Sazan Island
Despite her age and mechanical problems, she participated in the 1940-41 Greco-Italian War under the command of Lieutenant Commander Miltiadis Iatridis, carrying out six war patrols in the Adriatic. During one of these, on 22 December 1940, she sank the small Italian motor ship "Antonietta", and, on the very next day, the 3,952-ton troop carrier near Sazan Island. After the German invasion of April 1941, together with the rest of the fleet, "Papanikolis" fled to the Middle East, from where she would operate during the next years, carrying out nine war patrols in total.