julilili42/papers huggingface dataset:
Knowledge Growth, Academic Beliefs and Motivation of Students in Business and Economics - A longitudinal German Case Study
2018-03-18

In this study we examine the determinants of and the relationship among economic knowledge, epistemological beliefs, and extrinsic and intrinsic motivation over the course of undergraduate studies in a sample of students of business and economics at a university in Germany. We found economic knowledge increased over the course of studies, extrinsic and intrinsic motivation declined, and students became more skeptical in their epistemological beliefs about the objectivity of economic content being taught in their courses. The students’ level of economic knowledge was related to intrinsic motivation but unrelated to extrinsic motivation and epistemological beliefs. Furthermore, the students’ tendency to become more skeptical over the course of their studies was mitigated by high levels of extrinsic motivation. The use of internationally established assessments such as the Test of Economic Literacy, developed by the Council of Economics Education, enables implications for higher education business and economics programs at the international level to be drawn from our findings.
Accelerating infall and rotational spin-up in the hot molecular core G31.41+0.31
2018-03-19

As part of our effort to search for circumstellar disks around high-mass stellar objects, we observed the well-known core G31.41 +0.31 with ALMA at 1.4 mm with an angular resolution of ~0.′′22 (~1700 au). The dust continuum emission has been resolved into two cores namely Main and NE. The Main core, which has the stronger emission and is the more chemically rich, has a diameter of ~5300 au, and is associated with two free-free continuum sources. The Main core looks featureless and homogeneous in dust continuum emission and does not present any hint of fragmentation. Each transition of CH 3 CN and CH 3 OCHO, both ground and vibrationally excited, as well as those of CH 3 CN isotopologues, shows a clear velocity gradient along the NE–SW direction, with velocity linearly increasing with distance from the center, consistent with solid-body rotation. However, when comparing the velocity field of transitions with different upper level energies, the rotation velocity increases with increasing energy of the transition, which suggests that the rotation speeds up toward the center. Spectral lines towardtoward the dust continuum peak show an inverse P-Cygni profile that supports the existence of infall in the core. The infall velocity increases with the energy of the transition suggesting that the infall is accelerating toward the center of the core, consistent with gravitational collapse. Despite the monolithic appearance of the Main core, the presence of red-shifted absorption, the existence of two embedded free-free sources at the center, and the rotational spin-up are consistent with an unstable core undergoing fragmentation with infall and differential rotation due to conservation of angular momentum. Therefore, the most likely explanation for the monolithic morphology is that the large opacity of the dust emission prevents the detection of any inhomogeneity in the core.
Secreted Immunomodulatory Proteins of Staphylococcus aureus Activate Platelets and Induce Platelet Aggregation
2018-03-19

Abstract Staphylococcus aureus can cause bloodstream infections associated with infective endocarditis (IE) and disseminated intravascular coagulopathy (DIC). Both complications involve platelets. In view of an increasing number of antibiotic-resistant strains, new approaches to control systemic S. aureus infection are gaining importance. Using a repertoire of 52 recombinant S. aureus proteins in flow cytometry-based platelet activation and aggregation assays, we identified, in addition to the extracellular adherence protein Eap, three secreted staphylococcal proteins as novel platelet activating proteins. Eap and the chemotaxis inhibitory protein of S. aureus (CHIPS), the formyl peptide receptor-like 1 inhibitory protein (FLIPr) and the major autolysin Atl induced P-selectin expression in washed platelets and platelet-rich plasma. Similarly, AtlA, CHIPS and Eap induced platelet aggregation in whole blood. Fluorescence microscopy illustrated that P-selectin expression is associated with calcium mobilization and re-organization of the platelet actin cytoskeleton. Characterization of the functionally active domains of the major autolysin AtlA and Eap indicates that the amidase domain of Atl and the tandem repeats 3 and 4 of Eap are crucial for platelet activation. These results provide new insights in S. aureus protein interactions with platelets and identify secreted proteins as potential treatment targets in case of antibiotic-resistant S. aureus infection.
Prediction of Glucose Tolerance without an Oral Glucose Tolerance Test
2018-03-19

