Bio::BIORUBY_EXTRA_VERSION set to ".5000" (unstable version).
Renamed RELEASE_NOTES.rdoc to doc/RELEASE_NOTES-1.4.3.rdoc
New RELEASE_NOTES.rdoc for the next release version.
ChangeLog updated: add log about 1.4.3 release.
renamed ChangeLog to doc/ChangeLog-1.4.3
Rakefile: Update hardcoded git tag name for updating of ChangeLog.
Refresh ChangeLog, showing changes after 1.4.3 release.

 * Refresh to the new ChangeLog, showing changes after 1.4.3 release.
   For the changes before 1.4.3, see doc/ChangeLog-1.4.3.
   For the changes before 1.4.2, see doc/ChangeLog-before-1.4.2.
   For the changes before 1.3.1, see doc/ChangeLog-before-1.3.1.
Remove obsolete Bio::DBGET

 * Remove Bio::DBGET because it uses old original protocol that was
   discontinued about 8 years ago.
 * Remove lib/bio/io/dbget.rb and sample/dbget.
Remove Bio::Ensembl because it does not work

 * Remove Bio::Ensembl because it does not work after the renewal of
   the Ensembl web site in 2008.
 * Alternative is io-ensembl gem which supports current Ensembl API.
   http://rubygems.org/gems/bio-ensembl
 * Deleted files: lib/bio/io/ensembl.rb,
   test/network/bio/io/test_ensembl.rb, test/unit/bio/io/test_ensembl.rb.
Remove issues about removed classes Bio::Ensembl and Bio::DBGET.
regenerate bioruby.gemspec with rake regemspec
Remove Bio::NCBI::SOAP which is broken

 * Remove Bio::NCBI::SOAP in lib/bio/io/ncbisoap.rb, because it always
   raises error during the parsing of WSDL files provided by NCBI, both
   with Ruby 1.8.X (with bundled SOAP4R) and Ruby 1.9.X (with
   soap4r-ruby1.9 gem). To solve the error, modifying SOAP4R may be
   needed, that seems very difficult. The alternative is Bio::NCBI::REST,
   REST client class for the NCBI EUtil web services.
Remove Bio::KEGG::Taxonomy which is old and broken

 * Remove Bio::KEGG::Taxonomy because it raises error or the data
   structure in the return value seems to be broken. In addition,
   running the sample script sample/demo_kegg_taxonomy.rb shows
   error or falls into infinite loop. Moreover, KEGG closes public
   FTP site and the target data file of the class ("taxonomy")
   can only be obtained by paid subscribers. From the above reasons,
   it seems there are no users of this class now.
 * Deleted files: lib/bio/db/kegg/taxonomy.rb,
   sample/demo_kegg_taxonomy.rb
Remove issues about removed classes Bio::NCBI::SOAP and Bio::KEGG::Taxonomy
Remove Bio::Shell#ncbisoap which uses removed Bio::NCBI::SOAP.
regenerate bioruby.gemspec with rake regemspec
Delete autoload lines of removed classes.
Delete autoload line of a removed class Bio::NCBI::SOAP.
Remove Bio.method_missing because it is broken.

 * Bio.method_missing, the hook of undefined methods, providing
   shortcut of Bio::Shell methods, is now removed, because it does
   not work correctly, and because the use of method_missing should
   normally be avoided unless it is really necessary. Alternatively,
   use Bio::Shell.xxxxx (xxxxx is a method name).
environment variable TESTOPTS=-v for verbose output of rake test