Tranexamic acid
For those with bleeding peptic ulcers, fluid replacement with crystalloids should be given to maintain volume in the blood vessels. Haemoglobin should be maintained at greater than 7 g/dL (70 g/L) through restrictive blood transfusion because it has been associated with reduced rate of death. Glasgow-Blatchford score is useful in determining whether a person should be treated inside a hospital or as an outpatient. Intravenous PPIs can suppress stomach bleeding more quickly than oral ones. A neutral stomach pH is required to keep platelets in place and prevent clot lysis. Tranexamic acid and antifibrinolytic agents are not useful in treating peptic ulcer disease.