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Ithaca is a 2015 American drama film directed by Meg Ryan and written by Erik Jendresen. It is based on the 1943 novel "The Human Comedy" by William Saroyan. The film stars Alex Neustaedter, Jack Quaid, Meg Ryan, Sam Shepard, Hamish Linklater and Tom Hanks. The film was released on September 9, 2016, by Momentum Pictures.