Muhammad Shaybani
Muhammad Shaybani, the Khan of the Uzbeks, had set up the Khanate of Bukhara and was so powerful and successful in his military exploits that he wrested Samarkand, Herat, and Bukhara from the Timurid dynasty. He captured Khurasan as well but by 1510 he found in Shah Ismail I, the founder of a new Safavid Persian Empire, a serious threat. He decided to confront this threat head on and marched towards Merv where his army was ambushed by the Persians. Some 17,000 Qizilbash ambushed and defeated a superior Uzbek force numbering 28,000. The Uzbek ruler, Muhammad Shaybani, was caught and killed.