Gargantua and Pantagruel
The name "Gargamel" is not a Jewish name but echoes Rabelais' classic "Gargantua and Pantagruel", where the giantess Gargamelle is the mother of Gargantua. This is appropriate since Gargamel is a giant compared to the Smurfs. The word "gargamelle" in French has become a slang term for "throat".