Big Eyes
Hollywood actors Joan Crawford, Natalie Wood and Jerry Lewis commissioned Keane to paint their portraits. In the 1990s, Tim Burton, a Keane art collector and director of the 2014 biographical film "Big Eyes" about the life of Margaret Keane, commissioned the artist to paint a portrait of his then-girlfriend Lisa Marie. Keane's art was bought and presented to the United Nations Children's Fund in 1961 by the Prescolite Manufacturing Corporation. Keane's big eyes paintings have influenced toy designs, Little Miss No Name and Susie Sad Eyes dolls, and the cartoon "The Powerpuff Girls".