I have been looking for a good wide toe box shoe for years.  My toes naturally spread out to the point where my wife says I could fit another toe in between the ones I have.  I had researched different ways to lace up shoes to make them feel wider and it worked for a while until my foot would begin to blow out the sides of the shoes.  now insert the Altra One2.  This is the most comfortable running shoe I have ever worn!!!  I have had Asics, Nike, Addidas, Zoot, etc.  This one takes the win easily.  I was previously trading off running in Nike Free 3.0 and the Zoot Ultra Kiawe Race.  I was getting ready to start a marathon training plan for this season and decided I needed a new pair of shoes.  I bought these based on all the other reviews stating how wide the toe box is and the fact they are zero drop!  First pair i bought was a size 10 as that is what I wore in the Nike Free and Zoot Kiawe Race.  The Altras were a little too small, returned for a 10.5.  PERFECT FIT!  I have done multiple long runs in these shoes including speed and tempo work.  Average weekly miles in these shoes is about 30 miles.  They have been great so far!  I will definitely buy another pair of Altras when these give out.