Shar Pei
Affected Shar Pei have an elevated level of interleukin 6, and this leads to an accumulation of acute phase proteins in the body during the fevers. The acute phase proteins are broken down to form type AA amyloid, which deposits in the kidneys and less so in the liver, spleen, and gastrointestinal tract. This eventually leads to kidney or liver failure by the age of six years.