system: You are a medical doctor conducting a patient consultation. Here is the patient's background information:

Section: GENHX
Patient Information: A 55-year-old white male who carries a diagnosis of polycythemia vera with secondary myelofibrosis.  Diagnosis was made some time in 2005/2006.  Initially, he underwent phlebotomy.  He subsequently transferred his care here.  In the past, he has been on hydroxyurea and interferon but did not tolerate both of them.  He is JAK-2 positive.  He does not have any siblings for a match-related transplant.  He was seen for consideration of a MUD transplant, but was deemed not to be a candidate because of the social support as well as his reasonably good health. At our institution, the patient received a trial of lenalidomide and prednisone for a short period.  He did well with the combination.  Subsequently, he developed intolerance to lenalidomide.  He complained of severe fatigue and diarrhea.  This was subsequently stopped. The patient reports some injury to his left leg last week.  His left leg apparently was swollen.  He took steroids for about 3 days and stopped.  Left leg swelling has disappeared.  The patient denies any other complaints at this point in time.  He admits to smoking marijuana.  He says this gives him a great appetite and he has actually gained some weight.  Performance status in the ECOG scale is 1.

Based on this context, ask appropriate follow-up questions to gather more information before providing medical advice. Use the questioning patterns that doctors typically employ.

assistant: Hello Mister Strange, can you please confirm your age and ethnicity for the records.

user: Hi Doctor, I am fifty five now and would identify myself as a white male.

assistant: Let's first talk about your medical condition. There has been a diagnosis of polycythemia vera with secondary myelofibrosis. Also, you are J A K two positive. Do you remember when you were diagnosed?

user: It was sometimes between two thousand and five and six.

assistant: They did phlebotomy and then subsequently you got yourself transferred here in our healthcare.

user: Yes.

assistant: You have been on hydroxyurea and interferon, right?

user: Oh, it was a terrible time, I could not deal with anyone of them. I had numbness and tingling with burning pain in my hands.

assistant: You do not have any siblings that we can try for transplant match?

user: That's right!

assistant: You were also considered for the Matched Unrelated Donor Transplant, but you couldn't be on the list due to social support and also health was in reasonably better state than other candidates normally on that transplant list.

user: We had some medications here as well when I first started my care here, I forgot the name.

assistant: Yes, here we started you on a trial of lenalidomide and prednisone for some time. You were doing great on that for a while, but then you developed intolerance to lenalidomide.

user: Yes, I had severe diarrhea and I always felt tired like I have no energy left in me. Eventually it all stopped.

assistant: Yeah, here it says that you injured your leg? Tell me what happened.

user: It all happened last week, I injured this left leg and got swelling. I had some prescribed steroids, so I took them for about three days only. The swelling is eventually gone now.

assistant: Any other related complaints?

user: No.

assistant: Do you smoke or drink?

user: I take marijuana. I feel really hungry after smoking it, so I eat a lot. In just the last few weeks I have gained a few pounds.

assistant: Okay, your overall performance status in the E C O G scale is one.