Black pepper
Like many eastern spices, pepper was historically both a seasoning and a traditional medicine. Pepper appears in the Buddhist Samaññaphala Sutta, chapter five, as one of the few medicines a monk is allowed to carry. Long pepper, being stronger, was often the preferred medication, but both were used. Black pepper (or perhaps long pepper) was believed to cure several illnesses, such as constipation, insomnia, oral abscesses, sunburn, and toothaches, among others. Various sources from the fifth century onward recommended pepper to treat eye problems, often by applying salves or poultices made with pepper directly to the eye. Though current medical research has yet to confirm any treatment benefit to humans, several benefits have been shown in animal modeling experiments.