julilili42/papers huggingface dataset:
Spectroscopic analyses of the blue hook stars in NGC 2808: A more stringent test of the late hot flasher scenario
2004-02-01

Recent UV observations of the globular cluster NGC 2808 (Brown et al. 2001) show a significant population of hot stars fainter than the zero-age horizontal branch ("blue hook" stars), which cannot be explained by canonical stellar evolution. Their results suggest that stars which experience unusually large mass loss on the red giant branch and which subsequently undergo the helium core flash while descending the white dwarf cooling curve could populate this region. Theory predicts that these "late hot flashers" should show higher temperatures than the hottest canonical horizontal branch stars and should have helium- and carbon-rich atmospheres. As a test of this late hot flasher scenario, we have obtained and analysed medium resolution spectra of a sample of blue hook stars in NGC 2808 to derive their atmospheric parameters. Using the same procedures, we have also re-analyzed our earlier spectra of the blue hook stars in omega Cen (Moehler et al. 2002) for comparison with the present results for NGC 2808. The blue hook stars in these two clusters are both hotter (T-eff greater than or equal to 35 000 K) and more helium-rich than canonical extreme horizontal branch stars in agreement with the late hot flasher scenario. Moreover, we find indications for carbon enhancement in the three most helium-enriched stars in NGC 2808. However, the blue hook stars still show some hydrogen in their atmospheres, perhaps indicating that some residual hydrogen survives a late hot flash and then later diffuses to the surface during the horizontal branch phase. We note that the presence of blue hook stars apparently depends mostly on the total mass of the globular cluster and not so much on its horizontal branch morphology.
Induction of Adipophilin-Specific Cytotoxic T Lymphocytes Using a Novel HLA-A2-Binding Peptide That Mediates Tumor Cell Lysis
2004-02-01

Abstract Identification of tumor-associated antigens and advances in tumor immunology resulted in the development of vaccination strategies to treat patients with malignant diseases. Using a novel approach that combines DNA chip analysis of tumor samples with isolation of peptides on the surface of tumor cells, a HLA-A*0201-binding peptide derived from the adipophilin protein was identified. Adipophilin is involved in lipid storage and was thought to be expressed only in adipocytes, but it can be found in other cell types such as macrophages or tumor cells. In the present study, we analyzed the possible use of this peptide as a T-cell epitope presented by malignant cells. To accomplish this, we induced CTL responses using this HLA-A*0201-binding peptide. The in vitro-induced CTLs efficiently lysed cells pulsed with the adipophilin peptide and HLA-matched tumor cell lines in an antigen-specific and HLA-restricted manner. Finally, the induced CTLs recognized autologous dendritic cells (DCs) pulsed with the antigenic peptide or transfected with tumor RNA purified from an adipophilin-expressing tumor cell line. To further analyze the possible use of this peptide in immunotherapies of human malignancies, we induced adipophilin-specific CTLs using peripheral blood mononuclear cells and DCs from HLA-A*0201-positive patients with chronic lymphatic leukemia and plasma cell leukemia. The in vitro-generated CTLs recognized autologous chronic lymphatic leukemia cells and malignant plasma cells, whereas they spared nonmalignant resting or activated B and T lymphocytes, monocytes, or DCs. Our results demonstrate that this peptide might represent an interesting candidate for the development of cancer vaccines designed to target adipophilin-derived epitopes in a wide range of malignancies.
Cystinuria-specific rBAT(R365W) mutation reveals two translocation pathways in the amino acid transporter rBAT-b0,+AT
2004-02-01

