Dimethyltryptamine

**Dimethyltryptamine** (**DMT**), also known as ***N_,_N_-dimethyltryptamine** (***N_,_N_-DMT**), is a psychedelic drug from the tryptamine family that is found in nature in many plants and animals. DMT is used as a recreational drug and for spiritual reasons.

DMT works very quickly, has strong hallucinogenic effects, and works for only a few minutes. These reasons mean people in jobs such as businesspeople are known to use it. DMT can be inhaled or injected and its effects are different with different amounts used or different ways of taking it. When inhaled or injected, the effects last about five to fifteen minutes. Effects can last three hours or more when swallowed with a monoamine oxidase inhibitor (MAOI), such as ayahuasca used by Amazonian tribes. DMT causes effects that are hard to describe with words, such as very complex visual hallucinations (seeing things that are not there), changes to senses, ego death. DMT is not addictive but can cause issues for the heart.

## Infobox (drug)

- **verifiedrevid**: 623685269
- **watchedfields**: changed
- **drug name**: Dimethyltryptamine
- **image**: DMT.svg
- **image class**: skin-invert-image
- **width**: 200
- **image2**: DMT-3d-bAll-And-Stickersz-model.png
- **image class2**: bg-transparenT
- **width2**: 200
- **receptors**: At least 13 receptors (e.g., serotonin, sigma, trace amine-associated)
- **precursor**: Tryptophan
- **source tissues**: Central nervous system (exact source tissues are not fully established)
- **target tissues**: Central nervous system
- **routes of administration**: Oral administration, By mouth (usually with an ), inhalation, insufflation, rectal (medicine), rectal, Intramuscular injection, intramuscular, intravenous injection, intravenous
- **class**: Serotonergic psychedelic (hallucinogen)
- **legal au**: S9
- **legal ca**: Schedule III
- **legal uk**: Class A
- **legal us**: Schedule I
- **legal de**: Anlage I
- **legal br**: F2
- **legal un**: P I
- **bioavailability**: Very low and inactive (except with an )
- **metabolism**: Oxidative deamination (), _N_-oxidation, _N_-demethylation, peroxidation
- **metabolites**: * Indole-3-acetic acid (NMT) (63–97%)
* Dimethyltryptamine-N-oxide, DMT-_N_-oxide (DMT-NO) (3–28%)
* N-Methyltryptamine, _N_-Methyltryptamine
* Tryptamine
* Others
- **onset**: * Inhalation: 10–15 seconds
* Intravenous: ≤2–5 min
* Intramuscular injection, Intramuscular: 2–5min
* Oral administration, Oral with : ≤1hour
- **elimination half-life**: * Alone: 5–15min
* With an : 1–4hours
- **duration of action**: * Inhalation: ≤30min
* Intravenous: ≤30min
* Intramuscular injection, Intramuscular: 30–60min
* Oral administration, Oral with : 4–6hours
- **excretion**: Urine
- **cas number**: 61-50-7
- **atc prefix**: None
- **drugbank**: DB01488
- **unii**: WUB601BHAA
- **chebi**: 28969
- **pubchem**: 6089
- **iuphar ligand**: 141
- **chemspiderid**: 5864
- **kegg**: C08302
- **chembl**: 12420
- **pdb ligand**: A1AFV
- **synonyms**: Dimethyltryptamine; DMT; _N_,_N_-DMT
- **iupac name**: 2-(1_H_-Indol-3-yl)-_N_,_N_-dimethylethanamine
- **c**: 12
- **h**: 16
- **n**: 2
- **smiles**: CN(CCC1=CNC2=C1C=CC=C2)C
- **stdinchi**: 1S/C12H16N2/c1-14(2)8-7-10-9-13-12-6-4-3-5-11(10)12/h3-6,9,13H,7-8H2,1-2H3
- **stdinchikey**: DMULVCHRPCFFGV-UHFFFAOYSA-N
- **density**: 1.099
- **melting point**: 40
- **boiling point**: 160
- **boiling notes**: at 
also reported as
 at