Sōsuke Aizen
There, Orihime is introduced to Sōsuke Aizen, a former Soul Reaper and current leader of the Arrancar. Aizen explains that he intends to use Orihime's "Shun Shun Rikka" to restore the , though she decides to use her powers to destroy the Orb instead. Before she can act on her plans, Ichigo and a group of others arrive in Hueco Mundo to save her. When Ichigo is defeated while facing Ulquiorra, Grimmjow Jeagerjaques, wanting to battle Ichigo at full strength, frees Orihime from her confinements so that she can heal him. Ichigo battles with Grimmjow and ultimately claims victory. They are then attacked by Nnoitora Jiruga, but after Nnoitora's death at the hands of Kenpachi, Orihime is captured once again. Ichigo rushes to her location, and engages Ulquiorra in battle, but is once again defeated. During the aftermath, she discovers that Ichigo is transformed into a new hollow and he mortally hurts Ulquiorra. Ulquiorra starts to turn into ashes as he asks Orihime if she is afraid of him. Orihime, after saying that he is not frightening, tries to reach his hand but Ulquiorra finally disappears. As Ichigo returns to the world of the living, Orihime remains behind to heal an injured Uryū.