Jean-Guillaume de Neubourg-Wittelsbach
Cosimo did not enjoy a harmonious relationship with his elder son, Ferdinando. They disagreed about Cosimo's bigoted ideology and his monthly allowance. Cosimo married him to a Bavarian princess, Violante Beatrice. This union was exceedingly discontent, and produced no offspring. Anna Maria Luisa was the Grand Duke's favourite child. She married Johann Wilhelm, Elector Palatine, and like her brother, had no issue. Gian Gastone, Cosimo's eventual successor, despised his father and his court. Anna Maria Luisa arranged for him to marry Anna Maria Franziska of Saxe-Lauenburg, a union that produced no children.