コクシエラ属

コクシエラ属又はコキシエラ属（ーぞく、Coxiella)はPseudomonadota門ガンマプロテオバクテリア綱レジオネラ目コクシエラ科の属の一つである。グラム陰性の芽胞形成偏性細胞内寄生性細菌である。生態がリケッチア属に類似していたためかつてはリケッチア科であったが、遺伝子の解析により再分類されて2024年現在はコクシエラ科に属し、その基準属である。コクシエラ・バーネッティイ（Coxiella burnetii）のみが知られている。名称はアメリカの微生物学者、ハロルド・コックス（Herald Rea Cox）に因む。GC含量は43。 脊椎動物や節足動物に寄生し、病原性がある。ヒトの場合、Q熱の病原体となる。偏性細胞内寄生性であるが、芽胞を形成するため、細胞外でもある程度の期間生き延びることができる。そのため、飛沫感染が可能である。 以下の種を含む(2024年9月現在)。 Coxiella burnetii　コクシエラ・バーネッティイ (Derrick 1939) Philip 1948 (IJSEMリストに掲載 1980) "Candidatus Coxiella avium" Trinachartvanit et al. 2018 (IJSEMリストに掲載 2020) "Candidatus Coxiella cheracis" corrig. Elliman & Owens 2020 (IJSEMリストに掲載 2022) "Candidatus Coxiella massiliensis" Angelakis et al. 2016 (IJSEMリストに掲載 2022) "Candidatus Coxiella mudrowiae" Gottlieb et al. 2015 (IJSEMリストに掲載 2020) "Coxiella cheraxi" Tan & Owens 2000 "Coxiella popilliae" Dutky & Gooden 1952 現在はRickettsiella popilliae（リケッチエラ・ポピリアエ）のシノニムとされる。 [脚注の使い方] ^ a b c Cornelius B. Philip (Jan. 9, 1948). “Comments on the Name of the Q Fever Organism”. Public Health Reports (Sage Publications, Inc.) 63 (2): 58. doi:10.2307/4586402.  ^ a b c V. B. D. Skerman, Vicki McGowan and P. H. A. Sneath (01 January 1980). “Approved Lists of Bacterial Names”. International Journal of Systematic and Evolutionary Microbiology: 225-420. doi:10.1099/00207713-30-1-225.  ^ Navneet Saini & Radhey S. Gupta (21 April 2021). “A robust phylogenetic framework for members of the order Legionellales and its main genera (Legionella, Aquicella, Coxiella and Rickettsiella) based on phylogenomic analyses and identification of molecular markers demarcating different clades” (英語). Antonie van Leeuwenhoek 114 (7): 957–982. doi:10.1007/s10482-021-01569-9. ISSN 0003-6072. https://link.springer.com/10.1007/s10482-021-01569-9.  ^ a b E. H. Derrick (01 January 1939). “RICKETTSIA BURNETI: THE CAUSE OF “Q” FEVER”. Medical Journal of Australia 1 (1): 14-14. doi:10.5694/j.1326-5377.1939.tb98379.x.  ^ Jean P. Euzéby, Aidan C. Parte. “Genus Coxiella”. List of Prokaryotic names with Standing in Nomenclature (LPSN). 2024年9月15日閲覧。 ^ Wachareeporn Trinachartvanit 1, Simaporn Maneewong 1, Warissara Kaenkan 1, Pawiga Usananan 1, Visut Baimai 1 2, Arunee Ahantarig 3 4 (1: Biodiversity Research Cluster, Department of Biology, Faculty of Science, Mahidol University, Rama 6 Road, Bangkok, 10400, Thailand, 2: Center of Excellence for Vectors and Vector-Borne Diseases, Faculty of Science, Mahidol University at Salaya, Phutthamonthon 4 Road, Nakhon Pathom, 73170, Thailand, 3: Biodiversity Research Cluster, Department of Biology, Faculty of Science, Mahidol University, Rama 6 Road, Bangkok, 10400, Thailand, 4: Center of Excellence for Vectors and Vector-Borne Diseases, Faculty of Science, Mahidol University at Salaya, Phutthamonthon 4 Road, Nakhon Pathom, 73170, Thailand) (27 December 2018). “Coxiella-like bacteria in fowl ticks from Thailand”. Parasites & Vectors 11 (1): 670. doi:10.1186/s13071-018-3259-9. PMC 6307260. PMID 30587229. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307260/.  ^ a b c Aharon Oren1, George M. Garrity2,3, Charles T. Parker3, Maria Chuvochina4 and Martha E. Trujillo5 (1: The Institute of Life Sciences, The Hebrew University of Jerusalem, The Edmond J. Safra Campus, 9190401 Jerusalem, Israel, 2: Department of Microbiology & Molecular Genetics, Biomedical Physical Sciences, Michigan State University, East Lansing, MI 48824-4320, USA, 3: NamesforLife, LLC, PO Box 769, Okemos MI 48805-0769, USA, 4: Australian Centre for Ecogenomics, University of Queensland, St. Lucia QLD 4072, Brisbane, Australia, 5: Departamento de Microbiología y Genética, Campus Miguel de Unamuno, Universidad de Salamanca, 37007, Salamanca, Spain) (30 June 2020). “Lists of names of prokaryotic Candidatus taxa”. International Journal of Systematic and Evolutionary Microbiology 70 (7): 3956-4042. doi:10.1099/ijsem.0.003789.  ^ J Ruth Elliman 1, L Owens 1 (1: College of Public Health, Biomedicine and Veterinary Science, James Cook University, Douglas, Qld, Australia). “Confirmation that candidatus Coxiella cheraxi from redclaw crayfish (Cherax quadricarinatus) is a close relative of Coxiella burnetii, the agent of Q‐fever Get access Arrow”. Letters in Applied Microbiology, Volume 71, Issue 3, 1 September 2020, Pages 320–326. doi:10.1111/lam.13336. PMID 32491210.  ^ Aharon Oren1 and George M. Garrity2 (1: The Institute of Life Sciences, The Hebrew University of Jerusalem, The Edmond J. Safra Campus, 9190401 Jerusalem, Israel, 2: Department of Microbiology & Molecular Genetics, Biomedical Physical Sciences, Michigan State University, East Lansing, MI 48824-4320, USA) (31 January 2022). “CANDIDATUS LIST No. 3. Lists of names of prokaryotic Candidatus taxa”. International Journal of Systematic and Evolutionary Microbiology 72 (1): 5186. doi:10.1099/ijsem.0.005186.  ^ Emmanouil Angelakis, Oleg Mediannikov, Sarah-Lyne Jos, Jean-Michel Berenger, Philippe Parola, and Didier Raoult (Author affiliations: Aix Marseille Université, Marseille, France) (February 2016). “Candidatus Coxiella massiliensis Infection”. Emerging Infectious Diseases 22 (2): 285-8. doi:10.3201/eid2202.150106. PMC 4734529. PMID 26811945. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4734529/.  ^ Yuval Gottlieb 1, Itai Lalzar 1, Lisa Klasson 2 (1: Koret School of Veterinary Medicine, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, Israel, 2: Molecular Evolution, Department of Cell and Molecular Biology, Uppsala University, Sweden) (28 May 2015). “Distinctive Genome Reduction Rates Revealed by Genomic Analyses of Two Coxiella- Like Endosymbionts in Ticks”. Genome Biology and Evolution 7 (6). doi:10.1093/gbe/evv108. PMC 4494066. PMID 26025560. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494066/.  ^ C. K. Tan, L. Owens (Department of Microbiology and Immunology, James Cook University, Townsville 4811, Australia (2000 Jun 19). “Infectivity, transmission and 16S rRNA sequencing of a rickettsia, Coxiella cheraxi sp. nov., from the freshwater crayfish Cherax quadricarinatus”. Diseases of Aquatic Organisms 41 (2): 115-22. doi:10.3354/dao041115. PMID 10918979.  ^ S. R. Dutky, E. L. Gooden (1 June 1952). “Coxiella popilliae, n. sp., a rickettsia causing blue disease of Japanese beetle larvae”. Journal of Bacteriology 63 (6): 743-50. doi:10.1128/jb.63.6.743-750.1952. PMC 169624. PMID 14938336. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC169624/.  Michael T. Madiganほか著、室伏きみ子、関啓子監訳『Brock微生物学』オーム社、2003年4月。ISBN 9784274024887。 NCID BA61734511。  発酵研究所監修、大嶋泰治ほか編『IFO微生物学概論』培風館、2010年12月。ISBN 9784563078119。 NCID BB04312618。