julilili42/papers huggingface dataset:
Relevance of Subjective Cognitive Decline in Older Adults with a First-Degree Family History of Alzheimer’s Disease
2022-03-11

Background: It is unclear whether subjective cognitive decline (SCD) is a relevant clinical marker of incipient Alzheimer’s disease (AD) and future cognitive deterioration in individuals with a family history of AD (FHAD). Objective: To investigate the association of SCD with cross-sectional cerebrospinal fluid (CSF) AD biomarker levels and cognitive decline in cognitively normal older adults with or without a first-degree FHAD. Methods: We analyzed data from cognitively normal individuals with first-degree FHAD (n = 82 “AD relatives”; mean age: 65.7 years (SD = 4.47); 59% female) and a similar group of n = 236 healthy controls without FHAD from the DELCODE study. We measured SCD with an in-depth structured interview from which we derived a SCD score, capturing features proposed to increase likelihood of underlying AD (“SCD-plus score”). We tested whether higher SCD-plus scores were associated with more pathological CSF AD biomarker levels and cognitive decline over time and whether this association varied by group. Results: AD relatives showed higher SCD-plus scores than healthy controls and more cognitive decline over time. Higher SCD-plus scores also related stronger to cognitive change and abnormal CSF AD biomarker levels in the AD relatives as compared to the healthy controls group. Conclusion: Quantification of specific SCD features can provide further information on the likelihood of early AD pathology and cognitive decline among AD relatives. FHAD and SCD appear as synergistically acting enrichment strategies in AD research, the first one as a permanent indicator of genetic risk, the latter one as a correlate of disease progression.
Repolarization Precedes Oval Cell–mediated Hepatocytic Regeneration in the CDE Diet Mouse Model
2022-03-11

The liver has a unique ability to recover from injury unlike any other organ. A poorly understood aspect of liver regeneration is the role of hepatocellular polarization. Neighbor of Punc E11 (Nope) is an oncofetal stem/progenitor cell marker, which is expressed by depolarized adult hepatocytes after cholestatic liver injury and in hepatocellular carcinoma. Liver injury induced by a choline-deficient and ethionine-supplemented diet is reversible if followed by an additional dietary stop interval and enabled us to study the expression of Nope during the induction of chronic liver injury and during subsequent liver regeneration. We could show by quantitative RT-PCR, Western blotting, and immunohistochemistry that the expression of Nope is induced in depolarized adult hepatocytes during injury. However, after another 2 weeks of a normal diet, the polarization of hepatocytes was almost completely restored and the expression of Nope remained limited to bile ducts and oval cells. Using an inducible CK19-lineage tracing model, we could demonstrate that oval cell–mediated hepatocyte regeneration is rare and was preceded by repolarization of hepatocytes. In conclusion, polarization of hepatocytes is an important part of liver regeneration and precedes oval cell–mediated regeneration of the liver. This process can be visualized by a characteristic expression pattern of Nope:
Gauge fixing using overrelaxation and simulated annealing on GPUs
2022-03-11

We adopt CUDA-capable Graphic Processing Units (GPUs) for Coulomb, Landau and maximally Abelian gauge fixing in 3+1 dimensional SU(3) lattice gauge field theories. The local overrelaxation algorithm is perfectly suited for highly parallel architectures. Simulated annealing preconditioning strongly increases the probability to reach the global maximum of the gauge functional. We give performance results for single and double precision. To obtain our maximum performance of ~300 GFlops on NVIDIA's GTX 580 a very fine grained degree of parallelism is required due to the register limits of NVIDIA's Fermi GPUs: we use eight threads per lattice site, i.e., one thread per SU(3) matrix that is involved in the computation of a site update.
Euclidean minimal tori with planar ends and elliptic solitons
2022-03-11

