Document:

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                                                                 EXHIBIT 10.5(b)

                              EMPLOYMENT AGREEMENT

         This Agreement made as of the 18th day of November, 1999, between
PerkinElmer, Inc., a Massachusetts corporation (hereinafter called the
"Company"), and Robert F. Friel, 16 Longmeadow Drive, Westwood, MA
02090(hereinafter referred to as the "Employee").

                                   WITNESSETH:

         WHEREAS, the Employee is being employed in a management position with
the Company; and

         WHEREAS, the Employee hereby agrees to continue to perform such
services and duties of a management nature as shall be assigned to him; and

         WHEREAS, the Employee hereby agrees to the compensation herein provided
and agrees to serve the Company to the best of his ability during the period of
this Agreement.

         NOW, THEREFORE, in consideration of the sum of One Dollar, and of the
mutual covenants herein contained, the parties agree as follows:

1.       a)       Except as hereinafter otherwise provided, the Company agrees
                  to employ the employee in a management position with the
                  Company, and the Employee agrees to remain in the employment
                  of the Company in that capacity for a period of one year from
                  the date hereof and from year to year thereafter until such
                  time as this Agreement is terminated.

         b)       The Company will, during each year of the term of this
                  Agreement, place in nomination before the Board of Directors
                  of the Company the name of the Employee for election as an
                  Officer of the Company except when a notice of termination has
                  been given in accordance with Paragraph 5(b).

2.       The Employee agrees that, during the specified period of employment, he
         shall, to the best of his ability, perform his duties, and shall devote
         his full business time, best efforts, business judgment, skill and
         knowledge to the advancement of the Company and its interests and to
         the discharge of his duties and responsibilities hereunder. The
         Employee shall not engage in any business, profession or occupation
         which would conflict with the rendition of the agreed-upon services,
         either directly or indirectly, without the prior approval of the Board
         of Directors, except for personal investment, charitable and
         philanthropic activities.

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3.       During the period of his employment under this Agreement, the Employee
         shall be compensated for his services as follows:

         a)       Except as otherwise provided in this Agreement, he shall be
                  paid a salary during the period of this Agreement at a base
                  rate to be determined by the Company on an annual basis.
                  Except as provided in Subparagraph 3d, such annual base salary
                  shall under no circumstances be fixed at a rate below the
                  annual base rate then currently in effect;

         b)       He shall be reimbursed for any and all monies expended by him
                  in connection with his employment for reasonable and necessary
                  expenses on behalf of the Company in accordance with the
                  policies of the Company then in effect;

         c)       He shall be eligible to participate under any and all bonus,
                  benefit, pension, compensation, and option plans which are, in
                  accordance with company policy, available to persons in his
                  position (within the limitation as stipulated by such plans).
                  Such eligibility shall not automatically entitle him to
                  participate in any such plan;

         d)       If, because of adverse business conditions or for other
                  reasons, the Company at any time puts into effect salary
                  reductions applicable at a single rate to all management
                  employees of the Company generally, the salary payments
                  required to be made under this Agreement to the Employee
                  during any period in which such general reduction is in effect
                  may be reduced by the same percentage as is applicable to all
                  management employees of the Company generally. Any benefits
                  made available to the Employee which are related to base
                  salary shall also be reduced in accordance with any salary
                  reduction.

4.

         a)       So long as the Employee is employed by the Company and for a
                  period of one year after the termination of expiration of
                  employment, the Employee will not directly or indirectly: (i)
                  as an individual proprietor, partner, stockholder, officer,
                  employee, director, joint venturer, investor, lender, or in
                  any other capacity whatsoever (other than as the holder of not
                  more than one percent (1%) of the total outstanding stock of a
                  publicly held company), engage directly or indirectly in any
                  business or entity which competes with the business conducted
                  by the Company or its affiliates in any city or geographic
                  area in which the company or its affiliates conduct material
                  operations at the time of termination of employment under this
                  Agreement, except as approved in advance by the Board after
                  full and adequate disclosure; or (ii) recruit, solicit or
                  induct, or attempt to induce, any

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                              Employment Agreement
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                  employee or employees of the company to terminate their
                  employment with, to otherwise cease their relationship with,
                  the Company; or (iii) solicit, divert or take away, or attempt
                  to divert or to take away, the business or patronage of any of
                  the clients, customers or accounts, of the Company that were
                  contacted, solicited or served by the Employee while employed
                  by the Company.

         b)       If any restriction set forth in this Section 4 is found by any
                  court of competent jurisdiction to be unenforceable because it
                  extends for too long a period of time or over too great a
                  range of activities or in too broad a geographical area, it
                  shall be interpreted to extend only over the maximum period of
                  time, range of activities or geographic area as to which it
                  may be enforceable.

         c)       The restrictions contained in this Section 4 are necessary for
                  the protection of the business and goodwill of the Company and
                  are considered by the Employee to be reasonable for such
                  purpose. The Employee agrees that any breach of this Section 4
                  will cause the Company substantial and irrevocable damage and
                  therefore, in the event of any such breach, in addition to
                  such other remedies which may be available, the Company shall
                  have the right to seek specific performance and injunctive
                  relief.

         d)       The Employee agrees to sign and be bound by the Employee
                  Patent and Proprietary Information Utilization Agreement in
                  the form attached hereto.

         e)       During the period of his employment by the Company or for any
                  period during which the Company shall continue to pay the
                  Employee his salary under this Agreement, whichever shall be
                  longer, the Employee shall not in any way whatsoever aid or
                  assist any party seeking to cause, initiate or effect a Change
                  in Control of the Company as defined in Paragraph 6 without
                  the prior approval of the Board of Directors.

