Epipactis helleborine
In terms of biosynthesis, oxycodone has been found naturally in nectar extracts from the orchid family "Epipactis helleborine"; together along with another opioid: 3-{2-{3-{3-benzyloxypropyl}-3-indol, 7,8-didehydro- 4,5-epoxy-3,6-d-morphinan.