Francesco I Sforza
In the beginning, Assisi fell under the rule of Perugia and later under several despots, such as the soldier of fortune Biordo Michelotti, Gian Galeazzo Visconti and his successor Francesco I Sforza, dukes of Milan, Jacopo Piccinino and Federico II da Montefeltro, lord of Urbino. The city went into a deep decline through the plague of the Black Death in 1348.