خليفة بن زايد آل نهيان
Sheikh Issa is the son of Zayed bin Sultan. His mother is Sheikha Amna bint Salah Al Badi. He has one full-brother, late Sheikh Nasser. The present UAE ruler, Sheikh Khalifa bin Zayed Al Nahyan, and the Crown Prince, Mohammed bin Zayed Al Nahyan, are the half brothers of Sheikh Issa.