Schlacht bei Issos
Earlier depictions of the Battle of Issus are few. "Battle of Issus", a fresco by Philoxenus of Eretria, is probably the first such. It was painted sometime around 310 BC for Cassander (c. 350–297 BC), who was one of Alexander the Great's successors. Alexander and Darius – each within a lance's length of the other – are pictured among a wild fray of mounted and downed soldiers. While Alexander maintains an aura of unshaken confidence, fear is etched in Darius' face, and his charioteer has already turned to rein his horses and escape. Roman author and natural philosopher Pliny the Elder claimed that Philoxenus' portrayal of the battle was "inferior to none". Some modern critics posit that "Battle of Issus" might not have been the work of Philoxenus, but of Helena of Egypt. One of the few named women painters who might have worked in Ancient Greece, she was reputed to have produced a painting of the battle of Issus which hung in the Temple of Peace during the time of Vespasian.