Mark Buehrle
On November 19, 2012, Mathis was traded to the Miami Marlins along with Adeiny Hechavarria, Henderson Álvarez, Yunel Escobar, Jake Marisnick, Anthony DeSclafani, and Justin Nicolino, in exchange for Mark Buehrle, Josh Johnson, José Reyes, John Buck, and Emilio Bonifacio. Mathis was expected to serve as the back-up to Rob Brantly.