Derby della Madonnina
On 27 November, Milito earned his 400th career appearance in the league match at Siena, which ended with a 1–0 away win for "Nerazzurri", while on 18 December, in a 1–0 win over Cesena, he played his 100th game in Serie A. In December, due to his poor performances during the previous season, Milito was awarded the Bidone d'oro, a satirical prize which is given to the worst Serie A player during a particular season. On 21 December, he scored in a 4–1 win against Lecce in Inter's last match of 2011. On 7 January 2012, he scored twice and assisted goal of Giampaolo Pazzini in a 5–0 win against Parma at San Siro. On 15 January 2013, Inter won the Derby della Madonnina against Milan with the result 1–0, with Milito who scored the only goal in 54th minute after an assist from Javier Zanetti, his 200th for an Italian club across all competitive competitions. With his goal at Milan, he has scored seven goals in just nine derby matches played in Italy – four goals in four games in the Derby della Lanterna for Genoa against Sampdoria and three in five in the Derby della Madonnina.