julilili42/papers huggingface dataset:
Impact of self-esteem and sex on stress reactions
2017-12-04

Abstract Positive self-evaluation is a major psychological resource modulating stress coping behavior. Sex differences have been reported in self-esteem as well as stress reactions, but so far their interactions have not been investigated. Therefore, we investigated sex-specific associations of self-esteem and stress reaction on behavioral, hormonal and neural levels. We applied a commonly used fMRI-stress task in 80 healthy participants. Men compared to women showed higher activation during stress in hippocampus, precuneus, superior temporal gyrus (STG) and insula. Furthermore, men outperformed women in the stress task and had higher cortisol and testosterone levels than women after stress. Self-esteem had an impact on precuneus, insula and STG activation during stress across the whole group. During stress, men recruit regions associated with emotion and stress regulation, self-referential processing and cognitive control more strongly than women. Self-esteem affects stress processing, however in a sex-independent fashion: participants with lower self-esteem show higher activation of regions involved in emotion and stress regulation, self-referential processing and cognitive control. Taken together, our data suggest that men are more engaged during the applied stress task. Across women and men, lower self-esteem increases the effort in emotion and stress processing and cognitive control, possibly leading to self-related thoughts in stressful situations.
Food cleaning in gorillas: Social learning is a possibility but not a necessity
2017-12-04

Food cleaning is widespread in the animal kingdom, and a recent report confirmed that (amongst other behaviours) wild western lowland gorillas also show food cleaning. The authors of this report conclude that this behaviour, based on its distribution patterns, constitutes a potential candidate for culture. While different conceptualisations of culture exist, some more and some less reliant on behavioural form copying, all of them assign a special role to social learning processes in explaining potentially cultural behaviours. Here we report the results of an experiment that tested to what extent food cleaning behaviour in a group of captive Western lowland gorillas (Gorilla gorilla gorilla) relies on social learning processes. Subjects were provided with clean and dirty apples. When they were provided with dirty apples, all subjects showed evidence of food cleaning in at least 75% of trials. Preferred cleaning techniques differed between individuals, four out of five of subjects expressed a behaviour analogous to that reported in wild conspecifics. Given this occurrence of food cleaning in a culturally unconnected population of gorillas, we conclude that social learning is unlikely to play a central role in the emergence of the food cleaning behavioural form in Western lowland gorillas; instead, placing a greater emphasis on individual learning of food cleaning's behavioural form.
Quantitative analysis of O2 and Fe2+ profiles in gradient tubes for cultivation of microaerophilic Iron(II)-oxidizing bacteria
2017-12-04

The classical approach for the cultivation of neutrophilic microaerophilic Fe(II)-oxidizing bacteria is agar-based gradient tubes where these bacteria find optimal growth conditions in opposing gradients of oxygen (O2) and dissolved Fe(II) (Fe2+). The goals of this study were to quantify the temporal development of O2 and Fe2+ concentrations over time, to compare abiotic and microbially inoculated tubes and to test the suitability of different Fe(II)-sources for the cultivation of freshwater and marine microaerophilic Fe(II)-oxidizers. O2 and Fe2+ gradients were monitored on a high spatial resolution as a function of time applying amperometric and voltammetric microsensors. Fe(II)-oxidizers could be cultivated well with FeS and zero-valent iron powder as Fe(II)-source, but FeCO3 and FeCl2 are extremely sensitive for this application. Fe(III) minerals accumulated in inoculated tubes within the first days in regions with an O2 concentration of 20-40 μM and were confirmed to be related to bacterial growth. Microbial Fe(II) oxidation could compete only for the first days with the abiotic reaction after which heterogeneous Fe(II) oxidation, catalyzed by Fe(III) minerals, dominated. Our results imply that transfer of cultures to fresh tubes within 48-72 h is crucial to provide optimal growth conditions for microaerophilic Fe(II)-oxidizers, particularly for the isolation of new strains.
Species selection under long‐term experimental warming and drought explained by climatic distributions
2017-12-04

