Francis I, Holy Roman Emperor
Although she had only two surviving children, she not only became the ancestress of the House of Orléans, which came to the French throne with Louis Philippe I, the so-called "Citizen King" from 1830 to 1848, but also became the ancestress of numerous European royal families, so she was also called the "Grandmother of Europe". Through her daughter she was the grandmother of Francis I, Holy Roman Emperor, the husband of Maria Theresa, and great-grandmother of Joseph II and Leopold II (both Holy Roman Emperors) and Marie Antoinette, the last Queen of France before the French Revolution.