Frederick VII of Denmark
Christian first married his cousin Duchess Charlotte Frederica of Mecklenburg-Schwerin at Ludwigslust on 21 June 1806. Charlotte Frederica was a daughter of Friedrich Franz I, Grand Duke of Mecklenburg-Schwerin, and Princess Louise of Saxe-Gotha-Altenburg (1756-1808). His first-born son was Christian Frederik, who was born and died at Schloss Plön on 8 April 1807. His second son became Frederick VII of Denmark. The marriage was dissolved by divorce in 1810 after Charlotte Frederica was accused of adultery.