Pesticide

context: Pesticides are substances meant for attracting, seducing, and then destroying any pest. They are a class of biocide. The most common use of pesticides is as plant protection products (also known as crop protection products), which in general protect plants from damaging influences such as weeds, fungi, or insects. This use of pesticides is so common that the term pesticide is often treated as synonymous with plant protection product, although it is in fact a broader term, as pesticides are also used for non-agricultural purposes. The term pesticide includes all of the following: herbicide, insecticide, insect growth regulator, nematicide, termiticide, molluscicide, piscicide, avicide, rodenticide, predacide, bactericide, insect repellent, animal repellent, antimicrobial, fungicide, disinfectant (antimicrobial), and sanitizer.

context: In general, a pesticide is a chemical or biological agent (such as a virus, bacterium, antimicrobial, or disinfectant) that deters, incapacitates, kills, or otherwise discourages pests. Target pests can include insects, plant pathogens, weeds, mollusks, birds, mammals, fish, nematodes (roundworms), and microbes that destroy property, cause nuisance, or spread disease, or are disease vectors. Although pesticides have benefits, some also have drawbacks, such as potential toxicity to humans and other species. According to the Stockholm Convention on Persistent Organic Pollutants, 9 of the 12 most dangerous and persistent organic chemicals are organochlorine pesticides.

context: Pesticides can be classified by target organism (e.g., herbicides, insecticides, fungicides, rodenticides, and pediculicides - see table), chemical structure (e.g., organic, inorganic, synthetic, or biological (biopesticide), although the distinction can sometimes blur), and physical state (e.g. gaseous (fumigant)). Biopesticides include microbial pesticides and biochemical pesticides. Plant-derived pesticides, or "botanicals", have been developing quickly. These include the pyrethroids, rotenoids, nicotinoids, and a fourth group that includes strychnine and scilliroside.:15

context: Many pesticides can be grouped into chemical families. Prominent insecticide families include organochlorines, organophosphates, and carbamates. Organochlorine hydrocarbons (e.g., DDT) could be separated into dichlorodiphenylethanes, cyclodiene compounds, and other related compounds. They operate by disrupting the sodium/potassium balance of the nerve fiber, forcing the nerve to transmit continuously. Their toxicities vary greatly, but they have been phased out because of their persistence and potential to bioaccumulate.:239–240 Organophosphate and carbamates largely replaced organochlorines. Both operate through inhibiting the enzyme acetylcholinesterase, allowing acetylcholine to transfer nerve impulses indefinitely and causing a variety of symptoms such as weakness or paralysis. Organophosphates are quite toxic to vertebrates, and have in some cases been replaced by less toxic carbamates.:136–137 Thiocarbamate and dithiocarbamates are subclasses of carbamates. Prominent families of herbicides include phenoxy and benzoic acid herbicides (e.g. 2,4-D), triazines (e.g., atrazine), ureas (e.g., diuron), and Chloroacetanilides (e.g., alachlor). Phenoxy compounds tend to selectively kill broad-leaf weeds rather than grasses. The phenoxy and benzoic acid herbicides function similar to plant growth hormones, and grow cells without normal cell division, crushing the plant's nutrient transport system.:300 Triazines interfere with photosynthesis.:335 Many commonly used pesticides are not included in these families, including glyphosate.

context: Pesticides can be classified based upon their biological mechanism function or application method. Most pesticides work by poisoning pests. A systemic pesticide moves inside a plant following absorption by the plant. With insecticides and most fungicides, this movement is usually upward (through the xylem) and outward. Increased efficiency may be a result. Systemic insecticides, which poison pollen and nectar in the flowers[citation needed], may kill bees and other needed pollinators[citation needed].