Apical reabsorption of dibasic amino acids and cystine in kidney is mediated by the heteromeric amino acid antiporter rBAT/b0,+AT (system b0,+). Mutations in rBAT cause cystinuria type A, whereas mutations in b0,+AT cause cystinuria type B. b0,+AT is the catalytic subunit, whereas it is believed that rBAT helps the routing of the rBAT/b0,+AT heterodimeric complex to the plasma membrane. In the present study, we have functionally characterized the cystinuria-specific R365W (Arg365→Trp) mutation of human rBAT, which in addition to a trafficking defect, alters functional properties of the b0,+ transporter. In oocytes, where human rBAT interacts with the endogenous b0,+AT subunit to form an active transporter, the rBAT(R365W) mutation caused a defect of arginine efflux without altering arginine influx or apparent affinities for intracellular or extracellular arginine. Transport of lysine or leucine remained unaffected. In HeLa cells, functional expression of rBAT(R365W)/b0,+AT was observed only at the permissive temperature of 33 °C. Under these conditions, the mutated transporter showed 50% reduction of arginine influx and a similar decreased accumulation of dibasic amino acids. Efflux of arginine through the rBAT(R365W)/b0,+AT holotransporter was completely abolished. This supports a two-translocation-pathway model for antiporter b0,+, in which the efflux pathway in the rBAT(R365W)/b0,+AT holotransporter is defective for arginine translocation or dissociation. This is the first direct evidence that mutations in rBAT may modify transport properties of system b0,+.
HIV transmission during paediatric health care in sub-Saharan Africa--risks and evidence.
2004-02-01

Health care systems in sub-Saharan Africa are challenged not only to improve care for the increasing number of HIV-infected children, but also to prevent transmission of HIV to other children and health care workers through contaminated medical procedures and needlestick accidents. HIV-infected children aged to 1 year typically have high viral loads, making them dangerous reservoirs for iatrogenic transmission. Most vertically infected children experience HIV-related symptoms early, though many survive beyond 5 years. This leads to high HIV prevalence among inpatient and outpatient children. In nine African studies, HIV prevalence in inpatient children ranged from 8.2% to 63%, roughly 1-3 times the prevalence in antenatal women. Investigations of large iatrogenic outbreaks in Russia, Romania, and Libya demonstrate efficient HIV transmission through paediatric health care. Unexplained HIV infections in African children are not rare-studies published through 2003 have recorded more than 300 HIV-infected children with HIV-negative mothers. In addition, several studies have reported much higher HIV prevalence in children 5-14 years old than could be expected from mother-to-child transmission alone. Research is required to determine the extent of iatrogenic HIV infection among African children as well as to identify high-risk procedures and settings. Such research can motivate and direct prevention efforts.
Constructional Morphology of Pelagic Crinoids
2004-02-01

Other| February 01, 2004 Constructional Morphology of Pelagic Crinoids ADOLF SEILACHER; ADOLF SEILACHER 1Universität Tübingen, Sigwartstrasse 10, 72076 Tübingen, Germany, and Geology & Geophysics Department, Yale University, P.O. Box 208109, New Haven, CT, 06520-8109, geodolf@tuebingen.netsurf.de Search for other works by this author on: GSW Google Scholar ROLF B. HAUFF ROLF B. HAUFF 2Urwelt-Museum Hauff, Aichelberger Strasse 90, 73271 Holzmaden/Teck, Germany Search for other works by this author on: GSW Google Scholar Author and Article Information ADOLF SEILACHER 1Universität Tübingen, Sigwartstrasse 10, 72076 Tübingen, Germany, and Geology & Geophysics Department, Yale University, P.O. Box 208109, New Haven, CT, 06520-8109, geodolf@tuebingen.netsurf.de ROLF B. HAUFF 2Urwelt-Museum Hauff, Aichelberger Strasse 90, 73271 Holzmaden/Teck, Germany Publisher: SEPM Society for Sedimentary Geology Accepted: 15 Sep 2003 First Online: 03 Mar 2017 Online ISSN: 1938-5323 Print ISSN: 0883-1351 Society for Sedimentary Geology PALAIOS (2004) 19 (1): 3–16. https://doi.org/10.1669/0883-1351(2004)019<0003:CMOPC>2.0.CO;2 Article history Accepted: 15 Sep 2003 First Online: 03 Mar 2017 Cite View This Citation Add to Citation Manager Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Get Permissions Search Site Citation ADOLF SEILACHER, ROLF B. HAUFF; Constructional Morphology of Pelagic Crinoids. PALAIOS 2004;; 19 (1): 3–16. doi: https://doi.org/10.1669/0883-1351(2004)019<0003:CMOPC>2.0.CO;2 Download citation file: Ris (Zotero) Refmanager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentBy SocietyPALAIOS Search Advanced Search Abstract While all modern crinoids are benthic filter feeders, some fossil species found in low-oxygen Konservat-Lagerstätten probably were pelagic. Pseudoplanktonic forms were mostly attached to driftwood (Seirocrinus, Traumatocrinus, Melocrinus); they had long, rope-like stems and enlarged, permanently splayed filter fans, as required for a passive tow-net function. However, the short and heavily cirrated stem of another driftwood-dweller (Pentacrinites) suggests active filter feeding. If the buoyant lobolith of Scyphocrinites acted as a swim bladder, this crinoid, by the same tow-net principle, could have made use of velocity gradients near a boundary layer. Paradigms are different for stemless forms, whether they floated passively over the bottom (Uintacrinus) or filtrated actively in the water column (Roveacrinids and Saccocoma). Some of the proposed models could not function with the muscular and ligamentary system of modern forms. Nevertheless, they represent distinctive peaks in the adaptive landscape that can be tested using taphonomic, morphological, and evolutionary evidence. You do not have access to this content, please speak to your institutional administrator if you feel you should have access.
LurcherMice Exhibit Potentiation of GABAA-Receptor–Mediated Conductance in Cerebellar Nuclei Neurons in Close Temporal Relationship to Purkinje Cell Death
2004-02-01

