Bubonic plague
Bubonic plague is a variant of the deadly flea-borne disease plague, which is caused by the enterobacteria "Yersinia pestis", that devastated human populations beginning in the 14th century. Bubonic plague is primarily spread by fleas that lived on the black rat, an animal that originated in south Asia and spread to Europe by the 6th century. It became common to cities and villages, traveling by ship with explorers. A human would become infected after being bitten by an infected flea. The first sign of an infection of bubonic plague is swelling of the lymph nodes, and the formation of buboes. These buboes would first appear in the groin or armpit area, and would often ooze pus or blood. Eventually infected individuals would become covered with dark splotches caused by bleeding under the skin. The symptoms would be accompanied by a high fever, and within four to seven days of infection, more than half the victims would die.