Red blood cell
The "in vivo" technique is more convenient for the majority of patients since it is less time-consuming and less costly and more than 80 percent of the injected radionuclide usually binds to red blood cells with this approach. Red blood cell binding of the radioactive tracer is generally more efficient than "in vitro" labeling, and it is preferred in patients with indwelling intravenous catheters to decrease the adherence of Tc-99m to the catheter wall and increase the efficiency of blood pool labeling.