Fuzzy logic
Fuzzy logic is a system of reasoning that enables an artificial neural network to deal in non-binary and linguistic variables. Biological data is often unable to be processed using Boolean logic, and moreover accurate modeling of the capabilities of biological nervous systems requires fuzzy logic. Therefore, artificial neural networks that incorporate it, such as evolving fuzzy neural networks (EFuNN) or Dynamic Evolving Neural-Fuzzy Inference Systems (DENFIS), are often used in computational neurogenetic modeling. The use of fuzzy logic is especially relevant in gene regulatory networks, as the modeling of protein binding strength often requires non-binary variables.