law.

 

		14.5	The Receiver will, in
its sole responsibility, decide on the use of the INTERFACE,
the SDK, the
DEVELOPER SERVICES, the INFORMATION or any other material provided
through SIEMENS. SIEMENS does not assume any liability for defects
of or damages to the END USER’S systems resulting from the use of the INTERFACE, the
SDK, the DEVELOPER SERVICES, the
INFORMATION or any other material provided through SIEMENS and hereby waives and excludes any and all liability arising out of
or in connection with the use of the INTERFACE, the SDK,
the DEVELOPER SERVICES, the
INFORMATION or any other material provided through SIEMENS beyond the intended use whether based on contract, tort,
negligence, under an indemnity, warranty,
strict liability or otherwise except to the extent such defect or damage
is caused or contributed to by a negligent act or negligent omission of SIEMENS, or a breach of this Agreement.

 

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		14.6	Subject to of the INTERFACE, the
SDK, the DEVELOPER SERVICES, the
INFORMATION or any other material provided through SIEMENS or its AFFILIATES is the responsibility of the Receiver.

 

Article 15 - Confidentiality

 

		15.1	“CONFIDENTIAL INFORMATION”
shall mean any information and data, including without limitation,
any kind of business, commercial
or technical information and data disclosed by the Receiver to SIEMENS or SIEMENS to the Receiver in connection with the execution
or performance of this Agreement, irrespective of the medium in
which such information or data is embedded, which is:

 

		·	when disclosed in tangible form –
marked “Confidential” by the disclosing PARTY

		·	or when disclosed orally or visually –
identified as such prior to disclosure and summarized in writing by the disclosing PARTY and said summary is given to the receiving
PARTY within thirty (30) days after such disclosure marked “Confidential”. In case of disagreement regarding orally
or visually disclosed information, the receiving PARTY must present
its objections to the summary in writing within thirty (30) days
of receipt

 

CONFIDENTIAL
INFORMATION shall also include any copies or abstracts made thereof as well as any apparatus, data,
modules, samples, prototypes or parts thereof.

 

For
the avoidance of doubt, the pricing information described in Article
6.1 and Article 6.3, the library of examples, the SDK, the
INTERFACE description shall deemed to be SIEMENS CONFIDENTIAL INFORMATION irrespective of the fact if they are marked or not.
All information about the PRODUCTS or Receiver’s business practices
which is not made generally available to the public and the pricing information described in Article 6.1
and Article 6.3 shall be deemed Receiver CONFIDENTIAL INFORMATION.

 

		15.2	The receiving PARTY shall maintain CONFIDENTIAL
INFORMATION received from the disclosing PARTY in confidence and will use such CONFIDENTIAL INFORMATION solely for the purposes
of this Agreement, and shall not distribute or disclose it,
provided, however,
that the receiving PARTY may disclose such information to its officers,
AFFILIATES, and those of its employees and subcontractors who need
to know it for the purposes of this Agreement. Each PARTY shall
impose on its officers, AFFILIATES, and its employees and subcontractors
confidentiality obligations no less stringent than its own confidentiality obligations under this Agreement, and
the receiving PARTY will be responsible for any violation of the confidentiality obligations under this Agreement by any of its
officers, AFFILIATES, employees
or subcontractors.

 

		15.3	The obligations of Article 15.2 shall
remain in force for a period of five (5) years after the termination of this Agreement. CONFIDENTIAL
INFORMATION (as defined in the Original Agreement) disclosed by either PARTY under the Original Agreement shall be deemed CONFIDENTIAL
INFORMATION disclosed under this Agreement and shall be subject to the provisions of this Article 15.

 

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		15.4	The obligations of Article 15.2
shall not apply to information which is or becomes generally known to the public or which has been obtained independently as evidenced
by a PARTY’S business records or acquired legitimately from OTHERS who are to the knowledge of the receiving PARTY free to
lawfully disclose the information.

 

		15.5	The provisions of Article 15.2
hereof shall apply to copies of electronically exchanged CONFIDENTIAL INFORMATION made as a matter of routine information technology
backup and to CONFIDENTIAL INFORMATION or copies thereof which must be stored by the receiving PARTY or its advisers according
to provisions of mandatory law or as required by regulatory bodies such as the FDA, and
such CONFIDENTIAL INFORMATION or copies thereof shall be subject to an indefinite confidentiality obligation according to the terms
and conditions set forth herein.

 

		15.6	Save as set out in Article 15.5
above, within ninety (90) calendar days after termination of this
Agreement, the receiving PARTY shall destroy or, as may be requested
by the disclosing PARTY, return all CONFIDENTIAL INFORMATION received
and stored electronically and/or on record-bearing media as well
as any copies thereof. The receiving PARTY shall confirm in writing such destruction to the disclosing PARTY. Excluded
from the obligations set out in this Article 15.6 is information that the Receiver is required to retain in his technical files
relating to the PRODUCTS or information that: (a) is required to enforce or comply with the terms of this Agreement or Receiver’s
agreements with End Users; or (b) is stored in accordance with a Party’s back-up and disaster recovery systems.

 

Article
16 - Agreement Term, Notification and CHANGE-OF-CONTROL

 

		16.1	This Agreement shall come into force when
signed by both PARTIES and shall have a term for sixty (60) months.
Unless earlier terminated, the Agreement shall be extended for
successive terms of one (1) year each unless written notice to terminate is given by either PARTY at least three (3) months before
the end of the respective contract term.

 

		16.2	Each PARTY shall be entitled to terminate
this Agreement prematurely by means of written notice, if the other
PARTY breaches a material obligation and fails to rectify the aforesaid breach within ninety (90)
calendar days of the non-breaching PARTY’s notice.

 

		16.3	If there is a CHANGE-OF-CONTROL to a COMPETITOR of SIEMENS:

		•	the Receiver shall inform SIEMENS in writing within fifteen (15) calendar days, but under no circumstance
later than any public announcement by the Receiver,

 

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		•	The PARTIES shall discuss in good faith
within thirty (30) calendar days after SIEMENS has been informed
in writing by the Receiver,

		•	In particular, it
shall be discussed how such CHANGE OF CONTROL would impact the relationship contemplated by this Agreement, including
whether the Receiver or such COMPETITOR will terminate this Agreement after the closing of such CHANGE OF CONTROL transaction,
and

		•	SIEMENS shall be entitled to terminate
with immediate effect this Agreement within sixty (60) calendar
days after SIEMENS has been informed in writing by the Receiver of such CHANGE OF CONTROL involving a COMPETITOR of SIEMENS,
provided that SIEMENS, acting reasonably, shall only terminate this Agreement
if such CHANGE OF CONTROL transaction involving a COMPETITOR of SIEMENS will have a detrimental impact on the PARTIES collaboration
hereunder relating to the PRODUCTS and SIEMENS MAGNETOM SCANNERS.

 

		16.4	The provisions in Article 7 - ,
Article 10 - Article
11 - Article 12 - Article
14 - this Article 16.4
and Article 19 - shall survive the expiration or termination of
this Agreement. With regards to the PRODUCTS which have already been connected to SIEMENS MAGNETOM SCANNERS before expiration or
termination of this agreement the licenses granted for the AUTHORIZATION KEY shall be unaffected as well as the corresponding obligation
to pay the license fee as set forth in Article 2, Article 6 and
Article 8 for all granted AUTHORIZATION KEYs., unless and until
such time as Receiver specifies which individual or all such AUTHORIZATION KEYS are no longer in use. Then the Receiver only has
the obligation to pay the license fee for all the AUTHORIZATION KEYs still in use.

 

Article 17 - Force Majeure

 

		17.1	A PARTY shall not be in breach of this
Agreement, nor liable for any failure or delay in the performance
of any of its obligations under this Agreement as a result of force majeure event provided that:

 

		17.1.1	it promptly notifies the other PARTY in writing of the nature and extent of the force majeure event
causing its failure or delay in performance; and

 

		17.1.2	it has used reasonable endeavors to mitigate
the effect of the force majeure event, to carry out its obligations
under this Agreement in any way that is reasonably practicable and to resume the performance of its obligations as soon as reasonably
possible.

 

		17.2	‘Force majeure event’ in the sense of this Agreement shall be one of the following
events which is outside the control of a PARTY and its suppliers and contractors and prevents that PARTY from meeting its contractual
obligations:

 

		17.2.1	acts of God, fires, floods,
earthquakes or other natural disasters;

 

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		17.2.2	war, embargo, terrorist
attack, riots;

 

		17.2.3	explosion or building collapse;

 

		17.2.4	failure of plant machinery, interruption
or failure of utility service, including but not limited to electric power, gas
or water.

 

		17.3	If either PARTY is prevented from meeting
its obligations under this Agreement for a continuous period of more than six (6) months as a result of a ‘force majeure
event’, the other PARTY shall be entitled, at its sole discretion,
to terminate the Agreement with one (1) month’s written notice.

 

Article 18 - Miscellaneous

 

		18.1	Neither PARTY shall be entitled, without
the prior written consent of the other, to transfer or assign this
Agreement or any rights and obligations arising from it to OTHERS, except
a transfer or assignment to an AFFILIATE or a purchaser of substantially all of the assets of a PARTY, provided
that the transferring or assigning PARTY shall remain responsible for the fulfilment of the obligations it originally incurred
under the Agreement. Consent hereto shall not be unreasonably withheld.

 

		18.2	SIEMENS’ obligation to fulfill this Agreement is subject to the proviso that the fulfillment
is not prevented by any impediments arising out of national and international foreign trade and customs requirements or any embargos
or other sanctions.

 

		18.3	The PARTIES shall comply with all applicable
export control, customs and foreign trade regulations (“Foreign
Trade Regulations”) and shall obtain all necessary export licenses, if any.

 

		18.4	Any amendments as well as supplements
to this Agreement must be in writing and signed by the PARTY to be bound in order to be effective. A
waiver of form shall be effective only if agreed upon in writing and signed by the PARTY to be bound.

 

		18.5	If this Agreement requires a notice or
a document to be „in writing” or „in written form”, such notice or document shall be duly signed by the
sender and the signed notice or document shall be delivered, sent
or transmitted to the other PARTY in its original form or as a telefax copy or a PDF. For the avoidance of doubt, electronic
communication shall not qualify as a written notice or document unless confirmed as received by the receiving PARTY.

 

		18.6	Any general terms and conditions of the
PARTIES in addition to this Agreement shall be excluded. This shall
particularly apply if there is any reference to such terms in correspondence or other documentation of the PARTIES (e.g.,
printed, stamped
and electronically reproduced).

 

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		18.7	If any provisions of this Agreement should
be held to be illegal, invalid or unenforceable, the
validity, legality and enforceability of the remaining provisions
shall not in any way be affected or impaired thereby. The PARTIES
shall substitute the illegal, invalid, or unenforceable provision
by a legal, valid or enforceable one, approximating
as closely as possible the original commercial intent of the PARTIES.

 

		18.8	If provisions of this Agreement conflict
with the Annexes or other agreements, the provisions of this Agreement
shall have precedence.

 

		18.9	The Original Agreement and the PARTIES’
obligations thereunder are hereby terminated and replaced by this Agreement. [Article
7.2 of the Original Agreement shall continue to apply after the
Effective Date of this Agreement; provided that Art. 8 of the Original
Agreement shall not survive termination of the Original Agreement according to this section 18.9.

 

Article 19 - Arbitration and Substantive
Law

 

		19.1	If a dispute arises in connection with
this Agreement, the responsible representatives of the PARTIES
shall attempt, in fair dealing and good faith, to settle such dispute.
Upon request of a PARTY a senior management representative of each PARTY shall participate in the negotiations. Each PARTY shall
be entitled to terminate these negotiations by written notification to the other PARTY at any time.

 

		19.2	The PARTIES shall attempt to agree on
a procedure for Alternative Dispute Resolution (ADR) and the applicable procedural rules (including time limits) within fourteen
days after a termination notice under Article 19.1 has been received by the other side. If the PARTIES fail to agree on such procedure
within this time limit each PARTY shall be entitled to refer the dispute to arbitration pursuant to Article 19.3.

 

		19.3	All disputes arising in connection with
this Agreement which are not resolved pursuant to Article 19.1
or an ADR procedure, including any question regarding the termination or any subsequent amendment of the Agreement, shall
be finally settled in accordance with the Rules of Arbitration (“Rules”) of the International Chamber of Commerce (“ICC”).
The seat of arbitration shall be Zurich Switzerland. The
language to be used in the ADR and the arbitration proceeding shall be English. Any
production of documents shall be limited to the documents on which each PARTY specifically relies in its submission(s). Consolidation
of arbitrations pending under the Rules into a single arbitration shall only be possible if the PARTIES have agreed to consolidation.
The unsuccessful PARTY shall bear the costs of the arbitral proceedings.
However, the arbitral tribunal may take into account the extent to which
each PARTY has conducted the arbitration in an expeditious and cost-effective
manner.

 

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		19.4	This Agreement shall be subject to the substantive law in force in Germany without reference to
any of its conflict of law rules.

 

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..............

 

	Place, Date:	 	 
	 	 	 
	Mississauga, Ontario, February 11, 2019	 	 
	 	 	 
	/s/ Aaron Davidson	 	/s/ Arun Menawat
	 	 	 
	Name (Print):	 	Name (Print):
	Aaron Davidson	 	Arun Menawat
	 	 	 
	Title:	 	Title:
	Chief Financial Officer	 	Chief Executive Officer
	 	 	 
	SIEMENS Healthcare GmbH	 	 
	 	 	 
	Place, Date:	 	 
	 	 	 
	Erlangen, Germany, January 23, 2019	 	 
	 	 	 
	/s/ Dr. Robert Krieg	 	/s/ Peter
    Horn
	 	 	 
	Name (Print):	 	Name (Print):
	Dr. Robert Krieg	 	Peter Horn
	 	 	 
	Title:	 	Title:
	VP MR Advanced Solutions & Therapy	 	Senior Vice President Finance
	 	 	Magnetic Resonance

 

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Annex 1

 

Specification of INFORMATION

 

Preamble

 

SIEMENS provides the INFORMATION to the Receiver for the sole
purpose of interfacing the PRODUCTS to certain SIEMENS MAGNETOM SCANNERS and to deliver such adapted PRODUCTS to END USERS for
interworking with SIEMENS MAGNETOM SCANNERS. The INFORMATION in scope are described in this Annex.

 

Interface description

 

Access-I
developer guide with comprehensive documentation of the interface, intended for a developer to integrate against this interface.
Includes descriptions of the setup, configuration, methods of
the interface with examples.

 

Software Development Kit (SDK)

 

A
test environment is provided to ease the development, integration and testing of remote clients with Access-i. It comprises
an Access-I Simulator and a Test Client, which are designed
for a Windows PC environment.

 

The Access-i Simulator enables the remote client implementation
and testing without the need for physical access to an MR scanner. It mimics the Access-I related functionality of the MR host

 

The Access-i
Test Client provides an example implementation of a
remote client, and also serves as a reference to verify the functionality of the Access-i interface.

 

Source Code toolbox

As part of the SDK, some source code toolboxes are included
to provide an example implementation of a remote client. These can be used in the development of the remote client to enable faster
development

 

     

     

    

 

Annex 2

 

Specification of PRODUCTS

 

Preamble

 

SIEMENS
provides the INFORMATION to the Receiver for the sole purpose of interfacing the PRODUCTS to certain SIEMENS MAGNETOM SCANNERS
and to deliver such adapted PRODUCTS to END USERS for interworking with SIEMENS MAGNETOM SCANNERS. The PRODUCTS in scope are described
in this Annex.

 

Product Name

 

TULSA-PRO

 

Sonalleve

 

Product Description

 

TULSA-PRO: MRI guided directional ultrasound ablation of soft
tissue

 

Sonalleve:
MRI guided high-intensity focused ultrasound of soft tissue, bone
and nerves

 

Intended Use

 

TULSA-PRO: MRI guided directional ultrasound ablation of soft
tissue

 

Sonalleve: MRI guided high-intensity focused ultrasound of soft
tissue, bone and nerves

 

     

     

    

 

Regulatory Status and Regulatory Roadmap

 

TULSA-PRO: Approved in EU and soon to be in registration in
the US

 

Sonalleve:
Approved in the EU, and several Asian countries including
China and soon to be in registration in the US

 

MR-Compatibility Status

 

TULSA
-PRO: Intention is to be compatible with all Siemens scanners upon which
Access I can be operational

 

Sonalleve: Intention is to be compatible with all Siemens scanners
upon which Access I can be operational

 

     

     

    

 

Annex 3

 

Agreement for risks exported in using
Access-i

 

Preamble

 

Siemens Healthcare GmbH has created a risk analysis according
to their risk management process fulfilling the requirements given by IS014971:2012. Listed below are the residual risks related
to the use of “Access-i” interface that cannot be further mitigated by Siemens Healthcare GmbH and which the Receiver
accepts in using this interface functionality. It is the responsibility of the Receiver to ensure that the appropriate measures
are in place to mitigate these risks in using this’ interface functionality.

 

Risks exported to the Receiver using the Access-i interface:

 

	No	 	Function 	 	Error	 	Cause	 	Hazard	 	Measure(s)
	 	 	 	 	 	 	 	 	 	 	 
	1	 	 	 	NUMARIS/4 product SW crash or instability, loss
    in performance.	 	SW hang-up / Side effects / secondary effects on NUMARIS/4 product SW	 	Delayed diagnosis	 	It must be ensured, that the status of the MR system always corresponds to the required status (e.g. sequence is running) during safety relevant interventions
	2	 	Remote PC- control session active	 	
        No fast way to stop the MR measurement and/or patient table
        movement in an emergency situation.

         

        Visual and audio contact to the patient (window / video / Intercom
        system (cf. above)) not possible.
	 	The patient intercom system / video supervision remains at the MR AWP and is not available at the remote PC.	 	Various!	 	Patients must be monitored, always and it needs to be ensured that MR measurement can be stopped in emergency situations.
	3	 	 	 	Connection between MR AWP and remote PC gets lost.	 	Technical defect; Forced control take over at the MR AWP (e.g. by User); Remote session is aborted (intended or unintended)	 	Burns up to 2nd degree; misdiagnosis; Jamming or injection / infusion needles pulled out – minor or moderate injury	 	A termination or a break of the connection between the MR AWP and the remote PC must be recognized. In this case the procedure (e.g. intervention) must be handled appropriately (e.g. stopped).
	4	 	 	 	Parameters are accidently changed on the MR AWP	 	Access to MR System by MR AWP between two remote control sessions possible.	 	Delayed diagnosis	 	It must be ensured that the protocol parameters are not changed unintentionally before each procedure (e.g. intervention). Only Personnel that are trained must use the MR-Device and the remote PC. It is recommended to have at least two persons for the workflow.
	5	 	Remote PC – Untrained Personnel	 	MR device not used correctly	 	Untrained personnel are using the MR Device (via remote control)	 	Various!	 	Only Personnel which are trained must use the MR-Device and the remote PC. It is recommended to have two persons for the workflow.
	6	 	Remote PC – Popup Issue service	 	Popup confirmed (automatically) by remote PC SW	 	Malfunction of remote PC software or intended automated popup confirmation.	 	Misdiagnosis	 	The remote PC SW must consider all popup related information provided by MR AWP via the issue service for safe and proper use of the MR Device; e.g. automatic table movement. Popups can be handled automatically by SW, if the consequences are known and measures are implemented to prevent resulting hazards.
	7	 	Remote PC – Debugging service	 	Start of savelog generation shortly before a sequence is started	 	Savelog generation can take up to 5 minutes and can lead to a longer reconstruction time	 	Delayed diagnosis	 	If update rate of date is not sufficient for the required application the procedure (e.g. intervention) must be handled appropriately (e.g. stopped).
	8	 	Remote PC – Image Service	 	Image service and/or projection service not available	 	Automatic receive of images via websocket functionality	 	Delayed diagnosis	 	If update rate of date is not sufficient for the required application the procedure (e.g. intervention) must be handled appropriately (e.g. stopped).Exhibit 4.7

 

EXECUTION COPY

 

CREDIT AGREEMENT

 

between 

 

PROFOUND MEDICAL INC.

as Borrower

 

AND

 

PROFOUND MEDICAL CORP. 

