Cushing's syndrome
About two to three people per million are affected each year. It most commonly affects people who are 20 to 50 years of age. Women are affected three times more often than men. A mild degree of overproduction of cortisol without obvious symptoms, however, is more common. Cushing's syndrome was first described by American neurosurgeon Harvey Cushing in 1932. Cushing's syndrome may also occur in other animals including cats, dogs, and horses.