context: Pesticides are used to control organisms that are considered to be harmful. For example, they are used to kill mosquitoes that can transmit potentially deadly diseases like West Nile virus, yellow fever, and malaria. They can also kill bees, wasps or ants that can cause allergic reactions. Insecticides can protect animals from illnesses that can be caused by parasites such as fleas. Pesticides can prevent sickness in humans that could be caused by moldy food or diseased produce. Herbicides can be used to clear roadside weeds, trees and brush. They can also kill invasive weeds that may cause environmental damage. Herbicides are commonly applied in ponds and lakes to control algae and plants such as water grasses that can interfere with activities like swimming and fishing and cause the water to look or smell unpleasant. Uncontrolled pests such as termites and mold can damage structures such as houses. Pesticides are used in grocery stores and food storage facilities to manage rodents and insects that infest food such as grain. Each use of a pesticide carries some associated risk. Proper pesticide use decreases these associated risks to a level deemed acceptable by pesticide regulatory agencies such as the United States Environmental Protection Agency (EPA) and the Pest Management Regulatory Agency (PMRA) of Canada.

context: DDT, sprayed on the walls of houses, is an organochlorine that has been used to fight malaria since the 1950s. Recent policy statements by the World Health Organization have given stronger support to this approach. However, DDT and other organochlorine pesticides have been banned in most countries worldwide because of their persistence in the environment and human toxicity. DDT use is not always effective, as resistance to DDT was identified in Africa as early as 1955, and by 1972 nineteen species of mosquito worldwide were resistant to DDT.

context: In 2006 and 2007, the world used approximately 2.4 megatonnes (5.3×109 lb) of pesticides, with herbicides constituting the biggest part of the world pesticide use at 40%, followed by insecticides (17%) and fungicides (10%). In 2006 and 2007 the U.S. used approximately 0.5 megatonnes (1.1×109 lb) of pesticides, accounting for 22% of the world total, including 857 million pounds (389 kt) of conventional pesticides, which are used in the agricultural sector (80% of conventional pesticide use) as well as the industrial, commercial, governmental and home & garden sectors.Pesticides are also found in majority of U.S. households with 78 million out of the 105.5 million households indicating that they use some form of pesticide. As of 2007, there were more than 1,055 active ingredients registered as pesticides, which yield over 20,000 pesticide products that are marketed in the United States.

context: Every dollar ($1) that is spent on pesticides for crops yields four dollars ($4) in crops saved. This means based that, on the amount of money spent per year on pesticides, $10 billion, there is an additional $40 billion savings in crop that would be lost due to damage by insects and weeds. In general, farmers benefit from having an increase in crop yield and from being able to grow a variety of crops throughout the year. Consumers of agricultural products also benefit from being able to afford the vast quantities of produce available year-round. The general public also benefits from the use of pesticides for the control of insect-borne diseases and illnesses, such as malaria. The use of pesticides creates a large job market within the agrichemical sector.

context: Pesticides may cause acute and delayed health effects in people who are exposed. Pesticide exposure can cause a variety of adverse health effects, ranging from simple irritation of the skin and eyes to more severe effects such as affecting the nervous system, mimicking hormones causing reproductive problems, and also causing cancer. A 2007 systematic review found that "most studies on non-Hodgkin lymphoma and leukemia showed positive associations with pesticide exposure" and thus concluded that cosmetic use of pesticides should be decreased. There is substantial evidence of associations between organophosphate insecticide exposures and neurobehavioral alterations.  Limited evidence also exists for other negative outcomes from pesticide exposure including neurological, birth defects, fetal death,

context: The World Health Organization and the UN Environment Programme estimate that each year, 3 million workers in agriculture in the developing world experience severe poisoning from pesticides, about 18,000 of whom die. Owing to inadequate regulation and safety precautions, 99% of pesticide related deaths occur in developing countries that account for only 25% of pesticide usage. According to one study, as many as 25 million workers in developing countries may suffer mild pesticide poisoning yearly. There are several careers aside from agriculture that may also put individuals at risk of health effects from pesticide exposure including pet groomers, groundskeepers, and fumigators.

context: Pesticide use raises a number of environmental concerns. Over 98% of sprayed insecticides and 95% of herbicides reach a destination other than their target species, including non-target species, air, water and soil. Pesticide drift occurs when pesticides suspended in the air as particles are carried by wind to other areas, potentially contaminating them. Pesticides are one of the causes of water pollution, and some pesticides are persistent organic pollutants and contribute to soil contamination.

