Episcopal see
Francis I entrusted him with several important missions; in 1529 he accompanied Louise de Savoie to Cambrai and concluded peace with Charles V. In 1533 at Marseilles he arranged with Clement VII for the marriage of the Duc d'Orléans (Henri II) and Catherine de' Medici. He obtained permission for the translation of his Episcopal see from Maguelonne to Montpellier from Paul III in 1536.