Hōjō Ujiyasu
Kenshin heading a campaign against the Hōjō Ujiyasu from fall 1560 to the summer of 1561, Kenshin was successful in taking a number of castles from the clan, like Numata and Umayabashi castles, which ended with the first siege of the Odawara Castle in Sagami Province. He managed to break the defenses and burn the town, but the castle itself remained unconquered due to threats from Shingen, and thus seized Kamakura. In 1561, Kenshin saved his ally Ōta Sukemasa who was under siege by both Ujiyasu and Shingen, while in November 1569 when Shingen sieged Odawara Castle, Ujiyasu requested help from Kenshin.