猩红热
Haemolytic streptococcus, which was identified in the 1880s, causes scarlet fever, which is a bacterial disease. Scarlet fever spreads through respiratory droplets and children between the ages of 5 to 15 years were most affected by scarlet fever. Scarlet fever had several epidemic phases, and around 1825 to 1885 outbreaks began to recur cyclically and often highly fatal. In the mid-19th century, the mortality caused by scarlet fever rose in England and Wales. The major outbreak in England and Wales took place during 1825–1885 with high mortality marking this as remarkable. There were several other notable outbreaks across Europe, South America, and the United States in the 19th century.