火枪手
The annual Crosstown Shootout was held on January 6, 2011, pitting the Musketeers against archrival Cincinnati. In what was Xavier's lowest-scoring game in seven years, the Musketeers lost in convincing fashion 66–46. The Bearcats, meanwhile, improved to 15–0, equalling their second best start. Xavier hit one shot from beyond the arc on ten attempts. The Musketeers were led by Jamel McLean's 18 points, while Tu Holloway was held to five, well below his season average.