Temporal lobe
Disconnection syndromes, defined as any neurologic disorder caused by an interruption in impulse transmission along cerebral fiber pathways, can cause white matter brain lesions, leading to secondary neuronal loss and transneuronal degeneration. Secondary neuronal loss occurs as a result in areas that are strongly connected with the severed tracts or restricted cortex during an anterior temporal lobectomy. Temporal lobe lesions also cause transneuronal degeneration, the effects of which can be seen in the fornix, mammillary bodies, and contralateral cerebellum.