Vascular ParkinsonismVascular parkinsonism is produced by one or more small strokes that affect the basal ganglia A stroke is the loss of activity of a discreet brain area lesion because of blockage of the blood supply to that brain region Vascular diseases are associated with a higher prevalence of Parkinsons Disease 1 There are three different pathologic states that produce Vascular Parkinsonism VP including multiple lacunar infarctions in the basal ganglia area 23 subcortical arteriosclerotic changes Binswangers disease 23 and a single vascular lesion that present a clinical picture indistinguishable from Parkinsons disease 234 Parkinsons Disease symptoms occur in Vascular Parkinsonism 512 However resting tremor is either reduced 56 or absent 78 Only a minority but a large minority of people with Vascular Parkinsonism respond to Ldopa 9101 Archives of Neurology 2006 63 5  717722 EDLouis JALuchsinger2 Journal of Neurology 2006 253 Supplement 3  iii16iii21 KFukimoto3 Journal of Neurology 2004 251 5  513524 ISibon GFenelon NPQuinn FTison4 Journal of Clinical Neuroscience 2001 8 3  268271 SPeters EGEising HPrzuntek TMuller5 Di Yi Jun Yi Da Xue Xue Bao 2005 25 7  868870 DQZhao6 Archives of Neurology 1999 56 1  98102 JWinikates JJankovic7 Acta Neurologica Scandinavica 1992 86 6  588592 CMChang YLYu HKNg SYLeung KYFong8 Stroke 1997 28 5  965969 HYamanouchi HNagura9 Journal of Neurology 2005 252 9  10451049 LRampello AAlvano GBattaglia RRaffaele IVecchio MMalaguarnera10 Journal of Neurological and Neurosurgical Psychiatry 2004 75 4  545547 JCZijlmans RKatzenschlager SEDaniel AJLees11 Acta Neurologica Scandinavica 2001 104 2  6367 MDemirkiran M Bozdemir H Sarica Y12 Movement Disorders 1996 11 5  501508 JCZijlmans PJPoels JDuysens Jvan der Straaten TThien MAvant Hof HOThijssen MWHorstink

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Vascular ParkinsonismVascular parkinsonism is produced by one or more small strokes that affect the basal ganglia A stroke is the loss of activity of a discreet brain area lesion because of blockage of the blood supply to that brain region Vascular diseases are associated with a higher prevalence of Parkinsons Disease 1 There are three different pathologic states that produce Vascular Parkinsonism VP including multiple lacunar infarctions in the basal ganglia area 23 subcortical arteriosclerotic changes Binswangers disease 23 and a single vascular lesion that present a clinical picture indistinguishable from Parkinsons disease 234 Parkinsons Disease symptoms occur in Vascular Parkinsonism 512 However resting tremor is either reduced 56 or absent 78 Only a minority but a large minority of people with Vascular Parkinsonism respond to Ldopa 9101 Archives of Neurology 2006 63 5  717722 EDLouis JALuchsinger2 Journal of Neurology 2006 253 Supplement 3  iii16iii21 KFukimoto3 Journal of Neurology 2004 251 5  513524 ISibon GFenelon NPQuinn FTison4 Journal of Clinical Neuroscience 2001 8 3  268271 SPeters EGEising HPrzuntek TMuller5 Di Yi Jun Yi Da Xue Xue Bao 2005 25 7  868870 DQZhao6 Archives of Neurology 1999 56 1  98102 JWinikates JJankovic7 Acta Neurologica Scandinavica 1992 86 6  588592 CMChang YLYu HKNg SYLeung KYFong8 Stroke 1997 28 5  965969 HYamanouchi HNagura9 Journal of Neurology 2005 252 9  10451049 LRampello AAlvano GBattaglia RRaffaele IVecchio MMalaguarnera10 Journal of Neurological and Neurosurgical Psychiatry 2004 75 4  545547 JCZijlmans RKatzenschlager SEDaniel AJLees11 Acta Neurologica Scandinavica 2001 104 2  6367 MDemirkiran M Bozdemir H Sarica Y12 Movement Disorders 1996 11 5  501508 JCZijlmans PJPoels JDuysens Jvan der Straaten TThien MAvant Hof HOThijssen MWHorstink

