TATA结合蛋白

TATA结合蛋白质（英語：TATA-binding protein，TBP）是一种通用转录因子，具体结合于DNA序列上的TATA盒。TATA盒位于真核基因的转录起始位点上游约25个bp，属于啟動子区。TBP可以和各个TBP相关因子共同组成通用转录因子TFIID,再进一步组成RNA聚合酶Ⅱ的转录起始复合物。 TATA结合蛋白与下列蛋白質进行互作： BRF1, BTAF1, C-Fos, C-jun, EDF1, GTF2B (TFIIB), GTF2A1 (TFIIA subunit 1), GTF2F1 (TFIIF subunit 1) GTF2H4 (TFIIH subunit 4), Mdm2, MSX1, NFYB, P53, PAX6, POLR2A, POU2F1, RELA, NR2B1, TAF1, TAF4, TAF5, TAF6, TAF7, TAF9. TAF10, TAF11, TAF13, TAF15. 與TATA结合蛋白相關的疾病；在維基數據上查看/編輯參考.  GRCh38: Ensembl release 89: ENSG00000112592 - Ensembl, May 2017 GRCm38: Ensembl release 89: ENSMUSG00000014767 - Ensembl, May 2017 Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.  Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.  The molecular basis of eukaryotic transcription. Proc. Natl. Acad. Sci. U.S.A. 2007, 104 (32): 12955–61. PMC 1941834 . 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PMID 8663456. doi:10.1074/jbc.271.30.18194.  GeneReviews/NCBI/国家卫生研究院/大学进入脊髓小脑失调类型17（页面存档备份，存于互联网档案馆） 交互式TBP结构在梅西。ac.新西兰 每月PDB分子主題TATA-binding protein 醫學主題詞表（MeSH）：TATA-Box+Binding+Protein FactorBook TBP