果蠅屬（學名：Drosophila）是雙翅目果蠅科的一個屬（不同於實蠅科的「果實蠅」），於1823年由瑞典昆蟲學家卡爾·弗雷德里克·法倫描述發表，其學名來自希臘文的δροσος（drosos，指露水）與 φιλος（philos，指喜愛），模式種為Drosophila funebris。本屬物種黑腹果蠅為生物學研究中重要的模式生物，廣泛用於遺傳學研究，此外擬果蠅、塞席爾果蠅、雅库巴果蝇、嗜鳳梨果蠅、擬暗果蠅、黑翅果蝇、Drosophila willistoni、Drosophila mojavensis、Drosophila virilis和Drosophila grimshawi等物種的基因組也已被完整定序，有些也被用作生物研究的模式生物。
果蠅屬已發表的物種超過1500種，但很可能是複系群，多數物種屬Drosophila和Sophophora兩亞屬，此外還有Dorsilopha、Siphlodora和Dudaica等亞屬，過去曾有學者提議將本屬限制在Sophophora亞屬的物種，並以黑腹果蠅為模式種，但未獲國際動物命名法委員會通過。本屬物種廣泛分布於世界各地，其中以熱帶地區為多，在沙漠、熱帶雨林、城市、沼澤與高山中皆有，黑腹果蠅、大果蠅和擬果蠅常出現於人類生活的環境，
北美洲的蒙大拿果蠅棲息於高海拔山區，為適應低溫的耐寒物種，分布於夏威夷的約400個物種有時被歸為一獨立屬Idiomyia。本屬物種大多以腐敗的植物或真菌基質為食，少數物種（鈴木氏果蠅）可食用新鮮果實而為害蟲，雄性個體的精子長度在動物界中算相當長的，二裂果蠅的精子伸展時長達5.8公分，超過其體長的20倍，為已知生物最長的精子 。


下属物种 本属包括以下物种：

 Drosophila abjuncta Hardy, 1965
 Drosophila abregolineata Duda, 1925
 Drosophila abron Burla, 1954
 Drosophila abure Burla, 1954
 Drosophila acadia Hsu, 1949)
 Drosophila acanthomera Tsacas, 2001
 Drosophila acanthoptera Wheeler, 1949
 Drosophila acanthos Kam & Perreira, 2003
 Drosophila acanthostoma Hardy & Kaneshiro, 1968
 Drosophila acelidota Tsacas, 2004
 Drosophila achlya Hardy, 1967
 Drosophila acroria Wheeler & Takada, 1962
 Drosophila acrostichalis Hardy, 1965
 Drosophila acrostigma Tsacas & Chassagnard, 1999
 Drosophila acuminanus Hunter, 1988
 Drosophila acutilabella Stalker, 1953
扁鼻果蝇 Drosophila (Drosophila) acutissima Okada, 1956
 Drosophila adamisa Chassagnard & Tsacas, 1997
 Drosophila adamsi Wheeler, 1959
 Drosophila addisoni Pavan, 1950
 Drosophila adiastola Hardy, 1965
 Drosophila adunca Hardy, 1965)
 Drosophila adventitia Hardy, 1965
 Drosophila (Nudidrosophila) aenicta Hardy, 1967)
 Drosophila aethostoma Hardy & Kaneshiro, 1968
阿佛果蝇 Drosophila afer Tan, Hsu & Sheng, 1949
 Drosophila affinidisjuncta Hardy, 1978
 Drosophila affinis Sturtevant, 1916
 Drosophila afoliolata Zhang & Toda, 1995
 Drosophila (Drosophila) afra Tan, Hsu & Sheng, 1949
 Drosophila agitona Hardy, 1965
 Drosophila aglaia Hardy, 1965
 Drosophila aguape Val & Marques, 1996
 Drosophila agumbensis Prakash & Reddy, 1978
 Drosophila akai Burla, 1954
 Drosophila akoko Magnacca & O'Grady, 2008
 Drosophila alafumosa Patterson & Mainland, 1943
 Drosophila alagitans Patterson & Mainland, 1943
 Drosophila alani Pipkin, 1964
 Drosophila albescens Frota-Pessoa, 1954
 Drosophila albicans Frota-Pessoa, 1954
 Drosophila albifacies Hardy, 1965
 Drosophila albincisa Meijere, 1911
 Drosophila albipalpis Katoh & Gao, 2018
 Drosophila albipes Walker, 1853
 Drosophila albirostris Sturtevant, 1921
 Drosophila albomarginata Duda, 1927
银额果蝇 Drosophila albomicans Duda, 1923
 Drosophila albonotata Meijere, 1911
 Drosophila albosetulosa Morge, 1976)
 Drosophila albovitata Sheng, Tan & Chen, 1944
 Drosophila aldrichi Patterson, 1940
 Drosophila alei Brncic, 1962
 Drosophila alexanderae Pipkin, 1964
 Drosophila alexandrei Cordeiro, 1951
 Drosophila alfari Sturtevant, 1921
 Drosophila algonquin Sturtevant & Dobzhansky, 1936
 Drosophila alladian Burla, 1954
 Drosophila allochroa Tsacas, 2002
 Drosophila aloma Tsacas, 1981
 Drosophila alpina Burla, 1948
 Drosophila alsinis Basden, 1962
 Drosophila alsophila Hardy & Kaneshiro, 1971
 Drosophila alternolineata Duda, 1925
 Drosophila altiplanica Brncic & Koref Santibanez, 1957
 Drosophila altissima Tsacas, 1980
 Drosophila altukhovi Imasheva, Lazebny, Cariou, David & Tsacas, 1994
 Drosophila amaguana Vela & Rafael, 2003
 Drosophila ambigua Pomini, 1940
 Drosophila ambochila Hardy & Kaneshiro, 1971
 Drosophila americana Spencer, 1938
 Drosophila amita Hardy, 1965)
 Drosophila amphibolos Tsacas & Chassagnard, 1990
 Drosophila amplipennis Malloch, 1934
 Drosophila amydrospilota Hardy, 1965
 Drosophila analis Macquart, 1844
 Drosophila analspina Singh & Negi, 1995
 Drosophila analspinii Singh & Negi, 1992
 Drosophila analspinula Lin & Wheeler, 1977
嗜凤梨果蝇 Drosophila ananassae Doleschall, 1858
 Drosophila anapuu Magnacca & O'Grady, 2009
 Drosophila anceps Patterson & Mainland, 1944
 Drosophila ancora Okada, 1968
 Drosophila ancyla Hardy, 1965
 Drosophila (Sophophora) andamanensis Gupta & Ray-Chaudhuri, 1970
圆尾果蝇 Drosophila (Drosophila) angor Lin & Ting, 1971
 Drosophila angularis Okada, 1956
 Drosophila angustibucca Duda, 1925
 Drosophila anisoctena Tsacas, 1980
 Drosophila annularis Sturtevant, 1916
 Drosophila (Drosophila) annulimanus Duda, 1927
竹节果蝇 Drosophila (Drosophila) annulipes Duda, 1923
 Drosophila annulosa Vilela & Bachli, 1990
 Drosophila anomalata McEvey & Schiffer, 2015
 Drosophila anomalipes Grimshaw, 1901
 Drosophila anomelani Reddy & Krishnamurthy, 1973
 Drosophila anoplostoma Hardy & Kaneshiro, 1968
 Drosophila antecedens Kam & Perreira, 2003
 Drosophila anthrax Hardy, 1965
反里果蝇 Drosophila (Lordiphosa) antillaria Okada, 1984
 Drosophila antillea Heed, 1962
 Drosophila antioquia Vilela & Bachli, 2000
 Drosophila antonietae Tidon-Sklorz & Sene, 2001
 Drosophila apectinata Duda, 1931
 Drosophila apicalis Hardy, 1977
 Drosophila apicespinata Zhang & Gan, 1986
 Drosophila apicipuncta Hardy, 1965
 Drosophila apicisetae Hardy, 1965
 Drosophila apiki Magnacca & O'Grady, 2009
 Drosophila aplophallata Zhang & Toda, 1995
 Drosophila apodasta Hardy, 1965
 Drosophila apodemata Okada & Carson, 1983
 Drosophila apoxyloma Hardy, 1965
 Drosophila appendiculata Malloch, 1934
 Drosophila aquila Hardy, 1965
 Drosophila aracataca Vilela & Val, 1983
 Drosophila aracea Heed & Wheeler, 1957
 Drosophila aragua Vilela & Pereira, 1982
 Drosophila araicas Pavan & Nacrur, 1950
 Drosophila araiotrichia Hardy, 1965
 Drosophila arane Hunter, 1992
 Drosophila arapuan Cunha & Pavan, 1947
 Drosophila ararama Pavan & Cunha, 1947
 Drosophila arassari Cunha & Frota-Pessoa, 1947
 Drosophila araucana Brncic, 1957
 Drosophila arauna Pavan & Nacrur, 1950
 Drosophila arawakana Heed, 1962
 Drosophila arboloco Hunter, 1979
 Drosophila arcosae Vela & Rafael, 2001
 Drosophila (Idiomyia) arcuata Hardy, 1965)
 Drosophila argenteifrons Wheeler, 1954
 Drosophila arizonae Ruiz, Heed & Wasserman, 1990
 Drosophila artecarina Takada & Momma, 1975
 Drosophila artigena Hardy, 1965
日奈氏果蝇 Drosophila asahinai Okada, 1964
 Drosophila ashburneri Tsacas, 1984
 Drosophila asketostoma Hardy, 1965
漂水果蝇 Drosophila (Drosophila) asper Lin & Ting, 1971
 Drosophila assita Hardy & Kaneshiro, 1969
 Drosophila asticta Tsacas, 2004
 Drosophila atacamensis Brncic & Wheeler, 1987
 Drosophila atalaia Vilela & Sene, 1982
 Drosophila athabasca Sturtevant & Dobzhansky, 1936
 Drosophila atra Walker, 1853
 Drosophila atrata Burla & Pavan, 1953
 Drosophila atrifacies Hardy & Kaneshiro, 2001
 Drosophila atrimentum Hardy & Kaneshiro, 1971
 Drosophila atripex Bock & Wheeler, 1972
 Drosophila atrolineata Dobzhansky & Pavan, 1943
 Drosophila atroscutellata Hardy, 1967
 Drosophila attenuata Hardy, 1965
 Drosophila attigua Hardy & Kaneshiro, 1969
 Drosophila audientis Lin & Ting, 1971
 Drosophila augonoto Pavan, 1952
金头果蝇 Drosophila (Lordiphosa) aurantifrons Okada, 1984
白颜果蝇 Drosophila auraria Peng, 1937
 Drosophila aurea Patterson & Mainland, 1944
 Drosophila aureata Wheeler, 1957
 Drosophila (Drosophila) aureopallescens Pipkins
 Drosophila auriculata Toda, 1988
 Drosophila (Drosophila) australis Malloch
南方水果果蝇 Drosophila austroheptica Tsaur & Lin, 1991
 Drosophila austrosaltans Spassky, 1957
 Drosophila avicennai Maca, 1988
 Drosophila ayauma Penafiel-Vinueza & Rafael, 2019
 Drosophila azteca Sturtevant & Dobzhansky, 1936
 Drosophila badia Hardy, 1965
 Drosophila badia Lin & Wheeler, 1977
 Drosophila bageshwarensis Singh & Dash, 1994
 Drosophila bahunde Tsacas, 1980
 Drosophila bai Watabe & Liang, 1990
 Drosophila baimaii Bock & Wheeler, 1972
 Drosophila bakondjo Tsacas, 1980
 Drosophila (Sophophora) bakoue Tascas & Lachaise
 Drosophila baliensis Suwito & Watabe, 2010
 Drosophila balioptera Hardy, 1965
 Drosophila balneorum Sturtevant, 1927
 Drosophila balteata Bergroth, 1894
 Drosophila bamboovesci Lin & Wheeler, 1977
 Drosophila bandeirantorum Dobzhansky & Pavan, 1943
 Drosophila bandeiratorum Dobzhansky & Pavan, 1943
 Drosophila barbarae Bock & Wheeler, 1972
 Drosophila barbata Magnacca & O'Grady, 2009
 Drosophila barobusta Suwito & Watabe, 2010
 Drosophila barutani Watabe & Liang, 1990
 Drosophila basimacula Hardy, 1965
 Drosophila basiprojecta Zhang, 2004)
 Drosophila basisetae Hardy & Kaneshiro, 1968
 Drosophila basisetosa Hardy, 1965
 Drosophila batmani Vilela & Bachli, 2005
 Drosophila baucipyga Lachaise & Chassagnard, 2001
 Drosophila beardsleyi Hardy, 1965
 Drosophila bedicheki Heed & Russell, 1971
美丽果蝇 Drosophila bella Lin & Ting, 1971
 Drosophila belladunni Heed & Krishnamurthy, 1959
 Drosophila beppui Toda & Peng, 1989
 Drosophila berryi Cockerell, 1923
 Drosophila bhagamandalensis Muniyappa, Reddy & Krishnamurthy, 1981
 Drosophila biarmipes Malloch, 1924
 Drosophila biauraria Bock & Wheeler, 1972
 Drosophila bicondyla Hardy, 1965
 Drosophila bicornuta Bock & Wheeler, 1972
 Drosophila bifasciata Pomini, 1940
 Drosophila bifidiprocera Zhang & Gan, 1986
