组织蛋白酶H

组织蛋白酶H（英文：Cathepsin H）是一种在人体中由CTSH基因编码的蛋白质。 该基因编码的蛋白质是木瓜样蛋白酶（英语：Papain-like protease），一种溶酶体半胱氨酸蛋白酶，在溶酶体蛋白质的整体降解中很重要。它由二硫键连接的重链和轻链的二聚体组成，均由单一蛋白质前体产生。编码的蛋白质属于肽酶C1蛋白质家族，既可以作为氨肽酶（英语：Aminopeptidase），也可以作为内肽酶。该基因的表达增加与前列腺肿瘤的恶性进展有关。该基因已发现了编码不同蛋白异构体的两种转录变体。 與组织蛋白酶H相關的疾病；在維基數據上查看/編輯參考.  GRCh38: Ensembl release 89: ENSG00000103811 - Ensembl, May 2017 GRCm38: Ensembl release 89: ENSMUSG00000032359 - Ensembl, May 2017 Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.  Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.  Fuchs R, Machleidt W, Gassen HG. Molecular cloning and sequencing of a cDNA coding for mature human kidney cathepsin H. Biol Chem Hoppe-Seyler. Feb 1989, 369 (6): 469–75. PMID 2849458. doi:10.1515/bchm3.1988.369.1.469.  Entrez Gene: CTSH cathepsin H.  Sawicki G, Warwas M. Cathepsin H from human placenta.. Acta Biochim. Pol. 1990, 36 (3–4): 343–51. 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