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"Neon Genesis Evangelion 64" is a fighting video game similar to games such as "" (1995). Its plot is loosely based on the anime, taking place in 2015 where 75% of Earth's population has been wiped out by alien beings known as Angels. The organization "NERV" assigns three teenage pilots—Shinji Ikari, Rei Ayanami, and Asuka Langley Soryu—to pilot a cyborg named the Evangelion in order to destroy the Angels before they eradicate the rest of the human race.