日米和親条約
US Commodore Matthew Perry arrived on June 3, 1853, on a mission to force a treaty opening Japan to trade. Ieyoshi died on July 27, 1853, before the treaty could be concluded, of heart failure possibly brought on by heat stroke, and was succeeded by his third son Tokugawa Iesada. The following year the Tokugawa shogunate was forced to accept the American demands by signing the Convention of Kanagawa.