تلف الدماغ
The primary auditory cortex is located on the temporal lobe of the cerebral cortex. This region is important in music processing and plays an important role in determining the pitch and volume of a sound. Brain damage to this region often results in a loss of the ability to hear any sounds at all. The frontal cortex has been found to be involved in processing melodies and harmonies of music. For example, when a patient is asked to tap out a beat or try to reproduce a tone, this region is very active on fMRI and PET scans. The cerebellum is the "mini" brain at the rear of the skull. Similar to the frontal cortex, brain imaging studies suggest that the cerebellum is involved in processing melodies and determining tempos. The medial prefrontal cortex along with the primary auditory cortex has also been implicated in tonality, or determining pitch and volume.