Santa Ana de Coro
Spain's colonization of mainland Venezuela started in 1522. Spain established its first permanent South American settlement in the present-day city of Cumaná. When Spanish colonists began to arrive, indigenous people lived mainly in groups as agriculturists and hunters: along the coast, in the Andean mountain range, and along the Orinoco River. In 1527, Santa Ana de Coro was founded by Juan de Ampíes, the first governor of the Spanish Empire's Venezuela Province. Coro would be the Province's capital until 1546 followed by El Tocuyo (1546–1577), until the capital was moved to Caracas in 1577 by Juan de Pimentel.