PROFOUND MEDICAL GMBH 

PROFOUND MEDICAL (U.S.) INC.

as Guarantors

 

AND

 

CANADIAN IMPERIAL BANK OF COMMERCE

as Lender

 

 

 

dated as of 

 

July 30, 2018

 

GOODMANS LLP

 

     

     

    

 

TABLE OF CONTENTS

 

	ARTICLE I. INTERPRETATION	1
	Section 1.01	Definitions	1
	Section 1.02	PPSA	20
	Section 1.03	Headings	20
	Section 1.04	References to Sections	20
	Section 1.05	Currency	20
	Section 1.06	Gender and Number	20
	Section 1.07	Invalidity of Provisions	20
	Section 1.08	Transition from GAAP to US GAAP	20
	Section 1.09	Amendment or Waiver	21
	Section 1.10	Non-Business Days	21
	Section 1.11	Currency Equivalents	21
	Section 1.12	German Terms	21
	 	 	 
	ARTICLE II. THE LOANS	22
	Section 2.01	The Commitments	22
	Section 2.02	Loans	22
	Section 2.03	Fees	23
	Section 2.04	Payment; Computation	24
	Section 2.05	Loan Account	24
	 	 	 
	ARTICLE III. PAYMENTS AND PREPAYMENTS	24
	Section 3.01	Repayment of Loans	24
	Section 3.02	Interest	24
	Section 3.03	End of Term Payment	26
	Section 3.04	Optional Prepayments	26
	Section 3.05	Mandatory Prepayments	26
	Section 3.06	Application of Prepayments	27
	Section 3.07	Notice of Prepayments	27
	Section 3.08	Payments Generally	28
	Section 3.09	Change in Law and Increased Costs	28
	Section 3.10	Taxes	29
	Section 3.11	Illegality	31
	 	 	 
	ARTICLE IV. SECURITY	31
	Section 4.01	Security Documents	31
	Section 4.02	Control of Collateral; Control Agreements	32
	Section 4.03	Guarantors	33
	Section 4.04	Real Estate	33
	Section 4.05	Delivery of Additional Documentation Required	33
	Section 4.06	Right to Inspect	34

 

    - i -

     

    

 

	ARTICLE V. REPRESENTATIONS AND WARRANTIES 	34
	Section 5.01	Incorporation and Status	34
	Section 5.02	Corporate Power and Due Authorization	34
	Section 5.03	Business of the Loan Parties	34
	Section 5.04	No Contravention	35
	Section 5.05	Not Insolvent	35
	Section 5.06	Approvals and Consents	35
	Section 5.07	Welfare and Pension Plans	35
	Section 5.08	Changes Since Date of Financial Statements	35
	Section 5.09	No Default Under Agreements	36
	Section 5.10	Title to Assets	37
	Section 5.11	Financial Matters	37
	Section 5.12	No Material Adverse Change	37
	Section 5.13	Environmental Matters	37
	Section 5.14	Assets in Good Condition	38
	Section 5.15	Licenses and Agreements	38
	Section 5.16	Tax Matters	38
	Section 5.17	Insurance	38
	Section 5.18	Intellectual Property	39
	Section 5.19	Permits	39
	Section 5.20	Regulatory Required Permits	39
	Section 5.21	Compliance with Laws and Litigation	40
	Section 5.22	Material Facts Disclosed	40
	Section 5.23	No Rights to Acquire Assets	40
	Section 5.24	No Rights to Provide Financial Advisory Services	40
	Section 5.25	Chief Executive Office and Location of Assets	40
	Section 5.26	Minute Books	41
	Section 5.27	Use of Proceeds; Margin Stock	41
	Section 5.28	Investment Company Act	41
	Section 5.29	Bank Accounts	41
	Section 5.30	Shares and Corporate Structure	41
	Section 5.31	Liabilities	42
	Section 5.32	Employee Matters	42
	Section 5.33	Non-Arm’s Length Transactions	43
	Section 5.34	Description of Real Property	43
	Section 5.35	Application of Section to New Subsidiaries	43
	 	 	 
	ARTICLE VI. COVENANTS 	43
	Section 6.01	Use of Proceeds	43
	Section 6.02	Payment of Principal and Interest; Secured Obligations	43
	Section 6.03	Lender Expenses	44
	Section 6.04	Compliance with Laws; Permits; Corporate Existence	44
	Section 6.05	Delivery of Collateral and Perfection	44
	Section 6.06	Collateral	44

 

    - ii -

     

    

 

	Section 6.07	Operating Leases	44
	Section 6.08	Insurance	44
	Section 6.09	Transactions with Affiliates	45
	Section 6.10	Material Agreement	45
	Section 6.11	Reporting	45
	Section 6.12	Healthcare Regulatory Matters	45
	Section 6.13	Accounts	46
	Section 6.14	Negative Covenants	46
	Section 6.15	Maintenance of Records	47
	Section 6.16	Notices	48
	Section 6.17	Limitations on Modifications, Waivers, Extensions	48
	Section 6.18	Financial Covenant	48
	Section 6.19	Intellectual Property	49
	Section 6.20	Pension Plans	50
	Section 6.21	Material Subsidiaries	50
	Section 6.22	Centre of Main Interests	50
	 	 	 
	ARTICLE VII. CONDITIONS 	51
	Section 7.01	Conditions Precedent to the Initial Extension of Credit	51
	Section 7.02	Conditions Precedent to all Extensions of Credit	53
	 	 	 
	ARTICLE VIII. EVENTS OF DEFAULT 	53
	Section 8.01	Events of Default	53
	Section 8.02	Lender’s Remedies Upon Default	56
	Section 8.03	Lender Protective Payments	57
	Section 8.04	Remedies Cumulative	57
	Section 8.05	Power of Attorney	57
	Section 8.06	Notice of Event of Default	58
	Section 8.07	Default under Other Encumbrances	58
	Section 8.08	Judgment	58
	Section 8.09	Application of Proceeds	58
	Section 8.10	Limitation of Liability	59
	Section 8.11	Borrower Liable	59
	 	 	 
	ARTICLE IX. GENERAL 	59
	Section 9.01	Releases	59
	Section 9.02	Governing Law; Jurisdiction; Jury Trial Waiver and Judicial  Reference	60
	Section 9.03	Whole Agreement	60
	Section 9.04	Time	60
	Section 9.05	Notices	60
	Section 9.06	Successors and Assigns	62
	Section 9.07	Indemnification	62
	Section 9.08	No Set-Off	63
	Section 9.09	Permitted Encumbrance	63

 

    - iii -

     

    

 

	Section 9.10	Press Releases	63
	Section 9.11	Confidentiality	63
	Section 9.12	Judgment Currency	63
	Section 9.13	Anti-Money Laundering Legislation	64
	Section 9.14	Counterparts	65

 

    - iv -

     

    

 

CREDIT AGREEMENT

 

This CREDIT AGREEMENT
(as amended, restated, supplemented or otherwise modified from time to time, the “Agreement”) dated as of July
30, 2018, by and among Profound Medical Inc., an Ontario corporation, as borrower (“Borrower”), Profound Medical
Corp., an Ontario corporation, as a guarantor (“Parent”), Profound Medical GmbH, a German limited liability
company (Gesellschaft mit beschränkter Haftung), as a guarantor (“PM Germany”) and Profound Medical
(U.S.) Inc., a Delaware corporation, as a guarantor (“PM USA”) and Canadian Imperial Bank of Commerce, as lender
(“Lender”).

 

WHEREAS the
Borrower has requested that Lender extend credit to it in a maximum aggregate principal amount of up to $18,750,000 for the various
purposes set out herein.

 

WHEREAS the
Borrower is a wholly-owned subsidiary of Parent and PM Germany and PM USA are each a wholly-owned subsidiary of the Borrower.

 

WHEREAS Parent,
PM Germany and PM USA have agreed to guarantee the obligations of the Borrower hereunder.

 

AND WHEREAS
Lender is willing to extend such credit on and subject to the terms and conditions hereof.

 

NOW THEREFORE
in consideration of the covenants and agreements herein the parties hereto agree as follows:

 

ARTICLE
I.

INTERPRETATION

 

Section 1.01         Definitions

 

In this Agreement:

 

“Account Debtor” means a person
obligated on an Account.

 

“Accounts” has the meaning given
to such term in the PPSA.

 

“Acquisition”
means, with respect to any Person, any purchase or other acquisition by such Person, regardless of how accomplished or effected
(including any such purchase or other acquisition effected by way of amalgamation, merger, arrangement, business combination or
other form of corporate reorganization or by way of purchase, lease or other acquisition arrangements), of (a) any other Person
(including any purchase or acquisition of such number of the issued and outstanding securities of, or such portion of an Equity
Interest in, such other Person so that such other Person becomes a Subsidiary of the purchaser or of any of its Affiliates) or
of all or a material portion of of the Property of any other Person, or (b) any division, business, operation or undertaking of
any other Person or of all or a material portion of the Property of any division, business, operation or undertaking of any other
Person or (c) any material real estate asset.

 

     

     

    

 

“Additional Documents” has the
meaning set forth in Section 4.05.

 

“Affiliate”
means, with respect to any Person, another Person that directly, or indirectly through one or more intermediaries, Controls or
is Controlled by or is under common Control with the Person specified.

 

“Agreement,”
 “hereto,” “herein,” “hereof,” “hereby,” “hereunder,”
and any similar expressions refer to this Agreement and the schedules attached hereto and not to any particular article, section
or other portion hereof, and include any and every instrument supplemental hereto or amending or replacing any part hereof.

 

“Applicable Law”
means, in respect of any Person, property, transaction, event or other matter, as applicable, all Laws relating or applicable to
such Person, property, transaction, event or matter.

 

“Board” means
a Person’s board of directors, board of managers, board of members or similar governing body, provided that, unless otherwise
specified, “Board” shall refer to the applicable Loan Party’s Board.

 

“Borrower”
has the meaning set forth in the preamble to this Agreement.

 

“Budget” means
the consolidated and consolidating projections and budget, prepared annually on a monthly basis, for Parent and its Subsidiaries
adopted and approved by Parent’s Board for the given period.

 

“Business Day”
means a day other than a Saturday, Sunday or any other day on which banks located in the City of Toronto, Province of Ontario are
not open for business.

 

“Canadian Dollars” and “$”
mean lawful money of Canada.

 

“Canadian Guarantee” has the meaning set forth in Section 4.01(b).

 

“Canadian IP Security Agreement”
has the meaning set forth in Section 4.01(e).

 

“Canadian Pension Plan”
means any “pension plan” that is subject to the funding requirements of the Pension Benefits Act (Ontario) or
applicable pension benefits legislation in any other Canadian jurisdiction.

 

“Canadian Security Agreement”
has the meaning set forth in Section 4.01(a).

 

“Capital Lease”
means any lease that would be considered to be a capital lease in accordance with GAAP; provided, that any lease that would be
considered to be an operating lease in accordance with GAAP on the date of this agreement shall not be considered to be a Capital
Lease notwithstanding any change in GAAP after such date that may reclassify it as a capital lease.

 

    	 	- 2 -	 

     

    

 

“Cash Equivalents”
means (a) marketable direct obligations issued or unconditionally guaranteed by the United States, the Government of Canada or
any agency or any State or Province, as applicable, thereof having maturities of not more than one (1) year from the date of acquisition;
(b) commercial paper maturing no more than one (1) year after its creation and having the highest rating from either Standard &
Poor’s Ratings Group or Moody’s Investors Service, Inc.; (c) certificates of deposit issued maturing no more than one
(1) year after issue; (d) money market funds at least ninety-five percent (95%) of the assets of which constitute Cash Equivalents
of the kinds described in clauses (a) through (c) of this definition; and (e) comparable instruments as those described
in clauses (a) through (d) for any Loan Party that is not formed under the federal or provincial laws of Canada and operates
in a jurisdiction outside of Canada.

 

“Casualty Event”
means, with respect to any Property of any Person, any loss of or damage to, or any condemnation or other taking of, such Property
for which such Person or any of its Subsidiaries receives insurance proceeds, or proceeds of a condemnation award or other compensation.

 

“CDOR” means,
on any date, the annual rate of interest which is the rate based on an average rate applicable to Canadian Dollar bankers’
acceptances for a specified term appearing on the “Reuters Screen CDOR Page” (as defined in the International Swaps
and Derivatives Association, Inc., definitions, as modified and amended from time to time) at approximately 10:00 a.m. (Toronto
time), on such date, or if such date is not a Business Day, then on the immediately preceding Business Day, provided that
if such rate does not appear on the Reuters Screen CDOR Page on such date as contemplated, then CDOR on such date shall be the
rate for the term referred to above applicable to Canadian Dollar bankers’ acceptances quoted by the Lender as of 10:00 a.m.
(Toronto time) on such date or, if such date is not a Business Day, then on the immediately preceding Business Day; provided
further, that if CDOR is less than zero, it shall be deemed to be zero hereunder.

 

“Centre of Main Interests”
means the “centre of main interests” of a Loan Party incorporated in a member state of the European Union as that term
is used in Article 3(1) of Regulation (EU) 2015/848 of the European Parliament and of the Council of 20 May 2015 on insolvency
proceedings (recast).

 

“Change of Control”
means, unless otherwise waived in writing by Lender, (a) the consummation of any transaction (including, without limitation, any
plan of arrangement, merger, amalgamation or consolidation) the result of which is that any Person or group of Persons acquires
or otherwise beneficially owns, directly or indirectly, or acquires or has the voting power and/or investment power in respect
of, 50% or more of the Shares of Parent; (b) the first day on which a majority of the members of the Board of the Parent are not
Continuing Directors; (c) if any Loan Party that is a Subsidiary of Parent ceases to be a wholly-owned Subsidiary of Parent or
any Subsidiary thereof, or any other Subsidiary ceases to be Controlled by Parent, other than as a result of an amalgamation with
a Loan Party or any other Subsidiary permitted hereunder; or (d) if there is an indirect event or transaction similar to the events
or transactions described above which has the same result or effect as the events or transactions described above whereby: (i)
with respect to any Loan Party other than the Parent, any Person or group of Persons other than an Existing Shareholder shall acquire
the right or ability to effectively Control any such Loan Party, and (ii) with respect to the Parent, any Person or group of Persons
shall acquire the right or ability to effectively Control the Parent. “Existing Shareholder” shall mean the
shareholders of each Loan Party as of the Closing Date set forth on Schedule 5.31.

 

    	 	- 3 -	 

     

    

 

“Change in Law”
means the occurrence, after the date of this Agreement, of any of the following: (a) the adoption or taking effect of any Law,
(b) any change in any Law or in the administration, interpretation, implementation or application thereof by any Governmental Authority
or (c) the making or issuance of any request, rule, guideline or directive (whether or not having the force of law, but in the
case of a request, rule, guideline or directive not having the force of law, being a request, rule, guideline or directive with
which Persons customarily, and are expected by the relevant Governmental Authority to, comply and nevertheless are considered to
be binding on such Person or its property) by any Governmental Authority; provided that notwithstanding anything herein
to the contrary, (i) the Dodd-Frank Wall Street Reform and Consumer Protection Act and all requests, rules, guidelines or directives
thereunder or issued in connection therewith and (ii) all requests, rules, guidelines or directives promulgated by the Bank for
International Settlements, the Basel Committee on Banking Supervision (or any successor or similar authority) or the United States,
European or foreign regulatory authorities, in each case pursuant to Basel III, shall in each case be deemed to be a “Change
in Law”, regardless of the date enacted, adopted or issued.

 

“Closing Date” means the date of
this Agreement.

 

“Closing Fee” has the meaning set forth in Section 2.03(b).

 

“Collateral”
means all assets, property (both real and personal) and undertaking that is subject to grant of security pursuant to a Security
Document.

 

“Collateral Access Agreement”
means an agreement, in form and substance reasonably satisfactory to Lender, executed and delivered by a Loan Party and the landlord
with respect to any applicable leased facility, which agreement is sufficient to give Lender access to any Collateral located at
such leased facility.

 

“Commitment Fee”
has the meaning set forth in Section 2.03(a).

 

“Compliance Certificate” means
a certificate in the form of Exhibit B hereto.

 

“Continuing Directors”
means, as of any date of determination, any member of the Board of any Loan Party or any of their respective Subsidiaries (1) who
was a member of such Board on the Closing Date or (2) whose election or nomination for election to such Board has been approved
by a majority of the Continuing Directors who were at the time of such nomination or election members of such Board.

 

“Control”
means the possession, directly or indirectly, of the power to direct or cause the direction of the management or policies of a
Person, whether through the ability to exercise voting power by contract or otherwise; “Controlling”, “Controlled”
and “Controls” have meanings correlative thereto.

 

    	 	- 4 -	 

     

    

 

“Control Agreement”
means an agreement, in form and substance reasonably satisfactory to Lender, executed and delivered by a Loan Party and the applicable
securities intermediary or bank, which agreement is sufficient to give Lender “control” over the subject Securities
Account, Deposit Account or Investment Property under the PPSA or applicable foreign Law, as applicable, and in the case of a Deposit
Account governed by Canadian laws, shall include a blocked account agreement the effect of which would be similar to a control
agreement even though it may not be required for “control” under Law.

 

“Default”
means any event specified in Section 8.01 hereof, whether or not any requirement in connection with such event for the giving
of notice, lapse of time or happening of any further condition has been satisfied.

 

“Deposit Account”
means any checking account, demand deposit account or other deposit or bank account maintained by a Loan Party.

 

“Disposition”
means any sale, assignment, transfer or other disposition of any Property (whether now owned or hereafter acquired) by a Loan Party
or any of its Subsidiaries to any other Person excluding any sale, assignment, transfer or other disposition of any Property sold
or disposed of in the ordinary course of business and on ordinary business terms.

 

“End of Term Payment”
has the meaning set forth in Section 3.03.

 

“Environmental Laws”
means any and all present and future federal, provincial, state, local and foreign laws, rules or regulations, and any orders or
decrees, in each case as now or hereafter in effect, relating to the regulation or protection of human health, safety or the environment
or to emissions, discharges, releases or threatened releases of pollutants, contaminants, chemicals or toxic or hazardous substances
or wastes into the indoor or outdoor environment, including, without limitation, ambient air, soil, surface water, ground water,
wetlands, land or subsurface strata, or otherwise relating to the manufacture, processing, distribution, use, treatment, storage,
disposal, transport or handling of pollutants, contaminants, chemicals or toxic or hazardous substances or wastes.

 

“Equipment”
has the meaning given to such term in the PPSA.

 

“Equity Interests”
means (a) in the case of any corporation or company, all shares or capital stock and any securities exchangeable for or convertible
into shares or capital stock, (b) in the case of an association or business entity, any and all shares, interests, participation
rights or other equivalents of corporate stock (however designated) in or to such association or entity, (c) in the case of a partnership,
limited liability company or unlimited liability company, partnership or membership interests (whether general or limited), as
applicable, and (d) any other interest or participation that confers on a Person the right to receive a share of the profits and
losses of, or distribution of assets of, the issuing Person, and including, in all of the foregoing cases described in clauses
(a), (b), (c) or (d), any warrants, rights or other options to purchase or otherwise acquire any of the interests described
in any of the foregoing cases.

 

    	 	- 5 -	 

     

    

 

“Establishment”
has the meaning as used in Article 2(10) of Regulation (EU) 2015/848 of the European Parliament and of the Council of 20 May 2015
on insolvency proceedings (recast).

 

“Event of Default”
has the meaning set forth in Section 8.01.

 

“Exchange Rate”
means, in relation to the conversion of one currency into another currency, the spot rate of exchange quoted for by the Lender
in accordance with its usual practice at 11:00am Toronto time on the Business Day such conversion is to be made in accordance with
its normal practice.

 

“Excluded Accounts”
means collectively (a) non-collection Deposit Accounts that collectively hold an aggregate of no more than $500,000, (b) for the
period beginning on the Closing Date and terminating 90 days thereafter, Deposit Accounts that are located in Canada and collectively
hold an aggregate of no more than $2,000,000 and (c) Deposit Accounts that are located in Canada and maintained with the Lender
or an Affiliate of the Lender.

 

“Excluded Taxes”
means, any of the following Taxes imposed on or with respect to the Lender or required to be withheld or deducted from a payment
to the Lender, (a) Taxes imposed on or measured by net income (however denominated), franchise or capital Taxes, and branch profits
Taxes, in each case, imposed as a result of the Lender being organized under the laws of, or having its principal office or its
applicable lending office located in, the jurisdiction imposing such Tax (or any political subdivision thereof), (b) withholding
Taxes of the United States imposed on amounts payable to or for the account of the Lender with respect to an applicable interest
in a Loan pursuant to a Law in effect on the date on which (i) the Lender acquires by assignment such interest in a Loan or (ii)
the Lender changes its lending office, except in each case to the extent that, pursuant to Section 3.10(c), amounts with
respect to such Taxes were payable either to the Lender’s assignor immediately before the Lender became a party hereto or
to the Lender immediately before it changed its lending office, and (c) Taxes imposed under FATCA.

 

“Existing Loan Facility”
means the loan by Knight Therapeutics Inc. in favour of Borrower established pursuant to the loan agreement dated as of April 30,
2015 among Knight Therapeutics Inc. and Borrower.

 

“FATCA” means
sections 1471 through 1474 of the Internal Revenue Code (U.S.), as of the date of this Agreement (or any amended or successor version
that is substantively comparable and not materially more onerous to comply with), any current or future regulations or official
interpretations thereof, any intergovernmental agreement or foreign legislation (including official administrative rules or practices)
implemented to give effect to any intergovernmental agreements entered into thereunder and any agreements entered into pursuant
to section 1471(b) of the Internal Revenue Code (U.S.).

 

    	 	- 6 -	 

     

    

 

“Financing Documents”
means this Agreement, the Canadian Guarantee, any other Guarantee, the Security Documents, all Additional Documents and any other
document, instrument or agreement now or hereafter entered into in connection with the Secured Obligations or the Collateral.

 

“GAAP” means
generally accepted accounting principles which are in effect from time to time in Canada, and which on the Closing Date encompass
International Financial Reporting Standards adopted by the Canadian Accounting Standards Board provided that if the Loan Parties
convert its consolidated financial reporting to US GAAP, in accordance with Section 1.08, then GAAP shall mean US GAAP.

 

“German Security Agreements”
has the meaning set forth in Section 4.01(e).

 

“Governing Documents”
means, for any Person, such Person’s formation documents, as certified by the applicable governmental agency of such Person’s
jurisdiction of organization (provided that in case of any later updates to such certified documents a print-out from the electronic
commercial register will be sufficient), and, (a) if such Person is a corporation, its certificate of incorporation or formation
and bylaws, (b) if such Person is a limited liability company, its certificate of incorporation and/or limited liability company
agreement (or similar agreement), and (c) if such Person is a partnership or limited partnership, its partnership agreement (or
similar agreement), in each case, including all amendments or modifications thereto.

 

“Governmental Authority”
means any nation or government, any provincial, state or other political subdivision thereof, any agency, authority, instrumentality,
regulatory body, court, central bank or other entity exercising executive, legislative, judicial, taxing, regulatory or administrative
functions of or pertaining to government, any securities exchange and any self-regulatory organization.

 

“Guarantee”
means any guarantee of the Secured Obligations entered into on or after the Closing Date by any Person required to provide a Guarantee
in accordance with the terms of this Agreement (including, without limitation, pursuant to Section 4.01  and Section
4.03 hereof) and which for greater certainty shall include the Canadian Guarantee, which shall be in form and substance satisfactory
to the Lender.

 

“Guarantor”
means, collectively, (i) Parent, PM Germany and PM USA, and (ii) any person providing a Guarantee in favor of Lender under the
terms of Section 4.03.

 

“Hazardous Materials” has the meaning
set forth in Section 5.13.

 

“Healthcare Laws”
means, collectively, any and all federal, state, provincial or local laws, rules, regulations and administrative manuals, orders,
guidelines and requirements issued under or in connection with any government payment program or any law governing the establishment,
certification, licensure of or regulating healthcare providers, professionals, facilities (including nursing facilities), medical
devices, medications or payors or otherwise governing or regulating the provision of, or payment for, medical and healthcare services.

 

    	 	- 7 -	 

     

    

 

“Hedge Arrangement”
means, for any period, for any Person, any arrangement or transaction between such Person and any other Person which is an interest
rate swap transaction, basis swap, forward interest rate transaction, commodity swap, interest rate option, forward foreign exchange
transaction, cap transaction, floor transaction, collar transaction, currency swap transaction, cross-currency interest rate swap
transaction, currency option or any other similar transaction (including any option with respect to any of such transactions or
arrangements) designed to protect or mitigate against risks in interest, currency exchange or commodity price fluctuations.

 

“Indebtedness”
of a Loan Party or any of its Subsidiaries, as the case may be, means, without duplication:

 

		(a)	all of its indebtedness for or in respect of borrowed
money, credit or other financial accommodation, including liabilities and obligations with respect to letters of credit, letters
of guarantee, bankers’ acceptances or similar instruments issued or accepted by banks and other financial institutions for
the account of such Loan Party or any of its Subsidiaries and all obligations evidenced by notes, bonds, debentures or other similar
instruments;

 

		(b)	all obligations for or in respect of the deferred purchase
or acquisition price of Property or services, whether or not recourse is limited to the repossession and sale of any such Property;

 

		(c)	all obligations under any lease entered into as lessee
which would be classified as a capital lease in accordance with GAAP;

 

		(d)	all obligations of it to purchase, redeem, retract or
otherwise acquire any securities issued by such Loan Party or any of its Subsidiaries where such obligation has been exercised
or otherwise become payable;

 

		(e)	all obligations under Hedge Arrangements; and

 

		(f)	all guarantees by such Loan Party or any of its Subsidiaries
or any of its Subsidiaries of any of the foregoing, or obligations of such Loan Party or any of its Subsidiaries to purchase or
acquire any of the foregoing, or any other assurance given by such Loan Party or any of its Subsidiaries to a creditor of another
Person against loss in connection with any of the foregoing incurred by such other Person;

 

but “Indebtedness”
shall not include unsecured trade debt incurred in the ordinary course of business, issued share capital or surplus, reserves (including,
for certainty, reserves in connection with purchase orders) for deferred taxes or general contingencies, minority interests in
Subsidiaries, operating leases, nor any contingent liabilities in connection with contracts entered into in the ordinary course
of business.

 

“Indemnified Claim”
has the meaning set forth in Section 9.05.

 

“Indemnified Person” has the meaning
set forth in Section 9.07.

 

    	 	- 8 -	 

     

    

 

“Indemnified Taxes”
means Taxes, other than Excluded Taxes imposed on or with respect to any payment made by or on account of any obligation of Borrower.

