Spanish Road
The irony of a Cardinal attacking the troops of a Pope was not lost on Rome, Spain, and ultra-Catholics in France. In 1625 the French marshals François de Bonne, Duke of Lesdiguières and Charles de Blanchefort, Marquis de Créquy, joined the Duke of Savoy, invaded the territories of the dominion of Genoa. An attack on Genoa would cut the southern end of the Spanish Road and knock out Spain's banker.