Francisco Pizarro
In 1552, Hernando married his niece, Francisca Pizarro Yupanqui (she was the daughter of Francisco Pizarro and his Inca mistress Inés Yupanqui) in Spain. Although born out of wedlock, she was legitimized by Imperial Decree. They had five children. One of their sons, Francisco Pizarro y Pizarro, married twice and had offspring, the Marqueses de La Conquista. As a result, the Pizarro line survived Hernando's death, though currently it is extinct in male line.