 Drosophila bifilum Frota-Pessoa, 1954
二裂果蝇 Drosophila bifurca Patterson & Wheeler, 1942
 Drosophila bifurcada Hunter, 1992
 Drosophila bimorpha Singh & Gupta, 1981
 Drosophila binocularis Zhang, 2008
 Drosophila biordinata Singh, Sodhi, Gupta & Lata, 1985
双梳果蝇 Drosophila bipectinata Duda, 1923
 Drosophila bipolita Hardy, 1965
 Drosophila bipunctata Patterson & Mainland, 1943
 Drosophila birchii Dobzhansky & Mather, 1961
 Drosophila biseriata Hardy, 1965
 Drosophila bisetata Toda, 1988
 Drosophila (Drosophila) bishtii Singh & Negi, 1992
 Drosophila bivibrissae Toda, 1988
 Drosophila bizonata Kikkawa & Peng, 1938
 Drosophila blanda Statz, 1940
 Drosophila blumelae Pipkin & Heed, 1964
 Drosophila bocainensis Pavan & Cunha, 1947
 Drosophila (Sophophora) bocainoides Carson, 1954
包克氏果蝇 Drosophila bocki Baimai, 1979
 Drosophila bocqueti Tsacas & Lachaise, 1974
 Drosophila bodemannae Pipkin & Heed, 1964
 Drosophila bogneri Okada, 1986
 Drosophila boletina Duda, 1927
 Drosophila boliviana Duda, 1927
 Drosophila boliviensis Duda, 1927
 Drosophila bomarea Hunter, 1979
 Drosophila bondarenkoi Sidorenko, 1993
 Drosophila boraceia Vilela & Val, 2004
 Drosophila borborema Vilela & Sene, 1977
 Drosophila borealis Patterson, 1952
 Drosophila borusta 
 Drosophila bostrycha Hardy, 1965
 Drosophila brachynephros Okada, 1956
 Drosophila brachytarsa Chassagnard & Tsacas, 1997
 Drosophila brahmagiriensis Muniyappa, Reddy & Krishnamurthy, 1981
 Drosophila breuerae Rocha, 1971
 Drosophila brevicarinata Patterson & Wheeler, 1942
 Drosophila brevicilia Hardy, 1965
 Drosophila brevina Wheeler, 1981
 Drosophila brevis Walker, 1853
 Drosophila brevissima Hardy, 1965
 Drosophila brevitabula Zhang & Toda, 1992
 Drosophila brevitarsus Hardy, 1965
 Drosophila bridwelli Hardy, 1965
 Drosophila bridwellius Hardy, 1965
 Drosophila briegeri Pavan & Breuer, 1954
 Drosophila brindavani Sajjan & Krishnamurthy, 1972
 Drosophila brncici Hunter & Hunter, 1964
 Drosophila bromeliae Sturtevant, 1921
 Drosophila bromelioides Pavan & Cunha, 1947
 Drosophila brunettii Chaudhuri & Mukherjee, 1941
 Drosophila brunneicrus Hardy & Kaneshiro, 2001
 Drosophila brunneifrons Hardy, 1965
 Drosophila brunneisetae Hardy, 1965
 Drosophila bunnanda Schiffer & McEvey, 2006
 Drosophila (Sophophora) burlai Tscas & Lachaise
 Drosophila burmae Toda, 1986
巴氏果蝇 Drosophila busckii Coquillett, 1901
 Drosophila buzzatii Patterson & Wheeler, 1942
 Drosophila caccabata Hardy, 1965
 Drosophila calceolata Duda, 1926
 Drosophila calidata Takada, Beppu & Toda, 1979
 Drosophila californica Sturtevant, 1923
 Drosophila calloptera Schiner, 1868
 Drosophila camargoi Dobzhansky & Pavan, 1950
 Drosophila camaronensis Brncic, 1957
 Drosophila cameraria Haliday
 Drosophila cameroonensis Grimaldi & Jones, 2020
 Drosophila campylophalla Tsacas, 2006
 Drosophila canadiana Takada & Yoon, 1989
 Drosophila canalinea Patterson & Mainland, 1944
 Drosophila canalinioides Wheeler, 1957
 Drosophila canavalia Magnacca & O'Grady, 2008
 Drosophila canescens Duda, 1927
 Drosophila canipolita Hardy, 1965
 Drosophila canuta Hardy, 1965
 Drosophila capillata Lin & Wheeler, 1977
 Drosophila capitata Hardy, 1965
 Drosophila capnoptera Patterson & Mainland, 1944
 Drosophila caponei Pavan & Cunha, 1947
 Drosophila capricorni Dobzhansky & Pavan, 1943
 Drosophila carablanca Hunter, 1979
 Drosophila carbonaria Patterson & Wheeler, 1942
 Drosophila carcinophila Wheeler, 1960
 Drosophila cardami Duda, 1936
 Drosophila cardini Sturtevant, 1916
 Drosophila cardinoides Dobzhansky & Pavan, 1943
 Drosophila caribiana Heed, 1962
 Drosophila carioca Vilela & Bachli, 2004
 Drosophila cariouae Tsacas, 1985
 Drosophila caripe Vilela & Bachli, 2000
 Drosophila carlosvilelai Vela & Rafael, 2001
 Drosophila carnosa Hardy, 1965
 Drosophila carolinae Vilela, 1983
 Drosophila carrolli Gompel & Kopp, 2018
 Drosophila carsoni Wheeler, 1957
 Drosophila cathara Tsacas, 2004
 Drosophila cauverii Muniyappa, Reddy & Prakash, 1982
 Drosophila caxarumi Penafiel-Vinueza & Rafael, 2018
 Drosophila caxiuana Gottschalk, Martins, Praxedes & Medeiros, 2012
 Drosophila cellarum Robineau-Desvoidy, 1830)
 Drosophila ceratostoma Hardy, 1967
 Drosophila cestri Brncic, 1978
 Drosophila chaetocephala Hardy & Kaneshiro, 1979
 Drosophila chaetopeza Hardy, 1965
 Drosophila (Drosophila) chamundiensis Sajjan & Krishnamurthy, 1972
 Drosophila changuinolae Wheeler & Magalhaes, 1962
交力坪果蝇 Drosophila (Lordiphosa) chaolipinga Okada, 1984
 Drosophila charmadensis Gowda & Krishnamurthy, 1972
 Drosophila chauvacae Tsacas, 1984
 Drosophila cheda Tan, Hsu & Sheng, 1949
 Drosophila cheongi Takada & Momma, 1975
 Drosophila chicae Hardy & Kaneshiro, 2001
 Drosophila chichu Penafiel-Vinueza & Rafael, 2019
 Drosophila chimera Kam & Perreira, 2003
 Drosophila chisaca Hunter, 1988
 Drosophila choachi Hunter, 1992
 Drosophila chocolata Yassin & David, 2019
 Drosophila ciliaticrus Hardy, 1965
 Drosophila cilifemorata Hardy, 1965
 Drosophila cilifera Hardy & Kaneshiro, 1968
 Drosophila ciliotarsa Gupta & Gupta, 1990
 Drosophila cilitarsis Hering, 1940
 Drosophila circumdata Duda, 1926
 Drosophila clara Hardy & Kaneshiro, 2001
 Drosophila clarinervis Toda, 1986
 Drosophila clavata Hardy, 1965
 Drosophila (Drosophila) clavisetae Hardy, 1967)
 Drosophila clavitibia Hardy, 1965
 Drosophila claytonae Hardy & Kaneshiro, 1969
 Drosophila clydonia Hardy, 1965
 Drosophila cnecopleura Hardy, 1965
 Drosophila coffeata Williston, 1896
 Drosophila coffeina Schiner, 1868
 Drosophila cogani Tsacas & Disney, 1974
 Drosophila cognata Grimshaw, 1901
 Drosophila coliforae Makino & Mizuno, 1950
 Drosophila colmenares Hunter, 1988
 Drosophila colobos Tsacas, 2004
 Drosophila colorata Walker, 1849
 Drosophila comatifemora Hardy, 1965
 Drosophila combinatus Singh, 1974
 Drosophila comoe Burla, 1954
 Drosophila comorensis Tsacas, 1997
 Drosophila comosa Wheeler, 1968
扁头果蝇 Drosophila (Drosophila) compressiceps Duda, 1923
 Drosophila confertidentata Zhang, Li & Feng, 2006
 Drosophila conformis Hardy, 1965
 Drosophila confutata Hardy, 1965
 Drosophila conjectura Hardy, 1965
 Drosophila conspicua Grimshaw, 1901
 Drosophila constricta Okada & Carson, 1983
 Drosophila contorta Hardy, 1965
 Drosophila converga Heed & Wheeler, 1957
 Drosophila coonorensis Reddy & Krishnamurthy, 1973
 Drosophila cordata Sturtevant, 1942
 Drosophila cordeiroi Brncic, 1978
 Drosophila cornigera Zetterstedt, 1847
 Drosophila cornixa Takada, Momma & Shima, 1973
 Drosophila cornutitarsus Hardy & Kaneshiro, 1979
 Drosophila coroica Wasserman, 1962
 Drosophila cosanga Ramos-Guillin & Rafael, 2017
 Drosophila couturieri Tsacas, 2006
 Drosophila cracens Hardy, 1965
 Drosophila craddockae Kaneshiro & Kambysellis, 1999
 Drosophila crassa Patterson & Mainland, 1944
 Drosophila crispipennis Okada & Carson, 1983
 Drosophila crossoptera Wheeler & Takada, 1962
 Drosophila crucigera Grimshaw, 1902
 Drosophila crucigeraur Grimshaw
 Drosophila cruzloma Llangari Arizo & Rafael, 2018
 Drosophila (Sophophora) cryptica De & Gupta, 1996
 Drosophila cryptica Hardy & Kaneshiro, 2001
 Drosophila cuaso Bachli, Vilela & Ratcov, 2000
 Drosophila cuauhtemoci Felix & Dobzhansky, 1976
 Drosophila cubicivittata Okada, 1966
 Drosophila cumanda Llangari Arizo & Rafael, 2018
 Drosophila cundinamarca Vilela & Bachli, 2000
 Drosophila curiosa Hardy & Kaneshiro, 2001
 Drosophila curta Chassagnard & Tsacas, 1997
 Drosophila curticilia Hardy, 1965
 Drosophila curtitarsis Hardy & Kaneshiro, 2001
 Drosophila curvapex Frota-Pessoa, 1954
 Drosophila curvata Hardy, 1977
弯毛果蝇 Drosophila (Drosophila) curvicapillata Duda, 1923
 Drosophila curviceps Okada & Kurokawa, 1957
 Drosophila curvispina Watabe & Toda, 1984
 Drosophila curvitibia Hardy, 1965
 Drosophila cuyuja Guillin & Rafael, 2015
 Drosophila cuzcoica Duda, 1927
 Drosophila cyrtoloma Hardy, 1969
 Drosophila dacunhai Mourao & Bicudo, 1967
不倒翁果蝇 Drosophila daruma Okada, 1956
 Drosophila dasycnemia Hardy, 1965
 Drosophila davidgrimaldii Vilela & Bachli, 1990
 Drosophila davidi Tsacas, 1975
 Drosophila debilis Walker, 1849
 Drosophila decemseriata Hendel, 1936
 Drosophila decolor Tsacas & Chassagnard, 1994
 Drosophila deflecta Malloch & McAtee, 1924
 Drosophila deltaneuron Bryan, 1938
 Drosophila demipolita Hardy, 1965
 Drosophila denieri Blanchard, 1938
 Drosophila denotata Hardy, 1965
 Drosophila denticulata Bock & Wheeler, 1972
 Drosophila dentilabia Magnacca & O'Grady, 2009
 Drosophila dentissima Bock & Wheeler, 1972
 Drosophila desallei Magnacca & O'Grady, 2009
 Drosophila desavrilia Tsacas, 1985
 Drosophila desbaratabaile Hunter, 1979
 Drosophila desertorum Wasserman, 1962
 Drosophila diama Burla, 1954
 Drosophila diamphidia Hardy, 1965)
 Drosophila (Idiomyia) diamphidiopoda Hardy, 1965)
 Drosophila dianensis Gao & Watabe, 2003
 Drosophila dicropeza Hardy & Kaneshiro, 1979
 Drosophila dictena Tsacas & Chassagnard, 1992
 Drosophila differens Hardy & Kaneshiro, 1975
 Drosophila difficilis Wiedemann, 1830)
 Drosophila diffusa Hardy, 1965
