Diego Milito
On 29 June 2009, Acquafresca became a member of Genoa C.F.C. as a part of the deal that saw Diego Milito and Thiago Motta move to Internazionale, and moved along with Leonardo Bonucci, Francesco Bolzoni, Riccardo Meggiorini and Ivan Fatic. He was valued at €9.5 million at that time, signing a 5-year contract. He was immediately loaned to Atalanta as the club had recently sold its striker Sergio Floccari to Genoa.