 

“Insolvency Legislation”
means legislation in any applicable jurisdiction relating to reorganization, arrangement, compromise or re-adjustment of debt,
dissolution or winding-up, or any similar legislation, and specifically includes for greater certainty the BIA, the Companies’
Creditors Arrangement Act (Canada), the German Insolvency Code (Insolvenzordnung) (Germany), the Winding-Up and Restructuring
Act (Canada) and the Bankruptcy Code (United States), together with any other similar statutes (including corporate
statutes) in Canada or any other applicable jurisdiction in which any Loan Party operates.

 

“Insolvency Proceeding”
is any proceeding by or against any Person under any Insolvency Legislation, or any other bankruptcy or insolvency law, including
assignments for the benefit of creditors, compositions, extensions generally with its creditors, or proceedings seeking reorganization,
arrangement, or other relief.

 

“Instruments”
has the meaning given to such term in the PPSA.

 

“Intellectual Property”
means the following properties and assets owned or held or in which the applicable Person otherwise has any interest, now existing
or hereafter acquired or arising:

 

		(a)	all patents and patent applications, domestic or foreign,
all licenses relating to any of the foregoing and all income and royalties with respect to any licenses, all rights to sue for
past, present or future infringement thereof, all rights arising therefrom and pertaining thereto and all reissues, divisions,
continuations, renewals, extensions and continuations-in-part thereof;

 

		(b)	all copyrights and applications for copyright, domestic
or foreign, together with the underlying works of authorship (including titles), whether or not the underlying works of authorship
have been published and whether said copyrights are statutory or arise under the common law, and all other rights and works of
authorship, all computer programs, computer databases, computer program flow diagrams, source codes, object codes and all tangible
Property embodying or incorporating any copyrights, all licenses relating to any of the foregoing and all income and royalties
with respect to any licenses, and all other rights, claims and demands in any way relating to any such copyrights or works, including
royalties and rights to sue for past, present or future infringement, and all rights of renewal and extension of copyright;

 

		(c)	all state and provincial (including common law), federal
and foreign trade-marks, service marks and trade names, and applications for registration of such trademarks, service marks and
tradenames, all licenses relating to any of the foregoing and all income and royalties with respect to any licenses, whether registered
or unregistered and wherever registered, all rights to sue for past, present or future infringement or unconsented use thereof,
all rights arising therefrom and pertaining thereto and all reissues, extensions and renewals thereof;

 

    	 	- 9 -	 

     

    

 

		(d)	all technology created, developed or acquired by such
Person, trade secrets, trade dress, trade styles, logos, other sources of business identifiers, mask-works, mask-work registrations,
mask-work applications, software, proprietary or confidential information, customer lists, license rights, advertising materials,
operating manuals, methods, processes, know-how, techniques, research, studies, algorithms, formulae, databases, quality control
procedures, product, service and technical specifications and data, operating, production and quality control manuals, sales literature,
drawings, specifications, blue prints, descriptions, inventions, name plates and catalogs;

 

		(e)	all domain names, internet protocol addresses and uniform
resource locators used in the business and all applications, registrations and rights therein and thereto;

 

		(f)	the entire goodwill of or associated with the businesses
now or hereafter conducted connected with and symbolized by any of the aforementioned properties and assets; and

 

		(g)	all accounts, all intangible intellectual or other similar
Property and other general intangibles associated with or arising out of any of the aforementioned properties and assets and not
otherwise described above.

 

“Intellectual Property
Security Agreements” means (i) the Canadian IP Security Agreement, the (ii) US IP Security Agreement, and (iii) any other
security agreement covering the Intellectual Property of the Loan Parties, in each case as amended, restated, supplemented or otherwise
modified from time to time.

 

“Investment” means any direct or
indirect:

 

		(a)	purchase or other acquisition of Equity Interest or other
securities of any other Person or any beneficial interest therein;

 

		(b)	purchase or other acquisition of bonds, notes, debentures
or other debt securities of any other Person or beneficial interest therein;

 

		(c)	loan or advance to any other Person; and

 

		(d)	capital contribution to any other Person.

 

“Investment Property” has the meaning
given to such term in the PPSA.

 

“ITA” means the Income Tax Act
(Canada), as amended from time to time.

 

“Law” means any statute, law, ordinance,
regulation, rule, order, writ, injunction, policies, practices, directives, guidelines or decree of any Tribunal, and which for
greater certainty shall include Healthcare Laws and any policies, practices, directives or guidelines of the TSX.

 

    	 	- 10 -	 

     

    

 

“Lender” has
the meaning set forth in the preamble to this Agreement.

 

“Lender Expenses”
means all reasonable fees, costs, expenses (including, without limitation, reasonable attorneys’ and other legal fees, costs
and expenses and audit fees), or any other reasonable charges incurred by Lender in the negotiation, preparation, amendment, administration,
monitoring, defense, enforcement and restructuring of the Financing Documents (including without limitation, those incurred after
appeal or in Insolvency Proceedings) or the exercise of remedies pursuant thereto, or otherwise incurred by Lender with respect
to any Loan Party or the Financing Documents.

 

“Lien” means
any lien, mortgage, charge, hypothecation, pledge, security interest, prior assignment, option, warrant, lease, sublease, right
to possession, right of distress, encumbrance, claim, right or restriction which affects, by way of a conflicting ownership interest
or otherwise, the right, title or interest in or to any particular property. For purposes of the Financing Documents, a Person
shall be deemed to own subject to a Lien any property that it has acquired or holds subject to the interest of a vendor or lessor
under any conditional sale agreement, capital lease or other title retention agreement relating to such property.

 

“Loan Account”
has the meaning set forth in Section 2.05.

 

“Loan Parties”
means Borrower, Parent and each Guarantor from time to time party hereto or any other Financing Document, collectively, and “Loan
Party” means any one of such parties.

 

“Loans” means
the Term Loans and any other amounts owing to Lender by Borrower under the Financing Documents.

 

“Material Adverse Change”
means a material adverse change in the business, assets, operations, prospects or condition, financial or otherwise, of the Borrower
or any other Loan Party.

 

“Material Adverse Effect”
means a material adverse effect on (a) the business, assets, liabilities (actual or contingent), financial condition, operations,
performance or properties of the Loan Parties and their Subsidiaries taken as a whole, (b) the ability of the Loan Parties to perform
their obligations under the Financing Documents, (c) the validity or enforceability of the Financing Documents or the Lien granted
to Lender thereunder, or (d) the rights and remedies of Lender under the Financing Documents.

 

“Material Agreements”
any contract, agreement, license, sublicense, supply agreement, permit, lease or other instrument, the termination of which would
reasonably be expected to have a Material Adverse Effect, including, without limitation, the agreements set forth on Schedule
5.09.

 

    	 	- 11 -	 

     

    

 

“Material Intellectual
Property” means all Intellectual Property and license or sublicense agreements or other agreements with respect to rights
in Intellectual Property, of any Loan Party or any of its Subsidiaries, that is material to the business or operations of the Loan
Parties on a consolidated basis.

 

“Material Subsidiary”
means (i) each present and future Subsidiary of Parent that at any time individually accounts for more than 7.5% of either the
revenue or assets of Parent on a consolidated basis, (ii) each present and future Subsidiary of Parent that at any time, when aggregated
with all other Subsidiaries that are not Loan Parties, accounts for more than 15% of either the revenue or assets of Parent on
a consolidated basis and (iii) each other present and future Subsidiary of Parent that is a party to a Material Agreement or holds
any Intellectual Property that is material to Parent’s or Borrower’s business.

 

“Maturity Date”
means July 29, 2022.

 

“Monthly Interest Amount”
has the meaning set forth in the defined term “Term Loan Interest Rate”.

 

“Net Available Proceeds”
means:

 

		(a)	in the case of any Disposition, the amount of Net Cash
Payments received in connection with such Disposition; and

 

		(b)	in the case of any Casualty Event, the aggregate amount
of proceeds of insurance, condemnation awards and other compensation received by a Loan Party or any of its Subsidiaries in respect
of such Casualty Event net of (A) reasonable expenses incurred by a Loan Party or any of its Subsidiaries in connection therewith
and (B) contractually required repayments of Indebtedness to the extent secured by a Lien on such property and any income and
transfer taxes payable by a Loan Party or any of its Subsidiaries in respect of such Casualty Event.

 

“Net Cash Payments”
means, with respect to any Disposition, the aggregate amount of all cash payments, and the fair market value of any non-cash consideration,
received by a Loan Party or any of its Subsidiaries directly or indirectly in connection with such Disposition; provided that Net
Cash Payments shall be net of (i) the amount of any legal, title and recording tax expenses, commissions and other fees and expenses
paid by a Loan Party or any of its Subsidiaries in connection with such Disposition and (ii) any federal, provincial, state and
local income or other taxes estimated to be payable by a Loan Party or any of its Subsidiaries as a result of such Disposition.

 

“Non-Canadian Pension
Plan” means any “pension plan”, scheme, fund (including any superannuation fund) or other similar program
established, sponsored or maintained outside of Canada by any Loan Party primarily for the benefit of employees of such Loan Party
residing outside Canada, which is subject to statutory funding requirements in advance of the payment of pension benefits thereunder,
and which plan is not subject to the funding requirements of the Pension Benefits Act (Ontario) or applicable pension benefits
legislation in any other Canadian jurisdiction. For clarity Non-Canadian Pension Plan shall include, without limitation, any such
plan maintained in Germany.

 

    	 	- 12 -	 

     

    

 

“Operating Cash Expenditures”
means the aggregate of all operating expenses of the Loan Parties on a consolidated basis, including, without limitation, all expenditures
associated with the maintenance, administration and operation of the Loan Parties.

 

“Parent” has
the meaning set forth in the preamble to this Agreement.

 

“Pension Plan”
means a Canadian Pension Plan or a Non-Canadian Pension Plan.

 

“Pension Plan Event”
means, to the extent a Loan Party or a Subsidiary forms or acquires a Pension Plan after the Closing Date, (i) the institution
of any steps by any Loan Party or any applicable regulatory authority to terminate a Pension Plan if, as a result of such termination,
any such Loan Party shall be required to make an additional contribution to such Pension Plan or to incur an additional liability
or obligation to such Pension Plan equal to or in excess of $250,000; or (ii) the taking of any steps to establish, fund or otherwise
contribute to a Canadian Pension Plan that contains a “defined benefit provision” as such term is defined under the
ITA.

 

“Permit” has
the meaning set forth in Section 5.19.

 

“Permitted Acquisition” means any
Acquisition that complies with the following criteria:

 

		(a)	no Event of Default exists at the time of such Acquisition
or would exist after giving effect to such Acquisition;

 

		(b)	the Acquisition is non-hostile in nature;

 

		(c)	the person, division, product line of business acquired
in such Acquisition shall be in the same or substantially similar line of business as Borrower or in an adjacent line of business;

 

		(d)	the total aggregate consideration for the Acquisition,
together with all other Acquisitions hereunder, is not greater than $10,000,000;

 

		(e)	if the Acquisition is of a Material Subsidiary, it shall
provide a Guarantee and deliver such Security Documents and certificates as are consistent with the documentation provided to
the Lender by a Loan Party and comply with the requirements of Section 4.01 and Section 4.03, and if it is an Acquisition
of assets it shall otherwise comply with Article IV; and

 

		(f)	the Loan Parties (i) demonstrate pro forma compliance
with the financial covenant set out in Section 6.19 for the trailing three month period ending immediately prior to the
date of the proposed Acquisition before giving effect to such Acquisition and, (ii) reasonably project that the Loan Parties will
remain in compliance for the following two (2) fiscal quarters with such financial covenant after giving effect to such Acquisition.

 

    	 	- 13 -	 

     

    

 

“Permitted Distribution” means
any of the following:

 

		(a)	the conversion of any convertible securities into other
securities pursuant to the terms of such convertible securities as long as the conversion does not involve any payment of cash;

 

		(b)	the payment of dividends solely in equity securities
a Loan Party;

 

		(c)	the payment of dividends or other distributions in cash
from any Loan Party to any other Loan Party;

 

		(d)	payment of dividends by the Parent pursuant to the then
most recent Budget in an amount up to 115% of the amount set forth in such Budget provided that no Event of Default exists and
is continuing;

 

		(e)	the repurchase of stock, with the exception of preferred
stock, of former employees, independent directors or consultants pursuant to stock repurchase agreements up to an aggregate of
$250,000 per fiscal year or in connection with a normal course issuer bid.

 

“Permitted Encumbrances” means
any of the following:

 

		(a)	Liens set forth on Schedule 1.01 hereto existing
as of the Closing Date;

 

		(b)	Liens for Taxes not at the time due unless contested
in good faith by all necessary proceedings and reserves satisfactory to Lender acting reasonably have been taken;

 

		(c)	rights reserved to or vested in any municipality or governmental
or other public authority by the terms of any lease, license, franchise, grant or permit, or by any statutory provision, to terminate
the same or to require annual or other periodic payments as a condition to the continuance thereof;

 

		(d)	reservations, limitations, provisos and conditions expressed
in any original grants from the Crown or other grants of real or immovable property, or interests therein, which do not materially
affect the use of the affected land for the purpose for which it is used by that Person, and title defects, encroachments or irregularities
or other matters relating to title which are of a minor nature and which in the aggregate do not materially impair the use of
the affected property for the purpose for which it is used by that Person;

 

		(e)	a security interest in cash or governmental obligations
deposited in the ordinary course of business to secure worker’s compensation, unemployment insurance, public and statutory
obligations, mechanics’, warehousemen’s, carriers’ and other similar liens arising by operation of law in the
ordinary course of business and which are not registered or enforceable against any property of any Loan Party;

 

    	 	- 14 -	 

     

    

 

		(f)	Lien created by a judgment of a court of competent jurisdiction,
as long as the judgment is being contested diligently and in good faith by appropriate proceedings or is promptly satisfied by
that Person and does not result in an Event of Default;

 

		(g)	Liens on Equipment securing the unpaid purchase price
thereof and/or Liens securing Capital Leases; provided that the Indebtedness secured thereby (plus any Indebtedness for equipment
financings and Capital Leases as may be set forth on Schedule 1.01 hereto) does not exceed $500,000 and such security interest
is limited to the Equipment so leased or acquired;

 

		(h)	Liens granted to Lender to secure the Secured Obligations;

 

		(i)	inchoate liens or any rights of distress reserved in
or exercisable under any real property lease or sublease to which any Loan Party is a lessee which secure the payment of rent
or compliance with the terms of such lease or sublease, provided that such rent is not then overdue and such Loan Party is then
in compliance in all material respects with such terms;

 

		(j)	any Lien which does not secure Indebtedness, the satisfaction
of which has been provided for by deposit with the Lender of cash or a surety bond or other security satisfactory to the Lender
in an amount sufficient to pay the liability in respect of such Lien in full; and

 

		(k)	any other encumbrances Lender declares in writing to
be Permitted Encumbrance.

 

“Permitted Indebtedness”
means any of the following:

 

		(a)	Indebtedness set forth on Schedule 1.01, existing
as of the Closing Date;

 

		(b)	the Secured Obligations;

 

		(c)	Indebtedness in connection with Capital Leases in an
amount not to exceed $500,000; and

 

		(d)	unsecured Indebtedness not otherwise permitted in an
aggregate amount not to exceed $500,000 outstanding in the aggregate at any given time.

 

“Permitted Investments” means:

 

		(a)	Investments set forth on the Schedule 1.01, existing
as of the Closing Date;

 

		(b)	Investments consisting of Cash Equivalents;

 

		(c)	Investments in a Loan Party or any Subsidiary, provided
that Investments of the Loan Parties in a Subsidiary that is not a Loan Party shall not exceed $500,000 per fiscal year;

 

    	 	- 15 -	 

     

    

 

		(d)	Investments consisting of (a) travel advances and employee
relocation loans and other employee loans and advances in the ordinary course of business, and (a) loans to employees, officers
or directors relating to the purchase of equity securities of any Loan Party pursuant to employee stock purchase plans or agreements
approved by such Loan Party’s Board, up to a maximum of $500,000 per annum; and

 

		(e)	Investments consisting of Securities Accounts (and the
Investment Property therein) in which Lender has a Control Agreement covering such Securities Account.

 

“Person” is
to be interpreted broadly and includes any individual, partnership, limited partnership, joint venture, syndicate, sole proprietorship,
company, limited liability company or corporation with or without share capital, unincorporated association, trust, trustee, executor,
administrator or other legal personal representative, regulatory body or agency, government or governmental agency, authority or
entity however designated or constituted.

 

“Plan” means an employee benefit
or other plan established or maintained by a Loan Party.

 

“PM Germany” has the meaning set
forth in the preamble to this Agreement.

 

“PM USA” has the meaning set forth
in the preamble to this Agreement.

 

“Post-Default Rate” has the meaning
set forth in Section 3.02(b).

 

“PPSA” means
the Personal Property Security Act (Ontario) as in effect from time to time and the regulations and orders made thereunder,
or, in respect of Collateral located in a Canadian province other than Ontario, the personal property security act, regulations
and orders in effect in such other province from time to time.

 

“Prime Rate”
means a fluctuating rate of interest per annum, expressed on the basis of a year of 365 or 366 days, as applicable, which is equal
at all times to the greater of (i) the base rate of interest (however designated) of the Lender for determining interest chargeable
by it on Canadian Dollar commercial loans made in Canada; and (ii) 1.00% above CDOR from time to time for one month Canadian Dollar
bankers’ acceptances having a face amount comparable to the face amount in respect of which the applicable Prime Rate calculation
is being made. Any change in the Prime Rate due to a change in the applicable base rate or CDOR from time to time shall be effective
from and including the effective date of such change.

 

“Proceedings”
has the meaning set forth in Section 5.21.

 

“Product”
means each product, process or service under development, developed, manufactured, licensed, distributed, marketed or sold by any
Loan Party and any other similar products or services in which any Loan Party has any proprietary rights or beneficial interests,
which for greater certainty shall include the TULSA-PRO and Sonalleve.

 

    	 	- 16 -	 

     

    

 

“Property”
means any interest in any kind of property or asset, whether real, personal or mixed, or tangible or intangible.

 

“Regulatory Authority”
means any Governmental Authority that has responsibility in any country or group of countries over the development, manufacture
or commercialization of a Product, including the U.S. Food and Drug Administration, Health Canada and the European Medicines Agency,
and any successor agency thereof.

 

“Regulatory Reporting
Event” has the meaning set forth in Section 6.12.

 

“Regulatory Required
Permit” means any and all licenses, approvals and permits issues by any Regulatory Authority or any other Governmental
Authority necessary for the testing, manufacture, marketing or sale of any Product by any Loan Party and their respective Subsidiaries.

 

“Responsible Officer”
means a Loan Party’s chief executive officer or chief financial officer. Any document delivered hereunder that is signed
by a Responsible Officer shall be conclusively presumed to have been authorized by all necessary corporate or other action on the
part of such Loan Party and such Responsible Officer shall be conclusively presumed to have acted on behalf of such Loan Party.

 

“Secured Obligations”
means all advances to, and debts, liabilities, obligations, covenants and duties of each Loan Party arising under this Agreement
or any other Financing Document or otherwise with respect to any Loan, including, without limitation, Lender Expenses, whether
direct or indirect (including those acquired by assumption), absolute or contingent, due or to become due, now existing or hereafter
arising and including interest and fees that accrue after the commencement by or against any Loan Party of any Insolvency Proceeding.

 

“Securities Account”
has the meaning given to such term in the PPSA.

 

“Security Agreements”
means the Canadian Security Agreement, the German Security Agreements and the USA Security Agreement.

 

“Security Documents”
means each Security Agreement, any Collateral Access Agreements, any Control Agreement, the Intellectual Property Security Agreements,
all PPSA and applicable foreign Law financing statements required thereby to be filed with respect to the security interests in
personal Property and fixtures created pursuant thereto, and any and all other agreements or instruments now or hereafter executed
and delivered to Lender by any Loan Party or any other Person as security for the Secured Obligations.

 

“Shares” means
the issued and outstanding capital stock, membership units or other securities owned or held of record at any time by any Loan
Party in any Subsidiary of such Loan Party.

 

    	 	- 17 -	 

     

    

 

“Sonalleve”
means the innovative therapeutic platform combining real time MR imaging and thermometry with thermal ultrasound to enable precise
and incision-free ablation of diseased tissue, CE marked for the treatment of uterine fibroids and palliative pain treatment of
bone metastases.

 

“Subsidiary”
means, with respect to any Person, any corporation, limited corporation, limited liability company, partnership, limited partnership
or other entity of which at least a majority of the securities or other ownership interests having by the terms thereof ordinary
voting power to elect a majority of the board of directors or other persons performing similar functions of such corporation, limited
corporation, limited liability company, partnership, limited partnership or other entity (irrespective of whether or not at the
time securities or other ownership interests of any other class or classes of such corporation, limited corporation, limited liability
company, partnership, limited partnership or other entity shall have or might have voting power by reason of the happening of any
contingency) is at the time directly or indirectly owned or Controlled by such Person or one or more Subsidiaries of such Person
or by such Person and one or more Subsidiaries of such Person. Unless otherwise specified herein, “Subsidiary” means
a direct or indirect Subsidiary of a Loan Party.

 

“Taxes” or
 “Tax” means all present and future taxes, charges, fees, levies, imposts, surtaxes, duties and other assessments,
including all income, sales, use, goods and services, value added, capital, capital gains, alternative, net worth, transfer, profits,
withholding, payroll, employer health, excise, real property and personal property taxes, and any other taxes, customs duties,
fees, assessments, or similar charges of any nature, including Canada Pension Plan or similar plan in any other jurisdiction, and
provincial pension plan contributions, unemployment insurance payments and workers’ compensation premiums and including all
present or future stamp or documentary taxes or any other excise or property taxes, charges or similar levies arising from any
payment made hereunder or under any other Financing Document or from the execution, delivery of enforcement of, or otherwise with
respect to, any Financing Document, together with any instalments with respect thereto, and any interest, fines and penalties with
respect thereto, imposed by any Governmental Authority (including federal, state, provincial, municipal and foreign Governmental
Authorities), and whether disputed or not.

 

“Term Loan”
has the meaning set forth in Section 2.01(a).

 

“Term Loan Interest
Rate” means for each of the Tranche A Term Loan and the Tranche B Term Loan, a rate equal to the Prime Rate plus 2.5%
per annum, which shall be payable monthly in cash in arrears (the “Monthly Interest Amount”).

 

“Term Sheet”
means the term debt financing term sheet issued on May 25, 2018 by Lender and accepted on May 28, 2018 by Borrower.

 

“Tranche A Closing Fee”
has the meaning set forth in Section 2.03(b).

 

“Tranche A Commitment Fee” has
the meaning set forth in Section 2.03(a).

 

“Tranche A Term Loan” has the meaning
set forth in Section 2.01(a).

 

    	 	- 18 -	 

     

    

 

“Tranche B Availability Period”
means the period commencing on the Closing Date and ending on December 31, 2019.

 

“Tranche B Closing Fee” has the
meaning set forth in Section 2.03(b).

 

“Tranche B Commitment Fee” has
the meaning set forth in Section 2.03(a).

 

“Tranche B Conditions” means:

 

		(a)	no Default or Event of Default has occurred and is continuing
since the Closing Date or will occur as a result of a drawdown under the Tranche B Term Loan;

 

		(b)	the company has raised not less than $20,000,000 in new
equity since the Closing Date and has provided satisfactory evidence of same to the Lender; and

 

		(c)	TULSA-PRO has received approval from the U.S. Food and
Drug Administration under Section 510(k) of the Food, Drug and Cosmetic Act (United States).

 

“Tranche B Initial Drawdown” means
the first advance of the Tranche B Term Loan after the Closing Date.

