Frankenbahn
Line 45 starts in Cologne main station and stops between Frankfurt and Cologne at some stations of the Cologne–Frankfurt high-speed rail line. At the end of the high-speed line, it runsto the west and goes via Wiesbaden and Mainz to Stuttgart. In the period of the federal horticulture show (being held in Heilbronn) in 2019, one train pair (ICE 714/715) runs on weekdays via the Franconia Railway and the southern Franconia Railway with additional stops in Heilbronn (no stop in Vaihingen (Enz)).