生长激素受体

生长激素受体（英語：Growth hormone receptor)是一种由人类基因GHR 编码的蛋白质，GHR的直系同源物广泛存在于各种哺乳动物中。 此基因编码的蛋白是结合生长激素的跨膜受体。 生长激素受体能与SGTA、PTPN11、JAK激酶2、SOCS1和CISH发生交互作用。 GHR 基因曾作为动物核DNA（英语：nuclear DNA）系统发育标记，对其10号外显子基因多态性的探究第一次阐释了啮齿目主要类群间的亲缘关系。GHR也用于较低阶元的分类，在鼠总科、八齿鼠科、田鼠亞科、鼠亚科（英语：Murinae）、白足鼠屬等啮齿动物，及熊型總科、猫科等肉食动物以及皮翼目的分类上有重要作用。GHR的9号内含子也用于阐释鼬科、鬣狗科的系统发生。 Entrez Gene: GHR growth hormone receptor.  OrthoMaM phylogenetic marker: GHR coding sequence. [2014-02-04]. （原始内容存档于2015-09-24）.  Schantl, Julia A; Roza Marcel, De Jong Ad P, Strous Ger J. Small glutamine-rich tetratricopeptide repeat-containing protein (SGT) interacts with the ubiquitin-dependent endocytosis (UbE) motif of the growth hormone receptor. Biochem. J. (England). August 2003, 373 (Pt 3): 855–63. ISSN 0264-6021. PMC 1223544 . PMID 12735788. doi:10.1042/BJ20021591.  引文使用过时参数coauthors (帮助) Stofega, M R; Herrington J, Billestrup N, Carter-Su C. 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PMID 16503281. doi:10.1016/j.ympev.2005.10.017.  醫學主題詞表（MeSH）：Somatotropin+receptors Illustration at nih.gov （页面存档备份，存于互联网档案馆） Overview （页面存档备份，存于互联网档案馆） Growth Hormone Receptor （页面存档备份，存于互联网档案馆）: Molecule of the Month by Shuchismita Dutta and David Goodsell (April 2004)