サン・ジョヴァンニ洗礼堂
Giotto in his 1305 painting in the Scrovegni Chapel (Padua) shows an allegory of charity (caritas) handing her heart to Jesus Christ. This heart is also depicted in the pine cone shape based on anatomical descriptions of the day (still held "upside down"). Giotto's painting exerted considerable influence on later painters, and the motive of Caritas offering a heart is shown by Taddeo Gaddi in Santa Croce, by Andrea Pisano on the bronze door of the south porch of the Florence Baptistery (), by Ambrogio Lorenzetti in the Palazzo Publico in Siena () and by Andrea da Firenze in Santa Maria Novella in Florence (). The convention of showing the heart point upward switches in the late 14th century and becomes rare in the first half of the 15th century.