序列分析
A systematic survey of 2,2,7-trimethylguanosine (TMG) 5′ capped transcripts in "C.elegans" using anti TMG antibodies identified two TMG capped SmY transcripts. Sequence analysis of the potential Sm binding sites in these transcripts indicated the SmY, U5 snRNA, U3 snoRNA and the spliced leader RNAs transcripts (SL1 and SL2) all contain a very similar consensus SM binding sequence (AAU4–5GGA). The predicted SM binding sites identified in the U1, U2 and U4 snRNA transcripts varied from this consensus.