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International expansion followed throughout the 1950s: a filter production factory was opened in South Africa, while a separately-run company named American Filtrona was set up in the United States in 1954. Use of cigarette filters increased markedly in the 1950s as links between smoking and cancer were established, and Bunzl soon became the exclusive supplier to both Imperial Tobacco and Gallaher Group. Between 1956 and 1964, Bunzl's production of filters increased by a factor of twelve.