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The oratory is best known for its late Gothic style fresco cycle (1416) by the brothers Lorenzo and Jacopo Salimbeni. The subjects include a Madonna dell’Umiltà and a Crucifixion, In addition the oratory has scenes from the life of John the Baptist such as: the "Annunciation of Birth"; his "Baptism of Jesus", "Career in Baptizing", and "Sermons of St John".