Санти-Куаттро-Коронати
He was named the parish priest of Sarteano, and Archpriest and Vicar-General of the Diocese of Chiusi before going to Rome to work as a legal advocate. In 1612, he was elected the Bishop of Amelia and became a "Signatory" of the Apostolic Penitentiary and served as "Governor of Rome" for eight years. On 21 October 1612, he was consecrated bishop by Giovanni Garzia Mellini, Cardinal-Priest of Santi Quattro Coronati, with Alessandro Ludovisi, Archbishop of Bologna, and Lorenzo Landi, Bishop of Fossombrone, serving as co-consecrators. In 1618, he was named Nuncio to Spain and remained there until 1621 and the Latin Patriarch of Jerusalem - a title he retained until 1645.