Lead poisoning
Over her career, Clayton published more than 200 academic papers. Concerned with the high levels of lead found in children's blood she co-authored, with five others, the article ‘Lead poisoning in children’ ("Arch dis child" 1964, 39, 1-13) and while a member of the Royal Commission on Environmental Pollution in the 1980s, campaigned and lobbied the UK government to enforce a ban on lead in petrol, paint and other products.