 

“Tranche B Term Loan” has the meaning
set forth in Section 2.01(a).

 

“Tranche B Term Loan Request” is
a request pursuant to Section 2.02(b) in the form of Exhibit A attached hereto.

 

“Tribunal”
means any state, commonwealth, federal, foreign, territorial or other court or government body, subdivision, agency, department,
commission, board, bureau or instrumentality of a governmental body.

 

“TSX” means
the Toronto Stock Exchange.

 

“TULSA-PRO”
is a therapy that combines real-time Magnetic Resonance Imaging with transurethral, robotically-driven therapeutic ultrasound and
closed-loop thermal feedback control to provide precise ablation of the prostate while simultaneously actively protecting critical
surrounding anatomy from potential side effects.

 

“Unrestricted Cash”
means cash and Cash Equivalents of Borrower that do not appear on Borrower’s balance sheet as “restricted cash”
and that (i) are deposited in Canada, Germany or the United States of America in a Deposit Account with the Lender or with an Affiliate
of the Lender or (ii) otherwise deposited in Deposit Accounts or Securities Accounts subject to a Control Agreement.

 

“US GAAP”
means generally accepted accounting principles that are in effect from time to time in the United States of America.

 

“US IP Security Agreement”
has the meaning set forth in Section 4.01(h).

 

    	 	- 19 -	 

     

    

 

“Warrants” means the warrants granted
by the Parent in favour of Lender the from time to time exercisable for one common share in the capital of the Parent.

 

“Welfare Plan”
means any medical, health, hospitalization, insurance or other employee benefit or welfare plan or arrangement applicable to employees
resident in Canada, Germany or any other jurisdiction in which any Loan Party operates.

 

Section 1.02         PPSA.

 

Any terms used in this
Agreement that are defined in the PPSA shall be construed and defined as set forth from time to time in the PPSA unless otherwise
defined herein.

 

Section 1.03         Headings.

 

The inclusion of headings
in this Agreement is for convenience of reference only and shall not affect the construction or interpretation hereof.

 

Section 1.04         References
to Sections.

 

Whenever in this Agreement
a particular article, section or other portion thereof is referred to, such reference pertains to the particular article, section
or portion thereof contained herein, unless otherwise indicated.

 

Section 1.05         Currency.

 

Except where otherwise
expressly provided, all amounts in this Agreement are stated and shall be paid in Canadian Dollars.

 

Section 1.06         Gender
and Number.

 

In this Agreement,
unless the context otherwise requires, words importing the singular include the plural and vice versa and words importing gender
include all genders.

 

Section 1.07         Invalidity
of Provisions.

 

Each of the provisions
contained in this Agreement is distinct and severable and a declaration of invalidity or unenforceability of any such provision
or part thereof by a court of competent jurisdiction shall not affect the validity or enforceability of any other provision hereof.

 

Section 1.08         Transition
from GAAP to US GAAP.

 

If the Loan Parties
shall elect as of the end of financial reporting period to prepare their financial statements in accordance with US GAAP, rather
than GAAP, then, following delivery to the Lender of a completed Compliance Certificate attaching the information required to be
delivered for such financial reporting period, the parties hereto shall use their best efforts to amend (in a manner mutually satisfactory
to Lender and Loan Parties) the thresholds or methods of calculation required by Section 6.18 (including any definitions
or components applicable thereto) such that compliance therewith is neither more nor less burdensome (as determined by the Lender
in its sole discretion) to Loan Parties as a result of such conversion to US GAAP and, thereafter, all references in the Loan Documents
to GAAP shall be deemed references to US GAAP.

 

    	 	- 20 -	 

     

    

 

Section 1.09         Amendment
or Waiver.

 

No amendment or waiver
of this Agreement shall be binding unless executed in writing by the party to be bound thereby. No waiver of any provision of this
Agreement shall constitute a waiver of any other provision nor shall any waiver of any provision of this Agreement constitute a
continuing waiver unless otherwise expressly provided.

 

Section 1.10         Non-Business
Days.

 

If any date on which
any payment is due or any action is required to be taken is not a Business Day, the date for payment or taking such action shall
be the next Business Day following the date specified for such payment or action.

 

Section 1.11         Currency
Equivalents

 

For purposes of calculation
and compliance with any limit set forth in Section 6.14 with respect to the amount of Indebtedness, Investment or any other
amount subject to a basket that is incurred or made in a currency other than Canadian Dollars, the equivalent amount in Canadian
Dollars shall be calculated based on the rate of exchange quoted by the Bank of Canada at the close of business on the Business
Day preceding the date the transaction was completed. For purposes of calculation and compliance with the financial covenant set
forth in Section 6.18 with respect to any Unrestricted Cash or Operating Cash Expenditures denominated in a currency other
than Canadian Dollars, the equivalent amount in Canadian Dollars shall be calculated as of the date of determination based on the
rate of exchange used in preparing the applicable financials statements delivered hereunder (or if there is no such rate, the rate
of exchange quoted by the Bank of Canada at the close of business on the Business Day preceding the date of calculation).

 

Section 1.12         German
Terms.

 

In this Agreement,
where it relates to a company incorporated or established under the laws of Germany or a Transaction Security Document governed
by German law, a reference to:

 

		(a)	“receiver”, “manager”, “conservator”,
 “trustee”, “agent”, “custodian”, “monitor”, “liquidator” or other
similar officer includes a reference to an Insolvenzverwalter, vorläufiger Insolvenzverwalter, Sachwalter or vorläufiger
Sachwalter;

 

		(b)	seeking to adjudicate a Loan Party or Subsidiary bankrupt
or insolvent or seeking the “liquidation”, “dissolution”, “winding-up”, reorganization”,
 “arrangement”, “protection”, “relief” or “composition” or initiating or taking
steps to initiate any “Insolvency Proceedings” includes an application or filing for, or an institution of, insolvency
proceedings (Antrag auf Eröffnung eines Insolvenzverfahrens) (including, without limitation, by way of (vorläufige)
Eigenverwaltung or Schutz-schirmverfahren), an ordering of provisional measures according to section 21 of the German
Insolvency Code (Insolvenzordnung) (Anordnung vorläufiger Maßnahmen) or a rejection of insolvency proceedings
on grounds of insufficiency of assets (Abweisung mangels Masse);

 

    	 	- 21 -	 

     

    

 

		(c)	a person being “unable to pay its debts”
or “unable to pay its debts as they fall due”, includes that person being in a state of Zahlungsunfähigkeit
within the meaning of section 17 of the German Insolvency Code (Insolvenzordnung) and a person’s “assets
being less than the aggregate sum of its liabilities” includes that person being in a state of Überschuldung
within the meaning of section 19 of the German Insolvency Code (Insolvenzordnung);

 

		(d)	“management”
of a person includes reference to its Geschäftsführung or Vorstand (as applicable); and

 

		(e)	the “Governing Documents” includes an excerpt
from the competent commercial register (Ausdruck aus dem Handelsregister) of most recent date (not older than 14 days), an up-to-date
copy of the articles of association (Satzung) (as filed with the competent commercial register) or partnership agreement (Gesellschafts-vertrag) and, as applicable, an up-to-date copy of the list of shareholders (Gesellschafterliste) as filed with the competent
commercial register.

 

ARTICLE II.

THE LOANS

 

Section 2.01         The
Commitments.

 

		(a)	Term Loans.
                                         Subject to the terms and conditions of this Agreement, Lender agrees to make (i) a term
                                         loan in Canadian Dollars on the Closing Date in the original principal amount of $12,500,000
                                         (the “Tranche A Term Loan”), and (ii) subject to the Tranche B Conditions
                                         and compliance with all terms, conditions and covenants of this Agreement, at any time
                                         during the Tranche B Availability Period, additional term loans in minimum draws of $1,000,000
                                         in Canadian Dollars after the Closing Date in the original principal amount of up to
                                         $6,250,000 (the “Tranche B Term Loans” and each a “Tranche
                                         B Term Loan”, and together with the Tranche A Term Loan, the “Term
                                         Loans”, and each, a “Term Loan”). Amounts prepaid or repaid
                                         in respect of the Term Loans may not be reborrowed.

 

Section 2.02         Loans.

 

		(a)	Funding of Term Loans. The Tranche A Term Loan
shall be fully funded on the Closing Date. The Tranche B Term Loans, if made, shall be funded in advances after the Closing Date
and during the Tranche B Availability Period. Each advance made under the Tranche B Term Loan shall be added to and form part
of the aggregate amount outstanding under the Term Loans.

 

    	 	- 22 -	 

     

    

 

		(b)	Request for Tranche B Term Loan.

 

		(i)	To request Lender to make the Tranche B Term Loan, Borrower
shall notify Lender of such request by email not later than 1:00 p.m., Toronto, Ontario time, two (2) Business Days before the
date of the proposed Tranche B Term Loan. Such request (a) shall be irrevocable, (b) may be made by a Responsible Officer, and
(c) shall be confirmed promptly by hand delivery or facsimile to Lender of a written Tranche B Term Loan Request, in substantially
the form of Exhibit A and signed by a Responsible Officer (a “Tranche B Term Loan Request”).

 

		(ii)	Such Tranche B Term Loan Request shall include:

 

		(A)	the date the Tranche B Term Loan is requested to be made;

 

		(B)	a certification that each of the Tranche B Conditions
have been met;

 

		(C)	an authorization to deduct the Tranche B Closing Fee
from the proceeds of the Loan;

 

		(D)	the conditions set forth in Section 7.02 are
satisfied; and

 

		(E)	the account to which funds are to be disbursed.

 

Section 2.03         Fees.

 

		(a)	Commitment Fees. Borrower (i) has paid to Lender
prior to the date of this Agreement a commitment fee with respect to the Tranche A Term Loan equal to 0.50% of $12,500,000, which
fee has been fully earned and has been paid on signing the Term Sheet (the “Tranche A Commitment Fee”), and
(ii) agrees to pay to the Lender a commitment fee with respect to the Tranche B Term Loan equal to 0.50% of $6,250,000, which
fee shall be fully earned and payable on the date of the Tranche B Initial Drawdown, if any (the “Tranche B Commitment
Fee”, and together with the Tranche A Commitment Fee, the “Commitment Fee”).

 

		(b)	Closing Fees. Borrower hereby agrees to pay
Lender (i) a closing fee equal to 1.00% of $12,500,000 on the Closing Date, in respect of the Tranche A Term Loan, which fee shall
be fully earned and payable on the Closing Date (the “Tranche A Closing Fee”), and (ii) a closing fee equal
to 1.00% of $6,250,000 payable as a condition to the Tranche B Initial Drawdown, which fee shall be fully earned and payable as
of the date of the Tranche B Initial Drawdown, if any (the “Tranche B Closing Fee”, and collectively with the
Tranche A Closing Fee, the “Closing Fee”).

 

    	 	- 23 -	 

     

    

 

Section 2.04         Payment;
Computation.

 

All fees payable under
this Agreement shall be paid on the dates due, in immediately available Canadian Dollars, to Lender. Fees shall be fully earned
on the dates set forth in this Agreement and shall not be refundable under any circumstances.

 

Section 2.05         Loan
Account.

 

Lender shall maintain,
in accordance with its usual practice, an account on its books in the name of Borrower (the “Loan Account”)
on which Borrower will be charged with all Loans made by Lender to Borrower or for Borrower’s account and with all other
Secured Obligations hereunder or under the other Financing Documents, including, the date, amount and interest rate of each Loan
made to Borrower, accrued interest, fees and expenses, Lender Expenses, and the amount of any sum received by Lender on account
of the Secured Obligations. The entries made in lender’s records with respect to the Loan Account pursuant to this Section
2.05 shall be conclusive evidence (absent manifest error) of the existence and amounts of the obligations recorded therein;
provided that the failure of Lender to maintain such records or any error therein shall not affect in any manner the obligations
of the Borrower to repay the Loans and other Secured Obligations in accordance with this Agreement.

 

ARTICLE III.

PAYMENTS AND PREPAYMENTS

 

Section 3.01         Repayment
of Loans.

 

The Borrower hereby
unconditionally promises to make a monthly repayment of the Term Loans in the principal amount of $378,787.88 on the last Business
Day of each month commencing in October, 2019. Notwithstanding the foregoing and provided that Borrower provides evidence thereof
satisfactory to Lender, if Borrower raises not less than $20,000,000 in new equity prior to the last Business Day of October, 2019,
the first monthly amortization payment may be deferred until the last Business Day of April 2020, and in such case the monthly
repayment amount shall be $462,962.96 payable on the last Business Day of April 2020 and each month thereafter. The principal amounts
drawn, if any, under the Tranche B Term Loan following the Closing Date shall be added to the applicable aforementioned monthly
repayment amounts and repaid in the same manner equally over the number of months remaining until the Maturity Date, and the Lender
shall advise the Borrower of such new monthly repayment amount. The Borrower hereby unconditionally promises to pay to the Lender
the remaining outstanding principal amount of the Term Loans on the Maturity Date.

 

Section 3.02         Interest.

 

		(a)	Term Loans. The Borrower hereby unconditionally
promises to pay to Lender interest on the unpaid principal amount of the Term Loans for the period from and including the date
of each Term Loan to but excluding the date such Term Loan shall be paid in full, at a rate equal to the Term Loan Interest Rate.

 

		(b)	Post-Default Rate. Notwithstanding the foregoing,
the Borrower acknowledges and agrees that if an Event of Default shall have occurred and be continuing, then at the option of
Lender for as long as such Event of Default exists, the unpaid balance of all Loans shall bear interest, to the fullest extent
permitted by law, at a rate equal to 12% per annum (the “Post-Default Rate”), from the date of the Event of
Default has occurred until such Event of Default is cured or waived. The Borrower hereby unconditionally agrees to pay to Lender
interest at the Post- Default Rate, as specified in this paragraph from time to time on demand.

 

    	 	- 24 -	 

     

    

 

		(c)	Payment. The Monthly Interest Amount accrued
on each applicable Term Loan shall be payable monthly in arrears on the last Business Day of each month. Notwithstanding the foregoing,
(i) accrued interest on the principal amount of any Loan repaid or prepaid shall be payable on the date of the payment or prepayment
thereof, and (ii) interest payable at the Post-Default Rate shall be payable on demand.

 

		(d)	For the purposes of the Interest Act (Canada)
and disclosure thereunder, whenever any interest or any fee to be paid hereunder or in connection herewith is to be calculated
on the basis of any period of time that is less than a calendar year, the yearly rate of interest to which the rate used in such
calculation is equivalent is the rate so used multiplied by the actual number of days in the calendar year in which the same is
to be ascertained and divided by 360 or 365, as applicable. The rates of interest under this Agreement are nominal rates, and
not effective rates or yields. The principle of deemed reinvestment of interest does not apply to any interest calculation under
this Agreement.

 

		(e)	If any provision of this Agreement would oblige Borrower
to make any payment of interest or other amount payable to the Lender in an amount or calculated at a rate which would be prohibited
by law or would result in a receipt by that Lender of “interest” at a “criminal rate” (as such terms are
construed under the Criminal Code (Canada)), then, notwithstanding such provision, such amount or rate shall be deemed
to have been adjusted with retroactive effect to the maximum amount or rate of interest, as the case may be, as would not be so
prohibited by Law or so result in a receipt by that Lender of “interest” at a “criminal rate”, such adjustment
to be effected, to the extent necessary (but only to the extent necessary), as follows:

 

		(i)	first, by reducing the amount or rate of interest
required to be paid to the Lender; and

 

		(ii)	thereafter, by reducing any fees, commissions, premiums
and other amounts required to be paid to the Lender which would constitute interest for purposes of section 347 of the Criminal
Code (Canada).

 

    	 	- 25 -	 

     

    

 

		(f)	Calculation of Interest Rate. EACH OF THE LOAN
PARTIES CONFIRMS THAT IT FULLY UNDERSTANDS AND IS ABLE TO CALCULATE THE RATE OF INTEREST APPLICABLE TO EACH OF THE LOANS AND OTHER
SECURED OBLIGATIONS BASED ON THE METHODOLOGY FOR CALCULATING PER ANNUM RATES PROVIDED FOR IN THIS AGREEMENT. Lender agrees that
if requested in writing by a Loan Party it shall calculate the nominal and effective per annum rate of interest on any Loans or
other Secured Obligations outstanding at any time and provide such information to such Loan Party promptly following such request;
provided that any error in any such calculation, or any failure to provide such information on request, shall not relieve such
Loan Party of any of its obligations under this Agreement or any other Financing Document, nor result in any liability to the
Lender. EACH LOAN PARTY HEREBY IRREVOCABLY AGREES NOT TO PLEAD OR ASSERT, WHETHER BY WAY OF DEFENCE OR OTHERWISE, IN ANY PROCEEDING
RELATING TO THE FINANCING DOCUMENTS, THAT THE INTEREST PAYABLE UNDER THE FINANCING DOCUMENTS AND THE CALCULATION THEREOF HAS NOT
BEEN ADEQUATELY DISCLOSED TO THE LOAN PARTIES, WHETHER PURSUANT TO SECTION 4 OF THE INTEREST ACT (CANADA) OR ANY OTHER APPLICABLE
LAW OR LEGAL PRINCIPLE.

 

Section 3.03         End
of Term Payment

 

All amounts advanced
under the Term Loans, including for greater certainty all amounts advanced under the Tranche B Term Loan, shall be subject to an
additional payment in the amount of 2% of the aggregate principal amount of the Term Loans that were advanced (the “End
of Term Payment”) due upon the earlier of (i) the Maturity Date, (ii) the date of prepayment of the Term Loans in full,
(iii) the acceleration of the Term Loan or (iv) the occurrence of a Change of Control.

 

Section 3.04         Optional
Prepayments.

 

Borrower may prepay
the Term Loans, in whole or in part, which prepayments shall be in increments of $500,000 except in connection with prepayment
of all Term Loans in full (including in connection with a prepayment required as a result of a Change of Control, but excepting
prepayments required pursuant to Section 3.05(a) or Section 3.05(b)).

 

Section 3.05         Mandatory
Prepayments.

 

		(a)	Asset Sales. Without limiting the restrictions
pursuant to Section 6.14 with respect to Dispositions, on or before ten (10) days after the receipt of the Net Available
Proceeds from a Disposition, Borrower shall (i) deliver to Lender a certificate of a Responsible Officer, in form and substance
reasonably satisfactory to Lender, containing a statement of the amounts of the cash and non-cash portions of the Net Available
Proceeds of such Disposition and (ii) prepay the Loans in an aggregate amount equal to 100% of the cash portion of the Net Available
Proceeds of the Dispositions, except where such Net Available Proceeds do not exceed $250,000 and are reinvested by a Loan Party
in additional Collateral within 360 days after receipt of such proceeds, provided that any portion of such Disposition proceeds
that has not been reinvested within 360 days after the date of making the Disposition (a “Reinvestment Period”)
shall (x) be deemed to be Net Available Proceeds of a Disposition occurring on the last day of such Reinvestment Period; and (y)
within three (3) Business Days after the last day of such Reinvestment Period, unless otherwise agreed to by the Lender, be used
to prepay the Loans in an aggregate amount equal to 100% of the cash portion of the Net Available Proceeds of the Dispositions.

 

    	 	- 26 -	 

     

    

 

		(b)	Insurance Proceeds. Borrower shall prepay the
Loans in an aggregate amount equal to 100% of the Net Available Proceeds of any Casualty Event, provided that if no Event of Default
has occurred and is continuing and the Loan Parties otherwise haven’t suffered a material impact to the operation of their
business that would take longer than 90 days to remedy, the Loan Parties shall be permitted to apply proceeds of up to $3,500,000
per fiscal year of any insurance, condemnation award or other compensation in respect of a Casualty Event within 90 days after
the receipt thereof by the Loan Parties to repair or replace the affected property, subject to Borrower’s written notice
thereof to Lender promptly upon the occurrence of the Casualty Event. Any proceeds remaining and not used to repair or replace
the affected property within such 90 days shall be applied to prepay the Loans at the Lender’s discretion.

 

		(c)	Change of Control. Upon the occurrence of a
Change of Control, Borrower shall prepay the Loans in full, together with (i) accrued and unpaid interest thereon, and (ii) the
End of Term Payment, together with all other amounts payable under this Agreement, and Lender shall cease to have any commitment
to make Loans under this Agreement.

 

Section 3.06         Application
of Prepayments.

 

Except as otherwise provided in this Agreement,
prepayments pursuant to this Article III shall be applied as follows:

 

		(a)	First, to pay outstanding fees or Lender Expenses;

 

		(b)	Second, to prepay accrued and unpaid interest accrued
on the Term Loans;

 

		(c)	Third, to prepay outstanding principal outstanding
in respect of the Term Loans;

 

		(d)	Fourth, to the payment in full in cash of all other
Secured Obligations; and

 

		(e)	Fifth, to whomsoever is legally entitled thereto or
as a court of competent jurisdiction may direct.

 

Section 3.07         Notice
of Prepayments.

 

Borrower shall notify
Lender by telephone, confirmed by facsimile, of any optional prepayment under this Article III not later than noon Toronto
time, five (5) Business Days before the proposed date of prepayment. Each such notice shall be irrevocable (unless, if Lender so
consents in its reasonable discretion, such notice is a notice of a prepayment which is contingent on the consummation of another
transaction) and shall specify the prepayment date, the principal amount of each Loan or part thereof to be prepaid and (for a
mandatory prepayment) a reasonably detailed calculation of the amount of such prepayment.

 

    	 	- 27 -	 

     

    

 

Section 3.08         Payments
Generally.

 

All payments to be
made by any Loan Party shall be made without condition or deduction for any counterclaim, defense, recoupment or setoff. Except
to the extent otherwise provided herein or in any other Financing Document, the Borrower shall make all payments of principal,
interest and other amounts to be made by any Loan Party under the Financing Documents in immediately available funds, without deduction,
set-off or counterclaim, to Lender at Lender’s Account (except as otherwise expressly provided in this Agreement), prior
to 1:00 p.m. Toronto, Ontario time on the date when due. Any amounts received after such time on any date may, in the discretion
of Lender, be deemed to have been received on the next succeeding Business Day for purposes of calculating interest thereon. All
amounts owing under any Financing Document are payable in Canadian Dollars unless otherwise specified herein. Except to the extent
otherwise provided herein, if any payment under any Financing Document shall be due on a day that is not a Business Day, the date
for payment shall be extended to the next succeeding Business Day and interest thereon shall be payable for the period of such
extension.

 

Section 3.09         Change
in Law and Increased Costs

 

		(a)	If any Change in Law shall:

 

		(i)	impose, modify or deem applicable any reserve, special
deposit, additional capital, compulsory loan, insurance charge or similar requirement against assets of, deposits with or for
the account of, or credit extended by, the Lender;

 

		(ii)	subject the Lender to any Taxes (other than (A) Indemnified
Taxes or (B) Taxes described in clauses (b) through (d) of the definition of Excluded Taxes) on its loans, loan principal, letters
of credit, commitments, or other obligations, or its deposits, reserves or other liabilities or capital attributable thereto;
or

 

		(iii)	impose on the Lender any other condition, cost or
charge (other than Taxes) affecting this Agreement or any Loan hereunder;

 

and the result of any of the foregoing
shall be to increase the cost to the Lender of making, continuing, converting to or maintaining any Loan (or of maintaining its
obligation to make any such Loan) or to reduce the amount of any sum received or receivable by the Lender hereunder (whether of
principal, interest or otherwise), then from time to time Borrower will pay to the Lender such additional amount or amounts as
will compensate the Lender for such additional costs incurred or reduction suffered.

