Osvaldo Ardiles
Famous players who have played at Instituto include Osvaldo Ardiles, Mario Alberto Kempes, José Luis Saldaño, Hugo Curioni, Alberto Beltrán, Raúl de La Cruz Chaparro, Salvador Mastrosimone, Marcelo Bielsa, Ernesto Corti, Diego Klimowicz, Mauricio Caranta, Oscar Dertycia, Alejandro Faurlín, Gonzalo Bergessio, Daniel "Miliki" Jiménez, Paulo Dybala, Ramón Ábila, Silvio Romero.