克里斯蒂安二世
On May 4, 1534 he married the 12-year-old niece of Charles V, Christina of Denmark, the daughter of Christian II of Denmark and Isabella of Burgundy. The union remained childless. His death in 1535 sparked the Italian War of 1535. His half-brother Giovanni Paolo reclaimed briefly the Duchy of Milan after his death, but died in the same year under mysterious circumstances.