破傷風菌
Synaptobrevin is degraded by tetanospasmin, a protein derived from the bacterium "Clostridium tetani", which causes tetanus. A related bacterium, "Clostridium botulinum", produces the botulinum toxin. Various botulinum toxin serotypes exist that each cleave specific peptide bonds of specific neuronal SNARE proteins, and synaptobrevin is this target protein for several of the serotypes.