Battle of Issus
When Darius III began a military campaign against the invading army of Alexander the Great, he was accompanied by Drypetis, along with her sister, her mother, and her grandmother Sisygambis. Following the Battle of Issus in 333 BCE, Darius fled and his family was captured by Macedonian troops. Alexander personally met with the women and promised to provide dowries for Drypetis and Stateira.