豊臣氏
In "Nioh", a game based on the events of the late Sengoku period, Ishida is featured as a strategist under the Toyotomi clan. After losing the Battle of Sekigahara, Mitsunari is betrayed by the antagonist Edward Kelley, an English alchemist, and transformed into a yokai (demon) by him. The protagonist William Adams must then fight the transformed Misunari in a boss battle.