Targa Florio
Masetti acquired his first car, a 4.5-litre Fiat S57 B14 from Antonio Ascari, in which he was fourth at X Targa Florio (1919), and won the XII Targa Florio (1921). The next year, he won XIII Targa Florio in his privately entered ex-Otto Salzer 1914 Mercedes 4.5-litre 115 HP 18/100 (1922).