Patent ID: 11299463

Abstract:
In one aspect the invention relates to the use of an amine compound in a process for the manufacture of a fluorinated or non-fluorinated 5- or 6-membered heterocyclic compound containing two nitrogen atoms in the ring system of the said compound, preferably of pyrazoles or pyrimidones. The invention also relates to a process for the manufacture of pyrazoles or pyrimidones, which may be fluorinated or may not be fluorinated (non-fluorinated). Especially, the invention relates to process for the manufacture of fluorinated pyrazoles or pyrimidones, and in particular the invention relates to process for the manufacture of such fluorinated pyrazoles or pyrimidones, which each are very important building blocks for pharmaceutical and agro-applications. For example, the fungicides are Bixafen, Fluxapyroxad, Fluindapyr, Sedaxane, Isopyrazam and Benzovindifupyr strongly depend on such fluorinated pyrazoles as key building blocks, or for Florasulam and Clorasulam-methyl (Diclosulam), respectively.