Orihime Inoue
Luppi is introduced midway through the Arrancar Arc, and serves as a minor villain and character foil to Grimmjow. He replaces the disgraced Grimmjow as 6th Espada, and along with Grimmjow, Yammy, and Wonderweiss, is sent to attack Karakura Town. Luppi fights the Soul Reapers there, and holds the upper hand until he is frozen solid by Tōshirō Hitsugaya, at which point he is forced to retreat to Hueco Mundo. On his return, Luppi is shocked to learn that his assault was merely a distraction from the abduction of Orihime Inoue. Orihime then demonstrates her healing powers to the gathered arrancars by restoring Grimmjow Jaegerjaquez's amputated arm, and Grimmjow murders Luppi to regain his Espada rank. But during the second Wandenreich invasion months later, Luppi is revived by Mayuri to assist him in his fight against Giselle.