A Euclidean minimal torus with planar ends gives rise to an immersed Willmore torus in the conformal 3--sphere . The class of Willmore tori obtained this way is given a spectral theoretic characterization as the class of Willmore tori with reducible spectral curve. A spectral curve of this type is necessarily the double of the spectral curve of an elliptic KP soliton. The simplest possible examples of minimal tori with planar ends are related to 1--gap Lamé potentials, the simplest non--trivial algebro geometric KdV potentials. If one allows for translational periods, Riemann's "staircase" minimal surfaces appear as other examples related to 1--gap Lamé potentials.
Multipole Moments of numerical spacetimes
2022-03-11

In this article we present some recent results on identifying correctly the relativistic multipole moments of numerically constructed spacetimes, and the consequences that this correction has on searching for appropriate analytic spacetimes that can approximate well the previously mentioned numerical spacetimes. We also present expressions that give the quadrupole and the spin octupole as functions of the spin parameter of a neutron star for various equations of state and in a range of masses for every equation of state used. These results are relevant for describing the exterior spacetime of rotating neutron stars that are made up of matter obeying realistic equations of state.
Ricci flows with bursts of unbounded curvature
2022-03-11

Given a completely arbitrary surface, whether or not it has bounded curvature, or even whether or not it is complete, there exists an instantaneously complete Ricci flow evolution of that surface that exists for a specific amount of time [GT11]. In the case that the underlying Riemann surface supports a hyperbolic metric, this Ricci flow always exists for all time and converges (after scaling by a factor ) to this hyperbolic metric [GT11], i.e. our Ricci flow geometrises the surface. In this paper we show that there exist complete, bounded curvature initial metrics, including those conformal to a hyperbolic metric, which have subsequent Ricci flows developing unbounded curvature at certain intermediate times. In particular, when coupled with the uniqueness from [Top13], we find that any complete Ricci flow starting with such initial metrics must develop unbounded curvature over some intermediate time interval, but that nevertheless, the curvature must later become bounded and the flow must achieve geometrisation as , even though there are other conformal deformations to hyperbolic metrics that do not involve unbounded curvature. Another consequence of our constructions is that while our Ricci flow from [GT11] must agree initially with the classical flow of Hamilton and Shi in the special case that the initial surface is complete and of bounded curvature, by uniqueness, it is now clear that our flow lasts for a longer time interval in general, with Shi's flow stopping when the curvature blows up, but our flow continuing strictly beyond in these situations. All our constructions of unbounded curvature developing and then disappearing are in two dimensions. Generalisations to higher dimensions are then immediate.
A projector-splitting integrator for dynamical low-rank approximation
2022-03-11

The dynamical low-rank approximation of time-dependent matrices is a low-rank factorization updating technique. It leads to differential equations for factors of the matrices, which need to be solved numerically. We propose and analyze a fully ex- plicit, computationally inexpensive integrator that is based on splitting the orthogonal projector onto the tangent space of the low-rank manifold. As is shown by theory and illustrated by numerical experiments, the integrator enjoys robustness properties that are not shared by any standard numerical integrator. This robustness can be exploited to change the rank adaptively. Another application is in optimization algorithms for low-rank matrices where truncation back to the given low rank can be done efficiently by applying a step of the integrator proposed here.
Geometric zeta functions for higher rank p-adic groups
2022-03-11

The higher rank Lefschetz formula for p-adic groups is used to prove rationality of a several-variable zeta function attached to the action of a p-adic group on its Bruhat-Tits building. By specializing to certain lines one gets one-variable zeta functions, which then can be related to geometrically defined zeta functions
Fitting the Chandra LETG spectrum of SS Cygni in outburst with model atmosphere spectra
2022-03-11

