Lake Suwa
"Blood-C" is set in an isolated rural town on the shore of Lake Suwa in Nagano Prefecture. Saya Kisaragi is the shrine maiden of the Shinto shrine run by her father Tadayoshi, and is outwardly a friendly and clumsy high school girl—her circle of friends include neighbor and cafe owner Fumito Nanahara; school friends Yūka Amino, twins Nene and Nono Motoe, class president Itsuki Tomofusa, the taciturn Shinichirō Tokizane; and Saya's schoolroom teacher Kanako Tsutsutori.