Agathocles of Syracuse
Around the year 300 BC, Ptolemy I was in engaged in a round of diplomatic marriages involving his children. Theoxena was a part of his strategy by marrying Agathocles of Syracuse, a Syracusan Greek ruler of Syracuse and later king of Sicily. Theoxena married Agathocles as his third and final wife. From her marriage to Agathocles, reveals and indicates that Theoxena was a noblewoman of high status, in particular when she lived in Sicily. Little is known on her relationship with her husband and her life in Sicily. Agathocles became tyrant of Syracuse in 317 BC and declared himself Sicilian King in 304 BC.