Patent ID: 10918275

Abstract:
Optical texture analysis of the inner retina, including the retinal nerve fiber layer (RNFL), ganglion cell layer (GCL), or inner plexiform layer (IPL), or a combination of these layers, can be used to detect and quantify RNFL/GCL/IPL abnormalities. From a set of scans of a retina, anterior and posterior boundaries of an inner retinal layer of interest can be determined. Optical density measurements at specific locations on the retina and depths within the layer of interest can be extracted from the scans. From these measurements, a set of optical texture signature values corresponding to different locations can be computed, where the optical texture signature value for a given location provides information about a tissue composition of the inner retinal layer at that location. The texture signature values can provide a topographical map of a retinal layer, which can facilitate detection and quantification of abnormalities.