Rh disease
Also, in conjunction with Philip Levine's separate work which helped identify the Rh factor as a major cause of erythroblastosis fetalis, or Rh disease, he was able to help solve a major cause of infant fatality. In 1946, Dr. Wiener created the first medical procedure to combat the problem, which he called an exchange transfusion. It consisted of a complete blood transfusion for the affected baby. The method was further refined by Harry Wallerstein, a transfusionist.