Certosa di Pavia
He later worked in Milan and its environs. During the 1650s, Nuvolone painted frescoes for the Cappella di San Michele in the Certosa di Pavia and contributed to the decorations of the sacro monte (hillside shrine) at Varese, an important local pilgrimage site. He later also painted frescos at the Sacro Monte di Orta. His brother occasionally assisted him with his fresco work.