Machine learning methods yield moderate accuracy in predicting glucose tolerance from a wide set of clinical and laboratory variables. A substitution of OGTT does not currently seem to be feasible. An important constraint could be the limited reproducibility of glucose tolerance status during a subsequent OGTT.
A paleomagnetic record in loess–paleosol sequences since late Pleistocene in the arid Central Asia
2018-03-19

Geomagnetic excursions during Brunhes epoch have been brought to the forefront topic in paleomagnetic study, as they provide key information about Earth's interior dynamics and could serve as another tool for stratigraphic correlation among different lithology. Loess-paleosol sequences provide good archives for decoding geomagnetic excursions. However, the detailed pattern of these excursions was not sufficiently clarified due to pedogenic influence. In this study, paleomagnetic analysis was performed in loess-paleosol sequences on the northern piedmont of the Tianshan Mountains (northwestern China). By radiocarbon and luminance dating, the loess section was chronologically constrained to mainly the last c.130 ka, a period when several distinct geomagnetic excursions were involved. The rock magnetic properties in this loess section are dominated by magnetite and maghemite in a pseudo-single-domain state. The rock magnetic properties and magnetic anisotropy indicate weakly pedogenic influence for magnetic record. The stable component of remanent magnetization derived from thermal demagnetization revealed the presence of two intervals of directional anomalies with corresponding intensity lows in the Brunhes epoch. The age control in the key layers indicates these anomalies are likely associated with the Laschamp and Blake excursions, respectively. In addition, relative paleointensity in the loess section is basically compatible with other regional and global relative paleointensity records and indicates two low-paleointensity zones, possibly corresponding to the Blake and Laschamp excursions, respectively. As a result, this study suggests that the loess section may have the potential to record short-lived excursions, which largely reflect the variation of dipole components in the global archives.
Almahata Sitta MS-MU-011 and MS-MU-012: Formation Conditions of Two Unusual Rocks From the Ureilite Parent Body
2018-03-19

Almahata Sitta meteorites are unique polymict breccia, comprising of many different meteorite groups as individual fragments dominated by ureilite lithologies and are considered to be recovered fragments of the asteroid 2008TC3. Recently, two unusual Almahata Sitta samples (MS-MU-011 and MS-MU-012) have been reported that show close petrogenetic relationships to ureilites. MS-MU-011 is a trachyandesite mainly composed of feldspar (plagioclase and anorthoclase) and pyroxene (pigeonite and augite) having ureilitic oxygen isotopic ratios. MS-MU-012 is the first ureilite example (unbrecciated) containing primary plagioclase crystals. The findings of these two rock types are important to better understand formation conditions of ureilites and the evolution of their parent body(s). In this abstract we discuss formation conditions of these ureilite-related rocks using redox state estimate by Fe valence states of plagioclase and olivine cooling rate calculations.
The Role of Work-Related Factors in the Development of Psychological Distress and Associated Mental Disorders: Differential Views of Human Resource Managers, Occupational Physicians, Primary Care Physicians and Psychotherapists in Germany
2018-03-20

Objectives: This study analyses the perceived relevance of stress-dimensions in work-settings from the differential views of Human Resource Managers (HRM), Occupational Physicians (OP), Primary Care Physicians (PCP) and Psychotherapists (PT) in Germany. Methods: Cross-sectional study design, using a self-report questionnaire. Descriptive measures and explorative bivariate methods were applied for group-comparisons. Results are presented as rankings of perceived importance and as polarity profiles of contrasting views. Results: N = 627 participants completed the questionnaires (HRM: n = 172; OP: n = 133; PCP: n = 136; PT: n = 186). The stress dimensions with the highest mean ratings across all four professions were: ‘social relationships in the work place’ (M = 3.55, SD = 0.62) and ‘superiors ́ leadership style’ (M = 3.54, SD = 0.64). Mean ratings of perceived relevance of stress dimensions differed most between HRM and the three medical professions. Conclusions: The perceived importance of work-related stress-dimensions seems to be higher in the medical disciplines (OP, PCP, PT) than in the group from the management sector (HRM). However, no fundamental disagreement on the role of work-related stress-dimensions seems to hinder e.g., intensified efforts of cooperation across sectors in tackling the “stress-pandemic” and improving the (mental) health of employees.
Identification of compound heterozygous variants in OPTN in an ALS-FTD patient from the CReATe consortium: a case report
2018-03-20

