John III Doukas Vatatzes
Marie was Empress of Nicaea from 1219 to November, 1221 when Theodore died. They had no known children. One of her stepdaughters, Maria Laskarina, became the wife of King Béla IV of Hungary, and the other, Irene Lascarina, was married to John III Doukas Vatatzes who took over the throne of the Nicaean Empire. Marie briefly served as regent of Nicaea in 1222.