Cosimo III de' Medici, Grand Duke of Tuscany
Ferdinando's marriage to Vittoria della Rovere produced two children: Cosimo III de' Medici, Grand Duke of Tuscany, and Francesco Maria de' Medici, Duke of Rovere and Montefeltro. Upon Vittoria's death in 1694, her allodial possessions, the Duchies of Rovere and Montefeltro, passed to her younger son.