Patent ID: 11180370

Abstract:
A method of manufacturing the calcium nanohydroxyapatite Ca10(PO4)6(OH)2 structurally modified with Li+ ions (nHAP:Li+) Li0.1Ca9.9(PO4)6(OH)2 optionally doped with 1-2% mol of Eu3+ cations in the form of nanocrystalline powder and use of Li0.1Ca9.9(PO4)6(OH)2 in regenerative medicine as an agent improving of proliferative activity of progenitor cells and demonstrating an anti-apoptotic effect on progenitor cells and in addition use of Li0.1Ca9.9(PO4)6(OH)2 doped with 1-2% mol Eu3+ cations as an agent improving of proliferative activity of progenitor cells and demonstrating the luminescence signal used in diagnostic application.