Third Mithridatic War
Following the 69 BCE defeat of Tigranes' army in the Third Mithridatic War against Roman troops led by Lucius Licinius Lucullus, Antiochus XIII Asiaticus nominally restored the Seleucid rule over the region. However, as a client king thanks to Lucullus' approval he apparently did not wield any actual power over Tyre. Lucullus' successor Pompey had Antiochus assassinated and thus ended the Seleucid dynasty for good.