 

    	 	- 28 -	 

     

    

 

		(b)	If the Lender determines that any Change in Law affecting
the Lender or any of its lending offices or its holding company, if any, regarding capital or liquidity requirements, has or would
have the effect of reducing the rate of return on the Lender’s capital or on the capital of its holding company, if any,
as a consequence of this Agreement, its commitment hereunder or the Loans made by the Lender, to a level below that which the
Lender or its holding company would have achieved but for such Change in Law (taking into consideration the Lender’s policies
and the policies of its holding company with respect to capital adequacy or liquidity, as applicable), then from time to time
the Borrower will pay to the Lender in Canadian Dollars such additional amount or amounts as will compensate the Lender or its
holding company for any such reduction suffered.

 

		(c)	A certificate of the Lender setting forth the amount
or amounts necessary to compensate the Lender as specified in clause (a) or (b), as applicable, shall be delivered to Borrower,
and any such certificate shall include a brief description of the Change in Law and a calculation of the amount or amounts necessary
to compensate the Lender and shall, absent manifest error, be prima facie evidence of the amount of such compensation.
In determining such amount, the Lender may use any reasonable method of averaging and attribution that it shall deem applicable.
Borrower shall pay the Lender the amount shown as due on any such certificate within 30 days after receipt thereof.

 

		(d)	Failure or delay on the part of the Lender to demand
compensation pursuant to this section shall not constitute a waiver of the Lender’s right to demand such compensation.

 

Section 3.10         Taxes

 

		(a)	Any and all payments by or on account of any obligation
of a Loan Party under any Financing Document shall be made without deduction or withholding for any Taxes, except as required
by Applicable Law. If any Applicable Law (as determined in the good faith discretion of the applicable Loan Party) requires the
deduction or withholding of any Tax from any such payment by such Loan Party, then the applicable Loan Party shall be entitled
to make such deduction or withholding and shall timely pay the full amount deducted or withheld to the relevant Governmental Authority
in accordance with ApplicableLaw and, if such Tax is an Indemnified, then the sum payable by such Loan Party shall be increased
as necessary so that after such deduction or withholding has been made (including such deductions and withholdings applicable
to additional sums payable under this Section 3.10) the Lender receives an amount equal to the sum it would have received
had no such deduction or withholding been made.

 

		(b)	Payment of Other Taxes by the Borrower: The
Loan Parties shall pay to the relevant Governmental Authority in accordance with Applicable Law, or at the option of the Lender
timely reimburse it for the payment of, any present or future stamp, court or documentary, intangible, recording, filing or similar
Taxes that arise from any payment made under, from the execution, delivery, performance, enforcement or registration of, from
the receipt or perfection of a security interest under, or otherwise with respect to, any Financing Document, except any such
Taxes imposed as a result of a present or former connection between an assignee and the jurisdiction imposing such Taxes (other
than a connection arising from an assignee having executed, delivered, become a party to, performed its obligations under, received
payments under, received or perfected a security interest under, engaged in any transaction pursuant to or enforced any Financing
Document) with respect to an assignment of this Agreement (other than an assignment requested by a Loan Party).

 

    	 	- 29 -	 

     

    

 

		(c)	Indemnification by the Loan Parties. The Loan
Parties shall, jointly and severally, indemnify the Lender, within 10 days after written demand therefor, for the full amount
of any Indemnified Taxes (including Indemnified Taxes imposed or asserted on or attributable to amounts payable under this Section
3.10 payable or paid by the Lender or required to be withheld or deducted from a payment to the Lender and any reasonable
expenses arising therefrom or with respect thereto, whether or not such Indemnified Taxes were correctly or legally imposed or
asserted by the relevant Governmental Authority. A certificate as to the amount of such payment or liability delivered to the
applicable Loan Party by the Lender shall be conclusive, absent manifest error.

 

		(d)	Evidence of Payments. As soon as practicable
after any payment of Taxes by any Loan Party to a Governmental Authority pursuant to this Section 3.10, such Loan Party
shall deliver to the Lender the original or certified copy of a receipt issued by such Governmental Authority evidencing such
payment or other evidence of such payment reasonably satisfactory to the Lender.

 

		(e)	Status of Lender. If the Lender is entitled
to an exemption from or reduction of withholding Tax with respect to payments made under any Financing Document, it shall deliver
to the applicable Loan Party, at the time or times reasonably requested in writing by such Loan Party, such properly completed
and executed documentation so requested as will permit such payments to be made without withholding or at a reduced rate of withholding.
In addition, the Lender, if reasonably requested in writing by any Loan Party, shall deliver such other documentation prescribed
by Applicable Law or so requested by such Loan Party as will enable such Loan Party to determine whether or not the Lender is
subject to backup withholding or information reporting requirements. Notwithstanding anything to the contrary in the preceding
two sentences, the completion, execution and submission of such documentation shall not be required if in the Lender’s reasonable
judgment such completion, execution or submission would subject such Lender to any material unreimbursed cost or expense or would
materially prejudice the legal or commercial position of the Lender.

 

    	 	- 30 -	 

     

    

 

		(f)	Treatment of Certain Refunds. If, following
the imposition of any Taxes on any payment by any Loan Party to the Lender in respect of which any Loan Party is required to make
an additional payment pursuant to this Section 3.10, the Lender receives a refund of Taxes as to which it has been reimbursed,
made whole or indemnified pursuant to this Section 3.10, the Lender will reimburse the Loan Parties an amount equal to
such refund, but only to the extent of indemnity payments made or additional amounts paid by the Loan Parties under this Section
3.10 with respect to Taxes giving rise to such refund, net of all out of pocket expenses (including Taxes) of the Lender and
without interest (other than any net after-tax interest paid by the relevant Governmental Authority with respect to such refund).
Notwithstanding anything to the contrary in this Section 3.10, in no event will the Lender be required to pay any amount
to the Loan Parties pursuant to this Section 3.10, the payment of which would place the Lender in a less favorable net
after-tax position than the Lender would have been in if the indemnification payments or additional amounts giving rise to such
refund had never been paid. Each Loan Party, upon the request of the Lender, agrees to repay to the Lender the amount paid over
to the Loan Parties (plus any penalties, interest or other charges imposed by the relevant Governmental Authority) if the Lender
is required to repay such refund or reduction to such Governmental Authority. This Section 3.10 shall not be construed
to require the Lender to make available its tax returns (or any other information relating to its taxes which it deems confidential)
to the Loan Parties or any other Person.

 

Section 3.11         Illegality

 

If Lender determines that any Law has made
it unlawful, or that any Governmental Authority has asserted that it is unlawful, for Lender or its applicable lending office to
make or maintain any Loan (or to maintain its obligation to make any Loan), or to determine or charge interest rates based upon
any particular rate, then, on notice thereof by such Lender to Borrower, any obligation of such Lender with respect to the activity
that is unlawful shall be suspended until Lender notifies Borrower that the circumstances giving rise to such determination no
longer exist. Upon receipt of such notice, Borrower shall, upon demand from Lender, prepay in order to avoid the activity that
is unlawful. Upon any such prepayment, Borrower shall also pay accrued interest on the amount so prepaid or converted. Lender agrees
to designate a different lending office if such designation will avoid the need for such notice and will not, in the good faith
judgment of Lender, otherwise be materially disadvantageous to Lender.

 

ARTICLE IV.

SECURITY

 

Section 4.01         Security
Documents.

 

On the Closing Date
or, as the case may be, on such later date stated in Section 6.23, as general and continuing security for the due payment and performance
of the Secured Obligations, the following Security Documents will be provided to the Lender:

 

		(a)	a pledge and general security agreement from Borrower
and Parent governed by the laws of Ontario and granting security over all of Borrower’s and Parent’s personal property
and undertaking in Canada (the “Canadian Security Agreement”);

 

		(b)	a Guarantee by Parent, PM Germany and PM USA governed
by the laws of Ontario guaranteeing the Secured Obligations (the “Canadian Guarantee”);

 

    	 	- 31 -	 

     

    

 

		(c)	a global assignment agreement from PM Germany governed
by the laws of Germany and granting security over PM Germany’s intragroup receivables and trade receivables (the “German
Global Assignment Agreement”);

 

		(d)	a pledge agreement from PM Germany governed by the
laws of Germany and granting security over PM Germany’s accounts balances (the “German Account Pledge Agreement”);

 

		(e)	a pledge agreement from Borrower governed by the laws
of Germany and granting security over all of the Borrower’s equity interest in PM Germany (the “German Share Pledge
Agreement” and collectively with the German Global Assignment” and the German Account Pledge Agreement, the “German
Security Agreements”);

 

		(f)	a pledge and security agreement from the Borrower
and PM USA governed by the laws of New York and granting security over (i) all of the Borrower’s shares in PM USA and (ii)
PM USA’s personal property and undertaking in the United States of America (the “USA Security Agreement”);

 

		(g)	an intellectual property security agreement for all
Canadian Intellectual Property (the “Canadian IP Security Agreement”);

 

		(h)	an intellectual property security agreement for all
United States Intellectual Property (the “US IP Security Agreement”);

 

		(i)	a Collateral Access Agreement for the Borrower’s
Mississauga, Ontario location;

 

		(j)	a Control Agreement for all Securities Accounts, Deposit
Accounts and other Investment Property held by each Loan Party on the Closing Date, in each case other than in respect of Excluded
Accounts; and

 

		(k)	any other Security Documents reasonably requested
by the Lender.

 

Section 4.02         Control
of Collateral; Control Agreements.

 

Borrower shall maintain
all Deposit Accounts with financial institutions that are acceptable to the Lender. If from time to time any Collateral consists
of property or rights of any Loan Party in which the perfection or priority of Lender’s security interest is dependent upon
Lender’s gaining control of such Collateral (including Securities Accounts, other Investment Property or Deposit Accounts)
or otherwise consists of a Deposit Account located in a jurisdiction for which control is not required for perfection, in each
case other than Excluded Accounts, Borrower shall notify Lender and deliver the appropriate Control Agreements, and each Loan Party
shall do the same with respect to any property securing the applicable Guarantee. No Control Agreement in respect of any Deposit
Account, Securities Accounts or other Investment Property shall be modified by any Loan Party without the prior written consent
of Lender.

 

    	 	- 32 -	 

     

    

 

Section 4.03         Guarantors

 

If at any time Borrower
owns, establishes or acquires a wholly-owned Material Subsidiary (including without limitation any wholly-owned Subsidiary that
exists on the Closing Date and becomes a Material Subsidiary), Borrower shall immediately cause such Subsidiary to become a Guarantor
hereunder, and deliver such Guarantee and other Security Documents so as to reflect and replicate the security delivered by Borrower
on the Closing Date and the intent of Section 4.05(b). The Borrower shall also deliver or cause the delivery of a pledge
of all of the issued and outstanding equity of such new Guarantor concurrently therewith, together with any certificates representing
such equity and corresponding powers of attorney in respect of such certificates.

 

Section 4.04         Real
Estate

 

Borrower shall:

 

		(a)	notify the Lender within ten Business Days of any
Loan Party acquiring any freehold, leasehold, licence or other similar interest in real property after the Closing Date;

 

		(b)	in the case of any freehold interest in real property
located in Canada, Europe or the United States with a value in excess of $500,000, grant a fixed charge to the Lender on any such
real property interest (together with any title opinions or title insurance relating thereto in form and substance acceptable
to the Lender); and

 

		(c)	in the case of any leasehold interest in real property,
use commercially reasonable efforts to obtain a Collateral Access Agreement if requested by the Lender.

 

Section 4.05         Delivery
of Additional Documentation Required.

 

		(a)	At any time upon the written request of Lender, each
Loan Party shall execute and deliver to Lender, any and all security agreements, pledges, assignments, endorsements of certificates
of title, bailee acknowledgments and all other documents (the “Additional Documents”) that Lender may request
in its sole discretion, each in form and substance satisfactory to Lender, to maintain perfection and protect the priority of
Lender’s Liens in the Collateral (whether now owned or hereafter arising or acquired), to create and perfect Liens in favor
of Lender in any real property acquired after the Closing Date, and in order to fully consummate all of the transactions contemplated
hereby and under the other Financing Documents. Each Loan Party authorizes Lender to execute any such Additional Documents in
such Loan Party’s name and authorize Lender to file such executed Additional Documents in any appropriate filing office.

 

		(b)	It is the intention of the parties hereunder that
Borrower and each Material Subsidiary shall grant security over all present and after-acquired personal property and material
real estate described in Section 4.05 in the applicable jurisdiction(s) as determined by the Lender, and agree to promptly
deliver all to the Lender all Additional Documents that may be required from time to time to effect such intention.

 

    	 	- 33 -	 

     

    

 

Section 4.06         Right
to Inspect.

 

Lender (through any
of its officers, employees, or agents) shall have the right, from time to time hereafter (but, provided no Event of Default has
occurred and is continuing, not more than once per fiscal year), at reasonable times and upon reasonable notice, during business
hours, to inspect the books and records of each Loan Party and to check, test, and appraise the Collateral in order to verify the
Loan Parties’ financial condition or the amount, quality, value, condition of, or any other matter relating to, the Collateral.

 

ARTICLE V.

REPRESENTATIONS AND WARRANTIES

 

Each Loan Party represents and warrants
to Lender that:

 

Section 5.01         Incorporation
and Status.

 

Each Loan Party is
duly incorporated and organized, and is validly existing under its jurisdiction of organization. Such Loan Party is duly registered,
licensed or qualified as a foreign corporation, and is up to date in the filing of all corporate and similar returns and is in
good standing under the laws of those jurisdictions where it operates and where failure to be so registered, licensed, qualified
or up to date would have a Material Adverse Effect on it. . For the purposes of Regulation (EU) 2015/848 of the European Parliament
and of the Council of 20 May 2015 on insolvency proceedings (recast), the Centre of Main Interests of each Loan Party incorporated
in a member state of the European Union is situated in its jurisdiction of organization and each Loan Party incorporated in a member
state of the European Union has, and at all times during the three (3) month period prior, had, no Establishment in any other jurisdiction.

 

Section 5.02         Corporate
Power and Due Authorization.

 

Each Loan Party has
the corporate power and capacity to enter into, and to perform its obligations under this Agreement and the Financing Documents,
to which it is a party, as applicable. Each of this Agreement and the Financing Documents to which it is a party has been duly
authorized, executed and delivered by such Loan Party (including, without limitation, receipt of all requisite board, stockholder
and member approvals) and is a valid and binding obligation of such Loan Party enforceable in accordance with its terms, subject
to the usual exceptions as to bankruptcy and the availability of equitable remedies.

 

Section 5.03         Business
of the Loan Parties.

 

The Loan Parties has
the corporate or other applicable power and capacity to own, lease or license its assets and to carry on its business.

 

    	 	- 34 -	 

     

    

 

Section 5.04         No
Contravention.

 

Neither the entering
into and performing under this Agreement or the Financing Documents or the performance by each Loan Party of any of its respective
obligations hereunder or thereunder will contravene, breach, result in any default or result in any acceleration, bonus or benefit
to any other party under Governing Documents of such Loan Party or under any mortgage, lease, license agreement, supply agreement,
contract, agreement, other legally binding instrument, license, permit, Regulatory Required Permit, statute, regulation, order,
judgment, decree or law to which it is a party or by which it may be bound.

 

Section 5.05         Not
Insolvent.

 

No Loan Party nor any
of their predecessors where applicable (a) has committed any act of bankruptcy or initiated or taken steps to initiate any Insolvency
Proceeding, (b) (i) is insolvent, (ii) is unable for any reason to unable to meet its obligations as they generally become due,
(iii) has ceased paying its current obligations or (iv) is a Person the aggregate of whose property is not, at fair valuation,
sufficient, or, if disposed of at a fairly conducted sale under legal process, would not be sufficient to pay all its obligations
due and accruing due, (c) has proposed, or given notice of its intention to propose, a compromise or arrangement to its creditors
generally, including pursuant to any Insolvency Legislation, or (d) has any petition for a receiving order in bankruptcy filed
against it, made a voluntary assignment in bankruptcy, taken any proceeding with respect to any compromise or arrangement, taken
any proceeding to have itself declared bankrupt or wound-up, taken any proceeding to have a receiver appointed of any part of its
assets, has had any encumbrancer take possession of any of its property.

 

Section 5.06         Approvals
and Consents.

 

No authorization, consent
or approval of, or filing with or notice to, any governmental agency, regulatory body, court or other person is required in connection
with the execution, delivery or performance and compliance with the terms of this Agreement and the Financing Documents to which
any Loan Party is a party nor will such performance and compliance contravene any statute, rule or regulation binding on any Loan
Party.

 

Section 5.07         Welfare
and Pension Plans.

 

Each Loan Party has
adopted all Welfare Plans required by Law and each of such plans has been maintained in compliance with such laws in all material
respects including, without limitation, all requirements relating to employee participation, funding, investment of funds, benefits
and transactions with Loan Parties and persons related to them. No Loan Party has a material contingent liability with respect
to any post-retirement benefit under a Welfare Plan. No Loan Party maintains a Pension Plan.

 

Section 5.08         Changes
Since Date of Financial Statements.

 

No Loan Party is a
party to nor is bound by any contract, agreement or commitment that materially adversely affects or could reasonably be expected
to materially adversely affect such Loan Party’s business or its financial condition or any of its assets. Additionally,
since December 31, 2017, no event has (or would reasonably be expected to) give rise to a Material Adverse Effect, and no Loan
Party has (except as set forth on Schedule 5.08):

 

    	 	- 35 -	 

     

    

 

		(a)	other than in the ordinary course and consistent with
past practices of the Loan Parties, sold, transferred or otherwise disposed of, or created, assumed or permitted any encumbrance
on or in respect of, its property or assets or any part thereof other than Permitted Encumbrances;

 

		(b)	incurred, assumed or become subject to any material
liability except in the ordinary course of business;

 

		(c)	suffered a change in assets, liabilities, financial
condition, prospects or operations of the Loan Parties, from that reflected in the financial statements as of the date set forth
above, other than changes in the ordinary course, which individually or in the aggregate has had or could reasonably be expected
to have a Material Adverse Effect;

 

		(d)	suffered any damage, destruction or loss, whether
or not covered by insurance, which would materially and adversely affecting the properties, business or prospects or financial
condition of the Loan Parties;

 

		(e)	cancelled or released any debts or claims or waived
or surrendered any rights which, in the aggregate, are material;

 

		(f)	suffered the resignation or termination of any officer,
key employee or group of employees thereof;

 

		(g)	made any material change to any material compensation
agreement or other Material Agreement with any employee, officer, director or stockholder;

 

		(h)	assigned or granted any exclusive license or transferred
any Material Intellectual Property or material Regulatory Required Permit;

 

		(i)	made any change to any Material Agreement to which
any Loan Party is a party or by which it is bound which materially and adversely affects the business, assets, liabilities, financial
condition, operations or prospects of the Loan Parties; or

 

		(j)	except as described in the Loan Parties’ consolidated
financial statements, made any change in its accounting principles and practices as theretofore applied including, without limitation,
the basis upon which its assets and liabilities are recorded on its books and its earnings, profits and losses are ascertained.

 

Section 5.09         No
Default Under Agreements.

 

No Loan Party is in
default or breach of any Material Agreement to which it is a party which default or breach has had or could reasonably be expected
to have a Material Adverse Effect, no event has occurred that after notice or the passage of time, or both, would constitute such
a default or breach, and all Material Agreements are in good standing in all material respects. A list of all Material Agreements,
including all material supply agreements, is set forth on Schedule 5.09.

 

    	 	- 36 -	 

     

    

 

Section 5.10         Title
to Assets.

 

The Loan Parties are
the absolute beneficial owners of and have good and marketable title, free of all charges except for Permitted Encumbrances, to
all the material assets owned by them and used in connection with the Loan Parties’ business.

 

Section 5.11         Financial
Matters.

 

The audited consolidated
financial statements of Borrower for the fiscal year ended 2017 and the unaudited consolidated financial statements of Borrower
for the periods through March 31, 2018 present fairly in all material respects the consolidated financial position of Borrower
on a consolidated basis as at the dates indicated and the results of its operations and changes in its financial position for the
periods specified and reflect all material liabilities (absolute, accrued, contingent or otherwise) of Borrower as of the dates
thereof and such financial statements have been prepared in conformity with GAAP applied, except as otherwise stated therein, on
a consistent basis.

 

Section 5.12         No
Material Adverse Change

 

Since December 31, 2017, there has been
no Material Adverse Change.

 

Section 5.13         Environmental
Matters.

 

(a) The assets of each
Loan Party have not been used by a Loan Party in the disposal of, or to produce, store, handle, treat, release, or transport, any
Hazardous Materials, where such production, storage, handling, treatment, release or transport was in violation, in any material
respect, of applicable Environmental Law, (b) to Borrower’s knowledge, no properties or assets of any Loan Party has ever
been designated or identified in any manner pursuant to any environmental protection statute as a Hazardous Materials disposal
site, (c) no Loan Party has received notice that a Lien arising under any Environmental Law has attached to any revenues or to
any Property owned or operated by a Loan Party, and (d) no Loan Party has received a summons, citation, notice, or directive from
any federal or state governmental agency concerning any action or omission by any Loan Party resulting in the releasing or disposing
of Hazardous Materials into the environment. As used herein, “Hazardous Materials” means (A) substances that are defined
or listed in, or otherwise classified pursuant to, any Applicable Laws or regulations as “hazardous substances,” “hazardous
materials,” “hazardous wastes,” “toxic substances,” or any other formulation intended to define,
list, or classify substances by reason of deleterious properties such as ignitability, corrosivity, reactivity, carcinogenicity,
reproductive toxicity, or “EP toxicity”, (B) oil, petroleum, or petroleum derived substances, natural gas, natural
gas liquids, synthetic gas, drilling fluids, produced waters, and other wastes associated with the exploration, development, or
production of crude oil, natural gas, or geothermal resources, (C) any flammable substances or explosives or any radioactive materials,
and (D) asbestos in any form or electrical equipment that contains any oil or dielectric fluid containing levels of polychlorinated
biphenyls in excess of 50 parts per million.

 

    	 	- 37 -	 

     

    

 

Section 5.14         Assets
in Good Condition.

 

All the material physical
assets of each Loan Party are in good operating condition and in a state of good maintenance and repair subject to the usual wear
and tear for assets of that age.

 

Section 5.15         Licenses
and Agreements.

 

Each of the material
licenses and agreements to which any Loan Party are a party is in good standing and in full force and effect, and neither a Loan
Party nor, to the best of the knowledge, information and belief of the Loan Parties, after due inquiry, any other party thereto,
is in breach of any material covenants, conditions or obligations contained therein.

 

Section 5.16         Tax
Matters.

 

Each Loan Party has
filed all federal, provincial, state and other (including foreign) Tax returns which are required to be filed, and have paid all
Taxes as shown on said returns, as well as all other Taxes to the extent that they have become due, unless being contested in good
faith with appropriate reserves. All Tax liabilities of each Loan Party are adequately provided for on such Loan Party’s
books, including interest and penalties. No Tax liability has been asserted by taxing authorities for Taxes in excess of those
already paid, and no taxing authority has notified any Loan Party of any material deficiency in any federal, state and other Tax
returns. Notwithstanding the foregoing, each of the representations set forth in this Section 5.16 shall be deemed to be satisfied
where the potential liability does not exceed, and could not reasonably be expected to exceed, $20,000.00; provided that any such
liability under such threshold known to the Loan Parties as of the Closing Date is set forth on Schedule 5.16 hereto.

