Aloe vera
Aloin, a compound found in the semi-liquid latex of some "Aloe" species, was the common ingredient in over-the-counter (OTC) laxative products in the United States until 2002 when the Food and Drug Administration banned it because manufacturers failed to provide the necessary safety data. "Aloe vera" has potential toxicity, with side effects occurring at some dose levels both when ingested and when applied topically. Although toxicity may be less when aloin is removed by processing, "Aloe vera" ingested in high amounts may induce side effects, such as abdominal pain, diarrhea or hepatitis. Chronic ingestion of aloe (dose of 1 gram per day) may cause adverse effects, including hematuria, weight loss, and cardiac or kidney disorders.