Khanate of Kazan
The most damaging invasions occurred in 1517, 1521 (supported by the Khanate of Kazan), 1537 (supported by the Khanate of Kazan, the Lithuanians, and the Ottoman Empire), 1552, 1555, 1570–72 (supported by Sweden and the Ottoman Empire), 1589, 1593, 1640, 1666–67 (supported by Poland–Lithuania), 1671, and 1688.