Museo di Capodimonte
Polidoro's main paintings include a "Crucifixion", painted in Messina, and a "Deposition of Christ" (1527) and a "Christ Carrying the Cross" (1530–34) both in the Museo di Capodimonte of Naples, who have the best collection of his work (an oil sketch for the latter is in the National Gallery, London). They are very individual in style, extremely free in technique, and powerful in expression. The "Christ bearing the Cross" shows considerable Northern influence, probably reflecting the traditionally strong links between Sicily and the Netherlands.