Lanceur partant
The new season brought a Cardinals team that was much changed from the one that went 100-62 in 2005 but fell to the Houston Astros in the NLCS. Starting pitcher Matt Morris, second baseman Mark Grudzielanek, left fielder Reggie Sanders, and relief pitcher Julián Tavárez left the team via free agency. Relief pitcher Ray King was traded to Colorado. Right fielder Larry Walker retired. Brought in to replace the departed Cardinals were right fielder Juan Encarnación, starting pitcher Sidney Ponson, relief pitchers Braden Looper and Ricardo Rincón, all via free agency, and second baseman Aaron Miles, acquired in the Ray King trade. Left field was left unsettled in the offseason and would remain so all year, with no player getting more than one-third of the playing time at that position.