Uíge Province
Beginning in October 2004 and continuing into 2005, Uíge Province was the centre of an outbreak of Marburg hemorrhagic fever, a disease closely related to Ebola. It was caused by Marburg virus which is an African RNA virus that causes green monkey disease. Now thought to be under control, there were 374 cases with 88% deaths. According to the United Nations, it was, at the time, the world's worst epidemic of any kind of hemorrhagic fever.