Motagua River
The Sierra de Chuacús is situated in the central highlands of Guatemala, and runs southeast from El Quiché to Baja Verapaz. Its northwestern border is marked by the Chixoy River basin in Uspantán, which separates it from the Sierra de los Cuchumatanes. Its eastern border is marked by the Salamá River which separates it from the Sierra de las Minas. Its southeastern border is defined by the Motagua River valley.