傅嫈惠

傅嫈惠（1958年—）是臺灣臺中豐原出身的美国華裔生物学家和人类遗传学家，國立中興大學食品科學、俄亥俄州立大學畢業，目前是加州大学旧金山分校的神经学教授，美国国家科学院院士。 1980年取得国立中兴大学食品科学学位，1986年取得俄亥俄州立大学生物化学以及细胞生物学学位。之后，在俄亥俄州立大学和贝勒医学院从事了博士后研究，主要研究内容为人类基因组。她在业界工作过四年后，返回学术界担任犹他大学研究助理教授。2002年，在加州大学旧金山分校与合作者Louis Ptacek共同组建了实验室。 2018年，当选为美国国家科学院院士與中華民國中央研究院生命科學組院士。 Toh KL, Jones CR, He Y, Eide EJ, Hinz WA, Virshup DM, Ptáček LJ, Fu Y-H. An hPer2 phosphorylation site mutation in familial advanced sleep-phase syndrome. Science. 2001;291:1040-3. Xu Y, Padiath QS, Shapiro RE, Jones CR, Wu SC, Saigoh N, Saigoh K, Ptáček LJ, Fu Y-H. Functional consequences of a CKIδ mutation causing familial advanced sleep phase syndrome. Nature. 2005;434:640-4. Padiath QS, Saigoh K, Schiffman R, Asahara H, Koeppen A, Hogan K, Ptáček LJ, Fu Y-H. Lamin B1duplications cause autosomal dominant leukodystrophy. Nat Genet. 2006 Oct ; 38(10)1114-23. Epub 2006 Sep 3. He Y, Jones CR, Fujiki N, Xu Y, Guo B, Holder J, Nishino S, and Fu Y-H. Transcriptional suppressor DEC2 is a Regulator for Human Sleep Homeostasis. Science. 2009 325:866. Fu, YH and Marzluf, GA. cys-3, the positive-acting sulfur regulatory gene of Neurospora crassa, encodes a sequence-specific DNA-binding protein. J Biol Chem, 1990, 265, 11942-11947. Fu, Y.H., Kuhl, D.P., Pizzuti, et al. Variation of the CGG repeat at the fragile X site results in genetic instability: resolution of the Sherman paradox. Cell, 1991, 67, 1047-1058. Fu, Y.H., Pizzuti, A., Fenwick, R.G., Jr., et al. An unstable triplet repeat in a gene related to myotonic muscular dystrophy. Science, 1992, 255, 1256-1258. Yu, C.E., Oshima, J., Fu, Y.H., et al. Positional cloning of the Werner's syndrome gene （页面存档备份，存于互联网档案馆）. Science, 1996, 272, 258-262. Levy‑Lahad E, Wasco W, Poorkaj P, Romano DM, Oshima J, Pettingell WH, Yu C, Jondro PD, Schmidt SD, Wang K, Crowley AC, Fu Y-H, Guenette SY, Galas D, Nemens E, Wejsman EM, Bird TD, Schellenberg GD, Tanzi RE. Candidate gene for the chromosome 1 familial Alzheimer's disease locus. （页面存档备份，存于互联网档案馆） Science, 1995 269, 973-977. Xu Y, Toh KL, Jones CR, Shin JY, Fu Y-H*, Ptáček LJ. Modeling of a human circadian mutation yields insights into clock regulation by PER2 （页面存档备份，存于互联网档案馆）. Cell. 2007 Jan 12:128(1):59-70. Kaasik K, Kivimäe S, Allen JJ, Chalkley RJ, Huang Y, Baer K, Kissel H, Burlingame AL, Shokat KM, Ptáček LJ, Fu Y-H*. Glucose Sensor O-GlcNAcylation Coordinates with Phosphorylation to Regulate Circadian Clock.Cell Metab. 2013 Feb 5;17(2):291-302. Brennan KC, Bates EA, Shapiro RE, Zyuzin J, Hallows WC, Huang Y, Lee HY, Jones CR, Fu YH, Charles AC, Ptacek LJ. Casein kinase iδ Mutations in Familial Migraine and Advanced Sleep Phase （页面存档备份，存于互联网档案馆）.Science Transitional Mag. 2013 May 1; 183(5):183ra56. He Y, Jones CR, Fujiki N, Xu Y, Guo B, Holder J, Nishino S, and Fu Y-H. Transcriptional suppressor DEC2 is a Regulator for Human Sleep Homeostasis. Science. 2009 325:866. Kaasik K, Kivimäe S, Allen JJ, Chalkley RJ, Huang Y, Baer K, Kissel H, Burlingame AL, Shokat KM, Ptácek LJ, Fu YH. Glucose sensor O-GlcNAcylation coordinates with phosphorylation to regulate circadian clock. Cell Metab. 2013 Feb 5; 17(2):291-302. PMID 23395175; PMC 3597447. 睡眠的神经科学 傅嫈惠 (PDF). 國立中興大學秘書室 – National Chung Hsing University Secretariat Office. [2023-03-31]. （原始内容存档 (PDF)于2022-03-01）.  知识分子. 丹扬、傅嫈惠、高华健、林海帆、文小刚、张锋：新晋2018美国科学院院士. [2018-05-02]. （原始内容存档于2018-05-02）.  Official profile at University of California （页面存档备份，存于互联网档案馆） Official lab profile in collaboration with Louis Ptacek's lab at UCSF Fu's personal website （页面存档备份，存于互联网档案馆）