Summary Global warming and reduced precipitation may trigger large‐scale species losses and vegetation shifts in ecosystems around the world. However, currently lacking are practical ways to quantify the sensitivity of species and community composition to these often‐confounded climatic forces. Here we conducted long‐term (16 yr) nocturnal‐warming (+0.6°C) and reduced precipitation (−20% soil moisture) experiments in a Mediterranean shrubland. Climatic niche groups ( CNG s) – species ranked or classified by similar temperature or precipitation distributions – informatively described community responses under experimental manipulations. Under warming, CNG s revealed that only those species distributed in cooler regions decreased. Correspondingly, under reduced precipitation, a U‐shaped treatment effect observed in the total community was the result of an abrupt decrease in wet‐distributed species, followed by a delayed increase in dry‐distributed species. Notably, while partially correlated, CNG explanations of community response were stronger for their respective climate parameter, suggesting some species possess specific adaptations to either warming or drought that may lead to independent selection to the two climatic variables. Our findings indicate that when climatic distributions are combined with experiments, the resulting incorporation of local plant evolutionary strategies and their changing dynamics over time leads to predictable and informative shifts in community structure under independent climate change scenarios.
Dephosphorylation of the NPR2 guanylyl cyclase contributes to inhibition of bone growth by fibroblast growth factor
2017-12-04

Activating mutations in fibroblast growth factor (FGF) receptor 3 and inactivating mutations in the NPR2 guanylyl cyclase both cause severe short stature, but how these two signaling systems interact to regulate bone growth is poorly understood. Here, we show that bone elongation is increased when NPR2 cannot be dephosphorylated and thus produces more cyclic GMP. By developing an in vivo imaging system to measure cyclic GMP production in intact tibia, we show that FGF-induced dephosphorylation of NPR2 decreases its guanylyl cyclase activity in growth plate chondrocytes in living bone. The dephosphorylation requires a PPP-family phosphatase. Thus FGF signaling lowers cyclic GMP production in the growth plate, which counteracts bone elongation. These results define a new component of the signaling network by which activating mutations in the FGF receptor inhibit bone growth.
Ligand Influence on the Photophysical Properties and Electronic Structures of Tungsten Iodide Clusters
2017-12-04

Compounds containing the [Mo 6 I 8 L 6 ] 2– ion in which L is an inorganic or organic ligand show remarkable photophysical properties. Similar properties were observed for the corresponding compounds based on octahedral tungsten clusters. The properties of these photosensitizers are significantly impacted by the six outer iodide ligands of [W 6 I 8 I 6 ] 2– . To analyze the role of the outer ligands, we prepared and structurally characterized octahedral tungsten cluster compounds with [W 6 I 8 I 6 ] 2– and [M 6 I 8 L 6 ] 2– ions (M = W, Mo; L = para ‐toluenesulfonate). The distinct photophysical properties of the clusters were analyzed with respect to their photoluminescence (i.e., phosphorescence) and luminescence quenching in the presence of molecular oxygen. The electronic structures were analyzed through photoelectron spectroscopy to expose differences in the electronic situations of the compounds.
Paleoenvironmental Research in the Semiarid Lake Manyara Area, Northern Tanzania: A Synopsis
2017-12-04

The Lake Manyara area is the focus of several paleo-archeological investigations. The Manyara basin is located approximately 70 km east of Olduvai Gorge, where important paleoanthropological artifacts are traced back to Homo habilis. In the Manyara basin itself, two hominin-bearing sites (0.78–0.633 Ma) and plenty of vertebrate bones and teeth as well as stone artifacts from different periods were discovered, especially close to the Makuyuni River. Different methodological approaches with a main emphasis on remote sensing were utilized to contribute to the understanding of the paleo-landscape development. In order to investigate the morphotectonic evolution of the study area, lineaments were detected from Synthetic Aperture Radar satellite scenes. The complex lacustrine development of the Lake Manyara and its paleo-stages was investigated by delineating the extent of paleo-lake sediments (older than 0.633 Ma) with multispectral ASTER data. In addition, lake terraces and shorelines on different levels (up to 80 m above today's lake level) and an outlet to the neighboring Engaruka basin were detected by analyzing the backscattered intensity of TerraSAR-X data. The distribution of topsoils, identified from multisensory remote sensing datasets, indicates soil formation as well as erosional and depositional processes. The fossils and artifacts were then characterized, and their distribution probabilities were determined using a statistical model. The proposed methods contribute to a better understanding of the paleoenvironmental interrelations within the study area.
Japanese Style Management
2017-12-04

