血液検査の参考基準値

血液検査の参考基準値（けつえきけんさのさんこうきじゅんち、英語: Reference ranges for blood tests）は、保健専門家が血液サンプルからの医学的検査結果一式を説明する際に使われる参考基準値である。 血液検査の参考基準値は、体液の分析に関心を有する病理学に関連した臨床化学（臨床生化学、化学的病理学、純血液化学としても知られている）の分野で研究されている。 鉄と結びつくフェリチンやトランスフェリン、銅と結びつくセルロプラスミンのような結合たんぱく質もここに含むこととする。 酸塩基及び血中ガスについて動脈・静脈の別を特定しなければ、血液検査の結果が正常範囲であるのか否か判断することができない。 酸塩基及び血液ガスは項目が少ないが、動脈・静脈の別で数値が根本的に異なってくる。 痛みの始まりから12時間後のトロポニンの値: [脚注の使い方] ^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af ag ah ai aj ak al am an ao ap aq ar as at au av aw ax ay az ba bb bc bd be bf bg bh bi bj bk bl bm bn bo bp bq br bs bt bu bv bw bx by bz ca cb cc cd ce cf cg ch ci cj ck cl cm cn co cp cq cr cs ct cu cv cw cx cy cz da db dc dd Last page of Deepak A. Rao; Le, Tao; Bhushan, Vikas (2007). First Aid for the USMLE Step 1 2008 (First Aid for the Usmle Step 1). McGraw-Hill Medical. ISBN 0-07-149868-0  ^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af ag ah ai aj ak al am an ao ap aq ar as at au av aw ax ay az ba bb bc bd be bf bg bh bi bj bk bl bm bn bo bp bq br bs bt bu bv bw bx by bz ca cb cc cd ce cf cg ch ci cj ck cl cm cn co cp cq cr cs ct cu cv cw cx cy cz da db dc Normal Reference Range Table from The University of Texas Southwestern Medical Center at Dallas. Used in Interactive Case Study Companion to Pathologic basis of disease. ^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af ag ah ai aj ak al am an ao ap aq ar as at au av aw ax ay az ba bb bc bd be bf bg bh bi bj bk bl bm bn bo bp bq br bs bt bu bv bw bx by bz ca cb cc cd ce cf cg ch ci cj ck cl cm cn co cp cq cr cs ct cu cv cw cx cy cz da db dc dd de df dg dh di dj dk dl dm dn do dp dq dr ds dt du dv dw dx Reference range list from Uppsala University Hospital ("Laborationslista"). Artnr 40284 Sj74a. Issued on April 22, 2008 ^ a b c d Derived from molar values using molar mass of 22.99 g•mol−1 ^ a b Derived from molar values using molar mass of 39.10 g•mol−1 ^ a b c d e f g h i j k l m MERCK MANUALS > Common Medical Tests > Blood Tests Last full review/revision February 2003 ^ a b Derived from molar values using molar mass of 35.45 g•mol−1 ^ a b Larsson L, Ohman S (November 1978). “Serum ionized calcium and corrected total calcium in borderline hyperparathyroidism”. Clin. Chem. 24 (11): 1962-5. PMID 709830. http://www.clinchem.org/cgi/pmidlookup?view=long&pmid=709830.  ^ a b c d Derived from molar values using molar mass of 40.08  g•mol−1 ^ a b c d e f g h i j k l Slon S (2006年9月22日). “Serum Iron”. University of Illinois Medical Center. 2006年7月6日閲覧。 ^ a b c d Diagnostic Chemicals Limited > Serum Iron-SL Assay July 15, 2005 ^ a b c d e f g h i j k l m Derived from mass values using molar mass of 55.85 g•mol−1 ^ a b Table 1. Page 133. Clinical Chemistry 45, No. 1, 1999 (stating 1.9–3.3 g/L) ^ a b Derived by dividing mass values with molar mass ^ a b c d Ferritin by: Mark Levin, MD, Hematologist and Oncologist, Newark, NJ. Review provided by VeriMed Healthcare Network ^ a b c d Derived from mass values using molar mass of 450,000 g•mol−1 ^ a b Mitchell ML, Filippone MD, Wozniak TF (August 2001). “Metastatic carcinomatous cirrhosis and hepatic hemosiderosis in a patient heterozygous for the H63D genotype”. Arch. Pathol. Lab. Med. 125 (8): 1084-7. PMID 11473464. http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0003-9985&volume=125&page=1084.  ^ a b Diaz J, Tornel PL, Martinez P (July 1995). “Reference intervals for blood ammonia in healthy subjects, determined by microdiffusion”. Clin. Chem. 41 (7): 1048. PMID 7600690.  ^ a b c d Derived from molar values using molar mass of 17.03 g/mol ^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af ag ah ai aj ak al am an ao ap aq ar as at au av aw ax ay az ba bb bc bd be bf bg bh bi bj bk bl bm bn bo bp bq br bs bt bu bv bw bx by Blood Test Results - Normal Ranges Bloodbook.Com ^ a b Derived from mass values using molar mass of 63.55 g•mol−1 ^ a b Derived from mass using molar mass of 151kDa ^ a b c Derived from mass values using molar mass of 40.08  g•mol−1 ^ Walter F., PhD. Boron (2005). Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. ISBN 1-4160-2328-3  Page 849 ^ Reference range for copper - GPnotebook ^ a b http://www.dlolab.com/PDFs/DLO-OCTOBER-2008-LAB-UPDATE.pdf ^ a b Derived from molar values using molar mass of 65.38 g/mol ^ a b Derived from mass values using molar mass of 65.38 g/mol ^ a b Derived from molar values using molar mass of 24.31 g/mol ^ a b Derived from mass values using molar mass of 24.31 g/mol ^ a b c d e f g h i j k l m n o Adëeva Nutritionals Canada > Optimal blood test values Retrieved on July 9, 2009 ^ Middleton P, Kelly AM, Brown J, Robertson M (August 2006). “Agreement between arterial and central venous values for pH, bicarbonate, base excess, and lactate”. Emerg Med J 23 (8): 622-4. doi:10.1136/emj.2006.035915. PMC 2564165. PMID 16858095. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2564165/.  ^ a b c d e f g h i j k l The Medical Education Division of the Brookside Associates--> ABG (Arterial Blood Gas) Retrieved on Dec 6, 2009 ^ a b Derived from molar values using molar mass of 1.01 g•mol−1 ^ a b c d e f g h Derived from mmHg values using 0.133322 kPa/mmHg ^ a b Derived from molar values using molar mass of 44.010 g/mol ^ a b c d Derived from molar values using molar mass of 61 g/mol ^ Reference range (albumin) - GPnotebook ^ a b Derived from mass using molecular weight of 65kD ^ a b c d e Derived from mass values using molar mass of 585g/mol ^ a b Derived from molar values using molar mass of 585g/mol ^ a b c d e f g h i j k l m n o p q r s Fachwörterbuch Kompakt Medizin E-D/D-E. Author: Fritz-Jürgen Nöhring. Edition 2. Publisher:Elsevier, Urban&FischerVerlag, 2004. ISBN 3437151207, 9783437151200. Length: 1288 pages ^ a b c d GPnotebook > reference range (AST) Retrieved on Dec 7, 2009 ^ a b Helander A, Vabö E, Levin K, Borg S (October 1998). “Intra- and interindividual variability of carbohydrate-deficient transferrin, gamma-glutamyltransferase, and mean corpuscular volume in teetotalers”. Clin. Chem. 44 (10): 2120-5. PMID 9761244.  ^ a b Creatine kinase - GPnotebook ^ a b c d e f g h i j k l m n o p Saint Francis Hospital Laboratory > BNP reference range change Jay Hupp & Dr. Michel S. Medawar. Effective November, 2002 ^ a b c d e f g h i j The University of Iowa (UIHC) > Department of Pathology > LABORATORY SERVICES HANDBOOK > N-terminal-pro-BNP Showing 95th percentiles. Epic Lab Code: LAB649. Updated: 10/27/2009 ^ a b c d Muscle Information and Courses from MediaLab, Inc. > Cardiac Biomarkers Retrieved on April 22, 2010 ^ a b c d e f g h i j South London Healthcare NHS Trust ^ a b c Moderately Elevated Serum Troponin Concentrations Are Associated With Increased Morbidity and Mortality Rates in Surgical Intensive Care Unit Patients Rene P. Relos, MD; Ian K. Hasinoff, MD; Greg J. Beilman, MD. Posted: 12/05/2003; Crit Care Med. 2003;31(11) ^ a b Kay SE, Doery J, Sholl D (February 2002). “Clozapine associated pericarditis and elevated troponin I”. Aust N Z J Psychiatry 36 (1): 143-4. doi:10.1046/j.1440-1614.2002.0988f.x. PMID 11929456.  ^ GP Notebook > range (reference, ca-125) Retrieved on Jan 5, 2009 ^ ClinLab Navigator > Test Interpretations > CA-125 Retrieved on Jan 5, 2009 ^ a b Bjerner J, Høgetveit A, Wold Akselberg K, et al. (June 2008). “Reference intervals for carcinoembryonic antigen (CEA), CA125, MUC1, Alfa-foeto-protein (AFP), neuron-specific enolase (NSE) and CA19.9 from the NORIP study”. Scandinavian journal of clinical and laboratory investigation 68 (8): 1-12. doi:10.1080/00365510802126836. PMID 18609108.  ^ Carcinoembryonic Antigen(CEA) at MedicineNet ^ The TSH Reference Range Wars: What's "Normal?", Who is Wrong, Who is Right... By Mary Shomon, About.com. Updated: June 19, 2006. About.com Health's Disease and Condition ^ a b 2006 Press releases: Thyroid Imbalance? Target Your Numbers Contacts: Bryan Campbell American] Association of Clinical Endocrinologists ^ a b The TSH Reference Range Wars: What's "Normal?", Who is Wrong, Who is Right... By Mary Shomon, About.com. Updated: June 19, 2006 ^ a b Demers, Laurence M.; Carole A. Spencer (2002年). “LMPG: Laboratory Support for the Diagnosis and Monitoring of Thyroid Disease”. en:National Academy of Clinical Biochemistry (USA). 2007年4月13日閲覧。 - see Section 2. Pre-analytic factors ^ a b c d e f g h i j Free T4; Thyroxine, Free; T4, Free UNC Health Care System ^ a b c d e f g h i j Derived from mass values using molar mass of 776.87 g/mol ^ a b c d e f g h i j k l m n o Table 4: Typical reference ranges for serum assays - Thyroid Disease Manager ^ a b c d Euthyroid Patient with Elevated Serum Free Thyroxine George van der Watt1,a, David Haarburger1 and Peter Berman ^ a b c d Derived from mass values using molar mass of 650.98 g/mol ^ a b Serum concentration of free T3, free T4 and TSH in healthy children Cioffi Michele; Gazzerro Patrizia; Vietri Maria Teresa; Magnetta Rosa; Durante Adriana; D'Auria Annamaria; Puca Giovanni Alfredo; Molinari Anna Maria ; ^ a b Andrology Australia: Your Health > Low Testosterone > Diagnosis ^ a b c d Derived from mass values using molar mass of 288.42g/mol ^ a b c d e f g Derived from molar values using molar mass of 288.42g/mol ^ a b c d MedlinePlus > Testosterone Update Date: 3/18/2008. Updated by: Elizabeth H. Holt, MD, PhD, Yale University. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director ^ a b c d e f g h i j reference range (FSH) GPnotebook. Retrieved on September 27, 2009 ^ a b c d e f g h Values taken from day 1 after LH surge in: Establishment of detailed reference values for luteinizing hormone, follicle stimulating hormone, estradiol, and progesterone during different phases of the menstrual cycle on the Abbott ARCHITECT analyzer. Reto Stricker, Raphael Eberhart, Marie-Christine Chevailler, Frank A. Quinn, Paul Bischof and Rene´ Stricker. Clin Chem Lab Med 2006;44(7):883–887 PMID 16776638 ^ a b c d e f New York Hospital Queens > Services and Facilities > Patient Testing > Pathology > New York Hospital Queens Diagnostic Laboratories > Test Directory > Reference Ranges Retrieved on Nov 8, 2009 ^ a b c d e f g h i j GPNotebook - reference range (oestradiol) Retrieved on September 27, 2009 ^ a b c d e f g h i j k l Derived from molar values using molar mass of 272.38g/mol ^ a b c d Total amount multiplied by 0.022 according to 2.2% presented in: Wu CH, Motohashi T, Abdel-Rahman HA, Flickinger GL, Mikhail G (August 1976). “Free and protein-bound plasma estradiol-17 beta during the menstrual cycle”. J. Clin. Endocrinol. Metab. 43 (2): 436-45. doi:10.1210/jcem-43-2-436. PMID 950372.  ^ a b Derived from molar values using molar mass of 314.46 g/mol ^ a b Derived from mass values using molar mass of 4540g/mol according to PROOPIOMELANOCORTIN; NCBI --> POMC Retrieved on September 28, 2009 ^ “Adrenocorticotropic Hormone:Normal”. WebMD (09-03-2006). 2008年11月9日閲覧。 ^ Derived from molar values using molar mass of 4540g/mol according to PROOPIOMELANOCORTIN; NCBI --> POMC Retrieved on September 28, 2009 ^ a b c d Biochemistry Reference Ranges at Good Hope Hospital Retrieved on Nov 8, 2009 ^ a b c d Derived from molar values using molar mass of 362 g/mol ^ a b Derived from molar values using molar mass of 9.4 kDa ^ a b Table 2 in: Aloia JF, Feuerman M, Yeh JK (2006). “Reference range for serum parathyroid hormone”. Endocr Pract 12 (2): 137-44. PMC 1482827. PMID 16690460. