Multiple sclerosis
Multiple sclerosis is a disease that demyelinates the nerves of the central nervous system, leading to deteriorated bodily function. The underlying pathologies are mostly unknown and not understood. It is hypothesized by many that the demyelination in multiple sclerosis lesions leads to axonal transection and ultimately axonal degeneration. This axon death could potentially be the cause of the irreversible effects of multiple sclerosis. Using what is known about the axotomy response, doctors and researchers are looking to implement neuro-protective rehabilitation to patients suffering in the early stages of multiple sclerosis in order to prevent the disease from running its course and causing irreversible disability. These rehabilitations would include the utilization of trophic factors to aid in neuron survival and maintenance of synapsing function.