Tsugaru Strait
is a national highway of Japan that traverses the prefectures of Aomori and Hokkaido, as well as the Tsugaru Strait that separates them. The highway begins at an intersection with National Route 5 in Hakodate, then crosses the Tsugaru Strait on a ferry from Hakodate to Ōma, Aomori, that it shares with National Route 279, where it then travels south through eastern Aomori Prefecture, passing through the city of Mutsu before ending at an intersection with National Route 4 in Noheji.