DNA virus
The effect of "Wolbachia" infection on virus replication in insect hosts is complex and depends on the "Wolbachia" strain and virus species. While several studies have indicated consistent refractory phenotypes of "Wolbachia" infection on positive-sense RNA viruses in "Drosophila melanogaster", the yellow fever mosquito "Aedes aegypti" and the Asian tiger mosquito "Aedes albopictus". This effect is not seen in DNA virus infection and in some cases "Wolbachia" infection has been associated or shown to increase single stranded DNA and double-stranded DNA virus infection. There is also currently no evidence that "Wolbachia" infection restricts any tested negative-sense RNA viruses indicating "Wolbachia" would be unsuitable for restriction of negative-sense RNA arthropod borne viruses.