京都所司代
Tadaaki was reappointed as the 52nd "Kyoto Shoshidai" from August 5, 1858, through July 26, 1862. Many of the events which occurred in Kyoto during the tumultuous Bakumatsu period occurred while he was at Kyoto. During this period, he served as chief intermediary between the shogunate in Edo and Emperor Kōmei during a period of extensive negotiations, delays, and political maneuvering which accompanied plans for the eventual marriage of Komei's sister, Princess Kazunomiya, and Tokugawa Iemochi in March 1862.