Clostridium perfringens
Oritavancin is active against gram-positive aerobic bacteria such as enterococci, staphylococci, streptococci, and anaerobic bacteria such as "Clostridium difficile" , "Clostridium perfringens" , "Peptostreptococcus spp." , and "Propionibacterium acnes." Oritavancin’s spectrum of activity shows similarities to vancomycin, but with lower minimum inhibitory concentrations (MIC).