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Considered one of the ideologists and activists of the "Prometheist" policies that sought to destabilize the Soviet Union by encouraging national uprisings among the non-Russian nations that had been conquered by the Soviet Union, particularly the Ukrainians and the peoples of the Caucasus, Hołówko took an active part in preparing the 1929 Soviet-Polish treaty, called the Litvinov's Pact after the Soviet diplomat Maxim Litvinov. In his published comments to the Treaty, Hołówko stated apparently contrary to the "Prometheian" ideas that the Soviet control over Dnieper Ukraine is the most beneficial condition for the Polish "solution of the Ukrainian problem" as any genuinely Ukrainian government would have likely raised territorial claims towards Polish state. On the other hand, he was frequently cited as an advocate for independence of Ukraine, Belarus and other countries.