مقاطعة ليتشي
Semeraro was born in Monteroni di Lecce, Province of Lecce, Italy. He was ordained to the priesthood on 8 September 1971. He received his Doctor of Theology degree in 1980 from the Pontifical Lateran University. On 25 July 1998 he was named Bishop of Oria. He was consecrated on 29 September 1998 by Archbishop Cosmo Francesco Ruppi with Archbishops Domenico Caliandro and Donato Negro as co-consecrators.