C-Myc

C-Myc或Myc是编码转录因子的调节基因。这一基因编码的蛋白在细胞核内被磷酸化，有多种功能：在细胞周期进程、细胞凋亡和细胞轉化中发挥作用。 Myc可与以下蛋白质发生交互作用： ACTL6A BRCA1 Bcl-2 Cyclin T1 CHD8 DNMT3A EP400 GTF2I HTATIP let-7 MAPK1 MAPK8 MAX MLH1 MYCBP2 MYCBP NMI NFYB NFYC P73 PCAF PFDN5 RuvB-like 1 SAP130 SMAD2 SMAD3 SMARCA4 SMARCB1 SUPT3H TIAM1 TADA2L TAF9 TBX3 TFAP2A TRRAP WDR5 YY1 ZBTB17. GRCh38: Ensembl release 89: ENSG00000136997 - Ensembl, May 2017 GRCm38: Ensembl release 89: ENSMUSG00000022346 - Ensembl, May 2017 Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.  Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.  Myc myelocytomatosis oncogene [ Mus musculus (house mouse) ]. [2018-03-02]. （原始内容存档于2019-05-11）.  Park J, Wood MA, Cole MD. BAF53 forms distinct nuclear complexes and functions as a critical c-Myc-interacting nuclear cofactor for oncogenic transformation. Molecular and Cellular Biology. March 2002, 22 (5): 1307–16. 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