 Drosophila digressa Hardy & Kaneshiro, 1968
 Drosophila dilacerata Becker, 1919
 Drosophila diminuens Hardy, 1965
 Drosophila dimitra Tsacas, 1981
 Drosophila dimitroides Chassagnard & Tsacas, 1997
 Drosophila diplacantha Tsacas & David, 1978
 Drosophila diplochaeta Tsacas, 2003
 Drosophila discreta Hardy & Kaneshiro, 1968
 Drosophila disjuncta Hardy, 1965
 Drosophila dissimilis Katoh & Gao, 2018
 Drosophila dissita Hardy, 1965
 Drosophila disticha Hardy, 1965
 Drosophila distinguenda Hardy, 1965
 Drosophila divaricata Hardy & Kaneshiro, 1971
 Drosophila dives Hardy & Kaneshiro, 2001
 Drosophila divisa Duda, 1927
 Drosophila dobzhanskii Patterson, 1943
 Drosophila dolichotarsis Hardy, 1967
 Drosophila dolomata Hardy, 1965
 Drosophila dominicana Ayala, 1965
 Drosophila dominici Dwivedi, 1982
 Drosophila dorisvelai Vela & Rafael
 Drosophila dorsalis Walker, 1865
 Drosophila dorsigera Hardy, 1965
 Drosophila dorsivitta Walker, 1861
 Drosophila dorsociliata Hardy, 1965
 Drosophila dossoui Chassagnard, 1991
 Drosophila dracaenae Hardy, 1965
 Drosophila dreyfusi Dobzhansky & Pavan, 1943
 Drosophila dumalis Hardy, 1965
 Drosophila dumuya Burla, 1954
 Drosophila dunni Townsend & Wheeler, 1955
 Drosophila dyaramankana Burla, 1954
 Drosophila dyula Burla, 1954
 Drosophila echinostoma Kam & Perreira, 2003
 Drosophila ecuatoriana Vela & Rafael, 2003
 Drosophila editinares Okada, 1966
牵牛花果蝇 Drosophila elegans Bock & Wheeler, 1972，异名：Drosophila elegans Statz, 1940
 Drosophila eleonorae Tosi, Martins, Vilela & Pereira, 1990
 Drosophila elliptica Sturtevant, 1942
 Drosophila ellisoni Vilela, 1983
 Drosophila (Drosophila) elongata Sturtevant, 1927
 Drosophila emarginata Sturtevant, 1942
 Drosophila eminentiula Zhang & Shi, 1995
内鳃果蝇 Drosophila endobranchia Carson & Wheeler, 1968
 Drosophila engyochracea Hardy, 1965
 Drosophila enhydrobia Bachli & Tsacas, 2005
 Drosophila eniwae Takada, Beppu & Toda, 1979
 Drosophila enoplotarsus Hardy, 1965
 Drosophila (Idiomyia) entrichocnema Hardy, 1965)
 Drosophila eohydei Wasserman, 1962
 Drosophila epiobscura Parshad & Duggal, 1967
 Drosophila eprocessata Zhang & Toda, 1995
 Drosophila equinoxialis Dobzhansky, 1946
 Drosophila ercepeae Tsacas & David, 1975
 Drosophila erebopis Tsacas, 2004
 Drosophila erecta Tsacas & Lachaise, 1974
 Drosophila eremophila Wasserman, 1962
 Drosophila eskoi Lakovaara & Lankinen, 1974
细针果蝇 Drosophila eugracilis Bock & Wheeler, 1972
 Drosophila eumecothrix Hardy, 1965
 Drosophila euneohydei Zelentsova Poluektova, Mnjoian, Lyozin, Veleikodvorskaya, Zhivotovsky, Kidwell & Evgen'ev, 1999
 Drosophila eupyga Tsacas, 1981
 Drosophila euronotus Patterson & Ward, 1952
 Drosophila eurypeza Hardy, 1965
 Drosophila excita Giglio-Tos, 1893
 Drosophila (Sophophora) exiguitata Takada, Momma & Shima, 1973)
 Drosophila eximia Hardy, 1965)
 Drosophila expansa Hardy, 1965
 Drosophila ezoana Takada & Okada, 1957
 Drosophila facialba Heed & Wheeler, 1957
 Drosophila facialis Adams, 1905
 Drosophila fairchildi Pipkin & Heed, 1964
 Drosophila falleni Wheeler, 1960
 Drosophila fasciata Meigen, 1830
 Drosophila fasciculisetae Hardy, 1965
 Drosophila fascigera Hardy & Kaneshiro, 2001
 Drosophila fasciola Williston, 1896
 Drosophila fascioloides Dobzhansky & Pavan, 1943
 Drosophila fastigata Hardy, 1965
 Drosophila felix Dobzhansky, 1976
 Drosophila fengkaiensis Zhang, Chen, Peng & Lin, 1996
 Drosophila (Sophophora) fengkainensis Chen, 2008
 Drosophila ferruginea Becker, 1919
嗜榕果蝇 Drosophila ficusphila Kikkawa & Peng, 1938
 Drosophila fima Burla, 1954
 Drosophila flava Meigen
 Drosophila flavibasis Hardy, 1965
 Drosophila flavicauda Toda, 1991
 Drosophila flaviceps Grimshaw, 1901
 Drosophila flavimedifemur Zhang & Toda, 1988
 Drosophila flavisternum Hardy, 1965
 Drosophila flavitibiae Toda, 1986
 Drosophila flavohirta Malloch, 1924
 Drosophila flavolineata Duda, 1927)
 Drosophila flavomontana Patterson, 1952
 Drosophila flavopilosa Frey, 1918
 Drosophila flavopinicola Wheeler, 1954
 Drosophila flavopleuralis Takada, Momma & Shima, 1973
 Drosophila flavorepleta Patterson & Pavan, 1952
 Drosophila flexa Loew, 1866
 Drosophila flexipes Hardy & Kaneshiro, 1968
 Drosophila florae Sturtevant, 1916
 Drosophila flumenicola Watabe & Peng, 1991
 Drosophila fluminensis Vilela & Bachli, 2004
 Drosophila fluvialis Toda & Peng, 1989
 Drosophila fontdevilai Vela & Rafael, 2001
 Drosophila forcipata Collin, 1952)
 Drosophila forficata Hardy & Kaneshiro, 1979
 Drosophila formella Hardy & Kaneshiro, 1972
台湾果蝇 Drosophila formosana Duda, 1926
 Drosophila fraburu Burla, 1954
 Drosophila fragilis Wheeler, 1949
 Drosophila franii Hunter, 1988
 Drosophila freidbergi Grimaldi & Jones, 2020
 Drosophila freilejoni Hunter, 1979
 Drosophila freiremaiai Vilela & Bachli, 2000
 Drosophila freycinetiae Hardy, 1965
 Drosophila frolovae Wheeler, 1949
 Drosophila fronto Walker, 1853
 Drosophila frotapessoai Vilela & Bachli, 1990
 Drosophila fruhstorferi Duda, 1924
 Drosophila fulgida Hardy & Kaneshiro, 2001
 Drosophila fulvalineata Patterson & Wheeler, 1942
 Drosophila fulvimacula Patterson & Mainland, 1944
 Drosophila fulvimaculoides Wasserman & Wilson, 1957
 Drosophila fulvus Lin & Wheeler, 1977
 Drosophila fumifera Wheeler & Takada, 1964
 Drosophila fumipennis Duda, 1925
 Drosophila fumocalloptera Pavan, 1952
 Drosophila fundita Hardy, 1965
 Drosophila fundomaculata Duda, 1925
 Drosophila funebris Fabricius, 1787
 Drosophila fungicola Hardy, 1965
 Drosophila (Drosophila) fungiperda Hardy, 1965
 Drosophila furcatarsus Hardy & Kaneshiro, 1979
 Drosophila furva Hardy, 1965
 Drosophila furvifacies Hardy, 1965
 Drosophila fusca Coquillett, 1900
 Drosophila fuscicostata Okada, 1966
 Drosophila fuscifrons Hardy, 1965
 Drosophila fuscipennis Duda, 1927
 Drosophila fuscoamoeba Bryan, 1934
 Drosophila fuscoapex Hardy, 1965
 Drosophila fuscolineata Duda, 1925
 Drosophila fusticula Hardy, 1965
 Drosophila fustiformis Zhang & Liang, 1993
 Drosophila fusus Okada, 1988
 Drosophila fuyamai Toda, 1991
 Drosophila gagne Kam & Perreira, 2003
 Drosophila gangotrii Muniyappa & Reddy, 1981
 Drosophila gani Liang & Zhang, 1990
 Drosophila gapudi Ruiz-Fiegalan, 2003
 Drosophila gasici Brncic, 1957
 Drosophila gata Lachaise & Chassagnard, 2001
 Drosophila gaucha Jaeger & Salzano, 1953
 Drosophila (Idiomyia) gemmula Hardy, 1965)
 Drosophila gentica Wheeler & Takada, 1962
 Drosophila gibberosa Patterson & Mainland, 1943
 Drosophila gibbinsi Aubertin, 1937
 Drosophila gigantea Hsu, 1949)
 Drosophila gigas Duda, 1925
 Drosophila gilvilateralis Hardy, 1965
 Drosophila giriensis Prakash & Reddy, 1977
 Drosophila glabriapex Hardy & Kaneshiro, 1968
 Drosophila gladius Magnacca & O'Grady, 2009
 Drosophila gorokaensis Okada & Carson, 1982
 Drosophila (Drosophila) goureaui Hardy & Kaneshiro
 Drosophila gouveai Tidon-Sklorz & Sene, 2001
 Drosophila gracilipalpis Katoh & Gao, 2018
 Drosophila gracilipalpus Katoh & Gao, 2018
 Drosophila gracilitas Lin & Wheeler, 1977
 Drosophila gradata Hardy & Kaneshiro, 1968
 Drosophila greeni Bock & Wheeler, 1972
 Drosophila greerae Pipkin & Heed, 1964
 Drosophila grimshawi Oldenberg, 1914
 Drosophila griseicollis Becker, 1919
 Drosophila griseolineata Duda, 1927
 Drosophila guacamaya Bachli & Vilela, 2002
 Drosophila guacamayos Ramos-Guillin & Rafael, 2017
 Drosophila guanche Monclus, 1977
 Drosophila guangdongensis Toda & Peng, 1989
 Drosophila guaraja King, 1947
 Drosophila guaru Dobzhansky & Pavan, 1943
 Drosophila guayllabambae Rafael & Arcos, 1988
 Drosophila gubleri Hardy, 1967
 Drosophila gundensis Prakash & Reddy, 1977
 Drosophila gunungcola Sultana, Kimura & Toda, 1999
 Drosophila guptai Dwivedi, 1979
 Drosophila guttifera Walker, 1849
 Drosophila gymnobasis Hardy & Kaneshiro, 1971
 Drosophila gymnophallus Hardy & Kaneshiro, 1975
 Drosophila halapepe Magnacca & O'Grady, 2008
 Drosophila haleakalae Grimshaw, 1901
 Drosophila hamatofila Patterson & Wheeler, 1942
 Drosophila hamifera Hardy & Kaneshiro, 1968
 Drosophila hanaulae Hardy, 1969
 Drosophila hansoni Pipkin, 1964
 Drosophila hansonioides Pipkin, 1966
 Drosophila hawaiiensis Grimshaw, 1901
 Drosophila hayashii Okada, 1948
 Drosophila heedi Hardy & Kaneshiro, 1971
 Drosophila hei Watabe & Peng, 1991
 Drosophila helvetica Burla, 1948
 Drosophila hemianthrax Hardy & Kaneshiro, 2001
 Drosophila (Drosophila) hemipeza Hardy, 1965)
 Drosophila hendeli Vilela & Bachli, 1990
 Drosophila hermioneae Vilela, 1983
 Drosophila heterobristalis Tan, Hsu & Sheng, 1949
 Drosophila heteroneura Perkins, 1910)
 Drosophila hexachaetae Hardy, 1965
 Drosophila hexaspina Singh & Dash, 1994
 Drosophila hexastigma Patterson & Mainland, 1944
 Drosophila hexastriata Tan, Hsu & Sheng, 1949
 Drosophila hirticoxa Hardy, 1965
 Drosophila hirtipalpus Hardy & Kaneshiro, 1968
 Drosophila hirtipes Lamb, 1914
 Drosophila hirtiscutellata Sturtevant, 1927
 Drosophila hirtitarsus Hardy, 1965
 Drosophila hirtitbia Hardy, 1965
 Drosophila hirtitibia Hardy, 1965
 Drosophila hirtominuta Bachli, 1988
 Drosophila histrio Meigen, 1830