Homozygous loss-of-function mutations in optineurin (OPTN) are a rare cause of amyotrophic lateral sclerosis (ALS), whereas heterozygous loss-of-function mutations have been suggested to increase ALS disease risk. We report a patient with ALS and frontotemporal dementia (FTD) from the Clinical Research in ALS and Related Disorders for Therapeutic Development (CReATe) Consortium carrying compound heterozygous loss-of-function variants in OPTN. Quantitative real-time mRNA expression analyses revealed a 75-80% reduction in OPTN expression in blood in the OPTN carrier as compared to controls, suggesting at least partial nonsense-mediated decay of the mutant transcripts. This case report illustrates the diverse inheritance patterns and variable clinical presentations associated with OPTN mutations, and underscores the importance of complete OPTN gene screening in patients with ALS and related disorders, especially in the context of clinical genetic testing.
Why are some groups physically active and others not? A contrast group analysis in leisure settings
2018-03-20

Our study shows that several social factors determine the physical activity of very active and very inactive groups. In order to promote physical activity, future health initiatives should target these factors of a person's network.
TEXTUAL ISSUES IN BASIL OF CAESAREA'SHOMILIAE IN HEXAEMERON4 AND 5
2018-03-20

This paper proposes a number of improvements to the text of Basil of Caesarea's Homiliae in hexaemeron 4 and 5. The biblical text poses particular problems for the fourth and the fifth homilies. Therefore, the text form of Genesis from these two homilies is discussed first, and then further individual instances from the fourth and the fifth homilies are examined. The passages are presented in the format of a commentary under the assumption that the reader has the GCS edition at hand.
Cyclic Distannene or Bis(stannylene) with a Ferrocenyl Backbone: Synthesis, Structure, and Coordination Chemistry
2018-03-21

1,1'-Dilithioferrocene was reacted with 2 equiv of isopropyl (Ar*) or methyl (Ar') substituted terphenyl tin(II) chloride. Reaction product 1, carrying the bulkier terphenyl substituent Ar*, displays a bis(stannylene) structure in the solid state without formation of a tin-tin bond. Temperature-dependent solution <sup>119</sup>Sn NMR spectroscopy, however, revealed a dynamic interplay between bis(stannylene) (100 °C) and cyclic distannene (-80 °C). In contrast to 1, the less bulky Ar' substituent results in a cyclic distannene 2. On the basis of temperature-dependent <sup>119</sup>Sn NMR spectroscopy the Sn-Sn bond of compound 2 was preserved up to 100 °C. Both compounds were further characterized by solid-state <sup>119</sup>Sn NMR spectroscopy as well as <sup>119</sup>Sn and <sup>57</sup>Fe Mössbauer spectroscopy. 1 reacted as a chelating ligand with nickel and palladium complexes [Ni(cod)<sub>2</sub>] and [Pd(nbe)<sub>3</sub>] (nbe = norbornene). In the resulting coordination compounds the nonstabilized stannylene acts as a donor as well as an acceptor ligand and shows a dynamic switch from donor to acceptor behavior in the monopalladium complex.
Crafting Aboriginal Nations in Taiwan: The Presbyterian Church and the Imagination of the Aboriginal National Subject
2018-03-21

