心脏肥大

心脏肥大（英語：Cardiomegaly），有时稱大心脏或簡稱心肥大，是一种心脏扩大的疾病。它通常是因為某些因素而使心脏更加用力跳動而造成的的结果，例如肥胖、心脏瓣膜疾病、高血压和冠状动脉疾病。心肌病也与心脏肥大有关。 心脏肥大可能很严重，具体取决于心脏扩大的部位，并可能导致充血性心力衰竭。最近的研究表明，心脏肥大与更高的心源性猝死风险相关。心衰竭随着年龄的增长而增加，男性比女性更常见，非洲裔美国人比其他种族更常见。根据一些研究，被诊断患有心力衰竭的人中有一半在被诊断出后五年内死亡。 心脏肥大可能会随着时间的推移而改善，但许多心脏扩大（扩张型心肌病）的人需要终生接受药物治疗。有一个患有或患有心脏肥大的直系亲属可能表明一个人更容易患上这种疾病。 Enlarged heart. Heart and Stroke Foundation of Canada. [2019-03-29]. （原始内容存档于2019-03-29）. Types...Hypertrophic cardiomyopathy, Left ventricular hypertrophy (LVH), Intense, prolonged athletic training  Hershberger, Ray E; Morales, Ana; Siegfried, Jill D. Clinical and genetic issues in dilated cardiomyopathy: A review for genetics professionals. Genetics in Medicine. 22 September 2010, 12 (11): 655–667. PMC 3118426 . PMID 20864896. doi:10.1097/GIM.0b013e3181f2481f.  Luk, A; Ahn, E; Soor, G S; Butany, J. Dilated cardiomyopathy: a review. Journal of Clinical Pathology. 18 November 2008, 62 (3): 219–225. PMID 19017683. S2CID 28182534. doi:10.1136/jcp.2008.060731.  What Is an Enlarged Heart (Cardiomegaly)?. WebMD. 2019-01-30 [2019-03-29]. （原始内容存档于2022-03-24）.  Lee, Ji Eun; Oh, Jin-Hee; Lee, Jae Young; Koh, Dae Kyun. Massive Cardiomegaly due to Dilated Cardiomyopathy Causing Bronchial Obstruction in an Infant. Journal of Cardiovascular Ultrasound. 2014, 22 (2): 84–7. PMC 4096670 . PMID 25031799. doi:10.4250/jcu.2014.22.2.84.  Marian, Ali J.; Braunwald, Eugene. Hypertrophic Cardiomyopathy. Circulation Research. 15 September 2017, 121 (7): 749–770. PMC 5654557 . PMID 28912181. doi:10.1161/CIRCRESAHA.117.311059.  Maron, Martin S. Clinical Utility of Cardiovascular Magnetic Resonance in Hypertrophic Cardiomyopathy. Journal of Cardiovascular Magnetic Resonance. 1 February 2012, 14 (1): 13. PMC 3293092 . PMID 22296938. doi:10.1186/1532-429X-14-13.  Almog, C; Weissberg, D; Herczeg, E; Pajewski, M. Thymolipoma simulating cardiomegaly: a clinicopathological rarity.. Thorax. 1 February 1977, 32 (1): 116–120. PMC 470537 . PMID 138960. doi:10.1136/thx.32.1.116.  Hou, Jianglong; Kang, Y. James. Regression of pathological cardiac hypertrophy: Signaling pathways and therapeutic targets. Pharmacology & Therapeutics. September 2012, 135 (3): 337–354. PMC 3458709 . PMID 22750195. doi:10.1016/j.pharmthera.2012.06.006.  Luis Fuentes, Virginia; Wilkie, Lois J. Asymptomatic Hypertrophic Cardiomyopathy (PDF). Veterinary Clinics of North America: Small Animal Practice. September 2017, 47 (5): 1041–1054 [2022-05-07]. PMID 28662873. doi:10.1016/j.cvsm.2017.05.002. （原始内容 (PDF)存档于2021-01-22）.  Maron, Barry J; Maron, Martin S. Hypertrophic cardiomyopathy. The Lancet. January 2013, 381 (9862): 242–255. PMID 22874472. S2CID 38333896. doi:10.1016/S0140-6736(12)60397-3.  Overview of Cardiomyopathies. The Lecturio Medical Concept Library. [25 August 2021]. （原始内容存档于2022-05-01）.  Tavora F; et al. Cardiomegaly is a common arrhythmogenic substrate in adult sudden cardiac deaths and is associated with obesity.. Pathology. 2012, 44 (3): 187–91. PMID 22406485. S2CID 25422195. doi:10.1097/PAT.0b013e3283513f54.  Warner, Jennifer. Heart Failure Patients Too Optimistic. WebMD. [2022-03-17]. （原始内容存档于2022-06-23） （英语）.  Enlarged heart - Symptoms and causes. mayoclinic.org. [19 March 2018]. （原始内容存档于2016-12-02）.  美国心脏协会 （页面存档备份，存于互联网档案馆） 探究问题的核心：了解心脏肥大的原因 （页面存档备份，存于互联网档案馆）（简体中文） 医学主题