USA Pro Cycling Challenge
A pair of top five time trial results in the 2006 Vuelta de Bisbie propelled him to a sixth place overall finish. Powers rode to prominence on the final stage of the 2008 Tour of Missouri, making half of the day's breakaway that was narrowly captured at the end of the stage. In September 2010, Powers won his first career stage race, winning Vermont's Green Mountain Stage Race by over two minutes ahead of 's Tim Johnson, Powers' Cannondale prepared by Cyclocrossworld.com teammate, and 's Gavin Mannion. Powers had a very successful 2011 road season with the team, participating in both of the United States' major tours – the Amgen Tour of California and the USA Pro Cycling Challenge. At the USA Pro Cycling Challenge, Powers got into the day's main break in stage 2, eventually won by George Hincapie.