Like any other management model, Japanese style management is also in constant flux, as it has to adapt to a changing competitive environment. However, the Japanese management model in particular has been under a significant amount of pressure to change since its glory days in the 1980s. This was in order to respond to the economic malaise in Japan, which started in the early 1990s. This entry presents key characteristics of the traditional Japanese style management and describes the opposing pressures of change and continuity under which it has since evolved.
Industrial/Postindustrial Society
2017-12-04

The term “industrial society” covers a historical categorization of the industrial mode of social reproduction, in addition to sociological theories on the social conditions and consequences of industrial development. The history of such theories extends from the early nineteenth century (Saint‐Simon, Marx, Spencer) to the 1960s (Rostow, Aron, Galbraith). Theories of “postindustrial society” became influential in the last third of the twentieth century. They focus on the growth of services, the increasing role of knowledge work, and digital information technologies and their social consequences; leading authors are Bell, Beck, Giddens, and Castells.
Nerve ultrasound in polyneuropathies
2017-12-05

ABSTRACT Ultrasound can be used to visualize pathology in the peripheral nerves of patients with polyneuropathy. Nerve enlargement is the most frequent pathology, but other abnormalities, including abnormal nerve echogenicity and vascularity, are also encountered. This monograph presents an overview of the role of nerve ultrasound in the evaluation and management of both inherited and acquired polyneuropathies. A description of the sonographic techniques and common abnormalities is provided, followed by a presentation of typical findings in different neuropathies. Scoring systems for characterizing the presence and pattern of nerve abnormalities as they relate to different polyneuropathies are presented. Muscle Nerve 57 : 716–728, 2018
DNAAF1 links heart laterality with the AAA+ ATPase RUVBL1 and ciliary intraflagellar transport
2017-12-05

DNAAF1 (LRRC50) is a cytoplasmic protein required for dynein heavy chain assembly and cilia motility, and DNAAF1 mutations cause primary ciliary dyskinesia (PCD; MIM 613193). We describe four families with DNAAF1 mutations and complex congenital heart disease (CHD). In three families, all affected individuals have typical PCD phenotypes. However, an additional family demonstrates isolated CHD (heterotaxy) in two affected siblings, but no clinical evidence of PCD. We identified a homozygous DNAAF1 missense mutation, p.Leu191Phe, as causative for heterotaxy in this family. Genetic complementation in dnaaf1-null zebrafish embryos demonstrated the rescue of normal heart looping with wild-type human DNAAF1, but not the p.Leu191Phe variant, supporting the conserved pathogenicity of this DNAAF1 missense mutation. This observation points to a phenotypic continuum between CHD and PCD, providing new insights into the pathogenesis of isolated CHD. In further investigations of the function of DNAAF1 in dynein arm assembly, we identified interactions with members of a putative dynein arm assembly complex. These include the ciliary intraflagellar transport protein IFT88 and the AAA+ (ATPases Associated with various cellular Activities) family proteins RUVBL1 (Pontin) and RUVBL2 (Reptin). Co-localization studies support these findings, with the loss of RUVBL1 perturbing the co-localization of DNAAF1 with IFT88. We show that RUVBL1 orthologues have an asymmetric left-sided distribution at both the mouse embryonic node and the Kupffer's vesicle in zebrafish embryos, with the latter asymmetry dependent on DNAAF1. These results suggest that DNAAF1-RUVBL1 biochemical and genetic interactions have a novel functional role in symmetry breaking and cardiac development.
Impact of helmet use in equestrian-related traumatic brain injury: a matched-pairs analysis
2017-12-05

Under consideration of comparable trauma mechanisms, horseback riders that do not wear a safety helmet are at risk to suffer significantly more severe brain injury than helmeted riders. Therefore, safety helmets are recommendable for all horseback riders.
Chiral separation of disease biomarkers with 2‐hydroxycarboxylic acid structure
2017-12-05

