Jorge Linares
On July 21, 2007, Jorge Linares of Venezuela defeated him by KO in the 10th round for the WBC Interim featherweight title in Las Vegas, Nevada, Nevada. After the fight with Linares, Larios was diagnosed with a minor subdural hematoma, bleeding of the brain, putting any hopes of a future boxing career in jeopardy. Larios eventually returned to boxing, but remains under medical suspension throughout the United States.