Back pain
All PDE5 inhibitors are generally well tolerated. The occurrence of side effects, or adverse drug reactions (ADRs), with PDE5 inhibitors depends on the dose and type of agent. Headache is a very common ADR, occurring in &gt;10% of patients. Other common ADRs include: dizziness, flushing, dyspepsia, nasal congestion or rhinitis. Back pain and muscle aches are also more common in patients taking tadalafil.