ウニ
During early development, the sea urchin embryo undergoes 10 cycles of cell division, resulting in a single epithelial layer enveloping the blastocoel. The embryo then begins gastrulation, a multipart process which dramatically rearranges its structure by invagination to produce the three germ layers, involving an epithelial-mesenchymal transition; primary mesenchyme cells move into the blastocoel and become mesoderm. It has been suggested that epithelial polarity together with planar cell polarity might be sufficient to drive gastrulation in Sea urchin.