I was really excited to order the new Kayano 22. I had worn out my Kayano 21 from day to day use, gym use, and lots of running.<br /><br />Looks: The seamless design will have to grow on me, it does not look as aggressive as the prior models.<br /><br />Comfort: These have gotten too comfortable. They almost feel like grandpa walking shoes that you can wear all day long.<br /><br />Feel: These shoes feel more flat footed than the previous Kayano's. There might be some mixed emotions on this, not as aggressive on the arch but in turn it seems that the flat design has brought in the comfort.<br /><br />Running: I have done about 20 miles running so far on these shoes. Verdict... great!!<br /><br />Size: I usually buy Kayano's about 1/2 size larger than my regular shoes. For me, the fit was great and did not appear much different from the Kayano 21.<br /><br />Gym Use: squats and deadlifts seem more stable with the flat shoe design.<br /><br />So far I am really enjoying me new shoes!!!