added clone methd to bedregion and a bedstreamer object
Added/updated extend and subtract - testing new streamer
streams can't seek
gzip_reader needed a fileobj arg
moved from bedfile to bedstreamer
removed bedfile private call (debug code)
added support for scrambled (circular) junctions and retained introns
memoize shouldn't be used when running tests
added Poisson functions
updated poisson docs
added export for testing, which will disable memoize
added llh code for PWM and potential variant calling
need to revcomp mapped reads
modified intron retension to keep 5' and 3' extensions.
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doc
alter exon calling to work with new GTF object (ensembl annotations)
no need to re-open GTF
should include splice site for retained introns
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