Yoshirō Mori
In December 2000, he was appointed Minister of Health and Welfare and Minister of Labor in the LDP-Liberal-Komeito coalition cabinet of Yoshirō Mori. The ministries merged in 2001, making Sakaguchi the first individual to hold the combined position of Minister of Health, Labour and Welfare. He retained this position under Junichiro Koizumi until September 2004.