In heterozygous Lurcher mice ( Lc/+), the Purkinje cells (PCs) degenerate almost totally during postnatal development. On the other hand, their projection target, the deep cerebellar nuclei (DCN), shows few signs of degeneration and seems to play an important role in maintaining a residual cerebellar function in Lc/+. We asked whether the DCN in Lc/+ develop cellular adaptations allowing them to cope with the loss of GABAergic PC input. Using whole-cell patch-clamp recordings, we measured inhibitory postsynaptic currents from DCN of Lc/+ and wild-type mice (WT). In experiments on phenotypically striking Lc/+ studied well after the onset of the PC degeneration, we found enlarged average synaptic conductances ( g syn ) compared with WT. We next investigated postnatal mice before and after the onset of PC death. In younger animals ≤ postnatal day (p) 13, no difference was found in g syn between the two groups. At p14, g syn in Lc/+ showed an increase, while those in WT stayed on the level found in younger animals. A peak-scaled nonstationary fluctuation analysis suggests that an increase in the average number of channels open at peak is the basis for the change in g syn . The changes in g syn , suitable to increase the efficacy of GABAergic transmission, occur in close temporal relationship to PC death and, thus, may reflect a functional adaptation to the loss of the DCN's main GABAergic afferents.
DESCRIPTION OF THE SUPERDEFORMED BAND OF 36Ar WITH THE GOGNY FORCE
2004-02-01

The superdeformed band of 36 Ar is studied with the Gogny force D1S and the angular momentum projected generator coordinate method for the quadrupole moment. The band head excitation energy, moments of inertia, B(E2) transition probabilities and stability against quadrupole fluctuations at low spin are studied. The Self Consistent Cranking method is also used to describe the superdeformed rotational band. In addition, properties of some normal deformed states are discussed.
Release of S(+) enantiomers in breath samples after anaesthesia with isoflurane racemate
2004-02-01

During the first days after application of isoflurane racemate, the percentage of S(+) enantiomers are higher in breath and blood samples of patients. We suggest that resorption and/or redistribution of enantiomers are responsible for the different kinetics of isoflurane enantiomers.
Typification of the fossil conifer Pseudovoltzia liebeana (Geinitz) Florin
2004-02-01

