Electron transfer
Acetylation and succinylation of lysine residues and phosphorylation of serine and threonine residues in ETF-β have been reported in mass spectrometric analyses of posttranslational modifications P13804. Trimethylation of two lysines, Lys-200 and Lys-203, in ETF-β has been indicated to affect ETF activity. Electron transfer flavoprotein regulatory factor 1 (ETFRF1) has been identified as a protein that specifically binds ETF and this interaction has been indicated to inactivate ETF by displacing the FAD.