Tibetan antelope
The Tibetan mastiff breed was able to adapt to the extreme highland conditions of the Tibetan Plateau very quickly, comparably to other mammals such as the yak, the Tibetan antelope, the snow leopard, and the wild boar. The Tibetan mastiff's ability to avoid hypoxia in high elevations due to its higher hemoglobin levels compared to low-altitude dogs, was due to prehistoric interbreeding with the wolves of Tibet.