5.       Except for the Employee covenants set forth in Paragraph 4 which
         covenants shall remain in effect for the periods stated therein, and
         subject to Paragraph 6, this Agreement shall terminate upon the
         happening of any of the following events and (except as provided
         herein) all of the Company's obligations under this Agreement,
         including, but not limited to, making payments to the Employee shall
         cease and terminate:

         a)       On the effective date set forth in any resignation submitted
                  by the Employee and accepted by the Company, or if no
                  effective date is agreed upon, the date of receipt of such
                  resignation letter;

         b)       One year after written notice of termination is given by the
                  Company to the Employee;

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         c)       At the death of the Employee;

         d)       At the termination of the Employee for cause. As used in the
                  Agreement, the term "cause" shall mean:

                  i)       Misappropriating any funds or property of the
                           Company;

                  ii)      Unreasonable refusal to perform the duties assigned
                           to him under this Agreement;

                  iii)     Conviction of a felony;

                  iv)      Continuous conduct bringing notoriety to the Company
                           and having an adverse effect on the name or public
                           image of the Company;

                  v)       Violation of the Employee's covenants as set forth in
                           Paragraph 4 above; or

                  vi)      Continued failure by the Employee to observe any of
                           the provisions of this Agreement after being informed
                           of such breach.

         e)       Twelve months after written notice of termination (a
                  "Disability Termination Notice") is given by the Company to
                  the Employee based on a determination by the Board of
                  Directors that the Employee is disabled (which, for purposes
                  of this Agreement, shall mean that the Employee is unable to
                  perform his regular duties, with such determination to be made
                  by the Board of Directors, in reliance upon the opinion of the
                  Employee's physician or upon the opinion of one or more
                  physicians selected by the Company). A Disability Termination
                  Notice shall be deemed properly delivered if given by the
                  Company to the Employee on the 184th day of continuous
                  disability of the Employee. Notwithstanding the foregoing, if,
                  during the twelve-month period following proper delivery of a
                  Disability Termination Notice as aforesaid, the Employee is no
                  longer disabled and is able to return to work, such Disability
                  Termination Notice shall be deemed automatically rescinded
                  upon the Employee's return to work, and the employment of the
                  Employee shall continue in accordance with the terms of this
                  Agreement. During the first 184 days of continuous disability
                  of the Employee, the Company will make periodic payments to
                  the Employee in an amount equal to the difference between his
                  base salary and the benefits received by the Employee under
                  the Company's Short-Term Disability Income Plan. During the
                  twelve-month period following proper delivery of a Disability
                  Termination Notice as aforesaid, the Company will make
                  periodic

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                  payments to the Employee in an amount equal to the difference
                  between his base salary and the benefits provided by the
                  Company's Long-Term Disability Plan. If any payments to the
                  Employee under the Company's Long-Term Disability Plan are not
                  subject to federal income taxes, the payments to be made
                  directly by the Company pursuant to the preceding sentence
                  shall be reduced such that the total amount received by the
                  Employee (from the Company and from the Long-Term Disability
                  Plan), after payment of any income taxes, is equal to the
                  amount that the Employee would have received had he been paid
                  his base salary, after payment of any income taxes on such
                  base salary.

         f)       In the event of the termination of the Employee by the Company
                  pursuant to paragraph 5(b) above, the Employee shall, for a
                  period of one year from the date this agreement shall
                  terminate, (i) continue to receive his Full Salary (as defined
                  below), which shall be payable in accordance with the payment
                  schedule in effect immediately prior to his employment
                  termination, and (ii) continue to be entitled to participate
                  in all employee benefit plans and arrangements of the Company
                  (such as life, health and disability insurance and automobile
                  arrangements) to the same extent (including coverage of
                  dependents, if any) and upon the same terms as were in effect
                  immediately prior to his termination. For purposes of this
                  Agreement, "Full Salary" shall mean the Employee's annual base
                  salary, plus the amount of any bonus or incentive payments
                  received by the Employee with respect to the last full fiscal
                  year of the Company for which all bonus or incentive payments
                  to be made have been made.

         g)       In the event of a termination of employment pursuant to
                  paragraph 5(a), (c) or (d), the Company shall pay the Employee
                  his full salary through the date of termination of employment.

6.       a)       In the event of a Change in Control of the Company (as defined
                  below), the provisions of this Agreement shall be amended as
                  follows:

                  i)       Paragraph 1a shall be amended to read in its entirety
                           as follows:

                           "Except as hereinafter otherwise provided, the
                           Company agrees to continue to employ the Employee in
                           a management position with the Company, and the
                           Employee agrees to remain in the employment in the
                           Company in that capacity, for a period of three (3)
                           years from the date of the Change in Control. Except
                           as provided in Paragraph 3d, the Employee's salary as
                           set forth in Paragraph 3a and his other employee
                           benefits pursuant to the plans described in Paragraph
                           3c shall not be decreased during such period."

