黄体生成素β亚基

黄体生成素β亚基（英語：Luteinizing hormone subunit beta 或 lutropin subunit beta ）是一种由人类基因LHB 编码的蛋白质。 该基因位于19号染色体q13.3，编码黄体生成素的β亚基。而在马科动物中，黄体生成素的β亚基和绒毛膜促性腺激素的β亚基是由一个基因编码的。 Sairam MR, Li CH. Human pituitary lutropin. Isolation, properties, and the complete amino acid sequence of the beta-subunit. Biochim Biophys Acta. Feb 1976, 412 (1): 70–81. PMID 1191677.  Entrez Gene: LHB luteinizing hormone beta polypeptide.  Sherman GB, Wolfe MW, Farmerie TA, Clay CM, Threadgill DS, Sharp DC, Nilson JH. A single gene encodes the beta-subunits of equine luteinizing hormone and chorionic gonadotropin. Mol. Endocrinol. June 1992, 6 (6): 951–9. PMID 1379674. doi:10.1210/me.6.6.951.  Keutmann HT, Hua QX, Weiss MA. Structure of a receptor-binding fragment from human luteinizing hormone beta-subunit determined by [1H]- and [15N]nuclear magnetic resonance spectroscopy. Mol. Endocrinol. 1992, 6 (6): 904–13. PMID 1495492. doi:10.1210/me.6.6.904.  Weiss J, Axelrod L, Whitcomb RW; et al. 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Eutopic production of human chorionic gonadotropin beta (hCG beta) and luteinizing hormone beta (hLH beta) in the human testis. FEBS Lett. 1994, 343 (3): 229–33. PMID 7513655. doi:10.1016/0014-5793(94)80561-X.  引文格式1维护：显式使用等标签 (link) Keutmann HT, Rubin DA. A subunit interaction site in human luteinizing hormone: identification by photoaffinity cross-linking. Endocrinology. 1993, 132 (3): 1305–12. PMID 7679977. doi:10.1210/en.132.3.1305.  Herrlich A, Kühn B, Grosse R; et al. Involvement of Gs and Gi proteins in dual coupling of the luteinizing hormone receptor to adenylyl cyclase and phospholipase C. J. Biol. Chem. 1996, 271 (28): 16764–72. PMID 8663226. doi:10.1074/jbc.271.28.16764.  引文格式1维护：显式使用等标签 (link) Muyan M, Furuhashi M, Sugahara T, Boime I. The carboxy-terminal region of the beta-subunits of luteinizing hormone and chorionic gonadotropin differentially influence secretion and assembly of the heterodimers. Mol. Endocrinol. 1997, 10 (12): 1678–87. PMID 8961276. doi:10.1210/me.10.12.1678.  Roy AC, Liao WX, Chen Y; et al. Identification of seven novel mutations in LH beta-subunit gene by SSCP. Mol. Cell. Biochem. 1997, 165 (2): 151–3. PMID 8979264.  引文格式1维护：显式使用等标签 (link) Liao WX, Roy AC, Chan C; et al. A new molecular variant of luteinizing hormone associated with female infertility. Fertil. Steril. 1998, 69 (1): 102–6. PMID 9457942. doi:10.1016/S0015-0282(97)00445-7.  引文格式1维护：显式使用等标签 (link) O'Connor JF, Kovalevskaya G, Birken S; et al. The expression of the urinary forms of human luteinizing hormone beta fragment in various populations as assessed by a specific immunoradiometric assay. Hum. Reprod. 1998, 13 (4): 826–35. PMID 9619532. doi:10.1093/humrep/13.4.826.  引文格式1维护：显式使用等标签 (link) Takahashi K, Kurioka H, Ozaki T; et al. Increased prevalence of luteinizing hormone beta-subunit variant in Japanese infertility patients. Hum. Reprod. 1999, 13 (12): 3338–44. PMID 9886510. doi:10.1093/humrep/13.12.3338.  引文格式1维护：显式使用等标签 (link) Elter K, Erel CT, Cine N; et al. Role of the mutations Trp8 => Arg and Ile15 => Thr of the human luteinizing hormone beta-subunit in women with polycystic ovary syndrome. Fertil. Steril. 1999, 71 (3): 425–30. PMID 10065776. doi:10.1016/S0015-0282(98)00491-9.  引文格式1维护：显式使用等标签 (link) Jiang M, Pakarinen P, Zhang FP; et al. A common polymorphic allele of the human luteinizing hormone beta-subunit gene: additional mutations and differential function of the promoter sequence. Hum. Mol. Genet. 1999, 8 (11): 2037–46. PMID 10484773. doi:10.1093/hmg/8.11.2037.  引文格式1维护：显式使用等标签 (link)