 

Section 5.17         Insurance.

 

Each Loan Party maintains
insurance for risks and in amounts customary for prudent companies in the Loan Parties’ industry and owners of comparable
assets with responsible insurers against such risks. No Loan Party is in default with respect to any of the material provisions
contained in any current insurance policy or has failed to give any notice or pay any premium or present any unsettled claim under
any current insurance policy in a due and timely fashion.

 

    	 	- 38 -	 

     

    

 

Section 5.18         Intellectual
Property.

 

The Loan Parties own
or possess all their Material Intellectual Property without any known conflict with, or infringement of, the rights of others.
To the knowledge of the Loan Parties, no Product or service marketed or sold (or proposed to be marketed or sold) by any Loan Party
violates or will violate any license or infringes or will infringe in any material manner any intellectual property rights of any
other party. Schedule 5.18 lists (i) all applications and registrations of Intellectual Property of the Loan Parties as
of the date hereof and identifies which of such Intellectual Property is Material Intellectual Property as of the date hereof,
(ii) all in-bound license or sublicense agreements for Material Intellectual Property to which a Loan Party is a party as of the
date hereof, and (iii) all material out-bound license or sublicense agreements to which a Loan Party is a party as of the date
hereof (in the case of (ii) and (iii) except for licenses of commercially available software or information technology services).
Other than as set forth on Schedule 5.18, or with respect to commercially available software products or information technology
services, as of the date hereof there are no outstanding options, licenses, agreements, claims, encumbrances or shared ownership
interests of any kind relating to the Material Intellectual Property owned by any Loan Party, nor is any Loan Party bound by or
a party to any options, licenses or agreements of any kind with respect to any patents, trademarks, service marks, trade names,
copyrights, trade secrets, licenses, information, proprietary rights and processes of any other Person. With respect to any Material
Intellectual Property that is a license agreement, Schedule 5.18 indicates as of the date hereof (A) the name of the licensor,
(B) the name and date of the agreement pursuant to which such item of Material Intellectual Property is licensed, and (C) whether
or not such license agreement grants an exclusive license to any Loan Party. No Loan Party has received any written communications
alleging that such Loan Party has violated or, by conducting its business, would violate any of the patents, trademarks, service
marks, tradenames, copyrights, trade secrets, mask works or other proprietary rights or processes of any other Person. It will
not be necessary to use any inventions of any of such Loan Party’s employees or consultants (or Persons it currently intends
to hire) made prior to their employment by such Loan Party. Each employee or consultant engaged in research and development has
entered into an invention assignment agreement or similar agreement with such Loan Party with respect to all intellectual property
rights he or she develops pursuant to his or her employment or engagement to the applicable Loan Party. No Subsidiary that is not
a Loan Party owns any Material Intellectual Property.

 

Section 5.19         Permits.

 

The Loan Parties hold
all permits (including Regulatory Required Permits), licenses, approvals, consents, authorizations, registrations, certificates
and franchises of governmental agencies or regulatory bodies required to own its properties and assets and to carry on its business,
except for any of the foregoing where the failure to hold the same would not have a Material Adverse Effect (the “Permits”),
and a list of all such Permits is set forth on Schedule 5.19. All the Permits are in full force and effect; each Loan Party
is in compliance in all material respects with all the terms and conditions relating to the Permits; and there are no proceedings
in progress, pending or, to such Loan Party’s knowledge, threatened, that may result in revocation, cancellation, suspension,
rescission or any adverse modification of any of the Permits nor, to the best of the knowledge, information and belief of such
Loan Party, after due inquiry, are there any facts upon which proceedings could reasonably be based.

 

Section 5.20         Regulatory
Required Permits.

 

With respect to any
Product or service of any Loan Party, (i) each Loan Party has received, and such Product or service is the subject of, all Regulatory
Required Permits needed in connection with the testing, manufacture, marketing or sale of such Product or conduct of such service
as currently being conducted by or on behalf of such Loan Party, and (ii) such Product is being tested, manufactured, marketed
or sold, as the case may be, in material compliance with all Applicable Laws and Regulatory Required Permits, and such Loan Party
has not received any notice from any applicable Regulatory Authority or any other Governmental Authority that such Regulatory Authority
or Governmental Authority is conducting a material investigation or review of such Loan Party.

 

    	 	- 39 -	 

     

    

 

Section 5.21         Compliance
with Laws and Litigation.

 

		(a)	Each Loan Party is each conducting its business in compliance with all Applicable Laws,
                                                                                 including for greater certainty all Healthcare Laws, of each jurisdiction in which its business is carried on, except where
                                                                                 the failure to be in such compliance would not have a Material Adverse Effect; and

 

		(b)	There is no court, administrative, regulatory or similar
proceeding (whether civil, quasi-criminal or criminal); arbitration or other dispute settlement procedure; investigation or enquiry
by any governmental, administrative, regulatory or similar body; or any similar matter or proceeding (collectively, “Proceedings”)
against or involving any Loan Party or any of their officers or directors (whether in progress, pending or, to the best of the
knowledge, information and belief of such Loan Party after due inquiry, threatened); no event has occurred that might give rise
to any Proceedings and such Loan Party is not aware of any existing grounds on which such Proceedings might be commenced and there
is no judgment, decree, injunction, rule, award or order of any court, government department, board, commission, agency, arbitrator
or similar body outstanding against such Loan Party or its officers or directors.

 

Section 5.22         Material
Facts Disclosed.

 

None of the statements,
documents, certificates or other items prepared or supplied by any Loan Party with respect to the transactions contemplated hereby
contains an untrue statement of a material fact, or fails to disclose a fact that is necessary to be made in order for any material
statement not to be misleading.

 

Section 5.23         No
Rights to Acquire Assets.

 

No person has any agreement
or option or right or privilege (whether pre-emptive or contractual) capable of becoming an agreement for the purchase of any assets
of any Loan Party.

 

Section 5.24         No
Rights to Provide Financial Advisory Services.

 

No person has any agreement
or option, or right or privilege (whether pre-emptive or contractual) capable of becoming an agreement for the provision of financial
advisory services to any Loan Party.

 

Section 5.25         Chief
Executive Office and Location of Assets.

 

There is no location
at which any Loan Party has any assets (except for Products in transit) other than those locations listed on Schedule 5.25.
The chief executive office, registered office, principal place of business and the place where each Loan Party keeps its books
and records is located and specifically identified on Schedule 5.25. The locations of any assets stored with a bailee or
similar entity are located on Schedule 5.25.

 

    	 	- 40 -	 

     

    

 

Section 5.26         Minute
Books.

 

The minute books, stock
certificate books and stock transfer ledgers of each Loan Party are true, correct, complete and up-to-date and contain the minutes
of all meetings, and all resolutions, of the board of directors thereof (and all committees thereof) and shareholders thereof,
except that minutes of the most recent meeting of the directors may not be included or may be included in such minute books in
draft form.

 

Section 5.27         Use
of Proceeds; Margin Stock.

 

The proceeds of any
of the Loans will be used solely as provided in this Agreement, and none of such proceeds will be used (i) for the purpose of purchasing
or carrying any “margin stock” as defined in Regulations T, U or X of the Board of Governors of the Federal Reserve
System (12 C.F.R. Parts 220, 221 and 224), (ii) for the purpose of maintaining, reducing or retiring any indebtedness which was
originally incurred to purchase or carry a “margin stock,” or (iii) for any other purpose which might constitute this
transaction a “purpose credit” within the meaning of Regulations T, U or X. No Loan Party is engaged in the business
of extending credit for the purpose, whether immediate, incidental or ultimate, of buying or carrying “margin stock.”
No Loan Party nor any Person acting on behalf of any Loan Party has taken or will take any action which might cause any of the
Financing Documents to violate Regulations T, U or X, or any other regulations of the Board of Governors of the Federal Reserve
System or to violate the Securities Exchange Act of 1934, as amended, or any rule or regulation thereunder, in each case as now
in effect or as the same may hereafter be in effect.

 

Section 5.28         Investment
Company Act.

 

Neither any Loan Party
or any Person Controlling a Loan Party is or is required to be registered as an “investment company” under the Investment
Company Act of 1940.

 

Section 5.29         Bank
Accounts.

 

Schedule 5.27
lists, as of the Closing Date, all banks and other financial institutions at which any Loan Party maintains Deposit Account or
Securities Accounts, and such Schedule correctly identifies the name and address of each depository or intermediary, the name in
which such account is held, a description of the purpose of the account and the complete account number of such account.

 

Section 5.30         Shares
and Corporate Structure.

 

		(a)	The corporate structure of the Loan Parties and their
Subsidiaries and shareholders is, as at the Closing Date, as set out in Schedule 5.30, which Schedule contains the authorized
capital of the Parent, Borrower and their respective Subsidiaries and the number of issued and outstanding shares and the beneficial
owners thereof at such time. Each of the Subsidiaries is, directly or indirectly, wholly-owned by one or more a Loan Party or
a Subsidiary. No Loan Party is a participant in any joint venture, partnership, limited liability company or similar arrangement.
Except as set forth on Schedule since its inception, no Loan Party has consolidated or merged with, or acquired assets outside
the ordinary course of, or acquired the stock of or any interest in any Person.

 

    	 	- 41 -	 

     

    

 

		(b)	No Person (other than the Lender) will have an agreement
or option or any other right or privilege (whether by law, pre-emptive or contractual) capable of becoming an agreement or option,
including convertible securities, warrants or convertible obligations of any nature, for the purchase, subscription, allotment
or issuance of any unissued shares in the capital of the Borrower except as described in Schedule 5.30.

 

		(c)	To the extent applicable and subject to satisfaction
of all obligations pursuant to Section 6.23, each Loan Party has full power and authority to create a lien on the Shares and no
disability or contractual obligation or restriction exists, that would prohibit such Loan Party from pledging the Shares pursuant
to this Agreement or the Security Agreements. There are no subscriptions, warrants, rights of first refusal or other restrictions
on transfer relative to, or options exercisable with respect to the Shares. The Shares have been and will be duly authorized and
(to the extent such concepts are applicable under the laws under which the applicable entity was formed) validly issued, fully
paid and non-assessable. The Shares are not the subject of any present or threatened (in writing) suit, action, arbitration, administrative
or other proceeding, and no Loan Party knows of any reasonable grounds for the institution of any such proceedings.

 

Section 5.31         Liabilities.

 

No Loan Party has any
material liabilities and, to the best of its knowledge no material contingent liabilities, not disclosed in the financial statements
of such Loan Party, except (i) current liabilities incurred in the ordinary course of business to the date of the financial statements,
which have not been, either in any individual case or in the aggregate, materially adverse and (ii) liabilities of a type not required
by GAAP to be reflected in financial statements.

 

Section 5.32         Employee
Matters.

 

No Loan Party is a
party to or bound by any currently effective employment contract, deferred compensation arrangement, bonus plan, incentive plan,
profit sharing plan, retirement agreement or other employee compensation plan or agreement, except as set forth on Schedule
5.32. No employee of a Loan Party has been granted the right to continued employment by such Loan Party or to any material
compensation following termination of employment with such Loan Party, except as set forth on Schedule 5.32. To each Loan
Party’s knowledge, no employee of any Loan Party, nor any consultant with whom such Loan Party has contracted, is in violation
of any term of any employment contract, proprietary information agreement or any other agreement relating to the right of any such
individual to be employed by, or to contract with, such Loan Party; and to each Loan Party’s knowledge the continued employment
by such Loan Party of its respective present employees, and the performance of such Loan Party’s contracts with its independent
contractors, will not result in any such violation, and no such Loan Party has received any notice alleging that such violation
has occurred. No Loan Party is aware that any officer, key employee or group of employees of such Loan Party intends to terminate
his, her or their employment with any Loan Party, as applicable, nor does any Loan Party have a present intention to terminate
the employment of any such officer, key employee or group of employees. Each former employee of each Loan Party whose employment
was terminated by such Loan Party has entered into an agreement with such Loan Party providing for the full release of any claims
against such Loan Party or any related party arising out of such employment. There are no actions pending, or to such Loan Party’s
knowledge, threatened, by any former or current employee concerning such person’s employment by such Loan Party.

 

    	 	- 42 -	 

     

    

 

Section 5.33         Non-Arm’s
Length Transactions

 

All agreements, arrangement
or transactions between any Loan Party, on the one hand, and any Affiliate of or other Person not dealing at arm’s length
with the Borrower (other than ordinary course arrangements with any employee, management or director of the Borrower), on the other
hand, in existence as of the Closing Date are set forth on Schedule 5.33.

 

Section 5.34         Description
of Real Property

 

Schedule 5.34
contains a description as of the Closing Date of (a) all real property owned by the Loan Parties (including municipal addresses,
legal description (to the extent available), a brief description of such property and its use), and (b) all real property leased
by the Loan Parties (including municipal addresses, legal description (to the extent available), the name of the landlord, the
term and any renewal rights under the applicable lease and a brief description of such property and its use).

 

Section 5.35         Application
of Section to New Subsidiaries

 

To the extent any Loan
Party forms or acquires any Subsidiary that becomes a Loan Party after the Closing Date, the representations and warranties in
this section shall be made with respect to such Subsidiary as if it were a Loan Party for purposes hereof from and after the date
of such formation or acquisition.

 

ARTICLE VI.

COVENANTS

 

For as long as the
Secured Obligations remain outstanding or Lender has any commitment to extend credit, each Loan Party agrees as follows:

 

Section 6.01         Use
of Proceeds.

 

The Borrower shall
only use the proceeds of the Loans to refinance the Existing Loan Facility and for general corporate and working capital purposes.

 

Section 6.02         Payment
of Principal and Interest; Secured Obligations.

 

Each of the Loan Parties
will duly and punctually pay the Secured Obligations, including, without limitation, the principal and interest accrued on the
Loans at the time and in the manner specified herein.

 

    	 	- 43 -	 

     

    

 

Section 6.03         Lender
Expenses.

 

Each of the Loan Parties shall pay all Lender
Expenses on demand.

 

Section 6.04         Compliance
with Laws; Permits; Corporate Existence.

 

Each of the Loan Parties
shall (and shall cause its Subsidiaries, if any, to) maintain its corporate existence (other than in accordance with Section
6.14(d) or Section 6.14(e)), carry on and conduct its business in a proper and business-like manner, take all reasonable
action to maintain all rights, privileges and franchises necessary or desirable in the normal conduct of its business, including
all Permits, and comply with all Applicable Laws, in each case in all material respects. Each of the Loan Parties shall also forthwith
notify Lender in writing of the dissolution or wind-up of any existing Loan Party or Subsidiary or the creation or acquisition
of any new Subsidiary after the date hereof (and whether such Subsidiary is a Material Subsidiary).

 

Section 6.05         Delivery
of Collateral and Perfection.

 

Each Loan Party shall
take such actions at the sole cost and expense of such Loan Party, as may be required or desirable and as requested by Lender,
to preserve, protect or perfect the security interests of Lender with respect to the Collateral.

 

Section 6.06         Collateral.

 

Each Loan Party will
defend the Collateral against, and will take such other action as is necessary to remove, any and all security interests on and
claims in respect of the Collateral other than the security interests created by this Agreement and Permitted Encumbrances.

 

Section 6.07         Operating
Leases.

 

Neither a Loan Party
nor any of its Subsidiaries will enter into or maintain operating leases (other than real property leases) such that the aggregate
annual consolidated expenditure on such operating leases would be greater than $500,000.

 

Section 6.08         Insurance.

 

Each Loan Party shall
(and shall cause each of its Subsidiaries to) maintain insurance for risks and in amounts customary for prudent companies in the
Loan Parties’ industry and owners of comparable assets with responsible insurers against such risks, which insurance shall
be satisfactory to Lender, including but not limited to, business interruption, with Lender being named as a lender first loss
payee and mortgagee with respect to any commercial property insurance of each Loan Party and as additional insured with respect
to any general liability insurance of each Loan Party, and shall provide appropriate endorsements. Borrower shall promptly notify
Lender of the occurrence of any event which would negatively affect any insurance coverage. If a Loan Party does not maintain insurance
as required under this Section 6.08 or pay any amount or furnish required proof of payment to Lender, Lender may make all
or part of such payment or obtain such insurance policies required in this Section 6.08.

 

    	 	- 44 -	 

     

    

 

Section 6.09         Transactions
with Affiliates.

 

No Loan Party shall
or shall permit any of its Subsidiaries to enter into any transaction with any officer, director, employee, shareholder or any
Person not dealing at arm’s length or any Affiliate of any of the foregoing (specifically excluding any employment or option
agreement or intercompany indebtedness or transactions between a Loan Party and any of its Subsidiaries) unless such transaction
is on terms no less favorable to such Loan Party than would be obtainable in an arm’s length transaction. The Loan Parties
shall provide the Lender with evidence of compliance with this covenant upon request.

 

Section 6.10         Material
Agreement.

 

Each Loan Party shall
observe each term, covenant and agreement contained in the Material Agreements, except to the extent that any non-compliance could
not reasonably be expected to result in Material Adverse Effect. At Lender’s request, each Loan Party shall provide copies
of any Material Agreements entered into after the Closing Date.

 

Section 6.11         Reporting.

 

Parent shall prepare and provide to Lender
with respect to Parent and its Subsidiaries (a) monthly unaudited consolidated financial statements within 30 days of the end of
each month accompanied by a Compliance Certificate as referred to in Section 6.18, (b) quarterly unaudited consolidated financial
statements within the earlier of fourty-five (45) days of the end of each fiscal quarter (including, without limitation, the last
fiscal quarter) or the date that such financial statements are filed publicly, (c) audited consolidated financial statements within
the earlier of one hundred and twenty (120) days of the Parent’s fiscal year end or the date such financial statements are
filed publicly, such audited financial statements to be accompanied by a report and opinion of an independent certified public
accountant acceptable to Lender, which report and opinion shall be prepared in accordance with GAAP and shall not be subject to
any qualification or exception, and (d) as soon as available, but in any event not later the last day of each fiscal year, the
Budget for the next fiscal year. Parent shall provide, upon request by the Lender, general ledger accounts and any board and board
subcommittee materials and shall provide online access to the Lender to quarterly board materials.

 

Section 6.12         Healthcare
Regulatory Matters.

 

Each Loan Party:

 

		(a)	shall notify Lender promptly, and in any event within
ten (10) Business Days, after receiving a written notice of or otherwise becoming aware of or determining that any of the following
has occurred and would reasonably be expected to cause a Material Adverse Effect (each, a “Regulatory Reporting Event”
and collectively, the “Regulatory Reporting Events”): (i) any Governmental Authority or Regulatory Authority
is conducting or has conducted (A) if applicable, an investigation of any of the Loan Parties’ or their respective Subsidiaries’
manufacturing facilities and processes for any Product which investigation has disclosed any material deficiencies or violations
of Laws and/or the Regulatory Required Permits related thereto or (B) an investigation or review of any Regulatory Required Permit
(other than routine reviews in the ordinary course of business associated with the renewal of a Regulatory Required Permit), (ii)
development, testing, and/or manufacturing of any Product that is material to the Loan Parties business (taken as a whole) should
cease, (iii) if a Product that is material to the Loan Parties business (taken as a whole) has been approved for marketing and
sale, any marketing or sales of such Product should cease or such Product should be withdrawn from the marketplace, or (iv) any
Regulatory Required Permit has been revoked or withdrawn. Each Loan Party shall provide to Lender such further information (including
copies of such documentation) as Lender may reasonably request with respect to any such Regulatory Reporting Event; and

 

    	 	- 45 -	 

     

    

 

		(b)	shall and shall cause each other Loan Party to, obtain
all Regulatory Required Permits necessary for compliance in all material respects with Laws with respect to testing, manufacturing,
developing, selling or marketing of Products and shall, and shall cause each Loan Party to, maintain and comply in all material
respects with all such Regulatory Required Permits, the noncompliance with which could have a Material Adverse Effect.

 

Section 6.13         Accounts

 

Borrower shall cause
all of its Deposit Accounts in Canada to be held with the Lender within 90 days of the Closing Date, provided that, for certainty,
all banking services offered to the Borrower will be subject to fees comparable with customers similar to the Borrower and in accordance
with the Lender’s standard practice in effect from time to time.

 

Section 6.14         Negative
Covenants.

 

Without the prior written
consent of Lender, no Loan Party shall (or shall permit any of its Subsidiaries, if any, to):

 

		(a)	incur, issue or make any request for or permit to
exist Indebtedness, except for the Permitted Indebtedness;

 

		(b)	grant or permit the existence of any Lien other than
Permitted Encumbrances, or enter into any agreement which prohibits the granting of any Lien or assignment by way of security
in the assets of any Loan Party or any Subsidiary (including a Lien in such instrument, contract, document or agreement);

 

		(c)	make any Disposition of material Property (including
Intellectual Property) except for:

 

		(i)	Dispositions of obsolete or worn-out Equipment;

 

		(ii)	Dispositions that comply with Section 3.05(a);
and

 

		(iii)	Dispositions among Loan Parties;

 

    	 	- 46 -	 

     

    

 

		(d)	wind-up or liquidate any Loan Party unless the assets
thereof are transferred to another Loan Party and all documents reasonably requested by Lender are delivered in order to preserve
the Liens under the Security Documents;

 

		(e)	merge, amalgamate or enter into another form of business
combination or reorganization (including any joint venture or partnership), except that (i) any Loan Party may merge, amalgamation
or consolidated with any other Loan Party, and (ii) any Subsidiary may merge, amalgamate or consolidate into a Loan Party or another
Subsidiary, provided that such merger, amalgamation or consolidation does not result in assets being transferred from a Loan Party
to a Subsidiary that is not a Loan Party, in each case so long as all documents reasonably requested by the Lender are delivered
in order to preserve the Liens under the Security Documents,

 

		(f)	make any payment of any dividend, distribution, redemption
or other payment (either cash or non-cash) in respect of any Loan Party’s Equity Interests, other than Permitted Distributions;

 

		(g)	make any Investment other than Permitted Investments;

 

		(h)	make any Acquisition other than Permitted Acquisitions;

 

		(i)	change the jurisdiction of organization of any Loan
Party, or amend any Loan Party’s Governing Documents in a manner which could reasonably be expected to have a Material Adverse
Effect;

 

		(j)	engage in any business other than the business engaged
in as of the Closing Date or substantially any substantially similar line of business as Borrower or in an adjacent line of business;

 

		(k)	permit a Change of Control, except if Lender will
be paid in full in cash at the closing of such Change of Control in accordance with Section 3.05(c);

 

		(l)	make or incur any capital expenditures in any fiscal
year in the aggregate in an amount which exceeds the amount set forth in the Budget for such a period by more than 15%; and

 

		(m)	agree or otherwise commit to take any action described
in paragraphs (a) through (l) above.

 

Section 6.15         Maintenance
of Records.

 

The Loan Parties will keep and maintain accurate and
complete records of the Collateral.

 

    	 	- 47 -	 

     

    

 

Section 6.16         Notices.

 

Borrower shall provide written notice to Lender at
least 30 days prior to:

 

		(a)	any change in legal name, or jurisdiction of organization,
or chief executive office of any Loan Party, or commencing operations in a new province in Canada; or

 

		(b)	any amendment to the Governing Documents of any Loan
Party; and

 

Promptly upon becoming aware of same, Borrower shall
provide prompt written notice to Lender, of:

 

		(a)	any Lien (other than Permitted Encumbrances) on, or
claim asserted against, any of the Collateral;

 

		(b)	the occurrence of any event, claim or occurrence that
is or could reasonably be expected to have a Material Adverse Effect, including without limitation, any notice of default pursuant
to any license, Permit or other agreement pursuant to which a Loan Party or any of its Subsidiaries licenses, Material Intellectual
Property or the commencement of any litigation;

 

		(c)	any change in the location of material Collateral
(including additional locations);

 

		(d)	any material loss of or damage to any of the Collateral;

 

		(e)	any material communication with or notice from the
TSX; and

 

		(f)	any Material Adverse Change.

