Patent ID: 11561187

Abstract:
An in vitro method for detecting presence of cancer includes obtaining a single hair sample. An x-ray beam is emitted from a source towards the hair sample. A small angle X-ray scattering (SAXS) intensity profile is generated after the x-ray beam hits the hair sample. The SAXS profile is received on a detector to obtain SAXS data, which is desmeared and Kratky Analysis is performed. A relative estimation of peak area under 1.38 nm−1 to 0.89 nm−1 from keratin and lipid content in the hair sample is performed to obtain R and is corrected by dividing by D, thickness of the hair. R′ is computed using formula: 10×R2/(D−R). The value of R′ is compared with clinically validated samples. If R′ value is below 0.7, it indicates the presence of cancer and if it is above 0.8, it indicates absence of cancer.