Maybe it would be worth testing whether an un-unrolled version would be noticeably smaller in generated bytes:

    /* 3. Mix. */
    for (i = 0; i < 64; ++i) {
        RNDr(S, W, i, ks[i]); 
    }

with `ks` being defined just above the function like:

    static const uint32_t ks[64] = {
        0x428a2f98, 0x71374491, 0xb5c0fbcf, 0xe9b5dba5,
        0x3956c25b, 0x59f111f1, 0x923f82a4, 0xab1c5ed5,
        0xd807aa98, 0x12835b01, 0x243185be, 0x550c7dc3,
        0x72be5d74, 0x80deb1fe, 0x9bdc06a7, 0xc19bf174,
        0xe49b69c1, 0xefbe4786, 0x0fc19dc6, 0x240ca1cc,
        0x2de92c6f, 0x4a7484aa, 0x5cb0a9dc, 0x76f988da,
        0x983e5152, 0xa831c66d, 0xb00327c8, 0xbf597fc7,
        0xc6e00bf3, 0xd5a79147, 0x06ca6351, 0x14292967,
        0x27b70a85, 0x2e1b2138, 0x4d2c6dfc, 0x53380d13,
        0x650a7354, 0x766a0abb, 0x81c2c92e, 0x92722c85,
        0xa2bfe8a1, 0xa81a664b, 0xc24b8b70, 0xc76c51a3,
        0xd192e819, 0xd6990624, 0xf40e3585, 0x106aa070,
        0x19a4c116, 0x1e376c08, 0x2748774c, 0x34b0bcb5,
        0x391c0cb3, 0x4ed8aa4a, 0x5b9cca4f, 0x682e6ff3,
        0x748f82ee, 0x78a5636f, 0x84c87814, 0x8cc70208,
        0x90befffa, 0xa4506ceb, 0xbef9a3f7, 0xc67178f2,
    };