Torneo de Bucarest
Delbonis next chose to compete at the 2016 Grand Prix Hassan II as the 4th seed. He received a bye pass for the first round. In the second round he defeated Thiemo de Bakker in straight sets. He then defeated 7th seed Pablo Carreño Busta in the quarterfinals also in straight sets. In the semifinals In the semifinals he defeated Albert Montañés once again in straight sets. He won his second career title without dropping a set the entire tournament by defeating 3rd seed Borna Ćorić in the final in straight sets. He then competed at the 2016 Monte-Carlo Rolex Masters. He had a disappointing loss to wildcard Fernando Verdasco 0–6, 3–6. Delbonis then played at the 2016 BRD Năstase Țiriac Trophy as the 3rd seed. He received a bye pass in the first round. In the second round he defeated Illya Marchenko in straight sets. In the quarterfinals he defeated Marco Cecchinato also in straight sets. In the semifinals he lost to Lucas Pouille 3–6, 2–6.