シリア戦争
Somewhere between 245 BC to 239 BC, her mother and Seleucus II arranged for her to marry King Mithridates II of Pontus. Laodice married Mithridates II, as a part of a political alliance between the Seleucid Empire and the Kingdom of Pontus. In 245 BC, her mother and Seleucus II were in the Third Syrian War Third Syrian War. To gain support from the Kingdom of Pontus, Laodice was given to Mithridates II in marriage and as a marriage gift, Phrygia was transferred as well.