Seishirō Itagaki
Over the course of its history particularly in the Edo period, there were several retainers of the Nanbu clan who became famous on a national scale. Narayama Sado, a clan elder ("karō") who was active during the Boshin War, was one of them; he was responsible for leading the Nanbu clan's political activity and interaction with neighboring domains. Hara Takashi, who later became Prime Minister of Japan, was another. Some 20th-century figures in Japanese politics also came from families of former Nanbu retainers; perhaps the most well known of which was Seishirō Itagaki and Hideki Tōjō.