Teimuraz I of Kakheti
Darejan was a daughter of Teimuraz I of Kakheti and his second wife Khorashan, a sister of the neighboring Georgian monarch, Luarsab II of Kartli. In 1623, Teimuraz married off Darejan to his influential vassal, Zurab, Duke of Aragvi, in spite of the protests from Queen Khorashan, who blamed Zurab's family for many misfortunes that had befallen on her native Kartli. The marriage secured Zurab's support to Teimuraz against the warlord Giorgi Saakadze, in 1626, although Saakadze was himself married to Zurab's sister. Rid of Saakadze, Teimuraz then instigated Zurab to assassinate the rival pro-Persian ruler Simon II of Kartli in 1630, but he soon began to suspect Zurab of regal ambitions. Teimuraz invited his son-in-law to dinner and had him beheaded. He then sent Zurab's severed head to the Persian shah Safi to prove his loyalty and to maintain his innocence in Simon II's death.