Vetsupply: The Big 5 Protection Pack is an advanced treatment for dogs. It protects your dog in and out. The bundle packs protects against wide range of external as well as internal parasites. The oral treatment controls heartworms, fleas, paralysis ticks, and intestinal worms including tapeworms in dogs. Monthly dose safeguards your dogs against various types of parasites. It is safe for dogs and puppies above 8 weeks of age.