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                  ii)      Paragraph 5a shall be amended by the addition of the
                           following provision at the end of such paragraph:

                           "provided that the Employee agrees not to resign,
                           except for Good Reason (as defined below), during the
                           one-year period following the date of the Change in
                           Control."

                  iii)     Paragraph 5b shall be deleted in its entirety.

                  iv)      Paragraph 5f shall be amended to read in its entirety
                           as follows:

                           "Notwithstanding the foregoing provisions, if, within
                           36 months following the occurrence of a Change in
                           Control, the Employee's employment by the Company is
                           terminated (A) by the Company other than for Cause,
                           which shall not include any failure to perform his
                           duties hereunder after giving notice or termination
                           for Good Reason, disability or death or (B) by the
                           Employee for Good Reason, (1) the Company shall pay
                           to the Employee, on the date of his employment
                           termination, a lump sum cash payment in an amount
                           equal to the sum of (x) his unpaid base salary
                           through the date of termination, (y) prorata portion
                           of prior year's bonus and (z) his Full Salary (as
                           defined below) multiplied by three and (2) the
                           Employee shall for 36 months following the occurrence
                           of the Change in Control be eligible to participate
                           in all employee benefit plans and arrangements of the
                           Company (such as life, health and disability
                           insurance and automobile arrangements but excluding
                           incentive arrangements and grants of stock options)
                           to the same extent (including coverage of dependents,
                           if any) and upon the same terms as were in effect
                           immediately prior to his termination. For purposes of
                           this Agreement, "Full Salary" shall mean the
                           Employee's annual base salary, plus the amount of any
                           bonus or incentive payments received by the Employee
                           with respect to the last full fiscal year of the
                           Company for which all bonus or incentive payments to
                           be made have been made. Payments under this Paragraph
                           5f shall be made without regard to whether the
                           deductibility of such payments (or any other
                           "parachute payments," as that term is defined in
                           Section 280G of the Internal Revenue Code of 1986, as
                           amended (the "Code"), to or for the benefit of the
                           Employee) would be limited or precluded by Section
                           280G and without regard to whether such payments (or
                           any other "parachute payments" as so defined in said
                           Section 280G) would subject the Employee to the
                           federal excise tax levied on certain "excess
                           parachute payments" under Section 4999 of the Code
                           (the "Excise Tax"). In addition, the Employee shall
                           be entitled to receive a payment (the "Gross-Up
                           Payment") which shall be an amount equal to the sum
                           of (a) the Excise Tax imposed on any parachute
                           payment, whether or not

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                           payable under this Agreement, and (b) the amount
                           necessary to pay all additional taxes imposed on (or
                           economically borne by) the Employee (including the
                           Excise Tax, state and federal income taxes and all
                           applicable withholding taxes) attributable to the
                           receipt of the Gross-Up Payment, computed assuming
                           the application of the maximum tax rates provided by
                           law. The determination of the Gross-Up Payment shall
                           be made at the Company's expense by Arthur Andersen &
                           Co. or by such other certified public accounting firm
                           as the Board of Directors of the Company may
                           designate prior to a Change in Control of the
                           Company. In the event of any underpayment or
                           overpayment under this Paragraph 5f as determined by
                           Arthur Andersen & Co. (or such other firm as may have
                           been designated in accordance with the preceding
                           sentence), the amount of such underpayment or
                           overpayment shall forthwith be paid to the Employee
                           or refunded to the Company, as the case may be, with
                           interest at the applicable federal rate provided for
                           in Section 7872(f)(2) of the Code."

                  v)       Paragraph 8 shall be amended to read in its entirety
                           as follows:

                           "The Employee may pursue any lawful remedy he deems
                           necessary or appropriate for enforcing his rights
                           under this Agreement following a Change in Control of
                           the Company, and all costs incurred by the Employee
                           in connection therewith (including without limitation
                           attorneys' fees) shall be promptly reimbursed to him
                           by the Company, regardless of the outcome of such
                           endeavor."

         b)       For purposes of this Agreement, a "Change in Control of the
                  Company" means an event or occurrence set forth in any one or
                  more of clauses (i) through (iv) below (including an event or
                  occurrence that constitutes a Change in Control under one or
                  such clauses but is specifically exempted from another such
                  clause):

                           (i)      the acquisition by an individual, entity or
                  group (within the meaning of Section 13(d)(3) or 14(d)(2) of
                  the Securities Exchange Act of 1934, as amended (the "Exchange
                  Act") (a "Person") of beneficial ownership of any capital
                  stock or the Company if, after such acquisition, such Person
                  beneficially owns (within the meaning of Rule 13d-3
                  promulgated under the Exchange Act) 20% or more of either (1)
                  the then-outstanding shares of common stock of the Company
                  (the "Outstanding Company Common Stock") or (2) the combined
                  voting power of the then-outstanding securities of the Company
                  entitled to vote generally in the election of directors (the
                  "Outstanding Company Voting Securities"); provided, however,
                  that for purposes of this paragraph (i), the following
                  acquisitions shall not constitute a Change in Control: (1) any
                  acquisition directly from the Company

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                  (excluding an acquisition pursuant to the exercise, conversion
                  or exchange of any security exercisable for, convertible into
                  or exchangeable for common stock or voting securities of the
                  Company, unless the Person exercising, converting or
                  exchanging such security acquired such security directly from
                  the Company or an underwriter or agent of the Company), (2)
                  any acquisition by the Company, (3) any acquisition by any
                  employee benefit plan (or related trust) sponsored or
                  maintained by the Company or any corporation controlled by the
                  Company, or (4) any acquisition by any corporation pursuant to
                  a transaction which complies with subclauses (1) and (2) or
                  clause(iii) of this Section 6b; or

