julilili42/papers huggingface dataset:
Does prolonged exhausting exercise influence the immune system in solid organ transplant recipients?
2008-01-01

Exhausting endurance exercise exhibits strong effects on the immune system (1). Such effects have been attributed to changes in the cellular composition of peripheral blood as well as to changes in the expression of plausible candidate genes (2,3). The role of exhaustive exercise in transplant candidates is unclear up to now and of great interest for the transplant society. After organ transplantation the immune system is strongly affected by the life-long required immunosuppressive medication. There are numerous sport events and even Olympic games for transplant recipients. The Euregio cycling tour is a successfully performed yearly event for transplant patients and takes place in Austria/Italy. The tour lasts 3 days, leads through the Austrian/Italian Alps and total distance is about 330 km (day one: 140 km, day two: 90 km, day 3: 102 km). In the last tour in June 2008 60 cyclists (doctors, nurses, friends) and 22 transplant recipients (19 men/3 woman) who had been successfully transplanted for liver, heart or renal failure participated successfully. All of them were under stable immunosuppression and had normal organ function. All participants and especially patients were able to finish the race within the 3 days and suffered from no major physical problems during and after the tour. We think that this event touches a new field of exercise related research and plan to do microarray analysis on the next tour in 2009 to find a list of candidate genes which might help to monitor the immunological response to exercise in this special condition as compared to healthy subjects. With this letter we like to bring this to the attention of the international community of scientists working in the area of exercise immunology. We would welcome any suggestion for cooperation in this field from other countries and continents.
["Is it an animal inside? "Melanie Klein's unpublished Don Juan Paper (1939)].
2008-01-01

Klein had been asked to contribute an article to the birthday number of the International Journal for Jones. The author outlines how she hurriedly wrote a text about Don Juan which, however, was rejected by the editor. Essential parts of it are presented in German translation. The manuscript is discussed in the context of Klein's published work as well as of the relevant contemporary literature. In Klein's view, Don Juan's genitality is determined by oral impulses and fears. By his manic acting out he attempts to ward off a depressive break-down. The paper ends with some reflections about why Klein--ontrary to her intention--failed to revise her manuscript for later publication.
Modulating TGF-β Receptor Signaling: A Novel Approach of Cancer Therapy
2008-01-01

Transforming growth factor-β (TGF-β) is a member of a superfamily of cytokines involved in many biological processes in both normal and cancer cells. The effects of TGF-β include the regulation of growth and proliferation, the migration and invasiveness of cells as well as cell survival and death. Beside these TGF-β effects in adult mammalian organisms, TGF-β is involved in the specification of cell fate during embryogenesis. Deregulation of the TGF-β-signaling cascade is a common process in many diseases, notably cancer. Although TGF-β may acts as a tumor suppressor in the early pathogenesis of some cancers such as colon cancer, it becomes a malignancy-associated cytokine during tumor progression both because of autocrine and paracrine, mostly immunosuppressive effects. Blocking the TGF-β-signaling pathway is therefore a promising approach of cancer therapy. Preclinical studies of blocking TGF-β signaling in tumor or immune cells by expressing soluble TGF-β receptors or by inhibiting the intracellular TGF-β signaling cascade via blocking the kinase activity of the ligand/receptor complex have shown promise in a variety of different tumor models. In contrast to soluble TGF-β receptors, dominant-negative, kinase-dead versions of TGF-β receptors (dnR) show ambilateral effects. While dnR might block autocrine TGF-β effects such as tumor cell motility in cancer cells, dnR expression in normal lymphocytes or breast cells may also lead to a more aggressive tumor growth by indirect or direct mechanisms, respectively. Altogether these observations from animal models demonstrate both the potential value and the risks of targeting TGF-β as a therapeutic approach to cancer. At present, small molecules blocking the intracellular TGF-β signaling cascade are probably the most promising therapeutics in the treatment of cancers which depend on enhanced TGF-β activity.
Shakespeare Translation in France and Germany in the 1950s: a Comparison
2008-01-01