 Drosophila hitam Suwito & Watabe, 2010
 Drosophila hollisae Vilela & Pereira, 1992
乌凤山果蝇 Drosophila (Drosophila) hoozani Duda, 1923
 Drosophila huancavilcae Rafael & Arcos, 1989
 Drosophila huangshaenensis Watabe, 2008
 Drosophila huayla Pilar, Pilares & Vasquez, 1988
 Drosophila hubeiensis Sperlich & Watabe, 1997
 Drosophila huckinsi Etges & Heed, 2001
 Drosophila huichole Etges & Heed, 2001
 Drosophila huilliche Brncic, 1957
 Drosophila humeralis Grimshaw, 1901
 Drosophila hyalipennis Duda, 1927
海德氏果蝇 Drosophila hydei Sturtevant, 1921
 Drosophila hydroessa Bachli & Tsacas, 2005
 Drosophila hypandrilata Grimaldi & Jones, 2020
 Drosophila hyperpolychaeta Okada, 1988
雄黑果蝇 Drosophila hypocausta Osten Sacken, 1882
 Drosophila hypomelana Okada & Carson, 1983
 Drosophila hystricosa Hardy & Kaneshiro, 1969
 Drosophila ichinosei Zhang & Toda, 1995
 Drosophila icteroscuta Wheeler, 1949
 Drosophila ifestia Tsacas, 1984
 Drosophila iki Bryan, 1934
 Drosophila illata Walker, 1860
 Drosophila illota Williston, 1896
 Drosophila illusiopolita Hardy, 1965
 Drosophila imaii Moriwaki & Okada, 1967
 Drosophila imitator Hardy, 1965
 Drosophila immacularis Okada, 1966
伊米果蝇 Drosophila immigrans Sturtevant, 1921
 Drosophila imparisetae Hardy, 1965
 Drosophila improcera Hardy, 1965
 Drosophila impudica Duda, 1927
 Drosophila inca Dobzhansky & Pavan, 1943
 Drosophila inciliata Hardy & Kaneshiro, 1968
 Drosophila incognita Hardy, 1965
 Drosophila incompleta Hardy, 1965
 Drosophila incompta Wheeler & Takada, 1962
 Drosophila incongruens Magnacca & O'Grady, 2009
 Drosophila inebria Kam & Perreira, 2003
 Drosophila inedita Hardy, 1965
 Drosophila inexspectata Tsacas, 1988
 Drosophila infuscata Grimshaw, 1901
 Drosophila ingens Hardy & Kaneshiro, 1971
 Drosophila ingrata Haliday, 1833
 Drosophila ingrica Hackman, 1957
 Drosophila innubila Spencer, 1943
 Drosophila inopinata Lachaise & Chassagnard, 2002
 Drosophila insignata Hardy, 1965
 Drosophila insignita Hardy, 1965
 Drosophila insularis Dobzhansky, 1957
 Drosophila intermedia Hardy, 1965
 Drosophila involuta Hardy, 1965
 Drosophila iroko Burla, 1954
 Drosophila ironensis Bock & Parsons, 1978
 Drosophila ischnotrix Hardy, 1965
 Drosophila itacorubi Doge, Gottschalk & Valente, 2011
 Drosophila ivai Vilela, 1983
 Drosophila jagri Prakash & Reddy, 1979
 Drosophila jambiya Grimaldi & Jones, 2020
 Drosophila jambulina Parshad & Paika, 1965
 Drosophila jesonica Matsumura, 1931
 Drosophila johnstonae Pipkin & Heed, 1964
 Drosophila joycei Hardy, 1965
印度果蝇 Drosophila (Sophophora) jumbilina Parshad & Paika, 1964
 Drosophila kahania Magnacca & O'Grady, 2008
 Drosophila kallima Wheeler, 1957
 Drosophila kambysellisi Hardy & Kaneshiro, 1969
 Drosophila kanaka Tsacas, 1988
 Drosophila kanapiae Bock & Wheeler, 1972
 Drosophila kanekoi Watabe & Higuchi, 1979
 Drosophila kaneshiroi Hardy, 1977
 Drosophila (Drosophila) karakasa Watabe & Liangg
 Drosophila kashmirensis Kumar & Gupta, 1985
 Drosophila kauaiensis Magnacca & O'Grady, 2008
 Drosophila kauluai Bryan, 1934
 Drosophila kepulauana Wheeler, 1969
 Drosophila kerteszina Duda, 1925
 Drosophila khansuensis Singh & Dash, 1994
 Drosophila khaoyana Bock & Wheeler, 1972
 Drosophila kikalaeleele Lapoint, Magnacca & O'Grady, 2009
 Drosophila kikiko Magnacca, 2012
吉川氏果蝇 Drosophila kikkawai Burla, 1954
 Drosophila kilimanjarica Lachaise & Chassagnard, 2001
 Drosophila kinabaluana Takada, Momma & Shima, 1973
 Drosophila kinoole Magnacca, 2012
 Drosophila kitagawai Toda, 1986
 Drosophila kitumensis Tsacas, 1985
 Drosophila kivuensis Tsacas, 1980
 Drosophila koepferae Fontdevila & Wasserman, 1988
 Drosophila kohkoa Wheeler, 1969
 Drosophila kokeensis Hardy, 1967
 Drosophila komohana Magnacca & O'Grady, 2009
 Drosophila konaensis Magnacca & O'Grady, 2008
 Drosophila krassi Hardy, 1965
 Drosophila kraussi Hardy, 1965
 Drosophila krimbasi Tsacas, 1985
 Drosophila krugi Pavan & Breuer, 1954
 Drosophila kualapa Magnacca & O'Grady, 2008
 Drosophila kualii Magnacca & O'Grady, 2009
 Drosophila kuhao Magnacca & O'Grady, 2008
 Drosophila kulango Burla, 1954
 Drosophila kulouriensis Fartyal & Singh, 2008
 Drosophila kuntzei Duda, 1924
 Drosophila kuoni Burla, 1954
 Drosophila kurillakta Penafiel-Vinueza & Rafael, 2019
 Drosophila kurseongensis Gupta & Singh, 1978
 Drosophila kweichowensis Tan, Hsu & Sheng, 1949
锯阳果蝇 Drosophila lacertosa Okada, 1956
 Drosophila lachaisei Tsacas, 1984
 Drosophila lacicola Patterson, 1944
 Drosophila laciniosa Hardy, 1965
 Drosophila lacteicornis Okada, 1965
 Drosophila lamellitarsis Duda, 1936
 Drosophila lamottei Tsacas, 1980
 Drosophila lanaiensis Grimshaw, 1901
 Drosophila larifuga Hardy, 1965
 Drosophila lasiopoda Hardy & Kaneshiro, 1975
 Drosophila latebuccata Duda, 1927
 Drosophila latecarinata Duda, 1927
 Drosophila (Drosophila) latifrons Adams, 1905
 Drosophila latigena Hardy, 1965
 Drosophila latipaenula Okada & Carson, 1982
 Drosophila lauoho Magnacca & O'Grady, 2008
 Drosophila lauta Wheeler & Takada, 1962
 Drosophila lebanonensis Wheeler
 Drosophila lelolua Magnacca & O'Grady, 2009
 Drosophila lemniscata Hardy, 1965
 Drosophila leoni Pipkin, 1964
 Drosophila leonis Patterson & Wheeler, 1942
 Drosophila leontia Tsacas & David, 1978
 Drosophila lepidobregma Hardy, 1965)
 Drosophila leticiae Pipkin, 1967
 Drosophila leukorrhyna Pipkin, 1964
 Drosophila levii Tsacas, 1988
 Drosophila liae Toda & Peng, 1989
 Drosophila libellulosa Tsacas & Legrand, 1979
 Drosophila lichuanensis Zhang & Liang, 1994
 Drosophila limbata Roser, 1840
 Drosophila limbinervis Duda, 1925
 Drosophila limbiventris Duda, 1925
 Drosophila limensis Pavan & Patterson, 1947
 Drosophila limingi Gao & Watabe, 2003
 Drosophila limitata Hardy & Kaneshiro, 1968
 Drosophila limpiensis Mainland, 1941
 Drosophila lindae Wheeler, 1968
 Drosophila linearepleta Patterson & Wheeler, 1942
 Drosophila linearidentata Toda, 1986
 Drosophila linearis Walker, 1853
 Drosophila lineata Wulp, 1881
小条纹果蝇 Drosophila lineolata Meijere, 1914
白纹果蝇 Drosophila (Drosophila) lineosa (Walker, 1859)
 Drosophila lineosetae Hardy & Kaneshiro, 1968
林氏果蝇 Drosophila lini Bock & Wheeler, 1972
 Drosophila liophallus Hardy & Kaneshiro, 1968
 Drosophila lissodora Hardy & Kaneshiro, 2001
 Drosophila (Drosophila) litorella Meigen, 1838)
 Drosophila littoralis Meigen, 1830
 Drosophila liui Chen, 1988
蓝脉果蝇 Drosophila (Drosophila) lividinervis Duda, 1923
 Drosophila lobatopalpus Kam & Perreira, 2003
 Drosophila loewi Vilela & Bachli, 2000
 Drosophila loiciana Tsacas & Chassagnard, 2000
 Drosophila longecrinita Duda, 1924
长角果蝇 Drosophila longicornis Patterson & Wheeler, 1942
 Drosophila longicrinis Lachaise & Chassagnard, 2002
长额果蝇 Drosophila (Drosophila) longifrons Duda, 1923
 Drosophila longipalpus Magnacca & O'Grady, 2008
 Drosophila longipectinata Takada, Momma & Shima, 1973
 Drosophila longiperda Kambysellis, 1993
 Drosophila longiperdis Kambysellis, 1993
 Drosophila longiserrata Toda, 1988
 Drosophila longiseta Grimshaw, 1901
 Drosophila longisetae Zhang, 1991
 Drosophila longissima Okada & Carson, 1983
 Drosophila longitarsis Duda, 1931
 Drosophila longum Lin & Wheeler, 1977
 Drosophila lowei Heed, Crumpacker & Ehrman, 1968
透明翅果蝇 Drosophila (Sophophora) lucipennis Linnaeus, 1972
 Drosophila lugubripennis Duda, 1927
 Drosophila luguensis Gao & Toda, 2003
 Drosophila luisserrai Vilela & Bachli, 2002
 Drosophila lumiformis Hoenigsberg & Lin, 1977
 Drosophila lummei Hackman, 1972
 Drosophila lusaltans Magalhaes, 1962
 Drosophila (Drosophila) lutea Wiedemann, 1830)
 Drosophila luteola Hardy, 1965
 Drosophila (Sophophora) lutescens Okada, 1974
 Drosophila lutzii Sturtevant, 1916
 Drosophila machachensis Vela & Rafael, 2001
 Drosophila machalilla 
 Drosophila macquarti Wheeler, 1981
 Drosophila macrochaetae Hardy, 1965
 Drosophila macropolia Patterson & Mainland, 1944
 Drosophila macroptera Patterson & Wheeler, 1942
 Drosophila macrospina Stalker & Spencer, 1939
 Drosophila macrothrix Hardy & Kaneshiro, 1968
 Drosophila maculifrons Duda, 1927
 Drosophila maculinotata Okada, 1956
 Drosophila madeirensis Monclus, 1984
 Drosophila madikerii Muniyappa & Gupta, 1980
 Drosophila maemae Kam & Perreira, 2003
 Drosophila (Sophophora) magalhaesi Mourao & Bicudo, 1967
 Drosophila maggulae Gupta & Sundaran, 1990
 Drosophila magnabadia Patterson & Mainland, 1943
 Drosophila magnaquinaria Wheeler, 1954
 Drosophila magnimacula Hardy, 1965
 Drosophila magnipalpa Hardy, 1965
 Drosophila magnipecten Lin & Wheeler, 1977
 Drosophila magnipectinata Okada, 1956
 Drosophila mahican Sturtevant & Dobzhansky, 1936
 Drosophila mahui Magnacca & O'Grady, 2008
 Drosophila mainlandi Patterson, 1943
 Drosophila majtoi Ruiz-Fiegalan, 2003
 Drosophila makawao Magnacca & O'Grady, 2008
 Drosophila malagassya Tsacas & Rafael, 1982
 Drosophila malagasy Grimaldi & Jones, 2020
 Drosophila malayana Takada, 1976)
 Drosophila malele Magnacca & O'Grady, 2008
马勒哥果蝇 Drosophila (Sophophora) malerkotliana Parshad & Paika, 1965
 Drosophila mambilla Tsacas, 1980
