Nikkō Line
The highway begins at a junction near Rinnō-ji with National Routes 120 and 122 and Tochigi Prefecture Route 247 in Nikkō. From there it travels southwest through the central district of the city, where it begins running parallel with the Tōbu Nikkō Line and the Nikkō Utsunomiya Road. Within the former city of Imaichi, the highway has junctions with National Routes 121, 352, and 461—sharing a brief concurrency with the former two of the three routes. Crossing into Utsunomiya, the highway begins gradually curving to the south still paralleling the Nikkō Utsunomiya Road, but moving away from the Tōbu Nikkō Line.