Edinson Cavani
At the end of the season, Insigne returned to Napoli, choosing the number 24 jersey. On 16 September 2012, he scored his first goal in Serie A, after entering as a substitute for Edinson Cavani in a 3–1 home win over Parma. Four days later, he made his debut in UEFA club competitions, starting in a 4–0 win against Swedish side AIK Fotboll in the UEFA Europa League.