 Drosophila mandibulata Magnacca & O'Grady, 2009
 Drosophila mangabeirai Malogolowkin, 1951
 Drosophila mapiriensis Vilela & Bachli, 1990
 Drosophila maracaya Wheeler, 1957
 Drosophila margarita Hunter, 1979
 Drosophila mariaehelenae Vilela, 1984
 Drosophila mariettae Vilela, 1983
 Drosophila martensis Wasserman & Wilson, 1957
 Drosophila maryensis Gupta & Dwivedi, 1980
 Drosophila matae Tsacas, 1980
 Drosophila mathisi Grimaldi & Nguyen, 1999
 Drosophila mathisi Vilela, 1983
 Drosophila matileana Tsacas, 2002
 Drosophila matilei Tsacas, 1975
 Drosophila mauritiana Tsacas & David, 1974
 Drosophila mawaena Magnacca & O'Grady, 2008
 Drosophila maya Heed & O'Grady, 2000
 Drosophila mayaguana Vilela, 1983
 Drosophila mayri Mather & Dobzhansky, 1962
 Drosophila mcclintockae Pipkin, 1964
 Drosophila mecocnemia Hardy, 1965
 Drosophila (Drosophila) medialis Hardy, 1965
 Drosophila mediana Hardy, 1965
 Drosophila mediobandes Dwivedi & Gupta, 1980
 Drosophila medioconstricta Watabe, Zhang & Gan, 1990
 Drosophila mediocris Frota-Pessoa, 1954
 Drosophila mediodelta Heed & Wheeler, 1957
 Drosophila mediodiffusa Heed & Wheeler, 1957
 Drosophila medioimpressa Frota-Pessoa, 1954
 Drosophila medioobscurata Duda, 1925
 Drosophila medioparva Heed & Wheeler, 1957
 Drosophila mediopicta Frota-Pessoa, 1954
 Drosophila mediopictoides Heed & Wheeler, 1957
 Drosophila (Drosophila) mediopunctata Dobzhansky Pavan
 Drosophila mediostriata Duda, 1925
 Drosophila mediovittata Frota-Pessoa, 1954
 Drosophila megalagitans Wheeler & Magalhaes, 1962
 Drosophila megapyga Tsacas, 1981
 Drosophila megaspis Bezzi, 1908
 Drosophila megasticta Hardy, 1965
 Drosophila meigeni Duda, 1935
 Drosophila meitanensis Tan, Hsu & Sheng, 1949
 Drosophila melanica Sturtevant, 1916
 Drosophila melanissima Sturtevant, 1916
 Drosophila (Drosophila) melanocephala Hardy, 1967)
黑腹果蝇 Drosophila (Drosophila) melanogaster Linnaeus, 1758
黑腹果蝇 Drosophila melanogaster Meigen, 1830
 Drosophila melanoloma Hardy, 1965
 Drosophila melanopedis Hardy, 1965
 Drosophila melanoptera Duda, 1927
 Drosophila melanosoma Grimshaw, 1901
 Drosophila melanura Miller, 1944
 Drosophila melina Wheeler, 1963
 Drosophila mellea Becker, 1919
 Drosophila mercatorum Patterson & Wheeler, 1942
 Drosophila meridiana Patterson & Wheeler, 1942
 Drosophila meridionalis Wasserman, 1962
 Drosophila merina Tsacas, 1997
 Drosophila merzi Vilela & Bachli, 2002
 Drosophila mesophragmatica Duda, 1927
 Drosophila mesostigma Frota-Pessoa, 1954
 Drosophila metasetigerata Gupta & Kumar, 1986
 Drosophila mettleri Heed, 1977
 Drosophila metzii Sturtevant, 1921
墨西哥果蝇 Drosophila mexicana Macquart, 1844
 Drosophila microdenticulata Panigrahy & Gupta, 1983
 Drosophila microlabis Seguy, 1938
 Drosophila micromelanica Patterson, 1941
 Drosophila micromettleri Heed, 1989
 Drosophila micromyia Hardy & Kaneshiro, 1975
 Drosophila micropectinata Takada & Momma, 1975
 Drosophila microralis Tsacas, 1981
 Drosophila milleri Magalhaes, 1962
 Drosophila milolii Magnacca & O'Grady, 2008
 Drosophila mimetica Bock & Wheeler, 1972
 Drosophila mimica Hardy, 1965
 Drosophila mimiconformis Hardy, 1965
 Drosophila mimiconfutata Hardy, 1965
 Drosophila minangkabau Zhang & Toda, 1995
 Drosophila minuta Walker, 1853
 Drosophila miranda Dobzhansky, 1935
 Drosophila misi Penafiel-Vinueza & Rafael, 2018
 Drosophila mitchelli Hardy, 1965
 Drosophila mitis Curran, 1936
 Drosophila mojavensis Patterson, 1940
 Drosophila moju Pavan, 1950
 Drosophila mojuoides Wasserman, 1962
 Drosophila moli Magnacca, 2012
 Drosophila molokaiensis Grimshaw, 1901
 Drosophila monieri McEvey & Tsacas, 1987
 Drosophila monochaeta Sturtevant, 1927
单色果蝇 Drosophila monocolor Wheeler, 1981
 Drosophila montana Patterson & Wheeler
 Drosophila montevidensis Goni & Vilela, 2016
 Drosophila montgomeryi Hardy & Kaneshiro, 1971
 Drosophila montium Meijere, 1916
 Drosophila morelia Vilela & Bachli, 2004
 Drosophila (Drosophila) morena Forta-Pessoa
 Drosophila moriwakii Okada & Kurokawa, 1957
 Drosophila mucunae Okada & Carson, 1982
 Drosophila mukteshwarensis Joshi, Fartyal & Singh, 2005
 Drosophila mulleri Sturtevant, 1921
 Drosophila mulli Perreira & Kaneshiro, 1991
 Drosophila multiciliata Hardy & Kaneshiro, 2001
 Drosophila multidentata Watabe & Zhang, 1990
 Drosophila multispina Okada, 1956
复纵纹果蝇 Drosophila (Drosophila) multistriata Duda, 1923
 Drosophila munda Spencer, 1942
 Drosophila mundagensis Sajjan & Reddy
 Drosophila murphyi Hardy & Kaneshiro, 1969
 Drosophila musae Hardy, 1965
 Drosophila musaphilia Hardy, 1965
 Drosophila mutica Toda, 1988
 Drosophila myamaungi Toda, 1991
 Drosophila mycethophila Goureau, 1865
 Drosophila mycetophila Hardy, 1965
 Drosophila mylenae David & Yassin, 2019
 Drosophila mysorensis Reddy & Krishnamurthy, 1970
 Drosophila nagarholensis Prakash & Reddy, 1980
 Drosophila nainitalensis Singh & Bhatt, 1988
 Drosophila nakanoi Zhang & Toda, 1995
 Drosophila nalomano Magnacca & O'Grady, 2009
 Drosophila nanella Hardy, 1965
 Drosophila nannoptera Wheeler, 1949
 Drosophila napoensis Guillin & Rafael, 2015
 Drosophila nappae Vilela, Valente & Basso-da-Silva, 2004
 Drosophila narragansett Sturtevant & Dobzhansky, 1936
 Drosophila nasuta Lamb, 1914
 Drosophila nasutoides Okada, 1964
 Drosophila natasha Gornostaev, 1992
 Drosophila navojoa Coyne, Eanes, Ramshaw & Koehn, 1979
 Drosophila navojoa Ruiz, Heed & Wasserman, 1990
 Drosophila nebulosa Sturtevant, 1916
 Drosophila neglecta Hardy, 1965
 Drosophila neoalagitans Wheeler & Magalhaes, 1962
 Drosophila neoamaguana Ramos-Guillin & Rafael, 2017
 Drosophila neobaimaii Singh & Dash, 1994
新巴氏果蝇 Drosophila neobusckii Toda, 1986
 Drosophila neocardini Streisinger, 1946
 Drosophila neochracea Wheeler, 1959
 Drosophila neoclavisetae Perreira & Kaneshiro, 1991
 Drosophila neocordata Magalhaes, 1956
新牵牛花果蝇 Drosophila neoelegans Gupta & Singh, 1978
 Drosophila neoelliptica Pavan & Magalhaes, 1950
 Drosophila neogata Lachaise & Chassagnard, 2001
 Drosophila neogrimshawi Hardy & Kaneshiro, 1968
 Drosophila neoguaramunu Frydenberg, 1956
 Drosophila neohaoyama Singh & Dash, 1994
 Drosophila neohexastriata Lin & Wheeler, 1977
新海德氏果蝇 Drosophila neohydei Wasserman, 1962
新雄黑果蝇 Drosophila neohypocausta Lin & Wheeler, 1973
新伊米果蝇 Drosophila neoimmigrans Gai & Krishnamurthy, 1982
 Drosophila neokadai Kaneko & Takada, 1966
 Drosophila neokhaoyana Singh & Dash, 1998
 Drosophila neokuntzei Singh & Gupta, 1981
 Drosophila neolacteicornis Hegde & Krishna, 1999
 Drosophila neomitra Chassagnard & Tsacas, 1997
 Drosophila (Drosophila) neomorpha Heed & Wheelr
 Drosophila neonasuta Sajjan & Krishnamurthy, 1972
 Drosophila neoperkinsi Hardy & Kaneshiro, 1968
 Drosophila neopicta Hardy & Kaneshiro, 1968
 Drosophila neoprosaltans Ramos-Guillin & Rafael, 2017
 Drosophila neorepleta Patterson & Wheeler, 1942
 Drosophila neosaltans Pavan & Magalhaes, 1950
 Drosophila neosignata Kumar & Gupta, 1988
 Drosophila neotestacea Grimaldi, James & Jaenike, 1992
新梯额果蝇 Drosophila neotrapezifrons Ranganath, Krishnamurthy & Hedge, 1983
 Drosophila neotruncata Sreerama Reddy & Krishnamurthy, 1972
 Drosophila neoyanayuyu Ramos-Guillin & Rafael, 2017
尼泊尔果蝇 Drosophila nepalensis Okada, 1955
 Drosophila nesiota Wheeler & Takada, 1962
 Drosophila nesoetes Bock & Wheeler, 1972
 Drosophila neutralis Hardy, 1965
 Drosophila ngemba Tsacas, 1980
 Drosophila nigella Hardy, 1965
 Drosophila nigra Grimshaw, 1901
 Drosophila nigrasplendens Pipkin, 1964
 Drosophila nigrialata Takada, Momma & Shima, 1973
 Drosophila nigriasis Lin & Wheeler, 1977
 Drosophila nigribasis Hardy, 1965
 Drosophila nigriceps Meigen, 1838
 Drosophila nigricincta Frota-Pessoa, 1954
 Drosophila nigricolor Strobl
 Drosophila nigricruria Patterson & Mainland, 1943
 Drosophila nigriculter Okada, 1988
 Drosophila nigridentata Watabe, Toda & Peng, 1995
 Drosophila nigrifemur Duda, 1927
 Drosophila nigrilineata Angus, 1967
 Drosophila nigripalpus Hardy, 1965
 Drosophila nigritarsus Hardy, 1965
 Drosophila nigrocirrus Hardy, 1965
黑趾果蝇 Drosophila (Drosophila) nigrodigita Lin & Ting, 1971)
 Drosophila nigrodumosa Wasserman & Fontdevila, 1990
 Drosophila nigrodunni Heed & Wheeler, 1957
 Drosophila nigrohydei Patterson & Wheeler, 1942
 Drosophila nigromaculata Kikkawa & Peng, 1938
 Drosophila nigromelanica Patterson & Wheeler, 1942
 Drosophila nigropleuralis Takada, Momma & Shima, 1973
 Drosophila nigropolita Hardy, 1965
 Drosophila nigrosaltans Magalhaes, 1962
 Drosophila nigrosparsa Strobl, 1898
 Drosophila nigrospinipes Grimaldi & Jones, 2020
 Drosophila nigrospiracula Patterson & Wheeler, 1942
 Drosophila nigrosubtilis Lin & Wheeler, 1977
黑小板果蝇 Drosophila nigrovesca Lin & Ting, 1971
 Drosophila nikananu Burla, 1954
 Drosophila nitida Tsacas & Chassagnard, 1994
 Drosophila nitidapex Bigot, 1891
 Drosophila niveifrons Okada & Carson, 1982
 Drosophila niveopunctata Dufour, 1846
 Drosophila nixifrons Tan, Hsu & Sheng, 1949
 Drosophila nodosa Duda, 1926
 Drosophila notostriata Okada, 1966
 Drosophila novamexicana Patterson, 1941
