Patent ID: 10745334

Abstract:
The disclosure discloses a method for synthesizing 2,3,5,6-tetrafluoro-4-methoxymethyl benzyl alcohol from 1,4-bis(methoxymethyl)-2,3,5,6-tetrafluorobenzene, belongings to the technical field of organic synthesis. 1,4-bis(methoxymethyl)-2,3,5,6-tetrafluorobenzene reacts in mixed solution consisting of sulfuric acid aqueous solution and organic carboxylic acid, the obtained mixture is subjected to ester group hydrolysis reaction in the presence of an inorganic base and then to hydroxyl methylation reaction, 2,3,5,6-tetrafluoro-4-methoxymethyl benzyl alcohol is finally obtained via separation and purification, and 1,4-bis(methoxymethyl)-2,3,5,6-tetrafluorobenzene is recovered. The disclosure not only realizes the resource utilization of low-value 1,4-bis(methoxymethyl)-2,3,5,6-tetrafluorobenzene, and meanwhile has the advantages of mild reaction conditions, simple operation, high synthesis yield, good product quality and the like. The disclosure has high social and economic values.