Abstract Chiral 2‐hydroxycarboxylic acids are compounds that have been linked to particular diseases and are putative biomarkers with some diagnostic potential. The importance of identifying whether a particular enantiomer is related to certain diseases has been encouraged recently. However, in many cases it has not yet been elucidated whether there are stereochemical implications with respect to these biomarkers and whether their enantioselective analysis provides new insights and diagnostic potential. In this study 13 disease‐related chiral 2‐hydrocarboxylic acids were studied for their chiral separation by high‐performance liquid chromatography on three cinchona alkaloid‐derived chiral stationary phases. From a subgroup of eight 2‐hydroxymonocarboxylic acids, baseline resolution could be achieved and inversion of elution order by exchanging tert ‐butylcarbamoyl quinidine chiral stationary phase (Chiralpak QD‐AX) for the corresponding quinine analogue (Chiralpak QN‐AX) is shown for seven of them. Furthermore, conditions for chiral separation of the 2‐hydroxydicarboxylic acids, citramalic acid, 2‐isopropylmalic acid, and 2‐hydroxyadipic acid are reported and compared to the previous reported conditions for 2‐hydroxyglutaric acid and malic acid.
VITO
2017-12-05

demonstration Share on VITO: Virtual Testbed Orchestration for Automation of Networking Experiments Authors: Andreas Stockmayer Chair of Communication Networks, University of Tuebingen, Tuebingen, Germany Chair of Communication Networks, University of Tuebingen, Tuebingen, GermanyView Profile , Christian Kindermann Chair of Communication Networks, University of Tuebingen, Tuebingen, Germany Chair of Communication Networks, University of Tuebingen, Tuebingen, GermanyView Profile , Michael Menth Chair of Communication Networks, University of Tuebingen, Tuebingen, Germany Chair of Communication Networks, University of Tuebingen, Tuebingen, GermanyView Profile Authors Info & Claims VALUETOOLS 2017: Proceedings of the 11th EAI International Conference on Performance Evaluation Methodologies and ToolsDecember 2017 Pages 113–118https://doi.org/10.1145/3150928.3150954Published:05 December 2017Publication History 1citation45DownloadsMetricsTotal Citations1Total Downloads45Last 12 Months3Last 6 weeks1 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Metal Artifact–Free and Dose-Efficient Computed Tomography Imaging of a Cardiac Prosthetic Valve Using Spectral Shaping of the X-ray Beam: A Case Report
2017-12-05

Abstract Bioprosthetic valve (BPV) thrombosis can be challenging to diagnose with cardiac computed tomography owing to metal artifacts of the BPV. In this case report, an optimized metal artifact reduction protocol using a third-generation dual-source multidetector computed tomographic scanner with high kVp (Sn150kVp) and tin (Sn) filtration and high temporal resolution yielded high-quality, artifact-free, dynamic images of a thrombosed mitral BPV.
Hamiltonian approach to QCD in Coulomb gauge: Gribov’s confinement scenario at work
2017-12-05

\\nI will review essential features of the Hamiltonian approach to QCD in Coulomb gauge showing that Gribov's confinement scenario is realized in this gauge. For this purpose I will discuss in detail the emergence of the horizon condition and the Coulomb string tension. I will show that both are induced by center vortex gauge field configurations, which establish the connection between Gribov’s confinement scenario and the center vortex picture of confinement. I will then extend the Hamiltonian approach to QCD in Coulomb gauge to finite temperatures, first by the usual grand canonical ensemble and second by the compactification of a spatial dimension. I will present results for the pressure, energy density and interaction measure as well as for the Polyakov loop.\\n
Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer's disease
2017-12-05