 Drosophila novaspinofera Gupta & Singh, 1979
 Drosophila novazonata Gupta & Dwivedi, 1980
 Drosophila novemaristata Dobzhansky & Pavan, 1943
 Drosophila novitskii Sulerud & Miller, 1966
 Drosophila novocalloptera Pavan, 1952
 Drosophila novodaruma Lin & Wheeler, 1977
 Drosophila novohistrio Lin & Wheeler, 1977
 Drosophila novolacertosa Lin & Wheeler, 1977
 Drosophila nubeculatipennis Zhang, Chen, Peng & Lin, 1996
 Drosophila nubiluna Wheeler, 1949
 Drosophila nukea Magnacca, 2012
 Drosophila nullilineata Zhang & Toda, 1988
 Drosophila nutrita Duda, 1935
 Drosophila nyinyii Toda, 1991
 Drosophila (Drosophila) oahuensis Grimshaw, 1901)
 Drosophila obatai Hardy & Kaneshiro, 1972
 Drosophila obscura Fallen, 1823
小灰果蝇 Drosophila obscurata Meijere, 1911
 Drosophila obscuricolor Duda, 1927
 Drosophila obscuricornis Meijere
 Drosophila obscurinervis Toda, 1986
 Drosophila (Drosophila) obscuripes Grimshaw, 1901)
 Drosophila ocampoae Ruiz-Fiegalan, 2003
 Drosophila occidentalis Spencer, 1942
 Drosophila ocellata Hardy & Kaneshiro, 1969
 Drosophila ochracea Grimshaw, 1901
 Drosophila (Drosophila) ochrifrons Duda, 1924
 Drosophila ochrobasis Hardy & Kaneshiro, 1968
 Drosophila ochrogaster Chassagnard, 1992
 Drosophila ochropleura Hardy & Kaneshiro, 2001
 Drosophila odontophallus Hardy & Kaneshiro, 1968
 Drosophila odontostoma Kam & Perreira, 2003
 Drosophila (Drosophila) oenopota Scopoli, 1763)
 Drosophila ogumai Zannat & Toda, 2002
 Drosophila ohiensis Spencer, 1940
 Drosophila ohioensis Spencer, 1940
 Drosophila ohnishii Zannat & Toda, 2002
 Drosophila okadai Takada, 1959
 Drosophila okala Magnacca & O'Grady, 2008
 Drosophila olaae Grimshaw, 1901
 Drosophila omnivora Magnacca & O'Grady, 2009
 Drosophila (Drosophila) onca Dobzhanksy & Pavan
 Drosophila onychophora Duda, 1927
 Drosophila ophthalmitis Tsacas, 2006
 Drosophila opuhe Magnacca, 2012
 Drosophila orascopa Magnacca & O'Grady, 2009
 Drosophila oreas Hardy, 1965
 Drosophila oreia Tsacas, 1980
 Drosophila orena Tsacas & David, 1978
 Drosophila orestes Hardy, 1965
 Drosophila oribatis Tsacas, 1980
 Drosophila orientacea Grimaldi, James & Jaenike, 1992
 Drosophila oritisa Chen, 1990
 Drosophila orkui Brncic & Koref-Santibanez, 1957
 Drosophila ornata Hardy & Kaneshiro, 1969
 Drosophila ornatifrons Duda, 1927
 Drosophila ornatipennis Williston, 1896
 Drosophila orosa Bock & Wheeler, 1972
 Drosophila orphnaea Tsacas, 2001
 Drosophila orphnopeza Hardy & Kaneshiro, 1968
 Drosophila orthofascia Hardy & Kaneshiro, 1968
 Drosophila orthophallata Katoh & Gao, 2018
 Drosophila orthoptera Hardy, 1965)
 Drosophila oshimai Choo & Nakamura, 1973
 Drosophila othoni Pipkin, 1964
 Drosophila pachea Patterson & Wheeler, 1942
 Drosophila pachneissa Tsacas, 2002
 Drosophila pachuca Wasserman, 1962
太平果蝇 Drosophila pacificae Matsuda, 2005
 Drosophila padangensis Zhang & Toda, 1995
 Drosophila paenehamifera Hardy & Kaneshiro, 1969
 Drosophila pagliolii Cordeiro, 1963
 Drosophila pagoda Toda, 1988
 Drosophila paharpaniensis Singh & Dash, 1994
 Drosophila painii Singh & Negi, 1992
 Drosophila pallidifrons Wheeler, 1969
 Drosophila pallidipennis Dobzhansky & Pavan, 1943
 Drosophila pallidosa Bock & Wheeler, 1972
 Drosophila (Drosophila) pallipes Dufour, 1846
 Drosophila palmata Takada, Momma & Shima, 1973
 Drosophila palniensis Hegde & Shakunthala, 1999
 Drosophila palustris Dahl, 1896
 Drosophila palustris Spencer, 1942
 Drosophila panamensis Malloch, 1926
 Drosophila pandora McEvey & Schiffer, 2015
 Drosophila panina Magnacca & O'Grady, 2008
 Drosophila panoanoa Magnacca & O'Grady, 2008
 Drosophila papaalai Magnacca & O'Grady, 2008
 Drosophila papala Magnacca & O'Grady, 2008
 Drosophila papei Bachli & Vilela, 2002
 Drosophila papilla Zhang & Shi, 1992
拟双梳果蝇 Drosophila parabipectinata Bock, 1971
 Drosophila (Sophophora) parabocainensis Carson, 1954
 Drosophila paracalloptera Pavan, 1952
 Drosophila paracanalinea Wheeler, 1957
 Drosophila parachrogaster Patterson & Mainland, 1943
 Drosophila paracracens Hardy & Kaneshiro, 1979
 Drosophila paragata Lachaise & Chassagnard, 2001
 Drosophila paraguayensis Duda, 1927
 Drosophila paraguttata Thompson, 1957
 Drosophila paraimmigrans Gai & Krishnamurthy, 1986
 Drosophila paraitacorubi Doge, Gottschalk & Valente, 2011
 Drosophila parakuntzei Okada, 1973
 Drosophila paralatinokogiri Okada, 1991
 Drosophila paralutea Bock & Wheeler, 1972
 Drosophila paramarginata Singh & Dash, 1994
 Drosophila paramediostriata Townsend & Wheeler, 1955
 Drosophila paramelanica Griffen, 1942
 Drosophila paranaensis Barros, 1950
 Drosophila parannularis Vilela & Bachli, 1990
 Drosophila paranthrax Hardy & Kaneshiro, 2001
 Drosophila parapallidosa Tobari, 2009
 Drosophila parasaltans Magalhaes, 1956
 Drosophila parasignata Takada, Momma & Shima, 1973
 Drosophila paratarsata Vilela, 1985
 Drosophila paraviaristata Takada, Momma & Shima, 1973
拟髭果蝇 Drosophila (Drosophila) paravibrissina Duda, 1924
 Drosophila parazonata Gupta & Dwivedi, 1980
 Drosophila parisiena Heed
 Drosophila parthenogenetica Stalker, 1953
 Drosophila parviprocessata Toda, 1986
 Drosophila parvula Bock & Wheeler, 1972
 Drosophila pasochoensis Vela & Rafael, 2001
 Drosophila paucicilia Hardy & Kaneshiro, 1971
 Drosophila paucilineata Burla, 1957
 Drosophila paucipuncta Grimshaw, 1901
 Drosophila paucitarsus Hardy & Kaneshiro, 1979
 Drosophila paucula Hardy, 1965
 Drosophila pauliceia Ratcov & Vilela, 2007
 Drosophila paulistorum Dobzhansky & Pavan, 1949
 Drosophila (Drosophila) paunii Singh & Negi, 1989
 Drosophila pavani Brncic, 1957
 Drosophila pavlovskiana Kastritsis & Dobzhansky, 1967
 Drosophila pectinifera Wheeler & Takada, 1964
 Drosophila pectinitarsus Hardy, 1965
 Drosophila pedroi Vilela, 1984
 Drosophila pegasa Wasserman, 1962
 Drosophila pellewae Pipkin & Heed, 1964
 Drosophila peloristoma Magnacca & O'Grady, 2009
 Drosophila penicillipennis Takada, Momma & Shima, 1973
毛刷果蝇 Drosophila (Lordiphosa) penicula Okada, 1984
 Drosophila peniculipedis Hardy, 1965
 Drosophila penidentata Singh & Gupta, 1981
 Drosophila peninsularis Patterson & Wheeler, 1942
 Drosophila penispina Gupta & Singh, 1979
 Drosophila pennae Bock & Wheeler, 1972
 Drosophila penniclubata Singh & Gupta, 1981
 Drosophila pentafuscata Gupta & Kumar, 1986
 Drosophila pentaspina Parshad & Duggal, 1967
 Drosophila pentastriata Okada, 1966
 Drosophila percnosoma Hardy, 1965
 Drosophila pereirai Takada, Momma & Shima, 1973
 Drosophila periquito Bachli & Vilela, 2002
 Drosophila perissopoda Hardy, 1965
 Drosophila perlucida Zhang & Liang, 1994
 Drosophila perrisi Wheeler & Hamilton, 1972
 Drosophila persicae Bock & Parsons, 1978
 Drosophila persimilis Dobzhansky & Epling, 1944
 Drosophila peruensis Wheeler, 1959
 Drosophila peruviana Duda, 1927
 Drosophila petalopeza Hardy, 1965
 Drosophila petitae Tsacas, 1981
 Drosophila phaeopleura Bock & Wheeler, 1972
 Drosophila phalerata Meigen, 1830
 Drosophila phalloserra Grimaldi & Jones, 2020
 Drosophila phyale Tsacas, 1981
 Drosophila (Idiomyia) picea Hardy, 1977
 Drosophila pichinchana Vela & Rafael, 2003
 Drosophila picta Zetterstedt, 1847
 Drosophila picticornis Grimshaw, 1901
 Drosophila pictifrons Duda, 1927
 Drosophila pictilis Wasserman, 1962
 Drosophila pictura Grimaldi, 1987
 Drosophila pictura Wasserman, 1962
 Drosophila pihulu Magnacca, 2012
 Drosophila pilacrinis Lachaise & Chassagnard, 2002
 Drosophila pilaresae Vela & Rafael, 2001
 Drosophila pilatisetae Hardy & Kaneshiro, 1968
 Drosophila pilimana Grimshaw, 1901
 Drosophila pilipa Magnacca, 2012
 Drosophila pilocornuta Lachaise & Chassagnard, 2001
 Drosophila pilosa Watabe & Peng, 1991
 Drosophila pinicola Sturtevant, 1942
 Drosophila pinnitarsus Bock, 1976
 Drosophila pisonia Hardy & Kaneshiro, 1971
 Drosophila pittieri Bachli & Vilela, 2002
 Drosophila plagiata Bezzi, 1908
 Drosophila planitibia Hardy, 1967)
 Drosophila platitarsus Frota-Pessoa, 1954
 Drosophila plumosa Grimshaw, 1901
 Drosophila poecilogastra Duda, 1926
 Drosophila pohaka Magnacca & O'Grady, 2008
 Drosophila (Drosophila) poinari Grimaldi, 1987
 Drosophila polita Grimshaw, 1901
 Drosophila polliciforma Hardy, 1965
 Drosophila pollinospadix Patterson & Mainland, 1944
 Drosophila polychaeta Patterson & Wheeler, 1942
 Drosophila polymorpha Dobzhansky & Pavan, 1943
 Drosophila ponderosa Patterson & Mainland, 1943
 Drosophila ponera Tsacas & David, 1975
 Drosophila poonia Magnacca & O'Grady, 2008
 Drosophila popayan Vilela & Bachli, 2004
 Drosophila populi Wheeler & Throckmorton, 1961
长身果蝇 Drosophila (Lordiphosa) porrecta Okada, 1984
 Drosophila potamogigas Zhang, Chen, Peng & Lin, 1996
 Drosophila potamophila Toda & Peng, 1989
 Drosophila praesutilis Hardy, 1965
 Drosophila prashadi Brunetti, 1923
 Drosophila preapicula Hardy, 1965)
 Drosophila pretiosa Hardy, 1965
 Drosophila primaeva Hardy & Kaneshiro, 1968
 Drosophila procardinoides Frydenberg, 1956
 Drosophila proceriseta Hardy, 1965
 Drosophila prodispar Duda, 1927
 Drosophila prodispar Parsons & Bock, 1982
