Latin American Episcopal Conference
On June 13, 1946, his thirty-fourth birthday, Vilela was appointed Bishop of Petrolina by Pope Pius XII. He received his episcopal consecration on the following October 27 from Bishop José Gomes da Silva, with Bishop Adalberto Accioli Sobral and Archbishop Mário de Miranda Villas-Boas serving as co-consecrators. Vilela was later promoted to Archbishop of Teresina on November 5, 1955, and attended the Second Vatican Council from 1962 to 1965. Serving as President of the Latin American Episcopal Conference from 1966 to 1972, he was named Archbishop of São Salvador da Bahia on March 25, 1971.