Nuclear fusion
Nuclear fusion was initially pursued only in theoretical stages during World War II, when scientists on the Manhattan Project (led by Edward Teller) investigated it as a method to build a bomb. The project abandoned fusion after concluding that it would require a fission reaction to detonate. It took until 1952 for the first full hydrogen bomb to be detonated, so-called because it used reactions between deuterium and tritium. Fusion reactions are much more energetic per unit mass of fuel than fission reactions, but starting the fusion chain reaction is much more difficult.