The End of Evangelion
In "The End of Evangelion", after Rei rejects Gendo's attempt to initiate his version of Instrumentality using the grafted embryonic Adam, Rei and the absorbed embryo merge with Lilith. The resultant being, taking the form of a giant winged Rei, generates a massive anti-AT field that nullifies the AT fields of all humans, reverting them to a primordial soup.