Title: Carbohydrate-based drug discovery /
Authors: Wong, Chi-Huey.
Date: 2003
Publisher: Wiley-VCH,
Physical description: 2 volumes (xxxii, 947 pages) : illustrations (some color) ; 25 cm
Language: English
LC classification: R
Contents: Synthetic methodologies / Chikako Saotome, Osamu Kanie -- Complex carbohydrate synthesis / Makoto Kiso, Hideharu Ishida, Hiromune Ando -- The chemistry of sialic acid / Geert-Jan Boons, Alexei V. Demchenko -- Solid-phase oligosaccharide synthesis / Peter H. Seeberger -- Solution and polymer-supported synthesis of carbohydrates / Shin-Ichiro Nishimura -- Enzymatic synthesis of oligosaccharides / Jianbo Zhang, Jun Shao, Prezemk Kowal, Peng George Wang -- Glycopeptides and glycoproteins : synthetic chemistry and biology / Oliver Seitz -- Synthesis of complex carbohydrates : Everninomicin 13,384-1 / K.C. Nicolaou, Helen J. Mitchell, Scott A. Snyder -- Chemical synthesis of asparagine-linked glycoprotein oligosaccharides : recent examples / Yukishige Ito, Ichiro Matsuo -- Chemistry and biochemistry of asparagine-linked protein glycosylation / Barbara Imperiali, Vincent W.-F. Tai --^ Conformational analysis of C-glycosides and related compounds : programming conformational profiles of C- and O-glycosides / Peter G. Goekjian, Alexander Wei, Yoshito Kishi -- Synthetic lipid A antagonists for sepsis treatment / William J. Christ, Lynn D. Hawkins, Michael D. Lewis, Yoshito Kishi -- Polysialic acid vaccines / Harold J. Jennings -- Synthetic carbohydrate-based vaccines / Stacy J. Keding, Samuel J. Danishefsky -- Chemistry, biochemistry, and pharmaceutical potentials of glycosaminoglycans and related saccharides / Tasneem Islam, Robert J. Linhardt -- A new generation of antithrombotics based on synthetic oligosaccharides / Maurice Petitou, Jean-Marc Herbert -- Sequencing of oligosaccharides and glycoproteins / Stuart M. Haslam, Kay-Hooi Khoo, Anne Dell --^ Preparation of heterocyclic 2-deoxystreptamine aminoglycoside analogues and characterization of their interaction with RNAs by use of electrospray ionization mass spectrometry / Richard H. Griffey, Steven A. Hofstadler, Eric E. Swayze -- Glycosylation analysis of a recombinant P-selectin antagonist by high-pH anion-exchange chromatography with pulsed electrochemical detection (HPAEC/PED) / Mark R. Hardy, Richard J. Cornell -- Analytical techniques for the characterization and sequencing of glycosaminoglycans / Ram Sasisekharan, Zachary Shriver, Mallik Sundaram, Ganesh Venkataraman -- Thermodynamic models of the multivalency effect / Pavel I. Kitov, David R. Bundle -- Synthetic multivalent carbohydrate ligands as effectors or inhibitors of biological processes / Laura L. Kiessling, Jason K. Pontrello, Michael C. Schuster -- Glycosyltransferase inhibitors / Karl-Heinz Jung, Richard R. Schmidt -- RNA-aminoglycoside interactions / Haim Weizman, Yitzhak Tor --^ Glycosylated natural products / Jon S. Thorson, Thomas Vogt -- Novel enzymatic mechanisms in the biosynthesis of unusual sugars / Alexander Wong, Xuemei He, Hung-Wen Liu -- Neoglycolipids : identification of functional carbohydrate epitopes / Ten Feizi, Alexander M. Lawson, Wengang Chai -- A preamble to aglycone reconstruction for membrane-presented glycolipid mimics / Murugesapillai Mylvaganam, Clifford A. Lingwood -- Small molecule inhibitors of the sulfotransferases / Dawn E. Verdugo, Lars C. Pedersen, Carolyn R. Bertozzi -- Carbohydrate-based treatment of cancer metastasis / Reiji Kannagi -- N-acetylneuraminic acid derivatives and mimetics as anti-influenza agents / Robin Thomson, Mark Von Itzstein -- Modified and modifying sugars as a new tool for the development of therapeutic agents : the biochemically engineered N-acyl side chain of sialic acid : biological implications and possible uses in medicine / Rüdiger Horstkorte, Oliver T. Keppler, Werner Reutter --^ Modified and modifying sugars as a new tool for the development of therapeutic agents : glycosidated phospholipids as a new type of antiproliferative agents / Kerstin Danker, Annette Fischer, Werner Reutter -- Glycoside primers and inhibitors of glycosylation / Jillian R. Brown, Mark M. Fuster, Jeffrey D. Esko -- Carbohydrate-based drug discovery in the battle against bacterial infections : new opportunities arising from programmable one-pot oligosaccharide synthesis / Thomas K. Ritter, Prof. Dr. Chi-Huey Wong.
Subject headings (LCSH): Carbohydrate drugs.; Carbohydrates--Synthesis.; Carbohydrates.; Glycoconjugates--Physiological effect.