This study argues that since the end of World War II, the Taiwanese Presbyterian Church's practical institutionalised arrangements for evangelisation have had the unintended consequence of creating an imagined multi-layered aboriginal national Subject. The argument is founded upon analysis of three main points. First, aboriginal members' daily practices within the three-level federalist church polity formed in their minds an acquired "schema", a ready-made cognitive structure that could be easily appropriated by them to imagine their own nations in a certain way. Second, when the Church promoted the translation of the Bible and hymns into aboriginal vernaculars for practical evangelising reasons, it unintentionally created tribe-based cultural-linguistic mediums as national languages upon which the contents of aboriginal nations could be elaborated and reproduced. This step further consolidated tribe-based ethnic categorisation and facilitated the reification of aboriginal nations. Third, since aboriginal ministers and elders were institutionally endowed with many strengths in comparison to other aboriginal elites, they came to serve as human activators in formulating and spreading the imagination of the multi-layered aboriginal national Subject.
Tuning of Thiyl/Thiolate Complex Near-Infrared Chromophores of Platinum through Geometrical Constraints
2018-03-21

The chemistry of radical-ligand complexes of the transition metals has developed into a vibrant field of research that spans from fundamental studies on the relationship between the chemical and electronic structures to applications in catalysis and functional materials chemistry. In general, fine-tuning of the relevant properties relies on an increasingly diversifying pool of radical-proligand structures. Surprisingly, the variability of the conformational freedom and the number of distinct bonding modes supported by many radical proligands is limited. This work reports on the angular constraints and relative geometric alignment of metal and ligand orbitals as key parameters that render a series of chemically similar thiyl/thiolate complexes of platinum(II) electronically and spectroscopically distinct. The use of conformational flexible thiophenols as primary ligand scaffolds is essential to establishing a defined radical-ligand [(<sup>arene</sup>S)<sub>2</sub>Pt<sup>II</sup>]<sup>•+</sup> core whose electronic structure is modulated by a series of auxiliary coligands at platinum.
Aversive conditioning in oddball paradigm modulates multisensory integration, attention and emotional processing
2018-03-21

Abstract The nature of cortical plasticity in the course of learning is one of the most intriguing questions of the modern cognitive neuroscience. Aversive conditioning is a type of associative learning produced by continuous pairing of neutral and aversive stimuli. Aversive conditioning and electroencephalography together provide a good framework for expanding our knowledge about fast learning-related cortical changes. In our experiment we tested a novel paradigm to study associative learning where aversive conditioning was combined with passive oddball. We employed conditioned auditory neutral stimuli and unconditioned aversive electrical shocks and used time-frequency, connectivity and event-related potentials (ERP) analyses to explore their interaction. First, we observed changes in the cortical activity in the form of conditioning-induced multisensory integration. The integration manifested itself in (1) desynchronization of lower beta activity in the contralateral to expected electrical shocks hemisphere and (2) enhanced functional connectivity between auditory and somatosensory cortex in the gamma frequency band. Second, we found a larger amplitude of P3a and the late posterior positivity (LPP) components of ERP to conditioned stimuli, which may be related to increased attentional and emotional significance of these stimuli. Our results reproduced and extended previous findings about multisensory integration in classical conditioning and demonstrated the improved discriminability of ERP responses through incorporation of the oddball paradigm in associative learning.
The influence of subducting slab advance and erosion on overriding plate deformation in orogen syntaxes
2018-03-21

Abstract. Focused, rapid exhumation of rocks is observed at some plate corners, but the driving mechanisms remain poorly understood and contested. In this study, we use a fully coupled thermo-mechanical numerical model to investigate the effect of slab advance and different erosion scenarios on overriding plate deformation. The subducting slab in the model is curved in 3D, analogous to the indenter geometry observed in seismic studies. We find that the amount of slab advance dramatically changes the orientation of major shear zones in the upper plate and the location of rock uplift zones. Shear along the subduction interface facilitates the formation of a basal detachment situated above the indenter, causing localized rock uplift there. Switching from flat (total erosion) to more realistic fluvial erosion leads to variation of rock uplift on the catchment-scale. Here, deepest exhumation again occurred above the indenter apex. We conclude that the change in orientation and dip angle set by the indenter geometry facilitates creation of localized uplift regions as long as subduction of the down-going plate is active. Tectonic uplift is modulated on even smaller scales by lithostatic pressure from the overburden of the growing orogen, and highest rock uplift can occur when a strong tectonic uplift field spatially coincides with large erosion potential. This implies that both the geometry of the subducting plate and the geomorphic and climatic conditions are important for the creation of focused, rapid exhumation.
Gene expression profiling reveals a close relationship between follicular lymphoma grade 3A and 3B, but distinct profiles of follicular lymphoma grade 1 and 2
2018-03-22

