Palms Casino Resort
On February 17, 2015 Showtime announced that Martirosyan would appear on a doubleheader at the Palms Casino Resort in Las Vegas on March 28 against Jermell Charlo (25-0). The fight was contested over 10 rounds. Martirosyan lost a contentious unanimous decision. He was considered the more aggressive fighter. The scores were 97–93, 96–94, 96–94. Martirosyan felt he won the fight.