Nyuserre Ini
Owing to the paucity of contemporaneous sources for Menkauhor, his relation to his predecessor, Nyuserre Ini, and to his successor, Djedkare Isesi, cannot be ascertained beyond doubt. Menkauhor may have been a son of Nyuserre Ini; indeed Nyuserre Ini is known to have fathered a prince Khentykauhor as shown by a relief mentioning the prince from the mortuary complex of queen Khentkaus II, the mother of Nyuserre Ini. The similarity of Khentykauhor's name to that of Menkauhor led the Egyptologists Miroslav Verner and Vivienne Callender to propose that the two are the same person, with Khentykauhor taking the name "Menkauhor" upon ascending the throne. This hypothesis is possibly contradicted by an inscription discovered in 2008 in the mastaba of Werkaure, the eldest son of an unnamed king. The inscription mentions a "Menkauhor", but does not ascribe any royal attributes to him. The Egyptologists Hana Vymazalová and Filip Coppens suggest this might refer to the future pharaoh Menkauhor Kaiu at a time when he was still a prince. They note that Menkauhor might have offered high-quality stone blocks for the construction of the tomb of his (possible) relative, which would explain the inscription. This contradicts the identification of Menkauhor with Khentykauhor; Vymazalová and Coppens theorize that Khentykauhor and Menkauhor were brothers and sons of Nyuserre Ini.