                           (ii)     such time as the Continuing Directors (as
                  defined below) do not constitute a majority of the Board (or,
                  if applicable, the Board of Directors of a successor
                  corporation to the Company), where the term "Continuing
                  Director" means at any date a member of the Board (1) who was
                  a member of the Board on the date of the execution of this
                  Agreement or (2) who was nominated or elected subsequent to
                  such date by at least a majority of the directors who were
                  Continuing Directors at the time of such nomination or
                  election or whose election to the Board was recommended or
                  endorsed by at least a majority of the directors who were
                  Continuing Directors at the time of such nomination or
                  election; provided, however, that there shall be excluded from
                  this clause (2) any individual whose initial assumption of
                  office occurred as a result of an actual or threatened
                  election contest with respect to the election or removal of
                  directors or other actual or threatened solicitation of
                  proxies or consents, by or on behalf of a person other than
                  the Board; or

                           (iii)    the consummation of a merger, consolidation,
                  reorganization, recapitalization or statutory share exchange
                  involving the Company or a sale or other disposition of all or
                  substantially all of the assets of the Company (a "Business
                  Combination"), unless, immediately following such Business
                  Combination, each of the following two conditions is
                  satisfied: (1) all or substantially all of the individuals and
                  entities who were the beneficial owners of the Outstanding
                  Company Common Stock and Outstanding Company Voting Securities
                  immediately prior to such Business Combination beneficially
                  own, directly or indirectly, more than 50% of the
                  then-outstanding shares of common stock and the combined
                  voting power of the then-outstanding securities entitled to
                  vote generally in the election of directors, respectively, of
                  the resulting or acquiring corporation in such Business
                  Combination (which shall include, without limitation, a
                  corporation which as a result of such transaction owns the
                  Company or substantially all of the Company's assets either
                  directly or through one or more subsidiaries) (such resulting
                  or acquiring corporation is referred to herein as the
                  "Acquiring Corporation") in substantially the same proportions
                  as their ownership, immediately prior to such

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                  Business Combination, of the Outstanding Company Stock and
                  Outstanding Company Voting Securities, respectively; and (2)
                  no Person (excluding the Acquiring Corporation or any employee
                  benefit plan (or related trust) maintained or sponsored by the
                  Company or by the Acquiring Corporation) beneficially owns,
                  directly or indirectly, 20% or more of the then outstanding
                  shares of common stock of the Acquiring Corporation, or of the
                  combined voting power of the then-outstanding securities of
                  such corporation entitled to vote generally in the election of
                  directors (except to the extent that such ownership existed
                  prior to the Business Combination); or

                           (iv)     approval by the stockholders of the Company
                  or a complete liquidation or dissolution of the Company.

         c)       For purposes of this Agreement, "Good Reason" shall mean the
                  occurrence of any of the following events: (i) a reduction in
                  the Employee's base salary as in effect on the date hereof or
                  as the same may be increased from time to time, except as
                  provided in Paragraph 3d; (ii) a failure by the Company to pay
                  annual cash bonuses to the Employees in an amount at least
                  equal to the most recent annual cash bonuses paid to the
                  Employee; (iii) a failure by the Company to maintain in effect
                  any material compensation or benefit plan in which the
                  Employee participated immediately prior to the Change in
                  Control, unless an equitable arrangement has been made with
                  respect to such plan, or a failure to continue the Employee's
                  participation therein on a basis not materially less favorable
                  than existed immediately prior to the Change in Control; (iv)
                  any significant and substantial diminution in the Employee's
                  position, duties, authorities, responsibilities or title as in
                  effect immediately prior to the Change in Control; (v) any
                  requirement by the Company that the location at which the
                  Employee performs his principal duties be changed to a new
                  location outside a radius of 25 miles from the Employee's
                  principal place of employment immediately prior to the Change
                  in Control;(vi) any requirement by the Company that the
                  Employee travel on an overnight basis to an extent not
                  substantially consistent with the Employee's business travel
                  obligations immediately prior to the Change in Control or
                  (vii) the failure of the Company to obtain the agreement, in a
                  form reasonably satisfactory to the Employee, from any
                  successor to the Company to assume and agree to perform this
                  Agreement. Notwithstanding the foregoing, the resignation
                  shall not be considered to be for Good Reason if any such
                  circumstances are fully corrected prior to the date of
                  resignation. The Employee's right to terminate his employment
                  for Good Reason shall not be affected by his incapacity due to
                  physical or mental illness.

7.       Neither the Employee nor, in the event of his death, his legal
         representative, beneficiary or estate, shall have the power to
         transfer, assign, mortgage or otherwise encumber in advance

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         any of the payments provided for in this Agreement, nor shall any
         payments nor assets or funds of the Company be subject to seizure for
         the payment of any debts, judgments, liabilities, bankruptcy or other
         actions.

8.       Any controversy relating to this Agreement and not resolved by the
         Board of Directors and the Employee shall be settled by arbitration in
         the City of Boston, Commonwealth of Massachusetts, pursuant to the
         rules then obtaining of the American Arbitration Association, and
         judgment upon the award may be entered in any court having
         jurisdiction, and the Board of Directors and Employee agree to be bound
         by the arbitration decision on any such controversy. Unless otherwise
         agreed by the parties hereto, arbitration will be by three arbitrators
         selected from the panel of the American Arbitration Association. The
         full cost of any such arbitration shall be borne by the Company.

