禽流感
Ancestral reconstruction is not limited to biological traits. Spatial location is also a trait, and ancestral reconstruction methods can infer the locations of ancestors of the individuals under consideration. Such techniques were used by Lemey and colleagues to geographically trace the ancestors of 192 Avian influenza A-H5N1 strains sampled from twenty localities in Europe and Asia, and for 101 rabies virus sequences sampled across twelve African countries.