مايكل سكوفيلد
After eight prisoners escape from the Fox River State Penitentiary, Mahone leads the investigation to capture them. Reviewing their files, he decides to concentrate his efforts on Michael Scofield, mastermind of the breakout. He tracks the escapees to Oswego, Illinois, but they manage to escape. Mahone continues to pursue Michael and his brother Lincoln Burrows (Dominic Purcell), who are able to avoid him on several occasions. While investigating a car explosion Mahone is shown to have a drug problem, swallowing pills concealed in a pen.