 

Section 6.17         Limitations
on Modifications, Waivers, Extensions.

 

Other than in the ordinary
course of business, no Loan Party will (or will permit any of its Subsidiaries, if any, to): (i) amend, modify, terminate or waive
any provision of any Permit, contract, license or any agreement giving rise to a material Account except in the ordinary course
of business and which would not result in a Material Adverse Effect; or (ii) fail to exercise promptly and diligently its rights
under each Permit, contract and agreement giving rise to an Account except in the ordinary course of business and if such failure
is or could not reasonably be expected to have a Material Adverse Effect.

 

Section 6.18         Financial
Covenant

 

The Loan Parties shall
ensure that Unrestricted Cash at all times is greater than aggregate Operating Cash Expenditures during any given trailing three
(3) month period, to be tested as of the last day of each month based on the most recently reported consolidated financial statements
delivered pursuant to Section 6.11(a) of this Agreement and reported on in the most recent Compliance Certificate.

 

    	 	- 48 -	 

     

    

 

Section 6.19         Intellectual
Property.

 

		(a)	Each of the Loan Parties shall protect, defend and
maintain the validity and enforceability of the Material Intellectual Property and shall not allow any Material Intellectual Property
to be abandoned, forfeited or dedicated to the public without Lender’s consent. No Subsidiary that is not a Loan Party shall
own any Material Intellectual Property.

 

		(b)	No Loan Party shall, or shall permit any of its Subsidiaries
to, enter into a license with respect to Material Intellectual Property with respect to which any Loan Party or such Subsidiary
is the licensee that prohibits or otherwise restricts a Loan Party or any Subsidiary from granting a security interest in a Loan
Party’s or any Subsidiary’s interest in such license or agreement or would adversely affect Lender’s ability
to exercise remedies pursuant to any Financing Documents with respect to Collateral without prior notice to Lender and obtaining
such modifications to such license or agreement to ensure Lender’s rights and remedies pursuant to the Financing Documents
are not materially impaired as Lender may request. The Loan Parties shall not be in material breach of any licenses and agreements
pursuant to which any Loan Party licenses Material Intellectual Property.

 

		(c)	Together with each Compliance Certificate for the
months ending March, June, September and December, Borrower shall provide Lender with a report of patents, patent applications,
copyright registrations, copyright applications, trademark registrations and trademark applications acquired by any Loan Party
or any of its Subsidiaries since the last such report delivered including a report regarding any new in-bound licenses or sublicense
agreements pertaining to Material Intellectual Property or new material out-bound license or sublicense agreements to which a
Loan Party is a party (in each case except for licenses of commercially available software or information technology services),
together with all copies of such applications, licenses, agreements or registrations as Lender may request. With respect to any
Intellectual Property registered in Canada, the United States or any other applicable jurisdiction and acquired by any Loan Party
or changed after the Closing Date, each of the Loan Parties hereby agrees to give notice of same to the Lender and upon Lender’s
request, to deliver, or cause any other Guarantor to deliver, to Lender an Intellectual Property Security Agreements or other
documents as Lender may reasonably require to perfect its Lien therein or protect its interest with respect thereto, and authorizes
Lender to amend any previously delivered Intellectual Property Security Agreement to amend any schedule thereto to reflect such
addition or change. Borrower shall promptly notify Lender of the institution of any action, suit, litigation or proceeding pertaining
to the Material Intellectual Property of any Loan Party or a claim of infringement by any Loan Party or any of its Subsidiaries
on the intellectual property rights of a third party.

 

    	 	- 49 -	 

     

    

 

Section 6.20         Pension
Plans

 

The Loan Parties shall
fund and maintain all Pension Plans and Welfare Plans, if any, in compliance with all Laws.

 

Section 6.21         Material
Subsidiaries

 

The Loan Parties shall
cause each Material Subsidiary to promptly comply with Section 4.03. The Loan Parties shall ensure that all Material Agreements
are entered into by and all Material Intellectual Property is held through entities that are Loan Parties.

 

Section 6.22         Centre
of Main Interests

 

Each Loan Party incorporated
in a member state of the European Union must not cause or allow its registered office or Centre of Main Interests to be in, or
maintain an Establishment in, any jurisdiction other than its jurisdiction of incorporation.

 

Section 6.23         Post-Closing
Obligations

 

The Loan Parties shall satisfy the following
obligations after the Closing Date:

 

		(a)	within 10 Business Days after the Closing Date, the
Loan Parties shall deliver the German Security Agreements together with all customary officer’s certificates, resolutions
and opinions required by the Lender related to PM Germany and such Financing Documents to which it will have become a party and
the Borrower’s pledge of PM Germany (including, for the avoidance of doubt, legal opinions from Borrower’s and Lender’s
counsel in Germany), in each case in form and substance satisfactory to Lender;

 

		(b)	within 20 Business Days after the Closing Date, the
Borrower as sole shareholder of PM Germany shall take all required action to amend the articles of association (Satzung)
of PM Germany with the effect that the creation of pledges over, and the transfer of, shares in PM Germany are not subject to
any restriction of any kind (in particular to procure that paragraph 6 of the articles of association of PM Germany is deleted),
and promptly provide evidence thereof to Lender; and

 

		(c)	when available after the Closing Date, but in no event
later than 30 days thereafter, the Loan Parties shall deliver formal evidence of the repayment and termination of the unsecured
Investment in Business Innovation Business Start-ups Contribution Agreement dated December 16, 2011 among Her Majesty the Queen
in Right of Canada and Profound Medical Inc.

 

    	 	- 50 -	 

     

    

 

ARTICLE VII.

CONDITIONS

 

Section 7.01         Conditions
Precedent to the Initial Extension of Credit.

 

The obligations of
Lender on the Closing Date, are subject to the fulfillment, to the satisfaction of Lender, of each of the conditions precedent
set forth below (unless provided on such later date stated in Section 6.23:

 

		(a)	Lender shall have received this Agreement and each
of the other Financing Documents, in form and substance satisfactory to Lender, duly executed by each Person party thereto, and
each such document shall be in full force and effect, and no Default or Event of Default shall exist as of the execution of such
documents;

 

		(b)	Lender shall have received confirmation that the Security
Documents (to the extent applicable) have been registered in the applicable jurisdictions so as to result in perfected of security
in all jurisdictions required by the Lender on the Closing Date;

 

		(c)	Lender shall have received the Warrants on the terms
described in the Term Sheet;

 

		(d)	Lender shall have received the applicable fees outlined
in Section 2.03(b) together with any other fees contemplated by this Agreement and payable on the Closing Date;

 

		(e)	Lender shall have received a payoff letter with respect
to the Existing Loan Facility together with all documents as Lender may reasonably require in connection with the payoff of the
Existing Loan Facility to evidence the payoff and release of all Liens pursuant to the Existing Loan Facility;

 

		(f)	Lender shall have received Collateral Access Agreements
for the Borrower’s Mississauga, Ontario location;

 

		(g)	Lender shall have received a certificate from an officer
of each Loan Party attesting to (i) the resolutions of such Loan Party’s applicable Board authorizing its execution, delivery,
and performance of this Agreement and the other Financing Documents to which it is a party, (ii) the resolutions of such Loan
Party’s stockholders, shareholders or members, as applicable, to the extent required pursuant to such Loan Party’s
Governing Documents, (iii) such Loan Party’s Governing Documents, certified by the applicable jurisdiction of organization,
and (iv) to the extent applicable in the relevant jurisdiction of incorporation, incumbency of the officers of such Loan Party;

 

		(h)	to the extent applicable in the relevant jurisdiction
of incorporation, Lender shall have received a certificate of existence or good standing (or equivalent) with respect to each
Loan Party, dated within 10 days of the Closing Date, which certificate shall indicate the good standing in the applicable jurisdiction
of organization;

 

    	 	- 51 -	 

     

    

 

		(i)	Lender shall have received the Budget, together with
such financial statements as Lender may require;

 

		(j)	Lender shall have received a legal opinion letter
of (i) Borrower’s counsel in Canada and the United States of America;

 

		(k)	Each of the Loan Parties shall have received all licenses,
approvals, consents or evidence of other actions required by any Person in connection with the execution and delivery by such
Loan Party of this Agreement or any other Financing Document or with the consummation of the transactions contemplated hereby
and thereby;

 

		(l)	Lender shall have received one or more certificates
of insurance, together with the endorsements thereto, as are required by Section 6.08, the form and substance of which
shall be satisfactory to Lender;

 

		(m)	No action, suit, investigation, litigation or proceeding
before any arbitrator or Tribunal that could reasonably be expected to have a Material Adverse Effect if adversely determined
shall be pending or threatened against any Loan Party or any Subsidiary;

 

		(n)	Lender shall have completed its business, legal, and
Collateral due diligence, the results of which shall be satisfactory to Lender in its sole discretion;

 

		(o)	No Material Adverse Effect shall have occurred;

 

		(p)	The Borrower’s Deposit Account and operating
Account with the Lender shall have been opened;

 

		(q)	No Material Adverse Change shall have occurred since
the date of the Term Sheet.

 

		(r)	The Loan Parties shall have paid all Lender Expenses
incurred in connection with the transactions evidenced by this Agreement; and

 

		(s)	All other documents and legal matters in connection
with the transactions contemplated by this Agreement shall have been delivered, executed, or recorded and shall be in form and
substance satisfactory to Lender.

 

    	 	- 52 -	 

     

    

 

Section 7.02         Conditions
Precedent to all Extensions of Credit.

 

The obligation of Lender to make any Loans
or other credit extensions under this Agreement shall be subject to the following conditions precedent:

 

		(a)	the representations and warranties contained in this
Agreement and the other Financing Documents shall be true and correct in all material respects on and as of the date of such extension
of credit, as though made on and as of such date (except to the extent that such representations and warranties relate solely
to an earlier date);

 

		(b)	(i) no Default or Event of Default shall have occurred
and be continuing on the date of such extension of credit, nor shall either result from the making thereof, (ii) no Material Adverse
Effect shall have occurred, and (iii) there has been no material deterioration in the consolidated financial condition of the
Loan Parties since the date of the most recent financial statements submitted to Lender;

 

		(c)	as a condition to the Tranche B Term Loan, (i) Borrower
shall have delivered the Tranche B Term Loan Request, (ii) Borrower shall have satisfied each of the Tranche B Conditions, and
(iii) Lender shall have received the Tranche B Commitment Fee and the Tranche B Closing Fee;

 

		(d)	no injunction, writ, restraining order, or other order
of any nature prohibiting, directly or indirectly, the extending of such credit shall have been issued and remain in force by
any Tribunal against any Loan Party, Lender, or any of their Affiliates; and

 

		(e)	in the case of the initial draw under the Tranche
B Term Loans only, the Lender shall have received additional Warrants on the terms described in the Term Sheet.

 

ARTICLE VIII.

EVENTS OF DEFAULT

 

Section 8.01         Events
of Default.

 

Any of the following shall constitute
an Event of Default under this Agreement:

 

		(a)	failure by any Loan Party to pay in cash all or any
part of the Secured Obligations (including, without limitation, principal and interest payments due hereunder) when due and payable
hereunder, and in the case of any amount other than principal (which shall not be subject to a cure period) such default shall
remain unremedied for a period of 2 Business Days after the due date;

 

		(b)	Any Loan Party ceases or threatens to cease to carry
on business in the ordinary course or any material part of its business;

 

		(c)	Any Loan Party or any Subsidiary becomes unable to
satisfy its liabilities as they become due, or at any time the realizable value of the Loan Parties’ assets is less than
the aggregate sum of its liabilities, or any of them otherwise commit an act of bankruptcy or admits that it is “insolvent;”

 

    	 	- 53 -	 

     

    

 

		(d)	Any Loan Party or any Subsidiary, any creditor of
such a party, or any other Person institutes any proceeding or takes any action or executes any agreement in connection with the
commencement of any proceeding:

 

		(i)	seeking to adjudicate any Loan Party or any Subsidiary
bankrupt or insolvent;

 

		(ii)	seeking liquidation, dissolution, winding-up, reorganization,
arrangement, protection, relief or composition of any Loan Party or Subsidiary or any material part of its property or debt, or
making a proposal with respect to any Loan Party or Subsidiary under any law relating to bankruptcy, insolvency, reorganization
or compromise of debts or other similar laws including, without limitation, all Insolvency Legislation, unless any such proceeding
or other action is successfully contested by the applicable Loan Party or Subsidiary in good faith and is dismissed or stayed
within 45 days;

 

		(iii)	seeking appointment of a receiver, receiver and manager,
trustee, agent, custodian, monitor, liquidator or similar official for any Loan Party or Subsidiary or for any part of their properties
and assets or for any part of the Collateral; or

 

		(iv)	takes any other action or steps to institute an Insolvency
Proceeding;

 

		(e)	a receiver, conservator, trustee, custodian, monitor,
liquidator or similar official is appointed in respect of any Loan Party or Subsidiary or any of the Collateral;

 

		(f)	a failure by any Loan Party or Subsidiary to make
payments of principal, interest or other amounts when due with respect to any other Indebtedness, or the occurrence of any default,
or any event or condition which, with the giving of notice or passage of time, or both, would constitute a default or event of
default by any Loan Party or Subsidiary under the terms of any Indebtedness in excess of Two Hundred and Fifty Thousand ($250,000);

 

		(g)	if any representation or warranty made by any Loan
Party in any of the Financing Documents or any other document, instrument or agreement executed and delivered by any Loan Party
at any time to or in favor of Lender is untrue or incorrect in any material respect as of the date on which it is made;

 

		(h)	any Loan Party breaches or fails to duly perform or
observe any covenant contained in Section 6.14 or Section 6.23;

 

    	 	- 54 -	 

     

    

 

		(i)	any Loan Party fails to observe the covenants set
forth in Article VI (other than those contained in Section 6.14 and Section 6.23) of this Agreement or any other
term, covenant or agreement contained herein or in any of the Financing Documents or any other document, instrument or agreement
executed and delivered by any Loan Party at any time to or in favor of Lender and such failure is not cured to the satisfaction
of the Lender, acting reasonably, within 10 Business Days after the earlier of (i) written notice thereof by the Lender to the
Borrower and (ii) actual knowledge of the Borrower of the same;

 

		(j)	any Loan Party challenges or threatens to challenge
the validity or enforceability of any of the Financing Documents or terminates or repudiates any of them or attempts to do so,
or such Financing Documents or any other document, instrument, agreement or certificate executed and delivered by any Loan Party
to Lender shall cease to be in full force and effect or fail, in whole or in part, to constitute a legal, valid, binding and enforceable
obligation of any Loan Party, as the case may be;

 

		(k)	any Security Document shall cease to create a valid
Lien in favor of Lender or Lender’s Lien ceases to be a perfected, first priority Lien in the Collateral (subject to Permitted
Encumbrances), or any occurrence, development or change shall occur, which has resulted or is reasonably expected to result in
impairment in the perfection or priority of the Liens granted to Lender other than pursuant to Permitted Encumbrances, or there
is a material impairment of the Collateral;

 

		(l)	any part of the Collateral is attached, seized, levied
on or becomes subject to any similar process, or any Governmental Authority (including an administrative body or taxation authority)
issues a demand in respect of any Loan Party on any part of the Collateral, or any creditor enforces a Lien on the Collateral
or otherwise takes possession of property of any Loan Party, or gives written notice of its intent to do any of the foregoing
(unless such notice contested in good faith by appropriate legal proceedings and appropriate reserves satisfactory to Lender have
been taken);

 

		(m)	any resolution is passed for the winding up, dissolution
or liquidation or amalgamation of any Loan Party other than as permitted by Section 6.14(d) or Section 6.14(e) or
if any Loan Party loses its charter by expiration, cancellation, forfeiture or otherwise;

 

		(n)	there is entered into against any Loan Party or Subsidiary
a judgment or order for the payment of money in an aggregate amount in excess of $250,000 or for equitable relief to enjoin, restrain
or prevent any Loan Party or Subsidiary from conducting any material part of its business, or which would otherwise reasonably
be expected to have a Material Adverse Effect;

 

		(o)	a Change of Control occurs;

 

		(p)	any Permit (including any Regulatory Required Permit)
shall have been revoked, rescinded, suspended, modified in an adverse manner or not renewed for a full term, and such revocation,
rescission, suspension, modification or non-renewal has, or could reasonably be expected to have, a Material Adverse Effect.;

 

    	 	- 55 -	 

     

    

 

		(q)	a Pension Plan Event occurs;

 

		(r)	if the common shares of the Parent cease to be listed
for trading on the TSX, the Parent ceases to be a reporting issuer in good standing in the Province of Ontario, a cease trade
order is issued by a Governmental Authority with respect to the common shares of the Parent which order is in effect for more
than twenty (20) Business Days or if the Parent appears on the list of defaulting issuers maintained by the Ontario Securities
Commission available for consultation on its website;

 

		(s)	the occurrence of a Material Adverse Change; or

 

		(t)	any other event or circumstance occurs that could
reasonably give rise to a Material Adverse Effect.

 

Section 8.02         Lender’s
Remedies Upon Default.

 

		(a)	Upon the occurrence, and during the continuation,
of an Event of Default, Lender may exercise any of the rights and remedies of a secured party under the PPSA or other similar
applicable foreign Law, and any other rights and remedies provided for in this Agreement or any other Financing Document or otherwise
available to it at law or in equity, such rights and remedies to include, without limitation, the following, all of which are
authorized by each Loan Party:

 

		(i)	Declare all Secured Obligations, whether evidenced
by this Agreement, by any of the other Financing Documents, or otherwise, immediately due and payable;

 

		(ii)	Cease advancing money or extending credit to or for
the benefit of Borrower under this Agreement, under any of the Financing Documents, or under any other agreement between any Loan
Party, and Lender;

 

		(iii)	Terminate this Agreement and any of the other Financing
Documents as to any future liability or obligation of Lender, but without affecting any of Lender’s Liens in the Collateral
and without affecting the Secured Obligations;

 

		(iv)	Settle or adjust disputes and claims directly with
Account Debtors for amounts and upon terms which Lender in its sole discretion considers advisable, and in such cases, Lender
will credit Borrower’s Loan Account with only the net amounts received by Lender in payment of such Accounts after deducting
all Lender Expenses incurred or expended in connection therewith;

 

		(v)	Without notice to any Loan Party (such notice being
expressly waived), and without constituting a retention of any collateral in satisfaction of an obligation (within the meaning
of the PPSA or other similar applicable foreign Law), set off and apply to the Secured Obligations any and all (i) funds coming
into possession of Lender, or (ii) Indebtedness at any time owing to or for the credit or the account of any Loan Party held by
Lender;

 

    	 	- 56 -	 

     

    

 

		(vi)	Deliver a notice of exclusive control, any entitlement
order, or other directions or instructions pursuant to any Control Agreement or similar agreements providing control of any Collateral;

 

		(vii)	take any and all other remedies at Law or provided
for under the applicable Security Documents.

 

Section 8.03         Lender
Protective Payments.

 

Without notice to or
demand upon any Loan Party, make such payments and do such acts as Lender considers necessary or reasonable to protect its security
interests in the Collateral, enhance the likelihood of repayment of the Secured Obligations, or pay any other amount payable by
or chargeable to any Loan Party pursuant to the terms of this Agreement, including costs, fees, and expenses, and Lender Expenses.
All such amounts shall be added to the principal of the Term Loan outstanding hereunder, and be repayable on demand and secured
by the Collateral.

 

Section 8.04         Remedies
Cumulative.

 

The rights and remedies
of Lender under this Agreement, the other Financing Documents, and all other agreements shall be cumulative. Lender shall have
all other rights and remedies not inconsistent herewith as provided under the PPSA or other similar applicable foreign Law, by
law, or in equity. No exercise by Lender of one right or remedy shall be deemed an election, and no waiver by Lender of any Event
of Default shall be deemed a continuing waiver. No delay by Lender shall constitute a waiver, election, or acquiescence by it.

 

Section 8.05         Power
of Attorney.

 

Each Loan Party hereby
irrevocably makes, constitutes, and appoints Lender (and any of Lender’s officers, employees, or agents designated by Lender)
as such Loan Party’s true and lawful attorney, during the existence of an Event of Default, with power to (a) sign the name
of such Loan Party on any Additional Documents, (b) sign such Loan Party’s name on any invoice or bill of lading relating
to the Collateral, drafts against Account Debtors, or notices to Account Debtors, (c) send requests for verification of Accounts,
(d) endorse such Loan Party’s name on any collection item that may come into Lender’s possession, (e) make, settle,
and adjust all claims under such Loan Party’s policies of insurance and make all determinations and decisions with respect
to such policies of insurance, and (f) pay, contest or settle any Lien or other encumbrance or adverse claim in or to the Collateral
or any judgment based thereon. The appointment of Lender as each such Loan Party’s attorney, and each and every one of its
rights and powers, being coupled with an interest, is irrevocable until all of the Secured Obligations have been fully and finally
repaid and performed and any obligation of Lender to extend credit hereunder is terminated.

 

    	 	- 57 -	 

     

    

 

Each Loan Party hereby
releases Lender (and any of Lender’s officers, employees, or agents designated by Lender) from the restrictions (to the extent
that such restrictions would otherwise apply) on self-dealing and multi-representation pursuant to section 181 of the German Civil
Code (Bürgerliches Gesetzbuch) and similar restrictions (if any) applicable to it pursuant to any other applicable
laws, in each case to the extent legally possible to such Loan Party. For the avoidance of doubt, if and to the extent that Lender
is authorised to sub-delegate (by power of attorney or otherwise) any powers granted to it under the Financing Documents (or any
of them), this shall extend to include such release. Each Loan Party which is barred by its constitutional documents, by-laws or
otherwise from validly granting such release will inform Lender accordingly.

 

Section 8.06         Notice
of Event of Default.

 

Each Loan Party shall
promptly give notice in writing to Lender of the occurrence of any Event of Default or other event which, with the lapse of time
or giving of notice or otherwise, would be an Event of Default, forthwith upon becoming aware thereof. Such written notice shall
specify the nature of such default or Event of Default and the steps taken to remedy the same.

 

Section 8.07         Default
under Other Encumbrances.

 

Any amount paid by
Lender before or after the occurrence of an Event of Default on account of monies payable under any Lien upon the Collateral or
any part thereof shall be repaid by the Loan Parties to Lender on demand and shall:

 

		(a)	be added to the Secured Obligations and constitute
a charge upon the Collateral; and

 

		(b)	bear interest at the rate equal to the Post-Default
Rate as a reasonable and genuine pre-estimate of damages and not as a penalty.

 

Section 8.08         Judgment.

 

Neither the taking
of any judgment nor the exercise of any power of seizure or sale shall operate to extinguish the liability of the Loan Parties
to perform the Secured Obligations nor shall such operate as a merger of any covenant or affect the right of Lender to receive
interest at the specified rate, and any judgment shall bear interest at such rate.

 

Section 8.09         Application
of Proceeds.

 

During the existence
of an Event of Default, Lender may apply in any order all payments received or funds coming into its possession.

 

    	 	- 58 -	 

     

    

 

Section 8.10         Limitation
of Liability.