The article investigates the role of Shakespeare translation for post-war cultural development in France and the two Germanys in the 1950s. It shows a marked contrast between the French and the German case, which is interpreted in terms of the respective Shakespearian traditions in the two cultures.&#13;\\n&#13;\\nThroughout the 1950s, German Shakespeare translation continues to be enmeshed in the past: there are only individual attempts at new Shakespeare translations, whereas, both in terms of publications and of critical reception, the Schlegel-Tieck version continues to dominate. This situation seems to attest to an inability, or an unwillingness, to break with the tradition and, in particular, to question the close relationship between German nationalism and Shakespeare reception that had obtained in the past. Hence, Shakespeare translation in 1950s’ Germany appears as a reinforcement of a traditional German identity, rather than as an active cultural renewal.&#13;\\n&#13;\\nConversely, through novel translations, 1950s’ France sees a renewed dialogue with the English Bard. Building on an enhanced translation activity in the first half of the 20th century, Shakespeare translation represents a seat of cultural dynamism and renewal. There are collaborative translation projects (such as the edition in the Club français du livre) and, not least because of the way in which young creative writers are involved in these enterprises, Shakespeare translation in the 1950s constitutes a motor for French cultural development in general.
Acquisition of a New Type of Lexical-Semantic Relation from German Corpora
2008-01-01

In this paper we will report on work in progress towards increasing the relational density of the German wordnet. It is also an experiment in corpus-based lexical acquisition. The source of the acquisition is a large corpus of German newspaper texts. The target is the German wordnet (GermaNet). We acquire a new type of lexical-semantic relation, i.e. the relation between the verbal head of a predicate and the nominal head of its argument. We investigate how the insertion of instances of this relation into the German wordnet GermaNet affects the neighbourhood of the nodes which are connected by an instance of the new relation. Special attention is given in this paper to the language-specific aspects of the acquisition process.
First report of the Dutch-German Ross Registry – the pulmonary homograft in 1162 patients
2008-01-01

Aims: The Ross operation presents with favourable postoperative hemodynamics and clinical results. Usage of a pulmonary homograft (HG) is associated with an elevated risk of valve substitute pathology. This study was conducted in order to evaluate the clinical development of the HG in a large international Ross operated cohort.
Dan Hicks and Mary C. Beaudry (eds), The Cambridge Companion to Historical Archaeology. (Cambridge: Cambridge University Press, 2006, 404 pp., 31 figs, 1 table, ISBN (hbk) 978 0 521 85375 0, (pbk) 978 0 521 61962 2)
2008-01-01

Dan Hicks and Mary C. Beaudry (eds), The Cambridge Companion to Historical Archaeology. (Cambridge: Cambridge University Press, 2006, 404 pp., 31 figs, 1 table, ISBN (hbk) 978 0 521 85375 0, (pbk) 978 0 521 61962 2) - Volume 11 Issue 2-3
siRNA-mediated silencing of leukocyte endothelial interactions – A gleam of hope for quality improvement in venous bypass grafts?
2008-01-01

Objectives: Transendothelial migration of leukocytes mediated by adhesion molecules promotes venous bypass failure by increasing neointimal thickening and rapid progressive atherosclerosis. The discovery of short interfering RNA (siRNA) opens new perspectives towards non-viral silencing of adhesion molecules on the vascular wall of venous bypass grafts. This study deals with the power of siRNA to transiently block leukocyte-endothelial interactions in a dynamic flow model in order to prevent leukocyte migration in an early stage.
The fate of the bicuspid aortic valve in Ross partients
2008-01-01

Objectives: Patients with a bicuspid aortic valve (BAV) often present with aortic root and ascending aorta pathology. Usage of the Ross operation in this subgroup of pts remains controversial regarding the development of aortic regurgitation (AR) and aortic root dimensions (ARD). Comparing BAV and non-BAV with respect to AR and ARD has rarely been performed.
Combined osteosynthetic chest stabilization and bilateral horizontal sliding flap – a promising concept for ventral chest reconstruction in complicated cases
2008-01-01

