南部氏
The Nanbu clan sided with Tokugawa Ieyasu's Eastern Army during the Battle of Sekigahara. In the wake of Ieyasu's victory, the Nanbu clan was confirmed in its lordship of (also known as the ). The "kokudaka" of the domain was officially 100,000 "koku", but later in the Edo era, was doubled in amount. The Nanbu clan retained its holdings for the entirety of the Edo period, surviving until the Meiji Restoration. During the Edo period, two new branches of the Nanbu clan were founded, one at Hachinohe, and the other one at Shichinohe. In 1821, the old tensions between the Nanbu and Tsugaru flared once more, in the wake of the , a foiled plot by Sōma Daisaku, a former retainer of the Nanbu clan, to assassinate the Tsugaru lord. The Nanbu clan's territories were also among those effected by the Tenpō famine of the mid-1830s.