The Chandra / LETG spectrum of SS Cyg in outburst shows broad (\\approx 5 A) spectral features that have been interpreted as a large number of absorption lines on a blackbody continuum with a temperature of 250 kK (Mauche 2004). It is most probable that this is the spectrum of the fast-rotating optically thick boundary layer on the white dwarf surface. Here we present the results of fitting this spectrum with high gravity hot stellar model atmospheres. An extended set of LTE model atmospheres with solar chemical composition was computed for this purpose. The best fit is obtained with the following parameters: T_eff=190 kK, log g=6.2, and N_H=8 10^{19} cm^{-2}. The spectrum of this model describes the observed spectrum in the 60--125 A range reasonably well, but at shorter wavelengths the observed spectrum has much higher flux. The reasons for this are discussed. The derived low surface gravity supports the hypothesis of the fast rotating boundary layer.
Linear and projective boundary of nilpotent groups
2022-03-11

We define a pseudometric on the set of all unbounded subsets of a metric space. The Kolmogorov quotient of this pseudometric space is a complete metric space. The definition of the pseudometric is guided by the principle that two unbounded subsets have distance 0 whenever they stay sublinearly close. Based on this pseudometric we introduce and study a general concept of boundaries of metric spaces. Such a boundary is the closure of a subset in the Kolmogorov quotient determined by an arbitrarily chosen family of unbounded subsets. Our interest lies in those boundaries which we get by choosing unbounded cyclic sub-(semi)-groups of a finitely generated group (or more general of a compactly generated, locally compact Hausdorff group). We show that these boundaries are quasi-isometric invariants and determine them in the case of nilpotent groups as a disjoint union of certain spheres (or projective spaces). In addition we apply this concept to vertex-transitive graphs with polynomial growth and to random walks on nilpotent groups.
Investigations of a new eclipsing cataclysmic variable HBHA 4705-03
2022-03-11

Results of photometric and spectroscopic investigations of the recently discovered eclipsing cataclysmic variable star HBHA 4705-03 are presented. The emission spectra of the system show broad hydrogen and helium emission lines. The bright spots with an approximately zero velocity components are found in the Doppler maps for the hydrogen and ionized helium lines. The disc structure is more prominent in the maps for the neutral helium lines. The masses of the components (M_WD = 0.54 \\pm 0.10 M_sun and M_RD = 0.45 \\pm 0.05 M_sun), and the orbit inclination (i = 71.8 \\pm 0.^7 deg) were estimated using the radial velocity light curve and the eclipse width. The modeling of the light curve allows us to evaluate the bright spot parameters and the mass accretion rate (\\dot M \\approx 2 10^{17} g s^{-1}).
Finite element approximations of the stochastic mean curvature flow of planar curves of graphs
2022-03-11

This paper develops and analyzes a semi-discrete and a fully discrete finite element method for a one-dimensional quasilinear parabolic stochastic partial differential equation (SPDE) which describes the stochastic mean curvature flow for planar curves of graphs. To circumvent the difficulty caused by the low spatial regularity of the SPDE solution, a regularization procedure is first proposed to approximate the SPDE, and an error estimate for the regularized problem is derived. A semi-discrete finite element method, and a space-time fully discrete method are then proposed to approximate the solution of the regularized SPDE problem. Strong convergence with rates are established for both, semi- and fully discrete methods. Computational experiments are provided to study the interplay of the geometric evolution and gradient type-noises.
Hamiltonian Dyson--Schwinger Equations of QCD
2022-03-11

The general method for treating non-Gaussian wave functionals in the Hamiltonian formulation of a quantum field theory, which was previously developed and applied to Yang--Mills theory in Coulomb gauge, is generalized to full QCD. The Hamiltonian Dyson-Schwinger equations as well as the quark and gluon gap equations are derived and analysed in the IR and UV momentum regime. The back-reaction of the quarks on the gluon sector is investigated.
Identifying a species tree subject to random lateral gene transfer
2022-03-11

