개막전
The Padres' first Opening Day starting pitcher was Dick Selma, who received a win against the Houston Astros. Randy Jones, Eric Show and Jake Peavy tie the Padres' record for most Opening Day starts with four. Peavy has the most consecutive Opening Day starts with four (2006–2009). Jones and Andy Benes each have had three consecutive Opening Day starts. Benes has the most consecutive Opening Day losses with three from to .