ヒストン脱アセチル化酵素
Histone deacetylase 2 (HDAC2) is an enzyme that in humans is encoded by the "HDAC2" gene. It belongs to the histone deacetylase class of enzymes responsible for the removal of acetyl groups from lysine residues at the N-terminal region of the core histones (H2A, H2B, H3, and H4). As such, it plays an important role in gene expression by facilitating the formation of transcription repressor complexes and for this reason is often considered an important target for cancer therapy.