Cain Velasquez
A third fight with Cain Velasquez took place on 19 October 2013 at UFC 166. Although dos Santos experienced more moments of success than in their second fight, he was still dominated by Velasquez for most of the fight. He lost via TKO at 3:09 of the fifth round after landing on his head during an attempted submission and follow up punches from Velasquez.