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1482827/.  ^ a b Derived from mass values using molar mass of 9.4 kDa ^ a b c d e f Derived from molar values using molar mass 400.6 g/mol ^ a b c d Bender, David A. (2003). “Vitamin D”. Nutritional biochemistry of the vitamins. Cambridge: Cambridge University Press. ISBN 0-521-80388-8. https://books.google.com/?id=pxEJNs0IUo4C  Retrieved December 10, 2008 through Google Book Search. ^ a b c d Bischoff-Ferrari, H.A., Dietrich, T., Orav, J.E., Hu, F.B., Zhang, Y., Karlson, E., Dawson-Hughes, B. 2004. Higher 25-hydroxyvitamin D levels are associated with better lower extremity function in both active and inactive adults 60+ years of age. American Journal of Clinical Nutrition. 80:752-758. ^ a b c d Reusch J, Ackermann H, Badenhoop K (May 2009). “Cyclic changes of vitamin D and PTH are primarily regulated by solar radiation: 5-year analysis of a German (50 degrees N) population”. Horm. Metab. Res. 41 (5): 402-7. doi:10.1055/s-0028-1128131. PMID 19241329.  ^ a b c d e f g h Letter: Calcium and vitamin D in preventing fractures. Data are not sufficient to show inefficacy Alex Vasquez, researcher. BMJ 2005;331:108-109 (9 July), doi:10.1136/bmj.331.7508.108-b. ^ a b c d e f g h The Doctor's Doctor: Homocysteine ^ a b c d e f g h Derived from molar values using molar massof 135 g/mol ^ a b c d e f Central Manchester University Hospitals --> Reference ranges Retrieved on July 9, 2009 ^ University of Kentucky Chandler Medical Center > Clinical Lab Reference Range Guide Retrieved on April 28, 2009 ^ a b c d e Derived from mass values using molar mass of 441 mol−1 ^ a b GPnotebook > B12 Retrieved on April 28, 2009 ^ a b Derived form molar values using molar mass of 1355g/mol ^ a b Derived from mass values using molar mass of 1355g/mol ^ a b Derived from mass values using molar mass of 176 grams per mol ^ a b c For en:Driving under the influence by country, see en:Drunk driving law by country ^ Derived from mass values using molar mass of 46g/mol ^ a b c d e Derived from mass values using 64,500 g/mol, according to Van Beekvelt MC, Colier WN, Wevers RA, Van Engelen BG (2001). “Performance of near-infrared spectroscopy in measuring local O2 consumption and blood flow in skeletal muscle”. J Appl Physiol 90 (2): 511-519. PMID 11160049.  ^ a b c d Derived from mass concentration, using molar mass of 64,458 g/mol (Van Beekvelt MC, Colier WN, Wevers RA, Van Engelen BG (2001). “Performance of near-infrared spectroscopy in measuring local O2 consumption and blood flow in skeletal muscle”. J Appl Physiol 90 (2): 511-519. PMID 11160049. ). 1 g/dL = 0.1551 mmol/L ^ a b c d e f g h lymphomation.org > Tests & Imaging > Labs > Complete Blood Count Retrieved on May 14, 2009 ^ a b c d e f g h i j k l m n o p q r s t u Clinical Laboratory Medicine. By Kenneth D. McClatchey. Page 807. ^ Determination of monocyte count by hematological analyzers, manual method and flow cytometry in polish population Central European Journal of Immunology 1-2/2006. (Centr Eur J Immunol 2006; 31 (1-2): 1-5) authors: Elżbieta Górska, Urszula Demkow, Roman Pińkowski, Barbara Jakubczak, Dorota Matuszewicz, Jolanta Gawęda, Wioletta Rzeszotarska, Maria Wąsik, ^ a b c d e gpnotebook.co.uk > blood constituents (reference range) Retrieved on may 14, 2009 ^ a b MedlinePlus Encyclopedia 003652 ^ a b [1] Retrieved on November 20, 2009 ^ a b Miller A, Green M, Robinson D (1983). “Simple rule for calculating normal erythrocyte sedimentation rate”. Br Med J (Clin Res Ed) 286 (6361): 266. doi:10.1136/bmj.286.6361.266. PMC 1546487. PMID 6402065. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1546487/.  ^ Böttiger LE, Svedberg CA (1967). “Normal erythrocyte sedimentation rate and age”. Br Med J 2 (5544): 85-7. doi:10.1136/bmj.2.5544.85. PMC 1841240. PMID 6020854. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1841240/.  ^ C-reactive protein - GPnotebook ^ 2730 Serum C-Reactive Protein values in Diabetics with Periodontal Disease A.R. Choudhury, and S. Rahman, Birdem, Diabetic Association of Bangladesh, Dhaka, Bangladesh. (the diabetics were not used to determine the reference ranges) ^ a b c d Derived from mass using molar mass of 25,106 g/mol ^ a b Sipahi T, Kara C, Tavil B, Inci A, Oksal A (March 2003). “Alpha-1 antitrypsin deficiency: an overlooked cause of late hemorrhagic disease of the newborn”. J. Pediatr. Hematol. Oncol. 25 (3): 274-5. doi:10.1097/00043426-200303000-00019. PMID 12621252. http://www.jpho-online.com/pt/re/jpho/fulltext.00043426-200303000-00019.htm.  ^ a b Derived from mass values using molar mass of 44324.5 g/mol ^ a b Derived from molar values using molar mass of 44324.5 g/mol ^ a b c d e f g h i j The Society for American Clinical Laboratory Science > Chemistry Tests > Immunoglobulins Retrieved on Nov 26, 2009 ^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af ag ah ai aj ak al am an ao ap aq chronolab.com > Autoantibodies associated with rheumatic diseases > Reference ranges Retrieved on April 29, 2010 ^ Reference range (amylase) - GPnotebook ^ Plasma Measurement of D-Dimer Levels for the Early Diagnosis of Ischemic Stroke Subtypes Walter Ageno, MD; Sergio Finazzi, MD; Luigi Steidl, MD; Maria Grazia Biotti, MD; Valentina Mera, MD; GianVico Melzi d'Eril, MD; Achille Venco, MD. Arch Intern Med. 2002;162:2589-2593. ^ Kline JA, Williams GW, Hernandez-Nino J (May 2005). “D-dimer concentrations in normal pregnancy: new diagnostic thresholds are needed”. Clinical chemistry 51 (5): 825-9. doi:10.1373/clinchem.2004.044883. PMID 15764641. http://www.clinchem.org/cgi/content/full/51/5/825.  ^ a b Gardner MD, Scott R (April 1980). “Age- and sex-related reference ranges for eight plasma constituents derived from randomly selected adults in a Scottish new town”. J. Clin. Pathol. 33 (4): 380-5. doi:10.1136/jcp.33.4.380. PMC 1146084. PMID 7400337. http://jcp.bmj.com/cgi/pmidlookup?view=long&pmid=7400337.  ^ a b c d Finney H, Newman DJ, Price CP (January 2000). “Adult reference ranges for serum cystatin C, creatinine and predicted creatinine clearance”. Ann. Clin. Biochem. 37 ( Pt 1): 49-59. doi:10.1258/0004563001901524. PMID 10672373. http://acb.rsmjournals.com/cgi/pmidlookup?view=long&pmid=10672373.  ^ a b c d e f g h Derived from molar values by multiplying with the molar mass of 113.118 g/mol, and divided by 10.000 to adapt from μg/L to mg/dL ^ a b MedlinePlus Encyclopedia Glucose tolerance test ^ a b c Derived from molar values using molar mass of 180g/mol ^ a b c d Derived from mass values using molar mass of 90.08 g/mol ^ a b Derived from mass values using molar mass of 88.06 g/mol ^ a b c d e f Derived from values in mg/dl to mmol/l, by dividing by 89, according to faqs.org: What are mg/dl and mmol/l? How to convert? Glucose? Cholesterol? Last Update July 21, 2009. Retrieved on July 21, 2009 ^ a b c d Derived from values in mg/dl to mmol/l, using molar mass of 386.65 g/mol ^ a b c Reference range (cholesterol) - GPnotebook ^ a b c d e f g h Royal College of Pathologists of Australasia; Cholesterol (HDL and LDL) - plasma or serum Last Updated: Monday, 6 August 2007 ^ a b c d e f g h i j Derived from values in mmol/l, using molar mass of 386.65 g/mol ^ What Your Cholesterol Levels Mean. American Heart Association. Retrieved on September 12, 2009 ^ American Association for Clinical Chemistry; HDL Cholesterol 健康診断 人間ドック 血液検査 尿検査 biochemical reference values - GPnotebook（英語） Values at lymphomation.org（英語） Descriptions at amarillomed.com（英語）