Ethylene glycol
Ethylene glycol is a high-production-volume chemical; it breaks down in air in about 10 days and in water or soil in a few weeks. It enters the environment through the dispersal of ethylene glycol-containing products, especially at airports, where it is used in de-icing agents for runways and airplanes. While prolonged low doses of ethylene glycol show no toxicity, at near lethal doses (≥ 1000 mg/kg per day) ethylene glycol acts as a teratogen. "Based on a rather extensive database, it induces skeletal variations and malformations in rats and mice by all routes of exposure." This molecule has been observed in outer space.