v0.019

    Refactor to add a initial target step.
    Create location specified gibson design commands.
primer3 notes
accept primer melting temp as options
accept multiple primer3 options on command line, gc percentage, primer size and melting temp
add tm values to primer3 conf test
    Added option to set Primer3 config values by command line for: 
        - melting temp
        - gc percentage
        - primer size