Ураба
Alonso de Ojeda and Vasco Núñez de Balboa explored the coast of Colombia in 1500 and 1501. They spent the most time in the Gulf of Urabá, where they made contact with the Cunas. The regional border was initially created in 1508 after royal decree, to separate the colonial governorships of Castilla de Oro and Nueva Andalucía, using the River Atrato as the boundary between the two goverorships.