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Barzin conducted concerts with soloists including Emanuel Feuermann (cello), Ossip Gabrilowitsch (piano), Mischa Elman and Joseph Szigeti (violin), Myra Hess, Rudolf Serkin (piano) and Artie Shaw (clarinet). He also developed radio programs on WNYC and WQXR and guest conducted the Minneapolis Symphony Orchestra, the Saint Louis Symphony Orchestra, and the NBC Symphony Orchestra.