Tranexamic acid
Tranexamic acid decreases death in people who are having ongoing bleeding due to trauma, as well as those with mild to moderate traumatic brain injury and evidence of intracranial bleeding on CT scan. It only appears to be beneficial, however, if administered within the first three hours after trauma. For severe bleeding, for example from bleeding disorders, recombinant factor VIIaa protein that assists blood clottingmay be appropriate. While it decreases blood use, it does not appear to decrease the mortality rate. In those without previous factor VII deficiency, its use is not recommended outside of trial situations.