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As a soloist, Lateiner appeared with many of the world's leading conductors, including Leonard Bernstein, Serge Koussevitzky, Erich Leinsdorf, Zubin Mehta, Georg Solti and George Szell. He was a champion of contemporary American music, and commissioned, premiered and recorded Elliott Carter's piano concerto. The premiere took place at Symphony Hall, Boston, on January 6, 1967, with Lateiner as soloist accompanied by the Boston Symphony Orchestra, with Erich Leinsdorf conducting. He also premiered the third piano sonata of Roger Sessions.