Brother Blood
The Brain and the new Brotherhood of Evil came into conflict with Brother Blood, whose life-restoring blood pits Brain sought to use to prolong his own life. To deal with Brother Blood's inhuman powers, the group repeatedly attacked the Titans in order to kidnap Raven and force her to aid them in defeating Brother Blood. They ultimately succeeded in kidnapping Raven with the Brain's influence and the fear manipulating power of Phobia, briefly turning Raven to the Brotherhood's side. Unfortunately, in doing so, Raven's demonic father Trigon was able to gain control over Raven's body and nearly killed both the Titans and the Brotherhood, if not for the intervention of Donna Troy (who had been teleported outside the battlefield by Warp at the start of the fight).