Amago clan
Motonari's eldest son, Mōri Takamoto, while "en route" to attack the Amago clan in 1563, died of a sudden disease, though assassination by poison was suspected. Saddened and angered by his death, Motonari ordered all those whom he thought responsible to be punished. Takamoto's son and Motonari's grandson Mōri Terumoto was selected as Motonari's heir, but Motonari continued to wield the true power of Mori clan.