Radioactive decay
The most troublesome transuranic elements in spent fuel are neptunium-237 (half-life two million years) and plutonium-239 (half-life 24,000 years). Consequently, high-level radioactive waste requires sophisticated treatment and management to successfully isolate it from the biosphere. This usually necessitates treatment, followed by a long-term management strategy involving permanent storage, disposal or transformation of the waste into a non-toxic form. Radioactive decay follows the half-life rule, which means that the rate of decay is inversely proportional to the duration of decay. In other words, the radiation from a long-lived isotope like iodine-129 will be much less intense than that of short-lived isotope like iodine-131.