Title: Kinase inhibitors :
Authors: Kuster, Bernhard.
Date: 2011
Publisher: Humana Press/Springer,
Physical description: xi, 256 p. : ill. (some col.) ; 27 cm.
Language: English
LC classification: Q
Contents: Targeting Cancer with Small-Molecular-Weight Kinase Inhibitors / Doriano Fabbro, Sandra W. Cowan-Jacob, Henrik Möbitz, and Georg Martiny-Baron -- Small-Molecule Protein and Lipid Kinase Inhibitors in Inflammation and Specific Models for Their Evaluation / Matthias Gaestel and Alexey Kotlyarov -- Measuring the Activity of Leucine-Rich Repeat Kinase 2: A Kinase Involved in Parkinson’s Disease / Byoung Dae Lee, Xiaojie Li, Ted M. Dawson, and Valina L. Dawson -- Measuring PI3K Lipid Kinase Activity -- Elisa Ciraolo, Alessia Perino, and Emilio Hirsch -- A Fluorescence Polarization Assay for the Discovery of Inhibitors of the Polo-Box Domain of Polo-Like Kinase / Wolfgang Reindl, Klaus Strebhardt, and Thorsten Berg. Assessment of Hepatotoxicity Potential of Drug Candidate Molecules Including Kinase Inhibitors by Hepatocyte Imaging Assay Technology and Bile Flux Imaging Assay Technology / Jinghai J. Xu, Margaret C. Dunn, Arthur R. Smith, and Eric S. Tien -- Kinase Inhibitor Selectivity Profiling Using Differential Scanning Fluorimetry / Oleg Fedorov, Frank H. Niesen, and Stefan Knapp -- Chemoproteomic Characterization of Protein Kinase Inhibitors Using Immobilized ATP / James S. Duncan, Timothy A.J. Haystead, and David W. Litchfield -- Proteome-Wide Identification of Staurosporine-Binding Kinases Using Capture Compound Mass Spectrometry / Jenny J. Fischer, Olivia Y. Graebner (neé Baessler), and Mathias Dreger -- Affinity Purification of Proteins Binding to Kinase Inhibitors Immobilized on Self-Assembling Monolayers / Marcus Bantscheff, Scott Hobson, and Bernhard Kuster. Kinase Inhibitor Profiling Using Chemoproteomics / Markus Schirle, Eugene C. Petrella, Scott M. Brittain, David Schwalb, Edmund Harrington, Ivan Cornella-Taracido, and John A. Tallarico -- Covalent Cross-Linking of Kinases with Their Corresponding Peptide Substrates / Alexander V. Statsuk and Kevan M. Shokat -- Receptor Tyrosine Kinase Inhibitor Profiling Using Bead-Based Multiplex Sandwich Immunoassays / Oliver Pötz, Nicole Schneiderhan-Marra, Tanja Henzler, Thomas Herget, and Thomas O. Joos -- Monitoring Phosphoproteomic Response to Targeted Kinase Inhibitors Using Reverse-Phase Protein Microarrays / Gabriela Lavezzari and Mark R. Lackner -- Measuring Phosphorylation-Specific Changes in Response to Kinase Inhibitors in Mammalian Cells Using Quantitative Proteomics / Nurhan Özlü, Marc Kirchner, and Judith Jebanathirajah Steen. Investigation of Acquired Resistance to EGFR-Targeted Therapies in Lung Cancer Using cDNA Microarrays / Kian Kani, Rafaella Sordella, and Parag Mallick.
Subject headings (LCSH): Protein kinases--Inhibitors