赤堀氨基酸反应 赤堀氨基酸反应Akabori amino acid reaction有两种 α氨基酸在加热时被氧化性糖氧化 α氨基酸及其酯类被钠汞齐在氯化氢的乙醇溶液中还原生成 α氨基醛 There are several Akabori amino acid reactions which are named after Shirō Akabori jap 赤堀 四郎  a Japanese chemist In the first reaction an αamino acid is oxidised and undergoes decarboxylation to give an aldehyde at the former α position by heating with oxygen in the presence of a reducing sugar This reaction is useful for preparing dichlorophthalimido derivatives具体情况如何 of peptides for mass spectral analysis In the second reaction an αamino acid or an ester of it is reduced by sodium amalgam and ethanolic HCl to give an αamino aldehyde This process is conceptually similar to the BouveaultBlanc reduction except that it stops at the aldehyde stage rather than reducing the ester all the way to two alcohols