I tried and I get the same error.

I'm not sure I understand, the problem is that the formula tries to install the module in `/usr/local/Cellar/mackup/0.5.9/lib/python2.7/site-packages/` while `PYTHONPATH` contains `/usr/local/lib/python2.7/site-packages`.

`python setup.py install` should take care of creating the folder no ?