Mandylion
Around the end of the 6th century the first references to Christian palladia start to appear. The Image of Edessa in Armenian Mesopotamia, or Mandylion, later moved to Constantinople, is one of the first and long the most famous examples. This was later credited with the failure of the Persian siege of Edessa in 544. But the image is not mentioned in the account of Procopius, writing soon after the event, and first appears as the agent of the failure in the history of Evagrius Scholasticus of about 593. Specific icons, especially those of the Virgin Mary or Virgin and Child became credited with specialist functions, with their veneration aiding against disease or other misfortunes, and the military role of palladium was an example of this.