Patent ID: 10914851

Abstract:
Time of flight (TOF) corrections for radiation detector elements of a TOF positron emission tomography (TOF PET) scanner are generated by solving an over-determined set of equations defined by calibration data acquired by the TOF PET scanner from a point source located at an isocenter of the TOF PET scanner, suitably represented as matrix equation at Δt=CS where Δt represents TOF time differences, C is a relational matrix encoding the radiation detector elements, and S represents the TOF corrections. A pseudo-inverse C−1 of relational matrix C may be computed to solve S=C−1 Δt. TOF corrections can be generated for a particular type of detector unit by identifying the radiation detector elements in C by detector unit. Further, multi-photon triggering time stamps can be adjusted to first-photon triggering based on √{square root over (P1/Pm)} where P1 is average photon count using first-photon triggering and Pm is a photon count using multi-photon triggering.