context: Since chlorinated hydrocarbon pesticides dissolve in fats and are not excreted, organisms tend to retain them almost indefinitely. Biological magnification is the process whereby these chlorinated hydrocarbons (pesticides) are more concentrated at each level of the food chain. Among marine animals, pesticide concentrations are higher in carnivorous fishes, and even more so in the fish-eating birds and mammals at the top of the ecological pyramid. Global distillation is the process whereby pesticides are transported from warmer to colder regions of the Earth, in particular the Poles and mountain tops. Pesticides that evaporate into the atmosphere at relatively high temperature can be carried considerable distances (thousands of kilometers) by the wind to an area of lower temperature, where they condense and are carried back to the ground in rain or snow.

context: In order to reduce negative impacts, it is desirable that pesticides be degradable or at least quickly deactivated in the environment. Such loss of activity or toxicity of pesticides is due to both innate chemical properties of the compounds and environmental processes or conditions. For example, the presence of halogens within a chemical structure often slows down degradation in an aerobic environment. Adsorption to soil may retard pesticide movement, but also may reduce bioavailability to microbial degraders.

context: Alternatives to pesticides are available and include methods of cultivation, use of biological pest controls (such as pheromones and microbial pesticides), genetic engineering, and methods of interfering with insect breeding. Application of composted yard waste has also been used as a way of controlling pests. These methods are becoming increasingly popular and often are safer than traditional chemical pesticides. In addition, EPA is registering reduced-risk conventional pesticides in increasing numbers.

context: The term "push-pull" was established in 1987 as an approach for integrated pest management (IPM). This strategy uses a mixture of behavior-modifying stimuli to manipulate the distribution and abundance of insects. "Push" means the insects are repelled or deterred away from whatever resource that is being protected. "Pull" means that certain stimuli (semiochemical stimuli, pheromones, food additives, visual stimuli, genetically altered plants, etc.) are used to attract pests to trap crops where they will be killed. There are numerous different components involved in order to implement a Push-Pull Strategy in IPM.

context: Some evidence shows that alternatives to pesticides can be equally effective as the use of chemicals. For example, Sweden has halved its use of pesticides with hardly any reduction in crops.[unreliable source?] In Indonesia, farmers have reduced pesticide use on rice fields by 65% and experienced a 15% crop increase.[unreliable source?] A study of Maize fields in northern Florida found that the application of composted yard waste with high carbon to nitrogen ratio to agricultural fields was highly effective at reducing the population of plant-parasitic nematodes and increasing crop yield, with yield increases ranging from 10% to 212%; the observed effects were long-term, often not appearing until the third season of the study.

context: Pesticides are often referred to according to the type of pest they control. Pesticides can also be considered as either biodegradable pesticides, which will be broken down by microbes and other living beings into harmless compounds, or persistent pesticides, which may take months or years before they are broken down: it was the persistence of DDT, for example, which led to its accumulation in the food chain and its killing of birds of prey at the top of the food chain. Another way to think about pesticides is to consider those that are chemical pesticides or are derived from a common source or production method.

context: The following sulfonylureas have been commercialized for weed control: amidosulfuron, azimsulfuron, bensulfuron-methyl, chlorimuron-ethyl, ethoxysulfuron, flazasulfuron, flupyrsulfuron-methyl-sodium, halosulfuron-methyl, imazosulfuron, nicosulfuron, oxasulfuron, primisulfuron-methyl, pyrazosulfuron-ethyl, rimsulfuron, sulfometuron-methyl Sulfosulfuron, terbacil, bispyribac-sodium, cyclosulfamuron, and pyrithiobac-sodium. Nicosulfuron, triflusulfuron methyl, and chlorsulfuron are broad-spectrum herbicides that kill plants by inhibiting the enzyme acetolactate synthase. In the 1960s, more than 1 kg/ha (0.89 lb/acre) crop protection chemical was typically applied, while sulfonylureates allow as little as 1% as much material to achieve the same effect.

context: Though pesticide regulations differ from country to country, pesticides, and products on which they were used are traded across international borders. To deal with inconsistencies in regulations among countries, delegates to a conference of the United Nations Food and Agriculture Organization adopted an International Code of Conduct on the Distribution and Use of Pesticides in 1985 to create voluntary standards of pesticide regulation for different countries. The Code was updated in 1998 and 2002. The FAO claims that the code has raised awareness about pesticide hazards and decreased the number of countries without restrictions on pesticide use.

