腎皮質壞死

腎皮質壞死(Renal cortical necrosis、RCN，瀰漫性雙側腎皮質壞死(diffuse bilateral renal cortical necrosis、BRCN)、，瀰漫性皮質壞死(diffuse cortical necrosis)、急性皮質壞死(acute cortical necrosis)、急性皮質壞死急性腎功能衰竭(acute renal failure with acute cortical necrosis))是急性腎功能衰竭的一種罕見病症。該病症"通常通過顯著減少腎動脈灌注(Perfusion)繼發於血管痙攣、微血管損傷，或彌散性血管內凝血"，以及由急性腎小管壞死的病理進展所致。經常伴隨著產科病症發生、諸如胎盤早剝(Placental abruption)及敗血性休克，而且是三倍多見於發展中國家與工業化國家中(佔急性腎損傷的病因2％-6％)。 妊娠相關(病例>50％)。 胎盤早剝(Placental abruption)。 感染流產。 長期胎死宮內(Prolonged intrauterine fetal death)。 重度子癇。 HIV 蛇咬傷 暴飲 休克 創傷 鐮刀型紅血球疾病 紅斑性狼瘡(SLE) 敗血症 SLE相關抗磷脂综合征 維生素缺乏症 胰腺炎 疟疾 腦膜炎球菌病(Meningococcemia) 藥物引起的中毒(比如NSAIDs、造影劑(Contrast Media)、奎寧、或ATRA) 先天性心臟缺損(Congenital heart disease) 患者需要以透析來彌補其腎臟的功能。 皮質壞死是一種嚴重的危及生命的病症，且死亡率超過50％。 Deverajan, Prasad. Langman, Craig B , 编. eMedicine: Renal Cortical Necrosis. Medscape. May 26, 2011 [27 March 2012]. （原始内容存档于2021-08-29）.  Bakshsish Singh, Ankur Gupta, Sandeep Mahajan, Ruchika Gupta. 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