Nikephoros III Botaneiates
John Komnenos married Anna Dalassene, the daughter of Alexios Charon, most likely in 1044. Anna, born , long outlived her husband and after his death ran the family as its undisputed matriarch. Anna became involved in conspiracies against the Doukas family, whom she never forgave for taking the throne in 1059. Later she also played a major role in the successful overthrow of Nikephoros III Botaneiates () and the rise of her son Alexios to the throne. After that, and for about fifteen years, she served as the virtual co-ruler of the empire alongside her son. She then retired to a monastery, where she died in 1100 or 1102.