微RNA与微RNA靶数据库

小分子核糖核酸（microRNA，miRNA，微RNA）是一类由内源基因编码的长度约为22个核苷酸的非编码单链RNA 分子,它们在动植物中参与转录后基因表达调控.。microRNA (微RNA)参与各种各样的生物学过程，包括凋亡、增殖、分化和细胞周期。此外，microRNA(微RNA)还与肿瘤和其他疾病的发生和发展相关。这里收集了目前比较流行的microRNA（微RNA）基因及其靶基因数据库，以便大家使用和查询. Bartel, DP. MicroRNAs: target recognition and regulatory functions. Cell. 2009, 136 (2): 215–33. PMID 19167326. doi:10.1016/j.cell.2009.01.002.  Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets.. Cell. 2005, 120 (1): 15–20. PMID 15652477. doi:10.1016/j.cell.2004.12.035.  Yang JH, Li JH, Shao P, Zhou H, Chen YQ, Qu LH. starBase: a database for exploring microRNA–mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data.. Nucl. Acids Res. 2010, (Database issue): 1–8. PMID 21037263. doi:10.1093/nar/gkq1056.  Krek A, Grün D, Poy MN, Wolf R, Rosenberg L, Epstein EJ, MacMenamin P, da Piedade I, Gunsalus KC, Stoffel M, Rajewsky N. Combinatorial microRNA target predictions.. Nat Genet. 2005, 37 (5): 495–500. PMID 15806104. doi:10.1038/ng1536.  Kertesz M, Iovino N, Unnerstall U, Gaul U, Segal E. The role of site accessibility in microRNA target recognition.. Nat Genet. 2007, 39 (10): 1278–84. PMID 17893677. doi:10.1038/ng2135.  Miranda KC, Huynh T, Tay Y, Ang YS, Tam WL, Thomson AM, Lim B, Rigoutsos I. A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes.. Cell. 2006, 126 (6): 1203–17. PMID 16990141. doi:10.1016/j.cell.2006.07.031.  Xiao F, Zuo Z, Cai G, Kang S, Gao X, Li T. miRecords: an integrated resource for microRNA-target interactions.. Nucl. Acids Res. 2009, 37 (Database issue): D105–110. PMID 18996891. doi:10.1093/nar/gkn851.  Sethupathy P, Corda B, Hatzigeorgiou AG. TarBase: A comprehensive database of experimentally supported animal microRNA targets.. RNA. 2006, 12 (2): 192–197. PMID 16373484. doi:10.1261/rna.2239606.  Hsu SD, Lin FM, Wu WY, Liang C, Huang WC, Chan WL, Tsai WT, Chen GZ, Lee CJ, Chiu CM, Chien CH, Wu MC, Huang CY, Tsou AP, Huang HD. miRTarBase: a database curates experimentally validated microRNA-target interactions.. Nucleic acids research. 2010, 39 (Database issue): D163–169. PMID 21071411. doi:10.1093/nar/gkq1107.  Yang JH, Shao P, Zhou H, Chen YQ, Qu LH. deepBase: a database for deeply annotating and mining deep sequencing data.. Nucl. Acids Res. 2010, 38 (Database issue): D123–130. PMC 2808990 . PMID 19966272. doi:10.1093/nar/gkp943.  Griffiths-Jones S, Saini HK, van Dongen S, Enright AJ. miRBase: tools for microRNA genomics.. Nucl. Acids Res. 2008, 36: D154–D158. PMC 2238936 . PMID 17991681. doi:10.1093/nar/gkm952.  Betel D, Wilson M, Gabow A, Marks DS, Sander C. The microRNA.org resource: targets and expression.. Nucl. Acids Res. 2007, 36 (Database issue): D149–153. PMC 2238905 . PMID 18158296. doi:10.1093/nar/gkm995.  Megraw M, Sethupathy P, Corda B, Hatzigeorgiou AG. miRGen: a database for the study of animal microRNA genomic organization and function.. Nucl. Acids Res. 2007, 35 (Database issue): D149–55. PMC 1669779 . PMID 17108354. doi:10.1093/nar/gkl904.  Hsu PW, Huang HD, Hsu SD, Lin LZ, Tsou AP, Tseng CP, Stadler PF, Washietl S, Hofacker IL. miRNAMap: genomic maps of microRNA genes and their target genes in mammalian genomes.. Nucl. Acids Res. 2006, 34 (Database issue): D135–139. PMC 1347497 . PMID 16381831. doi:10.1093/nar/gkj135.  Zhang Z, Yu J, Li D, Zhang Z, Liu F, Zhou X, Wang T, Ling Y, Su Z. PMRD: plant microRNA database.. Nucl. Acids Res. 2010, 38 (Database issue): D806–813. PMC 2808885 . PMID 19808935. doi:10.1093/nar/gkp818.  Lee, RC; Ambros V. An extensive class of small RNAs in Caenorhabditis elegans. Science. 2001, 294 (5543): 862–864. PMID 11679672. doi:10.1126/science.1065329.  引文使用过时参数coauthors (帮助) Ambros, V. microRNAs: tiny regulators with great potential. Cell. 2001, 107 (7): 823–826. PMID 11779458. doi:10.1016/S0092-8674(01)00616-X.  miRBase database （页面存档备份，存于互联网档案馆） deepBase database starBase database targetScan （页面存档备份，存于互联网档案馆） picTar miRecords database