CREATE TABLE "table1_2453243_5" (
  "no_in_series" text,
  "no_in_season" text,
  "title" text,
  "directed_by" text,
  "written_by" text,
  "original_air_date" text,
  "production_code" text
);

Question: What is the title of the episode with production code 406?
SQL: SELECT "title" FROM "table1_2453243_5" WHERE "production_code"='406';

Question: Who write episode number 48 in the series?
SQL: SELECT "written_by" FROM "table1_2453243_5" WHERE "no_in_series"='48';