Land of Punt
The intermediate hosts "Biomphalaria" snails are estimated to originate in South America 95–110 million years ago. But the parasites "Schistosoma" originated in Asia. In Africa, the progenitor species evolved into modern "S. mansoni" and "S. haematobium" around 2–5 million years ago. It reached Egypt via infected slaves and baboons from the Land of Punt through migrations that occurred possibly as early as the V Dynasty ("c". 2494–2345 BCE).