Patent ID: 12005227

Abstract:
A dopamine or drug/therapeutics delivery and monitoring system for treatment of brain disease having an implantable titrator connected to the brain, a microtube for delivery of dopamine, a second microtube for withdrawal of CSF, a micropump for controlled pumping of dopamine into the brain responsive to sensed dopamine levels in the withdrawn CSF and a mixing chamber in the implantable titrator to combine withdrawn CSF with dopamine from a reservoir in the titrator to form a mixture for controlled delivery of the mixture. The system may have a fiber optic implanted and dopamine sensor responsive to certain sensed wavelengths of light received by a microcontroller. The system further has a dopamine reservoir and a carbon fiber resistance probe and may use fast scan cyclic voltammetry. A needle memory alloy having a straight and curved phase can be deployed into a blood vessel of a vascular system for trans-vascular delivery.