カーロス・コンディット
Lytle was expected to face Carlos Condit on February 27, 2011, at UFC 127. However, Condit was forced from the bout after suffering a knee injury while training and replaced by UFC newcomer Brian Ebersole. Lytle was defeated by Ebersole via unanimous decision (30–27, 29–28, and 29–28), again winning "Fight of the Night".