County highway
SR 95 begins at an intersection with SR 52 in Columbia and proceeds north as Main Street. South of Columbia, the route is designated as County Road 95 that goes south through Gordon and then reaching the Florida state line and continuing as County Road 164, which leads to County Road 271 and Sneads. It intersects SR 134's eastern terminus as it exits town. It runs parallel with the Chattahoochee River (Alabama-Georgia State Line) as it proceeds north. It then passes through Haleburg and then enters Abbeville. The stretch from County highway 30 north of Columbia to Abbeville is designated as the George H. Grimsley Highway. In Abbeville, SR 95 intersects SR 10, running near SR 27. It then crosses over Vann Mill Creek and then Little Abbie Creek, running by Mathison Lake. Then, the route passes through White Oak and crosses over the White Oak Creek before reaching its northern terminus at US 431/SR 1 south of Eufaula.