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He served alongside of John Baillie and Henry P. Van Dusen as a general editor of the Library of Christian Classics series, which includes modern translations of the writings of Christian theologians and thinkers such as Aquinas, Augustine, Calvin, Luther and other reformers and early church fathers. McNeill himself was the chief editor of the series' release of John Calvin's Institutes of the Christian Religion in two volumes. The production of this most recent English translation (released in 1960) of the French Reformer's "magnum opus" was the work of several Latin scholars and theologians on both sides of the Atlantac.