Nativity play
In the clinic, House treats another female patient, Melanie, whom he initially diagnoses with strep throat. At the same time, he notices that she has had HIV tests every 3 months, and concludes that she is a prostitute. She later returns with pustules on her neck and chest. House asks if she does donkey shows, and when she says yes, he gives her a prescription for contagious ecthyma, a disease she has that can be caught from donkeys. At the end of the episode, House visits a church, which is putting on a Nativity play during which his clinic patient rides in on a donkey, playing the part of the Virgin Mary.