Hua Tuo
Hua Tuo's biography in the "Houhanshu" explains this "mafeisan" "numbing boiling powder" decoction was dissolved in "jiu" (; literally "alcoholic beverage; wine"). His prescription for "mafeisan" anaesthetic liquor was lost or destroyed, along with all of his writings. The "Book of Sui" lists five medical books attributed to Hua Tuo and his disciples, but none are extant.