Medical device
The overall economic impact of the bioscience industry in Ohio, including healthcare, amounted to $148.2 billion in 2007, representing 15.7% of Ohio's economic output. Half of the biotech industry is located in northeast Ohio, with 574 firms, while central and southern Ohio are home to around 200 each. 635 companies are FDA-certified to manufacture medical devices. Biotech research and development employs directly 12,415 residents, while agricultural bioscience contributed the largest economic impact, at $10.7 billion. Medical device manufacturers employ 9,757 residents.