Wei Zhongxian
When her charge succeeded to the throne as the Tianqi Emperor at the age of fifteen in 1620, he gave Madame Ke the title of "Lady Fengsheng" ("Fengsheng furen"), gave her son and brother imperial privileges as battalion commanders of the Imperial Bodyguard, and appointed Wei Zhongxian to the prestigious office of eunuch custodian of the Imperial brushes at the Directorate of the Ceremonial. Together, Madame Ke and Wei Zhongxian purged the imperial court of their enemies and took control over state affairs in a de facto rule referred to as "Ke-Wei".