Objective: Deep sternal wound infection (DSWI) leading to postoperative mediastinitis is a devastating complication of cardiac surgery, especially after usage of internal mammarian arteries. Standard wire-circlage may result in complex sequestrated sternal edge bone fragments in some cases. Definite stable chest closure remains a demanding challenge.
Screening in the bremsstrahlung reactions and determination of the magnetic moment of the Δ resonance
2008-01-01

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation A. I. Machavariani; Screening in the bremsstrahlung reactions and determination of the magnetic moment of the Δ resonance. AIP Conf. Proc. 31 August 2008; 1030 (1): 141–146. https://doi.org/10.1063/1.2973489 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
Nanoscale Characterization of Single Metal Nanoparticles by their Scattering Patterns
2008-01-01

We used confocal interference scattering microscopy combined with higher order laser modes to determine the position, the shape, the orientation and the effect of the environment on individual metal nanoparticles by studying their scattering patterns.
Exploiting graph structure for accelerating the calculation of shortest paths in WordNets
2008-01-01

This paper presents an approach for substantially reducing the time needed to calculate the shortest paths between all concepts in a wordnet. The algorithm exploits the unique "star-like" topology of wordnets to cut down on time-expensive calculations performed by algorithms to solve the all-pairs shortest path problem in general graphs. The algorithm was applied to two wordnets of two different languages: Princeton WordNet (Fellbaum, 1998) for English, and GermaNet (Kunze and Lemnitzer, 2002), the German language wordnet. For both wordnets, the time needed for finding all shortest paths was brought down from several days to a matter of minutes.
Blockade of the platelet GP IIb/IIIa receptor versus selective inhibition of platelet signal transduction: Which approach is better to protect platelets during extracorporeal circulation?
2008-01-01

Introduction: Blood contact with extracorporeal circulation (ECC) and hypothermia as used in cardiac surgery cause platelet dysfunction possibly followed by severe bleeding. Platelet glycoprotein (GP) IIb/IIIa blockers protect platelets during ECC but may cause prolonged platelet inhibition and platelet activation. An alternative may be selective inhibition of platelet signal transduction using the new phosphoinositide-3-kinase-p110β inhibitor TGX-221 that inhibits shear-induced platelet activation without affecting the bleeding time.
Influence of rhDNAse on the duration of mechanical ventilation in intensive care patients
2008-01-01

rhDNase is effective in the treatment of children with cystic fibrosis [1]. Significant reduction of the duration of ventilation by rhDNAse has been reported in children following cardiac surgery [2]. The goal of the present study was to investigate whether rhDNase is able to reduce the duration of ventilation in adult mechanically ventilated intensive care patients.
SPP1148 booth: Coarse-grained reconfiguration
2008-01-01

In the last years, aside from fine-grained reconfigurable architectures such as FPGAs, coarse-grained reconfigurable architectures (CGRAs), which typically have building blocks of a fixed bit-width (8 bit, 16 bit, etc.), have gained in importance in academia as well as in industry. CGRAs are usually used for domain-specific computations and have advantages over traditional FPGAs in terms of area and power cost, performance, and reconfiguration time. Thus, architectures with coarse-grained reconfiguration features have also been studied in projects (Sec. 1, 2, 4) within the priority program Reconfigurable Computing Systems and the project CoMap (Sec. 3), which are all sponsored by the German science foundation.
NUMERICAL MODELING OF HEAT STORAGE IN SOILS
2008-01-01

In this paper we present a numerical model for the simulation of non-isothermal air flow and corresponding heat transport in the unsaturated soil zone. The governing equations for non-isothermal gas flow and related heat transport are derived. The thermo-hydraulic (TH) coupling is additionally due to material properties, such as density, viscosity, heat diffusivity, which depends on the primary variables air pressure and temperature. A finite element model is developed for the solution of the resulting initial-boundary-value-problem. The numerical model is verified against analytical solutions for simplified problems. Finally, a case study for heat storage in soils is conducted.
GPU Color Constancy
2008-01-01

