بيت الحكمة
The Sassanid dynasty fell to Muslim Arab armies in 638 CE. The academy survived the change of rulers and persisted for several centuries, by projecting itself as a Muslim institute of higher learning. In 832 CE, Caliph al-Ma'mūn founded the "Bayt al-Hikma", the House of Wisdom. There the methods of Gundeshapur were emulated since the House of Wisdom was staffed with graduates of the older Academy of Gundeshapur who had been trained heavily in Indian and some Greek and Iranian medical traditions. It is believed that the House of Wisdom was disbanded under Al-Mutawakkil, Al-Ma'mūn's successor who felt learning conflicted with the information given in the Quran. In addition, the intellectual center of the Abbasid Caliphate had shifted to the Arab stronghold of Baghdad, as henceforth there are few references in contemporary literature to universities or hospitals at Gundeshapur.