A major problem for inferring species trees from gene trees is that evolutionary processes can sometimes favour gene tree topologies that conflict with an underlying species tree. In the case of incomplete lineage sorting, this phenomenon has recently been well-studied, and some elegant solutions for species tree reconstruction have been proposed. One particularly simple and statistically consistent estimator of the species tree under incomplete lineage sorting is to combine three-taxon analyses, which are phylogenetically robust to incomplete lineage sorting. In this paper, we consider whether such an approach will also work under lateral gene transfer (LGT). By providing an exact analysis of some cases of this model, we show that there is a zone of inconsistency for triplet-based species tree reconstruction under LGT. However, a triplet-based approach will consistently reconstruct a species tree under models of LGT, provided that the expected number of LGT transfers is not too high. Our analysis involves a novel connection between the LGT problem and random walks on cyclic graphs. We have implemented a procedure for reconstructing trees subject to LGT or lineage sorting in settings where taxon coverage may be patchy and illustrate its use on two sample data sets.
Spectral curves for Cauchy-Riemann operators on punctured elliptic curves
2022-03-11

We show that one can define a spectral curve for the Cauchy-Riemann operator on a punctured elliptic curve if one imposes appropriate boundary conditions. Algebraic curves of the type thus obtained appear as irreducible components of spectral curves of minimal tori with planar ends in R^3. It appears that these curves coincide with the spectral curves of certain elliptic KP solitons as studied by Krichever.
Bounds for the quantifier depth in finite-variable logics: Alternation hierarchy
2022-03-11

Given two structures and distinguishable in (first-order logic with variables), let denote the minimum alternation depth of a formula distinguishing from . Let be the maximum value of over -element structures. We prove the strictness of the quantifier alternation hierarchy of in a strong quantitative form, namely , which is tight up to a constant factor. For each , it holds that even over colored trees, which is also tight up to a constant factor if . For the last lower bound holds also over uncolored trees, while the alternation hierarchy of collapses even over all uncolored graphs. We also show examples of colored graphs and on vertices that can be distinguished in much more succinctly if the alternation number is increased just by one: while in it is possible to distinguish from with bounded quantifier depth, in this requires quantifier depth . The quadratic lower bound is best possible here because, if and can be distinguished in with quantifier alternations, this can be done with quantifier depth .
Memoryless Near-Collisions, Revisited
2022-03-11

In this paper we discuss the problem of generically finding near-collisions for cryptographic hash functions in a memoryless way. A common approach is to truncate several output bits of the hash function and to look for collisions of this modified function. In two recent papers, an enhancement to this approach was introduced which is based on classical cycle-finding techniques and covering codes. This paper investigates two aspects of the problem of memoryless near-collisions. Firstly, we give a full treatment of the trade-off between the number of truncated bits and the success-probability of the truncation based approach. Secondly, we demonstrate the limits of cycle-finding methods for finding near-collisions by showing that, opposed to the collision case, a memoryless variant cannot match the query-complexity of the "memory-full" birthday-like near-collision finding method.
Lattice Coulomb propagators, effective energy and confinement
2022-03-11

We show that in the lattice Hamiltonian limit all Coulomb gauge propagators are consistent with the Gribov-Zwanziger confinement mechanism, with an IR enhanced effective energy for quarks and gluons and a diverging ghost form factor compatible with a dual-superconducting vacuum. Multiplicative renormalizability is ensured for all static correlators, while for non-static ones their energy dependence plays a crucial role in this respect. Moreover, from the Coulomb potential we can extract the Coulomb string tension σ_C ~ 2 σ.
The vanishing viscosity limit for Hamilton-Jacobi equations on Networks
2022-03-11

For a Hamilton-Jacobi equation defined on a network, we introduce its vanishing viscosity approximation. The elliptic equation is given on the edges and coupled with Kirchhoff-type conditions at the transition vertices. We prove that there exists exactly one solution of this elliptic approximation and mainly that, as the viscosity vanishes, it converges to the unique solution of the original problem.
Hydrodynamic interactions induce anomalous diffusion under partial confinement
2022-03-11