Abstract A sensor located inside a digital camera is only able to measure the light that is reflected by an object. The reflected light varies with the spectral power distribution of the illuminant. Hence, images taken with a digital camera may show a strong color cast if an incorrect white balance setting has been chosen. Such a color cast may also be due to an automatic white balance not working correctly. In contrast, colors perceived by a human observer appear to be approximately constant. Algorithms for automatic white balance try to mimic this ability and compute a color-corrected image that appears to have been taken under an illuminant with a uniform power distribution. I show how color-constancy algorithms can be implemented very efficiently on modern graphics processing units.
Application of Discrete Differential Forms in numerical General Relativity
2008-01-01

Applications of Discrete Differential Forms in numerical GR are described. The motivation to use this finite element method is its manifest coordinate independence. It is discussed how numerical schemes based on this method were developed and results of simulations for spherically symmetric vacuum space-times are presented.
Comparison of gait data using two different protocols for ankle joint kinematics
2008-01-01

Gait analysis is an important instrument in various fields of clinical research and its protocols are intended to make kinematics interpretable for clinicians. Although they use the same nomenclature for joint angles, different protocols produce different results [1]. The purpose of this study was to compare gait events of the ankle joint to determine differences between two protocols.
Quantifying the Efficiency of the Xetra LOB Market A Detailed Recipe
2008-01-01

Motivated by the prominent role of electronic limit order book (LOB) markets in today’s stock market environment, this paper provides the basis for understanding, reconstructing and adopting Hollifield, Miller, Sandas, and Slive’s (2006) (henceforth HMSS) methodology for estimating the gains from trade to the Xetra LOB market at the Frankfurt Stock Exchange (FSE) in order to evaluate its performance in this respect. Therefore this paper looks deeply into HMSS’s base model and provides a structured recipe for the planned implementation with Xetra LOB data. The contribution of this paper lies in the modification of HMSS’s methodology with respect to the particularities of the Xetra trading system that are not yet considered in HMSS’s base model. The necessary modifications, as expressed in terms of empirical caveats, are substantial to derive unbiased market efficiency measures for Xetra in the end.
CNS infections: progress in therapy, diagnosis, and prevention
2008-01-01

18 http://neurology.thelancet.com Vol 7 January 2008 Patients with suspected community-acquired bacterial meningitis are commonly treated with dexamethasone, vancomycin, and a cephalosporin; vancomycin is included in case the meningitis is due to a cephalosporin-resistant strain of Streptococcus pneumoniae. However, because penetration of vancomycin through the blood–brain barrier is enhanced by meningeal infl ammation, there has been concern that the anti-infl ammatory properties of dexamethasone might limit concentrations of vancomycin in the CSF. In a prospective study, Ricard and colleagues measured vancomycin concentrations in the serum and CSF of adults in medical intensive care units who had confi rmed pneumococcal meningitis and who were treated with dexamethasone and intravenous antibiotics including vancomycin (60 mg/kg per day after a loading dose of 15 mg/kg). After a few days, the mean concentration of vancomycin in CSF was four to ten times greater than the minimal inhibitory concentration of vancomycin for S pneumoniae. Eight of the 13 patients survived and were discharged from hospital with normal neurological status, and the high dose of vancomycin was well tolerated. This study supports previous reports that intravenous vancomycin can achieve adequate concentrations in the CSF when dexamethasone is used as an adjunctive agent. Ricard and colleagues recommend that vancomycin should be given at 45–60 mg/kg per day in an 8 h dosing interval. Tests to detect infecting organisms in CSF include stain and culture, PCR, and antigen and antibody studies. The detection of virus-specifi c or bacteriaspecifi c IgM in CSF is defi nitive evidence that the organism has caused the CNS infection, whereas the detection of an IgG is not defi nitive because IgG can transfer passively from serum to CSF. Detection of antibodies to Borrelia burgdorferi in CSF has been regarded as defi nitive evidence of neurological Lyme disease on the assumption that the presence of antibodies in the CSF is proof of intrathecal antibody production. However, the passive transfer from serum and the fact that Lyme antibodies can persist in the CSF for years mean that intrathecal production cannot be confi rmed by detection of IgG in CSF alone. Blanc and colleagues used an antibody index of the ratio of the concentration of anti-Borrelia IgG in CSF divided by that in serum to the total concentration of IgG in CSF divided by that in serum; the result is positive when the ratio is greater than 2. This antibody CNS infections: progress in therapy, diagnosis, and prevention Ingeborg Krageloh-Mann University Children’s Hospital, Department of Paediatric Neurology and Developmental Medicine, Hoppe-Seyler-Strasse 1, D-72076 Tubingen, Germany ingeborg.kraegeloh-mann@med.uni-tuebingen.de
Severe hypoxia and multiple infarctions resembling Creutzfeldt-Jakob disease.
2008-01-01

