Ashikaga clan
Ashikaga Yoshisue, son of Ashikaga Yoshizane, was the first to take the name of Hosokawa. Hosokawa Yoriharu, a Hosokawa of the late Kamakura period, fought for the Ashikaga clan against the Kamakura shogunate. Another, Hosokawa Akiuji, helped establish the Ashikaga shogunate.