北里柴三郎
Early 1887, in Bonn, Behring had found that the serum of tetanus-immune white rats contained a substance that neutralized anthrax bacilli. He recognized this as the source of their “resistance”. On 4 December 1890, Behring and Kitasato Shibasaburō published their first paper on blood-serum therapy. On 11 December, another report, signed by Behring, discussed blood-serum therapy not only in the treatment of tetanus, but also in diphtheria.