Coco Solo
On 7 December, the United States entered World War II. The next day, "S-43" departed the Canadian coast for New London and Coco Solo. On 27 December, she reached the Panama Canal Zone; and, on 9 January 1942, she transited the canal to conduct a security patrol in the Pacific approaches to that vital area. Returning to Coco Solo on 2 February, she prepared for transfer to the Australia-New Zealand area.