Well, there's already a space between <input> and <label>, so definitely a new line there.

As for inside the label, I'd do it as much as you can (without introducing spaces), so together it's: 

    <input type="radio" value="open" name="publication-access-{{_id}}" id="publication-access-open-{{_id}}" {{#if open}}checked="checked"{{/if}} /> 
      <label for="publication-access-open-{{_id}}"><i class="icon-public"></i> 
        Open Access<span class="description">Everyone has access to the publication.</span>
      </label><br/>

That's already much easier to read for me and see what's going on when I get to style it. Again, this was just a thought for the future. The design I do on this requires me to place the input inside the label so I restructure things anyway. In the end (after my branch is merged) it will look something like this:

            <label class="selection {{#if public}}selected{{/if}}" for="annotation-access-public-{{_id}}">
              <input type="radio" value="public" name="annotation-access-{{_id}}" id="annotation-access-public-{{_id}}" {{#if public}}checked="checked"{{/if}} />
              <i class="icon-closed"></i> Public
            </label>