南蛮貿易
First contact between Brazil and Japan was through Portuguese explorers who first arrived to Japan in 1543 and got foreign control of the city of Nagasaki; 43 years after Portugal founded its first colonies in Brazil. From 1543 to 1638, Portugal traded with Japan with stopovers in Brazil along the way, known as the Nanban trade. Many Japanese products were sold in Brazil and, during this time period, Portuguese traders sold Japanese slaves in Brazil. By 1638, Portuguese traders were no longer allowed to trade in Japan, however, trade continued between the Portuguese colony in Macau. Soon afterwards, Japan entered a period of isolation.