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The old name of the town was Ecsed but over time it has been renamed Nagyecsed, meaning "grand" or "great Ecsed" to distinguish it. The area had close associations with a cadet branch of the Báthory family. Elizabeth Báthory was raised in the town's now ruined castle. Her main residence and later her prison was Csejte Castle, Upper Hungary, now in Slovakia, but she was buried in the family crypt at Ecsed.