The Little Shop of Horrors
The 1960 comedy horror film "The Little Shop of Horrors" is set in Skid Row; however, the location of the 1982 musical (and its 1986 film adaptation) was moved to New York City (although the song "Skid Row (Downtown)" exists in both the play and its adaptation). "Predator 2" and some of the "Terminator" movies were also filmed in downtown Los Angeles.