井伊直弼
The death of Tairō Ii Naosuke started a wave of loyalist terrorism across Japan, the poet Tsunada Tadayuki even wrote a poem praising Ii's assassins. Soon attempts were being made on the lives of other members of the bakufu and their informants. The wave of popular dissent also turned against officials with a connection to Ii Naosuke, no matter how distant it was. Shimada Sakon, retainer of the Kujō, (one of the Sekke families; the 5 regent houses, and among the most powerful in the court), Imperial regent, was killed by dissidents for supporting the Harris treaty and helping Ii’s confidant, Nagano Shuzen, expose members of the court who were targeted during the Ansei purge.