Agrippina the Younger
The tropane alkaloids of "A. belladonna" were used as poisons, and early humans made poisonous arrows from the plant. In Ancient Rome, it was used as a poison by Agrippina the Younger, wife of Emperor Claudius on the advice of Locusta, a woman who specialized in poisons, and Livia, who is rumored to have used it to kill her husband Emperor Augustus.