중증급성호흡기증후군
Sarsgaard hosted "Saturday Night Live" ("SNL") on January 21, 2006. In his introductory monologue, he tried to point out that he was a nice guy despite his sometimes macabre roles. Video clips were then played of Sarsgaard scaring the "SNL" cast. One sketch featured the Severe acute respiratory syndrome (SARS) global scare, which was still fresh in many minds, and one of the skits included a promotion for the Peter Sarsgaard "SARS-Guard", a reference to the mania of facemasks worn in public by those fearing infection.