9.       Failure to insist upon strict compliance with any of the terms,
         covenants, or conditions hereof shall not be deemed a waiver of such
         term, covenant, or condition, nor shall any waiver or relinquishment of
         any right or power hereunder at any one or more times be deemed a
         waiver or relinquishment of such right or power at any other time or
         times by either party.

10.      All notices or other communications hereunder shall be in writing and
         shall be deemed to have been duly given when delivered personally to
         the Employee or to the General Counsel of the Company or when mailed by
         registered or certified mail to the other party (if to the Company, at
         45 William Street, Wellesley, Massachusetts 02481, attention General
         Counsel; if to the Employee, at the last known address of the Employee
         as set forth in the records of the Company).

11.      This Agreement has been executed and delivered and shall be construed
         in accordance with the laws of the Commonwealth of Massachusetts. This
         Agreement is and shall be binding on the respective legal
         representatives or successors of the parties, but shall not be
         assignable except to a successor to the Company by virtue of a merger,
         consolidation or acquisition of all or substantially all of the assets
         of the Company. This Agreement constitutes and embodies the entire
         understanding and agreement of the parties and, except as otherwise
         provided herein, there are no other agreements or understandings,
         written or oral, in effect between the parties hereto relating to the
         employment of the Employee by the Company. All previous employment
         contracts between the Employee and the Company or any of the Company's
         present or former subsidiaries or affiliates is hereby canceled and of
         no effect.

12.      The Company shall require any successor (whether direct or indirect, by
         purchase, merger, consolidation or otherwise) to all or substantially
         all of the business or assets of the Company to assume expressly in
         writing and to agree to perform its obligations under this

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         Agreement in the same manner and to the same extent that the Company
         would be required to perform it if no such succession had taken place.
         Failure of the Company to obtain an assumption of this Agreement prior
         to the effectiveness of succession shall be a breach of this Agreement.
         As used in this Agreement, "the Company" shall mean the Company as
         defined above and any successor to its business or assets as aforesaid
         which assumes and agrees to perform this Agreement by operation of law,
         or otherwise.

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         IN WITNESS WHEREOF, the Company has caused its seal to be hereunto
affixed and these presents to be signed by its proper officers, and the Employee
has hereunto set his hand and seal the day and year first above written.

(SEAL)                                  PERKINELMER, INC.

                                        By: /s/ Gregory L. Summe
                                            --------------------
                                            Gregory L. Summe
                                            Chairman and Chief Executive Officer

                                        Employee: /s/ Robert F. Friel
                                                  -------------------
                                                  Robert F. Friel

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                              Employment Agreement<PAGE>   1

EXHIBIT 10.24

                              EMPLOYMENT AGREEMENT

            This EMPLOYMENT AGREEMENT (this "Agreement), is made and entered
      into as of the 20th day of November, 2000 (the "Effective Date"), by and
      between INTERLEUKIN GENETICS, INC., a Delaware corporation ("Employer"),
      and Paul Martha, MD., an individual ("Employee").

                                 R E C I T A L S

      A. Employer desires to obtain the benefit of the services of Employee and
Employee desires to render such services to Employer.

      B. The Board of Directors of Employer (the "Board") has determined that it
is in Employer's best interest to employ Employee and to provide certain
benefits to Employee.

      C. Employer and Employee desire to set forth the terms and conditions of
Employee's employment with Employer on the terms and subject to the conditions
of this Agreement

                                A G R E E M E N T

      In consideration of the foregoing recitals and of the mutual covenants and
conditions contained herein, the parties, intending to be legally bound, agree
as follows:

      1.    Term. Employer agrees to employ Employee, and Employee agrees to
serve Employer, in accordance with the terms of this Agreement, for a term (the
"Term") beginning on the Effective Date and continuing for a period of four (4)
years thereafter unless earlier terminated in accordance with the provisions
hereof.

      2.    Employment of Employee.

            (a) Specific Positions. Employer and Employee hereby agree that,
subject to the provisions of this Agreement, Employer will employ Employee and
Employee will serve as an employee of Employer. Employee shall have the title
and perform the duties of Vice President of Medical Affairs and Chief Medical
Officer and such other reasonable, usual and customary duties of such office as
may be delegated to Employee from time to time by the CEO and the Board, subject
always to the policies as reasonably determined from time to time by the Board.

            (b) Promotion of Employer's Business. During the Term, Employee
shall not engage in any business competitive with Employer. Employee agrees to
devote his full business time, attention, knowledge, skill and energy to the
business, affairs and interests of Employer and matters related thereto, and
shall use his best efforts and abilities to promote Employer's

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interests; provided, however, that Employee is not precluded from devoting
reasonable periods to time required: (i) for serving as a director or committee
member of any organization that does not compete with Employer or that does not
involve a conflict of interest with Employer; (ii) for managing his personal
investments; so long as in either case, such activities do not materially
interfere with the regular performance of his duties under this Agreement or
(iii) for delivering lectures. The Company recognizes and acknowledges that for
a period of six months from the employment date, the Employee will have from
time to time the need to consult with his former Employer "Praecis" as long as
such activity does not preclude the Employee from discharging the duties and
responsibilities of his office.

