Red Skull
Captain America, often with teenage partner Bucky Barnes, fought and thwarted the Red Skull many times during the war. The heroes also fought the Red Skull when they were members of the Invaders. On one occasion the Red Skull captured, drugged, and brainwashed Captain America. He sent the hero to kill a high-ranking officer, but with Bucky's help Captain America broke free. The Red Skull later temporarily brainwashed three of the Invaders into serving him. The Red Skull and Captain America continued to engage in a series of skirmishes throughout the war.