Battle of Marj Dabiq
Leaving Al-Ashraf Tuman bay II the Vizier, in charge, Al-Ashraf Qansuh al-Ghuri marched against the Ottoman Turks. He was defeated by Selim I at the Battle of Marj Dabiq, north of Aleppo, on 24 August 1516; the betrayal of two Mamluk leaders Janbirdi al-Ghazali and Khayr Baig led to the Mamluk defeat and to the death of the Sultan Qansuh. This marked the end of Mamluk control of the Middle East that eventually passed to the Ottomans. Al-Ashraf Qansuh al-Ghuri himself fell upon the field and his head was carried to the Conqueror.