President of Uzbekistan
In 1991, Safoyev was appointed Chief Consultant and Head of Department of International Economic Relations in Presidential Administration. From 1992 until 1993, he served as the First Deputy Minister of Foreign Economic Relations. From February 1993 until February 1994, he served as the Minister of Foreign Affairs of Uzbekistan (officially established as a ministry in February 1994). In 1993-1996, Safoyev served as Ambassador of Uzbekistan to Germany, also accredited for the Netherlands and Austria. In 1996, he worked as a State Advisor to the President of Uzbekistan and in from 1996 until 2001, served as the Ambassador of Uzbekistan to the United States, also accredited for Canada. After returning to Uzbekistan, in 2001-2003 Safoyev worked as the First Deputy Minister of Foreign Affairs, from 2002 to 2003 also the special representative of the President of Uzbekistan in Afghanistan.