Толедский собор
As a young man, before he took Holy Orders, he had an illegitimate son, Bartolomé de la Cueva. Following his ordination, he was a cleric in the Diocese of Segovia, and a canon of the cathedral chapter of Toledo Cathedral. He also worked for the Apostolic See in Spain. In 1525, he and his brother Luis accompanied Charles V, Holy Roman Emperor during the emperor's visit to Italy.