PD24-01 PROOF-OF-CONCEPT FOR DATA FUSION OF URETHRAL PRESSURE DATA AND MRI
2015-03-31

You have accessJournal of UrologyUrodynamics/Incontinence/Female Urology: Incontinence: Evaluation (Urodynamic Testing)1 Apr 2015PD24-01 PROOF-OF-CONCEPT FOR DATA FUSION OF URETHRAL PRESSURE DATA AND MRI Mario Klünder, Susanne Will, Karl-Dietrich Sievert, Bastian Amend, Ronny Feuer, Oliver Sawodny, Ulrich Kramer, Arnulf Stenzl, and Michael Ederer Mario KlünderMario Klünder More articles by this author , Susanne WillSusanne Will More articles by this author , Karl-Dietrich SievertKarl-Dietrich Sievert More articles by this author , Bastian AmendBastian Amend More articles by this author , Ronny FeuerRonny Feuer More articles by this author , Oliver SawodnyOliver Sawodny More articles by this author , Ulrich KramerUlrich Kramer More articles by this author , Arnulf StenzlArnulf Stenzl More articles by this author , and Michael EdererMichael Ederer More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.02.1456AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Urethral Pressure Profile (UPP) is the instrument to verify stress urinary incontinence (SUI) whereby a catheter with pressure sensing capability is retracted through the urethra to obtain the UPP. Using a novel microtip catheter and a specifically-developed signal reconstruction algorithm, a detailed map of the spatial pressure distribution inside the urethra can be illustrated. Little is known about the effect of anatomical or pathological conditions in the sphincter structure, however, MRI provides data of the anatomy and surrounding tissue without being able to quantify its pressure effects. Data fusion of MRI and UPP can provide the physician with a better understanding of the conditions in and around the urethra to improve the diagnosis and select the optimal treatment. METHODS A microtip catheter prototype was used with a total of 9 pressure sensors and an acceleration sensor to determine the orientation of the catheter during the measurement on a sedated female minipig. The UPP data was processed through a special signal reconstruction algorithm to obtain the spatial pressure distribution inside the urethra. In another female minipig, which underwent MRI in a 3T MR scanner, slices were placed orthogonally with the urethra. The enlarged images were sharpened and colored for better contrast. Finally, fusion of both datasets was carried out using Matlab®. RESULTS MRI images were stacked at slice thickness intervals. The bladder neck was identified and aligned in both MRI and UPP data. Through the catheter's acceleration sensor, UPP data was precisely oriented, (e.g. the dorsal side in UPP data aligned with the dorsal side in MRI). The 3D-plot can be freely rotated so that the physician can attain a detailed understanding of both the anatomy around the urethra (MRI) and the corresponding 3D-UPP. CONCLUSIONS MRI images were stacked at slice thickness intervals. The bladder neck was identified and aligned in both MRI and UPP data. Through the catheter's acceleration sensor, UPP data was precisely oriented, (e.g. the dorsal side in UPP data aligned with the dorsal side in MRI). The 3D-plot can be freely rotated so that the physician can attain a detailed understanding of both the anatomy around the urethra (MRI) and the corresponding pressure distribution inside (UPP). © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 4SApril 2015Page: e486 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Mario Klünder More articles by this author Susanne Will More articles by this author Karl-Dietrich Sievert More articles by this author Bastian Amend More articles by this author Ronny Feuer More articles by this author Oliver Sawodny More articles by this author Ulrich Kramer More articles by this author Arnulf Stenzl More articles by this author Michael Ederer More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...