Giuliano de' Medici
Leo X's fun-loving pontificate bankrupted Vatican coffers and accrued massive debts. From Leo's election as pope in 1513 to his death in 1521, Florence was overseen, in turn, by Giuliano de' Medici, Duke of Nemours, Lorenzo de' Medici, Duke of Urbino, and Giulio de' Medici, the latter of whom became Pope Clement VII.