 Drosophila prodita Hardy, 1965
 Drosophila progastor Bock, 1976
 Drosophila prolaticilia Hardy, 1965
 Drosophila prolixa Hardy, 1965
 Drosophila prolongata Singh & Gupta, 1977
 Drosophila promeridiana Wasserman, 1962
 Drosophila prominens Hardy, 1965
 Drosophila propachuca Wasserman, 1962
 Drosophila propiofacies Hardy, 1965
 Drosophila prorepleta Duda, 1925
 Drosophila prosaltans Duda, 1927
 Drosophila prosimilis Duda, 1927
黑端翅果蝇 Drosophila (Sophophora) prostipennis Linnaeus, 1972
 Drosophila prostopalpis Hardy & Kaneshiro, 1968
 Drosophila pruinifacies Frota-Pessoa, 1954
 Drosophila pruinosa Duda, 1940
假嗜凤梨果蝇 Drosophila pseudoananassae Bock, 1971
 Drosophila pseudoargentostriata Wheeler, 1981
 Drosophila pseudobaimaii Takada, Momma & Shima, 1973
 Drosophila pseudobocainensis Wheeler & Magalhaes, 1962
 Drosophila pseudodenticulata Takada & Momma, 1975
 Drosophila pseudokomaii Sheng, Tan & Chen, 1944
 Drosophila pseudokorefae Ramos-Guillin & Rafael, 2018
 Drosophila pseudomayri Baimai, 1970
 Drosophila pseudomorelia Ramos-Guillin & Rafael, 2018
 Drosophila pseudoobscura Frolova, 1929
 Drosophila pseudorepleta Vilela & Bachli, 1990
 Drosophila pseudosaltans Magalhaes, 1956
 Drosophila pseudosordidula Kaneko & Tokumitsu, 1964
假高桥氏果蝇 Drosophila pseudotakahashii Mather, 1957
 Drosophila pseudotalamancana Pereira & Vilela, 1987
 Drosophila pseudotetrachaeta Angus, 1967
 Drosophila psilophallus Hardy & Kaneshiro, 1971
 Drosophila psilotarsalis Hardy & Kaneshiro, 1975
 Drosophila pterocelis Tsacas & Chassagnard, 1999
 Drosophila puberula Katoh & Gao, 2018
 Drosophila pulaua Wheeler, 1969
 Drosophila pulchella Sturtevant, 1916
艳丽果蝇 Drosophila pulchrella Tan, Hsu & Sheng, 1949
 Drosophila pullata Tan, Hsu & Sheng, 1949
 Drosophila pullipes Hardy & Kaneshiro, 1972
 Drosophila pulverea Duda, 1927
 Drosophila punalau Bryan
 Drosophila punalua Bryan, 1934
 Drosophila (Drosophila) punctatipennis Tscas & David
 Drosophila punctatonervosa Frey, 1954
 Drosophila punjabiensis Parshad & Paika, 1965
 Drosophila purpurea Gupta & Sundaran, 1990
 Drosophila pusilla Eversmann, 1834
 Drosophila putrida Sturtevant, 1916
 Drosophila pychnochaetae Hardy, 1965
 Drosophila pyo Toda, 1991
 Drosophila qiongzhouensis Katoh & Gao, 2018
 Drosophila qionzhouensis Katoh & Gao, 2018
季白颜果蝇 Drosophila (Sophophora) quadraria Bock & Wheeler, 1972
四线果蝇 Drosophila quadrilineata Meijere, 1911
 Drosophila (Drosophila) quadriseriata Duda, 1924
 Drosophila quadriserrata Okada & Carson, 1982
 Drosophila quadrisetae Hardy, 1965
 Drosophila quadrisetata Takada, Beppu & Toda, 1979
 Drosophila quadrum Wiedemann, 1830)
 Drosophila quasianomalipes Hardy, 1965
 Drosophila quasiexpansa Hardy, 1965
 Drosophila quatrou Tsacas, 1980
 Drosophila querubimae Vilela, 1983
 Drosophila quijos Guillin & Rafael, 2015
 Drosophila quinarensis Penafiel-Vinueza & Rafael, 2018
 Drosophila quinaria Loew, 1866
 Drosophila quinqueannulata Frey, 1917
 Drosophila quinqueramosa Hardy & Kaneshiro, 2001
五条纹果蝇 Drosophila quinquestriata Lin & Wheeler, 1973
 Drosophila quitensis Vela & Rafael, 2003
 Drosophila racemova Patterson & Mainland, 1944
 Drosophila rafaeli Vela & Rafael
 Drosophila ramamensis Dwivedi, 1979
 Drosophila ramsdeni Sturtevant, 1916
 Drosophila ranchograndensis Bachli & Vilela, 2002
 Drosophila reaumurii Dufour, 1845
 Drosophila recens Wheeler, 1960
 Drosophila rectangularis Sturtevant, 1942
 Drosophila recticilia Hardy & Kaneshiro, 1968
 Drosophila redunca Hardy, 1965
 Drosophila rellima Wheeler, 1960
 Drosophila (Drosophila) repleta Duda
黑斑果蝇 Drosophila repleta Wollaston, 1858
 Drosophila repletoides Hsu, 1943
 Drosophila reschae Hardy & Kaneshiro, 1975
 Drosophila residua Hardy, 1965
 Drosophila reticulata Wheeler, 1957
 Drosophila retnasabapathyi Takada & Momma, 1975
 Drosophila retrusa Hardy, 1965
 Drosophila reynoldsiae Hardy & Kaneshiro, 1972
 Drosophila rhombura Okada & Carson, 1983
 Drosophila rhopaloa Bock & Wheeler, 1972
 Drosophila richardsoni Vilela, 1983
 Drosophila ritae Patterson & Wheeler, 1942
 Drosophila robusta Sturtevant, 1916
 Drosophila roehrae Pipkin & Heed, 1964
 Drosophila rosinae Vilela, 1983
 Drosophila rostrata Duda, 1925
 Drosophila ruberrima Meijere, 1911
 Drosophila ruberrimoides Zhang & Gan, 1986
 Drosophila rubida Mather, 1960
 Drosophila rubidifrons Patterson & Mainland, 1944
 Drosophila rubra Sturtevant, 1927
 Drosophila rubrifrons Patterson & Wheeler, 1942
暗褐大果蝇 Drosophila rubrrima Meijere, 1911
 Drosophila ruburra Hardy, 1965
 Drosophila rufa Kikkawa & Peng, 1938
 Drosophila ruizi Ruiz-Fiegalan, 2004
 Drosophila ruminahuii Vela & Rafael, 2004
 Drosophila rustica Hardy, 1965
 Drosophila sabroskyi Hardy, 1965
 Drosophila sachapuyu Penafiel-Vinueza & Rafael, 2018
 Drosophila sadleria Bryan, 1938
 Drosophila sadleria Hardy, 1965
 Drosophila sahyadrii Prakash & Reddy, 1979
 Drosophila salpina Chen, 1994
 Drosophila saltans Sturtevant, 1916
 Drosophila sampagensis Muniyappa & Reddy, 1980
 Drosophila sannio Gornostaev, 1991
 Drosophila santomea Lachaise & Harry, 2000
 Drosophila saraguru Penafiel-Vinueza & Rafael, 2019
 Drosophila saraswatii Singh & Dash, 1994
 Drosophila sargakhetensis Joshi, Fartyal & Singh, 2005
 Drosophila sattalensis Fartyal & Singh, 1994
 Drosophila scaptomyzoptera Duda, 1935
 Drosophila schachti Bachli, Vilela & Haring, 2002
 Drosophila schildi Malloch, 1924
 Drosophila schineri Pereira & Vilela, 1987
 Drosophila (Sophophora) schmidti Duda, 1924
 Drosophila schugi McEvey & Schiffer, 2015
 Drosophila scioptera Duda, 1927
 Drosophila scitula Hardy, 1967
 Drosophila scolostoma Hardy, 1965
 Drosophila scopata Bock, 1976
 Drosophila scuhgi McEvey & Schiffer, 2015
 Drosophila sechellia Tsacas & Bachli, 1981
 Drosophila seclusa Hardy, 1965
 Drosophila secunda Maca, 1992
 Drosophila seguyi Smart, 1945
 Drosophila seguyiana Chassagnard & Tsacas, 1997
 Drosophila sejuncta Hardy & Kaneshiro, 1968
 Drosophila semialba Duda, 1925
 Drosophila semiatra Meijere, 1914
 Drosophila semifuscata Hardy, 1965
 Drosophila seminole Sturtevant & Dobzhansky, 1936
 Drosophila semipruinosa Tsacas, 2002
 Drosophila senei Vilela, 1983
 Drosophila senilis Duda, 1926
 Drosophila senticosa Zhang & Toda, 1995
 Drosophila seorsa Hardy, 1965
 Drosophila septacoila Gai & Krishnamurthy, 1984
 Drosophila septentriosaltans Magalhaes & Buck, 1962
 Drosophila septuosa Hardy, 1965
 Drosophila serenensis Brncic, 1957
 Drosophila serido Vilela & Sene, 1977
 Drosophila seriema Tidon-Sklorz & Sene, 1995
 Drosophila serrata Malloch, 1927
 Drosophila serripaenula Okada & Carson, 1982
 Drosophila serrula Tsacas, 1984
 Drosophila serrulata Zhang & Toda, 1995
 Drosophila setapex Patterson & Mainland, 1944
 Drosophila (Sophophora) setifemur Malloch
 Drosophila (Drosophila) setiger Grimshaw, 1901
 Drosophila setipalpus Hardy, 1965
 Drosophila setipenis Zhang, Chen, Peng & Lin, 1996
 Drosophila setitarsa Gupta & Dwivedi, 1980
 Drosophila setosifrons Hardy & Kaneshiro, 1968
 Drosophila setosimentum Hardy & Kaneshiro, 1968
 Drosophila setositibia Hardy & Kaneshiro, 2001
 Drosophila setula Heed & Wheeler, 1957
 Drosophila sexlineata Duda, 1940
 Drosophila seyanii Chassagnard & Tsacas, 1997
 Drosophila sharpi Grimshaw, 1901
 Drosophila shiri Hoenigsberg, 1995
 Drosophila shwezayana Toda, 1986
 Drosophila shyri Vela & Rafael, 2004
 Drosophila siamana Ikeda, Hihara, Asada, Fujiwara & Lin, 1983
 Drosophila siangensis Kumar & Gupta, 1988
 Drosophila sierrae Ruiz-Fiegalan, 2003
 Drosophila sigmoides Loew, 1872
纹整果蝇 Drosophila (Drosophila) signata Duda, 1923)
 Drosophila silvarentis Hardy & Kaneshiro, 1968
银黄果蝇 Drosophila silvata Meijere, 1916
 Drosophila silvestris Perkins, 1910)
 Drosophila (Drosophila) similis Williston, 1896
拟果蠅 Drosophila simulans Sturtevant, 1919
 Drosophila simulivora Tsacas & Disney, 1974
分瓣果蝇 Drosophila singulata Duda, 1924
中华灰果蝇 Drosophila sinobscura Watabe, 1996
 Drosophila sinuata Bock, 1982
 Drosophila slossonae Johnson, 1913
 Drosophila smithersi Bock, 1976
 Drosophila sobrina Hardy & Kaneshiro, 1971
 Drosophila sodomae Hardy & Kaneshiro, 1968
 Drosophila sogo Burla, 1954
 Drosophila solennis Walker, 1860
 Drosophila solstitialis Chen, 1994
 Drosophila sonorae Heed & Castrezana, 2008
 Drosophila soonae Takada & Yoon, 1989
 Drosophila sordidapex Grimshaw, 1901
 Drosophila sordidula Kikkawa & Peng, 1938
 Drosophila soror Schiner, 1868
 Drosophila spadicifrons Patterson & Mainland, 1944
 Drosophila spaniothrix Hardy & Kaneshiro, 1968
 Drosophila speciosa Silva & Martins, 2004
 Drosophila spectabilis Grimshaw
 Drosophila spectabilis Hardy, 1965
 Drosophila spenceri Patterson, 1943
 Drosophila sphaerocera Thomson, 1869
 Drosophila spicula Hardy, 1965
 Drosophila spiethi Hardy, 1967
 Drosophila spinatermina Heed & Wheeler, 1957
 Drosophila spinula Okada & Carson, 1982
 Drosophila sproati Hardy & Kaneshiro, 1968
 Drosophila spuricurviceps Zhang & Gan, 1986
 Drosophila stalkeri Wheeler, 1954
 Drosophila starmeri Wasserman, Koepfer & Ward, 1973
 Drosophila statzi Ashburner & Bachli, 2004
