Derby d'Italia
Marchisio continued to be first choice under Ciro Ferrara and later Alberto Zaccheroni mainly due to his versatility and consistency in midfield. During the beginning of the 2009–10 season, he had a good run of form, winning Man of the Match awards in four consecutive matches and being voted Player of the Month for September by registered members on the club website but picked up a knee injury in the loss to Palermo at the beginning of October. After surgery, he was sidelined for one month-and-a-half and made his comeback as a last minute substitute in the Champions League group stage tie away at Bordeaux on 25 November. On 5 December 2009, he scored the winner in a 2–1 home win over Internazionale in the Derby d'Italia, where he showed incredible composure to drag the ball with both feet before dinking it over the stranded Júlio César. Three days later, he set up David Trezeguet to score the opening goal of the game in the decisive Champions League 1–4 home loss against Bayern Munich. At the end of the year, he was voted Juventus Player of the Year for 2009 by fans on the club website. In the Europa League round of 16 tie against Fulham on 11 March 2010, he captained the team for the first time when David Trezeguet handed him the captain's armband after being substituted at the 62nd minute, as vice-captains Gianluigi Buffon and Giorgio Chiellini missed the match through injury and Del Piero remained an unused substitute. He scored an equalizer against Catania on the second-last away matchday to keep Juventus in a Europa League spot and, despite Juventus' dismal season, was one of the few players to escape the mass criticism from the press.