歯根膜炎

歯根膜炎（しこんまくえん）は歯根膜、すなわち歯根とその周囲の歯槽骨の間にあるきわめて狭い隙間を満たしている結合組織の炎症である。 歯根膜炎は、C反応性タンパク質とインターロイキン-6のレベルの上昇によって示されるように、体内の炎症の増加 心筋梗塞、 アテローム性動脈硬化症 および高血圧のリスク増加と関連している 。また、60歳以上の人では、記憶力と計算能力の遅延に関連していたが 空腹時血糖異常および糖尿病患者は歯周炎の程度が高く、歯周炎によって一定引き起こされる全身性炎症状態のために血糖値のバランスをとることが困難なことが顕著で 因果関係は証明されていないが、慢性歯周炎と勃起不全 炎症性腸疾患 心臓病 および膵臓癌と関連が疑われている ^ “Gum Disease”. National Institute of Dental and Craniofacial Research (2018年2月). 2018年3月13日閲覧。 ^ “Periodontitis and systemic inflammation: control of the local infection is associated with a reduction in serum inflammatory markers”. Journal of Dental Research 83 (2): 156–60. (February 2004). doi:10.1177/154405910408300214. PMID 14742655.  ^ “Severe periodontitis is associated with systemic inflammation and a dysmetabolic status: a case-control study”. Journal of Clinical Periodontology 34 (11): 931–7. (November 2007). doi:10.1111/j.1600-051X.2007.01133.x. PMID 17877746.  ^ “A systematic review and meta-analyses on C-reactive protein in relation to periodontitis”. 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