      3.    Salary. Employer shall pay to Employee during the term of this
Agreement a base salary ("Base Salary") of $195,000.00 per year, payable in
equal monthly installments. The Base Salary may be increased (but not decreased)
annually at the Employer's sole discretion throughout the Term on each
anniversary of the Effective Date in the discretion of Employer's Board of
Directors.

      4.    Bonus. In addition to the Base Salary, Employee shall also receive a
bonus, if any, as determined annually by the Board of Directors of Employer in
its sole discretion.

      5.    Benefits.

            (a)   Stock Options. The Employer shall issue to employee stock
                  options to purchase 200,000 shares of the Employer's stock.
                  These options will be issued under the Employer's 2000
                  Employee Stock Compensation Plan. This award is being made
                  effective November 20, 2000, the Employee's hire date. These
                  awards will be covered in detail by separate Option
                  Agreements. The options will vest as follows:

<TABLE>
<S>                                                     <C>
                  20,000                                on May 20, 2001
                    3,333 per month                     June 20, 2001 - November 20, 2001
                    4,167 per month                     December 20, 2001 - November 20, 2002
                    5,000 per month                     December 20, 2002 - November 20, 2003
                    4,167 per month                     December 20, 2003 - October 20, 2004
                    4,161                               November 30, 2004
</TABLE>

                  We will maximize the ISO portion of the award, utilizing the
                  maximum allowable under IRS Code ($100,00 per year). The
                  strike price for the ISO's will be the closing price on the
                  effective date of this agreement. All remaining options will
                  be non-qualified stock options with a strike price based on
                  the closing price on the date this agreement is executed by
                  both parties.

                  In the event there is a Change of Control (as defined in the
                  Company's 2000 Employee Stock Compensation Plan), all
                  outstanding unvested options will immediately vest.

                                       2
<PAGE>   3
            (b)   Fringe Benefits. During Employee's employment by Employer
under this Agreement, Employee shall be eligible for participation in, and shall
be covered by any and all such medical, disability, vision, dental, life, and
other insurance plans and such other similar benefits available to other
employees.

            (c)   Reimbursements. During Employee's employment with Employer
under this Agreement, Employee shall be entitled to receive prompt reimbursement
of all reasonable expenses incurred by Employee in performing services
hereunder, including all expenses of travel at the request of, or in the service
of, Employer provided that such expenses are incurred and accounted for in
accordance with the policies and procedures established by Employer.

            (d)   Vacation. During Employee's employment with Employer
hereunder, Employee shall be entitled to an annual vacation leave of four (4)
weeks at full pay, which shall be adjusted in accordance with the vacation
policy generally applicable to employees of the Employer and Holdings.

      6.    Termination.

            (a) Termination for Cause. Employer shall have the right,
exercisable immediately upon written notice, to terminate Employee's employment
for "Cause."

                  (i) Definition of Cause. As used herein, "Cause" means any of
the following: (A) habitual drunkenness under the influence of alcohol by
Employee or illegal use of narcotics; (B) Employee is convicted by a court of
competent jurisdiction, or pleads "no contest" to, a felony or any other conduct
of a criminal nature (other than minor traffic violations) by Employee; (C)
Employee engages in fraud, embezzlement, or any other illegal conduct; (D)
Employee imparts confidential information relating to Employer or its business
to competitors or to other third parties other than in the course of carrying
out Employee's duties; (E) Employee refuses to perform his duties hereunder or
otherwise breaches any covenant, warranty or representation of this Agreement or
Employee's Non-Disclosure and Confidentiality Agreement executed concurrently
herewith, and, except for any conduct described in clauses (A) through (D) of
this Section 6(a)(i), fails to cure such breach (if such breach is then capable
of being cured) within ten (10) business days following written notice thereof
specifying in reasonable detail the nature of such breach, or if such breach is
not capable of being cured in such time, a cure shall not have been diligently
initiated within such ten (10) business day period.

                  (ii) Effect of Termination. Upon termination in accordance
with this Section 6(a), Employee shall be entitled to no further compensation
hereunder other than the Base Salary and other benefits accrued hereunder
through, but not including, the effective date of such termination. Employer's
exercise of its right to terminate for Cause shall be without prejudice to any
other remedy to which it may be entitled at law, in equity or under this
Agreement.

                                       3
<PAGE>   4
            (b)   Voluntary Termination.  Employee may terminate his employment
at any time by giving no less than thirty (30) days' written notice to Employer.

                  (i) No Reason. Upon termination in accordance with this
Section 6(b), except as otherwise provided in Section 6(b)(ii), below, Employee
shall be entitled to no further compensation hereunder other than the Base
Salary and other benefits accured hereunder through, but not including, the
effective date of such termination.

                  (ii) Good Reason. Notwithstanding anything to the contrary in
Section 6(b)(i), above, if Employee terminates his employment under this Section
6(b) for Good Reason (as defined below), Employee shall be entitled to receive
from Employer all of the compensation and benefits provided for in Section 6(e),
below. As used herein, "Good Reason" means any of the following: (A) the
assignment to Employee of duties materially inconsistent with those of other
employees of Employer in like positions where Employee provides written notice
to Employer within six (6) months of such assignment that such duties are
materially inconsistent with those duties of similarly situated employees and
Employer fails to release Employee from his obligation to perform such
inconsistent duties within twenty (20) business days after Employer's receipt of
such notice; or (B) a failure by Employer to comply with any other material
provision of Sections 3 through 5, inclusive, of this Agreement which has not
been cured within fifteen (15) business days after notice of such noncompliance
has been given by Employee to Employer, or if such failure is not capable of
being cured in such time, a cure shall not have been diligently initiated by
Employer within such fifteen (15) business day period.

