Structural analysis
There is extensive, predicted phosphorylation of C5orf34, with 32 phosphoserines and 7 phosphothreonines being conserved in orthologs of the human C5orf34 protein. This analysis indicates C5orf34 as a phosphoprotein and supports structural predictions of it being a kinase protein. The protein contains only one nuclear export signal residue, found at 481-L; however the NES score was found to be low at 0.515. Structural analysis of the protein indicated it was sequestered in the nucleus with an 87% probability.