HIST4H4

HIST4H4爲人體中的一種編碼一類組蛋白H4的基因。HIST4H4沒有內含子，編碼組蛋白H4家族中的一種蛋白質。HIST4H4基因對應的mRNA缺乏Poly(A)尾巴。不過，這類mRNA有一個回文終止元件。 GRCh38: Ensembl release 89: ENSG00000197837 - Ensembl, May 2017 GRCm38: Ensembl release 89: ENSMUSG00000060639 - Ensembl, May 2017 Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.  Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.  Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ. The human and mouse replication-dependent histone genes. Genomics. Oct 2002, 80 (5): 487–98. PMID 12408966. doi:10.1016/S0888-7543(02)96850-3.  Entrez Gene: HIST4H4 histone cluster 4, H4. （原始内容存档于2019-10-17）.  Pauli U, Chrysogelos S, Stein G, et al. Protein-DNA interactions in vivo upstream of a cell cycle-regulated human H4 histone gene.. Science. 1987, 236 (4806): 1308–11. PMID 3035717. doi:10.1126/science.3035717.  Borowski P, Heiland M, Oehlmann K, et al. Non-structural protein 3 of hepatitis C virus inhibits phosphorylation mediated by cAMP-dependent protein kinase.. Eur. J. Biochem. 1996, 237 (3): 611–8. PMID 8647104. doi:10.1111/j.1432-1033.1996.0611p.x.  El Kharroubi A, Piras G, Zensen R, Martin MA. Transcriptional Activation of the Integrated Chromatin-Associated Human Immunodeficiency Virus Type 1 Promoter. Mol. Cell. Biol. 1998, 18 (5): 2535–44. PMC 110633 . PMID 9566873. doi:10.1128/mcb.18.5.2535.  Zhang Y, Sun ZW, Iratni R, et al. SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex. Mol. Cell. 1998, 1 (7): 1021–31. PMID 9651585. doi:10.1016/S1097-2765(00)80102-1.  Carrier F, Georgel PT, Pourquier P, et al. Gadd45, a p53-Responsive Stress Protein, Modifies DNA Accessibility on Damaged Chromatin. Mol. Cell. Biol. 1999, 19 (3): 1673–85. PMC 83961 . PMID 10022855.  Buggy JJ, Sideris ML, Mak P, et al. Cloning and characterization of a novel human histone deacetylase, HDAC8. Biochem. J. 2001,. 350 Pt 1 (Pt 1): 199–205. PMC 1221242 . PMID 10926844. doi:10.1042/0264-6021:3500199.  Deng L, de la Fuente C, Fu P, et al. Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones. Virology. 2001, 277 (2): 278–95. PMID 11080476. doi:10.1006/viro.2000.0593.  Chadwick BP, Willard HF. A Novel Chromatin Protein, Distantly Related to Histone H2a, Is Largely Excluded from the Inactive X Chromosome. J. Cell Biol. 2001, 152 (2): 375–84. PMC 2199617 . PMID 11266453. doi:10.1083/jcb.152.2.375.  Kovalsky O, Lung FD, Roller PP, Fornace AJ. Oligomerization of human Gadd45a protein. J. Biol. Chem. 2001, 276 (42): 39330–9. PMID 11498536. doi:10.1074/jbc.M105115200.  Deng L, Wang D, de la Fuente C, et al. Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA. Virology. 2001, 289 (2): 312–26. PMID 11689053. doi:10.1006/viro.2001.1129.  Lahn BT, Tang ZL, Zhou J, et al. Previously uncharacterized histone acetyltransferases implicated in mammalian spermatogenesis. Proc. Natl. Acad. Sci. U.S.A. 2002, 99 (13): 8707–12. PMC 124363 . PMID 12072557. doi:10.1073/pnas.082248899.  Ono S, Oue N, Kuniyasu H, et al. Acetylated histone H4 is reduced in human gastric adenomas and carcinomas. J. Exp. Clin. Cancer Res. 2003, 21 (3): 377–82. PMID 12385581.  Strausberg RL, Feingold EA, Grouse LH, et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. 2003, 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.  Kzhyshkowska J, Rusch A, Wolf H, Dobner T. Regulation of transcription by the heterogeneous nuclear ribonucleoprotein E1B-AP5 is mediated by complex formation with the novel bromodomain-containing protein BRD7. Biochem. J. 2003, 371 (Pt 2): 385–93. PMC 1223277 . PMID 12489984. doi:10.1042/BJ20021281.  Fujita K, Shimazaki N, Ohta Y, et al. Terminal deoxynucleotidyltransferase forms a ternary complex with a novel chromatin remodeling protein with 82 kDa and core histone. Genes Cells. 2004, 8 (6): 559–71. PMID 12786946. doi:10.1046/j.1365-2443.2003.00656.x.  Shiio Y, Eisenman RN. Histone sumoylation is associated with transcriptional repression. Proc. Natl. Acad. Sci. U.S.A. 2004, 100 (23): 13225–30. PMC 263760 . PMID 14578449. doi:10.1073/pnas.1735528100.  Coleman MA, Miller KA, Beernink PT, et al. Identification of chromatin-related protein interactions using protein microarrays. Proteomics. 2004, 3 (11): 2101–7. PMID 14595808. doi:10.1002/pmic.200300593.  Lusic M, Marcello A, Cereseto A, Giacca M. Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter. EMBO J. 2004, 22 (24): 6550–61. PMC 291826 . PMID 14657027. doi:10.1093/emboj/cdg631.  Kanno T, Kanno Y, Siegel RM, et al. Selective recognition of acetylated histones by bromodomain proteins visualized in living cells. Mol. Cell. 2004, 13 (1): 33–43. PMID 14731392. doi:10.1016/S1097-2765(03)00482-9.