            (c) Termination Due to Death or Disability. This Agreement shall
automatically terminate upon the death of Employee. In addition, if Employee is
unable to perform the essential functions of his job with or without a
reasonable accommodation because of a physical or mental impairment for a period
of six (6) months, Employer may terminate Employee's employment upon written
notice to Employee. Upon termination in accordance with this Section 6(c),
Employee (or Employee's estate, as the case may be) shall be entitled to no
further compensation hereunder other than the Base Salary and other benefits
accrued hereunder through, but not including, the date of death or, in the case
of disability, the date or termination.

            (d) Termination Upon Cessation of Business. Employer shall have the
right to immediately terminate Employee's employment under this Agreement upon a
"Cessation of Business." For purposes of this Agreement, a "Cessation of
Business" shall mean Employer's ceasing to operate in the ordinary course of
business, whether by dissolution, liquidation, sale of assets, consolidation,
merger or otherwise, in connection with, pursuant to or arising out of a good
faith determination by the Board that the continuing operation of the business
in its ordinary course is reasonably likely to render Employer unable to meet
its liabilities as they mature. Upon termination in accordance with the Section
6(d), Employee shall be entitled to no further compensation hereunder other than
the Base Salary and other benefits accrued hereunder through, but not including,
the effective date of such termination. If Employee is so terminated by Employer
pursuant to this Section 6(d) during the Term, Employer shall (i) pay to
Employee the Base Salary, and (ii) provide the same health insurance benefits to
which Employee was

                                       4
<PAGE>   5
entitled hereunder, in each case (i.e., the Base Salary and health insurance
benefits), until the earlier to occur of (A) the expiration of the remaining
portion of the Term, or (B) the expiration of the twelve (12) month period
commencing on the date Employee is terminated. Employer may make such payments
in accordance with its regular payroll schedule or in a single lump sum payment
in its sole discretion.

            (e) Termination Without Cause. Employer shall have the right,
exercisable upon 30 days' prior written notice, to terminate Employee's
employment under this Agreement for any reason other than set forth in Sections
6(a), (c) and (d), above, at any time during the Term. If Employee is so
terminated by Employer pursuant to this Section 6(e) during the Term, Employer
shall (i) pay to Employee the Base Salary, and (ii) provide the same health
insurance benefits to which Employee was entitled hereunder, in each case (i.e.,
the Base Salary and health insurance benefits), until the earlier to occur of
(A) the expiration of the remaining portion of the Term, or (B) the expiration
of the twelve (12) month period commencing on the date Employee is terminated.
Employer may make such payments in accordance with its regular payroll schedule
or in a single lump sum payment in its sole discretion.

      7.    Restrictive Covenants.

            (a)   Non-Competition. In consideration of the benefits of this
                  Agreement, including Employee's access to and limited use of
                  proprietary and confidential information of the Company, as
                  well as training, education, and experience provided to
                  Employee by the Company directly and/or as a result of work
                  projects assigned by the Company with respect thereto,
                  Employee hereby covenants and agrees that during the term of
                  this Agreement and for a period of twelve (12) months
                  following termination of this Agreement, regardless of how
                  such termination may be brought about, Employee shall not,
                  directly or indirectly, as proprietor, partner, stockholder,
                  director, officer, employee, consultant, joint venture,
                  investor or in any other capacity, engage in, or own, manager,
                  operate or control, or participate in the ownership,
                  management operation or control of any entity which engages
                  anywhere in the world in any business activity which is
                  competitive to current business activities in which the
                  Company participates during Employee's employment with the
                  Company; provided, however, the foregoing shall not, in any
                  event, prohibit Employee from purchasing and holding as an
                  investment not more than 1% of any class of publicly traded
                  securities of any entity which conducts a business in
                  competition with the business of the Company, so long as
                  Employees does not participate in any way in the management,
                  operation or control of such entity. It is further recognized
                  and agreed that, even though an activity may not be restricted
                  under the foregoing provision, Employee shall not during the
                  term of the Agreement and for a period of twelve (12) months
                  following termination of this Agreement, regardless of how
                  such termination may be brought about, provide any services to
                  any person or entity which may be used against, or in conflict
                  with the interests of, the Company or its customers or
                  clients.

                                       5
<PAGE>   6
            (b)   Judicial Reformation. Employee acknowledges that, given the
                  future of the Company's business, the covenants contained in
                  Section 8(a) establish reasonable limitations as to time,
                  geographic area and scope of activity to be restrained and do
                  not impose a greater restraint than is reasonably necessary to
                  protect and preserve the goodwill of the Company's business
                  and to protect its legitimate business interests. If, however,
                  Section 8(a) is determines by any court of competent
                  jurisdiction to be unenforceable by reason of its extending
                  for too long a period of time or over too large a geographic
                  area or by reason of it being too extensive in any other
                  respect or for any other reason, it will be interpreted to
                  extend only over the longest period of time for which it may
                  be enforceable and/or over the largest geographic areas as to
                  which it may be enforceable and/or to the maximum extent in
                  all other aspects as to which it may be enforceable, all as
                  determined by such court.

