DNA methylation
Studies have also looked at methyl deoxycytidine residues from tissues collected from rodents at various ages. These studies found that DNA methylation loss increased significantly as the rodent aged. Thus, aging is related to a significant loss in DNA methylation. However, this loss of DNA methylation appears to be slowed by physical exercise under rare conditions, in generel this effect is not very well studied and so far it seems like there is no connection between DNA methylation and physical activity. Further studies have looked at the effects of physical exercise on DNA methylation and aging in humans.