God's Wife of Amun
She was the first to hold the revived titles of God's Wife of Amun and Divine Adoratrice of Amun, both of which had been of great importance during the early 18th Dynasty but fell into disuse later. From her time on, the position of God's Wife became more and more influential, reaching the peak of its power during the Third Intermediate Period. Iset was probably the first God's Wife of Amun to live in celibacy (the previous holders of the title were queens, usually Great Royal Wives).