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Gevherhan Sultan (; 1544 – 1622) was an Ottoman princess, the daughter of Sultan Selim II (reign 1566—1574). She was the granddaughter of Suleiman the Magnificent (reign 1520–66) and Hürrem Sultan, sister of Sultan Murad III (reign 1574–95) and aunt of Sultan Mehmed III (reign 1595–1603).