Battle of Ipsus
After Alexander's death in 323 BC, his generals, the Diadochi, divided up the territory he had conquered. After the Battle of Ipsus in 301 BC, Seleucus I Nicator won the territory of Syria, and he proceeded to found four "sister cities" in northwestern Syria, one of which was Antioch, a city named in honor of his father Antiochus; according to the "Suda", it might be named after his son Antiochus. He is reputed to have built sixteen Antiochs.