Upland South
In addition, the Cotton Belt of the Deep South was controlled by Indians (mainly the Five Civilized Tribes of the Cherokee, Creek (Muscogee), Chickasaw, Choctaw, and Seminole) who were powerful enough to keep pioneering settlers from moving into the region. The Deep South's cotton boom did not occur until after the Indians were forced west in the early 19th century. In contrast, the Upland South, Kentucky, and Tennessee especially, were the scene of Indian resistance and pioneering settlement during the late 18th century. Thus the Upland South colonized earlier and had established its particular settlement patterns before most of the Deep South was opened to general colonization.