John II of Portugal
Ortiz came to Portugal in 1476, accompanying Castilian Princess Joanna La Beltraneja. He became an adviser to King John II of Portugal and later Manuel I, being successively appointed Bishop of Tanger (1491–1500), Bishop of Ceuta (1500–1504) and Bishop of Viseu (1505–1519). During his rule, he led a comprehensive artistic remodelling of Viseu Cathedral.