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The struggle between the northern Europeans and the Spanish spread southward in the mid to late seventeenth century, as English, Dutch, French and Spanish colonists, and in many cases their slaves from Africa first entered and then occupied the coast of The Guianas (which fell to the French, English and Dutch) and the Orinoco valley, which fell to the Spanish. The Dutch, allied with the Caribs of the Orinoco, would eventually carry the struggles deep into South America, first along the Orinoco and then along the northern reaches of the Amazon.