Río Biobío
In 1642, the Dutch East India Company joined the Dutch West Indies Company in organizing an expedition to Chile to establish a base for their trade at the west coast of South America. Valdivia, Chiloé Island and Santa María Island came into consideration because they were isolated from Chile but with harbours. Valdivia, like all cities south of Bío Bío River, had been abandoned by Spaniards and destroyed by the Mapuches in 1599 during the Destruction of the Seven Cities.