內政大臣
On 12 May 2010, when May was appointed Home Secretary and Minister for Women and Equalities by Prime Minister David Cameron as part of his first Cabinet, she became the fourth woman to hold one of the British Great Offices of State, after Margaret Thatcher (Prime Minister), Margaret Beckett (Foreign Secretary) and Jacqui Smith (Home Secretary). As Home Secretary, May was also a member of the National Security Council. She was the longest-serving Home Secretary for over 60 years, since James Chuter Ede who served over six years and two months from August 1945 to October 1951. May's appointment as Home Secretary was somewhat unexpected, with Chris Grayling having served as shadow Home Secretary in opposition.