破傷風菌
Nightingale's theory was shown to be applicable during the Crimean War when she, along with other nurses she had trained, took care of injured soldiers by attending to their immediate needs, when communicable diseases and rapid spread of infections were rampant in this early period in the development of disease-capable medicines. The practice of environment configuration according to patient's health or disease condition is still applied today, in such cases as patients infected with "Clostridium tetani" (suffering from tetanus), who need minimal noise to calm them and a quiet environment to prevent seizure-causing stimulus.