The molecular architecture of amyloids formed in vivo can be interrogated using luminescent conjugated oligothiophenes (LCOs), a unique class of amyloid dyes. When bound to amyloid, LCOs yield fluorescence emission spectra that reflect the 3D structure of the protein aggregates. Given that synthetic amyloid-β peptide (Aβ) has been shown to adopt distinct structural conformations with different biological activities, we asked whether Aβ can assume structurally and functionally distinct conformations within the brain. To this end, we analyzed the LCO-stained cores of β-amyloid plaques in postmortem tissue sections from frontal, temporal, and occipital neocortices in 40 cases of familial Alzheimer's disease (AD) or sporadic (idiopathic) AD (sAD). The spectral attributes of LCO-bound plaques varied markedly in the brain, but the mean spectral properties of the amyloid cores were generally similar in all three cortical regions of individual patients. Remarkably, the LCO amyloid spectra differed significantly among some of the familial and sAD subtypes, and between typical patients with sAD and those with posterior cortical atrophy AD. Neither the amount of Aβ nor its protease resistance correlated with LCO spectral properties. LCO spectral amyloid phenotypes could be partially conveyed to Aβ plaques induced by experimental transmission in a mouse model. These findings indicate that polymorphic Aβ-amyloid deposits within the brain cluster as clouds of conformational variants in different AD cases. Heterogeneity in the molecular architecture of pathogenic Aβ among individuals and in etiologically distinct subtypes of AD justifies further studies to assess putative links between Aβ conformation and clinical phenotype.
Targeted vs systematic robot‐assisted transperineal magnetic resonance imaging‐transrectal ultrasonography fusion prostate biopsy
2017-12-06

Objective To evaluate the performance of transperineal robot‐assisted ( RA ) targeted ( TB ) and systematic ( SB ) prostate biopsy in primary and repeat biopsy settings. Patients and Methods Patients underwent RA biopsy between 2014 and 2016. Before RA ‐ TB , multiparametric magnetic resonance imaging (mp MRI ) was performed. Prostate lesions were scored (Prostate Imaging, Reporting and Data System, version 2) and used for RA ‐ TB planning. In addition, RA ‐ SB was performed. Available, whole‐gland pathology was analysed. Results In all, 130 patients were biopsy naive and 72 had had a previous negative transrectal ultrasonography‐guided biopsy. In total, 202 patients had suspicious mp MRI lesions. Clinically significant prostate cancer was found in 85% of all prostate cancer cases ( n = 123). Total and clinically significant prostate cancer detection rates for RA ‐ TB vs RA ‐ SB were not significantly different at 77% vs 84% and 80% vs 82%, respectively. RA ‐ TB demonstrated a better sampling performance compared to RA ‐ SB (26.4% vs 13.9%; P &lt; 0.001). Conclusion Transperineal RA ‐ TB and ‐ SB showed similar clinically significant prostate cancer detection rates in primary and repeat biopsy settings. However, RA ‐ TB offered a 50% reduction in biopsy cores. Omitting RA ‐ SB is associated with a significant risk of missing clinically significant prostate cancer.
Stone heat treatment in the Early Mesolithic of southwestern Germany: Interpretation and identification
2017-12-06

The Early Mesolithic of southwestern Germany, the so-called Beuronian (9600-7100 BC), is a period of important transformations in the way people lived, in their subsistence and in the stone tools they produced. One of the perhaps most spectacular re-inventions of that time is heat treatment of stones prior to their manufacture into tools. Although heat treatment has been understood as one of the defining characteristics of the Beuronian of southwestern Germany, and although its existence has been known for almost 30 years now, relatively few systematic studies on it are available. In this paper, we present such a study, aiming to shed light on two questions: (1) what technique and heating parameters were used in the Beuronian and (2) how reliable are the macroscopic proxies traditionally used to identify heat treatment in this context? We investigate these questions using a non-destructive archaeometric technique for measuring past heating temperatures of heat-treated stones and a quantitative surface roughness analysis aiming to understand the relations between surface aspect and heat treatment. These methods are applied to 46 Jurassic chert artefacts from the site Helga-Abri located in the Swabian Alb region of southwestern Germany. Our results document that an opportunistic low-investment procedure was used to heat stone, probably relying on the use of the above-ground part of regular camp-fires. We also found that the traditionally used macroscopic criteria, such as colour and surface gloss, cannot be unambiguously used to identify heat treatment in assemblages made from Jurassic chert. These findings have important implications for our understanding of the Beuronian lithic chaîne opératoire in terms of the investment in time and resources necessary, and for the refinement of archaeological techniques used to identify heat treatment in the Mesolithic of the Swabian Alb.