Battle of Marj Dabiq
The Ottoman Empire conquered Syria from the Mamluks following the Battle of Marj Dabiq in August 1516 and the subsequent pledges of allegiance paid to the Ottoman sultan, Selim I, in Damascus by delegations of notables from throughout Syria. The Ottomans established Damascus as the center of an "eyalet" (Ottoman province) whose territories consisted of the "mamlakat" (Mamluk provinces) of Damascus, Hama, Tripoli, Safad and Karak. The "mamlaka" of Aleppo, which covered much of northern Syria, became the Aleppo Eyalet. For a few months in 1521, Tripoli and its district were separated from Damascus Eyalet, but after 1579, the Tripoli Eyalet permanently became its own province.