Patent ID: 11786535

Abstract:
A method of inhibiting cyclooxygenase includes administering an inhibitory agent to a patient in need thereof. The inhibitory agent is selected from Compound 1 (5-{[(4-fluorobenzyl)(tetrahydrofuran-2-ylmethyl)amino]methyl}-2-methoxyphenyl)methanol), Compound 2 (N-{[3-(3-methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methyl}-N-methyl-2-(1H-pyrazol-4-yl)ethanamine), Compound 3 ({4-[3-(2-pyridinyl)benzyl]-3-morpholinyl}acetic acid), and Compound 4 ([4-chloro-2-(7-oxo-5,6,7,8-tetrahydro-1H-pyrazole[4,3-g]quinoline-5-yl)phenoxy]acetic acid). Compounds 1-4 may inhibit both the COX-1 and the COX-2 enzymes.