Spacing Guild
This resentment, coupled with Bene Gesserit orders that Paul not be allowed to father an heir with Chani, has driven Irulan to secretly drug the Fremen woman with dangerous contraceptives for years. As a result, the new Emperor and his concubine are without children. When Chani begins a special Fremen fertility diet high in melange, Irulan loses her ability to administer the contraceptives; though urged by the Bene Gesserit Reverend Mother Mohiam to chemically abort any potential fetus, Irulan protests. Irulan does, however, become part of a conspiracy against the Emperor involving the Bene Gesserit, Tleilaxu, and Spacing Guild. Paul says of her at this time: