Cosimo III de' Medici, Grand Duke of Tuscany
Anna Maria Luisa was the only daughter of Cosimo III de' Medici, Grand Duke of Tuscany, and Marguerite Louise d'Orléans, a niece of Louis XIII of France. On her marriage to Elector Johann Wilhelm II, she became Electress of the Palatinate, and, by patronising musicians, she earned for the contemporary Palatine court the reputation of an important music centre. As Johann Wilhelm had syphilis the union produced no offspring, which, combined with her siblings' barrenness, meant that the Medici were on the verge of extinction.