 

Lender shall not be
liable by reason of any entry into or taking possession of any of the Collateral charged or intended to be charged by the Security
Documents or any part thereof, to account as mortgagee in possession or for anything except actual receipts or be liable for any
loss on realization or any act or omission for which a secured party in possession might be liable. Lender shall not, by virtue
of these presents, be deemed to be a mortgagee in possession of the Collateral. Lender shall not be liable or accountable for any
failure to exercise its remedies, take possession of, seize, collect, realize, sell, lease or otherwise dispose of or obtain payment
for the Collateral and shall not be bound to institute proceedings for such purposes or for the purpose of preserving any rights,
remedies or powers of Lender, any Loan Party or any other person in respect of same. Each Loan Party hereby releases and discharges
Lender from every claim of every nature, whether sounding in damages or not, which may arise or be caused to any Loan Party or
any person claiming through any Loan Party by reason or as a result of anything done or omitted to be done, as the case may be,
by Lender or any successor or assign claiming through or under Lender under the provisions of this Agreement, unless such claim
is the result of Lender’s gross negligence or willful misconduct as determined by a final, non-appealable judgment. The guarantee
limitations set forth in clause 4.10 of the Canadian Guarantee shall apply mutatis mutandis to any indemnity granted by
or other secondary liability of a Loan Party incorporated as limited liability company (GmbH) in Germany to the Lender pursuant
to this Section 8.10.

 

Section 8.11         Borrower
Liable

 

Borrower hereby waives
any requirement that the Lender protect, secure, perfect or insure any security interest or Lien, or any property subject thereto,
or exhaust any right or take any action against any other Loan Party or other entity. Borrower agrees not to seek payment directly
or indirectly from another Loan Party through a claim of indemnity, contribution, or otherwise with respect to the Secured Obligations,
until the Secured Obligations have been repaid in full and this Agreement has terminated. Any agreement providing for indemnification,
reimbursement or any other arrangement prohibited under this Section shall be null and void. If any payment is made to a Loan Party
in contravention of this Section, such Loan Party to hold such payment in trust for Lender and such payment shall be promptly delivered
to Lender for application to the Secured Obligations, whether matured or unmatured.

 

ARTICLE IX.

GENERAL

 

Section 9.01         Releases.

 

Lender may in its discretion
from time to time release any part of the Collateral or any other security either with or without any sufficient consideration
therefor, without responsibility therefor and without thereby releasing any other part of the Collateral or any other security
or any Person from the security created by this Agreement or any of the Financing Documents or from any of the covenants herein
contained. Each and every portion into which the Collateral is or may hereafter be divided does and shall stay subject to the Lien
pursuant to this Agreement. No Person shall have the right to require the Secured Obligations to be apportioned and Lender shall
not be accountable to any Loan Party for any moneys except those actually received by Lender.

 

    	 	- 59 -	 

     

    

 

Section 9.02         Governing
Law; Jurisdiction; Jury Trial Waiver and Judicial Reference.

 

All Financing Documents,
except if expressly provided otherwise therein, shall be exclusively (without regard to any rules or principles relating to conflicts
of laws) governed by, enforced and construed in accordance with the laws of the Province of Ontario and the federal laws of Canada
applicable therein. Each Loan Party hereby irrevocably and unconditionally consents, for itself and its property, to the exclusive
jurisdiction of the courts of the Province of Ontario with respect to any matter arising under or relating to this Agreement or
any of the other Financing Documents, except if expressly provided otherwise therein. Each Loan Party expressly submits and consents
in advance to such jurisdiction in any action or suit commenced in any such court, and such Loan Party hereby waives any objection
that it may have based upon lack of personal jurisdiction, improper venue, or forum non conveniens and hereby consents to the granting
of such legal or equitable relief as is deemed appropriate by such court. Nothing in this Agreement shall affect any right that
Lender may otherwise have to bring any action or proceeding relating to any Financing Document against a Loan Party or its properties
in the courts of any jurisdiction. Each Loan Party hereby waives personal service of the summons, complaints and other process
issued in such action or suit and agrees that service of such summons, complains and other process may be made by registered or
certified mail addressed to Borrower as its duly appointed process agent at the address set forth in, or subsequently provided
to Lender in accordance with this Agreement, and that service so made shall be deemed completed upon the earlier to occur of Borrower’s
actual receipt thereof or three (3) days after deposit in the U.S. mails, proper postage paid. TO THE FULLEST EXTENT PERMITTED
BY APPLICABLE LAW, EACH LOAN PARTY AND LENDER WAIVES THEIR RIGHT TO A JURY TRIAL OF ANY CLAIMS OR CAUSE OF ACTION ARISING OUT OF
OR BASED UPON THIS AGREEMENT, THE FINANCING DOCUMENTS OR ANY CONTEMPLATED TRANSACTION, INCLUDING CONTRACT, TORT, BREACH OF DUTY
AND ALL OTHER CLAIMS. THIS WAIVER IS A MATERIAL INDUCEMENT FOR BOTH PARTIES TO ENTER INTO THIS AGREEMENT. EACH PARTY HAS REVIEWED
THIS WAIVER WITH ITS COUNSEL.

 

Section 9.03         Whole
Agreement.

 

This Agreement and
other Financing Documents and any and all other documents ancillary thereto and executed and delivered in connection therewith,
constitute the entire agreement between the parties hereto with respect to the subject matter hereof.

 

Section 9.04         Time.

 

Time shall be of the
essence of all provisions of this Agreement and the other Financing Documents.

 

Section 9.05         Notices.

 

Any notice or other
communication required or permitted to be given hereunder shall be in writing and shall be given by prepaid first-class mail, or
means of electronic communication or by hand-delivery as hereinafter provided. Any such notice or other communication, if mailed
by prepaid first-class mail at any time other than during, or within three (3) Business Days prior to, a general discontinuance
of postal service due to strike, lockout or otherwise, shall be deemed to have been received on the fourth Business Day after the
postmarked date thereof, or if sent or by means of electronic communication, shall be deemed to have been received on the Business
Day of the sending (provided it was sent before 4:30 p.m. Toronto, Ontario time), or if delivered by hand shall be deemed to have
been received at the time it is delivered to the applicable address noted below either to the individual designated below or to
an employee of the addressee at such address with responsibility for matters to which the information relates. Notice of change
of address shall also be governed by this Section 9.05. In the event of a general discontinuance of postal service due to
strike, lock-out or otherwise, notices or other communications shall be delivered by hand or any means of electronic communication
and shall be deemed to have been received in accordance with the foregoing. Notices and other communications shall be addressed
as follows:

 

    	 	- 60 -	 

     

    

 

		(a)	if to the Loan Parties:

 

Profound Medical Inc.

2400 Skymark Ave. Unit #6

Mississauga, Ontario

 

Attention: Aaron Davidson, Chief Financial Officer
and Senior VP Corporate Development

Email: ADavidson@profoundmedical.com

 

with a copy (that does not constitute notice) to:

 

Torys LLP

79 Wellington St W #3000

Toronto, ON M5K 1N2

 

Attention: Amanda Balasubramanian

Email: abalasubramanian@torys.com

 

		(b)	if to Lender:

 

for any borrowing request:

 

Canadian Imperial Bank of Commerce

Credit Processing Services

595 Bay Street, 5th
floor

Toronto, Ontario

M5H 2C2

e-mail: gregory.mcdonald@cibc.com

 

Attention: Gregory McDonald

 

    	 	- 61 -	 

     

    

 

for all other notices:

 

CIBC Innovation Banking

40 King S. West, Suite 5702

Toronto, Ontario

M5H 3Y2

facsimile: 416-682-1160

e-mail: jeff.chapman@cibc.com

 

Attention:         Jeff Chapman

 

with a copy (that does not constitute notice) to:

 

Goodmans LLP

333 Bay Street, Suite 3400

Toronto, Ontario M5H 2S7

Facsimile: 416-979-1234

e-mail: mbertrand@goodmans.ca

 

Attention:         Michael Bertrand

 

Section 9.06         Successors
and Assigns.

 

This Agreement shall
be binding on each Loan Party and its successors and assigns and shall inure to the benefit of Lender and its successors and permitted
assigns. Each Loan Party agrees not assign, transfer or delegate any of its rights or obligations under this Agreement without
the prior written consent of Lender which it may exercise in its sole and absolute discretion. Lender shall be entitled to assign
this Agreement to any other party (with, so long as no Default or Event of Default has occurred, the consent of Borrower); provided,
that so long as no Default or Event has occurred, such assignment shall not increase the relevant Loan Party’s obligation
to reimburse, indemnify or make whole the Lender pursuant to Section 3.09  or Section 3.10 as a result of such assignment.
Notwithstanding the foregoing, an assignment to an Affiliate of Lender may be made at any time without consent.

 

Section 9.07         Indemnification.

 

Each Loan Party hereby
agrees to indemnify, defend and hold Lender and its principals, employees, agents, attorneys, or any other Person affiliated with
or representing Lender (each, an “Indemnified Person”) harmless against: (i) all obligations, demands, claims,
and liabilities (collectively, “Indemnified Claims”) claimed or asserted by any other party in connection with
the transactions contemplated by the Financing Documents; and (ii) all losses or expenses (including Lender Expenses) in any way
suffered, incurred, or paid by such Indemnified Person as a result of, following from, consequential to, or arising from transactions
between Lender and any Loan Party (including attorneys’ and other legal fees and expenses), except for Indemnified Claims
or losses finally determined by a court of competent jurisdiction to have been directly caused by such Indemnified Person’s
gross negligence or willful misconduct. This provision shall survive the termination of this Agreement and the repayment of the
Secured Obligations. The guarantee limitations set forth in clause 4.10 of the Canadian Guarantee shall apply mutatis mutandis
to any indemnity granted by or other secondary liability of a Loan Party incorporated as limited liability company (GmbH)
in Germany to the Lender pursuant to this Section 9.07.

 

    	 	- 62 -	 

     

    

 

Section 9.08         No
Set-Off.

 

The Secured Obligations
shall be paid by the Loan Parties without regard to any set-off, withholding, counterclaim or equities between any Loan Party and
Lender.

 

Section 9.09         Permitted
Encumbrance.

 

Notwithstanding any
other provision in this Agreement, the parties confirm their intent that the references to Permitted Encumbrances herein are not
intended to imply the subordination by Lender to any Person whatsoever.

 

Section 9.10         Press
Releases.

 

Each Loan Party agrees
that Lender may issue press releases announcing the fact and extension of the financing under this Agreement and further agrees
that Lender may display any Loan Party’s logo on its website and collateral material consistent with its other portfolio
companies. Lender’s use of such logo shall be subject to such Loan Party’s approval, which shall not be unreasonably
withheld.

 

Section 9.11         Confidentiality.

 

Lender agrees to use
the same degree of care that it exercises with respect to its own proprietary information to maintain the confidentiality of any
and all proprietary, trade secret or confidential information provided to or received by Lender from or on behalf of the Loan Parties,
which indicates that it is confidential or would reasonably be understood to be confidential, including business plans and forecasts,
non-public financial information, confidential or secret processes, formulae, devices and contractual information, customer lists,
and employee relation matters, provided that Lender may disclose such information to its officers, directors, employees, attorneys,
accountants and affiliates, and such other Persons to whom Lender shall at any time be required to make such disclosure in accordance
with Applicable Law and in connection with the exercise of remedies, and provided that the foregoing shall not apply to information
that is in the public domain or becomes part of the public domain (other than as a result of its disclosure by Lender in violation
of this Agreement) after disclosure to Lender. The confidentiality agreement in this Section supersedes any prior confidentiality
agreement of Lender relating to the Loan Parties.

 

Section 9.12         Judgment
Currency

 

		(a)	If for the purpose of obtaining or enforcing judgment
against any Loan Party in any court in any jurisdiction, it becomes necessary to convert into any other currency (such other currency
being hereinafter in this Section 9.12 referred to as the “Judgement Currency”) an amount due in into
another currency (referred to as the “Required Currency”), the conversion shall be made at the Exchange Rate
prevailing on the Business Day immediately preceding:

 

    	 	- 63 -	 

     

    

 

		(i)	the date of actual payment of the amount due, in the
case of any proceeding in the courts of the Province of Ontario or in the courts of any other jurisdiction that will give effect
to such conversion being made on such date; or

 

		(ii)	the date on which the judgment is given, in the case
of any proceeding in the courts of any other jurisdiction (the date as of which such conversion is made pursuant to this Section
9.12(a)(ii) being hereinafter in this Section referred to as the “Judgement Conversion Date”).

 

		(b)	If, in the case of any proceeding in the court of
any jurisdiction referred to in clause (a)(ii) of this section, there is a change in the rate of exchange prevailing between
the Judgement Conversion Date and the date of actual payment of the amount due, the Loan Parties, jointly and severally, shall
pay such additional or lesser amount as may be necessary to ensure that the amount paid in the Judgement Currency, when converted
at the rate of exchange prevailing on the date of payment, will produce the amount of the Required Currency, which could have
been purchased with the amount of Judgement Currency stipulated in the judgment or judicial order at the rate of exchange prevailing
on the Judgement Conversion Date.

 

		(c)	Any amount due from any Loan Party under the provisions
of Section (b) shall be due as a separate debt and shall not be affected by judgment being obtained for any other amounts due
under or in respect of this Agreement.

 

Section 9.13         Anti-Money
Laundering Legislation

 

		(a)	Each Loan Party acknowledges that, pursuant to the
Proceeds of Crime (Money Laundering) and Terrorist Financing Act (Canada) and other applicable anti-money laundering,
anti-terrorist financing, government sanction and “know your client” laws (collectively, including any guidelines
or orders thereunder, “AML Legislation”), Lender may be required to obtain, verify and record information regarding
the Loan Parties, their directors, authorized signing officers, direct or indirect shareholders or other Persons in control of
such Loan Party, and the transactions contemplated hereby. Each Loan Party shall promptly provide all such information, including
supporting documentation and other evidence, as may be reasonably requested by Lender, or any prospective assignee or participant
of Lender, in order to comply with any applicable AML Legislation, whether now or hereafter in existence.

 

		(b)	Each Loan Party acknowledges and agrees that pursuant
to the provisions of the USA Patriot Act (Title III of the Pub. L. 107-56) signed into law October 26, 2001 (the “Patriot
Act”), Lender may be required to obtain, verify and record information with respect to the Loan Parties, and each
Loan Party hereby agrees to cooperate with Lender and provide them with all information that may be required in order to fulfil
its obligations under the Patriot Act.

 

    	 	- 64 -	 

     

    

 

Section 9.14         Counterparts.

 

This Agreement may
be executed in several counterparts, each of which, when so executed, shall be deemed to be an original and which counterparts
taken together shall constitute one and the same Agreement. This Agreement may be executed by facsimile or pdf, and any signature
contained hereon by facsimile or pdf shall be deemed to be equivalent to an original signature for all purposes.

 

[REMAINDER OF PAGE INTENTIONALLY LEFT BLANK]

 

    	 	- 65 -	 

     

    

 

IN WITNESS WHEREOF, each of the parties hereto have duly executed
this Agreement as of date first written above.

 

	 	PROFOUND MEDICAL INC., as Borrower
	 	 	 
	 	Per:	/s/ Arun
    Menawat
	 	 	Name:	Arun Menawat
	 	 	Title:	Chief Executive Officer
	 	 	 	 
	 	Per:	/s/ Rashed
    Dewan
	 	 	Name:	Rashed Dewan
	 	 	Title:	VP Finance
	 	 	 	 
	 	PROFOUND MEDICAL CORP., as a
	 	Guarantor
	 	 	 	 
	 	Per:	/s/ Arun
Menawat
	 	 	Name:	Arun Menawat
	 	 	Title:	Chief Executive Officer
	 	 	 	 
	 	Per:	/s/ Aaron
    Davidson
	 	 	Name:	Aaron Davidson
	 	 	Title:	Chief Financial Officer
	 	 	 	 
	 	PROFOUND MEDICAL GMBH, as a
	 	Guarantor
	 	 	 	 
	 	Per:	/s/ Hartmut
Warnken
	 	 	Name:	Hartmut Warnken
	 	 	Title:	VP, Int. Sales
	 	 	 	 
	 	Per:	 
	 	 	Name:	 
	 	 	Title:	 

 

Signature Page – Credit Agreement

 

     

     

    

 

	 	PROFOUND MEDICAL (U.S.) INC., as a
	 	Guarantor
	 	 	 
	 	Per:	/s/ Arun
    Menawat
	 	 	Name:  	Arun Menawat
	 	 	Title:	President
	 	 	 	 
	 	Per:	/s/ Rashed
    Dewan
	 	 	Name:  	Rashed Dewan
	 	 	Title:	Secretary

 

    	 	- 2 -	 

     

    

 

	 	CANADIAN IMPERIAL BANK OF
	 	COMMERCE, as Lender
	 	 	 
	 	Per:	/s/ Mark
    Usher
	 	 	Name:  	Mark Usher
	 	 	Title:	Managing Director
	 	 	 	 
	 	Per:	 
	 	 	Name:	 
	 	 	Title:	 

 

Signature Page – Credit Agreement

 

     

     

    

 

Exhibit A

 

TRANCHE B TERM LOAN REQUEST

 

[                                              ,
20    ]

 

CIBC,

 

Ladies and Gentleman:

 

The undersigned, a Responsible Officer
of Profound Medical Inc., an Ontario corporation (“Borrower”), refer to the Credit Agreement, dated as of July
30, 2018 (as amended, restated, supplemented or otherwise modified from time to time, the “Credit Agreement”,
the terms defined therein being used herein as therein defined), among Borrower, the other Loan Parties party thereto and CIBC
(“Lender”), and hereby give you notice, irrevocably, pursuant to and as required by Section 2.02(b)(i)
of the Credit Agreement, that Borrower hereby requests a Tranche B Term Loan under the Credit Agreement, and confirms:

 

		1.	The requested date of the Tranche B Term Loan, which
is a Business Day, is [                ,
20      ].

 

		2.	The amount of the Tranche B Term Loan is $[l].

 

		3.	Each of the Tranche B Conditions have been met.

 

		4.	The Tranche B Closing Fee shall be [deducted from
the proceeds of the Loan] [has been paid separately as of the date hereof.]

 

		5.	The bank name, location and number of the account
to which funds are to be disbursed is attached.

 

The undersigned hereby represents and warrants
that, as of the date of this Tranche B Term Loan Request, the conditions set forth in Section 7.02 have been satisfied as
if such conditions were set forth herein.

 

[REMAINDER OF PAGE INTENTIONALLY LEFT BLANK]

 

     

     

    

 

[SIGNATURE PAGE TO TRANCHE B TERM LOAN REQUEST]

 

	 	Very yours truly,
	 	 
	 	[             ]
	 	 
	 	By:	 
	 	 	 
	 	Name:	 
	 	 	 
	 	Title:	 

 

     

     

    

 

Exhibit B

 

COMPLIANCE CERTIFICATE

 

                 
      , 201     

 

CIBC Innovation Banking

40 King S. West, Suite 5702

Toronto, Ontario

M5H 3Y2, Canada

 

Attention: Jeff Chapman

 

Re:Credit Agreement, dated as of July
30, 2018 (as amended, restated, supplemented or otherwise modified from time to time, the “Credit Agreement”),
among Profound Medical Inc., an Ontario corporation (the “Borrower”), the other Loan Parties from time to time
party thereto, and CIBC (“Lender”).

 

Ladies and Gentlemen:

 

Concurrently herewith
Borrower delivers to Lender the [monthly/quarterly/annual] financial statements for the period ending.
Any capitalized terms used herein but not defined shall have the meaning set forth in the Credit Agreement.

 

This letter shall serve
as certification by or on behalf of the Borrower to Lender of the following:

 

(a)          In
accordance with Section 6.10 of the Credit Agreement, (i) all financial statements delivered herewith have been prepared
in accordance with GAAP (except for the lack of footnotes and being subject to year-end audit adjustments) and fairly present in
all material respects the financial condition of the Loan Parties and each of its Subsidiaries at the close of, and results of
Borrower’s and each of its Subsidiaries’ operations and cash flows for, the periods covered, (ii) the Borrower has
properly made all statutory withholdings, (iii) the representations and warranties of the Loan Parties set forth in the Credit
Agreement are true and correct in all material respects as of the date hereof with the same force and effect as if such representations
and warranties had been made on and as of such time except for (A) such representations and warranties stated to be true as of
a specific date and (B) any changes to the schedules to such representations and warranties that arise in the ordinary course of
business and are not prohibited under the Credit Agreement and attached hereto, (iv) the Borrower has complied with all covenants,
conditions and other requirements contained in any Financing Document, (v) there has not occurred any Default or Event of Default,
and there has not occurred any breach or default under any other document, instrument or agreement (including any Material Agreement)
which would reasonably be expected to have a Material Adverse Effect and (vi) there has been no material deterioration in the consolidated
financial condition of the Loan Parties since the date of the most recent financial statements submitted to Lender.

 

     

     

    

 

(b)          In
accordance with Section 6.18 of the Credit Agreement, the Loan Parties are in compliance with the following financial covenants:

 

For the month ended                                           :

 

(A)         Unrestricted
Cash                                      $                                    

 

(B)         Trailing
3 Month Operating Cash            $                                    

Expenditures

 

Required: (A) must be greater than (B)

 

Complies:         ̈ Yes  ̈ No

 

(c)          Additional
confirmations:

 

		1.	Any change in the legal name, jurisdiction of organization
or location of chief executive office or registered office of any Loan Party or new Canadian Provinces in which they operate?

 

 ̈ Yes,
details listed below               ̈
No

 

		2.	Are there any new Deposit Accounts or Securities Accounts
opened by any Loan Party (not previously disclosed on a Compliance Certificate)?

 

 ̈ Yes,
details listed below               ̈
No

 

	Account 

Holder	 	Depository
/

Intermediary	 	Address	 	Account 

Number	 	Restricted	 	Control 

Agreement
	 	 	 	 	 	 	 	 	 ̈	 	 ̈

 

		3.	Have any Subsidiaries been formed, acquired other
than Subsidiaries set forth on Schedule 5.31 to the Agreement or as previously disclosed on a Compliance Certificate? Are
any of them Material Subsidiaries?

 

 ̈Yes,
details listed below, together with updated organizational chart

 

 ̈No

 

    	 	- 2 -	 

     

    

 

	Name	 	Jurisdiction of 

Organization	 	Shares 

Outstanding	 	Ownership of 

Subsidiary 

Shares 

(indicating 

percentage)	 	Purpose
	 	 	 	 	 	 	 	 	 
	 	 	 	 	 	 	 	 	 

 

(d)          Attached
hereto are any updates to the schedules to the Agreement to give effect to the statement in clause (a)(iii)(B) above.

 

(e)          [For
the certificate for March, June, September and December only to comply with the statement in Section 6.19(c) of the Credit Agreement]:
Attached is a list of new Intellectual Property acquired and not previously disclosed.

 

[REMAINDER OF PAGE INTENTIONALLY LEFT BLANK]

 

    	 	- 3 -	 

     

    

 

[SIGNATURE PAGE TO COMPLIANCE CERTIFICATE]

 

This Compliance Certificate is a Financing Document.
Such certification is made as of                     ,
201     .

 

	 	BORROWER:
	 	 
	 	[         ][[         ]]
	 	 
	 	By:	 
	 	 	 
	 	Name:	 
	 	 	 
	 	Title:	 

 

     

     

    

 

SCHEDULE OF EXCEPTIONS

 

[SCHEDULE OF EXCEPTIONS REDACTED]

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