Although neuropathological examination is still required for the definite diagnosis of Creutzfeldt-Jakob disease (CJD), specialised clinical assessment predicts probable CJD. Here we present a 73-year-old female patient presenting with rapid cognitive decline, visual, acoustic and cerebellar disturbances, ataxia and EEG changes compatible with early CJD stages. MRI revealed hyperintensities within the thalami, hypothalami, corpora mammillaria, the tectum and the cortex. Initial neuropathological examination showed severe cortical and subcortical spongiosis. However, both immunohistochemistry and Western blotting showed no pathological prion protein. Finally, small infarctions affecting the tectum, tegmentum, corpora mammillaria and global hypoxic-ischaemic changes could be identified as the probable reason for the changes interpreted as CJD-related pathology. Hypoxic-ischaemic CNS alterations mainly affecting the supply area of the basilar artery should be ruled out in case of probable CJD. In addition, severe spongiosis can be misleading in the histological examination, suggesting the diagnosis of a prion-induced spongiform encephalopathy.
Modeling and forecasting return volatility: A new reduced form approach using nonparametric variation measures
2008-01-01

This paper motivates a reduced form discrete-time series approach that models realized volatility by using its separated components, continuous variation and variation due to jumps. For this purpose, I combine Engle and Russell’s (1998) autoregressive conditional duration (ACD) model applied to the continuous and jump size variation with
Unemployment and other forms of social exclusion : job loss and its consequences on civic engagement in Germany and Great Britain
2008-01-01

"This article addresses the relationship between unemployment and other forms of social exclusion. More specifically, it deals with the consequences of job loss on the participation in civic engagement, comparing the situation in Germany and Great Britain. Building on previous research which has shown that the unemployed are less engaged in volunteer work, the study investigates whether the decline of civic engagement is really a consequence of unemployment in the sense that people who lose their jobs give up their civic engagement. Special attention is given to the logic of the situation in which an unemployed person decides to give up or take\\nup volunteering activities: Firstly, I argue that the use of volunteering as a job search strategy is related to early phases of unemployment while it is used as an alternative to paid employment in later stages of unemployment. Secondly, the article tests the assumption uttered by feminist authors that women are more inclined to accept unpaid volunteer work as a valuable alternative to paid employment. Thirdly, the study shows that the effect of job loss on volunteering behaviour cannot be understood independently from the institutional surrounding,\\nnamely the degree of labour market regulation in a country. The article presents empirical findings from the multivariate analysis of longitudinal panel data in Germany (GSOEP) and Great Britain (BHPS)." (author's abstract)
Neutron Stars In Modified Theories Of Gravity
2008-01-01

Modified theories of gravity have had recent success in explaining various phenomena without the need for dark matter. In particular, Bekenstein’s Tensor-Vector-Scalar theory (TeVeS) has been able to explain gravitational lensing, galaxy rotation curves and the Tully-Fisher relation, and also cosmological scenarios such as being able to reproduce key features of the power spectra of the cosmic microwave background and galaxy distributions. However, these phenomena all occur in the weak-field regime. In the strong-field, various black hole solutions have been discovered and investigated. However, to date there has been no work on analytic solutions of the equations of hydrostatic equilibrium. We provide a brief overview of the TeVeS theory including its successes and shortcomings, and also derive the TeVeS equations of hydrostatic equilibrium. By imposing realistic equations of state on the equations we can determine various properties regarding neutron stars. This provides a possible testing ground for deviations from General Relativity.