張献忠
At the fall of the Ming, the rebel Zhang Xianzhong established his Great Western Kingdom () with its capital at Chengdu; it lasted only from 1643 to 1646. Zhang was said to have massacred a large number of people in Chengdu and throughout Sichuan. In any case, Chengdu was said to have become a virtual ghost town frequented by tigers and the depopulation of Sichuan necessitated the resettlement of millions of people from other provinces during the Qing dynasty. Following the Columbian Exchange, the Chengdu Plain became one of China's principal sources of tobacco. Pi County was considered to have the highest quality in Sichuan, which was the center of the country's cigar and cigarette production, the rest of the country long continuing to consume snuff instead.