Patent ID: 10905691

Abstract:
A method for treatment of a bacterial infection in a host mammal in need of such treatment or a method of administering to the host mammal an effective amount of a Triazolo(4,5-d)pyrimidine of formula(I): wherein R1 is C3-5 alkyl optionally substituted by one or more halogen atoms; R2 is a phenyl group, optionally substituted by one or more halogen atoms; R3 and R4 are both hydroxyl; R is XOH, wherein X is CH2, OCH2CH2, or a bond, and wherein when X is a bond, R is OH; or a pharmaceutical acceptable salt, provided that when X is CH2 or a bond, R1 is not propyl; when X is CH2 and R1 is CH2CH2CF3, butyl or pentyl, the phenyl group at R2 must be substituted by fluorine; when X is OCH2CH2 and R1 is propyl, the phenyl group at R2 must be substituted by fluorine.