Latin American Episcopal Conference
On 30 January 1950, Samorè was appointed Apostolic Nuncio to Colombia and Titular Archbishop of Ternobus by Pope Pius XII. He received his episcopal consecration on the following 16 April from Clemente Micara, with Archbishop Filippo Bernardini and Bishop Alberto Carinci serving as co-consecrators, in the church of Santa Maria sopra Minerva. Samorè later returned to Rome upon his naming as Secretary of the Congregation for Extraordinary Ecclesiastical Affairs on 7 February 1953. As Secretary, he was the second-highest official of that dicastery. Before and after the Second Vatican Council (1962–1965), later as President of the Pontifical Commission for Latin America, he was charged by Pope Paul VI to stem support of liberation theology and "ecclesial base communities" by the Latin American Episcopal Conference (CELAM).