House of Borgia
Louise was born on 17 May 1500. She was Cesare Borgia's only child with his wife, Charlotte of Albret. Her paternal grandparents were Pope Alexander VI of the House of Borgia and Vannozza dei Cattanei, and her maternal grandparents were Alain I of Albret, Lord of Albret, and Françoise of Châtillon-Limoges. She had at least eleven illegitimate half-siblings from her father's relationships with other women.