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Christie portrayed the female lead in "Away from Her" (2006), a film about a long-married Canadian couple coping with the wife's Alzheimer's disease. Based on the Alice Munro short story "The Bear Came Over the Mountain", the movie was the first feature film directed by Christie's sometime co-star, Canadian actress Sarah Polley. She took the role, she says, only because Polley is her friend. Polley has said Christie liked the script but initially turned it down as she was ambivalent about acting. It took several months of persuasion by Polley before Christie finally accepted the role.