Listeria monocytogenes
Intracellular bacteria, "Listeria monocytogenes", have been shown to stimulate host immune response through STING. STING may play an important role in the production of MCP-1 and CCL7 chemokines. STING deficient monocytes are intrinsically defective in migration to the liver during "Listeria monocytogenes" infection. In this way, STING protects host from "Listeria monocytogenes" infection by regulating monocyte migration. The activation of STING is likely to be mediated by cyclic-di-AMP secreted by intracellular bacteria.