Menopause (phase where the ovaries stop producing eggs and estrogen), perimenopause (begins before menopause where the production of estrogen reduces gradually) or hysterectomy (removal of the uterus) produces symptoms that cause uneasiness. The symptoms include mood swings, extreme tiredness, irritability, hot flushes, itchy eyes or irregular bleeding. A 3 month dosage of Amberen is known to alleviate these symptoms as it has been clinically tested under supervision of researchers.