Anne of France
Anne of France (or Anne de Beaujeu; 3 April 146114 November 1522) was a French princess and regent, the eldest daughter of Louis XI by Charlotte of Savoy. Anne was the sister of Charles VIII, for whom she acted as regent during his minority from 1483 until 1491. During the regency she was one of the most powerful women of late fifteenth-century Europe, and was referred to as "Madame la Grande". Between 1503 and 1521, she also acted as de facto regent of the Duchy of Bourbon during the reign of her daughter Suzanne, Duchess of Bourbon.