بارتولومي دي لاس كاساس
Since its founding, the college became a focus of influence of the Early-Modern Age, in which were formed theologians, men of letters, universities's founders, bishops, king's advisers or jurists, like Bartolomé de las Casas, Melchor Cano, Luis de Granada or Francisco de Vitoria, and in which took place in 1550-1551, for example, the famous Valladolid debate, in which Friar Bartolomé de las Casas defended the indigenous peoples of the America's rights, against Juan Ginés de Sepúlveda supporter of the rights for the dominion of the conquerors towards the Indigenous, whom he considered inferior beings.