Abstract A neotype for the fossil conifer Pseudovoltzia liebeana (Geinitz) Florin is designated. It has been chosen from the material figured by Geinitz in 1880, which is stored at the Sächsische Naturhistorische Sammlungen Dresden/Museum für Mineralogie und Geologie.
Synthese und Struktur der Nitridokomplexe (Ph3Sb)2Cl3Os≡N-RhCl(COD), (Me2PhP)2(PhCN)Cl2Re≡N-RhCl2(C5Me5), [(Me2PhP)3(PhCN)ClRe≡N-OsCl2(CO)3][OsCl3(CO)3] und [(Me2PhP)3(PhCN)ClRe≡N-ReCl4-N≡ReCl(NCPh)(PMe2Ph)3][OsCl4(CO)2] / Synthesis and Structure of the Nitrido Complexes (Ph3Sb)2Cl3Os≡N-RhCl(COD), (Me2PhP)2(PhCN)Cl2Re≡N-RhCl2(C5Me5), [(Me2PhP)3(PhCN)ClRe≡N-OsCl2(CO)3][OsCl3(CO)3], and [(Me2PhP)3(PhCN)ClRe≡N-ReCl4-N≡ReCl(NCPh)(PMe2Ph)3][OsCl4(CO)2]
2004-02-01

The reaction of (Ph 3 Sb) 2 Cl 3 OsN with [Rh(μ-Cl)(COD)] 2 in benzonitrile yields the heteronuclear nitrido complex (Ph 3 Sb) 2 Cl 3 Os≡N-RhCl(COD) (1). It crystallizes as dark brown blocks in the triclinic space group P1 with a = 1080.09(5), b = 1173.15(5), c = 1702.28(9) pm, α = 101.214(4), β = 92.923(8), γ = 92.836(5)֯, and Z = 2. The complex fragment RhCl(COD) is coordinated to the osmium nitrido complex via a linear nitrido bridge Os≡N-Rh, with a bond angle Os-N-Rh = 175.3(5)° and distances Os-N = 168.6(6) and Rh-N = 184.6(6) pm. The heteronuclear complexes (Me 2 PhP) 2 (PhCN)Cl 2 Re≡N-RhCl 2 (C 5 Me 5 ) (2) and [(Me 2 PhP) 3 (PhCN)ClRe≡NOsCl 2 ( CO) 3 ][OsCl 3 (CO) 3 ] (3) are obtained by the reaction of (Me 2 PhP) 3 Cl 2 ReN with [RhCl(μ- Cl)(C 5 Me 5 )] 2 and [OsCl(μ-Cl)(CO) 3 ] 2 , respectively, in benzonitrile. 2 forms orange red crystals with the composition 2・C 6 H 5 CN in the monoclinic space group P2 1 /c and a =910.23(7), b =1255.4(1), c = 3761.5(3) pm, β = 95.617(9)° and Z = 4. The nitrido bridge Re≡N-Rh to the complex fragment [RhCl 2 (C 5 Me 5 )] has a bond angle Re-N-Rh of 171.9(3)° and distances Re-N = 169.4(5) and Rh-N = 201.9(5) pm. 3 forms yellow orange plates with the monoclinic space group P2 1 /c and a = 1113.74(5), b = 2038.5(2), c = 2130.1(1) pm, β = 90.298(6)° and Z = 4. The nitrido bridge within the complex cation [(Me 2 PhP) 3 (PhCN)ClRe≡N-OsCl 2 (CO) 3 ] + is characterized by a bond angle Re-N-Os of 167.7(4)° and distances Re-N = 169.5(8) and Os-N = 206.1(8) pm. The ligands of the octahedral anion [OsCl 3 (CO) 3 ] − are in a facial arrangement. The synthesis of 3 yields [{(Me 2 PhP) 3 (PhCN)ClRe≡N} 2 ReCl 4 ][OsCl 4 (CO) 2 ] (4) as a byproduct. It crystallizes as red brown blocks with the composition 4·CH 2 Cl 2 in the space group P1 and a = 1444.2(1), b = 1536.3(1), c = 2150.5(2) pm, α =87.41(1), β =88.54(1), γ =62.453(8)° and Z =2. In the two symmetry independent, centrosymmetric cations [(Me 2 PhP) 3 (PhCN)ClRe≡N-ReCl 4 -N≡ReCl(NCPh)(PMe 2 Ph) 3 ] 2+ of 4 two nitrido complexes [(Me 2 PhP) 3 (PhCN)ClReN] + coordinate with their terminal nitrido ligands a central, square planar ReCl 4 unit. The resulting nitrido bridges with bond angles Re(1)-N(1)- Re(2) = 167.0(4)° and Re(3)-N(2)-Re(4) = 168.9(4)°, respectively, exhibit distances Re(1)-N(1) = 172.4(7) and Re(2)-N(1) = 197.1(7) or Re(3)-N(2) = 171.4(6) and Re(4)-N(2) = 197.1(6) pm. The two carbonyl ligands of the anion [OsCl 4 (CO) 2 ] 2− are in cis position.
Topography and tribological behaviour of lubricating greases – an experimental study
2004-02-01

