Title: Epidemiological aspects of cutaneous malignant melanoma /
Authors: Gallagher, R. P.; Elwood, J. Mark.
Date: 1994
Publisher: Kluwer Academic Publishers,
Physical description: xiii, 329 pages : illustrations, maps ; 25 cm.
Language: English
LC classification: R
Abstract: Significant progress has been made in recent years in understanding the origins of cutaneous malignant melanoma. Knowledge of the relationship between solar radiation and melanoma has undergone profound change and it now appears that both the character and timing of exposure may be more important than total cumulative dose in accounting for risk. The melanoma-sunlight model currently emerging from this research may prove an instructive heuristic exercise for environmental epidemiology; as we currently tend to restrict ourselves to searches for uniform total dose response relationships between cancers and suspected environmental carcinogens. The study of the relationship between acquired melanocytic nevi and melanoma which began about 15 years ago has led to useful new information about predictors of melanoma risk, and in addition has opened new perspectives on the development of nevi in children. Definition of the factors for nevus development in children may lead to the possibility of primary prevention programs for melanoma in younger generations of children. Recent new evidence has surfaced suggesting that certain occupational groups, including electrical and electronic workers as well as chemists and petroleum refinery workers may be at elevated risk of melanoma. These leads should be vigorously pursued. A great deal of work is going into the study of ways of screening high risk populations in order to detect melanoma at its earliest stages when current treatment protocols are most effective. The visibility of lesions on the skin challenges classical definitions of early detection and screening in epidemiology. These important studies on malignant melanoma are gathered in Epidemiological Aspects of Cutaneous Malignant Melanoma, which will prove to be a relevant and valuable source for people involved in the field.
Contents: 1. Recent progress in the epidemiology of malignant melanoma / Richard P. Gallagher and J. Mark Elwood -- 2. Sun exposure and the epidemiology of malignant melanoma / J. Mark Elwood and Richard P. Gallagher -- 3. Etiological clues from the anatomical distribution of cutaneous melanoma / Adele Green and Robert MacLennan -- 4. Tables of ambient solar ultraviolet radiation for use in epidemiological studies of malignant melanoma / Brian L. Diffey and J. Mark Elwood -- 5. Non-solar sources of ultraviolet radiation and cutaneous malignant melanoma: a review of the evidence / Loraine D. Marrett -- 6. Risk factors for prevalence of nevi: a review / Leslie K. Dennis and Emily White -- 7. The atypical mole syndrome - a definition of phenotype / Julia A. Newton and Veronique Bataille -- 8. Risk of cutaneous melanoma by number of melanocytic nevi and correlation of nevi by anatomic site / Elizabeth A. Holly, John W. Kelly, David K. Ahn, Steven N. Shpall and Judith I. Rosen. 9. Malignant melanoma of the skin in the telecommunications industry / Louise De Guire -- 10. Petroleum refinery exposure and risk of malignant melanoma / Margaret M. Hornstra, Mark J. Klan and Dan S. Sharp -- 11. Methods for evaluating confounding and effect modification in a small occupational study of cutaneous malignant melanoma / Judith A. Schwartzbaum, R. Woodrow Setzer and Lawrence L. Kupper -- 12. Melanoma and pregnancy / Elizabeth A. Holly and Rosemary D. Cress -- 13. Cutaneous melanoma and oral contraceptives / Elizabeth A. Holly -- 14. Epidemiology of diet and melanoma incidence - a brief review / Constance S. Kirkpatrick -- 15. Dietary and other correlates of melanoma in Hawaii: preliminary findings / Loic Le Marchand, Jean H. Hankin, Laurence N. Kolonel and Lynne R. Wilkens -- 16. Early detection and lethal melanoma in Connecticut: a preliminary analysis / Marianne Berwick, Neil Dubin, George Roush and Raymond Barnhill. 17. Risk factors for presentation with thick primary melanoma include older age, male sex, smoking, and may include occupation in certain industries / Peter Hersey, Timothy Strong, Duncan Grant and Zinny Marish -- 18. Skin cancer screening in Massachusetts: the program and methodologic questions / Howard K. Koh, Donald R. Miller, Alan C. Geller and Robert A. Lew -- 19. The epidemiology of melanoma: where do we go from here? / Bruce K. Armstrong.
Subject headings (LCSH): Melanoma--Epidemiology.