Mycobacterium leprae
The ability of the mannose receptor to aid in pathogen internalisation is also thought to facilitate infection by "Mycobacterium tuberculosis" and "Mycobacterium leprae". These bacteria reside and multiply in macrophages, preventing formation of the phagolysosome to avoid degradation. Hence, by mediating their entrance into the macrophage, blocking the mannose receptor helps these pathogens to infect and grow in their target cell.