With the siSPOTR tools you can:      Identify candidate siRNA/shRNA sequences for your gene of interest with a low potential for off-targeting.     Evaluate the off-targeting potential for any RNAi sequence.     View a list of all predicted off-targets for siRNA candidates, along with information on the site-type composition and probability of being off-targeted.     BLAST your sequence to search for siRNA-like on/off-targeting