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Cheirisophus () was a Spartan general who fought with the Ten Thousand under Cyrus the Younger. Cheirisophus was sent by the Spartan ephors with 700 heavily armed men (800 according to Diodorus Siculus) to aid Cyrus the Younger in his expedition against his brother Artaxerxes in 401 BC. He joined Cyrus on his march at Issus in Cilicia. After the Battle of Cunaxa, Clearchus sent Cheirisophus with a delegation to the Persian general Ariaeus to make an offer of placing him on the Persian throne, an offer which Ariaeus declined.