 Drosophila stenoptera Hardy, 1965
 Drosophila stenotrichala Lachaise & Chassagnard, 2002
 Drosophila stephanosi Tsacas, 2003
 Drosophila sternopleuralis Okada & Kurokawa, 1957
 Drosophila sticta Wheeler, 1957
 Drosophila stictoptera Tsacas & Chassagnard, 1999
 Drosophila stigma Hardy, 1977
 Drosophila straubae Heed, 1991
 Drosophila striaticeps Wheeler & Takada, 1966
 Drosophila strigiventris Duda, 1927
 Drosophila sturtevanti Duda, 1927
四反里果蝇 Drosophila (Lordiphosa) subantillaria Okada, 1984
 Drosophila subaquatica Suwito & Watabe, 2010
亚白颜果蝇 Drosophila subauraria Kimura, 1983
 Drosophila subbadia Patterson & Mainland, 1943
亚牵牛花果蝇 Drosophila subelegans Okada, 1988
 Drosophila subfasciata Meijere, 1914
 Drosophila subfunebris Stalker & Spencer, 1939
 Drosophila subinfumata Duda, 1925
 Drosophila submacroptera Patterson & Mainland, 1943
 Drosophila subobscura Collin, 1936
 Drosophila suboccidentalis Spencer, 1942
 Drosophila subopaca Hardy & Kaneshiro, 2001
 Drosophila suborosa Kumar & Gupta, 1992
 Drosophila subpalustris Spencer, 1942
亚艳丽果蝇 Drosophila subpulchrella Takamori & Watabe, 2006
 Drosophila subsaltans Magalhaes, 1956
 Drosophila subsilvestris Hardy & Kaneshiro, 1968
 Drosophila (Drosophila) substenoptera Hardy, 1965
 Drosophila subviridis Patterson & Mainland, 1943
 Drosophila (Drosophila) succini Grimaldi, 1987
 Drosophila sucinea Patterson & Mainland, 1944
 Drosophila suffusca Spencer, 1943
苏氏果蝇 Drosophila sui Lin & Tseng, 1973
 Drosophila sulfurigaster Duda, 1923)
 Drosophila sungaicola Suwito & Watabe, 2010
 Drosophila surangensis Singh & Dash, 1994
 Drosophila suturalis Wheeler, 1957
铃木氏果蝇 Drosophila suzukii Matsumura, 1931)
 Drosophila swezeyi Hardy, 1965
 Drosophila sycophaga Tsacas, 1981
 Drosophila sycophila Tsacas, 1981
 Drosophila sycovora Tsacas, 1981
 Drosophila synpanishi Okada, 1964
 Drosophila systenopeza Hardy & Kaneshiro, 1979
 Drosophila taekjuni Kim & Joo, 2002
 Drosophila taeniata Hardy, 1965
 Drosophila taiensis Kumar & Gupta, 1988
太平山果蝇 Drosophila taipinsanensis Lin & Tseng, 1973
高桥氏果蝇 Drosophila takahashii Sturtevant, 1927
 Drosophila talamancana Wheeler, 1968
 Drosophila talasica Gornostaev, 1991
 Drosophila tamashiroi Hardy, 1965
 Drosophila tani Cheng & Okada, 1985
 Drosophila tanorum Okada, 1964
 Drosophila tanytarsis Hardy & Kaneshiro, 2001
 Drosophila tanythrix Hardy, 1965)
 Drosophila taractica Hardy, 1965
 Drosophila tarphytrichia Hardy, 1965
 Drosophila tarsalis Walker, 1853
 Drosophila tarsata Schiner, 1868
 Drosophila teissieri Tsacas, 1971
 Drosophila tenda Wheeler, 1959
 Drosophila tendomentum Hardy, 1965
 Drosophila tenebrosa Spencer, 1943
 Drosophila tenuipes Walker, 1849)
 Drosophila teratos Bock, 1982
 Drosophila testacea Roser, 1840
 Drosophila testacens Wheeler, 1981
 Drosophila tetrachaeta Angus, 1964
 Drosophila tetradentata Singh & Gupta, 1981
 Drosophila tetraspilota Hardy, 1965
 Drosophila tetravittata Takada & Momma, 1975
 Drosophila texana Patterson, 1940
 Drosophila thienemanni Duda, 1931
 Drosophila tibialis Wheeler, 1957
 Drosophila tibudu Burla, 1954
 Drosophila tinalandia Llangari Arizo & Rafael, 2018
 Drosophila tjibodas Meijere, 1916
 Drosophila tolteca Patterson & Mainland, 1944
 Drosophila tomasi Vela & Rafael, 2001
 Drosophila tongpua Lin & Tseng, 1973
东埔大果蝇 Drosophila tonpua Lin & Ting, 1971
 Drosophila torquata Zhang & Toda, 1995
 Drosophila torrei Sturtevant, 1921
 Drosophila torula Hardy, 1965
 Drosophila totonigra Hardy, 1965
 Drosophila touchardiae Hardy & Kaneshiro, 1972
 Drosophila toxacantha Magnacca & O'Grady, 2009
 Drosophila toxochaeta Perreira & Kaneshiro, 1991
丰日氏长果蝇 Drosophila toyohii Lin & Tseng, 1972
 Drosophila tranquilla Spencer, 1943
 Drosophila transversa Fallen, 1823
 Drosophila trapeza Heed & Wheeler, 1957
梯额果蝇 Drosophila trapezifrons Okada, 1966
 Drosophila triaina Lu & Zhang, 2004)
 Drosophila triangula Wheeler, 1949
 Drosophila triangulina Duda, 1927
 Drosophila triantilia Okada, 1988
 Drosophila triauraria Bock & Wheeler, 1972
 Drosophila trichaeta Angus, 1967
 Drosophila trichaetosa Hardy, 1965
 Drosophila trichala Lachaise & Chassagnard, 2002
 Drosophila trichiaspis Duda, 1940
 Drosophila tricombata Singh & Gupta, 1977
 Drosophila trifiloides Wheeler, 1957
 Drosophila trifilum Frota-Pessoa, 1954
 Drosophila trilimbata Bezzi, 1928
三暗黄果蝇 Drosophila trilutea Bock & Wheeler, 1972
 Drosophila tripunctata Loew, 1862
 Drosophila trisetosa Okada, 1966
 Drosophila trispina Wheeler, 1949
 Drosophila tristani Sturtevant, 1921
三戟翅果蝇 Drosophila (Sophophora) tristipennis Duda, 1923
 Drosophila (Drosophila) tristipes Duda, 1924
 Drosophila tristis Fallen, 1823
 Drosophila tristriata Heed & Wheeler, 1957
 Drosophila trivittata Eversmann, 1834
 Drosophila trizonata Okada, 1966
 Drosophila tropicalis Burla & Cunha, 1949
 Drosophila truncata Okada, 1964
 Drosophila truncipenna Hardy, 1965
 Drosophila tsacasi Bock & Wheeler, 1972
 Drosophila tschirnhausi Bachli & Vilela, 2002
 Drosophila tsigana Burla & Gloor, 1952
筑波果蝇 Drosophila tsukubaensis Takamori, 1983
 Drosophila tuchaua Pavan, 1950
土库曼果蝇 Drosophila tucumana Vilela & Pereira, 1985
 Drosophila tumensa Lin & Wheeler, 1977
 Drosophila turbata Hardy & Kaneshiro, 1969
 Drosophila tychaea Tsacas, 1981
 Drosophila umiumi Magnacca & O'Grady, 2009
 Drosophila uncinata Suwito & Watabe, 2010
 Drosophila ungarensis Meijere, 1911
 Drosophila unguicula Okada & Carson, 1983
 Drosophila (Drosophila) unicolor Walker, 1864)
 Drosophila unicula Hardy, 1965
 Drosophila unimaculata Strobl, 1893
 Drosophila uninubes Patterson & Mainland, 1943
单栉果蝇 Drosophila (Sophophora) unipectinata Duda, 1924
 Drosophila unipucntata Patterson, 1943)
 Drosophila unipunctata Patterson, 1943
 Drosophila uniseriata Hardy & Kaneshiro, 1968
 Drosophila uniseta Wasserman, Koepfer & Ward, 1973
 Drosophila unispina Okada, 1956
 Drosophila upoluae Malloch, 1934
 Drosophila urubamba Vilela & Pereira, 1993
 Drosophila usambarensis Lachaise & Chassagnard, 2001
 Drosophila ustulata Meijere, 1908
 Drosophila valenciai Vela & Rafael, 2001
 Drosophila valenteae Llangari Arizo & Rafael, 2018
 Drosophila vallismaia Tsacas, 1984
 Drosophila vanderlindei Ruiz-Fiegalan, 2004
 Drosophila vara Zhang, 2004)
 Drosophila varga Hardy, 1965
 Drosophila variabilis Hardy, 1965
 Drosophila varians Bock & Wheeler, 1972
 Drosophila variegata Grimshaw, 1900
 Drosophila varietas Ranganath & Krishnamurthy, 1972
 Drosophila varietas Singh, 1974
 Drosophila (Drosophila) varipennis Grimshaw, 1901)
 Drosophila velascoi Ruiz-Fiegalan, 2003
 Drosophila velata Hardy, 1965
 Drosophila velox Watabe & Peng, 1991
 Drosophila velutinifrons Hardy, 1965
 Drosophila venezolana Wasserman, Fontdevila & Ruiz, 1983
 Drosophila venusta Hardy, 1965
 Drosophila verticis Williston, 1896
 Drosophila vesciseta Hardy & Kaneshiro, 1968
 Drosophila vescum Lin & Wheeler, 1977
 Drosophila vicaria Hardy, 1965
 Drosophila vicentinae Vilela, 1983
 Drosophila villaatlantica Anonymous, 1948
 Drosophila villitibia Hardy, 1965
 Drosophila (Idiomyia) villosa Hardy, 1965)
 Drosophila villosipedis Hardy, 1965
 Drosophila vinnula Hardy, 1965
 Drosophila (Drosophila) viracochi Brncic & Santibanez, 1957
 Drosophila vireni Bachli, Vilela & Haring, 2002
 Drosophila virilis Sturtevant, 1916
 Drosophila vouidibioi Mercot
 Drosophila vulcana Graber, 1957
 Drosophila vumbae Bock & Wheeler, 1972
 Drosophila waddingtoni Basden, 1976
 Drosophila waddingtoni Hardy
 Drosophila wahihuna Magnacca & O'Grady, 2009
 Drosophila waikamoi Magnacca & O'Grady, 2009
 Drosophila walkeri Evenhuis & Okada, 1989
 Drosophila wangi Toda & Zhang, 1995
 Drosophila warmi Penafiel-Vinueza & Rafael, 2019
 Drosophila wassermani Pitnick & Heed, 1994
 Drosophila watanabei Gupta, 1992
 Drosophila wauana Okada & Carson, 1982
 Drosophila wawae Magnacca & O'Grady, 2009
 Drosophila whartonae Pipkin & Heed, 1964
 Drosophila wheeleri Patterson & Alexander, 1952
 Drosophila wikani Magnacca & O'Grady, 2009
 Drosophila wikstroemiae Magnacca & O'Grady, 2009
 Drosophila williamsi Hardy, 1965
 Drosophila willistoni Sturtevant, 1916
 Drosophila wingei Cordeiro, 1964
 Drosophila xalapa Vilela & Bachli, 2004
 Drosophila xanthia Tsacas, 1981
 Drosophila xanthochroa Tsacas, 2001
黄腹果蝇 Drosophila (Drosophila) xanthogaster Duda, 1924
 Drosophila xanthognoma Hardy, 1965
 Drosophila xanthopallescens Pipkin, 1964
 Drosophila xanthosoma Grimshaw, 1901
 Drosophila xenophaga Kam & Perreira, 2003
 Drosophila xerophila Val, 1983
 Drosophila xiphiphora Pipkin, 1964
 Drosophila xuthoptera Hardy, 1965
 Drosophila yakuba Burla, 1954
 Drosophila yangana Rafael & Vela, 2003
 Drosophila yooni Hardy, 1977
 Drosophila yunnanensis Watabe & Liang, 1990
 Drosophila yuwanensis Kim & Okada, 1988
 Drosophila (Drosophila) z-notatum Bryan, 1934
 Drosophila zamorana Penafiel-Vinueza & Rafael, 2018
 Drosophila zonata Chen & Watabe, 1993
 Drosophila zophea Tsacas, 2004
 Drosophila zottii Vilela, 1983

归入本属的物种：
 Phloridosa lutzii Sturtevant, 1916
 Siphlodora flexa Loew, 1866


參考文獻