Under partial confinement, the motion of colloidal particles is restricted to a plane but their dynamics is influenced by hydrodynamic interactions mediated by the unconfined, three--dimensional flow of the embedding fluid. We demonstrate that this dimensionality mismatch induces a characteristic divergence in the two--dimensional collective diffusion coefficient of the colloidal monolayer. This result, independent from the specific interparticle forces in the monolayer, is solely due to the kinematical constraint on the colloidal particles, and it is different from the known divergence of transport coefficients in purely two--dimensional fluids.
Multi-frequency study of supernova remnants in the Large Magellanic Cloud. Confirmation of the supernova remnant status of DEM L205
2022-03-11

We present new X-ray and radio data of the LMC SNR candidate DEM L205, obtained by XMM-Newton and ATCA, along with archival optical and infrared observations. We use data at various wavelengths to study this object and its complex neighbourhood, in particular in the context of the star formation activity, past and present, around the source. We analyse the X-ray spectrum to derive some remnant's properties, such as age and explosion energy. Supernova remnant features are detected at all observed wavelengths: soft and extended X-ray emission is observed, arising from a thermal plasma with a temperature kT between 0.2 keV and 0.3 keV. Optical line emission is characterised by an enhanced [SII]/Halpha ratio and a shell-like morphology, correlating with the X-ray emission. The source is not or only tentatively detected at near-infrared wavelengths (&lt; 10 microns), but there is a detection of arc-like emission at mid and far-infrared wavelengths (24 and 70 micron) that can be unambiguously associated with the remnant. We suggest that thermal emission from dust heated by stellar radiation and shock waves is the main contributor to the infrared emission. Finally, an extended and faint non-thermal radio emission correlates with the remnant at other wavelengths and we find a radio spectral index between -0.7 and -0.9, within the range for SNRs. The size of the remnant is ~79x64 pc and we estimate a dynamical age of about 35000 years. We definitely confirm DEM L205 as a new SNR. This object ranks amongst the largest remnants known in the LMC. The numerous massive stars and the recent outburst in star formation around the source strongly suggest that a core-collapse supernova is the progenitor of this remnant. (abridged)
Comment on esurf-2021-78
2022-03-11

<strong class="journal-contentHeaderColor">Abstract.</strong> Frost cracking is a dominant mechanical weathering phenomenon facilitating the breakdown of bedrock in periglacial regions. Despite recent advances in understanding frost cracking processes, few studies have addressed how global climate change over the Late Cenozoic may have impacted spatial variations in frost cracking intensity. In this study, we estimate global changes in frost cracking intensity (FCI) by segregation ice growth. Existing process-based models of FCI are applied in combination with soil thickness data from the Harmonized World Soil Database. Temporal and spatial variations in FCI are predicted using surface temperatures changes obtained from ECHAM5 general circulation model simulations conducted for four different paleoclimate time-slices. Time-slices considered include Pre-Industrial (~1850 CE, PI), Mid-Holocene (~6 ka, MH), Last Glacial Maximum (~21 ka, LGM) and Pliocene (~3 Ma, PLIO) times. Results indicate for all paleoclimate time slices that frost cracking was most prevalent (relative to PI times) in the mid to high latitude regions, as well as high-elevation lower latitudes areas such the Himalayas, Tibet, European Alps, the Japanese Alps, the USA Rocky Mountains, and the Andes Mountains. The smallest deviations in frost cracking (relative to PI conditions) were observed in the MH simulation, which yielded slightly higher FCI values in most of the areas. In contrast, larger deviations were observed in the simulations of the colder climate (LGM) and warmer climate (PLIO). Our results indicate that the impact of climate change on frost cracking was most severe during the PI &ndash; LGM period due to higher differences in temperatures and glaciation at higher latitudes. In contrast, the PLIO results indicate low FCI in the Andes and higher values of FCI in Greenland and Canada due to the diminished extent of glaciation in the warmer PLIO climate.