Amédée VIII de Savoie
Margaret was born in April 1439 in Turin, Italy, the eldest surviving daughter and one of the nineteen children of Louis I, Duke of Savoy and Princess Anne of Cyprus. Her paternal grandparents were Amadeus VIII of Savoy, who was also the Antipope Felix V, and Mary of Burgundy. Her maternal grandparents were King Janus of Cyprus and Armenia and Charlotte de Bourbon.