Sakai clan
Isesaki Domain was originally created in 1601 for Inagaki Nagashige, a hatamoto formerly in the service of the Imagawa clan who had transferred his allegiance to Tokugawa Ieyasu. After Tokugawa Ieyasu took control over the Kantō region in 1590, he assigned estates with revenues of 3000 "koku" to Inagaki Nagashige in Kōzuke Province, and entrusted him with the defense of Ogo Castle. He was awarded additional estates in 1601, following Ieyasu’s defeat at the hands of Uesugi Kagekatsu at Aizu, which elevated him to the rank of "daimyō". His son was transferred in 1616, and Isesaki was thereafter ruled by three junior branches of the Sakai clan until the end of the Edo period.