context: Three other efforts to improve regulation of international pesticide trade are the United Nations London Guidelines for the Exchange of Information on Chemicals in International Trade and the United Nations Codex Alimentarius Commission.[citation needed] The former seeks to implement procedures for ensuring that prior informed consent exists between countries buying and selling pesticides, while the latter seeks to create uniform standards for maximum levels of pesticide residues among participating countries. Both initiatives operate on a voluntary basis.

context: Pesticides safety education and pesticide applicator regulation are designed to protect the public from pesticide misuse, but do not eliminate all misuse. Reducing the use of pesticides and choosing less toxic pesticides may reduce risks placed on society and the environment from pesticide use. Integrated pest management, the use of multiple approaches to control pests, is becoming widespread and has been used with success in countries such as Indonesia, China, Bangladesh, the U.S., Australia, and Mexico. IPM attempts to recognize the more widespread impacts of an action on an ecosystem, so that natural balances are not upset. New pesticides are being developed, including biological and botanical derivatives and alternatives that are thought to reduce health and environmental risks. In addition, applicators are being encouraged to consider alternative controls and adopt methods that reduce the use of chemical pesticides.

context: In the United States, the Environmental Protection Agency (EPA) is responsible for regulating pesticides under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Food Quality Protection Act (FQPA). Studies must be conducted to establish the conditions in which the material is safe to use and the effectiveness against the intended pest(s). The EPA regulates pesticides to ensure that these products do not pose adverse effects to humans or the environment. Pesticides produced before November 1984 continue to be reassessed in order to meet the current scientific and regulatory standards. All registered pesticides are reviewed every 15 years to ensure they meet the proper standards. During the registration process, a label is created. The label contains directions for proper use of the material in addition to safety restrictions. Based on acute toxicity, pesticides are assigned to a Toxicity Class.

context: Some pesticides are considered too hazardous for sale to the general public and are designated restricted use pesticides. Only certified applicators, who have passed an exam, may purchase or supervise the application of restricted use pesticides. Records of sales and use are required to be maintained and may be audited by government agencies charged with the enforcement of pesticide regulations. These records must be made available to employees and state or territorial environmental regulatory agencies.

context: Since before 2000 BC, humans have utilized pesticides to protect their crops. The first known pesticide was elemental sulfur dusting used in ancient Sumer about 4,500 years ago in ancient Mesopotamia. The Rig Veda, which is about 4,000 years old, mentions the use of poisonous plants for pest control. By the 15th century, toxic chemicals such as arsenic, mercury, and lead were being applied to crops to kill pests. In the 17th century, nicotine sulfate was extracted from tobacco leaves for use as an insecticide. The 19th century saw the introduction of two more natural pesticides, pyrethrum, which is derived from chrysanthemums, and rotenone, which is derived from the roots of tropical vegetables. Until the 1950s, arsenic-based pesticides were dominant. Paul Müller discovered that DDT was a very effective insecticide. Organochlorines such as DDT were dominant, but they were replaced in the U.S. by organophosphates and carbamates by 1975. Since then, pyrethrin compounds have become the dominant insecticide. Herbicides became common in the 1960s, led by "triazine and other nitrogen-based compounds, carboxylic acids such as 2,4-dichlorophenoxyacetic acid, and glyphosate".

context: The first legislation providing federal authority for regulating pesticides was enacted in 1910; however, decades later during the 1940s manufacturers began to produce large amounts of synthetic pesticides and their use became widespread. Some sources consider the 1940s and 1950s to have been the start of the "pesticide era." Although the U.S. Environmental Protection Agency was established in 1970 and amendments to the pesticide law in 1972, pesticide use has increased 50-fold since 1950 and 2.3 million tonnes (2.5 million short tons) of industrial pesticides are now[when?] used each year. Seventy-five percent of all pesticides in the world are used in developed countries, but use in developing countries is increasing. A study of USA pesticide use trends through 1997 was published in 2003 by the National Science Foundation's Center for Integrated Pest Management.