مريم العذراء
According to the bishop of Salamis, Epiphanius, in his work "The Panarion" (AD 374–375) "Joseph became the father of James and his three brothers (Joses, Simeon, Judah) and two sisters (a Salome and a Mary or a Salome and an Anna) with James being the eldest sibling. James and his siblings were not children of Mary but were Joseph's children from a previous marriage. After Joseph's first wife died, many years later when he was eighty, "he took Mary (mother of Jesus)".