Arthur, Prince of Wales
Isabella did, however, make successful dynastic matches for her two youngest daughters. The death of Isabella of Aragon created a necessity for Manuel I of Portugal to remarry, and Isabella's third daughter, Maria of Aragon, became his next bride. Isabella's youngest daughter, Catherine of Aragon, married England's Arthur, Prince of Wales, but his early death resulted in her being married to his younger brother, King Henry VIII of England.