Greases are non‐Newtonian fluids with a special rheological and tribological behaviour. They have a wide range of applications, for example, ball bearings and gears. This paper reports a study of the reaction of model greases in a tribological contact. The influence of the grease topography has been measured in several tests and the tribological process is modelled. All investigations were done from an energy point of view.
A New Gene-finding Tool
2004-02-01

How can a large number of different phenotypes be generated by a limited number of genotypes? Promiscuity between different, structurally related and/or unrelated proteins seems to provide a plausible explanation to this pertinent question. Strategies able to predict such functional interrelations between different proteins are important to restrict the number of putative candidate proteins, which can then be subjected to time-consuming functional tests. Here we describe the use of the operon structure of the nematode genome to identify partner proteins in human cells. In this work we focus on ion channels proteins, which build an interface between the cell and the outside world and are responsible for a growing number of diseases in humans. However, the proposed strategy for the partner protein quest is not restricted to this scientific area but can be adopted in virtually every field of human biology where protein-protein interactions are assumed.
From Cell Death to Neuronal Regeneration: Building a New Brain after Traumatic Brain Injury
2004-02-01

From Cell Death to Neuronal Regeneration: Building a New Brain after Traumatic Brain Injury (J Neuropathol Exp Neurol 2003;62:801–11) Recently, Royo et al (1) nicely reviewed different approaches that may improve functional neurological outcome after traumatic brain injury; these ranged from inhibition of cell death, cell replacement strategies and stimulation of neurogenesis to blockade of axon growth inhibition and/or its operated intra-axonal signaling pathways. As outlined, axonal growth inhibition in the central ...
Zur Reaktion von 2,3-Dihydro-1,3-diisopropy1-4,5-imidazol-2-yliden mit Bromderivaten der Meldrumsäure [1, 2] / On the Reaction of 2,3-Dihydro-1,3-diisopropy1-4,5-dimethylimidazol-2-ylidene with Bromine Derivatives of Meldrum’s Acid [1, 2]
2004-02-01

The Imidazolium salts [ImH][MelBr] (7) and [ImBr][MelBr] (8) have been obtained from the carbene Im (5) and the Meldrum’s acid derivatives MelHBr (3) and MelBr 2 (4). The crystal structure analyses of 7 and 8 reveal the presence of ion pairs linked by short OH (7: 2.163 Å ) and OBr (8: 2.872 Å ) contacts.
Current accounts dynamics in OECD and EU acceding countries - an intertemporal approach
2004-02-01

The paper extends the standard intertemporal model of the current account to include two important stylised facts: (1) the persistence of current account positions and (2) the relevance of the fiscal balance. Specifically, the paper derives a closed form solution for consumption in the presence of habit persistence and liquidity constraints, which allows us to obtain a dynamic model for the current account where fiscal deficits have an effect. The model is estimated for a panel of 33 countries, including the ten EU acceding countries and structural current account positions are derived. A parsimonious specification including relative income, relative investment and the fiscal balance explains well past current account developments. A key finding of the paper is that, from an intertemporal perspective, current accounts in most acceding countries are currently broadly in line with their structural current account positions. JEL Classification: F32, F41
Stannaborate Chemistry: Nucleophilic Substitution at the Cluster Sphere
2004-02-01

