ディールス・アルダー反応
The Diels–Alder reaction was first reported in 1928 by Otto Diels and Kurt Alder; they were awarded the Nobel Prize in chemistry for their work in 1950. Since that time, use of the Diels–Alder reaction has become widespread. Conversely, DAINV does not have a clear date of inception, and lacks the comparative prominence of the standard Diels-Alder reaction. DAINV does not have a clear date of discovery, because of the difficulty that chemists had in differentiating normal from inverse electron-demand Diels-Alder reactions before the advent of modern computational methods. Much of the work in this area is attributed to Dale Boger, though other authors have published numerous papers on the subject.