            (c)   Customer Lists: Non-Solicitation. In consideration of the
                  benefits of this Agreement, including Employee" access to and
                  limited use of proprietary and confidential information of the
                  Company, as well as training, education and experience
                  provided to Employee by the Company directly and/or as a
                  result of work projects assigned by the Company with respect
                  thereto, Employee hereby further covenants and agrees that for
                  a period of twelve (12) months following the termination of
                  this Agreement, regardless of how such termination may be
                  brought about Employee shall not, directly or indirectly, (I)
                  use or make known to any person or entity the names or
                  addresses of any clients or customers of the Company or any
                  other information pertaining to them (ii) call on for the
                  purpose of competing, solicit, take away or attempt to call
                  on, solicit or take away any clients or customers of the
                  Company on whom Employee called or with whom he became
                  acquainted during his employment with the Company, nor (iii)
                  recruit or attempt to recruit any employees of the Company.

            (d)   Affiliates. When used in this Section 8, the term "Company"
                  includes Interleukin Genetics, Inc. and all affiliates and
                  subsidiaries of Interleukin Genetics, Inc.

      8.    Miscellaneous.

            (a) Withholdings. All payments to Employee hereunder shall be made
after reduction for all federal, state and local withholding and payroll taxes,
all as determined under applicable law and regulations, and Employer shall make
all reports and similar filings required by such law and regulations with
respect to such payments, withholdings and taxes.

            (b) Succession. This Agreement shall inure to the benefit of and
shall be binding upon Employer, its successors and assigns. The obligations and
duties of Employee hereunder shall be personal and not assignable.

            (c) Notices. Any and all notices, demands, requests or other
communications hereunder shall be in writing and shall be deemed duly given when
personally delivered to or transmitted overnight express delivery or by
facsimile to and received by the party to whom such

                                       6
<PAGE>   7
notice is intended (provided the original thereof is sent by mail, in the manner
set forth below, on the next business day after the facsimile transmission is
sent), or in lieu of such personal delivery or overnight express delivery or
facsimile transmission, on receipt when deposited in the United States mail,
first-class, certified or registered, postage prepaid, return receipt requested,
addressed to the applicable party at the address set forth below such party's
signature to this Agreement. The parties may change their respective addresses
for the purpose of this Section 8(c) by giving notice of such change to the
other parties in the manner which is provided in this Section 8(c).

            (d) Entire Agreement. This Agreement together with the Stock Option
Agreement contains the entire agreement of the parties relating to the subject
matter hereof, and it replaces and supersedes any prior agreements between the
parties relating to said subject matter.

            (e) Headings. The headings of Sections herein are used for
convenience only and shall not affect the meaning of contents hereof.

            (f) Waiver; Amendment. No provision hereof may be waived except by a
written agreement signed by the waiving party. The waiver of any term or of any
condition of this Agreement shall not be deemed to constitute the waiver of any
other term or condition. This Agreement may be amended only by a written
agreement signed by the parties hereto.

            (g) Severability. If any of the provisions of this Agreement shall
be held unenforceable by the final determination of a court of competent
jurisdiction and all appeals therefrom shall have failed or the time for such
appeals shall have expired, such provision or provisions shall be deemed
eliminated from this Agreement but the remaining provisions shall nevertheless
be given full effect. In the event this Agreement or any portion hereof is more
restrictive than permitted by the law of the jurisdiction in which enforcement
is sought, this Agreement or such portion shall be limited in that jurisdiction
only to the extent required by the law of that jurisdiction.

            (h) Governing Law. This Agreement shall be governed by and construed
in accordance with the laws of the Commonwealth of Massachusetts.

            (i) Arbitration. Any dispute arising out of or relating to this
Agreement, or the breach, termination or the validity hereof, shall be settled
by arbitration in accordance with the Commercial Arbitration Rules of the
American Arbitration Association. Judgment upon the award rendered by the
arbitrator or arbitrators may be entered in any court having jurisdiction
thereof. THE ARBITRATOR OR ARBITRATORS ARE NOT EMPOWERED TO AWARD DAMAGES IN
EXCESS OF COMPENSATORY DAMAGES (INCLUDING REASONABLE ATTORNEYS FEES AND EXPERT
WITNESS FEES) AND EACH PARTY HEREBY IRREVOCABLY WAIVES ANY RIGHT TO RECOVER SUCH
DAMAGES (INCLUDING, WITHOUT LIMITATION, PUNITIVE DAMAGES) IN ANY FORUM. The
arbitrator or arbitrators may award equitable relief in those circumstances
where monetary damages would be inadequate. The arbitrator or arbitrators shall
be required to follow the applicable law as set

                                       7
<PAGE>   8
forth in the governing law section of this Agreement. The arbitrator or
arbitrators shall award reasonable attorneys fees and costs of arbitration to
the prevailing party in such arbitration.

      IN WITNESS WHEREOF, the parties have executed this Agreement as of the
date first set forth above.

"EMPLOYER":                               "EMPLOYEE":

INTERLEUKIN GENETICS, INC.

By:________________________________       ___________________________________
   PHILIP R. REILLY, MD, JD               PAUL MARTHA, MD

Address:                                  Address:

135 Beaver Street - Second Floor          101 Hill Street
Waltham, MA  02452                        Topsfield, MA  01983

                                       8

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