Abstract Nucleophilic substitution at (γ‐chloropropyl)stanna‐ closo dodecaborate [Cl(CH 2 ) 3 SnB 11 H 11 ] − with RLi [R = Ph, Me 2 NC 6 H 4 , ferrocenyl (Fc)] and RMgBr (R = vinyl, benzyl) affords the substitution products containing the anion [RSnB 11 H 11 ] − . The reaction products have been characterized by elemental analysis, NMR spectroscopy and in the cases where R = Ph, Me 2 NC 6 H 4 , Fc and vinyl by X‐ray structure analysis. (© Wiley‐VCH Verlag GmbH &amp; Co. KGaA, 69451 Weinheim, Germany, 2004)
ON THE STABILITY OF PROJECTION AFTER VARIATION SOLUTIONS
2004-02-01

We have performed angular momentum projection with double-constrained Hartree-Fock-Bogoliubov wave functions with the Gogny interaction for the 32 Mg . We show that the more relevant degree of freedom is the quadrupole deformation. Minima of the ground state obtained in single-constrained calculations with this operator are hardly modified in double-constrained calculations insuring thereby the stability of the solution.
On Local Embedding Properties of Injectors of Finite Soluble Groups
2004-02-01

Abstract In the present paper we consider Fitting classes of finite soluble groups which locally satisfy additional conditions related to the behaviour of their injectors. More precisely, we study Fitting classes 1 ≠⊆such that an-injector of G is, respectively, a normal, (sub)modular, normally embedded, system permutable subgroup of G for all G ∈. Locally normal Fitting classes were studied before by various authors. Here we prove that some important results—already known for normality—are valid for all of the above mentioned embedding properties. For instance, all these embedding properties behave nicely with respect to the Lockett section. Further, for all of these properties the class of all finite soluble groups G such that an x-injector of G has the corresponding embedding property is not closed under forming normal products, and thus can fail to be a Fitting class.
German Register Data for Regression Estimation in Survey Sampling – A Study on the German Microcensus Respecting for Data Protection / Stichproben-Regressionsschätzungen im deutschen Mikrozensus mit Registerdaten unter Berücksichtigung des Datenschutzes
2004-02-01

Summary Modern survey sampling methods generally deal with improving estimators with respect to available prior information. An increasingly important source of prior information is data from registers. In some countries, e.g. Canada, The Netherlands, and the Scandinavian countries, personal identification numbers in registers generally make it possible to improve estimation processes mainly due to the exact match of units between register and estimation variable. In many other countries, this exact matching of information is not possible, e.g. for legal reasons. In the German Microcensus, however, the variable unemployed refers to the register data of the Bundesanstalt fur Arbeit in Nuremberg which are not permitted to be matched to each other for legal reasons. This article deals with an improvement of estimators with respect to available auxiliary information within the survey to enable an appropriate use of aggregated register information. A Monte Carlo simulation study will allow for the comparison of the estimators with different information or matching levels. This will be achieved in a practical environment using the data of the German Microcensus which is a 1 % survey sample of the German population. The given example yields recommendations on applying the methodology to similar cases that are influenced by data protection in order to allow for improved estimates in practice.
Conformal Infinity
2004-02-02

The notion of conformal infinity has a long history within the research in Einstein's theory of gravity. Today, "conformal infinity" is related to almost all other branches of research in general relativity, from quantisation procedures to abstract mathematical issues to numerical applications. This review article attempts to show how this concept gradually and inevitably evolved from physical issues, namely the need to understand gravitational radiation and isolated systems within the theory of gravitation, and how it lends itself very naturally to the solution of radiation problems in numerical relativity. The fundamental concept of null-infinity is introduced. Friedrich's regular conformal field equations are presented and various initial value problems for them are discussed. Finally, it is shown that the conformal field equations provide a very powerful method within numerical relativity to study global problems such as gravitational wave propagation and detection.