A linear progression model of follicular lymphomas (FL) FL1, FL2 and FL3A has been favored, since FL3A often co-exist with an FL1/2 component. FL3B, in contrast, is thought to be more closely related to diffuse large B-cell lymphoma (DLBCL), and both are often simultaneously present in one tumor (DLBCL/FL3B). To obtain more detailed insights into follicular lymphoma progression, a comprehensive analysis of a well-defined set of FL1/2 (n=22), FL3A (n=16), FL3B (n=6), DLBCL/FL3B (n=9), and germinal center B-cell-type diffuse large B-cell lymphoma (n=45) was undertaken using gene expression profiling, immunohistochemical stainings and genetic analyses by fluorescence <i>in situ</i> hybridization. While immunohistochemical (CD10, IRF4/MUM1, Ki67, BCL2, BCL6) and genetic profiles (translocations of BCL2, BCL6 and MYC) delineate FL1-3A from FL3B and DLBCL/FL3B, significant differences were observed between FL1/2 and FL3A upon gene expression profiling. Interestingly, FL3B turned out to be closely related to FL3A, not categorizing within a separate gene expression cluster, and both FL3A and FL3B showed overlapping profiles in between FL1/2 and diffuse large B-cell lymphoma. Finally, based upon their gene expression pattern, DLBCL/FL3B represent a composite form of FL3B and DLBCL, with the majority of samples more closely resembling the latter. The fact that gene expression profiling clearly separated FL1/2 from both FL3A and FL3B suggests a closer biological relationship between the latter. This notion, however, is in contrast to immunohistochemical and genetic profiles of the different histological FL subtypes that point to a closer relationship between FL1/2 and FL3A, and separates them from FL3B.
Ancient Fennoscandian genomes reveal origin and spread of Siberian ancestry in Europe
2018-03-22

Abstract European history has been shaped by migrations of people, and their subsequent admixture. Recently, evidence from ancient DNA has brought new insights into migration events that could be linked to the advent of agriculture, and possibly to the spread of Indo-European languages. However, little is known so far about the ancient population history of north-eastern Europe, in particular about populations speaking Uralic languages, such as Finns and Saami. Here we analyse ancient genomic data from 11 individuals from Finland and Northwest Russia. We show that the specific genetic makeup of northern Europe traces back to migrations from Siberia that began at least 3,500 years ago. This ancestry was subsequently admixed into many modern populations in the region, in particular populations speaking Uralic languages today. In addition, we show that ancestors of modern Saami inhabited a larger territory during the Iron Age than today, which adds to historical and linguistic evidence for the population history of Finland.
Chronological and Isotopic data support a revision for the timing of cave bear extinction in Mediterranean Europe
2018-03-22

The Cave Bear, <i>Ursus spelaeus</i> (<i>sensu lato</i>), was one of many megafaunal species that became extinct during the Late Pleistocene in Europe. With new data we revisit the debate about the extinction and paleoecology of this species by presenting new chronometric, isotopic and taphonomic evidence from two Palaeolithic cave bear sites in northeastern Italy: Paina Cave and Trene Cave. Two direct radiocarbon dates on well-preserved collagen have yielded ages around 24,200–23,500 cal yr BP, which make them the latest known representatives of the species in Europe. The carbon (<i>δ</i><sup>13</sup>C) and nitrogen (<i>δ</i><sup>15</sup>N) isotopic values of bone collagen exhibit values similar to those of older cave bears from Swabian Jura and France, suggesting that the feedings preferences of cave bears remained unchanged until the disappearance of this species in Europe. Several bear remains preserved traces of human modification such as cut marks, which enables a reconstruction of the main steps of fur recovery and the butchering process. The broad range of plant types available and the favorable location of Berici Hills may have played an important role in the range expansion of cave bears and their interaction with the Paleolithic hunters settled the same area.