助理主教
The bishopric's fate was sealed with the Protestant Reformation, which was enforced here during the episcopate of Prince Adolph II of Anhalt, who was driven out of office by his uprising subjects during the German Peasants' War in 1525. In 1544 Elector Augustus of Saxony finally assumed the rule as Protestant administrator, with Prince George III of Anhalt as Coadjutor bishop. In 1561 the Saxon elector installed his minor son Alexander as administrator, who nevertheless died four years later, whereafter the Bishopric of Merseburg was finally incorporated by the Saxon electorate. From 1652 to 1738 the descendants of the Wettin duke Christian I held the title of a "Duke of Saxe-Merseburg".