Province of North Carolina
John Culpepper was born about 1761 near Wadesboro, Anson County, Province of North Carolina, the son of Sampson Culpepper (1737 Bertie County, Province of North Carolina – 1820 Wilkinson County, Georgia) and Eleanor Gilbert (April 25, 1745 Norfolk County, Virginia Colony – July 19, 1823 Wilkinson County, Georgia). John Culpeper of Albemarle, leader of Culpeper's Rebellion in 1677, was Culpepper's third great uncle.