注意欠陥・多動性障害
Attention deficit hyperactivity disorder (ADHD) has been associated with sensorimotor deficits and the central sulcus divides both somatosensory and primary motor areas prompting  research into how the shape of the central sulcus and ADHD may alter brain development in these individuals. The cortical thickness and average and maximum depth of the central sulcus has been shown to be larger for ADHD individuals when compared to neurotypical individuals. Additionally, changes in the middle sections of the central sulcus have been linked to children with ADHD.