液氢
Sulfur tetrafluoride can be used to replace a variety of functional groups with partially or fully fluorinated derivatives. Liquid hydrogen fluoride can be used as a solvent and catalyst with SF4 to selectively fluorinate alcohols. SF4's reactivity with carbonyl compounds is not enhanced in the presence of HF. Generally, only relatively acidic alcohols can be fluorinated efficiently with SF4, although amino alcohols appear to be an exception to this rule.