中野站
In Isumi the highways diverge, with National Route 128 continuing south along the coast towards the southern tip of the peninsula and National Route 465 heading west towards its interior, paralleling the Isumi Line. Crossing into the mountainous town of Ōtaki, the highway meets National Route 297 just to the west of the town's central district. The two highways share a brief concurrency running south through the relatively dense area, after which National Route 465 continues west, paralleling the Isumi Line to the railway's terminus at Kazusa-Nakano Station.