قسطنطين الحادي عشر
Zoe was born in the Morea in 1449, to Thomas Palaiologos, Despot of the Morea and younger brother of the last Byzantine Emperor, Constantine XI Palaiologos (). Her mother was Catherine, the only legitimate daughter and heiress of Centurione II Zaccaria, the last independent Prince of Achaea and Baron of Arcadia.